# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DDT PF02791.17 ORY88367.1 - 6.6e-12 45.6 0.0 1.9e+02 2.5 0.0 15.5 15 0 0 15 15 15 0 DDT domain Sigma54_DBD PF04552.13 ORY88367.1 - 6.1e-08 32.5 89.9 1.7 8.3 0.2 19.4 13 4 8 23 23 23 11 Sigma-54, DNA binding domain Y2_Tnp PF04986.13 ORY88367.1 - 0.00059 19.9 1.6 53 3.8 0.0 6.6 6 1 0 6 6 6 0 Putative transposase IL4 PF00727.18 ORY88367.1 - 0.28 11.4 4.3 42 4.4 0.0 7.5 9 0 0 9 9 9 0 Interleukin 4 Serinc PF03348.15 ORY88526.1 - 7.2e-140 466.7 7.6 3.3e-135 451.4 7.6 2.0 1 1 0 1 1 1 1 Serine incorporator (Serinc) Oxysterol_BP PF01237.18 ORY88527.1 - 1.5e-115 386.0 1.7 1.5e-115 386.0 1.7 1.9 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 ORY88527.1 - 1.2e-20 73.6 0.1 3.9e-20 71.9 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY88527.1 - 4.7e-11 43.1 0.4 2.8e-08 34.2 0.1 3.0 3 0 0 3 3 3 2 PH domain GOLD_2 PF13897.6 ORY88527.1 - 8.6e-08 32.8 1.1 1.4e-05 25.6 0.1 3.4 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 ORY88527.1 - 0.028 14.4 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PH_11 PF15413.6 ORY88527.1 - 0.065 13.7 10.0 1 9.8 1.1 4.0 3 1 1 4 4 4 0 Pleckstrin homology domain EF-hand_1 PF00036.32 ORY88528.1 - 1.2e-24 84.0 9.8 8.6e-07 28.1 0.1 5.8 6 1 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 ORY88528.1 - 6.9e-24 84.1 4.6 2e-10 40.9 0.0 3.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY88528.1 - 2.6e-23 79.9 6.8 2.2e-06 27.1 0.0 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 ORY88528.1 - 6.3e-18 64.4 8.8 6.5e-09 35.5 0.0 4.9 3 3 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 ORY88528.1 - 7.5e-18 63.2 8.4 4e-05 22.9 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 ORY88528.1 - 8.9e-05 22.7 0.0 2.1 8.7 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain DUF5640 PF18692.1 ORY88528.1 - 0.0014 18.6 2.2 0.0056 16.7 0.4 2.5 1 1 2 3 3 3 1 Family of unknown function (DUF5640) Caleosin PF05042.13 ORY88528.1 - 0.15 12.0 4.4 1.3 8.9 1.3 3.2 1 1 2 3 3 3 0 Caleosin related protein EF-hand_14 PF17959.1 ORY88528.1 - 0.19 12.1 0.1 0.77 10.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Nup35_RRM PF05172.13 ORY88528.1 - 0.19 11.7 0.4 0.56 10.2 0.4 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EF-hand_4 PF12763.7 ORY88528.1 - 0.38 10.7 2.3 1.1 9.3 0.4 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Vasohibin PF14822.6 ORY88530.1 - 0.2 10.8 0.2 0.37 10.0 0.2 1.4 1 0 0 1 1 1 0 Vasohibin Herpes_gE PF02480.16 ORY88540.1 - 0.068 11.9 0.6 0.099 11.4 0.6 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Lectin_C PF00059.21 ORY88540.1 - 0.093 13.5 0.6 0.093 13.5 0.6 2.5 3 0 0 3 3 3 0 Lectin C-type domain S_4TM PF18159.1 ORY88540.1 - 0.35 10.1 2.4 0.56 9.5 2.4 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain RNA_pol_Rbc25 PF08292.12 ORY88541.1 - 2.3e-38 131.3 0.0 3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 ORY88541.1 - 1.3e-17 63.9 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORY88541.1 - 0.00018 21.8 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain C2 PF00168.30 ORY88542.1 - 2.4e-89 294.4 5.5 1.3e-20 73.6 0.1 6.2 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 ORY88542.1 - 0.0011 18.5 0.0 0.0023 17.4 0.0 1.6 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Calmodulin_bind PF07887.11 ORY88542.1 - 0.048 13.0 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Calmodulin binding protein-like DUF3408 PF11888.8 ORY88542.1 - 0.57 10.3 6.2 1.2 9.2 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Hemagglutinin PF00509.18 ORY88918.1 - 0.023 13.1 0.0 0.025 13.0 0.0 1.0 1 0 0 1 1 1 0 Haemagglutinin UPF0147 PF03685.13 ORY88920.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Exo_endo_phos_2 PF14529.6 ORY88924.1 - 1e-05 25.3 0.0 3.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 ORY88924.1 - 0.01 15.4 0.1 0.045 13.3 0.1 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 ORY88924.1 - 0.4 10.9 18.0 0.12 12.5 2.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 ORY88924.1 - 6.9 6.6 18.2 3.4 7.6 8.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Lactamase_B_4 PF13691.6 ORY88925.1 - 1.7e-16 59.6 0.1 5.3e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 ORY88925.1 - 4.2e-12 46.0 2.2 1.1e-11 44.7 1.1 2.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY88925.1 - 0.00059 19.9 0.1 0.002 18.2 0.1 1.9 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SNase PF00565.17 ORY88926.1 - 1.2e-05 25.7 0.5 0.00029 21.3 0.4 2.7 2 1 0 2 2 2 1 Staphylococcal nuclease homologue UPF0147 PF03685.13 ORY88932.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) 2H-phosphodiest PF08975.10 ORY88943.1 - 0.049 13.6 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) DUF4290 PF14123.6 ORY88943.1 - 0.099 12.2 0.5 0.14 11.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) Lyase_1 PF00206.20 ORY89181.1 - 7.2e-103 344.2 0.0 1e-102 343.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 ORY89181.1 - 3.6e-23 82.1 0.0 8.3e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FUSC PF04632.12 ORY89182.1 - 1.4 7.4 6.8 3.3 6.1 6.8 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family Not1 PF04054.15 ORY89183.1 - 2.4e-148 493.9 0.2 2.4e-148 493.9 0.2 2.0 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 ORY89183.1 - 4.2e-99 330.5 8.8 1.2e-98 329.0 8.8 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 ORY89183.1 - 6.5e-70 234.2 0.3 3.2e-69 231.9 0.3 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 ORY89183.1 - 3e-52 176.4 4.9 1.2e-51 174.5 4.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 ORY89183.1 - 3.8e-44 150.4 1.2 1.1e-43 148.8 1.2 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Herpes_pp85 PF04637.12 ORY89184.1 - 4.9 5.4 5.4 6.7 5.0 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) EphA2_TM PF14575.6 ORY89185.1 - 0.0081 17.0 0.0 0.02 15.7 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Gemini_mov PF01708.16 ORY89185.1 - 0.027 14.2 0.1 0.11 12.3 0.0 2.0 2 1 1 3 3 3 0 Geminivirus putative movement protein TMEM154 PF15102.6 ORY89185.1 - 0.034 14.1 0.3 0.063 13.2 0.3 1.6 1 1 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 ORY89185.1 - 0.041 14.0 0.9 0.072 13.2 0.9 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Podoplanin PF05808.11 ORY89185.1 - 0.052 13.7 0.3 0.083 13.0 0.3 1.2 1 0 0 1 1 1 0 Podoplanin DUF4381 PF14316.6 ORY89185.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) 7TM_GPCR_Srv PF10323.9 ORY89185.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Baculo_11_kDa PF06143.11 ORY89185.1 - 0.098 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1180 PF06679.12 ORY89185.1 - 0.17 12.3 1.5 0.32 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SCIMP PF15050.6 ORY89185.1 - 1 9.8 3.2 4.9 7.6 0.3 2.2 2 0 0 2 2 2 0 SCIMP protein RVT_1 PF00078.27 ORY89198.1 - 0.00077 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YabA PF06156.13 ORY89199.1 - 0.22 12.2 2.9 0.26 12.0 1.5 1.8 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 ORY89203.1 - 0.039 14.0 1.1 0.12 12.5 1.1 1.8 1 0 0 1 1 1 0 Basic region leucine zipper YabA PF06156.13 ORY89203.1 - 0.098 13.3 1.3 0.24 12.1 1.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 ORY89203.1 - 3.3 7.5 7.1 0.53 10.1 1.6 2.3 1 1 0 2 2 2 0 Septum formation initiator TRM PF02005.16 ORY89205.1 - 9e-134 446.4 0.0 1.1e-133 446.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 ORY89205.1 - 0.002 17.9 0.1 0.004 16.9 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 ORY89205.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY89205.1 - 0.023 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY89205.1 - 0.15 12.8 0.0 0.47 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 ORY89205.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PP-binding PF00550.25 ORY89206.1 - 1.2e-13 51.2 0.3 1.5e-13 50.8 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORY89206.1 - 5.6e-06 26.5 1.7 7e-06 26.2 1.7 1.2 1 0 0 1 1 1 1 Acyl-carrier Adaptin_N PF01602.20 ORY89207.1 - 5.9e-113 378.2 0.5 7.5e-113 377.9 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 ORY89207.1 - 2.1e-60 203.3 2.2 4.5e-60 202.2 2.2 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 ORY89207.1 - 5.8e-30 103.8 0.0 1.5e-29 102.5 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 ORY89207.1 - 2.3e-18 66.3 0.6 1.1e-09 38.5 0.0 4.7 3 1 1 4 4 4 4 HEAT repeats Cnd1 PF12717.7 ORY89207.1 - 4.3e-11 43.1 8.0 0.0021 18.1 0.0 4.4 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY89207.1 - 0.0015 18.6 6.2 2.2 8.7 0.1 6.1 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 ORY89207.1 - 0.0085 16.6 4.5 0.04 14.4 0.1 4.0 4 1 1 5 5 5 1 HEAT-like repeat HEAT_PBS PF03130.16 ORY89207.1 - 0.011 16.4 2.2 18 6.4 0.0 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat ThiF PF00899.21 ORY89208.1 - 6e-40 137.1 0.0 8.6e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORY89208.1 - 0.00014 22.2 0.3 0.0017 18.7 0.5 2.6 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 ORY89208.1 - 0.0023 17.3 0.2 0.0034 16.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ORY89208.1 - 0.017 15.5 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 ORY89208.1 - 0.027 14.1 0.8 0.064 12.8 0.4 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 ORY89208.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ORY89208.1 - 0.051 13.8 0.2 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 ORY89208.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY89208.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORY89208.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 ORY89208.1 - 0.13 12.9 0.3 4.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY89208.1 - 0.2 10.9 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PriA_CRR PF18319.1 ORY89209.1 - 0.88 9.6 11.1 2.3 8.3 4.0 2.6 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain MFS_1 PF07690.16 ORY89210.1 - 1e-41 143.0 22.4 1.2e-41 142.8 22.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89210.1 - 1.7e-11 43.6 9.8 1.7e-11 43.6 9.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY89210.1 - 8.1e-07 28.7 6.5 1.2e-06 28.1 6.5 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ORY89210.1 - 0.00067 18.2 4.8 0.00086 17.8 4.8 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 ORY89210.1 - 0.11 10.8 5.5 0.18 10.0 4.7 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ORY89211.1 - 2.7e-34 118.6 23.0 3.7e-34 118.2 23.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY89211.1 - 0.00036 19.9 7.9 0.00036 19.9 7.9 2.2 1 1 2 3 3 3 1 Uncharacterised MFS-type transporter YbfB ERGIC_N PF13850.6 ORY89211.1 - 0.2 12.1 2.9 15 6.0 0.1 3.1 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AAA PF00004.29 ORY89212.1 - 1.4e-62 210.0 0.0 6.4e-44 149.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY89212.1 - 1.7e-11 44.8 0.1 0.003 17.9 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 ORY89212.1 - 1.1e-08 34.8 4.1 4.4e-06 26.4 0.1 3.0 3 0 0 3 3 2 2 AAA+ lid domain AAA_18 PF13238.6 ORY89212.1 - 1.2e-08 35.6 0.0 0.012 16.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 ORY89212.1 - 1.9e-08 34.8 0.0 0.00044 20.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY89212.1 - 1e-07 32.0 0.0 0.013 15.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY89212.1 - 6.3e-07 29.7 0.7 0.024 14.9 0.1 3.3 3 1 0 3 3 2 2 AAA domain RuvB_N PF05496.12 ORY89212.1 - 6.6e-07 29.2 0.0 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY89212.1 - 8.6e-07 29.2 0.0 0.034 14.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 ORY89212.1 - 9.6e-07 28.3 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain TsaE PF02367.17 ORY89212.1 - 1.6e-06 28.1 0.0 0.047 13.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 ORY89212.1 - 1.7e-06 28.1 0.0 0.023 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORY89212.1 - 4.7e-06 26.9 0.0 0.033 14.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 ORY89212.1 - 2e-05 24.2 0.0 0.078 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Cytidylate_kin PF02224.18 ORY89212.1 - 4.6e-05 23.2 1.6 0.049 13.4 0.0 3.6 4 0 0 4 4 4 1 Cytidylate kinase Rad17 PF03215.15 ORY89212.1 - 4.9e-05 23.3 0.0 0.0026 17.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 ORY89212.1 - 8.1e-05 22.6 0.2 0.11 12.4 0.0 3.0 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 ORY89212.1 - 0.0001 22.1 0.0 0.0031 17.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 ORY89212.1 - 0.00012 22.2 0.0 0.011 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 ORY89212.1 - 0.00017 21.5 0.1 0.92 9.4 0.1 2.9 3 0 0 3 3 2 2 NACHT domain NB-ARC PF00931.22 ORY89212.1 - 0.00024 20.4 0.0 0.78 8.9 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain AAA_25 PF13481.6 ORY89212.1 - 0.00028 20.5 0.2 0.01 15.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 ORY89212.1 - 0.00028 20.1 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.6 ORY89212.1 - 0.00048 20.6 0.0 0.65 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ORY89212.1 - 0.00053 19.9 0.1 1.1 9.0 0.0 2.6 3 0 0 3 3 3 2 AAA domain NTPase_1 PF03266.15 ORY89212.1 - 0.00058 19.8 0.0 0.48 10.3 0.0 2.6 2 0 0 2 2 2 1 NTPase Mg_chelatase PF01078.21 ORY89212.1 - 0.00073 19.0 0.1 0.023 14.1 0.1 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ORY89212.1 - 0.001 18.8 0.4 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY89212.1 - 0.0011 19.5 0.0 2 8.9 0.0 2.9 3 0 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 ORY89212.1 - 0.0012 18.6 0.0 0.55 9.9 0.0 3.4 4 0 0 4 4 3 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 ORY89212.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 ORY89212.1 - 0.0012 18.6 0.1 0.1 12.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY89212.1 - 0.0023 17.7 0.1 3.3 7.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 ORY89212.1 - 0.0035 16.7 0.1 0.0092 15.3 0.0 1.7 2 0 0 2 2 1 1 KaiC Vps4_C PF09336.10 ORY89212.1 - 0.019 14.9 0.0 0.89 9.6 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 ORY89212.1 - 0.025 14.4 0.0 0.36 10.7 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ORY89212.1 - 0.045 13.5 0.0 11 5.7 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_6 PF12774.7 ORY89212.1 - 0.061 12.3 0.0 3.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 ORY89212.1 - 0.069 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.22 ORY89212.1 - 0.086 13.0 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 ORY89212.1 - 0.1 12.9 0.1 3.1 8.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY89212.1 - 0.17 11.8 0.2 4 7.3 0.0 2.7 3 0 0 3 3 2 0 RsgA GTPase AAA_23 PF13476.6 ORY89212.1 - 0.25 11.8 1.5 31 5.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Actin PF00022.19 ORY89214.1 - 2e-25 89.2 0.0 5.3e-25 87.9 0.0 1.6 1 1 0 1 1 1 1 Actin MFS_1 PF07690.16 ORY89215.1 - 1.8e-33 116.0 29.3 1.8e-33 116.0 29.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY89215.1 - 0.00016 21.1 4.1 0.00016 21.1 4.1 2.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF1772 PF08592.11 ORY89215.1 - 0.0003 21.1 3.6 0.042 14.2 0.0 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF1772) DUF4579 PF15158.6 ORY89215.1 - 0.03 14.1 4.4 0.6 9.8 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4579) DUF2243 PF10002.9 ORY89215.1 - 0.27 11.4 7.9 0.3 11.2 0.2 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2243) Glyoxalase PF00903.25 ORY89216.1 - 1.1e-19 70.9 1.2 2.3e-15 56.9 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY89216.1 - 3.4e-11 43.4 0.1 5.7e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 ORY89216.1 - 5.9e-09 36.2 0.2 1.6e-08 34.8 0.2 1.6 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 ORY89216.1 - 5.4e-06 26.6 0.9 0.00076 19.6 0.2 2.9 3 1 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ORY89216.1 - 0.051 14.4 1.7 0.89 10.4 0.3 2.8 2 2 0 2 2 2 0 Glyoxalase-like domain AhpC-TSA PF00578.21 ORY89217.1 - 4.4e-33 113.8 0.0 6.6e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 ORY89217.1 - 1.4e-12 47.2 0.1 3.1e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 ORY89217.1 - 1.7e-12 47.3 0.0 2.9e-12 46.5 0.0 1.4 2 0 0 2 2 2 1 Redoxin NUC153 PF08159.12 ORY89218.1 - 5.4e-05 22.9 3.9 0.0001 22.0 3.9 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 ORY89218.1 - 0.00028 21.1 0.0 0.16 12.2 0.0 3.2 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY89218.1 - 0.0009 20.0 0.1 11 7.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4416 PF14385.6 ORY89218.1 - 0.089 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Cullin_binding PF03556.15 ORY89219.1 - 1.6e-29 102.8 2.9 1.9e-29 102.5 2.9 1.2 1 0 0 1 1 1 1 Cullin binding OTU PF02338.19 ORY89221.1 - 0.0039 17.7 0.1 0.022 15.2 0.0 2.1 1 1 1 2 2 2 1 OTU-like cysteine protease ubiquitin PF00240.23 ORY89221.1 - 0.0089 15.8 0.0 0.046 13.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin family UN_NPL4 PF11543.8 ORY89221.1 - 0.088 13.3 0.0 0.27 11.8 0.0 1.8 2 1 0 2 2 2 0 Nuclear pore localisation protein NPL4 DEC-1_N PF04625.13 ORY89221.1 - 9.8 5.1 8.8 13 4.6 8.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RGS PF00615.19 ORY89223.1 - 1.7e-26 92.8 0.0 2.8e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 ORY89223.1 - 1.1e-12 47.7 0.1 4.6e-09 36.2 0.1 3.5 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_M35 PF02102.15 ORY89223.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family SPRY PF00622.28 ORY89224.1 - 3.1e-22 78.9 0.1 7.6e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 SPRY domain Cwf_Cwc_15 PF04889.12 ORY89224.1 - 4.8 6.9 8.8 0.98 9.1 5.2 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Arm PF00514.23 ORY89226.1 - 2.8e-08 33.5 0.0 0.036 14.1 0.0 4.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 ORY89226.1 - 7.8e-07 29.2 0.2 0.00047 20.2 0.0 2.4 2 0 0 2 2 2 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 ORY89226.1 - 0.00011 22.2 0.0 0.0066 16.4 0.0 2.6 1 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 ORY89226.1 - 0.0015 17.2 0.8 0.052 12.1 0.1 2.3 1 1 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 ORY89226.1 - 0.0019 18.3 1.7 0.15 12.4 0.1 3.7 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 ORY89226.1 - 0.0062 17.0 0.0 0.84 10.2 0.0 3.4 1 1 2 3 3 3 1 HEAT-like repeat TAtT PF16811.5 ORY89226.1 - 0.054 12.8 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 TRAP transporter T-component V-ATPase_H_N PF03224.14 ORY89226.1 - 0.054 12.8 0.1 0.16 11.2 0.1 1.8 1 1 0 1 1 1 0 V-ATPase subunit H Pneumo_M2 PF07380.11 ORY89227.1 - 0.099 12.9 0.4 0.14 12.5 0.4 1.3 1 0 0 1 1 1 0 Pneumovirus M2 protein PFK PF00365.20 ORY89228.1 - 3.5e-199 659.8 5.6 1.8e-110 368.8 1.5 2.0 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 ORY89228.1 - 0.053 13.1 0.2 0.3 10.7 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TP6A_N PF04406.14 ORY89229.1 - 1.6e-21 76.1 0.9 1.6e-21 76.1 0.9 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase HTH_psq PF05225.16 ORY89229.1 - 0.023 14.4 0.2 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain ING PF12998.7 ORY89230.1 - 4e-18 65.9 0.2 7.5e-18 65.0 0.2 1.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY89230.1 - 1.3e-06 28.1 7.6 2.3e-06 27.4 7.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORY89230.1 - 0.031 14.5 0.3 0.075 13.3 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain CK2S PF15011.6 ORY89230.1 - 0.05 13.5 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Casein Kinase 2 substrate Fib_alpha PF08702.10 ORY89230.1 - 0.079 13.2 2.6 8.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HrpB7 PF09486.10 ORY89230.1 - 0.097 13.1 3.4 0.5 10.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Peptidase_S49_N PF08496.10 ORY89232.1 - 0.079 13.0 3.8 0.079 13.0 3.8 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ndc1_Nup PF09531.10 ORY89236.1 - 0.19 10.4 2.6 0.23 10.1 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.10 ORY89237.1 - 0.19 10.4 2.6 0.23 10.1 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.10 ORY89244.1 - 0.19 10.4 2.6 0.23 10.1 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0147 PF03685.13 ORY89495.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) GYF PF02213.16 ORY89515.1 - 0.043 13.5 0.9 0.081 12.6 0.9 1.5 1 0 0 1 1 1 0 GYF domain DUF3323 PF11796.8 ORY89517.1 - 0.039 13.8 0.6 0.11 12.4 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Aft1_HRA PF11786.8 ORY89518.1 - 0.05 14.0 1.7 0.12 12.8 0.7 1.9 2 0 0 2 2 2 0 Aft1 HRA domain HTH_23 PF13384.6 ORY89519.1 - 0.0012 18.6 0.0 0.04 13.7 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 ORY89519.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 ORY89519.1 - 0.0046 17.6 0.0 0.0062 17.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.7 ORY89519.1 - 0.016 15.4 0.0 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1804 PF08822.11 ORY89519.1 - 0.024 14.6 0.3 0.072 13.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) HTH_29 PF13551.6 ORY89519.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Terminase_5 PF06056.12 ORY89519.1 - 0.11 12.4 0.1 0.89 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_32 PF13565.6 ORY89521.1 - 0.002 18.7 0.0 0.0044 17.6 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 ORY89521.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_IclR PF09339.10 ORY89521.1 - 0.021 14.6 0.0 0.12 12.2 0.0 2.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_AraC PF00165.23 ORY89521.1 - 0.024 14.7 0.0 0.091 12.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 ORY89521.1 - 0.072 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ORY89521.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix SpoIIID PF12116.8 ORY89521.1 - 0.13 12.3 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D DDE_3 PF13358.6 ORY89522.1 - 0.0034 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zinc_ribbon_6 PF14599.6 ORY89522.1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Zinc-ribbon GYF PF02213.16 ORY89523.1 - 0.043 13.5 0.9 0.081 12.6 0.9 1.5 1 0 0 1 1 1 0 GYF domain RPA_C PF08784.11 ORY89532.1 - 0.14 12.8 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Exo_endo_phos_2 PF14529.6 ORY89534.1 - 4.1e-18 65.3 1.4 7.8e-18 64.5 1.4 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 ORY89534.1 - 0.0029 17.2 1.2 0.0052 16.3 1.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MRJP PF03022.16 ORY89534.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Major royal jelly protein Ribosomal_L4 PF00573.22 ORY89536.1 - 3.8e-64 215.9 0.3 4.5e-64 215.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family AAA_19 PF13245.6 ORY89536.1 - 0.1 12.9 0.1 0.35 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF155 PF02582.14 ORY89537.1 - 4.6e-32 111.5 0.5 1.5e-20 74.0 0.0 3.2 2 2 1 3 3 3 2 Uncharacterised ACR, YagE family COG1723 Presenilin PF01080.17 ORY89537.1 - 0.0022 16.8 2.4 0.0022 16.8 2.4 2.5 3 0 0 3 3 3 1 Presenilin Spt20 PF12090.8 ORY89537.1 - 0.056 13.0 21.7 0.14 11.8 4.3 2.3 2 0 0 2 2 2 0 Spt20 family PNISR PF15996.5 ORY89537.1 - 0.52 10.6 19.6 0.82 9.9 14.4 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Zip PF02535.22 ORY89537.1 - 1.3 8.1 15.0 0.23 10.7 10.9 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter SLC12 PF03522.15 ORY89537.1 - 2.3 7.1 8.0 1.3 8.0 4.9 1.9 2 0 0 2 2 2 0 Solute carrier family 12 Polysacc_deac_1 PF01522.21 ORY89539.1 - 2.6e-22 79.0 0.0 4.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase V_cholerae_RfbT PF05575.11 ORY89539.1 - 0.15 11.3 0.1 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein Sugar_tr PF00083.24 ORY89540.1 - 1e-107 360.9 30.2 5e-77 259.7 15.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY89540.1 - 2e-22 79.6 19.7 2e-22 79.6 19.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 ORY89540.1 - 0.00038 20.9 5.8 0.00066 20.2 5.8 1.3 1 0 0 1 1 1 1 Plexin repeat Sad1_UNC PF07738.13 ORY89541.1 - 4.3e-31 107.7 0.1 7.3e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PepSY_TM PF03929.16 ORY89541.1 - 0.31 10.7 3.5 0.38 10.4 0.1 2.4 2 0 0 2 2 2 0 PepSY-associated TM region Sugar_tr PF00083.24 ORY89542.1 - 3.9e-118 395.2 15.8 4.6e-118 394.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY89542.1 - 4.2e-28 98.3 47.1 2.5e-23 82.6 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY89542.1 - 0.00022 19.9 6.5 0.00022 19.9 6.5 3.4 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 ORY89542.1 - 0.00084 17.9 6.6 0.0016 17.0 2.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF997 PF06196.12 ORY89542.1 - 0.52 10.3 0.1 0.52 10.3 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF997) UMP1 PF05348.11 ORY89544.1 - 6.7e-40 136.0 0.5 8.1e-40 135.7 0.5 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF667 PF05018.13 ORY89545.1 - 1.1e-77 259.9 0.1 1.3e-77 259.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) COQ7 PF03232.13 ORY89546.1 - 2.8e-77 258.3 0.1 3.3e-77 258.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 ORY89546.1 - 0.00077 19.9 0.2 0.049 14.0 0.0 1.7 1 1 1 2 2 2 2 Rubrerythrin AA_permease_N PF08403.10 ORY89546.1 - 0.095 12.2 0.0 0.32 10.5 0.0 1.9 1 1 1 2 2 2 0 Amino acid permease N-terminal DUF1241 PF06840.11 ORY89547.1 - 0.0053 16.4 0.0 0.0055 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DUF1640 PF07798.11 ORY89547.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Ncstrn_small PF18266.1 ORY89548.1 - 8.4e-42 143.0 0.0 1.9e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 ORY89548.1 - 3.4e-31 108.5 0.3 1.3e-30 106.6 0.3 1.8 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 ORY89548.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Dickkopf_N PF04706.12 ORY89548.1 - 0.061 13.8 2.0 0.19 12.2 2.0 1.9 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Glyco_transf_20 PF00982.21 ORY89549.1 - 8.7e-164 545.7 0.0 1.2e-163 545.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY89549.1 - 1.2e-76 256.9 0.0 2e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY89549.1 - 1.1e-05 25.4 0.0 0.036 13.8 0.1 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Epimerase PF01370.21 ORY89550.1 - 6e-52 176.5 0.0 2e-51 174.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY89550.1 - 1.5e-16 60.7 0.1 4.1e-16 59.3 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY89550.1 - 1.2e-06 27.9 0.3 9e-05 21.7 0.0 3.0 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY89550.1 - 0.00055 19.1 0.0 0.0016 17.6 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY89550.1 - 0.05 12.6 0.1 0.23 10.4 0.1 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family COX4 PF02936.14 ORY89552.1 - 8.9e-41 139.1 0.3 1.1e-40 138.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF624 PF04854.14 ORY89552.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF624 OTU PF02338.19 ORY89552.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 1 0 1 1 1 0 OTU-like cysteine protease Arrestin_N PF00339.29 ORY89553.1 - 9e-13 48.5 0.0 2e-12 47.4 0.0 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORY89553.1 - 4.8e-05 22.7 0.1 9.4e-05 21.8 0.0 1.4 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 ORY89553.1 - 6.8e-05 23.3 0.0 0.0012 19.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY89553.1 - 0.0051 16.5 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like SURF4 PF02077.15 ORY89554.1 - 3.7e-85 285.7 5.5 4.2e-85 285.6 5.5 1.0 1 0 0 1 1 1 1 SURF4 family Intg_mem_TP0381 PF09529.10 ORY89554.1 - 5.3 6.5 15.5 4.3 6.8 3.5 2.5 1 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) SGS PF05002.15 ORY89555.1 - 2e-34 117.5 1.0 2e-34 117.5 1.0 2.8 3 1 0 3 3 1 1 SGS domain CS PF04969.16 ORY89555.1 - 5e-15 56.3 0.4 1e-14 55.3 0.4 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 ORY89555.1 - 8.5e-06 25.4 4.8 0.0012 18.6 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY89555.1 - 0.0048 17.2 1.0 0.0048 17.2 1.0 3.9 1 1 3 4 4 4 2 Tetratricopeptide repeat PRIMA1 PF16101.5 ORY89555.1 - 0.011 15.8 2.1 0.02 14.9 2.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TPR_8 PF13181.6 ORY89555.1 - 0.014 15.6 0.1 0.014 15.6 0.1 4.1 5 1 0 5 5 3 0 Tetratricopeptide repeat Borrelia_P83 PF05262.11 ORY89555.1 - 0.015 13.9 14.5 0.022 13.3 14.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_2 PF07719.17 ORY89555.1 - 0.016 15.3 0.2 0.016 15.3 0.2 5.4 4 1 1 5 5 4 0 Tetratricopeptide repeat ISG65-75 PF11727.8 ORY89555.1 - 0.37 10.0 16.3 0.65 9.2 16.3 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein RR_TM4-6 PF06459.12 ORY89555.1 - 0.4 10.5 10.6 0.77 9.5 10.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3987 PF13148.6 ORY89555.1 - 1.1 8.2 17.8 2.8 6.9 17.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Presenilin PF01080.17 ORY89555.1 - 1.6 7.4 5.2 2.2 7.0 5.2 1.2 1 0 0 1 1 1 0 Presenilin Alanine_zipper PF11839.8 ORY89555.1 - 1.7 9.1 32.4 0.41 11.0 28.5 2.0 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Selenoprotein_S PF06936.11 ORY89555.1 - 2.1 8.1 13.1 5 6.9 13.1 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) RNA_pol_Rpc4 PF05132.14 ORY89555.1 - 5.6 7.4 10.9 11 6.4 10.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN7 PF10602.9 ORY89555.1 - 6.9 6.3 12.1 0.47 10.1 0.1 2.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 AAA_12 PF13087.6 ORY89556.1 - 3.1e-41 141.2 0.0 5e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY89556.1 - 8.1e-24 84.8 0.0 1.7e-16 60.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF2439 PF10382.9 ORY89556.1 - 1.3e-17 63.8 0.4 3e-17 62.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.18 ORY89556.1 - 1.3e-05 25.0 0.0 0.69 9.6 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ORY89556.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 ORY89556.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ORY89556.1 - 0.12 12.0 0.0 0.88 9.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 ORY89557.1 - 0.0028 18.5 0.2 0.019 15.8 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89557.1 - 0.0049 17.1 0.0 0.033 14.5 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY89558.1 - 1e-13 51.5 0.0 0.2 12.6 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Lactonase PF10282.9 ORY89558.1 - 0.00087 18.6 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 ORY89558.1 - 0.0011 19.2 0.0 0.1 12.9 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY89558.1 - 0.0095 15.5 0.0 0.027 14.1 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 ORY89558.1 - 0.023 15.2 0.1 1.6 9.3 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain Pribosyl_synth PF14572.6 ORY89559.1 - 9.2e-40 136.6 0.7 2.5e-34 118.9 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORY89559.1 - 1.3e-36 125.0 0.0 7.3e-36 122.6 0.0 2.2 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORY89559.1 - 7.4e-12 45.1 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORY89559.1 - 0.029 13.8 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pep_deformylase PF01327.21 ORY89559.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Polypeptide deformylase Acyl-CoA_dh_1 PF00441.24 ORY89561.1 - 6.1e-45 153.1 1.8 6.1e-45 153.1 1.8 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY89561.1 - 2.1e-24 86.4 0.0 7.9e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY89561.1 - 9.6e-24 83.4 0.0 1.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY89561.1 - 3e-19 69.6 0.1 5e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY89561.1 - 0.012 15.3 0.1 0.039 13.6 0.1 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Heme_oxygenase PF01126.20 ORY89562.1 - 1.2e-53 182.0 0.5 1.6e-53 181.6 0.5 1.2 1 0 0 1 1 1 1 Heme oxygenase Orexin_rec2 PF03827.13 ORY89562.1 - 0.2 11.7 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Orexin receptor type 2 PBP_N PF17093.5 ORY89563.1 - 0.045 14.0 0.2 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus DUF4271 PF14093.6 ORY89563.1 - 0.068 13.1 2.9 0.32 10.9 2.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF4407 PF14362.6 ORY89563.1 - 0.11 11.8 0.2 1.7 7.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 ORY89564.1 - 0.0015 18.6 15.5 0.0015 18.6 15.5 14.6 3 2 8 14 14 14 2 Afadin- and alpha -actinin-Binding Filament PF00038.21 ORY89564.1 - 0.006 16.2 26.2 0.006 16.2 26.2 9.5 2 1 5 8 8 8 4 Intermediate filament protein Fungal_trans PF04082.18 ORY89565.1 - 5.7e-32 110.8 0.3 1.3e-31 109.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY89565.1 - 3.9e-10 39.7 11.4 7e-10 38.9 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC53 PF10152.9 ORY89565.1 - 0.14 12.6 1.7 0.33 11.4 0.4 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Dicty_REP PF05086.12 ORY89565.1 - 0.62 8.0 2.3 0.88 7.5 2.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Imm5 PF14423.6 ORY89565.1 - 0.66 10.2 3.9 1.4 9.1 3.9 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 Ribosomal_60s PF00428.19 ORY89565.1 - 6.3 7.5 7.1 0.22 12.2 0.5 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein HAP1_N PF04849.13 ORY89851.1 - 0.0039 16.4 6.7 0.0058 15.9 6.7 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ZapB PF06005.12 ORY89851.1 - 0.02 15.3 3.1 0.02 15.3 3.1 2.5 2 1 0 2 2 1 0 Cell division protein ZapB bZIP_Maf PF03131.17 ORY89851.1 - 0.03 14.8 1.6 0.03 14.8 1.6 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor YabA PF06156.13 ORY89851.1 - 0.079 13.6 0.3 0.079 13.6 0.3 2.1 2 0 0 2 2 2 0 Initiation control protein YabA TFIIA PF03153.13 ORY89851.1 - 0.092 12.7 17.7 0.11 12.4 17.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rootletin PF15035.6 ORY89851.1 - 0.51 10.3 12.4 1.1 9.3 12.4 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3464 PF11947.8 ORY89851.1 - 0.62 9.8 4.0 1.5 8.6 4.0 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4484 PF14831.6 ORY89851.1 - 1.2 9.2 4.2 1.7 8.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Elf1 PF05129.13 ORY89851.1 - 1.3 9.2 4.0 0.36 10.9 0.3 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF3408 PF11888.8 ORY89851.1 - 2.5 8.2 6.8 5.6 7.1 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF5327 PF17261.2 ORY89851.1 - 2.7 8.8 15.9 1.8 9.3 11.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF3391 PF11871.8 ORY89851.1 - 3.9 8.0 14.8 7.5 7.1 13.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Spt20 PF12090.8 ORY89851.1 - 4.9 6.7 23.7 12 5.4 19.8 2.1 2 0 0 2 2 2 0 Spt20 family HTH_ABP1_N PF18107.1 ORY89852.1 - 3.4e-09 36.3 0.4 4.1e-09 36.0 0.4 1.2 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain CENP-B_N PF04218.13 ORY89852.1 - 0.002 17.7 0.2 0.012 15.2 0.2 2.1 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 ORY89852.1 - 0.0061 17.1 0.1 0.0075 16.9 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sterol_MT_C PF08498.10 ORY89862.1 - 1.8e-28 98.6 1.0 3.6e-28 97.7 1.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ORY89862.1 - 3.3e-19 69.3 0.1 3.3e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY89862.1 - 5.5e-17 62.3 0.0 8.8e-16 58.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY89862.1 - 2.7e-16 59.7 0.0 4.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY89862.1 - 6.4e-11 42.0 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY89862.1 - 4.2e-10 39.7 0.0 1e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ORY89862.1 - 5.3e-10 39.0 0.0 8.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 ORY89862.1 - 3.4e-09 37.4 0.1 4.4e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 ORY89862.1 - 0.0037 17.1 0.0 0.15 11.8 0.1 2.2 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORY89862.1 - 0.0065 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 ORY89862.1 - 0.0077 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 ORY89862.1 - 0.028 14.4 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 ORY89862.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spb1_C PF07780.12 ORY89863.1 - 1.9e-74 249.9 35.8 1.9e-74 249.9 35.8 4.5 3 2 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 ORY89863.1 - 2.7e-57 193.8 0.4 6.5e-57 192.5 0.1 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 ORY89863.1 - 2.3e-47 160.8 14.3 2.3e-47 160.8 14.3 6.2 2 1 3 5 5 5 1 Domain of unknown function (DUF3381) RINT1_TIP1 PF04437.13 ORY89864.1 - 2.2e-89 300.6 0.3 3.5e-89 300.0 0.3 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family LZ_Tnp_IS66 PF13007.7 ORY89864.1 - 0.054 14.3 0.1 0.13 13.1 0.1 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain EzrA PF06160.12 ORY89864.1 - 0.1 10.8 0.4 2.6 6.1 0.1 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 ORY89864.1 - 3 7.9 8.1 14 5.7 0.8 4.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 ORY89866.1 - 2.5e-72 243.4 0.6 5.4e-72 242.3 0.6 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89866.1 - 1.1e-51 175.6 0.5 2.3e-51 174.5 0.5 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY89866.1 - 6.3e-18 64.9 0.0 6.3e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 ORY89866.1 - 5.8e-11 42.8 0.5 1.4e-10 41.6 0.5 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORY89866.1 - 5.6e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY89866.1 - 0.0015 17.4 20.5 0.023 13.5 20.5 2.3 1 1 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 ORY89866.1 - 0.01 16.2 6.8 0.033 14.6 0.6 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain TFIIA PF03153.13 ORY89866.1 - 0.16 11.9 31.0 0.28 11.1 31.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PH_9 PF15410.6 ORY89866.1 - 7.3 7.0 12.3 1.9 8.9 0.2 3.7 3 1 0 3 3 3 0 Pleckstrin homology domain STE PF02200.16 ORY89867.1 - 3.2e-53 178.8 0.0 4.9e-53 178.2 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 ORY89867.1 - 0.01 16.2 1.5 0.01 16.2 1.5 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY89867.1 - 0.013 16.3 10.4 0.38 11.7 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger LIP1 PF15904.5 ORY89867.1 - 0.055 13.8 0.7 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 Amino_oxidase PF01593.24 ORY89868.1 - 6.3e-62 210.3 0.2 4.5e-61 207.5 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY89868.1 - 6.2e-10 39.2 0.7 1.4e-09 38.0 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY89868.1 - 3.5e-05 23.2 0.1 0.00018 20.9 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY89868.1 - 0.00025 20.4 0.1 0.00046 19.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.21 ORY89868.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Pyr_redox_3 PF13738.6 ORY89868.1 - 0.0011 18.2 0.2 0.015 14.5 0.2 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY89868.1 - 0.0011 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY89868.1 - 0.0012 18.5 4.7 0.0042 16.7 3.5 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY89868.1 - 0.0044 16.2 0.5 0.0073 15.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORY89868.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY89868.1 - 0.021 14.1 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORY89868.1 - 0.038 13.1 0.5 0.058 12.5 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 ORY89868.1 - 0.046 12.4 0.3 0.09 11.5 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ORY89868.1 - 0.11 13.1 1.1 3.2 8.4 0.2 3.3 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY89868.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ORY89868.1 - 0.14 12.4 0.1 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain RRN3 PF05327.11 ORY89869.1 - 7.1e-155 516.7 10.5 7.1e-155 516.7 10.5 2.0 1 1 1 2 2 1 1 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 ORY89869.1 - 0.0078 16.6 23.4 0.51 10.8 12.7 2.7 2 0 0 2 2 2 2 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 ORY89869.1 - 0.04 13.6 19.8 0.64 9.7 7.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 ORY89869.1 - 0.11 12.6 19.5 0.15 12.2 2.8 2.1 2 0 0 2 2 2 0 YL1 nuclear protein FAD_binding_7 PF03441.14 ORY89869.1 - 0.17 11.3 3.3 0.29 10.6 0.2 2.7 3 1 1 4 4 4 0 FAD binding domain of DNA photolyase PCI PF01399.27 ORY89869.1 - 0.46 11.0 2.9 1.2 9.7 1.6 2.3 2 1 0 2 2 2 0 PCI domain NOA36 PF06524.12 ORY89869.1 - 0.53 9.6 18.1 0.17 11.2 6.5 2.4 2 0 0 2 2 2 0 NOA36 protein RXT2_N PF08595.11 ORY89869.1 - 1.4 9.0 10.7 1.9 8.5 3.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.14 ORY89869.1 - 1.4 7.1 11.3 3.1 6.0 4.4 2.1 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.6 ORY89869.1 - 1.6 9.2 18.4 0.75 10.2 1.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF913 PF06025.12 ORY89869.1 - 2.1 7.2 4.7 6.2 5.7 0.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) AIM3 PF17096.5 ORY89869.1 - 2.2 9.3 5.6 0.75 10.8 0.4 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Tub_N PF16322.5 ORY89869.1 - 2.8 8.3 10.2 7.2 7.0 2.9 2.4 2 0 0 2 2 2 0 Tubby N-terminal DUF4724 PF15852.5 ORY89869.1 - 5.7 7.5 5.7 0.49 10.9 0.2 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4724) Sigma70_ner PF04546.13 ORY89869.1 - 8.1 6.3 16.7 1.7 8.4 5.0 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region TFIIA PF03153.13 ORY89870.1 - 0.006 16.6 18.7 0.0073 16.4 18.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PEN-2 PF10251.9 ORY89870.1 - 0.012 16.0 0.1 0.029 14.8 0.1 1.6 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Presenilin PF01080.17 ORY89870.1 - 0.065 12.0 7.6 0.084 11.6 7.6 1.3 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 ORY89870.1 - 0.089 12.4 22.1 0.16 11.6 22.1 1.4 1 0 0 1 1 1 0 Spt20 family VIT1 PF01988.19 ORY89870.1 - 0.13 12.1 2.1 0.25 11.2 2.1 1.4 1 0 0 1 1 1 0 VIT family Cellulose_synt PF03552.14 ORY89870.1 - 0.26 9.7 3.4 0.35 9.3 3.4 1.1 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.12 ORY89870.1 - 0.29 10.1 11.1 0.33 9.9 11.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spo7 PF03907.13 ORY89870.1 - 0.35 10.3 8.9 0.35 10.3 0.7 2.6 2 1 1 3 3 3 0 Spo7-like protein MAS20 PF02064.15 ORY89870.1 - 0.77 9.9 14.0 0.066 13.3 9.3 1.7 2 0 0 2 2 2 0 MAS20 protein import receptor DUF3464 PF11947.8 ORY89870.1 - 0.82 9.4 12.0 1.8 8.3 12.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MDM10 PF12519.8 ORY89870.1 - 0.93 8.3 5.2 1.1 8.1 5.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Orf78 PF06024.12 ORY89870.1 - 1.4 9.2 6.5 17 5.8 4.8 2.4 2 0 0 2 2 2 0 Orf78 (ac78) CLN3 PF02487.17 ORY89870.1 - 1.9 7.4 6.8 3 6.8 6.8 1.2 1 0 0 1 1 1 0 CLN3 protein PAT1 PF09770.9 ORY89870.1 - 2.1 6.5 19.9 2.6 6.2 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GNAT_acetyltr_2 PF13718.6 ORY89870.1 - 2.4 7.5 7.5 4.1 6.7 7.5 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 EIIBC-GUT_N PF03612.14 ORY89870.1 - 4.5 7.0 10.0 7.5 6.2 10.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.19 ORY89870.1 - 5.1 4.9 9.9 1.3 6.8 6.7 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Sarcoglycan_1 PF04790.13 ORY89870.1 - 6 6.1 6.8 1 8.6 1.1 2.0 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein Connexin PF00029.19 ORY89870.1 - 6.4 6.5 11.6 0.87 9.3 5.7 2.2 2 1 0 2 2 2 0 Connexin DUF4770 PF15994.5 ORY89870.1 - 8.1 6.6 21.8 4.5 7.5 19.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4770) Coilin_N PF15862.5 ORY89870.1 - 8.8 6.1 17.4 21 4.9 17.4 1.6 1 0 0 1 1 1 0 Coilin N-terminus FHIPEP PF00771.20 ORY89870.1 - 9.2 4.6 7.0 12 4.2 7.0 1.2 1 0 0 1 1 1 0 FHIPEP family MFS_1 PF07690.16 ORY89873.1 - 2.4e-30 105.7 51.0 1.3e-29 103.3 37.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY89873.1 - 7.8e-11 41.2 30.6 7.1e-09 34.7 10.2 2.9 1 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 ORY89873.1 - 1.7 7.4 35.1 0.015 14.2 4.7 3.0 2 1 1 3 3 3 0 Sugar (and other) transporter Herpes_US9 PF06072.11 ORY89873.1 - 2.7 7.9 5.5 37 4.3 0.6 3.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 E1-E2_ATPase PF00122.20 ORY89873.1 - 3.7 7.0 6.7 0.24 10.9 0.4 2.2 3 0 0 3 3 3 0 E1-E2 ATPase DnaJ PF00226.31 ORY89875.1 - 1.2e-09 38.1 0.6 2.9e-09 36.9 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Iso_dh PF00180.20 ORY89876.1 - 3e-100 335.8 0.1 3.8e-100 335.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Copine PF07002.16 ORY89876.1 - 0.15 11.5 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Copine DUF1845 PF08900.11 ORY89878.1 - 0.091 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Sacchrp_dh_C PF16653.5 ORY89879.1 - 1.5e-92 310.5 0.0 3.3e-92 309.3 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY89879.1 - 4.2e-24 85.3 0.3 7.1e-24 84.5 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY89879.1 - 8.2e-06 25.9 0.1 1.9e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 ORY89879.1 - 0.0028 18.3 0.1 0.0052 17.4 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORY89879.1 - 0.0037 17.2 0.2 0.0065 16.4 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY89879.1 - 0.057 12.9 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY89879.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ORY89879.1 - 0.1 12.1 0.6 1.2 8.7 1.3 2.1 2 1 1 3 3 3 0 Enoyl-(Acyl carrier protein) reductase Recep_L_domain PF01030.24 ORY89880.1 - 5.3e-10 39.4 0.9 0.0025 17.9 0.0 4.6 2 1 2 4 4 4 2 Receptor L domain Ecm33 PF12454.8 ORY89880.1 - 0.01 16.0 7.5 0.053 13.7 1.7 3.2 1 1 1 2 2 2 0 GPI-anchored cell wall organization protein Bromo_TP PF07524.13 ORY89880.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated LRR_4 PF12799.7 ORY89880.1 - 1.2 9.6 4.7 51 4.5 0.0 4.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 ORY89881.1 - 7.9e-34 117.1 19.1 9.7e-34 116.8 19.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89881.1 - 6.1e-13 48.4 0.9 6.1e-13 48.4 0.9 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY89881.1 - 0.0085 14.6 0.1 0.013 13.9 0.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 ORY89882.1 - 7e-89 298.7 0.0 9.8e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NUDIX PF00293.28 ORY89885.1 - 9.7e-13 48.3 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CRAL_TRIO PF00650.20 ORY89886.1 - 2.3e-37 128.2 0.0 3.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY89886.1 - 7.2e-12 45.3 0.0 1.9e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY89886.1 - 5.5e-07 29.8 0.0 8.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBA_4 PF14555.6 ORY89886.1 - 0.14 12.0 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain Glyco_hydro_18 PF00704.28 ORY89887.1 - 3.3e-63 214.3 7.1 4.1e-63 214.0 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RRP36 PF06102.12 ORY89888.1 - 8.1e-49 165.8 29.9 8.1e-49 165.8 29.9 2.0 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 TAFII28 PF04719.14 ORY89889.1 - 4.3e-36 122.9 0.1 5.1e-36 122.6 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region GRIM-19 PF06212.12 ORY89889.1 - 0.12 12.4 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 GRIM-19 protein DUF4119 PF13494.6 ORY89890.1 - 0.0094 16.1 3.2 0.017 15.3 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF4119) Sporozoite_P67 PF05642.11 ORY89890.1 - 0.014 13.6 12.3 0.018 13.1 12.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.13 ORY89890.1 - 0.49 10.3 34.1 0.56 10.1 34.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rot1 PF10681.9 ORY89890.1 - 0.62 9.5 6.1 0.18 11.3 0.3 2.1 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal PPP4R2 PF09184.11 ORY89890.1 - 1.1 8.8 19.4 1.4 8.5 19.4 1.2 1 0 0 1 1 1 0 PPP4R2 Thg1C PF14413.6 ORY89890.1 - 1.1 9.5 10.6 0.57 10.3 7.0 2.1 2 0 0 2 2 2 0 Thg1 C terminal domain HMG14_17 PF01101.18 ORY89890.1 - 1.9 9.5 15.1 0.43 11.6 11.5 1.8 2 0 0 2 2 2 0 HMG14 and HMG17 CDC45 PF02724.14 ORY89890.1 - 2 6.6 13.5 2.6 6.2 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORY89890.1 - 3.1 7.5 16.0 3.8 7.3 16.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 ORY89890.1 - 6.5 5.4 17.1 7.5 5.2 17.1 1.1 1 0 0 1 1 1 0 Raftlin DUF4551 PF15087.6 ORY89890.1 - 8 5.2 20.7 10 4.8 20.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Suf PF05843.14 ORY89890.1 - 8.1 6.3 19.5 9.8 6.1 19.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ank_2 PF12796.7 ORY89891.1 - 1.3e-27 96.1 2.0 2.8e-11 43.9 1.3 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY89891.1 - 3.2e-20 70.1 6.3 0.29 11.8 0.0 9.1 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 ORY89891.1 - 1.4e-15 57.4 4.4 0.00038 21.0 0.4 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 ORY89891.1 - 2e-12 47.0 11.6 0.58 10.7 0.0 7.8 5 1 2 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 ORY89891.1 - 3.7e-10 39.8 11.7 0.33 11.3 0.1 6.9 2 1 6 8 8 8 4 Ankyrin repeats (many copies) Pilus_CpaD PF09476.10 ORY89891.1 - 0.062 13.0 1.1 0.46 10.2 0.2 2.4 2 1 0 3 3 3 0 Pilus biogenesis CpaD protein (pilus_cpaD) ABC_membrane PF00664.23 ORY89892.1 - 1.6e-48 165.8 7.8 2.4e-48 165.2 7.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY89892.1 - 1.1e-29 103.6 0.0 2.2e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.15 ORY89892.1 - 0.00016 21.2 0.6 0.00027 20.5 0.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 APS_kinase PF01583.20 ORY89892.1 - 0.0007 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 ORY89892.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY89892.1 - 0.0018 18.6 0.0 0.0048 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 ORY89892.1 - 0.0043 17.6 0.0 0.0076 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY89892.1 - 0.0046 16.7 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ORY89892.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ORY89892.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY89892.1 - 0.026 14.7 0.0 0.064 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY89892.1 - 0.034 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 ORY89892.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY89892.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 ORY89892.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_23 PF13476.6 ORY89892.1 - 0.081 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY89892.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ORY89892.1 - 0.087 12.5 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3808 PF10300.9 ORY89893.1 - 6.5e-42 143.9 5.2 2.1e-41 142.2 1.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_2 PF07719.17 ORY89893.1 - 0.00011 22.1 0.9 0.3 11.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY89893.1 - 0.0014 18.9 0.1 0.37 11.1 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat PEP-utilisers_N PF05524.13 ORY89894.1 - 0.08 13.1 1.0 0.14 12.3 1.0 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal PP2C PF00481.21 ORY89895.1 - 3.8e-46 157.8 0.0 6.6e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 ORY89895.1 - 4.5e-40 135.2 62.7 4.9e-08 32.6 1.0 10.8 5 3 5 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 ORY89895.1 - 1.2e-33 114.5 69.3 0.0001 22.6 0.7 12.8 8 2 7 15 15 15 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 ORY89895.1 - 8.3e-28 97.3 0.0 2.3e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 ORY89895.1 - 4.5e-07 29.5 17.5 0.02 14.4 0.4 5.4 3 2 2 5 5 5 3 Leucine-rich repeat RA PF00788.23 ORY89895.1 - 0.00064 20.3 0.0 0.0019 18.8 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_1 PF00560.33 ORY89895.1 - 0.0085 16.5 57.4 1.4 9.8 0.5 14.9 18 3 0 18 18 18 3 Leucine Rich Repeat Rsc14 PF08586.10 ORY89895.1 - 0.15 12.9 1.9 0.48 11.3 1.9 1.8 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit TFIIA PF03153.13 ORY89895.1 - 1.2 9.1 24.9 0.35 10.8 12.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PH PF00169.29 ORY89896.1 - 4.6e-10 39.9 0.1 8e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 PH domain Roughex PF06020.11 ORY89896.1 - 0.12 11.5 1.8 0.13 11.3 1.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF4611 PF15387.6 ORY89896.1 - 0.16 12.2 3.6 0.41 10.9 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.11 ORY89896.1 - 0.29 9.2 11.8 0.36 8.8 11.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 ORY89896.1 - 0.32 10.7 3.1 0.55 9.9 3.1 1.3 1 0 0 1 1 1 0 FAM176 family Ndc1_Nup PF09531.10 ORY89896.1 - 4.8 5.8 10.5 5.8 5.5 10.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 ORY89896.1 - 8.2 5.1 5.6 10 4.7 5.6 1.2 1 0 0 1 1 1 0 Presenilin CS PF04969.16 ORY89897.1 - 2.2e-08 35.0 0.0 5.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 CS domain Transketolase_N PF00456.21 ORY89898.1 - 1.3e-151 504.3 0.0 1.6e-151 504.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY89898.1 - 3e-44 150.8 0.0 6.8e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY89898.1 - 2.8e-14 53.0 0.0 1.1e-13 51.2 0.0 2.0 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY89898.1 - 0.00034 19.9 0.0 0.0007 18.9 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ORY89898.1 - 0.0057 16.5 0.8 0.17 11.7 0.8 2.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Alba PF01918.21 ORY89898.1 - 0.028 14.2 1.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Alba E1_dh PF00676.20 ORY89898.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Glyco_transf_28 PF03033.20 ORY89898.1 - 0.1 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain tRNA-synt_1d PF00750.19 ORY89899.1 - 4.9e-75 252.7 0.1 1.1e-74 251.5 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY89899.1 - 1.2e-25 89.9 0.2 4.1e-25 88.3 0.1 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ORY89899.1 - 7.3e-08 32.9 0.0 1.7e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain RNA_pol_N PF01194.17 ORY89901.1 - 3.1e-33 113.9 0.3 3.6e-33 113.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit TPR_MLP1_2 PF07926.12 ORY89902.1 - 0.027 14.5 13.7 0.081 13.0 13.7 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SLATT_6 PF18169.1 ORY89902.1 - 0.17 11.5 0.8 0.29 10.7 0.8 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Ribosomal_L18A PF01775.17 ORY89903.1 - 2.1e-54 182.8 0.7 2.7e-54 182.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Put_DNA-bind_N PF06971.13 ORY89903.1 - 0.015 15.3 0.3 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus Aminotran_1_2 PF00155.21 ORY89904.1 - 3.7e-23 82.3 0.0 4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORY89904.1 - 3.1e-08 32.8 0.0 4.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Collagen PF01391.18 ORY89904.1 - 0.19 11.5 4.9 0.31 10.8 4.9 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ctr PF04145.15 ORY89905.1 - 6.3e-26 91.8 0.0 7.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Treacle PF03546.14 ORY89905.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle DAP PF15228.6 ORY89905.1 - 0.14 13.4 0.0 0.2 12.8 0.0 1.2 1 0 0 1 1 1 0 Death-associated protein Ctr PF04145.15 ORY89906.1 - 2.9e-26 92.9 0.5 3.5e-26 92.6 0.5 1.0 1 0 0 1 1 1 1 Ctr copper transporter family FA_desaturase PF00487.24 ORY89906.1 - 2 8.2 5.4 5.4 6.8 0.5 2.1 1 1 1 2 2 2 0 Fatty acid desaturase Ion_trans PF00520.31 ORY89907.1 - 1.4e-109 365.1 60.5 2.5e-40 138.2 9.5 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 ORY89907.1 - 0.00049 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Aminotran_1_2 PF00155.21 ORY89909.1 - 1.1e-40 139.9 0.0 1.6e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY89909.1 - 0.043 13.1 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.7 ORY89909.1 - 0.072 11.9 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF4448 PF14610.6 ORY89911.1 - 0.14 11.9 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LIM PF00412.22 ORY89913.1 - 6.5e-53 176.8 36.0 5.5e-15 55.3 3.6 4.2 4 0 0 4 4 4 4 LIM domain Mononeg_mRNAcap PF14318.6 ORY89913.1 - 0.039 13.2 0.5 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 Mononegavirales mRNA-capping region V DZR PF12773.7 ORY89913.1 - 0.21 11.6 29.3 1.6 8.8 0.9 5.3 2 2 2 4 4 4 0 Double zinc ribbon DiS_P_DiS PF06750.13 ORY89913.1 - 1.9 8.7 8.2 14 5.9 0.1 4.5 3 1 1 4 4 4 0 Bacterial Peptidase A24 N-terminal domain C1_4 PF07975.12 ORY89913.1 - 2.6 8.4 20.9 2.7 8.3 0.8 4.4 4 1 0 4 4 4 0 TFIIH C1-like domain Ribosomal_L37e PF01907.19 ORY89913.1 - 4.3 7.6 19.3 0.76 10.0 0.1 4.8 5 0 0 5 5 5 0 Ribosomal protein L37e zf_UBZ PF18439.1 ORY89913.1 - 4.3 7.0 21.6 5 6.8 0.5 6.5 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 ORY89913.1 - 9 6.3 18.9 0.24 11.3 0.6 4.4 4 0 0 4 4 4 0 Putative transposase DNA-binding domain Aldo_ket_red PF00248.21 ORY89922.1 - 1.6e-44 152.3 0.0 2.2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pribosyltran_N PF13793.6 ORY89923.1 - 1.8e-49 166.5 1.0 1.4e-47 160.4 0.1 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORY89923.1 - 1.1e-45 155.9 5.0 9.4e-38 130.1 1.6 2.8 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORY89923.1 - 2.1e-14 53.4 3.7 2.9e-14 52.9 0.8 2.2 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPF0181 PF03701.14 ORY89923.1 - 0.035 13.8 0.2 0.37 10.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) UPRTase PF14681.6 ORY89923.1 - 0.062 12.7 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MFS_1 PF07690.16 ORY89924.1 - 9.8e-46 156.3 31.2 3.5e-42 144.6 18.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89924.1 - 1.8e-11 43.6 29.9 2.4e-10 39.9 29.9 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORY89924.1 - 0.00018 20.1 5.3 0.00033 19.2 5.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY89924.1 - 0.001 17.6 4.4 0.001 17.6 4.4 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1 PF07690.16 ORY89925.1 - 1.9e-50 171.8 25.4 3.1e-50 171.1 25.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89925.1 - 2.4e-09 36.6 10.0 2.4e-09 36.6 10.0 3.5 3 0 0 3 3 3 2 Sugar (and other) transporter DUF5058 PF16481.5 ORY89925.1 - 0.019 14.7 2.4 0.03 14.0 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5058) MFS_3 PF05977.13 ORY89925.1 - 0.028 12.8 1.0 0.056 11.8 1.0 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector DUF2052 PF09747.9 ORY89925.1 - 0.34 11.0 5.7 0.45 10.6 5.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Med18 PF09637.10 ORY89926.1 - 1.4e-06 28.3 0.0 0.00011 22.2 0.0 2.0 1 1 0 1 1 1 1 Med18 protein Fer2_3 PF13085.6 ORY89926.1 - 0.17 11.9 0.0 0.58 10.2 0.0 1.8 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain LRR_8 PF13855.6 ORY89927.1 - 1.9e-28 98.0 13.8 3.7e-10 39.4 0.1 2.8 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY89927.1 - 2e-14 53.5 2.8 3.9e-07 30.3 0.2 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY89927.1 - 1.2e-07 31.3 5.8 0.33 11.7 0.3 5.1 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY89927.1 - 0.0058 16.6 3.4 12 6.2 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 ORY89927.1 - 0.088 12.3 0.8 0.31 10.5 0.7 1.8 1 1 0 1 1 1 0 Leucine-rich repeat F-box-like PF12937.7 ORY89928.1 - 2.1e-05 24.3 0.5 2.1e-05 24.3 0.5 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY89928.1 - 0.00096 19.0 0.1 0.0035 17.2 0.1 2.1 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 ORY89928.1 - 0.016 15.0 0.1 0.24 11.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY89928.1 - 0.25 11.5 1.9 3 8.2 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 ORY89929.1 - 7.8e-12 45.2 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY89929.1 - 3.3e-11 43.4 0.0 3.9e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY89929.1 - 2.3e-09 37.5 0.0 3.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY89929.1 - 0.026 14.6 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORY89929.1 - 0.032 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Pinin_SDK_memA PF04696.13 ORY89930.1 - 6.4e-25 87.7 19.2 6.4e-25 87.7 19.2 2.7 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region LMBR1 PF04791.16 ORY89930.1 - 5.3 5.8 8.9 6.2 5.6 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RRM_1 PF00076.22 ORY89931.1 - 4.5e-23 80.9 0.0 1.1e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 ORY89931.1 - 3.4e-20 70.5 0.0 2.1e-05 23.9 0.0 5.7 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat DUF4523 PF15023.6 ORY89931.1 - 9.6e-06 25.5 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 ORY89931.1 - 0.00042 20.1 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 ORY89931.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA-recognition motif FANCI_S2 PF14676.6 ORY89931.1 - 0.083 13.2 2.1 0.45 10.8 0.2 2.9 3 1 0 3 3 3 0 FANCI solenoid 2 CSN5_C PF18323.1 ORY89931.1 - 0.09 13.7 0.8 0.31 12.0 0.0 2.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain 3HCDH PF00725.22 ORY89932.1 - 1.3e-19 70.6 0.0 1.4e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 ORY89933.1 - 7.6e-54 182.3 1.5 9.3e-54 182.0 1.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY89933.1 - 0.00034 21.2 0.3 0.0019 18.8 0.0 2.3 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ribosomal_L38e PF01781.18 ORY89935.1 - 7.1e-36 122.1 4.5 7.9e-36 122.0 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORY89935.1 - 0.0039 17.4 0.1 0.0047 17.1 0.1 1.1 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain CRF PF00473.17 ORY89935.1 - 0.019 15.0 0.4 0.043 13.9 0.4 1.5 1 0 0 1 1 1 0 Corticotropin-releasing factor family CLTH PF10607.9 ORY89936.1 - 1.8e-21 76.5 0.0 2.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY89936.1 - 0.0052 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 LisH HNF-1A_C PF04813.12 ORY89936.1 - 0.015 16.0 0.1 0.032 15.0 0.1 1.5 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Hus1 PF04005.12 ORY89937.1 - 5.6e-40 137.3 0.1 6.7e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein XLF PF09302.11 ORY89937.1 - 0.03 14.5 0.1 0.038 14.2 0.1 1.2 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component zf-CHY PF05495.12 ORY89938.1 - 4.4e-14 52.7 13.2 1.2e-13 51.3 13.2 1.6 1 1 0 1 1 1 1 CHY zinc finger zf_UBZ PF18439.1 ORY89938.1 - 0.0051 16.4 4.4 4.7 6.9 0.2 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-UDP PF14569.6 ORY89938.1 - 0.022 14.9 2.6 0.022 14.9 2.6 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.10 ORY89938.1 - 0.025 14.7 4.3 0.025 14.7 4.3 2.4 2 1 1 3 3 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 ORY89938.1 - 0.045 14.0 7.6 0.4 11.0 1.1 2.5 1 1 1 2 2 2 0 zinc-ribbon DUF4379 PF14311.6 ORY89938.1 - 0.1 13.0 1.2 0.1 13.0 1.2 2.3 1 1 0 2 2 2 0 Probable Zinc-ribbon domain RNA_POL_M_15KD PF02150.16 ORY89938.1 - 0.2 11.5 11.2 1.5 8.7 0.2 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 ORY89938.1 - 0.25 11.3 13.0 1.6 8.8 4.7 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORY89938.1 - 0.47 10.5 11.8 0.15 12.1 2.5 2.4 1 1 2 3 3 3 0 zinc-ribbons NOB1_Zn_bind PF08772.11 ORY89938.1 - 0.76 10.0 9.5 2.6 8.2 9.5 1.9 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2_6 PF13912.6 ORY89938.1 - 0.83 9.7 7.1 0.77 9.8 2.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.19 ORY89938.1 - 0.86 9.6 9.8 4 7.5 9.8 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 ORY89938.1 - 4.9 7.5 12.0 39 4.6 9.1 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 ORY89938.1 - 8.2 6.4 13.0 24 4.9 5.6 3.3 2 1 0 2 2 2 0 zinc-ribbon domain DUF2189 PF09955.9 ORY89939.1 - 0.047 13.9 0.9 0.066 13.5 0.9 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Cdh1_DBD_1 PF18196.1 ORY89939.1 - 0.14 12.4 1.0 0.23 11.8 1.0 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 bZIP_1 PF00170.21 ORY89939.1 - 0.19 11.8 4.1 0.33 11.1 4.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor Neur_chan_memb PF02932.16 ORY89939.1 - 0.37 10.8 3.4 0.51 10.4 3.5 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_125 PF06824.11 ORY89940.1 - 1.2e-159 531.7 0.0 1.3e-159 531.5 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) GH114_assoc PF14741.6 ORY89940.1 - 0.00023 21.4 0.1 0.00049 20.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal glycosyl-hydrolase-114-associated domain RabGAP-TBC PF00566.18 ORY89942.1 - 9.5e-32 110.4 0.0 2.1e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Arrestin_N PF00339.29 ORY89943.1 - 1.7e-12 47.6 0.0 4.4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY89943.1 - 1.3e-08 35.4 0.0 1.5e-06 28.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORY89943.1 - 0.0027 17.0 0.4 0.035 13.3 0.0 2.0 1 1 1 2 2 2 1 Rgp1 LDB19 PF13002.7 ORY89943.1 - 0.09 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like CENP-F_leu_zip PF10473.9 ORY89944.1 - 0.01 15.9 0.9 0.01 15.9 0.9 3.5 4 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RhoGEF PF00621.20 ORY89944.1 - 0.039 14.2 3.4 4.2 7.6 1.2 2.7 2 1 0 2 2 2 0 RhoGEF domain Herpes_UL7 PF01677.16 ORY89944.1 - 0.13 12.0 0.2 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus UL7 like Spectrin PF00435.21 ORY89944.1 - 0.55 10.8 18.8 7.6 7.1 0.6 6.2 5 1 1 6 6 6 0 Spectrin repeat Fzo_mitofusin PF04799.13 ORY89944.1 - 4.2 6.9 11.7 3.8 7.0 0.5 3.7 3 2 0 3 3 3 0 fzo-like conserved region APG6_N PF17675.1 ORY89944.1 - 9.8 6.7 25.9 2.5 8.6 4.5 4.3 3 1 1 4 4 4 0 Apg6 coiled-coil region WD40 PF00400.32 ORY89945.1 - 1.1e-58 193.8 13.2 3e-09 37.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89945.1 - 4.8e-22 78.1 0.0 0.00019 21.7 0.0 5.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY89945.1 - 4.6e-10 39.0 0.3 0.14 11.1 0.0 5.3 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY89945.1 - 2.1e-09 37.2 0.0 0.0023 17.3 0.0 4.5 5 0 0 5 5 5 2 WD40-like domain Nup160 PF11715.8 ORY89945.1 - 3.1e-06 26.1 1.0 0.12 10.9 0.1 4.3 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORY89945.1 - 8.1e-05 21.3 0.6 0.16 10.5 0.1 3.3 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.6 ORY89945.1 - 0.00041 19.8 0.1 1.2 8.4 0.0 3.1 1 1 2 3 3 3 3 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 ORY89945.1 - 0.0058 16.5 0.0 8.9 6.1 0.0 3.3 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Peptidase_S9_N PF02897.15 ORY89945.1 - 0.015 14.1 0.0 1.2 7.8 0.0 3.2 2 2 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain MMS1_N PF10433.9 ORY89945.1 - 0.027 13.1 0.0 0.57 8.7 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term VID27 PF08553.10 ORY89945.1 - 0.028 13.5 0.0 2.9 6.9 0.0 3.2 3 1 1 4 4 4 0 VID27 C-terminal WD40-like domain Gmad1 PF10647.9 ORY89945.1 - 0.063 13.0 0.0 1.2 8.9 0.0 2.5 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 ORY89945.1 - 0.086 12.8 0.1 92 3.2 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Adeno_E1B_19K PF01691.16 ORY89945.1 - 0.1 12.1 0.1 9.8 5.7 0.0 2.7 3 0 0 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen DUF5122 PF17164.4 ORY89945.1 - 0.13 12.6 1.3 31 5.0 0.0 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller CN_hydrolase PF00795.22 ORY89945.1 - 0.17 11.2 0.0 17 4.6 0.0 2.2 1 1 0 2 2 2 0 Carbon-nitrogen hydrolase Proteasome_A_N PF10584.9 ORY89945.1 - 9.7 6.0 10.6 63 3.4 0.0 5.2 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Tup_N PF08581.10 ORY89946.1 - 6e-08 32.9 3.9 7.7e-08 32.5 3.9 1.1 1 0 0 1 1 1 1 Tup N-terminal CEP63 PF17045.5 ORY89946.1 - 0.086 12.7 1.3 0.11 12.4 1.3 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa SET PF00856.28 ORY89947.1 - 0.0021 18.5 3.1 0.006 17.0 0.0 2.7 2 1 0 2 2 2 1 SET domain TERB2 PF15101.6 ORY89947.1 - 0.092 12.8 8.1 0.11 12.5 7.2 1.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 ORY89947.1 - 0.15 12.1 0.3 0.14 12.2 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 ORY89947.1 - 0.74 9.6 14.7 1.1 9.1 14.7 1.2 1 0 0 1 1 1 0 Coilin N-terminus Spt20 PF12090.8 ORY89947.1 - 1.5 8.4 18.0 2 8.0 18.0 1.2 1 0 0 1 1 1 0 Spt20 family Peptidase_S49_N PF08496.10 ORY89947.1 - 3.9 7.5 9.0 7.6 6.6 9.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 ORY89947.1 - 5.7 5.6 8.6 6.9 5.3 8.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 ORY89947.1 - 9.2 7.3 9.5 14 6.7 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Prominin PF05478.11 ORY89948.1 - 1.6 6.6 3.9 1.7 6.5 3.9 1.1 1 0 0 1 1 1 0 Prominin zf-C2H2_jaz PF12171.8 ORY89949.1 - 5.5e-08 32.9 0.2 0.016 15.5 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY89949.1 - 8.9e-07 29.1 0.7 0.00046 20.5 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY89949.1 - 8.8e-06 26.1 5.2 0.021 15.6 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY89949.1 - 1.3e-05 24.8 2.6 0.0014 18.4 0.3 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 ORY89949.1 - 3.7e-05 23.9 8.7 0.0077 16.6 1.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY89949.1 - 0.00016 21.6 4.7 0.0003 20.7 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY89949.1 - 0.0045 17.4 2.5 0.0045 17.4 2.5 2.3 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_2 PF12756.7 ORY89949.1 - 0.068 13.5 2.3 3.6 8.0 0.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 ORY89949.1 - 0.11 12.7 0.5 0.29 11.4 0.5 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 ORY89949.1 - 0.13 12.4 1.3 0.42 10.8 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 ORY89949.1 - 0.31 11.5 2.0 16 6.0 0.3 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 ORY89949.1 - 3.1 7.8 5.0 1.5 8.8 2.3 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Lipase_3 PF01764.25 ORY89950.1 - 8.3e-23 80.8 0.1 2e-21 76.4 0.1 2.3 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY89950.1 - 0.01 16.5 0.1 0.022 15.4 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORY89950.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family G-alpha PF00503.20 ORY89951.1 - 6.2e-110 367.7 0.2 7.3e-110 367.5 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY89951.1 - 7.5e-15 54.8 0.1 9.2e-09 35.0 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY89951.1 - 0.00042 19.8 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY89951.1 - 0.015 15.5 0.0 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY89951.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UCR_UQCRX_QCR9 PF05365.12 ORY89952.1 - 7.8e-28 96.2 3.2 8.5e-28 96.1 3.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like HSF_DNA-bind PF00447.17 ORY89953.1 - 5.7e-13 49.3 0.1 5.8e-13 49.3 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Macoilin PF09726.9 ORY89954.1 - 2 6.9 4.3 2.2 6.8 4.3 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 ORY89954.1 - 5.5 5.1 4.9 5.6 5.1 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EXS PF03124.14 ORY89955.1 - 9.7e-99 330.8 21.3 1.1e-98 330.6 21.3 1.0 1 0 0 1 1 1 1 EXS family Transketolase_N PF00456.21 ORY89956.1 - 1e-156 521.1 0.1 1.4e-156 520.6 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY89956.1 - 3.7e-43 147.3 0.0 1.9e-42 144.9 0.0 2.2 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY89956.1 - 1.5e-13 50.7 0.0 7.8e-13 48.4 0.0 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY89956.1 - 4.8e-07 29.3 0.0 9.1e-06 25.1 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ORY89956.1 - 0.00082 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase PF00069.25 ORY89957.1 - 1.2e-72 244.5 0.1 1.4e-72 244.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89957.1 - 6.6e-35 120.6 0.1 8.9e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY89957.1 - 3.1e-09 36.6 0.1 4e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 ORY89957.1 - 0.00032 21.4 1.7 0.00058 20.5 0.3 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 ORY89957.1 - 0.00049 19.8 0.5 0.31 10.6 0.0 2.5 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Ribosomal_S14 PF00253.21 ORY89957.1 - 0.0043 16.8 0.0 0.083 12.7 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Haspin_kinase PF12330.8 ORY89957.1 - 0.011 14.7 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY89957.1 - 0.021 13.6 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORY89957.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myosin_head PF00063.21 ORY89958.1 - 5.3e-268 890.8 0.5 7.9e-268 890.2 0.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY89958.1 - 1.2e-27 96.3 2.4 1.2e-27 96.3 2.4 3.1 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 ORY89958.1 - 2.4e-11 42.4 36.5 5e-05 22.7 0.2 7.5 8 0 0 8 8 7 4 IQ calmodulin-binding motif Spc7 PF08317.11 ORY89958.1 - 0.0032 16.4 26.4 0.0081 15.1 26.4 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_22 PF13401.6 ORY89958.1 - 0.019 15.3 0.0 0.13 12.6 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY89958.1 - 0.066 13.6 1.1 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 ORY89958.1 - 0.095 12.6 1.8 2 8.3 0.0 3.1 3 0 0 3 3 3 0 NACHT domain Retrotran_gag_3 PF14244.6 ORY89958.1 - 0.18 11.7 0.1 0.47 10.3 0.1 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4795 PF16043.5 ORY89958.1 - 0.31 10.6 20.0 1.4 8.5 20.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TolA_bind_tri PF16331.5 ORY89958.1 - 0.72 10.0 10.9 1.1 9.4 6.0 3.3 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 ORY89958.1 - 4.3 7.4 16.8 7.3 6.7 9.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORY89958.1 - 4.9 7.6 17.3 4 7.9 6.5 3.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Aminotran_1_2 PF00155.21 ORY89959.1 - 1.2e-41 143.1 0.0 1.5e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY89959.1 - 1.5e-06 27.1 0.0 2.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ORY89959.1 - 0.0054 16.1 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase AAA PF00004.29 ORY89960.1 - 8.4e-17 61.8 0.0 2.5e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY89960.1 - 8.1e-06 26.3 0.0 2e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY89960.1 - 0.0019 18.2 0.0 0.008 16.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY89960.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ORY89960.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 ORY89960.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 ORY89960.1 - 0.042 13.6 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY89960.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 ORY89960.1 - 0.09 12.6 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.22 ORY89960.1 - 0.099 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 ORY89960.1 - 0.11 12.7 0.0 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY89960.1 - 0.17 11.1 0.0 1.3 8.2 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) RhoGAP-FF1 PF16512.5 ORY89961.1 - 0.027 15.1 0.0 0.036 14.8 0.0 1.2 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Promethin PF16015.5 ORY89962.1 - 4.3e-05 23.4 12.0 6.4e-05 22.8 12.0 1.3 1 0 0 1 1 1 1 Promethin Ctr PF04145.15 ORY89962.1 - 0.0032 18.1 0.3 1.3 9.7 0.2 2.1 1 1 0 2 2 2 2 Ctr copper transporter family DUF1772 PF08592.11 ORY89962.1 - 0.13 12.6 5.8 0.18 12.1 5.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Zn_clus PF00172.18 ORY89963.1 - 2.3e-08 34.0 12.8 2.3e-08 34.0 12.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4381 PF14316.6 ORY89963.1 - 0.067 13.4 0.1 0.14 12.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) MAP65_ASE1 PF03999.12 ORY89963.1 - 1.1 7.9 7.0 1.4 7.6 7.0 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PRRSV_2b PF07069.11 ORY89964.1 - 5.3 7.6 14.2 0.084 13.4 5.1 2.7 2 1 1 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b PWI PF01480.17 ORY89965.1 - 4.4e-30 103.8 0.1 8e-30 103.0 0.1 1.4 1 0 0 1 1 1 1 PWI domain F-box-like PF12937.7 ORY89966.1 - 0.0061 16.4 0.5 0.018 14.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like DUF2624 PF11116.8 ORY89966.1 - 0.17 12.8 0.3 14 6.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2624) GCM PF03615.15 ORY89967.1 - 0.13 12.1 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 GCM motif protein F-box PF00646.33 ORY89968.1 - 0.0013 18.5 0.5 0.0066 16.3 0.5 2.3 1 0 0 1 1 1 1 F-box domain BRAP2 PF07576.12 ORY89969.1 - 2.9e-25 88.4 0.0 6.1e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 ORY89969.1 - 1.8e-18 66.6 4.3 6.2e-18 64.9 4.3 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 ORY89969.1 - 0.001 19.3 7.7 0.001 19.3 7.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY89969.1 - 0.014 15.2 15.3 0.46 10.4 5.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SPX PF03105.19 ORY89969.1 - 0.033 14.1 14.0 0.092 12.6 7.5 2.1 2 0 0 2 2 2 0 SPX domain ISG65-75 PF11727.8 ORY89969.1 - 0.044 13.0 6.0 0.073 12.3 6.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1664 PF07889.12 ORY89969.1 - 0.1 12.6 8.1 0.084 12.9 6.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 ORY89969.1 - 0.95 9.3 12.4 0.06 13.1 3.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 ORY89969.1 - 1.1 9.5 12.4 0.46 10.7 2.0 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LPP PF04728.13 ORY89969.1 - 3.5 8.1 6.6 0.71 10.3 0.3 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper APG6_N PF17675.1 ORY89969.1 - 3.9 8.0 18.6 6.5 7.3 18.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 ORY89969.1 - 7.8 6.5 22.1 0.19 11.8 2.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 ORY89969.1 - 8 5.6 6.7 13 5.0 6.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein zf-C3HC4_2 PF13923.6 ORY89969.1 - 8.4 6.3 17.7 0.036 13.9 7.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.23 ORY89970.1 - 3.6e-22 78.6 0.0 6.2e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY89970.1 - 4.7e-09 36.4 0.0 8.5e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ORY89970.1 - 2.8e-06 27.0 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 ORY89970.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 ORY89970.1 - 3.8e-05 23.8 0.1 0.017 15.2 0.1 2.5 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 ORY89970.1 - 0.00056 20.1 0.0 0.00098 19.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY89970.1 - 0.0013 18.3 0.0 0.44 10.0 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 ORY89970.1 - 0.0018 18.3 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 ORY89970.1 - 0.01 15.1 0.2 0.081 12.2 0.1 2.3 2 1 0 2 2 2 0 Septin NB-ARC PF00931.22 ORY89970.1 - 0.018 14.2 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 ORY89970.1 - 0.047 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AIG1 PF04548.16 ORY89970.1 - 0.19 11.0 0.1 0.6 9.4 0.1 1.9 1 1 0 1 1 1 0 AIG1 family Ras PF00071.22 ORY89970.1 - 0.2 11.2 0.0 0.59 9.7 0.0 1.7 2 0 0 2 2 2 0 Ras family WD40 PF00400.32 ORY89971.1 - 1.4e-17 63.8 3.1 6.2e-06 26.8 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89971.1 - 7e-07 29.5 0.0 7.5 6.9 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 ORY89971.1 - 0.0016 17.8 0.0 0.0035 16.6 0.0 1.5 1 1 1 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Marek_SORF3 PF07153.11 ORY89971.1 - 0.0022 17.3 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Marek's disease-like virus SORF3 protein Nucleoporin_N PF08801.11 ORY89971.1 - 0.054 12.2 0.1 31 3.1 0.0 3.0 1 1 1 3 3 3 0 Nup133 N terminal like PQQ_2 PF13360.6 ORY89971.1 - 0.072 12.7 0.1 0.39 10.2 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain DcpS_C PF11969.8 ORY89972.1 - 3.1e-30 105.0 0.0 5.5e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 ORY89972.1 - 6.7e-24 84.7 0.0 1.1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Lin-8 PF03353.15 ORY89973.1 - 1.6 8.2 22.7 0.031 13.8 13.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FYRN PF05964.14 ORY89974.1 - 2.4e-21 75.3 0.5 7e-21 73.8 0.5 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY89974.1 - 2.9e-13 49.8 0.0 1.6e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 F/Y rich C-terminus Pkinase PF00069.25 ORY89975.1 - 3.2e-74 249.6 0.0 4.9e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89975.1 - 7e-39 133.7 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY89975.1 - 7.3e-06 26.1 0.3 0.0007 19.6 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY89975.1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 ORY89975.1 - 0.023 14.3 1.0 0.051 13.1 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 ORY89975.1 - 0.075 12.4 0.6 0.16 11.3 0.6 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-4CXXC_R1 PF10497.9 ORY89976.1 - 5.8e-06 26.4 20.1 3.1e-05 24.1 16.4 3.0 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_UBOX PF13445.6 ORY89976.1 - 0.00083 19.3 1.2 0.00083 19.3 1.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY89976.1 - 0.0022 17.8 1.6 0.0022 17.8 1.6 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY89976.1 - 0.49 10.3 13.9 0.066 13.1 8.3 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY89976.1 - 0.88 9.6 13.6 0.049 13.6 6.7 2.6 2 1 0 2 2 2 0 zinc-RING finger domain YkyA PF10368.9 ORY89976.1 - 2.2 7.9 5.9 11 5.7 2.4 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein MetJ PF01340.20 ORY89977.1 - 0.02 14.8 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Met Apo-repressor, MetJ zinc-ribbons_6 PF07191.12 ORY89978.1 - 0.24 11.4 11.2 0.74 9.8 5.7 2.3 2 1 1 3 3 3 0 zinc-ribbons DUF2797 PF10977.8 ORY89978.1 - 1.3 8.9 5.5 1.6 8.6 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) MMM1 PF10296.9 ORY89979.1 - 7e-12 45.0 5.7 1.7e-10 40.5 0.5 3.5 3 2 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 Sporozoite_P67 PF05642.11 ORY89979.1 - 0.11 10.6 9.2 0.15 10.1 9.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UEV PF05743.13 ORY89980.1 - 7e-38 129.2 0.6 7e-38 129.2 0.6 1.7 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 ORY89980.1 - 1.2e-25 89.2 0.2 3.4e-25 87.7 0.2 1.8 1 0 0 1 1 1 1 Vps23 core domain Prefoldin PF02996.17 ORY89980.1 - 0.1 12.5 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit SPX PF03105.19 ORY89980.1 - 0.17 11.7 1.3 0.24 11.3 1.3 1.1 1 0 0 1 1 1 0 SPX domain Pro_isomerase PF00160.21 ORY89981.1 - 2.4e-42 144.9 0.2 8.5e-42 143.1 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.23 ORY89982.1 - 7.6e-19 67.2 0.5 1.4e-18 66.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY89982.1 - 3.5e-05 23.5 0.9 6.5e-05 22.7 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY89982.1 - 0.0032 18.0 0.2 0.0032 18.0 0.2 3.6 2 1 0 2 2 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY89982.1 - 0.0041 17.2 0.0 0.0041 17.2 0.0 2.8 2 1 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 ORY89982.1 - 0.016 15.2 1.5 0.088 12.9 1.5 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain GREB1 PF15782.5 ORY89982.1 - 0.032 11.4 16.7 0.052 10.7 16.7 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PA26 PF04636.13 ORY89982.1 - 0.19 10.6 8.3 0.34 9.8 8.3 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Spore_coat_CotO PF14153.6 ORY89982.1 - 0.46 10.4 17.1 1 9.2 17.1 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Menin PF05053.13 ORY89982.1 - 0.92 7.8 8.8 1.8 6.8 8.8 1.6 1 0 0 1 1 1 0 Menin SAPS PF04499.15 ORY89982.1 - 0.93 8.2 11.9 1.1 8.0 10.8 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SKA1 PF07160.12 ORY89982.1 - 1.7 8.4 12.9 24 4.7 11.7 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 RR_TM4-6 PF06459.12 ORY89982.1 - 2.5 7.8 17.7 6.6 6.5 17.7 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FancD2 PF14631.6 ORY89982.1 - 6.5 4.0 10.1 37 1.5 9.1 1.9 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease Raftlin PF15250.6 ORY89982.1 - 7.1 5.3 15.1 14 4.3 15.1 1.4 1 0 0 1 1 1 0 Raftlin ALO PF04030.14 ORY89984.1 - 9.1e-76 255.1 1.9 1.4e-75 254.5 1.9 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ORY89984.1 - 1e-29 103.0 0.2 1.5e-29 102.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_5 PF00941.21 ORY89984.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase EphA2_TM PF14575.6 ORY89985.1 - 0.089 13.7 0.0 0.2 12.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_7_1 PF16081.5 ORY89985.1 - 0.18 11.9 1.8 0.27 11.4 1.2 1.5 1 1 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Adeno_E3_CR2 PF02439.15 ORY89985.1 - 0.59 9.9 3.1 0.96 9.3 3.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CDC73_C PF05179.14 ORY89986.1 - 1.9e-47 160.9 2.1 2.7e-47 160.4 0.9 1.8 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 ORY89986.1 - 1.5e-12 47.5 1.6 6e-12 45.5 0.9 1.9 1 1 1 2 2 2 1 Paf1 complex subunit CDC73 N-terminal Inhibitor_I9 PF05922.16 ORY89990.1 - 0.0019 18.8 0.0 1.4 9.6 0.1 2.6 2 1 0 2 2 2 2 Peptidase inhibitor I9 Inhibitor_I9 PF05922.16 ORY89991.1 - 1e-07 32.5 0.1 1.8e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 CNH PF00780.22 ORY89992.1 - 4.2e-62 210.3 0.0 8.2e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY89992.1 - 3.8e-39 134.8 1.8 6.8e-39 134.0 1.8 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY89992.1 - 8.7e-34 116.5 0.0 8.7e-34 116.5 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain DEP PF00610.21 ORY89992.1 - 1.1e-14 54.3 0.0 2.7e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 ORY89992.1 - 1.9e-05 25.1 0.1 0.025 15.1 0.1 3.5 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 ORY89992.1 - 0.00056 19.7 5.7 0.0024 17.7 0.1 3.8 3 1 0 3 3 3 1 Pleckstrin homology domain PH_16 PF17838.1 ORY89992.1 - 0.0067 16.3 0.2 0.024 14.5 0.1 1.9 2 0 0 2 2 2 1 PH domain SUIM_assoc PF16619.5 ORY89992.1 - 6.1 7.0 16.4 0.25 11.4 2.4 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Inhibitor_I9 PF05922.16 ORY89993.1 - 0.00041 21.0 0.3 0.0011 19.6 0.3 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 Glyoxalase_2 PF12681.7 ORY89993.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.0 1 0 0 1 1 1 0 Glyoxalase-like domain Inhibitor_I9 PF05922.16 ORY89994.1 - 0.018 15.7 0.9 0.034 14.8 0.9 1.4 1 1 0 1 1 1 0 Peptidase inhibitor I9 ERF PF04404.12 ORY89994.1 - 0.044 13.6 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 ERF superfamily CNH PF00780.22 ORY89995.1 - 2.9e-57 194.4 0.0 7.3e-57 193.1 0.0 1.6 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 ORY89995.1 - 3.3e-36 125.2 0.9 6.6e-36 124.2 0.1 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 ORY89995.1 - 6.9e-22 78.0 0.1 1.9e-21 76.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY89995.1 - 0.018 15.5 0.1 0.22 12.0 0.0 2.8 2 1 0 2 2 2 0 PH domain PH_16 PF17838.1 ORY89995.1 - 0.039 13.8 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 PH domain DUF3439 PF11921.8 ORY89995.1 - 6.1 6.8 8.7 18 5.3 8.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S2 PF00318.20 ORY89996.1 - 7.7e-25 87.4 0.1 2.2e-13 49.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORY89996.1 - 1.5e-08 35.8 14.4 2.9e-08 34.9 14.4 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Thioredoxin PF00085.20 ORY89997.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin HLH PF00010.26 ORY89998.1 - 6.1e-14 51.7 1.9 1.1e-13 50.9 1.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Symplekin_C PF12295.8 ORY89998.1 - 0.034 14.2 0.1 0.066 13.3 0.1 1.5 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal ThrE PF06738.12 ORY89998.1 - 0.5 9.7 2.8 0.6 9.4 0.5 1.9 2 0 0 2 2 2 0 Putative threonine/serine exporter Prothymosin PF03247.14 ORY89998.1 - 2 8.9 17.8 0.18 12.3 12.5 1.9 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF1754 PF08555.10 ORY89998.1 - 7.9 7.4 21.1 51 4.7 0.2 2.7 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PLA2_B PF01735.18 ORY89999.1 - 0.12 10.8 0.1 0.23 9.8 0.1 1.4 1 0 0 1 1 1 0 Lysophospholipase catalytic domain YabA PF06156.13 ORY89999.1 - 0.52 11.0 4.5 0.63 10.7 0.5 2.9 2 1 1 3 3 3 0 Initiation control protein YabA GCN5L1 PF06320.13 ORY89999.1 - 0.73 10.0 6.6 2.2 8.5 6.6 1.8 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Ribosomal_60s PF00428.19 ORY89999.1 - 1.1 9.9 5.1 3 8.5 5.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Chorion_2 PF03964.15 ORY89999.1 - 2.6 8.9 7.6 1.4 9.8 3.6 2.7 2 1 0 2 2 2 0 Chorion family 2 Polysacc_deac_1 PF01522.21 ORY90000.1 - 1.1e-31 109.3 0.0 1.8e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY90000.1 - 2.9e-08 33.3 0.2 9.8e-08 31.6 0.1 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORY90000.1 - 0.00015 21.5 0.4 0.00022 20.9 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) AAA_31 PF13614.6 ORY90000.1 - 0.031 14.2 0.1 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 ORY90001.1 - 1.1e-55 188.8 0.0 2.1e-55 187.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90001.1 - 1.8e-21 76.6 0.0 2.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 ORY90001.1 - 9.9e-08 32.0 0.1 0.072 13.1 0.0 4.2 3 1 0 4 4 4 2 PAS fold APH PF01636.23 ORY90001.1 - 2.6e-06 27.6 1.5 0.00054 20.0 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY90001.1 - 6.8e-06 25.1 0.0 9.9e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY90001.1 - 3.8e-05 23.1 0.0 8.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY90001.1 - 0.00033 19.7 0.0 0.0005 19.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PAS_9 PF13426.7 ORY90001.1 - 0.00051 20.3 0.0 0.48 10.7 0.0 3.6 3 1 0 3 3 3 1 PAS domain RIO1 PF01163.22 ORY90001.1 - 0.0014 18.2 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 ORY90001.1 - 0.0024 17.3 0.0 0.0052 16.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PAS_4 PF08448.10 ORY90001.1 - 0.025 14.8 0.0 8.5 6.7 0.0 3.2 3 0 0 3 3 3 0 PAS fold FTA2 PF13095.6 ORY90001.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Arrestin_C PF02752.22 ORY90002.1 - 4.2e-20 72.6 0.1 1.1e-14 55.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY90002.1 - 4.6e-09 36.5 0.2 1.6e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY90002.1 - 0.0055 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like cPLA2_C2 PF18695.1 ORY90002.1 - 0.0063 16.5 0.2 0.015 15.3 0.2 1.7 1 1 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain Rgp1 PF08737.10 ORY90002.1 - 0.0066 15.7 0.5 0.47 9.6 0.3 2.2 2 0 0 2 2 2 2 Rgp1 zf-C3HC4 PF00097.25 ORY90003.1 - 3.2e-09 36.5 10.2 5.5e-09 35.8 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY90003.1 - 1.6e-08 34.3 9.3 2.5e-08 33.6 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY90003.1 - 3.6e-08 33.6 11.4 5.9e-08 32.9 11.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY90003.1 - 6e-08 32.4 6.1 1e-07 31.7 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY90003.1 - 8.9e-06 25.6 5.8 8.9e-06 25.6 5.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY90003.1 - 7.5e-05 22.9 11.4 0.00029 21.0 11.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY90003.1 - 0.00023 21.1 9.8 0.00037 20.4 9.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 ORY90003.1 - 0.00048 20.1 3.6 0.00089 19.2 3.6 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 ORY90003.1 - 0.00098 18.9 10.2 0.0073 16.1 10.3 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY90003.1 - 0.0045 17.1 8.7 0.016 15.3 8.7 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 ORY90003.1 - 0.27 11.4 3.7 0.75 10.0 3.7 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 ORY90003.1 - 0.82 9.8 6.0 2.8 8.1 6.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger JUPITER PF17054.5 ORY90003.1 - 6.2 6.2 10.3 9.1 5.6 10.3 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Macoilin PF09726.9 ORY90003.1 - 9.9 4.6 8.2 14 4.1 8.2 1.1 1 0 0 1 1 1 0 Macoilin family SAP30_Sin3_bdg PF13867.6 ORY90004.1 - 3.5e-18 65.7 0.2 5.1e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ PF00226.31 ORY90005.1 - 4.1e-25 87.7 5.0 7e-25 86.9 5.0 1.4 1 0 0 1 1 1 1 DnaJ domain Cyclin PF08613.11 ORY90006.1 - 7.5e-36 123.9 0.1 7.5e-36 123.9 0.1 2.2 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY90006.1 - 1.6e-06 27.9 0.1 2.6e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4630 PF15443.6 ORY90006.1 - 0.0087 16.2 1.4 0.013 15.7 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4630) Pneumo_att_G PF05539.11 ORY90006.1 - 6 6.4 14.3 8.4 5.9 14.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G zf-Tim10_DDP PF02953.15 ORY90007.1 - 2.5e-19 68.7 3.0 3e-19 68.4 3.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 ORY90007.1 - 0.032 13.9 3.7 0.11 12.1 3.5 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.9 ORY90007.1 - 0.2 11.7 0.4 0.2 11.7 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Peptidase_M16 PF00675.20 ORY90009.1 - 4.5e-55 185.7 0.7 2.1e-53 180.3 0.3 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY90009.1 - 4e-40 137.8 0.0 6.2e-39 133.9 0.0 2.6 3 0 0 3 3 3 1 Peptidase M16 inactive domain Nucleo_P87 PF07267.11 ORY90009.1 - 0.032 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Acetyltransf_1 PF00583.25 ORY90010.1 - 6.7e-10 39.2 0.0 8.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY90010.1 - 1.6e-08 34.5 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY90010.1 - 2.2e-08 34.4 0.0 3.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY90010.1 - 0.0084 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORY90010.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 ORY90010.1 - 0.063 13.3 0.0 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 ORY90011.1 - 3.7e-24 85.3 62.3 2.1e-17 63.1 36.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY90011.1 - 2.6e-09 36.1 16.5 2.6e-09 36.1 16.5 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein Phage_holin_2_4 PF16082.5 ORY90011.1 - 3.8 7.3 7.0 16 5.3 2.1 3.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 ORY90012.1 - 3e-28 98.8 55.0 3.9e-17 62.2 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PSS PF03034.15 ORY90012.1 - 0.015 15.0 0.5 0.027 14.2 0.5 1.3 1 0 0 1 1 1 0 Phosphatidyl serine synthase DUF2070 PF09843.9 ORY90012.1 - 2.3 6.4 8.4 3.7 5.7 8.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FA_hydroxylase PF04116.13 ORY90013.1 - 7.1e-25 87.9 26.2 8.8e-25 87.6 23.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NMT1 PF09084.11 ORY90015.1 - 1.6e-70 237.4 0.0 2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ORY90015.1 - 0.003 17.3 0.0 2.4 7.8 0.0 2.6 3 0 0 3 3 3 2 NMT1-like family Ribosomal_L7Ae PF01248.26 ORY90016.1 - 3.3e-25 87.6 0.0 4e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EF_TS PF00889.19 ORY90017.1 - 7.1e-36 123.8 0.1 4e-28 98.4 0.0 2.4 1 1 1 2 2 2 2 Elongation factor TS HBS1_N PF08938.10 ORY90017.1 - 0.044 14.1 1.0 0.28 11.5 0.2 2.3 2 0 0 2 2 2 0 HBS1 N-terminus Acetyltransf_10 PF13673.7 ORY90018.1 - 1.2e-09 38.2 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY90018.1 - 5.6e-08 33.0 0.0 7.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY90018.1 - 3.4e-07 30.6 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY90018.1 - 0.033 14.2 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein OrfB_Zn_ribbon PF07282.11 ORY90021.1 - 2.8e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY90022.1 - 0.003 17.5 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HEAT_2 PF13646.6 ORY90023.1 - 0.0003 21.1 10.4 0.048 14.0 2.5 2.9 3 1 0 3 3 3 2 HEAT repeats NRDE-2 PF08424.10 ORY90024.1 - 0.036 13.2 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Med11 PF10280.9 ORY90025.1 - 1.5e-09 38.5 0.1 1.5e-09 38.5 0.1 1.7 2 0 0 2 2 2 1 Mediator complex protein Guanylate_cyc PF00211.20 ORY90025.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain MgsA_C PF12002.8 ORY90026.1 - 3e-61 206.2 0.1 4.7e-61 205.6 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 ORY90026.1 - 2.1e-22 79.2 0.0 5.6e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 ORY90026.1 - 4.6e-18 65.9 0.0 8.1e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY90026.1 - 3.1e-14 53.0 0.0 4.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY90026.1 - 8.6e-08 32.3 0.0 2.9e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY90026.1 - 2.4e-07 31.3 1.1 0.0044 17.4 0.0 3.4 1 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 ORY90026.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORY90026.1 - 1.6e-06 27.9 0.0 6.7e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 ORY90026.1 - 5.3e-05 22.7 0.1 0.081 12.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 ORY90026.1 - 0.00012 21.4 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 ORY90026.1 - 0.00026 21.1 0.0 0.00071 19.7 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_2 PF07724.14 ORY90026.1 - 0.00049 20.3 0.0 0.0009 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY90026.1 - 0.0012 19.1 0.4 0.016 15.5 0.4 2.3 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORY90026.1 - 0.0013 18.6 0.1 0.0032 17.4 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 ORY90026.1 - 0.0017 18.7 0.4 0.39 11.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY90026.1 - 0.0025 18.4 0.0 0.0053 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY90026.1 - 0.0026 18.1 0.0 0.0086 16.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase ATPase_2 PF01637.18 ORY90026.1 - 0.0034 17.3 0.3 1.9 8.3 0.2 2.4 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 ORY90026.1 - 0.0037 17.0 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ORY90026.1 - 0.0042 16.8 0.1 0.017 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain zf-WRNIP1_ubi PF18279.1 ORY90026.1 - 0.0051 17.3 0.5 0.045 14.4 1.3 2.3 2 0 0 2 2 1 1 Werner helicase-interacting protein 1 ubiquitin-binding domain ABC_tran PF00005.27 ORY90026.1 - 0.0053 17.3 0.1 0.016 15.8 0.0 1.9 2 0 0 2 2 1 1 ABC transporter TniB PF05621.11 ORY90026.1 - 0.0055 16.1 0.0 0.074 12.5 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein NB-ARC PF00931.22 ORY90026.1 - 0.011 14.9 0.0 0.039 13.1 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 ORY90026.1 - 0.014 15.4 0.4 1.5 8.8 0.3 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 ORY90026.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.12 ORY90026.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 ORY90026.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRAF6_Z2 PF18048.1 ORY90026.1 - 0.031 14.4 6.3 0.89 9.7 4.3 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 AAA_24 PF13479.6 ORY90026.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 ORY90026.1 - 0.041 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ATP-synt_ab PF00006.25 ORY90026.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.22 ORY90026.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase Zeta_toxin PF06414.12 ORY90026.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 ORY90026.1 - 0.1 12.8 0.3 0.23 11.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY90026.1 - 0.15 11.5 0.0 0.6 9.6 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region SAC3_GANP PF03399.16 ORY90026.1 - 0.4 10.0 2.7 11 5.2 0.0 2.2 2 0 0 2 2 2 0 SAC3/GANP family YkpC PF17447.2 ORY90026.1 - 6 7.9 5.5 3.3 8.7 2.3 2.4 2 0 0 2 2 1 0 Uncharacterized YkpC-like SIKE PF05769.11 ORY90027.1 - 1.2e-07 31.9 13.9 1.9e-07 31.2 13.9 1.5 1 1 0 1 1 1 1 SIKE family DUF2344 PF10105.9 ORY90027.1 - 0.061 13.2 1.0 0.12 12.2 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) HALZ PF02183.18 ORY90027.1 - 0.11 12.8 11.4 0.93 9.8 0.1 4.5 4 1 0 4 4 4 0 Homeobox associated leucine zipper Chrome_Resist PF09828.9 ORY90027.1 - 0.19 12.2 3.6 0.8 10.2 0.3 2.6 2 1 1 3 3 3 0 Chromate resistance exported protein YabA PF06156.13 ORY90027.1 - 0.61 10.8 17.2 3.7 8.2 3.7 3.8 2 1 2 4 4 4 0 Initiation control protein YabA DUF4250 PF14056.6 ORY90027.1 - 0.83 9.7 7.8 0.67 9.9 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) SpecificRecomb PF10136.9 ORY90027.1 - 3 6.0 9.4 4 5.6 8.7 1.5 1 1 0 1 1 1 0 Site-specific recombinase Lectin_N PF03954.14 ORY90027.1 - 5.1 6.9 10.1 2.5 7.9 3.4 3.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FUSC PF04632.12 ORY90027.1 - 6 5.3 15.7 7.5 4.9 15.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLASP_N PF12348.8 ORY90028.1 - 8.5e-19 68.0 1.3 1.1e-18 67.7 1.3 1.0 1 0 0 1 1 1 1 CLASP N terminal HEAT_EZ PF13513.6 ORY90028.1 - 0.00086 19.8 0.0 0.043 14.3 0.0 2.7 1 1 1 2 2 2 2 HEAT-like repeat DUF3437 PF11919.8 ORY90028.1 - 0.0031 17.4 3.5 0.053 13.4 0.1 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 ORY90028.1 - 0.019 15.2 0.1 3.1 8.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 ORY90028.1 - 0.023 15.1 0.2 0.2 12.1 0.0 2.4 2 1 0 2 2 2 0 HEAT repeats Cnd1 PF12717.7 ORY90028.1 - 0.032 14.3 0.0 0.24 11.4 0.0 2.1 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FUSC PF04632.12 ORY90028.1 - 0.15 10.6 2.9 0.99 7.9 1.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family DHHC PF01529.20 ORY90029.1 - 6.5e-35 120.2 11.8 6.5e-35 120.2 11.8 2.4 2 1 1 3 3 3 1 DHHC palmitoyltransferase DNA_pol_E_B PF04042.16 ORY90030.1 - 1.4e-45 155.2 0.0 2.2e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ORY90030.1 - 1.1e-36 125.8 0.0 2.1e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Na_Ca_ex PF01699.24 ORY90033.1 - 3.8e-46 156.8 41.6 1.7e-26 93.0 14.3 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF908 PF06012.12 ORY90033.1 - 2.2 7.6 7.1 3.6 6.9 7.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Glyco_hydro_47 PF01532.20 ORY90035.1 - 2.5e-117 392.6 0.0 3.7e-117 392.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 ORY90037.1 - 1.2e-05 25.3 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PA domain YitT_membrane PF02588.15 ORY90038.1 - 0.036 13.4 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Pkinase PF00069.25 ORY90039.1 - 5.7e-67 225.9 0.0 7.6e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90039.1 - 1.7e-38 132.4 0.0 2.3e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY90039.1 - 5.9e-07 29.1 0.0 9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY90039.1 - 9.7e-05 21.8 0.1 0.0002 20.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY90039.1 - 0.00046 19.1 0.0 0.00072 18.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY90039.1 - 0.0034 17.3 1.6 0.0086 16.0 1.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family MucBP_2 PF17965.1 ORY90039.1 - 0.13 12.8 0.2 0.3 11.7 0.2 1.6 1 0 0 1 1 1 0 Mucin binding domain Lipase_GDSL_2 PF13472.6 ORY90040.1 - 8.1e-30 104.5 0.1 1.2e-29 104.0 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY90040.1 - 1.7e-23 83.6 0.0 2.1e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 ORY90040.1 - 0.039 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX SET PF00856.28 ORY90041.1 - 1.2e-20 74.6 0.5 1.2e-20 74.6 0.5 3.1 2 1 0 2 2 2 1 SET domain N-SET PF11764.8 ORY90041.1 - 9.5e-11 42.1 1.5 4.1e-07 30.3 0.3 6.4 5 2 3 8 8 8 2 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 ORY90041.1 - 8.2e-10 38.4 0.0 1.1e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 ORY90041.1 - 1.4e-07 31.0 0.2 6.2e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated IBR PF01485.21 ORY90041.1 - 0.27 11.5 1.4 0.57 10.5 1.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Myb_DNA-bind_5 PF13873.6 ORY90045.1 - 0.022 14.8 0.4 0.022 14.8 0.4 1.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Oxidored_molyb PF00174.19 ORY90045.1 - 0.025 14.2 0.3 0.038 13.6 0.3 1.3 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain PDDEXK_7 PF04411.12 ORY90331.1 - 0.041 13.8 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Glyoxalase_2 PF12681.7 ORY90331.1 - 0.06 13.3 0.3 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Glyoxalase-like domain DEAD PF00270.29 ORY90333.1 - 1.7e-42 145.1 0.0 4.6e-42 143.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY90333.1 - 6.8e-23 81.1 0.1 3.3e-22 78.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY90333.1 - 1.3e-07 31.7 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY90333.1 - 2.1e-05 23.9 0.0 4.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 ORY90333.1 - 0.00029 21.1 0.6 0.051 13.9 0.7 3.0 2 1 0 2 2 2 1 AAA domain SecA_DEAD PF07517.14 ORY90333.1 - 0.0047 16.3 0.0 0.018 14.4 0.0 1.9 1 1 0 1 1 1 1 SecA DEAD-like domain DUF763 PF05559.11 ORY90333.1 - 0.37 9.9 1.5 0.38 9.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF763) DUF3512 PF12024.8 ORY90334.1 - 6.2e-07 29.1 0.9 9.4e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) SRR1 PF07985.12 ORY90335.1 - 5.9e-16 58.3 0.1 1.1e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 SRR1 Ldh_1_N PF00056.23 ORY90336.1 - 1.1e-19 71.0 0.0 1.6e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY90336.1 - 0.00018 21.5 0.6 0.0003 20.7 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY90336.1 - 0.0025 18.4 0.1 0.0061 17.1 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 ORY90336.1 - 0.0026 17.4 0.1 0.0042 16.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY90336.1 - 0.0063 15.8 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY90336.1 - 0.011 16.3 0.2 0.03 14.9 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_C PF02866.18 ORY90336.1 - 0.015 15.3 0.1 0.043 13.8 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_7 PF13241.6 ORY90336.1 - 0.02 15.3 0.1 0.15 12.5 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ORY90336.1 - 0.028 14.7 0.2 0.051 13.8 0.2 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 ORY90336.1 - 0.042 14.1 0.2 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 ORY90336.1 - 0.053 13.5 0.6 0.18 11.8 0.6 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORY90336.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Asp PF00026.23 ORY90337.1 - 2.4e-80 270.3 0.0 2.7e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY90337.1 - 3.4e-17 63.3 2.9 9e-13 48.8 2.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY90337.1 - 2.1e-06 27.6 0.0 0.00081 19.2 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY90337.1 - 3.4e-05 24.4 0.1 0.16 12.6 0.0 3.2 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY90337.1 - 0.00021 21.8 0.0 0.052 14.1 0.0 2.9 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease DUF5633 PF18656.1 ORY90337.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5633) EMC3_TMCO1 PF01956.16 ORY90338.1 - 1.8e-51 174.3 1.6 1.8e-51 174.3 1.6 1.4 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like DUF975 PF06161.11 ORY90338.1 - 0.01 15.7 2.7 0.012 15.5 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF975) DUF2208 PF09973.9 ORY90338.1 - 0.067 12.8 0.4 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF350 PF03994.14 ORY90338.1 - 0.14 12.3 1.1 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Lactamase_B_2 PF12706.7 ORY90339.1 - 1.9e-14 53.6 0.3 5.2e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY90339.1 - 1.4e-06 28.5 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 ORY90339.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease HALZ PF02183.18 ORY90339.1 - 0.013 15.7 8.7 0.017 15.3 2.8 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Atg14 PF10186.9 ORY90339.1 - 0.38 9.8 9.6 0.74 8.8 9.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PKcGMP_CC PF16808.5 ORY90339.1 - 0.41 10.6 5.5 0.7 9.8 0.8 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 ORY90339.1 - 1.4 9.1 12.4 0.61 10.3 5.4 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Sugar_tr PF00083.24 ORY90340.1 - 8.8e-111 370.9 19.0 1e-110 370.8 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY90340.1 - 8.5e-19 67.7 40.0 5.6e-13 48.5 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.6 ORY90340.1 - 0.88 9.1 3.8 0.69 9.4 1.7 1.9 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Usp PF00582.26 ORY90341.1 - 3.6e-18 66.4 0.0 4.2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Pkinase PF00069.25 ORY90343.1 - 3.2e-65 220.1 0.0 3.7e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90343.1 - 2.2e-21 76.3 0.0 3.2e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY90343.1 - 0.00089 18.7 0.0 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY90343.1 - 0.0041 17.1 0.1 0.056 13.4 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family AAA_2 PF07724.14 ORY90344.1 - 7e-41 140.2 0.1 7e-41 140.2 0.1 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 ORY90344.1 - 6.2e-15 55.6 0.1 2.7e-07 31.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY90344.1 - 6.6e-15 55.3 0.3 3.7e-08 33.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY90344.1 - 4.4e-13 49.0 0.0 4.6e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY90344.1 - 1.4e-12 47.6 0.1 1.5e-05 25.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY90344.1 - 5.7e-12 44.7 0.0 1.6e-05 24.9 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat ClpB_D2-small PF10431.9 ORY90344.1 - 1.3e-10 41.2 0.1 1e-09 38.3 0.1 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY90344.1 - 3.5e-09 36.8 0.1 3.5e-08 33.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY90344.1 - 1.4e-07 32.0 0.0 3.3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY90344.1 - 8e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 ORY90344.1 - 0.00016 21.0 0.0 0.0005 19.4 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 ORY90344.1 - 0.00093 19.5 0.2 0.012 15.9 0.1 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY90344.1 - 0.0065 16.9 1.1 0.38 11.1 0.0 3.6 4 1 1 5 5 4 1 AAA ATPase domain ABC_tran PF00005.27 ORY90344.1 - 0.0067 16.9 0.4 0.024 15.1 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 ORY90344.1 - 0.0068 16.3 0.0 0.038 13.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 ORY90344.1 - 0.033 14.3 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.6 ORY90344.1 - 0.033 14.3 1.6 0.057 13.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 ORY90344.1 - 0.044 14.3 1.9 0.3 11.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 ORY90344.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.14 ORY90344.1 - 0.061 13.2 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 ORY90344.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase PHA_gran_rgn PF09650.10 ORY90344.1 - 0.1 12.9 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) AAA_23 PF13476.6 ORY90344.1 - 0.7 10.4 4.8 3.4 8.1 0.2 2.5 2 1 0 2 2 2 0 AAA domain Reprolysin_5 PF13688.6 ORY90345.1 - 4.3e-40 138.0 2.4 1e-39 136.7 2.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORY90345.1 - 2.4e-38 132.0 0.4 4.6e-38 131.1 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORY90345.1 - 1.6e-35 122.6 0.1 2.8e-35 121.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 ORY90345.1 - 1.1e-15 58.2 24.9 1.1e-15 58.2 24.9 4.3 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 ORY90345.1 - 6e-12 46.2 0.0 1.8e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 ORY90345.1 - 0.00037 20.5 5.1 0.00037 20.5 5.1 2.9 3 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 ORY90345.1 - 0.0064 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide TPR_1 PF00515.28 ORY90346.1 - 3.4e-61 200.7 34.6 8.7e-09 34.8 0.1 10.6 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY90346.1 - 1.5e-52 171.5 29.1 2.3e-06 27.3 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY90346.1 - 1.7e-39 130.7 25.9 5.6e-05 23.0 2.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORY90346.1 - 4.5e-33 113.6 12.9 3.5e-06 27.4 0.4 7.3 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORY90346.1 - 1.4e-30 103.4 11.7 7.7e-05 23.2 0.0 9.2 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 ORY90346.1 - 1.6e-29 102.3 12.4 9.8e-08 32.5 0.1 6.6 5 1 2 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY90346.1 - 2.1e-26 91.3 38.0 9.4e-07 28.4 0.6 9.6 3 2 6 9 9 9 7 TPR repeat TPR_17 PF13431.6 ORY90346.1 - 2.8e-26 90.0 22.7 9.3e-05 22.5 0.1 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_9 PF13371.6 ORY90346.1 - 3.6e-24 84.7 11.7 2.6e-06 27.5 0.8 6.0 3 2 4 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY90346.1 - 7.7e-23 80.6 22.0 7.2e-06 26.2 2.2 7.7 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 ORY90346.1 - 2.8e-21 74.7 19.6 0.041 14.5 1.2 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 ORY90346.1 - 2.7e-19 67.7 22.3 0.00021 21.1 0.2 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY90346.1 - 3.3e-14 52.9 15.1 4e-07 30.2 6.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORY90346.1 - 9.8e-11 41.4 13.3 0.25 10.5 0.2 5.8 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_21 PF09976.9 ORY90346.1 - 8e-08 32.2 5.2 0.0079 15.9 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat-like domain ChAPs PF09295.10 ORY90346.1 - 1.1e-05 24.6 3.2 0.16 11.0 0.1 3.1 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 ORY90346.1 - 2.6e-05 23.8 15.1 0.39 10.1 0.4 4.3 2 1 2 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_20 PF14561.6 ORY90346.1 - 0.00029 21.1 3.2 2.7 8.4 0.1 5.0 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY90346.1 - 0.00077 18.9 1.2 0.51 9.7 0.0 3.4 2 2 1 3 3 3 1 MalT-like TPR region BTAD PF03704.17 ORY90346.1 - 0.038 14.4 8.0 8.2 6.9 0.1 3.7 2 1 2 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 ORY90346.1 - 0.082 12.8 25.9 0.12 12.3 0.2 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat NARP1 PF12569.8 ORY90346.1 - 0.33 9.8 7.5 1.1 8.1 1.6 3.5 2 2 0 4 4 4 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 ORY90346.1 - 0.89 9.7 12.4 2.4 8.3 0.0 5.3 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.12 ORY90346.1 - 1.8 8.3 10.1 5.4 6.7 0.1 4.1 3 2 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.12 ORY90346.1 - 6.1 6.9 22.9 12 6.0 1.6 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat FYVE PF01363.21 ORY90347.1 - 1.4e-20 73.2 6.9 4.3e-20 71.6 6.9 1.9 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 ORY90347.1 - 5e-07 29.5 2.8 2.1 8.5 0.0 6.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat zf-RING_2 PF13639.6 ORY90347.1 - 1.8 9.0 9.3 5.1 7.5 9.3 1.9 1 0 0 1 1 1 0 Ring finger domain RibD_C PF01872.17 ORY90348.1 - 2.8e-39 135.0 0.2 3.5e-39 134.7 0.2 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Fungal_trans PF04082.18 ORY90349.1 - 0.00087 18.4 5.2 0.0015 17.7 0.8 3.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MMPL PF03176.15 ORY90349.1 - 0.34 9.8 1.3 0.53 9.2 1.3 1.2 1 0 0 1 1 1 0 MMPL family TFIIA PF03153.13 ORY90349.1 - 0.46 10.4 27.9 0.93 9.4 27.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OmpH PF03938.14 ORY90349.1 - 2.7 8.3 17.9 5.8 7.3 17.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MIP PF00230.20 ORY90350.1 - 6e-47 160.3 10.1 7.1e-47 160.0 10.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1743 PF08489.11 ORY90351.1 - 0.14 12.3 0.5 0.18 11.9 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1743) YbgS PF13985.6 ORY90351.1 - 3.8 7.8 6.9 7.6 6.9 0.5 2.2 1 1 0 2 2 2 0 YbgS-like protein ThiF PF00899.21 ORY90353.1 - 8.6e-111 369.1 0.0 1.3e-74 250.6 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 ORY90353.1 - 1.5e-96 323.2 0.1 3.9e-96 321.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 ORY90353.1 - 1.2e-37 128.5 3.2 1.6e-37 128.1 1.6 2.1 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 ORY90353.1 - 1e-33 115.3 0.1 2.5e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 ORY90353.1 - 3.7e-27 94.3 2.1 1e-26 92.9 2.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E2_bind PF08825.10 ORY90353.1 - 0.05 13.8 0.7 0.26 11.4 0.3 2.5 2 0 0 2 2 2 0 E2 binding domain DUF1724 PF08350.10 ORY90353.1 - 0.089 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) Exo_endo_phos PF03372.23 ORY90354.1 - 2.5e-08 33.7 0.0 4.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 ORY90354.1 - 0.00092 19.2 0.0 0.0035 17.3 0.0 1.9 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 ORY90354.1 - 0.0076 16.5 0.1 0.25 11.7 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY90354.1 - 0.096 13.6 0.3 5.1 8.1 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Spt5_N PF11942.8 ORY90354.1 - 1.7 9.6 7.7 2.6 9.1 3.5 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SAE2 PF08573.10 ORY90354.1 - 6.4 7.9 5.7 1.4 10.0 1.4 2.1 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus RhoGAP PF00620.27 ORY90355.1 - 4.3e-42 143.5 0.1 9.6e-42 142.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY90355.1 - 1.6e-15 57.5 0.0 3.5e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 ORY90355.1 - 4.7e-10 39.4 0.2 3.9e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 PX domain PH_11 PF15413.6 ORY90355.1 - 6.4e-06 26.5 0.0 2.1e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 ORY90355.1 - 0.0046 17.2 0.0 0.04 14.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Aminotran_1_2 PF00155.21 ORY90358.1 - 4.1e-54 184.1 0.0 5e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY90358.1 - 0.0076 15.2 0.2 0.054 12.5 0.2 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY90358.1 - 0.02 14.2 0.0 0.04 13.2 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORY90358.1 - 0.048 12.9 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ORY90358.1 - 0.089 11.3 0.1 0.19 10.2 0.1 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PIG-P PF08510.12 ORY90359.1 - 9.9e-41 138.5 7.9 1.3e-40 138.1 7.9 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 ORY90359.1 - 0.016 15.5 9.7 0.028 14.7 9.7 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Fip1 PF05182.13 ORY90361.1 - 2.6e-25 87.7 0.8 4.4e-25 86.9 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif RAP1 PF07218.11 ORY90361.1 - 9.6 4.3 9.7 13 3.9 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Oxidored_FMN PF00724.20 ORY90364.1 - 3.4e-99 332.4 0.0 3.9e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ELO PF01151.18 ORY90365.1 - 6.9e-66 222.3 7.7 8.6e-66 222.0 7.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MGAT2 PF05060.14 ORY90365.1 - 0.056 12.5 0.4 0.075 12.1 0.4 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) 4HBT PF03061.22 ORY90366.1 - 2e-08 34.5 0.0 3.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Zds_C PF08632.10 ORY90367.1 - 3.4e-26 90.7 3.7 5.8e-26 90.0 3.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term BTB_2 PF02214.22 ORY90368.1 - 1.6e-20 73.3 0.7 3.8e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Pentapeptide PF00805.22 ORY90368.1 - 0.0056 16.3 0.0 3.3 7.5 0.0 2.7 3 0 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 ORY90368.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 ORY90368.1 - 0.059 13.5 0.4 0.23 11.7 0.4 2.0 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) tRNA-synt_1 PF00133.22 ORY90370.1 - 9.5e-174 579.0 0.1 1.3e-173 578.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY90370.1 - 2.3e-30 105.5 1.5 4.8e-30 104.5 1.5 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY90370.1 - 7.8e-21 74.3 0.3 2.5e-13 49.6 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORY90370.1 - 6.5e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 ORY90370.1 - 8.3e-05 22.4 3.7 0.00017 21.4 3.7 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 ORY90370.1 - 0.058 12.7 0.1 5.9 6.1 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Glyco_trans_4_3 PF12000.8 ORY90371.1 - 0.052 13.2 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 4 group CLP1_P PF16575.5 ORY90372.1 - 1.4e-30 106.5 0.0 3e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 ORY90372.1 - 0.0024 18.3 1.5 0.0051 17.2 0.0 2.3 2 1 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 ATPase_2 PF01637.18 ORY90372.1 - 0.0025 17.8 0.0 0.008 16.1 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY90372.1 - 0.0049 17.1 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY90372.1 - 0.0055 17.2 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY90372.1 - 0.0084 16.3 0.1 0.043 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY90372.1 - 0.015 15.6 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 ORY90372.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Auto_anti-p27 PF06677.12 ORY90373.1 - 2.2e-26 91.7 4.3 2.6e-12 46.7 0.6 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CxC6 PF18721.1 ORY90373.1 - 0.038 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases CCDC53 PF10152.9 ORY90373.1 - 4.3 7.7 7.9 9.6 6.6 1.9 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PRCC PF10253.9 ORY90373.1 - 6.3 7.5 10.9 5.5 7.7 1.5 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting p450 PF00067.22 ORY90374.1 - 4.1e-84 283.0 0.0 3.9e-83 279.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 NAPRTase PF04095.16 ORY90375.1 - 1.7e-65 221.0 0.4 2.5e-65 220.5 0.4 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 ORY90375.1 - 1.6e-35 122.3 1.8 2.9e-35 121.4 1.8 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Egg_lysin PF01303.17 ORY90375.1 - 0.033 14.4 0.4 0.19 12.0 0.3 2.2 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) RNase_T PF00929.24 ORY90376.1 - 2.1e-16 60.9 0.0 6.1e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 Exonuclease Cwf_Cwc_15 PF04889.12 ORY90376.1 - 0.00037 20.3 17.0 0.00046 20.0 17.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF755 PF05501.11 ORY90376.1 - 0.0012 19.1 18.0 0.002 18.4 18.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) FAM60A PF15396.6 ORY90376.1 - 0.02 14.9 12.1 0.028 14.4 12.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DBINO PF13892.6 ORY90376.1 - 0.041 14.2 15.0 0.07 13.5 15.0 1.4 1 0 0 1 1 1 0 DNA-binding domain ATP-synt_E PF05680.12 ORY90376.1 - 0.62 10.4 9.4 1.3 9.4 9.4 1.5 1 0 0 1 1 1 0 ATP synthase E chain DDHD PF02862.17 ORY90376.1 - 1.3 9.1 6.5 1.6 8.8 6.5 1.2 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.10 ORY90376.1 - 3 8.2 17.7 3.9 7.8 17.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CSRNP_N PF16019.5 ORY90376.1 - 3.7 7.4 11.9 5.2 6.9 11.9 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Spore_coat_CotO PF14153.6 ORY90376.1 - 3.9 7.3 17.0 5.7 6.8 17.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CENP-Q PF13094.6 ORY90376.1 - 7.6 6.7 18.6 15 5.8 18.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Enolase_C PF00113.22 ORY90377.1 - 1e-157 523.9 0.2 1.3e-157 523.6 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORY90377.1 - 3.4e-57 192.3 0.2 7.4e-57 191.2 0.1 1.7 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORY90377.1 - 5.8e-06 26.0 0.0 1.5e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORY90377.1 - 0.011 15.0 0.3 0.026 13.7 0.1 1.7 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Aldo_ket_red PF00248.21 ORY90378.1 - 7.9e-24 84.4 0.0 1.7e-23 83.3 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family ERCC3_RAD25_C PF16203.5 ORY90379.1 - 2.7e-63 213.5 1.9 7.5e-33 113.8 0.3 2.6 1 1 1 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 ORY90379.1 - 3.4e-19 69.5 0.0 7.4e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY90379.1 - 6.3e-09 35.0 0.0 1.3e-07 30.6 0.0 2.2 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY90379.1 - 4e-08 33.6 1.3 8.2e-08 32.6 0.3 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY90379.1 - 4.5e-08 33.0 0.0 4.5e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY90379.1 - 0.00018 21.3 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 ORY90379.1 - 0.0043 16.0 0.0 0.0066 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Trimer_CC PF08954.11 ORY90379.1 - 0.072 12.7 0.7 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Trimerisation motif SAM_2 PF07647.17 ORY90380.1 - 7.5e-13 48.4 0.2 1.9e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 ORY90380.1 - 1.6e-12 47.9 0.0 2.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 ORY90380.1 - 6.5e-11 42.5 1.0 1.5e-10 41.4 0.4 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DivIC PF04977.15 ORY90380.1 - 0.022 14.5 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator SAM_4 PF18017.1 ORY90380.1 - 0.047 13.7 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MAP65_ASE1 PF03999.12 ORY90380.1 - 3.5 6.2 8.3 6 5.4 8.3 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) CBP_BcsO PF17037.5 ORY90380.1 - 8 6.6 12.0 12 6.0 9.9 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Mucin PF01456.17 ORY90380.1 - 9.4 6.2 20.0 8.3 6.4 15.8 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein ABC_tran PF00005.27 ORY90381.1 - 1.9e-48 164.5 0.0 1.4e-24 87.2 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY90381.1 - 7.6e-16 58.8 0.8 0.00018 21.4 0.2 4.4 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY90381.1 - 1.9e-15 56.9 0.1 1.5e-05 24.6 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY90381.1 - 3.6e-08 33.8 0.0 0.038 14.3 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 ORY90381.1 - 9.9e-08 32.5 0.0 0.0056 17.1 0.0 3.9 3 1 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY90381.1 - 1.9e-07 30.7 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY90381.1 - 3.4e-07 30.3 0.0 0.0068 16.3 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_28 PF13521.6 ORY90381.1 - 8.7e-07 29.3 0.0 0.02 15.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORY90381.1 - 2.3e-06 27.7 0.0 0.023 14.8 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY90381.1 - 3.4e-06 27.6 0.0 0.24 12.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY90381.1 - 3.6e-06 27.5 0.7 0.067 13.6 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain MeaB PF03308.16 ORY90381.1 - 6.7e-06 25.3 0.1 0.017 14.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 ORY90381.1 - 1.3e-05 25.4 0.0 0.36 11.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 ORY90381.1 - 2e-05 24.5 1.5 0.19 11.4 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain Chromo PF00385.24 ORY90381.1 - 2.1e-05 24.3 1.4 5.3e-05 23.0 0.3 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RNA_helicase PF00910.22 ORY90381.1 - 2.1e-05 24.8 0.0 0.096 13.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 ORY90381.1 - 8e-05 22.4 2.7 1.1 8.9 0.1 4.3 4 1 0 5 5 4 1 AAA domain AAA_14 PF13173.6 ORY90381.1 - 8.6e-05 22.6 0.0 0.12 12.4 0.0 3.5 2 1 1 3 3 3 1 AAA domain Rad17 PF03215.15 ORY90381.1 - 9.8e-05 22.4 0.5 0.16 11.9 0.0 2.7 3 0 0 3 3 2 2 Rad17 P-loop domain NACHT PF05729.12 ORY90381.1 - 0.00015 21.8 0.1 0.15 12.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain PduV-EutP PF10662.9 ORY90381.1 - 0.00036 20.3 0.0 0.57 9.9 0.0 2.7 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 ORY90381.1 - 0.00047 19.4 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_27 PF13514.6 ORY90381.1 - 0.0017 18.0 0.0 1.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY90381.1 - 0.0027 17.3 0.7 1.5 8.3 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 ORY90381.1 - 0.0036 17.0 0.1 1.1 8.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 ORY90381.1 - 0.0037 17.8 19.7 0.006 17.1 0.0 4.0 4 1 0 4 4 3 2 AAA domain CLP1_P PF16575.5 ORY90381.1 - 0.0043 16.9 0.0 0.64 9.8 0.0 3.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SbcCD_C PF13558.6 ORY90381.1 - 0.0048 17.1 0.1 0.3 11.4 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 ORY90381.1 - 0.0049 16.1 0.0 0.9 8.7 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain HEAT PF02985.22 ORY90381.1 - 0.0051 17.0 1.1 2.1 8.8 0.1 4.5 4 0 0 4 4 3 1 HEAT repeat HEAT_2 PF13646.6 ORY90381.1 - 0.0061 16.9 5.3 0.16 12.3 0.0 3.8 3 1 1 4 4 4 1 HEAT repeats IstB_IS21 PF01695.17 ORY90381.1 - 0.007 16.1 0.0 7.4 6.3 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 ORY90381.1 - 0.013 15.4 0.0 4.3 7.2 0.0 3.0 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 ORY90381.1 - 0.014 15.2 0.0 4.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Adeno_IVa2 PF02456.15 ORY90381.1 - 0.024 13.4 0.0 1.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 ORY90381.1 - 0.029 14.4 0.1 13 5.8 0.0 3.4 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 ORY90381.1 - 0.029 14.4 2.5 0.21 11.6 0.0 3.0 3 0 0 3 3 2 0 Dynamin family TsaE PF02367.17 ORY90381.1 - 0.032 14.2 0.0 7.6 6.6 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 ORY90381.1 - 0.032 14.3 3.5 1.2 9.1 0.1 3.7 4 0 0 4 4 3 0 Helicase HerA, central domain ATPase_2 PF01637.18 ORY90381.1 - 0.037 14.0 8.6 0.19 11.6 0.0 3.8 4 1 0 4 4 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 ORY90381.1 - 0.054 12.8 1.7 4.2 6.6 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin AAA_13 PF13166.6 ORY90381.1 - 0.07 11.8 4.6 5.9 5.4 0.1 3.7 4 0 0 4 4 3 0 AAA domain PRK PF00485.18 ORY90381.1 - 0.09 12.5 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 ORY90381.1 - 0.11 12.7 0.0 20 5.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 ORY90381.1 - 0.12 12.1 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF4500 PF14937.6 ORY90381.1 - 0.16 12.0 0.2 0.53 10.3 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4500) ERG2_Sigma1R PF04622.12 ORY90383.1 - 7.8e-85 283.5 0.1 9.3e-85 283.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PEMT PF04191.13 ORY90384.1 - 9.8e-34 115.9 3.5 1.8e-33 115.1 3.5 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase YrhK PF14145.6 ORY90384.1 - 0.32 10.9 6.2 0.64 9.9 0.4 2.9 3 0 0 3 3 3 0 YrhK-like protein TAF8_C PF10406.9 ORY90385.1 - 2.1e-17 63.4 1.6 2.1e-17 63.4 1.6 2.3 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 ORY90385.1 - 3.2e-14 52.7 0.0 5.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 ORY90385.1 - 0.021 14.9 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1931 PF09123.11 ORY90385.1 - 0.064 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) DUF1242 PF06842.12 ORY90386.1 - 3.5e-18 65.1 0.4 4.6e-18 64.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) GRAM PF02893.20 ORY90387.1 - 7.5e-24 83.8 0.0 1.6e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain SecD-TM1 PF13721.6 ORY90387.1 - 0.23 11.9 7.2 0.041 14.4 2.2 2.3 2 1 1 3 3 3 0 SecD export protein N-terminal TM region RskA PF10099.9 ORY90387.1 - 5.3 7.3 6.8 1.8 8.8 3.0 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA ACBP PF00887.19 ORY90388.1 - 2.4e-17 62.9 0.9 2.8e-17 62.7 0.9 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Mg_trans_NIPA PF05653.14 ORY90389.1 - 0.18 10.9 1.2 0.33 10.0 1.2 1.3 1 0 0 1 1 1 0 Magnesium transporter NIPA Baculo_11_kDa PF06143.11 ORY90389.1 - 0.19 11.3 2.3 0.57 9.8 2.3 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Spc7 PF08317.11 ORY90391.1 - 4.6e-34 117.7 8.0 7.5e-34 117.0 8.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 ORY90391.1 - 0.31 11.3 6.3 5 7.4 2.9 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 ORY90391.1 - 0.43 10.4 6.3 0.95 9.3 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Med9 PF07544.13 ORY90391.1 - 0.47 10.6 7.7 0.76 9.9 0.4 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 ORY90391.1 - 4.2 7.9 19.0 5.7 7.5 6.8 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PPR_2 PF13041.6 ORY90392.1 - 3.2e-33 113.7 0.0 3.9e-10 39.8 0.0 6.9 6 1 1 7 7 7 4 PPR repeat family PPR_1 PF12854.7 ORY90392.1 - 2.6e-16 59.0 1.8 0.00042 20.0 0.0 5.2 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.6 ORY90392.1 - 5.1e-14 52.1 6.7 0.00037 20.5 0.0 7.0 6 2 2 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.20 ORY90392.1 - 3.7e-13 48.8 3.3 0.0001 22.3 0.0 8.6 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 ORY90392.1 - 4.8e-05 22.8 0.0 0.082 12.3 0.0 3.1 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP EH_Signature PF15611.6 ORY90392.1 - 0.072 12.5 0.6 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 EH_Signature domain FAD_binding_3 PF01494.19 ORY90395.1 - 1.5e-26 93.5 1.7 1.8e-11 43.9 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 ORY90395.1 - 7.9e-06 25.3 0.0 0.069 12.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY90395.1 - 0.00019 21.9 0.0 0.8 10.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY90395.1 - 0.0002 21.5 0.0 0.00055 20.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY90395.1 - 0.0002 20.7 0.1 0.16 11.2 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY90395.1 - 0.0038 16.9 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY90395.1 - 0.0051 15.9 0.1 0.76 8.8 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 ORY90395.1 - 0.014 14.2 0.0 2.2 6.9 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 ORY90395.1 - 0.05 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain ImpE PF07024.13 ORY90395.1 - 0.06 13.4 0.5 0.37 10.9 0.0 2.3 3 0 0 3 3 3 0 ImpE protein Acetyltransf_1 PF00583.25 ORY90396.1 - 1.4e-06 28.6 0.0 2.4e-06 27.8 0.0 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY90396.1 - 0.00025 21.4 0.0 0.00039 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY90396.1 - 0.0064 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY90396.1 - 0.047 14.4 0.0 0.058 14.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY90396.1 - 0.079 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hydrolase_4 PF12146.8 ORY90397.1 - 1.2e-13 51.0 0.1 1.5e-09 37.5 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY90397.1 - 6.9e-10 39.0 0.1 2.5e-07 30.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY90397.1 - 3.6e-06 26.6 0.0 1.8e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 ORY90397.1 - 0.00016 20.5 0.1 0.43 9.2 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 ORY90397.1 - 0.001 19.7 0.0 0.0014 19.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 ORY90397.1 - 0.0016 17.5 0.1 0.0022 17.0 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.18 ORY90397.1 - 0.003 17.2 0.0 0.053 13.1 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 ORY90397.1 - 0.029 14.3 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UME PF08064.13 ORY90398.1 - 0.12 12.2 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 UME (NUC010) domain WD40 PF00400.32 ORY90399.1 - 3.3e-31 106.8 14.5 5.9e-07 30.1 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY90399.1 - 4.3e-12 46.2 0.6 0.0023 18.2 0.0 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 ORY90399.1 - 0.0069 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 ORY90399.1 - 0.039 13.5 0.0 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.8 ORY90399.1 - 0.081 11.6 0.1 0.21 10.2 0.0 1.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 CCDC53 PF10152.9 ORY90401.1 - 0.01 16.2 13.5 0.01 16.2 13.5 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TERB2 PF15101.6 ORY90401.1 - 3.2 7.7 31.1 0.033 14.2 21.2 2.1 1 1 1 2 2 2 0 Telomere-associated protein TERB2 Suf PF05843.14 ORY90401.1 - 3.6 7.5 20.5 5.1 7.0 20.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KIP1 PF07765.12 ORY90401.1 - 7.2 6.8 11.1 4.7 7.4 1.2 2.8 2 1 0 2 2 2 0 KIP1-like protein V_ATPase_I PF01496.19 ORY90401.1 - 9.7 4.0 27.4 11 3.8 26.7 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 ORY90402.1 - 9.6e-18 64.3 0.0 1.2e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 ORY90402.1 - 0.031 14.2 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Apg6 BARA domain DNA_pol_phi PF04931.13 ORY90403.1 - 9.5 4.2 5.9 12 3.8 5.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sel1 PF08238.12 ORY90404.1 - 9.3e-41 137.4 26.9 2.4e-08 34.4 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat DnaJ PF00226.31 ORY90406.1 - 2.9e-20 72.2 1.9 6e-20 71.1 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Zn_Tnp_IS91 PF14319.6 ORY90408.1 - 0.0015 18.5 1.7 0.057 13.5 0.5 2.1 2 0 0 2 2 2 1 Transposase zinc-binding domain NapB PF03892.14 ORY90408.1 - 0.0088 16.1 0.2 0.011 15.8 0.2 1.2 1 0 0 1 1 1 1 Nitrate reductase cytochrome c-type subunit (NapB) Ribosomal_L37ae PF01780.19 ORY90408.1 - 0.043 13.9 0.2 0.083 13.0 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family Zn-ribbon_8 PF09723.10 ORY90408.1 - 1.7 8.8 8.2 0.97 9.6 0.4 2.7 2 1 2 4 4 4 0 Zinc ribbon domain DZR PF12773.7 ORY90408.1 - 1.8 8.7 6.9 0.22 11.6 2.0 2.0 3 0 0 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.6 ORY90408.1 - 9 6.3 9.1 7.9 6.5 5.8 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 SKI PF01202.22 ORY90414.1 - 5.6e-08 33.1 0.0 8.4e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 ORY90414.1 - 1.3e-05 25.8 0.0 2.7e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY90414.1 - 0.00026 21.2 0.0 0.00039 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORY90414.1 - 0.00065 20.1 0.0 0.0012 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY90414.1 - 0.018 15.4 0.0 0.031 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY90414.1 - 0.038 14.3 0.2 0.46 10.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY90414.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain EzrA PF06160.12 ORY90415.1 - 0.00097 17.4 5.4 0.0014 16.9 5.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Elf1 PF05129.13 ORY90415.1 - 0.015 15.4 0.4 0.05 13.6 0.4 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TPR_MLP1_2 PF07926.12 ORY90415.1 - 0.027 14.5 13.7 0.043 13.9 3.0 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 ORY90415.1 - 0.08 13.0 4.8 0.54 10.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 ORY90415.1 - 0.086 13.1 18.4 0.33 11.2 10.0 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.6 ORY90415.1 - 0.1 13.1 0.2 0.1 13.1 0.2 3.2 1 1 0 3 3 3 0 Snapin/Pallidin TMF_TATA_bd PF12325.8 ORY90415.1 - 0.11 12.8 10.3 1.6 8.9 1.9 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ax_dynein_light PF10211.9 ORY90415.1 - 0.11 12.5 8.2 0.96 9.4 1.3 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain DUF948 PF06103.11 ORY90415.1 - 0.13 12.5 1.9 0.2 12.0 0.6 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cytochrom_c3_2 PF14537.6 ORY90415.1 - 0.14 12.6 1.0 0.35 11.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c3 Vps53_N PF04100.12 ORY90415.1 - 0.15 11.0 1.9 5.2 5.9 0.9 2.1 1 1 1 2 2 2 0 Vps53-like, N-terminal DUF5082 PF16888.5 ORY90415.1 - 0.18 12.1 6.3 0.6 10.4 6.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Tropomyosin_1 PF12718.7 ORY90415.1 - 0.26 11.5 8.7 0.69 10.1 0.9 2.5 2 0 0 2 2 2 0 Tropomyosin like ZapB PF06005.12 ORY90415.1 - 0.37 11.3 14.7 0.98 9.9 4.7 3.2 2 1 1 3 3 3 0 Cell division protein ZapB Filament PF00038.21 ORY90415.1 - 0.4 10.2 13.9 1.4 8.4 14.0 1.7 1 1 0 1 1 1 0 Intermediate filament protein DUF4201 PF13870.6 ORY90415.1 - 0.52 10.0 9.8 0.6 9.8 7.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF812 PF05667.11 ORY90415.1 - 0.6 8.9 9.3 2.1 7.1 9.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.8 ORY90415.1 - 0.61 10.1 6.5 5.2 7.2 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IFT57 PF10498.9 ORY90415.1 - 0.72 8.8 5.9 1.1 8.1 5.9 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 ORY90415.1 - 0.75 10.0 7.0 2.8 8.1 4.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY90415.1 - 0.86 10.1 2.9 3.4 8.2 0.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cep57_CLD_2 PF14197.6 ORY90415.1 - 0.9 9.7 11.1 0.28 11.3 1.1 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 ORY90415.1 - 1.2 9.0 19.8 1.3 8.9 3.9 3.4 1 1 2 3 3 3 0 Septum formation initiator SHE3 PF17078.5 ORY90415.1 - 1.2 8.8 8.1 9 5.9 8.1 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 ORY90415.1 - 1.2 8.4 12.1 2.7 7.3 12.1 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 ORY90415.1 - 1.8 9.1 21.4 1.1 9.8 4.0 2.7 2 1 1 3 3 2 0 Apg6 coiled-coil region DUF4763 PF15960.5 ORY90415.1 - 1.9 7.7 10.1 0.29 10.4 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF4140 PF13600.6 ORY90415.1 - 2 8.9 16.6 3.4 8.2 0.9 3.3 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3450 PF11932.8 ORY90415.1 - 2.7 7.3 18.2 0.17 11.1 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) COG2 PF06148.11 ORY90415.1 - 3.2 7.9 6.3 6.5 6.9 1.7 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BRE1 PF08647.11 ORY90415.1 - 3.3 7.8 11.4 0.34 11.0 1.9 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 ORY90415.1 - 3.6 8.3 16.6 2.7 8.7 4.5 3.5 3 1 0 3 3 3 0 SlyX CENP-Q PF13094.6 ORY90415.1 - 5 7.3 14.1 19 5.4 14.0 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 ORY90415.1 - 5.5 6.3 19.1 8.7 5.6 11.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 ORY90415.1 - 6.3 5.6 11.7 19 4.0 11.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 ORY90415.1 - 7.6 7.3 10.4 3.5 8.4 1.0 2.4 1 1 0 2 2 2 0 Occludin homology domain ADIP PF11559.8 ORY90415.1 - 8.4 6.5 14.1 0.5 10.4 3.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 ORY90415.1 - 8.4 6.6 14.5 26 5.0 3.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 V-ATPase_C PF03223.15 ORY90416.1 - 6.9e-115 384.4 8.2 7.8e-115 384.2 8.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 ORY90416.1 - 0.0022 18.6 0.1 0.0069 17.0 0.1 1.9 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Fib_alpha PF08702.10 ORY90416.1 - 0.017 15.3 5.9 0.034 14.3 5.9 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY90416.1 - 0.38 11.3 3.9 5.7 7.5 0.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 ORY90417.1 - 2.9e-47 160.6 0.8 1.1e-22 81.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY90417.1 - 7.2e-23 80.4 2.4 7.2e-23 80.4 2.4 3.7 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 ORY90417.1 - 8.6e-14 52.0 0.8 0.01 15.7 0.3 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY90417.1 - 3.4e-11 43.0 5.4 0.004 16.6 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY90417.1 - 6e-08 33.2 0.3 0.021 15.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY90417.1 - 1.3e-07 31.7 0.0 0.0024 17.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY90417.1 - 2.2e-07 31.6 19.9 0.094 13.2 0.0 5.1 5 0 0 5 5 5 3 AAA domain AAA_22 PF13401.6 ORY90417.1 - 7.9e-07 29.4 0.3 0.045 14.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORY90417.1 - 1.6e-06 28.2 0.0 0.1 12.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY90417.1 - 1.6e-06 27.8 0.0 0.035 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 ORY90417.1 - 4.5e-06 26.7 0.1 0.14 12.1 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.6 ORY90417.1 - 1.4e-05 25.6 0.3 0.37 11.3 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_28 PF13521.6 ORY90417.1 - 1.4e-05 25.4 0.3 0.24 11.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 ORY90417.1 - 1.6e-05 25.3 0.1 0.74 10.3 0.0 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY90417.1 - 0.00011 22.6 0.0 0.15 12.5 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 ORY90417.1 - 0.00014 22.0 1.9 0.84 9.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_27 PF13514.6 ORY90417.1 - 0.0003 20.5 0.8 0.32 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 ORY90417.1 - 0.00037 20.3 0.0 0.97 9.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY90417.1 - 0.00041 20.1 0.1 0.087 12.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY90417.1 - 0.0025 17.8 2.3 3 7.9 0.0 3.6 4 0 0 4 4 3 2 AAA domain MeaB PF03308.16 ORY90417.1 - 0.0029 16.6 0.1 2.8 6.9 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 ORY90417.1 - 0.0038 17.3 7.5 0.14 12.2 0.4 3.5 3 1 0 4 4 3 1 Dynamin family DUF87 PF01935.17 ORY90417.1 - 0.0041 17.3 16.2 0.16 12.0 0.0 4.8 4 1 2 6 6 5 2 Helicase HerA, central domain NB-ARC PF00931.22 ORY90417.1 - 0.0079 15.4 0.0 0.88 8.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 ORY90417.1 - 0.0082 15.7 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 ORY90417.1 - 0.0096 15.2 2.7 0.11 11.8 0.0 3.0 3 1 1 4 4 4 1 KAP family P-loop domain NTPase_1 PF03266.15 ORY90417.1 - 0.013 15.4 0.1 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 ORY90417.1 - 0.019 14.9 0.1 30 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 ORY90417.1 - 0.021 15.0 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 ORY90417.1 - 0.029 14.1 0.8 0.31 10.7 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase AAA_7 PF12775.7 ORY90417.1 - 0.032 13.8 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 ORY90417.1 - 0.032 14.5 1.7 0.36 11.1 0.2 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ORY90417.1 - 0.034 13.9 19.8 0.43 10.2 0.1 5.0 4 1 0 6 6 6 0 AAA ATPase domain IstB_IS21 PF01695.17 ORY90417.1 - 0.046 13.5 0.0 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 ORY90417.1 - 0.05 13.5 0.1 0.33 10.8 0.0 2.3 3 0 0 3 3 2 0 Rad17 P-loop domain cobW PF02492.19 ORY90417.1 - 0.054 13.1 0.0 9.9 5.7 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2205 PF10224.9 ORY90417.1 - 0.057 13.4 4.7 0.26 11.3 4.7 2.2 1 0 0 1 1 1 0 Short coiled-coil protein Septin PF00735.18 ORY90417.1 - 0.093 12.0 0.8 18 4.5 0.0 3.0 3 0 0 3 3 3 0 Septin Ploopntkinase3 PF18751.1 ORY90417.1 - 0.11 12.4 0.2 6.9 6.5 0.0 3.1 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 ORY90417.1 - 0.15 11.9 1.1 5.4 6.7 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein DUF5320 PF17253.2 ORY90417.1 - 3.6 8.7 11.2 0.18 12.9 1.9 3.1 3 0 0 3 3 2 0 Family of unknown function (DUF5320) Lipase_GDSL PF00657.22 ORY90421.1 - 2.2e-12 47.3 0.0 5.8e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY90421.1 - 7.7e-08 32.9 0.2 0.00088 19.7 0.0 2.4 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 ORY90422.1 - 0.031 14.7 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY90422.1 - 0.052 13.5 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Fer2_4 PF13510.6 ORY90426.1 - 0.039 14.0 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Lipase_GDSL_2 PF13472.6 ORY90426.1 - 0.15 12.5 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.7 ORY90431.1 - 6.2e-10 38.8 1.2 1.5e-09 37.5 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY90431.1 - 0.00072 19.4 0.7 0.0021 17.9 0.7 1.8 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 ORY90431.1 - 0.0016 18.2 0.1 0.012 15.3 0.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat TPR_7 PF13176.6 ORY90431.1 - 0.041 13.9 2.6 0.14 12.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY90431.1 - 0.056 13.6 3.5 0.1 12.7 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.7 ORY90431.1 - 0.078 13.4 10.3 0.46 11.0 0.3 5.2 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) TPR_14 PF13428.6 ORY90431.1 - 0.7 10.9 3.9 0.96 10.4 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Lipase_GDSL PF00657.22 ORY90432.1 - 1.2e-11 44.9 0.0 3.1e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY90432.1 - 3.6e-07 30.7 0.0 0.00012 22.6 0.0 2.5 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.7 ORY90434.1 - 4.5e-06 26.5 2.2 1e-05 25.3 2.2 1.7 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.6 ORY90434.1 - 0.017 15.9 0.5 5 8.2 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY90434.1 - 0.057 14.1 0.3 0.17 12.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY90434.1 - 0.12 12.5 0.0 0.45 10.8 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 ORY90434.1 - 0.21 11.7 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) W2 PF02020.18 ORY90435.1 - 2.3e-21 75.7 2.9 6.8e-21 74.2 2.9 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 ORY90435.1 - 3.5e-11 42.3 11.3 0.00011 21.8 0.3 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 ORY90435.1 - 3e-06 27.0 0.0 5.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 ORY90435.1 - 0.0002 21.0 9.2 0.00074 19.2 2.7 3.3 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORY90435.1 - 0.00044 18.5 3.2 0.00075 17.8 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 ORY90435.1 - 0.076 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain NDUF_B4 PF07225.12 ORY90435.1 - 0.081 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Fucokinase PF07959.12 ORY90435.1 - 0.13 11.2 0.1 0.25 10.3 0.1 1.4 1 0 0 1 1 1 0 L-fucokinase CTP_transf_3 PF02348.19 ORY90435.1 - 0.51 10.2 2.4 0.65 9.9 0.4 2.3 2 1 0 2 2 2 0 Cytidylyltransferase F-box-like PF12937.7 ORY90436.1 - 1.5e-06 28.0 1.8 3.9e-06 26.7 1.8 1.8 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 ORY90436.1 - 0.016 15.3 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY90436.1 - 0.027 14.3 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box PF00646.33 ORY90436.1 - 0.094 12.6 0.1 0.29 11.1 0.1 1.9 1 0 0 1 1 1 0 F-box domain TPR_11 PF13414.6 ORY90436.1 - 0.19 11.4 0.1 0.56 9.9 0.1 1.8 1 1 0 1 1 1 0 TPR repeat TFIIS_C PF01096.18 ORY90437.1 - 4.5e-18 64.8 7.6 2.7e-17 62.3 1.5 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORY90437.1 - 1.3e-06 28.1 12.3 0.00091 19.0 0.3 3.1 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DUF523 PF04463.12 ORY90437.1 - 1.6e-05 25.0 0.6 2e-05 24.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) DZR PF12773.7 ORY90437.1 - 0.00011 22.1 8.6 0.043 13.8 0.1 2.9 2 1 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 ORY90437.1 - 0.0019 18.2 6.2 0.016 15.2 0.5 2.9 2 1 0 2 2 2 1 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.17 ORY90437.1 - 0.0024 17.7 4.4 0.026 14.4 1.0 2.3 2 1 0 2 2 2 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ORY90437.1 - 0.0038 16.7 11.5 0.013 15.0 1.3 3.1 2 2 1 3 3 3 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 ORY90437.1 - 0.0098 15.8 6.6 0.21 11.5 0.1 2.8 2 1 0 2 2 2 1 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.10 ORY90437.1 - 0.013 15.2 13.5 5.8 6.7 0.2 4.3 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 ORY90437.1 - 0.028 13.8 18.6 0.33 10.4 1.1 3.6 3 1 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.12 ORY90437.1 - 0.03 14.3 10.8 0.083 12.9 2.1 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 ORY90437.1 - 0.031 14.8 10.9 1.5 9.4 1.0 3.1 2 2 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF35_N PF12172.8 ORY90437.1 - 0.042 13.7 2.8 19 5.3 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C4_Topoisom PF01396.19 ORY90437.1 - 0.059 13.2 10.7 4.4 7.2 0.1 3.0 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Prok-RING_1 PF14446.6 ORY90437.1 - 0.06 13.3 9.6 0.2 11.6 1.6 3.5 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 Nudix_N_2 PF14803.6 ORY90437.1 - 0.061 13.3 8.9 4.6 7.3 0.1 3.8 3 1 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 ORY90437.1 - 0.065 13.0 18.4 1.3 8.9 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Rpr2 PF04032.16 ORY90437.1 - 0.074 13.3 6.8 0.085 13.2 2.6 2.3 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Baculo_LEF5_C PF11792.8 ORY90437.1 - 0.076 12.7 0.1 0.076 12.7 0.1 2.6 3 0 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain tRNA-synt_1f PF01921.18 ORY90437.1 - 0.084 11.8 2.4 0.064 12.2 1.6 1.3 1 1 0 1 1 1 0 tRNA synthetases class I (K) NOB1_Zn_bind PF08772.11 ORY90437.1 - 0.1 12.8 9.1 12 6.2 0.0 3.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ISL3 PF14690.6 ORY90437.1 - 0.1 13.3 6.4 4.9 7.9 0.1 3.4 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Auto_anti-p27 PF06677.12 ORY90437.1 - 0.12 12.6 12.3 2.9 8.1 4.6 3.0 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mu-like_Com PF10122.9 ORY90437.1 - 0.12 11.9 3.6 5.7 6.5 0.0 2.7 3 0 0 3 3 2 0 Mu-like prophage protein Com Zn_Tnp_IS91 PF14319.6 ORY90437.1 - 0.12 12.4 8.3 0.33 11.0 2.8 2.5 1 1 1 2 2 2 0 Transposase zinc-binding domain Rubredoxin PF00301.20 ORY90437.1 - 0.13 12.3 11.9 4.1 7.5 1.1 4.0 4 0 0 4 4 4 0 Rubredoxin C1_1 PF00130.22 ORY90437.1 - 0.13 12.2 3.0 6.8 6.7 0.1 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_4 PF13717.6 ORY90437.1 - 0.15 12.0 9.9 16 5.5 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-IS66 PF13005.7 ORY90437.1 - 0.16 12.4 8.8 2.7 8.5 0.1 3.6 4 0 0 4 4 3 0 zinc-finger binding domain of transposase IS66 GFA PF04828.14 ORY90437.1 - 0.18 12.1 9.8 1.7 9.1 1.4 3.1 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-H2C2_2 PF13465.6 ORY90437.1 - 0.18 12.3 9.4 0.24 11.9 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain DpnI PF06044.12 ORY90437.1 - 0.2 11.3 4.9 0.67 9.6 0.7 2.2 1 1 1 2 2 2 0 Dam-replacing family zinc_ribbon_9 PF14369.6 ORY90437.1 - 0.22 11.8 7.4 15 6.0 0.1 3.6 4 0 0 4 4 3 0 zinc-ribbon zf-RING_7 PF02591.15 ORY90437.1 - 0.26 11.5 0.1 0.26 11.5 0.1 3.8 4 1 0 4 4 4 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 ORY90437.1 - 0.34 11.1 14.4 3.9 7.7 0.2 3.9 3 1 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 ORY90437.1 - 0.34 10.7 11.4 6.7 6.5 0.1 3.9 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DNA_RNApol_7kD PF03604.13 ORY90437.1 - 0.35 10.6 8.6 11 5.8 0.6 3.9 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.6 ORY90437.1 - 0.54 10.4 11.8 2.4 8.3 0.3 3.4 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 LisH_2 PF16045.5 ORY90437.1 - 0.61 9.2 4.1 1.4 8.0 0.4 2.8 3 0 0 3 3 3 0 LisH MqsA_antitoxin PF15731.5 ORY90437.1 - 0.7 10.0 4.9 3.5 7.7 0.6 2.6 2 1 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-TFIIB PF13453.6 ORY90437.1 - 0.88 8.9 8.9 0.21 10.9 1.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DNA_ligase_ZBD PF03119.16 ORY90437.1 - 1.1 9.4 6.6 2.6 8.1 0.2 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF3268 PF11672.8 ORY90437.1 - 1.1 9.5 7.2 0.27 11.6 2.0 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain PHD PF00628.29 ORY90437.1 - 1.2 9.1 9.0 0.41 10.6 0.6 2.8 2 2 0 2 2 2 0 PHD-finger Ribosomal_S27e PF01667.17 ORY90437.1 - 1.2 8.9 8.0 4.3 7.1 0.2 3.1 2 1 0 2 2 2 0 Ribosomal protein S27 DUF3797 PF12677.7 ORY90437.1 - 1.3 9.0 8.5 20 5.2 5.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) ArfGap PF01412.18 ORY90437.1 - 1.3 9.1 6.6 0.82 9.8 1.2 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf PADR1 PF08063.12 ORY90437.1 - 1.6 8.6 10.5 5.7 6.8 0.1 3.6 3 1 0 3 3 3 0 PADR1 (NUC008) domain Lar_restr_allev PF14354.6 ORY90437.1 - 1.7 9.1 13.0 0.19 12.1 2.6 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf_UBZ PF18439.1 ORY90437.1 - 3.5 7.3 0.0 3.5 7.3 0.0 3.6 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger zf-HYPF PF07503.12 ORY90437.1 - 3.7 7.4 11.1 5 7.0 0.1 3.7 4 0 0 4 4 4 0 HypF finger zf-RRN7 PF11781.8 ORY90437.1 - 3.9 7.3 8.8 21 4.9 3.0 3.4 3 1 0 3 3 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L32p PF01783.23 ORY90437.1 - 3.9 7.8 7.7 52 4.2 4.3 3.6 3 1 0 3 3 3 0 Ribosomal L32p protein family PhnA_Zn_Ribbon PF08274.12 ORY90437.1 - 5 7.2 17.8 12 6.0 6.0 3.8 2 2 1 3 3 3 0 PhnA Zinc-Ribbon zf-ZPR1 PF03367.13 ORY90437.1 - 5 6.9 8.2 0.44 10.4 0.9 2.3 2 1 0 2 2 2 0 ZPR1 zinc-finger domain zinc_ribbon_15 PF17032.5 ORY90437.1 - 6 7.7 15.8 1.5e+02 3.2 0.3 3.7 1 1 1 2 2 1 0 zinc-ribbon family UCH PF00443.29 ORY90438.1 - 6.2e-47 160.3 0.0 8.2e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY90438.1 - 3.7e-24 85.9 0.1 5.6e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CpXC PF14353.6 ORY90438.1 - 0.25 11.4 2.2 0.64 10.1 1.0 2.2 1 1 2 3 3 3 0 CpXC protein DZR PF12773.7 ORY90438.1 - 8.3 6.5 7.2 44 4.2 0.2 3.1 2 1 0 2 2 2 0 Double zinc ribbon Sod_Fe_C PF02777.18 ORY90439.1 - 4.8e-40 135.8 0.2 9.7e-40 134.9 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORY90439.1 - 7.2e-31 106.5 3.2 1.4e-30 105.6 3.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DNA_topoisoIV PF00521.20 ORY90440.1 - 2.6e-112 375.8 0.4 4.5e-112 375.1 0.4 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ORY90440.1 - 3.5e-46 156.6 3.7 3.5e-46 156.6 3.7 2.8 4 0 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ORY90440.1 - 1.6e-26 92.9 1.4 1.6e-26 92.9 1.4 1.9 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 ORY90440.1 - 1e-13 51.7 0.1 2.6e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ORY90440.1 - 6.6e-07 29.5 0.0 3e-06 27.4 0.0 2.2 1 0 0 1 1 1 1 Toprim domain F-box-like PF12937.7 ORY90441.1 - 2.2e-09 37.0 2.4 4.8e-09 36.0 2.4 1.6 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 ORY90443.1 - 3e-47 161.2 0.0 5.1e-44 150.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90443.1 - 2.4e-16 59.8 0.0 2.4e-13 50.0 0.0 3.2 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY90443.1 - 3.4e-06 26.1 7.7 3.6e-05 22.7 7.6 2.2 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY90443.1 - 0.0003 20.2 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY90443.1 - 0.00036 20.2 0.1 0.00064 19.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY90443.1 - 0.002 18.1 0.1 0.0053 16.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY90443.1 - 0.0047 16.5 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase UMP1 PF05348.11 ORY90443.1 - 0.013 15.7 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 CDC45 PF02724.14 ORY90443.1 - 0.053 11.8 13.0 0.11 10.8 13.0 1.4 1 1 0 1 1 1 0 CDC45-like protein FTA2 PF13095.6 ORY90443.1 - 0.1 12.2 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HA2 PF04408.23 ORY90445.1 - 2.3e-20 72.9 0.9 4.9e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY90445.1 - 3.8e-12 46.5 0.0 7.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY90445.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY90445.1 - 4.7e-06 27.0 0.0 2.3e-05 24.8 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 ORY90445.1 - 0.00034 20.9 0.1 0.0014 18.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 ORY90445.1 - 0.0033 17.1 0.3 0.023 14.3 0.3 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 ORY90445.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 ORY90445.1 - 0.0093 15.2 0.0 0.078 12.2 0.0 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 ORY90445.1 - 0.019 14.5 0.0 0.13 11.7 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein OB_NTP_bind PF07717.16 ORY90445.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_30 PF13604.6 ORY90445.1 - 0.044 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 ORY90445.1 - 0.058 13.4 0.1 3.8 7.5 0.0 2.5 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORY90445.1 - 0.13 11.8 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Septin PF00735.18 ORY90445.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Septin Esterase PF00756.20 ORY90446.1 - 1.1e-59 202.2 0.0 1.3e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY90446.1 - 6.7e-08 32.3 0.0 9.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ORY90446.1 - 4e-07 29.2 0.0 5.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ORY90446.1 - 6.5e-05 22.3 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY90446.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 ORY90446.1 - 0.0029 16.2 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 ORY90446.1 - 0.0083 15.2 0.0 0.19 10.7 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Esterase_phd PF10503.9 ORY90446.1 - 0.0092 15.5 0.0 0.037 13.5 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 ORY90446.1 - 0.0094 16.6 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY90446.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 ORY90446.1 - 0.053 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 ORY90446.1 - 0.057 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.12 ORY90446.1 - 0.057 13.3 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_S15 PF02129.18 ORY90446.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORY90446.1 - 0.08 11.6 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ORY90446.1 - 0.089 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tyr-DNA_phospho PF06087.12 ORY90447.1 - 2.8e-108 362.6 0.0 3.3e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase His_Phos_2 PF00328.22 ORY90448.1 - 9.6e-30 104.2 0.2 1.3e-29 103.7 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF5375 PF17345.2 ORY90448.1 - 0.015 15.2 0.2 0.039 13.8 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5375) EHN PF06441.12 ORY90449.1 - 1.7e-26 92.7 0.3 4e-26 91.5 0.3 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY90449.1 - 1.1e-14 54.7 0.1 1.9e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY90449.1 - 3.5e-08 34.3 0.4 6.9e-08 33.4 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ACBP PF00887.19 ORY90450.1 - 2.5e-32 110.9 1.3 2.7e-32 110.8 1.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein ACBP PF00887.19 ORY90451.1 - 3.6e-12 46.3 0.6 4.2e-12 46.1 0.6 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Oxysterol_BP PF01237.18 ORY90452.1 - 1.1e-45 156.1 0.0 1.3e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein YABBY PF04690.13 ORY90453.1 - 5.2e-14 53.1 2.5 5.5e-14 53.1 2.5 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 ORY90453.1 - 2e-05 24.9 2.2 2.5e-05 24.6 2.2 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box Ccdc124 PF06244.12 ORY90453.1 - 0.00041 20.9 4.6 0.00046 20.7 4.6 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 ORY90453.1 - 0.0008 20.0 3.5 0.0009 19.8 3.5 1.2 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.25 ORY90454.1 - 9.7e-76 254.6 0.0 1.3e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90454.1 - 2.3e-35 122.2 0.0 3.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY90454.1 - 7.5e-06 25.0 0.1 2e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY90454.1 - 7.1e-05 22.3 0.0 0.00021 20.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 ORY90454.1 - 0.0033 16.8 0.3 0.0053 16.1 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 ORY90454.1 - 0.01 15.3 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 ORY90454.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY90454.1 - 0.093 12.3 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HRG PF16954.5 ORY90455.1 - 0.043 14.2 0.5 0.076 13.4 0.5 1.4 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene CPSase_L_D2 PF02786.17 ORY90456.1 - 6.8e-63 212.0 0.0 1.3e-62 211.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY90456.1 - 1.9e-32 112.1 0.3 1.8e-31 108.9 0.1 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY90456.1 - 6.5e-30 103.4 0.0 2.4e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY90456.1 - 4.4e-16 58.5 2.3 5.4e-15 55.0 2.1 2.8 4 0 0 4 4 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ORY90456.1 - 3.6e-10 39.5 1.5 1.4e-05 24.9 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ORY90456.1 - 4.9e-09 36.0 0.0 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 ORY90456.1 - 1.4e-07 32.2 0.4 0.013 16.2 0.2 3.0 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.22 ORY90456.1 - 1.5e-07 31.2 0.0 5.4e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 ORY90456.1 - 4.7e-06 26.0 0.3 0.0051 16.0 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 ORY90456.1 - 0.00087 19.4 0.0 0.0023 18.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 ORY90456.1 - 0.014 15.3 1.1 0.09 12.7 0.4 2.7 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 ORY90456.1 - 0.034 13.6 0.3 0.072 12.5 0.3 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_ST PF14397.6 ORY90456.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 ORY90456.1 - 0.074 12.8 0.1 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon GSH-S_ATP PF02955.16 ORY90456.1 - 0.12 11.7 0.0 0.43 10.0 0.0 1.8 1 1 1 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain LEA_2 PF03168.13 ORY90456.1 - 0.13 12.8 0.0 0.68 10.5 0.0 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein Neil1-DNA_bind PF09292.10 ORY90457.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind Chitin_synth_2 PF03142.15 ORY90463.1 - 2.6e-236 785.3 2.9 3e-236 785.1 2.2 1.4 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 ORY90463.1 - 7.1e-129 431.0 1.2 5.3e-128 428.1 1.2 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY90463.1 - 9.2e-19 67.1 0.0 1.1e-17 63.7 0.0 2.4 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 ORY90463.1 - 3.5e-14 52.7 0.6 1.9e-07 31.1 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 ORY90463.1 - 1.7e-11 44.5 0.0 5.1e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY90463.1 - 3.3e-10 40.2 3.1 3.3e-10 40.2 3.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY90463.1 - 0.0021 17.9 0.0 0.58 9.9 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY90463.1 - 0.021 14.3 0.2 0.065 12.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 T2SSE PF00437.20 ORY90463.1 - 0.029 13.5 0.1 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 ORY90463.1 - 0.042 14.1 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 ORY90464.1 - 7.7e-05 22.5 0.9 0.00015 21.5 0.9 1.6 1 0 0 1 1 1 1 F-box-like DUF870 PF05912.11 ORY90464.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) DisA-linker PF10635.9 ORY90464.1 - 0.12 12.2 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region F-box PF00646.33 ORY90464.1 - 0.13 12.2 4.0 2.1 8.3 4.0 2.9 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 ORY90464.1 - 0.19 12.2 5.6 2.1 8.9 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_hydro_18 PF00704.28 ORY90465.1 - 3.9e-45 154.9 0.0 5e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5419 PF17441.2 ORY90465.1 - 0.061 13.4 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5419) PFK PF00365.20 ORY90465.1 - 0.066 12.5 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase Beach PF02138.18 ORY90466.1 - 2.6e-121 404.3 0.0 4.9e-121 403.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 ORY90466.1 - 1e-12 48.0 0.0 3.6e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FYVE PF01363.21 ORY90466.1 - 3.4e-12 46.3 14.2 6.8e-12 45.4 14.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 ORY90466.1 - 8.9e-09 35.9 4.8 4.6e-05 24.1 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4704 PF15787.5 ORY90466.1 - 1.7e-08 34.1 2.1 1.8e-07 30.7 0.1 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 ORY90466.1 - 7e-07 29.5 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 ORY90466.1 - 2.9e-05 23.5 4.3 6.1e-05 22.4 4.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) IBR PF01485.21 ORY90466.1 - 0.99 9.7 10.0 2.5 8.4 10.0 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF1772 PF08592.11 ORY90471.1 - 1.1e-21 77.6 0.7 1.3e-21 77.4 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) RCC1 PF00415.18 ORY90476.1 - 7.2e-19 68.2 8.9 6e-06 26.8 0.0 6.7 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY90476.1 - 1.2e-15 56.8 16.6 5.3e-07 29.3 0.5 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 ORY90476.1 - 8.1e-09 35.3 1.8 2.1e-08 33.9 1.8 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY90476.1 - 0.00053 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 ORY90476.1 - 0.0046 16.8 0.4 0.011 15.6 0.4 1.7 1 0 0 1 1 1 1 F-box domain zf-C2H2_4 PF13894.6 ORY90477.1 - 0.37 11.8 13.3 0.61 11.1 0.6 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 ORY90477.1 - 0.54 10.7 3.1 3.4 8.2 0.1 2.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Abhydrolase_1 PF00561.20 ORY90481.1 - 2.5e-22 79.7 0.1 6.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY90481.1 - 2.3e-21 76.2 0.0 3.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY90481.1 - 1.8e-18 68.0 0.2 2.6e-18 67.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY90481.1 - 0.00039 20.0 0.2 0.79 9.2 0.1 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 ORY90481.1 - 0.00045 20.0 0.1 0.0061 16.3 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ORY90481.1 - 0.0017 18.5 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 ORY90481.1 - 0.002 18.2 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 ORY90481.1 - 0.029 14.3 0.1 0.11 12.4 0.0 2.0 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ORY90481.1 - 0.11 12.0 0.1 0.54 9.7 0.0 2.2 2 1 1 3 3 3 0 Prolyl oligopeptidase family FSH1 PF03959.13 ORY90481.1 - 0.14 11.8 0.1 0.7 9.5 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) F-box PF00646.33 ORY90482.1 - 8.7e-08 31.9 1.2 8.7e-08 31.9 1.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY90482.1 - 9.1e-05 22.3 1.9 0.00012 21.9 0.4 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY90482.1 - 0.074 13.5 16.9 0.44 11.1 0.4 5.6 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 ORY90482.1 - 0.092 12.4 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Noc2 PF03715.13 ORY90483.1 - 3.4e-94 315.5 0.7 7.5e-94 314.3 0.7 1.5 1 0 0 1 1 1 1 Noc2p family DUF4334 PF14232.6 ORY90484.1 - 2.4e-24 85.0 0.5 1.7e-23 82.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 ORY90484.1 - 3.5e-23 81.5 0.2 4.9e-23 81.0 0.2 1.2 1 0 0 1 1 1 1 GXWXG protein Lzipper-MIP1 PF14389.6 ORY90485.1 - 0.019 15.3 1.1 0.053 13.8 1.1 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 betaPIX_CC PF16523.5 ORY90485.1 - 0.023 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 betaPIX coiled coil Response_reg PF00072.24 ORY90486.1 - 5.1e-22 78.2 0.1 1.7e-15 57.2 0.2 2.6 2 0 0 2 2 2 2 Response regulator receiver domain 7TMR-DISM_7TM PF07695.11 ORY90486.1 - 0.11 12.3 8.2 0.2 11.6 8.2 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling GATA PF00320.27 ORY90487.1 - 7.8e-31 105.4 15.4 5e-16 58.0 4.1 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 ORY90487.1 - 3.7e-12 45.9 1.9 1e-11 44.5 1.9 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 ORY90487.1 - 6.4e-05 23.0 1.8 0.22 11.6 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORY90487.1 - 0.001 18.5 4.3 0.085 12.4 0.3 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 ORY90487.1 - 0.01 15.9 7.9 0.07 13.2 5.4 3.0 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 ORY90487.1 - 0.011 15.6 4.2 1.6 8.6 0.6 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 HsbA PF12296.8 ORY90487.1 - 0.031 14.7 2.8 0.058 13.8 2.2 1.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Auto_anti-p27 PF06677.12 ORY90487.1 - 0.034 14.3 6.1 1.4 9.1 0.4 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OTT_1508_deam PF14441.6 ORY90487.1 - 0.091 12.8 0.9 12 6.0 0.1 2.8 2 0 0 2 2 2 0 OTT_1508-like deaminase DUF2387 PF09526.10 ORY90487.1 - 0.14 12.4 1.9 1.3 9.2 0.3 2.7 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) OrfB_Zn_ribbon PF07282.11 ORY90487.1 - 0.16 11.9 5.3 1 9.4 0.5 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Vps36-NZF-N PF16988.5 ORY90487.1 - 0.19 11.2 5.7 2.3 7.7 0.1 3.6 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-ribbon_3 PF13248.6 ORY90487.1 - 0.4 10.2 7.3 5 6.7 0.1 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 ORY90487.1 - 0.45 10.6 5.0 23 5.1 0.2 3.6 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger Rpr2 PF04032.16 ORY90487.1 - 0.96 9.8 5.5 4.9 7.5 2.9 3.1 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_15 PF17032.5 ORY90487.1 - 2.1 9.2 5.5 49 4.8 3.5 2.9 1 1 2 3 3 3 0 zinc-ribbon family FAM163 PF15069.6 ORY90487.1 - 6.2 7.2 12.9 1.3 9.4 2.8 3.3 2 1 1 3 3 3 0 FAM163 family zf-B_box PF00643.24 ORY90487.1 - 7.1 6.9 10.6 17 5.6 1.7 3.6 2 2 0 2 2 2 0 B-box zinc finger PRK PF00485.18 ORY90494.1 - 3.9e-29 101.8 0.0 4.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 ORY90494.1 - 0.052 14.1 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pesticin PF16754.5 ORY90494.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term RRM_1 PF00076.22 ORY90495.1 - 1.5e-19 69.6 0.0 1.4e-13 50.4 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY90495.1 - 0.015 15.4 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif PAT1 PF09770.9 ORY90495.1 - 1.4 7.1 18.3 2.3 6.4 18.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.19 ORY90495.1 - 1.9 8.3 21.3 1.5 8.7 1.0 2.1 2 0 0 2 2 2 0 SPX domain DUF4527 PF15030.6 ORY90495.1 - 2.7 7.3 14.3 0.52 9.7 10.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Pyr_redox_2 PF07992.14 ORY90496.1 - 5.7e-38 130.8 0.0 7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY90496.1 - 1.3e-15 57.7 0.2 3e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY90496.1 - 3e-10 40.3 1.7 0.11 12.5 0.0 4.1 3 1 1 4 4 4 4 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY90496.1 - 2.2e-09 37.0 0.0 2.6e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY90496.1 - 1.3e-06 27.4 2.5 0.0022 16.7 0.0 3.8 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 ORY90496.1 - 4.2e-06 26.1 0.0 0.00023 20.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY90496.1 - 2.2e-05 24.2 4.4 0.00012 21.8 4.4 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY90496.1 - 2.8e-05 24.3 0.4 0.00035 20.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY90496.1 - 5.9e-05 22.1 0.4 0.00066 18.7 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 ORY90496.1 - 0.00026 20.3 0.2 0.082 12.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ORY90496.1 - 0.0042 16.2 0.1 4.9 6.1 0.0 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein DUF3236 PF11576.8 ORY90496.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Thi4 PF01946.17 ORY90496.1 - 0.056 12.7 0.1 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 ORY90496.1 - 0.11 12.8 0.1 5.6 7.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 ORY90496.1 - 0.14 12.6 0.0 2.3 8.7 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 ORY90496.1 - 0.22 10.6 0.2 0.53 9.3 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 ORY90496.1 - 0.51 9.6 2.8 1.5 8.0 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY90496.1 - 0.63 9.1 4.4 0.67 9.0 0.1 2.8 3 1 0 4 4 4 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ORY90497.1 - 1.5e-34 119.5 0.1 2e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY90497.1 - 5.8e-14 52.4 1.6 1.7e-09 38.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY90497.1 - 6.4e-09 35.5 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY90497.1 - 2.9e-08 33.8 0.5 0.32 11.0 0.1 4.1 3 1 1 4 4 4 3 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORY90497.1 - 4e-08 32.8 0.4 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ORY90497.1 - 3.6e-05 22.7 0.5 0.81 8.3 0.1 3.5 3 1 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 ORY90497.1 - 0.00028 21.0 0.2 0.0046 17.2 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 ORY90497.1 - 0.00033 20.9 0.6 0.034 14.4 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain Trp_halogenase PF04820.14 ORY90497.1 - 0.00047 19.1 1.8 0.00054 18.9 0.2 1.9 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 ORY90497.1 - 0.0012 18.0 0.5 1.2 8.1 0.1 2.8 2 1 1 3 3 3 2 Lycopene cyclase protein Thi4 PF01946.17 ORY90497.1 - 0.0017 17.6 0.1 1.6 7.9 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Sacchrp_dh_NADP PF03435.18 ORY90497.1 - 0.0021 18.3 0.7 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 ORY90497.1 - 0.0037 17.7 0.1 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 ORY90497.1 - 0.0039 16.8 6.9 0.027 14.1 6.9 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF3236 PF11576.8 ORY90497.1 - 0.015 15.0 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) FAD_oxidored PF12831.7 ORY90497.1 - 0.042 13.2 3.6 0.29 10.4 0.2 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORY90497.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ORY90497.1 - 0.17 11.1 1.0 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 ORY90497.1 - 0.18 10.9 0.5 0.34 9.9 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY90497.1 - 3.6 6.6 6.2 0.41 9.7 0.3 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-C4_ClpX PF06689.13 ORY90498.1 - 0.0032 17.3 0.2 0.0071 16.2 0.2 1.6 1 0 0 1 1 1 1 ClpX C4-type zinc finger LSM PF01423.22 ORY90499.1 - 5.5e-10 38.8 0.1 6.7e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY90499.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Septin PF00735.18 ORY90500.1 - 4.7e-109 364.0 0.4 5.7e-109 363.8 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY90500.1 - 4.3e-09 36.5 0.1 2.4e-08 34.0 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY90500.1 - 2e-07 31.1 0.4 3.6e-06 27.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 ORY90500.1 - 7.5e-06 25.4 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 ORY90500.1 - 2.1e-05 24.2 0.1 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORY90500.1 - 0.00024 21.5 0.0 0.00068 20.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 ORY90500.1 - 0.00082 19.5 0.6 0.64 10.1 0.2 2.5 1 1 1 2 2 2 2 Dynamin family Gtr1_RagA PF04670.12 ORY90500.1 - 0.0011 18.3 0.4 0.017 14.5 0.0 2.2 1 1 0 2 2 2 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 ORY90500.1 - 0.0018 17.5 0.1 0.0037 16.5 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 ORY90500.1 - 0.0025 18.1 0.0 0.006 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY90500.1 - 0.0036 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.27 ORY90500.1 - 0.0052 17.3 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 ORY90500.1 - 0.0075 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORY90500.1 - 0.0099 15.4 0.2 0.031 13.8 0.1 1.9 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 ORY90500.1 - 0.017 15.2 0.1 0.11 12.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 ORY90500.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 ORY90500.1 - 0.033 13.4 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 ORY90500.1 - 0.034 13.2 0.1 0.093 11.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.22 ORY90500.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Ras family AAA_32 PF13654.6 ORY90500.1 - 0.056 12.2 0.1 0.11 11.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY90500.1 - 0.07 12.9 0.2 0.19 11.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ORY90500.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 ORY90500.1 - 0.2 10.8 2.1 0.56 9.3 2.1 2.1 1 1 0 1 1 1 0 G-protein alpha subunit Aha1_N PF09229.11 ORY90501.1 - 1.3e-40 138.8 0.5 1.5e-40 138.6 0.5 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF2183 PF09949.9 ORY90502.1 - 4.1e-35 120.1 0.3 1.1e-34 118.7 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 ORY90502.1 - 0.0045 16.5 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Cactin_mid PF10312.9 ORY90503.1 - 2.4e-65 220.0 10.8 2.4e-65 220.0 10.8 2.4 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 ORY90503.1 - 1.1e-60 203.1 7.8 2.1e-60 202.2 7.8 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein QLQ PF08880.11 ORY90503.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 QLQ Amino_oxidase PF01593.24 ORY90503.1 - 5.7 6.1 8.1 0.59 9.4 2.8 2.0 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Mg_trans_NIPA PF05653.14 ORY90504.1 - 2.5e-19 69.5 12.3 1.8e-10 40.4 2.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA SARAF PF06682.12 ORY90504.1 - 0.0023 17.7 0.1 0.0055 16.4 0.1 1.6 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis EamA PF00892.20 ORY90504.1 - 0.015 15.5 3.3 0.015 15.5 3.3 2.9 3 0 0 3 3 3 0 EamA-like transporter family Mito_fiss_reg PF05308.11 ORY90504.1 - 0.07 13.2 7.0 0.11 12.5 7.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Trp_oprn_chp PF09534.10 ORY90504.1 - 0.075 12.8 0.0 0.74 9.6 0.0 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 ORY90504.1 - 0.79 9.6 3.9 10 6.1 0.0 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain HlyIII PF03006.20 ORY90504.1 - 4.9 6.8 11.5 1.6 8.4 3.4 2.4 1 1 0 2 2 2 0 Haemolysin-III related Gpi1 PF05024.15 ORY90505.1 - 8e-70 234.7 12.8 1.6e-69 233.7 12.8 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) tRNA-synt_1 PF00133.22 ORY90506.1 - 1.1e-219 730.7 0.0 2.1e-218 726.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY90506.1 - 1.5e-36 125.6 0.0 3.4e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY90506.1 - 9e-17 60.9 0.0 1.1e-08 34.3 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORY90506.1 - 2.4e-08 33.7 9.7 1.6e-07 31.0 0.1 3.5 2 1 2 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ORY90506.1 - 0.003 17.0 0.0 0.13 11.5 0.0 2.8 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain WD40 PF00400.32 ORY90507.1 - 8.4e-13 48.6 14.0 0.00012 22.8 1.2 8.8 10 0 0 10 10 10 5 WD domain, G-beta repeat Ribosomal_L36 PF00444.18 ORY90508.1 - 2.6e-17 62.7 10.3 4.4e-17 62.0 10.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 Oxidored_FMN PF00724.20 ORY90509.1 - 2.6e-100 336.1 0.0 2.9e-100 335.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4229 PF14012.6 ORY90510.1 - 0.018 15.1 1.0 3 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Colicin_V PF02674.16 ORY90510.1 - 0.047 13.7 1.1 1.2 9.1 0.4 2.2 2 0 0 2 2 2 0 Colicin V production protein DUF4055 PF13264.6 ORY90510.1 - 0.15 12.2 1.6 0.53 10.4 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4055) DUF3720 PF12517.8 ORY90510.1 - 5.3 8.1 11.1 4.1 8.4 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3720) TAP42 PF04177.12 ORY90511.1 - 3.5e-96 322.1 8.8 4e-96 321.9 8.8 1.0 1 0 0 1 1 1 1 TAP42-like family Pribosyltran PF00156.27 ORY90512.1 - 5.1e-15 55.3 0.0 6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1256 PF06866.11 ORY90512.1 - 0.0067 15.9 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1256) UPRTase PF14681.6 ORY90512.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.4 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Propeptide_C1 PF08127.13 ORY90512.1 - 0.025 14.5 0.7 0.65 9.9 0.0 2.8 3 0 0 3 3 3 0 Peptidase family C1 propeptide tRNA_bind PF01588.20 ORY90513.1 - 2.3e-26 91.7 0.0 4.4e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.6 ORY90513.1 - 1.7e-06 28.1 0.0 1.7e-06 28.1 0.0 2.3 3 1 0 3 3 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY90513.1 - 2e-06 27.9 0.0 2e-06 27.9 0.0 3.1 2 2 1 3 3 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY90513.1 - 3.8e-05 23.6 0.0 0.0001 22.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNA_pol_Rpc4 PF05132.14 ORY90513.1 - 0.0086 16.5 6.7 0.015 15.8 6.7 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 Glutaredoxin2_C PF04399.13 ORY90513.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FancD2 PF14631.6 ORY90513.1 - 0.35 8.2 2.9 0.42 7.9 2.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease NARP1 PF12569.8 ORY90513.1 - 0.43 9.4 10.4 0.68 8.8 10.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 ORY90513.1 - 2.5 7.9 9.6 4 7.2 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 ORY90513.1 - 4.6 6.6 8.3 6.9 6.0 8.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 ORY90513.1 - 7.3 5.3 9.0 11 4.7 9.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 ORY90513.1 - 10 4.3 10.0 14 3.8 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Fer4 PF00037.27 ORY90514.1 - 2.2e-14 52.6 16.4 1.8e-08 33.8 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ORY90514.1 - 6.5e-13 49.1 10.4 1.2e-12 48.2 10.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ORY90514.1 - 3.4e-10 40.7 7.3 5.4e-05 24.1 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ORY90514.1 - 2.3e-09 37.2 6.7 0.00014 21.9 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY90514.1 - 9.7e-09 35.2 21.2 4.7e-06 26.6 12.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ORY90514.1 - 1.1e-08 35.1 10.2 1.8e-08 34.4 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ORY90514.1 - 3.8e-07 29.9 17.8 0.0004 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 ORY90514.1 - 9.2e-07 29.2 19.3 0.00044 20.6 11.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ORY90514.1 - 1.4e-06 28.1 12.5 0.0028 17.7 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ORY90514.1 - 1.2e-05 25.4 11.8 0.00052 20.3 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ORY90514.1 - 0.00035 21.0 11.4 0.047 14.3 12.5 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 ORY90514.1 - 0.0005 20.6 10.2 0.087 13.4 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 ORY90514.1 - 0.029 14.6 5.9 1.3 9.3 0.3 2.4 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 ORY90514.1 - 0.049 13.8 8.8 12 6.1 8.9 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain ETF_QO PF05187.13 ORY90514.1 - 0.21 11.7 5.9 1.8 8.7 1.1 2.4 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 ORY90514.1 - 0.22 12.5 16.3 0.35 11.9 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 ORY90514.1 - 0.78 10.6 11.9 3.2 8.6 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Ribosomal_S5_C PF03719.15 ORY90515.1 - 3.5e-26 90.4 0.0 1.2e-24 85.6 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ORY90515.1 - 1.1e-20 73.4 1.1 1.9e-20 72.6 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Arabino_trans_C PF14896.6 ORY90515.1 - 0.091 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain zf-C2H2 PF00096.26 ORY90516.1 - 2.2e-10 40.4 26.4 0.00022 21.5 2.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY90516.1 - 3.8e-07 30.4 23.6 0.014 16.2 1.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY90516.1 - 1.3e-06 28.5 36.8 6.6e-05 23.2 6.8 5.6 5 1 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORY90516.1 - 0.016 14.9 18.9 0.94 9.3 0.2 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain HTH_33 PF13592.6 ORY90516.1 - 0.24 11.1 1.2 19 5.0 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix FOXP-CC PF16159.5 ORY90516.1 - 0.39 11.4 6.7 3.2 8.4 0.1 2.7 3 0 0 3 3 3 0 FOXP coiled-coil domain Proteasome PF00227.26 ORY90517.1 - 2.3e-44 151.2 0.0 2.6e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MS_channel PF00924.18 ORY90518.1 - 2.1e-17 63.4 0.7 3.6e-17 62.6 0.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 ORY90518.1 - 2.1e-05 23.8 0.1 5.5e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORY90518.1 - 0.00015 21.4 0.1 0.00047 19.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORY90518.1 - 0.00039 19.8 0.1 0.00095 18.6 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORY90518.1 - 0.0077 16.7 0.1 0.019 15.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY90518.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF2207 PF09972.9 ORY90518.1 - 0.39 9.4 6.4 2.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4271 PF14093.6 ORY90518.1 - 2.2 8.1 11.9 2.7 7.8 2.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) HSP90 PF00183.18 ORY90519.1 - 6.4e-234 777.6 26.1 8.3e-234 777.3 26.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORY90519.1 - 1.7e-13 51.1 0.1 3.3e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY90519.1 - 4.4e-11 42.8 0.1 1.1e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 ORY90519.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN EMP70 PF02990.16 ORY90520.1 - 9.8e-156 519.4 15.4 1.3e-155 519.1 15.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Tmemb_18A PF09771.9 ORY90520.1 - 1.2 9.5 4.7 39 4.7 2.4 3.4 3 1 0 3 3 3 0 Transmembrane protein 188 EVC2_like PF12297.8 ORY90520.1 - 3.7 6.1 4.0 34 3.0 0.0 2.1 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Rxt3 PF08642.10 ORY90521.1 - 2.3e-21 76.9 4.8 2.4e-20 73.6 1.2 2.7 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 ORY90521.1 - 0.0003 20.8 0.0 0.0016 18.5 0.0 2.0 1 1 0 1 1 1 1 LCCL domain cwf21 PF08312.12 ORY90522.1 - 3.6e-15 55.8 6.2 3.6e-15 55.8 6.2 2.7 2 1 0 2 2 2 1 cwf21 domain EF1_GNE PF00736.19 ORY90522.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain MCCD1 PF15707.5 ORY90524.1 - 0.053 14.0 0.1 0.093 13.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 His_biosynth PF00977.21 ORY90526.1 - 9.4e-47 159.4 0.0 5.2e-46 156.9 0.0 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 ORY90526.1 - 1.4e-19 70.6 0.0 3.1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ORY90526.1 - 2.3e-10 40.7 0.0 9.3e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORY90526.1 - 5.8e-09 35.8 0.0 1.7e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 ORY90526.1 - 0.0066 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DND1_DSRM PF14709.7 ORY90526.1 - 0.039 14.2 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 NMO PF03060.15 ORY90526.1 - 0.088 12.2 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase ArfGap PF01412.18 ORY90527.1 - 7.6e-42 142.1 1.6 7.6e-42 142.1 1.6 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ras PF00071.22 ORY90528.1 - 4.6e-50 169.4 0.0 5.3e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY90528.1 - 1.9e-21 76.5 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY90528.1 - 5.3e-07 29.3 0.0 7.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY90528.1 - 0.00025 20.6 0.4 0.0013 18.3 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY90528.1 - 0.00038 19.9 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 ORY90528.1 - 0.00083 19.9 0.0 0.0014 19.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 ORY90528.1 - 0.0036 17.4 0.0 0.0086 16.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY90528.1 - 0.0057 17.1 0.0 0.0097 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORY90528.1 - 0.027 13.9 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORY90528.1 - 0.03 14.2 0.2 0.22 11.4 0.1 2.1 1 1 1 3 3 3 0 RsgA GTPase cobW PF02492.19 ORY90528.1 - 0.043 13.4 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORY90528.1 - 0.058 13.3 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 ORY90528.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY90528.1 - 0.14 11.4 0.0 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 ORY90528.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_21 PF13304.6 ORY90528.1 - 0.2 11.4 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY90528.1 - 0.28 11.7 0.0 0.64 10.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain Bestrophin PF01062.21 ORY90529.1 - 1.1e-43 149.8 0.0 3.8e-23 82.3 0.0 2.3 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Polysacc_deac_1 PF01522.21 ORY90530.1 - 4.7e-34 117.0 0.0 8.6e-34 116.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY90530.1 - 0.0032 16.7 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORY90530.1 - 0.19 11.3 1.0 1.1 8.9 0.9 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) NPR2 PF06218.11 ORY90531.1 - 2.8e-114 382.3 5.7 1.2e-90 304.4 9.0 2.9 1 1 1 2 2 2 2 Nitrogen permease regulator 2 zinc-ribbons_6 PF07191.12 ORY90532.1 - 0.11 12.5 7.7 4.1 7.5 8.3 2.2 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 ORY90532.1 - 0.23 11.5 9.4 1.8 8.6 9.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 ORY90532.1 - 0.73 9.5 12.6 8 6.2 2.2 4.1 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger Fer4_10 PF13237.6 ORY90532.1 - 0.89 9.7 9.1 17 5.6 0.0 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Ribosomal_S27 PF01599.19 ORY90532.1 - 2 8.6 10.0 2.3 8.5 5.0 2.7 3 0 0 3 3 3 0 Ribosomal protein S27a Fer4 PF00037.27 ORY90532.1 - 9.3 6.2 9.2 18 5.3 0.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain RPAP1_C PF08620.10 ORY90533.1 - 3.8e-25 87.8 0.0 9.2e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 ORY90533.1 - 5.1e-10 39.0 4.4 5.1e-10 39.0 4.4 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal PG_binding_1 PF01471.18 ORY90533.1 - 0.049 13.9 0.1 3.7 7.8 0.0 3.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DotD PF16816.5 ORY90533.1 - 0.36 10.8 2.4 11 5.9 0.3 2.5 2 0 0 2 2 2 0 DotD protein F-box-like PF12937.7 ORY90534.1 - 0.16 11.9 0.4 0.16 11.9 0.4 2.5 3 0 0 3 3 3 0 F-box-like DUF5323 PF17257.2 ORY90534.1 - 0.19 11.6 2.4 0.32 10.9 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Hairy_orange PF07527.13 ORY90534.1 - 0.3 11.3 4.1 10 6.4 0.1 3.7 4 0 0 4 4 4 0 Hairy Orange Cation_efflux PF01545.21 ORY90535.1 - 1.6e-27 96.5 13.3 2.1e-27 96.1 13.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY90535.1 - 4e-11 42.9 0.0 7.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MIG-14_Wnt-bd PF06664.12 ORY90535.1 - 0.0086 15.3 1.3 0.013 14.7 1.3 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion ABC2_membrane_5 PF13346.6 ORY90535.1 - 0.69 9.4 8.5 1.4 8.5 8.5 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Trep_Strep PF09605.10 ORY90535.1 - 0.9 9.5 8.7 1.1 9.2 7.4 1.8 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) PH_9 PF15410.6 ORY90536.1 - 9.2e-12 45.4 0.0 1.4e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY90536.1 - 7.6e-08 32.8 0.0 1.5e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 PH domain Linker_histone PF00538.19 ORY90537.1 - 1.1e-26 93.0 0.3 1.1e-26 93.0 0.3 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family DUF126 PF01989.16 ORY90537.1 - 0.0012 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain Rib_5-P_isom_A PF06026.14 ORY90538.1 - 2.2e-62 209.7 0.1 2.8e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Zn_clus PF00172.18 ORY90539.1 - 0.00039 20.5 10.1 0.00074 19.6 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.12 ORY90539.1 - 0.00077 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORY90539.1 - 0.0023 17.9 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold CW_binding_2 PF04122.12 ORY90539.1 - 0.48 11.1 3.0 0.73 10.5 0.2 2.3 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 RRM_1 PF00076.22 ORY90540.1 - 2e-27 94.8 0.0 7e-09 35.4 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY90540.1 - 3.3e-08 33.3 0.0 2.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY90540.1 - 7.7e-06 25.5 0.0 0.022 14.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY90540.1 - 0.056 13.5 0.0 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Collagen_bind_2 PF12904.7 ORY90540.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase MAPEG PF01124.18 ORY90541.1 - 8e-05 22.6 7.2 0.00012 22.0 7.2 1.3 1 1 0 1 1 1 1 MAPEG family EF-hand_6 PF13405.6 ORY90543.1 - 8.1e-11 40.9 0.4 4.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY90543.1 - 4.3e-08 32.3 0.8 0.00042 19.7 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 ORY90543.1 - 1.7e-07 31.6 0.4 3.6e-07 30.5 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY90543.1 - 1.9e-07 30.1 0.3 0.00094 18.6 0.1 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 ORY90543.1 - 9.4e-05 22.7 0.1 9.4e-05 22.7 0.1 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 ORY90543.1 - 0.026 14.4 0.1 2.3 8.1 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain pair Topoisom_bac PF01131.20 ORY90544.1 - 2.4e-113 379.3 0.0 2.9e-113 379.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 ORY90544.1 - 3e-17 62.7 0.0 5.4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain SNF2_N PF00176.23 ORY90545.1 - 1.5e-71 241.0 0.4 1.5e-71 241.0 0.4 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 ORY90545.1 - 8.4e-24 83.5 1.4 2.4e-23 82.0 1.4 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 ORY90545.1 - 1.1e-21 77.2 0.1 5.7e-20 71.7 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 ORY90545.1 - 9.5e-18 64.3 14.0 9.5e-18 64.3 14.0 3.3 5 0 0 5 5 5 1 HSA QLQ PF08880.11 ORY90545.1 - 1.4e-13 50.4 6.6 1.4e-13 50.4 6.6 2.4 2 0 0 2 2 2 1 QLQ SnAC PF14619.6 ORY90545.1 - 2.9e-13 50.2 5.9 2.9e-13 50.2 5.9 3.3 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 ORY90545.1 - 4.7e-08 33.2 0.3 2e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY90545.1 - 2.7e-07 30.1 0.0 1.6e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CCDC24 PF15669.5 ORY90546.1 - 1.2 9.0 5.9 1.3 8.8 4.3 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family Macoilin PF09726.9 ORY90546.1 - 2.4 6.6 6.3 2.7 6.5 6.3 1.0 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 ORY90546.1 - 4.9 6.1 10.0 8.1 5.4 10.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X Syntaphilin PF15290.6 ORY90546.1 - 9.5 5.8 14.0 2.9 7.5 10.6 1.7 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp FF PF01846.19 ORY90547.1 - 5.2e-37 125.8 15.7 3e-13 49.7 2.4 3.4 3 0 0 3 3 3 3 FF domain WW PF00397.26 ORY90547.1 - 7.4e-12 45.1 13.3 1.1e-07 31.7 4.7 3.0 3 0 0 3 3 3 2 WW domain Protamine_P2 PF00841.19 ORY90547.1 - 0.043 14.3 0.9 0.043 14.3 0.9 3.9 2 1 0 4 4 4 0 Sperm histone P2 Senescence_reg PF04520.13 ORY90547.1 - 8.5 7.2 18.0 0.37 11.6 10.0 2.5 3 0 0 3 3 3 0 Senescence regulator DUF1664 PF07889.12 ORY90548.1 - 0.0052 16.8 0.7 0.0094 16.0 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) CNTF PF01110.17 ORY90548.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.5 2 0 0 2 2 2 0 Ciliary neurotrophic factor FliD_N PF02465.18 ORY90548.1 - 0.069 13.9 1.0 6.4 7.5 0.5 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Utp11 PF03998.13 ORY90548.1 - 0.072 13.0 0.3 0.069 13.1 0.3 1.1 1 0 0 1 1 1 0 Utp11 protein NPV_P10 PF05531.12 ORY90548.1 - 0.084 13.3 0.6 0.27 11.7 0.2 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spuma_A9PTase PF03539.14 ORY90551.1 - 0.039 14.1 0.1 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) Bacillus_HBL PF05791.11 ORY90553.1 - 0.0076 16.1 1.6 0.011 15.6 1.6 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) APG6_N PF17675.1 ORY90553.1 - 0.0085 16.6 3.0 0.012 16.1 3.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region YabA PF06156.13 ORY90553.1 - 0.019 15.6 0.7 0.028 15.0 0.7 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF881 PF05949.12 ORY90553.1 - 0.021 14.7 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) TBCC_N PF16752.5 ORY90553.1 - 0.022 15.2 2.8 0.038 14.4 2.8 1.3 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain NRBF2 PF08961.10 ORY90553.1 - 0.024 14.2 1.7 0.043 13.4 1.7 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Yuri_gagarin PF15934.5 ORY90553.1 - 0.025 14.4 0.1 0.032 14.1 0.1 1.1 1 0 0 1 1 1 0 Yuri gagarin Med9 PF07544.13 ORY90553.1 - 0.038 14.1 2.5 0.064 13.4 2.5 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 KxDL PF10241.9 ORY90553.1 - 0.097 13.0 3.5 0.15 12.3 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF3450 PF11932.8 ORY90553.1 - 0.1 11.8 6.6 0.15 11.3 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1843 PF08898.10 ORY90553.1 - 0.13 12.8 3.3 0.27 11.8 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Exo_endo_phos_2 PF14529.6 ORY90554.1 - 4e-13 49.2 0.1 2.6e-12 46.6 0.2 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 ORY90554.1 - 9.5e-06 25.3 0.6 2.3e-05 24.0 0.6 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDE_Tnp_ISL3 PF01610.17 ORY90554.1 - 2.2 7.9 5.3 0.6 9.8 2.3 1.5 2 0 0 2 2 2 0 Transposase DUF4939 PF16297.5 ORY90555.1 - 1.2e-07 31.6 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF1043 PF06295.12 ORY90555.1 - 0.012 15.6 0.7 0.024 14.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) S_locus_glycop PF00954.20 ORY90555.1 - 0.14 12.7 0.6 0.27 11.8 0.6 1.4 1 0 0 1 1 1 0 S-locus glycoprotein domain Phage_int_SAM_4 PF13495.6 ORY90557.1 - 0.0016 18.8 0.0 0.0065 16.9 0.0 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 ORY90557.1 - 0.0021 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF4218 PF13960.6 ORY90558.1 - 0.0058 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pr_beta_C PF12465.8 ORY90558.1 - 0.35 10.3 2.2 0.38 10.2 0.5 2.0 2 0 0 2 2 2 0 Proteasome beta subunits C terminal zf-BED PF02892.15 ORY90558.1 - 0.56 10.3 1.7 0.79 9.8 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger zf-Tim10_DDP PF02953.15 ORY90560.1 - 3.6e-18 64.9 2.8 5.3e-18 64.4 2.8 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 ORY90560.1 - 0.0056 16.9 0.1 0.14 12.4 0.1 2.0 1 1 1 2 2 2 1 Phasin protein DUF842 PF05811.13 ORY90560.1 - 0.04 13.6 2.5 0.072 12.8 2.3 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) zf-RING_2 PF13639.6 ORY90561.1 - 4.1e-09 36.6 10.7 7.5e-09 35.8 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY90561.1 - 4.8e-06 26.3 11.3 8.3e-06 25.6 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY90561.1 - 7.7e-06 26.1 16.9 0.00022 21.5 16.9 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY90561.1 - 1.2e-05 25.1 7.5 2.1e-05 24.3 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY90561.1 - 1.2e-05 24.9 4.0 2.7e-05 23.8 4.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY90561.1 - 1.5e-05 24.9 9.4 0.00019 21.4 9.7 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY90561.1 - 4.7e-05 23.2 8.2 7.6e-05 22.5 8.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY90561.1 - 0.0001 22.2 9.2 0.00023 21.1 9.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY90561.1 - 0.0004 20.1 11.4 0.00072 19.4 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY90561.1 - 0.002 18.2 6.5 0.0034 17.5 6.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING YdjO PF14169.6 ORY90561.1 - 0.013 15.2 1.2 2.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_5 PF14634.6 ORY90561.1 - 0.031 14.2 9.7 0.058 13.4 9.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 ORY90561.1 - 0.068 13.0 2.7 0.16 11.8 2.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Neur_chan_memb PF02932.16 ORY90561.1 - 0.14 12.2 0.7 0.47 10.5 0.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RINGv PF12906.7 ORY90561.1 - 0.15 12.2 8.8 0.39 10.9 8.8 1.7 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 ORY90561.1 - 0.47 10.1 9.8 0.92 9.2 9.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 ORY90561.1 - 0.53 10.6 10.6 1.1 9.6 10.6 1.6 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 ORY90561.1 - 0.59 10.4 8.8 2.7 8.2 8.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 ORY90561.1 - 0.79 9.9 0.0 0.79 9.9 0.0 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 Arm PF00514.23 ORY90562.1 - 1e-05 25.3 2.7 0.011 15.8 0.0 4.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY90562.1 - 0.00017 22.0 1.3 0.03 14.8 0.1 4.9 6 1 0 6 6 6 1 HEAT-like repeat Cnd3 PF12719.7 ORY90562.1 - 0.0013 18.0 0.3 3.2 6.9 0.0 3.4 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain ParcG PF10274.9 ORY90562.1 - 0.027 14.6 0.3 0.49 10.5 0.0 3.0 3 1 1 4 4 4 0 Parkin co-regulated protein Ric8 PF10165.9 ORY90562.1 - 0.029 13.4 1.1 8.9 5.2 0.0 3.2 3 1 0 3 3 3 0 Guanine nucleotide exchange factor synembryn Cnd1 PF12717.7 ORY90562.1 - 0.045 13.8 0.0 0.19 11.7 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY90562.1 - 0.082 13.2 2.4 25 5.5 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat DUF1752 PF08550.10 ORY90563.1 - 2.8e-12 46.2 1.7 5.5e-12 45.3 1.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Inj_translocase PF16928.5 ORY90563.1 - 0.009 15.5 1.0 0.015 14.8 1.0 1.2 1 0 0 1 1 1 1 DNA/protein translocase of phage P22 injectosome ADH_zinc_N PF00107.26 ORY90564.1 - 1e-17 64.4 0.0 1.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY90564.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY90564.1 - 6e-05 24.1 0.0 0.00032 21.7 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 ORY90565.1 - 1.4e-86 289.6 0.5 4.4e-86 288.0 0.2 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY90565.1 - 3e-16 59.9 0.0 7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY90565.1 - 6.7e-15 55.5 0.1 2.2e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY90565.1 - 2.3e-12 47.0 0.0 3.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY90565.1 - 2.9e-12 47.2 0.0 5.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY90565.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY90565.1 - 0.00048 19.7 0.0 0.00095 18.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_28 PF02636.17 ORY90565.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 ORY90565.1 - 0.0068 16.3 0.1 0.089 12.6 0.0 2.4 1 1 2 3 3 3 1 Hypothetical methyltransferase Methyltransf_5 PF01795.19 ORY90565.1 - 0.018 14.6 0.0 2 7.8 0.0 2.1 1 1 1 2 2 2 0 MraW methylase family ADH_zinc_N PF00107.26 ORY90565.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CH PF00307.31 ORY90566.1 - 2.5e-84 278.6 0.4 3.3e-20 72.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY90566.1 - 5.8e-11 42.1 0.0 0.0076 16.1 0.0 4.2 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.6 ORY90566.1 - 3.9e-07 30.4 0.2 1.2e-06 28.8 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY90566.1 - 5.5e-06 25.9 0.3 0.00021 20.9 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 ORY90566.1 - 7.3e-06 25.2 0.5 0.0038 16.7 0.1 3.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 ORY90566.1 - 0.0015 17.9 0.9 0.038 13.5 0.1 2.8 2 0 0 2 2 2 1 EF hand CH_2 PF06294.11 ORY90566.1 - 0.018 15.2 0.4 23 5.2 0.0 3.8 4 1 0 4 4 4 0 CH-like domain in sperm protein PIF PF05092.12 ORY90566.1 - 0.1 11.3 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 Per os infectivity Ribophorin_II PF05817.14 ORY90566.1 - 0.16 10.5 0.1 0.26 9.8 0.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Nramp PF01566.18 ORY90567.1 - 1.4e-108 363.0 21.3 1.4e-108 363.0 21.3 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein adh_short_C2 PF13561.6 ORY90568.1 - 3.9e-66 222.9 1.4 5.1e-66 222.6 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY90568.1 - 2.3e-52 177.3 2.2 2.8e-52 177.0 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY90568.1 - 1.6e-11 44.4 0.4 2.4e-11 43.8 0.4 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY90568.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY90568.1 - 0.0011 18.5 0.5 0.012 15.1 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHV-5_US34A PF17087.5 ORY90570.1 - 0.03 14.5 0.8 0.03 14.5 0.8 1.9 2 1 0 2 2 2 0 Herpesvirus US34A protein family Staphostatin_B PF09023.10 ORY90570.1 - 0.077 13.0 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Staphostatin B DUF4625 PF15418.6 ORY90571.1 - 0.0094 16.2 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) ADH_zinc_N PF00107.26 ORY90572.1 - 1.1e-24 86.8 0.0 1.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY90572.1 - 3.5e-18 67.0 0.0 5.8e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY90572.1 - 5.6e-12 45.5 0.1 1.4e-11 44.2 0.0 1.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MMR_HSR1_C PF08438.10 ORY90573.1 - 2.1e-37 128.1 0.7 4.1e-37 127.2 0.7 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ORY90573.1 - 4.4e-21 75.1 0.0 1.5e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY90573.1 - 3.3e-08 33.2 0.2 3.9e-07 29.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY90573.1 - 0.0015 18.6 1.5 0.0061 16.6 0.0 2.7 4 0 0 4 4 4 1 Dynamin family RsgA_GTPase PF03193.16 ORY90573.1 - 0.0076 16.2 0.2 1.2 9.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase TGS PF02824.21 ORY90573.1 - 0.023 14.7 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 TGS domain GTP_EFTU PF00009.27 ORY90573.1 - 0.045 13.3 1.1 0.32 10.5 0.7 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain HAD_2 PF13419.6 ORY90574.1 - 1.1e-10 41.8 0.0 1.4e-10 41.5 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY90574.1 - 2.7e-09 37.6 0.0 5.3e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY90574.1 - 2.9e-05 24.0 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Methyltransf_31 PF13847.6 ORY90574.1 - 0.2 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_2 PF07724.14 ORY90575.1 - 2.6e-55 187.2 0.0 3.1e-50 170.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORY90575.1 - 7.3e-34 115.8 0.6 7.3e-34 115.8 0.6 2.8 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 ORY90575.1 - 1.2e-27 96.9 0.9 1e-14 55.1 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY90575.1 - 1.1e-24 86.2 1.7 2.5e-24 85.1 0.1 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY90575.1 - 1.1e-18 67.6 0.1 2.7e-10 40.4 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 ORY90575.1 - 5.9e-18 64.7 0.0 8.2e-08 32.3 0.0 3.3 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 ORY90575.1 - 4.8e-12 46.6 6.3 5.2e-07 30.2 0.1 4.5 4 2 0 5 5 3 2 AAA ATPase domain Sigma54_activat PF00158.26 ORY90575.1 - 3.6e-11 43.1 0.1 2.6e-06 27.2 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORY90575.1 - 3.2e-08 33.5 0.1 0.0043 16.8 0.0 3.1 3 1 0 3 3 2 2 IstB-like ATP binding protein TniB PF05621.11 ORY90575.1 - 3.8e-08 33.0 0.0 0.00021 20.8 0.0 3.8 2 1 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 ORY90575.1 - 1.2e-07 32.1 2.2 0.022 15.0 0.0 4.2 3 2 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 ORY90575.1 - 7.4e-07 28.8 0.0 0.083 12.3 0.0 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORY90575.1 - 1.5e-06 28.3 0.1 0.051 13.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 ORY90575.1 - 2.5e-06 27.1 0.0 0.0049 16.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 ORY90575.1 - 1.4e-05 25.2 1.3 2.1 8.2 0.0 4.5 2 2 2 4 4 4 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 ORY90575.1 - 4.6e-05 24.0 3.4 0.064 13.8 0.0 3.5 3 1 0 3 3 2 2 AAA domain RuvB_N PF05496.12 ORY90575.1 - 6.9e-05 22.6 8.4 0.39 10.4 0.4 5.2 4 1 1 5 5 4 2 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 ORY90575.1 - 8.7e-05 22.5 0.0 0.023 14.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 ORY90575.1 - 0.00012 22.4 0.4 6.7 6.9 0.0 4.8 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 ORY90575.1 - 0.00015 22.0 0.0 0.39 10.9 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 ORY90575.1 - 0.00017 21.9 0.0 0.97 9.9 0.0 2.8 3 0 0 3 3 2 2 RNA helicase EzrA PF06160.12 ORY90575.1 - 0.00036 18.8 9.0 0.00064 18.0 9.0 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF815 PF05673.13 ORY90575.1 - 0.00077 18.7 5.3 0.041 13.1 0.5 3.9 3 2 0 3 3 3 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY90575.1 - 0.0013 18.5 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Torsin PF06309.11 ORY90575.1 - 0.0019 18.3 0.0 0.0085 16.2 0.0 2.1 2 0 0 2 2 1 1 Torsin ABC_tran PF00005.27 ORY90575.1 - 0.002 18.7 0.2 0.97 10.0 0.0 3.5 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 ORY90575.1 - 0.0021 18.0 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 ORY90575.1 - 0.0048 16.7 0.1 8 6.2 0.0 3.6 4 0 0 4 4 3 0 DNA polymerase III, delta subunit ResIII PF04851.15 ORY90575.1 - 0.0051 16.8 0.2 1 9.4 0.0 3.5 3 1 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 ORY90575.1 - 0.0083 16.0 0.0 2 8.3 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY90575.1 - 0.0089 16.2 0.0 12 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 ORY90575.1 - 0.0091 15.9 0.1 6 6.7 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase AAA_30 PF13604.6 ORY90575.1 - 0.017 14.8 0.0 3.3 7.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORY90575.1 - 0.022 14.5 0.0 4.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 ORY90575.1 - 0.023 14.4 0.4 4.7 6.8 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 ORY90575.1 - 0.036 14.6 13.2 0.5 10.8 0.6 4.3 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 ORY90575.1 - 0.041 14.2 0.4 1.1 9.6 0.1 3.3 3 1 0 3 3 2 0 AAA domain AAA_25 PF13481.6 ORY90575.1 - 0.05 13.2 2.5 1.2 8.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 ORY90575.1 - 0.084 12.8 0.1 17 5.3 0.0 3.4 3 0 0 3 3 3 0 NTPase ATP_bind_1 PF03029.17 ORY90575.1 - 0.11 12.3 0.0 2.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TIP49 PF06068.13 ORY90575.1 - 0.16 11.1 5.1 1.7 7.8 0.0 3.3 3 1 1 4 4 4 0 TIP49 P-loop domain Dynactin_p22 PF07426.11 ORY90575.1 - 0.23 11.3 9.8 3.9 7.3 2.5 3.3 2 1 1 3 3 3 0 Dynactin subunit p22 BLOC1_2 PF10046.9 ORY90575.1 - 0.53 10.6 9.6 0.069 13.4 3.6 2.5 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 ORY90575.1 - 0.66 9.3 5.9 1.2 8.4 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC92 PF14916.6 ORY90575.1 - 1.2 8.9 7.9 3.3 7.5 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil domain of unknown function AAA_17 PF13207.6 ORY90575.1 - 6 7.3 7.1 36 4.8 0.0 4.1 4 1 0 4 4 3 0 AAA domain Ssu72 PF04722.13 ORY90576.1 - 4.8e-85 283.9 0.0 5.4e-85 283.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein HMG_box PF00505.19 ORY90577.1 - 4.7e-19 68.6 11.0 4.3e-09 36.6 4.0 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY90577.1 - 5.4e-15 55.8 10.0 5.1e-07 30.2 1.2 2.6 2 0 0 2 2 2 2 HMG-box domain DUF3106 PF11304.8 ORY90577.1 - 0.015 15.7 6.0 0.89 10.1 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) COX4 PF02936.14 ORY90577.1 - 0.027 14.5 8.5 0.87 9.6 2.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Con-6 PF10346.9 ORY90577.1 - 0.042 13.9 0.4 8.9 6.4 0.1 2.8 2 0 0 2 2 2 0 Conidiation protein 6 PXA PF02194.15 ORY90578.1 - 1.1e-47 162.3 6.3 2.5e-46 157.9 3.1 2.8 3 0 0 3 3 3 2 PXA domain Nexin_C PF08628.12 ORY90578.1 - 3e-05 24.5 0.0 0.0001 22.8 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal Quaking_NLS PF16551.5 ORY90578.1 - 0.031 13.9 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking MASE2 PF05230.11 ORY90578.1 - 1.8 8.7 5.0 13 6.0 1.2 3.3 2 1 1 3 3 3 0 MASE2 domain MFS_1 PF07690.16 ORY90579.1 - 1.2e-47 162.5 21.3 1.2e-47 162.5 21.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY90579.1 - 3.1e-10 39.5 9.9 3.1e-10 39.5 9.9 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORY90579.1 - 7.6e-08 31.2 5.0 1.4e-07 30.3 5.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 ORY90579.1 - 0.002 17.1 0.2 0.006 15.5 0.1 1.8 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM OATP PF03137.20 ORY90579.1 - 0.0045 15.3 4.8 0.025 12.9 4.7 2.1 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3443 PF11925.8 ORY90580.1 - 0.033 13.0 0.9 0.052 12.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Apo-CIII PF05778.12 ORY90580.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) NUDIX PF00293.28 ORY90582.1 - 1.7e-29 102.5 0.0 2.4e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FAM70 PF14967.6 ORY90583.1 - 0.24 10.8 0.6 0.39 10.1 0.6 1.3 1 0 0 1 1 1 0 FAM70 protein IKI3 PF04762.12 ORY90584.1 - 1.1e-284 947.1 0.0 1.1e-284 947.1 0.0 1.4 2 0 0 2 2 2 1 IKI3 family Tom37 PF10568.9 ORY90584.1 - 0.0055 17.0 0.2 0.02 15.2 0.2 2.0 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein fn3_2 PF16893.5 ORY90584.1 - 0.16 12.1 0.4 0.76 10.0 0.1 2.3 2 0 0 2 2 2 0 Fibronectin type III domain Clathrin PF00637.20 ORY90584.1 - 0.18 11.7 6.9 7.7 6.4 0.2 3.0 1 1 1 2 2 2 0 Region in Clathrin and VPS Gmad1 PF10647.9 ORY90584.1 - 0.21 11.3 0.5 17 5.1 0.0 3.2 3 1 1 4 4 4 0 Lipoprotein LpqB beta-propeller domain FRB_dom PF08771.11 ORY90584.1 - 0.34 11.3 3.5 1 9.8 0.5 3.3 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Dishevelled PF02377.15 ORY90584.1 - 0.89 10.0 8.9 6.9 7.1 5.6 2.6 2 0 0 2 2 2 0 Dishevelled specific domain Ribosomal_L22 PF00237.19 ORY90587.1 - 1.8e-40 137.3 0.4 1.8e-40 137.3 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e ATP_synt_H PF05493.13 ORY90588.1 - 2.6e-21 75.8 5.8 3.1e-21 75.6 5.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H YibE_F PF07907.11 ORY90588.1 - 0.021 14.3 1.5 0.024 14.1 1.5 1.0 1 0 0 1 1 1 0 YibE/F-like protein DUF1129 PF06570.11 ORY90588.1 - 0.028 13.9 0.1 0.032 13.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2545 PF10810.8 ORY90588.1 - 0.046 13.9 2.5 0.059 13.5 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) Peptidase_U4 PF03419.13 ORY90588.1 - 0.075 12.3 1.5 0.077 12.3 1.5 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Phage_holin_5_2 PF16079.5 ORY90588.1 - 0.3 11.5 4.9 0.73 10.2 4.8 1.6 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V E1-E2_ATPase PF00122.20 ORY90588.1 - 0.71 9.4 2.2 0.8 9.2 2.2 1.0 1 0 0 1 1 1 0 E1-E2 ATPase MAGE PF01454.19 ORY90589.1 - 2e-48 164.9 0.0 2.8e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 MAGE family CLTH PF10607.9 ORY90590.1 - 5e-33 114.1 0.0 7e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY90590.1 - 6e-10 38.7 0.8 1.1e-09 37.9 0.1 1.8 2 0 0 2 2 2 1 LisH DUF3105 PF11303.8 ORY90590.1 - 0.08 13.1 0.0 6.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) AAA_33 PF13671.6 ORY90591.1 - 7.6e-05 22.9 0.0 8.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 ORY90591.1 - 0.00043 19.7 0.0 0.00043 19.7 0.0 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.10 ORY90591.1 - 0.0011 18.5 0.0 0.0013 18.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 ORY90591.1 - 0.0017 18.9 0.0 0.0017 18.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 ORY90591.1 - 0.003 17.5 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 ORY90591.1 - 0.0054 17.2 0.0 0.0061 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY90591.1 - 0.0083 16.4 0.1 0.01 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORY90591.1 - 0.0092 15.7 0.0 0.0093 15.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY90591.1 - 0.01 16.3 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 ORY90591.1 - 0.019 14.7 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ORY90591.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ORY90591.1 - 0.05 13.9 0.0 0.051 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY90591.1 - 0.052 13.9 0.1 0.052 13.9 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 ORY90591.1 - 0.056 13.5 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) VirE PF05272.11 ORY90591.1 - 0.056 13.2 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E MMR_HSR1 PF01926.23 ORY90591.1 - 0.061 13.4 0.0 0.068 13.2 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ORY90591.1 - 0.073 12.3 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 ORY90591.1 - 0.076 12.9 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 ORY90591.1 - 0.08 12.3 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI dNK PF01712.19 ORY90591.1 - 0.082 12.7 0.0 0.082 12.7 0.0 1.0 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_29 PF13555.6 ORY90591.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 ORY90591.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 ORY90591.1 - 0.12 12.8 0.1 0.12 12.8 0.1 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 ORY90591.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 ORY90591.1 - 0.2 10.6 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ADK PF00406.22 ORY90591.1 - 0.22 11.6 0.0 0.26 11.4 0.0 1.1 1 0 0 1 1 1 0 Adenylate kinase bZIP_1 PF00170.21 ORY90592.1 - 8.3e-09 35.4 15.0 3.1e-06 27.2 2.0 2.7 1 1 1 2 2 2 2 bZIP transcription factor Macoilin PF09726.9 ORY90592.1 - 7.1e-06 24.9 13.7 7.1e-06 24.9 13.7 1.8 2 0 0 2 2 2 1 Macoilin family bZIP_2 PF07716.15 ORY90592.1 - 0.00012 22.1 8.5 0.00012 22.1 8.5 3.6 3 1 1 4 4 4 2 Basic region leucine zipper YabA PF06156.13 ORY90592.1 - 0.0071 17.0 4.0 0.0071 17.0 4.0 3.3 3 0 0 3 3 3 1 Initiation control protein YabA XhlA PF10779.9 ORY90592.1 - 0.082 13.1 4.7 0.26 11.5 4.7 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Goodbye PF17109.5 ORY90592.1 - 0.094 13.2 0.3 0.094 13.2 0.3 3.0 3 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain SNAP PF14938.6 ORY90593.1 - 2.4e-08 33.8 0.3 3.5e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 ORY90593.1 - 0.17 12.6 0.0 0.17 12.6 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY90593.1 - 0.39 11.7 3.8 22 6.2 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CUE PF02845.16 ORY90594.1 - 3.8e-06 26.5 0.0 6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 ORY90594.1 - 0.0035 17.4 1.6 0.0065 16.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-associated protein 2 DUF4235 PF14019.6 ORY90594.1 - 0.78 9.9 7.2 0.11 12.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Ima1_N PF09779.9 ORY90595.1 - 3.5e-11 44.1 2.6 6e-11 43.3 2.6 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain zf-C4pol PF14260.6 ORY90595.1 - 0.12 12.8 4.5 34 5.0 4.5 2.3 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta BRCA-2_OB1 PF09103.10 ORY90596.1 - 2.5e-32 111.4 0.0 5.5e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 RGS PF00615.19 ORY90597.1 - 1.5e-30 105.8 0.0 4.2e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 ORY90597.1 - 2.2e-09 37.2 0.0 1.1e-05 25.4 0.0 2.7 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAC4 PF16093.5 ORY90597.1 - 0.12 12.6 1.6 0.95 9.7 0.0 3.1 3 1 0 3 3 3 0 Proteasome assembly chaperone 4 PAPA-1 PF04795.12 ORY90597.1 - 3.9 8.4 7.2 2 9.3 3.8 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region EF-hand_4 PF12763.7 ORY90598.1 - 2.3e-39 133.5 0.0 6.7e-15 54.9 0.0 3.8 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ORY90598.1 - 2.4e-07 31.1 0.0 5.7e-05 23.5 0.1 3.6 3 1 1 4 4 4 1 EF-hand domain pair UBA PF00627.31 ORY90598.1 - 1.2e-06 28.3 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 ORY90598.1 - 3.2e-06 26.3 0.7 0.84 9.3 0.1 4.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 ORY90598.1 - 0.0029 17.4 0.2 5.8 7.1 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 ORY90598.1 - 0.075 12.9 0.0 40 4.2 0.0 3.7 5 0 0 5 5 5 0 EF-hand domain pair hGDE_central PF14702.6 ORY90602.1 - 0.043 13.5 0.7 0.048 13.3 0.7 1.1 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme LMBR1 PF04791.16 ORY90602.1 - 0.2 10.5 2.7 0.24 10.3 2.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.25 ORY90958.1 - 1.7e-59 201.3 0.0 2.3e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90958.1 - 7.6e-23 81.1 0.0 1.1e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY90958.1 - 0.0013 18.1 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY90958.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORY90958.1 - 0.027 14.4 0.1 0.14 12.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY90958.1 - 0.24 10.7 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFO_IDH_MocA PF01408.22 ORY90959.1 - 1e-25 90.9 0.1 1.7e-25 90.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ORY90959.1 - 7.2e-06 26.5 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 ORY90959.1 - 2.3e-05 25.0 0.0 3.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ORY90959.1 - 0.0058 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY90959.1 - 0.048 13.7 0.0 0.087 12.9 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RNA_pol_L_2 PF13656.6 ORY90959.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain GP41 PF00517.17 ORY90962.1 - 0.037 13.9 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein F-box-like PF12937.7 ORY90963.1 - 6.1e-10 38.8 1.5 1.8e-09 37.4 1.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY90963.1 - 7e-05 22.6 0.1 0.00019 21.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain MSC PF09402.10 ORY90964.1 - 1.1e-45 156.6 2.2 1.2e-45 156.4 0.0 1.9 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ORY90964.1 - 6.6e-07 28.9 0.1 1.7e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain SKICH PF17751.1 ORY90964.1 - 0.12 13.0 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 SKICH domain DUF908 PF06012.12 ORY90964.1 - 0.7 9.2 4.4 1.1 8.6 4.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PPP4R2 PF09184.11 ORY90964.1 - 5.5 6.5 17.3 12 5.4 17.3 1.5 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 ORY90964.1 - 6.6 6.6 15.4 11 5.9 15.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nup54 PF13874.6 ORY90965.1 - 8.8e-35 119.8 4.2 8.8e-35 119.8 4.2 3.0 3 1 1 4 4 4 2 Nucleoporin complex subunit 54 TFIIA PF03153.13 ORY90965.1 - 0.69 9.9 29.9 3.1 7.7 30.1 1.9 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit SMC_N PF02463.19 ORY90967.1 - 6.6e-29 100.9 2.3 1.4e-28 99.8 2.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY90967.1 - 3.3e-12 46.8 10.8 3.3e-12 46.8 10.8 4.1 3 2 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 ORY90967.1 - 1.4e-05 25.1 0.1 0.0018 18.2 0.0 4.7 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY90967.1 - 1.5e-05 25.6 42.9 1.5e-05 25.6 42.9 6.5 3 2 2 5 5 5 1 AAA domain AAA_29 PF13555.6 ORY90967.1 - 4.7e-05 23.1 0.0 9.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 ORY90967.1 - 0.00046 20.5 0.0 0.003 17.9 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.6 ORY90967.1 - 0.0049 17.1 0.2 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 ORY90967.1 - 0.48 10.7 2.9 10 6.4 0.0 3.9 3 1 0 3 3 3 0 AAA domain Surfac_D-trimer PF09006.11 ORY90967.1 - 4.4 7.3 4.9 3.5 7.6 0.5 2.9 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF4203 PF13886.6 ORY90968.1 - 7.2e-32 110.7 31.2 8.4e-32 110.5 31.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) UCR_UQCRX_QCR9 PF05365.12 ORY90968.1 - 0.21 11.5 4.0 0.62 10.0 3.7 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like COX8 PF02285.15 ORY90968.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.8 4 0 0 4 4 4 0 Cytochrome oxidase c subunit VIII Chordopox_A13L PF05961.11 ORY90968.1 - 2.3 8.5 8.6 2.7 8.3 1.7 2.4 2 0 0 2 2 2 0 Chordopoxvirus A13L protein H_PPase PF03030.16 ORY90968.1 - 3.3 6.2 12.8 0.84 8.2 4.9 2.0 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase GPI-anchored PF10342.9 ORY90969.1 - 5.2e-12 46.4 0.1 9.9e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_7 PF17957.1 ORY90969.1 - 0.031 15.0 0.3 0.031 15.0 0.3 2.1 2 0 0 2 2 2 0 Bacterial Ig domain Yip1 PF04893.17 ORY90970.1 - 1.2e-08 34.9 15.5 2.4e-08 33.9 15.3 1.6 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 ORY90970.1 - 0.0058 16.2 14.4 0.27 10.7 14.4 2.3 1 1 0 1 1 1 1 YIF1 CAP_N PF01213.19 ORY90970.1 - 0.088 12.3 3.1 0.12 11.9 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_M16_M PF16187.5 ORY90971.1 - 7.9e-100 333.7 2.3 1.4e-99 332.9 2.3 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORY90971.1 - 3.8e-43 147.0 0.6 1.3e-41 142.0 0.1 3.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY90971.1 - 2.5e-36 125.4 0.1 4.7e-21 75.6 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Ribosomal_L37ae PF01780.19 ORY90972.1 - 1.5e-42 143.6 11.6 1.6e-42 143.4 11.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 ORY90972.1 - 0.00069 19.5 1.0 0.0011 19.0 1.0 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 ORY90972.1 - 0.0015 18.6 2.7 0.0015 18.6 2.7 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 ORY90972.1 - 0.017 15.2 1.0 0.024 14.6 1.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 ORY90972.1 - 0.096 12.4 3.0 6 6.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 ORY90972.1 - 0.12 12.3 3.3 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 ORY90972.1 - 0.15 12.4 2.1 1.5 9.2 2.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 ORY90972.1 - 0.32 11.1 5.1 1.2 9.2 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger HalOD2 PF18547.1 ORY90972.1 - 0.5 10.3 5.3 4 7.4 1.1 2.3 1 1 1 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 ORY90972.1 - 0.85 9.6 6.2 0.24 11.3 1.9 2.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 ORY90972.1 - 4.9 7.8 6.7 4.2 8.0 0.7 2.3 1 1 0 2 2 2 0 Zinc-finger double domain Gaa1 PF04114.14 ORY90973.1 - 2.1e-122 409.7 1.5 2.9e-122 409.3 1.5 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Methyltransf_25 PF13649.6 ORY90974.1 - 1.4e-18 67.4 0.0 2.3e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY90974.1 - 1.2e-14 54.7 0.0 2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY90974.1 - 3.1e-14 53.2 0.0 4.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY90974.1 - 1.2e-10 42.0 0.0 2.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY90974.1 - 6.8e-09 35.4 0.0 1.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.6 ORY90974.1 - 1.7e-08 34.4 0.0 8.6e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY90974.1 - 7.7e-07 28.7 0.0 1.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 ORY90974.1 - 0.0001 21.4 0.1 0.00022 20.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) MTS PF05175.14 ORY90974.1 - 0.0034 17.0 0.0 0.019 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 ORY90974.1 - 0.0046 15.6 0.1 0.017 13.7 0.1 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 ORY90974.1 - 0.007 15.7 0.0 0.051 12.9 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 ORY90974.1 - 0.03 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 ORY90974.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase FtsJ PF01728.19 ORY90974.1 - 0.06 13.5 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF938 PF06080.12 ORY90974.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) HPS3_N PF14761.6 ORY90974.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 DUF3176 PF11374.8 ORY90975.1 - 0.021 15.0 0.1 0.049 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) DUF3176 PF11374.8 ORY90976.1 - 5.5e-12 45.8 5.5 6.6e-11 42.4 0.7 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3176) Phage_gp53 PF11246.8 ORY90976.1 - 0.05 13.3 0.3 0.097 12.3 0.3 1.4 1 0 0 1 1 1 0 Base plate wedge protein 53 Coq4 PF05019.13 ORY90976.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GxDLY PF14607.6 ORY90977.1 - 0.055 13.3 0.3 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type SH PF01445.17 ORY90978.1 - 0.054 13.5 1.1 0.059 13.3 1.1 1.1 1 0 0 1 1 1 0 Viral small hydrophobic protein CHCH PF06747.13 ORY90980.1 - 2.1e-05 24.5 0.8 3.1e-05 24.0 0.8 1.3 1 0 0 1 1 1 1 CHCH domain Prok-TraM PF09228.10 ORY90980.1 - 0.09 13.2 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Xan_ur_permease PF00860.20 ORY90981.1 - 4.6e-29 101.3 29.3 7.3e-28 97.4 27.7 2.5 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 ORY90981.1 - 0.00058 20.2 2.6 0.00058 20.2 2.6 2.9 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily TERB2 PF15101.6 ORY90981.1 - 0.055 13.5 1.8 0.086 12.9 1.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4355 PF14265.6 ORY90982.1 - 0.062 13.6 10.8 0.069 13.4 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TFIIA PF03153.13 ORY90982.1 - 0.66 9.9 22.3 0.72 9.8 22.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 ORY90982.1 - 0.7 9.9 7.4 0.8 9.7 7.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 ORY90982.1 - 0.82 8.6 11.2 0.8 8.6 11.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 ORY90982.1 - 1.8 8.7 8.1 2.1 8.5 8.1 1.1 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 ORY90982.1 - 2 7.9 27.5 2.6 7.6 27.5 1.1 1 0 0 1 1 1 0 Spt20 family Sec62 PF03839.16 ORY90982.1 - 2.5 7.6 9.1 2.9 7.3 9.1 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3043 PF11241.8 ORY90982.1 - 6.5 6.8 8.3 8.3 6.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TERB2 PF15101.6 ORY90982.1 - 6.9 6.7 10.8 8 6.5 10.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 ORY90982.1 - 8.1 5.1 12.4 8.2 5.1 12.4 1.0 1 0 0 1 1 1 0 Presenilin PBP1_TM PF14812.6 ORY90983.1 - 0.36 11.2 10.2 0.55 10.6 10.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LYRIC PF15686.5 ORY90983.1 - 1.3 8.5 6.1 1.5 8.3 6.1 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family MFMR_assoc PF16596.5 ORY90983.1 - 2 8.9 10.7 2.7 8.5 10.7 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR CCDC106 PF15794.5 ORY90983.1 - 7.5 6.2 7.0 9.6 5.8 7.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 D123 PF07065.14 ORY90984.1 - 4e-93 311.9 5.6 4.9e-93 311.6 5.6 1.1 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 ORY90984.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Usg PF06233.12 ORY90984.1 - 0.87 9.8 3.5 17 5.6 0.0 3.0 3 0 0 3 3 3 0 Usg-like family SPC12 PF06645.13 ORY90985.1 - 4.1e-29 100.5 0.3 4.8e-29 100.3 0.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Enterotoxin_HS1 PF08090.11 ORY90986.1 - 0.012 15.6 2.3 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 HTH_Tnp_ISL3 PF13542.6 ORY90986.1 - 0.055 12.9 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 p450 PF00067.22 ORY90987.1 - 4.7e-84 282.8 0.0 5.9e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EPL1 PF10513.9 ORY90988.1 - 3e-19 70.0 0.7 7.6e-19 68.6 0.7 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like Rtt106 PF08512.12 ORY90989.1 - 6.8e-26 90.5 0.0 2e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like POB3_N PF17292.2 ORY90989.1 - 1.9e-25 89.1 0.2 3.8e-23 81.7 0.1 2.7 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 ORY90989.1 - 8.9e-21 73.6 0.2 4e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Creatinase_N PF01321.18 ORY90989.1 - 0.058 14.1 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Acetyltransf_11 PF13720.6 ORY90989.1 - 0.063 13.7 0.0 0.33 11.5 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PDZ_2 PF13180.6 ORY90989.1 - 0.082 13.2 0.5 0.93 9.9 0.1 2.5 2 1 0 2 2 2 0 PDZ domain Glyco_transf_11 PF01531.16 ORY90990.1 - 8.4e-05 21.9 1.7 0.23 10.6 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 11 SseB_C PF14581.6 ORY90990.1 - 0.015 15.3 0.2 0.39 10.8 0.0 2.7 3 0 0 3 3 3 0 SseB protein C-terminal domain C5-epim_C PF06662.13 ORY90990.1 - 0.13 11.7 0.1 26 4.3 0.0 3.0 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus RhoGEF PF00621.20 ORY90992.1 - 7.7e-31 107.7 0.1 1.2e-30 107.1 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 ORY90992.1 - 1.6e-06 28.6 0.0 2.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 ORY90992.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Uds1 PF15456.6 ORY90992.1 - 0.057 13.6 4.0 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Up-regulated During Septation Rootletin PF15035.6 ORY90992.1 - 0.16 11.9 0.5 1.9 8.4 0.1 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Zn_clus PF00172.18 ORY90994.1 - 2.3e-05 24.4 16.1 5.3e-05 23.2 16.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 ORY90994.1 - 0.017 14.7 12.4 0.024 14.2 4.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 ORY90994.1 - 0.17 10.4 3.6 0.21 10.1 3.6 1.2 1 0 0 1 1 1 0 Macoilin family Med3 PF11593.8 ORY90994.1 - 0.91 8.6 17.9 0.19 10.9 4.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Glyco_hydro_9 PF00759.19 ORY90995.1 - 6.7e-116 388.1 16.1 7.8e-116 387.9 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 MSP7_C PF12948.7 ORY90995.1 - 0.012 16.3 0.0 0.035 14.8 0.0 1.7 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Glyco_hydro_88 PF07470.13 ORY90995.1 - 0.016 14.3 0.6 0.033 13.3 0.4 1.5 1 1 0 1 1 1 0 Glycosyl Hydrolase Family 88 BCNT PF07572.12 ORY90996.1 - 1e-20 73.5 0.8 1e-20 73.5 0.8 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development Hamartin PF04388.12 ORY90996.1 - 4.3 5.9 14.0 5.1 5.6 14.0 1.1 1 0 0 1 1 1 0 Hamartin protein Tim17 PF02466.19 ORY90997.1 - 8.7e-37 125.9 8.6 1.3e-36 125.3 8.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FG-GAP_2 PF14312.6 ORY90997.1 - 0.032 14.5 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 FG-GAP repeat A_deaminase PF00962.22 ORY90998.1 - 1.1e-25 90.7 0.0 1.3e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Aminotran_4 PF01063.19 ORY90999.1 - 2.4e-29 102.8 0.0 2.9e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV zf-BED PF02892.15 ORY91001.1 - 8.9e-07 28.8 0.4 2.6e-06 27.4 0.4 1.8 1 0 0 1 1 1 1 BED zinc finger RRM_1 PF00076.22 ORY91002.1 - 4e-11 42.6 0.0 8.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY91002.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CNDH2_C PF16858.5 ORY91002.1 - 0.26 11.1 29.6 27 4.5 0.0 2.1 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term GRIM-19 PF06212.12 ORY91003.1 - 1.5e-34 118.8 0.0 1.7e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Chitin_synth_1 PF01644.17 ORY91004.1 - 4.9e-79 264.0 0.0 7.7e-79 263.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY91004.1 - 1.4e-30 105.1 0.3 6.1e-30 103.0 0.3 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY91004.1 - 1.1e-22 80.4 1.6 3.2e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY91004.1 - 0.00018 21.5 15.8 0.0068 16.3 16.2 3.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY91004.1 - 0.027 14.4 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 GYR PF02756.14 ORY91004.1 - 0.77 9.5 5.7 1.6 8.5 5.7 1.5 1 0 0 1 1 1 0 GYR motif Lon_C PF05362.13 ORY91005.1 - 7.5e-71 237.9 0.0 1.5e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORY91005.1 - 9.9e-35 120.3 1.1 2e-34 119.3 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORY91005.1 - 8.8e-23 81.2 0.0 2.1e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY91005.1 - 1.5e-06 28.2 0.0 3.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY91005.1 - 3.2e-06 27.4 0.0 8.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 ORY91005.1 - 1.5e-05 24.9 0.0 3.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 ORY91005.1 - 2.9e-05 23.2 0.0 6.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 ORY91005.1 - 5.2e-05 23.0 0.0 0.00034 20.4 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY91005.1 - 0.00032 21.0 0.1 0.0036 17.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY91005.1 - 0.00075 19.9 0.5 0.0033 17.8 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY91005.1 - 0.0009 19.8 0.5 0.026 15.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 ORY91005.1 - 0.0062 16.6 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORY91005.1 - 0.0098 15.8 0.8 0.29 11.0 0.0 3.0 2 1 1 3 3 3 1 NTPase AAA_3 PF07726.11 ORY91005.1 - 0.014 15.3 0.0 0.083 12.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY91005.1 - 0.018 14.7 0.0 0.085 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY91005.1 - 0.041 13.6 0.1 2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY91005.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 ORY91005.1 - 0.068 13.3 0.1 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.17 ORY91005.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Phage_connect_1 PF05135.13 ORY91005.1 - 0.1 13.1 0.5 0.37 11.3 0.1 2.2 2 0 0 2 2 1 0 Phage gp6-like head-tail connector protein Pyridoxal_deC PF00282.19 ORY91005.1 - 0.17 10.5 0.1 0.28 9.8 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DNTTIP1_dimer PF18192.1 ORY91005.1 - 0.86 10.0 4.5 7.8 6.9 0.2 3.6 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain ClpB_D2-small PF10431.9 ORY91005.1 - 0.94 9.6 5.2 0.61 10.2 0.2 2.9 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein Mito_carr PF00153.27 ORY91006.1 - 5.7e-42 141.6 1.9 1.5e-21 76.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2574 PF10836.8 ORY91006.1 - 0.047 13.6 0.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) GRP PF07172.11 ORY91007.1 - 1.4e-08 35.3 53.7 2.9e-08 34.3 26.5 2.3 2 0 0 2 2 2 2 Glycine rich protein family Keratin_2_tail PF16210.5 ORY91007.1 - 4.8 7.4 40.7 0.57 10.5 27.2 2.2 2 0 0 2 2 2 0 Keratin type II cytoskeletal 1 tail Pro_isomerase PF00160.21 ORY91009.1 - 3.9e-43 147.4 0.0 6.2e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORY91009.1 - 1.3e-16 60.2 0.0 2.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ac110_PIF PF07280.11 ORY91010.1 - 0.068 13.0 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Per os infectivity factor AC110 Usp PF00582.26 ORY91011.1 - 4.2e-26 92.1 0.1 6.5e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family AA_permease_2 PF13520.6 ORY91012.1 - 3.6e-63 213.9 48.4 4.3e-63 213.6 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY91012.1 - 5.5e-34 117.6 36.4 7.6e-34 117.1 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease Metallophos PF00149.28 ORY91013.1 - 2.3e-13 51.1 0.4 3.2e-13 50.7 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 ORY91015.1 - 9.1e-09 35.1 0.9 1.5e-08 34.4 0.9 1.4 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 ORY91015.1 - 1.7e-05 24.6 1.3 0.021 14.9 1.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY91015.1 - 0.00096 18.9 0.9 0.1 12.4 1.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY91015.1 - 0.0016 18.5 0.4 0.0042 17.2 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.33 ORY91015.1 - 0.0038 17.1 0.5 0.011 15.6 0.5 1.8 1 1 0 1 1 1 1 F-box domain TPR_12 PF13424.6 ORY91015.1 - 0.0083 16.4 2.9 0.057 13.7 1.8 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat DXP_synthase_N PF13292.6 ORY91015.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TPR_14 PF13428.6 ORY91015.1 - 0.21 12.5 4.4 2.1 9.4 3.6 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_L32p PF01783.23 ORY91016.1 - 1.1e-16 60.9 6.8 1.5e-16 60.4 6.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF3797 PF12677.7 ORY91016.1 - 0.027 14.3 1.0 0.043 13.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.6 ORY91016.1 - 0.8 9.2 5.0 2 8.0 5.0 1.6 1 1 0 1 1 1 0 zinc-ribbon domain IF-2B PF01008.17 ORY91017.1 - 9.1e-82 274.4 0.0 1.4e-81 273.8 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family SOBP PF15279.6 ORY91017.1 - 0.2 12.2 14.8 0.29 11.7 14.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 ORY91017.1 - 0.57 8.8 10.5 0.73 8.4 10.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 ORY91017.1 - 0.94 6.5 11.4 1.1 6.3 11.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCSAP PF15748.5 ORY91017.1 - 4.1 7.5 26.1 6.1 6.9 26.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 ORY91017.1 - 5 5.8 18.2 7.8 5.1 18.2 1.3 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 ORY91019.1 - 3.9 5.5 6.5 6 4.8 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Aquarius_N PF16399.5 ORY91020.1 - 1.5e-286 952.6 3.7 1.9e-286 952.3 3.7 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 ORY91020.1 - 9.9e-31 107.5 0.0 4.1e-30 105.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORY91020.1 - 1.5e-25 90.0 0.0 3.2e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY91020.1 - 1.5e-11 44.9 0.0 4.9e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY91020.1 - 1.1e-09 38.3 0.0 0.00061 19.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ORY91020.1 - 0.0001 22.1 0.0 0.48 10.1 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 ORY91020.1 - 0.00016 21.7 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 ORY91020.1 - 0.00026 20.8 0.2 0.00066 19.4 0.2 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 ORY91020.1 - 0.00037 20.1 0.0 0.00086 18.9 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 ORY91020.1 - 0.00059 19.6 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 ORY91020.1 - 0.0055 16.0 1.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 ORY91020.1 - 0.019 15.2 0.0 0.1 12.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY91020.1 - 0.035 13.7 0.1 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 ORY91020.1 - 0.038 13.5 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 ORY91020.1 - 0.043 13.3 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 ORY91020.1 - 0.044 14.2 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain RAC_head PF16717.5 ORY91020.1 - 0.046 14.7 0.8 14 6.7 1.0 3.0 2 0 0 2 2 2 0 Ribosome-associated complex head domain AAA PF00004.29 ORY91020.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY91020.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIID-18kDa PF02269.16 ORY91021.1 - 7.3e-27 93.2 0.2 1.2e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF2722 PF10846.8 ORY91021.1 - 0.0001 21.4 4.5 0.0001 21.4 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 ORY91021.1 - 0.018 15.1 18.8 0.019 15.0 18.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TT_ORF2 PF02957.15 ORY91021.1 - 0.06 14.3 3.2 0.094 13.6 3.2 1.3 1 0 0 1 1 1 0 TT viral ORF2 CCDC53 PF10152.9 ORY91021.1 - 0.099 13.1 7.9 0.13 12.6 7.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 ORY91021.1 - 0.1 11.3 2.3 0.094 11.4 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.13 ORY91021.1 - 0.31 11.7 15.0 0.44 11.2 15.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 ORY91021.1 - 0.39 9.4 1.5 0.47 9.2 1.5 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 ORY91021.1 - 0.56 9.8 26.7 0.79 9.3 26.7 1.2 1 0 0 1 1 1 0 Spt20 family PepSY_TM PF03929.16 ORY91021.1 - 0.77 9.4 3.8 0.91 9.1 3.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF1180 PF06679.12 ORY91021.1 - 0.81 10.1 3.3 1.1 9.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4834 PF16118.5 ORY91021.1 - 1.2 10.1 8.1 0.24 12.4 4.8 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 ORY91021.1 - 1.7 8.5 9.8 2.1 8.2 9.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex2_Pex12 PF04757.14 ORY91022.1 - 1.6e-34 119.5 8.4 2.1e-34 119.1 8.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 ORY91022.1 - 0.00072 19.5 5.6 0.0014 18.5 5.6 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY91022.1 - 0.0035 17.2 1.9 0.017 14.9 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY91022.1 - 0.0055 16.8 4.4 0.0055 16.8 4.4 1.8 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY91022.1 - 0.0062 16.4 5.8 0.011 15.6 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY91022.1 - 0.008 16.2 4.7 0.016 15.2 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY91022.1 - 0.082 12.8 5.4 0.3 11.0 5.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY91022.1 - 0.26 11.6 4.2 0.48 10.7 4.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY91022.1 - 0.29 11.0 2.3 2.6 8.0 1.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY91022.1 - 0.34 11.3 6.4 0.91 9.9 6.4 1.8 1 1 0 1 1 1 0 Ring finger domain UCR_hinge PF02320.16 ORY91023.1 - 7.2e-23 80.6 9.8 7.2e-23 80.6 9.8 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DUF2052 PF09747.9 ORY91023.1 - 0.22 11.6 7.6 0.26 11.4 7.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pilin_PilA PF14245.6 ORY91026.1 - 0.002 18.1 0.1 0.0025 17.8 0.1 1.2 1 0 0 1 1 1 1 Type IV pilin PilA DDE_3 PF13358.6 ORY91027.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease PqqD PF05402.12 ORY91027.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) NMD3 PF04981.13 ORY91028.1 - 0.0071 15.8 0.7 0.0079 15.7 0.7 1.0 1 0 0 1 1 1 1 NMD3 family GST_C_3 PF14497.6 ORY91033.1 - 3e-16 59.4 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY91033.1 - 0.017 15.3 0.0 0.05 13.8 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY91033.1 - 0.033 14.5 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY91033.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORY91033.1 - 0.11 12.3 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2408 PF10303.9 ORY91034.1 - 7.9e-47 159.2 0.8 2e-24 86.7 0.0 4.7 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Med30 PF11315.8 ORY91034.1 - 4.2 7.6 6.5 2.3 8.4 0.1 3.1 4 0 0 4 4 4 0 Mediator complex subunit 30 Pkinase PF00069.25 ORY91035.1 - 4e-25 88.7 0.0 4.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91035.1 - 9.8e-14 51.3 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY91035.1 - 1.3e-07 30.8 0.0 1.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY91035.1 - 0.081 12.8 0.0 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 ORY91036.1 - 2.4e-38 129.4 18.5 9.4e-07 29.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY91036.1 - 1.6e-21 76.4 2.9 0.0011 19.2 0.0 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY91036.1 - 1.6e-08 34.7 0.1 0.00076 19.4 0.0 3.6 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY91036.1 - 1.7e-06 27.6 0.1 2.8e-05 23.6 0.0 2.5 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 ORY91036.1 - 3.4e-06 26.3 1.9 1.7 7.5 0.0 4.7 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY91036.1 - 6.3e-06 25.0 0.5 7.3e-05 21.5 0.1 2.5 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 ORY91036.1 - 0.00013 20.7 5.0 0.027 13.1 0.1 2.9 3 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ PF01011.21 ORY91036.1 - 0.00017 21.3 0.3 0.016 15.1 0.0 3.1 3 0 0 3 3 3 1 PQQ enzyme repeat DUF3748 PF12566.8 ORY91036.1 - 0.0057 16.6 0.0 0.32 11.0 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3748) Hira PF07569.11 ORY91036.1 - 0.027 14.2 0.0 1.8 8.3 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split PQQ_3 PF13570.6 ORY91036.1 - 0.046 14.2 0.3 88 3.8 0.0 4.1 4 0 0 4 4 3 0 PQQ-like domain VID27 PF08553.10 ORY91036.1 - 0.081 12.0 0.7 0.26 10.3 0.1 2.0 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain Big_3_5 PF16640.5 ORY91036.1 - 0.14 12.3 0.5 5.9 7.2 0.1 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Lip_prot_lig_C PF10437.9 ORY91037.1 - 5e-10 39.2 0.0 2.6e-09 36.9 0.0 2.2 3 0 0 3 3 3 1 Bacterial lipoate protein ligase C-terminus CO_deh_flav_C PF03450.17 ORY91037.1 - 0.0047 17.1 0.1 0.0095 16.1 0.1 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain BPL_LplA_LipB PF03099.19 ORY91037.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Peptidase_M22 PF00814.25 ORY91037.1 - 0.1 12.3 0.0 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycoprotease family IMUP PF15761.5 ORY91038.1 - 0.21 12.3 3.8 0.28 11.9 3.8 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 ORY91038.1 - 2 8.0 8.0 2.5 7.7 8.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 ORY91038.1 - 2.1 8.6 9.9 3.1 8.1 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pro_Al_protease PF02983.14 ORY91039.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-lytic protease prodomain ACP_syn_III_C PF08541.10 ORY91039.1 - 0.2 11.8 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NTP_transferase PF00483.23 ORY91041.1 - 1.5e-53 182.0 0.0 2.3e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORY91041.1 - 1.3e-12 46.9 8.5 3.4e-10 39.2 3.1 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY91041.1 - 4.9e-10 40.0 0.0 7.3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY91041.1 - 2.1e-05 24.1 1.6 2.1e-05 24.1 1.6 3.2 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORY91041.1 - 0.014 13.5 0.1 0.021 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 ORY91041.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Sad1_UNC PF07738.13 ORY91043.1 - 3.8e-08 33.4 0.0 4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ANAPC10 PF03256.16 ORY91043.1 - 0.071 12.7 0.0 0.076 12.6 0.0 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) DUF4457 PF14652.6 ORY91043.1 - 0.19 10.9 0.0 0.2 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) Transglut_core PF01841.19 ORY91045.1 - 3e-13 50.2 0.3 5.9e-13 49.3 0.3 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 ORY91045.1 - 1.6e-10 40.9 0.8 3.2e-10 39.9 0.8 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Pyrid_ox_like PF16242.5 ORY91046.1 - 0.00089 18.9 0.0 0.043 13.4 0.0 2.4 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase like Sin3a_C PF16879.5 ORY91047.1 - 2.5e-63 214.5 7.1 9.3e-63 212.6 5.9 2.5 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY91047.1 - 2.7e-44 149.0 10.4 1.2e-18 67.0 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY91047.1 - 4.4e-40 135.7 0.6 1.8e-39 133.8 0.6 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor RR_TM4-6 PF06459.12 ORY91047.1 - 3.5 7.4 9.2 8.1 6.2 9.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HMG_box PF00505.19 ORY91048.1 - 5.4e-15 55.6 4.7 5.4e-15 55.6 4.7 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY91048.1 - 2.7e-10 40.7 3.8 2.7e-10 40.7 3.8 2.8 3 0 0 3 3 3 1 HMG-box domain DUF3439 PF11921.8 ORY91048.1 - 0.015 15.3 4.5 0.028 14.4 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zn-ribbon_14 PF16503.5 ORY91049.1 - 3.8e-18 64.7 5.0 3.8e-18 64.7 5.0 3.3 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 ORY91049.1 - 1.3e-17 64.2 0.0 2.2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 ORY91049.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DZR PF12773.7 ORY91049.1 - 7.6 6.6 9.9 2.5 8.2 0.1 3.0 3 0 0 3 3 3 0 Double zinc ribbon Suv3_C_1 PF18147.1 ORY91050.1 - 4e-14 52.2 0.2 1e-13 50.9 0.2 1.8 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 ORY91050.1 - 2.3e-11 44.0 0.0 4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 ORY91050.1 - 0.012 15.5 0.5 0.012 15.5 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal VPS13_C PF16909.5 ORY91051.1 - 0.0052 16.6 0.2 0.0057 16.4 0.2 1.0 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal CD99L2 PF12301.8 ORY91051.1 - 0.92 9.8 3.0 1.2 9.5 3.0 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 RTX PF02382.15 ORY91051.1 - 1.9 8.1 5.1 2.2 7.9 5.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein SseC PF04888.12 ORY91051.1 - 2.4 7.7 7.9 2.7 7.5 7.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Arrestin_C PF02752.22 ORY91052.1 - 9.5e-18 64.9 0.3 2.8e-15 56.9 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY91052.1 - 4.3e-05 23.6 0.0 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY91052.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.5 1 1 0 1 1 1 1 Arrestin_N terminal like FAT PF02259.23 ORY91053.1 - 1.8e-73 247.8 7.9 1.8e-73 247.8 7.9 2.5 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORY91053.1 - 2.9e-27 96.1 0.5 1.1e-26 94.2 0.2 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 ORY91053.1 - 9.9e-06 25.3 0.3 2.5e-05 24.0 0.3 1.7 1 0 0 1 1 1 1 FATC domain DUF1160 PF06648.11 ORY91053.1 - 0.013 15.5 0.2 0.064 13.2 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) RasGEF_N_2 PF14663.6 ORY91053.1 - 0.15 12.5 1.2 1 9.8 0.1 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIX1 PF08167.12 ORY91053.1 - 0.22 11.2 3.1 13 5.5 0.0 5.0 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 ORY91053.1 - 0.35 10.8 4.7 3.7 7.4 0.0 4.8 4 1 0 5 5 5 0 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 ORY91053.1 - 9 4.7 18.6 0.37 9.3 0.6 4.7 5 0 0 5 5 5 0 Adaptin N terminal region PIP5K PF01504.18 ORY91054.1 - 4e-41 141.1 5.4 2.4e-33 115.5 0.2 2.7 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Ribosomal_L39 PF00832.20 ORY91055.1 - 9.1e-19 66.8 13.8 9.1e-19 66.8 13.8 1.4 2 0 0 2 2 2 1 Ribosomal L39 protein Atg8 PF02991.16 ORY91056.1 - 4.9e-52 174.5 0.2 5.8e-52 174.2 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ORY91056.1 - 3.3e-07 30.6 0.0 4.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 XPG_I PF00867.18 ORY91057.1 - 1.7e-16 60.3 0.0 3.6e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY91057.1 - 0.0011 19.4 0.0 0.0044 17.5 0.0 2.0 2 1 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 ORY91057.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 XPG domain containing Ribosomal_S19e PF01090.19 ORY91058.1 - 1.7e-59 199.4 0.1 1.9e-59 199.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Thiolase_N PF00108.23 ORY91059.1 - 5.4e-19 68.6 0.2 7.6e-18 64.8 0.1 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY91059.1 - 6.2e-11 42.0 0.0 3e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 ORY91059.1 - 0.00013 22.0 0.1 0.065 13.3 0.0 3.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 ORY91059.1 - 0.00097 18.8 4.1 0.12 12.0 0.6 2.5 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY91059.1 - 0.0086 15.9 0.8 0.64 9.9 0.2 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 ORY91059.1 - 0.012 14.3 0.1 0.65 8.7 0.1 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Plasmo_rep PF12135.8 ORY91059.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Plasmodium repeat family DPBB_1 PF03330.18 ORY91061.1 - 7.6e-11 42.1 0.1 1.2e-10 41.5 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY91061.1 - 0.0029 17.5 0.3 0.0032 17.3 0.3 1.2 1 0 0 1 1 1 1 Barwin family DHQ_synthase PF01761.20 ORY91062.1 - 1.2e-95 319.7 0.0 1.8e-95 319.0 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 ORY91062.1 - 3.2e-41 142.1 0.0 1e-40 140.4 0.0 1.8 3 0 0 3 3 3 1 Type I 3-dehydroquinase Fe-ADH_2 PF13685.6 ORY91062.1 - 2.6e-07 30.6 0.5 1.1e-06 28.5 0.5 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 ORY91062.1 - 0.00013 20.9 3.4 0.00083 18.3 1.6 2.6 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase dCache_3 PF14827.6 ORY91062.1 - 0.056 13.1 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Ank_4 PF13637.6 ORY91063.1 - 4.8e-12 46.2 0.4 9.5e-06 26.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY91063.1 - 8.2e-10 39.1 1.9 2.1e-08 34.6 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY91063.1 - 1.3e-09 38.1 1.2 1.8e-05 24.9 0.4 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY91063.1 - 1.2e-07 31.4 0.0 0.023 15.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY91063.1 - 2.8e-07 30.7 1.2 0.0037 17.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat RasGEF PF00617.19 ORY91064.1 - 1.1e-59 201.7 0.2 2.2e-59 200.6 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY91064.1 - 5.5e-25 87.6 3.1 8.8e-25 87.0 0.8 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif WW PF00397.26 ORY91064.1 - 3.1e-15 55.9 3.2 1.9e-07 31.0 0.7 2.9 2 0 0 2 2 2 2 WW domain SH3_1 PF00018.28 ORY91064.1 - 5.2e-12 45.2 0.3 1.1e-11 44.1 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY91064.1 - 1.1e-09 37.9 0.0 2.2e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY91064.1 - 4e-09 36.2 0.2 1.3e-08 34.6 0.2 2.0 1 0 0 1 1 1 1 Variant SH3 domain BORCS8 PF10167.9 ORY91064.1 - 0.00096 19.1 1.9 0.0013 18.7 0.0 2.2 3 0 0 3 3 3 1 BLOC-1-related complex sub-unit 8 DUF4973 PF16343.5 ORY91064.1 - 0.057 13.5 1.3 0.1 12.6 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4973) PDZ_5 PF17817.1 ORY91065.1 - 0.11 12.9 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 PDZ domain IGR PF09597.10 ORY91066.1 - 3.1e-25 88.0 0.1 4e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 IGR protein motif Rieske PF00355.26 ORY91067.1 - 6.1e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Med19 PF10278.9 ORY91067.1 - 1.9 8.4 14.3 3.9 7.4 14.3 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_C12 PF01088.21 ORY91068.1 - 1.5e-70 237.2 0.0 2.4e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ORY91068.1 - 1.7e-16 59.8 6.1 3.2e-16 59.0 6.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DUF4203 PF13886.6 ORY91069.1 - 2.6e-37 128.4 31.0 3.8e-37 127.9 31.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF1206 PF06724.11 ORY91070.1 - 1.9e-24 85.5 18.9 2.4e-14 53.1 2.0 3.1 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) Abhydrolase_9_N PF15420.6 ORY91070.1 - 0.038 14.0 0.9 0.038 14.0 0.9 1.7 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus BSP_II PF05432.11 ORY91070.1 - 0.093 12.4 4.7 0.051 13.3 2.7 1.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4271 PF14093.6 ORY91070.1 - 0.26 11.2 4.9 0.85 9.5 2.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) DUF4770 PF15994.5 ORY91070.1 - 0.39 10.9 1.3 0.69 10.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF2061 PF09834.9 ORY91070.1 - 0.75 10.4 4.1 5.5 7.6 1.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) DUF4064 PF13273.6 ORY91070.1 - 8.5 6.7 12.0 5.2 7.4 2.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Shugoshin_N PF07558.11 ORY91071.1 - 6.9e-08 32.2 3.9 1.3e-07 31.4 3.9 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 ORY91071.1 - 0.039 13.8 0.4 0.13 12.1 0.4 1.9 1 0 0 1 1 1 0 Shugoshin C terminus Trypan_PARP PF05887.11 ORY91071.1 - 1.7 8.6 25.7 6.7 6.7 25.7 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L24e PF01246.20 ORY91072.1 - 5.3e-31 106.6 6.3 5.3e-31 106.6 6.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e CDC24_OB3 PF17244.2 ORY91073.1 - 9.7e-47 159.5 0.0 3.3e-46 157.8 0.0 1.8 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB1 PF17246.2 ORY91073.1 - 3.8e-13 49.6 0.0 7.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 tRNA_anti-codon PF01336.25 ORY91073.1 - 0.00013 21.9 0.1 0.0009 19.2 0.1 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 ORY91073.1 - 0.039 13.9 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Replication protein A OB domain GPI-anchored PF10342.9 ORY91074.1 - 3.1e-05 24.6 1.0 3.1e-05 24.6 1.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.25 ORY91075.1 - 2.3e-66 223.8 0.2 5.2e-66 222.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91075.1 - 2.1e-39 135.4 0.0 3.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY91075.1 - 3e-06 26.8 0.0 2.7e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 ORY91075.1 - 0.0059 16.6 1.5 3.2 7.6 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY91075.1 - 0.015 14.2 0.0 0.015 14.2 0.0 2.5 3 0 0 3 3 3 0 Haspin like kinase domain RIO1 PF01163.22 ORY91075.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.7 3 1 1 4 4 4 0 RIO1 family dsRBD2 PF17842.1 ORY91075.1 - 1.3 9.2 9.7 0.41 10.9 1.9 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 DUF1764 PF08576.10 ORY91075.1 - 3.6 8.6 13.8 0.11 13.4 1.3 3.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) Itfg2 PF15907.5 ORY91075.1 - 8.5 5.3 11.1 0.51 9.3 1.6 2.8 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 Hydrolase PF00702.26 ORY91076.1 - 4.4e-08 33.7 0.0 7.8e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY91076.1 - 0.003 17.7 0.0 0.0043 17.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY91076.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like PQQ PF01011.21 ORY91077.1 - 9.9e-13 47.4 2.0 0.019 14.9 0.1 4.5 4 0 0 4 4 4 4 PQQ enzyme repeat PQQ_2 PF13360.6 ORY91077.1 - 1e-12 48.2 0.3 2.4e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 PQQ-like domain zf-HC5HC2H_2 PF13832.6 ORY91078.1 - 5.5e-13 49.0 19.7 1.8e-12 47.4 12.6 2.9 2 1 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 ORY91078.1 - 1.8e-12 46.6 3.8 1.8e-12 46.6 3.8 2.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 ORY91078.1 - 4.6e-11 42.8 7.2 4.6e-11 42.8 7.2 3.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 ORY91078.1 - 2.7e-09 36.8 6.0 2.7e-09 36.8 6.0 3.4 3 0 0 3 3 3 2 PHD-finger HC2 PF07382.11 ORY91078.1 - 0.59 10.2 20.1 0.052 13.6 14.4 2.0 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 ASFV_J13L PF05568.11 ORY91078.1 - 1 9.1 7.0 1.7 8.3 7.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein H-kinase_dim PF02895.14 ORY91078.1 - 1.2 9.5 3.3 2.5 8.6 2.6 1.8 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain RasGEF PF00617.19 ORY91079.1 - 3.4e-32 112.1 0.0 7.7e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY91079.1 - 1.7e-08 34.7 7.8 1.1e-07 32.0 4.3 3.5 2 1 0 2 2 2 1 RasGEF N-terminal motif Nucleotid_trans PF03407.16 ORY91080.1 - 4.8e-24 85.5 0.1 7e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase ECSIT_C PF14784.6 ORY91080.1 - 0.11 12.8 0.0 1.6 9.1 0.0 2.6 3 0 0 3 3 3 0 C-terminal domain of the ECSIT protein Rieske PF00355.26 ORY91081.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain GREB1 PF15782.5 ORY91081.1 - 0.02 12.0 3.4 0.019 12.1 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IMUP PF15761.5 ORY91081.1 - 0.026 15.2 14.0 0.026 15.2 14.0 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein HEXIM PF15313.6 ORY91081.1 - 0.057 13.6 9.3 0.098 12.8 9.3 1.3 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein DUF908 PF06012.12 ORY91081.1 - 0.1 12.0 6.7 0.13 11.6 6.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Macoilin PF09726.9 ORY91081.1 - 0.25 9.9 10.0 0.31 9.5 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 ORY91081.1 - 0.63 8.0 8.6 0.8 7.6 8.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF755 PF05501.11 ORY91081.1 - 0.69 10.2 22.7 0.35 11.1 15.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Presenilin PF01080.17 ORY91081.1 - 1.2 7.8 10.1 1.6 7.4 10.1 1.1 1 0 0 1 1 1 0 Presenilin IHABP4_N PF16174.5 ORY91081.1 - 1.9 9.1 15.0 3 8.4 15.0 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SpoIIIAH PF12685.7 ORY91081.1 - 4.9 6.9 14.5 9 6.1 14.5 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Peptidase_S64 PF08192.11 ORY91081.1 - 8.6 4.7 18.4 42 2.4 0.0 2.0 1 1 1 2 2 2 0 Peptidase family S64 Zip PF02535.22 ORY91081.1 - 9 5.4 7.4 12 5.0 7.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter tRNA_bind PF01588.20 ORY91082.1 - 1.5e-24 85.9 0.0 2.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain PBP PF01161.20 ORY91083.1 - 3.5e-14 53.3 0.1 7.2e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PDZ_5 PF17817.1 ORY91084.1 - 0.0012 19.1 0.0 0.0042 17.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain MRC1 PF09444.10 ORY91086.1 - 3e-27 95.9 17.6 3e-27 95.9 17.6 6.1 5 1 0 6 6 6 1 MRC1-like domain Rb_C PF08934.10 ORY91086.1 - 0.68 9.7 6.3 0.28 11.0 2.0 2.5 2 0 0 2 2 2 0 Rb C-terminal domain HMG_box PF00505.19 ORY91087.1 - 1.4e-13 51.0 4.7 3e-13 50.0 4.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY91087.1 - 2e-11 44.3 3.8 6.3e-11 42.7 3.8 1.8 1 0 0 1 1 1 1 HMG-box domain F-protein PF00469.20 ORY91087.1 - 1.1 8.8 6.8 5.4 6.5 1.0 2.1 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef UDPGP PF01704.18 ORY91088.1 - 3.3e-60 203.9 0.0 4.1e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORY91088.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain MFS_1 PF07690.16 ORY91089.1 - 6e-34 117.5 9.0 6e-34 117.5 9.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY91089.1 - 3.7e-12 45.9 0.1 3.7e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY91089.1 - 0.00045 19.6 8.1 0.0026 17.1 5.6 3.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Zip PF02535.22 ORY91089.1 - 0.0018 17.5 0.1 0.0063 15.8 0.0 1.8 1 1 0 2 2 2 1 ZIP Zinc transporter MFS_1_like PF12832.7 ORY91089.1 - 0.0065 15.4 10.2 0.018 13.9 2.4 2.4 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 ORY91090.1 - 4e-31 108.2 30.4 6.3e-31 107.6 30.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY91090.1 - 6.5e-07 28.6 9.4 6.5e-07 28.6 9.4 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3487 PF11990.8 ORY91090.1 - 5 7.0 7.2 9.4 6.2 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF4625 PF15418.6 ORY91091.1 - 0.0036 17.6 0.1 0.0068 16.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) DUF4627 PF15425.6 ORY91091.1 - 0.073 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) RhoGAP PF00620.27 ORY91093.1 - 1.6e-40 138.4 0.6 3.4e-40 137.4 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DUF1708 PF08101.11 ORY91093.1 - 8.5e-05 21.9 0.6 0.00017 20.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) RRP7 PF12923.7 ORY91093.1 - 0.16 12.1 5.4 0.36 11.0 5.4 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SUIM_assoc PF16619.5 ORY91093.1 - 6.1 7.0 13.3 0.17 12.0 3.2 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 C2 PF00168.30 ORY91094.1 - 4e-80 264.7 5.8 6.9e-20 71.3 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF3678 PF12435.8 ORY91094.1 - 8.8 5.8 8.7 0.52 9.7 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) G-patch PF01585.23 ORY91095.1 - 5.5e-15 55.0 2.9 1.4e-14 53.7 2.9 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY91095.1 - 1.1e-05 25.4 2.3 1.1e-05 25.4 2.3 4.3 3 1 0 3 3 2 1 G-patch domain Nop14 PF04147.12 ORY91095.1 - 0.0068 14.7 33.5 0.0076 14.5 33.5 1.1 1 0 0 1 1 1 1 Nop14-like family eIF-3_zeta PF05091.12 ORY91095.1 - 0.59 9.1 22.5 0.74 8.7 22.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Red1 PF07964.11 ORY91095.1 - 1.9 6.6 42.6 2.2 6.4 42.6 1.0 1 0 0 1 1 1 0 Rec10 / Red1 CDC45 PF02724.14 ORY91095.1 - 1.9 6.7 37.7 2.7 6.2 37.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 ORY91095.1 - 2.4 6.2 30.5 3.1 5.8 30.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 ORY91095.1 - 2.6 8.6 15.8 3.4 8.2 15.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein LAP1C PF05609.12 ORY91095.1 - 3 6.9 29.1 3.6 6.6 29.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 ORY91095.1 - 4.9 5.8 29.0 7.7 5.2 29.0 1.4 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 ORY91095.1 - 5.5 6.8 44.4 8.8 6.1 44.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal 4HBT_3 PF13622.6 ORY91096.1 - 3.1e-33 116.1 0.0 3.8e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily GATA PF00320.27 ORY91097.1 - 2.1e-29 100.8 16.1 6.5e-15 54.4 5.1 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 ORY91097.1 - 8.2e-12 44.7 1.3 8.2e-12 44.7 1.3 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 ORY91097.1 - 0.00025 20.5 5.6 0.091 12.3 0.3 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY91097.1 - 0.00043 20.3 1.0 0.57 10.3 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain DZR PF12773.7 ORY91097.1 - 0.0086 16.1 5.0 0.12 12.4 5.5 2.7 1 1 2 3 3 3 2 Double zinc ribbon DUF5045 PF16464.5 ORY91097.1 - 0.015 15.6 0.3 0.015 15.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5045) eIF-5_eIF-2B PF01873.17 ORY91097.1 - 0.23 11.3 4.3 3.5 7.5 0.5 2.8 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 ORY91097.1 - 0.57 10.4 5.9 4.6 7.5 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MAT1 PF06391.13 ORY91097.1 - 3.4 7.5 21.2 7.4 6.3 11.7 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Vps36-NZF-N PF16988.5 ORY91097.1 - 8.9 5.8 14.4 15 5.0 0.1 4.4 2 2 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CLTH PF10607.9 ORY91098.1 - 2.4e-38 131.4 0.4 2.4e-38 131.4 0.4 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY91098.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 LisH CLZ PF16526.5 ORY91098.1 - 0.003 17.9 3.6 0.0088 16.4 3.6 1.8 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FH2 PF02181.23 ORY91098.1 - 0.011 14.9 1.8 0.018 14.2 1.8 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Ran-binding PF05508.11 ORY91098.1 - 0.011 14.8 3.9 0.02 13.9 3.9 1.3 1 0 0 1 1 1 0 RanGTP-binding protein QueC PF06508.13 ORY91098.1 - 0.12 11.9 0.7 0.53 9.7 0.2 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Trm112p PF03966.16 ORY91098.1 - 0.12 13.0 0.1 1.7 9.3 0.0 2.8 2 1 0 2 2 2 0 Trm112p-like protein HTH_37 PF13744.6 ORY91098.1 - 0.54 10.2 3.6 3.2 7.8 1.6 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain zf-C4H2 PF10146.9 ORY91098.1 - 2.3 8.5 9.4 6.5 7.0 7.8 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein Hydrolase_3 PF08282.12 ORY91100.1 - 1.8e-49 168.8 0.0 2.7e-49 168.2 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY91100.1 - 2.8e-12 46.7 0.0 1.1e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ORY91100.1 - 2.4e-06 28.0 0.0 0.00026 21.3 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY91100.1 - 0.0021 18.1 0.0 0.0057 16.7 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY91100.1 - 0.051 14.0 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Kinesin PF00225.23 ORY91101.1 - 4.1e-114 381.0 0.0 4.1e-114 381.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 ORY91101.1 - 5.4e-53 179.8 2.2 5.4e-53 179.8 2.2 3.3 3 0 0 3 3 3 1 Kinesin-associated DUF3694 PF12473.8 ORY91101.1 - 5e-42 144.2 0.0 1.7e-41 142.4 0.0 2.0 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 ORY91101.1 - 1.9e-29 102.5 0.0 5.8e-29 100.9 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 ORY91101.1 - 5e-15 55.9 0.1 1.8e-14 54.1 0.1 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.26 ORY91101.1 - 2.1e-07 31.2 0.5 8.2e-07 29.3 0.2 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 ORY91101.1 - 1.9e-06 28.2 0.4 1.9e-06 28.2 0.4 2.3 2 0 0 2 2 1 1 Kinesin protein 1B PH_9 PF15410.6 ORY91101.1 - 0.0038 17.6 0.1 0.021 15.2 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Yop-YscD_cpl PF16697.5 ORY91101.1 - 0.007 16.7 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YebO PF13974.6 ORY91101.1 - 4.1 7.6 7.4 30 4.8 0.1 3.1 2 0 0 2 2 2 0 YebO-like protein PH_11 PF15413.6 ORY91101.1 - 6 7.3 7.1 25 5.3 2.0 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain F-box PF00646.33 ORY91102.1 - 0.00028 20.7 4.5 0.0011 18.8 0.2 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORY91102.1 - 0.0017 18.2 0.7 0.0017 18.2 0.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY91102.1 - 0.0037 17.6 6.7 1 9.9 3.0 4.0 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 ORY91104.1 - 1e-15 57.3 0.0 1.2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY91104.1 - 0.055 13.6 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif DUF2958 PF11171.8 ORY91104.1 - 0.17 12.2 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) FAD_binding_6 PF00970.24 ORY91105.1 - 8.8e-34 115.8 0.0 1.3e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY91105.1 - 7.9e-32 110.2 0.0 1.2e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY91105.1 - 1.2e-07 31.9 0.0 0.00024 21.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF2052 PF09747.9 ORY91106.1 - 2.1 8.4 21.2 2.7 8.1 21.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) tRNA-synt_2b PF00587.25 ORY91107.1 - 7e-24 84.8 0.0 1e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORY91107.1 - 1.8e-09 37.8 1.3 3.1e-09 37.0 1.3 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FUSC_2 PF13515.6 ORY91108.1 - 1e-14 54.7 11.0 1e-14 54.7 11.0 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY91108.1 - 1.1e-14 54.9 1.6 1.5e-14 54.4 0.2 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORY91108.1 - 1.2e-14 54.2 0.1 1.2e-14 54.2 0.1 3.3 3 1 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 ORY91108.1 - 2.8e-07 29.5 11.2 2.8e-07 29.5 11.2 3.0 3 1 0 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 ORY91108.1 - 0.0028 16.6 8.6 0.0028 16.6 8.6 3.1 2 1 1 3 3 3 1 Aluminium activated malate transporter Adenine_glyco PF03352.13 ORY91108.1 - 0.079 12.7 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Methyladenine glycosylase TEA PF01285.18 ORY91108.1 - 0.11 12.6 0.1 0.42 10.7 0.1 2.0 1 0 0 1 1 1 0 TEA/ATTS domain DUF2953 PF11167.8 ORY91108.1 - 8.4 6.6 6.8 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) AAA PF00004.29 ORY91109.1 - 3.7e-41 140.7 0.0 7.6e-41 139.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY91109.1 - 1.5e-17 63.2 0.2 3.1e-17 62.3 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY91109.1 - 3.2e-08 33.2 1.0 5.8e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 ORY91109.1 - 2.2e-05 24.9 0.1 0.0057 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY91109.1 - 2.5e-05 24.3 0.1 0.00014 21.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY91109.1 - 0.00015 21.5 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY91109.1 - 0.00036 20.7 0.0 0.0021 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY91109.1 - 0.00058 20.1 0.3 0.062 13.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 ORY91109.1 - 0.0011 18.4 0.1 0.023 14.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 ORY91109.1 - 0.0018 17.5 0.0 0.0036 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 ORY91109.1 - 0.0025 17.2 0.1 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY91109.1 - 0.0048 17.1 0.1 0.012 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY91109.1 - 0.0061 16.4 0.3 0.36 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORY91109.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 ORY91109.1 - 0.035 13.5 0.2 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 ORY91109.1 - 0.046 14.3 0.3 0.23 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY91109.1 - 0.057 13.1 0.1 0.24 11.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY91109.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY91109.1 - 0.078 13.4 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 ORY91109.1 - 0.091 12.5 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 ORY91109.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ORY91109.1 - 0.19 10.8 0.4 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 MitMem_reg PF13012.6 ORY91110.1 - 9.3e-28 96.9 1.3 1.6e-27 96.2 1.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY91110.1 - 3.6e-17 62.4 0.0 7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TLV_coat PF00429.19 ORY91110.1 - 0.15 10.7 0.2 0.2 10.3 0.2 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) OTU PF02338.19 ORY91111.1 - 2.3e-14 54.0 0.0 4.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY91111.1 - 3.8e-05 23.3 0.2 0.069 12.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain CUE PF02845.16 ORY91111.1 - 0.027 14.2 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 CUE domain CPSF100_C PF13299.6 ORY91111.1 - 2.3 8.4 0.0 2.3 8.4 0.0 3.2 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal Zn_clus PF00172.18 ORY91112.1 - 0.0019 18.3 5.6 0.0039 17.3 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-rich_Ago1 PF12764.7 ORY91112.1 - 0.092 13.5 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut Exo_endo_phos PF03372.23 ORY91113.1 - 9.1e-08 31.9 0.0 3.6e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.6 ORY91113.1 - 0.02 14.7 0.0 0.064 13.1 0.0 1.9 1 0 0 1 1 1 0 UBA-like domain FTR1 PF03239.14 ORY91116.1 - 3.5e-67 226.7 10.5 4.4e-67 226.4 10.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Tmemb_14 PF03647.13 ORY91116.1 - 0.24 12.1 11.4 0.9 10.3 0.4 2.6 2 0 0 2 2 2 0 Transmembrane proteins 14C MgtE PF01769.16 ORY91116.1 - 0.91 9.9 12.9 1.8 9.0 3.8 2.6 2 0 0 2 2 2 0 Divalent cation transporter B12D PF06522.11 ORY91116.1 - 5.7 6.8 6.3 8.9 6.2 1.2 3.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Peptidase_U4 PF03419.13 ORY91116.1 - 6.5 6.0 13.1 0.22 10.8 3.6 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Phage_holin_3_6 PF07332.11 ORY91116.1 - 8.2 6.5 13.9 0.11 12.6 0.4 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Podoplanin PF05808.11 ORY91118.1 - 0.00027 21.1 0.1 0.00043 20.4 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Yip1 PF04893.17 ORY91118.1 - 0.033 13.9 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Yip1 domain SKG6 PF08693.10 ORY91118.1 - 0.056 12.9 0.4 0.056 12.9 0.4 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 ORY91118.1 - 4.4 7.1 0.0 4.4 7.1 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Apt1 PF10351.9 ORY91118.1 - 4.7 6.0 8.5 5.8 5.7 8.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peroxin-3 PF04882.12 ORY91118.1 - 9.5 5.1 5.9 14 4.6 5.9 1.3 1 0 0 1 1 1 0 Peroxin-3 Suc_Fer-like PF06999.12 ORY91119.1 - 1.2e-46 159.1 0.1 1.6e-46 158.7 0.1 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pterin_4a PF01329.19 ORY91121.1 - 5.1e-32 109.9 0.1 6e-32 109.7 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase GATA PF00320.27 ORY91123.1 - 2e-16 59.3 5.8 2.9e-16 58.8 5.8 1.3 1 0 0 1 1 1 1 GATA zinc finger Chordopox_RPO7 PF05864.12 ORY91123.1 - 0.061 13.6 0.1 0.095 13.0 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Abp2 PF09441.10 ORY91124.1 - 2.2e-22 79.9 0.0 4.7e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 ARS binding protein 2 Pox_A_type_inc PF04508.12 ORY91124.1 - 0.13 12.2 2.8 0.3 11.0 2.8 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DivIC PF04977.15 ORY91124.1 - 2.1 8.2 5.2 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator Kinesin PF00225.23 ORY91125.1 - 1.4e-108 362.8 0.6 1.4e-108 362.8 0.6 1.8 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY91125.1 - 7.6e-59 197.9 0.0 2.3e-58 196.4 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 ORY91125.1 - 0.21 12.0 1.4 12 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Desmo_N PF06771.11 ORY91125.1 - 0.24 11.8 3.8 6.7 7.1 0.4 2.7 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DUF3450 PF11932.8 ORY91125.1 - 0.52 9.6 23.0 0.27 10.5 11.2 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) DUF2937 PF11157.8 ORY91125.1 - 5.7 6.6 6.9 15 5.2 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Pro_dh PF01619.18 ORY91126.1 - 4.8e-74 249.6 2.6 1.1e-73 248.4 2.6 1.6 1 1 0 1 1 1 1 Proline dehydrogenase ThiF PF00899.21 ORY91127.1 - 1.9e-62 210.8 0.1 3.8e-62 209.8 0.1 1.4 2 0 0 2 2 2 1 ThiF family Rhodanese PF00581.20 ORY91127.1 - 6.7e-09 36.2 0.0 1.8e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_3 PF01494.19 ORY91127.1 - 0.018 14.3 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 ORY91127.1 - 0.097 12.7 0.2 0.65 10.0 0.0 2.3 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY91127.1 - 5.5 7.3 6.4 90 3.3 6.4 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thioredoxin PF00085.20 ORY91128.1 - 0.0002 21.3 0.1 0.00025 21.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin PB1 PF00564.24 ORY91129.1 - 0.00017 21.5 0.1 0.00064 19.6 0.1 2.1 1 1 0 1 1 1 1 PB1 domain PX PF00787.24 ORY91129.1 - 0.00076 19.4 2.8 0.0025 17.8 0.6 2.6 2 1 0 2 2 2 1 PX domain DNA_pol3_tau_5 PF12170.8 ORY91129.1 - 0.047 13.8 0.0 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha SRP-alpha_N PF04086.13 ORY91130.1 - 4.9e-57 194.1 10.9 7.4e-57 193.5 10.9 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 ORY91130.1 - 3.2e-49 167.2 0.0 6.4e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 ORY91130.1 - 2.7e-09 37.1 0.0 1.3e-08 34.9 0.0 2.3 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 ORY91130.1 - 1.3e-05 24.3 0.0 3.6e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORY91130.1 - 0.003 17.3 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ORY91130.1 - 0.027 14.5 0.0 0.094 12.8 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORY91130.1 - 0.047 14.1 0.1 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Fer4_NifH PF00142.18 ORY91130.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF4378 PF14309.6 ORY91130.1 - 0.1 13.0 0.4 0.3 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) FF PF01846.19 ORY91132.1 - 3.8e-40 135.8 12.8 2.7e-12 46.7 0.0 6.9 7 0 0 7 7 7 5 FF domain WW PF00397.26 ORY91132.1 - 1.1e-15 57.4 17.0 9.3e-09 35.2 6.6 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 ORY91132.1 - 6e-07 30.1 13.2 0.24 12.1 0.0 5.9 5 2 0 5 5 5 3 p190-A and -B Rho GAPs FF domain DUF1367 PF07105.11 ORY91132.1 - 0.37 10.4 3.4 9.2 5.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1367) ORC5_C PF14630.6 ORY91133.1 - 1.6e-68 231.3 0.1 2e-68 231.0 0.1 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 ORY91133.1 - 7.4e-14 52.5 0.0 2.1e-12 47.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY91133.1 - 0.00035 20.9 0.0 0.0013 19.0 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 ORY91133.1 - 0.0045 17.4 0.0 0.024 15.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ORY91133.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 ORY91133.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.25 ORY91135.1 - 7e-67 225.6 0.0 1e-66 225.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91135.1 - 2.7e-49 167.8 0.0 4.6e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 ORY91135.1 - 6.5e-07 29.6 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 ORY91135.1 - 2.7e-05 23.6 0.0 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORY91135.1 - 0.00044 19.1 0.0 0.00044 19.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY91135.1 - 0.021 14.7 0.1 0.24 11.3 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY91135.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY91135.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCM PF00493.23 ORY91136.1 - 7.4e-95 316.3 0.0 1.3e-94 315.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY91136.1 - 3.4e-33 114.2 0.0 6.4e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY91136.1 - 5.4e-25 87.6 1.3 1.4e-24 86.3 1.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY91136.1 - 3.2e-12 47.0 0.0 1.1e-11 45.2 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY91136.1 - 1.8e-08 34.0 0.2 1.5e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORY91136.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 ORY91136.1 - 0.016 15.1 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY91136.1 - 0.025 14.6 0.0 0.086 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TFB6 PF17110.5 ORY91136.1 - 3.9 7.2 8.2 9.2 6.0 5.3 2.7 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 ORY91136.1 - 8.6 5.6 6.7 14 4.9 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein RhoGAP PF00620.27 ORY91137.1 - 8.8e-39 132.8 0.0 2.7e-38 131.2 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 ORY91137.1 - 0.0039 17.4 0.1 0.021 15.1 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain FdhE PF04216.12 ORY91137.1 - 1.2 8.9 7.6 0.074 12.9 1.4 2.1 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation CRT10 PF08728.10 ORY91138.1 - 4.1e-07 28.6 0.1 4.6e-07 28.4 0.1 1.0 1 0 0 1 1 1 1 CRT10 WD40 PF00400.32 ORY91140.1 - 1.2e-07 32.2 7.9 1.3e-07 32.2 0.4 3.1 3 1 0 3 3 3 1 WD domain, G-beta repeat CRT10 PF08728.10 ORY91140.1 - 1.1e-06 27.1 0.3 7.3e-06 24.5 0.3 2.0 1 1 0 1 1 1 1 CRT10 ANAPC4_WD40 PF12894.7 ORY91140.1 - 0.04 14.2 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-T_C PF15511.6 ORY91141.1 - 2.6e-08 33.9 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY91141.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY91141.1 - 9.7e-05 22.7 0.1 0.00013 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY91141.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY91141.1 - 0.00035 20.8 0.1 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY91141.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY91141.1 - 0.059 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY91141.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF1691 PF07950.11 ORY91142.1 - 2e-11 44.5 3.3 3.6e-09 37.3 0.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Trp_oprn_chp PF09534.10 ORY91142.1 - 0.01 15.6 0.9 0.01 15.6 0.9 1.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SecG PF03840.14 ORY91142.1 - 0.19 11.8 2.4 0.36 10.9 2.4 1.5 1 0 0 1 1 1 0 Preprotein translocase SecG subunit UL73_N PF12522.8 ORY91142.1 - 2.4 8.0 16.4 4.2 7.2 16.4 1.4 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal p450 PF00067.22 ORY91143.1 - 1.5e-80 271.2 0.0 2e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.20 ORY91144.1 - 2.8e-145 484.8 11.1 3.4e-145 484.6 11.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY91144.1 - 3.6e-61 205.9 6.0 5.9e-60 202.0 1.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY91144.1 - 3.6e-15 56.1 3.3 2.7e-05 24.5 0.0 6.1 2 2 5 7 7 7 6 HEAT repeats HEAT PF02985.22 ORY91144.1 - 3.1e-06 27.0 4.5 0.015 15.5 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat Cnd3 PF12719.7 ORY91144.1 - 1.8e-05 24.1 0.2 0.00086 18.6 0.1 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 ORY91144.1 - 0.00021 21.7 0.2 0.3 11.6 0.0 4.3 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 ORY91144.1 - 0.0041 17.1 0.7 2.3 8.2 0.0 3.0 2 1 1 3 3 3 2 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 ORY91144.1 - 0.011 15.3 0.1 1.2 8.7 0.0 3.0 2 1 0 2 2 2 0 CLASP N terminal Atx10homo_assoc PF09759.9 ORY91144.1 - 0.052 13.6 0.4 14 5.8 0.0 3.5 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Sec7_N PF12783.7 ORY91144.1 - 0.069 13.1 0.4 0.35 10.8 0.2 2.3 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Glyco_hydro_25 PF01183.20 ORY91144.1 - 0.19 11.9 0.0 4.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 25 A_deaminase PF00962.22 ORY91145.1 - 4.7e-126 420.6 0.1 8e-126 419.8 0.1 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase Syntaxin PF00804.25 ORY91146.1 - 9.9e-15 54.7 10.2 5.5e-11 42.5 0.6 2.2 1 1 1 2 2 2 2 Syntaxin DUF5102 PF17104.5 ORY91146.1 - 0.0021 18.1 1.6 0.0024 18.0 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) SNARE PF05739.19 ORY91146.1 - 0.0022 18.0 0.3 0.0047 16.9 0.2 1.7 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 ORY91146.1 - 0.013 15.9 3.2 0.039 14.3 0.8 2.1 2 0 0 2 2 2 0 Syntaxin-like protein VitD-bind_III PF09164.10 ORY91146.1 - 0.058 13.4 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III FAM178 PF14816.6 ORY91147.1 - 1.7e-08 33.9 0.2 1.7e-08 33.9 0.2 2.2 2 0 0 2 2 2 1 Family of unknown function, FAM178 eRF1_2 PF03464.15 ORY91148.1 - 3.1e-45 153.7 0.1 5.2e-45 153.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORY91148.1 - 5.3e-35 120.3 0.1 1.1e-34 119.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 ORY91148.1 - 4e-22 78.6 0.0 6.6e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 ORY91148.1 - 5.2e-10 39.7 0.0 9.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 ORY91148.1 - 1.8e-08 34.8 0.0 2.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor RhoGEF PF00621.20 ORY91149.1 - 1.6e-37 129.6 5.1 3.7e-37 128.3 5.1 1.7 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 ORY91149.1 - 1.1e-31 108.9 0.2 2.5e-31 107.8 0.2 1.6 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 ORY91149.1 - 4.5e-25 88.3 3.0 1e-24 87.1 3.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 ORY91149.1 - 4.2e-17 61.9 0.1 1.2e-16 60.3 0.1 1.9 1 0 0 1 1 1 1 PB1 domain fn3_6 PF17766.1 ORY91149.1 - 0.00042 20.4 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type-III domain PH PF00169.29 ORY91149.1 - 0.001 19.5 0.3 0.007 16.9 0.3 2.5 2 0 0 2 2 2 1 PH domain NPV_P10 PF05531.12 ORY91149.1 - 0.031 14.7 3.0 0.4 11.2 1.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RNA_pol_3_Rpc31 PF11705.8 ORY91149.1 - 1.5 9.0 11.3 0.13 12.5 0.6 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 ORY91149.1 - 1.7 7.9 4.9 2.9 7.1 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.8 ORY91149.1 - 1.7 9.6 13.1 0.47 11.5 7.0 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ras PF00071.22 ORY91150.1 - 5.6e-55 185.4 0.0 6.4e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY91150.1 - 7.7e-20 71.3 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY91150.1 - 2.6e-07 30.3 0.1 3.3e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY91150.1 - 6.2e-05 22.6 0.2 0.0003 20.4 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY91150.1 - 0.001 19.0 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY91150.1 - 0.023 14.8 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY91150.1 - 0.023 14.2 0.2 0.12 11.9 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B CbiA PF01656.23 ORY91150.1 - 0.11 12.5 0.2 0.2 11.7 0.2 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 ORY91150.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 ORY91151.1 - 1.7e-20 73.2 0.2 3.9e-14 52.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY91151.1 - 4e-20 69.8 5.4 1.2e-05 24.5 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY91151.1 - 1.4e-19 68.3 0.4 1.9e-05 24.2 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 ORY91151.1 - 9.1e-11 40.8 6.0 0.0011 18.3 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ORY91151.1 - 1.2e-09 37.9 7.2 0.0006 19.6 0.8 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 ORY91151.1 - 8.4e-06 25.7 2.5 0.29 11.1 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY91151.1 - 0.047 14.0 0.1 1.3 9.4 0.0 2.6 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY91151.1 - 0.057 13.7 0.2 2.4 8.5 0.1 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L26 PF16906.5 ORY91152.1 - 2.6e-38 130.4 3.5 3.2e-38 130.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY91152.1 - 3.5e-08 33.1 4.7 4.4e-08 32.8 3.5 1.9 2 1 0 2 2 2 1 KOW motif DUF5617 PF18493.1 ORY91153.1 - 0.031 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) EKLF_TAD2 PF16833.5 ORY91153.1 - 0.33 11.0 1.8 0.65 10.1 1.8 1.5 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 2 Cyt-b5 PF00173.28 ORY91154.1 - 1.7e-20 72.9 0.1 3.9e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ORY91154.1 - 4.5e-13 49.7 18.5 4.5e-13 49.7 18.5 2.0 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 ORY91154.1 - 0.018 15.2 0.2 0.041 14.1 0.0 1.6 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region NTF2 PF02136.20 ORY91155.1 - 2.3e-27 95.9 0.0 2.3e-27 95.9 0.0 2.5 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ORY91155.1 - 1e-12 47.7 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SnoaL_2 PF12680.7 ORY91155.1 - 0.0049 17.5 0.0 0.014 16.0 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain Nup35_RRM_2 PF14605.6 ORY91155.1 - 0.041 13.9 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 ORY91155.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif CDC45 PF02724.14 ORY91155.1 - 1 7.6 17.2 2.3 6.4 17.2 1.6 1 0 0 1 1 1 0 CDC45-like protein Hexokinase_2 PF03727.16 ORY91156.1 - 6.2e-64 215.7 0.0 8.4e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY91156.1 - 1.5e-48 165.4 0.0 3.6e-48 164.1 0.0 1.6 2 0 0 2 2 2 1 Hexokinase F-box-like PF12937.7 ORY91157.1 - 6.2e-05 22.8 0.3 0.00017 21.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY91157.1 - 0.00023 21.0 0.0 0.00023 21.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain LMBR1 PF04791.16 ORY91157.1 - 0.22 10.4 6.4 0.29 10.0 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.13 ORY91157.1 - 0.71 9.8 8.7 8.4 6.3 6.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_S46 PF10459.9 ORY91157.1 - 1.8 7.1 12.4 2.5 6.6 12.4 1.1 1 0 0 1 1 1 0 Peptidase S46 TMEM119 PF15724.5 ORY91158.1 - 3.1 7.8 13.1 0.4 10.7 8.0 2.0 2 1 0 2 2 2 0 TMEM119 family PHD PF00628.29 ORY91159.1 - 5.8e-10 38.9 9.4 1.5e-09 37.6 6.8 2.5 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 ORY91159.1 - 0.00016 21.1 4.8 0.00043 19.8 1.3 2.6 2 0 0 2 2 2 1 PHD-finger zf-MYST PF17772.1 ORY91159.1 - 0.031 13.9 0.6 0.088 12.4 0.1 2.0 2 0 0 2 2 2 0 MYST family zinc finger domain zf-CW PF07496.15 ORY91159.1 - 0.18 11.9 5.9 0.044 13.8 1.4 2.3 2 0 0 2 2 2 0 CW-type Zinc Finger zf-RING_9 PF13901.6 ORY91159.1 - 0.58 10.1 13.0 0.14 12.1 9.5 1.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-FPG_IleRS PF06827.14 ORY91159.1 - 1.8 8.5 4.6 3.2 7.7 0.9 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS INTAP PF16617.5 ORY91159.1 - 3.7 7.9 11.3 1.9 8.9 6.9 2.9 2 1 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region zf-ribbon_3 PF13248.6 ORY91159.1 - 3.8 7.1 5.7 9.4 5.8 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-PHD-like PF15446.6 ORY91159.1 - 6.9 6.3 14.9 0.26 10.9 1.1 3.4 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain Zn-ribbon_8 PF09723.10 ORY91159.1 - 7.2 6.8 7.0 23 5.2 3.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L44 PF00935.19 ORY91160.1 - 2.7e-38 130.3 9.8 3.9e-38 129.8 9.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Aldo_ket_red PF00248.21 ORY91161.1 - 7e-53 179.7 0.0 1.3e-50 172.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sel1 PF08238.12 ORY91162.1 - 1.3e-22 79.7 13.8 0.0001 22.8 0.0 5.9 6 0 0 6 6 6 5 Sel1 repeat CS PF04969.16 ORY91162.1 - 4.8e-12 46.7 0.0 1.2e-11 45.4 0.0 1.7 1 0 0 1 1 1 1 CS domain DUF4366 PF14283.6 ORY91162.1 - 0.025 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TPR_2 PF07719.17 ORY91162.1 - 0.33 11.2 7.3 1.5e+02 2.9 0.5 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY91162.1 - 0.35 11.2 1.7 54 4.4 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat GN3L_Grn1 PF08701.11 ORY91166.1 - 4.9e-27 93.8 25.2 4.9e-27 93.8 25.2 2.3 1 1 1 2 2 2 1 GNL3L/Grn1 putative GTPase DUF5523 PF17661.1 ORY91166.1 - 7 6.2 27.9 8.1 6.0 27.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DEAD PF00270.29 ORY91167.1 - 3.2e-44 150.8 0.2 5.1e-44 150.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY91167.1 - 9.7e-28 96.7 3.0 1e-26 93.4 0.4 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY91167.1 - 7.2e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NAGidase PF07555.13 ORY91167.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase CMS1 PF14617.6 ORY91167.1 - 0.058 12.7 0.0 0.058 12.7 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 ORY91167.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain GRP PF07172.11 ORY91167.1 - 0.18 12.5 11.9 0.35 11.6 11.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family HLH PF00010.26 ORY91169.1 - 6.3e-11 42.1 1.1 1.1e-10 41.3 1.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1838 PF08894.11 ORY91169.1 - 0.077 12.7 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) MAP65_ASE1 PF03999.12 ORY91169.1 - 0.11 11.2 9.0 0.12 11.1 9.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Presenilin PF01080.17 ORY91169.1 - 0.93 8.2 3.5 1.1 7.9 3.5 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 ORY91169.1 - 2.8 6.5 5.8 3.1 6.4 5.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup O-FucT PF10250.9 ORY91170.1 - 8.8e-18 65.1 0.1 4.6e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase CHMI PF02962.15 ORY91170.1 - 0.089 13.1 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 5-carboxymethyl-2-hydroxymuconate isomerase DUF1400 PF07176.11 ORY91170.1 - 0.095 13.0 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Cep57_CLD_2 PF14197.6 ORY91170.1 - 0.23 11.6 1.6 9 6.5 0.7 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF5345 PF17280.2 ORY91171.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) PspB PF06667.12 ORY91171.1 - 0.48 10.5 1.5 2.2 8.4 1.5 2.1 2 0 0 2 2 2 0 Phage shock protein B zf-RING_2 PF13639.6 ORY91172.1 - 9.2e-08 32.3 8.5 9.2e-08 32.3 8.5 2.4 3 0 0 3 3 2 1 Ring finger domain FANCL_C PF11793.8 ORY91172.1 - 1.8e-05 24.8 5.5 4.2e-05 23.6 5.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 ORY91172.1 - 0.00014 22.1 5.6 0.00034 20.8 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY91172.1 - 0.00034 20.6 1.8 0.0011 19.0 1.8 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORY91172.1 - 0.005 16.7 7.1 0.022 14.6 7.1 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 ORY91172.1 - 0.013 15.6 7.9 0.031 14.4 7.9 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 ORY91172.1 - 0.014 15.2 9.4 0.039 13.8 9.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY91172.1 - 0.03 13.9 5.1 0.076 12.7 5.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 ORY91172.1 - 0.065 13.1 5.3 0.16 11.9 5.3 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 ORY91172.1 - 0.077 13.3 8.1 0.16 12.3 8.1 1.6 1 0 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 ORY91172.1 - 0.24 11.6 3.8 0.56 10.3 3.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 ORY91172.1 - 0.25 11.3 6.3 0.53 10.2 6.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 ORY91172.1 - 3.8 7.4 6.4 9.3 6.1 6.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CAP_GLY PF01302.25 ORY91174.1 - 1.3e-21 76.3 0.1 2.1e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain TPR_MLP1_2 PF07926.12 ORY91174.1 - 0.0069 16.4 20.1 0.0069 16.4 20.1 3.8 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 ORY91174.1 - 0.024 14.6 1.3 0.024 14.6 1.3 3.8 2 1 3 5 5 5 0 Laminin Domain II Phage_int_SAM_6 PF18644.1 ORY91174.1 - 0.037 14.1 0.1 0.037 14.1 0.1 2.2 3 0 0 3 3 3 0 Phage integrase SAM-like domain BLOC1_2 PF10046.9 ORY91174.1 - 0.042 14.2 1.0 0.042 14.2 1.0 4.9 2 1 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM184 PF15665.5 ORY91174.1 - 0.1 12.4 46.9 0.67 9.7 2.6 3.3 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B zf-CCHC_4 PF14392.6 ORY91174.1 - 0.22 11.3 0.2 0.45 10.3 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4407 PF14362.6 ORY91174.1 - 0.32 10.3 38.1 19 4.5 21.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 ORY91174.1 - 0.72 9.3 52.1 0.098 12.1 24.5 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 Leu_zip PF15294.6 ORY91174.1 - 2.5 7.5 32.7 5.8 6.4 3.4 2.3 1 1 1 2 2 2 0 Leucine zipper Hormone_1 PF00103.20 ORY91174.1 - 5 6.8 10.9 6.5 6.4 9.4 1.9 1 1 0 1 1 1 0 Somatotropin hormone family DUF3584 PF12128.8 ORY91174.1 - 7.4 3.9 48.9 0.57 7.6 38.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PNRC PF15365.6 ORY91175.1 - 2.3e-07 30.4 7.8 7.4e-07 28.8 7.8 2.0 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif TMF_DNA_bd PF12329.8 ORY91175.1 - 2.5 8.2 17.0 0.2 11.7 10.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_S3_C PF00189.20 ORY91176.1 - 1.9e-22 79.5 0.7 5.8e-22 78.0 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORY91176.1 - 6.1e-13 48.4 0.1 1e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORY91176.1 - 0.021 15.3 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 MutS_V PF00488.21 ORY91177.1 - 5.9e-72 241.7 0.5 1.1e-71 240.7 0.5 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY91177.1 - 3.7e-38 131.7 0.6 8.1e-38 130.6 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORY91177.1 - 6.5e-27 94.0 0.2 5.1e-26 91.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 ORY91177.1 - 1.5e-13 51.2 0.6 8.6e-13 48.7 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ORY91177.1 - 2.3e-08 34.2 2.8 1.3e-07 31.9 0.2 2.8 2 0 0 2 2 2 1 MutS family domain IV Mito_carr PF00153.27 ORY91178.1 - 1.2e-61 204.6 0.1 3e-20 71.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NUDE_C PF04880.13 ORY91179.1 - 1 9.8 7.9 1.3 9.5 7.9 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Hamartin PF04388.12 ORY91179.1 - 1.4 7.5 3.6 1.5 7.4 3.6 1.0 1 0 0 1 1 1 0 Hamartin protein HhH-GPD PF00730.25 ORY91180.1 - 3.4e-13 50.0 0.0 4.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 ORY91180.1 - 0.024 15.3 0.0 7.3 7.3 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain Sirohm_synth_C PF14823.6 ORY91180.1 - 0.081 12.6 0.2 4.7 6.9 0.0 2.5 2 1 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal MAM33 PF02330.16 ORY91181.1 - 5.6e-76 255.2 5.0 6.4e-76 255.0 5.0 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Lact-deh-memb PF09330.11 ORY91181.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding C2 PF00168.30 ORY91182.1 - 4e-25 88.1 0.1 4.8e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 C2 domain Ecl1 PF12855.7 ORY91183.1 - 7.3e-10 40.3 7.6 8.5e-10 40.1 7.6 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 ORY91183.1 - 0.016 15.3 4.7 0.034 14.2 4.7 1.6 1 0 0 1 1 1 0 MYND finger VATC PF18716.1 ORY91183.1 - 0.18 11.7 2.8 0.31 10.9 2.8 1.5 1 0 0 1 1 1 0 Vms1-associating treble clef domain IQCJ-SCHIP1 PF15157.6 ORY91183.1 - 1.9 8.3 4.2 2.6 7.9 4.2 1.3 1 1 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif RhoGEF PF00621.20 ORY91184.1 - 1.5e-24 87.3 0.0 2.4e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 ORY91184.1 - 1.4e-07 32.0 0.0 3.5e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 PH domain Sporozoite_P67 PF05642.11 ORY91184.1 - 0.031 12.4 1.7 0.036 12.2 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3971 PF13116.6 ORY91184.1 - 0.098 12.2 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF4781 PF16013.5 ORY91185.1 - 0.055 12.3 0.1 0.055 12.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) GPI-anchored PF10342.9 ORY91186.1 - 8e-11 42.6 0.1 8e-11 42.6 0.1 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Alpha_GJ PF03229.13 ORY91186.1 - 0.67 10.5 10.6 1.3 9.6 10.6 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J FSA_C PF10479.9 ORY91186.1 - 5.5 5.0 8.8 7.1 4.6 8.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TIP49 PF06068.13 ORY91187.1 - 1.6e-161 537.4 2.8 2.3e-161 536.8 2.8 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY91187.1 - 1.3e-28 98.9 0.7 3.4e-28 97.6 0.7 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORY91187.1 - 5.4e-08 33.3 2.3 0.00018 22.0 0.1 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY91187.1 - 3.4e-07 30.2 1.0 0.0084 15.9 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 ORY91187.1 - 8.9e-06 25.2 0.3 1.7e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 ORY91187.1 - 0.00033 21.1 0.1 0.0024 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 ORY91187.1 - 0.00064 19.2 1.4 0.058 12.8 0.5 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ORY91187.1 - 0.0015 18.8 0.4 0.18 12.0 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 ORY91187.1 - 0.0019 18.2 0.5 1 9.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 ORY91187.1 - 0.0041 17.1 0.1 4.2 7.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY91187.1 - 0.009 15.6 0.0 0.1 12.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 ORY91187.1 - 0.012 15.3 0.2 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 ORY91187.1 - 0.022 15.1 5.0 0.06 13.7 2.8 2.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY91187.1 - 0.037 14.3 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ORY91187.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RhoGAP PF00620.27 ORY91188.1 - 4.2e-15 55.9 1.2 4.2e-15 55.9 1.2 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ORY91188.1 - 1.1e-07 32.0 0.2 4.9e-07 29.9 0.2 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 ORY91188.1 - 0.0075 16.0 0.5 0.024 14.4 0.5 1.8 1 0 0 1 1 1 1 BAR domain of APPL family DUF3574 PF12098.8 ORY91188.1 - 0.12 12.2 0.1 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) Coleoptericin PF06286.11 ORY91188.1 - 0.17 12.0 0.9 1.7 8.8 0.1 2.6 3 0 0 3 3 3 0 Coleoptericin HSP70 PF00012.20 ORY91189.1 - 9.7e-06 24.0 0.0 1.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY91189.1 - 0.037 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein hDGE_amylase PF14701.6 ORY91190.1 - 2e-155 518.2 0.1 3e-155 517.7 0.1 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 ORY91190.1 - 5.4e-119 397.6 0.0 7.8e-119 397.0 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 ORY91190.1 - 1.2e-70 238.0 0.0 1.9e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme SBF_like PF13593.6 ORY91191.1 - 6.3e-87 291.8 19.1 7.5e-87 291.6 19.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 ORY91191.1 - 1.8e-11 44.1 14.1 4.1e-11 42.9 14.1 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family OTU PF02338.19 ORY91192.1 - 8.2e-27 94.2 0.0 8.2e-27 94.2 0.0 2.0 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY91192.1 - 2.5e-08 33.7 0.0 2.1e-07 30.7 0.0 2.3 1 1 0 1 1 1 1 Peptidase C65 Otubain Striatin PF08232.12 ORY91192.1 - 0.037 14.6 12.5 0.052 14.1 12.5 1.3 1 0 0 1 1 1 0 Striatin family PKK PF12474.8 ORY91192.1 - 6.1 7.0 23.9 4.9 7.3 20.6 2.3 2 1 1 3 3 3 0 Polo kinase kinase O-FucT PF10250.9 ORY91193.1 - 8.2e-21 75.1 1.3 1.4e-08 34.8 0.0 3.3 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase DUF4459 PF14673.6 ORY91193.1 - 0.19 11.7 0.6 2.7 7.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4459) LON_substr_bdg PF02190.16 ORY91194.1 - 4.6e-20 72.4 0.0 7.4e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-RING_UBOX PF13445.6 ORY91194.1 - 1.6e-11 44.0 25.6 6.1e-06 26.2 8.6 3.6 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY91194.1 - 1.7e-10 40.5 31.5 2.3e-08 33.7 15.2 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY91194.1 - 3.4e-10 39.9 26.9 2.5e-05 24.3 9.6 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY91194.1 - 2.1e-09 37.1 27.0 2.1e-06 27.5 11.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY91194.1 - 4.3e-08 32.9 30.8 7.5e-07 28.9 14.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY91194.1 - 1.2e-07 31.9 29.9 5.7e-06 26.6 14.7 3.0 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 ORY91194.1 - 3.1e-05 23.8 31.8 0.00025 20.9 15.4 2.6 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY91194.1 - 0.0006 19.6 28.5 0.0022 17.8 12.8 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY91194.1 - 0.00071 19.4 5.8 0.00071 19.4 5.8 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 ORY91194.1 - 0.0068 16.5 9.5 0.0068 16.5 9.5 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 ORY91194.1 - 0.14 11.9 19.5 0.99 9.2 6.3 3.7 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 ORY91194.1 - 0.31 11.0 14.6 0.56 10.2 2.2 2.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Sugar_tr PF00083.24 ORY91195.1 - 4.4e-78 263.1 25.3 5.3e-78 262.9 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY91195.1 - 8e-20 71.1 41.8 2.5e-19 69.4 37.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MaoC_dehydrat_N PF13452.6 ORY91196.1 - 5.6e-05 23.3 0.0 0.0011 19.1 0.0 2.4 1 1 2 3 3 3 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 ORY91196.1 - 0.0002 20.9 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain zf-CCCH_4 PF18044.1 ORY91197.1 - 3e-08 33.3 2.7 5.5e-08 32.4 2.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY91197.1 - 9.1e-07 28.7 6.8 1.7e-06 27.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORY91197.1 - 2.7e-06 27.2 2.0 2.7e-06 27.2 2.0 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY91197.1 - 0.0073 17.0 0.8 0.017 15.8 0.8 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 ORY91197.1 - 2.9 8.5 5.5 6.2 7.5 5.5 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SART-1 PF03343.13 ORY91198.1 - 0.048 12.2 31.9 0.097 11.2 31.9 1.4 1 0 0 1 1 1 0 SART-1 family DSPc PF00782.20 ORY91199.1 - 2.7e-32 111.4 0.1 6.1e-31 107.0 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY91199.1 - 0.00031 20.9 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 ORY91199.1 - 0.0067 16.0 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CAP_N PF01213.19 ORY91199.1 - 2.3 7.6 10.6 0.9 9.0 0.8 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Aldo_ket_red PF00248.21 ORY91201.1 - 8.1e-52 176.2 0.0 8.9e-51 172.8 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_16 PF10294.9 ORY91202.1 - 0.0011 18.7 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase RAMP PF04901.13 ORY91202.1 - 0.0023 17.9 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Receptor activity modifying family Methyltransf_16 PF10294.9 ORY91203.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase AAA PF00004.29 ORY91204.1 - 1.7e-07 31.7 0.0 2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY91204.1 - 6.8e-06 26.6 0.1 1.7e-05 25.3 0.1 1.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 ORY91204.1 - 0.00031 20.8 0.0 0.00041 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY91204.1 - 0.00054 19.8 0.0 0.00063 19.6 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 ORY91204.1 - 0.0011 19.3 0.1 0.0014 18.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY91204.1 - 0.0052 17.1 0.0 0.008 16.6 0.0 1.4 1 1 0 1 1 1 1 RNA helicase SRP54 PF00448.22 ORY91204.1 - 0.007 16.0 0.1 0.0088 15.7 0.1 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 ORY91204.1 - 0.0075 15.8 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 ORY91204.1 - 0.0089 16.0 0.3 0.024 14.6 0.1 1.7 1 1 1 2 2 2 1 NACHT domain AAA_33 PF13671.6 ORY91204.1 - 0.0091 16.2 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY91204.1 - 0.0096 15.1 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY91204.1 - 0.01 16.4 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORY91204.1 - 0.017 15.0 0.2 0.024 14.5 0.2 1.2 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 ORY91204.1 - 0.019 14.9 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORY91204.1 - 0.028 14.3 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 ORY91204.1 - 0.029 14.1 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY91204.1 - 0.03 14.1 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORY91204.1 - 0.04 13.1 1.0 0.077 12.2 0.9 1.5 1 1 1 2 2 2 0 NB-ARC domain ATPase PF06745.13 ORY91204.1 - 0.041 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 ORY91204.1 - 0.046 13.7 0.0 0.054 13.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY91204.1 - 0.055 13.3 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY91204.1 - 0.093 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DLIC PF05783.11 ORY91204.1 - 0.097 11.5 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ATPase_2 PF01637.18 ORY91204.1 - 0.12 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 ORY91205.1 - 5.2e-41 140.2 0.0 9e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY91205.1 - 2.6e-18 65.5 1.3 5.1e-09 35.8 0.6 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY91205.1 - 7.5e-07 29.7 3.2 7.4e-05 23.2 0.1 3.4 2 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 ORY91205.1 - 8.9e-05 22.8 0.3 0.091 13.0 0.0 3.7 2 1 1 4 4 4 1 AAA domain RuvB_N PF05496.12 ORY91205.1 - 0.00016 21.5 0.0 0.00095 18.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 ORY91205.1 - 0.00055 19.9 0.1 0.016 15.1 0.0 2.5 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea TIP49 PF06068.13 ORY91205.1 - 0.00063 19.1 0.1 0.002 17.4 0.0 1.8 2 1 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 ORY91205.1 - 0.00077 19.5 0.2 0.0031 17.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 ORY91205.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 ORY91205.1 - 0.002 18.5 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 ORY91205.1 - 0.0025 17.9 0.0 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY91205.1 - 0.0029 18.1 0.0 0.0061 17.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 ORY91205.1 - 0.0033 16.6 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 ORY91205.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY91205.1 - 0.0075 16.2 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_2 PF07724.14 ORY91205.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY91205.1 - 0.008 16.3 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY91205.1 - 0.0084 16.7 0.0 0.028 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 ORY91205.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 ORY91205.1 - 0.014 15.0 0.1 0.029 13.9 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 ORY91205.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 ORY91205.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ORY91205.1 - 0.018 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 ORY91205.1 - 0.02 14.6 0.0 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 ORY91205.1 - 0.023 13.5 0.1 0.036 12.9 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein SRPRB PF09439.10 ORY91205.1 - 0.026 14.0 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 ORY91205.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 ORY91205.1 - 0.083 12.5 0.2 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 ORY91205.1 - 0.096 12.1 0.0 2 7.8 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein AAA_21 PF13304.6 ORY91205.1 - 0.1 12.4 0.1 0.28 11.0 0.0 1.7 2 1 0 2 2 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY91205.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORY91205.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_lig_T4_1 PF09511.10 ORY91207.1 - 5.4e-68 229.1 0.0 7.5e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 RNA ligase RNA_ligase PF09414.10 ORY91207.1 - 0.0096 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Nfu_N PF08712.11 ORY91207.1 - 0.066 13.3 0.3 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal PK_C PF02887.16 ORY91207.1 - 0.18 12.1 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain PAP_central PF04928.17 ORY91208.1 - 2.7e-35 121.6 0.0 3.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain Polbeta PF18765.1 ORY91208.1 - 2.6e-05 24.2 0.0 0.00029 20.9 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase PAP_RNA-bind PF04926.15 ORY91208.1 - 5.2e-05 22.9 0.0 9.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY91208.1 - 9.1e-05 22.7 0.1 0.00026 21.2 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ORY91208.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain MMR_HSR1_Xtn PF16897.5 ORY91209.1 - 1.7e-43 147.0 1.1 1.2e-42 144.3 0.5 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 ORY91209.1 - 1.8e-22 79.2 0.1 3.4e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 ORY91209.1 - 2e-21 76.2 0.1 6.2e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY91209.1 - 6.2e-12 45.3 0.1 3.1e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 ORY91209.1 - 0.002 17.2 1.2 0.006 15.6 0.4 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 ORY91209.1 - 0.0027 17.8 0.2 1.1 9.3 0.0 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 ORY91209.1 - 0.049 13.2 0.5 15 5.1 0.1 3.5 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY91209.1 - 1.5 8.7 3.7 6.3 6.7 0.5 3.0 2 2 1 3 3 3 0 RsgA GTPase DUF1479 PF07350.12 ORY91210.1 - 5.1e-140 466.9 0.0 6.1e-140 466.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 ORY91210.1 - 0.0011 19.3 0.0 0.99 9.6 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Hepar_II_III_N PF16889.5 ORY91210.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 Heparinase II/III N-terminus Glyco_hydro_15 PF00723.21 ORY91211.1 - 4.4e-39 134.5 0.0 6.2e-36 124.1 0.0 3.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF3176 PF11374.8 ORY91212.1 - 1.4e-12 47.7 0.2 4.1e-12 46.3 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) SBF_like PF13593.6 ORY91214.1 - 1.3e-86 290.8 20.3 1.5e-86 290.5 20.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 ORY91214.1 - 6.8e-12 45.5 13.6 6.8e-12 45.5 13.6 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family cNMP_binding PF00027.29 ORY91215.1 - 1.1e-38 131.2 0.1 6.2e-20 71.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Gluconate_2-dh3 PF13618.6 ORY91215.1 - 0.021 15.0 0.0 0.06 13.6 0.0 1.6 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 ER_lumen_recept PF00810.18 ORY91216.1 - 9.7e-54 182.2 13.6 1.5e-53 181.6 13.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ORY91216.1 - 0.11 12.3 11.4 0.84 9.5 0.4 3.8 3 1 1 5 5 5 0 PQ loop repeat Peptidase_M50 PF02163.22 ORY91217.1 - 1.7e-14 53.7 0.0 8.9e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 ORY91217.1 - 0.18 12.2 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain CDT1_C PF16679.5 ORY91220.1 - 1.8 9.1 6.1 3 8.3 3.1 2.3 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain FAD_binding_2 PF00890.24 ORY91221.1 - 2.1e-75 254.4 4.5 3e-75 253.9 4.5 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY91221.1 - 5.3e-14 52.6 1.4 1.5e-09 37.9 0.2 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY91221.1 - 2.1e-08 34.3 0.8 1.2e-06 28.7 0.3 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY91221.1 - 1e-07 31.0 3.3 0.00011 21.0 1.3 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 ORY91221.1 - 2.4e-07 30.3 1.1 8.9e-06 25.1 1.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY91221.1 - 7.2e-07 28.6 1.8 0.00087 18.5 1.3 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORY91221.1 - 1.2e-06 28.1 0.9 2e-06 27.5 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY91221.1 - 0.0003 20.1 0.1 0.059 12.6 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY91221.1 - 0.0012 18.9 0.0 0.0041 17.1 0.0 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORY91221.1 - 0.0025 17.1 0.3 0.0089 15.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 ORY91221.1 - 0.0088 15.1 0.6 0.014 14.5 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein SpoIIE PF07228.12 ORY91221.1 - 0.019 14.9 0.3 0.062 13.2 0.1 1.8 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) AlaDh_PNT_C PF01262.21 ORY91221.1 - 0.021 14.1 0.6 0.039 13.2 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ORY91221.1 - 0.22 12.1 0.7 0.45 11.1 0.5 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Acyltransferase PF01553.21 ORY91222.1 - 5.8e-12 45.4 0.1 8.4e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY91222.1 - 2.5e-10 40.3 0.3 7e-10 38.9 0.3 1.8 1 0 0 1 1 1 1 Acyltransferase C-terminus ABC_export PF16962.5 ORY91222.1 - 0.037 12.5 0.2 0.047 12.1 0.2 1.1 1 0 0 1 1 1 0 Putative ABC exporter Cellulase PF00150.18 ORY91223.1 - 6.8e-13 48.7 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 ORY91223.1 - 0.0073 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SnoaL_2 PF12680.7 ORY91224.1 - 0.033 14.8 0.1 0.26 12.0 0.0 2.4 3 0 0 3 3 3 0 SnoaL-like domain RNA_pol_Rpb6 PF01192.22 ORY91225.1 - 7.2e-17 61.1 0.0 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF2553 PF10830.8 ORY91225.1 - 0.8 10.6 4.2 14 6.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2553) MFS_1 PF07690.16 ORY91226.1 - 4.9e-54 183.6 36.0 1.7e-52 178.6 22.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY91226.1 - 7.6e-16 58.0 5.1 7.6e-16 58.0 5.1 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 ORY91226.1 - 7.1e-07 27.9 9.0 0.00028 19.3 2.2 2.6 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 ORY91226.1 - 0.00017 20.2 3.6 0.00026 19.5 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY91226.1 - 0.0003 19.3 0.9 0.0003 19.3 0.9 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_5 PF05631.14 ORY91226.1 - 0.012 14.6 0.4 0.012 14.6 0.4 2.5 3 0 0 3 3 3 0 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 ORY91226.1 - 0.34 9.7 24.8 0.1 11.5 5.6 3.7 3 1 1 4 4 4 0 MFS_1 like family DUF3425 PF11905.8 ORY91227.1 - 2.3e-13 50.2 0.6 1.2e-12 47.8 0.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORY91227.1 - 7.2e-08 32.4 4.7 7.2e-08 32.4 4.7 2.7 2 0 0 2 2 2 1 bZIP transcription factor SHE3 PF17078.5 ORY91227.1 - 0.1 12.3 1.6 0.18 11.5 1.6 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 ORY91227.1 - 0.36 10.9 20.6 0.27 11.3 13.4 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF349 PF03993.12 ORY91227.1 - 0.66 10.3 5.6 1.7 9.0 5.6 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF3043 PF11241.8 ORY91227.1 - 3.6 7.6 5.8 0.99 9.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Pkinase PF00069.25 ORY91228.1 - 1.3e-67 228.0 0.0 1.8e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91228.1 - 3.6e-52 177.2 0.0 5.8e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY91228.1 - 1e-07 31.6 0.0 0.00023 20.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SAM_2 PF07647.17 ORY91228.1 - 2.1e-05 24.5 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 ORY91228.1 - 0.00023 21.4 0.0 0.00055 20.2 0.0 1.7 1 1 0 1 1 1 1 Ras-binding domain of Byr2 Pkinase_fungal PF17667.1 ORY91228.1 - 0.00065 18.6 1.3 0.0009 18.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORY91228.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_1 PF00536.30 ORY91228.1 - 0.023 15.2 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) APH PF01636.23 ORY91228.1 - 0.1 12.5 0.6 0.46 10.4 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family DPBB_1 PF03330.18 ORY91229.1 - 5.3e-07 29.8 0.1 7.3e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY91229.1 - 0.1 12.5 0.5 0.17 11.7 0.2 1.5 1 1 0 1 1 1 0 Barwin family Big_3_5 PF16640.5 ORY91229.1 - 0.16 12.2 0.5 0.16 12.2 0.5 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) zinc_ribbon_2 PF13240.6 ORY91229.1 - 2.7 7.8 5.7 9 6.2 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Ras PF00071.22 ORY91230.1 - 8.5e-31 106.7 0.1 1e-30 106.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY91230.1 - 6e-24 84.6 0.1 8.3e-24 84.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY91230.1 - 3.7e-08 33.0 0.1 4.7e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY91230.1 - 0.00013 21.5 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 ORY91230.1 - 0.00063 18.7 0.2 0.28 10.0 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 ORY91230.1 - 0.0033 17.5 0.1 0.0059 16.7 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 ORY91230.1 - 0.0073 15.7 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein GTP_EFTU PF00009.27 ORY91230.1 - 0.18 11.3 0.3 4.3 6.8 0.3 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HlyIII PF03006.20 ORY91231.1 - 2.4e-53 181.1 27.7 2.9e-53 180.9 27.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related BacA PF02673.18 ORY91231.1 - 1.9 8.1 9.5 4 7.1 0.7 2.5 1 1 2 3 3 3 0 Bacitracin resistance protein BacA Pkinase PF00069.25 ORY91232.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ORY91233.1 - 9.5e-09 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91233.1 - 0.00014 21.2 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 ORY91234.1 - 0.00056 20.1 3.6 0.0015 18.8 3.6 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY91234.1 - 0.0019 18.1 1.8 0.0024 17.9 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY91234.1 - 0.002 17.9 0.6 0.0073 16.1 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY91234.1 - 0.002 18.2 0.9 0.017 15.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY91234.1 - 0.029 15.2 0.6 14 6.8 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY91234.1 - 0.042 14.3 3.1 0.41 11.2 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Tubulin_C PF03953.17 ORY91235.1 - 3e-50 169.6 0.0 5e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 ORY91235.1 - 1.1e-45 156.3 0.0 1.5e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 ORY91235.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain BIRC6 PF12356.8 ORY91236.1 - 0.016 14.6 0.4 0.029 13.8 0.3 1.4 1 1 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 HLH PF00010.26 ORY91237.1 - 1.8e-17 63.0 1.7 1.8e-17 63.0 1.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.24 ORY91238.1 - 1.8e-104 350.1 27.8 2.1e-104 349.9 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY91238.1 - 1e-19 70.7 54.1 1.9e-15 56.7 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 ORY91239.1 - 3.3e-48 163.7 0.1 2.4e-24 86.4 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY91239.1 - 1.2e-14 54.8 0.0 0.0061 16.4 0.0 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY91239.1 - 3.2e-14 52.9 0.1 7.6e-05 22.2 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY91239.1 - 4.4e-09 37.1 0.8 0.011 16.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORY91239.1 - 6.9e-09 35.8 0.1 0.00048 20.1 0.1 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA PF00004.29 ORY91239.1 - 2.4e-07 31.3 0.0 0.094 13.1 0.0 5.0 4 1 1 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY91239.1 - 3.6e-07 29.8 0.1 0.019 14.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY91239.1 - 3.8e-07 30.4 0.0 0.17 12.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 ORY91239.1 - 5.7e-07 29.6 0.0 0.018 15.2 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_28 PF13521.6 ORY91239.1 - 1.1e-06 28.9 0.2 0.024 14.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY91239.1 - 2e-06 28.3 1.2 0.079 13.3 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 ORY91239.1 - 6.1e-06 26.8 0.0 0.033 14.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORY91239.1 - 1e-05 25.9 0.0 0.29 11.5 0.0 3.4 3 0 0 3 3 3 2 RNA helicase MeaB PF03308.16 ORY91239.1 - 1.2e-05 24.4 0.2 0.061 12.3 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB 4HB PF17947.1 ORY91239.1 - 2e-05 24.5 0.0 0.00011 22.2 0.0 2.3 1 0 0 1 1 1 1 Four helical bundle domain AAA_15 PF13175.6 ORY91239.1 - 3.9e-05 23.5 3.4 0.1 12.3 0.0 3.2 4 0 0 4 4 2 2 AAA ATPase domain Chromo PF00385.24 ORY91239.1 - 5.2e-05 23.1 1.2 0.0003 20.6 0.2 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_33 PF13671.6 ORY91239.1 - 5.2e-05 23.4 0.0 0.94 9.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ORY91239.1 - 8.4e-05 22.4 2.3 0.85 9.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 ORY91239.1 - 0.00016 21.7 0.4 0.19 11.6 0.0 3.1 3 0 0 3 3 3 1 NACHT domain DUF815 PF05673.13 ORY91239.1 - 0.00023 20.4 0.0 0.31 10.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PduV-EutP PF10662.9 ORY91239.1 - 0.0006 19.6 0.0 0.43 10.3 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 ORY91239.1 - 0.0021 17.9 0.3 0.43 10.3 0.0 3.3 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SbcCD_C PF13558.6 ORY91239.1 - 0.0026 18.0 0.0 0.54 10.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ORY91239.1 - 0.0026 17.7 0.1 2.8 7.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 ORY91239.1 - 0.0048 16.9 0.0 2.6 8.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain Adaptin_N PF01602.20 ORY91239.1 - 0.005 15.5 1.3 0.29 9.6 0.2 2.4 1 1 0 2 2 2 1 Adaptin N terminal region Zeta_toxin PF06414.12 ORY91239.1 - 0.0099 15.2 0.1 2 7.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 ORY91239.1 - 0.01 15.0 0.3 1.2 8.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_27 PF13514.6 ORY91239.1 - 0.011 15.3 0.0 5.5 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ORY91239.1 - 0.012 15.7 0.7 1.1 9.3 0.0 3.1 3 0 0 3 3 2 0 Dynamin family AAA_13 PF13166.6 ORY91239.1 - 0.016 13.9 3.0 2.6 6.6 0.1 3.6 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 ORY91239.1 - 0.024 14.4 0.1 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORY91239.1 - 0.034 13.3 0.1 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 ORY91239.1 - 0.035 13.6 1.9 2.8 7.4 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region PRK PF00485.18 ORY91239.1 - 0.045 13.5 0.0 2 8.1 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 ORY91239.1 - 0.045 13.8 5.9 0.86 9.6 0.1 3.9 4 0 0 4 4 3 0 Helicase HerA, central domain Roc PF08477.13 ORY91239.1 - 0.048 13.9 0.0 16 5.7 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 ORY91239.1 - 0.049 13.4 0.0 13 5.4 0.0 3.3 3 0 0 3 3 2 0 IstB-like ATP binding protein TsaE PF02367.17 ORY91239.1 - 0.055 13.5 0.1 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 ORY91239.1 - 0.063 12.9 0.0 0.28 10.8 0.0 1.9 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 ORY91239.1 - 0.076 12.9 0.1 11 5.9 0.2 2.9 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 ORY91239.1 - 0.093 12.5 0.0 1.4 8.6 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase Viral_helicase1 PF01443.18 ORY91239.1 - 0.11 12.2 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FeoB_N PF02421.18 ORY91239.1 - 0.12 11.8 0.1 11 5.6 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 ORY91239.1 - 0.18 11.7 6.1 1.9 8.4 0.0 3.5 3 1 0 3 3 2 0 ATPase domain predominantly from Archaea BLOC1_2 PF10046.9 ORY91240.1 - 0.0013 19.0 5.4 0.0021 18.3 2.9 2.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 T2SSM PF04612.12 ORY91240.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M Snapin_Pallidin PF14712.6 ORY91240.1 - 0.017 15.5 3.3 0.025 15.0 1.4 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Med9 PF07544.13 ORY91240.1 - 0.024 14.7 0.6 0.024 14.7 0.6 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 THOC7 PF05615.13 ORY91240.1 - 0.033 14.5 3.0 0.064 13.5 3.0 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 Syntaxin-6_N PF09177.11 ORY91240.1 - 0.039 14.5 4.4 0.067 13.7 4.4 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Helo_like_N PF17111.5 ORY91240.1 - 0.052 12.9 3.7 0.03 13.7 1.5 1.6 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins TssO PF17561.2 ORY91240.1 - 0.065 13.3 1.3 0.25 11.5 0.2 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssO NPV_P10 PF05531.12 ORY91240.1 - 0.078 13.4 0.9 0.38 11.2 0.7 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 ORY91240.1 - 0.59 10.2 7.2 0.062 13.3 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2721 PF11026.8 ORY91241.1 - 0.027 14.4 0.1 0.032 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) zf-CCCH PF00642.24 ORY91242.1 - 4e-22 77.6 17.4 2.4e-11 43.2 4.9 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY91242.1 - 4.7e-13 48.7 19.2 1.1e-06 28.5 7.4 2.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORY91242.1 - 7.9e-13 47.9 14.2 7.8e-07 28.7 3.7 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY91242.1 - 6.7e-06 26.4 10.6 0.0011 19.3 1.8 2.5 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY91242.1 - 0.0052 17.5 9.9 0.043 14.5 1.7 2.1 1 1 1 2 2 2 2 Torus domain oligo_HPY PF08352.12 ORY91242.1 - 0.36 11.4 8.7 0.6 10.7 1.8 2.1 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCHH PF10283.9 ORY91242.1 - 5.8 7.0 15.6 1.6 8.8 1.4 3.3 3 1 0 3 3 3 0 PBZ domain Sds3 PF08598.11 ORY91243.1 - 1.5e-07 31.6 10.8 2.1e-07 31.2 10.8 1.2 1 0 0 1 1 1 1 Sds3-like Peptidase_S49_N PF08496.10 ORY91243.1 - 0.75 9.8 3.2 2.4 8.2 3.2 1.9 1 1 0 1 1 1 0 Peptidase family S49 N-terminal zf-C4H2 PF10146.9 ORY91243.1 - 1.5 9.1 9.0 2.6 8.3 9.0 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1325 PF07039.11 ORY91245.1 - 5e-06 26.6 1.3 0.00016 21.7 0.0 2.5 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 ORY91245.1 - 1.3e-05 25.2 0.1 2.2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) SMN PF06003.12 ORY91245.1 - 1.6e-05 24.3 2.3 1.8e-05 24.1 0.1 1.9 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) Tudor_2 PF18104.1 ORY91245.1 - 0.00024 20.7 0.1 0.00052 19.6 0.1 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 ORY91245.1 - 0.00033 20.4 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR PF00567.24 ORY91245.1 - 0.00042 20.3 0.6 0.0053 16.8 0.0 2.1 2 0 0 2 2 2 1 Tudor domain LBR_tudor PF09465.10 ORY91245.1 - 0.00096 18.9 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain 53-BP1_Tudor PF09038.10 ORY91245.1 - 0.06 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor DUF2730 PF10805.8 ORY91245.1 - 0.17 12.0 4.7 0.21 11.7 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) EB PF01683.18 ORY91246.1 - 0.00052 20.2 34.4 0.0022 18.2 5.9 3.8 2 1 2 4 4 4 3 EB module DUF4381 PF14316.6 ORY91246.1 - 0.0023 18.2 0.1 0.0041 17.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) LMBR1 PF04791.16 ORY91246.1 - 0.13 11.1 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ysc84 PF04366.12 ORY91247.1 - 2.6e-44 150.1 0.5 4.2e-44 149.4 0.5 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORY91247.1 - 4.6e-16 58.2 0.2 8.9e-16 57.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY91247.1 - 1.5e-12 47.2 0.1 2.8e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY91247.1 - 1e-10 41.1 0.0 2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 ORY91247.1 - 0.15 11.8 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) GTP_EFTU PF00009.27 ORY91248.1 - 2.7e-18 66.2 0.0 3.8e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY91248.1 - 0.0015 18.5 0.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 ORY91248.1 - 0.011 16.2 0.1 0.028 14.9 0.1 1.7 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 ORY91248.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORY91248.1 - 0.016 15.6 0.0 0.071 13.5 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu domain 2 PduV-EutP PF10662.9 ORY91248.1 - 0.027 14.2 0.1 0.51 10.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 ORY91248.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin Peptidase_S8 PF00082.22 ORY91249.1 - 3.8e-38 131.4 3.8 7.3e-38 130.5 3.8 1.4 1 1 0 1 1 1 1 Subtilase family Tmemb_9 PF05434.11 ORY91250.1 - 0.02 14.8 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 TMEM9 DUF3446 PF11928.8 ORY91250.1 - 0.12 12.7 3.7 3.3 8.1 1.7 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Herpes_LMP1 PF05297.11 ORY91250.1 - 0.17 11.1 3.7 0.57 9.3 0.0 2.0 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Chorion_2 PF03964.15 ORY91250.1 - 1.5 9.7 8.8 4.1 8.3 1.7 2.1 2 0 0 2 2 2 0 Chorion family 2 SR-25 PF10500.9 ORY91250.1 - 6.3 6.3 10.4 10 5.7 2.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pyrid_ox_like PF16242.5 ORY91253.1 - 2.3e-27 95.4 0.0 4.1e-27 94.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 ORY91253.1 - 5.4e-11 42.5 0.0 1.9e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DNA_pol_E_B PF04042.16 ORY91254.1 - 1.4e-42 145.5 0.0 2.3e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ORY91254.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Apt1 PF10351.9 ORY91255.1 - 8.6e-74 249.1 0.3 8.6e-74 249.1 0.3 3.0 2 1 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 ORY91255.1 - 8.2e-43 147.0 8.3 9.5e-40 136.9 0.1 3.2 2 1 1 3 3 3 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 ORY91255.1 - 6.1e-37 127.1 0.0 1.2e-36 126.1 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 ORY91255.1 - 8.9e-20 71.2 0.0 4.1e-19 69.0 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 ORY91255.1 - 1.5e-06 28.9 0.7 4.5e-05 24.1 0.7 3.1 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CblD PF07434.11 ORY91255.1 - 0.078 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator Homeodomain PF00046.29 ORY91256.1 - 2e-20 72.4 1.0 4e-20 71.4 1.0 1.5 1 0 0 1 1 1 1 Homeodomain Ribosomal_S5 PF00333.20 ORY91258.1 - 7.6e-30 102.7 2.1 1.3e-29 101.9 1.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORY91258.1 - 9.7e-25 85.8 0.1 1.6e-24 85.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORY91258.1 - 0.26 11.9 10.6 0.57 10.8 10.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RNA_pol_L_2 PF13656.6 ORY91259.1 - 6.7e-31 105.9 0.0 7.9e-31 105.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORY91259.1 - 7.2e-13 47.8 0.0 9.2e-13 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain OST3_OST6 PF04756.13 ORY91260.1 - 8.6e-103 343.7 0.1 1e-102 343.4 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 ORY91260.1 - 0.00035 20.5 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin MerC PF03203.14 ORY91260.1 - 1.3 9.5 8.0 2.3 8.7 1.6 3.0 3 0 0 3 3 3 0 MerC mercury resistance protein SNF2_N PF00176.23 ORY91261.1 - 1.3e-52 178.7 0.3 2.4e-52 177.8 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY91261.1 - 8.7e-12 45.4 0.1 2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORY91261.1 - 3.3e-09 36.4 12.5 6.1e-09 35.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY91261.1 - 4.4e-08 32.8 15.7 8.4e-08 31.9 15.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY91261.1 - 7.6e-08 32.6 15.6 1.5e-07 31.6 15.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY91261.1 - 2.7e-05 23.9 14.4 5e-05 23.1 14.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY91261.1 - 6.3e-05 22.9 11.8 0.00013 21.9 11.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY91261.1 - 0.00012 21.9 12.5 0.00023 21.0 12.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY91261.1 - 0.00029 21.1 12.6 0.00066 19.9 12.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY91261.1 - 0.00038 20.4 15.2 0.00067 19.6 15.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain KxDL PF10241.9 ORY91261.1 - 0.0056 16.9 0.9 0.49 10.7 0.1 3.1 2 0 0 2 2 2 1 Uncharacterized conserved protein WW PF00397.26 ORY91261.1 - 0.0076 16.3 0.2 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 WW domain ResIII PF04851.15 ORY91261.1 - 0.0083 16.1 0.2 0.05 13.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Zn_ribbon_17 PF17120.5 ORY91261.1 - 0.052 13.2 11.5 0.1 12.2 11.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FAM92 PF06730.11 ORY91261.1 - 0.064 12.7 5.4 0.021 14.2 1.1 2.3 2 0 0 2 2 2 0 FAM92 protein DUF3069 PF11269.8 ORY91261.1 - 0.086 13.1 0.1 0.59 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) PspA_IM30 PF04012.12 ORY91261.1 - 0.82 9.2 9.0 1.1 8.8 2.3 3.5 3 1 1 4 4 4 0 PspA/IM30 family zf-C3HC4_4 PF15227.6 ORY91261.1 - 1.8 8.8 13.0 3.3 7.9 13.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 ORY91261.1 - 2.6 8.3 11.0 9.4 6.5 11.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.6 ORY91261.1 - 3.8 7.7 8.0 3.4 7.9 3.8 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger Acetyltransf_1 PF00583.25 ORY91262.1 - 3.8e-11 43.3 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY91262.1 - 7.4e-10 38.9 0.0 1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY91262.1 - 1.6e-06 28.4 0.0 2.4e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY91262.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 ORY91262.1 - 0.036 14.7 0.0 0.047 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LRR_8 PF13855.6 ORY91263.1 - 0.016 14.9 0.5 33 4.3 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 ORY91263.1 - 0.027 14.4 0.0 0.082 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like L31 PF09784.9 ORY91265.1 - 6.7e-39 132.4 0.1 7.5e-39 132.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF2607 PF10795.9 ORY91265.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) UPF0029 PF01205.19 ORY91266.1 - 6e-35 119.8 0.1 1.2e-34 118.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 ORY91266.1 - 1.7e-14 54.0 0.1 3.3e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 RWD domain CRC_subunit PF08624.10 ORY91267.1 - 1e-44 152.2 0.0 1.6e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 ORY91267.1 - 1.8e-21 75.7 42.6 4.6e-09 36.0 13.5 3.8 2 1 1 3 3 3 3 PHD-finger C1_1 PF00130.22 ORY91267.1 - 0.021 14.7 1.5 0.021 14.7 1.5 4.5 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Requiem_N PF14051.6 ORY91267.1 - 0.092 13.0 0.1 0.31 11.3 0.1 1.9 1 1 0 1 1 1 0 N-terminal domain of DPF2/REQ. ASH PF15780.5 ORY91269.1 - 7e-17 61.4 2.5 0.077 13.2 0.0 10.7 11 1 0 11 11 11 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 ORY91269.1 - 5.8e-09 36.1 5.6 0.042 14.1 0.0 8.4 7 1 1 8 8 8 2 Transmembrane protein 131-like DUF1573 PF07610.11 ORY91269.1 - 1.5e-08 34.6 0.3 4.4 7.4 0.0 8.4 9 1 0 9 9 9 2 Protein of unknown function (DUF1573) fn3_5 PF06280.12 ORY91269.1 - 1.1e-05 26.1 0.2 0.16 12.6 0.0 6.5 7 0 0 7 7 7 1 Fn3-like domain PapD-like PF14874.6 ORY91269.1 - 1.1e-05 25.5 0.6 17 5.6 0.0 6.5 7 0 0 7 7 7 1 Flagellar-associated PapD-like Transglut_C PF00927.22 ORY91269.1 - 0.0024 18.0 0.7 3.4 7.9 0.0 4.8 4 1 0 4 4 4 1 Transglutaminase family, C-terminal ig like domain DUF1090 PF06476.12 ORY91269.1 - 0.074 13.2 5.0 0.17 12.0 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF916 PF06030.12 ORY91269.1 - 0.088 12.9 0.0 2.9 8.0 0.0 3.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) NPCBM_assoc PF10633.9 ORY91269.1 - 0.11 12.8 0.0 0.47 10.7 0.0 2.1 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase ATP-synt_ab PF00006.25 ORY91270.1 - 2.7e-64 216.8 0.4 1.4e-63 214.4 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY91270.1 - 1.8e-24 86.0 3.2 3.4e-24 85.2 2.3 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NACHT PF05729.12 ORY91270.1 - 0.011 15.6 0.1 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 ORY91270.1 - 0.013 14.8 1.0 0.016 14.4 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 ORY91270.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ORY91270.1 - 0.024 15.0 0.1 0.11 12.9 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORY91270.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 ORY91270.1 - 0.036 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.29 ORY91270.1 - 0.05 14.0 0.0 0.46 10.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY91270.1 - 0.077 13.3 0.1 1 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 ORY91270.1 - 0.078 13.3 0.5 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY91270.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T3SS_ATPase_C PF18269.1 ORY91270.1 - 0.14 12.0 0.3 0.92 9.4 0.3 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Chitin_synth_1 PF01644.17 ORY91271.1 - 1.9e-80 268.6 0.1 1.3e-79 265.8 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY91271.1 - 1.9e-29 102.7 0.0 4.1e-22 78.5 0.0 2.8 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY91271.1 - 2.7e-28 97.7 0.4 8.2e-28 96.2 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY91271.1 - 4.9e-05 23.3 12.3 4.9e-05 23.3 12.3 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cohesin_load PF10345.9 ORY91271.1 - 0.24 9.8 0.1 0.4 9.1 0.1 1.2 1 0 0 1 1 1 0 Cohesin loading factor DUF4064 PF13273.6 ORY91271.1 - 0.81 10.0 7.4 0.2 12.0 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4149 PF13664.6 ORY91271.1 - 5.1 7.5 12.4 9.8 6.6 2.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Ribosomal_L11_N PF03946.14 ORY91272.1 - 9.2e-23 79.9 0.1 2.1e-22 78.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY91272.1 - 8e-19 67.9 0.1 1.2e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF2462 PF09495.10 ORY91273.1 - 8.7e-20 71.2 16.8 8.7e-20 71.2 16.8 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) TPR_MLP1_2 PF07926.12 ORY91273.1 - 0.035 14.2 4.4 0.04 14.0 4.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Trehalase PF01204.18 ORY91274.1 - 3.4e-125 418.8 11.5 4.6e-114 382.1 4.4 1.9 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 ORY91274.1 - 0.0014 17.6 2.4 0.0045 16.0 2.4 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Methyltransf_11 PF08241.12 ORY91275.1 - 8.7e-15 55.2 0.1 2.3e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY91275.1 - 9.1e-13 48.7 0.0 2.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY91275.1 - 2.4e-11 44.2 0.0 5.5e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY91275.1 - 5.3e-11 42.6 0.0 7.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY91275.1 - 6.2e-08 32.6 0.0 9.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY91275.1 - 8.9e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY91275.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 ORY91275.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase DOT1 PF08123.13 ORY91275.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 ORY91275.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PLDc PF00614.22 ORY91277.1 - 3.2e-18 65.1 1.8 5e-11 42.3 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORY91277.1 - 6.1e-15 55.3 0.4 1.7e-05 24.8 0.0 3.6 4 0 0 4 4 4 3 PLD-like domain PX PF00787.24 ORY91277.1 - 1.1e-07 31.8 0.0 2.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 PX domain PH PF00169.29 ORY91277.1 - 0.11 13.0 0.2 0.3 11.6 0.2 1.8 1 0 0 1 1 1 0 PH domain RCDG1 PF15725.5 ORY91278.1 - 1.5 9.3 10.1 0.47 10.9 0.8 2.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF1218 PF06749.12 ORY91278.1 - 2.6 8.6 10.4 0.97 10.0 7.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) Acetyltransf_1 PF00583.25 ORY91279.1 - 9.8e-14 51.6 0.2 1.2e-13 51.3 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY91279.1 - 2.7e-08 34.1 0.1 4e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY91279.1 - 2.4e-07 30.8 0.2 3.3e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sec63 PF02889.16 ORY91279.1 - 0.049 12.8 0.2 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 Sec63 Brl domain BTB_2 PF02214.22 ORY91280.1 - 7e-21 74.4 0.5 1.6e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain NusB PF01029.18 ORY91280.1 - 0.021 15.1 1.5 0.039 14.2 0.2 2.0 3 0 0 3 3 3 0 NusB family AbiH PF14253.6 ORY91280.1 - 0.047 13.6 0.6 0.062 13.2 0.6 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH RhoGAP PF00620.27 ORY91281.1 - 1.6e-28 99.5 0.0 4.4e-28 98.0 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 ORY91281.1 - 2.9e-25 88.9 0.2 1e-24 87.1 0.1 2.1 2 0 0 2 2 2 1 MyTH4 domain CNH PF00780.22 ORY91282.1 - 4.2e-51 174.2 0.1 6.2e-51 173.6 0.1 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY91282.1 - 1.3e-33 116.7 1.3 2e-33 116.1 0.6 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 ORY91282.1 - 1.9e-18 66.9 0.0 3.9e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY91282.1 - 0.00097 19.6 0.0 0.0039 17.7 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_16 PF17838.1 ORY91282.1 - 0.03 14.2 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 PH domain MIT PF04212.18 ORY91283.1 - 7.1e-09 35.6 0.2 2.2e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF2379 PF09543.10 ORY91283.1 - 5.7 7.2 7.7 1.1 9.5 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) Myb_DNA-binding PF00249.31 ORY91285.1 - 0.0038 17.4 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY91285.1 - 0.027 14.4 2.7 0.087 12.7 0.1 2.6 2 0 0 2 2 2 0 Myb DNA-binding like DUF1296 PF06972.11 ORY91285.1 - 0.68 10.1 0.1 0.68 10.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) TFIIS_M PF07500.14 ORY91286.1 - 6.3e-27 94.3 0.2 1.2e-26 93.4 0.0 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 ORY91286.1 - 2.4e-19 68.9 7.3 3.6e-19 68.3 7.3 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 ORY91286.1 - 9e-11 41.6 1.8 2.3e-10 40.3 1.8 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain T3SS_basalb_I PF17001.5 ORY91286.1 - 0.0056 17.3 0.7 0.22 12.1 1.0 2.5 2 0 0 2 2 2 1 Type III secretion basal body protein I, YscI, HrpB, PscI zf-C4H2 PF10146.9 ORY91286.1 - 0.28 11.4 4.8 0.13 12.5 2.5 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein DUF4551 PF15087.6 ORY91286.1 - 0.53 9.1 2.3 0.76 8.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sad1_UNC PF07738.13 ORY91287.1 - 0.0003 20.8 0.0 0.00046 20.2 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Na_H_Exchanger PF00999.21 ORY91290.1 - 8.3e-57 192.7 21.3 1e-56 192.4 21.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY91290.1 - 0.052 13.6 0.7 0.052 13.6 0.7 3.2 3 1 1 4 4 4 0 YrhC-like protein Phage_holin_3_3 PF16083.5 ORY91290.1 - 0.16 12.1 0.2 0.16 12.1 0.2 4.0 5 0 0 5 5 5 0 LydA holin phage, holin superfamily III V_ATPase_I PF01496.19 ORY91290.1 - 2.1 6.1 6.9 0.26 9.2 2.1 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PepSY_TM PF03929.16 ORY91290.1 - 3.6 7.2 9.2 0.07 12.8 1.4 2.0 2 0 0 2 2 2 0 PepSY-associated TM region bZIP_2 PF07716.15 ORY91291.1 - 1.5e-08 34.6 11.1 4.5e-08 33.0 11.1 1.8 1 0 0 1 1 1 1 Basic region leucine zipper BSP_II PF05432.11 ORY91291.1 - 0.011 15.4 11.7 0.016 14.9 11.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) bZIP_1 PF00170.21 ORY91291.1 - 0.017 15.2 6.6 0.043 13.9 6.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor Macoilin PF09726.9 ORY91291.1 - 0.04 12.5 6.3 0.05 12.2 6.3 1.1 1 0 0 1 1 1 0 Macoilin family XhlA PF10779.9 ORY91291.1 - 0.066 13.4 0.9 0.16 12.2 0.9 1.6 1 0 0 1 1 1 0 Haemolysin XhlA HeLo PF14479.6 ORY91291.1 - 0.26 11.1 5.3 0.39 10.5 5.3 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Zip PF02535.22 ORY91291.1 - 2.7 7.1 4.1 3.9 6.6 4.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-HIT PF04438.16 ORY91292.1 - 2.5e-09 36.8 13.0 3.4e-09 36.4 13.0 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 ORY91292.1 - 0.02 15.0 14.0 0.031 14.4 14.0 1.3 1 0 0 1 1 1 0 MYND finger Acetyltransf_1 PF00583.25 ORY91293.1 - 1.3e-12 47.9 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY91293.1 - 5.3e-08 33.2 0.2 2.3e-07 31.1 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY91293.1 - 2.1e-07 30.9 0.0 4.9e-07 29.7 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY91293.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY91293.1 - 0.00013 22.0 0.2 0.00026 21.1 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY91293.1 - 0.001 19.2 0.1 0.0014 18.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 ORY91294.1 - 6.9e-50 169.8 0.1 6.2e-49 166.7 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91294.1 - 2.9e-20 72.6 0.0 9.5e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY91294.1 - 2.9e-05 24.1 1.1 0.00055 19.9 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY91294.1 - 0.15 11.7 0.1 0.36 10.4 0.1 1.7 1 0 0 1 1 1 0 RIO1 family RSN1_7TM PF02714.15 ORY91295.1 - 1.4e-82 277.1 24.2 1.4e-82 277.1 24.2 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY91295.1 - 6.1e-32 111.3 0.0 1.3e-31 110.2 0.0 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY91295.1 - 1.5e-27 96.3 2.2 1.5e-27 96.3 2.2 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport YL1 PF05764.13 ORY91295.1 - 0.1 12.7 3.1 0.15 12.1 3.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Bystin PF05291.11 ORY91296.1 - 3e-73 246.7 0.0 3.8e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Bystin Motile_Sperm PF00635.26 ORY91297.1 - 1.1e-24 86.4 0.5 3.1e-24 84.9 0.2 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain DUF5042 PF16445.5 ORY91297.1 - 0.002 16.6 0.0 0.23 9.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5042) F-box PF00646.33 ORY91301.1 - 4.8e-07 29.5 0.1 8.8e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY91301.1 - 0.0001 22.1 0.0 0.00025 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like LON_substr_bdg PF02190.16 ORY91303.1 - 2.1e-11 44.1 0.0 9.1e-11 42.0 0.0 2.0 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 ORY91303.1 - 1.7e-08 34.5 21.2 0.00014 21.9 4.9 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY91303.1 - 2e-05 24.3 7.9 0.0013 18.5 1.9 2.4 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 ORY91303.1 - 0.00012 22.2 15.3 0.0027 17.8 4.9 2.5 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 ORY91303.1 - 0.00026 20.9 21.4 0.013 15.5 8.1 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 ORY91303.1 - 0.0024 17.8 21.9 0.15 12.1 4.2 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY91303.1 - 0.0046 16.8 21.8 0.007 16.2 9.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY91303.1 - 0.0052 16.6 25.0 0.014 15.3 10.6 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY91303.1 - 0.036 13.9 23.4 0.055 13.3 1.2 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF728 PF05304.12 ORY91303.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Zn_Tnp_IS91 PF14319.6 ORY91303.1 - 9.1 6.4 14.3 1.8 8.6 1.1 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain BUD22 PF09073.10 ORY91304.1 - 2.2e-18 66.9 60.0 2.3e-10 40.4 21.0 4.3 1 1 2 3 3 3 3 BUD22 VHS PF00790.19 ORY91305.1 - 2e-42 144.4 0.7 8.7e-41 139.1 0.0 2.6 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 ORY91305.1 - 4.1e-22 78.6 0.1 4.1e-22 78.6 0.1 2.5 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 ORY91305.1 - 3.8e-16 59.1 7.5 3.8e-16 59.1 7.5 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 ORY91305.1 - 7.2e-05 22.3 0.0 0.0003 20.4 0.0 2.1 1 0 0 1 1 1 1 GGA N-GAT domain TnpW PF14202.6 ORY91305.1 - 0.15 12.0 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Transposon-encoded protein TnpW SPOUT_MTase_2 PF14419.6 ORY91305.1 - 0.15 11.4 0.3 0.31 10.4 0.3 1.5 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP PH PF00169.29 ORY91306.1 - 2.3e-19 69.8 0.3 6.9e-19 68.3 0.3 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 ORY91306.1 - 2.1e-18 66.2 0.0 8.1e-18 64.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 ORY91306.1 - 1e-14 54.1 0.0 3e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 ORY91306.1 - 5e-14 52.5 0.0 2.9e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 ORY91306.1 - 3.3e-12 45.8 0.1 1.2e-11 44.1 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY91306.1 - 1.5e-10 40.6 0.0 3.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 ORY91306.1 - 2.1e-05 24.9 4.9 0.00074 19.9 4.9 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain CH PF00307.31 ORY91306.1 - 0.00023 21.3 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_8 PF15409.6 ORY91306.1 - 0.02 15.1 0.5 0.044 14.1 0.5 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain SAM_Ste50p PF09235.10 ORY91306.1 - 0.023 14.9 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Pkinase PF00069.25 ORY91307.1 - 2e-66 224.1 0.0 2.5e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91307.1 - 5.8e-33 114.3 0.0 8.2e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 ORY91307.1 - 5.7e-24 84.2 0.0 1.4e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORY91307.1 - 9.4e-07 28.4 0.0 5.2e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY91307.1 - 0.0031 16.5 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY91307.1 - 0.0049 16.8 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY91307.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY91307.1 - 0.025 13.4 0.0 0.058 12.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L31 PF01197.18 ORY91307.1 - 0.1 12.8 0.9 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L31 Seadorna_VP7 PF07387.11 ORY91307.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YukC PF10140.9 ORY91307.1 - 0.17 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pkinase_Tyr PF07714.17 ORY91308.1 - 1.7e-24 86.5 0.0 2.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY91308.1 - 6e-23 81.5 0.0 9.3e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ArfGap PF01412.18 ORY91311.1 - 5.1e-44 149.1 1.3 8.4e-44 148.4 1.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Haem_degrading PF03928.14 ORY91312.1 - 6.5e-31 106.9 0.0 7.7e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading DAGK_cat PF00781.24 ORY91313.1 - 5.2e-27 94.0 0.0 8.4e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Snf7 PF03357.21 ORY91314.1 - 1.5e-34 119.1 12.3 1.5e-34 119.1 12.3 2.0 2 0 0 2 2 2 2 Snf7 DUF4763 PF15960.5 ORY91314.1 - 0.034 13.4 0.8 0.035 13.4 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) zf-CCHC PF00098.23 ORY91316.1 - 4.6e-07 29.6 3.4 6.8e-07 29.1 3.4 1.2 1 0 0 1 1 1 1 Zinc knuckle Abhydrolase_9_N PF15420.6 ORY91316.1 - 0.057 13.4 0.8 0.09 12.8 0.8 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus zf-CCHC_6 PF15288.6 ORY91316.1 - 0.076 12.9 1.2 0.15 11.9 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 ORY91316.1 - 0.1 12.4 1.9 0.17 11.6 1.9 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ORY91316.1 - 0.11 12.4 0.7 0.18 11.6 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle THRAP3_BCLAF1 PF15440.6 ORY91316.1 - 7.6 5.4 7.2 11 4.9 7.2 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family RRM_1 PF00076.22 ORY91317.1 - 9.9e-10 38.1 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 ORY91318.1 - 2.4e-09 36.9 0.4 1.1e-08 34.8 0.4 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY91318.1 - 0.00064 19.5 0.1 0.0035 17.2 0.1 2.4 1 0 0 1 1 1 1 F-box domain TauD PF02668.16 ORY91319.1 - 7.5e-36 124.3 0.1 1.3e-35 123.5 0.1 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORY91319.1 - 9.6e-20 71.0 1.0 2e-19 70.0 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORY91319.1 - 0.00033 19.9 0.1 0.034 13.3 0.0 2.2 2 0 0 2 2 2 2 CsiD Pantoate_transf PF02548.15 ORY91321.1 - 1e-101 339.7 0.3 1.2e-101 339.5 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 ORY91321.1 - 4.2e-06 26.4 0.2 1.4e-05 24.7 0.2 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Poly_export PF02563.16 ORY91321.1 - 0.11 12.7 0.1 0.97 9.7 0.0 2.4 3 0 0 3 3 3 0 Polysaccharide biosynthesis/export protein ABC_membrane PF00664.23 ORY91324.1 - 1.2e-50 172.8 35.5 2.3e-30 106.2 12.5 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY91324.1 - 7.1e-48 162.6 0.0 5.2e-28 98.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY91324.1 - 6.2e-07 29.1 5.3 0.0039 16.7 1.1 4.0 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY91324.1 - 2.2e-05 24.1 0.4 0.19 11.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 ORY91324.1 - 3.4e-05 24.0 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_25 PF13481.6 ORY91324.1 - 0.0004 20.0 0.0 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY91324.1 - 0.00096 18.3 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY91324.1 - 0.0011 18.4 0.5 0.37 10.1 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 ORY91324.1 - 0.002 18.4 0.4 2 8.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 ORY91324.1 - 0.0041 17.2 1.2 0.4 10.7 0.0 3.1 3 0 0 3 3 3 1 Dynamin family ATPase PF06745.13 ORY91324.1 - 0.011 15.0 0.1 5.1 6.4 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 ORY91324.1 - 0.031 14.7 0.0 8.6 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 ORY91324.1 - 0.031 14.8 6.6 0.11 13.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 ORY91324.1 - 0.036 13.0 0.0 3.2 6.6 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 ORY91324.1 - 0.042 13.7 0.4 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 ORY91324.1 - 0.043 13.9 0.1 6.8 6.8 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 ORY91324.1 - 0.066 12.7 0.3 11 5.5 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORY91324.1 - 0.11 12.2 0.0 22 4.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 ORY91324.1 - 0.18 11.5 0.3 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY91324.1 - 0.19 11.0 0.1 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.12 ORY91324.1 - 0.22 11.0 0.7 11 5.4 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_21 PF13304.6 ORY91324.1 - 0.39 10.5 3.5 36 4.0 0.0 3.5 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 ORY91324.1 - 1.5 8.6 3.7 1 9.1 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 ORY91324.1 - 4 7.0 5.2 12 5.5 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain CotH PF08757.11 ORY91325.1 - 2.2e-44 152.3 2.5 3.7e-44 151.5 2.5 1.3 1 0 0 1 1 1 1 CotH kinase protein RNase_T PF00929.24 ORY91325.1 - 0.01 16.4 0.1 0.026 15.1 0.1 1.7 1 0 0 1 1 1 0 Exonuclease DASH_Duo1 PF08651.10 ORY91326.1 - 9.9e-19 66.9 0.5 9.9e-19 66.9 0.5 1.7 2 0 0 2 2 2 1 DASH complex subunit Duo1 FUSC PF04632.12 ORY91326.1 - 9.2 4.7 8.4 11 4.4 8.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DcuC PF03606.15 ORY91327.1 - 4.8e-05 22.0 0.2 4.8e-05 22.0 0.2 2.0 2 0 0 2 2 2 1 C4-dicarboxylate anaerobic carrier Zip PF02535.22 ORY91327.1 - 0.0031 16.8 3.5 4.3 6.5 0.0 3.6 3 1 1 4 4 4 2 ZIP Zinc transporter SARAF PF06682.12 ORY91327.1 - 0.11 12.1 0.1 0.82 9.3 0.0 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Tmemb_14 PF03647.13 ORY91327.1 - 0.36 11.6 4.2 4.6 8.0 0.5 3.6 3 1 0 3 3 3 0 Transmembrane proteins 14C CcmH PF03918.14 ORY91327.1 - 0.45 9.8 2.3 3.8 6.8 0.0 3.5 2 1 0 3 3 3 0 Cytochrome C biogenesis protein Wzy_C_2 PF11846.8 ORY91327.1 - 0.62 10.0 11.6 36 4.2 3.9 3.9 3 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal MRAP PF15183.6 ORY91327.1 - 3.2 7.8 9.8 0.66 10.0 0.2 4.3 5 0 0 5 5 5 0 Melanocortin-2 receptor accessory protein family DUF3139 PF11337.8 ORY91327.1 - 8.6 7.1 7.5 4.4 8.0 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) MFS_1 PF07690.16 ORY91328.1 - 1.7e-47 162.0 41.9 1.7e-47 162.0 41.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY91328.1 - 3.9e-14 52.0 28.8 7e-13 47.9 28.8 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY91328.1 - 1.4e-10 40.7 13.8 1.4e-10 40.7 13.8 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORY91328.1 - 0.00016 20.6 5.2 0.00016 20.6 5.2 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF2157 PF09925.9 ORY91328.1 - 5.2 6.9 13.7 0.25 11.1 3.8 3.5 2 2 0 2 2 2 0 Predicted membrane protein (DUF2157) CRF PF00473.17 ORY91329.1 - 0.095 12.8 1.0 0.15 12.1 1.0 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor family DUF5104 PF17117.5 ORY91329.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) PUF PF00806.19 ORY91330.1 - 1.5e-44 147.2 0.0 7.1e-07 28.6 0.0 8.6 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat DUF3584 PF12128.8 ORY91330.1 - 0.013 13.1 5.7 0.02 12.5 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 ORY91330.1 - 0.036 14.2 5.5 0.066 13.3 5.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Prominin PF05478.11 ORY91330.1 - 0.25 9.3 2.7 0.4 8.6 2.7 1.2 1 0 0 1 1 1 0 Prominin FUSC_2 PF13515.6 ORY91331.1 - 2.2e-17 63.3 32.7 2.3e-17 63.3 14.4 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 ORY91331.1 - 9.6e-16 57.9 18.2 1.5e-11 44.0 0.2 4.2 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 ORY91331.1 - 1.3e-14 54.7 0.1 2.5e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ORY91331.1 - 2.7e-12 46.1 16.2 2.7e-12 46.1 16.2 3.4 5 0 0 5 5 5 1 Fusaric acid resistance protein family ALMT PF11744.8 ORY91331.1 - 5.3e-12 45.3 5.0 5.3e-12 45.3 5.0 2.8 4 0 0 4 4 4 1 Aluminium activated malate transporter ArAE_1 PF06081.11 ORY91331.1 - 0.00022 21.4 5.0 0.00022 21.4 5.0 2.9 3 0 0 3 3 3 1 Aromatic acid exporter family member 1 FUSC-like PF12805.7 ORY91331.1 - 0.0025 16.9 0.9 0.0064 15.6 0.9 1.7 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS Wzy_C PF04932.15 ORY91331.1 - 0.036 13.7 1.0 0.19 11.4 0.2 2.3 2 0 0 2 2 2 0 O-Antigen ligase PDGF_N PF04692.13 ORY91331.1 - 1.1 10.0 13.8 0.035 14.9 3.8 3.3 3 0 0 3 3 3 0 Platelet-derived growth factor, N terminal region DUF2645 PF10840.8 ORY91331.1 - 8.4 7.1 8.0 24 5.7 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2645) RNA_pol_Rpb2_6 PF00562.28 ORY91332.1 - 4.2e-131 437.6 0.1 6.8e-131 436.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY91332.1 - 9.7e-67 224.4 0.1 1.4e-66 223.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 ORY91332.1 - 1.5e-48 165.0 0.1 6.4e-48 162.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORY91332.1 - 8.5e-35 119.0 0.1 3.8e-34 117.0 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 ORY91332.1 - 5.9e-25 87.2 0.0 1.3e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 ORY91332.1 - 6.7e-24 83.9 0.1 1.7e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 ORY91332.1 - 3.5e-22 78.7 0.2 1.3e-21 76.9 0.2 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pkinase PF00069.25 ORY91333.1 - 3.2e-27 95.6 0.0 4.2e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91333.1 - 4.8e-14 52.3 0.0 6.2e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY91333.1 - 1.3e-10 40.7 0.0 1.9e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY91333.1 - 2.6e-05 24.3 0.1 0.0037 17.2 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY91333.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY91335.1 - 3.4e-55 187.3 0.0 3.8e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91335.1 - 4.9e-29 101.4 0.0 6.2e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY91335.1 - 1.1e-06 28.2 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY91335.1 - 0.00067 19.7 0.6 0.0069 16.3 0.2 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY91335.1 - 0.0029 16.6 0.1 0.0038 16.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY91335.1 - 0.0043 16.7 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY91335.1 - 0.029 13.7 0.2 0.038 13.3 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY91335.1 - 0.069 11.9 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PIG-Y PF15159.6 ORY91337.1 - 1.3e-20 74.1 4.5 1.7e-20 73.7 4.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y RRM_1 PF00076.22 ORY91338.1 - 3.4e-53 177.3 0.0 7.1e-18 64.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY91338.1 - 1.1e-05 25.4 0.8 0.019 15.1 0.1 3.6 3 2 0 3 3 3 2 Limkain b1 RRM_5 PF13893.6 ORY91338.1 - 0.00038 20.1 0.0 0.089 12.4 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY91338.1 - 0.0013 18.6 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif BRAP2 PF07576.12 ORY91338.1 - 0.0076 16.4 0.0 0.83 9.9 0.0 2.4 2 0 0 2 2 2 1 BRCA1-associated protein 2 RRM_Rrp7 PF17799.1 ORY91338.1 - 0.012 15.4 0.0 8.9 6.1 0.0 3.0 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_9 PF18444.1 ORY91338.1 - 0.025 14.4 0.0 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DbpA PF03880.15 ORY91338.1 - 0.074 13.0 0.0 7.9 6.6 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain Presenilin PF01080.17 ORY91338.1 - 1 8.1 8.4 1.6 7.4 8.4 1.4 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 ORY91338.1 - 2 8.2 6.2 3.8 7.2 6.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.9 ORY91338.1 - 8.9 4.7 14.5 11 4.4 14.5 1.1 1 0 0 1 1 1 0 Macoilin family zf-C2H2 PF00096.26 ORY91339.1 - 1.6e-07 31.3 36.0 0.00022 21.5 1.3 5.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY91339.1 - 2.9e-05 24.5 33.7 0.00026 21.6 1.1 5.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY91339.1 - 4.1e-05 23.8 15.8 0.03 14.7 2.1 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY91339.1 - 0.001 19.0 0.2 0.001 19.0 0.2 3.9 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY91339.1 - 0.013 15.8 0.3 0.013 15.8 0.3 3.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY91339.1 - 0.013 15.7 15.0 0.053 13.8 0.3 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 ORY91339.1 - 0.028 14.1 0.9 0.077 12.7 0.2 2.2 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_aberr PF17017.5 ORY91339.1 - 0.11 12.7 0.3 0.11 12.7 0.3 3.7 2 1 1 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 ORY91339.1 - 0.12 12.8 7.6 7.1 7.2 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type TonB_N PF16031.5 ORY91339.1 - 0.33 11.5 10.3 0.58 10.7 10.3 1.3 1 0 0 1 1 1 0 TonB polyproline region C1_1 PF00130.22 ORY91339.1 - 0.39 10.6 5.5 0.1 12.5 2.1 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.6 ORY91339.1 - 1 9.2 10.9 0.1 12.4 0.9 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 ORY91339.1 - 9.6 6.3 9.2 4.8 7.3 0.1 3.5 3 0 0 3 3 3 0 BED zinc finger zf-C2H2 PF00096.26 ORY91340.1 - 0.00048 20.4 16.7 0.032 14.7 4.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY91340.1 - 0.0014 19.2 2.7 0.2 12.3 0.4 2.5 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORY91340.1 - 0.01 16.2 7.1 0.062 13.8 3.9 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY91340.1 - 0.013 16.3 14.5 2.3 9.3 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY91340.1 - 0.048 13.4 5.3 0.97 9.3 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zn_clus PF00172.18 ORY91341.1 - 0.0027 17.8 12.2 0.0043 17.1 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 ORY91342.1 - 2.6e-39 135.8 0.2 3e-39 135.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY91342.1 - 0.00089 19.4 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY91342.1 - 0.00089 18.6 0.1 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY91342.1 - 0.004 16.4 0.1 0.009 15.3 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ORY91342.1 - 0.015 14.4 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY91342.1 - 0.026 14.1 1.4 0.071 12.7 0.7 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 ORY91342.1 - 0.036 14.6 0.4 0.11 13.1 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ORY91342.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ORY91342.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PHD PF00628.29 ORY91344.1 - 1.6e-09 37.5 9.6 3.5e-09 36.4 9.6 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 ORY91344.1 - 4e-07 30.6 0.0 1.6e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 SET domain PHD_2 PF13831.6 ORY91344.1 - 0.00058 19.4 4.3 0.0011 18.4 4.3 1.5 1 0 0 1 1 1 1 PHD-finger Ribosomal_S7 PF00177.21 ORY91345.1 - 3.5e-37 127.3 1.0 4.5e-37 127.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-C2H2_4 PF13894.6 ORY91347.1 - 2e-06 28.1 24.9 0.13 13.2 0.4 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY91347.1 - 1.5e-05 25.2 27.9 0.08 13.4 0.5 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORY91347.1 - 0.00066 19.9 10.1 0.21 11.7 5.4 2.5 1 1 0 2 2 2 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 ORY91347.1 - 0.086 13.3 16.3 6.1 7.5 2.2 4.8 4 1 0 4 4 4 0 Zinc-finger double domain FBP_C PF16571.5 ORY91347.1 - 0.13 11.8 2.1 0.17 11.4 1.2 1.7 1 1 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Inositol_P PF00459.25 ORY91349.1 - 2.5e-56 191.2 1.0 5.9e-56 190.0 1.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family HypD PF01924.16 ORY91349.1 - 0.059 12.4 0.3 0.088 11.9 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family HTH_8 PF02954.19 ORY91349.1 - 0.29 10.9 2.0 0.6 10.0 0.0 2.5 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family Abhydrolase_2 PF02230.16 ORY91350.1 - 1e-57 195.5 0.0 1.1e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY91350.1 - 2.3e-09 36.9 0.6 4.1e-05 23.0 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 ORY91350.1 - 7e-07 29.0 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 ORY91350.1 - 3.6e-06 26.8 0.0 6.5e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 ORY91350.1 - 9.9e-05 22.1 0.7 0.19 11.4 0.0 3.2 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY91350.1 - 0.00014 21.4 0.2 0.001 18.6 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORY91350.1 - 0.00039 21.1 0.7 0.0031 18.1 0.3 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ORY91350.1 - 0.0019 18.1 0.1 1.4 8.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.8 ORY91350.1 - 0.0021 17.3 0.0 1 8.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) Abhydrolase_4 PF08386.10 ORY91350.1 - 0.04 14.0 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PE-PPE PF08237.11 ORY91350.1 - 0.15 11.6 0.0 0.62 9.6 0.0 1.8 2 0 0 2 2 2 0 PE-PPE domain SKA1 PF07160.12 ORY91351.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Pirin PF02678.16 ORY91352.1 - 1.6e-32 111.7 0.1 2.7e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORY91352.1 - 5.5e-29 100.6 0.0 1.6e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORY91352.1 - 0.032 13.9 0.8 0.094 12.4 0.5 1.9 2 0 0 2 2 2 0 Cupin domain Peptidase_M16_C PF05193.21 ORY91353.1 - 4.5e-32 111.5 0.1 8e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY91353.1 - 2.3e-26 92.6 0.1 5.6e-26 91.3 0.1 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) NDT80_PhoG PF05224.12 ORY91355.1 - 1.5e-38 132.9 1.5 2.2e-38 132.3 0.0 2.1 3 0 0 3 3 3 1 NDT80 / PhoG like DNA-binding family GAS2 PF02187.17 ORY91357.1 - 9.5e-11 41.6 0.1 2.7e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 ORY91357.1 - 6.8e-09 35.9 0.0 3.6e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY91357.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain DUF2673 PF10880.8 ORY91357.1 - 0.076 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DUF2570 PF10828.8 ORY91357.1 - 0.091 12.6 5.3 0.71 9.7 0.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) Spectrin PF00435.21 ORY91357.1 - 0.2 12.1 52.6 0.15 12.6 0.3 8.1 8 1 0 8 8 8 0 Spectrin repeat Flg_hook PF02120.16 ORY91357.1 - 2 8.4 7.8 43 4.1 1.0 4.4 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Seryl_tRNA_N PF02403.22 ORY91357.1 - 5.5 7.3 22.3 19 5.5 0.1 6.7 5 1 1 6 6 6 0 Seryl-tRNA synthetase N-terminal domain DUF1752 PF08550.10 ORY91358.1 - 6.8e-12 45.0 4.1 1.7e-11 43.7 4.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUIM_assoc PF16619.5 ORY91358.1 - 0.0077 16.3 1.2 0.0077 16.3 1.2 1.9 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 CYSTM PF12734.7 ORY91359.1 - 0.94 9.9 60.4 1.8e+04 -4.7 60.4 4.0 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 ORY91359.1 - 8 6.4 8.6 8 6.4 8.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TMCO5 PF14992.6 ORY91360.1 - 0.045 13.3 0.7 0.051 13.2 0.7 1.0 1 0 0 1 1 1 0 TMCO5 family Glyco_transf_49 PF13896.6 ORY91362.1 - 3.2e-27 95.8 4.0 4.1e-20 72.4 0.5 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan START PF01852.19 ORY91363.1 - 3.2e-12 46.3 0.1 4.8e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 START domain RabGAP-TBC PF00566.18 ORY91364.1 - 9.4e-54 182.3 2.6 9.6e-54 182.3 0.0 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Laminin_II PF06009.12 ORY91364.1 - 3.8 7.5 21.4 0.31 11.0 1.3 2.9 2 1 0 2 2 2 0 Laminin Domain II Velvet PF11754.8 ORY91365.1 - 1.6e-35 123.3 0.6 3.9e-35 122.0 0.6 1.5 1 1 0 1 1 1 1 Velvet factor tRNA-synt_2b PF00587.25 ORY91366.1 - 1.6e-36 126.0 0.0 3e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY91366.1 - 8.5e-19 67.5 0.1 2.2e-18 66.2 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 ORY91366.1 - 3.3e-15 55.9 0.0 2.2e-12 46.8 0.0 2.7 2 0 0 2 2 2 2 TGS domain tRNA_SAD PF07973.14 ORY91366.1 - 1.8e-10 40.7 0.0 4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Velvet PF11754.8 ORY91367.1 - 4.6e-72 243.0 8.7 4e-45 154.7 0.1 3.1 2 1 1 3 3 3 2 Velvet factor SPX PF03105.19 ORY91367.1 - 0.88 9.4 4.7 1 9.2 4.7 1.1 1 0 0 1 1 1 0 SPX domain CoA_transf_3 PF02515.17 ORY91368.1 - 1e-117 393.4 0.0 1.2e-117 393.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CAP_N PF01213.19 ORY91370.1 - 0.41 10.1 4.6 0.71 9.3 4.6 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DHBP_synthase PF00926.19 ORY91371.1 - 2e-83 278.7 0.0 2.3e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase FRG2 PF15315.6 ORY91373.1 - 3 8.0 20.9 3.6 7.8 20.9 1.0 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 USP7_ICP0_bdg PF12436.8 ORY91375.1 - 7.4e-08 32.0 1.0 9.4e-08 31.7 1.0 1.1 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 PBS_linker_poly PF00427.21 ORY91375.1 - 0.015 15.3 0.2 0.021 14.9 0.2 1.3 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF3549 PF12069.8 ORY91375.1 - 0.032 13.3 0.1 0.041 12.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Bud13 PF09736.9 ORY91375.1 - 0.049 14.0 0.1 0.075 13.4 0.1 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex UCH PF00443.29 ORY91376.1 - 2.9e-11 43.4 0.1 4.4e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY91376.1 - 0.0009 18.9 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2722 PF10846.8 ORY91377.1 - 1.1e-06 27.9 7.0 1.1e-06 27.9 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med15 PF09606.10 ORY91377.1 - 0.02 13.6 20.9 0.02 13.6 20.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nop53 PF07767.11 ORY91377.1 - 0.026 13.9 19.6 0.033 13.6 19.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.17 ORY91377.1 - 0.027 14.6 1.4 0.028 14.6 1.4 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 ORY91377.1 - 0.13 10.5 3.3 0.13 10.5 3.3 1.0 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.9 ORY91377.1 - 0.15 10.3 13.5 0.15 10.3 13.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 ORY91377.1 - 0.17 11.8 24.3 0.2 11.7 24.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 ORY91377.1 - 0.27 11.8 16.1 0.38 11.3 16.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4407 PF14362.6 ORY91377.1 - 0.51 9.6 10.5 0.65 9.3 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC14 PF08045.11 ORY91377.1 - 0.59 9.2 6.5 0.71 8.9 6.5 1.1 1 0 0 1 1 1 0 Cell division control protein 14, SIN component DUF1178 PF06676.11 ORY91377.1 - 0.68 10.3 12.8 0.99 9.8 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Ctr PF04145.15 ORY91377.1 - 0.73 10.4 2.2 0.86 10.2 2.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Allexi_40kDa PF05549.11 ORY91377.1 - 0.82 9.1 5.0 1 8.8 5.0 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4834 PF16118.5 ORY91377.1 - 1 10.4 11.7 1.6 9.8 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF913 PF06025.12 ORY91377.1 - 1.1 8.2 5.6 1.4 7.8 5.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ndc1_Nup PF09531.10 ORY91377.1 - 1.2 7.7 6.0 1.4 7.5 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 ORY91377.1 - 1.4 8.4 32.7 1.9 8.0 32.7 1.1 1 0 0 1 1 1 0 Spt20 family Pox_G7 PF05503.12 ORY91377.1 - 1.6 7.6 3.2 1.9 7.3 3.2 1.1 1 0 0 1 1 1 0 Poxvirus G7-like FlaG PF03646.15 ORY91377.1 - 1.6 9.0 15.8 2.3 8.5 15.8 1.2 1 0 0 1 1 1 0 FlaG protein D123 PF07065.14 ORY91377.1 - 1.7 7.7 9.4 2 7.5 9.4 1.1 1 0 0 1 1 1 0 D123 DUF3464 PF11947.8 ORY91377.1 - 2.3 7.9 10.3 3.4 7.4 10.3 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Suf PF05843.14 ORY91377.1 - 2.9 7.8 14.5 3.9 7.4 14.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MMR1 PF08505.10 ORY91377.1 - 3 8.1 16.1 3.8 7.7 16.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein AAT PF03417.16 ORY91377.1 - 4.2 7.0 9.0 5.8 6.5 9.0 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase EIIBC-GUT_N PF03612.14 ORY91377.1 - 4.6 6.9 9.8 5.6 6.7 9.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MTABC_N PF16185.5 ORY91377.1 - 5.7 6.4 4.5 7.2 6.0 4.5 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region HA2 PF04408.23 ORY91377.1 - 6.2 7.2 6.1 10 6.5 6.1 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) SpoIIP PF07454.11 ORY91377.1 - 6.9 6.0 11.0 8.3 5.8 11.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4228 PF14009.6 ORY91377.1 - 7.2 7.0 9.5 11 6.4 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) GTA_holin_3TM PF11351.8 ORY91377.1 - 7.4 7.1 10.6 12 6.5 10.6 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release OATP PF03137.20 ORY91377.1 - 9.3 4.4 7.3 12 4.0 7.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF775 PF05603.12 ORY91377.1 - 9.3 5.7 13.5 11 5.4 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) zf-C2H2_4 PF13894.6 ORY91378.1 - 2e-07 31.3 7.8 0.0034 18.1 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY91378.1 - 2e-07 31.1 8.8 0.00019 21.7 0.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY91378.1 - 5e-07 29.9 14.1 6.2e-06 26.4 0.3 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.12 ORY91378.1 - 0.00081 19.6 1.8 0.00093 19.4 1.8 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORY91378.1 - 0.0012 19.0 3.2 0.12 12.7 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY91378.1 - 0.0056 16.9 0.2 0.0056 16.9 0.2 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger OTCace PF00185.24 ORY91380.1 - 2.4e-52 177.1 0.0 3.8e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 ORY91380.1 - 2.4e-45 154.2 0.3 3.8e-45 153.5 0.3 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain FG-GAP PF01839.23 ORY91381.1 - 8.6e-05 22.6 0.2 0.00016 21.7 0.2 1.4 1 0 0 1 1 1 1 FG-GAP repeat BBS1 PF14779.6 ORY91381.1 - 0.005 16.3 0.0 1.6 8.1 0.0 2.1 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 1 VCBS PF13517.6 ORY91381.1 - 0.01 16.4 0.6 0.033 14.8 0.3 2.0 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 ORY91381.1 - 0.012 15.7 0.1 0.034 14.2 0.1 1.8 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 ORY91381.1 - 0.012 14.7 0.3 0.086 11.9 0.1 1.9 1 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 ORY91382.1 - 0.00068 19.7 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region 4HBT PF03061.22 ORY91383.1 - 0.0015 18.8 0.1 0.38 11.1 0.1 2.5 2 0 0 2 2 2 2 Thioesterase superfamily MFS_1 PF07690.16 ORY91384.1 - 1.5e-53 182.0 43.5 9.3e-51 172.8 43.2 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY91384.1 - 1.4e-15 56.8 18.7 1.4e-15 56.8 18.7 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY91384.1 - 2e-14 53.3 8.2 2e-14 53.3 8.2 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORY91384.1 - 0.00012 21.1 6.3 0.00012 21.1 6.3 2.9 2 1 0 2 2 2 1 MFS_1 like family PIRT PF15099.6 ORY91384.1 - 0.53 9.9 2.6 2.1 7.9 2.6 2.0 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Phage_holin_3_2 PF04550.12 ORY91384.1 - 2.3 8.8 15.7 10 6.8 7.0 3.2 2 0 0 2 2 2 0 Phage holin family 2 Homeodomain PF00046.29 ORY91385.1 - 2.3e-13 49.8 4.6 3.8e-13 49.1 4.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY91385.1 - 7.3e-05 22.6 1.1 7.3e-05 22.6 1.1 1.7 2 0 0 2 2 2 1 Homeobox KN domain PT PF04886.12 ORY91385.1 - 0.0053 16.3 1.3 0.015 14.8 1.3 1.7 1 0 0 1 1 1 1 PT repeat cNMP_binding PF00027.29 ORY91386.1 - 8.1e-42 141.2 0.0 1.2e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain F-box PF00646.33 ORY91386.1 - 1.8e-05 24.4 2.4 0.0013 18.6 0.4 3.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY91386.1 - 0.0015 18.4 1.1 0.69 9.8 0.2 2.7 2 0 0 2 2 2 2 F-box-like PPP1R35_C PF15503.6 ORY91386.1 - 0.022 14.6 0.5 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus F-box_4 PF15966.5 ORY91386.1 - 0.16 11.9 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 F-box Aldedh PF00171.22 ORY91387.1 - 6.4e-90 301.9 0.0 7.4e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family O-FucT PF10250.9 ORY91388.1 - 2e-11 44.2 3.4 1.6e-09 37.9 3.4 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CFTR_R PF14396.6 ORY91388.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain WD40 PF00400.32 ORY91389.1 - 2.7e-21 75.5 6.1 0.02 15.7 0.1 9.3 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY91389.1 - 4.9e-06 26.8 0.0 1.4 9.2 0.0 6.4 4 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORY91390.1 - 2.4e-05 24.1 0.1 4.4e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 F-box domain PCI PF01399.27 ORY91391.1 - 2.2e-11 44.2 0.5 8.2e-11 42.3 0.1 2.1 2 0 0 2 2 2 1 PCI domain Aida_N PF08910.10 ORY91391.1 - 0.12 12.8 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 Aida N-terminus Pkinase PF00069.25 ORY91392.1 - 8.3e-51 172.9 0.0 1.2e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91392.1 - 1.1e-32 113.3 0.0 1.6e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY91392.1 - 0.00062 19.2 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY91392.1 - 0.01 15.8 0.6 0.019 14.9 0.6 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY91392.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PH PF00169.29 ORY91393.1 - 0.0065 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 PH domain MIT PF04212.18 ORY91394.1 - 0.34 11.0 2.6 0.76 9.9 0.4 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain tRNA-synt_1 PF00133.22 ORY91395.1 - 3.2e-229 762.2 0.3 6.5e-229 761.2 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY91395.1 - 2.8e-25 89.0 0.0 7.7e-25 87.6 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY91395.1 - 1.4e-17 63.5 2.3 1.1e-07 31.0 0.3 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ORY91395.1 - 0.0025 17.2 0.0 0.0064 15.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1241 PF06840.11 ORY91395.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DNA_pol3_gamma3 PF12169.8 ORY91395.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III AAA_11 PF13086.6 ORY91395.1 - 0.13 12.0 0.8 0.24 11.2 0.8 1.3 1 0 0 1 1 1 0 AAA domain DUF1308 PF07000.11 ORY91396.1 - 1.6e-29 103.0 0.0 3.8e-29 101.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 ORY91396.1 - 1.8e-09 37.2 0.1 0.0013 18.0 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5614) DUF4404 PF14357.6 ORY91396.1 - 0.021 15.5 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) CENP-B_dimeris PF09026.10 ORY91396.1 - 0.057 13.8 4.4 0.1 13.0 4.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cytochrom_C552 PF02335.15 ORY91397.1 - 0.071 12.0 1.4 0.078 11.9 1.4 1.0 1 0 0 1 1 1 0 Cytochrome c552 Cu-oxidase_2 PF07731.14 ORY91398.1 - 6e-43 145.9 5.8 1.3e-36 125.4 0.6 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 ORY91398.1 - 1.5e-34 119.4 1.9 1.5e-32 112.9 0.2 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY91398.1 - 1.9e-34 118.2 4.4 2.6e-33 114.5 0.1 3.5 4 0 0 4 4 4 1 Multicopper oxidase FA_hydroxylase PF04116.13 ORY91399.1 - 1.1e-24 87.3 20.3 1.1e-24 87.3 20.3 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MRP-S26 PF14943.6 ORY91400.1 - 5.2e-06 26.5 19.5 5.2e-06 26.5 19.5 2.0 2 1 0 2 2 2 1 Mitochondrial ribosome subunit S26 TFIIA PF03153.13 ORY91400.1 - 5.1 7.0 16.8 5.9 6.8 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 ORY91400.1 - 7.6 5.1 7.0 9 4.9 7.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HlyIII PF03006.20 ORY91401.1 - 8.3e-63 212.1 24.5 9.7e-63 211.9 24.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related TMEM95 PF15203.6 ORY91401.1 - 0.079 12.6 0.2 3 7.5 0.1 2.2 2 0 0 2 2 2 0 TMEM95 family SnAC PF14619.6 ORY91401.1 - 0.2 12.3 0.0 0.29 11.8 0.0 1.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Homeobox_KN PF05920.11 ORY91402.1 - 8.9e-19 67.1 2.1 2.1e-18 65.9 2.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY91402.1 - 1.7e-07 31.0 1.1 3.7e-07 29.9 1.1 1.6 1 0 0 1 1 1 1 Homeodomain FTA2 PF13095.6 ORY91402.1 - 0.099 12.2 0.4 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ndc1_Nup PF09531.10 ORY91402.1 - 0.4 9.3 9.9 0.51 9.0 9.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Homeobox_KN PF05920.11 ORY91405.1 - 5.5e-19 67.8 0.3 9.8e-19 67.0 0.3 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY91405.1 - 1.9e-06 27.6 0.1 3.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Homeodomain CBM_21 PF03370.13 ORY91406.1 - 3.4e-29 101.3 0.6 8.1e-29 100.1 0.6 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY91406.1 - 5.8e-10 39.6 2.0 1.5e-09 38.3 2.0 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Brix PF04427.18 ORY91407.1 - 4.4e-38 131.3 0.4 4.4e-38 131.3 0.4 1.4 2 0 0 2 2 2 1 Brix domain p450 PF00067.22 ORY91408.1 - 1.5e-72 244.8 0.1 1.7e-72 244.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2273 PF10031.9 ORY91409.1 - 0.24 11.4 4.2 1.7 8.7 2.2 2.0 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) ECH_1 PF00378.20 ORY91410.1 - 5.2e-51 173.4 0.0 6.8e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY91410.1 - 2.3e-30 106.2 0.1 5.3e-30 105.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UPF0444 PF15475.6 ORY91410.1 - 0.072 13.4 2.7 0.094 13.0 1.4 1.8 1 1 1 2 2 2 0 Transmembrane protein C12orf23, UPF0444 BET PF17035.5 ORY91411.1 - 1.6e-06 28.2 0.3 1.6e-06 28.2 0.3 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation CDC45 PF02724.14 ORY91411.1 - 0.072 11.4 17.5 0.05 11.9 1.4 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF2992 PF11208.8 ORY91411.1 - 2.9 8.1 6.6 1 9.6 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Ribosomal_L13e PF01294.18 ORY91412.1 - 2.4e-81 271.9 8.2 3.4e-81 271.4 8.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e WRKY PF03106.15 ORY91414.1 - 2.2e-11 43.8 2.6 4e-11 43.0 2.6 1.4 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.16 ORY91414.1 - 0.0056 16.8 0.5 0.0085 16.2 0.5 1.3 1 0 0 1 1 1 1 FLYWCH zinc finger domain Fungal_trans PF04082.18 ORY91415.1 - 1.5e-22 79.9 1.4 3.2e-22 78.8 1.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.28 ORY91416.1 - 1.1e-10 42.3 3.1 1.8e-10 41.7 3.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ETF PF01012.21 ORY91417.1 - 1.4e-43 148.9 10.1 2.1e-43 148.3 10.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 ORY91417.1 - 1.4e-35 121.1 0.6 1.4e-35 121.1 0.6 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Polyoma_coat2 PF00761.20 ORY91417.1 - 1.8 8.2 5.2 1.4 8.5 2.6 1.9 1 1 1 2 2 2 0 Polyomavirus coat protein KilA-N PF04383.13 ORY91419.1 - 0.0012 18.6 0.0 0.0042 16.9 0.0 1.9 1 1 1 2 2 2 1 KilA-N domain PPTA PF01239.22 ORY91419.1 - 0.087 12.6 0.3 0.17 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat zf-C2H2 PF00096.26 ORY91420.1 - 7.8e-17 60.7 25.6 1.2e-06 28.6 3.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY91420.1 - 1.1e-15 57.3 23.2 1.2e-08 35.0 1.0 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY91420.1 - 6.5e-10 39.0 23.2 0.00097 19.8 3.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY91420.1 - 7.5e-08 32.2 20.0 1.8e-05 24.6 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY91420.1 - 2.4e-05 24.5 12.6 0.069 13.5 0.9 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY91420.1 - 0.0013 19.1 15.3 0.28 11.6 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-MYST PF17772.1 ORY91420.1 - 0.0028 17.2 8.5 0.25 11.0 4.9 2.7 1 1 1 2 2 2 2 MYST family zinc finger domain BolA PF01722.18 ORY91420.1 - 0.0046 17.2 5.2 0.19 12.0 3.7 2.1 1 1 1 2 2 2 1 BolA-like protein zf-C2HC_2 PF13913.6 ORY91420.1 - 0.01 15.7 0.2 0.01 15.7 0.2 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type OSTMP1 PF09777.9 ORY91420.1 - 0.018 14.4 3.3 0.023 14.1 3.3 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Zn-ribbon_8 PF09723.10 ORY91420.1 - 0.028 14.5 9.4 0.75 10.0 3.0 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 ORY91420.1 - 0.039 14.6 8.0 1.4 9.6 0.1 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zinc-ribbons_6 PF07191.12 ORY91420.1 - 0.041 13.9 7.8 1.2 9.1 1.6 2.7 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_8 PF15909.5 ORY91420.1 - 0.041 14.2 9.8 0.15 12.4 9.3 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 ORY91420.1 - 0.042 14.3 17.3 0.15 12.5 2.0 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 ORY91420.1 - 0.12 12.7 13.3 0.06 13.6 7.1 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf_ZIC PF18366.1 ORY91420.1 - 0.33 11.1 7.7 7.1 6.8 0.1 3.1 1 1 2 3 3 3 0 Zic proteins zinc finger domain GAGA PF09237.11 ORY91420.1 - 0.73 9.7 8.5 0.072 12.9 3.8 1.8 1 1 1 2 2 2 0 GAGA factor zf-trcl PF13451.6 ORY91420.1 - 0.78 9.7 6.6 15 5.5 0.1 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 ORY91420.1 - 0.79 10.5 6.3 9.6 7.0 6.3 2.0 1 1 0 1 1 1 0 zinc-ribbon family zf_UBZ PF18439.1 ORY91420.1 - 0.81 9.3 10.8 1.6 8.4 1.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 ORY91420.1 - 2.2 8.0 17.0 2.1 8.1 0.1 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Arc_trans_TRASH PF08394.10 ORY91420.1 - 3 8.3 7.4 16 6.0 0.2 3.1 3 0 0 3 3 3 0 Archaeal TRASH domain zf-LYAR PF08790.11 ORY91420.1 - 3.5 7.6 13.0 1.1 9.2 0.9 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger PHD PF00628.29 ORY91420.1 - 4.3 7.3 11.0 3.9 7.4 4.3 2.6 1 1 1 2 2 2 0 PHD-finger OrfB_Zn_ribbon PF07282.11 ORY91420.1 - 7.1 6.6 10.3 2.6 8.0 4.2 2.4 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 ORY91420.1 - 7.3 6.4 9.3 4.7 7.0 0.2 3.0 3 0 0 3 3 3 0 Rubredoxin metal binding domain SRP54 PF00448.22 ORY91421.1 - 4.5e-78 261.4 0.2 8.5e-78 260.5 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ORY91421.1 - 8.9e-33 112.9 3.2 8.9e-33 112.9 3.2 4.2 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 ORY91421.1 - 9.3e-20 70.6 2.1 2.8e-19 69.1 2.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 ORY91421.1 - 1e-07 31.7 0.5 2.5e-06 27.2 0.3 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ORY91421.1 - 1.1e-05 24.8 0.0 2.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 ORY91421.1 - 4e-05 23.8 0.0 0.00012 22.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 ORY91421.1 - 6.9e-05 22.9 0.0 0.00025 21.1 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 ORY91421.1 - 0.00015 22.2 0.1 0.00069 20.0 0.1 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY91421.1 - 0.00031 21.1 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ORY91421.1 - 0.00034 20.4 0.2 0.0014 18.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY91421.1 - 0.00046 20.2 0.1 0.0015 18.6 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRPRB PF09439.10 ORY91421.1 - 0.0016 17.9 0.4 1.2 8.6 0.0 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MeaB PF03308.16 ORY91421.1 - 0.0046 16.0 0.1 0.019 14.0 0.0 2.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 ORY91421.1 - 0.0052 16.7 0.6 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 ORY91421.1 - 0.0074 16.2 0.1 0.028 14.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 ORY91421.1 - 0.0078 16.0 0.0 4.5 7.0 0.0 2.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 ORY91421.1 - 0.0086 15.8 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 ORY91421.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ORY91421.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 ORY91421.1 - 0.015 15.4 0.1 0.07 13.2 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORY91421.1 - 0.017 14.9 2.1 0.025 14.4 0.1 2.3 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 ORY91421.1 - 0.024 15.2 0.1 0.12 12.9 0.0 2.4 2 1 0 2 2 1 0 AAA domain MipZ PF09140.11 ORY91421.1 - 0.04 13.2 0.2 1.1 8.5 0.2 2.3 1 1 0 1 1 1 0 ATPase MipZ AAA_22 PF13401.6 ORY91421.1 - 0.055 13.7 0.6 0.23 11.7 0.2 2.4 2 1 0 2 2 1 0 AAA domain AAA PF00004.29 ORY91421.1 - 0.058 13.8 1.0 0.49 10.8 0.3 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ORY91421.1 - 0.061 13.2 0.5 0.26 11.2 0.5 2.2 1 1 0 1 1 1 0 NTPase AAA_19 PF13245.6 ORY91421.1 - 0.063 13.6 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain DNA_pol3_chi PF04364.13 ORY91421.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC Paramyxo_P PF01806.17 ORY91421.1 - 0.09 12.2 0.4 15 4.9 0.2 2.7 2 1 1 3 3 3 0 Paramyxovirinae P phosphoprotein C-terminal region SWC7 PF17330.2 ORY91421.1 - 0.092 12.8 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 VirC1 PF07015.11 ORY91421.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein HflK_N PF12221.8 ORY91421.1 - 0.12 12.4 4.3 0.95 9.5 0.5 2.8 1 1 1 2 2 2 0 Bacterial membrane protein N terminal DNA_ligase_A_N PF04675.14 ORY91421.1 - 0.19 12.1 1.0 1.3 9.3 0.1 2.6 2 1 1 3 3 3 0 DNA ligase N terminus DUF2201 PF09967.9 ORY91421.1 - 0.19 11.8 0.6 9.1 6.4 0.1 3.1 3 1 1 4 4 3 0 VWA-like domain (DUF2201) betaPIX_CC PF16523.5 ORY91421.1 - 1.5 8.7 6.2 0.19 11.6 0.5 2.3 3 0 0 3 3 2 0 betaPIX coiled coil Melittin PF01372.17 ORY91423.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Melittin OrfB_Zn_ribbon PF07282.11 ORY91424.1 - 0.012 15.5 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SR-25 PF10500.9 ORY91425.1 - 0.52 9.9 15.8 1 8.9 15.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 ORY91425.1 - 2.4 6.1 8.0 2.8 5.9 8.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ras PF00071.22 ORY91426.1 - 9.2e-43 145.6 0.0 1.1e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY91426.1 - 3.2e-26 91.9 0.0 4.9e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY91426.1 - 4.6e-09 36.0 0.0 6.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 ORY91426.1 - 0.00081 19.2 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 ORY91426.1 - 0.00094 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 ORY91426.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 ORY91426.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 ORY91426.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 ORY91426.1 - 0.035 13.5 0.0 0.084 12.3 0.0 1.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 ORY91426.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY91426.1 - 0.074 12.9 0.0 4.7 7.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 ORY91426.1 - 0.092 12.5 0.0 5.4 6.7 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_32 PF13654.6 ORY91426.1 - 0.11 11.2 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 ORY91426.1 - 0.12 11.2 0.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 ORY91426.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.16 ORY91427.1 - 2.8e-53 181.1 35.9 9.4e-53 179.4 35.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY91427.1 - 1.2e-11 44.2 33.2 3.3e-11 42.7 9.6 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 ORY91427.1 - 0.13 10.6 3.2 0.96 7.7 2.2 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EphA2_TM PF14575.6 ORY91427.1 - 0.31 12.0 3.0 6.9 7.6 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 ORY91427.1 - 1.2 9.0 5.1 2.5 8.0 0.3 2.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 MotA_ExbB PF01618.16 ORY91427.1 - 2.7 7.8 4.9 35 4.2 0.0 3.4 3 1 1 4 4 4 0 MotA/TolQ/ExbB proton channel family FeoB_C PF07664.12 ORY91427.1 - 6.9 6.4 7.3 25 4.6 1.0 3.4 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus DUF1741 PF08427.10 ORY91428.1 - 3e-55 187.4 0.3 5.3e-55 186.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Glyco_hydro_16 PF00722.21 ORY91429.1 - 3.1e-24 85.4 0.2 3.9e-24 85.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DNA_methylase PF00145.17 ORY91430.1 - 1.6e-41 142.8 0.0 1.8e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Band_7 PF01145.25 ORY91431.1 - 6.8e-24 84.8 2.7 1e-23 84.3 2.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PIG-X PF08320.12 ORY91432.1 - 2.2e-32 112.7 0.3 2.7e-32 112.4 0.3 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 HK_sensor PF16750.5 ORY91433.1 - 0.0042 17.4 1.3 0.0042 17.4 1.3 2.0 2 1 0 2 2 2 1 Sensor domain of 2-component histidine kinase NPR2 PF06218.11 ORY91433.1 - 0.025 13.4 1.4 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Nitrogen permease regulator 2 V-ATPase_G_2 PF16999.5 ORY91433.1 - 0.041 14.3 3.0 0.078 13.4 2.3 1.8 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ECH_2 PF16113.5 ORY91433.1 - 0.49 9.8 5.4 0.49 9.8 4.6 1.3 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Muted PF14942.6 ORY91433.1 - 1.7 9.0 12.9 0.99 9.7 9.2 2.2 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Casc1_N PF15927.5 ORY91433.1 - 2.3 7.9 7.3 1.8 8.2 4.6 2.0 1 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus CCDC53 PF10152.9 ORY91433.1 - 4.5 7.7 8.8 7.1 7.0 8.6 1.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex ResIII PF04851.15 ORY91434.1 - 1e-14 54.9 0.0 1.6e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY91434.1 - 1.7e-10 41.2 0.0 5.3e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY91434.1 - 0.00014 21.7 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY91434.1 - 0.0071 16.0 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DDE_Tnp_IS1595 PF12762.7 ORY91436.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 ISXO2-like transposase domain PhoLip_ATPase_C PF16212.5 ORY91437.1 - 1.5e-73 247.6 27.9 1.5e-73 247.6 27.9 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY91437.1 - 7.1e-23 80.1 2.2 1.1e-22 79.5 0.2 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY91437.1 - 9.5e-12 44.8 0.0 7.5e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY91437.1 - 9.2e-10 38.3 1.2 1e-07 31.6 0.0 3.1 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORY91437.1 - 1.2e-09 38.8 1.5 0.00056 20.3 0.8 3.8 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY91437.1 - 0.0013 18.6 0.2 0.0057 16.4 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UPF0542 PF15086.6 ORY91437.1 - 0.75 9.8 3.6 0.38 10.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Rpr2 PF04032.16 ORY91816.1 - 7.3e-18 64.6 1.4 1.2e-17 64.0 1.4 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TFIIS_C PF01096.18 ORY91816.1 - 0.14 12.0 2.2 0.28 11.1 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DZR PF12773.7 ORY91816.1 - 0.32 11.0 3.6 2 8.5 3.7 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RRN7 PF11781.8 ORY91816.1 - 6.1 6.6 5.7 3.7 7.3 0.3 2.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Mhr1 PF12829.7 ORY91817.1 - 5.8e-09 35.9 0.8 4.3e-08 33.1 0.8 2.2 1 1 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination SNF2_N PF00176.23 ORY91817.1 - 0.038 12.7 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain Rsm22 PF09243.10 ORY91817.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 UAA PF08449.11 ORY91818.1 - 1.3e-10 41.0 12.0 1.5e-10 40.8 12.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY91818.1 - 0.00025 21.2 6.1 0.00025 21.2 6.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 ORY91818.1 - 0.31 11.7 15.5 0.23 12.1 3.4 2.9 2 1 1 3 3 3 0 Small Multidrug Resistance protein SNO PF01174.19 ORY91819.1 - 9.1e-57 191.9 0.0 1e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORY91819.1 - 7.9e-09 35.4 0.0 1.2e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 ORY91819.1 - 3e-06 27.1 0.0 5.6e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 ORY91819.1 - 9.4e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 ORY91819.1 - 0.0045 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family XPG_I PF00867.18 ORY91823.1 - 1.7e-05 25.1 0.0 2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 XPG I-region Polysacc_deac_1 PF01522.21 ORY91824.1 - 1.7e-26 92.6 0.0 2.9e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase RNA_pol_Rpc4 PF05132.14 ORY91824.1 - 5.1 7.5 9.1 7.8 6.9 9.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Astro_capsid_p PF12226.8 ORY91824.1 - 6.8 5.7 10.7 8.9 5.3 10.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Tim54 PF11711.8 ORY91824.1 - 7.3 5.3 11.9 33 3.1 12.2 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Cmc1 PF08583.10 ORY91825.1 - 0.00034 20.6 3.1 0.00034 20.6 3.1 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like IER PF05760.12 ORY91825.1 - 0.76 10.0 10.6 0.92 9.8 10.6 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Hid1 PF12722.7 ORY91825.1 - 2.5 6.1 8.5 2.7 6.0 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 ORY91825.1 - 6.9 5.3 9.1 7.5 5.2 9.1 1.1 1 0 0 1 1 1 0 Presenilin Kinesin PF00225.23 ORY91826.1 - 2.3e-96 322.7 0.1 2.3e-96 322.7 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY91826.1 - 5.9e-17 62.0 0.1 2.5e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3605 PF12239.8 ORY91827.1 - 1.4e-26 93.6 1.6 4.3e-20 72.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3605) CBFD_NFYB_HMF PF00808.23 ORY91828.1 - 7.8e-17 61.3 1.3 1.2e-16 60.7 1.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY91828.1 - 6.6e-06 26.5 1.2 6.6e-06 26.5 1.2 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RIC1 PF07064.13 ORY91828.1 - 0.039 13.3 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 RIC1 Pkinase PF00069.25 ORY91829.1 - 5.1e-52 176.8 0.0 6.6e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91829.1 - 3.2e-37 128.2 0.0 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY91829.1 - 2.2e-05 23.4 0.0 3.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY91829.1 - 0.035 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORY91829.1 - 0.092 12.7 0.0 0.31 10.9 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 ORY91830.1 - 7.7e-09 35.6 0.4 2.2e-08 34.1 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY91830.1 - 1.6e-06 28.3 2.2 1.8e-06 28.1 0.3 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Med9 PF07544.13 ORY91830.1 - 0.00058 19.9 5.0 0.62 10.2 0.0 3.2 3 0 0 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 Stathmin PF00836.19 ORY91830.1 - 0.0031 17.5 2.9 0.0031 17.5 2.9 2.8 3 0 0 3 3 3 1 Stathmin family SLIDE PF09111.10 ORY91830.1 - 0.039 14.0 2.4 0.22 11.5 0.0 2.9 2 1 0 2 2 2 0 SLIDE DUF4140 PF13600.6 ORY91830.1 - 1.1 9.8 3.5 10 6.7 0.0 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3446 PF11928.8 ORY91832.1 - 8.4 6.8 11.8 11 6.3 11.8 1.3 1 1 0 1 1 1 0 Early growth response N-terminal domain Acetyltransf_1 PF00583.25 ORY91833.1 - 1.9e-17 63.6 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY91833.1 - 3.7e-14 52.8 0.1 4.6e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY91833.1 - 1.9e-11 44.2 0.1 2.6e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY91833.1 - 1.3e-07 31.9 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 ORY91833.1 - 7.7e-05 22.4 0.0 8.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 ORY91833.1 - 0.00077 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 ORY91833.1 - 0.0018 18.5 0.0 0.0031 17.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY91833.1 - 0.0032 17.6 0.0 0.0094 16.1 0.0 1.7 1 1 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 ORY91833.1 - 0.012 15.1 0.1 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 ORY91833.1 - 0.054 14.2 0.0 0.07 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 ORY91833.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Nudix hydrolase domain ABC_membrane PF00664.23 ORY91834.1 - 8.6e-05 22.3 0.1 8.6e-05 22.3 0.1 3.9 4 1 1 5 5 5 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY91834.1 - 0.0004 20.9 0.0 0.003 18.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter CN_hydrolase PF00795.22 ORY91835.1 - 2.1e-54 184.6 0.1 2.4e-54 184.4 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Nup35_RRM PF05172.13 ORY91836.1 - 1.8e-14 53.5 0.1 5.9e-14 51.9 0.1 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 ORY91836.1 - 9e-09 35.2 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 ORY91836.1 - 0.019 14.8 0.0 0.05 13.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANF_receptor PF01094.28 ORY91837.1 - 4e-32 111.7 0.7 5.1e-32 111.3 0.7 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY91837.1 - 2.7e-15 56.9 2.9 3.4e-15 56.6 2.9 1.2 1 0 0 1 1 1 1 Periplasmic binding protein YpsA PF06908.11 ORY91837.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 YspA SLOG family 7tm_3 PF00003.22 ORY91838.1 - 1.2e-34 120.1 27.0 1.6e-34 119.7 27.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2460 PF09343.10 ORY91838.1 - 0.042 13.4 0.3 0.072 12.6 0.3 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) LapA_dom PF06305.11 ORY91838.1 - 2.7 7.9 6.6 0.82 9.5 0.3 3.3 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Ribosomal_L28 PF00830.19 ORY91839.1 - 3.1e-22 78.5 0.3 4.4e-22 78.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family ADIP PF11559.8 ORY91841.1 - 0.01 15.9 15.2 0.01 15.9 15.2 3.9 3 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 ORY91841.1 - 0.011 15.3 10.5 0.011 15.3 10.5 3.2 2 1 0 3 3 3 0 Leucine zipper WD40_alt PF14077.6 ORY91841.1 - 0.012 15.4 6.2 0.66 9.9 0.1 3.7 4 0 0 4 4 4 0 Alternative WD40 repeat motif TRAF_BIRC3_bd PF16673.5 ORY91841.1 - 0.048 13.5 0.5 0.048 13.5 0.5 3.8 3 2 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Vac_Fusion PF02346.16 ORY91841.1 - 0.067 12.8 0.1 0.18 11.5 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 RBD-FIP PF09457.10 ORY91841.1 - 0.27 11.2 3.6 0.2 11.6 0.4 2.5 2 0 0 2 2 2 0 FIP domain QRPTase_C PF01729.19 ORY91842.1 - 1.4e-57 194.2 0.1 1.7e-57 193.9 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ORY91842.1 - 3.6e-19 68.6 0.0 8.2e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMP-TENI PF02581.17 ORY91842.1 - 0.04 13.2 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase NAD_binding_10 PF13460.6 ORY91842.1 - 0.047 13.6 0.1 0.079 12.9 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding IMPDH PF00478.25 ORY91842.1 - 0.048 12.6 0.1 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain XLF PF09302.11 ORY91843.1 - 1.6e-08 34.9 0.1 1.8e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component PAXX PF15384.6 ORY91843.1 - 0.067 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 AMP-binding PF00501.28 ORY91845.1 - 2.1e-97 326.4 0.0 2.7e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY91845.1 - 0.016 16.2 0.0 0.085 13.8 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY91846.1 - 4.3e-38 130.9 0.2 7e-38 130.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY91846.1 - 3.1e-23 81.8 0.1 5.7e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY91846.1 - 2.9e-20 72.2 0.0 6.5e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY91846.1 - 1.7e-15 57.6 0.0 6.7e-15 55.7 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY91846.1 - 0.0002 21.7 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Senescence PF06911.12 ORY91847.1 - 2.1e-15 57.5 0.3 4e-15 56.6 0.3 1.5 1 1 0 1 1 1 1 Senescence-associated protein DSPc PF00782.20 ORY91848.1 - 2.1e-33 115.0 0.0 3.3e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY91848.1 - 3.4e-05 23.5 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.14 ORY91848.1 - 0.054 13.7 2.5 0.057 13.6 0.1 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PTPlike_phytase PF14566.6 ORY91848.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Rsm1 PF08600.10 ORY91848.1 - 0.96 9.6 3.5 1.3 9.2 0.9 2.4 3 0 0 3 3 3 0 Rsm1-like DUF2786 PF10979.8 ORY91848.1 - 5.6 7.0 6.1 53 3.8 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) zinc_ribbon_4 PF13717.6 ORY91848.1 - 7.1 6.7 9.0 2 8.4 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon domain NOT2_3_5 PF04153.18 ORY91849.1 - 7.5e-28 97.2 0.3 7.5e-28 97.2 0.3 1.9 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family Spt20 PF12090.8 ORY91849.1 - 4.9 6.7 13.9 8.8 5.9 13.9 1.4 1 0 0 1 1 1 0 Spt20 family Vps5 PF09325.10 ORY91850.1 - 5.7e-22 78.4 5.5 6.3e-16 58.6 1.5 2.2 2 0 0 2 2 2 2 Vps5 C terminal like PX PF00787.24 ORY91850.1 - 9.4e-21 73.9 1.3 1.5e-20 73.3 0.3 1.8 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 ORY91850.1 - 9.6e-07 28.7 0.8 0.0062 16.3 0.0 2.3 2 0 0 2 2 2 2 BAR domain of APPL family CDT1_C PF16679.5 ORY91850.1 - 0.071 13.5 0.2 9.1 6.8 0.0 2.4 1 1 1 2 2 2 0 DNA replication factor Cdt1 C-terminal domain ATG22 PF11700.8 ORY91851.1 - 3.7e-107 358.9 23.6 4.4e-107 358.7 23.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY91851.1 - 3.1e-14 52.7 38.8 5.3e-07 28.9 13.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily AMP-binding PF00501.28 ORY91852.1 - 8.8e-95 317.8 0.0 1.1e-94 317.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY91852.1 - 7.6e-15 55.7 0.0 1.6e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VASt PF16016.5 ORY91855.1 - 3.9e-32 111.8 0.1 7.5e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 ORY91855.1 - 4.8e-23 82.1 3.8 4.8e-23 82.1 3.8 1.8 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 ORY91855.1 - 2.1e-12 47.5 0.1 6.1e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 PH domain CENP-T_C PF15511.6 ORY91855.1 - 0.043 13.9 0.2 0.83 9.8 0.0 2.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold PH_9 PF15410.6 ORY91855.1 - 0.11 12.9 0.2 0.78 10.1 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 ORY91855.1 - 0.11 12.9 1.0 4.7 7.7 1.0 3.0 1 1 0 1 1 1 0 Pleckstrin homology domain GRAM PF02893.20 ORY91855.1 - 0.13 12.2 0.0 0.41 10.6 0.0 1.9 1 0 0 1 1 1 0 GRAM domain DUF713 PF05218.14 ORY91855.1 - 0.61 9.8 4.4 4.2 7.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF713) IHABP4_N PF16174.5 ORY91855.1 - 6.3 7.4 8.0 19 5.8 8.0 1.8 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Ndufs5 PF10200.9 ORY91856.1 - 0.0003 21.0 0.8 0.0004 20.6 0.8 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa NDUF_B7 PF05676.13 ORY91856.1 - 0.0028 17.3 1.8 0.0048 16.6 1.8 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 ORY91856.1 - 0.005 17.0 1.0 0.005 17.0 1.0 2.1 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 ORY91856.1 - 0.037 14.0 3.3 0.053 13.5 3.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 ORY91856.1 - 0.044 14.1 1.4 0.069 13.5 1.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 ORY91856.1 - 1.6 9.1 5.3 2.7 8.4 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Y_phosphatase PF00102.27 ORY91858.1 - 0.00061 19.4 0.0 0.00077 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY91858.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF1324 PF07038.11 ORY91858.1 - 0.035 14.4 0.1 0.083 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) Zn_clus PF00172.18 ORY91860.1 - 0.014 15.5 14.6 0.025 14.7 14.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM199X PF15814.5 ORY91860.1 - 0.5 9.4 4.2 0.95 8.5 4.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X Ribosomal_L16 PF00252.18 ORY91861.1 - 1e-45 155.0 0.2 1.3e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HLH PF00010.26 ORY91862.1 - 7.3e-13 48.3 1.3 7.3e-13 48.3 1.3 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MRP-S33 PF08293.11 ORY91864.1 - 7.2e-32 109.5 0.1 8.2e-32 109.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 TBCC_N PF16752.5 ORY91865.1 - 0.033 14.6 0.8 1.2 9.6 0.4 2.8 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain GM_CSF PF01109.17 ORY91865.1 - 0.083 13.1 0.4 0.85 9.8 0.1 2.3 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Pol_alpha_B_N PF08418.10 ORY91865.1 - 0.11 12.5 3.2 1 9.3 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ribosomal_L14 PF00238.19 ORY91867.1 - 3.1e-36 124.1 0.2 3.7e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ras PF00071.22 ORY91868.1 - 8.5e-56 188.0 0.9 1.5e-29 102.6 0.2 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 ORY91868.1 - 3.3e-30 104.7 0.5 1e-23 83.8 0.1 2.5 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY91868.1 - 1.4e-08 34.4 0.2 1.5e-06 27.7 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY91868.1 - 0.00097 19.2 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY91868.1 - 0.002 18.1 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 ORY91868.1 - 0.0081 15.9 0.2 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.9 ORY91868.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Gtr1_RagA PF04670.12 ORY91868.1 - 0.089 12.1 0.1 0.25 10.7 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 ORY91868.1 - 0.17 12.4 0.1 0.47 11.0 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Anp1 PF03452.14 ORY91869.1 - 2e-85 286.4 0.0 2.4e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 ORY91869.1 - 3.7e-06 26.9 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 SWIRM PF04433.17 ORY91871.1 - 7.1e-07 29.5 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Ribosomal_L35Ae PF01247.18 ORY91873.1 - 5.4e-40 135.5 2.1 7.4e-40 135.0 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L35Ae ApbA PF02558.16 ORY91873.1 - 8.1e-30 103.5 0.0 1.2e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ORY91873.1 - 1.7e-26 92.8 0.0 3.2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal RimM PF01782.18 ORY91873.1 - 0.012 15.8 0.1 6.3 7.1 0.1 2.5 2 0 0 2 2 2 0 RimM N-terminal domain Kinesin PF00225.23 ORY91874.1 - 3e-93 312.4 0.0 4.2e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY91874.1 - 8.1e-15 55.0 0.0 3e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding SDA1 PF05285.12 ORY91874.1 - 0.19 11.1 13.9 0.39 10.1 10.5 2.2 2 0 0 2 2 2 0 SDA1 FAM176 PF14851.6 ORY91874.1 - 0.92 9.2 12.4 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.10 ORY91874.1 - 1.7 7.9 18.7 1.6 8.0 13.9 2.3 2 0 0 2 2 2 0 BUD22 E7 PF00527.18 ORY91874.1 - 5.1 7.4 6.1 15 5.9 0.0 3.0 2 0 0 2 2 2 0 E7 protein, Early protein Cep57_CLD_2 PF14197.6 ORY91876.1 - 0.0016 18.5 8.3 0.0016 18.5 8.3 3.6 2 1 2 4 4 4 1 Centrosome localisation domain of PPC89 ZapB PF06005.12 ORY91876.1 - 0.0072 16.8 12.8 0.0072 16.8 12.8 4.7 3 1 2 5 5 4 1 Cell division protein ZapB PKcGMP_CC PF16808.5 ORY91876.1 - 0.069 13.0 0.7 0.069 13.0 0.7 4.1 2 2 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 ORY91876.1 - 0.15 11.4 37.0 0.018 14.4 21.8 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ORY91876.1 - 0.19 10.6 41.8 0.016 14.1 15.7 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4172 PF13776.6 ORY91876.1 - 0.2 12.0 1.6 3.1 8.2 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) DUF1722 PF08349.11 ORY91876.1 - 0.21 11.9 9.5 0.16 12.3 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) DUF501 PF04417.12 ORY91876.1 - 0.73 9.6 11.8 0.13 12.1 5.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF501) Atg14 PF10186.9 ORY91876.1 - 1.3 8.1 37.0 0.03 13.4 26.8 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 ORY91876.1 - 1.4 8.2 29.4 2.7 7.2 8.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 ORY91876.1 - 2 8.5 35.2 3 7.9 12.3 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Tup_N PF08581.10 ORY91876.1 - 2.9 8.3 21.3 3 8.2 9.3 2.9 1 1 1 2 2 2 0 Tup N-terminal DUF641 PF04859.12 ORY91876.1 - 3.2 8.1 25.7 0.43 10.9 11.5 3.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 ORY91876.1 - 3.3 8.2 15.5 0.61 10.5 1.5 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 ORY91876.1 - 3.6 7.6 33.5 1.2 9.2 5.2 4.6 2 1 3 5 5 5 0 Prefoldin subunit Leu_zip PF15294.6 ORY91876.1 - 4 6.9 35.0 0.046 13.2 25.2 2.2 2 0 0 2 2 2 0 Leucine zipper ALIX_LYPXL_bnd PF13949.6 ORY91876.1 - 5.4 6.2 36.8 0.016 14.5 20.9 2.8 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DAHP_synth_1 PF00793.20 ORY91879.1 - 6.2e-101 336.9 0.0 7.2e-101 336.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PHP PF02811.19 ORY91880.1 - 1.8e-15 57.7 0.4 2.7e-15 57.1 0.4 1.3 1 0 0 1 1 1 1 PHP domain Glucosamine_iso PF01182.20 ORY91881.1 - 9.1e-20 71.5 0.0 1.4e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 6PF2K PF01591.18 ORY91882.1 - 3.5e-74 248.9 0.1 5.4e-74 248.2 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY91882.1 - 6.8e-30 104.2 0.0 2.6e-20 72.9 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY91882.1 - 1.5e-05 25.2 0.0 3.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORY91882.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF5128 PF17170.4 ORY91882.1 - 0.0069 15.6 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 6-bladed beta-propeller Zeta_toxin PF06414.12 ORY91882.1 - 0.0083 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sugar_tr PF00083.24 ORY91883.1 - 3.3e-105 352.6 18.2 4e-105 352.3 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY91883.1 - 3.3e-30 105.2 34.0 1.9e-21 76.4 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY91883.1 - 0.00034 19.2 0.9 0.00034 19.2 0.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Anophelin PF10731.9 ORY91883.1 - 0.018 14.9 0.1 0.054 13.4 0.1 1.8 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF697 PF05128.12 ORY91883.1 - 0.022 14.5 0.4 0.043 13.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF697) OATP PF03137.20 ORY91883.1 - 0.91 7.7 5.9 2.2 6.5 0.8 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PRA1 PF03208.19 ORY91885.1 - 3.4e-27 94.8 0.1 4.3e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 ORY91885.1 - 0.058 12.2 1.5 0.076 11.8 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tombus_P33 PF08500.10 ORY91885.1 - 0.28 11.1 0.0 0.39 10.7 0.0 1.1 1 0 0 1 1 1 0 Tombusvirus p33 Arginase PF00491.21 ORY91886.1 - 7e-92 307.9 0.1 8.8e-92 307.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family Vac7 PF12751.7 ORY91887.1 - 1.1e-19 71.2 15.9 4.1e-18 66.0 15.9 2.4 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 DEAD PF00270.29 ORY91890.1 - 1.3e-44 152.0 0.3 2.2e-44 151.3 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY91890.1 - 5.9e-31 107.1 0.1 6e-30 103.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY91890.1 - 1.2e-05 25.4 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY91890.1 - 0.0017 18.7 0.2 0.0039 17.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY91890.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 ORY91890.1 - 0.024 14.0 0.1 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CBFD_NFYB_HMF PF00808.23 ORY91891.1 - 1.3e-20 73.4 0.5 2.4e-20 72.6 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY91891.1 - 2.3e-16 60.3 0.1 2.3e-16 60.3 0.1 2.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 ORY91891.1 - 0.064 13.6 0.2 0.15 12.4 0.2 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X CoaE PF01121.20 ORY91891.1 - 0.62 9.7 0.0 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase DUF4366 PF14283.6 ORY91891.1 - 1.7 8.7 4.3 4.4 7.3 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Lin-8 PF03353.15 ORY91891.1 - 3.9 6.9 20.9 1.8 8.0 8.7 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SH3_9 PF14604.6 ORY91892.1 - 6.3e-09 35.6 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY91892.1 - 3.3e-05 23.4 0.0 6.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CYYR1 PF10873.8 ORY91892.1 - 0.0025 18.3 0.4 0.0025 18.3 0.4 3.2 3 0 0 3 3 3 1 Cysteine and tyrosine-rich protein 1 SH3_2 PF07653.17 ORY91892.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain CD99L2 PF12301.8 ORY91892.1 - 0.09 13.1 4.3 0.65 10.3 0.0 2.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 SUIM_assoc PF16619.5 ORY91892.1 - 0.85 9.7 13.0 0.11 12.6 5.4 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 ORY91892.1 - 2.8 6.4 8.1 4.3 5.8 8.1 1.3 1 0 0 1 1 1 0 Macoilin family Methyltransf_23 PF13489.6 ORY91893.1 - 2.1e-19 69.9 0.0 3.2e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY91893.1 - 7.9e-10 39.4 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY91893.1 - 4.6e-08 33.7 0.0 7.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY91893.1 - 1.5e-06 28.8 0.0 2.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY91893.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY91893.1 - 0.0027 17.1 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DRMBL PF07522.14 ORY91896.1 - 2.4e-07 30.9 0.0 6.1e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 ORY91896.1 - 7.8e-06 25.7 0.1 3.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORY91896.1 - 7.9e-05 22.3 0.9 0.0002 21.0 0.4 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY91896.1 - 0.009 16.0 5.2 0.017 15.1 3.4 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily SANT_DAMP1_like PF16282.5 ORY91896.1 - 0.24 11.6 2.7 0.76 10.0 2.7 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 APG17 PF04108.12 ORY91897.1 - 1.2e-69 235.3 18.8 1.4e-69 235.1 18.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 USP7_C2 PF14533.6 ORY91897.1 - 0.015 15.0 0.8 0.031 14.0 0.8 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal FTO_CTD PF12934.7 ORY91897.1 - 0.3 10.8 5.1 1.5 8.5 2.0 2.5 2 0 0 2 2 2 0 FTO C-terminal domain Holin_BhlA PF10960.8 ORY91897.1 - 0.36 10.8 15.2 8 6.5 0.3 4.2 4 0 0 4 4 4 0 BhlA holin family Mod_r PF07200.13 ORY91897.1 - 0.42 10.7 11.5 0.18 11.9 0.4 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Mce4_CUP1 PF11887.8 ORY91897.1 - 0.46 9.9 5.3 30 4.0 1.5 3.3 3 1 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF4164 PF13747.6 ORY91897.1 - 0.49 10.7 5.4 0.15 12.4 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF16 PF01519.16 ORY91897.1 - 0.82 10.2 8.8 8.8 6.9 0.2 3.5 2 1 2 4 4 4 0 Protein of unknown function DUF16 TACC_C PF05010.14 ORY91897.1 - 3 7.6 11.5 2.1 8.1 5.7 2.7 1 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-H PF05837.12 ORY91897.1 - 7.7 7.0 11.0 3.1 8.2 1.8 3.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DAGK_cat PF00781.24 ORY91898.1 - 6.8e-29 100.0 0.0 1.5e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain S36_mt PF10937.8 ORY91899.1 - 1.3e-15 59.0 1.5 2e-09 39.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial SVA PF05326.11 ORY91900.1 - 0.59 10.1 2.7 17 5.4 0.3 2.3 2 0 0 2 2 2 0 Seminal vesicle autoantigen (SVA) 5-FTHF_cyc-lig PF01812.20 ORY91901.1 - 3.7e-42 144.3 0.0 4.2e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family F-box-like PF12937.7 ORY91903.1 - 7.7e-15 54.5 0.7 1.5e-14 53.6 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY91903.1 - 1.1e-08 34.8 0.2 2.3e-08 33.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain Methyltransf_25 PF13649.6 ORY91904.1 - 1.7e-06 28.7 0.0 2.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY91904.1 - 3.3e-06 27.0 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY91904.1 - 0.00045 20.1 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 ORY91904.1 - 0.00051 19.6 0.0 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 ORY91904.1 - 0.0011 19.6 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY91904.1 - 0.0023 17.4 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ORY91904.1 - 0.0052 16.6 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 ORY91904.1 - 0.011 16.5 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 ORY91904.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 ORY91904.1 - 0.029 13.7 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 ORY91904.1 - 0.063 12.3 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 ORY91904.1 - 0.064 13.3 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Nuc_sug_transp PF04142.15 ORY91905.1 - 1.5e-113 379.2 7.7 1.7e-113 379.0 7.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 ORY91905.1 - 2.9e-09 37.2 27.3 1.2e-05 25.5 4.4 2.3 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 ORY91905.1 - 0.0021 17.7 7.1 0.0034 17.0 0.2 2.4 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 ORY91905.1 - 0.098 11.9 18.1 0.89 8.7 18.3 2.5 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport UAA PF08449.11 ORY91905.1 - 0.14 11.3 20.2 0.019 14.2 4.0 2.6 2 1 0 2 2 2 0 UAA transporter family TPT PF03151.16 ORY91905.1 - 0.14 11.4 9.3 0.021 14.2 3.2 2.5 2 2 0 2 2 2 0 Triose-phosphate Transporter family Chitin_synth_1 PF01644.17 ORY91906.1 - 1.5e-78 262.4 0.0 2.4e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY91906.1 - 2.9e-30 104.0 0.2 6.5e-30 102.9 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY91906.1 - 1.1e-22 80.4 0.5 4.4e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY91906.1 - 0.00049 20.1 15.2 0.02 14.8 15.2 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 PALP PF00291.25 ORY91907.1 - 2.5e-72 243.8 0.3 3.1e-72 243.5 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FUSC_2 PF13515.6 ORY91908.1 - 1e-13 51.5 18.4 2.3e-13 50.4 18.4 1.7 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY91908.1 - 6.7e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 ORY91908.1 - 0.00012 21.1 11.9 0.00025 20.0 11.9 1.5 1 0 0 1 1 1 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 ORY91908.1 - 0.00015 21.0 0.8 0.024 13.7 0.0 2.8 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal DUF3959 PF13105.6 ORY91908.1 - 0.32 10.5 2.3 0.54 9.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) FUSC PF04632.12 ORY91908.1 - 0.37 9.3 22.0 0.45 9.0 15.2 2.9 3 1 0 3 3 3 0 Fusaric acid resistance protein family Semialdhyde_dhC PF02774.18 ORY91910.1 - 0.026 14.6 0.0 0.03 14.4 0.0 1.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain HMG_box PF00505.19 ORY91911.1 - 5.9e-26 90.7 1.0 8.1e-26 90.2 1.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY91911.1 - 1.1e-15 58.0 1.3 1.6e-15 57.4 1.3 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 ORY91911.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain HMG_box_5 PF14887.6 ORY91911.1 - 0.041 13.8 0.2 0.081 12.9 0.2 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Zip PF02535.22 ORY91912.1 - 3.1e-52 177.8 14.1 3.1e-52 177.8 14.1 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter Cation_ATPase_C PF00689.21 ORY91912.1 - 0.086 12.5 12.4 0.049 13.3 6.6 2.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus GRIP PF01465.20 ORY91913.1 - 4.5e-14 52.1 0.6 2.2e-13 49.9 0.6 2.3 1 0 0 1 1 1 1 GRIP domain Uso1_p115_C PF04871.13 ORY91913.1 - 0.34 11.3 33.9 0.44 10.9 12.1 3.2 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GIT_CC PF16559.5 ORY91913.1 - 1.8 8.5 11.1 9.4 6.2 0.6 4.1 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3837 PF12939.7 ORY91913.1 - 6.1 7.3 9.2 7.8 7.0 0.0 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3837) YabA PF06156.13 ORY91913.1 - 7.1 7.3 25.5 0.43 11.2 3.1 3.5 2 1 1 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 ORY91913.1 - 8.1 6.6 18.7 0.42 10.7 5.1 3.8 3 1 0 3 3 3 0 bZIP transcription factor Spc29 PF17082.5 ORY91913.1 - 9.3 6.0 16.1 0.26 11.1 4.4 2.7 2 1 1 3 3 3 0 Spindle Pole Component 29 RPAP2_Rtr1 PF04181.13 ORY91914.1 - 4.1e-22 78.3 0.6 1.1e-21 76.9 0.6 1.8 1 0 0 1 1 1 1 Rtr1/RPAP2 family SR-25 PF10500.9 ORY91914.1 - 0.0059 16.2 7.0 0.012 15.2 7.0 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MatP_C PF17414.2 ORY91914.1 - 0.031 14.5 0.2 0.1 12.8 0.2 1.9 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain DUF3275 PF11679.8 ORY91914.1 - 3.1 7.7 9.7 0.97 9.4 6.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) zf-RING_2 PF13639.6 ORY91915.1 - 6e-06 26.5 5.3 1.6e-05 25.1 5.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY91915.1 - 0.0038 17.1 1.3 0.011 15.6 1.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DAG1 PF05454.11 ORY91915.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) zf-RING_5 PF14634.6 ORY91915.1 - 0.046 13.7 6.3 0.12 12.4 6.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain PA PF02225.22 ORY91915.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 PA domain zf-C3HC4_2 PF13923.6 ORY91915.1 - 0.65 9.9 10.0 8.4 6.3 10.0 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) JAB PF01398.21 ORY91919.1 - 8.4e-35 119.3 2.6 1.3e-34 118.7 0.9 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 ORY91919.1 - 1.9e-23 83.2 0.5 4.5e-23 82.0 0.5 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 ORY91919.1 - 0.0043 16.8 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 ORY91919.1 - 0.022 14.8 0.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Exo_endo_phos PF03372.23 ORY91920.1 - 3.3e-18 66.0 0.1 6.9e-18 65.0 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 ORY91920.1 - 2.9e-10 40.1 5.9 7.5e-10 38.8 5.9 1.7 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 ORY91920.1 - 6.5e-05 22.8 0.0 0.0039 17.0 0.0 2.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase STI1 PF17830.1 ORY91920.1 - 0.023 14.6 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 STI1 domain AvrPphF-ORF-2 PF09143.10 ORY91920.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 AvrPphF-ORF-2 AFP_2 PF18815.1 ORY91920.1 - 0.09 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial antifreeze protein repeat CYSTM PF12734.7 ORY91921.1 - 1e-11 44.9 7.5 1e-11 44.9 7.5 2.7 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance FOLN PF09289.10 ORY91922.1 - 0.19 11.9 2.8 0.47 10.7 0.8 2.1 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain CAP59_mtransfer PF11735.8 ORY91923.1 - 1.1e-65 221.7 0.0 1.4e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HTH_19 PF12844.7 ORY91923.1 - 0.0023 17.9 0.0 0.0082 16.1 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Glyco_tranf_2_4 PF13704.6 ORY91923.1 - 0.02 15.4 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DIOX_N PF14226.6 ORY91925.1 - 1.2e-35 122.8 0.1 2.3e-35 121.9 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY91925.1 - 1.8e-21 76.5 0.0 3.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CNH PF00780.22 ORY91926.1 - 2e-50 172.0 0.0 3.1e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY91926.1 - 1.5e-37 129.6 0.1 2.6e-37 128.8 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY91926.1 - 1.5e-19 70.4 0.0 6.5e-19 68.4 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORY91926.1 - 1.8e-10 40.7 0.0 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1917 PF08939.10 ORY91926.1 - 0.49 10.2 3.8 0.12 12.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) RabGAP-TBC PF00566.18 ORY91927.1 - 6.7e-49 166.4 0.3 6.7e-49 166.4 0.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 ORY91927.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 ORY91927.1 - 6.6e-06 25.6 0.5 0.016 15.1 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORY91927.1 - 7.2e-06 26.4 2.8 0.0057 17.1 0.3 3.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY91927.1 - 0.00052 19.4 0.3 0.064 12.8 0.2 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 ORY91927.1 - 0.0096 15.8 0.2 0.038 13.8 0.2 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY91927.1 - 0.076 12.5 0.3 0.41 10.2 0.2 2.3 2 0 0 2 2 2 0 EF hand NUP50 PF08911.11 ORY91927.1 - 0.29 11.8 3.9 0.97 10.1 3.9 1.9 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Cwf_Cwc_15 PF04889.12 ORY91927.1 - 1.5 8.5 20.2 2.6 7.7 20.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 ORY91927.1 - 4.1 6.9 16.2 6.9 6.2 16.2 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4909 PF16253.5 ORY91928.1 - 0.072 12.9 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) Ribosomal_L19e PF01280.20 ORY91929.1 - 6.5e-63 211.1 10.5 6.5e-63 211.1 10.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Peptidase_M3 PF01432.20 ORY91930.1 - 8.5e-148 493.4 1.0 1.4e-147 492.7 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 F_bP_aldolase PF01116.20 ORY91932.1 - 1.4e-73 247.8 0.0 1.6e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II HLH PF00010.26 ORY91933.1 - 8.9e-15 54.4 0.4 3.3e-14 52.6 0.4 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IPP-2 PF04979.14 ORY91933.1 - 0.026 15.3 4.2 0.074 13.8 4.3 1.8 1 1 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DUF5094 PF17015.5 ORY91933.1 - 3.1 7.9 4.7 6.6 6.8 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Glyco_transf_49 PF13896.6 ORY91934.1 - 1.8e-64 218.2 2.4 8.1e-52 176.6 0.4 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan KaiA PF07688.12 ORY91934.1 - 0.015 15.5 0.1 0.015 15.5 0.1 1.6 2 0 0 2 2 2 0 KaiA C-terminal domain Glyco_tranf_2_4 PF13704.6 ORY91934.1 - 0.11 13.0 1.4 0.37 11.4 1.4 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 F-box-like PF12937.7 ORY91935.1 - 3.1e-05 23.8 0.1 6.9e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY91935.1 - 0.011 15.6 1.3 0.026 14.4 0.0 2.4 2 1 0 2 2 2 0 F-box domain TPR_11 PF13414.6 ORY91935.1 - 0.02 14.6 2.6 1.3 8.7 0.1 3.2 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.17 ORY91935.1 - 0.02 15.0 0.1 0.056 13.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_8 PF13855.6 ORY91935.1 - 0.047 13.5 0.6 0.047 13.5 0.6 3.4 3 0 0 3 3 3 0 Leucine rich repeat TPR_12 PF13424.6 ORY91935.1 - 0.066 13.5 0.3 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 ORY91935.1 - 0.12 12.8 9.7 2.1 8.9 0.0 4.7 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) TPR_14 PF13428.6 ORY91935.1 - 0.52 11.3 2.4 1.6 9.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MTP18 PF10558.9 ORY91936.1 - 6.3e-62 208.5 10.1 4.4e-31 108.1 3.7 2.2 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) F-box-like PF12937.7 ORY91937.1 - 0.0014 18.4 2.5 0.002 18.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like Redoxin PF08534.10 ORY91937.1 - 0.014 15.1 0.1 0.073 12.8 0.1 2.0 1 1 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 ORY91937.1 - 0.02 14.8 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family DUF4898 PF16239.5 ORY91937.1 - 0.033 14.1 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) Lung_7-TM_R PF06814.13 ORY91938.1 - 1.4e-65 221.5 16.6 1.9e-65 221.1 16.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor RDD PF06271.12 ORY91938.1 - 0.14 12.4 0.2 0.14 12.4 0.2 3.6 2 1 0 2 2 2 0 RDD family BatA PF07584.11 ORY91938.1 - 4.9 7.6 9.1 2.9 8.3 4.2 2.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal La PF05383.17 ORY91939.1 - 8.9e-21 73.7 0.2 2.5e-20 72.2 0.2 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 ORY91939.1 - 3.1e-07 30.1 2.9 3.2e-07 30.0 0.6 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 ORY91939.1 - 0.00035 20.4 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) TAFII55_N PF04658.13 ORY91940.1 - 1.1e-52 178.0 3.0 1.1e-52 178.0 3.0 2.4 2 0 0 2 2 2 1 TAFII55 protein conserved region SURF2 PF05477.11 ORY91940.1 - 0.0092 15.7 17.9 0.019 14.7 16.7 2.0 2 0 0 2 2 2 1 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 ORY91940.1 - 0.024 13.0 17.8 0.029 12.7 17.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORY91940.1 - 1.3 7.2 31.7 2.3 6.3 31.7 1.4 1 0 0 1 1 1 0 Nop14-like family CENP-K PF11802.8 ORY91941.1 - 1.2e-26 93.9 7.0 1.8e-26 93.3 7.0 1.1 1 0 0 1 1 1 1 Centromere-associated protein K DUF3053 PF11254.8 ORY91941.1 - 0.28 10.7 8.6 0.51 9.9 8.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) MutS_III PF05192.18 ORY91941.1 - 0.69 10.1 6.2 1.1 9.5 6.2 1.3 1 0 0 1 1 1 0 MutS domain III Cdh1_DBD_1 PF18196.1 ORY91941.1 - 4.8 7.5 9.9 12 6.3 1.5 2.6 1 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 MFS_1 PF07690.16 ORY91942.1 - 6.7e-40 137.1 22.8 8.2e-40 136.8 22.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3682 PF12446.8 ORY91943.1 - 0.11 13.0 5.2 0.2 12.1 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CAF1A PF12253.8 ORY91943.1 - 0.74 10.0 4.7 2.1 8.6 0.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF4407 PF14362.6 ORY91945.1 - 0.13 11.5 16.6 0.016 14.6 9.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Mgr1 PF08602.10 ORY91945.1 - 0.42 9.4 9.9 0.81 8.4 9.7 1.6 1 1 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF489 PF04356.12 ORY91945.1 - 0.6 10.1 11.2 0.38 10.7 5.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF489) GAS PF13851.6 ORY91945.1 - 1.1 8.6 32.6 0.3 10.4 12.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ALMT PF11744.8 ORY91945.1 - 1.3 7.8 10.9 1.7 7.4 10.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DHR10 PF18595.1 ORY91945.1 - 1.4 9.0 32.7 1.2 9.3 8.4 3.2 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Lebercilin PF15619.6 ORY91945.1 - 1.4 8.6 33.4 0.31 10.7 22.5 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Dna2 PF08696.11 ORY91945.1 - 1.4 8.7 10.1 0.4 10.5 6.5 1.8 1 1 1 2 2 2 0 DNA replication factor Dna2 Fib_alpha PF08702.10 ORY91945.1 - 1.9 8.7 18.4 0.21 11.8 12.3 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 ORY91945.1 - 2.9 8.2 20.6 0.68 10.2 1.5 3.7 2 2 2 4 4 4 0 Uncharacterized conserved protein Fez1 PF06818.15 ORY91945.1 - 3 8.3 27.2 6.4 7.2 9.0 2.2 1 1 1 2 2 2 0 Fez1 Tweety PF04906.13 ORY91945.1 - 5.1 5.7 12.6 3 6.4 2.5 2.2 1 1 1 2 2 2 0 Tweety DUF641 PF04859.12 ORY91945.1 - 9.7 6.5 25.1 0.11 12.8 3.1 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) F-box-like PF12937.7 ORY91946.1 - 0.0084 16.0 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY91946.1 - 0.012 15.5 0.1 0.06 13.2 0.1 2.1 2 0 0 2 2 2 0 F-box domain CHD5 PF04420.14 ORY91947.1 - 3.9e-48 163.3 1.1 4.7e-48 163.1 1.1 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF3810 PF12725.7 ORY91947.1 - 0.02 14.3 0.6 0.025 14.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) T3SS_needle_E PF08988.10 ORY91947.1 - 0.054 13.6 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle SpuA_C PF18033.1 ORY91947.1 - 0.085 12.9 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 SpuA C-terminal Lectin_N PF03954.14 ORY91947.1 - 0.25 11.1 4.5 0.77 9.5 4.5 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain NAD_binding_10 PF13460.6 ORY91948.1 - 1.1e-07 31.9 0.1 2.2e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY91948.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NIF3 PF01784.18 ORY91949.1 - 7.4e-66 222.3 0.0 9.1e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Ribosomal_S8 PF00410.19 ORY91950.1 - 1.2e-19 70.5 0.0 7.2e-19 68.0 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 LSM PF01423.22 ORY91951.1 - 1.1e-18 66.7 0.2 1.3e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain Dus PF01207.17 ORY91952.1 - 1.7e-60 204.7 0.3 3.8e-60 203.6 0.3 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 ORY91952.1 - 0.0021 17.2 0.1 0.033 13.2 0.0 2.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ATG19_autophagy PF12744.7 ORY91952.1 - 0.038 13.2 0.2 0.093 11.9 0.0 1.6 2 0 0 2 2 2 0 Autophagy protein Atg19, Atg8-binding Glyco_transf_15 PF01793.16 ORY91953.1 - 1.7e-22 80.2 2.2 2.2e-22 79.8 2.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Med16 PF11635.8 ORY91954.1 - 1.1e-12 46.8 7.5 0.0005 18.1 3.0 3.1 2 1 1 3 3 3 3 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 ORY91954.1 - 0.00055 20.2 0.0 0.12 12.6 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY91954.1 - 0.0086 16.9 1.6 40 5.3 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat BRCT_2 PF16589.5 ORY91955.1 - 1.2e-05 25.7 0.0 3.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY91955.1 - 2.3e-05 24.7 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ORY91955.1 - 0.0034 17.6 0.0 0.046 14.0 0.0 2.3 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 ORY91955.1 - 0.023 14.6 0.2 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain BRCT_3 PF18428.1 ORY91955.1 - 0.17 12.0 0.0 0.86 9.7 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain GET2 PF08690.10 ORY91955.1 - 0.27 10.9 8.7 12 5.4 0.0 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 FAM60A PF15396.6 ORY91955.1 - 0.48 10.4 8.7 4.5 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein Family FAM60A 14-3-3 PF00244.20 ORY91955.1 - 0.64 9.5 0.0 0.64 9.5 0.0 2.1 2 0 0 2 2 2 0 14-3-3 protein DUF935 PF06074.12 ORY91955.1 - 0.75 8.5 8.7 0.3 9.8 5.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF935) DUF4192 PF13830.6 ORY91955.1 - 1.3 9.1 7.9 3.8 7.5 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DUF2852 PF11014.8 ORY91955.1 - 1.5 9.0 6.2 2.8 8.1 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) CDT1_C PF16679.5 ORY91955.1 - 3.9 8.0 9.9 0.89 10.0 5.9 2.0 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain CPSF100_C PF13299.6 ORY91955.1 - 6.5 6.9 10.1 35 4.5 0.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PHD PF00628.29 ORY91956.1 - 8.5e-17 60.8 20.3 4.5e-09 36.1 10.1 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 ORY91956.1 - 0.022 15.0 8.9 0.14 12.5 3.4 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHF12_MRG_bd PF16737.5 ORY91956.1 - 0.12 12.1 0.3 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain C1_1 PF00130.22 ORY91956.1 - 0.39 10.7 16.8 0.56 10.1 1.6 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 ORY91956.1 - 2.4 8.3 11.1 0.23 11.6 1.1 3.1 2 2 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-HC5HC2H_2 PF13832.6 ORY91956.1 - 3.4 7.9 7.7 1.3 9.2 2.2 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 ORY91956.1 - 7.4 6.3 12.6 10 5.8 1.4 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PITH PF06201.13 ORY91957.1 - 1.9e-39 135.3 3.5 2.7e-39 134.8 3.5 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 ORY91957.1 - 3.7e-29 100.7 0.1 8.4e-29 99.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY91957.1 - 2.2e-06 28.1 0.0 5.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY91957.1 - 3.6e-05 24.0 0.1 0.00035 20.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 ORY91957.1 - 0.00064 19.4 0.1 0.0014 18.3 0.0 1.6 2 0 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 ORY91957.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORY91957.1 - 0.0027 17.1 0.4 0.0051 16.2 0.1 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ORY91957.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 AhpC/TSA family DUF2847 PF11009.8 ORY91957.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF3557 PF12078.8 ORY91957.1 - 0.048 13.6 0.5 0.14 12.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) Scs3p PF10261.9 ORY91958.1 - 1.2e-52 178.9 23.2 2e-43 148.7 6.8 2.1 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Cytochrom_B_C PF00032.17 ORY91958.1 - 0.027 14.8 2.4 0.027 14.8 2.4 2.1 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Glyco_hydro_46 PF01374.18 ORY91959.1 - 5.7e-36 124.1 0.0 7.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 P22_portal PF16510.5 ORY91959.1 - 0.19 10.3 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein UQ_con PF00179.26 ORY91961.1 - 1.1e-37 128.8 0.0 1.6e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sporozoite_P67 PF05642.11 ORY91961.1 - 0.12 10.4 8.9 0.14 10.2 8.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 ORY91961.1 - 0.32 11.0 29.0 0.5 10.3 29.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 ORY91961.1 - 0.77 7.7 11.2 0.95 7.4 11.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MGC-24 PF05283.11 ORY91961.1 - 3.6 8.0 16.5 6 7.3 16.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NST1 PF13945.6 ORY91961.1 - 8.9 6.4 8.2 13 5.8 8.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-AN1 PF01428.16 ORY91962.1 - 9e-19 67.4 31.3 3e-12 46.5 4.6 3.6 3 1 1 4 4 4 2 AN1-like Zinc finger zinc_ribbon_10 PF10058.9 ORY91962.1 - 0.16 11.7 4.7 6.2 6.6 0.2 2.7 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Transp_Tc5_C PF04236.15 ORY91962.1 - 1 9.8 17.0 0.59 10.5 4.0 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain FYDLN_acid PF09538.10 ORY91962.1 - 2 9.2 9.1 13 6.5 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) IBR PF01485.21 ORY91962.1 - 5.1 7.4 25.9 0.33 11.2 7.8 3.0 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain DUF726 PF05277.12 ORY91963.1 - 4.1e-121 404.1 0.3 5.8e-121 403.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cwf_Cwc_15 PF04889.12 ORY91963.1 - 0.0027 17.5 13.7 0.0027 17.5 13.7 3.6 4 0 0 4 4 4 1 Cwf15/Cwc15 cell cycle control protein Tropomyosin_1 PF12718.7 ORY91964.1 - 6.8e-16 58.7 27.3 5.7e-15 55.7 27.3 1.9 1 1 0 1 1 1 1 Tropomyosin like Cg6151-P PF10233.9 ORY91964.1 - 2.2e-13 50.5 16.5 1.2e-08 35.2 7.6 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein CG6151-P Tropomyosin PF00261.20 ORY91964.1 - 3.8e-09 36.3 27.8 8.6e-08 31.8 27.8 2.0 1 1 0 1 1 1 1 Tropomyosin ATG16 PF08614.11 ORY91964.1 - 0.00032 21.0 21.6 0.00046 20.5 21.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 ORY91964.1 - 0.0012 18.4 19.9 0.0016 18.0 19.9 1.1 1 0 0 1 1 1 1 Leucine zipper Fez1 PF06818.15 ORY91964.1 - 0.0025 18.3 20.6 0.0035 17.8 20.6 1.1 1 0 0 1 1 1 1 Fez1 NPV_P10 PF05531.12 ORY91964.1 - 0.0033 17.8 6.6 0.61 10.6 0.5 2.7 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein GAS PF13851.6 ORY91964.1 - 0.0035 16.7 23.1 0.0053 16.1 23.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HOOK PF05622.12 ORY91964.1 - 0.0041 15.4 20.3 0.0053 15.0 20.3 1.0 1 0 0 1 1 1 1 HOOK protein IFT57 PF10498.9 ORY91964.1 - 0.0075 15.3 15.9 0.01 14.9 15.9 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 SpoIIIAH PF12685.7 ORY91964.1 - 0.0076 16.1 7.9 0.0093 15.8 7.9 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DHR10 PF18595.1 ORY91964.1 - 0.0093 16.0 16.0 0.0093 16.0 16.0 2.1 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain DUF5320 PF17253.2 ORY91964.1 - 0.012 16.7 0.2 0.012 16.7 0.2 2.6 2 1 0 2 2 1 0 Family of unknown function (DUF5320) CENP-F_leu_zip PF10473.9 ORY91964.1 - 0.02 14.9 29.6 0.17 11.9 15.7 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 ORY91964.1 - 0.025 13.5 27.0 0.11 11.3 27.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4201 PF13870.6 ORY91964.1 - 0.028 14.2 20.3 0.065 13.0 20.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) PRP1_N PF06424.12 ORY91964.1 - 0.031 14.7 8.5 0.04 14.3 8.5 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3584 PF12128.8 ORY91964.1 - 0.041 11.4 16.8 0.049 11.1 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 ORY91964.1 - 0.043 13.4 9.8 0.052 13.1 9.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit EzrA PF06160.12 ORY91964.1 - 0.061 11.5 21.8 0.047 11.9 7.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 ORY91964.1 - 0.074 13.1 28.4 0.088 12.9 26.1 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.13 ORY91964.1 - 0.081 13.0 21.6 0.12 12.4 21.6 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.8 ORY91964.1 - 0.1 12.7 21.1 0.26 11.4 20.8 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding V-ATPase_C PF03223.15 ORY91964.1 - 0.11 11.9 7.2 0.04 13.3 3.7 1.8 1 1 1 2 2 2 0 V-ATPase subunit C BLOC1_2 PF10046.9 ORY91964.1 - 0.11 12.8 18.1 1.9 8.8 13.5 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HemX PF04375.14 ORY91964.1 - 0.13 11.6 14.4 3.2 6.9 14.4 2.1 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 ORY91964.1 - 0.15 11.3 22.0 0.55 9.5 13.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 ORY91964.1 - 0.19 12.3 22.7 0.18 12.4 10.3 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 ERM PF00769.19 ORY91964.1 - 0.21 11.4 33.7 0.27 11.0 33.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family JIP_LZII PF16471.5 ORY91964.1 - 0.23 11.7 19.7 0.045 13.9 7.4 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II UPF0242 PF06785.11 ORY91964.1 - 0.24 11.5 20.5 1.8 8.7 20.6 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Striatin PF08232.12 ORY91964.1 - 0.26 11.9 19.5 0.35 11.5 19.5 1.1 1 0 0 1 1 1 0 Striatin family TMPIT PF07851.13 ORY91964.1 - 0.26 10.5 13.7 0.62 9.3 13.7 1.7 1 0 0 1 1 1 0 TMPIT-like protein Rootletin PF15035.6 ORY91964.1 - 0.27 11.3 19.5 0.37 10.8 19.5 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FPP PF05911.11 ORY91964.1 - 0.3 9.2 23.0 0.36 9.0 23.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Flagellin_C PF00700.21 ORY91964.1 - 0.32 11.4 3.0 0.38 11.1 1.5 1.8 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Uso1_p115_C PF04871.13 ORY91964.1 - 0.33 11.3 28.8 0.38 11.1 27.1 1.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_DNA_bd PF12329.8 ORY91964.1 - 0.39 10.7 27.9 0.55 10.3 13.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 ORY91964.1 - 0.4 10.1 18.2 0.76 9.2 18.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_GPO PF05929.11 ORY91964.1 - 0.53 9.9 14.9 0.75 9.4 14.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tup_N PF08581.10 ORY91964.1 - 0.55 10.6 19.9 1.4 9.3 5.6 2.2 1 1 1 2 2 2 0 Tup N-terminal DegS PF05384.11 ORY91964.1 - 0.63 9.5 18.1 0.086 12.3 6.7 2.2 1 1 0 2 2 2 0 Sensor protein DegS KLRAQ PF10205.9 ORY91964.1 - 0.65 10.3 18.5 1 9.6 13.1 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein WXG100 PF06013.12 ORY91964.1 - 0.73 10.1 15.3 4.9 7.5 4.5 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG SlyX PF04102.12 ORY91964.1 - 0.87 10.3 17.0 2.6 8.7 7.2 2.3 1 1 1 2 2 2 0 SlyX DUF4472 PF14739.6 ORY91964.1 - 0.89 10.3 22.2 0.047 14.4 14.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) bZIP_1 PF00170.21 ORY91964.1 - 0.92 9.7 24.6 2.6 8.2 6.5 3.1 1 1 2 3 3 3 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 ORY91964.1 - 1 9.6 23.4 0.87 9.8 9.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.19 ORY91964.1 - 1.1 8.9 26.4 0.69 9.6 10.4 2.4 1 1 1 2 2 2 0 GrpE Laminin_II PF06009.12 ORY91964.1 - 1.2 9.1 14.3 5.1 7.1 14.4 1.8 1 1 0 1 1 1 0 Laminin Domain II AAA_11 PF13086.6 ORY91964.1 - 1.5 8.5 12.7 2.1 8.1 12.7 1.1 1 0 0 1 1 1 0 AAA domain PI_PP_I PF18363.1 ORY91964.1 - 1.6 8.9 4.9 0.27 11.4 1.3 1.6 2 0 0 2 2 1 0 Phosphoinositide phosphatase insertion domain Atg14 PF10186.9 ORY91964.1 - 1.6 7.7 17.2 5.4 6.0 17.1 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 ORY91964.1 - 1.6 8.5 22.2 1.7 8.5 19.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 ORY91964.1 - 1.7 8.8 13.1 2.6 8.2 13.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 ORY91964.1 - 2 8.5 17.1 0.34 10.9 7.4 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 ORY91964.1 - 2.1 7.1 17.0 2.6 6.8 15.9 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CLZ PF16526.5 ORY91964.1 - 2.2 8.7 22.8 4.6 7.7 7.2 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec34 PF04136.15 ORY91964.1 - 2.3 8.1 14.2 1.8 8.5 10.8 2.0 1 1 1 2 2 2 0 Sec34-like family ZapB PF06005.12 ORY91964.1 - 2.4 8.6 29.8 0.14 12.6 6.6 2.9 1 1 2 3 3 2 0 Cell division protein ZapB FAM76 PF16046.5 ORY91964.1 - 2.5 7.4 11.6 3.4 6.9 11.6 1.2 1 0 0 1 1 1 0 FAM76 protein CHDCT2 PF08074.11 ORY91964.1 - 2.5 8.2 8.0 3.5 7.8 8.0 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain FlxA PF14282.6 ORY91964.1 - 2.5 8.1 18.8 14 5.7 18.7 2.0 1 1 0 1 1 1 0 FlxA-like protein DUF745 PF05335.13 ORY91964.1 - 2.8 7.6 18.7 1.2 8.8 14.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) V_ATPase_I PF01496.19 ORY91964.1 - 2.8 5.7 13.2 4.3 5.1 13.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T3SSipB PF16535.5 ORY91964.1 - 3 8.3 16.6 12 6.3 16.6 1.8 1 1 0 1 1 1 0 Type III cell invasion protein SipB HAUS-augmin3 PF14932.6 ORY91964.1 - 3.1 7.3 22.2 8.6 5.9 21.8 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 TraF_2 PF13729.6 ORY91964.1 - 3.1 7.1 6.8 2.7 7.3 1.0 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Jnk-SapK_ap_N PF09744.9 ORY91964.1 - 3.3 7.9 28.7 17 5.6 28.7 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 MPS2 PF17060.5 ORY91964.1 - 3.6 6.8 13.3 0.29 10.4 8.3 1.7 2 0 0 2 2 1 0 Monopolar spindle protein 2 Baculo_PEP_C PF04513.12 ORY91964.1 - 3.8 7.6 6.4 8.5 6.4 6.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.8 ORY91964.1 - 4 6.8 26.6 15 4.9 26.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DASH_Hsk3 PF08227.11 ORY91964.1 - 4.1 7.8 8.0 1.1 9.6 0.8 2.6 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like KxDL PF10241.9 ORY91964.1 - 4.1 7.7 16.1 0.82 10.0 4.8 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein FapA PF03961.13 ORY91964.1 - 4.3 5.8 17.2 7.2 5.1 17.1 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 ORY91964.1 - 4.3 6.9 22.8 12 5.4 22.8 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlaC_arch PF05377.11 ORY91964.1 - 4.6 7.7 19.5 7.7 7.0 4.7 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 ORY91964.1 - 4.7 7.0 14.4 1.5 8.6 4.6 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TolA_bind_tri PF16331.5 ORY91964.1 - 4.8 7.3 18.4 43 4.3 0.1 3.0 1 1 2 3 3 3 0 TolA binding protein trimerisation DUF812 PF05667.11 ORY91964.1 - 5.3 5.8 25.3 13 4.5 25.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) EAP30 PF04157.16 ORY91964.1 - 5.5 6.2 12.1 3.9 6.7 10.3 1.5 1 1 1 2 2 2 0 EAP30/Vps36 family Metal_resist PF13801.6 ORY91964.1 - 6.2 7.0 9.9 15 5.8 5.5 2.3 1 1 1 2 2 2 0 Heavy-metal resistance Nup54 PF13874.6 ORY91964.1 - 6.9 6.8 17.2 11 6.2 16.9 1.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF16 PF01519.16 ORY91964.1 - 9.7 6.7 15.9 1.5 9.4 10.9 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Nup88 PF10168.9 ORY91964.1 - 9.8 3.8 17.1 14 3.4 17.1 1.2 1 0 0 1 1 1 0 Nuclear pore component MFS_1 PF07690.16 ORY91965.1 - 2.1e-35 122.3 29.6 2.8e-35 121.9 29.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_transf_34 PF05637.12 ORY91966.1 - 1.2e-18 67.8 0.1 9.2e-18 64.8 0.1 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORY91966.1 - 4.4e-05 23.2 0.0 0.00011 21.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 ORY91966.1 - 0.0011 19.0 0.3 0.0027 17.7 0.3 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF269 PF03270.13 ORY91966.1 - 0.053 13.6 0.4 0.11 12.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF269 Siva PF05458.12 ORY91967.1 - 1.3e-10 41.2 12.1 1.6e-10 40.9 12.1 1.3 1 0 0 1 1 1 1 Cd27 binding protein (Siva) C1_2 PF03107.16 ORY91967.1 - 0.011 16.1 8.2 0.011 16.1 8.2 3.0 2 1 0 2 2 2 0 C1 domain zf-B_box PF00643.24 ORY91967.1 - 0.015 15.4 24.3 0.056 13.6 10.1 3.0 1 1 1 2 2 2 0 B-box zinc finger Pox_VLTF3 PF04947.14 ORY91967.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Myotub-related PF06602.14 ORY91968.1 - 5.1e-149 496.0 0.3 6.2e-149 495.7 0.3 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 ORY91968.1 - 0.0013 18.6 0.1 0.0032 17.3 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY91968.1 - 0.0055 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY91968.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family MTS PF05175.14 ORY91969.1 - 3.1e-09 36.6 0.0 4.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORY91969.1 - 6.4e-07 29.3 0.1 1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY91969.1 - 1.9e-06 28.5 0.6 4.1e-06 27.4 0.5 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY91969.1 - 0.0003 20.3 0.6 0.00047 19.7 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 ORY91969.1 - 0.00032 20.3 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 ORY91969.1 - 0.00049 19.8 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmC_N PF17827.1 ORY91969.1 - 0.0022 18.5 0.2 0.0066 17.0 0.2 1.9 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 ORY91969.1 - 0.0081 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ORY91969.1 - 0.01 15.5 0.3 0.027 14.1 0.1 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 ORY91969.1 - 0.015 16.0 0.1 0.041 14.5 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 ORY91969.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_12 PF08242.12 ORY91969.1 - 0.029 15.1 0.1 0.068 13.9 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain CRA PF06589.11 ORY91970.1 - 0.041 14.0 6.2 0.087 12.9 6.2 1.5 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) EphA2_TM PF14575.6 ORY91970.1 - 0.63 11.0 1.7 1.2 10.1 1.7 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 ORY91971.1 - 1.1e-60 205.2 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91971.1 - 4.5e-38 131.0 0.0 5.4e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY91971.1 - 0.0013 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY91971.1 - 0.0034 16.2 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 ORY91971.1 - 0.0053 16.4 0.2 0.011 15.4 0.1 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 ORY91971.1 - 0.012 15.5 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY91971.1 - 0.035 13.4 0.0 0.084 12.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Ecl1 PF12855.7 ORY91972.1 - 4.1e-10 41.1 39.9 1.6e-09 39.2 39.9 1.8 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 ORY91972.1 - 0.0011 19.0 0.5 0.0023 18.0 0.5 1.5 1 0 0 1 1 1 1 MYND finger PARM PF17061.5 ORY91972.1 - 0.49 10.5 27.6 0.71 10.0 27.6 1.2 1 0 0 1 1 1 0 PARM DMT_YdcZ PF04657.13 ORY91974.1 - 2.8e-31 108.6 12.3 3.8e-31 108.2 12.3 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ TRAP_alpha PF03896.16 ORY91974.1 - 0.2 10.8 0.2 17 4.5 0.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit APG5 PF04106.12 ORY91975.1 - 4e-52 177.1 0.0 5.6e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 ADH_zinc_N_2 PF13602.6 ORY91976.1 - 6.2e-16 59.7 0.0 1.1e-15 58.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY91976.1 - 7.3e-13 48.6 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY91976.1 - 1.1e-09 38.2 0.0 2.2e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 ORY91976.1 - 0.00081 19.8 0.4 0.0016 18.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF2855 PF11017.8 ORY91976.1 - 0.0031 17.3 0.1 0.0081 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2855) adh_short PF00106.25 ORY91976.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 ORY91976.1 - 0.026 14.7 0.7 0.2 11.8 0.7 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ORY91976.1 - 0.064 14.0 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Eno-Rase_NADH_b PF12242.8 ORY91976.1 - 0.069 12.9 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 ORY91976.1 - 0.076 13.3 0.2 0.46 10.7 0.2 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ATG16 PF08614.11 ORY91977.1 - 0.008 16.4 15.8 0.008 16.4 15.8 4.3 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 ORY91977.1 - 0.49 9.4 15.5 1.5 7.8 15.5 1.9 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LCD1 PF09798.9 ORY91977.1 - 1 7.8 16.8 1.9 6.9 16.8 1.5 1 0 0 1 1 1 0 DNA damage checkpoint protein UPF0242 PF06785.11 ORY91977.1 - 1.1 9.3 25.9 3.5 7.7 25.9 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CN_hydrolase PF00795.22 ORY91978.1 - 7.6e-27 94.3 0.0 1.1e-26 93.7 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Sec62 PF03839.16 ORY91979.1 - 6.8e-49 166.3 6.0 1.8e-48 164.9 6.0 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 ORY91979.1 - 0.43 9.7 4.9 0.6 9.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) DUF2458 PF10454.9 ORY91980.1 - 7.3e-07 29.0 6.4 7.3e-07 29.0 6.4 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2458) ABC2_membrane PF01061.24 ORY91981.1 - 0.13 11.7 9.9 0.19 11.1 9.9 1.4 1 1 0 1 1 1 0 ABC-2 type transporter DUF3367 PF11847.8 ORY91981.1 - 0.15 9.9 0.9 0.17 9.7 0.9 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase HLH PF00010.26 ORY91985.1 - 6.4e-18 64.5 0.0 6.4e-18 64.5 0.0 2.5 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Pox_A_type_inc PF04508.12 ORY91985.1 - 0.041 13.7 2.0 0.16 11.8 0.1 2.7 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Carn_acyltransf PF00755.20 ORY91986.1 - 3.3e-206 686.4 0.0 3.8e-206 686.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PNP_UDP_1 PF01048.20 ORY91988.1 - 2.2e-40 138.4 0.0 2.5e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Amino_oxidase PF01593.24 ORY91990.1 - 3.1e-29 102.6 0.0 4.5e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY91990.1 - 1e-13 51.3 0.1 2.3e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY91990.1 - 2e-12 47.4 0.0 6.4e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY91990.1 - 4.4e-10 39.3 0.0 2.6e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY91990.1 - 9.4e-07 28.2 1.3 7.8e-06 25.2 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ORY91990.1 - 6.2e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY91990.1 - 2.8e-05 23.0 0.1 0.00047 19.0 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 ORY91990.1 - 0.00089 18.4 1.0 0.0031 16.6 0.4 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY91990.1 - 0.0016 19.0 2.2 0.023 15.2 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY91990.1 - 0.0016 18.5 1.7 0.071 13.1 0.2 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY91990.1 - 0.0056 16.0 0.1 0.0092 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 ORY91990.1 - 0.0067 16.1 0.2 0.013 15.2 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 ORY91990.1 - 0.012 14.4 1.0 0.45 9.3 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.25 ORY91990.1 - 0.017 14.6 0.3 0.03 13.8 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_7 PF13241.6 ORY91990.1 - 0.022 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 ORY91990.1 - 0.024 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GDI PF00996.18 ORY91990.1 - 0.029 12.9 0.0 2.8 6.4 0.0 2.3 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 ORY91990.1 - 0.038 13.2 0.1 0.087 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ORY91990.1 - 0.042 13.7 0.3 0.078 12.8 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY91990.1 - 0.046 14.0 0.1 0.093 13.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 ORY91990.1 - 0.094 11.7 2.3 0.11 11.5 0.1 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 ORY91990.1 - 0.14 11.7 0.3 0.4 10.2 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORY91990.1 - 0.21 11.5 0.1 0.51 10.3 0.0 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SQS_PSY PF00494.19 ORY91991.1 - 1.7e-54 185.1 5.1 2.4e-54 184.6 5.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase bZIP_1 PF00170.21 ORY91993.1 - 4e-11 42.9 5.0 5.4e-11 42.4 5.0 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY91993.1 - 4.4e-09 36.3 5.2 7.2e-09 35.6 5.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY91993.1 - 0.00097 19.6 3.1 0.0013 19.2 3.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor WD40_alt PF14077.6 ORY91993.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif Pro_CA PF00484.19 ORY91994.1 - 7.7e-49 166.0 1.3 1.3e-48 165.2 1.3 1.4 1 0 0 1 1 1 1 Carbonic anhydrase TilS PF09179.11 ORY91995.1 - 0.037 14.5 0.1 0.037 14.5 0.1 1.8 2 0 0 2 2 2 0 TilS substrate binding domain zf-C2H2 PF00096.26 ORY91997.1 - 3.5e-24 83.8 19.9 1.7e-06 28.1 0.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY91997.1 - 3.4e-18 65.2 28.7 2e-06 27.9 0.0 5.8 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY91997.1 - 2.3e-08 34.2 30.8 0.015 16.1 0.7 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORY91997.1 - 0.0051 17.4 14.1 0.72 10.5 0.1 4.3 4 1 1 5 5 4 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY91997.1 - 0.017 15.4 13.7 7.9 6.9 0.1 5.1 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY91997.1 - 0.057 13.8 4.4 36 4.9 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY91997.1 - 0.084 13.2 0.3 0.084 13.2 0.3 3.4 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORY91997.1 - 0.089 12.6 0.4 0.089 12.6 0.4 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type Ogr_Delta PF04606.12 ORY91997.1 - 0.59 10.2 7.2 17 5.5 0.0 4.1 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger zf-CGNR PF11706.8 ORY91997.1 - 0.6 10.0 13.4 0.57 10.1 0.3 4.5 5 0 0 5 5 5 0 CGNR zinc finger zf-C2H2_aberr PF17017.5 ORY91997.1 - 1.9 8.6 5.8 8.9 6.4 0.1 3.5 1 1 3 4 4 4 0 Aberrant zinc-finger Aha1_N PF09229.11 ORY91998.1 - 1.6e-40 138.5 1.2 3.2e-40 137.5 1.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORY91998.1 - 2.1e-19 69.9 0.5 4.6e-19 68.9 0.5 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Kinesin_assoc PF16183.5 ORY91998.1 - 0.036 14.2 0.3 0.057 13.6 0.3 1.3 1 0 0 1 1 1 0 Kinesin-associated Folliculin PF11704.8 ORY92000.1 - 7.3e-32 110.8 0.0 1.1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Pyr_redox_2 PF07992.14 ORY92004.1 - 1e-69 235.0 4.9 1.6e-69 234.4 4.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY92004.1 - 2.3e-42 143.7 0.1 6.6e-42 142.2 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY92004.1 - 1.3e-20 73.7 6.3 2.6e-18 66.3 2.4 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY92004.1 - 2e-13 50.3 3.8 8.5e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY92004.1 - 1.3e-11 44.2 3.0 1.9e-10 40.4 0.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORY92004.1 - 5.1e-11 42.6 0.5 5.1e-11 42.6 0.5 2.6 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY92004.1 - 4.8e-08 32.5 10.4 1.8e-07 30.6 0.9 3.6 4 0 0 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 ORY92004.1 - 4.6e-07 30.0 2.5 0.00063 19.9 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY92004.1 - 1.4e-06 27.8 4.3 4.7e-05 22.7 0.0 2.7 2 1 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ORY92004.1 - 2.9e-06 26.8 6.4 0.0081 15.4 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ORY92004.1 - 7.7e-06 24.9 11.6 0.00014 20.7 0.5 4.0 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY92004.1 - 6.9e-05 22.2 3.7 0.007 15.7 0.3 2.7 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 ORY92004.1 - 9.7e-05 21.7 0.2 0.18 10.9 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY92004.1 - 0.019 14.5 13.6 0.2 11.2 0.2 4.0 3 1 1 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ORY92004.1 - 0.034 14.0 0.9 0.034 14.0 0.9 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY92004.1 - 0.6 9.7 3.5 0.63 9.6 0.4 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 ORY92004.1 - 6.5 5.7 7.4 1.7 7.6 0.5 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein ODC_AZ PF02100.17 ORY92006.1 - 2.1e-08 34.1 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Pox_F15 PF04596.12 ORY92006.1 - 0.15 11.8 0.7 0.26 11.1 0.3 1.4 2 0 0 2 2 2 0 Poxvirus protein F15 DUF1644 PF07800.12 ORY92007.1 - 0.059 13.4 1.7 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) UvrB PF12344.8 ORY92007.1 - 0.074 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Ultra-violet resistance protein B ORF_12_N PF18042.1 ORY92007.1 - 0.18 12.3 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 ORF 12 gene product N-terminal TMEM247 PF15444.6 ORY92008.1 - 6.2 6.8 8.3 6.8 6.7 8.3 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 Rieske_2 PF13806.6 ORY92009.1 - 4e-19 68.5 0.0 1.4e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 ORY92009.1 - 8.3e-19 67.7 8.6 2.5e-14 53.4 5.6 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 ORY92009.1 - 2e-14 53.4 0.0 3.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske PF00355.26 ORY92009.1 - 7.1e-12 45.1 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 ORY92009.1 - 3.3e-11 42.9 0.0 8.7e-10 38.4 0.0 2.8 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain NIR_SIR_ferr PF03460.17 ORY92009.1 - 5e-11 42.3 0.0 1.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_2 PF07992.14 ORY92009.1 - 2.1e-09 37.0 0.0 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Oxidored_molyb PF00174.19 ORY92010.1 - 1.5e-56 190.7 0.0 2.9e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY92010.1 - 3e-44 150.4 0.0 6e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 ORY92010.1 - 8.9e-22 77.0 0.0 2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 ORY92010.1 - 2.8e-20 72.5 0.0 4.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY92010.1 - 3.2e-19 69.6 0.0 7.3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY92010.1 - 0.019 15.1 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain MFS_1 PF07690.16 ORY92011.1 - 7.3e-39 133.7 23.4 9.5e-39 133.3 15.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY92011.1 - 2e-07 29.7 2.0 4.1e-07 28.7 2.0 1.7 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Aa_trans PF01490.18 ORY92012.1 - 1.4e-54 185.4 26.4 1.6e-53 181.9 26.4 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY92012.1 - 9.9e-06 24.6 14.0 9.9e-06 24.6 14.0 2.2 1 1 1 2 2 2 2 Amino acid permease Copper-fist PF00649.18 ORY92013.1 - 5.3e-11 41.8 1.3 5.3e-11 41.8 1.3 2.8 3 0 0 3 3 3 2 Copper fist DNA binding domain FapA PF03961.13 ORY92014.1 - 2.9 6.4 4.8 3.6 6.1 4.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 ORY92014.1 - 3.4 6.4 10.0 2.8 6.7 9.0 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter ATP-synt_C PF00137.21 ORY92015.1 - 1.2e-34 118.4 33.7 9e-24 83.6 14.0 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 ORY92015.1 - 0.41 10.4 5.9 1.1 9.0 1.4 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain GerA PF03323.13 ORY92015.1 - 5.3 5.4 6.6 8 4.8 0.6 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Alginate_lyase PF05426.12 ORY92016.1 - 6e-17 62.1 6.9 1.4e-16 60.9 3.0 2.8 2 1 0 2 2 2 1 Alginate lyase Acetyltransf_1 PF00583.25 ORY92019.1 - 1.2e-08 35.1 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY92019.1 - 2.4e-05 24.3 0.0 0.00028 20.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY92019.1 - 0.00033 21.0 0.0 0.00081 19.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4834 PF16118.5 ORY92019.1 - 0.078 14.0 0.5 0.62 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Sld5 PF05916.11 ORY92020.1 - 3.7e-09 37.0 0.0 5.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein RFX_DNA_binding PF02257.15 ORY92021.1 - 3e-16 59.8 0.0 5.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain PRP3 PF08572.10 ORY92022.1 - 9.9e-77 257.6 13.1 9.9e-77 257.6 13.1 1.9 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 ORY92022.1 - 7.3e-40 136.4 1.0 7.3e-40 136.4 1.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) Totivirus_coat PF05518.11 ORY92022.1 - 2.3 6.2 8.1 3.6 5.5 8.1 1.3 1 0 0 1 1 1 0 Totivirus coat protein RNase_T PF00929.24 ORY92023.1 - 1.6e-08 35.3 0.0 3.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Ndc1_Nup PF09531.10 ORY92023.1 - 7.5 5.1 8.7 11 4.6 8.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Trypsin PF00089.26 ORY92024.1 - 2.7e-21 76.4 0.0 4.1e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY92024.1 - 3.6e-09 37.7 0.0 6.7e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Macoilin PF09726.9 ORY92025.1 - 3.6 6.0 6.5 4.8 5.6 6.5 1.3 1 0 0 1 1 1 0 Macoilin family Tom22 PF04281.13 ORY92026.1 - 3.4e-38 130.5 1.1 4.2e-38 130.2 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GvpG PF05120.12 ORY92026.1 - 0.079 13.0 1.7 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Gas vesicle protein G PBP1_TM PF14812.6 ORY92026.1 - 0.28 11.6 3.1 0.45 10.9 3.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DAHP_synth_1 PF00793.20 ORY92027.1 - 3.2e-104 347.7 0.0 3.8e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Rep_fac_C PF08542.11 ORY92028.1 - 1.2e-20 73.7 0.1 3.2e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ORY92028.1 - 3.2e-17 63.2 0.0 5.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORY92028.1 - 6.8e-14 52.0 0.0 1.1e-10 41.5 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 ORY92028.1 - 1.2e-08 35.1 0.0 2e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 ORY92028.1 - 4.9e-06 26.4 0.0 8.2e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 ORY92028.1 - 1.8e-05 24.6 0.1 5e-05 23.1 0.0 1.7 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 ORY92028.1 - 1.9e-05 25.1 0.0 4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 ORY92028.1 - 5.1e-05 23.1 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 ORY92028.1 - 5.4e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 ORY92028.1 - 8.8e-05 22.3 0.1 0.00054 19.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY92028.1 - 0.00032 20.7 0.0 0.00059 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY92028.1 - 0.00036 20.4 0.1 0.0031 17.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 ORY92028.1 - 0.00045 19.5 0.0 0.00067 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY92028.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 ORY92028.1 - 0.0012 19.2 2.2 0.65 10.3 0.1 3.1 2 1 1 3 3 3 1 AAA domain TniB PF05621.11 ORY92028.1 - 0.0013 18.2 0.0 1 8.7 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein AAA_19 PF13245.6 ORY92028.1 - 0.0044 17.4 0.0 0.0096 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ORY92028.1 - 0.012 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY92028.1 - 0.015 15.3 0.1 0.08 12.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 ORY92028.1 - 0.043 13.6 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 ORY92028.1 - 0.045 13.1 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 ORY92028.1 - 0.058 13.4 0.0 1.6 8.7 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY92028.1 - 0.087 12.6 0.2 0.79 9.5 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 ORY92028.1 - 0.095 12.1 0.4 4.2 6.8 0.0 2.3 1 1 1 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 ORY92028.1 - 0.16 11.5 0.2 0.78 9.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain TPR_6 PF13174.6 ORY92028.1 - 0.33 11.7 1.4 12 6.8 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_11 PF13086.6 ORY92029.1 - 2.4e-65 220.9 2.0 4.2e-65 220.1 2.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORY92029.1 - 1.2e-61 207.8 0.0 2.7e-61 206.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 ORY92029.1 - 2.2e-40 138.6 5.9 3.9e-40 137.8 5.9 1.4 1 0 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.6 ORY92029.1 - 9.3e-09 35.8 0.0 3.9e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY92029.1 - 3.1e-08 33.6 0.3 0.00017 21.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ORY92029.1 - 6.8e-07 29.3 0.4 0.0047 16.7 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 ORY92029.1 - 8.5e-06 25.5 0.4 8.8e-05 22.2 0.4 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 ORY92029.1 - 0.0038 17.2 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY92029.1 - 0.0073 16.6 0.4 0.036 14.3 0.4 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 ORY92029.1 - 0.01 15.6 1.4 0.11 12.2 1.4 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 ORY92029.1 - 0.95 9.8 3.4 3.1 8.1 0.2 3.2 3 1 0 3 3 3 0 AAA ATPase domain MCM PF00493.23 ORY92031.1 - 8.9e-105 348.7 0.0 1.3e-104 348.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY92031.1 - 6.6e-32 110.0 1.3 1.2e-31 109.2 1.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY92031.1 - 2.9e-20 72.5 3.4 6.9e-20 71.3 3.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY92031.1 - 7.5e-16 58.6 1.2 2e-15 57.3 1.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY92031.1 - 3e-07 30.0 0.1 7.8e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY92031.1 - 4.4e-06 26.7 0.0 2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 ORY92031.1 - 0.013 15.4 0.2 0.051 13.4 0.2 2.1 1 0 0 1 1 1 0 AAA lid domain AAA PF00004.29 ORY92031.1 - 0.014 15.9 2.0 0.87 10.0 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 ORY92031.1 - 0.025 14.4 0.0 0.11 12.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FKBP26_C PF18046.1 ORY92031.1 - 0.089 12.9 0.6 0.34 11.1 0.4 2.1 2 0 0 2 2 2 0 FKBP26_C-terminal Sigma54_activat PF00158.26 ORY92031.1 - 0.12 12.0 0.0 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Spidroin_MaSp PF11260.8 ORY92031.1 - 0.13 12.5 0.3 0.4 11.0 0.1 1.9 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 ApoLp-III PF07464.11 ORY92031.1 - 0.29 11.2 1.8 0.6 10.2 1.8 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_16 PF13191.6 ORY92031.1 - 0.97 9.8 3.8 4.5 7.6 0.0 3.2 3 1 1 4 4 4 0 AAA ATPase domain WD40 PF00400.32 ORY92032.1 - 1.3e-61 203.1 16.7 4.6e-10 39.9 0.5 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92032.1 - 1.9e-20 72.9 0.5 0.00072 19.8 0.0 5.9 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY92032.1 - 2e-10 40.0 3.6 0.0037 16.0 0.0 5.5 3 1 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY92032.1 - 1.1e-06 27.7 0.7 0.85 8.3 0.0 4.4 2 2 2 4 4 4 3 Nup133 N terminal like Ge1_WD40 PF16529.5 ORY92032.1 - 1.9e-05 23.8 4.7 0.071 12.0 1.1 3.8 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY92032.1 - 2.1e-05 24.5 0.1 0.31 10.9 0.1 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ORY92032.1 - 0.00053 18.6 0.1 1.6 7.2 0.0 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain LisH PF08513.11 ORY92032.1 - 0.00082 19.2 0.3 0.0022 17.9 0.3 1.7 1 0 0 1 1 1 1 LisH nos_propeller PF18764.1 ORY92032.1 - 0.011 15.6 0.1 25 4.9 0.0 3.6 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat DUF3362 PF11842.8 ORY92032.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) PALB2_WD40 PF16756.5 ORY92032.1 - 0.39 9.6 2.3 13 4.6 0.0 3.3 2 2 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 ORY92033.1 - 1.1e-65 221.7 0.0 1.8e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92033.1 - 9.5e-35 120.1 0.0 1.9e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 ORY92033.1 - 1.1e-18 66.8 26.9 5.2e-11 42.3 10.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 ORY92033.1 - 7.2e-14 51.7 24.5 5.3e-09 36.1 1.8 3.4 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 ORY92033.1 - 4e-10 40.2 1.4 2.4e-09 37.7 0.8 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 ORY92033.1 - 4e-06 27.1 0.0 7.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain FTA2 PF13095.6 ORY92033.1 - 0.0014 18.3 0.0 0.058 13.0 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORY92033.1 - 0.0082 15.5 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY92033.1 - 0.043 12.8 0.0 0.043 12.8 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain C1_2 PF03107.16 ORY92033.1 - 0.051 13.9 23.0 0.35 11.2 8.6 2.7 2 0 0 2 2 2 0 C1 domain Abhydrolase_1 PF00561.20 ORY92034.1 - 2.1e-14 53.8 0.0 3e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY92034.1 - 1e-06 28.2 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ribosomal_S18 PF01084.20 ORY92035.1 - 5.3e-24 84.2 0.0 1.5e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 Pkinase PF00069.25 ORY92036.1 - 1.1e-69 234.8 0.0 1.3e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92036.1 - 2.2e-33 115.6 0.0 4.2e-33 114.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY92036.1 - 0.00015 21.2 0.0 0.003 16.9 0.0 2.4 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY92036.1 - 0.0053 16.4 0.1 0.0082 15.8 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY92036.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY92036.1 - 0.045 13.7 0.0 0.31 10.9 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY92036.1 - 0.055 13.1 0.0 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Vac7 PF12751.7 ORY92037.1 - 7.7e-12 45.3 0.0 2e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Peptidase_M24 PF00557.24 ORY92038.1 - 2.2e-50 171.2 0.0 3.7e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY92038.1 - 2.7e-19 69.1 0.0 9.5e-19 67.3 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain PLDc_2 PF13091.6 ORY92039.1 - 1.6e-27 96.0 0.2 3e-27 95.1 0.2 1.5 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 ORY92039.1 - 0.00068 19.7 0.2 0.0021 18.1 0.2 1.9 1 0 0 1 1 1 1 Phospholipase D Active site motif FAM83 PF07894.12 ORY92039.1 - 0.0028 17.3 5.5 0.049 13.2 0.1 3.2 2 1 0 2 2 2 1 FAM83 A-H Regulator_TrmB PF11495.8 ORY92039.1 - 0.07 12.3 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Abhydrolase_6 PF12697.7 ORY92040.1 - 0.0013 19.4 0.0 0.0015 19.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY92040.1 - 0.0038 16.5 0.1 0.0048 16.2 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY92040.1 - 0.0055 16.5 0.1 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 ORY92040.1 - 0.043 13.9 0.0 0.092 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain DUF676 PF05057.14 ORY92040.1 - 0.066 12.7 0.1 0.17 11.4 0.0 2.0 1 1 1 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 ORY92040.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4974 PF16344.5 ORY92040.1 - 0.15 12.1 1.3 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) DEADboxA PF12343.8 ORY92041.1 - 0.06 13.9 1.5 0.094 13.3 1.5 1.2 1 0 0 1 1 1 0 Cold shock protein DEAD box A NADH_dh_m_C1 PF15088.6 ORY92042.1 - 0.055 13.1 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Dak1 PF02733.17 ORY92043.1 - 9.7e-09 34.5 0.6 1e-08 34.5 0.6 1.0 1 0 0 1 1 1 1 Dak1 domain Phage_fiber_2 PF03406.13 ORY92043.1 - 0.064 12.8 0.3 0.085 12.4 0.3 1.2 1 0 0 1 1 1 0 Phage tail fibre repeat Dak2 PF02734.17 ORY92044.1 - 3.1e-42 144.4 4.7 4.7e-42 143.8 4.7 1.3 1 0 0 1 1 1 1 DAK2 domain Dak1 PF02733.17 ORY92044.1 - 4.1e-27 94.9 0.0 8.5e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Dak1 domain Zn_clus PF00172.18 ORY92045.1 - 1e-05 25.5 7.1 2.1e-05 24.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mu-like_gpT PF10124.9 ORY92045.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage major head subunit gpT DUF104 PF01954.16 ORY92045.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 Arrestin_C PF02752.22 ORY92046.1 - 0.00091 19.7 0.0 0.0023 18.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Pex14_N PF04695.13 ORY92046.1 - 1.8 9.2 18.3 0.53 10.9 9.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Arrestin_N PF00339.29 ORY92047.1 - 8e-10 38.9 0.0 5.7e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SET PF00856.28 ORY92048.1 - 2e-07 31.6 8.0 2.1e-07 31.5 0.1 3.2 2 2 0 3 3 3 2 SET domain Mito_carr PF00153.27 ORY92050.1 - 1.4e-66 220.4 1.9 4.5e-22 77.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY92050.1 - 0.0041 16.3 0.1 2.5 7.2 0.0 2.9 3 0 0 3 3 3 2 Gammaproteobacterial serine protease Pkinase PF00069.25 ORY92051.1 - 2.6e-65 220.4 0.0 3.1e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92051.1 - 8.6e-31 107.2 0.0 1.5e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY92051.1 - 8.1e-05 21.7 0.1 0.00011 21.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY92051.1 - 0.068 12.8 0.2 0.3 10.7 0.1 1.9 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 ORY92051.1 - 0.086 12.7 2.1 0.15 11.9 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY92051.1 - 0.17 11.3 0.8 0.43 9.9 0.3 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 ORY92052.1 - 3.2e-44 151.3 8.1 3.2e-44 151.3 8.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY92052.1 - 3.3e-09 36.1 4.8 1.6e-08 33.9 4.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORY92052.1 - 0.0022 16.5 0.7 0.0033 15.9 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 ORY92052.1 - 0.0027 16.5 2.6 0.0057 15.5 2.6 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter KOG2701 PF09762.9 ORY92052.1 - 0.082 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Caps_synth_CapC PF14102.6 ORY92052.1 - 1.4 9.3 8.9 5.2 7.5 1.4 3.4 3 1 1 4 4 4 0 Capsule biosynthesis CapC SH3_1 PF00018.28 ORY92053.1 - 8.8e-10 38.0 0.0 1.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY92053.1 - 3.3e-07 30.1 0.0 6.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY92053.1 - 7.4e-07 28.8 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 ORY92053.1 - 0.14 12.5 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Totivirus_coat PF05518.11 ORY92053.1 - 0.58 8.1 4.2 0.77 7.7 4.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Ribosomal_S14 PF00253.21 ORY92054.1 - 7.4e-11 41.6 0.7 7.9e-11 41.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Copper-fist PF00649.18 ORY92055.1 - 2.2e-19 68.6 2.7 2.2e-19 68.6 2.7 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain XPG_I_2 PF12813.7 ORY92056.1 - 1.7e-07 31.0 0.0 1.6e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 XPG domain containing XPG_I PF00867.18 ORY92056.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY92056.1 - 0.078 13.5 0.0 0.27 11.8 0.0 1.9 1 1 0 1 1 1 0 XPG N-terminal domain Cyclin PF08613.11 ORY92058.1 - 3.3e-09 37.3 0.1 1.5e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_C_2 PF16899.5 ORY92058.1 - 0.1 13.0 0.5 0.25 11.7 0.4 1.7 1 1 0 1 1 1 0 Cyclin C-terminal domain Cyclin_N PF00134.23 ORY92058.1 - 0.12 12.1 1.9 1 9.1 1.9 2.2 1 1 0 1 1 1 0 Cyclin, N-terminal domain TIG PF01833.24 ORY92060.1 - 6e-12 45.5 2.1 1.6e-11 44.1 0.1 2.8 3 0 0 3 3 3 1 IPT/TIG domain Ank_4 PF13637.6 ORY92060.1 - 3.3e-09 37.1 0.2 1.3e-08 35.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY92060.1 - 1.5e-08 35.1 0.1 3.4e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY92060.1 - 1.1e-07 32.0 1.6 0.0004 20.6 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY92060.1 - 1.6e-07 31.0 0.2 0.047 14.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 ORY92060.1 - 5.2e-07 29.8 0.8 0.034 14.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat ATP-synt_ab PF00006.25 ORY92061.1 - 4.2e-71 239.0 0.0 5.8e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY92061.1 - 1.3e-46 158.1 0.1 2e-46 157.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY92061.1 - 3.3e-20 72.4 0.6 1.1e-19 70.7 0.6 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Caleosin PF05042.13 ORY92062.1 - 4.9e-10 39.6 0.0 3.8e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Caleosin related protein DUF4407 PF14362.6 ORY92062.1 - 0.16 11.3 1.9 0.23 10.8 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PMM PF03332.13 ORY92063.1 - 2.6e-109 364.2 0.2 2.9e-109 364.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 ORY92063.1 - 7e-06 26.0 0.0 0.0001 22.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 ORY92063.1 - 0.084 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase DUF600 PF04634.12 ORY92063.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF600 CreD PF06123.12 ORY92064.1 - 0.0041 16.0 0.9 0.0061 15.4 0.9 1.2 1 0 0 1 1 1 1 Inner membrane protein CreD TFIIA PF03153.13 ORY92064.1 - 0.2 11.6 25.3 0.24 11.3 25.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 ORY92065.1 - 1.1e-69 234.7 0.0 2.8e-69 233.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92065.1 - 1.4e-41 142.5 0.0 5.4e-41 140.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY92065.1 - 7.3e-07 29.3 0.0 0.00085 19.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY92065.1 - 0.0001 21.7 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY92065.1 - 0.00062 18.8 0.1 0.0018 17.3 0.1 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY92065.1 - 0.0026 17.1 0.6 0.0054 16.1 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY92065.1 - 0.0068 16.0 0.3 0.021 14.4 0.3 1.9 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 ORY92065.1 - 0.066 12.0 0.0 0.066 12.0 0.0 3.0 3 1 0 3 3 3 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 ORY92065.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Thaumatin PF00314.17 ORY92068.1 - 7.1e-49 166.3 16.0 3.7e-48 164.0 16.0 1.8 1 1 0 1 1 1 1 Thaumatin family TB2_DP1_HVA22 PF03134.19 ORY92069.1 - 5.9e-29 99.8 5.7 5.9e-29 99.8 5.7 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF2207 PF09972.9 ORY92069.1 - 0.0083 14.9 0.6 0.0099 14.7 0.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MINDY_DUB PF04424.13 ORY92070.1 - 6.8e-36 122.8 0.0 1.4e-35 121.8 0.0 1.5 1 1 0 1 1 1 1 MINDY deubiquitinase Glyoxalase PF00903.25 ORY92071.1 - 5.4e-21 75.1 0.0 6.8e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY92071.1 - 5.3e-08 33.1 0.0 2.4e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ORY92071.1 - 2.3e-06 27.6 0.2 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ORY92071.1 - 0.00038 21.2 0.0 0.00075 20.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 ORY92071.1 - 0.0053 16.8 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 CppA N-terminal Glyoxalase_3 PF13468.6 ORY92071.1 - 0.0054 16.9 0.0 0.093 12.8 0.0 2.0 1 1 1 2 2 2 2 Glyoxalase-like domain tRNA-synt_1b PF00579.25 ORY92072.1 - 5.9e-75 252.3 0.0 7e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 ORY92072.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 ORY92072.1 - 0.14 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 S4 domain zf-C2H2_10 PF16588.5 ORY92073.1 - 0.00021 20.9 2.8 0.00035 20.2 2.8 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 ORY92073.1 - 0.075 12.8 0.7 0.12 12.2 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_18 PF00704.28 ORY92074.1 - 5.8e-83 279.2 5.9 6.7e-83 279.0 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HSP90 PF00183.18 ORY92075.1 - 7.2e-234 777.4 32.3 9.3e-234 777.1 32.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORY92075.1 - 2.1e-14 54.0 0.1 4.8e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY92075.1 - 2.4e-10 40.4 0.1 7.7e-10 38.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S10 PF00450.22 ORY92075.1 - 0.076 12.4 0.4 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Serine carboxypeptidase Cofac_haem_bdg PF04187.13 ORY92075.1 - 5.9 6.8 5.7 1.1 9.2 0.3 2.5 2 2 1 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN HMG_box PF00505.19 ORY92076.1 - 5.2e-15 55.6 2.9 9.2e-15 54.8 2.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY92076.1 - 0.00015 22.2 1.5 0.00015 22.2 1.5 1.7 1 1 1 2 2 2 1 HMG-box domain Ribosomal_L29 PF00831.23 ORY92077.1 - 1.5e-15 56.9 4.1 1.5e-15 56.9 4.1 2.4 1 1 1 2 2 2 1 Ribosomal L29 protein DUF498 PF04430.14 ORY92078.1 - 1.7e-29 102.1 0.0 2.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) IIGP PF05049.13 ORY92079.1 - 2.8e-21 76.0 0.0 3.3e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 ORY92079.1 - 4.2e-07 30.0 0.0 5.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ORY92079.1 - 0.00024 21.3 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY92079.1 - 0.0038 17.6 0.0 0.005 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ORY92079.1 - 0.0068 15.9 0.0 0.0096 15.4 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ORY92079.1 - 0.0072 16.2 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 ORY92079.1 - 0.019 15.5 0.0 0.027 15.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 ORY92079.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 ORY92079.1 - 0.023 14.7 1.3 0.047 13.7 1.0 1.6 1 1 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 ORY92079.1 - 0.036 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 ORY92079.1 - 0.061 12.6 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 ORY92079.1 - 0.078 12.3 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 AIG1 family AAA_29 PF13555.6 ORY92079.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.6 ORY92079.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY92079.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY92079.1 - 0.18 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY92079.1 - 0.27 10.4 0.1 0.38 9.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Thiolase_N PF00108.23 ORY92080.1 - 1.8e-89 299.6 4.0 2.7e-89 299.0 4.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY92080.1 - 1.2e-41 141.2 0.9 1.2e-41 141.2 0.9 2.7 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY92080.1 - 7e-08 32.3 2.2 1.4e-05 24.8 0.2 3.0 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY92080.1 - 0.17 11.7 6.6 2.2 8.2 0.1 3.7 3 1 1 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UL42 PF17638.2 ORY92082.1 - 0.12 12.4 5.2 0.16 12.0 5.2 1.1 1 0 0 1 1 1 0 HCMV UL42 zf_C2H2_ZHX PF18387.1 ORY92082.1 - 0.17 11.6 1.7 0.28 10.9 1.7 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain PTR2 PF00854.21 ORY92083.1 - 1.6e-88 297.3 9.3 2.5e-88 296.6 9.3 1.3 1 0 0 1 1 1 1 POT family CCB1 PF12046.8 ORY92083.1 - 0.19 11.0 2.0 0.21 10.9 0.2 2.0 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B XPG_N PF00752.17 ORY92084.1 - 7.9e-15 55.2 0.0 2.1e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORY92084.1 - 1.1e-14 54.6 0.1 3.2e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 ORY92084.1 - 0.003 18.1 0.8 0.07 13.7 0.0 2.8 2 1 1 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold BLOC1_2 PF10046.9 ORY92084.1 - 0.017 15.4 1.8 0.034 14.4 1.8 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_UL3 PF03369.13 ORY92084.1 - 0.22 12.1 2.1 0.54 10.8 2.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL3 protein GatB_N PF02934.15 ORY92085.1 - 8.6e-106 353.3 0.0 1.1e-105 352.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ORY92085.1 - 1.6e-32 112.5 0.0 3e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 GatB domain DAO PF01266.24 ORY92086.1 - 6.4e-52 177.3 0.1 8.7e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ORY92086.1 - 2.7e-45 153.3 0.1 7.1e-45 151.9 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 ORY92086.1 - 8.9e-09 34.9 1.9 0.00013 21.3 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ORY92086.1 - 1.7e-07 31.0 1.4 1.9e-05 24.2 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 ORY92086.1 - 6.1e-05 22.3 0.2 0.062 12.4 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ORY92086.1 - 0.00029 20.2 0.2 0.0047 16.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY92086.1 - 0.00099 18.4 0.0 0.071 12.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ORY92086.1 - 0.0012 19.0 0.6 0.0058 16.8 0.4 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY92086.1 - 0.024 13.9 0.1 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY92086.1 - 0.034 14.7 0.7 0.62 10.7 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY92086.1 - 0.039 12.7 0.9 0.073 11.8 0.9 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 ORY92086.1 - 0.044 13.7 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY92086.1 - 0.14 12.4 0.5 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Kelch_4 PF13418.6 ORY92087.1 - 0.00089 19.2 0.0 0.0078 16.2 0.0 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY92087.1 - 0.0097 15.9 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 1 Kelch motif AGA2 PF17366.2 ORY92087.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 A-agglutinin-binding subunit Aga2 Kelch_3 PF13415.6 ORY92087.1 - 0.13 12.6 0.6 3.5 8.0 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain KIAA1328 PF15369.6 ORY92087.1 - 1.3 8.8 3.5 14 5.4 3.4 2.2 1 1 0 1 1 1 0 Uncharacterised protein KIAA1328 6PF2K PF01591.18 ORY92088.1 - 6.4e-69 231.6 0.0 1.1e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY92088.1 - 8e-24 84.4 0.0 1.5e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY92088.1 - 0.00066 19.9 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF202 PF02656.15 ORY92091.1 - 1.1e-21 77.0 1.2 1.1e-21 77.0 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2675 PF11247.8 ORY92091.1 - 0.026 14.7 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) CI-B14_5a PF07347.12 ORY92091.1 - 0.45 10.4 4.0 0.74 9.7 4.0 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Peptidase_S8 PF00082.22 ORY92092.1 - 7.6e-40 137.0 5.3 1.2e-39 136.3 5.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY92092.1 - 3.9e-08 33.9 0.0 7.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sel1 PF08238.12 ORY92093.1 - 4e-58 192.5 114.1 3.2e-06 27.6 0.1 28.2 29 2 0 29 29 29 15 Sel1 repeat TPR_19 PF14559.6 ORY92093.1 - 8.8e-10 39.0 67.6 0.0023 18.4 0.4 12.7 12 1 0 12 12 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY92093.1 - 5.7e-09 35.4 42.9 0.73 10.0 0.0 13.1 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY92093.1 - 2.8e-08 34.0 84.9 0.0038 17.5 2.6 15.8 15 3 2 18 18 17 7 Tetratricopeptide repeat TPR_2 PF07719.17 ORY92093.1 - 5e-06 26.2 84.3 0.19 11.9 4.2 19.0 21 0 0 21 21 18 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY92093.1 - 1.5e-05 25.2 52.0 0.54 10.5 0.2 12.4 10 3 2 12 12 12 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORY92093.1 - 6.1e-05 23.6 97.8 0.0041 17.7 2.2 15.2 12 2 3 15 15 15 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORY92093.1 - 0.00021 21.2 49.4 1.5 9.2 0.1 14.6 17 1 0 17 17 16 2 Tetratricopeptide repeat TPR_3 PF07720.12 ORY92093.1 - 0.0036 17.3 0.6 0.0036 17.3 0.6 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY92093.1 - 0.0081 16.7 0.1 0.048 14.3 0.1 15.2 17 0 0 17 17 16 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY92093.1 - 0.0089 15.8 59.5 1.6 8.7 0.2 15.4 16 1 0 16 16 16 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY92093.1 - 0.012 15.2 28.0 5.7 6.7 0.1 11.6 11 2 1 12 12 12 0 TPR repeat TPR_4 PF07721.14 ORY92093.1 - 0.11 13.2 0.1 0.11 13.2 0.1 10.8 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY92093.1 - 0.17 12.7 93.0 0.23 12.4 0.6 17.0 15 3 4 19 19 17 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY92093.1 - 0.26 11.2 53.2 1.2 9.1 0.5 12.0 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY92093.1 - 5.5 7.6 20.4 1.5e+02 3.1 0.1 10.6 12 1 1 14 14 10 0 Tetratricopeptide repeat DUF2225 PF09986.9 ORY92093.1 - 6.6 6.4 8.1 8.7 6.0 0.0 4.4 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) Hexokinase_2 PF03727.16 ORY92094.1 - 3.4e-66 223.1 0.0 4.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY92094.1 - 1.9e-59 200.9 0.0 3e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.32 ORY92095.1 - 1.5e-20 73.1 6.0 9.6e-05 23.1 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92095.1 - 8.8e-07 29.1 0.0 0.75 10.1 0.0 4.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY92095.1 - 0.0064 15.2 0.8 2 6.9 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 INTS5_C PF14838.6 ORY92096.1 - 9.8e-07 27.8 5.5 0.00015 20.6 0.1 3.0 3 0 0 3 3 3 3 Integrator complex subunit 5 C-terminus Peptidase_M56 PF05569.11 ORY92097.1 - 0.12 11.5 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 FDC-SP PF15215.6 ORY92099.1 - 0.25 11.9 1.6 0.43 11.2 0.1 2.2 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide PPR_2 PF13041.6 ORY92100.1 - 2e-61 204.0 11.9 3.6e-14 52.7 0.0 9.8 8 4 4 12 12 11 8 PPR repeat family PPR_3 PF13812.6 ORY92100.1 - 3.4e-43 145.5 8.2 3.7e-13 49.3 0.1 8.2 7 1 0 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.20 ORY92100.1 - 8.1e-29 97.8 8.8 1.6e-05 24.8 0.0 10.1 12 0 0 12 12 12 6 PPR repeat PPR_1 PF12854.7 ORY92100.1 - 2.9e-26 90.8 1.7 4.5e-08 32.6 0.0 9.4 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 ORY92100.1 - 1e-19 70.8 6.7 1.1e-07 31.5 0.0 6.5 2 1 5 7 7 7 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORY92100.1 - 9.6e-07 29.2 6.2 0.0005 20.5 0.2 5.3 3 3 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORY92100.1 - 1.8e-06 28.3 0.7 0.71 10.8 0.0 5.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY92100.1 - 4.2e-05 24.0 0.0 1.4 9.5 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF4003 PF13170.6 ORY92100.1 - 0.002 17.6 3.3 1 8.7 0.1 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF4003) AEP1 PF17049.5 ORY92100.1 - 0.0027 16.9 0.3 3.5 6.6 0.1 3.8 2 2 2 4 4 4 1 ATPase expression protein 1 Questin_oxidase PF14027.6 ORY92100.1 - 0.022 14.3 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 Questin oxidase-like TPR_16 PF13432.6 ORY92100.1 - 0.052 14.2 1.8 1.2 9.9 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ENT PF03735.14 ORY92100.1 - 0.06 13.4 0.2 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 ENT domain Gag_spuma PF03276.14 ORY92100.1 - 0.067 11.6 0.3 0.86 8.0 0.0 2.0 2 0 0 2 2 2 0 Spumavirus gag protein YkuD_2 PF13645.6 ORY92100.1 - 0.095 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain FliT PF05400.13 ORY92100.1 - 0.13 13.1 1.7 0.67 10.8 0.3 2.6 2 0 0 2 2 2 0 Flagellar protein FliT DUF3446 PF11928.8 ORY92100.1 - 0.3 11.4 13.8 0.8 10.0 13.8 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain TPR_8 PF13181.6 ORY92100.1 - 0.53 10.6 1.9 4.9 7.6 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat SR-25 PF10500.9 ORY92100.1 - 6.8 6.2 14.7 12 5.4 14.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phage_holin_2_4 PF16082.5 ORY92101.1 - 0.29 10.9 1.1 0.61 9.9 1.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Melibiase_2 PF16499.5 ORY92102.1 - 9.5e-73 244.8 1.8 1.5e-72 244.2 1.8 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY92102.1 - 8e-13 48.3 0.7 9.2e-12 44.9 0.1 2.8 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY92102.1 - 1.6e-07 30.6 0.0 3.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Melibiase Glyco_hydro_30C PF17189.4 ORY92102.1 - 0.037 14.2 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain Raffinose_syn PF05691.12 ORY92102.1 - 0.066 11.0 0.0 0.11 10.3 0.0 1.3 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Pkinase PF00069.25 ORY92103.1 - 1.8e-69 234.0 0.0 3.1e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92103.1 - 1.5e-32 112.9 0.0 2.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY92103.1 - 8.5e-07 28.6 0.5 1.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY92103.1 - 0.0012 17.7 0.7 0.065 12.0 0.0 2.0 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 ORY92103.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY92103.1 - 0.46 9.4 5.1 2.1 7.2 5.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Cgr1 PF03879.14 ORY92104.1 - 1.8e-12 47.6 11.0 2.2e-12 47.3 11.0 1.1 1 0 0 1 1 1 1 Cgr1 family DUF4558 PF15104.6 ORY92104.1 - 0.02 14.9 5.3 0.026 14.6 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) DUF1682 PF07946.14 ORY92104.1 - 0.23 10.6 6.3 0.24 10.6 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ada3 PF10198.9 ORY92105.1 - 1e-31 109.8 5.2 1e-31 109.8 5.2 2.3 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 RdRP PF05183.12 ORY92106.1 - 2.9e-184 614.0 0.5 7.2e-184 612.7 0.2 1.7 2 0 0 2 2 2 1 RNA dependent RNA polymerase RRM_1 PF00076.22 ORY92106.1 - 0.00035 20.3 0.1 0.0035 17.1 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.21 ORY92106.1 - 0.034 14.3 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 Hsp20/alpha crystallin family RRM_1 PF00076.22 ORY92107.1 - 2.6e-38 129.7 0.0 1.6e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY92107.1 - 0.0034 17.4 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif TMEM70 PF06979.12 ORY92108.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex RBR PF17208.3 ORY92109.1 - 0.0015 19.2 1.6 0.003 18.2 1.6 1.5 1 0 0 1 1 1 1 RNA binding Region zf-C2H2 PF00096.26 ORY92109.1 - 0.03 14.8 11.5 0.12 12.9 0.1 3.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY92109.1 - 0.18 12.7 7.5 1.8 9.6 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Mnd1 PF03962.15 ORY92110.1 - 2e-28 98.4 0.8 2.8e-27 94.8 0.1 2.5 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 ORY92110.1 - 8.8e-11 41.7 4.2 2.4e-10 40.4 4.2 1.8 1 0 0 1 1 1 1 Leucine zipper with capping helix domain FUR PF01475.19 ORY92110.1 - 0.012 15.7 0.2 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Ferric uptake regulator family Lactamase_B_2 PF12706.7 ORY92111.1 - 8.3e-35 120.1 0.2 1.4e-34 119.4 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY92111.1 - 3.5e-16 59.5 0.0 4.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY92111.1 - 1.9e-05 24.7 0.1 0.017 15.2 0.1 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily LysM PF01476.20 ORY92112.1 - 1.8e-14 53.5 0.1 2.5e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 LysM domain HTH_7 PF02796.15 ORY92112.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase RolB_RolC PF02027.17 ORY92114.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.0 1 0 0 1 1 1 0 RolB/RolC glucosidase family zf-AN1 PF01428.16 ORY92115.1 - 0.33 11.1 3.2 0.4 10.9 0.3 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger DUF953 PF06110.11 ORY92115.1 - 0.43 10.2 2.2 0.56 9.8 2.0 1.5 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF953) AKAP2_C PF15304.6 ORY92116.1 - 0.0006 19.2 0.2 0.00061 19.2 0.2 1.0 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus BIRC6 PF12356.8 ORY92116.1 - 0.044 13.2 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Aconitase PF00330.20 ORY92117.1 - 6e-111 371.7 0.0 5.8e-110 368.4 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY92117.1 - 1.9e-20 73.5 0.0 3.9e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ORY92117.1 - 0.00068 18.4 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) zf-C2H2_2 PF12756.7 ORY92118.1 - 2.2e-37 127.4 9.5 3.5e-31 107.5 0.2 3.5 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY92118.1 - 1.4e-12 47.5 13.4 3.3e-08 33.6 4.4 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY92118.1 - 9.3e-08 32.2 7.1 1.2e-06 28.7 1.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-DBF PF07535.12 ORY92118.1 - 4.7e-05 23.4 0.7 4.7e-05 23.4 0.7 2.9 3 0 0 3 3 3 1 DBF zinc finger zf-LYAR PF08790.11 ORY92118.1 - 0.041 13.8 2.1 4.7 7.2 0.1 2.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 ORY92118.1 - 0.14 13.0 15.0 0.18 12.7 0.4 4.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY92118.1 - 1 10.0 7.2 2.8 8.6 0.7 2.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Asp PF00026.23 ORY92119.1 - 2.4e-90 303.2 0.2 2.7e-90 303.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY92119.1 - 1.5e-16 61.2 3.2 1.8e-08 34.9 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY92119.1 - 0.00016 21.5 0.1 0.002 17.9 0.1 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY92119.1 - 0.025 15.2 1.4 3.9 8.2 0.1 2.8 2 1 0 2 2 2 0 Aspartyl protease Ras PF00071.22 ORY92120.1 - 3.2e-56 189.4 0.0 3.8e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY92120.1 - 2.8e-33 114.7 0.0 5.6e-33 113.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY92120.1 - 1.2e-12 47.6 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY92120.1 - 9.8e-06 25.1 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY92120.1 - 4.9e-05 23.4 0.0 6.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY92120.1 - 0.00087 19.7 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 ORY92120.1 - 0.0049 16.4 0.0 0.0084 15.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY92120.1 - 0.016 15.1 0.1 0.33 10.9 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase MRP-L27 PF09809.9 ORY92121.1 - 2.4e-20 72.4 0.7 2.6e-20 72.3 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF1674 PF07896.12 ORY92122.1 - 1e-19 70.7 1.1 1e-19 70.7 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) COPIIcoated_ERV PF07970.12 ORY92123.1 - 1.3e-80 270.4 0.0 1.7e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY92123.1 - 7.1e-31 106.4 0.2 1.7e-30 105.2 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TcpE PF12648.7 ORY92125.1 - 0.21 12.1 0.7 2.2 8.9 0.7 2.0 1 1 0 1 1 1 0 TcpE family Ribosomal_L37ae PF01780.19 ORY92126.1 - 1.5e-42 143.6 11.6 1.6e-42 143.4 11.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 ORY92126.1 - 0.00069 19.5 1.0 0.0011 19.0 1.0 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 ORY92126.1 - 0.0015 18.6 2.7 0.0015 18.6 2.7 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 ORY92126.1 - 0.017 15.2 1.0 0.024 14.6 1.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 ORY92126.1 - 0.096 12.4 3.0 6 6.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 ORY92126.1 - 0.12 12.3 3.3 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 ORY92126.1 - 0.15 12.4 2.1 1.5 9.2 2.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 ORY92126.1 - 0.32 11.1 5.1 1.2 9.2 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger HalOD2 PF18547.1 ORY92126.1 - 0.5 10.3 5.3 4 7.4 1.1 2.3 1 1 1 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 ORY92126.1 - 0.85 9.6 6.2 0.24 11.3 1.9 2.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 ORY92126.1 - 4.9 7.8 6.7 4.2 8.0 0.7 2.3 1 1 0 2 2 2 0 Zinc-finger double domain Tropomyosin_1 PF12718.7 ORY92127.1 - 1.6e-34 119.1 38.1 1.6e-34 119.1 38.1 1.3 1 1 1 2 2 2 1 Tropomyosin like Tropomyosin PF00261.20 ORY92127.1 - 1.8e-07 30.8 37.7 8.4e-05 22.1 19.6 2.1 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.9 ORY92127.1 - 0.0015 18.5 37.0 0.0025 17.9 11.5 2.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 ORY92127.1 - 0.0017 18.6 40.4 0.0076 16.5 24.5 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 ORY92127.1 - 0.0099 15.9 18.4 0.25 11.4 0.3 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 ORY92127.1 - 0.023 14.8 40.6 0.41 10.7 21.5 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 ORY92127.1 - 0.05 14.0 30.1 0.91 9.9 15.6 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BORCS7 PF16088.5 ORY92127.1 - 0.057 13.7 1.1 0.057 13.7 1.1 2.6 2 2 1 3 3 2 0 BLOC-1-related complex sub-unit 7 GAS PF13851.6 ORY92127.1 - 0.062 12.6 38.2 0.17 11.2 38.2 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 ORY92127.1 - 0.072 11.3 32.9 0.13 10.4 32.9 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil HOOK PF05622.12 ORY92127.1 - 0.12 10.5 33.8 0.18 9.9 33.8 1.3 1 1 0 1 1 1 0 HOOK protein MscS_porin PF12795.7 ORY92127.1 - 0.17 11.4 39.3 0.2 11.2 31.4 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CEP63 PF17045.5 ORY92127.1 - 0.31 10.9 29.8 0.54 10.1 29.8 1.4 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa DUF724 PF05266.14 ORY92127.1 - 0.33 10.8 28.9 0.46 10.3 14.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) KLRAQ PF10205.9 ORY92127.1 - 0.38 11.0 28.8 0.81 10.0 7.9 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Lectin_N PF03954.14 ORY92127.1 - 0.46 10.2 20.8 0.057 13.2 3.9 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF812 PF05667.11 ORY92127.1 - 0.53 9.1 33.0 0.84 8.4 33.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 ORY92127.1 - 0.56 10.6 22.1 4.2 7.8 2.8 4.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Phage_GPO PF05929.11 ORY92127.1 - 0.63 9.6 26.8 0.23 11.0 14.2 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SHE3 PF17078.5 ORY92127.1 - 0.65 9.7 30.9 0.094 12.4 7.3 3.0 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 ORY92127.1 - 0.71 10.0 35.5 2 8.5 20.1 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 ORY92127.1 - 0.77 9.8 35.5 0.87 9.6 10.8 3.1 1 1 2 3 3 3 0 FlxA-like protein DUF5082 PF16888.5 ORY92127.1 - 0.77 10.0 27.9 0.39 11.0 18.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF2353 PF09789.9 ORY92127.1 - 0.8 9.0 30.8 0.067 12.5 15.9 1.9 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Laminin_II PF06009.12 ORY92127.1 - 1.4 9.0 24.9 0.95 9.5 8.8 2.2 1 1 1 2 2 2 0 Laminin Domain II MAD PF05557.13 ORY92127.1 - 1.5 7.1 34.8 1.8 6.8 34.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Fez1 PF06818.15 ORY92127.1 - 1.5 9.2 29.8 5.6 7.4 29.8 1.9 1 1 0 1 1 1 0 Fez1 HMMR_N PF15905.5 ORY92127.1 - 1.9 7.9 33.0 2.3 7.6 33.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 ORY92127.1 - 2 8.5 38.5 20 5.2 19.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 ORY92127.1 - 2.3 7.5 33.5 2.7 7.2 9.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 ORY92127.1 - 2.6 8.7 33.8 2 9.1 8.7 3.8 1 1 3 4 4 4 0 SlyX zf-C2H2_aberr PF17017.5 ORY92127.1 - 2.7 8.1 5.3 14 5.8 1.7 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger DivIC PF04977.15 ORY92127.1 - 2.7 7.8 39.5 0.98 9.2 6.8 4.1 2 1 1 3 3 2 0 Septum formation initiator DHR10 PF18595.1 ORY92127.1 - 3.8 7.6 42.8 0.1 12.6 13.6 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Transglut_prok PF09017.10 ORY92127.1 - 3.8 6.8 5.8 4.1 6.7 5.8 1.1 1 0 0 1 1 1 0 Microbial transglutaminase APG6_N PF17675.1 ORY92127.1 - 3.8 8.0 45.8 2.7 8.5 16.7 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 ORY92127.1 - 3.8 6.3 38.1 1 8.2 25.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 ORY92127.1 - 4.3 6.3 30.4 2.5 7.1 9.5 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZYG-11_interact PF05884.12 ORY92127.1 - 5 6.4 7.8 8.3 5.7 7.7 1.4 1 1 0 1 1 1 0 Interactor of ZYG-11 DUF4407 PF14362.6 ORY92127.1 - 5 6.4 27.6 64 2.7 27.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 ORY92127.1 - 5.5 7.5 44.6 0.9 10.0 7.1 4.0 1 1 1 2 2 1 0 Cell division protein ZapB BLOC1_2 PF10046.9 ORY92127.1 - 5.8 7.3 25.8 3 8.2 4.2 3.8 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMCO5 PF14992.6 ORY92127.1 - 6 6.3 31.6 16 4.9 31.6 1.8 1 1 0 1 1 1 0 TMCO5 family PRKG1_interact PF15898.5 ORY92127.1 - 6.3 7.8 32.9 0.95 10.4 16.0 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Cep57_CLD PF14073.6 ORY92127.1 - 7.2 6.6 36.4 8e+03 -3.3 36.4 2.7 1 1 0 1 1 0 0 Centrosome localisation domain of Cep57 BST2 PF16716.5 ORY92127.1 - 8 7.1 34.5 2.3 8.8 13.3 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF4200 PF13863.6 ORY92127.1 - 8.7 6.8 39.9 11 6.5 12.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Kelch_4 PF13418.6 ORY92128.1 - 2.2e-25 88.4 1.2 5.2e-09 36.0 0.1 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY92128.1 - 7.3e-25 86.5 0.1 1.2e-05 25.2 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 ORY92128.1 - 1.1e-23 82.7 0.3 3e-06 27.3 0.0 4.9 3 1 1 4 4 4 4 Kelch motif Kelch_2 PF07646.15 ORY92128.1 - 1.6e-18 65.9 0.3 0.00039 20.3 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORY92128.1 - 3.8e-15 55.2 0.3 0.00086 18.8 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 ORY92128.1 - 1e-12 48.0 5.5 0.016 15.5 0.0 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 ORY92128.1 - 6.8e-12 45.6 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 ORY92128.1 - 0.0031 17.6 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch PQQ_3 PF13570.6 ORY92128.1 - 0.32 11.5 2.3 20 5.8 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain zf-RanBP PF00641.18 ORY92131.1 - 3.3e-28 96.7 29.3 2.9e-11 42.5 1.1 4.5 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others RNase_T PF00929.24 ORY92131.1 - 1.2e-09 38.9 0.0 1.8e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 ORY92131.1 - 3.4e-05 23.6 0.0 0.00013 21.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HbrB PF08539.11 ORY92131.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 HbrB-like IlvB_leader PF08049.11 ORY92131.1 - 2.5 8.1 9.0 12 6.0 0.6 2.5 2 0 0 2 2 2 0 IlvB leader peptide DZR PF12773.7 ORY92131.1 - 9.9 6.3 28.5 1.6 8.8 2.8 3.7 2 2 1 3 3 3 0 Double zinc ribbon Sortilin-Vps10 PF15902.5 ORY92132.1 - 0 1299.6 13.4 1e-137 459.6 0.7 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 ORY92132.1 - 2e-130 431.8 36.1 7e-49 166.4 4.2 4.3 4 0 0 4 4 4 3 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 ORY92132.1 - 4.1e-07 29.0 68.0 0.14 12.2 0.7 15.2 15 0 0 15 15 15 7 BNR/Asp-box repeat PSII_BNR PF14870.6 ORY92132.1 - 0.001 18.4 0.1 0.001 18.4 0.1 6.4 8 1 0 8 8 8 1 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 ORY92132.1 - 0.0025 17.7 23.3 0.5 10.6 0.1 7.4 8 0 0 8 8 8 3 BNR-Asp box repeat CHB_HEX_C PF03174.13 ORY92132.1 - 0.21 11.6 12.1 10 6.2 0.1 6.8 9 0 0 9 9 9 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF4185 PF13810.6 ORY92132.1 - 2.9 7.1 22.4 9.7 5.3 0.2 7.8 7 2 2 9 9 9 0 Domain of unknown function (DUF4185) DUF4668 PF15701.5 ORY92135.1 - 0.038 13.8 9.5 0.13 12.1 0.9 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4668) ARD PF03079.14 ORY92136.1 - 5.4e-50 169.6 0.3 6.4e-50 169.4 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 ORY92136.1 - 4.3e-11 42.4 0.0 6.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORY92136.1 - 2.1e-06 27.7 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 ORY92136.1 - 0.004 16.8 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 ORY92136.1 - 0.019 14.7 0.0 0.039 13.6 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain 3-HAO PF06052.12 ORY92136.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.12 ORY92136.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 ORY92136.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Cupin Vps35 PF03635.17 ORY92137.1 - 0 1063.6 5.0 0 1063.4 5.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF758 PF05527.11 ORY92137.1 - 0.064 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Pannexin_like PF12534.8 ORY92137.1 - 0.15 11.2 0.5 0.26 10.4 0.5 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Zip PF02535.22 ORY92137.1 - 0.18 10.9 0.8 0.39 9.9 0.8 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 ORY92137.1 - 0.42 8.7 6.5 0.66 8.0 6.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 ORY92137.1 - 0.65 8.9 4.3 1.8 7.5 4.3 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4045 PF13254.6 ORY92137.1 - 2.6 7.6 14.3 3.9 7.0 12.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 ORY92137.1 - 7.7 6.3 20.1 18 5.1 20.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 ORY92137.1 - 9.9 4.5 18.6 15 3.9 18.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pribosyltran_N PF13793.6 ORY92138.1 - 4.8e-40 136.1 0.3 1.8e-36 124.6 0.0 3.1 2 1 1 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORY92138.1 - 9.1e-40 136.6 2.4 1.1e-33 116.9 0.7 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORY92138.1 - 4.2e-13 49.1 0.3 1.2e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORY92138.1 - 0.0026 17.2 0.1 0.0056 16.2 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RAB3GAP2_N PF14655.6 ORY92138.1 - 0.04 13.2 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Abhydrolase_1 PF00561.20 ORY92139.1 - 4.7e-56 190.3 0.0 6.6e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY92139.1 - 0.0044 17.6 0.1 0.0059 17.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORY92139.1 - 0.17 12.0 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Choline_kinase PF01633.20 ORY92140.1 - 1.3e-53 181.8 0.0 1.9e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 ORY92140.1 - 1.4e-16 61.2 0.9 2.2e-16 60.5 0.9 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DHHC PF01529.20 ORY92142.1 - 8.2e-21 74.5 2.7 9.9e-21 74.2 2.7 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Zf_RING PF16744.5 ORY92142.1 - 0.035 14.2 3.0 0.053 13.6 3.0 1.2 1 0 0 1 1 1 0 KIAA1045 RING finger DUF3916 PF13079.6 ORY92142.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) Tom7 PF08038.12 ORY92143.1 - 0.16 11.6 3.2 0.31 10.7 3.2 1.5 1 0 0 1 1 1 0 TOM7 family Cullin PF00888.22 ORY92144.1 - 1.8e-165 552.1 18.5 2.4e-165 551.7 18.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY92144.1 - 7.2e-24 83.6 0.9 2.1e-23 82.1 0.9 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-C2H2_aberr PF17017.5 ORY92144.1 - 0.38 10.9 6.4 0.87 9.7 0.1 3.2 3 0 0 3 3 3 0 Aberrant zinc-finger Fungal_trans PF04082.18 ORY92145.1 - 4.5e-10 39.0 0.0 1.8e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY92145.1 - 1e-08 35.1 10.8 3.1e-08 33.6 10.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKA2 PF16740.5 ORY92145.1 - 0.00071 19.3 0.2 0.015 15.1 0.1 2.6 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF948 PF06103.11 ORY92145.1 - 0.34 11.2 1.0 0.9 9.8 1.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PHM7_cyt PF14703.6 ORY92145.1 - 0.38 11.0 4.8 0.56 10.4 0.2 2.8 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DASH_Dad2 PF08654.10 ORY92145.1 - 2.1 8.8 5.3 1.4 9.4 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad2 AA_kinase PF00696.28 ORY92146.1 - 6.9e-40 137.2 0.2 1.2e-39 136.4 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORY92146.1 - 3.4e-11 43.0 1.6 1e-10 41.4 1.0 2.1 2 0 0 2 2 2 1 PUA domain UL16 PF17622.2 ORY92146.1 - 0.0082 15.8 0.1 0.019 14.6 0.1 1.5 1 1 0 1 1 1 1 Viral unique long protein 16 Pkinase PF00069.25 ORY92147.1 - 1.7e-71 240.7 0.0 2.4e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92147.1 - 1.8e-38 132.3 0.0 2.6e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY92147.1 - 3.2e-09 36.5 0.0 1.2e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY92147.1 - 0.0032 17.4 3.5 0.0038 17.2 0.2 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family KA1 PF02149.19 ORY92147.1 - 0.005 16.6 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.22 ORY92147.1 - 0.0057 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Arteri_nucleo PF01481.16 ORY92147.1 - 0.049 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Haspin_kinase PF12330.8 ORY92147.1 - 0.057 12.3 0.2 0.12 11.3 0.2 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY92147.1 - 0.48 9.2 5.1 0.13 11.0 0.2 2.4 2 1 0 2 2 2 0 Fungal protein kinase HLH PF00010.26 ORY92148.1 - 1.9e-18 66.1 0.6 5.3e-18 64.7 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2572 PF10833.8 ORY92148.1 - 0.1 12.3 1.2 0.22 11.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) V_ATPase_I PF01496.19 ORY92148.1 - 0.55 8.1 4.8 0.86 7.4 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DTHCT PF08070.11 ORY92148.1 - 1.5 9.6 9.5 27 5.6 5.2 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF702 PF05142.12 ORY92148.1 - 7 7.1 7.9 2 8.9 3.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) SLC35F PF06027.12 ORY92149.1 - 9.1e-65 219.1 12.4 1.1e-64 218.9 12.4 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 ORY92149.1 - 1.4e-09 37.3 0.2 2.2e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 ORY92149.1 - 1.5e-07 31.6 27.0 6e-05 23.2 11.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Pox_P21 PF05313.12 ORY92149.1 - 0.00051 19.7 0.6 0.0016 18.1 0.6 1.8 1 0 0 1 1 1 1 Poxvirus P21 membrane protein Dynamin_M PF01031.20 ORY92150.1 - 5.6e-102 340.8 0.9 1.6e-101 339.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORY92150.1 - 9e-56 188.5 0.3 2.1e-55 187.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 ORY92150.1 - 1.2e-30 105.5 8.2 1.2e-30 105.5 8.2 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY92150.1 - 0.00018 21.6 0.1 0.00069 19.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY92150.1 - 0.097 12.4 8.4 1.6 8.3 0.2 3.0 3 0 0 3 3 3 0 AAA ATPase domain LXG PF04740.12 ORY92150.1 - 0.099 12.3 1.7 0.68 9.6 0.0 2.7 3 0 0 3 3 3 0 LXG domain of WXG superfamily W2 PF02020.18 ORY92150.1 - 0.89 9.7 3.8 3.9 7.7 3.8 2.1 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Acyltransferase PF01553.21 ORY92152.1 - 2.3e-16 59.6 0.0 4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF624 PF04854.14 ORY92152.1 - 0.0035 17.4 1.0 0.059 13.5 1.4 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF624 PrgI PF12666.7 ORY92152.1 - 0.093 13.5 1.2 0.24 12.1 1.2 1.7 1 0 0 1 1 1 0 PrgI family protein KBP_C PF12309.8 ORY92152.1 - 0.095 12.2 0.9 0.13 11.7 0.9 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal FA_desaturase PF00487.24 ORY92152.1 - 0.13 12.1 5.5 0.22 11.3 5.5 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Ribosomal_S27e PF01667.17 ORY92153.1 - 6e-28 96.3 2.0 8.2e-28 95.9 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORY92153.1 - 0.00082 18.8 3.1 0.0013 18.2 3.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Prok-RING_1 PF14446.6 ORY92153.1 - 0.04 13.9 2.2 0.063 13.2 2.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.21 ORY92153.1 - 0.042 14.1 0.9 0.062 13.5 0.9 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 ORY92153.1 - 0.095 12.7 3.2 0.088 12.8 1.9 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_4 PF13717.6 ORY92153.1 - 0.13 12.2 2.1 3.5 7.6 2.1 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Glutaredoxin PF00462.24 ORY92154.1 - 1.5e-23 82.8 0.0 2.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 ORY92154.1 - 0.00027 21.3 0.2 0.00035 20.9 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 ORY92154.1 - 0.00039 20.4 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 ORY92154.1 - 0.00097 19.6 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 ORY92154.1 - 0.0026 18.1 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 ORY92154.1 - 0.0031 17.3 0.3 0.034 13.9 0.2 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY92154.1 - 0.0075 16.5 0.3 0.61 10.2 0.3 2.1 1 1 1 2 2 2 1 Thioredoxin GST_N_2 PF13409.6 ORY92154.1 - 0.026 14.8 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 ORY92154.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein MFS_1 PF07690.16 ORY92155.1 - 3.2e-18 65.8 58.5 1.5e-09 37.2 16.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY92155.1 - 3.5e-05 22.4 26.1 5.8e-05 21.7 25.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acyl-CoA_dh_1 PF00441.24 ORY92156.1 - 3.4e-42 144.2 0.3 5.5e-42 143.5 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY92156.1 - 8.9e-24 83.4 0.0 1.9e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY92156.1 - 4.7e-23 81.2 0.0 9.7e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY92156.1 - 1.7e-18 67.4 0.0 4.1e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY92156.1 - 8.8e-10 39.0 0.1 1.4e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Snf7 PF03357.21 ORY92157.1 - 1.6e-18 66.9 13.7 2.2e-18 66.4 13.7 1.2 1 0 0 1 1 1 1 Snf7 Cu_amine_oxidN1 PF07833.11 ORY92157.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain GrpE PF01025.19 ORY92157.1 - 3.2 7.4 11.8 0.41 10.3 5.0 2.2 2 0 0 2 2 2 0 GrpE Hydrolase_6 PF13344.6 ORY92158.1 - 2.7e-24 85.2 0.0 1.3e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY92158.1 - 1.3e-21 76.4 0.0 5.4e-21 74.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY92158.1 - 0.0011 19.3 0.0 2.3 8.5 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY92158.1 - 0.013 15.6 0.0 0.088 12.9 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase APC_r PF05923.12 ORY92158.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 APC repeat WD40 PF00400.32 ORY92159.1 - 1.5e-14 54.1 0.3 2.7e-05 24.9 0.0 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92159.1 - 5e-08 33.1 0.0 0.014 15.7 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY92159.1 - 0.0088 15.4 0.0 2.8 7.2 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain Utp8 PF10395.9 ORY92159.1 - 0.085 11.3 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Ammonium_transp PF00909.21 ORY92160.1 - 1.3e-122 409.4 24.0 1.5e-122 409.2 24.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family zf-C2H2 PF00096.26 ORY92161.1 - 4.8e-15 55.1 24.8 3.2e-06 27.3 2.5 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY92161.1 - 6.3e-14 51.7 22.5 1.9e-07 31.2 2.7 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY92161.1 - 4.7e-08 32.9 10.9 0.00084 19.3 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY92161.1 - 2.8e-07 30.8 25.6 0.0074 17.0 1.4 4.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY92161.1 - 2.1e-06 27.8 8.7 0.056 13.8 0.3 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY92161.1 - 0.0015 18.9 10.7 0.078 13.4 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-CCHC_2 PF13696.6 ORY92161.1 - 0.055 13.3 0.8 0.11 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle C1_4 PF07975.12 ORY92161.1 - 1.8 8.8 5.1 0.87 9.9 1.0 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HE PF16278.5 ORY92161.1 - 5.2 7.6 7.3 4.7 7.7 1.8 3.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TFIIA_gamma_N PF02268.16 ORY92162.1 - 1.6e-25 88.8 0.1 2.2e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 ORY92162.1 - 2.6e-25 88.3 1.0 3.6e-25 87.8 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF572 PF04502.13 ORY92163.1 - 2.2e-78 264.2 13.9 4e-78 263.3 13.1 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 ORY92163.1 - 0.039 14.0 2.8 1.4 9.0 0.5 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF4240 PF14024.6 ORY92163.1 - 0.068 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) HypA PF01155.19 ORY92163.1 - 0.28 11.2 1.6 0.71 9.9 0.4 2.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 ORY92163.1 - 0.35 10.8 2.0 5.9 6.9 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 ORY92163.1 - 0.39 10.3 2.4 3.9 7.1 0.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-NADH-PPase PF09297.11 ORY92163.1 - 0.61 9.8 2.6 2.2 8.0 0.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RPN2_C PF18004.1 ORY92164.1 - 3e-55 186.5 7.8 5e-55 185.8 7.8 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 ORY92164.1 - 6.7e-41 136.7 23.2 2.3e-07 30.9 0.0 8.4 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORY92164.1 - 3.6e-20 72.1 4.3 1.4e-13 51.0 0.2 4.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 ORY92164.1 - 7.4e-05 22.7 0.7 1.2 9.6 0.1 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 ORY92164.1 - 0.0012 19.3 4.2 0.24 11.9 0.1 5.2 4 2 2 6 6 6 1 HEAT-like repeat PHD20L1_u1 PF16660.5 ORY92164.1 - 0.045 14.5 1.5 0.12 13.2 1.5 1.7 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 Arm PF00514.23 ORY92164.1 - 0.077 13.1 0.0 51 4.1 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF913 PF06025.12 ORY92164.1 - 0.45 9.4 2.6 0.42 9.5 0.7 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 ORY92164.1 - 0.98 9.7 11.2 3.1 8.1 8.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HEAT_PBS PF03130.16 ORY92164.1 - 1 10.2 3.0 19 6.3 0.1 4.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat ABC_membrane PF00664.23 ORY92165.1 - 1.6e-123 411.7 33.2 3.5e-65 220.4 15.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY92165.1 - 1.4e-72 242.6 0.0 3.6e-35 121.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY92165.1 - 1.1e-14 54.5 1.9 2e-07 30.7 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY92165.1 - 1e-07 32.3 0.4 0.0026 18.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY92165.1 - 1.2e-07 32.3 0.6 0.018 15.4 0.1 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORY92165.1 - 2.6e-06 27.0 1.0 0.1 12.4 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORY92165.1 - 2.8e-06 26.4 0.5 0.012 14.5 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA PF00004.29 ORY92165.1 - 2.7e-05 24.6 4.1 0.1 13.1 0.7 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY92165.1 - 4.2e-05 23.5 0.0 0.31 10.9 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 ORY92165.1 - 6.3e-05 22.8 1.5 0.91 9.2 0.1 4.0 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORY92165.1 - 0.00021 20.6 0.1 0.48 9.7 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin SbcCD_C PF13558.6 ORY92165.1 - 0.00029 21.0 4.3 0.7 10.2 0.7 4.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 ORY92165.1 - 0.00046 19.8 0.0 0.36 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 ORY92165.1 - 0.0032 17.6 0.0 3.6 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 ORY92165.1 - 0.0032 17.4 0.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 ORY92165.1 - 0.0055 16.8 0.0 1.6 8.8 0.0 3.0 2 0 0 2 2 2 1 Helicase HerA, central domain G-alpha PF00503.20 ORY92165.1 - 0.0065 15.7 0.0 0.72 8.9 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_15 PF13175.6 ORY92165.1 - 0.0085 15.8 0.0 6.5 6.3 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 ORY92165.1 - 0.0087 15.7 0.0 0.95 9.0 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 ORY92165.1 - 0.012 15.6 0.0 1.5 8.9 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 ORY92165.1 - 0.032 14.3 0.0 9.9 6.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 ORY92165.1 - 0.045 14.1 0.0 6.6 7.2 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 ORY92165.1 - 0.047 13.4 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY92165.1 - 0.048 13.9 0.0 6.4 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORY92165.1 - 0.066 12.4 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dala_Dala_lig_N PF01820.21 ORY92165.1 - 0.16 12.4 1.4 2.7 8.5 0.0 2.8 3 0 0 3 3 2 0 D-ala D-ala ligase N-terminus AAA_23 PF13476.6 ORY92165.1 - 0.39 11.2 7.4 11 6.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain Usp PF00582.26 ORY92165.1 - 0.79 10.2 9.4 0.076 13.5 2.5 2.7 3 0 0 3 3 2 0 Universal stress protein family GCD14 PF08704.10 ORY92166.1 - 9.4e-89 297.3 0.4 7.6e-87 291.1 0.4 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORY92166.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORY92166.1 - 0.00078 19.3 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 ORY92166.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.6 ORY92166.1 - 0.017 16.2 0.0 0.033 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fasciclin PF02469.22 ORY92168.1 - 2.6e-32 111.7 11.3 2.7e-19 69.6 1.2 4.2 4 0 0 4 4 4 4 Fasciclin domain ECH_1 PF00378.20 ORY92169.1 - 1.6e-80 270.1 0.9 1.9e-80 269.8 0.9 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY92169.1 - 4.2e-33 115.3 1.1 2.2e-31 109.6 0.6 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORY92169.1 - 0.0011 19.0 0.4 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.16 ORY92169.1 - 0.17 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase SET PF00856.28 ORY92170.1 - 2.4e-10 41.1 0.0 3.1e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 SET domain Apt1 PF10351.9 ORY92172.1 - 1.3e-121 406.8 4.5 4.3e-121 405.1 4.5 1.9 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 ORY92172.1 - 2.6e-110 369.6 10.0 4.7e-110 368.7 10.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 ORY92172.1 - 4.3e-37 127.6 0.0 1.1e-36 126.4 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 ORY92172.1 - 2.3e-33 115.3 0.0 5.5e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 ORY92172.1 - 3.2e-20 72.7 0.0 2.9e-19 69.7 0.0 2.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain SR-25 PF10500.9 ORY92172.1 - 0.27 10.8 7.2 0.89 9.1 7.2 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PMI_typeI PF01238.21 ORY92173.1 - 1.1e-121 406.5 0.0 1.6e-121 406.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I Uteroglobin PF01099.17 ORY92173.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Uteroglobin family Hydrolase_6 PF13344.6 ORY92174.1 - 1.7e-31 108.3 0.1 4.2e-31 107.0 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY92174.1 - 5.2e-18 64.9 0.0 1.8e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY92174.1 - 2.6e-13 50.8 0.1 8.3e-13 49.1 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY92174.1 - 2.3e-09 37.6 0.0 0.00028 21.0 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF853 PF05872.12 ORY92174.1 - 0.0011 17.7 0.0 0.0022 16.7 0.0 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) Hydrolase_3 PF08282.12 ORY92174.1 - 0.022 14.5 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Forkhead PF00250.18 ORY92175.1 - 9.3e-38 128.4 0.1 2.2e-37 127.2 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 ORY92175.1 - 4.6e-12 46.1 0.0 8.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 ORY92175.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 FHA domain Linker_histone PF00538.19 ORY92175.1 - 0.076 13.4 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family Fcf1 PF04900.12 ORY92176.1 - 3.9e-37 126.6 0.7 3.9e-37 126.6 0.7 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 ORY92176.1 - 2.7e-11 43.8 0.1 5.6e-11 42.8 0.0 1.5 2 0 0 2 2 2 1 PIN like domain DUF3464 PF11947.8 ORY92176.1 - 2.1 8.1 5.6 0.31 10.8 2.1 1.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 HEAT_2 PF13646.6 ORY92178.1 - 1.6e-21 76.5 2.1 2.2e-07 31.2 0.1 8.1 7 3 3 10 10 10 5 HEAT repeats HEAT PF02985.22 ORY92178.1 - 9.3e-20 69.0 13.9 0.00034 20.6 0.3 11.5 13 0 0 13 13 13 5 HEAT repeat HEAT_EZ PF13513.6 ORY92178.1 - 2.6e-17 62.9 15.3 2.2e-06 28.0 0.3 9.8 6 2 3 9 9 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY92178.1 - 2.6e-11 43.9 0.5 2.7e-06 27.9 0.0 6.0 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY92178.1 - 1.3e-10 41.5 0.2 3.3e-05 24.0 0.1 4.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 ORY92178.1 - 4.1e-10 39.4 0.1 2.7e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 ORY92178.1 - 2.6e-08 33.9 0.3 1.6 8.6 0.0 7.1 8 0 0 8 8 8 2 Domain of unknown function (DUF3385) CLASP_N PF12348.8 ORY92178.1 - 7.1e-07 29.0 0.0 0.15 11.6 0.0 4.5 3 1 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 ORY92178.1 - 1.7e-06 27.4 2.1 0.03 13.4 0.2 4.1 2 1 2 4 4 4 2 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 ORY92178.1 - 7.4e-06 25.8 0.0 2.3 7.9 0.0 4.8 3 2 2 5 5 5 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 ORY92178.1 - 2.7e-05 23.5 1.0 0.012 14.8 0.0 4.3 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 ORY92178.1 - 5.9e-05 21.8 6.6 0.009 14.6 0.0 5.0 5 2 0 5 5 5 1 Adaptin N terminal region Tti2 PF10521.9 ORY92178.1 - 8.3e-05 22.3 0.1 1.3 8.5 0.0 4.4 4 1 1 5 5 5 1 Tti2 family RTP1_C1 PF10363.9 ORY92178.1 - 0.001 19.2 1.0 0.53 10.5 0.1 4.8 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 ORY92178.1 - 0.048 13.7 7.0 18 5.6 0.1 5.2 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Gcn1_N PF12074.8 ORY92178.1 - 0.11 11.8 0.0 3.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal CTD_bind PF04818.13 ORY92178.1 - 0.14 13.0 0.1 18 6.2 0.0 4.5 6 0 0 6 6 4 0 RNA polymerase II-binding domain. Cohesin_HEAT PF12765.7 ORY92178.1 - 0.15 12.4 0.1 1.5 9.2 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PhoU PF01895.19 ORY92178.1 - 0.51 10.8 3.2 3.7 8.1 1.1 3.1 2 0 0 2 2 2 0 PhoU domain Tti2 PF10521.9 ORY92179.1 - 3e-21 76.2 0.0 4.3e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Tti2 family DUF3384 PF11864.8 ORY92179.1 - 0.02 13.8 0.0 0.67 8.8 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3384) Adaptin_N PF01602.20 ORY92179.1 - 0.15 10.6 0.3 0.66 8.5 0.2 1.9 1 1 0 1 1 1 0 Adaptin N terminal region Aa_trans PF01490.18 ORY92180.1 - 1.7e-88 297.1 35.1 2e-88 296.8 35.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 ORY92181.1 - 4.2e-22 78.5 40.6 4.9e-20 71.7 33.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Fibrinogen_BP PF08017.11 ORY92182.1 - 5.3e-12 44.9 45.3 7.8e-12 44.3 45.3 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein ACT PF01842.25 ORY92182.1 - 0.14 11.9 4.1 19 5.1 0.1 3.9 3 0 0 3 3 3 0 ACT domain DUF4041 PF13250.6 ORY92182.1 - 0.47 10.4 5.0 5.7 6.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Pectinesterase PF01095.19 ORY92183.1 - 1.8e-57 194.4 4.6 2.3e-57 194.0 4.6 1.1 1 0 0 1 1 1 1 Pectinesterase HGTP_anticodon PF03129.20 ORY92184.1 - 2e-22 79.2 0.0 3.3e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORY92184.1 - 2.6e-06 27.5 0.0 7.1e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Fe-S_biosyn PF01521.20 ORY92186.1 - 1.3e-15 57.5 0.0 1.3e-14 54.3 0.0 2.0 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Phage_sheath_1N PF17481.2 ORY92186.1 - 0.018 15.5 0.0 0.027 14.9 0.0 1.3 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Sel1 PF08238.12 ORY92187.1 - 1.1e-17 64.1 33.7 3.5e-06 27.5 1.9 8.3 9 0 0 9 9 9 5 Sel1 repeat TPR_5 PF12688.7 ORY92187.1 - 0.041 14.1 0.9 0.041 14.1 0.9 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_14 PF13428.6 ORY92187.1 - 0.49 11.3 26.3 1.3 10.1 3.9 6.5 5 3 3 8 8 8 0 Tetratricopeptide repeat mRNA_cap_enzyme PF01331.19 ORY92188.1 - 1.8e-51 174.8 0.0 2.4e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ORY92188.1 - 2.1e-31 108.8 0.0 3.7e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 ORY92188.1 - 3.6e-11 43.1 0.0 2.6e-06 27.2 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 ORY92188.1 - 0.047 14.0 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA ligase Arf PF00025.21 ORY92189.1 - 1.9e-46 157.7 0.4 2.3e-46 157.4 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY92189.1 - 6.3e-21 74.6 0.0 7.8e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY92189.1 - 9.8e-18 64.5 0.0 1.5e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY92189.1 - 1.8e-10 40.6 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY92189.1 - 8.7e-10 38.3 0.6 8e-07 28.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 ORY92189.1 - 3.6e-09 36.7 0.0 5.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY92189.1 - 4.9e-09 35.9 0.1 5.8e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORY92189.1 - 0.0019 17.7 0.1 0.055 13.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY92189.1 - 0.0047 17.0 0.2 0.57 10.2 0.2 2.2 1 1 1 2 2 2 1 Dynamin family cobW PF02492.19 ORY92189.1 - 0.0091 15.6 0.1 0.86 9.2 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY92189.1 - 0.014 15.7 0.1 0.33 11.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY92189.1 - 0.045 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 ORY92189.1 - 0.055 12.9 0.0 6 6.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 ORY92189.1 - 0.057 12.9 1.1 0.14 11.7 0.1 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 ORY92189.1 - 0.1 13.2 0.1 0.21 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY92189.1 - 0.12 12.9 0.4 0.23 12.0 0.4 1.6 1 1 0 1 1 1 0 ABC transporter NAD_binding_10 PF13460.6 ORY92191.1 - 3.2e-16 59.7 0.0 5.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY92191.1 - 1.5e-12 47.6 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY92191.1 - 2.7e-12 46.7 0.0 6.4e-12 45.4 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY92191.1 - 1.3e-11 44.1 0.0 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY92191.1 - 1e-08 34.7 0.0 4e-07 29.4 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 ORY92191.1 - 2.8e-07 30.9 0.1 1.6e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 ORY92191.1 - 4.9e-06 25.9 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 ORY92191.1 - 3.9e-05 23.2 0.0 8.5e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 ORY92191.1 - 7.3e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 ORY92191.1 - 0.0014 18.2 0.1 0.006 16.2 0.0 1.8 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 ORY92191.1 - 0.0059 17.2 0.0 0.17 12.5 0.0 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORY92191.1 - 0.054 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 ORY92191.1 - 0.055 12.6 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 ORY92191.1 - 0.063 13.2 0.0 0.46 10.4 0.0 2.2 1 1 0 1 1 1 0 KR domain NGP1NT PF08153.12 ORY92192.1 - 2.2e-54 183.1 0.2 4e-54 182.3 0.2 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 ORY92192.1 - 5e-17 62.0 0.1 6.4e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY92192.1 - 7.5e-06 25.6 0.0 9.7e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 ORY92192.1 - 0.00017 21.1 0.1 0.047 13.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 ORY92192.1 - 0.0015 18.6 4.3 4.1 7.4 0.0 4.4 3 1 2 5 5 5 2 Dynamin family RsgA_GTPase PF03193.16 ORY92192.1 - 0.0026 17.7 0.0 0.0061 16.5 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 ORY92192.1 - 0.011 15.3 0.0 0.54 9.8 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain YL1 PF05764.13 ORY92192.1 - 0.16 12.0 15.0 0.33 11.0 15.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 ORY92192.1 - 8.9 4.5 12.5 14 3.8 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4112 PF13430.6 ORY92193.1 - 9.8e-39 131.9 0.7 1.3e-38 131.4 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) RhoGAP PF00620.27 ORY92194.1 - 1.6e-47 161.2 0.0 5.4e-47 159.4 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY92194.1 - 2.3e-14 53.4 33.2 1.2e-08 35.1 7.1 3.4 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 ORY92194.1 - 7.3e-09 35.4 4.7 7.3e-09 35.4 4.7 4.1 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 ORY92194.1 - 0.0062 16.8 0.9 0.0062 16.8 0.9 3.8 4 0 0 4 4 4 1 C1 domain Pro_isomerase PF00160.21 ORY92196.1 - 3.7e-49 167.0 0.2 6.3e-49 166.3 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 ORY92196.1 - 3.4e-12 45.5 6.4 0.00018 21.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY92196.1 - 8e-10 38.1 6.9 0.00041 20.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY92196.1 - 3.2e-07 29.9 3.0 0.00015 21.4 0.8 3.0 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 ORY92196.1 - 4.4e-07 29.6 6.3 0.047 13.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY92196.1 - 1.1e-06 29.2 3.9 0.00056 20.5 1.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY92196.1 - 0.00025 21.3 0.5 0.24 11.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY92196.1 - 0.0064 17.0 6.9 4.7 8.1 0.1 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY92196.1 - 0.0077 16.4 0.2 0.046 13.9 0.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 ORY92196.1 - 0.0086 16.1 0.3 0.0086 16.1 0.3 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain DUF5113 PF17140.4 ORY92196.1 - 0.03 14.1 0.3 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_19 PF14559.6 ORY92196.1 - 0.095 13.2 5.2 1.6 9.3 0.8 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY92196.1 - 0.1 13.5 0.4 6.3 7.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 ORY92196.1 - 0.11 12.5 2.2 0.71 9.9 2.2 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) GFO_IDH_MocA_C PF02894.17 ORY92196.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain LRR_4 PF12799.7 ORY92197.1 - 3.8e-11 43.0 7.0 0.23 11.9 0.0 7.7 8 1 1 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY92197.1 - 4e-11 42.0 16.9 0.43 10.7 0.0 10.4 11 0 0 11 11 11 5 Leucine Rich repeat F-box-like PF12937.7 ORY92197.1 - 3.2e-10 39.7 1.1 3.2e-10 39.7 1.1 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY92197.1 - 0.00058 19.7 3.1 0.0013 18.5 0.4 3.1 2 0 0 2 2 2 1 F-box domain TruB_N PF01509.18 ORY92198.1 - 7e-46 156.3 0.0 9.9e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ORY92198.1 - 6.9e-08 32.5 0.1 2.4e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain DUF4448 PF14610.6 ORY92199.1 - 3.6e-05 23.6 0.3 8.5e-05 22.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2062 PF09835.9 ORY92199.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) MAP17 PF15807.5 ORY92199.1 - 0.064 13.5 3.2 0.092 13.0 0.1 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4381 PF14316.6 ORY92199.1 - 0.066 13.5 0.1 0.066 13.5 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) FixQ PF05545.11 ORY92199.1 - 0.2 11.6 0.4 0.79 9.7 0.2 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ EphA2_TM PF14575.6 ORY92199.1 - 0.26 12.2 0.6 1.9 9.4 0.0 2.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 ORY92199.1 - 0.81 10.1 3.7 3.7 8.0 3.7 2.0 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Cyclin_N PF00134.23 ORY92200.1 - 2.4e-07 30.5 0.1 3e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY92200.1 - 9e-07 29.4 0.1 1.2e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin VWA_CoxE PF05762.14 ORY92200.1 - 0.00033 20.1 0.3 0.00047 19.6 0.3 1.1 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein SET PF00856.28 ORY92201.1 - 6.9e-13 49.3 0.2 1.1e-12 48.7 0.2 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY92201.1 - 1.8e-06 27.9 10.4 1.8e-06 27.9 10.4 2.1 2 0 0 2 2 2 1 MYND finger CpXC PF14353.6 ORY92201.1 - 0.95 9.5 5.5 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 CpXC protein PI3Ka PF00613.20 ORY92203.1 - 3.9e-59 199.2 0.4 7.4e-59 198.3 0.4 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 ORY92203.1 - 2.5e-52 178.2 0.7 2.4e-34 119.3 0.0 2.6 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 ORY92203.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) NMO PF03060.15 ORY92204.1 - 8.5e-60 202.9 0.2 7.5e-59 199.8 0.2 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY92204.1 - 2.7e-09 36.5 0.8 0.00072 18.7 0.4 2.3 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 ORY92204.1 - 0.014 14.6 0.1 0.023 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 ORY92204.1 - 0.025 13.7 1.7 0.034 13.3 0.2 1.9 3 0 0 3 3 3 0 Conserved region in glutamate synthase FMN_dh PF01070.18 ORY92204.1 - 0.052 12.6 0.3 0.086 11.8 0.3 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1902 PF08972.11 ORY92204.1 - 0.13 12.3 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Mito_carr PF00153.27 ORY92205.1 - 2.3e-32 110.8 2.1 7e-16 57.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP-bdg_M PF16360.5 ORY92206.1 - 0.011 16.3 1.6 0.019 15.6 1.6 1.4 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region PRKG1_interact PF15898.5 ORY92206.1 - 0.028 15.3 0.6 0.051 14.5 0.6 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF1192 PF06698.11 ORY92206.1 - 0.029 14.4 0.2 0.061 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF2205 PF10224.9 ORY92206.1 - 0.052 13.5 1.8 0.095 12.7 1.8 1.4 1 0 0 1 1 1 0 Short coiled-coil protein TMF_TATA_bd PF12325.8 ORY92206.1 - 0.1 12.8 2.4 5.5 7.3 2.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 ORY92206.1 - 0.15 12.3 2.4 0.31 11.3 1.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Smg8_Smg9 PF10220.9 ORY92207.1 - 1.8e-79 268.1 16.8 6.9e-36 124.0 0.1 3.0 2 1 1 3 3 3 3 Smg8_Smg9 FOLN PF09289.10 ORY92207.1 - 1.2 9.3 6.3 1.8 8.8 3.9 2.5 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain Smg8_Smg9 PF10220.9 ORY92208.1 - 0.0078 14.6 0.2 0.0098 14.3 0.2 1.0 1 0 0 1 1 1 1 Smg8_Smg9 PHD PF00628.29 ORY92209.1 - 5.9e-06 26.1 8.1 5.9e-06 26.1 8.1 2.7 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 ORY92209.1 - 0.01 15.7 1.5 0.01 15.7 1.5 3.5 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 ORY92209.1 - 0.43 10.7 13.1 0.35 11.0 3.8 3.4 2 1 0 2 2 2 0 KIAA1045 RING finger Epimerase PF01370.21 ORY92210.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY92210.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GLTSCR1 PF15249.6 ORY92211.1 - 1.4e-22 80.1 0.6 1.4e-22 80.1 0.6 2.8 3 1 0 3 3 3 1 Conserved region of unknown function on GLTSCR protein Neur_chan_memb PF02932.16 ORY92211.1 - 9.2 6.2 15.5 0.99 9.4 4.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CotH PF08757.11 ORY92212.1 - 1.5e-39 136.5 3.8 2e-39 136.0 3.8 1.1 1 0 0 1 1 1 1 CotH kinase protein CotH PF08757.11 ORY92213.1 - 2.1e-35 122.8 3.8 2.9e-35 122.4 3.8 1.1 1 0 0 1 1 1 1 CotH kinase protein BCAS2 PF05700.11 ORY92214.1 - 2.7e-50 170.9 14.3 3e-50 170.8 14.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CHGN PF05679.16 ORY92214.1 - 0.016 14.0 0.5 0.018 13.9 0.5 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase YejG PF13989.6 ORY92214.1 - 0.045 14.2 0.3 0.11 13.0 0.1 1.7 1 1 1 2 2 2 0 YejG-like protein HAUS-augmin3 PF14932.6 ORY92214.1 - 0.071 12.7 13.5 0.91 9.1 7.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Hydantoinase_A PF01968.18 ORY92214.1 - 0.23 10.7 0.1 0.32 10.2 0.1 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Cnn_1N PF07989.11 ORY92214.1 - 0.47 10.6 8.0 0.19 11.9 3.9 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Lipase_GDSL PF00657.22 ORY92216.1 - 5.1e-10 39.7 0.1 7.1e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RNA_pol_3_Rpc31 PF11705.8 ORY92217.1 - 0.78 9.9 17.8 0.63 10.3 15.2 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_2 PF13639.6 ORY92218.1 - 3.1e-12 46.6 14.4 4.9e-12 46.0 14.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY92218.1 - 3.9e-09 36.1 6.5 7.8e-09 35.1 6.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY92218.1 - 1.3e-06 28.1 13.5 2.3e-06 27.3 13.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY92218.1 - 8.2e-06 26.0 9.4 2e-05 24.8 9.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY92218.1 - 0.0003 20.7 11.4 0.00049 20.0 11.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY92218.1 - 0.00039 20.2 10.6 0.00058 19.7 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY92218.1 - 0.00069 19.4 12.6 0.0012 18.7 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY92218.1 - 0.0011 19.0 5.5 0.0011 19.0 5.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY92218.1 - 0.0041 17.1 4.4 0.0077 16.3 4.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY92218.1 - 0.0046 16.5 8.8 0.0081 15.8 8.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY92218.1 - 0.11 12.4 12.1 0.2 11.6 12.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RRM_1 PF00076.22 ORY92220.1 - 1.2e-12 47.4 0.0 3.7e-05 23.5 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY92220.1 - 0.0063 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif IBR PF01485.21 ORY92221.1 - 7.3e-12 45.3 12.3 6.6e-08 32.7 2.9 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-WRNIP1_ubi PF18279.1 ORY92221.1 - 0.25 12.1 0.1 0.25 12.1 0.1 3.7 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain TPR_2 PF07719.17 ORY92222.1 - 1.2e-10 40.6 14.8 0.00016 21.5 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY92222.1 - 8.6e-09 34.9 2.4 0.0022 18.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY92222.1 - 1.4e-06 27.9 9.4 0.095 12.6 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY92222.1 - 2.4e-06 27.9 4.7 0.32 11.5 0.5 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY92222.1 - 3.5e-06 27.5 8.2 0.11 13.1 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY92222.1 - 2.2e-05 24.2 2.9 0.21 11.7 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY92222.1 - 2.3e-05 24.5 1.7 11 6.7 0.1 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY92222.1 - 2.7e-05 24.6 21.7 0.0026 18.4 2.0 6.6 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY92222.1 - 0.0013 18.4 1.8 0.19 11.5 0.0 4.5 7 0 0 7 7 7 1 TPR repeat DUF4824 PF16106.5 ORY92222.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) TPR_12 PF13424.6 ORY92222.1 - 0.071 13.4 10.0 0.65 10.3 0.4 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY92222.1 - 0.5 10.6 11.6 0.86 9.9 0.1 4.8 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY92222.1 - 4 8.4 12.6 5.2 8.0 1.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY92222.1 - 5.3 7.3 17.2 17 5.6 0.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 ORY92223.1 - 1.5e-13 50.6 0.0 3.5e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ORY92223.1 - 3e-12 46.7 0.0 2e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 ORY92223.1 - 1.8e-07 31.7 0.0 4.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY92223.1 - 0.021 15.2 0.6 0.021 15.2 0.6 2.6 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 ORY92223.1 - 0.049 13.6 0.2 0.16 11.9 0.2 2.0 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF3425 PF11905.8 ORY92224.1 - 2.1e-14 53.6 1.5 4.3e-14 52.6 0.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORY92224.1 - 1.6e-08 34.5 6.1 4.3e-08 33.1 6.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor CASP_C PF08172.12 ORY92224.1 - 0.00089 18.7 0.6 0.0023 17.3 0.6 1.6 1 0 0 1 1 1 1 CASP C terminal SHE3 PF17078.5 ORY92224.1 - 0.0065 16.2 0.7 0.012 15.4 0.7 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 KASH_CCD PF14662.6 ORY92224.1 - 0.068 13.0 3.1 0.14 12.0 3.1 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 ORY92224.1 - 0.29 11.8 2.7 0.23 12.1 0.5 1.9 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_Maf PF03131.17 ORY92224.1 - 8.8 6.9 15.6 0.81 10.2 8.2 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Cu-oxidase PF00394.22 ORY92225.1 - 5.9e-31 107.7 0.0 3.5e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY92225.1 - 9.9e-26 90.1 6.6 2.7e-18 66.1 0.2 3.3 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY92225.1 - 1.1e-23 83.4 5.8 1.3e-10 41.2 0.5 4.7 4 1 0 4 4 4 2 Multicopper oxidase ubiquitin PF00240.23 ORY92226.1 - 8.2e-23 80.0 0.0 8.8e-23 79.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY92226.1 - 4.2e-12 45.7 0.0 4.6e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 ORY92226.1 - 0.00034 20.5 0.0 0.00037 20.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 ORY92226.1 - 0.0005 20.5 0.0 0.0012 19.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain FAD_binding_2 PF00890.24 ORY92227.1 - 7.4e-125 417.3 4.8 9.4e-125 417.0 4.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ORY92227.1 - 6.7e-44 149.0 1.3 1e-43 148.4 1.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 ORY92227.1 - 4e-06 26.2 1.9 0.014 14.5 2.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ORY92227.1 - 1.1e-05 24.9 0.6 0.0054 16.0 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 ORY92227.1 - 1.2e-05 24.6 0.5 0.00097 18.3 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY92227.1 - 5.5e-05 22.5 2.7 0.00082 18.7 1.3 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY92227.1 - 0.002 17.8 1.6 0.0095 15.5 1.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY92227.1 - 0.0074 15.6 0.2 0.014 14.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY92227.1 - 0.015 14.0 1.2 0.2 10.3 0.5 2.8 4 0 0 4 4 4 0 HI0933-like protein NAD_binding_8 PF13450.6 ORY92227.1 - 0.94 9.8 4.4 0.6 10.4 1.6 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY92227.1 - 1.3 8.2 3.1 1.5 8.0 0.5 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-MIZ PF02891.20 ORY92228.1 - 0.21 11.3 1.3 0.27 11.0 0.2 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF1192 PF06698.11 ORY92229.1 - 0.075 13.1 1.1 2.2 8.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Fzo_mitofusin PF04799.13 ORY92229.1 - 0.13 11.8 3.1 0.27 10.8 3.1 1.4 1 0 0 1 1 1 0 fzo-like conserved region HAMP PF00672.25 ORY92230.1 - 5.9e-162 526.1 70.9 2.4e-08 34.2 0.1 22.5 21 1 0 21 21 21 20 HAMP domain HATPase_c PF02518.26 ORY92230.1 - 7.3e-31 107.0 0.4 1.3e-29 103.0 0.2 3.6 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY92230.1 - 1e-28 99.7 3.4 3.3e-25 88.4 0.2 4.8 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 ORY92230.1 - 5e-17 61.7 4.9 1.7e-16 60.0 0.5 4.7 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.17 ORY92230.1 - 1.2e-12 47.6 1.7 97 3.1 0.0 15.6 17 0 0 17 17 17 0 Helix-turn-helix domain, rpiR family Baculo_PEP_C PF04513.12 ORY92230.1 - 9.1e-12 45.2 137.7 0.22 11.6 0.8 21.9 9 3 9 22 22 22 12 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1843 PF08898.10 ORY92230.1 - 6.6e-08 32.9 21.3 29 5.3 0.0 15.3 19 0 0 19 19 19 0 Domain of unknown function (DUF1843) ImcF-related_N PF14331.6 ORY92230.1 - 1.2e-05 24.8 9.7 20 4.5 0.0 10.9 7 3 6 14 14 14 0 ImcF-related N-terminal domain DUF4279 PF14106.6 ORY92230.1 - 2.2e-05 24.6 0.1 53 4.0 0.0 10.6 17 0 0 17 17 14 0 Domain of unknown function (DUF4279) SpoIIID PF12116.8 ORY92230.1 - 0.00059 19.9 32.7 8.7 6.5 0.0 15.0 18 0 0 18 18 18 1 Stage III sporulation protein D WXG100 PF06013.12 ORY92230.1 - 0.0044 17.2 60.0 3.4 8.0 0.0 17.8 19 3 2 21 21 21 1 Proteins of 100 residues with WXG PhoR PF11808.8 ORY92230.1 - 0.0076 16.6 0.0 60 4.1 0.0 5.9 7 0 0 7 7 7 0 Phosphate regulon sensor protein PhoR VHS PF00790.19 ORY92230.1 - 0.0095 15.8 0.2 0.049 13.5 0.2 2.3 1 0 0 1 1 1 1 VHS domain MVP_shoulder PF11978.8 ORY92230.1 - 0.14 12.1 7.4 1.1e+02 2.8 0.0 7.8 9 1 1 10 10 9 0 Shoulder domain DUF1759 PF03564.15 ORY92230.1 - 0.22 11.5 39.5 36 4.3 0.0 14.9 19 0 0 19 19 19 0 Protein of unknown function (DUF1759) AAA_24 PF13479.6 ORY92230.1 - 0.61 9.8 5.2 18 5.0 0.0 5.1 4 1 1 5 5 5 0 AAA domain Homeodomain PF00046.29 ORY92231.1 - 3.3e-17 62.1 6.7 6.7e-17 61.1 6.7 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 ORY92231.1 - 0.011 15.1 0.1 0.039 13.4 0.1 2.0 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PAP1 PF08601.10 ORY92231.1 - 0.11 12.2 15.9 0.17 11.6 15.9 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 Homeobox_KN PF05920.11 ORY92231.1 - 0.14 12.1 2.2 0.27 11.2 0.6 2.3 2 0 0 2 2 2 0 Homeobox KN domain MscS_TM PF12794.7 ORY92231.1 - 0.38 9.6 0.8 0.53 9.1 0.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 GREB1 PF15782.5 ORY92231.1 - 0.77 6.8 11.7 0.9 6.6 11.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PRC2_HTH_1 PF18118.1 ORY92231.1 - 2.4 9.0 10.5 0.68 10.8 1.8 2.1 1 1 1 2 2 2 0 Polycomb repressive complex 2 tri-helical domain GET2 PF08690.10 ORY92231.1 - 3.8 7.1 11.6 5.1 6.7 11.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SR-25 PF10500.9 ORY92231.1 - 5.8 6.4 20.0 4.3 6.9 10.1 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1682 PF07946.14 ORY92232.1 - 5.1e-81 272.4 4.2 6e-81 272.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) U79_P34 PF03064.16 ORY92232.1 - 0.13 11.6 8.4 0.18 11.1 8.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 THOC7 PF05615.13 ORY92233.1 - 2.3e-20 73.2 2.6 2.3e-20 73.2 2.6 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 Glyco_transf_29 PF00777.18 ORY92233.1 - 0.0038 16.7 0.1 0.0071 15.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) ING PF12998.7 ORY92233.1 - 0.56 10.8 12.5 4.9 7.8 3.6 2.8 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Tho2 PF11262.8 ORY92233.1 - 3 7.0 11.9 0.63 9.2 7.4 2.0 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Pyridoxal_deC PF00282.19 ORY92234.1 - 1.1e-66 225.1 0.0 1.6e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY92234.1 - 0.00088 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V AIM24 PF01987.17 ORY92235.1 - 2.9e-38 131.7 0.0 4.2e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Alpha_GJ PF03229.13 ORY92236.1 - 0.071 13.7 4.3 0.099 13.2 2.5 2.0 1 1 1 2 2 2 0 Alphavirus glycoprotein J HLH PF00010.26 ORY92237.1 - 1.2e-18 66.7 1.1 1.2e-18 66.7 1.1 2.7 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain McrBC PF10117.9 ORY92237.1 - 0.0034 16.6 0.8 0.0034 16.6 0.8 1.5 2 0 0 2 2 2 1 McrBC 5-methylcytosine restriction system component DFF40 PF09230.10 ORY92237.1 - 0.0071 16.0 1.8 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 DNA fragmentation factor 40 kDa Itfg2 PF15907.5 ORY92237.1 - 0.023 13.8 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 Baculo_helicase PF04735.12 ORY92237.1 - 0.076 10.5 0.1 0.095 10.2 0.1 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase Spc7_N PF15402.6 ORY92237.1 - 0.18 10.0 3.9 0.21 9.8 3.9 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SOG2 PF10428.9 ORY92238.1 - 2.5 7.2 6.3 2.5 7.2 6.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 ORY92238.1 - 3.3 6.3 8.7 4.2 5.9 8.7 1.2 1 0 0 1 1 1 0 Hamartin protein RskA PF10099.9 ORY92238.1 - 3.9 7.7 29.4 0.43 10.8 14.2 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Cas1_AcylT PF07779.12 ORY92239.1 - 2e-133 445.8 22.2 2.7e-133 445.3 22.2 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 ORY92239.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Adaptin_N PF01602.20 ORY92240.1 - 2.4e-106 356.4 4.4 3.6e-106 355.8 4.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 ORY92240.1 - 2.6e-61 205.2 0.1 6.5e-61 204.0 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 ORY92240.1 - 6.4e-58 194.6 1.3 1.8e-57 193.2 1.3 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 ORY92240.1 - 4.1e-10 39.9 0.3 0.021 15.2 0.0 5.2 2 2 4 6 6 6 4 HEAT repeats Cnd1 PF12717.7 ORY92240.1 - 2e-07 31.2 11.6 1.4e-06 28.5 0.0 3.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 ORY92240.1 - 1.6e-05 24.5 4.9 0.0044 16.5 1.0 3.0 3 0 0 3 3 3 2 Family of unknown function (DUF5578) HEAT PF02985.22 ORY92240.1 - 4e-05 23.5 0.9 0.15 12.4 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 ORY92240.1 - 0.001 19.2 0.0 0.0049 17.0 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF5071 PF16804.5 ORY92240.1 - 0.0037 17.5 1.1 0.18 12.1 0.0 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF5071) HEAT_EZ PF13513.6 ORY92240.1 - 0.0055 17.2 1.2 2.2 8.9 0.0 4.4 5 0 0 5 5 4 1 HEAT-like repeat DUF2326 PF10088.9 ORY92240.1 - 0.015 15.1 0.3 0.044 13.5 0.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) DNA_pol3_a_NII PF11490.8 ORY92240.1 - 0.054 13.4 2.3 0.32 10.9 1.6 2.7 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Beta_elim_lyase PF01212.21 ORY92241.1 - 6.8e-73 245.5 0.0 1e-72 244.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORY92241.1 - 1.5e-09 37.5 0.0 2.3e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY92241.1 - 0.0017 17.7 0.8 0.011 15.1 0.1 2.4 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family AP_endonuc_2 PF01261.24 ORY92241.1 - 0.0042 16.5 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel Pyridoxal_deC PF00282.19 ORY92241.1 - 0.0068 15.2 0.2 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain MotCF PF09158.10 ORY92241.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal Methyltransf_32 PF13679.6 ORY92242.1 - 3.2e-25 89.0 0.4 5.3e-25 88.3 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY92242.1 - 0.00051 19.9 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY92242.1 - 0.0086 15.6 0.3 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY92242.1 - 0.056 14.2 0.1 0.21 12.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 ORY92242.1 - 0.057 13.5 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 ORY92242.1 - 0.11 13.1 0.0 0.38 11.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S8_N PF16361.5 ORY92243.1 - 0.0038 17.7 0.6 0.016 15.7 0.4 1.9 2 0 0 2 2 2 1 N-terminal of Subtilase family Ras PF00071.22 ORY92244.1 - 5.4e-61 204.9 0.1 7.4e-61 204.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY92244.1 - 7.4e-35 119.8 0.1 1.4e-34 118.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY92244.1 - 2.4e-12 46.7 0.0 3.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY92244.1 - 5.1e-06 26.5 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY92244.1 - 0.0023 17.8 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY92244.1 - 0.0025 17.4 0.3 0.033 13.7 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY92244.1 - 0.0043 16.5 0.0 0.0084 15.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORY92244.1 - 0.007 16.6 0.1 0.06 13.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain DLIC PF05783.11 ORY92244.1 - 0.0098 14.8 0.1 0.087 11.6 0.1 1.9 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 ORY92244.1 - 0.02 15.3 0.1 0.032 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 ORY92244.1 - 0.024 14.0 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 ORY92244.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 ORY92244.1 - 0.049 13.4 0.0 0.13 11.9 0.0 1.6 1 1 0 2 2 2 0 AAA domain TniB PF05621.11 ORY92244.1 - 0.08 12.3 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 ORY92244.1 - 0.087 12.4 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 ORY92244.1 - 0.14 11.7 0.1 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RE_EcoO109I PF14511.6 ORY92245.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I SH3_1 PF00018.28 ORY92247.1 - 2.1e-11 43.3 0.8 3.5e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ORY92247.1 - 1e-09 37.9 0.0 2.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY92247.1 - 5.8e-07 29.3 0.0 9.7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 ORY92247.1 - 0.01 15.6 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain E3_UFM1_ligase PF09743.9 ORY92248.1 - 7.6e-26 91.3 0.0 9.5e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Sec8_exocyst PF04048.14 ORY92249.1 - 1.4e-25 89.8 2.0 2.7e-14 53.3 0.1 2.9 1 1 1 2 2 2 2 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 ORY92249.1 - 1.8e-05 24.7 0.0 4.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54 PF07928.12 ORY92249.1 - 0.52 10.8 4.0 2 8.8 0.2 3.2 3 0 0 3 3 3 0 Vps54-like protein IZUMO PF15005.6 ORY92249.1 - 0.7 10.4 3.9 4.2 7.9 1.4 3.2 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated UPF0113_N PF17833.1 ORY92250.1 - 3.5e-29 101.2 0.0 5.4e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 ORY92250.1 - 2.2e-25 88.7 0.0 3.6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain DUF2034 PF10356.9 ORY92251.1 - 9.5e-19 67.5 0.0 4.1e-11 42.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 ORY92251.1 - 0.0024 17.9 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease PNP_UDP_1 PF01048.20 ORY92252.1 - 3.7e-28 98.3 0.0 4.6e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Gp_dh_C PF02800.20 ORY92253.1 - 4.9e-70 234.2 0.0 7.8e-70 233.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORY92253.1 - 5.8e-38 129.3 0.2 1e-37 128.5 0.2 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ORY92253.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SPRY PF00622.28 ORY92254.1 - 1.8e-21 76.4 0.1 3.4e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 SPRY domain BCS1_N PF08740.11 ORY92255.1 - 4.8e-52 176.7 0.1 6.9e-52 176.2 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORY92255.1 - 4.6e-20 72.4 0.0 8.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORY92255.1 - 0.00056 19.2 0.0 0.00098 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 ORY92255.1 - 0.00089 19.7 0.0 0.0044 17.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY92255.1 - 0.0023 18.5 0.0 0.0053 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY92255.1 - 0.0043 17.2 0.0 0.025 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY92255.1 - 0.0044 16.7 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 ORY92255.1 - 0.0096 16.3 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_21 PF13304.6 ORY92255.1 - 0.011 15.5 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 ORY92255.1 - 0.014 15.4 0.0 0.038 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY92255.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 ORY92255.1 - 0.016 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORY92255.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY92255.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 ORY92255.1 - 0.064 13.2 0.0 0.68 9.8 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 ORY92255.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY92255.1 - 0.099 12.7 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 ORY92255.1 - 0.14 12.6 0.0 0.7 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY92255.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 KaiC zf-C2H2 PF00096.26 ORY92256.1 - 5.8e-11 42.2 12.2 8.1e-06 26.0 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY92256.1 - 6.8e-07 29.6 10.8 0.0012 19.5 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY92256.1 - 7.2e-07 29.4 16.3 2.1e-05 24.7 1.7 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY92256.1 - 0.0033 17.7 1.6 0.14 12.4 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY92256.1 - 0.0046 17.3 1.8 0.16 12.4 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY92256.1 - 0.056 13.5 2.1 1.4 9.0 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY92256.1 - 0.058 13.2 6.6 0.53 10.1 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 ORY92256.1 - 1.7 8.6 11.2 0.34 10.8 1.7 3.0 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Nup96 PF12110.8 ORY92257.1 - 1.7e-12 47.1 0.6 2.4e-12 46.6 0.1 1.5 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 ORY92258.1 - 5.7e-50 169.3 0.0 8.3e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Peptidase_M24 PF00557.24 ORY92259.1 - 1.2e-42 146.0 0.0 2e-42 145.3 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_60s PF00428.19 ORY92259.1 - 0.59 10.8 6.4 3.4 8.3 5.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nse4_C PF08743.10 ORY92260.1 - 8e-26 90.1 0.0 8e-26 90.1 0.0 2.6 2 1 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 ORY92260.1 - 1.4e-09 37.9 0.6 1.4e-09 37.9 0.6 2.9 3 0 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE Merozoite_SPAM PF07133.11 ORY92260.1 - 0.0032 17.5 20.5 0.0032 17.5 20.5 1.7 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) GET2 PF08690.10 ORY92260.1 - 2 8.0 9.1 3.6 7.2 9.1 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 GYF PF02213.16 ORY92261.1 - 1.9e-20 72.3 0.4 4.3e-20 71.1 0.4 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 ORY92261.1 - 2.2e-05 24.2 0.2 0.00052 19.8 0.1 2.9 2 0 0 2 2 2 1 GYF domain 2 EAP30 PF04157.16 ORY92262.1 - 3.9e-72 242.4 0.1 4.3e-72 242.2 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.12 ORY92262.1 - 0.0091 15.9 1.3 0.044 13.7 0.1 2.2 2 1 0 2 2 2 1 Bacteriophage Mu Gam like protein GAS PF13851.6 ORY92262.1 - 0.044 13.1 3.1 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Protoglobin PF11563.8 ORY92262.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protoglobin TFIIE_alpha PF02002.17 ORY92262.1 - 0.21 11.5 1.2 1.1 9.1 0.0 2.7 3 1 0 3 3 3 0 TFIIE alpha subunit Dor1 PF04124.12 ORY92263.1 - 1.4e-68 231.1 8.4 2.2e-68 230.5 8.4 1.3 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 ORY92263.1 - 0.00012 22.0 4.6 0.00062 19.6 1.3 2.9 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Protoglobin PF11563.8 ORY92263.1 - 0.0016 18.3 1.8 0.0058 16.5 1.8 1.9 1 0 0 1 1 1 1 Protoglobin Vps51 PF08700.11 ORY92263.1 - 0.002 18.2 0.0 0.0083 16.2 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 FhuF PF06276.12 ORY92263.1 - 0.18 12.2 2.8 2.6 8.4 0.1 3.4 3 1 0 3 3 3 0 Ferric iron reductase FhuF-like transporter Cytidylate_kin PF02224.18 ORY92264.1 - 9.3e-44 149.7 9.5 3.5e-43 147.8 9.5 1.7 1 1 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 ORY92264.1 - 0.0089 16.2 0.5 0.011 15.9 0.5 1.3 1 0 0 1 1 1 1 Cytidylate kinase-like family PQ-loop PF04193.14 ORY92265.1 - 1.2e-37 127.5 12.7 3.2e-19 68.5 0.5 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 ORY92265.1 - 0.00066 19.7 1.3 0.00066 19.7 1.3 2.5 3 1 0 3 3 3 1 Sugar efflux transporter for intercellular exchange NIF PF03031.18 ORY92266.1 - 3.6e-14 52.8 0.0 6.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Lipase_3 PF01764.25 ORY92267.1 - 1.5e-15 57.3 0.0 4.1e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Acetyltransf_10 PF13673.7 ORY92268.1 - 1.7e-13 50.6 0.0 2.1e-13 50.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY92268.1 - 4.4e-11 43.1 0.0 5.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY92268.1 - 1.5e-10 41.4 0.0 2.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY92268.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.6 ORY92268.1 - 0.001 19.7 0.0 0.0024 18.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY92268.1 - 0.0034 17.5 0.0 0.0076 16.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY92268.1 - 0.0034 18.0 0.0 0.0041 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY92268.1 - 0.042 14.0 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 ORY92268.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain FKBP_C PF00254.28 ORY92269.1 - 9.8e-30 102.7 0.0 1.1e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 ORY92270.1 - 4.3e-32 110.3 0.0 4.9e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dynamin_M PF01031.20 ORY92271.1 - 1.4e-104 349.3 0.0 3.2e-104 348.1 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORY92271.1 - 1.7e-53 181.1 0.0 3.4e-53 180.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY92271.1 - 1.4e-30 105.3 0.4 3e-30 104.2 0.4 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY92271.1 - 0.00016 21.8 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RhoGAP PF00620.27 ORY92273.1 - 1.2e-41 142.0 0.3 3e-41 140.8 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY92273.1 - 4.4e-13 49.2 39.5 1.6e-05 25.0 6.8 5.1 4 1 0 4 4 4 4 LIM domain SUIM_assoc PF16619.5 ORY92273.1 - 0.016 15.3 3.0 0.053 13.6 3.0 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Uds1 PF15456.6 ORY92273.1 - 3.4 7.8 8.1 17 5.6 0.2 3.7 3 0 0 3 3 3 0 Up-regulated During Septation DUF3325 PF11804.8 ORY92274.1 - 0.01 16.0 2.3 1.6 8.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) AAA PF00004.29 ORY92276.1 - 3.5e-07 30.7 0.0 6.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY92276.1 - 0.0012 18.8 0.0 0.01 15.8 0.0 2.3 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 ORY92276.1 - 0.0029 18.0 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY92276.1 - 0.047 14.2 0.0 0.15 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORY92276.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain WD40 PF00400.32 ORY92277.1 - 2e-37 126.5 19.7 7.1e-09 36.2 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92277.1 - 1.4e-17 63.7 0.7 0.00018 21.7 0.0 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY92277.1 - 4.6e-13 49.1 0.0 1.3e-06 28.0 0.0 2.9 2 1 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 ORY92277.1 - 7.5e-10 39.0 0.2 0.00016 21.6 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY92277.1 - 0.0002 20.4 3.8 0.1 11.6 0.0 3.9 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 ORY92277.1 - 0.0028 18.1 6.1 3.2 8.4 0.2 4.6 5 0 0 5 5 5 1 PQQ-like domain RAB3GAP2_N PF14655.6 ORY92277.1 - 0.0073 15.6 0.1 0.69 9.1 0.1 2.2 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 ORY92277.1 - 0.0074 15.0 2.5 0.75 8.4 1.1 3.4 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Pkinase PF00069.25 ORY92278.1 - 1.6e-26 93.3 0.0 2.5e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92278.1 - 1e-12 47.9 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY92278.1 - 5.1e-09 35.4 0.0 8.3e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY92278.1 - 0.001 19.1 2.0 0.0052 16.7 0.0 2.8 2 2 1 3 3 3 1 Phosphotransferase enzyme family DUF5529 PF17669.1 ORY92278.1 - 0.82 9.7 11.9 1.6 8.8 11.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5529) AreA_N PF07573.11 ORY92278.1 - 4.4 8.0 7.3 0.19 12.4 0.6 2.2 3 0 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus His_Phos_1 PF00300.22 ORY92279.1 - 3.1e-24 85.8 0.0 3.5e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acetyltransf_5 PF13444.6 ORY92279.1 - 0.094 13.4 0.1 0.16 12.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_2 PF13233.6 ORY92280.1 - 1.4e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ORY92280.1 - 6.9e-12 45.2 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) T4SS_TraI PF16932.5 ORY92280.1 - 0.0056 15.9 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system, conjugal DNA-protein transfer Complex1_LYR_1 PF13232.6 ORY92280.1 - 0.033 14.8 0.0 0.052 14.2 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like SMAP PF15477.6 ORY92281.1 - 1.5e-14 54.7 3.2 1.5e-14 54.7 3.2 3.2 2 1 0 2 2 2 1 Small acidic protein family DUF1631 PF07793.11 ORY92281.1 - 1.3 7.3 13.5 1.9 6.8 13.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) Mt_ATP-synt_B PF05405.14 ORY92282.1 - 4.5e-45 153.2 8.5 5.6e-45 152.9 8.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5623 PF18536.1 ORY92282.1 - 0.022 15.0 1.1 0.069 13.4 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5623) DUF5314 PF17241.2 ORY92282.1 - 0.1 12.3 3.6 4 7.1 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5314) DUF4709 PF15821.5 ORY92282.1 - 0.12 12.6 3.2 0.59 10.4 3.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) MPP6 PF10175.9 ORY92283.1 - 2.1e-17 63.8 11.3 6.1e-17 62.4 11.3 1.7 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Utp14 PF04615.13 ORY92283.1 - 2.4e-05 23.1 12.5 2.8e-05 22.9 12.5 1.0 1 0 0 1 1 1 1 Utp14 protein Presenilin PF01080.17 ORY92283.1 - 8.7 5.0 5.2 12 4.5 5.2 1.2 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 ORY92285.1 - 1.3e-52 178.9 26.1 1.3e-52 178.9 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY92285.1 - 8e-15 54.6 6.3 8e-15 54.6 6.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORY92285.1 - 2.7e-12 45.9 5.0 5.9e-12 44.8 5.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY92285.1 - 2e-06 26.5 2.2 2e-06 26.5 2.2 2.2 2 1 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 ORY92285.1 - 0.00039 18.9 1.7 0.00039 18.9 1.7 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family S10_plectin PF03501.15 ORY92285.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Plectin/S10 domain FA_desaturase PF00487.24 ORY92285.1 - 1.5 8.6 6.3 3 7.6 0.3 3.1 3 0 0 3 3 3 0 Fatty acid desaturase LapA_dom PF06305.11 ORY92285.1 - 8.7 6.3 8.0 1.2 9.0 2.2 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HLH PF00010.26 ORY92286.1 - 2.6e-12 46.5 1.0 5e-12 45.6 1.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4125 PF13526.6 ORY92286.1 - 0.062 12.9 0.4 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4125) FUSC PF04632.12 ORY92286.1 - 0.24 9.9 6.1 0.31 9.5 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_18 PF13238.6 ORY92287.1 - 0.038 14.6 0.9 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORY92287.1 - 0.1 12.3 0.4 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PPR_2 PF13041.6 ORY92288.1 - 6.6e-25 87.1 4.4 2.7e-08 33.9 0.0 6.4 5 1 1 6 6 6 5 PPR repeat family PPR_3 PF13812.6 ORY92288.1 - 1.1e-16 60.6 0.0 2.7e-07 30.6 0.0 5.3 4 2 1 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 ORY92288.1 - 1.3e-13 50.2 0.5 0.00037 20.5 0.1 6.5 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.7 ORY92288.1 - 1e-09 37.9 5.1 0.039 13.7 0.0 6.5 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 ORY92288.1 - 7.2e-08 32.1 0.0 7.4e-07 28.7 0.0 2.3 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 ORY92288.1 - 0.035 14.6 1.7 43 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RPM2 PF08579.11 ORY92288.1 - 0.18 12.2 0.4 54 4.2 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) DUF3759 PF12585.8 ORY92289.1 - 1.2e-20 73.3 3.0 3.6e-20 71.8 2.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.6 ORY92289.1 - 0.00013 22.6 0.1 0.0062 17.2 0.0 3.0 2 2 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF3603 PF12227.8 ORY92289.1 - 0.16 11.3 1.7 0.27 10.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Mit_ribos_Mrp51 PF11709.8 ORY92290.1 - 2.2e-15 57.2 7.0 1.4e-10 41.4 5.5 3.9 2 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit Nif11 PF07862.11 ORY92290.1 - 0.0028 17.9 0.6 0.0053 17.0 0.6 1.5 1 0 0 1 1 1 1 Nif11 domain Surp PF01805.20 ORY92290.1 - 0.13 12.3 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 Surp module RCC1 PF00415.18 ORY92291.1 - 3.5e-24 85.2 4.2 1.5e-08 35.1 0.0 3.6 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY92291.1 - 6.1e-18 64.1 7.3 1.8e-08 34.0 2.5 3.8 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.11 ORY92291.1 - 0.0084 16.2 0.0 6.6 7.3 0.0 2.7 2 0 0 2 2 2 2 Two component regulator propeller HMG_box PF00505.19 ORY92292.1 - 1.6e-14 54.1 0.8 4e-14 52.8 0.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY92292.1 - 1.8e-11 44.5 0.9 5.4e-11 42.9 0.9 1.8 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 ORY92292.1 - 1.4e-10 41.4 0.1 2.3e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY92292.1 - 1.8e-08 34.4 0.1 3.3e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 ORY92292.1 - 0.00098 19.1 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Protamine_like PF06382.11 ORY92292.1 - 0.00098 19.3 1.7 0.0019 18.4 1.7 1.5 1 0 0 1 1 1 1 Protamine and protamine like WYL_3 PF18488.1 ORY92292.1 - 0.038 14.3 0.6 0.081 13.3 0.6 1.6 1 0 0 1 1 1 0 WYL domain DUF4632 PF15451.6 ORY92292.1 - 2 8.5 4.1 1.7 8.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) NST1 PF13945.6 ORY92293.1 - 6.4e-49 166.7 38.7 6.4e-49 166.7 38.7 4.7 3 1 1 4 4 4 1 Salt tolerance down-regulator SOG2 PF10428.9 ORY92293.1 - 1.5 7.9 24.4 2.4 7.3 24.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Myb_DNA-bind_6 PF13921.6 ORY92295.1 - 1.4e-05 25.3 0.1 2.8e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_23 PF13384.6 ORY92295.1 - 2.8e-05 23.8 0.1 5.5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ORY92295.1 - 0.00091 19.3 0.3 0.0017 18.4 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ORY92295.1 - 0.035 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Myb_DNA-binding PF00249.31 ORY92295.1 - 0.047 13.9 2.1 0.066 13.4 0.9 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY92295.1 - 0.076 13.1 0.2 0.076 13.1 0.2 2.0 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Macoilin PF09726.9 ORY92295.1 - 0.37 9.3 6.4 0.58 8.7 6.4 1.2 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 ORY92295.1 - 0.88 7.3 6.6 1.2 6.8 6.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit EFTUD2 PF16004.5 ORY92295.1 - 1.4 9.5 8.0 8.6 7.0 8.0 2.1 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus PPR_2 PF13041.6 ORY92296.1 - 7.3e-63 208.6 11.7 1.7e-09 37.7 0.0 16.9 11 4 9 20 20 20 15 PPR repeat family PPR PF01535.20 ORY92296.1 - 6.9e-54 176.4 13.0 0.00035 20.6 0.0 18.0 21 0 0 21 21 20 10 PPR repeat PPR_3 PF13812.6 ORY92296.1 - 2.7e-37 126.7 3.3 5.4e-06 26.4 0.0 11.7 9 2 6 15 15 14 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY92296.1 - 8.2e-36 121.4 2.3 0.00015 21.4 0.0 14.5 16 0 0 16 16 16 8 PPR repeat PPR_long PF17177.4 ORY92296.1 - 2e-28 99.2 14.5 3.8e-06 26.4 0.2 7.4 3 2 3 6 6 6 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORY92296.1 - 1.2e-08 35.0 28.1 1.4 9.9 0.1 12.6 12 3 3 15 15 12 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY92296.1 - 2e-08 34.6 20.6 1.5 9.4 0.3 8.8 7 2 1 8 8 7 3 Tetratricopeptide repeat RPM2 PF08579.11 ORY92296.1 - 0.00071 20.0 0.0 3.6 8.0 0.0 4.7 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ANAPC3 PF12895.7 ORY92296.1 - 0.0049 17.1 7.0 0.23 11.7 0.5 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY92296.1 - 0.0054 16.7 11.7 13 6.1 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY92296.1 - 0.011 16.3 6.1 19 6.2 0.0 6.7 6 0 0 6 6 5 0 Tetratricopeptide repeat MRP-S27 PF10037.9 ORY92296.1 - 0.032 13.1 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Plk4_PB2 PF18409.1 ORY92296.1 - 0.082 13.6 0.1 0.3 11.8 0.1 2.0 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 Wzy_C_2 PF11846.8 ORY92296.1 - 0.22 11.4 6.7 14 5.5 0.8 5.1 5 1 0 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 ORY92296.1 - 1.3 9.0 10.2 23 5.0 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat ELYS PF13934.6 ORY92296.1 - 1.3 8.9 6.9 13 5.6 0.0 4.0 4 0 0 4 4 4 0 Nuclear pore complex assembly TPR_2 PF07719.17 ORY92296.1 - 1.8 8.9 13.6 54 4.3 0.1 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY92298.1 - 6.6e-26 88.3 23.2 4.8e-08 32.5 0.1 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORY92298.1 - 1e-23 82.1 24.4 3.8e-09 36.0 0.0 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY92298.1 - 4.8e-20 70.0 13.9 2.2e-06 27.4 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY92298.1 - 1.3e-15 57.4 19.5 1.7e-07 31.4 0.9 7.3 6 1 2 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY92298.1 - 1.1e-13 51.2 23.2 1e-11 44.8 0.4 5.8 5 2 1 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORY92298.1 - 1.5e-12 47.9 12.4 0.00028 21.5 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY92298.1 - 4.1e-12 45.8 4.0 0.71 10.8 0.0 7.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY92298.1 - 1e-09 37.7 19.8 2.1e-06 27.4 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY92298.1 - 3e-09 36.4 14.8 3.7e-06 26.5 0.0 6.4 5 1 1 6 6 6 2 TPR repeat TPR_15 PF13429.6 ORY92298.1 - 1e-08 34.7 6.6 0.12 11.6 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY92298.1 - 2.2e-08 34.5 7.3 0.058 13.9 0.1 6.0 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY92298.1 - 4.8e-08 32.8 13.4 0.0036 17.6 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY92298.1 - 7.3e-06 26.3 17.5 3.5 8.5 0.1 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY92298.1 - 1.2e-05 25.0 16.4 0.035 14.0 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY92298.1 - 0.00047 20.2 0.9 16 5.8 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY92298.1 - 0.0037 17.3 11.2 0.33 11.0 0.4 4.8 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 ORY92298.1 - 0.012 14.9 2.5 8.8 5.4 0.0 3.2 1 1 1 3 3 3 0 FAT domain Coatomer_E PF04733.14 ORY92298.1 - 0.013 14.9 0.0 13 5.1 0.0 3.6 3 1 1 4 4 4 0 Coatomer epsilon subunit PPR PF01535.20 ORY92298.1 - 0.047 14.0 0.3 11 6.5 0.0 4.1 5 0 0 5 5 4 0 PPR repeat Sel1 PF08238.12 ORY92298.1 - 0.065 13.9 0.6 0.97 10.2 0.1 3.2 2 0 0 2 2 2 0 Sel1 repeat TPR_MalT PF17874.1 ORY92298.1 - 0.095 12.0 1.6 2.6 7.3 0.0 3.4 2 1 1 4 4 4 0 MalT-like TPR region TPR_3 PF07720.12 ORY92298.1 - 1.1 9.3 16.6 0.46 10.5 1.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 ORY92299.1 - 5e-39 134.3 9.6 1.7e-38 132.6 9.7 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY92299.1 - 8e-17 61.7 0.0 1.5e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Dopey_N PF04118.14 ORY92300.1 - 2.8e-110 368.2 1.0 5e-109 364.1 0.2 2.7 2 1 0 2 2 2 1 Dopey, N-terminal CCDC53 PF10152.9 ORY92300.1 - 0.63 10.4 9.0 0.62 10.5 1.2 3.0 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex LMBR1 PF04791.16 ORY92301.1 - 2.4e-27 96.1 18.5 1.3e-22 80.4 1.8 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF3742 PF12553.8 ORY92301.1 - 0.017 15.3 4.8 0.061 13.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) DUF4131 PF13567.6 ORY92301.1 - 1.1 8.9 0.0 1.1 8.9 0.0 5.2 5 1 1 6 6 6 0 Domain of unknown function (DUF4131) HLH PF00010.26 ORY92302.1 - 4.6e-11 42.5 0.5 4.6e-11 42.5 0.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Presenilin PF01080.17 ORY92302.1 - 5.8 5.6 5.7 7.3 5.2 5.7 1.1 1 0 0 1 1 1 0 Presenilin PGA2 PF07543.12 ORY92302.1 - 7.9 6.5 10.1 1.9 8.4 6.6 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 O-FucT PF10250.9 ORY92303.1 - 8.2e-22 78.3 0.6 1.8e-14 54.2 0.1 2.0 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase SKA2 PF16740.5 ORY92303.1 - 0.0091 15.8 0.2 0.019 14.8 0.2 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Tau95_N PF17682.1 ORY92303.1 - 0.03 14.5 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Tau95 Triple barrel domain DUF645 PF04875.12 ORY92303.1 - 0.19 11.8 0.2 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF645 bZIP_2 PF07716.15 ORY92304.1 - 1.2e-12 47.7 15.9 1.2e-12 47.7 15.9 2.5 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY92304.1 - 1.4e-11 44.3 14.5 1.4e-11 44.3 14.5 2.1 3 0 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 ORY92304.1 - 4.7e-05 23.8 9.4 4.7e-05 23.8 9.4 3.8 4 1 1 5 5 5 1 bZIP Maf transcription factor TMCO5 PF14992.6 ORY92304.1 - 0.015 14.9 5.3 0.032 13.8 5.3 1.6 1 0 0 1 1 1 0 TMCO5 family CortBP2 PF09727.9 ORY92304.1 - 0.019 14.9 12.4 0.051 13.5 6.0 3.1 3 0 0 3 3 3 0 Cortactin-binding protein-2 HALZ PF02183.18 ORY92304.1 - 0.13 12.5 10.9 0.16 12.2 2.2 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper TSC22 PF01166.18 ORY92304.1 - 0.14 12.5 2.3 0.4 11.0 2.3 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 ORY92304.1 - 8.1 6.3 12.0 1.7 8.5 4.6 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF4200 PF13863.6 ORY92304.1 - 9.5 6.7 17.1 5.4 7.4 8.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) RNA_pol_3_Rpc31 PF11705.8 ORY92305.1 - 3.3 7.9 21.9 7.5 6.7 10.6 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Sec62 PF03839.16 ORY92305.1 - 7.1 6.1 5.6 0.79 9.2 0.7 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 SDA1 PF05285.12 ORY92305.1 - 8.2 5.7 19.6 1.5 8.1 1.7 2.4 2 0 0 2 2 2 0 SDA1 AAA_3 PF07726.11 ORY92307.1 - 0.0043 16.9 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_S10 PF00450.22 ORY92308.1 - 5.1e-122 408.3 0.6 6.3e-122 408.0 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PEX11 PF05648.14 ORY92309.1 - 5.3e-17 62.0 2.1 9.6e-15 54.6 0.4 2.3 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Cullin PF00888.22 ORY92310.1 - 4.1e-209 696.2 9.6 5.1e-209 695.9 9.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY92310.1 - 9e-27 92.9 4.6 1.6e-26 92.1 2.7 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF2252 PF10009.9 ORY92310.1 - 0.01 14.9 3.7 0.022 13.8 3.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Rrf2 PF02082.20 ORY92310.1 - 0.1 12.9 0.0 0.37 11.2 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulator Hormone_1 PF00103.20 ORY92310.1 - 0.38 10.5 8.2 0.48 10.1 0.3 3.6 3 0 0 3 3 3 0 Somatotropin hormone family Myb_DNA-binding PF00249.31 ORY92311.1 - 9.2e-14 51.4 0.2 2.1e-13 50.2 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2 PF00096.26 ORY92311.1 - 7.3e-13 48.2 17.2 0.00021 21.6 1.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type Myb_DNA-bind_6 PF13921.6 ORY92311.1 - 1.6e-11 44.3 0.2 1.6e-11 44.3 0.2 1.8 2 0 0 2 2 1 1 Myb-like DNA-binding domain zf-H2C2_2 PF13465.6 ORY92311.1 - 1.4e-09 38.0 17.4 9.7e-06 25.8 2.0 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY92311.1 - 1.4e-08 34.9 14.8 0.027 15.3 1.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY92311.1 - 2.8e-06 27.2 11.5 0.008 16.2 0.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger SLIDE PF09111.10 ORY92311.1 - 0.019 15.0 0.3 0.079 13.0 0.0 2.1 2 0 0 2 2 2 0 SLIDE zf-LYAR PF08790.11 ORY92311.1 - 0.039 13.9 2.9 3 7.8 0.0 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_aberr PF17017.5 ORY92311.1 - 0.052 13.7 0.2 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger DUF3474 PF11960.8 ORY92311.1 - 0.084 13.1 1.3 0.19 11.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Nnf1 PF03980.14 ORY92311.1 - 0.12 12.8 4.4 0.3 11.5 4.4 1.7 1 0 0 1 1 1 0 Nnf1 Rap1_C PF11626.8 ORY92311.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_8 PF15909.5 ORY92311.1 - 0.17 12.2 3.1 0.47 10.8 2.3 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY92311.1 - 0.19 12.0 5.1 3.7 8.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CHDCT2 PF08074.11 ORY92311.1 - 0.51 10.5 0.0 0.51 10.5 0.0 2.9 4 0 0 4 4 3 0 CHDCT2 (NUC038) domain zf-met PF12874.7 ORY92311.1 - 1.8 9.0 11.8 9.9 6.7 1.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 ORY92311.1 - 4.5 7.5 6.6 24 5.1 0.1 3.5 3 1 1 4 4 4 0 Zic proteins zinc finger domain Muted PF14942.6 ORY92311.1 - 6.4 7.1 10.6 0.2 12.0 4.2 1.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein NifQ PF04891.12 ORY92311.1 - 8 6.8 7.9 0.74 10.1 2.3 2.1 2 0 0 2 2 2 0 NifQ HLH PF00010.26 ORY92312.1 - 1.7e-14 53.5 1.0 4.7e-14 52.1 1.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CRA PF06589.11 ORY92312.1 - 0.079 13.1 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) HDV_ag PF01517.18 ORY92312.1 - 0.14 11.9 1.3 3.2 7.5 0.3 2.2 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen GATA PF00320.27 ORY92313.1 - 1.8e-29 101.0 19.0 3.2e-15 55.4 4.6 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY92313.1 - 1e-07 31.4 6.1 0.00099 18.6 0.4 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY92313.1 - 0.00011 22.3 1.6 0.32 11.1 0.2 2.7 2 0 0 2 2 2 2 Zinc ribbon domain ArfGap PF01412.18 ORY92313.1 - 0.0026 17.8 2.8 0.25 11.4 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 ORY92313.1 - 0.0032 17.6 12.3 0.069 13.3 0.6 2.6 3 0 0 3 3 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 ORY92313.1 - 0.0052 16.7 4.8 0.2 11.6 0.6 2.8 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Sec2p PF06428.11 ORY92313.1 - 0.13 12.2 1.9 0.22 11.5 1.9 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p eIF-5_eIF-2B PF01873.17 ORY92313.1 - 0.19 11.6 5.9 3 7.7 0.6 2.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.13 ORY92313.1 - 0.39 10.8 3.1 1.8 8.7 0.1 2.8 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 ORY92313.1 - 1.1 9.3 16.0 0.95 9.5 0.9 3.5 2 1 1 3 3 3 0 Double zinc ribbon zf-RRN7 PF11781.8 ORY92313.1 - 2.8 7.7 6.2 2.8 7.7 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-Sec23_Sec24 PF04810.15 ORY92313.1 - 4.2 7.5 8.1 5.1 7.2 1.4 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 ORY92313.1 - 4.6 6.8 11.5 6.6 6.3 0.2 4.2 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L5_C PF00673.21 ORY92314.1 - 7.4e-22 77.3 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY92314.1 - 9.6e-19 67.5 0.1 3.2e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 DUF3113 PF11310.8 ORY92315.1 - 0.082 12.9 0.4 0.43 10.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3113) MIF4G PF02854.19 ORY92316.1 - 1e-29 103.7 5.9 3.7e-29 101.9 1.4 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 ORY92316.1 - 1.9e-23 82.6 0.1 8.4e-23 80.5 0.0 2.2 2 0 0 2 2 2 1 MA3 domain CDV3 PF15359.6 ORY92316.1 - 1.7 9.2 10.1 4.1 7.9 10.1 1.7 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 MFS_1 PF07690.16 ORY92317.1 - 4.2e-36 124.6 32.4 4.8e-36 124.4 32.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 ORY92317.1 - 0.0014 17.0 1.8 0.0014 17.0 1.8 2.5 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_L13 PF00572.18 ORY92318.1 - 0.0079 16.5 0.1 2.2 8.5 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein L13 Ras PF00071.22 ORY92320.1 - 3.2e-11 43.1 0.3 3.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY92320.1 - 2.6e-09 37.3 0.8 3e-06 27.5 0.3 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY92320.1 - 0.0074 15.8 0.1 0.12 11.8 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY92320.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SOG2 PF10428.9 ORY92321.1 - 1.9e-35 123.0 6.3 2.1e-25 89.9 0.6 2.9 1 1 2 3 3 3 2 RAM signalling pathway protein PAXNEB PF05625.11 ORY92322.1 - 4e-96 322.4 0.0 5.1e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 ORY92322.1 - 9.1e-06 25.2 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KaiC DHDPS PF00701.22 ORY92323.1 - 1.7e-51 174.7 0.0 2.1e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FAD_binding_1 PF00667.20 ORY92324.1 - 5.6e-56 189.6 0.0 9.7e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY92324.1 - 7e-37 126.8 0.2 2e-36 125.4 0.2 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY92324.1 - 4e-19 69.3 0.0 1.4e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glyco_tran_WecB PF03808.13 ORY92324.1 - 0.083 12.8 0.0 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Flavodoxin_5 PF12724.7 ORY92324.1 - 0.12 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Oxidored-like PF09791.9 ORY92325.1 - 5.1e-21 74.1 3.6 5.1e-21 74.1 3.6 1.9 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DUF4515 PF14988.6 ORY92325.1 - 0.031 14.1 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF5522 PF17653.1 ORY92325.1 - 0.035 14.1 2.8 0.071 13.1 2.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Apolipoprotein PF01442.18 ORY92325.1 - 0.1 12.5 0.2 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SNF2_N PF00176.23 ORY92326.1 - 4e-68 229.7 0.0 7e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY92326.1 - 8.4e-18 64.7 0.0 1.3e-16 60.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY92326.1 - 1.4e-07 31.7 0.0 2.7e-06 27.5 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY92326.1 - 0.00085 18.6 2.1 0.0016 17.7 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 ORY92326.1 - 0.0058 16.4 0.0 0.27 11.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase STN PF07660.14 ORY92326.1 - 0.083 12.7 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Elf1 PF05129.13 ORY92327.1 - 6.5e-17 61.4 9.4 4e-14 52.4 9.4 2.4 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.7 ORY92327.1 - 0.0048 17.2 0.4 0.0066 16.8 0.4 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) HetR_C PF18460.1 ORY92328.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain DUF3352 PF11832.8 ORY92328.1 - 0.14 10.8 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) AAA_6 PF12774.7 ORY92328.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RRM_1 PF00076.22 ORY92329.1 - 1.5e-15 56.8 0.0 1.1e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 ORY92329.1 - 0.0058 16.7 1.0 0.015 15.4 1.0 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Ank_4 PF13637.6 ORY92330.1 - 7.7e-06 26.4 0.2 0.00045 20.7 0.0 3.3 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY92330.1 - 4.2e-05 23.6 3.5 7.3 7.5 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 ORY92330.1 - 0.00014 22.3 0.1 0.0016 19.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) FAM176 PF14851.6 ORY92330.1 - 0.31 10.7 3.0 0.71 9.5 3.0 1.5 1 0 0 1 1 1 0 FAM176 family SPT6_acidic PF14632.6 ORY92330.1 - 0.62 10.7 12.2 1.6 9.4 12.2 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 THUMP PF02926.17 ORY92331.1 - 6.3e-07 29.6 0.0 9.5e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 THUMP domain E7 PF00527.18 ORY92331.1 - 0.23 11.7 1.7 0.39 10.9 0.6 2.0 2 0 0 2 2 2 0 E7 protein, Early protein MOSP_N PF02707.16 ORY92332.1 - 0.052 13.3 0.3 0.094 12.5 0.3 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein N-terminal region HABP4_PAI-RBP1 PF04774.15 ORY92333.1 - 0.026 15.4 0.0 0.031 15.1 0.0 1.3 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family DUF3808 PF10300.9 ORY92334.1 - 2e-69 234.6 10.6 3.1e-69 234.0 10.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 ORY92334.1 - 0.021 14.9 3.4 3.5 8.0 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pilin_GH PF16734.5 ORY92334.1 - 0.023 15.0 0.2 0.053 13.8 0.2 1.6 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative U1snRNP70_N PF12220.8 ORY92335.1 - 5.9e-25 87.7 3.1 1.4e-24 86.5 3.1 1.7 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 ORY92335.1 - 7.6e-17 60.9 0.0 1.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FmiP_Thoc5 PF09766.9 ORY92336.1 - 1.8e-35 122.9 14.9 1.8e-35 122.9 14.9 1.4 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 WD40 PF00400.32 ORY92337.1 - 6.7e-37 124.9 12.7 2.8e-05 24.8 0.0 11.5 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 ORY92337.1 - 3.5e-26 91.6 0.0 6.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ORY92337.1 - 9.7e-19 67.5 0.0 0.017 15.4 0.0 9.7 4 3 4 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY92337.1 - 2.5e-09 36.6 4.0 0.051 12.5 0.0 6.0 4 3 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 ORY92337.1 - 0.002 17.8 0.4 2.4 7.7 0.0 3.0 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Nbas_N PF15492.6 ORY92337.1 - 0.0024 17.3 2.1 14 4.9 0.1 5.7 4 2 2 7 7 7 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 ORY92337.1 - 0.0053 16.7 0.3 13 5.9 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ORY92337.1 - 0.013 14.8 0.0 0.12 11.6 0.0 2.6 3 1 0 4 4 4 0 WD40-like domain DPPIV_N PF00930.21 ORY92337.1 - 0.042 12.6 0.0 0.22 10.2 0.0 2.2 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region ELYS-bb PF16687.5 ORY92337.1 - 0.068 11.8 0.0 0.3 9.7 0.0 2.0 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin DUF1513 PF07433.11 ORY92337.1 - 0.092 11.8 0.0 0.58 9.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) FYVE PF01363.21 ORY92338.1 - 0.05 13.7 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 FYVE zinc finger UCH PF00443.29 ORY92339.1 - 2.8e-38 131.9 0.1 3.8e-38 131.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY92339.1 - 1.2e-12 48.1 0.9 4.3e-12 46.2 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY92339.1 - 2e-12 47.3 1.7 4.1e-12 46.2 1.7 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M18 PF02127.15 ORY92340.1 - 9.8e-174 578.2 0.0 1.1e-173 578.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ORY92340.1 - 4e-08 32.6 0.6 3.8e-06 26.1 0.3 2.3 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase DRMBL PF07522.14 ORY92341.1 - 9.7e-33 112.7 0.7 2.2e-32 111.5 0.7 1.6 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 ORY92341.1 - 4.9e-08 32.7 0.1 2.5e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY92341.1 - 0.072 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Aminotran_1_2 PF00155.21 ORY92342.1 - 4e-39 134.8 0.0 6.1e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II ANAPC4_WD40 PF12894.7 ORY92343.1 - 3.4e-14 52.9 0.3 3.8e-05 23.9 0.0 4.9 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY92343.1 - 3.7e-10 40.2 9.2 0.0032 18.3 0.0 6.3 6 2 0 6 6 6 2 WD domain, G-beta repeat IKI3 PF04762.12 ORY92343.1 - 4e-09 35.1 5.0 2.2e-05 22.7 2.4 3.9 3 2 1 4 4 4 3 IKI3 family eIF2A PF08662.11 ORY92343.1 - 1.4e-06 28.3 0.3 0.94 9.3 0.1 4.1 2 2 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 ORY92343.1 - 0.0011 17.8 8.0 2.5 6.8 0.1 5.6 3 3 2 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 ORY92343.1 - 0.048 13.6 1.7 13 5.9 0.1 4.8 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat BCL_N PF04714.13 ORY92344.1 - 0.003 17.6 1.1 0.0064 16.5 1.1 1.5 1 0 0 1 1 1 1 BCL7, N-terminal conserver region TFIIA PF03153.13 ORY92344.1 - 0.0062 16.6 23.6 0.0075 16.3 23.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit KAR9 PF08580.10 ORY92344.1 - 7.9 4.9 20.2 9.1 4.7 20.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PARM PF17061.5 ORY92344.1 - 9 6.3 32.5 12 6.0 32.5 1.2 1 0 0 1 1 1 0 PARM EVI2A PF05399.11 ORY92344.1 - 10 5.7 24.2 1.1 8.7 3.5 2.1 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) JAB PF01398.21 ORY92345.1 - 1.9e-12 47.2 0.0 4.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.31 ORY92345.1 - 1.9e-11 43.9 0.0 6.5e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Prok-JAB PF14464.6 ORY92345.1 - 1.2e-06 28.3 0.1 2.9e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 ORY92345.1 - 0.0033 17.6 0.1 0.015 15.5 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain FSA_C PF10479.9 ORY92345.1 - 0.0096 14.1 2.8 0.013 13.6 2.8 1.3 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus UPF0172 PF03665.13 ORY92345.1 - 0.022 14.8 0.2 0.094 12.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) CDC27 PF09507.10 ORY92345.1 - 8 5.7 40.5 5.4 6.3 15.5 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PRP1_N PF06424.12 ORY92346.1 - 1.7e-51 174.5 6.1 4.6e-51 173.1 6.1 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 ORY92346.1 - 7.4e-32 107.3 31.1 0.0019 18.9 0.0 15.3 4 4 12 16 16 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 ORY92346.1 - 4.9e-24 84.6 12.1 1e-08 35.6 0.1 9.5 7 2 4 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY92346.1 - 1.8e-14 52.6 10.5 1.2 9.5 0.1 11.7 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY92346.1 - 3.4e-10 39.9 5.6 0.51 11.1 0.0 9.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY92346.1 - 1.1e-09 37.9 1.9 0.066 13.6 0.0 8.7 9 1 2 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY92346.1 - 1.6e-09 37.2 4.6 2.9 8.3 0.0 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY92346.1 - 3.4e-09 37.2 12.3 0.041 14.5 0.5 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY92346.1 - 2.9e-06 27.4 4.8 0.034 14.3 0.1 4.4 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 ORY92346.1 - 5.1e-06 26.3 3.7 0.079 12.7 0.7 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 ORY92346.1 - 4.1e-05 23.2 1.1 1.9 8.5 0.1 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 ORY92346.1 - 7.8e-05 22.8 0.8 0.076 13.0 0.0 4.2 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) NARP1 PF12569.8 ORY92346.1 - 0.00044 19.3 13.0 0.002 17.1 0.1 5.2 4 1 1 6 6 6 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 ORY92346.1 - 0.00051 20.3 13.5 0.77 10.1 0.3 8.0 6 3 2 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY92346.1 - 0.00065 19.3 0.9 13 5.5 0.0 6.4 7 1 1 8 8 8 0 TPR repeat Wzy_C_2 PF11846.8 ORY92346.1 - 0.0019 18.2 2.7 2 8.3 0.1 4.6 3 2 1 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 ORY92346.1 - 0.0033 16.7 3.8 0.0033 16.7 3.8 6.4 2 1 5 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.6 ORY92346.1 - 0.0068 15.9 8.1 0.58 9.5 0.6 3.9 3 2 1 4 4 4 2 Soluble NSF attachment protein, SNAP RasGAP_C PF03836.15 ORY92346.1 - 0.037 14.2 4.1 0.16 12.1 0.2 3.2 3 1 0 3 3 3 0 RasGAP C-terminus TPR_4 PF07721.14 ORY92346.1 - 0.1 13.3 5.3 13 6.8 0.0 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat SAPS PF04499.15 ORY92348.1 - 4.2e-44 151.1 0.0 1.3e-24 86.9 0.0 2.1 1 1 1 2 2 2 2 SIT4 phosphatase-associated protein DUF148 PF02520.17 ORY92349.1 - 0.12 12.5 0.1 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 TPR_11 PF13414.6 ORY92349.1 - 0.65 9.7 2.5 20 5.0 0.1 2.7 3 0 0 3 3 3 0 TPR repeat Abhydrolase_6 PF12697.7 ORY92350.1 - 4.9e-19 69.8 1.4 6.8e-19 69.3 0.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY92350.1 - 3.3e-16 59.7 0.2 8.6e-16 58.3 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 ORY92350.1 - 2.1e-13 50.3 0.0 3.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 ORY92350.1 - 2.9e-11 43.1 0.0 6.5e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ORY92350.1 - 0.00012 22.0 0.3 0.00033 20.6 0.3 1.7 1 1 0 1 1 1 1 Serine hydrolase PTPlike_phytase PF14566.6 ORY92350.1 - 0.00032 20.9 0.0 0.00061 19.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 ORY92350.1 - 0.003 17.2 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AXE1 PF05448.12 ORY92350.1 - 0.0041 15.8 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ORY92350.1 - 0.097 12.5 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase WD40 PF00400.32 ORY92352.1 - 8.5e-10 39.1 0.0 0.0012 19.6 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92352.1 - 4.6e-08 33.3 0.0 0.012 15.9 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PDZ_5 PF17817.1 ORY92353.1 - 0.019 15.2 0.4 0.035 14.4 0.4 1.4 1 0 0 1 1 1 0 PDZ domain AAA_6 PF12774.7 ORY92354.1 - 6.6e-133 442.7 0.2 3.7e-130 433.7 0.0 3.7 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 ORY92354.1 - 9.7e-124 414.0 12.9 9.7e-124 414.0 12.9 3.7 3 1 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 ORY92354.1 - 3.3e-120 401.8 8.8 3.3e-120 401.8 8.8 6.7 6 2 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 ORY92354.1 - 2.3e-75 252.5 0.2 2.3e-75 252.5 0.2 4.8 4 1 1 5 5 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY92354.1 - 3.4e-69 233.0 0.0 2.1e-68 230.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 ORY92354.1 - 8.6e-49 166.4 0.1 3.8e-48 164.3 0.1 2.2 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 ORY92354.1 - 1.4e-44 152.6 8.8 1.4e-44 152.6 8.8 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 ORY92354.1 - 9.7e-42 142.5 0.0 1.1e-34 119.5 0.0 5.2 6 0 0 6 6 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY92354.1 - 2e-37 128.5 0.0 7.4e-37 126.7 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 ORY92354.1 - 7.3e-32 110.0 0.0 1.2e-28 99.6 0.0 4.2 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 ORY92354.1 - 2.2e-30 105.5 0.0 3.8e-12 46.4 0.0 6.4 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 ORY92354.1 - 3.6e-18 65.9 0.0 2e-17 63.5 0.0 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 ORY92354.1 - 6e-16 59.0 0.4 0.0037 17.5 0.0 5.9 5 0 0 5 5 4 3 AAA domain AAA PF00004.29 ORY92354.1 - 2e-13 50.9 0.0 0.004 17.6 0.0 5.5 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY92354.1 - 2.9e-11 43.7 2.4 0.014 15.5 0.0 5.9 5 0 0 5 5 5 3 AAA domain AAA_16 PF13191.6 ORY92354.1 - 2.7e-09 37.6 0.0 0.72 10.2 0.0 6.4 5 0 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.6 ORY92354.1 - 4.7e-09 36.9 1.8 0.097 13.2 0.0 6.3 6 0 0 6 6 5 2 AAA domain T2SSE PF00437.20 ORY92354.1 - 3.8e-07 29.4 0.0 0.028 13.5 0.0 4.1 3 1 1 4 4 4 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 ORY92354.1 - 2.9e-06 26.8 0.5 0.4 10.0 0.0 3.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ORY92354.1 - 4.1e-06 26.4 0.1 0.32 10.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 ORY92354.1 - 6.4e-06 26.3 1.9 3.2e-05 24.1 0.0 3.2 3 0 0 3 3 2 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 ORY92354.1 - 9.4e-06 25.2 0.0 0.56 9.5 0.0 4.2 4 0 0 4 4 4 2 FtsK/SpoIIIE family ABC_tran PF00005.27 ORY92354.1 - 2e-05 25.1 0.0 1.3 9.6 0.0 4.7 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.6 ORY92354.1 - 3.4e-05 23.7 0.1 6.3 6.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 ORY92354.1 - 0.00016 22.0 0.7 0.3 11.4 0.0 4.5 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 ORY92354.1 - 0.00027 20.9 0.0 5.5 6.9 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain IstB_IS21 PF01695.17 ORY92354.1 - 0.00074 19.3 0.1 0.51 10.0 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ORY92354.1 - 0.0016 18.8 0.0 2.5 8.5 0.0 4.6 4 0 0 4 4 4 1 RNA helicase AAA_25 PF13481.6 ORY92354.1 - 0.0042 16.7 0.0 0.41 10.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 ORY92354.1 - 0.0054 16.5 4.3 56 3.4 0.0 6.0 7 0 0 7 7 6 0 AAA domain AAA_21 PF13304.6 ORY92354.1 - 0.053 13.3 0.1 13 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 ORY92354.1 - 0.2 11.5 6.2 54 3.6 0.1 5.0 5 0 0 5 5 4 0 NACHT domain SRP54 PF00448.22 ORY92354.1 - 0.66 9.6 2.9 57 3.3 0.0 4.1 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain T3SSipB PF16535.5 ORY92354.1 - 1.2 9.6 18.5 22 5.5 0.2 4.9 4 0 0 4 4 4 0 Type III cell invasion protein SipB SRPRB PF09439.10 ORY92354.1 - 1.5 8.2 11.4 28 4.1 7.1 4.0 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit PK PF00224.21 ORY92355.1 - 2.3e-155 516.7 0.2 2.8e-155 516.5 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORY92355.1 - 2.5e-38 130.9 0.0 6.1e-38 129.7 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORY92355.1 - 0.00077 18.7 0.1 0.0022 17.2 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Pet127 PF08634.10 ORY92356.1 - 0.039 13.4 1.2 0.08 12.4 1.2 1.5 1 1 0 1 1 1 0 Mitochondrial protein Pet127 DUF3000 PF11452.8 ORY92356.1 - 0.084 12.4 0.1 0.095 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Spc7 PF08317.11 ORY92357.1 - 0.0049 15.8 36.2 0.18 10.7 20.7 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Macoilin PF09726.9 ORY92357.1 - 2.7 6.4 38.6 5.2 5.5 38.6 1.4 1 1 0 1 1 1 0 Macoilin family CENP-F_leu_zip PF10473.9 ORY92357.1 - 4.8 7.2 32.9 3.5 7.7 3.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM76 PF16046.5 ORY92357.1 - 4.9 6.4 35.1 5.8 6.2 15.0 2.3 1 1 1 2 2 2 0 FAM76 protein DUF812 PF05667.11 ORY92357.1 - 7.1 5.4 38.0 1.6 7.5 13.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 ORY92357.1 - 7.5 6.6 14.8 0.17 11.9 3.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Abhydrolase_5 PF12695.7 ORY92358.1 - 0.0014 18.4 0.1 0.024 14.4 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY92358.1 - 0.0021 17.4 0.1 0.066 12.5 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY92358.1 - 0.022 14.4 0.6 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY92358.1 - 0.033 13.7 1.3 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2183 PF09949.9 ORY92358.1 - 0.048 14.0 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Peptidase_S15 PF02129.18 ORY92358.1 - 0.27 10.8 2.6 0.57 9.7 0.1 2.2 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_transf_20 PF00982.21 ORY92359.1 - 1.6e-156 521.7 0.0 2.1e-156 521.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY92359.1 - 6.4e-75 251.3 0.0 1e-74 250.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY92359.1 - 3.5e-06 26.9 0.0 0.01 15.6 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 ORY92359.1 - 0.089 12.3 0.1 1.4 8.4 0.3 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 Phosducin PF02114.16 ORY92360.1 - 2.4e-22 79.1 1.8 3e-22 78.9 1.4 1.3 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 ORY92360.1 - 1.9e-05 24.6 0.1 3.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Spc29 PF17082.5 ORY92360.1 - 0.0022 17.9 0.4 0.0031 17.4 0.4 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 Rhomboid PF01694.22 ORY92361.1 - 1.1e-26 93.6 9.2 1.7e-26 93.0 9.2 1.3 1 0 0 1 1 1 1 Rhomboid family DUF3384 PF11864.8 ORY92362.1 - 3.1e-64 217.7 2.4 1.4e-63 215.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 ORY92362.1 - 5.9e-50 169.4 0.0 1.2e-49 168.4 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 ORY92362.1 - 7.2e-48 163.5 2.6 7.2e-48 163.5 2.6 2.9 3 0 0 3 3 3 2 Tuberin Spt20 PF12090.8 ORY92362.1 - 0.92 9.1 14.7 2.5 7.7 14.7 1.6 1 0 0 1 1 1 0 Spt20 family ALMS_motif PF15309.6 ORY92362.1 - 1.4 9.4 10.1 2.8 8.4 10.1 1.5 1 0 0 1 1 1 0 ALMS motif UPF0524 PF15823.5 ORY92362.1 - 1.7 8.0 4.8 14 5.0 0.3 2.5 2 0 0 2 2 2 0 UPF0524 of C3orf70 DUF4834 PF16118.5 ORY92362.1 - 6.6 7.8 5.1 22 6.1 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-C2H2_4 PF13894.6 ORY92363.1 - 0.00014 22.4 3.1 0.019 15.8 0.2 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 ORY92363.1 - 0.00063 20.0 1.5 0.17 12.3 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY92363.1 - 0.01 16.1 2.3 0.048 14.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_12 PF18658.1 ORY92363.1 - 0.043 13.4 0.3 0.54 9.9 0.0 2.8 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-C2H2 PF00096.26 ORY92363.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 ORY92363.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 ORY92363.1 - 1.8 9.0 5.8 18 5.7 0.1 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Endonuclease_7 PF02945.15 ORY92363.1 - 2.7 8.0 5.9 0.44 10.5 0.8 2.2 2 0 0 2 2 2 0 Recombination endonuclease VII CF222 PF15661.5 ORY92365.1 - 0.00059 18.9 3.9 0.00067 18.7 3.9 1.0 1 0 0 1 1 1 1 C6orf222, uncharacterised family EPL1 PF10513.9 ORY92365.1 - 0.044 14.2 2.0 0.066 13.6 2.0 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Rad52_Rad22 PF04098.15 ORY92366.1 - 1.6e-51 174.2 0.0 1.8e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein EFG_IV PF03764.18 ORY92366.1 - 0.052 13.3 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Elongation factor G, domain IV DcuA_DcuB PF03605.14 ORY92367.1 - 0.045 12.6 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter SAM_1 PF00536.30 ORY92367.1 - 0.072 13.5 0.1 0.24 11.9 0.1 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1640 PF07798.11 ORY92367.1 - 0.14 12.2 4.1 1.9 8.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) KH_1 PF00013.29 ORY92368.1 - 9.2e-19 67.0 0.0 1.5e-05 24.7 0.0 5.8 6 0 0 6 6 6 3 KH domain tRNA-synt_2d PF01409.20 ORY92369.1 - 3.5e-87 291.9 0.0 4.7e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 ORY92369.1 - 1.2e-21 76.7 1.2 3.7e-21 75.2 0.2 2.4 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 ORY92369.1 - 5.6e-06 25.9 0.0 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 ORY92369.1 - 1.4e-05 24.4 0.6 0.0015 17.7 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 ORY92369.1 - 0.0028 17.6 5.5 0.0077 16.2 5.5 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 ORY92369.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) S10_plectin PF03501.15 ORY92369.1 - 0.083 13.0 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Plectin/S10 domain HTH_45 PF14947.6 ORY92369.1 - 0.1 12.6 0.5 4.6 7.3 0.2 2.6 2 1 0 2 2 2 0 Winged helix-turn-helix CENP-I PF07778.11 ORY92370.1 - 5e-48 164.1 3.6 1.9e-47 162.2 3.6 1.8 1 1 0 1 1 1 1 Mis6 Prenyltrans PF00432.21 ORY92371.1 - 7.2e-26 89.6 15.2 8.4e-09 35.0 0.0 5.7 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat EMP24_GP25L PF01105.24 ORY92372.1 - 1.1e-49 168.8 1.9 1.3e-49 168.6 1.9 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DinB PF05163.12 ORY92372.1 - 0.024 14.5 2.1 0.037 14.0 2.1 1.3 1 1 0 1 1 1 0 DinB family MCU PF04678.13 ORY92372.1 - 0.034 14.2 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Sec16 PF12932.7 ORY92372.1 - 0.058 14.0 0.0 0.091 13.4 0.0 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region CoaE PF01121.20 ORY92373.1 - 4.7e-63 212.1 0.0 6.2e-63 211.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 ORY92373.1 - 3.3e-06 27.7 0.0 1.5e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY92373.1 - 0.0012 19.1 0.0 0.0024 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORY92373.1 - 0.057 13.8 0.1 0.32 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 ORY92373.1 - 0.071 13.2 0.2 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 ORY92373.1 - 0.12 12.5 0.0 0.34 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 ORY92373.1 - 0.16 11.8 0.1 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase Vps5 PF09325.10 ORY92374.1 - 1e-72 244.5 12.2 1.5e-72 243.9 12.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORY92374.1 - 7.4e-28 96.8 0.9 2.9e-26 91.7 0.0 2.8 3 1 0 3 3 3 1 PX domain TFR_dimer PF04253.15 ORY92374.1 - 0.00081 19.5 2.7 0.0065 16.6 2.2 2.6 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain FUSC PF04632.12 ORY92374.1 - 0.061 11.9 1.2 0.09 11.3 1.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF848 PF05852.11 ORY92374.1 - 0.075 13.2 10.2 0.033 14.3 5.4 2.5 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SLATT_6 PF18169.1 ORY92374.1 - 0.3 10.7 2.3 0.58 9.7 2.3 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 BAR_3 PF16746.5 ORY92374.1 - 0.35 10.5 19.0 0.027 14.2 5.3 2.6 2 1 1 3 3 3 0 BAR domain of APPL family Terminase_4 PF05119.12 ORY92374.1 - 1.1 9.7 5.0 1.4 9.4 3.2 2.0 2 0 0 2 2 2 0 Phage terminase, small subunit PIN_12 PF16289.5 ORY92374.1 - 2.3 8.7 9.8 2.2 8.7 6.6 2.2 2 0 0 2 2 2 0 PIN domain DUF4208 PF13907.6 ORY92374.1 - 3.6 8.1 6.6 24 5.5 2.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) SPG4 PF17325.2 ORY92374.1 - 8.3 7.6 7.5 3.8 8.7 2.6 2.6 2 0 0 2 2 2 0 Stationary phase protein 4 zf-C2H2 PF00096.26 ORY92375.1 - 1e-11 44.6 8.3 2.5e-05 24.5 3.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY92375.1 - 1.2e-08 35.0 6.9 0.001 19.7 2.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY92375.1 - 5.7e-08 32.8 10.8 4.9e-05 23.6 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY92375.1 - 0.00037 20.7 2.7 0.11 12.8 0.3 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY92375.1 - 0.001 19.0 5.8 0.0026 17.7 1.2 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 ORY92375.1 - 0.0026 18.1 2.4 0.0039 17.5 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY92375.1 - 0.014 15.2 6.2 0.27 11.0 0.6 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 ORY92375.1 - 0.041 14.0 0.8 4.2 7.6 0.3 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 ORY92375.1 - 0.083 13.2 0.2 0.31 11.4 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY92375.1 - 0.13 12.6 1.2 0.5 10.7 0.5 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 ORY92375.1 - 0.26 11.2 6.4 0.38 10.7 2.3 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain UBA PF00627.31 ORY92376.1 - 1.6e-11 43.8 0.1 1.2e-05 25.1 0.1 2.3 2 0 0 2 2 2 2 UBA/TS-N domain CUE PF02845.16 ORY92376.1 - 7.7e-06 25.5 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 2 CUE domain HOIP-UBA PF16678.5 ORY92376.1 - 1.9e-05 24.7 0.2 0.0057 16.7 0.1 2.3 2 0 0 2 2 2 2 HOIP UBA domain pair UBA_4 PF14555.6 ORY92376.1 - 5.1e-05 23.0 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 UBA-like domain DUF1720 PF08226.11 ORY92376.1 - 0.014 15.8 29.7 0.014 15.8 29.7 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF1720) ArfGap PF01412.18 ORY92377.1 - 2e-34 118.1 0.0 2.6e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CoA_transf_3 PF02515.17 ORY92378.1 - 4.5e-71 239.9 0.0 1.3e-70 238.4 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III Clp_N PF02861.20 ORY92378.1 - 0.068 13.3 0.7 44 4.3 0.0 3.9 5 0 0 5 5 5 0 Clp amino terminal domain, pathogenicity island component Peptidase_M76 PF09768.9 ORY92379.1 - 1e-22 80.7 0.1 1.2e-22 80.5 0.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 ORY92379.1 - 0.00011 22.0 0.2 0.00019 21.3 0.1 1.6 1 1 0 1 1 1 1 SprT-like family Tox-MPTase2 PF15638.6 ORY92379.1 - 0.007 16.1 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase toxin 2 Peptidase_M78 PF06114.13 ORY92379.1 - 0.043 13.7 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 IrrE N-terminal-like domain MutS_III PF05192.18 ORY92379.1 - 0.098 12.9 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 MutS domain III DUF2268 PF10026.9 ORY92379.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Peptidase_M91 PF14891.6 ORY92379.1 - 0.15 12.4 0.0 0.15 12.4 0.0 1.3 1 1 0 1 1 1 0 Effector protein PX PF00787.24 ORY92380.1 - 1.2e-19 70.3 1.7 2.9e-19 69.1 1.7 1.7 1 0 0 1 1 1 1 PX domain SUIM_assoc PF16619.5 ORY92380.1 - 0.012 15.7 6.2 0.012 15.7 6.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Smg8_Smg9 PF10220.9 ORY92380.1 - 0.23 9.7 11.4 0.01 14.2 4.9 1.8 2 0 0 2 2 2 0 Smg8_Smg9 ALMT PF11744.8 ORY92380.1 - 0.43 9.3 9.2 0.52 9.1 1.2 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter dsRBD2 PF17842.1 ORY92380.1 - 0.64 10.2 4.6 7.8 6.7 4.6 2.6 1 1 0 1 1 1 0 Double-stranded RNA binding domain 2 Spt20 PF12090.8 ORY92380.1 - 0.72 9.4 13.3 1.8 8.2 13.3 1.6 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 ORY92380.1 - 1.2 7.8 3.2 2.1 7.0 3.2 1.3 1 0 0 1 1 1 0 Presenilin HflK_N PF12221.8 ORY92380.1 - 1.3 9.1 6.3 18 5.5 0.1 4.1 3 1 0 3 3 3 0 Bacterial membrane protein N terminal Androgen_recep PF02166.16 ORY92380.1 - 1.8 7.4 10.9 3.5 6.3 10.9 1.4 1 0 0 1 1 1 0 Androgen receptor DUF4578 PF15147.6 ORY92380.1 - 2.1 9.2 11.2 0.052 14.4 4.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4578) SPG4 PF17325.2 ORY92380.1 - 3.7 8.7 7.5 1.1 10.4 3.7 2.1 2 0 0 2 2 1 0 Stationary phase protein 4 FidL_like PF15941.5 ORY92984.1 - 0.12 12.9 0.3 0.46 11.0 0.0 1.8 2 0 0 2 2 2 0 FidL-like putative membrane protein Sugar_tr PF00083.24 ORY92985.1 - 2.8e-94 316.5 14.1 2.6e-93 313.3 14.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY92985.1 - 6.3e-24 84.6 43.7 1.2e-15 57.4 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY92985.1 - 4.4e-10 38.7 28.5 1.3e-05 23.9 6.4 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein MFS_4 PF06779.14 ORY92985.1 - 0.00045 19.6 12.8 0.00045 19.6 12.8 2.8 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ORY92985.1 - 0.058 11.7 2.5 1.7 6.9 2.4 2.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 ORY92985.1 - 0.57 8.5 14.1 0.014 13.9 5.8 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) PIGA PF08288.12 ORY92986.1 - 1e-43 147.8 0.3 2.2e-43 146.8 0.3 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 ORY92986.1 - 5.6e-28 98.0 0.3 9.7e-28 97.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ORY92986.1 - 1.3e-23 83.4 0.0 2.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY92986.1 - 3.4e-20 72.9 0.3 1.4e-19 70.9 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY92986.1 - 4.2e-10 40.3 0.0 8.4e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 ORY92986.1 - 4.6e-06 26.7 0.1 7.4e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 ORY92986.1 - 0.029 14.1 0.0 0.09 12.4 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Sulfate_transp PF00916.20 ORY92988.1 - 1.7e-62 211.4 18.9 2.9e-62 210.6 18.9 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 ORY92988.1 - 2.8e-15 56.2 0.0 4.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 ORY92988.1 - 6.6e-09 35.4 0.0 1.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 STAS domain Shisa PF13908.6 ORY92988.1 - 0.43 10.8 1.3 1.1 9.4 1.3 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PALP PF00291.25 ORY92989.1 - 3.2e-60 204.0 0.2 4e-60 203.7 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FtsZ_C PF12327.8 ORY92989.1 - 0.13 12.6 0.1 0.92 9.9 0.0 2.3 2 1 0 2 2 2 0 FtsZ family, C-terminal domain FancD2 PF14631.6 ORY92990.1 - 4.4e-220 733.6 19.3 1.1e-163 546.7 10.6 2.3 1 1 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 ORY92990.1 - 0.092 13.1 5.9 0.32 11.3 0.0 3.9 3 1 1 4 4 4 0 FANCI solenoid 2 Cyclin_N PF00134.23 ORY92992.1 - 1.4e-12 47.5 0.0 4e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 ORY92992.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 ORY92992.1 - 0.031 14.3 0.0 0.13 12.4 0.0 2.0 3 0 0 3 3 3 0 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORY92992.1 - 0.075 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Cyclin, C-terminal domain Gram_pos_anchor PF00746.21 ORY92993.1 - 0.094 12.7 0.4 0.094 12.7 0.4 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif RAI1 PF08652.11 ORY92994.1 - 7.2e-28 96.6 0.2 2.7e-27 94.7 0.0 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease eIF-3_zeta PF05091.12 ORY92994.1 - 0.0083 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Bax1-I PF01027.20 ORY92995.1 - 0.0089 15.9 4.2 0.012 15.5 4.2 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 COX2-transmemb PF09125.10 ORY92995.1 - 0.34 10.8 2.1 0.41 10.5 0.3 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane VTC PF09359.10 ORY92996.1 - 8.2e-13 48.4 0.5 7.2e-12 45.3 0.0 2.7 2 1 0 2 2 2 1 VTC domain DUF202 PF02656.15 ORY92996.1 - 4.1e-11 43.2 2.7 4.1e-11 43.2 2.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) YkuI_C PF10388.9 ORY92996.1 - 0.12 12.1 2.7 1.3 8.8 0.2 2.7 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain Peptidase_S49_N PF08496.10 ORY92996.1 - 0.43 10.6 3.2 1.2 9.2 3.2 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-HC5HC2H PF13771.6 ORY92997.1 - 8.7e-11 41.9 1.9 8.7e-11 41.9 1.9 4.1 3 1 1 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORY92997.1 - 1.2e-08 35.1 3.3 1.2e-08 35.1 3.3 3.4 3 1 2 5 5 5 1 PHD-zinc-finger like domain N6_N4_Mtase PF01555.18 ORY92997.1 - 2.2e-08 34.1 0.0 0.016 14.9 0.0 3.6 3 0 0 3 3 3 2 DNA methylase MBT PF02820.18 ORY92997.1 - 0.00013 22.3 0.2 0.15 12.4 0.0 3.1 2 0 0 2 2 2 2 mbt repeat Tudor_4 PF18358.1 ORY92997.1 - 0.0031 17.1 1.1 0.0031 17.1 1.1 3.8 4 0 0 4 4 4 1 Histone methyltransferase Tudor domain Agenet PF05641.12 ORY92997.1 - 0.0043 17.5 8.6 0.11 12.9 0.1 4.3 4 0 0 4 4 4 2 Agenet domain ZZ PF00569.17 ORY92997.1 - 0.0043 16.8 3.9 0.0043 16.8 3.9 3.8 3 1 0 3 3 3 2 Zinc finger, ZZ type AT_hook PF02178.19 ORY92997.1 - 0.0044 16.7 28.5 0.47 10.5 5.3 4.2 3 0 0 3 3 3 3 AT hook motif Cript PF10235.9 ORY92997.1 - 0.12 12.9 8.2 0.19 12.3 0.2 3.4 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Na_sulph_symp PF00939.19 ORY92998.1 - 2.9e-93 313.5 16.9 3.7e-93 313.1 16.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 ORY92998.1 - 3.1e-15 56.2 34.4 1.5e-14 53.9 13.5 2.4 1 1 1 2 2 2 2 Citrate transporter PADR1 PF08063.12 ORY92998.1 - 3.6 7.4 4.3 2.2 8.1 0.9 2.4 3 0 0 3 3 3 0 PADR1 (NUC008) domain Phos_pyr_kin PF08543.12 ORY92999.1 - 7.7e-20 71.3 0.0 1.1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ORY92999.1 - 5.7e-10 39.0 0.0 8.3e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase E1_dh PF00676.20 ORY93001.1 - 2.4e-95 318.9 0.0 2.9e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ORY93001.1 - 0.00012 21.9 0.2 0.0011 18.7 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORY93001.1 - 0.0041 16.4 0.0 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase GspH PF12019.8 ORY93001.1 - 0.17 12.3 0.2 0.64 10.5 0.1 2.0 2 0 0 2 2 2 0 Type II transport protein GspH Tropomyosin_1 PF12718.7 ORY93002.1 - 0.011 15.9 4.9 0.011 15.9 4.9 2.4 2 1 0 2 2 2 0 Tropomyosin like ZapB PF06005.12 ORY93002.1 - 0.016 15.6 6.7 0.016 15.6 6.7 3.1 3 1 0 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 ORY93002.1 - 0.2 12.2 21.0 0.24 11.9 14.2 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 ORY93002.1 - 2 7.7 21.2 0.33 10.3 6.1 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 ORY93002.1 - 2.5 8.5 16.2 3.9 7.9 5.0 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 ORY93002.1 - 5.6 6.2 14.9 0.74 9.1 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HALZ PF02183.18 ORY93002.1 - 7.1 6.9 9.3 3.9 7.8 0.1 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Cnd1 PF12717.7 ORY93004.1 - 2.8e-54 183.5 4.8 1.1e-50 171.8 2.3 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 ORY93004.1 - 1.3e-40 138.9 0.1 7.7e-40 136.5 0.1 2.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 ORY93004.1 - 1.8e-10 41.1 0.2 0.0001 22.6 0.0 4.6 4 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 ORY93004.1 - 6.1e-08 32.3 2.7 4.3 7.9 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 ORY93004.1 - 3.7e-07 29.1 8.6 0.00013 20.7 0.5 4.2 4 1 0 4 4 4 2 Adaptin N terminal region Cnd3 PF12719.7 ORY93004.1 - 0.00019 20.7 1.0 0.00019 20.7 1.0 3.5 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 ORY93004.1 - 0.00062 20.2 0.8 6.4 7.4 0.0 4.9 6 0 0 6 6 5 1 HEAT-like repeat Arm_2 PF04826.13 ORY93004.1 - 0.0073 15.8 3.0 0.012 15.1 0.3 2.3 2 0 0 2 2 2 1 Armadillo-like RTP1_C1 PF10363.9 ORY93004.1 - 0.011 15.9 2.0 5.2 7.3 0.0 4.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cren7 PF11520.8 ORY93004.1 - 0.082 12.8 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Chromatin protein Cren7 DUF4404 PF14357.6 ORY93004.1 - 3.3 8.4 0.0 3.3 8.4 0.0 4.3 4 0 0 4 4 3 0 Domain of unknown function (DUF4404) ANAPC1 PF12859.7 ORY93006.1 - 9.1e-12 45.7 0.0 1.6e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 ORY93006.1 - 2.8e-11 43.2 5.7 0.0087 16.5 0.0 6.1 6 0 0 6 6 6 3 Proteasome/cyclosome repeat Phage_holin_3_1 PF05106.12 ORY93006.1 - 0.16 12.5 0.3 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Fis1_TPR_C PF14853.6 ORY93007.1 - 1.2e-23 82.9 0.1 1.9e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ORY93007.1 - 2.2e-12 46.4 0.0 3.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 ORY93007.1 - 0.00022 21.1 0.6 0.00046 20.1 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY93007.1 - 0.0092 16.7 0.1 0.23 12.4 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF357 PF04010.13 ORY93007.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TPR_19 PF14559.6 ORY93007.1 - 0.025 15.1 0.0 0.049 14.1 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat COPI_C PF06957.11 ORY93007.1 - 0.058 12.1 0.0 0.094 11.5 0.0 1.3 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Fungal_trans PF04082.18 ORY93008.1 - 3.1e-13 49.4 0.0 6.3e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY93008.1 - 3e-09 36.9 8.8 5.7e-09 35.9 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mei5 PF10376.9 ORY93008.1 - 0.16 11.8 0.4 0.27 11.1 0.4 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF775 PF05603.12 ORY93009.1 - 2.4e-59 200.3 0.1 2.7e-59 200.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) AMP-binding PF00501.28 ORY93010.1 - 1.1e-93 314.2 0.0 1.4e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY93010.1 - 4.1e-16 59.7 0.2 8.8e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CotH PF08757.11 ORY93011.1 - 1.6e-47 162.7 0.0 2.3e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 CotH kinase protein FbpA PF05833.11 ORY93012.1 - 1.7e-42 145.7 15.0 1.7e-42 145.7 15.0 2.9 3 0 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 ORY93012.1 - 1e-32 113.0 0.0 3.3e-32 111.4 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 ORY93012.1 - 3.4e-31 107.3 0.2 3.4e-31 107.3 0.2 4.4 4 1 1 5 5 5 1 NFACT protein C-terminal domain Sec63 PF02889.16 ORY93013.1 - 6.1e-145 481.1 0.1 6e-79 264.8 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORY93013.1 - 3.6e-51 173.4 0.1 5.2e-26 91.5 0.5 3.7 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.15 ORY93013.1 - 2.8e-24 86.0 0.0 1.6e-11 44.5 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY93013.1 - 6.1e-17 62.0 0.0 1.4e-06 28.6 0.0 4.0 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY93013.1 - 7.3e-06 26.3 2.7 0.12 12.7 0.0 4.3 3 2 0 3 3 3 2 AAA domain AAA PF00004.29 ORY93013.1 - 1.7e-05 25.3 0.8 0.17 12.3 0.0 3.9 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 ORY93013.1 - 2e-05 24.7 0.1 2e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 N-terminal helicase PWI domain GARS_N PF02844.15 ORY93013.1 - 0.058 14.2 0.2 32 5.4 0.0 3.4 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain IstB_IS21 PF01695.17 ORY93013.1 - 0.074 12.8 0.1 7.2 6.3 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_11 PF13086.6 ORY93013.1 - 1.4 8.7 9.1 17 5.1 0.0 4.3 3 1 1 4 4 4 0 AAA domain Gp_dh_C PF02800.20 ORY93014.1 - 1.1e-67 226.5 0.1 1.7e-67 225.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORY93014.1 - 2.2e-39 133.9 0.0 4.5e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORY93014.1 - 0.088 12.9 0.0 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Aconitase PF00330.20 ORY93017.1 - 8.8e-153 509.6 0.0 1.2e-152 509.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY93017.1 - 8e-44 149.1 0.0 1.6e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Arf PF00025.21 ORY93018.1 - 4.1e-48 163.1 0.0 5.1e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY93018.1 - 2.3e-12 47.2 0.0 5e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY93018.1 - 8.1e-12 45.0 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY93018.1 - 4.3e-11 42.6 0.1 7.4e-08 31.9 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY93018.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORY93018.1 - 1.5e-08 34.4 0.0 7e-06 25.7 0.0 2.0 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY93018.1 - 1.7e-08 34.5 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY93018.1 - 1.1e-06 28.2 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.6 ORY93018.1 - 0.0099 16.4 0.0 0.012 16.1 0.0 1.2 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 ORY93018.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 ORY93018.1 - 0.023 15.2 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ORY93018.1 - 0.039 13.7 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2672 PF10878.8 ORY93018.1 - 0.04 13.9 0.4 4.1 7.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) AAA_22 PF13401.6 ORY93018.1 - 0.063 13.6 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Thioredoxin_3 PF13192.6 ORY93018.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain AAA_29 PF13555.6 ORY93018.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 ORY93020.1 - 5.3e-49 167.0 0.0 7.1e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93020.1 - 1.4e-24 86.8 0.0 2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY93020.1 - 2.7e-06 26.6 0.1 3.9e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY93020.1 - 1.1e-05 25.5 0.5 4e-05 23.7 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY93020.1 - 0.0016 18.1 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 ORY93020.1 - 0.017 14.4 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 ORY93020.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 ORY93020.1 - 0.079 12.5 0.2 0.2 11.2 0.2 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Shisa PF13908.6 ORY93021.1 - 0.0021 18.3 0.1 0.0021 18.3 0.1 2.5 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator 7TM_GPCR_Srsx PF10320.9 ORY93021.1 - 0.004 16.6 5.6 0.004 16.6 5.6 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4381 PF14316.6 ORY93021.1 - 0.06 13.6 0.2 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) WBP-1 PF11669.8 ORY93021.1 - 0.14 12.8 0.5 0.92 10.2 0.3 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 7tm_1 PF00001.21 ORY93021.1 - 0.99 8.7 11.9 5.2 6.3 12.0 2.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Peptidase_C12 PF01088.21 ORY93022.1 - 6.9e-50 169.7 0.0 8.6e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF872 PF05915.12 ORY93023.1 - 6.4e-17 61.8 0.2 7.5e-17 61.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) YrhK PF14145.6 ORY93023.1 - 0.0056 16.5 2.6 0.02 14.8 0.4 2.1 2 0 0 2 2 2 1 YrhK-like protein DUF3040 PF11239.8 ORY93023.1 - 0.013 15.8 0.8 0.035 14.4 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Arc_PepC_II PF06847.11 ORY93023.1 - 0.079 13.5 0.1 0.1 13.2 0.1 1.4 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Pox_I5 PF04713.12 ORY93023.1 - 0.099 12.7 4.5 0.2 11.7 4.5 1.5 1 1 0 1 1 1 0 Poxvirus protein I5 ABC_membrane PF00664.23 ORY93025.1 - 2.4e-104 348.8 28.7 4.6e-55 187.2 14.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY93025.1 - 4.3e-69 231.3 0.1 1.9e-34 119.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY93025.1 - 1.7e-13 50.5 0.0 1.8e-05 24.3 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY93025.1 - 6e-10 39.8 4.9 0.0007 20.0 0.0 3.7 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 ORY93025.1 - 6.1e-09 35.2 0.3 0.0027 16.6 0.1 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORY93025.1 - 9.4e-09 35.7 1.4 0.0061 16.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORY93025.1 - 1.3e-06 28.1 0.2 0.027 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY93025.1 - 2.9e-06 27.3 0.0 0.13 12.1 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_30 PF13604.6 ORY93025.1 - 8.3e-06 25.6 0.7 0.23 11.2 0.2 3.6 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY93025.1 - 0.00011 22.7 0.0 0.61 10.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 ORY93025.1 - 0.00014 21.2 0.0 0.11 11.7 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 ORY93025.1 - 0.00018 21.0 0.0 0.071 12.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 ORY93025.1 - 0.00021 21.3 0.0 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 ORY93025.1 - 0.00023 21.4 0.1 1 9.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 ORY93025.1 - 0.00036 20.4 1.5 0.14 11.8 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 ORY93025.1 - 0.00042 20.5 5.6 0.5 10.6 0.6 4.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 ORY93025.1 - 0.00068 19.5 0.4 2.1 8.1 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 ORY93025.1 - 0.00094 18.5 3.3 0.054 12.8 0.0 3.2 4 0 0 4 4 4 1 Zeta toxin AAA_5 PF07728.14 ORY93025.1 - 0.0013 18.8 2.5 1.7 8.6 0.0 4.1 4 1 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY93025.1 - 0.0017 18.0 0.1 1.2 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ORY93025.1 - 0.0029 17.9 0.0 5.2 7.5 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 ORY93025.1 - 0.0037 17.4 0.0 3.7 7.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY93025.1 - 0.0054 16.5 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 ORY93025.1 - 0.0084 15.7 0.0 1.1 8.8 0.0 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF87 PF01935.17 ORY93025.1 - 0.0096 16.0 1.1 6.1 6.9 0.0 3.1 3 0 0 3 3 2 0 Helicase HerA, central domain PRK PF00485.18 ORY93025.1 - 0.019 14.7 0.1 8.8 6.0 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 ORY93025.1 - 0.028 14.9 7.2 15 6.0 0.3 4.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Tim54 PF11711.8 ORY93025.1 - 0.041 12.7 1.5 0.15 10.8 0.1 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 APS_kinase PF01583.20 ORY93025.1 - 0.041 13.8 0.7 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 ORY93025.1 - 0.045 13.8 1.4 8.8 6.5 0.0 3.3 3 1 0 3 3 3 0 50S ribosome-binding GTPase NACHT PF05729.12 ORY93025.1 - 0.076 12.9 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 ORY93025.1 - 0.08 12.6 0.2 11 5.6 0.2 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4157 PF13699.6 ORY93025.1 - 0.11 12.7 0.1 0.36 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) IstB_IS21 PF01695.17 ORY93025.1 - 0.16 11.7 2.9 26 4.5 0.0 3.9 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF4710 PF15828.5 ORY93025.1 - 5.2 7.3 6.1 1.8e+02 2.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) PIEZO PF15917.5 ORY93025.1 - 10 5.6 13.5 1.5 8.3 2.7 2.3 2 0 0 2 2 2 0 Piezo Metallophos PF00149.28 ORY93026.1 - 3.4e-16 60.3 4.7 5e-16 59.8 4.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY93026.1 - 3.4e-06 27.3 0.1 6.9e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CCCH PF00642.24 ORY93027.1 - 2.3e-12 46.5 35.4 0.0026 17.6 4.0 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY93027.1 - 6.9e-06 25.9 33.8 0.043 13.9 1.0 5.9 5 2 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 ORY93027.1 - 0.015 15.1 28.6 0.016 15.0 0.2 5.3 5 0 0 5 5 5 0 CCCH-type zinc finger Defensin_beta PF00711.19 ORY93027.1 - 0.043 13.8 0.5 0.043 13.8 0.5 3.3 4 0 0 4 4 4 0 Beta defensin zf-CCCH_3 PF15663.5 ORY93027.1 - 0.053 13.7 19.9 0.075 13.2 2.8 3.5 1 1 2 3 3 3 0 Zinc-finger containing family MucBP_2 PF17965.1 ORY93027.1 - 1.8 9.2 4.3 0.91 10.1 1.3 2.1 2 0 0 2 2 2 0 Mucin binding domain UPF0203 PF05254.12 ORY93028.1 - 2.2e-27 95.1 1.7 2.6e-27 94.8 1.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 ORY93028.1 - 0.0022 18.3 1.1 0.005 17.2 1.1 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 ORY93028.1 - 0.0037 17.4 1.1 0.0064 16.7 1.1 1.4 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 ORY93028.1 - 0.013 16.4 1.7 0.25 12.2 0.2 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5339) CHCH PF06747.13 ORY93028.1 - 0.036 14.2 2.5 0.3 11.3 2.8 2.1 1 1 1 2 2 2 0 CHCH domain CX9C PF16860.5 ORY93028.1 - 0.078 13.0 0.3 7.6 6.6 0.0 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 ORY93028.1 - 0.19 12.1 2.0 2.1 8.8 2.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Cmc1 PF08583.10 ORY93028.1 - 0.23 11.5 3.7 4.8 7.3 0.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Lipase_GDSL_2 PF13472.6 ORY93029.1 - 2e-09 38.1 0.1 2.6e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HA2 PF04408.23 ORY93030.1 - 1.7e-21 76.5 0.0 3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY93030.1 - 1.2e-17 64.1 0.0 2.7e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY93030.1 - 2.6e-13 50.3 0.0 4.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Spermine_synth PF01564.17 ORY93033.1 - 1e-70 237.0 0.1 5.8e-70 234.5 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ORY93033.1 - 1.6e-23 82.3 0.1 2.7e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 ORY93033.1 - 0.00012 22.7 0.0 0.00027 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY93033.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 ORY93033.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 ORY93033.1 - 0.022 15.5 0.1 0.092 13.5 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain SLC35F PF06027.12 ORY93034.1 - 5.4e-91 305.2 24.4 6.3e-91 305.0 24.4 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 ORY93034.1 - 1.1e-08 35.3 29.5 0.00013 22.2 6.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 ORY93034.1 - 7.3e-07 28.4 2.7 7.3e-07 28.4 2.7 2.3 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PLDc PF00614.22 ORY93035.1 - 1.2e-16 60.1 1.8 6.3e-10 38.8 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORY93035.1 - 1.4e-14 54.2 0.1 1.1e-07 31.8 0.2 3.1 2 1 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.8 ORY93035.1 - 0.095 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB RPA43_OB PF17875.1 ORY93036.1 - 1.8e-26 93.2 4.0 1.3e-25 90.4 0.2 2.1 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 ORY93036.1 - 2.2e-10 40.8 0.0 4.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PaREP1 PF05942.11 ORY93036.1 - 0.11 12.4 2.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Pap_E4 PF02711.14 ORY93036.1 - 0.31 12.0 8.8 6.8 7.7 0.3 2.3 2 0 0 2 2 2 0 E4 protein Connexin PF00029.19 ORY93036.1 - 1 9.1 3.7 6.1 6.5 2.5 2.0 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 ORY93036.1 - 1.2 9.3 7.9 12 6.1 4.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Sporozoite_P67 PF05642.11 ORY93036.1 - 4.1 5.4 12.3 4 5.4 0.8 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen FAM176 PF14851.6 ORY93036.1 - 4.4 6.9 10.1 2.2 8.0 0.7 2.1 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.8 ORY93036.1 - 6.4 5.4 8.7 1.2 7.8 1.6 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Polysacc_deac_1 PF01522.21 ORY93037.1 - 1.5e-08 34.6 0.0 3.1e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase ABC_tran PF00005.27 ORY93038.1 - 1.7e-28 99.9 0.0 3.9e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY93038.1 - 1.6e-21 76.7 37.4 1e-15 57.8 14.6 3.3 3 1 1 4 4 4 2 ABC-2 type transporter AAA_21 PF13304.6 ORY93038.1 - 0.00012 22.1 0.1 0.37 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 ORY93038.1 - 0.00039 21.0 0.0 0.00094 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY93038.1 - 0.0018 18.0 0.4 0.0039 16.9 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ORY93038.1 - 0.0058 16.1 0.0 0.16 11.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY93038.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 ORY93038.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Abhydrolase_5 PF12695.7 ORY93038.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_28 PF13521.6 ORY93038.1 - 0.03 14.6 0.6 0.074 13.3 0.6 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY93038.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY93038.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 ORY93038.1 - 0.038 13.5 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_30 PF13604.6 ORY93038.1 - 0.039 13.7 3.6 2.3 7.9 0.2 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ORY93038.1 - 0.053 13.9 0.4 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 ORY93038.1 - 0.071 12.7 0.4 0.18 11.3 0.4 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 ORY93038.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Hist_deacetyl PF00850.19 ORY93039.1 - 1.3e-56 192.3 0.1 6.7e-56 190.0 0.1 2.0 1 1 0 1 1 1 1 Histone deacetylase domain Tudor-knot PF11717.8 ORY93039.1 - 0.092 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain PDZ_1 PF12812.7 ORY93040.1 - 3.1e-31 107.2 0.0 1.1e-20 73.4 0.0 3.5 3 0 0 3 3 3 3 PDZ-like domain PDZ_6 PF17820.1 ORY93040.1 - 2.6e-19 68.8 0.5 7.9e-06 25.6 0.0 4.9 4 0 0 4 4 4 4 PDZ domain Trypsin_2 PF13365.6 ORY93040.1 - 2.4e-17 64.2 0.1 2.1e-14 54.6 0.0 3.2 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ORY93040.1 - 1.2e-13 51.2 0.0 0.001 19.3 0.0 4.2 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORY93040.1 - 2.4e-11 43.8 0.2 0.0072 16.7 0.0 3.5 3 0 0 3 3 3 3 PDZ domain Trypsin PF00089.26 ORY93040.1 - 0.027 14.3 0.0 0.073 12.9 0.0 1.7 1 1 0 1 1 1 0 Trypsin Peptidase_S3 PF00944.19 ORY93040.1 - 0.13 12.1 0.1 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Alphavirus core protein Tricorn_PDZ PF14685.6 ORY93040.1 - 0.18 11.8 0.0 0.94 9.5 0.0 2.2 1 0 0 1 1 1 0 Tricorn protease PDZ domain CAF1C_H4-bd PF12265.8 ORY93041.1 - 1.5e-26 92.5 0.8 3.1e-26 91.4 0.2 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORY93041.1 - 2.5e-23 81.9 7.9 1.8e-05 25.4 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Ecl1 PF12855.7 ORY93042.1 - 9.4e-12 46.4 21.4 1.2e-11 46.1 21.4 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 ORY93042.1 - 0.0034 17.4 0.9 0.0079 16.3 0.9 1.6 1 0 0 1 1 1 1 MYND finger ANF_receptor PF01094.28 ORY93043.1 - 2.8e-29 102.3 2.2 3.6e-29 102.0 2.2 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY93043.1 - 1.6e-13 51.1 4.3 2.3e-13 50.5 4.3 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY93044.1 - 3e-11 43.5 11.5 4e-11 43.1 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Saf_2TM PF18303.1 ORY93044.1 - 0.16 11.5 4.8 0.038 13.6 1.4 1.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Tetraspanin PF00335.20 ORY93044.1 - 0.66 9.6 5.9 0.14 11.8 2.6 1.7 2 1 0 2 2 2 0 Tetraspanin family UcrQ PF02939.16 ORY93045.1 - 1.2e-33 114.9 0.7 1.4e-33 114.7 0.7 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 ORY93045.1 - 0.00028 21.2 0.1 0.00038 20.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 TPT PF03151.16 ORY93046.1 - 1.8e-34 119.4 17.2 2.1e-34 119.2 17.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY93046.1 - 1.2e-10 41.7 24.5 3.1e-06 27.4 11.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY93046.1 - 4.1e-10 39.4 23.4 6.1e-10 38.8 23.4 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 ORY93046.1 - 0.42 9.7 17.5 14 4.8 17.5 2.2 1 1 0 1 1 1 0 Nucleotide-sugar transporter ATP11 PF06644.11 ORY93047.1 - 4.9e-70 236.4 10.1 5.8e-70 236.2 10.1 1.0 1 0 0 1 1 1 1 ATP11 protein Presenilin PF01080.17 ORY93047.1 - 0.15 10.8 1.1 0.18 10.6 1.1 1.1 1 0 0 1 1 1 0 Presenilin GNAT_acetyltr_2 PF13718.6 ORY93047.1 - 0.18 11.2 4.9 0.28 10.5 4.9 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 GTA_holin_3TM PF11351.8 ORY93047.1 - 1.3 9.6 8.6 3.1 8.4 8.6 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Glyco_hydro_15 PF00723.21 ORY93049.1 - 6.5e-132 440.5 0.0 7.9e-132 440.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 ORY93049.1 - 8.3e-21 74.3 0.0 2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Interleukin-like EMT inducer COPI_assoc PF08507.10 ORY93050.1 - 0.00048 20.2 2.3 0.00057 19.9 2.3 1.1 1 0 0 1 1 1 1 COPI associated protein Nodulin_late PF07127.11 ORY93050.1 - 0.52 10.7 2.2 0.54 10.6 0.4 1.9 1 1 1 2 2 2 0 Late nodulin protein COPI_assoc PF08507.10 ORY93051.1 - 7.6e-05 22.8 0.0 9.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 COPI associated protein COX4 PF02936.14 ORY93051.1 - 0.036 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Kelch_4 PF13418.6 ORY93052.1 - 6.4e-44 147.7 8.9 1.6e-09 37.6 0.0 6.2 4 2 2 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY93052.1 - 5.1e-43 144.6 7.5 4.1e-07 30.1 0.1 6.5 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY93052.1 - 8.5e-41 137.3 1.8 1.8e-07 30.6 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 ORY93052.1 - 4.8e-39 131.7 6.4 8.8e-08 32.0 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 ORY93052.1 - 1.2e-36 123.8 9.2 2.4e-06 27.6 0.1 6.2 3 3 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 ORY93052.1 - 1.1e-33 113.9 2.3 1.5e-05 24.7 0.0 6.3 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.6 ORY93052.1 - 1 9.9 11.2 5.9 7.5 0.1 4.9 5 1 1 6 6 6 0 PQQ-like domain RIO1 PF01163.22 ORY93056.1 - 3.5e-48 163.7 0.0 8.2e-48 162.5 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 ORY93056.1 - 4.3e-35 119.8 0.1 9.5e-35 118.7 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 ORY93056.1 - 1.7e-11 44.5 0.1 2.6e-05 24.3 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY93056.1 - 2.1e-06 27.2 0.0 0.00015 21.2 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY93056.1 - 0.094 12.0 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like TFIIF_alpha PF05793.12 ORY93056.1 - 2.8 6.4 43.3 3.8 6.0 43.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 ORY93056.1 - 5.2 6.3 33.2 8.1 5.7 33.2 1.3 1 0 0 1 1 1 0 BUD22 RRM_1 PF00076.22 ORY93057.1 - 6.5e-85 279.0 0.4 1.3e-22 79.4 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY93057.1 - 4.4e-20 71.6 0.2 4.4e-20 71.6 0.2 2.0 2 0 0 2 2 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORY93057.1 - 1.9e-12 46.8 0.0 0.063 12.9 0.0 4.4 2 1 2 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY93057.1 - 1.4e-06 28.2 5.7 0.086 12.9 0.0 3.7 3 1 1 4 4 4 2 RNA binding motif SET_assoc PF11767.8 ORY93057.1 - 1.2e-05 24.9 0.1 0.37 10.4 0.0 3.8 4 0 0 4 4 4 2 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 ORY93057.1 - 3.5e-05 23.7 0.1 1.5 8.9 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY93057.1 - 7.3e-05 22.8 0.1 5.3 7.2 0.0 4.8 4 1 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 ORY93057.1 - 0.00014 21.9 4.0 1.1 9.3 0.4 4.5 4 0 0 4 4 4 1 Limkain b1 OB_RNB PF08206.11 ORY93057.1 - 0.00024 20.7 2.9 0.52 10.0 0.0 3.7 4 0 0 4 4 4 2 Ribonuclease B OB domain RRM_occluded PF16842.5 ORY93057.1 - 0.067 13.1 0.0 0.79 9.6 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif DbpA PF03880.15 ORY93057.1 - 0.16 12.0 0.1 52 3.9 0.0 3.3 3 0 0 3 3 3 0 DbpA RNA binding domain Nab6_mRNP_bdg PF10567.9 ORY93057.1 - 0.17 11.3 1.9 24 4.3 0.0 2.7 2 0 0 2 2 2 0 RNA-recognition motif UPF0524 PF15823.5 ORY93057.1 - 2.5 7.5 5.5 1.6 8.1 3.1 1.9 2 0 0 2 2 2 0 UPF0524 of C3orf70 EPL1 PF10513.9 ORY93057.1 - 5.5 7.4 18.2 0.15 12.5 9.4 2.7 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF572 PF04502.13 ORY93057.1 - 9.1 5.8 15.1 0.23 11.0 7.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) TMEM173 PF15009.6 ORY93058.1 - 0.0065 15.7 1.2 0.008 15.4 1.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 DUF2109 PF09882.9 ORY93058.1 - 0.038 14.0 0.7 0.07 13.1 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) Tht1 PF04163.12 ORY93059.1 - 3.6e-09 36.0 1.3 1.1e-08 34.4 0.1 1.9 1 1 0 2 2 2 1 Tht1-like nuclear fusion protein TPD52 PF04201.15 ORY93059.1 - 0.29 10.7 8.8 0.84 9.2 0.5 2.6 2 1 0 2 2 2 0 Tumour protein D52 family Transcrip_act PF04949.13 ORY93059.1 - 0.76 9.6 4.2 2.3 8.1 0.1 3.0 3 1 0 3 3 3 0 Transcriptional activator Csm1_N PF18504.1 ORY93059.1 - 7.6 7.0 13.9 0.21 11.9 0.5 3.9 4 0 0 4 4 4 0 Csm1 N-terminal domain HNF-1_N PF04814.13 ORY93060.1 - 0.0061 17.2 0.5 0.011 16.4 0.5 1.4 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus GoLoco PF02188.17 ORY93060.1 - 0.3 10.7 5.5 8.2 6.1 0.2 3.4 3 0 0 3 3 3 0 GoLoco motif Glycos_transf_1 PF00534.20 ORY93061.1 - 1.5e-30 106.0 0.0 2.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY93061.1 - 1.1e-25 90.6 0.9 1.9e-25 89.8 0.3 1.7 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ORY93061.1 - 1.5e-24 86.9 0.1 2.9e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY93061.1 - 2.4e-14 54.1 0.7 2.4e-14 54.1 0.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ORY93061.1 - 3.5e-08 33.7 0.0 7.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 FYRN PF05964.14 ORY93062.1 - 1.2e-19 69.8 1.5 3.5e-19 68.4 1.5 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY93062.1 - 5.8e-14 52.0 0.0 1.5e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus SPX PF03105.19 ORY93062.1 - 0.015 15.3 4.2 0.013 15.5 4.2 1.2 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 ORY93062.1 - 0.39 9.4 9.0 0.51 9.0 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 ORY93062.1 - 0.59 8.8 8.2 0.83 8.4 8.2 1.1 1 0 0 1 1 1 0 Presenilin Synthase_beta PF11421.8 ORY93062.1 - 1.7 9.4 10.2 2.3 9.0 0.2 2.7 2 0 0 2 2 2 0 ATP synthase F1 beta subunit HMG_box PF00505.19 ORY93063.1 - 5.5e-06 26.7 0.2 5.5e-06 26.7 0.2 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY93063.1 - 0.00052 20.6 0.7 0.0013 19.3 0.7 1.8 1 0 0 1 1 1 1 HMG-box domain MFS_2 PF13347.6 ORY93064.1 - 3.8e-12 45.5 2.7 3.8e-12 45.5 2.7 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.15 ORY93064.1 - 3.2e-08 33.0 0.2 1.1e-07 31.3 0.2 1.8 1 0 0 1 1 1 1 PUCC protein MFS_1_like PF12832.7 ORY93064.1 - 0.0013 17.6 0.0 0.011 14.6 0.0 2.4 1 1 0 1 1 1 1 MFS_1 like family O-antigen_lig PF13425.6 ORY93064.1 - 0.66 8.7 4.0 0.43 9.3 0.6 2.3 3 1 0 3 3 3 0 O-antigen ligase like membrane protein DUF2434 PF10361.9 ORY93065.1 - 0.024 13.6 0.2 0.043 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Glyco_transf_28 PF03033.20 ORY93066.1 - 3.6e-29 101.6 0.0 8.4e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 ORY93066.1 - 1.6e-25 89.2 6.6 2.6e-18 65.9 1.1 3.3 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 ORY93066.1 - 5e-10 39.8 0.9 2e-09 37.9 0.1 2.6 3 0 0 3 3 3 1 PH domain UDPGT PF00201.18 ORY93066.1 - 7.8e-08 31.6 0.0 1.6e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 ORY93066.1 - 0.00014 22.1 0.1 0.00037 20.7 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_TFIIH PF08567.11 ORY93066.1 - 0.15 12.4 0.0 15 6.0 0.0 3.1 3 0 0 3 3 3 0 TFIIH p62 subunit, N-terminal domain PH_11 PF15413.6 ORY93066.1 - 0.5 10.8 3.8 2.7 8.4 0.5 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain ECR1_N PF14382.6 ORY93067.1 - 1.3e-14 53.7 0.2 2.6e-14 52.7 0.2 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 ORY93067.1 - 1.8e-13 50.6 0.0 5.8e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 KH domain EXOSC1 PF10447.9 ORY93067.1 - 0.00071 20.2 0.2 0.21 12.2 0.1 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 Cyto_heme_lyase PF01265.17 ORY93068.1 - 9.5e-61 205.9 9.5 2.8e-59 201.1 9.5 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Sugar_tr PF00083.24 ORY93069.1 - 6.9e-57 193.3 18.7 9.2e-57 192.9 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY93069.1 - 3.8e-30 105.0 52.1 2.2e-25 89.3 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_1 PF00036.32 ORY93070.1 - 7.1e-35 116.0 9.4 8.8e-08 31.2 0.0 4.7 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.6 ORY93070.1 - 1.3e-32 112.0 3.8 1.5e-15 57.4 2.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY93070.1 - 3.7e-28 95.0 7.3 9.3e-08 31.4 0.1 5.0 4 2 2 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 ORY93070.1 - 2.1e-25 87.0 13.1 1.9e-07 30.3 0.0 5.1 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 ORY93070.1 - 1.3e-23 82.6 9.5 1.2e-10 41.1 0.5 4.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY93070.1 - 3.8e-11 43.3 0.5 1.9e-06 28.1 0.9 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY93070.1 - 8.7e-09 35.3 3.4 0.0005 20.0 0.1 2.6 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY93070.1 - 8.2e-07 29.3 0.1 0.00089 19.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 ORY93070.1 - 3.7e-05 23.8 4.1 0.29 11.4 0.4 3.4 2 2 2 4 4 4 2 Dockerin type I domain Caleosin PF05042.13 ORY93070.1 - 0.0005 20.0 0.1 1 9.3 0.0 3.2 2 2 1 3 3 3 2 Caleosin related protein TerB PF05099.13 ORY93070.1 - 0.0017 18.4 0.1 0.68 9.9 0.0 2.5 2 1 0 2 2 2 1 Tellurite resistance protein TerB DUF1636 PF07845.11 ORY93070.1 - 0.0021 18.5 0.0 5.2 7.5 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1636) EF-hand_10 PF14788.6 ORY93070.1 - 0.0027 17.5 1.4 6.3 6.7 0.3 3.5 3 0 0 3 3 3 1 EF hand EF-hand_11 PF08976.11 ORY93070.1 - 0.01 16.7 0.2 1 10.3 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 ORY93070.1 - 0.021 14.7 2.4 0.036 13.9 2.4 1.5 1 1 0 1 1 1 0 SurA N-terminal domain Acetyltransf_11 PF13720.6 ORY93070.1 - 0.12 12.8 0.0 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Aldo_ket_red PF00248.21 ORY93071.1 - 1.8e-45 155.4 0.0 2.4e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF325 PF03804.13 ORY93071.1 - 0.07 13.2 0.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Viral proteins of unknown function Ribosomal_S19 PF00203.21 ORY93072.1 - 3e-33 113.5 0.4 3.6e-33 113.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Peptidase_S28 PF05577.12 ORY93073.1 - 6e-14 51.7 0.1 7.6e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.12 ORY93074.1 - 9.4e-52 176.3 0.0 1.1e-51 176.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 ORY93074.1 - 1.5e-05 23.9 0.1 1.9e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 ORY93074.1 - 0.00043 20.0 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ras PF00071.22 ORY93075.1 - 2.9e-59 199.3 0.3 3.7e-59 199.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY93075.1 - 3e-33 114.6 0.1 4.4e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY93075.1 - 2.6e-16 59.6 0.1 3.1e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY93075.1 - 2.2e-07 30.9 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY93075.1 - 4.6e-07 29.4 0.0 5.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY93075.1 - 1.9e-06 27.5 0.0 4.1e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY93075.1 - 0.001 18.5 0.1 0.0024 17.3 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORY93075.1 - 0.0011 18.9 0.5 0.076 12.9 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 ORY93075.1 - 0.0017 17.9 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_24 PF13479.6 ORY93075.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORY93075.1 - 0.033 14.2 0.2 0.062 13.4 0.2 1.7 1 1 0 1 1 1 0 Dynamin family TniB PF05621.11 ORY93075.1 - 0.06 12.8 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein DNApol_Exo PF18136.1 ORY93075.1 - 0.079 12.1 0.1 0.094 11.8 0.1 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Septin PF00735.18 ORY93075.1 - 0.099 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 ORY93075.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 ORY93075.1 - 0.31 10.2 1.7 6 5.9 0.2 2.2 1 1 1 2 2 2 0 G-protein alpha subunit RTC PF01137.21 ORY93076.1 - 7.9e-54 182.2 0.0 9.4e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 ORY93076.1 - 1.3e-21 77.0 2.0 9.6e-12 45.3 0.4 2.3 1 1 1 2 2 2 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain LSM PF01423.22 ORY93077.1 - 7.3e-16 57.6 0.2 9.6e-16 57.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF5440 PF17509.2 ORY93077.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5440) AMP-binding PF00501.28 ORY93078.1 - 3.8e-75 253.1 0.0 4.8e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY93078.1 - 8.6e-09 36.3 0.0 2.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2_jaz PF12171.8 ORY93079.1 - 0.00084 19.6 2.6 0.0033 17.7 2.6 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORY93079.1 - 0.0012 19.2 3.6 0.0012 19.2 3.6 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY93079.1 - 0.0025 18.2 18.8 0.0027 18.1 3.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY93079.1 - 0.0049 17.6 2.7 0.0049 17.6 2.7 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 ORY93079.1 - 0.015 15.6 2.3 0.038 14.4 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORY93079.1 - 0.11 13.1 0.2 0.11 13.1 0.2 4.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORY93079.1 - 0.19 11.8 5.6 0.095 12.7 2.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY93079.1 - 0.39 11.0 4.8 1.8 8.9 4.8 2.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon Aminotran_1_2 PF00155.21 ORY93080.1 - 2e-78 264.1 0.0 2.5e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY93080.1 - 1.4e-06 27.1 0.0 2.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY93080.1 - 4e-05 22.7 0.0 0.00025 20.1 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY93080.1 - 0.001 18.5 0.2 0.002 17.5 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Preseq_ALAS PF09029.10 ORY93080.1 - 0.041 14.4 7.6 0.28 11.7 7.6 2.2 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.17 ORY93080.1 - 0.058 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OMPdecase PF00215.24 ORY93080.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Abhydrolase_2 PF02230.16 ORY93081.1 - 2.8e-16 60.0 0.0 3.5e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ORY93081.1 - 0.017 14.8 0.0 0.078 12.6 0.0 2.1 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 ORY93081.1 - 0.02 14.4 0.0 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 ORY93081.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORY93081.1 - 0.036 14.7 0.0 0.049 14.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ORY93081.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_tran_WecB PF03808.13 ORY93081.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Prenylcys_lyase PF07156.14 ORY93082.1 - 1.2e-67 228.6 0.0 1.6e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 ORY93082.1 - 3.7e-16 59.4 0.0 5.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY93082.1 - 1.3e-09 38.1 0.0 2.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY93082.1 - 7.5e-08 32.3 0.2 0.0012 18.6 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY93082.1 - 4.6e-05 22.8 0.0 0.0082 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY93082.1 - 0.026 13.8 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ORY93082.1 - 0.06 12.2 0.1 0.085 11.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 ORY93082.1 - 0.12 13.0 0.1 5.4 7.6 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY93082.1 - 0.16 10.6 0.1 0.28 9.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_1 PF00561.20 ORY93083.1 - 1.7e-35 122.9 0.0 2.5e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY93083.1 - 3.3e-20 73.6 0.0 4.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY93083.1 - 3.9e-15 55.8 0.0 1.8e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ORY93083.1 - 0.0029 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 ORY93083.1 - 0.0038 16.8 0.0 0.6 9.6 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.13 ORY93083.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 ORY93083.1 - 0.029 13.1 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF2920 PF11144.8 ORY93083.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF1057 PF06342.12 ORY93083.1 - 0.22 10.5 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 ORY93084.1 - 6.2e-31 108.0 0.1 2.9e-30 105.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY93084.1 - 1.4e-21 78.2 0.0 1.7e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY93084.1 - 3.1e-15 56.1 0.0 2.2e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY93084.1 - 0.001 17.8 0.0 0.0026 16.5 0.0 1.6 2 0 0 2 2 2 1 Ndr family DUF1057 PF06342.12 ORY93084.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 ORY93084.1 - 0.025 14.7 0.0 0.061 13.5 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein PGAP1 PF07819.13 ORY93084.1 - 0.064 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 ORY93084.1 - 0.074 12.6 0.0 0.58 9.7 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 ORY93084.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase TFR_dimer PF04253.15 ORY93085.1 - 6e-30 103.8 0.1 1.2e-29 102.9 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORY93085.1 - 1.3e-25 90.3 0.0 2.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY93085.1 - 5.7e-10 39.1 0.0 5.2e-09 36.0 0.0 2.5 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.28 ORY93085.1 - 0.0043 16.8 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3328 PF11807.8 ORY93085.1 - 0.052 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Nicastrin PF05450.15 ORY93085.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Nicastrin UPF0014 PF03649.13 ORY93086.1 - 2.3e-42 145.0 12.3 2.6e-42 144.8 12.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) OATP PF03137.20 ORY93086.1 - 0.8 7.9 4.8 1.4 7.1 4.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UPF0014 PF03649.13 ORY93087.1 - 6.2e-13 48.7 0.6 7.3e-13 48.4 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) TMF_TATA_bd PF12325.8 ORY93088.1 - 0.0023 18.1 6.7 0.0023 18.1 6.7 3.7 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding IFT20 PF14931.6 ORY93088.1 - 0.014 15.5 9.9 0.014 15.5 9.9 3.6 1 1 4 5 5 5 0 Intraflagellar transport complex B, subunit 20 LPP PF04728.13 ORY93088.1 - 0.075 13.4 14.1 7.3 7.1 0.3 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF4200 PF13863.6 ORY93088.1 - 0.088 13.2 0.6 0.088 13.2 0.6 3.6 1 1 3 4 4 3 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 ORY93088.1 - 0.12 12.9 34.2 0.32 11.5 16.1 3.5 1 1 3 4 4 4 0 Apg6 coiled-coil region RasGAP_C PF03836.15 ORY93088.1 - 0.27 11.4 19.9 2.4 8.3 0.5 3.2 2 1 1 3 3 3 0 RasGAP C-terminus Uso1_p115_C PF04871.13 ORY93088.1 - 0.37 11.2 29.6 2 8.8 5.3 4.0 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 ORY93088.1 - 0.49 10.4 19.8 2.9 8.0 1.3 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 ORY93088.1 - 0.54 9.7 32.3 2.1 7.7 21.2 2.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 SHE3 PF17078.5 ORY93088.1 - 0.55 9.9 24.9 3.7 7.2 25.4 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 HsbA PF12296.8 ORY93088.1 - 2.2 8.7 10.5 1.8 9.0 2.5 3.3 2 2 1 3 3 3 0 Hydrophobic surface binding protein A DUF948 PF06103.11 ORY93088.1 - 2.5 8.4 14.9 3.5 7.9 0.5 4.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) P4Ha_N PF08336.11 ORY93088.1 - 3.9 7.5 17.9 7.6 6.6 0.1 3.9 3 1 0 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Sulfatase_C PF14707.6 ORY93088.1 - 4.1 8.2 9.5 11 6.8 0.4 3.5 2 1 2 4 4 4 0 C-terminal region of aryl-sulfatase Spc7 PF08317.11 ORY93088.1 - 4.2 6.2 32.3 1.5 7.7 15.8 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein ApoO PF09769.9 ORY93088.1 - 4.2 7.3 8.6 0.64 10.0 0.3 3.0 2 2 1 3 3 3 0 Apolipoprotein O DUF745 PF05335.13 ORY93088.1 - 8.1 6.1 29.0 5.5 6.7 0.4 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF745) PRKG1_interact PF15898.5 ORY93088.1 - 8.5 7.4 31.0 12 6.9 15.1 3.5 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF4201 PF13870.6 ORY93088.1 - 9.8 5.9 30.9 2.2 8.0 4.4 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) Pkinase PF00069.25 ORY93089.1 - 4.2e-18 65.7 0.0 1e-17 64.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 ORY93089.1 - 0.00046 19.1 0.8 0.0012 17.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY93089.1 - 0.01 15.8 0.0 0.054 13.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 ORY93089.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Acyl-CoA_dh_N PF02771.16 ORY93090.1 - 5.7e-29 101.1 0.1 1.2e-28 100.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY93090.1 - 1.3e-28 100.1 0.3 2.2e-28 99.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY93090.1 - 1.8e-20 72.9 0.1 3.1e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY93090.1 - 5.7e-08 33.1 0.3 1.4e-07 31.8 0.3 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MIR PF02815.19 ORY93091.1 - 5.8e-14 52.4 0.4 3e-12 46.8 0.0 2.8 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 ORY93091.1 - 4.1e-05 22.9 0.0 0.0015 17.8 0.0 2.2 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor TAF4 PF05236.14 ORY93092.1 - 0.57 9.9 12.0 0.028 14.2 1.8 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DUF4577 PF15145.6 ORY93092.1 - 4 7.5 7.7 6 6.9 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) DNA_pol_B PF00136.21 ORY93093.1 - 1.8e-83 280.8 0.2 3e-83 280.1 0.0 1.4 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY93093.1 - 6.4e-62 209.6 1.0 1.1e-61 208.8 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY93093.1 - 1.1e-15 57.8 6.8 3.1e-15 56.4 6.8 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_3 PF08408.10 ORY93093.1 - 0.064 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase family B viral insert DNA_pol_B_exo2 PF10108.9 ORY93093.1 - 0.076 12.7 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 ORY93093.1 - 0.69 9.8 4.6 2.4 8.1 4.6 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ACC PF17848.1 ORY93093.1 - 4.5 7.4 5.6 0.98 9.6 0.4 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Thaumatin PF00314.17 ORY93094.1 - 1.8e-49 168.3 16.8 1.1e-48 165.7 16.8 1.8 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORY93094.1 - 0.02 14.2 1.8 4.6 6.4 2.1 2.2 1 1 1 2 2 2 0 Beta-1,3-glucanase Y_phosphatase2 PF03162.13 ORY93095.1 - 2.7e-41 140.9 0.0 3.2e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY93095.1 - 0.0007 19.4 0.0 0.00084 19.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY93095.1 - 0.0092 15.6 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY93095.1 - 0.011 15.8 0.0 0.012 15.6 0.0 1.2 1 1 0 1 1 1 0 Tyrosine phosphatase family GST_N_3 PF13417.6 ORY93097.1 - 6.3e-14 52.1 0.0 1.3e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY93097.1 - 3.4e-08 33.7 0.0 6.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY93097.1 - 6.1e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY93097.1 - 5.6e-07 29.5 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY93097.1 - 2.4e-06 27.7 0.0 5.6e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY93097.1 - 0.0089 16.2 0.0 0.044 14.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.6 ORY93097.1 - 0.02 15.3 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY93097.1 - 0.028 14.2 0.0 0.11 12.3 0.0 2.0 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain Chitin_synth_2 PF03142.15 ORY93098.1 - 1.6e-239 795.9 0.4 2.5e-239 795.3 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY93098.1 - 4.1e-110 369.0 3.1 6.1e-110 368.4 3.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 ORY93098.1 - 4.4e-18 65.2 0.0 1.3e-13 50.8 0.0 3.9 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 ORY93098.1 - 1.9e-14 54.1 0.0 1.4e-13 51.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY93098.1 - 2e-14 54.0 2.7 2e-14 54.0 2.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY93098.1 - 3.6e-08 33.4 0.0 7.9e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY93098.1 - 5.7e-05 22.7 0.0 0.00084 18.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Wzy_C PF04932.15 ORY93098.1 - 0.017 14.8 0.2 2 8.1 0.1 2.5 2 0 0 2 2 2 0 O-Antigen ligase Glyco_tranf_2_5 PF13712.6 ORY93098.1 - 0.033 13.9 0.1 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family ATG16 PF08614.11 ORY93098.1 - 0.4 10.9 3.7 0.9 9.7 3.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RhoGAP PF00620.27 ORY93100.1 - 3.5e-39 134.0 0.4 7.3e-39 133.0 0.4 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY93100.1 - 1.5e-14 53.9 45.3 1.8e-07 31.3 6.5 5.9 5 0 0 5 5 5 4 LIM domain DUF2688 PF10892.8 ORY93100.1 - 3 7.4 6.8 0.47 10.0 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) AAA PF00004.29 ORY93101.1 - 0.0011 19.4 0.2 0.009 16.4 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY93101.1 - 0.0082 16.5 0.2 0.1 13.0 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain PBP1_TM PF14812.6 ORY93101.1 - 4.3 7.8 11.5 0.35 11.3 5.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1604 PF07713.13 ORY93102.1 - 8.6e-40 134.5 2.8 8.6e-40 134.5 2.8 4.7 4 1 1 5 5 5 2 Protein of unknown function (DUF1604) G-patch PF01585.23 ORY93102.1 - 1.6e-06 27.9 1.1 4.5e-06 26.5 0.2 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 ORY93102.1 - 0.2 11.8 0.0 0.2 11.8 0.0 4.2 4 1 0 4 4 4 0 G-patch domain DUF2415 PF10313.9 ORY93103.1 - 1.9e-10 40.5 0.1 9.4e-10 38.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 ORY93103.1 - 2.8e-08 34.3 0.9 0.018 15.9 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93103.1 - 1.2e-07 31.9 0.0 0.006 16.9 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY93103.1 - 0.00023 20.2 0.2 0.0031 16.5 0.0 2.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY93103.1 - 0.041 12.4 0.0 1 7.8 0.0 2.3 1 1 0 2 2 2 0 Cytochrome D1 heme domain DUF3952 PF13130.6 ORY93103.1 - 0.15 12.2 0.1 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) FG-GAP PF01839.23 ORY93103.1 - 0.51 10.5 0.1 0.51 10.5 0.1 2.5 4 0 0 4 4 4 0 FG-GAP repeat zinc_ribbon_6 PF14599.6 ORY93104.1 - 1e-25 89.5 2.3 1e-25 89.5 2.3 4.6 3 2 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 ORY93104.1 - 1.7e-20 73.2 21.5 1.7e-20 73.2 21.5 3.9 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 ORY93104.1 - 4.3e-08 33.4 8.4 4.3e-08 33.4 8.4 5.6 3 2 1 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY93104.1 - 0.0005 20.0 4.8 0.0005 20.0 4.8 4.8 4 1 1 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY93104.1 - 0.0017 18.2 10.8 0.0017 18.2 10.8 6.0 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY93104.1 - 0.0035 17.2 7.3 0.0035 17.2 7.3 6.2 4 3 3 7 7 7 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY93104.1 - 0.019 14.9 12.0 0.019 14.9 12.0 7.0 3 2 1 4 4 4 0 zinc-RING finger domain Tcf25 PF04910.14 ORY93105.1 - 7.7e-102 341.0 0.6 1e-101 340.6 0.6 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 FAM219A PF15260.6 ORY93105.1 - 0.0029 18.0 1.2 0.057 13.8 0.5 2.7 2 0 0 2 2 2 1 Protein family FAM219A Stm1_N PF09598.10 ORY93105.1 - 0.021 15.7 10.3 0.021 15.7 10.3 2.5 3 0 0 3 3 3 0 Stm1 XAP5 PF04921.14 ORY93105.1 - 0.041 13.7 2.7 0.096 12.5 2.7 1.6 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3402 PF11882.8 ORY93105.1 - 0.27 10.3 5.3 0.46 9.5 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) NAM-associated PF14303.6 ORY93105.1 - 2.5 8.8 14.9 6.1 7.5 14.9 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Methyltransf_11 PF08241.12 ORY93106.1 - 3e-23 82.3 0.0 4.5e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY93106.1 - 5.7e-20 71.8 0.0 8.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY93106.1 - 3.8e-18 65.7 0.0 5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY93106.1 - 6e-16 58.7 0.0 7.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93106.1 - 3.8e-12 46.8 0.0 5.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY93106.1 - 7.2e-12 44.9 0.0 1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ORY93106.1 - 4.1e-08 32.9 0.0 7.7e-08 32.0 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORY93106.1 - 9.7e-08 31.7 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 ORY93106.1 - 3.1e-06 26.7 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 ORY93106.1 - 3.7e-05 23.3 0.0 5.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 ORY93106.1 - 0.0029 17.1 0.0 0.004 16.6 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 ORY93106.1 - 0.0057 16.7 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY93106.1 - 0.0065 16.6 0.0 0.0096 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 ORY93106.1 - 0.0087 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 ORY93106.1 - 0.011 15.4 0.0 0.033 14.0 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 ORY93106.1 - 0.052 13.0 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase HTH_Tnp_IS1 PF12759.7 ORY93106.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 InsA C-terminal domain ADH_zinc_N PF00107.26 ORY93106.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PHINT_rpt PF14882.6 ORY93106.1 - 0.16 12.3 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 Phage-integrase repeat unit Methyltransf_18 PF12847.7 ORY93106.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MlrC_C PF07171.12 ORY93106.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 MlrC C-terminus NMO PF03060.15 ORY93107.1 - 2.2e-62 211.4 0.1 2.5e-62 211.2 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY93107.1 - 3.3e-07 29.6 0.0 0.0035 16.4 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain PcrB PF01884.17 ORY93107.1 - 0.085 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 PcrB family eIF-5a PF01287.20 ORY93107.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Alpha-amylase PF00128.24 ORY93108.1 - 5.7e-58 197.1 1.4 2.3e-57 195.1 1.4 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 ORY93108.1 - 0.00058 20.1 0.3 0.0017 18.6 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) RnfC_N PF13375.6 ORY93108.1 - 0.17 11.9 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PfkB PF00294.24 ORY93112.1 - 5.8e-62 209.7 3.2 6.7e-62 209.5 3.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HMA PF00403.26 ORY93113.1 - 2.8e-62 207.1 5.7 1.4e-14 54.2 0.1 4.9 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 ORY93113.1 - 5.5e-45 154.2 2.9 5.5e-45 154.2 2.9 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY93113.1 - 1.7e-41 141.7 3.7 5.9e-41 140.0 3.7 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY93113.1 - 1.3e-05 25.1 2.0 0.00046 20.0 0.4 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY93113.1 - 0.00054 20.4 0.1 0.0013 19.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DHNA PF04038.12 ORY93113.1 - 0.00079 19.9 0.9 9.9 6.7 0.0 3.8 3 0 0 3 3 3 2 Dihydroneopterin aldolase RRM_3 PF08777.11 ORY93113.1 - 0.0069 16.4 0.0 5.3 7.2 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif CT_C_D PF02682.16 ORY93113.1 - 0.075 12.8 0.6 7.8 6.2 0.1 2.9 1 1 1 2 2 2 0 Carboxyltransferase domain, subdomain C and D Fer2_BFD PF04324.15 ORY93113.1 - 0.1 13.0 13.8 6.1 7.3 0.5 6.0 7 0 0 7 7 7 0 BFD-like [2Fe-2S] binding domain HBS1_N PF08938.10 ORY93113.1 - 0.2 12.0 0.5 7.9 6.9 0.0 3.0 3 0 0 3 3 3 0 HBS1 N-terminus DUF1761 PF08570.10 ORY93113.1 - 0.32 11.3 5.0 1 9.6 0.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) C6 PF01681.17 ORY93113.1 - 0.52 10.9 6.1 0.16 12.5 0.8 3.0 3 0 0 3 3 3 0 C6 domain Ribosomal_S9 PF00380.19 ORY93114.1 - 3.9e-29 101.6 0.0 4.4e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RRM_1 PF00076.22 ORY93115.1 - 3.5e-47 158.1 0.0 2.5e-17 62.5 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY93115.1 - 6.7e-05 22.8 0.0 0.00024 21.0 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY93115.1 - 0.00012 21.6 0.0 0.077 12.6 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY93115.1 - 0.00074 19.6 0.0 0.037 14.1 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 ORY93115.1 - 0.0049 16.7 0.0 0.031 14.1 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif SUIM_assoc PF16619.5 ORY93115.1 - 0.019 15.0 6.6 0.041 13.9 6.6 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RRM_3 PF08777.11 ORY93115.1 - 0.028 14.5 0.1 0.08 13.0 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif TFIIA PF03153.13 ORY93115.1 - 0.067 13.2 9.3 0.082 12.9 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 ORY93115.1 - 0.61 9.0 19.4 3.5 6.5 20.6 1.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Spt20 PF12090.8 ORY93115.1 - 3.1 7.4 12.7 5.2 6.6 12.7 1.3 1 0 0 1 1 1 0 Spt20 family CoA_binding PF02629.19 ORY93116.1 - 2.8e-31 108.1 0.6 2.8e-31 108.1 0.6 2.4 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 ORY93116.1 - 6.6e-26 91.0 0.3 1.1e-25 90.3 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ORY93116.1 - 2.5e-10 40.3 0.0 4.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ORY93116.1 - 0.00011 22.7 0.0 0.00029 21.3 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Glyco_trans_1_4 PF13692.6 ORY93116.1 - 0.0035 17.8 0.2 0.87 10.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 PACT_coil_coil PF10495.9 ORY93117.1 - 1.5e-07 31.9 0.3 1.5e-07 31.9 0.3 2.9 2 1 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF4407 PF14362.6 ORY93117.1 - 1.8 7.9 11.5 2.3 7.5 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 ORY93117.1 - 2.1 8.5 12.5 0.63 10.2 3.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 ORY93117.1 - 2.7 8.5 27.9 0.59 10.7 23.7 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region ALMT PF11744.8 ORY93117.1 - 5 5.9 8.3 6.5 5.5 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 ORY93117.1 - 7.6 4.3 11.2 9.8 3.9 11.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pep1_7 PF17232.2 ORY93118.1 - 0.11 13.0 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 Elicitor peptide 1-7 TMEM164 PF14808.6 ORY93119.1 - 1.1e-23 83.8 12.5 1.5e-23 83.5 12.5 1.0 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.10 ORY93119.1 - 1.5e-05 24.6 27.3 1.9e-05 24.3 27.3 1.1 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) Hydrolase_4 PF12146.8 ORY93121.1 - 1.2e-22 80.4 0.0 1.9e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY93121.1 - 2.8e-22 79.6 0.0 4.4e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY93121.1 - 4.4e-22 79.8 0.1 6.5e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY93121.1 - 1.4e-06 28.0 0.0 0.0057 16.2 0.0 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 ORY93121.1 - 1.5e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 ORY93121.1 - 0.00027 21.1 0.3 0.00046 20.4 0.3 1.7 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 ORY93121.1 - 0.00069 19.3 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_8 PF06259.12 ORY93121.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase VirJ PF06057.11 ORY93121.1 - 0.0048 16.8 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 ORY93121.1 - 0.0051 16.7 0.0 1.9 8.2 0.0 3.4 3 1 0 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 ORY93121.1 - 0.0054 15.4 0.0 0.39 9.3 0.0 2.5 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF900 PF05990.12 ORY93121.1 - 0.017 14.7 0.0 0.047 13.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) FSH1 PF03959.13 ORY93121.1 - 0.025 14.2 0.1 0.22 11.1 0.0 2.5 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 ORY93121.1 - 0.028 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Chlorophyllase2 PF12740.7 ORY93121.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 ORY93121.1 - 0.07 12.9 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 ORY93121.1 - 0.09 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) RCC1 PF00415.18 ORY93122.1 - 1.8e-80 265.4 5.5 5.7e-12 46.1 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY93122.1 - 3.7e-46 154.1 27.3 7.4e-08 32.0 0.2 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 ORY93122.1 - 0.0074 16.0 0.1 4.2 7.0 0.0 3.7 5 0 0 5 5 5 2 TUP1-like enhancer of split Sacchrp_dh_NADP PF03435.18 ORY93123.1 - 1.2e-18 67.7 0.0 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORY93123.1 - 2.1e-05 24.5 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY93123.1 - 3.6e-05 23.3 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY93123.1 - 0.00023 20.8 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ORY93123.1 - 0.0018 17.3 0.1 0.0027 16.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY93123.1 - 0.0029 17.1 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY93123.1 - 0.0029 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY93123.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ORY93123.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY93124.1 - 4.9e-19 68.9 0.1 8.2e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORY93124.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY93124.1 - 0.00058 19.5 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY93124.1 - 0.0024 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY93124.1 - 0.0036 16.8 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY93124.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY93124.1 - 0.074 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PAP2 PF01569.21 ORY93125.1 - 1.4e-29 102.6 3.4 2.2e-29 102.0 0.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF5510 PF17629.2 ORY93125.1 - 0.00014 21.7 2.1 0.00053 19.9 0.0 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5510) Ytca PF17090.5 ORY93125.1 - 0.32 11.5 4.1 5.1 7.7 1.3 2.7 2 0 0 2 2 2 0 Uncharacterised protein family Tmemb_185A PF10269.9 ORY93126.1 - 4.1e-18 66.0 20.6 6.2e-07 29.4 2.0 3.2 2 1 0 3 3 3 3 Transmembrane Fragile-X-F protein ATG22 PF11700.8 ORY93126.1 - 0.00011 21.0 0.1 0.00011 21.0 0.1 1.8 1 1 0 2 2 2 1 Vacuole effluxer Atg22 like PBP1_TM PF14812.6 ORY93126.1 - 0.00021 21.6 1.5 0.00051 20.4 1.5 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Orf78 PF06024.12 ORY93126.1 - 0.0033 17.7 7.3 0.32 11.3 0.0 3.9 4 0 0 4 4 4 2 Orf78 (ac78) TMEM208_SND2 PF05620.11 ORY93126.1 - 0.0038 17.0 0.0 0.0038 17.0 0.0 3.4 2 2 1 3 3 3 1 SRP-independent targeting protein 2/TMEM208 DUF2721 PF11026.8 ORY93126.1 - 0.007 16.2 0.1 0.007 16.2 0.1 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF2721) DUF2615 PF11027.8 ORY93126.1 - 0.068 13.3 0.9 6.4 7.0 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2615) Tmemb_9 PF05434.11 ORY93126.1 - 0.23 11.4 0.4 0.76 9.7 0.0 2.1 2 1 0 2 2 2 0 TMEM9 RabGAP-TBC PF00566.18 ORY93127.1 - 1.3e-45 155.7 1.9 2.6e-45 154.7 1.9 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 ORY93127.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Rab-binding domain (RBD) YqeY PF09424.10 ORY93128.1 - 1.3e-36 125.8 8.3 1.6e-36 125.6 8.3 1.1 1 0 0 1 1 1 1 Yqey-like protein Herpes_BBRF1 PF04793.12 ORY93128.1 - 0.014 14.4 0.7 0.017 14.1 0.7 1.1 1 0 0 1 1 1 0 BRRF1-like protein Fanconi_A_N PF15865.5 ORY93128.1 - 0.021 14.2 0.9 0.024 14.0 0.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus DUF4441 PF14536.6 ORY93128.1 - 0.03 14.5 0.0 0.059 13.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) RGI1 PF10843.8 ORY93128.1 - 0.042 13.5 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Respiratory growth induced protein 1 Pkinase PF00069.25 ORY93129.1 - 3.8e-68 229.7 0.0 5.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93129.1 - 9.1e-32 110.3 0.0 1.4e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY93129.1 - 1.9e-05 23.8 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY93129.1 - 4.8e-05 22.8 0.1 0.00016 21.1 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY93129.1 - 0.00039 20.4 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY93129.1 - 0.0029 17.0 0.0 0.14 11.5 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 ORY93129.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY93129.1 - 0.031 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ABC_tran PF00005.27 ORY93130.1 - 3.3e-44 150.7 0.0 9.6e-21 74.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY93130.1 - 2.7e-20 72.2 3.8 2.7e-20 72.2 3.8 2.9 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 ORY93130.1 - 8.9e-19 68.4 3.7 0.00016 21.6 0.2 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY93130.1 - 1.4e-08 34.4 0.1 0.0046 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 ORY93130.1 - 2.8e-08 33.5 0.3 0.054 12.9 0.2 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 ORY93130.1 - 7.1e-07 29.4 0.4 0.14 12.2 0.0 4.2 2 1 1 3 3 3 2 Dynamin family AAA_15 PF13175.6 ORY93130.1 - 2e-06 27.8 4.9 0.093 12.4 0.0 4.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 ORY93130.1 - 2.3e-06 27.9 0.0 0.012 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY93130.1 - 2.8e-06 27.4 0.6 0.043 13.7 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 ORY93130.1 - 5.6e-06 26.6 0.0 0.061 13.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 ORY93130.1 - 6.2e-06 26.9 5.9 0.052 14.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 ORY93130.1 - 1e-05 25.4 0.2 0.22 11.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY93130.1 - 1.2e-05 25.8 0.0 0.16 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY93130.1 - 1.9e-05 24.7 0.0 0.083 13.0 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY93130.1 - 2.2e-05 25.0 0.0 0.3 11.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 ORY93130.1 - 2.5e-05 24.6 0.0 0.25 11.6 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_27 PF13514.6 ORY93130.1 - 5.1e-05 23.0 0.0 0.18 11.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 ORY93130.1 - 8.9e-05 22.5 0.0 0.63 9.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 ORY93130.1 - 0.00031 20.4 0.0 0.59 9.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 ORY93130.1 - 0.00072 19.6 0.0 4.2 7.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 ORY93130.1 - 0.0012 18.8 0.0 2.7 8.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY93130.1 - 0.0012 19.2 0.2 2.2 8.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase DUF87 PF01935.17 ORY93130.1 - 0.0013 18.9 0.8 1.2 9.2 0.0 3.1 3 1 0 3 3 2 1 Helicase HerA, central domain AAA_17 PF13207.6 ORY93130.1 - 0.0014 19.1 5.3 0.016 15.7 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_30 PF13604.6 ORY93130.1 - 0.0036 17.1 0.0 1.1 8.9 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA PF00004.29 ORY93130.1 - 0.0061 17.0 0.0 1 9.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 ORY93130.1 - 0.0069 16.4 0.4 1.8 8.5 0.0 3.2 2 1 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE VirE PF05272.11 ORY93130.1 - 0.0084 15.9 0.1 1.2 8.8 0.0 2.7 3 0 0 3 3 3 1 Virulence-associated protein E SRP54 PF00448.22 ORY93130.1 - 0.0094 15.6 0.6 3.4 7.3 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 ORY93130.1 - 0.01 15.6 0.1 3.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MukB PF04310.12 ORY93130.1 - 0.012 15.5 0.0 3.1 7.5 0.0 2.8 2 0 0 2 2 2 0 MukB N-terminal MeaB PF03308.16 ORY93130.1 - 0.032 13.2 0.0 8.1 5.3 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pox_A32 PF04665.12 ORY93130.1 - 0.039 13.4 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 ORY93130.1 - 0.04 13.2 0.4 3.5 6.8 0.0 2.5 3 0 0 3 3 2 0 Septin SbcCD_C PF13558.6 ORY93130.1 - 0.046 14.0 0.0 2.2 8.6 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 ORY93130.1 - 0.049 13.0 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 ORY93130.1 - 0.052 13.8 0.0 7.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORY93130.1 - 0.074 12.6 0.0 1.9 8.0 0.0 2.5 3 0 0 3 3 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 ORY93130.1 - 0.079 12.1 0.0 5.9 6.0 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Ploopntkinase3 PF18751.1 ORY93130.1 - 0.083 12.8 0.9 5.7 6.8 0.0 2.9 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 ORY93130.1 - 0.089 12.4 0.1 8.2 6.0 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 ORY93130.1 - 0.11 12.4 0.0 3.6 7.5 0.0 2.8 3 0 0 3 3 2 0 NTPase PduV-EutP PF10662.9 ORY93130.1 - 0.12 12.1 0.1 6.4 6.5 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 ORY93130.1 - 0.12 11.5 0.7 15 4.6 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit SH3BGR PF04908.15 ORY93131.1 - 1.4e-13 50.8 0.0 1.4e-13 50.8 0.0 3.7 3 1 1 4 4 4 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 ORY93131.1 - 0.00062 19.9 0.3 0.0042 17.3 0.0 2.7 2 0 0 2 2 2 1 Glutaredoxin ERCC4 PF02732.15 ORY93132.1 - 4.9e-22 78.8 0.1 9.8e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 ERCC4 domain WD40 PF00400.32 ORY93133.1 - 0.0001 23.0 0.2 0.99 10.4 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93133.1 - 0.0032 17.7 0.0 1.1 9.6 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 ORY93133.1 - 0.12 12.4 0.0 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-C3HC4 PF00097.25 ORY93134.1 - 7.8e-08 32.1 13.5 1.3e-07 31.3 13.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY93134.1 - 9.7e-06 25.3 9.7 1.6e-05 24.7 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY93134.1 - 1.8e-05 25.0 14.5 3.3e-05 24.1 14.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY93134.1 - 8e-05 22.6 10.2 8e-05 22.6 10.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY93134.1 - 9.9e-05 22.1 13.2 0.00025 20.8 13.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY93134.1 - 0.00033 20.6 11.7 0.00063 19.6 11.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY93134.1 - 0.00033 20.7 9.9 0.00088 19.4 9.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING PAM2 PF07145.15 ORY93134.1 - 0.0056 16.3 0.6 0.021 14.5 0.6 2.1 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Prok-RING_4 PF14447.6 ORY93134.1 - 0.021 14.7 9.9 0.051 13.4 10.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Plant_tran PF04827.14 ORY93134.1 - 0.035 13.7 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Plant transposon protein zf-ANAPC11 PF12861.7 ORY93134.1 - 0.06 13.4 5.6 0.11 12.6 5.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cu_amine_oxidN3 PF02728.16 ORY93134.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain zf-rbx1 PF12678.7 ORY93134.1 - 0.87 9.9 12.3 2.4 8.5 12.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain Glyco_hydro_9 PF00759.19 ORY93135.1 - 1.6e-93 314.4 16.6 1.6e-93 314.4 16.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 Antirestrict PF03230.13 ORY93135.1 - 0.028 14.5 0.6 0.21 11.6 0.0 2.7 3 0 0 3 3 3 0 Antirestriction protein WD40 PF00400.32 ORY93136.1 - 2.7e-27 94.5 21.0 1.7e-07 31.8 0.1 7.2 8 0 0 8 8 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93136.1 - 1.3e-24 86.3 2.1 1.2e-05 25.5 0.0 6.1 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY93136.1 - 2.2e-10 40.7 1.2 4.2e-06 26.8 0.3 4.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY93136.1 - 4.8e-06 25.5 1.4 0.017 13.8 0.2 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY93136.1 - 0.00016 21.1 0.1 1.1 8.6 0.0 3.3 3 2 0 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 ORY93136.1 - 0.0016 17.1 0.0 0.044 12.3 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain IKI3 PF04762.12 ORY93136.1 - 0.0019 16.3 0.1 0.3 9.0 0.0 2.5 1 1 2 3 3 3 2 IKI3 family PD40 PF07676.12 ORY93136.1 - 0.01 15.8 0.1 0.27 11.2 0.0 3.2 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 ORY93136.1 - 0.063 12.3 0.3 0.17 10.9 0.1 1.7 2 1 0 2 2 2 0 Coatomer WD associated region CNH PF00780.22 ORY93136.1 - 0.097 12.3 0.0 0.78 9.3 0.0 2.0 2 0 0 2 2 2 0 CNH domain DUF2415 PF10313.9 ORY93136.1 - 0.15 12.0 0.0 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Frtz PF11768.8 ORY93136.1 - 0.22 9.8 0.0 0.44 8.8 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Kri1_C PF12936.7 ORY93137.1 - 1.2e-28 99.1 4.4 1.2e-28 99.1 4.4 4.1 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 ORY93137.1 - 1.3e-23 83.5 8.9 1.3e-23 83.5 8.9 6.8 6 2 1 7 7 7 1 KRI1-like family Pkinase PF00069.25 ORY93138.1 - 3e-49 167.8 0.0 3.9e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93138.1 - 2e-28 99.4 0.0 2.7e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY93138.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY93138.1 - 0.0061 15.9 0.1 0.05 12.9 0.0 2.4 3 1 0 3 3 3 1 Kinase-like APH PF01636.23 ORY93138.1 - 0.03 14.2 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY93138.1 - 0.049 12.7 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 ORY93138.1 - 0.15 11.6 0.0 0.81 9.2 0.0 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase TB2_DP1_HVA22 PF03134.19 ORY93139.1 - 1.2e-30 105.3 5.9 1.2e-30 105.3 5.9 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Homeobox_KN PF05920.11 ORY93141.1 - 5.3e-19 67.9 1.3 1.2e-18 66.8 1.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY93141.1 - 5.9e-06 26.0 0.6 1.5e-05 24.7 0.6 1.8 1 0 0 1 1 1 1 Homeodomain CBM_21 PF03370.13 ORY93142.1 - 8e-29 100.1 0.1 1.4e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY93142.1 - 7.4e-10 39.3 1.5 1.6e-09 38.2 0.7 1.9 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) zf-C2H2 PF00096.26 ORY93143.1 - 5.8e-05 23.3 0.6 0.091 13.3 0.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY93143.1 - 0.00014 22.4 1.0 0.074 13.9 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY93143.1 - 0.0074 16.5 0.4 0.3 11.4 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY93143.1 - 0.029 14.7 1.3 0.52 10.6 1.5 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 ORY93143.1 - 0.045 14.0 0.9 0.13 12.5 0.9 1.7 1 1 0 1 1 1 0 LIM domain PyrI_C PF02748.15 ORY93143.1 - 3.2 7.7 4.1 7 6.6 0.4 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain NT5C PF06941.12 ORY93145.1 - 3e-09 37.0 2.0 3.5e-09 36.8 0.2 2.0 3 0 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 ORY93145.1 - 1.2e-05 25.4 0.0 4.8e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 ORY93145.1 - 0.004 16.9 0.2 0.0091 15.8 0.2 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 ORY93145.1 - 0.0086 16.4 0.0 0.042 14.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY93145.1 - 0.015 15.7 0.4 0.051 14.0 0.4 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMP-TENI PF02581.17 ORY93145.1 - 0.017 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase SDA1 PF05285.12 ORY93145.1 - 4 6.8 15.6 5.6 6.3 15.6 1.2 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 ORY93146.1 - 0.084 12.2 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 ORY93147.1 - 7.9e-48 163.1 0.4 2.1e-47 161.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93147.1 - 1e-21 77.4 0.7 1.4e-21 76.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 ORY93147.1 - 1.7e-13 50.1 0.1 3.7e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORY93147.1 - 3.1e-09 36.6 0.0 5.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SUIM_assoc PF16619.5 ORY93147.1 - 0.00061 19.8 6.7 0.00061 19.8 6.7 4.6 5 0 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Haspin_kinase PF12330.8 ORY93147.1 - 0.038 12.9 0.1 0.038 12.9 0.1 2.2 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 ORY93147.1 - 0.044 13.7 0.3 0.044 13.7 0.3 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY93147.1 - 0.14 11.5 1.2 0.2 11.0 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY93147.1 - 0.18 11.4 0.1 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Utp14 PF04615.13 ORY93150.1 - 4.5e-192 640.6 96.7 4.5e-192 640.6 96.7 2.2 1 1 1 2 2 2 1 Utp14 protein RasGAP PF00616.19 ORY93151.1 - 4e-25 88.7 0.0 1e-15 58.1 0.0 2.8 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 ORY93151.1 - 8.7e-21 74.5 0.4 3e-20 72.8 0.4 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 ORY93151.1 - 2.5e-05 24.3 0.0 0.00011 22.1 0.0 2.2 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Cnd1 PF12717.7 ORY93151.1 - 3.7e-05 23.8 0.3 0.00028 20.9 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY93151.1 - 4.1e-05 23.5 5.1 0.0065 16.6 0.1 4.6 3 0 0 3 3 3 1 HEAT repeat CRAL_TRIO PF00650.20 ORY93151.1 - 0.0012 18.6 0.4 0.0045 16.7 0.4 1.9 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT_2 PF13646.6 ORY93151.1 - 2.1 8.8 9.8 0.36 11.2 0.0 4.9 8 0 0 8 8 8 0 HEAT repeats PRMT5_TIM PF17285.2 ORY93152.1 - 0.0069 15.6 0.0 0.84 8.8 0.0 2.4 2 0 0 2 2 2 2 PRMT5 TIM barrel domain Glyco_hydro_47 PF01532.20 ORY93153.1 - 6.9e-148 493.3 0.0 8e-148 493.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AMP-binding PF00501.28 ORY93154.1 - 7.5e-42 143.4 0.1 9.1e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DCP2 PF05026.13 ORY93155.1 - 5.1e-20 71.6 5.0 1.1e-17 64.1 1.6 2.4 1 1 1 2 2 2 2 Dcp2, box A domain NUDIX PF00293.28 ORY93155.1 - 3.1e-18 66.1 0.0 5.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ADH_N PF08240.12 ORY93156.1 - 1.2e-18 67.0 4.2 2.1e-18 66.2 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY93156.1 - 6.1e-11 42.4 0.0 1.8e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY93156.1 - 3.9e-05 23.1 0.0 6.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY93156.1 - 0.001 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY93156.1 - 0.0092 16.2 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 ORY93156.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_23 PF13489.6 ORY93156.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Fer4_6 PF12837.7 ORY93156.1 - 5.9 7.1 6.3 0.9 9.7 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Catalase PF00199.19 ORY93157.1 - 4.5e-205 681.1 0.3 5.5e-205 680.8 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY93157.1 - 3.7e-24 84.7 0.2 7.2e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive FAD_binding_1 PF00667.20 ORY93159.1 - 2e-54 184.5 0.0 2.8e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY93159.1 - 7.4e-35 120.3 0.4 1.9e-34 118.9 0.4 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY93159.1 - 7.1e-19 68.5 0.0 2.6e-18 66.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PX PF00787.24 ORY93160.1 - 8.5e-11 41.8 0.0 4.7e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY93160.1 - 0.00086 18.9 7.6 0.00086 18.9 7.6 1.6 1 1 0 1 1 1 1 Vps5 C terminal like Stimulus_sens_1 PF13756.6 ORY93160.1 - 0.075 13.6 0.1 0.075 13.6 0.1 2.3 3 0 0 3 3 3 0 Stimulus-sensing domain Snf7 PF03357.21 ORY93161.1 - 8.7e-44 149.2 23.6 8.7e-44 149.2 23.6 1.4 2 0 0 2 2 2 1 Snf7 TPR_MLP1_2 PF07926.12 ORY93161.1 - 0.34 11.0 10.2 0.56 10.3 9.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 ORY93161.1 - 0.36 10.3 7.1 0.51 9.9 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DnaJ-X PF14308.6 ORY93161.1 - 1.6 8.1 12.2 0.082 12.3 6.1 1.8 1 1 1 2 2 2 0 X-domain of DnaJ-containing YlqD PF11068.8 ORY93161.1 - 2.8 8.3 19.7 4.4 7.7 9.8 2.2 1 1 1 2 2 2 0 YlqD protein Glucan_synthase PF02364.15 ORY93162.1 - 0 1250.4 0.0 0 1249.5 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORY93162.1 - 2.1e-34 118.6 2.0 1.9e-33 115.5 2.0 2.3 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ribosomal_S26e PF01283.19 ORY93163.1 - 1.5e-41 141.2 9.3 1.6e-41 141.1 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Glyco_hydro_38N PF01074.22 ORY93164.1 - 5.4e-88 295.1 0.5 5.4e-88 295.1 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ORY93164.1 - 1.2e-58 198.7 0.1 2e-58 198.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ORY93164.1 - 1.8e-21 76.1 0.0 3.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ORY93164.1 - 1.6e-13 50.6 0.0 3.5e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 ORY93164.1 - 0.055 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Mt_ATP-synt_D PF05873.12 ORY93165.1 - 1.1e-24 87.0 3.3 1.4e-24 86.7 3.3 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) 120_Rick_ant PF12574.8 ORY93165.1 - 0.00084 18.6 0.3 0.0012 18.1 0.3 1.4 1 0 0 1 1 1 1 120 KDa Rickettsia surface antigen BLOC1_2 PF10046.9 ORY93165.1 - 0.0039 17.4 3.8 0.0053 17.0 1.8 2.1 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 ORY93165.1 - 0.023 14.8 0.9 0.037 14.1 0.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 ORY93165.1 - 0.025 12.6 2.0 0.027 12.5 2.0 1.0 1 0 0 1 1 1 0 Prominin DUF327 PF03885.13 ORY93165.1 - 0.026 14.5 1.7 0.33 10.9 1.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF327) SesA PF17107.5 ORY93165.1 - 0.034 14.3 4.4 0.064 13.5 0.5 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GGACT PF06094.12 ORY93165.1 - 0.08 13.5 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like RPW8 PF05659.11 ORY93165.1 - 0.11 12.1 2.1 0.22 11.2 0.8 2.0 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMPIT PF07851.13 ORY93165.1 - 0.15 11.3 1.2 0.18 11.0 0.9 1.3 1 1 0 1 1 1 0 TMPIT-like protein DUF4600 PF15372.6 ORY93165.1 - 0.26 11.7 3.3 7.4 7.0 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) NPV_P10 PF05531.12 ORY93165.1 - 1.5 9.3 6.5 3.6 8.1 3.5 2.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 ORY93165.1 - 2.6 8.1 8.4 12 6.0 1.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 ORY93166.1 - 6e-18 64.7 3.8 7.1e-18 64.5 3.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit Glyco_hyd_65N_2 PF14498.6 ORY93166.1 - 0.0045 16.9 0.4 0.0055 16.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF413 PF04219.12 ORY93166.1 - 0.019 15.0 0.4 0.036 14.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF DUF4686 PF15742.5 ORY93166.1 - 0.082 12.0 7.3 0.33 10.0 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) GAD PF02938.14 ORY93166.1 - 0.092 13.0 0.0 0.76 10.0 0.0 2.1 1 1 1 2 2 2 0 GAD domain Phe_tRNA-synt_N PF02912.18 ORY93166.1 - 0.2 11.6 2.6 2 8.4 0.1 2.3 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Prefoldin PF02996.17 ORY93166.1 - 0.81 9.6 6.3 2.4 8.1 0.6 2.3 1 1 2 3 3 3 0 Prefoldin subunit Aminotran_5 PF00266.19 ORY93167.1 - 1.1e-09 37.8 0.0 1.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 ORY93167.1 - 0.24 10.0 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III Zn_clus PF00172.18 ORY93168.1 - 2.3e-10 40.4 13.1 3.9e-10 39.7 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 ORY93168.1 - 1.3 8.6 28.2 1.6 8.3 19.8 2.5 2 0 0 2 2 2 0 Spt20 family MMM1 PF10296.9 ORY93169.1 - 9.7e-70 235.2 0.2 2.5e-69 233.9 0.2 1.6 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ThrE PF06738.12 ORY93170.1 - 4e-50 170.4 25.8 1.6e-46 158.6 4.6 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY93170.1 - 9.1e-09 35.5 11.9 9.1e-09 35.5 11.9 2.9 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE DnaJ PF00226.31 ORY93171.1 - 2.8e-06 27.4 0.1 4.8e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 ORY93171.1 - 0.00071 19.6 0.0 0.00073 19.6 0.0 1.1 1 0 0 1 1 1 1 Pam16 DUF5353 PF17304.2 ORY93171.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5353) FxsA PF04186.13 ORY93171.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Proteasome PF00227.26 ORY93172.1 - 1.2e-53 181.5 0.0 1.4e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY93172.1 - 8.3e-14 51.0 0.0 1.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cation_ATPase_C PF00689.21 ORY93173.1 - 1.2e-45 155.4 16.0 2e-45 154.8 10.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY93173.1 - 1.9e-40 138.3 1.1 1.9e-40 138.3 1.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY93173.1 - 3.2e-24 84.8 0.0 7.1e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY93173.1 - 5.6e-17 62.7 0.5 1.3e-16 61.5 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY93173.1 - 7.1e-12 44.9 0.0 2.4e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY93173.1 - 0.001 18.9 0.3 0.0021 17.8 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 ORY93174.1 - 4.3e-28 98.1 0.2 2e-27 95.9 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 ORY93174.1 - 1.8e-07 31.0 0.1 3.3e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORY93174.1 - 3.2e-07 30.6 0.0 1.2e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY93174.1 - 0.048 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Pox_Ag35 PF03286.14 ORY93174.1 - 0.052 13.3 7.7 0.12 12.1 7.7 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 ORY93174.1 - 0.098 12.5 5.1 0.22 11.3 5.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3c_N PF05470.12 ORY93174.1 - 2.1 6.6 9.4 3.3 5.9 9.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM60A PF15396.6 ORY93174.1 - 2.4 8.1 6.4 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF4637 PF15470.6 ORY93174.1 - 2.5 7.8 16.2 0.034 13.9 8.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Sporozoite_P67 PF05642.11 ORY93174.1 - 3.9 5.5 6.7 7.5 4.5 6.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 ORY93174.1 - 5.8 4.9 15.7 9 4.2 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 ORY93175.1 - 0.75 9.7 6.2 1.2 9.1 0.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain LAT PF15234.6 ORY93175.1 - 2.3 7.9 13.5 3.3 7.4 13.5 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells zf-C2H2 PF00096.26 ORY93176.1 - 6.4e-10 38.9 5.9 0.00053 20.3 1.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY93176.1 - 2.5e-05 24.8 7.4 0.0053 17.4 0.2 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY93176.1 - 5.2e-05 23.7 8.8 0.019 15.8 0.9 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY93176.1 - 8.3e-05 22.8 2.3 8.3e-05 22.8 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY93176.1 - 0.0078 16.5 2.2 0.01 16.1 0.4 2.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY93176.1 - 0.016 15.6 1.3 0.076 13.4 0.5 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zap1_zf2 PF18217.1 ORY93176.1 - 0.074 13.1 3.2 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 GCOM2 PF15328.6 ORY93176.1 - 0.42 10.9 8.0 0.2 12.0 3.6 2.3 2 1 1 3 3 3 0 Putative GRINL1B complex locus protein 2 zf-C2H2_6 PF13912.6 ORY93176.1 - 0.45 10.6 5.8 0.12 12.4 0.6 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY93176.1 - 1 9.7 5.4 1.3e+02 3.0 6.5 3.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORY93176.1 - 5.4 7.1 6.3 61 3.7 6.3 2.5 1 1 0 1 1 1 0 BED zinc finger Ank_2 PF12796.7 ORY93179.1 - 4.4e-22 78.5 0.0 7.6e-14 52.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY93179.1 - 1.5e-18 64.9 1.1 4.5e-05 23.5 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 ORY93179.1 - 1.3e-15 57.6 0.2 1.7e-05 25.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY93179.1 - 8.3e-14 51.3 1.8 0.014 15.8 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 ORY93179.1 - 4.8e-12 45.9 4.3 2.2e-05 24.6 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Utp14 PF04615.13 ORY93179.1 - 0.00071 18.3 5.1 0.0011 17.7 5.1 1.2 1 0 0 1 1 1 1 Utp14 protein Pkinase PF00069.25 ORY93180.1 - 2.1e-66 224.0 0.0 3.5e-66 223.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93180.1 - 2.2e-41 141.9 0.0 3.7e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY93180.1 - 1.9e-06 27.4 0.1 9.3e-05 21.9 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 ORY93180.1 - 1.4e-05 24.5 0.4 3.8e-05 23.1 0.4 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3848 PF12959.7 ORY93180.1 - 0.014 15.5 0.6 0.39 10.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) APH PF01636.23 ORY93180.1 - 0.026 14.4 0.5 0.35 10.7 0.5 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CotH PF08757.11 ORY93181.1 - 5.1e-36 124.8 3.4 7.3e-36 124.3 3.4 1.2 1 0 0 1 1 1 1 CotH kinase protein RRM_1 PF00076.22 ORY93182.1 - 2.4e-34 117.0 0.1 2.7e-16 59.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY93182.1 - 6.6e-10 39.0 0.2 0.00025 21.1 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 ORY93182.1 - 0.029 14.4 0.1 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif FAD-oxidase_C PF02913.19 ORY93183.1 - 4.9e-61 206.5 0.0 1.1e-60 205.3 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY93183.1 - 4.8e-38 130.0 0.3 9.5e-38 129.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Relaxase PF03432.14 ORY93183.1 - 0.019 14.6 0.0 0.32 10.6 0.0 2.6 2 1 1 3 3 3 0 Relaxase/Mobilisation nuclease domain Peptidase_M28 PF04389.17 ORY93184.1 - 6.8e-39 133.6 0.0 1.2e-38 132.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 ORY93184.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Nicastrin PriCT_2 PF08707.11 ORY93184.1 - 0.073 13.5 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) DUF4396 PF14342.6 ORY93185.1 - 3.6e-43 147.3 5.7 4.3e-43 147.0 5.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Polysacc_synt_C PF14667.6 ORY93185.1 - 0.21 11.6 3.2 1.2 9.2 3.5 1.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain UBA PF00627.31 ORY93186.1 - 1e-27 95.6 5.5 2.1e-15 56.3 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 ORY93186.1 - 9.5e-23 79.7 9.0 9.5e-23 79.7 9.0 2.6 3 0 0 3 3 1 1 XPC-binding domain ubiquitin PF00240.23 ORY93186.1 - 2.4e-22 78.4 1.3 5.8e-22 77.2 1.3 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY93186.1 - 4.3e-08 32.9 2.2 1.3e-07 31.4 2.2 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 ORY93186.1 - 0.00088 18.9 0.0 0.0083 15.8 0.0 2.4 2 0 0 2 2 2 1 CUE domain Rad60-SLD_2 PF13881.6 ORY93186.1 - 0.0027 17.8 1.4 0.0027 17.8 1.4 2.5 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 ORY93186.1 - 0.0028 17.4 0.0 3.6 7.5 0.0 2.8 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain AAT PF03417.16 ORY93186.1 - 0.031 14.0 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase WIYLD PF10440.9 ORY93186.1 - 0.051 13.4 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain RskA PF10099.9 ORY93186.1 - 0.17 12.1 19.4 0.021 15.1 6.2 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF737 PF05300.11 ORY93186.1 - 0.37 11.1 21.2 0.35 11.2 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) BAT2_N PF07001.11 ORY93186.1 - 0.66 10.4 26.3 0.14 12.6 6.3 2.2 2 0 0 2 2 2 0 BAT2 N-terminus NAP PF00956.18 ORY93186.1 - 0.78 8.9 13.7 0.033 13.4 5.5 2.1 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) IHABP4_N PF16174.5 ORY93186.1 - 2.3 8.8 21.9 7.1 7.2 7.9 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Connexin PF00029.19 ORY93186.1 - 3.1 7.5 5.7 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Connexin TCP PF03634.13 ORY93186.1 - 3.6 8.1 13.5 2 8.9 3.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor FAM110_C PF14160.6 ORY93186.1 - 5.7 8.0 8.6 12 7.0 1.8 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus Tim54 PF11711.8 ORY93186.1 - 6 5.5 16.2 3.8 6.2 4.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CDK2AP PF09806.9 ORY93186.1 - 6.3 6.8 19.3 7.7 6.5 2.3 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Podoplanin PF05808.11 ORY93186.1 - 9.4 6.3 8.0 2.3 8.3 1.9 2.2 2 0 0 2 2 2 0 Podoplanin DUF2721 PF11026.8 ORY93187.1 - 0.042 13.8 0.6 0.068 13.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Fungal_trans PF04082.18 ORY93188.1 - 2.7e-23 82.4 1.9 2.7e-23 82.4 1.9 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain RskA PF10099.9 ORY93188.1 - 0.0048 17.2 10.1 0.0048 17.2 10.1 2.5 2 0 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 ORY93188.1 - 0.42 10.6 54.6 1.6 8.6 38.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Chitin_synth_2 PF03142.15 ORY93189.1 - 3.2e-243 808.1 0.8 4.4e-243 807.7 0.8 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY93189.1 - 3.3e-11 43.5 4.9 3.3e-11 43.5 4.9 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY93189.1 - 3.7e-10 40.1 0.0 9e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Sin_N PF04801.13 ORY93190.1 - 2.2e-52 178.7 2.2 2.8e-52 178.4 2.2 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region zf-A20 PF01754.16 ORY93191.1 - 2.8e-10 39.9 8.9 6.3e-10 38.8 8.9 1.6 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 ORY93191.1 - 2e-06 27.9 9.6 2e-06 27.9 9.6 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger Mitofilin PF09731.9 ORY93191.1 - 0.26 10.1 10.2 0.3 9.9 10.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hamartin PF04388.12 ORY93191.1 - 0.29 9.8 9.9 0.32 9.6 9.9 1.0 1 0 0 1 1 1 0 Hamartin protein MSP1_C PF07462.11 ORY93191.1 - 0.4 9.3 4.2 0.44 9.2 4.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dicty_REP PF05086.12 ORY93191.1 - 1.4 6.8 11.1 1.7 6.6 11.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.11 ORY93191.1 - 3.3 6.1 7.5 3.7 5.9 7.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 MAP65_ASE1 PF03999.12 ORY93191.1 - 5.4 5.6 11.0 7 5.2 11.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Cyclin PF08613.11 ORY93192.1 - 1.6e-13 51.4 0.0 3.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY93192.1 - 1.2e-05 25.1 0.1 2.2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain V-ATPase_H_N PF03224.14 ORY93193.1 - 1e-82 278.0 1.6 1.7e-82 277.3 0.8 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORY93193.1 - 1.2e-42 144.7 2.0 2.3e-41 140.6 0.2 2.9 2 1 1 3 3 3 1 V-ATPase subunit H Arm PF00514.23 ORY93193.1 - 0.00019 21.3 0.0 3.3 7.9 0.0 4.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY93193.1 - 0.0062 16.9 0.7 1.1 9.7 0.0 3.2 4 0 0 4 4 4 1 HEAT repeats LemA PF04011.12 ORY93193.1 - 0.04 13.8 0.2 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 LemA family T6SS_HCP PF05638.12 ORY93193.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system effector, Hcp Terminase_2 PF03592.16 ORY93193.1 - 0.25 11.8 1.9 14 6.1 0.1 3.2 3 0 0 3 3 3 0 Terminase small subunit RicinB_lectin_2 PF14200.6 ORY93194.1 - 5.1e-15 56.0 0.7 2.7e-06 28.0 0.0 2.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ORY93194.1 - 6.5e-11 42.6 0.1 3.5e-10 40.2 0.1 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain ORMDL PF04061.14 ORY93195.1 - 4.1e-54 182.1 6.3 4.8e-54 181.8 6.3 1.0 1 0 0 1 1 1 1 ORMDL family Peptidase_M17 PF00883.21 ORY93196.1 - 2.5e-120 401.5 0.1 3.6e-120 400.9 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ORY93196.1 - 1e-14 54.5 2.3 1.9e-14 53.6 2.3 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Septin PF00735.18 ORY93197.1 - 6.8e-58 196.2 0.4 1.4e-41 142.6 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 ORY93197.1 - 9.2e-08 32.2 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY93197.1 - 0.00018 21.1 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY93197.1 - 0.00036 20.5 0.5 0.021 14.7 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 ORY93197.1 - 0.0025 17.6 0.5 0.95 9.2 0.1 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein CDC45 PF02724.14 ORY93197.1 - 0.0031 15.9 4.7 0.0038 15.6 4.7 1.1 1 0 0 1 1 1 1 CDC45-like protein MobB PF03205.14 ORY93197.1 - 0.0041 17.0 0.1 0.07 13.0 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 ORY93197.1 - 0.0053 16.3 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 ORY93197.1 - 0.012 15.8 1.3 0.016 15.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY93197.1 - 0.016 15.4 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY93197.1 - 0.022 14.5 0.0 0.35 10.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 ORY93197.1 - 0.023 14.1 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 ORY93197.1 - 0.04 14.3 0.1 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 ORY93197.1 - 0.05 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 ORY93197.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TFIIE-A_C PF11521.8 ORY93197.1 - 0.064 13.6 4.2 7 7.0 1.7 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha cobW PF02492.19 ORY93197.1 - 0.11 12.1 0.2 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ORY93197.1 - 0.12 12.7 7.2 0.047 14.1 3.4 2.3 2 1 0 2 2 1 0 AAA ATPase domain Dynamin_N PF00350.23 ORY93197.1 - 0.13 12.3 2.2 2.9 7.9 0.1 2.6 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 ORY93197.1 - 0.14 11.6 0.4 3.2 7.1 0.4 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 ORY93197.1 - 0.15 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 ORY93197.1 - 0.15 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SH3_1 PF00018.28 ORY93198.1 - 2.7e-12 46.1 0.0 4.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY93198.1 - 3.2e-09 36.3 0.0 6.3e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY93198.1 - 1.5e-07 31.1 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 ORY93198.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Tetraspanin PF00335.20 ORY93198.1 - 0.12 12.1 5.4 0.086 12.5 3.4 1.7 2 0 0 2 2 2 0 Tetraspanin family DUF962 PF06127.11 ORY93198.1 - 0.33 11.1 2.0 2.8 8.1 2.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF962) OHCU_decarbox PF09349.10 ORY93199.1 - 1.3e-43 149.2 0.0 1.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Peptidase_M24 PF00557.24 ORY93200.1 - 2.4e-21 76.4 0.5 2.8e-21 76.2 0.5 1.2 1 1 0 1 1 1 1 Metallopeptidase family M24 DEAD PF00270.29 ORY93201.1 - 1.1e-48 165.3 0.1 7.5e-47 159.3 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY93201.1 - 1.3e-30 106.0 0.1 4.8e-30 104.1 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY93201.1 - 7.1e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ORY93201.1 - 0.00058 19.6 0.1 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase UPF0020 PF01170.18 ORY93202.1 - 4.3e-20 72.2 0.1 4.4e-19 68.9 0.1 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 ORY93202.1 - 2.7e-07 31.2 0.0 1.1e-06 29.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY93202.1 - 7.9e-07 28.7 0.0 2.3e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 ORY93202.1 - 2.5e-06 27.0 0.0 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY93202.1 - 4.3e-05 23.1 0.0 0.0024 17.4 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORY93202.1 - 0.0002 21.9 0.0 0.00043 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY93202.1 - 0.0023 17.6 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 ORY93202.1 - 0.022 14.6 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain N6_Mtase PF02384.16 ORY93202.1 - 0.12 11.6 0.0 0.59 9.3 0.0 2.0 1 1 0 1 1 1 0 N-6 DNA Methylase TP_methylase PF00590.20 ORY93203.1 - 9.3e-22 78.0 0.0 1.4e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Lactamase_B_2 PF12706.7 ORY93204.1 - 9.4e-27 93.8 0.0 3.9e-26 91.8 0.0 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY93204.1 - 0.00013 22.0 0.9 0.00046 20.3 0.9 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PQ-loop PF04193.14 ORY93205.1 - 1.1e-20 73.2 18.0 1.3e-12 47.3 0.5 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF2721 PF11026.8 ORY93205.1 - 0.0044 16.9 0.1 0.0044 16.9 0.1 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF2721) L27_2 PF09045.10 ORY93205.1 - 0.091 12.7 0.1 0.82 9.7 0.1 2.2 2 0 0 2 2 2 0 L27_2 MtN3_slv PF03083.16 ORY93205.1 - 0.84 9.7 7.9 1.2 9.2 1.4 3.0 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF4191 PF13829.6 ORY93205.1 - 2.6 7.3 6.0 0.98 8.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Hexokinase_2 PF03727.16 ORY93206.1 - 1.3e-74 250.7 0.0 1.8e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY93206.1 - 2.8e-49 167.8 0.0 4.7e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.16 ORY93208.1 - 6.8e-32 110.8 62.4 4.8e-25 88.2 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY93208.1 - 1.3e-05 24.0 24.3 0.0061 15.2 6.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein ATP1G1_PLM_MAT8 PF02038.16 ORY93208.1 - 6.4 6.3 8.9 0.76 9.3 2.0 2.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family CENP-X PF09415.10 ORY93209.1 - 1.8e-21 76.2 0.1 2.3e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Phage_TAC_2 PF06894.11 ORY93209.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Nop25 PF09805.9 ORY93210.1 - 7e-22 78.4 25.0 1e-21 77.8 25.0 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) CDC27 PF09507.10 ORY93210.1 - 0.32 10.4 22.0 0.37 10.1 22.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Syja_N PF02383.18 ORY93211.1 - 1.1e-96 324.0 0.0 1.5e-96 323.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain LAGLIDADG_3 PF14528.6 ORY93212.1 - 0.057 13.7 0.0 12 6.3 0.0 3.0 3 0 0 3 3 3 0 LAGLIDADG-like domain zf-C2H2_4 PF13894.6 ORY93213.1 - 2.4e-06 27.9 26.5 0.038 14.8 3.6 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY93213.1 - 0.00045 20.4 12.3 0.015 15.4 1.3 2.6 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY93213.1 - 0.031 14.7 2.0 0.031 14.7 2.0 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF4729 PF15866.5 ORY93213.1 - 0.23 10.8 10.2 0.13 11.5 1.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4729) zf_Hakai PF18408.1 ORY93213.1 - 0.24 11.1 0.1 0.24 11.1 0.1 3.0 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain DUF629 PF04780.12 ORY93213.1 - 0.27 9.7 3.9 5.5 5.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) FOXP-CC PF16159.5 ORY93213.1 - 4 8.2 5.5 19 5.9 0.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain HOOK PF05622.12 ORY93214.1 - 7.8e-22 77.2 50.7 4.1e-17 61.6 20.6 3.8 1 1 2 3 3 3 2 HOOK protein bZIP_1 PF00170.21 ORY93214.1 - 0.0041 17.2 2.9 0.0041 17.2 2.9 6.1 4 2 2 6 6 6 2 bZIP transcription factor Paf67 PF10255.9 ORY93214.1 - 0.0058 15.7 0.6 0.0058 15.7 0.6 1.9 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 MAD PF05557.13 ORY93214.1 - 0.029 12.8 38.9 0.21 9.9 23.7 3.0 2 1 0 2 2 2 0 Mitotic checkpoint protein NYD-SP28_assoc PF14775.6 ORY93214.1 - 0.03 14.4 3.4 0.03 14.4 3.4 5.7 5 1 0 5 5 5 0 Sperm tail C-terminal domain Spc7 PF08317.11 ORY93214.1 - 0.06 12.2 43.5 0.13 11.1 6.5 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 ORY93214.1 - 0.11 12.8 34.0 0.084 13.2 5.2 5.1 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Noelin-1 PF12308.8 ORY93214.1 - 5 7.2 20.1 0.059 13.4 1.7 4.1 3 2 2 5 5 5 0 Neurogenesis glycoprotein HOOK PF05622.12 ORY93215.1 - 2.9e-26 91.9 1.5 4.5e-26 91.2 1.5 1.3 1 0 0 1 1 1 1 HOOK protein RB_A PF01858.17 ORY93215.1 - 0.047 13.5 1.6 0.12 12.2 0.5 2.0 1 1 1 2 2 2 0 Retinoblastoma-associated protein A domain MCM_N PF14551.6 ORY93215.1 - 0.063 13.9 0.1 0.18 12.4 0.1 1.9 1 0 0 1 1 1 0 MCM N-terminal domain 2-Hacid_dh_C PF02826.19 ORY93216.1 - 3.7e-56 189.3 0.0 5.7e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY93216.1 - 1.4e-31 109.0 0.0 1.6e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY93216.1 - 0.00075 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY93216.1 - 0.049 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 ORY93216.1 - 0.11 13.0 0.0 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 ORY93216.1 - 0.14 12.2 0.0 0.99 9.5 0.0 2.2 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Cylicin_N PF15241.6 ORY93217.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Cylicin N-terminus Gar1 PF04410.14 ORY93218.1 - 4.7e-37 127.1 0.1 4.7e-37 127.1 0.1 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region CENP-L PF13092.6 ORY93219.1 - 8e-14 52.2 0.1 1.3e-13 51.5 0.1 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 F-box-like PF12937.7 ORY93221.1 - 0.017 15.0 0.3 0.041 13.8 0.3 1.7 1 0 0 1 1 1 0 F-box-like ER_lumen_recept PF00810.18 ORY93223.1 - 1.3e-55 188.2 10.3 2.3e-55 187.5 10.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ORY93223.1 - 0.053 13.3 14.2 0.21 11.4 0.2 4.0 5 0 0 5 5 5 0 PQ loop repeat Glyco_hydro_15 PF00723.21 ORY93224.1 - 1.1e-82 278.2 2.0 1.4e-82 277.9 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Spem1 PF15670.5 ORY93225.1 - 2 8.0 16.6 0.87 9.1 8.8 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 Methyltransf_31 PF13847.6 ORY93226.1 - 3.7e-06 26.8 0.0 6.8e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY93226.1 - 6.8e-06 26.7 0.0 1.3e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93226.1 - 4.8e-05 24.0 0.0 7.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY93226.1 - 0.00015 22.3 0.0 0.00027 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY93226.1 - 0.047 13.7 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mitofilin PF09731.9 ORY93227.1 - 1e-79 269.1 37.8 5.1e-70 237.0 33.2 2.2 1 1 1 2 2 2 2 Mitochondrial inner membrane protein MRP-S27 PF10037.9 ORY93227.1 - 0.015 14.1 9.5 0.027 13.3 9.5 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Prominin PF05478.11 ORY93227.1 - 0.063 11.2 10.9 0.13 10.2 10.6 1.6 1 1 1 2 2 2 0 Prominin ArsR PF09824.9 ORY93227.1 - 0.085 12.5 1.2 0.26 10.9 0.1 2.3 2 1 1 3 3 3 0 ArsR transcriptional regulator Aminotran_1_2 PF00155.21 ORY93227.1 - 0.09 11.9 1.3 0.21 10.7 1.3 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II GvpL_GvpF PF06386.11 ORY93227.1 - 0.53 10.2 19.6 0.58 10.1 16.5 2.6 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF TMPIT PF07851.13 ORY93227.1 - 0.85 8.8 5.4 1.7 7.8 5.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 ORY93227.1 - 1.6 7.7 13.5 0.76 8.8 10.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XRN_M PF17846.1 ORY93227.1 - 1.8 7.4 6.9 2.7 6.9 6.9 1.3 1 0 0 1 1 1 0 Xrn1 helical domain MFS_1 PF07690.16 ORY93228.1 - 1.4e-28 99.8 61.5 1.3e-26 93.4 44.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 ORY93229.1 - 0.00062 19.6 0.1 0.0022 17.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY93229.1 - 0.0035 17.2 0.3 0.022 14.6 0.1 2.5 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.16 ORY93230.1 - 8.8e-24 84.1 52.1 2.2e-20 72.9 31.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zds_C PF08632.10 ORY93231.1 - 7.6e-27 92.8 2.3 1.6e-26 91.8 2.3 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF3439 PF11921.8 ORY93231.1 - 3.7 7.5 11.1 1.4 8.9 8.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Zn_clus PF00172.18 ORY93232.1 - 6.1e-06 26.3 9.0 1.1e-05 25.4 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF104 PF01954.16 ORY93232.1 - 0.18 12.2 0.1 0.38 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 zf-C2H2 PF00096.26 ORY93233.1 - 2.1e-19 68.8 25.1 2.5e-05 24.5 0.4 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY93233.1 - 2.5e-13 49.6 21.4 0.014 16.2 0.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY93233.1 - 3.8e-11 42.9 31.0 6e-07 29.6 1.3 5.7 6 0 0 6 6 5 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 ORY93233.1 - 0.0011 19.1 11.7 0.39 10.8 0.3 4.0 1 1 3 4 4 4 2 Aberrant zinc-finger RskA PF10099.9 ORY93233.1 - 0.0039 17.5 0.4 0.0047 17.2 0.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA zf-C2H2_8 PF15909.5 ORY93233.1 - 0.0078 16.5 8.7 0.01 16.1 1.3 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY93233.1 - 0.094 13.4 0.1 0.094 13.4 0.1 5.2 2 1 2 4 4 3 0 FOXP coiled-coil domain Spt20 PF12090.8 ORY93233.1 - 0.12 12.0 13.1 0.15 11.6 13.1 1.2 1 0 0 1 1 1 0 Spt20 family SRA1 PF07304.11 ORY93233.1 - 0.13 12.0 2.6 0.22 11.3 2.6 1.3 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) TFIIA PF03153.13 ORY93233.1 - 0.23 11.4 18.2 0.24 11.3 18.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CHORD PF04968.12 ORY93233.1 - 0.31 11.8 17.4 2.8 8.7 0.3 4.6 1 1 3 4 4 4 0 CHORD zf-DNA_Pol PF08996.10 ORY93233.1 - 0.33 10.7 9.1 0.82 9.4 0.6 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 ORY93233.1 - 0.51 10.4 0.1 0.51 10.4 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger IBR PF01485.21 ORY93233.1 - 1.3 9.3 15.0 0.088 13.0 0.9 3.3 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain F-box PF00646.33 ORY93234.1 - 0.15 12.0 0.3 0.15 12.0 0.3 3.4 3 0 0 3 3 3 0 F-box domain RGS PF00615.19 ORY93235.1 - 0.00031 21.0 0.0 0.014 15.7 0.0 2.6 2 1 0 2 2 2 1 Regulator of G protein signaling domain DUF1351 PF07083.11 ORY93236.1 - 0.0037 17.1 1.2 0.0056 16.5 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) Retrotrans_gag PF03732.17 ORY93236.1 - 0.068 13.4 4.0 0.15 12.3 1.0 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein FUSC PF04632.12 ORY93236.1 - 0.091 11.3 0.7 0.1 11.1 0.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 ORY93236.1 - 3.2 8.1 10.4 4.1 7.7 8.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FYVE PF01363.21 ORY93237.1 - 1.1e-13 51.1 15.4 1.6e-13 50.6 14.3 1.9 1 1 0 1 1 1 1 FYVE zinc finger YabA PF06156.13 ORY93237.1 - 0.0038 17.8 3.6 0.0069 17.0 3.6 1.4 1 0 0 1 1 1 1 Initiation control protein YabA TFIIA PF03153.13 ORY93237.1 - 0.054 13.5 13.0 0.062 13.3 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 ORY93237.1 - 0.094 12.4 5.2 0.14 11.9 5.2 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spt20 PF12090.8 ORY93237.1 - 0.23 11.1 15.9 0.28 10.7 15.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 ORY93237.1 - 0.52 9.2 14.1 0.23 10.4 12.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) zf-AN1 PF01428.16 ORY93237.1 - 0.66 10.2 13.5 0.12 12.5 9.3 1.9 2 0 0 2 2 2 0 AN1-like Zinc finger TERB2 PF15101.6 ORY93237.1 - 2.1 8.4 9.8 2.9 7.9 9.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 ORY93237.1 - 4.1 6.1 5.1 4.7 5.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin SUIM_assoc PF16619.5 ORY93237.1 - 6.4 6.9 19.9 17 5.5 19.9 1.8 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Thr_synth_N PF14821.6 ORY93238.1 - 1.8e-27 95.3 0.0 3.6e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 ORY93238.1 - 2e-14 53.7 0.2 9.4e-14 51.5 0.2 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PH PF00169.29 ORY93239.1 - 0.007 16.9 0.0 3.1 8.4 0.0 2.6 2 0 0 2 2 2 2 PH domain Ribosomal_L9_C PF03948.14 ORY93240.1 - 5.2e-13 49.3 0.3 9.4e-13 48.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 ORY93240.1 - 1.5e-11 43.7 0.1 3e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain YlqD PF11068.8 ORY93240.1 - 0.0098 16.3 0.2 0.016 15.6 0.2 1.3 1 0 0 1 1 1 1 YlqD protein LRR_8 PF13855.6 ORY93241.1 - 1.4e-16 60.0 24.7 8.7e-08 31.8 4.4 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY93241.1 - 3.7e-13 49.4 12.5 2.1e-08 34.3 0.4 4.1 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY93241.1 - 4.8e-07 29.4 5.4 0.27 11.9 0.0 5.5 4 2 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY93241.1 - 5.6e-05 22.9 7.8 0.047 13.7 0.0 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 ORY93241.1 - 0.00024 20.6 0.1 0.00042 19.9 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Alba PF01918.21 ORY93242.1 - 6.2e-17 61.2 2.4 9.6e-17 60.6 2.4 1.3 1 0 0 1 1 1 1 Alba Cellulase PF00150.18 ORY93242.1 - 0.0027 17.2 0.0 0.0032 16.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3530 PF12048.8 ORY93242.1 - 0.041 13.3 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pyocin_S PF06958.12 ORY93242.1 - 0.063 13.8 0.2 0.08 13.5 0.2 1.2 1 0 0 1 1 1 0 S-type Pyocin DRIM PF07539.12 ORY93243.1 - 3.3e-153 511.3 7.2 8e-153 510.0 0.0 4.1 3 1 0 4 4 4 1 Down-regulated in metastasis HEAT PF02985.22 ORY93243.1 - 0.011 15.9 0.2 2.2 8.7 0.1 3.8 2 0 0 2 2 2 0 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY93243.1 - 0.022 15.3 1.8 1.3 9.7 0.1 4.5 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region PsiA PF06952.11 ORY93243.1 - 0.038 13.2 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 PsiA protein Tti2 PF10521.9 ORY93243.1 - 0.045 13.3 4.7 0.46 10.0 0.0 4.1 4 1 1 5 5 5 0 Tti2 family Pneumovirus_M2 PF06436.11 ORY93243.1 - 0.14 11.7 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) MMS19_N PF14500.6 ORY93243.1 - 0.32 10.5 5.5 5.1 6.6 2.4 4.2 2 2 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II GP24_25 PF17388.2 ORY93243.1 - 0.63 10.0 6.6 0.34 10.9 0.1 3.6 5 0 0 5 5 5 0 Tail assembly gene products 24 & 25 Arg_decarbox_C PF17944.1 ORY93243.1 - 4.7 7.8 5.1 8.3 7.1 0.5 3.5 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Rhomboid PF01694.22 ORY93244.1 - 7.3e-26 91.0 11.9 7.3e-26 91.0 11.9 2.0 3 0 0 3 3 3 1 Rhomboid family MnhB PF04039.13 ORY93244.1 - 0.69 10.2 8.4 0.18 12.2 0.8 3.1 3 1 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Abhydrolase_3 PF07859.13 ORY93245.1 - 2.4e-65 220.3 0.0 3e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY93245.1 - 4.1e-09 35.8 0.0 5.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY93245.1 - 1.4e-08 34.1 0.0 3.3e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORY93245.1 - 4.9e-06 26.2 0.0 0.035 13.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.9 ORY93245.1 - 1.1e-05 25.1 0.0 0.0019 17.7 0.0 2.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 ORY93245.1 - 4.3e-05 22.5 0.0 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORY93245.1 - 0.064 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase MtrC PF04211.13 ORY93245.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Esterase PF00756.20 ORY93245.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.6 1 1 1 2 2 2 0 Putative esterase Abhydrolase_3 PF07859.13 ORY93246.1 - 3.6e-59 200.2 0.0 4.8e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY93246.1 - 2.2e-11 43.2 0.0 2.9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY93246.1 - 5.9e-07 28.7 0.2 1.5e-06 27.4 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 ORY93246.1 - 0.0012 18.4 0.2 0.074 12.5 0.2 2.2 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY93246.1 - 0.0033 16.9 0.0 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORY93246.1 - 0.067 13.8 0.7 0.25 11.9 0.7 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fez1 PF06818.15 ORY93247.1 - 2.4e-06 28.2 32.5 5.3e-06 27.0 13.6 2.1 1 1 1 2 2 2 1 Fez1 Atg14 PF10186.9 ORY93247.1 - 3.6e-05 23.0 19.3 0.003 16.7 3.1 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 ORY93247.1 - 0.00041 20.5 13.7 0.00041 20.5 13.7 3.4 3 1 1 4 4 3 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 ORY93247.1 - 0.00058 19.9 27.9 0.071 13.1 10.4 2.4 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 ORY93247.1 - 0.0017 18.2 0.4 0.0017 18.2 0.4 3.6 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4201 PF13870.6 ORY93247.1 - 0.0022 17.8 28.2 0.0024 17.6 8.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) FUSC PF04632.12 ORY93247.1 - 0.0029 16.2 6.9 0.0044 15.6 6.9 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family Tropomyosin_1 PF12718.7 ORY93247.1 - 0.003 17.7 15.5 0.003 17.7 15.5 2.9 2 2 0 2 2 2 1 Tropomyosin like Vps5 PF09325.10 ORY93247.1 - 0.01 15.4 4.9 0.01 15.4 4.9 2.3 2 0 0 2 2 2 0 Vps5 C terminal like Tmpp129 PF10272.9 ORY93247.1 - 0.013 14.8 0.4 0.02 14.2 0.4 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor TMPIT PF07851.13 ORY93247.1 - 0.017 14.4 13.6 0.014 14.6 2.4 2.3 2 0 0 2 2 2 0 TMPIT-like protein Prominin PF05478.11 ORY93247.1 - 0.028 12.4 14.2 0.011 13.7 5.7 2.1 2 0 0 2 2 2 0 Prominin TolA_bind_tri PF16331.5 ORY93247.1 - 0.047 13.8 38.7 0.08 13.0 3.2 4.2 2 2 1 4 4 4 0 TolA binding protein trimerisation ZapB PF06005.12 ORY93247.1 - 0.052 14.0 31.9 0.57 10.7 0.3 3.9 3 1 0 3 3 3 0 Cell division protein ZapB Cas_GSU0053 PF09617.10 ORY93247.1 - 0.056 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Spc7 PF08317.11 ORY93247.1 - 0.086 11.7 31.7 0.0094 14.9 16.9 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 ORY93247.1 - 0.095 12.0 37.9 0.45 9.8 18.7 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 ORY93247.1 - 0.13 11.7 29.2 0.45 10.0 10.1 2.1 1 1 1 2 2 2 0 Leucine zipper EzrA PF06160.12 ORY93247.1 - 0.16 10.2 25.5 1.6 6.8 25.5 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Lebercilin PF15619.6 ORY93247.1 - 0.18 11.5 30.6 0.49 10.0 10.7 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 ORY93247.1 - 0.26 11.4 33.7 1.1 9.3 10.5 2.8 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase MPS2 PF17060.5 ORY93247.1 - 0.29 10.4 18.0 0.023 14.0 1.6 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 Occludin_ELL PF07303.13 ORY93247.1 - 0.59 10.9 17.4 1.4 9.7 1.4 3.7 2 2 2 4 4 4 0 Occludin homology domain FapA PF03961.13 ORY93247.1 - 0.6 8.7 20.7 0.52 8.9 4.9 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Speriolin_N PF15058.6 ORY93247.1 - 0.7 10.0 3.8 0.7 10.0 0.1 2.3 2 0 0 2 2 2 0 Speriolin N terminus Phage_GP20 PF06810.11 ORY93247.1 - 0.75 9.6 28.4 0.19 11.5 10.3 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF1664 PF07889.12 ORY93247.1 - 1.1 9.4 14.1 0.93 9.5 1.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2353 PF09789.9 ORY93247.1 - 1.1 8.6 28.2 0.36 10.1 8.6 2.8 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF3450 PF11932.8 ORY93247.1 - 1.3 8.2 26.5 3.1 7.0 9.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) KLRAQ PF10205.9 ORY93247.1 - 1.4 9.2 20.3 0.3 11.4 5.3 2.9 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Golgin_A5 PF09787.9 ORY93247.1 - 1.7 8.1 30.6 6.5 6.1 29.6 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 TraF_2 PF13729.6 ORY93247.1 - 2.1 7.7 17.0 0.19 11.1 2.3 3.0 1 1 2 3 3 3 0 F plasmid transfer operon, TraF, protein YabA PF06156.13 ORY93247.1 - 2.3 8.9 28.0 0.68 10.6 6.2 3.6 2 2 1 3 3 2 0 Initiation control protein YabA GrpE PF01025.19 ORY93247.1 - 2.8 7.6 27.1 0.74 9.5 6.7 3.3 2 1 1 3 3 3 0 GrpE NPV_P10 PF05531.12 ORY93247.1 - 2.9 8.4 12.3 0.82 10.2 4.3 3.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 ORY93247.1 - 3.4 6.9 25.6 1.7 7.9 15.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 ORY93247.1 - 3.7 7.6 38.0 1.4 8.9 12.2 2.9 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Borrelia_orfA PF02414.15 ORY93247.1 - 3.7 7.1 12.3 2.1 7.9 2.0 2.2 2 0 0 2 2 2 0 Borrelia ORF-A Seryl_tRNA_N PF02403.22 ORY93247.1 - 3.8 7.8 29.6 7.6 6.8 11.3 2.9 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KASH_CCD PF14662.6 ORY93247.1 - 4 7.2 35.9 0.26 11.1 11.4 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 ORY93247.1 - 5.5 4.4 31.1 11 3.3 31.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CT_C_D PF02682.16 ORY93247.1 - 5.5 6.7 5.1 17 5.1 0.5 2.4 2 1 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D COG2 PF06148.11 ORY93247.1 - 6.8 6.8 19.1 0.35 10.9 4.5 3.2 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.8 ORY93247.1 - 7.7 6.6 44.3 0.054 13.5 17.0 3.7 3 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding AKNA PF12443.8 ORY93247.1 - 8.4 7.1 18.1 0.54 10.9 4.5 3.5 2 2 2 4 4 4 0 AT-hook-containing transcription factor Rx_N PF18052.1 ORY93247.1 - 9 6.6 18.9 2.6 8.4 2.1 3.6 2 1 1 3 3 3 0 Rx N-terminal domain Sec34 PF04136.15 ORY93247.1 - 10 6.0 17.8 9.7 6.1 5.0 2.7 2 1 0 2 2 2 0 Sec34-like family Zn_clus PF00172.18 ORY93248.1 - 1.8e-07 31.1 8.0 5.2e-07 29.7 8.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY93248.1 - 0.012 14.7 0.4 0.019 14.0 0.4 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain RRM_1 PF00076.22 ORY93249.1 - 2.8e-13 49.5 0.0 3.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY93249.1 - 0.0058 16.6 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3020 PF11223.8 ORY93250.1 - 6.5e-20 71.4 9.9 6.5e-20 71.4 9.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) RskA PF10099.9 ORY93250.1 - 0.0029 17.9 26.7 0.0029 17.9 1.6 2.8 1 1 0 2 2 2 2 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 ORY93250.1 - 0.8 10.3 25.6 0.29 11.8 7.8 3.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein SUIM_assoc PF16619.5 ORY93250.1 - 5.2 7.2 34.3 0.034 14.2 12.1 4.6 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Dus PF01207.17 ORY93252.1 - 4e-76 256.1 0.0 5.1e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 ORY93252.1 - 0.00051 19.9 0.3 0.0013 18.6 0.2 1.6 1 1 1 2 2 2 1 SOR/SNZ family NMO PF03060.15 ORY93252.1 - 0.0086 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ORY93252.1 - 0.022 13.8 0.1 0.033 13.2 0.1 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 ORY93252.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 ORY93252.1 - 0.079 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 ORY93252.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Methyltransf_25 PF13649.6 ORY93253.1 - 1.6e-15 57.6 0.0 9.8e-15 55.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY93253.1 - 6.3e-15 55.6 0.0 1.3e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY93253.1 - 6.4e-13 48.9 0.0 9.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY93253.1 - 5.8e-10 39.2 0.0 8.2e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY93253.1 - 7.9e-08 31.9 0.0 5.1e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY93253.1 - 4.6e-06 27.3 0.0 2.5e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORY93253.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 ORY93253.1 - 0.007 16.5 0.0 0.0098 16.0 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 ORY93253.1 - 0.034 13.8 0.0 0.091 12.3 0.0 1.8 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 ORY93253.1 - 0.045 13.3 0.0 0.16 11.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 ORY93253.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 ORY93253.1 - 0.084 12.3 0.0 0.58 9.6 0.0 2.2 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_2 PF00891.18 ORY93253.1 - 0.14 11.4 0.0 0.4 10.0 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase domain FMN_dh PF01070.18 ORY93254.1 - 1.3e-122 409.2 0.1 1.6e-122 408.9 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY93254.1 - 1.6e-25 89.1 0.0 6.8e-25 87.0 0.0 2.1 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ORY93254.1 - 8.2e-09 35.1 0.0 2.2e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 ORY93254.1 - 3e-05 23.6 0.1 6e-05 22.6 0.1 1.5 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 ORY93254.1 - 9.3e-05 21.6 0.2 0.00031 19.9 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 ORY93254.1 - 0.002 17.6 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 ORY93254.1 - 0.0069 15.7 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ORY93254.1 - 0.11 11.9 0.2 1.1 8.7 0.1 2.1 1 1 0 2 2 2 0 Histidine biosynthesis protein NIF PF03031.18 ORY93255.1 - 3.5e-53 179.5 0.4 4.1e-53 179.3 0.4 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORY93255.1 - 0.0065 16.9 0.1 0.067 13.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CytoC_RC PF02276.18 ORY93255.1 - 0.25 10.7 0.0 8.4 5.7 0.0 2.0 2 0 0 2 2 2 0 Photosynthetic reaction centre cytochrome C subunit PHD PF00628.29 ORY93256.1 - 1e-06 28.5 5.3 2.1e-06 27.5 5.3 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 ORY93256.1 - 0.00035 20.4 1.0 0.00071 19.5 1.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_Oberon PF07227.11 ORY93256.1 - 0.037 13.9 2.6 0.071 13.0 2.6 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein IlvN PF07991.12 ORY93257.1 - 1.7e-50 170.8 0.2 2.4e-50 170.3 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORY93257.1 - 1.8e-19 70.4 0.0 3.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 ORY93257.1 - 1.5e-08 35.1 0.1 3.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORY93257.1 - 6.1e-06 26.5 0.0 9.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 ORY93257.1 - 6.1e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY93257.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 ORY93257.1 - 0.0043 17.1 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ORY93257.1 - 0.0098 16.3 0.1 0.025 15.0 0.1 1.7 1 1 1 2 2 2 1 Putative NAD(P)-binding PDH PF02153.17 ORY93257.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 ORY93257.1 - 0.15 12.1 0.3 3.9 7.4 0.3 2.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RRM_1 PF00076.22 ORY93258.1 - 3.7e-17 61.9 0.0 4.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY93258.1 - 0.0035 16.9 0.0 0.0048 16.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY93258.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Limkain b1 Mito_carr PF00153.27 ORY93259.1 - 1.3e-21 76.3 0.2 1.2e-05 25.1 0.0 5.1 5 0 0 5 5 5 5 Mitochondrial carrier protein V-ATPase_H_N PF03224.14 ORY93260.1 - 1.3e-76 258.0 0.4 2.7e-76 256.9 0.4 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORY93260.1 - 1.1e-34 119.0 0.2 3e-33 114.4 0.0 2.8 2 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 ORY93260.1 - 0.064 13.3 0.0 82 3.4 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Aminotran_1_2 PF00155.21 ORY93262.1 - 2.4e-53 181.6 0.0 3.1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY93262.1 - 0.00031 20.1 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase F-box-like PF12937.7 ORY93263.1 - 0.00012 21.8 0.3 0.00026 20.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like TbpB_C PF17483.2 ORY93263.1 - 0.048 14.0 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B TPR_2 PF07719.17 ORY93263.1 - 0.069 13.3 0.3 1.7 9.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY93263.1 - 0.075 13.1 1.2 1.9 8.7 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Cation_ATPase_C PF00689.21 ORY93264.1 - 6.8e-43 146.5 10.3 6.8e-43 146.5 10.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY93264.1 - 4.5e-37 127.3 0.9 4.5e-37 127.3 0.9 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY93264.1 - 1.2e-22 79.8 0.1 2.5e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY93264.1 - 3.5e-16 60.1 5.7 9.6e-16 58.7 5.7 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY93264.1 - 2.4e-13 49.5 0.0 5.1e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY93264.1 - 0.0067 16.2 0.4 0.02 14.6 0.4 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Arylesterase PF01731.20 ORY93265.1 - 5.6e-10 39.3 0.1 5e-09 36.2 0.1 2.3 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 ORY93265.1 - 0.014 15.5 0.0 0.04 14.0 0.0 1.8 1 0 0 1 1 1 0 Strictosidine synthase US22 PF02393.16 ORY93265.1 - 0.064 13.5 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 US22 like UQ_con PF00179.26 ORY93266.1 - 3.3e-55 185.6 0.0 3.7e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY93266.1 - 0.0019 18.5 0.0 0.0036 17.6 0.0 1.6 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.6 ORY93266.1 - 0.0076 16.0 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY93266.1 - 0.056 13.3 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain PhyH PF05721.13 ORY93267.1 - 7.2e-24 85.2 0.1 4.2e-23 82.7 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 ORY93267.1 - 0.00096 20.0 0.0 0.0019 19.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CpeS PF09367.10 ORY93267.1 - 0.075 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 CpeS-like protein Ank_5 PF13857.6 ORY93268.1 - 6e-37 125.2 6.9 2.1e-11 43.8 0.1 5.9 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY93268.1 - 2.3e-33 114.2 6.4 2e-07 31.4 0.2 7.2 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY93268.1 - 4.7e-32 110.4 4.0 6.8e-10 39.4 0.0 6.2 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY93268.1 - 9.1e-23 77.9 4.8 0.0027 18.1 0.1 8.5 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 ORY93268.1 - 1.7e-20 72.5 21.8 0.0002 21.7 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Golgin_A5 PF09787.9 ORY93268.1 - 0.0019 17.7 15.1 0.0019 17.7 15.1 3.5 3 0 0 3 3 3 1 Golgin subfamily A member 5 SKA2 PF16740.5 ORY93268.1 - 0.46 10.3 22.4 1.8 8.4 0.2 4.9 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 2 FlaC_arch PF05377.11 ORY93268.1 - 0.75 10.2 15.4 16 6.0 0.1 6.2 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 ORY93268.1 - 1.2 9.4 15.6 0.84 9.9 3.6 4.7 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Cnn_1N PF07989.11 ORY93268.1 - 3.4 7.9 18.4 2.3 8.5 1.0 4.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DASH_Duo1 PF08651.10 ORY93268.1 - 5.5 6.8 10.9 0.51 10.1 0.7 4.1 4 0 0 4 4 4 0 DASH complex subunit Duo1 CRAL_TRIO PF00650.20 ORY93270.1 - 1e-27 96.8 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY93270.1 - 0.014 15.6 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RabGAP-TBC PF00566.18 ORY93272.1 - 3.1e-48 164.3 0.0 5.1e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cullin_binding PF03556.15 ORY93272.1 - 0.15 12.5 1.6 0.25 11.8 0.3 2.0 2 0 0 2 2 2 0 Cullin binding zf-C2H2 PF00096.26 ORY93273.1 - 4.3e-07 30.0 14.5 0.00027 21.2 2.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY93273.1 - 0.00087 19.6 2.1 0.00087 19.6 2.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY93273.1 - 0.0014 18.9 2.2 0.91 9.9 0.3 2.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 ORY93273.1 - 0.049 14.0 2.4 2 8.9 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORY93273.1 - 0.062 13.0 2.4 0.15 11.8 2.4 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF4619 PF15398.6 ORY93273.1 - 0.062 12.8 3.9 0.1 12.1 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) FOXP-CC PF16159.5 ORY93273.1 - 0.15 12.7 11.5 0.95 10.1 1.4 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORY93273.1 - 0.66 10.0 5.0 3.2 7.8 0.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger AAA_5 PF07728.14 ORY93274.1 - 2.7e-90 299.5 0.0 2.3e-35 121.6 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY93274.1 - 2.9e-09 37.6 0.6 0.025 15.0 0.0 5.1 3 2 1 5 5 5 2 AAA ATPase domain CbbQ_C PF08406.10 ORY93274.1 - 3.8e-06 27.1 0.2 0.0016 18.6 0.3 2.9 2 0 0 2 2 2 1 CbbQ/NirQ/NorQ C-terminal AAA_3 PF07726.11 ORY93274.1 - 1.6e-05 24.8 0.1 0.78 9.6 0.0 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 ORY93274.1 - 0.00018 21.6 0.1 0.53 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 ORY93274.1 - 0.0021 17.5 0.2 6.5 6.1 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY93274.1 - 0.019 15.5 0.6 3.9 8.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain MCM6_C PF18263.1 ORY93274.1 - 0.02 15.1 0.0 0.08 13.2 0.0 2.1 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain TsaE PF02367.17 ORY93274.1 - 0.065 13.2 0.0 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 ORY93274.1 - 0.1 12.4 0.2 0.53 10.0 0.1 2.3 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ORY93274.1 - 0.16 12.4 0.0 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Csm2_III-A PF03750.13 ORY93274.1 - 0.18 12.7 0.7 2.5 9.0 0.2 2.5 2 0 0 2 2 2 0 Csm2 Type III-A RhoGEF PF00621.20 ORY93276.1 - 1.1e-24 87.7 0.5 3.1e-24 86.2 0.1 1.9 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 ORY93276.1 - 3.2e-16 59.7 1.7 6.8e-16 58.6 1.7 1.5 1 0 0 1 1 1 1 BAR domain PLU-1 PF08429.11 ORY93276.1 - 0.037 13.2 0.3 0.063 12.4 0.3 1.4 1 0 0 1 1 1 0 PLU-1-like protein Phage_cap_E PF03864.15 ORY93276.1 - 0.039 13.1 0.7 0.29 10.3 1.1 2.0 2 0 0 2 2 2 0 Phage major capsid protein E SesA PF17107.5 ORY93276.1 - 0.041 14.1 0.9 4.2 7.6 0.2 3.4 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ISG65-75 PF11727.8 ORY93276.1 - 0.066 12.4 0.9 0.77 8.9 0.5 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein BORCS6 PF10157.9 ORY93276.1 - 0.17 12.1 0.5 1.3 9.2 0.2 2.5 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 6 DUF937 PF06078.11 ORY93276.1 - 0.18 12.4 0.0 1.9 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) NIT PF08376.10 ORY93276.1 - 0.73 10.2 6.3 1.6 9.1 0.7 2.6 2 1 1 3 3 3 0 Nitrate and nitrite sensing RhoGEF PF00621.20 ORY93277.1 - 3.6e-11 43.6 0.2 7.2e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain MFS_1 PF07690.16 ORY93278.1 - 8.5e-22 77.6 27.9 1e-21 77.3 27.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CCSMST1 PF15013.6 ORY93278.1 - 0.21 11.7 0.1 0.55 10.4 0.1 1.6 1 0 0 1 1 1 0 CCSMST1 family Sugar_tr PF00083.24 ORY93278.1 - 0.4 9.5 23.1 0.022 13.6 3.9 3.1 1 1 2 3 3 3 0 Sugar (and other) transporter Abhydrolase_3 PF07859.13 ORY93279.1 - 4e-14 53.0 0.6 7.7e-13 48.8 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY93279.1 - 4.1e-12 46.0 0.0 9.9e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ORY93279.1 - 1.5e-09 37.3 0.0 0.0008 18.4 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 ORY93279.1 - 2.4e-08 33.5 0.4 0.00018 20.9 0.0 2.6 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY93279.1 - 4.5e-07 30.7 4.7 1.1e-06 29.4 4.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORY93279.1 - 6e-06 26.2 0.0 0.23 11.2 0.3 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 ORY93279.1 - 0.00023 20.7 0.1 0.00079 19.0 0.1 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 ORY93279.1 - 0.009 14.9 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ORY93279.1 - 0.012 15.3 0.1 0.033 13.8 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.10 ORY93279.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) IL31 PF15209.6 ORY93279.1 - 0.045 13.5 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Interleukin 31 Lipase PF00151.19 ORY93279.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipase DLH PF01738.18 ORY93279.1 - 0.089 12.3 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family MMS1_N PF10433.9 ORY93280.1 - 4.7e-48 164.0 0.0 2e-45 155.3 0.0 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY93280.1 - 1.8e-37 129.4 0.0 4.1e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MCM PF00493.23 ORY93281.1 - 1.9e-98 328.0 0.0 2.7e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY93281.1 - 1.5e-35 121.8 1.4 2.9e-35 120.9 1.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY93281.1 - 1.5e-29 102.2 2.5 3.5e-29 101.1 2.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY93281.1 - 5.1e-14 52.7 1.9 8.7e-14 52.0 0.3 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 ORY93281.1 - 3e-08 33.8 0.0 1.3e-07 31.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY93281.1 - 8e-07 28.6 0.0 0.00094 18.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY93281.1 - 0.00019 21.3 0.1 0.013 15.4 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY93281.1 - 0.00044 20.0 0.1 1.5 8.5 0.0 3.3 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_16 PF13191.6 ORY93281.1 - 0.00058 20.3 0.4 0.0044 17.4 0.4 2.7 1 1 0 1 1 1 1 AAA ATPase domain Brr6_like_C_C PF10104.9 ORY93282.1 - 3.4e-15 56.0 1.2 3.9e-15 55.8 1.2 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain TFIIA PF03153.13 ORY93283.1 - 0.053 13.5 8.8 0.067 13.2 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YiiD_C PF09500.10 ORY93283.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) DUF4175 PF13779.6 ORY93283.1 - 3.6 5.4 13.9 4.9 4.9 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 ORY93283.1 - 5.5 6.5 16.3 8.4 5.9 16.3 1.2 1 0 0 1 1 1 0 Spt20 family Fibrillarin PF01269.17 ORY93284.1 - 1.4e-106 354.7 0.1 1.7e-106 354.4 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORY93284.1 - 4.9e-05 23.1 0.1 7.2e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORY93284.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 ORY93284.1 - 0.022 14.4 0.0 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY93284.1 - 0.04 14.0 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 ORY93284.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain ThiF PF00899.21 ORY93285.1 - 4.9e-67 225.8 0.0 6.6e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 ORY93285.1 - 3.3e-29 100.9 0.6 5.4e-29 100.2 0.6 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 ORY93285.1 - 0.00056 20.0 0.1 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 ORY93285.1 - 0.023 15.3 0.4 0.33 11.6 0.1 2.6 2 1 1 3 3 3 0 PglD N-terminal domain Pyr_redox PF00070.27 ORY93285.1 - 0.061 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 ORY93285.1 - 0.07 13.0 0.1 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Ecm33 PF12454.8 ORY93285.1 - 0.082 13.1 0.7 0.19 11.9 0.7 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_7 PF13241.6 ORY93285.1 - 0.093 13.2 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ORY93285.1 - 0.16 12.2 0.0 0.83 9.9 0.0 2.3 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Cellulase PF00150.18 ORY93286.1 - 8e-20 71.4 0.0 2.7e-13 50.0 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY93286.1 - 7.2e-18 64.9 0.3 1.8e-17 63.6 0.3 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 ORY93286.1 - 0.073 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Adap_comp_sub PF00928.21 ORY93286.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Adaptor complexes medium subunit family DUF4739 PF15893.5 ORY93286.1 - 0.24 11.0 0.9 0.37 10.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) SMYLE_N PF18615.1 ORY93287.1 - 2.3 7.7 9.4 2.7 7.5 9.4 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain bZIP_1 PF00170.21 ORY93288.1 - 1.8e-11 44.0 12.1 1.8e-11 44.0 12.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY93288.1 - 2.3e-06 27.6 12.7 2.3e-06 27.6 12.7 2.6 2 0 0 2 2 2 1 Basic region leucine zipper HALZ PF02183.18 ORY93288.1 - 0.018 15.3 1.5 0.018 15.3 1.5 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper TFIIA PF03153.13 ORY93288.1 - 0.23 11.4 40.4 0.39 10.7 40.4 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlaC_arch PF05377.11 ORY93288.1 - 0.36 11.3 1.5 0.86 10.0 1.5 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Peptidase_S64 PF08192.11 ORY93288.1 - 2.4 6.6 12.2 0.59 8.6 3.7 2.0 2 0 0 2 2 2 0 Peptidase family S64 bZIP_Maf PF03131.17 ORY93288.1 - 3.2 8.3 28.3 0.036 14.6 9.5 2.8 2 1 0 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.15 ORY93288.1 - 3.8 7.4 19.2 0.44 10.3 2.8 2.4 2 0 0 2 2 2 0 Septum formation initiator GalKase_gal_bdg PF10509.9 ORY93289.1 - 4e-24 83.9 0.0 8.1e-24 82.9 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 ORY93289.1 - 4.4e-16 59.0 0.1 2.3e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ORY93289.1 - 1.1e-15 57.5 2.4 2.8e-15 56.3 2.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Phage_antiter_Q PF06323.11 ORY93289.1 - 0.15 11.6 0.0 0.96 8.9 0.0 2.0 2 0 0 2 2 2 0 Phage antitermination protein Q bZIP_1 PF00170.21 ORY93290.1 - 4.4e-09 36.3 9.6 4.4e-09 36.3 9.6 2.1 2 1 0 2 2 1 1 bZIP transcription factor DUF1664 PF07889.12 ORY93290.1 - 0.014 15.4 0.3 0.026 14.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORY93290.1 - 0.032 14.6 0.3 0.069 13.5 0.3 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HAUS6_N PF14661.6 ORY93290.1 - 0.21 11.1 8.7 0.42 10.2 8.7 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.15 ORY93290.1 - 0.43 10.1 7.4 0.8 9.2 7.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4834 PF16118.5 ORY93290.1 - 0.56 11.2 6.6 0.44 11.5 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Adenyl_cycl_N PF12633.7 ORY93290.1 - 0.89 9.4 5.7 1.4 8.8 0.4 2.7 3 0 0 3 3 3 0 Adenylate cyclase NT domain TMF_DNA_bd PF12329.8 ORY93290.1 - 1.9 8.5 9.7 0.096 12.7 1.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding PRKG1_interact PF15898.5 ORY93290.1 - 3.7 8.5 15.8 4.6 8.2 13.7 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 ORY93290.1 - 4 6.7 9.1 8.8 5.6 9.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 ORY93290.1 - 5.6 7.0 10.4 9 6.4 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Macoilin PF09726.9 ORY93290.1 - 5.9 5.3 11.0 10 4.5 11.0 1.3 1 0 0 1 1 1 0 Macoilin family Amino_oxidase PF01593.24 ORY93292.1 - 3.9e-27 95.7 0.0 5.1e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY93292.1 - 1.1e-09 38.4 0.1 2.6e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY93292.1 - 2.1e-08 34.1 0.2 5.8e-05 22.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY93292.1 - 0.0018 18.8 0.9 0.29 11.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY93292.1 - 0.0059 15.9 0.5 0.025 13.8 0.3 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 ORY93292.1 - 0.008 16.2 0.5 0.27 11.2 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ORY93292.1 - 0.0085 15.3 0.0 0.37 10.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY93292.1 - 0.029 13.6 0.0 0.092 12.0 0.0 1.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY93292.1 - 0.079 11.8 0.3 0.29 9.9 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 ORY93292.1 - 0.11 11.9 0.4 1.4 8.1 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase MCRA PF06100.11 ORY93292.1 - 0.18 10.6 0.1 0.48 9.1 0.0 1.6 2 0 0 2 2 2 0 MCRA family dCMP_cyt_deam_1 PF00383.23 ORY93293.1 - 2.4e-16 59.5 0.0 3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ORY93293.1 - 7.2e-12 45.7 1.7 1.6e-11 44.5 0.6 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Ribophorin_I PF04597.14 ORY93294.1 - 5.2e-107 358.8 8.0 6.2e-107 358.5 8.0 1.0 1 0 0 1 1 1 1 Ribophorin I Mt_ATP-synt_B PF05405.14 ORY93295.1 - 3.7e-47 160.0 5.8 5e-47 159.5 5.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5623 PF18536.1 ORY93295.1 - 0.039 14.2 1.1 0.097 13.0 0.4 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5623) EF-hand_like PF09279.11 ORY93295.1 - 0.042 14.3 0.3 0.37 11.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like COMPASS-Shg1 PF05205.12 ORY93295.1 - 1.9 9.2 7.3 15 6.4 1.9 2.3 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 CDP-OH_P_transf PF01066.21 ORY93296.1 - 4e-17 62.8 0.1 4e-17 62.8 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cyclin PF08613.11 ORY93297.1 - 1.2e-11 45.3 1.4 1.8e-11 44.6 1.4 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY93297.1 - 9.5e-07 28.6 0.2 1.9e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain PTS_2-RNA PF01885.16 ORY93298.1 - 3.2e-69 232.6 0.0 3.7e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ribonuc_red_lgC PF02867.15 ORY93299.1 - 5.6e-188 625.7 0.0 7.1e-188 625.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ORY93299.1 - 9.8e-24 83.2 0.1 2.4e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ORY93299.1 - 2.7e-18 66.3 0.8 6.9e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain 2_5_RNA_ligase2 PF13563.6 ORY93300.1 - 0.0039 17.1 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DUF4174 PF13778.6 ORY93300.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Cu-oxidase_3 PF07732.15 ORY93301.1 - 4e-12 46.2 1.0 1.3e-11 44.6 1.0 1.9 1 1 0 1 1 1 1 Multicopper oxidase Polyketide_cyc2 PF10604.9 ORY93301.1 - 0.056 13.7 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RRM_1 PF00076.22 ORY93302.1 - 4.6e-13 48.8 0.1 7e-13 48.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 ORY93302.1 - 7.7e-09 36.2 0.1 1.6e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 ORY93302.1 - 8.7e-07 28.8 1.7 2.4e-06 27.4 1.7 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 ORY93302.1 - 0.00078 19.6 0.9 0.0018 18.5 0.4 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 ORY93302.1 - 0.0023 17.7 2.9 0.0053 16.5 2.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 ORY93302.1 - 0.0031 17.4 1.8 0.0031 17.4 1.8 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 ORY93302.1 - 0.0033 17.3 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_2 PF14608.6 ORY93302.1 - 0.0041 17.5 1.5 0.0095 16.4 1.5 1.7 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 ORY93302.1 - 0.017 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_17 PF00332.18 ORY93303.1 - 1.3e-20 74.3 0.3 1.6e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Aldedh PF00171.22 ORY93304.1 - 5e-119 397.8 0.0 5.7e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PS_Dcarbxylase PF02666.15 ORY93305.1 - 5.5e-61 205.6 0.0 8.6e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 ORY93305.1 - 9.9e-19 67.6 0.0 2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain UBZ_FAAP20 PF15750.5 ORY93305.1 - 0.082 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger Spem1 PF15670.5 ORY93305.1 - 3.9 7.0 5.2 9.8 5.7 5.2 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 MRP-S28 PF10213.9 ORY93306.1 - 1.7e-37 128.7 0.8 1.7e-37 128.7 0.8 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein GDP_Man_Dehyd PF16363.5 ORY93307.1 - 1.3e-72 245.0 0.0 1.6e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY93307.1 - 6.8e-54 182.9 0.1 8.7e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY93307.1 - 1.5e-24 86.5 0.2 1.9e-24 86.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY93307.1 - 6.8e-24 84.4 0.4 1.5e-22 80.0 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY93307.1 - 5.6e-21 74.9 0.0 3.7e-18 65.7 0.1 2.5 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY93307.1 - 3.5e-17 62.4 0.0 8.3e-17 61.2 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY93307.1 - 2.8e-06 27.4 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ORY93307.1 - 0.0094 15.4 0.1 0.06 12.8 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ORY93307.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family RibD_C PF01872.17 ORY93307.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain KR PF08659.10 ORY93307.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 KR domain ABC_tran PF00005.27 ORY93308.1 - 3.2e-48 163.7 0.3 2.2e-24 86.5 0.0 3.6 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 ORY93308.1 - 2.8e-15 56.9 0.4 0.0011 18.9 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY93308.1 - 1.5e-14 54.0 1.9 0.0028 17.1 0.0 4.5 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain Chromo PF00385.24 ORY93308.1 - 5.7e-11 42.2 0.5 1.2e-10 41.1 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 ORY93308.1 - 2.4e-08 34.7 1.0 0.0054 17.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ORY93308.1 - 1.3e-07 32.0 0.1 0.005 17.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 ORY93308.1 - 3.8e-07 29.7 0.2 0.033 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY93308.1 - 3.5e-06 27.0 0.1 0.057 13.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 ORY93308.1 - 2.8e-05 24.3 7.3 0.035 14.3 0.0 3.9 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 ORY93308.1 - 3.6e-05 23.8 0.0 0.19 11.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY93308.1 - 3.8e-05 24.1 0.1 0.32 11.4 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 ORY93308.1 - 0.00021 21.1 0.0 1 9.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 ORY93308.1 - 0.00032 21.0 0.0 2.1 8.8 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 ORY93308.1 - 0.00049 20.6 0.0 3.8 8.1 0.0 3.8 4 0 0 4 4 3 1 AAA domain CLASP_N PF12348.8 ORY93308.1 - 0.00052 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 CLASP N terminal AAA_15 PF13175.6 ORY93308.1 - 0.0011 18.7 0.4 1.8 8.2 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain Adaptin_N PF01602.20 ORY93308.1 - 0.0015 17.2 0.0 0.071 11.7 0.0 2.2 1 1 1 2 2 2 1 Adaptin N terminal region AAA_28 PF13521.6 ORY93308.1 - 0.0016 18.7 0.0 0.59 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY93308.1 - 0.0023 18.3 0.0 6.9 7.1 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORY93308.1 - 0.0026 17.0 0.8 0.065 12.4 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 ORY93308.1 - 0.0027 17.6 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_27 PF13514.6 ORY93308.1 - 0.0031 17.1 2.0 1.2 8.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 ORY93308.1 - 0.004 16.2 0.4 2.2 7.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 ORY93308.1 - 0.0064 16.2 0.1 3.1 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY93308.1 - 0.0071 15.9 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 ORY93308.1 - 0.0071 16.4 0.0 3.2 7.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY93308.1 - 0.0084 16.0 0.1 0.48 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Cytidylate_kin PF02224.18 ORY93308.1 - 0.012 15.4 0.0 1.7 8.3 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 ORY93308.1 - 0.012 15.5 0.1 6.6 6.6 0.0 2.8 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 ORY93308.1 - 0.021 14.9 0.0 0.56 10.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 ORY93308.1 - 0.024 14.9 0.0 2 8.7 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit HEAT_EZ PF13513.6 ORY93308.1 - 0.031 14.8 0.2 7.4 7.2 0.0 4.1 4 0 0 4 4 3 0 HEAT-like repeat ATP_bind_1 PF03029.17 ORY93308.1 - 0.044 13.6 0.3 7.9 6.2 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 ORY93308.1 - 0.045 14.0 0.2 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Vac14_Fab1_bd PF12755.7 ORY93308.1 - 0.055 14.1 0.0 40 4.9 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region cobW PF02492.19 ORY93308.1 - 0.067 12.8 0.1 6.6 6.3 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ORY93308.1 - 0.078 12.3 0.1 3.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 ORY93308.1 - 0.088 12.7 0.0 2.4 8.0 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 ORY93308.1 - 0.11 11.8 0.0 9.9 5.3 0.0 2.4 2 0 0 2 2 2 0 Septin DUF87 PF01935.17 ORY93308.1 - 0.11 12.6 6.6 1.2 9.1 0.1 3.9 5 0 0 5 5 4 0 Helicase HerA, central domain DUF815 PF05673.13 ORY93308.1 - 0.12 11.5 0.0 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PIN7 PF18475.1 ORY93308.1 - 0.13 12.9 0.0 0.36 11.5 0.0 1.7 1 0 0 1 1 1 0 PIN domain TsaE PF02367.17 ORY93308.1 - 0.14 12.2 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MADF_DNA_bdg PF10545.9 ORY93308.1 - 3 8.2 7.1 1.7 9.0 0.3 2.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_13 PF13166.6 ORY93308.1 - 4.1 5.9 5.2 4.8 5.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain BAR PF03114.18 ORY93309.1 - 3.4e-46 157.8 2.8 4.4e-46 157.5 2.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORY93309.1 - 7.2e-06 25.9 0.7 1e-05 25.4 0.7 1.2 1 0 0 1 1 1 1 BAR domain of APPL family AAA_13 PF13166.6 ORY93309.1 - 0.00041 19.1 1.2 0.00055 18.7 1.2 1.2 1 0 0 1 1 1 1 AAA domain Arfaptin PF06456.13 ORY93309.1 - 0.00067 19.3 4.7 0.0026 17.4 4.7 2.0 1 1 0 1 1 1 1 Arfaptin-like domain OrfB_IS605 PF01385.19 ORY93309.1 - 0.0016 18.7 0.8 0.22 11.7 0.1 2.3 2 0 0 2 2 2 2 Probable transposase Occludin_ELL PF07303.13 ORY93309.1 - 0.068 13.9 3.9 0.068 13.9 1.4 2.2 2 0 0 2 2 2 0 Occludin homology domain GerPC PF10737.9 ORY93309.1 - 0.21 11.6 3.3 14 5.7 0.0 2.8 2 1 1 3 3 3 0 Spore germination protein GerPC TANGO2 PF05742.12 ORY93310.1 - 2.9e-18 66.9 0.0 3.4e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Methyltransf_4 PF02390.17 ORY93311.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF2878 PF11086.8 ORY93313.1 - 0.0037 17.5 2.3 0.0056 16.9 2.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2878) Ligase_CoA PF00549.19 ORY93313.1 - 0.013 15.4 0.0 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 CoA-ligase stn_TNFRSF12A PF12191.8 ORY93313.1 - 0.032 14.4 0.1 1.8 8.8 0.0 2.0 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain UL45 PF05473.12 ORY93313.1 - 0.61 9.7 4.3 5.5 6.6 0.4 2.1 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like AMP-binding PF00501.28 ORY93317.1 - 1.3e-63 215.1 0.5 2.1e-35 122.1 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ORY93317.1 - 1.1e-07 32.7 0.4 3.4e-07 31.1 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sof1 PF04158.14 ORY93318.1 - 3.1e-29 101.1 12.8 5.8e-29 100.2 12.8 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 ORY93318.1 - 3.4e-26 91.0 10.1 6.2e-05 23.7 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.11 ORY93318.1 - 3.4e-05 23.8 0.7 0.00096 19.1 0.1 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 ORY93318.1 - 8.4e-05 22.8 0.0 1.1 9.6 0.0 4.5 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY93318.1 - 0.051 12.9 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain DUF4594 PF15266.6 ORY93318.1 - 3.6 7.9 11.7 0.087 13.2 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4594) RRM_1 PF00076.22 ORY93319.1 - 7e-06 25.8 0.4 1.4e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 ORY93319.1 - 7.8e-06 25.7 2.5 1.2e-05 25.1 2.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY93319.1 - 0.0017 18.3 1.0 0.0028 17.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 ORY93319.1 - 0.012 16.2 0.1 0.049 14.3 0.1 2.1 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 ORY93319.1 - 0.018 14.8 3.9 0.029 14.2 3.9 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger Nup35_RRM_2 PF14605.6 ORY93319.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1_like PF12832.7 ORY93320.1 - 7.3e-63 212.7 9.6 9.1e-63 212.4 9.6 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 ORY93320.1 - 2.6e-18 66.1 47.6 3.3e-13 49.3 20.2 3.6 1 1 0 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 ORY93320.1 - 1.6e-08 34.0 5.2 1.6e-08 34.0 5.2 2.4 2 1 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 ORY93320.1 - 0.00029 19.7 6.5 0.00029 19.7 6.5 2.3 3 0 0 3 3 3 1 LacY proton/sugar symporter OATP PF03137.20 ORY93320.1 - 1.1 7.5 9.9 0.048 12.0 3.6 2.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RAP1 PF07218.11 ORY93321.1 - 7.1 4.8 7.3 9.9 4.3 7.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GrpE PF01025.19 ORY93322.1 - 3.4e-47 160.2 5.3 5.2e-47 159.6 5.3 1.3 1 0 0 1 1 1 1 GrpE PRP38 PF03371.15 ORY93322.1 - 0.019 14.9 0.2 0.031 14.1 0.2 1.3 1 0 0 1 1 1 0 PRP38 family Phage_tail_S PF05069.13 ORY93322.1 - 0.076 12.9 0.1 0.076 12.9 0.1 2.0 2 0 0 2 2 2 0 Phage virion morphogenesis family DUF334 PF03904.13 ORY93322.1 - 0.2 11.1 3.6 0.25 10.8 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Mit_KHE1 PF10173.9 ORY93322.1 - 1.5 8.9 3.5 2.8 8.0 3.5 1.5 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Reprolysin_4 PF13583.6 ORY93323.1 - 2.8e-47 161.0 0.7 5.1e-47 160.1 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY93323.1 - 6.5e-46 157.0 6.0 6.5e-46 157.0 6.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORY93323.1 - 5.8e-44 150.3 1.3 1.1e-43 149.4 1.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 ORY93323.1 - 1.6e-14 54.4 0.0 3.9e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 ORY93323.1 - 4e-14 53.2 26.3 4e-14 53.2 26.3 4.1 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.19 ORY93323.1 - 3.4e-06 27.3 0.0 9.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 ORY93323.1 - 9.8e-05 22.3 8.6 0.0014 18.6 8.6 2.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease PDH PF02153.17 ORY93324.1 - 2.9e-16 59.3 0.0 3.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 ORY93324.1 - 1.3e-06 28.9 0.0 2.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ORY93324.1 - 4.8e-05 23.1 0.0 0.00014 21.5 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 ORY93324.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ORY93324.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PglD_N PF17836.1 ORY93324.1 - 0.011 16.4 0.0 0.03 15.0 0.0 1.8 1 0 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 ORY93324.1 - 0.03 14.6 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 ORY93324.1 - 0.065 12.6 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 ORY93324.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CTNNBL PF08216.11 ORY93325.1 - 9e-39 131.8 1.0 9e-39 131.8 1.0 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 ORY93325.1 - 0.048 13.7 0.4 5.1 7.3 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat YolD PF08863.10 ORY93325.1 - 1.1 9.4 8.7 2.6 8.2 0.3 2.8 2 0 0 2 2 2 0 YolD-like protein UPF0184 PF03670.13 ORY93325.1 - 3.8 8.0 9.1 0.32 11.4 0.2 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) GST_N_3 PF13417.6 ORY93326.1 - 2.3e-12 47.1 0.0 4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY93326.1 - 1.5e-09 38.0 0.0 2.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY93326.1 - 1.4e-08 34.9 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY93326.1 - 2.1e-07 31.2 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY93326.1 - 3.9e-07 30.0 0.0 7.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY93326.1 - 1.2e-06 28.3 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_3 PF14497.6 ORY93326.1 - 6.8e-06 26.2 0.0 2e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORY93326.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Endostatin PF06482.11 ORY93326.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Glyco_hydro_43 PF04616.14 ORY93327.1 - 8.1e-69 232.1 0.3 2.2e-68 230.7 0.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORY93327.1 - 5.1e-18 65.5 0.0 1.3e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain T2SSG PF08334.11 ORY93327.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Sugar_tr PF00083.24 ORY93328.1 - 6.7e-100 335.1 27.8 7.8e-100 334.8 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY93328.1 - 2.8e-36 125.2 18.4 2.8e-36 125.2 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YL1 PF05764.13 ORY93329.1 - 9e-42 143.9 38.3 1.2e-41 143.4 38.3 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 ORY93329.1 - 8.5e-15 54.2 0.0 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_25 PF13649.6 ORY93330.1 - 1.3e-14 54.6 0.1 3.7e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY93330.1 - 2.2e-12 47.5 0.0 7.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY93330.1 - 4.6e-12 46.0 0.0 7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY93330.1 - 1.4e-11 44.3 0.0 1.9e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ORY93330.1 - 4.7e-08 33.1 0.0 1.3e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY93330.1 - 4.6e-07 29.1 0.0 6.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 ORY93330.1 - 1.3e-06 29.0 0.0 2.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY93330.1 - 7.5e-06 25.4 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORY93330.1 - 9.7e-06 25.2 0.2 1.6e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 ORY93330.1 - 2.9e-05 24.0 0.2 4.9e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 ORY93330.1 - 0.00052 19.9 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TehB PF03848.14 ORY93330.1 - 0.00053 19.5 1.8 0.0022 17.4 0.6 2.3 2 1 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 ORY93330.1 - 0.002 18.1 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ORY93330.1 - 0.0027 18.7 0.0 0.0056 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY93330.1 - 0.0037 17.4 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 ORY93330.1 - 0.0056 16.0 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 ORY93330.1 - 0.019 14.7 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 ORY93330.1 - 0.065 13.0 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 ORY93330.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DOT1 PF08123.13 ORY93330.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Hexokinase_2 PF03727.16 ORY93331.1 - 3e-83 278.9 0.0 4.1e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY93331.1 - 2.3e-71 239.8 0.0 3.3e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Aminotran_1_2 PF00155.21 ORY93332.1 - 4.3e-14 52.5 0.0 5.2e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 ORY93333.1 - 0.018 14.2 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II Cyclase PF04199.13 ORY93334.1 - 1.4e-14 54.5 0.0 1.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase T5orf172 PF10544.9 ORY93335.1 - 1.6e-18 67.1 0.2 3.1e-18 66.2 0.2 1.4 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ORY93335.1 - 3.3e-12 46.9 0.4 6.4e-12 46.0 0.4 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Fungal_trans PF04082.18 ORY93336.1 - 0.01 14.9 0.1 0.022 13.8 0.1 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3939 PF13075.6 ORY93337.1 - 0.27 11.3 2.4 0.2 11.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) PepSY_TM PF03929.16 ORY93338.1 - 0.019 14.7 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region FixQ PF05545.11 ORY93338.1 - 0.057 13.4 0.2 0.095 12.7 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ zf-UBP PF02148.19 ORY93339.1 - 4.7e-16 58.9 13.1 6.1e-16 58.5 13.1 1.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein ArfGap PF01412.18 ORY93339.1 - 0.34 11.0 8.4 0.089 12.9 5.5 1.4 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf zf-HIT PF04438.16 ORY93339.1 - 1.5 8.7 7.7 0.11 12.4 2.0 2.0 2 0 0 2 2 2 0 HIT zinc finger zf-B_box PF00643.24 ORY93339.1 - 3.5 7.9 14.1 10 6.3 9.0 2.5 1 1 1 2 2 2 0 B-box zinc finger Ras PF00071.22 ORY93340.1 - 1.5e-59 200.2 0.7 1.8e-59 200.0 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY93340.1 - 6.2e-35 120.0 0.2 9.1e-35 119.5 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY93340.1 - 8.5e-14 51.4 0.1 1.1e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY93340.1 - 9.2e-07 28.9 0.1 1.5e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY93340.1 - 3.4e-05 23.8 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY93340.1 - 0.00024 20.7 0.3 0.0031 17.1 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY93340.1 - 0.0014 19.0 0.0 0.0071 16.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 ORY93340.1 - 0.0036 16.7 0.1 0.0048 16.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORY93340.1 - 0.0069 15.8 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 ORY93340.1 - 0.021 14.8 0.1 0.034 14.1 0.1 1.4 1 1 0 1 1 1 0 NTPase AAA_14 PF13173.6 ORY93340.1 - 0.028 14.4 0.1 0.14 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY93340.1 - 0.03 14.0 0.1 0.064 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY93340.1 - 0.041 14.4 0.4 0.072 13.6 0.4 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 ORY93340.1 - 0.056 13.8 0.1 0.094 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 ORY93340.1 - 0.078 13.2 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ORY93340.1 - 0.12 11.7 0.1 0.25 10.6 0.1 1.5 1 0 0 1 1 1 0 Septin TniB PF05621.11 ORY93340.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 ORY93340.1 - 0.14 11.9 0.0 0.81 9.4 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AATase PF07247.12 ORY93341.1 - 9.8e-10 37.6 0.0 1.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase tRNA-synt_1 PF00133.22 ORY93342.1 - 3.9e-60 203.8 0.1 8.5e-20 70.5 0.3 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 ORY93342.1 - 4e-54 183.0 0.0 6.7e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 ORY93342.1 - 3e-26 92.1 2.7 2.9e-18 65.8 0.0 4.3 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORY93342.1 - 9.4e-18 64.6 0.1 2.7e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORY93342.1 - 0.0023 17.3 0.0 0.34 10.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain GCN5L1 PF06320.13 ORY93342.1 - 0.051 13.7 3.3 0.21 11.8 0.8 2.5 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Acyl-CoA_dh_1 PF00441.24 ORY93343.1 - 1.4e-31 109.7 0.1 2.5e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY93343.1 - 1.8e-20 72.9 0.0 4e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY93343.1 - 1.3e-18 67.0 0.4 2.4e-18 66.1 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY93343.1 - 1.1e-09 39.0 0.0 3.4e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY93343.1 - 0.00041 20.6 0.1 0.0066 16.7 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY93343.1 - 0.017 14.8 0.1 1.4 8.5 0.0 2.6 2 1 1 3 3 3 0 4-hydroxyphenylacetate 3-hydroxylase N terminal SAM_1 PF00536.30 ORY93343.1 - 0.21 12.1 0.2 21 5.6 0.0 2.8 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Bax1-I PF01027.20 ORY93344.1 - 6.3e-52 176.4 27.6 7.3e-52 176.2 27.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Polysacc_synt_C PF14667.6 ORY93344.1 - 2.1 8.4 19.6 0.68 10.0 8.1 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain CPP1-like PF11833.8 ORY93344.1 - 2.9 7.5 11.0 0.3 10.7 2.7 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SLX9 PF15341.6 ORY93345.1 - 9.9e-20 71.3 10.9 9.9e-20 71.3 10.9 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DEC-1_N PF04625.13 ORY93346.1 - 0.34 9.9 4.5 0.44 9.5 4.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region p450 PF00067.22 ORY93347.1 - 1e-41 143.2 0.0 1.4e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Alk_phosphatase PF00245.20 ORY93348.1 - 9.4e-62 209.3 0.1 1.3e-61 208.8 0.1 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 ORY93348.1 - 1.9e-05 24.3 1.0 0.00065 19.2 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 ORY93348.1 - 8.6e-05 22.3 1.1 0.00034 20.3 0.1 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase MBG_2 PF18676.1 ORY93348.1 - 2.1 9.0 6.5 23 5.7 1.0 3.7 2 1 0 2 2 2 0 MBG domain (YGX type) PsbR PF04725.12 ORY93350.1 - 0.053 13.9 0.2 0.072 13.4 0.2 1.3 1 1 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR UCH PF00443.29 ORY93351.1 - 5.8e-55 186.6 0.1 1.2e-54 185.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY93351.1 - 6.3e-23 81.9 0.0 6.3e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORY93351.1 - 7.6e-05 22.3 1.8 0.0072 15.8 0.5 2.8 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF5386 PF17360.2 ORY93351.1 - 0.97 9.3 5.0 0.18 11.7 1.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5386) SR-25 PF10500.9 ORY93352.1 - 0.55 9.8 66.0 0.023 14.3 56.9 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.13 ORY93352.1 - 1.6 8.6 30.0 0.3 11.0 23.4 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Prominin PF05478.11 ORY93355.1 - 0.21 9.5 0.4 0.24 9.3 0.4 1.0 1 0 0 1 1 1 0 Prominin Vps54 PF07928.12 ORY93356.1 - 3.8e-51 173.0 2.4 5e-51 172.7 0.0 2.5 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 ORY93356.1 - 2.8e-11 43.2 0.2 2.8e-11 43.2 0.2 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 ORY93356.1 - 1.4e-05 24.2 0.0 4.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF2451 PF10474.9 ORY93356.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2451) DUF4363 PF14276.6 ORY93356.1 - 4.2 7.5 7.0 21 5.3 0.0 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4363) COG5 PF10392.9 ORY93356.1 - 9.5 6.4 8.7 2.5 8.3 4.4 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 MFS_1 PF07690.16 ORY93357.1 - 7.7e-38 130.3 28.3 1.2e-37 129.6 28.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 ORY93357.1 - 0.14 10.9 15.0 0.26 10.0 3.3 2.3 2 1 0 2 2 2 0 LacY proton/sugar symporter MFS_1_like PF12832.7 ORY93357.1 - 0.85 8.4 12.2 0.15 10.9 2.3 2.2 2 0 0 2 2 2 0 MFS_1 like family eRF1_2 PF03464.15 ORY93358.1 - 9.1e-46 155.5 0.1 1.4e-45 154.9 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORY93358.1 - 6.4e-37 126.5 0.0 1.2e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 ORY93358.1 - 7e-18 64.9 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 ORY93358.1 - 8.5e-10 39.0 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 ORY93358.1 - 3.1e-08 34.0 0.1 4.7e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor MDM10 PF12519.8 ORY93359.1 - 5.7e-93 312.3 2.3 3.3e-84 283.4 1.2 2.3 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 ORY93359.1 - 0.0039 16.7 0.0 0.021 14.3 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic porin Voltage_CLC PF00654.20 ORY93360.1 - 2e-86 290.4 23.4 2e-86 290.4 23.4 2.1 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY93360.1 - 3.6e-05 24.1 0.0 0.00033 21.0 0.0 2.6 3 0 0 3 3 3 1 CBS domain Bac_export_2 PF01312.19 ORY93360.1 - 0.15 11.2 6.6 0.22 10.7 0.0 2.9 2 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family TAT_signal PF10518.9 ORY93360.1 - 0.56 10.1 7.8 0.08 12.8 0.9 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Gti1_Pac2 PF09729.9 ORY93361.1 - 2.2e-59 200.6 1.1 2.6e-59 200.4 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family Pam16 PF03656.13 ORY93362.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Pam16 Ribosomal_60s PF00428.19 ORY93362.1 - 3.5 8.3 10.3 11 6.7 10.3 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tubulin PF00091.25 ORY93363.1 - 1.2e-67 227.9 0.0 1.7e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY93363.1 - 2.4e-50 169.9 0.0 4e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY93363.1 - 0.00034 20.3 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MFS_1_like PF12832.7 ORY93364.1 - 1.9e-56 191.6 17.5 2.5e-56 191.2 17.5 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 ORY93364.1 - 3.5e-13 49.2 49.2 7.4e-08 31.7 5.3 3.1 1 1 0 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 ORY93364.1 - 3e-06 26.5 10.2 3e-06 26.5 10.2 2.5 2 1 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 ORY93364.1 - 6.4e-05 21.9 17.0 0.00055 18.8 17.0 2.4 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 ORY93364.1 - 0.00044 18.9 10.3 0.00044 18.9 10.3 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein DUF3292 PF11696.8 ORY93364.1 - 0.16 10.3 0.4 0.25 9.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) 14-3-3 PF00244.20 ORY93365.1 - 6.7e-95 316.8 1.8 7.5e-95 316.6 1.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 ORY93365.1 - 0.24 11.9 1.9 0.52 10.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5588 PF17826.1 ORY93366.1 - 0.08 11.8 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) IucA_IucC PF04183.12 ORY93367.1 - 2.7e-25 89.3 0.0 4.6e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 ORY93367.1 - 2.6e-10 41.0 0.0 4.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IlvN PF07991.12 ORY93368.1 - 1.5e-45 154.7 0.0 2.4e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORY93368.1 - 1e-42 145.8 0.0 1.7e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 ORY93368.1 - 0.0084 16.7 0.0 0.038 14.6 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORY93368.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ORY93368.1 - 0.088 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TPP_enzyme_N PF02776.18 ORY93369.1 - 2.8e-56 189.8 0.1 8e-56 188.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORY93369.1 - 6.8e-52 175.3 0.2 2.9e-50 170.0 0.1 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY93369.1 - 2.1e-38 131.1 0.4 4.9e-38 130.0 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ORY93369.1 - 0.055 13.2 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DDOST_48kD PF03345.14 ORY93370.1 - 1.6e-121 406.0 0.3 4.8e-121 404.5 0.3 1.6 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Myb_DNA-bind_2 PF08914.11 ORY93370.1 - 0.0049 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Rap1 Myb domain DUF5640 PF18692.1 ORY93370.1 - 0.082 12.9 1.1 0.15 12.1 0.0 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5640) EamA PF00892.20 ORY93371.1 - 6.1e-13 49.1 33.3 6.2e-07 29.7 9.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORY93371.1 - 3.1e-06 26.7 0.2 5.1e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 ORY93371.1 - 6.7e-06 25.8 7.8 5.4e-05 22.8 7.9 2.2 1 1 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 ORY93371.1 - 1.6e-05 24.3 0.0 1.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 ORY93371.1 - 0.037 13.4 0.4 0.037 13.4 0.4 2.3 2 1 0 2 2 2 0 Triose-phosphate Transporter family Pho86 PF11124.8 ORY93371.1 - 1.7 8.1 4.5 0.43 10.0 1.3 1.5 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 HIG_1_N PF04588.13 ORY93372.1 - 3.4e-20 72.0 2.0 1.6e-19 69.9 0.9 2.2 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF533 PF04391.12 ORY93372.1 - 0.0049 16.5 0.2 0.007 16.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF533) DUF5423 PF17461.2 ORY93372.1 - 0.052 12.4 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Homeodomain PF00046.29 ORY93373.1 - 2.3e-22 78.6 2.1 5.1e-22 77.5 2.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY93373.1 - 0.0021 17.9 0.5 0.024 14.5 0.1 2.7 2 0 0 2 2 2 1 Homeobox KN domain Pkinase PF00069.25 ORY93374.1 - 2e-63 214.2 0.0 2.7e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93374.1 - 4.5e-32 111.4 0.0 6e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY93374.1 - 2.2e-06 27.2 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY93374.1 - 0.0021 18.0 0.2 0.0036 17.3 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY93374.1 - 0.0051 15.6 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY93374.1 - 0.016 14.6 0.4 0.03 13.7 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_10 PF05176.14 ORY93375.1 - 2.6e-56 190.7 0.3 3.1e-56 190.5 0.3 1.0 1 0 0 1 1 1 1 ATP10 protein TMF_DNA_bd PF12329.8 ORY93376.1 - 1.2e-16 60.4 13.2 1.2e-16 60.4 13.2 4.8 4 1 0 4 4 4 2 TATA element modulatory factor 1 DNA binding SUIM_assoc PF16619.5 ORY93376.1 - 0.011 15.7 4.1 0.011 15.7 4.1 3.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1910 PF08928.10 ORY93376.1 - 0.059 13.4 0.1 0.059 13.4 0.1 3.5 3 1 0 4 4 4 0 Domain of unknown function (DUF1910) AHSP PF09236.10 ORY93376.1 - 0.41 11.1 0.1 0.41 11.1 0.1 4.2 5 0 0 5 5 5 0 Alpha-haemoglobin stabilising protein RabGAP-TBC PF00566.18 ORY93377.1 - 4.5e-07 29.7 2.0 8e-07 28.9 2.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Gpi16 PF04113.14 ORY93378.1 - 3.7e-172 573.7 0.1 6.2e-171 569.6 0.1 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component BCDHK_Adom3 PF10436.9 ORY93379.1 - 4.1e-65 218.6 0.0 6.8e-65 217.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY93379.1 - 6.4e-13 49.2 0.0 1.1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY93379.1 - 0.003 17.4 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mo25 PF08569.11 ORY93380.1 - 3.3e-141 470.4 17.0 3.9e-141 470.2 17.0 1.0 1 0 0 1 1 1 1 Mo25-like Lipocalin_7 PF14651.6 ORY93380.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family CPSase_L_D2 PF02786.17 ORY93381.1 - 2.1e-75 252.9 0.0 5.5e-75 251.5 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY93381.1 - 3.5e-39 133.7 0.5 3.4e-38 130.6 0.1 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY93381.1 - 1.3e-32 112.1 0.0 3.9e-31 107.3 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY93381.1 - 1e-16 60.5 2.2 2.3e-16 59.4 2.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 ORY93381.1 - 4.5e-12 46.4 0.1 1.4e-11 44.9 0.1 1.9 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 ORY93381.1 - 3.7e-11 42.9 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY93381.1 - 6.9e-08 32.2 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY93381.1 - 0.00065 19.5 5.9 0.024 14.5 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 ORY93381.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 ORY93381.1 - 0.0032 17.4 0.3 0.012 15.5 0.3 2.0 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 ORY93381.1 - 0.0085 15.3 1.2 0.6 9.3 0.1 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 ORY93381.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein PK_C PF02887.16 ORY93381.1 - 0.089 13.0 0.4 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain HlyD_3 PF13437.6 ORY93381.1 - 0.16 12.7 2.9 15 6.4 0.1 3.1 3 0 0 3 3 2 0 HlyD family secretion protein Ribosomal_S19 PF00203.21 ORY93382.1 - 3e-26 91.1 0.0 3.7e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Lectin_leg-like PF03388.13 ORY93383.1 - 5.1e-71 238.7 0.1 7.4e-71 238.1 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 ORY93383.1 - 2.7e-11 43.9 0.9 3.8e-11 43.4 0.9 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 ORY93383.1 - 1.9e-08 34.1 0.0 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain Septin PF00735.18 ORY93384.1 - 2.1e-111 371.7 0.1 3.3e-111 371.1 0.1 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 ORY93384.1 - 7.5e-08 32.5 0.4 1.4e-06 28.3 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY93384.1 - 2.1e-07 30.7 1.5 3.4e-05 23.5 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY93384.1 - 1.1e-06 28.7 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ORY93384.1 - 9.1e-05 22.7 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 ORY93384.1 - 0.0017 18.9 5.7 0.18 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY93384.1 - 0.002 18.4 0.6 0.0048 17.2 0.1 2.0 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY93384.1 - 0.0066 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.16 ORY93384.1 - 0.0069 15.7 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 ORY93384.1 - 0.0079 15.8 0.1 0.02 14.5 0.1 1.7 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 ORY93384.1 - 0.008 16.6 0.3 0.027 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 ORY93384.1 - 0.013 15.9 0.1 0.045 14.1 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 ORY93384.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 ORY93384.1 - 0.016 14.7 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 ORY93384.1 - 0.017 14.7 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ORY93384.1 - 0.038 14.1 1.6 0.17 12.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 ORY93384.1 - 0.043 13.6 0.7 0.76 9.5 0.2 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 ORY93384.1 - 0.044 13.5 3.6 0.055 13.2 0.3 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY93384.1 - 0.048 14.2 0.4 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.13 ORY93384.1 - 0.058 12.4 0.3 0.13 11.3 0.2 1.6 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 ORY93384.1 - 0.064 13.3 6.7 1.3 9.1 0.0 3.1 2 1 1 3 3 3 0 Dynamin family IstB_IS21 PF01695.17 ORY93384.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 ORY93384.1 - 0.11 13.0 0.1 0.68 10.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Exonuc_VII_L PF02601.15 ORY93384.1 - 0.11 12.0 0.9 0.16 11.5 0.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PduV-EutP PF10662.9 ORY93384.1 - 0.12 12.1 0.5 9.1 6.0 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 ORY93384.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Gtr1_RagA PF04670.12 ORY93384.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Mei5 PF10376.9 ORY93384.1 - 0.23 11.3 10.1 0.087 12.7 4.3 2.1 2 0 0 2 2 2 0 Double-strand recombination repair protein DUF4407 PF14362.6 ORY93384.1 - 0.52 9.6 2.4 1.1 8.5 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 ORY93384.1 - 0.57 10.7 12.5 0.14 12.7 8.8 1.8 2 0 0 2 2 1 0 Apg6 coiled-coil region F-box-like PF12937.7 ORY93385.1 - 0.0027 17.6 0.5 0.018 15.0 0.0 2.6 2 0 0 2 2 2 1 F-box-like Cyanate_lyase PF02560.14 ORY93386.1 - 1.3e-36 124.3 0.0 1.9e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 ORY93386.1 - 8.6e-05 22.5 0.0 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 ORY93386.1 - 0.0069 16.7 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ORY93386.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain UBX PF00789.20 ORY93387.1 - 6.4e-17 61.5 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 ORY93387.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.26 ORY93387.1 - 0.12 12.9 1.2 0.25 11.9 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Hamartin PF04388.12 ORY93387.1 - 0.32 9.6 16.2 0.37 9.4 16.2 1.0 1 0 0 1 1 1 0 Hamartin protein RskA PF10099.9 ORY93387.1 - 4.4 7.6 14.3 0.084 13.2 6.3 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SAPS PF04499.15 ORY93387.1 - 4.9 5.8 14.1 5.8 5.6 14.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AdoMet_MTase PF07757.13 ORY93388.1 - 9.8e-37 125.7 0.1 1.7e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_11 PF08241.12 ORY93388.1 - 0.0062 17.2 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY93388.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1857 PF08982.11 ORY93388.1 - 0.0094 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Methyltransf_32 PF13679.6 ORY93388.1 - 0.015 15.3 0.4 0.096 12.7 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain MetW PF07021.12 ORY93388.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 ORY93388.1 - 0.025 15.3 0.0 0.05 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORY93388.1 - 0.042 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyoxalase_6 PF18029.1 ORY93388.1 - 0.05 14.4 0.3 0.19 12.6 0.0 2.0 3 0 0 3 3 3 0 Glyoxalase-like domain MTS PF05175.14 ORY93388.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Abhydrolase_3 PF07859.13 ORY93389.1 - 1.4e-60 204.8 0.0 1.6e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY93389.1 - 5e-06 25.6 0.0 8.2e-06 24.9 0.0 1.4 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY93389.1 - 7.1e-06 25.2 0.0 3.9e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORY93389.1 - 4e-05 23.2 0.0 8.2e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family HEAT_EZ PF13513.6 ORY93390.1 - 1e-25 89.8 9.1 5.9e-07 29.9 0.0 10.2 7 1 2 9 9 9 4 HEAT-like repeat HEAT PF02985.22 ORY93390.1 - 9e-25 84.6 12.1 0.00053 20.0 0.0 11.4 11 0 0 11 11 10 5 HEAT repeat HEAT_2 PF13646.6 ORY93390.1 - 1.2e-20 73.7 3.2 6.8e-06 26.4 0.0 8.4 5 2 3 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 ORY93390.1 - 2.5e-12 47.2 1.0 0.13 12.9 0.0 7.4 6 1 1 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY93390.1 - 6.4e-12 45.8 3.2 1.1e-05 25.6 0.1 5.1 4 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 ORY93390.1 - 1.4e-07 31.0 0.1 9.7e-05 21.6 0.0 4.7 3 2 2 6 6 6 1 RNAPII transcription regulator C-terminal IBN_N PF03810.19 ORY93390.1 - 2.3e-07 30.6 2.0 4.5e-07 29.7 0.2 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 ORY93390.1 - 3.1e-07 29.3 0.8 0.00051 18.7 0.1 3.4 3 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 ORY93390.1 - 5.1e-06 26.2 0.0 0.11 12.0 0.0 4.1 4 0 0 4 4 4 2 CLASP N terminal RIX1 PF08167.12 ORY93390.1 - 0.00012 21.9 0.1 0.28 10.9 0.0 4.8 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis ParcG PF10274.9 ORY93390.1 - 0.00037 20.7 0.0 0.021 14.9 0.0 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein Tti2 PF10521.9 ORY93390.1 - 0.0013 18.3 0.1 0.2 11.2 0.0 3.5 4 0 0 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 ORY93390.1 - 0.013 15.6 0.0 0.54 10.5 0.0 3.8 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 ORY93390.1 - 0.15 12.2 10.8 51 4.1 0.0 6.7 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat RasGEF PF00617.19 ORY93391.1 - 2.6e-49 167.8 0.7 5.9e-49 166.7 0.7 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY93391.1 - 2.5e-11 43.7 0.0 1.2e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 ORY93391.1 - 9.6e-05 22.0 0.0 0.00028 20.5 0.0 1.8 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 ORY93391.1 - 0.0035 17.7 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 ORY93391.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_14 PF13173.6 ORY93391.1 - 0.027 14.5 0.0 0.083 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY93391.1 - 0.18 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DIM1 PF02966.16 ORY93392.1 - 4.8e-68 227.0 0.3 5.4e-68 226.9 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 ORY93392.1 - 3.9e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY93392.1 - 0.0093 16.3 0.4 0.016 15.5 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 ORY93392.1 - 0.04 14.1 0.0 0.079 13.2 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredox_DsbH PF03190.15 ORY93393.1 - 1.3e-76 256.1 0.0 2.6e-76 255.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 ORY93393.1 - 1e-11 44.9 0.0 2.2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY93393.1 - 0.0058 17.1 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_88 PF07470.13 ORY93393.1 - 0.017 14.2 0.2 1.7 7.6 0.0 2.5 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 ORY93393.1 - 0.024 14.2 0.3 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 ORY93393.1 - 0.051 12.8 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 ORY93393.1 - 0.081 11.4 0.8 7.2 5.0 0.0 2.4 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Nup214_FG PF18617.1 ORY93393.1 - 0.31 11.6 2.6 0.63 10.6 2.6 1.5 1 0 0 1 1 1 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain SAP30_Sin3_bdg PF13867.6 ORY93393.1 - 0.86 10.0 2.6 3.9 7.9 0.1 2.9 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4199 PF13858.6 ORY93394.1 - 0.00032 21.1 7.8 0.0055 17.1 0.2 3.6 1 1 2 3 3 3 1 Protein of unknown function (DUF4199) DUF2561 PF10812.8 ORY93394.1 - 0.035 14.1 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) FUSC PF04632.12 ORY93394.1 - 0.87 8.0 6.0 1.8 7.0 2.9 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family SUI1 PF01253.22 ORY93395.1 - 1.8e-24 86.0 0.2 2.3e-24 85.7 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 PBP PF01161.20 ORY93396.1 - 1.9e-17 63.8 0.1 2.1e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.18 ORY93397.1 - 8.1e-06 25.9 13.3 8.1e-06 25.9 13.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Jnk-SapK_ap_N PF09744.9 ORY93397.1 - 0.054 13.7 1.6 0.075 13.3 1.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaphilin PF15290.6 ORY93397.1 - 0.27 10.8 6.0 0.039 13.6 1.2 2.0 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp OrfB_Zn_ribbon PF07282.11 ORY93397.1 - 0.4 10.6 4.5 1.1 9.3 4.5 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DDHD PF02862.17 ORY93398.1 - 3.6e-32 112.3 9.7 2.2e-28 100.0 9.7 2.7 1 1 0 1 1 1 1 DDHD domain DUF913 PF06025.12 ORY93398.1 - 0.0036 16.3 5.9 0.0076 15.3 0.3 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) DUF676 PF05057.14 ORY93398.1 - 0.069 12.6 0.0 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DLH PF01738.18 ORY93398.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family OrfB_Zn_ribbon PF07282.11 ORY93399.1 - 0.0031 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY93400.1 - 2.8e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Voldacs PF03517.13 ORY93403.1 - 1.5e-21 77.0 0.2 2.2e-21 76.5 0.2 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Glyco_transf_20 PF00982.21 ORY93404.1 - 1.9e-162 541.3 0.0 2.6e-162 540.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY93404.1 - 3.6e-73 245.5 0.0 5.8e-73 244.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Bclt PF15318.6 ORY93404.1 - 0.038 13.8 0.2 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis S6PP PF05116.13 ORY93404.1 - 0.064 12.8 0.0 0.94 8.9 0.0 2.3 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Nt_Gln_amidase PF09764.9 ORY93404.1 - 0.068 12.8 0.3 0.17 11.5 0.3 1.6 1 0 0 1 1 1 0 N-terminal glutamine amidase DUF167 PF02594.16 ORY93404.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 DUF501 PF04417.12 ORY93405.1 - 2.2 8.1 4.5 5.9 6.7 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF501) Ribosomal_L1 PF00687.21 ORY93406.1 - 2.8e-31 108.9 2.3 2.8e-31 108.9 2.3 2.3 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family CDC45 PF02724.14 ORY93406.1 - 2.4 6.4 14.0 3.6 5.8 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Mitofilin PF09731.9 ORY93406.1 - 3.4 6.4 35.1 5.7 5.7 35.1 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dicty_REP PF05086.12 ORY93406.1 - 5.9 4.7 12.9 8.6 4.2 12.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.7 ORY93406.1 - 7.9 4.5 14.7 11 4.0 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_L14 PF00238.19 ORY93407.1 - 3e-47 159.7 0.3 3.3e-47 159.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF4448 PF14610.6 ORY93408.1 - 6.5e-11 42.4 0.3 1.3e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 ORY93408.1 - 0.00059 20.5 0.8 0.00059 20.5 0.8 2.7 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Epiglycanin_C PF14654.6 ORY93408.1 - 0.0038 17.2 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region DUF4690 PF15756.5 ORY93408.1 - 0.0072 16.9 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage LapA_dom PF06305.11 ORY93408.1 - 0.079 12.8 0.3 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2062 PF09835.9 ORY93408.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Wzy_C_2 PF11846.8 ORY93408.1 - 1.8 8.4 4.7 0.89 9.4 0.2 2.3 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ApoO PF09769.9 ORY93409.1 - 2.2e-29 102.1 3.5 2e-27 95.7 0.1 2.7 2 1 1 3 3 3 2 Apolipoprotein O EF-G-binding_N PF07299.11 ORY93409.1 - 0.006 17.1 0.7 0.006 17.1 0.7 1.8 2 0 0 2 2 2 1 Elongation factor G-binding protein, N-terminal Apolipoprotein PF01442.18 ORY93409.1 - 0.006 16.5 3.0 0.62 9.9 0.2 2.3 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain DLP_helical PF18709.1 ORY93409.1 - 0.0079 15.4 2.7 0.04 13.1 0.3 2.1 1 1 1 2 2 2 1 Dynamin-like helical domain DUF842 PF05811.13 ORY93409.1 - 0.014 15.1 0.6 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) ParB PF08775.10 ORY93409.1 - 0.022 15.2 1.0 0.022 15.2 1.0 2.2 2 1 1 3 3 3 0 ParB family WXG100 PF06013.12 ORY93409.1 - 0.031 14.5 5.7 0.26 11.5 1.1 3.2 2 2 0 2 2 2 0 Proteins of 100 residues with WXG HisKA_3 PF07730.13 ORY93409.1 - 0.034 14.7 0.1 6.3 7.4 0.0 2.7 2 1 0 2 2 2 0 Histidine kinase SF-assemblin PF06705.11 ORY93409.1 - 0.036 13.4 5.2 0.72 9.2 1.0 2.1 2 0 0 2 2 2 0 SF-assemblin/beta giardin Pox_A28 PF04584.14 ORY93409.1 - 0.047 13.9 0.2 0.087 13.0 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A28 family HMMR_N PF15905.5 ORY93409.1 - 0.048 13.1 5.2 1.5 8.2 0.3 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Prominin PF05478.11 ORY93409.1 - 0.049 11.6 1.7 0.16 9.9 1.7 1.7 1 1 0 1 1 1 0 Prominin Laminin_II PF06009.12 ORY93409.1 - 0.057 13.4 3.2 0.51 10.4 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II COMPASS-Shg1 PF05205.12 ORY93409.1 - 0.063 14.0 2.8 3 8.6 0.0 2.7 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Phasin PF05597.11 ORY93409.1 - 0.082 12.9 5.6 3.7 7.6 0.2 2.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4363 PF14276.6 ORY93409.1 - 0.14 12.3 1.4 3.2 7.9 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) GAS PF13851.6 ORY93409.1 - 0.19 11.1 6.6 0.37 10.1 0.8 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF883 PF05957.13 ORY93409.1 - 0.2 12.3 9.4 14 6.4 3.4 3.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 ORY93409.1 - 0.42 11.2 8.9 3.4 8.3 1.6 3.1 2 1 0 2 2 2 0 YtxH-like protein Csm1_N PF18504.1 ORY93409.1 - 0.47 10.8 5.7 1.9 8.9 1.1 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain RNAse_A_bac PF18431.1 ORY93409.1 - 0.58 11.1 4.5 0.36 11.8 0.7 2.1 1 1 0 2 2 2 0 Bacterial CdiA-CT RNAse A domain RRF PF01765.19 ORY93409.1 - 1.1 9.2 7.0 6.5 6.7 0.8 2.3 2 0 0 2 2 2 0 Ribosome recycling factor TMPIT PF07851.13 ORY93409.1 - 1.8 7.7 5.7 4.4 6.5 1.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF1548 PF07579.11 ORY93409.1 - 1.8 8.9 4.2 63 3.9 0.1 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1548) DUF5344 PF17279.2 ORY93409.1 - 2.3 8.9 8.6 11 6.7 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5344) DDE_3 PF13358.6 ORY93410.1 - 0.00018 21.3 0.1 0.00033 20.4 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease PhetRS_B1 PF18262.1 ORY93410.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.7 1 1 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain ALS_ss_C PF10369.9 ORY93411.1 - 3.8e-16 59.0 0.0 3.9e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 ORY93411.1 - 1.9e-11 43.5 0.1 4.9e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORY93411.1 - 3.1e-08 33.3 0.1 6e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain LytR_C PF13399.6 ORY93411.1 - 0.11 13.4 0.0 0.24 12.4 0.0 1.6 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator GRDP-like PF07173.12 ORY93415.1 - 1.2e-23 84.4 3.3 3e-12 47.4 0.1 3.7 4 0 0 4 4 4 3 Glycine-rich domain-containing protein-like zinc_ribbon_10 PF10058.9 ORY93415.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Hist_deacetyl PF00850.19 ORY93416.1 - 1.7e-86 290.5 0.1 2.1e-86 290.2 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain CENP-S PF15630.6 ORY93417.1 - 7.4e-29 100.0 0.6 9e-29 99.7 0.6 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY93417.1 - 4e-09 36.6 0.2 5.1e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ORY93417.1 - 0.00034 21.0 0.2 0.00038 20.8 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY93417.1 - 0.026 14.8 0.6 0.036 14.4 0.6 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY93417.1 - 0.046 13.8 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY93417.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.16 ORY93417.1 - 0.09 12.8 0.1 0.16 12.0 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit COA2 PF17051.5 ORY93421.1 - 2.7e-07 30.5 0.5 3.9e-07 30.0 0.5 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 NDK PF00334.19 ORY93422.1 - 4.4e-34 117.4 0.0 5.7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Aldolase_II PF00596.21 ORY93423.1 - 2.2e-48 164.7 0.0 2.5e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PRA-PH PF01503.17 ORY93423.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Bromo_TP PF07524.13 ORY93424.1 - 3.8e-15 55.7 0.0 6.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 ORY93424.1 - 3.5e-11 42.8 7.2 6.4e-11 42.0 7.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY93424.1 - 3.9e-07 29.5 5.1 6.9e-07 28.7 5.1 1.3 1 0 0 1 1 1 1 PHD-finger AAA_23 PF13476.6 ORY93424.1 - 0.41 11.1 2.0 0.69 10.4 2.0 1.3 1 0 0 1 1 1 0 AAA domain Thioredoxin_7 PF13899.6 ORY93425.1 - 1.6e-18 66.6 0.0 3.6e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 ORY93425.1 - 1.2e-14 53.8 0.4 3e-14 52.5 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 ORY93425.1 - 9.3e-12 45.0 0.1 1.8e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 ORY93425.1 - 0.008 16.6 0.0 0.02 15.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain UIM PF02809.20 ORY93425.1 - 0.042 13.8 0.4 0.11 12.4 0.4 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.15 ORY93425.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Myc_N PF01056.18 ORY93425.1 - 0.51 10.2 8.4 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Zn_clus PF00172.18 ORY93427.1 - 6.7e-05 22.9 13.3 0.0001 22.3 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Astro_capsid_p PF12226.8 ORY93427.1 - 0.0024 17.1 7.9 0.0024 17.1 7.9 1.7 2 0 0 2 2 2 1 Turkey astrovirus capsid protein AT_hook PF02178.19 ORY93427.1 - 0.15 12.0 1.1 0.37 10.8 1.1 1.7 1 0 0 1 1 1 0 AT hook motif Sigma70_ner PF04546.13 ORY93427.1 - 1.8 8.4 9.3 0.18 11.7 3.4 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.12 ORY93427.1 - 7 5.9 18.6 0.52 9.6 13.1 2.0 2 0 0 2 2 2 0 NOA36 protein BAR_3 PF16746.5 ORY93428.1 - 3.8e-54 183.9 6.2 6.7e-54 183.1 6.2 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 ORY93428.1 - 2.1e-39 134.2 0.2 5.9e-39 132.8 0.2 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 ORY93428.1 - 4.4e-20 72.1 4.4 1.2e-10 41.8 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 ORY93428.1 - 1.7e-14 54.2 0.1 3.2e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 ORY93428.1 - 2.9e-14 53.2 0.9 1.5e-05 25.4 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) BAR PF03114.18 ORY93428.1 - 2.1e-13 50.5 5.5 3.4e-13 49.8 5.5 1.3 1 0 0 1 1 1 1 BAR domain Ank_5 PF13857.6 ORY93428.1 - 1.4e-10 41.2 0.7 1e-07 32.1 0.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY93428.1 - 3.4e-08 33.1 0.0 0.068 13.8 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ORY93428.1 - 5.1e-05 23.5 0.0 2.3 8.8 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 ORY93428.1 - 0.0042 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain zf-B_box PF00643.24 ORY93428.1 - 0.0044 17.1 0.2 0.0098 16.0 0.2 1.6 1 0 0 1 1 1 1 B-box zinc finger PH_13 PF16652.5 ORY93428.1 - 0.015 15.1 0.1 0.061 13.1 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Methyltransf_16 PF10294.9 ORY93431.1 - 3.3e-08 33.5 0.0 0.0048 16.6 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY93431.1 - 0.00072 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY93431.1 - 0.061 12.9 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain FAM176 PF14851.6 ORY93431.1 - 0.067 12.9 2.5 0.14 11.8 2.5 1.5 1 0 0 1 1 1 0 FAM176 family Methyltransf_31 PF13847.6 ORY93431.1 - 0.079 12.8 0.0 7.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain RXT2_N PF08595.11 ORY93431.1 - 0.085 12.9 3.0 0.22 11.5 3.0 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal TehB PF03848.14 ORY93431.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 ORY93431.1 - 0.17 12.6 0.0 5.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Cytomega_UL84 PF06284.11 ORY93431.1 - 0.31 9.4 0.9 0.44 9.0 0.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DNA_pol_phi PF04931.13 ORY93431.1 - 0.37 8.8 10.1 0.66 8.0 10.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 ORY93431.1 - 2.3 7.5 7.3 4.6 6.5 7.3 1.4 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_31 PF01055.26 ORY93432.1 - 6.2e-151 503.5 2.7 7.9e-151 503.2 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY93432.1 - 1.5e-32 112.2 0.5 5.8e-32 110.3 0.2 2.1 3 0 0 3 3 3 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORY93432.1 - 9.6e-09 35.4 0.2 2.7e-08 34.0 0.2 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Y_phosphatase2 PF03162.13 ORY93433.1 - 2.8e-58 196.1 0.1 3.6e-58 195.8 0.1 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY93433.1 - 1.2e-08 35.3 0.0 1.4e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY93433.1 - 0.00018 21.1 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY93433.1 - 0.00052 19.8 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2370 PF10176.9 ORY93434.1 - 2.1e-55 187.9 1.6 3.4e-44 151.2 0.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) ISK_Channel PF02060.15 ORY93434.1 - 0.02 14.6 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Anillin_N PF16018.5 ORY93434.1 - 0.17 12.5 4.1 0.13 12.9 0.7 2.1 1 1 1 2 2 2 0 Anillin N-terminus CENP-B_dimeris PF09026.10 ORY93434.1 - 0.5 10.8 9.9 3.8 8.0 0.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 ORY93434.1 - 0.5 10.8 7.4 0.87 10.0 2.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mrx7 PF10906.8 ORY93435.1 - 5.7e-06 26.5 0.4 7.2e-06 26.2 0.4 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 HD_3 PF13023.6 ORY93436.1 - 6.9e-47 159.4 1.0 8.4e-47 159.2 1.0 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ORY93436.1 - 1.3e-13 51.1 0.6 1.8e-13 50.6 0.6 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 ORY93436.1 - 4.6e-05 23.6 0.5 8.5e-05 22.8 0.5 1.5 1 0 0 1 1 1 1 HD domain MFS_1 PF07690.16 ORY93437.1 - 4.8e-09 35.6 21.4 2.2e-05 23.5 9.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY93437.1 - 2.1e-06 26.6 7.8 2.5e-06 26.3 5.2 1.8 1 1 0 2 2 2 1 MFS/sugar transport protein OppC_N PF12911.7 ORY93437.1 - 0.036 14.0 10.3 0.46 10.5 0.1 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF5337 PF17272.2 ORY93437.1 - 0.051 13.4 0.5 0.45 10.4 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF2512 PF10710.9 ORY93437.1 - 0.95 9.1 4.1 2.4 7.8 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Golgin_A5 PF09787.9 ORY93439.1 - 0.003 17.1 10.5 0.003 17.1 10.5 1.8 2 0 0 2 2 2 1 Golgin subfamily A member 5 OmpH PF03938.14 ORY93439.1 - 0.016 15.6 12.6 0.049 14.0 5.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) KxDL PF10241.9 ORY93439.1 - 0.031 14.5 4.0 0.039 14.2 2.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein HAUS-augmin3 PF14932.6 ORY93439.1 - 0.12 11.9 7.8 0.25 10.9 7.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 ORY93439.1 - 0.18 12.3 11.5 0.48 11.0 11.5 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 ORY93439.1 - 0.78 8.6 13.9 0.088 11.7 9.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 ORY93439.1 - 1.4 8.2 11.2 0.18 11.2 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NAM-associated PF14303.6 ORY93439.1 - 1.6 9.4 8.7 2.9 8.6 8.7 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3042 PF11240.8 ORY93439.1 - 1.9 8.6 5.8 49 4.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) DUF3811 PF11656.8 ORY93439.1 - 3.1 8.2 7.3 2.3 8.7 3.3 2.5 1 1 1 2 2 2 0 YjbD family (DUF3811) LETM1 PF07766.13 ORY93440.1 - 3.9e-108 360.8 1.6 3.9e-108 360.8 1.6 3.1 2 1 2 4 4 4 1 LETM1-like protein Exonuc_VII_L PF02601.15 ORY93440.1 - 7.1 6.1 24.5 8.6 5.8 18.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Septin PF00735.18 ORY93442.1 - 9e-114 379.5 0.4 1.1e-113 379.2 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY93442.1 - 1.5e-08 34.7 0.1 1e-07 32.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY93442.1 - 2.7e-06 27.4 0.1 6.1e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 ORY93442.1 - 2.1e-05 24.0 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 ORY93442.1 - 9.2e-05 22.9 0.2 0.0013 19.1 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 ORY93442.1 - 0.00015 21.3 0.1 0.0095 15.5 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 ORY93442.1 - 0.00034 19.9 0.2 0.00075 18.8 0.2 1.5 1 0 0 1 1 1 1 NB-ARC domain Dynamin_N PF00350.23 ORY93442.1 - 0.00034 20.7 0.8 0.88 9.6 0.3 2.5 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.27 ORY93442.1 - 0.00079 20.0 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 ORY93442.1 - 0.0014 18.1 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 ORY93442.1 - 0.0038 16.6 0.1 0.066 12.6 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 ORY93442.1 - 0.0044 17.1 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY93442.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY93442.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 ORY93442.1 - 0.027 14.1 0.0 0.12 12.0 0.0 2.0 2 1 0 2 2 2 0 Ras family AAA_7 PF12775.7 ORY93442.1 - 0.029 13.9 0.0 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 ORY93442.1 - 0.04 14.1 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 ORY93442.1 - 0.048 12.8 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 ORY93442.1 - 0.057 12.6 0.5 0.42 9.7 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit T2SSE PF00437.20 ORY93442.1 - 0.057 12.5 0.1 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 ORY93442.1 - 0.083 13.1 0.6 0.48 10.6 0.4 2.5 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ORY93442.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.13 ORY93442.1 - 0.1 11.6 0.2 0.27 10.2 0.2 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 ORY93442.1 - 0.15 11.8 0.1 0.37 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.6 ORY93444.1 - 1e-24 85.8 31.5 1e-07 32.1 1.3 5.4 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORY93444.1 - 6e-18 64.2 39.7 1.3e-05 25.4 1.7 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY93444.1 - 3.5e-10 39.8 36.0 0.0034 18.1 1.3 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY93444.1 - 8e-08 32.4 4.3 0.12 12.7 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY93444.1 - 4.3e-06 27.3 7.7 0.31 11.7 0.1 3.7 2 2 1 3 3 3 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY93444.1 - 0.00042 20.6 12.6 0.001 19.4 2.1 2.6 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 ORY93444.1 - 0.0039 17.5 10.0 1 9.8 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY93444.1 - 1.6 8.6 26.2 1.4 8.8 0.3 5.3 4 2 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORY93444.1 - 2.1 8.5 24.3 4.7 7.3 0.5 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY93444.1 - 8.7 6.5 11.6 1.2 9.3 2.1 3.2 2 2 1 3 3 3 0 Aberrant zinc-finger Ureide_permease PF07168.11 ORY93445.1 - 0.28 9.9 2.9 0.4 9.4 2.9 1.1 1 0 0 1 1 1 0 Ureide permease V_ATPase_I PF01496.19 ORY93445.1 - 3 5.7 6.5 3.4 5.5 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SPT16 PF08644.11 ORY93445.1 - 3.4 7.8 6.4 3.4 7.8 5.2 1.7 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) ApoLp-III PF07464.11 ORY93446.1 - 0.097 12.8 10.5 0.043 13.9 3.1 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF167 PF02594.16 ORY93446.1 - 0.1 12.7 0.1 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 Lipoprotein_6 PF01441.19 ORY93446.1 - 0.17 11.9 5.1 0.36 10.8 3.4 2.4 2 2 0 2 2 2 0 Lipoprotein Imm7 PF15585.6 ORY93446.1 - 0.29 11.4 5.6 3.2 8.1 0.8 2.7 2 1 0 2 2 2 0 Immunity protein 7 Baculo_PEP_C PF04513.12 ORY93446.1 - 0.35 10.9 7.5 1.2 9.2 3.2 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 ORY93446.1 - 4.8 7.7 8.8 39 4.8 0.8 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Asp PF00026.23 ORY93447.1 - 1.8e-39 136.0 0.1 2.1e-39 135.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY93447.1 - 2.7e-17 63.6 0.2 5e-09 36.6 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY93447.1 - 0.0054 17.3 0.4 0.037 14.7 0.4 2.2 1 1 0 1 1 1 1 Aspartyl protease Ribosomal_S24e PF01282.19 ORY93448.1 - 1e-37 127.9 0.0 1.9e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Semialdhyde_dhC PF02774.18 ORY93449.1 - 6.9e-40 137.1 0.0 9.6e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ORY93449.1 - 1.5e-30 106.1 0.0 2.6e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 ORY93449.1 - 0.0025 17.4 0.6 0.014 15.0 0.0 2.4 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 ORY93449.1 - 0.017 15.9 0.1 0.064 14.0 0.0 2.1 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 ORY93449.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KH_1 PF00013.29 ORY93450.1 - 0.0013 18.5 0.0 0.0034 17.2 0.0 1.6 2 0 0 2 2 2 1 KH domain RGS PF00615.19 ORY93451.1 - 2.6e-16 60.0 0.1 3.8e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain PDEase_I PF00233.19 ORY93452.1 - 9.5e-71 238.3 0.6 9.5e-71 238.3 0.6 2.0 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 ORY93452.1 - 0.017 15.4 0.2 0.041 14.1 0.2 1.7 1 0 0 1 1 1 0 HD domain TFIIA PF03153.13 ORY93452.1 - 0.056 13.4 8.3 0.096 12.7 8.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SSP160 PF06933.11 ORY93452.1 - 0.55 8.4 8.1 0.77 7.9 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Suf PF05843.14 ORY93452.1 - 2.7 7.9 8.4 0.87 9.5 4.8 2.0 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) eIF3_N PF09440.10 ORY93453.1 - 1.7e-46 158.0 8.2 1.7e-46 158.0 8.2 2.6 3 1 1 4 4 4 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 ORY93453.1 - 1.1e-15 58.0 1.1 6.7e-15 55.5 0.3 2.5 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 ORY93453.1 - 0.0057 16.6 0.7 0.024 14.6 0.2 2.3 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 ORY93453.1 - 0.0088 15.8 0.8 0.031 14.0 0.1 2.3 1 1 2 3 3 3 1 26S proteasome subunit RPN7 YabA PF06156.13 ORY93453.1 - 0.022 15.4 1.7 0.022 15.4 1.7 2.5 3 0 0 3 3 3 0 Initiation control protein YabA B3 PF02362.21 ORY93453.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 B3 DNA binding domain FlgN PF05130.12 ORY93453.1 - 2 8.9 11.2 0.082 13.4 3.9 2.3 3 0 0 3 3 3 0 FlgN protein Methyltransf_25 PF13649.6 ORY93454.1 - 2.8e-12 47.2 0.0 8e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY93454.1 - 1.2e-09 38.2 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY93454.1 - 1.5e-09 38.4 0.0 4.3e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93454.1 - 1.7e-06 28.7 0.0 2.7e-05 24.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY93454.1 - 8e-06 25.7 0.1 0.00014 21.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY93454.1 - 1.5e-05 24.5 0.0 4.2e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ORY93454.1 - 0.0024 18.0 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 ORY93454.1 - 0.009 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 ORY93454.1 - 0.01 15.3 0.7 0.056 12.9 0.1 2.6 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 ORY93454.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.6 ORY93454.1 - 0.067 14.2 0.0 0.31 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 ORY93454.1 - 0.067 12.7 0.0 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain MFS_2 PF13347.6 ORY93455.1 - 3.3e-09 35.8 17.1 3.3e-09 35.8 17.1 2.9 2 1 0 2 2 2 1 MFS/sugar transport protein TMEM100 PF16311.5 ORY93455.1 - 1.5 8.4 4.0 4.9 6.7 1.6 2.5 2 0 0 2 2 2 0 Transmembrane protein 100 DUF962 PF06127.11 ORY93455.1 - 3.6 7.7 6.4 1.6 8.9 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Mit_KHE1 PF10173.9 ORY93456.1 - 3.2e-44 151.3 2.0 5.8e-44 150.5 2.0 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pup PF05639.11 ORY93456.1 - 4.3 8.3 5.6 53 4.8 0.1 3.7 3 1 1 4 4 4 0 Pup-like protein SBDS PF01172.18 ORY93457.1 - 2e-16 59.9 0.0 2.4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein zf-C3HC4_2 PF13923.6 ORY93458.1 - 2.7e-08 33.5 7.5 2.7e-08 33.5 7.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY93458.1 - 7.9e-08 32.0 6.5 7.9e-08 32.0 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY93458.1 - 3.1e-06 27.1 9.9 4.5e-06 26.5 6.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 ORY93458.1 - 1.6e-05 24.7 3.7 3.4e-05 23.6 3.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 ORY93458.1 - 8.7e-05 22.3 10.6 0.0011 18.7 6.9 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY93458.1 - 0.0001 22.5 11.1 0.00013 22.2 7.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 ORY93458.1 - 0.0003 20.9 7.4 0.0003 20.9 7.4 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY93458.1 - 0.0004 20.2 10.5 0.00046 20.0 6.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY93458.1 - 0.00046 20.2 10.5 0.00056 19.9 7.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY93458.1 - 0.0031 17.7 5.1 0.0031 17.7 5.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 ORY93458.1 - 0.0034 17.5 5.0 0.0034 17.5 5.0 1.9 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 ORY93458.1 - 0.014 15.4 4.1 0.014 15.4 4.1 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 ORY93458.1 - 0.017 14.9 3.3 0.017 14.9 3.3 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_12 PF11331.8 ORY93458.1 - 0.02 14.7 0.3 0.48 10.3 0.0 2.7 2 0 0 2 2 2 0 Probable zinc-ribbon domain SAP PF02037.27 ORY93458.1 - 0.056 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 SAP domain zf-RING_4 PF14570.6 ORY93458.1 - 0.81 9.5 4.5 1.1 9.1 1.6 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UBZ_FAAP20 PF15750.5 ORY93458.1 - 4.5 7.3 6.3 1.4 8.9 0.5 2.8 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger DUF2415 PF10313.9 ORY93460.1 - 1.7e-09 37.4 0.0 3.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 ORY93460.1 - 5.2e-05 23.5 0.0 5.7 7.3 0.0 3.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 ORY93460.1 - 0.0024 16.6 0.2 0.028 13.1 0.0 2.5 2 1 2 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal Coatomer_WDAD PF04053.14 ORY93460.1 - 0.012 14.7 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Ge1_WD40 PF16529.5 ORY93460.1 - 0.013 14.5 0.1 7.2 5.5 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PapC_C PF13953.6 ORY93460.1 - 0.089 12.6 0.0 23 4.9 0.0 3.0 3 0 0 3 3 3 0 PapC C-terminal domain DUF1206 PF06724.11 ORY93462.1 - 1.6e-17 63.4 13.7 1.2e-07 31.7 1.3 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DUF4064 PF13273.6 ORY93462.1 - 0.00024 21.3 2.3 0.47 10.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) DUF1418 PF07214.12 ORY93462.1 - 0.059 13.2 0.0 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) DUF308 PF03729.13 ORY93462.1 - 1.5 9.2 9.2 4.4 7.7 0.7 3.0 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) TNFR_16_TM PF18422.1 ORY93462.1 - 2.3 8.2 4.5 2 8.4 0.3 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Mid1 PF12929.7 ORY93463.1 - 7.8e-87 292.2 15.6 2.1e-85 287.5 15.6 2.0 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 ORY93463.1 - 2.1e-05 25.1 12.1 0.0019 18.8 8.3 3.4 2 1 0 2 2 2 1 Fz domain Peptidase_Mx PF15887.5 ORY93463.1 - 0.19 11.1 0.5 0.3 10.4 0.5 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase EMP24_GP25L PF01105.24 ORY93464.1 - 4.8e-27 95.1 0.0 5.7e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Aminotran_5 PF00266.19 ORY93465.1 - 1.5e-19 70.2 0.0 2.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF3810 PF12725.7 ORY93465.1 - 0.0037 16.7 3.1 0.024 14.0 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3810) CDH1_2_SANT_HL1 PF18375.1 ORY93465.1 - 0.013 16.1 2.1 0.029 15.0 2.1 1.5 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 DUF1840 PF08895.11 ORY93465.1 - 0.014 15.7 0.2 0.025 14.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Cyclin_C PF02984.19 ORY93465.1 - 0.02 15.0 2.2 0.045 13.8 2.2 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain Aminotran_1_2 PF00155.21 ORY93465.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Peptidase_S49_N PF08496.10 ORY93465.1 - 0.074 13.1 1.9 0.12 12.4 1.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TPR_8 PF13181.6 ORY93465.1 - 0.51 10.7 2.1 0.66 10.3 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY93465.1 - 0.66 10.2 2.3 1.9 8.8 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 ORY93465.1 - 0.89 9.7 9.6 1.7 8.7 9.6 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Aminotran_5 PF00266.19 ORY93466.1 - 2.9e-23 82.4 0.0 5e-22 78.4 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORY93466.1 - 0.023 13.9 0.0 0.051 12.7 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II TPR_8 PF13181.6 ORY93466.1 - 0.37 11.1 3.0 0.95 9.8 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 ORY93467.1 - 9.8e-69 231.6 6.4 8.3e-68 228.6 1.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93467.1 - 5.1e-41 140.7 0.4 3.3e-39 134.8 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY93467.1 - 1.3e-07 31.2 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY93467.1 - 9.5e-06 25.7 11.2 0.0013 18.8 0.5 4.2 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY93467.1 - 1.1e-05 24.9 1.4 2.4e-05 23.8 1.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY93467.1 - 2.2e-05 24.2 1.8 4.7e-05 23.1 1.8 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY93467.1 - 0.00024 20.2 0.1 0.00024 20.2 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 ORY93467.1 - 0.0021 17.7 0.5 0.19 11.3 0.1 2.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 ORY93467.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 ORY93467.1 - 0.79 9.3 3.5 0.42 10.2 0.2 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 ORY93467.1 - 1.3 8.5 7.1 0.062 12.8 0.5 2.1 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL DUF2408 PF10303.9 ORY93469.1 - 0.095 13.3 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FidL_like PF15941.5 ORY93469.1 - 0.61 10.6 2.9 3 8.4 0.2 2.5 2 0 0 2 2 2 0 FidL-like putative membrane protein AMP-binding PF00501.28 ORY93470.1 - 4.9e-98 328.5 0.1 7.2e-98 327.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY93470.1 - 0.0026 18.7 0.0 0.0094 16.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4537 PF15057.6 ORY93470.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Methyltr_RsmB-F PF01189.17 ORY93471.1 - 2.8e-27 95.7 0.0 3.9e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 ORY93471.1 - 0.0079 16.0 0.0 0.046 13.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 ORY93471.1 - 0.037 14.1 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3228 PF11539.8 ORY93471.1 - 0.072 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) ETC_C1_NDUFA4 PF04800.12 ORY93471.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region Ferric_reduct PF01794.19 ORY93472.1 - 1.5e-20 73.6 11.3 1.5e-20 73.6 11.3 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY93472.1 - 1.5e-13 51.1 0.0 9.4e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY93472.1 - 1.2e-06 28.5 0.1 3.3e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY93472.1 - 0.019 15.6 0.2 0.092 13.4 0.0 2.2 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4165 PF13752.6 ORY93476.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) CFEM PF05730.11 ORY93477.1 - 0.12 12.5 14.6 0.41 10.8 14.3 1.9 1 1 1 2 2 2 0 CFEM domain Furin-like_2 PF15913.5 ORY93477.1 - 0.18 11.9 7.6 0.27 11.4 7.6 1.3 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich ECH_1 PF00378.20 ORY93478.1 - 2.1e-30 105.8 0.0 1.1e-28 100.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY93478.1 - 8.6e-10 38.6 0.0 5.8e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Herpes_BLLF1 PF05109.13 ORY93479.1 - 0.23 9.4 3.4 0.27 9.2 3.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PH PF00169.29 ORY93480.1 - 5.2e-09 36.6 0.2 1.2e-08 35.4 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 ORY93480.1 - 0.066 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 ORY93480.1 - 0.091 13.2 2.0 6.4 7.3 2.0 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 ORY93481.1 - 2.7e-72 243.3 0.0 3.9e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93481.1 - 4.8e-55 186.6 0.0 9.8e-55 185.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY93481.1 - 2.9e-05 23.5 0.0 0.056 12.7 0.0 2.4 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 ORY93481.1 - 0.01 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 RIO1 family C1_1 PF00130.22 ORY93481.1 - 0.022 14.6 10.1 0.052 13.4 10.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 ORY93481.1 - 0.26 11.4 4.6 0.74 10.0 4.6 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger Ras PF00071.22 ORY93482.1 - 1.5e-54 184.0 0.0 1.7e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY93482.1 - 1e-19 70.9 0.0 1.7e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY93482.1 - 2.1e-10 40.3 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY93482.1 - 4.6e-07 29.9 0.1 0.0023 17.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY93482.1 - 7.5e-06 25.6 0.0 1.5e-05 24.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain pPIWI_RE_Y PF18156.1 ORY93482.1 - 0.0071 16.8 0.1 0.025 15.0 0.1 1.9 2 0 0 2 2 2 1 pPIWI_RE three-gene island domain Y MMR_HSR1 PF01926.23 ORY93482.1 - 0.0074 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY93482.1 - 0.021 14.3 0.0 0.079 12.5 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ORY93482.1 - 0.047 13.5 0.8 0.07 12.9 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 ORY93482.1 - 0.12 11.5 0.2 0.56 9.3 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Reticulon PF02453.17 ORY93483.1 - 7.9e-25 87.7 5.9 1e-24 87.3 5.9 1.2 1 0 0 1 1 1 1 Reticulon PB1-F2 PF11986.8 ORY93483.1 - 0.024 14.8 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Influenza A Proapoptotic protein ApoO PF09769.9 ORY93483.1 - 3.8 7.5 5.6 9.2 6.2 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein O TIP49 PF06068.13 ORY93484.1 - 1.4e-171 570.4 0.2 1.8e-171 570.1 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY93484.1 - 8e-24 83.6 0.0 2e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORY93484.1 - 3.4e-10 40.5 0.8 1.1e-05 25.9 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY93484.1 - 2.9e-09 36.9 0.0 3.2e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY93484.1 - 4.9e-05 23.6 0.2 0.083 13.2 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY93484.1 - 0.0011 19.4 0.0 0.013 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY93484.1 - 0.0017 18.4 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY93484.1 - 0.0034 16.8 0.1 0.099 12.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 ORY93484.1 - 0.0057 16.7 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 ORY93484.1 - 0.0061 16.3 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 ORY93484.1 - 0.013 15.8 2.2 0.49 10.7 2.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY93484.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY93484.1 - 0.032 13.8 0.0 0.093 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY93484.1 - 0.077 13.5 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY93484.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 ORY93484.1 - 0.096 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 ORY93484.1 - 0.11 11.8 0.2 0.25 10.6 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 ORY93484.1 - 0.11 12.0 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region SGS PF05002.15 ORY93486.1 - 2.1e-34 117.4 1.1 2.1e-34 117.4 1.1 1.8 2 0 0 2 2 2 1 SGS domain CS PF04969.16 ORY93486.1 - 7.1e-16 59.0 0.7 1.5e-15 58.0 0.7 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 ORY93486.1 - 0.00041 20.3 0.0 0.0012 18.8 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY93486.1 - 0.0039 17.0 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY93486.1 - 0.04 14.1 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 ORY93487.1 - 5.9e-26 91.4 0.0 1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 ORY93487.1 - 2.2e-16 59.9 25.7 2.4e-07 31.3 0.8 7.3 7 1 1 8 8 8 4 WD domain, G-beta repeat M20_dimer PF07687.14 ORY93487.1 - 4.8e-08 32.9 0.0 1.1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 ORY93487.1 - 0.014 14.1 0.0 0.031 12.9 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY93487.1 - 0.023 15.0 0.0 4.9 7.5 0.0 3.3 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain LEA_2 PF03168.13 ORY93488.1 - 2.7e-06 27.8 0.1 4e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein SNARE PF05739.19 ORY93488.1 - 8.2 6.5 8.5 17 5.5 8.5 1.6 1 0 0 1 1 1 0 SNARE domain HLH PF00010.26 ORY93489.1 - 2.9e-13 49.5 2.1 7e-13 48.3 2.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SPX PF03105.19 ORY93489.1 - 0.029 14.3 11.1 0.035 14.0 11.1 1.1 1 0 0 1 1 1 0 SPX domain TSC22 PF01166.18 ORY93489.1 - 0.031 14.6 2.1 0.034 14.5 0.3 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3038 PF11237.8 ORY93489.1 - 0.18 11.8 2.5 0.3 11.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF2205 PF10224.9 ORY93489.1 - 2.6 8.1 6.2 2.6 8.1 2.8 2.4 1 1 1 2 2 2 0 Short coiled-coil protein F-box-like PF12937.7 ORY93490.1 - 1.1e-10 41.3 0.2 3.8e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY93490.1 - 8.1e-06 26.1 1.5 11 6.6 0.0 5.3 3 1 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY93490.1 - 1.3e-05 24.9 2.7 37 4.7 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 ORY93490.1 - 0.0001 22.0 1.4 3.1 7.6 0.0 4.9 2 2 2 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 ORY93490.1 - 0.23 12.1 5.6 1.5e+02 3.6 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat muHD PF10291.9 ORY93491.1 - 2.5e-15 56.6 0.0 4.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 ORY93491.1 - 5.9e-13 48.9 0.3 5.9e-13 48.9 0.3 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Pectate_lyase_3 PF12708.7 ORY93492.1 - 2.8e-05 24.1 8.2 0.00044 20.2 4.0 3.1 2 1 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 ORY93492.1 - 0.00047 20.1 14.3 0.19 11.6 2.3 2.8 1 1 2 3 3 3 3 Right handed beta helix region PHZA_PHZB PF03284.13 ORY93492.1 - 0.019 14.6 0.0 0.052 13.2 0.0 1.6 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B PhrC_PhrF PF11131.8 ORY93493.1 - 0.35 10.5 2.6 0.61 9.7 2.6 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling Aminotran_1_2 PF00155.21 ORY93494.1 - 1.9e-47 162.2 0.0 2.3e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY93494.1 - 0.065 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S6e PF01092.19 ORY93495.1 - 3e-58 195.2 0.1 3e-58 195.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e MitMem_reg PF13012.6 ORY93497.1 - 1.6e-39 134.8 0.9 3e-39 133.9 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY93497.1 - 3.7e-33 114.0 0.0 8.6e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ras PF00071.22 ORY93498.1 - 1.6e-48 164.4 0.1 1.9e-48 164.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY93498.1 - 1.3e-22 80.2 0.0 2.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY93498.1 - 3.3e-11 42.9 0.1 4.3e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY93498.1 - 0.0017 17.8 0.0 0.0026 17.1 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY93498.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Glyco_hydro_76 PF03663.14 ORY93498.1 - 0.038 13.5 0.0 0.044 13.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 AEP1 PF17049.5 ORY93498.1 - 0.06 12.4 0.1 0.075 12.1 0.1 1.0 1 0 0 1 1 1 0 ATPase expression protein 1 PRORP PF16953.5 ORY93498.1 - 0.072 12.6 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P Formyl_trans_N PF00551.19 ORY93498.1 - 0.16 11.7 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Formyl transferase Alpha-L-AF_C PF06964.12 ORY93499.1 - 3.6e-39 134.6 0.1 7.7e-39 133.5 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain DUF4082 PF13313.6 ORY93499.1 - 0.016 15.3 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) DUF512 PF04459.12 ORY93499.1 - 0.029 13.6 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Glyco_trans_4_4 PF13579.6 ORY93499.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Romo1 PF10247.9 ORY93500.1 - 0.02 15.3 0.4 0.031 14.7 0.4 1.2 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Tmemb_14 PF03647.13 ORY93500.1 - 0.062 14.0 0.7 0.1 13.3 0.7 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C Ribosomal_L21p PF00829.21 ORY93501.1 - 1.8e-24 85.9 4.3 2.4e-24 85.5 4.3 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein adh_short PF00106.25 ORY93502.1 - 1.3e-55 187.9 0.0 1.7e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY93502.1 - 3.2e-39 134.9 0.0 4e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY93502.1 - 1.4e-12 47.9 0.2 1.9e-12 47.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY93502.1 - 0.00061 19.3 0.3 0.0014 18.1 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pex14_N PF04695.13 ORY93503.1 - 1.1e-29 104.1 1.8 1.1e-29 104.1 1.8 3.9 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 ORY93503.1 - 0.00044 20.3 1.2 0.0013 18.7 0.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF2681 PF10883.8 ORY93503.1 - 0.047 14.1 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Tektin PF03148.14 ORY93503.1 - 0.058 12.1 4.3 0.028 13.2 1.1 1.8 1 1 1 2 2 2 0 Tektin family NPV_P10 PF05531.12 ORY93503.1 - 0.09 13.3 11.7 0.075 13.5 1.7 2.8 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein CdvA PF18822.1 ORY93503.1 - 0.11 12.3 8.8 2 8.3 8.7 2.3 1 1 0 1 1 1 0 CdvA-like coiled-coil domain Med9 PF07544.13 ORY93503.1 - 0.13 12.4 0.3 0.13 12.4 0.3 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF5320 PF17253.2 ORY93503.1 - 0.16 13.0 0.1 1.2 10.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF4235 PF14019.6 ORY93503.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) DUF4854 PF16146.5 ORY93503.1 - 0.47 10.8 7.4 2.7 8.3 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4854) DUF948 PF06103.11 ORY93503.1 - 0.56 10.5 6.4 0.21 11.8 0.7 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 ORY93503.1 - 0.58 10.0 5.6 3.3 7.5 0.3 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 XhlA PF10779.9 ORY93503.1 - 0.82 9.9 11.8 2 8.7 1.5 3.1 1 1 1 3 3 3 0 Haemolysin XhlA HAUS-augmin3 PF14932.6 ORY93503.1 - 1 8.9 7.1 1.6 8.2 7.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4200 PF13863.6 ORY93503.1 - 1 9.8 8.6 1.4 9.4 6.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 ORY93503.1 - 1.2 8.3 3.2 1.9 7.7 3.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 ORY93503.1 - 1.3 7.8 7.7 2.6 6.8 7.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Patatin PF01734.22 ORY93503.1 - 1.3 9.1 10.0 0.54 10.4 5.6 2.3 2 1 0 2 2 2 0 Patatin-like phospholipase CorA PF01544.18 ORY93503.1 - 1.5 8.0 5.6 2.2 7.5 5.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4164 PF13747.6 ORY93503.1 - 1.7 9.0 7.6 4.9 7.5 1.6 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Sas10_Utp3 PF04000.15 ORY93503.1 - 2.3 8.9 7.2 4.8 7.9 0.5 2.9 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Fib_alpha PF08702.10 ORY93503.1 - 3.2 7.9 5.4 9 6.5 5.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 ORY93503.1 - 4.8 7.7 8.5 13 6.3 2.5 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fmp27_WPPW PF10359.9 ORY93503.1 - 5.4 5.8 7.8 8.2 5.2 7.8 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SlyX PF04102.12 ORY93503.1 - 6.4 7.5 6.3 14 6.4 1.1 3.4 2 1 2 4 4 3 0 SlyX BST2 PF16716.5 ORY93503.1 - 7.9 7.1 9.5 8.9 7.0 1.6 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF16 PF01519.16 ORY93503.1 - 9.2 6.8 9.1 14 6.2 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Methyltransf_31 PF13847.6 ORY93506.1 - 1.2e-18 67.4 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY93506.1 - 9.9e-12 45.4 0.0 2.1e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY93506.1 - 8.7e-11 41.9 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93506.1 - 4.2e-09 37.0 0.0 7.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY93506.1 - 5.6e-09 36.5 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY93506.1 - 2.2e-08 33.9 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY93506.1 - 1.9e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 ORY93506.1 - 4.2e-05 23.9 0.0 7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TPMT PF05724.11 ORY93506.1 - 0.00063 19.5 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 ORY93506.1 - 0.00098 19.1 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY93506.1 - 0.021 14.3 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase EFP PF01132.20 ORY93506.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain DOT1 PF08123.13 ORY93506.1 - 0.065 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_9 PF08003.11 ORY93506.1 - 0.094 11.6 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 ORY93506.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain bZIP_1 PF00170.21 ORY93507.1 - 6.8e-10 38.9 11.8 1.8e-09 37.5 11.8 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY93507.1 - 1.6e-06 28.1 16.4 1.9e-06 27.9 14.0 2.3 1 1 1 2 2 2 1 Basic region leucine zipper WD40_alt PF14077.6 ORY93507.1 - 0.0022 17.8 0.4 0.0048 16.7 0.4 1.5 1 0 0 1 1 1 1 Alternative WD40 repeat motif bZIP_Maf PF03131.17 ORY93507.1 - 0.0027 18.2 7.5 0.0089 16.5 7.5 1.9 1 0 0 1 1 1 1 bZIP Maf transcription factor TSC22 PF01166.18 ORY93507.1 - 0.016 15.5 2.0 0.046 14.0 2.0 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 ORY93507.1 - 0.02 14.7 1.8 0.09 12.6 1.8 2.2 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 ORY93507.1 - 0.022 14.9 11.3 0.051 13.7 11.3 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 ORY93507.1 - 0.047 14.3 4.0 0.12 13.1 4.0 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Cnn_1N PF07989.11 ORY93507.1 - 0.051 13.7 3.3 0.12 12.5 3.3 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 GAS PF13851.6 ORY93507.1 - 0.06 12.7 7.6 0.1 11.9 7.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMCO5 PF14992.6 ORY93507.1 - 0.11 12.1 3.8 0.2 11.2 3.8 1.5 1 0 0 1 1 1 0 TMCO5 family CENP-F_leu_zip PF10473.9 ORY93507.1 - 0.15 12.1 8.6 0.26 11.3 8.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 ORY93507.1 - 0.19 12.3 8.4 0.47 11.0 8.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region CCDC-167 PF15188.6 ORY93507.1 - 0.22 11.9 5.7 0.64 10.4 5.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ASD2 PF08687.11 ORY93507.1 - 0.32 10.5 15.0 0.74 9.3 14.5 1.8 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 Taxilin PF09728.9 ORY93507.1 - 0.45 9.6 11.0 0.76 8.9 11.0 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein UPF0242 PF06785.11 ORY93507.1 - 0.53 10.4 6.9 1.3 9.1 6.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 ORY93507.1 - 1.3 9.2 10.9 3.5 7.8 10.9 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 ORY93507.1 - 1.7 8.5 6.8 1.7 8.4 4.3 2.4 1 1 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 ORY93507.1 - 3.4 6.1 37.2 15 4.0 34.0 2.6 2 1 0 2 2 2 0 Macoilin family Uso1_p115_C PF04871.13 ORY93507.1 - 8.3 6.8 11.7 1.8 8.9 4.5 2.8 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Thiolase_N PF00108.23 ORY93508.1 - 1.5e-78 263.7 4.0 2.1e-78 263.3 4.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY93508.1 - 4.9e-47 158.6 0.6 1.2e-46 157.3 0.6 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY93508.1 - 0.033 13.7 1.0 0.15 11.6 0.3 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Aldedh PF00171.22 ORY93509.1 - 2.6e-176 586.7 0.0 3e-176 586.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PYNP_C PF07831.13 ORY93509.1 - 0.033 13.9 0.2 0.1 12.3 0.2 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain LuxC PF05893.14 ORY93509.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ribosomal_S30 PF04758.14 ORY93510.1 - 1.4e-28 98.8 10.7 1.7e-28 98.6 10.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 LHC PF00556.20 ORY93512.1 - 0.14 12.3 0.8 0.21 11.8 0.8 1.3 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit IQ PF00612.27 ORY93513.1 - 3.2e-06 26.5 1.3 9.5e-06 25.0 1.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Lzipper-MIP1 PF14389.6 ORY93513.1 - 0.25 11.7 15.3 0.065 13.5 1.2 3.2 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 betaPIX_CC PF16523.5 ORY93513.1 - 1.6 8.6 6.7 0.33 10.8 0.9 2.4 1 1 0 2 2 2 0 betaPIX coiled coil DUF572 PF04502.13 ORY93513.1 - 5.5 6.5 21.8 9.1 5.8 20.9 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF572) UL45 PF05473.12 ORY93514.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like OapA_N PF08525.11 ORY93514.1 - 2.6 8.1 7.2 5.4 7.1 7.2 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif MFS_1 PF07690.16 ORY93515.1 - 1.6e-17 63.5 41.1 3.3e-17 62.5 40.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 ORY93516.1 - 2.9e-05 23.2 38.6 0.0031 16.5 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phos_pyr_kin PF08543.12 ORY93517.1 - 6.5e-92 307.3 3.1 6.5e-92 307.3 3.1 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 ORY93517.1 - 1.6e-48 165.3 0.4 1.6e-48 165.3 0.4 1.5 2 0 0 2 2 2 1 TENA/THI-4/PQQC family PfkB PF00294.24 ORY93517.1 - 4.4e-08 32.8 0.4 1.7e-07 30.9 0.4 1.9 2 1 0 2 2 2 1 pfkB family carbohydrate kinase EF-hand_1 PF00036.32 ORY93518.1 - 2.5e-37 123.6 12.1 5e-10 38.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY93518.1 - 9.2e-33 112.5 3.8 2.9e-18 66.1 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY93518.1 - 7.6e-29 97.9 12.1 6.5e-08 31.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORY93518.1 - 4.5e-28 94.7 10.3 1e-07 31.3 0.1 5.0 3 1 2 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 ORY93518.1 - 4.3e-27 93.7 11.9 7.3e-16 57.8 0.9 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 ORY93518.1 - 2e-11 44.1 0.1 1.8e-05 25.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY93518.1 - 2.9e-08 34.0 0.5 0.00025 21.3 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY93518.1 - 7.4e-08 32.3 3.2 0.0041 17.0 0.6 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 ORY93518.1 - 0.0016 18.4 5.5 0.02 14.9 0.5 3.0 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_14 PF17959.1 ORY93518.1 - 0.029 14.7 0.1 0.14 12.5 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain SurA_N_3 PF13624.6 ORY93518.1 - 0.099 12.4 0.8 0.55 10.0 0.3 2.1 1 1 2 3 3 3 0 SurA N-terminal domain DUF3349 PF11829.8 ORY93518.1 - 0.11 13.3 0.1 3.1 8.6 0.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) HHA PF05321.11 ORY93518.1 - 0.17 12.2 0.4 0.54 10.6 0.4 1.8 1 0 0 1 1 1 0 Haemolysin expression modulating protein Dockerin_1 PF00404.18 ORY93518.1 - 0.47 10.7 11.1 1.6 9.0 0.4 3.6 2 1 2 4 4 4 0 Dockerin type I domain DUF3455 PF11937.8 ORY93519.1 - 3.7e-09 37.2 0.1 5e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MT-A70 PF05063.14 ORY93520.1 - 2.8e-10 40.4 0.0 4.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 MT-A70 Methyltransf_21 PF05050.12 ORY93521.1 - 5.5e-07 29.8 0.0 1.6e-06 28.3 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase FkbM domain DUF2753 PF10952.8 ORY93521.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) DUF3510 PF12022.8 ORY93523.1 - 6.2e-37 126.8 0.1 6.2e-37 126.8 0.1 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3510) COG2 PF06148.11 ORY93523.1 - 3.5e-32 111.3 3.3 3.5e-32 111.3 3.3 3.3 5 0 0 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 ORY93523.1 - 0.00023 21.2 1.9 0.0015 18.5 0.0 3.3 3 0 0 3 3 3 1 Vps51/Vps67 Zw10 PF06248.13 ORY93523.1 - 0.0033 16.0 10.8 0.0045 15.6 9.2 2.0 3 0 0 3 3 3 1 Centromere/kinetochore Zw10 AbiGi PF10899.8 ORY93523.1 - 0.13 12.1 0.7 0.29 11.0 0.7 1.6 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin DUF520 PF04461.13 ORY93523.1 - 0.53 10.4 5.8 0.67 10.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF520) Cnd1 PF12717.7 ORY93523.1 - 0.86 9.6 5.4 0.26 11.3 0.3 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1664 PF07889.12 ORY93523.1 - 2.7 8.0 10.0 0.23 11.5 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 ORY93523.1 - 3.3 8.5 8.4 1.1 10.1 0.1 3.8 4 0 0 4 4 4 0 Occludin homology domain NPV_P10 PF05531.12 ORY93523.1 - 6.9 7.2 6.9 2.4 8.7 0.6 3.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein COX6C PF02937.15 ORY93524.1 - 0.044 13.9 0.0 0.046 13.9 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc FixS PF03597.15 ORY93524.1 - 0.17 11.6 0.6 0.22 11.3 0.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type tRNA-synt_2d PF01409.20 ORY93525.1 - 1.4e-50 172.1 2.6 3.6e-30 105.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 ORY93525.1 - 2.7e-23 82.2 0.1 1.8e-22 79.6 0.0 2.3 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 ORY93525.1 - 0.0016 17.6 0.1 0.26 10.3 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) DeoC PF01791.9 ORY93526.1 - 2.9e-16 59.8 1.6 3.6e-16 59.5 1.6 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase Sin3_corepress PF08295.12 ORY93526.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Sin3 family co-repressor Gtr1_RagA PF04670.12 ORY93527.1 - 1.6e-89 299.3 0.2 1.9e-89 299.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 ORY93527.1 - 5.3e-10 39.0 0.1 2.2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 ORY93527.1 - 4.2e-07 30.2 0.1 1.3e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY93527.1 - 6e-06 25.9 0.1 1.3e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Ras family FYRC PF05965.14 ORY93528.1 - 0.00014 22.0 0.0 0.0004 20.5 0.0 1.8 1 1 0 1 1 1 1 F/Y rich C-terminus SET PF00856.28 ORY93529.1 - 3.2e-20 73.2 0.0 1.6e-19 71.0 0.0 2.2 1 1 0 1 1 1 1 SET domain AWS PF17907.1 ORY93529.1 - 2.6e-13 49.7 9.2 2.6e-13 49.7 9.2 2.1 2 0 0 2 2 2 1 AWS domain WW PF00397.26 ORY93529.1 - 2.5e-08 33.9 1.8 7.3e-08 32.4 1.8 1.9 1 0 0 1 1 1 1 WW domain SRI PF08236.11 ORY93529.1 - 4.9e-08 33.0 1.8 1.3e-07 31.7 1.8 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.11 ORY93529.1 - 0.022 14.8 0.1 0.056 13.5 0.1 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Thioredoxin PF00085.20 ORY93530.1 - 2.8e-63 210.3 0.0 2.5e-32 110.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 ORY93530.1 - 1.7e-14 53.9 0.0 1.4e-06 27.9 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY93530.1 - 6.4e-12 45.9 0.0 7.1e-05 23.2 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORY93530.1 - 6.7e-07 29.4 0.0 0.032 14.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 ORY93530.1 - 1.1e-06 28.6 0.1 0.032 14.2 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 ORY93530.1 - 3.5e-06 27.2 0.0 0.038 14.3 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like TraF PF13728.6 ORY93530.1 - 7.6e-06 25.9 0.0 0.12 12.1 0.0 3.1 3 0 0 3 3 3 2 F plasmid transfer operon protein HyaE PF07449.11 ORY93530.1 - 0.00029 20.8 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 ORY93530.1 - 0.0022 17.7 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin ERp29 PF07749.12 ORY93530.1 - 0.0092 16.9 0.6 0.02 15.8 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Redoxin PF08534.10 ORY93530.1 - 0.024 14.4 0.1 5.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin NTF2 PF02136.20 ORY93531.1 - 1.8e-36 125.4 0.2 2e-36 125.2 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 ORY93531.1 - 0.023 13.9 0.2 0.15 11.2 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DUF4440 PF14534.6 ORY93531.1 - 0.074 13.5 0.0 0.091 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) cobW PF02492.19 ORY93532.1 - 5.8e-39 133.5 0.0 7.4e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORY93532.1 - 7.8e-15 54.6 0.0 1.6e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ORY93532.1 - 0.015 15.3 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 ORY93532.1 - 0.02 14.6 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY93532.1 - 0.03 14.7 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 ORY93532.1 - 0.034 14.2 0.2 0.064 13.3 0.2 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 ORY93532.1 - 0.041 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 ORY93532.1 - 0.054 13.8 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 ORY93532.1 - 0.071 12.6 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DAP3 PF10236.9 ORY93532.1 - 0.071 12.3 0.0 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.6 ORY93532.1 - 0.078 13.3 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY93532.1 - 0.079 12.7 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 ORY93532.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 ORY93532.1 - 0.12 11.3 0.0 0.36 9.7 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 ORY93532.1 - 0.15 12.6 0.8 0.25 11.8 0.7 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY93532.1 - 0.16 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 NTPase Whi5 PF08528.11 ORY93533.1 - 0.00038 20.0 0.4 0.00066 19.2 0.4 1.4 1 0 0 1 1 1 1 Whi5 like QWRF PF04484.12 ORY93533.1 - 2.3 7.9 12.8 3 7.5 12.8 1.1 1 0 0 1 1 1 0 QWRF family Tetraspanin PF00335.20 ORY93534.1 - 0.07 12.8 5.1 0.061 13.0 1.7 2.0 1 1 1 2 2 2 0 Tetraspanin family DUF1772 PF08592.11 ORY93534.1 - 0.4 11.0 8.3 0.035 14.4 1.9 2.3 1 1 3 4 4 4 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 ORY93535.1 - 1.7e-55 188.3 0.0 2.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93535.1 - 5.6e-37 127.4 0.0 7.1e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY93535.1 - 6e-06 25.4 0.1 9.5e-06 24.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY93535.1 - 3e-05 23.5 0.0 6.5e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY93535.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY93535.1 - 0.0075 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 ORY93535.1 - 0.055 12.8 0.1 0.12 11.7 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CpXC PF14353.6 ORY93535.1 - 0.059 13.4 0.6 3.8 7.6 0.1 2.3 2 0 0 2 2 2 0 CpXC protein RIO1 PF01163.22 ORY93535.1 - 0.06 12.9 0.3 0.25 10.9 0.3 1.8 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 ORY93535.1 - 0.084 11.6 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Cyclin_N PF00134.23 ORY93536.1 - 3.1e-16 59.3 0.0 3.7e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY93536.1 - 9.6e-08 32.5 0.0 1.2e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin SPX PF03105.19 ORY93537.1 - 4.2e-28 99.4 12.8 2.4e-15 57.4 4.9 3.0 1 1 1 2 2 2 2 SPX domain DUF5638 PF18688.1 ORY93537.1 - 0.11 12.8 0.1 5.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5638) EXS PF03124.14 ORY93538.1 - 1.1e-74 251.8 19.6 1.3e-74 251.5 19.6 1.0 1 0 0 1 1 1 1 EXS family Fungal_trans PF04082.18 ORY93539.1 - 6.2e-21 74.6 0.0 9.8e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PCMT PF01135.19 ORY93540.1 - 2.5e-68 230.0 0.0 2.9e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORY93540.1 - 4.4e-08 33.1 0.0 5.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY93540.1 - 2.4e-07 31.4 0.0 8e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY93540.1 - 2.4e-05 23.8 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ORY93540.1 - 0.00017 22.1 0.0 0.0003 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY93540.1 - 0.00022 21.1 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY93540.1 - 0.00037 20.1 0.0 0.00052 19.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 ORY93540.1 - 0.00068 19.7 0.0 0.00091 19.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY93540.1 - 0.0039 16.5 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ORY93540.1 - 0.0047 16.4 0.0 0.0061 16.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 ORY93540.1 - 0.016 14.3 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.17 ORY93540.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_16 PF10294.9 ORY93540.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 ORY93540.1 - 0.038 13.9 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 ORY93540.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_3 PF01596.17 ORY93540.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.6 ORY93540.1 - 0.13 13.3 0.0 0.21 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 ORY93540.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 FtsJ PF01728.19 ORY93540.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 ORY93540.1 - 0.18 11.2 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.10 ORY93540.1 - 0.22 11.2 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TPR_MLP1_2 PF07926.12 ORY93541.1 - 7e-17 61.7 55.7 4.5e-16 59.1 26.9 5.8 1 1 5 6 6 6 2 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 ORY93541.1 - 0.0046 16.8 1.3 0.0046 16.8 1.3 5.2 2 1 1 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) DUF4201 PF13870.6 ORY93541.1 - 0.0057 16.4 12.5 0.0057 16.4 12.5 5.9 3 1 2 5 5 5 2 Domain of unknown function (DUF4201) Spc7 PF08317.11 ORY93541.1 - 0.092 11.6 93.8 0.056 12.3 23.9 4.6 1 1 3 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 ORY93541.1 - 0.095 13.2 87.6 0.16 12.4 30.5 4.3 1 1 3 4 4 4 0 Fez1 ATG16 PF08614.11 ORY93541.1 - 0.17 12.1 99.3 0.35 11.1 23.7 5.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) GAS PF13851.6 ORY93541.1 - 0.21 10.9 92.4 0.024 14.0 19.6 7.3 1 1 4 7 7 7 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 ORY93541.1 - 0.25 10.9 86.5 0.12 11.9 8.4 4.4 1 1 2 3 3 3 0 Intermediate filament protein WND PF07861.11 ORY93542.1 - 0.011 15.1 1.1 0.014 14.8 1.1 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region DIL PF01843.19 ORY93543.1 - 2.5e-21 75.9 5.0 2.5e-21 75.9 5.0 2.0 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 ORY93543.1 - 6.1e-14 52.4 0.0 6.1e-13 49.2 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY93543.1 - 6.3e-12 45.4 0.3 0.00018 21.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY93543.1 - 7.1e-12 45.3 0.0 6.1e-06 26.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY93543.1 - 8.4e-11 42.2 0.1 2.6e-05 24.7 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY93543.1 - 8.2e-10 38.1 0.1 0.00026 21.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat SPX PF03105.19 ORY93543.1 - 0.67 9.8 13.5 0.51 10.2 0.0 2.2 1 1 1 2 2 2 0 SPX domain zf-HC2 PF13490.6 ORY93543.1 - 4 7.8 5.4 11 6.3 0.2 3.4 3 0 0 3 3 3 0 Putative zinc-finger Sporozoite_P67 PF05642.11 ORY93543.1 - 4.4 5.3 8.4 1.7 6.6 2.3 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SUR7 PF06687.12 ORY93544.1 - 3.1e-12 46.6 12.0 4e-12 46.2 12.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family PMP22_Claudin PF00822.20 ORY93544.1 - 0.017 15.0 4.8 0.043 13.7 4.3 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family MFS_1 PF07690.16 ORY93544.1 - 3.6 6.4 13.0 8.8 5.1 8.8 2.6 2 1 0 2 2 2 0 Major Facilitator Superfamily Diphthamide_syn PF01866.17 ORY93545.1 - 1.7e-121 405.4 0.0 2e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COX15-CtaA PF02628.15 ORY93546.1 - 1.2e-109 366.3 4.6 1.5e-109 366.0 4.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Orthoreo_P10 PF07204.11 ORY93546.1 - 0.15 12.0 1.4 0.22 11.5 0.3 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Tox-HNH-HHH PF15637.6 ORY93546.1 - 0.18 12.0 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif SSP160 PF06933.11 ORY93546.1 - 0.85 7.7 6.3 1.3 7.1 6.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3042 PF11240.8 ORY93546.1 - 2.7 8.1 4.8 8.3 6.5 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) GTP1_OBG PF01018.22 ORY93547.1 - 5.9e-46 155.9 5.2 4.1e-29 101.2 3.0 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 ORY93547.1 - 5.8e-24 84.4 0.0 1.1e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY93547.1 - 3e-12 46.3 0.0 5.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 ORY93547.1 - 4.8e-06 26.1 0.0 7.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY93547.1 - 3.2e-05 23.4 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_C PF08438.10 ORY93547.1 - 0.00024 21.6 0.1 0.00063 20.3 0.1 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal GTP_EFTU PF00009.27 ORY93547.1 - 0.0018 17.8 0.1 2.6 7.5 0.1 3.0 2 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY93547.1 - 0.0026 17.8 0.0 0.42 10.7 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 ORY93547.1 - 0.02 14.9 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 ORY93547.1 - 0.062 12.3 0.2 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 ORY93547.1 - 0.07 12.9 0.0 3.4 7.4 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 ORY93547.1 - 0.073 13.6 0.0 0.14 12.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AvrE_T3Es PF11725.8 ORY93547.1 - 0.12 9.6 0.0 0.16 9.2 0.0 1.1 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) HAUS2 PF15003.6 ORY93547.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 RsgA_GTPase PF03193.16 ORY93547.1 - 0.16 11.9 0.0 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Glyco_hydro_43 PF04616.14 ORY93548.1 - 1.3e-46 159.2 2.8 1.6e-46 158.9 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 F-box-like PF12937.7 ORY93549.1 - 4.1e-06 26.6 0.7 1.5e-05 24.8 0.7 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY93549.1 - 0.0017 18.2 0.3 0.0064 16.4 0.3 2.0 1 0 0 1 1 1 1 F-box domain LRR_2 PF07723.13 ORY93549.1 - 2.3 9.0 5.1 1.2 10.0 1.2 2.8 2 1 0 2 2 2 0 Leucine Rich Repeat Glyco_hydro_43 PF04616.14 ORY93550.1 - 2.2e-47 161.7 1.0 2.7e-47 161.5 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3739 PF12545.8 ORY93550.1 - 0.015 15.8 0.1 0.089 13.3 0.1 2.1 2 0 0 2 2 2 0 Filamentous haemagglutinin family outer membrane protein Glyco_hydro_68 PF02435.16 ORY93550.1 - 0.025 13.4 0.1 0.83 8.4 0.0 2.7 2 1 1 3 3 3 0 Levansucrase/Invertase NicO PF03824.16 ORY93551.1 - 0.00092 18.6 0.4 0.0012 18.2 0.4 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein TMEM51 PF15345.6 ORY93551.1 - 0.0023 17.8 0.0 0.0023 17.8 0.0 2.0 1 1 1 2 2 2 1 Transmembrane protein 51 Amnionless PF14828.6 ORY93551.1 - 0.01 14.7 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 1 Amnionless DUF2681 PF10883.8 ORY93551.1 - 0.014 15.8 0.1 0.019 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) OSTbeta PF15048.6 ORY93551.1 - 0.017 15.2 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein CcmD PF04995.14 ORY93551.1 - 0.019 15.0 0.8 0.039 14.0 0.8 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4834 PF16118.5 ORY93551.1 - 0.02 15.8 0.0 0.032 15.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ly49 PF08391.10 ORY93551.1 - 0.026 14.9 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Cortexin PF11057.8 ORY93551.1 - 0.03 14.2 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Cortexin of kidney Herpes_gE PF02480.16 ORY93551.1 - 0.046 12.5 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FtsL PF04999.13 ORY93551.1 - 0.068 13.2 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Cell division protein FtsL T2SSC PF11356.8 ORY93551.1 - 0.11 12.4 0.3 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system protein C HemY_N PF07219.13 ORY93551.1 - 0.11 12.7 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 HemY protein N-terminus TMEMspv1-c74-12 PF11044.8 ORY93551.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Flocculin_t3 PF13928.6 ORY93553.1 - 0.2 12.2 0.2 0.5 10.9 0.2 1.6 1 0 0 1 1 1 0 Flocculin type 3 repeat Metallophos PF00149.28 ORY93554.1 - 2.4e-19 70.6 0.3 4e-19 69.9 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 ORY93554.1 - 1.7e-15 57.4 0.8 1.7e-15 57.4 0.8 1.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 ORY93554.1 - 2.1e-10 41.3 0.3 8.2e-10 39.4 0.1 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 ORY93554.1 - 0.00091 19.5 0.0 0.0027 17.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cyclin PF08613.11 ORY93555.1 - 6.5e-13 49.4 0.0 1.5e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY93555.1 - 8.1e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain ATG16 PF08614.11 ORY93556.1 - 7.2e-06 26.4 0.2 7.2e-06 26.4 0.2 2.5 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 ORY93556.1 - 0.0012 18.4 15.6 0.041 13.4 5.7 2.3 2 0 0 2 2 2 2 Golgin subfamily A member 5 APG6_N PF17675.1 ORY93556.1 - 0.003 18.1 12.9 0.098 13.2 1.8 2.3 2 0 0 2 2 2 2 Apg6 coiled-coil region Fez1 PF06818.15 ORY93556.1 - 0.0091 16.5 12.2 0.021 15.3 2.2 2.2 2 0 0 2 2 2 1 Fez1 Cluap1 PF10234.9 ORY93556.1 - 0.014 14.8 14.0 0.26 10.6 1.4 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 FapA PF03961.13 ORY93556.1 - 0.016 13.8 9.4 0.067 11.8 3.1 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Lectin_N PF03954.14 ORY93556.1 - 0.016 14.9 3.7 0.58 9.9 0.5 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain HMMR_N PF15905.5 ORY93556.1 - 0.017 14.6 2.6 0.017 14.6 2.6 2.4 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal BRE1 PF08647.11 ORY93556.1 - 0.028 14.5 5.3 0.028 14.5 5.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FPP PF05911.11 ORY93556.1 - 0.03 12.5 16.8 0.01 14.1 4.1 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4763 PF15960.5 ORY93556.1 - 0.038 13.3 17.1 0.24 10.7 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) FKS1_dom1 PF14288.6 ORY93556.1 - 0.045 14.1 1.3 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Atg14 PF10186.9 ORY93556.1 - 0.16 11.0 11.7 1.6 7.7 0.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ORY93556.1 - 0.2 11.0 3.8 0.55 9.5 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Muted PF14942.6 ORY93556.1 - 0.22 11.8 15.9 0.059 13.7 3.8 2.4 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein GAS PF13851.6 ORY93556.1 - 0.34 10.2 21.3 0.1 11.9 3.6 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 ORY93556.1 - 0.37 10.9 17.9 2 8.5 5.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 ORY93556.1 - 0.41 10.6 26.7 2.7 8.0 10.6 2.8 2 2 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Xpo1 PF08389.12 ORY93556.1 - 0.57 10.2 4.4 1.4 8.9 3.1 2.1 1 1 1 2 2 2 0 Exportin 1-like protein Mod_r PF07200.13 ORY93556.1 - 0.63 10.1 18.8 0.51 10.4 2.0 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 ORY93556.1 - 0.65 10.1 11.3 0.33 11.0 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 ORY93556.1 - 0.78 9.8 21.2 0.31 11.1 3.9 3.9 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 ORY93556.1 - 0.94 10.1 19.7 0.14 12.7 5.1 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 ORY93556.1 - 1.1 9.3 21.5 4.4 7.4 11.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cnn_1N PF07989.11 ORY93556.1 - 1.2 9.4 26.6 0.55 10.4 6.2 2.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 ORY93556.1 - 1.5 8.9 17.7 1.4 9.0 4.1 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 ORY93556.1 - 2.3 8.7 27.9 0.18 12.3 8.0 3.4 2 1 1 3 3 3 0 Cell division protein ZapB KLRAQ PF10205.9 ORY93556.1 - 2.3 8.5 20.3 3.8 7.8 1.6 3.3 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Phage_HK97_TLTM PF06120.11 ORY93556.1 - 2.8 7.1 8.3 0.55 9.4 1.5 2.1 2 0 0 2 2 2 0 Tail length tape measure protein DUF812 PF05667.11 ORY93556.1 - 5.8 5.7 16.3 2.7 6.8 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Phage_GP20 PF06810.11 ORY93556.1 - 5.9 6.7 10.2 1.1 9.0 3.0 2.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 TMPIT PF07851.13 ORY93556.1 - 8.5 5.5 9.3 11 5.2 2.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein RhoGEF PF00621.20 ORY93557.1 - 2.5e-26 93.0 0.0 4.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 ORY93557.1 - 5.2e-21 75.5 1.2 1.2e-19 71.0 1.2 2.2 1 1 0 1 1 1 1 CNH domain PH_5 PF15405.6 ORY93557.1 - 8.3e-07 29.2 0.0 1.2e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Inhibitor_I10 PF12559.8 ORY93557.1 - 0.039 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Serine endopeptidase inhibitors FecCD PF01032.18 ORY93558.1 - 0.17 10.9 12.9 0.042 12.9 7.5 2.0 2 0 0 2 2 2 0 FecCD transport family DUF3810 PF12725.7 ORY93558.1 - 1.2 8.4 6.9 0.56 9.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Ribosomal_L7Ae PF01248.26 ORY93560.1 - 3e-26 91.0 0.0 3.8e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 ORY93560.1 - 0.00078 19.3 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 ORY93560.1 - 0.0023 18.0 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 RhoGAP PF00620.27 ORY93561.1 - 1.6e-40 138.4 0.0 2.3e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 ORY93561.1 - 0.013 14.7 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Barstar PF01337.18 ORY93561.1 - 0.078 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Barstar (barnase inhibitor) DUF4627 PF15425.6 ORY93563.1 - 0.038 13.6 0.4 0.053 13.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) DUF4625 PF15418.6 ORY93563.1 - 0.039 14.2 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Ashwin PF15323.6 ORY93563.1 - 0.15 12.0 1.2 0.22 11.5 1.2 1.2 1 0 0 1 1 1 0 Developmental protein WD40 PF00400.32 ORY93564.1 - 1.7e-12 47.6 7.2 4.9e-05 24.0 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93564.1 - 1.3e-05 25.4 0.0 0.12 12.7 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY93564.1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORY93564.1 - 0.0099 15.8 0.1 0.36 10.8 0.0 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF382 PF04037.13 ORY93565.1 - 4.6e-59 198.1 1.2 4.6e-59 198.1 1.2 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 ORY93565.1 - 1.7e-19 69.4 5.3 3.5e-19 68.4 5.3 1.6 1 0 0 1 1 1 1 PSP Terminase_4 PF05119.12 ORY93565.1 - 0.05 14.0 0.3 0.05 14.0 0.3 2.6 2 0 0 2 2 2 0 Phage terminase, small subunit zf-C2H2 PF00096.26 ORY93566.1 - 0.00012 22.3 17.9 0.1 13.1 0.3 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY93566.1 - 0.00032 21.3 17.2 0.25 12.3 0.2 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY93566.1 - 0.0031 17.7 13.6 0.2 11.8 3.9 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger CHORD PF04968.12 ORY93566.1 - 0.022 15.5 9.0 0.45 11.3 0.1 3.2 3 0 0 3 3 3 0 CHORD LAGLIDADG_3 PF14528.6 ORY93567.1 - 0.0012 19.1 0.1 1.7 9.0 0.0 3.1 3 0 0 3 3 3 2 LAGLIDADG-like domain Arrestin_N PF00339.29 ORY93568.1 - 4.1e-05 23.7 0.0 0.022 14.8 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORY93568.1 - 0.062 12.5 0.3 0.094 11.9 0.3 1.2 1 0 0 1 1 1 0 Rgp1 SNF2_N PF00176.23 ORY93569.1 - 3.2e-77 259.6 0.5 9.2e-77 258.1 0.5 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 ORY93569.1 - 4.2e-42 142.8 2.6 4.2e-42 142.8 2.6 3.0 3 1 1 4 4 4 1 SLIDE HAND PF09110.11 ORY93569.1 - 2.5e-28 99.0 7.1 2.5e-28 99.0 7.1 4.5 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 ORY93569.1 - 1.9e-19 70.0 0.0 1e-18 67.6 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY93569.1 - 1.4e-12 48.0 0.0 1.4e-12 48.0 0.0 3.6 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY93569.1 - 8.2e-06 25.7 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 ORY93569.1 - 2.9e-05 24.2 0.1 0.47 10.7 0.0 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain AAA_14 PF13173.6 ORY93569.1 - 0.013 15.5 6.0 0.067 13.2 0.1 3.1 3 0 0 3 3 3 0 AAA domain DBINO PF13892.6 ORY93569.1 - 0.034 14.5 0.1 0.034 14.5 0.1 6.2 8 1 1 9 9 9 0 DNA-binding domain AAA_22 PF13401.6 ORY93569.1 - 0.12 12.7 0.5 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Kelch_5 PF13854.6 ORY93570.1 - 1.6e-22 79.0 0.0 2e-07 30.8 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 ORY93570.1 - 9.1e-16 57.7 1.1 5.4e-11 42.5 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY93570.1 - 2.7e-15 56.0 0.9 7.1e-06 26.1 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 ORY93570.1 - 6e-13 48.1 0.0 0.0049 16.4 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 ORY93570.1 - 7.8e-13 47.9 0.3 0.014 15.3 0.0 4.5 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 ORY93570.1 - 6.4e-12 45.7 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 ORY93570.1 - 1.7e-10 40.7 0.5 7.6e-05 22.6 0.0 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain RAG2 PF03089.14 ORY93570.1 - 2.8e-05 23.3 0.1 0.00012 21.2 0.1 2.0 1 1 0 1 1 1 1 Recombination activating protein 2 MAGI_u5 PF16666.5 ORY93570.1 - 0.018 15.2 3.9 0.04 14.1 3.9 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI TFIIA PF03153.13 ORY93570.1 - 0.21 11.5 3.9 0.31 11.0 3.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rhodanese PF00581.20 ORY93571.1 - 1.2e-23 83.7 0.0 1.2e-11 45.0 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.6 ORY93571.1 - 0.12 12.2 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 ThiC-associated domain 2OG-FeII_Oxy_3 PF13640.6 ORY93574.1 - 2.8e-18 66.6 0.0 5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 ORY93574.1 - 3.2e-08 34.1 0.0 5.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CAF1A PF12253.8 ORY93574.1 - 0.14 12.4 4.4 0.29 11.3 4.4 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Arrestin_N PF00339.29 ORY93575.1 - 8.5e-08 32.4 0.0 3.7e-06 27.0 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY93575.1 - 6.4e-06 26.7 0.4 0.0046 17.4 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Meth_synt_2 PF01717.18 ORY93576.1 - 5e-153 509.1 0.0 6.1e-145 482.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY93576.1 - 1.4e-111 373.0 0.0 1.2e-104 350.2 0.1 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 ORY93576.1 - 2.1e-05 23.8 0.0 0.77 8.8 0.0 3.4 3 0 0 3 3 3 3 Uroporphyrinogen decarboxylase (URO-D) Vps39_2 PF10367.9 ORY93577.1 - 3.1e-22 79.1 0.0 6.6e-21 74.8 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 ORY93577.1 - 5.2e-11 42.7 0.0 3.2e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 ORY93577.1 - 4e-10 39.9 0.6 1.7e-08 34.7 0.1 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 ORY93577.1 - 2.5e-08 33.9 2.3 0.093 12.6 0.0 3.7 3 0 0 3 3 3 3 Region in Clathrin and VPS Ifi-6-16 PF06140.13 ORY93578.1 - 2e-08 34.0 7.2 2.5e-08 33.7 7.2 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF1515 PF07439.11 ORY93578.1 - 0.046 13.7 0.1 0.29 11.2 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) HMG_box PF00505.19 ORY93579.1 - 0.045 14.2 2.3 0.12 12.8 2.3 1.8 1 0 0 1 1 1 0 HMG (high mobility group) box Death PF00531.22 ORY93579.1 - 0.078 13.1 0.3 0.36 11.0 0.3 2.2 1 1 1 2 2 2 0 Death domain Trehalase PF01204.18 ORY93580.1 - 4.2e-127 425.1 7.8 2.4e-126 422.6 7.8 1.8 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 ORY93580.1 - 2.1e-07 30.2 3.7 8.7e-07 28.2 3.7 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase MFS_1 PF07690.16 ORY93581.1 - 1.2e-40 139.5 28.8 6.6e-40 137.1 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY93581.1 - 3.7e-07 29.8 1.9 3.7e-07 29.8 1.9 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB SPW PF03779.14 ORY93581.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.8 3 0 0 3 3 3 0 SPW repeat DUF2540 PF10802.8 ORY93581.1 - 0.54 10.4 2.5 3.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) UPF0242 PF06785.11 ORY93582.1 - 0.047 13.8 21.3 0.085 13.0 14.3 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AflR PF08493.10 ORY93582.1 - 0.063 12.7 0.1 10 5.5 0.1 2.2 2 0 0 2 2 2 0 Aflatoxin regulatory protein DUF1514 PF07438.11 ORY93582.1 - 0.19 11.6 0.9 0.88 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) V_ATPase_I PF01496.19 ORY93582.1 - 0.6 8.0 5.8 0.92 7.3 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.19 ORY93582.1 - 1.8 8.3 30.7 0.14 11.9 22.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family kleA_kleC PF17383.2 ORY93582.1 - 3.4 8.1 11.3 4.8 7.6 1.8 3.0 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Acetyltransf_11 PF13720.6 ORY93582.1 - 4.7 7.7 7.6 0.44 11.0 0.3 2.8 3 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SNARE_assoc PF09335.11 ORY93583.1 - 5.6e-08 33.3 0.1 5.6e-08 33.3 0.1 2.9 3 1 0 4 4 4 1 SNARE associated Golgi protein DUF3169 PF11368.8 ORY93583.1 - 0.0055 16.2 0.2 0.51 9.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3169) Metallophos PF00149.28 ORY93584.1 - 8.2e-16 59.1 0.2 1.7e-15 58.1 0.0 1.6 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 ORY93584.1 - 9.9e-07 29.2 0.5 2.6e-06 27.9 0.5 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 ORY93584.1 - 0.0011 19.8 1.3 0.0026 18.6 0.2 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C RabGAP-TBC PF00566.18 ORY93585.1 - 3e-42 144.7 0.2 5e-42 144.0 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 ORY93585.1 - 1.2e-24 87.1 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93585.1 - 8e-17 61.4 0.0 1.7e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 ORY93585.1 - 2.7e-08 34.3 0.0 6.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 ORY93585.1 - 0.003 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.32 ORY93586.1 - 6.5e-54 178.7 22.6 5.8e-08 33.3 0.5 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat F-box-like PF12937.7 ORY93586.1 - 2.2e-13 49.8 0.3 4.3e-13 48.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 ORY93586.1 - 4.6e-12 45.4 14.8 0.0078 14.9 0.3 6.8 3 2 3 7 7 7 6 Nucleoporin Nup120/160 F-box PF00646.33 ORY93586.1 - 2.6e-09 36.7 0.0 5.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORY93586.1 - 1e-08 35.3 2.2 0.44 10.9 0.0 5.6 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 ORY93586.1 - 0.0033 17.3 0.5 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 F-box Nucleoporin_N PF08801.11 ORY93586.1 - 0.0033 16.2 0.1 17 4.0 0.0 4.1 3 1 1 4 4 4 1 Nup133 N terminal like PALB2_WD40 PF16756.5 ORY93586.1 - 0.0096 14.9 6.0 5.7 5.8 0.4 3.9 3 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 ORY93586.1 - 0.01 15.2 0.0 2.7 7.3 0.0 2.9 2 1 0 3 3 3 0 WD40-like domain HARP PF07443.13 ORY93586.1 - 0.13 12.0 0.0 27 4.5 0.0 2.7 2 0 0 2 2 2 0 HepA-related protein (HARP) Mcp5_PH PF12814.7 ORY93587.1 - 3.1e-25 88.6 0.5 3.1e-25 88.6 0.5 1.8 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Synthase_beta PF11421.8 ORY93588.1 - 0.41 11.4 0.1 0.41 11.4 0.1 2.0 2 0 0 2 2 2 0 ATP synthase F1 beta subunit YbgS PF13985.6 ORY93589.1 - 0.087 13.1 0.0 0.087 13.1 0.0 1.6 2 0 0 2 2 2 0 YbgS-like protein Rsa3 PF14615.6 ORY93590.1 - 3.9e-16 58.3 0.1 8.2e-16 57.3 0.1 1.6 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Cwf_Cwc_15 PF04889.12 ORY93590.1 - 0.78 9.4 25.2 1 9.0 25.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 ORY93590.1 - 2.5 6.8 12.8 3.3 6.4 12.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 ORY93590.1 - 3.8 5.6 27.7 4.5 5.4 27.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 ORY93590.1 - 4.4 6.6 24.5 6.2 6.1 24.5 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_B_palm PF14792.6 ORY93592.1 - 3.3e-21 75.6 0.0 5.9e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 ORY93592.1 - 3.3e-20 71.7 0.1 7.6e-20 70.5 0.1 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 ORY93592.1 - 5.8e-20 71.2 0.0 1.7e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 ORY93592.1 - 1.7e-14 53.9 0.2 4.7e-13 49.3 0.2 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 ORY93592.1 - 0.00043 20.5 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.6 ORY93592.1 - 0.11 13.1 0.0 2.1 9.0 0.0 2.5 1 1 2 3 3 3 0 Helix-hairpin-helix domain Glyco_hydro_31 PF01055.26 ORY93593.1 - 5.8e-142 474.0 0.5 8.7e-142 473.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY93593.1 - 2e-27 95.7 0.0 4.8e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORY93593.1 - 2.9e-07 30.7 0.3 2.5e-06 27.7 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like GHL15 PF14885.6 ORY93593.1 - 0.032 14.2 0.1 0.057 13.4 0.1 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Glyco_hydro_31 PF01055.26 ORY93594.1 - 5.3e-149 497.1 2.9 6.8e-149 496.8 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY93594.1 - 9.2e-33 112.9 0.1 2.8e-32 111.3 0.1 1.8 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORY93594.1 - 1.5e-08 34.8 0.5 5.2e-08 33.1 0.2 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like GH101_N PF17995.1 ORY93594.1 - 0.056 13.1 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal SNF2_N PF00176.23 ORY93595.1 - 9.2e-55 185.8 0.0 1.4e-54 185.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 ORY93595.1 - 7.9e-18 65.3 4.4 1.8e-17 64.1 4.4 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 ORY93595.1 - 3.8e-17 62.6 0.0 7.9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY93595.1 - 1.3e-06 27.8 0.0 5.9e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORY93595.1 - 2.7e-06 27.5 0.0 6.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Melibiase PF02065.18 ORY93596.1 - 2.5e-109 365.4 0.0 3.3e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 ORY93596.1 - 8.1e-44 150.1 0.1 1.2e-43 149.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 ORY93596.1 - 8.6e-15 55.0 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 ORY93596.1 - 9.9e-07 28.1 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Melibiase_2 PF16499.5 ORY93596.1 - 0.00013 21.3 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Glyco_hydro_31 PF01055.26 ORY93596.1 - 0.00044 19.6 0.1 0.00055 19.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Acid_phosphat_B PF03767.14 ORY93596.1 - 0.18 11.4 1.1 0.6 9.6 0.2 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TPR_7 PF13176.6 ORY93597.1 - 0.016 15.2 0.1 0.045 13.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY93597.1 - 0.061 13.5 0.3 0.16 12.1 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 ORY93598.1 - 2.9e-18 65.4 41.2 1.3e-07 31.7 1.1 6.6 8 0 0 8 8 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY93598.1 - 5.9e-18 64.2 35.6 0.0004 20.7 0.2 7.7 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY93598.1 - 8.9e-11 41.7 38.4 0.0025 18.5 0.5 7.7 8 0 0 8 8 7 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORY93598.1 - 1.1e-10 42.0 23.6 0.0034 18.0 0.1 5.5 3 2 2 5 5 5 4 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORY93598.1 - 2.8e-05 24.0 16.1 0.043 13.8 0.0 5.9 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY93598.1 - 0.00014 22.1 15.8 0.57 10.5 2.3 3.7 1 1 1 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY93598.1 - 0.00018 21.7 15.9 0.11 12.7 0.5 4.1 1 1 2 4 4 4 2 Aberrant zinc-finger zf-C2H2_2 PF12756.7 ORY93598.1 - 0.004 17.5 18.2 0.017 15.5 3.7 4.0 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY93598.1 - 0.0058 16.9 13.1 0.05 13.9 0.2 4.6 5 0 0 5 5 4 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 ORY93598.1 - 0.012 15.7 0.5 0.012 15.7 0.5 6.2 5 1 1 6 6 6 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 ORY93598.1 - 0.014 15.2 7.7 0.99 9.2 0.4 3.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 ORY93598.1 - 0.089 13.2 0.6 0.089 13.2 0.6 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORY93598.1 - 0.22 11.5 6.4 34 4.5 0.2 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 ORY93598.1 - 0.28 10.8 3.8 1.4 8.6 0.2 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 ORY93598.1 - 0.66 9.7 12.5 4 7.1 0.3 4.7 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2225 PF09986.9 ORY93598.1 - 1.1 9.0 5.5 1.4 8.6 2.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 ORY93598.1 - 2.4 8.1 10.1 43 4.1 0.5 4.5 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) DUF629 PF04780.12 ORY93598.1 - 2.8 6.4 16.8 2.9 6.3 0.8 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF629) zf-H2C2_5 PF13909.6 ORY93598.1 - 4.4 7.1 19.1 0.94 9.3 0.1 5.4 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-DNA_Pol PF08996.10 ORY93598.1 - 5.1 6.8 12.9 0.36 10.5 0.5 3.1 1 1 2 4 4 4 0 DNA Polymerase alpha zinc finger SYS1 PF09801.9 ORY93599.1 - 2.4e-41 141.3 10.6 2.9e-41 141.0 10.6 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TP53IP5 PF15331.6 ORY93599.1 - 0.055 13.6 3.6 0.076 13.2 3.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Spt20 PF12090.8 ORY93599.1 - 0.2 11.3 13.0 0.27 10.8 13.0 1.3 1 0 0 1 1 1 0 Spt20 family MTABC_N PF16185.5 ORY93599.1 - 4.6 6.7 11.1 4.2e+02 0.3 11.1 2.3 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region SUIM_assoc PF16619.5 ORY93599.1 - 8.8 6.5 23.2 0.65 10.1 9.4 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SHD1 PF03983.12 ORY93600.1 - 2.1e-29 101.1 0.0 3.7e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 ORY93600.1 - 4e-15 55.4 0.1 1.6e-09 37.4 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ORY93600.1 - 4.4e-11 42.2 0.0 3.2e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 ORY93600.1 - 3.3e-08 33.1 0.0 8.7e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF1720 PF08226.11 ORY93600.1 - 0.0065 16.9 23.2 0.0065 16.9 23.2 9.3 6 2 2 8 8 8 1 Domain of unknown function (DUF1720) SH3_3 PF08239.11 ORY93600.1 - 0.0099 16.1 0.3 0.029 14.7 0.3 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SAM_4 PF18017.1 ORY93600.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_L37 PF08561.10 ORY93601.1 - 4.3e-19 69.2 17.2 5.7e-19 68.8 2.4 3.0 1 1 2 3 3 3 2 Mitochondrial ribosomal protein L37 GST_N_3 PF13417.6 ORY93602.1 - 3.2e-08 33.9 0.0 6.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY93602.1 - 1.5e-07 31.6 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY93602.1 - 3e-06 27.1 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_2 PF13410.6 ORY93602.1 - 8.1e-05 22.6 0.0 0.0003 20.8 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY93602.1 - 0.00036 20.8 0.0 0.00067 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY93602.1 - 0.00062 19.9 0.0 0.0016 18.6 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORY93602.1 - 0.015 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY93602.1 - 0.022 15.1 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORY93602.1 - 0.038 14.7 0.0 0.093 13.5 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain DUF2292 PF10055.9 ORY93602.1 - 0.077 12.7 0.9 0.25 11.0 0.9 1.9 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) F-box-like PF12937.7 ORY93603.1 - 1.1e-07 31.6 3.7 1.6e-07 31.1 2.7 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY93603.1 - 0.0026 17.6 1.1 0.0057 16.5 0.7 1.8 1 1 1 2 2 2 1 F-box domain TPR_2 PF07719.17 ORY93603.1 - 0.58 10.4 2.7 27 5.2 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M41 PF01434.18 ORY93605.1 - 1.1e-64 217.8 0.6 1.8e-64 217.1 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORY93605.1 - 7.4e-43 146.1 0.0 3.6e-42 143.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY93605.1 - 2.9e-12 46.2 0.0 7.6e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY93605.1 - 2.6e-05 24.7 2.7 0.0011 19.4 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 ORY93605.1 - 4.1e-05 23.0 0.0 7.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 ORY93605.1 - 8.7e-05 22.5 0.0 0.00025 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY93605.1 - 0.00013 22.2 0.3 0.04 14.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 ORY93605.1 - 0.00015 21.5 0.0 0.0011 18.7 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 ORY93605.1 - 0.007 16.1 0.0 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 ORY93605.1 - 0.011 16.0 0.1 0.058 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY93605.1 - 0.015 15.9 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY93605.1 - 0.017 15.3 0.0 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY93605.1 - 0.019 14.6 0.8 0.69 9.5 0.4 2.8 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 ORY93605.1 - 0.025 14.7 0.1 0.36 10.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 ORY93605.1 - 0.028 13.8 0.4 0.066 12.6 0.4 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORY93605.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 ORY93605.1 - 0.13 12.0 0.0 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 ORY93605.1 - 0.13 11.6 0.6 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 ORY93605.1 - 0.18 12.2 0.0 1.7 9.1 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 ORY93605.1 - 0.19 11.2 0.2 0.74 9.3 0.2 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region WD40 PF00400.32 ORY93606.1 - 5.4e-38 128.3 17.1 4.6e-08 33.6 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93606.1 - 0.00031 21.0 0.8 3.5 8.0 0.1 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY93606.1 - 0.029 13.0 0.9 5.4 5.5 0.3 3.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY93606.1 - 0.057 12.7 0.0 0.3 10.4 0.0 2.1 3 0 0 3 3 3 0 WD40-like domain Peptidase_M19 PF01244.21 ORY93607.1 - 6.8e-113 377.0 0.0 7.9e-113 376.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) LSM PF01423.22 ORY93608.1 - 1.5e-20 72.7 0.0 1.9e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY93608.1 - 0.0045 17.1 0.0 0.0052 16.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Zip PF02535.22 ORY93609.1 - 3.9e-59 200.5 15.3 4.7e-59 200.3 15.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Proton_antipo_N PF00662.20 ORY93609.1 - 0.076 13.1 0.8 10 6.3 0.1 3.2 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus SCA7 PF08313.12 ORY93612.1 - 2.1e-30 104.4 0.8 2.1e-30 104.4 0.8 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.11 ORY93612.1 - 7.1e-05 22.3 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) UPF0261 PF06792.11 ORY93612.1 - 0.0025 16.8 0.3 0.004 16.1 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) CENP-B_dimeris PF09026.10 ORY93612.1 - 0.056 13.8 6.1 2.5 8.6 7.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-ACC PF17848.1 ORY93612.1 - 0.16 12.0 0.4 0.29 11.3 0.4 1.4 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain CDC45 PF02724.14 ORY93612.1 - 2.5 6.3 18.1 0.052 11.9 10.0 1.9 2 0 0 2 2 2 0 CDC45-like protein GATA PF00320.27 ORY93613.1 - 5e-16 58.0 3.3 1.1e-15 57.0 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger COPIIcoated_ERV PF07970.12 ORY93614.1 - 1.2e-73 247.7 0.0 1.5e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY93614.1 - 4.3e-24 84.7 0.4 7.3e-24 83.9 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Tetraspanin PF00335.20 ORY93615.1 - 1.7e-15 57.4 7.8 2.6e-15 56.8 7.8 1.3 1 0 0 1 1 1 1 Tetraspanin family RRM_1 PF00076.22 ORY93617.1 - 1e-79 262.3 0.1 4.5e-18 64.8 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY93617.1 - 0.00023 21.1 0.0 4.7 7.3 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 ORY93617.1 - 0.00081 19.4 0.0 7 6.8 0.0 5.0 4 1 0 4 4 4 1 Limkain b1 CUT PF02376.15 ORY93617.1 - 0.0047 17.1 0.1 3.1 8.0 0.0 2.6 2 0 0 2 2 2 2 CUT domain RRM_2 PF04059.12 ORY93617.1 - 0.01 16.0 0.0 3.7 7.8 0.0 3.7 3 0 0 3 3 3 0 RNA recognition motif 2 RRM_7 PF16367.5 ORY93617.1 - 0.012 15.7 0.0 1.5 9.0 0.0 4.0 5 0 0 5 5 5 0 RNA recognition motif DUF1911 PF08929.10 ORY93617.1 - 0.027 15.3 0.5 0.094 13.5 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Sacchrp_dh_NADP PF03435.18 ORY93618.1 - 6.2e-16 58.9 0.0 8.5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 ORY93618.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family zf-CCCH PF00642.24 ORY93619.1 - 5.2e-19 67.7 16.4 1e-09 38.1 2.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) W2 PF02020.18 ORY93619.1 - 1.7e-11 44.1 3.7 2.6e-11 43.5 1.3 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon zf_CCCH_4 PF18345.1 ORY93619.1 - 3.5e-08 33.3 13.2 9.1e-05 22.4 1.1 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORY93619.1 - 1.9e-06 27.6 14.1 0.00058 19.6 2.0 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger NUDIX PF00293.28 ORY93619.1 - 2.6e-06 27.5 0.1 1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain zf-CCCH_2 PF14608.6 ORY93619.1 - 8.9e-06 26.0 12.5 0.016 15.7 1.6 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger La PF05383.17 ORY93620.1 - 1.5e-20 73.0 0.2 1.5e-20 73.0 0.2 1.9 2 0 0 2 2 2 1 La domain Sugar_tr PF00083.24 ORY93621.1 - 1.4e-122 409.8 24.2 1.6e-122 409.6 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY93621.1 - 1.2e-38 133.0 46.9 6.9e-33 114.0 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 ORY93621.1 - 0.029 14.5 1.6 0.029 14.5 1.6 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3792) Pro_dh PF01619.18 ORY93622.1 - 2.1e-74 250.7 0.5 4.7e-74 249.6 0.5 1.6 1 1 0 1 1 1 1 Proline dehydrogenase Macoilin PF09726.9 ORY93623.1 - 2 6.9 6.6 2.2 6.7 6.6 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 ORY93623.1 - 9.5 6.0 14.7 13 5.6 14.7 1.2 1 0 0 1 1 1 0 SPX domain ARF7EP_C PF14949.6 ORY93624.1 - 0.073 13.7 4.0 0.11 13.1 4.0 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Myb_DNA-bind_4 PF13837.6 ORY93626.1 - 0.0073 16.7 0.2 0.016 15.6 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain THOC2_N PF16134.5 ORY93626.1 - 0.084 11.5 0.1 0.17 10.5 0.1 1.4 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF4551 PF15087.6 ORY93626.1 - 0.16 10.8 3.5 0.21 10.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Saccharop_dh_N PF04455.12 ORY93626.1 - 0.32 11.4 1.7 32 5.0 0.0 2.9 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region Tim17 PF02466.19 ORY93627.1 - 1.3e-13 51.3 0.1 1.6e-12 47.8 0.1 2.0 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Nup188 PF10487.9 ORY93629.1 - 2.3e-78 264.1 0.0 4.6e-78 263.2 0.0 1.4 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup192 PF11894.8 ORY93629.1 - 7e-17 60.0 0.3 4.4e-08 30.8 0.1 3.3 3 0 0 3 3 3 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188_C PF18378.1 ORY93629.1 - 0.015 14.2 0.2 0.039 12.8 0.2 1.7 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain GCOM2 PF15328.6 ORY93631.1 - 4.5e-05 23.9 4.6 0.00018 22.0 3.9 2.3 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 SH3-WW_linker PF16618.5 ORY93631.1 - 0.73 10.3 14.5 0.24 11.9 11.1 1.9 1 1 1 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 PEMT PF04191.13 ORY93632.1 - 1.5e-11 44.6 1.7 1.5e-11 44.6 1.7 1.8 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 ORY93632.1 - 3.3e-09 37.1 0.1 3.3e-09 37.1 0.1 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 ORY93632.1 - 5.9e-05 22.7 0.1 5.9e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ORY93632.1 - 0.0016 18.4 3.0 0.0021 18.1 1.4 1.8 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase NnrU PF07298.11 ORY93632.1 - 0.0019 17.7 2.5 0.0022 17.5 2.5 1.1 1 0 0 1 1 1 1 NnrU protein ERG4_ERG24 PF01222.17 ORY93632.1 - 0.0034 16.2 0.4 0.0046 15.8 0.4 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Wzy_C PF04932.15 ORY93632.1 - 0.0076 15.9 7.3 0.14 11.8 0.2 2.2 1 1 1 2 2 2 2 O-Antigen ligase DUF3040 PF11239.8 ORY93632.1 - 1.3 9.3 8.2 0.43 10.9 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Lipase_GDSL_2 PF13472.6 ORY93633.1 - 3e-12 47.3 0.1 4.9e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY93633.1 - 2.4e-09 37.4 0.6 2.9e-09 37.2 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PWI PF01480.17 ORY93634.1 - 2.6e-10 40.5 0.8 8.9e-10 38.7 0.2 2.2 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 ORY93634.1 - 9.8e-09 34.9 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 ORY93635.1 - 5.9e-19 68.4 0.0 7.5e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORY93635.1 - 0.0009 18.7 0.1 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ORY93635.1 - 0.0015 18.3 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93635.1 - 0.018 15.8 0.0 0.069 13.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 ORY93635.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 ORY93635.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 ORY93635.1 - 0.15 12.7 0.0 0.33 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain SMC_N PF02463.19 ORY93638.1 - 2.8e-31 108.7 35.2 1e-30 106.9 34.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY93638.1 - 2.2e-10 41.4 20.0 2.2e-10 41.4 20.0 4.4 2 1 1 3 3 1 1 AAA domain AAA_29 PF13555.6 ORY93638.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY93638.1 - 2.7e-05 24.1 3.9 2.7e-05 24.1 3.9 2.9 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY93638.1 - 0.00011 22.0 44.8 0.0037 17.0 44.8 2.4 1 1 0 1 1 1 1 AAA ATPase domain DivIVA PF05103.13 ORY93638.1 - 0.0061 16.6 2.3 0.0061 16.6 2.3 5.1 2 1 2 5 5 4 1 DivIVA protein Filament PF00038.21 ORY93638.1 - 0.051 13.2 51.0 0.19 11.3 13.9 3.5 1 1 2 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 ORY93638.1 - 0.054 12.4 72.5 0.032 13.1 18.0 4.6 2 1 3 5 5 5 0 Spc7 kinetochore protein ABC_tran PF00005.27 ORY93638.1 - 0.12 12.8 0.0 0.12 12.8 0.0 4.1 2 1 1 3 3 2 0 ABC transporter NPV_P10 PF05531.12 ORY93638.1 - 0.46 11.0 18.8 1 9.8 0.5 5.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 ORY93638.1 - 1.7 7.2 61.0 0.074 11.7 13.9 3.8 2 1 2 4 4 4 0 AAA domain DUF3138 PF11336.8 ORY93638.1 - 6.2 5.3 6.0 0.75 8.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) SMC_N PF02463.19 ORY93639.1 - 8e-35 120.3 0.0 1.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY93639.1 - 3.4e-05 23.8 0.0 4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ORY93639.1 - 0.043 14.0 0.3 0.089 13.0 0.1 1.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rep_4 PF05797.11 ORY93639.1 - 0.069 12.3 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Herpes_IE2_3 PF03361.14 ORY93639.1 - 0.07 13.0 0.2 0.099 12.5 0.2 1.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 F-box-like PF12937.7 ORY93640.1 - 0.00014 21.6 2.0 0.00014 21.6 2.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY93640.1 - 0.1 12.5 0.5 0.3 11.0 0.5 1.8 1 1 0 1 1 1 0 F-box domain ADH_zinc_N PF00107.26 ORY93641.1 - 1.3e-20 73.7 0.1 4e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY93641.1 - 2.2e-13 50.1 0.0 4.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY93641.1 - 3.1e-06 28.3 0.0 7.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Exog_C PF18026.1 ORY93642.1 - 0.027 14.5 0.1 0.096 12.8 0.0 1.8 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain WD40 PF00400.32 ORY93643.1 - 1e-19 70.5 9.8 0.0024 18.6 0.3 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93643.1 - 6.2e-07 29.6 0.0 0.57 10.5 0.0 4.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY93643.1 - 0.00013 21.9 0.0 0.61 9.9 0.0 3.5 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY93643.1 - 0.0005 19.1 0.2 0.44 9.4 0.0 3.7 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY93643.1 - 0.0038 16.0 0.0 0.029 13.0 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40 PF00400.32 ORY93644.1 - 2.4e-13 50.3 4.0 0.02 15.8 0.0 5.7 5 1 1 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORY93644.1 - 2.3e-06 26.8 0.0 3.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 ORY93644.1 - 0.0027 18.0 0.0 2.7 8.3 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RVT PF13966.6 ORY93645.1 - 0.00086 20.0 1.2 0.00086 20.0 1.2 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Crust_neurohorm PF01147.17 ORY93715.1 - 0.035 13.9 0.2 0.076 12.9 0.2 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Plavaka PF18759.1 ORY93717.1 - 1.5e-19 70.4 0.1 1.4e-11 44.2 0.0 2.0 1 1 1 2 2 2 2 Plavaka transposase DUF1258 PF06869.12 ORY93717.1 - 0.0037 16.8 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) SET PF00856.28 ORY93720.1 - 2.9e-20 73.4 0.4 5.6e-20 72.4 0.4 1.5 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 ORY93720.1 - 4.4e-14 53.1 1.1 4.4e-14 53.1 1.1 2.4 2 1 0 2 2 2 1 Pre-SET motif HEAT PF02985.22 ORY93721.1 - 1.5e-14 52.8 0.2 0.02 15.1 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat Cnd1 PF12717.7 ORY93721.1 - 1e-08 35.4 0.2 1.5e-07 31.6 0.0 2.3 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY93721.1 - 5.8e-07 29.8 0.0 0.16 12.4 0.0 4.0 2 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 ORY93721.1 - 1.2e-05 25.7 0.1 0.034 14.7 0.1 4.5 3 1 1 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY93721.1 - 2.9e-05 24.6 0.1 0.34 11.5 0.1 3.3 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORY93721.1 - 0.00064 18.4 0.1 0.0017 17.0 0.1 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Pkinase PF00069.25 ORY93721.1 - 0.0011 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93721.1 - 0.0027 17.0 0.0 0.026 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Tti2 PF10521.9 ORY93721.1 - 0.016 14.7 0.2 1 8.8 0.0 2.9 2 1 0 3 3 3 0 Tti2 family DRIM PF07539.12 ORY93721.1 - 0.12 10.6 0.3 9.9 4.3 0.2 2.3 2 0 0 2 2 2 0 Down-regulated in metastasis IFRD PF05004.13 ORY93721.1 - 0.24 10.5 0.2 0.41 9.7 0.2 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) UBX PF00789.20 ORY93724.1 - 9.9e-17 60.9 0.0 2.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain SR-25 PF10500.9 ORY93724.1 - 0.0028 17.3 23.4 0.0028 17.3 23.4 2.2 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.8 ORY93724.1 - 0.0042 16.3 22.2 0.0068 15.6 22.2 1.3 1 0 0 1 1 1 1 SprA-related family SOBP PF15279.6 ORY93724.1 - 0.036 14.7 12.0 0.06 14.0 12.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.13 ORY93724.1 - 0.088 12.8 15.9 0.12 12.4 15.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_11 PF13086.6 ORY93724.1 - 0.19 11.4 13.8 0.35 10.6 13.8 1.4 1 0 0 1 1 1 0 AAA domain Asp-B-Hydro_N PF05279.11 ORY93724.1 - 4.8 7.2 21.8 7.4 6.6 21.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ADH_N PF08240.12 ORY93727.1 - 5.3e-23 81.0 5.8 1e-22 80.1 5.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY93727.1 - 2.4e-21 76.1 0.0 5.3e-21 75.0 0.0 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY93727.1 - 7.3e-05 22.2 0.1 0.00013 21.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ORY93727.1 - 0.00013 23.0 0.0 0.0002 22.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY93727.1 - 0.00019 20.8 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Albumin_I_a PF16720.5 ORY93727.1 - 0.0053 16.6 0.5 0.014 15.3 0.5 1.6 1 0 0 1 1 1 1 Albumin I chain a Toxin_7 PF05980.12 ORY93731.1 - 0.021 15.1 0.6 0.063 13.5 0.6 1.9 1 0 0 1 1 1 0 Toxin 7 Lectin_C PF00059.21 ORY93732.1 - 0.69 10.7 6.2 0.12 13.1 0.6 2.6 3 0 0 3 3 3 0 Lectin C-type domain RNA_pol_Rbc25 PF08292.12 ORY93733.1 - 2.3e-38 131.3 0.0 3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 ORY93733.1 - 1.3e-17 63.9 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORY93733.1 - 0.00018 21.8 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain C2 PF00168.30 ORY93734.1 - 8.3e-89 292.6 5.5 1.7e-20 73.2 0.1 6.2 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 ORY93734.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Calmodulin_bind PF07887.11 ORY93734.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Calmodulin binding protein-like Lysis_col PF02402.16 ORY93735.1 - 0.11 12.2 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Lysis protein FAA_hydrolase PF01557.18 ORY93736.1 - 2.8e-65 220.0 0.0 4.1e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Exo_endo_phos PF03372.23 ORY93737.1 - 5e-09 36.0 0.2 8.3e-09 35.3 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MEDS PF14417.6 ORY93738.1 - 0.022 14.6 1.3 0.07 13.0 1.3 1.9 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Opiods_neuropep PF01160.18 ORY93738.1 - 0.14 12.2 0.4 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide BT1 PF03092.16 ORY93738.1 - 0.2 9.8 0.6 0.25 9.5 0.6 1.2 1 0 0 1 1 1 0 BT1 family ATG16 PF08614.11 ORY93738.1 - 0.26 11.5 27.3 2.9 8.1 15.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4279 PF14106.6 ORY93738.1 - 0.44 10.8 2.8 1.3 9.2 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) ALMT PF11744.8 ORY93738.1 - 4.4 6.0 8.0 5.7 5.7 8.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.25 ORY93739.1 - 2.3e-15 56.7 0.0 4.2e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 ORY93739.1 - 0.00017 20.5 0.0 0.00017 20.5 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase Acyl-CoA_dh_1 PF00441.24 ORY93740.1 - 7.6e-29 100.9 1.3 1.2e-28 100.2 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY93740.1 - 3.3e-28 98.6 0.1 6.4e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY93740.1 - 1.3e-21 76.6 0.0 2.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY93740.1 - 2.5e-09 37.5 2.1 5.7e-09 36.4 2.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY93740.1 - 0.19 11.4 0.0 0.58 9.8 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MFS_1 PF07690.16 ORY93741.1 - 2e-40 138.8 19.8 3.2e-40 138.1 19.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SUR7 PF06687.12 ORY93741.1 - 0.13 11.9 2.9 0.17 11.5 0.4 2.4 2 0 0 2 2 2 0 SUR7/PalI family MARVEL PF01284.23 ORY93741.1 - 0.25 11.3 7.4 1.8 8.6 0.2 3.4 3 1 0 3 3 3 0 Membrane-associating domain DUF3658 PF12395.8 ORY93743.1 - 0.0031 17.4 0.2 0.0076 16.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function Tropomyosin_1 PF12718.7 ORY93743.1 - 0.0043 17.2 2.0 0.0069 16.5 2.0 1.3 1 0 0 1 1 1 1 Tropomyosin like FlxA PF14282.6 ORY93743.1 - 0.074 13.0 3.0 0.14 12.1 3.0 1.4 1 0 0 1 1 1 0 FlxA-like protein OmpH PF03938.14 ORY93743.1 - 0.11 12.8 4.1 0.051 13.9 1.7 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.8 ORY93743.1 - 0.14 12.2 3.5 0.74 9.9 1.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding LRS4 PF10422.9 ORY93743.1 - 0.15 11.6 2.4 0.29 10.7 2.4 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF948 PF06103.11 ORY93743.1 - 0.2 11.9 1.4 1.1 9.6 1.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Remorin_C PF03763.13 ORY93743.1 - 0.75 9.7 3.5 0.32 10.9 0.2 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region Prefoldin_2 PF01920.20 ORY93743.1 - 0.8 9.7 5.3 22 5.0 0.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit DHR10 PF18595.1 ORY93743.1 - 7.5 6.6 10.9 0.21 11.6 3.2 2.2 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain SPA PF08616.10 ORY93744.1 - 4.6e-12 45.9 0.0 8.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 ORY93744.1 - 0.00027 21.0 0.1 0.0023 17.9 0.1 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain Avl9 PF09794.9 ORY93744.1 - 0.0003 19.6 0.0 0.00055 18.7 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 Soyouz_module PF14313.6 ORY93745.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Mito_fiss_reg PF05308.11 ORY93745.1 - 0.2 11.7 6.4 0.32 11.0 6.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 ORY93745.1 - 1.3 8.4 8.0 2.3 7.6 8.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CIAPIN1 PF05093.13 ORY93746.1 - 9.8e-30 103.0 2.9 9.8e-30 103.0 2.9 2.1 2 1 1 3 3 3 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Rgp1 PF08737.10 ORY93746.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Rgp1 ALAD PF00490.21 ORY93747.1 - 1.6e-124 415.2 0.0 1.9e-124 415.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Cut8 PF08559.10 ORY93748.1 - 1.2e-10 41.4 0.1 1.7e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein BSP_II PF05432.11 ORY93748.1 - 0.012 15.4 0.5 0.015 15.1 0.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DpnII PF04556.12 ORY93748.1 - 0.037 13.3 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 DpnII restriction endonuclease DUF4805 PF16063.5 ORY93748.1 - 0.076 12.3 1.8 0.091 12.1 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Kelch_5 PF13854.6 ORY93749.1 - 2.6e-11 43.2 7.2 0.0016 18.4 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 ORY93749.1 - 4.8e-10 39.5 22.4 8.1e-06 26.0 0.2 6.7 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY93749.1 - 1.2e-09 38.1 11.8 0.06 13.7 0.0 6.6 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 ORY93749.1 - 1.8e-09 37.5 17.6 0.28 11.2 0.1 7.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY93749.1 - 2.9e-09 36.5 6.4 0.07 13.1 0.4 5.6 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 ORY93749.1 - 3.9e-08 32.8 7.2 0.0013 18.3 0.0 6.1 6 0 0 6 6 6 1 Kelch motif CYYR1 PF10873.8 ORY93749.1 - 0.0015 19.0 0.0 0.006 17.0 0.0 1.8 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 VSP PF03302.13 ORY93749.1 - 0.01 14.7 1.4 0.01 14.7 1.4 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein TMEM51 PF15345.6 ORY93749.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 PTP_tm PF18861.1 ORY93749.1 - 0.064 13.2 0.6 0.12 12.4 0.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 ORY93749.1 - 0.17 12.8 0.0 0.36 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 ORY93749.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Gram_pos_anchor PF00746.21 ORY93749.1 - 1.5 8.8 3.3 0.54 10.2 0.2 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Nop PF01798.18 ORY93750.1 - 1.9e-71 240.2 0.0 2.7e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 ORY93750.1 - 1.5e-39 135.7 3.1 1.5e-39 135.7 3.1 2.2 2 0 0 2 2 2 1 Prp31 C terminal domain Sld5 PF05916.11 ORY93750.1 - 0.1 13.1 0.1 0.29 11.6 0.1 1.9 1 1 0 1 1 1 0 GINS complex protein UvsY PF11056.8 ORY93750.1 - 0.15 12.4 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY RRN3 PF05327.11 ORY93750.1 - 3.6 6.0 5.7 1.1e+02 1.1 7.7 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 BCDHK_Adom3 PF10436.9 ORY93751.1 - 1.3e-45 155.2 0.0 1.7e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY93751.1 - 4e-11 43.4 0.0 3.1e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY93751.1 - 3.2e-05 23.8 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FCH PF00611.23 ORY93751.1 - 0.098 13.0 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain MARVEL PF01284.23 ORY93752.1 - 1.8e-09 37.7 7.4 2.5e-09 37.3 7.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain COX7a PF02238.15 ORY93752.1 - 0.056 13.8 1.6 6.4 7.3 0.1 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII GRP PF07172.11 ORY93752.1 - 0.096 13.4 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family AA_permease_2 PF13520.6 ORY93752.1 - 4 6.2 10.2 2.1 7.1 2.7 2.2 1 1 0 2 2 2 0 Amino acid permease EMP70 PF02990.16 ORY93753.1 - 8.7e-150 499.8 13.4 1.1e-149 499.5 13.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Phage_holin_2_1 PF04971.12 ORY93753.1 - 1.7 8.7 7.2 0.21 11.6 1.0 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S F-box PF00646.33 ORY93754.1 - 2e-05 24.3 0.2 4.3e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY93754.1 - 0.00013 21.7 0.7 0.00023 21.0 0.7 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY93754.1 - 0.13 12.2 0.4 0.3 11.0 0.3 1.8 1 1 0 1 1 1 0 F-box TMEM135_C_rich PF15982.5 ORY93755.1 - 3e-09 37.6 5.0 9.3e-09 36.0 0.6 2.4 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 ORY93755.1 - 8.8e-09 35.7 1.1 3.9e-08 33.7 0.3 2.1 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5058 PF16481.5 ORY93755.1 - 0.063 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) DUF5333 PF17267.2 ORY93756.1 - 0.012 15.8 0.5 0.021 15.0 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5333) AT_hook PF02178.19 ORY93756.1 - 0.012 15.3 3.3 0.012 15.3 3.3 13.1 12 1 1 13 13 13 0 AT hook motif Amastin PF07344.11 ORY93757.1 - 0.61 9.9 11.1 0.065 13.1 1.8 2.7 2 1 1 3 3 3 0 Amastin surface glycoprotein Orai-1 PF07856.12 ORY93757.1 - 3.2 7.4 7.3 0.13 12.0 0.7 1.9 2 0 0 2 2 2 0 Mediator of CRAC channel activity cNMP_binding PF00027.29 ORY93759.1 - 3.9e-43 145.4 0.2 2e-21 75.9 0.1 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 ORY93759.1 - 6.8e-07 28.8 0.6 1.4e-06 27.9 0.6 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SUIM_assoc PF16619.5 ORY93760.1 - 1.5e-07 31.3 0.2 0.47 10.6 4.0 5.2 4 2 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 FYVE PF01363.21 ORY93760.1 - 0.0014 18.7 2.1 0.0014 18.7 2.1 3.1 3 1 0 3 3 3 1 FYVE zinc finger ATP_bind_1 PF03029.17 ORY93761.1 - 3.2e-88 295.6 0.0 3.7e-85 285.5 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ORY93761.1 - 0.00019 21.3 0.0 0.00086 19.2 0.0 2.1 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 ORY93761.1 - 0.00019 21.7 0.1 0.048 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY93761.1 - 0.00051 19.8 0.1 0.01 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 ORY93761.1 - 0.00066 19.3 0.4 0.0084 15.7 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.23 ORY93761.1 - 0.0008 19.5 0.0 0.00099 19.2 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SPT6_acidic PF14632.6 ORY93761.1 - 0.00099 19.6 5.8 0.0019 18.7 5.8 1.4 1 0 0 1 1 1 1 Acidic N-terminal SPT6 AAA_24 PF13479.6 ORY93761.1 - 0.0017 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY93761.1 - 0.0027 18.1 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain eIF3_subunit PF08597.10 ORY93761.1 - 0.0057 16.6 0.9 0.01 15.8 0.9 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF87 PF01935.17 ORY93761.1 - 0.0064 16.6 0.1 0.027 14.6 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 ORY93761.1 - 0.0096 15.0 0.0 0.024 13.7 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY93761.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 ORY93761.1 - 0.01 16.4 0.0 0.031 14.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 ORY93761.1 - 0.013 15.4 0.0 5.3 6.9 0.0 2.8 3 0 0 3 3 3 0 NTPase SRP54 PF00448.22 ORY93761.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 ORY93761.1 - 0.028 14.4 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 ORY93761.1 - 0.029 14.3 0.1 9.3 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY93761.1 - 0.041 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 ORY93761.1 - 0.051 12.5 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.6 ORY93761.1 - 0.054 13.8 0.4 0.52 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY93761.1 - 0.066 13.6 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 ORY93761.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 ORY93761.1 - 0.096 12.0 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 ORY93761.1 - 0.097 12.8 2.5 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY93761.1 - 0.1 11.6 0.6 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 ORY93761.1 - 0.12 11.8 0.1 0.83 9.0 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 ORY93761.1 - 0.18 11.7 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 ORY93761.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.6 2 2 0 2 2 1 0 AAA domain PDZ_5 PF17817.1 ORY93762.1 - 0.068 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 PDZ domain RAWUL PF16207.5 ORY93762.1 - 0.11 13.2 0.3 12 6.7 0.1 2.5 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like WD40 PF00400.32 ORY93763.1 - 1.6e-10 41.4 11.2 1.5e-05 25.6 0.3 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat UCR_14kD PF02271.16 ORY93764.1 - 9e-38 128.3 2.3 1e-37 128.1 2.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit VapB_antitoxin PF09957.9 ORY93764.1 - 0.054 13.4 0.1 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB PAS_12 PF18095.1 ORY93764.1 - 0.061 13.0 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain F-box-like PF12937.7 ORY93765.1 - 5.5e-06 26.2 1.2 5.5e-06 26.2 1.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY93765.1 - 2.3e-05 24.2 1.4 3.5e-05 23.6 0.1 2.1 3 0 0 3 3 3 1 F-box domain TFIIA PF03153.13 ORY93766.1 - 0.0014 18.7 14.5 0.0015 18.6 14.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 ORY93766.1 - 0.0098 15.7 1.5 0.014 15.1 1.5 1.2 1 0 0 1 1 1 1 Connexin TERB2 PF15101.6 ORY93766.1 - 0.016 15.3 5.3 0.019 15.0 5.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EPL1 PF10513.9 ORY93766.1 - 0.076 13.4 5.2 0.092 13.1 5.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like SprA-related PF12118.8 ORY93766.1 - 0.15 11.2 17.3 0.2 10.8 17.3 1.1 1 0 0 1 1 1 0 SprA-related family Spt20 PF12090.8 ORY93766.1 - 0.17 11.5 20.2 0.23 11.0 20.2 1.3 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 ORY93766.1 - 0.18 10.5 6.6 0.19 10.5 6.6 1.1 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 ORY93766.1 - 0.34 11.2 7.3 0.48 10.7 7.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Folate_carrier PF01770.18 ORY93766.1 - 0.55 8.9 2.4 0.7 8.6 2.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Androgen_recep PF02166.16 ORY93766.1 - 1.3 7.8 19.3 1.6 7.5 19.3 1.2 1 0 0 1 1 1 0 Androgen receptor Suf PF05843.14 ORY93766.1 - 1.6 8.7 13.7 2 8.3 13.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CLN3 PF02487.17 ORY93766.1 - 1.6 7.7 2.9 2 7.4 2.9 1.1 1 0 0 1 1 1 0 CLN3 protein RasGEF PF00617.19 ORY93767.1 - 5.1e-30 105.0 0.0 9.9e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Ras PF00071.22 ORY93767.1 - 4.3e-10 39.4 0.0 1.9e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Ras family RasGEF_N PF00618.20 ORY93767.1 - 4.4e-05 23.7 0.1 0.00013 22.1 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA_22 PF13401.6 ORY93767.1 - 0.00012 22.4 0.0 0.0058 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ORY93767.1 - 0.054 13.7 0.0 0.43 10.8 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 ORY93767.1 - 0.084 12.8 1.5 14 5.6 0.0 3.1 3 0 0 3 3 3 0 NACHT domain UCH PF00443.29 ORY93769.1 - 1e-36 126.8 0.0 1.3e-35 123.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EcoEI_R_C PF08463.10 ORY93769.1 - 0.19 11.8 1.2 2.8 8.0 0.3 2.3 2 0 0 2 2 2 0 EcoEI R protein C-terminal Proteasome PF00227.26 ORY93770.1 - 2.1e-62 210.0 0.1 3e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY93770.1 - 3.8e-11 42.4 0.7 8.7e-11 41.3 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature BAP PF06639.11 ORY93771.1 - 0.089 13.1 0.3 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) HA2 PF04408.23 ORY93773.1 - 2e-24 85.9 0.1 5e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY93773.1 - 8.2e-22 77.4 0.0 3.1e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY93773.1 - 1.6e-11 44.5 0.0 3.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY93773.1 - 4.8e-09 36.2 0.0 9.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY93773.1 - 1e-06 29.0 0.0 3.1e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY93773.1 - 4.7e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ORY93773.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 ORY93773.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY93773.1 - 0.017 14.7 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 ORY93773.1 - 0.034 14.1 0.0 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 ORY93773.1 - 0.037 14.5 0.0 0.086 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY93773.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 ORY93773.1 - 0.054 13.2 0.0 9.5 5.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 ORY93773.1 - 0.067 13.7 0.1 0.42 11.1 0.0 2.1 1 1 1 2 2 2 0 ABC transporter Flavi_DEAD PF07652.14 ORY93773.1 - 0.072 13.1 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain HABP4_PAI-RBP1 PF04774.15 ORY93774.1 - 4.6e-05 24.2 0.5 4.6e-05 24.2 0.5 3.4 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Pkinase PF00069.25 ORY93775.1 - 9.8e-70 234.9 0.0 1.2e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93775.1 - 4.2e-36 124.6 0.0 6e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY93775.1 - 1e-09 38.1 0.2 3e-09 36.6 0.2 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_C PF00433.24 ORY93775.1 - 9e-06 26.3 3.1 2.2e-05 25.1 3.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 ORY93775.1 - 7.9e-05 22.4 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY93775.1 - 0.003 16.6 0.1 0.0065 15.4 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY93775.1 - 0.015 14.1 0.1 0.046 12.5 0.1 1.7 1 1 0 1 1 1 0 Fungal protein kinase NotI PF12183.8 ORY93775.1 - 0.067 12.5 0.2 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease NotI APH PF01636.23 ORY93775.1 - 0.15 11.9 0.1 0.48 10.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FSA_C PF10479.9 ORY93775.1 - 4.1 5.4 7.2 6 4.9 7.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 ORY93775.1 - 6.9 4.5 5.8 10 4.0 5.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SHR3_chaperone PF08229.11 ORY93776.1 - 3.9e-40 136.8 1.9 4.3e-40 136.7 1.9 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5480 PF17576.2 ORY93776.1 - 0.094 12.7 0.7 1.9 8.5 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5480) Abhydrolase_2 PF02230.16 ORY93777.1 - 4.4e-62 209.7 0.0 5.2e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY93777.1 - 4.9e-11 42.3 0.0 0.00022 20.6 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY93777.1 - 1.5e-08 34.4 0.1 6.5e-05 22.5 0.0 2.4 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 ORY93777.1 - 1.3e-07 31.4 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 ORY93777.1 - 1.7e-07 31.1 0.0 3.7e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORY93777.1 - 6.3e-06 27.0 0.0 1e-05 26.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY93777.1 - 8e-06 25.7 0.2 0.0015 18.3 0.0 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ORY93777.1 - 0.00011 22.2 0.0 0.006 16.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY93777.1 - 0.0016 18.5 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 ORY93777.1 - 0.0018 18.0 0.1 0.0024 17.5 0.1 1.5 1 1 0 1 1 1 1 Putative esterase Cutinase PF01083.22 ORY93777.1 - 0.0028 17.6 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Cutinase Esterase_phd PF10503.9 ORY93777.1 - 0.023 14.2 0.0 0.32 10.5 0.0 2.1 1 1 1 2 2 2 0 Esterase PHB depolymerase Lipase_3 PF01764.25 ORY93777.1 - 0.027 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 ORY93777.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ric8 PF10165.9 ORY93778.1 - 1.4e-103 347.5 0.0 1.8e-103 347.1 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF5584 PF17822.1 ORY93778.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5584) Cyclin PF08613.11 ORY93779.1 - 3.1e-40 138.2 0.4 3.1e-40 138.2 0.4 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY93779.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Malic_M PF03949.15 ORY93780.1 - 1.9e-94 315.7 0.0 2.5e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORY93780.1 - 2.5e-61 206.6 0.0 4e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DNA_pol_A_exo1 PF01612.20 ORY93780.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease CUE PF02845.16 ORY93781.1 - 3.8e-12 45.6 0.1 5.5e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 ORY93781.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 DMRTA motif zf-C2H2 PF00096.26 ORY93783.1 - 2.3e-16 59.3 46.0 8.6e-06 25.9 0.7 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY93783.1 - 1.1e-10 41.4 46.3 0.002 18.8 1.0 6.0 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY93783.1 - 5.2e-09 36.2 23.4 0.008 16.4 0.1 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY93783.1 - 1.5e-06 28.4 19.3 0.034 14.5 0.0 5.6 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY93783.1 - 2.4e-05 24.6 51.4 0.0028 18.0 1.8 6.9 7 1 0 7 7 6 3 Zinc-finger double domain zf-Di19 PF05605.12 ORY93783.1 - 0.00023 21.4 3.4 0.00023 21.4 3.4 4.8 3 3 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORY93783.1 - 0.00088 19.2 31.6 0.22 11.6 2.6 5.4 5 1 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY93783.1 - 0.001 19.8 5.7 0.001 19.8 5.7 3.2 1 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 ORY93783.1 - 0.0018 18.3 35.4 0.025 14.6 3.2 5.4 2 2 2 4 4 4 2 BED zinc finger zf-C2HC_2 PF13913.6 ORY93783.1 - 0.0027 17.6 27.1 0.13 12.2 2.6 5.2 5 1 0 5 5 5 3 zinc-finger of a C2HC-type Mut7-C PF01927.16 ORY93783.1 - 0.0039 17.3 0.8 0.0039 17.3 0.8 3.4 2 2 2 4 4 4 1 Mut7-C RNAse domain PHM7_cyt PF14703.6 ORY93783.1 - 0.012 15.8 2.0 0.012 15.8 2.0 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zinc_ribbon_9 PF14369.6 ORY93783.1 - 0.017 15.4 11.3 25 5.3 0.0 5.0 5 0 0 5 5 5 0 zinc-ribbon HNH_5 PF14279.6 ORY93783.1 - 0.029 14.2 12.9 0.97 9.3 0.3 4.6 5 0 0 5 5 5 0 HNH endonuclease Vps39_2 PF10367.9 ORY93783.1 - 0.034 14.6 20.6 0.25 11.8 0.2 4.4 2 2 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf_ZIC PF18366.1 ORY93783.1 - 0.096 12.8 0.1 0.096 12.8 0.1 4.1 3 1 1 4 4 4 0 Zic proteins zinc finger domain Baculo_RING PF05883.11 ORY93783.1 - 0.13 12.3 1.9 14 5.7 0.7 2.6 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF678 PF05077.12 ORY93783.1 - 0.18 11.9 4.3 0.8 9.9 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF678) Zn-ribbon_8 PF09723.10 ORY93783.1 - 0.21 11.7 18.9 15 5.8 0.4 5.0 4 1 0 4 4 4 0 Zinc ribbon domain Rep_fac-A_C PF08646.10 ORY93783.1 - 0.28 10.9 5.1 3 7.6 0.7 3.3 2 1 1 3 3 3 0 Replication factor-A C terminal domain FYVE PF01363.21 ORY93783.1 - 0.3 11.3 27.8 0.49 10.6 1.8 4.1 3 2 0 3 3 3 0 FYVE zinc finger zf-C2H2_12 PF18658.1 ORY93783.1 - 0.47 10.1 0.1 0.47 10.1 0.1 4.5 2 2 2 4 4 4 0 Zinc-finger C2H2-type zinc-ribbons_6 PF07191.12 ORY93783.1 - 0.49 10.4 16.1 0.6 10.1 0.9 4.0 3 1 0 3 3 3 0 zinc-ribbons zf-LYAR PF08790.11 ORY93783.1 - 0.52 10.3 19.8 1.3 9.0 0.7 4.9 6 0 0 6 6 4 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 ORY93783.1 - 1.5 8.7 25.7 2.7 8.0 7.3 5.0 4 1 1 5 5 5 0 SprT-like zinc ribbon domain zf-CHCC PF10276.9 ORY93783.1 - 2.4 8.3 10.6 11 6.1 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger domain zf-MYST PF17772.1 ORY93783.1 - 5.4 6.7 10.4 3.5 7.3 0.0 3.6 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 ORY93783.1 - 8.4 6.8 31.9 2.1 8.7 6.0 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Inhibitor_I78 PF11720.8 ORY93784.1 - 0.026 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORY93784.1 - 0.073 13.8 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Potato inhibitor I family KDZ PF18758.1 ORY93787.1 - 3.4e-57 193.6 0.1 9e-57 192.2 0.1 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 ORY93787.1 - 1.9e-10 40.8 0.2 3.9e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 ORY93787.1 - 4.2e-07 30.1 1.1 7.3e-07 29.3 0.3 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases DUF559 PF04480.12 ORY93787.1 - 0.31 10.9 1.8 9.3 6.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF559) Inhibitor_I78 PF11720.8 ORY93788.1 - 4.1e-05 23.5 0.1 7.1e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORY93788.1 - 0.029 15.0 0.2 0.064 13.9 0.2 1.6 1 1 0 1 1 1 0 Potato inhibitor I family Sec1 PF00995.23 ORY93789.1 - 1.8e-130 436.9 0.1 2.1e-130 436.7 0.1 1.0 1 0 0 1 1 1 1 Sec1 family IFT20 PF14931.6 ORY93789.1 - 0.0025 18.0 0.5 0.0058 16.8 0.5 1.6 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 AXE1 PF05448.12 ORY93789.1 - 0.037 12.7 0.0 0.096 11.3 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) B12-binding PF02310.19 ORY93789.1 - 0.053 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain MAP65_ASE1 PF03999.12 ORY93790.1 - 4.6e-36 124.7 4.0 1.4e-33 116.6 4.0 3.1 1 1 1 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) Muted PF14942.6 ORY93790.1 - 0.056 13.8 4.0 0.091 13.1 2.8 2.1 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein ING PF12998.7 ORY93790.1 - 0.34 11.5 4.5 21 5.8 0.4 3.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Spectrin PF00435.21 ORY93790.1 - 2.4 8.7 6.3 2.6 8.6 0.3 3.5 3 1 1 4 4 4 0 Spectrin repeat RFX_DNA_binding PF02257.15 ORY93791.1 - 3.1e-31 107.8 0.9 3.1e-31 107.8 0.9 2.0 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.16 ORY93791.1 - 8.9e-06 26.1 0.0 2.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Poxvirus D5 protein-like Fringe PF02434.16 ORY93791.1 - 0.019 14.4 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 Fringe-like Cdc6_C PF09079.11 ORY93791.1 - 0.056 13.4 0.3 0.83 9.7 0.0 2.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Glyco_tranf_2_3 PF13641.6 ORY93792.1 - 1.3e-22 80.8 0.0 1.6e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY93792.1 - 1.9e-07 31.1 0.0 3.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY93792.1 - 3.7e-06 26.5 0.7 7.8e-05 22.2 0.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 SLIDE PF09111.10 ORY93792.1 - 0.019 15.0 0.1 0.042 13.9 0.1 1.5 1 0 0 1 1 1 0 SLIDE Chitin_synth_2 PF03142.15 ORY93792.1 - 0.021 13.4 2.5 0.41 9.2 2.5 2.5 1 1 0 1 1 1 0 Chitin synthase Rax2 PF12768.7 ORY93793.1 - 2.1e-32 112.3 8.8 2.9e-28 98.8 0.0 5.8 5 3 2 7 7 7 2 Cortical protein marker for cell polarity SH3_9 PF14604.6 ORY93793.1 - 7e-10 38.6 1.4 1.1e-09 38.0 0.3 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 ORY93793.1 - 1.8e-07 30.7 0.2 3.3e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 SH3 domain DUF5122 PF17164.4 ORY93793.1 - 5.3e-05 23.4 11.4 0.35 11.2 0.3 6.4 5 0 0 5 5 5 2 Domain of unknown function (DUF5122) beta-propeller SH3_2 PF07653.17 ORY93793.1 - 5.3e-05 22.8 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 ORY93793.1 - 0.00088 19.5 4.4 0.18 12.2 0.0 5.6 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 ORY93793.1 - 0.017 15.1 0.1 0.017 15.1 0.1 5.8 6 1 0 6 6 6 0 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY93793.1 - 0.16 12.3 6.4 0.44 10.9 0.3 4.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY93793.1 - 0.23 11.0 0.0 0.23 11.0 0.0 4.5 5 0 0 5 5 5 0 Kelch motif RhoGAP PF00620.27 ORY93794.1 - 8.5e-45 152.3 0.0 1.4e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY93794.1 - 1.9e-14 54.0 0.1 5e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 ORY93794.1 - 2.9e-14 52.4 1.1 5.9e-14 51.4 1.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY93794.1 - 1.6e-11 43.9 0.1 3e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 ORY93794.1 - 3.2e-10 39.9 1.3 7e-10 38.8 1.3 1.6 1 0 0 1 1 1 1 WW domain PH_9 PF15410.6 ORY93794.1 - 2e-09 37.8 0.1 4e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 ORY93794.1 - 3.2e-08 33.1 0.1 7.4e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 ORY93794.1 - 0.0068 16.8 0.1 0.021 15.2 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF655 PF04919.12 ORY93794.1 - 0.039 13.9 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF655) DUF4859 PF16151.5 ORY93794.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) PAP_assoc PF03828.19 ORY93795.1 - 2.8e-18 65.9 0.0 1e-17 64.1 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY93795.1 - 2.1e-07 31.1 0.0 4.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIA PF03153.13 ORY93795.1 - 0.00051 20.2 31.0 0.00073 19.6 31.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Polbeta PF18765.1 ORY93795.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Macoilin PF09726.9 ORY93795.1 - 0.69 8.4 33.6 0.92 8.0 33.6 1.1 1 0 0 1 1 1 0 Macoilin family BolA PF01722.18 ORY93796.1 - 4.8e-14 52.4 0.0 1.5e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein IF4E PF01652.18 ORY93797.1 - 4.7e-40 137.0 0.2 7.3e-40 136.4 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ku PF02735.16 ORY93797.1 - 0.032 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain DAHP_snth_FXD PF18152.1 ORY93797.1 - 0.13 12.1 0.5 0.41 10.5 0.5 1.8 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain FSA_C PF10479.9 ORY93797.1 - 1.6 6.7 10.8 0.67 8.0 8.4 1.5 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus SUIM_assoc PF16619.5 ORY93797.1 - 7 6.8 32.1 0.099 12.7 12.9 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 MRP-S34 PF16053.5 ORY93798.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 Oxysterol_BP PF01237.18 ORY93799.1 - 1.7e-90 303.6 2.4 1.9e-88 296.8 2.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF5462 PF17547.2 ORY93799.1 - 0.14 11.5 0.1 0.33 10.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5462) HORMA PF02301.18 ORY93801.1 - 2.6e-06 27.2 0.0 7.2e-06 25.7 0.0 1.6 1 1 1 2 2 2 1 HORMA domain MDM31_MDM32 PF08118.11 ORY93802.1 - 1.1e-162 542.5 0.0 3e-162 541.0 0.0 1.6 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins AA_permease_2 PF13520.6 ORY93803.1 - 1.1e-56 192.4 49.9 1.4e-56 192.2 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease FAM178 PF14816.6 ORY93804.1 - 1 8.3 4.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function, FAM178 PMT PF02366.18 ORY93805.1 - 1.2e-75 254.3 14.2 1.2e-75 254.3 14.2 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY93805.1 - 5.4e-65 218.7 6.6 5.4e-65 218.7 6.6 2.5 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY93805.1 - 4.8e-40 137.4 0.5 8.6e-40 136.6 0.5 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 ORY93805.1 - 0.00034 20.9 5.3 0.00034 20.9 5.3 3.7 3 1 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Mucin_bdg PF03272.13 ORY93805.1 - 0.088 12.8 0.3 8.1 6.5 0.1 2.4 1 1 1 2 2 2 0 Putative mucin or carbohydrate-binding module Fz PF01392.22 ORY93806.1 - 3.5e-07 30.8 4.8 8e-07 29.7 4.8 1.6 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.24 ORY93806.1 - 4.1e-06 26.3 18.0 8.4e-06 25.3 18.0 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 ORY93806.1 - 1.9e-05 23.9 11.3 3.6e-05 23.1 11.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor MARVEL PF01284.23 ORY93806.1 - 0.00018 21.5 6.2 0.00018 21.5 6.2 4.1 4 1 1 5 5 5 1 Membrane-associating domain DUF4234 PF14018.6 ORY93807.1 - 0.17 12.0 2.6 0.3 11.3 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) S4 PF01479.25 ORY93808.1 - 1.3e-12 47.2 1.0 1.3e-12 47.2 1.0 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY93808.1 - 1.7e-06 28.8 0.4 2.4e-06 28.4 0.4 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 ORY93809.1 - 1.5e-47 159.6 4.2 1.5e-47 159.6 4.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 ORY93809.1 - 0.0018 17.9 0.1 0.0022 17.6 0.1 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Ribo_biogen_C PF04034.13 ORY93810.1 - 4.9e-52 175.0 0.0 6.9e-52 174.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 ORY93810.1 - 6.1e-11 42.0 0.4 1.1e-10 41.1 0.4 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 ORY93810.1 - 5.5 6.2 15.9 7.8 5.7 15.9 1.1 1 0 0 1 1 1 0 BUD22 SH3_1 PF00018.28 ORY93811.1 - 1.3e-07 31.2 0.0 3.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain RA PF00788.23 ORY93811.1 - 1.1e-06 29.1 0.1 0.0092 16.6 0.0 3.4 2 1 1 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.6 ORY93811.1 - 6.9e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 ORY93811.1 - 0.016 15.5 0.2 0.036 14.4 0.2 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF3361 PF11841.8 ORY93812.1 - 2.9e-32 111.7 0.1 6.9e-32 110.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 ORY93812.1 - 5.9e-32 111.2 0.2 1.2e-31 110.2 0.1 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 ORY93812.1 - 1.4e-22 80.6 0.0 5.9e-22 78.6 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Npa1 PF11707.8 ORY93812.1 - 0.057 12.8 0.4 0.094 12.1 0.4 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DnaJ PF00226.31 ORY93814.1 - 2.4e-17 62.8 0.1 3.9e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Adeno_E3_CR2 PF02439.15 ORY93816.1 - 0.024 14.4 0.7 0.04 13.7 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 ORY93816.1 - 5.1 7.2 20.1 0.098 12.8 5.2 3.1 2 1 1 3 3 3 0 Podoplanin THUMP PF02926.17 ORY93817.1 - 4.2e-12 46.4 0.0 7.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Sporozoite_P67 PF05642.11 ORY93817.1 - 0.0021 16.3 0.3 0.0021 16.3 0.3 1.4 2 0 0 2 2 2 1 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 ORY93817.1 - 0.014 15.1 3.3 0.014 15.1 3.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 ORY93817.1 - 0.55 9.9 5.3 0.52 10.0 1.4 2.2 2 0 0 2 2 2 0 FAM176 family Mito_carr PF00153.27 ORY93818.1 - 2.6e-67 222.8 2.7 1.5e-23 82.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PC-Esterase PF13839.6 ORY93820.1 - 1.8e-30 106.7 0.0 3.6e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DNA_pol_viral_N PF00242.17 ORY93820.1 - 0.11 11.9 0.2 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Cofilin_ADF PF00241.20 ORY93821.1 - 8.6e-27 93.3 0.2 9.7e-27 93.2 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Sel1 PF08238.12 ORY93822.1 - 7.8e-31 105.8 11.6 2.1e-06 28.2 0.0 7.4 7 0 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.6 ORY93822.1 - 0.012 16.2 5.0 1.9 9.3 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF962 PF06127.11 ORY93823.1 - 8.3e-16 57.9 0.2 9.8e-16 57.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) WHIM1 PF15612.6 ORY93824.1 - 0.046 13.3 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Rib_recp_KP_reg PF05104.12 ORY93824.1 - 8.4 7.4 8.3 27 5.8 8.3 1.8 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region zf-Mss51 PF13824.6 ORY93825.1 - 8.6e-18 64.2 12.9 1.7e-17 63.3 12.9 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 OrfB_Zn_ribbon PF07282.11 ORY93825.1 - 0.48 10.4 2.5 0.93 9.5 2.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-MYND PF01753.18 ORY93825.1 - 8.6 6.5 8.4 16 5.7 8.4 1.5 1 0 0 1 1 1 0 MYND finger eIF-6 PF01912.18 ORY93826.1 - 5.6e-84 280.4 0.4 5.6e-84 280.4 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family RasGEF PF00617.19 ORY93827.1 - 6.9e-59 199.0 0.1 1.5e-58 197.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY93827.1 - 1.6e-27 95.7 0.7 7.2e-27 93.7 0.7 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 ORY93827.1 - 4.7e-14 51.7 0.1 8.7e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY93827.1 - 2.4e-11 43.3 0.2 5.6e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 ORY93827.1 - 6.5e-10 38.9 1.4 0.00012 22.0 0.0 2.8 2 0 0 2 2 2 2 WW domain SH3_2 PF07653.17 ORY93827.1 - 4.2e-08 32.8 0.0 9.8e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PI_PP_I PF18363.1 ORY93827.1 - 0.036 14.2 0.3 69 3.7 0.0 3.9 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain NDK PF00334.19 ORY93827.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Nucleoside diphosphate kinase CTP_transf_1 PF01148.20 ORY93828.1 - 3.3e-80 269.7 23.4 4.3e-80 269.3 23.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family OSCP PF00213.18 ORY93829.1 - 2.2e-42 145.1 6.5 2.6e-42 144.9 6.5 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit polyprenyl_synt PF00348.17 ORY93830.1 - 1.4e-85 286.4 0.4 2.3e-83 279.2 0.4 2.2 1 1 0 1 1 1 1 Polyprenyl synthetase DUF4457 PF14652.6 ORY93830.1 - 0.028 13.7 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) CLP_protease PF00574.23 ORY93830.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Clp protease Apo-CIII PF05778.12 ORY93830.1 - 0.087 12.5 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Exo84_C PF16528.5 ORY93831.1 - 4.7e-52 176.8 6.9 4.7e-52 176.8 5.6 1.7 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 ORY93831.1 - 2.6e-12 46.6 0.0 6.4e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 SgrR_N PF12793.7 ORY93831.1 - 0.011 16.0 1.7 0.061 13.5 0.4 2.7 2 1 1 3 3 3 0 Sugar transport-related sRNA regulator N-term Sec5 PF15469.6 ORY93831.1 - 0.033 14.0 0.3 0.033 14.0 0.3 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 Abhydrolase_6 PF12697.7 ORY93832.1 - 2.2e-09 38.2 4.7 3.7e-09 37.5 4.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY93832.1 - 2.5e-09 37.2 0.3 5.3e-09 36.1 0.2 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY93832.1 - 7e-09 35.3 1.5 1.9e-06 27.3 0.1 2.8 2 1 0 3 3 3 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ORY93832.1 - 7.7e-05 22.6 0.9 0.00017 21.5 0.9 1.5 1 0 0 1 1 1 1 Serine hydrolase UPF0227 PF05728.12 ORY93832.1 - 0.0033 17.4 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ndr PF03096.14 ORY93832.1 - 0.0049 15.6 0.1 0.017 13.9 0.1 1.8 1 1 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 ORY93832.1 - 0.0062 15.5 0.9 0.024 13.5 0.9 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 ORY93832.1 - 0.026 14.3 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Sugar_tr PF00083.24 ORY93833.1 - 3.1e-113 379.0 19.9 3.6e-113 378.8 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY93833.1 - 9.9e-21 74.0 38.1 3.6e-15 55.7 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY93833.1 - 0.032 12.6 6.4 0.013 13.9 0.7 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pex14_N PF04695.13 ORY93833.1 - 0.19 12.4 0.1 0.41 11.3 0.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2415 PF10313.9 ORY93834.1 - 3.6e-14 52.4 2.6 1.1e-12 47.6 0.4 2.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 ORY93834.1 - 1.3e-08 35.3 11.4 0.011 16.6 2.8 5.1 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93834.1 - 6.2e-07 29.6 0.0 0.33 11.3 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 ORY93834.1 - 0.019 14.7 1.2 0.032 14.0 0.5 1.5 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Frtz PF11768.8 ORY93834.1 - 0.021 13.2 0.1 0.043 12.1 0.1 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 ORY93834.1 - 0.033 13.5 0.7 0.12 11.7 0.1 2.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 ORY93834.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Lgl_C PF08596.10 ORY93834.1 - 0.19 10.4 0.1 1.2 7.7 0.0 2.1 1 1 1 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal FGGY_C PF02782.16 ORY93835.1 - 8.7e-73 244.3 1.1 1.5e-72 243.5 1.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY93835.1 - 1.6e-71 240.7 0.0 2.3e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 ORY93835.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Cation_efflux PF01545.21 ORY93836.1 - 2.8e-51 174.1 6.6 3.4e-51 173.8 6.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 ORY93836.1 - 0.0027 17.6 0.1 0.083 12.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5134) Ribosomal_L34 PF00468.17 ORY93837.1 - 1.1e-18 66.9 6.4 1.4e-18 66.6 6.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 Dus PF01207.17 ORY93838.1 - 1.3e-54 185.4 0.0 1.7e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ORY93838.1 - 0.077 12.4 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein zf-Nse PF11789.8 ORY93839.1 - 2.2e-16 59.4 0.2 4.1e-16 58.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Fe_dep_repr_C PF02742.15 ORY93839.1 - 0.0028 17.7 0.8 0.056 13.5 0.1 2.8 3 0 0 3 3 3 1 Iron dependent repressor, metal binding and dimerisation domain zf-RING_UBOX PF13445.6 ORY93839.1 - 0.015 15.3 0.3 0.028 14.5 0.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY93839.1 - 0.067 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 ORY93839.1 - 0.13 12.0 0.9 0.33 10.7 0.9 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 ORY93839.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger AA_permease_2 PF13520.6 ORY93840.1 - 3.9e-56 190.7 27.6 4.8e-56 190.4 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease PalH PF08733.10 ORY93840.1 - 0.036 13.1 0.7 0.074 12.0 0.0 1.9 2 1 0 2 2 2 0 PalH/RIM21 Peptidase_C78 PF07910.13 ORY93841.1 - 1.7e-47 161.7 0.0 1.4e-46 158.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase family C78 UBZ_FAAP20 PF15750.5 ORY93841.1 - 0.013 15.5 0.2 0.029 14.3 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger UBA2_C PF16195.5 ORY93841.1 - 0.12 13.0 0.1 0.27 11.9 0.1 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus FGGY_N PF00370.21 ORY93842.1 - 4e-72 242.7 0.0 5.5e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ORY93842.1 - 4.9e-68 228.8 0.2 8.7e-68 228.0 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Cyclase PF04199.13 ORY93843.1 - 6.2e-15 55.6 0.0 8.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 ORY93844.1 - 1.4e-14 54.4 0.0 1.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_9 PF00759.19 ORY93845.1 - 7e-56 190.4 14.7 8.2e-56 190.2 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Adeno_E3_CR2 PF02439.15 ORY93845.1 - 0.0045 16.7 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF3094 PF11293.8 ORY93845.1 - 0.0082 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3094) TMEMspv1-c74-12 PF11044.8 ORY93845.1 - 0.035 14.1 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Zn_clus PF00172.18 ORY93846.1 - 2.3e-05 24.4 15.8 4.4e-05 23.5 15.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHD5 PF04420.14 ORY93846.1 - 0.25 11.2 1.4 0.5 10.2 1.4 1.5 1 0 0 1 1 1 0 CHD5-like protein Presenilin PF01080.17 ORY93846.1 - 0.52 9.0 3.6 0.76 8.5 3.6 1.3 1 0 0 1 1 1 0 Presenilin POPLD PF08170.12 ORY93846.1 - 2.1 8.7 6.1 0.12 12.8 0.7 1.6 2 0 0 2 2 2 0 POPLD (NUC188) domain DUF4407 PF14362.6 ORY93846.1 - 5.2 6.3 6.5 8.1 5.7 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIF PF01187.18 ORY93847.1 - 4.5e-18 65.6 0.0 5.1e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 ORY93847.1 - 0.0052 16.7 0.0 2.8 7.9 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme RINGv PF12906.7 ORY93848.1 - 5.1e-13 48.9 5.6 9.9e-13 48.0 5.6 1.5 1 0 0 1 1 1 1 RING-variant domain PBP1_TM PF14812.6 ORY93848.1 - 1.1 9.7 11.0 3.5 8.1 11.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vfa1 PF08432.10 ORY93848.1 - 1.2 9.4 3.6 2.2 8.6 3.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-RING_2 PF13639.6 ORY93848.1 - 1.4 9.4 7.7 2.8 8.4 7.7 1.5 1 0 0 1 1 1 0 Ring finger domain Nop14 PF04147.12 ORY93848.1 - 9.4 4.3 21.5 13 3.8 21.5 1.1 1 0 0 1 1 1 0 Nop14-like family RhoGEF PF00621.20 ORY93849.1 - 1.2e-31 110.4 0.1 2.9e-31 109.1 0.1 1.6 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 ORY93849.1 - 2.8e-05 24.6 0.0 5.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 ORY93849.1 - 0.0098 15.9 0.1 0.026 14.5 0.0 1.7 2 0 0 2 2 2 1 PH domain PH_5 PF15405.6 ORY93849.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain EPL1 PF10513.9 ORY93851.1 - 3.1e-23 82.9 0.1 3.1e-23 82.9 0.1 3.1 3 0 0 3 3 3 2 Enhancer of polycomb-like DUF3395 PF11875.8 ORY93851.1 - 0.12 12.2 3.4 0.28 11.0 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) MSA-2c PF12238.8 ORY93851.1 - 10 6.1 9.0 5.7 6.9 6.1 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c Glyco_hydro_18 PF00704.28 ORY93852.1 - 8e-29 101.3 0.8 2.6e-28 99.7 0.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GCP_N_terminal PF17681.1 ORY93853.1 - 1.5e-74 251.4 1.1 2.6e-74 250.6 0.1 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY93853.1 - 6.9e-63 213.0 7.4 6.9e-63 213.0 7.4 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal RabGAP-TBC PF00566.18 ORY93855.1 - 5.3e-31 108.0 0.9 2.3e-26 92.8 0.0 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain MFS_1 PF07690.16 ORY93856.1 - 1.6e-30 106.3 34.2 2.5e-16 59.6 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY93856.1 - 0.0044 15.6 30.2 0.14 10.7 2.9 3.9 2 1 2 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 ORY93856.1 - 0.32 9.8 14.8 1.3 7.8 1.9 3.2 2 2 1 3 3 3 0 MFS_1 like family Na_H_Exchanger PF00999.21 ORY93857.1 - 1e-67 228.6 32.0 1.2e-67 228.4 32.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HAMP PF00672.25 ORY93858.1 - 1.2e-62 208.1 33.7 7.2e-08 32.7 0.2 13.1 15 0 0 15 15 13 10 HAMP domain HATPase_c PF02518.26 ORY93858.1 - 1e-30 106.5 0.0 3.2e-30 104.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY93858.1 - 1.7e-26 92.6 6.6 1.1e-24 86.8 0.4 3.9 4 0 0 4 4 4 2 Response regulator receiver domain HisKA PF00512.25 ORY93858.1 - 1.2e-15 57.2 4.0 3.1e-15 56.0 0.5 3.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF1843 PF08898.10 ORY93858.1 - 0.00092 19.7 5.3 11 6.6 0.0 7.2 8 0 0 8 8 8 1 Domain of unknown function (DUF1843) HATPase_c_3 PF13589.6 ORY93858.1 - 0.00097 19.0 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1759 PF03564.15 ORY93858.1 - 0.0012 18.8 4.0 20 5.1 0.0 6.0 6 0 0 6 6 6 0 Protein of unknown function (DUF1759) SpoIIID PF12116.8 ORY93858.1 - 0.0081 16.2 16.0 35 4.6 0.1 8.6 9 0 0 9 9 9 0 Stage III sporulation protein D GatB_Yqey PF02637.18 ORY93858.1 - 0.035 14.0 25.5 3.5 7.5 0.3 8.8 9 1 0 10 10 10 0 GatB domain DUF4279 PF14106.6 ORY93858.1 - 0.14 12.4 0.0 38 4.5 0.0 4.3 5 0 0 5 5 4 0 Domain of unknown function (DUF4279) HflK_N PF12221.8 ORY93858.1 - 0.21 11.6 0.0 0.86 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Abhydrolase_8 PF06259.12 ORY93858.1 - 0.45 10.1 38.6 0.94 9.1 0.8 7.7 6 2 1 7 7 7 0 Alpha/beta hydrolase zf-C2H2 PF00096.26 ORY93859.1 - 7.9e-08 32.3 6.8 3.6e-05 24.0 0.4 3.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY93859.1 - 2.4e-07 30.9 9.7 0.00038 20.7 0.3 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY93859.1 - 0.00026 21.5 6.7 0.0094 16.7 1.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORY93859.1 - 0.0024 18.2 2.0 0.035 14.5 0.1 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY93859.1 - 0.0071 16.3 3.7 0.88 9.6 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 ORY93859.1 - 0.13 12.1 4.1 0.39 10.7 0.3 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Lin-8 PF03353.15 ORY93859.1 - 5.3 6.5 9.0 10 5.6 9.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mucin PF01456.17 ORY93859.1 - 7.1 6.6 23.3 2.2 8.3 16.9 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Sua5_yciO_yrdC PF01300.18 ORY93860.1 - 1.8e-55 187.2 0.0 2.5e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ORY93860.1 - 5.2e-31 108.0 0.0 9.9e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding ADH_zinc_N PF00107.26 ORY93861.1 - 6.1e-20 71.5 0.5 8.6e-20 71.0 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY93861.1 - 9.1e-08 33.2 0.0 1.5e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY93861.1 - 1.9e-05 24.5 0.1 6.2e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SDA1 PF05285.12 ORY93862.1 - 0.34 10.3 3.9 0.52 9.7 3.9 1.2 1 0 0 1 1 1 0 SDA1 Transthyretin PF00576.21 ORY93863.1 - 3e-37 127.7 0.0 3.3e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family DctA-YdbH PF11739.8 ORY93863.1 - 0.2 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Dicarboxylate transport GRASP55_65 PF04495.14 ORY93865.1 - 1.1e-31 109.9 0.0 1.7e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Endostatin PF06482.11 ORY93865.1 - 0.11 11.9 3.5 0.12 11.8 3.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Plasmodium_Vir PF05795.11 ORY93865.1 - 1.6 8.0 3.9 1.8 7.9 3.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2052 PF09747.9 ORY93865.1 - 1.7 8.7 13.8 2.4 8.2 13.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DIL PF01843.19 ORY93866.1 - 2.3e-24 85.7 5.1 2.3e-24 85.7 5.1 2.1 2 0 0 2 2 2 1 DIL domain Oxysterol_BP PF01237.18 ORY93867.1 - 5.2e-70 236.2 2.4 7.4e-68 229.1 2.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PRONE PF03759.13 ORY93867.1 - 0.24 10.2 2.3 0.33 9.7 2.3 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) zf-C2H2_4 PF13894.6 ORY93868.1 - 2.7e-06 27.8 23.5 0.3 12.0 0.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY93868.1 - 4.9e-06 26.7 22.4 0.033 14.6 0.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 ORY93868.1 - 6.2e-05 23.2 19.8 0.004 17.4 6.8 2.9 2 2 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 ORY93868.1 - 0.0033 18.0 11.9 2.4 8.9 0.3 4.1 2 2 2 4 4 4 1 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 ORY93868.1 - 0.0036 18.0 6.3 0.18 12.5 0.5 2.2 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 ORY93868.1 - 0.004 17.5 11.3 0.096 13.0 0.2 3.4 1 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 ORY93868.1 - 0.0048 17.5 3.9 1.4 9.7 0.3 2.7 1 1 1 2 2 2 2 Protein of unknown function (FYDLN_acid) CpXC PF14353.6 ORY93868.1 - 0.0091 16.0 8.2 0.01 15.9 2.1 2.5 1 1 1 2 2 2 1 CpXC protein zf-H2C2_2 PF13465.6 ORY93868.1 - 0.018 15.4 22.5 1.3 9.5 0.0 5.7 6 0 0 6 6 6 0 Zinc-finger double domain Zn-C2H2_12 PF18112.1 ORY93868.1 - 0.1 13.1 8.6 0.25 11.8 0.2 3.0 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 ORY93868.1 - 0.12 12.3 7.0 1.5 8.7 0.2 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 ORY93868.1 - 0.23 11.5 14.2 13 5.9 2.8 4.1 3 1 1 4 4 4 0 BED zinc finger zf-met PF12874.7 ORY93868.1 - 0.26 11.7 3.3 1.7 9.1 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 ORY93868.1 - 0.36 11.0 5.0 0.2 11.8 0.5 2.1 1 1 0 2 2 2 0 Aberrant zinc-finger FMN_red PF03358.15 ORY93869.1 - 1.7e-10 40.9 0.1 1.7e-10 40.9 0.1 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY93869.1 - 8.4e-05 22.4 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ORY93870.1 - 5.8e-13 48.9 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY93870.1 - 0.00021 21.1 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold RhoGEF PF00621.20 ORY93871.1 - 2.2e-14 54.1 0.3 8.2e-14 52.2 0.0 2.1 3 0 0 3 3 3 1 RhoGEF domain EF-G-binding_N PF07299.11 ORY93871.1 - 0.0055 17.2 0.2 1.7 9.2 0.1 3.0 2 0 0 2 2 2 2 Elongation factor G-binding protein, N-terminal Thymidylate_kin PF02223.17 ORY93872.1 - 5.6e-48 163.1 0.0 6.4e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_22 PF13401.6 ORY93872.1 - 0.002 18.4 0.0 0.0049 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORY93872.1 - 0.011 16.0 0.1 0.018 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY93872.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 ORY93872.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 ORY93872.1 - 0.043 14.2 0.1 0.3 11.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain Tetraspanin PF00335.20 ORY93873.1 - 6.3e-13 49.0 12.9 8.8e-13 48.5 12.9 1.2 1 0 0 1 1 1 1 Tetraspanin family Bac_export_2 PF01312.19 ORY93873.1 - 1.5 8.0 2.9 20 4.2 3.6 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family COPI_assoc PF08507.10 ORY93874.1 - 5.1e-17 62.1 8.0 6.7e-17 61.8 8.0 1.1 1 0 0 1 1 1 1 COPI associated protein SPC12 PF06645.13 ORY93874.1 - 7.5 6.7 8.5 1.5 8.9 4.1 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Herpes_LMP1 PF05297.11 ORY93874.1 - 9.2 5.3 8.6 12 5.0 8.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MMS1_N PF10433.9 ORY93875.1 - 4e-52 177.5 0.0 7.6e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY93875.1 - 6.1e-35 121.1 0.0 3.2e-34 118.7 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region Velvet PF11754.8 ORY93876.1 - 2.5e-52 178.3 4.0 1.3e-36 126.9 0.2 3.1 2 1 1 3 3 3 2 Velvet factor EF-hand_1 PF00036.32 ORY93877.1 - 1.5e-12 46.1 1.9 2.2e-05 23.7 0.5 3.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 ORY93877.1 - 2.3e-12 47.2 2.8 1.1e-11 45.0 1.8 2.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY93877.1 - 2.4e-11 42.6 0.2 0.00022 20.5 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY93877.1 - 1.9e-10 39.8 1.8 0.00033 20.3 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY93877.1 - 0.00019 21.7 0.2 0.12 12.6 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY93877.1 - 0.0013 18.7 0.5 0.071 13.1 0.2 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 ORY93877.1 - 0.017 14.9 6.3 0.071 13.0 0.9 3.1 4 0 0 4 4 4 0 EF-hand domain pair SNAP PF14938.6 ORY93878.1 - 1.2e-27 97.1 9.5 1.8e-27 96.5 9.5 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 ORY93878.1 - 4.6e-06 26.8 6.8 0.00049 20.3 0.6 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 ORY93878.1 - 9.2e-05 22.4 12.2 0.096 12.8 0.6 4.5 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 ORY93878.1 - 0.0021 17.5 4.4 0.0058 16.0 4.2 1.7 1 1 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 ORY93878.1 - 0.019 15.8 7.5 13 7.0 0.2 5.2 4 3 4 8 8 7 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 ORY93878.1 - 0.058 12.5 4.7 0.12 11.5 0.3 2.3 1 1 1 2 2 2 0 Spatacsin C-terminus UPF0449 PF15136.6 ORY93878.1 - 0.096 13.2 6.2 7.9 7.0 0.1 3.7 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 ACT_7 PF13840.6 ORY93878.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 ACT domain TPR_8 PF13181.6 ORY93878.1 - 0.43 10.9 7.0 10 6.6 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY93878.1 - 0.51 10.6 8.0 23 5.4 0.1 4.8 3 3 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY93878.1 - 0.52 10.2 9.5 25 4.9 0.4 4.8 4 3 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY93878.1 - 1.7 8.4 6.9 18 5.1 0.1 4.5 4 1 1 5 5 5 0 TPR repeat TPR_3 PF07720.12 ORY93878.1 - 1.9 8.5 7.7 23 5.1 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY93878.1 - 5.6 7.8 10.8 36 5.3 1.0 4.9 4 1 1 5 5 4 0 Tetratricopeptide repeat DHR-2 PF06920.13 ORY93879.1 - 5.4e-100 335.5 2.2 1.8e-99 333.8 2.2 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 ORY93879.1 - 1.5e-88 297.2 2.7 2.5e-88 296.5 0.0 2.8 2 1 0 2 2 2 1 DOCK N-terminus DOCK-C2 PF14429.6 ORY93879.1 - 2.8e-41 141.5 0.2 8.2e-41 140.0 0.2 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SUIM_assoc PF16619.5 ORY93879.1 - 0.27 11.3 14.5 0.1 12.7 2.3 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_16 PF10294.9 ORY93880.1 - 3.9e-32 111.4 0.8 1.1e-31 110.0 0.8 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY93880.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY93880.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY93880.1 - 0.001 18.5 0.9 0.0028 17.1 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ORY93880.1 - 0.049 13.4 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Lipase_GDSL PF00657.22 ORY93881.1 - 4.4e-07 30.1 0.1 6.7e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY93881.1 - 6e-06 26.8 0.3 1.1e-05 26.0 0.3 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Nudix_hydro PF18290.1 ORY93881.1 - 0.013 15.4 0.2 0.055 13.5 0.0 2.0 2 0 0 2 2 2 0 Nudix hydrolase domain Ribosomal_L36e PF01158.18 ORY93883.1 - 9.9e-40 134.7 6.1 1.1e-39 134.5 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2207 PF09972.9 ORY93883.1 - 0.15 10.8 0.1 0.17 10.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RRM_1 PF00076.22 ORY93884.1 - 2.3e-11 43.3 0.0 5.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 ORY93885.1 - 1.2e-32 113.1 0.4 4.8e-32 111.1 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY93885.1 - 2.8e-25 88.8 0.5 1.8e-23 83.0 0.1 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY93885.1 - 8.1e-08 32.5 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY93885.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain DLH PF01738.18 ORY93886.1 - 1.8e-35 122.5 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.9 ORY93886.1 - 0.0043 16.2 0.1 0.006 15.7 0.1 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 DHHA1 PF02272.19 ORY93886.1 - 0.0069 16.8 0.2 0.013 15.9 0.2 1.4 1 0 0 1 1 1 1 DHHA1 domain Abhydrolase_2 PF02230.16 ORY93886.1 - 0.021 14.7 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ORY93886.1 - 0.024 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY93886.1 - 0.038 13.5 0.3 1 8.8 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family DnaJ PF00226.31 ORY93889.1 - 1.2e-21 76.6 3.2 3.6e-20 71.9 1.3 2.6 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 ORY93889.1 - 0.021 14.6 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alpha_E3_glycop PF01563.16 ORY93889.1 - 0.11 12.6 0.3 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Alphavirus E3 glycoprotein TMIE PF16038.5 ORY93889.1 - 2.3 8.1 5.4 8.5 6.3 5.4 1.9 1 0 0 1 1 1 0 TMIE protein CPP1-like PF11833.8 ORY93889.1 - 5.9 6.5 9.8 1.2 8.7 6.0 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Cwf_Cwc_15 PF04889.12 ORY93890.1 - 0.26 11.0 6.4 0.019 14.7 1.2 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein COPI_assoc PF08507.10 ORY93891.1 - 6.2e-28 97.5 10.7 7.7e-28 97.1 10.7 1.0 1 0 0 1 1 1 1 COPI associated protein DUF373 PF04123.13 ORY93891.1 - 0.36 10.2 6.9 0.46 9.9 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2583 PF10762.9 ORY93891.1 - 0.84 10.1 4.0 7 7.1 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Cg6151-P PF10233.9 ORY93891.1 - 2 8.7 15.9 8.1 6.8 15.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DuoxA PF10204.9 ORY93891.1 - 4.2 6.3 8.3 3 6.8 7.1 1.3 1 1 0 1 1 1 0 Dual oxidase maturation factor zf-A20 PF01754.16 ORY93892.1 - 1.4e-09 37.7 7.4 1.4e-09 37.7 7.4 1.9 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 ORY93892.1 - 5.2e-07 29.7 8.6 5.2e-07 29.7 8.6 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger TFIIA PF03153.13 ORY93892.1 - 0.056 13.4 15.5 0.075 13.0 15.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 ORY93892.1 - 0.056 12.3 4.7 0.054 12.4 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mitofilin PF09731.9 ORY93892.1 - 0.057 12.3 5.6 0.063 12.1 5.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Spt20 PF12090.8 ORY93892.1 - 0.33 10.5 16.1 0.44 10.1 16.1 1.4 1 0 0 1 1 1 0 Spt20 family SRP-alpha_N PF04086.13 ORY93892.1 - 0.57 10.1 9.8 0.77 9.6 9.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 ORY93892.1 - 1.4 7.6 13.4 1.5 7.4 13.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EPL1 PF10513.9 ORY93892.1 - 1.4 9.3 9.3 1.8 8.9 9.3 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Hydin_ADK PF17213.3 ORY93892.1 - 1.5 9.1 7.2 2.2 8.5 7.2 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Zip PF02535.22 ORY93892.1 - 1.5 7.9 3.1 2 7.6 3.1 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 ORY93892.1 - 3 7.3 12.0 3.8 7.0 12.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 ORY93892.1 - 4.7 7.0 15.5 6.1 6.7 15.5 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 ORY93892.1 - 6.1 5.3 8.0 6.6 5.2 8.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF3917 PF13055.6 ORY93893.1 - 0.96 9.9 5.5 0.93 10.0 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3917) Ribosomal_S13_N PF08069.12 ORY93894.1 - 1e-31 108.7 0.3 1.8e-31 107.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORY93894.1 - 1.9e-14 53.6 0.4 2.7e-14 53.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PolyA_pol PF01743.20 ORY93895.1 - 7e-30 104.1 0.2 1.3e-29 103.1 0.2 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ORY93895.1 - 7.2e-10 38.5 0.0 1.9e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF5333 PF17267.2 ORY93895.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5333) WD40 PF00400.32 ORY93896.1 - 4.2e-43 144.5 13.5 1.7e-05 25.5 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY93896.1 - 8.3e-15 54.9 1.9 0.001 19.3 0.1 5.8 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY93896.1 - 4.1e-06 26.0 0.2 1.6 7.6 0.0 4.6 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY93896.1 - 0.0025 16.4 0.7 0.007 14.9 0.2 1.9 2 1 1 3 3 3 1 Cytochrome D1 heme domain Frtz PF11768.8 ORY93896.1 - 0.048 12.0 0.0 2.6 6.3 0.0 2.6 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 ORY93896.1 - 0.12 11.0 1.8 20 3.7 0.0 3.7 2 1 3 5 5 5 0 Nucleoporin Nup120/160 Ribosomal_L50 PF10501.9 ORY93897.1 - 5.4e-05 23.3 0.0 8.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S BAG PF02179.16 ORY93898.1 - 2.4e-15 56.7 0.4 4e-15 56.0 0.4 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 ORY93898.1 - 1.8e-07 30.8 0.0 7.4e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY93898.1 - 2.1e-05 24.9 0.0 6.7e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.8 ORY93898.1 - 0.0031 17.7 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 TUG ubiquitin-like domain Prot_ATP_OB_N PF17758.1 ORY93898.1 - 0.051 13.2 0.0 5.8 6.7 0.0 2.7 3 0 0 3 3 3 0 Proteasomal ATPase OB N-terminal domain Ribosomal_L5_C PF00673.21 ORY93900.1 - 7.7e-22 77.3 0.0 1.2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY93900.1 - 2.6e-20 72.5 0.0 8.4e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_S8e PF01201.22 ORY93901.1 - 9.5e-55 184.5 0.8 1.1e-54 184.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e MARVEL PF01284.23 ORY93903.1 - 1.2e-07 31.8 2.7 1.7e-07 31.4 2.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 ORY93903.1 - 0.0054 16.5 0.1 0.007 16.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF588) TPR_2 PF07719.17 ORY93904.1 - 0.00022 21.1 1.0 0.51 10.6 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 ORY93904.1 - 0.00095 19.0 0.7 0.0021 17.9 0.7 1.6 1 0 0 1 1 1 1 F-box-like TPR_7 PF13176.6 ORY93904.1 - 0.0057 16.6 0.4 0.044 13.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY93904.1 - 0.033 14.8 0.0 0.069 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY93904.1 - 0.041 14.2 0.0 0.53 10.6 0.0 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat F-box PF00646.33 ORY93904.1 - 0.044 13.7 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 F-box domain TPR_19 PF14559.6 ORY93904.1 - 0.069 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.28 ORY93905.1 - 6.6e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 SET domain GDA1_CD39 PF01150.17 ORY93906.1 - 2.9e-106 355.7 0.0 4e-106 355.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 ORY93906.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family MIP PF00230.20 ORY93907.1 - 1.2e-44 152.8 8.5 1.3e-44 152.6 8.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sulfate_transp PF00916.20 ORY93908.1 - 4.3e-120 400.9 15.3 5.4e-120 400.6 15.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY93908.1 - 1.1e-11 44.4 0.0 2.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY93908.1 - 0.00018 21.9 1.4 0.00018 21.9 1.4 2.8 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORY93908.1 - 0.00031 21.0 0.8 0.00082 19.7 0.8 1.7 1 0 0 1 1 1 1 STAS domain DUF4521 PF15021.6 ORY93908.1 - 0.095 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Ndc1_Nup PF09531.10 ORY93909.1 - 3e-73 247.6 2.7 3.8e-73 247.2 2.7 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TMEM247 PF15444.6 ORY93910.1 - 0.0024 18.0 2.2 0.0024 18.0 2.2 2.4 2 0 0 2 2 2 1 Transmembrane protein 247 zf-C3HC4_3 PF13920.6 ORY93910.1 - 0.0038 17.1 8.7 0.0062 16.4 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MIF4G_like_2 PF09090.11 ORY93910.1 - 0.72 9.3 7.3 1.5 8.3 7.3 1.5 1 0 0 1 1 1 0 MIF4G like MAT1 PF06391.13 ORY93910.1 - 1.4 8.7 18.9 2.8 7.7 18.9 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CDC45 PF02724.14 ORY93910.1 - 2.8 6.1 15.7 4.7 5.4 15.7 1.4 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORY93910.1 - 5.4 6.7 17.1 16 5.2 17.1 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zn_ribbon_SprT PF17283.2 ORY93911.1 - 0.013 15.4 1.2 0.78 9.7 0.1 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain GFA PF04828.14 ORY93911.1 - 0.076 13.4 0.0 0.14 12.6 0.0 1.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Pre-PUA PF17832.1 ORY93912.1 - 1.9e-27 95.8 0.1 2.8e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 ORY93912.1 - 8.8e-17 60.8 0.0 1.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 ORY93912.1 - 0.17 12.2 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF3818 PF12825.7 ORY93913.1 - 3.5e-94 315.6 0.1 6.8e-94 314.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORY93913.1 - 4e-14 52.7 3.3 3.2e-13 49.8 3.3 2.4 1 1 0 1 1 1 1 PX-associated PX PF00787.24 ORY93913.1 - 2.1e-11 43.8 0.1 5.7e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 PX domain FTA4 PF13093.6 ORY93913.1 - 0.071 13.0 2.1 0.8 9.6 0.1 2.8 3 0 0 3 3 3 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Myb_DNA-bind_6 PF13921.6 ORY93914.1 - 0.015 15.6 0.3 0.027 14.7 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY93914.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_23 PF13384.6 ORY93914.1 - 0.064 13.1 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Endomucin PF07010.12 ORY93914.1 - 0.94 9.4 8.9 1.2 9.0 8.9 1.1 1 0 0 1 1 1 0 Endomucin NIF PF03031.18 ORY93915.1 - 2.4e-25 89.1 0.3 4.2e-25 88.3 0.3 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Methyltransf_23 PF13489.6 ORY93916.1 - 9.5e-18 64.6 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93916.1 - 1.3e-15 57.9 0.0 4.4e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY93916.1 - 3.2e-14 53.4 0.0 1.2e-13 51.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY93916.1 - 6e-11 42.9 0.0 1.5e-10 41.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY93916.1 - 1.3e-09 38.0 0.0 2.8e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORY93916.1 - 3.6e-05 23.1 0.0 0.084 12.0 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 ORY93916.1 - 0.00037 19.9 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY93916.1 - 0.0004 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 ORY93916.1 - 0.0041 16.6 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain TPMT PF05724.11 ORY93916.1 - 0.0096 15.6 1.3 0.046 13.4 0.0 2.4 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.6 ORY93916.1 - 0.026 15.6 0.0 0.068 14.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Pex14_N PF04695.13 ORY93916.1 - 0.067 13.8 0.5 0.74 10.5 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_4 PF02390.17 ORY93916.1 - 0.09 12.2 0.1 3.4 7.1 0.0 2.8 3 0 0 3 3 3 0 Putative methyltransferase DUF3298 PF11738.8 ORY93916.1 - 0.13 13.3 1.4 3 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Homeobox_KN PF05920.11 ORY93917.1 - 2.8e-09 36.7 1.6 5.5e-09 35.8 1.6 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY93917.1 - 5e-09 35.9 4.9 8.8e-09 35.1 4.9 1.4 1 0 0 1 1 1 1 Homeodomain HTH_28 PF13518.6 ORY93917.1 - 0.048 13.8 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 ORY93917.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pkinase PF00069.25 ORY93918.1 - 1.7e-51 175.1 0.0 2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93918.1 - 4.4e-27 95.0 0.0 5.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY93918.1 - 0.00013 20.9 0.0 0.00018 20.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY93918.1 - 0.0033 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY93918.1 - 0.0085 16.0 0.0 0.31 10.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY93918.1 - 0.013 14.4 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 ORY93918.1 - 0.024 14.2 0.3 0.035 13.7 0.3 1.2 1 0 0 1 1 1 0 RIO1 family EF-hand_1 PF00036.32 ORY93919.1 - 6.6e-39 128.6 14.6 3.7e-09 35.5 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY93919.1 - 7.5e-31 106.4 3.8 7.7e-16 58.3 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY93919.1 - 3.8e-29 98.1 9.2 2.2e-08 33.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORY93919.1 - 1.6e-26 90.6 15.9 3.2e-08 32.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY93919.1 - 1.6e-23 82.3 12.8 1.4e-12 47.3 0.2 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 ORY93919.1 - 1.5e-11 44.4 0.0 3.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY93919.1 - 1.8e-08 34.7 0.1 0.0028 18.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY93919.1 - 2.3e-07 30.7 0.7 0.019 14.9 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 ORY93919.1 - 0.0046 15.6 0.0 0.0049 15.5 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) UPF0154 PF03672.13 ORY93919.1 - 0.0048 16.9 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) dCache_2 PF08269.11 ORY93919.1 - 0.014 14.6 0.1 2.5 7.2 0.0 2.1 1 1 1 2 2 2 0 Cache domain Dockerin_1 PF00404.18 ORY93919.1 - 0.015 15.5 4.2 0.93 9.7 0.2 3.0 1 1 2 3 3 3 0 Dockerin type I domain SurA_N_3 PF13624.6 ORY93919.1 - 0.039 13.7 0.2 0.23 11.3 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 ORY93919.1 - 0.059 12.0 0.0 2.5 6.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) PMBR PF09373.10 ORY93919.1 - 0.063 13.5 0.0 2.6 8.4 0.0 2.8 3 0 0 3 3 2 0 Pseudomurein-binding repeat SurA_N_2 PF13623.6 ORY93919.1 - 0.063 13.1 0.6 1.9 8.3 0.0 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 ORY93919.1 - 0.074 13.2 0.1 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 Transcription factor MotA, activation domain EF-hand_11 PF08976.11 ORY93919.1 - 0.12 13.3 0.0 0.82 10.6 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain Excalibur PF05901.11 ORY93919.1 - 0.24 12.0 2.0 7.2 7.3 0.0 3.5 4 0 0 4 4 4 0 Excalibur calcium-binding domain OGG_N PF07934.12 ORY93920.1 - 5.3e-26 91.1 0.1 9.8e-26 90.2 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 ORY93920.1 - 9e-18 64.7 0.0 1.7e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY93920.1 - 0.052 13.4 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pkinase PF00069.25 ORY93921.1 - 2.5e-59 200.8 0.0 3.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93921.1 - 8.6e-31 107.2 0.0 1.2e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORY93921.1 - 1.4e-12 47.8 0.0 2.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 ORY93921.1 - 0.00034 19.5 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY93921.1 - 0.0095 15.3 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY93921.1 - 0.017 14.1 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY93921.1 - 0.036 14.0 0.0 0.7 9.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORY93921.1 - 0.048 13.3 0.2 0.084 12.5 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_17 PF00332.18 ORY93922.1 - 4.8e-08 33.0 0.3 1.6e-07 31.3 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 60KD_IMP PF02096.20 ORY93923.1 - 9.7e-18 64.6 1.2 7.6e-17 61.7 1.2 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein Cob_adeno_trans PF01923.18 ORY93924.1 - 6.2e-50 169.6 0.0 7e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase CitMHS PF03600.16 ORY93925.1 - 2.9e-32 112.1 61.4 2.8e-26 92.4 36.9 2.4 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 ORY93925.1 - 4.5e-30 105.8 10.4 5e-14 53.0 1.4 3.2 1 1 2 3 3 3 3 SPX domain Na_sulph_symp PF00939.19 ORY93925.1 - 1.4e-29 103.5 36.1 1.9e-29 103.1 36.1 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Saf_2TM PF18303.1 ORY93925.1 - 0.14 11.8 1.9 0.61 9.7 0.1 3.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Prenyltransf PF01255.19 ORY93926.1 - 8.1e-73 244.6 0.0 9.9e-73 244.4 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Activator-TraM PF11657.8 ORY93926.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional activator TraM DUF2787 PF10980.8 ORY93926.1 - 0.1 12.8 0.3 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) NIF PF03031.18 ORY93928.1 - 3.3e-27 95.2 0.1 4.4e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_tranf_2_3 PF13641.6 ORY93929.1 - 1.4e-27 97.1 0.0 1.8e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY93929.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY93929.1 - 9.1e-07 28.5 0.3 1.1e-05 25.0 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 SLIDE PF09111.10 ORY93929.1 - 0.2 11.7 5.6 3.2 7.8 0.1 2.9 3 0 0 3 3 3 0 SLIDE Peptidase_M24 PF00557.24 ORY93931.1 - 5.5e-53 179.8 0.0 7.2e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY93931.1 - 4.5e-18 65.2 0.0 8.6e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TTKRSYEDQ PF10212.9 ORY93932.1 - 3.9e-14 52.6 15.3 4.6e-14 52.3 15.3 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein BST2 PF16716.5 ORY93932.1 - 0.013 16.1 10.8 0.013 16.1 10.8 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YceG_bac PF14266.6 ORY93932.1 - 0.077 11.9 3.4 0.11 11.4 3.4 1.2 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' DUF1640 PF07798.11 ORY93932.1 - 0.48 10.4 15.6 0.68 10.0 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) IFT57 PF10498.9 ORY93932.1 - 0.61 9.0 20.8 0.7 8.8 20.8 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Dynactin_p62 PF05502.13 ORY93932.1 - 1.8 7.2 15.9 0.12 11.2 9.8 1.6 1 1 1 2 2 2 0 Dynactin p62 family Zip PF02535.22 ORY93932.1 - 5.1 6.2 5.2 5.5 6.1 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 ORY93932.1 - 9.5 6.2 12.9 3.2 7.8 10.2 1.5 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MPS2 PF17060.5 ORY93933.1 - 0.09 12.0 4.8 0.1 11.8 4.8 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 DLP_helical PF18709.1 ORY93933.1 - 0.22 10.7 5.3 0.075 12.2 2.5 1.6 2 0 0 2 2 2 0 Dynamin-like helical domain TPR_MLP1_2 PF07926.12 ORY93933.1 - 0.36 10.9 15.2 0.15 12.1 6.1 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 ORY93933.1 - 0.52 9.6 4.9 0.88 8.9 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ntox1 PF15500.6 ORY93933.1 - 0.71 10.3 3.8 0.35 11.3 0.3 2.1 2 1 0 2 2 2 0 Putative RNase-like toxin, toxin_1 Atg14 PF10186.9 ORY93933.1 - 0.8 8.7 8.6 2 7.4 8.6 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 ORY93933.1 - 1.1 9.4 15.8 6.5 7.0 1.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 ORY93933.1 - 6.8 6.9 12.3 1.6 8.9 4.1 3.3 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 Conotoxin PF02950.17 ORY93934.1 - 0.02 15.9 0.6 0.039 15.0 0.6 1.5 1 1 0 1 1 1 0 Conotoxin Granulin PF00396.18 ORY93934.1 - 0.23 11.8 4.5 0.18 12.2 2.5 1.8 2 0 0 2 2 2 0 Granulin ODC_AZ PF02100.17 ORY93935.1 - 2.8e-12 46.6 0.0 4.4e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme Thiolase_N PF00108.23 ORY93936.1 - 1.2e-18 67.4 0.1 4.2e-17 62.4 0.1 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY93936.1 - 5.3e-11 42.2 0.0 1.4e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 ORY93936.1 - 0.00021 21.3 0.2 0.028 14.4 0.0 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 ORY93936.1 - 0.0014 18.5 0.4 0.14 12.1 0.2 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ORY93936.1 - 0.0033 17.1 4.8 0.053 13.1 1.0 2.5 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 ORY93936.1 - 0.012 14.3 0.5 0.11 11.1 0.1 2.1 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) LSM PF01423.22 ORY93937.1 - 5.2e-05 22.9 0.1 0.0001 21.9 0.0 1.5 2 0 0 2 2 2 1 LSM domain LSM14 PF12701.7 ORY93937.1 - 0.0033 17.5 0.2 0.032 14.3 0.2 2.2 1 1 0 1 1 1 1 Scd6-like Sm domain Coilin_N PF15862.5 ORY93937.1 - 0.2 11.5 4.4 0.26 11.1 0.6 2.0 2 0 0 2 2 2 0 Coilin N-terminus TFIIA PF03153.13 ORY93937.1 - 0.58 10.1 19.5 0.74 9.7 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 ORY93937.1 - 0.96 9.6 24.5 3.4 7.8 9.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 ORY93937.1 - 1.9 8.4 15.1 2.4 8.1 15.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 ORY93937.1 - 7.6 4.7 18.6 8.1 4.6 18.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YjeF_N PF03853.15 ORY93938.1 - 5.4e-25 88.2 0.1 1.2e-24 87.1 0.1 1.6 1 0 0 1 1 1 1 YjeF-related protein N-terminus SabA_adhesion PF18304.1 ORY93938.1 - 0.29 10.3 6.2 0.3 10.3 5.4 1.4 1 1 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Adaptin_binding PF10199.9 ORY93938.1 - 4.9 7.8 21.0 5.5e+03 -2.1 21.0 2.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 UPRTase PF14681.6 ORY93939.1 - 5.5e-80 267.7 0.0 6.2e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY93939.1 - 0.03 13.8 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain SAP PF02037.27 ORY93940.1 - 2.5e-10 39.8 0.1 4.2e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 SAP domain TBP PF00352.21 ORY93941.1 - 3.4e-50 167.9 0.1 2e-32 111.0 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 ORY93941.1 - 7.2e-05 22.8 0.0 0.29 11.3 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) SLC35F PF06027.12 ORY93942.1 - 1.1e-96 323.9 22.4 1.3e-96 323.7 22.4 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 ORY93942.1 - 3.2e-09 37.1 28.5 1.2e-05 25.5 10.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 ORY93942.1 - 2.6e-07 29.9 5.4 2.6e-07 29.9 5.4 1.6 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Spermine_synth PF01564.17 ORY93943.1 - 6.8e-63 211.5 0.1 9.8e-63 211.0 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ORY93943.1 - 9.7e-26 89.4 0.4 4e-25 87.4 0.2 2.0 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Methyltransf_PK PF05891.12 ORY93943.1 - 0.00059 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORY93943.1 - 0.00072 20.2 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93943.1 - 0.032 15.0 0.1 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF43 PF01861.16 ORY93943.1 - 0.046 12.9 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Urb2 PF10441.9 ORY93945.1 - 2.9e-34 118.8 8.4 1.2e-33 116.8 0.1 3.3 2 2 1 3 3 3 2 Urb2/Npa2 family DNA_pol_phi PF04931.13 ORY93945.1 - 0.017 13.3 0.3 0.035 12.2 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase phi Sec23_trunk PF04811.15 ORY93946.1 - 1.4e-45 155.8 0.0 9.5e-34 117.0 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORY93946.1 - 1.3e-18 67.5 0.0 2.4e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY93946.1 - 2.6e-14 53.0 3.0 5e-14 52.1 3.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 ORY93946.1 - 2.7e-14 52.8 0.3 9.3e-14 51.1 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 ORY93946.1 - 8.7e-07 28.8 0.0 3e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORY93946.1 - 0.011 15.1 0.2 0.026 13.9 0.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3984 PF13136.6 ORY93946.1 - 0.74 9.2 14.3 1.1 8.6 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4210 PF13915.6 ORY93947.1 - 5.2e-32 110.3 0.0 1.7e-31 108.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 ORY93947.1 - 5.4e-13 48.9 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis ATG13 PF10033.9 ORY93947.1 - 0.0005 19.8 0.6 0.0011 18.7 0.0 1.9 2 1 0 2 2 2 1 Autophagy-related protein 13 E_Pc_C PF06752.12 ORY93947.1 - 2.1 8.4 16.6 0.043 13.9 9.8 1.7 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Arf PF00025.21 ORY93948.1 - 1.4e-17 63.7 0.1 3.1e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORY93948.1 - 3.3e-08 33.1 0.3 2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit Roc PF08477.13 ORY93948.1 - 3.1e-06 27.4 0.1 5.7e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY93948.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ORY93948.1 - 0.002 18.6 0.0 0.0093 16.5 0.0 2.1 3 0 0 3 3 2 1 ABC transporter Ploopntkinase3 PF18751.1 ORY93948.1 - 0.0025 17.8 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 SRPRB PF09439.10 ORY93948.1 - 0.0028 17.1 0.2 0.014 14.8 0.2 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY93948.1 - 0.0047 16.5 0.1 0.0084 15.7 0.1 1.4 1 0 0 1 1 1 1 Ras family NACHT PF05729.12 ORY93948.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 ORY93948.1 - 0.0097 15.6 0.0 0.056 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Spectrin_like PF18373.1 ORY93948.1 - 0.014 15.5 0.1 0.13 12.3 0.0 2.6 3 0 0 3 3 3 0 Spectrin like domain Gtr1_RagA PF04670.12 ORY93948.1 - 0.015 14.7 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_30 PF13604.6 ORY93948.1 - 0.018 14.7 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY93948.1 - 0.021 14.8 0.1 0.25 11.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY93948.1 - 0.028 14.6 0.1 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 ORY93948.1 - 0.029 13.6 0.0 0.077 12.2 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 ORY93948.1 - 0.032 14.5 0.1 0.1 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF440 PF04269.12 ORY93948.1 - 0.042 14.1 0.1 0.099 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF440 AAA_5 PF07728.14 ORY93948.1 - 0.045 13.8 0.0 0.18 11.8 0.0 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 ORY93948.1 - 0.045 13.8 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORY93948.1 - 0.055 13.2 0.0 0.24 11.2 0.0 2.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 ORY93948.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 ORY93948.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 ORY93948.1 - 0.11 12.3 0.1 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 ORY93948.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 ORY93948.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like PF12937.7 ORY93949.1 - 2.6e-10 40.0 0.2 1.2e-09 37.9 0.2 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY93949.1 - 9.5e-06 25.4 0.1 9.5e-06 25.4 0.1 3.1 4 0 0 4 4 4 1 F-box domain DEAD PF00270.29 ORY93950.1 - 2.1e-50 170.9 0.0 3.6e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY93950.1 - 5.4e-30 104.0 0.0 1.1e-27 96.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY93950.1 - 2e-05 24.7 0.0 5.3e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4743 PF15916.5 ORY93952.1 - 2.9e-17 62.8 0.0 4.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 ORY93952.1 - 2.1e-09 37.5 0.1 4.1e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1408 PF07193.11 ORY93952.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) CNH PF00780.22 ORY93953.1 - 1.9e-05 24.4 0.0 0.077 12.6 0.0 2.3 2 0 0 2 2 2 2 CNH domain MaoC_dehydratas PF01575.19 ORY93954.1 - 2.5e-26 91.6 0.0 4.4e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY93954.1 - 0.015 15.5 0.0 0.68 10.1 0.0 2.9 3 1 0 3 3 3 0 N-terminal half of MaoC dehydratase DUF2808 PF10989.8 ORY93954.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) UCH PF00443.29 ORY93955.1 - 1.4e-46 159.1 0.1 2e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY93955.1 - 3.3e-07 30.2 5.0 5.3e-06 26.3 5.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3287 PF11690.8 ORY93955.1 - 2.4 7.9 6.6 1.2 8.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Presenilin PF01080.17 ORY93956.1 - 1.4 7.7 3.1 1.5 7.5 3.1 1.0 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 ORY93956.1 - 6.8 7.3 14.0 8.7 7.0 14.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nfu_N PF08712.11 ORY93957.1 - 3e-32 110.5 0.1 1.3e-31 108.4 0.0 2.1 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORY93957.1 - 2.9e-28 97.8 0.2 4.9e-28 97.1 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 ORY93957.1 - 0.0068 16.5 0.8 0.019 15.1 0.4 1.9 2 0 0 2 2 2 1 Bacterial membrane-spanning protein N-terminus Uso1_p115_head PF04869.14 ORY93958.1 - 1.2e-74 251.3 1.6 1.5e-74 251.0 0.0 2.0 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 ORY93958.1 - 4.2e-14 53.0 32.1 4.2e-14 53.0 32.1 2.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region FPP PF05911.11 ORY93958.1 - 5e-06 25.0 24.8 8.4e-06 24.3 24.8 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Arm_vescicular PF18770.1 ORY93958.1 - 1.2e-05 25.2 0.0 3.9e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Fib_alpha PF08702.10 ORY93958.1 - 0.0015 18.7 4.0 0.0015 18.7 4.0 2.7 2 1 1 3 3 2 1 Fibrinogen alpha/beta chain family GAS PF13851.6 ORY93958.1 - 0.017 14.5 33.1 0.022 14.1 24.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atx10homo_assoc PF09759.9 ORY93958.1 - 0.022 14.8 6.0 2.2 8.3 0.0 4.3 5 0 0 5 5 4 0 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 ORY93958.1 - 0.022 14.9 0.6 1.3 9.2 0.1 3.3 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Lebercilin PF15619.6 ORY93958.1 - 0.037 13.7 28.0 0.027 14.1 18.1 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.22 ORY93958.1 - 0.063 13.5 21.5 0.062 13.5 17.8 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.9 ORY93958.1 - 0.11 11.0 18.2 0.15 10.5 18.2 1.1 1 0 0 1 1 1 0 Macoilin family TMF_TATA_bd PF12325.8 ORY93958.1 - 0.14 12.4 27.8 0.07 13.4 18.5 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 ORY93958.1 - 0.16 11.5 34.9 0.16 11.5 33.1 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FapA PF03961.13 ORY93958.1 - 0.16 10.5 11.8 0.29 9.7 11.8 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cnd1 PF12717.7 ORY93958.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.8 3 0 0 3 3 2 0 non-SMC mitotic condensation complex subunit 1 DUF4201 PF13870.6 ORY93958.1 - 0.21 11.3 23.2 0.13 12.0 18.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Mod_r PF07200.13 ORY93958.1 - 0.33 11.1 29.2 0.19 11.8 2.9 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Noelin-1 PF12308.8 ORY93958.1 - 0.47 10.5 5.7 1.6 8.8 5.7 1.9 1 0 0 1 1 1 0 Neurogenesis glycoprotein Fez1 PF06818.15 ORY93958.1 - 0.54 10.7 29.1 0.54 10.7 27.1 1.9 1 1 1 2 2 2 0 Fez1 AAA_13 PF13166.6 ORY93958.1 - 0.8 8.3 20.8 1.1 7.8 20.8 1.2 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 ORY93958.1 - 0.91 9.0 15.0 1.6 8.2 15.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 ORY93958.1 - 1 7.8 7.7 1.7 7.1 7.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 ORY93958.1 - 1.5 6.7 15.8 2.7 5.8 15.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.8 ORY93958.1 - 2.3 5.6 28.1 3.5 5.0 28.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PI_PP_I PF18363.1 ORY93958.1 - 2.4 8.4 4.4 7 6.9 4.4 1.8 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain DUF2400 PF09674.10 ORY93958.1 - 2.5 8.0 4.8 4.9 7.1 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) zf-C4H2 PF10146.9 ORY93958.1 - 3.3 8.0 19.3 6.5 7.0 19.3 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein ATG16 PF08614.11 ORY93958.1 - 3.3 7.9 36.1 1.4 9.1 31.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KxDL PF10241.9 ORY93958.1 - 3.6 7.9 19.5 25 5.2 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein APG6_N PF17675.1 ORY93958.1 - 4 8.0 42.1 0.097 13.2 28.9 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Prominin PF05478.11 ORY93958.1 - 4.3 5.2 7.8 6.7 4.5 7.8 1.3 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 ORY93958.1 - 4.3 6.1 31.8 8.4 5.2 30.6 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 ORY93958.1 - 5.6 7.0 29.7 4.1 7.5 17.8 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5069 PF16798.5 ORY93958.1 - 6.2 7.0 7.2 0.88 9.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) HEAT PF02985.22 ORY93958.1 - 6.8 7.2 7.5 80 3.9 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat MCC-bdg_PDZ PF10506.9 ORY93958.1 - 7.3 6.7 16.2 17 5.5 8.4 2.9 2 1 1 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CHDCT2 PF08074.11 ORY93958.1 - 8.8 6.5 9.0 15 5.7 6.2 2.5 2 1 1 3 3 2 0 CHDCT2 (NUC038) domain DEAD PF00270.29 ORY93959.1 - 3.5e-44 150.6 0.0 6.2e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY93959.1 - 1.4e-30 105.9 0.0 9.3e-27 93.6 0.0 3.2 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY93959.1 - 6.6e-07 29.5 0.0 2.4e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GUCT PF08152.12 ORY93959.1 - 1e-06 28.9 0.0 4e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain CMS1 PF14617.6 ORY93959.1 - 3.8e-05 23.2 0.0 3.8e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.14 ORY93959.1 - 0.024 14.0 0.2 0.06 12.6 0.1 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_30 PF13604.6 ORY93959.1 - 0.091 12.5 0.1 0.42 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 ORY93960.1 - 2.6e-09 37.3 0.0 5.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY93960.1 - 9.6e-05 22.7 0.0 0.0012 19.2 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY93960.1 - 0.0016 18.4 0.0 0.062 13.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY93960.1 - 0.0018 18.4 0.0 0.16 12.1 0.1 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Halogen_Hydrol PF10112.9 ORY93960.1 - 0.035 14.1 0.2 2.4 8.1 0.1 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Glyco_hydro_28 PF00295.17 ORY93961.1 - 3.7e-62 210.3 9.1 5.1e-62 209.8 9.0 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Hexokinase_2 PF03727.16 ORY93962.1 - 3e-84 282.2 0.0 4.7e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY93962.1 - 2.1e-72 243.2 0.0 3.4e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Bac_DNA_binding PF00216.21 ORY93962.1 - 0.017 15.3 0.1 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial DNA-binding protein PqqD PF05402.12 ORY93962.1 - 0.072 13.4 0.2 0.19 12.1 0.2 1.7 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF3606 PF12244.8 ORY93962.1 - 0.094 12.7 0.4 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) FGGY_N PF00370.21 ORY93962.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain ABC_tran PF00005.27 ORY93963.1 - 5.8e-40 137.0 0.0 6e-21 75.4 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY93963.1 - 1.6e-16 61.0 11.1 5e-05 23.2 0.6 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY93963.1 - 3.1e-08 34.0 0.6 0.0032 17.7 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORY93963.1 - 9.2e-08 32.5 0.0 0.00086 19.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORY93963.1 - 2.2e-07 30.5 0.0 0.007 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY93963.1 - 7.9e-07 29.8 1.2 0.017 15.6 0.0 3.0 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 ORY93963.1 - 1.6e-05 25.4 1.0 0.37 11.3 0.0 4.0 3 1 1 4 4 4 1 AAA domain SMC_N PF02463.19 ORY93963.1 - 4e-05 23.2 0.1 0.8 9.1 0.1 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 ORY93963.1 - 4e-05 23.4 0.2 0.51 10.0 0.0 3.6 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_33 PF13671.6 ORY93963.1 - 7.1e-05 23.0 0.1 0.54 10.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain T2SSE PF00437.20 ORY93963.1 - 0.0001 21.5 0.0 0.053 12.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.29 ORY93963.1 - 0.00015 22.2 0.1 1.6 9.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY93963.1 - 0.00017 21.5 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY93963.1 - 0.00034 21.0 1.3 1.5 9.1 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 ORY93963.1 - 0.00035 20.3 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORY93963.1 - 0.00051 20.2 0.0 3.3 8.0 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 ORY93963.1 - 0.00057 19.6 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 ORY93963.1 - 0.00072 19.6 0.0 0.025 14.7 0.0 2.7 3 0 0 3 3 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY93963.1 - 0.00076 19.5 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.6 ORY93963.1 - 0.0014 18.6 0.0 0.37 10.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 ORY93963.1 - 0.0018 17.9 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ORY93963.1 - 0.0024 17.7 0.1 0.22 11.2 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain TsaE PF02367.17 ORY93963.1 - 0.0027 17.7 0.0 0.79 9.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase1 PF18748.1 ORY93963.1 - 0.0049 16.4 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 AAA_25 PF13481.6 ORY93963.1 - 0.0058 16.2 0.4 1.5 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 ORY93963.1 - 0.0092 15.9 0.8 5.4 6.9 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_27 PF13514.6 ORY93963.1 - 0.0097 15.5 0.1 0.31 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY93963.1 - 0.011 15.5 0.2 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 ORY93963.1 - 0.012 15.0 0.0 14 5.1 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein dNK PF01712.19 ORY93963.1 - 0.013 15.4 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase FeoB_N PF02421.18 ORY93963.1 - 0.018 14.6 0.1 5.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B ATPase_2 PF01637.18 ORY93963.1 - 0.021 14.8 0.0 5.9 6.7 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY93963.1 - 0.022 14.7 0.0 1 9.3 0.0 2.8 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.10 ORY93963.1 - 0.023 14.1 0.0 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 ORY93963.1 - 0.036 13.6 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 ORY93963.1 - 0.061 13.5 0.0 11 6.2 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY93963.1 - 0.064 12.8 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.21 ORY93963.1 - 0.066 12.6 0.0 9.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 ORY93963.1 - 0.1 12.5 0.0 10 6.0 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Arf PF00025.21 ORY93963.1 - 0.15 11.5 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.25 ORY93963.1 - 0.15 11.7 0.0 17 4.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 ORY93963.1 - 0.24 11.1 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mito_carr PF00153.27 ORY93964.1 - 3e-55 184.1 0.0 6e-19 67.8 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TPX2 PF06886.11 ORY93967.1 - 4.4 7.6 7.2 6.8 7.0 0.8 2.3 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) AbiH PF14253.6 ORY93968.1 - 0.0081 16.1 0.1 0.0085 16.0 0.1 1.1 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH DSPc PF00782.20 ORY93969.1 - 1e-31 109.5 0.0 1.2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY93969.1 - 4.6e-05 23.1 0.0 5.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORY93969.1 - 0.007 16.1 0.0 0.0096 15.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 ORY93969.1 - 0.038 14.3 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain AA_permease_2 PF13520.6 ORY93970.1 - 8.7e-53 179.7 54.1 1.1e-52 179.4 54.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY93970.1 - 1e-17 63.9 48.1 1.5e-17 63.4 48.1 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 ORY93971.1 - 1.9e-75 253.7 0.0 2.4e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY93971.1 - 6.6e-36 123.9 0.0 1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY93971.1 - 8.5e-09 35.1 0.0 1e-06 28.3 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Rrn6 PF10214.9 ORY93971.1 - 0.0006 18.5 5.9 0.00083 18.0 5.9 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Kdo PF06293.14 ORY93971.1 - 0.0019 17.6 0.3 0.0037 16.6 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY93971.1 - 0.01 14.7 0.0 0.01 14.7 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase FliT PF05400.13 ORY93971.1 - 0.023 15.5 1.6 0.071 13.9 1.6 1.8 1 0 0 1 1 1 0 Flagellar protein FliT DNMT1-RFD PF12047.8 ORY93971.1 - 0.042 13.9 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Haspin_kinase PF12330.8 ORY93971.1 - 0.047 12.6 0.1 0.18 10.7 0.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY93971.1 - 0.15 12.0 2.3 0.38 10.6 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY93971.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.0 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Totivirus_coat PF05518.11 ORY93971.1 - 2.4 6.1 9.6 3.2 5.7 9.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein V-ATPase_G PF03179.15 ORY93972.1 - 8.4e-30 103.4 16.1 9.6e-30 103.2 16.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 ORY93972.1 - 0.03 14.4 11.9 0.03 14.4 11.9 2.1 1 1 0 2 2 2 0 ATP synthase B/B' CF(0) DUF2115 PF09888.9 ORY93972.1 - 0.047 14.2 5.1 0.058 13.9 5.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Strumpellin PF10266.9 ORY93972.1 - 0.1 10.3 5.1 0.11 10.2 5.1 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin AAA_15 PF13175.6 ORY93972.1 - 0.21 11.3 5.7 0.24 11.1 5.7 1.0 1 0 0 1 1 1 0 AAA ATPase domain SAM_Exu PF18609.1 ORY93972.1 - 0.21 11.7 0.3 0.21 11.7 0.3 2.4 1 1 0 2 2 2 0 Exuperantia SAM-like domain ATP11 PF06644.11 ORY93972.1 - 0.27 11.0 10.5 0.32 10.7 10.5 1.0 1 0 0 1 1 1 0 ATP11 protein Seryl_tRNA_N PF02403.22 ORY93972.1 - 0.36 11.1 11.6 0.89 9.8 11.6 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sds3 PF08598.11 ORY93972.1 - 0.52 10.3 9.4 0.17 11.9 4.6 1.9 1 1 1 2 2 2 0 Sds3-like AcylCoA_dehyd_C PF12186.8 ORY93972.1 - 0.62 10.2 7.4 0.29 11.3 2.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal GLTP PF08718.11 ORY93972.1 - 0.63 10.3 4.4 8 6.7 4.4 2.0 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) VGCC_beta4Aa_N PF12052.8 ORY93972.1 - 0.77 9.9 5.6 3.3 7.9 0.2 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal V-ATPase_G_2 PF16999.5 ORY93972.1 - 0.98 9.9 18.5 3.8 8.0 18.6 2.0 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit PEP-utilisers_N PF05524.13 ORY93972.1 - 1 9.6 9.3 2.8 8.1 9.3 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Muted PF14942.6 ORY93972.1 - 1.2 9.5 11.4 2.8 8.3 10.7 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4407 PF14362.6 ORY93972.1 - 2.6 7.3 11.5 3.3 7.0 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 ORY93972.1 - 8.5 5.2 6.3 9.9 4.9 6.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Choline_kinase PF01633.20 ORY93973.1 - 1.6e-56 191.3 0.1 8.8e-56 188.8 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORY93973.1 - 3.5e-09 37.0 0.0 5.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY93973.1 - 0.0022 17.3 0.1 1.3 8.2 0.1 2.3 2 0 0 2 2 2 2 Ecdysteroid kinase DnaJ PF00226.31 ORY93974.1 - 1.1e-17 63.8 1.3 1.1e-17 63.8 1.3 2.3 3 0 0 3 3 3 1 DnaJ domain RAC_head PF16717.5 ORY93974.1 - 1.1e-09 39.1 3.7 1.1e-09 39.1 3.7 3.6 4 0 0 4 4 4 1 Ribosome-associated complex head domain Hid1 PF12722.7 ORY93974.1 - 1.9 6.5 5.0 2.5 6.1 5.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 ORY93974.1 - 9.7 6.2 7.8 3.2 7.8 3.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Abhydrolase_1 PF00561.20 ORY93978.1 - 1.1e-25 90.8 0.0 2.5e-19 70.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY93978.1 - 1.2e-19 71.8 0.0 1.5e-19 71.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY93978.1 - 1e-13 51.1 0.0 1.7e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY93978.1 - 1.5e-08 34.6 0.0 5.6e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 ORY93978.1 - 5.9e-06 26.3 0.0 7.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ORY93978.1 - 2e-05 24.8 0.0 2.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 ORY93978.1 - 3.2e-05 23.5 0.0 4.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 ORY93978.1 - 0.00055 19.7 0.0 0.00072 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY93978.1 - 0.0013 18.2 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ORY93978.1 - 0.0037 16.2 0.0 0.0059 15.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme BAAT_C PF08840.11 ORY93978.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_8 PF06259.12 ORY93978.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF1749 PF08538.10 ORY93978.1 - 0.17 11.0 0.0 0.52 9.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.12 ORY93978.1 - 0.17 11.4 0.1 0.57 9.7 0.1 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) bZIP_2 PF07716.15 ORY93979.1 - 9e-08 32.1 9.7 9e-08 32.1 9.7 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY93979.1 - 1e-07 31.9 7.7 1e-07 31.9 7.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.8 ORY93979.1 - 4.5e-06 27.0 6.0 4.5e-06 27.0 6.0 3.7 5 0 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.17 ORY93979.1 - 0.0037 17.8 9.6 0.0037 17.8 9.6 2.3 1 1 1 2 2 2 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 ORY93979.1 - 0.4 10.0 3.8 0.59 9.5 3.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GIT_CC PF16559.5 ORY93979.1 - 1.1 9.1 6.0 2.3 8.2 6.0 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FapA PF03961.13 ORY93979.1 - 1.4 7.5 3.6 1.8 7.1 3.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TFIID_30kDa PF03540.13 ORY93980.1 - 3.6e-26 90.8 0.1 3.6e-26 90.8 0.1 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 ORY93980.1 - 0.16 12.0 0.1 0.81 9.7 0.1 2.0 1 1 0 1 1 1 0 Bromodomain associated DUF4106 PF13388.6 ORY93980.1 - 2.2 7.4 12.2 3.1 6.9 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF4112 PF13430.6 ORY93981.1 - 3.7e-33 113.9 0.5 4.9e-33 113.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CsbD PF05532.12 ORY93982.1 - 0.00026 20.8 0.7 0.5 10.3 0.4 2.7 2 1 0 2 2 2 2 CsbD-like Peptidase_M24 PF00557.24 ORY93983.1 - 1e-20 74.3 0.1 1.3e-20 74.0 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 ELFV_dehydrog PF00208.21 ORY93984.1 - 1.1e-56 192.3 0.0 2.1e-56 191.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ORY93984.1 - 3.5e-25 87.8 0.1 2.5e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ORY93984.1 - 0.015 15.2 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF234 PF03008.14 ORY93984.1 - 0.13 12.7 1.4 1.5 9.3 0.0 3.1 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function DUF792 PF05632.11 ORY93984.1 - 0.18 11.7 1.4 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF792) Nod1 PF17114.5 ORY93984.1 - 0.87 9.7 3.4 15 5.7 0.2 2.9 2 1 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 Ion_trans PF00520.31 ORY93985.1 - 8.2e-05 21.9 10.3 0.0001 21.6 10.3 1.1 1 0 0 1 1 1 1 Ion transport protein HCMV_UL139 PF12507.8 ORY93985.1 - 0.075 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein PKD_channel PF08016.12 ORY93985.1 - 0.078 11.6 6.8 0.12 11.0 6.4 1.5 1 1 0 1 1 1 0 Polycystin cation channel Rsm22 PF09243.10 ORY93986.1 - 9.9e-71 238.2 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 ORY93986.1 - 6e-06 26.9 0.0 1.4e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY93986.1 - 1.2e-05 25.3 0.0 3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY93986.1 - 2.4e-05 25.0 0.0 7.1e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY93986.1 - 0.00027 20.8 0.0 0.00064 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY93986.1 - 0.039 14.6 0.0 0.089 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HSP70 PF00012.20 ORY93987.1 - 8.3e-09 34.2 0.0 3.2e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORY93987.1 - 0.028 13.3 0.0 0.11 11.3 0.0 2.0 2 1 0 2 2 2 0 MreB/Mbl protein Ribosomal_L6 PF00347.23 ORY93988.1 - 7.8e-30 103.4 7.8 2.9e-18 66.3 3.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Pilin_GH PF16734.5 ORY93988.1 - 0.12 12.7 0.1 1.1 9.6 0.1 2.3 1 1 0 1 1 1 0 Type IV pilin-like G and H, putative Ank_5 PF13857.6 ORY93990.1 - 1.5e-18 66.6 0.3 3.6e-10 39.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY93990.1 - 5.4e-18 65.4 0.1 7.4e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY93990.1 - 3.9e-15 56.0 0.1 3.3e-07 30.7 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY93990.1 - 5.5e-14 50.9 0.1 0.00013 22.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY93990.1 - 3e-13 49.5 1.1 2.7e-05 24.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORY93991.1 - 4.6e-20 71.7 1.8 6.3e-12 45.8 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY93991.1 - 2.1e-16 59.8 0.4 1.8e-10 40.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY93991.1 - 2.2e-16 60.2 0.0 2.8e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY93991.1 - 1.7e-14 52.4 0.1 8.5e-06 25.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY93991.1 - 2.2e-14 53.2 1.4 8.8e-07 29.1 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF2384 PF09722.10 ORY93991.1 - 0.056 13.5 1.7 9 6.4 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2384) DUF1771 PF08590.10 ORY93992.1 - 2.4e-17 63.1 8.8 4.6e-17 62.1 8.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ORY93992.1 - 1.8e-09 37.8 0.1 4.8e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 ORY93992.1 - 3.9e-06 26.7 2.2 3.9e-06 26.7 2.2 3.5 3 0 0 3 3 3 1 Zinc finger domain CUE PF02845.16 ORY93992.1 - 6.4e-05 22.6 0.4 0.00012 21.7 0.4 1.5 1 0 0 1 1 1 1 CUE domain zf-CCCH PF00642.24 ORY93992.1 - 6.7e-05 22.7 8.5 0.001 18.9 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY93992.1 - 9.1e-05 22.2 9.6 0.00051 19.8 0.7 2.8 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY93992.1 - 0.02 15.4 11.6 0.93 10.1 3.6 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY93992.1 - 0.023 15.4 0.2 0.023 15.4 0.2 2.8 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 ORY93992.1 - 0.27 11.5 7.1 0.41 10.9 0.4 2.4 1 1 1 2 2 2 0 Zinc-finger containing family DUF1348 PF07080.11 ORY93994.1 - 2.6e-61 205.3 10.1 3e-61 205.1 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 ORY93994.1 - 3.8e-05 24.3 0.6 5.5e-05 23.8 0.6 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ORY93994.1 - 0.00062 20.1 0.0 0.00078 19.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 ORY93994.1 - 0.014 15.2 0.4 0.025 14.4 0.1 1.6 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase DUF2505 PF10698.9 ORY93994.1 - 0.071 13.2 0.2 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) DPBB_1 PF03330.18 ORY93995.1 - 2.9e-08 33.9 0.0 3.3e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 Lytic transglycolase zf-H2C2 PF09337.10 ORY93995.1 - 0.053 13.7 0.1 0.091 13.0 0.1 1.4 1 0 0 1 1 1 0 H2C2 zinc finger EBV-NA1 PF02905.14 ORY93995.1 - 0.097 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain DPBB_1 PF03330.18 ORY93996.1 - 8.9e-07 29.1 0.0 9.4e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Lytic transglycolase MTCP1 PF08991.10 ORY93997.1 - 7.7e-18 64.5 10.6 9.2e-18 64.2 10.6 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 ORY93997.1 - 0.00029 20.9 7.3 0.00073 19.6 7.3 1.8 1 1 0 1 1 1 1 CHCH domain DpnI_C PF17726.1 ORY93997.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Dam-replacing HTH domain PH PF00169.29 ORY93998.1 - 8.1e-21 74.5 0.8 1.9e-20 73.4 0.8 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 ORY93998.1 - 1.6e-13 50.3 0.1 3.3e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY93998.1 - 2.4e-12 46.2 0.1 7.1e-12 44.7 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 ORY93998.1 - 1.2e-11 44.5 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY93998.1 - 2e-11 44.2 0.1 3.7e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 ORY93998.1 - 6.7e-10 38.5 0.0 2.2e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain PH_11 PF15413.6 ORY93998.1 - 2.5e-09 37.5 4.9 3.9e-07 30.5 4.9 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain CH PF00307.31 ORY93998.1 - 3.6e-06 27.1 0.0 1.3e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain SAM_Ste50p PF09235.10 ORY93998.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_8 PF15409.6 ORY93998.1 - 0.0014 18.9 1.8 0.0059 16.9 1.8 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_PNT PF02198.16 ORY93998.1 - 0.0096 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PH_3 PF14593.6 ORY93998.1 - 0.048 13.8 0.6 0.12 12.5 0.3 1.8 2 0 0 2 2 2 0 PH domain Zn_clus PF00172.18 ORY93999.1 - 0.0003 20.8 9.9 0.0003 20.8 9.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORY93999.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold Acetyltransf_7 PF13508.7 ORY94000.1 - 2.1e-06 28.1 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY94000.1 - 3.9e-06 27.1 0.0 7.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY94000.1 - 9.1e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD PF00628.29 ORY94000.1 - 0.2 11.6 7.6 0.4 10.6 7.6 1.5 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 ORY94000.1 - 0.51 10.5 6.9 1.2 9.3 6.9 1.6 1 0 0 1 1 1 0 PHD-finger Acetyltransf_6 PF13480.7 ORY94001.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_S6 PF01250.17 ORY94002.1 - 1.1e-21 76.9 0.0 1.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 RTP1_C1 PF10363.9 ORY94003.1 - 2.5e-32 111.4 0.1 2.5e-32 111.4 0.1 2.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 ORY94003.1 - 0.0013 19.1 0.2 0.074 13.4 0.0 3.4 2 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 ORY94003.1 - 0.14 12.2 2.0 0.64 10.1 0.1 2.9 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 ORY94003.1 - 0.27 11.1 2.7 7.5 6.4 0.1 3.3 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PEP-utilisers_N PF05524.13 ORY94003.1 - 0.43 10.8 1.9 13 6.0 0.0 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Ribosomal_L3 PF00297.22 ORY94004.1 - 5e-186 618.0 11.1 5.7e-186 617.9 11.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Tho1_MOS11_C PF18592.1 ORY94004.1 - 0.059 13.2 0.2 0.42 10.5 0.0 2.5 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain UQ_con PF00179.26 ORY94005.1 - 1.4e-21 76.6 0.2 2.1e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RPEL PF02755.15 ORY94007.1 - 4.6e-18 64.3 8.8 4.7e-07 29.3 0.2 3.8 4 0 0 4 4 4 3 RPEL repeat DUF2737 PF10930.8 ORY94007.1 - 0.023 14.2 0.5 0.072 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) Thaumatin PF00314.17 ORY94009.1 - 3.9e-40 137.8 13.4 2.2e-38 132.0 13.4 2.2 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORY94009.1 - 0.00047 19.6 1.6 0.071 12.4 0.0 3.0 1 1 2 3 3 3 1 Beta-1,3-glucanase Cytomega_UL20A PF05984.12 ORY94009.1 - 0.99 9.7 5.5 2.4 8.5 5.5 1.7 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein DUF3336 PF11815.8 ORY94010.1 - 3e-33 114.4 0.0 2.1e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY94010.1 - 4.7e-23 82.4 0.0 8.8e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase FA_desaturase PF00487.24 ORY94011.1 - 9.8e-34 117.3 27.7 1.9e-33 116.4 27.7 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY94011.1 - 6.5e-13 48.6 0.1 1.4e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 ORY94012.1 - 2.3e-43 148.5 48.4 1.3e-33 116.4 21.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY94012.1 - 1.3e-11 44.1 10.2 1.3e-11 44.1 10.2 2.4 3 1 1 4 4 4 1 Sugar (and other) transporter Phage_holin_5_1 PF06946.11 ORY94012.1 - 0.3 11.5 0.0 0.3 11.5 0.0 2.9 3 1 1 4 4 4 0 Bacteriophage A118-like holin, Hol118 Lung_7-TM_R PF06814.13 ORY94013.1 - 3.2e-58 197.3 15.1 3.7e-58 197.1 15.1 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 ORY94013.1 - 0.00064 19.2 15.7 0.00064 19.2 15.7 1.7 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain V_ATPase_I PF01496.19 ORY94013.1 - 0.066 11.1 2.3 0.3 9.0 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF5501 PF17605.2 ORY94013.1 - 0.094 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5501) DUF3169 PF11368.8 ORY94013.1 - 0.93 8.9 12.3 0.079 12.5 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) zf-C2H2 PF00096.26 ORY94014.1 - 1.3e-07 31.7 12.7 0.00035 20.9 1.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY94014.1 - 3.5e-07 30.4 19.5 4.9e-06 26.7 0.2 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY94014.1 - 1.8e-06 28.3 12.5 0.0014 19.3 1.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY94014.1 - 0.001 19.3 0.3 0.001 19.3 0.3 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY94014.1 - 0.0014 18.6 3.9 0.045 13.8 0.9 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 ORY94014.1 - 0.0038 17.6 0.2 0.0038 17.6 0.2 2.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY94014.1 - 0.084 12.7 4.4 0.65 9.8 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 ORY94014.1 - 0.23 11.4 7.3 1.5 8.7 2.5 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain MFS_1_like PF12832.7 ORY94015.1 - 5.2e-58 196.7 5.8 7.4e-58 196.2 5.8 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 ORY94015.1 - 6e-18 64.9 34.4 8.6e-12 44.6 9.8 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 ORY94015.1 - 1e-08 34.6 21.1 6.4e-08 32.0 6.1 2.7 3 0 0 3 3 3 2 Nucleoside H+ symporter Abhydrolase_9_N PF15420.6 ORY94015.1 - 0.13 12.3 3.5 0.97 9.4 0.5 2.9 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus PNTB_4TM PF12769.7 ORY94015.1 - 0.18 12.3 2.5 0.74 10.3 0.1 2.9 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch LacY_symp PF01306.19 ORY94015.1 - 0.68 8.6 26.8 0.016 14.0 1.0 3.7 3 1 1 4 4 4 0 LacY proton/sugar symporter DUF4131 PF13567.6 ORY94015.1 - 0.84 9.3 9.3 5 6.7 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Gpr1_Fun34_YaaH PF01184.19 ORY94016.1 - 2.8e-36 125.1 21.2 3.3e-36 124.9 21.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Vir_act_alpha_C PF10400.9 ORY94017.1 - 0.043 14.5 0.1 0.45 11.2 0.0 2.6 2 0 0 2 2 2 0 Virulence activator alpha C-term NFRKB_winged PF14465.6 ORY94017.1 - 0.16 12.2 0.8 70 3.7 0.0 3.5 3 0 0 3 3 3 0 NFRKB Winged Helix-like TetR_C_28 PF17937.1 ORY94017.1 - 0.76 10.3 6.5 0.59 10.6 1.0 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Inhibitor_I78 PF11720.8 ORY94018.1 - 0.0009 19.3 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORY94018.1 - 0.077 13.7 0.0 0.13 13.0 0.0 1.3 1 0 0 1 1 1 0 Potato inhibitor I family Abhydrolase_3 PF07859.13 ORY94019.1 - 5.3e-29 101.6 0.0 8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY94019.1 - 5.4e-13 48.5 0.1 6.4e-12 45.0 0.1 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORY94019.1 - 0.00038 20.0 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family STIMATE PF12400.8 ORY94020.1 - 1.6e-31 109.5 7.1 2.2e-31 109.0 7.1 1.2 1 0 0 1 1 1 1 STIMATE family DHHC PF01529.20 ORY94020.1 - 0.019 15.0 0.2 0.019 15.0 0.2 2.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase Nop14 PF04147.12 ORY94023.1 - 0.22 9.7 17.6 0.26 9.4 17.6 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 ORY94023.1 - 0.43 9.9 22.2 0.52 9.6 22.2 1.1 1 0 0 1 1 1 0 BUD22 Raftlin PF15250.6 ORY94023.1 - 1.1 7.9 5.1 1.3 7.7 5.1 1.1 1 0 0 1 1 1 0 Raftlin PNISR PF15996.5 ORY94023.1 - 3.1 8.0 15.3 4 7.7 15.3 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PPP4R2 PF09184.11 ORY94023.1 - 5.6 6.5 16.3 8.1 5.9 16.1 1.4 1 1 0 1 1 1 0 PPP4R2 Na_Ca_ex PF01699.24 ORY94024.1 - 6.9e-17 61.8 47.6 2.4e-13 50.3 12.3 3.8 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 ORY94024.1 - 1.3e-13 51.4 27.8 1.5e-13 51.2 8.9 4.5 3 1 0 3 3 3 2 Inner membrane component domain Cwf_Cwc_15 PF04889.12 ORY94024.1 - 1.1 9.0 3.6 1.6 8.4 3.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Chitin_synth_2 PF03142.15 ORY94025.1 - 5.2e-239 794.2 0.7 7.3e-239 793.8 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY94025.1 - 4.8e-77 259.7 0.0 7.7e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY94025.1 - 5.1e-18 64.7 0.1 7.7e-17 61.0 0.2 2.7 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 ORY94025.1 - 1e-16 60.8 0.1 3.5e-09 36.7 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ORY94025.1 - 2.9e-15 56.7 3.1 2.9e-15 56.7 3.1 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY94025.1 - 3e-15 56.7 0.0 4.4e-14 52.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY94025.1 - 1.1e-05 25.4 0.0 0.0076 16.1 0.0 2.9 2 0 0 2 2 2 2 Glycosyl transferase family 2 G-alpha PF00503.20 ORY94025.1 - 0.002 17.4 0.6 0.009 15.2 0.3 2.0 2 0 0 2 2 2 1 G-protein alpha subunit Glyco_transf_21 PF13506.6 ORY94025.1 - 0.0022 17.5 0.0 0.04 13.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_29 PF13555.6 ORY94025.1 - 0.066 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY94025.1 - 0.3 11.5 6.0 0.34 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ORY94025.1 - 0.7 10.0 3.6 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4420 PF14390.6 ORY94026.1 - 0.026 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) RasGAP_C PF03836.15 ORY94027.1 - 0.011 15.9 1.5 0.012 15.7 1.5 1.2 1 0 0 1 1 1 0 RasGAP C-terminus COG2 PF06148.11 ORY94027.1 - 0.014 15.4 1.8 0.017 15.2 1.8 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 ORY94027.1 - 0.029 14.8 9.5 0.041 14.3 9.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF3552 PF12072.8 ORY94027.1 - 0.039 13.4 6.8 0.045 13.2 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HMMR_N PF15905.5 ORY94027.1 - 0.054 13.0 6.7 0.061 12.8 6.7 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cytochrom_C_2 PF01322.20 ORY94027.1 - 0.063 14.2 0.9 0.077 13.9 0.9 1.3 1 1 0 1 1 1 0 Cytochrome C' UPF0113_N PF17833.1 ORY94027.1 - 0.087 13.4 0.1 0.13 12.9 0.1 1.4 1 1 0 1 1 1 0 UPF0113 Pre-PUA domain Uso1_p115_C PF04871.13 ORY94027.1 - 0.13 12.6 8.6 0.16 12.3 8.6 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FAM76 PF16046.5 ORY94027.1 - 0.24 10.7 5.8 0.29 10.4 5.8 1.0 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 ORY94027.1 - 0.73 10.0 4.8 0.76 10.0 0.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mitofilin PF09731.9 ORY94027.1 - 0.86 8.4 8.5 1 8.1 8.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HALZ PF02183.18 ORY94027.1 - 1 9.6 7.4 1.7 8.9 2.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 ORY94027.1 - 1.8 9.3 5.7 2.5 8.8 5.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA XhlA PF10779.9 ORY94027.1 - 3 8.1 5.8 16 5.8 5.6 1.9 1 1 0 1 1 1 0 Haemolysin XhlA SlyX PF04102.12 ORY94027.1 - 3.2 8.4 8.3 25 5.6 7.5 2.3 1 1 0 1 1 1 0 SlyX Microtub_bd PF16796.5 ORY94028.1 - 0.00061 19.8 0.0 0.00077 19.4 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 ORY94028.1 - 0.0013 17.7 0.0 0.0015 17.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Dimeth_Pyl PF09505.10 ORY94028.1 - 0.02 13.4 0.0 0.02 13.4 0.0 1.0 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) RNB PF00773.19 ORY94029.1 - 1.1e-83 281.3 0.4 1.1e-83 281.3 0.4 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 ORY94029.1 - 3.7e-21 74.9 0.0 9.8e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORY94029.1 - 2.6e-14 53.3 0.0 2.6e-14 53.3 0.0 2.7 4 0 0 4 4 4 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 ORY94029.1 - 0.11 12.2 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain FAM104 PF15434.6 ORY94029.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.2 3 0 0 3 3 3 0 Family 104 zf_CCCH_4 PF18345.1 ORY94030.1 - 3.4e-07 30.1 2.4 5.5e-07 29.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORY94030.1 - 1.8e-06 27.7 1.1 3.2e-06 26.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY94030.1 - 1.3e-05 25.8 0.1 2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 ORY94030.1 - 1.8e-05 24.4 0.9 3e-05 23.7 0.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY94030.1 - 0.00026 21.3 0.7 0.00051 20.4 0.7 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Ribosomal_S3_C PF00189.20 ORY94031.1 - 2.1e-07 31.3 0.1 4.3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain VAR1 PF05316.12 ORY94031.1 - 4.1e-05 22.8 1.5 0.00015 20.9 0.0 2.2 2 1 1 3 3 3 1 Mitochondrial ribosomal protein (VAR1) N6_Mtase PF02384.16 ORY94032.1 - 2.2e-15 56.8 0.0 5.4e-14 52.2 0.0 2.4 2 1 0 2 2 2 1 N-6 DNA Methylase Eco57I PF07669.11 ORY94032.1 - 6e-06 26.7 0.0 1.9e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Eco57I restriction-modification methylase UPF0020 PF01170.18 ORY94032.1 - 0.00077 19.2 0.0 0.14 11.8 0.0 2.8 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 TaqI_C PF12950.7 ORY94032.1 - 0.0048 17.0 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain SPRY PF00622.28 ORY94033.1 - 4.7e-21 75.1 0.0 2e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 SPRY domain DUF2093 PF09866.9 ORY94033.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) POP1 PF06978.11 ORY94034.1 - 1.4e-33 116.6 17.8 9.2e-18 65.0 6.1 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 ORY94034.1 - 6.7e-28 96.9 0.0 1.9e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 ORY94034.1 - 0.0058 16.0 0.0 0.54 9.6 0.0 2.8 3 0 0 3 3 3 1 Aminomethyltransferase folate-binding domain E7 PF00527.18 ORY94035.1 - 0.85 9.9 6.6 0.2 11.9 1.9 2.3 2 0 0 2 2 2 0 E7 protein, Early protein Pkinase PF00069.25 ORY94036.1 - 3.8e-71 239.6 0.0 7.2e-71 238.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94036.1 - 7.8e-51 172.8 0.0 1.4e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY94036.1 - 7.6e-21 74.2 0.0 7.6e-21 74.2 0.0 2.6 3 0 0 3 3 3 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 ORY94036.1 - 1.4e-05 24.0 0.0 1.4e-05 24.0 0.0 2.9 3 1 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 ORY94036.1 - 5.1e-05 22.7 1.4 8.3e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY94036.1 - 0.0031 17.5 0.0 1.4 8.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Roughex PF06020.11 ORY94036.1 - 0.014 14.6 5.7 0.027 13.6 5.7 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Chitin_synth_1 PF01644.17 ORY94036.1 - 0.12 12.3 3.8 0.36 10.8 2.1 2.2 2 0 0 2 2 2 0 Chitin synthase DUF4078 PF13300.6 ORY94037.1 - 0.039 14.3 0.0 0.068 13.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4078) DDA1 PF10172.9 ORY94037.1 - 0.087 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase RhoGAP PF00620.27 ORY94038.1 - 7.2e-32 110.3 0.1 1.1e-31 109.7 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 ORY94038.1 - 9.7e-24 84.1 1.0 8.9e-23 81.0 0.4 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 ORY94038.1 - 0.00053 19.7 1.1 0.0058 16.4 0.1 2.7 2 1 0 3 3 3 1 CRAL/TRIO domain Peptidase_C12 PF01088.21 ORY94039.1 - 5e-52 176.7 0.1 6.3e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ORY94039.1 - 1.2e-05 25.1 0.2 1.2e-05 25.1 0.2 2.3 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolases CDC27 PF09507.10 ORY94039.1 - 0.059 12.8 1.6 5.6 6.2 0.4 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF4611 PF15387.6 ORY94039.1 - 3.8 7.8 7.8 0.29 11.4 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NDK PF00334.19 ORY94040.1 - 1.9e-52 176.8 0.0 2.2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TPT PF03151.16 ORY94041.1 - 6.4e-46 157.0 29.1 7.6e-46 156.8 29.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY94041.1 - 5.6e-13 48.8 29.1 7.6e-13 48.3 29.1 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY94041.1 - 6.8e-10 39.3 37.0 4.1e-06 27.0 14.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORY94041.1 - 0.00027 20.2 9.5 0.00077 18.7 1.5 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter p450 PF00067.22 ORY94042.1 - 4.9e-77 259.6 0.0 6e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY94043.1 - 2.5e-84 283.7 0.0 2.9e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 ORY94044.1 - 1.6e-53 181.8 0.0 4.4e-53 180.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94044.1 - 6.6e-34 117.4 0.0 9.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY94044.1 - 0.0011 18.4 0.2 0.0021 17.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY94044.1 - 0.0035 16.3 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FYVE PF01363.21 ORY94046.1 - 1.3e-17 63.7 7.6 1.3e-17 63.7 7.6 2.5 3 0 0 3 3 3 1 FYVE zinc finger Ank_4 PF13637.6 ORY94046.1 - 1.5e-09 38.2 0.2 1.4e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY94046.1 - 7.2e-09 35.7 0.1 1.9e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 ORY94046.1 - 2.4e-08 34.2 5.9 2.4e-08 34.2 5.9 4.0 3 1 0 3 3 3 1 Ring finger domain Ank_2 PF12796.7 ORY94046.1 - 8e-08 32.8 0.1 1.3e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY94046.1 - 5.8e-06 26.5 0.1 0.019 15.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat zf-RING_11 PF17123.5 ORY94046.1 - 2.9e-05 23.7 6.5 2.9e-05 23.7 6.5 2.5 3 0 0 3 3 3 1 RING-like zinc finger Ank_3 PF13606.6 ORY94046.1 - 3.2e-05 24.0 0.1 0.028 15.0 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat zf-C3HC4_2 PF13923.6 ORY94046.1 - 3.3e-05 23.6 4.6 3.3e-05 23.6 4.6 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Pex24p PF06398.11 ORY94046.1 - 0.00011 21.3 0.4 0.00015 20.8 0.4 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-RING_UBOX PF13445.6 ORY94046.1 - 0.02 14.9 6.1 0.02 14.9 6.1 3.8 3 1 0 3 3 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 ORY94046.1 - 0.24 11.7 16.5 0.04 14.2 8.7 3.2 2 2 0 2 2 2 0 RING-H2 zinc finger domain FANCL_C PF11793.8 ORY94046.1 - 0.28 11.4 8.0 0.38 11.0 3.8 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.7 ORY94046.1 - 2.3 8.3 10.0 3 7.9 0.2 3.1 2 1 0 2 2 2 0 Double zinc ribbon GLTP PF08718.11 ORY94047.1 - 1.9e-50 171.0 0.0 3e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DNTTIP1_dimer PF18192.1 ORY94047.1 - 0.0044 17.3 0.1 6.1 7.3 0.0 3.3 3 0 0 3 3 3 2 DNTTIP1 dimerisation domain DUF1024 PF06260.12 ORY94047.1 - 0.015 15.6 0.2 0.29 11.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) SNF2_N PF00176.23 ORY94049.1 - 1.3e-52 178.7 0.2 1.2e-43 149.2 0.1 2.5 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY94049.1 - 1e-12 48.4 0.0 3.1e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY94049.1 - 5.8e-08 32.9 0.1 1.1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 ORY94049.1 - 3.2e-05 23.7 10.8 3.2e-05 23.7 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY94049.1 - 9.6e-05 22.2 8.8 9.6e-05 22.2 8.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 ORY94049.1 - 0.00023 21.0 0.0 0.00062 19.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 ORY94049.1 - 0.0041 16.9 7.6 0.0041 16.9 7.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY94049.1 - 0.011 16.0 9.7 0.011 16.0 9.7 2.6 2 1 0 2 2 1 0 Ring finger domain Zn_Tnp_IS91 PF14319.6 ORY94049.1 - 0.097 12.7 13.5 0.45 10.6 3.2 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain AAA_22 PF13401.6 ORY94049.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-RING_UBOX PF13445.6 ORY94049.1 - 0.55 10.3 14.3 0.095 12.7 8.3 2.5 2 0 0 2 2 2 0 RING-type zinc-finger DMT_YdcZ PF04657.13 ORY94050.1 - 2.1e-10 41.0 8.0 2.9e-10 40.6 8.0 1.2 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ RNB PF00773.19 ORY94051.1 - 9.2e-106 353.8 0.0 2.2e-105 352.6 0.0 1.6 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 ORY94051.1 - 4.3e-18 65.4 0.0 1.1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 ORY94051.1 - 4.2e-17 61.9 0.0 9.7e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 ORY94051.1 - 2.2e-07 31.0 0.0 0.0039 17.3 0.0 3.1 3 0 0 3 3 3 2 Cold shock domain Rrp44_CSD1 PF17216.3 ORY94051.1 - 0.0002 21.1 0.0 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 1 Rrp44-like cold shock domain OB_RNB PF08206.11 ORY94051.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Rrp44_S1 PF17215.3 ORY94051.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 S1 domain FAM176 PF14851.6 ORY94051.1 - 0.19 11.4 6.9 3.5 7.3 0.5 2.4 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 ORY94051.1 - 0.55 10.3 7.9 1.3 9.0 0.6 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-O PF09496.10 ORY94052.1 - 1.4e-16 61.1 3.0 1.4e-16 61.1 3.0 2.4 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component Dynamin_M PF01031.20 ORY94052.1 - 0.032 13.5 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Dynamin central region HMMR_C PF15908.5 ORY94052.1 - 0.18 12.1 2.4 0.26 11.6 1.0 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DEK_C PF08766.11 ORY94053.1 - 0.00034 20.5 0.3 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_hydro_47 PF01532.20 ORY94054.1 - 1e-151 506.0 0.0 1.2e-151 505.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HAD_2 PF13419.6 ORY94055.1 - 1.7e-23 83.6 0.0 2.1e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY94055.1 - 2.1e-16 60.9 0.1 1.2e-14 55.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY94055.1 - 8.4e-10 38.6 0.1 1.8e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ORY94055.1 - 2.4e-07 31.4 0.0 6.3e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Stimulus_sens_1 PF13756.6 ORY94055.1 - 0.026 15.1 0.0 0.041 14.5 0.0 1.3 1 0 0 1 1 1 0 Stimulus-sensing domain Death PF00531.22 ORY94055.1 - 0.04 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Death domain Hydrolase_6 PF13344.6 ORY94055.1 - 0.052 13.7 0.0 0.31 11.2 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 ORY94055.1 - 0.052 13.5 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Acid_phosphat_B PF03767.14 ORY94055.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) WD40 PF00400.32 ORY94056.1 - 1e-07 32.5 0.6 0.0021 18.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY94056.1 - 2.2e-05 24.7 0.0 0.00067 19.9 0.0 3.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY94056.1 - 0.0016 17.0 0.1 0.0047 15.5 0.1 1.6 1 1 1 2 2 2 1 Cytochrome D1 heme domain Str_synth PF03088.16 ORY94056.1 - 0.0068 16.5 0.0 0.21 11.7 0.0 2.8 2 1 1 3 3 3 1 Strictosidine synthase DUF2415 PF10313.9 ORY94056.1 - 0.027 14.4 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Gmad1 PF10647.9 ORY94056.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.9 ORY94056.1 - 2.4 7.9 0.0 2.4 7.9 0.0 3.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature HEAT PF02985.22 ORY94057.1 - 1.7e-37 124.2 22.7 4.8e-05 23.3 0.0 12.9 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 ORY94057.1 - 7e-29 100.1 3.3 3.8e-05 24.0 0.2 7.9 2 1 7 9 9 9 8 HEAT repeats HEAT_EZ PF13513.6 ORY94057.1 - 5.7e-19 68.2 5.4 4.4e-07 30.3 0.0 7.1 6 1 1 7 7 7 5 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY94057.1 - 3e-08 34.1 0.2 3.6 8.2 0.0 6.5 3 3 5 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY94057.1 - 2.5e-06 27.6 6.5 1.7 8.7 0.3 5.6 3 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 ORY94057.1 - 7.9e-05 22.8 1.4 0.22 11.7 0.0 4.4 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 ORY94057.1 - 0.0012 17.5 2.4 0.57 8.7 0.4 3.9 1 1 2 4 4 4 3 Adaptin N terminal region HEAT_PBS PF03130.16 ORY94057.1 - 0.0026 18.3 0.1 5.9 7.9 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Apc15p PF05841.11 ORY94057.1 - 0.014 16.2 0.7 0.029 15.2 0.7 1.4 1 0 0 1 1 1 0 Apc15p protein CLASP_N PF12348.8 ORY94057.1 - 0.043 13.4 0.1 15 5.1 0.0 3.7 3 2 1 4 4 4 0 CLASP N terminal WD40 PF00400.32 ORY94058.1 - 1.1e-25 89.3 12.8 6.4e-06 26.8 0.5 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 ORY94058.1 - 2.9e-08 34.0 2.2 0.57 10.7 0.1 5.3 4 2 1 5 5 5 3 PQQ-like domain Nup160 PF11715.8 ORY94058.1 - 3.3e-05 22.7 4.9 0.12 10.9 0.2 4.0 2 2 3 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY94058.1 - 0.00036 20.8 0.1 1.2 9.5 0.1 3.4 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY94058.1 - 0.00048 19.0 0.0 0.0021 16.9 0.0 2.0 2 1 0 3 3 3 1 Nup133 N terminal like Tetraspanin PF00335.20 ORY94059.1 - 0.51 10.0 14.2 9.1 5.9 14.2 2.1 1 1 0 1 1 1 0 Tetraspanin family DEAD PF00270.29 ORY94060.1 - 7.6e-47 159.3 0.0 1.9e-46 158.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY94060.1 - 3.3e-32 111.1 0.0 9.9e-32 109.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RanBP PF00641.18 ORY94060.1 - 1.5e-18 65.8 15.9 1.2e-10 40.5 4.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others ResIII PF04851.15 ORY94060.1 - 0.00084 19.4 0.0 0.0027 17.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY94060.1 - 0.027 13.3 0.0 0.28 9.9 0.0 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DZR PF12773.7 ORY94060.1 - 0.027 14.5 10.0 0.15 12.1 10.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.20 ORY94060.1 - 0.34 10.7 2.9 9.4 6.1 0.6 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger TackOD1 PF18551.1 ORY94060.1 - 0.56 9.9 10.1 1.2 8.7 0.8 2.6 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 C1_2 PF03107.16 ORY94060.1 - 6.8 7.1 8.3 2 8.8 1.5 2.3 2 0 0 2 2 2 0 C1 domain Rubredoxin PF00301.20 ORY94060.1 - 8.2 6.5 9.8 5.2 7.2 0.3 3.3 3 0 0 3 3 3 0 Rubredoxin CXCR4_N PF12109.8 ORY94061.1 - 0.05 13.8 1.2 0.15 12.2 1.2 1.9 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal PTPlike_phytase PF14566.6 ORY94062.1 - 6.9e-138 455.1 0.4 7.7e-49 165.8 0.1 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 ORY94062.1 - 3e-07 30.3 0.0 0.018 14.8 0.0 3.6 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 ORY94062.1 - 0.001 19.1 0.0 0.19 11.6 0.0 3.2 3 0 0 3 3 3 1 Tyrosine phosphatase family SDF PF00375.18 ORY94063.1 - 3.1e-103 345.8 29.3 3.6e-103 345.6 29.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SpoIIE PF07228.12 ORY94064.1 - 1.9e-12 47.5 0.1 8.1e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ORY94064.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 ORY94064.1 - 2e-09 37.5 0.1 0.00066 19.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Transposase_24 PF03004.14 ORY94064.1 - 0.14 12.2 0.4 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) ABC2_membrane_2 PF12679.7 ORY94065.1 - 0.11 11.8 5.8 0.13 11.5 5.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.9 ORY94065.1 - 4 6.1 4.2 4.1 6.0 4.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RabGAP-TBC PF00566.18 ORY94066.1 - 3e-55 187.2 0.0 3e-55 187.2 0.0 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.9 ORY94066.1 - 0.0012 18.8 14.7 0.0012 18.8 14.7 2.0 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 ORY94066.1 - 0.012 15.5 2.6 0.012 15.5 2.6 3.4 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 ORY94066.1 - 0.019 15.0 12.7 0.019 15.0 0.4 3.6 2 1 1 3 3 3 0 bZIP transcription factor TPD52 PF04201.15 ORY94066.1 - 0.043 13.4 6.4 1.6 8.3 0.3 2.6 1 1 1 2 2 2 0 Tumour protein D52 family SOGA PF11365.8 ORY94066.1 - 0.051 14.7 2.7 0.051 14.7 2.7 3.1 4 0 0 4 4 2 0 Protein SOGA Cluap1 PF10234.9 ORY94066.1 - 0.067 12.6 12.8 0.13 11.6 12.8 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 TMPIT PF07851.13 ORY94066.1 - 0.071 12.3 6.6 0.13 11.5 6.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein KASH_CCD PF14662.6 ORY94066.1 - 0.073 12.9 17.1 0.048 13.5 13.9 2.3 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 ORY94066.1 - 0.14 12.5 8.8 0.19 12.0 2.9 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4279 PF14106.6 ORY94066.1 - 0.15 12.3 1.2 8.6 6.6 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) Spc7 PF08317.11 ORY94066.1 - 0.16 10.8 16.5 0.4 9.5 16.5 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein SHE3 PF17078.5 ORY94066.1 - 0.17 11.5 17.4 0.21 11.3 13.9 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Cnn_1N PF07989.11 ORY94066.1 - 0.27 11.4 14.0 0.3 11.3 5.0 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Phage_GP20 PF06810.11 ORY94066.1 - 0.28 11.0 10.2 0.15 11.8 5.6 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 BRE1 PF08647.11 ORY94066.1 - 0.43 10.7 15.0 2.8 8.1 1.1 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CdvA PF18822.1 ORY94066.1 - 0.52 10.2 15.4 2.1 8.2 7.3 3.3 3 1 1 4 4 2 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 ORY94066.1 - 0.62 10.1 7.2 2.1 8.4 3.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 ORY94066.1 - 0.72 10.2 18.7 0.049 14.0 5.9 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rx_N PF18052.1 ORY94066.1 - 0.77 10.1 8.3 0.1 12.8 2.0 2.6 2 1 1 3 3 2 0 Rx N-terminal domain Laminin_II PF06009.12 ORY94066.1 - 0.95 9.5 10.6 0.8 9.7 7.9 2.0 1 1 1 2 2 2 0 Laminin Domain II TSC22 PF01166.18 ORY94066.1 - 1.1 9.6 11.3 5.7 7.3 0.5 4.2 2 1 2 4 4 3 0 TSC-22/dip/bun family DUF4200 PF13863.6 ORY94066.1 - 1.1 9.6 20.8 0.55 10.7 12.2 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 ORY94066.1 - 1.1 8.4 21.8 0.67 9.2 7.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 ORY94066.1 - 1.2 9.5 14.8 0.051 13.9 4.8 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain Phlebovirus_NSM PF07246.11 ORY94066.1 - 1.3 8.4 5.9 2 7.7 5.9 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M dCache_2 PF08269.11 ORY94066.1 - 2.1 7.4 7.0 16 4.6 7.9 2.0 2 0 0 2 2 2 0 Cache domain Jnk-SapK_ap_N PF09744.9 ORY94066.1 - 2.3 8.4 30.4 0.67 10.2 15.2 2.8 2 1 1 3 3 2 0 JNK_SAPK-associated protein-1 GAS PF13851.6 ORY94066.1 - 2.5 7.4 27.2 0.015 14.7 11.8 3.3 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 ORY94066.1 - 2.5 7.4 14.9 4.5 6.5 14.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 ORY94066.1 - 2.6 8.1 10.5 4.1 7.5 0.8 2.7 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 ORY94066.1 - 2.8 8.5 27.3 0.22 12.1 12.9 2.9 2 1 1 3 3 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 ORY94066.1 - 3.5 8.1 7.7 40 4.7 2.3 3.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4349 PF14257.6 ORY94066.1 - 5.3 6.4 13.4 31 3.9 13.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DivIC PF04977.15 ORY94066.1 - 5.3 6.9 18.2 0.55 10.1 4.2 3.6 1 1 2 3 3 3 0 Septum formation initiator DASH_Duo1 PF08651.10 ORY94066.1 - 5.8 6.8 8.1 10 6.0 0.4 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 Exonuc_VII_L PF02601.15 ORY94066.1 - 6 6.3 12.9 1.2 8.7 9.6 1.5 2 0 0 2 2 1 0 Exonuclease VII, large subunit Cep57_CLD_2 PF14197.6 ORY94066.1 - 6.7 6.9 17.0 7.9 6.6 12.9 3.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Baculo_PEP_C PF04513.12 ORY94066.1 - 7.2 6.6 13.6 2.9 7.9 7.8 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 ORY94066.1 - 7.6 7.2 17.4 4.7 7.9 7.7 3.3 2 1 2 4 4 3 0 Initiation control protein YabA DUF724 PF05266.14 ORY94066.1 - 8.6 6.1 12.1 2.1 8.1 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fungal_trans PF04082.18 ORY94067.1 - 0.002 17.2 1.4 0.0084 15.2 1.4 2.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_2 PF13646.6 ORY94068.1 - 1e-13 51.4 2.4 4.6e-07 30.1 0.0 4.4 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 ORY94068.1 - 1.2e-13 50.0 0.4 0.026 14.8 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 ORY94068.1 - 1.8e-07 31.3 3.5 0.00012 22.1 0.0 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY94068.1 - 8.1e-07 28.0 0.2 0.0014 17.3 0.0 2.6 1 1 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.8 ORY94068.1 - 0.00012 21.7 0.8 0.014 15.0 0.0 3.5 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 ORY94068.1 - 0.0021 18.5 1.4 3 8.5 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Cnd3 PF12719.7 ORY94068.1 - 0.0054 16.0 0.5 0.065 12.4 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain API5 PF05918.11 ORY94068.1 - 0.026 13.4 0.1 0.29 9.9 0.0 2.4 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) PRA1 PF03208.19 ORY94068.1 - 0.044 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 PRA1 family protein Vac14_Fab1_bd PF12755.7 ORY94068.1 - 0.05 14.2 8.1 23 5.7 0.0 5.5 3 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region TFIIA PF03153.13 ORY94069.1 - 0.047 13.7 29.9 0.053 13.5 29.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LpxK PF02606.14 ORY94069.1 - 0.27 10.3 3.9 0.33 10.0 3.9 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase SR-25 PF10500.9 ORY94069.1 - 0.28 10.7 30.3 0.28 10.7 18.0 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.14 ORY94069.1 - 0.31 11.0 17.6 0.36 10.8 17.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 ORY94069.1 - 2.4 8.1 12.1 3.2 7.7 12.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 ORY94069.1 - 4.8 6.9 11.7 6.3 6.5 11.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Proteasome PF00227.26 ORY94071.1 - 1.5e-27 96.3 0.0 1.9e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 ORY94074.1 - 1.1e-55 188.8 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94074.1 - 5.9e-41 140.5 0.0 8.8e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY94074.1 - 1.6e-08 33.7 0.6 1.5e-06 27.3 0.5 2.9 2 1 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 ORY94074.1 - 0.0032 16.9 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ribosomal_S19e PF01090.19 ORY94075.1 - 2.2e-59 199.1 0.1 2.4e-59 198.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Zn_clus PF00172.18 ORY94076.1 - 5e-05 23.3 10.5 5e-05 23.3 10.5 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_3 PF01764.25 ORY94077.1 - 7.6e-09 35.6 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORY94077.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY94077.1 - 0.03 14.9 0.5 0.062 13.9 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY94077.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BAR_2 PF10455.9 ORY94079.1 - 6.8e-57 192.8 5.0 9.6e-57 192.3 5.0 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORY94079.1 - 1.3e-20 74.1 10.5 8.3e-20 71.5 10.5 1.9 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORY94079.1 - 3.5e-05 23.6 7.5 0.00071 19.4 6.0 3.1 1 1 1 2 2 2 1 BAR domain of APPL family SUIM_assoc PF16619.5 ORY94079.1 - 0.0015 18.5 3.7 0.0015 18.5 3.7 1.8 2 0 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 MRG PF05712.13 ORY94079.1 - 0.1 11.9 2.5 0.17 11.2 2.1 1.6 1 1 0 1 1 1 0 MRG Serine_rich PF08824.10 ORY94079.1 - 0.28 11.2 6.2 0.13 12.2 1.5 2.3 2 1 0 2 2 2 0 Serine rich protein interaction domain Vps5 PF09325.10 ORY94079.1 - 0.65 9.5 7.7 8 5.9 0.0 3.2 2 1 0 2 2 2 0 Vps5 C terminal like PKI PF02827.16 ORY94079.1 - 0.68 10.2 3.7 7.3 6.9 2.1 2.6 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Syntaxin_2 PF14523.6 ORY94079.1 - 0.7 10.3 10.3 0.9 9.9 7.0 2.7 1 1 1 2 2 1 0 Syntaxin-like protein TFIIA PF03153.13 ORY94079.1 - 1.1 9.2 15.6 1.3 9.0 15.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Draxin PF15550.6 ORY94079.1 - 1.1 9.0 6.6 1.6 8.5 6.6 1.2 1 0 0 1 1 1 0 Draxin zf-RING_2 PF13639.6 ORY94080.1 - 8.3e-10 38.8 4.7 2e-09 37.6 4.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY94080.1 - 1.4e-08 34.9 2.7 3.1e-08 33.8 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY94080.1 - 3.2e-07 30.1 2.5 3.2e-07 30.1 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY94080.1 - 7.7e-07 29.0 1.3 1.4e-06 28.1 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY94080.1 - 1.9e-06 27.6 3.0 3.5e-06 26.8 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY94080.1 - 0.00036 20.5 3.4 0.00095 19.1 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY94080.1 - 0.00047 20.0 2.6 0.0009 19.1 2.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORY94080.1 - 0.00048 20.1 1.5 0.0014 18.6 1.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY94080.1 - 0.0012 18.4 4.0 0.013 15.1 4.0 2.2 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORY94080.1 - 0.004 16.9 8.7 0.0059 16.3 0.2 2.8 3 0 0 3 3 2 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 ORY94080.1 - 0.0047 16.8 6.9 0.025 14.4 6.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 ORY94080.1 - 0.59 10.3 4.7 1.4 9.1 4.7 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 ORY94080.1 - 5.3 7.3 6.5 27 5.1 6.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Fungal_trans PF04082.18 ORY94081.1 - 7.6e-32 110.4 0.6 7.6e-32 110.4 0.6 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 ORY94081.1 - 0.0062 15.4 5.2 0.13 11.1 5.3 2.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY94082.1 - 8.3e-12 45.0 11.8 1.1e-11 44.6 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tup_N PF08581.10 ORY94083.1 - 0.012 16.0 5.6 0.012 16.0 5.6 9.6 4 3 5 9 9 9 0 Tup N-terminal Apolipoprotein PF01442.18 ORY94083.1 - 0.014 15.2 14.0 0.014 15.2 14.0 5.8 1 1 4 5 5 5 0 Apolipoprotein A1/A4/E domain Pkinase PF00069.25 ORY94085.1 - 5.5e-52 176.7 0.0 9.6e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94085.1 - 1.4e-29 103.2 0.0 2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY94085.1 - 0.0009 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY94085.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ORY94085.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 ORY94085.1 - 0.23 11.4 1.2 0.59 10.0 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family HLH PF00010.26 ORY94086.1 - 4e-07 29.9 2.6 9e-07 28.8 2.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain T2SSF PF00482.23 ORY94086.1 - 0.73 9.8 2.5 20 5.2 0.0 2.8 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F HTH_32 PF13565.6 ORY94087.1 - 0.00098 19.7 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Terminase_5 PF06056.12 ORY94087.1 - 0.0025 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) Sigma70_r4_2 PF08281.12 ORY94087.1 - 0.037 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 ORY94087.1 - 0.063 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 ORY94087.1 - 0.064 13.6 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.6 ORY94087.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF4914 PF16260.5 ORY94087.1 - 0.093 10.8 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) DUF4218 PF13960.6 ORY94091.1 - 0.00022 20.8 0.1 0.00097 18.7 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 ORY94091.1 - 0.00054 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 HTH_32 PF13565.6 ORY94092.1 - 3.4e-07 30.8 0.0 9.9e-07 29.3 0.0 1.8 2 0 0 2 2 1 1 Homeodomain-like domain HTH_28 PF13518.6 ORY94092.1 - 7.7e-05 22.7 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ORY94092.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 ORY94092.1 - 0.0018 18.4 0.0 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 ORY94092.1 - 0.0018 18.5 0.0 0.004 17.4 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_Tnp_1_2 PF13022.6 ORY94092.1 - 0.0051 17.0 0.1 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase DUF1804 PF08822.11 ORY94092.1 - 0.0098 15.9 0.0 0.015 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1804) DDE_3 PF13358.6 ORY94092.1 - 0.011 15.4 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 0 DDE superfamily endonuclease Terminase_5 PF06056.12 ORY94092.1 - 0.013 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) UPF0175 PF03683.13 ORY94092.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_Tnp_1 PF01527.20 ORY94092.1 - 0.033 14.5 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 ORY94092.1 - 0.061 13.4 0.1 0.17 11.9 0.1 1.8 1 1 0 1 1 1 0 Winged helix-turn helix APP_E2 PF12925.7 ORY94092.1 - 0.061 13.0 0.9 0.085 12.6 0.1 1.7 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein HTH_IclR PF09339.10 ORY94092.1 - 0.085 12.7 0.0 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain TrmB PF01978.19 ORY94092.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_3 PF01381.22 ORY94092.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Phage_integrase PF00589.22 ORY94094.1 - 0.00055 19.8 0.0 0.012 15.4 0.0 2.0 1 1 1 2 2 2 1 Phage integrase family Omptin PF01278.20 ORY94094.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Omptin family PDEase_I_N PF08499.12 ORY94094.1 - 0.047 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DLP_helical PF18709.1 ORY94095.1 - 0.041 13.1 4.8 0.58 9.3 0.7 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain Hydrolase_4 PF12146.8 ORY94100.1 - 1.2e-07 31.3 0.2 2.9e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY94100.1 - 0.00051 19.6 0.3 0.0026 17.3 0.3 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORY94100.1 - 0.0022 17.6 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ORY94100.1 - 0.007 16.2 0.0 0.088 12.6 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ORY94100.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3245 PF11595.8 ORY94102.1 - 8.9e-07 29.5 22.7 9.4e-06 26.2 21.2 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) DUF3526 PF12040.8 ORY94102.1 - 0.0019 18.7 0.5 0.0019 18.7 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3526) G-patch_2 PF12656.7 ORY94102.1 - 0.1 12.7 0.0 0.1 12.7 0.0 3.0 3 1 0 3 3 3 0 G-patch domain NOP19 PF10863.8 ORY94102.1 - 0.11 12.4 15.9 0.12 12.2 0.4 2.8 2 1 1 3 3 3 0 Nucleolar protein 19 DUF2052 PF09747.9 ORY94102.1 - 0.56 10.3 20.0 0.058 13.5 13.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SID-1_RNA_chan PF13965.6 ORY94102.1 - 2 6.7 5.4 2.1 6.7 5.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ANAPC15 PF15243.6 ORY94102.1 - 2.4 8.6 19.9 0.072 13.5 7.7 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 Ribosomal_L2_C PF03947.18 ORY94103.1 - 1.5e-44 151.2 3.7 2.4e-44 150.6 3.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY94103.1 - 4.5e-15 55.4 0.1 1e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DNA_ligase_A_M PF01068.21 ORY94104.1 - 1.2e-51 175.2 0.0 2e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY94104.1 - 4.5e-34 118.3 0.0 7.4e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY94104.1 - 6.2e-20 71.7 0.3 1.6e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Trypan_PARP PF05887.11 ORY94104.1 - 2 8.4 9.5 3.6 7.6 9.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Calcipressin PF04847.12 ORY94105.1 - 4.4e-33 114.6 0.3 7.8e-33 113.8 0.3 1.4 1 1 0 1 1 1 1 Calcipressin zf-RanBP PF00641.18 ORY94107.1 - 7.6e-26 89.1 36.5 4.6e-08 32.2 3.9 4.3 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others RNase_T PF00929.24 ORY94107.1 - 2.7e-10 41.0 0.1 5.9e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 ORY94107.1 - 2.2e-07 30.6 0.0 5.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.13 ORY94107.1 - 0.44 8.8 6.4 0.58 8.5 6.4 1.1 1 0 0 1 1 1 0 Menin Rubredoxin PF00301.20 ORY94107.1 - 1.5 8.9 14.1 20 5.3 0.5 4.9 4 0 0 4 4 4 0 Rubredoxin DZR PF12773.7 ORY94107.1 - 3.3 7.8 27.7 4.4 7.4 1.9 4.1 2 1 1 3 3 3 0 Double zinc ribbon Yippee-Mis18 PF03226.14 ORY94108.1 - 1.1e-11 44.9 0.2 1.2e-11 44.8 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 ORY94108.1 - 0.0047 16.7 0.1 0.0061 16.4 0.1 1.2 1 0 0 1 1 1 1 HNH endonuclease DUF2039 PF10217.9 ORY94108.1 - 0.013 15.8 0.7 0.015 15.6 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Rho_N PF07498.12 ORY94109.1 - 0.038 13.9 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain SWIRM-assoc_2 PF16496.5 ORY94109.1 - 0.099 11.5 10.7 0.13 11.1 10.7 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Macoilin PF09726.9 ORY94109.1 - 0.13 10.8 8.3 0.15 10.6 8.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF755 PF05501.11 ORY94109.1 - 4.9 7.4 25.2 6.8 7.0 9.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DRY_EERY PF09750.9 ORY94110.1 - 2.7e-23 82.7 0.5 3.6e-23 82.3 0.0 1.4 2 0 0 2 2 2 1 Alternative splicing regulator EamA PF00892.20 ORY94111.1 - 1.3e-10 41.6 34.7 3.6e-05 24.0 8.7 3.0 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 ORY94111.1 - 0.0023 17.5 13.2 0.0042 16.6 13.2 1.4 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 ORY94111.1 - 0.097 11.9 22.1 0.64 9.2 20.5 2.3 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 ORY94111.1 - 0.21 10.7 10.0 0.45 9.6 10.0 1.6 1 1 0 1 1 1 0 Nucleotide-sugar transporter DUF5516 PF17637.2 ORY94111.1 - 0.91 9.3 6.1 1.2 8.9 0.6 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5516) DUF4179 PF13786.6 ORY94111.1 - 0.95 10.0 7.6 9.7 6.7 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF4260 PF14079.6 ORY94111.1 - 4.9 7.1 11.0 0.11 12.4 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) PIRT PF15099.6 ORY94111.1 - 5.7 6.5 6.1 3.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Pmp3 PF01679.17 ORY94112.1 - 1.1e-19 70.4 12.7 1.1e-19 70.4 12.7 1.8 2 0 0 2 2 2 1 Proteolipid membrane potential modulator DUF4191 PF13829.6 ORY94112.1 - 0.036 13.4 0.1 0.044 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3165 PF11364.8 ORY94112.1 - 0.041 14.2 1.3 0.059 13.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) MSA-2c PF12238.8 ORY94112.1 - 0.064 13.2 3.2 0.083 12.9 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c TctA PF01970.16 ORY94112.1 - 0.099 11.3 2.9 0.13 11.0 2.9 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DHHC PF01529.20 ORY94113.1 - 6.9e-37 126.5 7.2 6.9e-37 126.5 7.2 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase IFT43 PF15305.6 ORY94113.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Zip PF02535.22 ORY94114.1 - 9.6e-66 222.3 8.7 1.5e-65 221.6 8.7 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter ORC6 PF05460.13 ORY94114.1 - 0.015 14.6 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Phage_holin_Dp1 PF16938.5 ORY94114.1 - 0.041 14.1 0.5 0.091 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative phage holin Dp-1 CDC45 PF02724.14 ORY94114.1 - 0.069 11.4 2.3 0.089 11.1 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 ORY94114.1 - 2.1 8.1 3.7 3.1 7.5 3.7 1.2 1 0 0 1 1 1 0 Connexin Ribosomal_S24e PF01282.19 ORY94115.1 - 1.7e-37 127.2 0.6 2e-37 127.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S24e Kelch_2 PF07646.15 ORY94117.1 - 1.3e-18 66.1 3.0 1.7e-05 24.6 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 ORY94117.1 - 3.3e-17 62.1 0.3 3.2e-05 23.8 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 ORY94117.1 - 5.1e-16 58.3 0.6 0.00038 20.6 0.1 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 ORY94117.1 - 1.8e-13 49.8 0.8 0.0014 18.2 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 ORY94117.1 - 5e-13 48.8 3.4 0.00018 21.4 0.0 4.7 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY94117.1 - 2.9e-11 43.4 9.8 2.8e-07 30.7 0.0 6.2 6 1 0 6 6 6 2 Galactose oxidase, central domain BTB PF00651.31 ORY94117.1 - 2.4e-10 40.6 0.1 0.00033 20.8 0.3 2.4 2 0 0 2 2 2 2 BTB/POZ domain AA_permease_2 PF13520.6 ORY94118.1 - 8.8e-60 202.7 38.3 1.1e-59 202.4 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY94118.1 - 1.3e-21 76.7 37.6 4.4e-21 75.0 37.6 1.6 1 1 0 1 1 1 1 Amino acid permease OST3_OST6 PF04756.13 ORY94118.1 - 2.5 7.4 6.4 0.49 9.7 0.9 2.5 2 1 1 3 3 3 0 OST3 / OST6 family, transporter family PalH PF08733.10 ORY94118.1 - 3.6 6.5 11.0 0.076 12.0 4.2 1.6 2 0 0 2 2 2 0 PalH/RIM21 DSPc PF00782.20 ORY94119.1 - 1.2e-06 28.3 0.0 1.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY94119.1 - 3.5e-05 23.5 0.0 4.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORY94119.1 - 0.0018 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pkinase PF00069.25 ORY94120.1 - 1.4e-66 224.6 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94120.1 - 5.9e-19 68.4 0.0 8.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY94120.1 - 1e-07 32.1 0.1 3.9e-06 27.0 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY94120.1 - 0.017 14.5 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY94120.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 ORY94120.1 - 0.022 14.3 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase LEH PF07858.12 ORY94120.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Cyt-b5 PF00173.28 ORY94121.1 - 6.5e-23 80.7 0.2 8e-23 80.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MAP65_ASE1 PF03999.12 ORY94122.1 - 8.8e-77 259.2 33.6 1.2e-76 258.8 33.6 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Methyltransf_11 PF08241.12 ORY94125.1 - 2.5e-15 56.9 0.0 1.2e-14 54.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY94125.1 - 6.9e-12 45.9 0.0 3.6e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY94125.1 - 1.6e-10 41.1 0.0 2.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY94125.1 - 9.8e-06 25.4 0.0 2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY94125.1 - 3.3e-05 24.6 0.0 0.00017 22.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY94125.1 - 0.00067 19.1 0.1 0.0023 17.3 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 ORY94125.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 ORY94125.1 - 0.0049 15.5 0.0 0.0063 15.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 ORY94125.1 - 0.032 13.1 0.0 0.1 11.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) HSP70 PF00012.20 ORY94126.1 - 2.2e-236 785.8 11.8 2.5e-236 785.6 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY94126.1 - 6.6e-18 64.6 2.6 5e-17 61.7 1.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORY94126.1 - 0.0023 17.7 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 ORY94126.1 - 0.0049 15.9 0.3 0.19 10.6 0.1 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain DUF3552 PF12072.8 ORY94126.1 - 0.0073 15.7 1.5 0.0073 15.7 1.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Raco_middle PF17651.1 ORY94126.1 - 0.028 14.1 0.3 4.4 7.0 0.0 3.4 2 1 1 3 3 3 0 RACo middle region Asp_decarbox PF02261.16 ORY94126.1 - 0.03 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Aspartate decarboxylase Hydantoinase_A PF01968.18 ORY94126.1 - 0.03 13.6 0.3 0.094 12.0 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORY94126.1 - 0.065 12.7 1.4 9.1 5.7 0.1 2.7 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family eIF3_N PF09440.10 ORY94126.1 - 0.1 13.0 5.8 0.041 14.3 1.3 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Cnn_1N PF07989.11 ORY94127.1 - 0.0023 18.1 2.0 0.0046 17.1 2.0 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 HMG_box_5 PF14887.6 ORY94127.1 - 0.0061 16.5 1.1 0.023 14.7 0.1 2.2 2 1 1 3 3 3 1 HMG (high mobility group) box 5 Speriolin_N PF15058.6 ORY94127.1 - 0.021 14.9 1.8 0.021 14.9 1.8 2.2 2 0 0 2 2 2 0 Speriolin N terminus ADIP PF11559.8 ORY94127.1 - 1.3 9.1 10.5 0.073 13.2 4.7 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NDK PF00334.19 ORY94128.1 - 2.7e-51 173.1 0.0 4e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_C65 PF10275.9 ORY94129.1 - 3.9e-66 223.0 0.1 4.6e-66 222.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 ORY94129.1 - 3.6e-05 24.3 0.1 0.0045 17.5 0.1 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease Vps52 PF04129.12 ORY94130.1 - 4.4e-137 457.9 11.8 5.7e-137 457.5 11.8 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 ORY94130.1 - 2e-07 29.8 6.2 1.4e-05 23.8 1.1 2.4 2 1 0 2 2 2 2 Exocyst complex component Sec3 COG2 PF06148.11 ORY94130.1 - 1.3e-05 25.3 4.4 2.3e-05 24.5 2.5 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 UPF0449 PF15136.6 ORY94130.1 - 0.088 13.3 0.8 0.34 11.4 0.8 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 CHDCT2 PF08074.11 ORY94130.1 - 0.12 12.6 3.6 1.9 8.6 0.4 3.5 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain Cep57_MT_bd PF06657.13 ORY94130.1 - 1 9.8 3.7 2.1 8.9 0.2 2.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 AMP-binding PF00501.28 ORY94131.1 - 1.7e-37 129.0 0.0 3.1e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORY94131.1 - 2.6e-32 112.0 0.0 2.2e-31 109.0 0.0 2.5 3 0 0 3 3 3 1 Male sterility protein PP-binding PF00550.25 ORY94131.1 - 7.4e-13 48.7 0.2 1.4e-12 47.8 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORY94131.1 - 2.1e-09 37.2 0.0 8.7e-09 35.2 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sgf11 PF08209.11 ORY94132.1 - 6.9e-14 51.1 0.4 6.9e-14 51.1 0.4 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DZR PF12773.7 ORY94132.1 - 0.044 13.8 1.4 0.08 13.0 1.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Tho2 PF11262.8 ORY94132.1 - 0.076 12.2 0.4 0.1 11.8 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 F-box PF00646.33 ORY94134.1 - 1.9e-07 30.8 0.3 5e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY94134.1 - 3.4e-05 23.7 0.3 3.4e-05 23.7 0.3 2.0 2 1 0 2 2 2 1 F-box-like Metallophos PF00149.28 ORY94136.1 - 1.1e-11 45.6 0.0 1.6e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY94136.1 - 5.5e-07 29.9 0.0 1.1e-06 28.9 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF1100 PF06500.11 ORY94136.1 - 0.043 12.6 0.1 0.066 12.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF2207 PF09972.9 ORY94136.1 - 0.05 12.4 0.1 0.072 11.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 ORY94136.1 - 0.066 14.1 0.1 0.15 13.0 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain COX6C PF02937.15 ORY94136.1 - 0.096 12.8 0.4 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Pilin_N PF07790.11 ORY94136.1 - 0.11 13.4 0.8 0.27 12.2 0.5 1.8 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Peptidase_S13 PF02113.15 ORY94136.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family CotH PF08757.11 ORY94137.1 - 8.4e-33 114.3 1.5 1.2e-32 113.8 1.5 1.2 1 0 0 1 1 1 1 CotH kinase protein Peptidase_C54 PF03416.19 ORY94138.1 - 5.9e-103 344.1 0.0 7e-103 343.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 IGPD PF00475.18 ORY94139.1 - 2.8e-62 209.3 0.3 3.9e-62 208.8 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase RPN7 PF10602.9 ORY94140.1 - 6e-39 133.5 1.8 1.5e-38 132.3 1.8 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORY94140.1 - 7.5e-17 61.8 6.0 9e-17 61.5 0.7 2.9 2 1 0 2 2 2 1 PCI domain MAS20 PF02064.15 ORY94140.1 - 0.00047 20.3 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 MAS20 protein import receptor Flg_hook PF02120.16 ORY94140.1 - 0.046 13.6 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 Flagellar hook-length control protein FliK Spt20 PF12090.8 ORY94141.1 - 1.6e-29 103.1 0.4 3.7e-19 69.3 0.2 12.0 5 3 4 9 9 9 2 Spt20 family MFS_1 PF07690.16 ORY94142.1 - 3.2e-24 85.5 29.2 1.8e-23 83.0 28.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 ORY94143.1 - 1.6e-15 57.2 12.9 0.032 15.1 0.0 7.0 7 0 0 7 7 6 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 ORY94143.1 - 5.5e-10 38.9 12.2 5.5e-10 38.9 12.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY94143.1 - 1.3e-09 37.8 8.4 1.3e-09 37.8 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY94143.1 - 7.4e-09 35.5 10.0 8.2e-09 35.3 7.2 2.4 1 1 1 2 2 2 1 RING-type zinc-finger WD40_like PF17005.5 ORY94143.1 - 2.1e-08 33.9 0.2 9.7e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain zf-RING_5 PF14634.6 ORY94143.1 - 2.6e-08 33.7 11.5 2.6e-08 33.7 11.5 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY94143.1 - 5.4e-07 29.8 12.2 5.4e-07 29.8 12.2 1.9 2 0 0 2 2 1 1 Ring finger domain ANAPC4_WD40 PF12894.7 ORY94143.1 - 7e-07 29.5 0.1 0.62 10.4 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_4 PF14447.6 ORY94143.1 - 8.6e-07 28.7 12.4 2e-06 27.5 9.3 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY94143.1 - 9.3e-07 28.9 7.9 9.3e-07 28.9 7.9 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY94143.1 - 1.8e-06 27.7 12.8 1.8e-06 27.7 12.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 ORY94143.1 - 3e-06 27.3 0.6 1.8e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.7 ORY94143.1 - 0.0016 18.7 10.8 0.0062 16.8 10.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 ORY94143.1 - 0.0028 17.3 7.2 0.0028 17.3 7.2 2.6 2 1 0 2 2 2 1 P-11 zinc finger zf-RING_10 PF16685.5 ORY94143.1 - 0.032 14.4 5.7 0.034 14.3 3.0 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-Di19 PF05605.12 ORY94143.1 - 0.034 14.4 7.4 1.6 9.1 1.6 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF87 PF01935.17 ORY94143.1 - 0.041 14.0 5.0 1.7 8.7 3.5 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain zf-RING_4 PF14570.6 ORY94143.1 - 0.25 11.1 11.8 0.16 11.8 7.9 2.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF2701 PF10857.8 ORY94143.1 - 0.28 11.2 1.6 0.76 9.8 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) zf-RING_6 PF14835.6 ORY94143.1 - 0.33 10.9 4.5 0.82 9.6 4.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn-C2H2_12 PF18112.1 ORY94143.1 - 1.2 9.7 11.4 2.3 8.8 0.1 4.3 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Spt20 PF12090.8 ORY94143.1 - 1.2 8.7 27.2 1.1 8.9 11.7 2.9 3 0 0 3 3 3 0 Spt20 family Vps39_2 PF10367.9 ORY94143.1 - 2.4 8.7 17.0 15 6.1 2.2 4.6 3 2 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zinc-ribbons_6 PF07191.12 ORY94143.1 - 3.3 7.8 12.6 1.1 9.3 6.7 2.7 2 1 0 2 2 2 0 zinc-ribbons zf-Nse PF11789.8 ORY94143.1 - 3.5 7.5 10.9 0.5 10.2 6.7 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4744 PF15918.5 ORY94144.1 - 0.0055 17.5 2.6 0.66 10.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4744) GET2 PF08690.10 ORY94144.1 - 0.32 10.6 14.7 0.46 10.1 14.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 SUIM_assoc PF16619.5 ORY94144.1 - 0.71 10.0 24.8 0.13 12.3 12.0 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 STE2 PF02116.15 ORY94145.1 - 0.029 13.7 0.2 0.034 13.5 0.2 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR Thi4 PF01946.17 ORY94146.1 - 1.9e-109 364.4 0.7 2.3e-109 364.2 0.7 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY94146.1 - 2.8e-10 40.3 0.7 1.2e-07 31.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY94146.1 - 4.2e-09 36.0 0.7 2.4e-05 23.6 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY94146.1 - 7.7e-08 32.5 0.1 2.4e-07 30.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY94146.1 - 2.8e-07 30.1 0.2 3.4e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY94146.1 - 3.6e-05 23.0 0.5 0.027 13.6 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORY94146.1 - 5.2e-05 22.8 0.1 7.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 ORY94146.1 - 0.00011 21.7 0.1 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY94146.1 - 0.00018 20.7 0.3 0.00022 20.4 0.3 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 ORY94146.1 - 0.0002 20.2 0.3 0.0012 17.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 ORY94146.1 - 0.0006 19.8 0.1 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY94146.1 - 0.0042 16.4 0.4 0.0078 15.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY94146.1 - 0.0043 16.4 0.0 0.0064 15.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain GARS_N PF02844.15 ORY94146.1 - 0.018 15.8 0.1 8.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain K_oxygenase PF13434.6 ORY94146.1 - 0.059 12.5 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 ORY94146.1 - 0.18 12.4 1.1 6.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 ORY94147.1 - 5.2e-20 71.0 0.0 1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY94147.1 - 0.00028 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY94147.1 - 0.0023 18.0 0.1 0.0086 16.2 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 ORY94147.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 Limkain b1 G6PD_C PF02781.16 ORY94148.1 - 1.8e-109 365.4 0.0 2.6e-109 364.9 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORY94148.1 - 2.4e-62 210.7 0.2 4.1e-60 203.4 0.1 2.3 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3982 PF13138.6 ORY94148.1 - 0.004 16.9 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3982) TLD PF07534.16 ORY94151.1 - 6.8e-30 104.1 0.0 1.1e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 TLD GREB1 PF15782.5 ORY94151.1 - 0.18 8.9 4.4 0.22 8.6 4.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 ORY94151.1 - 2.7 7.5 7.4 4.5 6.8 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 ORY94153.1 - 8.6e-06 26.4 3.4 0.12 13.3 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY94153.1 - 0.037 14.3 0.0 1.1 9.7 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY94153.1 - 0.094 12.6 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Arrestin_N PF00339.29 ORY94154.1 - 4.9e-16 59.1 0.0 1.3e-15 57.8 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY94154.1 - 5.1e-09 36.7 0.0 3.4e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORY94154.1 - 1.5e-05 24.4 0.1 2.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Rgp1 LDB19 PF13002.7 ORY94154.1 - 0.00012 21.9 0.3 0.0002 21.1 0.0 1.6 2 0 0 2 2 2 1 Arrestin_N terminal like Opi1 PF08618.10 ORY94156.1 - 2.6e-56 191.7 7.8 8.7e-49 166.9 4.8 2.0 1 1 1 2 2 2 2 Transcription factor Opi1 Ipi1_N PF12333.8 ORY94156.1 - 0.13 12.9 3.7 0.36 11.4 3.8 1.8 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Hexokinase_2 PF03727.16 ORY94156.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Hexokinase Pex24p PF06398.11 ORY94157.1 - 4.4e-18 65.4 26.4 1.3e-14 54.0 26.4 3.0 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.22 ORY94157.1 - 2.1e-13 49.9 7.6 3.6e-13 49.2 7.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 ORY94157.1 - 0.075 12.9 8.0 0.19 11.7 5.9 2.5 2 0 0 2 2 2 0 PHD-finger ATP-grasp_2 PF08442.10 ORY94159.1 - 1.7e-78 262.8 0.1 2.9e-78 262.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ORY94159.1 - 7.3e-25 87.6 0.7 1.2e-24 86.8 0.7 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ORY94159.1 - 7.3e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ORY94159.1 - 2.2e-07 30.9 1.6 0.0079 16.0 0.0 3.2 3 0 0 3 3 3 3 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LAMTOR5 PF16672.5 ORY94160.1 - 8e-20 70.6 0.0 8.8e-20 70.4 0.0 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 ORY94160.1 - 3.3e-05 23.6 0.1 4.4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain SRAP PF02586.14 ORY94161.1 - 1.9e-65 220.5 0.0 2.4e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Cys_Met_Meta_PP PF01053.20 ORY94162.1 - 3.4e-157 522.9 1.5 3.8e-157 522.7 1.5 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY94162.1 - 5.7e-10 38.9 0.1 9.1e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY94162.1 - 3.8e-06 26.1 0.5 8.1e-06 25.0 0.4 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY94162.1 - 1.3e-05 24.7 2.2 2.5e-05 23.8 2.2 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORY94162.1 - 0.032 13.5 0.6 0.11 11.7 0.6 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase AidB_N PF18158.1 ORY94163.1 - 3.5e-28 98.5 0.1 6.7e-27 94.3 0.0 2.4 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY94163.1 - 2.9e-22 79.5 0.7 2.9e-22 79.5 0.7 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY94163.1 - 2.3e-16 59.8 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY94163.1 - 1.1e-06 29.0 0.1 3.1e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4229 PF14012.6 ORY94164.1 - 0.035 14.2 0.5 0.049 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Adap_comp_sub PF00928.21 ORY94165.1 - 4.7e-69 232.7 0.0 5.7e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY94165.1 - 1.4e-08 34.8 0.5 7.3e-08 32.5 0.5 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF3876 PF12992.7 ORY94165.1 - 0.07 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) RNA_pol_Rpc34 PF05158.12 ORY94168.1 - 1.3e-89 300.9 0.0 2.1e-89 300.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 ORY94168.1 - 0.051 14.2 0.8 0.52 11.0 0.3 2.3 2 0 0 2 2 2 0 Replication protein A C terminal B-block_TFIIIC PF04182.12 ORY94168.1 - 0.079 13.1 0.8 5.3 7.3 0.1 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC 6PF2K PF01591.18 ORY94169.1 - 9.5e-71 237.6 0.0 1.3e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY94169.1 - 8.5e-28 97.4 0.3 3.3e-27 95.5 0.3 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY94169.1 - 0.0023 18.1 0.0 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 ORY94170.1 - 4.6e-71 238.9 0.0 6.5e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY94170.1 - 1.8e-46 157.6 0.0 2.9e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY94170.1 - 3.7e-20 72.2 0.6 1.2e-19 70.6 0.6 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP_sub_h PF10775.9 ORY94171.1 - 1.3e-21 76.4 1.1 1.7e-21 76.0 1.1 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Uteroglobin PF01099.17 ORY94171.1 - 0.16 12.3 0.2 1.6 9.2 0.0 2.1 2 0 0 2 2 2 0 Uteroglobin family DUF202 PF02656.15 ORY94172.1 - 4.8e-20 71.8 1.6 7.3e-20 71.2 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) GST_N_2 PF13409.6 ORY94173.1 - 5.7e-24 84.2 0.0 5.1e-22 77.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY94173.1 - 6.9e-13 48.4 0.0 1.9e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY94173.1 - 1.8e-07 31.3 0.0 4.2e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY94173.1 - 0.00011 22.3 0.1 0.00028 21.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY94173.1 - 0.00034 20.9 0.0 0.016 15.6 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Cg6151-P PF10233.9 ORY94174.1 - 8.6e-16 58.3 18.8 1.3e-09 38.3 10.1 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein CG6151-P Tropomyosin_1 PF12718.7 ORY94174.1 - 9.1e-15 55.1 36.8 3.2e-10 40.3 19.5 2.2 1 1 1 2 2 2 2 Tropomyosin like UPF0242 PF06785.11 ORY94174.1 - 0.00037 20.6 19.2 0.0011 19.1 17.3 2.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus MAD PF05557.13 ORY94174.1 - 0.0026 16.2 20.1 0.0037 15.7 20.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Tropomyosin PF00261.20 ORY94174.1 - 0.0052 16.2 31.4 0.006 16.0 31.4 1.0 1 0 0 1 1 1 1 Tropomyosin DUF1664 PF07889.12 ORY94174.1 - 0.01 15.9 8.8 0.018 15.1 6.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Taxilin PF09728.9 ORY94174.1 - 0.023 13.9 23.9 0.067 12.4 13.2 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein PI3K_P85_iSH2 PF16454.5 ORY94174.1 - 0.073 12.7 22.7 0.25 10.9 16.6 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF724 PF05266.14 ORY94174.1 - 0.096 12.5 24.0 0.041 13.7 6.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 ORY94174.1 - 0.11 10.0 21.8 0.13 9.7 21.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IFT57 PF10498.9 ORY94174.1 - 0.12 11.3 15.4 0.18 10.7 15.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 ORY94174.1 - 0.13 12.4 30.3 0.48 10.6 30.4 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 ORY94174.1 - 0.26 11.3 16.4 0.61 10.1 16.4 1.5 1 1 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 ORY94174.1 - 0.33 9.8 29.8 0.045 12.6 10.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 ORY94174.1 - 0.36 9.4 10.0 0.47 9.0 10.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A GAS PF13851.6 ORY94174.1 - 0.42 9.9 28.7 1.1 8.6 28.7 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding KELK PF15796.5 ORY94174.1 - 0.44 11.0 27.9 0.098 13.1 18.6 2.2 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 ORY94174.1 - 0.47 10.5 30.7 3.7 7.6 9.9 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 ORY94174.1 - 0.58 9.7 10.5 0.74 9.3 10.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 ORY94174.1 - 0.74 9.9 33.2 0.45 10.6 13.1 2.8 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Borrelia_P83 PF05262.11 ORY94174.1 - 0.83 8.1 19.9 1 7.8 19.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_MLP1_2 PF07926.12 ORY94174.1 - 1.1 9.3 31.2 1 9.4 25.8 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.12 ORY94174.1 - 1.4 9.2 11.2 8.1 6.8 3.8 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG BST2 PF16716.5 ORY94174.1 - 1.7 9.3 25.4 1.3 9.6 17.9 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF3450 PF11932.8 ORY94174.1 - 1.7 7.8 24.0 6.3 6.0 15.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DHR10 PF18595.1 ORY94174.1 - 2 8.5 33.8 0.29 11.2 16.1 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FlxA PF14282.6 ORY94174.1 - 2.1 8.4 22.0 0.64 10.0 4.8 2.2 1 1 1 2 2 2 0 FlxA-like protein Jnk-SapK_ap_N PF09744.9 ORY94174.1 - 2.1 8.5 25.5 3 8.1 25.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 ORY94174.1 - 2.3 8.3 27.2 3 7.9 9.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 ORY94174.1 - 2.5 5.9 13.0 3.6 5.4 13.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HalX PF08663.10 ORY94174.1 - 3.2 8.2 25.0 0.32 11.4 11.8 2.5 1 1 1 2 2 2 0 HalX domain Fez1 PF06818.15 ORY94174.1 - 3.3 8.1 23.2 4.8 7.6 23.2 1.1 1 0 0 1 1 1 0 Fez1 DUF3435 PF11917.8 ORY94174.1 - 4.6 6.1 12.4 5.7 5.8 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4200 PF13863.6 ORY94174.1 - 4.6 7.7 30.1 7.4 7.0 29.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-K PF11802.8 ORY94174.1 - 5.8 6.4 18.8 7.3 6.1 18.8 1.1 1 0 0 1 1 1 0 Centromere-associated protein K BRE1 PF08647.11 ORY94174.1 - 5.8 7.1 28.3 5.2 7.2 17.6 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF334 PF03904.13 ORY94174.1 - 7.7 6.0 12.9 22 4.5 12.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF334) DUF1640 PF07798.11 ORY94175.1 - 8.7e-50 169.2 8.2 1.1e-49 168.9 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.12 ORY94175.1 - 9.9e-05 22.4 4.0 9.9e-05 22.4 4.0 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Cytochrom_B562 PF07361.11 ORY94175.1 - 0.003 18.2 2.4 0.0064 17.1 2.4 1.5 1 0 0 1 1 1 1 Cytochrome b562 MbeB_N PF04837.12 ORY94175.1 - 0.009 16.3 3.3 1.6 9.1 1.3 2.8 1 1 1 2 2 2 1 MbeB-like, N-term conserved region Bcr-Abl_Oligo PF09036.10 ORY94175.1 - 0.061 13.3 0.6 0.2 11.7 0.6 1.9 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain HALZ PF02183.18 ORY94175.1 - 0.075 13.3 1.6 0.075 13.3 1.6 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF2570 PF10828.8 ORY94175.1 - 0.096 12.5 6.3 0.041 13.7 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Rootletin PF15035.6 ORY94175.1 - 0.16 11.9 10.7 0.3 11.1 10.6 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4795 PF16043.5 ORY94175.1 - 0.22 11.1 10.1 0.3 10.7 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Prominin PF05478.11 ORY94175.1 - 0.22 9.4 3.3 0.25 9.3 3.3 1.2 1 0 0 1 1 1 0 Prominin YabA PF06156.13 ORY94175.1 - 0.26 11.9 7.8 0.62 10.7 5.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Golgin_A5 PF09787.9 ORY94175.1 - 0.31 10.4 11.9 0.42 10.0 11.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF724 PF05266.14 ORY94175.1 - 0.35 10.7 11.5 6.6 6.5 11.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) G-gamma PF00631.22 ORY94175.1 - 0.41 10.7 5.2 0.43 10.6 0.4 3.0 3 0 0 3 3 3 0 GGL domain Tho2 PF11262.8 ORY94175.1 - 0.46 9.6 6.3 0.73 9.0 5.9 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF5082 PF16888.5 ORY94175.1 - 0.52 10.6 10.2 0.87 9.9 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) XhlA PF10779.9 ORY94175.1 - 0.58 10.4 9.7 2.4 8.4 4.5 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 ORY94175.1 - 0.84 9.7 5.5 0.92 9.5 3.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lzipper-MIP1 PF14389.6 ORY94175.1 - 0.96 9.8 8.9 1.1 9.6 4.9 2.8 2 2 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Remorin_C PF03763.13 ORY94175.1 - 1.1 9.1 6.9 1.8 8.5 5.8 1.8 1 1 1 2 2 2 0 Remorin, C-terminal region COG5 PF10392.9 ORY94175.1 - 1.2 9.4 11.6 3.7 7.7 2.9 3.3 1 1 1 3 3 3 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 ORY94175.1 - 1.2 9.5 8.3 1.5 9.3 1.3 3.3 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Siah-Interact_N PF09032.11 ORY94175.1 - 1.4 9.3 12.7 2.5 8.5 5.6 2.8 1 1 2 3 3 3 0 Siah interacting protein, N terminal Fungal_TACC PF12709.7 ORY94175.1 - 1.6 9.2 9.4 5.9 7.4 3.7 2.8 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cnn_1N PF07989.11 ORY94175.1 - 3.2 8.0 12.0 1.2 9.4 4.6 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1843 PF08898.10 ORY94175.1 - 3.3 8.3 5.0 0.6 10.7 0.2 2.3 3 1 0 3 3 1 0 Domain of unknown function (DUF1843) UQ_con PF00179.26 ORY94176.1 - 1.3e-14 54.0 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY94176.1 - 0.005 17.1 0.0 0.0055 17.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 ORY94176.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 UEV domain CTP_transf_like PF01467.26 ORY94177.1 - 6e-30 104.3 0.0 7.4e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like ABC_tran PF00005.27 ORY94178.1 - 6.1e-16 59.2 0.2 4.5e-15 56.4 0.2 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY94178.1 - 4.1e-11 43.3 2.3 7.4e-05 22.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY94178.1 - 0.00071 19.3 0.0 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ORY94178.1 - 0.0031 17.7 0.1 0.015 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 ORY94178.1 - 0.0057 16.1 0.1 3.1 7.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY94178.1 - 0.014 15.4 0.2 0.028 14.5 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 ORY94178.1 - 0.021 15.1 0.3 0.06 13.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY94178.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 ORY94178.1 - 0.023 15.2 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY94178.1 - 0.046 13.3 0.3 0.14 11.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY94178.1 - 0.049 14.0 0.3 0.07 13.5 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 ORY94178.1 - 0.058 13.8 0.1 9.4 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORY94178.1 - 0.083 12.6 0.2 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ORY94178.1 - 0.11 13.0 0.1 0.4 11.1 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 ORY94178.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY94178.1 - 0.17 12.3 0.2 4.1 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 ORY94178.1 - 0.17 11.1 0.4 0.52 9.6 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 ORY94178.1 - 0.29 11.4 0.9 0.86 9.9 0.9 2.0 1 1 0 1 1 1 0 AAA domain HPP PF04982.13 ORY94179.1 - 5.9e-41 139.5 5.6 5.9e-41 139.5 5.6 1.8 2 0 0 2 2 2 1 HPP family Bax1-I PF01027.20 ORY94179.1 - 0.074 12.9 10.8 0.017 14.9 5.0 2.1 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 NmrA PF05368.13 ORY94180.1 - 1.2e-16 61.0 0.0 1.6e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY94180.1 - 3.6e-14 53.1 0.0 5.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORY94180.1 - 0.00058 20.1 0.0 0.00091 19.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORY94180.1 - 0.001 18.6 0.1 0.0026 17.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY94180.1 - 0.0086 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ORY94180.1 - 0.032 14.7 0.5 0.11 12.9 0.5 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 ORY94180.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 ORY94180.1 - 0.083 12.0 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein TrkA_N PF02254.18 ORY94180.1 - 0.086 13.1 0.1 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain LAMTOR PF15454.6 ORY94181.1 - 0.0022 18.6 1.8 0.0037 17.9 1.2 1.7 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator YjbF PF11102.8 ORY94181.1 - 0.015 15.1 0.3 0.031 14.0 0.1 1.6 2 0 0 2 2 2 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF DUF4750 PF15938.5 ORY94182.1 - 0.079 12.6 1.3 0.13 12.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) zf-RING_12 PF17976.1 ORY94183.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SKN1 PF03935.15 ORY94184.1 - 0.0034 15.8 0.0 0.0047 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TRIQK PF15168.6 ORY94184.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Mre11_DNA_bind PF04152.14 ORY94186.1 - 1.1e-39 136.4 0.0 3e-39 135.0 0.0 1.7 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 ORY94186.1 - 5.5e-16 59.7 0.1 1e-15 58.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY94186.1 - 2.3e-07 31.1 0.0 6e-06 26.5 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Spt20 PF12090.8 ORY94187.1 - 0.0052 16.4 12.2 0.01 15.4 12.2 1.5 1 0 0 1 1 1 1 Spt20 family Spore_YhcN_YlaJ PF09580.10 ORY94187.1 - 0.14 12.2 7.7 0.084 13.0 3.3 2.3 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) MPM1 PF17234.2 ORY94187.1 - 0.17 12.1 10.5 0.52 10.6 10.5 1.8 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Sporozoite_P67 PF05642.11 ORY94187.1 - 1.4 7.0 9.2 2.4 6.1 9.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CLN3 PF02487.17 ORY94187.1 - 7.2 5.5 4.7 11 4.9 4.7 1.3 1 0 0 1 1 1 0 CLN3 protein DUF3464 PF11947.8 ORY94187.1 - 7.9 6.2 6.8 33 4.2 6.8 2.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Zip PF02535.22 ORY94187.1 - 9.2 5.4 7.5 16 4.6 7.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter HAP1_N PF04849.13 ORY94188.1 - 0.065 12.4 11.6 0.33 10.1 11.4 2.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region HSP70 PF00012.20 ORY94189.1 - 1.8e-07 29.7 0.0 1.2e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORY94189.1 - 0.24 10.2 0.0 0.54 9.0 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein DNA_binding_1 PF01035.20 ORY94190.1 - 1.8e-22 79.2 0.0 2.8e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4732 PF15876.5 ORY94190.1 - 0.17 12.0 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) UbiA PF01040.18 ORY94191.1 - 1.9e-55 187.9 16.9 2.2e-55 187.7 16.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family HsbA PF12296.8 ORY94192.1 - 0.04 14.3 0.1 0.069 13.6 0.0 1.5 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Scs3p PF10261.9 ORY94194.1 - 1.2e-48 165.7 28.9 2.4e-38 132.1 12.4 2.7 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Sin3a_C PF16879.5 ORY94197.1 - 1.6e-47 162.6 11.1 1.6e-47 162.6 11.1 3.9 5 0 0 5 5 5 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY94197.1 - 2.4e-42 142.8 11.2 8.4e-17 61.1 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY94197.1 - 2.3e-39 133.4 2.2 2.3e-39 133.4 2.2 2.9 2 0 0 2 2 2 1 Sin3 family co-repressor Nexin_C PF08628.12 ORY94197.1 - 0.071 13.7 1.3 1.4 9.6 0.0 3.6 2 2 1 3 3 3 0 Sorting nexin C terminal Ku PF02735.16 ORY94198.1 - 2.1e-43 148.4 0.0 3.3e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ORY94198.1 - 3.5e-33 115.2 0.0 5.1e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 ORY94198.1 - 2.1e-15 57.2 0.2 6.5e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm BLOC1_2 PF10046.9 ORY94199.1 - 1.2e-23 83.2 4.2 1.6e-23 82.8 4.2 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rootletin PF15035.6 ORY94199.1 - 0.00094 19.3 1.8 0.0013 18.8 1.8 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF1759 PF03564.15 ORY94199.1 - 0.0045 16.9 0.7 0.0071 16.3 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1759) Fib_alpha PF08702.10 ORY94199.1 - 0.03 14.5 1.8 0.043 14.0 1.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY94199.1 - 0.045 14.2 1.0 0.084 13.3 0.9 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 ORY94199.1 - 0.051 13.7 1.4 3.1 7.9 0.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 ORY94199.1 - 0.06 13.4 1.6 0.082 12.9 1.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 ORY94199.1 - 0.067 13.4 4.4 0.11 12.7 4.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding tRNA-synt_1d PF00750.19 ORY94199.1 - 0.068 12.1 0.5 0.083 11.8 0.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) DUF1043 PF06295.12 ORY94199.1 - 0.09 12.8 5.3 0.082 12.9 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) THOC7 PF05615.13 ORY94199.1 - 0.19 12.0 4.2 0.32 11.3 4.2 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 CREPT PF16566.5 ORY94199.1 - 0.28 11.3 4.7 0.84 9.8 2.5 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PAP_central PF04928.17 ORY94200.1 - 6.7e-34 117.0 0.0 1.4e-33 115.9 0.0 1.4 1 1 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY94200.1 - 6.1e-11 42.2 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY94200.1 - 0.0023 18.2 0.0 0.0054 17.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain 2OG-FeII_Oxy_3 PF13640.6 ORY94201.1 - 9.2e-05 23.3 0.0 0.00014 22.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.15 ORY94201.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase ABC_membrane_2 PF06472.15 ORY94202.1 - 3.2e-60 203.8 0.5 4.9e-60 203.2 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY94202.1 - 4.3e-20 72.6 0.0 7.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY94202.1 - 6.8e-06 26.1 0.0 2.8e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY94202.1 - 9.1e-05 22.0 0.0 0.0045 16.5 0.0 2.4 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY94202.1 - 0.00069 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY94202.1 - 0.00076 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY94202.1 - 0.0013 19.3 0.0 0.0023 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 ORY94202.1 - 0.003 17.2 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY94202.1 - 0.0034 17.1 0.0 0.008 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORY94202.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 ORY94202.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY94202.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2813 PF11398.8 ORY94202.1 - 0.04 13.2 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) MMR_HSR1 PF01926.23 ORY94202.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3584 PF12128.8 ORY94202.1 - 0.33 8.4 0.0 0.49 7.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LSM PF01423.22 ORY94203.1 - 5.7e-18 64.4 0.1 7.1e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY94203.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Hfq protein Ras PF00071.22 ORY94204.1 - 2.2e-54 183.5 0.0 2.5e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY94204.1 - 3.1e-22 79.0 0.0 4.2e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY94204.1 - 7.6e-08 32.0 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Mso1_Sec1_bdg PF14475.6 ORY94205.1 - 8.6e-09 34.9 0.2 2.8e-08 33.2 0.2 1.9 1 0 0 1 1 1 1 Sec1-binding region of Mso1 AA_permease PF00324.21 ORY94207.1 - 4.2e-140 467.5 37.2 5.1e-140 467.2 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY94207.1 - 1.7e-46 159.0 41.0 2.1e-46 158.6 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease TNFR_16_TM PF18422.1 ORY94207.1 - 0.096 12.7 0.3 0.096 12.7 0.3 4.0 5 0 0 5 5 5 0 Tumor necrosis factor receptor member 16 trans-membrane domain Zeta_toxin PF06414.12 ORY94208.1 - 7e-08 32.0 0.0 1.4e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 ORY94208.1 - 2.1e-06 27.9 1.1 3.5e-05 24.0 1.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY94208.1 - 4.4e-06 27.2 0.1 1.7e-05 25.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY94208.1 - 7.3e-06 26.6 0.7 1.4e-05 25.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.6 ORY94208.1 - 0.00018 21.8 0.0 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY94208.1 - 0.0081 16.7 0.5 0.028 14.9 0.1 2.0 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 ORY94208.1 - 0.0094 15.5 0.2 0.026 14.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORY94208.1 - 0.016 15.7 0.0 0.046 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ORY94208.1 - 0.017 15.5 0.1 0.049 14.1 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY94208.1 - 0.026 14.4 0.0 0.11 12.4 0.0 2.0 3 0 0 3 3 2 0 RsgA GTPase RNA_helicase PF00910.22 ORY94208.1 - 0.026 14.9 0.1 0.066 13.6 0.1 1.7 1 1 0 1 1 1 0 RNA helicase PRK PF00485.18 ORY94208.1 - 0.029 14.1 0.1 0.08 12.7 0.1 1.8 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 ORY94208.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain PAC4 PF16093.5 ORY94208.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 AAA_5 PF07728.14 ORY94208.1 - 0.061 13.3 0.9 0.13 12.2 0.1 2.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 ORY94208.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 ORY94208.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 ORY94208.1 - 0.07 13.2 0.5 0.32 11.1 0.5 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family APS_kinase PF01583.20 ORY94208.1 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CPT PF07931.12 ORY94208.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 ORY94208.1 - 0.13 12.1 0.1 0.48 10.2 0.1 1.9 1 1 0 1 1 1 0 Deoxynucleoside kinase CbiA PF01656.23 ORY94208.1 - 0.14 12.2 0.5 0.28 11.2 0.5 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 ORY94208.1 - 0.22 11.5 1.2 0.33 10.9 0.3 1.9 2 1 0 2 2 1 0 NACHT domain AAA_22 PF13401.6 ORY94208.1 - 0.3 11.4 1.8 0.67 10.2 0.7 2.2 2 1 0 2 2 2 0 AAA domain Aminotran_3 PF00202.21 ORY94209.1 - 9.5e-119 396.7 0.0 1.1e-118 396.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY94209.1 - 0.00024 20.4 0.0 0.0005 19.3 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II LGT PF01790.18 ORY94209.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase dsDNA_bind PF01984.20 ORY94211.1 - 2.2e-29 102.0 4.3 2.6e-29 101.7 4.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TPR_20 PF14561.6 ORY94211.1 - 0.00077 19.7 2.7 0.0011 19.2 2.7 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat LETM1 PF07766.13 ORY94212.1 - 0.023 14.0 1.4 0.023 14.1 1.4 1.0 1 0 0 1 1 1 0 LETM1-like protein TctA PF01970.16 ORY94214.1 - 0.018 13.8 3.3 0.021 13.6 2.5 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DUF2985 PF11204.8 ORY94214.1 - 0.023 14.8 0.9 0.19 11.9 0.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2985) HRG PF16954.5 ORY94214.1 - 0.05 14.0 0.2 0.05 14.0 0.2 3.7 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Tetraspanin PF00335.20 ORY94214.1 - 0.12 12.1 12.8 0.11 12.2 8.3 2.1 1 1 1 2 2 2 0 Tetraspanin family p450 PF00067.22 ORY94215.1 - 4.7e-89 299.2 0.0 6e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_primase_S PF01896.19 ORY94216.1 - 3.9e-59 199.7 0.1 8.7e-59 198.5 0.1 1.6 1 0 0 1 1 1 1 DNA primase small subunit 4HBT_2 PF13279.6 ORY94216.1 - 0.1 13.1 0.0 0.98 9.9 0.0 2.1 1 1 0 1 1 1 0 Thioesterase-like superfamily PCI PF01399.27 ORY94217.1 - 4.6e-16 59.2 0.4 1.7e-15 57.4 0.0 2.2 3 0 0 3 3 3 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 ORY94217.1 - 0.00013 22.1 0.0 0.00039 20.5 0.0 1.8 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain CSN8_PSD8_EIF3K PF10075.9 ORY94217.1 - 0.0023 17.9 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAP PF02037.27 ORY94218.1 - 4.1e-12 45.5 0.1 6.9e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 SAP domain TFIIA PF03153.13 ORY94218.1 - 0.053 13.5 19.4 0.061 13.3 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RusA PF05866.11 ORY94218.1 - 0.94 10.0 3.1 2.4 8.7 0.8 2.1 1 1 1 2 2 2 0 Endodeoxyribonuclease RusA DUF3123 PF11321.8 ORY94218.1 - 1.4 9.6 5.8 0.44 11.2 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) FANC_SAP PF18081.1 ORY94218.1 - 7.8 6.7 6.4 0.63 10.2 0.2 2.5 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain BPL_LplA_LipB PF03099.19 ORY94219.1 - 1.8e-09 37.6 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NAD_binding_10 PF13460.6 ORY94221.1 - 5.6e-13 49.2 0.0 7.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY94221.1 - 2.2e-11 43.7 0.0 5.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family TrkA_N PF02254.18 ORY94221.1 - 6.1e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 ORY94221.1 - 0.00056 19.5 0.0 0.0011 18.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY94221.1 - 0.00061 19.9 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 ORY94221.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 ORY94221.1 - 0.0014 19.2 0.0 0.012 16.2 0.0 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ORY94221.1 - 0.0032 17.7 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ORY94221.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ORY94221.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ORY94221.1 - 0.16 12.4 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_S8 PF00082.22 ORY94222.1 - 3.9e-35 121.6 10.5 7.3e-35 120.7 10.5 1.4 1 1 0 1 1 1 1 Subtilase family E1-E2_ATPase PF00122.20 ORY94223.1 - 7.7e-26 90.7 2.1 8.4e-26 90.6 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY94223.1 - 1.5e-10 41.7 0.4 0.00022 21.6 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY94223.1 - 2.9e-05 23.7 0.9 8.4e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY94223.1 - 0.0023 18.0 0.0 0.0064 16.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY94223.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AMP-binding PF00501.28 ORY94224.1 - 6.9e-37 127.0 0.0 1.7e-36 125.8 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORY94224.1 - 8.9e-35 120.1 0.0 2e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 ORY94224.1 - 3.6e-11 43.2 0.3 8.2e-11 42.1 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORY94224.1 - 2.7e-07 30.3 0.0 1.7e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY94224.1 - 0.031 13.4 0.0 0.16 11.1 0.0 2.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein AMP-binding PF00501.28 ORY94226.1 - 7.2e-40 136.9 0.0 2.7e-39 135.0 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORY94226.1 - 4.5e-35 121.1 0.0 2e-34 118.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 ORY94226.1 - 4.4e-12 46.2 0.5 1e-11 45.0 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORY94226.1 - 1.9e-07 30.8 0.0 1.7e-06 27.7 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY94226.1 - 0.02 14.0 0.0 0.16 11.1 0.0 2.4 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein HAT_KAT11 PF08214.11 ORY94228.1 - 5.2e-31 108.2 0.6 2.2e-30 106.1 0.6 1.7 1 1 0 1 1 1 1 Histone acetylation protein AAA PF00004.29 ORY94229.1 - 7.6e-17 62.0 0.0 1.6e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY94229.1 - 4.7e-11 43.1 0.0 1.9e-10 41.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY94229.1 - 4.8e-10 40.1 0.1 3.4e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 ORY94229.1 - 6e-10 39.1 1.0 1.4e-09 38.0 0.7 1.7 1 1 0 1 1 1 1 AAA lid domain Cdc6_C PF09079.11 ORY94229.1 - 4.2e-07 29.8 0.0 2.2e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain ATPase_2 PF01637.18 ORY94229.1 - 0.00012 22.0 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ORY94229.1 - 0.00013 22.3 0.8 0.0011 19.4 0.8 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORY94229.1 - 0.00071 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 ORY94229.1 - 0.0017 18.2 0.1 0.0037 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY94229.1 - 0.0094 16.0 0.2 0.069 13.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY94229.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.9 2 1 1 3 3 3 0 NACHT domain AAA_assoc_2 PF16193.5 ORY94229.1 - 0.018 15.3 1.0 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA C-terminal domain DUF4031 PF13223.6 ORY94229.1 - 0.026 14.7 0.1 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) TIP49 PF06068.13 ORY94229.1 - 0.03 13.5 0.4 0.58 9.3 0.0 2.6 3 0 0 3 3 3 0 TIP49 P-loop domain FAST_1 PF06743.15 ORY94229.1 - 0.09 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 KAP_NTPase PF07693.14 ORY94229.1 - 0.093 11.9 0.4 1.8 7.7 0.4 2.0 1 1 1 2 2 2 0 KAP family P-loop domain PIF1 PF05970.14 ORY94229.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase TsaE PF02367.17 ORY94229.1 - 0.1 12.6 0.1 0.68 9.9 0.0 2.3 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ORY94229.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 ORY94229.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Sel1 PF08238.12 ORY94230.1 - 1.1e-10 41.8 19.3 5.1e-05 23.8 0.1 6.8 8 0 0 8 8 8 4 Sel1 repeat Tom7 PF08038.12 ORY94230.1 - 0.18 11.5 0.6 0.51 10.0 0.1 1.9 2 0 0 2 2 2 0 TOM7 family TPR_7 PF13176.6 ORY94230.1 - 1.4 9.1 7.5 5.4 7.3 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY94230.1 - 5.2 8.2 14.6 30 5.8 1.6 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat DUF1353 PF07087.11 ORY94231.1 - 0.014 15.1 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Ripply PF14998.6 ORY94231.1 - 0.14 12.8 0.2 0.25 12.0 0.2 1.7 1 1 0 1 1 1 0 Transcription Regulator Tachystatin_B PF11478.8 ORY94233.1 - 0.00063 19.6 0.8 0.001 19.0 0.8 1.4 1 0 0 1 1 1 1 Antimicrobial chitin binding protein tachystatin B Polysacc_deac_1 PF01522.21 ORY94234.1 - 3.7e-24 85.0 0.1 7.4e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase V_cholerae_RfbT PF05575.11 ORY94234.1 - 0.045 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein HMG_box PF00505.19 ORY94235.1 - 3.2e-18 65.9 4.9 6.2e-18 65.0 4.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY94235.1 - 4.5e-08 33.6 3.1 1e-07 32.4 3.1 1.5 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.14 ORY94235.1 - 0.0014 18.7 1.0 0.0014 18.7 1.0 2.5 3 0 0 3 3 3 1 Cytochrome c oxidase subunit IV MATalpha_HMGbox PF04769.12 ORY94235.1 - 0.09 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box SR-25 PF10500.9 ORY94235.1 - 1.2 8.7 16.4 0.1 12.2 11.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Polysacc_deac_1 PF01522.21 ORY94236.1 - 4.4e-23 81.5 0.0 7.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SPX PF03105.19 ORY94236.1 - 0.53 10.1 3.4 0.21 11.5 0.9 1.6 2 0 0 2 2 2 0 SPX domain MT-A70 PF05063.14 ORY94237.1 - 1.9e-39 135.4 0.0 3.2e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 MT-A70 HATPase_c PF02518.26 ORY94238.1 - 3.6e-29 101.5 0.1 1e-28 100.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY94238.1 - 3.1e-22 78.9 0.3 1.6e-20 73.3 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORY94238.1 - 1e-16 60.7 0.1 4.5e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 ORY94238.1 - 9.9e-16 58.6 1.1 8e-15 55.6 0.0 3.1 4 0 0 4 4 3 1 AAA ATPase domain Pkinase PF00069.25 ORY94238.1 - 9.2e-15 54.7 0.0 2.3e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94238.1 - 2.6e-08 33.5 0.0 4.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_3 PF13492.6 ORY94238.1 - 4.5e-06 27.0 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ORY94238.1 - 5.1e-06 27.2 0.0 1.5e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 ORY94238.1 - 8.1e-06 26.2 0.0 2.4e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.6 ORY94238.1 - 0.0004 20.7 0.0 0.006 16.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY94238.1 - 0.00063 19.0 2.0 0.065 12.4 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain ABC_tran PF00005.27 ORY94238.1 - 0.00095 19.7 0.0 0.013 16.0 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 ORY94238.1 - 0.022 14.5 0.0 0.065 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY94238.1 - 0.03 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 ORY94238.1 - 0.036 14.0 0.4 0.21 11.5 0.1 2.6 2 1 0 2 2 2 0 NACHT domain DUF87 PF01935.17 ORY94238.1 - 0.042 13.9 0.4 0.27 11.3 0.0 2.6 4 0 0 4 4 3 0 Helicase HerA, central domain ATPase_2 PF01637.18 ORY94238.1 - 0.045 13.7 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 ORY94238.1 - 0.064 13.3 0.0 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY94238.1 - 0.08 13.5 0.0 0.31 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain Pkinase PF00069.25 ORY94239.1 - 2.2e-60 204.3 0.0 9.9e-39 133.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94239.1 - 4.2e-28 98.3 0.0 5.2e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 ORY94239.1 - 2e-13 50.5 0.5 7.7e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.6 ORY94239.1 - 0.0055 16.0 0.1 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY94239.1 - 0.012 15.5 0.5 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY94239.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PAS PF00989.25 ORY94239.1 - 0.099 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold C2 PF00168.30 ORY94240.1 - 1.3e-11 44.6 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 C2 domain K_channel_TID PF07941.11 ORY94241.1 - 0.1 13.0 2.5 0.23 11.9 2.5 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Steroid_dh PF02544.16 ORY94242.1 - 1.6e-35 122.3 6.6 2.6e-35 121.6 6.6 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase YukD PF08817.10 ORY94242.1 - 0.00047 20.8 0.0 0.00068 20.3 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 ORY94242.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY94242.1 - 0.023 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BID PF06393.11 ORY94243.1 - 0.017 14.7 0.2 0.024 14.2 0.2 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) STI1 PF17830.1 ORY94243.1 - 0.058 13.3 1.2 5.5 7.0 0.1 2.6 2 1 1 3 3 3 0 STI1 domain FAM60A PF15396.6 ORY94244.1 - 0.13 12.3 3.2 0.15 12.1 3.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pkinase PF00069.25 ORY94245.1 - 2.9e-53 180.9 0.0 3.5e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94245.1 - 8.9e-36 123.5 0.0 1.1e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY94245.1 - 1.8e-07 30.8 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY94245.1 - 3.7e-05 22.7 0.0 5.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORY94245.1 - 0.056 12.5 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BAR PF03114.18 ORY94246.1 - 6.4e-34 117.7 9.1 8.2e-34 117.3 9.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY94246.1 - 2e-15 56.1 0.1 3.7e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY94246.1 - 3.3e-11 42.9 0.0 5.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY94246.1 - 3.8e-09 36.1 0.0 6.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FAM76 PF16046.5 ORY94246.1 - 0.29 10.5 6.3 0.14 11.5 1.9 2.0 2 0 0 2 2 2 0 FAM76 protein Vps5 PF09325.10 ORY94246.1 - 0.37 10.3 5.6 0.41 10.2 2.6 2.1 2 0 0 2 2 2 0 Vps5 C terminal like FUSC PF04632.12 ORY94246.1 - 0.53 8.8 2.2 0.69 8.4 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4477 PF14780.6 ORY94246.1 - 0.98 9.0 3.5 5 6.7 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Abhydrolase_1 PF00561.20 ORY94247.1 - 5.9e-13 49.0 0.2 1.3e-12 47.9 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY94247.1 - 5.2e-12 45.5 0.0 1.1e-11 44.5 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY94247.1 - 1.5e-10 42.1 0.3 1.9e-10 41.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY94247.1 - 9.2e-08 31.8 0.8 0.0023 17.5 0.2 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY94247.1 - 0.0029 17.2 2.9 0.016 14.8 2.9 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 ORY94247.1 - 0.0053 16.4 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) NDUF_B7 PF05676.13 ORY94248.1 - 3.6e-30 103.5 4.2 4e-30 103.3 4.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 ORY94248.1 - 0.0064 16.5 4.4 0.0084 16.1 4.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like AHL_synthase PF17327.2 ORY94248.1 - 0.0098 14.9 0.1 0.011 14.8 0.1 1.0 1 0 0 1 1 1 1 Acyl homoserine lactone synthase GRAM PF02893.20 ORY94249.1 - 4e-28 97.6 0.0 1.6e-14 53.7 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 ORY94249.1 - 6.9e-27 94.2 0.0 1.3e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 ORY94249.1 - 3.9e-10 40.2 0.1 1.4e-09 38.4 0.1 2.0 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 ORY94249.1 - 7.9e-08 31.5 0.0 1.7e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 ORY94249.1 - 7.6e-06 26.3 1.4 0.00062 20.2 0.2 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 ORY94249.1 - 0.0082 16.4 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_tran_28_C PF04101.16 ORY94249.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Mito_carr PF00153.27 ORY94250.1 - 8.3e-67 221.2 2.8 6.6e-23 80.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Carn_acyltransf PF00755.20 ORY94251.1 - 4e-188 626.8 0.0 6.4e-188 626.1 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DEAD PF00270.29 ORY94252.1 - 1.3e-38 132.6 0.4 3e-38 131.3 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY94252.1 - 2.8e-23 82.4 0.1 1.1e-21 77.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY94252.1 - 9.2e-10 38.8 0.1 1.9e-09 37.7 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY94252.1 - 0.0021 18.3 0.1 0.018 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF2967 PF11179.8 ORY94253.1 - 0.027 12.6 5.6 0.033 12.3 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Presenilin PF01080.17 ORY94253.1 - 0.17 10.6 5.1 0.23 10.2 5.1 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 ORY94253.1 - 0.25 10.6 15.9 0.29 10.4 15.9 1.2 1 0 0 1 1 1 0 BUD22 DUF2052 PF09747.9 ORY94253.1 - 3.1 7.9 19.5 5.8 7.0 19.5 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PI3K_1B_p101 PF10486.9 ORY94253.1 - 3.8 5.2 10.1 4.3 5.0 10.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNase_P_p30 PF01876.16 ORY94254.1 - 9.7e-28 97.1 0.0 1.9e-27 96.2 0.0 1.4 1 1 1 2 2 2 1 RNase P subunit p30 UCH PF00443.29 ORY94255.1 - 5.8e-46 157.1 0.0 7.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY94255.1 - 1.5e-12 47.8 2.6 3.6e-10 39.9 2.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORY94255.1 - 4e-09 36.1 0.0 9.1e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 ORY94255.1 - 0.013 15.0 0.1 0.037 13.5 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3020 PF11223.8 ORY94256.1 - 8.9e-17 61.3 2.2 1.8e-16 60.3 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3020) zf-C2H2 PF00096.26 ORY94256.1 - 0.023 15.1 0.1 0.067 13.7 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type NPL4 PF05021.15 ORY94257.1 - 2.6e-121 404.7 0.0 3.4e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 ORY94257.1 - 1.2e-67 226.6 0.1 2.7e-67 225.4 0.1 1.7 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 ORY94257.1 - 6.4e-09 36.2 0.0 1.4e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Gpr1_Fun34_YaaH PF01184.19 ORY94259.1 - 4e-72 242.2 19.2 5e-72 241.8 19.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 ORY94259.1 - 1.6 9.2 22.2 0.43 11.1 1.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF202) YabA PF06156.13 ORY94262.1 - 0.15 12.7 3.5 0.17 12.5 2.1 1.7 2 0 0 2 2 2 0 Initiation control protein YabA AATF-Che1 PF13339.6 ORY94262.1 - 0.26 12.0 6.1 0.27 11.9 3.8 2.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor RVT_1 PF00078.27 ORY94264.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crust_neurohorm PF01147.17 ORY94265.1 - 0.035 13.9 0.2 0.076 12.9 0.2 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Exo_endo_phos_2 PF14529.6 ORY94364.1 - 3e-16 59.3 0.2 7.4e-16 58.1 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 ORY94364.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family GTP_EFTU PF00009.27 ORY94366.1 - 8.6e-36 123.3 8.4 2.5e-35 121.8 3.6 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY94366.1 - 7.5e-31 106.4 3.8 2.9e-30 104.5 3.0 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ORY94366.1 - 1.3e-10 41.4 0.1 4.5e-10 39.6 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORY94366.1 - 2.2e-08 34.4 1.8 0.0005 20.4 0.1 4.0 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Arf PF00025.21 ORY94366.1 - 0.00017 21.1 0.6 0.00045 19.7 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 ORY94366.1 - 0.00022 20.8 1.9 0.00049 19.6 0.2 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.6 ORY94366.1 - 0.0011 18.8 3.6 0.37 10.7 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 4 IF2_N PF04760.15 ORY94366.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.9 ORY94366.1 - 0.006 16.3 0.2 0.025 14.3 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 ORY94366.1 - 0.0074 15.7 0.1 0.0074 15.7 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORY94366.1 - 0.0086 16.0 7.2 0.05 13.5 0.1 3.0 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 ORY94366.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase eIF3m_C_helix PF18005.1 ORY94366.1 - 0.099 12.4 0.8 0.24 11.1 0.8 1.7 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix DUF1366 PF07104.11 ORY94366.1 - 0.96 9.2 5.1 11 5.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Dynamin_N PF00350.23 ORY94366.1 - 1.3 9.0 8.0 13 5.8 0.0 4.0 3 1 1 4 4 4 0 Dynamin family MeaB PF03308.16 ORY94366.1 - 4.6 6.1 11.3 0.072 12.1 2.2 2.5 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 ORY94366.1 - 7.2 7.1 0.0 7.2 7.1 0.0 4.1 4 1 0 4 4 4 0 AAA domain zf-UBR PF02207.20 ORY94367.1 - 6.3e-20 71.1 12.6 6.3e-20 71.1 12.6 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 ORY94367.1 - 1.9e-13 50.0 0.1 6e-13 48.4 0.1 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 ORY94367.1 - 0.0015 18.5 0.3 0.0015 18.5 0.3 3.6 4 1 0 4 4 4 1 zinc-RING finger domain UTP15_C PF09384.10 ORY94368.1 - 1.7e-45 154.3 0.2 3.3e-45 153.4 0.2 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 ORY94368.1 - 8e-24 83.5 1.5 0.00018 22.2 0.1 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY94368.1 - 2e-09 37.6 0.1 0.046 14.0 0.0 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY94368.1 - 0.00073 18.3 1.5 0.71 8.4 0.1 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY94368.1 - 0.0066 15.5 0.4 0.5 9.3 0.1 3.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L27A PF00828.19 ORY94369.1 - 2e-20 73.8 0.2 2.6e-20 73.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ubiquitin PF00240.23 ORY94370.1 - 3.2e-102 334.4 12.5 1.4e-33 114.4 0.5 3.1 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 ORY94370.1 - 1.5e-47 159.3 13.6 2.2e-15 56.2 0.7 3.2 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY94370.1 - 3.4e-17 62.7 5.2 0.00049 20.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain zf-AN1 PF01428.16 ORY94370.1 - 5.7e-12 45.6 4.2 8.8e-12 45.0 4.2 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger TBK1_ULD PF18396.1 ORY94370.1 - 7.3e-12 45.0 1.0 0.03 14.2 0.0 3.3 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY94370.1 - 2.5e-11 43.6 0.6 0.024 14.7 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY94370.1 - 4.7e-11 42.9 3.5 0.033 14.5 0.1 3.2 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 ORY94370.1 - 1e-09 38.9 1.0 0.073 13.6 0.1 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY94370.1 - 3.4e-07 30.2 0.2 0.78 9.5 0.0 3.2 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 ORY94370.1 - 3.5e-05 23.8 16.3 17 5.6 0.2 6.1 6 0 0 6 6 6 0 Ubiquitin-like domain DUF2870 PF11069.8 ORY94370.1 - 0.00023 21.5 0.0 6.9 7.1 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 ORY94370.1 - 0.00029 20.9 0.9 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 ORY94370.1 - 0.00051 19.8 1.7 12 5.8 0.0 3.4 3 0 0 3 3 3 0 ACT domain Methyltrans_RNA PF04452.14 ORY94370.1 - 0.00053 19.4 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 ORY94370.1 - 0.0016 19.2 1.2 30 5.5 0.0 3.6 4 0 0 4 4 4 0 Bacterial Ig domain DUF969 PF06149.12 ORY94370.1 - 0.0034 16.8 0.0 18 4.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) TmoB PF06234.12 ORY94370.1 - 0.0039 17.2 0.0 31 4.8 0.0 3.6 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 ORY94370.1 - 0.0068 16.5 1.2 7.5 6.7 0.0 3.1 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_4 PF13291.6 ORY94370.1 - 0.032 14.8 0.3 78 4.0 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 ORY94370.1 - 0.098 13.2 0.0 1.5e+02 3.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF493) ProRS-C_2 PF09181.10 ORY94370.1 - 0.12 12.5 2.4 68 3.7 0.1 3.3 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Plexin_cytopl PF08337.12 ORY94370.1 - 0.29 9.8 9.1 23 3.5 0.3 4.3 3 1 0 4 4 4 0 Plexin cytoplasmic RasGAP domain YcgR_2 PF12945.7 ORY94370.1 - 0.4 10.8 2.2 31 4.8 0.1 3.2 3 0 0 3 3 3 0 Flagellar protein YcgR Tash_PEST PF07708.11 ORY94370.1 - 0.43 10.8 18.4 6.6 7.0 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif FlgD_ig PF13860.6 ORY94370.1 - 0.61 10.0 4.9 46 4.0 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 ORY94370.1 - 1.4 9.4 4.9 63 4.1 0.1 3.1 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain PI3K_p85B PF02192.16 ORY94370.1 - 2.3 8.0 4.6 1e+02 2.7 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain HlyIII PF03006.20 ORY94371.1 - 2.3e-57 194.3 22.8 3e-57 193.9 22.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related Tom37 PF10568.9 ORY94372.1 - 2e-22 79.8 0.0 3.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 ORY94372.1 - 2.3e-20 73.2 0.0 4.9e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ORY94372.1 - 1.3e-16 60.1 0.0 3.1e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY94372.1 - 4.7e-08 33.0 0.0 9.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNase_P_p30 PF01876.16 ORY94374.1 - 2.3e-43 148.2 0.6 6.7e-43 146.6 0.0 1.7 2 0 0 2 2 2 1 RNase P subunit p30 ACOX PF01756.19 ORY94375.1 - 1.3e-34 119.3 0.0 2.4e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORY94375.1 - 3.4e-16 59.2 0.1 7.3e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORY94375.1 - 1.8e-14 54.4 0.2 3.9e-14 53.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORY94375.1 - 0.011 15.9 0.1 0.041 14.1 0.1 1.9 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY94375.1 - 0.04 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain DUF469 PF04320.14 ORY94375.1 - 0.16 12.9 0.0 5 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein with unknown function (DUF469) ADH_N PF08240.12 ORY94376.1 - 5.3e-25 87.4 3.6 1e-24 86.5 3.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY94376.1 - 3.6e-18 65.8 0.1 6.2e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY94376.1 - 3.3e-05 23.3 0.0 5.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY94376.1 - 0.0002 20.7 0.5 0.00048 19.5 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORY94376.1 - 0.0012 19.9 0.0 0.002 19.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GFO_IDH_MocA PF01408.22 ORY94376.1 - 0.023 15.5 0.1 0.099 13.5 0.1 2.0 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_25 PF13649.6 ORY94376.1 - 0.13 13.0 0.1 0.28 11.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain MRP-L51 PF10244.9 ORY94377.1 - 0.018 15.3 1.1 0.034 14.3 1.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit tRNA-synt_His PF13393.6 ORY94378.1 - 1.4e-38 132.9 0.0 6.2e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ORY94378.1 - 7.9e-12 45.2 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 ORY94378.1 - 9.7e-09 35.1 0.1 9.7e-09 35.1 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs WHEP-TRS PF00458.20 ORY94378.1 - 3.9e-06 26.9 8.7 1.5e-05 25.1 8.7 2.1 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 ORY94378.1 - 3.8e-05 23.7 0.0 0.00025 21.1 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 ORY94378.1 - 0.00028 20.1 0.2 0.0035 16.5 0.2 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF1820 PF08850.11 ORY94378.1 - 0.1 13.1 0.1 0.33 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) ORF6C PF10552.9 ORY94378.1 - 0.56 10.3 4.2 2.5 8.2 4.2 2.1 1 1 0 1 1 1 0 ORF6C domain F-box-like PF12937.7 ORY94379.1 - 0.00012 21.9 0.2 0.00033 20.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY94379.1 - 0.0055 16.6 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain DNA_gyraseB_C PF00986.21 ORY94379.1 - 0.22 11.7 0.3 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus LRR_4 PF12799.7 ORY94379.1 - 0.26 11.8 4.6 1.2 9.7 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Phage_holin_4_2 PF04020.13 ORY94380.1 - 0.0078 16.9 2.2 0.0078 16.9 2.2 3.0 3 0 0 3 3 3 1 Mycobacterial 4 TMS phage holin, superfamily IV MSP1a PF11670.8 ORY94380.1 - 0.96 8.7 9.2 0.028 13.7 1.5 2.1 3 0 0 3 3 3 0 Major surface protein 1a (MSP1a) RNA_pol_A_bac PF01000.26 ORY94381.1 - 4.6e-34 117.2 0.0 6.1e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORY94381.1 - 6.4e-10 38.3 0.0 7.7e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 ORY94381.1 - 0.09 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 3Beta_HSD PF01073.19 ORY94382.1 - 3.7e-69 232.8 0.0 4.6e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY94382.1 - 8.7e-34 117.0 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY94382.1 - 1.9e-17 63.7 0.0 1.1e-16 61.1 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORY94382.1 - 1.3e-14 54.0 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY94382.1 - 2.6e-12 47.0 0.0 3.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY94382.1 - 9.3e-12 44.6 0.0 7.8e-11 41.6 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY94382.1 - 2.7e-07 30.0 0.1 1.5e-06 27.5 0.0 2.2 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY94382.1 - 0.0019 18.1 0.3 0.14 12.0 0.3 2.7 1 1 0 1 1 1 1 KR domain Glyco_tran_28_C PF04101.16 ORY94383.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ribosomal_L14 PF00238.19 ORY94384.1 - 3.1e-36 124.1 0.2 3.7e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e tRNA-synt_2 PF00152.20 ORY94386.1 - 6.4e-80 268.6 0.1 9.1e-80 268.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY94386.1 - 4.3e-13 49.0 0.0 8.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY94386.1 - 2.1e-09 37.2 0.0 0.00034 20.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ribosomal_60s PF00428.19 ORY94386.1 - 1.1 9.8 11.3 3.4 8.3 11.3 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein NUC153 PF08159.12 ORY94387.1 - 3.3e-15 55.6 16.2 3.7e-14 52.2 1.4 4.2 4 0 0 4 4 4 3 NUC153 domain CRISPR_Cse2 PF09485.10 ORY94387.1 - 0.099 13.2 2.0 4.8 7.7 0.3 2.8 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) ABC_membrane_2 PF06472.15 ORY94388.1 - 1.4e-95 319.8 4.2 1.9e-95 319.3 4.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY94388.1 - 3.7e-17 63.1 0.0 1.7e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 ORY94388.1 - 0.00046 20.6 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ORY94388.1 - 0.0083 15.9 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 ORY94388.1 - 0.0092 16.4 0.6 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY94388.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ORY94388.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 ORY94388.1 - 0.035 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ORY94388.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY94388.1 - 0.1 13.2 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY94388.1 - 0.11 12.2 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 ORY94388.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY94388.1 - 0.13 12.8 0.1 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 ORY94389.1 - 3.1e-18 65.3 0.1 4.5e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 ORY94389.1 - 0.00044 20.4 0.1 0.00071 19.7 0.1 1.3 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 ORY94389.1 - 0.00095 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY94389.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif Ndc1_Nup PF09531.10 ORY94389.1 - 3.9 6.1 6.5 4.3 5.9 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 ORY94390.1 - 1.3e-31 109.8 40.9 1e-16 60.8 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY94390.1 - 4.1e-05 22.6 0.6 4.1e-05 22.6 0.6 2.5 1 1 1 3 3 3 1 MFS_1 like family MFS_3 PF05977.13 ORY94390.1 - 0.093 11.1 9.2 0.019 13.3 5.2 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector AgrB PF04647.15 ORY94390.1 - 1.2 8.5 9.5 9.7 5.5 0.0 4.1 4 1 0 4 4 4 0 Accessory gene regulator B Sec63 PF02889.16 ORY94391.1 - 3.8e-167 553.9 0.0 4.3e-92 307.9 0.1 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORY94391.1 - 1.3e-51 174.8 0.2 1.3e-25 90.2 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 ORY94391.1 - 2.9e-39 133.7 0.0 9.9e-39 132.0 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 ORY94391.1 - 1.2e-25 90.4 0.1 3.5e-13 49.9 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY94391.1 - 3.7e-12 46.6 0.0 2.9e-07 30.8 0.0 4.3 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY94391.1 - 2.1e-09 37.8 0.2 0.002 18.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 ORY94391.1 - 8.4e-08 32.2 0.8 0.043 13.5 0.0 4.0 3 1 1 4 4 4 2 AAA domain PhoH PF02562.16 ORY94391.1 - 0.0011 18.5 0.0 0.096 12.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein Helicase_C_2 PF13307.6 ORY94391.1 - 0.0028 17.8 0.0 0.5 10.5 0.0 3.5 4 0 0 4 4 4 1 Helicase C-terminal domain AAA_7 PF12775.7 ORY94391.1 - 0.11 12.0 0.0 9.9 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region COX7a PF02238.15 ORY94392.1 - 6.6e-18 64.9 0.1 7.5e-18 64.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII PEP-CTERM PF07589.11 ORY94392.1 - 0.31 11.2 1.5 0.46 10.6 1.5 1.3 1 0 0 1 1 1 0 PEP-CTERM motif adh_short PF00106.25 ORY94393.1 - 2.9e-44 150.9 0.7 3.4e-44 150.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY94393.1 - 1.4e-34 119.7 1.8 1.5e-34 119.6 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY94393.1 - 4.7e-12 46.2 1.0 6.3e-12 45.8 1.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY94393.1 - 4.6e-05 22.7 0.1 6.2e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PP2C_2 PF13672.6 ORY94393.1 - 0.00047 19.9 0.1 0.00073 19.2 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C NAD_binding_10 PF13460.6 ORY94393.1 - 0.00073 19.5 3.8 0.0012 18.8 3.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY94393.1 - 0.0049 16.4 0.8 0.075 12.5 0.8 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY94393.1 - 0.012 15.0 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDPD PF03009.17 ORY94394.1 - 2.5e-17 63.5 0.0 6.4e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Aa_trans PF01490.18 ORY94395.1 - 1.2e-81 274.5 30.2 1.5e-81 274.2 30.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_desaturase PF00487.24 ORY94395.1 - 0.0048 16.8 3.2 0.0048 16.8 3.2 3.0 3 0 0 3 3 3 1 Fatty acid desaturase SelP_N PF04592.14 ORY94395.1 - 1.4 8.3 15.1 2.1 7.7 15.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region YpmT PF17431.2 ORY94395.1 - 3.2 7.9 5.3 0.45 10.6 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized YmpT-like zf-CHCC PF10276.9 ORY94396.1 - 1.8e-19 69.5 1.9 2.5e-19 69.0 1.9 1.2 1 0 0 1 1 1 1 Zinc-finger domain STAC2_u1 PF16664.5 ORY94396.1 - 0.084 13.3 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CPSF_A PF03178.15 ORY94397.1 - 4.6e-20 72.2 0.0 1e-19 71.0 0.0 1.5 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 ORY94399.1 - 5.1e-14 51.8 0.0 6.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pkinase PF00069.25 ORY94400.1 - 4.5e-50 170.5 0.0 7.5e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94400.1 - 1.8e-36 125.7 0.0 2.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 ORY94400.1 - 3.4e-05 24.0 0.2 7.5e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain GH114_assoc PF14741.6 ORY94400.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain E2R135 PF11570.8 ORY94400.1 - 0.049 13.9 0.7 0.1 12.9 0.7 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Pkinase_fungal PF17667.1 ORY94400.1 - 0.063 12.0 0.5 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase MutS_IV PF05190.18 ORY94400.1 - 0.21 12.0 1.3 0.38 11.1 0.3 2.0 2 0 0 2 2 2 0 MutS family domain IV Golgin_A5 PF09787.9 ORY94400.1 - 0.21 11.0 2.5 0.32 10.4 2.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 ORY94400.1 - 0.26 10.1 3.1 0.44 9.4 3.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.25 ORY94401.1 - 2.4e-60 204.1 0.1 2.9e-60 203.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94401.1 - 7.5e-27 94.2 0.1 1.8e-26 93.0 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY94401.1 - 0.0063 16.1 0.9 0.0099 15.5 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 ORY94401.1 - 0.0067 15.8 0.5 0.015 14.7 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY94401.1 - 0.0082 15.0 0.2 0.013 14.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY94401.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 ORY94401.1 - 0.024 14.3 0.4 0.6 9.7 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY94401.1 - 0.1 12.5 0.1 1.5 8.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family CRAL_TRIO PF00650.20 ORY94403.1 - 1.3e-39 135.5 0.0 2.2e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY94403.1 - 3.8e-10 39.8 0.1 7.5e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY94403.1 - 1.5e-06 28.4 0.0 2.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ATP-synt_ab PF00006.25 ORY94404.1 - 4.5e-71 238.9 0.0 6.4e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY94404.1 - 1.7e-46 157.6 0.0 2.8e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY94404.1 - 3.6e-20 72.2 0.6 1.2e-19 70.6 0.6 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Cid2 PF09774.9 ORY94405.1 - 2.5e-21 76.8 3.5 1.2e-19 71.3 3.5 2.3 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Ribosomal_S15 PF00312.22 ORY94405.1 - 0.0025 18.0 0.6 0.0052 17.0 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 His_Phos_2 PF00328.22 ORY94405.1 - 0.024 14.0 1.1 0.026 13.9 1.1 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) PRANC PF09372.10 ORY94405.1 - 0.032 14.6 1.6 0.16 12.3 0.5 2.1 2 0 0 2 2 2 0 PRANC domain GatB_Yqey PF02637.18 ORY94405.1 - 0.062 13.2 0.6 1.2 9.0 0.6 2.2 1 1 0 1 1 1 0 GatB domain MitMem_reg PF13012.6 ORY94406.1 - 1.2e-29 103.0 0.6 2.2e-29 102.2 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY94406.1 - 3.2e-12 46.5 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease D5_N PF08706.11 ORY94406.1 - 0.16 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 D5 N terminal like Aa_trans PF01490.18 ORY94407.1 - 4.5e-49 167.2 15.1 5.9e-49 166.9 15.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY94407.1 - 0.0024 17.0 6.4 0.0024 17.0 6.4 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Polysacc_deac_1 PF01522.21 ORY94408.1 - 4.5e-24 84.7 0.3 1.3e-23 83.2 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF4524 PF15025.6 ORY94408.1 - 0.12 12.1 0.5 0.26 11.0 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) DASH_Dad2 PF08654.10 ORY94410.1 - 2.3e-10 40.8 0.1 8.7e-10 38.9 0.0 1.7 1 1 1 2 2 2 1 DASH complex subunit Dad2 Glu-tRNAGln PF02686.15 ORY94410.1 - 0.011 16.0 0.1 0.014 15.6 0.1 1.2 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DNA_primase_S PF01896.19 ORY94410.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.0 1 0 0 1 1 1 0 DNA primase small subunit TFIIB PF00382.19 ORY94411.1 - 3.9e-33 113.3 1.3 4.2e-17 61.9 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 ORY94411.1 - 1.9e-22 79.5 3.8 1.9e-22 79.5 3.8 2.9 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 ORY94411.1 - 1.3e-10 40.6 1.4 3.5e-10 39.2 1.4 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ORY94411.1 - 0.00038 20.2 0.1 0.77 9.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF1279 PF06916.13 ORY94412.1 - 1.6e-15 57.4 0.0 2.9e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) AA_permease PF00324.21 ORY94414.1 - 3.8e-113 378.6 38.1 4.6e-113 378.4 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY94414.1 - 5.3e-36 124.4 37.4 6.5e-36 124.1 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease WTF PF03303.13 ORY94414.1 - 0.05 13.3 8.5 0.026 14.3 5.3 2.0 2 0 0 2 2 2 0 WTF protein PFU PF09070.11 ORY94415.1 - 2.4e-41 140.5 0.1 4e-41 139.8 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 ORY94415.1 - 2.5e-37 126.2 16.0 1.6e-07 31.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.11 ORY94415.1 - 5.9e-29 101.2 0.2 8.3e-29 100.7 0.2 1.2 1 0 0 1 1 1 1 PUL domain PQQ_3 PF13570.6 ORY94415.1 - 0.21 12.1 2.0 2.6 8.6 0.2 3.3 3 1 0 3 3 3 0 PQQ-like domain Cupin_8 PF13621.6 ORY94416.1 - 3.7e-18 66.2 0.1 8.2e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY94416.1 - 9.1e-16 58.3 0.0 2.4e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ANAPC1 PF12859.7 ORY94416.1 - 0.034 14.7 1.5 0.077 13.6 1.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 CotJB PF12652.7 ORY94416.1 - 0.57 10.4 3.0 9.6 6.5 0.5 2.7 2 0 0 2 2 2 0 CotJB protein SR-25 PF10500.9 ORY94416.1 - 1 8.9 32.1 0.032 13.8 21.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 ORY94416.1 - 3.4 6.0 9.9 4.7 5.5 9.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Dsh_C PF12316.8 ORY94416.1 - 9.5 6.6 15.7 1.3 9.4 11.6 1.7 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal VTC PF09359.10 ORY94417.1 - 8.6e-81 271.3 0.4 1.9e-80 270.2 0.0 1.8 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 ORY94417.1 - 1.4e-13 51.1 3.1 1.4e-13 51.1 3.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 ORY94417.1 - 1.3e-06 28.6 21.3 0.00085 19.3 6.7 3.7 2 1 1 3 3 3 2 SPX domain VTC PF09359.10 ORY94418.1 - 7.1e-87 291.3 0.1 1.4e-86 290.3 0.1 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 ORY94418.1 - 4.8e-13 49.8 10.6 1.2e-07 32.0 0.4 3.3 1 1 2 3 3 3 3 SPX domain DUF202 PF02656.15 ORY94418.1 - 0.011 16.1 0.0 0.032 14.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Baculo_PEP_C PF04513.12 ORY94418.1 - 0.22 11.6 0.1 0.37 10.8 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus XAP5 PF04921.14 ORY94420.1 - 7.6e-85 284.7 11.1 7.6e-85 284.7 11.1 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF966 PF06136.13 ORY94420.1 - 0.51 10.0 14.6 0.82 9.3 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MM_CoA_mutase PF01642.22 ORY94420.1 - 3.6 6.0 8.6 2 6.8 6.9 1.3 1 1 0 1 1 1 0 Methylmalonyl-CoA mutase EphA2_TM PF14575.6 ORY94421.1 - 0.019 15.8 0.0 0.041 14.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 ORY94421.1 - 0.066 13.6 0.6 0.13 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DAG1 PF05454.11 ORY94421.1 - 0.068 12.5 0.2 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Med7 PF05983.11 ORY94422.1 - 4.9e-55 186.6 1.4 6.4e-55 186.2 1.4 1.1 1 0 0 1 1 1 1 MED7 protein DUF2019 PF09450.10 ORY94422.1 - 0.019 14.9 0.4 0.03 14.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Ank_2 PF12796.7 ORY94423.1 - 1.2e-12 48.2 0.0 3.4e-09 37.2 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY94423.1 - 6.9e-10 39.0 0.1 8.2e-07 29.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY94423.1 - 1.4e-08 34.3 0.4 0.01 16.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ORY94423.1 - 7.6e-08 32.5 0.4 0.0016 18.8 0.0 3.8 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 ORY94423.1 - 6.5e-07 29.8 0.1 1.1e-05 25.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Lipase_GDSL_2 PF13472.6 ORY94425.1 - 0.013 15.9 0.1 0.029 14.8 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Propeptide_C1 PF08127.13 ORY94425.1 - 0.084 12.8 0.2 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C1 propeptide Fasciclin PF02469.22 ORY94426.1 - 1.4e-11 44.8 1.6 3.9e-09 36.8 0.3 2.9 2 1 0 2 2 2 2 Fasciclin domain Clat_adaptor_s PF01217.20 ORY94427.1 - 2e-33 115.3 0.1 2.3e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AA_permease PF00324.21 ORY94428.1 - 2.3e-30 105.6 5.6 2.7e-30 105.4 5.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY94428.1 - 2.9e-07 29.7 4.5 3.5e-07 29.4 4.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY94429.1 - 3.5e-87 293.0 24.3 4e-87 292.8 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY94429.1 - 3e-34 118.6 27.4 3.5e-34 118.4 27.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.8 ORY94429.1 - 0.4 10.7 0.0 0.4 10.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) FixP_N PF14715.6 ORY94429.1 - 2.9 7.7 6.9 8.8 6.2 1.4 3.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP UQ_con PF00179.26 ORY94430.1 - 6e-32 110.2 0.1 7e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY94430.1 - 0.022 15.1 0.1 0.027 14.7 0.1 1.3 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 ORY94430.1 - 0.036 13.7 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Zn_clus PF00172.18 ORY94431.1 - 4.2e-05 23.6 9.9 0.00011 22.2 9.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY94431.1 - 0.0044 16.1 0.1 0.0088 15.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain KTI12 PF08433.10 ORY94431.1 - 0.065 12.7 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Foie-gras_1 PF11817.8 ORY94431.1 - 0.087 12.4 0.4 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 Foie gras liver health family 1 ThiF PF00899.21 ORY94432.1 - 4.6e-25 88.4 0.0 8.7e-25 87.5 0.0 1.5 1 1 0 1 1 1 1 ThiF family P4Ha_N PF08336.11 ORY94432.1 - 0.043 13.8 1.2 0.62 10.1 0.1 2.6 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Rv2175c_C PF18367.1 ORY94432.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 Rv2175c C-terminal domain of unknown function Methyltransf_3 PF01596.17 ORY94433.1 - 9.8e-42 142.5 0.0 1.2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORY94433.1 - 2.4e-13 51.0 0.1 6e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY94433.1 - 1.8e-06 27.8 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 ORY94433.1 - 6e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY94433.1 - 0.00011 22.8 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY94433.1 - 0.0012 18.6 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 ORY94433.1 - 0.0071 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY94433.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PigN PF04987.14 ORY94434.1 - 7.7e-131 437.1 37.0 1e-130 436.7 37.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 ORY94434.1 - 7.6e-16 58.6 0.1 8.3e-14 51.9 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY94434.1 - 3.1e-06 26.8 0.1 6.4e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 ORY94434.1 - 0.0047 16.3 0.1 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1129 PF06570.11 ORY94434.1 - 1.5 8.3 4.8 2.1 7.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) MASE2 PF05230.11 ORY94434.1 - 3.6 7.7 14.2 1 9.5 1.9 3.5 3 0 0 3 3 3 0 MASE2 domain DUF5528 PF17666.1 ORY94435.1 - 0.00071 19.5 0.9 0.00082 19.3 0.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5528) Med30 PF11315.8 ORY94435.1 - 0.0019 18.4 1.5 0.0026 18.0 1.5 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 RNase_H2-Ydr279 PF09468.10 ORY94435.1 - 0.079 13.1 1.5 0.089 13.0 1.5 1.3 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF4510 PF14971.6 ORY94435.1 - 0.1 13.0 2.8 0.15 12.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Prp18 PF02840.15 ORY94435.1 - 0.23 11.5 2.3 0.29 11.2 0.3 1.9 1 1 1 2 2 2 0 Prp18 domain Fib_alpha PF08702.10 ORY94435.1 - 0.23 11.6 2.3 0.23 11.6 1.3 1.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2379 PF09543.10 ORY94435.1 - 0.3 11.3 7.2 0.52 10.5 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2379) DASH_Dam1 PF08653.10 ORY94435.1 - 0.38 10.6 2.1 2.1 8.2 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 FUSC PF04632.12 ORY94435.1 - 0.6 8.6 9.1 0.68 8.4 9.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YlqD PF11068.8 ORY94435.1 - 0.78 10.1 4.6 0.9 9.9 3.7 1.6 1 1 0 1 1 1 0 YlqD protein APG6_N PF17675.1 ORY94435.1 - 0.83 10.2 9.5 1.7 9.2 1.0 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 ORY94435.1 - 0.87 10.1 6.5 0.59 10.6 3.8 1.9 1 1 1 2 2 2 0 Cell division protein ZapB HbrB PF08539.11 ORY94436.1 - 2.4e-36 125.3 0.2 2.4e-36 125.3 0.2 3.4 3 1 0 3 3 3 1 HbrB-like Cullin PF00888.22 ORY94436.1 - 0.0013 17.5 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family SRF-TF PF00319.18 ORY94437.1 - 1.4e-21 75.7 0.1 1.9e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Velvet PF11754.8 ORY94439.1 - 8.5e-38 130.7 2.4 1.9e-32 113.2 0.2 3.6 2 2 1 3 3 3 2 Velvet factor FAM176 PF14851.6 ORY94439.1 - 0.0079 15.9 2.8 0.011 15.3 1.0 2.0 2 0 0 2 2 2 1 FAM176 family PRIMA1 PF16101.5 ORY94439.1 - 3.1 7.9 7.3 0.73 9.9 3.7 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RskA PF10099.9 ORY94439.1 - 7 6.9 15.7 3.1 8.1 4.1 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA NuA4 PF09340.10 ORY94440.1 - 1.5e-22 79.3 1.1 1.5e-22 79.3 1.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 NAD_binding_4 PF07993.12 ORY94441.1 - 1.6e-44 152.1 0.0 2.7e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 ORY94441.1 - 3.7e-10 39.5 0.0 1.2e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase Epimerase PF01370.21 ORY94441.1 - 0.00025 20.6 0.1 0.00073 19.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sterile PF03015.19 ORY94441.1 - 0.17 12.1 0.9 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein SH3_9 PF14604.6 ORY94442.1 - 6e-29 99.6 0.6 1.3e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 ORY94442.1 - 1.3e-26 92.6 0.0 2.9e-16 59.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SH3_1 PF00018.28 ORY94442.1 - 3.3e-25 87.5 2.6 1.7e-12 46.8 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 ORY94442.1 - 2.2e-16 59.3 0.0 4.4e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 ORY94442.1 - 1.6e-08 34.1 0.3 3.7e-08 32.9 0.3 1.7 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.32 ORY94442.1 - 0.013 15.0 0.1 0.044 13.3 0.1 2.0 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 ORY94442.1 - 0.064 13.7 0.0 0.55 10.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair Metallophos PF00149.28 ORY94443.1 - 9.4e-17 62.2 0.5 1.5e-16 61.6 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 ORY94443.1 - 7.9e-11 42.4 0.0 1.8e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 ORY94443.1 - 1.7e-05 25.6 0.1 6.5e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C DUF4609 PF15382.6 ORY94443.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) HARE-HTH PF05066.13 ORY94444.1 - 0.00032 21.0 0.0 0.00071 19.9 0.0 1.5 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain SUIM_assoc PF16619.5 ORY94444.1 - 0.0046 17.0 3.6 0.0046 17.0 3.6 5.8 4 1 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 KilA-N PF04383.13 ORY94444.1 - 0.06 13.2 0.0 1.2 9.0 0.0 3.0 3 1 0 3 3 3 0 KilA-N domain GATA PF00320.27 ORY94445.1 - 2.1e-11 43.2 7.0 3.3e-11 42.6 7.0 1.3 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 ORY94445.1 - 0.015 15.2 1.1 0.027 14.4 1.1 1.5 1 0 0 1 1 1 0 Nudix N-terminal zf-ribbon_3 PF13248.6 ORY94445.1 - 0.18 11.3 2.8 0.42 10.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 ORY94445.1 - 0.88 9.1 5.3 0.57 9.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-ribbon Ctf8 PF09696.10 ORY94446.1 - 2.3e-10 41.0 0.2 3e-06 27.6 0.1 3.0 1 1 1 2 2 2 2 Ctf8 WD40 PF00400.32 ORY94447.1 - 9.6e-31 105.4 22.8 9.8e-08 32.6 1.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY94447.1 - 1.6e-11 44.3 0.6 3.8e-06 27.1 0.1 5.1 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY94447.1 - 0.00011 21.0 2.5 2.9 6.4 0.1 4.1 3 1 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY94447.1 - 0.0021 18.0 0.0 0.01 15.7 0.0 2.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY94447.1 - 0.0032 16.9 0.0 0.032 13.6 0.0 2.3 3 0 0 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 ORY94447.1 - 0.011 14.5 1.2 0.6 8.8 0.3 2.7 2 1 0 3 3 3 0 Nup133 N terminal like Ge1_WD40 PF16529.5 ORY94447.1 - 0.028 13.4 3.4 3.2 6.6 0.4 3.9 1 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PHTB1_N PF14727.6 ORY94447.1 - 0.099 12.0 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 PTHB1 N-terminus PSP1 PF04468.12 ORY94448.1 - 2.4e-32 111.0 1.5 2.4e-32 111.0 1.5 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region SUIM_assoc PF16619.5 ORY94448.1 - 0.01 15.8 1.3 0.01 15.8 1.3 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LIME1 PF15332.6 ORY94448.1 - 0.082 12.5 2.4 0.11 12.1 2.4 1.1 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 OrfB_Zn_ribbon PF07282.11 ORY94451.1 - 6.2e-05 22.8 0.0 7.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY94452.1 - 0.003 17.5 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PLU-1 PF08429.11 ORY94454.1 - 6.9e-51 173.4 1.1 6.9e-51 173.4 1.1 2.0 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 ORY94454.1 - 3.2e-41 140.3 0.7 3.2e-41 140.3 0.7 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.29 ORY94454.1 - 4.6e-28 96.9 44.3 1.7e-11 43.8 7.3 4.5 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 ORY94454.1 - 1e-21 77.4 0.1 3e-21 75.9 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 ORY94454.1 - 2.1e-16 59.6 1.1 5.3e-16 58.3 1.1 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 ORY94454.1 - 3e-12 46.7 14.1 3e-12 46.7 14.1 3.5 4 0 0 4 4 3 1 C5HC2 zinc finger CCDC106 PF15794.5 ORY94454.1 - 8.7e-05 22.3 0.4 0.00037 20.3 0.4 2.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 MADF_DNA_bdg PF10545.9 ORY94454.1 - 0.008 16.5 1.5 7.6 6.9 0.3 3.3 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like C1_1 PF00130.22 ORY94454.1 - 0.0086 15.9 0.7 0.0086 15.9 0.7 4.9 4 0 0 4 4 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 ORY94454.1 - 0.035 14.4 0.4 0.035 14.4 0.4 4.3 3 0 0 3 3 3 0 RING-H2 zinc finger domain EHD_N PF16880.5 ORY94454.1 - 1.2 9.1 3.5 6.3 6.8 0.1 2.8 3 0 0 3 3 3 0 N-terminal EH-domain containing protein SPRY PF00622.28 ORY94455.1 - 3.8e-07 30.3 0.1 3.7e-06 27.0 0.0 2.6 3 0 0 3 3 3 1 SPRY domain DUF4326 PF14216.6 ORY94455.1 - 0.073 13.8 0.0 0.29 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) SUIM_assoc PF16619.5 ORY94456.1 - 0.25 11.5 21.3 2.3 8.3 5.7 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Rho_Binding PF08912.11 ORY94456.1 - 0.26 12.1 10.0 0.11 13.4 3.7 2.3 2 0 0 2 2 2 0 Rho Binding VIT1 PF01988.19 ORY94456.1 - 1.4 8.8 2.7 2.1 8.2 2.7 1.3 1 0 0 1 1 1 0 VIT family DUF4834 PF16118.5 ORY94456.1 - 1.8 9.5 4.5 7.7 7.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) YebO PF13974.6 ORY94456.1 - 9.2 6.4 13.1 1.6 8.9 7.2 2.2 2 0 0 2 2 2 0 YebO-like protein BCDHK_Adom3 PF10436.9 ORY94457.1 - 3.5e-39 134.3 0.0 5.5e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY94457.1 - 3.5e-11 43.6 0.0 6.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RXT2_N PF08595.11 ORY94458.1 - 0.55 10.2 10.2 12 5.9 0.1 2.1 1 1 1 2 2 2 0 RXT2-like, N-terminal DUF3395 PF11875.8 ORY94459.1 - 5.6e-44 149.8 0.3 5.6e-44 149.8 0.3 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 ORY94459.1 - 9.8e-21 73.7 1.1 9.8e-21 73.7 1.1 2.2 2 0 0 2 2 2 1 DnaJ domain FlgN PF05130.12 ORY94459.1 - 0.0048 17.4 0.0 0.0048 17.4 0.0 2.5 4 0 0 4 4 4 1 FlgN protein TraE PF05309.11 ORY94459.1 - 0.052 12.9 0.4 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 TraE protein DNA_pol3_a_NII PF11490.8 ORY94459.1 - 4.2 7.3 8.6 0.19 11.6 1.2 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Chitin_synth_2 PF03142.15 ORY94460.1 - 9.4e-238 790.1 2.0 1.4e-237 789.5 2.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY94460.1 - 1.3e-13 51.4 0.0 2.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY94460.1 - 2.4e-12 47.2 2.7 2.4e-12 47.2 2.7 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY94460.1 - 8.4e-05 22.1 0.3 0.00027 20.5 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY94460.1 - 0.18 11.6 0.0 0.77 9.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 RTC4 PF14474.6 ORY94460.1 - 0.2 11.8 0.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 RTC4-like domain DUF3337 PF11816.8 ORY94461.1 - 1.1e-42 145.8 0.0 3e-42 144.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 ORY94461.1 - 6.7e-23 80.5 24.8 4.3e-06 27.4 1.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY94461.1 - 0.00011 22.4 1.7 0.3 11.4 0.1 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY94461.1 - 0.028 13.8 0.0 0.84 8.9 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain BTB PF00651.31 ORY94462.1 - 0.00014 22.0 0.0 0.00079 19.6 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Telomere_reg-2 PF10193.9 ORY94462.1 - 0.016 15.6 0.2 0.094 13.2 0.0 2.4 2 0 0 2 2 2 0 Telomere length regulation protein OST3_OST6 PF04756.13 ORY94463.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family GPI-anchored PF10342.9 ORY94464.1 - 9.4e-12 45.5 0.6 1.8e-11 44.6 0.6 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3304 PF11745.8 ORY94464.1 - 0.12 12.8 0.3 0.3 11.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) BAG PF02179.16 ORY94465.1 - 3.5e-10 40.2 0.4 3.5e-10 40.2 0.4 2.8 2 1 0 2 2 2 1 BAG domain FliG_N PF14842.6 ORY94465.1 - 0.057 14.0 6.5 0.067 13.7 3.1 2.5 2 0 0 2 2 2 0 FliG N-terminal domain NOA36 PF06524.12 ORY94465.1 - 2.5 7.4 19.6 5.4 6.2 19.6 1.6 1 0 0 1 1 1 0 NOA36 protein UPF0047 PF01894.17 ORY94466.1 - 2e-37 127.8 0.0 2.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PP2C PF00481.21 ORY94467.1 - 6.9e-81 271.7 0.0 1.2e-80 270.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C dCMP_cyt_deam_1 PF00383.23 ORY94468.1 - 3.2e-24 84.7 0.2 4.4e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY94468.1 - 1.4e-20 73.5 0.0 1.5e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORY94468.1 - 0.0018 18.3 0.5 0.008 16.3 0.5 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 ORY94468.1 - 0.0022 18.1 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 ORY94468.1 - 0.0044 17.1 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 ORY94468.1 - 0.034 14.1 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 ORY94468.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 APOBEC1 APOBEC2 PF18772.1 ORY94468.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 F-box PF00646.33 ORY94469.1 - 0.0039 17.0 0.3 0.008 16.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY94469.1 - 0.0067 16.3 0.4 0.016 15.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like XS PF03468.14 ORY94469.1 - 0.035 14.4 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 XS domain Elongin_A PF06881.11 ORY94469.1 - 0.1 13.1 1.0 0.23 12.0 0.0 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-H2C2 PF09337.10 ORY94469.1 - 0.17 12.1 0.9 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 H2C2 zinc finger GATA PF00320.27 ORY94471.1 - 2.1e-15 56.0 4.6 3.7e-15 55.2 4.6 1.4 1 0 0 1 1 1 1 GATA zinc finger HlyD_D23 PF16576.5 ORY94471.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TF_Zn_Ribbon PF08271.12 ORY94471.1 - 0.04 13.4 3.3 0.097 12.2 0.5 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 ORY94471.1 - 0.071 13.3 0.6 0.071 13.3 0.6 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 ORY94471.1 - 0.087 13.0 1.1 1 9.5 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 ORY94471.1 - 0.1 12.5 1.6 17 5.4 0.6 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Apocytochr_F_N PF16639.5 ORY94471.1 - 0.11 12.7 2.0 0.24 11.7 0.1 2.3 1 1 1 2 2 2 0 Apocytochrome F, N-terminal zf-RRN7 PF11781.8 ORY94471.1 - 1.5 8.6 5.7 0.1 12.3 0.5 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 ORY94471.1 - 2.5 8.2 6.4 6.2 6.9 2.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon BPL_N PF09825.9 ORY94472.1 - 7.9e-108 360.9 0.1 3.6e-107 358.7 0.1 1.7 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 ORY94472.1 - 5.4e-23 81.3 0.0 9.1e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 ORY94472.1 - 4.3e-05 23.3 0.0 9.9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain GATase_3 PF07685.14 ORY94472.1 - 0.0051 16.4 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 ORY94472.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Recep_L_domain PF01030.24 ORY94473.1 - 1.9e-10 40.8 2.0 0.0067 16.5 0.0 5.3 2 2 1 4 4 4 4 Receptor L domain S6OS1 PF15676.5 ORY94473.1 - 0.22 9.9 0.2 0.31 9.5 0.2 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Ecm33 PF12454.8 ORY94473.1 - 0.6 10.3 3.4 0.69 10.1 0.1 2.7 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein Arv1 PF04161.13 ORY94474.1 - 4e-61 206.8 11.8 4.5e-61 206.7 11.8 1.0 1 0 0 1 1 1 1 Arv1-like family Kelch_4 PF13418.6 ORY94475.1 - 7.4e-19 67.5 1.9 2.1e-06 27.7 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY94475.1 - 2.5e-15 55.8 3.7 0.00077 19.0 0.2 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 ORY94475.1 - 5.4e-15 55.1 1.1 0.0056 16.9 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 ORY94475.1 - 1.1e-10 41.3 0.1 0.0021 18.0 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 ORY94475.1 - 1.9e-10 40.8 0.9 0.0013 19.0 0.0 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY94475.1 - 6.3e-10 38.6 0.6 0.011 15.7 0.1 5.6 5 0 0 5 5 5 2 Kelch motif F-box PF00646.33 ORY94475.1 - 1.3e-06 28.2 0.1 2.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY94475.1 - 0.0014 18.5 0.2 0.003 17.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like TFIIA PF03153.13 ORY94475.1 - 0.04 13.9 5.9 0.052 13.5 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box_4 PF15966.5 ORY94475.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box AIP3 PF03915.13 ORY94478.1 - 2.1e-64 218.1 28.6 1.5e-63 215.3 24.4 2.6 2 1 0 2 2 2 1 Actin interacting protein 3 Spc7 PF08317.11 ORY94478.1 - 0.0049 15.8 11.8 0.0049 15.8 11.8 2.6 2 1 1 3 3 3 1 Spc7 kinetochore protein Mce4_CUP1 PF11887.8 ORY94478.1 - 0.1 12.1 2.2 0.21 11.0 2.0 1.6 1 1 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Phage_Mu_Gam PF07352.12 ORY94478.1 - 0.22 11.4 0.1 0.22 11.4 0.1 3.5 4 1 0 4 4 4 0 Bacteriophage Mu Gam like protein DUF1664 PF07889.12 ORY94478.1 - 1.9 8.5 16.8 0.97 9.5 1.5 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 ORY94478.1 - 7.3 5.9 24.2 0.047 13.0 10.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 ORY94478.1 - 8.6 6.7 9.7 3.5 8.0 0.8 4.1 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) UCR_hinge PF02320.16 ORY94478.1 - 10 6.4 9.4 1.4 9.2 4.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein SH3_1 PF00018.28 ORY94479.1 - 9.5e-07 28.3 0.1 1.9e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY94479.1 - 9.2e-06 25.2 0.0 2.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY94479.1 - 1.2e-05 25.0 0.1 3.5e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain CSN7a_helixI PF18392.1 ORY94479.1 - 0.004 17.0 1.4 0.017 15.0 0.2 2.6 2 0 0 2 2 2 1 COP9 signalosome complex subunit 7a helix I domain FCH PF00611.23 ORY94479.1 - 0.03 14.6 7.7 0.026 14.8 4.1 3.0 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain zf-RING_2 PF13639.6 ORY94480.1 - 8.4e-13 48.4 5.2 1.2e-12 47.9 5.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY94480.1 - 1.4e-09 37.6 5.9 2.2e-09 37.0 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY94480.1 - 1.8e-09 37.7 3.7 3.2e-09 36.9 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY94480.1 - 9e-08 31.9 3.5 1.4e-07 31.3 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY94480.1 - 1.1e-07 31.8 1.7 1.2e-07 31.6 0.9 1.5 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY94480.1 - 9.8e-07 28.5 3.5 2e-06 27.6 3.6 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ORY94480.1 - 1.1e-06 28.3 5.3 1.8e-06 27.7 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY94480.1 - 1.1e-05 25.1 0.5 1.1e-05 25.1 0.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_10 PF16685.5 ORY94480.1 - 0.00016 21.7 3.6 0.00024 21.2 3.6 1.2 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 ORY94480.1 - 0.0016 18.4 4.0 0.0026 17.7 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY94480.1 - 0.0068 16.4 3.8 0.032 14.3 3.8 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 ORY94480.1 - 0.025 14.7 2.0 0.055 13.6 2.0 1.6 1 1 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 ORY94480.1 - 0.045 13.4 3.9 0.2 11.3 1.4 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-Nse PF11789.8 ORY94480.1 - 0.11 12.3 1.8 0.2 11.5 1.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 ORY94480.1 - 0.12 12.6 0.0 0.81 9.9 0.0 2.0 2 0 0 2 2 2 0 U-box domain FANCL_C PF11793.8 ORY94480.1 - 0.17 12.1 3.5 4.2 7.6 3.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 ORY94480.1 - 0.22 11.3 3.8 0.58 10.0 3.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY94480.1 - 0.3 11.3 4.8 0.68 10.1 4.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 ORY94480.1 - 0.35 10.5 3.3 0.57 9.8 2.8 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RVT PF13966.6 ORY94480.1 - 0.48 11.2 4.2 8.1 7.2 0.2 2.5 3 0 0 3 3 2 0 zinc-binding in reverse transcriptase UPF0547 PF10571.9 ORY94480.1 - 0.6 10.2 3.4 17 5.6 0.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ABA_GPCR PF12430.8 ORY94481.1 - 0.04 13.7 0.2 0.04 13.7 0.2 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor TPT PF03151.16 ORY94482.1 - 2.6e-29 102.5 23.0 3.1e-29 102.2 23.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY94482.1 - 2e-12 47.5 37.3 6.9e-08 32.7 11.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY94482.1 - 6.6e-10 38.7 25.9 9.9e-10 38.1 25.9 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 ORY94482.1 - 0.05 12.8 21.0 0.99 8.5 18.6 2.8 1 1 1 2 2 2 0 Nucleotide-sugar transporter Not1 PF04054.15 ORY94483.1 - 4.6e-116 387.7 0.6 1e-115 386.6 0.2 1.8 1 1 1 2 2 2 1 CCR4-Not complex component, Not1 Ribosomal_S21 PF01165.20 ORY94484.1 - 9.9e-13 47.6 2.4 1.6e-12 47.0 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 WD40 PF00400.32 ORY94486.1 - 3.2e-08 34.1 9.3 0.037 14.9 0.0 5.0 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY94486.1 - 9.1e-06 25.9 0.0 0.072 13.4 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY94486.1 - 0.051 12.5 0.2 4 6.3 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 ORY94486.1 - 0.077 11.0 0.0 0.097 10.6 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Utp11 PF03998.13 ORY94487.1 - 1.3e-71 241.4 31.1 1.5e-71 241.2 31.1 1.0 1 0 0 1 1 1 1 Utp11 protein Bravo_FIGEY PF13882.6 ORY94487.1 - 0.062 14.7 1.8 0.062 14.7 1.8 2.7 1 1 1 2 2 2 0 Bravo-like intracellular region Recep_L_domain PF01030.24 ORY94488.1 - 2.6e-11 43.6 1.3 0.0045 17.1 0.0 4.3 2 1 1 4 4 4 4 Receptor L domain LRR_9 PF14580.6 ORY94488.1 - 0.019 14.4 0.3 0.071 12.6 0.1 2.1 2 1 0 2 2 2 0 Leucine-rich repeat LRR_4 PF12799.7 ORY94488.1 - 0.023 15.1 11.1 0.081 13.4 0.2 4.8 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Ecm33 PF12454.8 ORY94488.1 - 0.084 13.0 0.6 0.084 13.0 0.6 3.1 4 0 0 4 4 4 0 GPI-anchored cell wall organization protein Ribosomal_L10 PF00466.20 ORY94489.1 - 8e-07 29.1 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 4F5 PF04419.14 ORY94490.1 - 1.5e-09 38.5 17.0 1.5e-09 38.5 17.0 2.1 2 0 0 2 2 2 1 4F5 protein family PX PF00787.24 ORY94491.1 - 0.00032 20.7 0.4 0.00062 19.7 0.3 1.7 1 1 0 1 1 1 1 PX domain Ras PF00071.22 ORY94492.1 - 5.7e-57 191.8 0.1 6.6e-57 191.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY94492.1 - 1.1e-31 109.5 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY94492.1 - 1e-11 44.6 0.0 1.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY94492.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY94492.1 - 3.6e-05 23.3 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY94492.1 - 6.6e-05 22.5 0.0 0.0035 16.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY94492.1 - 0.00011 22.2 0.2 0.0037 17.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 ORY94492.1 - 0.0027 17.4 0.2 0.13 12.0 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ORY94492.1 - 0.0035 16.9 0.0 0.0094 15.6 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ORY94492.1 - 0.0057 17.0 0.0 0.0094 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY94492.1 - 0.0082 16.4 0.0 0.018 15.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORY94492.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NTPase Septin PF00735.18 ORY94492.1 - 0.014 14.7 0.1 0.042 13.1 0.1 1.8 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 ORY94492.1 - 0.018 14.5 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 ORY94492.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORY94492.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 ORY94492.1 - 0.037 13.5 0.1 0.064 12.7 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 ORY94492.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 ORY94492.1 - 0.059 12.8 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 ORY94492.1 - 0.083 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 ORY94492.1 - 0.096 11.9 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 ORY94492.1 - 0.12 12.1 0.3 3.8 7.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 ORY94492.1 - 0.17 11.0 0.2 0.34 10.0 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 HSF_DNA-bind PF00447.17 ORY94494.1 - 7.7e-26 90.5 1.1 1e-25 90.2 1.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 ORY94494.1 - 0.086 13.3 0.1 0.22 12.0 0.1 1.8 1 1 0 1 1 1 0 Ets-domain TolA_bind_tri PF16331.5 ORY94494.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation MFS_1 PF07690.16 ORY94496.1 - 1.2e-44 152.7 53.8 9e-35 120.2 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 ORY94496.1 - 8.1 6.7 9.3 1.9 8.8 0.3 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) cwf18 PF08315.12 ORY94497.1 - 6e-36 124.1 14.7 8.5e-36 123.6 14.7 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SIR4_SID PF16991.5 ORY94497.1 - 0.074 13.1 1.9 0.1 12.6 1.9 1.2 1 0 0 1 1 1 0 Sir4 SID domain Thioredox_DsbH PF03190.15 ORY94498.1 - 4.7e-76 254.3 0.0 7.9e-76 253.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 ORY94498.1 - 1.3e-11 44.5 0.0 4.7e-11 42.7 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_127 PF07944.12 ORY94498.1 - 0.00025 19.7 0.2 0.0032 16.0 0.0 2.2 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 ORY94498.1 - 0.00046 19.7 1.6 0.045 13.3 0.1 2.9 3 1 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 ORY94498.1 - 0.00084 18.5 1.2 0.44 9.6 0.1 3.1 3 2 0 3 3 3 2 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.6 ORY94498.1 - 0.078 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Peptidase_S10 PF00450.22 ORY94499.1 - 8e-129 430.7 0.0 9.2e-129 430.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase TRAPP PF04051.16 ORY94500.1 - 4.5e-38 130.3 0.0 5.7e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.10 ORY94500.1 - 0.048 13.9 0.0 6.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) POLO_box PF00659.18 ORY94501.1 - 6.3e-11 42.3 0.1 7.2e-07 29.3 0.1 2.8 2 1 0 2 2 2 2 POLO box duplicated region Pkinase PF00069.25 ORY94502.1 - 2.9e-75 253.0 0.0 3.3e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94502.1 - 9.4e-38 130.0 0.0 1.2e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY94502.1 - 4.9e-06 26.1 0.0 6.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY94502.1 - 0.00033 19.5 0.0 0.00048 19.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 ORY94502.1 - 0.00065 19.3 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 ORY94502.1 - 0.01 15.2 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family E2F_TDP PF02319.20 ORY94503.1 - 7.6e-23 80.4 0.2 2.2e-22 78.9 0.1 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Borrelia_lipo_1 PF05714.11 ORY94503.1 - 0.019 14.8 0.3 0.047 13.5 0.3 1.6 1 1 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein ORC5_C PF14630.6 ORY94503.1 - 1.4 8.4 4.2 33 3.9 4.3 2.5 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus CBS PF00571.28 ORY94505.1 - 2.1e-28 98.5 3.6 2.3e-08 34.3 0.0 4.8 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 ORY94505.1 - 1.4e-07 31.4 0.2 3.5e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 PB1 domain Exo70 PF03081.15 ORY94505.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Pneumo_NS1 PF03438.13 ORY94505.1 - 0.13 12.4 0.0 5.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Pneumovirus NS1 protein PPR_2 PF13041.6 ORY94506.1 - 7.9e-52 173.3 31.7 2.9e-07 30.6 0.0 14.5 10 4 7 17 17 17 12 PPR repeat family PPR_3 PF13812.6 ORY94506.1 - 7.7e-35 118.8 18.6 4e-06 26.8 0.1 12.1 10 1 1 12 12 12 7 Pentatricopeptide repeat domain PPR PF01535.20 ORY94506.1 - 1.1e-34 116.2 36.3 0.00014 21.9 0.0 16.5 17 0 0 17 17 17 10 PPR repeat PPR_long PF17177.4 ORY94506.1 - 1.3e-28 99.8 29.0 1.8e-11 43.8 1.5 7.3 2 2 4 7 7 7 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY94506.1 - 9.3e-26 89.2 19.7 0.00069 19.3 0.0 13.3 14 1 0 14 14 13 7 PPR repeat TPR_14 PF13428.6 ORY94506.1 - 4e-08 33.4 8.2 1.1 10.3 0.2 9.7 9 2 1 10 10 9 1 Tetratricopeptide repeat RPM2 PF08579.11 ORY94506.1 - 2.5e-07 31.1 1.2 0.002 18.5 0.0 5.1 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 ORY94506.1 - 5.8e-06 26.1 2.5 31 4.5 0.0 7.2 6 2 1 7 7 7 0 Mitochondrial ATPase expression TPR_19 PF14559.6 ORY94506.1 - 4.4e-05 23.9 15.4 0.93 10.1 4.4 6.0 4 3 2 7 7 6 3 Tetratricopeptide repeat DUF3368 PF11848.8 ORY94506.1 - 0.0018 18.0 0.1 5.2 6.9 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3368) TPR_16 PF13432.6 ORY94506.1 - 0.0061 17.2 16.2 2.2 9.0 0.3 7.1 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY94506.1 - 0.0064 17.0 0.7 77 4.4 0.6 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY94506.1 - 0.13 12.2 5.1 1.3 9.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ORY94506.1 - 5.2 6.9 15.9 30 4.5 0.0 6.3 5 2 2 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal RhoGAP PF00620.27 ORY94507.1 - 6.1e-38 130.0 0.2 8.3e-37 126.4 0.2 2.2 1 1 0 1 1 1 1 RhoGAP domain DM4_12 PF07841.13 ORY94507.1 - 0.032 14.9 0.0 0.067 13.9 0.0 1.5 1 0 0 1 1 1 0 DM4/DM12 family CAP_N PF01213.19 ORY94507.1 - 0.076 12.5 3.7 0.31 10.5 0.2 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sec23_trunk PF04811.15 ORY94509.1 - 8.1e-61 205.7 0.0 1.5e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY94509.1 - 2.3e-23 81.9 0.4 4.8e-23 80.9 0.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY94509.1 - 2e-17 63.7 0.0 4.2e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY94509.1 - 1.4e-16 60.2 4.9 3.1e-16 59.1 4.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY94509.1 - 8.2e-05 22.4 0.0 0.0024 17.7 0.0 2.8 2 0 0 2 2 2 1 Gelsolin repeat Sugar_tr PF00083.24 ORY94510.1 - 2.6e-108 362.8 16.8 5.6e-108 361.7 16.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY94510.1 - 7.8e-20 71.1 26.8 1.6e-19 70.1 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY94510.1 - 0.00019 20.0 5.8 0.0031 16.0 1.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) RSN1_TM PF13967.6 ORY94510.1 - 0.29 10.9 3.6 0.091 12.5 0.4 1.8 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport tRNA-synt_1b PF00579.25 ORY94511.1 - 9.7e-59 199.1 0.0 1.1e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Trypsin PF00089.26 ORY94512.1 - 9e-23 81.2 0.0 1.3e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY94512.1 - 3.7e-06 27.9 0.0 5.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Rtf2 PF04641.12 ORY94513.1 - 2.1e-79 266.6 9.9 2.6e-79 266.3 9.9 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 ORY94513.1 - 0.0006 19.9 0.0 0.0006 19.9 0.0 2.2 3 0 0 3 3 3 1 Zinc-finger of nitric oxide synthase-interacting protein Prok-RING_1 PF14446.6 ORY94513.1 - 0.14 12.1 1.9 1 9.3 0.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 ORY94513.1 - 1.4 9.0 7.0 1.1 9.3 1.7 2.6 2 0 0 2 2 2 0 RING-type zinc-finger GATA PF00320.27 ORY94514.1 - 7.5e-14 51.0 4.9 2.3e-13 49.5 4.9 1.9 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 ORY94514.1 - 0.02 14.9 1.5 0.066 13.3 1.5 1.9 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ORY94514.1 - 0.067 13.1 2.3 0.24 11.4 2.3 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3336 PF11815.8 ORY94515.1 - 6.5e-17 61.5 0.0 5.3e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY94515.1 - 1.7e-16 61.0 0.0 3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3020 PF11223.8 ORY94516.1 - 3e-20 72.4 12.1 3e-20 72.4 12.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) AAA_23 PF13476.6 ORY94516.1 - 10 6.6 26.6 0.47 10.9 15.8 2.6 2 0 0 2 2 2 0 AAA domain RdRP PF05183.12 ORY94518.1 - 1.3e-92 311.4 0.1 1.7e-92 311.0 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase p450 PF00067.22 ORY94519.1 - 2.4e-94 316.7 0.0 3.4e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORY94519.1 - 9.4e-39 133.3 0.0 2.2e-37 128.8 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY94519.1 - 3.2e-24 85.8 1.2 4.3e-24 85.4 0.2 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ORY94519.1 - 1.7e-17 64.0 0.0 3.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY94519.1 - 0.016 15.3 0.0 0.88 9.7 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain ABC_ATPase PF09818.9 ORY94520.1 - 2.1e-162 541.0 0.0 2.5e-162 540.8 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 ORY94520.1 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY94520.1 - 0.17 11.6 0.3 0.53 10.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_D PF01813.17 ORY94521.1 - 1.7e-73 246.7 5.9 2.1e-73 246.3 5.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SIR2 PF02146.17 ORY94521.1 - 0.00027 20.9 0.1 0.00079 19.4 0.0 1.7 1 1 0 1 1 1 1 Sir2 family TACC_C PF05010.14 ORY94521.1 - 0.0016 18.3 10.3 0.044 13.6 1.5 2.2 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mig-14 PF07395.11 ORY94521.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Mig-14 HlyE PF06109.13 ORY94521.1 - 0.025 13.9 1.4 1.4 8.1 0.2 2.1 2 0 0 2 2 2 0 Haemolysin E (HlyE) DUF1664 PF07889.12 ORY94521.1 - 0.04 14.0 0.3 0.04 14.0 0.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TSP_NTD PF17804.1 ORY94521.1 - 0.054 13.7 2.2 0.64 10.3 1.6 2.2 1 1 0 1 1 1 0 Tail specific protease N-terminal domain Prismane PF03063.20 ORY94521.1 - 0.11 11.2 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF948 PF06103.11 ORY94521.1 - 0.15 12.3 1.4 0.59 10.4 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CobA_CobO_BtuR PF02572.15 ORY94521.1 - 0.17 12.1 3.0 0.2 11.9 0.2 2.1 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Cyclin_N PF00134.23 ORY94523.1 - 0.0031 17.2 0.2 0.0074 16.0 0.1 1.7 2 1 0 2 2 2 1 Cyclin, N-terminal domain DUF4378 PF14309.6 ORY94523.1 - 0.048 14.0 0.6 0.069 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Hist_deacetyl PF00850.19 ORY94524.1 - 3.1e-82 276.5 0.0 4.3e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Cyclin PF08613.11 ORY94526.1 - 5.7e-08 33.3 1.4 5.7e-08 33.3 1.4 2.7 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY94526.1 - 0.003 17.3 0.3 0.021 14.6 0.3 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain Neur_chan_memb PF02932.16 ORY94526.1 - 6.5 6.7 9.5 1.4 8.9 2.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Chitin_synth_2 PF03142.15 ORY94527.1 - 9.6e-91 305.0 2.5 1e-65 222.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY94527.1 - 0.00012 22.1 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY94527.1 - 0.0011 18.8 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.28 ORY94527.1 - 0.0011 19.1 0.1 4.9 7.4 0.0 3.3 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.6 ORY94527.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF1189 PF06691.11 ORY94527.1 - 0.22 11.1 6.0 0.42 10.2 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) MCM PF00493.23 ORY94529.1 - 2e-103 344.3 0.1 3.3e-103 343.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY94529.1 - 6.1e-38 129.5 0.1 1.1e-37 128.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY94529.1 - 1.8e-26 92.4 0.4 4.5e-26 91.1 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 ORY94529.1 - 2.8e-17 63.4 9.4 2.8e-17 63.4 9.4 3.6 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 ORY94529.1 - 5.4e-14 52.6 0.1 2e-13 50.8 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY94529.1 - 6.7e-10 38.7 0.1 9.8e-07 28.4 0.0 3.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY94529.1 - 2e-05 24.6 0.0 5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY94529.1 - 5.8e-05 23.0 0.4 0.00054 19.8 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY94529.1 - 0.011 15.5 0.1 0.1 12.3 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_lid_2 PF17863.1 ORY94529.1 - 0.03 14.1 0.4 0.03 14.1 0.4 3.2 3 0 0 3 3 3 0 AAA lid domain AAA PF00004.29 ORY94529.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Yippee-Mis18 PF03226.14 ORY94529.1 - 0.15 12.3 0.2 0.33 11.2 0.2 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FXR_C1 PF16096.5 ORY94529.1 - 1.1 9.6 4.1 1.4 9.2 1.0 2.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 2OG-FeII_Oxy_2 PF13532.6 ORY94530.1 - 6.2e-09 36.3 0.0 6.5e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Brix PF04427.18 ORY94531.1 - 4.3e-35 121.6 0.2 5.7e-35 121.2 0.2 1.1 1 0 0 1 1 1 1 Brix domain Exo_endo_phos_2 PF14529.6 ORY94532.1 - 0.0022 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase MFS_1 PF07690.16 ORY94533.1 - 2.6e-51 174.6 26.7 2.6e-51 174.6 26.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY94533.1 - 2.6e-09 36.4 9.2 2.6e-09 36.4 9.2 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DAD PF02109.16 ORY94533.1 - 0.11 12.9 1.7 0.62 10.4 0.0 2.4 2 0 0 2 2 2 0 DAD family AAR2 PF05282.11 ORY94534.1 - 1.5e-101 340.3 0.3 4.4e-101 338.8 0.3 1.6 1 1 0 1 1 1 1 AAR2 protein Amidohydro_1 PF01979.20 ORY94535.1 - 6.6e-66 223.0 0.0 7.8e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY94535.1 - 7.5e-10 38.9 0.4 1.5e-06 27.9 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family UDPGP PF01704.18 ORY94536.1 - 5.4e-198 657.7 0.4 6.3e-198 657.5 0.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase WXG100 PF06013.12 ORY94536.1 - 0.069 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG 60KD_IMP PF02096.20 ORY94536.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein rRNA_processing PF08524.11 ORY94537.1 - 1.4e-09 38.2 33.4 1.3e-07 31.7 33.4 2.1 1 1 0 1 1 1 1 rRNA processing RR_TM4-6 PF06459.12 ORY94537.1 - 1.6 8.5 16.1 2 8.1 16.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ARD PF03079.14 ORY94537.1 - 6.1 7.0 12.0 0.91 9.7 7.4 1.8 2 0 0 2 2 2 0 ARD/ARD' family Fibrillarin PF01269.17 ORY94538.1 - 3.2e-107 356.8 0.1 3.9e-107 356.5 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORY94538.1 - 3.8e-05 23.5 0.1 5.4e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORY94538.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 ORY94538.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY94538.1 - 0.044 13.9 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 ORY94538.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain RRS1 PF04939.12 ORY94539.1 - 5.6e-56 188.9 9.3 5.6e-56 188.9 9.3 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Cyclin_N PF00134.23 ORY94540.1 - 0.00017 21.3 0.1 0.0002 21.1 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain AtuA PF07287.11 ORY94541.1 - 1.7e-105 352.6 0.1 2.4e-105 352.1 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Kinesin PF00225.23 ORY94542.1 - 2.2e-17 63.0 0.0 2.8e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY94542.1 - 6.1e-12 45.7 0.0 9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding MAGP PF05507.11 ORY94542.1 - 0.18 12.2 0.6 0.94 9.9 0.2 2.0 1 1 1 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Kinesin PF00225.23 ORY94543.1 - 5.1e-78 262.3 3.0 5.1e-78 262.3 3.0 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY94543.1 - 8.5e-07 29.0 0.1 6.8e-06 26.1 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding FPP PF05911.11 ORY94543.1 - 0.00089 17.6 24.2 0.0014 16.9 24.2 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil SPT16 PF08644.11 ORY94543.1 - 0.079 13.1 0.4 0.079 13.1 0.4 2.7 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) AAA_15 PF13175.6 ORY94543.1 - 0.17 11.6 5.9 0.38 10.4 5.9 1.5 1 0 0 1 1 1 0 AAA ATPase domain UPF1_Zn_bind PF09416.10 ORY94544.1 - 2.8e-75 251.4 5.1 4.6e-75 250.7 4.5 1.7 2 0 0 2 2 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 ORY94544.1 - 1.5e-57 194.4 0.0 2.7e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY94544.1 - 1.4e-46 159.4 4.4 1e-24 87.8 0.8 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 ORY94544.1 - 6.4e-34 116.1 0.0 1.4e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 ORY94544.1 - 4.2e-14 52.7 0.0 1.9e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY94544.1 - 3.3e-11 43.7 0.0 9.5e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY94544.1 - 3.6e-06 26.9 0.1 0.056 13.2 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 ORY94544.1 - 2.7e-05 24.2 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORY94544.1 - 0.00016 21.3 0.0 0.0049 16.4 0.0 2.8 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 ORY94544.1 - 0.00041 19.7 1.2 0.0057 15.9 0.1 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 ORY94544.1 - 0.00074 19.4 0.0 0.0015 18.4 0.0 1.6 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 ORY94544.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.7 ORY94544.1 - 0.017 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 ORY94544.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 ORY94544.1 - 0.048 13.4 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 ORY94544.1 - 0.12 11.9 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 ORY94544.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S13_N PF08069.12 ORY94544.1 - 0.14 12.2 0.2 0.43 10.6 0.0 1.9 2 0 0 2 2 1 0 Ribosomal S13/S15 N-terminal domain ArsA_ATPase PF02374.15 ORY94544.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase ATPase PF06745.13 ORY94544.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 ORY94544.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Prok-RING_2 PF14445.6 ORY94544.1 - 0.23 11.7 2.3 0.61 10.3 2.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Kelch_3 PF13415.6 ORY94545.1 - 1.1e-11 44.7 8.1 4.2e-06 26.9 0.6 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY94545.1 - 7.9e-11 41.9 11.2 3.5e-06 27.1 0.1 6.3 5 1 1 6 6 6 2 Kelch motif Kelch_5 PF13854.6 ORY94545.1 - 2.1e-07 30.8 8.7 0.00048 20.1 0.3 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 ORY94545.1 - 5.8e-07 29.4 21.1 0.0016 18.4 0.2 6.5 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY94545.1 - 1.7e-05 24.6 2.9 0.0074 16.2 0.1 5.0 6 1 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 ORY94545.1 - 0.00013 21.5 4.4 0.019 14.5 0.3 4.6 5 0 0 5 5 5 1 Kelch motif 7tm_7 PF08395.12 ORY94545.1 - 0.0031 16.8 3.5 0.0066 15.7 1.0 2.1 2 0 0 2 2 2 1 7tm Chemosensory receptor YqhR PF11085.8 ORY94545.1 - 0.011 15.7 0.2 0.011 15.7 0.2 1.9 2 0 0 2 2 2 0 Conserved membrane protein YqhR LPG_synthase_TM PF03706.13 ORY94545.1 - 0.07 12.6 6.2 0.12 11.8 4.2 1.9 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Syndecan PF01034.20 ORY94545.1 - 0.15 12.0 0.8 0.43 10.5 0.8 1.7 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.9 ORY94545.1 - 4.3 6.0 7.6 61 2.2 0.0 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) zf-RING_2 PF13639.6 ORY94546.1 - 9e-10 38.7 8.2 9e-10 38.7 8.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORY94546.1 - 2.3e-06 27.8 9.1 1.4e-05 25.2 7.3 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORY94546.1 - 9e-06 25.3 1.7 9e-06 25.3 1.7 2.9 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY94546.1 - 2.7e-05 23.9 7.1 2.7e-05 23.9 7.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY94546.1 - 6.5e-05 22.7 6.1 6.5e-05 22.7 6.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY94546.1 - 0.00019 21.4 2.4 0.00019 21.4 2.4 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY94546.1 - 0.0017 18.3 5.8 0.0017 18.3 5.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 ORY94546.1 - 0.0043 16.6 7.7 0.0043 16.6 7.7 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 ORY94546.1 - 0.0081 16.0 11.0 0.0089 15.9 8.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY94546.1 - 0.01 15.8 8.5 0.08 13.0 7.3 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Endonuclease_7 PF02945.15 ORY94546.1 - 0.13 12.2 3.7 0.24 11.4 3.7 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII Zf_RING PF16744.5 ORY94546.1 - 0.23 11.6 5.5 0.15 12.2 1.8 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C3H2C3 PF17122.5 ORY94546.1 - 0.33 11.0 4.5 1.3 9.1 4.5 2.0 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 ORY94546.1 - 2.1 8.5 11.9 12 6.1 0.5 2.6 2 0 0 2 2 2 0 RING-variant domain Prok-RING_4 PF14447.6 ORY94546.1 - 2.5 8.0 10.6 18 5.3 8.6 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 ORY94546.1 - 4.3 7.4 8.5 0.48 10.4 1.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Aa_trans PF01490.18 ORY94548.1 - 1.5e-68 231.4 27.2 2e-68 231.0 27.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_25 PF13649.6 ORY94549.1 - 4.3e-09 37.0 0.0 9.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY94549.1 - 1.1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY94549.1 - 4e-08 33.8 0.0 7.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY94549.1 - 3.8e-06 26.5 0.0 1.3e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 ORY94549.1 - 4.5e-06 26.6 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY94549.1 - 0.0037 18.0 0.0 0.0085 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORY94549.1 - 0.04 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 ORY94549.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Arrestin_N PF00339.29 ORY94550.1 - 0.00021 21.4 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 ORY94551.1 - 2.1e-51 174.8 0.2 5.1e-51 173.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94551.1 - 2.1e-38 132.1 0.0 3.4e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 ORY94551.1 - 5.5e-05 23.3 0.1 0.00014 22.0 0.1 1.7 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain DUF4407 PF14362.6 ORY94551.1 - 0.0061 16.0 4.9 0.0092 15.4 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF484 PF04340.12 ORY94551.1 - 0.041 13.6 2.1 0.086 12.5 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Cytochrom_C_2 PF01322.20 ORY94551.1 - 0.1 13.5 1.6 0.21 12.5 1.0 1.9 1 1 0 1 1 1 0 Cytochrome C' GH114_assoc PF14741.6 ORY94551.1 - 0.11 12.8 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain DUF1176 PF06674.11 ORY94551.1 - 0.22 10.9 3.1 0.14 11.6 0.6 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1176) Uso1_p115_C PF04871.13 ORY94551.1 - 0.29 11.5 11.3 0.68 10.3 3.7 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region OmpH PF03938.14 ORY94551.1 - 3.3 8.1 7.5 8.6 6.7 7.5 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 ORY94551.1 - 4.1 6.9 8.2 7.7 6.0 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.6 ORY94551.1 - 6.1 7.0 13.5 9.7 6.4 13.0 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit adh_short PF00106.25 ORY94552.1 - 6.3e-08 32.3 0.0 7.5e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY94552.1 - 3.7e-05 23.4 0.0 0.00024 20.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY94552.1 - 0.013 15.4 0.3 0.027 14.4 0.1 1.6 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 ORY94552.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RRM_1 PF00076.22 ORY94553.1 - 6.5e-19 67.5 0.0 9.3e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY94553.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 ORY94553.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.18 ORY94554.1 - 8.2e-93 310.7 0.1 8.2e-93 310.7 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY94554.1 - 1.3e-09 38.1 0.3 1.1e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY94554.1 - 4e-06 26.9 0.7 0.00032 20.6 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ORY94554.1 - 7.6e-05 23.0 1.3 0.0003 21.1 0.0 2.5 2 2 1 3 3 3 1 AAA domain Dynamin_N PF00350.23 ORY94554.1 - 0.00023 21.3 3.8 0.16 12.0 0.0 3.3 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 ORY94554.1 - 0.00031 20.1 0.6 0.0012 18.3 0.0 2.2 3 0 0 3 3 3 1 AIG1 family FtsK_SpoIIIE PF01580.18 ORY94554.1 - 0.00043 19.7 0.2 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.26 ORY94554.1 - 0.00045 20.0 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain IIGP PF05049.13 ORY94554.1 - 0.0014 17.8 0.0 0.0033 16.5 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 ORY94554.1 - 0.0018 17.9 2.1 0.32 10.5 0.0 3.4 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF87 PF01935.17 ORY94554.1 - 0.014 15.5 0.8 0.43 10.6 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 ORY94554.1 - 0.017 15.6 0.1 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 ORY94554.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 ORY94554.1 - 0.018 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORY94554.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_32 PF13654.6 ORY94554.1 - 0.045 12.5 8.0 0.73 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY94554.1 - 0.052 13.6 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 ORY94554.1 - 0.081 13.3 10.5 0.18 12.1 10.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.8 ORY94554.1 - 0.095 13.4 4.3 0.2 12.4 4.3 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Bacillus_HBL PF05791.11 ORY94554.1 - 0.098 12.5 2.7 0.18 11.6 2.7 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) RNA_helicase PF00910.22 ORY94554.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase UPF0242 PF06785.11 ORY94554.1 - 0.18 11.9 8.3 0.33 11.0 8.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 ORY94554.1 - 0.2 12.1 8.2 4.8 7.6 3.4 2.4 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 ORY94554.1 - 0.23 11.2 2.5 1.2 8.9 2.5 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF4407 PF14362.6 ORY94554.1 - 0.54 9.5 6.0 0.87 8.9 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Adhesin_P1_N PF18652.1 ORY94554.1 - 0.58 10.2 2.8 1 9.4 0.8 2.2 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain PP_kinase_N PF13089.6 ORY94554.1 - 0.76 10.1 6.6 9.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Mit_KHE1 PF10173.9 ORY94554.1 - 0.98 9.5 4.1 5.7 7.0 3.1 2.1 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related MFS_1 PF07690.16 ORY94555.1 - 1.1e-23 83.7 24.5 1.6e-23 83.2 24.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ARS2 PF04959.13 ORY94556.1 - 3.7e-23 82.9 0.6 1.2e-22 81.3 0.1 2.1 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 ORY94556.1 - 1.6e-19 70.1 8.5 1.6e-19 70.1 8.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 ORY94556.1 - 9.9e-10 38.1 5.4 2.7e-09 36.7 4.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 ORY94556.1 - 0.00039 20.2 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HrpF PF06266.12 ORY94556.1 - 0.099 12.9 0.2 9.4 6.6 0.1 2.9 2 0 0 2 2 2 0 HrpF protein zf-C2H2_3rep PF18868.1 ORY94556.1 - 0.34 11.6 2.5 0.87 10.3 0.7 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats RNaseH_C PF09293.10 ORY94557.1 - 0.11 12.9 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 T4 RNase H, C terminal Pkinase PF00069.25 ORY94558.1 - 1.1e-70 238.1 0.0 1.7e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94558.1 - 2.1e-33 115.7 0.0 3.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY94558.1 - 0.00014 21.3 0.0 0.00014 21.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY94558.1 - 0.0097 14.9 0.2 0.015 14.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain SUIM_assoc PF16619.5 ORY94558.1 - 0.028 14.5 8.4 0.07 13.2 8.4 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 ORY94558.1 - 6.3 6.3 17.0 11 5.5 17.0 1.3 1 0 0 1 1 1 0 Spt20 family F-box-like PF12937.7 ORY94559.1 - 5.1e-08 32.7 0.0 5.1e-08 32.7 0.0 2.9 5 0 0 5 5 5 1 F-box-like F-box PF00646.33 ORY94559.1 - 4.7e-05 23.1 0.5 0.00027 20.7 0.0 2.6 2 0 0 2 2 2 1 F-box domain Homeodomain PF00046.29 ORY94560.1 - 5.9e-20 70.9 1.0 1.4e-19 69.7 1.0 1.7 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORY94560.1 - 0.0017 18.1 0.9 0.0041 16.9 0.9 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 ORY94560.1 - 0.0033 17.3 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain RskA PF10099.9 ORY94560.1 - 0.065 13.5 14.7 0.029 14.7 11.7 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA YdaS_antitoxin PF15943.5 ORY94560.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Glyco_hydro_17 PF00332.18 ORY94561.1 - 2.4e-14 53.7 0.0 1.9e-11 44.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 MMR_HSR1_Xtn PF16897.5 ORY94561.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Tax PF02959.16 ORY94561.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 HTLV Tax GATA PF00320.27 ORY94562.1 - 1.4e-06 27.8 6.3 2.9e-06 26.8 6.3 1.5 1 0 0 1 1 1 1 GATA zinc finger NMD3 PF04981.13 ORY94562.1 - 0.066 12.7 0.7 0.13 11.7 0.7 1.4 1 0 0 1 1 1 0 NMD3 family zf-C2H2 PF00096.26 ORY94563.1 - 2.7e-08 33.8 35.3 0.004 17.5 0.4 6.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY94563.1 - 3.2e-08 33.7 36.3 0.045 14.6 0.2 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger FOXP-CC PF16159.5 ORY94563.1 - 3.4e-05 24.4 17.3 0.00089 19.8 1.0 4.3 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORY94563.1 - 7.6e-05 23.0 31.2 0.13 12.7 0.1 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 ORY94563.1 - 0.00072 19.7 2.2 0.00072 19.7 2.2 2.7 1 1 0 2 2 2 1 Aberrant zinc-finger zf-Di19 PF05605.12 ORY94563.1 - 0.012 15.9 21.9 0.86 9.9 2.0 4.6 3 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORY94563.1 - 0.48 10.8 19.9 2.4 8.5 1.4 5.3 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY94563.1 - 1.4 9.4 0.1 1.4 9.4 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-BED PF02892.15 ORY94563.1 - 1.7 8.7 14.7 2.9 8.0 1.1 3.9 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.6 ORY94563.1 - 3.3 7.8 20.7 1.7 8.7 1.6 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger Methyltransf_25 PF13649.6 ORY94565.1 - 2.3e-18 66.7 0.0 6.4e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY94565.1 - 5.3e-16 59.0 0.0 9.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY94565.1 - 8.1e-15 54.9 0.0 3.2e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY94565.1 - 5.4e-14 52.4 0.0 6.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY94565.1 - 4.4e-11 43.4 0.0 1.1e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY94565.1 - 4.1e-07 29.6 0.0 8.4e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY94565.1 - 9.1e-07 28.5 0.0 9.6e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 ORY94565.1 - 1.5e-06 27.6 0.0 2.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 ORY94565.1 - 2.4e-06 27.2 0.0 0.0007 19.1 0.0 2.1 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain MetW PF07021.12 ORY94565.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 ORY94565.1 - 0.00024 19.8 0.0 0.0027 16.3 0.0 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 ORY94565.1 - 0.00044 19.8 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 ORY94565.1 - 0.00054 19.9 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 ORY94565.1 - 0.0044 17.1 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 ORY94565.1 - 0.0098 14.8 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ORY94565.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 ORY94565.1 - 0.078 12.6 0.1 2 8.1 0.1 2.1 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltr_RsmB-F PF01189.17 ORY94566.1 - 7.2e-69 231.4 0.0 1.3e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 ORY94566.1 - 1.3e-06 28.8 0.0 3.7e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 ORY94566.1 - 4.4e-06 26.6 0.1 8.7e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 ORY94566.1 - 0.0086 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 ORY94566.1 - 0.034 14.8 0.0 0.1 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORY94566.1 - 0.034 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ripply PF14998.6 ORY94566.1 - 0.11 13.2 0.1 0.11 13.2 0.1 2.5 2 0 0 2 2 2 0 Transcription Regulator BUD22 PF09073.10 ORY94566.1 - 2.9 7.1 29.2 4.5 6.5 29.2 1.3 1 0 0 1 1 1 0 BUD22 MAPEG PF01124.18 ORY94567.1 - 3.5e-06 26.9 5.6 4.8e-06 26.5 5.6 1.1 1 0 0 1 1 1 1 MAPEG family RRM_1 PF00076.22 ORY94568.1 - 4.1e-56 186.7 0.0 6.2e-18 64.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY94568.1 - 1.4e-10 40.9 0.0 1.4e-07 31.3 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY94568.1 - 1.6e-08 34.2 0.0 0.00032 20.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY94568.1 - 5.2e-05 23.2 0.0 0.17 11.9 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 ORY94568.1 - 0.0017 18.0 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 ORY94568.1 - 0.0038 17.3 2.0 1.2 9.3 0.0 3.6 4 1 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 ORY94568.1 - 0.018 15.1 0.2 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.10 ORY94568.1 - 0.067 13.3 0.0 18 5.5 0.0 2.8 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) PHM7_cyt PF14703.6 ORY94568.1 - 0.4 10.9 5.6 5.6 7.2 0.0 3.6 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter PPR_2 PF13041.6 ORY94569.1 - 1.4e-06 28.4 0.1 0.0012 19.0 0.0 4.5 5 1 0 5 5 5 1 PPR repeat family PPR_1 PF12854.7 ORY94569.1 - 0.0001 21.9 1.1 0.0071 16.0 0.2 3.1 3 0 0 3 3 3 1 PPR repeat PPR PF01535.20 ORY94569.1 - 0.00042 20.4 2.2 3.1 8.2 0.0 5.1 6 0 0 6 6 6 2 PPR repeat TPR_19 PF14559.6 ORY94569.1 - 0.057 13.9 0.0 13 6.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 ORY94569.1 - 0.087 12.9 0.0 6.2 7.0 0.0 3.7 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Sec7 PF01369.20 ORY94570.1 - 6.7e-70 234.5 0.2 3.3e-69 232.3 0.1 2.4 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 ORY94570.1 - 6.6e-43 146.3 1.4 6.6e-43 146.3 1.4 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY94570.1 - 4.7e-33 112.9 14.7 1.6e-31 108.0 0.1 6.4 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 ORY94570.1 - 7.2e-22 77.9 2.7 7.2e-22 77.9 2.7 2.6 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 ORY94570.1 - 0.0011 17.2 0.5 0.0028 15.9 0.0 1.8 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Zn_clus PF00172.18 ORY94571.1 - 8.8e-05 22.6 9.2 0.00019 21.5 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORY94571.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 ORY94572.1 - 9.3e-13 48.1 0.0 7.2e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Bromodomain PF00439.25 ORY94572.1 - 1.1e-11 44.7 0.0 2.6e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Pkinase_Tyr PF07714.17 ORY94572.1 - 2.7e-05 23.6 0.1 0.02 14.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ORY94572.1 - 0.00048 19.5 0.3 0.00088 18.7 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY94572.1 - 0.06 12.1 0.8 0.075 11.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 ORY94573.1 - 1.1e-55 188.9 0.0 8.7e-33 113.8 0.0 3.3 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94573.1 - 1.8e-29 102.8 0.0 4e-20 72.2 0.0 3.3 2 1 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 ORY94573.1 - 0.00014 21.3 1.1 0.46 9.8 0.0 3.4 4 0 0 4 4 4 2 Kinase-like Pkinase_fungal PF17667.1 ORY94573.1 - 0.00083 18.2 4.9 0.0016 17.3 0.0 3.0 3 1 0 3 3 3 1 Fungal protein kinase zf-RING_2 PF13639.6 ORY94574.1 - 3e-10 40.2 0.6 6.4e-10 39.2 0.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY94574.1 - 6.4e-10 38.6 1.7 6.4e-10 38.6 1.7 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY94574.1 - 8.2e-06 25.6 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 ORY94574.1 - 8.2e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 ORY94574.1 - 1.5e-05 24.8 0.6 2.6e-05 24.0 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY94574.1 - 8.8e-05 22.7 0.9 0.00026 21.2 0.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY94574.1 - 0.00061 19.8 0.3 0.0013 18.7 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY94574.1 - 0.0018 18.2 0.2 0.0031 17.4 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 ORY94574.1 - 0.015 15.5 0.6 0.036 14.2 0.6 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY94574.1 - 0.019 14.6 0.7 0.039 13.6 0.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 ORY94574.1 - 0.053 13.6 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2681 PF10883.8 ORY94574.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) TMEM51 PF15345.6 ORY94574.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Pkinase PF00069.25 ORY94575.1 - 4e-57 193.6 0.0 5.9e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94575.1 - 7.7e-28 97.5 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 ORY94575.1 - 1.2e-05 25.3 0.2 7e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 PX domain Pkinase_C PF00433.24 ORY94575.1 - 1.9e-05 25.3 0.4 1.9e-05 25.3 0.4 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 ORY94575.1 - 0.00017 20.5 0.1 0.00033 19.6 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORY94575.1 - 0.00019 21.1 0.0 0.5 9.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORY94575.1 - 0.00097 18.5 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY94575.1 - 0.002 17.1 0.1 0.002 17.1 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Peptidase_S8 PF00082.22 ORY94577.1 - 5.9e-41 140.7 7.9 1.1e-40 139.7 7.9 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY94577.1 - 1.8e-14 54.2 0.0 3.7e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 ECH_1 PF00378.20 ORY94578.1 - 7.7e-60 202.3 0.0 9.6e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY94578.1 - 4.3e-30 105.4 0.1 3.2e-28 99.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF218 PF02698.17 ORY94579.1 - 0.00021 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain FrpC PF06901.12 ORY94579.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC DUF247 PF03140.15 ORY94579.1 - 0.29 10.3 0.2 0.76 8.9 0.1 1.4 1 1 0 1 1 1 0 Plant protein of unknown function Ribosomal_L30 PF00327.20 ORY94581.1 - 5.7e-18 64.6 1.7 5.7e-18 64.6 1.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 ORY94581.1 - 6.8e-17 61.5 18.4 1.2e-16 60.7 18.4 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF2486 PF10667.9 ORY94581.1 - 0.054 13.7 4.6 0.07 13.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Tipalpha PF16753.5 ORY94581.1 - 0.3 10.9 3.5 12 5.7 0.0 2.2 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter DAP PF15228.6 ORY94584.1 - 6.8e-06 27.2 3.2 9.4e-06 26.7 3.2 1.2 1 0 0 1 1 1 1 Death-associated protein E7 PF00527.18 ORY94584.1 - 0.34 11.1 4.7 0.5 10.6 4.7 1.2 1 0 0 1 1 1 0 E7 protein, Early protein PAC1 PF16094.5 ORY94584.1 - 2.6 7.1 6.5 3.4 6.7 6.5 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Pyr_redox_2 PF07992.14 ORY94585.1 - 1.2e-51 175.7 0.0 1.6e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY94585.1 - 7.7e-12 45.6 0.1 7.4e-11 42.5 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY94585.1 - 6.1e-05 22.4 0.0 0.085 12.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY94585.1 - 0.051 12.3 0.6 0.28 9.9 0.0 2.0 1 1 1 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 ORY94585.1 - 0.2 11.7 0.9 11 6.0 0.5 3.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding zf-met PF12874.7 ORY94587.1 - 2.8e-07 30.7 9.0 0.0016 18.7 0.1 3.2 3 1 1 4 4 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY94587.1 - 2.7e-06 27.5 11.2 0.0015 18.8 1.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY94587.1 - 7.6e-06 26.3 15.0 0.016 16.0 1.9 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY94587.1 - 2e-05 24.8 20.0 0.00049 20.4 1.0 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.7 ORY94587.1 - 0.0031 17.5 0.6 0.0031 17.5 0.6 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.6 ORY94587.1 - 0.018 15.0 0.5 0.018 15.0 0.5 3.6 5 0 0 5 5 4 0 C2H2-type zinc finger zf_UBZ PF18439.1 ORY94587.1 - 0.031 13.9 8.6 0.52 9.9 0.2 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF629 PF04780.12 ORY94587.1 - 0.14 10.7 6.9 0.61 8.5 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Actin_micro PF17003.5 ORY94587.1 - 1.2 8.2 6.2 6.3 5.9 6.2 2.0 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_2 PF12756.7 ORY94587.1 - 1.3 9.4 11.7 1.2 9.5 0.8 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 ORY94587.1 - 1.5 8.7 8.8 37 4.2 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type OrfB_Zn_ribbon PF07282.11 ORY94587.1 - 2.8 7.9 7.4 0.31 11.0 1.9 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.12 ORY94587.1 - 3.7 7.6 10.7 57 3.8 8.8 2.8 1 1 1 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 ORY94587.1 - 3.9 7.7 13.0 25 5.1 0.0 3.7 4 1 1 5 5 5 0 Zinc ribbon domain EF-hand_13 PF17958.1 ORY94589.1 - 2.6e-23 81.6 0.0 5.6e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 ORY94589.1 - 2.9e-13 50.1 3.9 1.1e-12 48.2 0.0 3.6 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY94589.1 - 0.00024 20.5 0.4 0.0007 19.0 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 ORY94589.1 - 0.00043 19.6 0.0 0.0033 16.9 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 ORY94589.1 - 0.0023 17.7 0.0 0.0091 15.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY94589.1 - 0.0064 16.3 0.0 0.053 13.5 0.0 2.6 1 0 0 1 1 1 1 EF-hand domain Pkinase PF00069.25 ORY94590.1 - 1.9e-38 132.3 0.1 3.6e-38 131.5 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94590.1 - 1.7e-13 50.4 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY94590.1 - 4.9e-08 32.2 0.3 6.1e-08 31.9 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY94590.1 - 9.5e-05 21.5 0.4 0.00014 21.0 0.4 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY94590.1 - 0.00018 20.9 0.0 0.00042 19.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY94590.1 - 0.00056 19.9 1.5 0.00077 19.5 1.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY94590.1 - 0.00085 18.4 0.4 0.0012 17.9 0.4 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 ORY94590.1 - 0.0012 18.5 1.1 0.0015 18.2 1.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY94590.1 - 0.0042 16.5 0.9 0.0064 15.9 0.9 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NDUF_C2 PF06374.11 ORY94590.1 - 0.013 15.7 0.3 0.026 14.7 0.3 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Choline_kinase PF01633.20 ORY94590.1 - 0.13 11.8 1.1 0.2 11.2 1.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 ORY94591.1 - 0.2 10.9 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_19 PF14559.6 ORY94594.1 - 2.8e-08 34.1 8.6 3.3e-05 24.3 0.3 3.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY94594.1 - 6.1e-08 32.2 9.9 0.0011 18.9 1.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY94594.1 - 6.4e-08 32.8 5.3 0.11 13.4 0.4 4.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY94594.1 - 1.4e-06 28.9 1.5 0.08 13.6 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY94594.1 - 2.5e-05 23.9 8.0 0.02 14.7 1.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY94594.1 - 3.5e-05 23.4 1.9 0.0019 17.8 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.6 ORY94594.1 - 0.00025 21.1 4.1 0.0021 18.2 0.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY94594.1 - 0.0033 17.5 4.8 2.9 8.3 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY94594.1 - 0.006 16.9 9.7 0.31 11.4 0.6 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY94594.1 - 0.039 14.6 1.9 8 7.3 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TAF1_subA PF14929.6 ORY94594.1 - 0.3 10.5 4.9 5.2 6.4 0.1 2.0 1 1 1 2 2 2 0 TAF RNA Polymerase I subunit A ANAPC3 PF12895.7 ORY94594.1 - 0.53 10.5 11.1 0.28 11.4 6.7 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AA_kinase PF00696.28 ORY94595.1 - 6.9e-41 140.4 0.0 9e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family tRNA_bind_3 PF17176.4 ORY94595.1 - 0.036 14.3 0.5 0.084 13.2 0.1 1.8 2 0 0 2 2 2 0 tRNA-binding domain Aminotran_5 PF00266.19 ORY94596.1 - 1.3e-51 175.7 0.0 1.5e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V zf-C2H2_11 PF16622.5 ORY94598.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 ORY94598.1 - 0.25 12.3 3.5 19 6.4 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY94598.1 - 0.26 11.8 1.9 4.6 7.9 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.15 ORY94598.1 - 5.4 7.1 10.7 0.28 11.3 4.5 1.9 1 1 1 2 2 2 0 BED zinc finger Y_phosphatase PF00102.27 ORY94599.1 - 0.012 15.2 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase V-SNARE PF05008.15 ORY94599.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Med4 PF10018.9 ORY94599.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TPR_1 PF00515.28 ORY94600.1 - 5.6e-24 82.9 0.2 2.3e-10 39.8 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY94600.1 - 4.1e-23 79.6 0.3 9e-08 31.7 0.0 4.8 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY94600.1 - 3.2e-17 61.9 0.1 9.4e-07 28.4 0.0 3.7 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 ORY94600.1 - 1.6e-16 59.0 0.4 8.7e-06 25.6 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY94600.1 - 8.5e-16 58.0 0.1 7.3e-07 29.4 0.0 3.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY94600.1 - 2.2e-13 50.5 4.1 5.8e-06 26.7 0.0 3.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY94600.1 - 1.7e-12 47.1 0.5 0.0013 19.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY94600.1 - 1.7e-11 43.9 0.1 0.0037 18.0 0.0 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY94600.1 - 3.7e-10 40.3 0.0 0.00028 21.5 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY94600.1 - 5.6e-09 35.8 1.7 0.021 15.2 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY94600.1 - 8.3e-09 34.9 0.0 0.003 17.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY94600.1 - 8.8e-08 31.8 0.1 0.13 12.2 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY94600.1 - 5e-07 29.9 0.1 1.3e-06 28.6 0.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY94600.1 - 4e-05 23.7 0.0 0.016 15.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Paf67 PF10255.9 ORY94600.1 - 0.0014 17.7 0.1 0.0039 16.2 0.1 1.6 1 1 1 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_4 PF07721.14 ORY94600.1 - 0.0019 18.6 0.1 0.18 12.5 0.0 3.7 5 1 0 5 5 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 ORY94600.1 - 0.0045 16.4 0.1 0.0089 15.5 0.1 1.5 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_21 PF09976.9 ORY94600.1 - 0.0045 16.7 1.1 0.91 9.2 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat-like domain MIT PF04212.18 ORY94600.1 - 0.006 16.6 0.2 0.22 11.6 0.1 2.9 1 1 1 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 ORY94600.1 - 0.0085 16.4 0.9 2 8.8 0.0 3.4 1 1 4 5 5 5 1 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY94600.1 - 0.03 14.1 0.3 0.28 10.9 0.3 2.1 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Vta1_C PF18097.1 ORY94600.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Vta1 C-terminal domain TPR_15 PF13429.6 ORY94600.1 - 0.041 13.1 0.0 0.74 9.0 0.0 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ORY94600.1 - 0.042 13.9 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat Rapsyn_N PF10579.9 ORY94600.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region DUF4810 PF16068.5 ORY94600.1 - 0.12 12.9 0.3 12 6.5 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4810) DUF2856 PF11043.8 ORY94601.1 - 0.0061 16.6 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2856) Rot1 PF10681.9 ORY94601.1 - 0.037 13.6 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal DUF2849 PF11011.8 ORY94601.1 - 0.094 13.4 0.4 0.3 11.8 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) WD40 PF00400.32 ORY94602.1 - 3.5e-36 122.6 17.2 4.4e-07 30.5 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY94602.1 - 4e-13 49.5 0.1 0.0067 16.7 0.0 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY94602.1 - 3.9e-07 30.2 0.2 0.49 10.3 0.0 4.0 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY94602.1 - 9e-07 28.5 2.8 0.0078 15.6 0.1 3.2 1 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 ORY94602.1 - 0.00018 21.1 0.4 0.0029 17.2 0.4 2.1 1 1 0 1 1 1 1 PQQ-like domain Frtz PF11768.8 ORY94602.1 - 0.0002 19.8 0.1 0.065 11.5 0.0 2.5 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 ORY94602.1 - 0.0066 15.1 1.5 0.44 9.1 0.1 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ PF01011.21 ORY94602.1 - 0.043 13.7 0.0 10 6.2 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat BBS2_Mid PF14783.6 ORY94602.1 - 0.12 12.4 0.3 47 4.1 0.0 3.7 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 ORY94602.1 - 0.23 12.0 1.5 15 6.2 0.1 3.5 3 0 0 3 3 3 0 PQQ-like domain NUDIX PF00293.28 ORY94603.1 - 6.3e-16 58.6 0.1 1.3e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 ORY94603.1 - 2.7e-14 53.7 0.0 8e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ORY94603.1 - 5.8e-08 32.3 1.0 9.9e-08 31.5 1.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_2 PF12796.7 ORY94603.1 - 1.2e-07 32.2 0.0 2.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY94603.1 - 3.7e-05 23.9 0.0 0.00013 22.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY94603.1 - 5.5e-05 23.6 0.1 0.00062 20.3 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY94603.1 - 0.0015 18.8 0.0 0.0062 17.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 ORY94603.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Tetraspanin PF00335.20 ORY94604.1 - 7.6e-11 42.2 16.1 3.6e-10 39.9 16.2 2.0 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 ORY94604.1 - 0.69 9.6 6.8 3.2 7.4 6.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2981) DUF2650 PF10853.8 ORY94604.1 - 9.7 6.0 9.7 12 5.7 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2650) Fungal_trans PF04082.18 ORY94605.1 - 9.7e-07 28.1 0.2 3e-06 26.5 0.2 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY94605.1 - 0.005 16.9 7.8 0.005 16.9 7.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 ORY94605.1 - 0.17 11.9 19.1 0.028 14.4 8.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 ORY94605.1 - 9.1 5.9 9.2 3 7.5 5.6 2.0 2 0 0 2 2 2 0 FAM176 family CBS PF00571.28 ORY94606.1 - 1.8e-23 82.8 5.7 5.9e-10 39.4 0.1 4.7 5 0 0 5 5 5 4 CBS domain zf-LITAF-like PF10601.9 ORY94607.1 - 4.4e-19 68.5 11.3 6e-19 68.1 11.3 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Prok-RING_1 PF14446.6 ORY94607.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.12 ORY94607.1 - 0.58 10.2 0.0 0.58 10.2 0.0 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon UPF0547 PF10571.9 ORY94607.1 - 0.66 10.1 0.0 0.66 10.1 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Sgf11 PF08209.11 ORY94607.1 - 3.1 7.4 12.6 3.2 7.4 0.2 3.2 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 ORY94607.1 - 4.1 7.1 9.9 3.2 7.4 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger YacG PF03884.14 ORY94607.1 - 4.4 7.1 10.2 9.8 6.0 0.2 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Pkinase PF00069.25 ORY94608.1 - 3e-57 194.0 0.1 5.6e-57 193.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94608.1 - 1.9e-43 148.7 0.1 3.5e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 ORY94608.1 - 1.2e-05 25.5 0.3 0.00014 22.0 0.1 2.6 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 ORY94608.1 - 0.0043 15.9 0.0 0.008 15.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase AAA_23 PF13476.6 ORY94608.1 - 9.8 6.6 8.1 5.4 7.5 5.2 2.0 2 1 0 2 2 2 0 AAA domain Cornichon PF03311.14 ORY94609.1 - 9e-41 139.0 3.8 1.7e-40 138.1 3.8 1.4 1 0 0 1 1 1 1 Cornichon protein CSN8_PSD8_EIF3K PF10075.9 ORY94609.1 - 8.3e-31 106.9 1.0 1.1e-30 106.5 0.1 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 ORY94609.1 - 1.5e-06 27.8 0.1 2.4e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP family TFIIF_alpha PF05793.12 ORY94610.1 - 2.9 6.4 54.0 0.007 15.0 14.8 3.1 2 1 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleo_P87 PF07267.11 ORY94611.1 - 0.046 12.6 0.5 0.055 12.3 0.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1640 PF07798.11 ORY94612.1 - 7.2e-43 146.6 1.6 1.1e-42 146.0 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PRT_C PF08372.10 ORY94612.1 - 0.033 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal ApoLp-III PF07464.11 ORY94612.1 - 0.081 13.0 3.3 0.17 11.9 3.0 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 ORY94612.1 - 0.3 11.1 8.8 0.38 10.8 5.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM76 PF16046.5 ORY94612.1 - 8.8 5.6 7.4 25 4.1 7.4 1.7 1 1 0 1 1 1 0 FAM76 protein PhoD PF09423.10 ORY94613.1 - 4.3e-05 22.7 0.0 0.0043 16.1 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Ribosomal_L14e PF01929.17 ORY94614.1 - 2.1e-30 105.0 1.8 3e-30 104.5 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 DUF917 PF06032.12 ORY94614.1 - 0.016 14.1 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF917) PIN_4 PF13638.6 ORY94615.1 - 2.2e-09 37.7 0.3 1.1e-05 25.7 0.2 2.4 2 1 0 2 2 2 2 PIN domain SDA1 PF05285.12 ORY94615.1 - 0.0018 17.8 9.7 0.002 17.6 9.7 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 ORY94615.1 - 0.015 14.7 10.8 0.016 14.6 10.8 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 ORY94615.1 - 0.02 13.2 6.1 0.033 12.5 6.1 1.4 1 0 0 1 1 1 0 CDC45-like protein zf-SCNM1 PF15803.5 ORY94615.1 - 0.021 14.4 1.0 0.039 13.6 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 Nop14 PF04147.12 ORY94615.1 - 0.052 11.8 14.6 0.063 11.5 14.6 1.2 1 0 0 1 1 1 0 Nop14-like family DUF169 PF02596.15 ORY94615.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 N-SET PF11764.8 ORY94615.1 - 0.99 9.5 8.2 1.9 8.5 8.2 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N EST1_DNA_bind PF10373.9 ORY94616.1 - 6.4e-20 71.8 0.1 5.5e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 ORY94616.1 - 1.5e-10 41.8 0.3 7.9e-10 39.5 0.1 2.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 Ribosomal_S27e PF01667.17 ORY94618.1 - 6.7e-30 102.6 2.2 8.4e-30 102.3 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORY94618.1 - 0.00054 19.4 3.0 0.00083 18.8 3.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.21 ORY94618.1 - 0.025 14.8 0.7 0.036 14.3 0.7 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 ORY94618.1 - 0.025 14.5 2.1 0.042 13.8 2.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.6 ORY94618.1 - 0.081 12.9 2.0 2.6 8.1 2.0 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2HC5 PF06221.13 ORY94618.1 - 0.16 12.0 3.9 0.16 12.0 2.3 1.8 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Na_sulph_symp PF00939.19 ORY94619.1 - 4.5e-30 105.1 37.7 6.6e-30 104.6 37.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 ORY94619.1 - 3.8e-29 102.8 14.0 1.4e-12 48.3 1.5 3.1 1 1 2 3 3 3 3 SPX domain CitMHS PF03600.16 ORY94619.1 - 1.5e-26 93.3 56.0 2.6e-22 79.4 29.9 2.8 1 1 1 3 3 3 2 Citrate transporter CorA PF01544.18 ORY94619.1 - 1.8 7.8 5.0 1.1 8.5 0.8 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Ish1 PF10281.9 ORY94620.1 - 4e-05 23.8 0.2 4e-05 23.8 0.2 2.1 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Apolipoprotein PF01442.18 ORY94620.1 - 0.011 15.6 30.8 0.013 15.4 7.4 4.3 1 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain ApoO PF09769.9 ORY94620.1 - 0.23 11.4 6.0 12 5.8 0.1 4.7 4 2 2 6 6 6 0 Apolipoprotein O DUF2115 PF09888.9 ORY94620.1 - 1.2 9.6 3.9 2.2 8.8 0.3 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) YtxH PF12732.7 ORY94620.1 - 1.4 9.5 14.3 1.7e+02 2.8 0.0 5.2 2 2 0 2 2 2 0 YtxH-like protein Pkinase PF00069.25 ORY94621.1 - 2.2e-73 246.9 0.1 5.5e-73 245.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94621.1 - 6.9e-40 137.0 0.0 1.7e-39 135.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORY94621.1 - 1.6e-12 47.0 0.1 3.3e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORY94621.1 - 1.5e-08 34.3 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY94621.1 - 0.00063 19.7 0.0 0.0021 18.0 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY94621.1 - 0.019 13.9 0.2 0.019 13.9 0.2 1.7 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 ORY94621.1 - 0.047 13.3 2.3 0.069 12.7 0.1 2.2 2 0 0 2 2 2 0 RIO1 family DUF2786 PF10979.8 ORY94621.1 - 0.096 12.6 4.9 0.23 11.4 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Ribosomal_L37e PF01907.19 ORY94622.1 - 2.7e-27 94.7 13.0 2.7e-27 94.7 13.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.7 ORY94622.1 - 0.0071 16.3 1.3 0.011 15.7 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORY94622.1 - 0.023 14.7 1.2 0.036 14.1 1.2 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORY94622.1 - 0.04 13.3 1.7 0.076 12.4 1.7 1.5 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORY94622.1 - 0.12 12.3 4.7 0.22 11.4 4.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.21 ORY94622.1 - 0.15 11.9 8.9 0.32 10.8 0.4 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-C3HC4_2 PF13923.6 ORY94622.1 - 0.16 11.8 4.8 0.28 11.1 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 ORY94622.1 - 0.44 10.0 3.6 0.35 10.3 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) Acyltransferase PF01553.21 ORY94623.1 - 6.8e-17 61.4 0.0 1.4e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Abhydrolase_1 PF00561.20 ORY94624.1 - 2.1e-10 40.7 0.0 4.8e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY94624.1 - 0.00011 22.9 0.0 0.00018 22.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY94624.1 - 0.00071 18.9 0.0 0.0017 17.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 ORY94624.1 - 0.028 14.0 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Solute_trans_a PF03619.16 ORY94625.1 - 7.5e-43 147.0 9.9 9.4e-43 146.6 9.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha S_4TM PF18159.1 ORY94625.1 - 1.8 7.8 5.1 0.79 9.0 0.3 2.4 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain BTD PF09270.10 ORY94626.1 - 3.7e-23 82.5 0.0 7.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 ORY94626.1 - 6.8e-21 75.5 7.4 1.3e-12 48.6 0.1 3.7 3 1 1 4 4 4 2 LAG1, DNA binding FUSC PF04632.12 ORY94627.1 - 0.012 14.2 2.6 0.02 13.5 2.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribonuc_red_lgC PF02867.15 ORY94628.1 - 8.2e-187 621.9 0.0 1e-186 621.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ORY94628.1 - 3.8e-24 84.5 0.0 7.8e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ORY94628.1 - 2e-07 31.5 0.5 4.8e-07 30.2 0.1 1.9 2 0 0 2 2 2 1 ATP cone domain HSF_DNA-bind PF00447.17 ORY94629.1 - 3.7e-33 114.0 3.1 6.1e-33 113.3 3.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF5517 PF17639.2 ORY94629.1 - 0.00091 19.5 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5517) G-alpha PF00503.20 ORY94630.1 - 1.4e-108 363.2 0.2 1.9e-108 362.8 0.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY94630.1 - 2.3e-13 50.0 2.4 3.6e-09 36.3 0.3 2.8 2 2 1 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY94630.1 - 4e-05 23.1 0.4 0.061 12.7 0.0 2.5 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY94630.1 - 0.0046 17.2 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY94630.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain WAK PF08488.11 ORY94630.1 - 0.082 13.4 0.1 0.26 11.8 0.0 1.8 2 0 0 2 2 2 0 Wall-associated kinase MS_channel PF00924.18 ORY94632.1 - 7.7e-13 48.5 2.2 1.7e-12 47.3 2.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 ORY94632.1 - 4e-05 22.9 0.0 0.00016 21.0 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 ORY94632.1 - 0.00027 20.6 0.0 0.00075 19.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORY94632.1 - 0.0015 18.0 0.1 0.005 16.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORY94632.1 - 0.0033 17.8 0.9 0.023 15.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY94632.1 - 0.0057 16.5 0.1 0.26 11.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair SpoIISA_toxin PF14171.6 ORY94632.1 - 0.39 10.4 2.7 0.36 10.5 0.8 1.8 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system DUF3382 PF11862.8 ORY94632.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3382) Sec15 PF04091.12 ORY94633.1 - 7.3e-54 183.3 0.6 1.3e-53 182.5 0.6 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 ORY94633.1 - 0.0025 17.8 2.6 0.0041 17.2 0.1 2.7 3 0 0 3 3 3 1 Vps51/Vps67 COG5 PF10392.9 ORY94633.1 - 0.041 14.0 4.6 0.032 14.4 2.1 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 COG2 PF06148.11 ORY94633.1 - 0.085 12.9 9.8 0.49 10.5 3.8 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MutS_II PF05188.17 ORY94633.1 - 0.5 10.6 3.5 0.58 10.4 0.9 2.2 2 0 0 2 2 2 0 MutS domain II DUF3807 PF12720.7 ORY94634.1 - 0.0037 17.6 16.7 1.1 9.4 16.7 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) Urm1 PF09138.11 ORY94635.1 - 3.2e-38 130.0 0.1 3.6e-38 129.8 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 ORY94635.1 - 3.7e-05 24.3 0.0 4.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ThiS family ABC_membrane PF00664.23 ORY94636.1 - 1.8e-40 139.4 8.2 3.4e-40 138.4 8.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY94636.1 - 5.3e-36 124.1 0.3 2.5e-35 122.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter MTABC_N PF16185.5 ORY94636.1 - 2.1e-09 37.2 3.8 2.1e-09 37.2 3.8 2.7 3 1 0 3 3 3 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 ORY94636.1 - 6.4e-07 29.0 0.0 1.9e-05 24.2 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY94636.1 - 0.0057 17.1 0.2 0.0057 17.1 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 ORY94636.1 - 0.024 14.4 0.0 0.068 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORY94636.1 - 0.026 14.3 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY94636.1 - 0.034 14.4 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 ORY94636.1 - 0.037 13.8 0.1 0.17 11.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY94636.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 ORY94636.1 - 0.067 13.2 0.1 0.6 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ORY94636.1 - 0.083 12.5 0.3 0.34 10.4 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 ORY94636.1 - 0.13 12.6 0.0 1.3 9.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SIT PF15330.6 ORY94636.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.5 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT PRA1 PF03208.19 ORY94636.1 - 0.52 9.9 8.5 1.2 8.8 1.1 3.4 3 0 0 3 3 3 0 PRA1 family protein PNP_UDP_1 PF01048.20 ORY94637.1 - 1.2e-44 152.3 2.3 1.9e-44 151.6 2.3 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily Helicase_C_3 PF13625.6 ORY94637.1 - 0.026 14.7 0.1 6.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain SinI PF08671.10 ORY94637.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI Sad1_UNC PF07738.13 ORY94638.1 - 4.2e-24 85.0 0.0 8.5e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF3046 PF11248.8 ORY94638.1 - 0.051 13.9 0.2 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3046) ArsA_ATPase PF02374.15 ORY94639.1 - 2.9e-113 378.1 0.9 3.3e-113 377.9 0.9 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 ORY94639.1 - 7.7e-14 52.0 0.3 2.6e-13 50.3 0.1 1.9 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 ORY94639.1 - 8.6e-12 45.2 0.0 1.9e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 ORY94639.1 - 3.5e-06 26.7 0.0 8.7e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 ORY94639.1 - 1.8e-05 24.3 2.5 0.0001 21.8 0.5 2.3 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 ORY94639.1 - 3.7e-05 23.3 0.0 9.1e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 ORY94639.1 - 5.6e-05 22.9 1.4 0.00088 19.0 0.1 2.5 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 ORY94639.1 - 0.0012 18.5 0.1 0.008 15.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORY94639.1 - 0.014 15.2 0.0 0.049 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORY94639.1 - 0.018 14.2 0.0 0.043 13.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 ORY94639.1 - 0.061 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 ORY94639.1 - 0.076 12.2 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 ORY94639.1 - 0.093 12.2 0.0 0.28 10.6 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 ORY94639.1 - 0.11 13.1 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY94639.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRP_SPB PF02978.19 ORY94639.1 - 0.24 12.0 1.9 1.3 9.7 0.3 2.3 2 0 0 2 2 2 0 Signal peptide binding domain Fe_dep_repress PF01325.19 ORY94639.1 - 0.44 10.8 1.8 1.2 9.4 0.1 2.6 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain TRAM_LAG1_CLN8 PF03798.16 ORY94640.1 - 2.5e-40 138.4 29.6 7.7e-40 136.8 22.6 2.1 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 ORY94640.1 - 1.5e-17 63.0 0.6 5.7e-17 61.1 0.6 2.1 1 0 0 1 1 1 1 TRAM1-like protein COX4 PF02936.14 ORY94640.1 - 0.14 12.2 0.8 9.7 6.2 0.1 3.0 3 1 0 3 3 3 0 Cytochrome c oxidase subunit IV EF-hand_4 PF12763.7 ORY94641.1 - 1.1e-33 115.2 0.0 1.1e-12 47.8 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ORY94641.1 - 7.5e-15 53.3 0.4 0.0062 16.0 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 ORY94641.1 - 1.6e-12 47.7 0.4 2.5e-05 24.6 0.0 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY94641.1 - 2.9e-09 36.1 3.1 0.26 11.3 0.0 5.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 ORY94641.1 - 6.2e-09 35.6 0.1 1.9 8.4 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain pair Atg14 PF10186.9 ORY94641.1 - 0.37 9.8 14.8 0.78 8.8 14.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 ORY94641.1 - 0.9 9.3 33.9 0.023 14.5 27.6 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 ORY94641.1 - 1 8.6 23.8 0.17 11.2 20.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FapA PF03961.13 ORY94641.1 - 2.8 6.5 7.7 4.3 5.8 7.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 ORY94641.1 - 2.8 7.1 8.6 6.5 5.9 8.6 1.7 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.8 ORY94641.1 - 8.2 5.1 12.0 14 4.3 12.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter PP2C PF00481.21 ORY94642.1 - 2.1e-40 139.0 0.0 2.6e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY94642.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C GTP_EFTU PF00009.27 ORY94643.1 - 1.8e-55 187.5 0.0 2.8e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY94643.1 - 4.3e-42 142.9 0.0 9e-42 141.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY94643.1 - 1.3e-14 54.3 1.5 1.3e-14 54.3 1.5 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY94643.1 - 0.00054 20.0 0.2 0.012 15.7 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase EAP30 PF04157.16 ORY94644.1 - 1.1e-40 139.4 0.1 1.5e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 ORY94644.1 - 5e-08 32.2 5.2 5e-08 32.2 5.2 2.8 1 1 1 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 ORY94644.1 - 8.8e-06 24.9 10.9 0.0038 16.5 1.1 2.9 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 ORY94644.1 - 0.0039 17.2 10.5 0.49 10.5 0.4 3.3 2 1 1 3 3 3 2 Sec23/Sec24 zinc finger DZR PF12773.7 ORY94644.1 - 0.0088 16.1 7.0 0.017 15.1 0.5 2.3 1 1 1 2 2 2 2 Double zinc ribbon RPA_interact_C PF14768.6 ORY94644.1 - 0.028 15.0 1.3 7.4 7.2 0.6 2.7 2 0 0 2 2 2 0 Replication protein A interacting C-terminal DUF35_N PF12172.8 ORY94644.1 - 0.15 12.0 0.9 0.38 10.7 0.9 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ephrin_rec_like PF07699.13 ORY94644.1 - 0.75 9.6 9.7 4 7.3 1.9 2.3 2 0 0 2 2 2 0 Putative ephrin-receptor like OrfB_Zn_ribbon PF07282.11 ORY94644.1 - 4.4 7.3 8.1 8 6.5 0.6 2.5 1 1 0 2 2 2 0 Putative transposase DNA-binding domain Abhydrolase_1 PF00561.20 ORY94645.1 - 2.7e-14 53.4 0.1 4.1e-14 52.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY94645.1 - 1.6e-07 30.9 0.0 4.1e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY94645.1 - 0.00052 20.7 0.2 0.00096 19.8 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_C78 PF07910.13 ORY94646.1 - 1.1e-56 191.7 0.0 2.1e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 CDC45 PF02724.14 ORY94646.1 - 0.079 11.3 5.6 0.032 12.5 0.3 2.0 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.6 ORY94646.1 - 4.6 7.7 11.5 1.9 8.9 3.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSP70 PF00012.20 ORY94647.1 - 3.1e-267 887.6 11.7 3.6e-267 887.4 11.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY94647.1 - 2.3e-13 49.7 2.7 3.4e-11 42.5 1.4 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 ORY94647.1 - 0.00062 19.6 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 ORY94647.1 - 0.036 14.5 10.3 5 7.6 1.1 4.1 3 1 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.16 ORY94648.1 - 1.6e-69 233.6 0.3 2.5e-69 233.0 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY94648.1 - 7.2e-53 179.6 0.0 9.9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain PMT PF02366.18 ORY94649.1 - 2.5e-88 295.8 20.7 2.5e-88 295.8 20.7 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY94649.1 - 1.5e-61 207.5 12.6 1.5e-61 207.5 12.6 2.6 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY94649.1 - 1.3e-32 113.2 0.4 1.9e-32 112.6 0.4 1.2 1 0 0 1 1 1 1 MIR domain DUF3989 PF13150.6 ORY94649.1 - 0.54 10.0 1.9 13 5.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) FKBP_C PF00254.28 ORY94650.1 - 1.6e-25 89.3 0.0 3.5e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 ORY94650.1 - 1.6e-23 83.3 0.0 1.6e-23 83.3 0.0 2.8 2 1 0 2 2 2 1 Nucleoplasmin-like domain SDA1 PF05285.12 ORY94650.1 - 0.0001 21.8 16.5 0.00014 21.4 16.5 1.2 1 0 0 1 1 1 1 SDA1 DUF4604 PF15377.6 ORY94650.1 - 0.027 14.9 20.5 0.045 14.2 20.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) YL1 PF05764.13 ORY94650.1 - 0.11 12.5 26.4 0.18 11.9 26.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Presenilin PF01080.17 ORY94650.1 - 0.64 8.7 5.0 0.7 8.6 5.0 1.1 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 ORY94650.1 - 1.2 9.4 7.3 1.7 8.9 7.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.12 ORY94650.1 - 8 4.5 29.8 10 4.2 29.8 1.0 1 0 0 1 1 1 0 Nop14-like family eRF1_1 PF03463.15 ORY94651.1 - 3.6e-54 182.2 0.3 6.3e-54 181.4 0.3 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 ORY94651.1 - 6.3e-30 104.2 0.6 9.8e-30 103.6 0.6 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORY94651.1 - 6.8e-25 87.8 0.1 1.9e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 BAR PF03114.18 ORY94652.1 - 0.013 15.2 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 BAR domain DNA_repr_REX1B PF14966.6 ORY94652.1 - 0.016 15.8 0.7 0.032 14.9 0.7 1.5 1 0 0 1 1 1 0 DNA repair REX1-B PHF5 PF03660.14 ORY94653.1 - 6.2e-51 171.0 8.6 6.9e-51 170.8 8.6 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 ORY94653.1 - 0.062 11.2 4.8 0.064 11.1 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 ORY94653.1 - 6.2 7.2 15.0 1.9 8.9 1.2 2.8 1 1 1 2 2 2 0 C1 domain BCDHK_Adom3 PF10436.9 ORY94654.1 - 4.2e-11 42.9 0.2 8e-11 42.0 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase bZIP_1 PF00170.21 ORY94656.1 - 1.8e-11 43.9 9.6 4e-11 42.8 9.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.8 ORY94656.1 - 3.2e-07 30.6 0.7 3.2e-07 30.6 0.7 2.7 2 1 0 2 2 2 1 Aft1 HRA domain bZIP_2 PF07716.15 ORY94656.1 - 4.9e-07 29.7 10.2 4.9e-07 29.7 10.2 2.2 1 1 1 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.8 ORY94656.1 - 7.5e-05 23.1 0.3 7.5e-05 23.1 0.3 4.3 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain ATF7IP_BD PF16788.5 ORY94656.1 - 0.00047 20.3 4.2 0.00047 20.3 4.2 2.7 1 1 1 2 2 2 1 ATF-interacting protein binding domain bZIP_Maf PF03131.17 ORY94656.1 - 0.0022 18.5 5.5 0.0022 18.5 5.5 3.0 2 1 1 3 3 3 1 bZIP Maf transcription factor TolA_bind_tri PF16331.5 ORY94656.1 - 0.44 10.7 14.7 2.9 8.0 3.5 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Macoilin PF09726.9 ORY94656.1 - 3.6 6.0 18.2 5.2 5.5 18.2 1.1 1 0 0 1 1 1 0 Macoilin family Aa_trans PF01490.18 ORY94657.1 - 3.8e-57 193.8 22.9 5.1e-57 193.4 22.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY94657.1 - 0.2 10.7 16.6 0.51 9.3 16.6 1.8 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family ATP19 PF11022.8 ORY94658.1 - 8.8e-22 77.3 0.1 9.9e-22 77.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K DPBB_1 PF03330.18 ORY94659.1 - 3.7e-05 23.9 0.1 6.9e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY94659.1 - 5.2e-05 23.1 0.2 7.8e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Barwin family GRP PF07172.11 ORY94659.1 - 0.034 14.8 0.0 0.051 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF3808 PF10300.9 ORY94660.1 - 1e-57 196.0 2.2 4.6e-57 193.8 2.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 ORY94660.1 - 0.046 13.8 0.0 12 6.3 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C12 PF01088.21 ORY94661.1 - 2.1e-43 148.6 0.4 5.8e-41 140.6 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 R3H PF01424.22 ORY94662.1 - 4.2e-11 42.7 0.1 4.2e-11 42.7 0.1 1.7 2 0 0 2 2 2 1 R3H domain SUIM_assoc PF16619.5 ORY94662.1 - 3.4 7.8 14.7 8 6.6 14.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SUZ PF12752.7 ORY94663.1 - 6.6e-12 46.0 4.8 8.4e-12 45.7 4.8 1.2 1 0 0 1 1 1 1 SUZ domain Ras PF00071.22 ORY94664.1 - 2.7e-59 199.4 0.2 3.6e-59 199.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY94664.1 - 2.1e-36 124.7 0.1 3.4e-36 124.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY94664.1 - 3.7e-15 55.8 0.1 4.7e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY94664.1 - 3.1e-05 23.6 0.1 0.00019 21.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY94664.1 - 4e-05 23.6 0.0 7.6e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY94664.1 - 5.6e-05 22.7 0.0 6.6e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY94664.1 - 0.00017 21.0 0.1 0.00023 20.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY94664.1 - 0.00025 21.0 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY94664.1 - 0.069 12.7 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 ORY94664.1 - 0.076 13.3 0.1 14 5.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY94664.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_S2 PF00318.20 ORY94665.1 - 4e-27 94.9 0.1 5e-13 48.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORY94665.1 - 4.7e-09 37.5 13.0 8.8e-09 36.6 13.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus ANAPC5 PF12862.7 ORY94666.1 - 7.9e-20 70.7 10.6 1.1e-19 70.3 1.8 4.2 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 ORY94666.1 - 0.00013 21.7 4.9 1.5 9.0 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY94666.1 - 0.00023 21.1 2.7 0.71 10.2 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY94666.1 - 0.00046 20.6 8.1 3.3 8.3 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY94666.1 - 0.0069 16.6 6.6 1.1 9.6 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 ORY94666.1 - 0.022 14.5 2.6 1.4 8.6 0.1 3.5 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_14 PF13428.6 ORY94666.1 - 0.033 15.0 9.6 3.7 8.6 0.0 6.1 7 1 0 7 7 7 0 Tetratricopeptide repeat TssR PF17643.1 ORY94666.1 - 0.036 12.0 0.0 0.057 11.4 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssR TPR_9 PF13371.6 ORY94666.1 - 0.043 14.0 0.6 29 4.9 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY94666.1 - 0.17 12.6 0.1 0.17 12.6 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY94666.1 - 0.2 11.9 9.8 8.6 6.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY94666.1 - 4.1 7.8 11.8 22 5.4 0.6 4.8 5 2 1 6 6 6 0 Tetratricopeptide repeat PLATZ PF04640.14 ORY94667.1 - 0.042 14.5 10.8 0.56 10.9 5.7 3.0 1 1 1 2 2 2 0 PLATZ transcription factor Aldo_ket_red PF00248.21 ORY94668.1 - 6.5e-57 193.0 0.0 7.2e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IceA2 PF05862.11 ORY94668.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein PP2C PF00481.21 ORY94669.1 - 4.8e-69 232.9 0.1 5.9e-69 232.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C HAUS6_N PF14661.6 ORY94670.1 - 4.3e-28 98.5 0.9 1.6e-27 96.5 0.9 2.0 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S4 PF00163.19 ORY94670.1 - 0.032 15.1 0.1 0.098 13.6 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L16 PF00252.18 ORY94672.1 - 1.4e-45 154.5 0.1 1.7e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e TetR_C_28 PF17937.1 ORY94673.1 - 2 9.0 10.5 3.8 8.0 0.6 4.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Asp PF00026.23 ORY94674.1 - 8.1e-53 179.9 1.9 1.4e-52 179.1 1.9 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY94674.1 - 2.3e-10 41.0 1.6 1.6e-09 38.3 1.6 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ORY94674.1 - 0.13 12.9 0.0 0.39 11.3 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Na_Ca_ex PF01699.24 ORY94675.1 - 4.4e-22 78.7 28.0 9.3e-17 61.4 11.3 3.2 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 ORY94675.1 - 6.8e-14 52.3 9.0 6.8e-14 52.3 9.0 4.2 4 0 0 4 4 4 2 Inner membrane component domain Kinesin PF00225.23 ORY94676.1 - 2.9e-53 181.0 0.1 3.7e-53 180.6 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY94676.1 - 7.3e-29 100.6 0.7 9.5e-29 100.3 0.1 1.4 2 0 0 2 2 2 1 Microtubule binding PhoH PF02562.16 ORY94676.1 - 0.033 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 ORY94676.1 - 0.05 12.8 0.2 0.081 12.1 0.2 1.3 1 0 0 1 1 1 0 PIF1-like helicase Dymeclin PF09742.9 ORY94677.1 - 8.5e-19 67.4 3.5 9.9e-19 67.2 3.5 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Dymeclin PF09742.9 ORY94678.1 - 3.1e-43 148.2 1.7 3.5e-43 148.0 1.7 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 ORY94678.1 - 4.3e-06 25.2 2.7 5.5e-06 24.8 2.7 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein HisKA_2 PF07568.12 ORY94678.1 - 0.1 12.7 0.3 0.1 12.7 0.3 2.3 2 1 0 2 2 2 0 Histidine kinase FliH PF02108.16 ORY94678.1 - 0.14 12.2 0.7 1.2 9.2 0.2 2.0 2 0 0 2 2 2 0 Flagellar assembly protein FliH LEA_2 PF03168.13 ORY94679.1 - 0.00094 19.7 0.0 0.0026 18.2 0.0 1.8 2 0 0 2 2 2 1 Late embryogenesis abundant protein DUF2897 PF11446.8 ORY94679.1 - 2.2 8.3 4.4 5 7.1 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RNB PF00773.19 ORY94680.1 - 2.1e-98 329.6 0.1 3.2e-98 329.1 0.1 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY94680.1 - 1.3e-20 73.1 0.0 2.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORY94680.1 - 3.6e-15 56.1 0.0 7.7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 ORY94680.1 - 4.4e-06 26.8 0.0 0.00034 20.7 0.0 2.7 2 0 0 2 2 2 1 Cold shock domain Pkinase PF00069.25 ORY94682.1 - 1.1e-78 264.3 0.0 1.3e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94682.1 - 3.9e-40 137.8 0.0 5.2e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY94682.1 - 0.0013 17.6 0.0 0.026 13.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY94682.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY94682.1 - 0.0098 15.8 0.1 0.063 13.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY94682.1 - 0.076 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FERM_N PF09379.10 ORY94682.1 - 0.11 12.4 0.1 3.9 7.5 0.2 2.5 2 0 0 2 2 2 0 FERM N-terminal domain Mod_r PF07200.13 ORY94683.1 - 2.2e-37 128.4 13.0 3.4e-37 127.8 13.0 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RWD PF05773.22 ORY94683.1 - 0.00046 20.4 0.7 0.0016 18.7 0.1 2.2 3 0 0 3 3 3 1 RWD domain MPS2 PF17060.5 ORY94683.1 - 0.0059 15.9 1.6 0.0072 15.6 1.6 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 GrpE PF01025.19 ORY94683.1 - 0.027 14.1 2.9 0.045 13.4 2.9 1.3 1 0 0 1 1 1 0 GrpE UQ_con PF00179.26 ORY94683.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Vps23_core PF09454.10 ORY94683.1 - 0.13 12.3 0.3 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Vps23 core domain Arc_PepC_II PF06847.11 ORY94683.1 - 0.22 12.1 0.1 0.46 11.0 0.1 1.6 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II DUF3573 PF12097.8 ORY94683.1 - 0.35 9.6 0.9 0.5 9.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RNA_pol_Rpb4 PF03874.16 ORY94684.1 - 1.3e-30 106.2 5.0 1.6e-30 106.0 5.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF5063 PF16702.5 ORY94684.1 - 0.0038 17.6 1.8 0.0052 17.2 1.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5063) DUF2757 PF10955.8 ORY94684.1 - 0.019 15.2 0.1 0.038 14.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Cnd1 PF12717.7 ORY94684.1 - 0.075 13.1 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 LPP PF04728.13 ORY94685.1 - 0.052 14.0 0.3 0.052 14.0 0.3 6.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FAM184 PF15665.5 ORY94685.1 - 1.8 8.3 91.7 0.99 9.1 20.8 3.2 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B adh_short PF00106.25 ORY94686.1 - 1.1e-78 263.2 11.0 3.2e-40 137.7 0.7 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY94686.1 - 1.3e-64 218.0 8.5 6.7e-34 117.5 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 ORY94686.1 - 1.5e-31 108.5 0.0 3.7e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 ORY94686.1 - 2.3e-30 105.8 8.7 3.3e-17 63.0 2.0 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 ORY94686.1 - 3.5e-07 30.4 0.0 1.8e-05 24.9 0.0 2.8 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase PglL_A PF15864.5 ORY94686.1 - 1.6 8.6 6.5 14 5.5 0.4 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase Mito_carr PF00153.27 ORY94687.1 - 1.2e-60 201.5 1.2 5.7e-21 74.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY94687.1 - 0.0015 17.7 0.2 1.3 8.1 0.1 2.5 2 1 0 2 2 2 2 Gammaproteobacterial serine protease E1-E2_ATPase PF00122.20 ORY94688.1 - 4.2e-49 166.5 2.3 4.2e-49 166.5 2.3 3.5 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY94688.1 - 1.6e-31 109.5 3.6 1.6e-31 109.5 3.6 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY94688.1 - 1.2e-18 66.9 0.0 2.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY94688.1 - 2e-18 67.5 0.5 2e-17 64.2 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY94688.1 - 9.6e-11 41.2 0.0 3e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY94688.1 - 0.014 15.2 0.2 0.06 13.1 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1749 PF08538.10 ORY94688.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) RNA_pol_Rpb2_6 PF00562.28 ORY94689.1 - 2e-125 418.9 0.0 2e-125 418.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY94689.1 - 4e-59 199.6 0.5 6.1e-59 199.0 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ORY94689.1 - 1e-34 118.8 1.3 2.7e-34 117.4 0.6 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ORY94689.1 - 2.8e-34 118.4 2.2 2.8e-34 118.4 2.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 ORY94689.1 - 1.5e-23 82.9 2.3 2.5e-23 82.1 1.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 ORY94689.1 - 1.1e-21 76.7 0.1 9.9e-21 73.7 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ORY94689.1 - 3.8e-10 40.2 0.5 1.3e-09 38.5 0.5 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CBM_14 PF01607.24 ORY94690.1 - 1.8e-07 31.2 2.4 3e-07 30.5 2.4 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Staph_haemo PF05480.11 ORY94690.1 - 0.35 10.7 1.8 3.2 7.6 0.2 2.6 2 0 0 2 2 2 0 Staphylococcus haemolytic protein DUF3808 PF10300.9 ORY94691.1 - 2.1e-100 336.7 2.3 4e-100 335.8 2.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 ORY94691.1 - 5.3e-07 29.3 9.8 0.011 15.8 0.1 6.5 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY94691.1 - 9.2e-06 25.2 5.6 0.0039 16.6 0.0 2.5 3 0 0 3 3 3 2 MalT-like TPR region TPR_11 PF13414.6 ORY94691.1 - 3e-05 23.6 2.9 0.0043 16.7 0.1 4.1 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 ORY94691.1 - 4.1e-05 23.2 4.5 0.065 13.1 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY94691.1 - 0.0085 16.6 5.9 5.4 7.6 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY94691.1 - 0.0091 16.1 0.2 0.0091 16.1 0.2 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY94691.1 - 0.016 15.2 3.6 11 6.4 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 ORY94691.1 - 0.018 14.7 4.8 0.34 10.6 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 ORY94691.1 - 0.055 14.1 0.1 2.1 9.1 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORY94691.1 - 0.088 12.4 0.0 12 5.5 0.0 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_12 PF13424.6 ORY94691.1 - 0.13 12.6 5.9 13 6.1 0.0 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY94691.1 - 0.25 12.3 2.4 24 6.1 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY94691.1 - 0.41 11.4 2.8 14 6.6 0.1 4.1 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY94691.1 - 9.5 6.2 9.0 3.5 7.6 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ArfGap PF01412.18 ORY94693.1 - 1.1e-36 125.4 0.5 1.7e-36 124.9 0.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5540 PF17694.1 ORY94693.1 - 0.032 14.8 0.0 0.055 14.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5540) Dehydrin PF00257.19 ORY94694.1 - 0.15 12.6 6.3 0.24 11.9 6.3 1.3 1 0 0 1 1 1 0 Dehydrin F-box-like PF12937.7 ORY94695.1 - 1.7e-11 43.8 1.5 3.1e-11 43.0 0.7 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY94695.1 - 3.5e-05 23.5 0.3 0.00014 21.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 ORY94695.1 - 0.017 15.5 0.3 0.64 10.5 0.2 3.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box_5 PF18511.1 ORY94695.1 - 0.13 11.8 0.2 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 F-box Preseq_ALAS PF09029.10 ORY94695.1 - 0.81 10.2 2.5 7.4 7.1 0.1 2.7 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence Yip1 PF04893.17 ORY94697.1 - 4.6e-21 75.3 13.8 8.9e-21 74.4 13.8 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 ORY94697.1 - 0.18 11.5 10.7 0.27 11.0 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF5600 PF18150.1 ORY94698.1 - 2.7e-39 134.0 2.2 5.7e-39 133.0 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 ORY94698.1 - 9.6e-20 70.5 0.0 9.9e-19 67.2 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 ORY94698.1 - 2.6e-13 49.6 0.0 5.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 ORY94698.1 - 1.6e-12 47.8 0.0 1.6e-11 44.6 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ORY94698.1 - 3.1e-07 30.5 0.0 9.6e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY94698.1 - 5.5e-06 26.1 0.0 1.4e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY94698.1 - 9.5e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY94698.1 - 0.00031 20.9 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 ORY94698.1 - 0.00031 20.1 0.1 0.0011 18.4 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORY94698.1 - 0.0071 16.2 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 ORY94698.1 - 0.012 16.1 0.0 0.059 13.8 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair FeoB_N PF02421.18 ORY94698.1 - 0.016 14.7 0.0 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 ORY94698.1 - 0.047 14.0 0.1 3.2 8.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 ORY94698.1 - 0.06 12.8 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY94698.1 - 0.1 12.2 0.2 11 5.5 0.1 2.3 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 ORY94698.1 - 0.17 12.2 0.1 0.89 9.9 0.0 2.1 3 0 0 3 3 2 0 AAA ATPase domain SIR2 PF02146.17 ORY94699.1 - 4.7e-24 85.3 0.3 9.2e-24 84.3 0.0 1.5 2 0 0 2 2 2 1 Sir2 family PhnA_Zn_Ribbon PF08274.12 ORY94699.1 - 0.061 13.3 1.2 0.13 12.3 1.2 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon FYVE_2 PF02318.16 ORY94699.1 - 0.8 9.9 6.1 0.094 12.9 1.0 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger MARVEL PF01284.23 ORY94700.1 - 0.022 14.8 0.9 0.028 14.4 0.9 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF3054 PF11255.8 ORY94700.1 - 0.044 14.3 1.5 0.049 14.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) CPSase_L_D2 PF02786.17 ORY94701.1 - 6.6e-112 372.1 0.3 6.3e-84 280.7 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 ORY94701.1 - 4.1e-49 165.7 0.0 1.1e-48 164.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORY94701.1 - 9.3e-47 159.3 0.0 3.3e-46 157.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 ORY94701.1 - 3.1e-44 150.6 0.0 7.4e-44 149.4 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 ORY94701.1 - 3.7e-42 143.5 0.1 2.7e-41 140.7 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 ORY94701.1 - 6.9e-34 117.2 0.1 1.7e-33 115.9 0.1 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 ORY94701.1 - 8.1e-20 70.8 0.0 3e-19 69.0 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 ORY94701.1 - 6.9e-17 61.7 1.3 9.9e-09 35.0 0.2 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY94701.1 - 4.9e-16 58.8 0.3 5.9e-09 35.7 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORY94701.1 - 8.1e-09 35.3 0.0 0.0011 18.7 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 ORY94701.1 - 1.2e-05 25.5 0.6 0.15 12.1 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 ORY94701.1 - 3.5e-05 23.7 0.1 0.0045 16.8 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 ORY94701.1 - 0.0028 17.5 0.4 0.043 13.6 0.1 3.0 4 0 0 4 4 4 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GSH-S_ATP PF02955.16 ORY94701.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Ion_trans PF00520.31 ORY94702.1 - 1.3e-119 397.9 80.1 1.7e-41 142.1 10.6 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 ORY94702.1 - 0.00044 19.0 5.7 0.00044 19.0 5.7 5.8 5 1 0 5 5 5 2 Polycystin cation channel Staph_haemo PF05480.11 ORY94702.1 - 0.12 12.1 0.3 12 5.8 0.1 2.6 2 0 0 2 2 2 0 Staphylococcus haemolytic protein RseC_MucC PF04246.12 ORY94703.1 - 0.03 14.3 2.2 0.045 13.7 2.2 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Glyco_trans_2_3 PF13632.6 ORY94703.1 - 0.11 12.4 10.4 0.14 12.1 10.4 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 G-patch PF01585.23 ORY94704.1 - 1.3e-08 34.6 0.3 3.9e-08 33.1 0.3 1.8 1 0 0 1 1 1 1 G-patch domain COG4 PF08318.12 ORY94704.1 - 0.0027 16.9 1.4 0.0027 16.9 1.4 2.2 2 0 0 2 2 2 1 COG4 transport protein GldM_N PF12081.8 ORY94705.1 - 0.032 14.3 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 GldM N-terminal domain TFIIA PF03153.13 ORY94705.1 - 2.5 8.0 8.4 3.1 7.7 8.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 7TM_GPCR_Srsx PF10320.9 ORY94706.1 - 0.00091 18.7 21.0 0.0017 17.8 20.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF872 PF05915.12 ORY94706.1 - 0.034 14.3 2.2 0.29 11.3 0.1 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3087 PF11286.8 ORY94707.1 - 1.3 8.5 5.4 0.88 9.0 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DUF1129 PF06570.11 ORY94707.1 - 3.3 7.2 9.9 0.089 12.3 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) UPF0014 PF03649.13 ORY94708.1 - 7e-73 245.0 22.9 8.1e-73 244.7 22.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.22 ORY94708.1 - 0.0045 16.7 8.6 0.0045 16.7 8.6 1.6 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BenE PF03594.13 ORY94708.1 - 0.012 14.5 9.2 0.038 12.8 1.7 2.4 2 0 0 2 2 2 0 Benzoate membrane transport protein ECH_1 PF00378.20 ORY94709.1 - 2.8e-24 85.8 0.0 3.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY94709.1 - 0.00029 20.4 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORY94709.1 - 0.00046 20.2 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Plectin PF00681.20 ORY94709.1 - 0.14 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat Glyco_hydro_3 PF00933.21 ORY94710.1 - 1.8e-84 283.9 0.0 2.3e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 ORY94710.1 - 3.6e-14 53.0 0.3 5e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY94710.1 - 7.1e-12 45.6 0.1 1.6e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY94710.1 - 3.2e-09 36.8 0.2 3.2e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 ORY94710.1 - 8.4e-07 29.1 0.0 1.5e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_9 PF13527.7 ORY94710.1 - 5.5e-06 26.5 0.4 0.0028 17.7 0.0 3.3 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY94710.1 - 4.9e-05 23.2 0.4 0.013 15.4 0.0 3.1 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY94710.1 - 0.0026 17.8 0.3 0.056 13.6 0.0 2.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 ORY94710.1 - 0.056 13.6 0.6 0.3 11.2 0.6 2.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORY94710.1 - 0.077 13.0 0.1 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acyl-CoA_dh_1 PF00441.24 ORY94711.1 - 9.3e-34 116.8 0.7 1.4e-33 116.2 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY94711.1 - 5.7e-23 80.9 0.0 1.2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY94711.1 - 2.4e-14 53.7 1.7 5e-14 52.7 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY94711.1 - 3.8e-14 53.3 0.0 7.2e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ORY94711.1 - 0.02 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PhoLip_ATPase_C PF16212.5 ORY94712.1 - 1.1e-75 254.7 33.9 1.1e-75 254.7 33.9 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY94712.1 - 1.5e-24 85.5 0.1 5.3e-24 83.7 0.1 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY94712.1 - 4.8e-14 52.2 0.1 1.3e-10 41.2 0.0 3.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY94712.1 - 2.7e-10 40.9 0.8 0.0046 17.3 0.0 3.4 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY94712.1 - 5.5e-07 29.3 3.6 1.6e-06 27.8 0.0 2.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY94712.1 - 0.002 17.9 0.6 0.011 15.4 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PrgI PF12666.7 ORY94712.1 - 9.3 7.0 13.8 0.75 10.6 1.1 3.6 3 0 0 3 3 3 0 PrgI family protein Thiolase_N PF00108.23 ORY94713.1 - 2.7e-84 282.6 0.1 5.6e-84 281.6 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY94713.1 - 1.4e-47 160.3 1.9 2.2e-47 159.7 0.7 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY94713.1 - 5.4e-05 22.9 1.0 0.00012 21.8 0.1 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ribosomal_L4 PF00573.22 ORY94714.1 - 1.2e-41 142.5 0.4 2e-41 141.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ORY94714.1 - 5.8e-30 103.2 5.3 3.5e-29 100.7 2.9 2.5 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Kinesin PF00225.23 ORY94715.1 - 5.1e-104 347.8 0.7 5.1e-104 347.8 0.7 3.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORY94715.1 - 9.3e-20 71.1 10.1 9.8e-16 58.0 0.0 4.5 5 1 1 6 6 6 2 Microtubule binding MtrB PF05440.12 ORY94715.1 - 2 8.9 7.9 9.4 6.7 0.1 4.7 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B Pox_A_type_inc PF04508.12 ORY94715.1 - 2.6 8.1 21.6 33 4.6 0.0 9.6 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat DUF2976 PF11190.8 ORY94716.1 - 0.039 13.8 0.2 0.054 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Homeobox_KN PF05920.11 ORY94718.1 - 1.3e-19 69.8 0.9 3.7e-19 68.4 0.9 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY94718.1 - 1.3e-08 34.6 0.8 5.3e-08 32.6 0.8 2.1 1 0 0 1 1 1 1 Homeodomain RhoGAP PF00620.27 ORY94720.1 - 2.2e-07 30.8 0.9 9.4e-07 28.8 0.1 2.5 3 1 0 3 3 3 1 RhoGAP domain Sdh5 PF03937.16 ORY94720.1 - 0.35 10.9 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase Suf PF05843.14 ORY94721.1 - 1.9e-79 267.7 49.2 4.4e-77 260.0 0.0 6.3 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY94721.1 - 2.5e-09 37.1 7.8 0.00057 20.5 0.2 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY94721.1 - 5.6e-06 26.8 7.2 0.0016 18.9 1.4 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat SelB-wing_2 PF09106.11 ORY94721.1 - 0.0053 16.9 0.3 0.041 14.1 0.1 2.5 3 0 0 3 3 3 1 Elongation factor SelB, winged helix TPR_2 PF07719.17 ORY94721.1 - 0.0057 16.7 0.7 1.1 9.5 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY94721.1 - 0.013 15.7 3.2 0.06 13.6 0.3 3.5 4 1 1 5 5 5 0 Tetratricopeptide repeat IMD PF08397.11 ORY94721.1 - 0.043 13.2 4.6 0.1 11.9 4.6 1.6 1 0 0 1 1 1 0 IRSp53/MIM homology domain Rtt106_N PF18215.1 ORY94721.1 - 0.063 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain TPR_16 PF13432.6 ORY94721.1 - 0.074 13.7 3.2 11 6.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY94721.1 - 0.15 12.5 1.2 13 6.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Velvet PF11754.8 ORY94722.1 - 5.1e-32 111.8 0.1 6.1e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Velvet factor adh_short_C2 PF13561.6 ORY94723.1 - 6.4e-53 179.7 0.3 8.3e-53 179.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY94723.1 - 2.7e-41 141.2 0.1 3.4e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY94723.1 - 1.4e-12 47.9 0.1 2e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY94723.1 - 0.0051 17.1 0.1 0.0098 16.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ORY94723.1 - 0.016 15.8 0.1 0.031 14.9 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PTPA PF03095.15 ORY94724.1 - 2.1e-125 418.2 0.1 2.4e-125 418.0 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PseudoU_synth_1 PF01416.20 ORY94725.1 - 4.1e-12 46.5 0.0 9.5e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 ORY94725.1 - 0.078 12.8 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Peptidase_M41 PF01434.18 ORY94726.1 - 2.1e-67 226.7 0.0 3.3e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORY94726.1 - 2.2e-42 144.6 0.0 4.1e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY94726.1 - 2.6e-11 43.2 0.3 5.9e-11 42.0 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ORY94726.1 - 9e-08 32.4 0.1 2.2e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 ORY94726.1 - 0.0026 18.1 0.1 0.054 13.9 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY94726.1 - 0.0033 17.2 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ORY94726.1 - 0.0034 16.6 0.1 0.0057 15.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 ORY94726.1 - 0.0056 17.0 0.1 0.69 10.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY94726.1 - 0.01 15.8 0.0 0.036 14.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 ORY94726.1 - 0.046 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORY94726.1 - 0.093 12.8 0.0 0.29 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ORY94726.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Tim17 PF02466.19 ORY94727.1 - 6.6e-12 45.8 12.9 1.1e-11 45.1 12.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FUN14 PF04930.15 ORY94727.1 - 0.016 15.6 5.6 0.018 15.4 0.7 2.8 3 0 0 3 3 3 0 FUN14 family DUF3493 PF11998.8 ORY94727.1 - 3.1 8.0 5.1 53 4.1 0.1 3.0 2 1 1 3 3 3 0 Low psii accumulation1 / Rep27 Glyco_transf_20 PF00982.21 ORY94728.1 - 3e-167 557.1 0.0 4.4e-167 556.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY94728.1 - 1.6e-54 184.5 0.0 2.3e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY94728.1 - 2.6e-05 24.1 0.0 0.00068 19.4 0.1 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase MBA1 PF07961.11 ORY94728.1 - 0.0092 15.1 0.1 1.7 7.6 0.0 2.3 2 0 0 2 2 2 2 MBA1-like protein Glyco_transf_5 PF08323.11 ORY94728.1 - 0.067 12.9 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain PsbY PF06298.11 ORY94729.1 - 0.051 13.5 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Arf PF00025.21 ORY94730.1 - 2.7e-70 235.4 0.8 3e-70 235.2 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY94730.1 - 5.2e-13 49.3 0.0 7.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY94730.1 - 1.7e-11 43.9 1.3 2.6e-06 26.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY94730.1 - 1.9e-11 43.9 0.0 2.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORY94730.1 - 2.8e-09 36.7 0.0 3.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY94730.1 - 6.2e-09 35.5 0.0 6.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY94730.1 - 3.8e-07 30.2 0.0 8.4e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY94730.1 - 0.00032 20.3 0.0 0.0024 17.5 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 ORY94730.1 - 0.016 15.1 0.4 0.055 13.4 0.1 1.8 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 ORY94730.1 - 0.036 13.1 0.1 0.15 11.1 0.0 1.9 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NIF PF03031.18 ORY94731.1 - 2.4e-55 186.6 0.1 3.5e-55 186.1 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WzyE PF06899.11 ORY94731.1 - 0.24 10.3 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase DUF4820 PF16091.5 ORY94731.1 - 0.44 9.9 5.6 0.63 9.4 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Torus PF16131.5 ORY94732.1 - 4.3e-34 117.5 1.8 4.3e-34 117.5 1.8 2.4 2 1 0 2 2 2 1 Torus domain RRM_1 PF00076.22 ORY94732.1 - 1.7e-07 30.9 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY94732.1 - 0.0002 21.3 0.2 0.00051 20.0 0.2 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 ORY94732.1 - 0.0056 16.7 0.3 0.01 15.9 0.3 1.4 1 0 0 1 1 1 1 Zinc finger domain CG-1 PF03859.16 ORY94732.1 - 7.5 6.4 7.0 13 5.6 0.0 3.1 3 0 0 3 3 3 0 CG-1 domain ChAPs PF09295.10 ORY94733.1 - 1.5e-152 508.2 0.0 2.3e-149 497.7 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 ORY94733.1 - 2.4e-05 24.8 0.7 0.039 14.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY94733.1 - 0.016 15.3 6.2 12 6.3 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY94733.1 - 0.039 14.8 3.3 15 6.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SAPS PF04499.15 ORY94733.1 - 0.3 9.8 11.5 0.43 9.3 11.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TPR_16 PF13432.6 ORY94733.1 - 0.37 11.5 2.3 4.1 8.1 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 ORY94733.1 - 1.2 7.4 10.3 1.7 6.8 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.9 ORY94733.1 - 6 5.9 6.8 11 4.9 6.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_8 PF13181.6 ORY94733.1 - 8.5 6.9 12.5 16 6.0 0.2 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat RRM_1 PF00076.22 ORY94734.1 - 1e-10 41.3 0.1 3e-10 39.8 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY94734.1 - 0.0004 20.0 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY94734.1 - 0.00041 20.2 0.0 0.00061 19.6 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Hyaluronidase_1 PF07212.11 ORY94734.1 - 0.014 14.6 0.5 0.019 14.3 0.5 1.1 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) DCP1 PF06058.13 ORY94735.1 - 2.1e-35 121.2 0.1 3.9e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 ORY94735.1 - 8.9e-05 21.7 0.1 0.00017 20.8 0.1 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus DUF2828 PF11443.8 ORY94735.1 - 0.26 9.3 10.9 0.41 8.7 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CPSF73-100_C PF11718.8 ORY94735.1 - 4 6.9 11.7 1.1 8.7 2.1 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MAP65_ASE1 PF03999.12 ORY94735.1 - 5.2 5.7 36.9 12 4.4 18.8 3.1 3 0 0 3 3 3 0 Microtubule associated protein (MAP65/ASE1 family) PRC2_HTH_1 PF18118.1 ORY94735.1 - 8.7 7.2 13.9 13 6.7 1.4 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain GMC_oxred_N PF00732.19 ORY94736.1 - 7.1e-54 183.2 0.2 1.1e-51 176.0 0.1 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY94736.1 - 2.1e-23 83.5 0.0 5.2e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY94736.1 - 2.1e-08 33.7 3.7 3.1e-05 23.3 1.6 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY94736.1 - 3.2e-06 26.6 0.8 0.0062 15.8 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY94736.1 - 3.3e-05 24.0 1.3 0.00027 21.1 1.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY94736.1 - 0.00012 21.7 8.1 0.0021 17.7 8.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY94736.1 - 0.00049 18.9 0.4 0.0017 17.1 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 ORY94736.1 - 0.0094 15.2 0.4 0.02 14.2 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 ORY94736.1 - 0.069 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ApbA PF02558.16 ORY94736.1 - 0.096 12.3 0.5 0.19 11.4 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SCIFF PF13165.6 ORY94736.1 - 0.1 12.6 0.3 0.23 11.4 0.3 1.6 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF FAD_oxidored PF12831.7 ORY94736.1 - 1.7 7.9 6.5 1.1 8.5 4.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-C2H2 PF00096.26 ORY94737.1 - 0.024 15.1 4.5 0.024 15.1 4.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cwf_Cwc_15 PF04889.12 ORY94737.1 - 0.13 12.0 7.3 0.24 11.1 7.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 ORY94737.1 - 0.21 9.7 9.5 0.31 9.1 9.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2_4 PF13894.6 ORY94737.1 - 0.49 11.4 5.4 1.6 9.8 5.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY94737.1 - 0.59 9.9 2.7 0.75 9.6 0.7 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY94737.1 - 0.81 9.8 4.8 1.5 8.9 4.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Methyltransf_4 PF02390.17 ORY94738.1 - 2.1e-58 196.6 0.0 2.5e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 ORY94738.1 - 0.00014 21.5 0.0 0.00085 18.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY94738.1 - 0.00026 21.6 0.0 0.00047 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY94738.1 - 0.0022 17.8 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY94738.1 - 0.0063 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 ORY94738.1 - 0.0082 16.9 0.0 0.016 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY94738.1 - 0.035 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY94738.1 - 0.082 13.6 0.0 0.23 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 ORY94738.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.6 1 1 1 2 2 2 0 Histone methylation protein DOT1 HEAT PF02985.22 ORY94739.1 - 3.5e-43 141.9 28.4 0.0022 18.1 0.1 14.3 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.6 ORY94739.1 - 2.6e-33 114.3 14.1 5.8e-08 33.0 0.1 6.8 5 2 0 6 6 6 5 HEAT repeats Vac14_Fab1_bd PF12755.7 ORY94739.1 - 1e-11 45.3 2.1 0.016 15.8 0.0 6.5 4 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY94739.1 - 1.7e-08 34.7 6.5 0.0069 16.4 0.1 5.6 1 1 5 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY94739.1 - 3.5e-06 25.9 3.2 0.016 13.8 0.0 3.8 2 1 1 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 ORY94739.1 - 0.00028 21.0 2.2 4.8 7.4 0.1 4.6 3 2 2 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 ORY94739.1 - 0.0014 19.0 19.5 3.5 8.2 0.1 8.8 7 3 4 11 11 11 3 HEAT-like repeat HEAT_PBS PF03130.16 ORY94739.1 - 0.009 16.6 0.7 6 7.9 0.0 4.6 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat API5 PF05918.11 ORY94739.1 - 0.011 14.6 3.8 7.8 5.2 0.0 4.6 5 1 1 6 6 6 0 Apoptosis inhibitory protein 5 (API5) Arm PF00514.23 ORY94739.1 - 0.41 10.8 9.2 56 4.0 0.3 6.1 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat ADH_N PF08240.12 ORY94740.1 - 8.7e-21 73.9 0.2 1.8e-20 72.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY94740.1 - 5.5e-10 39.3 0.9 9.1e-10 38.6 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dabb PF07876.12 ORY94741.1 - 5e-22 78.3 0.0 5.5e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Caudo_TAP PF02413.17 ORY94742.1 - 0.0061 16.7 2.5 0.016 15.3 2.5 1.7 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Cupin_8 PF13621.6 ORY94742.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Cupin-like domain NRBF2 PF08961.10 ORY94742.1 - 7.1 6.2 7.4 25 4.4 0.2 2.4 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator zf-UBR PF02207.20 ORY94743.1 - 1.1e-19 70.4 11.4 1.1e-19 70.4 11.4 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 ORY94743.1 - 1.5e-09 37.5 0.0 6.1e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS FAM60A PF15396.6 ORY94743.1 - 2 8.3 6.3 1.2 9.1 1.6 2.7 3 0 0 3 3 3 0 Protein Family FAM60A PAC4 PF16093.5 ORY94744.1 - 5.5e-16 58.5 0.0 6.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Herpeto_peptide PF14409.6 ORY94744.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon NAD_binding_10 PF13460.6 ORY94746.1 - 0.00034 20.6 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY94746.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_trans_4_2 PF13477.6 ORY94746.1 - 0.081 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Epimerase PF01370.21 ORY94746.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PAC2 PF09754.9 ORY94746.1 - 0.2 11.6 0.2 0.44 10.5 0.1 1.4 1 1 0 1 1 1 0 PAC2 family tRNA-synt_1 PF00133.22 ORY94747.1 - 7.3e-185 615.7 0.0 7.9e-184 612.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY94747.1 - 1.8e-33 115.7 0.0 3.8e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY94747.1 - 2.5e-17 62.7 1.0 6e-09 35.1 0.0 5.0 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORY94747.1 - 7.2e-10 38.7 0.1 6.2e-08 32.4 0.0 2.7 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ORY94747.1 - 0.00027 20.4 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 ORY94747.1 - 0.00039 20.6 4.3 0.00069 19.8 2.8 2.2 1 1 1 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 ORY94747.1 - 0.0042 16.5 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Spt20 PF12090.8 ORY94748.1 - 0.0045 16.6 16.1 0.0045 16.6 16.1 1.7 2 0 0 2 2 2 1 Spt20 family Med15 PF09606.10 ORY94748.1 - 0.016 13.9 20.3 0.022 13.5 20.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF5421 PF17458.2 ORY94748.1 - 0.13 11.6 9.7 0.21 10.9 9.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF2572 PF10833.8 ORY94748.1 - 0.18 11.6 3.8 0.3 10.8 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) ALMT PF11744.8 ORY94748.1 - 1.7 7.4 5.3 2.6 6.8 5.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MPM1 PF17234.2 ORY94748.1 - 6.4 7.0 9.6 14 5.9 9.5 1.6 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TERB2 PF15101.6 ORY94748.1 - 7.2 6.6 11.8 0.89 9.6 7.4 1.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Arm PF00514.23 ORY94749.1 - 2.2e-93 303.8 14.3 5.1e-13 48.6 0.1 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY94749.1 - 3.9e-24 84.7 1.2 4.7e-08 33.4 0.0 6.2 5 1 1 6 6 6 6 HEAT-like repeat Arm_3 PF16186.5 ORY94749.1 - 1.1e-22 79.4 0.1 2.1e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 ORY94749.1 - 8.9e-20 70.9 7.5 4.7e-19 68.6 6.6 2.3 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 ORY94749.1 - 9.9e-20 70.7 0.4 4.2e-07 30.3 0.0 5.8 2 2 5 7 7 7 5 HEAT repeats HEAT PF02985.22 ORY94749.1 - 8.5e-19 66.0 0.1 0.0003 20.8 0.0 6.9 6 0 0 6 6 6 4 HEAT repeat RICTOR_V PF14668.6 ORY94749.1 - 6.8e-06 26.2 0.3 0.073 13.3 0.0 4.9 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 CTNNBL PF08216.11 ORY94749.1 - 1.4e-05 25.2 1.2 8.3 6.6 0.4 5.1 6 0 0 6 6 6 2 Catenin-beta-like, Arm-motif containing nuclear Adaptin_N PF01602.20 ORY94749.1 - 0.00014 20.6 0.0 0.0057 15.3 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 ORY94749.1 - 0.00062 19.9 0.0 16 5.6 0.0 4.3 3 2 2 5 5 5 0 V-ATPase subunit H Arm_2 PF04826.13 ORY94749.1 - 0.001 18.6 0.0 0.58 9.6 0.0 3.2 3 1 1 4 4 4 1 Armadillo-like HEAT_PBS PF03130.16 ORY94749.1 - 0.0014 19.1 1.4 1.1 10.2 0.1 5.0 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 ORY94749.1 - 0.0014 18.6 0.0 7.6 6.6 0.0 4.0 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 ORY94749.1 - 0.023 13.8 0.2 12 4.9 0.0 3.8 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) 2-oxoacid_dh PF00198.23 ORY94750.1 - 1.3e-82 276.8 0.0 1.6e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY94750.1 - 2.4e-16 59.3 0.4 5e-16 58.3 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY94750.1 - 1.4e-14 54.2 0.2 1.4e-14 54.2 0.2 2.2 2 0 0 2 2 2 1 e3 binding domain NCE101 PF11654.8 ORY94751.1 - 6.7e-12 44.9 0.0 8.1e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 Autophagy_act_C PF03987.15 ORY94753.1 - 1.8e-06 28.4 1.9 6.6e-06 26.6 0.3 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Sec16_N PF12935.7 ORY94753.1 - 0.086 13.0 0.8 0.098 12.8 0.8 1.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Cpn10 PF00166.21 ORY94754.1 - 2.6e-31 107.5 0.0 3e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PH PF00169.29 ORY94755.1 - 1.4e-07 32.0 0.1 2.8e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY94755.1 - 0.0075 16.7 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain CDC27 PF09507.10 ORY94756.1 - 0.0019 17.7 15.1 0.0019 17.7 15.1 2.4 2 1 0 2 2 2 1 DNA polymerase subunit Cdc27 RRN3 PF05327.11 ORY94756.1 - 0.04 12.5 6.8 0.071 11.6 6.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Het-C PF07217.11 ORY94756.1 - 5.2 5.5 9.1 0.67 8.4 2.7 1.9 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C zf-CCHC_2 PF13696.6 ORY94757.1 - 0.022 14.6 0.3 0.067 13.0 0.3 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 ORY94757.1 - 0.058 13.5 0.5 0.058 13.5 0.5 2.9 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 ORY94757.1 - 0.5 10.1 8.6 0.9 9.3 0.4 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Syntaxin_2 PF14523.6 ORY94758.1 - 3.9e-29 101.0 6.3 3.9e-29 101.0 6.3 3.1 3 1 0 3 3 3 1 Syntaxin-like protein SNARE PF05739.19 ORY94758.1 - 1e-11 44.6 2.1 3.8e-11 42.8 2.1 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 ORY94758.1 - 4e-07 29.9 16.0 4e-07 29.9 16.0 1.9 2 1 0 2 2 2 1 Syntaxin Mobilization_B PF17511.2 ORY94758.1 - 0.09 13.1 8.1 4.6 7.6 0.0 3.0 2 1 1 3 3 3 0 Mobilization protein B T2SSF PF00482.23 ORY94758.1 - 0.23 11.4 1.1 0.57 10.1 0.1 2.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F SCAB_CC PF16712.5 ORY94758.1 - 0.23 11.3 11.2 0.51 10.2 11.2 1.7 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein LMBR1 PF04791.16 ORY94758.1 - 0.45 9.4 9.4 1.2 8.0 0.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein IFT20 PF14931.6 ORY94758.1 - 0.92 9.7 13.6 1.2 9.4 12.6 1.8 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 YtxH PF12732.7 ORY94758.1 - 4.3 8.0 5.6 3.9 8.1 1.4 2.6 1 1 1 2 2 2 0 YtxH-like protein DUF1664 PF07889.12 ORY94758.1 - 6.9 6.7 10.9 1.6 8.8 0.7 3.1 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 ORY94758.1 - 7.8 6.7 22.4 6.6 6.9 17.7 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) zf-C2H2_2 PF12756.7 ORY94759.1 - 2.8e-36 123.9 8.6 3.3e-23 81.9 2.9 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY94759.1 - 4e-05 23.8 1.9 4e-05 23.8 1.9 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ORY94759.1 - 6.7e-05 23.1 18.7 0.0081 16.6 1.2 5.6 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-BED PF02892.15 ORY94759.1 - 0.0021 18.0 8.9 0.0048 16.9 0.3 4.2 4 0 0 4 4 4 1 BED zinc finger Clr5 PF14420.6 ORY94759.1 - 0.0048 17.1 4.4 0.6 10.4 0.1 3.6 3 1 1 4 4 4 1 Clr5 domain zf-C2H2_4 PF13894.6 ORY94759.1 - 0.0051 17.6 16.1 0.017 15.9 0.5 4.6 5 0 0 5 5 5 1 C2H2-type zinc finger zf-met PF12874.7 ORY94759.1 - 0.0086 16.4 1.4 0.0086 16.4 1.4 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY94759.1 - 0.0092 16.0 1.5 0.038 14.0 1.5 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger FOXP-CC PF16159.5 ORY94759.1 - 0.01 16.4 5.7 6.8 7.4 0.0 4.8 5 0 0 5 5 5 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 ORY94759.1 - 0.011 15.4 0.8 0.011 15.4 0.8 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type PyrI_C PF02748.15 ORY94759.1 - 0.083 12.8 0.0 0.083 12.8 0.0 2.4 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Pneumo_att_G PF05539.11 ORY94759.1 - 0.27 10.8 6.6 0.42 10.2 6.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF1059 PF06348.11 ORY94759.1 - 0.29 11.4 6.3 2.6 8.4 0.1 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF1059) zf-C2H2_7 PF15269.6 ORY94759.1 - 9.1 6.4 6.9 1.5 9.0 1.1 2.5 3 0 0 3 3 3 0 Zinc-finger UPF0086 PF01868.16 ORY94760.1 - 1.5e-26 92.1 0.0 2.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 FAM199X PF15814.5 ORY94760.1 - 0.081 12.0 0.8 0.1 11.6 0.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X TRP PF06011.12 ORY94761.1 - 0.0059 15.4 0.0 0.0081 14.9 0.0 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TMEM154 PF15102.6 ORY94761.1 - 0.036 14.0 0.3 0.82 9.6 0.0 2.4 2 1 0 2 2 2 0 TMEM154 protein family DUF3377 PF11857.8 ORY94761.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Insulin_TMD PF17870.1 ORY94761.1 - 0.11 12.6 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5348 PF17295.2 ORY94761.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) PspB PF06667.12 ORY94761.1 - 0.19 11.8 1.6 0.93 9.6 0.1 2.3 2 0 0 2 2 2 0 Phage shock protein B BatA PF07584.11 ORY94761.1 - 0.35 11.3 2.0 6.4 7.2 0.3 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Gram_pos_anchor PF00746.21 ORY94761.1 - 2.7 8.0 6.5 0.44 10.5 0.4 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif RabGAP-TBC PF00566.18 ORY94763.1 - 1.1e-20 74.3 0.0 1.6e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3151 PF11349.8 ORY94763.1 - 0.0088 16.1 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3151) DUF2890 PF11081.8 ORY94763.1 - 0.66 10.1 4.5 1.2 9.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) PTEN_C2 PF10409.9 ORY94764.1 - 2.8e-10 40.1 0.1 4e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase3 PF13350.6 ORY94764.1 - 2.6e-05 24.3 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY94764.1 - 0.0001 22.0 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY94764.1 - 0.00018 21.3 0.0 0.00039 20.2 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY94764.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Pkr1 PF08636.10 ORY94765.1 - 5.7e-23 80.8 0.8 6.3e-23 80.7 0.8 1.0 1 0 0 1 1 1 1 ER protein Pkr1 ApoO PF09769.9 ORY94765.1 - 0.11 12.4 1.4 0.13 12.2 1.0 1.5 1 1 0 1 1 1 0 Apolipoprotein O zf-H2C2_2 PF13465.6 ORY94766.1 - 6.7e-25 86.4 19.6 1.1e-08 35.0 0.8 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORY94766.1 - 2.5e-23 81.1 20.7 8e-06 26.0 0.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY94766.1 - 1.7e-13 50.1 19.2 0.0025 18.5 0.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY94766.1 - 2.3e-07 30.9 2.0 0.19 12.1 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY94766.1 - 1.4e-06 28.9 1.8 1.4 9.6 0.1 4.2 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY94766.1 - 3e-05 24.2 8.8 0.002 18.4 1.3 2.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY94766.1 - 0.0031 17.5 11.0 0.46 10.5 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY94766.1 - 0.0057 16.9 7.1 0.37 11.1 0.1 3.8 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY94766.1 - 0.0099 16.2 6.8 35 5.0 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORY94766.1 - 0.017 15.0 5.4 1.7 8.7 0.1 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.5 ORY94766.1 - 0.023 14.9 3.1 3.7 7.7 0.2 2.9 2 1 1 3 3 3 0 Aberrant zinc-finger zf_ZIC PF18366.1 ORY94766.1 - 0.044 13.9 3.8 10 6.3 0.0 3.8 4 0 0 4 4 4 0 Zic proteins zinc finger domain DUF4729 PF15866.5 ORY94766.1 - 0.21 10.9 0.1 0.21 10.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4729) zf-TRAF PF02176.18 ORY94766.1 - 0.29 11.8 10.3 3 8.6 1.2 3.2 1 1 1 3 3 3 0 TRAF-type zinc finger zf-CGNR PF11706.8 ORY94766.1 - 1.2 9.0 10.6 8.5 6.3 0.0 3.6 3 1 1 4 4 4 0 CGNR zinc finger zf-DNA_Pol PF08996.10 ORY94766.1 - 2.3 7.9 6.5 11 5.7 6.5 1.8 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger CrgA PF06781.12 ORY94767.1 - 0.11 12.5 0.7 0.75 9.9 0.1 2.7 2 0 0 2 2 2 0 Cell division protein CrgA TMEM100 PF16311.5 ORY94767.1 - 0.14 11.8 0.6 5.3 6.6 0.1 2.7 2 1 0 2 2 2 0 Transmembrane protein 100 Arf PF00025.21 ORY94768.1 - 2.8e-66 222.3 0.0 3.2e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY94768.1 - 5.7e-10 38.9 0.0 7.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORY94768.1 - 6.1e-09 35.5 0.0 2.2e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 ORY94768.1 - 1.8e-07 31.4 0.0 4.2e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY94768.1 - 6.1e-07 29.5 0.0 1.2e-06 28.6 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 ORY94768.1 - 1.7e-06 27.7 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY94768.1 - 8.5e-06 25.3 0.0 9.7e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 ORY94768.1 - 0.026 14.3 0.0 0.13 12.0 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ORY94768.1 - 0.19 11.3 0.0 7.9 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MIF4G PF02854.19 ORY94770.1 - 2.9e-63 213.4 10.7 4.7e-38 130.9 0.3 3.7 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 ORY94770.1 - 4.3e-40 137.6 14.0 4.3e-40 137.6 14.0 3.6 4 1 0 4 4 4 1 Up-frameshift suppressor 2 Ead_Ea22 PF13935.6 ORY94771.1 - 0.025 15.2 0.8 0.058 14.1 0.8 1.6 1 0 0 1 1 1 0 Ead/Ea22-like protein Beta_protein PF14350.6 ORY94771.1 - 0.12 11.7 1.1 0.17 11.3 0.4 1.5 2 0 0 2 2 2 0 Beta protein Cyt-b5 PF00173.28 ORY94772.1 - 1.6e-10 41.0 0.2 2.7e-10 40.3 0.2 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SnoaL_4 PF13577.6 ORY94772.1 - 0.072 13.2 0.3 0.14 12.2 0.2 1.5 1 1 0 1 1 1 0 SnoaL-like domain PUF PF00806.19 ORY94773.1 - 6e-64 208.3 6.5 1.2e-07 31.0 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 ORY94773.1 - 0.024 15.0 0.2 3.9 7.8 0.1 3.7 2 1 2 4 4 4 0 CPL (NUC119) domain HECT PF00632.25 ORY94774.1 - 7.9e-50 170.1 0.0 3.1e-29 102.5 0.0 2.5 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 ORY94774.1 - 4.9e-15 55.5 0.9 2.7e-14 53.1 0.9 2.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF5109 PF17134.4 ORY94774.1 - 0.18 11.7 0.1 0.54 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5109) DUF2013 PF09431.10 ORY94775.1 - 7.1e-46 155.8 4.4 7.1e-46 155.8 4.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) SR-25 PF10500.9 ORY94775.1 - 3.5 7.2 14.8 6 6.4 14.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FA_hydroxylase PF04116.13 ORY94776.1 - 9.7e-23 81.0 13.3 9.7e-23 81.0 13.3 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily BTG PF07742.12 ORY94777.1 - 8.1e-33 112.7 0.0 9.2e-33 112.6 0.0 1.0 1 0 0 1 1 1 1 BTG family Ribonuc_P_40 PF08584.11 ORY94778.1 - 3e-53 181.0 0.1 5.1e-53 180.2 0.1 1.3 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit DUF4003 PF13170.6 ORY94778.1 - 0.15 11.4 0.4 0.26 10.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) RRM_1 PF00076.22 ORY94779.1 - 1.5e-15 56.7 0.9 3e-11 43.0 0.2 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY94779.1 - 0.012 15.6 1.3 1.5 8.8 0.2 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Romo1 PF10247.9 ORY94780.1 - 0.0035 17.7 1.0 0.093 13.1 0.2 2.3 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 SpoVAB PF13782.6 ORY94780.1 - 0.076 13.3 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AB Tim17 PF02466.19 ORY94780.1 - 0.096 13.1 0.6 0.44 10.9 0.1 2.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family FH2 PF02181.23 ORY94780.1 - 0.13 11.4 2.2 0.23 10.5 1.9 1.5 2 0 0 2 2 2 0 Formin Homology 2 Domain TniQ PF06527.11 ORY94780.1 - 0.17 12.6 0.8 0.31 11.8 0.8 1.3 1 0 0 1 1 1 0 TniQ VHS PF00790.19 ORY94781.1 - 1.2e-30 106.3 0.0 2.4e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 ORY94781.1 - 5.1e-17 61.2 0.1 9.7e-17 60.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY94781.1 - 3.3e-15 55.7 0.1 6.4e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY94781.1 - 1.5e-12 47.0 0.2 3.1e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 ORY94781.1 - 5.3e-12 45.9 0.5 1.7e-11 44.3 0.5 1.9 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 ORY94781.1 - 0.0064 16.3 4.6 0.0064 16.3 4.6 3.1 5 0 0 5 5 5 1 Ubiquitin interaction motif DLIC PF05783.11 ORY94781.1 - 0.23 10.2 2.1 0.5 9.1 2.1 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 ORY94782.1 - 2.8e-27 94.3 0.0 2.5e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.22 ORY94782.1 - 2.9 7.0 5.2 6.5 5.9 0.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter 4HBT_3 PF13622.6 ORY94784.1 - 4e-64 217.2 0.1 4.9e-64 217.0 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORY94784.1 - 3.7e-39 133.6 0.1 3e-28 98.3 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase VTC PF09359.10 ORY94785.1 - 1.9e-84 283.3 0.2 3.1e-84 282.6 0.2 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 ORY94785.1 - 4e-12 46.4 1.8 8.8e-12 45.3 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 ORY94785.1 - 1.2e-06 28.8 5.0 7.4e-06 26.1 0.1 2.8 3 0 0 3 3 3 1 SPX domain Prefoldin PF02996.17 ORY94785.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit YtpI PF14007.6 ORY94785.1 - 0.076 13.2 1.4 0.26 11.4 0.5 2.1 2 0 0 2 2 2 0 YtpI-like protein DUF4326 PF14216.6 ORY94785.1 - 0.13 13.0 0.1 0.47 11.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4326) DUF1029 PF06269.12 ORY94785.1 - 0.95 9.6 3.5 0.38 10.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) Lipase_3 PF01764.25 ORY94787.1 - 2.6e-15 56.5 0.0 4.1e-14 52.6 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) NDT80_PhoG PF05224.12 ORY94787.1 - 0.091 13.0 4.8 1.5 9.0 0.0 3.1 3 0 0 3 3 3 0 NDT80 / PhoG like DNA-binding family VTC PF09359.10 ORY94789.1 - 5.8e-84 281.7 0.0 1.1e-83 280.9 0.0 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 ORY94789.1 - 5.5e-14 52.4 3.3 1.1e-13 51.4 3.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 ORY94789.1 - 1.1e-11 45.4 9.9 1.8e-05 24.9 0.0 4.1 2 1 2 4 4 4 4 SPX domain Pkinase PF00069.25 ORY94790.1 - 6.9e-37 127.2 0.0 6.5e-11 42.1 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94790.1 - 1.8e-17 63.5 0.0 9.6e-11 41.4 0.0 3.4 2 2 0 2 2 2 2 Protein tyrosine kinase Nexin_C PF08628.12 ORY94790.1 - 0.044 14.4 0.1 0.33 11.6 0.0 2.4 3 0 0 3 3 3 0 Sorting nexin C terminal Kinase-like PF14531.6 ORY94790.1 - 0.12 11.6 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Kinase-like DUF848 PF05852.11 ORY94790.1 - 0.13 12.4 2.3 0.29 11.2 2.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Na_sulph_symp PF00939.19 ORY94791.1 - 2.1e-31 109.5 30.5 3e-31 109.0 30.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 ORY94791.1 - 1.9e-28 100.5 17.9 4.4e-12 46.6 2.0 3.1 1 1 2 3 3 3 3 SPX domain CitMHS PF03600.16 ORY94791.1 - 1.1e-21 77.3 52.0 8.3e-19 67.9 26.8 2.7 1 1 2 3 3 3 2 Citrate transporter NCBP3 PF10309.9 ORY94793.1 - 9.2e-05 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 ORY94793.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain Cytochrom_C PF00034.21 ORY94794.1 - 7.6e-14 52.6 0.1 1.2e-13 52.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORY94794.1 - 2.7e-09 37.2 4.1 2e-08 34.4 4.1 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORY94794.1 - 0.0027 17.4 1.2 0.029 14.1 1.2 2.2 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 ORY94794.1 - 0.05 13.2 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 CCP_MauG PF03150.14 ORY94794.1 - 0.059 14.0 0.0 0.064 13.9 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Mito_carr PF00153.27 ORY94795.1 - 2.6e-67 222.8 1.1 6.5e-21 74.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY94795.1 - 1.4e-05 24.4 0.8 0.12 11.6 0.3 3.3 2 1 1 3 3 3 2 Gammaproteobacterial serine protease SQS_PSY PF00494.19 ORY94796.1 - 9.3e-37 126.9 0.0 1.4e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4046 PF13255.6 ORY94796.1 - 0.068 13.7 0.0 11 6.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) IES5 PF17335.2 ORY94796.1 - 0.12 12.7 0.4 0.47 10.7 0.1 2.1 2 1 1 3 3 3 0 Ino80 complex subunit 5 Pkinase PF00069.25 ORY94797.1 - 4e-71 239.5 0.0 5.2e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94797.1 - 4.2e-36 124.5 0.0 5.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY94797.1 - 0.00035 20.0 0.0 0.00065 19.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY94797.1 - 0.091 12.7 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_129 PF11308.8 ORY94797.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 TFIIA PF03153.13 ORY94798.1 - 0.023 14.7 15.2 0.028 14.5 15.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec10 PF07393.11 ORY94798.1 - 0.024 13.1 1.3 0.027 12.9 1.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 DLIC PF05783.11 ORY94798.1 - 0.066 12.0 2.7 0.079 11.8 2.7 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Presenilin PF01080.17 ORY94798.1 - 0.09 11.5 5.3 0.1 11.3 5.3 1.2 1 0 0 1 1 1 0 Presenilin Mucin15 PF15672.5 ORY94798.1 - 0.13 11.7 6.3 0.16 11.5 6.3 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Mitofilin PF09731.9 ORY94798.1 - 0.13 11.0 7.2 0.14 10.9 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CEND1 PF15677.5 ORY94798.1 - 0.26 11.8 10.4 0.36 11.4 10.4 1.2 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Roughex PF06020.11 ORY94798.1 - 0.73 8.9 7.0 0.83 8.7 7.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TMEM214 PF10151.9 ORY94798.1 - 2.4 6.5 7.8 2.9 6.2 7.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4407 PF14362.6 ORY94798.1 - 2.8 7.2 6.9 3.7 6.8 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SOG2 PF10428.9 ORY94798.1 - 5.4 6.1 16.2 7.5 5.6 16.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 ORY94798.1 - 6.4 5.3 13.0 6.6 5.3 13.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 ORY94798.1 - 8.3 5.9 11.2 11 5.5 11.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Arrestin_N PF00339.29 ORY94800.1 - 3.5e-10 40.1 0.0 3.1e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY94800.1 - 2.7e-06 27.9 0.2 1.3e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DciA PF05258.12 ORY94800.1 - 0.029 14.8 0.0 0.11 12.9 0.0 1.9 1 1 1 2 2 2 0 Dna[CI] antecedent, DciA MFS_2 PF13347.6 ORY94801.1 - 7.5e-08 31.3 17.2 7.5e-08 31.3 17.2 2.1 2 1 0 2 2 2 1 MFS/sugar transport protein AAA_lid_7 PF17867.1 ORY94802.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Midasin AAA lid domain LIM_bind PF01803.16 ORY94805.1 - 3.1e-44 151.3 0.3 3.1e-44 151.3 0.3 5.6 3 2 0 3 3 3 1 LIM-domain binding protein LIM_bind PF01803.16 ORY94806.1 - 9.5e-09 35.1 1.1 2.5e-05 23.9 1.1 2.7 1 1 0 1 1 1 1 LIM-domain binding protein Pkinase PF00069.25 ORY94807.1 - 5.5e-75 252.1 0.0 6.4e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94807.1 - 2e-30 106.0 0.0 2.7e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY94807.1 - 0.0012 18.3 0.2 0.0054 16.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 ORY94807.1 - 0.029 14.3 0.3 0.048 13.6 0.3 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY94807.1 - 0.038 12.9 0.0 0.95 8.3 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY94807.1 - 0.086 11.9 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_35 PF01301.19 ORY94808.1 - 2.3e-80 270.6 2.7 3.9e-80 269.8 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ORY94808.1 - 3.7e-52 175.7 3.9 2.8e-30 105.2 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ORY94808.1 - 8.5e-25 87.6 0.6 1.5e-24 86.8 0.6 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ORY94808.1 - 7.7e-24 83.1 0.1 2.7e-23 81.3 0.1 2.0 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 ORY94808.1 - 1.6e-07 31.0 0.5 2e-06 27.4 0.4 2.3 1 1 0 1 1 1 1 Beta-galactosidase Mito_carr PF00153.27 ORY94809.1 - 1.9e-60 200.8 1.9 5.2e-21 74.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein HSCB_C PF07743.13 ORY94810.1 - 2e-19 69.9 8.8 2e-19 69.9 8.8 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 ORY94810.1 - 2.2e-05 24.5 1.0 2.2e-05 24.5 1.0 1.8 2 0 0 2 2 2 1 DnaJ domain UPF0547 PF10571.9 ORY94810.1 - 0.012 15.7 1.9 0.021 14.9 1.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 cwf21 PF08312.12 ORY94810.1 - 0.2 11.9 4.8 0.43 10.8 4.8 1.6 1 0 0 1 1 1 0 cwf21 domain Methyltransf_13 PF08421.11 ORY94810.1 - 1.1 9.6 4.8 9.8 6.5 0.5 2.8 3 0 0 3 3 3 0 Putative zinc binding domain Ctr PF04145.15 ORY94811.1 - 9.7e-37 126.9 1.6 1.1e-36 126.6 1.6 1.0 1 0 0 1 1 1 1 Ctr copper transporter family WD40 PF00400.32 ORY94812.1 - 1.9e-35 120.2 21.6 1.8e-06 28.6 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 ORY94812.1 - 8.4e-08 31.3 11.0 0.011 14.4 0.2 5.1 5 0 0 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY94812.1 - 1.2e-05 25.5 0.0 5.8 7.3 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY94812.1 - 0.0013 18.1 0.0 2.4 7.4 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain UPF0542 PF15086.6 ORY94812.1 - 0.019 14.9 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF2890 PF11081.8 ORY94812.1 - 0.06 13.5 4.5 6.4 6.9 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2890) UPF0449 PF15136.6 ORY94812.1 - 0.21 12.1 9.2 0.019 15.4 4.5 1.8 2 1 0 2 2 1 0 Uncharacterised protein family UPF0449 YabA PF06156.13 ORY94812.1 - 1.3 9.7 9.0 0.22 12.2 4.3 2.1 2 1 0 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 ORY94812.1 - 1.7 7.9 15.9 0.046 13.0 6.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 ORY94812.1 - 1.7 8.7 9.9 0.15 12.1 5.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 ORY94812.1 - 2.2 8.7 12.6 0.12 12.8 6.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.9 ORY94812.1 - 5.8 7.1 12.7 1.5 9.1 8.2 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 LETM1 PF07766.13 ORY94813.1 - 4.8e-107 357.3 1.9 4.8e-107 357.3 1.9 2.4 3 0 0 3 3 3 1 LETM1-like protein SAP PF02037.27 ORY94813.1 - 0.014 15.1 0.0 0.17 11.7 0.0 2.7 2 0 0 2 2 2 0 SAP domain DUF3232 PF11554.8 ORY94813.1 - 0.3 11.4 3.3 0.42 11.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) HycH PF07450.11 ORY94813.1 - 0.47 10.8 2.3 0.8 10.1 0.3 2.6 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH RRN3 PF05327.11 ORY94814.1 - 3.2 6.2 9.9 3.6 6.0 9.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 ORY94814.1 - 3.8 5.6 17.2 4.4 5.4 17.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORY94814.1 - 4.2 5.5 12.3 4.8 5.4 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 ORY94814.1 - 7.2 5.9 18.9 8.3 5.7 18.9 1.1 1 0 0 1 1 1 0 SDA1 zf-C2H2 PF00096.26 ORY94817.1 - 5.8e-08 32.8 17.3 7.9e-05 22.9 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY94817.1 - 6.5e-05 23.1 0.8 0.00063 20.0 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORY94817.1 - 0.00026 21.3 2.7 0.00026 21.3 2.7 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY94817.1 - 0.0018 18.2 0.5 0.0047 16.9 0.5 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY94817.1 - 0.0042 17.8 1.1 0.0042 17.8 1.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf_Hakai PF18408.1 ORY94817.1 - 0.0049 16.6 0.5 0.017 14.8 0.5 1.9 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain zf-met PF12874.7 ORY94817.1 - 0.012 16.0 3.6 0.028 14.8 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORY94817.1 - 0.021 15.5 0.2 0.021 15.5 0.2 4.1 2 1 2 4 4 4 0 FOXP coiled-coil domain zf_ZIC PF18366.1 ORY94817.1 - 0.092 12.9 1.0 0.4 10.8 0.0 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain DLH PF01738.18 ORY94817.1 - 0.097 12.2 0.0 0.097 12.2 0.0 2.0 3 0 0 3 3 3 0 Dienelactone hydrolase family AMP-binding PF00501.28 ORY94818.1 - 4e-80 269.5 0.0 5.2e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY94818.1 - 7.5e-09 36.4 0.1 1.7e-08 35.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ORY94819.1 - 1.4e-73 247.9 0.0 1.9e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY94819.1 - 2.1e-06 28.6 0.0 4.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2853 PF11015.8 ORY94819.1 - 0.026 15.2 0.1 0.056 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) Asparaginase_2 PF01112.18 ORY94820.1 - 7.1e-48 163.2 4.2 1.1e-47 162.6 4.2 1.3 1 0 0 1 1 1 1 Asparaginase NIF PF03031.18 ORY94821.1 - 1.3e-38 132.2 0.0 1.6e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORY94821.1 - 0.0017 18.8 0.4 0.017 15.5 0.0 2.3 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 ORY94821.1 - 0.22 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) FMN_red PF03358.15 ORY94822.1 - 7.5e-13 48.5 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY94822.1 - 5.9e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 ORY94822.1 - 0.00035 20.8 0.3 0.018 15.3 0.0 2.9 1 1 1 2 2 2 1 Flavodoxin DUF2151 PF10221.9 ORY94822.1 - 3.5 6.1 7.7 5 5.6 7.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator NPR3 PF03666.13 ORY94822.1 - 8.7 5.0 8.0 12 4.5 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FMN_red PF03358.15 ORY94823.1 - 5.6e-13 48.9 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY94823.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 ORY94823.1 - 0.068 13.4 0.0 1.4 9.1 0.0 2.4 1 1 0 1 1 1 0 Flavodoxin 4HBT_3 PF13622.6 ORY94824.1 - 2e-20 74.1 0.0 2.7e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.16 ORY94826.1 - 1.4e-51 175.6 24.7 1.4e-51 175.6 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY94826.1 - 2.8e-11 43.0 24.5 1.5e-09 37.3 7.9 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ORY94826.1 - 5.7e-09 35.0 1.7 5.7e-09 35.0 1.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORY94826.1 - 0.00021 19.7 2.0 0.00021 19.7 2.0 2.3 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_5 PF05631.14 ORY94826.1 - 0.0022 17.0 2.5 0.078 11.9 0.1 2.6 3 0 0 3 3 3 2 Sugar-tranasporters, 12 TM Proteasom_PSMB PF10508.9 ORY94827.1 - 2.6e-64 217.5 0.0 3.2e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 ORY94827.1 - 0.00015 21.9 0.0 6 7.2 0.0 4.0 3 1 1 4 4 4 3 Rapamycin-insensitive companion of mTOR, domain 5 DUF3636 PF12331.8 ORY94827.1 - 0.0016 18.3 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3636) HEAT_2 PF13646.6 ORY94827.1 - 0.002 18.5 0.2 6.3 7.3 0.0 5.0 3 2 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.20 ORY94827.1 - 0.021 13.4 0.6 0.55 8.7 0.1 2.6 1 1 1 2 2 2 0 Adaptin N terminal region RICTOR_M PF14666.6 ORY94827.1 - 0.043 13.6 0.1 1.2 9.0 0.0 3.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain V-ATPase_H_N PF03224.14 ORY94827.1 - 0.079 12.2 0.1 2.7 7.2 0.0 2.5 1 1 0 2 2 2 0 V-ATPase subunit H Tox-MPTase4 PF15640.6 ORY94827.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 4 RTP1_C1 PF10363.9 ORY94827.1 - 0.18 12.0 1.3 8.1 6.7 0.1 3.0 2 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 ORY94827.1 - 0.35 11.3 3.2 79 3.9 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Acetyltransf_1 PF00583.25 ORY94828.1 - 3.6e-11 43.3 0.1 4.5e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY94828.1 - 4.2e-06 27.1 0.0 5.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY94828.1 - 6.8e-05 22.8 0.0 8.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY94828.1 - 0.00064 19.6 0.0 0.00093 19.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Gln-synt_C PF00120.24 ORY94829.1 - 1.4e-20 73.6 0.0 1.8e-16 60.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ORY94829.1 - 1.9e-12 46.7 0.0 3.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain O-FucT PF10250.9 ORY94830.1 - 0.024 14.4 0.0 0.59 9.8 0.0 2.4 2 1 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase tRNA-synt_1d PF00750.19 ORY94833.1 - 3.3e-105 351.9 2.6 4.3e-105 351.5 2.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY94833.1 - 1e-20 74.1 0.0 2.5e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ORY94833.1 - 1.6e-10 41.4 0.4 4.9e-10 39.9 0.1 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Adaptin_N PF01602.20 ORY94834.1 - 3.3e-128 428.5 7.5 4.5e-128 428.1 7.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 ORY94834.1 - 1.2e-33 115.6 0.0 4.6e-33 113.8 0.0 2.0 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 ORY94834.1 - 6.7e-12 45.7 0.8 6.7e-12 45.7 0.8 2.0 1 1 1 2 2 2 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 ORY94834.1 - 0.13 12.5 0.3 0.66 10.2 0.2 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 KxDL PF10241.9 ORY94835.1 - 4.9e-20 71.6 4.4 7.1e-20 71.1 4.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF3584 PF12128.8 ORY94835.1 - 0.0016 16.1 2.5 0.0018 15.9 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Sec8_exocyst PF04048.14 ORY94835.1 - 0.018 14.9 1.9 0.024 14.5 1.9 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain BLOC1_2 PF10046.9 ORY94835.1 - 0.039 14.2 0.4 0.056 13.8 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1704 PF08014.11 ORY94835.1 - 0.049 12.7 2.0 0.054 12.5 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) DUF2130 PF09903.9 ORY94835.1 - 0.056 12.7 0.7 0.062 12.5 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Snapin_Pallidin PF14712.6 ORY94835.1 - 0.24 11.8 3.4 0.36 11.3 3.4 1.3 1 0 0 1 1 1 0 Snapin/Pallidin YlqD PF11068.8 ORY94835.1 - 0.31 11.4 3.0 0.36 11.2 3.0 1.2 1 0 0 1 1 1 0 YlqD protein F-box-like PF12937.7 ORY94836.1 - 1.5e-09 37.6 0.1 5e-09 35.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY94836.1 - 1.9e-05 24.9 4.3 0.35 11.4 0.1 5.5 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY94836.1 - 2.8e-05 23.9 0.4 0.00038 20.2 0.0 2.9 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 ORY94836.1 - 0.0086 16.1 6.3 3.5 7.9 0.0 5.4 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.6 ORY94836.1 - 0.058 13.2 6.3 1.5 8.6 0.3 3.7 2 2 1 3 3 3 0 Leucine rich repeat DUF1699 PF08004.11 ORY94836.1 - 0.069 12.8 0.1 0.71 9.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) CMD PF02627.20 ORY94837.1 - 0.02 14.9 0.0 0.083 13.0 0.0 2.0 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family NOG1_N PF17835.1 ORY94837.1 - 0.12 12.3 0.0 8.3 6.3 0.0 2.5 2 1 1 3 3 3 0 NOG1 N-terminal helical domain CNOT1_TTP_bind PF16417.5 ORY94837.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain adh_short PF00106.25 ORY94838.1 - 9.4e-34 116.6 0.0 1.3e-32 112.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY94838.1 - 9.9e-20 71.1 0.0 1.2e-18 67.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY94838.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY94838.1 - 0.00016 21.2 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY94838.1 - 0.00098 18.6 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ORY94838.1 - 0.0026 17.1 0.0 0.0055 16.0 0.0 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SASA PF03629.18 ORY94839.1 - 2.2e-53 181.2 0.1 3.2e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Csc2 PF18320.1 ORY94839.1 - 0.068 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Csc2 Crispr G-alpha PF00503.20 ORY94840.1 - 6.1e-100 334.8 0.1 7.4e-100 334.5 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY94840.1 - 3.8e-10 39.5 0.1 4.1e-09 36.1 0.1 2.5 3 0 0 3 3 3 1 ADP-ribosylation factor family Amidase PF01425.21 ORY94842.1 - 1.4e-91 307.8 0.0 2e-91 307.3 0.0 1.2 1 0 0 1 1 1 1 Amidase HSP70 PF00012.20 ORY94843.1 - 4.8e-258 857.3 10.4 5.4e-258 857.1 10.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY94843.1 - 2.1e-16 59.7 0.2 5.4e-15 55.0 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 ORY94843.1 - 0.0028 18.0 4.4 1.2 9.5 0.0 3.8 3 2 0 3 3 3 1 Cell division protein FtsA DDR PF08841.10 ORY94843.1 - 0.0082 15.2 0.2 0.034 13.2 0.1 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain TF_AP-2 PF03299.14 ORY94843.1 - 0.11 12.5 2.5 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Transcription factor AP-2 Cas_Cas4 PF01930.17 ORY94843.1 - 0.11 12.6 1.1 0.32 11.1 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF83 Pex19 PF04614.12 ORY94843.1 - 4.4 7.0 8.7 0.98 9.1 4.6 1.9 2 0 0 2 2 2 0 Pex19 protein family DUF4795 PF16043.5 ORY94843.1 - 6.3 6.3 10.6 0.47 10.0 4.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) UPF0242 PF06785.11 ORY94843.1 - 7.6 6.6 10.6 1.1 9.3 5.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RabGAP-TBC PF00566.18 ORY94844.1 - 5.5e-57 192.9 3.1 5.6e-57 192.8 0.0 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PI_PP_I PF18363.1 ORY94844.1 - 9.5 6.5 13.0 0.8 9.9 2.0 3.4 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain V-SNARE_C PF12352.8 ORY94845.1 - 3.6e-14 52.8 1.7 9.3e-14 51.5 1.7 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus CK2S PF15011.6 ORY94845.1 - 0.035 14.0 1.0 0.68 9.8 1.0 2.3 1 1 0 1 1 1 0 Casein Kinase 2 substrate Sec20 PF03908.13 ORY94845.1 - 0.058 13.3 1.2 0.36 10.8 0.0 2.6 3 1 0 3 3 3 0 Sec20 HpaB_N PF11794.8 ORY94845.1 - 0.093 12.4 0.0 0.4 10.3 0.0 1.9 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Stc1 PF12898.7 ORY94846.1 - 6.4e-20 71.5 24.3 3.4e-17 62.8 19.6 1.8 1 1 1 2 2 2 2 Stc1 domain DUF4820 PF16091.5 ORY94846.1 - 0.6 9.4 3.7 0.73 9.1 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RF-1 PF00472.20 ORY94847.1 - 2.3e-22 79.1 2.5 2.8e-22 78.8 2.5 1.1 1 0 0 1 1 1 1 RF-1 domain Ribosomal_60s PF00428.19 ORY94847.1 - 0.23 12.1 8.4 0.11 13.1 4.1 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein L51_S25_CI-B8 PF05047.16 ORY94848.1 - 4.5e-11 42.5 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain tRNA-synt_1g PF09334.11 ORY94849.1 - 2.9e-149 497.1 0.0 3.8e-149 496.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY94849.1 - 8.4e-08 30.9 0.1 8.4e-05 21.0 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) GST_C_3 PF14497.6 ORY94849.1 - 0.0029 17.8 0.7 0.0067 16.6 0.7 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Anticodon_1 PF08264.13 ORY94849.1 - 0.011 15.7 0.4 0.031 14.2 0.0 1.9 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA MetRS-N PF09635.10 ORY94849.1 - 0.011 16.2 1.0 0.036 14.6 0.4 2.1 2 0 0 2 2 2 0 MetRS-N binding domain zinc-ribbons_6 PF07191.12 ORY94849.1 - 0.031 14.2 2.9 0.074 13.0 2.9 1.6 1 0 0 1 1 1 0 zinc-ribbons GST_C PF00043.25 ORY94849.1 - 0.052 13.8 1.1 0.16 12.2 0.9 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DZR PF12773.7 ORY94849.1 - 1.1 9.4 7.3 4 7.6 7.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 ORY94850.1 - 2.7e-23 81.1 25.5 7.6e-07 29.2 0.5 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY94850.1 - 6.8e-23 80.0 22.9 5.5e-08 32.9 0.2 5.4 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY94850.1 - 4.9e-13 48.7 25.1 0.00061 20.4 1.1 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY94850.1 - 1.5e-05 25.1 5.8 0.39 11.1 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY94850.1 - 8.7e-05 22.8 8.1 3.6 8.1 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORY94850.1 - 0.0003 21.3 7.9 1.7 9.3 0.2 3.6 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-LYAR PF08790.11 ORY94850.1 - 0.0027 17.6 12.7 0.38 10.7 1.8 4.6 4 1 0 4 4 4 2 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 ORY94850.1 - 0.0031 17.2 19.0 0.38 10.5 1.0 3.6 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-TRAF PF02176.18 ORY94850.1 - 0.023 15.4 1.7 0.023 15.4 1.7 3.0 2 1 1 3 3 3 0 TRAF-type zinc finger BolA PF01722.18 ORY94850.1 - 0.13 12.6 1.4 27 5.1 0.2 3.2 3 1 0 3 3 3 0 BolA-like protein DUF3300 PF11737.8 ORY94851.1 - 0.09 12.3 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DUF508 PF04370.12 ORY94851.1 - 3.3 7.4 5.9 5.2 6.8 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) UPF0121 PF03661.13 ORY94852.1 - 7.7e-47 159.7 5.9 8.7e-47 159.5 5.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF4386 PF14329.6 ORY94852.1 - 0.057 13.3 8.8 0.038 13.9 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4386) KleE PF17394.2 ORY94852.1 - 0.22 11.8 3.4 1.2 9.4 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Ribosomal_L39 PF00832.20 ORY94854.1 - 3.1e-19 68.3 13.8 3.7e-19 68.1 13.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein MCM PF00493.23 ORY94855.1 - 2.1e-103 344.2 0.1 3.2e-103 343.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY94855.1 - 6.1e-38 129.5 0.1 1.1e-37 128.7 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 ORY94855.1 - 1.9e-23 83.5 20.1 1.9e-23 83.5 20.1 4.1 6 0 0 6 6 6 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 ORY94855.1 - 3.4e-21 75.4 0.2 7.9e-21 74.3 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY94855.1 - 3.3e-14 53.3 0.3 1.9e-13 50.9 0.1 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY94855.1 - 6.6e-10 38.7 0.1 9.7e-07 28.4 0.0 3.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY94855.1 - 2.2e-05 24.5 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY94855.1 - 0.00012 22.0 0.1 0.00053 19.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY94855.1 - 0.011 15.4 0.1 0.1 12.3 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_lid_2 PF17863.1 ORY94855.1 - 0.03 14.2 0.4 0.03 14.2 0.4 3.1 3 0 0 3 3 3 0 AAA lid domain AAA PF00004.29 ORY94855.1 - 0.11 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Yippee-Mis18 PF03226.14 ORY94855.1 - 0.16 12.2 0.2 0.32 11.2 0.2 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-HIT PF04438.16 ORY94855.1 - 8.1 6.4 5.5 1.7 8.6 0.1 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_jaz PF12171.8 ORY94857.1 - 2.9e-05 24.2 0.4 5.3e-05 23.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY94857.1 - 3.6e-05 24.0 0.1 6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.8 ORY94857.1 - 0.031 14.1 0.2 0.031 14.1 0.2 4.5 1 1 3 4 4 4 0 Domain of unknown function (DUF3449) zf-C2H2_2 PF12756.7 ORY94857.1 - 1.4 9.3 6.2 0.1 13.0 1.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DTW PF03942.15 ORY94859.1 - 4.8e-31 108.0 0.0 8.3e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.24 ORY94859.1 - 1.9 8.7 5.9 3.9 7.7 5.9 1.5 1 0 0 1 1 1 0 B-box zinc finger CybS PF05328.12 ORY94860.1 - 2.5e-38 130.8 0.0 2.9e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit MRI PF15325.6 ORY94861.1 - 1.1 10.4 3.6 1.8 9.7 3.6 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection HIG_1_N PF04588.13 ORY94863.1 - 2.2e-07 31.0 0.1 2.2e-07 31.0 0.1 2.9 3 1 0 3 3 3 1 Hypoxia induced protein conserved region Romo1 PF10247.9 ORY94863.1 - 0.034 14.5 3.2 0.034 14.5 3.2 1.7 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ENOD93 PF03386.14 ORY94863.1 - 0.05 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Alg14 PF08660.11 ORY94863.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like DUF3754 PF12576.8 ORY94863.1 - 0.1 12.5 0.4 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) DUF2723 PF11028.8 ORY94863.1 - 0.12 12.3 3.4 0.6 10.0 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2723) CD99L2 PF12301.8 ORY94863.1 - 0.17 12.2 0.4 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF4079 PF13301.6 ORY94863.1 - 0.17 12.0 2.0 0.63 10.2 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Gly-zipper_YMGG PF13441.6 ORY94863.1 - 0.54 10.0 7.9 0.055 13.2 3.4 1.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF1269 PF06897.12 ORY94863.1 - 1.3 9.4 3.8 10 6.4 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) ANAPC4_WD40 PF12894.7 ORY94864.1 - 0.044 14.1 0.0 12 6.2 0.0 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4477 PF14780.6 ORY94865.1 - 0.027 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) 2-oxoacid_dh PF00198.23 ORY94866.1 - 2.3e-81 272.7 0.4 3.2e-81 272.2 0.4 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY94866.1 - 1.1e-16 60.4 0.9 1.9e-16 59.6 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 ORY94866.1 - 0.00058 20.5 0.2 1.7 9.4 0.1 2.5 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 ORY94866.1 - 0.00059 19.7 0.2 0.0013 18.6 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein FAM76 PF16046.5 ORY94866.1 - 0.019 14.3 4.6 1.2 8.5 2.3 2.1 2 0 0 2 2 2 0 FAM76 protein Biotin_lipoyl_2 PF13533.6 ORY94866.1 - 0.092 12.6 0.0 2.5 8.0 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like Methyltransf_25 PF13649.6 ORY94867.1 - 1.2e-11 45.1 0.1 2e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY94867.1 - 2.9e-10 40.7 0.1 4.6e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY94867.1 - 9.8e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 ORY94867.1 - 1.1e-08 35.0 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY94867.1 - 4e-07 30.0 0.0 5.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY94867.1 - 1.1e-05 26.0 0.1 2.2e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY94867.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 ORY94867.1 - 0.0079 15.1 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 ORY94867.1 - 0.011 16.7 0.2 0.022 15.8 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ORY94867.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ORY94867.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Whi5 PF08528.11 ORY94868.1 - 0.0019 17.8 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 Whi5 like CRISPR_Cse2 PF09485.10 ORY94868.1 - 0.89 10.1 4.3 0.8 10.2 3.1 1.5 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Kei1 PF08552.11 ORY94869.1 - 0.0011 18.8 7.9 0.1 12.5 7.9 3.1 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ABC2_membrane_2 PF12679.7 ORY94869.1 - 0.49 9.6 4.7 1.2 8.4 4.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Copper-fist PF00649.18 ORY94870.1 - 2.5e-17 62.0 2.3 2.5e-17 62.0 2.3 3.4 2 1 1 3 3 3 2 Copper fist DNA binding domain Ribonuclease_T2 PF00445.18 ORY94871.1 - 3.1e-38 131.8 0.1 4.2e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family GrpE PF01025.19 ORY94872.1 - 0.12 12.1 5.3 0.33 10.6 2.0 2.2 2 0 0 2 2 2 0 GrpE AAA_11 PF13086.6 ORY94872.1 - 0.42 10.4 3.2 0.69 9.6 3.2 1.3 1 0 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.24 ORY94872.1 - 1.4 8.8 4.4 2.9 7.8 4.3 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD p450 PF00067.22 ORY94873.1 - 4.5e-76 256.5 0.0 5.8e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Autoind_bind PF03472.15 ORY94873.1 - 0.1 12.1 0.4 0.2 11.2 0.1 1.6 2 0 0 2 2 2 0 Autoinducer binding domain Hydrolase_like PF13242.6 ORY94874.1 - 7e-12 45.2 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ORY94874.1 - 8.5e-08 32.2 0.0 6.1e-07 29.5 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY94874.1 - 0.00021 21.7 0.0 0.078 13.3 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY94874.1 - 0.00048 20.2 0.0 0.0026 17.8 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase ERCC4 PF02732.15 ORY94875.1 - 9.1e-24 84.4 0.0 2e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain SAM_3 PF18016.1 ORY94875.1 - 0.1 12.4 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Plug PF07715.15 ORY94875.1 - 0.97 10.0 2.6 28 5.3 0.0 3.5 4 0 0 4 4 4 0 TonB-dependent Receptor Plug Domain DUF3402 PF11882.8 ORY94876.1 - 1.2e-98 331.2 13.3 9.4e-56 189.8 4.2 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 ORY94876.1 - 9.6e-47 159.5 0.0 2e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein Ribosomal_L30 PF00327.20 ORY94877.1 - 2.2e-06 27.4 0.2 5e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 ORY94877.1 - 0.024 14.9 9.5 0.024 14.9 9.5 2.4 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Pkinase PF00069.25 ORY94878.1 - 7.8e-55 186.1 0.0 6.6e-39 133.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94878.1 - 4.5e-22 78.6 0.0 1.1e-21 77.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY94878.1 - 1.7e-08 34.1 0.0 4.1e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY94878.1 - 6.6e-06 25.6 0.5 1e-05 25.0 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY94878.1 - 8.8e-05 22.5 0.1 0.00013 21.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY94878.1 - 0.005 15.8 0.2 0.0094 14.9 0.2 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY94878.1 - 0.0098 14.7 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 ORY94878.1 - 0.053 13.1 0.7 0.076 12.6 0.7 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CHCH PF06747.13 ORY94879.1 - 1.2e-08 34.8 3.3 2.3e-08 33.9 3.3 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 ORY94879.1 - 0.0026 18.2 2.3 0.0042 17.5 2.3 1.5 1 0 0 1 1 1 1 GCK domain PDZ_5 PF17817.1 ORY94880.1 - 0.026 14.8 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 PDZ domain Bap31_Bap29_C PF18035.1 ORY94880.1 - 0.098 12.7 0.6 1.5 8.9 0.1 2.1 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain TPR_1 PF00515.28 ORY94881.1 - 2.7e-15 55.5 7.7 6.5e-05 22.6 1.1 8.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY94881.1 - 6.6e-14 52.2 9.6 0.0013 19.2 0.0 7.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY94881.1 - 9.1e-13 47.3 18.6 0.00039 20.3 1.6 9.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY94881.1 - 7.7e-11 42.5 16.3 0.0013 19.4 0.4 5.8 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY94881.1 - 4.4e-10 39.2 4.3 0.64 10.5 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY94881.1 - 1.4e-09 37.4 9.5 0.015 15.5 0.6 8.2 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY94881.1 - 7.1e-07 28.8 5.1 0.094 12.4 0.0 5.9 7 0 0 7 7 7 2 TPR repeat TPR_12 PF13424.6 ORY94881.1 - 2.5e-06 27.7 24.6 0.0072 16.6 0.1 6.9 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_20 PF14561.6 ORY94881.1 - 3.6e-05 24.0 3.2 0.19 12.1 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY94881.1 - 6.2e-05 22.7 9.1 0.8 9.9 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY94881.1 - 0.00086 19.4 18.8 0.022 14.9 1.9 6.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY94881.1 - 0.0027 18.2 1.7 17 6.4 0.1 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY94881.1 - 0.0089 16.8 24.7 0.39 11.6 0.1 9.2 7 2 4 11 11 11 2 Tetratricopeptide repeat TPR_21 PF09976.9 ORY94881.1 - 0.052 13.2 1.1 3.6 7.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 ORY94881.1 - 0.21 11.8 15.2 0.21 11.9 0.7 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY94881.1 - 6.1 7.7 19.9 20 6.1 0.1 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Arf PF00025.21 ORY94882.1 - 2.4e-80 268.1 0.1 2.8e-80 267.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY94882.1 - 2.4e-14 53.6 0.0 3.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY94882.1 - 2.2e-13 50.1 1.2 1.8e-09 37.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY94882.1 - 2.7e-13 49.8 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY94882.1 - 5.3e-13 48.9 0.0 5.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY94882.1 - 2e-10 40.4 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY94882.1 - 6.6e-06 26.2 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY94882.1 - 0.0055 16.0 0.3 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Pkinase PF00069.25 ORY94883.1 - 1.7e-75 253.8 0.0 1.3e-32 113.2 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94883.1 - 9.5e-38 129.9 0.0 1.4e-12 47.5 0.0 4.4 4 0 0 4 4 4 4 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 ORY94883.1 - 1.8e-28 99.8 7.1 1.8e-28 99.8 7.1 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 ORY94883.1 - 3.3e-18 66.0 0.0 6.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 ORY94883.1 - 1.3e-17 64.1 0.2 6e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 RWD domain APH PF01636.23 ORY94883.1 - 1.9e-05 24.7 0.5 7.9e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 ORY94883.1 - 0.0073 16.4 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain Kinase-like PF14531.6 ORY94883.1 - 0.026 13.8 0.0 0.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Kinase-like FoP_duplication PF13865.6 ORY94884.1 - 5e-17 62.2 6.8 5e-17 62.2 6.8 2.7 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Nnf1 PF03980.14 ORY94884.1 - 0.094 13.1 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Nnf1 Dermcidin PF15291.6 ORY94884.1 - 0.24 12.0 6.6 0.25 11.9 4.0 2.3 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide HECT_2 PF09814.9 ORY94885.1 - 8.3e-36 123.6 0.3 9.9e-36 123.4 0.3 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.7 ORY94885.1 - 0.011 15.8 1.4 0.67 10.0 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Stc1 PF12898.7 ORY94885.1 - 0.025 15.1 0.6 0.086 13.4 0.2 1.9 2 0 0 2 2 2 0 Stc1 domain Yippee-Mis18 PF03226.14 ORY94885.1 - 0.027 14.7 1.2 0.66 10.2 1.2 2.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORY94885.1 - 0.076 13.3 0.0 8.8 6.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I VATC PF18716.1 ORY94885.1 - 1.7 8.6 4.2 24 4.9 0.2 3.2 3 0 0 3 3 3 0 Vms1-associating treble clef domain F-box-like PF12937.7 ORY94886.1 - 0.00017 21.4 0.3 0.00041 20.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY94886.1 - 0.004 17.1 2.8 0.044 13.9 0.0 3.7 4 0 0 4 4 4 1 Leucine Rich repeat STAS_2 PF13466.6 ORY94886.1 - 0.17 12.2 2.9 5 7.5 0.1 3.1 3 1 0 3 3 3 0 STAS domain E1_dh PF00676.20 ORY94887.1 - 1.3e-113 378.9 0.0 1.5e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component SET PF00856.28 ORY94889.1 - 5.1e-09 36.7 2.0 4.1e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 SET domain TLP-20 PF06088.11 ORY94889.1 - 0.35 10.8 4.0 0.46 10.4 4.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RRN3 PF05327.11 ORY94889.1 - 2.3 6.7 5.7 2.6 6.5 5.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC27 PF09507.10 ORY94890.1 - 3.9e-39 135.2 25.0 1.7e-26 93.6 4.5 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Peroxidase_2 PF01328.17 ORY94891.1 - 3.5e-42 145.0 0.0 5.2e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PDZ_1 PF12812.7 ORY94892.1 - 2.9e-40 136.1 0.0 3.9e-27 94.1 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ORY94892.1 - 5.2e-23 82.6 0.7 1.2e-17 65.3 0.0 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 ORY94892.1 - 5.5e-14 52.2 0.0 9.1e-06 25.9 0.0 3.9 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 ORY94892.1 - 6e-14 51.6 0.0 3.2e-05 23.7 0.0 4.0 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORY94892.1 - 3.7e-08 33.6 0.0 0.00061 20.1 0.0 3.5 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 ORY94892.1 - 0.0041 17.0 0.1 1.4 8.9 0.0 3.4 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 ORY94892.1 - 0.058 12.0 0.2 0.12 10.9 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.16 ORY94892.1 - 0.1 12.1 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) DUF2201_N PF13203.6 ORY94893.1 - 0.02 14.5 4.4 1.5 8.3 5.7 2.4 1 1 1 2 2 2 0 Putative metallopeptidase domain FlaC_arch PF05377.11 ORY94893.1 - 0.045 14.1 2.3 0.045 14.1 2.3 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RAP1 PF07218.11 ORY94893.1 - 0.35 9.1 6.9 0.5 8.6 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PRESAN PF09687.10 ORY94893.1 - 1.1 9.8 7.7 0.15 12.6 2.1 2.1 2 0 0 2 2 2 0 Plasmodium RESA N-terminal BAR_3 PF16746.5 ORY94894.1 - 9.9e-29 100.7 3.1 1.7e-28 100.0 3.1 1.3 1 0 0 1 1 1 1 BAR domain of APPL family VASt PF16016.5 ORY94894.1 - 4.1e-27 95.5 0.1 8.7e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 ORY94894.1 - 4.3e-09 36.8 0.0 8.3e-08 32.7 0.0 2.8 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 ORY94894.1 - 7.3e-08 32.3 0.0 1.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 ORY94894.1 - 0.0079 15.9 4.8 0.034 13.8 4.8 1.9 1 1 0 1 1 1 1 BAR domain Tape_meas_lam_C PF09718.10 ORY94894.1 - 0.35 11.0 1.6 0.87 9.8 0.0 2.5 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Dynamin_M PF01031.20 ORY94895.1 - 4.6e-104 347.6 1.5 5e-104 347.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORY94895.1 - 2.2e-55 187.2 0.0 4.4e-55 186.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY94895.1 - 3.8e-30 103.9 5.7 3.8e-30 103.9 5.7 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY94895.1 - 0.00084 19.4 2.3 0.0017 18.4 0.4 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY94895.1 - 0.12 12.0 8.2 1.7 8.2 0.2 3.1 3 0 0 3 3 3 0 AAA ATPase domain HSP90 PF00183.18 ORY94897.1 - 3.3e-176 587.2 14.4 3.3e-176 587.2 14.4 1.6 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 ORY94897.1 - 3.9e-12 46.7 0.1 9.1e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY94897.1 - 5.1e-11 42.6 0.1 1.7e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PPP4R2 PF09184.11 ORY94899.1 - 1.9e-28 99.9 20.5 1.9e-28 99.9 20.5 2.2 2 0 0 2 2 2 1 PPP4R2 Integrase_H2C2 PF17921.1 ORY94900.1 - 1.7e-08 34.5 1.7 2.6e-08 33.8 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 ORY94900.1 - 0.039 14.2 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Gti1_Pac2 PF09729.9 ORY94901.1 - 2.6e-56 190.6 16.5 3.2e-55 187.0 0.3 3.5 2 2 0 2 2 2 1 Gti1/Pac2 family TFIIA PF03153.13 ORY94901.1 - 0.17 11.9 16.4 0.25 11.3 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UCH PF00443.29 ORY94902.1 - 5.5e-44 150.6 0.0 9.7e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 ORY94902.1 - 7.3e-25 86.5 0.2 6.7e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 ORY94902.1 - 1.3e-23 84.1 1.8 6.1e-22 78.6 0.1 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 ORY94902.1 - 1.5e-21 75.9 8.4 2.2e-21 75.4 1.0 3.2 3 0 0 3 3 3 1 Variant UBP zinc finger zf-UBP PF02148.19 ORY94902.1 - 4.5e-20 71.8 23.3 6e-17 61.7 3.4 4.1 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_12 PF11331.8 ORY94902.1 - 0.16 11.8 4.4 1.8 8.4 0.1 3.6 3 0 0 3 3 3 0 Probable zinc-ribbon domain Arrestin_C PF02752.22 ORY94903.1 - 7.5e-09 36.1 0.0 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORY94903.1 - 0.035 13.3 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Rgp1 Arrestin_N PF00339.29 ORY94903.1 - 0.11 12.5 0.7 4.6 7.3 0.0 2.7 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Cwf_Cwc_15 PF04889.12 ORY94904.1 - 6.2e-80 268.5 31.9 7e-80 268.3 31.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 ORY94904.1 - 0.0042 16.7 10.3 0.007 16.0 10.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 ORY94904.1 - 0.11 11.2 28.5 0.14 10.9 28.5 1.1 1 0 0 1 1 1 0 Caldesmon IMUP PF15761.5 ORY94904.1 - 0.15 12.7 8.9 0.35 11.6 8.9 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3246 PF11596.8 ORY94904.1 - 0.16 11.4 4.6 0.19 11.1 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RR_TM4-6 PF06459.12 ORY94904.1 - 1.9 8.3 16.2 2.6 7.8 16.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 ORY94904.1 - 4.1 6.2 8.5 4.7 6.0 8.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SAPS PF04499.15 ORY94904.1 - 9.6 4.9 16.4 12 4.5 16.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ribosomal_L5_C PF00673.21 ORY94905.1 - 1e-27 96.1 0.0 1.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY94905.1 - 1e-12 48.2 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 LCAT PF02450.15 ORY94906.1 - 5e-87 292.6 0.0 4.6e-86 289.4 0.0 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 ORY94906.1 - 0.13 11.8 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 2) Hydrolase_4 PF12146.8 ORY94906.1 - 0.2 10.9 0.0 0.87 8.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 UQ_con PF00179.26 ORY94907.1 - 5.7e-21 74.6 0.0 1.2e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glycophorin_A PF01102.18 ORY94907.1 - 0.067 13.4 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A GET2 PF08690.10 ORY94907.1 - 0.091 12.4 0.6 0.12 12.1 0.6 1.3 1 1 0 1 1 1 0 GET complex subunit GET2 Ndc80_HEC PF03801.13 ORY94908.1 - 2.2e-22 79.3 0.2 2.2e-22 79.3 0.2 2.0 3 0 0 3 3 3 1 HEC/Ndc80p family DUF5595 PF18077.1 ORY94908.1 - 2e-08 34.2 0.5 2e-08 34.2 0.5 5.7 4 2 2 6 6 6 2 Domain of unknown function (DUF5595) Spc7 PF08317.11 ORY94908.1 - 0.017 14.0 53.8 0.012 14.5 4.5 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein TetR_C_37 PF18665.1 ORY94908.1 - 1.3 9.7 6.8 5.5 7.6 0.1 3.4 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain IFT57 PF10498.9 ORY94908.1 - 8.6 5.2 41.6 1.8 7.4 24.9 2.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Ligase_CoA PF00549.19 ORY94912.1 - 0.012 15.5 0.0 2.2 8.1 0.0 2.0 1 1 1 2 2 2 0 CoA-ligase NnrS PF05940.12 ORY94912.1 - 0.025 14.0 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 NnrS protein Death PF00531.22 ORY94912.1 - 0.046 13.9 0.0 2 8.7 0.0 2.0 1 1 1 2 2 2 0 Death domain UPF0370 PF13980.6 ORY94912.1 - 0.54 10.3 4.8 2.5 8.2 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Renin_r PF07850.14 ORY94912.1 - 2.8 8.6 4.4 23 5.7 0.3 2.1 1 1 1 2 2 2 0 Renin receptor-like protein GPI-anchored PF10342.9 ORY94914.1 - 1.8e-07 31.8 0.4 1.8e-07 31.8 0.4 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4454 PF14628.6 ORY94914.1 - 0.013 15.4 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Sporozoite_P67 PF05642.11 ORY94914.1 - 0.37 8.8 9.4 0.48 8.4 9.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C25_C PF03785.14 ORY94914.1 - 0.47 10.3 4.9 0.12 12.2 1.3 2.0 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Macoilin PF09726.9 ORY94914.1 - 1.9 7.0 5.1 2.1 6.8 5.1 1.1 1 0 0 1 1 1 0 Macoilin family AMP-binding PF00501.28 ORY94915.1 - 1.3e-104 350.2 0.2 1.7e-104 349.8 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY94915.1 - 0.025 15.5 0.1 0.081 13.9 0.1 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain E3_binding PF02817.17 ORY94915.1 - 0.084 13.2 0.0 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 e3 binding domain UCH PF00443.29 ORY94916.1 - 3e-60 203.9 0.0 2.6e-59 200.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ORY94916.1 - 3.4e-15 56.4 0.2 1.6e-13 51.0 0.1 2.6 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 ORY94916.1 - 3e-11 43.5 2.8 0.0031 17.2 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Spore_coat_CotO PF14153.6 ORY94916.1 - 0.27 11.2 10.5 2.4 8.1 11.4 2.2 2 0 0 2 2 2 0 Spore coat protein CotO PI3K_1B_p101 PF10486.9 ORY94916.1 - 1.3 6.7 7.1 2.6 5.7 7.1 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ANAPC15 PF15243.6 ORY94916.1 - 1.4 9.3 21.0 0.21 12.0 14.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Myc_N PF01056.18 ORY94916.1 - 1.6 8.5 15.5 0.15 11.9 6.9 2.6 3 0 0 3 3 3 0 Myc amino-terminal region TFB6 PF17110.5 ORY94916.1 - 1.8 8.3 7.3 11 5.7 7.3 2.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH GREB1 PF15782.5 ORY94916.1 - 2.5 5.1 9.1 3.7 4.6 9.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM176 PF14851.6 ORY94916.1 - 6.4 6.4 10.3 6.3 6.4 5.8 2.6 2 0 0 2 2 2 0 FAM176 family AA_permease PF00324.21 ORY94917.1 - 6.3e-129 430.7 49.8 7.5e-129 430.4 49.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY94917.1 - 1.3e-45 156.0 52.2 1.7e-45 155.6 52.2 1.2 1 0 0 1 1 1 1 Amino acid permease RabGAP-TBC PF00566.18 ORY94918.1 - 8.4e-41 140.0 0.4 8.4e-41 140.0 0.4 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Chi-conotoxin PF16981.5 ORY94918.1 - 0.16 12.2 0.4 0.48 10.7 0.1 2.0 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily RRM_1 PF00076.22 ORY94919.1 - 3.7e-31 106.8 0.0 9.1e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY94919.1 - 8.3e-05 22.6 0.0 0.01 15.9 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 ORY94919.1 - 0.012 15.3 0.0 2.9 7.5 0.0 2.1 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 ORY94919.1 - 0.17 11.6 0.2 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 ORY94919.1 - 0.18 11.9 0.0 0.79 9.9 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif KfrA_N PF11740.8 ORY94920.1 - 0.0068 17.1 3.8 0.0068 17.1 3.8 3.4 3 0 0 3 3 3 1 Plasmid replication region DNA-binding N-term Telomere_reg-2 PF10193.9 ORY94920.1 - 0.12 12.9 7.9 0.25 11.8 7.1 1.9 2 0 0 2 2 2 0 Telomere length regulation protein DUF2574 PF10836.8 ORY94920.1 - 0.26 11.2 1.2 42 4.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2574) Fib_alpha PF08702.10 ORY94920.1 - 0.53 10.5 23.0 0.023 14.9 13.1 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ORF6C PF10552.9 ORY94920.1 - 0.75 9.9 6.9 0.61 10.2 4.0 2.3 1 1 1 2 2 2 0 ORF6C domain VHS PF00790.19 ORY94921.1 - 1.9e-29 102.4 0.0 2.9e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 ORY94921.1 - 1.1e-15 57.6 3.3 1.2e-14 54.4 0.3 2.3 2 0 0 2 2 2 2 GAT domain PH PF00169.29 ORY94922.1 - 8.9e-17 61.5 0.5 1.6e-16 60.7 0.5 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY94922.1 - 0.00023 21.5 0.3 0.011 16.1 0.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 ORY94922.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 ORY94922.1 - 0.009 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF1418 PF07214.12 ORY94923.1 - 0.02 14.7 1.1 0.04 13.8 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) IspA PF04279.15 ORY94923.1 - 6.6 6.9 10.3 0.31 11.2 2.4 2.1 2 0 0 2 2 2 0 Intracellular septation protein A Pkinase PF00069.25 ORY94924.1 - 5.5e-42 143.9 0.0 7e-23 81.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY94924.1 - 6.9e-21 74.7 0.0 4.5e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 ORY94924.1 - 1.5e-05 25.1 0.0 3.4e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY94924.1 - 0.023 14.3 0.0 0.047 13.3 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 ORY94924.1 - 0.058 12.7 0.0 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like MRP-S35 PF10246.9 ORY94925.1 - 0.079 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 GATA PF00320.27 ORY94926.1 - 1.2e-15 56.8 4.4 1.2e-15 56.8 4.4 2.1 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.7 ORY94926.1 - 0.013 15.5 5.5 0.064 13.3 5.8 1.9 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 ORY94926.1 - 0.03 13.9 2.0 0.03 13.9 2.0 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 ORY94926.1 - 0.044 13.9 0.3 0.044 13.9 0.3 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_9 PF14369.6 ORY94926.1 - 0.13 12.6 0.9 0.13 12.6 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon DUF732 PF05305.14 ORY94927.1 - 0.00065 20.0 0.8 0.00081 19.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF732) Cse1 PF08506.10 ORY94927.1 - 0.12 11.1 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Cse1 Helicase_C PF00271.31 ORY94928.1 - 3.5e-07 30.5 0.0 8.8e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY94928.1 - 1.5e-06 28.1 0.1 0.00023 21.0 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Mito_carr PF00153.27 ORY94929.1 - 2.4e-59 197.3 0.4 2.6e-21 75.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY94929.1 - 0.059 12.5 0.1 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DUF5320 PF17253.2 ORY94931.1 - 0.13 13.4 35.0 8.9 7.4 1.5 6.1 3 2 1 5 5 5 0 Family of unknown function (DUF5320) AMP-binding PF00501.28 ORY94932.1 - 3e-84 283.1 0.0 3.7e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY94932.1 - 3e-11 44.1 0.2 1.1e-10 42.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DEAD PF00270.29 ORY94933.1 - 1.4e-40 139.0 0.0 3.7e-40 137.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY94933.1 - 1e-24 87.0 0.0 1e-22 80.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY94933.1 - 4.7e-11 43.0 0.0 8.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY94933.1 - 0.0012 19.1 0.3 0.22 11.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain SWI2_SNF2 PF18766.1 ORY94933.1 - 0.0093 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Flavi_DEAD PF07652.14 ORY94933.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SET PF00856.28 ORY94934.1 - 0.0055 17.1 0.0 0.039 14.4 0.0 1.9 1 1 0 1 1 1 1 SET domain Staphopain_pro PF14731.6 ORY94936.1 - 0.064 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Staphopain proregion Pep1_7 PF17232.2 ORY94936.1 - 0.14 12.6 1.1 0.37 11.3 0.3 2.1 2 0 0 2 2 2 0 Elicitor peptide 1-7 Chromo_shadow PF01393.19 ORY94937.1 - 1.5e-14 53.8 1.1 5.4e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 ORY94937.1 - 1.3e-11 44.2 7.5 2e-11 43.6 5.0 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Npa1 PF11707.8 ORY94937.1 - 0.019 14.3 0.1 0.019 14.3 0.1 1.5 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal Transmemb_17 PF09799.9 ORY94938.1 - 0.0056 17.3 6.5 0.0056 17.3 6.5 2.9 2 2 1 3 3 3 1 Predicted membrane protein DUF1772 PF08592.11 ORY94938.1 - 0.41 11.0 8.4 0.69 10.2 1.9 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) HIG_1_N PF04588.13 ORY94938.1 - 3.6 7.9 6.5 9.4 6.6 0.1 3.1 2 0 0 2 2 2 0 Hypoxia induced protein conserved region La PF05383.17 ORY94939.1 - 2.2e-17 62.9 0.1 3.5e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 La domain vATP-synt_AC39 PF01992.16 ORY94940.1 - 3.3e-117 391.7 1.0 3.7e-117 391.6 1.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit PCI PF01399.27 ORY94941.1 - 1.7e-12 47.8 0.4 2.8e-11 43.8 0.1 2.5 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 ORY94941.1 - 2e-10 40.2 1.3 5.9e-10 38.7 1.3 1.9 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix HTH_40 PF14493.6 ORY94941.1 - 0.028 14.9 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ORY94941.1 - 0.12 12.0 0.1 0.34 10.6 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1476 PF07345.11 ORY94941.1 - 0.34 11.3 3.4 8.8 6.8 0.1 3.2 3 0 0 3 3 3 0 ATPase inhibitor subunit zeta Chorismate_bind PF00425.18 ORY94942.1 - 5.1e-96 321.2 0.0 9.2e-96 320.4 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ORY94942.1 - 2.8e-28 98.9 0.0 3.6e-27 95.3 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region DUF5518 PF17647.1 ORY94943.1 - 0.0054 16.9 2.3 0.0078 16.4 2.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5518) Apq12 PF12716.7 ORY94943.1 - 0.048 13.6 12.9 0.08 12.9 12.9 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis MNHE PF01899.16 ORY94943.1 - 0.33 10.7 5.6 0.48 10.2 5.6 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit UCH PF00443.29 ORY94944.1 - 1.8e-54 184.9 0.1 2.9e-54 184.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY94944.1 - 1.1e-21 77.8 1.6 1.6e-20 73.9 1.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY94944.1 - 2.4e-16 59.8 8.7 2.4e-16 59.8 8.7 3.0 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.10 ORY94944.1 - 0.01 15.9 2.6 1.6 8.9 0.2 3.7 3 0 0 3 3 3 0 Zinc ribbon domain HalOD2 PF18547.1 ORY94944.1 - 0.024 14.5 0.3 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 Halobacterial output domain 2 zf_UBZ PF18439.1 ORY94944.1 - 0.67 9.6 4.2 10 5.8 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 ORY94944.1 - 1.2 8.6 9.2 4.1 7.0 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 ORY94944.1 - 1.7 9.2 18.0 1.8 9.2 0.3 5.3 5 0 0 5 5 5 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.12 ORY94944.1 - 7.5 6.2 11.3 7.6 6.1 0.2 3.6 4 0 0 4 4 3 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 ORY94944.1 - 7.6 6.6 9.4 9.8 6.2 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Ribosomal_L32p PF01783.23 ORY94944.1 - 9.1 6.6 9.7 2.7 8.3 1.8 3.7 4 0 0 4 4 4 0 Ribosomal L32p protein family MMS1_N PF10433.9 ORY94945.1 - 2.3e-79 267.3 0.0 2.4e-78 264.0 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY94945.1 - 2.8e-47 161.6 0.0 1.7e-46 159.0 0.0 2.4 3 0 0 3 3 3 1 CPSF A subunit region SWIB PF02201.18 ORY94946.1 - 1.8e-28 98.2 0.0 2.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3484 PF11983.8 ORY94948.1 - 0.08 14.1 3.0 0.31 12.2 3.0 1.9 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch GRAM PF02893.20 ORY94949.1 - 0.00032 20.5 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 ORY94949.1 - 0.0041 17.3 0.0 0.0092 16.1 0.0 1.6 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 ORY94949.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain GST_N_3 PF13417.6 ORY94950.1 - 5.7e-16 58.7 0.1 1.7e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY94950.1 - 8.4e-16 58.1 0.1 6.1e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY94950.1 - 2.6e-11 43.7 0.1 6.9e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY94950.1 - 4.4e-07 30.0 0.0 8.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY94950.1 - 1.7e-05 24.9 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY94950.1 - 0.00055 19.9 0.0 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain START PF01852.19 ORY94951.1 - 1.5e-19 70.2 1.0 9.5e-10 38.2 0.0 2.5 2 0 0 2 2 2 2 START domain Glyco_hydro_5_C PF18564.1 ORY94951.1 - 1.7e-06 28.5 0.3 1e-05 26.0 0.1 2.4 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain TFIIA PF03153.13 ORY94951.1 - 1.2 9.0 26.2 0.013 15.5 13.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY94951.1 - 1.7 8.2 22.4 0.086 12.4 16.6 1.8 2 0 0 2 2 2 0 Spt20 family TFIID-18kDa PF02269.16 ORY94952.1 - 1.2e-12 47.7 2.3 1.8e-12 47.1 0.4 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit NAD2 PF18782.1 ORY94952.1 - 0.049 13.7 0.2 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 TAFII28 PF04719.14 ORY94952.1 - 0.11 12.6 1.0 0.39 10.8 0.7 2.1 2 1 0 2 2 2 0 hTAFII28-like protein conserved region Ribosomal_60s PF00428.19 ORY94952.1 - 0.3 11.7 0.1 0.3 11.7 0.1 2.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein COesterase PF00135.28 ORY94956.1 - 1e-45 156.6 0.0 1.3e-45 156.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY94956.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 ORY94957.1 - 9.2e-29 100.7 0.3 1.1e-28 100.5 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Sec7 PF01369.20 ORY94958.1 - 1e-45 155.7 0.0 1.7e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 ORY94958.1 - 1.3e-05 25.6 0.0 0.027 15.0 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_10 PF15411.6 ORY94958.1 - 0.0025 18.1 1.9 0.0045 17.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 ORY94958.1 - 0.0088 15.9 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 ORY94958.1 - 0.016 15.1 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 PH domain G-gamma PF00631.22 ORY94959.1 - 2.9e-16 59.2 0.0 3.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain Myb_CC_LHEQLE PF14379.6 ORY94959.1 - 0.028 14.1 1.4 0.041 13.6 1.4 1.3 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Iso_dh PF00180.20 ORY94960.1 - 3.4e-96 322.4 0.0 7.9e-96 321.2 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_1 PF00036.32 ORY94961.1 - 2.5e-28 95.5 7.1 4.2e-06 25.9 0.0 5.7 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 ORY94961.1 - 5.1e-27 94.1 2.4 4.9e-11 42.9 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY94961.1 - 4e-26 88.7 7.0 3.3e-06 26.6 0.0 5.1 4 1 1 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 ORY94961.1 - 4.9e-20 70.1 7.0 2.1e-05 23.8 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 ORY94961.1 - 2e-19 69.1 6.5 8.1e-10 38.4 0.1 4.7 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_9 PF14658.6 ORY94961.1 - 0.00048 20.4 0.3 1.7 9.0 0.0 3.4 3 1 0 3 3 3 1 EF-hand domain DUF5640 PF18692.1 ORY94961.1 - 0.014 15.4 0.2 0.041 13.9 0.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5640) EFhand_Ca_insen PF08726.10 ORY94961.1 - 0.02 15.0 0.0 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 ORY94961.1 - 0.047 14.0 0.7 3 8.2 0.1 2.9 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY94961.1 - 0.048 13.6 0.7 0.099 12.6 0.2 1.8 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 ORY94961.1 - 0.057 12.0 0.0 2.3 6.7 0.0 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 ORY94961.1 - 0.17 12.3 0.1 0.48 10.8 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain SPRY PF00622.28 ORY94962.1 - 5.6e-22 78.1 0.2 5.6e-22 78.1 0.2 2.0 2 0 0 2 2 2 1 SPRY domain DUF4824 PF16106.5 ORY94962.1 - 0.087 12.1 0.9 0.14 11.4 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) DHHW PF14286.6 ORY94962.1 - 0.2 10.9 2.3 0.28 10.5 2.3 1.1 1 0 0 1 1 1 0 DHHW protein SPC25 PF06703.11 ORY94963.1 - 8.7e-43 145.9 2.5 1e-42 145.7 2.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Gag_p10 PF02337.17 ORY94963.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein Pyr_redox_2 PF07992.14 ORY94964.1 - 2.8e-63 213.9 0.1 3.7e-63 213.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY94964.1 - 7.1e-31 106.7 0.1 3.7e-30 104.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY94964.1 - 1.2e-21 77.1 2.5 1e-18 67.6 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY94964.1 - 8.9e-16 58.0 3.0 5.2e-15 55.5 3.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY94964.1 - 1.7e-09 37.6 0.0 2.3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY94964.1 - 2.2e-07 29.9 6.2 0.0088 14.8 2.0 4.1 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY94964.1 - 1.3e-05 24.6 1.2 0.022 14.1 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORY94964.1 - 5.1e-05 22.5 1.5 0.0044 16.2 1.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ORY94964.1 - 0.00021 20.7 0.9 0.00058 19.3 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY94964.1 - 0.00024 21.0 0.0 0.00064 19.7 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 ORY94964.1 - 0.00026 20.2 0.4 0.0019 17.4 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY94964.1 - 0.00034 20.8 7.3 0.0012 19.0 3.7 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY94964.1 - 0.00048 19.8 8.4 0.3 10.6 3.2 3.5 3 1 0 4 4 4 2 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORY94964.1 - 0.00065 19.3 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 ORY94964.1 - 0.0012 18.2 1.4 0.0066 15.7 0.3 2.7 4 0 0 4 4 4 1 Thi4 family FAD_binding_2 PF00890.24 ORY94964.1 - 0.0035 16.5 8.1 0.013 14.6 3.1 3.4 5 0 0 5 5 5 1 FAD binding domain NAD_binding_7 PF13241.6 ORY94964.1 - 0.011 16.2 0.1 0.12 12.8 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 ORY94964.1 - 0.016 15.3 0.1 0.041 14.0 0.1 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 ORY94964.1 - 0.025 13.9 4.5 11 5.1 0.0 3.8 4 0 0 4 4 4 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 ORY94964.1 - 0.25 11.3 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 ORY94964.1 - 1.1 8.2 3.2 1.2 8.1 1.4 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3899 PF13038.6 ORY94965.1 - 0.34 11.5 0.2 0.34 11.5 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Sugar_tr PF00083.24 ORY94966.1 - 6.7e-131 437.3 15.6 7.7e-131 437.1 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY94966.1 - 5.1e-29 101.3 43.6 2.1e-27 96.0 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY94966.1 - 2.2e-05 23.1 1.0 2.2e-05 23.1 1.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DnaJ PF00226.31 ORY94967.1 - 4.9e-27 93.8 1.1 7.9e-27 93.2 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain TraG_N PF07916.11 ORY94967.1 - 0.14 11.0 0.6 0.19 10.5 0.6 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SUIM_assoc PF16619.5 ORY94967.1 - 4 7.6 12.3 0.86 9.7 4.7 2.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 ORY94967.1 - 5.2 6.2 9.4 0.089 12.0 2.6 1.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal zf-C2H2 PF00096.26 ORY94969.1 - 2.7e-09 37.0 13.0 3.5e-05 24.0 1.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY94969.1 - 3.6e-07 30.5 11.8 0.0026 18.5 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY94969.1 - 5e-06 26.7 20.4 0.00012 22.4 2.7 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY94969.1 - 0.0024 18.1 3.5 0.15 12.4 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY94969.1 - 0.021 15.0 0.2 0.026 14.7 0.2 1.3 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 ORY94969.1 - 0.028 14.4 6.5 0.049 13.7 1.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 ORY94969.1 - 0.26 11.7 4.4 8.5 6.9 0.4 2.9 2 2 1 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY94969.1 - 3.6 7.4 10.7 0.43 10.4 0.6 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain FtsJ PF01728.19 ORY94970.1 - 3.4e-58 196.7 0.1 4e-58 196.4 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 ORY94970.1 - 0.0015 18.3 0.0 0.46 10.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORY94970.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 ORY94971.1 - 1.2e-50 171.7 0.0 5.3e-50 169.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY94971.1 - 2.4e-34 118.0 0.2 2.3e-29 102.0 0.0 3.4 2 1 1 3 3 3 3 Helicase conserved C-terminal domain AP3D1 PF06375.11 ORY94971.1 - 0.25 11.6 20.5 0.56 10.4 20.5 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Zip PF02535.22 ORY94971.1 - 0.49 9.6 2.8 0.61 9.3 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CMS1 PF14617.6 ORY94971.1 - 0.85 8.9 0.0 0.85 8.9 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SR-25 PF10500.9 ORY94971.1 - 1.5 8.4 20.0 3 7.4 20.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Membralin PF09746.9 ORY94971.1 - 2 7.4 8.5 3.5 6.6 8.5 1.3 1 0 0 1 1 1 0 Tumour-associated protein Vfa1 PF08432.10 ORY94971.1 - 7.4 6.9 23.9 17 5.7 23.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 VPS13_mid_rpt PF16910.5 ORY94972.1 - 2.5e-86 289.0 19.8 4.5e-82 275.0 1.9 7.0 7 1 0 7 7 7 4 Repeating coiled region of VPS13 VPS13 PF16908.5 ORY94972.1 - 1.1e-83 280.7 1.9 3.5e-77 259.4 0.0 4.6 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 ORY94972.1 - 2.1e-69 232.8 2.6 1.7e-64 216.9 0.1 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 ORY94972.1 - 6.4e-66 222.5 0.0 7e-64 215.8 0.0 3.0 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 ORY94972.1 - 7.4e-39 132.5 0.4 7.4e-39 132.5 0.4 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORY94972.1 - 1.2e-07 32.0 0.0 3.5e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain MID_MedPIWI PF18296.1 ORY94972.1 - 0.86 9.3 16.5 1.7 8.3 8.2 3.6 3 1 0 3 3 3 0 MID domain of medPIWI ADH_zinc_N PF00107.26 ORY94973.1 - 3.4e-22 78.8 0.1 9.1e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY94973.1 - 3.2e-14 52.7 0.0 6.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY94973.1 - 1.2e-07 32.8 0.0 2.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PMM PF03332.13 ORY94974.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase RGS PF00615.19 ORY94976.1 - 2.9e-28 98.5 0.0 6.4e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 ORY94976.1 - 2.9e-13 49.7 0.7 3.9e-08 33.2 0.2 2.7 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LpoB PF13036.6 ORY94976.1 - 0.0066 16.4 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Peptidoglycan-synthase activator LpoB PGK PF00162.19 ORY94977.1 - 4.6e-147 489.9 0.1 5.2e-147 489.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 ORY94977.1 - 0.057 13.4 0.2 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 PA domain Ras PF00071.22 ORY94978.1 - 6e-54 182.0 0.0 6.9e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY94978.1 - 3e-22 79.1 0.0 4.2e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY94978.1 - 1.7e-07 30.8 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 ORY94978.1 - 0.11 12.2 0.0 4.5 7.0 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DHBP_synthase PF00926.19 ORY94979.1 - 0.027 14.0 0.2 0.042 13.4 0.2 1.2 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Sad1_UNC PF07738.13 ORY94981.1 - 3.8e-27 94.9 0.0 6.6e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal FH2 PF02181.23 ORY94982.1 - 2.9e-72 243.8 10.4 2.9e-72 243.8 10.4 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORY94982.1 - 4.8e-30 104.5 6.1 3.6e-29 101.7 0.0 3.9 4 1 0 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORY94982.1 - 3e-24 85.7 1.1 1e-23 84.0 0.1 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain SMC_hinge PF06470.13 ORY94982.1 - 0.14 12.5 0.1 0.53 10.6 0.1 2.0 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain MPM1 PF17234.2 ORY94982.1 - 1 9.6 9.3 0.11 12.8 3.9 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 SLD5_C PF16922.5 ORY94983.1 - 3.8e-12 46.2 0.0 7.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 ORY94983.1 - 1.4e-06 28.7 0.9 3.3e-06 27.5 0.7 1.6 1 1 0 1 1 1 1 GINS complex protein RPE65 PF03055.15 ORY94984.1 - 2.3e-69 234.8 0.0 2.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein NAD_binding_2 PF03446.15 ORY94985.1 - 1.6e-38 132.4 1.5 2.3e-38 131.9 1.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY94985.1 - 7.2e-33 113.4 0.4 1.9e-32 112.0 0.0 1.9 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PDH PF02153.17 ORY94985.1 - 0.012 14.7 0.3 0.015 14.3 0.3 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase HopA1 PF17914.1 ORY94985.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 HopA1 effector protein family DUF3730 PF12530.8 ORY94987.1 - 8.1e-06 25.6 7.3 8.1e-06 25.6 7.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) SNF2_N PF00176.23 ORY94988.1 - 4.6e-56 190.0 0.2 7.1e-56 189.4 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY94988.1 - 5e-20 71.9 0.0 8e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY94988.1 - 7e-09 35.9 0.0 2.6e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY94988.1 - 3.3e-06 26.5 0.1 8.3e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase F-box-like PF12937.7 ORY94989.1 - 1.8e-07 30.9 0.4 6.9e-07 29.1 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY94989.1 - 2.9e-07 30.2 0.4 1.2e-06 28.3 0.4 2.1 1 0 0 1 1 1 1 F-box domain ThrE PF06738.12 ORY94990.1 - 1.4e-37 129.4 26.8 6.7e-35 120.6 7.6 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY94990.1 - 1.4e-09 38.2 30.7 9.8e-08 32.2 13.3 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE BaffR-Tall_bind PF09256.10 ORY94990.1 - 0.088 12.6 1.0 4.3 7.2 0.1 2.4 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding DUF2148 PF09918.9 ORY94990.1 - 2.3 8.3 5.8 0.33 11.0 0.7 2.2 3 0 0 3 3 3 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) PPI_Ypi1 PF07491.11 ORY94991.1 - 2.4e-20 72.1 17.4 2.4e-20 72.1 17.4 3.4 2 1 1 3 3 3 1 Protein phosphatase inhibitor BUD22 PF09073.10 ORY94991.1 - 0.0023 17.4 13.2 0.0027 17.1 13.2 1.0 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 ORY94991.1 - 0.0043 15.7 5.8 0.0043 15.7 5.8 1.7 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CCDC106 PF15794.5 ORY94991.1 - 0.0074 16.0 8.5 0.0074 16.0 8.5 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 AF-4 PF05110.13 ORY94991.1 - 0.013 13.7 15.7 0.016 13.4 15.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein YqfQ PF14181.6 ORY94991.1 - 0.28 11.4 4.2 0.47 10.6 4.2 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.14 ORY94991.1 - 0.9 7.8 13.2 0.093 11.0 9.1 1.3 1 1 0 1 1 1 0 CDC45-like protein DUF5427 PF10310.9 ORY94991.1 - 0.99 8.3 8.3 1.1 8.1 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SR-25 PF10500.9 ORY94991.1 - 1.8 8.1 28.1 0.14 11.8 22.2 1.8 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sox_N PF12444.8 ORY94991.1 - 2 9.6 13.6 26 6.0 9.4 2.2 2 0 0 2 2 2 0 Sox developmental protein N terminal IMUP PF15761.5 ORY94991.1 - 2.8 8.7 18.9 0.053 14.2 11.4 2.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein YL1 PF05764.13 ORY94991.1 - 3.3 7.8 15.9 4.7 7.3 15.7 1.4 1 1 0 1 1 1 0 YL1 nuclear protein Steroid_dh PF02544.16 ORY94992.1 - 4.1e-12 46.3 0.2 5.5e-12 45.9 0.2 1.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase HMA PF00403.26 ORY94993.1 - 1.7e-83 275.0 3.8 2.8e-14 53.3 0.0 7.5 7 0 0 7 7 7 7 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 ORY94993.1 - 1.3e-49 168.2 0.8 1.3e-49 168.2 0.8 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORY94993.1 - 8.2e-35 121.0 0.3 2.6e-34 119.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY94993.1 - 0.00067 19.5 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.6 ORY94993.1 - 0.00084 19.4 6.4 0.59 10.3 0.1 5.5 6 0 0 6 6 6 1 Papain fold toxin 2 FeS_assembly_P PF01883.19 ORY94993.1 - 0.0025 17.9 0.7 15 5.8 0.0 5.7 5 1 1 6 6 6 1 Iron-sulfur cluster assembly protein HAD PF12710.7 ORY94993.1 - 0.0039 17.6 0.0 0.0097 16.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TusA PF01206.17 ORY94993.1 - 0.12 12.3 1.2 36 4.3 0.0 4.0 4 0 0 4 4 4 0 Sulfurtransferase TusA AMP-binding PF00501.28 ORY94994.1 - 2.4e-68 230.7 0.0 3.4e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY94994.1 - 1.4e-11 45.2 0.0 2.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RS4NT PF08071.12 ORY94994.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 RS4NT (NUC023) domain adh_short PF00106.25 ORY94995.1 - 9.8e-33 113.3 0.2 4.5e-31 107.8 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY94995.1 - 1.3e-21 77.2 0.1 4.6e-20 72.2 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY94995.1 - 1e-05 25.5 0.4 0.00013 21.9 0.2 2.1 1 1 1 2 2 2 1 KR domain Glyco_trans_4_2 PF13477.6 ORY94995.1 - 0.049 13.7 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like THF_DHG_CYH_C PF02882.19 ORY94995.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_4 PF13439.6 ORY94995.1 - 0.13 12.2 0.0 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 UBD PF16455.5 ORY94997.1 - 8.5e-20 70.9 0.2 1.9e-19 69.8 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin-binding domain DUF2407 PF10302.9 ORY94997.1 - 2.9e-06 27.8 0.1 5.6e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 ORY94997.1 - 0.0015 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 ORY94997.1 - 0.0098 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LEA_2 PF03168.13 ORY94997.1 - 0.13 12.8 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein ACPS PF01648.20 ORY94998.1 - 1.8e-14 53.8 0.0 3.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GvpO PF05800.11 ORY94998.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO 4HBT PF03061.22 ORY94999.1 - 1.6e-26 92.4 1.3 5.6e-12 45.9 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.25 ORY94999.1 - 0.14 12.2 0.0 13 5.9 0.0 2.6 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain SF3b1 PF08920.10 ORY95000.1 - 5.2e-40 136.6 5.3 5.2e-40 136.6 5.3 3.1 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 ORY95000.1 - 3e-11 42.6 3.9 1.7 9.1 0.0 9.0 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 ORY95000.1 - 3.6e-11 43.3 1.0 0.93 10.1 0.0 7.6 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 ORY95000.1 - 6.4e-10 39.3 3.3 0.2 12.1 0.0 6.8 3 2 5 8 8 7 3 HEAT repeats Adaptin_N PF01602.20 ORY95000.1 - 1.9e-06 26.7 1.5 0.013 14.1 0.2 3.2 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 ORY95000.1 - 1.3e-05 25.3 5.7 0.34 11.0 0.0 6.0 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY95000.1 - 6.6e-05 23.4 2.4 1.3 9.7 0.0 4.6 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 ORY95000.1 - 0.00019 20.7 0.8 0.56 9.3 0.0 3.9 3 1 1 4 4 4 2 Dopey, N-terminal MMS19_C PF12460.8 ORY95000.1 - 0.019 14.1 0.0 8.4 5.4 0.0 3.6 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Arm PF00514.23 ORY95000.1 - 0.033 14.2 0.6 58 3.9 0.0 4.9 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat NUC173 PF08161.12 ORY95000.1 - 0.05 13.3 0.4 9 5.9 0.0 4.3 3 2 1 4 4 4 0 NUC173 domain TAF6_C PF07571.13 ORY95000.1 - 0.062 13.6 0.0 0.32 11.4 0.0 2.3 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Tti2 PF10521.9 ORY95000.1 - 0.065 12.8 0.1 18 4.8 0.0 3.1 2 1 1 3 3 3 0 Tti2 family TIP120 PF08623.10 ORY95000.1 - 0.22 11.3 4.9 2.9 7.6 0.0 4.2 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) 40S_SA_C PF16122.5 ORY95000.1 - 1.9 9.9 9.2 3.3 9.1 7.5 2.3 1 1 1 2 2 2 0 40S ribosomal protein SA C-terminus Abhydro_lipase PF04083.16 ORY95001.1 - 4.5e-19 67.8 0.0 9.5e-19 66.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ORY95001.1 - 6.7e-09 35.8 0.4 1.3e-08 34.8 0.2 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY95001.1 - 5.1e-07 29.2 0.0 0.00025 20.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 HU-CCDC81_bac_2 PF18175.1 ORY95001.1 - 0.18 11.7 0.1 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 CNH PF00780.22 ORY95002.1 - 5e-53 180.5 0.0 8.9e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY95002.1 - 1.7e-34 119.7 0.5 4.4e-34 118.3 0.5 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY95002.1 - 4e-18 65.8 0.0 1.2e-16 61.0 0.0 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 ORY95002.1 - 0.001 18.9 0.1 3.3 7.6 0.0 3.3 3 0 0 3 3 3 2 PH domain PH PF00169.29 ORY95002.1 - 0.0015 19.0 0.0 0.0087 16.6 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 ORY95002.1 - 0.0024 17.7 0.8 0.16 11.7 0.0 3.7 3 2 0 3 3 3 1 Pleckstrin homology domain RhoGAP PF00620.27 ORY95003.1 - 3.7e-27 95.0 0.0 7.5e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 ORY95003.1 - 1.4e-26 93.0 0.0 3.1e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 ORY95003.1 - 1.1e-09 38.1 7.1 0.0005 20.1 0.0 2.5 2 0 0 2 2 2 2 WW domain FYRN PF05964.14 ORY95004.1 - 7.6e-22 76.9 1.0 1.2e-21 76.2 1.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY95004.1 - 1.8e-13 50.4 0.0 2.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus SNARE_assoc PF09335.11 ORY95006.1 - 1.7e-13 51.1 3.2 1.7e-13 51.1 3.2 2.2 2 1 0 2 2 2 1 SNARE associated Golgi protein MHYT PF03707.16 ORY95006.1 - 0.75 10.0 9.7 0.2 11.9 0.6 3.3 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Asp4 PF16996.5 ORY95006.1 - 0.94 9.3 2.3 12 5.7 0.4 2.5 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 Lipase_GDSL PF00657.22 ORY95007.1 - 7.1e-14 52.3 0.0 8.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY95007.1 - 7.2e-08 33.0 0.0 1.1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HR1 PF02185.16 ORY95007.1 - 0.039 14.1 1.0 0.57 10.3 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat RhoGEF PF00621.20 ORY95008.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 RhoGEF domain FeoB_associated PF12669.7 ORY95008.1 - 0.17 12.3 0.2 0.37 11.2 0.2 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF1035 PF06281.12 ORY95008.1 - 9.7 6.3 8.0 28 4.8 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) bZIP_1 PF00170.21 ORY95009.1 - 1.7e-05 24.8 12.9 1.7e-05 24.8 12.9 3.5 3 1 0 3 3 3 1 bZIP transcription factor VIR_N PF15912.5 ORY95009.1 - 0.19 11.3 25.5 0.039 13.6 15.8 2.3 2 0 0 2 2 2 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 ORY95009.1 - 3.2 7.8 17.0 3.8 7.5 8.9 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 ORY95009.1 - 4.5 7.0 12.9 20 4.9 10.0 2.1 2 0 0 2 2 2 0 Connexin LMBR1 PF04791.16 ORY95009.1 - 4.8 6.0 8.8 6.3 5.6 8.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Otopetrin PF03189.13 ORY95009.1 - 5 5.8 6.0 8.6 5.1 6.0 1.4 1 0 0 1 1 1 0 Otopetrin MFS_1 PF07690.16 ORY95010.1 - 2e-15 56.6 40.6 2e-15 56.6 40.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORY95010.1 - 2.9e-11 43.3 8.1 1.1e-10 41.4 8.1 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 BPL_N PF09825.9 ORY95010.1 - 0.043 12.9 0.6 0.066 12.3 0.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal MFS_1 PF07690.16 ORY95011.1 - 8.8e-15 54.5 38.5 8.8e-15 54.5 38.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY95011.1 - 5.2e-10 39.3 6.3 5.2e-10 39.3 6.3 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 LIDHydrolase PF10230.9 ORY95012.1 - 6.4e-58 196.4 0.1 9.1e-58 195.9 0.1 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ORY95012.1 - 3.1e-06 26.6 0.0 3.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY95012.1 - 1.1e-05 26.1 0.1 1.3e-05 25.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY95012.1 - 0.00063 19.5 0.1 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ORY95012.1 - 0.009 15.7 1.6 0.055 13.2 0.7 2.5 2 1 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 ORY95012.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2920 PF11144.8 ORY95012.1 - 0.048 12.8 0.1 1.4 8.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2920) HEAT_EZ PF13513.6 ORY95013.1 - 7.5e-29 99.8 10.9 5.3e-13 49.2 0.0 9.1 7 2 2 9 9 9 5 HEAT-like repeat HEAT PF02985.22 ORY95013.1 - 3.6e-24 82.8 8.1 0.00015 21.7 0.0 9.3 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 ORY95013.1 - 1.7e-15 57.1 0.4 0.00029 21.2 0.0 6.9 5 3 2 7 7 7 3 HEAT repeats IBN_N PF03810.19 ORY95013.1 - 3.4e-12 46.1 0.0 1.4e-11 44.1 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cnd1 PF12717.7 ORY95013.1 - 2.6e-08 34.1 0.2 2.3 8.2 0.0 4.8 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY95013.1 - 3.2e-07 30.9 0.0 1.5 9.5 0.0 5.8 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 ORY95013.1 - 1.7e-06 27.8 7.9 3.5 7.8 0.0 7.4 8 0 0 8 8 7 3 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 ORY95013.1 - 5.8e-05 22.9 0.0 0.039 13.7 0.0 4.0 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) DUF3437 PF11919.8 ORY95013.1 - 0.00062 19.6 0.2 0.8 9.7 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) MMS19_C PF12460.8 ORY95013.1 - 0.0017 17.6 4.6 0.51 9.4 0.0 4.2 2 2 1 4 4 4 1 RNAPII transcription regulator C-terminal TAF6_C PF07571.13 ORY95013.1 - 0.0018 18.5 0.0 1.5 9.2 0.0 4.4 4 0 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain Cohesin_HEAT PF12765.7 ORY95013.1 - 0.0021 18.3 0.2 3.5 8.0 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 ORY95013.1 - 0.0064 15.1 0.4 18 3.8 0.0 3.6 3 1 0 3 3 3 0 Adaptin N terminal region UME PF08064.13 ORY95013.1 - 0.048 13.6 0.2 1.2 9.1 0.0 3.1 2 0 0 2 2 2 0 UME (NUC010) domain RasGEF_N_2 PF14663.6 ORY95013.1 - 0.072 13.5 1.0 1.8 9.0 0.0 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RNA_pol_3_Rpc31 PF11705.8 ORY95013.1 - 0.23 11.7 12.6 0.37 11.0 12.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 ORY95013.1 - 0.29 11.1 2.7 0.66 10.0 2.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 ORY95013.1 - 4.7 6.9 10.8 7.1 6.3 10.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MRG PF05712.13 ORY95014.1 - 1.4e-49 168.1 3.2 2.2e-49 167.5 3.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 ORY95014.1 - 7.5e-11 41.8 0.7 1.5e-10 40.8 0.7 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 ORY95014.1 - 0.095 13.1 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 PWWP domain Chromo PF00385.24 ORY95014.1 - 0.12 12.3 5.6 0.18 11.7 3.9 2.3 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Phytochelatin PF05023.14 ORY95018.1 - 1.1e-65 220.9 0.1 1.5e-65 220.4 0.1 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Ribosomal_L22 PF00237.19 ORY95019.1 - 1.8e-40 137.3 0.4 1.8e-40 137.3 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Rdx PF10262.9 ORY95020.1 - 2.8e-32 110.7 0.0 4e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Rdx family HRXXH PF13933.6 ORY95021.1 - 0.00015 21.4 6.5 0.86 9.1 0.1 4.3 2 1 1 4 4 4 3 Putative peptidase family Peptidase_C71 PF12386.8 ORY95021.1 - 0.028 14.1 0.7 40 3.9 0.0 3.6 4 0 0 4 4 4 0 Pseudomurein endo-isopeptidase Pei RAB3GAP2_N PF14655.6 ORY95021.1 - 0.03 13.6 7.8 0.12 11.6 1.4 2.2 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CCP_MauG PF03150.14 ORY95021.1 - 0.15 12.7 22.9 2 9.0 0.4 4.6 1 1 3 4 4 4 0 Di-haem cytochrome c peroxidase Antimicrobial_2 PF08023.12 ORY95021.1 - 0.89 10.1 3.3 1.7e+02 2.8 0.0 3.9 4 0 0 4 4 4 0 Frog antimicrobial peptide RE_HpaII PF09561.10 ORY95021.1 - 1.2 8.5 7.5 5 6.4 0.2 3.6 1 1 3 4 4 4 0 HpaII restriction endonuclease tRNA-synt_1d PF00750.19 ORY95022.1 - 1.1e-89 300.9 0.1 1.4e-89 300.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY95022.1 - 2.3e-25 89.1 0.2 8.1e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain Peptidase_M13_N PF05649.13 ORY95024.1 - 1.8e-100 337.3 0.0 2.4e-100 336.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY95024.1 - 2.3e-71 239.6 0.0 3.5e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 ORY95024.1 - 0.14 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 Mito_carr PF00153.27 ORY95025.1 - 7.9e-62 205.2 6.5 9.2e-22 76.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY95025.1 - 0.074 12.2 0.0 0.43 9.7 0.0 2.1 2 0 0 2 2 2 0 Gammaproteobacterial serine protease RCC1 PF00415.18 ORY95026.1 - 2.6e-19 69.6 1.1 0.00023 21.7 0.0 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 ORY95026.1 - 4e-19 68.9 0.3 3.2e-08 33.8 0.0 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 ORY95026.1 - 3.9e-11 43.2 0.3 0.00056 20.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY95026.1 - 6.2e-11 42.7 0.0 1.7e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY95026.1 - 2.7e-08 33.9 0.2 0.0023 18.3 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.6 ORY95026.1 - 3.6e-08 33.0 0.2 1.7e-06 27.7 0.0 3.2 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 ORY95026.1 - 2.3e-07 30.6 1.0 0.019 15.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY95026.1 - 2e-05 24.8 0.7 0.041 14.2 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2182 PF09948.9 ORY95026.1 - 0.092 12.6 0.4 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) Ndc1_Nup PF09531.10 ORY95026.1 - 0.4 9.3 8.9 0.9 8.1 8.9 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Acetyltransf_1 PF00583.25 ORY95027.1 - 7.1e-09 35.9 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY95027.1 - 6.5e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY95027.1 - 1.5e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY95027.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein CDT1_C PF16679.5 ORY95027.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Mito_carr PF00153.27 ORY95028.1 - 8.3e-63 208.4 1.1 5.2e-22 77.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SAT PF16073.5 ORY95028.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Got1 PF04178.12 ORY95029.1 - 6.7e-31 107.0 19.6 1e-30 106.4 18.9 1.6 1 1 1 2 2 2 2 Got1/Sft2-like family PhoLip_ATPase_C PF16212.5 ORY95029.1 - 0.47 10.2 18.6 2 8.1 18.5 1.8 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal 2-Hacid_dh_C PF02826.19 ORY95030.1 - 2e-57 193.4 0.0 2.9e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY95030.1 - 8.8e-32 109.6 0.0 1.1e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY95030.1 - 1.8e-05 24.9 0.0 3.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY95030.1 - 0.0018 18.8 0.0 0.0039 17.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ORY95030.1 - 0.0047 16.5 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 ORY95030.1 - 0.005 16.9 0.0 0.03 14.4 0.0 2.2 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORY95030.1 - 0.0084 16.5 0.0 0.055 13.9 0.0 2.1 2 1 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ORY95030.1 - 0.025 14.8 0.2 2 8.7 0.2 3.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORY95030.1 - 0.05 13.9 0.3 0.8 10.0 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain DEAD PF00270.29 ORY95031.1 - 9.3e-41 139.5 0.8 4.9e-40 137.2 0.1 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY95031.1 - 6.5e-32 110.2 0.3 6.2e-31 107.0 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY95031.1 - 8.9e-06 25.8 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY95031.1 - 0.001 19.4 0.5 0.0099 16.2 0.5 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY95031.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 ORY95031.1 - 0.09 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 ORY95031.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF4637 PF15470.6 ORY95032.1 - 0.22 11.3 0.1 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Ecl1 PF12855.7 ORY95040.1 - 1.8e-09 39.0 1.8 2e-09 38.9 1.8 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PHF5 PF03660.14 ORY95040.1 - 0.037 14.2 1.0 0.043 14.0 0.7 1.3 1 1 0 1 1 1 0 PHF5-like protein zf-C6H2 PF15801.5 ORY95040.1 - 0.044 14.1 0.5 0.044 14.1 0.5 1.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORY95040.1 - 0.059 13.5 1.4 0.12 12.4 1.4 1.5 1 0 0 1 1 1 0 MYND finger DUF2116 PF09889.9 ORY95040.1 - 0.079 13.0 0.5 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Catalase PF00199.19 ORY95041.1 - 1.3e-166 554.5 0.1 1.7e-166 554.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 ORY95041.1 - 1.1e-35 122.5 0.0 1.8e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ORY95041.1 - 6.7e-14 51.9 0.3 1.7e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive AFOR_C PF01314.18 ORY95041.1 - 0.05 12.6 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Thioredoxin PF00085.20 ORY95042.1 - 1.2e-25 89.5 0.1 1.4e-25 89.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY95042.1 - 3e-06 27.6 0.1 9.3e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY95042.1 - 8.2e-06 26.1 0.1 0.0028 18.0 0.1 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 ORY95042.1 - 8.8e-05 22.3 0.0 9.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORY95042.1 - 0.00011 21.7 0.1 0.00012 21.5 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 ORY95042.1 - 0.00032 20.6 0.0 0.00059 19.8 0.0 1.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 ORY95042.1 - 0.00098 19.0 0.2 0.0015 18.5 0.2 1.5 1 1 0 1 1 1 1 AhpC/TSA family Methyltransf_2 PF00891.18 ORY95042.1 - 0.051 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Redoxin PF08534.10 ORY95042.1 - 0.068 12.9 0.2 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 Redoxin Phosducin PF02114.16 ORY95042.1 - 0.1 11.5 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_7 PF13899.6 ORY95042.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like SpoIIE PF07228.12 ORY95043.1 - 6.8e-13 49.0 0.0 2e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 ORY95043.1 - 2.6e-10 40.4 0.2 2e-05 24.4 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 ORY95043.1 - 9.9e-09 35.1 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Amidohydro_1 PF01979.20 ORY95044.1 - 6.1e-63 213.2 0.0 7.3e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY95044.1 - 4.1e-09 36.4 0.3 7.1e-07 29.1 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family AA_kinase PF00696.28 ORY95045.1 - 1.6e-38 132.7 0.2 2.4e-38 132.1 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORY95045.1 - 3.8e-19 68.4 0.0 3.8e-19 68.4 0.0 2.3 3 0 0 3 3 3 1 PUA domain zf-LITAF-like PF10601.9 ORY95046.1 - 1.3e-19 70.2 1.5 2.1e-19 69.5 1.5 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.6 ORY95046.1 - 0.026 14.2 2.4 0.4 10.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 ORY95046.1 - 0.073 12.5 1.9 2.1 7.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 ORY95046.1 - 0.082 13.0 0.9 0.96 9.5 0.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 ORY95046.1 - 0.1 12.5 0.4 0.1 12.5 0.4 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 ORY95046.1 - 0.16 12.0 0.2 6.1 6.9 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbons Nudix_N_2 PF14803.6 ORY95046.1 - 0.49 10.4 3.3 2.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-C2H2_jaz PF12171.8 ORY95046.1 - 0.77 10.1 3.0 10 6.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding UDPG_MGDP_dh_N PF03721.14 ORY95047.1 - 5.7e-65 218.4 0.2 1.4e-64 217.2 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 ORY95047.1 - 1.9e-36 124.7 0.4 9.2e-35 119.2 0.1 2.9 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 ORY95047.1 - 2.2e-30 104.7 0.0 4.4e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 ORY95047.1 - 0.00093 19.7 0.1 1.2 9.7 0.0 3.2 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORY95047.1 - 0.0024 18.0 0.0 0.3 11.2 0.0 2.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ORY95047.1 - 0.0029 17.3 0.0 0.0073 16.0 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 ORY95047.1 - 0.031 14.5 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thioredoxin PF00085.20 ORY95048.1 - 7.1e-21 74.1 0.0 8.8e-21 73.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 ORY95048.1 - 0.031 14.0 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF3885 PF13021.6 ORY95048.1 - 0.034 14.3 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Thioredoxin_8 PF13905.6 ORY95048.1 - 0.044 14.1 0.0 0.16 12.3 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like DUF3087 PF11286.8 ORY95048.1 - 0.15 11.6 0.1 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Thioredoxin PF00085.20 ORY95050.1 - 1.9e-24 85.6 0.0 2.3e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY95050.1 - 4e-05 24.0 0.1 0.00021 21.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ORY95050.1 - 9.2e-05 22.2 0.0 9.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY95050.1 - 0.00013 22.3 0.0 0.011 16.1 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY95050.1 - 0.0022 17.9 0.1 0.0056 16.6 0.0 1.5 1 1 1 2 2 2 1 AhpC/TSA family OST3_OST6 PF04756.13 ORY95050.1 - 0.0069 15.8 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 ORY95050.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredox_DsbH PF03190.15 ORY95050.1 - 0.027 14.4 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 TraF PF13728.6 ORY95050.1 - 0.061 13.1 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 ORY95050.1 - 0.064 13.4 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 ORY95050.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.3 1 1 0 1 1 1 0 Redoxin Thioredoxin_4 PF13462.6 ORY95050.1 - 0.15 12.2 0.2 15 5.7 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin UDPG_MGDP_dh_C PF03720.15 ORY95051.1 - 6.1e-13 49.1 0.0 6.6e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Thioredoxin PF00085.20 ORY95052.1 - 5.6e-27 93.7 0.0 6.6e-27 93.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 ORY95052.1 - 4.9e-08 32.8 0.0 5.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY95052.1 - 1.3e-06 28.8 0.2 8.6e-06 26.2 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY95052.1 - 0.00019 20.9 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORY95052.1 - 0.00023 21.4 0.0 0.0076 16.6 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.6 ORY95052.1 - 0.002 18.0 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 ORY95052.1 - 0.0026 17.7 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY95052.1 - 0.018 14.7 0.2 0.43 10.3 0.1 2.2 1 1 1 2 2 2 0 Redoxin HyaE PF07449.11 ORY95052.1 - 0.061 13.3 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 ORY95052.1 - 0.078 13.2 0.1 0.1 12.8 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like LBP_BPI_CETP_C PF02886.17 ORY95052.1 - 0.18 11.2 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain WD40 PF00400.32 ORY95053.1 - 5.5e-25 87.2 3.7 7e-09 36.2 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY95053.1 - 1.8e-06 28.1 0.9 0.026 14.8 0.0 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ORY95053.1 - 1.1e-05 25.2 0.5 2e-05 24.4 0.5 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 ORY95053.1 - 1.1e-05 24.4 1.4 3.9e-05 22.5 0.2 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY95053.1 - 0.00093 18.2 0.5 0.0085 15.1 0.2 2.7 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY95053.1 - 0.0015 18.5 0.1 0.12 12.2 0.0 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORY95053.1 - 0.22 11.5 2.0 29 4.8 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cation_efflux PF01545.21 ORY95054.1 - 1.2e-30 106.8 12.2 1.6e-30 106.4 12.2 1.2 1 0 0 1 1 1 1 Cation efflux family DUF1180 PF06679.12 ORY95055.1 - 3.5 8.0 13.5 1.2e+02 3.0 13.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) CRM1_C PF08767.11 ORY95056.1 - 9.5e-07 28.3 2.2 8.5e-06 25.1 0.0 3.1 3 1 0 3 3 3 1 CRM1 C terminal Importin_rep_6 PF18829.1 ORY95056.1 - 0.13 12.4 0.2 0.75 10.0 0.1 2.3 2 0 0 2 2 2 0 Importin repeat 6 PLATZ PF04640.14 ORY95057.1 - 0.069 13.8 2.4 0.069 13.8 2.4 2.6 3 1 0 3 3 3 0 PLATZ transcription factor zf-C6H2 PF15801.5 ORY95057.1 - 0.13 12.6 1.7 0.33 11.3 0.8 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Aa_trans PF01490.18 ORY95058.1 - 1.7e-90 303.7 21.3 2.1e-90 303.4 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY95058.1 - 1e-08 34.7 13.4 1e-08 34.7 13.4 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Adeno_E3_14_5 PF04834.12 ORY95058.1 - 0.73 10.4 4.5 0.34 11.5 0.2 2.7 3 0 0 3 3 3 0 Early E3 14.5 kDa protein Myb_DNA-bind_6 PF13921.6 ORY95059.1 - 0.0001 22.5 1.0 0.00027 21.1 1.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY95059.1 - 0.0009 19.4 1.8 0.0018 18.4 1.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 ORY95059.1 - 0.23 11.8 0.1 0.23 11.8 0.1 3.0 2 1 1 3 3 3 0 Centromere protein B dimerisation domain Cation_ATPase_C PF00689.21 ORY95060.1 - 6.7e-47 159.5 8.8 6.7e-47 159.5 8.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY95060.1 - 3.8e-35 121.0 1.9 3.8e-35 121.0 1.9 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY95060.1 - 1.6e-18 67.8 0.0 4.2e-18 66.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY95060.1 - 1.5e-15 57.0 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY95060.1 - 5.7e-10 38.7 0.5 7.2e-09 35.2 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY95060.1 - 3.1e-06 27.1 0.2 2.5e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GP57 PF17594.2 ORY95060.1 - 0.14 11.9 0.6 12 5.7 0.0 3.5 2 1 1 3 3 3 0 Phage Tail fiber assembly helper gene product 57 Phage_holin_4_1 PF05105.12 ORY95060.1 - 4.9 7.3 10.8 0.34 11.1 0.7 3.5 3 1 0 3 3 3 0 Bacteriophage holin family RIBIOP_C PF04950.12 ORY95061.1 - 2.7e-90 302.8 0.6 2.7e-90 302.8 0.6 2.1 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY95061.1 - 2.2e-31 107.8 0.1 2e-30 104.7 0.0 2.8 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 ORY95061.1 - 3.4e-06 26.8 0.0 0.00048 19.7 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY95061.1 - 2e-05 24.9 0.0 6.5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY95061.1 - 0.00016 22.1 0.0 0.00037 20.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY95061.1 - 0.00025 21.5 0.0 0.0011 19.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY95061.1 - 0.0005 20.3 0.0 0.0022 18.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORY95061.1 - 0.00057 19.9 0.1 0.0073 16.4 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY95061.1 - 0.0051 17.4 0.0 0.0051 17.4 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORY95061.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORY95061.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 ORY95061.1 - 0.018 15.4 0.0 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 ORY95061.1 - 0.026 13.8 4.3 0.11 11.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 ORY95061.1 - 0.027 15.0 0.0 0.027 15.0 0.0 3.0 3 0 0 3 3 3 0 ABC transporter NTPase_1 PF03266.15 ORY95061.1 - 0.033 14.1 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 ORY95061.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ORY95061.1 - 0.037 14.4 0.1 0.087 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY95061.1 - 0.049 13.4 0.0 0.049 13.4 0.0 4.5 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 ORY95061.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ORY95061.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.9 3 0 0 3 3 1 0 AAA domain NACHT PF05729.12 ORY95061.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ACT_7 PF13840.6 ORY95062.1 - 8.9e-22 76.7 0.0 1.9e-21 75.6 0.0 1.5 2 0 0 2 2 2 1 ACT domain MatE PF01554.18 ORY95063.1 - 3.1e-57 192.7 38.7 9.2e-33 113.2 10.1 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 ORY95063.1 - 1.5e-09 38.1 38.2 7.6e-08 32.5 14.5 3.9 2 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 ORY95063.1 - 0.035 14.2 0.1 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ParA PF10609.9 ORY95064.1 - 1.8e-100 335.5 0.7 2e-100 335.3 0.7 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY95064.1 - 1.7e-13 50.8 0.0 4.2e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY95064.1 - 6e-10 39.3 1.1 1.3e-07 31.7 0.2 2.2 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.18 ORY95064.1 - 1.2e-08 34.7 0.1 3.2e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 ORY95064.1 - 1.8e-05 24.2 0.3 4.1e-05 23.0 0.3 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 ORY95064.1 - 0.0015 17.7 2.0 0.013 14.7 0.7 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 ORY95064.1 - 0.0032 17.1 2.2 0.0078 15.8 2.2 1.7 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 ORY95064.1 - 0.025 13.9 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein PhnA_Zn_Ribbon PF08274.12 ORY95064.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Lgl_C PF08596.10 ORY95064.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal CobA_CobO_BtuR PF02572.15 ORY95064.1 - 0.27 11.5 1.4 0.48 10.7 1.4 1.6 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP zf-C2H2_2 PF12756.7 ORY95068.1 - 0.071 13.5 3.3 0.13 12.6 3.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) fn3_5 PF06280.12 ORY95068.1 - 0.096 13.4 0.2 4.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Fn3-like domain DUF3294 PF07957.11 ORY95069.1 - 0.075 12.8 0.3 0.2 11.4 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) Polyketide_cyc PF03364.20 ORY95072.1 - 5.2e-22 78.4 0.2 6.4e-22 78.2 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ORY95072.1 - 0.0013 19.0 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Arm PF00514.23 ORY95073.1 - 1.7e-28 97.7 0.1 5.5e-07 29.4 0.0 6.3 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY95073.1 - 1.3e-07 31.9 0.4 0.03 14.9 0.0 5.3 3 1 2 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 ORY95073.1 - 5.5e-06 26.7 0.2 0.67 10.4 0.0 4.5 2 2 2 4 4 4 2 HEAT repeats Cnd1 PF12717.7 ORY95073.1 - 0.0011 19.1 0.0 0.64 10.0 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY95073.1 - 0.0024 18.0 0.8 7.2 7.2 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat IBB PF01749.20 ORY95073.1 - 0.06 13.8 2.5 0.16 12.4 2.5 1.8 1 0 0 1 1 1 0 Importin beta binding domain DUF4672 PF15716.5 ORY95073.1 - 0.28 10.8 2.4 0.45 10.1 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) RNA_pol_Rpc82 PF05645.13 ORY95074.1 - 1.9e-14 54.1 0.0 1e-13 51.7 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 ORY95074.1 - 0.0037 17.1 0.4 0.032 14.1 0.0 2.7 2 2 0 2 2 2 1 TFIIE alpha subunit Tubulin PF00091.25 ORY95075.1 - 8.4e-68 228.5 0.0 1.3e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY95075.1 - 2.9e-46 156.7 0.2 8.9e-46 155.2 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY95075.1 - 5.2e-05 23.5 0.0 0.00015 22.0 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY95075.1 - 0.003 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain UPF0669 PF17065.5 ORY95075.1 - 0.036 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 HEAT_2 PF13646.6 ORY95078.1 - 4.5e-40 135.9 2.5 9.1e-14 51.6 0.1 3.7 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 ORY95078.1 - 1.7e-23 80.8 0.0 0.0015 19.0 0.0 6.5 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT PF02985.22 ORY95078.1 - 6.3e-10 38.5 0.0 0.1 12.9 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 ORY95078.1 - 0.0021 18.5 0.8 0.56 10.8 0.0 4.4 5 2 1 6 6 6 1 HEAT-like repeat TAF6_C PF07571.13 ORY95078.1 - 0.0028 17.9 0.1 8.3 6.8 0.1 3.3 3 1 0 3 3 3 2 TAF6 C-terminal HEAT repeat domain DUF1447 PF07288.11 ORY95078.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) Arm PF00514.23 ORY95078.1 - 0.061 13.4 0.0 16 5.7 0.0 3.2 2 1 1 3 3 3 0 Armadillo/beta-catenin-like repeat Arrestin_N PF00339.29 ORY95079.1 - 2.1e-06 27.9 0.0 0.3 11.1 0.0 3.4 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY95079.1 - 2.4e-06 28.1 0.0 0.00011 22.7 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain OB_NTP_bind PF07717.16 ORY95080.1 - 4.3e-23 81.5 0.0 5.9e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HTH_27 PF13463.6 ORY95080.1 - 0.089 13.3 0.0 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain DEAD PF00270.29 ORY95081.1 - 4.9e-09 36.2 0.1 7.9e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY95081.1 - 1.1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY95081.1 - 2.5e-05 24.6 0.0 4.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY95081.1 - 5.9e-05 22.9 0.0 8.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY95081.1 - 0.0056 16.7 0.2 0.26 11.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY95081.1 - 0.011 15.3 0.1 0.035 13.6 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 ORY95081.1 - 0.015 15.3 0.4 0.34 10.9 0.4 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORY95081.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 ORY95081.1 - 0.02 15.4 0.2 0.12 12.8 0.2 2.1 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 ORY95081.1 - 0.051 13.2 0.1 0.086 12.5 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NAP PF00956.18 ORY95081.1 - 0.061 12.5 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Zeta_toxin PF06414.12 ORY95081.1 - 0.073 12.3 0.3 0.25 10.6 0.1 1.9 1 1 1 2 2 2 0 Zeta toxin AAA_33 PF13671.6 ORY95081.1 - 0.077 13.1 0.1 0.35 11.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY95081.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY95081.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 ORY95081.1 - 0.23 11.9 0.8 16 5.9 0.1 3.1 3 1 0 3 3 3 0 AAA domain zf-CCCH_4 PF18044.1 ORY95082.1 - 7.7e-09 35.2 13.9 0.00012 21.8 2.5 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Thioredoxin PF00085.20 ORY95082.1 - 3.6e-07 30.1 0.1 7.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin zf_CCCH_4 PF18345.1 ORY95082.1 - 6.6e-07 29.2 18.5 6.8e-06 26.0 4.5 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORY95082.1 - 0.00011 22.0 9.5 0.0045 16.9 1.8 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY95082.1 - 0.00016 22.3 5.7 0.0013 19.4 0.9 5.1 4 1 1 5 5 5 2 Torus domain Thioredoxin_2 PF13098.6 ORY95082.1 - 0.022 15.2 0.4 0.091 13.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain zf-CCCH_2 PF14608.6 ORY95082.1 - 0.052 14.0 15.0 0.16 12.5 2.8 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Thioredoxin_3 PF13192.6 ORY95082.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin PF00085.20 ORY95083.1 - 2.8e-27 94.7 0.2 3.2e-27 94.5 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY95083.1 - 2.1e-05 24.9 0.1 6.2e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ORY95083.1 - 0.00054 19.7 0.0 0.00064 19.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 ORY95083.1 - 0.0019 18.3 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 ORY95083.1 - 0.0029 17.0 0.1 0.0029 17.0 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ORY95083.1 - 0.0036 17.2 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ORY95083.1 - 0.0048 17.2 0.0 0.0072 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 ORY95083.1 - 0.02 15.1 0.2 0.043 14.1 0.2 1.6 1 1 0 1 1 1 0 Glutaredoxin Redoxin PF08534.10 ORY95083.1 - 0.13 12.0 0.1 0.16 11.7 0.1 1.3 1 1 0 1 1 1 0 Redoxin Phosducin PF02114.16 ORY95083.1 - 0.19 10.7 0.0 0.21 10.5 0.0 1.0 1 0 0 1 1 1 0 Phosducin RSN1_7TM PF02714.15 ORY95085.1 - 4.1e-67 226.4 33.4 7.3e-67 225.6 33.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY95085.1 - 5.4e-36 123.7 2.2 5.4e-36 123.7 2.2 3.4 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY95085.1 - 1.4e-32 113.3 0.1 2.3e-32 112.6 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter EBP PF05241.12 ORY95087.1 - 9.7e-59 197.8 11.2 1.1e-58 197.6 11.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF5305 PF17231.2 ORY95087.1 - 0.043 13.2 0.5 0.84 9.0 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4271 PF14093.6 ORY95087.1 - 1.1 9.1 5.1 0.16 11.9 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) IncD PF17628.2 ORY95087.1 - 2.3 8.0 6.0 0.39 10.5 1.8 1.8 2 0 0 2 2 2 0 Inclusion membrane protein D TMEM132D_C PF15706.5 ORY95087.1 - 9.6 6.1 6.1 1.4 8.8 0.7 2.0 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Fungal_trans PF04082.18 ORY95088.1 - 1.2e-35 122.9 0.0 1.2e-35 122.9 0.0 2.2 3 0 0 3 3 2 1 Fungal specific transcription factor domain EOS1 PF12326.8 ORY95088.1 - 0.099 12.6 0.8 2.5 8.0 0.2 2.3 2 0 0 2 2 2 0 N-glycosylation protein MecA PF05389.12 ORY95088.1 - 1.5 8.4 10.3 0.75 9.4 2.5 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF719 PF05334.13 ORY95088.1 - 2.3 8.4 16.0 7.1 6.8 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) eIF-3_zeta PF05091.12 ORY95088.1 - 3.5 6.5 20.8 1.1 8.1 9.7 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2870 PF11069.8 ORY95088.1 - 3.7 8.0 12.4 0.4 11.1 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Connexin PF00029.19 ORY95088.1 - 5.3 6.7 7.9 1.4 8.6 0.5 2.4 2 0 0 2 2 2 0 Connexin Peptidase_S49_N PF08496.10 ORY95088.1 - 5.5 7.0 11.5 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4175 PF13779.6 ORY95088.1 - 6.1 4.6 42.1 1.4 6.7 24.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) EPL1 PF10513.9 ORY95088.1 - 8.7 6.7 22.1 1.7 9.0 8.1 2.7 3 0 0 3 3 3 0 Enhancer of polycomb-like PAT1 PF09770.9 ORY95088.1 - 9.5 4.3 43.9 1.5 7.0 23.8 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CDT1_C PF16679.5 ORY95088.1 - 10 6.7 14.9 3.1 8.3 0.2 2.8 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain PX PF00787.24 ORY95089.1 - 1.4e-17 63.7 0.0 2.5e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF3653 PF12375.8 ORY95089.1 - 0.03 14.4 0.2 0.51 10.5 0.0 2.7 2 0 0 2 2 2 0 Phage protein SNARE PF05739.19 ORY95089.1 - 0.033 14.2 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 SNARE domain Exo_endo_phos PF03372.23 ORY95211.1 - 0.01 15.3 0.1 0.045 13.2 0.1 1.9 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 ORY95211.1 - 0.36 11.0 18.0 0.11 12.6 2.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 ORY95211.1 - 6.1 6.8 18.2 3.3 7.6 8.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Lactamase_B_4 PF13691.6 ORY95212.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNase Z endonuclease Lactamase_B_2 PF12706.7 ORY95213.1 - 6.5e-16 58.4 1.9 1.6e-15 57.2 1.9 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY95213.1 - 3.7e-06 27.1 0.1 1e-05 25.7 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SNase PF00565.17 ORY95214.1 - 1.7e-63 211.8 0.2 4.7e-18 65.6 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 ORY95214.1 - 2.9e-29 101.6 0.0 5.9e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 ORY95214.1 - 0.00033 20.0 0.0 0.00087 18.6 0.0 1.7 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3297 PF11730.8 ORY95214.1 - 0.019 14.8 0.2 0.34 10.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3297) ApbA PF02558.16 ORY95215.1 - 7e-33 113.4 0.0 1.5e-32 112.4 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ORY95215.1 - 7.6e-30 103.7 0.2 1.1e-29 103.2 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Mito_carr PF00153.27 ORY95216.1 - 3.6e-61 203.1 3.8 6.5e-21 74.1 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY95216.1 - 0.026 13.7 0.1 0.42 9.7 0.0 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease PaO PF08417.12 ORY95216.1 - 0.035 14.3 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase eIF2_C PF09173.11 ORY95217.1 - 5.5e-34 116.3 1.7 1.3e-33 115.1 0.4 2.2 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ORY95217.1 - 1.8e-23 83.1 1.5 1.4e-22 80.2 1.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY95217.1 - 2.5e-09 37.4 1.7 8.9e-09 35.6 1.7 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ORY95217.1 - 0.00019 21.4 0.5 0.0026 17.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY95217.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ORY95217.1 - 0.013 15.5 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 ORY95217.1 - 0.051 13.6 0.0 0.23 11.5 0.0 2.0 2 1 0 3 3 3 0 Dynamin family G-alpha PF00503.20 ORY95217.1 - 0.14 11.3 0.1 2.3 7.3 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit tRNA-synt_2b PF00587.25 ORY95218.1 - 7.7e-38 130.2 0.1 2.6e-37 128.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORY95218.1 - 1.8e-24 86.1 4.9 1.8e-24 86.1 4.9 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cadherin_pro PF08758.11 ORY95218.1 - 0.013 15.7 0.2 0.03 14.5 0.2 1.6 1 0 0 1 1 1 0 Cadherin prodomain like TetR_C_23 PF17931.1 ORY95218.1 - 0.023 14.8 2.7 0.053 13.6 2.7 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 ORY95219.1 - 6.9e-52 176.5 33.0 6.9e-52 176.5 33.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY95219.1 - 4.1e-12 45.7 11.9 4.1e-12 45.7 11.9 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ORY95219.1 - 5.4e-06 25.1 3.4 9.2e-06 24.3 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 ORY95219.1 - 0.00068 18.3 11.8 0.00068 18.3 11.8 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein PTR2 PF00854.21 ORY95219.1 - 0.0012 17.8 0.6 0.0012 17.8 0.6 2.5 3 0 0 3 3 3 1 POT family UL42 PF17638.2 ORY95219.1 - 0.32 11.0 1.1 0.94 9.5 0.2 2.1 2 0 0 2 2 2 0 HCMV UL42 Caveolin PF01146.17 ORY95219.1 - 1.6 8.7 10.4 0.22 11.5 1.4 3.2 3 1 0 3 3 3 0 Caveolin WI12 PF07107.11 ORY95220.1 - 0.035 14.2 0.1 0.071 13.2 0.0 1.5 2 0 0 2 2 2 0 Wound-induced protein WI12 MFS_1 PF07690.16 ORY95221.1 - 9.7e-50 169.5 26.6 1.2e-49 169.1 26.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY95221.1 - 2.1e-15 56.6 4.7 2.1e-15 56.6 4.7 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORY95221.1 - 8e-06 24.5 2.6 1.4e-05 23.7 2.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 ORY95221.1 - 0.0017 17.0 8.7 0.0017 17.0 8.7 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Glucosamine_iso PF01182.20 ORY95222.1 - 4.1e-20 72.6 0.0 6e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ATP_sub_h PF10775.9 ORY95222.1 - 0.023 14.7 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 ATP synthase complex subunit h Pox_ser-thr_kin PF05445.11 ORY95222.1 - 0.15 11.0 0.2 0.35 9.8 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Exo_endo_phos PF03372.23 ORY95223.1 - 1.4e-21 77.1 0.0 7.7e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Bac_surface_Ag PF01103.23 ORY95224.1 - 1.6e-42 146.2 0.0 2.1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Ribosomal_L19 PF01245.20 ORY95224.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L19 LAP1C PF05609.12 ORY95225.1 - 3.1 6.8 16.1 3.7 6.5 16.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GIT1_C PF12205.8 ORY95225.1 - 7.7 6.7 15.2 0.074 13.2 3.4 2.9 2 1 1 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Pmp3 PF01679.17 ORY95228.1 - 3.8e-18 65.4 7.1 4.8e-18 65.1 7.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PTPLA PF04387.14 ORY95228.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA YojJ PF10372.9 ORY95229.1 - 0.074 13.2 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Fungal_trans PF04082.18 ORY95230.1 - 1e-30 106.7 0.0 2.4e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAP_N PF01213.19 ORY95230.1 - 1.2 8.5 5.2 2.4 7.5 5.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Reticulon PF02453.17 ORY95231.1 - 1.5e-23 83.5 1.8 1.8e-23 83.2 1.8 1.1 1 0 0 1 1 1 1 Reticulon DUF1838 PF08894.11 ORY95232.1 - 3.1e-77 259.5 0.2 3.6e-77 259.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) SKN1 PF03935.15 ORY95233.1 - 1.6e-179 597.5 0.1 1.9e-179 597.2 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SPT_ssu-like PF11779.8 ORY95234.1 - 1.5e-17 63.0 3.0 1.6e-17 62.9 3.0 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF2313 PF10076.9 ORY95234.1 - 0.074 12.9 0.1 0.086 12.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) Sds3 PF08598.11 ORY95236.1 - 7.9e-07 29.3 5.0 1.3e-06 28.5 5.0 1.4 1 1 0 1 1 1 1 Sds3-like MAP17 PF15807.5 ORY95237.1 - 0.0083 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LMBR1 PF04791.16 ORY95237.1 - 0.094 11.6 0.8 0.14 11.0 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EphA2_TM PF14575.6 ORY95237.1 - 0.12 13.2 0.0 0.54 11.2 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 ORY95237.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TRP PF06011.12 ORY95237.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EB PF01683.18 ORY95237.1 - 0.69 10.2 34.8 0.81 10.0 7.0 4.4 2 1 2 4 4 4 0 EB module Dickkopf_N PF04706.12 ORY95237.1 - 2.4 8.7 31.8 0.11 12.9 5.4 3.6 3 1 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region PLA2_B PF01735.18 ORY95239.1 - 8.3e-42 143.2 0.0 1.3e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Haem_bd PF14376.6 ORY95239.1 - 0.13 12.2 0.0 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain Mito_carr PF00153.27 ORY95240.1 - 8.3e-27 92.9 7.8 2e-11 43.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FUN14 PF04930.15 ORY95241.1 - 9.1e-21 74.1 2.5 1.1e-20 73.8 2.5 1.1 1 0 0 1 1 1 1 FUN14 family CcmF_C PF16327.5 ORY95243.1 - 0.001 18.4 0.1 0.001 18.4 0.1 1.7 2 1 0 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal SH3_9 PF14604.6 ORY95244.1 - 1.3e-14 53.7 0.1 1.4e-14 53.6 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY95244.1 - 5.1e-10 38.8 0.0 5.7e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY95244.1 - 4.4e-06 26.3 0.0 4.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain MerT PF02411.15 ORY95245.1 - 1.2e-09 38.3 3.7 8.4e-09 35.5 2.2 2.6 2 1 0 2 2 2 1 MerT mercuric transport protein HMA PF00403.26 ORY95245.1 - 2.5e-08 34.2 0.2 5.2e-08 33.2 0.1 1.5 2 0 0 2 2 2 1 Heavy-metal-associated domain Spore_YhcN_YlaJ PF09580.10 ORY95245.1 - 0.2 11.7 0.0 0.26 11.3 0.0 1.3 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PHP PF02811.19 ORY95246.1 - 3.4e-07 30.7 0.0 4.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 PHP domain PHP_C PF13263.6 ORY95246.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 PHP-associated CoatB PF10389.9 ORY95246.1 - 0.5 10.3 4.2 1.2 9.0 4.2 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B MFS_1 PF07690.16 ORY95249.1 - 2.7e-31 108.8 32.2 4.9e-24 84.9 2.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY95249.1 - 3.1e-28 98.9 10.2 5.8e-22 78.2 0.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter PI3_PI4_kinase PF00454.27 ORY95250.1 - 4.1e-40 138.2 0.0 4.3e-38 131.5 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY95250.1 - 7.1e-23 81.0 0.0 1.9e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Xpo1 PF08389.12 ORY95250.1 - 0.5 10.4 3.4 0.72 9.9 0.1 3.0 3 0 0 3 3 3 0 Exportin 1-like protein Snf7 PF03357.21 ORY95251.1 - 5.5e-12 45.6 17.4 5.5e-12 45.6 17.4 1.8 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 ORY95251.1 - 0.0056 16.6 4.7 0.0083 16.1 4.7 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TERB2 PF15101.6 ORY95252.1 - 0.094 12.8 7.6 0.22 11.5 7.6 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RNA_pol_Rbc25 PF08292.12 ORY95252.1 - 0.66 10.2 3.5 2.1 8.6 3.5 1.8 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF4834 PF16118.5 ORY95252.1 - 0.72 10.8 5.8 2.5 9.1 5.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 ORY95252.1 - 4.9 6.0 9.0 7.8 5.3 9.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) F-box-like PF12937.7 ORY95253.1 - 1.2e-06 28.3 1.1 4.8e-06 26.4 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY95253.1 - 9.7e-05 22.1 2.2 0.00017 21.4 0.0 2.6 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 ORY95253.1 - 0.0068 16.8 6.0 1.3 9.5 0.2 5.2 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY95253.1 - 1.5 8.6 5.6 5.9 6.7 1.1 3.8 3 1 1 4 4 4 0 Leucine rich repeat RhoGAP PF00620.27 ORY95254.1 - 2.3e-47 160.6 0.0 1.9e-46 157.7 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ORY95254.1 - 6.8e-15 55.1 1.3 1.3e-14 54.2 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3856 PF12968.7 ORY95254.1 - 0.052 13.6 0.7 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Acetyltransf_11 PF13720.6 ORY95254.1 - 0.073 13.5 0.0 1.1 9.8 0.0 3.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 LRS4 PF10422.9 ORY95254.1 - 0.2 11.2 4.0 0.32 10.5 3.7 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 CENP-T_C PF15511.6 ORY95255.1 - 2.4e-22 79.1 0.0 2.9e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY95255.1 - 1.4e-07 31.8 0.1 2e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 ORY95255.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated Histone PF00125.24 ORY95255.1 - 0.042 14.2 0.0 0.053 13.9 0.0 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY95255.1 - 0.06 13.6 0.0 0.077 13.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Proteasome PF00227.26 ORY95256.1 - 5.6e-52 176.0 0.0 7e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 ORY95256.1 - 1.2e-13 50.2 0.1 1.2e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal KH_1 PF00013.29 ORY95257.1 - 2e-46 155.7 7.5 9.8e-19 67.0 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY95257.1 - 9.8e-15 54.2 5.8 0.00021 21.0 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY95257.1 - 3.6e-11 42.8 8.0 8.5e-06 25.6 0.2 3.9 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 ORY95257.1 - 5.1e-05 23.3 4.4 0.43 10.7 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain CDC45 PF02724.14 ORY95257.1 - 1.8 6.8 6.8 2.6 6.2 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Reeler PF02014.16 ORY95258.1 - 1.8e-07 32.0 0.0 2.8e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Reeler domain DUF4448 PF14610.6 ORY95258.1 - 0.0094 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 ORY95258.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4381 PF14316.6 ORY95258.1 - 0.035 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) E1-E2_ATPase PF00122.20 ORY95259.1 - 5.3e-29 101.0 0.1 1.5e-28 99.5 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY95259.1 - 7.4e-08 32.9 4.7 0.0036 17.6 2.5 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY95259.1 - 1.2e-06 28.1 0.0 3.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY95259.1 - 0.0065 16.5 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Ldh_1_N PF00056.23 ORY95260.1 - 3.6e-35 121.1 1.7 5.6e-35 120.5 1.7 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORY95260.1 - 6.9e-20 71.6 0.0 1.4e-19 70.6 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 ORY95260.1 - 0.015 15.9 1.2 0.17 12.5 0.4 2.4 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 ORY95260.1 - 0.039 13.2 0.2 0.059 12.6 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 ORY95260.1 - 0.048 13.7 0.1 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ORY95260.1 - 0.056 13.1 0.6 0.22 11.2 0.6 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORY95260.1 - 0.1 12.5 0.5 0.17 11.8 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 ORY95260.1 - 0.13 11.9 2.9 0.17 11.4 1.2 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORY95260.1 - 0.56 9.8 3.0 4.4 6.8 3.0 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RNase_H PF00075.24 ORY95263.1 - 1.3e-08 35.1 0.0 5.9e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 RNase H CAML PF14963.6 ORY95263.1 - 0.21 11.7 0.4 0.3 11.2 0.4 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Amidohydro_2 PF04909.14 ORY95264.1 - 4.5e-29 102.1 0.4 5.6e-29 101.8 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Rad60-SLD_2 PF13881.6 ORY95265.1 - 9.3e-17 61.1 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY95265.1 - 0.022 14.5 0.0 0.074 12.8 0.0 1.9 3 0 0 3 3 3 0 Ubiquitin family DUF2407 PF10302.9 ORY95265.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Spc7 PF08317.11 ORY95267.1 - 0.00034 19.6 13.2 0.016 14.1 5.2 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein HOOK PF05622.12 ORY95267.1 - 0.0024 16.1 8.9 0.003 15.8 8.9 1.1 1 0 0 1 1 1 1 HOOK protein Filament PF00038.21 ORY95267.1 - 0.0063 16.1 13.7 0.025 14.2 5.4 2.2 1 1 1 2 2 2 2 Intermediate filament protein Golgin_A5 PF09787.9 ORY95267.1 - 0.0072 15.8 12.6 0.011 15.3 12.6 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 ATG16 PF08614.11 ORY95267.1 - 0.0072 16.6 13.5 0.13 12.4 5.9 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.6 ORY95267.1 - 0.0079 15.6 9.6 0.014 14.8 9.6 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 ORY95267.1 - 0.027 13.1 13.7 0.049 12.2 13.6 1.4 1 1 0 1 1 1 0 Macoilin family US22 PF02393.16 ORY95267.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 US22 like KxDL PF10241.9 ORY95267.1 - 0.14 12.4 11.9 0.85 9.9 2.0 3.2 2 1 2 4 4 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 ORY95267.1 - 0.18 11.8 8.8 0.89 9.6 1.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 ORY95267.1 - 0.23 10.4 10.0 0.39 9.6 10.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2203 PF09969.9 ORY95267.1 - 0.26 12.0 6.1 6.7 7.5 0.3 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec34 PF04136.15 ORY95267.1 - 0.45 10.4 7.9 2 8.3 0.3 2.6 1 1 1 2 2 2 0 Sec34-like family Fez1 PF06818.15 ORY95267.1 - 0.46 10.9 12.1 1.2 9.6 12.1 1.8 1 1 0 1 1 1 0 Fez1 DUF3450 PF11932.8 ORY95267.1 - 0.67 9.2 13.3 22 4.3 13.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 ORY95267.1 - 0.97 8.6 16.3 0.71 9.0 7.9 2.5 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 ORY95267.1 - 1.1 8.6 4.3 1.5 8.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tmemb_cc2 PF10267.9 ORY95267.1 - 1.1 8.4 17.2 0.066 12.3 4.6 2.8 1 1 2 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein TolA_bind_tri PF16331.5 ORY95267.1 - 1.1 9.3 10.7 3.6 7.7 0.4 3.1 2 1 0 2 2 2 0 TolA binding protein trimerisation ABC_tran_CTD PF16326.5 ORY95267.1 - 1.3 9.3 7.9 4.9 7.5 4.0 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 ORY95267.1 - 1.6 8.7 13.1 0.53 10.3 7.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 ORY95267.1 - 1.7 8.8 10.7 0.48 10.6 2.2 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 ORY95267.1 - 1.9 7.7 9.5 6.5 5.9 3.2 2.1 1 1 2 3 3 3 0 TMPIT-like protein CENP-H PF05837.12 ORY95267.1 - 2 8.8 13.1 0.58 10.6 3.0 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 ORY95267.1 - 2.2 8.6 12.8 3.8 7.8 1.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 ORY95267.1 - 2.6 8.1 14.5 2.4 8.2 6.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 ORY95267.1 - 2.9 8.7 6.8 30 5.4 0.8 3.0 1 1 2 3 3 3 0 Occludin homology domain Lebercilin PF15619.6 ORY95267.1 - 4.4 6.9 16.5 12 5.5 0.7 3.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF724 PF05266.14 ORY95267.1 - 6.6 6.5 11.5 57 3.5 10.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF948 PF06103.11 ORY95267.1 - 9.1 6.6 8.0 2.4 8.5 0.3 2.7 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Pro_isomerase PF00160.21 ORY95268.1 - 4.3e-49 166.8 0.5 5.3e-49 166.5 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mito_carr PF00153.27 ORY95269.1 - 1.3e-67 223.7 4.6 5.7e-24 83.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SUIM_assoc PF16619.5 ORY95270.1 - 0.56 10.3 20.8 0.69 10.0 0.2 4.2 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ATP-synt_E PF05680.12 ORY95271.1 - 1e-22 80.3 0.7 1.1e-22 80.2 0.7 1.0 1 0 0 1 1 1 1 ATP synthase E chain Cue1_U7BR PF18499.1 ORY95271.1 - 0.014 15.5 0.6 0.024 14.7 0.1 1.6 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 Gpr1_Fun34_YaaH PF01184.19 ORY95273.1 - 1.1e-34 119.9 18.3 1.3e-34 119.7 18.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PPTA PF01239.22 ORY95274.1 - 5.1e-14 51.5 21.4 3.8e-08 32.8 1.1 5.7 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat zf-C2H2_8 PF15909.5 ORY95274.1 - 0.14 12.4 0.1 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon SWIRM PF04433.17 ORY95275.1 - 4.6e-20 71.8 0.1 1.4e-19 70.2 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 ORY95275.1 - 3.6e-10 39.9 0.0 6.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 ORY95275.1 - 1.7e-08 34.3 6.5 1.7e-08 34.3 6.5 1.8 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 ORY95275.1 - 7.7e-07 29.3 0.1 2e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORY95275.1 - 0.013 15.3 5.0 0.027 14.3 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Chordopox_RPO7 PF05864.12 ORY95275.1 - 0.14 12.4 0.5 0.36 11.1 0.5 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) KAR9 PF08580.10 ORY95277.1 - 1.4e-12 47.0 1.2 1.4e-12 47.0 1.2 3.3 2 2 1 3 3 3 2 Yeast cortical protein KAR9 GAS2 PF02187.17 ORY95277.1 - 7.9e-07 29.1 1.3 2.1e-05 24.5 0.1 3.1 3 0 0 3 3 3 1 Growth-Arrest-Specific Protein 2 Domain CPSase_L_D2 PF02786.17 ORY95278.1 - 2.4e-79 265.7 0.2 4.5e-79 264.8 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ORY95278.1 - 1.2e-70 237.3 0.0 2e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ORY95278.1 - 1e-38 132.3 0.1 2.2e-38 131.2 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY95278.1 - 9.6e-32 109.3 0.0 2.5e-31 107.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ORY95278.1 - 3.7e-30 105.4 0.2 6.4e-30 104.6 0.2 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ORY95278.1 - 6.8e-18 64.3 3.6 2.4e-17 62.5 0.9 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY95278.1 - 5.5e-10 39.1 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY95278.1 - 1.5e-08 34.4 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY95278.1 - 7.1e-07 29.0 0.4 0.056 13.3 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 ORY95278.1 - 4e-06 27.5 1.2 0.036 14.8 0.2 3.4 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 ORY95278.1 - 2.7e-05 24.3 0.1 7.8e-05 22.8 0.0 1.8 2 0 0 2 2 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 ORY95278.1 - 0.0007 18.9 0.0 0.0041 16.4 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 ORY95278.1 - 0.0016 17.7 0.1 0.091 12.0 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 ORY95278.1 - 0.0019 17.9 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain DUF3182 PF11379.8 ORY95278.1 - 0.034 13.1 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) ATPgrasp_Ter PF15632.6 ORY95278.1 - 0.15 11.9 1.6 0.57 9.9 0.2 2.5 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon GCV_H PF01597.19 ORY95278.1 - 0.2 11.5 0.8 1.8 8.5 0.3 2.5 1 1 1 2 2 2 0 Glycine cleavage H-protein Pkinase PF00069.25 ORY95279.1 - 1.2e-35 123.2 0.0 1.3e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY95279.1 - 6.9e-31 107.5 0.0 8.4e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY95279.1 - 0.0016 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY95279.1 - 0.007 16.3 0.2 0.032 14.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY95279.1 - 0.021 14.2 0.2 0.028 13.8 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fn3-like PF14310.6 ORY95280.1 - 0.091 12.9 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 Fibronectin type III-like domain T4_neck-protein PF11649.8 ORY95280.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Virus neck protein ESSS PF10183.9 ORY95281.1 - 3e-07 30.6 0.1 3.8e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MatE PF01554.18 ORY95282.1 - 6.9e-41 139.6 21.5 1.2e-23 83.6 6.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 ORY95282.1 - 0.0016 18.5 6.6 0.0016 18.5 6.6 4.1 2 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 ORY95283.1 - 4.7e-15 55.6 18.4 5.9e-09 35.8 0.2 3.5 3 1 1 4 4 4 2 MatE Y_phosphatase2 PF03162.13 ORY95285.1 - 9.7e-57 191.1 0.0 1.1e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY95285.1 - 8.6e-07 29.2 0.0 1.9e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY95285.1 - 0.0022 17.8 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY95285.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Kelch_4 PF13418.6 ORY95286.1 - 1.3e-17 63.6 10.3 3.3e-06 27.0 0.2 5.1 3 2 1 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY95286.1 - 1e-13 50.9 0.1 0.00023 21.1 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 ORY95286.1 - 2.7e-12 46.5 10.7 0.00077 19.7 0.0 5.0 1 1 3 4 4 4 4 Kelch motif Kelch_2 PF07646.15 ORY95286.1 - 1.1e-08 34.7 3.2 0.027 14.4 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ORY95286.1 - 8.1e-08 32.4 14.1 0.0031 17.7 0.0 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY95286.1 - 5.5e-07 29.1 0.5 0.16 11.6 0.0 4.6 5 0 0 5 5 5 2 Kelch motif F5_F8_type_C PF00754.25 ORY95288.1 - 3e-05 24.1 0.0 5.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain TPR_8 PF13181.6 ORY95289.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY95289.1 - 0.11 12.7 0.0 15 6.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 ORY95289.1 - 0.17 12.4 3.9 0.9 10.1 1.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 ORY95291.1 - 1.6e-29 103.0 25.5 1.2e-28 100.0 26.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Tetraspanin PF00335.20 ORY95291.1 - 0.029 14.1 2.7 0.032 13.9 0.0 2.3 2 0 0 2 2 2 0 Tetraspanin family YesK PF14150.6 ORY95291.1 - 3.7 7.8 9.0 1.2 9.4 2.7 3.5 3 1 0 3 3 3 0 YesK-like protein RhoGAP PF00620.27 ORY95292.1 - 1.5e-39 135.3 0.0 1.9e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DEAD PF00270.29 ORY95293.1 - 7.1e-50 169.2 0.1 4.3e-48 163.4 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY95293.1 - 2.8e-23 82.4 0.1 2.1e-22 79.5 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 ORY95293.1 - 5e-22 77.9 3.0 5e-22 77.9 3.0 3.9 4 0 0 4 4 4 1 DBP10CT (NUC160) domain Cyto_heme_lyase PF01265.17 ORY95294.1 - 3.4e-59 200.8 14.2 1.4e-58 198.8 14.2 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Methyltr_RsmB-F PF01189.17 ORY95295.1 - 1.2e-27 96.9 0.0 7.5e-27 94.3 0.0 2.0 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY95295.1 - 0.012 15.7 0.0 0.018 15.2 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Xan_ur_permease PF00860.20 ORY95297.1 - 5.8e-60 203.0 38.6 1.2e-59 202.0 34.3 2.5 2 1 0 2 2 2 1 Permease family dCMP_cyt_deam_1 PF00383.23 ORY95298.1 - 1e-08 35.0 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 ORY95298.1 - 0.00018 21.6 0.1 0.00094 19.3 0.1 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase MafB19-deam PF14437.6 ORY95298.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase DIOX_N PF14226.6 ORY95299.1 - 2.9e-22 79.6 0.0 6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY95299.1 - 3.7e-15 56.3 0.0 6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA-synt_1 PF00133.22 ORY95300.1 - 7.9e-37 126.8 0.5 1.9e-17 62.7 0.3 3.7 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ORY95300.1 - 6.5e-16 58.1 0.1 3e-09 36.1 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORY95300.1 - 3.1e-13 50.0 0.3 7.1e-13 48.8 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORY95300.1 - 3.4e-08 33.2 0.0 9.8e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 ORY95300.1 - 0.018 14.5 2.9 0.29 10.6 0.1 3.1 3 0 0 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 RNB PF00773.19 ORY95301.1 - 8.1e-79 265.3 1.1 1.1e-78 264.9 0.0 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 ORY95301.1 - 1.9e-20 72.7 0.0 3.9e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORY95301.1 - 9.8e-16 57.9 0.1 9.8e-16 57.9 0.1 2.9 3 0 0 3 3 3 1 DIS3-like exonuclease 2 C terminal MCM PF00493.23 ORY95302.1 - 7.9e-101 335.8 0.2 1.3e-100 335.1 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY95302.1 - 2.4e-39 134.1 1.6 4.7e-39 133.1 1.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY95302.1 - 1.5e-26 92.7 1.9 3.6e-26 91.4 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 ORY95302.1 - 1.5e-25 89.5 0.1 1.5e-25 89.5 0.1 2.0 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 ORY95302.1 - 1.2e-13 51.5 0.3 5.8e-13 49.3 0.3 2.3 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY95302.1 - 4.5e-07 29.5 0.0 2.4e-06 27.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY95302.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY95302.1 - 0.00094 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 ORY95302.1 - 0.0011 18.9 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY95303.1 - 9.6e-97 320.5 0.0 2.7e-49 167.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY95303.1 - 6.1e-23 80.4 0.0 6e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORY95303.1 - 1.5e-15 57.3 0.0 3.9e-08 33.2 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY95303.1 - 3.6e-12 47.0 8.5 0.00039 20.9 0.0 5.1 3 2 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 ORY95303.1 - 1.1e-11 44.9 0.2 0.00025 21.1 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY95303.1 - 4e-11 43.3 0.0 8.9e-05 22.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY95303.1 - 1.3e-10 41.7 1.9 0.027 14.7 0.0 5.6 3 2 3 6 6 6 2 AAA domain AAA_33 PF13671.6 ORY95303.1 - 1.7e-10 41.2 0.0 0.00018 21.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORY95303.1 - 5.3e-09 35.7 0.0 0.00024 20.4 0.0 2.8 3 0 0 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 ORY95303.1 - 3e-08 34.0 0.0 0.011 16.1 0.0 2.9 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 ORY95303.1 - 2.3e-07 31.4 0.0 0.0086 16.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 ORY95303.1 - 4.2e-07 30.1 0.0 0.025 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORY95303.1 - 4.3e-07 29.4 0.1 0.041 13.2 0.0 3.1 4 0 0 4 4 3 2 Zeta toxin IstB_IS21 PF01695.17 ORY95303.1 - 6.6e-07 29.2 0.0 0.03 14.0 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 ORY95303.1 - 2.7e-06 27.4 0.5 0.072 13.0 0.0 3.9 5 0 0 5 5 4 2 NACHT domain Mg_chelatase PF01078.21 ORY95303.1 - 4.3e-06 26.3 0.2 0.054 12.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORY95303.1 - 5e-06 26.1 0.0 0.14 11.7 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region ABC_tran PF00005.27 ORY95303.1 - 6.9e-06 26.6 0.2 0.2 12.2 0.0 3.2 3 1 0 3 3 2 2 ABC transporter AAA_28 PF13521.6 ORY95303.1 - 7.9e-06 26.2 0.0 0.14 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ORY95303.1 - 9.4e-06 25.6 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ORY95303.1 - 1.1e-05 25.1 2.1 1.8 8.1 0.0 4.3 3 1 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 ORY95303.1 - 4.8e-05 23.1 0.0 0.2 11.3 0.0 3.5 4 0 0 4 4 4 1 Sigma-54 interaction domain DUF815 PF05673.13 ORY95303.1 - 6.8e-05 22.1 0.0 0.02 14.0 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 ORY95303.1 - 8.3e-05 22.5 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORY95303.1 - 9.8e-05 22.8 0.0 0.34 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 ORY95303.1 - 0.00016 21.8 0.0 0.04 14.1 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.15 ORY95303.1 - 0.00018 21.5 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_11 PF13086.6 ORY95303.1 - 0.0003 20.7 4.4 0.21 11.3 0.0 3.4 4 0 0 4 4 3 2 AAA domain ATPase PF06745.13 ORY95303.1 - 0.00032 20.1 0.0 1.1 8.6 0.0 3.4 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.18 ORY95303.1 - 0.00051 19.9 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ORY95303.1 - 0.00067 18.9 0.0 0.77 8.9 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 ORY95303.1 - 0.00099 18.9 0.0 0.31 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 ORY95303.1 - 0.0016 18.3 0.0 0.082 12.7 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein SKI PF01202.22 ORY95303.1 - 0.0017 18.5 0.2 2.7 8.1 0.0 2.9 3 0 0 3 3 2 1 Shikimate kinase ATPase_2 PF01637.18 ORY95303.1 - 0.0018 18.2 0.3 2.3 8.1 0.0 3.1 3 2 0 3 3 2 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 ORY95303.1 - 0.002 17.3 0.1 1.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 ORY95303.1 - 0.0026 17.7 0.0 3.7 7.4 0.0 3.2 3 1 0 3 3 2 0 NTPase Sigma54_activ_2 PF14532.6 ORY95303.1 - 0.0077 16.3 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 ORY95303.1 - 0.0082 16.0 0.0 5.6 6.7 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 ORY95303.1 - 0.0087 15.0 0.1 3.2 6.6 0.0 2.9 3 0 0 3 3 3 1 AFG1-like ATPase PhoH PF02562.16 ORY95303.1 - 0.012 15.1 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 ORY95303.1 - 0.018 15.3 2.5 1.5 9.1 0.1 3.1 3 1 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 ORY95303.1 - 0.022 14.4 0.0 6.6 6.3 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 ORY95303.1 - 0.026 14.3 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase PduV-EutP PF10662.9 ORY95303.1 - 0.03 14.0 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_9 PF14658.6 ORY95303.1 - 0.055 13.8 0.0 0.24 11.8 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Vps4_C PF09336.10 ORY95303.1 - 0.099 12.7 1.8 3.5 7.7 0.1 3.1 3 1 0 3 3 2 0 Vps4 C terminal oligomerisation domain DUF4543 PF15076.6 ORY95303.1 - 0.15 12.2 0.2 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) Hydin_ADK PF17213.3 ORY95303.1 - 1.7 8.9 0.0 1.7 8.9 0.0 3.6 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Ribosomal_L18A PF01775.17 ORY95304.1 - 2.2e-54 182.7 0.5 2.9e-54 182.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Put_DNA-bind_N PF06971.13 ORY95304.1 - 0.015 15.3 0.3 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus DNA_ligase_A_M PF01068.21 ORY95305.1 - 1.2e-47 162.3 0.0 3.4e-47 160.7 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY95305.1 - 3.5e-35 121.9 0.0 6.7e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 ORY95305.1 - 8.7e-17 61.3 0.0 1.2e-08 35.3 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 ORY95305.1 - 4.7e-15 56.0 0.0 1.6e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ORY95305.1 - 6.4e-10 39.6 0.0 2.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 RNA ligase BRCT PF00533.26 ORY95305.1 - 9.9e-08 32.3 0.0 1.9e-05 25.0 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 ORY95305.1 - 1.8e-05 24.7 0.1 6.7e-05 22.9 0.1 2.0 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.19 ORY95305.1 - 0.00052 19.9 0.2 0.034 14.0 0.0 3.3 3 1 0 3 3 3 1 mRNA capping enzyme, catalytic domain LIG3_BRCT PF16759.5 ORY95305.1 - 0.0027 18.0 0.1 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain DNA_ligase_OB_2 PF14743.6 ORY95305.1 - 0.036 14.1 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 DNA ligase OB-like domain Rep_fac_C PF08542.11 ORY95306.1 - 3.5e-23 81.8 0.1 1.7e-22 79.6 0.1 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORY95306.1 - 1.7e-13 50.6 0.0 4.9e-11 42.7 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 ORY95306.1 - 4.8e-13 49.7 0.1 8e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY95306.1 - 6.2e-06 26.3 0.0 9.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY95306.1 - 1.8e-05 25.2 0.0 0.00095 19.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY95306.1 - 0.00021 21.1 0.0 0.00051 19.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 ORY95306.1 - 0.00046 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 ORY95306.1 - 0.0014 18.9 0.2 1.8 8.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY95306.1 - 0.0017 17.9 0.1 0.0041 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY95306.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 ORY95306.1 - 0.0031 16.9 0.1 0.022 14.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 ORY95306.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 ORY95306.1 - 0.0041 17.0 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY95306.1 - 0.0089 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 ORY95306.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ORY95306.1 - 0.013 14.9 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein MeaB PF03308.16 ORY95306.1 - 0.041 12.9 0.1 0.08 11.9 0.1 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 ORY95306.1 - 0.042 13.3 0.1 0.084 12.3 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 ORY95306.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 ORY95306.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 ORY95306.1 - 0.14 12.1 0.2 1.8 8.4 0.1 2.5 2 1 0 3 3 3 0 NTPase GDP_Man_Dehyd PF16363.5 ORY95308.1 - 9.3e-60 202.8 0.0 1.2e-59 202.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY95308.1 - 3.6e-54 183.8 0.0 4.6e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY95308.1 - 2.4e-17 63.0 0.0 3.9e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY95308.1 - 5.2e-17 61.7 0.1 7.8e-17 61.2 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ORY95308.1 - 2.9e-11 43.2 0.2 4.9e-11 42.5 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ORY95308.1 - 1.3e-09 38.2 0.0 8.8e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY95308.1 - 3.8e-09 36.1 0.0 5.4e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORY95308.1 - 3.8e-09 36.7 0.1 6.3e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 ORY95308.1 - 5.2e-08 32.7 0.2 1.1e-05 25.1 0.2 2.2 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 ORY95308.1 - 8.9e-05 21.8 0.0 0.01 15.0 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein UDPG_MGDP_dh_N PF03721.14 ORY95308.1 - 0.0011 18.6 0.1 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 ORY95308.1 - 0.0045 17.2 0.1 0.01 16.1 0.1 1.7 2 0 0 2 2 1 1 TrkA-N domain adh_short_C2 PF13561.6 ORY95308.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 ORY95308.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY95308.1 - 0.037 14.3 0.1 0.084 13.1 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 ORY95308.1 - 0.041 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORY95308.1 - 0.044 14.2 0.1 0.089 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Arylsulfotran_2 PF14269.6 ORY95308.1 - 0.073 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) DNApol_Exo PF18136.1 ORY95309.1 - 4.9e-106 354.0 0.0 1.1e-105 352.9 0.0 1.6 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 ORY95309.1 - 2.6e-49 168.3 0.0 5.8e-49 167.1 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family A Glyco_hydro_46 PF01374.18 ORY95309.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 DNA_pol_A_exo1 PF01612.20 ORY95309.1 - 0.084 12.6 0.0 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease SNARE_assoc PF09335.11 ORY95310.1 - 7.2e-17 62.0 10.8 9.5e-17 61.6 9.2 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DDDD PF10161.9 ORY95310.1 - 0.14 12.0 0.1 0.39 10.5 0.1 1.8 1 0 0 1 1 1 0 Putative mitochondrial precursor protein F-box-like PF12937.7 ORY95311.1 - 7.8e-05 22.5 3.2 0.00015 21.6 0.1 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 ORY95311.1 - 0.68 10.4 9.8 12 6.5 0.0 5.0 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) ARS2 PF04959.13 ORY95312.1 - 0.038 14.4 0.3 0.038 14.4 0.3 2.1 2 0 0 2 2 2 0 Arsenite-resistance protein 2 3-PAP PF12578.8 ORY95315.1 - 0.15 11.8 0.2 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 Myotubularin-associated protein PIN_4 PF13638.6 ORY95317.1 - 1.8e-23 83.3 2.1 3.6e-23 82.3 0.0 2.5 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 ORY95317.1 - 1.2e-08 34.8 0.1 7.3e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain IL28A PF15177.6 ORY95317.1 - 0.28 11.0 6.5 0.13 12.1 0.2 2.7 2 0 0 2 2 2 0 Interleukin-28A Astro_capsid_N PF03115.14 ORY95317.1 - 1.5 7.4 6.4 2.4 6.7 6.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor EST1 PF10374.9 ORY95317.1 - 1.6 9.4 8.5 0.39 11.4 0.6 3.5 2 1 0 2 2 2 0 Telomerase activating protein Est1 Ndc1_Nup PF09531.10 ORY95317.1 - 1.8 7.2 9.9 3 6.4 9.9 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 ORY95317.1 - 3.1 7.3 15.6 6.4 6.3 15.6 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 ORY95317.1 - 7 6.5 28.7 0.24 11.4 22.1 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Utp12 PF04003.12 ORY95318.1 - 6.7e-24 84.3 0.3 1.1e-23 83.5 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 ORY95318.1 - 3.3e-06 27.7 0.0 0.0011 19.7 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY95318.1 - 4.4e-05 23.7 0.7 11 6.5 0.0 4.3 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain RRN3 PF05327.11 ORY95318.1 - 0.12 10.9 4.6 0.19 10.2 4.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Bromodomain PF00439.25 ORY95319.1 - 1.7e-135 441.4 4.8 6.5e-23 80.6 0.0 6.7 6 0 0 6 6 6 6 Bromodomain Peptidase_M1 PF01433.20 ORY95319.1 - 2.5e-05 24.0 0.0 5.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY95319.1 - 0.066 13.4 0.2 7.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain WW PF00397.26 ORY95320.1 - 1.5e-05 24.9 12.4 1.5e-05 24.9 12.4 2.8 3 0 0 3 3 3 1 WW domain SDA1 PF05285.12 ORY95320.1 - 0.0018 17.8 24.0 0.0022 17.5 24.0 1.1 1 0 0 1 1 1 1 SDA1 Zip PF02535.22 ORY95320.1 - 0.96 8.6 6.5 1.3 8.2 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UCH PF00443.29 ORY95321.1 - 4.8e-59 200.0 0.0 9.3e-59 199.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY95321.1 - 2.1e-28 99.9 5.9 9.6e-23 81.3 1.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORY95321.1 - 0.013 14.9 2.2 0.013 14.9 2.2 2.8 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DnaJ PF00226.31 ORY95322.1 - 3.9e-19 68.5 1.3 5.7e-19 68.0 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain Dppa2_A PF14049.6 ORY95322.1 - 0.075 13.2 0.1 0.14 12.3 0.0 1.5 1 1 1 2 2 2 0 Dppa2/4 conserved region in higher vertebrates eIF3g PF12353.8 ORY95323.1 - 6.3e-46 155.8 4.1 1.1e-45 155.0 4.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 ORY95323.1 - 6.9e-20 70.7 0.2 2.4e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY95323.1 - 3.3e-05 23.7 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_8 PF11835.8 ORY95323.1 - 0.004 17.3 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_5 PF13893.6 ORY95323.1 - 0.039 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 ORY95323.1 - 0.074 13.4 1.3 0.15 12.4 0.1 2.1 2 1 1 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 NSP11 PF06471.12 ORY95323.1 - 0.084 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 NSP11 Ank_2 PF12796.7 ORY95324.1 - 2.4e-12 47.3 0.7 3.9e-10 40.2 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) TIG PF01833.24 ORY95324.1 - 6.2e-12 45.4 0.1 9.6e-11 41.6 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.30 ORY95324.1 - 7.2e-09 35.7 0.2 2.6e-05 24.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORY95324.1 - 1.4e-08 35.1 0.0 6.9e-06 26.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY95324.1 - 2.2e-06 27.9 0.1 0.00055 20.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY95324.1 - 0.0029 18.0 0.1 2.1 9.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Asp_protease PF09668.10 ORY95325.1 - 1.8e-15 56.8 0.1 3.1e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 ORY95325.1 - 1.7e-11 43.7 0.1 3.2e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 ORY95325.1 - 1.4e-05 24.8 4.4 1.4e-05 24.8 4.4 2.6 2 1 1 3 3 3 1 XPC-binding domain Rad60-SLD PF11976.8 ORY95325.1 - 1.4e-05 24.8 0.5 4e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like gag-asp_proteas PF13975.6 ORY95325.1 - 5.3e-05 23.7 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Ubiquitin_2 PF14560.6 ORY95325.1 - 0.00084 19.8 0.0 0.0027 18.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain RVP PF00077.20 ORY95325.1 - 0.00096 19.4 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 ORY95325.1 - 0.0096 16.5 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Bep_C_terminal PF17841.1 ORY95325.1 - 0.085 13.1 1.6 0.3 11.3 1.0 2.0 1 1 1 2 2 2 0 BID domain of Bartonella effector protein (Bep) IF-2B PF01008.17 ORY95326.1 - 1.9e-72 243.8 3.2 2.3e-72 243.6 3.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peripla_BP_1 PF00532.21 ORY95326.1 - 2.2e-05 24.0 1.2 0.089 12.2 0.1 2.8 2 2 1 3 3 3 2 Periplasmic binding proteins and sugar binding domain of LacI family TFIIS_M PF07500.14 ORY95327.1 - 2.1e-25 89.4 3.6 2.1e-25 89.4 3.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 ORY95327.1 - 1.3e-15 57.6 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 ORY95327.1 - 2.2e-10 40.2 13.9 5.2e-10 39.1 13.9 1.7 1 0 0 1 1 1 1 PHD-finger Ecl1 PF12855.7 ORY95327.1 - 0.01 17.0 19.7 0.01 17.0 19.7 3.9 3 2 0 3 3 3 0 ECL1/2/3 zinc binding proteins Toxin_2 PF00451.19 ORY95328.1 - 0.0076 16.5 12.8 0.012 15.9 1.9 2.5 2 0 0 2 2 2 2 Scorpion short toxin, BmKK2 vMSA PF00695.19 ORY95328.1 - 0.47 9.5 3.7 0.51 9.4 3.7 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus HLH PF00010.26 ORY95331.1 - 6.6e-13 48.4 0.6 1.7e-12 47.1 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nmad5 PF18757.1 ORY95331.1 - 0.057 13.6 0.2 0.095 12.9 0.2 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 ACP_PD PF04336.12 ORY95331.1 - 0.068 13.6 0.8 0.17 12.3 0.8 1.6 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase ZapB PF06005.12 ORY95331.1 - 0.13 12.7 0.4 0.13 12.7 0.4 2.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF4355 PF14265.6 ORY95331.1 - 0.14 12.4 2.0 0.32 11.2 1.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) HALZ PF02183.18 ORY95331.1 - 0.82 9.9 4.6 0.41 10.9 0.9 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper SLX9 PF15341.6 ORY95331.1 - 9.2 6.7 12.2 1.9 8.9 7.2 2.3 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Sld5 PF05916.11 ORY95332.1 - 6.4e-05 23.4 0.4 9.2e-05 22.9 0.4 1.3 1 0 0 1 1 1 1 GINS complex protein UQ_con PF00179.26 ORY95333.1 - 1.1e-18 67.3 0.0 1.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY95333.1 - 0.082 13.2 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain AraC_binding PF02311.19 ORY95333.1 - 0.15 12.0 0.4 0.25 11.3 0.3 1.4 1 1 0 1 1 1 0 AraC-like ligand binding domain ALG11_N PF15924.5 ORY95334.1 - 1.8e-91 305.9 0.6 2.4e-91 305.5 0.6 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 ORY95334.1 - 1.5e-27 96.2 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY95334.1 - 9.3e-13 48.8 0.0 1.9e-12 47.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORY95334.1 - 0.04 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Oxidored_nitro PF00148.19 ORY95334.1 - 0.063 12.0 0.0 3 6.5 0.0 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Glyco_transf_4 PF13439.6 ORY95334.1 - 0.086 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RhoGEF PF00621.20 ORY95338.1 - 3.3e-38 131.7 2.8 6.6e-38 130.8 2.8 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 ORY95338.1 - 1.7e-31 108.3 0.4 3.5e-31 107.3 0.4 1.6 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 ORY95338.1 - 3.3e-21 75.8 1.5 7e-21 74.7 1.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 ORY95338.1 - 2.1e-16 59.6 0.1 5.6e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 ORY95338.1 - 0.008 16.7 1.4 0.019 15.5 0.4 2.1 2 0 0 2 2 2 1 PH domain SKA2 PF16740.5 ORY95338.1 - 0.027 14.3 1.1 0.061 13.1 0.2 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 P_C PF06640.11 ORY95338.1 - 7.4 6.7 7.6 0.53 10.4 1.6 2.1 2 0 0 2 2 2 0 P protein C-terminus RRM_1 PF00076.22 ORY95340.1 - 9.2e-10 38.2 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 ORY95340.1 - 0.0042 17.1 2.9 0.0042 17.1 2.9 2.9 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Ndc1_Nup PF09531.10 ORY95340.1 - 0.23 10.1 7.3 0.31 9.7 7.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 ORY95340.1 - 1.4 7.7 7.4 2 7.2 7.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 ORY95340.1 - 2.5 7.9 5.8 5.8 6.7 5.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAXIP1_C PF15364.6 ORY95340.1 - 10 6.5 12.8 1.5 9.1 8.5 1.7 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Acyl_transf_3 PF01757.22 ORY95341.1 - 0.0012 18.0 3.3 0.0014 17.8 3.3 1.1 1 0 0 1 1 1 1 Acyltransferase family 7TMR-DISM_7TM PF07695.11 ORY95341.1 - 0.052 13.4 5.3 0.069 13.0 5.3 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF4131 PF13567.6 ORY95341.1 - 0.058 13.0 2.1 0.08 12.6 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HLH PF00010.26 ORY95343.1 - 1.4e-14 53.8 1.7 2.9e-14 52.7 1.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3245 PF11595.8 ORY95343.1 - 8.1 6.9 18.5 28 5.2 13.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) UVR PF02151.19 ORY95345.1 - 0.0068 16.1 3.4 0.0068 16.1 3.4 2.5 2 0 0 2 2 2 1 UvrB/uvrC motif TRAF6_Z2 PF18048.1 ORY95345.1 - 0.053 13.6 0.0 0.053 13.6 0.0 2.7 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 FliD_C PF07195.12 ORY95345.1 - 0.24 10.8 5.2 2.8 7.3 0.1 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus zf_UBZ PF18439.1 ORY95345.1 - 0.43 10.2 8.8 0.67 9.6 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger XAF1_C PF18608.1 ORY95345.1 - 1.1 8.9 3.9 1.9 8.1 2.6 2.1 1 1 1 2 2 2 0 XIAP-associated factor 1 C-terminal domain zf-TRAF PF02176.18 ORY95345.1 - 2.9 8.7 10.5 0.22 12.2 4.7 2.3 2 1 1 3 3 3 0 TRAF-type zinc finger Fungal_trans PF04082.18 ORY95346.1 - 6.2e-19 68.0 3.7 6.2e-19 68.0 3.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY95346.1 - 1.9e-10 40.7 6.5 3.3e-10 39.9 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydin_ADK PF17213.3 ORY95346.1 - 0.45 10.8 16.8 0.53 10.5 0.4 3.8 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain E2F_TDP PF02319.20 ORY95347.1 - 2.2e-24 85.3 0.1 4.2e-23 81.2 0.1 2.4 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 ORY95347.1 - 1.2e-06 28.5 0.3 4.8e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 Transcription factor DP SR-25 PF10500.9 ORY95347.1 - 0.00032 20.4 13.3 0.00063 19.4 13.3 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 ORY95347.1 - 0.0047 17.7 3.4 0.011 16.6 3.4 1.6 1 0 0 1 1 1 1 Chorion family 2 PNISR PF15996.5 ORY95347.1 - 0.57 10.4 9.5 0.16 12.2 4.4 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Cwf_Cwc_15 PF04889.12 ORY95347.1 - 2.1 8.0 12.3 0.15 11.8 4.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein IMUP PF15761.5 ORY95347.1 - 2.3 9.0 16.7 10 6.9 16.7 2.1 1 1 0 1 1 1 0 Immortalisation up-regulated protein NuDC PF16273.5 ORY95347.1 - 9.6 6.8 12.1 0.17 12.4 4.4 2.1 2 0 0 2 2 2 0 Nuclear distribution C domain CBS PF00571.28 ORY95349.1 - 3e-29 101.2 2.1 4.8e-08 33.3 0.0 4.6 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 ORY95349.1 - 0.0036 17.2 4.4 0.024 14.6 4.4 2.3 1 1 0 1 1 1 1 PB1 domain TRH PF05438.12 ORY95349.1 - 0.12 12.1 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) DOR PF14839.6 ORY95349.1 - 0.14 12.1 2.4 0.26 11.2 2.4 1.5 1 0 0 1 1 1 0 DOR family Ribosomal_60s PF00428.19 ORY95349.1 - 0.43 11.2 15.7 1.2 9.8 15.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ras PF00071.22 ORY95351.1 - 4.4e-50 169.4 0.0 5.5e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY95351.1 - 2e-21 76.4 0.0 2.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY95351.1 - 7.2e-05 22.3 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY95351.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORY95351.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Secretogranin_V PF05281.11 ORY95351.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) RGS PF00615.19 ORY95352.1 - 1.3e-12 48.1 0.1 2.5e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DPM2 PF07297.12 ORY95352.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) SET PF00856.28 ORY95353.1 - 0.04 14.3 0.7 0.12 12.7 0.6 2.2 1 1 0 1 1 1 0 SET domain Fis1_TPR_C PF14853.6 ORY95354.1 - 7.4e-22 77.2 0.2 1.1e-21 76.6 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ORY95354.1 - 6e-15 54.6 0.0 1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 ORY95354.1 - 0.16 12.2 0.3 0.16 12.2 0.3 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 ORY95355.1 - 6.9e-10 39.1 4.1 6.9e-10 39.1 4.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORY95355.1 - 2.4e-08 34.1 2.7 1.1e-07 32.1 1.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY95355.1 - 8.3e-08 32.0 4.0 8.3e-08 32.0 4.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY95355.1 - 2.3e-06 27.4 6.8 3.1e-06 27.0 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY95355.1 - 4.4e-06 26.3 3.0 4.4e-06 26.3 3.0 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY95355.1 - 0.00011 22.1 2.9 0.00011 22.1 2.9 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 ORY95355.1 - 0.00029 20.9 0.5 0.00095 19.3 0.5 1.9 1 1 0 1 1 1 1 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 ORY95355.1 - 0.00039 20.0 1.3 0.0008 19.0 1.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ORY95355.1 - 0.0036 17.2 1.6 0.0036 17.2 1.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-HC5HC2H PF13771.6 ORY95355.1 - 0.0067 16.7 0.4 0.019 15.2 0.1 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY95355.1 - 0.01 15.7 2.0 0.01 15.7 2.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY95355.1 - 0.013 15.6 0.2 0.029 14.4 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY95355.1 - 0.13 12.4 3.2 0.35 11.1 3.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 ORY95355.1 - 1.5 8.8 5.9 0.38 10.7 2.0 1.9 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 ORY95355.1 - 2.2 8.5 6.1 0.26 11.4 1.7 1.7 2 0 0 2 2 1 0 KIAA1045 RING finger Sulfotransfer_4 PF17784.1 ORY95356.1 - 8.7e-62 208.7 0.0 1.2e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95356.1 - 1.1e-07 32.5 0.2 0.00024 21.6 0.0 2.8 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 ORY95358.1 - 9.5e-41 140.0 0.1 1.1e-40 139.8 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95358.1 - 0.022 15.1 0.0 0.052 13.9 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase family Peptidase_S9 PF00326.21 ORY95359.1 - 3.8e-41 140.9 0.0 6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 ORY95359.1 - 1.2e-36 126.4 0.3 1.7e-36 125.9 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Esterase PF00756.20 ORY95359.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 ORY95359.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY95359.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 tRNA_int_end_N2 PF12928.7 ORY95360.1 - 2e-07 31.1 0.0 4.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term zf-CCHC PF00098.23 ORY95361.1 - 6e-19 67.2 45.1 8.2e-08 32.0 3.4 5.8 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 ORY95361.1 - 0.0051 16.5 26.8 0.09 12.5 1.2 4.6 5 0 0 5 5 5 3 Zinc knuckle RR_TM4-6 PF06459.12 ORY95361.1 - 0.0078 16.1 1.6 0.0095 15.8 1.6 1.0 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 zf-CCHC_6 PF15288.6 ORY95361.1 - 0.025 14.4 2.4 0.025 14.4 2.4 5.2 4 2 1 5 5 5 0 Zinc knuckle FAM176 PF14851.6 ORY95361.1 - 0.045 13.4 3.4 0.058 13.0 3.4 1.2 1 0 0 1 1 1 0 FAM176 family DUF3245 PF11595.8 ORY95361.1 - 0.071 13.6 4.8 0.093 13.2 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Protamine_P2 PF00841.19 ORY95361.1 - 0.077 13.5 3.2 0.12 12.8 3.2 1.4 1 0 0 1 1 1 0 Sperm histone P2 zf-CCHC_3 PF13917.6 ORY95361.1 - 0.19 11.7 0.1 0.19 11.7 0.1 4.6 3 1 0 3 3 2 0 Zinc knuckle Pox_Ag35 PF03286.14 ORY95361.1 - 0.41 10.4 5.2 0.53 10.1 5.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 ORY95361.1 - 1.2 7.8 2.2 1.3 7.7 2.2 1.0 1 0 0 1 1 1 0 Presenilin GRP PF07172.11 ORY95361.1 - 3.9 8.2 12.5 9.3 7.0 12.5 1.6 1 1 0 1 1 1 0 Glycine rich protein family Zip PF02535.22 ORY95361.1 - 10 5.3 5.3 12 5.0 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Kelch_4 PF13418.6 ORY95362.1 - 6.2e-15 54.9 12.3 7.3e-06 25.9 0.0 6.6 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY95362.1 - 3.1e-13 49.1 0.8 0.019 14.5 0.0 6.6 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 ORY95362.1 - 2.6e-12 46.6 9.9 0.0051 17.1 0.0 6.5 4 1 2 6 6 6 4 Kelch motif Kelch_5 PF13854.6 ORY95362.1 - 5.6e-12 45.4 11.5 0.00048 20.1 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 ORY95362.1 - 8.8e-10 38.6 12.7 0.2 12.0 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY95362.1 - 5.9e-08 32.4 0.6 0.8 9.8 0.0 5.9 6 0 0 6 6 6 2 Kelch motif ASC PF00858.24 ORY95362.1 - 0.059 12.3 0.0 0.059 12.3 0.0 2.9 2 1 1 3 3 3 0 Amiloride-sensitive sodium channel SLC3A2_N PF16028.5 ORY95362.1 - 0.15 11.7 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Plug_translocon PF10559.9 ORY95362.1 - 0.3 10.9 1.4 7.2 6.5 1.3 2.6 2 0 0 2 2 2 0 Plug domain of Sec61p Septin PF00735.18 ORY95363.1 - 1.9e-112 375.1 0.4 2.9e-112 374.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY95363.1 - 7.3e-08 32.5 0.1 2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY95363.1 - 0.0011 18.6 0.1 0.0035 16.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY95363.1 - 0.0074 16.2 1.8 0.013 15.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 ORY95363.1 - 0.008 15.5 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family tRNA_synthFbeta PF17759.1 ORY95363.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Rep_3 PF01051.21 ORY95363.1 - 0.08 12.7 1.2 1 9.2 0.1 2.7 1 1 1 2 2 2 0 Initiator Replication protein Dynamin_N PF00350.23 ORY95363.1 - 0.082 13.0 5.3 1.6 8.7 0.0 3.2 2 1 1 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 ORY95363.1 - 0.1 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ORY95363.1 - 0.16 12.5 6.5 2.5 8.6 5.4 2.2 2 0 0 2 2 2 0 AAA domain DUF4140 PF13600.6 ORY95363.1 - 1 9.9 6.4 49 4.5 5.0 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Carn_acyltransf PF00755.20 ORY95364.1 - 9.9e-214 711.3 0.1 1.1e-213 711.1 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sel1 PF08238.12 ORY95365.1 - 1.6e-23 82.6 26.5 1.3e-09 38.4 0.6 7.7 8 0 0 8 8 8 5 Sel1 repeat TPR_1 PF00515.28 ORY95365.1 - 0.0007 19.3 6.7 0.0052 16.5 1.6 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY95365.1 - 0.0062 16.7 4.8 0.12 12.7 0.7 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY95365.1 - 0.012 16.0 0.5 1 9.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY95365.1 - 0.017 15.2 12.3 0.041 14.0 1.9 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY95365.1 - 0.021 15.1 0.1 0.058 13.7 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.6 ORY95365.1 - 0.028 14.7 4.5 0.052 13.9 0.9 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 ORY95365.1 - 2.1 7.7 5.9 1.9 7.9 2.8 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP DIL PF01843.19 ORY95366.1 - 7e-28 96.9 5.7 1.9e-27 95.6 5.7 1.8 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 ORY95366.1 - 1e-06 29.2 0.0 2.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY95366.1 - 7.2e-05 23.1 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 ORY95366.1 - 9.4e-05 22.6 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY95366.1 - 0.00089 19.8 0.0 0.0026 18.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY95366.1 - 0.032 14.8 0.0 0.2 12.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat DUF1168 PF06658.12 ORY95367.1 - 6.7e-41 139.3 29.4 6.7e-41 139.3 29.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) DUF4407 PF14362.6 ORY95367.1 - 0.36 10.1 8.1 0.37 10.1 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 ORY95367.1 - 1.9 7.2 13.4 1.7 7.3 13.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPL5 PF18168.1 ORY95367.1 - 4.5 6.5 12.2 6.3 6.0 12.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 V_ATPase_I PF01496.19 ORY95367.1 - 5.1 4.9 11.2 5.5 4.8 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCM_bind PF09739.9 ORY95367.1 - 6 5.2 13.4 6 5.2 13.4 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MCM3AP_GANP PF16769.5 ORY95367.1 - 7.9 4.6 12.4 10 4.2 12.4 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP XPG_N PF00752.17 ORY95368.1 - 3.2e-33 114.2 0.0 1.3e-32 112.3 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 ORY95368.1 - 8.6e-27 93.3 0.0 2.2e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 ORY95368.1 - 1.1e-05 25.1 0.0 1.1e-05 25.1 0.0 2.4 3 0 0 3 3 3 1 XPG domain containing BicD PF09730.9 ORY95369.1 - 0.025 13.0 3.4 0.04 12.4 3.4 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF1759 PF03564.15 ORY95369.1 - 0.26 11.2 6.0 13 5.7 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) HAUS-augmin3 PF14932.6 ORY95369.1 - 2.5 7.6 6.4 0.68 9.5 2.8 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4472 PF14739.6 ORY95369.1 - 4 8.2 6.2 4.4 8.1 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 ORY95369.1 - 5.7 7.5 13.0 0.5 10.9 7.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region SRPRB PF09439.10 ORY95370.1 - 9.3e-52 175.1 0.0 1.1e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 ORY95370.1 - 4.3e-22 78.4 0.0 5.6e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY95370.1 - 8.7e-10 38.5 1.1 3e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY95370.1 - 1.3e-08 34.9 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY95370.1 - 1.3e-08 34.4 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY95370.1 - 1.4e-07 31.8 0.0 3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY95370.1 - 5e-07 29.5 0.1 7.5e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 ORY95370.1 - 7.4e-07 28.8 0.5 3.5e-06 26.6 0.5 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ORY95370.1 - 3.2e-06 27.1 0.4 1.1e-05 25.4 0.1 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 ORY95370.1 - 3.7e-05 23.0 0.8 0.1 11.7 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 ORY95370.1 - 0.00085 19.3 0.2 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase DLIC PF05783.11 ORY95370.1 - 0.02 13.7 0.1 0.63 8.8 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Insulin_TMD PF17870.1 ORY95370.1 - 0.074 13.1 0.4 0.17 12.0 0.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PPV_E1_C PF00519.17 ORY95370.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase MMR_HSR1_Xtn PF16897.5 ORY95370.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA PF00004.29 ORY95370.1 - 0.17 12.3 0.2 0.61 10.5 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-RING_2 PF13639.6 ORY95371.1 - 4.4e-12 46.1 8.9 7.2e-12 45.4 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY95371.1 - 7.4e-08 32.0 9.3 1.4e-07 31.2 9.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY95371.1 - 1.3e-07 31.4 9.3 2.2e-07 30.6 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY95371.1 - 2.7e-07 30.4 6.7 2.7e-07 30.4 6.7 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY95371.1 - 1.3e-05 25.3 11.2 8.6e-05 22.8 10.1 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY95371.1 - 1.6e-05 24.9 3.8 9.9e-05 22.3 2.5 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY95371.1 - 1.6e-05 24.8 8.6 5.7e-05 23.1 8.8 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY95371.1 - 2.6e-05 24.1 4.5 4.1e-05 23.5 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY95371.1 - 7.7e-05 22.5 4.0 7.7e-05 22.5 4.0 1.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY95371.1 - 0.01 15.7 8.5 0.47 10.4 9.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY95371.1 - 0.023 14.8 6.8 0.061 13.5 6.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY95371.1 - 0.042 13.7 6.6 0.26 11.2 6.8 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 ORY95371.1 - 0.13 11.9 7.7 0.54 9.9 7.7 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORY95371.1 - 0.47 10.7 9.1 8.7 6.6 9.1 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 ORY95371.1 - 0.62 9.9 4.5 1.1 9.2 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 ORY95371.1 - 1.4 8.7 6.9 12 5.8 7.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pil1 PF13805.6 ORY95372.1 - 1.5e-18 67.2 0.0 2.6e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 ATP_bind_1 PF03029.17 ORY95374.1 - 3.8e-83 279.0 0.0 4.4e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ORY95374.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 ORY95374.1 - 0.0044 17.2 0.0 0.011 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY95374.1 - 0.0051 15.8 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORY95374.1 - 0.018 14.8 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY95374.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY95374.1 - 0.05 14.0 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 ORY95374.1 - 0.056 13.4 0.0 0.98 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 ORY95374.1 - 0.063 13.3 0.0 0.097 12.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 ORY95374.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 ORY95374.1 - 0.089 12.4 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 ORY95374.1 - 0.092 12.7 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 ORY95374.1 - 0.094 12.8 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 ORY95374.1 - 0.16 12.4 0.2 0.6 10.5 0.2 2.0 1 0 0 1 1 1 0 AAA domain ATE_C PF04377.15 ORY95375.1 - 4.6e-51 173.0 3.6 4.6e-51 173.0 3.6 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 ORY95375.1 - 1.3e-31 108.8 4.5 1.1e-29 102.6 3.9 2.4 2 0 0 2 2 2 2 Arginine-tRNA-protein transferase, N terminus Cnd3 PF12719.7 ORY95376.1 - 1.3e-82 277.3 8.4 1.3e-82 277.3 8.4 3.0 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 ORY95376.1 - 2.2e-09 37.6 3.9 2.3e-05 24.7 0.4 4.2 2 1 1 3 3 3 3 HEAT repeats Cnd1 PF12717.7 ORY95376.1 - 5.3e-08 33.1 5.3 0.011 15.8 0.2 5.2 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY95376.1 - 1.2e-05 25.1 9.2 0.46 10.9 0.1 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 ORY95376.1 - 7.4e-05 23.2 0.2 5.3 7.7 0.0 4.7 4 0 0 4 4 4 2 HEAT-like repeat Cyt-b5 PF00173.28 ORY95377.1 - 2.4e-11 43.6 0.1 2.7e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aldedh PF00171.22 ORY95378.1 - 3.9e-167 556.4 0.6 4.5e-167 556.2 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LSM PF01423.22 ORY95378.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 LSM domain Vac_ImportDeg PF09783.9 ORY95379.1 - 8.4e-57 191.5 0.9 1.2e-56 191.0 0.9 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein RRM_1 PF00076.22 ORY95380.1 - 1.5e-15 56.7 0.0 2.8e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ORY95380.1 - 2.2e-08 34.5 8.1 2.2e-08 34.5 8.1 3.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 FCH PF00611.23 ORY95381.1 - 9.4e-11 41.9 0.1 2.6e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 ORY95381.1 - 1.3e-10 40.7 0.0 2.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY95381.1 - 1.8e-08 34.1 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY95381.1 - 8.3e-08 31.8 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 ORY95381.1 - 0.028 14.1 2.5 0.062 13.0 2.1 1.8 1 1 0 1 1 1 0 BAR domain of APPL family DUF1699 PF08004.11 ORY95381.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Phage_TAC_8 PF10666.9 ORY95381.1 - 0.16 12.2 0.4 0.61 10.4 0.1 2.0 1 1 1 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 FAM76 PF16046.5 ORY95381.1 - 0.27 10.5 3.4 0.89 8.8 3.4 1.9 1 0 0 1 1 1 0 FAM76 protein Thioredoxin PF00085.20 ORY95382.1 - 5e-18 65.0 0.0 6.6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORY95382.1 - 0.00092 18.6 0.0 0.0015 18.0 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY95382.1 - 0.0012 19.3 0.1 0.0023 18.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORY95382.1 - 0.0034 17.5 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 ORY95382.1 - 0.0087 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 ORY95382.1 - 0.0089 16.3 0.1 0.073 13.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like RabGAP-TBC PF00566.18 ORY95383.1 - 3.4e-50 170.7 0.1 3.4e-50 170.7 0.1 1.9 3 0 0 3 3 2 1 Rab-GTPase-TBC domain DUF4201 PF13870.6 ORY95383.1 - 0.0038 17.0 7.9 0.0038 17.0 7.9 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) UPF0242 PF06785.11 ORY95383.1 - 0.0059 16.7 14.8 0.0059 16.7 14.8 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 ORY95383.1 - 0.0069 16.5 7.9 0.0069 16.5 7.9 3.0 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 She9_MDM33 PF05546.11 ORY95383.1 - 0.019 14.8 1.8 0.019 14.8 1.8 2.8 3 0 0 3 3 2 0 She9 / Mdm33 family Mce4_CUP1 PF11887.8 ORY95383.1 - 0.021 14.3 0.6 0.033 13.6 0.6 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative GIT1_C PF12205.8 ORY95383.1 - 0.047 13.8 4.1 0.15 12.2 4.1 1.9 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Gp-FAR-1 PF05823.12 ORY95383.1 - 0.1 13.0 5.5 0.17 12.3 4.1 2.2 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2205 PF10224.9 ORY95383.1 - 0.67 10.0 13.7 2.3 8.3 2.1 3.4 2 1 1 3 3 3 0 Short coiled-coil protein LptF_LptG PF03739.14 ORY95383.1 - 0.7 8.7 3.0 1.3 7.8 3.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Vac_Fusion PF02346.16 ORY95383.1 - 1.5 8.5 7.8 1.8 8.3 1.6 3.4 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Fez1 PF06818.15 ORY95383.1 - 1.6 9.1 27.2 0.17 12.3 16.6 2.3 2 0 0 2 2 2 0 Fez1 bZIP_1 PF00170.21 ORY95383.1 - 1.7 8.8 16.3 1.4 9.1 0.8 4.0 1 1 4 5 5 5 0 bZIP transcription factor DUF1664 PF07889.12 ORY95383.1 - 3.4 7.7 10.7 0.37 10.9 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 ORY95383.1 - 4.2 6.5 6.0 10 5.3 6.0 1.7 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 ORY95383.1 - 5 7.8 19.6 1.5 9.5 4.8 4.1 1 1 0 3 3 3 0 SlyX SPAM PF02090.15 ORY95383.1 - 7.1 6.4 18.9 4.7 7.0 4.7 2.6 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein Roughex PF06020.11 ORY95383.1 - 7.7 5.5 12.9 16 4.5 12.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein YabA PF06156.13 ORY95383.1 - 8.1 7.2 18.3 1.6 9.4 5.3 3.7 1 1 3 4 4 4 0 Initiation control protein YabA Zip PF02535.22 ORY95383.1 - 8.3 5.5 6.0 16 4.6 6.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Nramp PF01566.18 ORY95384.1 - 1.7e-104 349.7 19.7 2.2e-56 191.4 5.7 2.4 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein MFS_1 PF07690.16 ORY95385.1 - 4.1e-37 127.9 79.8 1.2e-30 106.7 46.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily C_GCAxxG_C_C PF09719.10 ORY95385.1 - 0.62 10.4 3.7 0.28 11.5 0.5 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Kelch_4 PF13418.6 ORY95386.1 - 5e-18 64.8 0.5 2.9e-05 24.0 0.0 4.7 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY95386.1 - 6.6e-15 54.8 0.1 0.00037 20.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 ORY95386.1 - 2.5e-14 52.9 1.8 0.00032 20.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 ORY95386.1 - 1e-11 44.8 8.4 3e-05 24.2 0.0 5.7 7 0 0 7 7 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY95386.1 - 6.9e-08 32.2 0.0 0.1 12.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif BTB PF00651.31 ORY95386.1 - 1.2e-06 28.8 0.3 3.1e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 ORY95386.1 - 1.4e-05 24.6 0.3 0.13 11.8 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Coilin_N PF15862.5 ORY95386.1 - 0.0021 17.9 5.4 0.0021 17.9 5.4 1.9 2 0 0 2 2 2 1 Coilin N-terminus DUF4746 PF15928.5 ORY95386.1 - 0.0044 16.5 1.8 0.011 15.2 1.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4746) HAUS6_N PF14661.6 ORY95386.1 - 0.052 13.1 13.7 0.097 12.2 13.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Serinc PF03348.15 ORY95386.1 - 0.23 10.3 1.8 0.45 9.4 1.8 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Glyco_transf_41 PF13844.6 ORY95386.1 - 0.26 9.7 6.0 0.4 9.0 6.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 MCU PF04678.13 ORY95386.1 - 0.34 11.0 7.6 0.77 9.8 7.6 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter YjbH PF06082.11 ORY95386.1 - 0.6 8.9 11.7 0.91 8.3 11.7 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH CLN3 PF02487.17 ORY95386.1 - 0.8 8.7 7.2 1.6 7.7 7.2 1.4 1 0 0 1 1 1 0 CLN3 protein Sec62 PF03839.16 ORY95386.1 - 2 7.9 7.7 4.1 6.9 7.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 CPSF100_C PF13299.6 ORY95386.1 - 2.3 8.4 19.4 0.08 13.1 11.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 ORY95386.1 - 3.9 6.4 18.1 6.5 5.7 18.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S49_N PF08496.10 ORY95386.1 - 4.4 7.4 11.3 8.7 6.4 11.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 ORY95386.1 - 4.4 7.0 9.1 0.43 10.3 4.5 1.6 2 0 0 2 2 1 0 Connexin CCDC84 PF14968.6 ORY95386.1 - 4.9 6.7 19.4 7.6 6.0 19.4 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 CSG2 PF16965.5 ORY95386.1 - 6.9 5.5 5.9 12 4.7 5.9 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator GBP_C PF02841.14 ORY95386.1 - 8.2 5.7 23.4 15 4.8 23.4 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Melibiase_2 PF16499.5 ORY95387.1 - 9.4e-13 48.0 0.1 4.7e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 ORY95387.1 - 1.1e-10 41.4 0.0 3.4e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY95387.1 - 0.0025 16.8 0.3 0.011 14.7 0.1 2.1 2 1 0 2 2 2 1 Melibiase Syntaxin PF00804.25 ORY95388.1 - 4.1e-07 29.9 9.3 6.4e-07 29.2 9.3 1.4 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY95388.1 - 2.8e-06 27.2 0.7 2.8e-06 27.2 0.7 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 ORY95388.1 - 9e-05 22.8 7.8 0.021 15.2 3.4 2.7 2 1 1 3 3 3 2 Syntaxin-like protein MCPsignal PF00015.21 ORY95388.1 - 0.47 10.2 10.1 0.11 12.2 1.1 2.8 2 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain THOC7 PF05615.13 ORY95388.1 - 0.63 10.3 12.1 0.041 14.2 1.2 3.1 2 1 0 3 3 3 0 Tho complex subunit 7 Hrs_helical PF12210.8 ORY95388.1 - 0.76 10.3 6.7 1.5 9.4 0.4 3.1 3 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate EF-G-binding_N PF07299.11 ORY95388.1 - 0.85 10.2 5.8 0.82 10.2 1.9 3.0 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal COG5 PF10392.9 ORY95388.1 - 1.2 9.4 9.2 0.84 9.8 2.1 3.0 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 ORY95388.1 - 4.2 7.4 11.4 3.3 7.8 1.3 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_C48 PF02902.19 ORY95390.1 - 2.5e-06 27.5 0.0 6.4e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_M48_N PF16491.5 ORY95391.1 - 5.7e-65 218.6 9.5 5.7e-65 218.6 9.5 2.3 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORY95391.1 - 3.4e-46 157.5 0.0 7.4e-46 156.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 ORY95391.1 - 0.00015 21.1 0.0 0.0016 17.7 0.0 2.4 2 1 0 2 2 2 1 BlaR1 peptidase M56 SprT-like PF10263.9 ORY95391.1 - 0.022 14.6 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 SprT-like family DUF2268 PF10026.9 ORY95391.1 - 0.025 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) CLP_protease PF00574.23 ORY95392.1 - 0.19 11.6 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Clp protease DDE_3 PF13358.6 ORY95394.1 - 0.0014 18.4 0.0 0.0014 18.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 ORY95395.1 - 0.0013 19.3 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Phage_AlpA PF05930.12 ORY95395.1 - 0.0021 17.9 0.0 0.048 13.5 0.0 3.0 4 0 0 4 4 4 1 Prophage CP4-57 regulatory protein (AlpA) HTH_17 PF12728.7 ORY95395.1 - 0.017 15.3 0.0 0.05 13.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 ORY95395.1 - 0.035 13.9 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 ORY95395.1 - 0.038 14.1 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sec3_C PF09763.9 ORY95396.1 - 8.5e-158 526.9 18.5 8.5e-158 526.9 18.5 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 ORY95396.1 - 9.7e-20 70.5 0.2 2.5e-19 69.2 0.2 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 ORY95396.1 - 0.00046 19.1 4.9 0.00046 19.1 4.9 3.1 3 1 0 3 3 3 1 Vps52 / Sac2 family Sec3_C_2 PF15278.6 ORY95396.1 - 0.028 14.7 3.8 0.15 12.5 0.6 3.4 2 1 1 3 3 3 0 Sec3 exocyst complex subunit Auts2 PF15336.6 ORY95396.1 - 0.32 11.1 3.9 0.67 10.0 3.9 1.5 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein NAM-associated PF14303.6 ORY95396.1 - 8.2 7.1 16.9 0.027 15.2 5.3 2.7 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain Xpo1 PF08389.12 ORY95397.1 - 0.0023 18.0 0.2 0.022 14.8 0.0 2.8 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_C PF08767.11 ORY95397.1 - 0.0042 16.3 0.0 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 CRM1 C terminal TPR_1 PF00515.28 ORY95399.1 - 1.4e-50 167.2 33.6 4.2e-08 32.7 0.1 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY95399.1 - 2.8e-45 148.8 28.7 1.2e-05 25.1 0.0 10.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY95399.1 - 3.8e-31 104.7 22.8 5e-05 23.2 2.2 10.5 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 ORY95399.1 - 7.7e-26 88.6 8.6 0.0005 20.7 0.1 8.7 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORY95399.1 - 1.5e-25 89.5 15.3 8e-06 26.3 0.5 6.9 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORY95399.1 - 3.2e-25 86.6 20.2 0.00053 20.2 0.1 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY95399.1 - 1.4e-24 86.4 9.9 4e-05 24.2 0.8 6.7 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY95399.1 - 1.3e-23 83.0 21.4 1.9e-05 24.9 2.5 7.0 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY95399.1 - 2e-20 72.2 34.1 6.4e-06 25.8 1.4 9.3 5 2 4 9 9 9 5 TPR repeat TPR_7 PF13176.6 ORY95399.1 - 5.2e-19 66.8 15.2 0.025 14.6 0.5 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 ORY95399.1 - 8.3e-18 64.3 10.4 0.00023 21.3 0.4 6.9 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 ORY95399.1 - 1.1e-17 63.4 18.0 0.014 16.0 0.0 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY95399.1 - 1.5e-09 38.0 16.5 6.1e-07 29.6 4.3 3.6 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORY95399.1 - 1.1e-07 31.3 8.6 0.0031 16.8 3.4 5.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY95399.1 - 0.0046 16.8 14.8 16 5.5 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY95399.1 - 0.0048 17.2 4.3 1.7 9.0 0.1 5.1 3 2 3 6 6 6 1 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY95399.1 - 0.02 14.6 2.5 19 5.0 0.0 4.2 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 ChAPs PF09295.10 ORY95399.1 - 0.048 12.6 7.3 1.6 7.7 0.7 3.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) ARL6IP6 PF15062.6 ORY95399.1 - 0.1 12.8 0.5 0.37 10.9 0.5 2.0 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix BTAD PF03704.17 ORY95399.1 - 0.26 11.7 9.2 5.5 7.4 0.1 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain SNAP PF14938.6 ORY95399.1 - 0.29 10.5 15.3 22 4.3 0.0 4.4 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP DUF627 PF04781.12 ORY95399.1 - 1.1 9.3 2.9 12 5.9 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_3 PF07720.12 ORY95399.1 - 1.1 9.3 24.8 2.1 8.5 1.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF1751 PF08551.10 ORY95400.1 - 5.8e-26 91.0 2.1 1.5e-25 89.6 2.1 1.8 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 ORY95400.1 - 9.6e-08 32.2 9.9 2.5e-07 30.8 9.9 1.7 1 0 0 1 1 1 1 Rhomboid family Glyco_hydro_20 PF00728.22 ORY95401.1 - 4.8e-94 315.7 0.1 6.3e-94 315.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY95401.1 - 3e-21 76.5 0.0 6.3e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY95401.1 - 2e-07 31.8 0.1 3.5e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RNase_J_C PF17770.1 ORY95401.1 - 0.25 12.4 0.3 0.81 10.8 0.1 2.0 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain PhyH PF05721.13 ORY95402.1 - 3.1e-54 184.5 0.0 3.7e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORY95402.1 - 0.0081 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase F-box-like PF12937.7 ORY95403.1 - 1.4e-05 24.9 0.2 5.7e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY95403.1 - 1.7e-05 24.5 0.9 0.00013 21.8 0.0 2.9 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 ORY95403.1 - 0.12 12.2 4.0 2.6 7.9 0.2 4.2 2 2 1 3 3 3 0 Leucine rich repeat FMO-like PF00743.19 ORY95405.1 - 1.7e-15 56.5 0.1 6e-11 41.5 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY95405.1 - 7.8e-12 45.3 0.0 1.9e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY95405.1 - 3.9e-09 36.2 0.0 0.00059 19.2 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY95405.1 - 4.4e-09 35.9 0.9 0.00018 20.8 0.0 3.2 2 1 1 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY95405.1 - 2e-06 27.6 0.0 0.00046 19.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY95405.1 - 5.3e-06 26.5 0.3 0.053 13.5 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY95405.1 - 0.00013 21.3 5.4 0.0078 15.5 2.4 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY95405.1 - 0.00041 19.5 0.3 0.36 9.9 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ORY95405.1 - 0.00042 19.6 0.0 0.00083 18.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ORY95405.1 - 0.0044 15.8 0.3 0.014 14.1 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORY95405.1 - 0.044 14.4 1.1 0.18 12.4 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY95405.1 - 0.047 12.8 0.1 0.074 12.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 ORY95405.1 - 0.062 12.6 0.0 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ORY95405.1 - 0.11 11.8 0.1 0.27 10.5 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase adh_short_C2 PF13561.6 ORY95406.1 - 2.5e-52 177.8 6.7 4.3e-50 170.5 6.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY95406.1 - 2.5e-47 160.9 4.4 3e-47 160.6 4.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY95406.1 - 2.5e-13 50.3 0.8 4.1e-13 49.7 0.8 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ORY95406.1 - 3.1e-05 24.1 1.4 5.6e-05 23.3 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 ORY95406.1 - 0.0014 18.5 0.4 0.002 18.0 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gly_rich_SFCGS PF14272.6 ORY95406.1 - 0.041 13.9 0.5 0.041 13.9 0.5 2.1 2 1 0 2 2 2 0 Glycine-rich SFCGS ATP-synt_ab_Xtn PF16886.5 ORY95406.1 - 0.099 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension Sec23_trunk PF04811.15 ORY95407.1 - 2.7e-76 256.3 0.0 3.8e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORY95407.1 - 2.3e-30 105.2 0.5 4.4e-30 104.3 0.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORY95407.1 - 5.7e-25 87.1 0.4 1.2e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ORY95407.1 - 1.8e-16 59.9 6.2 3.3e-16 59.0 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY95407.1 - 4.2e-15 55.4 0.0 1.5e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat UL42 PF17638.2 ORY95407.1 - 0.16 11.9 1.2 0.29 11.1 0.3 1.9 2 0 0 2 2 2 0 HCMV UL42 Ribosomal_S7 PF00177.21 ORY95408.1 - 2.2e-33 115.0 1.2 2.8e-33 114.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MAGI_u5 PF16666.5 ORY95408.1 - 0.00019 21.6 0.8 0.00033 20.8 0.8 1.4 1 0 0 1 1 1 1 Unstructured region on MAGI MFS_1 PF07690.16 ORY95409.1 - 1.2e-42 146.2 9.9 1.2e-42 146.2 9.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY95409.1 - 1.3e-12 47.4 0.9 1.3e-12 47.4 0.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter FPN1 PF06963.12 ORY95409.1 - 0.00054 18.6 0.0 0.0014 17.3 0.0 1.7 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF4637 PF15470.6 ORY95409.1 - 0.021 14.6 2.2 0.037 13.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ctr PF04145.15 ORY95409.1 - 0.025 15.2 1.0 0.22 12.1 0.0 2.8 2 1 0 2 2 2 0 Ctr copper transporter family Connexin PF00029.19 ORY95409.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Connexin DUF3040 PF11239.8 ORY95409.1 - 0.11 12.7 0.2 0.11 12.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) R3H PF01424.22 ORY95410.1 - 1.6e-07 31.2 0.0 1.5e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 R3H domain RRM_1 PF00076.22 ORY95410.1 - 0.0011 18.8 0.1 0.0044 16.8 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_4 PF12763.7 ORY95411.1 - 6.6e-35 119.2 0.0 1.9e-18 66.3 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ORY95411.1 - 1.2e-05 25.7 0.0 0.61 10.6 0.1 3.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY95411.1 - 0.00031 20.1 0.0 2 8.2 0.0 4.2 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 ORY95411.1 - 0.0051 16.6 0.1 22 5.3 0.0 4.3 4 0 0 4 4 4 0 EF-hand domain SOGA PF11365.8 ORY95411.1 - 0.012 16.8 8.5 0.012 16.8 8.5 3.5 1 1 2 3 3 3 0 Protein SOGA UBA PF00627.31 ORY95411.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain YchF-GTPase_C PF06071.13 ORY95411.1 - 0.24 11.6 0.9 4.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF933) Cep57_MT_bd PF06657.13 ORY95411.1 - 0.3 11.6 21.6 0.086 13.3 7.7 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Golgin_A5 PF09787.9 ORY95411.1 - 0.64 9.4 28.7 1.3 8.4 28.7 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Laminin_II PF06009.12 ORY95411.1 - 0.71 9.9 20.4 0.039 14.0 6.8 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF812 PF05667.11 ORY95411.1 - 2 7.2 26.1 3.2 6.5 26.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EzrA PF06160.12 ORY95411.1 - 2.7 6.1 21.8 5.5 5.0 21.8 1.5 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sec8_exocyst PF04048.14 ORY95411.1 - 3 7.7 17.2 0.09 12.7 6.6 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Spc7 PF08317.11 ORY95411.1 - 5.1 5.9 35.1 37 3.0 35.2 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 ORY95411.1 - 6.5 6.8 40.8 0.62 10.1 32.8 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 ORY95411.1 - 6.5 5.9 33.5 2 7.5 11.7 2.2 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF2353 PF09789.9 ORY95411.1 - 7.3 5.8 33.5 1.7 8.0 27.2 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) RGS PF00615.19 ORY95412.1 - 4.8e-27 94.6 0.1 9.4e-27 93.6 0.1 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 ORY95412.1 - 6.9e-13 48.4 0.6 1.6e-07 31.3 0.1 3.7 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_A22B PF04258.13 ORY95413.1 - 3.7e-85 285.9 9.1 5e-85 285.5 9.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 ORY95413.1 - 4.4e-06 26.4 4.5 1.2e-05 25.0 4.5 1.7 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease V_ATPase_I PF01496.19 ORY95413.1 - 0.012 13.5 0.8 0.02 12.9 0.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myc_N PF01056.18 ORY95413.1 - 0.22 11.4 10.2 0.03 14.2 6.0 1.5 2 0 0 2 2 2 0 Myc amino-terminal region DUF4746 PF15928.5 ORY95413.1 - 0.51 9.7 16.0 0.018 14.5 9.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 ORY95413.1 - 1.1 8.9 17.2 1.2 8.8 0.0 3.1 2 1 0 2 2 2 0 FAM176 family Connexin PF00029.19 ORY95413.1 - 2 8.1 7.0 4.4 7.0 3.4 2.7 3 0 0 3 3 3 0 Connexin CENP-B_dimeris PF09026.10 ORY95413.1 - 7.4 7.0 0.0 7.4 7.0 0.0 2.9 2 1 1 3 3 3 0 Centromere protein B dimerisation domain Ribosomal_L22 PF00237.19 ORY95414.1 - 2.8e-26 91.7 0.6 4.6e-26 91.1 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e HLH PF00010.26 ORY95415.1 - 4.2e-12 45.8 2.4 9.8e-12 44.7 2.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HSP90 PF00183.18 ORY95415.1 - 0.011 14.7 2.1 0.013 14.4 2.1 1.2 1 0 0 1 1 1 0 Hsp90 protein Myc-LZ PF02344.15 ORY95415.1 - 0.34 11.0 5.3 0.75 10.0 2.3 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain YabA PF06156.13 ORY95415.1 - 1.3 9.7 8.8 0.4 11.3 3.8 2.2 1 1 1 2 2 2 0 Initiation control protein YabA NRBF2 PF08961.10 ORY95415.1 - 4.8 6.7 11.0 0.2 11.2 4.5 2.1 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Thioredoxin PF00085.20 ORY95416.1 - 5.8e-29 100.1 0.2 6.9e-29 99.9 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY95416.1 - 4.1e-08 33.6 0.1 1.6e-07 31.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORY95416.1 - 1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 ORY95416.1 - 1.8e-05 24.5 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY95416.1 - 5.2e-05 23.5 0.0 0.0008 19.7 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 ORY95416.1 - 0.00094 19.1 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 ORY95416.1 - 0.0031 16.9 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Phosducin PF02114.16 ORY95416.1 - 0.0082 15.1 0.0 0.0093 14.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin DUF836 PF05768.14 ORY95416.1 - 0.054 13.9 0.0 0.071 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) UreF PF01730.16 ORY95417.1 - 7.7e-21 75.1 0.0 1.2e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 UreF PMT2_N PF17987.1 ORY95417.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Hat1_N PF10394.9 ORY95418.1 - 3.6e-44 150.8 0.2 6.4e-44 150.0 0.2 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 ORY95418.1 - 0.00032 20.9 0.0 0.0006 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 ORY95418.1 - 0.0065 16.1 0.3 0.01 15.5 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family Fcf2 PF08698.11 ORY95419.1 - 3.1e-36 123.6 0.3 3.1e-36 123.6 0.3 3.1 3 1 0 3 3 3 1 Fcf2 pre-rRNA processing GTP_EFTU PF00009.27 ORY95420.1 - 7.8e-46 156.1 0.0 1.2e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 ORY95420.1 - 6.7e-40 136.5 10.1 1.1e-39 135.7 10.1 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 ORY95420.1 - 4.8e-25 87.7 0.0 9.7e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY95420.1 - 7.9e-23 80.3 0.0 2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY95420.1 - 3.5e-11 43.3 0.0 8.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY95420.1 - 2.9e-06 27.3 0.3 6.4e-06 26.2 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 ORY95420.1 - 4.6e-06 26.6 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.23 ORY95420.1 - 0.0099 16.0 0.5 1 9.4 0.0 2.7 1 1 1 2 2 2 1 Dynamin family Septin PF00735.18 ORY95420.1 - 0.012 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Septin Ras PF00071.22 ORY95420.1 - 0.036 13.7 0.1 0.12 11.9 0.1 1.8 1 1 0 1 1 1 0 Ras family SRPRB PF09439.10 ORY95420.1 - 0.092 12.2 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DIOX_N PF14226.6 ORY95421.1 - 1.1e-24 87.4 0.0 2.1e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY95421.1 - 1.7e-18 66.9 0.0 3.3e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_2 PF07724.14 ORY95422.1 - 4.1e-42 144.2 0.0 6.1e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ORY95422.1 - 6.5e-15 55.7 0.0 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY95422.1 - 7.2e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY95422.1 - 3.2e-06 27.2 0.0 7.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY95422.1 - 6.1e-06 25.8 0.1 0.00062 19.2 0.1 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ORY95422.1 - 2e-05 24.9 0.1 0.0011 19.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORY95422.1 - 0.00022 21.0 0.0 0.043 13.5 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain ABC_tran PF00005.27 ORY95422.1 - 0.00094 19.7 0.0 0.0034 17.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 ORY95422.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY95422.1 - 0.0016 18.2 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 ORY95422.1 - 0.0024 17.4 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 ORY95422.1 - 0.0027 17.5 0.1 0.013 15.2 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 ORY95422.1 - 0.0047 17.1 0.0 0.028 14.5 0.0 2.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 ORY95422.1 - 0.005 17.2 0.1 0.025 15.0 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain MCM PF00493.23 ORY95422.1 - 0.007 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_14 PF13173.6 ORY95422.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY95422.1 - 0.0085 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 ORY95422.1 - 0.014 15.3 0.0 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 ORY95422.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 ORY95422.1 - 0.025 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 ORY95422.1 - 0.032 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 ORY95422.1 - 0.04 13.7 0.1 0.15 11.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ORY95422.1 - 0.046 13.9 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 ORY95422.1 - 0.076 12.8 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 ORY95422.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_8 PF12780.7 ORY95422.1 - 0.11 11.8 0.0 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_29 PF13555.6 ORY95422.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Swi3 PF07962.12 ORY95423.1 - 1e-16 60.7 0.0 1.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 PAC3 PF10178.9 ORY95424.1 - 4.1e-18 65.3 0.0 5.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 F-box-like PF12937.7 ORY95425.1 - 5.1e-07 29.5 0.1 8.3e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY95425.1 - 0.00014 21.7 0.2 0.00029 20.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain FAD_binding_3 PF01494.19 ORY95426.1 - 1e-28 100.6 0.7 4.8e-27 95.1 0.7 2.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY95426.1 - 2.8e-06 26.8 0.1 0.052 12.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY95426.1 - 5.8e-05 23.2 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY95426.1 - 0.00017 22.1 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY95426.1 - 0.00017 20.9 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY95426.1 - 0.001 18.2 0.0 0.057 12.5 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 ORY95426.1 - 0.0013 18.4 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY95426.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ORY95426.1 - 0.042 12.5 0.0 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ORY95426.1 - 0.049 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 ORY95426.1 - 0.07 12.4 0.0 2.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NFRKB_winged PF14465.6 ORY95426.1 - 0.18 12.0 0.0 7.5 6.8 0.0 2.6 2 0 0 2 2 2 0 NFRKB Winged Helix-like FMO-like PF00743.19 ORY95427.1 - 2.8e-13 49.2 0.0 4.9e-10 38.5 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY95427.1 - 2e-09 37.5 0.0 4.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY95427.1 - 1.7e-07 30.7 0.0 0.00092 18.4 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY95427.1 - 4e-06 26.3 0.1 0.00085 18.7 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY95427.1 - 4.3e-06 26.2 0.0 0.0074 15.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY95427.1 - 1.9e-05 24.4 0.0 0.00053 19.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY95427.1 - 0.00041 20.4 0.0 0.49 10.4 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 ORY95427.1 - 0.0097 15.2 0.2 0.022 14.0 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ORY95427.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY95427.1 - 0.19 10.8 0.6 13 4.7 0.7 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 ORY95427.1 - 0.35 9.5 1.9 0.36 9.5 0.9 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyrophosphatase PF00719.19 ORY95428.1 - 3.2e-46 157.1 0.3 4.2e-46 156.7 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase HofP PF10748.9 ORY95428.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA utilization proteins HofP PAP_central PF04928.17 ORY95429.1 - 4.9e-113 376.2 0.0 6.7e-113 375.7 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY95429.1 - 5.3e-39 133.6 0.3 9.6e-39 132.7 0.3 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY95429.1 - 1.4e-08 34.9 0.0 4.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ORY95429.1 - 0.01 15.6 0.2 0.021 14.6 0.2 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain PI-PLC-X PF00388.19 ORY95430.1 - 1.6e-05 24.5 0.0 3.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain zf-CRD PF17979.1 ORY95431.1 - 2.8e-14 53.5 5.3 2.8e-14 53.5 5.3 3.6 1 1 1 2 2 1 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 ORY95431.1 - 2.9e-07 30.2 8.3 2.9e-07 30.2 8.3 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY95431.1 - 6.4e-07 29.1 8.8 6.4e-07 29.1 8.8 4.4 3 2 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY95431.1 - 1.5e-06 27.9 5.5 1.5e-06 27.9 5.5 4.0 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY95431.1 - 7.3e-06 25.9 5.7 7.3e-06 25.9 5.7 3.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY95431.1 - 9.2e-06 25.7 10.7 9.2e-06 25.7 10.7 3.6 5 0 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY95431.1 - 4.9e-05 23.1 3.0 4.9e-05 23.1 3.0 2.9 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 ORY95431.1 - 6.8e-05 23.1 9.2 6.8e-05 23.1 9.2 4.5 5 0 0 5 5 4 1 Ring finger domain zf-RING_5 PF14634.6 ORY95431.1 - 8e-05 22.5 8.2 8e-05 22.5 8.2 3.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-MIZ PF02891.20 ORY95431.1 - 0.0063 16.2 5.8 0.0063 16.2 5.8 2.5 3 0 0 3 3 2 1 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 ORY95431.1 - 0.011 15.6 7.8 0.011 15.6 7.8 4.4 4 1 0 4 4 3 0 Prokaryotic RING finger family 4 TF_Zn_Ribbon PF08271.12 ORY95431.1 - 0.013 15.0 2.2 0.013 15.0 2.2 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding zf-Di19 PF05605.12 ORY95431.1 - 0.037 14.3 3.2 0.037 14.3 3.2 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-CCHH PF10283.9 ORY95431.1 - 0.057 13.4 3.4 0.12 12.4 3.4 1.5 1 0 0 1 1 1 0 PBZ domain zf-UBP_var PF17807.1 ORY95431.1 - 0.14 11.9 3.2 0.33 10.7 3.2 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger PSD3 PF07626.11 ORY95431.1 - 0.17 12.4 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) TackOD1 PF18551.1 ORY95431.1 - 6.9 6.3 17.5 0.54 9.9 1.9 3.2 3 1 0 3 3 3 0 Thaumarchaeal output domain 1 Glyco_transf_15 PF01793.16 ORY95432.1 - 2.4e-113 378.7 10.1 3e-113 378.4 10.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Asp PF00026.23 ORY95433.1 - 7.8e-71 239.1 0.4 9.3e-71 238.8 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY95433.1 - 6.4e-09 36.3 3.4 8.1e-07 29.4 1.7 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY95433.1 - 1.5e-07 31.9 0.1 0.021 15.4 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY95433.1 - 1.1e-06 29.0 0.0 0.025 15.2 0.0 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 ORY95433.1 - 2.6e-05 24.0 0.2 0.00024 20.9 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Cyclin_N PF00134.23 ORY95435.1 - 5.2e-08 32.7 0.1 8e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY95435.1 - 6.6e-08 33.1 0.6 1.4e-05 25.6 0.7 2.3 2 1 0 2 2 2 2 Cyclin ABC2_membrane PF01061.24 ORY95436.1 - 2e-77 259.3 66.0 5.3e-46 156.7 28.3 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY95436.1 - 1.4e-37 129.2 0.1 3e-19 69.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY95436.1 - 1.5e-25 88.9 1.9 1.6e-19 69.6 0.0 4.0 5 1 1 6 6 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY95436.1 - 2.2e-14 53.8 0.0 4.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 ORY95436.1 - 3.2e-05 24.4 0.0 0.034 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY95436.1 - 6.7e-05 22.8 0.0 0.44 10.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY95436.1 - 9.5e-05 22.4 0.2 0.0071 16.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ORY95436.1 - 0.0007 20.2 0.0 0.056 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 ORY95436.1 - 0.0031 16.7 27.0 0.0031 16.7 27.0 3.4 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.6 ORY95436.1 - 0.0055 16.4 1.2 0.022 14.5 0.3 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY95436.1 - 0.007 16.0 0.0 0.033 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY95436.1 - 0.0082 16.4 0.0 1.2 9.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 ORY95436.1 - 0.016 14.5 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 ORY95436.1 - 0.029 14.5 0.3 0.99 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 ORY95436.1 - 0.041 13.6 0.7 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY95436.1 - 0.046 13.3 0.2 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ORY95436.1 - 0.053 13.8 0.1 0.91 9.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY95436.1 - 0.12 12.5 0.2 9.1 6.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 ORY95436.1 - 0.13 12.7 0.0 27 5.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 ORY95436.1 - 0.14 11.9 0.1 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 ORY95436.1 - 0.2 12.1 0.5 0.61 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 ORY95436.1 - 0.62 9.8 9.8 0.4 10.5 0.2 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated ABC2_membrane PF01061.24 ORY95437.1 - 6.6e-80 267.5 63.0 2.6e-42 144.6 20.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY95437.1 - 2e-37 128.8 0.1 4.6e-19 69.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORY95437.1 - 6.1e-27 93.4 12.7 1.8e-19 69.4 0.0 3.8 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY95437.1 - 9.7e-14 51.7 0.2 2.5e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORY95437.1 - 6.7e-11 41.9 41.5 8.4e-06 25.1 16.8 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 ORY95437.1 - 5.7e-07 30.1 0.0 0.0048 17.3 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY95437.1 - 3.5e-05 23.8 0.1 0.0073 16.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 ORY95437.1 - 0.00011 22.1 0.0 0.45 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 ORY95437.1 - 0.00044 19.6 10.3 0.00091 18.6 0.3 2.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 ORY95437.1 - 0.00071 20.1 0.0 0.056 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY95437.1 - 0.0035 17.6 0.0 1.1 9.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 ORY95437.1 - 0.0053 16.5 1.2 0.022 14.5 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 ORY95437.1 - 0.0097 15.5 0.2 1.1 8.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 ORY95437.1 - 0.012 15.2 0.1 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY95437.1 - 0.029 14.1 0.5 2.5 7.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY95437.1 - 0.042 13.1 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 ORY95437.1 - 0.063 13.5 0.2 0.97 9.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY95437.1 - 0.066 13.3 0.2 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY95437.1 - 0.071 13.3 0.0 0.64 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY95437.1 - 0.078 12.7 0.0 7.8 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY95437.1 - 0.13 12.7 0.3 29 5.1 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ORY95437.1 - 1.8 9.0 3.6 0.61 10.5 0.1 2.0 2 0 0 2 2 1 0 AAA domain BAR PF03114.18 ORY95438.1 - 3e-50 171.1 1.5 3.8e-50 170.8 1.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORY95438.1 - 1.9e-07 31.1 0.2 2.8e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 BAR domain of APPL family SH3BP5 PF05276.14 ORY95438.1 - 0.0034 17.2 0.4 0.0074 16.1 0.1 1.5 1 1 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Arfaptin PF06456.13 ORY95438.1 - 0.0041 16.7 3.5 0.05 13.2 3.5 2.3 1 1 0 1 1 1 1 Arfaptin-like domain THP2 PF09432.10 ORY95438.1 - 0.027 14.5 0.2 1.8 8.6 0.0 2.5 2 1 0 2 2 2 0 Tho complex subunit THP2 B12D PF06522.11 ORY95439.1 - 7.7e-18 64.1 0.0 9.3e-18 63.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SRP72 PF08492.12 ORY95441.1 - 2.9e-16 59.6 11.4 2.9e-16 59.6 11.4 3.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_16 PF13432.6 ORY95441.1 - 2e-13 50.7 26.0 0.0091 16.6 0.2 7.6 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY95441.1 - 3.2e-13 50.0 37.4 0.0095 16.4 0.4 7.3 5 2 2 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORY95441.1 - 2e-12 46.8 23.6 0.23 12.4 0.2 8.0 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORY95441.1 - 1.2e-06 28.1 33.9 0.032 14.4 0.1 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 ORY95441.1 - 1.9e-06 28.1 35.6 0.096 13.4 0.1 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY95441.1 - 4.5e-06 26.8 26.6 0.00035 20.8 3.1 5.6 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY95441.1 - 1.4e-05 25.3 32.2 0.00038 20.7 3.4 6.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY95441.1 - 2.3e-05 24.1 19.8 0.38 10.9 0.1 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY95441.1 - 6e-05 22.8 22.0 0.0053 16.6 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ORY95441.1 - 6.3e-05 23.0 7.7 6.3e-05 23.0 7.7 3.4 2 1 1 3 3 3 1 Putative TPR-like repeat TPR_8 PF13181.6 ORY95441.1 - 0.00075 19.5 25.6 0.49 10.7 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat BTAD PF03704.17 ORY95441.1 - 0.0021 18.5 16.8 0.016 15.6 0.5 5.1 4 2 0 4 4 4 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 ORY95441.1 - 0.006 17.1 4.7 5.1 8.0 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 ORY95441.1 - 0.0087 16.0 0.1 0.0087 16.0 0.1 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORY95441.1 - 0.012 15.3 5.0 0.26 10.9 0.1 3.8 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 ORY95441.1 - 0.018 14.5 27.8 0.15 11.4 0.3 4.6 1 1 1 4 4 4 0 MalT-like TPR region PPR PF01535.20 ORY95441.1 - 0.025 14.8 0.0 48 4.5 0.0 4.4 4 0 0 4 4 4 0 PPR repeat TPR_11 PF13414.6 ORY95441.1 - 0.047 13.4 19.6 0.15 11.7 0.2 6.4 7 0 0 7 7 7 0 TPR repeat GAPES1 PF17155.4 ORY95441.1 - 0.061 12.6 0.5 0.11 11.8 0.5 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain TPR_1 PF00515.28 ORY95441.1 - 0.23 11.3 0.0 0.23 11.3 0.0 7.1 7 1 0 8 8 7 0 Tetratricopeptide repeat Alpha_kinase PF02816.18 ORY95441.1 - 0.37 10.9 4.7 7.2 6.7 0.1 3.0 2 2 1 3 3 3 0 Alpha-kinase family TPR_9 PF13371.6 ORY95441.1 - 0.46 10.7 13.6 2.9 8.1 0.1 5.5 6 2 0 6 6 5 0 Tetratricopeptide repeat Cob_adeno_trans PF01923.18 ORY95441.1 - 1.7 8.8 9.7 12 6.0 0.4 3.6 1 1 1 3 3 3 0 Cobalamin adenosyltransferase TPR_17 PF13431.6 ORY95441.1 - 2.4 8.7 0.0 2.4 8.7 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY95441.1 - 5 7.4 7.9 7 7.0 0.2 3.9 3 2 1 4 4 3 0 Vacuolar sorting protein 39 domain 1 Csm2_III-A PF03750.13 ORY95441.1 - 8.8 7.2 11.0 6 7.7 1.0 3.6 2 1 0 3 3 3 0 Csm2 Type III-A alpha-hel2 PF14456.6 ORY95442.1 - 0.038 13.3 0.2 0.069 12.4 0.0 1.5 2 0 0 2 2 2 0 Alpha-helical domain 2 Nup88 PF10168.9 ORY95443.1 - 4.3e-09 34.8 0.8 4.7e-07 28.0 0.0 2.4 2 1 0 2 2 2 2 Nuclear pore component V_ATPase_I PF01496.19 ORY95443.1 - 1.6 6.6 4.3 3 5.7 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3535 PF12054.8 ORY95444.1 - 1e-111 374.3 2.9 1.9e-109 366.8 0.3 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 ORY95444.1 - 5.9e-62 209.4 0.1 1.9e-61 207.7 0.0 1.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY95444.1 - 2.4e-17 63.3 0.0 7.3e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 ORY95444.1 - 4e-14 51.5 15.3 0.21 11.9 0.1 10.8 11 0 0 11 11 11 3 HEAT repeat TAF6_C PF07571.13 ORY95444.1 - 5.8e-05 23.3 0.0 0.88 9.9 0.0 4.9 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 ORY95444.1 - 0.00017 22.1 0.4 5.5 7.7 0.1 4.2 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORY95444.1 - 0.00021 21.7 15.7 0.21 12.1 0.2 8.0 8 0 0 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 ORY95444.1 - 0.00024 21.4 7.1 0.025 15.0 0.2 6.1 5 1 1 6 6 6 1 HEAT repeats ResIII PF04851.15 ORY95444.1 - 0.0006 19.8 0.0 0.002 18.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY95444.1 - 0.094 11.9 0.0 0.47 9.6 0.0 2.1 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase MoCF_biosynth PF00994.24 ORY95445.1 - 2.5e-60 202.3 1.0 1.5e-31 109.0 0.0 2.6 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.17 ORY95445.1 - 1.2e-33 116.2 2.1 2e-33 115.4 2.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 ORY95445.1 - 8.5e-15 54.7 0.0 2.1e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF1180 PF06679.12 ORY95446.1 - 0.16 12.3 12.6 0.26 11.7 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SPX PF03105.19 ORY95446.1 - 0.67 9.8 11.9 0.77 9.6 11.9 1.0 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 ORY95446.1 - 8 5.2 16.6 9.8 4.9 16.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C2H2 PF00096.26 ORY95448.1 - 4.2e-09 36.4 9.1 3.1e-05 24.2 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 ORY95448.1 - 4e-05 23.8 1.2 0.26 11.6 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 ORY95448.1 - 0.00075 20.1 6.9 0.46 11.5 0.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORY95448.1 - 0.0055 17.3 4.5 1.2 9.8 0.1 2.9 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORY95448.1 - 0.0056 17.0 0.9 0.0056 17.0 0.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORY95448.1 - 0.043 14.2 4.6 2.9 8.4 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORY95448.1 - 0.13 11.9 0.6 0.39 10.4 0.6 1.8 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 ORY95448.1 - 0.53 10.3 8.0 0.66 10.0 0.1 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger Acyltransf_C PF16076.5 ORY95448.1 - 1.6 8.9 3.9 14 5.9 0.1 3.1 1 1 1 3 3 3 0 Acyltransferase C-terminus Fungal_trans PF04082.18 ORY95449.1 - 1.3e-22 80.2 0.7 3.7e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY95449.1 - 9.9e-11 41.6 12.1 1.7e-10 40.9 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AF-4 PF05110.13 ORY95451.1 - 0.11 10.6 13.0 0.13 10.3 13.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HisKA PF00512.25 ORY95451.1 - 0.14 12.3 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Myosin_head PF00063.21 ORY95452.1 - 1.7e-239 796.6 0.0 2.1e-239 796.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 ORY95452.1 - 6e-48 163.0 0.6 9.4e-48 162.4 0.6 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 ORY95452.1 - 1e-15 57.1 0.9 2.1e-15 56.1 0.9 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY95452.1 - 4.1e-13 49.0 0.2 1.1e-12 47.6 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY95452.1 - 3.4e-11 42.6 0.1 1.1e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 ORY95452.1 - 0.0034 17.6 0.3 0.0078 16.5 0.3 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_16 PF13191.6 ORY95452.1 - 0.019 15.4 0.0 0.075 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORY95452.1 - 0.022 15.0 0.1 0.15 12.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 ORY95452.1 - 0.032 13.7 0.2 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 ORY95452.1 - 0.17 11.8 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 ORY95452.1 - 0.19 12.2 0.4 1.5 9.3 0.1 2.6 3 0 0 3 3 3 0 ABC transporter Peptidase_M28 PF04389.17 ORY95453.1 - 3.5e-36 124.8 0.0 5.2e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY95453.1 - 0.00051 19.8 0.0 0.0007 19.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PGM_PMM_I PF02878.16 ORY95454.1 - 1.1e-15 57.6 0.1 6.9e-09 35.5 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 ORY95454.1 - 4e-13 49.3 0.4 1.1e-12 47.9 0.4 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 ORY95454.1 - 0.02 15.1 0.2 0.078 13.2 0.2 2.1 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORY95454.1 - 0.065 13.9 2.7 0.77 10.4 0.9 3.5 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4132 PF13569.6 ORY95454.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) DUF5403 PF17395.2 ORY95454.1 - 0.14 12.5 0.3 0.5 10.7 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5403) NCA2 PF08637.10 ORY95455.1 - 4.4e-87 291.9 2.2 7.1e-87 291.2 2.2 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DUF5487 PF17589.2 ORY95456.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5487) Dodecin PF07311.12 ORY95457.1 - 0.094 13.0 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 Dodecin NTP_transferase PF00483.23 ORY95458.1 - 9e-18 64.7 0.0 1.3e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY95458.1 - 5.9e-09 36.5 0.0 7.1e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain Ofd1_CTDD PF10637.9 ORY95459.1 - 1.6e-78 263.6 0.0 4.4e-75 252.3 0.0 2.8 3 1 0 3 3 3 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORY95459.1 - 1.6e-33 115.2 0.0 4.5e-33 113.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORY95459.1 - 2.1e-16 60.6 0.2 1.2e-15 58.2 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily baeRF_family12 PF18856.1 ORY95459.1 - 0.22 12.1 6.5 9.5 6.8 0.4 3.1 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 S4 PF01479.25 ORY95460.1 - 1.8e-13 49.9 0.0 2.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 ORY95460.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 S4 domain Ub-Mut7C PF14451.6 ORY95460.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin Efg1 PF10153.9 ORY95461.1 - 5.6e-27 94.4 12.5 5.6e-27 94.4 12.5 1.6 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Porph_ging PF09697.10 ORY95461.1 - 1.3 9.6 3.6 0.49 11.0 0.6 2.1 2 2 0 2 2 2 0 Protein of unknown function (Porph_ging) CCDC-167 PF15188.6 ORY95461.1 - 3.8 7.9 12.8 9.2 6.7 7.4 3.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin PF02996.17 ORY95462.1 - 4.2e-18 65.4 0.5 5.1e-18 65.1 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Com_YlbF PF06133.11 ORY95462.1 - 0.022 15.3 0.4 0.022 15.3 0.4 1.6 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Nsp1_C PF05064.13 ORY95462.1 - 0.057 13.2 1.7 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region Speriolin_N PF15058.6 ORY95462.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Speriolin N terminus Osw5 PF17062.5 ORY95462.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Outer spore wall 5 Imm32 PF15566.6 ORY95463.1 - 0.019 14.7 0.3 0.035 13.9 0.3 1.4 1 0 0 1 1 1 0 Immunity protein 32 DDE_3 PF13358.6 ORY95463.1 - 0.048 13.4 0.2 0.048 13.4 0.2 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease IATP PF04568.12 ORY95465.1 - 2.4e-08 34.3 0.4 2.9e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NYD-SP28 PF14772.6 ORY95465.1 - 0.0017 18.4 2.6 0.0023 17.9 2.6 1.2 1 0 0 1 1 1 1 Sperm tail Ribosomal_S19e PF01090.19 ORY95465.1 - 0.022 14.4 0.6 0.023 14.4 0.6 1.1 1 0 0 1 1 1 0 Ribosomal protein S19e HMG_box_5 PF14887.6 ORY95465.1 - 0.023 14.6 0.5 0.025 14.5 0.5 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box 5 p450 PF00067.22 ORY95466.1 - 9.3e-52 176.3 0.0 1.2e-51 176.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyrophosphatase PF00719.19 ORY95467.1 - 3.5e-59 199.2 0.3 4.5e-59 198.8 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase SH3_1 PF00018.28 ORY95468.1 - 1.1e-06 28.2 0.1 2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY95468.1 - 0.0001 22.1 0.2 0.00023 20.9 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY95468.1 - 0.00048 19.8 0.0 0.0023 17.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Homeodomain PF00046.29 ORY95470.1 - 1.5e-16 59.9 1.8 1.9e-16 59.6 1.8 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY95470.1 - 0.0021 17.9 0.1 0.0045 16.9 0.0 1.6 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 ORY95470.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain RanGAP1_C PF07834.11 ORY95470.1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 RanGAP1 C-terminal domain YdaS_antitoxin PF15943.5 ORY95470.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Ada3 PF10198.9 ORY95471.1 - 1.6e-31 109.1 4.6 1.6e-31 109.1 4.6 2.3 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Carboxyl_trans PF01039.22 ORY95472.1 - 8.5e-186 618.4 0.4 9.8e-186 618.2 0.4 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ORY95472.1 - 0.0031 17.0 0.2 0.0081 15.7 0.1 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) GATA PF00320.27 ORY95473.1 - 1.6e-15 56.4 3.2 2.8e-15 55.6 3.2 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY95473.1 - 0.23 11.0 5.5 0.17 11.4 1.4 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Stm1_N PF09598.10 ORY95473.1 - 4 8.3 9.6 18 6.2 9.6 2.2 1 0 0 1 1 1 0 Stm1 DUF3552 PF12072.8 ORY95475.1 - 0.0018 17.7 4.5 0.0018 17.7 4.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) OmpH PF03938.14 ORY95475.1 - 0.12 12.7 9.7 0.036 14.4 4.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0449 PF15136.6 ORY95475.1 - 0.49 10.9 7.4 0.21 12.1 0.9 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 LCD1 PF09798.9 ORY95475.1 - 1.6 7.2 6.2 0.27 9.7 0.6 1.9 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF4200 PF13863.6 ORY95475.1 - 2.2 8.7 12.3 0.28 11.6 6.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-CpG_bind_C PF12269.8 ORY95475.1 - 3 7.6 5.6 0.35 10.6 1.3 1.6 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain SWIRM-assoc_1 PF16495.5 ORY95475.1 - 5.6 7.0 9.2 12 5.9 9.2 1.6 1 0 0 1 1 1 0 SWIRM-associated region 1 Scramblase PF03803.15 ORY95476.1 - 3.2e-56 190.1 0.0 4.2e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Scramblase EF-hand_7 PF13499.6 ORY95477.1 - 1.2e-17 64.1 0.6 1.9e-11 44.3 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY95477.1 - 1e-14 52.9 0.7 1.9e-05 23.8 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY95477.1 - 1e-12 46.8 0.7 1.8e-05 24.3 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 ORY95477.1 - 3.7e-08 33.1 0.3 2.5e-07 30.4 0.2 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 ORY95477.1 - 1.6e-05 25.1 0.1 0.018 15.4 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 ORY95477.1 - 4.2e-05 24.4 0.0 6.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORY95477.1 - 5.6e-05 22.5 1.4 0.00073 18.9 0.2 3.1 3 0 0 3 3 3 1 EF hand UPF0154 PF03672.13 ORY95477.1 - 0.085 12.9 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) MotA_activ PF09114.10 ORY95477.1 - 0.14 12.3 0.1 0.56 10.4 0.0 2.0 2 1 1 3 3 3 0 Transcription factor MotA, activation domain Not1 PF04054.15 ORY95478.1 - 4.1e-137 457.0 1.6 1.1e-136 455.6 1.6 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 ORY95478.1 - 1.5e-96 322.1 1.1 3.2e-96 321.0 0.5 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 ORY95478.1 - 2.1e-49 167.3 0.1 2.1e-49 167.3 0.1 2.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 ORY95478.1 - 6.5e-31 107.2 4.5 6.5e-31 107.2 4.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 ORY95478.1 - 1.3e-27 96.8 0.5 1.3e-27 96.8 0.5 2.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF4724 PF15852.5 ORY95478.1 - 0.053 14.0 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) DPBB_1 PF03330.18 ORY95479.1 - 5.6e-07 29.7 0.7 3.3e-06 27.3 0.7 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY95479.1 - 0.094 12.6 0.5 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 Barwin family SAP PF02037.27 ORY95480.1 - 3.3e-06 26.7 2.7 5.2e-06 26.1 2.7 1.3 1 0 0 1 1 1 1 SAP domain Zip PF02535.22 ORY95480.1 - 0.42 9.8 1.7 0.35 10.1 0.2 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter SPRY PF00622.28 ORY95481.1 - 4.8e-20 71.9 0.0 6.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Endosulfine PF04667.17 ORY95482.1 - 2.7e-28 97.9 0.6 3.2e-28 97.7 0.6 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region NPDC1 PF06809.11 ORY95482.1 - 0.011 14.8 0.1 0.012 14.7 0.1 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) ATP-sulfurylase PF01747.17 ORY95483.1 - 1.5e-87 292.5 0.1 2.1e-87 292.1 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 ORY95483.1 - 5.4e-55 185.6 0.0 9e-55 184.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 ORY95483.1 - 8.5e-53 178.3 0.0 1.4e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 ORY95483.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY95483.1 - 0.017 15.6 0.0 0.032 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 ORY95483.1 - 0.071 12.9 0.1 0.32 10.8 0.1 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 ORY95483.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 2-Hacid_dh_C PF02826.19 ORY95485.1 - 2.1e-06 27.2 0.1 0.00046 19.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY95485.1 - 0.0012 18.6 0.0 0.011 15.4 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF4436 PF14494.6 ORY95485.1 - 0.073 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF1690 PF07956.11 ORY95486.1 - 0.66 10.4 7.0 1.1 9.7 7.0 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Neur_chan_memb PF02932.16 ORY95486.1 - 1.1 9.3 5.1 1.7 8.7 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Fib_alpha PF08702.10 ORY95486.1 - 1.5 9.0 8.6 0.43 10.8 1.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 ORY95486.1 - 3.7 8.1 8.2 21 5.7 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cytochrom_B561 PF03188.16 ORY95487.1 - 4.9e-19 68.8 3.9 4.9e-19 68.8 3.9 2.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 ORY95487.1 - 0.017 14.9 1.5 0.017 14.9 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) BAG PF02179.16 ORY95488.1 - 1.1e-15 57.8 0.9 2.1e-15 56.9 0.9 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 ORY95488.1 - 8e-07 28.7 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY95488.1 - 0.001 19.5 0.0 0.0026 18.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF3368 PF11848.8 ORY95488.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Complex1_LYR PF05347.15 ORY95489.1 - 2.9e-14 52.9 1.6 4.2e-14 52.3 1.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY95489.1 - 8e-05 23.3 1.4 0.00011 22.8 1.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Glyco_hydro_31 PF01055.26 ORY95490.1 - 3.1e-143 478.2 8.3 3.1e-143 478.2 8.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY95490.1 - 4.8e-25 87.7 1.8 2.3e-24 85.5 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 ORY95490.1 - 6.3e-06 26.4 0.1 2.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DinB PF05163.12 ORY95491.1 - 1.2e-06 28.6 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 DinB family Pro_isomerase PF00160.21 ORY95492.1 - 1.2e-46 158.9 0.0 1.3e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn-C2H2_12 PF18112.1 ORY95493.1 - 0.00042 20.7 2.7 0.14 12.7 0.2 2.7 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 ORY95493.1 - 0.001 19.3 0.8 0.32 11.3 0.0 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-WRNIP1_ubi PF18279.1 ORY95493.1 - 0.0049 17.4 1.3 0.022 15.4 0.4 2.3 2 0 0 2 2 2 1 Werner helicase-interacting protein 1 ubiquitin-binding domain RNF220 PF15926.5 ORY95493.1 - 0.0085 15.7 0.2 0.0085 15.7 0.2 5.1 5 1 1 6 6 6 2 E3 ubiquitin-protein ligase RNF220 zf_UBZ PF18439.1 ORY95493.1 - 0.011 15.4 2.9 2.4 7.8 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rad50_zn_hook PF04423.14 ORY95493.1 - 0.024 14.5 1.3 0.49 10.3 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 ORY95493.1 - 0.076 12.9 0.6 14 5.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Prok-RING_4 PF14447.6 ORY95493.1 - 0.084 12.7 0.7 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PRP21_like_P PF12230.8 ORY95493.1 - 0.25 11.2 0.0 0.25 11.2 0.0 4.2 3 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Zn-ribbon_8 PF09723.10 ORY95493.1 - 0.43 10.7 1.5 17 5.6 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-CpG_bind_C PF12269.8 ORY95493.1 - 7.4 6.3 9.2 21 4.8 0.2 3.3 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain GCOM2 PF15328.6 ORY95494.1 - 0.0001 22.8 6.4 0.0011 19.4 6.4 2.5 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 zf-CCHC PF00098.23 ORY95495.1 - 1.9e-14 52.9 26.1 0.00018 21.4 1.1 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 ORY95495.1 - 2e-05 24.2 16.6 0.15 11.8 0.6 4.3 4 0 0 4 4 4 3 Zinc knuckle ADD_DNMT3 PF17980.1 ORY95495.1 - 0.045 13.7 0.9 0.045 13.7 0.9 2.4 2 1 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 zf-CCHC_2 PF13696.6 ORY95495.1 - 0.15 11.9 23.5 0.16 11.8 1.1 4.1 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.6 ORY95495.1 - 3.2 7.5 23.3 1.7 8.4 0.3 4.5 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger Rhodanese_C PF12368.8 ORY95495.1 - 7.5 7.0 19.2 27 5.2 10.6 3.4 1 1 1 2 2 2 0 Rhodanase C-terminal Peripla_BP_2 PF01497.18 ORY95496.1 - 0.015 14.9 0.8 0.026 14.1 0.5 1.5 1 1 0 1 1 1 0 Periplasmic binding protein DUF4404 PF14357.6 ORY95496.1 - 0.17 12.5 0.6 0.34 11.6 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) START PF01852.19 ORY95497.1 - 6.9e-19 68.1 0.2 5e-13 48.9 0.1 2.7 2 0 0 2 2 2 2 START domain DUF953 PF06110.11 ORY95497.1 - 0.068 12.8 0.4 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) CDC37_M PF08565.11 ORY95497.1 - 0.22 11.5 0.1 0.57 10.1 0.1 1.6 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain RBP_receptor PF14752.6 ORY95498.1 - 1.4e-26 93.3 20.3 1.4e-26 93.3 20.3 2.7 1 1 1 2 2 2 1 Retinol binding protein receptor UPRTase PF14681.6 ORY95499.1 - 2.9e-67 226.1 0.0 3.4e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY95499.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Peripla_BP_6 PF13458.6 ORY95499.1 - 0.029 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein GTP_CH_N PF12471.8 ORY95500.1 - 9.9e-93 309.3 0.0 1.4e-92 308.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ORY95500.1 - 2.4e-15 56.5 0.0 3.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 ORY95500.1 - 0.13 11.9 0.0 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family SNF2_N PF00176.23 ORY95501.1 - 1.4e-73 247.6 0.0 2.2e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY95501.1 - 5.4e-21 75.0 0.1 8.5e-20 71.2 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORY95501.1 - 1.3e-09 37.8 4.4 2.6e-09 36.8 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 ORY95501.1 - 3e-09 37.1 0.0 7.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 ORY95501.1 - 6.6e-09 36.0 5.4 1.3e-08 35.1 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain HIRAN PF08797.11 ORY95501.1 - 1.2e-08 34.7 0.0 2.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.29 ORY95501.1 - 3.9e-08 33.3 0.0 9.9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 ORY95501.1 - 3.6e-07 29.9 4.4 7.4e-07 28.9 4.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY95501.1 - 4.2e-07 29.8 4.7 8e-07 28.9 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY95501.1 - 1.1e-06 28.4 5.9 2.2e-06 27.4 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY95501.1 - 2.2e-06 27.6 5.6 5.3e-06 26.3 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY95501.1 - 1.9e-05 24.4 7.7 3.8e-05 23.5 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 ORY95501.1 - 0.00063 19.0 0.3 0.00063 19.0 0.3 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_4 PF15227.6 ORY95501.1 - 0.0032 17.6 7.9 0.006 16.7 7.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORY95501.1 - 0.013 15.5 2.4 0.029 14.4 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger UBA_4 PF14555.6 ORY95501.1 - 0.024 14.4 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain HDA2-3 PF11496.8 ORY95501.1 - 0.068 12.3 0.2 2.7 7.1 0.1 2.7 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 ORY95501.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase zf-RING_4 PF14570.6 ORY95501.1 - 0.25 11.2 8.3 0.59 10.0 8.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ResB PF05140.14 ORY95502.1 - 0.01 14.6 0.7 0.024 13.4 0.7 1.6 1 1 1 2 2 2 0 ResB-like family Septin PF00735.18 ORY95503.1 - 4.8e-111 370.5 1.3 7.1e-111 370.0 1.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY95503.1 - 3.2e-08 33.6 0.1 9.6e-08 32.1 0.0 1.9 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY95503.1 - 3.4e-07 30.0 3.3 3.2e-06 26.8 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY95503.1 - 5e-07 29.8 0.6 5e-07 29.8 0.6 2.7 3 0 0 3 3 3 1 RsgA GTPase Ras PF00071.22 ORY95503.1 - 0.00014 21.5 0.4 0.00046 19.8 0.4 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY95503.1 - 0.00025 21.3 0.1 0.0007 19.8 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORY95503.1 - 0.00027 21.2 1.0 0.0014 18.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 ORY95503.1 - 0.00028 20.3 0.1 0.00073 18.9 0.1 1.7 1 0 0 1 1 1 1 AIG1 family DUF3584 PF12128.8 ORY95503.1 - 0.00091 16.9 6.0 0.0015 16.2 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) RNA_helicase PF00910.22 ORY95503.1 - 0.0016 18.8 0.1 0.0071 16.7 0.1 2.1 1 1 1 2 2 2 1 RNA helicase AAA_16 PF13191.6 ORY95503.1 - 0.0022 18.4 0.1 0.0061 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 ORY95503.1 - 0.0035 17.9 0.6 0.026 15.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter IIGP PF05049.13 ORY95503.1 - 0.0056 15.8 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 ORY95503.1 - 0.0066 15.8 0.2 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.12 ORY95503.1 - 0.013 15.0 0.5 0.032 13.7 0.1 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 ORY95503.1 - 0.015 15.1 2.0 2 8.1 0.3 3.0 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 ORY95503.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 ORY95503.1 - 0.03 14.0 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Gtr1_RagA PF04670.12 ORY95503.1 - 0.035 13.5 0.0 0.09 12.1 0.0 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 ORY95503.1 - 0.043 13.5 1.3 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 ORY95503.1 - 0.047 13.5 0.2 8.2 6.2 0.1 2.4 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 ORY95503.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 ORY95503.1 - 0.052 13.1 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 ORY95503.1 - 0.058 13.5 9.6 1.2 9.2 0.1 3.2 2 1 1 3 3 3 0 Dynamin family T2SSE PF00437.20 ORY95503.1 - 0.079 12.0 0.4 0.17 10.9 0.4 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 ORY95503.1 - 0.17 11.7 0.9 12 5.7 0.4 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 ORY95503.1 - 0.22 11.1 0.8 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain FOXP-CC PF16159.5 ORY95503.1 - 1.1 9.9 6.6 0.26 12.0 2.1 2.4 2 1 0 2 2 1 0 FOXP coiled-coil domain APG6_N PF17675.1 ORY95503.1 - 6.2 7.4 15.1 0.36 11.4 8.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF87 PF01935.17 ORY95503.1 - 7.9 6.5 7.2 0.67 10.0 0.2 2.4 2 1 1 3 3 3 0 Helicase HerA, central domain PhoLip_ATPase_C PF16212.5 ORY95504.1 - 3.4e-84 282.5 21.2 3.4e-84 282.5 21.2 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY95504.1 - 7.7e-26 89.6 4.3 2.7e-25 87.9 4.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY95504.1 - 8.2e-14 51.5 0.0 7.9e-13 48.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY95504.1 - 4.2e-11 43.5 0.6 1e-05 26.0 0.2 3.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY95504.1 - 3.2e-05 23.5 0.0 8e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY95504.1 - 0.0018 18.0 0.2 0.0076 16.0 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF423 PF04241.15 ORY95504.1 - 0.02 15.1 1.0 0.063 13.5 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF423) HAD_2 PF13419.6 ORY95504.1 - 0.16 12.0 0.3 0.92 9.6 0.1 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_S19 PF00203.21 ORY95505.1 - 6.1e-33 112.6 0.4 8.1e-33 112.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 ORY95505.1 - 0.0066 16.5 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH Sde2_N_Ubi PF13019.6 ORY95507.1 - 6.9e-34 117.0 0.3 6.9e-34 117.0 0.3 2.2 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain RCC1 PF00415.18 ORY95508.1 - 9.6e-18 64.6 10.4 8.6e-06 26.3 0.0 6.5 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY95508.1 - 8.9e-16 57.2 21.4 0.00015 21.4 0.3 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 ORY95508.1 - 1.1e-06 28.5 0.3 3.3e-06 26.9 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY95508.1 - 0.0059 16.4 0.9 0.019 14.8 0.9 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY95508.1 - 0.0067 16.3 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 F-box Reg_prop PF07494.11 ORY95508.1 - 0.15 12.4 0.2 7.3 7.2 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller DUF2623 PF11115.8 ORY95510.1 - 0.16 12.1 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) Nucleoporin_N PF08801.11 ORY95511.1 - 3.1e-52 177.8 0.0 4.4e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ORY95511.1 - 5e-22 78.4 4.0 7.1e-22 77.9 4.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Endonuclease_5 PF04493.14 ORY95512.1 - 2.1e-63 213.6 0.0 2.4e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V Glyco_tranf_2_3 PF13641.6 ORY95513.1 - 1.5e-19 70.8 3.3 2.6e-14 53.7 0.7 2.5 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 ORY95513.1 - 5.8e-12 45.0 8.4 6.5e-08 31.6 8.6 3.4 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY95513.1 - 3.4e-09 36.9 17.4 3.4e-09 36.9 17.4 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY95513.1 - 6.7e-07 29.3 0.0 0.0059 16.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY95513.1 - 7.1e-07 28.9 0.3 1.6e-06 27.7 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 TetR_C_34 PF17929.1 ORY95514.1 - 0.17 12.0 1.4 2.8 8.0 0.1 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Put_DNA-bind_N PF06971.13 ORY95514.1 - 0.32 11.1 1.1 9.3 6.4 0.1 2.5 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus FAD_binding_3 PF01494.19 ORY95516.1 - 9.1e-22 77.8 1.3 2.7e-10 40.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 ORY95516.1 - 1.7e-07 30.7 0.1 0.00071 18.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY95516.1 - 0.00056 20.1 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY95516.1 - 0.0011 19.5 0.0 0.19 12.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY95516.1 - 0.0031 17.1 0.1 0.0067 16.0 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY95516.1 - 0.0034 16.5 0.1 0.099 11.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORY95516.1 - 0.0049 16.2 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY95516.1 - 0.037 13.1 0.0 0.092 11.8 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain LRR_6 PF13516.6 ORY95517.1 - 4.4e-21 73.1 26.7 0.0049 16.8 0.1 12.3 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 ORY95517.1 - 2.6e-15 56.3 17.3 4e-05 23.9 1.2 8.7 5 2 5 10 10 10 7 Leucine Rich repeats (2 copies) UBX PF00789.20 ORY95517.1 - 3.8e-12 46.2 0.0 1.6e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 UBX domain LRR_8 PF13855.6 ORY95517.1 - 4.5e-11 42.4 17.6 0.00038 20.2 0.3 6.8 5 2 2 7 7 7 4 Leucine rich repeat UBA PF00627.31 ORY95517.1 - 0.0005 19.9 0.0 0.0017 18.2 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain LRR_1 PF00560.33 ORY95517.1 - 0.012 16.1 16.0 6.5 7.7 0.1 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat AAA_11 PF13086.6 ORY95517.1 - 7.2 6.3 19.5 1.8 8.3 13.2 2.2 2 0 0 2 2 2 0 AAA domain CYSTM PF12734.7 ORY95518.1 - 0.00013 22.2 15.2 0.00013 22.2 15.2 2.2 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance MFS_1 PF07690.16 ORY95520.1 - 3.6e-37 128.1 37.3 3.6e-37 128.1 37.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY95520.1 - 1.2e-13 50.7 12.3 1.2e-13 50.7 12.3 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY95520.1 - 7.5e-06 24.6 3.3 1.6e-05 23.6 3.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1206 PF06724.11 ORY95520.1 - 0.52 10.4 12.2 2.1 8.5 2.9 3.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Mannosyl_trans PF05007.13 ORY95521.1 - 3.6e-82 276.1 23.5 3.6e-65 220.4 20.2 2.3 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) PIG-U PF06728.13 ORY95521.1 - 1.5e-10 40.7 21.7 2.2e-10 40.2 21.5 1.3 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Rhodanese PF00581.20 ORY95522.1 - 1.9e-13 50.9 0.0 2.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain G-alpha PF00503.20 ORY95523.1 - 1.3e-112 376.6 1.6 1.4e-112 376.3 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY95523.1 - 2.1e-15 56.6 0.4 3.8e-10 39.5 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY95523.1 - 0.0012 19.1 0.1 0.6 10.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY95523.1 - 0.0024 17.3 1.0 1.7 8.0 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region SMP_C2CD2L PF18696.1 ORY95523.1 - 0.037 13.9 0.3 0.7 9.7 0.1 2.3 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain AAA_29 PF13555.6 ORY95523.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2733 PF10813.8 ORY95524.1 - 0.076 12.8 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) APG6_N PF17675.1 ORY95526.1 - 0.038 14.5 0.1 0.052 14.1 0.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region PilJ PF13675.6 ORY95526.1 - 0.044 13.8 1.6 0.11 12.5 1.4 1.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sec16_C PF12931.7 ORY95527.1 - 5.8e-91 305.3 0.0 8.2e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 ORY95527.1 - 4.1e-21 75.8 0.0 1.2e-20 74.3 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Prefoldin PF02996.17 ORY95528.1 - 7e-27 93.7 2.8 9.9e-27 93.2 2.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.12 ORY95528.1 - 0.025 14.6 5.7 0.18 11.8 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 ORY95528.1 - 0.041 14.5 2.9 0.84 10.3 0.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HisKA_3 PF07730.13 ORY95528.1 - 0.053 14.0 0.1 0.48 11.0 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase betaPIX_CC PF16523.5 ORY95528.1 - 0.058 13.2 3.5 0.078 12.8 1.5 2.0 2 0 0 2 2 2 0 betaPIX coiled coil YlbD_coat PF14071.6 ORY95528.1 - 0.46 10.7 8.8 0.53 10.5 5.5 2.1 2 0 0 2 2 2 0 Putative coat protein Spc7 PF08317.11 ORY95528.1 - 0.59 9.0 9.6 0.43 9.4 0.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Nop14 PF04147.12 ORY95529.1 - 0.0011 17.3 22.1 0.0011 17.3 22.1 2.7 3 1 0 3 3 3 1 Nop14-like family CDC45 PF02724.14 ORY95529.1 - 0.0031 15.9 16.4 0.0031 15.9 16.4 3.4 3 1 0 3 3 3 1 CDC45-like protein Ribosomal_S17_N PF16205.5 ORY95530.1 - 8.4e-30 103.0 1.3 1.9e-29 101.8 1.3 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORY95530.1 - 5.6e-27 93.6 2.0 1.1e-26 92.7 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 NDT80_PhoG PF05224.12 ORY95531.1 - 4.6e-42 144.3 0.0 7.4e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Kinesin PF00225.23 ORY95532.1 - 4.1e-105 351.4 0.0 4.1e-105 351.4 0.0 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORY95532.1 - 2e-24 86.2 0.0 8.3e-24 84.2 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding BLYB PF05289.11 ORY95532.1 - 0.91 9.8 4.6 1.6 8.9 1.6 2.6 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein NatB_MDM20 PF09797.9 ORY95533.1 - 2.9e-99 332.6 10.5 2.9e-99 332.6 10.5 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit BTAD PF03704.17 ORY95533.1 - 0.00061 20.2 0.1 0.00061 20.2 0.1 3.3 5 0 0 5 5 5 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 ORY95533.1 - 0.0012 19.1 3.0 0.21 11.9 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY95533.1 - 0.0018 18.8 12.8 0.0021 18.6 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY95533.1 - 0.0043 17.0 0.0 0.44 10.7 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat VitD-bind_III PF09164.10 ORY95533.1 - 0.06 13.4 0.7 3 7.9 0.1 2.8 2 0 0 2 2 2 0 Vitamin D binding protein, domain III PreAtp-grasp PF18604.1 ORY95533.1 - 0.085 12.5 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Pre ATP-grasp domain PMC2NT PF08066.12 ORY95533.1 - 3.2 8.5 6.6 4.9 7.9 0.1 4.1 4 0 0 4 4 4 0 PMC2NT (NUC016) domain Aa_trans PF01490.18 ORY95534.1 - 1.1e-76 258.2 34.3 1.2e-76 258.0 34.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Hexokinase_2 PF03727.16 ORY95535.1 - 4e-76 255.6 0.0 7.8e-76 254.7 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 ORY95535.1 - 4.8e-52 176.8 0.0 1.1e-51 175.6 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Oxysterol_BP PF01237.18 ORY95536.1 - 5.1e-33 114.4 7.5 8.8e-31 107.1 7.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein VPS9 PF02204.18 ORY95537.1 - 4.3e-33 113.6 0.0 9.5e-33 112.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 ORY95537.1 - 3.2e-18 65.8 0.6 9.8e-18 64.2 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 ORY95537.1 - 5.9e-05 22.7 0.3 0.00014 21.5 0.1 1.8 2 0 0 2 2 2 1 CUE domain RAMP4 PF06624.12 ORY95538.1 - 3.1e-16 59.2 0.0 3.3e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 GILT PF03227.16 ORY95539.1 - 3.1e-16 59.6 1.0 3.8e-16 59.2 0.2 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) HSF_DNA-bind PF00447.17 ORY95540.1 - 5.1e-27 94.3 0.1 5.1e-27 94.3 0.1 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding DUF1892 PF08987.10 ORY95540.1 - 0.69 10.1 3.8 0.7 10.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1892) Spore_III_AF PF09581.10 ORY95540.1 - 1.7 8.7 10.9 3.2 7.8 10.9 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF4175 PF13779.6 ORY95540.1 - 1.8 6.3 22.8 2.3 6.0 22.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3464 PF11947.8 ORY95540.1 - 4.1 7.2 11.2 0.78 9.5 7.3 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DAO PF01266.24 ORY95541.1 - 1.4e-53 182.7 0.0 2e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY95541.1 - 2.9e-05 23.4 0.0 5.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORY95541.1 - 0.00016 21.8 0.1 0.00037 20.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 ORY95541.1 - 0.00085 18.0 0.0 0.023 13.3 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 ORY95541.1 - 0.00095 18.5 0.2 0.0048 16.2 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY95541.1 - 0.014 14.6 0.1 0.1 11.8 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 ORY95541.1 - 0.024 14.9 0.2 0.084 13.1 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 ORY95541.1 - 0.028 13.5 0.2 0.041 13.0 0.2 1.5 1 1 0 1 1 1 0 FAD binding domain UvrC_HhH_N PF08459.11 ORY95541.1 - 0.033 14.1 0.0 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal Lycopene_cycl PF05834.12 ORY95541.1 - 0.053 12.6 0.1 0.093 11.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORY95541.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ORY95541.1 - 0.11 11.3 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 ORY95541.1 - 0.12 11.7 0.1 0.47 9.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY95541.1 - 0.12 12.6 0.8 0.23 11.7 0.2 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 ORY95541.1 - 0.18 12.3 0.1 0.49 10.9 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_4 PF04669.13 ORY95542.1 - 1.5e-19 70.4 2.6 5.3e-10 39.2 0.3 2.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis Elongin_A PF06881.11 ORY95542.1 - 5.5 7.6 7.9 31 5.2 7.6 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Clathrin PF00637.20 ORY95543.1 - 6.5e-25 87.7 3.6 2.3e-24 85.9 0.3 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.32 ORY95543.1 - 0.00035 21.3 0.0 0.0013 19.5 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY95543.1 - 0.0036 17.5 0.0 0.035 14.4 0.0 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY95543.1 - 0.052 12.9 0.0 0.2 11.0 0.0 1.9 3 0 0 3 3 3 0 WD40-like domain TPR_17 PF13431.6 ORY95543.1 - 0.16 12.4 0.5 1.6 9.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY95543.1 - 1.8 8.9 4.0 5.1 7.4 0.1 3.4 3 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 ORY95543.1 - 3.3 8.1 5.5 11 6.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Ras PF00071.22 ORY95544.1 - 1.1e-48 164.9 0.0 1.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY95544.1 - 5.8e-30 104.0 0.1 1.5e-29 102.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY95544.1 - 1.4e-10 40.9 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 ORY95544.1 - 8.9e-05 22.8 0.2 0.00061 20.2 0.2 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 ORY95544.1 - 0.00029 20.3 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY95544.1 - 0.0005 20.1 0.0 0.00086 19.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 ORY95544.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region G-alpha PF00503.20 ORY95544.1 - 0.011 14.9 2.0 1.4 8.0 0.2 2.4 2 1 0 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.27 ORY95544.1 - 0.012 15.1 0.5 0.057 13.0 0.5 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY95544.1 - 0.022 14.7 0.1 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 ORY95544.1 - 0.023 14.1 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ArgoMid PF16487.5 ORY95544.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute AAA_24 PF13479.6 ORY95544.1 - 0.055 13.2 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY95544.1 - 0.069 13.5 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 ORY95544.1 - 0.083 12.9 0.1 0.2 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY95544.1 - 0.1 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 ORY95544.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Na_Pi_cotrans PF02690.15 ORY95545.1 - 0.18 11.9 3.2 0.21 11.7 2.8 1.6 1 1 0 1 1 1 0 Na+/Pi-cotransporter ABC_membrane_2 PF06472.15 ORY95546.1 - 7.6e-90 301.0 0.6 1.1e-89 300.4 0.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY95546.1 - 1.5e-17 64.4 0.0 4.5e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY95546.1 - 0.00026 20.5 0.1 0.29 10.5 0.1 2.7 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY95546.1 - 0.0018 18.9 0.1 0.0058 17.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ORY95546.1 - 0.0029 17.4 0.1 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY95546.1 - 0.012 15.4 0.2 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY95546.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 ORY95546.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4840 PF16128.5 ORY95546.1 - 0.17 11.9 0.5 0.36 10.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) RhoGAP PF00620.27 ORY95547.1 - 2.3e-40 137.9 2.0 4.4e-40 137.0 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ORY95547.1 - 1.5e-05 25.2 0.1 7e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DHC_N1 PF08385.12 ORY95547.1 - 0.03 13.0 2.2 0.054 12.1 2.2 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Fes1 PF08609.10 ORY95547.1 - 1.4 9.9 5.5 1.5 9.8 0.1 3.6 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 SAC3_GANP PF03399.16 ORY95548.1 - 9.6e-27 94.1 8.3 9e-25 87.6 8.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 ORY95548.1 - 8.5e-06 25.8 1.1 2.1e-05 24.5 0.2 2.0 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Bcl-2 PF00452.19 ORY95549.1 - 0.0078 16.9 0.1 0.088 13.5 0.0 2.9 2 1 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family HEAT_2 PF13646.6 ORY95549.1 - 0.029 14.7 2.8 0.27 11.7 0.0 4.0 5 0 0 5 5 5 0 HEAT repeats HEAT PF02985.22 ORY95549.1 - 0.071 13.4 0.8 17 6.0 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat LIM PF00412.22 ORY95550.1 - 8.4e-21 74.0 38.5 2.2e-10 40.6 5.1 4.5 4 1 0 4 4 4 3 LIM domain Zn-ribbon_8 PF09723.10 ORY95550.1 - 0.021 15.0 2.5 0.021 15.0 2.5 7.0 6 2 0 6 6 6 0 Zinc ribbon domain c-SKI_SMAD_bind PF08782.10 ORY95550.1 - 9.4 6.5 15.3 44 4.4 3.0 3.8 2 1 1 3 3 3 0 c-SKI Smad4 binding domain Homeodomain PF00046.29 ORY95552.1 - 1.7e-17 63.0 3.4 2.4e-17 62.5 3.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY95552.1 - 0.031 14.2 0.3 0.073 13.0 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF3485 PF11984.8 ORY95552.1 - 0.045 13.5 0.1 0.053 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Auxin_canalis PF05703.11 ORY95552.1 - 0.12 12.2 1.9 0.14 12.1 1.9 1.1 1 0 0 1 1 1 0 Auxin canalisation NTF2 PF02136.20 ORY95553.1 - 7.9e-29 100.7 0.1 1.3e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ORY95553.1 - 5.5e-09 35.7 0.5 9.6e-09 34.9 0.5 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY95553.1 - 0.017 15.1 0.2 0.038 14.0 0.2 1.5 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 ORY95553.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 ORY95553.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif An_peroxidase PF03098.15 ORY95555.1 - 4.7e-40 137.7 0.2 1.6e-26 93.0 0.8 3.9 1 1 1 2 2 2 2 Animal haem peroxidase DUF765 PF05570.11 ORY95557.1 - 0.031 14.4 0.1 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) Met_synt_B12 PF02965.17 ORY95560.1 - 1.4e-121 405.2 0.2 2.2e-121 404.5 0.2 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 ORY95560.1 - 4.3e-77 259.5 0.0 8.3e-77 258.6 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 ORY95560.1 - 1.1e-56 192.3 0.1 2.6e-56 191.0 0.1 1.7 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding PF02310.19 ORY95560.1 - 2.8e-19 69.3 2.0 6.3e-18 65.0 0.3 2.9 3 0 0 3 3 3 1 B12 binding domain B12-binding_2 PF02607.17 ORY95560.1 - 1e-11 45.1 0.7 7.9e-11 42.2 0.2 2.8 2 1 0 2 2 2 1 B12 binding domain Cyt-b5 PF00173.28 ORY95561.1 - 1.6e-17 63.4 0.0 2.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PPR_2 PF13041.6 ORY95563.1 - 7.1e-32 109.4 5.6 3.8e-14 52.6 0.1 5.9 3 2 2 5 5 5 5 PPR repeat family PPR PF01535.20 ORY95563.1 - 1.7e-21 74.9 12.5 1.6e-07 31.1 0.1 6.7 6 1 0 6 6 6 4 PPR repeat PPR_3 PF13812.6 ORY95563.1 - 1e-19 70.3 0.8 7.8e-09 35.5 0.0 4.1 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY95563.1 - 1.5e-18 66.2 4.7 1.5e-06 27.8 0.0 5.3 5 1 0 5 5 5 3 PPR repeat PPR_long PF17177.4 ORY95563.1 - 4.5e-11 42.5 1.4 4.9e-09 35.9 0.2 3.3 2 2 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORY95563.1 - 0.00084 20.0 0.1 1.2 10.1 0.0 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat Phage_ABA_S PF18066.1 ORY95563.1 - 0.021 15.5 2.2 3.1 8.6 0.2 3.2 3 1 0 3 3 3 0 Phage ABA sandwich domain MRP-S27 PF10037.9 ORY95563.1 - 0.029 13.2 2.2 0.11 11.3 0.1 2.3 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 ABC_membrane_2 PF06472.15 ORY95564.1 - 3e-60 203.9 0.1 3.9e-60 203.5 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY95564.1 - 5.6e-19 69.0 0.0 1.1e-18 68.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY95564.1 - 6e-05 23.0 0.0 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY95564.1 - 0.00056 20.5 0.1 0.0075 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ORY95564.1 - 0.0018 17.8 0.0 0.075 12.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY95564.1 - 0.028 14.2 0.0 0.088 12.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_27 PF13514.6 ORY95564.1 - 0.084 12.5 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ORY95564.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 ORY95564.1 - 0.13 12.2 0.1 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 ORY95564.1 - 0.18 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TMEM208_SND2 PF05620.11 ORY95565.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Rxt3 PF08642.10 ORY95565.1 - 0.025 15.4 0.5 0.059 14.1 0.1 1.8 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 HEAT_2 PF13646.6 ORY95566.1 - 1.5e-12 47.7 0.9 0.00036 20.9 0.1 3.9 2 2 0 3 3 3 3 HEAT repeats HEAT PF02985.22 ORY95566.1 - 6.5e-11 41.5 12.3 0.022 15.0 0.3 6.1 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.6 ORY95566.1 - 5e-09 36.5 12.1 0.033 14.7 0.1 5.6 5 2 1 6 6 6 4 HEAT-like repeat Arm PF00514.23 ORY95566.1 - 0.0059 16.6 6.5 3.3 7.9 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 ORY95566.1 - 0.018 15.1 0.2 0.73 9.9 0.0 3.1 2 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 ORY95566.1 - 0.21 11.3 1.9 13 5.4 0.0 3.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) HEAT_PBS PF03130.16 ORY95566.1 - 0.88 10.4 3.7 80 4.3 0.0 4.2 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat DUF4042 PF13251.6 ORY95567.1 - 2.8e-33 115.1 1.9 7.7e-32 110.5 1.9 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4042) HEAT PF02985.22 ORY95567.1 - 6.3e-09 35.3 9.6 0.0042 17.2 0.1 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 ORY95567.1 - 5.6e-06 26.7 0.3 6.3 7.4 0.0 5.6 4 1 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 ORY95567.1 - 0.00012 22.4 0.1 0.39 11.1 0.0 3.7 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 ORY95567.1 - 0.13 12.3 5.1 2.3 8.2 0.3 3.3 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 F-box-like PF12937.7 ORY95569.1 - 4.1e-06 26.6 0.6 9.1e-06 25.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY95569.1 - 1.2e-05 25.0 0.4 3.1e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain DUF4436 PF14494.6 ORY95570.1 - 4.1e-33 114.7 0.0 5.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4307 PF14155.6 ORY95570.1 - 0.27 11.1 1.2 0.91 9.4 0.0 2.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4307) RasGEF PF00617.19 ORY95571.1 - 5.3e-55 186.3 0.0 1.1e-54 185.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY95571.1 - 5.1e-25 87.7 0.9 5.1e-25 87.7 0.9 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif DC_STAMP PF07782.13 ORY95572.1 - 0.097 12.5 0.7 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein DUF1180 PF06679.12 ORY95572.1 - 0.38 11.1 5.3 5.2 7.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pyridoxal_deC PF00282.19 ORY95573.1 - 5.9e-85 285.2 0.0 7.3e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ORY95573.1 - 9.3e-05 21.8 0.0 0.00016 21.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ORY95573.1 - 0.00012 21.2 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V F-box PF00646.33 ORY95574.1 - 4.4e-11 42.4 0.2 1.5e-10 40.7 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY95574.1 - 1.9e-07 30.8 0.2 5.2e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like Gln-synt_C PF00120.24 ORY95575.1 - 2.7e-22 79.2 0.0 4.8e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ORY95575.1 - 1.2e-13 50.6 0.0 1.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4678 PF15727.5 ORY95576.1 - 0.032 13.5 1.8 0.037 13.3 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) PK PF00224.21 ORY95579.1 - 8.3e-171 567.5 1.0 1e-170 567.2 1.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORY95579.1 - 6.1e-41 139.3 0.0 1.4e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORY95579.1 - 0.01 15.0 0.3 0.033 13.3 0.0 1.8 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 ORY95579.1 - 0.079 12.0 0.1 0.58 9.1 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DAHP_snth_FXD PF18152.1 ORY95579.1 - 0.085 12.7 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain Cellulase PF00150.18 ORY95579.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Cnn_1N PF07989.11 ORY95580.1 - 1.4e-17 63.6 3.5 1.4e-17 63.6 3.5 3.4 3 0 0 3 3 3 1 Centrosomin N-terminal motif 1 RILP PF11461.8 ORY95580.1 - 0.0092 16.2 0.5 0.0092 16.2 0.5 3.2 3 0 0 3 3 3 1 Rab interacting lysosomal protein GcrA PF07750.11 ORY95580.1 - 0.061 13.7 0.4 0.17 12.3 0.4 1.7 1 0 0 1 1 1 0 GcrA cell cycle regulator Tyosinase_C PF18132.1 ORY95580.1 - 0.11 13.2 0.3 0.35 11.6 0.1 1.9 2 0 0 2 2 2 0 Tyosinase C-terminal domain Cep57_CLD_2 PF14197.6 ORY95580.1 - 0.44 10.7 15.3 7.4 6.7 0.3 4.1 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 TSC22 PF01166.18 ORY95580.1 - 4.5 7.7 11.4 8.5 6.8 0.2 4.2 4 1 1 5 5 5 0 TSC-22/dip/bun family HLH PF00010.26 ORY95581.1 - 2e-17 62.9 0.5 2e-17 62.9 0.5 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Spectrin PF00435.21 ORY95581.1 - 0.029 14.9 0.2 0.029 14.9 0.2 3.7 3 1 1 4 4 4 0 Spectrin repeat Trimer_CC PF08954.11 ORY95581.1 - 0.14 11.7 3.6 0.78 9.3 3.6 2.3 1 0 0 1 1 1 0 Trimerisation motif KxDL PF10241.9 ORY95581.1 - 0.31 11.3 12.7 0.3 11.4 0.5 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein TssO PF17561.2 ORY95581.1 - 0.39 10.8 0.1 0.39 10.8 0.1 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO CENP-H PF05837.12 ORY95581.1 - 2.3 8.6 9.4 0.19 12.1 1.5 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 ORY95581.1 - 5.8 6.2 12.1 0.45 9.8 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RhoGAP PF00620.27 ORY95582.1 - 2.6e-39 134.5 1.1 6.3e-39 133.2 1.1 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 ORY95582.1 - 0.0014 18.8 0.8 0.013 15.8 0.0 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain EMC3_TMCO1 PF01956.16 ORY95582.1 - 0.0057 16.4 0.0 0.018 14.8 0.0 1.8 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like PH PF00169.29 ORY95583.1 - 1.5e-19 70.4 0.0 3.8e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY95583.1 - 1.7e-07 31.6 0.1 1.7e-07 31.6 0.1 2.5 3 1 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 ORY95583.1 - 4.5e-05 23.8 0.1 0.00013 22.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 ORY95583.1 - 0.00029 21.0 1.7 0.0029 17.9 1.7 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain CtaG_Cox11 PF04442.14 ORY95584.1 - 2.3e-60 203.0 3.0 2.5e-60 202.9 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF2722 PF10846.8 ORY95584.1 - 0.0062 15.5 3.5 0.0069 15.4 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Consortin_C PF15281.6 ORY95584.1 - 0.013 15.4 0.4 0.031 14.3 0.1 1.7 1 1 1 2 2 2 0 Consortin C-terminus Claudin_2 PF13903.6 ORY95584.1 - 0.17 11.6 0.3 0.27 11.0 0.3 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Big_2 PF02368.18 ORY95584.1 - 0.33 10.9 3.2 0.82 9.6 3.2 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Spt20 PF12090.8 ORY95584.1 - 2.9 7.4 16.5 4.5 6.8 16.5 1.2 1 0 0 1 1 1 0 Spt20 family eIF-5a PF01287.20 ORY95585.1 - 2.2e-28 98.2 0.3 3.3e-28 97.6 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ORY95585.1 - 0.017 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain EMP70 PF02990.16 ORY95586.1 - 3.5e-213 709.0 4.9 4.2e-213 708.7 4.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 ORY95586.1 - 6.6 5.6 44.1 0.018 14.0 16.4 3.0 1 1 2 3 3 3 0 Major Facilitator Superfamily DUF202 PF02656.15 ORY95587.1 - 4.4e-14 52.7 5.8 4.4e-14 52.7 5.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) F-box PF00646.33 ORY95588.1 - 4.6e-05 23.2 3.5 6.3e-05 22.7 1.8 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY95588.1 - 0.0033 17.3 1.3 0.024 14.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY95588.1 - 0.0092 16.4 7.1 30 5.2 0.1 5.8 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY95588.1 - 1.4 9.7 3.6 85 4.3 0.0 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat adh_short PF00106.25 ORY95589.1 - 3.4e-42 144.1 0.1 4.8e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY95589.1 - 3.7e-20 72.5 0.0 5.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY95589.1 - 1.3e-06 28.5 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY95589.1 - 5.5e-05 22.4 0.1 7.7e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORY95589.1 - 0.0081 16.4 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORY95589.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Complex1_51K PF01512.17 ORY95589.1 - 0.06 13.2 0.1 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit cobW PF02492.19 ORY95590.1 - 4.2e-34 117.7 0.0 5.4e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORY95590.1 - 0.00045 20.3 0.0 0.0054 16.8 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 ORY95590.1 - 0.0035 16.3 0.1 1.5 7.7 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 ORY95590.1 - 0.0093 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 ORY95590.1 - 0.012 16.2 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY95590.1 - 0.022 15.1 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 ORY95590.1 - 0.042 13.8 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 ORY95590.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 ORY95590.1 - 0.061 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein TIP49 PF06068.13 ORY95590.1 - 0.079 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 ORY95590.1 - 0.11 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RPAP1_C PF08620.10 ORY95590.1 - 0.64 10.2 4.8 1.2 9.3 4.8 1.5 1 0 0 1 1 1 0 RPAP1-like, C-terminal FHA PF00498.26 ORY95591.1 - 2.4e-10 40.6 0.5 4.1e-10 39.9 0.5 1.4 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 ORY95591.1 - 1.2e-09 38.3 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY95591.1 - 0.0037 17.6 0.0 0.0047 17.2 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Glyco_transf_21 PF13506.6 ORY95592.1 - 3.9e-43 146.9 0.0 5.8e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORY95592.1 - 7.9e-23 81.5 0.0 1.2e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY95592.1 - 2.7e-15 56.8 2.2 4.7e-15 56.0 2.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY95592.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DC_STAMP PF07782.13 ORY95592.1 - 0.19 11.5 1.2 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 DC-STAMP-like protein C2 PF00168.30 ORY95593.1 - 2.2e-23 82.5 0.5 2.7e-23 82.2 0.5 1.1 1 0 0 1 1 1 1 C2 domain NEAT PF05031.12 ORY95593.1 - 0.062 13.9 0.2 0.1 13.2 0.2 1.6 1 1 0 1 1 1 0 Iron Transport-associated domain Ecl1 PF12855.7 ORY95594.1 - 1.1e-07 33.2 19.0 4.1e-07 31.3 19.0 1.8 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 ORY95594.1 - 0.0009 19.3 2.7 0.002 18.1 2.7 1.6 1 0 0 1 1 1 1 MYND finger SR-25 PF10500.9 ORY95594.1 - 1.9 8.0 6.6 2.5 7.7 6.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNase_PH PF01138.21 ORY95595.1 - 3.1e-21 76.3 0.0 5.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY95595.1 - 9e-12 44.9 0.0 2.3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Tex_N PF09371.10 ORY95596.1 - 0.0032 17.2 0.7 0.0055 16.4 0.7 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HAMP PF00672.25 ORY95596.1 - 0.036 14.4 0.0 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 HAMP domain Laminin_II PF06009.12 ORY95596.1 - 0.038 14.0 1.0 0.2 11.6 1.1 2.0 1 1 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 ORY95596.1 - 0.065 12.6 1.9 0.11 11.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 ORY95596.1 - 0.11 11.5 1.9 0.27 10.3 1.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 ORY95596.1 - 0.14 12.3 5.9 0.047 13.8 2.7 1.8 2 0 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.12 ORY95596.1 - 0.23 12.0 2.4 2.3 8.7 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TatC PF00902.18 ORY95596.1 - 0.37 10.6 3.5 1.1 9.0 3.5 1.8 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) OmpH PF03938.14 ORY95596.1 - 0.73 10.2 8.7 4.4 7.6 8.7 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.12 ORY95596.1 - 1.1 9.2 6.6 0.67 9.8 2.1 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF4203 PF13886.6 ORY95597.1 - 4.6e-26 91.7 21.9 1e-25 90.6 21.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2157 PF09925.9 ORY95597.1 - 4 7.2 19.4 1.2e+02 2.4 18.5 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PWWP PF00855.17 ORY95598.1 - 7.2e-19 68.0 0.2 7.2e-19 68.0 0.2 2.7 2 1 1 3 3 3 1 PWWP domain PI3K_1B_p101 PF10486.9 ORY95598.1 - 0.056 11.2 10.3 0.073 10.9 10.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 ORY95598.1 - 0.63 7.1 12.6 0.96 6.5 12.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HSP70 PF00012.20 ORY95601.1 - 4.7e-163 543.6 3.6 4.7e-163 543.6 3.6 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY95601.1 - 4.2e-14 52.1 0.0 9.2e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein 2-Hacid_dh PF00389.30 ORY95601.1 - 0.074 12.7 1.1 0.18 11.4 0.5 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Ketoacyl-synt_C PF02801.22 ORY95601.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Tlr3_TMD PF17968.1 ORY95602.1 - 0.0052 16.9 0.5 0.012 15.8 0.5 1.6 1 0 0 1 1 1 1 Toll-like receptor 3 trans-membrane domain FAD_binding_3 PF01494.19 ORY95603.1 - 1.1e-18 67.7 0.5 6.6e-13 48.6 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY95603.1 - 3.8e-06 26.3 0.1 0.031 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY95603.1 - 2.2e-05 23.9 0.0 0.028 13.7 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY95603.1 - 4e-05 24.1 0.0 0.041 14.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY95603.1 - 7.7e-05 22.9 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY95603.1 - 0.0011 18.2 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY95603.1 - 0.0019 17.3 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY95603.1 - 0.0064 16.1 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY95603.1 - 0.027 13.4 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 ORY95603.1 - 0.029 13.6 0.2 11 5.2 0.0 2.9 3 1 0 3 3 3 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ORY95603.1 - 0.064 12.0 0.0 0.68 8.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 ORY95603.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 ORY95604.1 - 2e-22 79.9 0.1 1.4e-11 44.3 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY95604.1 - 7.5e-05 22.1 0.2 0.18 11.0 0.1 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY95604.1 - 0.0014 19.1 0.0 2 9.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY95604.1 - 0.0084 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY95604.1 - 0.056 12.7 0.0 5.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 ORY95605.1 - 4.4e-30 104.6 0.0 2.7e-29 102.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY95605.1 - 1.4e-18 67.4 0.0 8.7e-18 64.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY95605.1 - 4.7e-05 23.4 0.0 6.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ORY95605.1 - 0.0039 16.5 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ORY95605.1 - 0.0057 16.1 0.0 0.0076 15.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acatn PF13000.7 ORY95607.1 - 1.2e-166 555.5 24.0 2.2e-87 293.8 11.6 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Sulfotransfer_4 PF17784.1 ORY95610.1 - 4.2e-61 206.5 0.0 4.8e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95610.1 - 2.4e-06 28.1 0.1 0.00013 22.4 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 ORY95611.1 - 1e-45 156.2 0.1 1.1e-45 156.1 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95611.1 - 9.8e-05 22.8 0.1 0.00016 22.1 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase family RRM_1 PF00076.22 ORY95612.1 - 1.4e-27 95.3 0.0 2.7e-09 36.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY95612.1 - 6.3e-09 35.6 0.0 0.039 13.8 0.0 3.7 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY95612.1 - 2.7e-07 30.2 0.0 0.00043 19.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY95612.1 - 0.00018 21.6 0.0 0.14 12.3 0.0 4.4 5 0 0 5 5 5 1 RNA recognition motif RRM_3 PF08777.11 ORY95612.1 - 0.00072 19.6 0.2 0.71 9.9 0.1 2.5 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 ORY95612.1 - 0.0034 17.3 0.0 1.2 9.1 0.0 3.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 ORY95612.1 - 0.0052 16.6 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) SUIM_assoc PF16619.5 ORY95612.1 - 0.0063 16.5 10.1 0.53 10.4 0.8 2.5 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 SET_assoc PF11767.8 ORY95612.1 - 0.1 12.2 0.1 2 8.1 0.0 2.6 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Zn_clus PF00172.18 ORY95613.1 - 8.4e-08 32.2 7.1 1.5e-07 31.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.22 ORY95613.1 - 0.27 10.4 10.9 0.6 9.3 10.9 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 ORY95613.1 - 0.53 9.7 7.7 0.84 9.0 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PIEZO PF15917.5 ORY95613.1 - 1.1 8.7 15.2 2.4 7.6 15.2 1.6 1 0 0 1 1 1 0 Piezo ALMT PF11744.8 ORY95613.1 - 3.9 6.2 13.7 7.1 5.3 13.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter MAJIN PF15077.6 ORY95613.1 - 4 7.1 14.7 8.3 6.1 14.7 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein Ras PF00071.22 ORY95614.1 - 1.9e-58 196.6 0.2 2.3e-58 196.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY95614.1 - 7.3e-35 119.8 0.1 1.3e-34 118.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY95614.1 - 2.7e-16 59.5 0.0 3.5e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY95614.1 - 1e-09 38.1 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY95614.1 - 9.9e-07 28.5 0.2 1.3e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY95614.1 - 1.5e-06 28.3 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY95614.1 - 0.00049 20.1 1.4 0.18 11.7 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY95614.1 - 0.0055 17.1 0.0 0.0084 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 ORY95614.1 - 0.2 10.8 0.1 5.5 6.0 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit PBP PF01161.20 ORY95615.1 - 4.4e-21 75.6 0.0 5.5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Myb_DNA-binding PF00249.31 ORY95616.1 - 1.6e-14 53.8 0.3 3.2e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2 PF00096.26 ORY95616.1 - 1.7e-13 50.2 17.9 0.00012 22.3 0.7 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY95616.1 - 3.9e-11 42.8 16.6 1.1e-05 25.7 1.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain Myb_DNA-bind_6 PF13921.6 ORY95616.1 - 1.8e-10 40.9 0.1 5.9e-10 39.3 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_6 PF13912.6 ORY95616.1 - 3.2e-07 30.2 14.5 0.00072 19.5 1.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY95616.1 - 0.00087 19.9 15.6 0.014 16.2 2.0 4.4 4 0 0 4 4 3 3 C2H2-type zinc finger SLIDE PF09111.10 ORY95616.1 - 0.002 18.2 0.0 0.002 18.2 0.0 2.2 3 0 0 3 3 3 1 SLIDE zf-C2H2_aberr PF17017.5 ORY95616.1 - 0.0031 17.7 0.1 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 Aberrant zinc-finger TFIIA PF03153.13 ORY95616.1 - 0.0043 17.1 39.7 0.0043 17.1 39.7 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_7 PF15963.5 ORY95616.1 - 0.012 15.5 0.7 0.012 15.5 0.7 2.7 2 0 0 2 2 2 0 Myb DNA-binding like Rap1_C PF11626.8 ORY95616.1 - 0.014 15.4 0.2 0.014 15.4 0.2 2.6 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SUIM_assoc PF16619.5 ORY95616.1 - 0.017 15.2 2.9 0.017 15.2 2.9 4.2 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 C1_4 PF07975.12 ORY95616.1 - 2.3 8.5 7.4 10 6.5 6.9 2.5 1 1 0 1 1 1 0 TFIIH C1-like domain HLH PF00010.26 ORY95617.1 - 3.6e-13 49.2 0.3 1.1e-12 47.7 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain hNIFK_binding PF12196.8 ORY95617.1 - 0.06 12.8 2.8 0.17 11.4 2.8 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK CTP_transf_3 PF02348.19 ORY95617.1 - 0.61 10.0 5.4 0.26 11.2 2.3 1.9 2 0 0 2 2 2 0 Cytidylyltransferase DDHD PF02862.17 ORY95618.1 - 4.6e-30 105.5 0.5 1.5e-29 103.8 0.5 1.8 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.7 ORY95618.1 - 0.044 14.4 0.2 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cas_Csy2 PF09614.10 ORY95618.1 - 0.047 13.0 2.0 0.074 12.4 2.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Abhydrolase_1 PF00561.20 ORY95618.1 - 0.19 11.4 0.7 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4667 PF15700.5 ORY95618.1 - 0.38 10.8 7.6 0.62 10.1 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF4770 PF15994.5 ORY95618.1 - 1.4 9.2 7.5 2.7 8.2 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Peptidase_S15 PF02129.18 ORY95618.1 - 1.8 8.1 0.0 1.8 8.1 0.0 2.5 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) XAP5 PF04921.14 ORY95618.1 - 1.8 8.4 10.8 3.1 7.5 10.8 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator GREB1 PF15782.5 ORY95618.1 - 4.3 4.3 8.9 5.7 3.9 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 ORY95618.1 - 6.1 5.0 14.1 8.7 4.5 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 ORY95619.1 - 2.2e-31 109.2 0.0 3.9e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kelch_5 PF13854.6 ORY95619.1 - 3.9e-19 68.2 8.9 2.2e-05 24.3 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 ORY95619.1 - 3.3e-17 61.8 11.4 0.0033 17.0 0.4 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 ORY95619.1 - 5.1e-15 55.2 13.4 8.7e-06 25.7 0.1 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY95619.1 - 1.3e-13 50.9 28.6 1.5e-07 31.6 0.1 7.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY95619.1 - 3.4e-12 46.2 13.7 0.00047 20.3 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 ORY95619.1 - 3e-10 39.6 9.9 0.0035 17.3 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Pkinase_Tyr PF07714.17 ORY95619.1 - 1e-07 31.6 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY95619.1 - 0.00082 18.8 0.0 0.0022 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like EphA2_TM PF14575.6 ORY95619.1 - 0.0026 18.6 0.0 0.0092 16.8 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 ORY95619.1 - 0.057 13.6 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FBPase PF00316.20 ORY95620.1 - 7.5e-75 250.6 0.1 1.1e-74 250.1 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Caleosin PF05042.13 ORY95621.1 - 3.6e-37 127.9 0.6 5.9e-37 127.2 0.6 1.3 1 0 0 1 1 1 1 Caleosin related protein GTSE1_N PF15259.6 ORY95621.1 - 4.2 7.5 5.8 32 4.7 0.1 3.7 4 0 0 4 4 4 0 G-2 and S-phase expressed 1 PBP1_TM PF14812.6 ORY95622.1 - 0.027 14.8 10.6 0.25 11.8 1.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bd3614-deam PF14439.6 ORY95622.1 - 0.027 14.5 0.2 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase FAM176 PF14851.6 ORY95622.1 - 0.072 12.8 12.1 0.17 11.6 0.2 2.4 2 1 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 ORY95622.1 - 0.076 13.4 13.1 0.11 12.9 0.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TMEM51 PF15345.6 ORY95622.1 - 0.38 10.6 7.1 0.075 12.9 2.9 1.8 1 1 0 2 2 2 0 Transmembrane protein 51 DUF4695 PF15766.5 ORY95622.1 - 0.6 10.4 5.8 0.52 10.6 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) E7 PF00527.18 ORY95622.1 - 1.2 9.3 4.2 7.9 6.8 1.7 2.4 2 0 0 2 2 2 0 E7 protein, Early protein PI3K_1B_p101 PF10486.9 ORY95622.1 - 6.8 4.3 13.6 1 7.1 9.9 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Methyltransf_31 PF13847.6 ORY95623.1 - 2.1e-15 56.8 0.0 4.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY95623.1 - 1.4e-14 54.0 0.0 3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY95623.1 - 9.6e-14 51.9 0.1 4.7e-13 49.7 0.1 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY95623.1 - 8.1e-09 36.0 0.1 5.8e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 ORY95623.1 - 2.1e-08 34.1 0.0 4.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 ORY95623.1 - 1.3e-07 32.3 0.0 3.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY95623.1 - 3.6e-06 26.6 0.4 6.9e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 ORY95623.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 ORY95623.1 - 0.00016 21.6 0.0 0.00034 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY95623.1 - 0.00024 21.1 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 ORY95623.1 - 0.00052 19.7 0.0 0.00094 18.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_10 PF05971.12 ORY95623.1 - 0.0015 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA methyltransferase CMAS PF02353.20 ORY95623.1 - 0.0024 17.2 0.0 0.0074 15.6 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 ORY95623.1 - 0.0037 16.6 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PseudoU_synth_2 PF00849.22 ORY95623.1 - 0.0066 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase N6_Mtase PF02384.16 ORY95623.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase PCMT PF01135.19 ORY95623.1 - 0.025 14.3 0.0 0.083 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) S4_2 PF13275.6 ORY95623.1 - 0.039 13.8 0.3 0.089 12.6 0.3 1.6 1 0 0 1 1 1 0 S4 domain Methyltransf_4 PF02390.17 ORY95623.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Eco57I PF07669.11 ORY95623.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Eco57I restriction-modification methylase WAC_Acf1_DNA_bd PF10537.9 ORY95624.1 - 2.1e-31 108.4 0.3 2.1e-31 108.4 0.3 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 ORY95624.1 - 9.3e-19 67.7 0.0 9.3e-19 67.7 0.0 4.1 2 2 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 ORY95624.1 - 3.5e-14 52.8 0.6 6e-14 52.1 0.6 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 ORY95624.1 - 1.9e-06 27.2 0.1 4.1e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Utp14 PF04615.13 ORY95624.1 - 0.0076 14.9 29.3 0.014 14.0 29.3 1.4 1 0 0 1 1 1 1 Utp14 protein DUF3439 PF11921.8 ORY95624.1 - 0.97 9.4 11.0 1.9 8.5 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AJAP1_PANP_C PF15298.6 ORY95624.1 - 4.1 7.6 16.2 11 6.2 16.2 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DAGK_cat PF00781.24 ORY95625.1 - 1.4e-13 50.6 0.0 2.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 ORY95625.1 - 2.8e-13 50.5 0.0 4.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain PEPCK_ATP PF01293.20 ORY95626.1 - 1.2e-219 729.7 0.0 1.4e-219 729.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 ORY95626.1 - 0.21 12.0 0.0 0.44 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain zf-RING_2 PF13639.6 ORY95627.1 - 6.1e-13 48.9 8.1 9.4e-13 48.3 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY95627.1 - 5.3e-10 38.9 4.7 1.1e-09 37.8 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY95627.1 - 3.9e-09 36.2 7.1 6.1e-09 35.6 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY95627.1 - 5.1e-07 29.9 5.1 1.1e-06 28.8 5.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY95627.1 - 9.7e-07 28.6 6.6 1.5e-06 27.9 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY95627.1 - 0.00036 20.5 2.9 0.00036 20.5 2.9 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY95627.1 - 0.00053 19.8 8.4 0.00081 19.2 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY95627.1 - 0.00065 19.6 6.6 0.00096 19.1 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY95627.1 - 0.062 13.2 10.6 0.1 12.5 10.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORY95627.1 - 0.28 11.3 4.8 0.69 10.0 4.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 ORY95627.1 - 0.85 9.8 5.9 1.7 8.9 5.9 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY95627.1 - 7.1 6.5 8.8 12 5.8 8.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Seipin PF06775.14 ORY95628.1 - 3.7e-54 183.8 2.9 5.3e-54 183.3 2.9 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Phage_Gp23 PF10669.9 ORY95628.1 - 0.014 15.7 1.7 0.014 15.7 1.7 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4834 PF16118.5 ORY95628.1 - 0.068 14.1 0.2 0.068 14.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) T_cell_tran_alt PF15128.6 ORY95628.1 - 0.28 11.0 3.5 1.2 9.0 0.5 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Sigma_reg_N PF13800.6 ORY95628.1 - 0.46 10.8 3.6 14 6.0 0.2 3.1 2 1 1 3 3 3 0 Sigma factor regulator N-terminal LMBR1 PF04791.16 ORY95628.1 - 2.5 6.9 8.6 1.7 7.4 1.5 2.3 2 1 0 2 2 2 0 LMBR1-like membrane protein CYSTM PF12734.7 ORY95629.1 - 0.087 13.2 74.9 1.8e+04 -8.6 74.9 3.9 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 ORY95629.1 - 0.77 10.4 14.8 0.82 10.3 14.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 ORY95629.1 - 1.6 8.7 18.5 2.4 8.2 18.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RACo_C_ter PF14574.6 ORY95635.1 - 0.046 12.8 0.3 7.2 5.6 0.0 2.2 1 1 1 2 2 2 0 C-terminal domain of RACo the ASKHA domain Sulfotransfer_4 PF17784.1 ORY95638.1 - 3e-32 112.2 0.0 3.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 ORY95639.1 - 1.5e-57 194.9 0.0 1.8e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95639.1 - 0.0015 19.0 0.1 0.015 15.7 0.1 2.5 1 1 1 2 2 2 1 Sulfotransferase family Exonuc_VIII PF06630.11 ORY95639.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII DUF1257 PF06868.11 ORY95639.1 - 0.2 11.9 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Sulfotransfer_4 PF17784.1 ORY95640.1 - 1.7e-56 191.4 0.0 2e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95640.1 - 0.00016 22.1 0.0 0.0063 16.9 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 ORY95641.1 - 2.1e-52 178.1 0.0 2.5e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95641.1 - 3.3e-06 27.7 0.1 0.00029 21.3 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Exonuc_VIII PF06630.11 ORY95641.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Sulfotransfer_4 PF17784.1 ORY95642.1 - 9.6e-43 146.5 0.5 1e-42 146.4 0.5 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95642.1 - 3e-05 24.5 0.9 6.5e-05 23.4 0.9 1.8 1 1 0 1 1 1 1 Sulfotransferase family TnpV PF14198.6 ORY95642.1 - 0.079 13.0 0.1 2 8.5 0.1 2.3 1 1 1 2 2 2 0 Transposon-encoded protein TnpV TRIC PF05197.13 ORY95643.1 - 1.4e-07 31.3 0.2 1.9e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 TRIC channel bZIP_2 PF07716.15 ORY95644.1 - 3.1e-11 43.2 13.0 5.3e-11 42.4 13.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 ORY95644.1 - 6.5e-05 23.1 1.5 0.00011 22.3 1.5 1.3 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_1 PF00170.21 ORY95644.1 - 0.00014 21.9 9.6 0.00024 21.1 9.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF1465 PF07323.12 ORY95644.1 - 0.033 14.0 4.0 0.048 13.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF5094 PF17015.5 ORY95644.1 - 0.16 12.1 2.2 0.23 11.6 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Ytp1 PF10355.9 ORY95645.1 - 4.4e-102 341.0 11.0 4.4e-102 341.0 11.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORY95645.1 - 1.3e-25 89.2 5.3 1.3e-25 89.2 5.3 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Tetraspanin PF00335.20 ORY95645.1 - 0.044 13.5 0.3 0.044 13.5 0.3 3.0 2 1 0 2 2 2 0 Tetraspanin family Cytochrom_B561 PF03188.16 ORY95645.1 - 2.5 8.2 36.4 0.15 12.2 3.0 4.5 5 1 0 5 5 5 0 Eukaryotic cytochrome b561 NHR2 PF08788.11 ORY95646.1 - 0.067 13.0 0.9 0.14 12.0 0.9 1.5 1 0 0 1 1 1 0 NHR2 domain like AT_hook PF02178.19 ORY95647.1 - 0.17 11.8 6.3 0.9 9.6 6.3 2.4 1 0 0 1 1 1 0 AT hook motif peroxidase PF00141.23 ORY95648.1 - 1.3e-42 146.1 0.0 2.4e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Choline_kinase PF01633.20 ORY95649.1 - 1.1e-55 188.5 0.1 9.8e-54 182.2 0.0 2.9 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORY95649.1 - 1.9e-16 60.7 0.1 3.4e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PX PF00787.24 ORY95650.1 - 1.7e-07 31.2 1.1 4.1e-07 30.0 0.6 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY95650.1 - 9.5e-06 25.3 1.2 4.9e-05 23.0 1.2 2.0 1 1 0 1 1 1 1 Vps5 C terminal like Sec2p PF06428.11 ORY95651.1 - 3.3e-14 52.6 9.8 3.3e-14 52.6 9.8 2.4 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Csm1_N PF18504.1 ORY95651.1 - 1.8e-05 25.0 7.7 0.021 15.1 1.7 2.4 2 0 0 2 2 2 2 Csm1 N-terminal domain CEP63 PF17045.5 ORY95651.1 - 0.027 14.4 14.0 0.037 13.9 14.0 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa GAS PF13851.6 ORY95651.1 - 0.039 13.3 14.0 0.056 12.8 14.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 ORY95651.1 - 0.17 11.3 14.7 2.6 7.4 14.7 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 ORY95651.1 - 0.19 11.1 8.8 0.35 10.2 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sas6_CC PF18594.1 ORY95651.1 - 0.22 11.3 0.6 0.6 9.9 0.6 1.7 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Glutaredoxin2_C PF04399.13 ORY95651.1 - 0.46 10.3 5.6 0.23 11.3 2.4 2.0 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain V_ATPase_I PF01496.19 ORY95651.1 - 0.54 8.1 6.6 0.68 7.8 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_porin PF12795.7 ORY95651.1 - 0.55 9.7 18.0 9.4 5.7 18.0 2.1 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Cob_adeno_trans PF01923.18 ORY95651.1 - 0.59 10.2 5.0 1.4 9.0 5.0 1.6 1 1 0 1 1 1 0 Cobalamin adenosyltransferase ABC_tran_CTD PF16326.5 ORY95651.1 - 0.66 10.3 11.9 4 7.7 5.2 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 ORY95651.1 - 0.74 9.3 12.4 0.12 12.0 6.9 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit SlyX PF04102.12 ORY95651.1 - 1.4 9.6 14.1 2.9 8.6 1.8 3.1 1 1 1 2 2 2 0 SlyX DUF4763 PF15960.5 ORY95651.1 - 1.7 7.9 13.7 4.1 6.6 13.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) CC2-LZ PF16516.5 ORY95651.1 - 1.7 9.1 11.5 0.45 10.9 2.5 2.4 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FbpA PF05833.11 ORY95651.1 - 2.2 6.9 12.5 0.066 12.0 3.7 2.0 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Spc7 PF08317.11 ORY95651.1 - 2.2 7.1 13.7 3.7 6.4 13.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 ORY95651.1 - 2.3 8.4 8.4 1.4 9.0 1.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PRKG1_interact PF15898.5 ORY95651.1 - 3.7 8.5 13.8 3 8.8 3.7 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 ORY95651.1 - 6.8 6.0 10.4 0.76 9.1 2.8 2.3 1 1 1 2 2 2 0 FAM76 protein Atx10homo_assoc PF09759.9 ORY95652.1 - 2.8e-35 120.3 1.5 3.5e-35 120.0 0.2 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 ORY95652.1 - 0.00023 21.1 0.0 0.14 12.2 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY95652.1 - 0.038 14.4 0.0 0.48 10.8 0.0 2.6 1 1 1 2 2 2 0 HEAT repeats HEAT PF02985.22 ORY95652.1 - 0.094 13.0 0.1 0.8 10.1 0.0 2.7 3 0 0 3 3 3 0 HEAT repeat RL10P_insert PF17777.1 ORY95652.1 - 0.13 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P AMP-binding PF00501.28 ORY95653.1 - 1.7e-101 339.9 0.0 2.1e-101 339.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY95653.1 - 1.5e-05 25.9 0.0 5.9e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 ORY95654.1 - 3.5e-05 23.6 0.1 8.3e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY95654.1 - 0.00061 19.7 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MBR1 PF17058.5 ORY95654.1 - 0.052 13.8 1.9 5.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 PVL_ORF50 PF07768.11 ORY95654.1 - 0.1 12.9 1.8 0.9 9.9 0.1 2.2 2 0 0 2 2 2 0 PVL ORF-50-like family Neur_chan_memb PF02932.16 ORY95654.1 - 4.8 7.2 5.2 6.9 6.6 5.2 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region KH_1 PF00013.29 ORY95655.1 - 4.4e-55 183.4 6.2 6.5e-19 67.5 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY95655.1 - 2.3e-14 52.9 1.1 0.0032 17.3 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY95655.1 - 6.2e-10 38.8 1.3 0.0016 18.3 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY95655.1 - 0.0013 18.8 0.5 12 6.1 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Ribonuclease_3 PF00636.26 ORY95656.1 - 1e-42 145.0 0.0 3.7e-21 75.7 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 ORY95656.1 - 1.2e-24 86.2 2.6 1e-23 83.3 0.1 3.3 4 0 0 4 4 4 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 ORY95656.1 - 3.8e-22 78.8 0.0 3e-12 46.8 0.0 3.6 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 ORY95656.1 - 1.7e-18 67.0 0.0 4.1e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 ORY95656.1 - 1.8e-12 47.2 0.4 3.7e-12 46.2 0.4 1.5 1 0 0 1 1 1 1 PAZ domain DEAD PF00270.29 ORY95656.1 - 1.1e-11 44.8 0.0 2.5e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY95656.1 - 1.1e-11 45.0 0.0 3.1e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.26 ORY95656.1 - 0.25 12.1 0.6 45 4.9 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF3750 PF12570.8 ORY95657.1 - 0.17 12.6 7.0 15 6.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3750) Pro_isomerase PF00160.21 ORY95658.1 - 2.5e-52 177.3 0.0 6e-52 176.1 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 ORY95658.1 - 3.9e-06 26.9 0.0 2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 ORY95658.1 - 5.4e-06 26.5 0.0 7.7e-05 22.8 0.0 2.5 1 1 1 2 2 2 1 U-box domain Rtf2 PF04641.12 ORY95658.1 - 0.0001 21.8 7.8 0.00011 21.6 3.7 2.8 2 1 0 2 2 2 1 Rtf2 RING-finger DUF4432 PF14486.6 ORY95659.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) CBFB_NFYA PF02045.15 ORY95662.1 - 7.7e-29 100.1 7.3 1.9e-28 98.9 7.3 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ArAE_2 PF10334.9 ORY95663.1 - 4.3e-17 62.7 0.9 1.5e-16 60.9 0.4 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY95663.1 - 3.9e-15 56.1 13.2 3.9e-15 56.1 13.2 2.6 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORY95663.1 - 4e-11 42.2 2.3 4e-11 42.2 2.3 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein family ALMT PF11744.8 ORY95663.1 - 2.8e-07 29.8 0.8 6.3e-07 28.6 0.8 1.6 1 0 0 1 1 1 1 Aluminium activated malate transporter YtxH PF12732.7 ORY95663.1 - 1.3 9.6 0.0 1.3 9.6 0.0 2.7 2 1 0 2 2 2 0 YtxH-like protein FUSC_2 PF13515.6 ORY95665.1 - 2.8e-18 66.3 37.0 3.8e-14 52.9 17.8 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY95665.1 - 1.4e-17 64.4 0.4 2.5e-17 63.5 0.4 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORY95665.1 - 2.8e-13 49.7 21.5 2.9e-07 29.9 3.5 4.3 3 1 1 4 4 4 3 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ORY95665.1 - 5.1e-13 48.7 0.7 5.1e-13 48.7 0.7 2.5 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.12 ORY95665.1 - 2.2e-07 29.8 13.2 2.2e-07 29.8 13.2 2.9 2 2 0 2 2 2 1 Fusaric acid resistance protein family CPP1-like PF11833.8 ORY95665.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 2.5 2 0 0 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like YtxH PF12732.7 ORY95665.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.8 4 0 0 4 4 4 0 YtxH-like protein Melibiase_2 PF16499.5 ORY95666.1 - 5.9e-16 58.5 2.2 4e-08 32.8 0.2 2.1 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 ORY95666.1 - 9.4e-13 48.0 0.0 9.6e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY95666.1 - 0.024 13.6 0.4 0.2 10.6 0.0 2.3 2 1 0 2 2 2 0 Melibiase PMT PF02366.18 ORY95667.1 - 7.5e-70 235.3 14.5 7.5e-70 235.3 14.5 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY95667.1 - 1.9e-58 197.4 5.1 1.9e-58 197.4 5.1 3.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY95667.1 - 1e-09 38.5 3.9 1.4e-08 34.8 3.9 2.1 1 1 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.11 ORY95667.1 - 0.0073 15.5 0.2 0.085 12.0 0.1 2.3 1 1 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor OPT PF03169.15 ORY95668.1 - 1.4e-79 268.4 44.8 1.6e-79 268.2 44.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CTV_P6 PF06706.11 ORY95668.1 - 0.43 10.3 0.1 0.43 10.3 0.1 3.1 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein BORCS8 PF10167.9 ORY95669.1 - 1.4e-16 60.4 0.0 1.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 HAGH_C PF16123.5 ORY95670.1 - 5.7e-23 81.2 0.0 8.2e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORY95670.1 - 1.8e-10 41.2 4.9 1e-08 35.4 4.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY95670.1 - 8.5e-05 22.2 0.3 0.0013 18.3 0.3 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain AhpC-TSA PF00578.21 ORY95671.1 - 4.9e-41 139.5 0.0 6.2e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY95671.1 - 2.6e-17 62.9 0.0 3.4e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY95671.1 - 9.7e-11 41.3 0.0 2.3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin KTI12 PF08433.10 ORY95672.1 - 2.3e-91 306.0 0.0 2.6e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 ORY95672.1 - 7.6e-08 32.6 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Bac_export_3 PF01313.19 ORY95673.1 - 0.071 13.0 0.2 0.071 13.0 0.2 3.2 4 0 0 4 4 4 0 Bacterial export proteins, family 3 DUF202 PF02656.15 ORY95673.1 - 0.55 10.7 16.5 6.2 7.3 5.4 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Oxysterol_BP PF01237.18 ORY95674.1 - 6.5e-86 288.5 0.8 8.1e-84 281.6 0.8 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_S7 PF00177.21 ORY95675.1 - 3.5e-37 127.3 1.0 4.5e-37 127.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e His_Phos_2 PF00328.22 ORY95676.1 - 3.3e-86 290.0 0.0 4.2e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 ORY95676.1 - 3.2e-37 126.6 0.0 1.1e-36 124.9 0.0 2.0 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 ORY95676.1 - 6.8e-06 25.8 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF3446 PF11928.8 ORY95676.1 - 0.073 13.4 0.2 0.25 11.7 0.1 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain ArgJ PF01960.18 ORY95677.1 - 1.7e-149 497.7 2.5 1.9e-149 497.5 2.5 1.0 1 0 0 1 1 1 1 ArgJ family ATP-grasp PF02222.22 ORY95677.1 - 0.037 13.6 0.1 0.23 11.0 0.1 2.0 1 1 0 1 1 1 0 ATP-grasp domain DnaB_2 PF07261.11 ORY95677.1 - 0.087 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Replication initiation and membrane attachment DNA_pol_B PF00136.21 ORY95678.1 - 6.7e-148 493.2 0.3 1.1e-147 492.4 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY95678.1 - 2.9e-82 276.5 0.0 2.2e-80 270.3 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY95678.1 - 2.5e-15 56.7 6.5 4.5e-15 55.9 6.5 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ORY95678.1 - 0.00022 20.2 1.0 0.00053 19.0 0.1 2.0 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 ORY95678.1 - 0.0058 16.6 0.2 0.036 14.1 0.2 2.3 1 1 0 1 1 1 1 RNase_H superfamily zf-RING-like PF08746.11 ORY95678.1 - 0.35 11.2 2.3 1.1 9.7 2.3 1.8 1 0 0 1 1 1 0 RING-like domain TFIIS_C PF01096.18 ORY95678.1 - 0.41 10.5 4.0 1.4 8.8 4.0 1.9 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-ACC PF17848.1 ORY95678.1 - 0.57 10.3 2.5 1 9.5 0.8 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain C1_1 PF00130.22 ORY95678.1 - 1.9 8.5 6.4 0.39 10.6 2.7 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUI1 PF01253.22 ORY95679.1 - 6.9e-19 68.2 0.0 1.5e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 ORY95679.1 - 5.7e-13 49.4 0.3 3.5e-12 46.8 0.1 2.4 2 0 0 2 2 2 1 Pre-PUA-like domain SWIB PF02201.18 ORY95679.1 - 0.001 18.9 0.1 0.0026 17.6 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain PUA PF01472.20 ORY95679.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 PUA domain TRAPP PF04051.16 ORY95680.1 - 2.8e-42 143.9 0.0 3.2e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 ORY95681.1 - 4.3e-09 36.9 10.1 0.0017 19.2 0.6 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat YpjP PF14005.6 ORY95682.1 - 0.052 13.6 0.6 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 YpjP-like protein Spore_GerAC PF05504.11 ORY95682.1 - 0.18 12.0 2.0 0.24 11.6 1.0 1.7 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal EF-G-binding_N PF07299.11 ORY95682.1 - 1.9 9.1 5.2 4 8.0 2.9 2.6 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal FHA PF00498.26 ORY95684.1 - 3.9e-14 52.7 0.1 8.3e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY95684.1 - 6.6e-11 41.8 6.1 6.6e-11 41.8 6.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY95684.1 - 1.5e-08 34.8 7.2 2.9e-08 33.9 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY95684.1 - 3.6e-05 23.5 8.4 6.6e-05 22.7 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY95684.1 - 5e-05 23.5 3.8 0.00019 21.6 3.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY95684.1 - 0.00014 21.6 7.5 0.0003 20.6 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY95684.1 - 0.0002 21.3 7.2 0.00047 20.1 7.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY95684.1 - 0.00071 19.4 4.6 0.0013 18.6 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY95684.1 - 0.07 13.2 10.4 0.16 12.0 10.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.8 ORY95684.1 - 0.14 12.0 1.2 0.3 10.9 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 ORY95684.1 - 0.18 11.7 4.4 0.41 10.6 4.4 1.7 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 ORY95684.1 - 0.79 9.8 8.5 0.046 13.8 1.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HD PF01966.22 ORY95685.1 - 2.6e-05 24.4 1.0 4.7e-05 23.6 1.0 1.4 1 0 0 1 1 1 1 HD domain RmlD_sub_bind PF04321.17 ORY95686.1 - 3.5e-66 223.2 0.0 4.2e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ORY95686.1 - 4e-31 108.3 0.0 5.3e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY95686.1 - 1.5e-15 57.5 0.2 4.8e-15 55.8 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY95686.1 - 2.5e-07 30.1 0.7 1.2e-05 24.6 0.4 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY95686.1 - 9.6e-06 24.9 0.1 0.0015 17.8 0.0 2.8 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ORY95686.1 - 2.8e-05 24.1 0.2 5.5e-05 23.1 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY95686.1 - 0.00023 20.3 0.0 0.00049 19.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ORY95686.1 - 0.00067 19.2 0.8 0.0017 17.8 0.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 ORY95686.1 - 0.0013 18.8 0.7 0.0038 17.3 0.3 2.0 2 2 1 3 3 3 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 ORY95686.1 - 0.0014 18.6 2.2 0.13 12.1 1.6 2.9 2 1 0 2 2 2 1 KR domain NmrA PF05368.13 ORY95686.1 - 0.017 14.7 0.2 0.028 14.0 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short_C2 PF13561.6 ORY95686.1 - 0.024 14.2 0.2 0.072 12.6 0.1 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase HTH_36 PF13730.6 ORY95686.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TEA PF01285.18 ORY95687.1 - 7.7e-31 106.0 0.0 1.9e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain YBD PF17725.1 ORY95687.1 - 0.00025 21.0 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 YAP binding domain Glycos_transf_1 PF00534.20 ORY95688.1 - 8.3e-20 71.0 0.0 2.2e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY95688.1 - 1e-12 48.6 0.0 1.9e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORY95688.1 - 3e-07 30.7 0.0 8.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Helicase_Sgs1 PF11408.8 ORY95688.1 - 0.12 12.4 0.4 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 Sgs1 RecQ helicase Methyltransf_25 PF13649.6 ORY95689.1 - 3.9e-19 69.2 0.0 9.2e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY95689.1 - 8e-17 61.7 0.0 2.3e-16 60.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY95689.1 - 1.7e-16 60.5 0.2 4.2e-16 59.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY95689.1 - 1.7e-13 50.6 0.0 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORY95689.1 - 5.4e-09 36.7 0.0 2.3e-08 34.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY95689.1 - 3.8e-07 29.7 0.0 9.7e-07 28.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY95689.1 - 0.00011 21.7 1.3 0.025 14.0 0.0 3.0 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_2 PF00891.18 ORY95689.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 ORY95689.1 - 0.0043 15.7 0.3 0.0082 14.7 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 ORY95689.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 ORY95689.1 - 0.015 14.8 0.0 0.037 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 ORY95689.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Hypothetical methyltransferase ATP-synt_F PF01990.17 ORY95690.1 - 1.3e-34 118.4 0.1 1.5e-34 118.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 ORY95690.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 PIN like domain RmuC PF02646.16 ORY95690.1 - 0.11 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 RmuC family Bap31 PF05529.12 ORY95691.1 - 1.7e-45 154.2 1.0 3e-45 153.4 1.0 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 ORY95691.1 - 1.3e-12 47.5 9.9 1.3e-12 47.5 9.9 2.2 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 ORY95691.1 - 0.00075 19.7 3.7 0.00075 19.7 3.7 3.1 2 1 1 3 3 3 1 Homeobox associated leucine zipper Phage_GP20 PF06810.11 ORY95691.1 - 0.0033 17.2 10.5 0.0033 17.2 10.5 2.3 1 1 1 2 2 2 1 Phage minor structural protein GP20 Tup_N PF08581.10 ORY95691.1 - 0.012 15.9 3.9 0.012 15.9 3.9 2.3 2 0 0 2 2 2 0 Tup N-terminal Sec34 PF04136.15 ORY95691.1 - 0.013 15.4 6.9 0.02 14.8 6.9 1.3 1 0 0 1 1 1 0 Sec34-like family DUF3498 PF12004.8 ORY95691.1 - 0.018 14.3 7.2 0.02 14.1 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DUF3450 PF11932.8 ORY95691.1 - 0.092 12.0 9.2 0.12 11.7 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF648 PF04890.13 ORY95691.1 - 0.13 12.0 3.8 0.16 11.7 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) FlxA PF14282.6 ORY95691.1 - 0.16 12.0 11.0 0.27 11.3 11.0 1.3 1 0 0 1 1 1 0 FlxA-like protein Fmp27_WPPW PF10359.9 ORY95691.1 - 0.24 10.2 9.9 0.3 9.9 9.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RRP36 PF06102.12 ORY95691.1 - 0.35 10.8 12.3 0.57 10.1 12.3 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 FapA PF03961.13 ORY95691.1 - 0.5 8.9 6.3 0.6 8.7 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SlyX PF04102.12 ORY95691.1 - 1.4 9.6 8.7 0.42 11.3 2.1 2.7 1 1 2 3 3 3 0 SlyX APG6_N PF17675.1 ORY95691.1 - 2.6 8.6 19.2 5 7.6 19.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 ORY95691.1 - 3.3 8.0 12.5 9.5 6.5 12.5 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.6 ORY95691.1 - 4.2 7.5 9.7 9.4 6.3 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) WD40_alt PF14077.6 ORY95691.1 - 4.7 7.1 7.7 1.6 8.6 0.7 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif TMPIT PF07851.13 ORY95691.1 - 4.9 6.3 10.5 5 6.3 9.8 1.4 1 1 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 ORY95691.1 - 7.1 6.5 20.5 0.19 11.6 5.4 3.4 2 1 1 3 3 3 0 Septum formation initiator zf-CSL PF05207.13 ORY95692.1 - 7.6e-24 83.2 1.8 1.3e-23 82.5 1.8 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 ORY95692.1 - 0.079 12.8 2.3 0.14 12.0 2.3 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Malic_M PF03949.15 ORY95693.1 - 3.7e-86 288.6 0.1 4.9e-86 288.2 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORY95693.1 - 5.4e-59 199.0 0.0 9e-59 198.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_3_C PF01915.22 ORY95694.1 - 2.8e-61 207.0 0.0 5e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY95694.1 - 4.9e-52 177.3 0.0 8.1e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY95694.1 - 3e-21 75.3 0.0 5.8e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain RabGAP-TBC PF00566.18 ORY95695.1 - 4.6e-38 131.0 0.5 4.6e-38 131.0 0.5 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Dicty_REP PF05086.12 ORY95695.1 - 2.6 5.9 8.0 4.2 5.2 8.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glutaredoxin PF00462.24 ORY95696.1 - 1.3e-18 67.0 0.0 1.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Velvet PF11754.8 ORY95697.1 - 8.6e-60 202.8 9.0 3.9e-37 128.6 0.1 3.2 2 1 1 3 3 3 3 Velvet factor Enkurin PF13864.6 ORY95698.1 - 0.0013 19.1 1.6 0.0013 19.1 1.6 4.5 1 1 2 3 3 2 1 Calmodulin-binding Macoilin PF09726.9 ORY95698.1 - 0.0091 14.6 35.8 0.028 13.0 35.8 1.9 1 1 0 1 1 1 1 Macoilin family Acyl-CoA_dh_2 PF08028.11 ORY95698.1 - 0.048 13.9 2.1 0.14 12.5 2.1 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain KxDL PF10241.9 ORY95698.1 - 0.55 10.6 22.6 0.069 13.4 4.4 4.1 1 1 1 3 3 3 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 ORY95698.1 - 0.88 9.7 42.5 1.4 9.1 31.6 3.9 3 1 0 3 3 3 0 Tropomyosin like CENP-F_leu_zip PF10473.9 ORY95698.1 - 1.8 8.6 40.7 0.15 12.1 17.7 3.6 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 ORY95698.1 - 2.1 7.9 43.0 25 4.3 0.2 2.9 1 1 0 2 2 2 0 Intermediate filament protein SSP160 PF06933.11 ORY95698.1 - 2.4 6.2 9.3 3.5 5.7 9.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UPF0242 PF06785.11 ORY95698.1 - 6.5 6.8 42.9 6.1 6.9 18.6 3.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 ORY95698.1 - 6.7 6.1 41.1 1.1 8.7 32.3 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 FUSC PF04632.12 ORY95698.1 - 6.8 5.1 12.2 14 4.1 12.0 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 ORY95698.1 - 7.2 6.8 44.7 2.5 8.3 20.5 3.9 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 SMC_N PF02463.19 ORY95700.1 - 1.8e-07 30.8 2.6 3.9e-07 29.7 2.6 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain CENP-F_leu_zip PF10473.9 ORY95700.1 - 0.0055 16.7 1.4 0.0055 16.7 1.4 2.8 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 ORY95700.1 - 0.006 15.5 1.3 0.006 15.5 1.3 2.7 2 1 0 2 2 2 1 Spc7 kinetochore protein DUF3987 PF13148.6 ORY95700.1 - 0.0074 15.3 0.9 0.0074 15.3 0.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Fib_alpha PF08702.10 ORY95700.1 - 0.025 14.8 8.6 0.03 14.5 0.3 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SMC_hinge PF06470.13 ORY95700.1 - 0.1 12.9 0.0 0.81 10.0 0.0 2.6 2 1 0 2 2 2 0 SMC proteins Flexible Hinge Domain GPAT_N PF14829.6 ORY95700.1 - 0.11 12.6 0.0 1.5 8.9 0.0 2.8 2 1 1 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal BLOC1_2 PF10046.9 ORY95700.1 - 0.25 11.7 11.1 0.2 12.0 0.3 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 ORY95700.1 - 0.89 10.0 6.7 1.6 9.2 0.2 4.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper T4SS PF07996.11 ORY95700.1 - 1.1 9.7 9.7 0.048 14.1 1.9 2.4 1 1 1 2 2 2 0 Type IV secretion system proteins Spectrin PF00435.21 ORY95700.1 - 4.7 7.7 12.3 1.7 9.2 3.1 3.4 2 2 1 3 3 3 0 Spectrin repeat AAA_23 PF13476.6 ORY95701.1 - 6.1e-18 66.1 0.2 6.6e-18 65.9 0.2 1.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORY95701.1 - 1.2e-10 41.2 0.1 1.4e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY95701.1 - 9.3e-09 35.5 0.2 9.9e-09 35.4 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY95701.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY95701.1 - 0.00019 21.4 0.2 0.00019 21.4 0.2 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ORY95701.1 - 0.0033 17.8 0.2 0.0042 17.5 0.2 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY95701.1 - 0.0037 17.8 0.7 0.0049 17.4 0.7 1.5 1 1 0 1 1 1 1 ABC transporter AAA_27 PF13514.6 ORY95701.1 - 0.0038 16.8 0.1 0.0047 16.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY95701.1 - 0.0047 16.5 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 ORY95701.1 - 0.034 13.6 0.4 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 ORY95701.1 - 0.045 13.5 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_13 PF13166.6 ORY95701.1 - 0.046 12.4 0.4 0.075 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY95701.1 - 0.073 13.0 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 ORY95701.1 - 0.094 12.2 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 ORY95701.1 - 0.096 12.4 0.1 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY95701.1 - 0.17 12.2 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Med21 PF11221.8 ORY95702.1 - 1e-17 64.8 0.4 1.5e-17 64.2 0.4 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Mitoc_mL59 PF18126.1 ORY95702.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Aa_trans PF01490.18 ORY95703.1 - 3.2e-60 204.0 24.6 4.1e-60 203.6 24.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM237 PF15383.6 ORY95703.1 - 0.02 14.0 0.7 0.053 12.6 0.7 1.6 1 0 0 1 1 1 0 Transmembrane protein 237 DUF727 PF05303.12 ORY95704.1 - 8.9e-08 32.1 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) ACOX PF01756.19 ORY95705.1 - 3.9e-52 176.4 0.4 8.8e-52 175.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORY95705.1 - 1.2e-24 87.3 2.5 1.2e-24 87.3 2.5 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORY95705.1 - 5.6e-13 48.9 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORY95705.1 - 7.5e-06 26.2 1.3 0.00017 21.9 0.0 3.2 4 0 0 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2483 PF10656.9 ORY95705.1 - 0.14 12.4 0.3 0.57 10.4 0.1 2.1 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2483) CCDC154 PF15450.6 ORY95706.1 - 0.0013 17.4 1.1 0.0013 17.4 1.1 1.4 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 154 Cohesin_HEAT PF12765.7 ORY95706.1 - 0.018 15.3 1.4 0.28 11.5 0.1 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion KxDL PF10241.9 ORY95706.1 - 0.024 14.9 5.4 0.024 14.9 5.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein ATP-gua_Ptrans PF00217.19 ORY95706.1 - 0.06 12.8 0.4 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Myb_DNA-bind_3 PF12776.7 ORY95706.1 - 0.16 13.0 1.4 0.44 11.6 0.4 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain GAS PF13851.6 ORY95706.1 - 0.24 10.8 8.3 0.069 12.5 3.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 ORY95706.1 - 1.4 9.1 11.3 0.21 11.8 6.7 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SH3_1 PF00018.28 ORY95707.1 - 2.4e-30 103.9 0.0 3.9e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY95707.1 - 3.7e-19 68.3 0.1 2.6e-10 40.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 ORY95707.1 - 1.8e-11 44.0 0.0 3.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 ORY95707.1 - 2.1e-11 43.4 0.0 1.9e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 ORY95707.1 - 7.4e-07 29.0 0.3 1.4e-06 28.1 0.3 1.4 1 0 0 1 1 1 1 PB1 domain DUF2270 PF10028.9 ORY95709.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) NAD_Gly3P_dh_C PF07479.14 ORY95710.1 - 1.5e-49 168.0 0.2 2.6e-49 167.2 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 ORY95710.1 - 8e-48 162.4 0.1 1.9e-47 161.1 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Baculo_p74 PF04583.12 ORY95710.1 - 0.085 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region CDP-OH_P_transf PF01066.21 ORY95711.1 - 9.2e-19 68.0 0.1 9.2e-19 68.0 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Rpn3_C PF08375.11 ORY95712.1 - 2.5e-29 101.5 0.6 2.5e-29 101.5 0.6 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 ORY95712.1 - 8.4e-21 74.5 0.1 4.5e-20 72.1 0.1 2.3 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 ORY95712.1 - 0.0063 16.5 4.6 0.34 11.1 1.9 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1992 PF09350.10 ORY95713.1 - 5.9e-23 80.8 0.5 1.6e-22 79.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) APC_u14 PF16635.5 ORY95713.1 - 0.027 15.0 2.2 0.027 15.0 2.2 1.9 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr DUF3807 PF12720.7 ORY95713.1 - 0.44 10.8 9.5 0.72 10.1 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Vps39_2 PF10367.9 ORY95714.1 - 3.2e-35 120.9 2.8 1.3e-34 119.0 0.1 3.2 3 0 0 3 3 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 ORY95714.1 - 1.3e-34 120.1 0.0 2.3e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 ORY95714.1 - 1.6e-30 105.6 0.1 1.6e-30 105.6 0.1 4.0 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 ORY95714.1 - 5e-17 62.1 18.9 6.8e-12 45.5 3.3 3.7 4 0 0 4 4 4 3 Region in Clathrin and VPS TPR_7 PF13176.6 ORY95714.1 - 0.00035 20.4 2.3 3.2 8.0 0.0 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY95714.1 - 0.0013 18.5 6.4 1 9.3 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY95714.1 - 0.0016 18.4 4.6 0.76 10.0 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY95714.1 - 0.002 18.6 0.2 0.002 18.6 0.2 3.3 4 1 1 5 5 4 1 Tetratricopeptide repeat PPR PF01535.20 ORY95714.1 - 0.009 16.2 0.0 3.5 8.1 0.0 4.0 4 0 0 4 4 4 1 PPR repeat ANAPC3 PF12895.7 ORY95714.1 - 0.024 14.8 2.9 0.079 13.2 0.2 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY95714.1 - 0.025 14.9 5.9 0.27 11.5 0.5 3.7 3 2 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY95714.1 - 0.11 13.2 0.5 5.6 7.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY95714.1 - 0.13 12.2 0.9 12 5.9 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat FerA PF08165.11 ORY95714.1 - 0.13 12.2 1.2 0.3 11.1 0.5 2.0 2 0 0 2 2 1 0 FerA (NUC095) domain TPR_17 PF13431.6 ORY95714.1 - 0.14 12.6 0.1 79 4.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY95714.1 - 0.18 12.5 0.2 1.5 9.6 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY95714.1 - 0.21 12.5 5.7 2.3 9.3 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY95714.1 - 1.6 9.2 6.5 28 5.3 0.9 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY95714.1 - 6.9 6.8 8.1 0.69 10.0 0.3 3.3 4 0 0 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat BCDHK_Adom3 PF10436.9 ORY95715.1 - 4.7e-44 150.1 1.9 9.3e-44 149.1 1.9 1.5 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY95715.1 - 1.4e-09 38.5 0.0 2.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ORY95715.1 - 0.04 13.9 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Lipase_3 PF01764.25 ORY95716.1 - 6.6e-10 39.0 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY95716.1 - 0.013 16.2 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY95716.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY95716.1 - 0.088 12.4 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 ORY95716.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 ORY95716.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 ORY95716.1 - 0.16 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Mito_carr PF00153.27 ORY95718.1 - 4.2e-34 116.4 6.9 3.3e-12 46.1 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ligase_CoA PF00549.19 ORY95720.1 - 0.0018 18.1 0.0 1.4 8.7 0.0 2.0 1 1 1 2 2 2 2 CoA-ligase Death PF00531.22 ORY95720.1 - 0.079 13.1 0.0 1.3 9.3 0.0 2.0 2 0 0 2 2 2 0 Death domain stn_TNFRSF12A PF12191.8 ORY95720.1 - 0.13 12.5 0.1 3.9 7.7 0.0 2.0 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Ligase_CoA PF00549.19 ORY95721.1 - 0.0013 18.6 0.0 0.58 10.0 0.0 2.0 1 1 1 2 2 2 2 CoA-ligase DUF2878 PF11086.8 ORY95721.1 - 0.052 13.8 2.1 8.6 6.5 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2878) stn_TNFRSF12A PF12191.8 ORY95721.1 - 0.055 13.7 0.1 2.3 8.4 0.0 2.0 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Rep-A_N PF04057.12 ORY95721.1 - 0.062 13.3 0.1 4.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Death PF00531.22 ORY95721.1 - 0.11 12.7 0.0 7 6.9 0.0 2.1 2 0 0 2 2 2 0 Death domain SRC-1 PF08832.10 ORY95723.1 - 5.9 8.0 7.1 0.24 12.5 0.7 1.9 3 0 0 3 3 3 0 Steroid receptor coactivator IBR PF01485.21 ORY95727.1 - 9.7e-19 67.4 45.4 2.4e-11 43.7 3.6 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORY95727.1 - 1.9e-07 30.8 35.8 5.2e-05 23.0 3.9 4.7 3 2 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY95727.1 - 0.00031 21.0 48.7 0.014 15.7 8.8 4.3 2 1 1 3 3 3 3 Ring finger domain zf-RING_UBOX PF13445.6 ORY95727.1 - 0.00046 20.2 6.4 0.00046 20.2 6.4 4.1 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY95727.1 - 0.0013 18.5 1.9 0.0013 18.5 1.9 5.0 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) DUF1541 PF07563.11 ORY95727.1 - 0.062 13.2 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Rgp1 PF08737.10 ORY95727.1 - 0.11 11.7 0.2 0.22 10.7 0.2 1.4 2 0 0 2 2 2 0 Rgp1 DUF4795 PF16043.5 ORY95727.1 - 0.17 11.5 3.9 0.31 10.6 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) zf-C3HC4_4 PF15227.6 ORY95727.1 - 0.45 10.7 33.7 0.2 11.9 6.2 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING MKT1_C PF12246.8 ORY95728.1 - 9.2e-18 64.4 0.0 1e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_C PF12246.8 ORY95729.1 - 6.2e-10 38.7 0.0 9.3e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 ORY95730.1 - 3.3e-07 30.7 0.0 6.1e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 XPG N-terminal domain W2 PF02020.18 ORY95731.1 - 6.7e-13 48.6 2.2 6.7e-13 48.6 2.2 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DivIC PF04977.15 ORY95731.1 - 0.041 13.6 0.6 0.041 13.6 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator Fungal_TACC PF12709.7 ORY95731.1 - 0.091 13.2 2.5 12 6.4 0.2 2.4 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cnn_1N PF07989.11 ORY95731.1 - 0.13 12.4 3.8 0.44 10.7 3.8 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Prominin PF05478.11 ORY95731.1 - 0.2 9.6 2.2 0.31 8.9 2.2 1.2 1 0 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 ORY95731.1 - 0.43 10.0 6.9 0.85 9.0 6.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 SDA1 PF05285.12 ORY95731.1 - 5.4 6.3 29.7 1.6 8.1 10.4 2.2 2 0 0 2 2 2 0 SDA1 MBOAT_2 PF13813.6 ORY95732.1 - 3.3e-15 56.1 2.5 8.1e-15 54.9 2.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PPR_2 PF13041.6 ORY95733.1 - 3e-22 78.5 0.0 1.4e-11 44.4 0.0 8.3 9 2 2 11 11 11 3 PPR repeat family PPR_3 PF13812.6 ORY95733.1 - 5e-19 68.1 0.1 6.6e-08 32.5 0.0 6.4 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.20 ORY95733.1 - 1.7e-14 52.9 0.1 1e-05 25.4 0.0 8.6 9 0 0 9 9 9 2 PPR repeat PPR_1 PF12854.7 ORY95733.1 - 5.7e-14 51.5 0.0 2.4e-08 33.5 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 ORY95733.1 - 2.6e-08 33.5 0.1 0.00033 20.1 0.0 3.5 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORY95733.1 - 0.0031 18.2 18.4 18 6.5 0.0 8.4 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY95733.1 - 0.0099 16.4 4.9 15 6.2 0.2 5.1 4 2 1 5 5 5 1 Tetratricopeptide repeat RPAP3_C PF13877.6 ORY95733.1 - 0.13 12.8 0.0 4.9 7.8 0.0 3.3 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 TPR_10 PF13374.6 ORY95733.1 - 1.2 9.1 4.2 4.5 7.3 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Eaf7 PF07904.13 ORY95734.1 - 2.6e-21 76.0 0.2 4.3e-21 75.3 0.2 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 CCDC53 PF10152.9 ORY95734.1 - 0.28 11.6 4.4 1.4 9.4 4.6 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3736 PF12540.8 ORY95734.1 - 0.39 10.8 10.1 0.065 13.3 6.2 1.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3736) TFIIF_alpha PF05793.12 ORY95734.1 - 0.69 8.4 15.5 0.88 8.1 15.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 ORY95734.1 - 1.8 7.0 4.3 2 6.9 4.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF908 PF06012.12 ORY95734.1 - 4.1 6.7 5.9 5.9 6.2 5.8 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) SRP-alpha_N PF04086.13 ORY95734.1 - 6.1 6.7 11.3 7.7 6.3 11.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FA_desaturase PF00487.24 ORY95735.1 - 2.9e-28 99.4 23.5 5.2e-28 98.6 23.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ORY95735.1 - 1.9e-08 34.6 0.0 4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Bystin PF05291.11 ORY95736.1 - 1.4e-140 467.7 1.3 2.1e-140 467.1 1.3 1.2 1 0 0 1 1 1 1 Bystin Hemocyanin_M PF00372.19 ORY95736.1 - 0.021 14.0 0.2 0.035 13.3 0.2 1.3 1 0 0 1 1 1 0 Hemocyanin, copper containing domain PNISR PF15996.5 ORY95736.1 - 0.16 12.2 3.3 0.32 11.3 3.3 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR YpjP PF14005.6 ORY95736.1 - 0.46 10.5 6.3 2.8 8.0 0.1 2.9 3 0 0 3 3 3 0 YpjP-like protein SNRNP27 PF08648.12 ORY95737.1 - 4.1e-30 103.6 1.1 4.8e-30 103.4 1.1 1.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins SMAP PF15477.6 ORY95737.1 - 0.071 14.1 0.2 0.088 13.8 0.2 1.1 1 0 0 1 1 1 0 Small acidic protein family Nop16 PF09420.10 ORY95738.1 - 5.7e-54 183.3 12.3 6.5e-54 183.2 12.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF4297 PF14130.6 ORY95738.1 - 0.0024 18.1 2.1 0.0028 17.8 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4297) NTP_transf_4 PF13562.6 ORY95738.1 - 0.076 13.2 0.8 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Sugar nucleotidyl transferase CHZ PF09649.10 ORY95738.1 - 0.13 11.8 0.7 0.26 10.8 0.7 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ EHN PF06441.12 ORY95738.1 - 0.17 12.3 1.7 0.22 11.9 0.1 2.0 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Spt20 PF12090.8 ORY95739.1 - 1.7 8.2 15.2 2.8 7.5 15.2 1.4 1 0 0 1 1 1 0 Spt20 family HIT PF01230.23 ORY95741.1 - 4.5e-23 81.8 0.3 6e-23 81.4 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORY95741.1 - 5.4e-11 43.0 0.1 7.6e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORY95741.1 - 3.5e-06 26.9 0.1 5.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF726 PF05277.12 ORY95743.1 - 1e-85 287.7 0.0 1.3e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF2309 PF10070.9 ORY95743.1 - 0.0041 15.5 0.2 0.0054 15.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) MCU PF04678.13 ORY95743.1 - 0.087 12.9 0.4 0.22 11.6 0.3 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Phage_holin_3_6 PF07332.11 ORY95743.1 - 3.8 7.6 9.9 0.55 10.3 4.8 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 ORY95744.1 - 2.2e-26 92.8 0.0 3.1e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY95744.1 - 1.9e-12 47.0 0.0 2.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY95744.1 - 4.7e-08 32.2 0.0 4.7e-08 32.2 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Epimerase PF01370.21 ORY95745.1 - 5.2e-52 176.7 0.0 6.1e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY95745.1 - 1.7e-44 152.6 0.0 2.4e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY95745.1 - 7.8e-16 57.9 0.0 6.3e-14 51.6 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY95745.1 - 6.2e-13 48.5 0.0 3.2e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY95745.1 - 5.6e-09 35.5 0.0 8e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORY95745.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORY95745.1 - 2.4e-06 27.2 0.0 5.2e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ORY95745.1 - 4.9e-06 25.9 0.0 0.00013 21.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ORY95745.1 - 6.3e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY95745.1 - 9.1e-05 22.1 0.0 0.0049 16.5 0.0 2.5 2 1 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 ORY95745.1 - 0.1 12.1 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_7 PF13241.6 ORY95745.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding IBR PF01485.21 ORY95746.1 - 1.2e-10 41.4 41.0 1e-07 32.1 10.7 4.8 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain TENA_THI-4 PF03070.16 ORY95746.1 - 0.066 13.0 0.0 0.19 11.5 0.0 1.7 1 1 1 2 2 2 0 TENA/THI-4/PQQC family zf-H2C2_2 PF13465.6 ORY95746.1 - 7 7.3 0.0 7 7.3 0.0 4.7 6 0 0 6 6 6 0 Zinc-finger double domain Topoisom_I PF01028.20 ORY95748.1 - 1.9e-97 325.1 2.9 1.9e-97 325.1 2.9 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 ORY95748.1 - 1.2e-94 315.8 2.6 1.2e-94 315.8 2.6 3.5 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 ORY95748.1 - 1e-32 111.9 5.0 4e-32 110.0 5.0 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Fungal_trans PF04082.18 ORY95749.1 - 1.1e-30 106.6 0.0 5e-30 104.4 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY95749.1 - 9.7e-10 38.4 12.0 2e-09 37.4 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COMPASS-Shg1 PF05205.12 ORY95750.1 - 1.3e-17 64.4 0.9 1.6e-17 64.0 0.9 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF445 PF04286.12 ORY95750.1 - 0.081 12.7 0.4 0.099 12.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Catalase PF00199.19 ORY95751.1 - 1.4e-168 560.9 0.2 1.8e-168 560.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 ORY95751.1 - 2.6e-35 121.3 0.0 4.4e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ORY95751.1 - 6.7e-18 64.7 0.0 1.4e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 ORY95751.1 - 0.0022 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family RabGAP-TBC PF00566.18 ORY95752.1 - 1.5e-45 155.5 0.0 2.9e-45 154.6 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PknH_C PF14032.6 ORY95752.1 - 0.022 14.6 0.7 0.038 13.9 0.7 1.3 1 0 0 1 1 1 0 PknH-like extracellular domain CDC45 PF02724.14 ORY95752.1 - 0.15 10.3 1.0 0.24 9.6 1.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TMEM171 PF15471.6 ORY95752.1 - 1.3 7.9 3.6 2.5 7.0 3.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 adh_short_C2 PF13561.6 ORY95753.1 - 1.6e-53 181.7 0.0 2e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY95753.1 - 2.2e-49 167.6 0.0 3.3e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY95753.1 - 5.4e-09 36.2 0.0 7.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 KR domain TFIIB PF00382.19 ORY95753.1 - 0.017 15.1 0.1 0.062 13.4 0.0 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Epimerase PF01370.21 ORY95753.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY95753.1 - 0.21 10.9 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SET PF00856.28 ORY95754.1 - 4.8e-05 23.8 0.1 0.00024 21.5 0.1 1.9 1 1 0 1 1 1 1 SET domain CK1gamma_C PF12605.8 ORY95754.1 - 0.02 16.1 0.3 0.031 15.4 0.3 1.3 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal MCR_alpha_N PF02745.15 ORY95754.1 - 0.097 12.0 0.1 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Vezatin PF12632.7 ORY95755.1 - 9.2e-51 172.9 3.4 1.4e-50 172.3 3.4 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Flg_hook PF02120.16 ORY95755.1 - 0.033 14.1 0.4 0.21 11.5 0.1 2.4 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK Polysacc_synt_3 PF13440.6 ORY95755.1 - 0.12 11.6 0.1 0.25 10.5 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SURF1 PF02104.15 ORY95756.1 - 1.7e-48 165.2 0.4 2.2e-48 164.8 0.4 1.1 1 0 0 1 1 1 1 SURF1 family Dus PF01207.17 ORY95756.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Herpes_U5 PF05999.11 ORY95759.1 - 0.087 11.6 0.1 0.094 11.4 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus U5-like family EF-hand_4 PF12763.7 ORY95760.1 - 8e-34 115.7 0.0 3.8e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ORY95760.1 - 4.5e-05 22.7 0.0 0.0026 17.2 0.0 2.9 3 0 0 3 3 3 1 EF hand FlxA PF14282.6 ORY95760.1 - 0.00019 21.4 0.6 0.00019 21.4 0.6 3.9 3 1 1 4 4 3 2 FlxA-like protein TSC22 PF01166.18 ORY95760.1 - 0.0002 21.6 5.9 0.69 10.3 0.0 4.7 4 1 1 5 5 5 1 TSC-22/dip/bun family DUF1720 PF08226.11 ORY95760.1 - 0.00049 20.5 40.7 0.0033 17.8 15.2 3.8 2 1 2 4 4 3 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 ORY95760.1 - 0.0023 18.3 0.0 0.23 11.9 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair Phasin PF05597.11 ORY95760.1 - 0.0059 16.6 0.2 0.0059 16.6 0.2 2.5 3 1 0 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) EF-hand_6 PF13405.6 ORY95760.1 - 0.0074 16.1 0.0 9.7 6.4 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain ABC_tran_CTD PF16326.5 ORY95760.1 - 0.0094 16.2 0.6 0.0094 16.2 0.6 4.8 4 1 0 4 4 4 1 ABC transporter C-terminal domain Zw10 PF06248.13 ORY95760.1 - 0.042 12.4 3.6 0.088 11.4 3.6 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 E3_binding PF02817.17 ORY95760.1 - 0.073 13.4 0.1 0.26 11.7 0.1 2.0 1 0 0 1 1 1 0 e3 binding domain APG17 PF04108.12 ORY95760.1 - 0.11 11.6 8.5 0.066 12.3 1.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg17 NPV_P10 PF05531.12 ORY95760.1 - 0.26 11.8 7.2 5.2 7.6 0.3 3.7 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Ribosomal_L29 PF00831.23 ORY95760.1 - 0.73 9.8 8.1 26 4.9 0.0 4.5 4 0 0 4 4 4 0 Ribosomal L29 protein Spc7 PF08317.11 ORY95760.1 - 0.99 8.2 20.3 0.093 11.6 3.3 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein KASH_CCD PF14662.6 ORY95760.1 - 1 9.1 11.0 0.12 12.2 2.3 2.7 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 ORY95760.1 - 1.2 9.1 20.7 1.1 9.3 4.0 3.7 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 ORY95760.1 - 1.3 8.3 19.2 0.7 9.2 8.7 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 ORY95760.1 - 1.7 9.2 24.5 73 3.9 13.2 3.3 1 1 1 2 2 2 0 Apg6 coiled-coil region EMP24_GP25L PF01105.24 ORY95760.1 - 1.9 8.4 8.7 0.13 12.2 1.1 2.4 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD AAA_13 PF13166.6 ORY95760.1 - 2.1 6.9 11.6 0.11 11.1 1.4 2.2 1 1 0 2 2 2 0 AAA domain ATG16 PF08614.11 ORY95760.1 - 2.9 8.1 24.8 1.4 9.1 8.5 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TssO PF17561.2 ORY95760.1 - 5.5 7.1 8.6 2.5 8.2 0.7 2.8 3 0 0 3 3 3 0 Type VI secretion system, TssO LPP PF04728.13 ORY95760.1 - 5.8 7.4 10.1 16 6.0 0.0 4.8 4 1 0 4 4 4 0 Lipoprotein leucine-zipper Allexi_40kDa PF05549.11 ORY95760.1 - 6.4 6.2 7.5 11 5.4 0.9 2.7 2 1 0 2 2 2 0 Allexivirus 40kDa protein Peptidase_M3 PF01432.20 ORY95761.1 - 5.8e-121 404.9 0.0 1e-120 404.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 MMgT PF10270.9 ORY95762.1 - 3.4e-15 56.2 0.3 4.1e-15 56.0 0.3 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter KxDL PF10241.9 ORY95763.1 - 0.00066 19.9 3.0 0.00066 19.9 3.0 2.8 2 1 1 3 3 2 1 Uncharacterized conserved protein DUF1664 PF07889.12 ORY95763.1 - 0.026 14.5 6.7 0.04 14.0 5.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FAP PF07174.11 ORY95763.1 - 0.083 12.3 11.8 0.023 14.2 8.6 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Cortex-I_coil PF09304.10 ORY95763.1 - 0.12 12.6 6.5 0.32 11.2 6.5 1.8 1 0 0 1 1 1 0 Cortexillin I, coiled coil WXG100 PF06013.12 ORY95763.1 - 0.13 12.5 0.1 0.13 12.5 0.1 4.0 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Cep57_CLD_2 PF14197.6 ORY95763.1 - 0.15 12.1 7.6 0.14 12.2 5.1 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TFIIA PF03153.13 ORY95763.1 - 0.3 11.0 27.6 0.43 10.5 27.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_3 PF12776.7 ORY95763.1 - 0.38 11.8 5.4 15 6.7 0.6 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4407 PF14362.6 ORY95763.1 - 2.2 7.6 13.1 4.6 6.5 13.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IFT57 PF10498.9 ORY95763.1 - 2.3 7.1 14.6 5.3 5.9 14.6 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Macoilin PF09726.9 ORY95763.1 - 3.8 6.0 23.7 5.2 5.5 23.7 1.1 1 0 0 1 1 1 0 Macoilin family TBCA PF02970.16 ORY95763.1 - 4.2 7.8 12.1 0.34 11.3 6.2 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF3450 PF11932.8 ORY95763.1 - 5.4 6.2 19.4 0.51 9.6 14.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FUSC PF04632.12 ORY95763.1 - 5.8 5.3 7.4 8.8 4.7 7.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNase_3_N PF18497.1 ORY95764.1 - 0.031 14.5 0.4 0.12 12.6 0.3 1.8 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain eIF3_subunit PF08597.10 ORY95765.1 - 3.2e-55 187.7 43.6 3.6e-55 187.5 43.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit IL34 PF15036.6 ORY95765.1 - 0.51 10.4 3.1 0.17 11.9 0.2 1.7 2 0 0 2 2 2 0 Interleukin 34 CBP_BcsG PF11658.8 ORY95765.1 - 3.1 6.1 8.3 0.32 9.3 3.4 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG MTP18 PF10558.9 ORY95765.1 - 5.1 7.0 10.5 0.055 13.4 1.0 2.4 2 2 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) Methyltransf_25 PF13649.6 ORY95766.1 - 1.1e-13 51.6 0.0 5.1e-13 49.6 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY95766.1 - 5.5e-12 46.2 0.0 1.5e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY95766.1 - 5e-11 42.7 0.0 6.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY95766.1 - 1e-09 38.4 0.0 1.1e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY95766.1 - 4e-05 23.1 0.0 0.00014 21.3 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY95766.1 - 0.0038 18.0 0.0 0.01 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORY95766.1 - 0.005 16.7 0.0 0.009 15.9 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 ORY95766.1 - 0.0097 14.5 1.5 0.018 13.6 0.0 2.1 2 1 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 ORY95766.1 - 0.038 13.5 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase tRNA_int_endo PF01974.17 ORY95767.1 - 1.5e-18 66.6 0.1 4.7e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 ORY95767.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Kelch_4 PF13418.6 ORY95768.1 - 2.8e-22 78.5 5.2 1.3e-09 37.9 0.3 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY95768.1 - 3.8e-18 65.1 3.6 5.5e-08 32.6 0.1 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ORY95768.1 - 3.9e-16 58.9 10.6 1.8e-06 28.1 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY95768.1 - 3.5e-14 52.1 0.9 5.6e-07 29.0 0.0 3.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 ORY95768.1 - 9e-12 44.8 2.9 1.4e-06 28.3 0.0 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 ORY95768.1 - 6.3e-11 41.8 2.4 8.8e-07 28.7 0.0 3.6 4 0 0 4 4 4 2 Kelch motif NPV_P10 PF05531.12 ORY95768.1 - 0.026 15.0 3.6 0.27 11.7 2.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 ORY95768.1 - 0.048 12.3 17.9 0.064 11.9 17.9 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 ORY95768.1 - 0.41 10.7 4.9 0.24 11.4 1.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRCC36_C PF18110.1 ORY95768.1 - 6.7 6.9 9.0 0.61 10.3 2.6 2.4 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain HSP70 PF00012.20 ORY95769.1 - 1.9e-103 346.7 0.5 2.5e-103 346.3 0.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY95769.1 - 3.4e-13 49.1 0.1 6.4e-13 48.2 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Pam16 PF03656.13 ORY95770.1 - 1.6e-34 118.7 3.4 1.9e-34 118.4 3.4 1.0 1 0 0 1 1 1 1 Pam16 Thg1C PF14413.6 ORY95770.1 - 0.1 12.8 2.1 0.15 12.2 2.1 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain Cons_hypoth698 PF03601.14 ORY95771.1 - 1.5e-38 132.4 9.3 3.9e-32 111.4 8.5 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 698 Glt_symporter PF03616.14 ORY95771.1 - 0.017 13.9 10.4 0.025 13.3 4.1 2.2 2 0 0 2 2 2 0 Sodium/glutamate symporter GPR_Gpa2_C PF11970.8 ORY95771.1 - 0.071 13.2 0.3 1.6 8.9 0.1 2.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Ferlin_C PF16165.5 ORY95771.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.4 3 1 1 4 4 4 0 Ferlin C-terminus MadM PF03818.13 ORY95771.1 - 0.35 10.8 7.2 1.3 9.0 0.4 3.8 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit RRM_2 PF04059.12 ORY95772.1 - 5.7e-42 141.8 0.5 7.2e-42 141.5 0.5 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 ORY95772.1 - 0.012 15.4 0.1 0.045 13.6 0.1 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 ORY95772.1 - 0.034 14.4 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 Peptidase_M24 PF00557.24 ORY95773.1 - 2.2e-57 194.2 0.0 2.9e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY95773.1 - 4.3e-24 84.6 0.1 1.3e-23 83.1 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 ORY95773.1 - 0.17 11.9 0.1 0.43 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) adh_short PF00106.25 ORY95777.1 - 2.7e-45 154.2 3.0 3.9e-45 153.7 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY95777.1 - 2e-38 132.2 1.5 2.9e-38 131.8 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY95777.1 - 2.1e-07 31.1 1.8 3.4e-07 30.3 1.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY95777.1 - 0.063 12.7 0.4 0.11 11.9 0.4 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PCSK9_C1 PF18459.1 ORY95777.1 - 0.12 12.5 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain HECT PF00632.25 ORY95778.1 - 6.9e-98 327.9 0.0 1.3e-97 327.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 ORY95778.1 - 4.1e-93 312.3 0.1 4.1e-93 312.3 0.1 8.1 9 0 0 9 9 9 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 ORY95778.1 - 2.6e-65 221.2 11.5 2.6e-65 221.2 11.5 5.7 5 2 0 5 5 5 1 Domain of Unknown Function (DUF908) UBM PF14377.6 ORY95778.1 - 7.8e-19 66.5 3.4 1.4e-08 33.9 0.1 3.3 2 0 0 2 2 2 2 Ubiquitin binding region UBA PF00627.31 ORY95778.1 - 7.9e-08 32.1 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Folliculin PF11704.8 ORY95778.1 - 6.1 6.7 9.3 5.1 6.9 0.1 3.9 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport NARP1 PF12569.8 ORY95778.1 - 6.5 5.5 24.7 5.8 5.7 2.4 2.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 CLTH PF10607.9 ORY95779.1 - 1.6e-31 109.2 0.6 2.8e-31 108.4 0.1 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 ORY95779.1 - 7.2e-10 38.7 0.4 1.4e-09 37.8 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY95779.1 - 1.1e-05 25.3 0.7 1.9e-05 24.5 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY95779.1 - 0.0001 22.5 1.1 0.00019 21.7 1.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORY95779.1 - 0.00036 20.3 0.6 0.00081 19.2 0.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY95779.1 - 0.0013 18.6 1.1 0.0025 17.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY95779.1 - 0.002 18.0 1.3 0.0039 17.0 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY95779.1 - 0.0025 17.9 1.1 0.0063 16.6 1.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_PEP_C PF04513.12 ORY95779.1 - 0.047 13.7 0.9 0.12 12.4 0.8 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C3HC4_2 PF13923.6 ORY95779.1 - 0.13 12.1 2.8 0.5 10.3 2.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fzo_mitofusin PF04799.13 ORY95779.1 - 3.5 7.2 6.2 1.4 8.4 1.8 2.3 2 1 1 3 3 3 0 fzo-like conserved region Syntaxin-6_N PF09177.11 ORY95779.1 - 5.7 7.6 6.6 15 6.2 0.3 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Synaptobrevin PF00957.21 ORY95780.1 - 6.4e-15 54.7 0.7 1.2e-14 53.9 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY95780.1 - 1.3e-11 44.3 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 ORY95780.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region VTC PF09359.10 ORY95784.1 - 8.6e-102 340.2 0.1 1.5e-101 339.4 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 ORY95784.1 - 7.2e-17 62.4 12.6 5.3e-06 26.6 0.1 4.2 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 ORY95784.1 - 1e-14 54.7 1.1 2.3e-14 53.6 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) CTNNBL PF08216.11 ORY95784.1 - 0.16 12.2 0.5 0.39 10.9 0.1 1.8 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Apt1 PF10351.9 ORY95785.1 - 0.031 13.1 9.1 0.037 12.9 9.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 ORY95785.1 - 0.056 11.7 18.4 0.069 11.4 18.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 ORY95785.1 - 1.3 8.2 8.9 1.7 7.8 8.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 ORY95785.1 - 1.3 7.7 19.3 1.9 7.2 19.3 1.2 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 ORY95785.1 - 1.5 7.5 16.3 2.2 6.9 16.3 1.2 1 0 0 1 1 1 0 Raftlin Sec62 PF03839.16 ORY95785.1 - 2.4 7.6 17.3 4.9 6.6 17.3 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Ndc1_Nup PF09531.10 ORY95785.1 - 2.8 6.5 8.5 3.1 6.4 8.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 ORY95785.1 - 3 6.8 16.2 4.2 6.3 16.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 ORY95785.1 - 7.2 5.5 19.7 11 4.9 19.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR3 PF03666.13 ORY95785.1 - 7.5 5.2 19.5 11 4.6 19.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 WD40 PF00400.32 ORY95786.1 - 2.2e-37 126.4 23.1 1.9e-09 37.9 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY95786.1 - 8.3e-14 51.7 0.0 0.031 14.6 0.0 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY95786.1 - 0.0046 16.0 0.1 3.1 6.7 0.0 3.6 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY95786.1 - 0.0072 15.7 0.0 1.1 8.5 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 ORY95786.1 - 0.09 11.4 0.1 4 6.0 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SASA PF03629.18 ORY95787.1 - 8.1e-48 163.0 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase FUSC_2 PF13515.6 ORY95788.1 - 1.6e-16 60.6 10.5 1.6e-16 60.6 10.5 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 ORY95788.1 - 1.1e-15 57.7 1.7 1.1e-15 57.7 1.7 3.0 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ORY95788.1 - 3e-13 49.4 2.3 3e-13 49.4 2.3 2.8 2 1 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 ORY95788.1 - 1.3e-12 48.0 1.2 1.3e-12 48.0 1.2 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ORY95788.1 - 2.7e-07 29.5 16.0 3.5e-07 29.2 5.3 3.1 3 0 0 3 3 3 2 Fusaric acid resistance protein family BSD PF03909.17 ORY95791.1 - 8.8e-12 44.8 0.8 2.2e-11 43.6 0.8 1.7 1 0 0 1 1 1 1 BSD domain Prominin PF05478.11 ORY95791.1 - 0.079 10.9 0.1 0.11 10.5 0.1 1.1 1 0 0 1 1 1 0 Prominin DAO PF01266.24 ORY95792.1 - 2e-61 208.6 0.5 2.3e-61 208.4 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY95792.1 - 5.4e-07 29.1 0.3 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY95792.1 - 1.8e-05 24.9 0.2 4.6e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY95792.1 - 3.8e-05 23.7 0.8 0.093 12.7 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ORY95792.1 - 9.9e-05 21.4 5.4 0.015 14.2 5.4 2.1 1 1 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 ORY95792.1 - 0.00017 20.9 2.1 0.0006 19.1 0.5 2.1 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 ORY95792.1 - 0.00068 19.3 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 ORY95792.1 - 0.00087 18.6 1.8 0.004 16.5 1.8 1.9 1 1 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 ORY95792.1 - 0.0019 18.4 0.3 0.0067 16.7 0.3 1.9 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Amino_oxidase PF01593.24 ORY95792.1 - 0.0021 17.4 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.22 ORY95792.1 - 0.0029 16.8 1.3 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY95792.1 - 0.0035 17.9 0.8 0.027 15.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY95792.1 - 0.013 14.6 6.0 0.58 9.2 6.0 2.1 1 1 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 ORY95792.1 - 0.023 14.9 0.3 0.093 13.0 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 ORY95792.1 - 0.11 12.4 0.5 0.25 11.2 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mqo PF06039.15 ORY95792.1 - 0.21 10.1 0.1 9.5 4.6 0.1 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 ORY95792.1 - 0.25 10.0 2.2 9.7 4.8 0.8 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 ORY95792.1 - 0.52 9.3 1.5 3.4 6.6 0.3 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein DNA_pol_A_exo1 PF01612.20 ORY95793.1 - 4.4e-15 55.8 0.0 7.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DUF5633 PF18656.1 ORY95793.1 - 6.7 6.7 7.9 1.2 9.0 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DUF4679 PF15728.5 ORY95793.1 - 7.4 5.5 11.1 1.2 8.1 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4679) CLP1_P PF16575.5 ORY95794.1 - 1.2e-50 171.9 0.0 2.3e-50 171.0 0.0 1.5 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 ORY95794.1 - 1.1e-34 119.3 0.0 1.9e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 ORY95794.1 - 1.8e-33 114.6 0.0 4.1e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 ORY95794.1 - 0.0013 18.8 0.0 0.0083 16.2 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 ORY95794.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY95794.1 - 0.025 13.9 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_35 PF14516.6 ORY95794.1 - 0.031 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Roc PF08477.13 ORY95794.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 ORY95794.1 - 0.088 12.2 0.0 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein ATP_bind_1 PF03029.17 ORY95794.1 - 0.12 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RuvB_N PF05496.12 ORY95794.1 - 0.12 12.1 0.9 5.8 6.6 0.0 2.5 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ORY95794.1 - 0.13 12.0 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY95794.1 - 0.19 12.1 0.0 0.32 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain UPF0172 PF03665.13 ORY95795.1 - 2.8e-50 171.0 0.2 3.3e-50 170.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 ORY95795.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Lectin_leg-like PF03388.13 ORY95796.1 - 9.8e-61 205.0 0.0 1.3e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 ORY95796.1 - 0.012 15.1 0.0 0.19 11.2 0.0 2.2 1 1 1 2 2 2 0 Legume lectin domain Aa_trans PF01490.18 ORY95797.1 - 1.4e-64 218.3 29.6 1.9e-64 217.9 29.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPR_11 PF13414.6 ORY95798.1 - 1.3e-11 44.0 10.4 0.004 16.8 0.0 5.8 6 0 0 6 6 6 3 TPR repeat TPR_16 PF13432.6 ORY95798.1 - 1.7e-08 34.9 6.0 0.028 15.1 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY95798.1 - 1.9e-06 28.3 11.9 0.22 12.1 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY95798.1 - 1.9e-05 24.5 5.5 9.7e-05 22.2 1.3 3.2 2 1 2 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.6 ORY95798.1 - 0.00027 21.1 1.4 62 4.3 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat SF-assemblin PF06705.11 ORY95798.1 - 0.091 12.1 5.2 0.2 11.0 5.0 1.7 1 1 0 1 1 1 0 SF-assemblin/beta giardin TPR_7 PF13176.6 ORY95798.1 - 0.34 11.0 3.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY95798.1 - 0.81 10.1 10.8 31 5.1 0.3 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY95798.1 - 1.1 10.3 10.6 38 5.5 0.2 6.3 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY95798.1 - 2.6 8.0 17.4 8.1 6.5 0.2 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY95798.1 - 4.2 7.7 21.9 1.7 8.9 0.2 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat Syntaxin PF00804.25 ORY95799.1 - 4.2e-36 124.5 16.6 6.4e-36 123.9 16.6 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY95799.1 - 1.2e-09 38.0 1.6 3.1e-09 36.7 1.6 1.8 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 ORY95799.1 - 1.2e-06 26.9 6.1 1.5e-06 26.5 6.1 1.1 1 0 0 1 1 1 1 Prominin Syntaxin_2 PF14523.6 ORY95799.1 - 0.0001 22.6 9.1 0.0001 22.6 9.1 2.2 2 0 0 2 2 2 1 Syntaxin-like protein ISG65-75 PF11727.8 ORY95799.1 - 0.0035 16.6 0.7 0.0035 16.6 0.7 1.8 2 0 0 2 2 2 1 Invariant surface glycoprotein MCU PF04678.13 ORY95799.1 - 0.016 15.3 0.6 0.016 15.3 0.6 2.5 2 1 0 2 2 2 0 Mitochondrial calcium uniporter Vac_Fusion PF02346.16 ORY95799.1 - 0.018 14.6 4.1 0.026 14.1 0.3 2.5 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 SKA1 PF07160.12 ORY95799.1 - 0.018 14.9 1.1 0.018 14.9 1.1 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 RPW8 PF05659.11 ORY95799.1 - 0.065 12.9 1.0 0.89 9.2 0.1 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Synaptobrevin PF00957.21 ORY95799.1 - 0.074 12.8 11.1 0.065 13.0 0.6 3.1 3 1 0 3 3 3 0 Synaptobrevin LXG PF04740.12 ORY95799.1 - 0.11 12.2 12.1 0.039 13.7 6.9 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF1512 PF07431.12 ORY95799.1 - 0.31 10.0 4.4 0.36 9.8 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1512) Allexi_40kDa PF05549.11 ORY95799.1 - 0.76 9.2 8.9 0.13 11.7 2.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein LMBR1 PF04791.16 ORY95799.1 - 0.77 8.6 13.2 1.4 7.8 13.2 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4094 PF13334.6 ORY95799.1 - 1.1 9.8 5.4 7.1 7.1 5.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) CENP-K PF11802.8 ORY95799.1 - 1.1 8.8 14.0 0.12 12.0 6.4 2.1 1 1 0 2 2 2 0 Centromere-associated protein K DotU PF09850.9 ORY95799.1 - 2.6 7.7 6.4 1 9.0 0.1 2.7 2 1 0 2 2 2 0 Type VI secretion system protein DotU Fib_alpha PF08702.10 ORY95799.1 - 3.3 7.9 19.1 5.8 7.1 6.0 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Herpes_LMP1 PF05297.11 ORY95800.1 - 0.22 10.7 1.3 0.25 10.5 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1977 PF09320.11 ORY95801.1 - 1.2e-22 80.1 0.0 1.2e-22 80.1 0.0 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 ORY95801.1 - 1.7e-22 79.3 1.2 1.7e-22 79.3 1.2 2.0 3 0 0 3 3 3 1 DnaJ domain TPR_2 PF07719.17 ORY95801.1 - 0.0092 16.0 0.0 0.053 13.7 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3128 PF11326.8 ORY95802.1 - 9.8e-20 70.7 2.5 1.4e-19 70.3 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Cmc1 PF08583.10 ORY95802.1 - 0.03 14.3 0.8 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-RING_2 PF13639.6 ORY95803.1 - 2.8e-14 53.1 7.5 5.9e-14 52.1 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY95803.1 - 2.3e-10 40.0 3.4 2.3e-10 40.0 3.4 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY95803.1 - 2.5e-09 36.8 2.4 2.5e-09 36.8 2.4 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY95803.1 - 1.9e-08 34.0 7.3 3.6e-08 33.1 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY95803.1 - 1.3e-06 28.5 11.2 6.8e-06 26.3 11.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 ORY95803.1 - 2.2e-06 27.6 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 ORY95803.1 - 9.6e-05 22.3 6.3 9.6e-05 22.3 6.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY95803.1 - 0.00035 20.6 1.4 0.00035 20.6 1.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY95803.1 - 0.00063 19.8 7.5 0.0014 18.6 7.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY95803.1 - 0.011 15.6 11.3 0.017 14.9 11.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2681 PF10883.8 ORY95803.1 - 0.023 15.1 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) zf-RING_4 PF14570.6 ORY95803.1 - 0.024 14.4 5.6 0.046 13.5 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORY95803.1 - 0.027 14.6 3.5 0.069 13.3 3.5 1.7 1 1 0 1 1 1 0 RING-variant domain DUF2339 PF10101.9 ORY95803.1 - 0.063 11.9 0.2 0.074 11.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Prok-RING_4 PF14447.6 ORY95803.1 - 0.081 12.8 10.7 0.21 11.5 10.7 1.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 ORY95803.1 - 1 9.6 11.7 7.6 6.8 11.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 ORY95803.1 - 1.5 8.8 11.2 0.64 10.0 7.0 2.2 1 1 1 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 ORY95803.1 - 8.4 6.1 12.1 17 5.1 12.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type vMSA PF00695.19 ORY95805.1 - 0.064 12.4 2.6 0.076 12.1 2.6 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Metallophos PF00149.28 ORY95807.1 - 2e-14 54.6 1.4 4e-14 53.6 1.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY95807.1 - 0.0018 18.5 0.8 0.03 14.5 0.8 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FAD_binding_3 PF01494.19 ORY95808.1 - 1.7e-21 76.9 0.2 9.7e-21 74.4 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY95808.1 - 0.00016 21.4 0.0 0.059 12.9 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY95808.1 - 0.00035 19.9 0.0 0.058 12.6 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ORY95808.1 - 0.00036 20.4 0.0 0.00089 19.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 ORY95808.1 - 0.00081 18.5 0.0 0.013 14.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORY95808.1 - 0.0041 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORY95808.1 - 0.013 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY95808.1 - 0.037 14.6 0.0 0.31 11.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORY95808.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 ORY95808.1 - 0.085 12.1 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 ORY95809.1 - 3.5e-11 43.5 15.8 6.9e-05 23.5 0.1 6.0 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY95809.1 - 2.4e-07 31.0 0.1 0.0013 19.0 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3642 PF12182.8 ORY95809.1 - 0.035 14.4 0.1 0.099 12.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial lipoprotein Mito_carr PF00153.27 ORY95810.1 - 1.1e-76 252.8 0.7 4.4e-27 93.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 ORY95810.1 - 3.6e-07 29.2 0.0 0.0027 17.1 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 ORY95810.1 - 4.3e-07 29.1 0.1 0.00096 18.5 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY95810.1 - 6.1e-07 28.9 0.2 0.00034 20.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 ORY95810.1 - 3.2e-06 27.5 0.0 6.8e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain pair Serine_protease PF18405.1 ORY95810.1 - 9.6e-06 24.9 0.5 0.12 11.5 0.0 3.3 4 0 0 4 4 4 2 Gammaproteobacterial serine protease EF-hand_8 PF13833.6 ORY95810.1 - 0.019 14.8 0.0 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair GPR15L PF15854.5 ORY95813.1 - 0.0099 16.1 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 G-protein coupled receptor ligand 15 Zn_clus PF00172.18 ORY95815.1 - 0.00022 21.3 11.1 0.00022 21.3 11.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORY95815.1 - 0.0017 18.4 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold RskA PF10099.9 ORY95815.1 - 0.0087 16.4 7.7 0.0087 16.4 7.7 2.0 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DUF846 PF05832.12 ORY95816.1 - 2.3e-56 189.7 14.6 2.8e-56 189.4 14.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 ORY95816.1 - 0.019 15.3 6.8 0.9 9.9 2.0 2.3 2 0 0 2 2 2 0 YwiC-like protein DUF4191 PF13829.6 ORY95816.1 - 0.98 8.7 5.5 1.2 8.4 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF1430 PF07242.11 ORY95816.1 - 1.6 9.0 8.0 3.5 7.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) UPF0014 PF03649.13 ORY95816.1 - 2 7.7 8.1 0.3 10.4 1.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) RseC_MucC PF04246.12 ORY95816.1 - 6.7 6.7 10.1 12 5.9 1.5 2.4 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EI24 PF07264.11 ORY95818.1 - 5.5e-22 78.9 9.2 7.3e-22 78.5 9.2 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) GTP_EFTU PF00009.27 ORY95819.1 - 5e-35 120.8 0.0 7.7e-34 116.9 0.0 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY95819.1 - 6.7e-19 68.0 1.0 2.1e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 ORY95819.1 - 6.9e-14 52.0 7.1 3.3e-10 40.2 0.1 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 ORY95819.1 - 4.5e-10 39.3 0.7 1.7e-09 37.5 0.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 ORY95819.1 - 1.6e-06 28.2 0.2 9.8e-06 25.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 ORY95819.1 - 1.7e-05 25.0 0.0 4.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ORY95819.1 - 0.00028 20.8 2.6 0.00084 19.2 0.0 3.0 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Ras PF00071.22 ORY95819.1 - 0.02 14.5 0.0 0.13 11.9 0.0 2.4 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 ORY95819.1 - 0.53 10.6 4.5 0.68 10.2 0.2 3.2 2 1 0 2 2 2 0 AAA domain Beta-Casp PF10996.8 ORY95820.1 - 8e-26 90.5 0.0 8.4e-25 87.2 0.0 2.4 2 1 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 ORY95820.1 - 9.1e-24 84.0 0.0 2.5e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 ORY95820.1 - 9.8e-16 57.4 0.0 2.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 ORY95820.1 - 1.5e-13 51.3 0.0 4.2e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY95820.1 - 1.2e-11 44.5 0.0 1.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORY95820.1 - 0.0038 16.5 0.0 0.0072 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 ORY95820.1 - 0.0063 16.4 0.0 0.026 14.4 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain CSTF2_hinge PF14327.6 ORY95821.1 - 1.5e-23 83.0 2.7 1.5e-23 83.0 2.7 2.6 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 ORY95821.1 - 8.6e-22 76.8 0.1 2e-21 75.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 ORY95821.1 - 5.1e-12 45.2 12.3 5.1e-12 45.2 12.3 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 ORY95821.1 - 0.0016 18.6 0.1 0.004 17.3 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif Spo7_2_N PF15407.6 ORY95821.1 - 0.079 12.6 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Sporulation protein family 7 Septin PF00735.18 ORY95822.1 - 5.5e-54 183.3 0.1 1.1e-39 136.4 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 ORY95822.1 - 4.7e-06 26.6 0.1 3.6e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY95822.1 - 0.00019 21.4 0.6 0.12 12.2 0.4 2.9 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY95822.1 - 0.00019 21.8 0.1 0.00033 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 ORY95822.1 - 0.0023 17.5 0.1 0.034 13.7 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY95822.1 - 0.0026 18.0 0.1 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORY95822.1 - 0.004 17.7 0.0 0.0075 16.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Roc PF08477.13 ORY95822.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 ORY95822.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ORY95822.1 - 0.017 15.0 0.2 0.063 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 ORY95822.1 - 0.032 13.9 0.1 0.071 12.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 ORY95822.1 - 0.033 13.7 0.1 0.056 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 ORY95822.1 - 0.039 13.1 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MCM PF00493.23 ORY95822.1 - 0.057 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 ORY95822.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Ras PF00071.22 ORY95822.1 - 0.062 12.9 0.1 0.27 10.8 0.1 2.1 1 1 0 1 1 1 0 Ras family AAA PF00004.29 ORY95822.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-grasp_4 PF13535.6 ORY95822.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain AAA_5 PF07728.14 ORY95822.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORY95822.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 ORY95822.1 - 0.15 11.1 0.0 1.3 8.1 0.0 2.3 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 ORY95822.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Clat_adaptor_s PF01217.20 ORY95823.1 - 1.4e-53 180.6 2.3 1.7e-53 180.4 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 ORY95823.1 - 0.051 12.6 0.2 0.084 11.9 0.2 1.3 1 1 0 1 1 1 0 Trafficking protein Mon1 C2 PF00168.30 ORY95824.1 - 3.3e-16 59.4 0.0 7.3e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 ORY95824.1 - 9.1e-14 51.9 2.8 3.3e-09 37.1 2.0 2.7 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 ORY95824.1 - 3.8e-13 48.9 2.5 3.4e-09 35.8 0.1 3.2 4 0 0 4 4 4 2 Plant family of unknown function (DUF810) DUF3387 PF11867.8 ORY95824.1 - 0.18 11.1 1.4 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3387) Uteroglobin PF01099.17 ORY95824.1 - 0.2 12.0 0.5 1.7 9.1 0.1 2.7 3 0 0 3 3 3 0 Uteroglobin family RIX1 PF08167.12 ORY95825.1 - 4e-25 88.7 7.3 2.7e-24 86.0 4.5 2.8 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis KR PF08659.10 ORY95825.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain stn_TNFRSF12A PF12191.8 ORY95827.1 - 0.012 15.8 0.1 5.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2878 PF11086.8 ORY95827.1 - 0.022 15.0 2.0 2.1 8.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2878) Ligase_CoA PF00549.19 ORY95827.1 - 0.036 13.9 0.0 8.2 6.2 0.0 2.1 1 1 1 2 2 2 0 CoA-ligase UL45 PF05473.12 ORY95827.1 - 0.043 13.5 3.0 2.8 7.6 0.7 2.0 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Rep-A_N PF04057.12 ORY95827.1 - 0.093 12.8 0.3 5.4 7.1 0.1 2.1 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain TPT PF03151.16 ORY95827.1 - 0.12 11.7 1.3 1.6 8.0 0.1 2.0 1 1 1 2 2 2 0 Triose-phosphate Transporter family Phage_holin_5_1 PF06946.11 ORY95827.1 - 0.3 11.5 1.8 13 6.3 0.3 2.0 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 CathepsinC_exc PF08773.11 ORY95828.1 - 0.16 12.3 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Cathepsin C exclusion domain DnaJ PF00226.31 ORY95829.1 - 1.8e-20 72.8 0.4 5e-20 71.4 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain ERG4_ERG24 PF01222.17 ORY95830.1 - 4.3e-148 493.6 12.9 4.9e-148 493.4 12.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY95830.1 - 0.0064 16.0 0.1 0.0064 16.0 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) GAT PF03127.14 ORY95831.1 - 0.00037 20.8 0.5 0.00052 20.3 0.5 1.2 1 0 0 1 1 1 1 GAT domain Spore_II_R PF09551.10 ORY95832.1 - 0.026 15.0 3.1 0.029 14.8 0.7 2.3 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) MnmE_helical PF12631.7 ORY95832.1 - 0.26 11.4 5.4 0.15 12.2 0.9 2.5 1 1 1 2 2 2 0 MnmE helical domain TPR_6 PF13174.6 ORY95832.1 - 0.38 11.5 1.6 37 5.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4407 PF14362.6 ORY95832.1 - 1.2 8.4 5.4 1.6 8.0 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 ORY95832.1 - 3.3 8.1 8.2 2.8 8.3 4.8 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4404 PF14357.6 ORY95832.1 - 4.4 8.0 7.2 3.3 8.4 0.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 ORY95832.1 - 5.9 7.0 5.7 7 6.7 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nop14 PF04147.12 ORY95833.1 - 0.0042 15.4 4.5 0.0068 14.7 4.5 1.2 1 0 0 1 1 1 1 Nop14-like family Ribosomal_60s PF00428.19 ORY95833.1 - 0.11 13.1 0.2 2.5 8.8 0.1 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein SEEEED PF14797.6 ORY95833.1 - 0.25 11.5 12.0 0.85 9.8 12.0 1.9 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex LIM PF00412.22 ORY95834.1 - 3.8e-10 39.8 6.0 4.5e-10 39.6 6.0 1.1 1 0 0 1 1 1 1 LIM domain Metallothio_Pro PF02069.16 ORY95834.1 - 0.071 13.4 3.3 1.1 9.5 0.5 2.3 1 1 1 2 2 2 0 Prokaryotic metallothionein Mak10 PF04112.13 ORY95835.1 - 2.7e-53 179.9 0.4 4.6e-53 179.2 0.4 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF390 PF04094.14 ORY95835.1 - 0.16 10.2 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF3449 PF11931.8 ORY95836.1 - 2.3e-80 268.8 5.7 6.2e-80 267.3 2.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 ORY95836.1 - 7.3e-24 84.1 2.3 7.3e-24 84.1 2.3 2.6 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 ORY95836.1 - 4.8e-12 45.5 0.2 4.8e-12 45.5 0.2 2.4 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 ORY95836.1 - 6.1e-08 32.8 4.0 4.5e-05 23.7 1.8 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY95836.1 - 1.9e-06 28.0 1.8 1.9e-06 28.0 1.8 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY95836.1 - 0.025 14.9 1.8 0.025 14.9 1.8 3.3 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORY95836.1 - 0.054 14.4 2.5 13 7.0 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DBF PF07535.12 ORY95836.1 - 0.063 13.4 0.6 0.063 13.4 0.6 4.0 4 1 0 4 4 4 0 DBF zinc finger OrsD PF12013.8 ORY95836.1 - 0.08 13.4 0.6 0.38 11.2 0.1 2.4 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Neugrin PF06413.11 ORY95836.1 - 4.4 7.3 8.2 3.3 7.7 0.1 2.6 2 1 0 2 2 2 0 Neugrin Na_H_Exchanger PF00999.21 ORY95837.1 - 1.2e-55 188.9 25.0 1.5e-55 188.6 25.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY95837.1 - 2.8 8.1 5.4 0.57 10.3 0.8 2.3 2 0 0 2 2 2 0 YrhC-like protein PfkB PF00294.24 ORY95838.1 - 8.9e-32 110.6 1.3 1.7e-23 83.4 0.0 2.1 1 1 1 2 2 2 2 pfkB family carbohydrate kinase WD40 PF00400.32 ORY95839.1 - 4.1e-44 147.7 21.0 3e-06 27.8 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 ORY95839.1 - 1.5e-10 40.7 3.0 7.4e-09 35.3 0.5 2.5 1 1 1 2 2 2 2 F-box domain F-box-like PF12937.7 ORY95839.1 - 9.3e-10 38.2 3.2 1.8e-09 37.3 3.2 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORY95839.1 - 5.4e-09 36.2 0.9 0.98 9.8 0.0 5.6 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY95839.1 - 0.00079 19.1 0.0 0.12 11.9 0.0 2.5 2 1 0 2 2 2 1 PQQ-like domain WD40_like PF17005.5 ORY95839.1 - 0.002 17.5 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain F-box_4 PF15966.5 ORY95839.1 - 0.0039 17.1 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 F-box Nup160 PF11715.8 ORY95839.1 - 0.015 14.0 3.6 1.6 7.3 0.0 3.5 4 1 0 5 5 5 0 Nucleoporin Nup120/160 SecA_PP_bind PF01043.20 ORY95839.1 - 0.16 12.6 0.0 1.1 10.0 0.0 2.2 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Sulfotransfer_4 PF17784.1 ORY95840.1 - 3e-50 171.0 0.0 3.4e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95840.1 - 2.2e-06 28.2 0.4 3.3e-05 24.4 0.1 2.4 2 1 1 3 3 3 1 Sulfotransferase family Lipase_3 PF01764.25 ORY95840.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PhoLip_ATPase_C PF16212.5 ORY95841.1 - 4.6e-50 170.7 21.8 4.6e-50 170.7 21.8 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY95841.1 - 5e-17 61.3 5.6 1.3e-16 60.0 5.6 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 ORY95841.1 - 2.1e-15 56.7 0.3 7.9e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY95841.1 - 4.8e-13 49.9 0.1 9.7e-08 32.5 0.2 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY95841.1 - 2.6e-09 37.0 0.3 5e-08 32.9 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY95841.1 - 8.5e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 ORY95841.1 - 3.4 7.8 10.7 1.1 9.4 4.5 3.1 3 0 0 3 3 3 0 C-terminus of AA_permease RNA_pol_Rpb1_1 PF04997.12 ORY95842.1 - 2.1e-117 391.9 0.0 3.9e-117 391.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ORY95842.1 - 1.9e-106 355.4 0.5 4e-106 354.3 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY95842.1 - 2.2e-76 255.7 1.2 3.2e-76 255.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 ORY95842.1 - 4.1e-65 219.2 1.4 5.4e-65 218.8 0.1 2.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 ORY95842.1 - 4.3e-51 173.0 0.0 1e-50 171.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 ORY95842.1 - 1.1e-49 167.9 5.4 2.5e-49 166.7 5.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 ORY95842.1 - 4.6e-39 132.7 0.8 1.5e-38 131.1 0.8 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 ORY95842.1 - 2.5e-11 43.3 336.5 0.4 11.1 16.2 16.7 5 2 1 17 17 17 14 RNA polymerase Rpb1 C-terminal repeat ANAPC4_WD40 PF12894.7 ORY95843.1 - 3.3e-10 40.1 0.1 0.001 19.3 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY95843.1 - 6.1e-10 39.5 0.9 8.2e-05 23.3 0.0 4.6 5 0 0 5 5 4 2 WD domain, G-beta repeat Atg14 PF10186.9 ORY95843.1 - 0.0016 17.6 0.7 0.0025 17.0 0.7 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 eIF2A PF08662.11 ORY95843.1 - 0.0017 18.3 0.8 2.2 8.1 0.1 3.5 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF641 PF04859.12 ORY95843.1 - 0.0057 17.0 0.5 0.013 15.8 0.5 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Bacillus_HBL PF05791.11 ORY95843.1 - 0.011 15.6 1.5 0.019 14.8 1.5 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Tropomyosin_1 PF12718.7 ORY95843.1 - 0.015 15.5 5.0 0.025 14.7 5.0 1.2 1 0 0 1 1 1 0 Tropomyosin like DivIC PF04977.15 ORY95843.1 - 0.025 14.3 2.1 0.05 13.4 2.1 1.4 1 0 0 1 1 1 0 Septum formation initiator SKA1 PF07160.12 ORY95843.1 - 0.029 14.2 2.7 0.056 13.3 2.7 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TTKRSYEDQ PF10212.9 ORY95843.1 - 0.035 13.1 1.2 0.069 12.1 1.2 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 ORY95843.1 - 0.048 12.5 2.5 0.083 11.8 2.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 ORY95843.1 - 0.05 13.7 3.0 0.092 12.8 3.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 ORY95843.1 - 0.097 12.0 1.7 0.15 11.4 1.7 1.3 1 0 0 1 1 1 0 FAM76 protein Filament PF00038.21 ORY95843.1 - 0.11 12.1 3.3 0.17 11.5 3.3 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF16 PF01519.16 ORY95843.1 - 0.11 13.0 0.2 0.24 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 ORY95843.1 - 0.17 11.9 2.7 0.33 11.0 2.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 ORY95843.1 - 0.2 12.0 4.8 0.086 13.2 2.1 1.8 2 0 0 2 2 1 0 TSC-22/dip/bun family DUF4407 PF14362.6 ORY95843.1 - 0.22 10.8 1.7 0.33 10.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 ORY95843.1 - 0.23 12.1 3.7 0.54 10.9 3.7 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TEX13 PF15186.6 ORY95843.1 - 0.24 11.1 1.6 0.43 10.3 1.6 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family HAUS5 PF14817.6 ORY95843.1 - 0.41 9.3 4.1 0.59 8.8 4.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 VPS38 PF17649.1 ORY95843.1 - 0.59 8.9 4.0 13 4.5 0.0 2.1 1 1 1 2 2 2 0 Vacuolar protein sorting 38 GrpE PF01025.19 ORY95843.1 - 2.3 7.8 6.7 1 9.0 4.2 1.6 2 0 0 2 2 1 0 GrpE Sulfotransfer_4 PF17784.1 ORY95844.1 - 1.8e-53 181.6 0.0 2e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95844.1 - 5.3e-06 27.0 0.5 1.6e-05 25.4 0.4 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 ORY95845.1 - 1.7e-51 175.1 0.0 2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95845.1 - 1.6e-05 25.4 0.7 0.00018 22.0 0.1 2.4 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 ORY95846.1 - 2.7e-52 177.7 0.0 3e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY95846.1 - 0.0028 18.1 0.1 0.0082 16.5 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family IPK PF03770.16 ORY95847.1 - 9.4e-49 165.9 0.0 1.7e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF3682 PF12446.8 ORY95847.1 - 0.032 14.7 1.0 0.075 13.5 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SET PF00856.28 ORY95848.1 - 3.4e-12 47.1 0.2 1.2e-11 45.3 0.2 1.9 1 1 0 1 1 1 1 SET domain FYVE PF01363.21 ORY95848.1 - 0.0074 16.4 3.5 0.0074 16.4 3.5 1.9 2 0 0 2 2 2 1 FYVE zinc finger HTH_21 PF13276.6 ORY95848.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain Tom7 PF08038.12 ORY95849.1 - 7.8e-21 73.5 0.5 8.6e-21 73.3 0.5 1.0 1 0 0 1 1 1 1 TOM7 family F-box-like PF12937.7 ORY95850.1 - 3.9e-07 29.9 0.5 3.9e-07 29.9 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY95850.1 - 0.0044 16.9 0.2 0.013 15.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 ORY95850.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 F-box INTS2 PF14750.6 ORY95852.1 - 2.6e-84 283.6 10.0 3.5e-84 283.2 10.0 1.1 1 0 0 1 1 1 1 Integrator complex subunit 2 FHA PF00498.26 ORY95854.1 - 7.1e-15 55.1 0.3 1.2e-14 54.4 0.3 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY95854.1 - 3.6e-11 42.6 7.1 3.6e-11 42.6 7.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY95854.1 - 4.9e-09 36.4 7.5 8.9e-09 35.5 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY95854.1 - 2.5e-05 24.0 8.8 4.4e-05 23.2 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY95854.1 - 0.00011 21.9 7.3 0.0002 21.2 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY95854.1 - 0.00017 21.8 6.4 0.00046 20.4 6.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY95854.1 - 0.0049 16.9 6.3 0.0049 16.9 6.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY95854.1 - 0.0058 16.6 10.2 0.0099 15.8 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 ORY95854.1 - 0.011 16.1 0.0 0.032 14.5 0.0 1.8 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 ORY95854.1 - 0.048 13.5 8.0 0.073 12.9 8.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY95854.1 - 0.071 13.2 2.6 0.14 12.2 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 ORY95854.1 - 0.089 12.7 7.0 0.15 11.9 7.0 1.4 1 0 0 1 1 1 0 PHD-finger TMEM89 PF15098.6 ORY95855.1 - 0.018 15.2 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 TMEM89 protein family Arm PF00514.23 ORY95856.1 - 5.8e-95 308.8 17.3 2.2e-13 49.7 0.3 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY95856.1 - 7.1e-24 83.9 4.2 1.2e-06 28.9 0.0 6.7 6 1 1 7 7 6 4 HEAT-like repeat Arm_3 PF16186.5 ORY95856.1 - 8.9e-23 79.6 3.0 9.6e-22 76.3 4.0 2.2 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 ORY95856.1 - 1.1e-21 77.1 9.7 4.9e-21 75.0 9.9 2.1 2 0 0 2 2 1 1 Importin beta binding domain HEAT_2 PF13646.6 ORY95856.1 - 2.1e-19 69.7 0.1 2.3e-05 24.7 0.0 6.2 2 1 3 6 6 6 5 HEAT repeats HEAT PF02985.22 ORY95856.1 - 2.9e-19 67.5 0.8 0.0018 18.4 0.0 7.5 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 ORY95856.1 - 4.8e-10 39.3 0.0 0.013 14.9 0.2 4.2 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 ORY95856.1 - 2e-07 31.1 0.1 0.088 12.9 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 ORY95856.1 - 4.1e-07 29.0 0.2 0.00025 19.8 0.0 3.4 1 1 2 3 3 3 1 Adaptin N terminal region NopRA1 PF16201.5 ORY95856.1 - 3.7e-06 26.7 0.3 0.98 9.0 0.0 4.9 1 1 1 2 2 2 2 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 ORY95856.1 - 0.00071 19.8 3.2 0.9 9.8 0.1 4.4 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 DCB PF16213.5 ORY95856.1 - 0.011 15.3 0.4 0.047 13.4 0.1 2.2 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 Atx10homo_assoc PF09759.9 ORY95856.1 - 0.015 15.3 0.0 1.3 9.1 0.0 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain NEMP PF10225.9 ORY95856.1 - 0.18 11.5 2.2 0.47 10.1 2.2 1.7 1 1 0 1 1 1 0 NEMP family HEAT_PBS PF03130.16 ORY95856.1 - 0.2 12.4 1.6 29 5.7 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat ELH PF02323.15 ORY95856.1 - 0.53 9.6 5.7 0.87 8.9 5.7 1.3 1 0 0 1 1 1 0 Egg-laying hormone precursor zf-C2H2 PF00096.26 ORY95857.1 - 1.7e-09 37.6 6.7 0.021 15.3 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORY95857.1 - 1.3e-06 28.7 6.1 0.017 15.3 0.2 3.2 1 1 2 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORY95857.1 - 0.001 19.3 2.8 0.019 15.2 0.1 2.8 3 0 0 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 ORY95857.1 - 0.0015 19.2 18.7 0.17 12.8 0.1 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY95857.1 - 0.021 15.3 12.2 0.025 15.0 0.6 4.3 3 1 0 3 3 3 0 Zinc-finger double domain Zip PF02535.22 ORY95857.1 - 0.1 11.8 1.7 0.093 11.9 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spc7_N PF15402.6 ORY95857.1 - 0.48 8.6 6.3 0.66 8.2 6.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SelP_N PF04592.14 ORY95857.1 - 1.5 8.1 17.8 2.2 7.6 17.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 ORY95857.1 - 4 6.1 4.4 4.9 5.8 4.4 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 ORY95858.1 - 8.2e-27 93.6 14.4 9.5e-27 93.4 14.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3391 PF11871.8 ORY95858.1 - 0.11 13.0 0.7 0.18 12.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3138 PF11336.8 ORY95858.1 - 0.2 10.2 1.5 0.2 10.2 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3824 PF12868.7 ORY95858.1 - 8.6 7.0 6.7 13 6.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) HC2 PF07382.11 ORY95859.1 - 0.00076 19.6 0.2 0.0012 19.0 0.2 1.3 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 FAP PF07174.11 ORY95859.1 - 0.11 11.9 23.3 0.14 11.6 23.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RR_TM4-6 PF06459.12 ORY95859.1 - 0.66 9.7 4.3 0.72 9.6 4.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FGF-BP1 PF06473.12 ORY95859.1 - 6.2 6.6 5.1 8.2 6.2 5.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Prefoldin_2 PF01920.20 ORY95860.1 - 1.8e-23 82.5 17.8 2.2e-23 82.2 17.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Rh5 PF18515.1 ORY95860.1 - 0.00012 21.5 3.5 0.00013 21.4 3.5 1.1 1 0 0 1 1 1 1 Rh5 coiled-coil domain Occludin_ELL PF07303.13 ORY95860.1 - 0.0017 19.1 12.4 0.15 12.8 2.9 2.1 2 0 0 2 2 2 2 Occludin homology domain Prefoldin PF02996.17 ORY95860.1 - 0.0028 17.6 12.9 0.0034 17.3 3.3 2.2 2 0 0 2 2 2 1 Prefoldin subunit Zwint PF15556.6 ORY95860.1 - 0.0087 15.6 4.1 0.0087 15.6 4.1 2.0 2 0 0 2 2 2 1 ZW10 interactor End3 PF12761.7 ORY95860.1 - 0.027 14.6 14.9 0.036 14.2 14.9 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Tropomyosin_1 PF12718.7 ORY95860.1 - 0.044 13.9 20.1 0.58 10.3 6.3 2.1 2 0 0 2 2 2 0 Tropomyosin like SpecificRecomb PF10136.9 ORY95860.1 - 0.052 11.9 7.4 0.053 11.8 7.4 1.0 1 0 0 1 1 1 0 Site-specific recombinase FlaC_arch PF05377.11 ORY95860.1 - 0.092 13.2 12.0 0.99 9.9 2.3 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) MCC-bdg_PDZ PF10506.9 ORY95860.1 - 0.1 12.6 0.9 0.1 12.6 0.9 2.8 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Sec8_exocyst PF04048.14 ORY95860.1 - 0.16 11.9 8.7 0.66 9.8 8.2 1.9 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.11 ORY95860.1 - 0.17 10.7 19.4 0.22 10.4 19.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TssO PF17561.2 ORY95860.1 - 0.53 10.4 8.1 3.7 7.6 0.3 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO GAS PF13851.6 ORY95860.1 - 0.57 9.5 22.3 0.55 9.5 7.0 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 ORY95860.1 - 0.6 10.1 20.6 0.78 9.8 9.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 ORY95860.1 - 0.7 9.9 12.3 0.55 10.3 3.8 2.1 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 ORY95860.1 - 0.87 10.1 8.9 5.1 7.6 2.0 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MCU PF04678.13 ORY95860.1 - 1.2 9.3 11.6 6.9 6.7 11.6 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Plasmid_RAQPRD PF09686.10 ORY95860.1 - 1.4 9.2 9.1 0.25 11.6 1.0 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Fib_alpha PF08702.10 ORY95860.1 - 1.6 8.9 11.5 0.68 10.1 2.2 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 ORY95860.1 - 1.7 8.1 6.8 1.2 8.6 3.5 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein Spc24 PF08286.11 ORY95860.1 - 1.7 8.9 16.9 4.1 7.7 5.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 POTRA_TamA_1 PF17243.2 ORY95860.1 - 1.9 8.7 6.3 0.47 10.6 0.9 2.2 2 0 0 2 2 2 0 POTRA domain TamA domain 1 Exonuc_VII_L PF02601.15 ORY95860.1 - 2.5 7.6 10.4 3 7.3 10.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 ORY95860.1 - 2.6 8.7 15.7 5.3 7.7 4.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_Maf PF03131.17 ORY95860.1 - 2.6 8.6 14.6 0.53 10.8 3.5 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor TRAF_BIRC3_bd PF16673.5 ORY95860.1 - 3.2 7.6 12.1 0.057 13.2 2.9 2.5 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain FlxA PF14282.6 ORY95860.1 - 3.5 7.7 19.6 0.31 11.0 6.7 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF4349 PF14257.6 ORY95860.1 - 4 6.8 9.9 0.3 10.5 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF1690 PF07956.11 ORY95860.1 - 4.4 7.7 15.9 6.6 7.2 15.9 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Sas10_Utp3 PF04000.15 ORY95860.1 - 6.4 7.5 8.8 1.4 9.6 0.6 2.3 2 1 0 2 2 2 0 Sas10/Utp3/C1D family DUF4337 PF14235.6 ORY95860.1 - 6.4 6.9 16.6 0.31 11.1 5.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Atg14 PF10186.9 ORY95860.1 - 7 5.6 15.9 21 4.1 15.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 ORY95860.1 - 8 6.9 19.3 9.2 6.7 5.1 2.8 2 2 1 3 3 3 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 ORY95860.1 - 9.2 6.6 23.8 1.1 9.5 8.8 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain Ribosomal_L2_C PF03947.18 ORY95861.1 - 1.5e-44 151.2 3.7 2.4e-44 150.6 3.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY95861.1 - 4.5e-15 55.4 0.1 1e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WD40 PF00400.32 ORY95862.1 - 1.5e-41 139.6 24.8 2.9e-06 27.9 1.1 13.4 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY95862.1 - 1.5e-11 44.4 4.4 0.0092 16.3 0.0 6.5 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY95862.1 - 0.0076 16.2 0.1 18 5.4 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 ORY95862.1 - 0.019 14.2 1.6 0.14 11.4 0.0 2.6 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NifU_N PF01592.16 ORY95863.1 - 2.3e-54 183.0 0.1 2.9e-54 182.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_60s PF00428.19 ORY95863.1 - 0.029 15.0 3.3 0.051 14.2 3.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPT PF03151.16 ORY95864.1 - 1.2e-05 24.9 4.4 1.2e-05 24.9 4.4 1.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF4175 PF13779.6 ORY95864.1 - 0.0007 17.7 5.1 0.001 17.1 5.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Spt20 PF12090.8 ORY95864.1 - 0.00075 19.2 15.6 0.001 18.8 15.6 1.1 1 0 0 1 1 1 1 Spt20 family EamA PF00892.20 ORY95864.1 - 0.0023 18.1 21.1 0.056 13.6 2.6 2.5 2 0 0 2 2 2 2 EamA-like transporter family DUF4834 PF16118.5 ORY95864.1 - 0.011 16.7 1.4 0.038 14.9 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CRT-like PF08627.10 ORY95864.1 - 0.02 13.9 0.4 0.02 13.9 0.4 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Pex14_N PF04695.13 ORY95864.1 - 0.033 14.9 6.8 0.081 13.6 6.8 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.8 ORY95864.1 - 0.045 12.6 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 ORY95864.1 - 0.063 12.9 1.0 0.16 11.6 0.3 1.8 2 0 0 2 2 2 0 FAM176 family TFIIA PF03153.13 ORY95864.1 - 0.11 12.4 17.7 0.14 12.1 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 ORY95864.1 - 0.16 12.0 6.3 0.22 11.5 6.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 ORY95864.1 - 0.17 9.8 3.2 0.24 9.3 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2722 PF10846.8 ORY95864.1 - 0.54 9.1 18.0 0.73 8.7 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 ORY95864.1 - 4.1 6.3 25.9 5.7 5.8 25.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4407 PF14362.6 ORY95864.1 - 6.6 6.0 9.5 0.35 10.2 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SAS4 PF15460.6 ORY95865.1 - 2.2e-08 34.1 4.0 4.7e-08 33.0 4.0 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 RRM_1 PF00076.22 ORY95866.1 - 4.7e-32 109.6 0.0 1e-14 54.0 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY95866.1 - 0.00056 19.9 0.1 1.3 9.1 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY95866.1 - 0.00073 19.6 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 ORY95866.1 - 0.049 13.5 0.0 4.8 7.1 0.0 3.7 4 1 0 4 4 4 0 Occluded RNA-recognition motif COQ9 PF08511.11 ORY95867.1 - 7.8e-29 99.3 0.2 1.4e-28 98.5 0.2 1.4 1 0 0 1 1 1 1 COQ9 Peptidase_C13 PF01650.18 ORY95868.1 - 9.7e-44 149.8 0.7 1.2e-43 149.5 0.7 1.0 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 ORY95868.1 - 0.0056 16.9 0.1 0.023 15.0 0.0 2.0 2 0 0 2 2 2 1 Mid domain of argonaute Pkinase PF00069.25 ORY95869.1 - 6.6e-37 127.3 0.0 4.6e-36 124.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY95869.1 - 4.1e-14 52.5 0.0 7.9e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY95869.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Ion_trans PF00520.31 ORY95870.1 - 3.9e-28 98.3 23.4 5.4e-28 97.9 23.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 ORY95870.1 - 2.1e-10 40.4 10.6 2.1e-10 40.4 10.6 2.7 2 1 1 3 3 3 1 Ion channel DUF697 PF05128.12 ORY95870.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF697) SUIM_assoc PF16619.5 ORY95870.1 - 0.21 11.7 9.2 9.7 6.4 5.8 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_A24 PF01478.18 ORY95870.1 - 2.1 8.8 6.1 0.38 11.2 2.1 1.8 2 0 0 2 2 2 0 Type IV leader peptidase family PBP1_TM PF14812.6 ORY95870.1 - 3.3 8.1 6.9 0.38 11.1 0.8 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 ORY95870.1 - 4.3 7.6 7.7 19 5.6 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AGTRAP PF06396.11 ORY95870.1 - 7.4 6.4 8.9 0.28 11.0 0.5 2.6 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) CAP PF00188.26 ORY95871.1 - 6.5e-22 78.7 3.4 6.5e-22 78.7 3.4 2.6 2 2 0 2 2 2 1 Cysteine-rich secretory protein family Apt1 PF10351.9 ORY95871.1 - 0.3 9.9 11.1 0.33 9.8 11.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 ORY95871.1 - 0.32 9.5 13.1 0.35 9.4 13.1 1.0 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 ORY95871.1 - 0.51 9.5 13.2 0.55 9.4 13.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 ORY95871.1 - 2.2 8.1 14.6 3 7.7 14.6 1.2 1 0 0 1 1 1 0 SPX domain MAP65_ASE1 PF03999.12 ORY95871.1 - 2.5 6.7 9.8 3.2 6.4 9.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) EBP50_C PF09007.11 ORY95871.1 - 3.6 8.6 12.0 5.6 8.0 12.0 1.3 1 0 0 1 1 1 0 EBP50, C-terminal CAP PF00188.26 ORY95872.1 - 1.6e-12 48.4 1.7 1.8e-11 45.0 1.7 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Rotamase PF00639.21 ORY95872.1 - 0.0014 19.5 0.0 0.0019 19.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain MF_alpha_N PF05436.11 ORY95873.1 - 0.15 12.0 0.1 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus FAT PF02259.23 ORY95874.1 - 3.4e-122 408.0 4.7 3.4e-122 408.0 4.7 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORY95874.1 - 1.4e-73 247.8 0.1 2.6e-73 246.9 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 ORY95874.1 - 2.2e-63 213.0 8.4 7.6e-58 195.0 0.1 5.7 4 1 1 5 5 5 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 ORY95874.1 - 1.6e-45 153.6 1.2 1.6e-45 153.6 1.2 3.5 4 0 0 4 4 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 ORY95874.1 - 4e-17 61.7 1.0 1.2e-16 60.2 1.0 2.0 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 ORY95874.1 - 5.3e-13 49.2 16.7 0.01 16.2 0.0 9.8 9 1 1 10 10 9 3 HEAT repeats HEAT PF02985.22 ORY95874.1 - 8.7e-11 41.1 20.3 0.0069 16.5 0.0 11.2 12 0 0 12 12 10 2 HEAT repeat TPR_16 PF13432.6 ORY95874.1 - 3.7e-09 37.1 7.7 0.021 15.5 1.7 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Adaptin_N PF01602.20 ORY95874.1 - 3.8e-08 32.3 12.0 0.027 13.0 1.0 6.5 5 2 0 6 6 6 3 Adaptin N terminal region TPR_19 PF14559.6 ORY95874.1 - 9e-08 32.5 4.3 0.049 14.1 0.1 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Cnd1 PF12717.7 ORY95874.1 - 1.2e-05 25.4 5.8 0.0032 17.5 0.2 6.1 5 2 1 7 7 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY95874.1 - 3.4e-05 24.3 23.8 0.0033 17.9 0.2 9.7 12 1 1 13 13 9 2 HEAT-like repeat Tti2 PF10521.9 ORY95874.1 - 8.2e-05 22.3 4.3 1.1 8.7 0.1 4.7 2 1 1 3 3 3 1 Tti2 family MMS19_C PF12460.8 ORY95874.1 - 0.00013 21.2 1.7 0.033 13.3 0.2 3.6 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Sec7_N PF12783.7 ORY95874.1 - 0.0004 20.3 0.3 1 9.3 0.0 4.5 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_2 PF07719.17 ORY95874.1 - 0.0013 18.7 8.3 4.9 7.5 0.2 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY95874.1 - 0.019 15.2 2.3 0.93 9.8 0.0 3.8 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 T_hemolysin PF12261.8 ORY95874.1 - 0.024 14.4 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 1 0 Thermostable hemolysin Dopey_N PF04118.14 ORY95874.1 - 0.029 13.5 0.1 0.19 10.8 0.1 2.4 1 1 0 1 1 1 0 Dopey, N-terminal TPR_7 PF13176.6 ORY95874.1 - 0.032 14.3 6.8 0.45 10.7 0.3 4.2 3 1 0 3 3 2 0 Tetratricopeptide repeat TetR_C_30 PF17939.1 ORY95874.1 - 0.038 14.2 1.0 5.8 7.2 0.0 4.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain U3snoRNP10 PF12397.8 ORY95874.1 - 0.45 10.9 1.8 30 5.0 0.2 4.3 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Tfb4 PF03850.14 ORY95875.1 - 1.1e-100 336.7 2.1 1.3e-100 336.4 2.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF3039 PF11238.8 ORY95875.1 - 2.2 8.1 5.4 17 5.3 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3039) DnaJ_C PF01556.18 ORY95877.1 - 4.9e-38 130.5 0.0 6.5e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY95877.1 - 1.3e-25 89.2 5.7 1.3e-25 89.2 5.7 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY95877.1 - 3.1e-08 33.9 20.7 6.6e-08 32.8 20.7 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_CIII PF02085.16 ORY95877.1 - 0.014 15.7 2.6 0.033 14.5 2.6 1.6 1 0 0 1 1 1 0 Class III cytochrome C family Cytochrome_C7 PF14522.6 ORY95877.1 - 0.017 15.1 4.3 0.017 15.1 4.3 2.3 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c TackOD1 PF18551.1 ORY95877.1 - 0.57 9.8 2.7 9.7 5.8 2.0 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Cytochrom_c3_2 PF14537.6 ORY95877.1 - 4 8.0 10.0 26 5.4 10.0 2.2 1 1 0 1 1 1 0 Cytochrome c3 HypA PF01155.19 ORY95877.1 - 7.7 6.6 10.2 9.6 6.3 2.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DLIC PF05783.11 ORY95878.1 - 2.7e-69 234.3 9.8 4.9e-55 187.2 0.3 4.9 2 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 ORY95878.1 - 0.0092 16.4 0.0 0.03 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY95878.1 - 0.088 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY95878.1 - 0.088 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter zf-C2H2 PF00096.26 ORY95880.1 - 1.6e-09 37.7 22.3 7.8e-05 22.9 3.8 4.4 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY95880.1 - 7.3e-09 35.7 32.8 0.00036 21.1 3.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY95880.1 - 2.1e-08 34.2 8.3 5.1e-05 23.5 1.1 5.1 6 0 0 6 6 4 3 Zinc-finger double domain zf-C2HE PF16278.5 ORY95880.1 - 9.1e-07 29.2 9.6 0.027 14.9 0.5 3.7 1 1 2 3 3 3 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 ORY95880.1 - 0.0091 16.0 31.4 0.048 13.7 3.1 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger BolA PF01722.18 ORY95880.1 - 0.012 15.8 1.4 0.012 15.8 1.4 3.4 4 0 0 4 4 4 0 BolA-like protein zf-C2H2_jaz PF12171.8 ORY95880.1 - 0.094 13.0 11.3 1.3 9.4 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY95880.1 - 0.1 13.0 10.5 0.68 10.4 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORY95880.1 - 0.12 12.3 6.7 0.91 9.5 0.3 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DHC_N1 PF08385.12 ORY95880.1 - 0.19 10.3 5.5 3.2 6.3 0.1 2.0 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 FAA_hydro_N_2 PF18288.1 ORY95880.1 - 0.4 11.1 2.3 0.28 11.6 0.4 1.7 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DZR PF12773.7 ORY95880.1 - 0.76 9.8 5.7 10 6.2 5.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.12 ORY95880.1 - 1.2 9.4 10.5 12 6.2 10.2 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain Androgen_recep PF02166.16 ORY95880.1 - 2.2 7.0 9.8 4.4 6.0 9.8 1.4 1 0 0 1 1 1 0 Androgen receptor NPR3 PF03666.13 ORY95882.1 - 4.9e-41 141.0 1.7 2.5e-21 76.0 1.0 2.1 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 PIP5K PF01504.18 ORY95883.1 - 2.4e-96 322.2 0.1 2.4e-96 322.2 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase MOR2-PAG1_mid PF14228.6 ORY95884.1 - 5e-70 236.4 17.5 5.5e-30 103.8 1.1 3.3 2 1 1 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_C PF14225.6 ORY95884.1 - 7.6e-53 180.0 6.4 4.8e-52 177.3 0.0 3.7 5 0 0 5 5 5 1 Cell morphogenesis C-terminal MOR2-PAG1_N PF14222.6 ORY95884.1 - 1.1e-19 70.8 0.0 2.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal AbiJ_NTD4 PF18863.1 ORY95884.1 - 0.032 14.7 0.2 1.1 9.7 0.0 3.7 4 2 2 6 6 6 0 AbiJ N-terminal domain 4 ComZ PF10815.8 ORY95884.1 - 0.034 14.2 0.4 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 ComZ Ins_allergen_rp PF06757.13 ORY95884.1 - 0.08 12.9 0.1 4.6 7.2 0.0 3.3 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification HEAT_2 PF13646.6 ORY95884.1 - 0.5 10.8 7.7 28 5.2 0.0 5.5 6 0 0 6 6 6 0 HEAT repeats DUF962 PF06127.11 ORY95885.1 - 2e-22 79.1 2.5 2.9e-22 78.5 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Shisa PF13908.6 ORY95886.1 - 0.0032 17.7 0.6 0.0032 17.7 0.6 2.9 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator Plasmodium_Vir PF05795.11 ORY95886.1 - 0.0035 16.8 3.4 0.0074 15.8 3.4 1.5 1 0 0 1 1 1 1 Plasmodium vivax Vir protein EphA2_TM PF14575.6 ORY95886.1 - 0.0058 17.5 0.0 0.12 13.2 0.0 2.8 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain CbtA PF09490.10 ORY95886.1 - 0.035 13.9 0.2 0.072 12.9 0.1 1.6 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Trp_oprn_chp PF09534.10 ORY95886.1 - 0.037 13.8 1.0 0.14 11.9 0.2 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mid2 PF04478.12 ORY95886.1 - 0.14 12.0 0.8 0.39 10.5 0.7 1.8 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor PepSY_2 PF13670.6 ORY95886.1 - 0.22 11.5 4.7 6.6 6.8 0.5 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain GREB1 PF15782.5 ORY95886.1 - 1.8 5.6 13.2 2 5.4 13.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EVI2A PF05399.11 ORY95886.1 - 6 6.4 10.7 7 6.2 9.2 1.7 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF3712 PF12505.8 ORY95887.1 - 4.2e-09 36.7 0.0 1.9e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORY95887.1 - 0.052 14.1 0.0 13 6.4 0.0 3.4 3 1 1 4 4 4 0 Late embryogenesis abundant protein DUF3712 PF12505.8 ORY95888.1 - 3.3e-06 27.4 0.0 4.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) PH PF00169.29 ORY95889.1 - 0.021 15.3 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF2457 PF10446.9 ORY95889.1 - 1.7 7.7 8.0 3.3 6.7 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Phosphodiest PF01663.22 ORY95890.1 - 1.4e-12 47.9 0.7 1.9e-12 47.5 0.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY95890.1 - 3.8e-06 26.5 0.1 6.8e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ORY95890.1 - 0.00062 19.2 0.1 0.00083 18.8 0.1 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily PPR_2 PF13041.6 ORY95891.1 - 9.4e-21 73.8 0.5 2.4e-05 24.4 0.0 6.5 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 ORY95891.1 - 1.8e-10 40.7 0.1 0.0015 18.5 0.0 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 ORY95891.1 - 1.7e-09 37.3 7.1 1.4 9.3 0.0 7.7 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 ORY95891.1 - 2.3e-08 33.7 0.3 0.2 11.0 0.0 3.4 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY95891.1 - 0.0052 16.5 5.6 46 3.8 0.5 6.5 7 0 0 7 7 7 0 PPR repeat TPR_10 PF13374.6 ORY95891.1 - 0.0083 16.0 0.0 34 4.5 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY95891.1 - 0.013 15.5 0.1 0.08 13.0 0.1 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY95891.1 - 0.045 14.6 1.4 4.7 8.3 0.0 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat MMS19_C PF12460.8 ORY95891.1 - 0.074 12.1 0.1 4.3 6.4 0.0 2.2 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Retrotrans_gag PF03732.17 ORY95891.1 - 0.096 13.0 1.0 1.2 9.4 0.1 3.2 4 0 0 4 4 4 0 Retrotransposon gag protein TPR_19 PF14559.6 ORY95891.1 - 0.36 11.4 3.9 30 5.2 0.1 4.3 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY95891.1 - 5.7 6.9 5.6 46 4.1 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2069 PF09842.9 ORY95892.1 - 6.3 7.1 15.4 0.14 12.4 2.1 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2069) Ras PF00071.22 ORY95893.1 - 1.3e-54 184.1 0.1 1.5e-54 184.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY95893.1 - 1.8e-19 70.1 0.0 2.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY95893.1 - 8.4e-08 31.9 0.1 9.9e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY95893.1 - 2.6e-06 27.1 0.2 7.3e-06 25.7 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY95893.1 - 0.00026 21.0 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY95893.1 - 0.001 19.0 2.1 0.7 9.8 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 ORY95893.1 - 0.0019 17.5 0.1 1.2 8.3 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY95894.1 - 1.7e-58 196.8 0.0 2e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY95894.1 - 7.3e-21 74.6 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY95894.1 - 2e-08 33.9 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY95894.1 - 6.6e-06 25.8 0.0 1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY95894.1 - 0.00074 19.5 0.0 0.93 9.4 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY95894.1 - 0.0062 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORY95894.1 - 0.018 14.8 0.5 0.61 9.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CTP_transf_3 PF02348.19 ORY95894.1 - 0.024 14.5 0.1 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Cytidylyltransferase G-alpha PF00503.20 ORY95894.1 - 0.032 13.4 0.0 6.5 5.8 0.0 2.0 1 1 0 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 ORY95894.1 - 0.087 12.4 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B 4HBT_3 PF13622.6 ORY95895.1 - 1.5e-64 218.6 0.4 1.8e-64 218.4 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORY95895.1 - 1.3e-33 115.6 0.0 8.1e-25 87.2 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase TAL_FSA PF00923.19 ORY95896.1 - 9e-101 337.0 0.2 1e-100 336.8 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 ORY95898.1 - 5.4e-72 242.3 0.2 5.4e-72 242.3 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY95898.1 - 6.9e-51 173.0 0.2 6.9e-51 173.0 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 ORY95898.1 - 7.5e-21 74.3 0.0 2.4e-20 72.7 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORY95898.1 - 3.9e-14 53.0 0.2 8.7e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORY95898.1 - 5.2e-06 26.0 0.1 1.7e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY95898.1 - 0.0018 17.1 21.5 0.031 13.0 21.5 2.2 1 1 0 1 1 1 1 Fungal protein kinase PH_9 PF15410.6 ORY95898.1 - 0.0064 16.8 0.1 1.2 9.5 0.0 2.8 1 1 1 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 ORY95898.1 - 0.0072 16.7 5.0 0.42 11.0 0.0 3.2 2 1 1 3 3 3 2 Pleckstrin homology domain Haspin_kinase PF12330.8 ORY95898.1 - 0.059 12.3 3.4 0.21 10.5 3.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DDHD PF02862.17 ORY95898.1 - 1.1 9.4 4.9 2.2 8.4 4.9 1.6 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 ORY95898.1 - 1.3 7.2 24.0 2.2 6.5 24.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C58 PF03543.14 ORY95898.1 - 1.9 8.1 8.1 4.3 7.0 8.1 1.6 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Neur_chan_memb PF02932.16 ORY95898.1 - 2.2 8.3 9.3 4.5 7.3 9.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPR_12 PF13424.6 ORY95899.1 - 2.8e-12 46.8 11.9 2.6e-06 27.6 2.8 5.0 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY95899.1 - 2.5e-05 24.0 3.2 0.5 10.5 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY95899.1 - 3.8e-05 23.6 5.8 0.061 13.6 0.3 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY95899.1 - 4e-05 23.3 1.0 6.2 6.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY95899.1 - 0.00042 20.2 11.9 0.21 11.8 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY95899.1 - 0.0038 17.9 13.6 2.5 9.1 0.6 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY95899.1 - 0.0077 16.0 2.3 0.84 9.6 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 ORY95900.1 - 4.8e-09 36.5 4.4 1.2e-05 25.6 0.2 5.7 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 ORY95900.1 - 1.3e-07 31.2 8.8 0.32 11.4 0.0 7.7 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 ORY95900.1 - 5.2e-06 26.6 18.1 0.00017 21.7 0.4 5.7 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY95900.1 - 7.5e-05 23.1 12.1 1.1 9.9 0.0 6.6 7 0 0 7 7 7 3 HEAT-like repeat DUF4097 PF13349.6 ORY95901.1 - 0.00049 19.5 4.7 0.0012 18.2 4.2 2.0 1 1 0 1 1 1 1 Putative adhesin FYRN PF05964.14 ORY95902.1 - 4e-16 58.6 0.1 5.9e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY95902.1 - 1.3e-13 50.9 0.0 1.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 F/Y rich C-terminus DUF3759 PF12585.8 ORY95903.1 - 0.019 15.0 0.1 0.029 14.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3759) DAP3 PF10236.9 ORY95903.1 - 0.2 10.8 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF3759 PF12585.8 ORY95904.1 - 9.5e-33 112.1 8.2 1.1e-32 111.8 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) F-box PF00646.33 ORY95907.1 - 5.6e-05 22.9 0.3 5.6e-05 22.9 0.3 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY95907.1 - 0.0016 18.3 1.2 0.0016 18.3 1.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY95908.1 - 0.00022 21.0 0.1 0.00079 19.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY95908.1 - 0.00023 21.0 0.3 0.00082 19.2 0.3 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY95908.1 - 0.00041 20.7 3.1 0.51 10.8 0.0 5.0 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY95908.1 - 0.029 14.1 0.4 0.39 10.5 0.0 3.2 3 1 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.6 ORY95909.1 - 0.71 9.7 5.5 2.6 7.9 0.2 3.9 4 1 0 4 4 4 0 Leucine rich repeat TPR_14 PF13428.6 ORY95910.1 - 0.0034 18.1 0.8 0.095 13.6 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY95910.1 - 0.015 15.6 0.7 0.35 11.2 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ORY95910.1 - 0.03 14.3 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF4810 PF16068.5 ORY95910.1 - 0.058 13.9 0.0 0.12 13.0 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4810) TPR_2 PF07719.17 ORY95910.1 - 0.09 12.9 1.6 3.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CorA PF01544.18 ORY95911.1 - 1.2e-45 156.1 7.2 4e-44 151.1 7.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PTH2 PF01981.16 ORY95912.1 - 3.4e-47 159.5 0.1 4.4e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 MFS_1 PF07690.16 ORY95913.1 - 6.7e-44 150.2 21.5 8.5e-44 149.9 21.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY95913.1 - 0.00016 21.1 1.6 0.00016 21.1 1.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Phage_holin_5_1 PF06946.11 ORY95913.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.6 2 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 DUF3671 PF12420.8 ORY95913.1 - 0.88 9.7 3.1 23 5.1 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function FAM176 PF14851.6 ORY95915.1 - 0.48 10.1 2.2 2.9 7.5 1.1 2.5 2 1 0 2 2 2 0 FAM176 family Sas10_Utp3 PF04000.15 ORY95916.1 - 2e-07 31.5 0.3 3.9e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family LIM PF00412.22 ORY95917.1 - 1.3e-24 86.1 21.2 3.4e-12 46.4 6.9 2.2 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 ORY95917.1 - 0.0046 16.5 12.9 1.8 8.2 0.8 4.3 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger MDM1 PF15501.6 ORY95917.1 - 0.017 14.3 9.6 0.024 13.8 9.6 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 zf-ACC PF17848.1 ORY95917.1 - 0.47 10.6 0.1 0.47 10.6 0.1 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Churchill PF06573.11 ORY95917.1 - 3.9 7.8 8.6 0.75 10.1 0.3 2.3 2 0 0 2 2 2 0 Churchill protein Lin-8 PF03353.15 ORY95917.1 - 6 6.3 6.0 8.1 5.9 6.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HAD PF12710.7 ORY95918.1 - 1.1e-09 39.0 0.0 1.5e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pectate_lyase_3 PF12708.7 ORY95919.1 - 0.11 12.3 1.5 0.26 11.1 0.3 2.2 2 1 0 2 2 2 0 Pectate lyase superfamily protein SUIM_assoc PF16619.5 ORY95919.1 - 0.85 9.7 5.8 1.8 8.7 5.8 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ANTH PF07651.16 ORY95920.1 - 2e-50 171.4 2.5 2.5e-50 171.0 2.5 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 ORY95920.1 - 1.9e-08 34.4 0.3 3.5e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 ENTH domain PutA_N PF18083.1 ORY95920.1 - 0.059 13.4 0.3 4.4 7.4 0.0 2.9 2 1 1 3 3 3 0 Proline utilization A N-terminal domain CorA PF01544.18 ORY95920.1 - 0.12 11.7 3.4 0.092 12.0 1.0 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SKIP_SNW PF02731.15 ORY95921.1 - 3e-74 248.0 3.0 3e-74 248.0 3.0 2.6 2 0 0 2 2 2 1 SKIP/SNW domain SEEEED PF14797.6 ORY95921.1 - 1.5 9.0 25.8 0.73 10.0 20.1 2.6 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Mur_ligase_M PF08245.12 ORY95922.1 - 1.1e-09 38.5 0.0 3.7e-07 30.3 0.0 2.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ORY95922.1 - 0.009 16.2 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Tugs PF17840.1 ORY95922.1 - 0.034 14.3 0.1 0.24 11.6 0.1 2.5 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain Pyrophosphatase PF00719.19 ORY95924.1 - 5.9e-45 153.0 0.3 7.2e-45 152.7 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Lactate_perm PF02652.14 ORY95925.1 - 2.4e-127 425.8 35.6 1.2e-74 252.0 15.7 2.0 2 0 0 2 2 2 2 L-lactate permease Lsm_interact PF05391.11 ORY95926.1 - 0.0035 16.8 0.3 0.0035 16.8 0.3 2.6 3 0 0 3 3 3 1 Lsm interaction motif U3_assoc_6 PF08640.11 ORY95926.1 - 0.022 14.8 12.6 0.093 12.8 0.1 4.1 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 6 DUF4108 PF13390.6 ORY95926.1 - 0.11 12.4 2.8 0.35 10.8 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) PMSR PF01625.21 ORY95927.1 - 1.1e-62 210.8 2.3 1.3e-62 210.5 2.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CoA_binding_2 PF13380.6 ORY95928.1 - 1.2e-29 103.2 0.0 1.3e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CSN8_PSD8_EIF3K PF10075.9 ORY95929.1 - 1.9e-05 24.6 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family GCFC PF07842.12 ORY95930.1 - 3.2e-71 240.2 15.3 5.1e-71 239.5 15.3 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 ORY95930.1 - 2.4e-14 52.9 6.1 5.8e-14 51.7 6.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY95930.1 - 6.3e-09 35.8 3.8 1.8e-08 34.3 3.8 1.8 1 0 0 1 1 1 1 G-patch domain Acetyltransf_6 PF13480.7 ORY95930.1 - 0.4 10.8 3.4 0.4 10.8 0.9 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Stm1_N PF09598.10 ORY95930.1 - 3.4 8.6 8.3 2.1 9.3 0.2 2.8 2 1 0 2 2 2 0 Stm1 EI24 PF07264.11 ORY95932.1 - 1.3e-22 80.9 23.9 1.6e-22 80.6 23.9 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2070 PF09843.9 ORY95932.1 - 7.7 4.7 10.3 9.1 4.4 10.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SPT16 PF08644.11 ORY95933.1 - 7.2e-56 188.6 0.0 7.2e-56 188.6 0.0 2.4 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 ORY95933.1 - 1e-41 142.4 2.2 2.3e-41 141.3 2.2 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 ORY95933.1 - 7.1e-28 97.7 0.0 1.3e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 ORY95933.1 - 2.1e-15 56.9 0.0 5.8e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like ATP-synt_Eps PF04627.13 ORY95934.1 - 4.9e-21 74.5 0.7 5.7e-21 74.2 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DNA_pol_B PF00136.21 ORY95935.1 - 3.5e-94 316.1 0.0 4.3e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 ORY95935.1 - 2.7e-13 50.2 10.2 4.4e-13 49.5 10.2 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ORY95935.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral OrfB_Zn_ribbon PF07282.11 ORY95935.1 - 1.9 8.4 5.6 0.24 11.4 1.2 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DNA_pol_B_exo1 PF03104.19 ORY95936.1 - 2.5e-21 76.2 0.0 7.9e-13 48.2 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain DUF3877 PF12993.7 ORY95938.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Glyco_hydro_63 PF03200.16 ORY95939.1 - 2.6e-170 567.4 2.1 3.5e-169 563.7 2.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 ORY95939.1 - 2e-42 145.8 0.0 4.3e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 ORY95939.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 ORY95939.1 - 0.051 12.4 0.1 0.089 11.6 0.1 1.3 1 0 0 1 1 1 0 Trehalase Na_Ca_ex PF01699.24 ORY95940.1 - 1.1e-45 155.3 43.1 1.6e-23 83.3 20.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CrgA PF06781.12 ORY95940.1 - 0.78 9.8 5.1 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Cell division protein CrgA SWIRM-assoc_2 PF16496.5 ORY95941.1 - 9e-42 143.4 2.2 9e-42 143.4 2.2 3.1 3 0 0 3 3 3 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 ORY95941.1 - 4.9e-29 100.5 0.1 2e-28 98.6 0.1 2.1 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 ORY95941.1 - 2.8e-12 46.6 0.1 2.8e-12 46.6 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 ORY95941.1 - 1.5e-10 40.9 13.4 1.5e-10 40.9 13.4 2.8 3 0 0 3 3 3 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 ORY95941.1 - 6.6e-08 32.7 0.5 2.4e-07 30.9 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain BRCT_2 PF16589.5 ORY95941.1 - 6.2e-05 23.3 0.4 0.0015 18.9 0.4 2.6 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Totivirus_coat PF05518.11 ORY95941.1 - 0.5 8.3 14.5 0.83 7.6 14.5 1.3 1 0 0 1 1 1 0 Totivirus coat protein FtsJ PF01728.19 ORY95942.1 - 2.8e-68 229.5 0.0 3.4e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DOT1 PF08123.13 ORY95943.1 - 6.5e-71 238.1 0.1 8.8e-71 237.7 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 ORY95943.1 - 1.8e-05 25.3 0.1 5.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY95943.1 - 4.4e-05 23.3 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY95943.1 - 0.00059 20.4 0.0 0.0018 18.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY95943.1 - 0.0006 19.2 0.1 0.0015 17.9 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 ORY95943.1 - 0.0011 19.7 0.4 0.0069 17.1 0.4 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY95943.1 - 0.0023 17.8 0.0 0.0056 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY95943.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 ORY95943.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase MARVEL PF01284.23 ORY95944.1 - 0.0013 18.8 8.9 0.002 18.2 8.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain ABC_export PF16962.5 ORY95944.1 - 0.0033 15.9 2.4 0.0042 15.6 2.4 1.1 1 0 0 1 1 1 1 Putative ABC exporter RDD PF06271.12 ORY95944.1 - 3.7 7.8 11.0 0.25 11.5 0.8 2.1 1 1 1 2 2 2 0 RDD family Glycos_transf_4 PF00953.21 ORY95945.1 - 5.9e-32 110.9 12.9 5.9e-32 110.9 12.9 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.32 ORY95946.1 - 8.8e-12 45.4 2.0 0.43 11.5 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY95946.1 - 0.0031 17.8 0.3 14 6.1 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BRCT PF00533.26 ORY95946.1 - 0.039 14.3 0.6 0.2 12.1 0.3 2.5 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Actin PF00022.19 ORY95947.1 - 4.5e-151 503.1 0.0 5.1e-151 502.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY95947.1 - 0.00011 21.1 0.0 0.014 14.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Tam41_Mmp37 PF09139.11 ORY95948.1 - 1.7e-107 359.6 0.0 1.9e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Tam41_Mmp37 PF09139.11 ORY95949.1 - 6.1e-08 32.5 1.2 9.6e-08 31.8 0.1 1.7 2 0 0 2 2 2 1 Phosphatidate cytidylyltransferase, mitochondrial DUF3408 PF11888.8 ORY95949.1 - 0.026 14.7 1.0 0.034 14.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) FNIP_M PF14637.6 ORY95950.1 - 4e-58 197.1 0.1 1e-57 195.8 0.1 1.7 1 1 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 ORY95950.1 - 6.5e-35 120.5 0.4 1.2e-34 119.6 0.4 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 ORY95950.1 - 2.1e-16 61.3 0.6 2.1e-16 61.3 0.6 3.5 3 1 2 5 5 5 1 Folliculin-interacting protein N-terminus FCH PF00611.23 ORY95951.1 - 6.1e-11 42.5 0.5 1.5e-10 41.2 0.5 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 ORY95951.1 - 1.3e-10 40.9 0.0 2.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY95951.1 - 1.1e-09 37.8 0.2 1.8e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY95951.1 - 2.9e-08 33.2 0.0 5.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 ORY95951.1 - 0.053 13.2 6.5 0.13 12.0 6.5 1.6 1 0 0 1 1 1 0 BAR domain of APPL family DUF1759 PF03564.15 ORY95951.1 - 0.22 11.5 1.5 0.45 10.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Hormone_1 PF00103.20 ORY95951.1 - 0.43 10.3 3.2 1 9.1 3.2 1.6 1 0 0 1 1 1 0 Somatotropin hormone family ANAPC4_WD40 PF12894.7 ORY95952.1 - 0.031 14.6 0.0 0.25 11.6 0.0 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FtsH_ext PF06480.15 ORY95952.1 - 0.075 13.4 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 FtsH Extracellular WD40 PF00400.32 ORY95952.1 - 0.091 13.7 0.3 14 6.8 0.4 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat MMR_HSR1 PF01926.23 ORY95953.1 - 1.5e-11 44.4 0.0 3.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY95953.1 - 2.4e-05 24.0 0.0 0.0011 18.5 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY95953.1 - 4.4e-05 23.4 0.0 0.00018 21.4 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 ORY95953.1 - 0.0021 17.6 0.0 0.42 10.1 0.0 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B MeaB PF03308.16 ORY95953.1 - 0.0071 15.3 0.3 0.063 12.2 0.0 2.3 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 ORY95953.1 - 0.032 14.4 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORY95953.1 - 0.05 13.7 0.1 14 5.7 0.0 2.7 1 1 1 2 2 2 0 Dynamin family EPSP_synthase PF00275.20 ORY95954.1 - 4.7e-127 424.1 0.1 7.2e-127 423.5 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ORY95954.1 - 6.4e-94 314.0 0.1 1.7e-93 312.6 0.1 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 ORY95954.1 - 2e-47 162.4 0.0 6.6e-47 160.7 0.0 2.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 ORY95954.1 - 6.7e-31 107.6 0.0 1.7e-30 106.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 ORY95954.1 - 2e-23 82.5 0.0 7.6e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ORY95954.1 - 3.1e-09 36.4 0.2 7.9e-09 35.1 0.2 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 ORY95954.1 - 1.7e-06 27.9 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 ORY95954.1 - 5.6e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_18 PF13238.6 ORY95954.1 - 0.0029 18.2 0.0 0.0066 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY95954.1 - 0.031 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY95954.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY95954.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain YlzJ PF14035.6 ORY95954.1 - 0.065 13.5 0.1 2.3 8.5 0.0 2.9 2 0 0 2 2 2 0 YlzJ-like protein PDEase_I PF00233.19 ORY95956.1 - 1.5e-73 247.5 0.0 3.8e-73 246.1 0.0 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 ORY95956.1 - 3.2e-05 24.0 0.0 0.00053 20.1 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain LAG1-DNAbind PF09271.11 ORY95957.1 - 3.3e-45 154.4 0.1 7.4e-45 153.3 0.1 1.6 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 ORY95957.1 - 5e-22 78.8 0.0 7.5e-18 65.2 0.0 3.0 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain Sugar_tr PF00083.24 ORY95959.1 - 2.4e-93 313.5 18.6 2.9e-93 313.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY95959.1 - 3.8e-26 91.8 26.7 1.8e-18 66.6 8.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY95959.1 - 0.0096 15.2 17.6 0.051 12.9 6.9 2.5 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ORY95959.1 - 0.013 14.0 7.1 0.0071 14.8 5.1 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.15 ORY95959.1 - 0.32 10.9 7.3 0.28 11.1 3.9 2.3 1 1 1 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 ORY95959.1 - 4.2 7.2 6.6 5 6.9 4.4 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper OmpH PF03938.14 ORY95960.1 - 0.0021 18.4 3.6 0.0021 18.4 3.6 5.8 2 1 3 6 6 6 1 Outer membrane protein (OmpH-like) FliT PF05400.13 ORY95960.1 - 0.015 16.1 5.9 0.015 16.1 5.9 5.9 3 2 4 7 7 7 0 Flagellar protein FliT DUF4200 PF13863.6 ORY95960.1 - 0.022 15.1 16.9 0.022 15.1 16.9 5.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4200) Abi_C PF14355.6 ORY95960.1 - 0.1 12.7 1.3 0.94 9.6 0.2 3.1 2 0 0 2 2 2 0 Abortive infection C-terminus SAWADEE PF16719.5 ORY95960.1 - 0.11 12.6 3.3 0.59 10.1 0.2 2.9 2 0 0 2 2 2 0 SAWADEE domain SNARE PF05739.19 ORY95960.1 - 1 9.4 4.7 0.91 9.6 1.2 2.4 1 1 1 2 2 2 0 SNARE domain DUF3584 PF12128.8 ORY95960.1 - 2.2 5.7 62.1 0.0071 13.9 46.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 ORY95960.1 - 8.1 5.0 50.1 0.78 8.3 2.8 3.8 2 1 1 3 3 3 0 AAA domain Sugar_tr PF00083.24 ORY95961.1 - 0.0044 16.0 0.1 0.0053 15.7 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PIG-U PF06728.13 ORY96119.1 - 3.8e-111 371.8 39.4 4.8e-111 371.5 39.4 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 ORY96119.1 - 0.0046 16.7 16.2 0.011 15.5 15.9 1.7 1 1 0 1 1 1 1 8TM Microsporidial transmembrane domain RPN6_N PF18055.1 ORY96120.1 - 1.3e-43 148.1 1.2 3.4e-43 146.7 0.5 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 ORY96120.1 - 2.3e-18 66.6 1.4 8.8e-18 64.8 0.1 2.5 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 ORY96120.1 - 8.6e-12 44.6 5.9 2.2e-11 43.3 1.9 3.1 3 0 0 3 3 3 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 ORY96120.1 - 0.0019 18.1 6.1 17 5.7 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.9 ORY96120.1 - 0.052 13.1 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 DDRGK domain TPR_MalT PF17874.1 ORY96120.1 - 0.054 12.9 4.5 0.062 12.7 1.7 2.4 2 2 0 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 ORY96120.1 - 0.59 11.1 5.2 2.4 9.2 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat F-actin_cap_A PF01267.17 ORY96121.1 - 2.5e-104 348.4 1.0 2.8e-104 348.3 1.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF1921 PF09081.10 ORY96121.1 - 0.047 13.9 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) Tcp11 PF05794.13 ORY96122.1 - 1.1e-83 281.9 12.5 1.1e-83 281.9 12.5 2.4 2 0 0 2 2 2 1 T-complex protein 11 DDHD PF02862.17 ORY96122.1 - 0.14 12.3 8.8 0.47 10.6 8.8 1.9 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 ORY96122.1 - 0.47 9.6 4.7 0.82 8.8 4.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 ORY96122.1 - 0.49 8.2 11.9 0.84 7.5 11.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 ORY96122.1 - 1.1 7.7 16.6 1.9 6.9 16.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Plasmodium_Vir PF05795.11 ORY96122.1 - 4.7 6.5 11.5 3 7.2 8.8 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.10 ORY96122.1 - 7.2 5.2 13.1 2.9 6.5 6.6 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup MMM1 PF10296.9 ORY96122.1 - 9.9 5.1 11.3 18 4.3 11.3 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 PfkB PF00294.24 ORY96123.1 - 4.3e-24 85.3 0.1 2.9e-23 82.6 0.1 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Pkinase PF00069.25 ORY96124.1 - 1.5e-58 198.3 0.0 2.6e-58 197.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96124.1 - 1e-35 123.3 0.0 1.7e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 ORY96124.1 - 1.5e-16 60.0 31.2 2.4e-08 33.7 11.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 ORY96124.1 - 2.3e-05 23.8 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 ORY96124.1 - 0.00055 20.6 2.0 0.0018 18.9 1.2 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain FAM199X PF15814.5 ORY96124.1 - 0.031 13.4 9.2 0.062 12.4 9.2 1.4 1 0 0 1 1 1 0 Protein family FAM199X PHD PF00628.29 ORY96124.1 - 4 7.4 27.8 1.2 9.1 9.4 2.7 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 ORY96124.1 - 9.8 6.4 19.0 0.54 10.4 6.5 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger ERG2_Sigma1R PF04622.12 ORY96125.1 - 4.5e-91 303.9 0.2 5.2e-91 303.6 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Herpes_teg_N PF04843.12 ORY96125.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region DUF4231 PF14015.6 ORY96125.1 - 0.16 12.4 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PMT PF02366.18 ORY96126.1 - 5.2e-41 140.8 12.7 8.9e-41 140.1 12.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 ORY96126.1 - 1.3e-22 80.5 5.6 1.3e-22 80.5 5.6 1.9 2 0 0 2 2 2 1 MIR domain PMT_4TMC PF16192.5 ORY96126.1 - 4.7e-11 42.6 1.6 4.7e-11 42.6 1.6 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 ORY96126.1 - 0.00037 20.8 2.5 0.00037 20.8 2.5 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SDA1 PF05285.12 ORY96127.1 - 1.2e-83 281.5 48.3 4.8e-83 279.5 38.6 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 ORY96127.1 - 1.4e-24 86.2 0.2 3.5e-24 84.9 0.2 1.8 1 0 0 1 1 1 1 NUC130/3NT domain WLM PF08325.10 ORY96128.1 - 3.6e-47 160.9 0.0 4.8e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 ORY96128.1 - 2.8e-07 29.7 12.3 0.00011 21.4 1.2 2.2 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Stc1 PF12898.7 ORY96128.1 - 0.064 13.8 4.0 5.5 7.6 0.4 2.4 1 1 1 2 2 2 0 Stc1 domain DUF45 PF01863.17 ORY96128.1 - 0.21 11.6 0.1 0.34 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Ephrin_rec_like PF07699.13 ORY96128.1 - 0.52 10.1 8.5 0.26 11.1 0.9 2.3 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-4CXXC_R1 PF10497.9 ORY96128.1 - 5.5 7.3 10.3 11 6.3 3.5 2.3 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 N2227 PF07942.12 ORY96129.1 - 6e-105 350.3 0.0 9.5e-105 349.7 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 ORY96129.1 - 0.0047 17.6 0.6 0.023 15.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Takusan PF04822.13 ORY96129.1 - 0.079 12.9 2.1 0.17 11.8 2.1 1.5 1 0 0 1 1 1 0 Takusan Actino_peptide PF14408.6 ORY96130.1 - 0.021 14.9 2.3 0.045 13.9 2.3 1.6 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes OPA3 PF07047.12 ORY96130.1 - 0.068 13.0 0.6 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) Lin-8 PF03353.15 ORY96130.1 - 6.2 6.3 15.2 4.5 6.7 10.1 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2729 PF10870.8 ORY96131.1 - 0.16 11.9 0.4 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) Diphthamide_syn PF01866.17 ORY96132.1 - 9.1e-105 350.4 1.0 2.4e-104 349.0 1.0 1.6 1 1 0 1 1 1 1 Putative diphthamide synthesis protein GPP34 PF05719.11 ORY96133.1 - 1.9e-61 207.6 0.0 2.4e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Fanconi_C PF02106.15 ORY96133.1 - 0.081 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia group C protein DUF4536 PF15055.6 ORY96134.1 - 1.1e-07 32.0 2.7 1.1e-07 32.0 1.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) DUF5516 PF17637.2 ORY96134.1 - 0.11 12.2 1.1 0.22 11.3 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Cut8 PF08559.10 ORY96135.1 - 1.4e-41 142.7 0.0 1.7e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Amidohydro_2 PF04909.14 ORY96136.1 - 1.6e-25 90.5 0.1 2.4e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Sporozoite_P67 PF05642.11 ORY96136.1 - 0.16 10.0 2.3 0.23 9.5 2.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_7 PF13176.6 ORY96137.1 - 0.019 15.0 0.3 0.064 13.3 0.3 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96137.1 - 0.019 15.0 0.7 0.065 13.4 0.7 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Atrophin-1 PF03154.15 ORY96137.1 - 2.5 6.3 11.4 3.4 5.8 11.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family Usp PF00582.26 ORY96138.1 - 2.7e-15 57.1 0.1 3.4e-14 53.5 0.0 2.6 2 2 0 2 2 2 1 Universal stress protein family zf-C3HC4 PF00097.25 ORY96140.1 - 6.4e-10 38.7 8.4 1.3e-09 37.8 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY96140.1 - 6.1e-09 36.1 10.3 1.1e-08 35.3 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY96140.1 - 2e-08 34.1 9.8 2.4e-08 33.9 7.9 2.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY96140.1 - 2.3e-08 33.7 10.1 3.9e-08 33.0 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY96140.1 - 3.9e-08 33.0 8.6 6.3e-08 32.3 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY96140.1 - 5e-08 32.8 8.0 9.5e-08 31.9 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 ORY96140.1 - 1.2e-06 28.5 2.8 1.7e-06 28.0 2.8 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 ORY96140.1 - 3.4e-06 27.1 8.1 6.4e-06 26.2 8.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY96140.1 - 7.2e-06 25.8 10.1 1.3e-05 24.9 10.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY96140.1 - 0.00064 20.0 10.6 0.0014 18.9 10.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY96140.1 - 0.003 17.6 5.7 0.0055 16.7 5.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY96140.1 - 0.02 14.5 10.1 0.037 13.7 10.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1244 PF06844.11 ORY96140.1 - 0.16 12.2 0.6 0.44 10.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-RING_6 PF14835.6 ORY96140.1 - 0.27 11.1 4.9 0.53 10.2 4.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.7 ORY96140.1 - 0.46 10.6 6.1 2.1 8.5 6.1 2.1 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 ORY96140.1 - 1.1 9.1 7.5 4.2 7.2 7.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 ORY96140.1 - 3.3 8.0 12.0 21 5.4 12.1 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Chromo PF00385.24 ORY96141.1 - 8.1e-11 41.7 1.1 1.6e-10 40.8 1.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 ORY96141.1 - 6.9e-07 29.3 0.1 3.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain adh_short_C2 PF13561.6 ORY96142.1 - 2.1e-52 178.0 0.3 2.9e-52 177.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY96142.1 - 7.9e-49 165.8 0.2 1.2e-48 165.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY96142.1 - 2.6e-08 34.0 0.1 4e-08 33.4 0.1 1.4 1 1 0 1 1 1 1 KR domain TFIIB PF00382.19 ORY96142.1 - 0.0094 16.0 1.2 0.11 12.6 0.0 2.7 3 0 0 3 3 3 1 Transcription factor TFIIB repeat Epimerase PF01370.21 ORY96142.1 - 0.047 13.2 0.0 0.082 12.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY96142.1 - 0.097 12.7 0.1 0.26 11.4 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.32 ORY96143.1 - 5.5e-49 163.1 22.5 4.6e-08 33.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96143.1 - 7.2e-10 39.0 2.8 0.19 12.0 0.0 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY96143.1 - 1.1e-06 28.7 0.2 2.8e-05 24.1 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY96143.1 - 8.5e-05 21.7 0.0 0.53 9.2 0.0 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY96143.1 - 0.0016 17.1 0.0 0.53 8.8 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 ORY96143.1 - 0.0081 14.9 8.9 0.1 11.2 0.3 5.0 4 2 2 6 6 6 1 Nucleoporin Nup120/160 NAR2 PF16974.5 ORY96143.1 - 0.072 12.5 0.1 11 5.4 0.0 2.8 2 1 0 2 2 2 0 High-affinity nitrate transporter accessory PD40 PF07676.12 ORY96143.1 - 0.091 12.7 0.9 33 4.6 0.1 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat M20_dimer PF07687.14 ORY96144.1 - 2.8e-08 33.7 0.1 1.2e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORY96144.1 - 1.4e-07 31.4 0.0 2.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Activator-TraM PF11657.8 ORY96144.1 - 0.019 14.8 0.3 0.039 13.8 0.3 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM F-box-like PF12937.7 ORY96146.1 - 2e-07 30.8 0.2 3.4e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 F-box-like TPR_9 PF13371.6 ORY96146.1 - 0.0032 17.6 1.6 0.0064 16.6 1.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.33 ORY96146.1 - 0.009 15.9 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPR_7 PF13176.6 ORY96146.1 - 0.046 13.8 0.9 0.29 11.3 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96146.1 - 0.046 13.8 6.0 0.98 9.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PSD5 PF07637.11 ORY96146.1 - 0.095 13.1 0.1 5.9 7.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1595) F-box-like PF12937.7 ORY96147.1 - 3.2e-06 26.9 0.4 7.7e-06 25.7 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY96147.1 - 0.0019 18.0 0.0 0.0048 16.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRA-CH PF01502.18 ORY96147.1 - 0.12 12.2 0.5 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase MAT1 PF06391.13 ORY96149.1 - 3.2e-52 177.3 21.1 4e-52 177.0 21.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 ORY96149.1 - 4.1e-20 71.4 6.9 8.3e-20 70.4 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY96149.1 - 1.6e-05 24.7 6.8 4.7e-05 23.2 7.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY96149.1 - 3.7e-05 23.6 7.7 0.0004 20.3 8.2 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY96149.1 - 6.1e-05 22.8 6.3 0.00015 21.6 6.3 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY96149.1 - 0.00015 22.0 7.0 0.00028 21.2 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY96149.1 - 0.00061 19.6 10.2 0.0023 17.7 10.5 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY96149.1 - 0.00084 19.1 4.3 0.035 13.9 1.4 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 ORY96149.1 - 0.0052 16.8 8.0 0.018 15.1 8.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY96149.1 - 0.073 12.9 10.3 2.2 8.2 10.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 GAGA PF09237.11 ORY96149.1 - 0.19 11.5 2.3 8 6.3 0.5 2.8 2 0 0 2 2 2 0 GAGA factor Thioredoxin_4 PF13462.6 ORY96149.1 - 1.5 8.9 0.0 1.5 8.9 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin zf-C3HC4_4 PF15227.6 ORY96149.1 - 2.4 8.4 9.2 9.2 6.5 9.1 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3797 PF12677.7 ORY96149.1 - 2.7 8.0 5.6 0.49 10.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DUF4407 PF14362.6 ORY96149.1 - 3 7.1 11.7 3.9 6.7 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WWE PF02825.20 ORY96150.1 - 0.024 15.2 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 WWE domain PPR_2 PF13041.6 ORY96151.1 - 1.3e-68 226.9 18.2 5.6e-10 39.3 0.0 13.9 6 5 9 15 15 15 12 PPR repeat family PPR PF01535.20 ORY96151.1 - 7.3e-54 176.3 8.9 0.00031 20.8 0.0 16.6 18 1 0 18 18 16 10 PPR repeat PPR_3 PF13812.6 ORY96151.1 - 2.5e-51 171.6 2.9 1.9e-11 43.8 0.1 9.6 5 2 3 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY96151.1 - 5.5e-39 133.7 2.4 4.1e-20 72.0 0.2 6.3 3 2 3 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY96151.1 - 1.7e-30 104.4 0.0 0.001 18.8 0.0 11.2 11 0 0 11 11 11 7 PPR repeat TPR_14 PF13428.6 ORY96151.1 - 3.8e-10 39.7 3.1 1.1 10.3 0.0 9.6 11 1 1 12 12 9 2 Tetratricopeptide repeat ECSIT PF06239.11 ORY96151.1 - 2.5e-06 26.8 3.1 1.4 8.0 0.0 6.2 4 1 1 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_19 PF14559.6 ORY96151.1 - 1.3e-05 25.6 0.0 0.53 10.8 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORY96151.1 - 7.2e-05 21.8 0.4 0.022 13.7 0.0 4.3 4 2 1 5 5 5 1 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 ORY96151.1 - 0.00014 21.7 0.2 0.22 11.4 0.0 5.5 4 2 1 5 5 5 1 Mitochondrial ATPase expression Clathrin PF00637.20 ORY96151.1 - 0.00015 21.7 5.3 0.099 12.5 0.9 5.4 5 2 0 5 5 5 1 Region in Clathrin and VPS TPR_16 PF13432.6 ORY96151.1 - 0.0013 19.3 1.6 4.5 8.0 0.0 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat AEP1 PF17049.5 ORY96151.1 - 0.0017 17.5 0.3 1.5 7.8 0.0 4.1 2 1 3 5 5 5 1 ATPase expression protein 1 TPR_12 PF13424.6 ORY96151.1 - 0.028 14.7 0.6 0.74 10.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY96151.1 - 0.075 13.3 5.1 2.1 8.7 0.0 5.3 6 2 2 8 8 8 0 Vacuolar sorting protein 39 domain 1 ANAPC3 PF12895.7 ORY96151.1 - 0.11 12.7 0.3 18 5.6 0.0 3.9 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 LSM PF01423.22 ORY96152.1 - 1.2e-20 73.0 0.0 1.3e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain AAA PF00004.29 ORY96153.1 - 8.8e-43 145.9 0.0 1.6e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY96153.1 - 9.1e-31 105.7 0.1 3.2e-30 103.9 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ORY96153.1 - 6.1e-22 77.5 2.8 6.1e-22 77.5 2.8 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ORY96153.1 - 3.9e-09 36.2 0.0 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY96153.1 - 1e-05 26.0 0.1 0.00091 19.6 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 ORY96153.1 - 1.4e-05 25.4 0.0 0.0071 16.7 0.0 3.5 3 0 0 3 3 3 1 RNA helicase RuvB_N PF05496.12 ORY96153.1 - 1.8e-05 24.5 0.0 5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY96153.1 - 2.2e-05 24.5 0.0 0.00011 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY96153.1 - 7.9e-05 22.9 0.1 0.0091 16.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY96153.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 ORY96153.1 - 0.00015 21.0 0.0 0.0004 19.6 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 ORY96153.1 - 0.00021 21.3 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORY96153.1 - 0.00031 20.1 0.0 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 ORY96153.1 - 0.00042 20.9 0.5 0.0026 18.3 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY96153.1 - 0.002 17.9 1.2 0.014 15.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 ORY96153.1 - 0.0034 17.6 0.0 0.0087 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY96153.1 - 0.0062 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF3543 PF12063.8 ORY96153.1 - 0.0066 15.9 0.2 0.01 15.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) AAA_17 PF13207.6 ORY96153.1 - 0.0089 16.5 0.1 0.052 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORY96153.1 - 0.016 14.8 0.1 0.79 9.3 0.1 2.4 1 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY96153.1 - 0.021 14.8 1.2 1.9 8.3 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 ORY96153.1 - 0.031 13.7 0.0 0.088 12.2 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORY96153.1 - 0.038 13.5 0.2 0.23 11.0 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 ORY96153.1 - 0.047 13.6 0.0 0.54 10.2 0.0 2.1 1 1 1 2 2 2 0 NACHT domain HEPN_AbiA_CTD PF18732.1 ORY96153.1 - 0.053 13.4 2.9 0.12 12.3 2.9 1.5 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain Parvo_NS1 PF01057.17 ORY96153.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 ORY96153.1 - 0.064 12.6 0.0 6.6 6.0 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 ORY96153.1 - 0.08 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 ORY96153.1 - 0.086 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Torsin Bac_DnaA PF00308.18 ORY96153.1 - 0.1 12.4 0.1 1.5 8.6 0.0 2.7 2 2 0 2 2 2 0 Bacterial dnaA protein CPT PF07931.12 ORY96153.1 - 0.11 12.3 0.0 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 ORY96153.1 - 0.14 11.9 0.0 0.46 10.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain EF-1_beta_acid PF10587.9 ORY96153.1 - 0.23 11.9 2.9 0.53 10.8 0.5 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region TPR_2 PF07719.17 ORY96153.1 - 0.46 10.7 2.3 0.5 10.6 0.3 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat F_bP_aldolase PF01116.20 ORY96155.1 - 1e-93 313.9 0.0 1.1e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Alpha_L_fucos PF01120.17 ORY96156.1 - 1.7e-81 274.4 4.2 3e-81 273.6 4.2 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase Lipase_3 PF01764.25 ORY96156.1 - 2.2e-12 47.0 0.0 4.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Fucosidase_C PF16757.5 ORY96156.1 - 5.3e-06 26.9 0.0 1.8e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 ORY96156.1 - 0.0022 18.1 0.0 0.0076 16.4 0.0 2.0 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Macoilin PF09726.9 ORY96156.1 - 3.8 5.9 10.2 5.7 5.4 10.2 1.2 1 0 0 1 1 1 0 Macoilin family Spem1 PF15670.5 ORY96156.1 - 4.5 6.8 7.2 13 5.3 7.2 1.8 1 0 0 1 1 1 0 Spermatid maturation protein 1 Glyco_transf_22 PF03901.17 ORY96158.1 - 1.4e-37 129.9 27.2 2e-37 129.4 27.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glutaredoxin PF00462.24 ORY96158.1 - 7.6e-11 42.1 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 ORY96158.1 - 0.03 14.7 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Arrestin_C PF02752.22 ORY96159.1 - 3.4e-10 40.5 7.4 5.4e-09 36.6 0.8 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY96159.1 - 1.4e-09 38.2 0.0 8.1e-08 32.4 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Nucleo_P87 PF07267.11 ORY96159.1 - 0.075 11.9 0.1 0.075 11.9 0.1 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus capsid protein P87 PX PF00787.24 ORY96160.1 - 6.1e-19 68.1 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 PX domain DUF4606 PF15379.6 ORY96160.1 - 0.085 13.1 0.8 0.51 10.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) POX PF07526.11 ORY96160.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.3 1 1 1 2 2 2 0 Associated with HOX CDC37_N PF03234.14 ORY96161.1 - 2.4e-34 119.0 11.4 2.4e-34 119.0 11.4 3.6 2 2 2 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 ORY96161.1 - 3.5e-33 114.0 0.8 3.5e-33 114.0 0.8 2.5 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 ORY96161.1 - 4.7e-16 58.7 0.3 4.7e-16 58.7 0.3 3.9 3 2 1 4 4 4 1 Cdc37 C terminal domain Striatin PF08232.12 ORY96161.1 - 0.0061 17.2 12.1 0.0061 17.2 12.1 2.5 1 1 1 2 2 2 1 Striatin family TFIIA PF03153.13 ORY96161.1 - 2.1 8.2 31.7 0.22 11.5 26.7 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SbcD_C PF12320.8 ORY96161.1 - 4.3 7.7 22.5 0.034 14.4 4.5 3.8 4 0 0 4 4 4 0 Type 5 capsule protein repressor C-terminal domain DUF445 PF04286.12 ORY96161.1 - 6.1 6.5 17.6 3.7 7.3 12.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF445) Usp PF00582.26 ORY96161.1 - 8.3 6.9 9.2 6.8 7.2 0.5 2.8 2 1 0 2 2 2 0 Universal stress protein family Asp PF00026.23 ORY96162.1 - 7.3e-15 55.2 0.0 2.7e-13 50.1 0.0 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY96162.1 - 0.00035 20.4 0.0 0.079 12.7 0.0 2.8 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Ferredoxin_N PF16947.5 ORY96162.1 - 0.12 12.6 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding gag-asp_proteas PF13975.6 ORY96162.1 - 0.13 12.9 0.0 24 5.6 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Cellulase PF00150.18 ORY96163.1 - 9e-16 58.1 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 ORY96163.1 - 0.018 14.4 0.0 4.9 6.4 0.1 2.2 1 1 1 2 2 2 0 Beta-galactosidase Pkinase PF00069.25 ORY96164.1 - 8.2e-51 172.9 0.0 1.1e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96164.1 - 1.3e-30 106.6 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY96164.1 - 3.3e-06 26.6 0.0 1.3e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 ORY96164.1 - 0.00094 18.3 0.1 0.0014 17.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY96164.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY96164.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Na_H_Exchanger PF00999.21 ORY96165.1 - 3.6e-58 197.2 49.2 4.6e-58 196.8 49.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 ORY96166.1 - 0.017 15.6 0.1 0.033 14.7 0.1 1.5 1 0 0 1 1 1 0 Universal stress protein family Pkinase PF00069.25 ORY96167.1 - 2.2e-71 240.4 0.0 2.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96167.1 - 5.8e-35 120.8 0.0 7.9e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY96167.1 - 0.0003 20.2 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY96167.1 - 0.06 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain WGR PF05406.15 ORY96167.1 - 0.12 12.5 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 WGR domain Alg6_Alg8 PF03155.15 ORY96168.1 - 1.3e-161 538.9 28.3 1.5e-161 538.7 28.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Sugar_tr PF00083.24 ORY96169.1 - 1.3e-99 334.1 24.7 3.5e-51 174.5 5.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY96169.1 - 1.2e-25 90.2 42.2 6.9e-23 81.1 20.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Glug PF07581.12 ORY96169.1 - 0.17 12.3 1.9 0.67 10.5 1.9 2.0 1 0 0 1 1 1 0 The GLUG motif p450 PF00067.22 ORY96170.1 - 4.7e-147 490.5 0.0 5.8e-77 259.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 NAC PF01849.18 ORY96171.1 - 6.7e-24 83.6 0.0 1.6e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 NAC domain DUF3602 PF12223.8 ORY96171.1 - 0.016 15.8 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) DHHC PF01529.20 ORY96172.1 - 4e-31 107.9 20.3 4e-31 107.9 20.3 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 ORY96172.1 - 4.2e-13 49.7 0.4 3.1e-11 43.7 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY96172.1 - 3.2e-12 46.3 3.3 0.0002 21.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY96172.1 - 6.8e-11 42.2 1.6 6.9e-06 26.2 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY96172.1 - 7.1e-10 39.2 0.8 6.8e-05 23.3 0.0 3.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY96172.1 - 1.6e-09 37.2 0.4 0.037 14.6 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Leukocidin PF07968.12 ORY96172.1 - 0.029 14.3 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Leukocidin/Hemolysin toxin family Ank_2 PF12796.7 ORY96173.1 - 4.3e-09 36.8 0.0 6.4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY96173.1 - 2e-06 28.0 2.1 0.0001 22.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY96173.1 - 2e-06 28.0 0.2 6.7e-06 26.3 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY96173.1 - 5.7e-06 26.8 1.9 0.0086 16.6 0.2 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY96173.1 - 1.4e-05 25.1 0.2 0.0036 17.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Inositol_P PF00459.25 ORY96174.1 - 2.5e-71 240.4 0.3 2.9e-71 240.2 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family V-SNARE_C PF12352.8 ORY96175.1 - 2e-17 63.2 4.6 3.2e-17 62.6 4.2 1.5 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus YqjK PF13997.6 ORY96175.1 - 0.044 14.0 3.5 0.18 12.1 0.0 2.6 2 1 1 3 3 3 0 YqjK-like protein Sec20 PF03908.13 ORY96175.1 - 0.073 13.0 0.5 0.13 12.2 0.3 1.5 1 1 1 2 2 2 0 Sec20 ArnB_C PF18677.1 ORY96175.1 - 0.8 9.9 5.1 12 6.1 5.1 2.4 1 1 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Proteasome PF00227.26 ORY96176.1 - 3e-49 167.1 0.2 3.6e-49 166.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit HECT PF00632.25 ORY96177.1 - 1.7e-97 326.7 0.0 2.4e-97 326.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORY96177.1 - 2.3e-36 123.5 22.4 8.5e-13 48.2 2.6 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 ORY96177.1 - 7.1e-21 74.4 0.4 1.8e-20 73.1 0.4 1.7 1 0 0 1 1 1 1 C2 domain Tube PF17212.3 ORY96177.1 - 0.087 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Tail tubular protein TFIIA PF03153.13 ORY96177.1 - 1.8 8.5 14.0 2.6 7.9 14.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Porin_3 PF01459.22 ORY96178.1 - 4.2e-73 246.1 0.9 4.8e-73 245.9 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin CPSase_L_D2 PF02786.17 ORY96179.1 - 2e-79 266.0 0.5 3.7e-79 265.1 0.5 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ORY96179.1 - 6.5e-72 241.5 0.0 1.1e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ORY96179.1 - 5.2e-38 130.0 0.1 1.3e-37 128.7 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY96179.1 - 1.9e-31 108.4 0.0 7e-31 106.5 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ORY96179.1 - 1.4e-30 106.8 0.0 2.6e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ORY96179.1 - 3.5e-16 58.8 2.4 4.7e-16 58.4 0.5 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY96179.1 - 2.3e-10 40.4 0.0 4.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY96179.1 - 2.7e-08 33.6 0.1 5.7e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 ORY96179.1 - 1.6e-05 25.6 1.0 0.059 14.1 0.1 3.4 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 ORY96179.1 - 3.6e-05 23.9 0.0 8.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY96179.1 - 4.9e-05 23.1 0.3 0.47 10.3 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_4 PF13535.6 ORY96179.1 - 0.00016 21.3 0.1 0.0039 16.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 ORY96179.1 - 0.0086 15.4 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 ORY96179.1 - 0.0087 15.3 0.1 0.18 11.0 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3182 PF11379.8 ORY96179.1 - 0.026 13.5 0.0 0.064 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3182) ATPgrasp_Ter PF15632.6 ORY96179.1 - 0.18 11.6 2.1 0.53 10.0 0.3 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF2118 PF09891.9 ORY96179.1 - 0.23 11.4 0.9 0.77 9.7 0.2 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) KAR9 PF08580.10 ORY96180.1 - 1.5e-14 53.5 50.2 4.1e-11 42.2 2.3 4.1 1 1 0 2 2 2 2 Yeast cortical protein KAR9 GAS2 PF02187.17 ORY96180.1 - 5.8e-06 26.3 0.2 0.00018 21.5 0.2 3.0 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain IF-2B PF01008.17 ORY96181.1 - 1.8e-62 211.2 0.0 2e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family EarP PF10093.9 ORY96181.1 - 0.049 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Tymo_45kd_70kd PF03251.13 ORY96181.1 - 0.057 12.4 0.1 0.084 11.8 0.1 1.1 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein DeoRC PF00455.22 ORY96181.1 - 0.077 12.9 0.0 0.98 9.3 0.0 2.3 2 1 1 3 3 3 0 DeoR C terminal sensor domain Methyltransf_25 PF13649.6 ORY96182.1 - 4.1e-15 56.2 0.0 9.2e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96182.1 - 4e-13 49.8 0.0 7.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96182.1 - 1.7e-11 44.2 0.0 3.1e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96182.1 - 4.7e-08 33.0 0.0 6.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY96182.1 - 1.1e-07 31.5 0.0 4.2e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY96182.1 - 1.4e-06 27.9 0.0 5.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 ORY96182.1 - 0.00047 20.9 0.0 0.00095 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY96182.1 - 0.0019 17.5 0.1 0.0061 15.9 0.0 1.9 2 1 0 2 2 2 1 O-methyltransferase domain PCMT PF01135.19 ORY96182.1 - 0.0028 17.4 0.0 0.0072 16.1 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 ORY96182.1 - 0.0052 16.9 0.1 0.0064 16.6 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 ORY96182.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 ORY96182.1 - 0.033 13.1 0.1 0.043 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 ORY96182.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 ORY96182.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.20 ORY96182.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glyco_hydro_88 PF07470.13 ORY96183.1 - 3.4e-92 309.1 3.5 3.9e-92 309.0 3.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 ORY96183.1 - 0.00014 20.5 0.3 0.00022 19.9 0.3 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 ORY96184.1 - 7.4e-34 117.2 25.4 4.4e-33 114.7 25.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 ORY96185.1 - 1e-33 116.7 29.0 1.5e-33 116.2 29.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Neugrin PF06413.11 ORY96186.1 - 1.1e-12 48.5 0.4 1.4e-12 48.2 0.4 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 ORY96186.1 - 4.2e-06 27.0 1.5 8.1e-06 26.1 1.5 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Sigma70_r4 PF04545.16 ORY96186.1 - 0.00028 20.4 0.3 0.002 17.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 ORY96186.1 - 0.0036 17.0 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain UPF0240 PF06784.11 ORY96186.1 - 0.014 15.4 0.1 0.031 14.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0240) HTH_32 PF13565.6 ORY96186.1 - 0.023 15.3 0.1 0.023 15.3 0.1 1.7 2 0 0 2 2 2 0 Homeodomain-like domain DUF134 PF02001.16 ORY96186.1 - 0.037 14.6 0.1 0.056 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF134 DUF4244 PF14029.6 ORY96187.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) SipA PF09052.10 ORY96188.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 SipA N-terminal domain ST7 PF04184.12 ORY96189.1 - 0.16 10.4 0.0 0.16 10.4 0.0 1.0 1 0 0 1 1 1 0 ST7 protein HSA PF07529.13 ORY96190.1 - 4.4e-14 52.6 1.4 4.4e-14 52.6 1.4 5.8 7 0 0 7 7 7 1 HSA Myb_DNA-bind_6 PF13921.6 ORY96190.1 - 4.9e-10 39.5 5.8 6.8e-10 39.0 0.2 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY96190.1 - 8e-05 22.8 0.2 0.0002 21.5 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain F5_F8_type_C PF00754.25 ORY96192.1 - 0.0015 18.7 0.3 0.0035 17.5 0.3 1.6 1 0 0 1 1 1 1 F5/8 type C domain CBM_6 PF03422.15 ORY96192.1 - 0.013 15.8 0.2 0.028 14.7 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) Ribosomal_L6 PF00347.23 ORY96193.1 - 1.3e-20 73.8 0.0 1.6e-10 41.5 0.0 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 Methyltransf_32 PF13679.6 ORY96194.1 - 2.1e-27 96.1 0.1 3.8e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96194.1 - 6.2e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96194.1 - 0.00027 20.8 0.0 0.0006 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY96194.1 - 0.00055 20.6 0.1 0.0019 18.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96194.1 - 0.0028 18.4 0.0 0.0063 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96194.1 - 0.0033 18.0 0.0 0.0095 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY96194.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 ORY96194.1 - 0.16 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ELP6 PF09807.9 ORY96195.1 - 1.8e-51 175.0 0.1 2.2e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 ORY96195.1 - 3.1e-06 26.9 0.5 4.8e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 Elongator subunit Iki1 ATPase PF06745.13 ORY96195.1 - 0.0004 19.8 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 KaiC DUF835 PF05763.12 ORY96195.1 - 0.034 13.9 0.0 0.16 11.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF835) Bromodomain PF00439.25 ORY96196.1 - 1.3e-44 150.1 3.1 2.3e-22 78.9 0.6 2.5 2 0 0 2 2 2 2 Bromodomain Ank_2 PF12796.7 ORY96196.1 - 2.2e-08 34.6 0.0 4.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY96196.1 - 2.6e-08 33.9 0.3 0.00081 19.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY96196.1 - 2.4e-07 30.5 0.0 0.0084 16.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY96196.1 - 5e-07 29.9 0.3 0.00022 21.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY96196.1 - 5.4e-05 23.7 0.1 0.00033 21.2 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AT_hook PF02178.19 ORY96196.1 - 0.36 10.9 6.7 0.12 12.4 1.8 2.8 2 0 0 2 2 2 0 AT hook motif ThrE PF06738.12 ORY96197.1 - 7.7e-38 130.2 21.3 2.3e-36 125.4 6.2 2.3 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY96197.1 - 6.7e-07 29.5 29.3 0.00012 22.2 8.3 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE MotA_ExbB PF01618.16 ORY96197.1 - 2.9 7.7 8.2 0.13 12.0 1.0 2.2 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Zn_clus PF00172.18 ORY96198.1 - 7.9e-09 35.5 12.5 1.6e-08 34.6 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFRD PF05004.13 ORY96198.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) RHH_1 PF01402.21 ORY96198.1 - 0.11 12.5 0.0 9.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family AIG1 PF04548.16 ORY96199.1 - 1.9e-08 33.9 0.0 2.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 ORY96199.1 - 5.9e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY96199.1 - 9.7e-05 22.4 0.0 0.00016 21.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY96199.1 - 0.00089 19.2 0.9 0.0057 16.6 0.9 2.0 1 1 0 1 1 1 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 ORY96199.1 - 0.0048 16.3 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 ORY96199.1 - 0.011 15.8 0.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 ORY96200.1 - 1.7e-43 148.2 0.0 4.1e-43 147.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY96200.1 - 9.9e-13 47.7 1.2 2e-12 46.7 0.1 2.1 2 0 0 2 2 2 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORY96200.1 - 1.6e-08 34.4 1.0 3.9e-08 33.1 1.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 ORY96200.1 - 4.2e-07 30.2 0.0 9.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORY96200.1 - 1.7e-06 28.1 0.0 1.3e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY96200.1 - 1.9e-06 28.4 0.1 6.5e-05 23.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORY96200.1 - 3e-05 24.3 0.0 0.0049 17.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY96200.1 - 8.9e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ORY96200.1 - 0.0012 18.2 0.0 0.0026 17.0 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ORY96200.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY96200.1 - 0.0023 17.7 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORY96200.1 - 0.003 18.1 0.1 0.021 15.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 ORY96200.1 - 0.0066 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY96200.1 - 0.0082 15.6 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ORY96200.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY96200.1 - 0.012 15.1 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 ORY96200.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 ORY96200.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2072 PF09845.9 ORY96200.1 - 0.018 15.3 0.3 0.041 14.1 0.3 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Sigma54_activat PF00158.26 ORY96200.1 - 0.025 14.3 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 ORY96200.1 - 0.027 13.7 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY96200.1 - 0.029 14.1 0.0 0.093 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY96200.1 - 0.034 14.2 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY96200.1 - 0.035 13.6 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RILP PF11461.8 ORY96200.1 - 0.04 14.2 1.2 0.089 13.0 1.2 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein RNA_helicase PF00910.22 ORY96200.1 - 0.048 14.0 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 ORY96200.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 ORY96200.1 - 0.061 13.7 0.1 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY96200.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY96200.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 ORY96200.1 - 0.13 12.1 0.2 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY96200.1 - 0.13 12.8 0.1 0.76 10.3 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Tim17 PF02466.19 ORY96201.1 - 0.0034 17.7 2.8 0.018 15.4 2.7 2.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF533 PF04391.12 ORY96201.1 - 0.026 14.1 0.1 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) TBCC_N PF16752.5 ORY96201.1 - 0.038 14.4 0.3 0.061 13.8 0.3 1.3 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain DUF4635 PF15466.6 ORY96201.1 - 0.14 11.7 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) PAP_central PF04928.17 ORY96202.1 - 2.6e-111 370.6 0.0 3.5e-111 370.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY96202.1 - 4e-42 143.8 0.0 6.5e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY96202.1 - 9.5e-10 38.6 0.0 2.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 ORY96202.1 - 0.027 14.7 0.0 0.088 13.0 0.0 1.8 1 1 0 1 1 1 0 DNA polymerase beta palm Polbeta PF18765.1 ORY96202.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase HetR_C PF18460.1 ORY96202.1 - 0.18 11.8 0.1 16 5.5 0.0 3.5 4 0 0 4 4 4 0 Heterocyst differentiation regulator C-terminal Hood domain Sel1 PF08238.12 ORY96203.1 - 6.1e-22 77.6 18.4 1.5e-06 28.7 0.0 6.3 6 0 0 6 6 6 5 Sel1 repeat Methyltransf_33 PF10017.9 ORY96204.1 - 3.6e-86 289.1 0.0 4.9e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 ORY96204.1 - 9.2e-28 97.5 6.4 1.1e-13 51.3 0.5 2.4 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 ORY96204.1 - 3.9e-08 33.8 3.0 1e-07 32.5 2.6 2.1 1 1 0 1 1 1 1 DinB superfamily DUF1566 PF07603.11 ORY96204.1 - 0.0058 17.0 1.7 0.016 15.6 1.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) Mitofilin PF09731.9 ORY96205.1 - 1.2e-90 305.2 35.2 4.4e-76 257.1 33.6 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein APG6_N PF17675.1 ORY96205.1 - 0.0012 19.3 14.1 0.0012 19.3 14.1 3.0 1 1 1 2 2 2 1 Apg6 coiled-coil region Sec34 PF04136.15 ORY96205.1 - 0.026 14.4 5.2 0.069 13.0 4.7 2.0 1 1 0 1 1 1 0 Sec34-like family YojJ PF10372.9 ORY96205.1 - 0.14 12.3 0.6 1.6 8.9 0.2 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus MCD_N PF17408.2 ORY96205.1 - 0.32 11.2 3.5 0.45 10.7 0.8 2.7 2 1 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DUF5486 PF17588.2 ORY96205.1 - 0.34 10.8 1.4 0.81 9.6 0.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Leu_zip PF15294.6 ORY96205.1 - 1.5 8.2 20.5 0.23 10.9 15.1 2.2 2 1 1 3 3 3 0 Leucine zipper YlqD PF11068.8 ORY96205.1 - 5.2 7.5 21.7 2.6 8.4 7.5 3.3 1 1 2 3 3 3 0 YlqD protein GTP_EFTU PF00009.27 ORY96206.1 - 1.8e-53 181.0 0.0 2.9e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ORY96206.1 - 2.2e-49 166.1 1.1 5.1e-49 164.9 1.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ORY96206.1 - 3.8e-22 78.1 0.2 8.1e-22 77.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY96206.1 - 6.6e-11 42.4 0.1 2e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY96206.1 - 9.9e-08 31.9 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ORY96206.1 - 2e-05 24.6 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 ORY96206.1 - 2.9e-05 24.0 0.0 7.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 ORY96206.1 - 5.5e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORY96206.1 - 0.00041 19.8 0.1 0.00094 18.7 0.1 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 ORY96206.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DPM2 PF07297.12 ORY96208.1 - 2.4e-30 104.6 1.4 2.9e-30 104.4 1.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 ORY96208.1 - 0.00071 19.5 0.4 0.00077 19.4 0.4 1.1 1 0 0 1 1 1 1 PIG-P O-ag_pol_Wzy PF14296.6 ORY96208.1 - 0.0046 15.7 0.1 0.0051 15.5 0.1 1.0 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy Phage_holin_3_6 PF07332.11 ORY96208.1 - 0.0052 16.8 0.0 0.0055 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III MBOAT PF03062.19 ORY96209.1 - 4.6e-38 131.5 12.8 1.8e-37 129.5 12.8 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SCAMP PF04144.13 ORY96210.1 - 1.3e-48 165.6 14.5 1.6e-48 165.3 14.5 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 ORY96210.1 - 0.086 12.3 1.2 0.16 11.4 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) C2 PF00168.30 ORY96212.1 - 1.2e-85 282.4 7.9 7.6e-20 71.1 0.2 6.4 6 0 0 6 6 6 6 C2 domain SMP_LBD PF17047.5 ORY96212.1 - 0.00028 20.4 0.0 0.0087 15.5 0.0 2.3 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain PHD PF00628.29 ORY96213.1 - 1.2e-06 28.3 9.4 2.3e-06 27.4 9.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY96213.1 - 0.016 14.8 9.1 0.025 14.1 9.1 1.3 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 ORY96213.1 - 0.072 13.1 5.1 0.15 12.1 5.1 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger Polysacc_deac_1 PF01522.21 ORY96214.1 - 3.1e-22 78.8 0.0 6.2e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DHDPS PF00701.22 ORY96214.1 - 0.0015 17.3 0.0 0.2 10.4 0.0 2.2 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family SecY PF00344.20 ORY96215.1 - 6.9e-68 229.1 13.2 9.2e-68 228.7 13.2 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORY96215.1 - 1.3e-17 63.4 0.4 3.2e-17 62.1 0.4 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p DUF4602 PF15375.6 ORY96216.1 - 2.5e-05 24.6 26.7 0.00022 21.6 26.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) p450 PF00067.22 ORY96217.1 - 9.2e-35 120.3 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM150 PF15129.6 ORY96218.1 - 2.5 8.3 4.9 0.51 10.5 0.6 2.0 2 1 0 2 2 2 0 FAM150 family AAA_2 PF07724.14 ORY96219.1 - 3.9e-55 186.6 0.1 7.3e-52 175.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORY96219.1 - 1.7e-34 117.9 1.2 1.7e-34 117.9 1.2 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 ORY96219.1 - 1.2e-24 86.2 2.3 2.1e-24 85.4 0.2 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ORY96219.1 - 1e-22 81.0 0.1 1.2e-11 45.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY96219.1 - 1.4e-16 60.7 0.2 3.8e-10 39.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY96219.1 - 6.2e-11 43.0 1.5 9.4e-05 22.9 0.2 4.5 3 1 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 ORY96219.1 - 8.1e-11 41.9 0.4 1.9e-06 27.7 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ORY96219.1 - 1.4e-08 35.1 3.1 0.012 15.9 0.0 4.5 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 ORY96219.1 - 4.5e-07 29.8 0.0 0.017 14.8 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 ORY96219.1 - 7.9e-07 28.7 0.0 0.0012 18.3 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 ORY96219.1 - 8.8e-07 29.0 0.2 0.018 15.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 ORY96219.1 - 1.9e-05 24.2 0.0 0.042 13.4 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORY96219.1 - 6.3e-05 22.5 0.0 0.6 9.5 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 ORY96219.1 - 8.7e-05 22.5 2.0 1.9 8.4 1.0 4.0 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ORY96219.1 - 0.00012 22.5 0.1 0.82 10.1 0.0 3.4 4 0 0 4 4 3 2 RNA helicase RuvB_N PF05496.12 ORY96219.1 - 0.00016 21.5 1.8 1.8 8.3 0.0 4.1 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORY96219.1 - 0.00021 21.8 0.8 1.4 9.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 ORY96219.1 - 0.00022 21.0 0.0 0.084 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ORY96219.1 - 0.00026 21.2 0.0 0.7 10.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 ORY96219.1 - 0.00062 19.8 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORY96219.1 - 0.00074 19.5 0.2 0.29 11.0 0.0 3.2 4 0 0 4 4 3 1 NACHT domain ABC_tran PF00005.27 ORY96219.1 - 0.00083 19.9 0.6 0.18 12.3 0.0 3.2 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.15 ORY96219.1 - 0.0027 17.8 0.1 5.9 6.8 0.0 3.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 ORY96219.1 - 0.0035 17.2 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 ORY96219.1 - 0.012 15.4 0.0 0.96 9.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 ORY96219.1 - 0.014 15.6 0.9 15 5.8 0.0 4.1 4 0 0 4 4 3 0 AAA domain Bac_DnaA PF00308.18 ORY96219.1 - 0.015 15.2 0.0 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_33 PF13671.6 ORY96219.1 - 0.018 15.2 0.0 12 6.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 ORY96219.1 - 0.024 14.3 0.0 2 8.0 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.6 ORY96219.1 - 0.039 13.7 0.0 17 5.1 0.0 3.5 4 0 0 4 4 3 0 DNA polymerase III, delta subunit AAA_30 PF13604.6 ORY96219.1 - 0.07 12.8 3.3 3.3 7.4 0.1 3.6 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 ORY96219.1 - 0.071 12.9 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein VGPC1_C PF16799.5 ORY96219.1 - 0.085 12.8 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 AAA_23 PF13476.6 ORY96219.1 - 0.13 12.7 10.3 1.5 9.3 1.6 3.6 3 1 0 3 3 3 0 AAA domain Prefoldin PF02996.17 ORY96219.1 - 0.94 9.4 4.2 0.52 10.2 0.4 2.6 3 0 0 3 3 3 0 Prefoldin subunit TCO89 PF10452.9 ORY96220.1 - 2e-11 43.6 1.4 2e-11 43.6 1.4 2.6 1 1 2 3 3 3 1 TORC1 subunit TCO89 WD40 PF00400.32 ORY96221.1 - 8.1e-09 36.0 6.7 0.00098 19.9 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96221.1 - 0.00035 20.8 0.0 1.1 9.6 0.0 4.2 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_25 PF13649.6 ORY96222.1 - 1.5e-16 60.9 0.0 2.6e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96222.1 - 3.2e-14 53.3 0.0 5.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96222.1 - 4.9e-12 46.0 0.0 1.2e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96222.1 - 6e-10 39.1 0.0 2e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96222.1 - 2e-06 28.5 0.0 5.5e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY96222.1 - 9.6e-05 21.8 0.0 0.0003 20.2 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORY96222.1 - 0.00036 20.4 0.0 0.00072 19.5 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 ORY96222.1 - 0.001 18.5 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 ORY96222.1 - 0.0019 16.9 0.0 0.0077 14.8 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase LRR_9 PF14580.6 ORY96223.1 - 8e-07 28.7 0.2 1.4e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 ORY96223.1 - 2.1e-06 28.3 0.2 0.0008 20.0 0.1 3.5 3 1 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 ORY96223.1 - 9.3e-05 22.7 2.3 0.00011 22.5 0.7 1.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 ORY96223.1 - 0.00041 20.1 0.0 0.00096 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Tap-RNA_bind PF09162.10 ORY96223.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Tap, RNA-binding LRR_8 PF13855.6 ORY96223.1 - 0.06 13.1 7.2 0.067 13.0 4.5 2.3 2 1 0 2 2 2 0 Leucine rich repeat Ribosomal_S11 PF00411.19 ORY96223.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 OrfB_Zn_ribbon PF07282.11 ORY96225.1 - 2.8e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY96226.1 - 0.003 17.5 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PAP2_C PF14360.6 ORY96227.1 - 7.6e-10 39.2 9.4 7.6e-10 39.2 9.4 2.9 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SPC25 PF06703.11 ORY96227.1 - 0.51 10.1 2.7 1.1 9.0 2.7 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sec23_trunk PF04811.15 ORY96228.1 - 3.4e-58 197.1 0.0 5.6e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY96228.1 - 3.8e-25 87.7 0.1 9.8e-25 86.4 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY96228.1 - 2.1e-19 70.0 0.2 6.8e-18 65.2 0.1 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY96228.1 - 1.1e-14 54.2 5.4 2.1e-14 53.2 5.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY96228.1 - 5.8e-10 38.9 0.0 3.8e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Gelsolin repeat Cytomega_gL PF01801.16 ORY96229.1 - 0.099 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L TFIIA PF03153.13 ORY96229.1 - 0.33 10.9 24.1 0.44 10.5 24.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gastrin PF00918.17 ORY96229.1 - 0.58 11.1 12.3 1.9 9.4 2.8 3.4 2 1 1 3 3 3 0 Gastrin/cholecystokinin family AUX_IAA PF02309.16 ORY96229.1 - 0.64 9.8 5.9 0.99 9.2 5.8 1.4 1 1 0 1 1 1 0 AUX/IAA family Exonuc_VII_L PF02601.15 ORY96229.1 - 2.3 7.7 9.4 4 6.9 9.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit WW PF00397.26 ORY96230.1 - 1.8e-13 50.3 1.2 1.8e-13 50.3 1.2 1.9 2 0 0 2 2 2 1 WW domain TFIIA PF03153.13 ORY96230.1 - 0.00011 22.4 5.8 0.00016 21.8 5.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3824 PF12868.7 ORY96230.1 - 0.0044 17.7 1.2 0.0044 17.7 1.2 3.4 1 1 2 3 3 3 1 Domain of unknwon function (DUF3824) LIM PF00412.22 ORY96232.1 - 1.2e-12 47.9 4.0 1.2e-12 47.9 4.0 2.3 2 0 0 2 2 2 1 LIM domain LIM PF00412.22 ORY96233.1 - 1.4e-26 92.5 21.1 1.1e-11 44.8 5.8 3.1 3 0 0 3 3 3 3 LIM domain DZR PF12773.7 ORY96233.1 - 0.14 12.2 21.4 5.8 7.0 5.0 3.6 2 2 0 2 2 2 0 Double zinc ribbon Arb1 PF09692.10 ORY96234.1 - 3.9e-56 191.0 0.1 8.4e-48 163.5 0.0 2.1 1 1 1 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RNA_polI_A34 PF08208.11 ORY96234.1 - 0.16 12.1 7.0 0.28 11.2 7.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_PH PF01138.21 ORY96235.1 - 1e-39 136.0 0.0 1.4e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY96235.1 - 1.7e-07 31.2 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Rax2 PF12768.7 ORY96236.1 - 4.8e-32 111.2 0.6 9.4e-31 106.9 0.1 3.3 3 1 1 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 ORY96236.1 - 1.2e-10 40.8 0.2 3.1e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY96236.1 - 3e-10 39.8 0.1 6.8e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY96236.1 - 1.2e-06 28.0 0.0 2.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kelch_1 PF01344.25 ORY96236.1 - 0.0059 16.2 3.4 0.31 10.7 0.0 5.0 7 0 0 7 7 7 1 Kelch motif DUF5122 PF17164.4 ORY96236.1 - 2.3 8.6 8.3 63 4.0 0.1 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller HC2 PF07382.11 ORY96236.1 - 3.6 7.6 25.0 6.9 6.7 25.0 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Mpv17_PMP22 PF04117.12 ORY96237.1 - 2.6e-23 82.0 0.5 4.3e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mito_carr PF00153.27 ORY96240.1 - 1.5e-66 220.4 3.2 5.3e-24 84.0 0.2 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY96240.1 - 0.0021 17.2 0.2 10 5.2 0.0 3.1 2 1 1 3 3 3 3 Gammaproteobacterial serine protease Bromodomain PF00439.25 ORY96241.1 - 5.5e-25 87.3 0.1 1e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.8 ORY96241.1 - 0.00015 21.3 3.9 0.00031 20.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) AT_hook PF02178.19 ORY96241.1 - 0.34 10.9 6.3 1.5 8.9 6.3 2.2 1 0 0 1 1 1 0 AT hook motif RCC1 PF00415.18 ORY96242.1 - 3.4e-36 123.6 18.6 2e-10 41.1 0.0 7.9 8 1 1 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY96242.1 - 5.1e-27 93.1 25.8 7.3e-10 38.4 2.6 7.9 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat FANCI_S2 PF14676.6 ORY96243.1 - 2.9e-05 24.4 0.1 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 FANCI solenoid 2 PXA PF02194.15 ORY96243.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 0 PXA domain RWD PF05773.22 ORY96244.1 - 6.6e-15 55.4 0.2 2.6e-14 53.5 0.4 2.0 2 0 0 2 2 2 1 RWD domain DEAD PF00270.29 ORY96244.1 - 6.4e-09 35.8 0.2 1.6e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.31 ORY96244.1 - 4.8e-05 23.2 0.3 0.27 11.2 0.1 3.4 3 0 0 3 3 3 2 UBA/TS-N domain AAA_22 PF13401.6 ORY96244.1 - 0.0029 17.9 0.9 0.012 15.8 0.1 2.6 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 ORY96244.1 - 0.024 14.7 0.0 0.11 12.5 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORY96244.1 - 0.099 11.7 0.1 0.56 9.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein M20_dimer PF07687.14 ORY96245.1 - 4.7e-11 42.6 0.0 9.5e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORY96245.1 - 1.9e-05 24.5 0.2 3.4e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 CODH_A_N PF18537.1 ORY96245.1 - 0.077 13.0 0.2 3.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Pex19 PF04614.12 ORY96245.1 - 0.14 11.9 0.8 0.31 10.8 0.2 1.8 2 0 0 2 2 2 0 Pex19 protein family Sybindin PF04099.12 ORY96246.1 - 7.4e-24 84.3 0.0 1.3e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Sybindin-like family PRELI PF04707.14 ORY96247.1 - 2.1e-45 154.4 0.3 2.6e-45 154.1 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family Sel1 PF08238.12 ORY96248.1 - 5e-11 42.9 11.9 0.00097 19.7 0.1 6.2 7 0 0 7 7 7 3 Sel1 repeat zf-MYND PF01753.18 ORY96248.1 - 2.3e-08 34.0 16.5 3.9e-08 33.2 16.5 1.4 1 0 0 1 1 1 1 MYND finger CODH_A_N PF18537.1 ORY96248.1 - 0.034 14.1 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain SYF2 PF08231.12 ORY96249.1 - 7e-46 156.5 11.6 7e-46 156.5 11.6 2.3 1 1 1 2 2 2 1 SYF2 splicing factor bZIP_2 PF07716.15 ORY96250.1 - 9.8e-08 32.0 9.4 6.9e-07 29.3 9.4 1.9 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORY96250.1 - 3.6e-06 27.0 9.7 5.6e-06 26.4 9.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor Csm1_N PF18504.1 ORY96250.1 - 0.00013 22.2 0.8 0.00013 22.2 0.8 1.6 1 1 1 2 2 2 1 Csm1 N-terminal domain HALZ PF02183.18 ORY96250.1 - 0.001 19.2 0.4 0.35 11.1 0.1 2.2 1 1 1 2 2 2 2 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 ORY96250.1 - 0.0014 18.7 1.8 0.0019 18.3 1.8 1.3 1 1 0 1 1 1 1 Centrosome localisation domain of PPC89 DUF5101 PF17031.5 ORY96250.1 - 0.0036 17.4 0.3 0.005 16.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5101) bZIP_Maf PF03131.17 ORY96250.1 - 0.012 16.2 7.4 0.014 15.9 7.4 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor PRKG1_interact PF15898.5 ORY96250.1 - 0.013 16.4 0.5 0.013 16.4 0.5 1.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain NRBF2 PF08961.10 ORY96250.1 - 0.056 13.0 3.1 0.062 12.9 3.1 1.0 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator UPF0242 PF06785.11 ORY96250.1 - 0.067 13.3 2.6 0.068 13.3 2.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 ORY96250.1 - 0.072 12.4 4.1 0.071 12.4 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 ORY96250.1 - 0.091 13.1 2.8 0.1 12.9 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ADIP PF11559.8 ORY96250.1 - 0.095 12.8 5.8 0.11 12.6 5.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 ORY96250.1 - 0.18 11.6 3.9 2 8.2 3.9 2.2 1 1 0 1 1 1 0 Septum formation initiator OrfB_Zn_ribbon PF07282.11 ORY96252.1 - 2.8e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY96253.1 - 0.003 17.5 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Gly_transf_sug PF04488.15 ORY96254.1 - 1.8e-05 25.3 0.1 4e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY96254.1 - 0.18 11.1 1.9 0.32 10.3 1.9 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORY96254.1 - 0.38 10.0 0.4 0.57 9.4 0.4 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain FAD-oxidase_C PF02913.19 ORY96255.1 - 2.6e-55 187.8 0.1 3.4e-55 187.4 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY96255.1 - 8.4e-35 119.5 0.2 1.6e-34 118.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L23 PF00276.20 ORY96256.1 - 1.2e-17 64.0 0.0 2.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 XkdW PF09636.10 ORY96256.1 - 0.056 13.5 0.2 0.092 12.8 0.2 1.4 1 1 0 1 1 1 0 XkdW protein TauD PF02668.16 ORY96257.1 - 9.1e-59 199.4 1.6 9.1e-59 199.4 1.6 1.3 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family MINDY_DUB PF04424.13 ORY96257.1 - 0.035 14.1 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 MINDY deubiquitinase EF-hand_1 PF00036.32 ORY96258.1 - 2e-16 58.3 6.1 5.3e-06 25.6 0.3 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 ORY96258.1 - 3.7e-15 54.5 8.0 1.9e-05 24.2 0.5 4.5 4 0 0 4 4 4 3 EF-hand domain ZZ PF00569.17 ORY96258.1 - 1.7e-11 43.7 6.0 3.2e-11 42.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_5 PF13202.6 ORY96258.1 - 4.5e-11 41.7 4.4 0.0021 17.5 0.2 4.0 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 ORY96258.1 - 5.9e-10 39.5 18.9 4.3e-07 30.3 3.6 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 ORY96258.1 - 1.8e-09 37.3 5.8 0.0065 16.3 0.2 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_2 PF09068.11 ORY96258.1 - 0.012 15.8 0.1 0.17 12.0 0.0 2.6 2 1 0 2 2 2 0 EF hand PI3K_1B_p101 PF10486.9 ORY96258.1 - 0.017 12.9 2.4 0.021 12.6 2.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit EF-hand_14 PF17959.1 ORY96258.1 - 0.042 14.2 0.6 32 5.0 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain Caleosin PF05042.13 ORY96258.1 - 0.063 13.2 7.1 0.17 11.8 0.1 3.5 3 1 1 4 4 4 0 Caleosin related protein EF-hand_9 PF14658.6 ORY96258.1 - 0.12 12.7 0.3 2.5 8.5 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain C1_2 PF03107.16 ORY96258.1 - 0.13 12.6 5.8 0.24 11.7 5.8 1.4 1 0 0 1 1 1 0 C1 domain EF-hand_4 PF12763.7 ORY96258.1 - 0.93 9.5 7.3 2.2 8.3 0.3 3.6 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY96258.1 - 3.2 8.1 7.7 3.1 8.2 0.1 3.4 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF676 PF05057.14 ORY96259.1 - 1.8e-09 37.4 0.0 3.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY96259.1 - 3e-05 24.7 0.0 4.6e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY96259.1 - 0.00016 21.1 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORY96259.1 - 0.00046 20.1 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 ORY96259.1 - 0.00059 19.6 0.1 0.0014 18.4 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 ORY96259.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 ORY96259.1 - 0.0034 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORY96259.1 - 0.031 13.2 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF900 PF05990.12 ORY96259.1 - 0.05 13.1 0.0 0.74 9.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) HELP PF03451.14 ORY96259.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 HELP motif DUF915 PF06028.11 ORY96259.1 - 0.11 11.8 0.1 6.9 5.9 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 ORY96259.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 ORY96259.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase tRNA-synt_2c PF01411.19 ORY96261.1 - 2.2e-164 548.0 0.0 3.1e-164 547.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORY96261.1 - 1.9e-12 47.0 0.2 4.5e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ORY96261.1 - 4.8e-07 30.3 1.2 1.1e-06 29.2 0.1 2.1 2 0 0 2 2 2 1 DHHA1 domain RNA_pol_Rpb1_5 PF04998.17 ORY96262.1 - 1.9e-80 270.1 0.6 3e-80 269.5 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY96262.1 - 1.9e-73 246.2 0.1 3.5e-73 245.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 ORY96262.1 - 6.2e-73 245.9 0.0 1e-72 245.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 ORY96262.1 - 4.1e-36 124.3 0.0 3.2e-35 121.4 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY96262.1 - 1.8e-30 105.1 0.2 5.2e-30 103.6 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RPE65 PF03055.15 ORY96263.1 - 2.9e-93 313.6 0.5 3.5e-93 313.3 0.5 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TauD PF02668.16 ORY96264.1 - 7.2e-58 196.5 1.1 9.6e-58 196.1 1.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MINDY_DUB PF04424.13 ORY96264.1 - 0.021 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 MINDY deubiquitinase F-box-like PF12937.7 ORY96265.1 - 5.9e-10 38.9 1.4 1.6e-09 37.5 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY96265.1 - 0.00068 19.4 0.8 0.0017 18.1 0.8 1.8 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 ORY96265.1 - 0.012 15.4 0.5 0.049 13.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96265.1 - 0.016 15.3 3.6 0.14 12.3 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY96265.1 - 0.29 11.4 4.4 2.9 8.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY96266.1 - 4e-10 39.4 4.3 1.1e-09 38.0 4.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY96266.1 - 6.5e-08 32.3 2.5 1.8e-07 30.8 2.5 1.8 1 0 0 1 1 1 1 F-box domain TPR_21 PF09976.9 ORY96266.1 - 0.00062 19.5 1.3 0.0009 19.0 1.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain DUF2857 PF11198.8 ORY96266.1 - 0.00095 19.0 0.5 0.061 13.1 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2857) TPR_16 PF13432.6 ORY96266.1 - 0.014 16.0 11.3 0.44 11.2 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96266.1 - 0.025 15.4 11.3 0.17 12.7 2.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY96266.1 - 0.03 14.6 0.4 0.28 11.6 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY96266.1 - 0.063 13.8 4.2 0.86 10.2 1.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96266.1 - 0.18 12.0 3.5 1.3 9.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY96266.1 - 0.67 10.7 3.0 31 5.5 0.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY96267.1 - 1.8e-12 46.9 0.4 4.2e-12 45.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY96267.1 - 1.1e-07 31.5 0.5 1.1e-07 31.5 0.5 2.0 2 0 0 2 2 2 1 F-box domain TPR_2 PF07719.17 ORY96267.1 - 0.013 15.5 2.5 0.059 13.5 0.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY96267.1 - 0.041 14.1 0.2 0.093 13.0 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96267.1 - 0.046 14.6 0.4 2.5 9.1 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat M157 PF11624.8 ORY96267.1 - 0.15 11.3 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 MHC class I-like protein M157 TPR_1 PF00515.28 ORY96267.1 - 0.26 11.2 2.6 0.49 10.3 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim17 PF02466.19 ORY96268.1 - 3.9e-10 40.1 6.1 5.6e-10 39.6 5.6 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AAA_16 PF13191.6 ORY96269.1 - 4.9e-11 43.3 0.0 3.2e-10 40.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY96269.1 - 0.00055 20.2 0.3 0.42 10.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ORY96269.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 ORY96269.1 - 0.0032 17.2 0.0 0.0094 15.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad17 PF03215.15 ORY96269.1 - 0.021 14.8 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 ORY96269.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 ORY96269.1 - 0.14 12.7 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4203 PF13886.6 ORY96270.1 - 1.5e-28 99.9 21.6 1.6e-28 99.7 21.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Holin_2-3 PF13272.6 ORY96270.1 - 0.25 11.6 5.8 1.3 9.4 1.7 2.6 2 1 0 2 2 2 0 Putative 2/3 transmembrane domain holin Bromodomain PF00439.25 ORY96272.1 - 7.9e-20 70.7 0.3 1.7e-19 69.7 0.3 1.6 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.31 ORY96272.1 - 0.00099 19.3 1.3 0.0019 18.4 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain bVLRF1 PF18826.1 ORY96273.1 - 4.3e-60 201.9 0.1 1.1e-59 200.5 0.1 1.8 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 ORY96273.1 - 2.7e-06 27.6 0.0 1.2e-05 25.4 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY96273.1 - 0.002 18.5 0.3 0.0047 17.3 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 ORY96273.1 - 0.022 15.3 0.0 0.058 14.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 ORY96273.1 - 0.086 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3810 PF12725.7 ORY96273.1 - 4 6.7 4.3 0.9 8.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) Ank_2 PF12796.7 ORY96274.1 - 1.8e-18 66.9 0.0 1.9e-10 41.2 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY96274.1 - 1.2e-15 57.7 0.1 6.3e-06 26.6 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY96274.1 - 2.8e-13 48.7 0.2 3.7e-05 23.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY96274.1 - 5.5e-12 45.7 0.6 0.00018 21.7 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY96274.1 - 1.4e-11 44.3 1.0 0.014 15.9 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat SUIM_assoc PF16619.5 ORY96274.1 - 0.0001 22.3 1.0 0.00074 19.5 1.0 2.6 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 MPS2 PF17060.5 ORY96274.1 - 0.59 9.3 2.2 0.92 8.7 2.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Siah-Interact_N PF09032.11 ORY96274.1 - 8.5 6.8 10.5 4.3 7.7 0.7 3.1 3 0 0 3 3 3 0 Siah interacting protein, N terminal Pkinase PF00069.25 ORY96275.1 - 8.4e-64 215.5 0.0 1.5e-63 214.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96275.1 - 1e-36 126.6 0.0 1.9e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY96275.1 - 1.7e-05 24.3 0.0 0.00023 20.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY96275.1 - 5.2e-05 22.7 0.6 0.00014 21.3 0.6 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY96275.1 - 0.0083 15.7 0.1 0.031 13.9 0.1 2.0 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 ORY96275.1 - 1 9.3 10.8 2.3 8.1 0.3 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.20 ORY96276.1 - 2.1e-25 89.3 0.0 6.1e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY96276.1 - 7.4e-09 36.2 0.0 0.00025 21.4 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY96276.1 - 0.007 16.0 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cript PF10235.9 ORY96278.1 - 2.9e-34 117.5 12.0 2.9e-34 117.5 12.0 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF2616 PF11077.8 ORY96278.1 - 0.002 17.9 5.2 0.0023 17.7 5.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2616) DUF2039 PF10217.9 ORY96278.1 - 0.025 14.9 21.8 0.89 9.9 21.8 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 ORY96278.1 - 0.028 14.8 10.2 0.049 14.0 5.4 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal DZR PF12773.7 ORY96278.1 - 0.034 14.2 13.7 0.28 11.2 9.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon Ribos_L4_asso_C PF14374.6 ORY96278.1 - 0.04 14.0 0.3 0.057 13.5 0.3 1.2 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain Gin PF10764.9 ORY96278.1 - 0.068 13.1 8.8 0.99 9.4 0.1 2.9 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zinc_ribbon_2 PF13240.6 ORY96278.1 - 0.084 12.6 10.2 7.7 6.4 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.11 ORY96278.1 - 0.16 12.1 8.6 0.2 11.8 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PolC_DP2 PF03833.13 ORY96278.1 - 0.4 8.5 6.0 0.44 8.3 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_15 PF17032.5 ORY96278.1 - 0.42 11.4 15.9 1.2 9.9 11.9 2.6 2 1 0 2 2 2 0 zinc-ribbon family HypA PF01155.19 ORY96278.1 - 2.3 8.3 12.5 0.57 10.2 7.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 ORY96278.1 - 2.5 8.2 17.4 32 4.6 17.4 2.2 1 1 0 1 1 1 0 zinc-ribbons NinF PF05810.12 ORY96278.1 - 2.6 8.0 14.3 2.4 8.1 4.2 2.9 2 1 1 3 3 3 0 NinF protein DUF4428 PF14471.6 ORY96278.1 - 3.7 7.5 15.4 0.42 10.6 0.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) zf-piccolo PF05715.13 ORY96278.1 - 4 7.6 11.9 2.9 8.1 8.1 2.3 2 1 0 2 2 2 0 Piccolo Zn-finger WAK_assoc PF14380.6 ORY96278.1 - 5.9 7.7 14.9 6.1 7.6 3.3 2.5 1 1 1 2 2 2 0 Wall-associated receptor kinase C-terminal Tnp_zf-ribbon_2 PF13842.6 ORY96278.1 - 9.3 7.2 19.3 41 5.1 14.8 3.1 2 1 1 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DHBP_synthase PF00926.19 ORY96279.1 - 0.043 13.3 0.1 0.043 13.3 0.1 1.1 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase DDT PF02791.17 ORY96281.1 - 2e-13 50.4 0.0 5e+02 1.1 0.0 19.4 18 0 0 18 18 18 0 DDT domain GSDH PF07995.11 ORY96281.1 - 2.1e-10 40.4 9.6 42 3.3 0.0 16.6 14 7 13 27 27 27 1 Glucose / Sorbosone dehydrogenase Sigma54_DBD PF04552.13 ORY96281.1 - 2.6e-10 40.2 122.3 2.7 7.7 0.2 25.2 12 9 19 34 34 34 21 Sigma-54, DNA binding domain Y2_Tnp PF04986.13 ORY96281.1 - 0.00011 22.4 0.5 83 3.2 0.0 7.3 6 1 1 7 7 7 0 Putative transposase Fumarate_red_C PF02300.17 ORY96282.1 - 0.0071 16.4 0.4 0.0094 16.0 0.3 1.3 1 1 0 1 1 1 1 Fumarate reductase subunit C MFS_1 PF07690.16 ORY96283.1 - 1e-13 51.0 35.4 1e-13 51.0 35.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY96283.1 - 1.2e-10 41.3 5.3 1.2e-10 41.3 5.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sm_multidrug_ex PF06695.11 ORY96283.1 - 0.25 12.0 4.3 3.6 8.3 0.0 3.3 3 1 0 3 3 3 0 Putative small multi-drug export protein PITH PF06201.13 ORY96284.1 - 2.2e-44 151.4 0.0 2.6e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain zf-C2H2 PF00096.26 ORY96285.1 - 6e-10 39.0 9.0 1.3e-05 25.4 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY96285.1 - 7.5e-08 32.6 6.9 0.00037 21.1 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY96285.1 - 8.7e-08 32.3 12.9 6.4e-05 23.2 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY96285.1 - 0.0011 19.2 2.9 0.0031 17.8 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORY96285.1 - 0.0013 18.5 3.7 0.54 10.2 0.2 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 ORY96285.1 - 0.0029 17.9 0.3 0.0057 16.9 0.3 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORY96285.1 - 0.0044 17.0 5.3 0.036 14.1 0.8 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 ORY96285.1 - 0.043 14.2 0.6 0.043 14.2 0.6 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RNA_pol_Rpb1_4 PF05000.17 ORY96285.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 zf-BED PF02892.15 ORY96285.1 - 0.22 11.6 3.4 1.6 8.8 0.2 2.6 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 ORY96285.1 - 5.5 6.8 7.4 3.9 7.3 0.2 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain bZIP_1 PF00170.21 ORY96286.1 - 1.7e-08 34.4 2.8 5.4e-08 32.8 2.8 1.9 1 0 0 1 1 1 1 bZIP transcription factor Cob_adeno_trans PF01923.18 ORY96286.1 - 0.011 15.8 1.2 0.033 14.3 1.2 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Polysacc_lyase PF14099.6 ORY96287.1 - 8.8e-06 25.7 1.4 1.2e-05 25.3 1.0 1.5 1 1 0 1 1 1 1 Polysaccharide lyase bZIP_2 PF07716.15 ORY96288.1 - 4.5e-05 23.4 11.7 6.8e-05 22.9 11.0 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY96288.1 - 8.3e-05 22.6 7.0 0.00016 21.7 7.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Rootletin PF15035.6 ORY96288.1 - 0.00053 20.1 1.1 0.00072 19.6 1.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion NRBF2 PF08961.10 ORY96288.1 - 0.012 15.2 0.6 0.018 14.7 0.6 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Csm1_N PF18504.1 ORY96288.1 - 0.047 14.0 1.4 0.071 13.4 0.8 1.7 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF5101 PF17031.5 ORY96288.1 - 0.072 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) UPF0242 PF06785.11 ORY96288.1 - 0.11 12.7 1.1 0.14 12.2 1.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_Maf PF03131.17 ORY96288.1 - 0.19 12.3 11.7 0.34 11.5 11.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor ADIP PF11559.8 ORY96288.1 - 1.1 9.4 10.7 1.6 8.8 10.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 ORY96288.1 - 9.8 4.6 11.7 18 3.7 11.7 1.3 1 1 0 1 1 1 0 Macoilin family Glyco_hydro_45 PF02015.16 ORY96289.1 - 4.9e-75 252.0 19.3 4.9e-75 252.0 19.3 2.5 1 1 1 3 3 3 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 ORY96289.1 - 9.8e-10 38.2 13.5 6.5e-09 35.6 13.5 2.6 1 0 0 1 1 1 1 Fungal cellulose binding domain SpoIIIAH PF12685.7 ORY96289.1 - 0.99 9.2 11.8 1.5 8.6 11.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Dicty_REP PF05086.12 ORY96289.1 - 1.5 6.7 5.8 2 6.3 5.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.9 ORY96289.1 - 4.6 5.7 8.6 5.5 5.4 8.6 1.2 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_47 PF01532.20 ORY96290.1 - 1e-126 423.6 0.0 1.2e-126 423.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RAP1 PF07218.11 ORY96291.1 - 0.042 12.1 2.1 0.06 11.6 2.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4452 PF14618.6 ORY96291.1 - 6.7 6.5 19.6 2.3 8.1 4.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4452) TauD PF02668.16 ORY96292.1 - 1.6e-46 159.3 0.3 2.5e-46 158.6 0.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GDP_Man_Dehyd PF16363.5 ORY96293.1 - 3.7e-60 204.1 0.0 4.9e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY96293.1 - 7.7e-47 159.8 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY96293.1 - 6.1e-12 45.1 0.0 8.4e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY96293.1 - 1.3e-10 40.9 0.0 1.7e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY96293.1 - 2.9e-09 36.5 0.1 2.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ORY96293.1 - 2.6e-08 33.3 0.0 4.9e-05 22.6 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 ORY96293.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Cyt-b5 PF00173.28 ORY96294.1 - 2.5e-13 50.0 0.0 3.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UPF0014 PF03649.13 ORY96295.1 - 1.5e-56 191.4 15.8 2e-56 191.0 15.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Arrestin_N PF00339.29 ORY96296.1 - 1.3e-08 35.0 0.0 2.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain RAB3GAP2_N PF14655.6 ORY96297.1 - 3.9e-95 319.5 0.0 4.7e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Pkinase PF00069.25 ORY96298.1 - 2.9e-72 243.2 0.0 3.7e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96298.1 - 8e-35 120.4 0.0 1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORY96298.1 - 8e-12 45.3 0.1 1.6e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 ORY96298.1 - 8.8e-05 21.5 0.0 0.00019 20.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 ORY96298.1 - 0.00054 19.1 0.2 0.00081 18.5 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Yop-YscD_cpl PF16697.5 ORY96298.1 - 0.003 17.8 0.0 0.008 16.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 ORY96298.1 - 0.0052 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY96298.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY96298.1 - 0.27 10.1 1.9 0.21 10.5 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain DEAD PF00270.29 ORY96299.1 - 2.9e-43 147.7 0.0 5.9e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY96299.1 - 2.1e-19 69.9 0.0 1e-18 67.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY96299.1 - 2.1e-16 59.9 1.2 4.4e-16 58.8 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY96299.1 - 2.6e-05 24.3 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY96299.1 - 0.044 14.1 1.9 0.12 12.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain DNA_pol_phi PF04931.13 ORY96299.1 - 1.7 6.6 14.7 3.3 5.7 14.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi PAPS_reduct PF01507.19 ORY96299.1 - 3.1 7.8 4.6 42 4.1 0.0 3.1 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Acyl-CoA_dh_1 PF00441.24 ORY96300.1 - 2.5e-46 157.6 3.7 4.1e-46 156.9 3.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY96300.1 - 4.9e-27 94.8 0.6 1.4e-26 93.4 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY96300.1 - 1.2e-21 76.7 0.0 2.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY96300.1 - 1.3e-20 74.0 0.4 4.1e-20 72.4 0.4 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 ORY96302.1 - 1.6e-73 248.1 0.1 2.1e-73 247.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S28e PF01200.18 ORY96304.1 - 1.6e-32 111.3 1.0 1.8e-32 111.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORY96304.1 - 0.082 13.3 0.0 0.085 13.2 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal ADIP PF11559.8 ORY96305.1 - 2e-22 79.9 13.0 2e-22 79.9 13.0 3.0 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 ORY96305.1 - 0.0009 19.8 15.7 0.0009 19.8 15.7 3.5 2 1 1 3 3 3 1 Apg6 coiled-coil region ATG16 PF08614.11 ORY96305.1 - 0.0036 17.6 10.4 0.0036 17.6 10.4 3.6 3 1 1 4 4 4 2 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 ORY96305.1 - 1.2 9.1 7.2 0.55 10.3 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 ORY96305.1 - 9.7 6.5 12.2 0.16 12.2 1.0 3.1 2 1 1 3 3 3 0 Rx N-terminal domain DUF4407 PF14362.6 ORY96305.1 - 9.9 5.4 21.9 1.1 8.5 7.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lipase_3 PF01764.25 ORY96306.1 - 5.1e-14 52.3 0.0 1.2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 ORY96306.1 - 9.7e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY96306.1 - 0.00027 21.6 0.3 0.00027 21.6 0.3 2.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY96306.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WD40 PF00400.32 ORY96307.1 - 3.1e-31 106.9 8.1 6.4e-08 33.1 0.1 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Bromodomain PF00439.25 ORY96307.1 - 8e-12 45.1 0.1 1.6e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 ORY96307.1 - 2e-09 37.6 0.1 0.13 12.6 0.0 5.1 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY96307.1 - 3.4e-05 23.0 0.1 0.68 8.8 0.0 4.3 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY96307.1 - 0.004 15.9 0.5 4.8 5.7 0.1 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Kelch_6 PF13964.6 ORY96307.1 - 0.093 13.1 0.2 14 6.2 0.1 3.1 2 0 0 2 2 2 0 Kelch motif Nucleoporin_N PF08801.11 ORY96307.1 - 0.11 11.2 0.1 6 5.5 0.0 3.3 3 1 0 3 3 3 0 Nup133 N terminal like Med31 PF05669.12 ORY96307.1 - 0.17 11.9 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 SOH1 CAP_GLY PF01302.25 ORY96309.1 - 1.2e-21 76.5 0.1 1.5e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain p450 PF00067.22 ORY96310.1 - 7.3e-87 292.0 0.0 9e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY96311.1 - 2.2e-86 290.5 0.0 2.7e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.26 ORY96312.1 - 1.7e-37 128.1 0.1 2.2e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LRR_4 PF12799.7 ORY96313.1 - 2.7e-34 116.6 39.4 2.4e-06 27.8 2.3 7.7 7 0 0 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY96313.1 - 1.4e-24 85.6 40.8 5.8e-07 29.2 1.1 7.0 4 3 2 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 ORY96313.1 - 9.4e-10 38.3 17.4 0.0015 18.1 1.0 4.2 2 1 1 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 ORY96313.1 - 6.1 7.8 38.3 15 6.6 0.4 10.4 11 1 0 11 11 11 0 Leucine Rich Repeat POPLD PF08170.12 ORY96314.1 - 0.23 11.8 5.4 0.13 12.6 1.0 2.6 2 0 0 2 2 2 0 POPLD (NUC188) domain Peptidase_S49_N PF08496.10 ORY96314.1 - 4.1 7.4 5.0 18 5.3 0.9 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RNB PF00773.19 ORY96315.1 - 1.1e-52 179.5 0.0 1.9e-52 178.6 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY96315.1 - 1.2e-18 66.9 0.0 2.3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 ORY96315.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain HLH PF00010.26 ORY96316.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1-E2_ATPase PF00122.20 ORY96317.1 - 2.2e-36 125.1 0.7 5.6e-36 123.8 0.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 ORY96317.1 - 4e-29 101.2 0.5 4e-29 101.2 0.5 2.7 3 0 0 3 3 3 1 P5-type ATPase cation transporter Hydrolase PF00702.26 ORY96317.1 - 4.3e-09 37.0 0.3 0.05 13.9 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY96317.1 - 2.5e-06 27.1 0.0 6.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY96317.1 - 0.0003 20.8 0.0 0.0016 18.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Spt5_N PF11942.8 ORY96317.1 - 1.6 9.8 9.4 4.7 8.3 9.4 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF3446 PF11928.8 ORY96317.1 - 1.8 8.9 9.2 7.5 6.9 9.2 2.0 1 0 0 1 1 1 0 Early growth response N-terminal domain Cation_ATPase_C PF00689.21 ORY96317.1 - 1.9 8.2 13.3 0.051 13.3 5.2 2.3 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Syntaxin-18_N PF10496.9 ORY96318.1 - 5.8e-12 45.7 6.2 1.1e-11 44.8 0.0 3.2 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 ORY96318.1 - 0.00065 19.6 1.4 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 1 SNARE domain DUF5319 PF17252.2 ORY96318.1 - 0.93 9.7 4.6 1.8 8.8 0.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5319) Myosin_head PF00063.21 ORY96319.1 - 6.3e-274 910.4 8.8 1.1e-273 909.5 8.8 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY96319.1 - 8.2e-28 96.7 0.7 8.2e-28 96.7 0.7 3.2 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 ORY96319.1 - 4.5e-16 57.1 41.5 1.3e-06 27.7 1.5 6.6 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.6 ORY96319.1 - 0.022 15.0 1.1 0.077 13.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain PSII_Pbs27 PF13326.6 ORY96319.1 - 0.052 13.9 3.4 0.16 12.3 0.4 2.6 2 0 0 2 2 2 0 Photosystem II Pbs27 NACHT PF05729.12 ORY96319.1 - 0.057 13.3 0.4 2.1 8.2 0.0 2.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 ORY96319.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Myosin_N PF02736.19 ORY96319.1 - 0.13 12.1 0.2 0.42 10.5 0.1 1.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.12 ORY96319.1 - 0.99 9.4 7.7 11 6.1 5.5 3.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 ORY96319.1 - 1.1 9.9 17.1 0.95 10.1 0.4 4.5 2 1 1 3 3 3 0 SlyX FlaC_arch PF05377.11 ORY96319.1 - 4.1 7.9 5.2 8.3 6.9 0.3 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran PF00005.27 ORY96319.1 - 7.9 7.0 7.0 1.8 9.1 0.0 3.3 2 1 0 2 2 1 0 ABC transporter DUF1640 PF07798.11 ORY96320.1 - 9.9e-64 214.6 10.7 1.1e-63 214.4 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Phage_GP20 PF06810.11 ORY96320.1 - 0.0014 18.5 7.5 0.0017 18.1 7.5 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 HALZ PF02183.18 ORY96320.1 - 0.0039 17.4 2.1 0.017 15.4 1.8 2.2 2 1 0 2 2 2 1 Homeobox associated leucine zipper Uso1_p115_C PF04871.13 ORY96320.1 - 0.041 14.3 8.4 0.031 14.6 3.8 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 ORY96320.1 - 0.045 12.8 4.8 0.06 12.4 4.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec2p PF06428.11 ORY96320.1 - 0.056 13.4 11.3 0.15 12.1 7.3 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p HMMR_C PF15908.5 ORY96320.1 - 0.061 13.6 3.2 5.2 7.3 1.2 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF4854 PF16146.5 ORY96320.1 - 0.09 13.1 1.9 0.14 12.5 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4854) Baculo_PEP_C PF04513.12 ORY96320.1 - 0.2 11.7 1.0 1.1 9.2 0.4 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 ORY96320.1 - 0.24 11.8 6.1 4.1 7.9 1.6 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 ORY96320.1 - 0.41 10.9 3.9 0.91 9.8 1.0 2.5 1 1 1 2 2 2 0 Haemolysin XhlA Remorin_C PF03763.13 ORY96320.1 - 0.94 9.4 7.9 1.5 8.7 7.9 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region BST2 PF16716.5 ORY96320.1 - 1.1 9.9 9.0 0.19 12.3 3.0 2.4 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 HalX PF08663.10 ORY96320.1 - 1.1 9.6 8.9 0.87 10.0 0.8 2.6 3 0 0 3 3 2 0 HalX domain DivIC PF04977.15 ORY96320.1 - 1.7 8.4 9.3 0.57 10.0 2.9 2.9 1 1 2 3 3 3 0 Septum formation initiator YabA PF06156.13 ORY96320.1 - 1.8 9.3 8.3 4 8.1 6.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Lzipper-MIP1 PF14389.6 ORY96320.1 - 2.9 8.3 9.8 2.3 8.6 4.7 2.9 2 2 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PTPlike_phytase PF14566.6 ORY96320.1 - 5.7 7.0 8.7 11 6.0 3.2 2.1 1 1 1 2 2 2 0 Inositol hexakisphosphate DUF883 PF05957.13 ORY96320.1 - 7.1 7.3 6.7 3.2 8.4 2.5 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Opi1 PF08618.10 ORY96321.1 - 3.7e-62 210.9 26.1 3.8e-48 164.8 7.7 3.8 2 1 1 4 4 4 3 Transcription factor Opi1 Ipi1_N PF12333.8 ORY96321.1 - 0.018 15.6 0.3 0.077 13.6 0.3 2.2 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Nup192 PF11894.8 ORY96321.1 - 0.037 11.2 0.1 0.049 10.8 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 BsuBI_PstI_RE_N PF17728.1 ORY96321.1 - 0.075 12.9 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain bZIP_2 PF07716.15 ORY96322.1 - 1.3e-09 37.9 9.8 1.3e-09 37.9 9.8 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY96322.1 - 5.3e-09 36.0 10.4 7.6e-09 35.6 10.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor UPF0242 PF06785.11 ORY96322.1 - 0.00087 19.5 0.7 0.00097 19.3 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Tmemb_cc2 PF10267.9 ORY96322.1 - 0.0055 15.9 1.3 0.0061 15.8 1.3 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein bZIP_Maf PF03131.17 ORY96322.1 - 0.0057 17.2 6.9 0.0076 16.7 6.9 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 ORY96322.1 - 0.0099 15.6 2.0 0.014 15.2 2.0 1.3 1 0 0 1 1 1 1 Septum formation initiator DUF737 PF05300.11 ORY96322.1 - 0.011 16.1 2.8 0.013 15.9 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF2400 PF09674.10 ORY96322.1 - 0.044 13.8 0.3 0.05 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) HAUS6_N PF14661.6 ORY96322.1 - 0.046 13.3 2.3 0.052 13.1 2.3 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ZapB PF06005.12 ORY96322.1 - 0.053 14.0 3.0 0.068 13.6 2.6 1.3 1 1 0 1 1 1 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 ORY96322.1 - 0.31 11.1 6.3 0.49 10.4 6.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Mto2_bdg PF12808.7 ORY96322.1 - 0.96 9.8 9.0 0.19 12.1 3.0 2.1 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FYRN PF05964.14 ORY96323.1 - 1e-17 63.7 0.6 1.6e-17 63.1 0.6 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY96323.1 - 1.5e-14 53.9 0.0 3e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus Smg8_Smg9 PF10220.9 ORY96323.1 - 0.013 13.9 0.9 0.016 13.5 0.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF4820 PF16091.5 ORY96323.1 - 0.11 11.9 4.7 0.15 11.4 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF1980 PF09323.10 ORY96323.1 - 0.77 9.6 3.0 1.3 8.9 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CK_II_beta PF01214.18 ORY96324.1 - 1.5e-56 191.1 0.0 2e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit BNIP2 PF12496.8 ORY96324.1 - 0.004 17.6 0.0 0.0052 17.2 0.0 1.2 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Dynactin_p62 PF05502.13 ORY96324.1 - 0.032 13.0 1.8 0.045 12.5 1.8 1.1 1 0 0 1 1 1 0 Dynactin p62 family DUF1180 PF06679.12 ORY96325.1 - 0.0052 17.2 0.0 0.0052 17.2 0.0 3.0 1 1 1 2 2 1 1 Protein of unknown function (DUF1180) SARAF PF06682.12 ORY96325.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TMEM154 PF15102.6 ORY96325.1 - 0.021 14.8 1.3 0.21 11.5 0.0 2.4 2 1 0 2 2 2 0 TMEM154 protein family Tmemb_9 PF05434.11 ORY96325.1 - 0.027 14.4 1.2 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 TMEM9 DUF4083 PF13314.6 ORY96325.1 - 0.034 14.1 1.1 0.11 12.5 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Orf78 PF06024.12 ORY96325.1 - 0.045 14.1 0.2 3.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) DUF5305 PF17231.2 ORY96325.1 - 0.065 12.6 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF5527 PF17665.1 ORY96325.1 - 0.099 12.2 0.4 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5527) EphA2_TM PF14575.6 ORY96325.1 - 0.11 13.4 5.4 1.1 10.2 5.4 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 ORY96325.1 - 0.11 12.4 0.3 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain Saf_2TM PF18303.1 ORY96325.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain CYYR1 PF10873.8 ORY96325.1 - 0.41 11.1 4.1 1.8 9.0 4.1 1.8 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Presenilin PF01080.17 ORY96325.1 - 1.6 7.5 3.8 23 3.6 2.6 2.1 2 0 0 2 2 2 0 Presenilin Fer4_5 PF12801.7 ORY96327.1 - 0.2 11.6 1.6 0.67 10.0 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Rogdi_lz PF10259.9 ORY96328.1 - 7.4e-32 110.9 0.5 1.2e-31 110.1 0.5 1.4 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein VIT1 PF01988.19 ORY96329.1 - 8.3e-71 238.3 0.2 8.3e-71 238.3 0.2 1.5 2 0 0 2 2 2 1 VIT family 7TMR-DISM_7TM PF07695.11 ORY96329.1 - 0.02 14.8 3.7 0.033 14.1 3.7 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling Androgen_recep PF02166.16 ORY96329.1 - 5.5 5.7 8.8 7.9 5.2 8.8 1.2 1 0 0 1 1 1 0 Androgen receptor SatRNA_48 PF17485.2 ORY96330.1 - 0.1 11.7 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein Polysacc_deac_1 PF01522.21 ORY96331.1 - 2.9e-11 43.3 0.1 5.2e-11 42.5 0.1 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase DEAD PF00270.29 ORY96332.1 - 2.5e-48 164.1 0.0 5e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY96332.1 - 1.3e-31 109.2 0.0 3e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY96332.1 - 0.0001 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY96332.1 - 0.0066 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 ORY96332.1 - 0.098 11.4 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4682 PF15733.5 ORY96333.1 - 0.17 12.5 0.1 0.27 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) DUF2408 PF10303.9 ORY96334.1 - 2.2e-05 25.1 1.0 2.9e-05 24.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) Apolipoprotein PF01442.18 ORY96334.1 - 0.0059 16.5 3.5 0.0085 16.0 3.5 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain TetR_C_8 PF14278.6 ORY96334.1 - 0.024 14.7 0.8 0.036 14.2 0.7 1.3 1 1 0 1 1 1 0 Transcriptional regulator C-terminal region PCRF PF03462.18 ORY96334.1 - 0.025 14.5 2.0 0.03 14.2 2.0 1.0 1 0 0 1 1 1 0 PCRF domain WXG100 PF06013.12 ORY96334.1 - 0.37 11.0 4.9 12 6.2 0.2 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Cob_adeno_trans PF01923.18 ORY96334.1 - 1.2 9.3 3.7 1.3 9.2 1.9 1.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase SMC_N PF02463.19 ORY96335.1 - 1.2e-45 155.6 0.0 1.9e-45 155.0 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY96335.1 - 6.8e-31 107.0 0.0 2.4e-30 105.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY96335.1 - 4.5e-06 26.7 1.8 8.7e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RPW8 PF05659.11 ORY96335.1 - 0.076 12.7 21.3 0.36 10.5 0.0 5.4 6 0 0 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Hyd_WA PF06462.12 ORY96335.1 - 0.084 12.9 1.6 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 Propeller DUF2703 PF10865.8 ORY96335.1 - 0.87 9.8 7.7 1.1 9.5 0.2 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2703) CENP-H PF05837.12 ORY96336.1 - 3e-13 50.1 11.6 3e-13 50.1 11.6 1.7 2 0 0 2 2 2 1 Centromere protein H (CENP-H) FUSC PF04632.12 ORY96336.1 - 0.33 9.4 4.4 0.4 9.1 4.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 ORY96336.1 - 1.6 7.5 18.0 0.093 11.6 12.0 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Mannosyl_trans2 PF04188.13 ORY96337.1 - 5.1e-76 256.8 23.6 6e-76 256.5 23.6 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) VTC PF09359.10 ORY96338.1 - 1.9e-84 283.3 0.0 3.6e-84 282.4 0.0 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 ORY96338.1 - 1.1e-12 48.2 4.0 2.2e-12 47.2 4.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 ORY96338.1 - 1.3e-12 48.4 14.4 2.9e-08 34.1 0.5 4.1 2 1 2 4 4 4 3 SPX domain Foie-gras_1 PF11817.8 ORY96339.1 - 1.3e-41 142.9 0.5 1.9e-39 135.8 0.1 3.0 3 1 0 3 3 3 1 Foie gras liver health family 1 Gryzun PF07919.12 ORY96339.1 - 2e-37 129.2 0.1 4.7e-35 121.4 0.1 2.7 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 ORY96339.1 - 4.4e-05 23.4 0.0 9.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF974 PF06159.13 ORY96339.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF974) CARDB PF07705.11 ORY96339.1 - 0.059 13.6 0.2 16 5.8 0.0 2.7 2 0 0 2 2 2 0 CARDB TPR_19 PF14559.6 ORY96339.1 - 0.078 13.5 0.0 0.59 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY96339.1 - 0.14 12.5 0.8 0.94 9.8 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY96339.1 - 0.22 11.8 0.6 25 5.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cytochrom_B558a PF05038.13 ORY96340.1 - 2.3 7.8 4.2 9.5 5.7 0.4 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Vac_ImportDeg PF09783.9 ORY96341.1 - 1.6e-56 190.5 1.8 2.1e-56 190.2 1.8 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein TMEM138 PF14935.6 ORY96341.1 - 0.19 12.4 0.2 0.28 11.8 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 138 Cupin_6 PF12852.7 ORY96342.1 - 0.0091 15.7 0.0 0.0094 15.7 0.0 1.0 1 0 0 1 1 1 1 Cupin LRR_3 PF07725.12 ORY96342.1 - 0.095 12.6 0.1 3 7.8 0.2 2.1 2 0 0 2 2 2 0 Leucine Rich Repeat GCV_H PF01597.19 ORY96343.1 - 5e-06 26.4 0.0 7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein IIGP PF05049.13 ORY96344.1 - 2.9e-21 76.0 0.0 3.3e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 ORY96344.1 - 2.4e-06 27.6 0.0 3.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ORY96344.1 - 5.6e-05 23.3 0.0 7.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 ORY96344.1 - 0.0011 19.5 0.0 0.0016 19.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 ORY96344.1 - 0.0013 18.2 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ORY96344.1 - 0.0057 16.6 0.0 0.01 15.7 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ORY96344.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_30 PF13604.6 ORY96344.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORY96344.1 - 0.034 14.2 0.3 0.089 12.8 0.3 1.7 1 1 1 2 2 2 0 Dynamin family AIG1 PF04548.16 ORY96344.1 - 0.044 13.1 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Tox-PLDMTX PF15645.6 ORY96344.1 - 0.057 13.7 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold Ras PF00071.22 ORY96344.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Ras family AAA_29 PF13555.6 ORY96344.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 ORY96344.1 - 0.18 11.1 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 ORY96344.1 - 0.25 11.7 0.0 0.32 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-C3HC PF07967.13 ORY96345.1 - 1.6e-17 63.8 0.1 3.7e-14 52.9 0.0 2.6 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 ORY96345.1 - 1.4e-08 34.8 2.6 1.6e-08 34.5 0.2 2.5 2 0 0 2 2 2 1 Rsm1-like EBP PF05241.12 ORY96346.1 - 0.012 15.1 7.3 0.016 14.7 7.3 1.2 1 0 0 1 1 1 0 Emopamil binding protein Ureidogly_lyase PF04115.12 ORY96346.1 - 0.21 11.3 0.2 0.28 10.9 0.2 1.1 1 0 0 1 1 1 0 Ureidoglycolate lyase PAS_3 PF08447.12 ORY96347.1 - 2.1e-11 43.9 0.0 4.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORY96347.1 - 5.3e-08 32.8 1.5 3.1e-07 30.4 0.0 2.1 1 1 1 2 2 2 1 PAS fold PAS_4 PF08448.10 ORY96347.1 - 1.5e-05 25.2 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold GATA PF00320.27 ORY96347.1 - 3.8e-05 23.2 3.3 6.5e-05 22.4 3.3 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.7 ORY96347.1 - 9.1e-05 22.7 0.2 0.00031 20.9 0.0 1.9 1 1 1 2 2 2 1 PAS domain PAS_8 PF13188.7 ORY96347.1 - 0.00037 20.4 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain YabA PF06156.13 ORY96347.1 - 0.32 11.7 3.6 0.67 10.6 3.5 1.6 1 1 0 1 1 1 0 Initiation control protein YabA ATG13 PF10033.9 ORY96348.1 - 6.4e-66 222.5 0.3 7.8e-66 222.2 0.3 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 MIP-T3_C PF17749.1 ORY96348.1 - 0.014 15.4 0.4 0.022 14.7 0.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region PP2C PF00481.21 ORY96350.1 - 1.7e-82 276.9 0.0 2.2e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY96350.1 - 0.0046 16.6 0.0 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C GTP_cyclohydroI PF01227.22 ORY96351.1 - 5.7e-78 260.4 0.4 6.6e-78 260.2 0.4 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ORY96351.1 - 6e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein DUF3638 PF12340.8 ORY96351.1 - 0.037 13.4 0.1 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) Zn_clus PF00172.18 ORY96353.1 - 2.7e-05 24.2 10.0 4.2e-05 23.6 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 ORY96353.1 - 0.004 17.2 17.1 0.004 17.2 17.1 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PAS PF00989.25 ORY96353.1 - 0.011 15.7 3.2 0.059 13.4 0.0 2.4 2 0 0 2 2 2 0 PAS fold Androgen_recep PF02166.16 ORY96353.1 - 0.18 10.6 13.9 0.33 9.7 13.9 1.4 1 0 0 1 1 1 0 Androgen receptor Endostatin PF06482.11 ORY96353.1 - 0.71 9.3 10.2 0.063 12.7 4.5 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin PAS_3 PF08447.12 ORY96353.1 - 0.75 10.1 4.7 2 8.7 0.0 2.4 2 0 0 2 2 2 0 PAS fold PAT1 PF09770.9 ORY96353.1 - 6.7 4.8 19.8 11 4.2 19.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3007 PF11460.8 ORY96354.1 - 0.16 12.2 0.9 0.49 10.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) RRM_1 PF00076.22 ORY96355.1 - 9e-11 41.4 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 ORY96355.1 - 5.8e-06 27.0 0.0 1.1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Nup35_RRM_2 PF14605.6 ORY96355.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CTK3 PF12243.8 ORY96355.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Glyco_hydro_31 PF01055.26 ORY96356.1 - 1.1e-97 328.1 2.8 1.5e-97 327.6 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY96356.1 - 1.5e-11 44.5 1.2 7.5e-11 42.2 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 ORY96356.1 - 0.00026 21.2 0.3 0.00094 19.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 ORY96356.1 - 0.0081 16.4 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Oxidored_q5_N PF01059.17 ORY96356.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus LAT PF15234.6 ORY96358.1 - 0.015 15.1 3.3 0.015 15.1 3.3 1.5 2 0 0 2 2 2 0 Linker for activation of T-cells NICE-3 PF07406.11 ORY96358.1 - 0.019 14.9 0.2 0.034 14.1 0.2 1.6 1 1 0 1 1 1 0 NICE-3 protein DUF4129 PF13559.6 ORY96358.1 - 0.11 12.7 0.1 0.32 11.3 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) AP3D1 PF06375.11 ORY96359.1 - 0.0081 16.4 11.9 0.0081 16.4 11.9 2.4 2 1 0 2 2 2 1 AP-3 complex subunit delta-1 DUF755 PF05501.11 ORY96359.1 - 1.9 8.8 33.5 0.87 9.9 15.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Peptidase_S49_N PF08496.10 ORY96359.1 - 5 7.2 18.4 0.36 10.9 5.8 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SEEEED PF14797.6 ORY96359.1 - 6.8 6.9 27.6 0.051 13.7 11.0 2.5 2 1 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Hid1 PF12722.7 ORY96359.1 - 9.5 4.2 15.9 14 3.7 15.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-W PF15510.6 ORY96360.1 - 1.9e-09 37.6 0.0 2.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein AAA_32 PF13654.6 ORY96360.1 - 0.016 14.0 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.23 ORY96360.1 - 0.06 13.6 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IZUMO PF15005.6 ORY96360.1 - 0.12 12.9 0.3 0.14 12.7 0.3 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated HEAT PF02985.22 ORY96361.1 - 4.8e-12 45.0 8.3 0.13 12.6 0.1 8.4 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 ORY96361.1 - 0.0011 19.3 3.9 0.13 12.6 0.0 5.3 5 2 2 7 7 7 2 HEAT repeats Cnd1 PF12717.7 ORY96361.1 - 0.0014 18.7 1.1 0.25 11.4 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY96361.1 - 0.016 15.8 1.2 58 4.4 0.0 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF3336 PF11815.8 ORY96362.1 - 2.4e-46 156.9 1.9 4.2e-46 156.1 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY96362.1 - 2.1e-16 60.7 0.2 1.4e-15 58.0 0.1 2.4 3 1 0 3 3 3 1 Patatin-like phospholipase CBM_14 PF01607.24 ORY96364.1 - 6.1e-09 35.9 0.1 1.1e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain SPT6_acidic PF14632.6 ORY96364.1 - 0.029 14.9 1.3 0.04 14.5 1.3 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 CBM_14 PF01607.24 ORY96365.1 - 7.7e-14 51.6 0.6 1.3e-13 50.9 0.6 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Atrophin-1 PF03154.15 ORY96365.1 - 0.65 8.2 7.9 0.72 8.1 7.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family tRNA-synt_1g PF09334.11 ORY96367.1 - 6.5e-82 275.4 0.2 1.6e-81 274.1 0.2 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY96367.1 - 1.5e-14 53.3 5.8 4.7e-11 41.7 0.1 3.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ORY96367.1 - 6.6e-06 25.7 0.0 0.004 16.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 ORY96367.1 - 0.00065 19.7 0.1 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DALR_1 PF05746.15 ORY96367.1 - 0.018 15.2 0.0 0.072 13.3 0.0 1.9 2 0 0 2 2 2 0 DALR anticodon binding domain tRNA-synt_1f PF01921.18 ORY96367.1 - 0.05 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Hira PF07569.11 ORY96367.1 - 0.14 11.9 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split tRNA-synt_1g PF09334.11 ORY96368.1 - 2.3e-16 59.5 0.6 2.7e-16 59.3 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY96368.1 - 8.1e-09 34.3 0.0 8.5e-09 34.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) NSP2-B_epitope PF14757.6 ORY96368.1 - 0.13 11.9 3.0 0.15 11.7 3.0 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein IMUP PF15761.5 ORY96368.1 - 1.1 10.0 6.4 1.5 9.6 6.4 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 ORY96368.1 - 1.8 8.1 7.9 2.2 7.9 7.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RasGEF PF00617.19 ORY96369.1 - 5.4e-15 56.0 1.0 1.2e-14 54.9 1.0 1.6 1 0 0 1 1 1 1 RasGEF domain PAM2 PF07145.15 ORY96369.1 - 0.0023 17.5 0.1 0.0064 16.1 0.1 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region G-patch PF01585.23 ORY96370.1 - 6e-12 45.3 1.5 1.1e-11 44.4 1.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY96370.1 - 0.042 13.9 0.6 0.13 12.3 0.6 1.8 1 0 0 1 1 1 0 G-patch domain Methyltransf_25 PF13649.6 ORY96372.1 - 1.7e-16 60.7 0.0 6.1e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96372.1 - 2.3e-14 53.6 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96372.1 - 8.6e-14 52.0 0.0 2.9e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96372.1 - 1.4e-11 44.4 0.0 8e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96372.1 - 4.5e-09 36.9 0.0 1.3e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY96372.1 - 3.2e-06 26.7 0.0 6.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY96372.1 - 0.0017 17.8 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 ORY96372.1 - 0.045 12.3 0.0 0.089 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 ORY96372.1 - 0.055 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Apt1 PF10351.9 ORY96372.1 - 3.4 6.4 8.3 4.9 5.9 8.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 ORY96373.1 - 5.6e-65 219.3 0.0 7.3e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96373.1 - 1.6e-33 116.1 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY96373.1 - 1.7e-07 30.9 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY96373.1 - 0.00062 18.6 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY96373.1 - 0.016 14.6 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORY96373.1 - 0.18 10.9 0.7 0.35 9.9 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Ank_2 PF12796.7 ORY96374.1 - 1e-21 77.3 0.1 2.2e-10 41.0 0.0 5.3 2 1 5 7 7 7 5 Ankyrin repeats (3 copies) VPS9 PF02204.18 ORY96374.1 - 7.9e-15 54.9 0.0 1.9e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_3 PF13606.6 ORY96374.1 - 1.4e-13 49.7 3.3 0.03 14.9 0.1 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 ORY96374.1 - 2e-12 47.4 2.5 3.6e-05 24.2 0.2 5.5 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY96374.1 - 8.9e-12 44.9 7.8 0.84 10.2 0.1 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 ORY96374.1 - 6.6e-07 29.5 2.8 0.014 15.7 0.0 6.0 4 1 2 6 6 6 1 Ankyrin repeats (many copies) PX PF00787.24 ORY96374.1 - 2.5e-06 27.4 0.0 7.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 PX domain DUF1216 PF06746.11 ORY96374.1 - 0.14 12.2 2.2 0.35 10.9 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) G-alpha PF00503.20 ORY96375.1 - 6.9e-118 393.9 0.8 8.7e-118 393.5 0.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY96375.1 - 1.7e-15 56.9 0.2 7.2e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ORY96375.1 - 0.00019 21.2 0.2 0.0018 18.1 0.1 2.3 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORY96375.1 - 0.00032 20.1 2.0 0.032 13.6 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORY96375.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY96375.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 ORY96375.1 - 0.15 12.2 1.2 2.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Rap_GAP PF02145.15 ORY96376.1 - 4.1e-54 183.0 0.0 6.3e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP PilX PF13681.6 ORY96376.1 - 0.0072 16.7 0.1 0.025 15.0 0.1 2.0 1 1 0 1 1 1 1 Type IV pilus assembly protein PilX C-term Ribonucleas_3_3 PF14622.6 ORY96377.1 - 1e-17 64.5 0.1 2.4e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 ORY96377.1 - 7.2e-10 39.4 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 ORY96377.1 - 8.4e-10 39.2 0.0 3.9e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease III domain MIR PF02815.19 ORY96378.1 - 2.5e-10 40.5 0.0 8.3e-10 38.8 0.0 1.7 1 1 1 2 2 2 1 MIR domain Ins145_P3_rec PF08709.11 ORY96378.1 - 0.0072 15.5 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor JmjC PF02373.22 ORY96379.1 - 1.5e-45 154.3 1.3 1.5e-45 154.3 1.3 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 ORY96379.1 - 8.1e-19 67.7 9.1 8.1e-19 67.7 9.1 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORY96379.1 - 1.6e-16 60.4 12.0 3.5e-16 59.3 12.0 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 ORY96379.1 - 1.2e-15 57.2 0.2 1.2e-15 57.2 0.2 2.0 2 0 0 2 2 2 1 jmjN domain EOS1 PF12326.8 ORY96379.1 - 2 8.3 6.8 0.67 9.9 2.3 2.3 2 1 0 2 2 2 0 N-glycosylation protein Nucleopor_Nup85 PF07575.13 ORY96380.1 - 1.3e-49 169.3 0.2 1.8e-49 168.8 0.2 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin WD40 PF00400.32 ORY96382.1 - 4e-05 24.3 1.0 0.057 14.3 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96382.1 - 0.0034 17.7 0.0 43 4.5 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY96382.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GDC-P PF02347.16 ORY96383.1 - 2.3e-203 675.9 1.3 1.4e-191 637.0 0.6 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 ORY96383.1 - 1.3e-06 27.9 4.5 8.6e-06 25.2 0.2 2.7 3 0 0 3 3 3 2 Beta-eliminating lyase DUF4332 PF14229.6 ORY96383.1 - 0.18 12.0 0.4 0.71 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) HATPase_c_3 PF13589.6 ORY96384.1 - 3.1e-13 49.7 0.1 6.7e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 ORY96384.1 - 9.4e-13 48.2 0.1 3.5e-11 43.1 0.2 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 ORY96384.1 - 1.8e-08 34.8 0.0 3.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 ORY96384.1 - 0.00068 19.3 0.0 0.003 17.2 0.0 2.1 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Aa_trans PF01490.18 ORY96385.1 - 3.6e-79 266.4 28.7 4.3e-79 266.1 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3808 PF10300.9 ORY96386.1 - 6.7e-70 236.1 5.4 9.4e-70 235.7 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) SIS PF01380.22 ORY96388.1 - 4.4e-67 223.9 0.2 1.4e-34 118.7 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORY96388.1 - 1.6e-17 63.9 0.0 3.8e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY96388.1 - 9.4e-14 51.4 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY96388.1 - 0.00031 19.7 0.0 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ORY96388.1 - 0.14 12.2 0.0 0.45 10.5 0.0 2.0 1 0 0 1 1 1 0 SIS domain SelR PF01641.18 ORY96389.1 - 7.8e-53 177.7 0.1 9.4e-53 177.4 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 ORY96389.1 - 0.017 15.3 0.4 0.035 14.3 0.4 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 ORY96389.1 - 0.032 14.0 0.5 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TPR_12 PF13424.6 ORY96390.1 - 2.2e-15 56.7 13.6 1.8e-05 24.9 1.2 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY96390.1 - 1.8e-13 49.7 9.0 0.047 13.5 3.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96390.1 - 1.8e-12 46.3 13.6 0.099 12.8 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY96390.1 - 4.8e-11 42.0 7.0 0.014 15.6 1.3 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY96390.1 - 1.3e-08 34.4 11.4 0.031 14.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY96390.1 - 2.6e-06 27.1 4.8 0.0015 18.0 0.1 2.9 2 2 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 ORY96390.1 - 1.2e-05 25.0 9.1 3 8.1 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat FlgN PF05130.12 ORY96390.1 - 0.036 14.6 0.7 1.7 9.2 0.0 2.8 2 1 0 2 2 2 0 FlgN protein TPR_16 PF13432.6 ORY96390.1 - 0.065 13.9 8.1 4.5 8.0 0.2 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY96390.1 - 0.62 10.6 4.1 27 5.4 0.0 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96390.1 - 1.9 9.6 14.6 5.8 8.0 0.4 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY96390.1 - 4.5 8.1 6.0 87 4.1 0.2 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2834 PF11196.8 ORY96391.1 - 9.5e-13 48.3 27.4 5.8e-07 29.8 5.2 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) NAD_Gly3P_dh_N PF01210.23 ORY96392.1 - 7.4e-49 165.7 0.0 1.2e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORY96392.1 - 8.6e-47 159.0 0.2 1.4e-46 158.3 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 ORY96392.1 - 0.0074 16.8 0.0 3.3 8.3 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent PAS PF00989.25 ORY96392.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold F-box PF00646.33 ORY96393.1 - 0.037 13.9 0.1 0.097 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain Malic_M PF03949.15 ORY96394.1 - 3e-88 295.4 0.1 3.9e-88 295.1 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORY96394.1 - 4e-58 196.2 0.0 7.4e-58 195.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pex14_N PF04695.13 ORY96395.1 - 0.007 17.0 0.8 0.011 16.5 0.8 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SH2_2 PF14633.6 ORY96396.1 - 8.5e-67 224.7 0.0 1.9e-64 217.0 0.0 2.6 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 ORY96396.1 - 2e-31 108.8 0.0 4e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 ORY96396.1 - 4.2e-30 104.2 0.0 2.3e-29 101.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.6 ORY96396.1 - 6.4e-26 91.1 0.1 1.7e-25 89.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 ORY96396.1 - 2.5e-19 69.7 26.0 2.5e-19 69.7 26.0 4.3 4 0 0 4 4 3 1 Acidic N-terminal SPT6 SH2 PF00017.24 ORY96396.1 - 1e-07 31.9 0.0 2.4e-06 27.6 0.0 2.9 3 0 0 3 3 3 1 SH2 domain HHH_9 PF17674.1 ORY96396.1 - 0.00029 21.7 0.9 0.0025 18.7 0.7 2.9 2 1 0 2 2 1 1 HHH domain Tex_YqgF PF16921.5 ORY96396.1 - 0.00096 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain S1 PF00575.23 ORY96396.1 - 0.0042 17.4 0.1 0.012 15.9 0.1 1.9 1 0 0 1 1 1 1 S1 RNA binding domain Tex_N PF09371.10 ORY96396.1 - 0.014 15.1 0.2 0.058 13.1 0.0 2.2 2 0 0 2 2 2 0 Tex-like protein N-terminal domain HHH_3 PF12836.7 ORY96396.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sugar_tr PF00083.24 ORY96397.1 - 1.5e-112 376.7 18.3 1.9e-112 376.4 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY96397.1 - 7e-24 84.4 32.2 1.1e-15 57.4 9.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 ORY96397.1 - 0.2 12.2 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 ORY96398.1 - 2.6e-21 76.1 0.1 1.5e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY96398.1 - 5.1e-20 72.0 0.0 2.1e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96398.1 - 2.9e-19 69.4 0.0 4.3e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96398.1 - 1e-18 67.9 0.1 3.3e-18 66.2 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96398.1 - 8.3e-18 64.8 0.0 1.7e-17 63.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY96398.1 - 4.2e-11 42.3 0.0 5.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ORY96398.1 - 5.5e-09 35.8 0.0 8.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 ORY96398.1 - 3.7e-07 29.7 0.0 9.5e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ORY96398.1 - 9e-07 28.4 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 ORY96398.1 - 1.7e-06 27.8 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 ORY96398.1 - 8.5e-06 25.0 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 ORY96398.1 - 2.9e-05 24.1 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORY96398.1 - 0.00016 20.9 0.0 0.0008 18.6 0.0 1.9 2 0 0 2 2 2 1 DREV methyltransferase TPMT PF05724.11 ORY96398.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 ORY96398.1 - 0.00062 19.2 0.0 0.00091 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 ORY96398.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Cons_hypoth95 PF03602.15 ORY96398.1 - 0.0073 16.0 0.0 0.016 14.8 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 TehB PF03848.14 ORY96398.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB N6_N4_Mtase PF01555.18 ORY96398.1 - 0.032 13.9 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 DNA methylase PCMT PF01135.19 ORY96398.1 - 0.039 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 ORY96398.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 UBX PF00789.20 ORY96399.1 - 1.8e-13 50.4 0.0 3.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF4746 PF15928.5 ORY96399.1 - 0.14 11.6 6.2 0.33 10.3 6.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Hid1 PF12722.7 ORY96399.1 - 1.5 6.9 5.8 0.11 10.6 1.0 1.5 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 ORY96399.1 - 2.9 6.6 5.2 0.24 10.1 0.7 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein LSM PF01423.22 ORY96400.1 - 4.1e-17 61.6 1.0 6.2e-17 61.0 1.0 1.3 1 1 0 1 1 1 1 LSM domain PliI PF16743.5 ORY96400.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Periplasmic lysozyme inhibitor of I-type lysozyme CDP-OH_P_transf PF01066.21 ORY96401.1 - 7.8e-13 49.0 0.7 7.8e-13 49.0 0.7 2.2 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PH PF00169.29 ORY96402.1 - 6.4e-06 26.6 0.7 2.5e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 PH domain Ldh_1_C PF02866.18 ORY96402.1 - 0.83 9.6 2.8 3.7 7.4 2.1 2.2 1 1 1 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain adh_short_C2 PF13561.6 ORY96403.1 - 1.3e-51 175.4 0.0 1.6e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY96403.1 - 1.4e-44 151.9 0.2 1.8e-44 151.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY96403.1 - 1.2e-10 41.7 0.2 1.5e-10 41.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY96403.1 - 0.00028 20.1 0.5 0.00034 19.8 0.5 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SAM_2 PF07647.17 ORY96404.1 - 1.1e-08 35.1 0.3 6.9e-08 32.5 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY96404.1 - 8.9e-08 32.5 0.2 1.9e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 ORY96404.1 - 0.017 15.4 0.1 0.046 14.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) SelP_N PF04592.14 ORY96404.1 - 6.4 6.1 20.1 13 5.1 20.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_S10 PF00450.22 ORY96405.1 - 4.6e-106 355.7 0.3 5.8e-106 355.4 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Isy1 PF06246.12 ORY96406.1 - 1.5e-86 290.1 8.0 1e-85 287.4 8.0 1.8 1 1 0 1 1 1 1 Isy1-like splicing family Choline_transpo PF04515.12 ORY96407.1 - 3.1e-57 194.2 22.9 3.1e-57 194.2 22.9 2.2 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF2749 PF10907.8 ORY96407.1 - 0.079 13.1 0.8 3.2 8.0 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Utp13 PF08625.11 ORY96407.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain PX PF00787.24 ORY96408.1 - 1.9e-24 85.8 1.5 5e-24 84.5 0.9 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY96408.1 - 1.9e-08 34.2 7.9 1.8e-07 30.9 1.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Snapin_Pallidin PF14712.6 ORY96408.1 - 0.03 14.7 3.6 0.27 11.7 0.3 2.8 2 0 0 2 2 2 0 Snapin/Pallidin ECH_2 PF16113.5 ORY96408.1 - 0.06 12.8 0.2 0.06 12.8 0.2 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF1664 PF07889.12 ORY96408.1 - 0.068 13.2 3.4 1.4 9.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lipase_chap PF03280.14 ORY96408.1 - 0.072 13.0 0.3 0.072 13.0 0.3 2.3 2 1 0 2 2 2 0 Proteobacterial lipase chaperone protein DIT1_PvcA PF05141.12 ORY96408.1 - 0.11 11.9 3.7 1.6 8.1 3.7 2.4 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Occludin_ELL PF07303.13 ORY96408.1 - 0.13 13.0 0.1 0.13 13.0 0.1 2.9 2 1 1 3 3 3 0 Occludin homology domain BAR_3 PF16746.5 ORY96408.1 - 0.34 10.6 6.1 0.28 10.9 2.1 2.5 1 1 1 2 2 2 0 BAR domain of APPL family DUF16 PF01519.16 ORY96408.1 - 0.8 10.2 3.7 7.1 7.2 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 Phage_TAC_8 PF10666.9 ORY96408.1 - 1.1 9.5 5.0 1.3 9.3 0.3 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 BAR PF03114.18 ORY96408.1 - 1.1 8.8 8.5 0.46 10.1 0.4 2.9 2 1 1 3 3 3 0 BAR domain ETC_C1_NDUFA5 PF04716.14 ORY96409.1 - 1.7e-27 95.0 0.2 2.6e-27 94.4 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Indigoidine_A PF04227.12 ORY96410.1 - 4.7e-132 439.7 7.7 5.4e-132 439.5 7.7 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein TPP_enzyme_N PF02776.18 ORY96410.1 - 0.022 14.3 0.2 0.022 14.3 0.2 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF768 PF05589.11 ORY96410.1 - 0.049 13.7 0.5 0.12 12.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) C2 PF00168.30 ORY96411.1 - 5.3e-13 49.2 0.0 7.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain B9-C2 PF07162.11 ORY96411.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein DUF4497 PF14924.6 ORY96411.1 - 0.052 14.0 0.0 3.9 8.0 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4497) zf-H2C2_2 PF13465.6 ORY96412.1 - 8e-06 26.1 23.4 1.5e-05 25.2 0.3 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY96412.1 - 0.00029 21.4 23.9 0.029 15.2 0.5 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY96412.1 - 0.0031 17.9 0.4 0.0031 17.9 0.4 3.5 3 1 1 4 4 4 2 Zinc finger, C2H2 type Spt46 PF17734.1 ORY96412.1 - 0.043 13.6 4.3 0.051 13.4 3.7 1.5 1 1 0 1 1 1 0 Spermatogenesis-associated protein 46 zf-C2H2_6 PF13912.6 ORY96412.1 - 0.072 13.1 2.6 0.072 13.1 2.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Xpo1 PF08389.12 ORY96414.1 - 2.7e-08 34.0 4.9 8.3e-07 29.2 0.4 3.8 3 1 0 3 3 3 1 Exportin 1-like protein SafA PF17073.5 ORY96414.1 - 0.22 11.5 1.1 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Two-component-system connector protein Acetyltransf_1 PF00583.25 ORY96415.1 - 5.4e-15 55.6 0.0 7.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY96415.1 - 1.1e-09 38.3 0.1 1.3e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY96415.1 - 2.4e-07 31.1 0.0 3.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY96415.1 - 2.3e-06 27.5 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY96415.1 - 9.7e-05 22.5 0.2 0.00017 21.7 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY96415.1 - 0.00059 19.4 1.1 0.00099 18.6 0.1 1.8 1 1 1 2 2 2 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 ORY96415.1 - 0.033 14.9 0.0 0.052 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 ORY96415.1 - 0.06 13.1 0.1 0.081 12.7 0.1 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ EnY2 PF10163.9 ORY96416.1 - 6.3e-21 74.5 0.1 7.3e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 TFIIE_beta PF02186.15 ORY96416.1 - 0.11 12.8 0.2 1.2 9.5 0.1 2.0 2 0 0 2 2 2 0 TFIIE beta subunit core domain Rer1 PF03248.13 ORY96417.1 - 2e-81 271.8 8.1 2.3e-81 271.6 8.1 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 ORY96417.1 - 2.4 7.7 9.4 0.2 11.2 2.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Peptidase_C14 PF00656.22 ORY96418.1 - 2.3e-66 224.3 0.0 3.1e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF3730 PF12530.8 ORY96418.1 - 0.04 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Fungal_trans PF04082.18 ORY96419.1 - 6.7e-28 97.4 0.1 3.2e-26 91.9 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 ORY96420.1 - 1.5e-13 50.4 26.1 1.7e-13 50.2 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY96420.1 - 6.6e-08 31.6 17.2 1.1e-07 30.9 17.2 1.3 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 ORY96420.1 - 1.7 7.8 13.1 3.5 6.8 12.6 1.6 1 1 0 1 1 1 0 Sodium:alanine symporter family AA_permease_2 PF13520.6 ORY96421.1 - 1.4e-35 123.0 24.1 1.6e-35 122.8 24.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1129 PF06570.11 ORY96421.1 - 5.9 6.3 13.1 2.1 7.8 7.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Myb_DNA-binding PF00249.31 ORY96423.1 - 2.2e-05 24.5 0.1 5.4e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY96423.1 - 0.0073 16.5 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain RestrictionMunI PF11407.8 ORY96423.1 - 0.07 12.8 0.7 1.4 8.6 0.7 2.2 1 1 0 1 1 1 0 Type II restriction enzyme MunI AICARFT_IMPCHas PF01808.18 ORY96424.1 - 1.1e-98 330.4 0.5 1.9e-98 329.6 0.5 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ORY96424.1 - 1.4e-24 86.1 0.0 3.4e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain EF-hand_1 PF00036.32 ORY96425.1 - 2.5e-23 79.8 17.1 4.4e-06 25.9 1.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY96425.1 - 2.1e-20 73.0 7.6 9.6e-12 45.2 1.5 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY96425.1 - 2.4e-18 64.4 10.7 5.2e-05 22.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORY96425.1 - 4.1e-15 54.5 17.6 4.7e-05 22.7 0.8 4.6 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 ORY96425.1 - 2.3e-10 40.2 16.3 0.0044 16.8 1.0 4.3 2 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY96425.1 - 1.3e-06 28.7 0.3 0.012 16.0 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY96425.1 - 0.00041 20.3 10.0 0.033 14.2 1.1 3.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY96425.1 - 0.02 15.2 0.2 2.7 8.4 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain Nse4-Nse3_bdg PF15412.6 ORY96425.1 - 1.2 9.3 5.8 6.4 7.0 0.6 3.4 3 1 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE Terminase_6C PF17289.2 ORY96427.1 - 0.011 15.9 0.0 0.71 10.0 0.0 2.2 1 1 0 2 2 2 0 Terminase RNaseH-like domain RNA_pol_3_Rpc31 PF11705.8 ORY96427.1 - 0.096 12.9 9.3 0.13 12.5 9.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 ORY96427.1 - 3.9 6.7 9.0 5.7 6.2 9.0 1.3 1 0 0 1 1 1 0 BUD22 PAP2_3 PF14378.6 ORY96428.1 - 4.5e-24 85.2 7.2 8.9e-24 84.2 7.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 ORY96428.1 - 5.5e-09 35.9 6.3 5.5e-09 35.9 6.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily Asp PF00026.23 ORY96429.1 - 8.1e-71 239.0 0.0 1e-70 238.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY96429.1 - 1.2e-05 25.6 0.4 0.0013 19.0 0.4 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY96429.1 - 0.00053 20.6 1.3 0.076 13.7 0.4 3.2 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 ORY96429.1 - 0.00068 19.5 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ORY96429.1 - 0.053 14.1 0.7 0.42 11.2 0.2 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease ABC2_membrane PF01061.24 ORY96430.1 - 6e-85 283.9 55.2 3.5e-46 157.3 22.5 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ORY96430.1 - 1.8e-36 125.6 0.0 3e-19 69.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY96430.1 - 2.4e-29 101.1 4.1 1.9e-24 85.4 0.1 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY96430.1 - 6.3e-08 33.1 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORY96430.1 - 2.8e-06 26.7 51.1 0.0022 17.2 19.3 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORY96430.1 - 6.4e-05 22.9 0.0 0.004 17.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 ORY96430.1 - 0.00018 21.5 0.0 0.72 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY96430.1 - 0.00086 19.7 0.0 0.046 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ORY96430.1 - 0.0024 17.6 0.5 0.021 14.5 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY96430.1 - 0.0038 17.8 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORY96430.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY96430.1 - 0.038 13.7 0.2 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORY96430.1 - 0.045 13.7 0.1 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 ORY96430.1 - 0.11 12.6 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY96430.1 - 0.12 11.9 0.5 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 ORY96430.1 - 0.15 10.7 0.1 16 4.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ORY96430.1 - 0.15 12.4 1.1 2 8.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY96430.1 - 0.21 11.7 0.4 11 6.2 0.1 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF3824 PF12868.7 ORY96431.1 - 7.3 7.2 7.1 21 5.7 0.6 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Pkinase PF00069.25 ORY96432.1 - 3.6e-58 197.0 0.0 5e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96432.1 - 7.5e-23 81.1 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY96432.1 - 1.3e-08 34.6 0.0 2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAS PF00989.25 ORY96432.1 - 1.5e-07 31.4 0.0 0.032 14.2 0.0 3.5 4 1 1 5 5 5 2 PAS fold PAS_9 PF13426.7 ORY96432.1 - 3.9e-06 27.0 0.0 0.046 14.0 0.0 3.8 3 1 0 3 3 3 2 PAS domain PAS_8 PF13188.7 ORY96432.1 - 4.9e-05 23.2 0.0 0.0022 17.9 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORY96432.1 - 6.6e-05 23.1 0.0 0.52 10.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold RIO1 PF01163.22 ORY96432.1 - 0.00017 21.2 0.2 0.00031 20.4 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY96432.1 - 0.00035 20.0 0.2 0.00062 19.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY96432.1 - 0.00046 20.2 0.9 0.0055 16.6 0.6 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY96432.1 - 0.0011 17.9 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY96432.1 - 0.0031 16.5 0.1 0.0046 15.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PAS_3 PF08447.12 ORY96432.1 - 0.029 14.7 0.0 0.32 11.3 0.0 2.5 2 0 0 2 2 2 0 PAS fold FTA2 PF13095.6 ORY96432.1 - 0.042 13.5 0.2 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TMEM70 PF06979.12 ORY96433.1 - 4.9e-08 33.5 1.8 1.2e-07 32.3 1.8 1.7 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Pantoate_ligase PF02569.15 ORY96434.1 - 1.7e-99 332.3 0.0 2e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase USP7_ICP0_bdg PF12436.8 ORY96435.1 - 4.2e-69 232.5 0.5 1.7e-66 223.9 0.0 3.8 4 1 0 4 4 4 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 ORY96435.1 - 1.1e-61 208.2 0.5 1.5e-59 201.2 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 ORY96435.1 - 2.5e-48 164.8 0.2 4.4e-48 164.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY96435.1 - 6.1e-22 78.6 0.0 1.5e-21 77.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORY96435.1 - 8.7e-09 35.5 0.0 3.2e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 MATH domain PGA2 PF07543.12 ORY96436.1 - 0.073 13.0 0.6 1.9 8.5 0.0 2.7 2 1 1 3 3 3 0 Protein trafficking PGA2 Mpp10 PF04006.12 ORY96437.1 - 2.8e-147 491.8 78.6 3.2e-147 491.6 78.6 1.0 1 0 0 1 1 1 1 Mpp10 protein DASH_Dam1 PF08653.10 ORY96439.1 - 0.55 10.1 2.5 1.9 8.4 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 CCDC92 PF14916.6 ORY96439.1 - 0.63 9.9 9.3 1.6 8.5 1.5 3.4 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DehI PF10778.9 ORY96439.1 - 0.79 9.9 5.2 0.89 9.7 0.4 2.5 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI DUF4047 PF13256.6 ORY96439.1 - 0.99 9.6 8.4 0.058 13.6 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) CDPS PF16715.5 ORY96439.1 - 3.3 7.3 12.7 0.38 10.4 5.0 2.4 2 0 0 2 2 2 0 Cyclodipeptide synthase zf-Tim10_DDP PF02953.15 ORY96440.1 - 1.1e-21 76.2 3.4 1.5e-21 75.8 3.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 ORY96440.1 - 0.021 14.5 3.5 0.027 14.2 3.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Baculo_gp41 PF04700.12 ORY96440.1 - 0.038 13.8 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region zf-C2HCIx2C PF10782.9 ORY96440.1 - 0.056 13.4 4.0 0.24 11.4 4.0 1.9 1 1 0 1 1 1 0 Zinc-finger Enolase_C PF00113.22 ORY96441.1 - 2.3e-154 513.0 0.1 2.9e-154 512.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORY96441.1 - 3.2e-57 192.3 0.1 6.9e-57 191.2 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORY96441.1 - 0.00047 19.8 0.0 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORY96441.1 - 0.0061 15.7 0.3 0.013 14.6 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus ERG4_ERG24 PF01222.17 ORY96442.1 - 1.3e-143 478.9 6.6 1.4e-143 478.7 6.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY96442.1 - 0.00046 19.8 0.2 0.0011 18.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY96442.1 - 0.11 12.9 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CoxIIa PF08113.11 ORY96442.1 - 0.46 10.3 5.8 0.24 11.3 2.4 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family CN_hydrolase PF00795.22 ORY96443.1 - 1.2e-62 211.6 0.0 1.4e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_6 PF13964.6 ORY96443.1 - 0.02 15.2 0.6 0.12 12.7 0.1 2.6 3 1 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 ORY96443.1 - 0.048 13.7 0.2 0.67 10.0 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY96443.1 - 0.051 13.6 0.2 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Kelch motif Fanconi_A_N PF15865.5 ORY96444.1 - 4.5e-05 23.0 0.0 6.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fanconi anaemia group A protein N terminus Ribosomal_L32e PF01655.18 ORY96445.1 - 4.9e-50 168.5 0.5 5.8e-50 168.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 FHA PF00498.26 ORY96446.1 - 4.6e-15 55.7 0.0 1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY96446.1 - 7.3e-11 41.6 11.3 1.4e-10 40.8 11.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY96446.1 - 3.4e-07 30.5 10.9 5.4e-07 29.9 10.9 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 ORY96446.1 - 0.0014 18.9 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 ORY96446.1 - 0.0015 18.3 12.3 0.0026 17.6 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY96446.1 - 0.0038 17.5 8.1 0.0085 16.4 8.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY96446.1 - 0.0078 16.1 10.5 0.013 15.3 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY96446.1 - 0.044 13.7 6.2 0.073 13.0 6.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 ORY96446.1 - 0.093 12.7 9.6 0.17 11.9 9.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY96446.1 - 0.22 11.6 2.6 0.4 10.8 2.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY96446.1 - 3 7.9 13.5 6.4 6.9 13.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger ANF_receptor PF01094.28 ORY96447.1 - 1.2e-31 110.2 0.1 2.6e-31 109.0 0.0 1.6 2 0 0 2 2 2 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY96447.1 - 1.7e-28 100.0 21.9 1.7e-28 100.0 21.9 1.7 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Alba PF01918.21 ORY96448.1 - 6.7e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Alba PAM2 PF07145.15 ORY96448.1 - 0.00059 19.3 3.1 0.45 10.3 0.2 2.4 1 1 1 2 2 2 2 Ataxin-2 C-terminal region POX PF07526.11 ORY96448.1 - 0.0013 19.3 1.8 0.0025 18.4 1.8 1.6 1 1 0 1 1 1 1 Associated with HOX Presenilin PF01080.17 ORY96448.1 - 0.005 15.7 7.2 0.0056 15.5 7.2 1.1 1 0 0 1 1 1 1 Presenilin Ring_hydroxyl_A PF00848.19 ORY96448.1 - 0.03 14.3 2.2 0.04 13.9 2.2 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Ndc1_Nup PF09531.10 ORY96448.1 - 0.085 11.5 8.8 0.086 11.5 8.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 ORY96448.1 - 0.12 12.4 20.2 0.14 12.1 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 ORY96448.1 - 0.16 10.8 6.2 0.16 10.8 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Suf PF05843.14 ORY96448.1 - 0.22 11.5 17.8 0.3 11.0 17.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Joubert PF15392.6 ORY96448.1 - 0.25 11.0 13.8 0.33 10.6 13.8 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated Zip PF02535.22 ORY96448.1 - 0.51 9.5 2.8 0.48 9.6 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SKA1 PF07160.12 ORY96448.1 - 2.6 7.8 13.8 3.8 7.3 13.8 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Endostatin PF06482.11 ORY96448.1 - 2.9 7.3 11.7 3.8 6.9 11.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 ORY96448.1 - 3.9 7.2 14.2 5.3 6.8 14.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 ORY96448.1 - 5.5 5.1 20.1 6.4 4.9 20.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 ORY96448.1 - 5.5 7.0 8.8 7.6 6.5 8.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.13 ORY96448.1 - 5.9 5.1 8.7 7 4.9 8.7 1.1 1 0 0 1 1 1 0 Menin Pannexin_like PF12534.8 ORY96448.1 - 6.4 5.8 6.7 8.7 5.3 6.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF416 PF04222.12 ORY96449.1 - 0.2 11.1 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF416) DPPIV_N PF00930.21 ORY96450.1 - 7.9e-98 327.5 9.5 1e-97 327.1 9.5 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORY96450.1 - 2.3e-51 174.3 1.5 4e-51 173.5 1.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY96450.1 - 0.0093 15.6 3.0 0.029 14.0 1.5 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 ORY96450.1 - 0.037 13.8 0.1 0.97 9.2 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mito_carr PF00153.27 ORY96451.1 - 7.4e-42 141.2 8.4 3.8e-16 58.8 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein E1_dh PF00676.20 ORY96452.1 - 1.7e-63 214.4 0.0 2.2e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 ORY96452.1 - 1.4e-61 207.3 0.0 2.1e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORY96452.1 - 1.2e-55 187.4 0.0 2.2e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 ORY96452.1 - 2.6e-20 71.7 0.2 6.1e-20 70.5 0.2 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PFOR_II PF17147.4 ORY96452.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Cation_efflux PF01545.21 ORY96453.1 - 1.4e-47 162.1 4.9 1.7e-47 161.7 4.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY96453.1 - 0.00071 19.7 0.3 0.0014 18.7 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter 2OG-FeII_Oxy PF03171.20 ORY96454.1 - 1.1e-20 74.0 0.0 2.8e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY96454.1 - 1.8e-20 73.9 0.1 3.4e-20 72.9 0.1 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RNase_H PF00075.24 ORY96455.1 - 6.9e-19 68.4 0.0 3.1e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 ORY96455.1 - 9.4e-05 22.2 0.1 0.00023 21.0 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like WxL PF13731.6 ORY96456.1 - 0.0017 18.4 6.1 0.0018 18.3 6.1 1.2 1 0 0 1 1 1 1 WxL domain surface cell wall-binding Amelin PF05111.12 ORY96456.1 - 0.019 14.2 7.1 0.025 13.7 7.1 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) DUF3292 PF11696.8 ORY96456.1 - 0.098 11.0 5.9 0.11 10.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SPG4 PF17325.2 ORY96456.1 - 0.11 13.6 3.7 0.16 13.1 3.7 1.3 1 0 0 1 1 1 0 Stationary phase protein 4 EIIBC-GUT_N PF03612.14 ORY96456.1 - 0.3 10.8 3.3 0.35 10.6 3.3 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FlaG PF03646.15 ORY96456.1 - 0.37 11.0 13.0 0.21 11.7 11.0 1.7 1 1 1 2 2 2 0 FlaG protein SprA-related PF12118.8 ORY96456.1 - 0.42 9.7 19.2 0.48 9.5 19.2 1.1 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 ORY96456.1 - 0.43 10.5 21.4 0.49 10.3 21.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 ORY96456.1 - 0.44 10.2 3.7 0.54 9.9 3.7 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Nuc_deoxyri_tr2 PF15891.5 ORY96456.1 - 0.64 10.4 7.8 2.1 8.7 0.1 2.2 1 1 1 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Androgen_recep PF02166.16 ORY96456.1 - 0.96 8.2 13.8 1.2 7.9 13.8 1.2 1 0 0 1 1 1 0 Androgen receptor Suf PF05843.14 ORY96456.1 - 1.4 8.9 13.3 1.7 8.6 13.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 ORY96456.1 - 2.1 7.2 26.8 2.2 7.1 26.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.8 ORY96456.1 - 2.3 7.3 20.0 2.9 7.0 20.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Presenilin PF01080.17 ORY96456.1 - 6.7 5.4 9.8 6.4 5.4 9.8 1.1 1 0 0 1 1 1 0 Presenilin NIBRIN_BRCT_II PF16508.5 ORY96457.1 - 2e-05 24.9 0.0 2.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein BRCT_2 PF16589.5 ORY96457.1 - 3.7e-05 24.0 0.0 5.4e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY96457.1 - 0.00017 21.9 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Arrestin_N PF00339.29 ORY96458.1 - 1e-08 35.3 0.3 2.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORY96458.1 - 0.12 11.6 0.1 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Rgp1 DUF3340 PF11818.8 ORY96460.1 - 0.22 11.6 0.0 0.29 11.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Glyco_transf_41 PF13844.6 ORY96461.1 - 1.1e-112 377.0 8.0 5.4e-56 190.0 0.0 3.7 3 1 1 4 4 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 ORY96461.1 - 2.1e-18 65.3 1.0 0.0027 17.4 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96461.1 - 1.4e-15 56.1 0.5 0.065 13.4 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY96461.1 - 7.5e-14 51.1 1.3 0.0018 17.9 0.0 7.1 4 2 3 7 7 7 4 TPR repeat TPR_8 PF13181.6 ORY96461.1 - 1.2e-13 50.1 0.1 0.00013 21.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY96461.1 - 4.1e-13 48.7 2.4 0.012 16.0 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY96461.1 - 4.9e-13 48.5 9.3 0.0028 17.5 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY96461.1 - 4.8e-10 39.6 7.9 0.018 15.4 0.0 6.1 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY96461.1 - 3.7e-05 23.4 0.0 4 7.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat RskA PF10099.9 ORY96461.1 - 0.0001 22.6 41.2 0.097 13.0 2.3 4.7 3 1 1 4 4 4 3 Anti-sigma-K factor rskA TPR_9 PF13371.6 ORY96461.1 - 0.0002 21.4 1.2 0.037 14.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96461.1 - 0.23 12.4 11.9 26 6.0 0.0 6.5 6 1 1 7 7 4 0 Tetratricopeptide repeat SLATT_1 PF18181.1 ORY96461.1 - 4.5 7.2 10.4 0.67 9.9 1.4 3.9 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 GREB1 PF15782.5 ORY96462.1 - 2 5.4 19.0 2.8 4.9 19.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3519 PF12033.8 ORY96462.1 - 2.7 8.4 7.5 0.17 12.3 1.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3519) adh_short_C2 PF13561.6 ORY96463.1 - 4.7e-70 235.8 0.5 5.4e-70 235.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY96463.1 - 2.1e-50 170.9 0.6 2.5e-50 170.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY96463.1 - 2.1e-06 27.7 1.0 3.3e-06 27.1 1.0 1.2 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.14 ORY96463.1 - 0.045 13.3 0.2 0.069 12.7 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Metallophos PF00149.28 ORY96464.1 - 1.1e-38 133.8 0.1 1.4e-38 133.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY96464.1 - 6.9e-17 61.6 0.2 1.7e-16 60.4 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PH PF00169.29 ORY96465.1 - 1.5e-10 41.5 0.0 2.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 PH domain NigD_N PF12667.7 ORY96465.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 NigD-like N-terminal OB domain DotU PF09850.9 ORY96466.1 - 0.031 14.0 1.9 0.064 13.0 1.9 1.5 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF2207 PF09972.9 ORY96466.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Homeodomain PF00046.29 ORY96467.1 - 1.1e-19 70.1 1.0 1.1e-19 70.1 1.0 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY96467.1 - 0.15 12.0 0.2 0.15 12.0 0.2 3.1 4 0 0 4 4 4 0 Homeobox KN domain Myb_DNA-binding PF00249.31 ORY96468.1 - 4.2e-56 186.9 14.6 5.4e-14 52.1 0.1 5.8 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY96468.1 - 2.1e-46 156.0 23.4 2.5e-14 53.2 0.0 5.6 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 ORY96468.1 - 4.2e-08 33.2 9.2 0.0034 17.4 0.0 4.9 2 1 3 6 6 6 2 SLIDE Myb_DNA-bind_7 PF15963.5 ORY96468.1 - 9.9e-08 31.8 6.9 0.37 10.7 0.0 5.1 3 1 2 5 5 5 3 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORY96468.1 - 2.2e-06 27.8 7.9 0.1 12.8 0.4 4.7 1 1 3 4 4 4 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 ORY96468.1 - 0.00045 20.3 0.0 0.16 12.1 0.2 3.4 2 2 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 ORY96468.1 - 0.62 10.4 9.1 4.2 7.8 0.6 4.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PIN_4 PF13638.6 ORY96469.1 - 1.7e-16 60.7 0.1 2.2e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 ORY96469.1 - 0.0027 18.2 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 ORY96469.1 - 0.0041 17.4 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 PIN like domain DAZAP2 PF11029.8 ORY96470.1 - 0.39 11.6 3.6 0.33 11.9 0.9 2.2 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) DUF1682 PF07946.14 ORY96470.1 - 0.52 9.5 6.4 1 8.5 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Y_phosphatase PF00102.27 ORY96471.1 - 2.7e-69 233.3 1.2 5.1e-69 232.4 1.2 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 ORY96471.1 - 2.8e-10 40.6 0.0 9.4e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 ORY96471.1 - 0.012 15.6 0.0 0.037 14.0 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 ORY96471.1 - 0.013 15.3 1.1 0.029 14.2 0.1 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Gastrin PF00918.17 ORY96471.1 - 0.023 15.7 1.4 0.56 11.2 0.0 2.7 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DUF2374 PF09574.10 ORY96471.1 - 1.2 9.0 2.7 2.3 8.1 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) DUF3275 PF11679.8 ORY96473.1 - 0.024 14.6 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MULE PF10551.9 ORY96475.1 - 0.0044 17.4 0.0 0.0052 17.2 0.0 1.1 1 0 0 1 1 1 1 MULE transposase domain Asp PF00026.23 ORY96476.1 - 1.3e-69 235.1 3.4 1.5e-69 234.8 3.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY96476.1 - 4.2e-12 46.7 6.5 1.1e-08 35.6 0.2 3.4 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Peroxin-22 PF12827.7 ORY96477.1 - 0.0058 16.5 0.1 0.0093 15.9 0.1 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family Ribosomal_S2 PF00318.20 ORY96478.1 - 2.3e-63 213.3 0.1 2.3e-36 125.1 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S2 LDcluster4 PF18306.1 ORY96478.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 SLOG cluster4 family Ribosomal_L15e PF00827.17 ORY96479.1 - 8.9e-89 296.3 9.6 1e-88 296.1 9.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 WLM PF08325.10 ORY96480.1 - 6.8e-44 150.2 0.2 8.9e-44 149.8 0.2 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 ORY96480.1 - 0.012 15.6 1.3 0.016 15.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 SPOR PF05036.13 ORY96480.1 - 0.028 14.8 0.6 0.058 13.8 0.0 1.8 2 1 0 2 2 2 0 Sporulation related domain MHCassoc_trimer PF08831.10 ORY96480.1 - 0.097 12.7 0.3 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Glyco_hydro_38N PF01074.22 ORY96481.1 - 1.1e-84 284.3 0.7 2.3e-84 283.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ORY96481.1 - 1.7e-51 175.3 0.0 2.7e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ORY96481.1 - 3.7e-22 78.3 0.0 1.3e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ORY96481.1 - 4e-11 42.8 0.0 1e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 ORY96481.1 - 3.2e-08 33.2 0.2 6.1e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF3603 PF12227.8 ORY96481.1 - 0.022 14.1 0.5 0.043 13.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) ING PF12998.7 ORY96483.1 - 1.4e-16 60.9 1.2 2.3e-16 60.2 1.2 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY96483.1 - 1.9e-05 24.4 9.1 4.5e-05 23.3 9.1 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY96483.1 - 0.00058 19.4 2.5 0.0012 18.4 2.5 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORY96483.1 - 0.019 15.2 1.9 0.051 13.8 1.9 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Cyclin_C_2 PF16899.5 ORY96484.1 - 6.6e-17 61.8 2.6 4.1e-14 52.8 0.2 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 ORY96484.1 - 8.6e-12 44.9 1.1 1.6e-11 44.1 1.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RMI1_N PF08585.12 ORY96484.1 - 0.0013 18.5 0.3 0.0013 18.5 0.3 1.7 2 0 0 2 2 2 1 RecQ mediated genome instability protein TFIIB PF00382.19 ORY96484.1 - 0.0068 16.4 0.0 0.025 14.6 0.0 2.0 2 1 0 2 2 2 1 Transcription factor TFIIB repeat HSF_DNA-bind PF00447.17 ORY96485.1 - 1.2e-32 112.4 1.3 1.2e-32 112.4 1.3 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding Med19 PF10278.9 ORY96485.1 - 0.0066 16.4 1.9 0.012 15.6 1.9 1.3 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 DUF3015 PF11220.8 ORY96485.1 - 0.062 13.2 0.2 0.062 13.2 0.2 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3015) CobT PF06213.12 ORY96485.1 - 0.065 12.6 9.7 0.099 12.0 9.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peroxin-13_N PF04088.13 ORY96485.1 - 0.16 12.2 1.7 0.28 11.5 1.7 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FAM76 PF16046.5 ORY96485.1 - 0.19 11.1 8.6 0.91 8.8 3.7 2.1 2 0 0 2 2 2 0 FAM76 protein Zip PF02535.22 ORY96485.1 - 0.9 8.7 4.7 1.6 7.8 4.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4175 PF13779.6 ORY96485.1 - 0.93 7.3 26.2 1.2 6.9 26.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LMBR1 PF04791.16 ORY96485.1 - 1.1 8.1 2.5 1.4 7.7 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hydin_ADK PF17213.3 ORY96485.1 - 1.2 9.4 5.1 2.4 8.4 5.1 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 ORY96485.1 - 3.2 6.4 7.8 4.6 5.9 7.8 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 ORY96485.1 - 3.9 5.6 23.2 6.4 4.9 23.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NPR1_interact PF15699.5 ORY96485.1 - 5 7.8 8.7 9.5 6.9 8.7 1.4 1 0 0 1 1 1 0 NPR1 interacting SelP_N PF04592.14 ORY96485.1 - 5.7 6.3 20.9 13 5.0 20.9 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.16 ORY96485.1 - 5.8 6.9 8.5 11 5.9 8.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region bZIP_2 PF07716.15 ORY96487.1 - 1.7e-08 34.4 6.9 1.7e-08 34.4 6.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY96487.1 - 5.4e-07 29.6 10.8 1.4e-06 28.3 8.7 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 ORY96487.1 - 0.00091 19.7 3.7 0.00091 19.7 3.7 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor HAUS-augmin3 PF14932.6 ORY96487.1 - 0.071 12.7 11.3 0.092 12.3 11.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TFIIA PF03153.13 ORY96487.1 - 0.89 9.5 8.1 0.89 9.5 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Striatin PF08232.12 ORY96487.1 - 2.9 8.5 11.5 0.23 12.1 1.0 2.2 1 1 1 2 2 2 0 Striatin family SIR2 PF02146.17 ORY96488.1 - 1.5e-57 194.4 0.0 4.8e-57 192.7 0.0 1.8 2 0 0 2 2 2 1 Sir2 family Cytochrom_c3_2 PF14537.6 ORY96488.1 - 1.6 9.3 10.7 5 7.7 0.4 2.5 2 0 0 2 2 2 0 Cytochrome c3 Paired_CXXCH_1 PF09699.10 ORY96488.1 - 2.6 7.9 6.2 0.73 9.6 1.2 2.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF1744 PF08490.12 ORY96489.1 - 4.1e-122 407.6 0.9 6.5e-122 407.0 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 ORY96489.1 - 2.4e-80 270.2 1.5 4.5e-80 269.3 1.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY96489.1 - 5.1e-13 48.5 2.1 8.2e-11 41.3 0.1 4.2 4 1 0 4 4 4 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 ORY96489.1 - 2.8e-09 37.0 0.2 8.2e-09 35.4 0.2 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 ORY96489.1 - 2.5e-05 24.3 0.1 0.00024 21.1 0.0 2.8 2 0 0 2 2 2 1 RNase_H superfamily Cytochrom_c3_2 PF14537.6 ORY96489.1 - 0.13 12.7 4.8 0.39 11.2 4.8 1.8 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 ORY96489.1 - 0.95 9.5 4.0 2.5 8.1 4.0 1.7 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c IMS PF00817.20 ORY96491.1 - 2.3e-46 157.5 0.1 4.4e-46 156.6 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 ORY96491.1 - 2.3e-13 49.5 1.5 4.9e-13 48.4 1.5 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 ORY96491.1 - 2.5e-10 41.0 0.1 8.1e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ORY96491.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Ima1_N PF09779.9 ORY96491.1 - 1.3 9.8 6.2 1.3 9.9 0.5 3.2 3 0 0 3 3 3 0 Ima1 N-terminal domain zf-C2H2_aberr PF17017.5 ORY96492.1 - 9.7e-06 25.8 6.0 0.027 14.6 0.9 2.4 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY96492.1 - 0.0003 21.1 16.8 0.0075 16.7 0.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY96492.1 - 0.011 16.5 16.0 0.045 14.6 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf_Hakai PF18408.1 ORY96492.1 - 0.18 11.5 1.7 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain Smac_DIABLO PF09057.10 ORY96492.1 - 0.23 10.8 1.3 0.36 10.2 0.4 1.8 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases zf_C2H2_ZHX PF18387.1 ORY96492.1 - 9.9 5.9 11.6 8.5 6.1 0.3 3.2 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Gemin7 PF11095.8 ORY96494.1 - 4.6e-16 58.5 0.0 5.4e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) CPSase_L_D2 PF02786.17 ORY96495.1 - 3e-114 379.8 0.1 3.2e-83 278.4 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 ORY96495.1 - 2.5e-47 159.9 0.0 5e-47 158.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORY96495.1 - 1e-46 159.2 0.0 1.6e-45 155.2 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 ORY96495.1 - 1.4e-43 148.1 0.6 8.2e-43 145.6 0.6 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 ORY96495.1 - 8.3e-21 74.0 0.0 3.8e-19 68.7 0.0 3.6 4 0 0 4 4 4 1 MGS-like domain Dala_Dala_lig_C PF07478.13 ORY96495.1 - 3.7e-18 65.8 1.1 6.1e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY96495.1 - 1.9e-14 53.6 0.2 1.1e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORY96495.1 - 2.1e-10 40.4 0.1 4.5e-05 23.2 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 ORY96495.1 - 8.4e-07 29.2 0.5 0.02 14.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 ORY96495.1 - 2.5e-06 27.4 0.0 0.21 11.4 0.0 4.7 4 0 0 4 4 4 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 ORY96495.1 - 6.6e-06 26.0 0.1 0.0053 16.5 0.0 2.5 1 1 1 2 2 2 2 Peptidase C26 Biotin_carb_N PF00289.22 ORY96495.1 - 0.05 14.2 0.2 0.7 10.5 0.0 2.8 2 0 0 2 2 2 0 Biotin carboxylase, N-terminal domain GARS_A PF01071.19 ORY96495.1 - 0.068 12.9 0.4 1.3 8.8 0.0 3.0 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Vps5 PF09325.10 ORY96495.1 - 0.14 11.6 0.2 0.35 10.4 0.2 1.6 1 0 0 1 1 1 0 Vps5 C terminal like PAPS_reduct PF01507.19 ORY96496.1 - 8.7e-30 104.0 0.0 2.3e-19 70.1 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family zf-RING_6 PF14835.6 ORY96497.1 - 7.6e-08 32.1 5.2 1.9e-07 30.8 5.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein BRCT_2 PF16589.5 ORY96497.1 - 4.9e-05 23.7 0.0 0.0033 17.8 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain zf-RING_5 PF14634.6 ORY96497.1 - 9.1e-05 22.3 11.6 9.1e-05 22.3 11.6 2.7 2 1 0 2 2 2 1 zinc-RING finger domain BRCT PF00533.26 ORY96497.1 - 0.00022 21.5 0.0 0.0069 16.7 0.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.6 ORY96497.1 - 0.00027 20.7 11.5 0.00027 20.7 11.5 2.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY96497.1 - 0.00029 20.7 9.2 0.00029 20.7 9.2 2.4 2 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY96497.1 - 0.0023 17.8 9.6 0.0023 17.8 9.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY96497.1 - 0.0043 17.4 12.0 0.0043 17.4 12.0 3.3 3 0 0 3 3 3 1 Ring finger domain TED PF08341.11 ORY96497.1 - 0.065 13.6 1.3 0.14 12.5 1.3 1.5 1 0 0 1 1 1 0 Thioester domain RTT107_BRCT_5 PF16770.5 ORY96497.1 - 0.094 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_UBOX PF13445.6 ORY96497.1 - 0.17 11.9 7.5 0.71 10.0 7.5 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-4CXXC_R1 PF10497.9 ORY96497.1 - 3.5 7.9 12.7 1.8 8.9 1.1 2.8 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_10 PF16685.5 ORY96497.1 - 4.7 7.4 20.2 0.26 11.5 9.2 3.2 3 0 0 3 3 3 0 zinc RING finger of MSL2 DZR PF12773.7 ORY96497.1 - 6.8 6.8 18.4 1.3 9.2 3.5 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 ORY96497.1 - 7.1 6.9 13.4 18 5.6 9.2 2.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Symplekin_C PF12295.8 ORY96498.1 - 8.2e-39 133.6 2.6 1e-38 133.3 0.5 2.3 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 ORY96498.1 - 2.1e-27 96.3 0.2 4.7e-27 95.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HypD PF01924.16 ORY96498.1 - 0.011 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF913 PF06025.12 ORY96498.1 - 0.28 10.1 5.7 4.5 6.1 0.3 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) SPO22 PF08631.10 ORY96498.1 - 0.64 9.5 6.4 0.93 8.9 0.5 3.1 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like Ras PF00071.22 ORY96499.1 - 3.2e-54 182.9 0.0 3.6e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY96499.1 - 5.5e-23 81.5 0.0 9.8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY96499.1 - 1.2e-07 31.4 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY96499.1 - 1.6e-06 28.1 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 ORY96499.1 - 0.034 13.8 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1397 PF07165.11 ORY96499.1 - 0.065 12.6 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) PduV-EutP PF10662.9 ORY96499.1 - 0.11 12.3 0.1 1.7 8.4 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 ORY96499.1 - 0.11 12.8 0.1 0.19 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 ORY96499.1 - 0.14 11.5 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region adh_short PF00106.25 ORY96500.1 - 3.8e-42 144.0 2.1 5e-42 143.6 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY96500.1 - 8.6e-38 130.2 1.6 1.2e-37 129.8 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY96500.1 - 3.5e-06 27.0 0.6 6.8e-06 26.1 0.6 1.4 1 0 0 1 1 1 1 KR domain RRS1 PF04939.12 ORY96500.1 - 0.0033 17.3 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) GH97_C PF14509.6 ORY96500.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation PriCT_2 PF08707.11 ORY96501.1 - 0.044 14.2 0.0 0.84 10.1 0.0 2.3 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Mannosyl_trans3 PF11051.8 ORY96502.1 - 5.8e-39 134.1 0.0 1.3e-26 93.5 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative AAA_2 PF07724.14 ORY96503.1 - 4.9e-56 189.5 0.2 5.5e-52 176.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORY96503.1 - 1.1e-34 118.5 1.8 1.1e-34 118.5 1.8 2.7 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 ORY96503.1 - 9.4e-28 97.3 1.6 2.2e-14 54.0 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY96503.1 - 7.7e-25 86.8 2.0 2.6e-24 85.1 0.0 3.0 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY96503.1 - 2.7e-18 66.3 6.3 3.6e-11 43.2 0.0 4.7 4 2 1 5 5 4 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 ORY96503.1 - 6.1e-16 58.3 0.1 2.3e-08 34.0 0.0 3.8 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 ORY96503.1 - 1.3e-13 51.7 0.3 1.6e-07 31.9 0.0 3.9 2 2 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 ORY96503.1 - 3.7e-10 39.8 0.0 2e-06 27.6 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ORY96503.1 - 1.2e-08 35.3 0.1 0.012 15.8 0.0 4.2 3 2 0 3 3 3 2 AAA domain TniB PF05621.11 ORY96503.1 - 1.7e-08 34.1 0.2 0.00011 21.7 0.0 3.9 3 1 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 ORY96503.1 - 8.5e-08 31.9 0.0 0.001 18.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 ORY96503.1 - 1.7e-07 31.3 0.4 0.076 13.0 0.0 3.9 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 ORY96503.1 - 2.9e-07 30.4 0.0 0.038 13.7 0.0 2.9 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY96503.1 - 6.1e-07 29.0 0.4 0.031 13.7 0.1 3.6 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ORY96503.1 - 4.5e-06 26.0 2.0 0.0091 15.2 0.7 3.3 2 2 0 2 2 2 2 Protein of unknown function (DUF815) Roc PF08477.13 ORY96503.1 - 1.1e-05 25.6 0.0 0.094 12.9 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 ORY96503.1 - 6.1e-05 23.6 1.3 0.63 10.6 0.0 3.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY96503.1 - 8.8e-05 22.5 0.1 0.026 14.4 0.0 2.8 2 1 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 ORY96503.1 - 0.00025 20.8 3.8 1.1 9.0 0.0 4.5 3 1 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ORY96503.1 - 0.00027 21.3 0.0 1.2 9.6 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_24 PF13479.6 ORY96503.1 - 0.00046 20.0 0.1 0.51 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 ORY96503.1 - 0.0011 19.0 0.0 1 9.4 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ORY96503.1 - 0.0014 18.9 0.2 6.4 7.0 0.0 4.0 3 0 0 3 3 3 0 AAA domain Torsin PF06309.11 ORY96503.1 - 0.0018 18.4 0.0 0.0054 16.8 0.0 1.8 1 0 0 1 1 1 1 Torsin AAA_25 PF13481.6 ORY96503.1 - 0.0022 17.6 1.9 0.86 9.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 ORY96503.1 - 0.0023 17.8 0.0 1.4 8.8 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ORY96503.1 - 0.0026 17.7 1.8 2.3 8.1 0.0 4.3 4 0 0 4 4 4 1 NTPase RsgA_GTPase PF03193.16 ORY96503.1 - 0.0028 17.6 0.3 3.8 7.4 0.0 3.1 3 1 0 3 3 2 1 RsgA GTPase ABC_tran PF00005.27 ORY96503.1 - 0.0029 18.1 1.0 0.72 10.4 0.0 3.6 3 2 0 3 3 3 1 ABC transporter ATPase_2 PF01637.18 ORY96503.1 - 0.0044 17.0 9.5 1.4 8.8 0.1 5.1 3 2 2 6 6 5 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 ORY96503.1 - 0.005 16.6 0.2 2.1 8.0 0.0 3.7 4 1 0 4 4 3 1 AAA domain ResIII PF04851.15 ORY96503.1 - 0.0087 16.1 0.0 0.57 10.2 0.0 3.3 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY96503.1 - 0.0094 16.3 0.2 0.25 11.7 0.0 3.1 3 1 0 3 3 2 1 AAA domain DNA_pol3_delta2 PF13177.6 ORY96503.1 - 0.0099 15.7 0.0 4.3 7.1 0.0 3.0 3 0 0 3 3 2 0 DNA polymerase III, delta subunit AAA_33 PF13671.6 ORY96503.1 - 0.018 15.2 0.0 15 5.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 ORY96503.1 - 0.03 14.0 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 ORY96503.1 - 0.099 12.7 0.0 9.7 6.3 0.0 3.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase PseudoU_synth_2 PF00849.22 ORY96503.1 - 0.1 12.7 0.7 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA pseudouridylate synthase AAA_29 PF13555.6 ORY96503.1 - 0.18 11.6 0.0 21 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY96503.1 - 0.24 11.9 16.2 6.2 7.3 0.0 4.1 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 ORY96503.1 - 0.51 10.4 3.0 29 4.6 0.0 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain BLOC1_2 PF10046.9 ORY96503.1 - 0.78 10.1 6.7 0.63 10.4 3.5 2.6 2 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP_bind_1 PF03029.17 ORY96503.1 - 1.7 8.4 6.8 1.7 8.3 0.0 3.5 5 0 0 5 5 2 0 Conserved hypothetical ATP binding protein YchF-GTPase_C PF06071.13 ORY96504.1 - 8.1e-40 134.9 0.1 1.7e-39 133.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY96504.1 - 3.3e-23 81.9 0.0 7.2e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY96504.1 - 6.4e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 ORY96504.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CBM39 PF15886.5 ORY96504.1 - 0.025 14.5 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Dynamin_N PF00350.23 ORY96504.1 - 0.027 14.6 0.0 1.5 8.9 0.1 2.5 1 1 1 2 2 2 0 Dynamin family Myb_DNA-bind_3 PF12776.7 ORY96504.1 - 0.066 14.2 0.1 0.14 13.2 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TGS PF02824.21 ORY96504.1 - 0.083 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 TGS domain FHA PF00498.26 ORY96504.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 FHA domain AAA PF00004.29 ORY96506.1 - 4e-12 46.7 0.1 2e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY96506.1 - 1.4e-06 28.4 0.1 0.00043 20.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 ORY96506.1 - 7.1e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY96506.1 - 1.3e-05 25.4 0.1 7.4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY96506.1 - 2.1e-05 24.6 0.0 0.0001 22.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 ORY96506.1 - 4.5e-05 23.2 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORY96506.1 - 9.1e-05 23.0 0.0 0.0029 18.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 ORY96506.1 - 0.00016 22.1 0.1 0.0023 18.4 0.0 2.6 2 1 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY96506.1 - 0.0009 19.2 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 ORY96506.1 - 0.0014 18.8 0.0 0.028 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY96506.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ORY96506.1 - 0.0055 16.5 0.4 0.84 9.4 0.0 2.9 2 1 1 3 3 3 1 DEAD/DEAH box helicase ABC_tran PF00005.27 ORY96506.1 - 0.0058 17.1 0.7 0.037 14.5 0.0 2.5 2 1 1 3 3 2 1 ABC transporter AAA_2 PF07724.14 ORY96506.1 - 0.0099 16.0 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORY96506.1 - 0.01 15.5 0.6 0.021 14.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_assoc_2 PF16193.5 ORY96506.1 - 0.021 15.1 0.0 0.089 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA C-terminal domain Zeta_toxin PF06414.12 ORY96506.1 - 0.022 14.0 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 ORY96506.1 - 0.028 13.6 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 ORY96506.1 - 0.033 14.0 0.7 0.68 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 ORY96506.1 - 0.046 13.6 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 ORY96506.1 - 0.047 13.9 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 ORY96506.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 ORY96506.1 - 0.067 13.6 1.1 0.18 12.2 0.0 2.3 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 ORY96506.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 ORY96506.1 - 0.088 12.2 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY96506.1 - 0.1 12.5 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 ORY96506.1 - 0.11 12.9 0.2 0.51 10.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY96506.1 - 0.15 11.8 0.2 1.5 8.5 0.2 2.4 1 1 0 1 1 1 0 IstB-like ATP binding protein R3H-assoc PF13902.6 ORY96506.1 - 0.65 10.4 0.0 0.65 10.4 0.0 3.2 3 1 1 4 4 3 0 R3H-associated N-terminal domain Coatomer_WDAD PF04053.14 ORY96507.1 - 5.2e-170 566.3 0.0 5.9e-169 562.8 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 ORY96507.1 - 2.6e-43 145.1 4.3 9.5e-09 35.8 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96507.1 - 3.2e-10 40.2 0.2 0.046 14.0 0.0 6.7 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORY96507.1 - 9e-05 22.5 0.0 4.9 7.3 0.0 4.2 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 ORY96507.1 - 0.024 14.0 0.0 70 2.6 0.0 3.9 2 1 2 4 4 4 0 WD40-like domain Ribosomal_60s PF00428.19 ORY96507.1 - 1.4 9.5 13.8 2.1 9.0 12.2 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNA_Me_trans PF04252.13 ORY96508.1 - 5.9e-60 202.3 0.1 6.9e-60 202.1 0.1 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Sel1 PF08238.12 ORY96509.1 - 1.3e-26 92.4 27.2 1e-06 29.2 0.7 8.5 8 1 0 8 8 8 7 Sel1 repeat TPR_7 PF13176.6 ORY96509.1 - 1.8e-05 24.4 0.7 0.0064 16.4 0.2 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY96509.1 - 2.7e-05 23.8 8.8 0.011 15.6 0.7 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96509.1 - 0.00011 22.0 10.1 0.071 13.2 0.7 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96509.1 - 0.00016 22.2 1.2 0.093 13.6 0.0 5.3 5 3 2 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.9 ORY96509.1 - 0.073 12.8 0.9 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 ORY96509.1 - 0.11 13.0 0.2 7.2 7.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY96509.1 - 0.21 11.9 10.2 0.18 12.0 1.0 4.0 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORY96509.1 - 0.47 10.8 9.0 0.17 12.2 0.9 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY96509.1 - 0.83 10.0 3.8 2.9 8.2 0.3 3.8 3 2 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY96509.1 - 0.95 10.2 14.7 0.95 10.2 0.3 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat NSF PF02071.20 ORY96509.1 - 8 7.7 8.4 51 5.3 0.6 5.3 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat FYVE PF01363.21 ORY96510.1 - 2.3e-19 69.3 7.3 4e-19 68.5 7.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 ORY96510.1 - 0.0085 16.3 8.4 0.031 14.5 8.5 1.8 1 1 0 1 1 1 1 FYVE-type zinc finger Ribosomal_L40e PF01020.17 ORY96510.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.0 2 1 0 2 2 2 0 Ribosomal L40e family C1_1 PF00130.22 ORY96510.1 - 3.4 7.6 9.2 0.81 9.6 5.4 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Yippee-Mis18 PF03226.14 ORY96511.1 - 2.9e-11 43.5 0.1 3.3e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 ORY96511.1 - 0.016 15.3 0.3 0.06 13.4 0.3 1.8 1 1 0 1 1 1 0 SelR domain Tankyrase_bdg_C PF15327.6 ORY96511.1 - 0.079 13.4 0.0 0.092 13.2 0.0 1.1 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain MRP_L53 PF10780.9 ORY96512.1 - 5e-12 45.8 0.2 1e-11 44.8 0.2 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Ras PF00071.22 ORY96513.1 - 6.8e-54 181.8 0.0 7.9e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY96513.1 - 3.1e-21 75.8 0.0 4.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY96513.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY96513.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 ORY96513.1 - 0.023 13.9 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 ORY96513.1 - 0.059 13.3 0.1 0.31 10.9 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase MFS_1 PF07690.16 ORY96514.1 - 1.3e-54 185.5 60.3 5.2e-45 153.9 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY96514.1 - 2.8e-13 49.2 25.4 5.5e-07 28.5 10.8 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORY96514.1 - 1.5e-12 47.1 17.1 1.7e-09 37.1 1.6 3.1 1 1 2 3 3 3 3 MFS_1 like family OATP PF03137.20 ORY96514.1 - 5.2e-12 44.8 4.7 5.2e-12 44.8 4.7 3.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 ORY96514.1 - 7.8e-06 24.6 32.1 2.8e-05 22.8 5.9 3.1 2 1 0 3 3 3 3 Transmembrane secretion effector MFS_4 PF06779.14 ORY96514.1 - 3.6e-05 23.2 6.2 3.6e-05 23.2 6.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Nucleopor_Nup85 PF07575.13 ORY96515.1 - 2e-36 125.8 0.1 1.4e-24 86.6 0.0 2.2 2 0 0 2 2 2 2 Nup85 Nucleoporin IL6 PF00489.17 ORY96515.1 - 0.037 13.6 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family LTV PF04180.14 ORY96516.1 - 7.4e-73 246.5 50.0 1.1e-71 242.6 43.0 3.1 1 1 1 2 2 2 1 Low temperature viability protein MID_MedPIWI PF18296.1 ORY96516.1 - 3.5 7.3 8.5 7.8 6.2 8.5 1.6 1 1 0 1 1 1 0 MID domain of medPIWI Presenilin PF01080.17 ORY96516.1 - 6 5.5 15.1 10 4.8 15.1 1.4 1 0 0 1 1 1 0 Presenilin TPR_1 PF00515.28 ORY96517.1 - 7.7e-06 25.5 0.4 0.039 13.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96517.1 - 1.6e-05 24.6 1.7 0.4 10.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY96517.1 - 2.3e-05 24.6 2.7 0.0029 17.9 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY96517.1 - 7.5e-05 23.3 1.3 0.0072 17.0 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY96517.1 - 0.0021 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.6 ORY96517.1 - 0.0034 17.6 2.5 0.11 12.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY96517.1 - 0.0062 16.7 1.1 4.6 7.5 0.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96517.1 - 0.0078 17.0 0.6 0.13 13.1 0.0 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY96517.1 - 0.013 16.1 1.2 1 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY96517.1 - 0.024 15.1 1.0 0.024 15.1 1.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 ORY96517.1 - 0.036 13.0 0.0 0.17 10.7 0.0 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 ORY96517.1 - 0.057 13.3 5.6 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY96517.1 - 0.11 12.8 1.1 25 5.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SH3_9 PF14604.6 ORY96518.1 - 3.6e-43 145.2 2.6 2.6e-15 56.0 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 ORY96518.1 - 9.9e-42 140.3 2.4 2.2e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 ORY96518.1 - 6.8e-34 115.3 0.0 6.9e-11 41.7 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_10 PF17902.1 ORY96518.1 - 6.9e-05 22.8 0.1 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 SH3 domain Tup_N PF08581.10 ORY96518.1 - 0.023 15.0 1.0 0.044 14.1 1.0 1.4 1 0 0 1 1 1 0 Tup N-terminal Nup54_57_C PF18570.1 ORY96518.1 - 0.042 13.4 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain SH3_3 PF08239.11 ORY96518.1 - 0.52 10.6 5.0 6.1 7.2 0.0 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain WD40 PF00400.32 ORY96519.1 - 1.1e-47 159.0 13.7 1.3e-06 29.0 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96519.1 - 5.8e-13 49.0 1.8 0.0032 17.7 0.0 6.2 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY96519.1 - 8.9e-07 29.0 0.3 0.00064 19.7 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY96519.1 - 0.00013 20.8 1.3 1 7.9 0.0 4.2 1 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY96519.1 - 0.00046 19.6 0.4 0.44 9.8 0.1 3.2 2 1 0 3 3 3 2 WD40-like domain PQQ PF01011.21 ORY96519.1 - 0.00092 19.0 0.4 0.62 10.1 0.1 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat Ge1_WD40 PF16529.5 ORY96519.1 - 0.0029 16.6 0.2 5.3 5.9 0.0 4.0 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 ORY96519.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain Methyltr_RsmB-F PF01189.17 ORY96519.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F AMP-binding PF00501.28 ORY96520.1 - 2.4e-66 224.1 0.0 3.1e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY96520.1 - 3.3e-16 60.0 0.1 1.1e-15 58.4 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 ORY96521.1 - 2e-32 112.7 31.2 1.6e-22 80.0 15.8 3.7 1 1 3 4 4 4 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY96521.1 - 7.5e-30 104.0 36.0 1.2e-29 103.3 36.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 ORY96521.1 - 0.00013 20.8 17.2 0.011 14.4 11.0 3.0 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like CoatB PF10389.9 ORY96521.1 - 0.018 14.9 0.3 0.075 12.9 0.3 2.1 1 0 0 1 1 1 0 Bacteriophage coat protein B Spin-Ssty PF02513.17 ORY96521.1 - 0.18 11.6 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 Spin/Ssty Family Flavokinase PF01687.17 ORY96524.1 - 9.2e-37 125.7 0.0 1.1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase SHNi-TPR PF10516.9 ORY96525.1 - 7.2e-05 22.2 0.3 0.00034 20.0 0.1 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 ORY96525.1 - 7.8e-05 22.9 4.4 0.00052 20.3 2.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96525.1 - 0.00058 19.8 6.7 0.03 14.4 0.2 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY96525.1 - 0.019 14.7 2.7 7.1 6.4 0.0 4.1 5 1 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 ORY96525.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY96525.1 - 0.13 12.2 2.7 0.59 10.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY96525.1 - 0.17 12.5 4.5 8.8 7.1 1.3 3.9 2 2 1 3 3 3 0 Tetratricopeptide repeat DUF3138 PF11336.8 ORY96525.1 - 2.3 6.7 4.2 1.1 7.7 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) NOA36 PF06524.12 ORY96525.1 - 5 6.3 14.8 0.14 11.5 8.4 1.6 2 0 0 2 2 2 0 NOA36 protein Peptidase_M24 PF00557.24 ORY96526.1 - 1.2e-52 178.7 0.0 1.9e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY96526.1 - 1.4e-41 141.1 0.0 2.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dus PF01207.17 ORY96527.1 - 3.2e-60 203.8 0.0 4.9e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 ORY96527.1 - 0.00042 20.0 1.6 0.00042 20.0 1.6 3.0 4 0 0 4 4 4 2 CCCH-type zinc finger DUF4015 PF13200.6 ORY96527.1 - 0.02 13.9 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Lustrin_cystein PF14625.6 ORY96527.1 - 0.19 12.1 1.6 1.5 9.2 0.0 2.9 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain zf_CCCH_4 PF18345.1 ORY96527.1 - 0.37 10.9 13.7 0.31 11.2 1.6 2.8 2 1 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 ORY96527.1 - 2.7 8.0 18.1 0.88 9.6 0.8 3.3 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY96527.1 - 5.6 7.7 12.1 0.35 11.6 2.4 2.9 2 1 1 3 3 3 0 Torus domain EHN PF06441.12 ORY96528.1 - 2.8e-27 95.2 1.9 4.9e-27 94.4 1.9 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY96528.1 - 2.5e-16 60.1 0.1 4.8e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY96528.1 - 0.0013 19.4 0.1 0.0013 19.4 0.1 1.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family SAGA-Tad1 PF12767.7 ORY96529.1 - 5.2e-46 157.3 0.0 5.2e-46 157.3 0.0 2.6 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Robl_LC7 PF03259.17 ORY96530.1 - 2.2e-23 81.8 0.1 2.5e-23 81.7 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 ORY96530.1 - 0.00096 19.0 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF5344 PF17279.2 ORY96530.1 - 0.043 14.4 1.4 0.099 13.2 0.1 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5344) zf-C2H2 PF00096.26 ORY96531.1 - 1.1e-30 104.3 60.8 6.7e-05 23.1 1.6 9.5 9 1 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY96531.1 - 8.7e-25 85.3 51.7 0.00074 20.1 1.0 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY96531.1 - 9.2e-20 70.1 59.4 6.8e-07 29.4 0.7 9.3 10 1 1 11 11 9 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY96531.1 - 2.8e-13 49.8 34.4 0.018 15.4 0.4 8.9 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY96531.1 - 3.5e-08 33.6 26.7 2e-05 24.8 2.2 4.4 1 1 3 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY96531.1 - 9.9e-07 28.6 45.6 0.0003 20.7 0.3 8.3 7 1 1 8 8 8 3 C2H2-type zinc finger zf-met PF12874.7 ORY96531.1 - 6.7e-05 23.1 30.2 0.0063 16.9 0.1 8.1 9 0 0 9 9 8 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 ORY96531.1 - 0.0021 17.6 22.5 1.4 8.6 0.0 6.6 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 ORY96531.1 - 0.0027 17.3 3.6 0.0027 17.3 3.6 5.2 2 1 4 6 6 6 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 ORY96531.1 - 0.0063 17.2 3.5 0.0063 17.2 3.5 4.8 2 2 2 4 4 4 1 Zinc finger C2H2-type, 3 repeats SUIM_assoc PF16619.5 ORY96531.1 - 0.024 14.7 1.8 0.024 14.7 1.8 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ADK_lid PF05191.14 ORY96531.1 - 0.026 14.5 7.7 0.52 10.3 0.2 4.6 3 1 1 4 4 4 0 Adenylate kinase, active site lid Ig_4 PF16680.5 ORY96531.1 - 0.065 13.5 1.4 1.6 9.0 0.1 3.5 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain zf-Di19 PF05605.12 ORY96531.1 - 0.16 12.3 44.5 0.3 11.4 0.4 6.0 5 2 1 6 6 5 0 Drought induced 19 protein (Di19), zinc-binding A2L_zn_ribbon PF08792.10 ORY96531.1 - 0.18 11.5 0.1 0.18 11.5 0.1 5.1 7 0 0 7 7 6 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 ORY96531.1 - 0.23 11.6 27.1 1.2 9.3 2.3 5.4 3 2 2 5 5 5 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 ORY96531.1 - 0.3 10.9 0.2 0.3 10.9 0.2 4.8 6 0 0 6 6 5 0 zinc-finger C2H2-type ANAPC_CDC26 PF10471.9 ORY96531.1 - 0.69 10.8 10.2 0.072 13.9 4.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Rep_fac-A_C PF08646.10 ORY96531.1 - 1.1 8.9 12.7 4.8 6.9 0.4 4.3 1 1 3 4 4 4 0 Replication factor-A C terminal domain zf-C2H2_2 PF12756.7 ORY96531.1 - 3.7 8.0 33.6 0.81 10.1 8.7 6.4 1 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 ORY96531.1 - 5.4 7.4 22.3 53 4.2 0.0 7.2 8 0 0 8 8 7 0 zinc-ribbon DUF4428 PF14471.6 ORY96531.1 - 8.2 6.4 9.6 21 5.1 0.0 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4428) LIM PF00412.22 ORY96531.1 - 8.8 6.6 25.2 1.3 9.3 1.5 4.9 2 1 3 5 5 5 0 LIM domain zf-C2HC_2 PF13913.6 ORY96532.1 - 0.0077 16.1 0.5 0.013 15.4 0.5 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF1922 PF09082.10 ORY96532.1 - 0.14 12.5 0.2 0.21 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) BTB_2 PF02214.22 ORY96533.1 - 3.5e-19 68.9 0.1 1.1e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Pap_E4 PF02711.14 ORY96533.1 - 0.084 13.9 4.8 0.18 12.8 4.8 1.6 1 0 0 1 1 1 0 E4 protein PAPA-1 PF04795.12 ORY96534.1 - 5.3e-20 72.0 5.4 5.3e-20 72.0 5.4 2.9 2 1 1 3 3 3 1 PAPA-1-like conserved region zf-HIT PF04438.16 ORY96534.1 - 0.012 15.4 0.9 0.016 15.0 0.9 1.2 1 0 0 1 1 1 0 HIT zinc finger Polysacc_deac_2 PF04748.13 ORY96534.1 - 0.032 13.4 0.7 0.086 12.0 0.4 1.8 1 1 0 2 2 2 0 Divergent polysaccharide deacetylase SDA1 PF05285.12 ORY96534.1 - 4.5 6.6 46.8 6 6.2 46.8 1.1 1 0 0 1 1 1 0 SDA1 TAN PF11640.8 ORY96535.1 - 0.24 11.5 1.3 3.6 7.7 0.0 2.9 3 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair HECT PF00632.25 ORY96536.1 - 5.5e-93 311.8 0.0 6.6e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 ORY96537.1 - 1.4e-12 47.5 0.0 3.7e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96537.1 - 1.7e-12 47.2 0.0 3.5e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase TFR_dimer PF04253.15 ORY96538.1 - 1.1e-25 90.1 0.1 2.2e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORY96538.1 - 8.1e-15 55.0 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY96538.1 - 1e-10 41.5 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 PA domain Med10 PF09748.9 ORY96538.1 - 0.032 14.2 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex FbpA PF05833.11 ORY96538.1 - 0.13 11.0 1.6 0.19 10.4 1.6 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Nicastrin PF05450.15 ORY96538.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Nicastrin FemAB PF02388.16 ORY96538.1 - 0.3 9.9 2.8 0.48 9.2 2.8 1.2 1 0 0 1 1 1 0 FemAB family ATP-synt_ab PF00006.25 ORY96539.1 - 2.8e-68 229.8 0.0 4.1e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY96539.1 - 3.8e-12 46.5 0.5 7.6e-12 45.6 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 ORY96539.1 - 0.02 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5535) HAS-barrel PF09378.10 ORY96539.1 - 0.059 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 HAS barrel domain DUF3533 PF12051.8 ORY96539.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) LRR_4 PF12799.7 ORY96540.1 - 4.4e-05 23.7 5.7 1.5 9.3 0.1 5.9 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY96540.1 - 0.00051 19.9 2.8 0.22 11.7 0.1 4.3 5 0 0 5 5 5 2 Leucine Rich repeat F-box-like PF12937.7 ORY96540.1 - 0.011 15.7 0.3 0.052 13.5 0.1 2.4 2 0 0 2 2 2 0 F-box-like LRR_1 PF00560.33 ORY96540.1 - 0.19 12.4 14.0 20 6.2 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 ORY96541.1 - 0.0018 18.4 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1296 PF06972.11 ORY96541.1 - 0.023 14.8 0.2 0.094 12.9 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) U-box PF04564.15 ORY96541.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain Metal_resist PF13801.6 ORY96541.1 - 0.11 12.7 1.9 0.24 11.6 1.9 1.6 1 0 0 1 1 1 0 Heavy-metal resistance NOA36 PF06524.12 ORY96541.1 - 3.4 6.9 7.6 6.5 6.0 7.6 1.4 1 0 0 1 1 1 0 NOA36 protein Cupin_8 PF13621.6 ORY96542.1 - 2.1e-72 243.9 0.1 2.5e-72 243.7 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY96542.1 - 0.0056 17.1 0.1 0.55 10.7 0.0 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 ORY96542.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein GPI PF06560.11 ORY96542.1 - 0.18 11.0 0.0 0.62 9.3 0.0 1.8 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Cpn60_TCP1 PF00118.24 ORY96543.1 - 6.4e-159 529.7 5.7 7.3e-159 529.5 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 ORY96543.1 - 0.15 12.5 0.0 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Methyltransf_11 PF08241.12 ORY96544.1 - 1.2e-05 25.9 0.1 3.1e-05 24.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY96544.1 - 0.022 15.5 0.0 0.058 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Rad1 PF02144.16 ORY96545.1 - 8.5e-41 139.8 0.0 1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 ORY96545.1 - 0.003 17.7 0.0 0.011 15.9 0.0 1.8 1 1 1 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain zf-C2H2_4 PF13894.6 ORY96546.1 - 1.6e-08 34.6 54.7 0.045 14.6 1.3 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger Nop14 PF04147.12 ORY96546.1 - 0.00084 17.7 32.2 0.0013 17.1 32.2 1.2 1 0 0 1 1 1 1 Nop14-like family zf-Di19 PF05605.12 ORY96546.1 - 0.0046 17.2 13.2 0.0066 16.7 10.4 5.8 5 2 1 6 6 5 4 Drought induced 19 protein (Di19), zinc-binding CDC45 PF02724.14 ORY96546.1 - 0.017 13.4 26.3 0.024 12.9 26.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 ORY96546.1 - 0.02 13.4 33.6 0.026 13.0 33.6 1.1 1 0 0 1 1 1 0 Mpp10 protein zf-C2H2_6 PF13912.6 ORY96546.1 - 0.021 14.8 30.0 1.8 8.7 1.3 6.2 6 0 0 6 6 6 0 C2H2-type zinc finger ADK_lid PF05191.14 ORY96546.1 - 0.054 13.5 0.9 0.054 13.5 0.9 4.0 3 1 0 3 3 3 0 Adenylate kinase, active site lid PRP21_like_P PF12230.8 ORY96546.1 - 0.073 12.9 0.1 0.073 12.9 0.1 2.9 2 1 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein SDA1 PF05285.12 ORY96546.1 - 0.14 11.6 36.7 0.19 11.1 36.7 1.1 1 0 0 1 1 1 0 SDA1 zf-C2H2 PF00096.26 ORY96546.1 - 0.22 12.0 56.7 0.24 11.9 6.0 7.1 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-RRN7 PF11781.8 ORY96546.1 - 0.56 9.9 0.0 0.56 9.9 0.0 3.2 4 0 0 4 4 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_ribbon_SprT PF17283.2 ORY96546.1 - 2.4 8.1 20.5 16 5.5 0.0 5.4 5 0 0 5 5 5 0 SprT-like zinc ribbon domain Cwf_Cwc_15 PF04889.12 ORY96546.1 - 2.6 7.7 33.0 4.3 7.0 33.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 ORY96546.1 - 2.8 6.6 18.0 4.2 6.0 18.0 1.2 1 0 0 1 1 1 0 Presenilin zf-met PF12874.7 ORY96546.1 - 3 8.4 36.9 1.9 9.0 3.0 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type SLC12 PF03522.15 ORY96546.1 - 3.9 6.4 14.5 6.4 5.7 14.5 1.3 1 0 0 1 1 1 0 Solute carrier family 12 MDM1 PF15501.6 ORY96546.1 - 5.2 6.1 22.4 8.9 5.3 22.4 1.3 1 0 0 1 1 1 0 Nuclear protein MDM1 AAA_11 PF13086.6 ORY96546.1 - 6.6 6.4 10.3 13 5.5 10.3 1.5 1 0 0 1 1 1 0 AAA domain Baculo_IE-1 PF05290.11 ORY96546.1 - 7.5 6.5 12.9 1.3 9.0 0.4 3.9 2 2 2 4 4 4 0 Baculovirus immediate-early protein (IE-0) Nop53 PF07767.11 ORY96546.1 - 8.9 5.6 33.3 10 5.3 31.5 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) NOB1_Zn_bind PF08772.11 ORY96547.1 - 3.4e-32 110.4 2.1 6.5e-32 109.5 2.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 ORY96547.1 - 1.7e-27 95.7 0.3 4.8e-27 94.3 0.1 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease DZR PF12773.7 ORY96547.1 - 0.03 14.3 1.4 0.047 13.7 0.5 1.7 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 ORY96547.1 - 0.061 14.1 1.6 0.19 12.5 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon family SinI PF08671.10 ORY96547.1 - 0.065 13.0 0.1 7.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Anti-repressor SinI HypA PF01155.19 ORY96547.1 - 0.067 13.2 0.7 0.15 12.1 0.7 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WRNPLPNID PF15017.6 ORY96547.1 - 7.2 7.6 16.4 18 6.3 6.4 3.3 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box S-AdoMet_synt_C PF02773.16 ORY96550.1 - 1.6e-70 235.4 0.2 3.8e-70 234.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORY96550.1 - 3.5e-46 156.4 0.0 6.7e-46 155.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORY96550.1 - 2.7e-45 153.1 0.1 5.3e-45 152.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORY96550.1 - 0.046 12.5 0.4 0.13 11.0 0.1 1.7 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) AlaDh_PNT_N PF05222.15 ORY96551.1 - 6.4e-28 97.7 0.0 1.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 ORY96551.1 - 9.1e-07 28.4 0.0 2.1e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 ORY96552.1 - 1.4e-25 89.1 2.0 0.00055 20.7 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 ORY96552.1 - 4e-19 68.6 1.3 1.2e-18 67.2 0.3 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 ORY96552.1 - 0.0014 18.9 0.9 0.7 10.2 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain 7tm_3 PF00003.22 ORY96553.1 - 6.4e-16 58.8 7.3 7.1e-16 58.7 7.3 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR UPF0014 PF03649.13 ORY96553.1 - 0.00052 19.4 1.1 0.00078 18.9 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Ail_Lom PF06316.11 ORY96553.1 - 0.04 13.7 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein FtsX PF02687.21 ORY96553.1 - 1.3 9.6 7.0 4 8.0 5.3 2.2 1 1 1 2 2 2 0 FtsX-like permease family DHHC PF01529.20 ORY96553.1 - 5.6 7.1 8.5 7.6 6.6 0.5 2.3 1 1 0 2 2 2 0 DHHC palmitoyltransferase ANF_receptor PF01094.28 ORY96554.1 - 5.1e-36 124.5 0.5 6.4e-36 124.2 0.5 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY96554.1 - 8.9e-14 51.9 4.5 1.4e-13 51.3 4.5 1.3 1 1 0 1 1 1 1 Periplasmic binding protein DSBA PF01323.20 ORY96555.1 - 8.3e-40 136.6 0.1 1e-39 136.4 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY96555.1 - 2.4e-06 27.8 0.4 9.3e-06 25.9 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 ORY96555.1 - 0.00074 19.5 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain DIL PF01843.19 ORY96556.1 - 2.7e-25 88.6 4.8 9.4e-25 86.9 4.8 2.0 1 0 0 1 1 1 1 DIL domain Ank_5 PF13857.6 ORY96556.1 - 0.14 12.5 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Gamma-thionin PF00304.20 ORY96557.1 - 0.031 14.5 4.5 0.048 13.9 4.5 1.3 1 0 0 1 1 1 0 Gamma-thionin family Toxin_31 PF08119.11 ORY96557.1 - 0.28 10.9 4.3 0.5 10.2 4.3 1.4 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family PTN_MK_N PF05196.13 ORY96557.1 - 0.73 10.1 4.5 0.37 11.1 2.1 1.7 1 1 1 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain Defensin_2 PF01097.18 ORY96557.1 - 2.1 8.4 7.1 3.1 7.8 7.1 1.2 1 0 0 1 1 1 0 Arthropod defensin Ferric_reduct PF01794.19 ORY96558.1 - 1.3e-17 64.1 12.7 1.3e-17 64.1 12.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY96558.1 - 1.3e-10 41.6 0.0 1.5e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Pro-rich PF15240.6 ORY96559.1 - 0.15 12.3 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Proline-rich PTH2 PF01981.16 ORY96560.1 - 3.2e-16 59.7 0.0 3.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DASH_Dad3 PF08656.10 ORY96561.1 - 2e-12 47.0 0.2 2.2e-12 46.9 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 YABBY PF04690.13 ORY96562.1 - 1.2e-11 45.5 0.4 1.4e-11 45.3 0.4 1.0 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 ORY96562.1 - 4.4e-08 33.4 1.0 5.8e-08 33.0 1.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY96562.1 - 2.2e-07 31.4 1.0 2.7e-07 31.1 1.0 1.1 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 ORY96562.1 - 5.1e-07 30.3 2.2 5.3e-07 30.3 2.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 RGS PF00615.19 ORY96563.1 - 4e-12 46.4 0.0 4.3e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Aldo_ket_red PF00248.21 ORY96565.1 - 1.2e-81 274.1 0.1 1.5e-81 273.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tti2 PF10521.9 ORY96565.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Tti2 family zf-TRAF PF02176.18 ORY96566.1 - 3e-13 50.3 28.6 2.3e-07 31.4 8.7 4.2 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 ORY96566.1 - 2.3e-06 27.4 9.1 2.3e-06 27.4 9.1 3.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY96566.1 - 6e-06 26.0 13.5 6e-06 26.0 13.5 3.9 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY96566.1 - 8e-06 26.1 13.2 8e-06 26.1 13.2 3.8 2 1 1 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY96566.1 - 1.4e-05 25.0 16.0 1.4e-05 25.0 16.0 2.5 3 0 0 3 3 1 1 RING-type zinc-finger U-box PF04564.15 ORY96566.1 - 1.7e-05 24.9 0.2 0.0003 20.9 0.0 3.0 3 0 0 3 3 3 1 U-box domain zf-TRAF_2 PF15965.5 ORY96566.1 - 5.5e-05 23.5 28.3 0.00015 22.2 2.5 4.4 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-C3HC4 PF00097.25 ORY96566.1 - 0.00025 20.8 13.4 0.00025 20.8 13.4 3.9 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 ORY96566.1 - 0.00054 20.0 28.7 0.0039 17.1 4.0 4.6 1 1 3 5 5 5 3 Seven in absentia protein family zf-C3HC4_4 PF15227.6 ORY96566.1 - 0.00055 20.0 15.9 0.00055 20.0 15.9 3.7 2 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY96566.1 - 0.0036 17.1 11.2 0.0036 17.1 11.2 3.3 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY96566.1 - 0.0069 16.3 12.4 0.0069 16.3 12.4 3.7 2 2 1 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY96566.1 - 0.03 14.6 7.4 0.03 14.6 7.4 4.0 2 1 0 2 2 1 0 RING-H2 zinc finger domain Vpu PF00558.19 ORY96566.1 - 0.12 12.1 1.2 0.28 11.0 1.2 1.6 1 0 0 1 1 1 0 Vpu protein Csm1_N PF18504.1 ORY96566.1 - 0.14 12.5 9.5 0.14 12.5 4.6 2.7 2 1 0 2 2 2 0 Csm1 N-terminal domain DUF3138 PF11336.8 ORY96566.1 - 1.5 7.3 3.7 2.2 6.8 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PRKG1_interact PF15898.5 ORY96566.1 - 4 8.4 15.9 1.9 9.4 13.4 1.7 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain FapA PF03961.13 ORY96566.1 - 4.3 5.8 5.3 7.5 5.0 5.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 ORY96566.1 - 4.5 6.4 7.5 8.6 5.5 7.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein Cript PF10235.9 ORY96566.1 - 6.9 7.3 17.8 1.4 9.5 7.1 3.1 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Cnn_1N PF07989.11 ORY96566.1 - 8.7 6.6 17.2 14 5.9 8.1 3.3 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 CN_hydrolase PF00795.22 ORY96567.1 - 6.1e-32 111.0 0.0 7.2e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GGACT PF06094.12 ORY96568.1 - 1.6e-20 73.9 0.0 2.2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like APG6_N PF17675.1 ORY96569.1 - 0.0036 17.8 20.1 0.011 16.3 6.0 2.3 2 0 0 2 2 2 2 Apg6 coiled-coil region Spc7 PF08317.11 ORY96569.1 - 0.022 13.6 11.3 0.035 13.0 11.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 ORY96569.1 - 0.045 13.8 19.0 0.22 11.6 5.8 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PI_PP_I PF18363.1 ORY96569.1 - 0.062 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain CENP-F_leu_zip PF10473.9 ORY96569.1 - 0.065 13.3 9.4 0.49 10.4 0.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 ORY96569.1 - 0.1 12.9 1.7 15 6.0 0.2 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MutS_III PF05192.18 ORY96569.1 - 0.12 12.6 3.4 0.25 11.5 2.3 1.9 2 0 0 2 2 2 0 MutS domain III WXG100 PF06013.12 ORY96569.1 - 0.22 11.8 6.9 0.83 9.9 0.3 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG YabA PF06156.13 ORY96569.1 - 0.23 12.1 5.9 3.3 8.4 0.8 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Prefoldin PF02996.17 ORY96569.1 - 0.53 10.2 3.9 1.4 8.8 0.3 2.7 2 0 0 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 ORY96569.1 - 0.73 9.4 5.4 5 6.7 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 ORY96569.1 - 0.84 9.8 5.1 17 5.6 0.4 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 ORY96569.1 - 1.3 9.6 5.1 1.8 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 HisKA_3 PF07730.13 ORY96569.1 - 1.3 9.6 18.8 0.37 11.3 4.4 3.7 3 1 1 4 4 4 0 Histidine kinase TMPIT PF07851.13 ORY96569.1 - 2.7 7.2 7.5 2.1 7.5 0.6 2.2 1 1 2 3 3 3 0 TMPIT-like protein CorA PF01544.18 ORY96569.1 - 3.1 7.0 10.1 0.22 10.8 3.3 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Cluap1 PF10234.9 ORY96569.1 - 4.3 6.7 15.8 29 3.9 16.0 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 TEX13 PF15186.6 ORY96569.1 - 4.9 6.8 18.2 0.41 10.3 5.5 2.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Phage_GPO PF05929.11 ORY96569.1 - 5.2 6.6 9.8 3.1 7.4 1.7 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 ORY96569.1 - 7.4 5.9 17.3 2.9 7.2 4.7 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 ORY96569.1 - 9.8 3.9 11.2 0.38 8.6 1.5 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family MRP-L46 PF11788.8 ORY96570.1 - 2.3e-17 63.8 5.6 3.9e-17 63.1 3.7 2.2 1 1 1 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 ORY96570.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Myb_DNA-bind_6 PF13921.6 ORY96571.1 - 0.00032 20.9 0.9 0.00053 20.2 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY96571.1 - 0.0015 18.6 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_2 PF07719.17 ORY96573.1 - 1.6e-11 43.4 7.2 0.41 10.9 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY96573.1 - 4.3e-11 43.1 6.4 3.3e-05 24.3 0.3 5.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY96573.1 - 4.2e-10 39.3 0.0 0.014 15.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY96573.1 - 1.2e-08 34.4 4.8 0.65 9.9 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96573.1 - 2.3e-08 34.1 7.9 1 10.4 0.1 6.9 3 3 4 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY96573.1 - 3.6e-05 23.9 6.9 0.33 11.2 0.0 4.4 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORY96573.1 - 4.1e-05 24.1 0.9 4.8 7.9 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY96573.1 - 5.8e-05 23.3 5.6 0.11 12.9 0.0 4.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY96573.1 - 0.00011 21.8 0.3 17 5.2 0.0 5.8 6 1 1 7 7 7 0 TPR repeat TPR_9 PF13371.6 ORY96573.1 - 0.00046 20.3 0.3 0.58 10.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3243 PF11588.8 ORY96573.1 - 0.00066 19.9 1.1 0.0037 17.6 0.0 2.5 3 0 0 3 3 2 1 Protein of unknown function (DUF3243) TPR_8 PF13181.6 ORY96573.1 - 0.0014 18.7 11.1 39 4.8 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY96573.1 - 0.0025 17.8 0.3 0.27 11.4 0.0 3.9 3 1 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 ORY96573.1 - 0.0029 17.5 2.3 5.7 7.2 0.1 4.4 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY96573.1 - 0.0044 16.5 6.0 0.021 14.2 2.8 2.9 2 1 1 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 ORY96573.1 - 0.56 11.0 3.9 20 6.1 0.0 4.1 4 1 0 4 4 3 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 ORY96574.1 - 2.1e-20 73.3 0.6 1.8e-09 37.3 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 ORY96574.1 - 0.0033 18.0 0.0 0.27 11.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY96574.1 - 0.0042 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY96574.1 - 0.012 14.9 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY96574.1 - 0.078 12.0 0.0 7 5.6 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Uricase PF01014.18 ORY96575.1 - 2.1e-66 222.1 2.7 1.1e-33 116.3 1.8 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY96575.1 - 0.0001 22.8 1.9 0.00024 21.6 1.4 1.7 2 0 0 2 2 2 1 Dihydroneopterin aldolase PX PF00787.24 ORY96575.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 PX domain GPI-anchored PF10342.9 ORY96576.1 - 1.2e-11 45.2 0.2 1.2e-11 45.2 0.2 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Apc13p PF05839.11 ORY96577.1 - 1e-05 25.6 0.1 1.3e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Apc13p protein PLDc PF00614.22 ORY96578.1 - 6e-14 51.6 0.7 6.4e-07 29.3 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORY96578.1 - 1.9e-11 44.0 0.1 2.3e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 ORY96578.1 - 0.0024 17.9 0.3 0.0024 17.9 0.3 3.3 4 1 0 4 4 4 1 PX domain PH PF00169.29 ORY96578.1 - 0.0042 17.6 0.4 0.011 16.2 0.4 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 ORY96578.1 - 0.12 12.7 0.4 0.41 11.0 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Integrase_H2C2 PF17921.1 ORY96579.1 - 6.9e-09 35.7 0.6 2.2e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 ORY96579.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RskA PF10099.9 ORY96579.1 - 0.44 10.8 6.1 2.2 8.5 0.1 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DUF2464 PF10240.9 ORY96579.1 - 0.69 9.4 4.9 1.3 8.5 4.9 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 AAA PF00004.29 ORY96580.1 - 2.4e-15 57.1 0.0 5.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 ORY96580.1 - 6e-10 39.4 0.1 9.8e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA_5 PF07728.14 ORY96580.1 - 5.7e-05 23.1 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ORY96580.1 - 0.00095 18.7 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 ORY96580.1 - 0.0017 18.1 0.2 0.0042 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY96580.1 - 0.002 18.5 0.0 0.012 16.1 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 ORY96580.1 - 0.0034 17.2 1.9 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY96580.1 - 0.0035 17.1 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 ORY96580.1 - 0.005 15.8 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 ORY96580.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 ORY96580.1 - 0.023 14.3 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORY96580.1 - 0.024 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY96580.1 - 0.028 14.6 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY96580.1 - 0.034 14.7 0.5 0.12 13.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 ORY96580.1 - 0.063 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORY96580.1 - 0.07 13.4 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY96580.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY96580.1 - 0.095 12.9 0.1 0.37 11.0 0.1 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY96580.1 - 0.1 12.5 0.2 0.76 9.7 0.0 2.4 3 0 0 3 3 3 0 NACHT domain IBN_N PF03810.19 ORY96581.1 - 1.1e-15 57.3 3.6 7.8e-15 54.6 0.2 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 ORY96581.1 - 8.6e-12 44.6 0.0 7.5e-11 41.5 0.0 2.2 1 1 0 1 1 1 1 Cse1 Xpo1 PF08389.12 ORY96581.1 - 3e-07 30.6 0.8 3e-07 30.6 0.8 4.3 5 0 0 5 5 5 1 Exportin 1-like protein NUC173 PF08161.12 ORY96581.1 - 0.00049 19.8 0.5 0.019 14.6 0.1 2.6 2 0 0 2 2 2 1 NUC173 domain RIX1 PF08167.12 ORY96581.1 - 0.0058 16.4 0.4 0.37 10.5 0.0 3.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 ORY96581.1 - 0.14 12.4 0.8 1.8 8.7 0.1 3.1 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 ORY96581.1 - 0.16 10.4 3.8 0.44 9.0 0.1 2.6 3 0 0 3 3 3 0 Adaptin N terminal region DUF3439 PF11921.8 ORY96582.1 - 0.99 9.4 14.3 0.088 12.8 8.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) FSA_C PF10479.9 ORY96582.1 - 1.1 7.3 5.5 1.9 6.5 5.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 ORY96582.1 - 3.7 5.6 16.5 5.7 5.0 16.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 VASt PF16016.5 ORY96583.1 - 1.6e-40 139.0 3.4 1.7e-40 138.9 1.9 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ORY96583.1 - 8.3e-26 90.1 0.0 1.4e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Flg_hook PF02120.16 ORY96583.1 - 0.025 14.5 1.7 0.055 13.4 1.7 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Peptidase_S49_N PF08496.10 ORY96583.1 - 0.064 13.3 3.3 0.2 11.7 3.3 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF5645 PF18713.1 ORY96583.1 - 0.69 10.2 3.7 0.65 10.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5645) Ctr PF04145.15 ORY96583.1 - 0.79 10.3 2.4 2.4 8.8 0.1 2.8 2 0 0 2 2 2 0 Ctr copper transporter family CrgA PF06781.12 ORY96583.1 - 2.9 8.0 4.1 1.5 8.9 0.8 2.4 2 1 0 2 2 2 0 Cell division protein CrgA Ank_4 PF13637.6 ORY96584.1 - 7.2e-25 87.0 2.8 3.1e-12 46.7 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY96584.1 - 2.5e-20 72.0 5.1 3.5e-07 30.4 0.2 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 ORY96584.1 - 5.5e-19 68.6 0.7 1.4e-12 48.0 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY96584.1 - 8e-16 56.6 0.0 2.3e-07 30.6 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY96584.1 - 1.1e-15 57.4 1.6 2.1e-07 31.1 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Septin PF00735.18 ORY96585.1 - 8.3e-107 356.6 0.0 1.1e-106 356.3 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY96585.1 - 1.1e-08 35.1 0.0 2.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY96585.1 - 6.5e-07 29.1 2.6 4.7e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY96585.1 - 8.9e-06 25.7 1.7 5.7e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ORY96585.1 - 0.00013 22.3 0.1 0.00045 20.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY96585.1 - 0.00075 18.9 0.4 0.0051 16.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family IIGP PF05049.13 ORY96585.1 - 0.00091 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 ORY96585.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 ORY96585.1 - 0.0024 18.1 0.0 0.006 16.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 ORY96585.1 - 0.003 16.7 0.1 0.0073 15.4 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Pox_A32 PF04665.12 ORY96585.1 - 0.003 17.0 0.1 0.0074 15.8 0.1 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein Ras PF00071.22 ORY96585.1 - 0.004 16.8 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY96585.1 - 0.012 15.0 0.0 0.048 13.0 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY96585.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain Dynamin_N PF00350.23 ORY96585.1 - 0.018 15.1 3.1 1.8 8.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_24 PF13479.6 ORY96585.1 - 0.021 14.6 0.1 0.064 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ORY96585.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 ORY96585.1 - 0.025 15.1 8.3 0.55 10.7 8.3 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY96585.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 ORY96585.1 - 0.043 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ORY96585.1 - 0.044 14.0 0.2 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORY96585.1 - 0.057 13.2 0.1 6.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORY96585.1 - 0.077 13.5 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_19 PF13245.6 ORY96585.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Spt20 PF12090.8 ORY96586.1 - 0.012 15.3 23.8 0.015 14.9 23.8 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 ORY96586.1 - 0.25 11.3 17.5 0.25 11.3 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YlqD PF11068.8 ORY96586.1 - 0.37 11.2 17.9 0.48 10.8 17.9 1.1 1 0 0 1 1 1 0 YlqD protein SprA-related PF12118.8 ORY96586.1 - 0.87 8.7 16.3 0.99 8.5 16.3 1.1 1 0 0 1 1 1 0 SprA-related family Androgen_recep PF02166.16 ORY96586.1 - 1.3 7.8 15.4 1.2 7.9 15.4 1.1 1 0 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.8 ORY96586.1 - 1.5 7.7 25.2 1.7 7.5 25.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DivIC PF04977.15 ORY96586.1 - 4.8 7.0 13.5 7.2 6.5 13.5 1.3 1 0 0 1 1 1 0 Septum formation initiator NEMP PF10225.9 ORY96586.1 - 6 6.5 5.2 6.7 6.3 5.2 1.1 1 0 0 1 1 1 0 NEMP family SurA_N_2 PF13623.6 ORY96586.1 - 6.2 6.7 16.5 9 6.2 16.5 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Rad51 PF08423.11 ORY96587.1 - 3.8e-17 62.4 0.3 4.7e-17 62.1 0.3 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 ORY96587.1 - 0.004 16.5 0.3 0.0061 15.9 0.3 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.21 ORY96587.1 - 0.008 15.7 0.0 0.0082 15.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein NRD1_2 PF01995.16 ORY96587.1 - 0.0098 15.2 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 PAXNEB PF05625.11 ORY96587.1 - 0.067 12.3 0.1 0.082 12.0 0.1 1.2 1 0 0 1 1 1 0 PAXNEB protein HHH_5 PF14520.6 ORY96587.1 - 0.089 13.4 0.9 0.17 12.5 0.9 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain PTPLA PF04387.14 ORY96588.1 - 2.2e-54 183.6 10.7 2.2e-54 183.6 10.7 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA MFS_1 PF07690.16 ORY96589.1 - 1.1e-34 119.9 72.6 1.4e-27 96.6 43.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY96589.1 - 2.5e-08 33.2 29.4 4.4e-07 29.1 6.0 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Gram_pos_anchor PF00746.21 ORY96589.1 - 0.095 12.7 0.0 0.095 12.7 0.0 3.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif NAD_binding_1 PF00175.21 ORY96590.1 - 6.8e-32 110.4 0.0 1.4e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY96590.1 - 7.9e-26 90.3 0.0 1.7e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY96590.1 - 1.8e-08 34.7 0.0 2.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Velvet PF11754.8 ORY96592.1 - 1.1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.2 1 1 0 1 1 1 1 Velvet factor Velvet PF11754.8 ORY96593.1 - 1.5e-16 61.2 0.2 1.5e-16 61.2 0.2 1.9 2 1 0 2 2 2 1 Velvet factor Hist_deacetyl PF00850.19 ORY96594.1 - 4.9e-56 190.5 0.0 7.8e-56 189.8 0.0 1.3 1 1 0 1 1 1 1 Histone deacetylase domain bZIP_1 PF00170.21 ORY96595.1 - 5.5e-12 45.6 11.0 5.5e-12 45.6 11.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY96595.1 - 2.3e-06 27.6 11.4 4e-06 26.8 11.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Nnf1 PF03980.14 ORY96595.1 - 0.018 15.4 5.3 0.029 14.8 5.3 1.3 1 0 0 1 1 1 0 Nnf1 bZIP_Maf PF03131.17 ORY96595.1 - 0.028 14.9 10.0 0.051 14.1 9.8 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 ORY96595.1 - 0.084 12.2 1.9 0.11 11.8 1.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF334 PF03904.13 ORY96595.1 - 0.14 11.7 1.4 0.18 11.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DivIC PF04977.15 ORY96595.1 - 0.17 11.7 3.7 0.3 10.9 3.7 1.4 1 0 0 1 1 1 0 Septum formation initiator G-gamma PF00631.22 ORY96595.1 - 3.7 7.6 5.4 2.1 8.4 0.4 2.3 1 1 1 2 2 2 0 GGL domain Forkhead PF00250.18 ORY96596.1 - 1.7e-31 108.3 0.1 3.7e-31 107.2 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain DUF2838 PF10998.8 ORY96597.1 - 2.5e-43 146.8 7.6 2.5e-43 146.8 7.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.18 ORY96597.1 - 0.057 13.3 5.4 0.087 12.7 5.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fungal_trans PF04082.18 ORY96598.1 - 1.8e-11 43.6 0.1 3.9e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DASH_Dad2 PF08654.10 ORY96598.1 - 0.23 11.9 0.7 0.65 10.4 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 ORY96598.1 - 0.3 10.9 1.2 0.49 10.2 0.2 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 Mito_fiss_reg PF05308.11 ORY96598.1 - 6.4 6.8 12.4 1.5 8.8 7.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator RhoGEF PF00621.20 ORY96599.1 - 2.3e-14 54.0 0.2 2.3e-14 54.0 0.2 1.8 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 ORY96599.1 - 0.13 12.8 1.6 9.5 6.8 0.0 3.5 4 0 0 4 4 4 0 PH domain DUF4663 PF15668.5 ORY96599.1 - 4.8 6.1 11.0 0.48 9.4 5.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4663) Methyltransf_16 PF10294.9 ORY96600.1 - 9.1e-30 103.7 0.0 1.4e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY96600.1 - 3.9e-06 26.8 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY96600.1 - 0.0056 16.3 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY96600.1 - 0.0061 16.0 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORY96600.1 - 0.0098 16.6 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96600.1 - 0.019 15.7 0.0 0.035 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96600.1 - 0.089 13.4 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.6 ORY96600.1 - 0.092 13.0 0.0 0.69 10.2 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_31 PF13847.6 ORY96600.1 - 0.19 11.5 0.1 0.47 10.2 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF2921 PF11145.8 ORY96601.1 - 0.00033 18.7 0.0 0.00036 18.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) TMEM154 PF15102.6 ORY96601.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family TMEM223 PF14640.6 ORY96601.1 - 0.02 15.0 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 CrgA PF06781.12 ORY96601.1 - 0.043 13.9 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein CrgA DUF5305 PF17231.2 ORY96601.1 - 0.049 13.0 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 ORY96601.1 - 0.053 12.3 0.0 0.053 12.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NicO PF03824.16 ORY96601.1 - 0.054 12.8 0.1 0.063 12.6 0.1 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein FeoB_associated PF12669.7 ORY96601.1 - 0.35 11.3 3.8 0.61 10.5 3.8 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4834 PF16118.5 ORY96601.1 - 0.57 11.2 3.5 0.3 12.1 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Ribosomal_L10 PF00466.20 ORY96602.1 - 2.9e-24 85.1 1.1 5.9e-24 84.1 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORY96602.1 - 5.3e-22 77.6 0.0 1.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 ORY96602.1 - 4.3e-21 75.3 5.5 2e-20 73.1 3.9 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein zf-trcl PF13451.6 ORY96603.1 - 0.89 9.5 4.9 0.35 10.8 1.9 1.9 2 0 0 2 2 2 0 Probable zinc-ribbon domain Sec2p PF06428.11 ORY96604.1 - 3.9e-13 49.2 9.6 3.9e-13 49.2 9.6 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p MscS_porin PF12795.7 ORY96604.1 - 0.027 14.0 26.2 0.039 13.5 26.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain MCPVI PF02993.14 ORY96604.1 - 0.065 13.1 3.1 0.069 13.0 2.2 1.4 1 1 0 1 1 1 0 Minor capsid protein VI Med9 PF07544.13 ORY96604.1 - 0.33 11.1 7.8 0.17 12.0 0.3 3.3 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 ORY96604.1 - 0.44 10.4 10.9 0.11 12.2 1.9 3.1 3 0 0 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.19 ORY96604.1 - 0.57 8.0 5.9 0.73 7.7 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 ORY96604.1 - 0.8 9.0 10.2 1.1 8.5 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 ORY96604.1 - 0.97 9.6 7.5 0.46 10.7 0.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 ORY96604.1 - 1.6 9.4 25.6 1.6 9.4 7.0 3.8 3 1 2 5 5 5 0 SlyX CNH PF00780.22 ORY96605.1 - 1e-58 199.2 0.0 1.9e-58 198.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 ORY96605.1 - 1.7e-37 128.5 0.0 3.5e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 ORY96605.1 - 8.4e-36 123.9 0.0 1.7e-35 122.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 ORY96605.1 - 1.7e-11 44.0 0.1 3.6e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 ORY96605.1 - 0.044 13.6 0.6 12 5.7 0.1 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain PH PF00169.29 ORY96605.1 - 0.09 13.3 0.0 1.4 9.5 0.0 2.8 1 1 0 1 1 1 0 PH domain SNase PF00565.17 ORY96606.1 - 0.071 13.6 0.2 0.071 13.6 0.2 2.1 1 1 1 2 2 2 0 Staphylococcal nuclease homologue zinc_ribbon_10 PF10058.9 ORY96607.1 - 2.3e-18 65.6 0.3 4e-18 64.9 0.3 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Lipoprotein_10 PF03202.13 ORY96607.1 - 0.0096 16.4 2.6 0.0096 16.4 2.6 1.6 2 0 0 2 2 2 1 Putative mycoplasma lipoprotein, C-terminal region Ras PF00071.22 ORY96608.1 - 6.5e-54 181.9 0.0 7.6e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY96608.1 - 1.1e-23 83.7 0.0 1.6e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY96608.1 - 8.1e-09 35.2 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY96608.1 - 8e-05 22.1 0.0 9.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY96608.1 - 0.00016 21.3 0.0 0.00063 19.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY96608.1 - 0.003 17.0 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY96608.1 - 0.0033 17.5 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY96608.1 - 0.0051 16.7 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MraZ PF02381.18 ORY96608.1 - 0.063 13.3 0.0 10 6.2 0.0 2.9 3 0 0 3 3 3 0 MraZ protein, putative antitoxin-like ABC_tran PF00005.27 ORY96608.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RRM_1 PF00076.22 ORY96609.1 - 6.4e-58 192.5 0.0 5.2e-21 74.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY96609.1 - 4.2e-09 36.2 0.0 9.4e-06 25.4 0.0 3.7 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORY96609.1 - 1.1e-07 31.8 0.0 0.24 11.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 ORY96609.1 - 8.9e-06 25.3 0.0 0.014 15.0 0.2 3.5 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 ORY96609.1 - 0.00011 22.5 0.3 0.3 11.3 0.1 3.4 3 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter SET_assoc PF11767.8 ORY96609.1 - 0.00055 19.5 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 ORY96609.1 - 0.0011 18.9 0.0 17 5.5 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 ORY96609.1 - 0.0027 17.6 0.6 0.65 10.0 0.2 2.9 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 ORY96609.1 - 0.031 14.3 0.0 11 6.1 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.11 ORY96609.1 - 0.081 13.0 0.0 55 3.9 0.0 3.4 3 1 0 3 3 3 0 RNA binding motif RRM_8 PF11835.8 ORY96609.1 - 0.098 12.9 0.0 5 7.4 0.0 2.5 2 1 0 2 2 2 0 RRM-like domain OB_RNB PF08206.11 ORY96609.1 - 0.16 11.7 0.5 18 5.1 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease B OB domain MBOAT PF03062.19 ORY96610.1 - 4.3e-40 138.1 16.4 4.3e-40 138.1 16.4 1.9 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY96610.1 - 0.0001 22.5 0.7 0.00029 21.1 0.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_tran_28_C PF04101.16 ORY96611.1 - 1.4e-27 96.8 0.0 1.5e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Phage_cap_P2 PF05125.12 ORY96611.1 - 0.0016 17.5 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Phage major capsid protein, P2 family Methyltransf_25 PF13649.6 ORY96612.1 - 4.4e-11 43.3 0.0 9.3e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96612.1 - 1e-10 41.7 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96612.1 - 1.3e-09 38.6 0.1 3.4e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96612.1 - 1.1e-07 31.8 0.0 2.7e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96612.1 - 9.5e-07 29.5 0.0 2.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY96612.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY96612.1 - 0.0038 16.7 0.0 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.12 ORY96612.1 - 0.011 15.4 0.0 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PEMT PF04191.13 ORY96613.1 - 5.8e-55 184.2 11.7 1.6e-32 112.1 1.9 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 ORY96613.1 - 0.002 17.9 0.1 0.0052 16.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 ORY96613.1 - 0.015 15.8 0.1 0.21 12.1 0.1 2.4 1 1 0 1 1 1 0 SKICH domain Apolipoprotein PF01442.18 ORY96613.1 - 0.037 13.9 1.6 0.068 13.0 1.6 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 ORY96613.1 - 0.097 13.3 1.1 0.24 12.0 0.6 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 ORY96613.1 - 5 7.1 5.3 12 5.9 1.6 2.8 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3340 PF11818.8 ORY96614.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.0 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Pkinase PF00069.25 ORY96615.1 - 2e-63 214.2 0.0 6.5e-63 212.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96615.1 - 6e-28 97.8 0.1 9.8e-21 74.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY96615.1 - 2.9e-07 29.8 0.0 3.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY96615.1 - 0.00064 19.7 3.0 0.025 14.5 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY96615.1 - 0.00079 18.8 0.9 0.0016 17.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY96615.1 - 0.0018 17.7 0.5 0.047 13.0 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 ORY96615.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 ORY96615.1 - 0.039 14.7 0.2 0.076 13.7 0.2 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain RIO1 PF01163.22 ORY96615.1 - 0.041 13.5 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 ORY96615.1 - 0.053 12.5 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 ORY96615.1 - 0.058 12.2 0.3 0.078 11.7 0.3 1.4 1 1 0 1 1 1 0 Fungal protein kinase NUFIP1 PF10453.9 ORY96615.1 - 0.13 12.1 2.0 0.2 11.5 0.5 2.0 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Y_phosphatase2 PF03162.13 ORY96616.1 - 2.2e-52 177.0 0.0 2.5e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY96616.1 - 0.0001 22.4 0.0 0.00034 20.6 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY96616.1 - 0.019 14.6 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 ORY96616.1 - 0.072 12.9 0.0 0.087 12.6 0.0 1.3 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CPSF_A PF03178.15 ORY96617.1 - 3.1e-89 299.5 0.0 7.2e-89 298.3 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 ORY96617.1 - 1.2e-34 119.8 0.1 2.7e-34 118.7 0.1 1.5 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Transmemb_17 PF09799.9 ORY96618.1 - 0.014 16.0 11.8 0.014 16.0 11.8 3.0 2 2 0 2 2 2 0 Predicted membrane protein Gemini_mov PF01708.16 ORY96618.1 - 0.12 12.2 0.2 0.12 12.2 0.2 3.4 3 1 1 4 4 4 0 Geminivirus putative movement protein TAP35_44 PF07265.11 ORY96618.1 - 0.18 11.9 0.2 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 HIG_1_N PF04588.13 ORY96618.1 - 6.2 7.1 9.0 1.8 8.8 0.8 2.9 2 0 0 2 2 2 0 Hypoxia induced protein conserved region zf-RING_2 PF13639.6 ORY96619.1 - 2.5e-08 34.1 4.4 8.1e-08 32.5 4.4 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY96619.1 - 2e-07 30.7 4.0 2e-07 30.7 4.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY96619.1 - 6.2e-07 29.3 3.0 6.2e-07 29.3 3.0 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY96619.1 - 0.00014 21.6 2.7 0.00038 20.2 2.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY96619.1 - 0.00036 20.8 5.3 0.0021 18.3 5.3 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY96619.1 - 0.00051 20.0 4.4 0.00051 20.0 4.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 ORY96619.1 - 0.00065 19.4 2.8 0.0017 18.0 2.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 ORY96619.1 - 0.0014 18.7 3.1 0.0039 17.3 3.1 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 ORY96619.1 - 0.0055 16.5 1.0 0.026 14.3 1.0 2.3 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 ORY96619.1 - 0.0056 16.5 9.6 0.012 15.4 6.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY96619.1 - 0.0076 16.4 1.9 0.0076 16.4 1.9 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Lantibiotic_a PF14867.6 ORY96619.1 - 0.0094 15.7 0.2 0.022 14.5 0.2 1.6 1 0 0 1 1 1 1 Lantibiotic alpha FYVE PF01363.21 ORY96619.1 - 0.011 15.8 3.1 0.034 14.3 3.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.6 ORY96619.1 - 0.05 13.5 4.5 0.25 11.2 4.3 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY96619.1 - 0.21 11.3 3.6 1.5 8.5 1.4 2.5 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORY96619.1 - 0.57 10.4 3.5 1.8 8.8 3.5 1.9 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 ORY96619.1 - 2 8.5 6.4 0.7 10.0 2.0 2.6 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger SH3_9 PF14604.6 ORY96620.1 - 8.9e-11 41.5 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY96620.1 - 2.8e-08 33.2 0.0 5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY96620.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Phage_HK97_TLTM PF06120.11 ORY96620.1 - 0.9 8.7 4.2 0.32 10.1 0.8 1.8 2 0 0 2 2 2 0 Tail length tape measure protein SBF_like PF13593.6 ORY96621.1 - 9.9e-83 278.0 13.9 1.2e-82 277.8 13.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 ORY96621.1 - 6.4e-08 32.5 6.5 6.4e-08 32.5 6.5 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family Mpv17_PMP22 PF04117.12 ORY96621.1 - 0.043 14.1 0.8 0.14 12.4 0.8 1.9 1 0 0 1 1 1 0 Mpv17 / PMP22 family TcpE PF12648.7 ORY96621.1 - 5.7 7.5 8.4 1.1 9.8 1.1 2.9 2 1 0 2 2 2 0 TcpE family PLDc_N PF13396.6 ORY96623.1 - 1.7e-11 43.8 4.1 1.7e-11 43.8 4.1 1.4 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal Glucos_trans_II PF14264.6 ORY96623.1 - 0.0097 15.3 2.0 0.011 15.1 2.0 1.0 1 0 0 1 1 1 1 Glucosyl transferase GtrII DUF4112 PF13430.6 ORY96623.1 - 0.014 15.6 0.1 0.019 15.2 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4112) DUF2207 PF09972.9 ORY96623.1 - 0.29 9.9 1.4 0.33 9.7 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PAS_3 PF08447.12 ORY96624.1 - 5.1e-15 55.5 0.4 3.6e-09 36.8 0.1 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORY96624.1 - 7.5e-14 51.7 0.3 3.6e-05 23.7 0.0 3.4 2 1 1 3 3 3 2 PAS fold PAS_11 PF14598.6 ORY96624.1 - 1.1e-08 35.2 1.2 0.00018 21.6 0.1 3.0 2 1 1 3 3 3 2 PAS domain PAS_9 PF13426.7 ORY96624.1 - 6.9e-08 32.7 0.0 0.00093 19.4 0.0 3.0 2 1 1 3 3 3 2 PAS domain PAS_4 PF08448.10 ORY96624.1 - 0.00016 21.9 0.0 0.045 14.0 0.0 2.6 2 1 1 3 3 3 2 PAS fold PAS_2 PF08446.11 ORY96624.1 - 0.015 16.0 0.1 1.9 9.2 0.0 2.3 2 0 0 2 2 2 0 PAS fold zf-C2H2 PF00096.26 ORY96625.1 - 2.4e-10 40.3 7.9 2.2e-05 24.7 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY96625.1 - 2.3e-07 31.0 11.9 0.00012 22.4 0.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY96625.1 - 2.7e-06 27.7 7.1 0.0034 18.1 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY96625.1 - 0.0038 17.5 0.6 0.0038 17.5 0.6 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY96625.1 - 0.0097 15.9 1.0 0.0097 15.9 1.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 ORY96625.1 - 0.013 15.8 0.7 0.024 14.9 0.7 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY96625.1 - 0.015 15.7 3.2 0.016 15.6 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 ORY96625.1 - 0.03 14.2 0.1 0.083 12.8 0.1 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 ORY96625.1 - 0.047 13.7 3.3 1.3 9.1 0.4 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.6 ORY96625.1 - 0.25 11.3 1.4 0.39 10.7 0.3 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORY96625.1 - 0.68 9.7 3.8 4.8 7.0 0.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 ORY96625.1 - 4.1 7.2 12.8 0.68 9.7 1.7 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain PBP_N PF17093.5 ORY96625.1 - 4.3 7.6 7.4 6.5 7.0 1.8 2.5 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus CN_hydrolase PF00795.22 ORY96626.1 - 5.6e-10 39.0 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Rieske PF00355.26 ORY96627.1 - 1.8e-11 43.8 0.0 3.8e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 ORY96627.1 - 2.6e-11 43.8 2.5 5.7e-11 42.7 2.5 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Ytp1 PF10355.9 ORY96628.1 - 7.9e-15 54.8 6.3 8.8e-14 51.4 6.3 2.6 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF962 PF06127.11 ORY96628.1 - 0.0096 16.0 0.0 0.075 13.1 0.0 2.3 2 2 0 2 2 2 1 Protein of unknown function (DUF962) DUF2976 PF11190.8 ORY96628.1 - 0.05 13.4 2.8 1.4 8.8 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) YtpI PF14007.6 ORY96628.1 - 7.3 6.8 7.3 4.8 7.4 0.0 3.7 4 0 0 4 4 4 0 YtpI-like protein Ribosomal_S17 PF00366.20 ORY96629.1 - 6.6e-28 96.6 4.5 8e-28 96.4 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ank_5 PF13857.6 ORY96630.1 - 1.4e-12 47.5 0.5 4.3e-07 30.1 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY96630.1 - 1e-10 41.9 1.3 3.9e-05 24.1 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY96630.1 - 1.6e-08 34.2 0.4 0.00013 22.1 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY96630.1 - 2.6e-08 34.3 0.3 8.3e-08 32.7 0.3 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY96630.1 - 3.6e-08 33.5 1.1 2.3e-05 24.6 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat SBP_bac_3 PF00497.20 ORY96630.1 - 0.12 11.8 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 YL1_C PF08265.11 ORY96631.1 - 1.2e-17 63.3 0.2 2.6e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 ORY96631.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 HIT zinc finger AAA PF00004.29 ORY96632.1 - 2.9e-42 144.2 0.0 5e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY96632.1 - 1.6e-10 40.8 0.3 3.1e-10 39.8 0.3 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY96632.1 - 3e-10 39.7 0.6 5.8e-10 38.8 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORY96632.1 - 2.6e-06 27.6 0.0 5.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORY96632.1 - 2.2e-05 23.7 0.0 3.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORY96632.1 - 3.8e-05 24.0 0.3 0.029 14.6 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY96632.1 - 0.00012 22.1 0.3 0.00092 19.2 0.2 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY96632.1 - 0.00015 22.2 0.1 0.0048 17.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY96632.1 - 0.00051 19.8 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 ORY96632.1 - 0.002 17.8 0.1 0.0056 16.3 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 ORY96632.1 - 0.0024 18.4 0.0 0.0061 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY96632.1 - 0.0066 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ORY96632.1 - 0.0066 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ORY96632.1 - 0.0069 15.7 0.4 0.24 10.7 0.1 2.6 2 1 0 3 3 3 1 KaiC AAA_14 PF13173.6 ORY96632.1 - 0.0076 16.3 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORY96632.1 - 0.027 14.7 0.5 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY96632.1 - 0.033 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 ORY96632.1 - 0.046 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 ORY96632.1 - 0.068 12.3 0.0 0.61 9.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 ORY96632.1 - 0.076 12.9 0.1 0.79 9.6 0.1 2.2 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 ORY96632.1 - 0.092 12.5 0.3 0.28 10.9 0.3 2.0 2 1 0 2 2 1 0 AAA domain DUF1128 PF06569.11 ORY96632.1 - 0.097 12.7 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) DUF2075 PF09848.9 ORY96632.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 ORY96632.1 - 0.12 12.7 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 ORY96632.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 ORY96632.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TatD_DNase PF01026.21 ORY96633.1 - 8.3e-49 166.3 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 ORY96633.1 - 0.0009 19.1 0.0 0.017 14.9 0.0 2.5 3 0 0 3 3 3 1 Amidohydrolase HAD_2 PF13419.6 ORY96634.1 - 6.8e-24 84.9 0.0 8.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY96634.1 - 5.8e-17 62.7 0.4 8e-15 55.7 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY96634.1 - 1.1e-07 31.8 0.1 2.5e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORY96634.1 - 0.0039 17.6 0.4 0.0059 17.0 0.4 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 ORY96634.1 - 0.015 15.3 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase WGR PF05406.15 ORY96634.1 - 0.033 14.2 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 WGR domain Stimulus_sens_1 PF13756.6 ORY96634.1 - 0.048 14.2 0.0 0.082 13.5 0.0 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain HAD_2 PF13419.6 ORY96635.1 - 5.2e-22 78.8 0.0 6.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY96635.1 - 1.6e-16 61.3 0.0 2.6e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY96635.1 - 8.8e-08 32.1 0.1 2.6e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORY96635.1 - 0.00027 21.4 0.0 0.00046 20.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Death PF00531.22 ORY96635.1 - 0.0074 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Death domain B3 PF02362.21 ORY96635.1 - 0.21 11.5 0.0 0.67 9.9 0.0 1.8 3 0 0 3 3 3 0 B3 DNA binding domain HSF_DNA-bind PF00447.17 ORY96636.1 - 4.8e-33 113.6 1.0 4.8e-33 113.6 1.0 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 ORY96636.1 - 0.071 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Ets-domain SNARE_assoc PF09335.11 ORY96637.1 - 5.2e-12 46.3 4.7 5.2e-12 46.3 4.7 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1749 PF08538.10 ORY96638.1 - 6.5e-65 219.2 0.0 7.5e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 ORY96638.1 - 4.6e-05 22.8 0.0 0.00094 18.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY96638.1 - 0.0075 15.9 0.0 0.015 15.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 ORY96638.1 - 0.0083 15.7 0.0 0.057 12.9 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Actin PF00022.19 ORY96639.1 - 1.1e-32 113.2 0.0 4.3e-31 107.9 0.0 2.6 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 ORY96639.1 - 5.9e-22 78.4 0.3 3.2e-18 66.1 0.1 3.1 2 1 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 ORY96639.1 - 7.6e-06 25.0 0.0 0.003 16.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORY96639.1 - 9.3e-06 26.0 0.0 4.9e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Cell division protein FtsA FEZ PF07763.13 ORY96639.1 - 1.7 8.3 7.3 2.6 7.7 1.0 2.9 3 0 0 3 3 3 0 FEZ-like protein E1-E2_ATPase PF00122.20 ORY96640.1 - 2.7e-46 157.4 5.5 2.7e-46 157.4 5.5 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY96640.1 - 9e-40 136.3 11.5 9e-40 136.3 11.5 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY96640.1 - 2.7e-23 83.4 1.0 5.8e-22 79.0 1.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY96640.1 - 5.5e-20 71.3 0.0 1.2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY96640.1 - 1.2e-17 63.3 0.0 3.5e-17 61.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY96640.1 - 2.3e-06 27.6 0.7 9.6e-05 22.2 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY96640.1 - 0.06 13.7 0.0 0.23 11.8 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1688 PF07958.11 ORY96641.1 - 3e-151 503.9 0.0 3.5e-151 503.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) bZIP_1 PF00170.21 ORY96642.1 - 1.1e-06 28.6 17.0 1.1e-06 28.6 17.0 3.2 4 1 0 4 4 2 1 bZIP transcription factor CCDC85 PF10226.9 ORY96642.1 - 9.3e-05 22.2 1.7 9.3e-05 22.2 1.7 1.6 2 0 0 2 2 2 1 CCDC85 family Rrn6 PF10214.9 ORY96642.1 - 0.00018 20.2 12.3 0.00021 19.9 12.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor bZIP_2 PF07716.15 ORY96642.1 - 0.0054 16.8 20.5 12 6.1 20.5 2.9 1 1 0 1 1 1 0 Basic region leucine zipper IFP_35_N PF07334.13 ORY96642.1 - 0.0094 16.0 0.1 0.0094 16.0 0.1 3.1 3 1 1 4 4 3 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF2937 PF11157.8 ORY96642.1 - 0.013 15.2 3.5 0.013 15.2 3.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) ASD2 PF08687.11 ORY96642.1 - 0.11 12.1 14.4 0.057 13.0 12.4 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 FPP PF05911.11 ORY96642.1 - 0.4 8.8 11.8 0.025 12.8 7.1 1.3 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil V_ATPase_I PF01496.19 ORY96642.1 - 0.54 8.1 5.8 0.71 7.7 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 ORY96642.1 - 0.67 10.6 6.6 0.22 12.2 3.6 1.8 2 0 0 2 2 1 0 Initiation control protein YabA DUF349 PF03993.12 ORY96642.1 - 0.82 10.0 10.9 3.5 8.0 10.9 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF4407 PF14362.6 ORY96642.1 - 1 8.7 6.7 1.1 8.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 ORY96642.1 - 1.3 9.4 12.5 1.8 9.0 12.5 1.2 1 0 0 1 1 1 0 AAA domain TSC22 PF01166.18 ORY96642.1 - 2 8.8 7.6 1.1e+02 3.2 7.6 2.4 1 1 0 1 1 1 0 TSC-22/dip/bun family MCU PF04678.13 ORY96642.1 - 2.2 8.3 8.9 3.4 7.7 8.5 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DivIC PF04977.15 ORY96642.1 - 3 7.7 12.9 1.5 8.6 10.1 1.9 1 1 1 2 2 2 0 Septum formation initiator Chibby PF14645.6 ORY96642.1 - 3.7 8.0 8.7 3.3 8.1 6.7 1.9 2 1 0 2 2 1 0 Chibby family FUSC PF04632.12 ORY96642.1 - 5.1 5.5 4.6 6.3 5.2 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 ORY96642.1 - 9.3 6.8 19.4 1 9.9 13.9 2.1 1 1 1 2 2 2 0 Cell division protein ZapB PRELI PF04707.14 ORY96643.1 - 1.9e-43 148.0 0.0 2.4e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Oxidored_molyb PF00174.19 ORY96644.1 - 2.5e-28 98.8 0.0 4.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY96644.1 - 5.6e-24 84.7 1.8 1.4e-23 83.4 1.8 1.7 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Ivy PF08816.11 ORY96644.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) ASTN_2_hairpin PF18577.1 ORY96645.1 - 0.0081 16.3 0.4 3.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Astrotactin-2 C-terminal beta-hairpin domain MFS_1 PF07690.16 ORY96646.1 - 1.7e-36 125.9 43.3 1.7e-36 125.9 43.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY96646.1 - 0.0043 16.0 4.0 0.0043 16.0 4.0 2.4 2 1 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 ORY96646.1 - 0.012 14.5 35.7 0.066 12.1 10.6 2.8 2 1 0 2 2 2 0 Sugar (and other) transporter PPR_2 PF13041.6 ORY96648.1 - 3.1e-58 193.8 22.4 2.4e-11 43.6 0.0 8.9 4 3 5 9 9 9 9 PPR repeat family PPR_3 PF13812.6 ORY96648.1 - 1.1e-42 143.9 11.2 2.2e-11 43.7 0.2 6.7 5 2 2 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY96648.1 - 3.5e-36 122.6 5.2 1.7e-08 34.0 0.0 8.8 9 0 0 9 9 9 7 PPR repeat PPR PF01535.20 ORY96648.1 - 1.6e-33 112.6 6.1 2.4e-06 27.4 0.1 8.6 8 0 0 8 8 8 7 PPR repeat PPR_long PF17177.4 ORY96648.1 - 1.4e-17 63.8 0.8 1.7e-07 30.8 0.3 3.6 1 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP DUF1651 PF07864.11 ORY96648.1 - 0.004 17.5 2.3 2.9 8.3 0.1 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1651) RPM2 PF08579.11 ORY96648.1 - 0.0067 16.8 3.7 1.1 9.7 0.1 3.9 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 ORY96648.1 - 0.0092 15.1 0.7 0.025 13.7 0.1 2.0 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway Ribosom_S12_S23 PF00164.25 ORY96649.1 - 7.5e-39 131.9 1.8 1.1e-38 131.4 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CortBP2 PF09727.9 ORY96649.1 - 0.046 13.6 0.3 0.058 13.3 0.3 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 ORC2 PF04084.14 ORY96650.1 - 1.1e-109 366.4 0.0 2.2e-109 365.4 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Fmp27 PF10344.9 ORY96650.1 - 0.2 9.7 4.8 0.44 8.6 4.2 1.7 1 1 1 2 2 2 0 Mitochondrial protein from FMP27 HLH PF00010.26 ORY96651.1 - 1.2e-14 54.0 2.8 2.4e-14 53.0 2.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 ORY96652.1 - 2.5e-13 49.8 1.3 5.5e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.6 ORY96652.1 - 0.052 14.4 0.1 0.068 14.0 0.1 1.1 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 GCP_C_terminal PF04130.13 ORY96653.1 - 7.5e-41 140.6 3.5 1.3e-40 139.8 3.5 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal SSP160 PF06933.11 ORY96653.1 - 0.092 10.9 9.5 0.12 10.5 9.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Complex1_30kDa PF00329.19 ORY96655.1 - 5.2e-46 156.2 0.0 7.3e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Castor1_N PF18700.1 ORY96655.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain TLD PF07534.16 ORY96656.1 - 1e-27 97.1 0.1 1.4e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 TLD PET117 PF15786.5 ORY96656.1 - 0.77 10.1 6.2 3.7 7.9 0.6 3.2 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial Glyco_hydro_18 PF00704.28 ORY96657.1 - 2e-74 251.1 1.8 2.6e-74 250.8 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 ORY96657.1 - 0.00012 22.0 9.4 0.00012 22.0 9.4 2.5 3 0 0 3 3 3 1 Carbohydrate binding domain (family 19) WW PF00397.26 ORY96657.1 - 0.013 15.5 0.3 0.032 14.3 0.3 1.7 1 0 0 1 1 1 0 WW domain CBM_14 PF01607.24 ORY96657.1 - 0.12 12.5 2.4 0.27 11.5 2.4 1.6 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain zf-GRF PF06839.12 ORY96658.1 - 6.4e-10 39.0 7.2 1.4e-09 37.9 7.2 1.6 1 0 0 1 1 1 1 GRF zinc finger SNF2_N PF00176.23 ORY96658.1 - 1.1e-06 27.6 0.0 1.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CoA_binding_2 PF13380.6 ORY96658.1 - 0.0047 17.4 0.0 0.013 16.0 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain T4SS_TraI PF16932.5 ORY96658.1 - 0.064 12.4 0.1 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Type IV secretory system, conjugal DNA-protein transfer NAD_kinase PF01513.21 ORY96659.1 - 1.9e-64 217.7 0.0 1.3e-63 214.9 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase SR-25 PF10500.9 ORY96659.1 - 0.21 11.2 5.0 0.38 10.3 5.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Meleagrin PF08189.11 ORY96659.1 - 0.43 10.3 5.7 0.2 11.4 2.9 1.9 2 0 0 2 2 2 0 Meleagrin/Cygnin family PHD PF00628.29 ORY96660.1 - 3.3e-08 33.3 9.9 8.7e-08 31.9 9.9 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY96660.1 - 0.031 13.8 0.4 0.078 12.6 0.4 1.7 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 ORY96660.1 - 0.052 13.6 1.6 0.24 11.5 1.6 2.2 1 0 0 1 1 1 0 CW-type Zinc Finger C1_1 PF00130.22 ORY96660.1 - 0.12 12.3 2.2 0.29 11.0 2.2 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 ORY96660.1 - 0.13 12.6 9.7 0.37 11.2 9.7 1.8 1 0 0 1 1 1 0 Ring finger domain PP2C PF00481.21 ORY96661.1 - 1e-21 77.7 0.0 2.7e-20 73.1 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C Dmrt1 PF12374.8 ORY96661.1 - 0.0056 17.1 1.8 3.2 8.3 0.0 2.5 2 0 0 2 2 2 2 Double-sex mab3 related transcription factor 1 Cytokin_check_N PF10407.9 ORY96661.1 - 0.045 13.7 0.4 17 5.5 0.0 2.9 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Fungal_trans PF04082.18 ORY96662.1 - 1.7e-29 102.7 0.2 9.3e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY96662.1 - 3.4e-08 33.5 8.4 6.7e-08 32.5 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_M PF01068.21 ORY96663.1 - 2.8e-66 223.1 2.4 5.2e-66 222.2 2.4 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY96663.1 - 1.4e-39 136.2 1.2 5.1e-39 134.4 1.2 1.9 1 1 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY96663.1 - 2.9e-26 91.9 0.0 2.2e-25 89.1 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ORY96663.1 - 2.4e-05 24.7 0.6 4.7e-05 23.8 0.6 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 ORY96663.1 - 0.037 14.1 0.3 3 7.9 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Gcd10p PF04189.13 ORY96664.1 - 2.8e-75 253.2 0.5 4.1e-75 252.7 0.5 1.2 1 0 0 1 1 1 1 Gcd10p family Rap_GAP PF02145.15 ORY96665.1 - 2.4e-54 183.7 0.0 4.1e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Integrase_H2C2 PF17921.1 ORY96665.1 - 5.9e-08 32.7 2.3 6.4e-08 32.6 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 ORY96665.1 - 0.038 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger AAA PF00004.29 ORY96667.1 - 1.8e-17 64.0 0.0 3.6e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 ORY96667.1 - 5.8e-13 49.2 0.3 5.8e-13 49.2 0.3 1.7 2 0 0 2 2 1 1 BCS1 N terminal AAA_7 PF12775.7 ORY96667.1 - 0.00061 19.4 0.0 0.0075 15.8 0.0 2.4 1 1 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 ORY96667.1 - 0.00062 19.0 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY96667.1 - 0.00086 19.9 0.0 0.0033 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY96667.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY96667.1 - 0.0015 18.9 0.0 0.025 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY96667.1 - 0.004 17.1 0.0 0.022 14.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ORY96667.1 - 0.005 16.7 3.7 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY96667.1 - 0.015 15.6 0.0 0.21 11.9 0.0 2.5 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORY96667.1 - 0.017 15.5 0.0 0.056 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase SATase_N PF06426.14 ORY96667.1 - 0.057 13.8 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal AAA_28 PF13521.6 ORY96667.1 - 0.063 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY96667.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY96667.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 ORY96667.1 - 1.9 7.2 9.8 3.2 6.4 9.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Paf1 PF03985.13 ORY96667.1 - 2.2 7.2 18.8 3.8 6.4 18.8 1.3 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 ORY96667.1 - 2.7 6.1 21.7 3.9 5.5 21.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORY96667.1 - 6 5.0 16.7 11 4.2 16.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 ORY96667.1 - 7 5.6 14.9 15 4.5 14.9 1.5 1 0 0 1 1 1 0 Pes-10 Tmemb_14 PF03647.13 ORY96669.1 - 1e-25 90.2 4.7 1.2e-25 90.1 4.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2198 PF09964.9 ORY96669.1 - 0.048 13.7 0.2 0.16 12.0 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Aim19 PF10315.9 ORY96669.1 - 0.056 13.7 1.2 0.09 13.1 1.2 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 Glyco_hydro_20 PF00728.22 ORY96670.1 - 7.7e-104 347.9 0.6 1e-103 347.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY96670.1 - 9.9e-26 91.0 0.0 2.1e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY96670.1 - 9.2e-08 32.9 0.0 3.7e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Tim17 PF02466.19 ORY96671.1 - 4.8e-06 26.9 0.1 1.2e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 ORY96671.1 - 0.03 14.9 0.5 2.6 8.7 0.0 2.6 3 0 0 3 3 3 0 N-terminal cysteine-rich region of Transmembrane protein 135 MRP-L28 PF09812.9 ORY96671.1 - 0.04 14.1 0.6 0.068 13.3 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF4752 PF15944.5 ORY96671.1 - 0.047 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) DIRP PF06584.13 ORY96671.1 - 0.11 12.7 0.7 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 DIRP WD40 PF00400.32 ORY96672.1 - 4e-21 74.9 8.3 0.00098 19.9 0.3 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96672.1 - 3.5e-06 27.2 0.1 1.9 8.9 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY96672.1 - 0.051 12.2 0.4 1.4 7.4 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PAC4 PF16093.5 ORY96672.1 - 3.3 8.0 5.1 0.6 10.3 0.5 2.2 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 DUF2358 PF10184.9 ORY96673.1 - 4.7e-11 43.0 0.0 8.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) MMU163 PF17119.5 ORY96673.1 - 2.2e-06 27.0 0.1 0.0095 15.1 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial protein up-regulated during meiosis Prefoldin PF02996.17 ORY96674.1 - 4.2e-19 68.6 0.3 7.8e-19 67.7 0.3 1.4 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 ORY96674.1 - 1.4e-11 45.1 8.6 1.6e-11 44.8 4.5 5.3 5 1 0 5 5 5 3 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 ORY96674.1 - 7.6e-10 38.7 0.1 2e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 Prefoldin subunit B56 PF01603.20 ORY96675.1 - 3.3e-172 573.2 5.1 3.7e-172 573.0 5.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Mac PF12464.8 ORY96675.1 - 0.044 14.0 0.2 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 Maltose acetyltransferase Sec7_N PF12783.7 ORY96675.1 - 0.049 13.5 1.3 0.14 12.0 0.2 2.3 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal BCS1_N PF08740.11 ORY96676.1 - 1.7e-18 67.3 0.0 3.7e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORY96676.1 - 6.2e-13 49.3 0.0 2.2e-06 28.1 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY96676.1 - 0.00026 20.8 0.0 0.00081 19.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY96676.1 - 0.00029 21.3 0.1 0.0021 18.5 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY96676.1 - 0.00089 19.3 0.0 0.0032 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY96676.1 - 0.0029 17.9 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 ORY96676.1 - 0.003 17.5 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY96676.1 - 0.0044 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY96676.1 - 0.005 16.7 3.6 0.026 14.3 3.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY96676.1 - 0.0052 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 ORY96676.1 - 0.006 16.5 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 ORY96676.1 - 0.0098 15.8 0.3 4.3 7.2 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ORY96676.1 - 0.011 16.2 0.0 0.055 13.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase PPV_E1_C PF00519.17 ORY96676.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_24 PF13479.6 ORY96676.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY96676.1 - 0.03 14.9 0.0 0.071 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY96676.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY96676.1 - 0.043 13.1 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 ORY96676.1 - 0.072 13.1 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY96676.1 - 0.089 13.1 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY96676.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 ORY96676.1 - 0.13 12.0 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 ORY96676.1 - 0.15 11.4 0.2 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY96676.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribonuc_red_sm PF00268.21 ORY96677.1 - 5.3e-120 400.1 1.0 6.6e-120 399.8 1.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain VTC PF09359.10 ORY96678.1 - 1.5e-69 234.5 0.5 2.5e-69 233.8 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 ORY96678.1 - 1.2e-14 55.1 26.3 1.2e-09 38.6 1.0 4.3 2 2 2 4 4 4 3 SPX domain DUF202 PF02656.15 ORY96678.1 - 1.1e-11 45.0 0.7 2.2e-11 44.0 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) AbiH PF14253.6 ORY96678.1 - 0.15 11.9 1.7 0.32 10.8 1.7 1.5 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH COOH-NH2_lig PF14395.6 ORY96678.1 - 0.17 11.1 0.6 0.32 10.2 0.0 1.6 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF5082 PF16888.5 ORY96678.1 - 0.52 10.6 6.4 0.089 13.1 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Cas_Cas6 PF01881.16 ORY96678.1 - 0.56 10.7 2.2 0.56 10.8 0.7 1.8 2 0 0 2 2 2 0 CRISPR associated protein Cas6 zf-C4H2 PF10146.9 ORY96678.1 - 0.72 10.1 3.7 1.8 8.8 2.4 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Remorin_C PF03763.13 ORY96678.1 - 5.6 6.9 5.5 0.77 9.7 0.9 1.9 2 0 0 2 2 2 0 Remorin, C-terminal region NMD3 PF04981.13 ORY96679.1 - 2.3e-86 289.2 1.5 3.2e-86 288.8 1.5 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 ORY96679.1 - 0.026 14.6 9.5 0.42 10.7 5.3 3.0 1 1 1 2 2 2 0 Double zinc ribbon CDT1 PF08839.11 ORY96679.1 - 0.062 13.6 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 DNA replication factor CDT1 like LSM PF01423.22 ORY96680.1 - 4.4e-19 67.9 0.2 7.3e-19 67.2 0.2 1.4 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY96680.1 - 0.0032 17.1 0.1 0.007 16.0 0.1 1.6 1 0 0 1 1 1 1 Hfq protein Methyltransf_16 PF10294.9 ORY96681.1 - 1.8e-20 73.4 0.0 3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 ORY96681.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY96681.1 - 2.1e-05 24.1 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORY96681.1 - 6.7e-05 23.5 0.0 0.00016 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY96681.1 - 0.00011 21.8 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ORY96681.1 - 0.00016 21.6 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96681.1 - 0.00032 21.4 0.1 0.0014 19.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain LSM PF01423.22 ORY96681.1 - 0.064 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 LSM domain Methyltransf_11 PF08241.12 ORY96681.1 - 0.081 13.6 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3074 PF11274.8 ORY96682.1 - 1e-28 100.6 0.1 1.5e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 ORY96682.1 - 2e-07 30.7 0.2 5.1e-07 29.3 0.0 1.6 1 1 0 2 2 2 1 START domain Itfg2 PF15907.5 ORY96683.1 - 4.1e-48 164.1 16.8 4.8e-21 75.1 3.2 6.6 3 2 2 5 5 5 5 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 ORY96683.1 - 0.00018 22.0 0.1 0.024 15.2 0.0 3.1 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ORY96683.1 - 0.0015 18.6 3.5 0.036 14.2 1.1 2.6 2 0 0 2 2 2 1 FG-GAP repeat BBS2_Mid PF14783.6 ORY96683.1 - 0.012 15.6 0.2 1.2 9.2 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 ORY96683.1 - 0.026 13.3 0.0 0.069 11.9 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Baculo_p26 PF04766.12 ORY96683.1 - 0.068 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein TFIIA PF03153.13 ORY96683.1 - 1.3 8.9 32.7 0.098 12.6 11.5 2.9 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.6 ORY96684.1 - 5.8e-20 71.8 0.0 9.1e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY96684.1 - 2.1e-17 63.6 0.0 6.2e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96684.1 - 2e-14 54.0 0.0 1.3e-13 51.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96684.1 - 6.1e-14 52.1 0.0 5.3e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96684.1 - 7.7e-13 49.0 0.0 1.5e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY96684.1 - 2.6e-09 37.4 0.0 4.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 ORY96684.1 - 8.5e-08 31.8 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 ORY96684.1 - 1.2e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ORY96684.1 - 3.6e-05 23.3 0.0 0.00047 19.7 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.14 ORY96684.1 - 0.00033 20.2 0.0 0.00062 19.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORY96684.1 - 0.00063 19.1 0.0 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 ORY96684.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 ORY96684.1 - 0.003 17.3 0.2 0.043 13.5 0.2 2.2 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 ORY96684.1 - 0.011 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Glyco_hydro_15 PF00723.21 ORY96686.1 - 5.1e-56 190.3 0.0 6.6e-55 186.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 FAA_hydrolase PF01557.18 ORY96687.1 - 5e-58 196.3 0.0 6.2e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ORY96687.1 - 6.6e-11 42.4 0.1 1.8e-10 40.9 0.2 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal RRM_1 PF00076.22 ORY96688.1 - 8.2e-25 86.4 0.3 7.9e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY96688.1 - 2.1e-08 33.9 0.0 5.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY96688.1 - 2.4e-05 23.9 0.0 0.023 14.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY96688.1 - 0.016 15.2 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY96688.1 - 0.064 13.3 0.3 0.35 10.9 0.3 2.0 2 0 0 2 2 2 0 RNA binding motif PAPS_reduct PF01507.19 ORY96689.1 - 7.6e-41 140.0 0.6 9.1e-41 139.8 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family DUF2951 PF11166.8 ORY96689.1 - 0.22 11.8 1.2 0.79 10.0 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) RRM_1 PF00076.22 ORY96690.1 - 9.6e-13 47.8 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2277 PF10041.9 ORY96690.1 - 0.01 16.2 0.0 0.034 14.5 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) RRM_5 PF13893.6 ORY96690.1 - 0.054 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY96690.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Herpes_pp85 PF04637.12 ORY96690.1 - 0.21 9.9 2.8 0.44 8.9 2.8 1.5 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PTPRCAP PF15713.5 ORY96691.1 - 0.0011 19.3 7.3 0.0018 18.5 7.3 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated RNA_pol_Rpc4 PF05132.14 ORY96691.1 - 0.0065 16.9 0.6 0.012 16.1 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 CDC45 PF02724.14 ORY96691.1 - 1.2 7.3 11.9 1.7 6.8 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORY96691.1 - 1.6 8.5 10.9 2.3 8.0 10.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 ORY96691.1 - 1.7 7.3 7.0 1.2 7.8 5.0 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 ORY96691.1 - 2.7 7.6 7.8 5.8 6.6 7.8 1.5 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 ORY96691.1 - 4.8 5.9 6.7 6.4 5.4 6.7 1.1 1 0 0 1 1 1 0 Presenilin MMS19_N PF14500.6 ORY96692.1 - 7.6e-96 320.7 6.6 2e-95 319.3 0.5 3.7 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 ORY96692.1 - 1.3e-81 274.9 11.0 2.7e-81 273.9 4.9 3.5 2 1 2 4 4 4 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 ORY96692.1 - 0.016 15.7 0.0 1 10.0 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Methyltransf_25 PF13649.6 ORY96693.1 - 1.6e-15 57.6 0.0 4.4e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96693.1 - 6.9e-13 48.8 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96693.1 - 1.7e-11 44.1 0.0 6e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96693.1 - 3.8e-10 40.3 0.0 7.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY96693.1 - 5.9e-09 36.6 0.0 1.3e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY96693.1 - 4e-05 23.1 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ORY96693.1 - 0.0031 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 ORY96693.1 - 0.006 15.9 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ORY96693.1 - 0.0061 16.0 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 ORY96693.1 - 0.0071 15.7 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 ORY96693.1 - 0.014 14.0 0.0 0.032 12.8 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 ORY96693.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 ORY96693.1 - 0.16 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Acyl-CoA_dh_1 PF00441.24 ORY96695.1 - 6.5e-33 114.1 0.2 1e-32 113.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY96695.1 - 2e-21 75.9 0.0 3.9e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY96695.1 - 3.4e-18 65.6 0.1 5.9e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY96695.1 - 8.2e-10 39.3 0.0 2.2e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY96695.1 - 5.1e-05 23.5 0.0 0.00043 20.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ribonuclease_P PF00825.18 ORY96696.1 - 2.1e-09 37.5 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P RAP1 PF07218.11 ORY96696.1 - 0.56 8.4 7.3 0.67 8.2 7.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2 PF00096.26 ORY96697.1 - 0.036 14.5 3.6 0.036 14.5 3.6 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3435 PF11917.8 ORY96697.1 - 0.12 11.3 6.9 0.19 10.6 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) zf-UBR PF02207.20 ORY96698.1 - 8.6e-20 70.7 13.7 8.6e-20 70.7 13.7 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 ORY96698.1 - 5.1e-11 42.2 0.0 1.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 ORY96698.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL MHB PF16525.5 ORY96698.1 - 1.7 9.0 4.4 16 5.9 0.6 3.7 4 0 0 4 4 4 0 Haemophore, haem-binding Histidinol_dh PF00815.20 ORY96698.1 - 5.3 5.9 6.2 9.6 5.1 6.2 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase Rgp1 PF08737.10 ORY96699.1 - 1.5e-101 340.6 5.3 1.3e-100 337.6 0.4 2.8 2 2 1 3 3 3 1 Rgp1 Arrestin_C PF02752.22 ORY96699.1 - 9.4e-07 29.4 0.0 0.052 14.0 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY96699.1 - 0.036 14.1 0.1 0.58 10.2 0.0 2.8 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain 4HBT_2 PF13279.6 ORY96700.1 - 8.8e-13 48.8 0.1 1.2e-12 48.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ORY96700.1 - 0.00024 20.5 0.1 0.00032 20.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase Pkinase PF00069.25 ORY96701.1 - 6.4e-75 251.9 0.0 7.5e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96701.1 - 7.7e-38 130.2 0.0 9.7e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY96701.1 - 1.4e-06 28.4 0.3 0.0031 17.5 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY96701.1 - 1.1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY96701.1 - 0.0099 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY96701.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 ORY96701.1 - 0.036 14.2 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family TetR_C_27 PF17935.1 ORY96701.1 - 0.061 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RhoGEF PF00621.20 ORY96702.1 - 6.6e-32 111.2 2.9 6.6e-32 111.2 2.9 2.0 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.11 ORY96702.1 - 2.4e-23 82.2 0.1 4.8e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 ORY96702.1 - 1e-14 54.8 3.8 1.3e-14 54.5 1.3 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PB1 PF00564.24 ORY96702.1 - 1.9e-11 43.7 0.1 5.4e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 ORY96702.1 - 0.0028 18.1 3.1 0.0082 16.6 0.4 2.9 3 0 0 3 3 3 1 PH domain DUF5087 PF17006.5 ORY96702.1 - 0.034 13.7 2.1 0.049 13.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5087) TPR_1 PF00515.28 ORY96703.1 - 1.1e-35 119.9 35.7 1.2e-08 34.5 0.5 8.0 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96703.1 - 3.6e-29 98.5 39.2 3.8e-05 23.5 0.4 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.31 ORY96703.1 - 2.1e-27 95.0 1.6 7.9e-27 93.2 1.6 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 ORY96703.1 - 6.8e-23 80.1 28.2 6.4e-05 22.5 2.6 8.1 6 1 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 ORY96703.1 - 3e-17 61.3 28.9 0.0027 17.8 0.2 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY96703.1 - 3e-17 63.0 29.9 3.9e-05 24.2 4.9 6.6 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORY96703.1 - 3.7e-17 62.6 25.1 4.9e-05 23.7 0.3 6.4 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96703.1 - 2.3e-14 52.9 26.7 0.14 13.1 1.1 8.3 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORY96703.1 - 1.1e-13 50.5 21.6 0.019 15.3 0.1 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY96703.1 - 1.8e-12 47.4 29.5 0.0043 17.3 0.1 6.9 4 2 2 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY96703.1 - 3.8e-09 36.6 26.9 0.0092 16.2 7.2 4.2 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 ORY96703.1 - 1.4e-06 27.5 22.6 0.0046 15.9 5.1 3.1 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 ORY96703.1 - 6.9e-06 26.1 15.3 0.0066 16.6 0.1 5.1 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY96703.1 - 1e-05 25.2 21.3 1.1 9.5 0.8 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY96703.1 - 0.00011 22.6 22.8 1.1 10.0 0.2 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY96703.1 - 0.063 13.2 0.2 0.063 13.2 0.2 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat ABC_ATPase PF09818.9 ORY96703.1 - 0.076 11.8 0.2 0.13 11.1 0.2 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SRP_TPR_like PF17004.5 ORY96703.1 - 0.35 10.9 15.8 0.57 10.2 6.6 3.9 3 2 1 4 4 4 0 Putative TPR-like repeat BTAD PF03704.17 ORY96703.1 - 0.59 10.6 18.6 5.4 7.4 5.5 3.1 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 ORY96703.1 - 0.72 10.0 14.2 48 4.1 1.2 5.9 4 2 2 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 ORY96703.1 - 1.4 9.0 13.9 0.9 9.6 1.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF627) SHNi-TPR PF10516.9 ORY96703.1 - 5.3 6.6 15.7 2.9 7.4 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR Alkyl_sulf_dimr PF14863.6 ORY96703.1 - 9.1 6.7 21.1 0.81 10.1 3.3 4.2 3 2 1 4 4 4 0 Alkyl sulfatase dimerisation Pkinase PF00069.25 ORY96704.1 - 1.2e-53 182.2 0.0 1.5e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96704.1 - 5.1e-38 130.8 0.0 6.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY96704.1 - 2.1e-07 30.1 0.0 3.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY96704.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 ORY96704.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CCDC24 PF15669.5 ORY96706.1 - 3.7 7.4 6.4 0.34 10.7 1.4 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family SPX PF03105.19 ORY96706.1 - 4.8 7.0 10.6 7.7 6.3 10.6 1.3 1 1 0 1 1 1 0 SPX domain Es2 PF09751.9 ORY96707.1 - 1.5e-47 163.4 24.8 1.5e-35 123.8 12.1 4.7 1 1 2 3 3 3 2 Nuclear protein Es2 Bromodomain PF00439.25 ORY96708.1 - 3e-16 59.2 0.0 7.7e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 ORY96708.1 - 3.2e-14 52.9 1.7 5.3e-09 35.8 0.8 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96708.1 - 4.2e-07 29.5 3.6 0.00055 19.3 1.8 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ORY96708.1 - 0.0044 16.4 0.4 0.011 15.1 0.4 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY96708.1 - 0.02 14.5 0.3 0.041 13.5 0.3 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 ORY96708.1 - 0.28 9.9 1.2 0.48 9.2 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase BRF1 PF07741.13 ORY96709.1 - 0.0018 18.5 2.8 0.0031 17.8 2.8 1.5 1 0 0 1 1 1 1 Brf1-like TBP-binding domain UL11 PF11094.8 ORY96709.1 - 2 8.4 3.6 0.86 9.5 0.1 2.0 2 0 0 2 2 2 0 Membrane-associated tegument protein GFO_IDH_MocA PF01408.22 ORY96710.1 - 9.4e-14 52.3 1.0 2.3e-12 47.8 1.0 2.3 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 ORY96710.1 - 0.002 18.4 0.1 0.035 14.4 0.2 2.6 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain CoA_binding_2 PF13380.6 ORY96710.1 - 0.023 15.2 0.0 0.058 13.9 0.0 1.6 2 0 0 2 2 2 0 CoA binding domain Toxin_28 PF08115.11 ORY96712.1 - 0.065 13.1 0.6 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 SFI toxin family Glyco_transf_15 PF01793.16 ORY96713.1 - 4.6e-112 374.5 6.7 5.7e-112 374.2 6.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ank PF00023.30 ORY96715.1 - 0.00071 19.9 0.1 0.002 18.5 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 ORY96715.1 - 0.0041 17.5 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 ORY96715.1 - 0.0085 16.7 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SUIM_assoc PF16619.5 ORY96715.1 - 0.13 12.3 3.4 0.97 9.5 3.6 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GAF_2 PF13185.6 ORY96717.1 - 1.1e-10 41.9 0.0 1.6e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ORY96717.1 - 1.5e-05 25.6 0.0 2e-05 25.2 0.0 1.2 1 1 0 1 1 1 1 GAF domain DSPc PF00782.20 ORY96718.1 - 6.7e-12 45.4 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 ORY96718.1 - 2.7e-05 23.9 0.1 8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF442 PF04273.13 ORY96718.1 - 0.0023 18.0 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative phosphatase (DUF442) PTPlike_phytase PF14566.6 ORY96718.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 ORY96718.1 - 0.039 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pyocin_S PF06958.12 ORY96719.1 - 1.7 9.2 6.2 8.8 6.9 2.1 2.0 1 1 1 2 2 2 0 S-type Pyocin adh_short PF00106.25 ORY96720.1 - 1.9e-36 125.4 0.1 2.5e-36 125.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase H2TH PF06831.14 ORY96720.1 - 1.1e-22 79.8 0.0 2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain adh_short_C2 PF13561.6 ORY96720.1 - 1.1e-21 77.5 0.3 1.8e-21 76.8 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY96720.1 - 8.6e-13 48.6 0.4 1.5e-12 47.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Fapy_DNA_glyco PF01149.24 ORY96720.1 - 0.00011 22.8 0.0 0.00021 21.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Eno-Rase_NADH_b PF12242.8 ORY96720.1 - 0.0026 17.5 0.1 0.0067 16.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 ORY96720.1 - 0.036 13.5 0.1 0.054 12.9 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FbpA PF05833.11 ORY96720.1 - 0.15 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PIP5K PF01504.18 ORY96722.1 - 1.9e-42 145.4 0.4 2.9e-34 118.5 0.6 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 ORY96722.1 - 8.5e-27 93.9 0.0 1.4e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 ORY96722.1 - 4.3e-17 62.0 15.8 1.2e-16 60.5 15.8 1.8 1 0 0 1 1 1 1 FYVE zinc finger Ribosomal_L15e PF00827.17 ORY96723.1 - 8.9e-89 296.3 9.6 1e-88 296.1 9.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Phosphoesterase PF04185.14 ORY96724.1 - 3.3e-83 279.8 0.7 5.4e-83 279.1 0.7 1.3 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 ORY96724.1 - 0.0034 16.8 0.1 0.053 12.9 0.1 2.2 1 1 0 1 1 1 1 Sulfatase Phosphoesterase PF04185.14 ORY96725.1 - 2.2e-30 106.0 6.1 2.5e-30 105.9 1.8 2.5 1 1 1 2 2 2 1 Phosphoesterase family Trypan_PARP PF05887.11 ORY96726.1 - 0.0042 17.1 59.7 0.0042 17.1 59.7 7.0 4 2 5 9 9 9 3 Procyclic acidic repetitive protein (PARP) Gcn1_N PF12074.8 ORY96727.1 - 1.3e-84 284.6 3.9 1.3e-84 284.6 3.9 5.0 7 1 1 8 8 8 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 ORY96727.1 - 1.8e-41 136.6 39.3 7.6e-05 22.6 0.0 24.4 27 1 1 28 28 26 8 HEAT repeat HEAT_EZ PF13513.6 ORY96727.1 - 7.4e-31 106.2 48.2 0.00067 20.1 0.1 21.0 19 3 3 22 22 21 7 HEAT-like repeat HEAT_2 PF13646.6 ORY96727.1 - 3.6e-29 101.0 51.2 1.5e-05 25.3 0.4 17.3 13 5 6 19 19 18 9 HEAT repeats Vac14_Fab1_bd PF12755.7 ORY96727.1 - 7.3e-16 58.6 0.9 0.0036 17.9 0.0 9.7 10 2 2 12 12 8 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 ORY96727.1 - 5.6e-15 55.5 0.4 0.018 14.6 0.0 7.6 7 1 1 8 8 8 3 CLASP N terminal Cnd1 PF12717.7 ORY96727.1 - 2.7e-14 53.5 9.9 0.0027 17.7 0.2 11.1 9 3 0 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY96727.1 - 8e-13 47.8 16.6 0.00032 19.4 2.6 10.1 7 4 1 10 10 10 4 Adaptin N terminal region ParcG PF10274.9 ORY96727.1 - 7.7e-11 42.4 0.8 0.019 15.1 0.0 6.8 4 2 1 6 6 6 2 Parkin co-regulated protein RIX1 PF08167.12 ORY96727.1 - 1.2e-07 31.7 8.6 0.00026 20.8 0.3 6.0 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 ORY96727.1 - 1.2e-06 28.6 0.4 2.6 7.9 0.0 8.3 9 2 1 10 10 9 1 Domain of unknown function (DUF3385) UME PF08064.13 ORY96727.1 - 0.00032 20.6 12.6 0.97 9.4 0.0 7.7 7 2 1 8 8 7 1 UME (NUC010) domain DRIM PF07539.12 ORY96727.1 - 0.0019 16.6 12.3 0.056 11.7 1.2 4.7 6 0 0 6 6 6 2 Down-regulated in metastasis MMS19_C PF12460.8 ORY96727.1 - 0.0082 15.3 20.0 0.61 9.1 0.0 9.1 7 3 2 10 10 10 1 RNAPII transcription regulator C-terminal ADSL_C PF10397.9 ORY96727.1 - 0.0085 16.6 2.6 6 7.5 0.1 4.7 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus TFCD_C PF12612.8 ORY96727.1 - 0.025 14.4 7.3 0.41 10.4 0.7 3.7 4 0 0 4 4 3 0 Tubulin folding cofactor D C terminal Phage_TAC_9 PF10876.8 ORY96727.1 - 0.039 14.0 0.2 21 5.2 0.0 4.2 4 0 0 4 4 3 0 Phage tail assemb.y chaperone protein, TAC FANCI_S2 PF14676.6 ORY96727.1 - 0.046 14.0 0.7 1.3 9.3 0.1 3.8 3 0 0 3 3 3 0 FANCI solenoid 2 L27 PF02828.16 ORY96727.1 - 0.056 13.2 4.2 5.2 6.9 0.1 4.7 6 0 0 6 6 6 0 L27 domain Sec7_N PF12783.7 ORY96727.1 - 0.24 11.3 3.5 1.6 8.7 0.0 3.9 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm PF00514.23 ORY96727.1 - 0.54 10.4 18.2 1.2e+02 2.9 0.0 10.0 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat MIT PF04212.18 ORY96728.1 - 7.3e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Allexi_40kDa PF05549.11 ORY96728.1 - 0.013 15.0 0.1 0.013 15.0 0.1 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein PRCC PF10253.9 ORY96728.1 - 0.015 16.1 4.0 0.04 14.7 4.0 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SUIM_assoc PF16619.5 ORY96728.1 - 0.34 11.0 6.7 1.1 9.4 6.7 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TMEM171 PF15471.6 ORY96728.1 - 0.49 9.3 3.2 0.84 8.6 3.2 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Mob1_phocein PF03637.17 ORY96729.1 - 6.1e-68 228.1 0.1 6.8e-68 228.0 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family CBS PF00571.28 ORY96731.1 - 8.5e-27 93.4 0.4 4e-05 24.0 0.0 4.4 4 0 0 4 4 4 4 CBS domain Pkinase PF00069.25 ORY96732.1 - 4e-68 229.6 0.0 6.8e-68 228.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96732.1 - 2.7e-45 154.7 0.0 4.5e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY96732.1 - 6.4e-22 77.7 0.2 2.5e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 ORY96732.1 - 1.1e-08 34.8 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY96732.1 - 7.4e-05 21.7 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY96732.1 - 0.00042 19.7 0.8 0.021 14.2 0.1 2.3 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY96732.1 - 0.006 15.6 0.4 0.017 14.1 0.4 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY96732.1 - 0.014 15.3 1.3 0.45 10.4 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY96732.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Usp PF00582.26 ORY96733.1 - 9.2e-08 32.7 0.0 4.3e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Universal stress protein family Acid_PPase PF12689.7 ORY96734.1 - 5.5e-53 179.3 0.0 6.3e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 ORY96734.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase TH1 PF04858.13 ORY96735.1 - 0.13 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 TH1 protein DNA_meth_N PF18284.1 ORY96735.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA methylase N-terminal domain CH PF00307.31 ORY96736.1 - 0.0016 18.6 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain BfiI_DBD PF18243.1 ORY96736.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain Pkinase PF00069.25 ORY96737.1 - 1.2e-63 215.0 0.0 2.2e-63 214.1 0.0 1.4 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96737.1 - 2.1e-36 125.6 0.0 3.6e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY96737.1 - 0.00024 20.0 0.0 0.00024 20.0 0.0 2.7 2 1 0 2 2 1 1 Fungal protein kinase Kdo PF06293.14 ORY96737.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPX PF03105.19 ORY96737.1 - 0.0068 16.4 17.9 0.0087 16.0 17.9 1.3 1 0 0 1 1 1 1 SPX domain Cwf_Cwc_15 PF04889.12 ORY96737.1 - 0.0088 15.8 3.4 0.019 14.7 0.3 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein APH PF01636.23 ORY96737.1 - 0.027 14.4 0.2 0.21 11.5 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY96737.1 - 0.036 13.4 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Roughex PF06020.11 ORY96737.1 - 0.21 10.7 7.7 0.34 10.0 7.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein FAM76 PF16046.5 ORY96737.1 - 0.48 9.7 11.6 0.14 11.5 1.6 2.1 2 0 0 2 2 2 0 FAM76 protein CCDC106 PF15794.5 ORY96737.1 - 0.97 9.1 19.8 1.9 8.2 3.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF2457 PF10446.9 ORY96737.1 - 1.5 7.8 20.0 2.3 7.3 20.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PAT1 PF09770.9 ORY96737.1 - 2.1 6.5 18.0 2.8 6.1 18.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 ORY96737.1 - 5.1 6.4 7.9 11 5.3 7.9 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein EIF_2_alpha PF07541.12 ORY96738.1 - 6.8e-37 126.1 0.1 1.6e-36 124.9 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 ORY96738.1 - 1.3e-13 51.0 1.7 2.9e-13 50.0 1.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 ORY96738.1 - 0.045 14.4 0.4 0.11 13.1 0.2 1.9 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 AstE_AspA PF04952.14 ORY96739.1 - 9.7e-26 90.5 0.0 1.5e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.11 ORY96739.1 - 7e-16 58.7 0.0 1.1e-11 45.0 0.0 2.3 1 1 1 2 2 2 2 HutD OPT PF03169.15 ORY96740.1 - 1.6e-157 525.8 43.9 1.9e-157 525.6 43.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MTHFR PF02219.17 ORY96741.1 - 1.1e-119 399.1 0.0 1.4e-119 398.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase OPT PF03169.15 ORY96743.1 - 2.4e-91 307.3 37.1 2.7e-91 307.1 37.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 ORY96743.1 - 0.11 11.9 1.3 0.37 10.1 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) TNFR_16_TM PF18422.1 ORY96743.1 - 0.28 11.2 4.0 0.82 9.7 2.8 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain LSM PF01423.22 ORY96744.1 - 1.9e-16 59.5 0.0 2.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY96744.1 - 0.032 14.3 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain RNA_pol_L_2 PF13656.6 ORY96745.1 - 2.3e-27 94.6 0.0 3.2e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORY96745.1 - 4.4e-08 32.4 0.0 7.2e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HAD_2 PF13419.6 ORY96747.1 - 5.7e-10 39.6 0.1 7.1e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY96747.1 - 6.3e-10 39.7 0.0 1.2e-09 38.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY96747.1 - 0.00021 21.3 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_60s PF00428.19 ORY96748.1 - 4.1e-27 94.6 9.9 4.9e-27 94.3 9.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 ORY96748.1 - 0.72 10.5 4.3 0.99 10.1 4.3 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Asp PF00026.23 ORY96749.1 - 2.5e-65 221.0 0.0 1.9e-64 218.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY96749.1 - 4.7e-14 53.0 0.2 1.5e-09 38.3 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY96749.1 - 1.8e-05 24.5 0.1 0.019 14.7 0.0 2.9 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY96749.1 - 0.0013 19.4 0.9 1.9 9.2 0.1 3.1 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY96749.1 - 0.0094 16.5 0.2 4.6 7.9 0.1 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease CHCH PF06747.13 ORY96750.1 - 0.00028 21.0 8.6 0.00028 21.0 8.6 1.7 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 ORY96750.1 - 0.00056 20.1 5.6 0.00069 19.8 5.6 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type FERM_N PF09379.10 ORY96750.1 - 0.0035 17.3 0.3 0.0052 16.7 0.3 1.3 1 0 0 1 1 1 1 FERM N-terminal domain Pet191_N PF10203.9 ORY96750.1 - 0.015 15.6 6.2 0.019 15.2 6.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TAP_C PF03943.13 ORY96750.1 - 0.24 11.1 2.5 0.16 11.6 1.1 1.5 1 1 1 2 2 2 0 TAP C-terminal domain Asp PF00026.23 ORY96751.1 - 9.6e-72 242.0 9.5 2.7e-71 240.6 9.5 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY96751.1 - 5.2e-11 43.1 11.4 1.7e-08 34.9 7.0 4.2 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY96751.1 - 0.0003 20.6 0.1 0.0011 18.7 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY96751.1 - 0.017 15.8 2.9 0.35 11.5 0.1 3.3 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 ORY96751.1 - 0.055 14.0 1.6 1.1 9.8 0.2 2.9 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease PCRF PF03462.18 ORY96752.1 - 7e-61 205.5 0.8 1.1e-60 204.9 0.1 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ORY96752.1 - 2.3e-41 140.4 4.6 4.4e-41 139.4 4.6 1.5 1 0 0 1 1 1 1 RF-1 domain YebO PF13974.6 ORY96752.1 - 0.0065 16.5 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 YebO-like protein DUF3573 PF12097.8 ORY96752.1 - 0.08 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Asp PF00026.23 ORY96753.1 - 6.9e-44 150.5 6.7 1.1e-21 77.6 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY96753.1 - 1.2e-06 28.9 1.2 1.2e-06 28.9 1.2 3.6 1 1 2 3 3 3 1 Xylanase inhibitor N-terminal ThiF PF00899.21 ORY96754.1 - 5.6e-38 130.7 0.0 7.6e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ORY96754.1 - 0.036 14.3 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Histone PF00125.24 ORY96755.1 - 7.6e-52 175.1 2.8 8.4e-52 175.0 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY96755.1 - 1.4e-05 25.4 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY96755.1 - 7.4e-05 22.8 0.4 0.00013 22.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY96755.1 - 0.00015 22.3 1.6 0.00019 22.0 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY96755.1 - 0.0015 18.8 0.1 0.0028 17.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY96755.1 - 0.016 15.3 0.2 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY96755.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated AA_kinase PF00696.28 ORY96756.1 - 9.4e-39 133.4 0.1 1.7e-38 132.6 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 ORY96756.1 - 6.9e-13 48.1 5.4 6.4e-06 25.8 0.1 3.2 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 ORY96756.1 - 8.6e-13 47.9 2.4 4.2e-08 32.9 0.4 2.5 2 0 0 2 2 2 2 ACT domain DUF562 PF04763.12 ORY96756.1 - 0.095 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF562) Nbl1_Borealin_N PF10444.9 ORY96756.1 - 0.2 11.3 1.8 0.45 10.2 1.8 1.6 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Patched PF02460.18 ORY96757.1 - 1.3e-85 288.2 16.0 7.7e-85 285.6 16.0 2.0 1 1 0 1 1 1 1 Patched family NPC1_N PF16414.5 ORY96757.1 - 1.8e-70 237.3 9.0 1.8e-70 237.3 6.7 2.0 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 ORY96757.1 - 1.3e-51 174.5 5.6 1.3e-51 174.5 5.6 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 ORY96757.1 - 0.13 9.9 16.7 0.26 8.9 16.7 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.15 ORY96757.1 - 1.6 7.6 21.7 0.0066 15.4 4.9 2.5 2 1 0 2 2 2 0 MMPL family PRP38 PF03371.15 ORY96758.1 - 4.7e-62 208.9 0.4 5.5e-62 208.7 0.4 1.0 1 0 0 1 1 1 1 PRP38 family CAP_GLY PF01302.25 ORY96761.1 - 6.4e-28 96.6 0.3 1.2e-27 95.7 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 ORY96761.1 - 5.5e-23 81.2 0.0 1.5e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 ORY96761.1 - 0.0014 18.4 0.0 0.0066 16.2 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin family Peptidase_M49 PF03571.15 ORY96762.1 - 3.1e-233 775.1 0.1 5.8e-233 774.3 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M49 Homeodomain PF00046.29 ORY96766.1 - 5.3e-17 61.4 3.1 6e-17 61.2 3.1 1.1 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORY96766.1 - 0.0015 18.3 0.5 0.0044 16.8 0.1 2.0 2 1 0 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.11 ORY96766.1 - 0.0042 16.9 0.9 0.0048 16.8 0.1 1.5 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORY96766.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT BrkDBD PF09607.10 ORY96766.1 - 0.11 12.3 0.2 10 6.0 0.0 2.1 1 1 1 2 2 2 0 Brinker DNA-binding domain DUF4451 PF14616.6 ORY96767.1 - 7.7e-21 74.6 4.6 1.3e-20 73.8 4.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF4887 PF16228.5 ORY96767.1 - 3.7 7.7 13.7 7.8 6.7 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DEAD PF00270.29 ORY96768.1 - 1.7e-37 128.9 0.0 2.8e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY96768.1 - 1.8e-27 95.8 0.2 7.8e-25 87.4 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY96768.1 - 1.8e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY96768.1 - 0.0081 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 ORY96768.1 - 0.042 14.4 0.8 0.11 13.1 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Metalloenzyme PF01676.18 ORY96769.1 - 3.4e-78 262.4 0.0 4e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 ORY96769.1 - 5.1e-77 258.1 0.0 7.5e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 ORY96769.1 - 3e-06 27.1 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY96769.1 - 0.0016 17.9 0.0 0.0061 16.0 0.0 2.0 1 1 1 2 2 2 1 Sulfatase PglZ PF08665.12 ORY96769.1 - 0.017 15.3 0.0 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 PglZ domain Alk_phosphatase PF00245.20 ORY96769.1 - 0.017 14.1 0.1 0.077 11.9 0.0 2.1 3 0 0 3 3 3 0 Alkaline phosphatase Fructosamin_kin PF03881.14 ORY96770.1 - 2e-82 276.7 0.0 2.3e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ORY96770.1 - 5.4e-14 52.7 0.0 6.9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family HhH-GPD PF00730.25 ORY96771.1 - 9.8e-20 71.0 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY96771.1 - 3.1e-06 26.8 0.2 1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ORY96771.1 - 0.0005 20.3 5.6 0.00093 19.5 5.6 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Put_Phosphatase PF06888.12 ORY96772.1 - 4.3e-50 170.3 0.1 5e-50 170.1 0.1 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 ORY96772.1 - 5.4e-10 40.0 0.3 1.6e-09 38.4 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY96772.1 - 4.5e-05 23.8 0.4 0.00011 22.5 0.0 1.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY96772.1 - 0.0015 18.6 2.0 0.014 15.5 1.8 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DAGAT PF03982.13 ORY96773.1 - 2.6e-99 331.9 0.0 3e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PqiA PF04403.13 ORY96773.1 - 0.0033 17.3 0.7 0.0052 16.6 0.7 1.2 1 0 0 1 1 1 1 Paraquat-inducible protein A DUF2852 PF11014.8 ORY96773.1 - 0.17 12.1 0.6 0.35 11.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4018 PF13210.6 ORY96774.1 - 0.018 14.8 0.4 0.019 14.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) DUF4703 PF15775.5 ORY96774.1 - 3.8 7.3 5.5 4.8 6.9 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Mito_carr PF00153.27 ORY96776.1 - 2.9e-65 216.2 1.3 2.1e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chal_sti_synt_C PF02797.15 ORY96776.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Glyco_hydro_28 PF00295.17 ORY96777.1 - 1.9e-32 112.6 4.5 2.5e-32 112.2 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 ORY96777.1 - 2.2e-06 27.7 4.7 2.2e-06 27.7 4.7 2.3 1 1 1 2 2 2 1 Pectate lyase superfamily protein Ribosomal_S25 PF03297.15 ORY96778.1 - 4.5e-38 129.5 0.4 6e-38 129.1 0.4 1.2 1 0 0 1 1 1 1 S25 ribosomal protein BioT2 PF15368.6 ORY96778.1 - 0.0054 16.7 0.2 0.0061 16.5 0.2 1.2 1 0 0 1 1 1 1 Spermatogenesis family BioT2 AIPR PF10592.9 ORY96778.1 - 0.014 15.1 0.3 0.021 14.4 0.2 1.5 1 1 1 2 2 2 0 AIPR protein HTH_24 PF13412.6 ORY96778.1 - 0.016 14.8 0.2 0.024 14.2 0.2 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ORY96778.1 - 0.021 14.7 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 MarR family MoaC PF01967.21 ORY96779.1 - 2.2e-51 173.5 1.9 3.1e-51 173.0 1.9 1.2 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 ORY96779.1 - 4.1e-37 127.0 0.0 7.5e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 ORY96779.1 - 5.7e-33 114.7 0.0 1.4e-32 113.3 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 ORY96779.1 - 8.1e-07 29.4 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORY96779.1 - 0.0073 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain BK_channel_a PF03493.18 ORY96781.1 - 1.3e-14 54.1 2.1 7.5e-14 51.7 0.1 2.8 2 1 1 3 3 3 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORY96781.1 - 3.8e-05 23.6 3.0 3.8e-05 23.6 3.0 2.3 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 ORY96781.1 - 0.00064 20.0 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Castor_Poll_mid PF06241.12 ORY96781.1 - 0.00076 19.4 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel MHYT PF03707.16 ORY96781.1 - 0.61 10.3 2.8 1.9 8.7 2.8 1.9 1 1 0 1 1 1 0 Bacterial signalling protein N terminal repeat Cu-oxidase_2 PF07731.14 ORY96782.1 - 9.9e-18 64.2 5.7 2.8e-11 43.3 5.8 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY96782.1 - 1.2e-10 41.4 4.3 1.8e-10 40.9 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase zf-CCCH_4 PF18044.1 ORY96783.1 - 1.1e-13 50.6 7.7 6e-07 29.1 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY96783.1 - 5.3e-11 42.2 17.3 1.7e-06 27.9 3.4 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORY96783.1 - 5.4e-10 38.9 7.5 0.0002 21.1 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 ORY96783.1 - 7.6e-06 26.1 1.7 2.4e-05 24.5 1.7 1.9 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 ORY96783.1 - 1.2e-05 25.9 12.4 0.0033 18.1 0.6 3.1 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 ORY96783.1 - 0.028 14.9 3.3 0.028 14.9 3.3 2.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CTP_transf_1 PF01148.20 ORY96784.1 - 0.0041 16.9 1.6 0.0058 16.4 1.6 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family LuxC PF05893.14 ORY96785.1 - 0.029 13.4 0.1 0.033 13.2 0.1 1.0 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PAS_3 PF08447.12 ORY96785.1 - 0.054 13.8 0.2 0.15 12.3 0.1 1.8 1 1 1 2 2 2 0 PAS fold HEPN_RES_NTD1 PF18870.1 ORY96785.1 - 0.069 13.4 0.4 0.088 13.0 0.3 1.2 1 1 0 1 1 1 0 HEPN/RES N-terminal domain 1 LRR_9 PF14580.6 ORY96786.1 - 1.3e-61 207.2 5.8 1.7e-61 206.7 5.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORY96786.1 - 3.6e-09 36.7 14.0 3.9e-05 23.9 1.2 3.9 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY96786.1 - 2.7e-05 23.8 7.8 0.00036 20.2 5.1 3.2 1 1 2 3 3 3 3 Leucine rich repeat PspB PF06667.12 ORY96786.1 - 0.077 13.1 0.2 0.25 11.4 0.2 1.8 1 0 0 1 1 1 0 Phage shock protein B MFS_1 PF07690.16 ORY96788.1 - 3.5e-34 118.3 49.1 6.6e-29 100.9 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 ORY96788.1 - 0.002 17.9 1.5 0.43 10.4 0.0 2.3 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Wzz PF02706.15 ORY96788.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.1 3 1 0 3 3 3 0 Chain length determinant protein Halogen_Hydrol PF10112.9 ORY96788.1 - 2 8.4 3.8 2.2 8.2 0.0 2.6 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein COBRA1 PF06209.13 ORY96789.1 - 7.6e-28 97.6 6.2 2e-27 96.2 6.2 1.6 1 1 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Alkyl_sulf_dimr PF14863.6 ORY96789.1 - 0.021 15.3 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation 7TMR-HDED PF07697.11 ORY96789.1 - 0.091 12.9 0.1 0.36 10.9 0.0 1.8 1 1 1 2 2 2 0 7TM-HD extracellular ACDC PF14733.6 ORY96789.1 - 1.6 9.1 4.3 25 5.3 0.3 3.7 3 1 0 3 3 3 0 AP2-coincident C-terminal DUF1729 PF08354.10 ORY96790.1 - 1.6e-153 510.8 0.0 2.7e-153 510.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 ORY96790.1 - 1.4e-71 240.1 0.0 3.1e-71 239.0 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 ORY96790.1 - 2.5e-71 240.8 0.0 9.3e-71 238.9 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain FAS_I_H PF18314.1 ORY96790.1 - 4.1e-68 229.0 0.0 8.1e-68 228.1 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain FAS_meander PF17951.1 ORY96790.1 - 1.8e-46 157.6 0.0 5.1e-46 156.1 0.0 1.9 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 ORY96790.1 - 3.5e-32 112.1 0.0 7.1e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 ORY96790.1 - 5.6e-30 103.4 0.0 2.1e-29 101.6 0.0 2.0 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 ORY96790.1 - 7.3e-28 97.2 0.3 1.9e-27 95.8 0.3 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta ketoacyl-synt PF00109.26 ORY96790.1 - 3e-21 76.1 0.6 1.9e-20 73.5 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MaoC_dehydrat_N PF13452.6 ORY96790.1 - 1.6e-17 63.8 0.0 5e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase ACPS PF01648.20 ORY96790.1 - 6.2e-16 58.6 0.0 1.7e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 ORY96790.1 - 1.5e-11 44.3 0.0 4.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 ORY96790.1 - 1.4e-05 24.6 0.0 4.3e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 ORY96790.1 - 0.0045 16.4 0.2 0.01 15.2 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 ORY96790.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 KR domain DUF3597 PF12200.8 ORY96790.1 - 2.1 8.9 4.4 7.8 7.0 4.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF3627 PF12299.8 ORY96790.1 - 6.6 6.9 5.9 0.94 9.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) RRM_1 PF00076.22 ORY96791.1 - 2.6e-14 52.8 0.0 4.2e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ORY96791.1 - 4.8e-07 30.2 6.6 4.8e-07 30.2 6.6 4.8 3 1 1 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.6 ORY96791.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 ORY96792.1 - 1.7e-11 44.3 5.3 3e-11 43.5 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY96792.1 - 4.9e-09 35.9 5.3 9.7e-09 34.9 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY96792.1 - 1.4e-08 34.5 4.8 2.5e-08 33.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY96792.1 - 2.3e-07 30.7 3.6 4.1e-07 29.9 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY96792.1 - 2.8e-05 24.1 1.3 2.8e-05 24.1 1.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY96792.1 - 3.2e-05 24.1 6.6 0.00023 21.4 6.6 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORY96792.1 - 4.3e-05 23.2 2.7 4.3e-05 23.2 2.7 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 ORY96792.1 - 0.00018 21.3 6.9 0.00032 20.5 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY96792.1 - 0.0052 16.6 8.2 0.011 15.6 8.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY96792.1 - 0.0053 16.5 6.3 0.01 15.6 6.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY96792.1 - 0.026 14.7 7.0 0.062 13.5 7.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORY96792.1 - 0.24 11.5 4.7 1 9.5 4.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 ORY96792.1 - 0.79 9.9 5.7 1.8 8.7 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CNH PF00780.22 ORY96793.1 - 2.8e-51 174.8 0.0 4.2e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY96793.1 - 4.2e-38 131.4 0.1 6.6e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY96793.1 - 7.2e-20 71.5 0.0 1.4e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 ORY96793.1 - 0.0016 18.3 0.2 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 PH domain PH PF00169.29 ORY96793.1 - 0.059 13.9 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 PH domain adh_short PF00106.25 ORY96794.1 - 1.7e-32 112.5 0.1 1.4e-31 109.4 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY96794.1 - 3e-21 76.0 0.0 1.5e-20 73.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY96794.1 - 4.6e-07 29.9 0.1 7.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY96794.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ORY96794.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 ORY96794.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY96794.1 - 0.028 14.3 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding p450 PF00067.22 ORY96795.1 - 1.9e-100 336.8 0.0 2.7e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORY96795.1 - 7.6e-36 123.8 0.0 4.8e-35 121.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY96795.1 - 1.6e-26 93.3 0.4 2.9e-26 92.4 0.4 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY96795.1 - 1.4e-17 64.3 0.0 2.9e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain AMP-binding PF00501.28 ORY96796.1 - 5.3e-79 265.8 0.1 7e-79 265.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY96796.1 - 5.6e-23 81.7 0.0 1.2e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORY96796.1 - 7e-12 45.1 0.3 6.8e-11 41.9 0.1 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Hydrolase_4 PF12146.8 ORY96797.1 - 9.3e-15 54.5 0.1 9.9e-09 34.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY96797.1 - 2e-11 44.0 0.3 3.4e-05 23.6 0.4 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY96797.1 - 5.6e-08 33.7 6.2 9.3e-07 29.7 5.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORY96797.1 - 0.0018 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 ORY96797.1 - 0.011 15.9 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 ORY96797.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 ORY96797.1 - 0.02 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 ORY96797.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Defensin_beta PF00711.19 ORY96797.1 - 0.13 12.3 1.8 0.21 11.6 1.8 1.3 1 0 0 1 1 1 0 Beta defensin BAAT_C PF08840.11 ORY96797.1 - 0.17 11.8 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal mRNA_triPase PF02940.15 ORY96798.1 - 6.8e-57 192.7 1.1 8.4e-57 192.4 1.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Ras PF00071.22 ORY96799.1 - 3.1e-55 186.2 0.0 3.6e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY96799.1 - 1.5e-21 76.8 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY96799.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY96799.1 - 0.005 16.3 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Peroxin-3 PF04882.12 ORY96801.1 - 3.8e-128 428.4 3.4 4.9e-128 428.1 3.4 1.1 1 0 0 1 1 1 1 Peroxin-3 Presenilin PF01080.17 ORY96801.1 - 9e-05 21.4 7.0 0.00012 21.0 7.0 1.2 1 0 0 1 1 1 1 Presenilin Asp-B-Hydro_N PF05279.11 ORY96801.1 - 0.29 11.2 27.0 0.54 10.3 27.0 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Zip PF02535.22 ORY96801.1 - 0.32 10.2 2.8 0.45 9.7 2.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 ORY96801.1 - 0.47 9.2 11.4 0.64 8.7 11.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 ORY96801.1 - 1.2 9.4 11.1 1.7 8.9 11.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.7 ORY96801.1 - 2.9 5.9 16.8 4.2 5.4 16.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.6 ORY96801.1 - 3.1 6.5 12.9 4.5 5.9 12.9 1.2 1 0 0 1 1 1 0 Raftlin GREB1 PF15782.5 ORY96801.1 - 5.9 3.9 9.7 7.4 3.6 9.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 ORY96801.1 - 6.2 5.4 6.6 8.9 4.9 6.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cu-oxidase PF00394.22 ORY96802.1 - 1.1e-34 119.8 0.0 3.2e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY96802.1 - 2.9e-29 101.5 0.2 2.9e-29 101.5 0.2 4.7 4 2 1 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY96802.1 - 8.3e-23 80.6 16.1 1.9e-21 76.2 6.3 3.8 4 2 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.6 ORY96802.1 - 0.013 15.6 0.0 50 4.1 0.0 3.4 3 0 0 3 3 3 0 Cupredoxin-like domain MOSC_N PF03476.16 ORY96803.1 - 3.5e-27 94.7 0.0 5.4e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 ORY96803.1 - 1.8e-20 73.3 0.0 5.6e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 MOSC domain Acetyltransf_1 PF00583.25 ORY96804.1 - 9.6e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY96804.1 - 6.8e-09 36.0 0.0 1.2e-08 35.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY96804.1 - 8.4e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY96804.1 - 5.3e-05 23.1 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY96804.1 - 0.00046 20.9 0.0 0.00055 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY96804.1 - 0.0025 17.9 0.0 0.007 16.5 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 ORY96804.1 - 0.0036 17.4 0.0 0.0074 16.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.31 ORY96805.1 - 3.1e-44 148.9 13.5 2.4e-14 53.2 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY96805.1 - 6.3e-36 122.4 8.7 4.9e-16 58.7 0.6 3.7 2 1 2 4 4 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY96805.1 - 0.00029 21.0 1.6 0.07 13.3 0.6 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 ORY96805.1 - 0.0013 18.8 6.5 0.51 10.5 0.7 3.4 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_8 PF15909.5 ORY96805.1 - 0.0078 16.5 0.1 0.023 15.0 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY96805.1 - 0.022 15.2 0.3 0.022 15.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain SLIDE PF09111.10 ORY96805.1 - 0.025 14.6 0.1 13 5.9 0.0 2.9 1 1 2 3 3 3 0 SLIDE zf-C2H2_aberr PF17017.5 ORY96805.1 - 0.027 14.6 2.1 1.6 8.9 0.2 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY96805.1 - 0.028 14.8 7.4 0.7 10.5 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY96805.1 - 0.22 12.2 7.8 9.8 6.9 0.0 4.0 4 0 0 4 4 4 0 FOXP coiled-coil domain DUF4551 PF15087.6 ORY96805.1 - 4.5 6.0 5.7 0.55 9.0 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) zf-C2H2_4 PF13894.6 ORY96805.1 - 8.1 7.6 16.7 1.8 9.6 0.1 4.4 5 0 0 5 5 4 0 C2H2-type zinc finger Anp1 PF03452.14 ORY96806.1 - 6.3e-51 173.3 0.0 7.8e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Porin_3 PF01459.22 ORY96807.1 - 1.2e-70 238.1 4.5 1.3e-70 237.9 4.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tox-REase-2 PF15646.6 ORY96807.1 - 0.06 13.5 0.0 1.7 8.9 0.0 2.1 1 1 0 2 2 2 0 Restriction endonuclease fold toxin 2 Tubulin PF00091.25 ORY96808.1 - 1.1e-54 185.6 0.0 1.6e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY96808.1 - 4.6e-50 169.0 0.0 7.5e-50 168.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY96808.1 - 0.00022 20.9 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain TGT PF01702.18 ORY96809.1 - 6.8e-150 499.1 0.0 7.9e-150 498.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M13_N PF05649.13 ORY96810.1 - 2.4e-83 280.9 1.0 3.3e-83 280.5 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY96810.1 - 2.4e-64 216.7 0.7 4e-64 216.0 0.7 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 ORY96810.1 - 0.036 13.8 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 DASH_Dad1 PF08649.10 ORY96811.1 - 1.4e-12 47.6 0.0 1.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 ORY96811.1 - 0.00042 20.2 0.1 0.0005 20.0 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad2 PF08654.10 ORY96811.1 - 0.0022 18.4 0.2 0.0033 17.8 0.2 1.3 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Hsk3 PF08227.11 ORY96811.1 - 0.0023 18.3 6.1 0.0034 17.7 6.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF1043 PF06295.12 ORY96811.1 - 0.028 14.4 0.4 0.034 14.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DELLA PF12041.8 ORY96811.1 - 0.056 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal GAGBD PF16828.5 ORY96811.1 - 0.076 13.1 0.0 0.082 13.0 0.0 1.0 1 0 0 1 1 1 0 GAG-binding domain on surface antigen YEATS PF03366.16 ORY96812.1 - 7.9e-34 115.5 0.9 1.4e-33 114.7 0.9 1.4 1 0 0 1 1 1 1 YEATS family DUF5102 PF17104.5 ORY96813.1 - 8.9e-41 140.8 0.2 1.5e-40 140.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Hyaluronidase_1 PF07212.11 ORY96813.1 - 0.02 14.2 0.3 0.043 13.1 0.0 1.6 2 0 0 2 2 2 0 Hyaluronidase protein (HylP) Clathrin_bdg PF15045.6 ORY96813.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking FEZ PF07763.13 ORY96813.1 - 0.27 10.9 2.3 0.73 9.5 2.3 1.9 1 1 0 1 1 1 0 FEZ-like protein NDUFA12 PF05071.16 ORY96814.1 - 4.5e-26 91.5 0.6 5.4e-26 91.3 0.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DDHD PF02862.17 ORY96815.1 - 1.6e-43 149.5 0.0 3.3e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 DDHD domain WWE PF02825.20 ORY96815.1 - 0.00032 21.2 0.1 0.42 11.2 0.1 2.8 2 0 0 2 2 2 2 WWE domain Abhydrolase_6 PF12697.7 ORY96815.1 - 0.012 16.2 0.3 0.05 14.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family TssO PF17561.2 ORY96815.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO Arrestin_N PF00339.29 ORY96816.1 - 2.8e-10 40.4 0.0 5.6e-08 33.0 0.0 3.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY96816.1 - 1.5e-08 35.1 0.0 4.5e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY96816.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.8 2 1 0 2 2 2 0 Arrestin_N terminal like Cwf_Cwc_15 PF04889.12 ORY96816.1 - 1.5 8.5 10.4 0.043 13.5 2.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CHORD PF04968.12 ORY96817.1 - 2.5e-54 181.8 20.2 4.9e-27 94.4 7.7 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 ORY96817.1 - 4.9e-15 56.3 2.5 7.9e-15 55.6 2.5 1.4 1 0 0 1 1 1 1 CS domain BTK PF00779.19 ORY96817.1 - 0.24 11.3 9.5 2.5 8.0 1.0 3.7 4 0 0 4 4 4 0 BTK motif DnaJ-X PF14308.6 ORY96818.1 - 4.4e-51 173.3 6.9 4.4e-51 173.3 6.9 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORY96818.1 - 3.3e-19 68.8 5.2 3.3e-19 68.8 5.2 2.2 2 0 0 2 2 2 1 DnaJ domain Neur PF00064.18 ORY96818.1 - 0.094 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Neuraminidase PepSY_2 PF13670.6 ORY96818.1 - 0.34 10.9 5.2 0.1 12.6 0.6 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF4047 PF13256.6 ORY96818.1 - 0.6 10.3 8.1 0.15 12.3 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Mito_carr PF00153.27 ORY96819.1 - 3.3e-67 222.5 0.4 1.8e-21 75.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY96819.1 - 0.00058 19.1 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 1 Gammaproteobacterial serine protease VPS9 PF02204.18 ORY96820.1 - 4.1e-15 55.9 0.0 1.1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain TFIIF_alpha PF05793.12 ORY96820.1 - 1.4 7.5 4.1 2.4 6.6 4.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ANAPC_CDC26 PF10471.9 ORY96820.1 - 3 8.8 12.6 13 6.7 12.6 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 TFIIE_alpha PF02002.17 ORY96821.1 - 1.4e-13 50.6 2.2 3.1e-13 49.5 2.2 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 ORY96821.1 - 0.00059 20.1 7.3 0.00059 20.1 7.3 2.9 1 1 1 2 2 2 1 C-terminal general transcription factor TFIIE alpha zf-RVT PF13966.6 ORY96821.1 - 0.04 14.6 0.5 0.15 12.8 0.3 2.0 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase TF_Zn_Ribbon PF08271.12 ORY96821.1 - 0.047 13.2 1.2 0.15 11.6 1.2 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding Imm41 PF15592.6 ORY96821.1 - 0.088 13.2 4.7 0.65 10.4 1.2 2.5 2 0 0 2 2 2 0 Immunity protein 41 RecR PF02132.15 ORY96821.1 - 0.15 11.6 1.2 0.39 10.3 0.1 2.2 2 0 0 2 2 2 0 RecR protein zinc-ribbons_6 PF07191.12 ORY96821.1 - 0.25 11.4 1.6 0.66 10.0 1.5 1.7 1 1 0 1 1 1 0 zinc-ribbons Rad50_zn_hook PF04423.14 ORY96821.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.4 3 0 0 3 3 3 0 Rad50 zinc hook motif BRO1 PF03097.18 ORY96822.1 - 1.3e-67 228.4 0.3 1.3e-67 228.4 0.3 2.0 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY96822.1 - 5.2e-61 206.5 9.5 9.9e-61 205.6 9.5 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV NifW PF03206.14 ORY96822.1 - 0.025 15.1 0.3 0.089 13.3 0.3 2.0 1 0 0 1 1 1 0 Nitrogen fixation protein NifW BRO1 PF03097.18 ORY96823.1 - 1.9e-21 76.3 0.0 2.2e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain Nrf1_DNA-bind PF10491.9 ORY96823.1 - 0.057 13.1 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 zf-C3HC4_3 PF13920.6 ORY96825.1 - 4.3e-07 29.7 9.1 4.3e-07 29.7 9.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 ORY96825.1 - 3.2e-05 22.7 8.8 3.2e-05 22.7 8.8 2.1 2 0 0 2 2 2 1 Macoilin family Prok-RING_4 PF14447.6 ORY96825.1 - 0.0096 15.8 9.3 0.024 14.5 9.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 GIT_CC PF16559.5 ORY96825.1 - 0.078 12.9 1.0 0.23 11.4 0.4 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor KxDL PF10241.9 ORY96825.1 - 0.12 12.7 6.5 0.34 11.2 6.5 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein V_ATPase_I PF01496.19 ORY96825.1 - 1.5 6.7 6.2 2 6.2 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn_Tnp_IS1 PF03811.13 ORY96825.1 - 1.5 8.6 6.0 0.22 11.3 0.5 2.6 2 0 0 2 2 2 0 InsA N-terminal domain FapA PF03961.13 ORY96825.1 - 5.4 5.5 7.1 7.7 5.0 7.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_1 PF00515.28 ORY96826.1 - 4.5e-16 57.9 17.4 7.5e-05 22.4 0.8 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY96826.1 - 1.1e-13 50.2 28.9 7.5e-05 22.6 0.4 9.6 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY96826.1 - 4.4e-11 43.1 20.4 0.00053 20.4 0.1 7.5 5 3 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY96826.1 - 2.2e-08 33.6 12.5 0.051 13.3 0.0 7.2 6 1 1 7 7 7 3 TPR repeat TPR_17 PF13431.6 ORY96826.1 - 3.6e-08 33.2 2.2 0.13 12.7 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY96826.1 - 4.5e-08 33.6 19.4 0.00046 20.8 0.1 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY96826.1 - 2.4e-06 27.3 16.7 0.23 11.8 0.1 8.1 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY96826.1 - 6.3e-06 26.3 12.8 0.66 10.2 0.4 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY96826.1 - 0.00014 22.3 20.0 0.28 12.1 0.1 8.1 7 1 2 9 9 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY96826.1 - 0.00018 21.8 16.1 0.098 13.0 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat ArnB_C PF18677.1 ORY96826.1 - 0.023 14.8 1.4 0.37 10.9 0.5 3.2 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain TPR_7 PF13176.6 ORY96826.1 - 0.11 12.5 13.0 1.6 8.9 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY96826.1 - 0.17 12.6 23.8 3.1 8.6 0.1 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF572 PF04502.13 ORY96826.1 - 7.7 6.0 9.9 23 4.4 9.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF572) Arf PF00025.21 ORY96827.1 - 6.4e-80 266.7 0.1 7.2e-80 266.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY96827.1 - 2.5e-14 53.5 0.0 3.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY96827.1 - 2.1e-13 50.2 1.2 1.7e-09 37.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY96827.1 - 2.7e-13 49.7 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY96827.1 - 5.7e-13 48.8 0.0 6.2e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY96827.1 - 2e-10 40.4 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY96827.1 - 6.6e-06 26.2 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY96827.1 - 0.0052 16.1 0.3 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Y_phosphatase PF00102.27 ORY96828.1 - 1.4e-62 211.3 0.0 2.1e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY96828.1 - 0.01 15.8 0.1 0.053 13.5 0.0 1.9 1 1 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 ORY96828.1 - 0.032 14.1 0.5 0.096 12.5 0.5 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 ORY96829.1 - 3.7e-52 177.3 0.0 8.4e-37 127.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96829.1 - 1.3e-20 73.8 0.0 2.6e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY96829.1 - 1.2e-10 41.2 0.0 2.8e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY96829.1 - 8.6e-06 25.2 0.2 1.3e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY96829.1 - 2.1e-05 24.5 0.2 3.8e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY96829.1 - 0.0011 18.0 0.1 0.011 14.7 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY96829.1 - 0.002 17.0 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 ORY96829.1 - 0.039 13.6 0.2 0.057 13.0 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MutS_V PF00488.21 ORY96830.1 - 5.5e-78 261.3 0.1 1.1e-77 260.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY96830.1 - 1.3e-38 133.2 0.5 5.7e-38 131.1 0.1 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 ORY96830.1 - 7.6e-33 113.1 0.5 1.5e-32 112.2 0.2 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 ORY96830.1 - 1.6e-12 47.9 0.0 4.3e-11 43.2 0.0 2.7 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ORY96830.1 - 8.8e-11 42.0 0.1 2.7e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 MutS family domain IV AAA_23 PF13476.6 ORY96830.1 - 0.072 13.6 0.3 0.38 11.2 0.3 2.2 1 0 0 1 1 1 0 AAA domain Ist1 PF03398.14 ORY96831.1 - 1.6e-64 216.7 3.9 1.9e-64 216.5 3.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RyR PF02026.16 ORY96831.1 - 0.1 12.8 0.1 2.3 8.5 0.0 2.6 2 1 1 3 3 3 0 RyR domain MMR_HSR1_Xtn PF16897.5 ORY96831.1 - 0.11 12.5 0.2 0.53 10.3 0.0 2.0 2 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ICMT PF04140.14 ORY96832.1 - 1.1e-23 83.4 1.5 2.2e-23 82.5 1.5 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORY96832.1 - 2.9e-12 46.9 1.9 6.5e-12 45.8 0.9 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 ORY96832.1 - 0.00011 21.8 2.8 0.00015 21.4 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 ORY96832.1 - 0.001 18.6 4.4 0.0015 18.1 4.4 1.3 1 0 0 1 1 1 1 NnrU protein DUF2428 PF10350.9 ORY96833.1 - 9.3e-70 235.0 0.0 2e-69 233.9 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) COG4 PF08318.12 ORY96833.1 - 0.084 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 COG4 transport protein E1_DerP2_DerF2 PF02221.15 ORY96834.1 - 6.9e-24 84.8 0.4 8.6e-24 84.5 0.4 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 ORY96834.1 - 5.4e-07 30.1 0.0 8.3e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 ML-like domain WD40 PF00400.32 ORY96835.1 - 1.2e-48 162.0 11.4 3.9e-08 33.8 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96835.1 - 6.4e-27 93.7 1.2 2.7e-05 24.4 0.1 6.5 3 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY96835.1 - 5.9e-07 29.5 0.7 0.18 11.6 0.0 4.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY96835.1 - 9.5e-05 21.9 0.0 0.0058 16.0 0.0 3.3 4 1 0 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 ORY96835.1 - 0.01 14.8 0.0 12 4.7 0.0 3.8 2 2 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY96835.1 - 0.011 14.4 3.3 0.19 10.3 0.0 3.2 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORY96835.1 - 0.041 13.2 0.1 4.1 6.7 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Vps16_N PF04841.13 ORY96835.1 - 0.046 12.5 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region GRAM PF02893.20 ORY96836.1 - 2.8e-23 82.0 0.0 5.3e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Methyltransf_34 PF11312.8 ORY96838.1 - 1.2e-53 182.4 1.1 2.7e-53 181.2 1.1 1.6 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase CheR PF01739.18 ORY96838.1 - 0.0028 17.2 0.2 0.12 11.8 0.1 2.5 2 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain Sds3 PF08598.11 ORY96839.1 - 4e-17 62.9 3.1 6.1e-17 62.4 3.1 1.3 1 0 0 1 1 1 1 Sds3-like NAM-associated PF14303.6 ORY96839.1 - 0.83 10.4 10.5 2 9.1 10.5 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Pkinase PF00069.25 ORY96840.1 - 4.1e-52 177.1 0.7 1e-51 175.8 0.7 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96840.1 - 1.1e-22 80.6 0.1 1.6e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY96840.1 - 0.0059 16.2 1.4 0.033 13.8 0.1 2.4 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 ORY96840.1 - 0.0075 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.29 ORY96841.1 - 1.2e-91 304.0 0.0 2.2e-44 151.1 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY96841.1 - 5e-25 87.0 8.1 4.1e-13 48.9 1.9 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORY96841.1 - 3.3e-15 56.2 0.0 2e-07 30.9 0.0 3.3 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY96841.1 - 7.8e-13 49.1 0.6 4.5e-07 30.4 0.0 3.6 3 1 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 ORY96841.1 - 4.1e-12 46.3 0.1 9.2e-06 25.7 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY96841.1 - 3.3e-11 43.6 0.0 2.1e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORY96841.1 - 2.9e-09 36.6 0.0 0.0021 17.4 0.0 2.4 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 ORY96841.1 - 4.3e-08 33.4 0.0 0.00027 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ORY96841.1 - 4.5e-08 33.4 0.6 0.026 14.8 0.1 4.2 2 2 1 3 3 3 2 AAA domain Rad17 PF03215.15 ORY96841.1 - 2.8e-06 27.4 0.0 0.012 15.6 0.0 2.8 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_14 PF13173.6 ORY96841.1 - 4.6e-06 26.7 0.0 0.0093 16.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORY96841.1 - 6.4e-06 26.5 0.0 0.19 12.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase CDC48_N PF02359.18 ORY96841.1 - 1e-05 25.6 0.0 4.3e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.17 ORY96841.1 - 1.3e-05 25.0 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY96841.1 - 1.9e-05 24.1 0.5 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORY96841.1 - 0.00033 20.2 0.0 0.42 10.1 0.0 3.1 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 ORY96841.1 - 0.00039 20.2 0.1 0.94 9.2 0.0 3.9 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 ORY96841.1 - 0.00039 20.7 0.0 0.46 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 ORY96841.1 - 0.00046 19.4 0.0 0.038 13.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY96841.1 - 0.00047 20.7 0.0 0.23 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ORY96841.1 - 0.00057 19.3 0.0 0.72 9.2 0.0 2.6 2 1 0 2 2 2 2 KaiC AAA_3 PF07726.11 ORY96841.1 - 0.0007 19.5 0.0 1.8 8.5 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 ORY96841.1 - 0.00091 19.2 0.0 0.58 10.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 ORY96841.1 - 0.0016 18.6 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 ORY96841.1 - 0.0025 17.6 0.0 0.5 10.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY96841.1 - 0.0035 16.6 0.0 0.67 9.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 ORY96841.1 - 0.0041 16.7 4.8 3.4 7.2 0.1 4.1 2 2 0 3 3 3 1 AAA domain IPT PF01745.16 ORY96841.1 - 0.01 15.2 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase NACHT PF05729.12 ORY96841.1 - 0.01 15.7 0.4 15 5.5 0.0 3.6 4 0 0 4 4 4 0 NACHT domain PhoH PF02562.16 ORY96841.1 - 0.018 14.5 0.1 0.84 9.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 ORY96841.1 - 0.033 14.0 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY96841.1 - 0.034 13.2 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 ORY96841.1 - 0.04 14.4 0.0 2.8 8.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 ORY96841.1 - 0.042 14.3 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY96841.1 - 0.047 14.0 0.4 0.67 10.3 0.0 2.6 2 2 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY96841.1 - 0.064 12.3 0.0 0.99 8.4 0.1 2.7 2 1 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.22 ORY96841.1 - 0.072 13.2 0.2 5.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase AAA_30 PF13604.6 ORY96841.1 - 0.1 12.3 0.1 2 8.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Ferritin PF00210.24 ORY96842.1 - 2e-38 131.5 3.0 2.3e-38 131.3 3.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ORY96842.1 - 1.8e-06 28.4 0.2 2.4e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 ORY96842.1 - 0.15 12.4 2.9 5.1 7.5 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) Amidohydro_1 PF01979.20 ORY96842.1 - 0.16 11.3 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase family O-FucT PF10250.9 ORY96843.1 - 7.1e-14 52.2 0.0 3.8e-09 36.7 0.0 2.5 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase DHHC PF01529.20 ORY96844.1 - 9.6e-38 129.3 10.9 9.6e-38 129.3 10.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF35_N PF12172.8 ORY96844.1 - 0.17 11.8 2.7 0.46 10.4 2.7 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TFIIA PF03153.13 ORY96845.1 - 0.0019 18.3 20.3 0.0019 18.2 20.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4228 PF14009.6 ORY96845.1 - 0.0027 18.1 1.4 0.0033 17.8 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) SRP-alpha_N PF04086.13 ORY96845.1 - 0.0033 17.4 7.5 0.0043 17.0 7.5 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CNDH2_C PF16858.5 ORY96845.1 - 0.0067 16.3 12.5 0.0084 16.0 12.5 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CAP PF00188.26 ORY96845.1 - 0.0096 16.8 0.5 0.014 16.3 0.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BUD22 PF09073.10 ORY96845.1 - 0.022 14.1 8.8 0.022 14.1 8.8 1.1 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 ORY96845.1 - 0.064 13.4 4.2 0.071 13.3 4.2 1.2 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 ORY96845.1 - 0.11 12.1 25.8 0.17 11.5 25.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF4746 PF15928.5 ORY96845.1 - 0.12 11.7 6.9 0.16 11.4 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TERB2 PF15101.6 ORY96845.1 - 0.13 12.2 9.0 0.16 12.0 9.0 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FoP_duplication PF13865.6 ORY96845.1 - 0.17 12.4 12.2 0.39 11.3 12.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cwf_Cwc_15 PF04889.12 ORY96845.1 - 0.29 10.8 15.0 0.39 10.4 15.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein V_ATPase_I PF01496.19 ORY96845.1 - 0.4 8.5 5.8 0.4 8.5 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folliculin PF11704.8 ORY96845.1 - 0.53 10.1 4.8 0.96 9.3 4.8 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Neur_chan_memb PF02932.16 ORY96845.1 - 0.54 10.3 4.5 0.62 10.1 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 ORY96845.1 - 0.66 8.7 7.3 0.69 8.7 7.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cut12 PF11500.8 ORY96845.1 - 0.7 9.8 14.7 1.2 9.1 14.6 1.4 1 1 0 1 1 1 0 Spindle pole body formation-associated protein CLN3 PF02487.17 ORY96845.1 - 0.99 8.4 5.4 1.2 8.1 5.4 1.2 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 ORY96845.1 - 1 8.0 11.8 1.2 7.8 11.8 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 ORY96845.1 - 1.1 8.6 3.3 1.4 8.2 3.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2722 PF10846.8 ORY96845.1 - 1.8 7.4 20.0 2.4 7.0 20.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Hid1 PF12722.7 ORY96845.1 - 3.4 5.7 11.0 4.1 5.4 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SURF2 PF05477.11 ORY96845.1 - 3.8 7.1 13.6 4.9 6.8 13.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Kei1 PF08552.11 ORY96845.1 - 4.2 7.2 5.3 5.9 6.7 5.3 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Aminotran_1_2 PF00155.21 ORY96846.1 - 3.7e-37 128.4 0.0 4.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II FLILHELTA PF10306.9 ORY96847.1 - 3.1e-12 46.7 0.0 5.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 ORY96847.1 - 0.00058 20.4 0.1 0.0014 19.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) zf-C2H2 PF00096.26 ORY96848.1 - 2.7e-12 46.4 9.6 4.1e-06 27.0 4.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY96848.1 - 1.9e-09 37.5 14.8 1.8e-07 31.3 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY96848.1 - 2.8e-08 33.9 8.7 0.0013 19.3 3.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY96848.1 - 1.6e-05 24.8 2.6 1.6e-05 24.8 2.6 2.2 2 1 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 ORY96848.1 - 0.00022 21.5 1.7 0.00022 21.5 1.7 1.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY96848.1 - 0.0019 17.9 5.7 0.16 11.7 0.2 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 ORY96848.1 - 0.017 15.3 0.4 0.031 14.4 0.1 1.5 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORY96848.1 - 0.017 15.4 1.6 0.93 9.8 0.0 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 ORY96848.1 - 0.047 13.6 6.9 1.4 9.0 2.0 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 ORY96848.1 - 0.08 13.3 4.9 0.094 13.0 1.1 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY96848.1 - 0.19 12.1 2.4 0.42 11.0 1.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.22 ORY96849.1 - 6.8e-29 99.5 0.2 8.6e-20 70.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 ORY96849.1 - 6.5e-17 62.4 0.7 1.7e-16 61.1 0.7 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 ORY96849.1 - 2.2e-05 24.4 0.5 0.014 15.5 0.0 3.2 2 1 1 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 ORY96849.1 - 0.0012 18.7 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY96849.1 - 0.0028 17.2 0.0 0.07 12.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 ORY96849.1 - 0.087 12.7 0.7 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 RNA recognition motif RRM_7 PF16367.5 ORY96849.1 - 0.11 12.6 0.0 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif MFS_1 PF07690.16 ORY96851.1 - 1.8e-46 158.7 50.0 1.3e-38 132.8 29.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4577 PF15145.6 ORY96851.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Gly-zipper_OmpA PF13436.6 ORY96851.1 - 0.58 10.0 4.6 1.1 9.1 4.6 1.3 1 0 0 1 1 1 0 Glycine-zipper domain Amidohydro_3 PF07969.11 ORY96852.1 - 6.5e-13 48.9 0.3 1e-05 25.3 0.2 2.9 1 1 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 ORY96852.1 - 8.3e-10 38.5 0.0 9.1e-09 35.1 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY96852.1 - 0.0014 19.0 0.2 0.0024 18.2 0.2 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Ribonuc_L-PSP PF01042.21 ORY96853.1 - 8.4e-39 132.3 0.0 1e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP D-ser_dehydrat PF14031.6 ORY96854.1 - 5.1e-20 71.9 0.0 1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 ORY96854.1 - 3.6e-18 66.0 0.7 4.5e-18 65.7 0.7 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MFS_1 PF07690.16 ORY96855.1 - 2e-48 165.1 42.8 4e-48 164.1 42.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY96855.1 - 9.8e-18 64.2 8.8 9.8e-18 64.2 8.8 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 ORY96855.1 - 6.9e-17 61.1 23.7 9.7e-17 60.6 23.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TssO PF17561.2 ORY96855.1 - 0.07 13.2 0.6 22 5.2 0.0 3.5 3 0 0 3 3 3 0 Type VI secretion system, TssO HSP70 PF00012.20 ORY96856.1 - 0.00025 19.4 0.0 0.00054 18.3 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein W2 PF02020.18 ORY96856.1 - 0.16 12.1 0.1 0.46 10.7 0.1 1.7 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon DPBB_1 PF03330.18 ORY96857.1 - 7.8e-11 42.1 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY96857.1 - 0.0018 18.1 0.1 0.0027 17.5 0.1 1.3 1 1 0 1 1 1 1 Barwin family HlyIII PF03006.20 ORY96858.1 - 4.6e-60 203.1 26.3 5.8e-60 202.8 26.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Apo-CII PF05355.11 ORY96858.1 - 0.18 12.0 0.2 0.63 10.2 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein C-II MHYT PF03707.16 ORY96859.1 - 1.3e-27 95.7 16.2 1.5e-09 37.9 0.8 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Smoa_sbd PF17885.1 ORY96859.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Styrene monooxygenase A putative substrate binding domain DUF805 PF05656.14 ORY96859.1 - 3 8.3 7.6 17 5.8 7.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Saf_2TM PF18303.1 ORY96859.1 - 5.9 6.5 5.5 2.8 7.5 0.2 2.8 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain Arm PF00514.23 ORY96860.1 - 1.1e-09 37.9 4.3 3.1 8.0 0.0 7.3 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY96860.1 - 4e-06 27.1 0.7 0.28 11.6 0.0 4.5 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.22 ORY96860.1 - 0.0011 19.1 0.2 7.5 7.1 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat DUF383 PF04063.14 ORY96860.1 - 0.0038 16.9 0.5 1.4 8.6 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF383) Atx10homo_assoc PF09759.9 ORY96860.1 - 0.0042 17.1 4.5 0.23 11.5 0.1 4.3 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 ORY96860.1 - 0.011 15.8 0.2 0.21 11.7 0.2 2.8 2 0 0 2 2 2 0 V-ATPase subunit H HEAT_EZ PF13513.6 ORY96860.1 - 0.026 15.0 0.6 26 5.5 0.1 4.2 3 1 1 4 4 4 0 HEAT-like repeat DUF3636 PF12331.8 ORY96860.1 - 0.05 13.5 0.1 2.4 8.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3636) HXXSHH PF07586.11 ORY96860.1 - 0.079 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) UNC45-central PF11701.8 ORY96860.1 - 0.18 11.8 3.1 0.37 10.7 0.7 2.7 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF5547 PF17701.1 ORY96862.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5547) VRR_NUC PF08774.11 ORY96863.1 - 9.8e-27 93.2 0.0 2.9e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Rota_NS6 PF04866.12 ORY96863.1 - 0.084 13.1 0.4 0.47 10.7 0.1 2.3 2 0 0 2 2 2 0 Rotavirus non-structural protein 6 Bestrophin PF01062.21 ORY96864.1 - 2.8e-42 145.1 0.0 1.1e-41 143.2 0.0 1.7 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.18 ORY96865.1 - 1.7e-13 50.4 28.6 4.4e-09 36.3 10.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC32 PF14989.6 ORY96865.1 - 0.0016 18.4 1.5 0.0037 17.3 0.8 1.8 2 0 0 2 2 2 1 Coiled-coil domain containing 32 HrpB7 PF09486.10 ORY96865.1 - 1.6 9.1 9.5 1.3 9.3 7.9 1.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Dickkopf_N PF04706.12 ORY96865.1 - 9.3 6.8 20.7 15 6.2 6.0 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region LRR_4 PF12799.7 ORY96866.1 - 0.0025 18.2 1.0 0.79 10.2 0.0 3.5 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY96866.1 - 0.0051 16.8 8.7 3 8.1 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.7 ORY96866.1 - 0.47 10.4 0.0 0.47 10.4 0.0 2.7 4 0 0 4 4 4 0 F-box-like Y_phosphatase3 PF13350.6 ORY96867.1 - 9.4e-44 150.1 0.0 1.1e-43 149.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY96867.1 - 2.4e-05 24.0 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 ORY96867.1 - 0.0089 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY96867.1 - 0.01 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY96867.1 - 0.043 13.9 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Hydrolase_4 PF12146.8 ORY96868.1 - 1.4e-10 40.8 0.0 1.6e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY96868.1 - 6.9e-07 29.2 0.0 0.00039 20.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY96868.1 - 2.4e-06 28.3 0.0 4.2e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORY96868.1 - 2.3e-05 24.3 0.0 0.04 13.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY96868.1 - 0.0007 19.1 0.2 0.0025 17.3 0.2 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 ORY96868.1 - 0.0051 15.9 0.0 0.016 14.3 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1749) BAAT_C PF08840.11 ORY96868.1 - 0.0064 16.4 0.0 0.0086 16.0 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal WD40 PF00400.32 ORY96869.1 - 3.4e-09 37.2 7.0 0.0019 19.0 0.1 4.6 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96869.1 - 9.8e-05 22.6 0.0 0.0043 17.3 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 ORY96869.1 - 0.021 14.8 0.4 0.93 9.5 0.1 3.7 5 0 0 5 5 5 0 WD domain, G-beta repeat eIF2A PF08662.11 ORY96869.1 - 0.039 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ORY96870.1 - 1.1e-23 83.0 10.0 3.1e-05 24.7 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 ORY96870.1 - 2.3e-08 33.1 1.0 0.11 11.1 0.0 3.1 2 1 0 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 ORY96870.1 - 0.00033 20.3 0.5 0.00043 20.0 0.5 1.2 1 0 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 ORY96870.1 - 0.00043 20.5 0.0 12 6.2 0.0 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY96870.1 - 0.0059 16.0 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain Mannosidase_ig PF17786.1 ORY96870.1 - 0.072 13.7 0.1 0.15 12.7 0.1 1.8 1 1 0 1 1 1 0 Mannosidase Ig/CBM-like domain Amidohydro_1 PF01979.20 ORY96872.1 - 3.2e-70 237.2 0.5 4.2e-70 236.8 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY96872.1 - 5.2e-55 185.0 1.2 1.4e-54 183.6 1.2 1.8 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ORY96872.1 - 8.1e-42 141.2 0.1 1.3e-41 140.5 0.1 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 ORY96872.1 - 5.7e-18 65.1 0.1 1.5e-17 63.7 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ORY96872.1 - 1.9e-08 34.2 0.1 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PapD_N PF00345.20 ORY96872.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Aa_trans PF01490.18 ORY96873.1 - 6.3e-57 193.1 26.4 7.3e-57 192.9 26.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phi_1 PF04674.12 ORY96876.1 - 3.9e-30 105.1 2.0 5.4e-30 104.6 2.0 1.2 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region HORMA PF02301.18 ORY96877.1 - 9.4e-17 61.3 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 HORMA domain DUF3168 PF11367.8 ORY96877.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) bacHORMA_2 PF18173.1 ORY96877.1 - 0.018 14.9 0.5 0.046 13.6 0.4 1.7 1 1 0 1 1 1 0 Bacterial HORMA domain 2 DUF3712 PF12505.8 ORY96878.1 - 4.1e-53 178.9 44.2 1.6e-18 67.2 0.6 9.0 8 3 2 10 10 10 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORY96878.1 - 1.9e-10 41.1 8.2 1.3 9.6 0.0 7.9 8 0 0 8 8 8 5 Late embryogenesis abundant protein ODV-E18 PF10717.9 ORY96878.1 - 0.0045 16.8 1.2 0.029 14.2 1.2 2.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Synaptobrevin PF00957.21 ORY96879.1 - 1.1e-32 111.6 1.5 1.3e-32 111.4 1.5 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF5345 PF17280.2 ORY96879.1 - 0.013 15.4 0.1 0.028 14.4 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) MMPL PF03176.15 ORY96879.1 - 0.018 14.0 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 MMPL family ETRAMP PF09716.10 ORY96879.1 - 0.039 14.0 1.0 0.048 13.7 0.8 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MCU PF04678.13 ORY96879.1 - 0.063 13.4 0.1 0.071 13.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ferlin_C PF16165.5 ORY96879.1 - 0.1 12.5 4.0 0.14 12.1 3.6 1.4 1 1 0 1 1 1 0 Ferlin C-terminus Fzo_mitofusin PF04799.13 ORY96879.1 - 0.85 9.2 5.5 0.26 10.8 0.5 2.0 1 1 1 2 2 2 0 fzo-like conserved region SCIMP PF15050.6 ORY96879.1 - 0.9 10.0 3.6 1.7 9.1 3.6 1.4 1 0 0 1 1 1 0 SCIMP protein PAS_6 PF08348.11 ORY96880.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 YheO-like PAS domain DUF2985 PF11204.8 ORY96880.1 - 0.039 14.1 1.4 0.095 12.9 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2985) CTD_bind PF04818.13 ORY96881.1 - 1e-05 26.3 0.0 3.8e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 ORY96881.1 - 0.01 16.3 5.4 0.024 15.1 0.2 2.7 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 zinc_ribbon_9 PF14369.6 ORY96881.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon DNA_RNApol_7kD PF03604.13 ORY96881.1 - 0.25 11.0 0.5 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Suf PF05843.14 ORY96881.1 - 6.4 6.7 13.1 17 5.3 13.1 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RNF220 PF15926.5 ORY96882.1 - 1.7e-29 103.2 7.9 3.2e-29 102.3 7.9 1.5 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 ORY96882.1 - 6e-11 42.0 18.5 9e-11 41.4 10.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY96882.1 - 0.00011 22.0 14.1 0.069 13.0 7.4 3.3 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY96882.1 - 0.00023 21.1 8.4 0.00023 21.1 8.4 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY96882.1 - 0.00063 20.0 21.1 0.0015 18.8 11.5 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 ORY96882.1 - 0.00077 19.3 10.3 0.00077 19.3 10.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY96882.1 - 0.00099 18.9 17.8 0.0053 16.6 7.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY96882.1 - 0.023 14.8 2.0 0.023 14.8 2.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY96882.1 - 0.029 14.4 9.9 0.029 14.4 9.9 3.7 4 0 0 4 4 4 0 RING-type zinc-finger DZR PF12773.7 ORY96882.1 - 1.8 8.6 9.6 31 4.7 4.6 3.4 3 1 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 ORY96882.1 - 4.5 6.8 6.6 24 4.5 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbon domain WD40 PF00400.32 ORY96883.1 - 3.1e-12 46.8 14.3 2.3e-06 28.2 0.1 6.8 7 0 0 7 7 7 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ORY96883.1 - 4.9e-09 35.7 12.1 1.5e-08 34.1 12.1 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 ORY96883.1 - 5.1e-05 23.5 0.6 1.7 9.0 0.0 4.6 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Rep_fac-A_C PF08646.10 ORY96883.1 - 0.0054 16.5 3.2 0.013 15.3 3.2 1.6 1 0 0 1 1 1 1 Replication factor-A C terminal domain zinc_ribbon_16 PF17034.5 ORY96883.1 - 0.085 13.1 14.9 0.032 14.5 4.9 2.5 1 1 1 2 2 2 0 Zinc-ribbon like family MFS_1 PF07690.16 ORY96884.1 - 3.6e-32 111.7 28.8 4.6e-32 111.3 28.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RabGAP-TBC PF00566.18 ORY96886.1 - 3.2e-25 89.1 3.9 4.4e-16 59.2 0.1 2.3 1 1 1 2 2 2 2 Rab-GTPase-TBC domain TnpV PF14198.6 ORY96886.1 - 0.057 13.4 0.3 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Transposon-encoded protein TnpV FYVE PF01363.21 ORY96888.1 - 1.1e-19 70.3 7.3 1.1e-19 70.3 7.3 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 ORY96888.1 - 3.7e-08 33.6 3.9 3.7e-08 33.6 3.9 3.7 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY96888.1 - 1.4e-05 24.8 3.8 1.4e-05 24.8 3.8 4.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 ORY96888.1 - 0.001 19.3 1.5 0.001 19.3 1.5 2.5 4 0 0 4 4 4 1 FYVE-type zinc finger FANCL_C PF11793.8 ORY96888.1 - 0.0015 18.7 3.3 0.0015 18.7 3.3 2.9 3 0 0 3 3 3 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 ORY96888.1 - 0.0015 18.5 4.7 0.0015 18.5 4.7 3.7 4 0 0 4 4 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY96888.1 - 0.017 15.4 5.3 0.017 15.4 5.3 3.0 3 1 0 3 3 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY96888.1 - 0.029 14.2 2.6 0.029 14.2 2.6 4.2 4 1 0 4 4 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY96888.1 - 0.068 12.9 8.4 0.055 13.2 5.8 2.3 2 0 0 2 2 2 0 RING-like zinc finger Rad50_zn_hook PF04423.14 ORY96888.1 - 0.095 12.6 1.4 0.5 10.2 0.3 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Mss51 PF13824.6 ORY96888.1 - 0.3 11.2 0.2 0.3 11.2 0.2 4.6 4 1 0 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2HC5 PF06221.13 ORY96888.1 - 0.43 10.6 11.1 3.6 7.6 0.1 3.6 3 1 0 3 3 3 0 Putative zinc finger motif, C2HC5-type TFIIA PF03153.13 ORY96889.1 - 7.2 6.5 13.2 7 6.5 13.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_1 PF00583.25 ORY96890.1 - 1.2e-12 48.1 0.1 1.5e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY96890.1 - 8.6e-08 32.5 0.1 1.1e-07 32.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY96890.1 - 3.4e-07 30.2 0.0 4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY96890.1 - 1e-06 28.6 0.1 1.3e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ORY96890.1 - 3.5e-05 24.0 0.0 4.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 ORY96890.1 - 0.0081 16.1 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Nudix hydrolase domain Acetyltransf_15 PF17013.5 ORY96890.1 - 0.032 13.7 0.5 0.038 13.5 0.5 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_8 PF13523.6 ORY96890.1 - 0.035 13.8 0.0 0.073 12.7 0.0 1.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY96890.1 - 0.11 12.6 0.2 0.13 12.3 0.2 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glu-tRNAGln PF02686.15 ORY96891.1 - 5.7e-09 36.1 0.0 8.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Na_Ca_ex PF01699.24 ORY96892.1 - 1.9e-38 131.8 38.1 2.9e-19 69.5 14.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DPM3 PF08285.11 ORY96892.1 - 0.096 12.9 0.0 0.096 12.9 0.0 3.8 3 1 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pho88 PF10032.9 ORY96893.1 - 3.5e-55 186.1 0.0 3.9e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) SNRNP27 PF08648.12 ORY96893.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Mso1_Sec1_bdg PF14475.6 ORY96894.1 - 8.5e-09 34.9 0.3 8.5e-09 34.9 0.3 2.2 2 0 0 2 2 2 1 Sec1-binding region of Mso1 Metallophos PF00149.28 ORY96895.1 - 2.7e-09 37.8 2.0 3.7e-09 37.4 0.6 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase HTH_ABP1_N PF18107.1 ORY96896.1 - 1.2e-08 34.6 1.0 1.6e-08 34.1 1.0 1.1 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_33 PF13592.6 ORY96896.1 - 3.9e-06 26.4 0.1 6.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 ORY96896.1 - 0.0014 19.2 0.1 0.0018 18.9 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Arg_repressor PF01316.21 ORY96896.1 - 0.0046 16.7 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DUF5427 PF10310.9 ORY96897.1 - 5.1e-50 170.8 8.3 1.1e-43 149.9 0.0 3.3 1 1 2 3 3 3 3 Family of unknown function (DUF5427) AMP-binding PF00501.28 ORY96898.1 - 1.4e-95 320.4 0.0 1.8e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY96898.1 - 1.2e-22 80.6 0.5 3e-22 79.4 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORY96898.1 - 1.8e-19 69.4 2.2 6.9e-19 67.5 0.6 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus CI-B14_5a PF07347.12 ORY96899.1 - 0.0008 19.2 1.1 0.0014 18.5 0.6 1.7 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) LRR_4 PF12799.7 ORY96900.1 - 1.7e-25 88.6 25.0 4e-06 27.1 0.8 5.7 4 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY96900.1 - 5.1e-19 68.4 21.2 2.4e-13 50.0 0.1 3.9 2 1 3 5 5 5 3 Leucine-rich repeat LRR_8 PF13855.6 ORY96900.1 - 8.2e-16 57.5 32.2 8.4e-06 25.5 1.7 5.5 2 1 5 7 7 7 6 Leucine rich repeat LRR_6 PF13516.6 ORY96900.1 - 2.8e-05 23.8 26.6 0.51 10.5 0.2 8.0 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 ORY96900.1 - 0.00015 21.8 16.5 0.95 10.3 0.1 7.5 7 1 0 7 7 7 1 Leucine Rich Repeat Borrelia_P83 PF05262.11 ORY96900.1 - 0.11 11.0 15.1 0.14 10.6 15.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LRR_5 PF13306.6 ORY96900.1 - 0.29 11.1 5.6 0.28 11.2 0.7 2.5 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Pkinase PF00069.25 ORY96902.1 - 4.5e-54 183.6 0.1 1.2e-53 182.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96902.1 - 9.4e-20 71.0 0.0 1.9e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY96902.1 - 0.0077 16.2 0.0 0.0077 16.2 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY96902.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.3 3 0 0 3 3 3 0 RIO1 family Choline_kinase PF01633.20 ORY96902.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.1 2 1 0 2 2 2 0 Choline/ethanolamine kinase DUF1676 PF07898.13 ORY96902.1 - 4.9 7.2 9.1 17 5.4 1.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Med6 PF04934.14 ORY96903.1 - 1.2e-37 128.7 0.3 1.3e-37 128.5 0.3 1.0 1 0 0 1 1 1 1 MED6 mediator sub complex component Homeodomain PF00046.29 ORY96903.1 - 0.071 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Homeodomain FYVE PF01363.21 ORY96905.1 - 2.1e-18 66.2 12.3 2.9e-16 59.3 9.8 2.9 2 0 0 2 2 2 2 FYVE zinc finger Pep1_7 PF17232.2 ORY96905.1 - 0.12 12.8 6.8 11 6.6 1.0 3.7 3 0 0 3 3 3 0 Elicitor peptide 1-7 zf-AN1 PF01428.16 ORY96905.1 - 0.47 10.7 11.6 1.4 9.1 11.6 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger TEA PF01285.18 ORY96906.1 - 3.4e-31 107.1 0.0 7.7e-31 106.0 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain YBD PF17725.1 ORY96906.1 - 3.4e-06 27.1 0.6 6e-06 26.3 0.6 1.5 1 0 0 1 1 1 1 YAP binding domain Pheromone PF08015.11 ORY96906.1 - 7.5 7.7 10.4 1.5 9.9 0.2 3.1 3 0 0 3 3 3 0 Fungal mating-type pheromone CLASP_N PF12348.8 ORY96907.1 - 1.8e-59 201.1 0.4 3.1e-59 200.3 0.4 1.4 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 ORY96907.1 - 0.00012 22.1 0.0 0.72 10.3 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat DUF4611 PF15387.6 ORY96907.1 - 0.16 12.2 2.2 0.78 10.0 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) IDO PF01231.18 ORY96908.1 - 1.2e-140 469.2 0.0 3e-140 467.9 0.0 1.6 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 ORY96908.1 - 0.051 12.3 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Cyclin_N PF00134.23 ORY96909.1 - 1.7e-17 63.4 0.4 1.7e-15 56.9 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY96909.1 - 1.2e-05 25.4 0.7 0.00071 19.7 0.3 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 ORY96909.1 - 0.00032 20.7 0.1 0.67 10.1 0.0 2.6 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Gtr1_RagA PF04670.12 ORY96910.1 - 9.3e-72 241.1 2.4 1.2e-71 240.8 2.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 ORY96910.1 - 2.5e-07 30.3 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY96910.1 - 3.2e-05 23.4 0.0 5.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY96910.1 - 3.9e-05 23.7 0.0 0.00029 20.9 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 ORY96910.1 - 5.4e-05 22.9 0.3 8.5e-05 22.2 0.3 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY96910.1 - 7.8e-05 22.9 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ORY96910.1 - 0.00051 19.9 0.4 0.00084 19.2 0.4 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MerC PF03203.14 ORY96911.1 - 0.0091 16.4 3.3 0.0091 16.4 3.3 1.9 1 1 1 2 2 2 1 MerC mercury resistance protein CitMHS PF03600.16 ORY96911.1 - 0.011 14.9 4.3 0.014 14.6 4.3 1.1 1 0 0 1 1 1 0 Citrate transporter DUF373 PF04123.13 ORY96911.1 - 0.32 10.4 2.9 0.38 10.2 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pkinase PF00069.25 ORY96912.1 - 1.4e-65 221.3 0.0 1.8e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96912.1 - 1.7e-29 102.9 0.0 3.1e-29 102.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY96912.1 - 0.00013 21.4 0.1 0.0003 20.2 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Imm7 PF15585.6 ORY96912.1 - 0.016 15.5 0.0 0.057 13.7 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 7 DegV PF02645.16 ORY96912.1 - 0.086 12.2 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 APH PF01636.23 ORY96912.1 - 0.096 12.6 0.2 0.33 10.8 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 ORY96913.1 - 1.7e-07 30.8 0.0 1.4e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY96913.1 - 0.065 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CBF PF03914.17 ORY96914.1 - 6.8e-32 110.8 0.3 6.8e-32 110.8 0.3 3.3 3 1 0 3 3 3 1 CBF/Mak21 family Methyltransf_5 PF01795.19 ORY96915.1 - 5.7e-57 193.6 0.1 7e-56 190.0 0.1 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 ORY96915.1 - 0.0033 18.1 0.0 0.0065 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY96915.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY96915.1 - 0.15 12.7 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORY96915.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PSP1 PF04468.12 ORY96916.1 - 3.5e-32 110.5 5.6 3.5e-32 110.5 5.6 1.8 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Pex14_N PF04695.13 ORY96916.1 - 0.012 16.3 8.5 0.015 15.9 8.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR1 PF08505.10 ORY96916.1 - 0.02 15.2 4.2 0.022 15.1 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein MAM33 PF02330.16 ORY96916.1 - 0.064 13.2 3.2 0.085 12.8 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial glycoprotein TFIIA PF03153.13 ORY96916.1 - 0.17 11.9 15.9 0.2 11.6 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPATA3 PF15662.5 ORY96916.1 - 0.3 11.7 8.0 0.37 11.4 8.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Roughex PF06020.11 ORY96916.1 - 1.1 8.3 8.5 1.4 8.0 8.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 ORY96916.1 - 2.3 6.9 4.4 2.8 6.6 4.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 ORY96916.1 - 2.7 5.8 18.1 3.2 5.5 18.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) IreB PF06135.12 ORY96918.1 - 0.13 12.5 0.2 0.34 11.1 0.1 1.8 2 0 0 2 2 2 0 IreB regulatory phosphoprotein ProSAAS PF07259.12 ORY96918.1 - 0.64 10.0 2.8 13 5.7 0.1 2.0 1 1 1 2 2 2 0 ProSAAS precursor Pkinase PF00069.25 ORY96919.1 - 1.1e-74 251.2 0.0 1.6e-74 250.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96919.1 - 8.2e-30 103.9 0.0 5.5e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY96919.1 - 1.5e-07 31.1 0.1 0.4 10.0 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 ORY96919.1 - 0.013 14.3 0.1 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 ORY96919.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY96919.1 - 0.044 13.7 0.0 3.4 7.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Xan_ur_permease PF00860.20 ORY96920.1 - 4.2e-56 190.3 32.1 9.7e-55 185.8 32.1 2.0 1 1 0 1 1 1 1 Permease family DUF4134 PF13572.6 ORY96920.1 - 2.3 8.6 6.1 0.31 11.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) MFS_1_like PF12832.7 ORY96921.1 - 5.3e-18 65.0 25.4 3.1e-17 62.5 25.4 2.0 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 ORY96921.1 - 0.0019 17.2 43.4 0.025 13.5 11.9 3.4 2 2 1 3 3 3 3 Major Facilitator Superfamily SRP9-21 PF05486.12 ORY96921.1 - 0.051 14.0 0.4 0.096 13.1 0.4 1.4 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) SUIM_assoc PF16619.5 ORY96921.1 - 0.066 13.3 5.4 0.13 12.3 5.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF5383 PF17355.2 ORY96921.1 - 0.21 12.0 0.9 0.44 10.9 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Abhydrolase_3 PF07859.13 ORY96922.1 - 6.2e-63 212.5 0.0 8.1e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY96922.1 - 6.3e-06 25.3 0.0 9.2e-05 21.5 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORY96922.1 - 1.4e-05 24.7 0.0 3.2e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ORY96922.1 - 0.00087 18.3 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 ORY96922.1 - 0.02 15.5 0.6 0.13 12.8 0.6 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 ORY96922.1 - 0.061 12.9 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.12 ORY96922.1 - 0.071 11.8 0.0 0.21 10.2 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PCP_red PF08369.10 ORY96922.1 - 0.076 13.2 0.2 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit SUKH-3 PF14433.6 ORY96922.1 - 0.098 13.1 0.0 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 SUKH-3 immunity protein eIF_4EBP PF05456.11 ORY96923.1 - 4.4e-27 94.3 0.5 4.9e-27 94.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) HRDC PF00570.23 ORY96923.1 - 0.13 12.3 0.1 0.44 10.6 0.1 1.9 2 0 0 2 2 2 0 HRDC domain CRIM PF16978.5 ORY96926.1 - 1.3e-42 145.3 0.0 5.2e-42 143.3 0.0 2.1 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 ORY96926.1 - 7.3e-29 100.2 0.9 1.9e-28 98.9 0.9 1.8 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 ORY96926.1 - 0.055 13.5 0.0 0.96 9.6 0.0 2.5 2 0 0 2 2 2 0 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 ORY96926.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain PH PF00169.29 ORY96926.1 - 0.065 13.8 0.1 0.18 12.3 0.1 1.8 1 0 0 1 1 1 0 PH domain Pkinase PF00069.25 ORY96927.1 - 2.4e-36 125.5 0.0 2e-12 47.0 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96927.1 - 7e-18 64.8 0.0 6.5e-10 38.7 0.0 4.0 3 1 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 ORY96927.1 - 0.055 12.8 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Yuri_gagarin PF15934.5 ORY96927.1 - 0.098 12.5 3.0 0.18 11.6 0.6 2.1 2 0 0 2 2 2 0 Yuri gagarin betaPIX_CC PF16523.5 ORY96927.1 - 0.16 11.8 0.6 0.34 10.8 0.6 1.4 1 0 0 1 1 1 0 betaPIX coiled coil SlyX PF04102.12 ORY96927.1 - 0.35 11.5 5.2 0.85 10.3 5.2 1.6 1 0 0 1 1 1 0 SlyX YabA PF06156.13 ORY96927.1 - 0.4 11.4 3.3 1 10.1 3.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Vps8 PF12816.7 ORY96928.1 - 1.1e-68 230.7 0.0 8.7e-66 221.2 0.0 2.9 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 ORY96928.1 - 1.6e-10 41.0 0.2 3.5e-05 23.7 0.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 ORY96928.1 - 0.0003 20.7 3.2 0.00079 19.3 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY96928.1 - 0.0018 18.5 1.7 0.0048 17.2 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY96928.1 - 0.004 17.0 4.1 0.004 17.0 4.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY96928.1 - 0.0052 16.6 1.7 0.015 15.2 1.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 WD40 PF00400.32 ORY96928.1 - 0.015 16.1 0.3 0.074 14.0 0.3 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 ORY96928.1 - 0.024 14.5 1.9 0.058 13.3 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 ORY96928.1 - 0.03 14.4 4.6 0.09 12.8 4.6 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 ORY96928.1 - 0.04 13.7 1.0 0.11 12.3 1.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 ORY96928.1 - 0.06 13.7 8.1 0.012 15.9 4.1 1.9 2 0 0 2 2 1 0 Ring finger domain zf-RING_UBOX PF13445.6 ORY96928.1 - 0.53 10.3 7.5 0.033 14.2 1.8 1.9 2 0 0 2 2 1 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 ORY96928.1 - 3.9 7.7 5.5 3.8 7.7 3.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4 PF00097.25 ORY96928.1 - 7.5 6.5 6.6 1.3 9.0 2.6 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) DUF962 PF06127.11 ORY96929.1 - 6.2e-33 112.8 0.3 7.3e-33 112.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Med22 PF06179.12 ORY96930.1 - 4e-20 72.0 5.3 4.8e-20 71.7 5.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Med4 PF10018.9 ORY96930.1 - 0.0092 15.7 2.8 0.013 15.1 2.8 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ABC_membrane PF00664.23 ORY96931.1 - 5.7e-45 154.1 0.8 8.3e-45 153.6 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY96931.1 - 6.6e-38 130.3 0.0 1.3e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY96931.1 - 6.3e-06 25.8 3.6 0.00027 20.5 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY96931.1 - 0.00049 19.8 0.3 0.0015 18.2 0.3 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORY96931.1 - 0.00073 18.9 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 ORY96931.1 - 0.002 18.6 0.1 0.0063 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY96931.1 - 0.0058 16.9 0.3 0.17 12.1 0.6 2.5 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ORY96931.1 - 0.019 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 ORY96931.1 - 0.066 13.6 0.2 0.87 10.0 0.1 2.5 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY96931.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 ORY96931.1 - 0.086 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 ORY96931.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 ORY96931.1 - 0.11 12.2 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FAST_2 PF08368.12 ORY96931.1 - 0.14 13.0 0.0 0.29 11.9 0.0 1.5 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 DEAD PF00270.29 ORY96931.1 - 0.15 11.8 0.4 2 8.2 0.4 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 ORY96931.1 - 0.18 12.3 0.2 0.42 11.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain STE2 PF02116.15 ORY96932.1 - 0.038 13.3 0.2 0.05 12.9 0.2 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DNA_methylase PF00145.17 ORY96934.1 - 5.5e-30 104.8 0.0 9.3e-29 100.8 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Pro_isomerase PF00160.21 ORY96935.1 - 6.6e-48 163.0 0.1 7.5e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ORY96936.1 - 3.2e-18 65.8 5.3 1.1e-06 29.2 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96936.1 - 3.7e-09 36.7 0.1 0.0036 17.6 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 ORY96936.1 - 0.0079 15.8 0.1 0.17 11.4 0.0 2.3 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region WD40_like PF17005.5 ORY96936.1 - 0.023 14.0 0.0 0.45 9.8 0.0 2.1 1 1 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 ORY96936.1 - 0.042 13.7 0.1 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TRAPPC10 PF12584.8 ORY96937.1 - 1.4e-19 70.3 0.0 2.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 ORY96937.1 - 0.018 15.0 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking BORCS6 PF10157.9 ORY96937.1 - 0.083 13.1 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Pkinase PF00069.25 ORY96938.1 - 4.1e-72 242.7 0.0 5.7e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY96938.1 - 1.4e-37 129.4 0.0 2.7e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY96938.1 - 5.1e-05 23.3 0.0 0.00078 19.4 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY96938.1 - 0.0012 17.9 0.1 0.0012 17.9 0.1 2.0 3 0 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 ORY96938.1 - 0.003 16.9 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 ORY96938.1 - 0.031 13.9 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 ORY96938.1 - 0.045 13.4 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Zn_clus PF00172.18 ORY96939.1 - 1.7e-09 37.7 8.1 3.1e-09 36.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tme5_EGF_like PF09064.10 ORY96939.1 - 0.65 9.9 5.5 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like WD40 PF00400.32 ORY96940.1 - 2.9e-30 103.8 5.9 1e-07 32.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY96940.1 - 9.3e-18 64.3 0.1 0.00022 21.5 0.0 5.4 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 ORY96940.1 - 1.2e-11 44.0 0.1 2.6e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 ORY96940.1 - 6.4e-11 41.8 2.0 0.0059 15.6 0.0 3.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY96940.1 - 1.3e-06 27.4 0.4 0.00062 18.5 0.2 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ORY96940.1 - 0.0015 17.6 0.5 1.1 8.1 0.1 3.2 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 ORY96940.1 - 0.003 16.4 0.1 2.9 6.5 0.0 3.1 3 0 0 3 3 3 2 Nup133 N terminal like Hira PF07569.11 ORY96940.1 - 0.02 14.6 0.4 2.1 8.0 0.1 2.9 2 0 0 2 2 2 0 TUP1-like enhancer of split LisH PF08513.11 ORY96940.1 - 0.033 14.2 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 LisH PQQ_3 PF13570.6 ORY96940.1 - 0.13 12.8 1.5 0.85 10.2 0.0 3.1 4 1 0 4 4 3 0 PQQ-like domain WD40_like PF17005.5 ORY96940.1 - 0.16 11.3 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain MFS_1_like PF12832.7 ORY96941.1 - 1.6e-74 251.1 8.1 1.9e-74 250.8 8.1 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 ORY96941.1 - 6.2e-21 74.7 29.8 2.2e-15 56.5 5.5 3.5 1 1 3 4 4 4 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 ORY96941.1 - 3.7e-15 55.8 3.8 3.7e-15 55.8 3.8 2.5 2 1 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 ORY96941.1 - 1.1e-05 24.4 6.0 1.1e-05 24.4 6.0 2.6 2 1 0 2 2 2 1 LacY proton/sugar symporter OATP PF03137.20 ORY96941.1 - 0.019 13.3 0.1 0.019 13.3 0.1 3.2 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ceramidase PF05875.12 ORY96941.1 - 0.052 13.0 1.9 0.13 11.6 1.9 1.7 1 1 0 1 1 1 0 Ceramidase DUF4803 PF16061.5 ORY96942.1 - 0.14 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) KDZ PF18758.1 ORY96943.1 - 2.9e-27 95.7 0.1 3.5e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Ribosomal_L27 PF01016.19 ORY96944.1 - 5.1e-40 135.4 0.8 6.1e-40 135.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein zf-H2C2_2 PF13465.6 ORY96945.1 - 1.8e-07 31.2 6.7 1.1e-06 28.8 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 ORY96945.1 - 0.0022 18.6 5.4 0.0096 16.5 1.0 4.2 3 2 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 ORY96945.1 - 0.0033 17.8 0.1 0.0033 17.8 0.1 3.9 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf_ZIC PF18366.1 ORY96945.1 - 0.0035 17.4 8.3 4 7.6 0.0 4.0 2 2 1 3 3 3 2 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 ORY96945.1 - 0.014 16.2 0.1 0.014 16.2 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY96945.1 - 0.19 11.8 4.3 0.69 10.0 0.7 2.5 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORY96945.1 - 0.37 11.1 3.5 4.9 7.5 0.2 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY96945.1 - 1.5 8.9 0.0 1.5 8.9 0.0 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger NOA36 PF06524.12 ORY96945.1 - 1.9 7.7 14.9 0.015 14.6 6.5 1.9 2 0 0 2 2 2 0 NOA36 protein DS PF01916.17 ORY96946.1 - 1.1e-134 448.2 0.0 1.2e-134 448.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PXA PF02194.15 ORY96947.1 - 1e-46 159.2 0.0 5.2e-46 156.9 0.0 2.3 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 ORY96947.1 - 1.1e-27 96.9 0.4 1.1e-27 96.9 0.4 3.2 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 ORY96947.1 - 1e-17 64.2 0.0 1e-17 64.2 0.0 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 ORY96947.1 - 1e-15 58.0 2.1 3.2e-15 56.4 0.6 2.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Rbsn PF11464.8 ORY96947.1 - 0.00063 19.4 5.9 0.0017 18.0 5.9 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Isy1 PF06246.12 ORY96947.1 - 0.0011 18.6 0.3 0.0011 18.6 0.3 3.1 3 1 0 3 3 3 1 Isy1-like splicing family CHASE7 PF17151.4 ORY96947.1 - 0.069 12.7 0.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Periplasmic sensor domain Imm3 PF14425.6 ORY96947.1 - 0.32 11.1 2.6 1.1 9.4 2.6 1.9 1 0 0 1 1 1 0 Immunity protein Imm3 Metallophos PF00149.28 ORY96948.1 - 1.3e-19 71.5 0.0 3.3e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 ORY96948.1 - 1.4e-06 28.8 0.2 4.7e-06 27.1 0.2 2.0 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 ORY96948.1 - 3.5e-05 24.6 0.1 0.00013 22.7 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Polyketide_cyc2 PF10604.9 ORY96949.1 - 0.00025 21.3 1.1 0.033 14.4 0.0 2.1 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ORY96949.1 - 0.00096 19.4 6.2 0.0018 18.5 5.0 2.1 1 1 1 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport TFIIA PF03153.13 ORY96949.1 - 0.059 13.4 9.3 0.072 13.1 9.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY96949.1 - 0.25 10.9 10.9 0.43 10.1 10.9 1.4 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 ORY96949.1 - 0.66 8.7 7.2 0.88 8.3 7.2 1.3 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 ORY96949.1 - 1.1 8.0 6.6 1.2 7.8 4.0 2.0 2 0 0 2 2 2 0 Presenilin Sel1 PF08238.12 ORY96951.1 - 7.9e-19 67.7 20.1 0.00024 21.7 0.0 8.1 7 2 1 8 8 8 5 Sel1 repeat RNA12 PF10443.9 ORY96952.1 - 2.4e-114 382.5 0.2 1.9e-72 244.4 0.1 2.1 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 ORY96952.1 - 1.1e-09 38.5 1.4 1.7e-08 34.7 0.1 3.1 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 ORY96952.1 - 1.6e-07 31.0 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 ORY96952.1 - 0.00011 22.6 0.0 0.00027 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY96952.1 - 0.0025 18.1 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY96952.1 - 0.0028 17.7 0.0 0.012 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORY96952.1 - 0.019 14.2 0.2 0.064 12.4 0.0 1.9 2 1 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 ORY96952.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 ORY96952.1 - 0.062 13.7 0.0 5.1 7.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA PF00004.29 ORY96952.1 - 0.075 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORY96952.1 - 0.095 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 ORY96952.1 - 0.16 11.5 0.0 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HATPase_c PF02518.26 ORY96953.1 - 4e-26 91.7 0.2 1.1e-25 90.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 ORY96953.1 - 7e-24 83.9 2.8 2.8e-15 56.4 0.2 3.5 3 0 0 3 3 3 2 PAS fold Response_reg PF00072.24 ORY96953.1 - 2.9e-19 69.3 0.0 6.2e-18 65.0 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORY96953.1 - 9.7e-18 64.0 0.4 2.6e-17 62.6 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY96953.1 - 2.8e-14 53.3 0.0 7.6e-10 39.0 0.1 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY96953.1 - 6.9e-12 45.5 0.0 2.8e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORY96953.1 - 2.3e-11 43.7 2.8 1.3e-05 25.2 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 ORY96953.1 - 0.0018 18.2 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain NEMP PF10225.9 ORY96953.1 - 4.8 6.8 4.9 11 5.6 4.9 1.6 1 0 0 1 1 1 0 NEMP family Spt20 PF12090.8 ORY96953.1 - 5 6.7 31.7 0.029 14.0 19.8 2.7 3 0 0 3 3 3 0 Spt20 family TERB2 PF15101.6 ORY96953.1 - 5.9 6.9 14.9 0.54 10.3 6.8 2.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Roughex PF06020.11 ORY96953.1 - 7.5 5.5 11.5 25 3.8 11.5 1.9 1 0 0 1 1 1 0 Drosophila roughex protein MPM1 PF17234.2 ORY96953.1 - 9.4 6.5 12.4 13 6.0 5.7 2.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 CWC25 PF12542.8 ORY96954.1 - 5.7e-25 88.2 0.4 5.7e-25 88.2 0.4 3.1 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 ORY96954.1 - 2.8e-14 53.0 14.3 2.8e-14 53.0 14.3 4.3 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PRP38_assoc PF12871.7 ORY96954.1 - 0.011 16.3 36.2 0.011 16.3 36.2 2.8 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Aa_trans PF01490.18 ORY96955.1 - 2.2e-54 184.8 27.3 2.7e-54 184.4 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORY96955.1 - 0.0027 16.6 13.3 0.0027 16.6 13.3 2.5 2 1 0 2 2 2 1 Spore germination protein zf-MIZ PF02891.20 ORY96956.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TFIIA PF03153.13 ORY96956.1 - 0.41 10.6 62.1 0.63 10.0 62.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf70 PF17382.2 ORY96958.1 - 9.9 6.7 10.8 18 5.9 5.5 2.1 1 1 0 2 2 2 0 Uncharacterized Ycf70-like RHD3 PF05879.12 ORY96959.1 - 3.4e-250 832.3 9.3 1.8e-217 724.1 4.8 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 ORY96959.1 - 7.4e-07 29.4 0.4 3e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY96959.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 ORY96959.1 - 2.9e-06 26.8 0.3 6.7e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 ORY96959.1 - 0.002 18.4 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 ORY96959.1 - 0.04 13.2 1.8 0.23 10.7 0.1 2.5 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 ORY96959.1 - 0.049 13.5 0.2 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase DUF4566 PF15130.6 ORY96959.1 - 0.095 12.1 0.9 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) FeoB_N PF02421.18 ORY96959.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B ELM2 PF01448.24 ORY96959.1 - 0.16 12.8 1.6 22 5.9 1.5 3.0 2 1 0 2 2 2 0 ELM2 domain SDA1 PF05285.12 ORY96960.1 - 2.6 7.4 14.0 2.9 7.2 14.0 1.0 1 0 0 1 1 1 0 SDA1 Spt20 PF12090.8 ORY96960.1 - 3.1 7.4 17.3 3.9 7.0 17.3 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 ORY96960.1 - 3.9 6.5 12.5 5.4 6.0 12.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Herpes_LMP1 PF05297.11 ORY96960.1 - 4.4 6.4 5.3 5.1 6.2 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1387 PF07139.11 ORY96960.1 - 5.1 6.7 13.2 5.4 6.7 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF4795 PF16043.5 ORY96963.1 - 0.022 14.3 2.0 0.039 13.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) GET2 PF08690.10 ORY96963.1 - 0.027 14.1 7.6 0.076 12.7 7.6 1.7 1 0 0 1 1 1 0 GET complex subunit GET2 TMF_TATA_bd PF12325.8 ORY96963.1 - 0.2 11.9 5.5 0.38 11.0 5.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Not3 PF04065.15 ORY96963.1 - 0.25 10.7 3.7 0.43 10.0 3.7 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component AAA_32 PF13654.6 ORY96963.1 - 1.2 7.8 6.4 1.7 7.3 6.4 1.1 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 ORY96963.1 - 2.3 8.1 21.7 0.11 12.5 12.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SHE3 PF17078.5 ORY96963.1 - 4 7.1 7.1 4.6 6.9 1.6 2.0 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 gag-asp_proteas PF13975.6 ORY96966.1 - 6e-09 36.4 0.0 1.6e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY96966.1 - 4.4e-08 33.7 0.0 1.1e-07 32.4 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 ORY96966.1 - 5.6e-05 22.9 0.0 9.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 ORY96966.1 - 0.0048 16.7 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease hGDE_central PF14702.6 ORY96967.1 - 0.043 13.5 0.7 0.048 13.3 0.7 1.1 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme LMBR1 PF04791.16 ORY96967.1 - 0.2 10.5 2.7 0.24 10.3 2.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Asn_synthase PF00733.21 ORY96968.1 - 8.8e-95 318.4 1.4 1.1e-58 199.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORY96968.1 - 2.9e-42 143.5 0.0 4.9e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY96968.1 - 2.7e-34 118.2 0.0 6.4e-34 117.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORY96968.1 - 3.1e-08 33.3 0.0 6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ORY96968.1 - 0.014 14.5 0.0 0.037 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 ORY96968.1 - 0.04 13.4 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORY96968.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase BAR PF03114.18 ORY96969.1 - 7.6e-29 101.0 5.4 7.6e-29 101.0 5.4 1.4 1 1 0 1 1 1 1 BAR domain Seryl_tRNA_N PF02403.22 ORY96969.1 - 0.02 15.1 2.0 0.84 9.9 0.9 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PolyA_pol_arg_C PF12626.7 ORY96969.1 - 0.46 10.5 3.1 0.66 10.0 1.7 2.0 1 1 1 2 2 2 0 Polymerase A arginine-rich C-terminus PIN_8 PF18476.1 ORY96969.1 - 0.69 9.7 4.9 1.1 9.0 2.9 2.3 2 1 0 2 2 2 0 PIN like domain DUF5344 PF17279.2 ORY96969.1 - 1.9 9.1 10.1 0.4 11.3 1.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF948 PF06103.11 ORY96969.1 - 3 8.2 5.3 17 5.8 0.0 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 ORY96969.1 - 3.4 8.3 6.8 4.7 7.9 1.2 2.7 3 0 0 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 ORY96969.1 - 9.8 6.2 8.2 5.3 7.1 0.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Helitron_like_N PF14214.6 ORY97159.1 - 0.036 14.3 0.4 0.077 13.2 0.2 1.7 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus Calci_bind_CcbP PF11535.8 ORY97162.1 - 0.18 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcium binding UDG PF03167.19 ORY97163.1 - 1.1e-15 58.0 0.0 1.4e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Rrp15p PF07890.12 ORY97164.1 - 0.12 12.7 0.5 0.22 11.9 0.5 1.5 1 0 0 1 1 1 0 Rrp15p FAR1 PF03101.15 ORY97165.1 - 0.00012 22.7 2.1 0.00015 22.4 1.2 1.6 1 1 0 1 1 1 1 FAR1 DNA-binding domain DUF2515 PF10720.9 ORY97165.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) NPH3 PF03000.14 ORY97167.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 NPH3 family DUF4218 PF13960.6 ORY97169.1 - 0.00026 20.6 0.2 0.0011 18.5 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 ORY97169.1 - 0.0008 18.7 0.0 0.0018 17.5 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 MIEAP PF16026.5 ORY97171.1 - 0.025 14.8 0.5 0.033 14.4 0.5 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein DMSP_lyase PF16867.5 ORY97173.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF4218 PF13960.6 ORY97174.1 - 7.5e-05 22.3 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PSK_trans_fac PF07704.11 ORY97174.1 - 0.13 13.0 1.7 0.5 11.2 0.1 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor NUDE_C PF04880.13 ORY97174.1 - 0.88 10.0 9.3 0.22 12.0 2.5 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Chorion_2 PF03964.15 ORY97174.1 - 6.4 7.7 7.1 3.4 8.5 0.4 3.0 3 0 0 3 3 3 0 Chorion family 2 YEATS PF03366.16 ORY97176.1 - 1.7e-17 63.1 0.0 3.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 YEATS family Nucleo_P87 PF07267.11 ORY97176.1 - 0.58 8.9 6.1 0.85 8.4 6.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LUC7 PF03194.15 ORY97177.1 - 5.2e-09 36.2 8.9 6.1e-09 35.9 8.9 1.1 1 0 0 1 1 1 1 LUC7 N_terminus OrsD PF12013.8 ORY97177.1 - 0.45 11.0 6.5 0.13 12.7 2.6 2.0 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D CNOT1_CAF1_bind PF16415.5 ORY97178.1 - 5.6e-71 238.5 6.8 6.7e-71 238.3 4.3 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Not1 PF04054.15 ORY97178.1 - 1.2e-60 205.4 3.8 1.6e-34 119.5 0.1 2.7 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 CNOT1_TTP_bind PF16417.5 ORY97178.1 - 2.6e-41 140.9 0.2 1.2e-40 138.8 0.2 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 ORY97178.1 - 4.3e-30 104.8 2.7 4.3e-30 104.8 2.7 2.3 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3819 PF12842.7 ORY97178.1 - 7.9e-17 61.6 0.3 2.5e-16 59.9 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) PI_PP_C PF18365.1 ORY97178.1 - 0.074 13.0 0.1 0.38 10.7 0.1 2.2 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain RRM_1 PF00076.22 ORY97179.1 - 3.1e-59 196.7 0.4 1.6e-18 66.2 0.0 6.0 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY97179.1 - 5.9e-07 29.1 0.0 0.0008 19.0 0.0 3.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 ORY97179.1 - 0.0035 16.8 43.8 0.0035 16.8 43.8 3.2 3 0 0 3 3 3 1 BUD22 RRM_Rrp7 PF17799.1 ORY97179.1 - 0.0095 15.7 0.0 9.1 6.1 0.0 3.4 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 ORY97179.1 - 0.025 14.4 0.0 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif SDA1 PF05285.12 ORY97179.1 - 4.7 6.6 65.4 0.096 12.1 56.4 2.5 2 1 0 2 2 2 0 SDA1 Fer2 PF00111.27 ORY97180.1 - 8.7e-12 44.8 1.0 1.2e-11 44.4 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GATase_6 PF13522.6 ORY97181.1 - 3.8e-16 59.5 0.0 7.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY97181.1 - 1.5e-13 50.7 0.0 4.2e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY97181.1 - 5.3e-07 28.8 0.0 1.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 ORY97181.1 - 2.1e-06 27.3 0.0 4.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NUDIX PF00293.28 ORY97182.1 - 2.1e-09 37.5 0.1 2.6e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 ORY97183.1 - 2.5e-19 69.6 1.0 3.1e-19 69.3 1.0 1.1 1 0 0 1 1 1 1 NUDIX domain EMG1 PF03587.14 ORY97184.1 - 1.8e-67 226.8 0.0 2.1e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pkinase PF00069.25 ORY97185.1 - 2e-48 165.1 0.0 2.5e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97185.1 - 2.2e-33 115.6 0.0 2.7e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97185.1 - 0.00059 19.2 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY97185.1 - 0.0026 17.7 0.1 0.44 10.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY97185.1 - 0.0036 16.3 0.0 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY97185.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 ORY97185.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zip PF02535.22 ORY97186.1 - 1.5e-29 103.3 5.9 1.5e-29 103.3 5.9 2.6 1 1 2 3 3 3 1 ZIP Zinc transporter ESM4 PF15952.5 ORY97186.1 - 0.00034 21.1 1.3 0.00034 21.1 1.3 1.9 2 0 0 2 2 2 1 Enhancer of split M4 family Connexin PF00029.19 ORY97186.1 - 0.015 15.1 0.7 0.59 9.8 0.2 2.2 2 0 0 2 2 2 0 Connexin Sec62 PF03839.16 ORY97186.1 - 1.2 8.7 2.9 8.8 5.8 0.0 2.5 3 0 0 3 3 3 0 Translocation protein Sec62 Pap_E4 PF02711.14 ORY97186.1 - 1.5 9.9 7.3 0.1 13.6 1.6 1.9 2 0 0 2 2 2 0 E4 protein FHA PF00498.26 ORY97187.1 - 1e-08 35.4 0.3 1.9e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 ORY97187.1 - 0.0062 16.8 0.0 0.016 15.5 0.0 1.6 2 0 0 2 2 2 1 FHA domain Clathrin PF00637.20 ORY97188.1 - 3.2e-202 662.5 51.3 7e-36 123.2 0.5 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 ORY97188.1 - 5.5e-31 105.4 0.2 3.1e-06 27.2 0.0 6.5 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 ORY97188.1 - 1.8e-30 104.6 2.0 8.7e-30 102.4 0.0 3.3 4 0 0 4 4 3 1 Clathrin-H-link Clathrin-link PF09268.10 ORY97188.1 - 1.8e-10 40.0 0.0 4.8e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 ORY97188.1 - 7.8e-08 31.8 5.0 0.025 13.6 0.1 4.5 4 0 0 4 4 4 2 Coatomer WD associated region TPR_14 PF13428.6 ORY97188.1 - 6.8e-05 23.4 7.0 0.22 12.4 0.2 7.9 10 0 0 10 10 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97188.1 - 0.00032 20.4 0.3 1.8 8.5 0.1 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97188.1 - 0.0055 16.7 6.1 4.3 7.7 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Nucleoporin_N PF08801.11 ORY97188.1 - 0.014 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like PQQ PF01011.21 ORY97188.1 - 0.088 12.8 0.3 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat TPR_8 PF13181.6 ORY97188.1 - 0.093 13.0 3.3 11 6.5 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 ORY97188.1 - 0.099 12.9 4.5 29 5.2 0.0 6.1 7 0 0 7 7 7 0 PPR repeat TPR_7 PF13176.6 ORY97188.1 - 0.16 12.1 9.4 3.2 8.0 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY97188.1 - 0.26 11.2 1.0 57 3.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97188.1 - 0.35 11.2 7.2 20 5.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF202 PF02656.15 ORY97189.1 - 8.2e-14 51.8 3.6 8.2e-14 51.8 3.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Sarcolipin PF05366.11 ORY97189.1 - 2.6 7.8 5.7 3 7.6 0.1 3.0 3 0 0 3 3 3 0 Sarcolipin Alg14 PF08660.11 ORY97190.1 - 1.5e-54 184.5 0.0 2e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.20 ORY97190.1 - 0.022 14.8 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain CoA_binding_3 PF13727.6 ORY97190.1 - 0.061 13.3 0.1 0.091 12.8 0.1 1.3 1 0 0 1 1 1 0 CoA-binding domain Fungal_trans PF04082.18 ORY97191.1 - 9.8e-23 80.5 0.0 9.1e-22 77.3 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY97191.1 - 3.9e-09 36.5 11.7 6.3e-09 35.8 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF913 PF06025.12 ORY97191.1 - 0.27 10.2 1.4 0.41 9.6 1.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RP-C_C PF11800.8 ORY97191.1 - 0.79 9.8 3.9 1.5 8.9 3.9 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region LRR_6 PF13516.6 ORY97193.1 - 5.6e-06 26.0 4.4 6 7.2 0.0 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 ORY97193.1 - 1.5e-05 25.3 0.0 0.12 12.8 0.0 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY97193.1 - 0.00019 21.3 1.7 0.0003 20.6 0.6 2.1 2 0 0 2 2 2 1 F-box-like YafQ_toxin PF15738.5 ORY97193.1 - 0.012 15.9 0.3 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ LRR_1 PF00560.33 ORY97193.1 - 0.14 12.8 5.2 1.1e+02 3.9 0.7 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat Proteasome PF00227.26 ORY97194.1 - 7.1e-35 120.2 0.1 1e-34 119.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Asp PF00026.23 ORY97196.1 - 3.9e-25 88.9 0.0 8.2e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY97196.1 - 5.3e-08 33.3 0.3 1.4e-07 31.9 0.3 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MG4 PF17789.1 ORY97196.1 - 0.039 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Macroglobulin domain MG4 Kelch_5 PF13854.6 ORY97197.1 - 6.3e-08 32.4 0.3 0.021 14.8 0.1 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 ORY97197.1 - 0.013 15.8 1.2 2.3 8.6 0.1 3.8 3 1 0 3 3 3 0 Kelch motif ASC PF00858.24 ORY97197.1 - 0.051 12.5 0.3 3.2 6.6 0.0 2.5 2 1 0 2 2 2 0 Amiloride-sensitive sodium channel Kelch_4 PF13418.6 ORY97197.1 - 0.11 12.5 0.2 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY97197.1 - 0.45 10.9 6.1 1.5 9.2 0.1 4.0 3 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY97197.1 - 1 9.5 2.9 16 5.7 0.1 3.4 3 1 0 3 3 3 0 Kelch motif B56 PF01603.20 ORY97198.1 - 3.1e-193 642.4 8.7 4e-193 642.0 8.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PfkB PF00294.24 ORY97199.1 - 8.7e-34 117.2 0.0 1.3e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ldh_1_C PF02866.18 ORY97200.1 - 1.7e-50 171.2 0.1 5.8e-50 169.5 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORY97200.1 - 2.6e-45 154.0 0.0 4.2e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ORY97200.1 - 1.9e-06 27.1 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORY97200.1 - 0.036 14.5 0.6 0.12 12.8 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 ORY97200.1 - 0.068 12.7 0.1 0.49 9.9 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase PQ-loop PF04193.14 ORY97202.1 - 1.6e-24 85.4 11.7 3.1e-15 55.7 0.6 2.8 3 0 0 3 3 3 2 PQ loop repeat Pkinase PF00069.25 ORY97203.1 - 2.1e-58 197.8 0.0 3.4e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97203.1 - 1.5e-31 109.7 0.0 2.2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY97203.1 - 1.2e-09 38.7 0.7 1.2e-09 38.7 0.7 3.2 2 1 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 ORY97203.1 - 0.00035 20.3 0.0 0.74 9.4 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORY97203.1 - 0.0024 16.7 0.5 0.0048 15.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PX PF00787.24 ORY97203.1 - 0.0071 16.3 4.1 0.016 15.2 0.1 3.4 3 1 0 3 3 3 1 PX domain Kinase-like PF14531.6 ORY97203.1 - 0.08 12.2 0.0 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DAGK_acc PF00609.19 ORY97204.1 - 2e-16 60.7 0.0 3.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 ORY97204.1 - 0.00014 21.4 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain MFS_1 PF07690.16 ORY97205.1 - 2.1e-31 109.2 51.6 1.7e-20 73.3 29.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SWIRM PF04433.17 ORY97206.1 - 0.0009 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Cwf_Cwc_15 PF04889.12 ORY97206.1 - 0.32 10.7 7.6 0.52 10.0 7.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 ORY97206.1 - 1.3 8.4 8.2 1.9 7.8 8.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 ORY97206.1 - 1.6 6.9 5.8 2.2 6.5 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 ORY97206.1 - 2.6 9.1 13.8 6.3 7.8 13.8 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.13 ORY97206.1 - 7.9 6.3 7.8 12 5.7 7.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region HLH PF00010.26 ORY97207.1 - 7.3e-18 64.3 0.7 1.7e-17 63.1 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Svf1_C PF17187.4 ORY97208.1 - 2.5e-50 170.6 3.4 2.5e-50 170.5 1.7 1.8 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORY97208.1 - 3.1e-36 124.9 1.4 7e-36 123.7 1.4 1.6 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain SUIM_assoc PF16619.5 ORY97210.1 - 6.7 6.9 26.7 0.93 9.6 5.3 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Frag1 PF10277.9 ORY97211.1 - 8e-35 120.4 13.4 8e-35 120.4 13.4 3.0 3 2 0 3 3 3 1 Frag1/DRAM/Sfk1 family Glyco_transf_11 PF01531.16 ORY97212.1 - 7.4e-06 25.4 1.8 0.48 9.6 0.1 3.9 4 0 0 4 4 4 3 Glycosyl transferase family 11 SIP1 PF04938.12 ORY97213.1 - 7.4e-36 123.9 0.1 8.7e-36 123.7 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TPR_1 PF00515.28 ORY97214.1 - 5.4e-26 89.3 0.1 1.8e-08 33.9 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97214.1 - 4.1e-21 73.3 1.1 9e-07 28.6 0.2 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY97214.1 - 1.5e-19 69.4 0.1 3.4e-07 29.8 0.0 4.9 3 1 1 4 4 4 4 TPR repeat TPR_17 PF13431.6 ORY97214.1 - 5.2e-18 64.1 0.3 0.00071 19.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY97214.1 - 1.8e-17 63.7 0.3 0.00024 21.7 0.0 4.7 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97214.1 - 6.3e-16 57.7 2.5 1.7e-05 25.2 0.0 6.0 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY97214.1 - 2.1e-15 55.5 0.0 0.00046 20.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY97214.1 - 1.5e-12 47.9 0.2 0.00083 19.8 0.4 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY97214.1 - 1.6e-11 44.4 0.2 0.011 16.1 0.1 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97214.1 - 7.5e-10 39.0 0.8 0.0036 17.6 0.5 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY97214.1 - 3.9e-07 29.6 0.7 0.2 11.8 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY97214.1 - 5.9e-07 29.5 0.2 0.33 11.1 0.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY97214.1 - 5.2e-06 26.6 2.1 0.0011 19.1 0.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY97214.1 - 5.9e-05 23.4 0.1 27 5.7 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY97214.1 - 0.00026 20.3 0.1 0.15 11.2 0.1 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 ORY97214.1 - 0.00074 19.5 0.1 1.3 9.2 0.0 3.1 3 0 0 3 3 2 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 ORY97214.1 - 0.03 14.2 4.5 0.43 10.5 0.4 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4248 PF14053.6 ORY97214.1 - 0.043 13.9 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) DUF1641 PF07849.11 ORY97214.1 - 0.095 12.6 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_3 PF07720.12 ORY97214.1 - 0.12 12.4 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY97217.1 - 1.1e-07 31.6 0.2 3.7e-07 29.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 ORY97217.1 - 0.0031 17.5 0.1 0.008 16.2 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.33 ORY97217.1 - 0.022 14.7 1.4 0.096 12.6 0.1 2.8 3 0 0 3 3 3 0 F-box domain TPR_11 PF13414.6 ORY97217.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 TPR repeat NOG1_N PF17835.1 ORY97218.1 - 2.4e-57 193.4 1.7 6.6e-57 191.9 1.7 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 ORY97218.1 - 1.9e-28 98.0 0.2 1.9e-28 98.0 0.2 2.1 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 ORY97218.1 - 7.1e-28 96.4 1.9 1.7e-27 95.1 1.9 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 ORY97218.1 - 9.3e-19 67.6 0.0 2e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY97218.1 - 1.2e-10 41.2 0.0 2.7e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY97218.1 - 0.00052 20.0 0.1 0.31 10.9 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY97218.1 - 0.002 17.7 0.3 0.14 11.7 0.2 3.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORY97218.1 - 0.0022 17.3 0.0 0.0046 16.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 ORY97218.1 - 0.0033 17.8 0.2 0.051 14.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 ORY97218.1 - 0.0069 16.6 0.0 0.06 13.6 0.0 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORY97218.1 - 0.0077 16.3 2.6 0.71 9.9 0.0 3.5 3 1 1 4 4 4 1 Dynamin family AAA_18 PF13238.6 ORY97218.1 - 0.099 13.2 0.1 3 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 ORY97218.1 - 0.11 11.7 4.9 0.2 10.8 0.1 3.1 3 1 1 4 4 4 0 G-protein alpha subunit HMG_CoA_synt_C PF08540.10 ORY97219.1 - 3.3e-100 335.3 3.2 4.4e-100 334.9 3.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 ORY97219.1 - 4.2e-88 293.7 0.4 6.2e-88 293.2 0.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Guanylate_cyc_2 PF09778.9 ORY97221.1 - 1.6e-66 223.7 0.8 1.8e-66 223.5 0.8 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 ORY97221.1 - 3.3e-07 31.0 0.2 0.0065 17.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.15 ORY97221.1 - 6.2e-06 26.1 0.2 0.0011 18.8 0.0 3.0 3 0 0 3 3 3 1 Peptidase C39 family Peptidase_C70 PF12385.8 ORY97221.1 - 0.026 14.5 0.1 0.066 13.2 0.0 1.7 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 hnRNP_Q_AcD PF18360.1 ORY97222.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain STAC2_u1 PF16664.5 ORY97224.1 - 0.045 14.2 1.3 0.07 13.6 1.2 1.4 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Mito_carr PF00153.27 ORY97225.1 - 2e-64 213.6 1.6 1e-22 79.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RFC1 PF08519.12 ORY97226.1 - 3.8e-22 79.1 0.0 8e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 ORY97226.1 - 1.2e-14 54.9 0.1 2.4e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY97226.1 - 1.4e-07 31.6 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 ORY97226.1 - 0.00013 21.7 0.0 0.00073 19.3 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ORY97226.1 - 0.00016 21.7 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY97226.1 - 0.00019 21.4 0.1 0.015 15.2 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 ORY97226.1 - 0.0007 20.1 0.0 0.0021 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY97226.1 - 0.00073 20.0 0.0 0.028 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY97226.1 - 0.003 17.8 0.0 0.015 15.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 ORY97226.1 - 0.0065 16.5 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY97226.1 - 0.027 14.8 0.0 0.096 13.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ORY97226.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY97226.1 - 0.04 14.1 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY97226.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY97226.1 - 0.1 12.9 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 ORY97227.1 - 1.3e-43 149.3 29.1 1.3e-43 149.3 29.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY97227.1 - 3.6e-09 36.0 8.6 3.6e-09 36.0 8.6 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2614 PF11023.8 ORY97227.1 - 0.015 15.4 1.6 0.054 13.6 1.6 2.0 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2615 PF11027.8 ORY97227.1 - 0.69 10.1 2.6 21 5.3 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2615) Keratin_assoc PF09775.9 ORY97227.1 - 1 9.1 6.0 0.24 11.0 0.3 2.5 2 1 0 2 2 2 0 Keratinocyte-associated protein 2 MFS_1 PF07690.16 ORY97228.1 - 3e-45 154.7 26.8 3e-45 154.7 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY97228.1 - 2.2e-12 46.6 5.8 2.2e-12 46.6 5.8 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter ABC2_membrane_5 PF13346.6 ORY97228.1 - 0.00063 19.4 1.0 0.00063 19.4 1.0 3.3 5 0 0 5 5 5 1 ABC-2 family transporter protein DUF2614 PF11023.8 ORY97228.1 - 0.04 14.0 2.2 0.12 12.5 2.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain Glyco_transf_15 PF01793.16 ORY97229.1 - 3.8e-111 371.4 6.0 4.7e-111 371.1 6.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ceramidase_alk PF04734.13 ORY97230.1 - 6.5e-194 645.3 0.0 7.6e-194 645.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 ORY97230.1 - 6e-38 130.3 0.2 9.3e-38 129.7 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF3752 PF12572.8 ORY97231.1 - 3.4e-20 73.1 15.2 3.4e-20 73.1 15.2 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF3752) AA_permease_N PF08403.10 ORY97231.1 - 0.074 12.6 0.3 6.7 6.3 0.0 2.7 3 0 0 3 3 3 0 Amino acid permease N-terminal Lipase_GDSL PF00657.22 ORY97232.1 - 5.6e-14 52.6 0.0 7.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY97232.1 - 5.8e-12 46.4 0.1 8.4e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2610 PF11020.8 ORY97232.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) AMP-binding PF00501.28 ORY97233.1 - 2.1e-91 306.6 0.0 2.7e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY97233.1 - 1.3e-18 67.8 1.4 2.9e-18 66.6 1.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ORY97233.1 - 0.0041 16.0 0.0 0.045 12.6 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Molybdop_Fe4S4 PF04879.16 ORY97233.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain Kelch_5 PF13854.6 ORY97234.1 - 1.7e-11 43.9 6.6 0.00037 20.4 0.1 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 ORY97234.1 - 8.9e-11 41.3 3.5 1.4e-05 24.8 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 ORY97234.1 - 1.6e-10 40.8 8.8 9.2e-05 22.4 0.0 4.5 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY97234.1 - 1.2e-08 34.3 7.1 0.00078 19.0 0.5 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 ORY97234.1 - 2.2e-08 34.1 7.0 0.0058 16.9 0.2 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 ORY97234.1 - 6.7e-07 29.4 14.1 0.00064 19.9 0.2 4.5 4 1 1 5 5 5 2 Galactose oxidase, central domain DUF913 PF06025.12 ORY97235.1 - 0.28 10.1 2.6 0.29 10.1 2.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GTP_EFTU PF00009.27 ORY97237.1 - 8.8e-21 74.3 0.0 2.3e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY97237.1 - 5.7e-07 29.8 0.4 1.8e-06 28.3 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 ORY97237.1 - 0.00061 20.1 1.7 0.0021 18.3 1.7 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 ORY97237.1 - 0.0016 18.5 0.1 0.0063 16.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY97237.1 - 0.0086 15.8 0.2 11 5.7 0.0 3.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 ORY97237.1 - 0.12 12.6 0.2 16 5.7 0.1 3.0 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ecm29 PF13001.7 ORY97238.1 - 9e-145 483.1 1.2 1.9e-144 482.1 0.4 2.0 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 ORY97238.1 - 1.2e-10 40.7 16.7 0.021 15.0 0.0 11.6 13 0 0 13 13 13 3 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY97238.1 - 6.2e-06 26.7 11.6 0.01 16.4 0.0 7.1 8 1 0 8 8 8 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 ORY97238.1 - 0.00015 21.0 1.7 1.1 8.4 0.0 4.7 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 ORY97238.1 - 0.00037 20.9 9.9 8.1 7.1 0.0 8.7 12 1 0 12 12 12 1 HEAT-like repeat CCAP PF11105.8 ORY97238.1 - 0.064 13.2 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a CLASP_N PF12348.8 ORY97238.1 - 0.066 12.8 4.8 2.1 7.9 0.0 4.7 5 0 0 5 5 5 0 CLASP N terminal V4R PF02830.18 ORY97238.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 V4R domain RFC1 PF08519.12 ORY97238.1 - 0.094 12.9 0.2 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain RUN PF02759.19 ORY97238.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 RUN domain Ion_trans PF00520.31 ORY97239.1 - 2e-118 394.0 80.8 2.2e-32 112.2 8.8 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 ORY97239.1 - 5.3e-06 26.1 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 ORY97239.1 - 1.2e-05 24.2 0.4 1.2e-05 24.2 0.4 8.4 6 3 3 9 9 9 6 Polycystin cation channel RasGEF PF00617.19 ORY97240.1 - 4.5e-44 150.7 0.3 8.7e-44 149.8 0.0 1.6 2 0 0 2 2 2 1 RasGEF domain DUF4477 PF14780.6 ORY97241.1 - 6.8e-16 58.5 0.5 9e-16 58.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) ADK PF00406.22 ORY97242.1 - 2.8e-60 202.8 0.0 4e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY97242.1 - 4.4e-20 72.5 0.1 1.1e-19 71.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 ORY97242.1 - 8.9e-18 64.0 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 ORY97242.1 - 0.00033 21.2 0.0 0.00064 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY97242.1 - 0.039 14.1 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ORY97242.1 - 0.046 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase KxDL PF10241.9 ORY97242.1 - 0.21 11.9 0.4 0.48 10.7 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein eIF2A PF08662.11 ORY97243.1 - 2e-41 142.0 1.7 9.9e-35 120.2 0.1 5.4 3 3 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ORY97243.1 - 7.2e-06 25.7 0.0 2.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 ORY97243.1 - 0.00042 21.1 3.4 0.17 12.8 0.7 4.6 4 1 1 5 5 5 1 WD domain, G-beta repeat MciZ PF13072.6 ORY97243.1 - 0.12 12.2 0.3 0.44 10.4 0.3 2.0 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Peptidase_S8 PF00082.22 ORY97244.1 - 2.7e-45 154.9 0.7 4e-45 154.3 0.7 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 ORY97244.1 - 4.1e-09 36.3 0.0 1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 PA domain fn3_5 PF06280.12 ORY97244.1 - 1.3e-05 25.9 0.0 3.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain F-box-like PF12937.7 ORY97244.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like TPR_9 PF13371.6 ORY97244.1 - 0.0044 17.1 1.8 0.014 15.6 0.7 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 ORY97244.1 - 0.2 10.5 0.1 0.33 9.8 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Inhibitor_I9 PF05922.16 ORY97244.1 - 0.2 12.3 0.1 0.47 11.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I9 Syja_N PF02383.18 ORY97246.1 - 2.4e-80 270.2 0.3 4.3e-80 269.4 0.3 1.4 1 0 0 1 1 1 1 SacI homology domain BssB_TutG PF18512.1 ORY97247.1 - 0.029 14.2 0.0 8.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit DUF4115 PF13464.6 ORY97247.1 - 0.17 12.1 1.3 16 5.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) Fungal_trans PF04082.18 ORY97249.1 - 1.4e-30 106.2 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY97249.1 - 3.3e-09 36.7 10.2 6.4e-09 35.8 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S8 PF00082.22 ORY97251.1 - 6.1e-55 186.6 0.0 1.2e-54 185.6 0.0 1.5 1 1 0 1 1 1 1 Subtilase family PA PF02225.22 ORY97251.1 - 8.9e-13 48.1 0.2 2.5e-12 46.6 0.2 1.8 1 0 0 1 1 1 1 PA domain fn3_5 PF06280.12 ORY97251.1 - 7.4e-12 46.0 0.0 1.7e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain AP_endonuc_2 PF01261.24 ORY97251.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel MAS20 PF02064.15 ORY97252.1 - 1.8e-44 150.9 1.6 1.8e-44 150.9 1.6 1.5 2 0 0 2 2 2 1 MAS20 protein import receptor DUF4381 PF14316.6 ORY97252.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_S26 PF10502.9 ORY97253.1 - 4.4e-08 33.0 0.0 0.00029 20.6 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 ORY97253.1 - 1.5e-06 28.0 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Presenilin PF01080.17 ORY97254.1 - 0.21 10.3 13.1 0.29 9.8 13.1 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 ORY97254.1 - 4.5 5.3 10.9 5.3 5.1 10.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 ORY97254.1 - 8.4 5.1 6.0 11 4.7 6.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Beta_elim_lyase PF01212.21 ORY97255.1 - 1.2e-72 244.6 0.0 1.5e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORY97255.1 - 1.2e-06 27.9 0.0 2.8e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY97255.1 - 0.0096 15.3 0.1 0.018 14.4 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family PH PF00169.29 ORY97256.1 - 0.00023 21.6 0.6 0.00074 20.0 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 ORY97256.1 - 0.0066 16.9 1.6 0.012 16.0 0.1 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain Med19 PF10278.9 ORY97257.1 - 0.0022 17.9 18.0 1.3 8.9 0.0 2.3 2 1 0 2 2 2 2 Mediator of RNA pol II transcription subunit 19 Coilin_N PF15862.5 ORY97257.1 - 0.53 10.1 10.4 0.69 9.7 10.4 1.2 1 0 0 1 1 1 0 Coilin N-terminus RNA_polI_A34 PF08208.11 ORY97257.1 - 0.72 9.9 17.4 1 9.4 17.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PPR_2 PF13041.6 ORY97262.1 - 8.9e-62 205.1 7.1 1.3e-10 41.2 0.0 14.2 12 2 3 15 15 15 10 PPR repeat family PPR PF01535.20 ORY97262.1 - 2e-35 118.5 26.8 7.7e-05 22.7 0.0 16.8 20 0 0 20 20 20 7 PPR repeat PPR_3 PF13812.6 ORY97262.1 - 4.4e-29 100.3 0.6 0.00022 21.2 0.0 10.1 10 2 3 13 13 12 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY97262.1 - 9.3e-29 98.8 12.4 8.4e-05 22.2 0.0 13.4 16 1 1 17 17 17 5 PPR repeat PPR_long PF17177.4 ORY97262.1 - 1.3e-18 67.1 20.7 1.9e-05 24.1 0.3 7.2 3 3 3 7 7 7 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORY97262.1 - 1.2e-06 28.9 0.4 0.005 17.2 0.0 3.4 3 0 0 3 3 2 2 Mitochondrial ribonuclease P subunit (RPM2) SR-25 PF10500.9 ORY97262.1 - 0.0033 17.1 4.6 0.0055 16.3 4.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TPR_4 PF07721.14 ORY97262.1 - 0.02 15.5 12.3 6.1 7.8 1.1 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat KNOX1 PF03790.13 ORY97262.1 - 0.023 14.4 0.2 13 5.6 0.1 4.0 3 0 0 3 3 3 0 KNOX1 domain TPR_19 PF14559.6 ORY97262.1 - 0.047 14.2 0.1 0.047 14.2 0.1 10.2 10 2 3 13 13 13 0 Tetratricopeptide repeat Ribosomal_L38e PF01781.18 ORY97262.1 - 0.11 12.6 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Ribosomal L38e protein family TPR_12 PF13424.6 ORY97262.1 - 0.16 12.2 23.7 1.9 8.8 0.5 7.9 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97262.1 - 1.1 9.1 9.6 59 3.7 0.3 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1746 PF08508.10 ORY97263.1 - 2.7e-15 56.7 5.5 6.7e-15 55.4 5.5 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) ATG101 PF07855.12 ORY97264.1 - 2.1e-42 144.7 0.5 2.8e-42 144.3 0.5 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 LAMTOR PF15454.6 ORY97264.1 - 0.079 13.6 0.4 0.17 12.5 0.4 1.5 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Telomere_reg-2 PF10193.9 ORY97265.1 - 8.2e-19 68.1 0.0 8.2e-19 68.1 0.0 2.3 3 0 0 3 3 3 1 Telomere length regulation protein HORMA PF02301.18 ORY97265.1 - 0.059 13.0 0.1 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 HORMA domain CDC45 PF02724.14 ORY97265.1 - 0.14 10.4 2.3 0.22 9.8 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Osteopontin PF00865.18 ORY97265.1 - 3.4 7.1 16.6 5.5 6.4 16.6 1.2 1 0 0 1 1 1 0 Osteopontin Peptidase_C97 PF05903.14 ORY97266.1 - 6.1e-43 146.3 0.0 1e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 ORY97266.1 - 3.7e-37 128.1 0.8 3.7e-37 128.1 0.8 1.6 2 0 0 2 2 2 1 PUL domain Thioredoxin PF00085.20 ORY97266.1 - 1.3e-14 54.0 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY97266.1 - 4.5e-07 30.3 0.0 1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ORY97266.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY97266.1 - 0.0003 20.5 0.1 0.00085 19.1 0.0 1.7 2 0 0 2 2 2 1 Redoxin DUF2847 PF11009.8 ORY97266.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) OST3_OST6 PF04756.13 ORY97266.1 - 0.0023 17.4 0.1 0.0037 16.6 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 ORY97266.1 - 0.0073 16.5 0.0 2.7 8.1 0.0 2.7 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.6 ORY97266.1 - 0.0089 15.9 0.7 0.036 13.9 0.1 2.3 2 1 1 3 3 3 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 ORY97266.1 - 0.026 14.9 0.1 0.16 12.4 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 ORY97266.1 - 0.031 14.5 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 ORY97266.1 - 0.042 13.6 0.2 1 9.1 0.1 2.8 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Ribosomal_60s PF00428.19 ORY97266.1 - 0.048 14.3 0.1 0.048 14.3 0.1 2.8 2 1 1 3 3 2 0 60s Acidic ribosomal protein T4_deiodinase PF00837.17 ORY97266.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Iodothyronine deiodinase HyaE PF07449.11 ORY97266.1 - 0.081 12.9 0.2 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE FliC_SP PF12613.8 ORY97266.1 - 4.5 7.9 9.1 0.71 10.4 4.3 2.2 2 0 0 2 2 2 0 Flagellin structural protein Med26 PF08711.11 ORY97267.1 - 2.3e-13 50.0 0.0 6.5e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4192 PF13830.6 ORY97267.1 - 4.2 7.3 7.1 9.5 6.2 6.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) TFR_dimer PF04253.15 ORY97268.1 - 4.7e-29 100.9 0.2 8.1e-29 100.2 0.2 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORY97268.1 - 7e-24 84.6 0.0 1.2e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY97268.1 - 1.3e-10 41.1 0.0 2.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORY97268.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ORY97268.1 - 0.0097 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Pkinase_C PF00433.24 ORY97269.1 - 0.0063 17.2 0.6 0.046 14.4 0.6 2.7 1 1 0 1 1 1 1 Protein kinase C terminal domain Mito_carr PF00153.27 ORY97270.1 - 1.5e-61 204.3 0.5 2e-21 75.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FGGY_C PF02782.16 ORY97270.1 - 0.018 14.7 0.1 0.91 9.2 0.0 2.4 2 1 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain WW PF00397.26 ORY97272.1 - 2.3e-06 27.6 3.0 5.1e-06 26.5 3.0 1.6 1 0 0 1 1 1 1 WW domain ubiquitin PF00240.23 ORY97274.1 - 0.00035 20.2 0.0 0.0017 18.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family DUF2071 PF09844.9 ORY97274.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) Aldedh PF00171.22 ORY97275.1 - 3.3e-184 612.7 0.2 3.8e-184 612.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY97275.1 - 0.053 13.0 0.1 0.28 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) adh_short_C2 PF13561.6 ORY97276.1 - 4.5e-54 183.5 0.0 5.4e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY97276.1 - 7.7e-47 159.3 0.0 9.1e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY97276.1 - 2.6e-14 53.6 0.1 3.5e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY97276.1 - 3e-05 23.6 0.1 4.1e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY97276.1 - 0.00081 18.9 0.2 0.001 18.5 0.2 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY97276.1 - 0.0035 16.5 0.1 0.0044 16.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 ORY97276.1 - 0.035 13.5 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GST_N_3 PF13417.6 ORY97277.1 - 3.2e-15 56.3 0.0 6.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY97277.1 - 1.4e-10 41.3 0.1 2.6e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY97277.1 - 5.9e-06 26.2 0.2 1.2e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY97277.1 - 5.1e-05 23.5 0.1 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY97277.1 - 0.0023 18.1 0.1 0.005 17.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY97277.1 - 0.16 12.2 0.4 0.65 10.2 0.1 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NAP PF00956.18 ORY97278.1 - 5.6e-95 317.6 11.9 5.6e-95 317.6 11.9 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Senescence PF06911.12 ORY97278.1 - 0.057 13.7 0.2 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Senescence-associated protein Cwf_Cwc_15 PF04889.12 ORY97278.1 - 0.27 10.9 24.0 0.12 12.1 12.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 ORY97278.1 - 2 8.6 34.6 0.77 10.0 18.6 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DBR1 PF05011.13 ORY97279.1 - 1.8e-28 99.7 0.2 2.9e-28 99.0 0.2 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 ORY97279.1 - 7.7e-09 36.3 0.1 1.1e-08 35.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY97279.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NUDIX PF00293.28 ORY97280.1 - 1.3e-30 106.1 0.0 1.9e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Band_3_cyto PF07565.13 ORY97281.1 - 1.1 9.0 4.8 0.5 10.1 1.0 1.9 2 0 0 2 2 2 0 Band 3 cytoplasmic domain IMUP PF15761.5 ORY97281.1 - 4.7 8.0 17.8 2.8 8.7 4.6 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Acetyltransf_3 PF13302.7 ORY97282.1 - 5.7e-24 85.4 0.1 2.4e-23 83.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY97282.1 - 0.0039 16.9 0.2 0.55 9.9 0.5 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF1682 PF07946.14 ORY97283.1 - 0.037 13.3 3.5 0.047 12.9 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RRM_1 PF00076.22 ORY97283.1 - 0.18 11.6 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_2 PF13646.6 ORY97285.1 - 1.7e-08 34.7 9.7 0.055 13.9 0.0 6.9 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.22 ORY97285.1 - 4.5e-06 26.5 17.7 2.2 8.8 0.2 8.5 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.20 ORY97285.1 - 6.7e-05 21.6 2.7 0.01 14.4 0.0 4.0 4 1 0 4 4 4 1 Adaptin N terminal region Arm PF00514.23 ORY97285.1 - 0.00021 21.2 0.3 0.006 16.6 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 ORY97285.1 - 0.0016 17.6 7.8 0.011 14.9 1.6 4.0 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 ORY97285.1 - 0.13 12.8 18.8 3.5 8.2 0.0 6.9 6 2 3 9 9 9 0 HEAT-like repeat V-ATPase_H_N PF03224.14 ORY97285.1 - 1.3 8.2 7.2 0.72 9.1 0.4 3.6 4 0 0 4 4 4 0 V-ATPase subunit H Clathrin_lg_ch PF01086.17 ORY97286.1 - 3.9e-48 164.5 16.9 4.4e-48 164.3 16.9 1.0 1 0 0 1 1 1 1 Clathrin light chain Spore_YhcN_YlaJ PF09580.10 ORY97286.1 - 0.1 12.7 3.9 0.15 12.1 4.0 1.4 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Selenoprotein_S PF06936.11 ORY97286.1 - 2.5 7.8 13.2 3.6 7.3 13.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4407 PF14362.6 ORY97286.1 - 3.8 6.8 7.7 2.8 7.2 6.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_16 PF10294.9 ORY97287.1 - 6.2e-26 91.2 0.0 9.5e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Fimbrillin_C PF15495.6 ORY97287.1 - 0.0035 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal PhaG_MnhG_YufB PF03334.14 ORY97287.1 - 0.08 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Na+/H+ antiporter subunit DUF533 PF04391.12 ORY97288.1 - 0.02 14.5 6.0 0.025 14.1 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) RskA PF10099.9 ORY97288.1 - 0.022 15.0 0.8 0.029 14.7 0.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DnaJ-X PF14308.6 ORY97288.1 - 0.031 13.7 2.7 0.042 13.3 2.7 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing Band_3_cyto PF07565.13 ORY97288.1 - 0.032 14.0 2.0 0.034 14.0 2.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF637 PF04830.13 ORY97288.1 - 0.09 12.6 0.4 0.12 12.2 0.4 1.1 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) DUF2076 PF09849.9 ORY97288.1 - 0.22 11.6 16.2 0.31 11.0 16.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Rrn6 PF10214.9 ORY97288.1 - 0.87 8.0 6.8 0.94 7.9 6.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ABA_WDS PF02496.16 ORY97288.1 - 1.8 9.1 10.2 0.12 12.9 5.4 1.5 2 0 0 2 2 2 0 ABA/WDS induced protein DUF4834 PF16118.5 ORY97288.1 - 4.5 8.3 6.1 6.3 7.8 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-C2H2 PF00096.26 ORY97289.1 - 5.6e-15 54.9 5.4 2.4e-07 30.8 0.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY97289.1 - 2.7e-10 40.2 15.0 4.6e-07 30.0 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY97289.1 - 6.6e-10 39.0 5.4 0.00016 22.2 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY97289.1 - 8.5e-06 26.0 0.7 1.1e-05 25.6 0.7 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORY97289.1 - 2.8e-05 24.0 1.2 0.0035 17.3 0.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY97289.1 - 3.2e-05 23.6 3.0 0.0026 17.5 0.1 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORY97289.1 - 5.8e-05 22.9 2.1 0.0066 16.3 0.3 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 ORY97289.1 - 7.7e-05 22.5 2.0 0.011 15.6 0.2 2.2 1 1 1 2 2 2 2 SprT-like zinc ribbon domain zf-met PF12874.7 ORY97289.1 - 0.00017 21.9 0.4 0.022 15.2 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF3268 PF11672.8 ORY97289.1 - 0.00058 20.2 0.1 0.00062 20.1 0.1 1.0 1 0 0 1 1 1 1 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 ORY97289.1 - 0.001 19.3 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 ORY97289.1 - 0.01 15.9 1.3 0.42 10.8 0.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 ORY97289.1 - 0.016 15.3 2.1 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 BED zinc finger Ogr_Delta PF04606.12 ORY97289.1 - 0.018 15.0 0.3 0.028 14.4 0.3 1.4 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger zf_UBZ PF18439.1 ORY97289.1 - 0.026 14.1 0.8 1.5 8.5 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 ORY97289.1 - 0.064 13.3 0.4 2.8 8.0 0.0 2.0 1 1 1 2 2 2 0 CpXC protein zf-H2C2_5 PF13909.6 ORY97289.1 - 0.072 12.9 1.0 0.072 12.9 1.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-DNA_Pol PF08996.10 ORY97289.1 - 0.076 12.8 0.1 0.076 12.8 0.1 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-LYAR PF08790.11 ORY97289.1 - 0.082 12.8 0.1 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger ADK_lid PF05191.14 ORY97289.1 - 0.098 12.7 2.2 7.4 6.6 1.0 2.3 1 1 1 2 2 2 0 Adenylate kinase, active site lid ARS2 PF04959.13 ORY97289.1 - 0.15 12.4 0.4 0.51 10.7 0.1 1.7 1 1 1 2 2 2 0 Arsenite-resistance protein 2 Zn_Tnp_IS1595 PF12760.7 ORY97289.1 - 0.4 10.7 4.0 1.9 8.5 3.8 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain PDZ_1 PF12812.7 ORY97290.1 - 2.7e-35 120.2 0.0 2.2e-24 85.3 0.0 3.2 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 ORY97290.1 - 1.2e-22 81.5 0.0 3.7e-19 70.1 0.0 2.8 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 ORY97290.1 - 7e-21 73.8 0.1 3.3e-06 26.9 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 ORY97290.1 - 3.3e-16 59.4 0.1 1.4e-05 25.3 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORY97290.1 - 9.3e-14 51.6 0.0 0.0034 17.7 0.0 3.8 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 ORY97290.1 - 0.00012 22.0 1.0 0.98 9.4 0.0 3.9 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.26 ORY97290.1 - 0.0012 18.7 0.0 0.0057 16.5 0.0 2.1 3 0 0 3 3 3 1 Trypsin PDZ_3 PF17815.1 ORY97290.1 - 0.023 14.5 0.1 11 5.8 0.0 3.6 4 0 0 4 4 4 0 PDZ domain Peptidase_S46 PF10459.9 ORY97290.1 - 0.092 11.4 0.6 0.23 10.1 0.1 1.7 2 0 0 2 2 2 0 Peptidase S46 Pkinase PF00069.25 ORY97291.1 - 2.4e-71 240.2 0.0 3.9e-71 239.5 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97291.1 - 5.4e-40 137.3 0.0 6.9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY97291.1 - 4.8e-08 33.2 1.5 0.0015 18.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY97291.1 - 8.4e-05 22.0 0.3 0.00013 21.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY97291.1 - 0.0027 16.7 0.1 0.0039 16.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 ORY97291.1 - 0.034 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RhoGAP PF00620.27 ORY97293.1 - 1.3e-49 167.9 0.0 3.2e-49 166.6 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY97293.1 - 2.9e-15 56.2 23.4 2.5e-09 37.2 7.1 3.4 3 0 0 3 3 2 2 LIM domain C1_1 PF00130.22 ORY97293.1 - 6.8e-08 32.3 12.0 6.8e-08 32.3 12.0 4.6 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) NPV_P10 PF05531.12 ORY97293.1 - 0.026 15.0 2.9 7 7.2 0.0 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein GIT1_C PF12205.8 ORY97293.1 - 0.065 13.3 0.2 0.32 11.1 0.2 2.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Filament PF00038.21 ORY97293.1 - 0.096 12.2 15.6 0.31 10.6 2.2 2.8 2 1 1 3 3 3 0 Intermediate filament protein BRE1 PF08647.11 ORY97293.1 - 0.21 11.7 15.0 0.39 10.8 2.6 3.7 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase EMP24_GP25L PF01105.24 ORY97293.1 - 0.35 10.8 2.9 1.4 8.8 0.4 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Prefoldin_2 PF01920.20 ORY97293.1 - 1.5 8.8 6.7 7.2 6.6 0.4 3.4 3 0 0 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.8 ORY97293.1 - 3 7.9 9.4 17 5.5 0.2 3.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 ORY97293.1 - 3.3 7.9 12.2 0.43 10.8 0.9 3.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TLD PF07534.16 ORY97294.1 - 3.8e-21 75.8 0.0 9.2e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 TLD Rav1p_C PF12234.8 ORY97295.1 - 4.8e-175 583.6 1.0 7.4e-175 583.0 1.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 ORY97295.1 - 2.6e-10 40.7 9.7 0.0016 19.2 0.1 7.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY97295.1 - 0.0024 18.1 0.0 0.45 10.8 0.0 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Mur_ligase_M PF08245.12 ORY97296.1 - 1.5e-09 38.1 0.0 5e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ORY97296.1 - 0.00017 21.8 0.0 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain G6PD_C PF02781.16 ORY97297.1 - 4.9e-112 373.9 0.0 6.6e-112 373.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORY97297.1 - 1e-39 137.0 0.2 4.7e-39 134.8 0.1 2.0 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain p450 PF00067.22 ORY97299.1 - 3.4e-81 273.3 0.1 4.2e-81 273.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.21 ORY97300.1 - 1.8e-17 63.4 0.3 2.8e-17 62.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PCSK9_C2 PF18464.1 ORY97300.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Pkinase PF00069.25 ORY97301.1 - 1.3e-40 139.5 0.0 4.3e-40 137.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97301.1 - 2.8e-15 56.3 0.3 1.6e-14 53.8 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY97301.1 - 0.023 13.5 0.1 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 ORY97301.1 - 0.21 11.2 0.5 0.58 9.7 0.2 1.8 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.32 ORY97302.1 - 6.5e-29 99.6 13.4 3.3e-06 27.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY97302.1 - 0.00019 21.6 0.8 0.082 13.2 0.1 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain BORCS6 PF10157.9 ORY97303.1 - 6.5e-13 49.2 1.3 7e-13 49.1 1.3 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Sec34 PF04136.15 ORY97303.1 - 0.00057 19.8 2.0 0.0055 16.6 1.5 2.0 1 1 1 2 2 2 1 Sec34-like family Arfaptin PF06456.13 ORY97303.1 - 0.0089 15.6 2.0 0.033 13.8 0.3 1.9 1 1 1 2 2 2 1 Arfaptin-like domain Spc7 PF08317.11 ORY97303.1 - 0.009 14.9 3.5 0.011 14.7 3.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein TMPIT PF07851.13 ORY97303.1 - 0.017 14.4 1.3 0.02 14.2 1.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 ORY97303.1 - 0.051 13.6 2.9 0.099 12.7 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CK2S PF15011.6 ORY97303.1 - 0.086 12.7 4.2 0.1 12.5 4.2 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate Syntaxin_2 PF14523.6 ORY97303.1 - 0.091 13.1 2.5 0.17 12.3 2.5 1.5 1 1 0 1 1 1 0 Syntaxin-like protein DUF948 PF06103.11 ORY97303.1 - 0.12 12.7 4.5 1.5 9.1 2.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Gly-rich_Ago1 PF12764.7 ORY97303.1 - 0.14 12.9 0.6 0.2 12.5 0.6 1.3 1 0 0 1 1 1 0 Glycine-rich region of argonaut DivIVA PF05103.13 ORY97303.1 - 0.22 11.6 2.8 0.27 11.3 2.8 1.2 1 0 0 1 1 1 0 DivIVA protein BLOC1_2 PF10046.9 ORY97303.1 - 0.3 11.4 5.1 0.5 10.7 1.4 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Duo1 PF08651.10 ORY97303.1 - 1.8 8.4 6.2 3.8 7.3 0.4 2.6 2 1 0 2 2 2 0 DASH complex subunit Duo1 TRAM_LAG1_CLN8 PF03798.16 ORY97304.1 - 6.5e-38 130.5 22.2 6.5e-38 130.5 22.2 1.4 2 0 0 2 2 2 1 TLC domain Methyltransf_25 PF13649.6 ORY97305.1 - 1e-18 67.8 0.0 5e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY97305.1 - 3.8e-18 65.9 0.0 1.4e-17 64.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY97305.1 - 2.3e-13 50.3 0.2 8.7e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY97305.1 - 2.2e-11 43.8 0.0 6.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY97305.1 - 2e-07 30.6 0.0 7.2e-07 28.8 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY97305.1 - 4.9e-07 30.4 0.0 2.2e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY97305.1 - 5e-05 22.7 0.0 8.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ORY97305.1 - 0.00011 21.7 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase TPMT PF05724.11 ORY97305.1 - 0.057 13.1 0.1 0.76 9.4 0.0 2.6 1 1 1 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 ORY97305.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase TPX2 PF06886.11 ORY97305.1 - 1.1 9.5 7.2 3.8 7.8 2.9 2.6 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) zf-C2H2 PF00096.26 ORY97306.1 - 1.1e-06 28.8 15.8 0.00014 22.1 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY97306.1 - 0.00028 21.5 15.7 0.0008 20.0 1.5 2.7 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY97306.1 - 0.0024 17.6 3.9 0.0024 17.6 3.9 2.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 ORY97306.1 - 0.0061 16.9 12.9 0.023 15.1 1.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY97306.1 - 0.011 16.0 8.3 0.52 10.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.7 ORY97306.1 - 0.019 14.9 2.7 0.035 14.1 2.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 ORY97306.1 - 0.024 14.8 2.2 4.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF4574 PF15141.6 ORY97306.1 - 0.028 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 zf-met PF12874.7 ORY97306.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 ORY97306.1 - 0.16 12.0 14.1 0.21 11.6 2.7 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 ORY97306.1 - 0.28 11.9 6.1 0.49 11.1 6.1 1.5 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-Sec23_Sec24 PF04810.15 ORY97306.1 - 0.78 9.8 4.6 12 6.1 4.7 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 ORY97306.1 - 2.8 8.3 10.4 13 6.2 0.8 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PI3_PI4_kinase PF00454.27 ORY97307.1 - 5.1e-46 157.5 0.0 9.7e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase bZIP_1 PF00170.21 ORY97307.1 - 0.077 13.1 2.7 0.22 11.6 2.7 1.8 1 0 0 1 1 1 0 bZIP transcription factor PH_RBD PF12068.8 ORY97307.1 - 0.12 11.8 0.6 0.27 10.7 0.1 1.8 2 0 0 2 2 2 0 Rab-binding domain (RBD) Asp-B-Hydro_N PF05279.11 ORY97308.1 - 1.2 9.2 9.2 1.7 8.7 9.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region p450 PF00067.22 ORY97309.1 - 1e-78 265.2 0.1 5e-78 262.9 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF22 PF01629.16 ORY97311.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF22 Ribosomal_S17e PF00833.18 ORY97312.1 - 8.6e-57 190.3 0.4 1e-56 190.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 Glyco_hydro_18 PF00704.28 ORY97313.1 - 5.3e-15 55.9 0.0 5.2e-14 52.7 0.0 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF2967 PF11179.8 ORY97313.1 - 0.52 8.4 12.1 0.66 8.0 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) GATA PF00320.27 ORY97315.1 - 2.1e-16 59.2 5.1 4.2e-16 58.3 5.1 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY97315.1 - 3.2e-05 23.3 5.6 0.00039 19.9 0.1 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Elf1 PF05129.13 ORY97315.1 - 0.0057 16.7 0.1 0.0057 16.7 0.1 1.9 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.10 ORY97315.1 - 0.041 13.6 0.7 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Auto_anti-p27 PF06677.12 ORY97315.1 - 0.049 13.8 0.7 0.079 13.1 0.7 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 ORY97315.1 - 0.16 12.1 0.5 0.31 11.2 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain RrnaAD PF00398.20 ORY97316.1 - 8.8e-50 169.2 0.0 9.9e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ORY97316.1 - 0.00071 20.2 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MinC_N PF05209.13 ORY97316.1 - 0.0017 18.3 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 Septum formation inhibitor MinC, N-terminal domain Methyltransf_11 PF08241.12 ORY97316.1 - 0.018 15.6 0.0 0.048 14.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain BRO1 PF03097.18 ORY97317.1 - 8.2e-22 77.5 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 ORY97317.1 - 1.6e-05 24.1 0.3 0.00071 18.7 0.5 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5355) adh_short_C2 PF13561.6 ORY97318.1 - 1.6e-55 188.2 0.8 1.8e-55 188.1 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY97318.1 - 2.3e-43 147.9 0.4 2.8e-43 147.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY97318.1 - 1.3e-11 44.7 0.1 1.7e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY97318.1 - 0.00026 20.2 0.1 0.00039 19.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Apt1 PF10351.9 ORY97319.1 - 0.00068 18.6 0.1 0.00086 18.3 0.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain NPR3 PF03666.13 ORY97319.1 - 0.6 8.8 3.8 4.1 6.1 3.9 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF936 PF06075.12 ORY97319.1 - 2.9 6.7 10.5 3.7 6.4 10.5 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Secretin_N_2 PF07655.13 ORY97319.1 - 5.5 7.6 16.4 8.5 7.0 16.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain STE PF02200.16 ORY97320.1 - 0.0012 19.2 0.1 0.0023 18.3 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor Y_phosphatase PF00102.27 ORY97322.1 - 3e-71 239.7 1.1 8.5e-71 238.2 0.3 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 ORY97322.1 - 2.8e-14 53.5 0.1 5e-12 46.3 0.0 3.5 4 1 1 5 5 5 1 Rhodanese-like domain Gastrin PF00918.17 ORY97322.1 - 0.11 13.5 0.1 0.46 11.5 0.1 2.1 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Y_phosphatase3 PF13350.6 ORY97322.1 - 0.16 11.9 0.3 0.42 10.5 0.1 1.8 2 1 0 2 2 2 0 Tyrosine phosphatase family UQ_con PF00179.26 ORY97323.1 - 4.5e-48 162.5 0.0 5.1e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY97323.1 - 0.00039 20.1 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY97323.1 - 0.012 15.4 0.1 0.025 14.4 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 ORY97323.1 - 0.15 12.4 0.2 0.19 12.0 0.2 1.4 1 1 0 1 1 1 0 RWD domain RNA_POL_M_15KD PF02150.16 ORY97324.1 - 8.6e-16 57.5 10.2 6.9e-14 51.4 5.7 2.5 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 ORY97324.1 - 1.2e-12 47.4 11.5 1.7e-12 46.9 1.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) CpXC PF14353.6 ORY97324.1 - 0.0023 18.0 1.9 0.25 11.4 0.2 2.2 2 0 0 2 2 2 2 CpXC protein UPF0547 PF10571.9 ORY97324.1 - 0.0071 16.4 7.1 0.33 11.1 0.1 3.3 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 DZR PF12773.7 ORY97324.1 - 0.0072 16.3 8.9 0.079 13.0 2.6 2.5 3 0 0 3 3 3 2 Double zinc ribbon zinc_ribbon_13 PF09855.9 ORY97324.1 - 0.008 16.3 1.6 1.2 9.3 0.1 2.5 2 0 0 2 2 2 1 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) IBR PF01485.21 ORY97324.1 - 0.014 15.6 7.7 0.16 12.3 2.3 2.6 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 ORY97324.1 - 0.035 14.0 7.5 0.23 11.4 1.3 2.4 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Ogr_Delta PF04606.12 ORY97324.1 - 0.051 13.6 0.3 0.051 13.6 0.3 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger C1_1 PF00130.22 ORY97324.1 - 0.057 13.3 2.8 0.13 12.2 1.0 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.7 ORY97324.1 - 0.063 13.3 1.1 0.063 13.3 1.1 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.19 ORY97324.1 - 0.87 9.6 4.1 0.33 11.0 1.1 1.8 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 ORY97324.1 - 2.8 8.4 11.8 0.75 10.2 0.1 3.0 1 1 2 3 3 3 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 ORY97324.1 - 5.9 6.8 14.4 0.94 9.3 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Ras PF00071.22 ORY97325.1 - 5.5e-49 165.9 0.2 6.4e-49 165.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY97325.1 - 2.7e-16 59.9 0.0 4.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY97325.1 - 1.6e-11 44.0 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY97325.1 - 4.7e-08 32.8 0.1 1.5e-07 31.1 0.1 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY97325.1 - 3.5e-07 30.3 0.1 8.6e-05 22.5 0.0 2.1 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY97325.1 - 1.3e-05 24.7 0.1 9.9e-05 21.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORY97325.1 - 0.00019 21.5 0.0 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY97325.1 - 0.00085 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 ORY97325.1 - 0.0035 17.3 0.1 0.0081 16.2 0.1 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_14 PF13173.6 ORY97325.1 - 0.0037 17.3 0.0 0.0094 16.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY97325.1 - 0.024 15.0 0.0 0.028 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 ORY97325.1 - 0.033 13.6 0.0 0.18 11.2 0.0 2.1 2 1 1 3 3 3 0 Bacterial TniB protein MeaB PF03308.16 ORY97325.1 - 0.12 11.3 0.0 4.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Vac7 PF12751.7 ORY97331.1 - 4.3e-11 42.9 13.0 4.6e-09 36.2 13.0 3.0 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 PBP1_TM PF14812.6 ORY97331.1 - 0.04 14.3 3.7 13 6.3 2.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Caskin-Pro-rich PF16907.5 ORY97331.1 - 0.29 11.7 9.1 0.19 12.2 6.5 2.0 2 0 0 2 2 2 0 Proline rich region of Caskin proteins MRC1 PF09444.10 ORY97331.1 - 3.9 8.0 7.6 1.9 9.0 0.6 2.2 2 0 0 2 2 2 0 MRC1-like domain TRM13 PF05206.14 ORY97341.1 - 2e-83 280.0 1.2 2.8e-83 279.5 1.2 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 ORY97341.1 - 5.4e-11 42.1 2.4 8e-11 41.6 0.9 2.2 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 ORY97341.1 - 8.8e-09 35.0 3.7 2.2e-08 33.7 3.7 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-TRAF PF02176.18 ORY97341.1 - 0.099 13.3 2.1 0.13 13.0 0.1 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger adh_short PF00106.25 ORY97343.1 - 7e-15 55.0 0.3 9.2e-15 54.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY97343.1 - 1.7e-11 44.1 0.1 2.8e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY97343.1 - 0.00025 20.6 0.1 0.012 15.1 0.1 2.4 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 ORY97343.1 - 0.0067 16.6 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ORY97343.1 - 0.035 14.0 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ORY97343.1 - 0.039 13.0 0.1 0.055 12.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain LSM PF01423.22 ORY97344.1 - 9.8e-21 73.2 0.2 1.4e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 ORY97344.1 - 0.00017 22.2 3.1 0.00023 21.8 3.1 1.4 1 0 0 1 1 1 1 Glycine rich protein family FoP_duplication PF13865.6 ORY97344.1 - 0.0012 19.3 8.7 0.0021 18.6 8.7 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Ribosomal_L24e PF01246.20 ORY97345.1 - 1e-30 105.8 0.2 1.9e-30 104.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Recombinase PF07508.13 ORY97345.1 - 0.015 15.7 0.4 0.018 15.4 0.4 1.3 1 0 0 1 1 1 0 Recombinase PhoLip_ATPase_C PF16212.5 ORY97346.1 - 8.2e-74 248.5 28.4 8.2e-74 248.5 28.4 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY97346.1 - 4.1e-23 80.9 0.1 1.5e-22 79.0 0.1 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY97346.1 - 2.1e-13 50.2 0.0 8.8e-12 44.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY97346.1 - 2.3e-09 37.9 4.6 0.00011 22.6 4.6 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY97346.1 - 5.7e-05 22.7 4.6 0.00013 21.6 0.0 3.1 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY97346.1 - 0.0017 18.1 0.1 0.0093 15.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 ORY97346.1 - 3.5 7.8 9.2 0.22 11.6 2.8 2.4 2 0 0 2 2 2 0 C-terminus of AA_permease Lactamase_B_6 PF16661.5 ORY97347.1 - 1.4e-66 223.7 0.0 2.3e-66 222.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 ORY97347.1 - 5.4e-34 117.8 1.5 7.1e-28 97.9 0.0 2.8 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 ORY97347.1 - 4.2e-17 62.4 0.1 1.5e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 ORY97347.1 - 4.3e-13 49.0 0.0 8.9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORY97347.1 - 2.5e-08 33.7 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY97347.1 - 2.1e-06 27.9 0.0 4.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RasGEF PF00617.19 ORY97348.1 - 9.7e-48 162.7 0.2 2.1e-47 161.6 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY97348.1 - 2.3e-13 50.3 5.2 4.2e-13 49.4 3.2 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF2464 PF10240.9 ORY97348.1 - 0.16 11.5 0.7 0.4 10.2 0.7 1.7 1 0 0 1 1 1 0 Multivesicular body subunit 12 CHCH PF06747.13 ORY97349.1 - 9.7e-06 25.6 6.8 1.2e-05 25.3 6.8 1.1 1 0 0 1 1 1 1 CHCH domain cNMPbd_u2 PF16643.5 ORY97350.1 - 0.027 14.9 0.1 0.035 14.6 0.1 1.1 1 0 0 1 1 1 0 Unstructured region on cNMP-binding protein XAF1_C PF18608.1 ORY97350.1 - 0.36 10.4 2.5 0.45 10.1 0.3 2.0 1 1 1 2 2 2 0 XIAP-associated factor 1 C-terminal domain Ribosomal_S8 PF00410.19 ORY97351.1 - 2.5e-23 82.4 0.0 3.6e-23 81.9 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein S8 LAGLIDADG_WhiA PF14527.6 ORY97351.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain RdRP PF05183.12 ORY97352.1 - 1.2e-186 621.9 0.1 1.8e-186 621.3 0.1 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RNA_pol_3_Rpc31 PF11705.8 ORY97352.1 - 0.00033 21.0 4.6 0.00062 20.1 4.6 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RRM_1 PF00076.22 ORY97352.1 - 0.00073 19.3 0.0 0.0033 17.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myc_N PF01056.18 ORY97352.1 - 0.019 14.9 1.4 0.035 14.0 1.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.12 ORY97352.1 - 0.075 12.0 2.6 0.12 11.3 2.6 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein HHH_4 PF14490.6 ORY97352.1 - 0.15 12.1 0.0 0.84 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain Nop14 PF04147.12 ORY97352.1 - 0.18 10.0 5.5 0.27 9.4 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.6 ORY97352.1 - 0.18 12.0 7.6 0.43 10.8 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 ORY97352.1 - 0.38 10.8 4.4 0.81 9.7 4.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 ORY97352.1 - 0.85 8.7 14.0 1.5 7.9 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 ORY97352.1 - 1.8 8.2 5.3 4.1 7.1 5.3 1.5 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 ORY97352.1 - 2.7 6.0 4.6 4.6 5.2 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 ORY97352.1 - 4.9 6.4 12.5 8.8 5.6 12.5 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 ORY97352.1 - 6.3 6.5 11.0 12 5.5 11.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 ORY97352.1 - 6.6 5.8 9.4 14 4.7 9.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein adh_short PF00106.25 ORY97353.1 - 6.5e-45 153.0 1.0 8.6e-45 152.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY97353.1 - 7.8e-31 107.4 0.5 1e-30 107.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY97353.1 - 6.9e-06 26.1 0.4 1e-05 25.6 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY97353.1 - 0.00017 21.1 0.1 0.00035 20.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY97353.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family TauD PF02668.16 ORY97354.1 - 1.8e-26 93.6 0.0 2.5e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ORY97354.1 - 7.2e-05 22.0 0.1 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 CsiD UvdE PF03851.14 ORY97354.1 - 0.046 13.0 0.0 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 UV-endonuclease UvdE Suc_Fer-like PF06999.12 ORY97355.1 - 6.7e-62 208.8 0.0 7.8e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-MIZ PF02891.20 ORY97357.1 - 3.3e-08 33.2 1.8 6.1e-08 32.3 1.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zinc_ribbon_2 PF13240.6 ORY97357.1 - 0.069 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf_CopZ PF18423.1 ORY97357.1 - 0.069 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Zinc binding domain zf-LITAF-like PF10601.9 ORY97357.1 - 0.089 13.1 1.3 0.2 11.9 1.3 1.6 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain GATA PF00320.27 ORY97358.1 - 4.4e-29 99.8 25.5 2.1e-15 56.0 5.6 3.1 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY97358.1 - 2.2e-07 30.3 6.1 0.00092 18.7 0.5 2.8 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY97358.1 - 6.6e-05 22.9 1.3 0.35 11.0 0.2 2.9 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORY97358.1 - 0.0015 18.6 8.9 0.15 12.3 0.5 3.0 2 1 1 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TDP43_N PF18694.1 ORY97358.1 - 0.029 14.2 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain zf-RRN7 PF11781.8 ORY97358.1 - 0.21 11.3 8.1 0.45 10.2 0.4 2.7 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Endostatin PF06482.11 ORY97358.1 - 0.31 10.5 9.8 28 4.1 0.0 2.5 1 1 1 2 2 2 0 Collagenase NC10 and Endostatin eIF-5_eIF-2B PF01873.17 ORY97358.1 - 0.68 9.8 7.8 1.4 8.8 0.8 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 ORY97358.1 - 1.2 9.1 15.4 0.69 9.9 1.3 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-RRPl_C4 PF17026.5 ORY97358.1 - 6.7 6.9 9.0 39 4.4 0.8 2.9 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type TPR_1 PF00515.28 ORY97359.1 - 9.5e-48 158.2 38.2 2.5e-08 33.4 0.1 11.4 10 2 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97359.1 - 2e-40 133.7 33.3 8.8e-06 25.4 0.0 10.7 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 ORY97359.1 - 1.4e-27 93.5 30.9 2.9e-05 23.9 2.2 10.9 9 2 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 ORY97359.1 - 2.1e-27 93.5 29.4 0.00031 20.9 0.1 9.5 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORY97359.1 - 3.5e-25 88.3 16.7 4.1e-05 24.0 0.2 6.8 3 2 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97359.1 - 4.3e-23 81.4 27.3 1.5e-05 25.2 3.0 6.4 4 4 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97359.1 - 3e-22 77.4 15.2 0.0052 17.5 0.1 8.2 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 ORY97359.1 - 6.8e-22 76.9 36.7 3.7e-06 26.5 1.4 9.4 6 3 3 9 9 9 5 TPR repeat TPR_16 PF13432.6 ORY97359.1 - 1.1e-21 77.2 14.8 8.3e-07 29.6 0.9 6.5 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY97359.1 - 4.1e-18 64.0 22.0 0.015 15.3 0.5 9.3 8 2 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 ORY97359.1 - 3.8e-15 55.8 11.7 0.00013 22.0 0.4 6.5 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 ORY97359.1 - 5.6e-15 54.9 27.9 0.012 16.2 2.2 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY97359.1 - 1.2e-11 44.7 17.3 2e-06 28.0 5.5 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 ORY97359.1 - 2.8e-07 30.3 21.0 0.0014 18.1 7.3 3.7 2 2 0 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 ORY97359.1 - 3.1e-07 29.9 16.1 0.079 12.2 1.0 4.8 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY97359.1 - 8.4e-05 22.3 19.7 0.091 12.7 0.1 7.2 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY97359.1 - 0.00011 22.4 2.9 1.8 8.9 0.1 5.5 4 3 2 6 6 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 ORY97359.1 - 0.00046 20.0 10.9 0.17 11.6 4.3 3.3 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 ORY97359.1 - 0.0018 17.3 4.3 0.36 9.8 0.5 3.0 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Tcf25 PF04910.14 ORY97359.1 - 0.0037 16.4 3.1 0.064 12.3 0.0 2.7 2 2 1 3 3 3 1 Transcriptional repressor TCF25 TPR_3 PF07720.12 ORY97359.1 - 0.013 15.5 17.8 1.2 9.2 0.5 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 ORY97359.1 - 0.031 14.7 9.7 3.4 8.1 0.1 3.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TOM20_plant PF06552.12 ORY97359.1 - 0.12 12.1 6.4 15 5.3 0.2 4.7 2 1 3 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 DUF627 PF04781.12 ORY97359.1 - 1.8 8.6 4.3 54 3.9 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF627) MIT PF04212.18 ORY97359.1 - 3 8.0 27.9 8.7 6.5 0.2 6.7 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain DUF5344 PF17279.2 ORY97359.1 - 6.1 7.5 8.4 36 5.0 0.1 4.7 5 0 0 5 5 5 0 Family of unknown function (DUF5344) Coatomer_WDAD PF04053.14 ORY97359.1 - 9.1 5.2 11.7 11 4.9 3.5 3.8 2 1 2 4 4 4 0 Coatomer WD associated region Amidohydro_2 PF04909.14 ORY97360.1 - 2.8e-29 102.8 3.7 7.3e-29 101.5 3.7 1.7 1 1 0 1 1 1 1 Amidohydrolase Peptidase_C1_2 PF03051.15 ORY97362.1 - 6.1e-158 526.2 0.2 6.8e-158 526.0 0.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 ORY97362.1 - 2.1e-06 28.0 0.3 0.0064 16.6 0.3 2.3 2 0 0 2 2 2 2 Papain family cysteine protease B-block_TFIIIC PF04182.12 ORY97363.1 - 8.4e-14 51.5 0.0 1.2e-10 41.4 0.0 3.7 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_micro PF17007.5 ORY97363.1 - 1.8e-07 30.3 1.1 0.018 13.9 0.7 3.3 3 0 0 3 3 3 2 HTH-like MarR PF01047.22 ORY97363.1 - 0.00068 19.5 0.0 0.024 14.6 0.0 2.8 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 ORY97363.1 - 0.0024 17.7 0.4 0.025 14.5 0.1 3.0 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 ORY97363.1 - 0.0031 17.0 4.3 0.019 14.5 0.0 4.2 6 0 0 6 6 6 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 ORY97363.1 - 0.043 14.3 0.1 0.51 10.9 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_29 PF13551.6 ORY97363.1 - 0.059 13.4 0.4 0.7 10.0 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn helix RHH_1 PF01402.21 ORY97363.1 - 0.76 9.8 5.0 7 6.7 0.3 3.2 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Polysacc_deac_1 PF01522.21 ORY97364.1 - 2.4e-12 46.8 0.1 4.4e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase YtxC PF08812.11 ORY97364.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 YtxC-like family HABP4_PAI-RBP1 PF04774.15 ORY97364.1 - 0.055 14.3 5.8 0.1 13.5 5.8 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family PHD PF00628.29 ORY97365.1 - 2.8e-07 30.3 7.2 9.5e-07 28.6 7.2 2.0 1 0 0 1 1 1 1 PHD-finger GATA PF00320.27 ORY97365.1 - 4.7e-05 22.9 4.6 0.00014 21.3 4.6 1.9 1 0 0 1 1 1 1 GATA zinc finger Nucleo_P87 PF07267.11 ORY97365.1 - 0.0096 14.8 1.6 0.014 14.3 1.6 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 zf-HC5HC2H PF13771.6 ORY97365.1 - 0.043 14.1 0.6 0.043 14.1 0.6 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain MRVI1 PF05781.12 ORY97365.1 - 0.064 11.9 0.3 0.1 11.3 0.3 1.3 1 0 0 1 1 1 0 MRVI1 protein zf-HC5HC2H_2 PF13832.6 ORY97365.1 - 0.74 10.0 3.3 0.96 9.6 0.9 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain DUF2373 PF10180.9 ORY97366.1 - 8.1e-22 76.8 1.3 1.4e-21 76.1 1.3 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.18 ORY97366.1 - 0.052 13.6 1.7 0.052 13.6 1.7 1.9 1 1 1 2 2 2 0 NOT2 / NOT3 / NOT5 family DUF775 PF05603.12 ORY97366.1 - 0.19 11.3 2.4 0.21 11.1 0.6 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF775) ANAPC4_WD40 PF12894.7 ORY97367.1 - 1.4e-08 34.9 0.9 0.017 15.4 0.2 5.5 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 ORY97367.1 - 0.0016 18.4 1.0 2.2 8.2 0.0 3.0 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term eIF2A PF08662.11 ORY97367.1 - 0.011 15.7 0.0 0.2 11.5 0.0 2.6 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ORY97367.1 - 0.037 14.9 15.4 2.3 9.2 0.0 5.6 6 0 0 6 6 6 0 WD domain, G-beta repeat Lactonase PF10282.9 ORY97367.1 - 0.12 11.6 0.1 13 4.9 0.0 2.5 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Lactamase_B PF00753.27 ORY97368.1 - 3.5e-20 72.9 0.1 4.8e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 ORY97368.1 - 1.4e-15 57.0 0.0 3.4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 ORY97368.1 - 6.7e-06 25.7 0.0 9.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HTH_32 PF13565.6 ORY97368.1 - 0.12 13.0 0.2 0.44 11.2 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain TPR_1 PF00515.28 ORY97369.1 - 0.00025 20.7 6.6 0.002 17.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY97369.1 - 0.00029 20.5 4.5 0.00061 19.4 0.1 3.4 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 ORY97369.1 - 0.0039 17.3 8.1 0.13 12.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY97369.1 - 0.0047 16.7 1.5 0.08 12.7 0.3 2.2 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.6 ORY97369.1 - 0.028 14.9 16.6 0.94 10.0 0.0 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97369.1 - 0.033 14.5 5.9 1.1 9.5 0.7 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97369.1 - 0.035 14.2 0.1 0.035 14.2 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97369.1 - 0.044 14.6 18.4 2.2 9.3 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY97369.1 - 0.063 13.7 0.1 7.1 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Spexin PF15171.6 ORY97369.1 - 1.2 9.4 5.7 0.7 10.1 0.4 2.8 2 2 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin Las1 PF04031.13 ORY97370.1 - 2.8e-45 154.1 0.6 6.2e-45 153.0 0.3 1.8 2 0 0 2 2 2 1 Las1-like Cob_adeno_trans PF01923.18 ORY97370.1 - 0.013 15.6 0.0 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Adaptin_binding PF10199.9 ORY97370.1 - 0.025 15.2 0.8 2 9.1 0.3 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4451 PF14616.6 ORY97372.1 - 3.1e-20 72.6 5.4 5.6e-20 71.8 5.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) ZapB PF06005.12 ORY97373.1 - 0.018 15.5 0.8 0.11 13.0 0.2 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Tup_N PF08581.10 ORY97373.1 - 0.048 14.0 2.8 0.12 12.7 2.8 1.7 1 0 0 1 1 1 0 Tup N-terminal Bromodomain PF00439.25 ORY97374.1 - 3e-46 155.4 5.8 1.2e-22 79.8 0.3 2.9 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 ORY97374.1 - 7.7e-18 64.4 3.4 2e-16 59.9 3.4 2.6 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation CENP-Q PF13094.6 ORY97374.1 - 0.01 16.0 3.8 0.01 16.0 3.8 1.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.12 ORY97374.1 - 3.7 8.3 6.1 0.63 10.7 0.9 2.5 2 0 0 2 2 2 0 SlyX Strep_SA_rep PF06696.11 ORY97374.1 - 5 7.2 4.9 32 4.7 0.2 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF4685 PF15737.5 ORY97374.1 - 8.5 6.8 11.0 2.1 8.8 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) WD40 PF00400.32 ORY97375.1 - 3.7e-38 128.8 30.5 3.1e-06 27.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY97375.1 - 8e-10 38.9 0.9 0.072 13.4 0.0 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY97375.1 - 6.7e-07 28.3 6.2 0.49 9.0 0.1 5.5 4 2 2 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY97375.1 - 1.9e-06 27.4 0.2 2.1e-05 24.0 0.1 2.8 1 1 1 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 ORY97375.1 - 0.00049 20.1 0.3 17 5.5 0.0 4.9 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 ORY97375.1 - 0.0014 18.3 0.0 0.047 13.3 0.0 2.3 1 1 1 2 2 2 1 PQQ-like domain DUF5046 PF16465.5 ORY97375.1 - 0.016 14.7 0.0 1.7 8.0 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) DUF1513 PF07433.11 ORY97375.1 - 0.022 13.9 0.0 1.6 7.7 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Frtz PF11768.8 ORY97375.1 - 0.024 13.0 0.4 2.5 6.3 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Sedlin_N PF04628.13 ORY97376.1 - 3e-47 160.0 1.8 3.4e-47 159.8 1.8 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ORY97376.1 - 3.3e-09 36.8 0.8 3.7e-09 36.6 0.8 1.3 1 1 0 1 1 1 1 Sybindin-like family mRNA_decap_C PF16741.5 ORY97376.1 - 0.04 13.2 0.2 0.11 11.9 0.2 1.7 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus DUF508 PF04370.12 ORY97376.1 - 0.073 12.8 0.6 0.079 12.7 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF508) CdiA_C_tRNase PF18664.1 ORY97376.1 - 0.32 11.2 2.2 1.5 9.0 0.6 2.2 1 1 1 2 2 2 0 CdiA C-terminal tRNase domain Bromodomain PF00439.25 ORY97377.1 - 2.6e-23 81.9 0.5 5.7e-23 80.8 0.5 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 ORY97377.1 - 7.5e-08 32.6 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY97377.1 - 2.5e-05 24.2 0.0 5.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY97377.1 - 0.00025 21.4 0.1 0.00044 20.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1722 PF08349.11 ORY97377.1 - 0.005 17.1 3.3 2.9 8.2 0.1 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF1722) malic PF00390.19 ORY97377.1 - 0.13 12.0 0.7 0.24 11.2 0.7 1.4 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain HEAT PF02985.22 ORY97378.1 - 5.3e-17 60.5 20.7 0.00076 19.5 0.0 11.4 11 1 1 12 12 12 4 HEAT repeat HEAT_EZ PF13513.6 ORY97378.1 - 3.1e-14 53.1 11.2 5.4e-10 39.6 0.0 8.1 9 1 1 10 10 9 1 HEAT-like repeat IBN_N PF03810.19 ORY97378.1 - 1.4e-11 44.1 0.3 2.9e-10 39.9 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 ORY97378.1 - 3.4e-10 40.2 7.4 0.0056 17.1 0.0 7.5 5 2 4 9 9 9 4 HEAT repeats Arm PF00514.23 ORY97378.1 - 5.9e-05 23.0 5.2 0.05 13.7 0.0 6.4 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 ORY97378.1 - 0.004 16.9 0.1 4.1 7.2 0.0 3.7 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) RIX1 PF08167.12 ORY97378.1 - 0.0046 16.7 0.2 1.5 8.5 0.0 4.2 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 ORY97378.1 - 0.0088 15.6 2.3 3 7.3 0.1 4.6 5 1 0 5 5 5 1 CLASP N terminal DUF3385 PF11865.8 ORY97378.1 - 0.0089 15.9 2.1 26 4.7 0.1 5.2 4 2 1 5 5 5 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 ORY97378.1 - 0.012 14.8 0.3 19 4.2 0.0 3.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DRIM PF07539.12 ORY97378.1 - 0.061 11.6 6.4 3.7 5.7 0.1 4.9 3 3 2 6 6 6 0 Down-regulated in metastasis GATA PF00320.27 ORY97379.1 - 2.5e-17 62.2 3.1 4.6e-17 61.3 3.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 ORY97379.1 - 1.8e-12 46.9 1.7 1.8e-12 46.9 1.7 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 ORY97379.1 - 0.22 11.0 0.6 0.41 10.2 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.7 ORY97379.1 - 0.23 11.5 1.0 1.2 9.2 1.3 1.9 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY97379.1 - 4.2 7.2 4.5 19 5.1 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain PAT1 PF09770.9 ORY97379.1 - 4.8 5.3 20.8 8.9 4.4 20.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TRAM_LAG1_CLN8 PF03798.16 ORY97380.1 - 0.0006 19.6 19.8 0.00078 19.2 19.0 1.6 1 1 0 1 1 1 1 TLC domain His_Phos_1 PF00300.22 ORY97381.1 - 1.2e-20 74.0 0.0 1.4e-14 54.3 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 ORY97381.1 - 0.0002 20.8 0.2 0.00077 18.9 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 ORY97382.1 - 5.6e-49 166.9 0.0 2.3e-48 164.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97382.1 - 1.6e-28 99.7 0.0 2.4e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97382.1 - 5.9e-05 22.5 0.3 0.00011 21.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 ORY97382.1 - 0.00056 19.0 0.0 0.00083 18.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY97382.1 - 0.0011 19.0 5.3 0.0011 18.9 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family SUIM_assoc PF16619.5 ORY97382.1 - 0.0074 16.3 7.7 0.022 14.8 7.7 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 ORY97382.1 - 0.021 14.4 11.7 0.031 13.9 11.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kdo PF06293.14 ORY97382.1 - 0.042 13.2 0.2 0.095 12.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spt20 PF12090.8 ORY97382.1 - 0.33 10.5 7.9 0.46 10.0 7.9 1.1 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 ORY97382.1 - 3 7.3 8.1 4.8 6.6 8.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sugar_tr PF00083.24 ORY97383.1 - 4.8e-103 345.5 23.6 1.1e-51 176.2 9.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY97383.1 - 3.9e-24 85.2 30.8 4.4e-23 81.8 20.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3054 PF11255.8 ORY97383.1 - 0.84 10.2 16.6 0.13 12.8 11.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Pkinase PF00069.25 ORY97384.1 - 2.7e-74 249.9 0.0 3.3e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97384.1 - 2.5e-38 131.9 0.0 3.3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97384.1 - 1e-07 31.6 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY97384.1 - 0.064 12.2 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY97384.1 - 0.15 11.9 0.0 0.5 10.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SF3b10 PF07189.11 ORY97385.1 - 8.2e-41 138.0 0.2 9.1e-41 137.9 0.2 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.9 ORY97385.1 - 0.043 12.9 0.1 0.047 12.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) DUF4598 PF15370.6 ORY97386.1 - 3.5e-23 82.2 6.2 3.5e-23 82.2 6.2 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) RNase_PH PF01138.21 ORY97387.1 - 5.7e-23 81.9 0.0 8.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY97387.1 - 6.8e-14 51.7 0.0 1.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 2-oxoacid_dh PF00198.23 ORY97388.1 - 3.9e-75 252.3 0.0 5.6e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY97388.1 - 3.2e-17 62.1 0.0 6.2e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY97388.1 - 1.9e-15 56.9 1.1 2.6e-15 56.5 0.1 1.9 2 0 0 2 2 2 1 e3 binding domain F-box-like PF12937.7 ORY97389.1 - 1.5e-05 24.8 1.2 2.7e-05 24.0 0.3 2.0 2 0 0 2 2 2 1 F-box-like TPR_2 PF07719.17 ORY97389.1 - 0.0053 16.8 0.5 0.041 14.0 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97389.1 - 0.012 15.5 0.1 0.045 13.6 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box PF00646.33 ORY97389.1 - 0.016 15.1 0.7 0.094 12.6 0.1 2.6 3 0 0 3 3 3 0 F-box domain TPR_2 PF07719.17 ORY97390.1 - 5.4e-05 23.0 1.5 0.0067 16.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97390.1 - 0.00071 19.3 0.1 0.02 14.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY97390.1 - 0.016 15.7 0.1 0.051 14.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY97390.1 - 0.021 15.4 2.1 0.058 14.1 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97390.1 - 0.049 13.9 3.5 0.14 12.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY97390.1 - 0.1 12.5 0.3 0.33 10.9 0.3 1.9 1 0 0 1 1 1 0 F-box-like Glyco_hyd_65N_2 PF14498.6 ORY97390.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TPR_9 PF13371.6 ORY97391.1 - 2.4e-05 24.4 0.1 0.00011 22.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY97391.1 - 0.00011 22.8 0.1 0.00011 22.8 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97391.1 - 0.0041 17.1 1.4 0.007 16.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box PF00646.33 ORY97391.1 - 0.014 15.3 1.8 0.034 14.0 1.1 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 ORY97391.1 - 0.023 14.6 0.4 0.07 13.0 0.4 1.9 1 0 0 1 1 1 0 F-box-like TPR_14 PF13428.6 ORY97391.1 - 0.059 14.2 1.1 0.7 10.9 0.2 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY97391.1 - 0.15 12.7 0.1 5.7 7.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_3 PF00933.21 ORY97392.1 - 5.8e-65 219.8 0.1 7.6e-65 219.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ORY97392.1 - 1.6e-43 149.0 0.0 2.9e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ORY97392.1 - 6.6e-12 45.4 0.0 5.6e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain CAF1 PF04857.20 ORY97393.1 - 6.3e-85 285.1 1.5 6.3e-85 285.1 1.5 2.1 2 0 0 2 2 2 1 CAF1 family ribonuclease CDC45 PF02724.14 ORY97393.1 - 0.46 8.7 10.6 0.88 7.8 10.6 1.4 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 ORY97393.1 - 0.73 10.2 3.7 1.8 9.0 3.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 GCP5-Mod21 PF14609.6 ORY97393.1 - 4.7 5.4 17.5 0.23 9.8 11.2 1.8 2 0 0 2 2 2 0 gamma-Tubulin ring complex non-core subunit mod21 Presenilin PF01080.17 ORY97393.1 - 5.5 5.6 6.0 9 4.9 6.0 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 ORY97393.1 - 7.1 4.6 19.3 13 3.7 19.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi DLH PF01738.18 ORY97394.1 - 3.1e-30 105.4 0.0 4.1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 ORY97394.1 - 0.065 12.9 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PBD PF00786.28 ORY97396.1 - 1.5e-05 25.2 0.0 4.9e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain WRNPLPNID PF15017.6 ORY97396.1 - 0.35 11.8 5.1 1.3 9.9 3.7 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box TRIC PF05197.13 ORY97397.1 - 1.6e-07 31.1 0.5 2.5e-07 30.5 0.5 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 ORY97397.1 - 9.8 6.1 8.8 0.23 11.4 0.4 2.5 3 0 0 3 3 3 0 UPF0126 domain OCD_Mu_crystall PF02423.15 ORY97398.1 - 3.4e-46 157.7 2.5 3.8e-46 157.5 2.5 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ORY97398.1 - 9.1e-11 42.0 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ORY97398.1 - 0.00017 22.1 0.0 0.0013 19.3 0.0 2.4 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ORY97398.1 - 0.0007 19.9 0.0 0.0017 18.6 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 ORY97398.1 - 0.0081 15.7 0.3 0.02 14.4 0.1 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus GFO_IDH_MocA PF01408.22 ORY97398.1 - 0.068 14.0 0.0 0.2 12.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ALMT PF11744.8 ORY97399.1 - 2.9e-20 72.6 5.8 2.9e-20 72.6 5.8 2.1 2 1 0 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.6 ORY97399.1 - 1.5e-10 41.3 15.1 2.5e-10 40.5 15.1 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORY97399.1 - 4e-06 25.7 14.1 1.1e-05 24.2 14.1 1.9 1 1 0 1 1 1 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 ORY97399.1 - 0.00011 21.4 8.3 0.0003 20.0 0.1 2.2 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal Peptidase_U4 PF03419.13 ORY97399.1 - 0.19 11.0 8.4 0.11 11.7 6.1 1.5 1 1 0 1 1 1 0 Sporulation factor SpoIIGA FUSC-like PF12805.7 ORY97399.1 - 1.2 8.1 0.0 1.2 8.1 0.0 2.9 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS peroxidase PF00141.23 ORY97401.1 - 5.9e-46 157.0 0.0 8.9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Gram_pos_anchor PF00746.21 ORY97401.1 - 0.19 11.7 0.6 0.51 10.3 0.6 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif CH PF00307.31 ORY97402.1 - 3.1e-50 168.9 0.8 5.2e-25 87.7 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY97402.1 - 1.3e-14 53.7 0.1 1.3e-08 34.6 0.1 3.0 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.10 ORY97402.1 - 1.3e-13 50.8 1.5 3.9e-13 49.3 0.2 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TolA_bind_tri PF16331.5 ORY97402.1 - 0.0018 18.3 1.2 0.007 16.4 0.8 2.2 1 1 1 2 2 2 1 TolA binding protein trimerisation PriC PF07445.12 ORY97402.1 - 0.0055 16.6 2.2 0.02 14.8 2.2 2.1 1 1 0 1 1 1 1 Primosomal replication protein priC Spectrin PF00435.21 ORY97402.1 - 0.013 16.0 5.5 0.052 14.0 0.6 2.8 2 1 0 2 2 2 0 Spectrin repeat CH_2 PF06294.11 ORY97402.1 - 0.016 15.4 0.0 0.64 10.2 0.0 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein EF-hand_6 PF13405.6 ORY97402.1 - 0.017 15.0 0.0 0.12 12.3 0.0 2.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 ORY97402.1 - 0.021 14.7 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair K-box PF01486.17 ORY97402.1 - 0.024 14.8 2.4 0.25 11.6 1.5 2.6 2 0 0 2 2 2 0 K-box region EMP24_GP25L PF01105.24 ORY97402.1 - 0.053 13.5 0.7 5.5 6.9 0.6 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.12 ORY97402.1 - 0.21 12.1 2.2 1.2 9.6 1.1 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 ORY97402.1 - 0.23 11.8 0.5 0.81 10.0 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 ORY97402.1 - 0.37 10.8 2.5 0.69 10.0 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 ORY97402.1 - 0.45 8.4 4.2 0.75 7.7 2.1 2.0 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.12 ORY97402.1 - 0.68 10.0 5.6 0.24 11.5 1.0 2.6 3 1 1 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hep_59 PF07052.11 ORY97403.1 - 9.3e-32 109.9 0.8 9.3e-32 109.9 0.8 2.7 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Pyr_redox_2 PF07992.14 ORY97404.1 - 6.6e-48 163.4 0.0 9.2e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY97404.1 - 3e-14 53.4 0.0 8e-11 42.3 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 ORY97404.1 - 2.5e-11 43.8 0.0 8.6e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY97404.1 - 4.7e-11 41.4 2.8 2.5e-05 23.5 1.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY97404.1 - 4.3e-10 38.7 2.1 1.9e-05 24.2 0.4 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY97404.1 - 0.00011 21.5 0.1 0.027 14.0 0.1 2.7 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.6 ORY97404.1 - 0.00057 19.2 0.7 1.7 7.8 0.7 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 ORY97404.1 - 0.00059 19.6 2.4 0.19 11.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 ORY97404.1 - 0.04 13.9 0.2 11 6.1 0.0 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 ORY97404.1 - 0.053 13.4 0.1 15 5.5 0.0 2.7 2 0 0 2 2 2 0 EF hand Bac_luciferase PF00296.20 ORY97404.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Luciferase-like monooxygenase NAD_binding_8 PF13450.6 ORY97404.1 - 0.085 13.1 0.0 62 3.9 0.0 3.7 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY97404.1 - 0.17 11.0 0.0 4.1 6.4 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Arrestin_N PF00339.29 ORY97405.1 - 1.4e-12 47.9 0.0 2.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY97405.1 - 2.5e-05 24.8 0.0 0.0016 18.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY97405.1 - 0.00041 20.1 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like ERG4_ERG24 PF01222.17 ORY97406.1 - 1.5e-138 462.2 22.7 1.7e-138 462.1 22.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Plasmod_dom_1 PF09715.10 ORY97406.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Chromate_transp PF02417.15 ORY97406.1 - 0.057 13.6 0.1 0.057 13.6 0.1 2.6 2 1 0 2 2 2 0 Chromate transporter R3H PF01424.22 ORY97407.1 - 1.4e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain R3H-assoc PF13902.6 ORY97407.1 - 2.6e-05 24.6 2.4 5.7e-05 23.5 1.9 1.7 1 1 0 1 1 1 1 R3H-associated N-terminal domain SLX9 PF15341.6 ORY97407.1 - 0.15 12.5 2.6 0.46 10.9 0.3 2.2 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DnaJ_C PF01556.18 ORY97408.1 - 5.4e-42 143.4 0.1 7.6e-42 142.9 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY97408.1 - 8.4e-26 89.9 2.1 1.4e-25 89.2 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 ORY97408.1 - 0.033 14.1 0.2 0.087 12.8 0.1 1.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein Ribosom_S12_S23 PF00164.25 ORY97409.1 - 1.9e-50 169.2 1.2 2.4e-50 168.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 tRNA-synt_1c PF00749.21 ORY97410.1 - 7.6e-111 370.0 0.0 1e-110 369.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ORY97410.1 - 5.7e-41 140.3 0.6 1.2e-40 139.2 0.6 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 ORY97410.1 - 6e-05 23.0 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY97410.1 - 0.00058 20.0 0.1 0.0019 18.4 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GluRS_N PF18466.1 ORY97410.1 - 0.0035 17.7 0.0 0.0035 17.7 0.0 3.9 5 0 0 5 5 5 1 Glutamate--tRNA ligase N-terminal domain GST_C_3 PF14497.6 ORY97410.1 - 0.012 15.7 0.1 0.047 13.9 0.1 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC2_membrane PF01061.24 ORY97411.1 - 8.7e-73 244.2 69.7 4.4e-42 143.9 26.9 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY97411.1 - 1.9e-37 128.8 0.0 3e-20 73.1 0.0 2.7 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 ORY97411.1 - 2.6e-29 101.0 8.2 7.7e-22 77.0 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY97411.1 - 1.2e-12 48.3 0.0 2.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 ORY97411.1 - 8.7e-07 29.0 0.3 0.003 17.4 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY97411.1 - 2.5e-05 24.7 0.0 0.029 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY97411.1 - 6.1e-05 23.0 0.2 0.007 16.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY97411.1 - 0.00053 19.7 0.6 0.02 14.6 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY97411.1 - 0.0045 17.5 0.0 0.036 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORY97411.1 - 0.0057 16.3 0.1 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY97411.1 - 0.012 15.8 0.4 0.8 9.9 0.1 3.5 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ORY97411.1 - 0.025 14.9 0.1 0.85 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 ORY97411.1 - 0.031 14.4 0.1 9.1 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 ORY97411.1 - 0.13 11.9 0.6 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY97411.1 - 0.15 11.3 0.0 0.68 9.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 ORY97411.1 - 0.22 12.0 0.0 0.61 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY97411.1 - 0.42 10.8 2.5 0.94 9.7 0.1 2.9 4 0 0 4 4 3 0 AAA domain DUF1146 PF06612.11 ORY97411.1 - 0.71 10.0 9.8 1.2 9.2 2.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) ABC2_membrane_3 PF12698.7 ORY97411.1 - 5.6 6.0 54.6 0.24 10.4 20.6 3.3 3 1 0 3 3 3 0 ABC-2 family transporter protein Peptidase_M1 PF01433.20 ORY97412.1 - 2.3e-46 158.1 0.0 3.4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 ORY97412.1 - 8.6e-40 135.4 0.2 1.9e-39 134.3 0.2 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 ORY97412.1 - 5e-24 85.5 0.4 7.1e-24 85.0 0.4 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Pkinase PF00069.25 ORY97414.1 - 1e-62 211.9 0.0 1.2e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97414.1 - 2.7e-39 135.0 0.0 3.3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY97414.1 - 1.9e-06 26.9 0.0 3.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY97414.1 - 0.00031 20.1 0.0 0.00079 18.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY97414.1 - 0.0026 17.2 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY97414.1 - 0.048 13.3 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 ORY97414.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 ORY97414.1 - 0.099 12.5 0.0 0.39 10.6 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY97414.1 - 0.1 11.5 0.2 1 8.2 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain HSF_DNA-bind PF00447.17 ORY97415.1 - 8.8e-30 103.2 1.4 1.5e-29 102.4 1.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding BRE1 PF08647.11 ORY97415.1 - 0.0011 19.0 0.4 0.0023 18.0 0.4 1.5 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase DUF3972 PF13118.6 ORY97415.1 - 0.0047 17.4 0.9 0.0075 16.7 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3972) EMP24_GP25L PF01105.24 ORY97415.1 - 0.025 14.6 0.2 0.029 14.3 0.2 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ATG16 PF08614.11 ORY97415.1 - 0.083 13.1 1.1 0.13 12.5 1.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.13 ORY97415.1 - 0.092 13.5 0.7 0.2 12.4 0.1 1.8 2 0 0 2 2 2 0 Occludin homology domain Pkinase PF00069.25 ORY97418.1 - 2.3e-74 250.1 0.0 2.6e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97418.1 - 3.2e-40 138.1 0.0 4.2e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97418.1 - 5.6e-10 39.0 0.0 1.2e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY97418.1 - 6.4e-05 22.6 0.4 0.00017 21.2 0.4 1.6 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY97418.1 - 0.00044 19.3 0.2 0.00058 18.9 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY97418.1 - 0.00046 19.6 0.3 0.00074 18.9 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY97418.1 - 0.0048 16.8 0.1 0.01 15.8 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Phage_T7_Capsid PF05396.11 ORY97418.1 - 0.067 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein YrbL-PhoP_reg PF10707.9 ORY97418.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SeqA_N PF17206.3 ORY97418.1 - 0.12 11.7 0.5 4.7 6.6 0.1 3.1 3 1 0 3 3 3 0 SeqA protein N-terminal domain Glyco_hydro_72 PF03198.14 ORY97419.1 - 5.5e-131 436.5 5.7 7.1e-131 436.1 5.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ORY97419.1 - 3.3e-16 59.7 2.4 3.3e-16 59.7 2.4 2.7 2 1 0 2 2 2 1 X8 domain Cellulase PF00150.18 ORY97419.1 - 4.9e-06 26.2 0.6 2.6e-05 23.8 0.6 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 ORY97419.1 - 0.001 18.2 0.2 0.004 16.3 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain SUR7 PF06687.12 ORY97420.1 - 8.5e-16 58.2 11.7 1.2e-15 57.7 11.7 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF4293 PF14126.6 ORY97420.1 - 1.4 9.1 10.6 0.22 11.7 6.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2207 PF09972.9 ORY97420.1 - 2.7 6.6 4.1 4.4 5.9 4.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF996 PF06195.13 ORY97420.1 - 3 8.1 14.8 1.7 8.9 11.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF996) Biopterin_H PF00351.21 ORY97421.1 - 3.4e-163 542.4 0.0 4.2e-163 542.1 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT_4 PF13291.6 ORY97421.1 - 0.028 15.0 0.0 0.064 13.9 0.0 1.6 1 0 0 1 1 1 0 ACT domain CDC50 PF03381.15 ORY97422.1 - 4.1e-91 305.4 0.5 4.9e-91 305.1 0.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF202 PF02656.15 ORY97422.1 - 5.3 7.6 4.9 12 6.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Dynamin_M PF01031.20 ORY97423.1 - 3.9e-104 347.9 0.0 2e-103 345.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORY97423.1 - 8e-54 182.2 0.1 1.5e-53 181.3 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY97423.1 - 1.3e-32 111.8 2.7 1.5e-32 111.6 1.4 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY97423.1 - 0.00011 22.3 0.1 0.001 19.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY97423.1 - 0.022 15.1 0.0 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 ORY97423.1 - 0.051 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Snf7 PF03357.21 ORY97424.1 - 2.4e-28 98.9 23.5 2.4e-28 98.9 23.5 1.4 1 1 1 2 2 2 1 Snf7 Myb_DNA-bind_6 PF13921.6 ORY97424.1 - 0.043 14.1 0.3 0.1 12.9 0.3 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY97424.1 - 0.046 13.6 1.2 0.17 11.8 1.2 2.0 1 0 0 1 1 1 0 Myb DNA-binding like Ribosomal_60s PF00428.19 ORY97424.1 - 0.14 12.8 4.2 1.6 9.4 0.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein CsgF PF10614.9 ORY97424.1 - 0.63 10.3 4.2 0.92 9.7 0.8 2.1 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein MMR_HSR1_C PF08438.10 ORY97424.1 - 1 9.9 5.2 1.8 9.2 1.9 2.3 1 1 1 2 2 2 0 GTPase of unknown function C-terminal DUF733 PF05306.11 ORY97424.1 - 7.8 6.9 11.2 12 6.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF733) YlqD PF11068.8 ORY97424.1 - 8.9 6.7 20.3 1.6 9.1 12.8 2.3 1 1 1 2 2 2 0 YlqD protein DUF155 PF02582.14 ORY97425.1 - 1.8e-54 184.5 0.2 2.6e-54 184.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1073 PF06381.11 ORY97425.1 - 0.039 12.7 0.1 0.068 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Cpn60_TCP1 PF00118.24 ORY97426.1 - 4.7e-146 487.3 10.9 5.4e-146 487.1 10.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 ORY97426.1 - 0.071 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Cys_Met_Meta_PP PF01053.20 ORY97427.1 - 1.1e-38 132.7 0.0 1.6e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY97427.1 - 0.0069 15.6 0.0 0.019 14.2 0.0 1.7 3 0 0 3 3 3 1 Aminotransferase class I and II Pkinase PF00069.25 ORY97428.1 - 5.2e-74 248.9 0.0 6.3e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97428.1 - 2e-34 119.0 0.0 2.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97428.1 - 2.1e-05 24.0 0.0 3.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY97428.1 - 0.00058 19.9 0.2 0.12 12.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY97428.1 - 0.022 13.7 0.1 0.035 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY97428.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldedh PF00171.22 ORY97429.1 - 4.1e-85 286.0 0.0 4.9e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rol_Rep_N PF18106.1 ORY97429.1 - 0.053 13.8 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain DUF4684 PF15736.5 ORY97430.1 - 0.052 12.2 0.0 0.061 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) FIST PF08495.10 ORY97431.1 - 1.3e-07 31.8 0.0 1.9e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 FIST N domain ATP-gua_PtransN PF02807.15 ORY97431.1 - 0.14 12.6 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain WD40 PF00400.32 ORY97432.1 - 2.5e-07 31.3 0.0 1.3e-06 29.0 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat CRAL_TRIO PF00650.20 ORY97434.1 - 2.7e-12 46.7 0.0 4.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GATA PF00320.27 ORY97435.1 - 9.3e-14 50.8 6.0 1.6e-13 50.0 6.0 1.3 1 0 0 1 1 1 1 GATA zinc finger Miff PF05644.11 ORY97435.1 - 0.026 14.2 0.4 0.028 14.1 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Haem_bd PF14376.6 ORY97435.1 - 0.13 12.2 0.9 0.2 11.6 0.9 1.3 1 0 0 1 1 1 0 Haem-binding domain Paired_CXXCH_1 PF09699.10 ORY97435.1 - 1.2 9.0 5.2 0.13 12.0 0.9 1.7 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Suf PF05843.14 ORY97436.1 - 1.7e-17 64.4 7.8 0.021 14.8 0.0 5.8 4 2 1 5 5 5 5 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY97436.1 - 2.9e-13 49.4 21.1 0.22 12.4 0.0 12.1 6 5 7 13 13 13 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY97436.1 - 4.7e-09 36.6 6.5 2.8 8.5 0.0 7.6 7 1 0 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY97436.1 - 4e-08 32.8 2.9 0.05 12.7 0.0 5.1 3 2 1 4 4 4 3 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 ORY97436.1 - 1.2e-06 28.5 12.0 0.64 10.0 0.1 6.6 7 1 1 8 8 8 3 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 ORY97436.1 - 1.7e-05 24.9 0.2 0.076 13.1 0.0 2.9 2 0 0 2 2 2 2 Putative Mad3/BUB1 like region 1 protein TPR_8 PF13181.6 ORY97436.1 - 0.00016 21.6 19.9 0.022 14.9 0.0 7.9 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97436.1 - 0.00022 21.1 23.2 0.21 11.8 0.0 9.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY97436.1 - 0.0037 17.1 5.9 4.1 7.4 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY97436.1 - 0.0041 17.7 19.6 13 6.7 0.0 8.8 10 1 1 11 11 8 0 Tetratricopeptide repeat TAtT PF16811.5 ORY97436.1 - 0.0061 15.9 0.2 0.28 10.5 0.1 3.4 3 0 0 3 3 3 1 TRAP transporter T-component SNAP PF14938.6 ORY97436.1 - 0.012 15.1 3.8 0.46 9.9 0.1 4.1 5 0 0 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 ORY97436.1 - 0.016 15.5 14.4 0.28 11.5 0.2 6.4 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY97436.1 - 0.34 11.6 7.2 14 6.4 0.1 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY97436.1 - 0.84 9.8 7.3 10 6.4 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY97436.1 - 1.2 9.7 10.2 54 4.5 0.0 7.2 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97436.1 - 1.6 8.7 17.6 0.96 9.4 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat PPR PF01535.20 ORY97436.1 - 7.4 7.1 6.4 42 4.7 0.0 4.9 6 0 0 6 6 5 0 PPR repeat GAS PF13851.6 ORY97437.1 - 0.0093 15.3 22.9 0.013 14.8 22.9 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding KIP1 PF07765.12 ORY97437.1 - 0.016 15.3 14.9 0.26 11.4 8.2 2.1 2 0 0 2 2 2 0 KIP1-like protein ABC_tran_CTD PF16326.5 ORY97437.1 - 0.018 15.3 28.0 0.1 12.9 16.0 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain PilJ PF13675.6 ORY97437.1 - 0.02 14.9 8.6 0.22 11.6 2.5 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term SOAR PF16533.5 ORY97437.1 - 0.027 14.4 10.2 0.83 9.7 9.6 2.7 1 1 0 1 1 1 0 STIM1 Orai1-activating region MAD PF05557.13 ORY97437.1 - 0.027 12.8 22.2 0.031 12.6 22.2 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein BLOC1_2 PF10046.9 ORY97437.1 - 0.08 13.3 13.0 1.9 8.9 8.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 STN1_2 PF09170.10 ORY97437.1 - 0.1 12.8 7.9 0.13 12.4 7.9 1.1 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 AAA_23 PF13476.6 ORY97437.1 - 0.17 12.3 20.5 0.24 11.9 20.5 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 ORY97437.1 - 0.19 11.8 12.1 1.3 9.1 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4541 PF15074.6 ORY97437.1 - 0.27 11.9 7.4 0.11 13.1 4.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4541) Exonuc_VII_L PF02601.15 ORY97437.1 - 0.29 10.7 12.9 0.32 10.5 12.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Transcrip_reg PF01709.20 ORY97437.1 - 0.33 10.3 8.5 0.43 10.0 8.5 1.3 1 0 0 1 1 1 0 Transcriptional regulator NPV_P10 PF05531.12 ORY97437.1 - 0.34 11.4 4.8 1.4 9.4 2.0 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 ORY97437.1 - 0.47 10.3 14.6 1.3 8.9 4.3 2.1 1 1 1 2 2 2 0 Sec34-like family Spc7 PF08317.11 ORY97437.1 - 0.49 9.2 25.2 1.1 8.0 25.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Katanin_con80 PF13925.6 ORY97437.1 - 0.69 9.9 7.4 0.28 11.2 1.9 2.0 1 1 1 2 2 2 0 con80 domain of Katanin FlaC_arch PF05377.11 ORY97437.1 - 0.81 10.1 12.3 0.19 12.1 1.9 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Enkurin PF13864.6 ORY97437.1 - 1.5 9.3 22.2 0.47 10.9 10.6 2.7 1 1 0 2 2 2 0 Calmodulin-binding ALMT PF11744.8 ORY97437.1 - 1.9 7.2 7.1 2.4 6.9 7.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Nsp1_C PF05064.13 ORY97437.1 - 2 8.2 18.3 3.6 7.4 4.5 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region T2SSM PF04612.12 ORY97437.1 - 2.1 8.4 10.4 6.3 6.8 10.5 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Prefoldin_2 PF01920.20 ORY97437.1 - 2.5 8.1 27.8 1.2 9.1 9.3 3.3 1 1 2 3 3 3 0 Prefoldin subunit DUF1090 PF06476.12 ORY97437.1 - 2.9 8.1 20.6 18 5.5 19.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) DUF4407 PF14362.6 ORY97437.1 - 3.2 7.0 15.4 4.5 6.5 15.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 ORY97437.1 - 3.5 7.2 14.9 19 4.8 14.9 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tho2 PF11262.8 ORY97437.1 - 3.6 6.7 13.5 3.8 6.6 12.6 1.5 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HemX PF04375.14 ORY97437.1 - 3.6 6.8 16.6 0.35 10.1 10.1 1.6 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase NBD_C PF17042.5 ORY97437.1 - 3.7 8.0 5.7 4.2 7.9 5.2 1.3 1 1 0 1 1 1 0 Nucleotide-binding C-terminal domain Occludin_ELL PF07303.13 ORY97437.1 - 4 8.2 16.2 13 6.6 0.6 2.5 1 1 2 3 3 3 0 Occludin homology domain Seryl_tRNA_N PF02403.22 ORY97437.1 - 4.9 7.4 19.3 1.3 9.3 12.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 ORY97437.1 - 5 7.7 33.9 1.4 9.5 22.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region LMBR1 PF04791.16 ORY97437.1 - 7.6 5.3 8.9 9.2 5.0 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4164 PF13747.6 ORY97437.1 - 8.6 6.7 23.2 5.6 7.3 9.9 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF812 PF05667.11 ORY97437.1 - 10 4.9 24.8 1.7e+02 0.8 25.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Peptidase_M50B PF13398.6 ORY97438.1 - 2.6e-51 174.1 19.4 3.4e-51 173.7 19.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF3185 PF11381.8 ORY97438.1 - 0.009 16.0 0.0 0.009 16.0 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3185) Oxidored_FMN PF00724.20 ORY97439.1 - 1.6e-78 264.4 0.0 2e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Bac_DNA_binding PF00216.21 ORY97439.1 - 0.099 12.9 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial DNA-binding protein YdjO PF14169.6 ORY97440.1 - 0.13 12.0 1.0 3.3 7.5 0.0 2.3 1 1 1 2 2 2 0 Cold-inducible protein YdjO ICL PF00463.21 ORY97441.1 - 0.0025 16.4 0.2 0.0039 15.7 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family COX16 PF14138.6 ORY97442.1 - 5e-29 100.6 0.0 6.2e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Thioredoxin PF00085.20 ORY97443.1 - 1.4e-19 70.0 0.1 6.5e-19 67.8 0.1 2.0 1 1 2 3 3 3 1 Thioredoxin Glutaredoxin PF00462.24 ORY97443.1 - 3.2e-14 52.9 0.0 1.3e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Phosducin PF02114.16 ORY97443.1 - 4e-05 22.7 0.0 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 ORY97443.1 - 0.00076 19.9 0.1 0.051 14.0 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY97443.1 - 0.0013 19.0 0.1 0.065 13.6 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY97443.1 - 0.034 14.1 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 ORY97443.1 - 0.057 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 ORY97443.1 - 0.2 11.0 0.1 0.36 10.2 0.1 1.5 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family Mcl1_mid PF12341.8 ORY97444.1 - 1.3e-88 297.2 0.0 4.5e-86 288.9 0.0 2.3 2 0 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 ORY97444.1 - 5.2e-21 74.7 0.1 7.9e-11 42.1 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY97444.1 - 3.1e-19 69.0 9.9 1.3e-05 25.8 0.1 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat MMS1_N PF10433.9 ORY97444.1 - 0.0063 15.2 0.2 5.1 5.6 0.1 3.5 3 1 1 4 4 4 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nup160 PF11715.8 ORY97444.1 - 0.043 12.5 0.1 1 7.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF2457 PF10446.9 ORY97444.1 - 0.2 10.8 8.5 0.32 10.1 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vps26 PF03643.15 ORY97445.1 - 7.3e-127 422.1 4.0 8.5e-127 421.8 4.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 ORY97445.1 - 0.015 15.4 1.6 0.28 11.2 0.1 3.0 2 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY97445.1 - 0.088 13.3 0.1 0.85 10.1 0.0 2.7 1 1 1 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF2101 PF09874.9 ORY97446.1 - 0.048 13.4 0.5 0.044 13.5 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) CMAS PF02353.20 ORY97447.1 - 2.9e-61 207.2 0.7 3.6e-61 206.9 0.7 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY97447.1 - 3.6e-13 50.0 0.0 7.9e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY97447.1 - 2.7e-11 44.0 0.0 6.5e-11 42.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY97447.1 - 8.2e-10 38.8 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY97447.1 - 1.5e-08 35.3 0.0 3.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY97447.1 - 3.7e-07 30.1 0.0 5.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY97447.1 - 9.8e-05 22.0 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 ORY97447.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 NodS PF05401.11 ORY97447.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 ORY97447.1 - 0.0034 17.2 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4858 PF16150.5 ORY97447.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) PrmA PF06325.13 ORY97447.1 - 0.084 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 ORY97447.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PIP5K PF01504.18 ORY97448.1 - 1.6e-99 332.6 4.1 2.6e-99 331.9 4.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FucT_N PF18025.1 ORY97448.1 - 0.079 13.4 0.1 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain UCMA PF17085.5 ORY97448.1 - 0.13 12.3 6.0 0.1 12.6 0.7 2.3 2 0 0 2 2 2 0 Unique cartilage matrix associated protein Acyl-CoA_dh_1 PF00441.24 ORY97449.1 - 1.2e-34 119.7 0.4 1.8e-34 119.1 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY97449.1 - 3.4e-22 78.5 0.0 1.8e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY97449.1 - 3.5e-13 50.2 0.0 6.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY97449.1 - 4e-13 49.8 0.7 8.5e-13 48.7 0.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY97449.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 ORY97449.1 - 0.14 12.8 0.3 11 6.5 0.1 2.3 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal F-box-like PF12937.7 ORY97450.1 - 5.6e-05 22.9 3.8 5.6e-05 22.9 3.8 2.0 2 0 0 2 2 2 1 F-box-like TPR_9 PF13371.6 ORY97450.1 - 0.00031 20.8 0.7 0.00088 19.4 0.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.33 ORY97450.1 - 0.00035 20.4 1.6 0.0014 18.4 1.6 2.2 1 0 0 1 1 1 1 F-box domain TPR_16 PF13432.6 ORY97450.1 - 0.0059 17.2 0.5 0.019 15.6 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97450.1 - 0.0095 16.0 1.4 0.029 14.4 1.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_3 PF07720.12 ORY97450.1 - 8.8 6.4 5.9 0.84 9.7 1.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY97451.1 - 1e-05 25.3 0.6 3.4e-05 23.7 0.6 2.0 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 ORY97451.1 - 3.4e-05 23.6 0.9 0.042 14.0 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY97451.1 - 7.8e-05 22.7 1.9 0.00025 21.1 1.9 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.33 ORY97451.1 - 9.7e-05 22.1 0.1 0.0004 20.2 0.1 2.1 1 0 0 1 1 1 1 F-box domain TPR_16 PF13432.6 ORY97451.1 - 0.00072 20.1 0.4 0.00072 20.1 0.4 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97451.1 - 0.016 16.0 1.8 0.1 13.5 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY97451.1 - 0.075 13.3 0.5 0.2 11.9 0.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ORY97451.1 - 0.19 11.5 0.4 0.73 9.6 0.1 2.1 2 0 0 2 2 2 0 TPR repeat LRR_2 PF07723.13 ORY97451.1 - 0.31 11.8 2.1 30 5.5 0.2 3.4 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY97451.1 - 0.77 10.0 3.6 16 5.8 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat SAP PF02037.27 ORY97453.1 - 5.2e-13 48.4 0.4 3.1e-12 45.9 0.5 2.2 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 ORY97453.1 - 5.4e-05 22.9 18.2 0.0018 18.0 1.2 3.2 3 1 0 3 3 3 2 Tho1/MOS11 C-terminal domain DUF3439 PF11921.8 ORY97453.1 - 0.0035 17.3 2.8 0.0057 16.6 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) TEBP_beta PF07404.11 ORY97453.1 - 0.012 14.9 10.8 0.019 14.3 10.8 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) HeH PF12949.7 ORY97453.1 - 0.013 15.1 0.5 0.039 13.7 0.5 1.8 1 0 0 1 1 1 0 HeH/LEM domain Med3 PF11593.8 ORY97453.1 - 0.034 13.3 8.4 0.043 13.0 8.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Apt1 PF10351.9 ORY97453.1 - 0.21 10.4 6.0 0.28 10.0 6.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRN3 PF05327.11 ORY97453.1 - 1.3 7.5 4.0 1.4 7.3 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dicty_REP PF05086.12 ORY97453.1 - 3.5 5.5 5.7 4.3 5.2 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.6 ORY97453.1 - 5.1 7.3 9.4 5.5 7.1 8.3 1.6 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Ribosomal_S10 PF00338.22 ORY97454.1 - 1.2e-32 112.0 0.0 1.4e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SPRY PF00622.28 ORY97455.1 - 2.6e-24 85.6 0.3 4.4e-24 84.9 0.3 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 ORY97455.1 - 2.6e-07 30.6 0.0 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY97455.1 - 1.1e-05 25.2 0.7 4.4e-05 23.3 0.1 2.3 3 0 0 3 3 3 1 LisH DUF4050 PF13259.6 ORY97456.1 - 2.1e-15 57.5 0.6 2.1e-09 37.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) ArabFuran-catal PF09206.11 ORY97457.1 - 0.063 12.6 0.1 0.075 12.3 0.1 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic Glyco_hydro_15 PF00723.21 ORY97458.1 - 3.1e-81 273.5 2.1 5e-81 272.8 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_21 PF03370.13 ORY97458.1 - 9.2e-10 38.7 5.5 1.9e-09 37.6 5.5 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) Med3 PF11593.8 ORY97458.1 - 0.52 9.4 12.4 0.92 8.6 12.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CBM53 PF16760.5 ORY97458.1 - 0.8 10.3 7.3 12 6.6 7.2 2.9 1 1 1 2 2 2 0 Starch/carbohydrate-binding module (family 53) Mucin PF01456.17 ORY97458.1 - 7.3 6.6 33.4 0.42 10.6 27.5 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_hydro_15 PF00723.21 ORY97459.1 - 2.3e-78 264.0 0.8 3.2e-78 263.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_21 PF03370.13 ORY97459.1 - 2.8e-11 43.6 3.2 6.3e-11 42.4 3.2 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY97459.1 - 0.0047 17.5 6.7 0.12 13.0 6.0 3.1 1 1 1 2 2 2 2 Starch/carbohydrate-binding module (family 53) Dicty_REP PF05086.12 ORY97459.1 - 0.43 8.5 4.8 0.62 8.0 4.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PLDc_2 PF13091.6 ORY97460.1 - 2.2e-17 63.2 1.1 3.1e-07 30.4 0.0 4.0 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 ORY97460.1 - 3.4e-17 61.8 2.5 1.5e-09 37.6 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 ORY97460.1 - 1.2e-11 44.6 1.4 3.1e-11 43.2 1.4 1.7 1 0 0 1 1 1 1 PX domain PH PF00169.29 ORY97460.1 - 6.6e-05 23.4 0.9 0.00024 21.6 0.9 2.0 1 0 0 1 1 1 1 PH domain Joubert PF15392.6 ORY97460.1 - 4.7 6.8 8.9 0.15 11.8 1.8 2.0 2 0 0 2 2 2 0 Joubert syndrome-associated HMG-CoA_red PF00368.18 ORY97461.1 - 1.6e-144 481.4 2.9 2.2e-144 481.0 2.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 ORY97461.1 - 1.3e-18 67.3 4.3 2.9e-18 66.2 4.3 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ORY97461.1 - 3.6e-09 35.3 9.0 7.7e-09 34.2 9.0 1.4 1 0 0 1 1 1 1 Patched family HPIH PF13323.6 ORY97461.1 - 0.035 14.0 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain with HPIH motif CAP_N PF01213.19 ORY97461.1 - 0.83 9.1 2.5 0.67 9.4 0.7 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1539 PF07560.11 ORY97462.1 - 0.019 15.0 0.3 0.045 13.8 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF1631 PF07793.11 ORY97462.1 - 0.13 10.6 17.8 0.18 10.2 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Golgin_A5 PF09787.9 ORY97462.1 - 0.67 9.4 12.8 0.29 10.6 9.0 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4795 PF16043.5 ORY97462.1 - 0.87 9.1 10.6 2.4 7.7 8.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1178 PF06676.11 ORY97462.1 - 4.3 7.7 7.3 11 6.5 7.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) DHHC PF01529.20 ORY97463.1 - 4.5e-35 120.7 13.1 4.5e-35 120.7 13.1 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase SRP-alpha_N PF04086.13 ORY97464.1 - 0.081 12.8 3.3 0.097 12.6 3.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAP1 PF08601.10 ORY97465.1 - 8.8e-14 52.0 2.0 8.8e-14 52.0 2.0 2.1 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 ORY97465.1 - 7.3e-11 42.0 15.6 2.5e-08 33.9 11.1 2.4 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY97465.1 - 0.0015 18.6 20.8 0.012 15.6 10.6 2.4 1 1 1 2 2 2 2 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 ORY97465.1 - 0.0036 17.5 5.6 0.007 16.6 5.6 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TPD52 PF04201.15 ORY97465.1 - 0.0043 16.7 0.9 0.008 15.8 0.9 1.4 1 0 0 1 1 1 1 Tumour protein D52 family Vac_Fusion PF02346.16 ORY97465.1 - 0.027 14.1 2.2 0.032 13.8 0.9 1.9 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 WXG100 PF06013.12 ORY97465.1 - 0.064 13.5 0.6 0.21 11.9 0.3 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Muted PF14942.6 ORY97465.1 - 0.081 13.3 7.9 0.33 11.3 7.1 2.2 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein FlaC_arch PF05377.11 ORY97465.1 - 0.12 12.8 1.8 0.29 11.6 1.8 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 ORY97465.1 - 0.26 10.8 3.3 0.33 10.5 3.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5595 PF18077.1 ORY97465.1 - 1.7 8.8 6.4 3.8 7.7 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) ACR_tran PF00873.19 ORY97466.1 - 0.094 10.4 3.1 0.15 9.7 3.1 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family HMMR_N PF15905.5 ORY97466.1 - 0.13 11.7 43.9 0.064 12.7 18.5 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DASH_Dam1 PF08653.10 ORY97466.1 - 3 7.7 8.3 0.63 9.9 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 BRE1 PF08647.11 ORY97466.1 - 4.8 7.3 36.7 0.47 10.6 5.2 3.9 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase CP12 PF02672.15 ORY97466.1 - 6.1 7.7 10.1 20 6.0 0.8 3.7 3 1 1 4 4 4 0 CP12 domain F-box PF00646.33 ORY97474.1 - 1.2e-08 34.6 0.6 2.2e-08 33.8 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY97474.1 - 5.9e-08 32.5 0.9 5.9e-08 32.5 0.9 1.6 2 0 0 2 2 2 1 F-box-like Peptidase_M22 PF00814.25 ORY97476.1 - 1.7e-83 280.5 0.0 1.9e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 ORY97476.1 - 0.0044 16.7 0.0 0.0085 15.8 0.0 1.4 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus Pkinase PF00069.25 ORY97477.1 - 4e-49 167.3 0.0 4.5e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97477.1 - 1.1e-24 87.1 0.0 1.3e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97477.1 - 0.0019 17.6 0.2 0.0052 16.1 0.2 1.7 1 1 0 1 1 1 1 Kinase-like Ycf34 PF10718.9 ORY97477.1 - 0.26 12.0 1.8 0.81 10.4 0.9 2.1 1 1 1 2 2 2 0 Hypothetical chloroplast protein Ycf34 Ysc84 PF04366.12 ORY97478.1 - 1.8e-38 131.2 0.5 3.6e-38 130.2 0.5 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator DNA_pol_E_B PF04042.16 ORY97479.1 - 6.3e-35 120.4 0.6 1e-34 119.8 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 ORY97479.1 - 3.6e-25 89.4 0.2 1.2e-22 81.1 0.2 2.2 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.6 ORY97479.1 - 0.059 12.7 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily tRNA-synt_2 PF00152.20 ORY97482.1 - 4e-79 265.9 0.2 5.8e-79 265.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY97482.1 - 0.00029 20.8 0.3 0.00062 19.7 0.3 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY97482.1 - 0.13 11.8 2.1 9.5 5.6 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) AUX_IAA PF02309.16 ORY97482.1 - 0.19 11.6 5.7 0.28 11.0 0.0 3.0 3 0 0 3 3 3 0 AUX/IAA family Spa1_C PF18218.1 ORY97482.1 - 0.28 11.6 2.2 0.77 10.2 0.4 2.3 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain Sas10_Utp3 PF04000.15 ORY97483.1 - 2e-19 70.0 1.1 5.6e-19 68.6 0.1 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TelA PF05816.11 ORY97483.1 - 0.00086 18.5 0.5 0.0095 15.0 0.2 2.3 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) ApoB100_C PF12491.8 ORY97483.1 - 0.0046 16.9 0.4 0.016 15.2 0.4 1.9 1 1 0 1 1 1 1 Apolipoprotein B100 C terminal Endotoxin_N PF03945.14 ORY97483.1 - 0.48 10.1 2.0 0.61 9.7 0.1 1.9 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF2894 PF11445.8 ORY97483.1 - 1.5 9.3 6.7 0.14 12.6 1.5 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) DUF4286 PF14114.6 ORY97484.1 - 0.0061 17.0 0.7 0.011 16.2 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) Polysacc_deac_1 PF01522.21 ORY97485.1 - 3.6e-11 43.0 0.0 7.4e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase Aminotran_1_2 PF00155.21 ORY97486.1 - 7.7e-65 219.4 0.0 8.9e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY97486.1 - 1.3e-06 27.9 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY97486.1 - 1.4e-06 27.8 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORY97486.1 - 4.2e-05 22.2 0.0 6.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY97486.1 - 0.00084 18.4 0.0 0.0033 16.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_3 PF00202.21 ORY97486.1 - 0.00086 18.1 0.0 0.0038 16.0 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-III Comm PF15957.5 ORY97490.1 - 0.00067 20.0 0.2 0.0011 19.3 0.2 1.3 1 1 0 1 1 1 1 Commissureless CopD PF05425.13 ORY97490.1 - 0.021 15.2 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein D FAM220 PF15487.6 ORY97490.1 - 0.06 13.0 0.0 0.073 12.7 0.0 1.0 1 0 0 1 1 1 0 FAM220 family WBP-1 PF11669.8 ORY97490.1 - 0.085 13.5 0.6 0.34 11.6 0.6 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 Gar1 PF04410.14 ORY97491.1 - 1.2e-36 125.8 0.0 1.4e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RRM_1 PF00076.22 ORY97492.1 - 5.3e-16 58.2 0.1 7.6e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY97492.1 - 5.1e-05 23.3 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 ORY97492.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 ORY97493.1 - 1e-97 327.9 22.9 7.2e-74 249.3 14.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY97493.1 - 4.5e-26 91.6 30.5 2.7e-24 85.7 18.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 ORY97493.1 - 0.001 19.6 4.9 0.0017 18.9 4.9 1.3 1 0 0 1 1 1 1 Plexin repeat MCR_alpha_N PF02745.15 ORY97493.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain DUF4282 PF14110.6 ORY97493.1 - 0.049 14.4 0.9 0.049 14.4 0.9 4.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4282) DUF1686 PF07937.11 ORY97493.1 - 0.18 11.7 11.1 0.12 12.3 2.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1686) RNA_pol_Rpb2_6 PF00562.28 ORY97494.1 - 8.6e-112 374.0 0.8 2.3e-111 372.6 0.8 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY97494.1 - 8.3e-31 107.1 0.0 1.4e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 ORY97494.1 - 4.8e-28 97.1 0.0 1.1e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 ORY97494.1 - 3.4e-24 84.6 0.0 6.7e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 ORY97494.1 - 3.9e-22 78.4 0.0 1e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ORY97494.1 - 1.2e-17 64.1 0.1 2.7e-17 63.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 FYVE PF01363.21 ORY97494.1 - 0.96 9.6 3.2 3.8 7.7 3.2 1.9 1 1 0 1 1 1 0 FYVE zinc finger Homeodomain PF00046.29 ORY97495.1 - 6.1e-15 54.8 5.1 1.1e-14 54.0 5.1 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORY97495.1 - 0.0095 15.7 0.1 0.03 14.1 0.0 1.9 1 1 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 ORY97495.1 - 0.027 14.4 1.9 0.038 13.9 0.1 2.1 2 0 0 2 2 2 0 Homeobox KN domain DUF2381 PF09544.10 ORY97497.1 - 0.036 13.6 9.4 0.047 13.2 4.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) ATP-synt_ab_N PF02874.23 ORY97497.1 - 0.22 12.0 0.2 0.55 10.8 0.1 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain PAC2 PF09754.9 ORY97498.1 - 2.1e-24 86.7 0.0 2.5e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 PAC2 family PDEase_I PF00233.19 ORY97499.1 - 1e-71 241.5 0.0 1.7e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Tcf25 PF04910.14 ORY97499.1 - 0.013 14.6 0.2 0.23 10.5 0.1 2.0 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Response_reg PF00072.24 ORY97499.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Response regulator receiver domain Allantoicase PF03561.15 ORY97500.1 - 5.5e-84 279.3 0.0 5.9e-44 149.5 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 ORY97500.1 - 7.9e-49 166.0 0.0 1.3e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate lyase TPR_1 PF00515.28 ORY97501.1 - 6.7e-08 32.0 4.7 0.0012 18.6 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY97501.1 - 9.3e-07 28.4 4.2 0.0016 18.0 0.1 3.6 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 ORY97501.1 - 2e-06 27.4 6.2 0.00094 19.1 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY97501.1 - 8e-06 26.4 4.8 0.011 16.4 0.6 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97501.1 - 0.001 19.7 1.9 2.4 9.2 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY97501.1 - 0.006 16.7 3.4 0.11 12.8 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY97501.1 - 0.0083 16.1 0.3 0.03 14.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY97501.1 - 0.015 15.8 5.1 0.26 11.8 2.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat EPSP_synthase PF00275.20 ORY97501.1 - 0.054 12.2 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) RPAP1_N PF08621.10 ORY97501.1 - 0.21 11.4 4.3 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 RPAP1-like, N-terminal TPR_6 PF13174.6 ORY97501.1 - 0.38 11.5 3.4 21 6.0 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 ORY97502.1 - 4.6e-21 74.4 12.0 8.7e-21 73.5 12.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY97502.1 - 8e-07 28.8 8.6 1.4e-06 28.1 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 ORY97502.1 - 3.2e-06 26.8 0.0 7.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 ORY97502.1 - 0.00097 19.0 9.9 0.018 14.9 10.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY97502.1 - 0.0015 18.8 12.0 0.0027 18.0 12.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY97502.1 - 0.14 12.1 11.0 0.24 11.3 11.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 ORY97502.1 - 0.14 12.1 3.7 0.24 11.4 3.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 ORY97502.1 - 0.16 11.9 11.0 0.27 11.1 11.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 ORY97502.1 - 0.19 11.9 2.8 0.66 10.1 2.8 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 ORY97502.1 - 0.21 11.6 7.3 0.82 9.7 7.6 1.9 1 1 1 2 2 2 0 RING-type zinc-finger Torus PF16131.5 ORY97502.1 - 0.59 10.9 2.7 0.56 10.9 0.1 2.2 2 0 0 2 2 2 0 Torus domain FYVE PF01363.21 ORY97502.1 - 0.74 10.0 4.4 1.6 9.0 4.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger CorA PF01544.18 ORY97503.1 - 2.6e-50 171.4 0.1 3.1e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4551 PF15087.6 ORY97504.1 - 0.37 9.6 3.3 0.43 9.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RIC1 PF07064.13 ORY97505.1 - 3.8e-84 282.0 0.0 6.9e-84 281.2 0.0 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 ORY97505.1 - 0.00099 19.4 0.1 1.2 9.5 0.0 4.2 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain F5_F8_type_C PF00754.25 ORY97506.1 - 5.6e-06 26.5 0.0 8.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 ORY97506.1 - 0.0088 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Laminin_N PF00055.17 ORY97506.1 - 0.1 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) polyprenyl_synt PF00348.17 ORY97508.1 - 1e-72 244.3 0.0 1.6e-72 243.7 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 ORY97508.1 - 0.0068 15.9 0.4 0.39 10.2 0.2 2.1 2 0 0 2 2 2 2 Squalene/phytoene synthase Orn_Arg_deC_N PF02784.16 ORY97509.1 - 4.4e-79 265.4 0.0 5.5e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORY97509.1 - 1.1e-21 76.8 0.1 1.7e-21 76.2 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 ORY97509.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ABC1 PF03109.16 ORY97510.1 - 4.1e-30 104.4 0.1 1e-29 103.1 0.1 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ORY97510.1 - 6.4e-05 23.0 0.3 0.00084 19.3 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.11 ORY97510.1 - 0.00076 19.2 0.1 0.0017 18.0 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 ORY97510.1 - 0.0069 16.0 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 RIO1 family TLD PF07534.16 ORY97512.1 - 1.5e-40 138.6 0.0 1.7e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 TLD G6PD_C PF02781.16 ORY97513.1 - 1.9e-113 378.5 0.0 3.3e-113 377.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORY97513.1 - 2.3e-38 132.6 0.3 7.8e-38 130.9 0.0 2.0 3 0 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Arteri_nucleo PF01481.16 ORY97513.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein RRF_GI PF12614.8 ORY97514.1 - 0.075 13.2 1.8 0.16 12.1 0.8 1.9 1 1 1 2 2 2 0 Ribosome recycling factor FUSC PF04632.12 ORY97514.1 - 2.5 6.5 10.4 3.3 6.1 10.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SANT_DAMP1_like PF16282.5 ORY97515.1 - 1.1e-32 112.1 5.8 2.2e-32 111.1 5.8 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 ORY97515.1 - 1.2e-05 25.2 0.0 3.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_7 PF15963.5 ORY97515.1 - 0.011 15.7 1.2 0.024 14.5 1.2 1.7 1 0 0 1 1 1 0 Myb DNA-binding like QWRF PF04484.12 ORY97515.1 - 0.035 13.8 0.3 0.035 13.8 0.3 1.5 2 0 0 2 2 2 0 QWRF family Myb_DNA-bind_6 PF13921.6 ORY97515.1 - 0.049 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain F-box-like PF12937.7 ORY97516.1 - 3.3e-05 23.7 3.3 3.3e-05 23.7 3.3 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY97516.1 - 5.6e-05 22.9 4.3 0.00016 21.5 1.7 2.7 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY97516.1 - 0.011 15.6 0.7 0.026 14.4 0.6 1.8 1 1 0 1 1 1 0 F-box DHHC PF01529.20 ORY97517.1 - 2.5e-39 134.4 15.0 2.5e-39 134.4 15.0 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase RTA1 PF04479.13 ORY97517.1 - 0.11 12.1 5.3 0.2 11.2 5.3 1.5 1 1 0 1 1 1 0 RTA1 like protein 7tm_7 PF08395.12 ORY97517.1 - 9.2 5.4 17.4 0.13 11.4 7.2 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor Tim17 PF02466.19 ORY97518.1 - 9e-27 93.7 5.6 1.4e-26 93.0 5.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Myb_DNA-binding PF00249.31 ORY97519.1 - 6.9e-41 138.2 4.3 3.4e-14 52.8 0.0 3.2 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY97519.1 - 2.9e-34 117.1 0.3 2.3e-14 53.4 0.0 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY97519.1 - 0.00066 20.0 4.9 8.5 6.8 0.1 3.9 3 2 0 3 3 3 3 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 ORY97519.1 - 0.011 15.8 1.7 3.2 7.9 1.7 3.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 ORY97519.1 - 0.041 13.9 0.0 10 6.2 0.0 2.9 1 1 1 3 3 3 0 SLIDE DUF1923 PF09083.10 ORY97519.1 - 0.063 13.0 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) RACo_linker PF17650.1 ORY97519.1 - 0.065 13.1 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 RACo linker region Myb_DNA-bind_7 PF15963.5 ORY97519.1 - 0.072 13.0 0.1 2.4 8.1 0.0 2.5 3 0 0 3 3 3 0 Myb DNA-binding like IU_nuc_hydro PF01156.19 ORY97521.1 - 4.7e-61 207.0 0.0 6e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.16 ORY97524.1 - 1.7e-26 93.0 20.5 5e-26 91.5 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YwiC PF14256.6 ORY97524.1 - 0.01 16.1 0.6 0.01 16.1 0.6 2.7 3 1 0 3 3 3 0 YwiC-like protein PIG-P PF08510.12 ORY97524.1 - 0.33 10.9 2.5 15 5.5 0.0 3.5 3 1 0 3 3 3 0 PIG-P Abhydrolase_9_N PF15420.6 ORY97524.1 - 1.3 9.0 4.5 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus MFS_1 PF07690.16 ORY97525.1 - 2.1e-21 76.2 6.1 6.8e-16 58.1 2.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ORY97526.1 - 0.00061 18.9 0.4 0.0018 17.4 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY97526.1 - 0.03 14.4 8.5 0.07 13.3 8.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain VHS PF00790.19 ORY97527.1 - 2.2e-41 141.0 1.6 1.2e-39 135.4 0.0 2.6 3 0 0 3 3 3 1 VHS domain FYVE PF01363.21 ORY97527.1 - 1.3e-17 63.7 7.3 2.5e-17 62.8 7.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 ORY97527.1 - 2.2e-05 24.1 7.9 0.043 13.7 1.1 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 ORY97527.1 - 0.0023 18.2 0.4 0.0055 17.0 0.4 1.7 1 0 0 1 1 1 1 GAT domain OAD_gamma PF04277.13 ORY97527.1 - 0.012 16.2 0.5 0.03 14.9 0.5 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Borrelia_P83 PF05262.11 ORY97527.1 - 0.018 13.5 2.0 0.026 13.0 2.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HEAT_2 PF13646.6 ORY97527.1 - 0.034 14.5 0.1 0.19 12.1 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats Npa1 PF11707.8 ORY97527.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Hrs_helical PF12210.8 ORY97527.1 - 0.083 13.4 0.5 0.083 13.4 0.5 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DZR PF12773.7 ORY97527.1 - 0.55 10.3 9.6 1e+02 3.1 9.6 2.6 1 1 0 1 1 1 0 Double zinc ribbon FYVE_2 PF02318.16 ORY97527.1 - 5.2 7.3 15.9 0.12 12.6 6.5 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger HSP90 PF00183.18 ORY97528.1 - 2e-101 340.5 10.4 1.3e-100 337.8 0.3 2.7 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.6 ORY97528.1 - 5.6e-12 45.7 0.2 1.6e-11 44.2 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY97528.1 - 6.9e-08 33.0 0.2 1.3e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5491 PF17595.2 ORY97528.1 - 0.022 15.1 0.1 0.062 13.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5491) Peptidase_S64 PF08192.11 ORY97528.1 - 0.072 11.6 3.3 0.31 9.5 3.1 1.9 2 0 0 2 2 2 0 Peptidase family S64 RCDG1 PF15725.5 ORY97529.1 - 9 6.8 8.0 0.97 9.9 2.3 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Peptidase_S8 PF00082.22 ORY97530.1 - 1.6e-39 136.0 16.3 2.3e-39 135.4 16.3 1.3 1 0 0 1 1 1 1 Subtilase family RabGAP-TBC PF00566.18 ORY97531.1 - 1e-58 198.5 0.3 3.4e-58 196.8 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mod_r PF07200.13 ORY97531.1 - 0.017 15.3 6.7 0.017 15.3 6.7 3.1 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ETC_C1_NDUFA5 PF04716.14 ORY97531.1 - 0.11 12.4 1.4 15 5.5 0.1 2.7 2 0 0 2 2 2 0 ETC complex I subunit conserved region Fungal_TACC PF12709.7 ORY97531.1 - 0.22 12.0 3.6 2.2 8.8 0.0 3.1 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_1 PF00170.21 ORY97531.1 - 0.3 11.2 9.2 0.51 10.5 1.1 3.8 2 1 1 3 3 3 0 bZIP transcription factor Prp19 PF08606.11 ORY97531.1 - 0.39 10.7 5.5 3.5 7.7 0.1 3.5 4 0 0 4 4 4 0 Prp19/Pso4-like FlaC_arch PF05377.11 ORY97531.1 - 0.82 10.1 8.6 7.8 7.0 0.1 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CdvA PF18822.1 ORY97531.1 - 0.85 9.5 11.7 0.25 11.2 1.8 3.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain CorA PF01544.18 ORY97531.1 - 4.3 6.6 7.8 10 5.3 7.8 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ATG16 PF08614.11 ORY97531.1 - 4.9 7.3 27.9 0.16 12.2 4.5 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 ORY97531.1 - 6.8 7.2 18.0 2.7 8.5 7.2 3.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 ORY97531.1 - 6.8 6.7 9.4 2.4 8.2 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 ORY97531.1 - 7.6 6.4 18.2 3.8 7.3 0.6 4.4 2 1 3 5 5 5 0 Septum formation initiator Annexin PF00191.20 ORY97533.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Annexin Pkinase PF00069.25 ORY97534.1 - 8.6e-79 264.6 0.0 1.3e-78 264.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97534.1 - 1.6e-40 139.0 0.0 2.5e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97534.1 - 1.1e-08 34.8 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY97534.1 - 0.00031 20.8 0.1 0.00082 19.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY97534.1 - 0.0086 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ntox14 PF15522.6 ORY97534.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 14 Haspin_kinase PF12330.8 ORY97534.1 - 0.014 14.4 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CHIP_TPR_N PF18391.1 ORY97534.1 - 0.021 15.6 0.3 3.2 8.6 0.0 2.9 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain RIO1 PF01163.22 ORY97534.1 - 0.034 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 ORY97534.1 - 0.045 13.4 1.4 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORY97534.1 - 0.07 11.9 0.0 0.07 11.9 0.0 1.9 3 0 0 3 3 3 0 Fungal protein kinase RAB3GAP2_N PF14655.6 ORY97534.1 - 0.23 10.7 1.3 0.41 9.9 1.3 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Metallophos_2 PF12850.7 ORY97535.1 - 1.2e-20 74.3 0.1 1.5e-20 74.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ORY97535.1 - 0.00022 21.8 3.1 0.28 11.7 0.4 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase RGS PF00615.19 ORY97537.1 - 5.8e-15 55.6 2.7 1.4e-14 54.4 2.7 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 ORY97537.1 - 0.0079 15.9 0.9 0.015 15.0 0.8 1.5 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain TIP120 PF08623.10 ORY97538.1 - 2.1e-41 141.5 1.4 2.1e-41 141.5 1.4 4.9 5 2 0 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 ORY97538.1 - 2.5e-15 56.6 7.0 0.0041 17.5 0.0 8.9 6 3 3 9 9 9 2 HEAT repeats HEAT PF02985.22 ORY97538.1 - 6.7e-11 41.5 13.4 0.44 10.9 0.0 10.4 12 0 0 12 12 8 3 HEAT repeat HEAT_EZ PF13513.6 ORY97538.1 - 7.6e-09 35.9 6.3 2 9.0 0.0 10.2 11 1 1 12 12 11 1 HEAT-like repeat CLASP_N PF12348.8 ORY97538.1 - 2.2e-05 24.1 10.7 1.7 8.2 0.1 6.4 3 1 1 5 5 5 1 CLASP N terminal Telomere_reg-2 PF10193.9 ORY97538.1 - 4.2e-05 23.9 8.6 0.0011 19.3 0.1 5.1 5 0 0 5 5 4 1 Telomere length regulation protein UME PF08064.13 ORY97538.1 - 0.0005 19.9 11.4 3.2 7.7 0.1 6.9 6 2 0 6 6 6 1 UME (NUC010) domain TAF6_C PF07571.13 ORY97538.1 - 0.0014 18.9 1.7 0.52 10.7 0.0 5.2 5 1 0 5 5 4 1 TAF6 C-terminal HEAT repeat domain Sec7_N PF12783.7 ORY97538.1 - 0.0047 16.8 18.3 0.13 12.2 0.4 7.1 4 2 4 8 8 8 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm PF00514.23 ORY97538.1 - 0.038 14.1 2.3 10 6.4 0.0 5.7 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat DUF4476 PF14771.6 ORY97538.1 - 0.048 14.0 0.1 0.28 11.5 0.0 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4476) Xpo1 PF08389.12 ORY97538.1 - 0.071 13.2 8.8 6.2 6.9 0.1 6.2 6 1 0 6 6 6 0 Exportin 1-like protein RNA_pol_3_Rpc31 PF11705.8 ORY97538.1 - 0.11 12.7 6.4 0.24 11.6 6.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1722 PF08349.11 ORY97538.1 - 0.16 12.2 0.7 11 6.4 0.1 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF1722) TAN PF11640.8 ORY97538.1 - 0.2 11.8 1.7 29 4.8 0.1 4.3 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair DUF4042 PF13251.6 ORY97538.1 - 0.24 11.1 2.7 21 4.8 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4042) ParcG PF10274.9 ORY97538.1 - 0.38 10.9 2.1 1.6e+02 2.3 0.0 4.8 5 1 0 5 5 5 0 Parkin co-regulated protein Cnd1 PF12717.7 ORY97538.1 - 0.46 10.5 14.8 3.9 7.5 0.2 6.2 7 1 0 7 7 5 0 non-SMC mitotic condensation complex subunit 1 PUL PF08324.11 ORY97538.1 - 0.46 9.7 9.0 2.6 7.2 0.0 4.7 3 2 2 5 5 5 0 PUL domain Sigma70_ner PF04546.13 ORY97538.1 - 1.3 8.8 7.9 0.69 9.8 4.8 2.2 2 0 0 2 2 1 0 Sigma-70, non-essential region BUD22 PF09073.10 ORY97538.1 - 2.9 7.1 4.5 6.5 6.0 4.5 1.5 1 0 0 1 1 1 0 BUD22 NopRA1 PF16201.5 ORY97538.1 - 3.2 7.3 6.3 72 2.9 0.0 5.4 5 2 0 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 Pox_RNA_Pol_19 PF05320.12 ORY97538.1 - 6.6 6.7 9.4 16 5.4 5.0 2.8 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.9 ORY97538.1 - 7.5 5.6 11.2 13 4.8 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CMAS PF02353.20 ORY97539.1 - 1.2e-63 214.9 0.5 1.5e-63 214.6 0.5 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY97539.1 - 4.3e-13 49.8 0.0 8.7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY97539.1 - 3.9e-11 43.5 0.0 7.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY97539.1 - 3.3e-09 36.8 0.0 6.5e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY97539.1 - 5e-08 33.6 0.0 8.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY97539.1 - 2.6e-06 27.3 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY97539.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 ORY97539.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 NodS PF05401.11 ORY97539.1 - 0.0036 16.9 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 ORY97539.1 - 0.0073 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ORY97539.1 - 0.063 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 ORY97539.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 ORY97539.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_L6 PF00347.23 ORY97540.1 - 6.6e-30 103.6 8.1 1.4e-18 67.4 4.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ZZ PF00569.17 ORY97541.1 - 9.9e-10 38.1 5.1 1.7e-09 37.4 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 ORY97541.1 - 5.8e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 ORY97541.1 - 0.011 16.0 4.7 0.021 15.2 4.7 1.4 1 0 0 1 1 1 0 C1 domain Myb_DNA-bind_6 PF13921.6 ORY97541.1 - 0.04 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain FHA PF00498.26 ORY97542.1 - 1.7e-15 57.1 0.0 2.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY97542.1 - 3.6e-13 49.0 5.5 6.6e-13 48.2 5.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY97542.1 - 1.5e-09 38.0 8.2 3e-09 37.1 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY97542.1 - 0.00013 21.9 8.6 0.00013 21.8 7.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY97542.1 - 0.00026 20.8 9.1 0.00044 20.1 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY97542.1 - 0.00048 20.3 7.5 0.0012 19.1 7.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain PHD PF00628.29 ORY97542.1 - 0.00051 19.9 4.8 0.00086 19.2 4.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.6 ORY97542.1 - 0.0011 18.8 11.0 0.0019 18.0 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 ORY97542.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 ORY97542.1 - 0.0076 16.3 3.9 0.015 15.3 3.9 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY97542.1 - 0.02 14.7 5.8 0.042 13.7 5.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY97542.1 - 0.04 13.9 5.0 0.04 13.9 5.0 1.7 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORY97542.1 - 5.9 6.6 7.8 1.3 8.7 4.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PRCC PF10253.9 ORY97543.1 - 1.8e-15 58.4 32.9 4.5e-14 53.7 32.9 2.2 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting SMAP PF15477.6 ORY97543.1 - 0.54 11.3 8.6 1.8 9.6 8.6 2.1 1 1 0 1 1 1 0 Small acidic protein family Adap_comp_sub PF00928.21 ORY97544.1 - 5.8e-95 317.6 0.1 7.7e-95 317.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY97544.1 - 1.5e-09 37.9 0.5 2.9e-09 37.0 0.5 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 ORY97544.1 - 0.023 13.8 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 Metallophos PF00149.28 ORY97545.1 - 6.1e-16 59.5 2.1 8.5e-16 59.1 2.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY97545.1 - 9.8e-06 25.9 2.0 1.5e-05 25.2 1.8 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORY97545.1 - 0.035 13.4 0.1 0.11 11.9 0.0 1.7 1 1 1 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Med9 PF07544.13 ORY97546.1 - 4.1e-10 39.6 2.2 4.8e-10 39.4 2.2 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CMD PF02627.20 ORY97547.1 - 0.016 15.3 0.0 0.1 12.7 0.0 2.1 2 1 0 2 2 2 0 Carboxymuconolactone decarboxylase family DUF3285 PF11688.8 ORY97548.1 - 0.33 10.9 1.7 1 9.3 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) DUF3040 PF11239.8 ORY97548.1 - 1 9.6 0.0 1 9.6 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) RPE65 PF03055.15 ORY97549.1 - 5e-92 309.5 0.0 6.7e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TPR_2 PF07719.17 ORY97550.1 - 2.9e-47 155.0 43.6 0.00082 19.3 0.0 18.5 18 0 0 18 18 18 10 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97550.1 - 3.5e-38 127.9 43.5 0.00042 20.0 0.2 18.0 19 1 0 19 19 18 8 Tetratricopeptide repeat TPR_8 PF13181.6 ORY97550.1 - 4e-29 98.4 26.6 0.037 14.2 0.1 15.7 16 0 0 16 16 16 8 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97550.1 - 2.7e-25 86.9 43.9 0.00021 21.8 0.0 18.5 11 4 10 21 21 19 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97550.1 - 3.9e-25 87.9 45.2 0.00065 19.9 0.0 13.8 11 4 4 15 15 14 8 Tetratricopeptide repeat TPR_11 PF13414.6 ORY97550.1 - 2.5e-22 78.3 13.2 0.0014 18.3 0.0 13.4 12 2 4 16 16 16 6 TPR repeat TPR_16 PF13432.6 ORY97550.1 - 1.1e-21 77.2 29.1 3.4e-05 24.4 0.0 10.0 8 3 2 11 11 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 ORY97550.1 - 8.1e-21 72.5 22.5 0.065 13.3 0.1 13.1 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORY97550.1 - 8e-18 63.5 19.4 0.46 11.0 0.0 14.0 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY97550.1 - 6.8e-17 61.7 29.7 0.024 15.1 0.0 10.4 9 1 3 12 12 10 7 Tetratricopeptide repeat TPR_9 PF13371.6 ORY97550.1 - 1.5e-09 37.8 17.6 0.081 13.1 0.0 8.4 7 2 2 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY97550.1 - 2.4e-07 30.9 23.5 0.0019 18.4 0.2 7.4 7 1 1 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORY97550.1 - 7.5e-06 25.6 28.2 0.55 10.2 0.2 10.5 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_22 PF18833.1 ORY97550.1 - 0.0004 20.5 0.0 0.0014 18.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3808 PF10300.9 ORY97550.1 - 0.0038 16.0 0.1 0.031 13.0 0.1 2.3 2 1 0 3 3 3 1 Protein of unknown function (DUF3808) TPR_6 PF13174.6 ORY97550.1 - 0.022 15.4 41.8 14 6.6 0.0 14.2 19 0 0 19 19 15 0 Tetratricopeptide repeat DUF4070 PF13282.6 ORY97550.1 - 0.029 14.5 0.0 32 4.6 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4070) Vps39_1 PF10366.9 ORY97550.1 - 0.073 13.4 0.3 8 6.8 0.0 3.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_4 PF07721.14 ORY97550.1 - 2.2 9.1 19.2 6.8 7.6 0.5 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Pmp3 PF01679.17 ORY97551.1 - 3.6e-24 84.7 9.4 4.1e-24 84.5 9.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF5614 PF18474.1 ORY97552.1 - 0.082 12.2 0.0 0.082 12.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5614) 14-3-3 PF00244.20 ORY97553.1 - 9e-106 352.4 3.6 1.1e-105 352.1 3.6 1.1 1 0 0 1 1 1 1 14-3-3 protein Cellulase PF00150.18 ORY97554.1 - 2.6e-11 43.5 6.1 1.5e-10 41.0 6.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sorb PF02208.16 ORY97554.1 - 0.063 13.1 0.1 0.46 10.4 0.1 2.4 2 0 0 2 2 2 0 Sorbin homologous domain Spectrin_like PF18373.1 ORY97554.1 - 0.071 13.2 0.5 6.6 6.9 0.0 3.0 3 0 0 3 3 3 0 Spectrin like domain AcetylCoA_hydro PF02550.15 ORY97555.1 - 2.3e-50 171.3 0.0 3.5e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 ORY97555.1 - 3.3e-40 137.6 0.0 4.8e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 ORY97555.1 - 0.0035 16.8 0.0 0.0085 15.5 0.0 1.6 2 0 0 2 2 2 1 Coenzyme A transferase CitF PF04223.12 ORY97555.1 - 0.0066 15.4 0.0 0.016 14.1 0.0 1.6 1 0 0 1 1 1 1 Citrate lyase, alpha subunit (CitF) FAM76 PF16046.5 ORY97556.1 - 0.004 16.6 3.1 0.004 16.6 3.1 4.4 1 1 2 4 4 4 1 FAM76 protein AAA_13 PF13166.6 ORY97556.1 - 0.0042 15.8 21.9 0.0042 15.8 21.9 3.8 1 1 0 3 3 3 1 AAA domain DUF4407 PF14362.6 ORY97556.1 - 2 7.7 86.1 0.13 11.6 16.2 5.1 1 1 3 5 5 5 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 ORY97556.1 - 3.7 7.3 113.6 0.096 12.5 29.3 5.8 3 1 2 5 5 5 0 Family with sequence similarity 184, A and B Pex24p PF06398.11 ORY97557.1 - 1.6e-18 66.8 5.6 3e-18 66.0 5.6 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.22 ORY97557.1 - 3.1e-10 39.8 5.9 3.1e-10 39.8 5.9 2.8 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 ORY97557.1 - 4.5 7.2 13.6 0.74 9.8 5.3 2.6 2 0 0 2 2 2 0 PHD-finger MARVEL PF01284.23 ORY97558.1 - 0.49 10.4 5.2 2.1 8.4 0.4 2.2 1 1 1 2 2 2 0 Membrane-associating domain DUF647 PF04884.14 ORY97559.1 - 2e-14 53.8 0.2 2.7e-14 53.4 0.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF647 PF04884.14 ORY97560.1 - 3.1e-28 99.0 0.0 3.9e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis CBF PF03914.17 ORY97561.1 - 0.031 14.3 0.0 0.033 14.2 0.0 1.0 1 0 0 1 1 1 0 CBF/Mak21 family HSF_DNA-bind PF00447.17 ORY97562.1 - 1.6e-30 105.6 0.1 3e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding YabA PF06156.13 ORY97562.1 - 0.019 15.6 0.8 0.042 14.5 0.8 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF4763 PF15960.5 ORY97562.1 - 0.02 14.2 0.6 0.03 13.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF29 PF01724.16 ORY97562.1 - 0.021 15.0 1.3 0.034 14.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF3439 PF11921.8 ORY97562.1 - 0.037 14.0 0.9 0.037 14.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF3597 PF12200.8 ORY97562.1 - 6.6 7.3 8.1 0.77 10.3 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) Rap_GAP PF02145.15 ORY97563.1 - 1.4e-20 73.7 0.0 2.8e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP RRM_1 PF00076.22 ORY97564.1 - 3.1e-12 46.1 0.3 5.2e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLH PF01738.18 ORY97565.1 - 2.4e-23 82.8 0.1 2.8e-23 82.6 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family HicB_lk_antitox PF15919.5 ORY97565.1 - 0.067 13.3 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system DLH PF01738.18 ORY97566.1 - 3e-24 85.8 0.1 3.4e-24 85.6 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORY97566.1 - 0.014 15.3 0.2 0.17 11.8 0.0 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ORY97566.1 - 0.05 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DAO PF01266.24 ORY97567.1 - 2.9e-41 142.2 0.0 3.9e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY97567.1 - 7.6e-09 35.7 0.0 3.4e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY97567.1 - 1.6e-05 24.3 0.0 0.076 12.2 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY97567.1 - 6.1e-05 23.0 0.1 0.016 15.2 0.0 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY97567.1 - 0.0013 17.5 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 ORY97567.1 - 0.0019 17.4 0.0 0.027 13.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY97567.1 - 0.0052 15.9 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ORY97567.1 - 0.023 14.0 0.1 0.066 12.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 ORY97567.1 - 0.034 14.7 0.0 0.17 12.5 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY97567.1 - 0.052 12.8 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORY97567.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 ORY97567.1 - 0.18 11.3 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MFS_1 PF07690.16 ORY97568.1 - 1.3e-47 162.5 20.5 1.3e-47 162.5 20.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY97568.1 - 9e-12 44.6 4.7 9e-12 44.6 4.7 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 ORY97568.1 - 0.0043 15.5 0.9 0.0043 15.5 0.9 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector Glug PF07581.12 ORY97568.1 - 0.028 14.8 1.1 0.11 12.9 1.1 2.1 1 0 0 1 1 1 0 The GLUG motif BT1 PF03092.16 ORY97568.1 - 0.075 11.3 4.5 0.04 12.2 0.2 2.2 2 0 0 2 2 2 0 BT1 family DUF5058 PF16481.5 ORY97568.1 - 0.092 12.4 0.1 0.092 12.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5058) BatA PF07584.11 ORY97568.1 - 0.14 12.6 0.0 0.14 12.6 0.0 2.6 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal TMEM208_SND2 PF05620.11 ORY97568.1 - 3.3 7.5 4.8 0.68 9.7 0.0 2.3 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 FA_desaturase PF00487.24 ORY97568.1 - 5.2 6.8 18.5 1.9 8.3 2.9 3.3 2 1 1 3 3 3 0 Fatty acid desaturase Cullin PF00888.22 ORY97569.1 - 8.9e-99 331.8 16.4 1.2e-98 331.4 16.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY97569.1 - 7.8e-10 38.6 0.2 5.9e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3658 PF12395.8 ORY97569.1 - 0.00044 20.1 0.3 0.0016 18.3 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function GP41 PF00517.17 ORY97569.1 - 0.44 10.4 4.9 0.5 10.2 0.1 2.7 3 0 0 3 3 3 0 Retroviral envelope protein RasGAP PF00616.19 ORY97569.1 - 0.75 9.5 5.2 0.53 10.0 0.4 2.8 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase CRM1_C PF08767.11 ORY97570.1 - 6e-125 416.7 5.5 6e-125 416.7 5.5 3.5 3 1 1 4 4 4 2 CRM1 C terminal Xpo1 PF08389.12 ORY97570.1 - 2.9e-40 137.8 14.1 4.7e-40 137.1 5.3 4.4 2 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 ORY97570.1 - 2e-32 110.6 3.7 1.1e-31 108.3 3.7 2.4 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 ORY97570.1 - 7.9e-30 102.7 2.8 7.9e-30 102.7 2.8 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 ORY97570.1 - 4e-20 71.0 1.5 8.5e-20 70.0 1.5 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 ORY97570.1 - 1.1e-12 47.7 0.0 4.4e-12 45.7 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 ORY97570.1 - 0.0032 17.4 0.0 0.16 11.9 0.1 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) PPR_2 PF13041.6 ORY97571.1 - 1.7e-08 34.5 0.0 3.3e-06 27.2 0.0 2.9 3 1 1 4 4 4 2 PPR repeat family PPR PF01535.20 ORY97571.1 - 1.5e-07 31.1 0.0 0.024 14.9 0.0 2.7 2 0 0 2 2 2 2 PPR repeat PPR_1 PF12854.7 ORY97571.1 - 0.0067 16.1 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 ORY97571.1 - 0.016 15.3 0.1 0.14 12.3 0.0 2.3 1 1 1 2 2 2 0 Pentatricopeptide repeat domain ComR_TPR PF18710.1 ORY97571.1 - 0.018 14.6 0.1 7.7 6.0 0.0 2.7 2 0 0 2 2 2 0 ComR tetratricopeptide SPOB_a PF14689.6 ORY97571.1 - 0.048 13.4 0.1 10 5.9 0.0 2.8 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_14 PF13428.6 ORY97571.1 - 0.34 11.8 1.9 50 5.1 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat GIDA PF01134.22 ORY97572.1 - 1.5e-149 498.4 0.0 2.4e-149 497.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 ORY97572.1 - 1.5e-71 240.9 0.2 2.3e-71 240.3 0.2 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 ORY97572.1 - 1.1e-06 28.3 0.9 2.3e-06 27.3 0.9 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY97572.1 - 2.1e-05 23.9 0.3 5.4e-05 22.6 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY97572.1 - 0.0002 20.2 1.0 0.014 14.2 0.4 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ORY97572.1 - 0.00027 20.1 2.4 0.0003 20.0 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY97572.1 - 0.0016 17.8 0.2 0.0036 16.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain COMP PF11598.8 ORY97572.1 - 2.1 8.9 4.0 6.9 7.2 0.1 3.0 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein BTG PF07742.12 ORY97573.1 - 0.13 12.2 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 BTG family LRR_8 PF13855.6 ORY97574.1 - 2.9e-14 52.5 10.7 5e-13 48.6 3.6 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY97574.1 - 3.3e-08 33.7 10.3 9.3e-07 29.1 0.4 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF2722 PF10846.8 ORY97574.1 - 0.0002 20.4 0.6 0.00021 20.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) LRR_6 PF13516.6 ORY97574.1 - 0.0064 16.4 13.9 0.17 12.0 0.3 3.9 4 0 0 4 4 3 2 Leucine Rich repeat LRR_1 PF00560.33 ORY97574.1 - 0.0091 16.4 16.1 0.23 12.1 0.1 5.1 4 1 1 5 5 3 2 Leucine Rich Repeat DUF4175 PF13779.6 ORY97574.1 - 0.013 13.4 9.1 0.017 13.1 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex26 PF07163.12 ORY97574.1 - 0.017 14.5 3.6 0.023 14.0 3.6 1.1 1 0 0 1 1 1 0 Pex26 protein Med3 PF11593.8 ORY97574.1 - 0.73 9.0 11.6 1.2 8.3 11.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 ORY97574.1 - 1.2 8.7 20.8 4.3 6.9 20.0 1.9 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 ORY97574.1 - 4 7.6 16.5 11 6.2 16.5 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2967 PF11179.8 ORY97574.1 - 4.4 5.3 9.3 5.8 4.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Redoxin PF08534.10 ORY97575.1 - 9.1e-31 106.5 0.0 1.1e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY97575.1 - 2.5e-11 43.6 0.0 3.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family O-FucT PF10250.9 ORY97576.1 - 2e-07 31.1 0.6 7.8e-05 22.5 0.3 3.1 2 2 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase XG_FTase PF03254.13 ORY97576.1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Cornichon PF03311.14 ORY97577.1 - 5.3e-51 172.1 15.2 6e-51 171.9 15.2 1.0 1 0 0 1 1 1 1 Cornichon protein PQ-loop PF04193.14 ORY97579.1 - 5.3e-39 131.8 16.0 2.2e-19 69.0 1.7 2.6 2 0 0 2 2 2 2 PQ loop repeat Vps39_2 PF10367.9 ORY97580.1 - 0.017 15.6 0.1 0.017 15.6 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 HECW1_helix PF18436.1 ORY97580.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Zn_clus PF00172.18 ORY97581.1 - 6.5e-12 45.4 8.4 9.3e-12 44.9 8.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VIR_N PF15912.5 ORY97581.1 - 0.044 13.4 4.6 0.057 13.0 4.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 ORY97581.1 - 0.29 10.6 5.3 0.38 10.2 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fungal_trans PF04082.18 ORY97582.1 - 3.9e-12 45.8 1.1 6.7e-12 45.0 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_20 PF00982.21 ORY97583.1 - 1.5e-196 653.7 0.0 1.8e-196 653.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY97583.1 - 5.6e-54 182.7 0.0 1e-53 181.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY97583.1 - 8.4e-05 22.4 0.0 0.00095 19.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.6 ORY97583.1 - 0.0004 20.8 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY97583.1 - 0.16 12.0 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Peptidase_C48 PF02902.19 ORY97584.1 - 4.1e-33 115.1 0.1 4.1e-33 115.1 0.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain FH2 PF02181.23 ORY97585.1 - 6.7e-90 301.9 8.9 1.3e-89 300.9 1.0 2.5 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORY97585.1 - 2.2e-09 37.2 0.0 2.2e-09 37.2 0.0 3.3 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORY97585.1 - 3.3e-08 33.4 0.0 3.3e-08 33.4 0.0 3.1 4 0 0 4 4 4 1 Diaphanous FH3 Domain DUF812 PF05667.11 ORY97585.1 - 0.0023 16.9 0.8 0.0023 16.9 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF812) EMP24_GP25L PF01105.24 ORY97585.1 - 0.021 14.8 2.6 2.9 7.8 1.2 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD 7TMR-HDED PF07697.11 ORY97585.1 - 0.04 14.0 1.9 3.5 7.7 0.0 2.8 2 0 0 2 2 2 0 7TM-HD extracellular Ribonuc_red_lgC PF02867.15 ORY97585.1 - 0.05 12.1 0.0 0.084 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain CENP-F_leu_zip PF10473.9 ORY97585.1 - 0.057 13.4 12.3 0.025 14.6 7.6 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FANCI_HD2 PF14680.6 ORY97585.1 - 0.067 12.4 1.1 0.15 11.3 1.1 1.5 1 0 0 1 1 1 0 FANCI helical domain 2 DUF1664 PF07889.12 ORY97585.1 - 0.12 12.4 4.9 1.9 8.6 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 ORY97585.1 - 1.4 8.8 9.8 4.7 7.1 4.6 3.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain PRP9_N PF16958.5 ORY97585.1 - 2.1 8.4 8.9 0.54 10.3 2.2 3.4 3 1 0 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus WXG100 PF06013.12 ORY97585.1 - 2.4 8.4 6.3 14 6.0 0.0 4.2 4 0 0 4 4 3 0 Proteins of 100 residues with WXG DUF948 PF06103.11 ORY97585.1 - 2.5 8.4 4.4 7.9 6.8 0.3 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 ORY97585.1 - 3.1 6.3 5.9 7.3 5.1 4.0 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Syntaxin_2 PF14523.6 ORY97585.1 - 7 7.1 7.9 2.9 8.3 2.0 3.3 2 1 1 3 3 3 0 Syntaxin-like protein FA_desaturase PF00487.24 ORY97586.1 - 4.1e-26 92.3 11.2 6.4e-26 91.7 11.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 ORY97586.1 - 1.2e-09 37.5 0.5 2.6e-09 36.4 0.5 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ras PF00071.22 ORY97588.1 - 9.2e-22 77.4 0.0 1.1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY97588.1 - 2.3e-09 37.5 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY97588.1 - 0.021 14.3 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family GHMP_kinases_N PF00288.26 ORY97589.1 - 1.6e-15 57.1 2.1 1.6e-15 57.1 2.1 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY97589.1 - 8.9e-06 26.0 0.1 2.1e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 ORY97589.1 - 0.0093 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature TPR_2 PF07719.17 ORY97590.1 - 2e-22 77.4 9.2 0.029 14.5 0.0 11.7 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97590.1 - 2.4e-18 65.1 13.4 0.23 11.4 0.0 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY97590.1 - 1.3e-17 64.2 0.3 0.054 14.2 0.0 7.4 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY97590.1 - 6.7e-16 58.6 9.1 0.00012 22.5 0.0 8.0 8 1 2 10 10 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY97590.1 - 3.1e-12 45.7 17.3 0.071 13.4 0.1 10.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97590.1 - 9.4e-12 45.1 11.7 0.014 15.6 0.2 8.1 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY97590.1 - 2.2e-11 42.9 6.9 0.041 13.9 0.3 9.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97590.1 - 2.3e-11 43.5 9.7 0.94 10.5 0.1 10.0 7 3 3 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY97590.1 - 6.7e-11 42.1 15.0 0.25 12.1 0.0 10.4 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY97590.1 - 1.7e-09 37.4 6.6 0.55 10.7 0.0 7.4 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_20 PF14561.6 ORY97590.1 - 6.6e-07 29.6 9.4 0.0075 16.6 0.4 6.3 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY97590.1 - 8.1e-07 28.6 4.1 0.048 13.3 0.2 5.7 7 0 0 7 7 7 2 TPR repeat DUF4919 PF16266.5 ORY97590.1 - 9.6e-06 25.7 0.2 0.5 10.3 0.1 4.3 2 1 2 4 4 4 1 Domain of unknown function (DUF4919) TPR_9 PF13371.6 ORY97590.1 - 1.7e-05 24.9 1.8 0.77 10.0 0.0 5.9 3 2 2 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY97590.1 - 2.6e-05 23.6 2.4 0.19 10.9 0.1 3.7 3 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY97590.1 - 0.029 14.6 8.1 1.7 8.9 0.3 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY97590.1 - 0.052 14.2 1.6 4 8.3 0.1 4.4 5 0 0 5 5 2 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY97590.1 - 0.18 12.1 12.3 1.7 9.0 0.3 5.4 4 2 3 7 7 6 0 Vacuolar sorting protein 39 domain 1 TPR_10 PF13374.6 ORY97590.1 - 0.38 10.7 19.2 1.6 8.7 0.1 7.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Na_Ca_ex PF01699.24 ORY97591.1 - 7.8e-35 120.1 33.7 1.6e-17 63.9 13.8 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Creatinase_N_2 PF16189.5 ORY97592.1 - 3.9e-51 173.3 0.2 1.7e-50 171.3 0.2 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ORY97592.1 - 3e-45 154.5 0.0 4.2e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 ORY97592.1 - 2.7e-22 78.6 0.0 1e-21 76.7 0.0 2.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ORY97592.1 - 2.1e-20 73.7 0.0 7.9e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain SH3_1 PF00018.28 ORY97593.1 - 3.4e-40 135.4 5.7 1.9e-13 49.8 0.1 3.6 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 ORY97593.1 - 7.6e-39 131.3 7.0 1.3e-13 50.6 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 ORY97593.1 - 2.9e-33 113.5 0.0 7.4e-33 112.2 0.0 1.7 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 ORY97593.1 - 1.8e-27 94.8 0.0 1.3e-08 34.3 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_10 PF17902.1 ORY97593.1 - 2.5e-06 27.4 0.2 0.13 12.3 0.0 4.0 4 0 0 4 4 4 2 SH3 domain SH3_3 PF08239.11 ORY97593.1 - 0.0051 17.1 3.1 0.89 9.9 0.0 2.8 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 ORY97593.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_6 PF15406.6 ORY97593.1 - 0.056 13.7 0.2 0.056 13.7 0.2 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2151 PF10221.9 ORY97593.1 - 5.3 5.5 12.4 13 4.2 0.1 3.4 3 0 0 3 3 3 0 Cell cycle and development regulator MFS_1 PF07690.16 ORY97594.1 - 5.4e-33 114.4 30.9 6e-33 114.2 30.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_11 PF13720.6 ORY97595.1 - 0.097 13.1 0.4 0.44 11.1 0.2 2.1 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FAD_SOX PF18371.1 ORY97595.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Lipase_GDSL_2 PF13472.6 ORY97596.1 - 5.7e-06 26.8 0.1 1.3e-05 25.7 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY97596.1 - 0.0077 16.2 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase 3HCDH_RFF PF18321.1 ORY97596.1 - 0.04 14.3 0.2 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Alk_phosphatase PF00245.20 ORY97598.1 - 4.1e-87 292.8 0.0 4.2e-48 164.3 0.1 2.1 1 1 1 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.18 ORY97598.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PH PF00169.29 ORY97599.1 - 4.2e-13 49.7 0.0 7.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY97599.1 - 0.034 14.6 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PAS_3 PF08447.12 ORY97600.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 ORY97600.1 - 0.00033 20.7 11.3 0.00053 20.1 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDP_Man_Dehyd PF16363.5 ORY97601.1 - 3e-161 536.4 0.0 3.4e-161 536.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY97601.1 - 2.6e-75 253.0 0.0 3.4e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY97601.1 - 3.6e-07 29.6 0.0 5.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY97601.1 - 3.5e-05 23.1 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY97601.1 - 0.0004 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family EMG1 PF03587.14 ORY97602.1 - 1.4e-77 259.7 0.0 1.7e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ank_2 PF12796.7 ORY97603.1 - 2.5e-10 40.8 0.5 9.5e-07 29.3 0.2 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY97603.1 - 2.3e-06 28.0 0.4 0.00011 22.7 0.2 3.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY97603.1 - 4.7e-05 23.5 0.7 0.72 10.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY97603.1 - 0.00016 21.9 2.2 0.0032 17.8 0.1 3.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY97603.1 - 0.001 19.4 0.7 0.062 13.8 0.3 3.3 3 1 0 3 3 3 1 Ankyrin repeat Sin3a_C PF16879.5 ORY97604.1 - 1.2e-57 195.8 13.4 4.9e-57 193.8 10.7 2.7 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY97604.1 - 4.9e-46 154.6 7.6 2.5e-17 62.7 0.0 4.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY97604.1 - 5.9e-38 128.9 0.8 1.9e-37 127.2 0.8 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor PARM PF17061.5 ORY97604.1 - 6.8 6.7 25.8 18 5.4 25.8 1.7 1 0 0 1 1 1 0 PARM Barwin PF00967.17 ORY97606.1 - 5.1e-07 29.6 0.8 7.4e-07 29.0 0.8 1.4 1 1 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 ORY97606.1 - 6.5e-05 23.1 0.2 0.00013 22.2 0.0 1.6 2 0 0 2 2 2 1 Lytic transglycolase DUF3808 PF10300.9 ORY97607.1 - 4.3e-63 213.7 2.0 1.4e-62 212.0 1.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 ORY97607.1 - 0.0015 18.5 1.6 12 6.3 0.4 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97607.1 - 0.0033 17.7 0.8 0.2 12.0 0.0 3.9 5 1 0 5 5 5 1 Tetratricopeptide repeat dsrm PF00035.26 ORY97608.1 - 1.4e-11 44.9 0.1 9.8e-08 32.6 0.1 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 ORY97608.1 - 1.5e-05 25.1 1.1 0.031 14.5 0.0 3.5 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 ORY97608.1 - 5.2e-05 23.3 0.2 0.055 13.6 0.0 3.4 3 0 0 3 3 3 1 Dicer dimerisation domain Tab2_like PF06485.11 ORY97608.1 - 0.017 14.7 0.7 0.026 14.0 0.7 1.2 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Peptidase_C12 PF01088.21 ORY97609.1 - 1.8e-59 201.0 0.0 2.1e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Polysacc_deac_1 PF01522.21 ORY97610.1 - 4.9e-35 120.1 0.0 1.1e-34 119.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY97610.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 nec1 PF10379.9 ORY97610.1 - 0.17 11.3 0.0 0.17 11.3 0.0 2.9 2 2 2 4 4 4 0 Virulence protein nec1 COMP PF11598.8 ORY97611.1 - 0.028 14.9 0.3 0.061 13.8 0.2 1.6 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein Biotin_lipoyl PF00364.22 ORY97612.1 - 4.2e-21 74.5 0.2 1e-19 70.1 0.0 2.6 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY97612.1 - 1.3e-08 35.0 0.2 3.1e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ORY97612.1 - 3.6e-05 23.5 0.3 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like 2-oxoacid_dh PF00198.23 ORY97612.1 - 0.00011 21.8 0.1 0.0079 15.7 0.0 2.2 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HlyD_3 PF13437.6 ORY97612.1 - 0.0072 17.0 0.4 0.031 15.0 0.1 2.3 2 1 0 2 2 2 1 HlyD family secretion protein QRPTase_N PF02749.16 ORY97612.1 - 0.093 12.8 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Pmp3 PF01679.17 ORY97613.1 - 9.3e-24 83.4 4.4 1.1e-23 83.2 4.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator F-box-like PF12937.7 ORY97614.1 - 0.00091 19.1 1.7 0.00091 19.1 1.7 2.1 2 0 0 2 2 2 1 F-box-like Pyrophosphatase PF00719.19 ORY97615.1 - 9.7e-35 119.7 0.0 1.1e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 Inorganic pyrophosphatase Sugar_tr PF00083.24 ORY97616.1 - 3.2e-108 362.5 16.5 3.8e-108 362.3 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY97616.1 - 1.6e-33 116.1 35.3 4.6e-24 85.0 10.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY97616.1 - 5.3e-05 21.8 0.4 5.3e-05 21.8 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) RNase_T PF00929.24 ORY97617.1 - 7.3e-40 137.2 0.0 8.4e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ORY97617.1 - 5.6e-05 23.2 0.0 7.5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like UPF0176_N PF17773.1 ORY97617.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain Kinesin PF00225.23 ORY97618.1 - 1.8e-91 306.5 0.0 3.5e-91 305.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY97618.1 - 1.1e-14 54.6 1.7 9.1e-13 48.4 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding DUF3138 PF11336.8 ORY97618.1 - 0.16 10.6 6.0 1.7 7.1 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DivIC PF04977.15 ORY97618.1 - 0.98 9.2 17.3 0.75 9.6 0.8 4.0 3 1 1 4 4 4 0 Septum formation initiator FapA PF03961.13 ORY97618.1 - 1.5 7.3 9.4 21 3.6 8.5 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A AbiH PF14253.6 ORY97618.1 - 6.1 6.6 7.5 13 5.5 7.5 1.6 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH SBP PF03110.14 ORY97619.1 - 0.027 14.8 0.7 0.04 14.2 0.7 1.3 1 0 0 1 1 1 0 SBP domain MFS_1 PF07690.16 ORY97621.1 - 6.5e-50 170.0 38.9 6.5e-50 170.0 38.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY97621.1 - 6.8e-16 58.2 5.7 6.8e-16 58.2 5.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY97621.1 - 9.4e-12 44.1 9.7 9.4e-12 44.1 9.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SE PF08491.10 ORY97621.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pkinase PF00069.25 ORY97622.1 - 4.3e-52 177.1 0.0 6.2e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97622.1 - 8.1e-27 94.1 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97622.1 - 3.3e-05 23.4 0.0 9.7e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY97622.1 - 0.00012 22.1 0.1 0.0047 16.9 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY97622.1 - 0.00029 19.9 0.0 0.00048 19.2 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 ORY97622.1 - 0.00055 19.0 0.0 0.00098 18.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY97622.1 - 0.004 16.8 0.0 0.75 9.4 0.0 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY97622.1 - 0.086 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sarcoglycan_1 PF04790.13 ORY97623.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Hist_deacetyl PF00850.19 ORY97625.1 - 5e-84 282.4 0.0 8.4e-84 281.6 0.0 1.3 2 0 0 2 2 2 1 Histone deacetylase domain Zn_clus PF00172.18 ORY97627.1 - 9.4e-12 44.9 4.0 1.2e-11 44.5 4.0 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY97628.1 - 4.1e-41 140.8 0.0 4.3e-40 137.4 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spt20 PF12090.8 ORY97628.1 - 2.4 7.7 9.6 3.8 7.0 9.6 1.3 1 0 0 1 1 1 0 Spt20 family Robl_LC7 PF03259.17 ORY97629.1 - 7.4e-10 38.5 0.2 1.2e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain MAPKK1_Int PF08923.10 ORY97629.1 - 0.1 12.4 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting JmjC PF02373.22 ORY97630.1 - 2.3e-15 57.0 0.0 5.7e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 ORY97630.1 - 0.00021 21.1 0.0 0.0041 16.9 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain Zn_Tnp_IS91 PF14319.6 ORY97630.1 - 0.038 14.0 3.2 0.043 13.8 0.5 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain TFIIF_alpha PF05793.12 ORY97631.1 - 1.3e-27 96.7 47.5 2.4e-17 62.7 6.6 3.0 2 1 1 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ubiquitin PF00240.23 ORY97632.1 - 2.7e-08 33.4 0.0 5.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 ORY97632.1 - 3.1e-06 27.7 0.2 1.5e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY97632.1 - 1.2e-05 25.4 0.0 1.2e-05 25.4 0.0 2.2 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 ORY97632.1 - 0.048 13.5 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TFIIA PF03153.13 ORY97632.1 - 2.3 8.1 36.9 4.2 7.3 36.1 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 ORY97632.1 - 7.1 5.2 19.3 4.2 5.9 2.0 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SpoIIE PF07228.12 ORY97633.1 - 2.1e-13 50.6 0.0 3.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ORY97633.1 - 1.8e-05 24.5 0.0 4.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 ORY97633.1 - 0.039 13.6 0.1 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C SRF-TF PF00319.18 ORY97636.1 - 6.7e-21 73.5 0.1 1.1e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Trp_syntA PF00290.20 ORY97637.1 - 9e-90 300.0 0.0 2.2e-89 298.7 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 ORY97637.1 - 6.2e-49 167.0 0.6 9.8e-49 166.3 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 ORY97637.1 - 0.0024 17.4 0.1 0.0069 15.9 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein Med13_C PF06333.12 ORY97638.1 - 2e-42 145.6 2.3 2e-42 145.6 2.3 3.5 3 2 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 ORY97638.1 - 3.5e-20 72.8 11.1 3.4e-11 43.4 0.1 3.4 3 1 0 4 4 4 2 MID domain of medPIWI Med13_N PF11597.8 ORY97638.1 - 2.4e-08 33.8 0.6 2.4e-08 33.8 0.6 2.2 3 0 0 3 3 3 1 Mediator complex subunit 13 N-terminal Nop14 PF04147.12 ORY97638.1 - 0.38 8.9 6.2 0.6 8.3 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 ORY97638.1 - 0.7 7.9 10.2 0.99 7.4 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 ORY97638.1 - 3.9 5.6 7.8 6.4 4.9 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein B56 PF01603.20 ORY97639.1 - 6.9e-183 608.3 0.2 6.9e-183 608.3 0.2 1.6 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 ORY97639.1 - 0.082 12.8 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal MFS_1 PF07690.16 ORY97640.1 - 3.8e-37 128.1 25.6 3.8e-37 128.1 25.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY97640.1 - 1.5e-05 24.4 9.0 1.5e-05 24.4 9.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Herpes_US9 PF06072.11 ORY97640.1 - 0.78 9.7 5.4 0.63 10.0 0.7 3.3 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 TMEM43 PF07787.12 ORY97640.1 - 2.8 7.2 7.9 0.38 10.1 0.1 3.0 3 0 0 3 3 3 0 Transmembrane protein 43 MFS_1 PF07690.16 ORY97641.1 - 9.4e-33 113.6 28.7 9.4e-33 113.6 28.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY97641.1 - 1.7e-06 27.6 3.1 1.7e-06 27.6 3.1 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ORY97641.1 - 2.5e-06 26.7 18.2 2.5e-06 26.7 18.2 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter DoxX_3 PF13781.6 ORY97641.1 - 0.64 10.7 18.3 0.51 11.0 2.6 3.1 3 0 0 3 3 3 0 DoxX-like family TMEMspv1-c74-12 PF11044.8 ORY97641.1 - 9.1 6.3 7.0 0.52 10.3 0.6 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein OATP PF03137.20 ORY97641.1 - 9.3 4.4 18.1 2.9 6.1 1.6 3.3 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 14-3-3 PF00244.20 ORY97642.1 - 3e-93 311.4 6.9 3.4e-93 311.2 6.9 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 ORY97642.1 - 0.013 15.5 0.1 0.046 13.7 0.1 1.9 1 0 0 1 1 1 0 Flagellar protein FlaF Ima1_N PF09779.9 ORY97642.1 - 0.073 13.9 0.2 2.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Ima1 N-terminal domain Sulfate_transp PF00916.20 ORY97643.1 - 4.8e-95 318.5 20.4 5.8e-95 318.2 20.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY97643.1 - 0.00017 21.2 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY97643.1 - 0.0017 18.7 3.0 0.0017 18.7 3.0 2.8 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF1304 PF06993.12 ORY97643.1 - 2.1 8.4 5.5 0.72 9.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) DUF2433 PF10360.9 ORY97644.1 - 3.1e-44 150.0 0.1 5.4e-44 149.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 ORY97644.1 - 3.4e-07 30.0 0.0 6.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 ORY97644.1 - 0.00042 20.9 0.0 0.00089 19.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY97644.1 - 0.0026 18.0 0.0 0.011 15.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pox_MCEL PF03291.16 ORY97645.1 - 4.8e-85 285.6 0.1 1.1e-84 284.5 0.1 1.5 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 ORY97645.1 - 6.9e-13 49.1 0.1 1.9e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY97645.1 - 2.5e-09 37.1 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY97645.1 - 1.8e-07 31.7 0.0 4.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY97645.1 - 4.8e-07 30.5 0.0 9.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY97645.1 - 4.4e-06 26.6 0.0 6.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Mesothelin PF06060.12 ORY97645.1 - 0.01 14.1 0.0 0.013 13.7 0.0 1.1 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) MetW PF07021.12 ORY97645.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NNMT_PNMT_TEMT PF01234.17 ORY97645.1 - 0.023 13.9 0.0 0.061 12.5 0.0 1.7 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 ORY97645.1 - 0.041 13.3 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 ORY97645.1 - 0.11 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ORY97645.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 ORY97646.1 - 2e-63 214.2 0.0 3.7e-63 213.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97646.1 - 1.7e-33 116.0 0.0 2.6e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 ORY97646.1 - 4.3e-16 58.5 30.1 1.4e-09 37.6 8.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 ORY97646.1 - 1.3e-11 44.4 16.8 1.2e-08 34.9 6.5 2.9 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 ORY97646.1 - 3.4e-09 37.3 0.4 3.2e-08 34.2 0.7 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 ORY97646.1 - 4.3e-06 27.0 0.0 8.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 ORY97646.1 - 0.0002 20.4 0.2 0.00034 19.7 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY97646.1 - 0.0011 18.6 1.6 1.7 8.2 0.0 2.9 2 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORY97646.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORY97646.1 - 0.073 13.0 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ax_dynein_light PF10211.9 ORY97646.1 - 2.4 8.1 9.5 0.085 12.8 1.5 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Uds1 PF15456.6 ORY97646.1 - 3.7 7.7 10.9 4.7 7.4 2.2 3.1 3 0 0 3 3 3 0 Up-regulated During Septation OMPdecase PF00215.24 ORY97647.1 - 1.9e-77 259.9 0.1 2.2e-77 259.6 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF1940 PF09155.10 ORY97647.1 - 0.024 14.7 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Dus PF01207.17 ORY97647.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) MFS_1 PF07690.16 ORY97648.1 - 1.1e-54 185.8 30.1 3.3e-53 180.9 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY97648.1 - 5.2e-15 55.2 5.0 5.2e-15 55.2 5.0 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORY97648.1 - 0.00034 19.2 7.1 0.00057 18.4 7.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORY97648.1 - 0.001 17.5 10.9 0.02 13.2 3.6 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 ORY97648.1 - 0.17 10.2 11.3 0.041 12.3 5.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector PALP PF00291.25 ORY97649.1 - 1.1e-68 231.9 0.1 1.4e-68 231.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORY97649.1 - 2.6e-13 50.2 0.1 2.7e-06 27.7 0.0 3.4 3 1 1 4 4 4 2 CBS domain Glyco_tran_WecB PF03808.13 ORY97649.1 - 0.058 13.3 0.0 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF5333 PF17267.2 ORY97649.1 - 0.13 12.4 0.3 2.7 8.2 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5333) Methyltransf_12 PF08242.12 ORY97649.1 - 0.14 12.9 0.0 0.69 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 ORY97650.1 - 9e-62 208.8 0.0 8e-35 120.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97650.1 - 1.2e-39 136.1 0.1 6.2e-25 87.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY97650.1 - 6.9e-06 25.6 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORY97650.1 - 0.00068 18.5 0.3 0.0024 16.7 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY97650.1 - 0.04 12.8 0.0 0.091 11.7 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY97650.1 - 0.097 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tir_receptor_C PF07489.11 ORY97650.1 - 0.23 11.4 4.1 0.48 10.3 2.7 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus SRP-alpha_N PF04086.13 ORY97651.1 - 6.3 6.6 12.3 7.4 6.4 12.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Yippee-Mis18 PF03226.14 ORY97652.1 - 2.4e-13 50.2 0.1 2.9e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cytochrome_C7 PF14522.6 ORY97652.1 - 0.0057 16.6 0.6 0.027 14.4 0.7 1.9 1 1 1 2 2 2 1 Cytochrome c7 and related cytochrome c SelR PF01641.18 ORY97652.1 - 0.0091 16.1 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 1 SelR domain zf-CHY PF05495.12 ORY97652.1 - 0.017 15.6 0.5 0.43 11.1 0.1 2.1 2 0 0 2 2 2 0 CHY zinc finger CCP_MauG PF03150.14 ORY97652.1 - 0.055 14.1 0.8 3.9 8.1 0.2 2.1 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Cytochrom_c3_2 PF14537.6 ORY97652.1 - 0.064 13.7 0.8 1.8 9.1 0.8 2.2 1 1 0 1 1 1 0 Cytochrome c3 RIG-I_C-RD PF11648.8 ORY97652.1 - 0.069 13.4 0.1 0.098 12.9 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I DUF678 PF05077.12 ORY97652.1 - 0.083 13.0 1.3 0.54 10.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF678) Abhydrolase_3 PF07859.13 ORY97653.1 - 8e-27 94.5 0.0 1.2e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY97653.1 - 2.8e-07 29.8 0.0 1.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORY97653.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family AFG1_ATPase PF03969.16 ORY97653.1 - 0.013 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase STIMATE PF12400.8 ORY97654.1 - 5e-39 133.7 7.2 9.5e-39 132.8 7.2 1.4 1 0 0 1 1 1 1 STIMATE family Sugar_tr PF00083.24 ORY97656.1 - 8.3e-44 150.2 26.7 9.5e-26 90.6 8.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY97656.1 - 3.4e-17 62.4 62.4 6.8e-15 54.8 35.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY97656.1 - 0.0016 17.1 16.6 0.0066 15.1 0.1 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein Mito_carr PF00153.27 ORY97657.1 - 1.1e-24 86.2 0.0 3.4e-09 36.5 0.0 4.5 4 1 0 4 4 4 4 Mitochondrial carrier protein BAR PF03114.18 ORY97659.1 - 3.2e-34 118.6 7.8 4e-34 118.3 7.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY97659.1 - 6.7e-17 60.8 0.1 1.2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY97659.1 - 1.5e-15 56.8 0.1 2.6e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY97659.1 - 9.3e-09 34.8 0.0 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 ORY97659.1 - 2.1e-05 23.8 2.0 3.3e-05 23.2 2.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking YscO-like PF16789.5 ORY97659.1 - 1.4 8.9 14.2 0.077 13.0 9.0 1.5 2 0 0 2 2 2 0 YscO-like protein UPF0242 PF06785.11 ORY97659.1 - 6.3 6.9 14.0 0.46 10.6 8.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_hydro81C PF17652.1 ORY97660.1 - 6.8e-74 249.2 1.4 1.4e-55 189.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 ORY97660.1 - 1.5e-61 208.3 0.3 2.1e-61 207.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain LRR_8 PF13855.6 ORY97661.1 - 5.4e-21 74.1 31.5 1.2e-09 37.8 5.2 3.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY97661.1 - 3.3e-14 52.8 14.2 3.9e-06 27.1 3.8 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY97661.1 - 0.0001 22.3 10.5 4.4 8.2 0.2 5.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 ORY97661.1 - 0.0009 18.8 4.6 0.0014 18.1 2.8 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 ORY97661.1 - 0.22 11.7 13.2 1.1 9.5 0.5 5.0 5 0 0 5 5 5 0 Leucine Rich repeat AAA_11 PF13086.6 ORY97662.1 - 6.8e-11 42.4 2.1 6.8e-09 35.9 2.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORY97662.1 - 1.9e-07 30.9 0.0 5.6e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY97662.1 - 2.5e-07 30.6 3.7 6.4e-06 26.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 ORY97662.1 - 7.2e-07 29.7 0.0 0.0022 18.4 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY97662.1 - 1.1e-06 29.0 1.0 0.0012 19.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 ORY97662.1 - 6e-06 26.7 2.0 0.00043 20.7 0.2 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 ORY97662.1 - 1.1e-05 25.8 0.1 0.094 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 ORY97662.1 - 8e-05 22.2 0.0 0.00076 19.0 0.0 2.4 3 0 0 3 3 3 1 PhoH-like protein ResIII PF04851.15 ORY97662.1 - 9e-05 22.5 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 ORY97662.1 - 0.00029 20.2 0.0 0.69 9.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 ORY97662.1 - 0.0053 16.7 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 ORY97662.1 - 0.013 15.7 0.0 0.042 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY97662.1 - 0.061 12.4 0.3 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 ORY97662.1 - 0.069 13.1 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY97662.1 - 0.092 13.1 0.0 0.51 10.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 ORY97662.1 - 0.12 12.0 0.1 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY97662.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ORY97662.1 - 0.17 11.8 0.0 0.49 10.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Helicase_RecD PF05127.14 ORY97662.1 - 0.21 11.4 0.7 8.9 6.1 0.0 2.7 2 0 0 2 2 2 0 Helicase DUF1690 PF07956.11 ORY97663.1 - 8.8e-11 42.4 1.0 1e-10 42.2 1.0 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) ARGLU PF15346.6 ORY97663.1 - 0.25 11.2 8.8 0.23 11.3 4.0 2.0 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 CHCH PF06747.13 ORY97664.1 - 1.9e-06 27.8 4.9 1.9e-06 27.8 4.9 2.5 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 ORY97664.1 - 5.2e-06 26.4 11.2 0.00047 20.1 4.1 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 ORY97664.1 - 0.29 11.2 10.5 0.76 9.8 3.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Acetyltransf_1 PF00583.25 ORY97665.1 - 3.5e-19 69.2 0.0 4.3e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY97665.1 - 1.3e-11 44.6 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY97665.1 - 1.8e-11 44.3 0.0 2.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY97665.1 - 2.1e-07 30.8 0.1 3.2e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ORY97665.1 - 5.4e-05 23.4 0.0 6.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY97665.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY97665.1 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY97665.1 - 0.0022 18.7 0.0 0.0026 18.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mrr_cat PF04471.12 ORY97665.1 - 0.11 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Rhomboid PF01694.22 ORY97666.1 - 2.2e-31 108.9 8.4 2.9e-31 108.5 8.4 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 ORY97666.1 - 0.00036 21.0 0.0 0.00064 20.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Trep_Strep PF09605.10 ORY97666.1 - 0.0076 16.2 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4010 PF13194.6 ORY97666.1 - 0.029 14.0 1.8 0.03 14.0 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4010) Sec10 PF07393.11 ORY97667.1 - 5.3e-194 646.6 0.2 5.3e-194 646.6 0.2 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec10 SCF PF02404.15 ORY97667.1 - 0.016 14.6 0.6 1.3 8.3 0.2 2.7 2 0 0 2 2 2 0 Stem cell factor DUF4649 PF15507.6 ORY97667.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Occludin_ELL PF07303.13 ORY97667.1 - 0.097 13.4 1.2 1.5 9.6 0.0 3.2 2 1 1 3 3 3 0 Occludin homology domain UQ_con PF00179.26 ORY97669.1 - 6.6e-50 168.4 0.0 7.5e-50 168.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CTP_transf_like PF01467.26 ORY97671.1 - 1.3e-30 106.5 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Aminotran_1_2 PF00155.21 ORY97673.1 - 1.4e-59 202.1 0.0 1.7e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY97673.1 - 0.00097 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 ORY97673.1 - 0.022 13.5 0.0 0.048 12.4 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain CYYR1 PF10873.8 ORY97673.1 - 0.45 10.9 1.7 0.93 9.9 1.7 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 MatE PF01554.18 ORY97674.1 - 1.8e-59 200.0 31.2 1.1e-32 112.9 9.4 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 ORY97674.1 - 1.9e-05 24.7 12.0 1.9e-05 24.7 12.0 4.4 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain E1-E2_ATPase PF00122.20 ORY97674.1 - 0.069 12.7 1.7 3.6 7.1 0.1 3.4 2 1 1 3 3 3 0 E1-E2 ATPase DUF378 PF04070.12 ORY97674.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF378) AA_permease_2 PF13520.6 ORY97675.1 - 4.8e-64 216.7 50.5 5.9e-64 216.5 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY97675.1 - 8.3e-24 84.0 43.1 1.1e-23 83.6 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 ORY97676.1 - 1e-30 106.7 0.3 2.1e-30 105.7 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY97676.1 - 1.6e-05 24.9 17.3 3.1e-05 24.0 17.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NADH_4Fe-4S PF10589.9 ORY97676.1 - 0.081 13.0 4.1 0.2 11.8 4.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Mito_carr PF00153.27 ORY97677.1 - 5.8e-43 144.7 8.1 6.9e-16 58.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BING4CT PF08149.11 ORY97678.1 - 5.5e-42 141.5 0.1 1.1e-38 130.9 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 ORY97678.1 - 1.6e-10 41.4 0.1 0.00033 21.4 0.0 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY97678.1 - 4.8e-09 36.4 0.0 0.63 10.4 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY97678.1 - 0.00044 19.9 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.14 ORY97678.1 - 0.00045 19.4 0.0 0.00085 18.5 0.0 1.4 1 1 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 ORY97678.1 - 0.0033 16.8 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain Perilipin PF03036.16 ORY97679.1 - 3.1e-10 39.7 15.7 4.5e-08 32.5 0.2 3.3 1 1 2 3 3 3 3 Perilipin family SOR_SNZ PF01680.17 ORY97679.1 - 0.051 13.4 0.2 0.17 11.6 0.1 1.8 1 1 1 2 2 2 0 SOR/SNZ family SesA PF17107.5 ORY97679.1 - 0.088 13.0 3.6 8.2 6.6 0.6 3.3 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Kelch_4 PF13418.6 ORY97680.1 - 1.4e-43 146.6 16.2 1e-09 38.2 0.1 6.3 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY97680.1 - 5.8e-43 144.3 10.3 7.8e-10 38.5 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 ORY97680.1 - 2.8e-39 132.4 12.6 1.5e-06 27.7 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 ORY97680.1 - 2.9e-38 129.4 12.6 2.5e-07 30.8 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY97680.1 - 3.7e-35 119.1 9.1 1e-06 28.8 0.0 6.2 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 ORY97680.1 - 1.1e-27 94.9 8.6 0.00068 19.5 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Asp PF00026.23 ORY97680.1 - 0.18 11.2 0.5 84 2.4 0.0 3.5 4 0 0 4 4 4 0 Eukaryotic aspartyl protease DEAD PF00270.29 ORY97681.1 - 4.4e-50 169.9 0.0 8.3e-50 169.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY97681.1 - 1.7e-31 108.8 0.1 1.3e-30 106.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY97681.1 - 5.1e-08 33.1 0.1 3.9e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY97681.1 - 2.9e-06 26.7 0.4 6e-06 25.6 0.4 1.6 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 ORY97681.1 - 0.045 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 SWI2/SNF2 ATPase WH2 PF02205.20 ORY97682.1 - 1.4e-07 31.1 1.7 2.9e-07 30.1 0.5 2.1 2 0 0 2 2 2 1 WH2 motif 6PF2K PF01591.18 ORY97683.1 - 6.4e-78 261.1 0.2 8.5e-78 260.7 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY97683.1 - 4e-36 124.5 0.0 6.8e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY97683.1 - 1.5e-05 25.2 0.0 3.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORY97683.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 ORY97683.1 - 0.0027 17.0 0.1 0.0091 15.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin Elongin_A PF06881.11 ORY97684.1 - 2.4e-26 92.3 2.4 2.4e-26 92.3 2.4 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A NPA PF16469.5 ORY97684.1 - 0.033 14.7 0.1 0.057 14.0 0.1 1.3 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Arnt_C PF18583.1 ORY97684.1 - 0.092 12.4 0.3 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain DUF4407 PF14362.6 ORY97684.1 - 0.13 11.6 1.3 0.17 11.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADH_zinc_N PF00107.26 ORY97685.1 - 3e-20 72.5 0.0 5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY97685.1 - 4.4e-09 37.5 0.0 1.3e-08 36.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY97685.1 - 1.1e-07 31.6 0.0 2.7e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 ORY97685.1 - 0.00029 20.9 0.1 0.061 13.5 0.0 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.21 ORY97685.1 - 0.01 15.2 0.5 0.017 14.5 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Chitin_synth_2 PF03142.15 ORY97686.1 - 1.7e-238 792.6 0.1 2.5e-238 792.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 ORY97686.1 - 1.6e-14 53.8 0.6 8.1e-11 41.9 0.1 3.3 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 ORY97686.1 - 3.6e-14 53.2 0.1 1e-12 48.5 0.0 2.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY97686.1 - 3.1e-11 43.6 3.9 3.1e-11 43.6 3.9 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Myosin_head PF00063.21 ORY97686.1 - 2.1e-07 29.6 0.0 3.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 ORY97686.1 - 0.00011 22.0 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-H2C2_2 PF13465.6 ORY97686.1 - 0.0004 20.7 1.6 0.0004 20.7 1.6 4.7 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY97686.1 - 0.00077 19.8 0.6 0.00077 19.8 0.6 5.1 5 0 0 5 5 4 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY97686.1 - 0.0012 19.5 14.9 0.067 13.8 0.3 4.8 2 1 3 5 5 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY97686.1 - 0.0059 17.3 0.5 0.0059 17.3 0.5 5.5 5 0 0 5 5 4 1 C2H2-type zinc finger Zap1_zf2 PF18217.1 ORY97686.1 - 0.03 14.3 0.8 0.11 12.5 0.8 2.1 1 0 0 1 1 1 0 Zap1 zinc finger 2 Glyco_transf_21 PF13506.6 ORY97686.1 - 0.036 13.5 0.0 0.48 9.9 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 21 Wzy_C PF04932.15 ORY97686.1 - 0.068 12.8 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 O-Antigen ligase DUF4542 PF15075.6 ORY97686.1 - 0.074 13.4 1.9 0.16 12.4 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) zf-C2H2_8 PF15909.5 ORY97686.1 - 0.21 11.9 7.2 0.67 10.3 7.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY97686.1 - 0.64 10.1 5.4 3.8 7.6 0.3 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger ABC_membrane PF00664.23 ORY97686.1 - 5 6.7 7.7 3 7.4 0.1 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region RRM_1 PF00076.22 ORY97687.1 - 4e-05 23.4 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY97687.1 - 0.00053 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY97687.1 - 0.09 12.8 0.3 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif PepSY_2 PF13670.6 ORY97687.1 - 0.28 11.2 0.2 0.28 11.2 0.2 2.0 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain FAM176 PF14851.6 ORY97688.1 - 0.086 12.5 0.3 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 FAM176 family SKA1 PF07160.12 ORY97688.1 - 0.38 10.6 3.7 0.64 9.8 3.7 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ATP-synt PF00231.19 ORY97689.1 - 1.2e-73 248.2 7.7 1.4e-73 248.1 7.7 1.0 1 0 0 1 1 1 1 ATP synthase PET117 PF15786.5 ORY97691.1 - 1.3e-21 76.7 1.4 1.5e-21 76.5 1.4 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Rho_Binding PF08912.11 ORY97691.1 - 0.00023 21.9 5.3 0.00032 21.5 5.3 1.2 1 0 0 1 1 1 1 Rho Binding EF-hand_14 PF17959.1 ORY97691.1 - 0.002 18.5 0.3 0.0025 18.1 0.3 1.1 1 0 0 1 1 1 1 EF-hand domain DUF2730 PF10805.8 ORY97691.1 - 0.018 15.2 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Cytadhesin_P30 PF07271.11 ORY97691.1 - 0.061 12.9 0.2 0.069 12.7 0.2 1.0 1 0 0 1 1 1 0 Cytadhesin P30/P32 Oleosin PF01277.17 ORY97691.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Oleosin Ribosomal_S27 PF01599.19 ORY97692.1 - 1.7e-27 95.3 2.0 1.7e-27 95.3 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 ORY97692.1 - 1.3e-13 50.4 0.0 2.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY97692.1 - 0.00039 20.2 0.0 0.00084 19.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Actin PF00022.19 ORY97693.1 - 1.3e-89 300.6 0.0 3.4e-88 296.0 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY97693.1 - 0.00014 20.8 0.0 0.3 9.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORY97693.1 - 0.0019 18.6 0.0 0.02 15.3 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Robl_LC7 PF03259.17 ORY97693.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain F_actin_cap_B PF01115.17 ORY97694.1 - 2.7e-105 351.3 0.0 3.2e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 ORY97694.1 - 6.3e-05 22.5 0.1 0.0016 17.9 0.1 2.6 1 1 1 2 2 2 1 F-actin capping protein alpha subunit Ribosomal_S21e PF01249.18 ORY97695.1 - 2.9e-39 133.0 0.0 3.2e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SRP9-21 PF05486.12 ORY97696.1 - 6.1e-10 39.4 3.8 2.1e-09 37.6 0.4 2.4 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Arrestin_N PF00339.29 ORY97697.1 - 8.8e-16 58.3 0.2 6.8e-11 42.4 0.0 3.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY97697.1 - 1.7e-15 57.6 14.9 5.3e-13 49.6 0.5 3.8 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 ORY97697.1 - 0.0027 16.8 0.4 1.5 7.7 0.0 2.4 2 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 26 Nnf1 PF03980.14 ORY97698.1 - 5e-14 52.6 8.2 1.1e-13 51.5 8.2 1.5 1 0 0 1 1 1 1 Nnf1 DUF948 PF06103.11 ORY97698.1 - 0.0069 16.6 0.3 4.7 7.6 0.1 2.4 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 ORY97698.1 - 0.03 14.4 4.1 0.037 14.1 4.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 ORY97698.1 - 0.082 10.9 2.0 0.1 10.5 2.0 1.2 1 0 0 1 1 1 0 Prominin CRA PF06589.11 ORY97698.1 - 0.67 10.1 4.8 1.1 9.4 4.7 1.5 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) JIP_LZII PF16471.5 ORY97698.1 - 2.4 8.4 12.5 1.8 8.8 1.8 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Vps16_C PF04840.12 ORY97699.1 - 1.4e-82 277.3 7.8 7e-82 275.0 3.7 2.2 1 1 1 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 ORY97699.1 - 4.3e-68 230.0 0.0 6.6e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 ORY97699.1 - 0.1 12.9 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 ORY97700.1 - 4e-35 121.3 0.3 7.5e-35 120.4 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY97700.1 - 2.9e-10 40.2 0.0 4.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ORY97700.1 - 0.015 14.8 0.1 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Nicastrin HMG_box PF00505.19 ORY97701.1 - 3.5e-40 136.3 0.7 2.1e-21 76.1 0.4 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY97701.1 - 4.5e-28 97.6 0.1 7.5e-13 48.9 0.1 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 ORY97701.1 - 0.00012 22.0 0.3 0.00031 20.7 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 ORY97701.1 - 0.00068 19.5 0.0 0.073 13.0 0.0 2.3 2 0 0 2 2 2 1 CHDNT (NUC034) domain Protamine_like PF06382.11 ORY97701.1 - 0.064 13.4 2.4 0.064 13.4 0.3 2.1 2 1 0 2 2 2 0 Protamine and protamine like BRO1 PF03097.18 ORY97702.1 - 4.8e-107 358.1 0.0 1.2e-106 356.8 0.0 1.7 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY97702.1 - 3.6e-68 230.0 6.1 5.7e-68 229.4 6.1 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Med21 PF11221.8 ORY97702.1 - 0.00099 19.4 0.8 0.00099 19.4 0.8 2.0 2 0 0 2 2 2 1 Subunit 21 of Mediator complex Occludin_ELL PF07303.13 ORY97702.1 - 0.019 15.7 1.3 0.097 13.4 0.8 2.5 1 1 0 1 1 1 0 Occludin homology domain DUF148 PF02520.17 ORY97702.1 - 0.039 14.1 1.4 0.15 12.2 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 Med9 PF07544.13 ORY97702.1 - 0.062 13.4 1.2 0.31 11.1 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Rsa3 PF14615.6 ORY97702.1 - 0.17 11.5 0.2 2.3 7.9 0.0 2.9 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Pkinase PF00069.25 ORY97703.1 - 4.8e-71 239.2 0.0 5.8e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97703.1 - 3e-35 121.8 0.0 3.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97703.1 - 8.3e-08 31.9 0.0 4.2e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY97703.1 - 6.5e-05 22.0 0.0 8.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY97703.1 - 0.02 13.7 0.1 0.032 13.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORY97703.1 - 0.13 12.2 0.5 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family RhoGEF PF00621.20 ORY97705.1 - 8.8e-06 26.1 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 ORY97705.1 - 0.046 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 PH domain CwfJ_C_1 PF04677.15 ORY97706.1 - 5.9e-34 116.6 0.1 9e-34 116.0 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ORY97706.1 - 1.2e-31 109.5 0.9 1.2e-31 109.5 0.9 2.6 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Sporozoite_P67 PF05642.11 ORY97706.1 - 2 6.4 5.4 7.8 4.4 1.0 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Glyco_hydro_28 PF00295.17 ORY97707.1 - 2.6e-67 227.2 22.5 3.6e-67 226.7 22.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1647 PF07801.11 ORY97708.1 - 0.00045 20.0 0.1 0.0018 18.1 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1647) BAR PF03114.18 ORY97710.1 - 2.6e-25 89.5 2.6 3.6e-25 89.0 2.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY97710.1 - 2.7e-12 46.1 0.1 6.2e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY97710.1 - 1.6e-10 40.6 0.1 3.4e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY97710.1 - 3e-08 33.2 0.0 6.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.25 ORY97711.1 - 5.8e-14 52.1 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 ORY97711.1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Mito_fiss_reg PF05308.11 ORY97711.1 - 0.066 13.3 6.7 0.53 10.3 3.9 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator DGF-1_C PF11040.8 ORY97711.1 - 0.13 12.2 6.0 3.1 7.8 0.1 2.8 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF1179 PF06678.11 ORY97711.1 - 2.3 8.2 5.5 7.9 6.5 5.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) 2-Hacid_dh_C PF02826.19 ORY97712.1 - 4.8e-52 175.9 0.0 7.4e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY97712.1 - 1.8e-15 56.8 0.0 2.4e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY97712.1 - 5.2e-05 23.5 0.0 8.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY97712.1 - 0.0029 18.1 0.0 0.0077 16.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ORY97712.1 - 0.0076 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CAP_GLY PF01302.25 ORY97713.1 - 2.2e-11 43.6 0.6 3.7e-11 42.9 0.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain Phage_int_SAM_6 PF18644.1 ORY97713.1 - 0.0043 17.1 0.5 0.54 10.3 0.0 2.9 1 1 1 3 3 3 1 Phage integrase SAM-like domain Rootletin PF15035.6 ORY97713.1 - 0.18 11.8 40.7 0.19 11.7 14.8 3.1 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion CRR7 PF12095.8 ORY97713.1 - 0.19 12.2 14.7 0.081 13.4 2.2 3.4 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 HAP1_N PF04849.13 ORY97713.1 - 0.26 10.4 39.5 0.6 9.3 16.0 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 ORY97713.1 - 6.2 6.1 27.5 0.17 11.2 12.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cofilin_ADF PF00241.20 ORY97714.1 - 9.9e-12 44.7 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 ORY97714.1 - 6.2e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Borrelia_P83 PF05262.11 ORY97714.1 - 0.00029 19.5 19.0 0.00041 19.0 19.0 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein PH_11 PF15413.6 ORY97714.1 - 0.0097 16.3 2.0 0.042 14.3 0.0 2.8 1 1 1 2 2 2 1 Pleckstrin homology domain CDC27 PF09507.10 ORY97714.1 - 1.7 7.9 41.4 2.2 7.6 41.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.11 ORY97714.1 - 8.4 6.4 31.7 13 5.8 31.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Methyltransf_16 PF10294.9 ORY97715.1 - 5e-29 101.2 0.1 7e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY97715.1 - 0.00021 21.2 0.0 0.00041 20.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY97715.1 - 0.00046 19.7 0.1 0.00058 19.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY97715.1 - 0.00094 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY97715.1 - 0.0036 18.0 0.0 0.0072 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY97715.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lipase_GDSL PF00657.22 ORY97716.1 - 3.8e-13 49.9 0.0 5.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY97716.1 - 1.2e-08 35.6 1.1 1.5e-07 32.0 1.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PLA2_B PF01735.18 ORY97717.1 - 8.3e-37 126.7 0.2 1e-17 63.8 0.0 2.6 3 0 0 3 3 3 2 Lysophospholipase catalytic domain OSTbeta PF15048.6 ORY97717.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein RACo_linker PF17650.1 ORY97718.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RACo linker region MRP-L20 PF12824.7 ORY97720.1 - 5.8e-26 91.6 1.8 8.4e-26 91.1 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 ORY97720.1 - 0.00053 20.1 0.2 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 Neugrin HTH_32 PF13565.6 ORY97720.1 - 0.03 14.9 0.1 0.064 13.9 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 ORY97720.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain Ku_PK_bind PF08785.11 ORY97721.1 - 2.1e-35 121.5 0.1 5.8e-35 120.0 0.1 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 ORY97721.1 - 1e-32 113.5 0.0 2.1e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ORY97721.1 - 9.9e-11 41.8 0.0 8.9e-10 38.7 0.0 2.4 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain CPBP PF02517.16 ORY97723.1 - 1e-17 64.3 6.2 1e-17 64.3 6.2 2.8 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease DUF543 PF04418.12 ORY97723.1 - 0.019 14.9 2.1 0.042 13.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) HAD PF12710.7 ORY97724.1 - 2.5e-17 63.9 0.0 4.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY97724.1 - 1.8e-15 57.8 0.8 3.1e-15 57.0 0.8 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY97724.1 - 2.7e-10 40.4 0.0 2.5e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SPX PF03105.19 ORY97724.1 - 5.7e-09 36.4 0.8 0.00027 21.0 0.1 2.4 1 1 1 2 2 2 2 SPX domain ACT_6 PF13740.6 ORY97724.1 - 1e-07 31.8 0.0 2.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain Put_Phosphatase PF06888.12 ORY97724.1 - 1.9e-05 24.2 0.1 0.016 14.6 0.0 2.5 3 0 0 3 3 3 2 Putative Phosphatase HAD_2 PF13419.6 ORY97724.1 - 0.001 19.2 0.3 2.5 8.2 0.0 3.2 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 ORY97724.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF4407 PF14362.6 ORY97725.1 - 0.93 8.8 10.1 1.2 8.4 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 ORY97725.1 - 1.7 7.7 3.9 2 7.5 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cytadhesin_P30 PF07271.11 ORY97725.1 - 2.5 7.6 4.9 4 6.9 4.9 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 XRN_M PF17846.1 ORY97725.1 - 2.9 6.7 11.9 3.8 6.4 11.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF349 PF03993.12 ORY97725.1 - 4.8 7.6 21.6 2 8.8 17.5 2.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) DUF4192 PF13830.6 ORY97725.1 - 4.8 7.1 6.3 5.9 6.9 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) Apis_Csd PF11671.8 ORY97725.1 - 4.9 7.1 9.4 4.5 7.3 7.2 1.9 1 1 1 2 2 2 0 Complementary sex determiner protein DUF1943 PF09172.11 ORY97725.1 - 5 6.3 7.8 7.7 5.7 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Ndc1_Nup PF09531.10 ORY97725.1 - 6.8 5.2 6.8 7.5 5.1 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0767 PF15990.5 ORY97726.1 - 0.016 15.3 0.9 0.026 14.6 0.9 1.5 1 1 0 1 1 1 0 UPF0767 family DUF3180 PF11377.8 ORY97726.1 - 0.02 15.0 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) V_ATPase_I PF01496.19 ORY97726.1 - 0.093 10.6 0.0 0.11 10.4 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAR1 PF03101.15 ORY97727.1 - 2.4e-06 28.1 3.1 5.6e-06 27.0 3.1 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain PSK_trans_fac PF07704.11 ORY97727.1 - 0.05 14.4 0.6 0.44 11.3 0.5 2.6 1 1 0 1 1 1 0 Rv0623-like transcription factor HTH_32 PF13565.6 ORY97727.1 - 0.052 14.2 2.4 0.19 12.4 0.2 2.8 1 1 1 2 2 2 0 Homeodomain-like domain F-box-like PF12937.7 ORY97728.1 - 3.2e-07 30.1 0.2 8.9e-07 28.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like Nop14 PF04147.12 ORY97728.1 - 0.011 13.9 13.1 0.015 13.6 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family F-box_4 PF15966.5 ORY97728.1 - 0.024 14.5 0.3 0.058 13.3 0.3 1.6 1 0 0 1 1 1 0 F-box F-box PF00646.33 ORY97728.1 - 0.048 13.5 0.4 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 F-box domain Lin-8 PF03353.15 ORY97728.1 - 0.082 12.5 12.6 0.13 11.8 12.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 ORY97728.1 - 0.16 11.4 12.5 0.23 10.8 12.5 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 ORY97728.1 - 1.4 7.1 17.2 2.1 6.5 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1387 PF07139.11 ORY97728.1 - 2.4 7.8 7.2 3.7 7.2 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Nop53 PF07767.11 ORY97728.1 - 2.5 7.4 17.4 3.8 6.8 17.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FYDLN_acid PF09538.10 ORY97728.1 - 3.5 8.3 15.8 5.8 7.6 12.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PPP4R2 PF09184.11 ORY97728.1 - 5 6.6 16.4 10 5.6 10.1 2.6 3 0 0 3 3 3 0 PPP4R2 Menin PF05053.13 ORY97728.1 - 5.2 5.3 7.3 7.3 4.8 7.3 1.1 1 0 0 1 1 1 0 Menin Nop25 PF09805.9 ORY97728.1 - 7.6 7.0 18.7 13 6.3 12.2 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PPR_2 PF13041.6 ORY97729.1 - 4.4e-56 186.9 3.1 1.9e-12 47.2 0.2 9.7 7 2 3 10 10 10 7 PPR repeat family PPR_3 PF13812.6 ORY97729.1 - 1.6e-44 149.8 0.7 2.6e-10 40.2 0.0 9.3 4 2 7 11 11 11 8 Pentatricopeptide repeat domain PPR PF01535.20 ORY97729.1 - 1.1e-31 106.9 0.4 7.4e-05 22.7 0.0 9.8 10 0 0 10 10 10 6 PPR repeat PPR_1 PF12854.7 ORY97729.1 - 6.9e-23 80.1 0.2 0.00029 20.5 0.0 7.6 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 ORY97729.1 - 3.2e-16 59.3 0.1 1.1e-06 28.2 0.0 4.2 2 1 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORY97729.1 - 0.00071 20.0 1.1 0.52 10.7 0.3 3.7 3 1 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORY97729.1 - 0.025 13.5 0.9 4.9 5.9 0.0 3.0 1 1 2 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 ORY97729.1 - 0.082 13.4 1.2 2.2 8.8 0.3 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Imm3 PF14425.6 ORY97729.1 - 0.09 12.8 1.8 0.54 10.3 0.1 2.8 2 1 2 4 4 4 0 Immunity protein Imm3 KDZ PF18758.1 ORY97730.1 - 2.9e-17 63.0 0.0 7.4e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 ORY97730.1 - 0.0002 21.5 0.1 0.0005 20.2 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 ORY97730.1 - 0.0048 17.0 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases PGBA_C PF15437.6 ORY97730.1 - 0.062 13.7 0.1 22 5.5 0.2 2.6 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal IQ_SEC7_PH PF16453.5 ORY97731.1 - 0.13 12.3 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 PH domain Cpn60_TCP1 PF00118.24 ORY97733.1 - 2.2e-168 560.9 2.8 2.8e-168 560.6 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pept_tRNA_hydro PF01195.19 ORY97734.1 - 3.4e-44 150.8 0.0 4.2e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase cobW PF02492.19 ORY97735.1 - 1.1e-53 181.4 0.7 1.4e-53 181.1 0.7 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORY97735.1 - 9.2e-22 76.8 0.0 1.7e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ORY97735.1 - 0.00024 21.0 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MobB PF03205.14 ORY97735.1 - 0.00067 19.6 0.1 0.002 18.0 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 ORY97735.1 - 0.0047 17.0 0.3 0.027 14.6 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 ORY97735.1 - 0.007 15.5 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 ORY97735.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY97735.1 - 0.017 15.4 0.1 0.046 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY97735.1 - 0.02 15.5 0.5 0.098 13.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 ORY97735.1 - 0.031 13.8 3.2 0.088 12.3 3.2 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 ORY97735.1 - 0.04 14.0 0.3 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY97735.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ORY97735.1 - 0.072 13.6 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 ORY97735.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 ORY97735.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORY97735.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 ORY97735.1 - 0.12 12.0 1.3 0.29 10.8 1.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 ORY97735.1 - 0.15 12.3 0.3 0.39 11.0 0.1 2.0 2 1 0 2 2 1 0 AAA domain FAD_binding_4 PF01565.23 ORY97736.1 - 1.5e-28 99.3 3.9 2.8e-28 98.4 3.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY97736.1 - 1.6e-05 24.9 0.0 4.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Adenyl_transf PF04439.12 ORY97736.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Glyco_hydro_3 PF00933.21 ORY97737.1 - 2.3e-63 214.5 0.0 4.1e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ORY97737.1 - 1.2e-52 178.8 0.0 2.2e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ORY97737.1 - 1.4e-20 73.1 0.6 1.4e-20 73.1 0.6 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain HypD PF01924.16 ORY97737.1 - 0.033 13.3 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Spt5-NGN PF03439.13 ORY97737.1 - 0.11 12.5 0.1 16 5.5 0.2 2.6 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section Sugar_tr PF00083.24 ORY97738.1 - 2.7e-112 375.9 24.9 3.3e-112 375.6 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY97738.1 - 4.9e-24 84.9 22.1 4.9e-24 84.9 22.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ORY97738.1 - 0.002 16.5 8.8 0.003 15.9 0.6 3.0 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_31 PF01055.26 ORY97739.1 - 2.5e-119 399.4 0.8 3.2e-119 399.0 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY97739.1 - 2.1e-06 28.0 0.3 1.3e-05 25.4 0.3 2.4 1 1 0 1 1 1 1 Galactose mutarotase-like DUF4968 PF16338.5 ORY97739.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Romo1 PF10247.9 ORY97740.1 - 4.5e-25 87.8 13.5 5.3e-25 87.6 13.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF563 PF04577.14 ORY97742.1 - 2.7e-07 30.9 0.0 7.1e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) CHMI PF02962.15 ORY97742.1 - 0.05 13.9 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 5-carboxymethyl-2-hydroxymuconate isomerase Septin PF00735.18 ORY97743.1 - 7e-114 379.9 0.9 9.8e-114 379.4 0.9 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY97743.1 - 5.9e-08 32.8 0.0 1.9e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY97743.1 - 3.1e-07 30.1 4.0 3.5e-06 26.7 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY97743.1 - 7.2e-07 29.3 0.8 1.7e-05 24.8 0.3 2.8 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORY97743.1 - 8.3e-05 22.8 0.1 0.00021 21.5 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORY97743.1 - 0.00078 19.7 1.2 0.0052 17.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain Ras PF00071.22 ORY97743.1 - 0.0011 18.6 0.3 0.003 17.2 0.3 1.7 1 1 0 1 1 1 1 Ras family Pox_A32 PF04665.12 ORY97743.1 - 0.0012 18.4 0.4 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_16 PF13191.6 ORY97743.1 - 0.0022 18.4 0.5 0.0088 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 ORY97743.1 - 0.0027 17.4 0.1 0.0054 16.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Gtr1_RagA PF04670.12 ORY97743.1 - 0.0045 16.4 0.2 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 ORY97743.1 - 0.0048 17.3 0.1 0.032 14.6 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AIG1 PF04548.16 ORY97743.1 - 0.0054 16.1 0.0 0.018 14.4 0.0 1.9 1 0 0 1 1 1 1 AIG1 family AAA_7 PF12775.7 ORY97743.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORY97743.1 - 0.021 14.2 0.1 0.054 12.8 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 ORY97743.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PRK PF00485.18 ORY97743.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 ORY97743.1 - 0.029 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 ORY97743.1 - 0.03 14.0 0.2 0.03 14.0 0.2 1.9 2 1 0 2 2 2 0 AAA domain FOXP-CC PF16159.5 ORY97743.1 - 0.039 14.6 1.2 0.039 14.6 1.2 2.8 3 1 1 4 4 2 0 FOXP coiled-coil domain AAA_25 PF13481.6 ORY97743.1 - 0.043 13.4 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY97743.1 - 0.053 14.0 0.7 0.15 12.6 0.0 2.1 2 1 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 ORY97743.1 - 0.059 12.6 0.0 0.16 11.2 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.9 ORY97743.1 - 0.06 13.1 0.6 1 9.1 0.1 2.7 2 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 ORY97743.1 - 0.077 13.2 2.4 0.13 12.5 0.0 2.6 3 1 1 4 4 2 0 AAA domain AAA PF00004.29 ORY97743.1 - 0.093 13.2 0.3 0.78 10.2 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY97743.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 ORY97743.1 - 0.15 11.9 0.9 1.3 8.7 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DivIC PF04977.15 ORY97743.1 - 0.9 9.3 5.2 3.1 7.6 5.2 1.9 1 0 0 1 1 1 0 Septum formation initiator Dynamin_N PF00350.23 ORY97743.1 - 1.9 8.5 7.9 6 6.9 0.1 3.3 2 1 1 3 3 3 0 Dynamin family APG6_N PF17675.1 ORY97743.1 - 3.1 8.3 16.0 0.29 11.6 10.6 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Oxidored_FMN PF00724.20 ORY97744.1 - 1.9e-101 339.7 0.0 2.2e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MMR_HSR1 PF01926.23 ORY97745.1 - 1.8e-18 66.6 0.3 2e-14 53.6 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY97745.1 - 1.8e-10 40.5 0.2 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORY97745.1 - 2.3e-07 30.6 0.1 2.7e-05 23.8 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY97745.1 - 1e-06 28.8 1.2 0.0049 16.8 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORY97745.1 - 0.00014 22.0 1.7 0.0069 16.5 0.4 3.0 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 ORY97745.1 - 0.01 15.2 0.4 0.24 10.7 0.1 2.1 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 ORY97745.1 - 0.014 15.0 0.1 0.14 11.8 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1_Xtn PF16897.5 ORY97745.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 ORY97745.1 - 0.073 13.6 0.1 0.34 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY97745.1 - 0.082 11.9 0.1 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 ORY97745.1 - 0.09 13.0 0.7 6.1 7.1 0.0 3.1 2 1 2 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY97745.1 - 0.12 12.7 0.0 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_L38e PF01781.18 ORY97746.1 - 6.4e-35 119.1 5.5 6.9e-35 119.0 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Pkinase PF00069.25 ORY97747.1 - 1.1e-60 205.2 0.0 1.7e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97747.1 - 1.9e-43 148.6 0.0 2.6e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97747.1 - 3.9e-06 26.4 0.0 6.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY97747.1 - 1.2e-05 25.4 0.2 2e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY97747.1 - 0.0013 17.7 0.1 0.0024 16.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 ORY97747.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 ORY97747.1 - 0.048 13.3 0.1 0.16 11.6 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 ORY97747.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Gemin6 PF06372.12 ORY97748.1 - 6.5e-12 45.3 0.0 8.2e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Gemin6 protein AD PF09793.9 ORY97748.1 - 0.04 14.0 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Whi5 PF08528.11 ORY97749.1 - 0.062 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Whi5 like Arm PF00514.23 ORY97750.1 - 9.1e-82 266.9 14.5 8.5e-12 44.7 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 ORY97750.1 - 4.5e-23 81.5 2.7 8.3e-23 80.6 2.7 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 ORY97750.1 - 2.4e-21 75.0 0.2 9.6e-21 73.1 0.1 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 ORY97750.1 - 1.3e-20 73.5 0.2 6.3e-08 33.0 0.0 6.2 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 ORY97750.1 - 7.5e-16 58.3 0.0 4e-06 27.1 0.0 5.4 2 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 ORY97750.1 - 2.6e-15 55.2 0.1 0.00017 21.5 0.0 6.8 6 0 0 6 6 6 2 HEAT repeat Arm_2 PF04826.13 ORY97750.1 - 0.00012 21.6 0.0 6.5 6.1 0.0 4.3 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 ORY97750.1 - 0.00012 20.8 0.1 0.024 13.2 0.1 2.4 1 1 1 2 2 2 2 Adaptin N terminal region RICTOR_V PF14668.6 ORY97750.1 - 0.00018 21.7 0.5 0.079 13.2 0.0 3.8 4 1 1 5 5 4 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 ORY97750.1 - 0.00031 20.8 0.0 0.47 10.6 0.0 3.4 3 2 0 3 3 3 2 V-ATPase subunit H HEAT_PBS PF03130.16 ORY97750.1 - 0.00053 20.4 0.7 0.15 12.8 0.1 4.1 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat DUF3552 PF12072.8 ORY97750.1 - 0.038 13.4 2.2 0.069 12.6 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CDC27 PF09507.10 ORY97750.1 - 0.61 9.4 3.1 0.94 8.8 3.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sds3 PF08598.11 ORY97751.1 - 2.1e-13 50.8 10.5 2.1e-13 50.8 10.5 2.5 1 1 1 2 2 2 1 Sds3-like Stork_head PF10264.9 ORY97751.1 - 0.094 12.9 0.4 0.23 11.7 0.1 1.7 1 1 0 1 1 1 0 Winged helix Storkhead-box1 domain Tox-ODYAM1 PF15642.6 ORY97751.1 - 0.19 10.7 7.6 0.26 10.2 7.6 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus IMUP PF15761.5 ORY97751.1 - 0.59 10.9 12.6 0.35 11.6 10.2 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein CH PF00307.31 ORY97752.1 - 2.9e-30 104.6 0.6 5e-14 52.4 0.0 4.1 4 0 0 4 4 4 2 Calponin homology (CH) domain GAS2 PF02187.17 ORY97752.1 - 5.4e-12 45.6 0.1 1.8e-11 44.0 0.1 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.8 ORY97752.1 - 0.0002 21.1 0.4 0.0025 17.6 0.0 3.0 3 0 0 3 3 3 1 CAMSAP CH domain Mating_N PF12731.7 ORY97752.1 - 0.48 10.5 6.7 2.7 8.1 0.0 6.0 5 0 0 5 5 5 0 Mating-type protein beta 1 DASH_Dam1 PF08653.10 ORY97752.1 - 2.6 7.9 5.4 77 3.2 0.1 6.4 6 0 0 6 6 6 0 DASH complex subunit Dam1 ApoO PF09769.9 ORY97752.1 - 2.9 7.9 14.1 5.5 7.0 0.0 6.5 7 0 0 7 7 7 0 Apolipoprotein O Ldh_1_C PF02866.18 ORY97753.1 - 9.6e-49 165.5 0.2 1.8e-48 164.6 0.2 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORY97753.1 - 3.9e-48 163.1 0.1 5.8e-48 162.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ORY97753.1 - 1.6e-05 24.0 0.0 6.9e-05 22.0 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 ORY97753.1 - 0.00054 20.1 0.3 0.0017 18.4 0.1 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 ORY97753.1 - 0.0044 16.9 0.3 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 ORY97753.1 - 0.0049 16.2 1.1 0.13 11.6 0.1 3.0 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 ORY97753.1 - 0.0093 15.5 1.6 5.7 6.4 0.2 3.2 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase ADH_N PF08240.12 ORY97754.1 - 1.2e-31 108.8 1.0 1.2e-31 108.8 1.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY97754.1 - 1.4e-20 73.6 0.2 2.4e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY97754.1 - 4.4e-08 34.3 0.0 9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY97754.1 - 1.3e-05 24.8 0.7 0.012 15.1 0.1 2.8 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORY97754.1 - 0.0067 15.7 0.4 0.02 14.2 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 ORY97754.1 - 0.026 13.7 0.4 0.092 12.0 0.1 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY97754.1 - 0.098 12.9 0.2 0.24 11.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_S8 PF00082.22 ORY97755.1 - 8.5e-43 146.7 5.0 1.4e-42 146.0 5.0 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY97755.1 - 1.4e-16 61.2 2.3 3e-16 60.2 2.3 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORY97755.1 - 9.8e-15 54.4 0.4 3.3e-14 52.7 0.4 1.9 1 0 0 1 1 1 1 PA domain DUF11 PF01345.18 ORY97755.1 - 0.0078 16.5 1.6 0.24 11.7 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF11 fn3_6 PF17766.1 ORY97755.1 - 0.045 13.9 0.2 0.14 12.3 0.2 1.9 1 0 0 1 1 1 0 Fibronectin type-III domain DNA_ligase_C PF17879.1 ORY97755.1 - 0.055 13.5 0.1 0.76 9.8 0.1 2.6 2 0 0 2 2 2 0 DNA ligase C-terminal domain Motile_Sperm PF00635.26 ORY97755.1 - 0.12 12.3 1.9 12 5.8 0.0 3.0 2 1 1 3 3 3 0 MSP (Major sperm protein) domain Inhibitor_I9 PF05922.16 ORY97755.1 - 0.18 12.5 0.4 1.6 9.5 0.1 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I9 HSF_DNA-bind PF00447.17 ORY97756.1 - 4.1e-32 110.7 2.9 4.1e-32 110.7 2.9 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding HAUS6_N PF14661.6 ORY97756.1 - 0.0027 17.3 1.2 0.0044 16.6 1.2 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.13 ORY97756.1 - 0.59 9.3 4.5 0.18 11.0 1.1 1.7 2 0 0 2 2 2 0 TMPIT-like protein SKA1 PF07160.12 ORY97756.1 - 1.3 8.8 7.6 0.1 12.4 1.9 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ADH_zinc_N PF00107.26 ORY97757.1 - 1.6e-35 121.9 0.0 2.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY97757.1 - 1e-14 55.7 0.0 2.6e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY97757.1 - 5.5e-07 29.4 0.0 1.4e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ORY97757.1 - 0.002 17.4 0.3 0.0033 16.7 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ORY97757.1 - 0.014 15.6 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N_2 PF16884.5 ORY97757.1 - 0.08 12.8 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Tax PF02959.16 ORY97757.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 HTLV Tax GFO_IDH_MocA PF01408.22 ORY97758.1 - 2.2e-25 89.8 0.0 3.1e-24 86.1 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY97758.1 - 3.7e-15 55.9 0.0 8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 ORY97758.1 - 0.0011 19.6 0.1 0.0021 18.7 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ORY97758.1 - 0.0036 17.7 0.0 0.0075 16.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 ORY97758.1 - 0.1 13.3 0.1 0.25 12.0 0.1 1.7 1 1 0 1 1 1 0 CoA binding domain Pterin_bind PF00809.22 ORY97759.1 - 3.3e-85 285.7 0.3 6.1e-85 284.8 0.1 1.6 2 0 0 2 2 2 1 Pterin binding enzyme FolB PF02152.18 ORY97759.1 - 4.9e-49 165.5 1.5 6.2e-24 84.7 0.2 2.7 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 ORY97759.1 - 4.8e-37 126.9 0.0 2e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Thioredoxin PF00085.20 ORY97760.1 - 0.014 15.3 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin DHHC PF01529.20 ORY97762.1 - 3.5e-39 134.0 5.9 3.5e-39 134.0 5.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase FAM72 PF14976.6 ORY97763.1 - 1.4e-51 174.4 2.0 1.9e-51 174.0 2.0 1.1 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 ORY97763.1 - 0.0067 16.6 5.0 0.013 15.7 5.0 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 ORY97763.1 - 0.061 12.2 2.5 0.17 10.7 0.1 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIG-I_C-RD PF11648.8 ORY97763.1 - 0.87 9.8 5.1 3 8.1 5.1 1.9 1 1 0 1 1 1 0 C-terminal domain of RIG-I Pkinase PF00069.25 ORY97764.1 - 4.6e-47 160.6 0.0 5.2e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97764.1 - 1.2e-23 83.7 0.0 1.6e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY97764.1 - 0.00031 20.1 0.1 0.018 14.4 0.0 2.3 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 ORY97764.1 - 0.0084 15.8 0.1 0.019 14.6 0.0 1.6 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Rep_fac-A_3 PF08661.11 ORY97765.1 - 3.7e-22 78.7 0.0 4.1e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Myosin_TH1 PF06017.13 ORY97765.1 - 0.017 14.8 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding WGG PF10273.9 ORY97766.1 - 3.9e-30 104.3 0.2 1.2e-29 102.7 0.1 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 GCIP PF13324.6 ORY97766.1 - 0.097 12.3 1.6 0.15 11.7 1.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 ORY97766.1 - 1.4 8.2 5.0 1.6 8.0 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein zf-PARP PF00645.18 ORY97767.1 - 2.3e-06 28.4 1.5 2.3e-06 28.4 1.5 3.1 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Mitofilin PF09731.9 ORY97767.1 - 1.6 7.4 33.3 2.4 6.9 33.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LAP1C PF05609.12 ORY97767.1 - 1.7 7.7 25.5 2.3 7.2 25.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Homeodomain PF00046.29 ORY97768.1 - 0.0028 17.4 0.1 0.0075 16.1 0.1 1.8 1 0 0 1 1 1 1 Homeodomain SR-25 PF10500.9 ORY97768.1 - 0.046 13.3 14.5 0.075 12.6 14.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Homeobox_KN PF05920.11 ORY97768.1 - 0.13 12.2 2.6 0.15 12.0 0.3 2.3 2 0 0 2 2 2 0 Homeobox KN domain Smg8_Smg9 PF10220.9 ORY97768.1 - 0.14 10.4 5.8 0.18 10.1 5.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF775 PF05603.12 ORY97768.1 - 0.23 11.0 2.1 0.38 10.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) RR_TM4-6 PF06459.12 ORY97768.1 - 0.25 11.1 9.0 0.35 10.7 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 ORY97768.1 - 0.42 10.5 11.8 0.5 10.3 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 ORY97768.1 - 1.6 8.4 4.2 2.5 7.8 4.2 1.3 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 ORY97768.1 - 1.6 8.7 4.5 2.1 8.3 4.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 ORY97768.1 - 7.1 5.3 7.9 8.8 5.0 7.9 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 ORY97768.1 - 7.7 5.1 10.6 8.9 4.9 10.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CotH PF08757.11 ORY97769.1 - 5.4e-35 121.5 0.0 7.5e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 CotH kinase protein Peptidase_M16 PF00675.20 ORY97770.1 - 8e-19 68.1 0.5 1.5e-18 67.2 0.5 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY97770.1 - 4.5e-15 56.1 0.0 9.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain OPT PF03169.15 ORY97771.1 - 2.8e-191 637.3 51.7 3.2e-191 637.2 51.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DEAD PF00270.29 ORY97772.1 - 6.1e-46 156.4 0.0 1.1e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY97772.1 - 1.9e-30 105.5 0.0 5.2e-30 104.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY97772.1 - 3.4e-05 23.9 0.0 6.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY97772.1 - 0.005 15.7 0.0 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Aa_trans PF01490.18 ORY97775.1 - 5.2e-60 203.3 31.9 6.2e-60 203.0 31.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY97775.1 - 4.3e-09 35.7 43.2 5.9e-09 35.2 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease Metallophos PF00149.28 ORY97776.1 - 4.5e-35 122.0 0.3 7.6e-35 121.3 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 ORY97776.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) HSA PF07529.13 ORY97777.1 - 2e-15 56.9 0.7 2e-15 56.9 0.7 4.2 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 ORY97777.1 - 4.7e-06 26.7 0.2 1.5e-05 25.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY97777.1 - 2e-05 24.7 2.5 3.2e-05 24.1 0.2 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Med15 PF09606.10 ORY97777.1 - 6.7e-05 21.8 92.1 0.00012 21.0 92.1 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Conotoxin PF02950.17 ORY97779.1 - 0.0012 19.9 1.7 0.0015 19.5 1.7 1.3 1 1 0 1 1 1 1 Conotoxin Fungal_trans PF04082.18 ORY97780.1 - 2.5e-44 151.3 0.0 4.1e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY97780.1 - 7.9e-10 38.7 11.3 7.9e-10 38.7 11.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_C PF02752.22 ORY97781.1 - 1.6e-11 44.8 0.2 1.7e-09 38.2 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain MID_MedPIWI PF18296.1 ORY97781.1 - 0.034 13.9 0.8 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 MID domain of medPIWI Arrestin_N PF00339.29 ORY97781.1 - 0.062 13.3 0.0 0.37 10.8 0.0 2.3 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain zf-RING_2 PF13639.6 ORY97783.1 - 6e-12 45.7 6.9 6e-12 45.7 6.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY97783.1 - 2.9e-08 33.4 6.9 2.9e-08 33.4 6.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY97783.1 - 1e-07 31.6 6.7 2e-07 30.6 6.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY97783.1 - 3.9e-07 30.2 7.6 3.9e-07 30.2 7.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 ORY97783.1 - 4e-07 30.2 4.5 4e-07 30.2 4.5 2.6 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4 PF00097.25 ORY97783.1 - 5.6e-07 29.3 6.7 5.6e-07 29.3 6.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY97783.1 - 5.8e-07 29.4 1.9 5.8e-07 29.4 1.9 2.3 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY97783.1 - 6.5e-06 25.9 4.9 1.7e-05 24.6 4.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY97783.1 - 1.2e-05 25.1 3.7 1.2e-05 25.1 3.7 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY97783.1 - 2.2e-05 24.3 4.6 2.2e-05 24.3 4.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY97783.1 - 0.00014 21.8 2.5 0.00062 19.8 2.4 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY97783.1 - 0.005 16.4 4.9 0.01 15.4 4.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF983 PF06170.12 ORY97783.1 - 0.011 16.2 3.2 1.1 9.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Rad50_zn_hook PF04423.14 ORY97783.1 - 0.023 14.5 2.3 0.034 14.0 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif HypA PF01155.19 ORY97783.1 - 0.059 13.4 8.7 0.82 9.7 1.5 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RINGv PF12906.7 ORY97783.1 - 0.28 11.3 4.2 0.78 9.9 4.2 1.9 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 ORY97783.1 - 9.9 6.4 13.0 2.5 8.4 5.6 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain Aph-1 PF06105.12 ORY97784.1 - 8.2e-51 172.6 20.4 9.6e-51 172.4 20.4 1.0 1 0 0 1 1 1 1 Aph-1 protein HMG_box PF00505.19 ORY97785.1 - 1.1e-23 83.4 2.3 1.5e-23 82.9 2.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY97785.1 - 3.1e-16 59.7 3.5 4.6e-16 59.2 3.5 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 ORY97785.1 - 0.051 13.5 2.9 0.077 13.0 2.9 1.6 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Mito_carr PF00153.27 ORY97786.1 - 4.8e-52 173.8 1.7 4.5e-20 71.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY97786.1 - 0.00097 18.4 0.7 0.014 14.6 0.0 2.5 3 0 0 3 3 3 1 Gammaproteobacterial serine protease Orthopox_C10L PF07020.11 ORY97786.1 - 0.12 13.1 0.4 1.7 9.4 0.1 2.5 3 0 0 3 3 3 0 Orthopoxvirus C10L protein Rbsn PF11464.8 ORY97787.1 - 2.2e-13 49.7 0.9 5.7e-13 48.4 0.9 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 ORY97787.1 - 1.3e-12 47.7 25.1 9.2e-11 41.7 4.0 3.9 4 0 0 4 4 4 3 FYVE zinc finger Raf1_HTH PF18579.1 ORY97787.1 - 0.11 12.2 0.2 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain zf-C2H2_4 PF13894.6 ORY97787.1 - 0.15 12.9 0.1 0.15 12.9 0.1 5.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY97787.1 - 0.21 12.1 0.1 0.21 12.1 0.1 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2887 PF11103.8 ORY97788.1 - 0.056 13.4 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) Transposase_31 PF04754.12 ORY97788.1 - 0.059 13.0 0.0 0.076 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative transposase, YhgA-like Nitrophorin PF02087.15 ORY97788.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Nitrophorin SPX PF03105.19 ORY97789.1 - 5.3e-29 102.3 8.9 2.6e-13 50.6 1.7 3.1 1 1 2 3 3 3 3 SPX domain zf-RING_UBOX PF13445.6 ORY97789.1 - 2.8e-07 30.5 2.3 2.8e-07 30.5 2.3 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY97789.1 - 6.5e-06 26.4 7.9 6.5e-06 26.4 7.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY97789.1 - 9e-06 25.4 6.2 9e-06 25.4 6.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY97789.1 - 9.9e-06 25.6 6.5 2.4e-05 24.4 6.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY97789.1 - 1.2e-05 25.0 6.8 2.8e-05 23.9 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY97789.1 - 2.2e-05 24.2 5.4 2.2e-05 24.2 5.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY97789.1 - 0.0001 22.2 8.1 0.00053 19.9 8.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY97789.1 - 0.0003 20.6 9.6 0.017 15.0 10.0 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Mei5_like PF17021.5 ORY97789.1 - 0.075 13.1 1.7 0.15 12.2 1.7 1.5 1 0 0 1 1 1 0 Putative double-strand recombination repair-like zf-rbx1 PF12678.7 ORY97789.1 - 1.6 9.0 8.2 7.1 7.0 8.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 ORY97789.1 - 6 6.7 9.5 0.38 10.6 4.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Gram_pos_anchor PF00746.21 ORY97790.1 - 0.074 13.0 0.5 0.16 12.0 0.3 1.7 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Aldo_ket_red PF00248.21 ORY97791.1 - 1.7e-45 155.5 0.0 2.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family R3H PF01424.22 ORY97792.1 - 5.3e-17 61.6 0.1 9.4e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 ORY97792.1 - 3.9e-10 39.6 82.6 1.5e-05 24.9 14.2 14.9 16 1 0 16 16 16 6 NF-X1 type zinc finger Ndc1_Nup PF09531.10 ORY97792.1 - 5.5 5.5 13.7 7.3 5.1 13.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 ORY97793.1 - 2.3e-36 123.4 0.2 1.9e-18 66.1 0.1 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY97793.1 - 5.8e-09 36.0 0.3 5e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORY97793.1 - 3.9e-06 26.5 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 ORY97793.1 - 0.022 14.4 0.0 7.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Zn_clus PF00172.18 ORY97794.1 - 0.0034 17.5 16.1 0.0058 16.7 16.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 ORY97795.1 - 1.8e-57 191.2 2.0 1.4e-19 69.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein P5CR_dimer PF14748.6 ORY97797.1 - 6.6e-28 97.0 1.0 1.6e-27 95.7 1.0 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORY97797.1 - 6.5e-18 65.1 0.3 4.8e-17 62.3 0.0 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 ORY97797.1 - 1.1e-07 32.0 0.4 9.9e-07 28.9 0.0 2.5 2 1 1 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 ORY97797.1 - 0.00026 21.2 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 ORY97797.1 - 0.0031 16.6 0.1 0.0076 15.3 0.0 1.6 2 0 0 2 2 2 1 Prephenate dehydrogenase ApbA PF02558.16 ORY97797.1 - 0.0041 16.8 0.0 0.053 13.2 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Phosducin PF02114.16 ORY97798.1 - 8.1e-24 84.0 0.1 1.4e-23 83.2 0.1 1.3 1 1 0 1 1 1 1 Phosducin Arf PF00025.21 ORY97799.1 - 5.3e-77 257.2 0.1 5.9e-77 257.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY97799.1 - 7.9e-16 58.4 0.1 1e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY97799.1 - 1.6e-13 50.5 0.0 1.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY97799.1 - 5.3e-12 45.6 2.6 8.1e-08 31.8 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY97799.1 - 7.6e-12 45.0 0.0 9.4e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY97799.1 - 3.1e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY97799.1 - 4.2e-05 23.6 0.0 6.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY97799.1 - 0.0035 16.7 0.1 0.0052 16.1 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase SpoOE-like PF09388.10 ORY97799.1 - 0.14 12.1 0.4 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein ECH_1 PF00378.20 ORY97800.1 - 3e-28 98.8 0.1 3.9e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY97800.1 - 2.2e-16 60.3 0.2 2.6e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 ORY97801.1 - 1.6e-46 158.8 0.0 9.6e-33 113.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97801.1 - 2.7e-29 102.2 0.0 1.5e-28 99.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY97801.1 - 1.5e-07 30.6 0.0 2.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Rad50_zn_hook PF04423.14 ORY97801.1 - 0.0066 16.3 0.2 0.017 14.9 0.1 1.7 2 0 0 2 2 2 1 Rad50 zinc hook motif Kinase-like PF14531.6 ORY97801.1 - 0.0075 15.6 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY97801.1 - 0.14 12.0 3.1 0.29 11.0 3.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3248 PF11609.8 ORY97802.1 - 0.19 11.6 0.1 29 4.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3248) Casein_kappa PF00997.18 ORY97802.1 - 0.59 10.2 12.5 1.1 9.3 12.5 1.4 1 0 0 1 1 1 0 Kappa casein Mucin PF01456.17 ORY97802.1 - 9 6.3 25.9 24 4.9 25.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-C3HC4_3 PF13920.6 ORY97804.1 - 2e-14 53.2 9.8 3.1e-14 52.6 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY97804.1 - 6.9e-06 26.3 11.0 1.1e-05 25.6 11.0 1.3 1 0 0 1 1 1 1 Ring finger domain Armet PF10208.9 ORY97804.1 - 2.2e-05 24.4 1.2 0.19 11.7 0.0 2.8 3 0 0 3 3 2 2 Degradation arginine-rich protein for mis-folding zf-C3HC4_2 PF13923.6 ORY97804.1 - 7e-05 22.6 12.2 0.00012 21.9 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY97804.1 - 0.0015 18.4 10.3 0.0031 17.3 10.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Peptidase_S15 PF02129.18 ORY97804.1 - 0.0017 18.0 5.7 0.0038 16.9 5.7 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) zf-C3HC4 PF00097.25 ORY97804.1 - 0.0033 17.3 12.2 0.006 16.4 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY97804.1 - 0.0095 15.9 11.4 0.019 14.9 11.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY97804.1 - 0.011 15.9 8.9 0.04 14.1 9.1 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc_ribbon_2 PF13240.6 ORY97804.1 - 0.011 15.4 2.8 0.015 15.0 0.9 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-P11 PF03854.14 ORY97804.1 - 0.024 14.3 8.2 0.045 13.4 8.2 1.3 1 0 0 1 1 1 0 P-11 zinc finger Presenilin PF01080.17 ORY97804.1 - 0.026 13.3 16.8 0.029 13.1 16.8 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 ORY97804.1 - 0.072 11.6 10.8 0.091 11.2 10.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Sin_N PF04801.13 ORY97804.1 - 0.09 12.0 28.9 0.14 11.3 28.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region SAP PF02037.27 ORY97804.1 - 0.17 11.7 1.4 31 4.4 0.0 3.1 3 0 0 3 3 3 0 SAP domain SOBP PF15279.6 ORY97804.1 - 0.34 11.5 24.3 0.44 11.1 24.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein HeH PF12949.7 ORY97804.1 - 0.39 10.5 2.8 0.73 9.6 0.4 2.3 2 0 0 2 2 2 0 HeH/LEM domain GREB1 PF15782.5 ORY97804.1 - 0.54 7.3 17.6 0.71 6.9 17.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 ORY97804.1 - 0.86 7.8 32.5 0.99 7.6 32.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4776 PF16003.5 ORY97804.1 - 0.9 8.5 23.4 0.16 11.0 19.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) zf-RING_4 PF14570.6 ORY97804.1 - 1.3 8.9 10.1 3.3 7.6 10.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain CDC45 PF02724.14 ORY97804.1 - 1.4 7.2 22.9 2.1 6.6 22.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 ORY97804.1 - 1.7 6.6 17.2 2.1 6.4 17.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.11 ORY97804.1 - 2.2 8.3 16.0 3.8 7.5 16.0 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4551 PF15087.6 ORY97804.1 - 2.3 6.9 21.9 3.1 6.5 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4175 PF13779.6 ORY97804.1 - 2.4 5.9 37.9 3.2 5.5 37.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.12 ORY97804.1 - 2.8 7.7 17.9 5 6.9 17.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DZR PF12773.7 ORY97804.1 - 3.2 7.8 8.8 7.2 6.7 8.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon RecR PF02132.15 ORY97804.1 - 4.8 6.8 8.3 24 4.6 0.1 2.4 2 0 0 2 2 2 0 RecR protein DUF4569 PF15133.6 ORY97804.1 - 5.3 6.7 22.6 11 5.6 22.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Neur_chan_memb PF02932.16 ORY97804.1 - 6.1 6.8 18.4 12 5.9 18.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MG2 PF01835.19 ORY97805.1 - 0.082 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 MG2 domain DUF4708 PF15813.5 ORY97805.1 - 0.17 11.0 0.1 0.23 10.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) Exo_endo_phos PF03372.23 ORY97806.1 - 5e-05 22.9 0.1 6.1e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ORY97806.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase GATase_4 PF13230.6 ORY97807.1 - 2.3e-19 69.3 0.0 2.9e-18 65.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 ORY97807.1 - 4.5e-10 39.8 0.0 8.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain WD40 PF00400.32 ORY97808.1 - 1.8e-10 41.2 1.6 0.037 14.9 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY97808.1 - 1.2e-08 35.1 0.0 0.0013 19.0 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY97808.1 - 0.0026 17.7 0.0 0.068 13.0 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY97808.1 - 0.0069 15.7 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain Hira PF07569.11 ORY97808.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split WD40 PF00400.32 ORY97809.1 - 2.5e-19 69.2 4.5 0.00088 20.0 0.7 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY97809.1 - 4.3e-10 39.7 0.0 0.00035 20.8 0.0 4.1 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY97809.1 - 0.00013 22.0 0.0 0.021 14.7 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY97809.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 ORY97809.1 - 0.081 11.9 0.2 14 4.6 0.0 2.8 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMR_HSR1 PF01926.23 ORY97811.1 - 9.5e-15 54.7 0.1 3.8e-13 49.5 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY97811.1 - 0.00053 19.9 0.1 0.007 16.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ORY97811.1 - 0.00058 19.4 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY97811.1 - 0.0025 17.9 2.1 0.11 12.6 0.0 3.3 4 0 0 4 4 4 1 Dynamin family Halogen_Hydrol PF10112.9 ORY97811.1 - 0.0087 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein GTP_EFTU PF00009.27 ORY97811.1 - 0.02 14.5 0.3 0.65 9.5 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORY97811.1 - 0.023 14.0 0.0 0.062 12.6 0.0 1.7 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 ORY97811.1 - 0.059 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 ORY97811.1 - 0.12 12.1 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation VHS PF00790.19 ORY97812.1 - 4.1e-13 49.4 0.4 4.1e-13 49.4 0.4 1.6 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 ORY97812.1 - 4.3e-06 26.9 0.2 4.3e-06 26.9 0.2 2.2 2 1 0 2 2 2 1 GAT domain DUF1810 PF08837.11 ORY97812.1 - 0.11 12.3 0.2 0.18 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) DUF2457 PF10446.9 ORY97812.1 - 1.6 7.8 17.4 0.53 9.4 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Oxidored_FMN PF00724.20 ORY97814.1 - 1.8e-69 234.6 0.0 2.2e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UNC-93 PF05978.16 ORY97814.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 TP_methylase PF00590.20 ORY97815.1 - 5.8e-43 147.3 0.0 1e-42 146.5 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 ORY97815.1 - 3.5e-20 71.4 0.2 6.9e-20 70.5 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 ORY97815.1 - 3.5e-18 66.0 0.2 8.7e-18 64.7 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 ORY97815.1 - 1.7e-10 40.1 0.3 3.5e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Acyltransf_C PF16076.5 ORY97816.1 - 6.9e-19 67.7 0.2 1.7e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 ORY97816.1 - 2.7e-14 52.9 0.3 1.9e-12 47.0 0.6 2.5 2 1 0 2 2 2 1 Acyltransferase GYF PF02213.16 ORY97816.1 - 0.12 12.0 0.4 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 GYF domain LtrA PF06772.11 ORY97817.1 - 1e-39 136.8 33.2 6.6e-39 134.1 33.2 1.9 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Ycf70 PF17382.2 ORY97817.1 - 0.14 12.6 1.1 0.44 11.0 1.1 1.9 1 0 0 1 1 1 0 Uncharacterized Ycf70-like HAP1_N PF04849.13 ORY97818.1 - 3.7e-05 23.1 0.2 3.7e-05 23.1 0.2 2.3 2 0 0 2 2 2 1 HAP1 N-terminal conserved region BLOC1_2 PF10046.9 ORY97818.1 - 0.0033 17.7 11.5 0.2 12.0 0.1 2.9 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 T3SSipB PF16535.5 ORY97818.1 - 0.068 13.6 10.0 0.061 13.8 6.1 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB HMMR_N PF15905.5 ORY97818.1 - 1.9 7.9 23.9 7.4 5.9 10.2 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Med9 PF07544.13 ORY97818.1 - 4.1 7.6 20.2 2 8.6 5.7 3.5 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4559 PF15112.6 ORY97818.1 - 7.5 6.1 12.1 16 5.0 12.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FUSC PF04632.12 ORY97818.1 - 8.1 4.8 9.2 12 4.2 9.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 ORY97818.1 - 8.9 6.5 29.5 5.4 7.2 11.2 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 AAA_12 PF13087.6 ORY97819.1 - 1.9e-40 138.6 0.0 5.3e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ORY97819.1 - 1.6e-28 100.3 3.7 1.1e-13 51.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ORY97819.1 - 5.7e-11 42.9 0.0 4.9e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY97819.1 - 1.6e-08 34.5 0.0 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 ORY97819.1 - 0.00049 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 ORY97819.1 - 0.0016 18.5 0.1 0.0035 17.4 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 ORY97819.1 - 0.0082 15.4 0.4 0.29 10.3 0.1 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 ORY97819.1 - 0.0096 15.7 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 ORY97819.1 - 0.04 13.4 7.5 0.067 12.7 4.6 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Spore_III_AF PF09581.10 ORY97819.1 - 0.045 13.8 0.4 0.25 11.3 0.4 2.2 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) AAA_18 PF13238.6 ORY97819.1 - 0.11 13.0 0.4 1.2 9.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY97819.1 - 0.17 12.2 0.0 0.74 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M20 PF01546.28 ORY97820.1 - 8.7e-31 107.2 0.0 1.1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY97820.1 - 4.5e-11 42.6 0.0 8.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.25 ORY97821.1 - 1.3e-23 83.7 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97821.1 - 1.9e-09 37.2 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY97821.1 - 2.6e-08 33.1 0.8 3.4e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY97821.1 - 0.00073 19.5 1.2 0.063 13.2 0.0 3.1 2 1 0 3 3 3 1 Phosphotransferase enzyme family Spt20 PF12090.8 ORY97821.1 - 9.3 5.8 8.8 15 5.1 8.8 1.2 1 0 0 1 1 1 0 Spt20 family RicinB_lectin_2 PF14200.6 ORY97823.1 - 1.2e-10 41.9 0.0 7.4e-05 23.4 0.0 2.4 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ORY97823.1 - 1.6e-08 34.8 0.0 3.8e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain p450 PF00067.22 ORY97824.1 - 1.7e-73 248.0 0.3 2.2e-73 247.6 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4867 PF16161.5 ORY97824.1 - 0.028 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4867) Ribosomal_S13_N PF08069.12 ORY97825.1 - 2.1e-31 107.7 0.4 3.5e-31 107.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORY97825.1 - 2e-13 50.3 0.4 2.7e-13 49.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Arm PF00514.23 ORY97827.1 - 7.6e-75 244.9 25.6 5.1e-12 45.4 0.1 10.3 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY97827.1 - 2.9e-20 72.4 14.7 0.00016 22.1 0.2 8.9 8 2 1 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 ORY97827.1 - 3.3e-17 62.7 12.8 6.9e-07 29.6 0.1 6.6 3 3 3 6 6 6 5 HEAT repeats Adaptin_N PF01602.20 ORY97827.1 - 1.1e-13 50.6 8.6 1.2e-10 40.6 0.4 2.2 1 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 ORY97827.1 - 3.1e-13 48.7 13.9 0.18 12.1 0.0 8.7 8 0 0 8 8 8 3 HEAT repeat KAP PF05804.12 ORY97827.1 - 2.2e-11 42.7 2.5 3.2e-11 42.1 2.5 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 ORY97827.1 - 7.3e-11 42.0 4.4 1e-06 28.4 1.1 2.8 1 1 0 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 ORY97827.1 - 1.5e-07 31.0 4.0 0.0015 17.9 0.6 2.7 1 1 2 3 3 3 3 V-ATPase subunit H DUF3361 PF11841.8 ORY97827.1 - 2.6e-07 30.7 3.3 0.052 13.5 0.1 3.5 2 1 1 3 3 3 3 Domain of unknown function (DUF3361) Cnd1 PF12717.7 ORY97827.1 - 9.4e-06 25.8 7.2 0.2 11.7 0.1 4.5 2 2 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 ORY97827.1 - 5.8e-05 23.2 6.4 0.75 9.9 0.2 5.2 4 1 3 7 7 7 3 V-ATPase subunit H UNC45-central PF11701.8 ORY97827.1 - 0.006 16.6 4.8 3.5 7.6 0.1 4.4 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 ORY97827.1 - 0.011 15.9 1.5 4.5 7.5 0.0 3.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RTTN_N PF14726.6 ORY97827.1 - 0.032 15.0 1.7 0.3 11.9 0.0 3.0 3 1 0 3 3 2 0 Rotatin, an armadillo repeat protein, centriole functioning HEAT_PBS PF03130.16 ORY97827.1 - 0.081 13.6 10.0 1.2e+02 3.8 0.0 7.3 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 ORY97827.1 - 0.09 12.8 6.2 0.24 11.4 0.2 3.6 2 2 2 4 4 4 0 Spinocerebellar ataxia type 10 protein domain PH PF00169.29 ORY97828.1 - 0.032 14.7 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Glyco_hydro_16 PF00722.21 ORY97829.1 - 1e-31 109.8 0.2 1.5e-31 109.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 QCR10 PF09796.9 ORY97830.1 - 1.1e-16 60.7 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UreD PF01774.17 ORY97831.1 - 9.3e-56 189.1 0.1 1.1e-55 188.9 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein MID_pPIWI_RE PF18157.1 ORY97831.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 2 0 0 2 2 2 0 MID domain of pPIWI_RE Kinesin PF00225.23 ORY97832.1 - 1.2e-94 317.0 0.1 1.6e-94 316.6 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY97832.1 - 1e-23 83.9 0.0 2.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding RNase_P_Rpp14 PF01900.19 ORY97834.1 - 2.2e-08 34.3 0.0 2.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DNA_repr_REX1B PF14966.6 ORY97835.1 - 0.021 15.4 0.7 0.05 14.3 0.1 2.0 2 0 0 2 2 2 0 DNA repair REX1-B AATF-Che1 PF13339.6 ORY97835.1 - 0.15 12.8 2.4 4.4 8.0 0.0 3.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor COX6B PF02297.17 ORY97836.1 - 1.6e-20 73.1 7.7 1.9e-20 72.8 7.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 ORY97836.1 - 0.00082 19.3 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like C-terminal domain WD40 PF00400.32 ORY97837.1 - 8.2e-14 51.8 23.5 0.0033 18.2 1.7 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.6 ORY97837.1 - 5.1e-11 42.6 3.7 1.1e-07 31.7 1.4 3.0 2 1 1 3 3 3 2 PQQ-like domain WD40_like PF17005.5 ORY97837.1 - 3e-06 26.8 0.0 0.39 10.0 0.0 3.3 1 1 2 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 ORY97837.1 - 4.1e-06 27.0 0.6 1.9 8.8 0.2 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 ORY97837.1 - 4.4e-05 23.2 4.2 0.0081 16.1 0.1 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat Nup160 PF11715.8 ORY97837.1 - 0.0006 18.6 2.8 0.37 9.4 0.0 3.1 3 1 0 3 3 3 2 Nucleoporin Nup120/160 F-box-like PF12937.7 ORY97837.1 - 0.00096 19.0 0.3 0.0023 17.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like PQQ_3 PF13570.6 ORY97837.1 - 0.0022 18.4 14.5 1.9 9.1 0.1 4.7 4 1 0 4 4 4 2 PQQ-like domain Thiolase_N PF00108.23 ORY97838.1 - 1.1e-79 267.4 4.6 1.1e-79 267.4 4.6 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY97838.1 - 1.2e-46 157.4 0.1 3.3e-46 155.9 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ORY97838.1 - 0.017 15.0 1.4 3.1 7.7 0.2 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ORY97838.1 - 1.1 8.8 8.8 0.08 12.5 1.5 2.5 3 1 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain tRNA_anti-codon PF01336.25 ORY97843.1 - 1e-08 35.1 0.1 3.6e-08 33.3 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 ORY97843.1 - 0.0017 17.3 0.2 0.0026 16.8 0.2 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Linker_histone PF00538.19 ORY97843.1 - 0.06 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family CDC24_OB3 PF17244.2 ORY97843.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Mob1_phocein PF03637.17 ORY97844.1 - 1.8e-34 119.2 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mpp10 PF04006.12 ORY97844.1 - 0.79 8.1 17.0 1.1 7.6 17.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 ORY97844.1 - 0.96 7.6 21.4 1.3 7.2 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 ORY97844.1 - 0.96 8.4 14.6 1.3 7.9 14.6 1.1 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 ORY97844.1 - 2.7 8.3 20.3 4.2 7.7 20.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 ORY97844.1 - 6.3 4.8 33.2 9.1 4.2 33.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi WES_acyltransf PF03007.16 ORY97845.1 - 1.3e-18 67.7 0.5 1.6e-14 54.3 0.4 2.4 2 1 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ORY97845.1 - 2.6e-16 59.9 0.0 4.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 ORY97845.1 - 0.049 12.3 0.0 0.074 11.7 0.0 1.3 1 0 0 1 1 1 0 Condensation domain Transferase PF02458.15 ORY97845.1 - 0.088 11.4 0.0 0.7 8.5 0.0 1.9 2 0 0 2 2 2 0 Transferase family CitMHS PF03600.16 ORY97846.1 - 5.1e-17 62.0 34.4 5.1e-17 62.0 34.4 3.4 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.15 ORY97846.1 - 9.1e-17 61.5 28.2 5.7e-10 39.1 3.1 2.5 2 1 1 3 3 3 2 Arsenical pump membrane protein DEAD PF00270.29 ORY97848.1 - 8.3e-47 159.2 0.0 1.6e-45 155.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY97848.1 - 1.3e-30 106.0 0.0 4.6e-30 104.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 ORY97849.1 - 0.00058 19.7 14.9 0.0024 17.7 11.4 2.8 2 1 0 2 2 2 1 PHD-finger zf-MYST PF17772.1 ORY97849.1 - 0.0098 15.5 0.2 0.024 14.2 0.2 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain zf-met PF12874.7 ORY97849.1 - 0.052 14.0 0.2 0.052 14.0 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY97849.1 - 0.086 13.1 0.4 0.086 13.1 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Axin_b-cat_bind PF08833.10 ORY97849.1 - 0.12 12.5 2.9 0.38 10.9 2.9 1.9 1 0 0 1 1 1 0 Axin beta-catenin binding domain Spindle_Spc25 PF08234.12 ORY97850.1 - 5.3e-17 61.8 0.0 1e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Atg14 PF10186.9 ORY97850.1 - 0.00066 18.9 6.2 0.00091 18.4 6.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_MT_bd PF06657.13 ORY97850.1 - 0.0048 17.3 2.9 0.68 10.4 4.0 3.0 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 V_ATPase_I PF01496.19 ORY97850.1 - 0.087 10.7 2.5 0.093 10.6 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5105 PF17118.5 ORY97850.1 - 0.12 12.1 1.7 0.21 11.4 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5105) CREPT PF16566.5 ORY97850.1 - 0.24 11.6 10.7 0.062 13.5 6.7 2.0 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF874 PF05917.11 ORY97850.1 - 0.54 9.2 15.5 1 8.4 8.5 2.0 1 1 1 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) APG6_N PF17675.1 ORY97850.1 - 0.84 10.2 17.5 5.3 7.6 17.3 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region ACR_tran PF00873.19 ORY97850.1 - 1.9 6.0 5.0 2.2 5.8 5.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Fib_alpha PF08702.10 ORY97850.1 - 2.1 8.6 10.6 1.4 9.1 6.6 2.4 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family SPATA1_C PF15743.5 ORY97850.1 - 2.2 8.4 13.3 0.48 10.5 6.2 2.6 3 0 0 3 3 3 0 Spermatogenesis-associated C-terminus Leu_zip PF15294.6 ORY97850.1 - 2.6 7.5 12.1 3.2 7.2 3.4 1.9 1 1 1 2 2 2 0 Leucine zipper RebB PF11747.8 ORY97850.1 - 2.6 8.2 7.5 7.4 6.8 0.3 2.3 2 0 0 2 2 2 0 Killing trait DUF4407 PF14362.6 ORY97850.1 - 2.9 7.2 15.6 4 6.7 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 ORY97850.1 - 3.9 6.3 17.4 7.9 5.3 17.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Herpes_UL25 PF01499.16 ORY97850.1 - 4.9 5.5 9.3 8.3 4.8 9.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1664 PF07889.12 ORY97850.1 - 5.1 7.2 11.8 1.5 8.9 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 ORY97850.1 - 6.9 7.0 11.9 1.1 9.5 7.1 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ANAPC4_WD40 PF12894.7 ORY97851.1 - 0.0026 18.0 0.0 4.9 7.5 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY97851.1 - 0.035 15.0 0.3 73 4.5 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORY97851.1 - 0.16 10.9 0.0 14 4.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SH3_1 PF00018.28 ORY97853.1 - 6.6e-17 60.8 0.0 1.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY97853.1 - 1e-16 60.5 0.1 1.6e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY97853.1 - 1.2e-13 50.5 0.0 2.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain HCV_NS5a_1a PF08300.13 ORY97854.1 - 0.038 14.1 1.5 0.065 13.4 1.5 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain ChaC PF04752.12 ORY97855.1 - 1.6e-66 223.8 0.0 1.9e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF4038 PF13204.6 ORY97855.1 - 0.022 14.4 0.2 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4038) Utp21 PF04192.12 ORY97857.1 - 3.8e-68 229.5 1.0 6.3e-68 228.8 1.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 ORY97857.1 - 8.2e-27 92.9 18.4 3e-08 34.2 0.5 8.9 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY97857.1 - 1.9e-19 69.8 0.6 0.00039 20.7 0.0 7.9 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY97857.1 - 1.6e-07 31.4 0.1 0.074 12.9 0.0 4.1 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY97857.1 - 6.7e-07 28.9 0.4 0.0095 15.3 0.0 3.7 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 ORY97857.1 - 6.5e-06 25.1 5.7 0.32 9.6 0.0 5.0 2 2 2 5 5 5 3 Nucleoporin Nup120/160 HPS3_N PF14761.6 ORY97857.1 - 0.00016 21.3 0.0 0.14 11.7 0.0 3.7 4 1 1 5 5 5 1 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.11 ORY97857.1 - 0.022 13.5 1.1 2.3 6.9 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Helveticin_J PF17312.2 ORY97857.1 - 0.07 12.2 0.0 0.21 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacteriocin helveticin-J Ge1_WD40 PF16529.5 ORY97857.1 - 0.17 10.8 0.9 9.9 5.0 0.0 3.9 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ACBP PF00887.19 ORY97858.1 - 1.5e-27 95.6 1.0 6.4e-27 93.6 0.3 2.2 2 0 0 2 2 2 1 Acyl CoA binding protein PRIMA1 PF16101.5 ORY97858.1 - 0.03 14.3 0.0 0.03 14.3 0.0 2.8 1 1 2 3 3 3 0 Proline-rich membrane anchor 1 DUF4763 PF15960.5 ORY97858.1 - 0.11 11.8 0.2 10 5.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF4637 PF15470.6 ORY97858.1 - 1.2 8.9 4.2 1.9 8.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF974 PF06159.13 ORY97859.1 - 2.5e-75 253.5 0.2 2.5e-75 253.5 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.7 ORY97859.1 - 5.7e-13 49.0 4.6 9.6e-07 28.5 0.0 3.6 3 1 1 4 4 4 3 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 ORY97859.1 - 9.9e-05 22.4 0.1 0.0075 16.4 0.0 2.6 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain DUF2722 PF10846.8 ORY97859.1 - 0.0015 17.5 4.3 0.0021 17.1 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) ASH PF15780.5 ORY97859.1 - 0.022 15.0 0.4 0.29 11.3 0.2 2.4 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF3464 PF11947.8 ORY97859.1 - 0.088 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Spt20 PF12090.8 ORY97859.1 - 2.1 7.9 21.0 4.3 6.9 21.0 1.4 1 0 0 1 1 1 0 Spt20 family DUF5336 PF17270.2 ORY97859.1 - 7 6.2 8.0 12 5.5 8.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF4449 PF14613.6 ORY97860.1 - 2.9e-13 50.3 0.4 2.9e-13 50.3 0.4 3.6 3 1 2 5 5 5 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 ORY97860.1 - 0.0079 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain TetR_C_11 PF16859.5 ORY97860.1 - 0.085 13.2 0.3 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain UPF0149 PF03695.13 ORY97860.1 - 0.19 12.0 2.7 0.97 9.7 1.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0149) EamA PF00892.20 ORY97862.1 - 2.6e-29 102.1 39.2 1.1e-16 61.2 14.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ORY97862.1 - 1.2 8.5 10.5 1.8 7.8 3.6 2.7 1 1 1 2 2 2 0 Triose-phosphate Transporter family LsmAD PF06741.13 ORY97863.1 - 1.8e-26 92.5 0.5 1.8e-26 92.5 0.5 2.5 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 ORY97863.1 - 3.1e-19 68.9 0.0 6.4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1690 PF07956.11 ORY97863.1 - 0.053 14.0 0.9 0.12 12.8 0.9 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) PAM2 PF07145.15 ORY97863.1 - 0.17 11.6 8.1 1.9 8.3 0.6 3.2 2 1 1 3 3 3 0 Ataxin-2 C-terminal region Arrestin_N PF00339.29 ORY97864.1 - 1.7e-05 24.9 0.1 0.00068 19.7 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY97864.1 - 0.0025 18.3 0.0 0.0035 17.8 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain GST_N_3 PF13417.6 ORY97865.1 - 3.2e-09 37.1 0.0 1.3e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY97865.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY97865.1 - 3.6e-07 30.3 0.0 5.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY97865.1 - 9.8e-07 28.7 0.1 2e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY97865.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY97865.1 - 4.8e-05 23.6 0.0 0.00022 21.5 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain CK2S PF15011.6 ORY97866.1 - 0.00016 21.6 1.0 0.00042 20.2 0.9 1.8 1 1 0 1 1 1 1 Casein Kinase 2 substrate HAUS-augmin3 PF14932.6 ORY97866.1 - 0.003 17.2 1.3 0.0038 16.8 1.3 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Prefoldin PF02996.17 ORY97866.1 - 0.0042 17.0 3.3 0.0042 17.0 3.3 2.0 2 0 0 2 2 2 1 Prefoldin subunit Mt_ATP-synt_D PF05873.12 ORY97866.1 - 0.0085 16.0 3.5 0.061 13.2 1.4 2.1 1 1 1 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) DASH_Duo1 PF08651.10 ORY97866.1 - 0.0089 15.8 1.4 0.19 11.5 0.4 2.5 2 0 0 2 2 2 1 DASH complex subunit Duo1 FlxA PF14282.6 ORY97866.1 - 0.015 15.2 3.2 0.026 14.5 3.2 1.3 1 0 0 1 1 1 0 FlxA-like protein Fib_alpha PF08702.10 ORY97866.1 - 0.044 14.0 1.3 0.15 12.3 0.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Terminase_2 PF03592.16 ORY97866.1 - 0.06 13.8 0.0 0.081 13.4 0.0 1.1 1 0 0 1 1 1 0 Terminase small subunit FlgN PF05130.12 ORY97866.1 - 0.064 13.8 6.6 1.6 9.3 7.1 2.6 2 1 0 2 2 2 0 FlgN protein ETC_C1_NDUFA5 PF04716.14 ORY97866.1 - 0.068 13.0 1.3 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 ETC complex I subunit conserved region Osmo_CC PF08946.10 ORY97866.1 - 0.068 13.4 1.4 0.15 12.3 1.4 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Synaptobrevin PF00957.21 ORY97866.1 - 0.078 12.8 2.8 0.1 12.4 1.2 1.9 2 0 0 2 2 2 0 Synaptobrevin Fzo_mitofusin PF04799.13 ORY97866.1 - 0.094 12.3 3.1 0.085 12.4 1.2 1.7 2 0 0 2 2 2 0 fzo-like conserved region DUF3540 PF12059.8 ORY97866.1 - 0.12 12.2 1.2 3 7.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) BLOC1_2 PF10046.9 ORY97866.1 - 0.16 12.3 3.3 0.28 11.5 1.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_Gp19 PF09355.10 ORY97866.1 - 0.2 12.1 0.7 0.5 10.8 0.2 1.9 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 T2SSM PF04612.12 ORY97866.1 - 0.41 10.7 3.1 0.27 11.3 1.4 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M ECM11 PF15463.6 ORY97866.1 - 0.54 10.8 4.1 0.28 11.7 1.0 2.0 2 0 0 2 2 2 0 Extracellular mutant protein 11 Cor1 PF04803.12 ORY97866.1 - 0.69 10.1 9.1 14 5.9 9.1 2.2 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region SlyX PF04102.12 ORY97866.1 - 5.3 7.7 8.2 1 10.0 2.7 2.4 3 0 0 3 3 2 0 SlyX UNC45-central PF11701.8 ORY97867.1 - 1.4e-24 86.7 0.1 1.4e-24 86.7 0.1 3.2 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central TPR_9 PF13371.6 ORY97867.1 - 0.0056 16.8 0.4 0.02 15.0 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY97867.1 - 0.033 14.8 0.1 0.2 12.4 0.1 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY97867.1 - 0.087 13.0 0.0 0.36 11.1 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat YebO PF13974.6 ORY97867.1 - 0.11 12.6 2.7 0.39 10.8 0.1 3.2 2 0 0 2 2 2 0 YebO-like protein HEAT PF02985.22 ORY97867.1 - 0.12 12.7 5.5 20 5.8 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat K_trans PF02705.16 ORY97867.1 - 0.18 10.3 0.0 0.32 9.4 0.0 1.3 1 0 0 1 1 1 0 K+ potassium transporter Fis1_TPR_C PF14853.6 ORY97867.1 - 1.4 9.0 3.6 0.81 9.8 0.2 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Aldo_ket_red PF00248.21 ORY97868.1 - 1.5e-52 178.6 0.0 2e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ntox47 PF15540.6 ORY97868.1 - 0.17 12.2 0.0 58 4.0 0.0 3.3 3 0 0 3 3 3 0 Bacterial toxin 47 SCAI PF12070.8 ORY97869.1 - 6.8e-186 619.2 0.1 8.4e-186 619.0 0.1 1.1 1 0 0 1 1 1 1 Protein SCAI Adaptin_binding PF10199.9 ORY97869.1 - 0.097 13.3 2.3 0.82 10.3 1.5 2.4 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4770 PF15994.5 ORY97869.1 - 0.46 10.7 12.3 0.24 11.6 9.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Peptidase_M36 PF02128.15 ORY97870.1 - 8.9e-153 508.8 6.8 1.1e-152 508.5 6.8 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 ORY97870.1 - 1.2e-15 57.1 1.0 2.8e-15 55.9 1.0 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 ORY97870.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Ovate PF04844.13 ORY97871.1 - 0.093 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Transcriptional repressor, ovate TBCC PF07986.12 ORY97874.1 - 1.3e-24 86.3 0.1 2.8e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 ORY97874.1 - 8.8e-19 68.1 0.6 1.3e-18 67.5 0.6 1.2 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DUF3080 PF11279.8 ORY97874.1 - 0.0062 15.8 0.1 0.0087 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) Tektin PF03148.14 ORY97874.1 - 0.024 13.4 0.4 0.034 12.9 0.4 1.2 1 0 0 1 1 1 0 Tektin family Pox_A_type_inc PF04508.12 ORY97874.1 - 0.23 11.4 0.6 0.52 10.3 0.1 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat IDO PF01231.18 ORY97875.1 - 2.2e-44 152.0 0.0 2.6e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Peptidase_M22 PF00814.25 ORY97876.1 - 1.2e-85 287.6 0.0 1.3e-85 287.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family YAcAr PF10686.9 ORY97876.1 - 0.046 13.7 0.1 8.5 6.4 0.0 3.2 3 1 1 4 4 4 0 YspA, cpYpsA-related SLOG family Carbam_trans_N PF02543.15 ORY97876.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus RhoGEF PF00621.20 ORY97878.1 - 1.8e-38 132.6 0.3 2.1e-38 132.4 0.3 1.0 1 0 0 1 1 1 1 RhoGEF domain NAD_binding_10 PF13460.6 ORY97879.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 1 1 2 2 2 0 NAD(P)H-binding Mad3_BUB1_I PF08311.12 ORY97880.1 - 1.1e-40 138.5 1.5 1.7e-40 137.8 1.5 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 ORY97880.1 - 1.9e-06 28.0 0.0 3.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein zf-H2C2_2 PF13465.6 ORY97881.1 - 5.1e-07 29.8 2.4 5.1e-07 29.8 2.4 3.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY97881.1 - 3.4e-06 27.2 16.3 0.00047 20.5 4.5 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type SLY PF12485.8 ORY97881.1 - 0.012 16.3 0.6 0.022 15.5 0.1 1.6 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein zf-C2H2_4 PF13894.6 ORY97881.1 - 0.013 16.2 14.0 0.049 14.5 3.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY97881.1 - 0.034 14.3 0.8 0.056 13.6 0.8 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger Arf PF00025.21 ORY97882.1 - 5.6e-77 257.1 0.1 6.5e-77 256.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY97882.1 - 2.3e-15 56.9 0.1 3.3e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY97882.1 - 1.2e-13 51.0 0.1 1.4e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY97882.1 - 1.8e-13 50.4 0.5 6.6e-09 35.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY97882.1 - 6.7e-12 45.2 0.0 7.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY97882.1 - 4.9e-10 39.2 0.0 5.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY97882.1 - 2.8e-06 27.4 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY97882.1 - 5.1e-05 22.9 0.2 0.00047 19.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 ORY97882.1 - 0.0023 18.5 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORY97882.1 - 0.0034 17.3 0.1 0.52 10.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 ORY97882.1 - 0.0065 16.1 0.5 1.2 8.7 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORY97882.1 - 0.011 15.7 0.2 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 ORY97882.1 - 0.038 14.5 0.6 0.12 12.8 0.6 1.8 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORY97882.1 - 0.086 12.6 0.2 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain Nup35_RRM_2 PF14605.6 ORY97883.1 - 5.1e-08 32.8 0.2 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 ORY97883.1 - 4.3e-05 23.3 1.6 8.8e-05 22.3 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ORY97883.1 - 0.00014 21.6 0.9 0.15 11.9 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 ORY97883.1 - 0.0006 19.8 2.3 0.0012 18.8 2.3 1.6 1 0 0 1 1 1 1 Zinc finger domain Tsc35 PF15079.6 ORY97883.1 - 0.0089 15.6 3.0 0.0089 15.6 3.0 2.0 2 0 0 2 2 2 1 Testis-specific protein 35 PWI PF01480.17 ORY97883.1 - 0.011 16.0 0.0 0.085 13.2 0.0 2.4 2 0 0 2 2 2 0 PWI domain DUF2868 PF11067.8 ORY97883.1 - 8 5.9 7.6 18 4.7 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Ribosomal_L27A PF00828.19 ORY97884.1 - 1.6e-38 132.3 0.0 2.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Slx4 PF09494.10 ORY97884.1 - 0.0081 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease CotH PF08757.11 ORY97885.1 - 2.6e-38 132.3 2.1 4.5e-38 131.6 2.1 1.3 1 0 0 1 1 1 1 CotH kinase protein CoA_transf_3 PF02515.17 ORY97886.1 - 6.9e-41 140.6 0.0 4.2e-36 124.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III TFIIB PF00382.19 ORY97887.1 - 3.2e-44 148.8 0.9 5.1e-24 84.1 0.6 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ORY97887.1 - 1e-14 53.7 0.6 1.7e-14 53.1 0.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 ORY97887.1 - 0.00052 20.0 1.3 0.00098 19.2 1.3 1.6 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 ORY97887.1 - 0.0013 18.8 0.1 0.43 10.7 0.0 2.5 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 ORY97887.1 - 0.0096 15.7 0.7 0.49 10.2 0.2 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain RMI1_N PF08585.12 ORY97888.1 - 4.3e-31 108.4 0.0 4.3e-31 108.4 0.0 2.4 2 1 0 2 2 2 1 RecQ mediated genome instability protein GDP_Man_Dehyd PF16363.5 ORY97889.1 - 8.6e-162 538.2 0.0 9.8e-162 538.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY97889.1 - 8e-75 251.4 0.0 1e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY97889.1 - 2.9e-07 29.9 0.0 4.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY97889.1 - 3.5e-05 23.1 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY97889.1 - 0.021 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ATP-synt_S1 PF05827.12 ORY97890.1 - 2.9e-06 27.2 0.1 5.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) TcdB_toxin_midN PF12256.8 ORY97890.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Gti1_Pac2 PF09729.9 ORY97891.1 - 8.2e-46 156.4 6.2 1.1e-39 136.4 0.6 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family PEPCK_ATP PF01293.20 ORY97892.1 - 6.2e-224 743.9 0.0 7.2e-224 743.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 ORY97892.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PQQ_2 PF13360.6 ORY97893.1 - 4.2e-16 59.2 0.0 3.1e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 ORY97893.1 - 1.7e-12 46.6 0.7 0.0053 16.6 0.0 4.4 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.6 ORY97893.1 - 7.3e-09 35.8 0.1 0.028 14.9 0.0 5.1 5 0 0 5 5 5 2 PQQ-like domain Ubiquitin_4 PF18036.1 ORY97894.1 - 1.7e-23 82.5 0.1 9.4e-23 80.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 ORY97894.1 - 0.023 14.5 2.1 0.24 11.2 0.7 2.7 2 2 0 2 2 2 0 Ubiquitin family Aminotran_1_2 PF00155.21 ORY97896.1 - 2.5e-89 300.0 0.0 2.8e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MPC PF03650.13 ORY97897.1 - 2.4e-39 133.9 0.7 2.6e-39 133.8 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Sec20 PF03908.13 ORY97898.1 - 3.4e-21 75.0 1.7 3.4e-21 75.0 1.7 2.2 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 ORY97898.1 - 0.017 14.5 7.3 0.03 13.7 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L30_N PF08079.12 ORY97898.1 - 0.059 13.6 1.6 0.17 12.1 1.6 1.8 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Sugar_tr PF00083.24 ORY97899.1 - 3.6e-43 148.1 32.3 2.1e-22 79.6 13.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY97899.1 - 6.5e-16 58.2 44.6 2.6e-08 33.2 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY97899.1 - 0.00018 20.2 27.5 0.00073 18.2 12.8 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein GCR1_C PF12550.8 ORY97900.1 - 2.6e-19 69.3 0.3 4.3e-19 68.6 0.3 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes IFT57 PF10498.9 ORY97900.1 - 0.00031 19.8 0.8 0.00043 19.4 0.8 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 TRAF_BIRC3_bd PF16673.5 ORY97900.1 - 0.0021 17.8 1.0 0.004 16.9 1.0 1.4 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain DUF948 PF06103.11 ORY97900.1 - 0.015 15.6 1.4 0.015 15.6 1.4 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ORC6 PF05460.13 ORY97900.1 - 0.02 14.2 4.7 0.034 13.4 4.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nup54 PF13874.6 ORY97900.1 - 0.032 14.3 0.6 0.061 13.4 0.6 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4515 PF14988.6 ORY97900.1 - 0.064 13.1 1.1 0.095 12.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) MbeD_MobD PF04899.12 ORY97900.1 - 0.08 13.1 2.3 0.21 11.7 2.3 1.8 1 0 0 1 1 1 0 MbeD/MobD like SlyX PF04102.12 ORY97900.1 - 0.09 13.4 2.5 0.36 11.5 2.9 1.8 2 0 0 2 2 1 0 SlyX Vps52 PF04129.12 ORY97900.1 - 0.092 11.5 0.4 0.14 10.9 0.4 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family ADIP PF11559.8 ORY97900.1 - 0.16 12.0 3.2 0.29 11.2 3.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 ORY97900.1 - 0.42 10.4 2.4 0.9 9.3 2.4 1.5 1 0 0 1 1 1 0 Septum formation initiator P_C PF06640.11 ORY97900.1 - 1.1 9.4 8.6 1.6 8.8 8.6 1.3 1 0 0 1 1 1 0 P protein C-terminus RRM_1 PF00076.22 ORY97901.1 - 2.3e-16 59.4 0.1 3.5e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 ORY97901.1 - 1.5e-08 34.3 3.4 2.6e-08 33.6 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ORY97901.1 - 0.00063 19.5 1.2 0.0011 18.7 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORY97901.1 - 0.0022 17.7 1.8 0.0042 16.8 1.8 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Nup35_RRM_2 PF14605.6 ORY97901.1 - 0.0024 17.8 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY97901.1 - 0.017 15.1 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif zf-CCHC_3 PF13917.6 ORY97901.1 - 0.04 13.9 0.5 0.04 13.9 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 ORY97901.1 - 0.2 11.4 1.0 0.49 10.2 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle NCBP3 PF10309.9 ORY97902.1 - 2.8e-21 75.1 0.0 4.7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Gag_p17 PF00540.18 ORY97902.1 - 0.029 14.4 0.1 0.059 13.3 0.0 1.5 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) RhoGEF PF00621.20 ORY97904.1 - 6.2e-37 127.6 4.0 6.2e-37 127.6 4.0 1.7 2 0 0 2 2 2 1 RhoGEF domain IFRD PF05004.13 ORY97905.1 - 3.6e-57 193.8 2.2 3.6e-57 193.8 2.2 1.6 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) DASH_Spc19 PF08287.11 ORY97907.1 - 7.5e-15 55.2 7.9 8.7e-15 55.0 7.9 1.1 1 0 0 1 1 1 1 Spc19 DUF2408 PF10303.9 ORY97907.1 - 0.01 16.4 5.0 0.013 16.0 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Tnp_22_trimer PF17489.2 ORY97907.1 - 0.063 13.3 0.5 0.063 13.3 0.5 2.1 2 1 0 2 2 2 0 L1 transposable element trimerization domain TMF_DNA_bd PF12329.8 ORY97907.1 - 0.19 11.7 8.8 0.32 11.0 2.8 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NUC PF18510.1 ORY97907.1 - 0.42 11.0 4.1 0.75 10.2 4.0 1.4 1 1 0 1 1 1 0 Nuclease domain p450 PF00067.22 ORY97909.1 - 1.2e-77 261.6 0.0 1.4e-77 261.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.19 ORY97910.1 - 1.3e-40 139.5 0.3 1.6e-39 136.0 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain Miga PF10265.9 ORY97910.1 - 5.6 5.8 8.6 0.48 9.3 3.6 1.9 2 0 0 2 2 2 0 Mitoguardin NUDIX PF00293.28 ORY97911.1 - 5.6e-07 29.7 0.0 7.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AAA_16 PF13191.6 ORY97913.1 - 9.9e-23 81.4 0.7 8.4e-22 78.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Response_reg PF00072.24 ORY97913.1 - 1.5e-20 73.4 0.0 4.2e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY97913.1 - 8.8e-17 60.9 0.0 5.1e-16 58.5 0.0 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 ORY97913.1 - 2.3e-14 53.9 0.4 2.7e-13 50.4 0.4 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 ORY97913.1 - 1.1e-09 38.7 0.0 2.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ORY97913.1 - 3.1e-08 34.3 0.0 1.3e-07 32.4 0.0 2.2 2 0 0 2 2 1 1 GAF domain Pkinase PF00069.25 ORY97913.1 - 8e-07 28.7 0.0 0.00012 21.5 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain NACHT PF05729.12 ORY97913.1 - 4.6e-06 26.7 0.1 3.8e-05 23.7 0.1 2.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 ORY97913.1 - 3.3e-05 23.2 0.0 0.00012 21.4 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 ORY97913.1 - 0.00066 19.6 0.2 0.0016 18.4 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase GAF_3 PF13492.6 ORY97913.1 - 0.00079 19.8 0.0 0.0029 17.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain ABC_tran PF00005.27 ORY97913.1 - 0.0017 18.9 0.3 0.044 14.3 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 ORY97913.1 - 0.0018 18.0 0.3 0.0081 15.9 0.2 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY97913.1 - 0.0037 17.5 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_MalT PF17874.1 ORY97913.1 - 0.016 14.6 4.7 0.038 13.4 1.3 2.9 3 0 0 3 3 3 0 MalT-like TPR region Pkinase_Tyr PF07714.17 ORY97913.1 - 0.016 14.5 0.0 6.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase MeaB PF03308.16 ORY97913.1 - 0.038 13.0 0.1 0.16 11.0 0.3 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 ORY97913.1 - 0.074 13.5 0.3 0.27 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2564 PF10819.8 ORY97913.1 - 0.096 13.1 1.7 0.94 9.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) NTPase_1 PF03266.15 ORY97913.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 NTPase Methyltransf_11 PF08241.12 ORY97914.1 - 3.7e-20 72.4 0.0 6.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY97914.1 - 2.6e-18 66.4 0.0 4.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY97914.1 - 8e-16 58.5 0.1 1.8e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY97914.1 - 6.9e-14 52.4 0.0 1e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY97914.1 - 3.7e-12 46.3 0.0 5.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY97914.1 - 9.7e-09 34.9 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ORY97914.1 - 1.3e-06 28.0 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 ORY97914.1 - 1.2e-05 24.8 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ORY97914.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ORY97914.1 - 0.01 15.4 0.1 0.031 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 ORY97914.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 ORY97914.1 - 0.035 14.1 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ABC1 PF03109.16 ORY97915.1 - 2.8e-32 111.4 0.0 5.1e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family PBP PF01161.20 ORY97916.1 - 1.1e-18 67.9 0.6 1.5e-18 67.4 0.6 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LINES_N PF14694.6 ORY97917.1 - 6.4e-12 45.6 3.0 6.4e-12 45.6 3.0 1.9 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.6 ORY97917.1 - 0.0021 17.5 2.2 0.0066 15.9 0.0 2.7 3 0 0 3 3 3 1 Lines C-terminus JTB PF05439.12 ORY97919.1 - 3.6e-12 46.3 6.3 4.6e-11 42.7 6.3 2.1 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) SKG6 PF08693.10 ORY97919.1 - 0.035 13.5 2.1 0.066 12.6 2.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PAP2_3 PF14378.6 ORY97919.1 - 0.12 12.0 0.1 3 7.5 0.0 2.0 2 0 0 2 2 2 0 PAP2 superfamily Chitin_synth_1 PF01644.17 ORY97920.1 - 1.3e-74 249.6 0.5 2.1e-74 249.0 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY97920.1 - 1.2e-27 95.6 0.2 3.7e-27 94.1 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY97920.1 - 1.4e-20 73.4 0.2 6.7e-16 58.0 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY97920.1 - 0.0022 18.0 9.2 0.0022 18.0 9.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 HNH PF01844.23 ORY97921.1 - 0.0051 17.0 2.5 0.012 15.8 2.5 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 ORY97921.1 - 0.15 12.2 0.2 0.4 10.9 0.2 1.7 1 1 0 1 1 1 0 HNH endonuclease Amino_oxidase PF01593.24 ORY97922.1 - 5e-54 184.3 0.0 6.7e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY97922.1 - 2.7e-08 33.9 0.0 6.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY97922.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY97922.1 - 0.13 11.5 0.1 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY97922.1 - 0.2 11.2 0.1 0.53 9.8 0.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Abhydrolase_6 PF12697.7 ORY97923.1 - 1.3e-08 35.7 1.7 1.3e-08 35.7 0.2 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY97923.1 - 0.00042 20.0 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY97923.1 - 0.0041 16.4 0.0 0.02 14.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ORY97923.1 - 0.011 15.6 0.1 0.31 10.9 0.1 2.4 1 1 0 1 1 1 0 Serine hydrolase DUF99 PF01949.16 ORY97923.1 - 0.038 13.4 0.0 7.8 5.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF99 Ndr PF03096.14 ORY97923.1 - 0.13 11.0 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family AMP-binding PF00501.28 ORY97924.1 - 9.8e-101 337.4 0.0 1.3e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY97924.1 - 9.5e-06 26.5 0.1 3e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Response_reg PF00072.24 ORY97925.1 - 1.4e-24 86.4 0.3 2.6e-24 85.5 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Macoilin PF09726.9 ORY97925.1 - 0.76 8.3 1.8 1 7.8 1.8 1.1 1 0 0 1 1 1 0 Macoilin family HSF_DNA-bind PF00447.17 ORY97926.1 - 2.4e-31 108.2 1.6 2.4e-31 108.2 1.6 1.8 2 1 0 2 2 2 1 HSF-type DNA-binding WDCP PF15390.6 ORY97926.1 - 0.072 11.5 12.2 0.11 10.8 10.9 1.8 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family FAM76 PF16046.5 ORY97926.1 - 0.28 10.5 8.5 0.39 10.0 8.5 1.1 1 0 0 1 1 1 0 FAM76 protein LMBR1 PF04791.16 ORY97926.1 - 0.35 9.7 4.7 0.39 9.6 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF16 PF01519.16 ORY97926.1 - 3.9 8.0 8.9 9.5 6.8 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DAD PF02109.16 ORY97927.1 - 1.8e-43 147.3 7.4 2e-43 147.1 7.4 1.0 1 0 0 1 1 1 1 DAD family Transferase PF02458.15 ORY97928.1 - 3.4e-19 68.8 0.0 6.1e-19 68.0 0.0 1.4 1 1 0 1 1 1 1 Transferase family Coa1 PF08695.10 ORY97929.1 - 1.5e-25 89.2 0.0 2e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Chalcone_2 PF16035.5 ORY97930.1 - 3.8e-41 141.1 1.3 3.9e-40 137.8 1.3 2.0 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 ORY97930.1 - 2.4e-09 37.5 2.2 8.3e-07 29.3 2.2 2.2 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 ORY97930.1 - 4.6e-05 22.9 0.1 6.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase GDPD_2 PF13653.6 ORY97930.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Proteasome PF00227.26 ORY97931.1 - 2.8e-39 134.6 0.0 3.3e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NAC PF01849.18 ORY97932.1 - 1.9e-19 69.4 0.4 2.5e-18 65.8 0.0 2.4 2 0 0 2 2 2 1 NAC domain TT_ORF2 PF02957.15 ORY97932.1 - 0.033 15.1 0.9 0.033 15.1 0.9 1.7 2 0 0 2 2 2 0 TT viral ORF2 MscS_TM PF12794.7 ORY97932.1 - 0.77 8.5 1.9 1.5 7.6 1.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF501 PF04417.12 ORY97934.1 - 0.013 15.3 1.2 0.013 15.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF4600 PF15372.6 ORY97934.1 - 0.014 15.8 2.2 0.014 15.8 2.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4600) DUF4193 PF13834.6 ORY97934.1 - 3 8.4 6.7 11 6.6 2.4 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4193) DIRP PF06584.13 ORY97934.1 - 8.3 6.7 11.0 24 5.2 0.2 3.4 2 1 1 3 3 3 0 DIRP DUF1043 PF06295.12 ORY97934.1 - 8.8 6.4 15.1 0.41 10.6 7.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1043) TYW3 PF02676.14 ORY97935.1 - 3.5e-57 193.2 0.0 4.8e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 PKK PF12474.8 ORY97935.1 - 0.0034 17.5 9.7 0.0054 16.9 9.7 1.2 1 0 0 1 1 1 1 Polo kinase kinase UPF0121 PF03661.13 ORY97936.1 - 2.5e-36 125.3 10.7 3e-36 125.0 10.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) PIH1 PF08190.12 ORY97937.1 - 6.6e-27 94.0 0.0 1.1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 ORY97937.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 PIH1 CS-like domain PPR_2 PF13041.6 ORY97938.1 - 1.5e-05 25.1 0.0 6.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 ORY97938.1 - 0.0047 17.1 0.1 0.58 10.5 0.0 2.8 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.7 ORY97938.1 - 0.033 13.9 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 PPR repeat Peptidase_S8 PF00082.22 ORY97939.1 - 4.2e-45 154.3 5.5 7.5e-45 153.4 5.5 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 ORY97939.1 - 2.9e-09 36.8 1.3 2.9e-09 36.8 1.3 2.0 2 0 0 2 2 2 1 PA domain fn3_5 PF06280.12 ORY97939.1 - 1.8e-07 31.8 0.0 5.7e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Fn3-like domain Monooxygenase_B PF04744.12 ORY97939.1 - 0.099 11.5 0.0 0.29 10.0 0.0 1.6 2 0 0 2 2 2 0 Monooxygenase subunit B protein Thioredoxin PF00085.20 ORY97940.1 - 1.2e-30 105.6 0.0 1.4e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY97940.1 - 1.6e-06 28.5 0.2 9.4e-06 26.0 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY97940.1 - 3.9e-05 23.9 0.0 6.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 ORY97940.1 - 5.5e-05 22.7 0.0 6.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 ORY97940.1 - 0.00019 21.2 0.0 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 ORY97940.1 - 0.00022 21.1 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ORY97940.1 - 0.00057 20.0 0.0 0.00084 19.5 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 ORY97940.1 - 0.00086 18.3 0.0 0.00098 18.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 ORY97940.1 - 0.0011 18.7 0.1 0.0017 18.1 0.0 1.4 1 1 0 1 1 1 1 Redoxin TraF PF13728.6 ORY97940.1 - 0.095 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein OrfB_Zn_ribbon PF07282.11 ORY97943.1 - 5.5e-06 26.2 0.0 7.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY97944.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain CPSase_L_D2 PF02786.17 ORY97946.1 - 2.1e-76 256.1 0.1 4.1e-76 255.2 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY97946.1 - 7.8e-46 155.2 0.1 3.1e-45 153.3 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY97946.1 - 6.9e-38 129.1 0.0 2.7e-37 127.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY97946.1 - 2.1e-16 59.5 1.1 2.1e-16 59.5 1.1 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY97946.1 - 2e-10 40.6 0.2 5.3e-10 39.2 0.2 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY97946.1 - 5.5e-06 26.0 0.2 2.1e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY97946.1 - 4.2e-05 23.6 0.1 0.00013 22.1 0.1 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY97946.1 - 7.6e-05 22.5 0.1 0.0069 16.2 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.19 ORY97946.1 - 0.00033 20.5 0.1 0.00066 19.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 ORY97946.1 - 0.00034 20.3 0.0 0.00094 18.8 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 ORY97946.1 - 0.026 15.2 0.3 8.1 7.2 0.0 3.4 3 0 0 3 3 3 0 HlyD family secretion protein ATPgrasp_ST PF14397.6 ORY97946.1 - 0.03 13.6 0.0 0.073 12.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 ORY97946.1 - 0.12 12.0 0.1 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain SGT1 PF07093.11 ORY97948.1 - 2.8e-120 402.5 24.7 4.5e-119 398.5 24.7 2.4 1 1 0 1 1 1 1 SGT1 protein Mo25 PF08569.11 ORY97948.1 - 0.14 11.5 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 Mo25-like FAM176 PF14851.6 ORY97948.1 - 6.4 6.4 13.9 5.3 6.7 3.7 2.6 2 0 0 2 2 2 0 FAM176 family SAP PF02037.27 ORY97949.1 - 4.7e-10 39.0 0.7 9.5e-10 38.0 0.7 1.5 1 0 0 1 1 1 1 SAP domain DUF3474 PF11960.8 ORY97949.1 - 0.23 11.6 7.8 0.76 10.0 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Lin-8 PF03353.15 ORY97949.1 - 0.66 9.5 37.2 0.85 9.1 14.1 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 ORY97949.1 - 2.2 8.4 21.6 0.11 12.7 5.2 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF5563 PF17718.1 ORY97949.1 - 3.7 7.1 7.4 11 5.5 7.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5563) Band_3_cyto PF07565.13 ORY97949.1 - 4.8 6.9 21.1 1.4 8.6 6.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 ORY97949.1 - 5.2 5.9 28.3 0.88 8.5 11.2 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 ORY97949.1 - 5.7 5.9 23.1 0.55 9.2 6.0 2.3 2 0 0 2 2 2 0 Solute carrier family 12 COG5 PF10392.9 ORY97950.1 - 3.3e-29 101.7 2.1 3.3e-29 101.7 2.1 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 ORY97950.1 - 1.2e-07 31.7 0.3 1.2e-07 31.7 0.3 3.1 2 1 1 3 3 3 1 Vps51/Vps67 DUF1351 PF07083.11 ORY97950.1 - 0.00022 21.0 0.0 0.044 13.6 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1351) Vps54_N PF10475.9 ORY97950.1 - 0.00059 19.2 5.5 0.00087 18.7 0.6 2.9 2 2 1 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 ORY97950.1 - 0.0032 17.5 3.1 0.0034 17.5 0.9 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 HSBP1 PF06825.12 ORY97950.1 - 0.045 13.6 0.0 16 5.4 0.0 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Bacillus_HBL PF05791.11 ORY97950.1 - 0.083 12.7 4.1 0.36 10.6 2.2 2.6 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Sec5 PF15469.6 ORY97950.1 - 0.12 12.2 2.1 0.93 9.3 2.2 2.4 1 1 0 1 1 1 0 Exocyst complex component Sec5 ArnB_C PF18677.1 ORY97950.1 - 0.3 11.2 2.4 2.6 8.2 0.1 3.4 3 1 1 4 4 4 0 Archaellum regulatory network B, C-terminal domain FlaC_arch PF05377.11 ORY97950.1 - 2.8 8.4 10.5 4.6 7.7 0.1 4.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 ORY97950.1 - 3.2 5.6 8.9 0.97 7.3 3.1 2.1 1 1 0 2 2 2 0 Prominin RNase_PH PF01138.21 ORY97951.1 - 9.8e-34 116.7 0.1 1.7e-33 115.9 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY97951.1 - 0.00039 20.4 0.2 0.0011 18.9 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RPN13_C PF16550.5 ORY97952.1 - 4.2e-32 110.6 3.1 4.2e-32 110.6 3.1 2.3 1 1 1 2 2 2 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 ORY97952.1 - 2.1e-30 105.1 0.0 3.5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor zf-C3HC4_3 PF13920.6 ORY97953.1 - 0.029 14.2 0.5 0.072 13.0 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2184 PF09950.9 ORY97953.1 - 0.062 12.7 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) dUTPase PF00692.19 ORY97954.1 - 2.2e-45 153.5 0.0 2.5e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 dUTPase Pkinase PF00069.25 ORY97955.1 - 9.5e-27 94.0 0.0 1.2e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97955.1 - 1.6e-12 47.2 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY97955.1 - 2.8e-09 36.2 0.4 3.9e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Med1 PF10744.9 ORY97956.1 - 1.4e-39 136.3 0.0 2.5e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 PX PF00787.24 ORY97957.1 - 1.4e-19 70.1 0.7 4.1e-19 68.6 0.7 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ORY97957.1 - 6.2e-10 39.0 14.0 6.6e-06 25.8 3.6 2.3 2 0 0 2 2 2 2 Vps5 C terminal like ER PF01133.17 ORY97957.1 - 0.0061 16.6 0.3 0.5 10.4 0.0 2.9 2 0 0 2 2 2 1 Enhancer of rudimentary DUF2250 PF10007.9 ORY97957.1 - 0.041 14.0 0.7 0.12 12.5 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) MobC PF05713.11 ORY97957.1 - 0.051 14.1 0.2 0.17 12.4 0.2 1.9 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) GLYCAM-1 PF05242.11 ORY97957.1 - 0.17 12.0 3.3 2.2 8.4 0.1 2.9 2 1 1 3 3 3 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) RP-C_C PF11800.8 ORY97957.1 - 0.28 11.3 5.1 0.15 12.2 2.4 1.9 1 1 1 2 2 2 0 Replication protein C C-terminal region GPS2_interact PF15784.5 ORY97957.1 - 0.4 11.1 6.6 0.11 13.0 1.0 2.9 2 2 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain Sec8_exocyst PF04048.14 ORY97957.1 - 1.4 8.8 9.3 0.77 9.6 2.5 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Peptidase_C10 PF01640.17 ORY97957.1 - 2.3 8.5 5.3 0.57 10.5 0.5 2.0 2 0 0 2 2 2 0 Peptidase C10 family DEAD PF00270.29 ORY97959.1 - 2.4e-28 99.1 0.0 4.9e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 ORY97959.1 - 2e-19 70.1 1.2 5.9e-19 68.6 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 ORY97959.1 - 3e-15 56.5 0.0 3.9e-14 52.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY97959.1 - 6.2e-07 29.6 0.0 4.4e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RPN13_C PF16550.5 ORY97959.1 - 0.087 13.0 0.6 32 4.7 0.0 3.4 4 0 0 4 4 4 0 UCH-binding domain Zip PF02535.22 ORY97960.1 - 3.3e-27 95.6 15.5 4.6e-27 95.1 15.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2500 PF10694.9 ORY97960.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF1129 PF06570.11 ORY97960.1 - 4 6.9 11.9 1.1 8.7 0.4 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) SelP_N PF04592.14 ORY97960.1 - 8.3 5.7 17.0 12 5.2 17.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2085 PF09858.9 ORY97960.1 - 10 6.7 10.1 28 5.3 0.3 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) Pkinase PF00069.25 ORY97961.1 - 4.8e-76 255.6 0.0 6.5e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY97961.1 - 4.9e-39 134.2 0.0 6.9e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY97961.1 - 3e-06 26.8 1.3 8.5e-06 25.3 1.3 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY97961.1 - 1e-05 25.6 5.3 0.0033 17.4 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY97961.1 - 8.3e-05 22.0 0.0 0.00024 20.5 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Choline_kinase PF01633.20 ORY97961.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ORY97961.1 - 0.0018 17.9 0.1 0.0031 17.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY97961.1 - 0.017 14.0 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 ORY97961.1 - 0.12 11.8 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Alginate_lyase PF05426.12 ORY97962.1 - 2.2e-63 214.4 1.8 2.5e-63 214.2 1.8 1.0 1 0 0 1 1 1 1 Alginate lyase TPR_8 PF13181.6 ORY97962.1 - 0.014 15.6 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.16 ORY97963.1 - 4e-35 121.4 22.7 4e-35 121.4 22.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3844 PF12955.7 ORY97964.1 - 8.4e-13 48.4 6.3 1.8e-12 47.3 6.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_3 PF12947.7 ORY97964.1 - 0.14 12.4 8.4 0.23 11.7 8.4 1.3 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.13 ORY97964.1 - 0.43 11.0 13.4 0.78 10.2 13.4 1.4 1 0 0 1 1 1 0 EGF-like domain SPC22 PF04573.12 ORY97965.1 - 6.5e-46 155.9 0.0 7.6e-46 155.7 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit SDH_alpha PF03313.15 ORY97966.1 - 2.4e-105 351.9 0.6 3e-105 351.6 0.6 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ORY97966.1 - 5.4e-58 195.8 0.0 1.1e-57 194.7 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain FAS_I_H PF18314.1 ORY97966.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain MBOAT PF03062.19 ORY97967.1 - 0.047 13.0 0.2 0.047 13.0 0.2 1.0 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Fungal_trans PF04082.18 ORY97968.1 - 7.5e-16 58.0 0.1 1.4e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY97968.1 - 7.6e-09 35.5 10.9 1.6e-08 34.5 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.14 ORY97969.1 - 1.6e-05 24.3 28.4 2.3e-05 23.8 28.4 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Metallophos PF00149.28 ORY97970.1 - 6.5e-14 52.9 0.2 1.3e-13 51.9 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L23eN PF03939.13 ORY97971.1 - 1.2e-22 79.9 13.6 2.2e-22 79.0 13.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORY97971.1 - 4.5e-15 55.8 5.5 5e-15 55.6 1.2 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 OrfB_Zn_ribbon PF07282.11 ORY97973.1 - 2.8e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY97974.1 - 0.0023 17.8 0.1 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DUF4383 PF14325.6 ORY97975.1 - 0.043 14.1 1.3 0.37 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) MIG-14_Wnt-bd PF06664.12 ORY97975.1 - 0.15 11.3 4.8 0.2 10.8 4.8 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion TMEM132D_C PF15706.5 ORY97975.1 - 0.69 9.7 0.1 0.69 9.7 0.1 2.0 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term E1-E2_ATPase PF00122.20 ORY97975.1 - 0.84 9.1 3.1 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 E1-E2 ATPase EphA2_TM PF14575.6 ORY97975.1 - 2.5 9.1 4.6 16 6.5 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SPC25 PF06703.11 ORY97975.1 - 4.9 6.9 5.2 1.8 8.3 0.7 2.1 1 1 2 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PTPS PF01242.19 ORY97976.1 - 4.4e-34 117.1 0.3 5.2e-34 116.9 0.3 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF3271 PF11675.8 ORY97976.1 - 0.031 13.5 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Ribosomal_L19e PF01280.20 ORY97977.1 - 1.4e-62 210.0 10.1 1.4e-62 210.0 10.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e CNH PF00780.22 ORY97978.1 - 1.7e-43 149.2 0.0 3.1e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY97978.1 - 2.2e-31 109.5 0.1 4e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY97978.1 - 1.7e-14 54.1 0.0 6.3e-14 52.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORY97978.1 - 7.5e-10 38.7 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 ORY97978.1 - 0.13 12.8 0.0 0.44 11.1 0.0 2.0 1 0 0 1 1 1 0 PH domain CCDC53 PF10152.9 ORY97978.1 - 0.59 10.5 3.1 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HpcH_HpaI PF03328.14 ORY97979.1 - 3.5e-35 121.1 0.2 7.7e-35 120.0 0.1 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ORY97979.1 - 3.3e-13 49.5 0.0 5.6e-12 45.5 0.0 2.0 1 1 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 ORY97979.1 - 0.00054 19.0 0.3 0.00074 18.5 0.3 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Peptidase_S8 PF00082.22 ORY97980.1 - 1.3e-38 133.0 6.4 2.1e-38 132.3 6.4 1.3 1 0 0 1 1 1 1 Subtilase family Peripla_BP_6 PF13458.6 ORY97980.1 - 0.0081 15.9 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 Periplasmic binding protein DUF3731 PF12531.8 ORY97980.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.4 2 0 0 2 2 2 0 DNA-K related protein TPR_2 PF07719.17 ORY97981.1 - 7.7e-17 60.0 4.0 1.5e-07 30.9 0.2 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY97981.1 - 4.8e-11 42.0 4.5 3.3e-08 33.0 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY97981.1 - 5.1e-08 32.5 2.4 1.3e-05 24.7 0.1 3.9 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 ORY97981.1 - 1e-07 31.6 2.7 0.0019 18.3 0.1 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY97981.1 - 2.8e-07 30.8 9.8 0.007 17.1 0.0 6.9 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY97981.1 - 8.8e-07 29.1 10.2 0.00058 20.1 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY97981.1 - 1.5e-05 24.7 2.3 0.0017 18.2 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY97981.1 - 1.8e-05 24.4 0.2 0.0084 16.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY97981.1 - 0.00011 22.3 4.2 0.037 14.2 0.1 5.0 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY97981.1 - 0.0003 21.2 0.1 12 6.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY97981.1 - 0.00054 20.2 0.3 4.6 7.8 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY97981.1 - 0.0015 19.1 0.1 0.047 14.4 0.0 4.8 6 1 1 7 7 5 2 Tetratricopeptide repeat DUF2205 PF10224.9 ORY97981.1 - 0.46 10.5 4.1 0.74 9.9 0.8 2.7 2 0 0 2 2 2 0 Short coiled-coil protein CPSase_L_D2 PF02786.17 ORY97983.1 - 5.5e-65 218.8 0.0 1.2e-64 217.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 ORY97983.1 - 2e-36 124.4 0.0 4.4e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 ORY97983.1 - 1.7e-23 83.3 0.1 3.4e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 ORY97983.1 - 3e-08 33.5 0.0 6.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 ORY97983.1 - 1.7e-06 27.8 0.0 4.5e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 ORY97983.1 - 6.3e-06 25.9 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY97983.1 - 1.6e-05 25.0 0.0 5.8e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 ORY97983.1 - 0.013 15.6 1.4 0.18 12.0 0.5 2.9 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 ATPgrasp_ST PF14397.6 ORY97983.1 - 0.042 13.1 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 ORY97983.1 - 0.12 12.3 0.1 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein Pkinase_Tyr PF07714.17 ORY97985.1 - 7.4e-19 68.0 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY97985.1 - 1.7e-18 66.9 0.0 3.8e-18 65.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 ORY97985.1 - 0.00054 19.6 0.3 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORY97985.1 - 0.0011 19.0 1.2 0.0035 17.3 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family DEAD PF00270.29 ORY97986.1 - 2.7e-46 157.6 0.0 6.1e-46 156.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY97986.1 - 1.2e-28 99.6 0.0 4.5e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY97986.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Tyr_Deacylase PF02580.16 ORY97987.1 - 3e-54 183.4 0.3 3.4e-54 183.3 0.3 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TelA PF05816.11 ORY97990.1 - 0.0022 17.1 0.6 0.004 16.3 0.6 1.3 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) THOC7 PF05615.13 ORY97990.1 - 0.0043 17.3 2.8 0.011 16.0 2.8 1.7 1 0 0 1 1 1 1 Tho complex subunit 7 Radical_SAM_N PF08497.10 ORY97990.1 - 0.2 10.9 1.5 0.21 10.8 0.2 1.7 2 0 0 2 2 2 0 Radical SAM N-terminal DASH_Spc34 PF08657.10 ORY97990.1 - 0.3 10.9 7.8 0.29 10.9 4.0 2.6 2 1 0 2 2 2 0 DASH complex subunit Spc34 DivIC PF04977.15 ORY97990.1 - 7.2 6.5 6.7 28 4.6 5.6 2.4 1 1 1 2 2 2 0 Septum formation initiator Mito_fiss_reg PF05308.11 ORY97991.1 - 0.0057 16.8 0.5 0.0057 16.8 0.5 1.8 2 0 0 2 2 2 1 Mitochondrial fission regulator MerR-DNA-bind PF09278.11 ORY97991.1 - 0.2 12.2 1.4 1.3 9.6 0.1 2.4 2 1 0 2 2 2 0 MerR, DNA binding Ras PF00071.22 ORY97992.1 - 1.4e-58 197.1 0.1 1.8e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY97992.1 - 1.6e-36 125.2 0.1 2.9e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY97992.1 - 1.1e-15 57.6 0.1 1.4e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY97992.1 - 2.7e-06 27.1 0.1 1.8e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY97992.1 - 3.8e-06 26.4 0.1 5.5e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY97992.1 - 3.5e-05 23.9 0.0 7.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY97992.1 - 4.6e-05 22.9 0.1 5.7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY97992.1 - 6e-05 23.0 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY97992.1 - 0.002 17.7 0.1 0.069 12.7 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 ORY97992.1 - 0.044 13.2 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 ORY97992.1 - 0.051 13.3 0.2 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY97992.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SurE PF01975.17 ORY97993.1 - 2.6e-48 164.4 0.0 3.5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Metallophos PF00149.28 ORY97994.1 - 2.2e-35 123.0 0.1 2.8e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY97994.1 - 0.025 15.0 0.1 0.052 14.0 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ORY97994.1 - 0.053 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 ORY97994.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Sugar_tr PF00083.24 ORY97995.1 - 5.5e-110 368.3 22.9 6.3e-110 368.1 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY97995.1 - 1.8e-24 86.3 34.1 3e-17 62.6 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 ORY97995.1 - 0.18 12.1 5.4 3.5 7.9 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) FAD-oxidase_C PF02913.19 ORY97996.1 - 3.4e-67 226.7 0.0 6.1e-67 225.9 0.1 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY97996.1 - 9.8e-38 129.0 0.0 2.2e-37 127.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Macoilin PF09726.9 ORY97996.1 - 3.5 6.1 5.7 4.5 5.7 5.7 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_3_C PF01915.22 ORY97997.1 - 2.2e-63 213.9 0.0 3.5e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY97997.1 - 1.5e-39 136.3 0.0 2.6e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY97997.1 - 3.9e-22 78.1 0.0 7.9e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain BTB PF00651.31 ORY97999.1 - 1e-20 74.0 0.1 5.5e-13 49.1 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain CAP_GLY PF01302.25 ORY97999.1 - 1.9e-18 66.2 0.1 3.3e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Nup35_RRM PF05172.13 ORY98000.1 - 5.9e-11 42.2 0.1 3.1e-10 39.9 0.1 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 ORY98000.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 ORY98000.1 - 0.3 11.0 10.3 0.53 10.2 10.4 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF866 PF05907.13 ORY98001.1 - 6.3e-60 201.6 0.0 7.1e-60 201.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Lipase3_N PF03893.16 ORY98001.1 - 0.13 12.3 0.0 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Lipase 3 N-terminal region Aminotran_1_2 PF00155.21 ORY98002.1 - 2.1e-40 139.0 0.0 2.6e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY98002.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase TFA2_Winged_2 PF18121.1 ORY98003.1 - 7.8e-20 70.3 0.2 1.6e-19 69.4 0.2 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 ORY98003.1 - 6e-16 58.5 0.0 1.8e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF5563 PF17718.1 ORY98004.1 - 0.038 13.5 2.9 0.046 13.3 2.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5563) IF3_N PF05198.16 ORY98005.1 - 4.9e-12 46.0 0.2 9.4e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 ORY98005.1 - 7.3e-11 41.9 0.1 1.1e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 ORY98005.1 - 3e-05 23.8 5.5 6.2e-05 22.7 5.5 1.5 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Peptidase_S9 PF00326.21 ORY98006.1 - 5e-40 137.2 0.2 7.7e-40 136.6 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 ORY98006.1 - 0.00033 19.6 0.2 0.0012 17.7 0.0 2.1 2 1 1 3 3 3 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AXE1 PF05448.12 ORY98006.1 - 0.00036 19.3 0.0 0.029 13.1 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Lactonase PF10282.9 ORY98006.1 - 0.00059 19.2 0.2 0.0033 16.7 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Abhydrolase_1 PF00561.20 ORY98006.1 - 0.00097 18.9 2.3 0.0021 17.7 1.5 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY98006.1 - 0.013 14.4 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family FSH1 PF03959.13 ORY98007.1 - 4e-57 193.3 0.0 4.6e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORY98007.1 - 4.7e-05 23.3 0.1 0.0025 17.6 0.1 2.6 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY98007.1 - 0.041 13.2 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 OPT PF03169.15 ORY98008.1 - 2e-155 518.9 13.8 2.3e-155 518.7 13.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3382 PF11862.8 ORY98008.1 - 0.025 14.8 0.3 0.025 14.8 0.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) SET PF00856.28 ORY98009.1 - 5.2e-12 46.5 0.0 4.8e-11 43.3 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY98009.1 - 3.8e-05 23.7 9.1 3.8e-05 23.7 9.1 3.3 2 1 0 2 2 2 1 MYND finger TPR_12 PF13424.6 ORY98009.1 - 0.05 13.9 0.2 7.3 7.0 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat DZR PF12773.7 ORY98009.1 - 0.3 11.2 17.3 0.097 12.7 3.6 3.4 2 1 0 2 2 2 0 Double zinc ribbon ADK_lid PF05191.14 ORY98009.1 - 0.68 10.0 7.6 17 5.5 0.0 3.9 3 1 0 3 3 3 0 Adenylate kinase, active site lid Siva PF05458.12 ORY98009.1 - 0.85 9.3 10.9 0.052 13.2 5.3 1.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-Mss51 PF13824.6 ORY98009.1 - 1.9 8.7 18.5 0.17 12.0 3.8 4.0 3 1 1 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc-ribbons_6 PF07191.12 ORY98009.1 - 5.2 7.1 21.3 1.5 8.9 1.8 3.3 3 0 0 3 3 3 0 zinc-ribbons PUF PF00806.19 ORY98010.1 - 3.5e-68 221.6 16.1 6.4e-08 31.9 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Peptidase_M28 PF04389.17 ORY98011.1 - 1.9e-45 155.0 0.0 2.5e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY98011.1 - 6e-09 35.8 0.1 1.3e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORY98011.1 - 4.2e-05 23.4 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORY98011.1 - 0.026 13.5 0.0 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase GDPD PF03009.17 ORY98012.1 - 1.9e-61 208.0 0.0 4e-61 207.0 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 ORY98012.1 - 3.6e-29 101.2 4.6 1.4e-15 57.6 0.3 3.5 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 ORY98012.1 - 2.8e-22 80.2 10.8 2.5e-10 40.8 0.2 4.1 2 1 2 4 4 4 3 SPX domain Ank_4 PF13637.6 ORY98012.1 - 2.4e-20 72.6 4.8 5e-07 30.1 0.0 4.9 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY98012.1 - 2.5e-18 64.3 6.7 0.0057 17.1 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 ORY98012.1 - 1.2e-13 51.0 5.7 8.5e-05 22.8 0.2 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY98012.1 - 9.6e-13 48.0 11.8 0.0075 16.7 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat UreF PF01730.16 ORY98012.1 - 0.048 14.3 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 UreF SMK-1 PF04802.15 ORY98013.1 - 2e-69 233.3 7.2 3.7e-69 232.4 7.2 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SDA1 PF05285.12 ORY98013.1 - 0.1 12.0 16.5 0.054 12.9 11.7 2.1 2 0 0 2 2 2 0 SDA1 FAD-oxidase_C PF02913.19 ORY98014.1 - 2.8e-51 174.6 0.0 4e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY98014.1 - 1.8e-31 108.7 0.0 3.3e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Kelch_4 PF13418.6 ORY98015.1 - 7.4e-25 86.7 4.7 3.5e-08 33.3 0.1 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY98015.1 - 3.6e-24 83.8 3.7 7.9e-07 28.8 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 ORY98015.1 - 5.2e-24 83.6 6.4 7.6e-07 28.6 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 ORY98015.1 - 1.6e-23 82.2 5.4 1.1e-05 25.2 0.0 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 ORY98015.1 - 1.7e-21 75.7 9.3 6.9e-05 23.0 0.1 5.5 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 ORY98015.1 - 2.2e-19 69.2 9.7 2.1e-05 24.7 0.0 6.0 5 1 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 ORY98015.1 - 4.1e-15 56.0 0.0 1e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain PCI PF01399.27 ORY98016.1 - 2e-13 50.7 0.2 1.1e-12 48.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain Rpn9_C PF18261.1 ORY98016.1 - 0.0014 18.2 1.3 0.0014 18.2 1.3 1.9 2 0 0 2 2 2 1 Rpn9 C-terminal helix Npun_R1517 PF18068.1 ORY98016.1 - 0.078 13.3 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 Npun R1517 NPV_P10 PF05531.12 ORY98016.1 - 3.2 8.3 5.5 13 6.3 0.1 3.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ILVD_EDD PF00920.21 ORY98017.1 - 2.8e-217 722.4 1.4 3.2e-217 722.2 1.4 1.0 1 0 0 1 1 1 1 Dehydratase family UBA PF00627.31 ORY98018.1 - 2.4e-11 43.3 0.3 8.6e-11 41.5 0.3 2.0 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 ORY98018.1 - 2.4e-11 43.2 0.0 3.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY98018.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY98018.1 - 0.00013 22.5 1.0 0.00043 20.8 0.0 2.4 3 0 0 3 3 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY98018.1 - 0.00017 21.7 0.0 0.00063 19.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 ORY98018.1 - 0.00066 19.6 5.7 0.00066 19.6 5.7 3.7 3 1 2 5 5 5 2 STI1 domain HOIP-UBA PF16678.5 ORY98018.1 - 0.046 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_4 PF18036.1 ORY98018.1 - 0.13 12.4 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Presenilin PF01080.17 ORY98018.1 - 0.17 10.6 4.5 0.31 9.8 0.1 2.2 2 0 0 2 2 2 0 Presenilin Dicty_REP PF05086.12 ORY98018.1 - 0.23 9.4 4.0 0.36 8.8 4.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 ORY98018.1 - 0.7 9.9 29.5 0.031 14.3 22.9 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein GerD PF17898.1 ORY98018.1 - 2.8 7.9 8.8 2.1 8.3 0.8 2.5 1 1 1 2 2 2 0 Spore germination GerD central core domain DUF3439 PF11921.8 ORY98018.1 - 5.5 7.0 12.6 12 5.9 12.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MCLC PF05934.11 ORY98018.1 - 6.7 5.3 9.3 10 4.7 9.3 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Cupin_8 PF13621.6 ORY98020.1 - 4.7e-23 82.2 1.7 8e-23 81.4 1.7 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY98020.1 - 1.4e-15 57.7 0.5 1.4e-15 57.7 0.5 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase SUIM_assoc PF16619.5 ORY98020.1 - 0.094 12.8 3.0 0.11 12.6 0.3 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med15 PF09606.10 ORY98020.1 - 0.28 9.8 4.9 4.7 5.8 0.0 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CoA_binding PF02629.19 ORY98024.1 - 5.9e-29 100.6 2.1 9.6e-29 99.9 0.3 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ORY98024.1 - 5.1e-25 88.1 0.3 9.3e-25 87.2 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ORY98024.1 - 9.6e-09 35.2 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ORY98024.1 - 0.0004 20.8 0.1 0.0015 19.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Pkinase PF00069.25 ORY98025.1 - 5.7e-60 202.9 0.0 7.8e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98025.1 - 3.9e-42 144.3 0.0 6.3e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY98025.1 - 7e-20 71.1 0.4 1e-10 41.8 0.1 2.9 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 ORY98025.1 - 1.9e-05 23.6 0.1 1.9e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY98025.1 - 0.00059 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY98025.1 - 0.0038 17.2 3.1 0.29 11.0 0.7 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY98025.1 - 0.023 14.0 0.5 0.048 13.0 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mt_ATP-synt_B PF05405.14 ORY98025.1 - 0.089 12.4 0.4 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF496 PF04363.12 ORY98025.1 - 0.94 9.5 4.5 2.4 8.2 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF496) CK2S PF15011.6 ORY98026.1 - 1.8e-12 47.5 0.4 3.2e-12 46.6 0.4 1.4 1 0 0 1 1 1 1 Casein Kinase 2 substrate MinE PF03776.14 ORY98026.1 - 0.0015 18.5 0.8 0.43 10.6 0.2 2.4 2 0 0 2 2 2 2 Septum formation topological specificity factor MinE Vwaint PF14624.6 ORY98026.1 - 0.017 15.2 1.0 0.033 14.3 0.6 1.7 1 1 1 2 2 2 0 VWA / Hh protein intein-like FYRC PF05965.14 ORY98027.1 - 7.1e-19 67.8 0.0 1.8e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 ORY98027.1 - 1.7e-18 66.2 0.4 3.4e-18 65.2 0.4 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus CdvA PF18822.1 ORY98027.1 - 0.007 16.2 0.9 0.077 12.8 1.3 2.0 2 0 0 2 2 2 1 CdvA-like coiled-coil domain SOGA PF11365.8 ORY98027.1 - 0.14 13.3 0.5 0.14 13.3 0.5 2.0 2 0 0 2 2 2 0 Protein SOGA Tsc35 PF15079.6 ORY98027.1 - 2.9 7.4 5.6 5.2 6.6 5.6 1.4 1 0 0 1 1 1 0 Testis-specific protein 35 HLH PF00010.26 ORY98028.1 - 1.1e-14 54.1 1.3 2.5e-14 53.0 1.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_3_C PF01915.22 ORY98029.1 - 6.7e-62 209.1 0.0 1.1e-61 208.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY98029.1 - 1.2e-44 153.1 0.0 1.8e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY98029.1 - 9e-25 86.6 0.1 1.8e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DPBB_1 PF03330.18 ORY98030.1 - 4e-07 30.2 0.0 6.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY98030.1 - 0.04 13.8 0.5 0.063 13.1 0.1 1.5 2 0 0 2 2 2 0 Barwin family Acyltransferase PF01553.21 ORY98031.1 - 1.6e-06 27.8 0.0 7.9e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Histone PF00125.24 ORY98032.1 - 7.6e-52 175.1 2.8 8.4e-52 175.0 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY98032.1 - 1.4e-05 25.4 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY98032.1 - 7.4e-05 22.8 0.4 0.00013 22.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY98032.1 - 0.00015 22.3 1.6 0.00019 22.0 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY98032.1 - 0.0015 18.8 0.1 0.0028 17.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY98032.1 - 0.016 15.3 0.2 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY98032.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Actin PF00022.19 ORY98033.1 - 1.9e-83 280.3 0.0 2.9e-82 276.5 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY98033.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Aldo_ket_red PF00248.21 ORY98034.1 - 1.1e-57 195.5 0.0 6.9e-56 189.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3459 PF11941.8 ORY98035.1 - 0.031 14.6 0.1 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) PPR_2 PF13041.6 ORY98036.1 - 1.2e-12 47.8 0.0 2.4e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 ORY98036.1 - 6.2e-05 23.0 0.0 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 ORY98036.1 - 0.00012 22.0 0.1 0.0029 17.8 0.0 3.0 3 0 0 3 3 3 1 PPR repeat DUF4003 PF13170.6 ORY98036.1 - 0.02 14.3 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) PPR_1 PF12854.7 ORY98036.1 - 0.041 13.6 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 PPR repeat TPR_14 PF13428.6 ORY98036.1 - 0.065 14.1 0.0 11 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.12 ORY98037.1 - 5.5e-36 123.8 0.1 8.4e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Adap_comp_sub PF00928.21 ORY98039.1 - 1.4e-86 290.1 0.0 1.8e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY98039.1 - 1.6e-05 24.9 1.2 2.8e-05 24.1 1.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 ORY98039.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF3176 PF11374.8 ORY98040.1 - 1.8e-12 47.4 0.0 3.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Transport_MerF PF11431.8 ORY98040.1 - 0.07 13.0 1.1 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Membrane transport protein MerF Yip1 PF04893.17 ORY98041.1 - 1.8e-10 40.8 14.0 2.9e-10 40.1 14.0 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2374 PF09574.10 ORY98041.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (Duf2374) AAA_21 PF13304.6 ORY98042.1 - 2.6 7.7 10.9 3.7 7.3 10.9 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ubiquitin PF00240.23 ORY98043.1 - 8.3e-06 25.5 0.2 1.6e-05 24.5 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY98043.1 - 0.00079 19.8 0.1 0.0053 17.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain UN_NPL4 PF11543.8 ORY98043.1 - 0.083 13.4 0.0 0.097 13.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 CPDase PF07823.11 ORY98043.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein IFRD PF05004.13 ORY98044.1 - 3.9e-52 177.3 3.1 7.7e-52 176.3 3.1 1.5 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 ORY98044.1 - 0.15 12.6 1.7 2.9 8.5 0.1 3.3 3 1 1 4 4 4 0 HEAT-like repeat Prefoldin PF02996.17 ORY98045.1 - 6.3e-30 103.6 3.2 8.1e-30 103.2 3.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit UPF0449 PF15136.6 ORY98045.1 - 0.032 14.7 4.6 2.6 8.6 4.6 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 End3 PF12761.7 ORY98045.1 - 0.18 12.0 3.3 0.15 12.3 0.5 2.0 1 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.11 ORY98045.1 - 0.7 10.5 4.6 4.4 7.9 4.6 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Lipase_GDSL PF00657.22 ORY98046.1 - 2.9e-11 43.7 0.1 8.6e-11 42.2 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY98046.1 - 6e-07 30.0 0.0 1.3e-06 28.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Vfa1 PF08432.10 ORY98048.1 - 1e-32 113.9 6.0 1.3e-32 113.6 6.0 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.16 ORY98048.1 - 0.0031 16.9 0.7 0.0042 16.5 0.7 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 FAM176 PF14851.6 ORY98048.1 - 0.099 12.3 3.7 0.14 11.8 3.7 1.3 1 0 0 1 1 1 0 FAM176 family VSG_B PF13206.6 ORY98048.1 - 0.12 11.6 4.9 0.16 11.2 4.9 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain CobT PF06213.12 ORY98048.1 - 0.3 10.4 6.9 0.36 10.2 6.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 ORY98048.1 - 0.31 9.8 6.0 0.38 9.5 6.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 ORY98048.1 - 0.37 8.7 0.3 0.46 8.3 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_phi PF04931.13 ORY98048.1 - 0.95 7.5 7.1 1.2 7.1 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 ORY98048.1 - 2.5 7.0 4.6 3.2 6.6 4.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 ORY98048.1 - 4.6 5.4 9.6 5.3 5.2 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 ORY98048.1 - 9.8 4.8 6.7 11 4.6 6.7 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_L24e PF01246.20 ORY98049.1 - 9.7e-32 109.0 0.2 1.9e-31 108.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Recombinase PF07508.13 ORY98049.1 - 0.015 15.7 0.5 0.017 15.5 0.5 1.3 1 0 0 1 1 1 0 Recombinase DUF1295 PF06966.12 ORY98050.1 - 2.4e-42 145.1 14.6 5.2e-42 144.0 14.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY98050.1 - 0.0058 17.0 2.3 0.019 15.4 0.1 2.8 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Kinesin PF00225.23 ORY98051.1 - 1.6e-102 342.9 3.3 3e-102 342.0 3.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY98051.1 - 2e-23 83.0 0.2 7.9e-23 81.0 0.2 2.0 2 0 0 2 2 2 1 Microtubule binding Seryl_tRNA_N PF02403.22 ORY98051.1 - 0.0049 17.1 2.3 0.0049 17.1 2.3 2.4 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain PKcGMP_CC PF16808.5 ORY98051.1 - 0.11 12.4 0.3 3.1 7.7 0.0 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IFP_35_N PF07334.13 ORY98051.1 - 0.3 11.2 2.1 1.9 8.6 0.3 2.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4407 PF14362.6 ORY98051.1 - 0.73 9.1 7.3 2.1 7.6 7.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CC2-LZ PF16516.5 ORY98051.1 - 1.1 9.6 10.9 0.65 10.4 3.2 2.5 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAM184 PF15665.5 ORY98051.1 - 3.3 7.4 14.8 1.5 8.6 6.9 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B UPF0242 PF06785.11 ORY98051.1 - 4 7.5 11.8 11 6.1 3.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 ORY98051.1 - 4.1 7.8 13.4 3.2 8.1 2.4 2.5 2 0 0 2 2 2 0 Fez1 CSN5_C PF18323.1 ORY98051.1 - 6.7 7.7 6.9 2.3e+02 2.8 6.9 3.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Wbp11 PF09429.10 ORY98052.1 - 1.1e-19 70.6 17.6 1.1e-19 70.6 17.6 3.2 2 1 0 2 2 2 1 WW domain binding protein 11 PEX11 PF05648.14 ORY98053.1 - 2e-46 158.3 0.1 2.3e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ish1 PF10281.9 ORY98054.1 - 2.5e-05 24.5 1.1 2.5e-05 24.5 1.1 2.0 2 0 0 2 2 1 1 Putative stress-responsive nuclear envelope protein Apolipoprotein PF01442.18 ORY98054.1 - 0.0013 18.6 24.6 0.2 11.5 6.4 3.6 2 2 1 3 3 3 3 Apolipoprotein A1/A4/E domain UBA_6 PF18039.1 ORY98054.1 - 0.01 15.7 0.9 0.096 12.6 0.0 3.1 3 1 0 3 3 3 0 UBA-like domain ENT PF03735.14 ORY98054.1 - 0.025 14.6 4.2 0.046 13.8 0.4 3.0 3 0 0 3 3 3 0 ENT domain DUF1451 PF07295.11 ORY98054.1 - 0.11 12.5 0.2 0.11 12.5 0.2 5.0 4 2 1 5 5 5 0 Zinc-ribbon containing domain EnY2 PF10163.9 ORY98054.1 - 0.23 11.9 4.2 1.1 9.7 0.0 3.7 3 1 1 4 4 4 0 Transcription factor e(y)2 Spore_III_AB PF09548.10 ORY98054.1 - 0.43 10.7 5.0 0.56 10.3 0.7 2.8 2 2 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF1002 PF06207.11 ORY98054.1 - 0.62 9.6 14.5 10 5.5 2.0 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF1002) Baculo_PEP_C PF04513.12 ORY98054.1 - 2.4 8.2 13.0 9.8 6.2 0.7 4.1 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 ORY98054.1 - 6 7.5 22.5 17 6.1 0.3 5.5 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 ORY98054.1 - 8.5 7.0 11.8 56 4.4 0.6 5.2 4 2 0 4 4 4 0 YtxH-like protein FA_desaturase PF00487.24 ORY98055.1 - 3.6e-14 53.2 27.9 5.9e-14 52.5 27.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY98055.1 - 1.4e-12 47.6 0.0 3.9e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pex19 PF04614.12 ORY98056.1 - 2.9e-64 217.2 29.0 2.9e-64 217.2 29.0 1.9 1 1 1 2 2 2 1 Pex19 protein family TraC PF07820.12 ORY98056.1 - 0.13 12.6 1.1 0.54 10.6 0.2 2.4 1 1 1 2 2 2 0 TraC-like protein ASD2 PF08687.11 ORY98056.1 - 0.28 10.7 11.9 0.27 10.7 10.9 1.5 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 Peroxin-13_N PF04088.13 ORY98056.1 - 0.31 11.3 1.2 0.58 10.4 0.3 1.9 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF445 PF04286.12 ORY98056.1 - 0.34 10.7 6.0 0.66 9.7 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) CAP_N PF01213.19 ORY98056.1 - 0.82 9.1 9.8 1.5 8.3 9.4 1.7 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Spore_III_AB PF09548.10 ORY98056.1 - 1.5 8.9 9.3 1.5 8.9 4.3 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF935 PF06074.12 ORY98056.1 - 2.1 7.0 13.5 0.82 8.3 9.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF935) CNDH2_C PF16858.5 ORY98056.1 - 3.3 7.5 19.0 0.8 9.5 14.9 1.9 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SesA PF17107.5 ORY98056.1 - 3.5 7.8 6.5 1.5 9.0 1.8 2.8 2 2 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TMPIT PF07851.13 ORY98056.1 - 8.7 5.5 7.9 14 4.8 7.7 1.4 1 1 0 1 1 1 0 TMPIT-like protein TerB_C PF15615.6 ORY98056.1 - 9.9 6.4 13.5 1.8 8.8 5.8 2.7 1 1 1 2 2 2 0 TerB-C domain TPR_14 PF13428.6 ORY98057.1 - 0.0001 22.8 3.5 0.58 11.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98057.1 - 0.0005 20.7 0.1 0.46 11.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY98057.1 - 0.012 15.9 4.1 12 6.5 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY98057.1 - 0.081 13.2 3.5 5.1 7.5 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY98057.1 - 0.099 12.8 12.0 4.9 7.5 0.6 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY98057.1 - 0.25 11.5 1.4 12 6.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY98057.1 - 0.25 11.0 8.4 0.58 9.9 0.0 4.3 6 0 0 6 6 6 0 TPR repeat TPR_19 PF14559.6 ORY98057.1 - 0.8 10.3 8.9 21 5.7 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Aldedh PF00171.22 ORY98058.1 - 0.038 12.5 0.3 0.049 12.1 0.3 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ribosomal_S20p PF01649.18 ORY98058.1 - 0.062 13.9 0.2 0.12 13.0 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 XPG_N PF00752.17 ORY98061.1 - 9.5e-24 83.8 0.0 2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORY98061.1 - 7.3e-23 80.7 0.0 1.9e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 ORY98061.1 - 1.6e-07 31.8 0.0 4.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 ORY98061.1 - 0.00023 20.8 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 ORY98061.1 - 0.031 14.4 0.2 0.085 13.0 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HHH_5 PF14520.6 ORY98061.1 - 0.075 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2673 PF10880.8 ORY98061.1 - 0.13 12.4 0.2 0.23 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) TPR_1 PF00515.28 ORY98061.1 - 0.14 12.0 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat 5_nucleotid PF05761.14 ORY98062.1 - 1.2e-117 393.6 0.0 1.4e-117 393.4 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family DAHP_synth_2 PF01474.16 ORY98063.1 - 3.7e-204 678.2 0.0 4.2e-204 678.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family CX9C PF16860.5 ORY98065.1 - 2e-06 27.7 3.6 0.015 15.3 0.6 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 ORY98065.1 - 4.1e-05 23.8 4.2 0.00031 20.9 4.4 1.9 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 ORY98065.1 - 0.00048 20.2 5.8 0.0022 18.1 5.8 1.9 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 ORY98065.1 - 0.0061 16.5 3.7 0.032 14.3 1.1 2.0 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 ORY98065.1 - 0.0069 16.1 2.1 0.041 13.6 0.3 2.0 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.16 ORY98065.1 - 0.011 15.9 1.2 0.014 15.6 1.2 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 ORY98065.1 - 0.017 15.4 1.2 0.4 11.1 2.3 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 ORY98065.1 - 0.04 14.3 2.9 0.12 12.8 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DEAD PF00270.29 ORY98066.1 - 1.6e-45 155.0 0.2 3e-45 154.1 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 ORY98066.1 - 2.9e-23 81.9 0.0 1.2e-22 79.8 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 ORY98066.1 - 3.4e-23 82.1 0.0 8.5e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY98066.1 - 3.3e-08 33.7 1.1 9.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 ORY98066.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) UvrD-helicase PF00580.21 ORY98066.1 - 0.086 12.4 0.0 0.086 12.4 0.0 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 ORY98066.1 - 0.73 10.1 3.5 3.8 7.8 1.4 3.3 2 1 0 2 2 2 0 AAA domain Borrelia_P83 PF05262.11 ORY98066.1 - 0.75 8.2 16.4 1 7.8 16.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TCO89 PF10452.9 ORY98067.1 - 0.00018 20.7 0.5 0.00018 20.7 0.5 2.9 1 1 1 2 2 2 1 TORC1 subunit TCO89 Aldedh PF00171.22 ORY98068.1 - 3.3e-85 286.3 0.0 3.9e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arginase PF00491.21 ORY98069.1 - 1.9e-78 263.8 0.0 2.2e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family Glucosamine_iso PF01182.20 ORY98070.1 - 1.4e-78 263.9 0.0 1.6e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L34e PF01199.18 ORY98071.1 - 1.1e-43 147.4 6.1 1.5e-43 147.0 6.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e ER PF01133.17 ORY98072.1 - 1.5e-31 108.3 0.0 1.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Enhancer of rudimentary PH PF00169.29 ORY98073.1 - 1.8e-08 34.9 0.1 5.8e-08 33.2 0.1 2.0 1 0 0 1 1 1 1 PH domain IFT57 PF10498.9 ORY98073.1 - 0.00054 19.0 7.8 0.00054 19.0 7.8 4.6 4 1 0 4 4 4 1 Intra-flagellar transport protein 57 GIT_CC PF16559.5 ORY98073.1 - 0.019 14.8 0.5 0.019 14.8 0.5 4.3 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 ORY98073.1 - 0.065 13.3 0.4 0.065 13.3 0.4 5.9 6 2 2 8 8 8 0 bZIP transcription factor LapA_dom PF06305.11 ORY98074.1 - 2.6 7.9 7.5 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_L3 PF00297.22 ORY98075.1 - 1.6e-177 590.0 9.8 1.9e-177 589.8 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Tho1_MOS11_C PF18592.1 ORY98075.1 - 0.075 12.8 0.5 0.42 10.5 0.0 2.4 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain SRP14 PF02290.15 ORY98076.1 - 6.6e-19 68.1 0.6 1e-18 67.4 0.6 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Mito_carr PF00153.27 ORY98077.1 - 4.5e-45 151.5 1.5 5.1e-19 68.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tropomyosin_1 PF12718.7 ORY98078.1 - 1.2e-21 77.3 33.5 1.3e-11 44.8 16.0 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 ORY98078.1 - 1.2e-08 34.7 29.5 1.3e-08 34.5 29.5 1.0 1 0 0 1 1 1 1 Tropomyosin GAS PF13851.6 ORY98078.1 - 0.0017 17.7 20.5 0.0017 17.7 20.5 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 ORY98078.1 - 0.0034 17.0 18.7 0.0077 15.8 18.7 1.6 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain Uso1_p115_C PF04871.13 ORY98078.1 - 0.0047 17.3 30.0 0.015 15.7 17.4 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Cast PF10174.9 ORY98078.1 - 0.0056 15.0 16.5 0.0066 14.7 16.5 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF4201 PF13870.6 ORY98078.1 - 0.0065 16.2 20.8 0.0068 16.2 16.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) ATG16 PF08614.11 ORY98078.1 - 0.007 16.6 25.4 0.038 14.2 25.4 1.8 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 ORY98078.1 - 0.014 15.4 2.7 0.014 15.4 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Caskin-tail PF16632.5 ORY98078.1 - 0.023 15.1 0.6 0.023 15.1 0.6 2.7 2 1 1 3 3 2 0 C-terminal region of Caskin DUF3450 PF11932.8 ORY98078.1 - 0.024 14.0 19.1 0.23 10.7 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 ORY98078.1 - 0.028 15.0 19.6 0.13 12.8 9.9 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Fez1 PF06818.15 ORY98078.1 - 0.031 14.7 20.1 0.017 15.6 17.3 1.6 1 1 0 1 1 1 0 Fez1 Seryl_tRNA_N PF02403.22 ORY98078.1 - 0.041 14.1 22.8 0.085 13.1 10.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 ORY98078.1 - 0.043 13.9 28.4 0.065 13.3 11.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 ORY98078.1 - 0.048 11.8 20.2 0.053 11.7 20.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 ORY98078.1 - 0.054 12.4 24.1 0.076 11.9 24.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein MCC-bdg_PDZ PF10506.9 ORY98078.1 - 0.057 13.4 2.3 0.057 13.4 2.3 2.4 1 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HOOK PF05622.12 ORY98078.1 - 0.061 11.5 20.3 0.073 11.2 20.3 1.2 1 0 0 1 1 1 0 HOOK protein DUF2968 PF11180.8 ORY98078.1 - 0.061 13.0 15.1 0.38 10.4 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) FlaC_arch PF05377.11 ORY98078.1 - 0.079 13.4 14.3 1.6 9.2 0.2 3.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 ORY98078.1 - 0.091 13.0 9.5 3.2 8.1 0.1 3.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF4407 PF14362.6 ORY98078.1 - 0.1 12.0 14.4 0.13 11.6 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_MT_bd PF06657.13 ORY98078.1 - 0.1 13.1 17.9 0.2 12.2 9.7 2.9 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Nsp1_C PF05064.13 ORY98078.1 - 0.11 12.3 16.7 0.21 11.4 5.2 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Laminin_II PF06009.12 ORY98078.1 - 0.11 12.5 14.4 0.3 11.1 5.5 2.1 1 1 1 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 ORY98078.1 - 0.12 12.4 27.4 0.41 10.7 10.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 ORY98078.1 - 0.13 13.0 21.0 0.25 12.1 11.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Nup54 PF13874.6 ORY98078.1 - 0.13 12.4 16.1 0.11 12.6 10.9 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 PspA_IM30 PF04012.12 ORY98078.1 - 0.13 11.8 24.2 1.2 8.6 13.3 2.2 1 1 1 2 2 2 0 PspA/IM30 family SHE3 PF17078.5 ORY98078.1 - 0.16 11.7 19.5 0.35 10.6 19.5 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 ORY98078.1 - 0.21 11.0 20.3 0.25 10.8 20.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF724 PF05266.14 ORY98078.1 - 0.22 11.3 20.7 0.048 13.5 11.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Alanine_zipper PF11839.8 ORY98078.1 - 0.23 11.9 18.5 0.065 13.6 2.2 2.6 1 1 2 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein DUF812 PF05667.11 ORY98078.1 - 0.23 10.3 21.7 0.42 9.4 21.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Mod_r PF07200.13 ORY98078.1 - 0.23 11.5 21.9 5.3 7.1 21.9 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Occludin_ELL PF07303.13 ORY98078.1 - 0.26 12.0 13.1 4.9 7.9 3.2 2.9 1 1 2 3 3 3 0 Occludin homology domain Lebercilin PF15619.6 ORY98078.1 - 0.28 10.8 25.6 0.15 11.7 22.5 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Allexi_40kDa PF05549.11 ORY98078.1 - 0.3 10.6 8.4 0.35 10.3 7.0 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein Lectin_N PF03954.14 ORY98078.1 - 0.3 10.8 10.5 1.6 8.5 3.3 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4200 PF13863.6 ORY98078.1 - 0.35 11.3 27.2 0.79 10.1 24.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 ORY98078.1 - 0.37 10.8 27.8 2 8.5 10.4 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 ORY98078.1 - 0.56 10.4 24.4 1.4 9.2 24.3 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ABC_tran_CTD PF16326.5 ORY98078.1 - 0.56 10.5 31.2 7.2 6.9 21.6 3.1 1 1 2 3 3 3 0 ABC transporter C-terminal domain Med4 PF10018.9 ORY98078.1 - 0.57 9.8 17.2 0.67 9.6 7.6 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 APG6_N PF17675.1 ORY98078.1 - 0.63 10.6 35.4 1.3 9.5 15.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region SpecificRecomb PF10136.9 ORY98078.1 - 0.63 8.3 6.2 0.68 8.2 6.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase Sec34 PF04136.15 ORY98078.1 - 0.64 9.9 12.3 1.4 8.8 0.6 2.7 1 1 1 2 2 2 0 Sec34-like family HAUS-augmin3 PF14932.6 ORY98078.1 - 0.68 9.5 22.1 11 5.5 22.1 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3552 PF12072.8 ORY98078.1 - 0.72 9.2 23.6 0.98 8.8 23.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF745 PF05335.13 ORY98078.1 - 0.75 9.5 16.9 0.087 12.5 9.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Prefoldin_2 PF01920.20 ORY98078.1 - 0.8 9.7 25.6 1.6 8.7 7.4 3.2 1 1 2 3 3 3 0 Prefoldin subunit Exonuc_VII_L PF02601.15 ORY98078.1 - 0.92 9.0 12.2 0.95 9.0 12.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.6 ORY98078.1 - 1 7.9 19.6 1.8 7.1 19.6 1.4 1 1 0 1 1 1 0 AAA domain DUF1943 PF09172.11 ORY98078.1 - 1.1 8.5 5.9 1.3 8.2 5.8 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) FPP PF05911.11 ORY98078.1 - 1.1 7.3 23.5 3.8 5.6 23.5 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil BRE1 PF08647.11 ORY98078.1 - 1.2 9.2 23.4 0.3 11.2 18.2 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMPIT PF07851.13 ORY98078.1 - 1.2 8.3 13.3 2 7.6 13.3 1.5 1 1 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.17 ORY98078.1 - 1.2 9.0 20.3 1.3 8.9 1.4 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF948 PF06103.11 ORY98078.1 - 1.3 9.3 7.7 6 7.2 1.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 ORY98078.1 - 1.4 9.5 13.0 1.6 9.3 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 CENP-H PF05837.12 ORY98078.1 - 1.4 9.3 23.3 0.95 9.9 8.2 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2730 PF10805.8 ORY98078.1 - 1.5 8.9 11.2 6.4 6.9 7.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.10 ORY98078.1 - 1.6 8.9 10.7 3.9 7.6 5.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 ORY98078.1 - 1.6 9.5 14.4 1.9 9.2 4.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TFA2_Winged_2 PF18121.1 ORY98078.1 - 1.7 8.4 5.6 1.5 8.6 0.4 2.9 2 1 1 3 3 3 0 TFA2 Winged helix domain 2 ERM PF00769.19 ORY98078.1 - 1.8 8.3 31.2 4.6 7.0 31.2 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FUSC PF04632.12 ORY98078.1 - 1.9 6.9 7.0 2 6.8 7.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2514 PF10721.9 ORY98078.1 - 2 8.4 11.8 0.26 11.3 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) XhlA PF10779.9 ORY98078.1 - 2.4 8.4 21.0 0.43 10.8 1.4 3.2 1 1 3 4 4 4 0 Haemolysin XhlA UPF0242 PF06785.11 ORY98078.1 - 2.5 8.2 23.6 4.2 7.4 23.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 ORY98078.1 - 2.7 8.1 11.4 5 7.3 1.4 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation Bacillus_HBL PF05791.11 ORY98078.1 - 2.8 7.7 11.1 1.8 8.4 2.3 2.6 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) HIP1_clath_bdg PF16515.5 ORY98078.1 - 2.9 8.6 21.8 1.4 9.5 8.2 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HemX PF04375.14 ORY98078.1 - 3 7.0 16.9 1.3 8.3 6.1 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3584 PF12128.8 ORY98078.1 - 3.2 5.2 21.3 3.5 5.0 21.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GrpE PF01025.19 ORY98078.1 - 3.7 7.2 27.0 1.4 8.6 8.6 2.8 1 1 2 3 3 3 0 GrpE ADIP PF11559.8 ORY98078.1 - 6 6.9 22.0 1.9 8.6 7.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_I PF06008.14 ORY98078.1 - 6.1 6.5 24.4 9.7 5.8 24.4 1.4 1 1 0 1 1 1 0 Laminin Domain I Tox-ODYAM1 PF15642.6 ORY98078.1 - 6.5 5.6 12.3 7.5 5.4 12.3 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Atg14 PF10186.9 ORY98078.1 - 6.6 5.7 17.4 30 3.6 17.4 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 5_nucleotid PF05761.14 ORY98078.1 - 6.9 5.5 9.8 8.2 5.2 9.8 1.3 1 0 0 1 1 1 0 5' nucleotidase family FAM76 PF16046.5 ORY98078.1 - 7.2 5.9 14.3 9.9 5.4 12.8 1.7 1 1 1 2 2 2 0 FAM76 protein LMBR1 PF04791.16 ORY98078.1 - 7.7 5.3 12.2 8.9 5.1 12.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Vir_act_alpha_C PF10400.9 ORY98078.1 - 7.7 7.3 16.0 1.6 9.5 3.7 3.0 1 1 1 2 2 2 0 Virulence activator alpha C-term Spc24 PF08286.11 ORY98078.1 - 9.8 6.5 23.9 6.1 7.1 3.4 3.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cg6151-P PF10233.9 ORY98079.1 - 1.8e-28 99.1 13.2 2.1e-28 98.9 13.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 ORY98079.1 - 0.19 11.4 5.8 0.24 11.1 5.8 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 PRA1 PF03208.19 ORY98079.1 - 2.4 7.8 14.5 9.8 5.8 14.4 1.8 1 1 0 1 1 1 0 PRA1 family protein Peptidase_U4 PF03419.13 ORY98079.1 - 9 5.5 10.3 11 5.2 10.3 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2052 PF09747.9 ORY98082.1 - 3.2e-43 148.2 20.0 5.4e-43 147.4 20.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Sporozoite_P67 PF05642.11 ORY98082.1 - 3.2 5.7 5.7 4.4 5.3 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HSF_DNA-bind PF00447.17 ORY98083.1 - 1.6e-32 112.0 2.3 1.6e-32 112.0 2.3 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Folliculin PF11704.8 ORY98083.1 - 0.011 15.7 5.2 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1266 PF06889.11 ORY98083.1 - 0.086 12.9 3.3 0.076 13.1 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) ALMS_motif PF15309.6 ORY98083.1 - 2.7 8.5 14.1 0.92 10.0 1.2 2.4 2 0 0 2 2 2 0 ALMS motif ADH_zinc_N PF00107.26 ORY98084.1 - 5.5e-33 113.7 0.3 8.1e-33 113.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY98084.1 - 6.4e-15 56.4 0.0 1.1e-14 55.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY98084.1 - 5.5e-07 29.4 0.0 1.5e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ORY98084.1 - 0.005 16.2 1.2 0.0075 15.6 1.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Rit1_C PF17184.4 ORY98085.1 - 2.4e-99 332.2 0.1 3e-99 331.9 0.1 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 ORY98085.1 - 5.7e-26 91.0 0.0 2.1e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain DSPc PF00782.20 ORY98085.1 - 5e-09 36.1 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 ORY98085.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_10 PF05971.12 ORY98086.1 - 7.5e-76 255.3 0.0 9.2e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 ORY98086.1 - 6.5e-09 35.6 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY98086.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 ORY98086.1 - 0.0089 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 ORY98086.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein N6_Mtase PF02384.16 ORY98086.1 - 0.029 13.7 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase TPR_19 PF14559.6 ORY98087.1 - 5e-14 52.6 0.6 9.1e-07 29.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY98087.1 - 6.8e-11 42.1 0.6 0.42 11.6 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY98087.1 - 3.9e-09 35.9 0.0 0.11 12.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 ORY98087.1 - 3.5e-08 33.3 0.5 0.17 12.6 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98087.1 - 7.2e-08 32.9 0.0 0.00013 22.6 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY98087.1 - 7.8e-08 32.5 2.5 0.0012 19.1 0.1 3.5 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY98087.1 - 1.9e-07 31.0 1.2 0.0074 16.6 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY98087.1 - 2.1e-06 28.0 0.2 0.79 10.5 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY98087.1 - 2.9e-06 26.9 0.1 0.79 9.6 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY98087.1 - 1.4e-05 24.8 0.2 0.035 14.1 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY98087.1 - 2.6e-05 23.8 0.2 0.057 13.1 0.0 3.7 4 0 0 4 4 4 1 TPR repeat ANAPC3 PF12895.7 ORY98087.1 - 0.00011 22.4 0.2 0.13 12.5 0.1 2.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 ORY98087.1 - 0.00018 21.3 2.9 0.019 14.7 0.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 ORY98087.1 - 0.0002 21.4 1.7 5.1 7.3 0.0 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 ORY98087.1 - 0.00043 20.0 0.2 1 9.1 0.0 3.1 1 1 2 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.6 ORY98087.1 - 0.00047 20.2 0.9 0.37 11.1 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF1039 PF06287.11 ORY98087.1 - 0.00047 20.5 0.3 0.03 14.7 0.0 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF1039) TPR_15 PF13429.6 ORY98087.1 - 0.0014 17.9 0.3 0.0022 17.3 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY98087.1 - 0.0035 17.2 0.6 3.5 7.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Type_III_YscG PF09477.10 ORY98087.1 - 0.0039 17.3 0.3 0.29 11.2 0.1 2.7 2 1 1 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_20 PF14561.6 ORY98087.1 - 0.018 15.3 0.6 1.1 9.6 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 ORY98087.1 - 0.041 14.1 0.6 1.4 9.1 0.1 2.4 1 1 1 2 2 2 0 HemY protein N-terminus PPR PF01535.20 ORY98087.1 - 0.059 13.6 0.0 6.9 7.2 0.0 2.7 2 0 0 2 2 2 0 PPR repeat SNAP PF14938.6 ORY98087.1 - 0.062 12.7 0.4 0.1 12.0 0.4 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PIP5K PF01504.18 ORY98089.1 - 3.5e-44 151.1 0.4 1.2e-35 123.1 0.9 2.9 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 ORY98089.1 - 2.7e-30 105.4 0.0 4.7e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 ORY98089.1 - 4.2e-17 62.0 11.4 4.2e-17 62.0 11.4 2.4 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 ORY98089.1 - 0.0038 17.4 2.3 0.0038 17.4 2.3 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger Pinin_SDK_N PF04697.13 ORY98089.1 - 0.1 13.2 0.6 0.56 10.8 0.2 2.5 2 0 0 2 2 2 0 pinin/SDK conserved region Abhydrolase_6 PF12697.7 ORY98090.1 - 7.5e-12 46.3 0.0 9.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY98090.1 - 4.6e-06 26.1 0.0 1.1e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY98090.1 - 0.043 13.5 0.0 0.21 11.2 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold bZIP_1 PF00170.21 ORY98091.1 - 1.3e-10 41.2 14.5 3.6e-10 39.8 14.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY98091.1 - 1.7e-05 24.8 20.0 0.00032 20.7 17.3 2.7 1 1 1 2 2 2 1 Basic region leucine zipper Herpes_UL6 PF01763.16 ORY98091.1 - 9.1e-05 21.2 3.1 0.00014 20.6 3.1 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like YabA PF06156.13 ORY98091.1 - 0.0011 19.5 3.3 0.0071 17.0 3.3 2.4 1 0 0 1 1 1 1 Initiation control protein YabA bZIP_Maf PF03131.17 ORY98091.1 - 0.0073 16.8 12.6 0.0073 16.8 12.6 2.5 2 0 0 2 2 2 1 bZIP Maf transcription factor ZapB PF06005.12 ORY98091.1 - 0.019 15.4 9.1 0.019 15.4 9.1 2.7 3 0 0 3 3 3 0 Cell division protein ZapB MRC1 PF09444.10 ORY98091.1 - 0.034 14.7 9.7 0.14 12.6 9.7 2.1 1 0 0 1 1 1 0 MRC1-like domain PKcGMP_CC PF16808.5 ORY98091.1 - 0.038 13.9 3.0 0.13 12.2 3.0 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TSC22 PF01166.18 ORY98091.1 - 0.07 13.4 1.5 0.3 11.4 1.5 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family CREPT PF16566.5 ORY98091.1 - 0.078 13.1 5.4 0.19 11.9 5.4 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour UPF0242 PF06785.11 ORY98091.1 - 0.18 11.9 8.3 0.074 13.2 5.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 ORY98091.1 - 0.24 11.2 5.5 0.46 10.3 4.7 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 Phlebovirus_NSM PF07246.11 ORY98091.1 - 0.49 9.7 11.0 0.15 11.4 8.1 1.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Ribosomal_S20p PF01649.18 ORY98091.1 - 1.5 9.6 5.2 5 7.8 5.2 1.9 1 0 0 1 1 1 0 Ribosomal protein S20 DUF641 PF04859.12 ORY98091.1 - 1.7 8.9 10.6 0.59 10.5 7.2 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 ORY98091.1 - 2.1 6.2 6.8 4.3 5.1 6.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 ORY98091.1 - 6.6 6.8 18.6 0.1 12.7 8.7 2.9 3 1 0 3 3 2 0 Afadin- and alpha -actinin-Binding SbcCD_C PF13558.6 ORY98092.1 - 1.3e-05 25.4 0.1 4.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 ORY98092.1 - 0.3 10.5 8.4 0.58 9.6 8.3 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Prominin PF05478.11 ORY98092.1 - 0.71 7.8 28.3 0.054 11.4 10.6 2.5 2 1 1 3 3 3 0 Prominin DUF2259 PF10016.9 ORY98092.1 - 2 8.3 6.5 0.25 11.3 0.6 2.3 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) DUF4458 PF14660.6 ORY98092.1 - 5.4 7.3 7.2 6.6 7.0 1.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4458) Anp1 PF03452.14 ORY98093.1 - 6.6e-93 310.9 0.1 8.4e-93 310.6 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 ORY98093.1 - 2.3e-07 30.8 0.4 5.7e-06 26.2 0.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 ORY98093.1 - 0.00035 21.0 2.0 0.00091 19.7 2.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 RRM_1 PF00076.22 ORY98094.1 - 1.8e-14 53.3 0.1 3.1e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 ORY98095.1 - 0.0015 18.6 4.5 0.0036 17.3 4.5 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Ribosomal_S14 PF00253.21 ORY98096.1 - 1.2e-24 85.8 0.6 1.9e-24 85.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e HAT PF02184.16 ORY98097.1 - 1.1e-26 92.4 60.7 1.8e-14 53.4 5.0 13.9 16 0 0 16 16 15 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 ORY98097.1 - 1.2e-17 64.2 0.0 4e-05 24.0 0.0 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY98097.1 - 1.7e-17 62.6 12.0 0.00077 20.1 0.0 9.6 4 2 7 11 11 10 5 Tetratricopeptide repeat Suf PF05843.14 ORY98097.1 - 5e-15 56.3 27.4 4.7e-06 26.8 0.6 7.5 2 2 5 7 7 7 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 ORY98097.1 - 7.4e-09 35.4 1.3 0.015 15.6 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY98097.1 - 3.2e-07 29.8 12.6 0.0031 16.8 2.4 4.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY98097.1 - 1.6e-06 27.8 7.3 0.48 10.7 0.1 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98097.1 - 2.7e-06 27.9 0.2 0.00043 20.9 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98097.1 - 0.00028 20.9 1.8 17 6.0 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY98097.1 - 0.00032 20.7 19.3 0.57 10.2 2.1 6.7 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_7 PF13176.6 ORY98097.1 - 0.0026 17.6 0.9 0.56 10.4 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 ORY98097.1 - 0.038 14.1 0.1 18 5.5 0.0 3.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 ORY98097.1 - 0.07 12.8 0.0 0.75 9.5 0.0 2.7 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 ORY98097.1 - 0.12 12.2 3.4 4.5 7.3 0.0 4.7 7 0 0 7 7 7 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 ORY98097.1 - 1.4 9.0 27.3 0.19 11.8 0.5 7.5 6 4 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.6 ORY98097.1 - 2.2 9.1 16.0 42 5.1 0.0 7.9 11 0 0 11 11 9 0 Tetratricopeptide repeat Sugar_tr PF00083.24 ORY98098.1 - 5.2e-89 299.2 18.0 4.1e-47 161.1 4.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY98098.1 - 2.2e-28 99.2 20.9 2.2e-28 99.2 20.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sel1 PF08238.12 ORY98099.1 - 1.8e-41 139.6 26.0 4.7e-08 33.4 0.7 7.9 5 2 2 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 ORY98099.1 - 4.9e-07 30.0 2.9 0.048 14.3 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_5 PF12688.7 ORY98099.1 - 0.023 14.9 0.0 0.29 11.4 0.0 2.3 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_1 PF00515.28 ORY98099.1 - 0.025 14.4 9.3 21 5.1 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY98099.1 - 0.057 13.6 10.0 56 4.2 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98099.1 - 0.81 10.4 0.1 0.81 10.4 0.1 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98099.1 - 0.97 9.8 7.9 60 4.2 0.2 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat Mito_carr PF00153.27 ORY98100.1 - 1.1e-59 198.4 2.7 1.6e-21 76.0 0.0 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY98100.1 - 0.0074 15.5 0.9 0.33 10.1 0.3 2.6 1 1 1 2 2 2 2 Gammaproteobacterial serine protease SAM_LFY PF01698.16 ORY98100.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain BORCS7 PF16088.5 ORY98101.1 - 5.5e-13 49.1 2.0 7.1e-13 48.7 2.0 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 NPA PF16469.5 ORY98101.1 - 0.016 15.8 3.3 0.022 15.3 3.3 1.1 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Aldedh PF00171.22 ORY98102.1 - 4e-131 437.7 0.0 5.2e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tim44 PF04280.15 ORY98103.1 - 2.4e-35 121.8 0.2 2.4e-35 121.8 0.2 2.1 2 1 0 2 2 2 1 Tim44-like domain ISG65-75 PF11727.8 ORY98103.1 - 0.0036 16.6 10.2 0.0036 16.6 10.2 1.7 1 1 1 2 2 2 1 Invariant surface glycoprotein ZapB PF06005.12 ORY98103.1 - 0.018 15.5 5.5 0.018 15.5 5.5 2.2 3 0 0 3 3 3 0 Cell division protein ZapB LMBR1 PF04791.16 ORY98103.1 - 1.3 7.8 6.1 1.8 7.4 6.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein WH1 PF00568.23 ORY98104.1 - 3.6e-24 84.8 0.0 5.5e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 ORY98104.1 - 4e-10 39.9 0.4 6.9e-10 39.1 0.4 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 ORY98104.1 - 0.007 16.2 0.2 0.022 14.6 0.2 1.9 1 0 0 1 1 1 1 WH2 motif FA_FANCE PF11510.8 ORY98105.1 - 0.0026 17.1 3.7 0.0042 16.5 3.7 1.3 1 1 0 1 1 1 1 Fanconi Anaemia group E protein FANCE Trans_reg_C PF00486.28 ORY98105.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Aldo_ket_red PF00248.21 ORY98106.1 - 9.6e-40 136.6 0.0 3.9e-36 124.8 0.0 3.0 1 1 0 1 1 1 1 Aldo/keto reductase family AbiEi_4 PF13338.6 ORY98106.1 - 0.13 12.4 0.0 6 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Glyco_hyd_65N_2 PF14498.6 ORY98107.1 - 0.01 15.7 1.3 0.017 15.0 1.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RPN1_RPN2_N PF17781.1 ORY98108.1 - 2.2e-122 408.3 0.8 4e-122 407.5 0.8 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 ORY98108.1 - 7.6e-31 105.9 0.1 1.4e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 ORY98108.1 - 5.6e-27 92.8 20.1 1.4e-06 28.4 0.1 8.9 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORY98108.1 - 4.7e-06 26.9 0.1 0.17 12.3 0.0 4.4 4 2 1 5 5 5 3 HEAT repeats RPN2_C PF18004.1 ORY98108.1 - 8.6 6.3 9.7 17 5.3 9.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain APG12 PF04110.13 ORY98109.1 - 9.9e-34 115.6 0.0 1.2e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 ORY98109.1 - 0.00014 22.0 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like NIR_SIR PF01077.22 ORY98111.1 - 2.6e-56 189.5 0.0 3.3e-49 166.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 ORY98111.1 - 1.2e-32 113.1 0.1 2.7e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 ORY98111.1 - 9.6e-30 102.2 0.0 6.2e-16 58.0 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 ORY98111.1 - 2.6e-06 27.4 0.3 5.7e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 ORY98111.1 - 4e-05 23.8 2.2 4.9e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II CotH PF08757.11 ORY98112.1 - 3.5e-35 122.1 0.4 4.9e-35 121.6 0.4 1.1 1 0 0 1 1 1 1 CotH kinase protein CotH PF08757.11 ORY98113.1 - 2e-36 126.2 0.3 2.9e-36 125.6 0.3 1.1 1 0 0 1 1 1 1 CotH kinase protein GDA1_CD39 PF01150.17 ORY98114.1 - 6.6e-103 344.6 0.0 7.3e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family BK_channel_a PF03493.18 ORY98116.1 - 1.7e-22 79.4 0.1 5.9e-22 77.7 0.1 2.0 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORY98116.1 - 2.1e-13 50.0 8.9 4.8e-13 48.9 8.9 1.6 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 ORY98116.1 - 1e-05 25.7 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.31 ORY98116.1 - 0.00011 21.6 12.0 0.00024 20.4 12.0 1.5 1 0 0 1 1 1 1 Ion transport protein DUF3346 PF11826.8 ORY98116.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) Ribosomal_S25 PF03297.15 ORY98117.1 - 2.8e-37 126.9 1.2 3.3e-37 126.7 1.2 1.1 1 0 0 1 1 1 1 S25 ribosomal protein BioT2 PF15368.6 ORY98117.1 - 0.0041 17.1 0.1 0.0041 17.1 0.1 1.2 1 0 0 1 1 1 1 Spermatogenesis family BioT2 AIPR PF10592.9 ORY98117.1 - 0.0094 15.6 0.4 0.012 15.2 0.3 1.2 1 1 0 1 1 1 1 AIPR protein HTH_24 PF13412.6 ORY98117.1 - 0.086 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Abhydrolase_3 PF07859.13 ORY98118.1 - 9.5e-57 192.3 0.3 2.5e-56 190.9 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY98118.1 - 1.8e-10 40.3 0.1 3.7e-10 39.3 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 ORY98118.1 - 6e-07 28.6 0.0 7.5e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORY98118.1 - 6.1e-06 25.9 0.1 1.8e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ORY98118.1 - 0.00047 19.1 0.1 0.001 18.1 0.1 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 ORY98118.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Tim54 PF11711.8 ORY98119.1 - 1.8e-57 194.9 0.2 2.1e-57 194.6 0.2 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 CorA PF01544.18 ORY98120.1 - 2.2e-45 155.2 5.2 2.3e-44 151.9 5.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF267 PF03268.14 ORY98120.1 - 0.059 12.2 0.3 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 Pkinase PF00069.25 ORY98122.1 - 4.1e-62 209.9 0.0 4.9e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98122.1 - 1e-41 143.0 0.0 1.3e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98122.1 - 9.1e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY98122.1 - 0.035 13.0 0.1 0.1 11.5 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY98122.1 - 0.04 12.7 0.0 0.08 11.7 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 ORY98123.1 - 3.4e-17 61.0 22.9 0.013 15.5 0.0 11.3 12 0 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 ORY98123.1 - 2.4e-10 40.5 15.8 0.016 15.6 0.1 7.6 5 3 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY98123.1 - 1.5e-07 31.1 18.3 0.03 14.1 0.6 6.8 4 3 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 ORY98123.1 - 0.62 10.8 14.0 1e+02 4.1 0.2 8.6 9 3 0 9 9 9 0 Leucine Rich Repeat Ras PF00071.22 ORY98124.1 - 2.2e-59 199.7 0.4 2.9e-59 199.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY98124.1 - 7.8e-38 129.4 0.1 1.3e-37 128.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY98124.1 - 1.9e-16 60.0 0.1 2.4e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY98124.1 - 6.5e-07 28.9 0.2 9.7e-07 28.4 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORY98124.1 - 9.5e-07 28.5 0.1 6.3e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY98124.1 - 1.8e-06 27.9 0.0 0.0016 18.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 ORY98124.1 - 5.7e-06 25.9 0.1 7.1e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY98124.1 - 8.3e-06 25.9 0.0 1.6e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY98124.1 - 0.00011 21.8 0.1 0.0096 15.5 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 ORY98124.1 - 0.016 14.7 0.1 0.71 9.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein TIR_2 PF13676.6 ORY98124.1 - 0.041 14.5 0.1 0.093 13.3 0.1 1.6 1 1 0 1 1 1 0 TIR domain AAA_7 PF12775.7 ORY98124.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region adh_short PF00106.25 ORY98125.1 - 1.3e-37 129.1 1.4 1.7e-37 128.8 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY98125.1 - 2.5e-31 109.1 1.1 2.9e-31 108.8 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY98125.1 - 4.3e-13 49.6 0.5 5.2e-13 49.3 0.5 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY98125.1 - 1.2e-10 41.6 1.7 1.5e-10 41.2 1.7 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY98125.1 - 1.5e-05 24.6 0.4 2.1e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY98125.1 - 0.00038 19.9 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 ORY98125.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 ORY98125.1 - 0.03 13.9 0.2 0.048 13.2 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family ODR4-like PF14778.6 ORY98125.1 - 0.051 12.5 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like F420_oxidored PF03807.17 ORY98125.1 - 0.052 14.1 0.9 2.6 8.7 0.1 2.9 1 1 2 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Aldo_ket_red PF00248.21 ORY98128.1 - 7.7e-42 143.5 0.0 9.7e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Rtt106 PF08512.12 ORY98129.1 - 1e-26 93.2 0.0 2.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like MscS_TM PF12794.7 ORY98129.1 - 0.8 8.5 0.0 0.8 8.5 0.0 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 BUD22 PF09073.10 ORY98129.1 - 4 6.7 45.3 7.3 5.8 45.3 1.3 1 0 0 1 1 1 0 BUD22 Tma16 PF11176.8 ORY98130.1 - 4.1e-37 127.3 4.1 4.9e-37 127.0 4.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 FAM47 PF14642.6 ORY98130.1 - 0.0015 18.2 1.2 0.002 17.8 1.2 1.1 1 0 0 1 1 1 1 FAM47 family Actin_micro PF17003.5 ORY98130.1 - 0.075 12.2 0.2 0.08 12.1 0.2 1.1 1 0 0 1 1 1 0 Putative actin-like family Mito_fiss_reg PF05308.11 ORY98136.1 - 0.085 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator EF-hand_7 PF13499.6 ORY98137.1 - 3e-11 43.6 2.2 4.5e-11 43.1 2.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY98137.1 - 5.1e-09 35.3 2.4 7.4e-06 25.5 0.8 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY98137.1 - 1.1e-08 34.0 0.6 0.0043 16.5 0.1 3.5 3 1 1 4 4 4 2 EF hand EF-hand_5 PF13202.6 ORY98137.1 - 4.7e-07 29.0 0.3 0.0049 16.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORY98137.1 - 9.4e-07 28.6 2.1 0.0028 17.5 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY98137.1 - 0.1 12.9 0.3 14 6.0 0.1 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PC-Esterase PF13839.6 ORY98138.1 - 1.8e-05 24.6 0.1 6.7e-05 22.8 0.1 2.1 2 1 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL_2 PF13472.6 ORY98138.1 - 0.054 13.9 0.2 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Ebp2 PF05890.12 ORY98139.1 - 1.1e-80 271.1 35.6 1.1e-80 271.1 35.6 1.7 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 TMP-TENI PF02581.17 ORY98139.1 - 0.056 12.8 1.0 0.11 11.9 1.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase MLANA PF14991.6 ORY98140.1 - 0.0017 18.6 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein melan-A Cadherin_C_2 PF16492.5 ORY98140.1 - 0.024 15.4 0.2 0.027 15.2 0.2 1.3 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF2500 PF10694.9 ORY98140.1 - 0.13 12.8 0.1 0.17 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Cytomega_TRL10 PF06084.11 ORY98140.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein WBP-1 PF11669.8 ORY98140.1 - 4 8.1 5.9 16 6.2 5.9 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 CYYR1 PF10873.8 ORY98140.1 - 6.9 7.1 6.2 12 6.4 6.2 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF2701 PF10857.8 ORY98140.1 - 8.5 6.5 7.7 16 5.6 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2701) Ribosomal_L3 PF00297.22 ORY98141.1 - 2.7e-21 76.0 0.8 4.2e-18 65.5 0.8 2.3 1 1 0 1 1 1 1 Ribosomal protein L3 Methyltrn_RNA_2 PF04013.12 ORY98141.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase WD40 PF00400.32 ORY98142.1 - 1e-28 99.0 2.3 1.3e-07 32.2 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY98142.1 - 1.6e-08 34.7 1.2 0.32 11.3 0.2 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY98142.1 - 6.2e-07 28.4 0.3 0.084 11.5 0.0 3.4 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY98142.1 - 0.0044 15.8 0.2 2.8 6.6 0.1 3.1 2 2 1 3 3 3 2 Nup133 N terminal like Ge1_WD40 PF16529.5 ORY98142.1 - 0.021 13.8 0.6 2.8 6.8 0.0 3.1 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cript PF10235.9 ORY98143.1 - 0.85 10.2 4.0 0.35 11.5 1.5 1.7 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT GPI-anchored PF10342.9 ORY98145.1 - 2.5e-13 50.6 4.6 5.9e-13 49.4 4.6 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cytomega_UL20A PF05984.12 ORY98145.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.3 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Apt1 PF10351.9 ORY98145.1 - 2.1 7.1 5.2 2.7 6.7 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FSA_C PF10479.9 ORY98145.1 - 3.4 5.7 13.1 4.1 5.4 13.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ank_4 PF13637.6 ORY98146.1 - 6.6e-18 64.8 0.7 1e-12 48.3 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY98146.1 - 4.3e-16 59.3 1.4 2.8e-09 37.4 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY98146.1 - 1.7e-14 53.7 0.4 7.1e-08 32.6 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY98146.1 - 2.2e-13 49.0 0.4 6.3e-06 26.2 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 ORY98146.1 - 4.5e-12 45.8 1.5 1.4e-05 25.3 0.3 2.8 2 1 1 3 3 3 2 Ankyrin repeat LIM PF00412.22 ORY98147.1 - 1.9e-17 63.2 70.1 5.1e-10 39.4 5.5 6.9 6 2 1 7 7 7 4 LIM domain KH_1 PF00013.29 ORY98148.1 - 7.8e-41 137.7 7.7 3.5e-16 58.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY98148.1 - 1.5e-09 37.6 5.9 0.038 13.8 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY98148.1 - 1.5e-08 34.4 2.1 0.081 12.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY98148.1 - 0.00011 22.2 3.6 0.15 12.1 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain Rhomboid PF01694.22 ORY98149.1 - 1.6e-22 80.1 13.3 1.6e-22 80.1 13.3 1.5 2 0 0 2 2 2 1 Rhomboid family Mersacidin PF16934.5 ORY98149.1 - 6.3 6.6 7.1 11 5.9 0.1 2.7 3 0 0 3 3 3 0 Two-component Enterococcus faecalis cytolysin (EFC) Pkinase PF00069.25 ORY98150.1 - 1.4e-73 247.5 0.1 3.3e-73 246.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98150.1 - 9.5e-36 123.4 0.0 1.7e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98150.1 - 8.6e-05 22.0 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF2252 PF10009.9 ORY98150.1 - 0.0057 15.8 3.3 0.01 15.0 3.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) TFIIA PF03153.13 ORY98150.1 - 0.032 14.3 28.6 0.044 13.8 28.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APH PF01636.23 ORY98150.1 - 0.47 10.3 0.1 0.47 10.3 0.1 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ndc1_Nup PF09531.10 ORY98150.1 - 5.5 5.6 15.4 6.4 5.3 15.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAML PF14963.6 ORY98150.1 - 7.1 6.7 7.6 15 5.6 7.6 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF3801 PF12687.7 ORY98150.1 - 8.5 6.4 18.3 15 5.6 18.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Ribosomal_S3Ae PF01015.18 ORY98151.1 - 9.8e-90 299.5 4.4 1.2e-89 299.3 4.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF4618 PF15397.6 ORY98151.1 - 0.051 13.0 0.7 0.067 12.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TipAS PF07739.13 ORY98151.1 - 0.14 12.7 0.1 1.2 9.7 0.0 2.4 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain ATG22 PF11700.8 ORY98152.1 - 1.2e-95 320.9 20.1 1.6e-95 320.6 20.1 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY98152.1 - 1.9e-10 40.2 27.4 3.6e-07 29.4 3.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF5489 PF17592.2 ORY98152.1 - 0.2 12.2 6.8 6.1 7.4 1.7 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5489) CN_hydrolase PF00795.22 ORY98153.1 - 2.7e-42 144.9 0.0 3.7e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 ORY98153.1 - 1.5e-24 86.5 0.0 3.3e-24 85.4 0.0 1.5 1 1 0 1 1 1 1 NAD synthase AHL_synthase PF17327.2 ORY98153.1 - 0.16 11.0 0.6 0.24 10.4 0.6 1.2 1 0 0 1 1 1 0 Acyl homoserine lactone synthase RRM_1 PF00076.22 ORY98154.1 - 4e-87 286.0 0.5 5.8e-23 80.5 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY98154.1 - 1.2e-28 99.1 2.8 1.4e-27 95.6 2.8 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORY98154.1 - 3e-10 39.7 0.0 0.07 12.7 0.0 4.1 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY98154.1 - 4.3e-06 26.7 3.5 0.04 13.9 1.0 4.5 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 ORY98154.1 - 0.00011 22.1 1.2 3.4 7.8 0.0 4.6 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY98154.1 - 0.00014 21.9 0.1 3.1 8.0 0.0 5.1 3 1 1 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 ORY98154.1 - 0.00055 19.7 0.0 0.022 14.6 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif SET_assoc PF11767.8 ORY98154.1 - 0.00081 19.0 0.0 12 5.7 0.0 3.6 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated OB_RNB PF08206.11 ORY98154.1 - 0.0028 17.3 2.9 1.5 8.5 0.3 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF4523 PF15023.6 ORY98154.1 - 0.021 14.6 0.0 83 2.9 0.0 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF4523) YflT PF11181.8 ORY98154.1 - 0.11 13.0 3.0 5.4 7.6 1.2 2.9 3 0 0 3 3 2 0 Heat induced stress protein YflT DbpA PF03880.15 ORY98154.1 - 0.11 12.5 0.0 19 5.4 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain Vir_act_alpha_C PF10400.9 ORY98154.1 - 0.74 10.5 4.2 23 5.8 0.4 3.1 3 0 0 3 3 3 0 Virulence activator alpha C-term S1 PF00575.23 ORY98155.1 - 1.8e-25 89.0 0.7 1.1e-07 32.1 0.0 5.8 5 1 0 5 5 5 4 S1 RNA binding domain Suf PF05843.14 ORY98155.1 - 4.5e-10 40.0 2.5 1.4e-06 28.6 0.3 5.7 2 1 4 6 6 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY98155.1 - 1.7e-09 37.7 1.2 0.0012 19.4 0.3 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY98155.1 - 6.3e-08 33.0 0.3 0.0025 18.3 0.2 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98155.1 - 3.1e-07 30.9 0.0 0.00025 21.6 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY98155.1 - 9.4e-05 21.7 7.4 9.4e-05 21.7 7.4 3.9 2 1 3 5 5 4 3 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 ORY98155.1 - 0.00084 19.8 5.8 3.6 8.4 0.8 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY98155.1 - 0.001 19.0 7.1 0.034 14.3 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98155.1 - 0.017 15.3 4.3 2.4 8.6 0.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY98155.1 - 0.042 14.1 1.7 0.73 10.1 3.6 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY98155.1 - 0.13 12.6 4.0 3.5 8.0 0.9 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY98155.1 - 0.39 11.2 3.3 16 6.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY98155.1 - 1.7 8.6 7.2 0.086 12.7 0.5 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY98155.1 - 2.9 7.9 6.6 3.3 7.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 ORY98156.1 - 2.1e-26 91.5 0.0 4.4e-15 55.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 ORY98156.1 - 9.2e-23 78.6 0.4 1.2e-06 27.9 0.1 6.0 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 ORY98156.1 - 2.5e-07 30.4 0.0 0.023 14.5 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY98156.1 - 0.00044 19.8 0.0 0.051 13.2 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nrap_D2 PF17403.2 ORY98156.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain RRM_8 PF11835.8 ORY98156.1 - 0.022 15.0 0.0 0.091 13.0 0.0 2.0 2 0 0 2 2 2 0 RRM-like domain nec1 PF10379.9 ORY98156.1 - 0.036 13.6 1.3 3.1 7.3 0.1 2.6 2 0 0 2 2 2 0 Virulence protein nec1 RRM_3 PF08777.11 ORY98156.1 - 0.17 11.9 0.0 7 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Yippee-Mis18 PF03226.14 ORY98157.1 - 1.8e-15 57.1 0.3 2e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORY98157.1 - 0.006 16.8 0.4 0.0089 16.2 0.4 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I S10_plectin PF03501.15 ORY98158.1 - 4e-45 151.8 0.1 4.7e-45 151.6 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 ORY98158.1 - 0.033 14.1 0.1 0.077 12.9 0.1 1.7 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Anoctamin PF04547.12 ORY98159.1 - 3e-110 369.1 16.3 3.5e-110 368.9 16.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel muHD PF10291.9 ORY98160.1 - 7.9e-34 117.3 0.4 7.9e-34 117.3 0.4 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.23 ORY98160.1 - 2.4e-12 47.0 0.4 2.4e-12 47.0 0.4 2.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 ORY98160.1 - 1.1e-05 25.2 0.8 2e-05 24.4 0.8 1.3 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 ORY98160.1 - 0.011 15.4 1.5 0.049 13.3 2.0 1.8 2 0 0 2 2 2 0 BAR domain YfdX PF10938.8 ORY98160.1 - 0.091 12.7 2.0 0.2 11.6 0.9 2.2 2 0 0 2 2 2 0 YfdX protein DUF4404 PF14357.6 ORY98160.1 - 6.4 7.5 7.1 40 4.9 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) HEAT_EZ PF13513.6 ORY98161.1 - 5.3e-26 90.7 10.1 9e-13 48.4 0.1 9.8 9 2 2 11 11 11 3 HEAT-like repeat HEAT PF02985.22 ORY98161.1 - 8e-18 63.0 13.0 0.00039 20.5 0.0 10.0 11 0 0 11 11 10 3 HEAT repeat HEAT_2 PF13646.6 ORY98161.1 - 4.3e-17 62.3 1.9 0.0037 17.6 0.0 6.7 4 3 4 8 8 8 5 HEAT repeats IBN_N PF03810.19 ORY98161.1 - 3e-10 39.9 0.0 7.7e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cnd1 PF12717.7 ORY98161.1 - 8.9e-10 38.8 0.0 0.0064 16.5 0.0 4.8 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY98161.1 - 1.6e-06 28.6 0.0 0.051 14.2 0.0 5.5 4 2 2 6 6 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 ORY98161.1 - 4.7e-06 26.5 0.3 14 5.9 0.0 6.6 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 ORY98161.1 - 0.00079 18.1 0.0 0.3 9.6 0.0 3.5 3 1 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 ORY98161.1 - 0.0028 17.2 0.0 0.43 10.1 0.0 3.7 3 1 1 4 4 4 1 CLASP N terminal Xpo1 PF08389.12 ORY98161.1 - 0.073 13.1 0.0 3.1 7.9 0.0 3.4 3 0 0 3 3 3 0 Exportin 1-like protein DUF3437 PF11919.8 ORY98161.1 - 0.12 12.3 0.1 30 4.6 0.0 4.1 5 0 0 5 5 4 0 Domain of unknown function (DUF3437) RasGEF_N_2 PF14663.6 ORY98161.1 - 0.17 12.3 0.1 3.7 8.0 0.0 3.0 4 0 0 4 4 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pox_Ag35 PF03286.14 ORY98161.1 - 0.98 9.2 3.3 1.6 8.5 3.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MMS19_C PF12460.8 ORY98161.1 - 2.1 7.3 4.6 5.7 5.9 0.1 3.3 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal FYDLN_acid PF09538.10 ORY98161.1 - 4 8.2 12.2 7.6 7.3 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GTP_EFTU PF00009.27 ORY98162.1 - 7e-61 205.2 0.1 1.1e-60 204.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY98162.1 - 4.7e-42 142.6 0.1 1.3e-41 141.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 ORY98162.1 - 1.2e-30 105.4 0.0 2.8e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY98162.1 - 1.4e-26 92.3 0.1 3.6e-26 91.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY98162.1 - 1.1e-11 44.9 0.7 6.1e-11 42.5 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY98162.1 - 1.5e-06 28.1 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ORY98162.1 - 0.0042 17.1 0.0 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ORY98162.1 - 0.047 13.0 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 ORY98162.1 - 0.074 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B PLATZ PF04640.14 ORY98164.1 - 0.00056 20.5 1.9 0.00056 20.5 1.9 2.0 2 0 0 2 2 2 1 PLATZ transcription factor PyrI_C PF02748.15 ORY98164.1 - 0.053 13.4 1.6 7.8 6.5 0.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Opiods_neuropep PF01160.18 ORY98164.1 - 0.066 13.3 2.1 0.066 13.3 2.1 2.4 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide zf-FLZ PF04570.14 ORY98164.1 - 3.3 7.2 10.1 4.5 6.8 6.4 2.5 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 WRKY PF03106.15 ORY98164.1 - 5 7.4 7.1 3 8.1 1.7 2.4 2 1 0 2 2 2 0 WRKY DNA -binding domain Fungal_trans PF04082.18 ORY98166.1 - 1e-26 93.6 0.0 3.1e-26 92.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY98166.1 - 1.1e-09 38.2 10.6 2e-09 37.4 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C14 PF00656.22 ORY98167.1 - 3.4e-64 217.2 0.0 4.3e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ADH_zinc_N PF00107.26 ORY98168.1 - 7.9e-24 84.1 0.3 1.8e-23 83.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY98168.1 - 6e-18 64.7 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY98168.1 - 2.7e-10 41.4 0.0 5.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3993 PF13158.6 ORY98168.1 - 0.04 14.1 0.0 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) ADH_zinc_N PF00107.26 ORY98169.1 - 1.4e-22 80.0 0.2 2.1e-22 79.5 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY98169.1 - 8.5e-19 67.4 0.0 1.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY98169.1 - 1.3e-09 39.2 0.0 2.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY98170.1 - 9.5e-22 77.4 0.1 1.9e-21 76.4 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY98170.1 - 2.5e-19 69.2 0.0 5.1e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY98170.1 - 4.7e-10 40.6 0.0 8.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY98171.1 - 6.7e-22 77.8 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY98171.1 - 2.1e-12 46.9 0.0 3.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY98171.1 - 1.4e-06 29.4 0.0 2.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peripla_BP_3 PF13377.6 ORY98171.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein-like domain DUF1687 PF07955.11 ORY98172.1 - 1.5e-05 25.5 0.0 2.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 ORY98172.1 - 1.6e-05 24.8 0.0 3.7e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 ArsC family FeoB_N PF02421.18 ORY98172.1 - 0.06 12.9 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B InPase PF18823.1 ORY98176.1 - 0.12 12.1 0.6 0.64 9.7 0.1 1.9 2 0 0 2 2 2 0 Inorganic Pyrophosphatase tRNA-synt_2c PF01411.19 ORY98177.1 - 6.3e-212 705.0 0.0 8.7e-212 704.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORY98177.1 - 9.4e-18 64.1 0.3 2.6e-17 62.6 0.2 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ORY98177.1 - 2.4e-16 60.4 6.5 6.5e-16 59.0 6.5 1.8 1 0 0 1 1 1 1 DHHA1 domain DUF4874 PF16173.5 ORY98177.1 - 0.044 13.5 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) MHB PF16525.5 ORY98177.1 - 0.12 12.6 0.2 0.41 10.9 0.2 1.9 1 0 0 1 1 1 0 Haemophore, haem-binding DUF1510 PF07423.11 ORY98180.1 - 0.34 11.1 5.4 2.8 8.1 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) Nup192 PF11894.8 ORY98181.1 - 2.3e-231 771.0 0.0 2.8e-231 770.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 FYRC PF05965.14 ORY98182.1 - 1.3e-18 66.9 0.1 5.8e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 ORY98182.1 - 2.7e-18 65.5 0.9 4.6e-18 64.8 0.9 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus GAS PF13851.6 ORY98182.1 - 0.0038 16.6 0.8 0.0055 16.1 0.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DASH_Dad1 PF08649.10 ORY98182.1 - 0.13 12.5 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad1 Med21 PF11221.8 ORY98182.1 - 0.17 12.1 3.4 2.1 8.6 0.4 3.0 3 0 0 3 3 3 0 Subunit 21 of Mediator complex DUF3673 PF12425.8 ORY98183.1 - 0.057 13.3 0.4 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) KRTDAP PF15200.6 ORY98186.1 - 0.01 15.6 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Keratinocyte differentiation-associated DUF3673 PF12425.8 ORY98186.1 - 0.061 13.2 0.2 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) TFIIA PF03153.13 ORY98188.1 - 0.027 14.5 13.6 0.033 14.2 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY98188.1 - 0.13 11.8 19.5 0.19 11.3 19.5 1.1 1 0 0 1 1 1 0 Spt20 family PAXIP1_C PF15364.6 ORY98188.1 - 0.16 12.3 3.3 0.23 11.8 3.3 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Lin-8 PF03353.15 ORY98188.1 - 4.7 6.7 9.9 6.3 6.3 9.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Roughex PF06020.11 ORY98188.1 - 8 5.5 7.5 14 4.7 7.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Rhodanese PF00581.20 ORY98189.1 - 1.3e-16 61.0 0.0 1.6e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Oxidored_FMN PF00724.20 ORY98190.1 - 8.6e-104 347.5 0.0 9.8e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SNF2_N PF00176.23 ORY98191.1 - 1e-47 162.6 0.1 1.5e-47 162.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY98191.1 - 2.2e-18 66.6 0.0 6.1e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 ORY98191.1 - 7.7e-07 28.6 0.0 3.2e-06 26.5 0.0 1.9 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 ORY98191.1 - 1.8e-05 24.6 0.0 0.00026 20.7 0.0 2.2 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 ORY98191.1 - 4.4e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY98191.1 - 0.0033 16.6 0.9 0.031 13.4 0.9 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Xan_ur_permease PF00860.20 ORY98192.1 - 2.4e-49 168.1 27.2 2.8e-48 164.6 27.2 2.0 1 1 0 1 1 1 1 Permease family Wzz PF02706.15 ORY98192.1 - 0.26 11.6 1.3 0.66 10.3 0.1 2.4 2 0 0 2 2 2 0 Chain length determinant protein TMIE PF16038.5 ORY98192.1 - 0.49 10.3 0.1 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 TMIE protein MFS_MOT1 PF16983.5 ORY98192.1 - 1.1 9.6 17.5 1.1 9.7 0.9 3.9 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily UPF0242 PF06785.11 ORY98193.1 - 0.026 14.6 0.6 0.058 13.5 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Abhydrolase_3 PF07859.13 ORY98196.1 - 1.7e-46 158.8 0.0 2.3e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY98196.1 - 1.9e-11 43.4 0.0 4.3e-11 42.3 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY98196.1 - 0.0068 15.3 0.0 0.012 14.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Eno-Rase_NADH_b PF12242.8 ORY98196.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_2 PF02230.16 ORY98196.1 - 0.082 12.7 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ank_2 PF12796.7 ORY98197.1 - 1.3e-34 118.6 4.3 3.6e-13 49.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY98197.1 - 1.2e-32 111.8 2.9 1.7e-08 34.8 0.1 4.9 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY98197.1 - 2.9e-27 94.4 4.8 1.8e-08 34.5 0.0 5.0 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY98197.1 - 2.5e-21 73.5 3.0 2.5e-05 24.3 0.0 7.2 7 1 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 ORY98197.1 - 6.1e-20 70.7 8.6 8.6e-06 26.0 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat zf-C2H2 PF00096.26 ORY98198.1 - 1.5e-05 25.2 14.6 0.0079 16.6 0.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY98198.1 - 0.0011 19.3 4.5 0.0011 19.3 4.5 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY98198.1 - 0.032 15.1 2.6 0.032 15.1 2.6 3.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY98198.1 - 0.075 13.0 0.8 0.075 13.0 0.8 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORY98198.1 - 0.79 9.5 7.2 0.47 10.3 1.8 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type DENN PF02141.21 ORY98199.1 - 1.6e-34 119.5 0.0 5.4e-25 88.4 0.1 2.5 1 1 1 2 2 2 2 DENN (AEX-3) domain dDENN PF03455.19 ORY98199.1 - 1.6e-12 47.2 2.2 3.9e-12 46.0 2.2 1.7 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.22 ORY98199.1 - 0.0027 17.5 5.5 0.0061 16.4 5.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) uDENN PF03456.18 ORY98199.1 - 0.055 14.2 2.0 0.3 11.9 0.3 2.8 2 1 0 2 2 2 0 uDENN domain PHD_4 PF16866.5 ORY98199.1 - 3.8 7.7 6.9 9.5 6.4 6.9 1.6 1 0 0 1 1 1 0 PHD-finger Allantoicase PF03561.15 ORY98200.1 - 2.2e-44 150.9 0.0 2.4e-25 89.2 0.0 2.4 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 ORY98200.1 - 0.0043 17.2 1.2 0.013 15.7 0.1 2.3 3 0 0 3 3 3 1 F5/8 type C domain ABC_membrane PF00664.23 ORY98201.1 - 1.2e-62 212.1 34.1 1.9e-42 145.8 7.3 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY98201.1 - 8.8e-52 175.3 0.0 9.9e-31 107.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY98201.1 - 1.5e-10 40.9 1.2 0.00015 21.3 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 ORY98201.1 - 1.6e-06 27.4 0.0 0.0037 16.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 ORY98201.1 - 9.2e-06 25.3 0.7 0.06 13.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY98201.1 - 9.6e-06 26.2 0.1 0.024 15.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY98201.1 - 4.5e-05 23.1 0.0 0.12 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORY98201.1 - 0.0001 21.6 0.0 0.023 14.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 ORY98201.1 - 0.00012 21.4 1.7 0.19 10.9 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain DUF87 PF01935.17 ORY98201.1 - 0.00015 21.9 4.8 0.035 14.2 0.0 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 ORY98201.1 - 0.00018 21.5 0.1 0.031 14.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 ORY98201.1 - 0.00028 21.0 0.1 0.049 13.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORY98201.1 - 0.0012 18.9 1.3 0.69 10.0 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY98201.1 - 0.002 18.5 0.3 1.8 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY98201.1 - 0.0026 18.0 4.9 0.29 11.4 0.4 3.2 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY98201.1 - 0.0036 16.7 0.0 0.77 9.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 ORY98201.1 - 0.0063 16.3 0.7 15 5.3 0.0 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein cobW PF02492.19 ORY98201.1 - 0.0088 15.7 3.1 0.069 12.7 0.5 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 ORY98201.1 - 0.0096 15.8 0.3 26 4.5 0.3 3.5 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY98201.1 - 0.011 15.3 0.2 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 ORY98201.1 - 0.013 15.6 0.8 0.47 10.5 0.1 2.6 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 ORY98201.1 - 0.019 14.9 2.3 2.9 7.8 0.1 3.0 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.9 ORY98201.1 - 0.02 13.8 0.3 4.9 5.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 ORY98201.1 - 0.047 13.4 0.9 12 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ORY98201.1 - 0.082 12.6 0.3 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY98201.1 - 0.082 13.4 0.9 8.9 6.9 0.4 2.8 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 ORY98201.1 - 0.095 12.6 0.5 5.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.12 ORY98201.1 - 0.1 12.1 0.3 14 5.0 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.22 ORY98201.1 - 0.18 12.2 0.5 43 4.5 0.1 3.1 3 0 0 3 3 3 0 RNA helicase AAA PF00004.29 ORY98201.1 - 0.2 12.1 1.2 21 5.6 0.1 3.5 4 1 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ORY98201.1 - 0.24 11.1 1.4 3.1 7.5 0.1 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_15 PF13175.6 ORY98201.1 - 0.36 10.5 0.6 18 4.9 0.4 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 ORY98201.1 - 0.58 9.9 3.5 9.2 6.0 0.6 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ORY98201.1 - 7.6 6.4 5.3 39 4.1 0.2 2.7 3 0 0 3 3 2 0 NTPase MFS_1 PF07690.16 ORY98203.1 - 2e-34 119.1 24.4 2e-34 119.1 24.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY98203.1 - 8e-05 22.1 3.8 8e-05 22.1 3.8 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Mtp PF03821.16 ORY98204.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Herpes_teg_N PF04843.12 ORY98206.1 - 0.095 12.4 0.1 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region p450 PF00067.22 ORY98209.1 - 3.3e-30 105.3 0.0 4.2e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 ORY98209.1 - 0.18 12.0 0.2 1.5 9.0 0.1 2.4 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Septin PF00735.18 ORY98210.1 - 2.4e-110 368.2 0.1 3.9e-110 367.6 0.1 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 ORY98210.1 - 2.3e-08 33.8 1.1 6.3e-06 25.9 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY98210.1 - 1.1e-07 31.9 0.0 2.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY98210.1 - 5.5e-07 29.6 1.1 1.9e-05 24.6 0.4 2.8 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORY98210.1 - 0.00026 21.2 0.1 0.00073 19.7 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORY98210.1 - 0.00072 19.8 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ORY98210.1 - 0.0024 17.7 0.1 0.014 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY98210.1 - 0.0025 18.0 0.8 0.0069 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 ORY98210.1 - 0.0031 16.9 0.1 0.0063 15.9 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 ORY98210.1 - 0.0043 16.7 0.1 0.016 14.8 0.1 2.0 1 1 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.18 ORY98210.1 - 0.0051 16.2 1.8 0.014 14.8 0.1 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family IIGP PF05049.13 ORY98210.1 - 0.0057 15.8 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 ORY98210.1 - 0.0074 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 ORY98210.1 - 0.0089 16.4 0.3 0.023 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 ORY98210.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 ORY98210.1 - 0.021 15.3 0.2 0.092 13.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 ORY98210.1 - 0.022 14.5 1.7 0.033 13.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 ORY98210.1 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 ORY98210.1 - 0.029 13.9 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 ORY98210.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORY98210.1 - 0.034 13.9 0.1 3.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 ORY98210.1 - 0.051 13.6 4.7 4.2 7.4 0.1 3.0 2 1 1 3 3 3 0 Dynamin family AAA_23 PF13476.6 ORY98210.1 - 0.062 13.8 0.0 0.062 13.8 0.0 2.3 2 1 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 ORY98210.1 - 0.064 13.0 0.8 1.4 8.6 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 ORY98210.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 ORY98210.1 - 0.11 12.4 1.0 0.65 9.9 0.3 2.3 2 0 0 2 2 2 0 NTPase Glycos_transf_1 PF00534.20 ORY98211.1 - 3.5e-28 98.3 0.0 2.8e-26 92.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY98211.1 - 6.7e-13 49.2 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY98211.1 - 1e-12 48.4 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORY98211.1 - 1.9e-05 25.2 0.0 4.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ORY98211.1 - 0.0024 18.2 0.0 0.0067 16.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 ORY98211.1 - 0.088 12.8 1.8 1.1 9.3 1.8 2.4 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus LSM PF01423.22 ORY98212.1 - 1.4e-16 60.0 0.0 1.7e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SBF PF01758.16 ORY98213.1 - 1.1e-54 185.1 12.6 1.1e-54 185.1 12.6 2.2 3 0 0 3 3 3 1 Sodium Bile acid symporter family DUF2721 PF11026.8 ORY98213.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) Ras PF00071.22 ORY98214.1 - 3.5e-56 189.3 0.1 4.2e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY98214.1 - 1.2e-35 122.3 0.0 2e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY98214.1 - 9.9e-15 54.4 0.0 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY98214.1 - 7.8e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY98214.1 - 8.4e-05 22.2 0.0 0.00048 19.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY98214.1 - 8.8e-05 22.0 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY98214.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY98214.1 - 0.00027 20.9 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 ORY98214.1 - 0.021 15.0 0.0 1.8 8.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ORY98214.1 - 0.097 12.1 0.1 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 ORY98214.1 - 0.11 12.1 0.0 7 6.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 ORY98214.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_hydro_18 PF00704.28 ORY98215.1 - 3.6e-70 237.2 3.6 4.2e-70 237.0 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_20 PF00686.19 ORY98215.1 - 0.069 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Starch binding domain Erf4 PF10256.9 ORY98216.1 - 1.5e-18 67.0 0.2 1.7e-18 66.8 0.2 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Pam17 PF08566.10 ORY98217.1 - 8.8e-57 191.5 0.1 1.1e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.16 ORY98217.1 - 0.016 14.4 0.1 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Glt_symporter PF03616.14 ORY98217.1 - 0.048 12.3 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter TMEM154 PF15102.6 ORY98218.1 - 0.00071 19.5 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Alpha_E1_glycop PF01589.16 ORY98218.1 - 0.0042 15.8 0.1 0.0059 15.3 0.1 1.1 1 0 0 1 1 1 1 Alphavirus E1 glycoprotein CYYR1 PF10873.8 ORY98218.1 - 0.029 14.8 0.8 0.041 14.3 0.0 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TMEM51 PF15345.6 ORY98218.1 - 0.043 13.7 6.3 0.22 11.4 6.3 2.1 1 1 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 ORY98218.1 - 0.047 14.6 4.0 1 10.3 4.0 2.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SUIM_assoc PF16619.5 ORY98218.1 - 1.4 9.1 15.4 0.26 11.4 0.6 3.3 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 GARS_A PF01071.19 ORY98221.1 - 6.8e-85 283.7 1.0 4.4e-84 281.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 ORY98221.1 - 1.9e-38 132.0 0.0 7.2e-38 130.2 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 ORY98221.1 - 2.4e-32 111.6 0.2 5e-31 107.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ORY98221.1 - 7.4e-29 99.9 0.5 1.7e-28 98.7 0.5 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 ORY98221.1 - 3.6e-14 53.2 0.9 3.6e-14 53.2 0.9 2.3 3 0 0 3 3 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 ORY98221.1 - 6.9e-06 25.7 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 ORY98221.1 - 2.4e-05 24.0 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY98221.1 - 3.8e-05 23.8 0.1 0.00012 22.1 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 ORY98221.1 - 0.0038 16.8 0.1 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 ORY98221.1 - 0.0046 16.6 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY98221.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 ORY98221.1 - 0.17 11.1 0.0 0.54 9.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Helicase_C_2 PF13307.6 ORY98222.1 - 3.1e-54 183.7 0.0 6.4e-54 182.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ORY98222.1 - 5.9e-46 156.3 1.7 1.4e-45 155.0 1.7 1.6 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 ORY98222.1 - 7.6e-06 25.8 0.0 6.7e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY98222.1 - 2.9e-05 24.2 0.1 0.0084 16.1 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY98222.1 - 0.013 14.2 0.7 0.023 13.4 0.7 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain HBB PF06777.11 ORY98222.1 - 0.029 14.1 0.2 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Helical and beta-bridge domain Cadherin_C PF01049.17 ORY98222.1 - 0.039 14.3 0.8 0.097 13.0 0.8 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic region PhoH PF02562.16 ORY98222.1 - 0.16 11.4 0.6 12 5.3 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein PBP1_TM PF14812.6 ORY98222.1 - 0.68 10.3 4.9 1.8 9.0 0.6 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thioredoxin_4 PF13462.6 ORY98223.1 - 7.1e-12 45.8 0.0 9.5e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ORY98223.1 - 0.0036 17.1 5.1 0.41 10.4 0.9 2.6 1 1 1 2 2 2 2 DSBA-like thioredoxin domain DUF1380 PF07128.12 ORY98223.1 - 0.16 12.1 0.1 0.22 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1380) F-box-like PF12937.7 ORY98228.1 - 0.00041 20.2 0.4 0.0032 17.3 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY98228.1 - 0.43 10.5 2.4 0.4 10.6 0.2 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 ORY98229.1 - 0.004 17.0 0.1 0.004 17.0 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY98229.1 - 0.085 12.8 0.2 0.45 10.4 0.2 2.3 1 0 0 1 1 1 0 F-box domain Nucleo_P87 PF07267.11 ORY98230.1 - 0.11 11.3 1.5 0.16 10.8 1.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Astro_capsid_p PF12226.8 ORY98230.1 - 2 7.5 5.2 2.9 7.0 5.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 ORY98230.1 - 5.9 6.1 6.7 8.4 5.6 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein MAS20 PF02064.15 ORY98232.1 - 1.7e-42 144.5 2.1 1.7e-42 144.5 2.1 2.4 2 1 0 2 2 2 1 MAS20 protein import receptor zf-MYND PF01753.18 ORY98232.1 - 5.6e-05 23.1 11.5 9.6e-05 22.4 11.5 1.4 1 0 0 1 1 1 1 MYND finger BCAS2 PF05700.11 ORY98232.1 - 0.0081 15.9 0.2 0.0081 15.9 0.2 1.7 2 0 0 2 2 2 1 Breast carcinoma amplified sequence 2 (BCAS2) FbpA PF05833.11 ORY98232.1 - 0.04 12.7 3.2 0.31 9.8 0.9 2.1 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) zf-C3HC4 PF00097.25 ORY98232.1 - 0.2 11.6 3.9 0.42 10.5 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rhodanese_C PF12368.8 ORY98232.1 - 3.1 8.3 8.2 6.3 7.3 8.2 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Gag_p12 PF01141.18 ORY98233.1 - 0.0088 16.4 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 Gag polyprotein, inner coat protein p12 adh_short PF00106.25 ORY98235.1 - 1.9e-35 122.1 0.1 2.7e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY98235.1 - 1.4e-20 73.8 0.2 2e-20 73.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY98235.1 - 1.6e-09 37.9 0.1 2.4e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY98235.1 - 0.00061 19.3 0.0 0.00089 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY98235.1 - 0.012 14.8 0.1 0.023 13.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY98235.1 - 0.017 14.5 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peripla_BP_6 PF13458.6 ORY98235.1 - 0.02 14.6 0.2 0.043 13.5 0.1 1.3 1 1 0 1 1 1 0 Periplasmic binding protein Peptidase_C80 PF11713.8 ORY98235.1 - 0.025 14.8 0.1 0.084 13.1 0.0 1.9 2 0 0 2 2 2 0 Peptidase C80 family 3Beta_HSD PF01073.19 ORY98235.1 - 0.026 13.5 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_tran_WecB PF03808.13 ORY98235.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF953 PF06110.11 ORY98236.1 - 5.4e-27 93.8 0.0 6e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 ORY98236.1 - 0.055 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin 4F5 PF04419.14 ORY98237.1 - 4.3e-06 27.5 12.8 7.1e-06 26.8 12.8 1.3 1 0 0 1 1 1 1 4F5 protein family CDPS PF16715.5 ORY98237.1 - 0.00053 19.7 0.0 0.00068 19.4 0.0 1.0 1 0 0 1 1 1 1 Cyclodipeptide synthase zf-met2 PF12907.7 ORY98237.1 - 0.0037 17.4 0.2 0.0059 16.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding zf-Di19 PF05605.12 ORY98237.1 - 0.014 15.7 0.3 0.02 15.2 0.3 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORY98237.1 - 0.049 14.5 0.2 0.072 14.0 0.2 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Sel_put PF04328.13 ORY98237.1 - 0.09 12.8 0.7 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Selenoprotein, putative Mu-like_Com PF10122.9 ORY98237.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-C2H2 PF00096.26 ORY98237.1 - 0.18 12.3 0.2 0.27 11.8 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type DcpS_C PF11969.8 ORY98238.1 - 6e-25 88.0 0.2 7.5e-25 87.6 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORY98238.1 - 5.7e-12 46.2 2.7 2.3e-11 44.3 2.7 1.8 1 1 0 1 1 1 1 HIT domain Ribosomal_S19e PF01090.19 ORY98238.1 - 0.062 13.0 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e Pkinase PF00069.25 ORY98239.1 - 6.3e-73 245.4 0.0 1.3e-72 244.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98239.1 - 7.4e-35 120.5 0.0 1.9e-34 119.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY98239.1 - 0.0031 16.4 0.0 0.0063 15.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY98239.1 - 0.0088 15.4 0.7 2.6 7.3 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 ORY98239.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ndc1_Nup PF09531.10 ORY98240.1 - 0.19 10.4 2.6 0.23 10.1 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AP3D1 PF06375.11 ORY98244.1 - 0.25 11.6 5.6 0.26 11.5 5.6 1.0 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 ORY98244.1 - 0.32 11.1 2.5 0.32 11.1 2.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4519 PF15012.6 ORY98244.1 - 2.8 8.2 11.0 3.7 7.8 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_S9 PF00380.19 ORY98246.1 - 5.1e-29 101.3 0.1 6e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Arginase PF00491.21 ORY98247.1 - 1e-90 304.0 0.0 1.4e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ORY98247.1 - 0.042 14.1 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain HSP70 PF00012.20 ORY98446.1 - 5.6e-262 870.3 7.1 6.4e-262 870.1 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY98446.1 - 4.3e-16 58.6 0.2 8.3e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORY98446.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORY98446.1 - 0.011 15.0 0.2 0.031 13.5 0.2 1.8 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 ORY98446.1 - 0.13 11.5 0.5 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 StbA protein Xpo1 PF08389.12 ORY98447.1 - 1.7e-22 80.1 2.1 5.7e-22 78.4 0.1 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 ORY98447.1 - 5.9e-10 38.9 1.9 2.5e-09 36.9 0.5 2.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Importin_rep PF18773.1 ORY98447.1 - 0.00061 19.4 0.2 0.0014 18.3 0.2 1.7 1 0 0 1 1 1 1 Importin 13 repeat Lipase_GDSL_2 PF13472.6 ORY98448.1 - 0.0018 18.7 0.0 0.0093 16.4 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF5530 PF17670.1 ORY98448.1 - 0.0087 15.8 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5530) Glucosamine_iso PF01182.20 ORY98448.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Nt_Gln_amidase PF09764.9 ORY98449.1 - 1.5e-62 210.5 0.3 1.8e-62 210.2 0.3 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase TFIIA PF03153.13 ORY98450.1 - 0.0036 17.4 11.8 0.0052 16.8 11.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.12 ORY98450.1 - 1.8 7.5 3.3 2.7 6.9 3.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Galactosyl_T PF01762.21 ORY98451.1 - 9.2e-13 48.4 0.0 1.8e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 ORY98451.1 - 3.1e-08 33.8 12.2 1.1e-07 31.9 12.2 1.8 1 1 0 1 1 1 1 N-glycosylation protein FAD_binding_2 PF00890.24 ORY98452.1 - 6.6e-80 269.2 0.3 9.5e-80 268.7 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 ORY98452.1 - 1.1e-22 80.0 0.1 9.8e-22 76.9 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 ORY98452.1 - 3.9e-14 53.0 0.4 8.8e-14 51.8 0.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY98452.1 - 2.6e-09 36.9 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY98452.1 - 9.6e-09 35.4 0.1 4.4e-08 33.2 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY98452.1 - 1e-06 28.2 0.4 4.5e-06 26.1 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY98452.1 - 2.6e-05 23.1 2.4 0.00036 19.4 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ORY98452.1 - 6.9e-05 22.2 0.2 0.021 14.1 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 ORY98452.1 - 0.00088 18.5 1.0 0.0042 16.2 0.1 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY98452.1 - 0.0043 16.3 0.0 0.078 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY98452.1 - 0.008 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY98452.1 - 0.032 13.5 0.1 0.061 12.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_60s PF00428.19 ORY98452.1 - 0.032 14.8 6.5 0.72 10.5 5.2 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amino_oxidase PF01593.24 ORY98452.1 - 0.035 13.4 0.3 0.12 11.6 0.0 2.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ORY98452.1 - 0.051 13.6 0.5 1.2 9.1 0.2 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORY98452.1 - 0.073 13.6 0.9 1.9 9.1 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 ORY98452.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Kinesin PF00225.23 ORY98453.1 - 4.6e-113 377.5 0.1 7.4e-113 376.8 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 ORY98453.1 - 1.8e-46 158.6 0.9 7.3e-46 156.6 0.9 2.1 1 0 0 1 1 1 1 Kinesin-associated DUF3694 PF12473.8 ORY98453.1 - 6.9e-38 130.7 0.0 2.1e-37 129.2 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 ORY98453.1 - 4e-26 91.7 0.0 9.5e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 ORY98453.1 - 2.7e-16 60.0 0.0 9.4e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 ORY98453.1 - 3.7e-08 33.7 0.2 1e-07 32.3 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 ORY98453.1 - 3.5e-06 27.3 0.1 1.7e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 ORY98453.1 - 0.0012 19.2 0.0 0.0035 17.6 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH_9 PF15410.6 ORY98453.1 - 0.025 14.9 0.1 0.11 12.9 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain DUF3105 PF11303.8 ORY98453.1 - 0.16 12.1 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) MPC PF03650.13 ORY98454.1 - 8.6e-45 151.4 0.5 9.5e-45 151.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 ORY98454.1 - 0.016 15.2 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange UQ_con PF00179.26 ORY98455.1 - 1.1e-48 164.5 0.1 1.2e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY98455.1 - 0.11 12.8 1.9 0.16 12.2 1.9 1.5 1 1 0 1 1 1 0 RWD domain Metallophos PF00149.28 ORY98458.1 - 2.5e-37 129.4 0.0 4.3e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Acyltransferase PF01553.21 ORY98459.1 - 1.9e-08 34.0 0.0 3.2e-07 30.0 0.0 2.6 2 1 0 2 2 2 1 Acyltransferase Velvet PF11754.8 ORY98461.1 - 9.3e-37 127.3 5.4 2.9e-27 96.2 0.5 4.0 2 2 1 3 3 3 2 Velvet factor MAS20 PF02064.15 ORY98463.1 - 5.1e-17 62.2 0.1 5.1e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 MAS20 protein import receptor zf-MYND PF01753.18 ORY98463.1 - 0.00045 20.2 8.9 0.00095 19.2 8.9 1.6 1 0 0 1 1 1 1 MYND finger zf-RING_4 PF14570.6 ORY98463.1 - 0.018 14.8 1.3 0.058 13.2 1.3 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Siva PF05458.12 ORY98463.1 - 0.024 14.4 2.0 0.043 13.5 2.0 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) SET PF00856.28 ORY98463.1 - 0.069 13.5 0.8 0.18 12.2 0.8 1.8 1 1 0 1 1 1 0 SET domain Coronavirus_5 PF05528.11 ORY98463.1 - 0.25 11.3 1.5 0.69 9.9 1.5 1.7 1 0 0 1 1 1 0 Coronavirus gene 5 protein Ribosomal_L2_C PF03947.18 ORY98464.1 - 1.5e-44 151.2 3.7 2.4e-44 150.6 3.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY98464.1 - 4.5e-15 55.4 0.1 1e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Bromodomain PF00439.25 ORY98465.1 - 7.4e-16 58.0 0.5 1.8e-15 56.7 0.5 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 ORY98465.1 - 2.7e-11 43.3 0.4 1.3e-10 41.1 0.0 2.4 3 0 0 3 3 3 1 Bromodomain associated Bromo_TP_like PF17027.5 ORY98465.1 - 0.048 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Histone-fold protein DUF4192 PF13830.6 ORY98465.1 - 5.9 6.8 5.4 13 5.7 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) C2 PF00168.30 ORY98466.1 - 7.9e-08 32.5 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain HemX PF04375.14 ORY98466.1 - 0.14 11.4 3.6 0.22 10.8 3.6 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cwf_Cwc_15 PF04889.12 ORY98466.1 - 0.16 11.7 29.7 0.28 10.9 29.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zip PF02535.22 ORY98466.1 - 0.23 10.6 17.9 0.33 10.1 17.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 ORY98466.1 - 0.73 9.1 37.3 1 8.6 37.3 1.3 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 ORY98466.1 - 1.2 8.6 20.0 1.6 8.2 20.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 ORY98466.1 - 1.5 7.0 40.2 1.8 6.7 40.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 ORY98466.1 - 1.5 8.1 26.6 2.5 7.4 26.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CKAP2_C PF15297.6 ORY98466.1 - 5.6 5.9 22.2 8.8 5.3 22.2 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF913 PF06025.12 ORY98466.1 - 9.7 5.1 13.3 14 4.5 13.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim17 PF02466.19 ORY98467.1 - 1.6e-30 105.8 7.9 2e-30 105.4 7.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ferric_reduct PF01794.19 ORY98468.1 - 7.5e-21 74.5 8.5 7.5e-21 74.5 8.5 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY98468.1 - 1e-14 54.9 0.0 2.5e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY98468.1 - 6.4e-06 26.2 0.1 6.5e-05 23.0 0.2 2.5 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY98468.1 - 0.013 16.2 0.7 0.1 13.3 0.0 2.5 2 1 1 3 3 3 0 Oxidoreductase NAD-binding domain DUF334 PF03904.13 ORY98468.1 - 0.072 12.6 0.4 2.8 7.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Corona_M PF01635.18 ORY98468.1 - 0.16 11.2 4.8 0.33 10.2 4.8 1.5 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein GATA PF00320.27 ORY98469.1 - 4.7e-24 83.7 23.5 2.4e-13 49.4 4.4 2.9 3 0 0 3 3 3 2 GATA zinc finger DUF1752 PF08550.10 ORY98469.1 - 1.1e-10 41.2 2.1 2.1e-10 40.2 2.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 ORY98469.1 - 0.00053 20.0 2.3 0.22 11.7 0.1 2.7 2 0 0 2 2 2 2 Zinc ribbon domain DZR PF12773.7 ORY98469.1 - 0.0018 18.3 3.7 0.008 16.2 3.7 2.2 1 1 0 1 1 1 1 Double zinc ribbon Alkyl_sulf_dimr PF14863.6 ORY98469.1 - 0.016 15.6 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TF_Zn_Ribbon PF08271.12 ORY98469.1 - 0.018 14.5 8.5 0.14 11.7 0.8 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 ORY98469.1 - 0.028 14.8 0.3 3.2 8.2 0.1 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar Auto_anti-p27 PF06677.12 ORY98469.1 - 0.035 14.3 4.9 3.2 8.0 0.5 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 ORY98469.1 - 0.037 13.9 4.0 3.4 7.6 0.2 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 ORY98469.1 - 0.53 10.2 8.5 2.6 8.0 0.4 3.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 ORY98469.1 - 0.67 9.4 12.8 1.5 8.3 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain DNA_pol_phi PF04931.13 ORY98469.1 - 0.81 7.7 8.7 0.69 7.9 6.7 1.8 2 0 0 2 2 2 0 DNA polymerase phi Vps36-NZF-N PF16988.5 ORY98469.1 - 9.4 5.7 14.6 1.8 8.0 0.3 4.0 2 2 2 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cwf_Cwc_15 PF04889.12 ORY98469.1 - 9.8 5.8 19.3 1.4 8.5 5.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rib_recp_KP_reg PF05104.12 ORY98470.1 - 0.0059 17.7 15.7 0.01 16.9 15.7 1.4 1 0 0 1 1 1 1 Ribosome receptor lysine/proline rich region EMC3_TMCO1 PF01956.16 ORY98470.1 - 0.49 10.1 2.6 0.69 9.6 2.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4551 PF15087.6 ORY98470.1 - 5.5 5.7 13.1 6.3 5.5 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BP28CT PF08146.12 ORY98471.1 - 2e-41 141.5 1.8 2e-41 141.5 1.8 3.8 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 ORY98471.1 - 1.3e-25 90.0 6.4 9.6e-25 87.2 0.9 5.2 4 2 1 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 ORY98471.1 - 3.9e-09 36.8 9.7 0.0027 18.1 0.0 7.7 7 1 0 7 7 7 2 HEAT repeats HEAT PF02985.22 ORY98471.1 - 7.8e-07 28.8 12.4 0.11 12.8 0.0 8.4 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 ORY98471.1 - 2.2e-06 27.8 3.0 0.0015 18.6 0.1 4.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 ORY98471.1 - 1.6e-05 24.9 1.1 0.025 14.5 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 ORY98471.1 - 0.0029 18.1 8.9 9.3 6.9 0.0 8.1 7 0 0 7 7 7 1 HEAT-like repeat DDE_Tnp_IS1595 PF12762.7 ORY98471.1 - 0.095 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain HLH PF00010.26 ORY98472.1 - 7.9e-11 41.8 0.1 2.2e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.18 ORY98472.1 - 0.0097 16.2 0.6 0.032 14.5 0.6 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family GDA1_CD39 PF01150.17 ORY98475.1 - 7.4e-117 390.6 0.0 1.1e-116 390.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.25 ORY98477.1 - 6e-77 258.6 0.0 9.2e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98477.1 - 1.9e-35 122.4 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98477.1 - 5.7e-08 32.4 0.0 4.5e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY98477.1 - 9.2e-05 22.1 0.3 0.00021 20.9 0.3 1.7 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY98477.1 - 0.00021 20.4 0.1 0.00032 19.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY98477.1 - 0.0026 17.7 1.0 0.029 14.3 0.9 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY98477.1 - 0.0032 16.9 0.1 0.006 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4096 PF13340.6 ORY98477.1 - 0.059 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Rib_recp_KP_reg PF05104.12 ORY98477.1 - 0.46 11.5 8.7 0.77 10.8 8.7 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region MgtE PF01769.16 ORY98478.1 - 8.8e-43 145.6 27.1 1.7e-24 86.6 4.5 3.6 4 0 0 4 4 4 2 Divalent cation transporter Phage_holin_3_3 PF16083.5 ORY98478.1 - 0.031 14.4 0.4 0.031 14.4 0.4 3.9 5 0 0 5 5 5 0 LydA holin phage, holin superfamily III zf-H2C2_2 PF13465.6 ORY98479.1 - 2.9e-11 43.3 17.6 4.6e-05 23.6 2.6 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY98479.1 - 3.3e-08 33.5 25.5 0.00041 20.6 0.5 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY98479.1 - 3.8e-05 24.2 13.7 0.06 14.0 0.1 4.4 2 2 2 4 4 4 2 FOXP coiled-coil domain Zap1_zf2 PF18217.1 ORY98479.1 - 4.2e-05 23.4 0.3 4.2e-05 23.4 0.3 2.7 2 0 0 2 2 2 1 Zap1 zinc finger 2 zf-C2H2_4 PF13894.6 ORY98479.1 - 0.0002 21.9 21.0 0.033 15.0 0.5 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY98479.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 3.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY98479.1 - 0.0076 16.5 3.2 0.062 13.6 2.9 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY98479.1 - 0.0096 16.1 5.1 2.8 8.0 1.0 3.2 1 1 2 3 3 3 3 Aberrant zinc-finger Adeno_PX PF05829.12 ORY98479.1 - 0.12 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) DUF3767 PF12597.8 ORY98481.1 - 2e-32 111.0 0.1 2.7e-32 110.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Perilipin PF03036.16 ORY98482.1 - 2.5e-06 26.8 6.1 3.5e-06 26.3 0.0 3.2 1 1 1 3 3 3 1 Perilipin family Apolipoprotein PF01442.18 ORY98482.1 - 0.0035 17.2 5.0 0.12 12.2 5.0 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain E1-E2_ATPase PF00122.20 ORY98483.1 - 1.1e-46 158.7 3.9 1.1e-46 158.7 3.9 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORY98483.1 - 5.8e-25 88.8 0.4 1.2e-24 87.7 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY98483.1 - 7.2e-13 48.0 0.0 2.5e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY98483.1 - 0.0027 17.5 0.2 0.1 12.3 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORY98483.1 - 0.003 17.3 7.0 0.003 17.3 7.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus HAD PF12710.7 ORY98483.1 - 0.0038 17.6 0.1 0.0094 16.4 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 ORY98484.1 - 3.4e-33 115.2 21.6 3.5e-21 75.6 10.6 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY98484.1 - 1.5e-30 106.4 32.9 1.9e-30 106.0 32.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 ORY98484.1 - 0.00041 19.1 14.5 0.00052 18.8 9.8 2.1 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 ORY98484.1 - 0.0011 17.9 14.9 0.019 13.8 0.1 2.3 1 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 ORY98484.1 - 2.6 6.2 17.5 5.7 5.1 13.5 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CoatB PF10389.9 ORY98484.1 - 8.8 6.3 7.2 0.48 10.3 0.5 2.6 2 1 0 2 2 2 0 Bacteriophage coat protein B Fungal_trans PF04082.18 ORY98485.1 - 2.4e-10 39.9 0.3 8.1e-10 38.2 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CP2 PF04516.15 ORY98485.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 CP2 transcription factor RSN1_7TM PF02714.15 ORY98486.1 - 3.3e-62 210.3 22.3 3.3e-62 210.3 22.3 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY98486.1 - 1.4e-16 60.6 4.4 1.4e-16 60.6 4.4 4.0 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY98486.1 - 2e-15 57.5 0.2 4.3e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.25 ORY98487.1 - 4.4e-50 170.5 0.0 6.8e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98487.1 - 1.4e-23 83.6 0.0 3.8e-23 82.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY98487.1 - 0.00017 21.6 0.1 0.00017 21.6 0.1 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORY98487.1 - 0.012 15.3 2.7 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY98487.1 - 0.051 12.5 0.0 0.051 12.5 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Spt20 PF12090.8 ORY98487.1 - 0.12 11.9 14.3 0.27 10.8 14.3 1.7 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 ORY98487.1 - 0.4 8.9 15.7 0.62 8.3 15.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase_fungal PF17667.1 ORY98487.1 - 2.1 7.0 4.5 4 6.1 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF908 PF06012.12 ORY98487.1 - 2.2 7.6 15.7 3.8 6.8 15.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Ndc1_Nup PF09531.10 ORY98487.1 - 2.7 6.6 12.2 4.1 6.0 12.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 ORY98487.1 - 3 7.4 15.5 0.32 10.6 9.3 2.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Arrestin_N PF00339.29 ORY98488.1 - 9.4e-09 35.5 0.0 1e-07 32.1 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY98488.1 - 4.9e-06 27.0 0.3 0.0051 17.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY98488.1 - 0.01 15.5 0.0 0.069 12.8 0.0 2.3 1 1 1 2 2 2 0 Arrestin_N terminal like RTP1_C2 PF10304.9 ORY98488.1 - 0.93 9.3 0.0 0.93 9.3 0.0 2.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 2 Motile_Sperm PF00635.26 ORY98489.1 - 8.1e-24 83.6 2.7 4.6e-23 81.1 0.1 2.3 2 0 0 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 ORY98489.1 - 0.022 15.0 0.0 0.065 13.4 0.0 1.8 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NAD_binding_10 PF13460.6 ORY98490.1 - 1.5e-11 44.6 0.0 4.5e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY98490.1 - 4.2e-06 26.4 0.0 5.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY98490.1 - 0.00013 22.4 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 ORY98490.1 - 0.00082 18.6 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 ORY98490.1 - 0.0014 18.9 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 ORY98490.1 - 0.0025 17.8 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ORY98490.1 - 0.036 13.5 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 ORY98490.1 - 0.062 13.9 0.1 0.14 12.8 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 ORY98490.1 - 0.064 12.3 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY98490.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 ORY98490.1 - 0.11 12.6 0.4 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 ORY98490.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NUC173 PF08161.12 ORY98491.1 - 2.1e-65 220.2 2.8 3.8e-62 209.6 0.0 4.3 4 1 1 5 5 5 2 NUC173 domain Abhydrolase_9_N PF15420.6 ORY98491.1 - 0.11 12.5 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DNA_pol_phi PF04931.13 ORY98491.1 - 9.6 4.2 21.0 0.056 11.6 3.5 3.2 3 0 0 3 3 3 0 DNA polymerase phi Usp PF00582.26 ORY98493.1 - 4.8e-21 75.7 0.0 6.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Peptidase_S9 PF00326.21 ORY98494.1 - 2.1e-44 151.5 0.2 3.3e-44 150.9 0.2 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY98494.1 - 3e-06 27.0 0.2 6.9e-05 22.6 0.1 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ORY98494.1 - 0.00016 21.4 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 ORY98494.1 - 0.00042 21.0 0.0 0.00048 20.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY98494.1 - 0.011 15.3 0.0 0.038 13.5 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY98494.1 - 0.046 13.4 0.3 0.13 11.8 0.1 1.7 1 1 0 2 2 2 0 alpha/beta hydrolase fold DPPIV_N PF00930.21 ORY98495.1 - 8.1e-26 90.6 0.6 9.4e-26 90.4 0.6 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DPPIV_N PF00930.21 ORY98496.1 - 4e-18 65.3 0.0 5e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region TMEM171 PF15471.6 ORY98497.1 - 0.012 14.6 6.3 0.02 13.9 6.3 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Mito_fiss_reg PF05308.11 ORY98497.1 - 0.086 12.9 3.7 0.14 12.2 3.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 ORY98497.1 - 0.55 9.7 4.9 0.84 9.1 4.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PI3K_1B_p101 PF10486.9 ORY98497.1 - 1.4 6.6 3.4 1.7 6.3 3.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PAS_9 PF13426.7 ORY98498.1 - 5.4e-29 100.5 0.0 7.5e-17 61.5 0.0 3.7 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 ORY98498.1 - 3.1e-24 85.1 0.0 3.6e-15 56.0 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 ORY98498.1 - 1.1e-19 70.5 0.0 1.1e-07 31.8 0.0 4.1 4 1 0 4 4 4 3 PAS fold PAS_4 PF08448.10 ORY98498.1 - 6.4e-13 48.9 0.0 0.0008 19.6 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ORY98498.1 - 1.2e-09 38.3 0.0 2.7e-08 33.9 0.0 2.5 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.7 ORY98498.1 - 8.3e-05 22.5 0.0 0.049 13.7 0.0 3.1 3 0 0 3 3 3 1 PAS domain PROCN PF08083.11 ORY98499.1 - 1.4e-233 774.9 9.2 1.6e-233 774.7 8.0 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 ORY98499.1 - 4.3e-128 425.7 0.2 7.1e-128 425.0 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 ORY98499.1 - 6.2e-89 295.7 4.0 1.4e-88 294.6 4.0 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 ORY98499.1 - 8.8e-85 282.5 2.1 8.8e-85 282.5 2.1 1.9 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 ORY98499.1 - 1.2e-65 219.6 0.4 1e-53 181.0 0.0 2.5 2 0 0 2 2 2 2 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 ORY98499.1 - 1.7e-48 163.6 0.1 3.7e-48 162.5 0.1 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 ORY98499.1 - 1e-45 154.0 0.4 2.7e-45 152.6 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 ORY98499.1 - 5.1e-15 56.0 0.0 1.8e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Hom_end-associated Hint JAB PF01398.21 ORY98499.1 - 9.3e-08 32.1 0.0 2.1e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Hom_end PF05204.14 ORY98499.1 - 0.00017 21.7 0.0 0.00082 19.5 0.0 2.0 2 0 0 2 2 2 1 Homing endonuclease Hint PF01079.20 ORY98499.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 ORY98499.1 - 0.082 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Hint domain LAGLIDADG_3 PF14528.6 ORY98499.1 - 0.17 12.2 0.1 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 LAGLIDADG-like domain NT-C2 PF10358.9 ORY98500.1 - 2.3e-13 50.1 0.0 2.7e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins NIF PF03031.18 ORY98501.1 - 1.1e-51 174.7 0.3 1.6e-51 174.2 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Med3 PF11593.8 ORY98501.1 - 1.5 7.9 8.9 2.3 7.3 8.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF737 PF05300.11 ORY98501.1 - 7.1 6.9 10.5 14 6.0 10.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF737) EF-hand_7 PF13499.6 ORY98502.1 - 1.6e-24 86.1 1.2 6.4e-17 61.8 0.2 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY98502.1 - 1.2e-21 74.6 10.0 2.2e-06 26.8 0.4 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY98502.1 - 6.5e-20 69.3 8.0 2.8e-06 26.8 0.2 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 ORY98502.1 - 2.3e-15 55.3 7.1 1.8e-05 24.0 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 ORY98502.1 - 4.3e-11 42.5 9.8 0.00075 19.3 0.9 4.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 ORY98502.1 - 1.7e-07 31.1 3.0 0.39 10.7 0.1 3.8 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY98502.1 - 0.00049 20.4 1.9 0.12 12.7 1.8 3.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORY98502.1 - 0.0068 16.7 0.8 1.8 9.0 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain DUF1707 PF08044.11 ORY98502.1 - 0.049 13.7 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) S10_plectin PF03501.15 ORY98502.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain Toprim PF01751.22 ORY98502.1 - 0.15 12.3 0.1 1.8 8.8 0.0 2.4 1 1 1 2 2 2 0 Toprim domain Caleosin PF05042.13 ORY98502.1 - 0.26 11.2 2.9 15 5.5 0.0 3.1 2 1 1 3 3 3 0 Caleosin related protein Ras PF00071.22 ORY98503.1 - 1.6e-55 187.1 0.1 1.9e-55 186.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY98503.1 - 6.8e-20 71.5 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY98503.1 - 3.4e-07 29.9 0.1 4.4e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY98503.1 - 0.00048 19.7 0.3 0.0024 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY98503.1 - 0.0057 16.6 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY98503.1 - 0.056 13.0 0.2 0.29 10.7 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.6 ORY98503.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORY98503.1 - 0.15 12.1 0.2 0.22 11.6 0.2 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PGI PF00342.19 ORY98504.1 - 4.3e-253 840.2 0.1 4.9e-253 840.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CPSase_L_D3 PF02787.19 ORY98504.1 - 0.015 15.6 0.5 0.032 14.6 0.1 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain FliG_C PF01706.16 ORY98504.1 - 0.12 12.5 0.2 11 6.3 0.1 3.1 2 1 1 3 3 3 0 FliG C-terminal domain RRM_1 PF00076.22 ORY98506.1 - 2.5e-09 36.8 0.0 4.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_alpha PF05793.12 ORY98506.1 - 0.00073 18.3 9.7 0.00097 17.8 9.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_bind PF08675.11 ORY98506.1 - 0.0038 17.2 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain Nup35_RRM_2 PF14605.6 ORY98506.1 - 0.0086 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ndc1_Nup PF09531.10 ORY98506.1 - 0.41 9.3 11.5 0.48 9.0 11.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF3_p135 PF12807.7 ORY98506.1 - 2.2 8.3 5.0 3.5 7.6 5.0 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 TFIIA PF03153.13 ORY98506.1 - 8 6.3 30.6 12 5.8 30.3 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 ORY98508.1 - 7.6e-33 113.9 47.4 2e-20 73.0 23.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY98508.1 - 1.3e-08 34.2 16.4 1.3e-08 34.2 16.4 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter Kinocilin PF15033.6 ORY98508.1 - 0.0053 16.4 1.5 0.0095 15.6 0.0 2.2 2 0 0 2 2 2 1 Kinocilin protein Orf78 PF06024.12 ORY98508.1 - 0.31 11.4 2.0 13 6.1 0.0 3.4 3 0 0 3 3 3 0 Orf78 (ac78) DUF5527 PF17665.1 ORY98508.1 - 3.2 7.3 5.5 2.3 7.7 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5527) IGPS PF00218.21 ORY98509.1 - 2.1e-95 318.7 0.3 7.3e-95 317.0 0.1 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 ORY98509.1 - 1.7e-50 171.5 0.1 5.7e-50 169.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.22 ORY98509.1 - 8.4e-48 162.7 0.0 2.2e-40 138.5 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 ORY98509.1 - 1.3e-09 38.1 0.1 3.8e-09 36.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.14 ORY98509.1 - 0.00059 19.1 0.6 0.94 8.6 0.0 3.7 4 0 0 4 4 4 2 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 ORY98509.1 - 0.13 11.7 0.0 0.92 8.9 0.0 2.3 3 0 0 3 3 3 0 Histidine biosynthesis protein NMO PF03060.15 ORY98509.1 - 0.29 10.5 3.4 27 4.0 0.1 3.2 2 1 1 3 3 3 0 Nitronate monooxygenase DUF4588 PF15251.6 ORY98510.1 - 0.0021 17.9 8.2 0.009 15.8 8.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Presenilin PF01080.17 ORY98510.1 - 0.61 8.8 2.8 0.67 8.7 2.8 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 ORY98510.1 - 0.71 8.1 13.8 0.83 7.9 13.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 ORY98510.1 - 1.5 7.6 3.6 1.9 7.2 3.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ANAPC_CDC26 PF10471.9 ORY98510.1 - 1.7 9.5 17.5 1 10.2 13.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 ABC_tran_Xtn PF12848.7 ORY98510.1 - 4.7 7.3 12.2 0.095 12.7 5.3 1.8 2 0 0 2 2 2 0 ABC transporter EF-hand_7 PF13499.6 ORY98511.1 - 4e-06 27.2 0.0 2.8e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY98511.1 - 0.00095 18.9 0.1 0.0034 17.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORY98511.1 - 0.0041 16.5 0.2 0.0089 15.5 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 ORY98511.1 - 0.0048 16.3 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF_assoc_1 PF08355.12 ORY98511.1 - 0.0061 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 EF hand associated ANAPC3 PF12895.7 ORY98511.1 - 0.0077 16.4 2.4 0.041 14.1 0.1 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ORY98511.1 - 0.12 12.6 0.3 0.68 10.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MRP-S25 PF13741.6 ORY98512.1 - 2.4e-42 145.1 3.5 3.2e-42 144.7 3.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 ORY98512.1 - 7.6e-05 23.0 1.7 0.0026 18.0 1.8 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Tn7_Tnp_TnsA_N PF08722.11 ORY98512.1 - 0.0087 16.2 2.0 0.009 16.2 0.5 1.7 2 0 0 2 2 2 1 TnsA endonuclease N terminal HTH_12 PF08461.10 ORY98512.1 - 0.082 12.9 0.0 0.082 12.9 0.0 2.3 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain DUF4381 PF14316.6 ORY98513.1 - 0.0055 17.0 2.5 0.041 14.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) DUF1980 PF09323.10 ORY98513.1 - 0.19 11.6 1.5 0.32 10.9 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Aminotran_3 PF00202.21 ORY98514.1 - 2.3e-46 158.3 0.0 1e-24 87.0 0.0 3.4 2 2 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 ORY98514.1 - 2.2e-05 24.4 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain BATS PF06968.13 ORY98515.1 - 4e-20 71.8 0.2 1.1e-19 70.4 0.1 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ORY98515.1 - 4.2e-15 56.5 0.1 5.9e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF1394 PF07159.12 ORY98516.1 - 1.3e-103 346.5 0.0 1.5e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) PQ-loop PF04193.14 ORY98517.1 - 2.2e-32 110.6 13.6 1.1e-16 60.3 3.2 3.1 3 0 0 3 3 3 2 PQ loop repeat Adipogenin PF15202.6 ORY98517.1 - 5.7 7.0 10.0 0.31 11.1 0.3 3.3 4 0 0 4 4 4 0 Adipogenin PI3_PI4_kinase PF00454.27 ORY98518.1 - 2.8e-52 178.0 0.0 5.8e-52 177.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ORY98518.1 - 6.4e-26 91.4 10.9 1.5e-23 83.6 7.0 3.0 2 1 0 2 2 2 1 FAT domain UME PF08064.13 ORY98518.1 - 5.3e-12 45.5 0.9 4.2e-09 36.2 0.0 3.6 2 1 1 3 3 3 2 UME (NUC010) domain FATC PF02260.20 ORY98518.1 - 6.2e-11 41.9 0.1 6.2e-09 35.5 0.0 2.6 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 ORY98518.1 - 0.0056 16.6 3.3 0.0082 16.1 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3385) Utp12 PF04003.12 ORY98518.1 - 0.56 10.5 2.6 4.2 7.7 0.0 3.7 3 0 0 3 3 3 0 Dip2/Utp12 Family SNARE_assoc PF09335.11 ORY98519.1 - 1.9e-22 80.0 5.3 1.9e-22 80.0 5.3 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF21 PF01595.20 ORY98519.1 - 0.32 10.7 4.5 0.74 9.5 2.4 2.5 2 1 1 3 3 3 0 Cyclin M transmembrane N-terminal domain DUF2070 PF09843.9 ORY98519.1 - 0.97 7.6 6.3 1.6 7.0 6.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tau95 PF09734.9 ORY98520.1 - 9e-30 104.3 3.2 9.6e-30 104.2 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 ORY98520.1 - 1.9e-24 86.3 0.0 1.9e-24 86.3 0.0 3.8 3 1 0 3 3 1 1 Tau95 Triple barrel domain Borrelia_P83 PF05262.11 ORY98520.1 - 0.0071 14.9 5.7 0.01 14.4 5.7 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein RNA_pol_Rpc4 PF05132.14 ORY98520.1 - 0.014 15.8 2.9 0.014 15.8 2.9 1.9 2 0 0 2 2 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 ORY98520.1 - 0.017 15.4 11.3 0.017 15.4 11.3 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RP-C_C PF11800.8 ORY98520.1 - 0.057 13.5 7.7 0.11 12.6 7.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 ORY98520.1 - 0.067 12.0 5.6 0.094 11.5 5.6 1.2 1 0 0 1 1 1 0 Presenilin FemAB PF02388.16 ORY98520.1 - 0.27 10.1 5.8 0.46 9.3 5.8 1.3 1 0 0 1 1 1 0 FemAB family V_ATPase_I PF01496.19 ORY98520.1 - 0.31 8.9 3.4 0.49 8.3 3.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4175 PF13779.6 ORY98520.1 - 0.42 8.5 15.8 0.63 7.9 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.16 ORY98520.1 - 0.48 10.4 1.2 0.78 9.8 1.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BUD22 PF09073.10 ORY98520.1 - 0.62 9.3 17.7 1 8.6 17.7 1.3 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 ORY98520.1 - 0.91 9.6 12.1 3.8 7.6 12.1 1.9 1 1 0 1 1 1 0 DDHD domain Folliculin PF11704.8 ORY98520.1 - 0.97 9.3 4.8 1.8 8.4 4.8 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4446 PF14584.6 ORY98520.1 - 1.4 8.9 4.9 25 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) SLC12 PF03522.15 ORY98520.1 - 1.4 7.8 6.0 2.3 7.1 6.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 ORY98520.1 - 1.6 7.6 7.1 2.7 6.9 7.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ALMT PF11744.8 ORY98520.1 - 1.7 7.4 3.3 2.5 6.8 3.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 ORY98520.1 - 1.8 6.6 4.6 2.3 6.2 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 ORY98520.1 - 3 6.5 8.0 5.7 5.6 8.0 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4407 PF14362.6 ORY98520.1 - 3.1 7.1 7.2 5.2 6.3 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMU163 PF17119.5 ORY98520.1 - 3.6 6.7 6.7 6.1 5.9 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Coilin_N PF15862.5 ORY98520.1 - 3.9 7.3 12.0 0.22 11.3 6.1 1.9 2 0 0 2 2 2 0 Coilin N-terminus Zip PF02535.22 ORY98520.1 - 6.6 5.9 4.3 9.9 5.3 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LMWPc PF01451.21 ORY98521.1 - 2.6e-35 121.9 0.0 2.9e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MMR_HSR1_Xtn PF16897.5 ORY98523.1 - 1.8e-42 143.6 3.2 1.8e-42 143.6 3.2 1.6 2 0 0 2 2 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 ORY98523.1 - 2e-22 79.0 0.1 3.7e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 ORY98523.1 - 1.5e-19 70.1 0.0 3.5e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY98523.1 - 7.4e-10 38.6 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY98523.1 - 0.00091 19.3 0.1 0.13 12.3 0.0 2.5 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 ORY98523.1 - 0.0013 18.7 1.2 0.018 14.9 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase Arf PF00025.21 ORY98523.1 - 0.005 16.3 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family AIG1 PF04548.16 ORY98523.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 ORY98523.1 - 0.026 14.8 0.3 0.72 10.1 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY98523.1 - 0.028 13.9 0.0 0.066 12.6 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Csm2_III-A PF03750.13 ORY98523.1 - 0.036 14.9 0.4 0.37 11.6 0.1 2.3 2 0 0 2 2 2 0 Csm2 Type III-A AAA_28 PF13521.6 ORY98523.1 - 0.038 14.2 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ORY98523.1 - 0.042 12.8 0.0 0.082 11.9 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 ORY98523.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DinI PF06183.13 ORY98523.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 DinI-like family AAA_25 PF13481.6 ORY98524.1 - 2.1e-24 86.2 0.0 3.7e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 ORY98524.1 - 2.2e-10 40.3 0.0 4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 ORY98524.1 - 7.2e-08 32.8 0.0 2.7e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY98524.1 - 2.6e-05 24.7 0.0 8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 ORY98524.1 - 5.1e-05 22.7 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_29 PF13555.6 ORY98524.1 - 0.002 17.8 0.1 0.0052 16.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Toprim_2 PF13155.6 ORY98524.1 - 0.0026 18.1 0.0 0.0094 16.4 0.0 1.9 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.6 ORY98524.1 - 0.0028 18.0 0.0 0.21 12.0 0.0 2.7 2 1 0 2 2 2 1 Toprim domain ABC_tran PF00005.27 ORY98524.1 - 0.0057 17.2 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Toprim_4 PF13662.6 ORY98524.1 - 0.0074 16.7 0.0 0.22 12.0 0.0 2.6 2 0 0 2 2 2 1 Toprim domain AAA_23 PF13476.6 ORY98524.1 - 0.008 16.7 0.2 0.008 16.7 0.2 2.2 3 0 0 3 3 1 1 AAA domain IstB_IS21 PF01695.17 ORY98524.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 ORY98524.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 ORY98524.1 - 0.028 14.7 0.0 0.082 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.7 ORY98524.1 - 0.037 14.0 1.0 0.095 12.7 1.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_18 PF13238.6 ORY98524.1 - 0.044 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY98524.1 - 0.052 13.1 0.2 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 ORY98524.1 - 0.073 12.9 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 ORY98524.1 - 0.088 12.7 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 ORY98524.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY98524.1 - 0.12 12.6 0.1 0.72 10.0 0.0 2.5 2 1 0 2 2 1 0 AAA domain Toprim PF01751.22 ORY98524.1 - 0.15 12.3 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 Toprim domain DUF2188 PF09954.9 ORY98524.1 - 0.17 12.0 0.3 4.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Med14 PF08638.11 ORY98525.1 - 1.3e-61 207.4 0.9 3.5e-61 206.0 0.7 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 COBRA1 PF06209.13 ORY98525.1 - 0.0057 15.6 0.4 0.011 14.6 0.4 1.4 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Cdh1_DBD_1 PF18196.1 ORY98525.1 - 0.45 10.9 2.2 2.6 8.4 0.8 2.4 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 FAR1 PF03101.15 ORY98526.1 - 0.00011 22.9 0.5 0.00011 22.9 0.5 2.4 2 0 0 2 2 2 1 FAR1 DNA-binding domain Aminotran_1_2 PF00155.21 ORY98527.1 - 1.7e-39 136.1 0.0 1.9e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Mito_carr PF00153.27 ORY98528.1 - 1.2e-57 191.8 3.4 2e-21 75.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 ORY98528.1 - 0.024 14.9 0.1 33 4.8 0.0 3.4 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase MazG-like PF12643.7 ORY98528.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 MazG-like family Trm112p PF03966.16 ORY98529.1 - 8.2e-17 61.6 0.1 1.1e-16 61.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein PhnA_Zn_Ribbon PF08274.12 ORY98529.1 - 0.0078 16.2 0.2 0.0078 16.2 0.2 1.8 2 0 0 2 2 2 1 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 ORY98529.1 - 0.063 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-UDP PF14569.6 ORY98529.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-NADH-PPase PF09297.11 ORY98529.1 - 0.39 10.4 0.3 0.39 10.4 0.3 1.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HMG_box PF00505.19 ORY98530.1 - 5e-19 68.5 3.5 5e-19 68.5 3.5 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY98530.1 - 2.9e-09 37.4 2.4 5.5e-09 36.5 2.4 1.4 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 ORY98530.1 - 0.026 14.7 1.1 0.036 14.2 1.1 1.3 1 0 0 1 1 1 0 Protamine and protamine like YABBY PF04690.13 ORY98530.1 - 0.53 10.8 4.1 0.28 11.7 1.7 1.7 1 1 0 2 2 2 0 YABBY protein Methyltransf_11 PF08241.12 ORY98532.1 - 8.6e-08 32.7 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY98532.1 - 1.8e-06 28.5 0.0 4.6e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY98532.1 - 0.0013 18.6 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY98532.1 - 0.0057 17.4 0.0 0.015 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY98532.1 - 0.017 14.4 0.0 0.086 12.2 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY98532.1 - 0.04 13.7 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EF_assoc_2 PF08356.12 ORY98533.1 - 3.9e-36 122.9 0.0 1.6e-35 121.0 0.0 2.1 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 ORY98533.1 - 9.8e-30 102.0 2.5 2.1e-29 100.9 2.5 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 ORY98533.1 - 6.8e-21 74.5 0.0 3.9e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY98533.1 - 6.8e-10 39.2 0.0 0.00048 20.3 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 ORY98533.1 - 2e-08 33.2 2.5 0.00076 18.9 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY98533.1 - 4e-08 32.6 0.6 0.0032 17.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORY98533.1 - 1.2e-07 32.1 0.3 0.031 14.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY98533.1 - 5.6e-06 25.6 5.0 0.00023 20.5 0.7 2.6 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 ORY98533.1 - 4.6e-05 23.2 3.8 0.029 14.2 0.3 2.5 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 ORY98533.1 - 0.00017 21.6 0.0 0.0005 20.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SPARC_Ca_bdg PF10591.9 ORY98533.1 - 0.0056 17.0 0.9 1.5 9.2 0.2 2.8 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region AAA_22 PF13401.6 ORY98533.1 - 0.0064 16.8 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY98533.1 - 0.0088 16.3 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORY98533.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) EF-hand_8 PF13833.6 ORY98533.1 - 0.013 15.4 1.5 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair Viral_helicase1 PF01443.18 ORY98533.1 - 0.02 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 ORY98533.1 - 0.043 14.2 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 ORY98533.1 - 0.06 12.9 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORY98533.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 ORY98533.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ploopntkinase3 PF18751.1 ORY98533.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 eIF-3c_N PF05470.12 ORY98534.1 - 0.0048 15.3 0.4 0.0068 14.8 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ribosomal_L35p PF01632.19 ORY98535.1 - 1.5e-16 60.6 3.2 1.8e-16 60.4 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 zf-C4H2 PF10146.9 ORY98536.1 - 6.4e-10 39.7 10.0 7.8e-10 39.4 10.0 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein KASH_CCD PF14662.6 ORY98536.1 - 0.0028 17.5 15.0 0.0097 15.7 5.0 2.3 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH eIF3_N PF09440.10 ORY98536.1 - 0.012 16.1 7.1 0.012 16.1 7.1 1.9 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF5089 PF17002.5 ORY98536.1 - 0.018 14.9 4.6 0.023 14.6 4.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) Bul1_C PF04426.12 ORY98536.1 - 0.035 13.5 6.8 0.06 12.8 6.8 1.4 1 1 0 1 1 1 0 Bul1 C terminus EzrA PF06160.12 ORY98536.1 - 0.036 12.2 8.7 0.045 11.9 8.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 ORY98536.1 - 0.038 14.4 11.1 0.049 14.1 11.1 1.1 1 0 0 1 1 1 0 Fez1 SRP1_TIP1 PF00660.17 ORY98536.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Seripauperin and TIP1 family SKA2 PF16740.5 ORY98536.1 - 0.11 12.3 16.5 0.23 11.2 4.9 3.2 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 BLI1 PF17324.2 ORY98536.1 - 0.24 12.1 6.3 5.3 7.8 1.8 2.3 1 1 1 2 2 2 0 BLOC-1 interactor 1 kleA_kleC PF17383.2 ORY98536.1 - 0.24 11.8 7.0 2.9 8.3 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A DUF1664 PF07889.12 ORY98536.1 - 0.29 11.2 9.4 0.25 11.4 5.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 ORY98536.1 - 0.42 10.7 18.4 0.12 12.4 6.7 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain OmpH PF03938.14 ORY98536.1 - 0.74 10.1 14.6 0.038 14.3 7.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 ORY98536.1 - 1.4 8.9 6.3 1.2 9.2 3.9 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF349 PF03993.12 ORY98536.1 - 2 8.8 6.1 6.6 7.1 3.2 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Prominin PF05478.11 ORY98536.1 - 2.2 6.1 6.9 2.2 6.1 6.0 1.3 1 1 0 1 1 1 0 Prominin DUF948 PF06103.11 ORY98536.1 - 3 8.2 6.0 3.7 7.9 1.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.18 ORY98536.1 - 3.2 8.0 11.0 5.4 7.3 1.2 3.2 1 1 2 3 3 3 0 Homeobox associated leucine zipper FUSC PF04632.12 ORY98536.1 - 5.1 5.5 8.7 6.1 5.3 8.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 ORY98536.1 - 7.5 5.3 7.2 8.5 5.2 7.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Methyltransf_25 PF13649.6 ORY98538.1 - 1.3e-07 32.2 0.0 4.2e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY98538.1 - 1.3e-05 25.7 0.0 2.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY98538.1 - 0.0063 17.2 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY98538.1 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY98538.1 - 0.018 14.5 0.0 0.081 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Fer2_BFD PF04324.15 ORY98538.1 - 0.15 12.4 0.5 0.28 11.6 0.5 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain SHQ1 PF04925.15 ORY98539.1 - 7.9e-67 224.2 4.9 1.1e-66 223.7 4.9 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 ORY98539.1 - 0.013 15.9 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 PIH1 CS-like domain Pkinase PF00069.25 ORY98541.1 - 2.3e-45 155.0 0.0 3.5e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98541.1 - 9.6e-23 80.8 0.0 1.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98541.1 - 0.0021 17.5 2.3 0.0042 16.5 0.2 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORY98541.1 - 0.0041 17.1 0.1 0.91 9.4 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF4364 PF14277.6 ORY98541.1 - 0.033 13.9 0.4 0.05 13.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) FTA2 PF13095.6 ORY98541.1 - 0.062 12.9 0.4 0.8 9.3 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORY98541.1 - 0.79 8.4 3.9 2.9 6.6 3.9 2.0 1 1 0 1 1 1 0 Fungal protein kinase MRP-S34 PF16053.5 ORY98542.1 - 5.1e-11 42.3 0.1 6e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 LEA_2 PF03168.13 ORY98543.1 - 2.7e-05 24.7 0.1 4.6e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein MBOAT_2 PF13813.6 ORY98544.1 - 4.5e-19 68.5 3.4 1.1e-18 67.2 3.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DFRP_C PF16543.5 ORY98545.1 - 5.8e-28 97.2 2.0 5.8e-28 97.2 2.0 3.1 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 ORY98545.1 - 1.3e-06 28.2 1.8 1.3e-06 28.2 1.8 2.9 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY98545.1 - 2e-06 27.5 9.6 0.00012 21.8 1.9 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 ORY98545.1 - 6.2e-06 26.9 18.5 0.0034 18.1 8.6 4.0 2 1 1 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 ORY98545.1 - 6.7e-05 22.8 7.6 6.7e-05 22.8 7.6 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_2 PF14608.6 ORY98545.1 - 0.046 14.2 3.4 0.046 14.2 3.4 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 ORY98545.1 - 3.1 8.0 6.9 1.6 8.9 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger containing family DSPc PF00782.20 ORY98546.1 - 2.1e-14 53.5 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY98546.1 - 3.3e-05 24.0 0.0 0.00014 22.0 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.12 ORY98546.1 - 4.8e-05 23.1 0.0 0.00012 21.8 0.0 1.7 1 1 1 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 ORY98546.1 - 0.0033 17.0 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Chromo PF00385.24 ORY98547.1 - 9.9e-14 51.0 0.5 9.9e-14 51.0 0.5 3.3 3 1 1 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 ORY98547.1 - 5.2e-08 32.9 0.0 5.2e-08 32.9 0.0 2.3 3 0 0 3 3 3 1 Chromo shadow domain AT_hook PF02178.19 ORY98547.1 - 0.098 12.6 1.4 0.3 11.1 1.4 1.9 1 0 0 1 1 1 0 AT hook motif HSP33 PF01430.19 ORY98549.1 - 0.0035 16.8 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein Tetraspanin PF00335.20 ORY98549.1 - 0.0036 17.1 3.9 0.0052 16.5 3.9 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4199 PF13858.6 ORY98549.1 - 0.0052 17.2 2.1 0.0069 16.8 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DUF4389 PF14333.6 ORY98549.1 - 0.024 14.6 2.1 0.26 11.2 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF4381 PF14316.6 ORY98549.1 - 0.053 13.8 0.2 0.23 11.7 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) CcmH PF03918.14 ORY98549.1 - 0.092 12.0 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein SieB PF14163.6 ORY98549.1 - 0.16 11.5 1.2 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B Viral_Beta_CD PF04530.12 ORY98549.1 - 0.19 12.0 2.0 0.2 11.9 0.7 1.6 1 1 1 2 2 2 0 Viral Beta C/D like family LRR19-TM PF15176.6 ORY98549.1 - 0.29 11.2 2.7 12 5.9 0.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Orf78 PF06024.12 ORY98549.1 - 7.6 6.9 6.1 5.9 7.2 4.4 1.7 1 1 1 2 2 2 0 Orf78 (ac78) Ribosomal_L27e PF01777.18 ORY98550.1 - 5.8e-37 125.9 7.6 5.8e-37 125.9 7.6 1.4 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 ORY98550.1 - 0.0013 18.7 5.3 0.0024 17.8 5.3 1.6 1 1 0 1 1 1 1 KOW motif Sec16 PF12932.7 ORY98550.1 - 0.033 14.8 0.1 0.044 14.4 0.1 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region F-box-like PF12937.7 ORY98551.1 - 3.5e-08 33.2 1.3 1.3e-07 31.4 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY98551.1 - 1.5e-06 27.9 1.6 1.2e-05 25.1 0.1 2.4 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 ORY98552.1 - 0.012 15.6 4.1 0.14 12.3 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat PAP2 PF01569.21 ORY98553.1 - 2.5e-31 108.2 3.0 3e-30 104.7 0.7 2.4 1 1 1 2 2 2 2 PAP2 superfamily OFeT_1 PF16955.5 ORY98553.1 - 0.0051 16.5 0.2 0.0081 15.9 0.2 1.2 1 0 0 1 1 1 1 Ferrous iron uptake permease, iron-lead transporter TPPK_C PF12555.8 ORY98553.1 - 0.013 15.5 1.3 0.17 12.0 2.6 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal YhhN PF07947.14 ORY98553.1 - 0.27 10.8 6.4 0.058 13.0 0.6 2.3 2 0 0 2 2 2 0 YhhN family TMEM18 PF14770.6 ORY98553.1 - 0.47 10.4 3.4 14 5.7 0.0 2.7 2 1 1 3 3 3 0 Transmembrane protein 18 ADK PF00406.22 ORY98554.1 - 2.9e-48 163.8 0.0 3.7e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY98554.1 - 7.7e-22 78.2 0.0 1.9e-21 76.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 ORY98554.1 - 2.6e-12 46.5 0.0 5.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 ORY98554.1 - 2.4e-06 27.7 0.1 0.00054 20.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 ORY98554.1 - 2.5e-05 24.8 0.0 5.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY98554.1 - 0.049 12.9 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin SAP18 PF06487.12 ORY98555.1 - 4.8e-36 124.0 0.0 7.6e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Hexokinase_2 PF03727.16 ORY98556.1 - 9.4e-68 228.2 0.0 1.2e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY98556.1 - 1.8e-46 158.5 0.0 2.9e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase HATPase_c PF02518.26 ORY98557.1 - 4.5e-28 98.0 0.0 1.2e-27 96.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY98557.1 - 5.2e-23 81.4 0.0 6.1e-22 77.9 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain Pkinase_Tyr PF07714.17 ORY98557.1 - 1.3e-12 47.6 0.0 6.1e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase HisKA PF00512.25 ORY98557.1 - 6.6e-11 42.1 0.9 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 ORY98557.1 - 1.4e-08 34.5 0.0 3.2e-07 30.0 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Ephrin_rec_like PF07699.13 ORY98557.1 - 0.01 15.6 4.4 0.01 15.6 4.4 3.0 2 1 1 3 3 3 0 Putative ephrin-receptor like HATPase_c_3 PF13589.6 ORY98557.1 - 0.021 14.7 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NCD3G PF07562.14 ORY98557.1 - 0.046 13.7 8.5 0.3 11.1 1.7 2.8 1 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Helo_like_N PF17111.5 ORY98557.1 - 0.089 12.1 1.9 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins TNFR_c6 PF00020.18 ORY98557.1 - 8.9 6.8 15.0 6.9 7.2 3.7 3.3 2 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region Peripla_BP_4 PF13407.6 ORY98558.1 - 1.4e-09 37.9 0.0 1.2e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain Kinesin PF00225.23 ORY98559.1 - 6.1e-96 321.2 0.2 1.7e-95 319.7 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY98559.1 - 3.5e-18 66.0 0.0 9.5e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DPPIV_rep PF18811.1 ORY98559.1 - 4.2 7.4 5.5 13 5.9 0.1 3.7 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Peptidase_S24 PF00717.23 ORY98560.1 - 1.9e-07 30.9 0.1 4.8e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ORY98560.1 - 0.082 12.7 0.0 2.7 7.8 0.0 2.3 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 LRR_8 PF13855.6 ORY98561.1 - 3.2e-19 68.4 20.7 2.4e-11 43.2 3.4 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY98561.1 - 7.8e-14 51.6 9.8 7e-07 29.5 0.7 4.4 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY98561.1 - 1.5e-05 24.6 10.5 0.28 11.4 0.4 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 ORY98561.1 - 4.2e-05 23.5 10.7 1 10.2 0.1 6.6 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_9 PF14580.6 ORY98561.1 - 0.00041 19.9 2.3 0.85 9.1 0.5 3.3 2 1 0 3 3 3 2 Leucine-rich repeat DUF1118 PF06549.12 ORY98561.1 - 0.042 14.2 3.6 0.14 12.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1118) VIT1 PF01988.19 ORY98563.1 - 3.7e-73 246.0 0.0 4.2e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 VIT family Clr2_transil PF16761.5 ORY98564.1 - 0.027 15.3 0.0 0.071 13.9 0.0 1.7 1 0 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 CTK3 PF12243.8 ORY98565.1 - 2.9e-31 108.1 0.1 5.5e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 ORY98565.1 - 5.1e-17 61.8 7.3 1.7e-16 60.1 7.3 1.9 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTD_bind PF04818.13 ORY98565.1 - 0.0058 17.4 0.0 0.014 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. NDUFB11 PF17250.2 ORY98565.1 - 0.067 13.8 1.9 0.15 12.7 0.6 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit DUF4570 PF15134.6 ORY98566.1 - 4.4 7.4 7.3 4.9 7.2 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) OAD_gamma PF04277.13 ORY98567.1 - 0.059 14.0 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain IMUP PF15761.5 ORY98568.1 - 0.39 11.4 8.4 0.63 10.8 8.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein RAP1 PF07218.11 ORY98568.1 - 7.7 4.6 7.5 9.6 4.3 7.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) tRNA-synt_2 PF00152.20 ORY98569.1 - 1e-73 248.2 0.0 1.3e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY98569.1 - 3.6e-09 36.5 0.7 8.1e-09 35.3 0.7 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY98569.1 - 2.4e-06 27.3 0.0 0.0096 15.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) E1_FCCH PF16190.5 ORY98569.1 - 0.05 13.8 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain RSB_motif PF16294.5 ORY98570.1 - 6.8e-10 39.1 0.2 6.8e-10 39.1 0.2 2.3 2 0 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 ORY98570.1 - 0.00072 19.3 0.1 0.0031 17.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY98570.1 - 0.002 17.9 0.0 0.15 12.0 0.0 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif RL PF17797.1 ORY98570.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RL domain SHMT PF00464.19 ORY98571.1 - 3.8e-202 671.2 0.0 4.6e-202 670.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 ORY98571.1 - 0.0011 18.2 0.0 0.0038 16.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Peptidase_S9 PF00326.21 ORY98572.1 - 1.9e-07 30.8 0.1 6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY98572.1 - 0.00019 20.8 0.2 0.0083 15.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY98572.1 - 0.0019 18.1 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 ORY98572.1 - 0.005 16.4 0.0 0.091 12.3 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 ORY98572.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 ORY98572.1 - 0.055 13.0 0.0 0.94 9.0 0.0 2.1 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Ins134_P3_kin PF05770.11 ORY98573.1 - 2.9e-31 108.5 0.0 3.4e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain DUF2789 PF10982.8 ORY98574.1 - 0.0023 18.0 0.1 0.0051 16.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2789) Myb_DNA-binding PF00249.31 ORY98574.1 - 0.0042 17.3 0.1 0.081 13.1 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain RRP36 PF06102.12 ORY98574.1 - 0.025 14.6 0.6 0.044 13.7 0.6 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 NMD3 PF04981.13 ORY98574.1 - 0.029 13.8 5.2 0.027 13.9 3.4 1.7 2 0 0 2 2 2 0 NMD3 family Myb_DNA-bind_6 PF13921.6 ORY98574.1 - 0.064 13.5 0.9 0.064 13.5 0.9 2.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain Cytochrome_C7 PF14522.6 ORY98574.1 - 0.47 10.5 15.0 0.88 9.6 0.8 2.6 1 1 2 3 3 3 0 Cytochrome c7 and related cytochrome c OPT PF03169.15 ORY98576.1 - 3.6e-186 620.5 53.1 4.1e-186 620.3 53.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3169 PF11368.8 ORY98576.1 - 0.45 10.0 8.1 0.12 11.9 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) TraQ PF09679.10 ORY98576.1 - 2.1 8.3 4.4 5.6 7.0 4.4 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Pkinase PF00069.25 ORY98577.1 - 2.2e-70 237.0 0.0 2.7e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98577.1 - 1.2e-52 178.7 0.0 1.6e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98577.1 - 4.5e-05 22.9 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 ORY98577.1 - 0.0054 16.4 0.0 0.037 13.6 0.0 1.9 1 1 1 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 ORY98577.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 ORY98577.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CH PF00307.31 ORY98578.1 - 0.01 16.0 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain Claudin_2 PF13903.6 ORY98579.1 - 0.03 14.1 0.4 0.033 13.9 0.4 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Paf67 PF10255.9 ORY98580.1 - 3.2e-171 569.8 4.7 4.2e-171 569.4 4.7 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 ORY98580.1 - 0.00069 19.5 0.0 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY98580.1 - 0.0023 17.7 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY98580.1 - 0.034 14.4 0.0 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fra10Ac1 PF09725.9 ORY98581.1 - 1.4e-48 164.1 0.9 1.4e-48 164.1 0.9 1.7 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 SelP_N PF04592.14 ORY98581.1 - 0.0028 17.1 5.0 0.0028 17.1 5.0 1.4 2 0 0 2 2 2 1 Selenoprotein P, N terminal region DUF2197 PF09963.9 ORY98581.1 - 0.029 14.6 0.7 0.077 13.3 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) RR_TM4-6 PF06459.12 ORY98581.1 - 1.6 8.5 11.5 2.1 8.1 11.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 ORY98581.1 - 2.5 7.2 12.0 3.5 6.7 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDC45 PF02724.14 ORY98581.1 - 6.5 4.9 12.2 8.3 4.6 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Med4 PF10018.9 ORY98582.1 - 6.1e-05 22.8 0.7 6.9e-05 22.6 0.7 1.0 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4962 PF16332.5 ORY98582.1 - 0.091 11.2 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Exo_endo_phos PF03372.23 ORY98583.1 - 2.7e-18 66.3 0.3 4e-18 65.8 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_holin_3_6 PF07332.11 ORY98583.1 - 0.011 15.8 8.7 0.017 15.2 8.7 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Tetraspanin PF00335.20 ORY98583.1 - 0.39 10.4 4.1 0.64 9.7 4.1 1.3 1 0 0 1 1 1 0 Tetraspanin family ABC2_membrane_3 PF12698.7 ORY98583.1 - 5.2 6.1 8.8 7.9 5.5 8.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Mon2_C PF16206.5 ORY98584.1 - 4.9e-86 289.6 2.3 5.3e-55 186.9 1.9 3.0 1 1 1 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 ORY98584.1 - 2.6e-56 190.1 3.9 6.3e-56 188.8 3.9 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 ORY98584.1 - 1.5e-53 180.9 1.9 1.5e-51 174.4 0.5 4.1 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY98584.1 - 5.3e-05 23.0 0.1 0.0037 17.1 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) SCP2 PF02036.17 ORY98585.1 - 1.6e-24 86.3 1.4 2e-24 86.0 1.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ORY98585.1 - 0.00023 21.4 0.2 0.00033 20.9 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF3700 PF12481.8 ORY98585.1 - 0.039 13.4 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Aluminium induced protein NUDIX PF00293.28 ORY98586.1 - 1.4e-21 76.9 0.3 1.7e-21 76.7 0.3 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ORY98586.1 - 0.00011 22.2 0.3 0.0002 21.3 0.3 1.4 1 1 0 1 1 1 1 NUDIX domain Glyco_transf_8 PF01501.20 ORY98587.1 - 2.1e-18 66.8 0.0 3.3e-09 36.7 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ORY98587.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative HSP70 PF00012.20 ORY98588.1 - 5e-83 279.3 13.8 5e-83 279.3 13.8 2.7 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORY98588.1 - 9.6e-05 21.3 0.3 0.00048 19.0 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein zf-C2H2 PF00096.26 ORY98589.1 - 5.7e-16 58.0 21.5 6.2e-07 29.5 2.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY98589.1 - 1.4e-12 47.4 17.4 2e-07 31.1 2.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY98589.1 - 9.6e-11 41.6 17.0 0.0038 17.9 1.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY98589.1 - 9.7e-11 41.4 7.9 0.00023 21.1 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY98589.1 - 1.2e-07 31.8 5.3 0.0098 16.2 0.0 3.7 3 1 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY98589.1 - 9.1e-05 22.7 6.3 0.0076 16.6 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORY98589.1 - 0.0024 18.3 4.9 0.03 14.8 0.4 2.6 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 ORY98589.1 - 0.0091 16.1 3.3 2.9 8.1 0.1 3.3 2 1 1 3 3 3 1 Zic proteins zinc finger domain LIM PF00412.22 ORY98589.1 - 0.02 15.1 2.1 0.02 15.1 2.1 2.0 1 1 0 2 2 2 0 LIM domain zf-C2H2_8 PF15909.5 ORY98589.1 - 0.021 15.1 8.1 0.29 11.4 4.8 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 ORY98589.1 - 0.025 14.5 13.1 0.62 10.0 3.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORY98589.1 - 0.043 13.6 10.9 2.1 8.2 0.4 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 ORY98589.1 - 0.082 12.5 4.0 6.8 6.4 0.4 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 ORY98589.1 - 0.16 12.1 4.2 3.8 7.7 0.9 2.7 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_aberr PF17017.5 ORY98589.1 - 0.29 11.3 1.6 0.71 10.0 0.0 2.3 3 0 0 3 3 3 0 Aberrant zinc-finger IBR PF01485.21 ORY98589.1 - 0.31 11.3 9.8 4.8 7.5 9.8 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 ORY98589.1 - 2.1 8.7 5.2 21 5.4 4.9 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zf-LYAR PF08790.11 ORY98589.1 - 2.2 8.2 6.7 2.5 8.1 0.2 3.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 ORY98589.1 - 4.2 7.5 10.2 3.4 7.7 0.8 3.3 3 0 0 3 3 3 0 BED zinc finger zf-AN1 PF01428.16 ORY98589.1 - 4.3 7.6 14.3 27 5.0 1.7 3.1 1 1 1 2 2 2 0 AN1-like Zinc finger AI-2E_transport PF01594.16 ORY98590.1 - 0.16 11.1 1.9 0.19 10.8 1.9 1.0 1 0 0 1 1 1 0 AI-2E family transporter Snf7 PF03357.21 ORY98591.1 - 1.6e-40 138.5 16.6 1.9e-40 138.3 16.6 1.1 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.9 ORY98591.1 - 0.015 15.0 0.6 0.03 14.1 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2520) DUF272 PF03312.15 ORY98591.1 - 0.088 13.1 0.1 0.53 10.5 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF272) Translin PF01997.16 ORY98592.1 - 1.9e-61 207.6 0.1 2.3e-61 207.4 0.1 1.1 1 0 0 1 1 1 1 Translin family Hemocyanin_N PF03722.14 ORY98592.1 - 0.006 17.1 0.2 0.018 15.6 0.2 1.8 1 0 0 1 1 1 1 Hemocyanin, all-alpha domain Isochorismatase PF00857.20 ORY98593.1 - 3.1e-32 112.1 0.1 3.7e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF1501 PF07394.12 ORY98594.1 - 1.7 7.6 8.9 3.7 6.5 8.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Tup_N PF08581.10 ORY98594.1 - 6.4 7.2 16.8 0.095 13.0 1.8 3.5 2 1 1 3 3 3 0 Tup N-terminal DUF3460 PF11943.8 ORY98594.1 - 9.3 6.6 12.9 1.5 9.1 1.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3460) SOG2 PF10428.9 ORY98595.1 - 9 5.4 16.8 11 5.1 16.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cyclin_N PF00134.23 ORY98596.1 - 8.6e-13 48.2 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY98596.1 - 5.5e-06 26.8 0.0 6.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin SET PF00856.28 ORY98597.1 - 1e-21 78.1 0.0 2.4e-21 76.9 0.0 1.7 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 ORY98597.1 - 3.9e-12 47.0 0.0 1.3e-11 45.3 0.0 1.9 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding BSP_II PF05432.11 ORY98597.1 - 0.035 13.8 4.1 0.053 13.2 4.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM91_C PF14648.6 ORY98597.1 - 0.19 10.6 0.7 1.4 7.7 0.3 2.1 1 1 1 2 2 2 0 FAM91 C-terminus CENP-B_dimeris PF09026.10 ORY98597.1 - 0.25 11.8 6.4 0.54 10.7 6.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PseudoU_synth_1 PF01416.20 ORY98598.1 - 5.5e-31 107.2 0.0 8e-29 100.3 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase MBOAT_2 PF13813.6 ORY98599.1 - 2.5e-11 43.7 5.4 2.5e-11 43.7 5.4 2.9 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family PH PF00169.29 ORY98601.1 - 5.5e-07 30.1 0.0 2.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 PH domain DUF5098 PF17023.5 ORY98601.1 - 0.004 16.2 0.1 0.078 11.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5098) Vac_Fusion PF02346.16 ORY98601.1 - 0.0074 15.9 0.2 0.02 14.5 0.2 1.7 1 0 0 1 1 1 1 Chordopoxvirus multifunctional envelope protein A27 Glyco_hydro_28 PF00295.17 ORY98602.1 - 2.1e-59 201.2 16.6 2.8e-59 200.8 16.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 ORY98602.1 - 5.6e-06 26.3 10.0 5.6e-06 26.3 10.0 2.4 2 1 1 3 3 3 1 Right handed beta helix region Actin PF00022.19 ORY98602.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Actin ADK PF00406.22 ORY98603.1 - 5e-13 49.4 1.5 1.2e-11 45.0 1.5 2.9 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY98603.1 - 1e-05 26.0 0.0 4.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY98603.1 - 0.06 13.9 0.1 0.43 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 ORY98604.1 - 3e-55 186.2 0.0 3.6e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY98604.1 - 3.3e-20 72.5 0.0 5.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY98604.1 - 3.7e-10 39.5 0.0 4.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY98604.1 - 3.7e-08 33.5 0.0 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY98604.1 - 1.2e-06 28.2 0.0 3e-06 26.9 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain pPIWI_RE_Y PF18156.1 ORY98604.1 - 0.0006 20.3 0.2 0.0023 18.4 0.1 1.9 2 0 0 2 2 2 1 pPIWI_RE three-gene island domain Y FeoB_N PF02421.18 ORY98604.1 - 0.001 18.6 0.0 0.004 16.7 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORY98604.1 - 0.0064 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.9 ORY98604.1 - 0.021 14.0 0.2 0.38 9.9 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1_Xtn PF16897.5 ORY98604.1 - 0.029 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 ORY98604.1 - 0.065 12.2 0.1 0.41 9.6 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 ORY98604.1 - 0.088 12.6 0.9 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 ORY98604.1 - 0.18 11.4 0.0 0.71 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Glucan_synthase PF02364.15 ORY98605.1 - 0 1127.2 0.2 0 1126.5 0.2 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORY98605.1 - 5e-31 107.7 1.3 1.1e-29 103.3 1.3 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF2701 PF10857.8 ORY98605.1 - 6.9 6.8 6.8 20 5.3 2.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) K_trans PF02705.16 ORY98606.1 - 2.4e-179 597.3 21.0 2.8e-179 597.1 21.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter RicinB_lectin_2 PF14200.6 ORY98607.1 - 2.6e-18 66.5 3.0 3.4e-08 34.1 0.1 3.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ORY98607.1 - 1.8e-16 60.6 0.0 2.4e-10 40.8 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain DUF1180 PF06679.12 ORY98609.1 - 0.47 10.8 4.7 0.61 10.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FHA PF00498.26 ORY98610.1 - 3.3e-16 59.4 0.5 2.5e-15 56.6 0.0 2.5 3 0 0 3 3 3 1 FHA domain G-patch PF01585.23 ORY98610.1 - 2.6e-10 40.0 1.2 4.1e-10 39.4 1.2 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY98610.1 - 9.7e-10 38.4 0.1 2.2e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 ORY98610.1 - 2.1e-05 24.8 0.1 0.0001 22.6 0.1 2.0 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Clat_adaptor_s PF01217.20 ORY98611.1 - 1.2e-28 99.8 1.2 1.5e-28 99.5 1.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Med31 PF05669.12 ORY98612.1 - 1.7e-37 127.3 11.7 1.7e-37 127.3 11.7 1.5 2 0 0 2 2 2 1 SOH1 HAD_2 PF13419.6 ORY98612.1 - 0.057 13.5 0.1 0.085 12.9 0.1 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Arm PF00514.23 ORY98613.1 - 4.4e-76 248.9 6.9 8.2e-14 51.1 0.0 9.3 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 ORY98613.1 - 9.4e-20 69.9 4.4 1.8e-19 69.1 4.4 1.4 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 ORY98613.1 - 1.1e-19 70.5 3.7 3.3e-08 33.9 0.0 5.9 6 2 1 7 7 6 3 HEAT-like repeat HEAT PF02985.22 ORY98613.1 - 2.4e-17 61.5 1.6 6.1e-06 26.1 0.0 7.5 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 ORY98613.1 - 4.2e-17 62.3 3.2 2.1e-06 28.0 0.1 5.7 3 1 2 7 7 7 3 HEAT repeats RICTOR_V PF14668.6 ORY98613.1 - 0.00013 22.1 1.1 2.4 8.5 0.1 5.1 3 2 3 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 ORY98613.1 - 0.00016 21.7 0.0 0.27 11.3 0.0 3.5 4 0 0 4 4 4 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 ORY98613.1 - 0.00029 20.8 0.0 0.015 15.3 0.0 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 ORY98613.1 - 0.00076 19.9 2.8 5.5 8.0 0.1 5.4 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 ORY98613.1 - 0.0027 16.4 0.0 0.68 8.4 0.0 2.4 1 1 2 3 3 3 3 Adaptin N terminal region IBB PF01749.20 ORY98613.1 - 0.0068 16.8 0.2 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 Importin beta binding domain Rcd1 PF04078.13 ORY98613.1 - 0.16 11.3 0.0 1.1 8.5 0.0 2.1 1 1 1 2 2 2 0 Cell differentiation family, Rcd1-like DUF3874 PF12990.7 ORY98613.1 - 0.17 12.3 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) DUF2786 PF10979.8 ORY98613.1 - 0.74 9.8 3.6 1.7 8.6 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) FGGY_C PF02782.16 ORY98614.1 - 5e-24 85.1 0.0 1.2e-23 83.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY98614.1 - 6e-22 78.4 0.0 4.1e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF3712 PF12505.8 ORY98616.1 - 2e-71 238.1 41.0 4.3e-21 75.5 0.7 7.1 7 0 0 7 7 7 5 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORY98616.1 - 8.1e-16 58.4 14.9 0.073 13.6 0.5 8.1 9 0 0 9 9 9 6 Late embryogenesis abundant protein RhoGEF PF00621.20 ORY98617.1 - 2.1e-49 168.3 0.1 8.5e-49 166.2 0.1 2.2 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 ORY98617.1 - 4.6e-23 80.6 1.8 3.2e-12 45.8 0.3 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY98617.1 - 6.6e-22 77.1 2.1 7.3e-10 38.6 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 ORY98617.1 - 8e-18 63.9 0.0 1.4e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 ORY98617.1 - 5.1e-17 62.1 0.0 5.1e-17 62.1 0.0 3.7 2 1 0 3 3 3 1 Pleckstrin homology domain AMP-binding PF00501.28 ORY98618.1 - 1.2e-97 327.2 0.4 6.6e-97 324.8 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY98618.1 - 7.6e-24 84.5 0.3 2.2e-23 83.0 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORY98618.1 - 2.2e-19 69.1 0.6 5.6e-18 64.6 0.3 2.6 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 ORY98618.1 - 0.058 13.3 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Sugar_tr PF00083.24 ORY98619.1 - 2.7e-109 366.1 25.5 3.2e-109 365.8 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY98619.1 - 6.6e-23 81.2 31.9 6.3e-17 61.5 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY98619.1 - 0.019 14.3 11.5 0.51 9.6 3.2 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB DUF2530 PF10745.9 ORY98619.1 - 0.5 10.6 5.6 2.7 8.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Myb_DNA-bind_7 PF15963.5 ORY98620.1 - 5.2e-26 90.4 0.2 5.2e-26 90.4 0.2 3.1 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORY98620.1 - 5.2e-06 26.6 0.0 9.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ANTH PF07651.16 ORY98621.1 - 2.9e-50 170.8 0.7 4e-50 170.4 0.7 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 ORY98621.1 - 1.6e-05 25.0 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 ENTH domain DUF4050 PF13259.6 ORY98621.1 - 2.3 8.5 5.9 5.4 7.3 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Cadherin_C_2 PF16492.5 ORY98622.1 - 0.00056 20.6 0.8 0.0013 19.4 0.8 1.8 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal Adeno_E3_CR2 PF02439.15 ORY98622.1 - 0.011 15.5 0.2 0.018 14.8 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 ORY98622.1 - 0.1 13.5 0.0 0.14 13.1 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Prominin PF05478.11 ORY98622.1 - 0.11 10.5 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Prominin Shisa PF13908.6 ORY98622.1 - 4.1 7.6 5.8 6.3 7.0 0.0 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF347 PF03988.12 ORY98623.1 - 0.16 12.2 1.8 0.34 11.1 1.8 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) HLH PF00010.26 ORY98624.1 - 1.4e-12 47.3 3.1 1.4e-12 47.3 0.3 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain His_Phos_2 PF00328.22 ORY98625.1 - 3.7e-26 92.4 0.1 1.1e-25 90.8 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3098 PF11297.8 ORY98625.1 - 0.11 12.1 0.0 0.9 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) FHA PF00498.26 ORY98626.1 - 8.1e-07 29.3 0.3 2.2e-06 27.9 0.3 1.7 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 ORY98626.1 - 0.00058 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Forkhead PF00250.18 ORY98626.1 - 0.00089 19.5 0.1 0.0023 18.2 0.0 1.7 2 0 0 2 2 2 1 Forkhead domain CDT1_C PF16679.5 ORY98626.1 - 0.0099 16.3 0.0 0.0099 16.3 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain GMC_oxred_N PF00732.19 ORY98627.1 - 2.1e-50 171.8 0.1 3.1e-49 168.0 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY98627.1 - 5.2e-21 75.7 0.0 1.2e-20 74.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY98627.1 - 5.5e-11 42.2 2.9 5e-07 29.1 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY98627.1 - 1.8e-09 37.6 0.2 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY98627.1 - 9.5e-07 28.3 0.1 9.9e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY98627.1 - 1.4e-06 27.3 2.2 0.0002 20.2 0.5 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 ORY98627.1 - 7e-06 26.2 1.1 1.9e-05 24.8 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY98627.1 - 0.0001 21.7 0.1 0.0002 20.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORY98627.1 - 0.0015 18.0 1.3 0.007 15.8 1.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 ORY98627.1 - 0.0016 18.1 0.1 0.0088 15.7 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ORY98627.1 - 0.0028 16.9 3.5 0.076 12.3 2.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 ORY98627.1 - 0.0043 15.6 0.1 0.0077 14.8 0.1 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor GIDA PF01134.22 ORY98627.1 - 0.028 13.5 2.3 0.1 11.7 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 ORY98627.1 - 0.028 13.6 0.2 0.06 12.6 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 ORY98627.1 - 0.072 12.1 0.8 0.18 10.8 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UBA_4 PF14555.6 ORY98627.1 - 0.1 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain GNAT_acetyltr_2 PF13718.6 ORY98628.1 - 4.1e-100 333.9 4.7 2.2e-99 331.5 0.0 2.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 ORY98628.1 - 2.4e-78 263.1 12.2 2.4e-78 263.1 12.2 2.5 2 1 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 ORY98628.1 - 1.7e-65 220.2 0.4 5.7e-65 218.5 0.0 2.2 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.11 ORY98628.1 - 6.7e-34 115.7 0.1 2.8e-33 113.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 ORY98628.1 - 0.0083 16.4 0.0 0.21 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY98628.1 - 0.017 15.5 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Acetyltransf_7 PF13508.7 ORY98628.1 - 0.022 15.2 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY98628.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SPT2 PF08243.11 ORY98629.1 - 4.7e-20 72.2 16.8 4.7e-20 72.2 16.8 4.0 3 1 1 4 4 4 1 SPT2 chromatin protein Spt20 PF12090.8 ORY98629.1 - 7.5 6.1 10.1 17 4.9 10.1 1.5 1 0 0 1 1 1 0 Spt20 family Med25_VWA PF11265.8 ORY98630.1 - 3.1e-25 89.3 1.2 4e-25 88.9 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A RasGAP PF00616.19 ORY98631.1 - 2e-14 53.8 0.2 2.4e-08 33.9 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 ORY98631.1 - 8.5e-14 51.9 0.3 2.8e-13 50.2 0.3 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT PF02985.22 ORY98631.1 - 0.00044 20.3 0.4 1.1 9.7 0.3 5.5 6 0 0 6 6 6 1 HEAT repeat MOR2-PAG1_C PF14225.6 ORY98631.1 - 0.0081 16.1 0.0 0.041 13.8 0.0 2.3 1 0 0 1 1 1 1 Cell morphogenesis C-terminal CRAL_TRIO PF00650.20 ORY98631.1 - 0.02 14.6 0.1 0.065 13.0 0.1 1.9 1 0 0 1 1 1 0 CRAL/TRIO domain HEAT_2 PF13646.6 ORY98631.1 - 9.6 6.7 7.1 90 3.6 0.1 5.0 5 0 0 5 5 5 0 HEAT repeats CybS PF05328.12 ORY98632.1 - 3.3e-36 123.9 0.1 3.8e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Pkinase PF00069.25 ORY98633.1 - 2.8e-71 240.0 0.0 3.5e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98633.1 - 1e-34 120.0 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98633.1 - 0.00022 20.7 0.0 0.00038 19.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 ORY98634.1 - 3e-50 171.0 0.0 5.9e-50 170.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98634.1 - 5.1e-17 62.0 0.0 7.9e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98634.1 - 0.0023 17.3 0.1 2.1 7.6 0.1 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY98634.1 - 0.03 14.2 0.3 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY98634.1 - 0.13 11.0 0.0 0.28 9.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase PCI PF01399.27 ORY98635.1 - 0.00029 21.3 0.1 0.0014 19.1 0.0 2.3 2 1 0 2 2 2 1 PCI domain Mss4 PF04421.13 ORY98636.1 - 4.1e-24 84.5 0.0 5.3e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein Pyr_redox_2 PF07992.14 ORY98637.1 - 1e-46 159.5 0.0 1.5e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY98637.1 - 9.2e-16 58.2 0.0 1.7e-12 47.7 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 ORY98637.1 - 1.3e-12 48.0 5.3 6.4e-09 36.1 1.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY98637.1 - 8.9e-12 43.7 4.5 3.4e-06 26.2 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY98637.1 - 2.1e-11 42.8 2.5 1.3e-05 24.7 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY98637.1 - 2.9e-07 29.7 2.4 0.0013 18.2 0.1 2.6 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.6 ORY98637.1 - 0.0037 16.6 2.0 0.8 8.9 1.4 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Caleosin PF05042.13 ORY98637.1 - 0.008 16.1 0.3 0.16 11.9 0.0 2.4 1 1 1 2 2 2 1 Caleosin related protein EF-hand_8 PF13833.6 ORY98637.1 - 0.0085 15.9 1.9 1.3 9.0 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 ORY98637.1 - 0.086 12.7 0.9 6.6 6.7 0.1 2.8 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 ORY98637.1 - 0.11 12.4 0.7 19 5.3 0.0 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-H2C2_2 PF13465.6 ORY98640.1 - 1.1e-21 76.2 29.3 6.3e-07 29.5 0.9 5.5 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORY98640.1 - 3.7e-21 74.3 32.0 9.4e-06 25.8 2.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY98640.1 - 7.2e-11 42.0 31.2 0.00082 20.0 1.8 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORY98640.1 - 0.0021 18.6 10.6 2.1 9.1 0.6 3.7 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY98640.1 - 0.0041 17.4 7.9 1.3 9.4 0.1 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORY98640.1 - 0.021 15.5 2.8 0.021 15.5 2.8 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 ORY98640.1 - 0.035 13.9 30.1 0.26 11.1 3.4 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 ORY98640.1 - 0.43 11.0 13.2 9.1 6.8 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 ORY98640.1 - 4 7.5 10.1 3.1 7.9 0.3 3.2 1 1 2 3 3 3 0 Aberrant zinc-finger Peptidase_M1 PF01433.20 ORY98641.1 - 1.5e-83 279.6 1.3 2.3e-83 279.1 1.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORY98641.1 - 3.7e-81 273.1 5.8 1.4e-80 271.2 3.2 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ORY98641.1 - 1.5e-57 194.8 0.4 1.5e-57 194.8 0.4 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Complex1_51K PF01512.17 ORY98642.1 - 7.1e-50 168.8 0.0 1.1e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ORY98642.1 - 7.5e-32 109.3 0.0 1.4e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ORY98642.1 - 2.3e-07 30.6 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 SLBB domain ECH_2 PF16113.5 ORY98643.1 - 1.5e-102 343.6 0.0 2e-102 343.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY98643.1 - 8e-24 84.3 0.0 1.1e-20 74.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-CSL PF05207.13 ORY98644.1 - 1.2e-17 63.3 3.7 1.8e-17 62.8 3.7 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 ORY98644.1 - 1.2e-16 60.5 0.6 1.8e-16 60.0 0.6 1.2 1 0 0 1 1 1 1 DnaJ domain CTP_transf_like PF01467.26 ORY98646.1 - 2.5e-28 99.1 0.2 5e-28 98.1 0.1 1.5 2 0 0 2 2 2 1 Cytidylyltransferase-like SR-25 PF10500.9 ORY98646.1 - 0.025 14.2 3.7 0.039 13.6 3.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5639 PF18690.1 ORY98646.1 - 0.095 12.9 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5639) SH3_1 PF00018.28 ORY98647.1 - 1.3e-31 108.0 0.2 1e-17 63.4 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY98647.1 - 3.6e-30 103.6 0.5 8.7e-17 60.7 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORY98647.1 - 8.2e-21 73.5 0.0 1.2e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 ORY98647.1 - 8.9e-19 67.6 0.2 2.4e-18 66.2 0.2 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 ORY98647.1 - 3.9e-14 52.3 6.1 7.5e-14 51.4 6.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 ORY98647.1 - 0.00055 20.2 0.5 0.0012 19.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_16 PF18348.1 ORY98647.1 - 0.00098 18.9 0.9 0.086 12.7 0.1 2.5 2 0 0 2 2 2 1 Bacterial dipeptidyl-peptidase Sh3 domain RcpB PF16971.5 ORY98647.1 - 0.0088 16.0 4.3 0.016 15.1 4.3 1.3 1 0 0 1 1 1 1 Rough colony protein B, tight adherence - tad - subunit C1_2 PF03107.16 ORY98647.1 - 0.023 15.0 3.6 0.053 13.8 3.6 1.6 1 0 0 1 1 1 0 C1 domain AAA_27 PF13514.6 ORY98647.1 - 0.038 13.6 2.7 0.027 14.0 0.8 1.8 2 0 0 2 2 2 0 AAA domain MutS_II PF05188.17 ORY98647.1 - 0.089 13.1 0.9 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 MutS domain II Peptidase_S46 PF10459.9 ORY98647.1 - 0.16 10.6 14.8 0.035 12.7 11.1 1.7 2 1 0 2 2 2 0 Peptidase S46 T4SS PF07996.11 ORY98647.1 - 0.42 11.0 8.8 0.095 13.1 4.6 2.1 2 0 0 2 2 2 0 Type IV secretion system proteins DUF4085 PF13315.6 ORY98647.1 - 0.63 9.6 8.8 1.2 8.7 5.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) Prominin PF05478.11 ORY98647.1 - 3.1 5.6 6.8 7.7 4.3 6.8 1.7 1 1 0 1 1 1 0 Prominin Cluap1 PF10234.9 ORY98647.1 - 5.7 6.3 15.1 0.5 9.7 9.8 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 Seryl_tRNA_N PF02403.22 ORY98647.1 - 7 6.9 10.3 57 4.0 6.6 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Motile_Sperm PF00635.26 ORY98648.1 - 1.4e-17 63.5 0.2 2.4e-17 62.8 0.2 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASD2 PF08687.11 ORY98648.1 - 0.031 13.8 0.8 0.045 13.3 0.8 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 SOG2 PF10428.9 ORY98648.1 - 0.22 10.7 10.6 0.27 10.4 10.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein ABC_tran_CTD PF16326.5 ORY98648.1 - 0.29 11.4 3.8 0.54 10.5 3.8 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain tRNA_Me_trans PF03054.16 ORY98649.1 - 1.3e-109 366.3 0.0 1.5e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 ORY98649.1 - 0.0036 17.0 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 ORY98649.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 ORY98649.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Pkinase PF00069.25 ORY98650.1 - 8e-50 169.7 0.0 1.1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98650.1 - 1.8e-23 83.2 0.0 2.6e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 ORY98650.1 - 6.4e-05 22.7 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY98650.1 - 7e-05 22.9 0.3 0.00029 20.9 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY98650.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RSN1_7TM PF02714.15 ORY98651.1 - 3.7e-62 210.1 29.6 5.3e-62 209.6 29.6 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY98651.1 - 3.4e-28 98.4 0.7 3.4e-28 98.4 0.7 3.4 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport Tropomyosin_1 PF12718.7 ORY98651.1 - 5.3e-11 42.8 22.6 5.3e-11 42.8 22.6 2.4 2 1 0 2 2 1 1 Tropomyosin like PHM7_cyt PF14703.6 ORY98651.1 - 1.3e-07 32.0 7.2 0.00013 22.2 0.0 3.3 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Tropomyosin PF00261.20 ORY98651.1 - 6.5e-05 22.4 23.4 6.5e-05 22.4 23.4 1.7 2 0 0 2 2 2 1 Tropomyosin DUF4527 PF15030.6 ORY98651.1 - 0.00012 21.7 5.3 0.00022 20.7 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4527) Cast PF10174.9 ORY98651.1 - 0.0011 17.3 11.9 0.0017 16.7 11.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone EzrA PF06160.12 ORY98651.1 - 0.0078 14.4 15.3 0.01 14.1 15.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA IFT57 PF10498.9 ORY98651.1 - 0.031 13.3 8.6 0.061 12.3 8.6 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sugarporin_N PF11471.8 ORY98651.1 - 0.1 12.6 0.2 0.1 12.6 0.2 3.2 2 1 1 3 3 2 0 Maltoporin periplasmic N-terminal extension Importin_rep_4 PF18808.1 ORY98651.1 - 0.22 11.9 1.3 0.37 11.1 0.1 2.0 2 0 0 2 2 1 0 Importin repeat FAM76 PF16046.5 ORY98651.1 - 0.38 10.0 6.3 0.63 9.3 6.3 1.3 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 ORY98651.1 - 0.45 9.8 11.3 1.4 8.2 11.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 ORY98651.1 - 0.56 10.9 10.5 0.65 10.7 3.8 3.1 1 1 1 2 2 2 0 SlyX Cob_adeno_trans PF01923.18 ORY98651.1 - 0.58 10.3 3.4 1.3 9.2 3.4 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase zf-ZPR1 PF03367.13 ORY98651.1 - 0.68 9.8 3.4 1.7 8.4 3.4 1.7 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Spc7 PF08317.11 ORY98651.1 - 0.68 8.8 16.1 1.3 7.8 16.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 ORY98651.1 - 0.7 10.0 8.2 1.4 9.0 8.2 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 ORY98651.1 - 0.89 8.1 11.7 1.5 7.4 11.7 1.3 1 0 0 1 1 1 0 AAA domain DUF1488 PF07369.11 ORY98651.1 - 1.2 9.2 3.5 3.2 7.8 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Exonuc_VII_L PF02601.15 ORY98651.1 - 2 7.9 10.0 1.1 8.8 7.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit GAS PF13851.6 ORY98651.1 - 2.1 7.6 19.5 4.4 6.6 19.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 ORY98651.1 - 2.4 8.5 17.9 0.62 10.5 14.2 1.8 2 0 0 2 2 1 0 Fez1 DUF745 PF05335.13 ORY98651.1 - 3.1 7.5 13.9 6.8 6.4 13.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ABC_tran_CTD PF16326.5 ORY98651.1 - 3.1 8.1 20.4 0.082 13.2 12.0 2.6 2 1 1 3 3 2 0 ABC transporter C-terminal domain Borrelia_P83 PF05262.11 ORY98651.1 - 3.6 6.0 13.9 5.2 5.4 13.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FemAB PF02388.16 ORY98651.1 - 3.8 6.3 8.7 7.5 5.3 8.7 1.4 1 0 0 1 1 1 0 FemAB family DUF1664 PF07889.12 ORY98651.1 - 6.3 6.9 10.4 10 6.2 4.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ORY98651.1 - 6.5 7.1 9.5 9.8 6.5 0.3 3.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 ORY98651.1 - 7.9 6.5 12.1 19 5.2 11.1 2.0 1 1 1 2 2 2 0 Laminin Domain II SBF_like PF13593.6 ORY98652.1 - 8.3e-79 265.1 18.8 1e-78 264.8 18.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) MAPKK1_Int PF08923.10 ORY98653.1 - 6.8e-23 80.7 0.0 9.5e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting TFIIA PF03153.13 ORY98654.1 - 0.013 15.5 10.1 0.017 15.1 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neurensin PF14927.6 ORY98654.1 - 0.016 14.9 0.2 0.016 14.9 0.2 1.6 2 0 0 2 2 2 0 Neurensin WD40 PF00400.32 ORY98655.1 - 5.7e-20 71.3 17.6 0.0036 18.1 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY98655.1 - 3.1e-15 56.2 7.6 5.4e-05 23.4 0.1 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY98655.1 - 1.5e-05 24.9 0.6 0.0016 18.4 0.2 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_3 PF15911.5 ORY98655.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat WD40_like PF17005.5 ORY98655.1 - 0.032 13.6 0.0 0.14 11.4 0.0 2.0 3 0 0 3 3 3 0 WD40-like domain DUF1199 PF06712.11 ORY98655.1 - 0.46 10.5 4.3 0.27 11.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Nup160 PF11715.8 ORY98655.1 - 0.89 8.1 6.7 0.1 11.2 2.2 1.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 WW PF00397.26 ORY98656.1 - 5.1e-10 39.3 0.2 8.7e-10 38.5 0.2 1.4 1 0 0 1 1 1 1 WW domain SUIM_assoc PF16619.5 ORY98656.1 - 1.4e-05 25.0 3.4 0.0027 17.7 0.6 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 FtsX PF02687.21 ORY98656.1 - 0.042 14.3 0.0 0.064 13.7 0.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF2076 PF09849.9 ORY98656.1 - 0.23 11.5 16.4 0.31 11.0 16.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF533 PF04391.12 ORY98656.1 - 0.4 10.2 10.0 1.9 8.0 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF533) UCH PF00443.29 ORY98657.1 - 2.7e-45 154.9 0.0 6e-45 153.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 ORY98657.1 - 8.6e-18 64.0 0.9 1.4e-11 44.1 0.2 3.2 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 ORY98657.1 - 0.0054 16.4 12.4 0.25 10.9 12.4 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2293 PF10056.9 ORY98657.1 - 0.027 14.7 2.0 4.6 7.6 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) Strabismus PF06638.11 ORY98657.1 - 0.033 12.9 0.1 0.057 12.1 0.1 1.3 1 0 0 1 1 1 0 Strabismus protein PUB PF09409.10 ORY98657.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 PUB domain COG2 PF06148.11 ORY98657.1 - 1.3 9.1 4.0 1.3 9.1 0.1 2.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TetR_C_6 PF13977.6 ORY98657.1 - 2.1 8.6 5.6 13 6.1 0.6 3.0 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal RbsD_FucU PF05025.13 ORY98657.1 - 9.8 6.6 6.0 1.5 9.2 0.1 2.7 3 0 0 3 3 3 0 RbsD / FucU transport protein family IMPDH PF00478.25 ORY98658.1 - 1.1e-133 445.6 5.0 1.3e-133 445.4 5.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ORY98658.1 - 2.7e-15 56.5 0.2 7.5e-08 32.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 ORY98658.1 - 2.6e-09 36.6 1.3 5.3e-09 35.6 1.3 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 ORY98658.1 - 3.3e-05 23.4 9.3 0.0072 15.8 7.4 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 ORY98658.1 - 0.00013 21.5 2.8 0.0025 17.3 0.6 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 ORY98658.1 - 0.0015 17.9 2.4 0.0023 17.3 1.0 1.9 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 ORY98658.1 - 0.043 13.2 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 KDPG and KHG aldolase Glu_synthase PF01645.17 ORY98658.1 - 0.049 12.8 2.1 0.11 11.7 2.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase YpsA PF06908.11 ORY98658.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Radical_SAM PF04055.21 ORY98658.1 - 0.19 12.1 0.0 9.7 6.5 0.0 3.1 2 1 1 3 3 3 0 Radical SAM superfamily Pkinase PF00069.25 ORY98660.1 - 6e-44 150.4 0.0 7.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98660.1 - 1.1e-29 103.6 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98660.1 - 1.7e-07 30.9 0.0 3.1e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY98660.1 - 6.4e-06 25.2 0.0 9.1e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY98660.1 - 0.039 13.9 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_25 PF13649.6 ORY98661.1 - 9.5e-18 64.7 0.0 3.9e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY98661.1 - 1.6e-17 63.9 0.0 2.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY98661.1 - 6.2e-17 62.0 0.0 1.4e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY98661.1 - 5.2e-12 45.8 0.0 3.3e-11 43.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY98661.1 - 7.4e-08 33.1 0.0 3.4e-07 30.9 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY98661.1 - 8.3e-08 31.8 0.0 3.3e-07 29.9 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORY98661.1 - 1.6e-06 28.1 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 ORY98661.1 - 3.4e-06 26.6 0.0 0.00018 21.0 0.0 2.7 1 1 0 1 1 1 1 Putative methyltransferase CheR PF01739.18 ORY98661.1 - 0.0004 19.9 0.0 0.029 13.9 0.0 2.5 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 ORY98661.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 ORY98661.1 - 0.0036 16.9 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ORY98661.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ORY98661.1 - 0.0059 16.0 0.0 0.02 14.3 0.0 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 ORY98661.1 - 0.0095 15.4 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 ORY98661.1 - 0.05 13.6 0.1 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 ORY98661.1 - 0.066 12.5 0.0 0.17 11.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.15 ORY98661.1 - 0.076 12.3 0.1 4.9 6.4 0.0 2.5 3 0 0 3 3 3 0 rRNA small subunit methyltransferase G Thioredoxin_14 PF18402.1 ORY98661.1 - 0.083 12.8 0.9 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain AdoMet_MTase PF07757.13 ORY98661.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Androgen_recep PF02166.16 ORY98661.1 - 1.2 7.9 5.4 1.8 7.3 5.4 1.2 1 0 0 1 1 1 0 Androgen receptor PCI PF01399.27 ORY98662.1 - 1.8e-06 28.4 0.6 5.5e-06 26.8 0.6 1.8 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 ORY98662.1 - 0.0058 16.5 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain TilS PF09179.11 ORY98662.1 - 0.026 15.0 0.5 0.1 13.1 0.1 2.2 2 0 0 2 2 2 0 TilS substrate binding domain PhoLip_ATPase_C PF16212.5 ORY98663.1 - 9.3e-74 248.3 29.9 9.3e-74 248.3 29.9 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY98663.1 - 9.1e-23 79.7 1.5 9.1e-23 79.7 1.5 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY98663.1 - 8.6e-13 48.2 0.0 5.9e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY98663.1 - 1.3e-07 32.1 4.6 0.0012 19.1 0.6 3.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY98663.1 - 9.7e-05 22.0 0.0 9.7e-05 22.0 0.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY98663.1 - 0.0013 18.5 0.8 0.0062 16.3 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 ORY98663.1 - 0.0046 17.0 1.9 0.0046 17.0 1.9 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Peptidase_U32 PF01136.19 ORY98663.1 - 0.021 14.0 0.6 0.04 13.1 0.6 1.4 1 0 0 1 1 1 0 Peptidase family U32 DUF2457 PF10446.9 ORY98663.1 - 0.051 12.7 21.4 0.14 11.3 21.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.6 ORY98663.1 - 0.64 10.3 10.3 3.3 8.0 10.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RRN3 PF05327.11 ORY98663.1 - 1 7.8 11.5 1.8 7.0 11.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 ORY98663.1 - 1.2 7.2 17.7 2.2 6.3 17.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 ORY98663.1 - 1.6 6.8 11.8 3.1 5.9 11.8 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 ORY98663.1 - 2.2 7.6 13.0 0.15 11.5 7.2 1.8 2 0 0 2 2 2 0 SDA1 DUF2207 PF09972.9 ORY98663.1 - 5.7 5.6 6.1 51 2.4 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Synaptobrevin PF00957.21 ORY98664.1 - 6.4e-31 106.0 1.5 9.9e-31 105.4 1.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY98664.1 - 7e-31 106.1 0.0 1.4e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain MCU PF04678.13 ORY98664.1 - 0.065 13.3 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DnaJ_C PF01556.18 ORY98665.1 - 7.1e-42 143.0 0.2 9.3e-42 142.6 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY98665.1 - 1.8e-25 88.9 1.5 3.1e-25 88.1 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY98665.1 - 9.7e-16 57.9 18.1 1.7e-15 57.1 18.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY98665.1 - 0.034 14.1 13.6 0.49 10.4 1.5 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORY98665.1 - 9.7 6.2 11.6 13 5.8 1.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Terminase_5 PF06056.12 ORY98666.1 - 0.022 14.6 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) ATP-synt_C PF00137.21 ORY98668.1 - 4.8e-26 90.9 26.5 2.7e-14 53.3 9.8 2.8 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.24 ORY98668.1 - 0.015 14.9 0.2 0.015 14.9 0.2 2.6 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CPL PF08144.11 ORY98669.1 - 2.3e-42 144.7 7.0 9.1e-40 136.3 0.4 4.2 3 2 1 4 4 4 2 CPL (NUC119) domain PUF PF00806.19 ORY98669.1 - 2.5e-06 26.9 0.0 0.38 10.5 0.0 5.5 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat Bmt2 PF11968.8 ORY98669.1 - 0.06 13.2 0.6 0.1 12.5 0.1 1.6 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Asp_protease_2 PF13650.6 ORY98670.1 - 0.0014 19.2 0.0 0.0021 18.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 ORY98670.1 - 0.012 16.1 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2849 PF11011.8 ORY98670.1 - 0.08 13.6 0.5 0.11 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) SWIRM PF04433.17 ORY98671.1 - 0.059 13.7 0.5 10 6.6 0.1 2.6 2 0 0 2 2 2 0 SWIRM domain DUF3648 PF12364.8 ORY98671.1 - 0.081 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) SR-25 PF10500.9 ORY98672.1 - 0.054 13.1 1.0 0.073 12.7 1.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DLP_helical PF18709.1 ORY98672.1 - 0.14 11.3 0.7 0.19 10.9 0.7 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain SH3-RhoG_link PF16609.5 ORY98673.1 - 0.058 13.1 0.6 0.11 12.2 0.3 1.6 1 1 0 1 1 1 0 SH3-RhoGEF linking unstructured region AFT PF08731.11 ORY98674.1 - 0.00024 21.5 1.5 0.00093 19.6 1.5 2.1 1 0 0 1 1 1 1 Transcription factor AFT SWIM PF04434.17 ORY98674.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 SWIM zinc finger ATP-synt_ab PF00006.25 ORY98678.1 - 3.7e-109 363.4 0.0 5.2e-109 362.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 ORY98678.1 - 3.2e-44 149.7 0.0 6.1e-44 148.8 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 ORY98678.1 - 5.4e-13 49.3 2.2 5.4e-13 49.3 2.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Mito_carr PF00153.27 ORY98679.1 - 2.9e-61 203.4 0.9 1e-19 70.3 0.6 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2618 PF10940.8 ORY98679.1 - 0.13 12.1 0.6 12 5.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) UQ_con PF00179.26 ORY98680.1 - 1.1e-46 157.9 0.0 1.4e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rad10 PF03834.14 ORY98681.1 - 8.6e-46 154.7 0.4 1.3e-45 154.0 0.4 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 ORY98681.1 - 4.4e-07 30.4 0.0 8.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 ORY98681.1 - 0.0034 17.5 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif PTPLA PF04387.14 ORY98681.1 - 0.014 15.1 0.3 2.8 7.6 0.1 2.2 1 1 1 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA Pkinase PF00069.25 ORY98682.1 - 5.5e-59 199.7 0.0 8.3e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98682.1 - 1.1e-28 100.3 0.0 1.8e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY98682.1 - 1.1e-09 38.8 0.4 5e-09 36.7 0.4 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain PX PF00787.24 ORY98682.1 - 1.8e-05 24.7 3.7 1.8e-05 24.7 3.7 2.6 3 0 0 3 3 3 1 PX domain Kinase-like PF14531.6 ORY98682.1 - 0.0018 17.7 0.4 0.0032 16.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY98682.1 - 0.0052 15.8 0.0 0.0093 14.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY98682.1 - 0.024 14.3 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY98682.1 - 0.031 14.2 0.5 0.068 13.1 0.5 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Xylo_C PF12529.8 ORY98682.1 - 0.092 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Xylosyltransferase C terminal AAA PF00004.29 ORY98683.1 - 0.00026 21.4 0.0 0.00058 20.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY98683.1 - 0.0003 21.0 0.0 0.0004 20.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORY98683.1 - 0.00066 19.4 0.0 0.00083 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY98683.1 - 0.00078 19.4 0.1 0.0016 18.4 0.1 1.6 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 ORY98683.1 - 0.00082 19.9 0.0 0.0011 19.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 ORY98683.1 - 0.0036 17.3 0.0 0.029 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY98683.1 - 0.0041 17.4 0.1 0.01 16.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY98683.1 - 0.0048 16.2 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 ORY98683.1 - 0.0051 16.4 0.3 0.48 10.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY98683.1 - 0.021 15.3 0.0 0.028 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY98683.1 - 0.024 15.0 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 ORY98683.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 ORY98683.1 - 0.026 14.3 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 ORY98683.1 - 0.027 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 ORY98683.1 - 0.039 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 ORY98683.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 ORY98683.1 - 0.087 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 ORY98683.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 ORY98683.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 ORY98683.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B SNAPc_SNAP43 PF09808.9 ORY98684.1 - 1.2e-26 93.8 0.3 2e-26 93.1 0.3 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 RRM_1 PF00076.22 ORY98685.1 - 8.8e-05 22.3 0.0 0.0031 17.3 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.12 ORY98685.1 - 1.8 7.9 41.0 3.6 6.9 41.0 1.5 1 1 0 1 1 1 0 SDA1 adh_short PF00106.25 ORY98686.1 - 2.5e-16 59.7 0.0 3.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY98686.1 - 4.4e-11 42.8 0.0 5.1e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TRF PF08558.10 ORY98686.1 - 0.038 13.6 0.0 0.098 12.2 0.0 1.6 1 1 0 1 1 1 0 Telomere repeat binding factor (TRF) PPR_1 PF12854.7 ORY98686.1 - 0.11 12.2 0.8 0.26 11.0 0.8 1.6 1 0 0 1 1 1 0 PPR repeat C1_1 PF00130.22 ORY98687.1 - 1.7e-10 40.6 16.2 9.7e-08 31.8 2.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.6 ORY98687.1 - 1.2e-05 24.3 0.1 0.00043 19.2 0.0 2.2 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 C1_2 PF03107.16 ORY98687.1 - 0.82 10.0 20.3 0.018 15.3 3.3 2.6 2 0 0 2 2 2 0 C1 domain PHD_4 PF16866.5 ORY98687.1 - 1.6 8.8 9.7 0.27 11.4 1.4 2.8 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 ORY98687.1 - 5.5 7.3 13.9 0.95 9.8 3.0 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain Glycogen_syn PF05693.13 ORY98689.1 - 0 1083.0 0.0 0 1082.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 ORY98689.1 - 2.3e-06 27.5 0.2 6e-06 26.1 0.2 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 ORY98689.1 - 3.4e-06 27.2 0.4 6.9e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ORY98689.1 - 2e-05 25.0 0.0 0.0056 17.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORY98689.1 - 2e-05 24.2 0.0 0.0013 18.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY98689.1 - 0.00012 22.6 0.1 0.00023 21.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain 4HBT PF03061.22 ORY98690.1 - 1.8e-12 47.4 0.1 3e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 ORY98690.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) SH3_9 PF14604.6 ORY98691.1 - 3.5e-12 46.0 0.1 5.5e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY98691.1 - 2.9e-05 23.6 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY98691.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_60s PF00428.19 ORY98691.1 - 1.5 9.5 7.3 2.3 8.9 7.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.13 ORY98691.1 - 9.3 6.1 8.1 12 5.8 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH_2 PF14608.6 ORY98692.1 - 8.3e-16 57.8 56.8 3.9e-05 24.0 8.4 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger cobW PF02492.19 ORY98693.1 - 8.2e-40 136.3 0.2 1.1e-39 135.8 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORY98693.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain tRNA_anti-codon PF01336.25 ORY98693.1 - 0.025 14.6 0.0 0.066 13.2 0.0 1.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain SRP54 PF00448.22 ORY98693.1 - 0.032 13.9 0.1 0.084 12.5 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Pox_A32 PF04665.12 ORY98693.1 - 0.038 13.4 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DHOase PF12890.7 ORY98693.1 - 0.038 13.9 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Dihydro-orotase-like RsgA_GTPase PF03193.16 ORY98693.1 - 0.073 13.0 0.3 3.7 7.4 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_11 PF13086.6 ORY98693.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY98693.1 - 0.1 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY98693.1 - 0.14 12.3 0.1 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Beta_elim_lyase PF01212.21 ORY98694.1 - 3.3e-74 249.8 0.0 4.3e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY98694.1 - 0.00023 20.6 0.0 0.0004 19.8 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ORY98694.1 - 0.00031 20.0 0.0 0.00061 19.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II GFA PF04828.14 ORY98695.1 - 2.5e-16 59.8 0.0 3.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.18 ORY98696.1 - 4.3e-30 104.6 0.0 9.6e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY98696.1 - 1.6e-05 24.9 10.5 3.3e-05 23.9 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.18 ORY98697.1 - 9.5e-60 202.0 0.0 2.9e-59 200.4 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 ORY98698.1 - 3.8e-37 128.0 31.8 3.8e-37 128.0 31.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3671 PF12420.8 ORY98698.1 - 4.8 7.3 12.1 3.5 7.7 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function Cupin_2 PF07883.11 ORY98699.1 - 7.5e-21 73.6 0.8 4.5e-16 58.3 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 ORY98699.1 - 2.5e-06 27.2 0.0 0.00076 19.1 0.0 2.3 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.19 ORY98699.1 - 0.0002 21.3 0.2 0.00039 20.3 0.2 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ORY98699.1 - 0.03 14.0 0.0 0.31 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Auxin_BP PF02041.16 ORY98699.1 - 0.06 13.0 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Auxin binding protein DMSP_lyase PF16867.5 ORY98699.1 - 0.066 12.9 0.1 0.23 11.1 0.1 1.9 2 1 0 2 2 2 0 Dimethlysulfonioproprionate lyase FAD_binding_3 PF01494.19 ORY98700.1 - 2.6e-28 99.3 0.0 3.2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY98700.1 - 7.2e-07 28.7 4.1 0.00072 18.9 1.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY98700.1 - 1e-06 28.6 6.9 0.0067 16.1 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY98700.1 - 2.9e-06 26.4 0.2 0.012 14.5 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 ORY98700.1 - 3e-06 27.4 0.2 8.4e-06 25.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY98700.1 - 5e-06 26.1 0.2 0.055 12.8 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ORY98700.1 - 1.1e-05 24.8 2.8 1.8e-05 24.0 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORY98700.1 - 1.5e-05 24.2 5.0 0.00016 20.9 5.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY98700.1 - 2.7e-05 24.7 2.7 0.0021 18.6 1.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY98700.1 - 0.00037 19.7 1.5 0.00085 18.5 1.5 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY98700.1 - 0.0012 18.2 0.5 0.0058 15.9 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY98700.1 - 0.0018 17.7 4.7 0.0073 15.7 4.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY98700.1 - 0.0091 14.7 1.7 0.0091 14.7 1.7 1.7 2 0 0 2 2 2 1 HI0933-like protein adh_short PF00106.25 ORY98701.1 - 3.5e-17 62.5 0.1 1.5e-16 60.5 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY98701.1 - 1.8e-07 31.0 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY98701.1 - 0.00088 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Trypan_PARP PF05887.11 ORY98702.1 - 0.027 14.5 0.8 0.043 13.8 0.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf_C2H2_ZHX PF18387.1 ORY98702.1 - 0.45 10.2 3.6 0.26 11.0 0.3 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain MnmE_helical PF12631.7 ORY98703.1 - 6.7e-50 170.1 0.1 8.1e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 ORY98703.1 - 2.7e-37 127.6 0.0 5.5e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 ORY98703.1 - 1.2e-19 70.5 0.0 3e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY98703.1 - 1.1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY98703.1 - 3.6e-05 23.9 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 ORY98703.1 - 0.00023 21.7 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 ORY98703.1 - 0.0023 18.2 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORY98703.1 - 0.011 15.7 0.0 0.047 13.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 ORY98703.1 - 0.012 16.1 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY98703.1 - 0.018 15.4 0.1 0.32 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 ORY98703.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 ORY98703.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family GBP PF02263.19 ORY98703.1 - 0.063 12.5 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_29 PF13555.6 ORY98703.1 - 0.12 12.2 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY98704.1 - 4.5e-23 81.5 0.1 1.7e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY98704.1 - 1.4e-09 38.3 0.6 0.00052 20.1 0.3 2.8 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 ORY98704.1 - 6.4e-09 35.9 0.1 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY98704.1 - 5.9e-06 25.9 0.0 8.3e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORY98704.1 - 3.9e-05 23.3 0.6 0.0051 16.4 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 ORY98704.1 - 0.0016 18.2 0.2 0.0031 17.3 0.2 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 ORY98704.1 - 0.0019 17.5 2.2 0.13 11.5 2.2 2.6 1 1 0 1 1 1 1 Septin AAA_22 PF13401.6 ORY98704.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 ORY98704.1 - 0.0043 16.5 0.1 0.0075 15.7 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY98704.1 - 0.0064 16.1 0.2 0.37 10.4 0.0 2.2 2 0 0 2 2 2 1 Ras family Roc PF08477.13 ORY98704.1 - 0.008 16.4 0.1 0.02 15.1 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 ORY98704.1 - 0.032 14.3 0.2 0.11 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 ORY98704.1 - 0.038 13.3 0.1 0.081 12.2 0.0 1.7 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 ORY98704.1 - 0.041 14.4 0.6 0.34 11.4 0.6 2.2 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 ORY98704.1 - 0.066 12.5 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2235 PF09994.9 ORY98705.1 - 3.7e-64 216.8 0.0 1.2e-63 215.2 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ras PF00071.22 ORY98706.1 - 4.6e-51 172.6 0.4 5.3e-51 172.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY98706.1 - 1.2e-36 125.5 0.3 1.7e-36 125.1 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY98706.1 - 1.3e-15 57.3 0.1 1.5e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY98706.1 - 1.5e-07 31.0 0.1 1.9e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY98706.1 - 1.2e-05 25.4 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY98706.1 - 0.00013 21.5 0.1 0.00018 21.0 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY98706.1 - 0.00013 22.4 0.0 0.00019 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY98706.1 - 0.00016 21.7 0.2 0.14 12.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY98706.1 - 0.0026 17.3 0.4 0.0089 15.6 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 ORY98706.1 - 0.014 14.9 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 ORY98706.1 - 0.021 14.5 0.2 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ORY98706.1 - 0.064 13.5 0.1 0.17 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY98706.1 - 0.09 12.8 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ORY98706.1 - 0.15 11.7 0.1 0.41 10.3 0.1 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Got1 PF04178.12 ORY98707.1 - 7.4e-15 55.4 15.1 9.1e-15 55.1 15.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1129 PF06570.11 ORY98707.1 - 8.9 5.7 8.5 12 5.3 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2839 PF10999.8 ORY98708.1 - 0.051 13.9 0.8 0.12 12.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Mannosyl_trans3 PF11051.8 ORY98709.1 - 1.4e-43 149.3 0.0 6.3e-42 143.8 0.0 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative GBR2_CC PF18455.1 ORY98709.1 - 2.3 8.4 5.2 0.51 10.5 0.4 2.1 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF1033 PF06279.11 ORY98710.1 - 0.0096 16.1 0.3 0.031 14.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1033) Metallophos PF00149.28 ORY98711.1 - 9.3e-39 134.0 0.1 1.3e-38 133.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY98711.1 - 0.001 19.5 0.2 0.0021 18.5 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 ORY98711.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 ORY98711.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Aldo_ket_red PF00248.21 ORY98712.1 - 3.4e-47 161.1 0.0 5e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family APG17 PF04108.12 ORY98713.1 - 2e-05 23.9 7.4 0.0036 16.5 0.3 3.4 3 1 0 3 3 3 2 Autophagy protein Apg17 KxDL PF10241.9 ORY98713.1 - 3.5 8.0 5.3 1.8 8.9 0.7 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein FAM184 PF15665.5 ORY98714.1 - 1.7 8.4 63.2 18 5.1 51.2 4.2 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B ATG11 PF10377.9 ORY98715.1 - 1.2e-25 90.1 0.4 2.2e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 11 LSM PF01423.22 ORY98716.1 - 5.5e-18 64.4 0.1 6.9e-18 64.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain DnaJ-X PF14308.6 ORY98717.1 - 4.7e-58 196.1 0.1 4.7e-58 196.1 0.1 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORY98717.1 - 2.7e-27 94.7 3.7 2.7e-27 94.7 3.7 2.2 2 0 0 2 2 2 1 DnaJ domain Adaptin_binding PF10199.9 ORY98717.1 - 0.11 13.0 6.1 0.28 11.8 6.1 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CagY_M PF07337.11 ORY98717.1 - 4.5 7.0 7.6 5.7 6.6 1.5 2.8 2 0 0 2 2 2 0 DC-EC Repeat RRP7 PF12923.7 ORY98718.1 - 1.2e-28 99.6 15.3 2e-28 98.9 15.3 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 ORY98718.1 - 3e-10 40.1 0.5 1.1e-09 38.3 0.0 2.1 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 ORY98718.1 - 0.0024 17.6 0.2 0.017 15.0 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-alpha PF00503.20 ORY98719.1 - 2e-109 366.0 0.0 2.6e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY98719.1 - 1.2e-12 47.7 0.2 1.1e-06 28.3 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY98719.1 - 0.00015 21.2 0.5 0.02 14.2 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY98719.1 - 0.013 15.0 0.0 0.97 8.9 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 ORY98719.1 - 0.028 14.6 0.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ORY98719.1 - 0.046 13.1 0.2 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 ORY98719.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY98719.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.12 ORY98720.1 - 1.1e-19 70.4 5.3 4.6e-06 27.1 0.0 4.3 4 0 0 4 4 4 3 Sel1 repeat TPR_4 PF07721.14 ORY98720.1 - 4.1 8.3 6.0 3.5 8.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 ORY98721.1 - 1.3e-82 278.0 1.7 3e-40 138.4 0.0 4.2 4 0 0 4 4 4 4 Protein of unknown function (DUF3808) TPR_2 PF07719.17 ORY98721.1 - 9.7e-07 28.4 1.0 1.2e-05 25.0 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY98721.1 - 4.2e-06 27.0 2.1 1.5e-05 25.2 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY98721.1 - 1.1e-05 25.0 0.1 3.3e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98721.1 - 1.6e-05 24.8 0.3 0.00021 21.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY98721.1 - 0.0012 18.7 0.1 0.007 16.3 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY98721.1 - 0.0046 16.8 0.4 0.0046 16.8 0.4 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY98721.1 - 0.01 15.2 0.7 0.01 15.2 0.7 2.8 2 1 0 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 ORY98721.1 - 0.044 14.6 0.1 0.044 14.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY98721.1 - 0.046 13.4 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 TPR repeat TPR_4 PF07721.14 ORY98721.1 - 0.074 13.7 2.4 0.093 13.4 0.4 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98721.1 - 0.15 12.7 3.9 0.23 12.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY98721.1 - 0.67 10.7 8.2 15 6.5 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 ORY98721.1 - 6.4 6.9 11.3 0.22 11.6 0.2 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Glyco_transf_15 PF01793.16 ORY98722.1 - 5e-80 269.2 10.2 6.3e-80 268.9 10.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2185 PF09951.9 ORY98722.1 - 0.078 12.8 0.5 0.27 11.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) EGF_3 PF12947.7 ORY98722.1 - 0.097 12.9 1.7 0.17 12.1 1.7 1.4 1 0 0 1 1 1 0 EGF domain Aldo_ket_red PF00248.21 ORY98723.1 - 1.2e-52 179.0 0.0 1.4e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_TAC_14 PF16462.5 ORY98723.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC START PF01852.19 ORY98725.1 - 2.2e-12 46.8 0.0 3.1e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 START domain CE2_N PF17996.1 ORY98725.1 - 0.074 13.0 0.5 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal SHD1 PF03983.12 ORY98726.1 - 2.1e-13 49.9 0.0 3.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 A_deamin PF02137.18 ORY98727.1 - 1.3e-71 241.7 1.1 1.6e-71 241.5 1.1 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF4726 PF15855.5 ORY98727.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) RNB PF00773.19 ORY98729.1 - 1e-67 228.8 0.0 1.4e-67 228.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY98729.1 - 1.6e-19 69.7 0.0 4e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORY98729.1 - 7.5e-18 64.7 0.1 2.9e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 ORY98729.1 - 0.0023 18.1 0.1 1.8 8.8 0.0 3.2 3 0 0 3 3 3 2 Cold shock domain MFS_1 PF07690.16 ORY98730.1 - 2.4e-45 155.0 42.3 3.5e-38 131.5 27.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY98730.1 - 2e-14 53.3 7.4 2e-14 53.3 7.4 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 ORY98730.1 - 4.2e-06 25.4 4.7 4.2e-06 25.4 4.7 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector CRM1_repeat_3 PF18787.1 ORY98730.1 - 0.26 11.4 1.9 0.55 10.4 0.7 2.2 1 1 1 2 2 2 0 CRM1 / Exportin repeat 3 bZIP_2 PF07716.15 ORY98731.1 - 1.2e-05 25.3 8.4 1.2e-05 25.3 8.4 2.5 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY98731.1 - 0.011 15.8 15.2 0.015 15.3 5.6 2.5 2 1 0 2 2 2 0 bZIP transcription factor APC_N_CC PF16689.5 ORY98731.1 - 0.038 14.0 1.0 0.078 13.1 1.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Syntaxin-6_N PF09177.11 ORY98731.1 - 0.054 14.1 3.3 0.35 11.5 3.4 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ATG16 PF08614.11 ORY98731.1 - 0.11 12.7 9.6 0.038 14.2 6.9 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SIKE PF05769.11 ORY98731.1 - 0.14 12.0 3.3 0.59 10.1 3.3 2.0 1 1 0 1 1 1 0 SIKE family TSC22 PF01166.18 ORY98731.1 - 0.31 11.4 3.2 0.49 10.7 0.2 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 ORY98731.1 - 0.38 11.0 8.1 1.9 8.7 0.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 NUDE_C PF04880.13 ORY98731.1 - 2 8.9 16.1 1.9 8.9 6.7 2.2 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region CUE PF02845.16 ORY98732.1 - 0.011 15.4 0.1 15 5.4 0.0 3.6 3 0 0 3 3 3 0 CUE domain ArAE_2 PF10334.9 ORY98733.1 - 9e-20 71.5 0.1 1.6e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY98733.1 - 1.7e-13 50.8 16.6 1.7e-13 50.8 16.6 2.9 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 ORY98733.1 - 1.5e-05 24.2 5.3 1.5e-05 24.2 5.3 2.3 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 ORY98733.1 - 0.00021 20.0 8.5 0.00021 20.0 8.5 3.3 3 1 0 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 ORY98733.1 - 0.028 13.3 3.4 0.063 12.1 3.4 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter BUD22 PF09073.10 ORY98733.1 - 2.2 7.5 14.7 69 2.6 0.0 2.1 2 0 0 2 2 2 0 BUD22 DUF3245 PF11595.8 ORY98733.1 - 2.7 8.5 10.2 0.047 14.2 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Nop14 PF04147.12 ORY98733.1 - 3.7 5.6 15.1 5.5 5.1 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family Sel1 PF08238.12 ORY98736.1 - 1.4e-38 130.4 21.6 1.6e-07 31.8 0.3 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 ORY98736.1 - 0.14 12.8 5.6 11 6.9 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Tmemb_14 PF03647.13 ORY98737.1 - 6.3e-27 94.1 12.9 7.1e-27 94.0 12.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CPP1-like PF11833.8 ORY98737.1 - 0.028 14.1 4.8 0.031 13.9 4.8 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PT-VENN PF04829.13 ORY98737.1 - 9.1 6.4 7.9 88 3.3 8.0 2.2 1 1 1 2 2 2 0 Pre-toxin domain with VENN motif DUF966 PF06136.13 ORY98738.1 - 6.3 6.4 15.2 14 5.2 14.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF966) START PF01852.19 ORY98739.1 - 2.5e-16 59.7 0.0 3.7e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 START domain RabGAP-TBC PF00566.18 ORY98740.1 - 1.1e-42 146.1 0.3 1.1e-42 146.1 0.3 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Seryl_tRNA_N PF02403.22 ORY98740.1 - 0.0045 17.2 3.5 0.0045 17.2 3.5 3.3 2 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 ORY98740.1 - 0.29 11.3 46.1 0.15 12.2 16.1 3.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Fungal_TACC PF12709.7 ORY98740.1 - 0.97 9.9 23.8 2.4 8.7 1.6 4.6 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Laminin_II PF06009.12 ORY98740.1 - 1.6 8.8 19.0 0.67 10.0 4.2 3.0 3 0 0 3 3 3 0 Laminin Domain II GAS PF13851.6 ORY98740.1 - 7.5 5.8 33.6 0.23 10.8 3.4 4.1 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 ORY98740.1 - 8.1 5.9 33.5 2.2 7.8 19.2 2.8 2 0 0 2 2 2 0 Intermediate filament protein Velvet PF11754.8 ORY98741.1 - 1.3e-63 215.2 7.8 1.4e-61 208.7 2.2 2.7 2 1 0 2 2 2 1 Velvet factor DEC-1_N PF04625.13 ORY98741.1 - 2.2 7.2 11.3 3.4 6.6 11.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Sugar_tr PF00083.24 ORY98742.1 - 7.6e-92 308.5 16.1 9.3e-92 308.2 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY98742.1 - 1.8e-24 86.3 44.9 1e-18 67.4 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY98742.1 - 0.03 12.8 8.0 0.014 13.9 4.9 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.6 ORY98742.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Rick_17kDa_Anti PF05433.15 ORY98742.1 - 4.6 7.2 11.0 0.06 13.2 2.8 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain NAP PF00956.18 ORY98743.1 - 1.7e-17 63.5 19.2 1.3e-16 60.5 1.5 3.5 2 1 2 4 4 4 3 Nucleosome assembly protein (NAP) PcfK PF14058.6 ORY98743.1 - 0.0014 18.9 2.8 0.0014 18.9 2.8 2.4 2 1 1 3 3 3 1 PcfK-like protein PEHE PF15275.6 ORY98743.1 - 0.063 13.9 0.0 0.063 13.9 0.0 1.8 2 0 0 2 2 2 0 PEHE domain TLP-20 PF06088.11 ORY98743.1 - 1.5 8.7 11.8 1.3 8.9 1.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ribosomal_L18 PF17135.4 ORY98744.1 - 3.2e-89 297.3 4.9 3.5e-89 297.2 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORY98744.1 - 1.2 9.8 4.2 0.25 12.0 0.2 2.0 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MFS_1 PF07690.16 ORY98745.1 - 2.1e-34 119.0 7.9 2.1e-34 119.0 7.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY98745.1 - 0.0033 16.4 22.8 0.11 11.3 8.1 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter DUF4131 PF13567.6 ORY98745.1 - 0.39 10.3 0.0 0.39 10.3 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) OATP PF03137.20 ORY98745.1 - 0.5 8.6 4.5 3.7 5.7 0.2 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Wzy_C PF04932.15 ORY98745.1 - 1.1 8.8 11.2 0.63 9.7 0.1 2.9 2 1 0 2 2 2 0 O-Antigen ligase NDT80_PhoG PF05224.12 ORY98746.1 - 5.4e-36 124.6 0.0 5.4e-36 124.6 0.0 3.3 3 1 1 4 4 4 1 NDT80 / PhoG like DNA-binding family RskA PF10099.9 ORY98746.1 - 0.2 11.9 18.2 1.9 8.7 4.9 2.8 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Mcm10 PF09332.11 ORY98746.1 - 2.6 7.4 6.4 5.7 6.3 6.4 1.5 1 0 0 1 1 1 0 Mcm10 replication factor Got1 PF04178.12 ORY98748.1 - 1.6e-17 63.9 13.2 1.9e-17 63.7 13.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family AATF-Che1 PF13339.6 ORY98749.1 - 5e-31 108.2 2.9 5e-31 108.2 2.9 3.5 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 ORY98749.1 - 2.3e-06 28.0 2.2 2.3e-06 28.0 2.2 2.8 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal YojJ PF10372.9 ORY98749.1 - 3.1 8.0 5.8 8.4 6.6 0.2 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Tfb4 PF03850.14 ORY98749.1 - 3.6 7.0 5.8 5.1 6.5 3.1 2.3 2 0 0 2 2 2 0 Transcription factor Tfb4 Vicilin_N PF04702.12 ORY98749.1 - 7.2 6.4 22.0 1.6 8.5 17.8 2.0 2 0 0 2 2 2 0 Vicilin N terminal region OrfB_Zn_ribbon PF07282.11 ORY98752.1 - 2.8e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY98753.1 - 0.0029 17.5 0.1 0.0048 16.8 0.1 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Asp PF00026.23 ORY98754.1 - 2.6e-68 230.8 0.0 4e-36 125.0 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY98754.1 - 3e-11 43.9 1.2 1.1e-08 35.6 1.0 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY98754.1 - 0.0018 18.1 0.1 0.03 14.1 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ORY98754.1 - 0.0072 16.9 0.3 0.62 10.7 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY98754.1 - 0.0075 16.9 1.4 0.19 12.4 0.1 2.8 2 1 0 2 2 2 1 Aspartyl protease Asp PF00026.23 ORY98755.1 - 1e-69 235.4 2.6 2.4e-69 234.2 2.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY98755.1 - 1.9e-10 41.3 7.9 3.4e-07 30.7 0.2 3.7 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ORY98755.1 - 0.037 14.6 0.4 2.3 8.8 0.1 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 ORY98756.1 - 2.2e-68 231.0 3.2 3.4e-68 230.4 3.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY98756.1 - 5.4e-10 39.8 13.8 6.8e-08 32.9 0.1 3.6 3 2 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY98756.1 - 0.0004 21.0 0.1 0.19 12.4 0.1 3.3 2 1 0 2 2 2 1 Aspartyl protease Spore_permease PF03845.13 ORY98758.1 - 0.31 9.8 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 Spore germination protein Herpes_BBRF1 PF04793.12 ORY98759.1 - 0.0049 16.0 0.2 0.56 9.2 0.1 2.1 2 0 0 2 2 2 2 BRRF1-like protein CBFD_NFYB_HMF PF00808.23 ORY98760.1 - 1.2e-29 102.4 0.5 1.7e-29 101.9 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY98760.1 - 2.9e-06 27.7 0.8 4.5e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY98760.1 - 0.00027 21.0 0.0 0.00042 20.4 0.0 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 ORY98760.1 - 0.0019 18.2 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 ORY98760.1 - 0.037 14.0 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-X PF09415.10 ORY98760.1 - 0.043 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pribosyltran PF00156.27 ORY98761.1 - 6.4e-13 48.5 0.2 1.7e-12 47.2 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ORY98761.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Na_H_Exchanger PF00999.21 ORY98763.1 - 1.9e-42 145.5 30.9 2.4e-42 145.1 30.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_2 PF07992.14 ORY98764.1 - 2.4e-51 174.7 0.3 2.8e-51 174.5 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY98764.1 - 1.3e-18 67.3 0.1 2.9e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY98764.1 - 3.4e-18 66.0 0.2 2.7e-15 56.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY98764.1 - 2.2e-07 30.3 0.5 0.0083 15.2 0.0 3.8 3 1 1 4 4 4 3 Glucose inhibited division protein A NAD_binding_7 PF13241.6 ORY98764.1 - 1.2e-05 25.6 0.0 0.034 14.6 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ORY98764.1 - 1.7e-05 25.0 0.5 0.0039 17.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY98764.1 - 8.3e-05 21.9 0.0 0.00077 18.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ORY98764.1 - 0.00028 20.4 0.3 0.065 12.6 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 ORY98764.1 - 0.00036 20.2 0.1 2 7.9 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY98764.1 - 0.00082 18.6 3.8 0.19 10.8 0.1 3.3 3 1 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 ORY98764.1 - 0.0022 16.8 0.7 0.11 11.2 0.1 3.4 3 1 1 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 ORY98764.1 - 0.003 16.8 0.1 0.32 10.1 0.0 2.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ORY98764.1 - 0.012 14.9 1.6 0.14 11.4 0.1 2.6 2 1 1 3 3 3 0 FAD binding domain Shikimate_DH PF01488.20 ORY98764.1 - 0.016 15.3 0.2 13 5.9 0.0 3.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 ORY98764.1 - 0.051 12.4 0.1 0.47 9.3 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase HCNGP PF07818.13 ORY98765.1 - 2.3e-29 101.9 0.1 2.3e-29 101.9 0.1 1.7 2 0 0 2 2 2 1 HCNGP-like protein Syja_N PF02383.18 ORY98766.1 - 2e-89 300.1 0.0 3.2e-89 299.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 ORY98766.1 - 1.4e-35 121.4 0.3 3.5e-35 120.2 0.0 1.7 2 0 0 2 2 2 1 Inositol phosphatase Sugar_tr PF00083.24 ORY98767.1 - 8.4e-124 413.9 18.9 9.7e-124 413.7 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY98767.1 - 3.7e-37 128.1 44.9 6.6e-31 107.5 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY98767.1 - 0.00064 18.3 0.3 0.0012 17.3 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ORY98767.1 - 0.0031 16.4 13.1 0.032 13.1 0.1 3.3 1 1 1 2 2 2 1 MFS_1 like family DUF2976 PF11190.8 ORY98767.1 - 0.13 12.1 5.0 0.14 12.0 2.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) NIF PF03031.18 ORY98768.1 - 8.1e-47 158.9 0.0 1.7e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Molybdopterin_N PF18364.1 ORY98768.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase N-terminal domain MSA-2c PF12238.8 ORY98768.1 - 0.2 11.7 4.3 0.065 13.2 0.7 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF1501 PF07394.12 ORY98768.1 - 0.94 8.5 6.3 1.5 7.8 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SurA_N_2 PF13623.6 ORY98768.1 - 2.4 8.0 8.4 2.3 8.0 6.1 2.0 2 0 0 2 2 2 0 SurA N-terminal domain DUF3391 PF11871.8 ORY98768.1 - 2.5 8.7 7.8 2.5 8.7 4.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) GBP_C PF02841.14 ORY98768.1 - 4.2 6.7 12.9 6.3 6.1 11.7 1.8 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Forkhead PF00250.18 ORY98769.1 - 8.1e-36 122.2 0.3 1.2e-35 121.6 0.3 1.2 1 0 0 1 1 1 1 Forkhead domain E1_dh PF00676.20 ORY98770.1 - 1.1e-92 310.2 0.2 1.4e-92 309.9 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORY98770.1 - 0.00071 18.9 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ORY98770.1 - 0.003 17.4 0.2 0.0077 16.0 0.2 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Img2 PF05046.14 ORY98771.1 - 9.9e-24 83.4 0.0 1.2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) GATA PF00320.27 ORY98772.1 - 7.8e-29 99.0 17.0 1.2e-15 56.8 5.3 2.8 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY98772.1 - 0.00047 19.6 3.7 0.073 12.6 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding MPM1 PF17234.2 ORY98772.1 - 0.016 15.5 0.5 0.53 10.5 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Zn-ribbon_8 PF09723.10 ORY98772.1 - 0.048 13.8 3.8 1.1 9.4 0.4 2.8 2 0 0 2 2 2 0 Zinc ribbon domain TDP43_N PF18694.1 ORY98772.1 - 0.12 12.3 0.2 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Auto_anti-p27 PF06677.12 ORY98772.1 - 0.27 11.4 7.2 1 9.6 0.8 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 ORY98772.1 - 0.29 11.0 4.7 7 6.6 0.4 2.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 ORY98772.1 - 3.1 7.8 5.4 8.7 6.4 0.6 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L32p PF01783.23 ORY98772.1 - 3.1 8.1 7.8 5.9 7.2 2.4 3.6 2 1 0 2 2 2 0 Ribosomal L32p protein family Vps36-NZF-N PF16988.5 ORY98772.1 - 3.2 7.2 6.7 30 4.1 3.1 3.6 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SUIM_assoc PF16619.5 ORY98772.1 - 4.6 7.4 22.4 21 5.2 0.5 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ABC2_membrane_3 PF12698.7 ORY98772.1 - 5 6.1 7.1 9.9 5.2 7.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein NMD3 PF04981.13 ORY98772.1 - 6 6.3 8.0 2.3 7.6 0.2 2.5 3 0 0 3 3 3 0 NMD3 family Med23 PF11573.8 ORY98773.1 - 2.4e-54 184.6 12.2 2.8e-47 161.2 0.4 2.9 3 1 0 3 3 3 2 Mediator complex subunit 23 SUIM_assoc PF16619.5 ORY98773.1 - 0.017 15.2 3.0 0.04 14.0 3.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Vir_act_alpha_C PF10400.9 ORY98773.1 - 0.079 13.7 0.3 1.2 9.8 0.1 2.6 2 0 0 2 2 2 0 Virulence activator alpha C-term Pkinase PF00069.25 ORY98774.1 - 1.8e-65 220.9 0.0 2.7e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98774.1 - 8.6e-48 162.9 0.0 1.1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98774.1 - 2.3e-07 30.4 0.1 8.8e-07 28.5 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY98774.1 - 4.5e-06 25.7 0.2 5.9e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY98774.1 - 0.00059 18.9 0.4 0.0047 15.9 0.4 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY98774.1 - 0.014 15.4 0.0 0.1 12.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY98774.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY98774.1 - 0.045 13.1 0.1 0.077 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY98774.1 - 0.11 12.1 0.2 0.3 10.7 0.1 1.7 1 1 1 2 2 2 0 RIO1 family TFIIA PF03153.13 ORY98775.1 - 1.4 8.9 15.3 1.8 8.5 15.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.33 ORY98776.1 - 4e-07 29.8 0.8 4e-07 29.8 0.8 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORY98776.1 - 5.5e-05 23.0 1.8 5.5e-05 23.0 1.8 2.2 2 0 0 2 2 2 1 F-box-like TPR_2 PF07719.17 ORY98776.1 - 0.00013 21.8 5.8 2.8 8.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98776.1 - 0.00031 21.3 5.5 0.0018 18.9 0.8 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY98776.1 - 0.00033 20.4 2.1 4.2 7.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_4 PF12799.7 ORY98776.1 - 0.00079 19.8 1.5 3.2 8.3 0.0 5.2 5 1 2 7 7 6 2 Leucine Rich repeats (2 copies) PknG_TPR PF16918.5 ORY98776.1 - 0.0086 14.8 0.1 0.018 13.8 0.1 1.6 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_9 PF13371.6 ORY98776.1 - 0.016 15.4 2.2 0.39 10.9 2.5 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ORY98776.1 - 0.025 15.0 0.2 0.081 13.4 0.1 1.8 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_14 PF13428.6 ORY98776.1 - 0.043 14.6 3.9 0.8 10.7 2.0 3.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY98776.1 - 0.06 13.9 2.5 1.4 9.5 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98776.1 - 0.068 13.4 1.5 9.8 6.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 ORY98776.1 - 0.13 12.4 3.9 0.89 9.8 0.0 3.9 4 0 0 4 4 3 0 Leucine Rich repeat TPR_12 PF13424.6 ORY98776.1 - 0.23 11.8 3.1 0.75 10.1 0.8 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_1 PF00560.33 ORY98776.1 - 1.4 9.7 5.4 9.3 7.3 0.0 4.4 5 0 0 5 5 3 0 Leucine Rich Repeat Spt20 PF12090.8 ORY98777.1 - 0.022 14.4 9.7 0.024 14.3 9.7 1.1 1 0 0 1 1 1 0 Spt20 family PH_4 PF15404.6 ORY98777.1 - 0.03 14.1 0.2 0.04 13.7 0.2 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIA PF03153.13 ORY98777.1 - 0.047 13.7 7.5 0.046 13.7 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 ORY98777.1 - 0.13 11.0 7.6 0.15 10.9 7.6 1.1 1 0 0 1 1 1 0 Androgen receptor Cyclin_N PF00134.23 ORY98778.1 - 1.3e-19 70.2 1.0 1.9e-19 69.6 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY98778.1 - 0.0008 19.4 1.2 0.0027 17.7 0.1 2.3 2 1 0 2 2 2 1 Transcription factor TFIIB repeat pPIWI_RE_Y PF18156.1 ORY98778.1 - 0.048 14.1 0.1 0.081 13.3 0.1 1.5 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y RAI16-like PF10257.9 ORY98779.1 - 8.4e-67 225.6 0.1 1.4e-66 224.8 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DGF-1_C PF11040.8 ORY98779.1 - 0.35 10.9 2.0 1 9.4 0.2 2.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus GIT_SHD PF08518.11 ORY98780.1 - 3e-19 68.3 1.8 4.1e-12 45.5 0.2 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 ORY98780.1 - 2.5e-06 27.6 11.2 1.7e-05 24.9 0.0 3.8 3 1 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term ApoLp-III PF07464.11 ORY98780.1 - 0.029 14.5 5.5 0.056 13.5 1.8 3.1 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.11 ORY98780.1 - 0.04 12.8 18.5 0.035 13.0 13.7 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 ORY98780.1 - 0.21 11.8 23.1 0.072 13.3 16.0 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ERM PF00769.19 ORY98780.1 - 0.26 11.0 21.1 0.18 11.6 18.0 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ZapB PF06005.12 ORY98780.1 - 0.4 11.2 23.8 8.7 6.9 18.7 3.8 3 1 0 3 3 3 0 Cell division protein ZapB SlyX PF04102.12 ORY98780.1 - 0.55 10.9 12.8 1.2 9.8 9.8 3.0 1 1 1 2 2 2 0 SlyX CALCOCO1 PF07888.11 ORY98780.1 - 0.72 8.6 24.7 1.2 7.9 24.7 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-H PF05837.12 ORY98780.1 - 1.5 9.3 17.1 1.3 9.5 12.6 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 ORY98780.1 - 2 6.2 9.8 2.9 5.7 9.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.9 ORY98780.1 - 3.2 8.0 17.6 0.73 10.1 2.8 2.7 1 1 1 2 2 2 0 Zinc finger-containing protein IFT20 PF14931.6 ORY98780.1 - 4.5 7.5 17.2 2.2 8.5 3.5 3.3 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF724 PF05266.14 ORY98780.1 - 4.7 7.0 16.6 0.42 10.4 11.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HAUS6_N PF14661.6 ORY98780.1 - 5 6.6 14.1 28 4.2 0.0 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 ORY98780.1 - 5.7 5.4 8.1 11 4.5 8.1 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_F PF12259.8 ORY98780.1 - 6.3 5.2 8.8 1.1 7.7 5.0 1.5 2 0 0 2 2 2 0 Baculovirus F protein JIP_LZII PF16471.5 ORY98780.1 - 6.4 7.0 12.2 11 6.3 5.5 3.0 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 ORY98780.1 - 6.5 6.0 14.6 0.3 10.4 8.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF573 PF04504.14 ORY98780.1 - 9.1 7.0 9.3 0.88 10.3 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 ANAPC8 PF04049.13 ORY98781.1 - 2.9e-34 118.1 1.1 8.9e-34 116.5 1.1 1.9 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 ORY98781.1 - 1.8e-19 68.7 21.4 1.2e-05 24.9 0.1 8.0 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98781.1 - 1.4e-17 62.3 27.1 5.3e-05 23.1 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY98781.1 - 1.6e-15 55.8 33.0 8.1e-05 22.4 0.1 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY98781.1 - 3.8e-15 55.3 6.8 4.2e-08 32.7 0.6 4.2 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.6 ORY98781.1 - 1.1e-14 53.9 17.1 0.00025 21.6 0.1 8.1 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY98781.1 - 7.6e-12 45.6 14.9 0.00057 20.3 0.1 5.8 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98781.1 - 2.2e-09 37.8 18.7 1.4e-06 28.8 0.1 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY98781.1 - 5.4e-08 32.7 10.4 0.013 15.8 0.2 5.9 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY98781.1 - 1.1e-07 31.4 16.8 0.51 10.5 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY98781.1 - 8.4e-06 25.9 32.5 0.00035 20.7 0.8 6.5 5 1 4 9 9 8 5 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 ORY98781.1 - 1.2e-05 24.5 0.2 0.0021 17.2 0.0 3.1 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 ORY98781.1 - 0.0017 18.6 28.3 0.26 11.6 1.7 7.1 5 1 2 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY98781.1 - 0.0029 17.7 0.3 0.0029 17.7 0.3 3.3 3 1 1 4 4 3 1 Tetratricopeptide repeat Amidase_2 PF01510.25 ORY98781.1 - 0.034 14.6 0.1 0.074 13.5 0.1 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase TPR_10 PF13374.6 ORY98781.1 - 0.12 12.3 11.1 18 5.3 0.0 5.8 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY98781.1 - 2.7 8.8 0.0 2.7 8.8 0.0 6.9 8 1 0 8 8 8 0 Tetratricopeptide repeat Tfb5 PF06331.12 ORY98782.1 - 2.1e-26 91.7 0.9 2.5e-26 91.4 0.9 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Transketolase_N PF00456.21 ORY98784.1 - 5.6e-145 482.5 0.0 7.3e-145 482.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY98784.1 - 2.7e-40 137.9 0.0 7.1e-40 136.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY98784.1 - 3.6e-12 46.3 0.1 3.5e-11 43.1 0.1 2.4 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY98784.1 - 0.0033 16.7 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ORY98784.1 - 0.034 13.1 0.0 0.067 12.1 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Beta_elim_lyase PF01212.21 ORY98784.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF1143 PF06608.11 ORY98784.1 - 0.21 11.6 0.4 0.57 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) Ribosomal_L35Ae PF01247.18 ORY98785.1 - 1.2e-41 140.8 0.8 1.3e-41 140.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY98785.1 - 0.00014 22.0 0.1 0.54 10.5 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain RNA_pol PF00940.19 ORY98786.1 - 6.6e-184 611.5 0.0 1.2e-183 610.7 0.0 1.5 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 ORY98786.1 - 9.1e-95 317.9 0.3 1.9e-94 316.8 0.3 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 ORY98786.1 - 1.6e-08 34.6 2.4 5.6e-05 23.2 0.1 3.4 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.20 ORY98786.1 - 0.00023 21.2 1.3 2.8 8.4 0.0 4.0 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 ORY98786.1 - 0.00056 19.9 0.4 1 9.5 0.0 3.1 1 1 2 3 3 3 3 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY98786.1 - 0.018 14.4 0.1 0.081 12.3 0.1 1.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY98786.1 - 0.054 13.2 2.2 3.4 7.4 0.0 3.5 4 0 0 4 4 4 0 PPR repeat Thioredoxin PF00085.20 ORY98788.1 - 1.7e-67 223.9 5.6 7.9e-34 115.8 0.1 4.4 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 ORY98788.1 - 1.5e-43 148.9 3.0 2.2e-29 102.7 0.4 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 ORY98788.1 - 2.1e-11 44.2 1.6 0.00012 22.5 0.0 4.1 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY98788.1 - 9.1e-10 38.7 0.2 1.3 9.4 0.1 5.5 4 2 1 5 5 5 3 Thioredoxin-like Thioredoxin_7 PF13899.6 ORY98788.1 - 1.9e-07 31.1 0.0 0.046 13.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 ORY98788.1 - 2.3e-07 30.5 0.0 0.0046 16.4 0.0 2.6 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 ORY98788.1 - 2.9e-05 23.3 9.6 0.0001 21.5 4.5 3.0 3 0 0 3 3 3 1 Calsequestrin ERp29_N PF07912.13 ORY98788.1 - 9.3e-05 22.6 1.6 0.48 10.6 0.0 3.8 3 1 1 4 4 4 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 ORY98788.1 - 0.00018 21.5 0.2 0.37 10.9 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_5 PF13743.6 ORY98788.1 - 0.00066 19.4 0.3 1 9.0 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin AhpC-TSA PF00578.21 ORY98788.1 - 0.0018 18.2 1.0 0.57 10.1 0.0 3.3 3 0 0 3 3 3 1 AhpC/TSA family HyaE PF07449.11 ORY98788.1 - 0.042 13.8 0.0 26 4.8 0.0 3.5 3 1 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Miga PF10265.9 ORY98789.1 - 4.4 6.2 10.3 0.27 10.1 4.1 1.8 1 1 1 2 2 2 0 Mitoguardin CTP_transf_like PF01467.26 ORY98790.1 - 5.9e-45 153.0 0.0 2.9e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 ORY98790.1 - 0.00047 20.1 0.4 1.4 8.7 0.0 2.8 3 0 0 3 3 3 2 FAD synthetase ScdA_N PF04405.14 ORY98790.1 - 0.0039 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown function (DUF542) Pantoate_ligase PF02569.15 ORY98790.1 - 0.056 12.7 0.1 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Pkinase PF00069.25 ORY98791.1 - 7.9e-52 176.2 0.2 1.5e-51 175.3 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98791.1 - 2.6e-20 72.8 0.1 8.2e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ORY98791.1 - 0.012 14.9 0.2 0.023 14.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 ORY98792.1 - 3.5e-25 89.1 0.0 6.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY98792.1 - 1.7e-08 34.7 0.1 0.00029 20.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY98792.1 - 0.0002 20.9 0.0 0.0057 16.1 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ORY98792.1 - 0.00052 19.8 0.0 0.0016 18.2 0.0 1.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 ORY98792.1 - 0.0006 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ORY98792.1 - 0.00093 19.2 0.1 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 ORY98792.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY98792.1 - 0.0038 17.5 0.3 0.0075 16.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORY98792.1 - 0.0039 16.6 0.0 0.058 12.8 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 ORY98792.1 - 0.0066 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ORY98792.1 - 0.0068 16.9 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ORY98792.1 - 0.0072 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 ORY98792.1 - 0.0095 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 ORY98792.1 - 0.011 16.3 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY98792.1 - 0.017 15.3 0.3 0.035 14.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 ORY98792.1 - 0.034 14.6 0.1 0.23 11.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 ORY98792.1 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 ORY98792.1 - 0.046 14.0 0.1 1 9.6 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 ORY98792.1 - 0.052 13.5 0.1 0.39 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ORY98792.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CBM39 PF15886.5 ORY98792.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) AAA_25 PF13481.6 ORY98792.1 - 0.098 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY98792.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY98792.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY98792.1 - 0.15 12.4 0.0 0.54 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY98792.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.6 ORY98793.1 - 1.6e-09 37.7 6.0 9.9e-07 28.9 0.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY98793.1 - 1.8e-08 34.4 9.3 1.7e-05 25.0 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY98793.1 - 3.9e-07 30.4 7.6 0.0012 19.5 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY98793.1 - 0.00017 21.3 3.6 0.046 13.5 0.3 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORY98793.1 - 0.0025 18.1 4.8 0.03 14.7 1.4 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY98793.1 - 0.0072 16.6 1.2 2.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORY98793.1 - 0.049 13.4 0.8 0.049 13.4 0.8 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 ORY98793.1 - 0.22 11.5 6.5 2.6 8.0 1.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Metallophos PF00149.28 ORY98794.1 - 1.7e-37 129.9 0.2 3.1e-37 129.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY98794.1 - 2.1e-15 56.9 0.1 4.1e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain ALMT PF11744.8 ORY98794.1 - 6.1 5.6 5.7 7.8 5.2 5.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ysc84 PF04366.12 ORY98795.1 - 5.1e-34 116.8 1.0 7.2e-34 116.3 0.1 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORY98795.1 - 1.1e-12 47.3 0.0 2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY98795.1 - 5.3e-12 45.4 0.1 9.3e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY98795.1 - 5.3e-09 35.6 0.1 1.1e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2207 PF09972.9 ORY98796.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ENTH PF01417.20 ORY98797.1 - 1e-46 158.1 0.1 7.4e-46 155.3 0.0 2.1 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 ORY98797.1 - 2.9e-06 26.5 0.0 4.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 ORY98797.1 - 3.5e-06 26.5 8.2 0.02 14.8 0.3 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF1720 PF08226.11 ORY98797.1 - 0.51 10.8 108.9 1.8e+04 -6.9 30.2 5.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1720) WD40 PF00400.32 ORY98798.1 - 4e-09 37.0 1.5 5.5e-06 27.0 0.1 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY98798.1 - 0.0017 18.6 0.0 2.4 8.5 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY98798.1 - 0.1 11.1 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nup160 PF11715.8 ORY98798.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NUDIX_2 PF13869.6 ORY98799.1 - 1.6e-78 262.6 0.1 1.8e-78 262.5 0.1 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UCR_14kD PF02271.16 ORY98799.1 - 0.1 12.6 0.1 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit WD40 PF00400.32 ORY98800.1 - 4.3e-17 62.2 8.2 0.0083 17.0 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY98800.1 - 8e-07 29.3 2.9 0.0011 19.2 0.8 4.1 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY98800.1 - 1e-06 27.7 0.9 3.3e-05 22.7 0.7 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 BBS2_N PF14781.6 ORY98800.1 - 0.043 13.7 0.0 10 6.1 0.0 3.4 2 2 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Ge1_WD40 PF16529.5 ORY98800.1 - 0.05 12.5 2.3 4.9 6.0 0.0 3.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 ORY98800.1 - 0.13 12.8 1.4 30 5.3 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain DUF2368 PF10166.9 ORY98800.1 - 0.13 11.9 0.4 0.26 10.9 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Acetyltransf_1 PF00583.25 ORY98801.1 - 7.3e-13 48.8 0.0 8.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY98801.1 - 6.2e-09 35.9 0.0 8.9e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY98801.1 - 5.3e-07 30.0 0.0 6.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY98801.1 - 2.1e-06 27.6 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY98801.1 - 4.3e-05 23.6 0.0 0.00016 21.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY98801.1 - 0.045 14.4 0.0 0.095 13.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY98801.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3684 PF12449.8 ORY98802.1 - 0 1015.6 0.3 8.1e-297 987.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3684) DUF4279 PF14106.6 ORY98802.1 - 0.072 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) WLM PF08325.10 ORY98802.1 - 0.34 10.9 2.3 0.69 10.0 2.3 1.4 1 0 0 1 1 1 0 WLM domain HMGL-like PF00682.19 ORY98803.1 - 0.0063 16.1 0.2 0.0076 15.8 0.2 1.1 1 0 0 1 1 1 1 HMGL-like Mur_ligase_M PF08245.12 ORY98803.1 - 0.013 15.5 0.0 0.043 13.8 0.0 1.8 1 1 0 1 1 1 0 Mur ligase middle domain DMRL_synthase PF00885.19 ORY98804.1 - 1.3e-51 174.2 0.1 1.5e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase U-box PF04564.15 ORY98805.1 - 2.1e-21 75.9 0.0 4.6e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.6 ORY98805.1 - 2e-09 37.0 1.2 0.0026 17.4 0.1 4.0 4 1 1 5 5 5 2 TPR repeat CHIP_TPR_N PF18391.1 ORY98805.1 - 2.6e-09 37.7 5.9 2.6e-09 37.7 5.9 2.7 2 1 1 3 3 3 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 ORY98805.1 - 1.1e-08 34.6 5.7 0.0039 17.2 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY98805.1 - 9.5e-08 31.6 4.2 0.12 12.2 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98805.1 - 0.00016 22.3 0.0 0.92 10.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 ORY98805.1 - 0.00019 21.5 0.0 0.00081 19.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_14 PF13428.6 ORY98805.1 - 0.0026 18.4 1.5 2.7 9.0 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY98805.1 - 0.0072 16.8 0.3 0.26 11.8 0.3 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY98805.1 - 0.012 15.8 1.0 0.035 14.3 0.1 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 ORY98805.1 - 0.039 14.3 0.0 0.18 12.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY98805.1 - 0.067 13.5 3.0 0.53 10.6 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98805.1 - 0.093 13.0 5.6 0.37 11.1 0.5 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY98805.1 - 0.099 13.0 3.3 3.1 8.2 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1899 PF08953.11 ORY98806.1 - 1.7e-32 111.1 0.1 3.1e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 ORY98806.1 - 7e-22 77.1 0.5 1.4e-21 76.1 0.5 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 ORY98806.1 - 1e-19 70.5 0.1 0.0003 21.5 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY98806.1 - 2.2e-08 34.3 0.1 0.00016 21.9 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY98806.1 - 0.18 10.5 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like DUF4611 PF15387.6 ORY98807.1 - 2.6e-08 34.0 3.3 2.9e-08 33.8 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Gon7 PF08738.10 ORY98807.1 - 3.1e-08 33.6 4.3 6.9e-08 32.5 1.0 2.4 1 1 0 1 1 1 1 Gon7 family Sporozoite_P67 PF05642.11 ORY98807.1 - 0.099 10.7 5.1 0.092 10.8 5.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 ORY98807.1 - 0.36 10.1 4.0 0.35 10.1 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ORY98807.1 - 4.5 5.3 8.0 4.8 5.2 8.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 ORY98807.1 - 4.7 5.4 7.2 5.1 5.3 7.2 1.0 1 0 0 1 1 1 0 CDC45-like protein SWIM PF04434.17 ORY98808.1 - 0.016 14.8 1.7 0.016 14.8 1.7 1.8 2 1 0 2 2 2 0 SWIM zinc finger DPBB_1 PF03330.18 ORY98809.1 - 2.2e-06 27.8 0.1 4.4e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY98809.1 - 0.0041 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Barwin family PAS PF00989.25 ORY98810.1 - 0.005 16.8 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 ORY98810.1 - 0.0061 16.7 6.6 0.0061 16.7 6.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.23 ORY98812.1 - 3e-94 315.2 0.9 4.8e-94 314.5 0.9 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY98812.1 - 3.8e-42 142.8 0.7 3.8e-42 142.8 0.7 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY98812.1 - 3.3e-07 30.2 0.3 3.3e-07 30.2 0.3 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY98812.1 - 0.13 12.1 3.6 4.6 7.2 0.3 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Otopetrin PF03189.13 ORY98813.1 - 4.1 6.1 12.9 0.42 9.4 2.0 2.1 1 1 1 2 2 2 0 Otopetrin L51_S25_CI-B8 PF05047.16 ORY98814.1 - 1.9e-11 43.7 0.3 3.4e-11 42.9 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SnoaL_2 PF12680.7 ORY98815.1 - 0.0072 16.9 0.4 0.018 15.7 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 ORY98815.1 - 0.21 11.4 1.0 0.62 9.9 0.0 2.3 2 1 0 2 2 2 0 SnoaL-like polyketide cyclase CUE PF02845.16 ORY98816.1 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 ORY98816.1 - 0.0014 18.5 0.3 0.0021 17.9 0.3 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 ORY98816.1 - 0.12 12.4 5.5 0.2 11.7 5.5 1.3 1 0 0 1 1 1 0 Rhomboid family Retinal PF15449.6 ORY98816.1 - 0.73 7.6 8.5 0.91 7.2 8.5 1.0 1 0 0 1 1 1 0 Retinal protein GCIP PF13324.6 ORY98817.1 - 4.2e-22 79.0 0.7 9.5e-22 77.8 0.7 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting Laminin_II PF06009.12 ORY98817.1 - 0.0053 16.8 2.4 0.15 12.1 0.1 2.5 1 1 1 2 2 2 1 Laminin Domain II SesA PF17107.5 ORY98817.1 - 0.0054 16.9 0.7 0.0054 16.9 0.7 3.2 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ATG_C PF09333.11 ORY98817.1 - 0.098 13.0 0.3 1.9 8.9 0.0 2.8 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain DUF948 PF06103.11 ORY98817.1 - 0.19 12.0 5.8 3.8 7.8 2.8 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mog1 PF04603.12 ORY98817.1 - 0.29 11.5 6.1 0.13 12.6 1.3 2.4 3 0 0 3 3 3 0 Ran-interacting Mog1 protein DASH_Dam1 PF08653.10 ORY98818.1 - 5.5e-11 42.1 0.4 1.1e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 FmiP_Thoc5 PF09766.9 ORY98818.1 - 0.66 9.2 5.1 12 5.1 5.1 2.4 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 Med21 PF11221.8 ORY98818.1 - 0.85 9.9 5.8 0.39 11.0 2.9 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DER1 PF04511.15 ORY98819.1 - 5.2e-51 173.3 7.4 6.1e-51 173.1 7.4 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 ORY98819.1 - 0.018 15.0 7.5 0.054 13.5 7.6 1.8 1 1 0 1 1 1 0 Rhomboid family Spo7 PF03907.13 ORY98820.1 - 2.5e-22 79.4 9.4 1.7e-20 73.5 3.2 2.1 1 1 1 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.9 ORY98820.1 - 4.8e-06 27.0 0.2 7e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 188 DUF2614 PF11023.8 ORY98820.1 - 0.025 14.7 0.4 0.034 14.2 0.4 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Peptidase_M24 PF00557.24 ORY98821.1 - 7.8e-54 182.5 0.1 9.6e-54 182.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORY98821.1 - 3.6e-16 59.2 12.7 9.2e-16 57.9 12.7 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 ORY98821.1 - 0.17 11.8 4.0 0.42 10.5 4.0 1.7 1 0 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 ORY98821.1 - 0.18 12.0 10.8 0.38 10.9 10.8 1.6 1 0 0 1 1 1 0 MYND finger NDUFB10 PF10249.9 ORY98822.1 - 1.4e-10 41.8 1.2 1.6e-10 41.5 1.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 TRAM_LAG1_CLN8 PF03798.16 ORY98826.1 - 2.7e-38 131.7 19.9 2.7e-38 131.7 19.9 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORY98826.1 - 2.7e-13 49.4 0.1 8.9e-13 47.7 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein Phosphoesterase PF04185.14 ORY98827.1 - 1.8e-55 188.6 0.3 4e-55 187.5 0.3 1.5 1 1 0 1 1 1 1 Phosphoesterase family GCS PF03074.16 ORY98828.1 - 5.9e-181 601.7 0.0 8.3e-181 601.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase S1 PF00575.23 ORY98828.1 - 0.05 14.0 0.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 S1 RNA binding domain Pex16 PF08610.10 ORY98829.1 - 2.3e-60 204.5 0.1 5.3e-60 203.3 0.1 1.5 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF805 PF05656.14 ORY98829.1 - 0.068 13.6 0.2 0.43 11.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF805) zf-C2H2 PF00096.26 ORY98830.1 - 5.6e-12 45.4 22.4 5.5e-07 29.7 0.3 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY98830.1 - 3e-09 36.9 19.0 4.4e-06 26.9 1.4 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY98830.1 - 6e-06 26.7 19.4 0.00033 21.2 0.3 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf_ZIC PF18366.1 ORY98830.1 - 0.00017 21.6 5.1 0.014 15.5 0.1 3.5 2 1 1 3 3 3 2 Zic proteins zinc finger domain FOXP-CC PF16159.5 ORY98830.1 - 0.021 15.5 13.8 2.9 8.6 0.1 4.1 2 1 3 5 5 5 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORY98830.1 - 0.055 13.5 0.1 0.055 13.5 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-TAZ PF02135.16 ORY98830.1 - 0.074 13.5 7.7 0.094 13.2 2.2 2.4 1 1 1 2 2 2 0 TAZ zinc finger zf-C2H2_jaz PF12171.8 ORY98830.1 - 2.2 8.7 0.0 2.2 8.7 0.0 3.5 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY98830.1 - 2.5 8.2 7.0 6.9 6.8 0.1 3.0 1 1 2 3 3 3 0 Aberrant zinc-finger NAD_binding_6 PF08030.12 ORY98831.1 - 9.5e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY98831.1 - 1.2e-12 48.1 6.3 1.2e-12 48.1 6.3 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY98831.1 - 4.8e-12 45.9 0.0 9.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY98831.1 - 0.0062 17.2 0.0 0.044 14.4 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY98831.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain CRAL_TRIO PF00650.20 ORY98832.1 - 1.6e-32 112.5 0.0 2.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY98832.1 - 4.1e-06 26.9 0.1 4.1e-06 26.9 0.1 2.4 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain AAL_decarboxy PF03306.13 ORY98832.1 - 0.028 13.8 0.4 0.06 12.7 0.4 1.5 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase CRAL_TRIO_2 PF13716.6 ORY98832.1 - 0.14 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain SnoaL PF07366.12 ORY98833.1 - 0.059 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase S4 PF01479.25 ORY98834.1 - 1.1e-11 44.3 0.0 2.6e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 ORY98834.1 - 2.1e-11 44.6 1.8 3.6e-11 43.8 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF2157 PF09925.9 ORY98836.1 - 0.037 13.8 0.1 11 5.8 0.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3671 PF12420.8 ORY98836.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function BatA PF07584.11 ORY98836.1 - 1.3 9.4 3.4 8 6.9 3.4 2.3 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal Rad9 PF04139.13 ORY98837.1 - 7.5e-38 130.4 0.1 8.9e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 Rad9 MFS_1 PF07690.16 ORY98838.1 - 1.5e-44 152.4 42.4 3.6e-41 141.3 23.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 ORY98838.1 - 10 6.6 13.4 0.95 9.8 1.0 4.3 2 2 2 4 4 4 0 Phage holin family Hol44, in holin superfamily V Rpp20 PF12328.8 ORY98839.1 - 2.4e-10 40.5 1.0 1.2e-06 28.5 0.1 2.0 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 ORY98839.1 - 1.2e-09 37.9 0.1 1.4e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Alba SpoVS PF04232.12 ORY98839.1 - 0.032 13.9 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) DUF1192 PF06698.11 ORY98840.1 - 0.014 15.4 0.8 0.029 14.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) BRCC36_C PF18110.1 ORY98840.1 - 0.03 14.5 0.4 0.045 13.9 0.4 1.4 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain LURAP PF14854.6 ORY98840.1 - 0.16 11.9 1.9 0.24 11.4 1.6 1.5 1 1 0 1 1 1 0 Leucine rich adaptor protein LTXXQ PF07813.12 ORY98842.1 - 0.02 15.6 1.8 0.02 15.6 1.8 1.9 2 0 0 2 2 2 0 LTXXQ motif family protein Tmemb_cc2 PF10267.9 ORY98842.1 - 0.023 13.9 2.2 0.029 13.5 2.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Miga PF10265.9 ORY98842.1 - 0.73 8.7 4.7 0.91 8.4 4.7 1.1 1 0 0 1 1 1 0 Mitoguardin SPX PF03105.19 ORY98842.1 - 0.99 9.3 13.4 1.3 8.9 13.4 1.1 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 ORY98843.1 - 6.6e-53 179.8 0.0 8.3e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98843.1 - 1.6e-27 96.4 0.0 2e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98843.1 - 7.1e-11 41.9 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY98843.1 - 7.5e-06 25.0 0.0 7.8e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY98843.1 - 0.0017 17.3 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY98843.1 - 0.0019 17.6 0.2 0.0038 16.6 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY98843.1 - 0.0021 18.0 0.2 0.087 12.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY98843.1 - 0.0085 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 ORY98843.1 - 0.0088 15.7 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 ORY98843.1 - 0.017 14.8 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ORY98844.1 - 1.2e-76 257.5 0.0 1.4e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98844.1 - 4.8e-37 127.6 0.0 6.8e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY98844.1 - 0.0002 20.8 0.1 0.00028 20.3 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY98844.1 - 0.00027 20.0 0.0 0.0028 16.7 0.0 2.2 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORY98844.1 - 0.073 13.0 0.1 0.25 11.2 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY98844.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORY98844.1 - 0.15 11.4 0.6 0.44 9.9 0.6 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_2 PF07716.15 ORY98845.1 - 3.5e-09 36.6 14.8 3.9e-08 33.3 10.0 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORY98845.1 - 1.2e-08 34.9 8.3 2.1e-08 34.1 8.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor KASH_CCD PF14662.6 ORY98845.1 - 0.0055 16.6 1.6 0.0055 16.6 1.6 1.6 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH bZIP_Maf PF03131.17 ORY98845.1 - 0.019 15.4 11.3 0.046 14.2 11.3 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor SR-25 PF10500.9 ORY98845.1 - 0.023 14.3 9.9 0.028 14.0 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein T3SS_basalb_I PF17001.5 ORY98845.1 - 0.061 13.9 4.2 0.16 12.5 3.2 1.9 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI FapA PF03961.13 ORY98845.1 - 0.074 11.6 1.7 0.083 11.5 1.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 ORY98845.1 - 0.13 12.3 11.5 0.25 11.4 11.5 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 ORY98845.1 - 0.18 12.1 1.8 1.9 8.8 0.8 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family Dsh_C PF12316.8 ORY98845.1 - 0.2 12.1 6.8 0.2 12.0 6.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal ZapB PF06005.12 ORY98845.1 - 0.63 10.5 8.7 0.26 11.8 5.6 1.8 1 1 1 2 2 2 0 Cell division protein ZapB Macoilin PF09726.9 ORY98845.1 - 1.6 7.2 9.8 2.2 6.7 9.8 1.2 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 ORY98845.1 - 4.5 6.9 14.0 14 5.3 0.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 pPIWI_RE_Z PF18155.1 ORY98846.1 - 0.022 14.6 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z CDC45 PF02724.14 ORY98846.1 - 0.18 10.1 8.8 0.18 10.0 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ORY98846.1 - 0.21 10.8 13.2 0.29 10.4 13.2 1.2 1 0 0 1 1 1 0 NOA36 protein FAM60A PF15396.6 ORY98846.1 - 1.1 9.2 6.5 1.5 8.8 6.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A BPL_N PF09825.9 ORY98846.1 - 3.8 6.5 7.2 4.6 6.2 7.2 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FSA_C PF10479.9 ORY98847.1 - 0.067 11.3 0.7 0.068 11.3 0.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RRM_1 PF00076.22 ORY98847.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3439 PF11921.8 ORY98847.1 - 1.9 8.5 5.8 2.9 7.9 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SPX PF03105.19 ORY98848.1 - 1.3 8.9 12.1 2.3 8.1 12.1 1.5 1 1 0 1 1 1 0 SPX domain Velvet PF11754.8 ORY98850.1 - 5.9e-70 236.0 0.0 5.9e-70 236.0 0.0 3.9 2 1 0 2 2 2 1 Velvet factor Myosin_tail_1 PF01576.19 ORY98850.1 - 0.18 9.6 1.6 0.25 9.1 1.6 1.1 1 0 0 1 1 1 0 Myosin tail ABC1 PF03109.16 ORY98851.1 - 1.4e-21 76.9 0.1 8e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 ORY98851.1 - 0.022 14.4 0.2 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 ORY98851.1 - 0.19 11.1 0.9 8.9 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.23 ORY98851.1 - 0.5 10.2 3.1 1.6 8.6 0.1 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.27 ORY98852.1 - 1.6e-42 144.9 0.0 3.8e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY98852.1 - 7.5e-16 58.5 0.0 1.8e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 ORY98852.1 - 7.9e-11 41.9 0.0 2.4e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 ORY98852.1 - 1.9e-07 31.5 0.0 9.8e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 ORY98852.1 - 0.002 18.4 0.1 0.0067 16.7 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain TolA_bind_tri PF16331.5 ORY98852.1 - 0.081 13.0 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1952 PF09189.10 ORY98852.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) Plus-3 PF03126.18 ORY98853.1 - 4.1e-31 107.7 0.1 1.3e-30 106.1 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain Nop PF01798.18 ORY98854.1 - 9.4e-86 287.0 0.3 1.3e-85 286.5 0.3 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORY98854.1 - 4.6e-21 75.0 0.7 4.6e-21 75.0 0.7 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain EF-hand_8 PF13833.6 ORY98854.1 - 0.0089 15.9 0.4 0.82 9.6 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair ANAPC4 PF12896.7 ORY98854.1 - 0.096 12.2 0.1 0.88 9.0 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 Top6b_C PF18000.1 ORY98854.1 - 0.13 12.5 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Na_H_Exchanger PF00999.21 ORY98855.1 - 2.6e-56 191.1 26.6 3.5e-56 190.6 26.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CstA PF02554.14 ORY98855.1 - 0.00093 18.2 6.5 0.00093 18.2 6.5 2.3 2 0 0 2 2 2 1 Carbon starvation protein CstA RabGAP-TBC PF00566.18 ORY98856.1 - 4e-45 154.1 0.1 8.2e-45 153.1 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CRC_subunit PF08624.10 ORY98857.1 - 1.5e-43 148.4 0.3 2.4e-42 144.6 0.1 2.1 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Requiem_N PF14051.6 ORY98857.1 - 0.086 13.0 0.1 0.086 13.0 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain of DPF2/REQ. Aminotran_5 PF00266.19 ORY98858.1 - 2.6e-94 316.2 0.0 3.1e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY98858.1 - 4e-06 26.3 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY98858.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 ORY98858.1 - 0.0014 17.4 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain 4_1_CTD PF05902.13 ORY98858.1 - 0.03 14.4 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) DUF3217 PF11506.8 ORY98858.1 - 0.059 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) Ribosomal_S24e PF01282.19 ORY98858.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S24e PH PF00169.29 ORY98859.1 - 0.00021 21.7 0.0 0.00068 20.1 0.0 1.9 1 1 0 1 1 1 1 PH domain DUF713 PF05218.14 ORY98859.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF713) DUF5098 PF17023.5 ORY98859.1 - 0.13 11.2 0.5 0.73 8.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5098) Histone PF00125.24 ORY98860.1 - 1.9e-23 83.3 0.5 2.3e-23 83.0 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY98860.1 - 1.8e-06 28.2 1.0 3.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY98860.1 - 0.00033 21.1 0.0 0.00064 20.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 ORY98860.1 - 0.0052 17.0 0.0 0.0074 16.5 0.0 1.3 1 0 0 1 1 1 1 CENP-W protein RP-C PF03428.13 ORY98860.1 - 0.04 13.6 0.2 0.13 11.9 0.2 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain CENP-T_C PF15511.6 ORY98860.1 - 0.079 13.1 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Histone_H2A_C PF16211.5 ORY98861.1 - 7.7e-21 73.5 1.4 1.4e-20 72.7 1.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY98861.1 - 1.2e-16 61.3 0.0 1.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY98861.1 - 7.6e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 ORY98862.1 - 2.6e-08 33.9 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY98862.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY98862.1 - 9.7e-05 22.7 0.1 0.00013 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY98862.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY98862.1 - 0.00035 20.8 0.1 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY98862.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY98862.1 - 0.059 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY98862.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 ORY98863.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY98863.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY98863.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY98863.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY98863.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY98863.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY98863.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone_H2A_C PF16211.5 ORY98864.1 - 7.7e-21 73.5 1.4 1.4e-20 72.7 1.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY98864.1 - 1.2e-16 61.3 0.0 1.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY98864.1 - 7.6e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY98865.1 - 3.3e-23 82.5 0.5 4.4e-23 82.1 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY98865.1 - 1.2e-06 28.7 0.0 2.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY98865.1 - 0.00025 21.5 0.0 0.0005 20.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 ORY98865.1 - 0.0041 17.3 0.0 0.0058 16.8 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein RP-C PF03428.13 ORY98865.1 - 0.024 14.3 0.2 0.095 12.3 0.2 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain CENP-T_C PF15511.6 ORY98865.1 - 0.062 13.4 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold RRM_1 PF00076.22 ORY98866.1 - 5.5e-15 54.9 0.0 6.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-ribbon_3 PF13248.6 ORY98866.1 - 0.054 12.9 1.4 0.086 12.3 1.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-RanBP PF00641.18 ORY98866.1 - 0.55 9.6 3.2 1.1 8.6 3.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Arrestin_C PF02752.22 ORY98867.1 - 7e-05 23.3 0.1 0.00015 22.2 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain YCII PF03795.14 ORY98868.1 - 4.4e-08 33.4 0.0 5.7e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain ESCRT-II PF05871.12 ORY98869.1 - 8.8e-51 171.8 0.8 1e-50 171.6 0.8 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sds3 PF08598.11 ORY98870.1 - 2.5e-13 50.6 3.7 2.5e-13 50.6 3.7 2.8 1 1 1 2 2 2 1 Sds3-like DUF1843 PF08898.10 ORY98870.1 - 0.0052 17.2 0.4 2 9.0 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF1843) Cofilin_ADF PF00241.20 ORY98871.1 - 3.6e-43 146.2 1.5 4.1e-43 146.0 1.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Sin3a_C PF16879.5 ORY98872.1 - 5.7e-42 144.4 1.1 1.1e-41 143.5 0.3 2.0 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 ORY98872.1 - 4e-29 100.6 0.0 1.1e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 ORY98872.1 - 1.9e-15 56.7 14.6 8.3e-09 35.5 0.3 4.7 4 1 0 4 4 4 3 Paired amphipathic helix repeat Xpo1 PF08389.12 ORY98872.1 - 0.2 11.7 1.1 20 5.2 0.0 3.4 3 0 0 3 3 3 0 Exportin 1-like protein Tom37 PF10568.9 ORY98873.1 - 1.1e-33 116.1 0.5 2.1e-33 115.3 0.5 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 ORY98873.1 - 1.2e-21 77.3 0.0 2.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ORY98873.1 - 5.1e-20 71.0 0.1 1.2e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY98873.1 - 5.2e-08 32.8 0.2 1.5e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY98873.1 - 0.046 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IP_trans PF02121.18 ORY98874.1 - 1.3e-103 345.9 0.4 1.5e-103 345.7 0.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Mito_carr PF00153.27 ORY98876.1 - 3.2e-43 145.6 5.9 3.4e-16 58.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Lyase_1 PF00206.20 ORY98877.1 - 4.6e-44 151.1 0.0 7.3e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORY98877.1 - 4.1e-24 84.9 0.1 2.4e-23 82.5 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus MobA_MobL PF03389.15 ORY98877.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 MobA/MobL family ADP_ribosyl_GH PF03747.14 ORY98879.1 - 3.2e-21 76.3 0.2 6.1e-13 49.1 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylglycohydrolase HAMP PF00672.25 ORY98880.1 - 2.4e-156 508.1 77.7 2.8e-08 34.0 0.2 22.4 22 0 0 22 22 22 20 HAMP domain HATPase_c PF02518.26 ORY98880.1 - 1.1e-30 106.4 0.1 1.2e-29 103.1 0.1 3.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY98880.1 - 2.9e-27 95.1 2.4 2.5e-25 88.8 0.1 4.6 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 ORY98880.1 - 1.7e-16 60.0 0.5 1.7e-16 60.0 0.5 5.0 5 0 0 5 5 4 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.17 ORY98880.1 - 3.4e-13 49.4 0.9 31 4.6 0.0 15.3 17 0 0 17 17 17 0 Helix-turn-helix domain, rpiR family ImcF-related_N PF14331.6 ORY98880.1 - 2.9e-08 33.4 4.4 18 4.6 0.0 10.6 9 3 4 13 13 13 0 ImcF-related N-terminal domain DUF1843 PF08898.10 ORY98880.1 - 3.1e-06 27.6 22.0 21 5.7 0.0 14.8 19 0 0 19 19 19 0 Domain of unknown function (DUF1843) Laminin_II PF06009.12 ORY98880.1 - 3.2e-06 27.2 110.7 0.13 12.3 0.8 19.0 18 1 1 19 19 19 7 Laminin Domain II SpoIIID PF12116.8 ORY98880.1 - 3.8e-06 26.9 26.4 10 6.3 0.0 15.0 18 0 0 18 18 18 1 Stage III sporulation protein D Vac_Fusion PF02346.16 ORY98880.1 - 0.071 12.7 12.9 68 3.2 0.0 10.4 13 0 0 13 13 13 0 Chordopoxvirus multifunctional envelope protein A27 DUF1759 PF03564.15 ORY98880.1 - 0.13 12.2 31.1 15 5.5 0.0 13.1 17 0 0 17 17 17 0 Protein of unknown function (DUF1759) Pol_alpha_B_N PF08418.10 ORY98881.1 - 0.084 12.8 1.8 0.12 12.3 1.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TT_ORF2 PF02957.15 ORY98881.1 - 1.1 10.2 4.1 2.7 8.9 4.1 1.6 1 0 0 1 1 1 0 TT viral ORF2 TPR_2 PF07719.17 ORY98882.1 - 1.1e-13 50.1 10.1 0.0058 16.6 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY98882.1 - 5.3e-12 45.5 8.2 0.0032 18.2 0.0 6.9 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY98882.1 - 9.6e-12 45.2 7.6 0.00024 21.5 0.0 5.9 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY98882.1 - 6e-10 38.5 7.4 0.41 11.0 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY98882.1 - 1.6e-06 27.7 8.3 0.67 9.9 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY98882.1 - 3.9e-06 26.9 4.4 0.42 11.1 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY98882.1 - 6.9e-05 23.4 9.1 0.024 15.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY98882.1 - 0.00014 22.1 1.7 0.31 11.4 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY98882.1 - 0.0041 17.3 9.2 5.5 7.3 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 ORY98882.1 - 0.006 15.6 0.7 0.043 12.8 0.1 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 ORY98882.1 - 0.075 13.7 10.1 10 7.0 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY98882.1 - 0.076 13.1 11.0 5.6 7.2 0.0 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY98882.1 - 0.11 11.9 10.1 0.34 10.2 3.1 3.5 3 1 1 4 4 4 0 MalT-like TPR region TPR_9 PF13371.6 ORY98882.1 - 0.11 12.7 4.5 29 4.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY98882.1 - 0.97 10.3 4.0 11 7.0 0.3 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Sld5 PF05916.11 ORY98883.1 - 1.8e-24 86.3 1.0 2.6e-24 85.8 1.0 1.2 1 0 0 1 1 1 1 GINS complex protein HrpJ PF07201.11 ORY98883.1 - 0.0014 19.0 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 HrpJ-like domain Lyase_1 PF00206.20 ORY98885.1 - 1.1e-42 146.5 0.0 1.6e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Lyase Glyco_transf_5 PF08323.11 ORY98886.1 - 3.9e-18 66.0 0.1 2.4e-17 63.5 0.1 2.0 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 ORY98886.1 - 8.6e-18 64.4 0.0 2.2e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY98886.1 - 7.1e-14 52.4 0.0 1.5e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY98886.1 - 0.019 14.9 5.7 0.25 11.3 1.1 3.2 3 1 0 3 3 3 0 Glycosyltransferase Family 4 DUF3425 PF11905.8 ORY98887.1 - 2.8e-11 43.5 2.4 2.8e-11 43.5 2.4 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORY98887.1 - 3.2e-07 30.3 8.2 6.7e-07 29.3 8.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 ORY98887.1 - 0.02 14.6 0.6 0.02 14.6 0.6 1.7 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ZapB PF06005.12 ORY98887.1 - 6.1 7.4 10.9 0.14 12.6 0.7 2.6 2 0 0 2 2 2 0 Cell division protein ZapB KASH_CCD PF14662.6 ORY98887.1 - 7.9 6.3 12.4 0.17 11.7 3.5 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 ORY98887.1 - 9.3 6.4 21.6 0.16 12.1 14.3 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Cu-oxidase PF00394.22 ORY98888.1 - 4.2e-31 108.2 0.0 8e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY98888.1 - 2.9e-30 104.7 0.5 1e-19 70.7 0.1 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY98888.1 - 8.7e-20 70.8 13.9 1.5e-17 63.6 2.1 4.7 3 2 0 3 3 3 2 Multicopper oxidase FAD_binding_2 PF00890.24 ORY98889.1 - 5.6e-126 421.0 6.9 7.7e-126 420.5 6.9 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ORY98889.1 - 5.3e-45 152.5 0.8 8e-45 151.9 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ORY98889.1 - 7.8e-06 25.3 0.3 0.001 18.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY98889.1 - 2.6e-05 23.5 1.7 0.014 14.5 2.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ORY98889.1 - 9.2e-05 21.8 0.4 0.065 12.5 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 ORY98889.1 - 0.0026 17.0 0.3 0.0049 16.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY98889.1 - 0.0064 15.2 1.8 0.12 11.1 0.6 3.0 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 ORY98889.1 - 0.028 14.0 1.6 0.077 12.6 1.5 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY98889.1 - 0.045 12.8 2.7 0.062 12.3 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.7 ORY98889.1 - 0.7 9.2 5.0 2.9 7.2 1.6 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase UAA PF08449.11 ORY98892.1 - 1.3e-51 175.7 17.7 1.5e-51 175.5 17.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY98892.1 - 1.8e-09 37.9 23.0 4.3e-07 30.2 10.2 2.4 3 0 0 3 3 3 2 EamA-like transporter family DUF1003 PF06210.11 ORY98892.1 - 0.058 13.5 0.7 0.58 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Nuc_sug_transp PF04142.15 ORY98892.1 - 0.077 12.1 8.4 0.16 11.2 2.6 2.3 1 1 1 2 2 2 0 Nucleotide-sugar transporter DUF4078 PF13300.6 ORY98893.1 - 5.3e-21 74.7 9.3 5.3e-21 74.7 9.3 3.8 3 2 1 4 4 4 1 Domain of unknown function (DUF4078) Kisspeptin PF15152.6 ORY98893.1 - 1.7 9.4 5.0 3.5 8.5 0.4 2.6 2 0 0 2 2 2 0 Kisspeptin MBOAT_2 PF13813.6 ORY98894.1 - 6.3e-13 48.8 0.2 1.6e-12 47.5 0.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Cullin PF00888.22 ORY98895.1 - 2.6e-197 657.3 7.7 2.6e-197 657.3 7.7 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 ORY98895.1 - 3.8e-26 90.9 5.0 7.4e-26 90.0 4.2 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 ORY98895.1 - 0.0023 18.3 0.2 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 Phage tail assembly chaperone protein, TAC DUF3658 PF12395.8 ORY98895.1 - 0.013 15.4 0.7 0.086 12.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function Peptidase_S8 PF00082.22 ORY98896.1 - 4.2e-29 101.7 8.4 4.3e-28 98.4 8.4 2.2 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY98896.1 - 0.018 15.7 0.0 0.032 14.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 FH2 PF02181.23 ORY98897.1 - 7.6e-87 291.8 6.0 7.6e-87 291.8 6.0 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 ORY98897.1 - 8.7e-35 120.1 0.2 3.5e-34 118.1 0.2 2.1 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 ORY98897.1 - 7.8e-26 90.8 0.4 1.8e-25 89.6 0.4 1.7 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain KASH_CCD PF14662.6 ORY98897.1 - 0.0068 16.2 6.3 0.78 9.5 0.3 2.8 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 ORY98897.1 - 0.15 11.6 15.3 0.055 13.0 6.1 3.2 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Tup_N PF08581.10 ORY98897.1 - 5.2 7.4 8.5 0.83 10.0 2.4 2.9 2 0 0 2 2 2 0 Tup N-terminal Med10 PF09748.9 ORY98898.1 - 1.8e-17 63.4 0.1 2e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex GRDP-like PF07173.12 ORY98899.1 - 1.8e-16 61.0 0.9 8.7e-11 42.6 0.0 3.4 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like BTB PF00651.31 ORY98900.1 - 1.9e-35 121.5 3.3 3.3e-17 62.7 0.1 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 ORY98900.1 - 6.5e-08 33.0 0.0 3.4e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY98900.1 - 2.4e-07 30.9 0.0 7.6e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY98900.1 - 1.5e-06 28.7 0.0 5.9e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY98900.1 - 1.5e-05 25.0 0.0 0.0002 21.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 ORY98900.1 - 0.002 18.5 0.0 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat SNAP PF14938.6 ORY98900.1 - 0.061 12.8 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP BACK PF07707.15 ORY98900.1 - 0.061 13.4 1.9 0.093 12.8 0.1 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch Med12 PF09497.10 ORY98901.1 - 3.9e-24 84.7 0.2 1.3e-23 83.0 0.2 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 ORY98901.1 - 0.00026 20.0 4.6 0.0027 16.6 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic Mediator 12 subunit domain ATG16 PF08614.11 ORY98902.1 - 0.07 13.4 4.9 0.093 12.9 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RNase_HII PF01351.18 ORY98903.1 - 3.8e-42 144.4 0.0 7.4e-42 143.4 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease HII GOLD_2 PF13897.6 ORY98903.1 - 0.033 14.7 0.2 0.049 14.1 0.2 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PTPRCAP PF15713.5 ORY98903.1 - 0.13 12.6 5.5 0.21 11.9 5.5 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Coilin_N PF15862.5 ORY98903.1 - 0.44 10.4 7.6 0.8 9.5 7.6 1.4 1 0 0 1 1 1 0 Coilin N-terminus RNA_pol_Rbc25 PF08292.12 ORY98903.1 - 0.77 10.0 5.3 1.5 9.1 5.3 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF1115 PF06544.12 ORY98903.1 - 1.3 9.1 6.3 2.4 8.2 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) WASH-7_C PF14746.6 ORY98903.1 - 1.4 8.6 4.0 2.7 7.6 4.0 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Roughex PF06020.11 ORY98903.1 - 1.5 7.8 5.6 2.2 7.3 5.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Peptidase_S49_N PF08496.10 ORY98903.1 - 1.9 8.5 4.8 3.3 7.7 4.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF5321 PF17254.2 ORY98904.1 - 1.6e-09 37.4 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF2087 PF09860.9 ORY98904.1 - 0.093 12.9 0.2 0.23 11.7 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) SET PF00856.28 ORY98906.1 - 9.1e-17 62.0 0.0 1.5e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 ORY98906.1 - 9.5e-05 23.1 0.3 0.00024 21.8 0.1 1.7 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Sod_Fe_C PF02777.18 ORY98906.1 - 0.064 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Carb_kinase PF01256.17 ORY98907.1 - 2.1e-57 194.4 0.0 2.6e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 ORY98907.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 ORY98907.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Adeno_E4_ORF3 PF06931.11 ORY98907.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein Glyco_transf_8 PF01501.20 ORY98908.1 - 2.8e-22 79.5 0.5 4.1e-22 79.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ORY98908.1 - 0.00014 21.3 0.0 0.00052 19.5 0.0 1.7 1 1 0 2 2 2 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORY98908.1 - 0.03 14.3 0.6 0.05 13.6 0.6 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase tRNA_int_endo PF01974.17 ORY98909.1 - 8.2e-16 57.9 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Voltage_CLC PF00654.20 ORY98910.1 - 1.2e-89 301.0 25.6 1.2e-89 301.0 25.6 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY98910.1 - 7.7e-09 35.9 0.3 0.00082 19.8 0.1 2.6 2 0 0 2 2 2 2 CBS domain QCR10 PF09796.9 ORY98910.1 - 0.012 15.7 0.2 0.052 13.6 0.2 2.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) PDT PF00800.18 ORY98911.1 - 3.4e-64 216.0 0.1 4.7e-64 215.6 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 ORY98911.1 - 1.3e-20 73.5 0.6 2.9e-20 72.4 0.6 1.6 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 ORY98911.1 - 0.00012 21.8 0.0 0.00031 20.5 0.0 1.8 1 0 0 1 1 1 1 ACT domain Questin_oxidase PF14027.6 ORY98912.1 - 5.3e-85 285.9 0.1 6.5e-85 285.7 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like Lipase_3 PF01764.25 ORY98913.1 - 2.2e-33 115.1 0.0 3.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 ORY98913.1 - 9.2e-06 25.5 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ORY98913.1 - 0.004 16.4 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 ORY98913.1 - 0.0092 15.6 0.1 0.051 13.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORY98913.1 - 0.033 14.8 0.0 0.05 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ORY98913.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase RRF PF01765.19 ORY98914.1 - 9.1e-48 162.3 11.0 1.2e-47 161.9 11.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor PEP-utilisers_N PF05524.13 ORY98914.1 - 0.089 13.0 2.4 2.2 8.5 0.1 3.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal YtzH PF14165.6 ORY98914.1 - 0.1 13.0 1.9 0.16 12.3 0.9 2.0 2 1 0 2 2 2 0 YtzH-like protein EspB PF05802.11 ORY98914.1 - 0.11 12.5 6.1 0.052 13.5 1.8 2.0 2 0 0 2 2 2 0 Enterobacterial EspB protein Baculo_PEP_C PF04513.12 ORY98914.1 - 0.94 9.5 7.0 1.3 9.0 1.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 ORY98914.1 - 2.1 9.0 9.0 1.7 9.2 6.6 2.1 2 1 0 2 2 2 0 YtxH-like protein DUF4404 PF14357.6 ORY98914.1 - 5.9 7.6 7.5 9.3 7.0 1.6 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) DUF883 PF05957.13 ORY98914.1 - 7.8 7.2 6.7 11 6.7 2.4 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PAP2 PF01569.21 ORY98915.1 - 2.5e-06 27.3 16.8 0.00018 21.3 12.4 3.4 2 1 0 2 2 2 1 PAP2 superfamily UbiA PF01040.18 ORY98915.1 - 0.001 18.4 1.3 0.001 18.4 1.3 1.8 2 0 0 2 2 2 1 UbiA prenyltransferase family Epiglycanin_C PF14654.6 ORY98915.1 - 0.012 15.7 0.5 0.2 11.7 0.1 2.2 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF212 PF02681.14 ORY98915.1 - 0.013 15.6 0.6 1.2 9.2 0.0 2.5 1 1 1 2 2 2 0 Divergent PAP2 family DUF3021 PF11457.8 ORY98915.1 - 0.04 14.2 0.9 0.04 14.2 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF2207 PF09972.9 ORY98915.1 - 0.05 12.4 3.1 0.082 11.7 3.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Lipase_3 PF01764.25 ORY98916.1 - 3.5e-35 120.9 0.0 5.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORY98916.1 - 4.1e-05 23.0 0.1 0.0001 21.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 ORY98916.1 - 8.7e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 ORY98916.1 - 0.0011 18.5 0.4 0.0061 16.1 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORY98916.1 - 0.041 14.5 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 ORY98916.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF4389 PF14333.6 ORY98919.1 - 0.057 13.3 1.0 0.61 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Methyltransf_25 PF13649.6 ORY98921.1 - 8.7e-09 36.0 0.0 2.2e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY98921.1 - 4.6e-08 33.6 0.0 1.5e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 ORY98921.1 - 5.1e-05 22.0 0.0 6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 ORY98921.1 - 0.0047 17.6 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY98921.1 - 0.0053 16.1 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY98921.1 - 0.0085 15.9 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY98921.1 - 0.035 13.9 0.0 0.072 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PHO4 PF01384.20 ORY98922.1 - 4.7e-124 413.8 18.5 5.5e-124 413.6 18.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family polyprenyl_synt PF00348.17 ORY98923.1 - 5.1e-66 222.4 0.0 6e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Arrestin_C PF02752.22 ORY98924.1 - 1.9e-07 31.6 0.1 4.3e-06 27.2 0.1 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY98924.1 - 0.00016 21.7 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY98924.1 - 0.0017 18.1 0.1 0.0058 16.3 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like UPF0160 PF03690.13 ORY98926.1 - 2e-132 441.7 0.0 2.3e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) HLH PF00010.26 ORY98927.1 - 3e-14 52.7 1.2 6.6e-14 51.6 1.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RNA_pol_Rpc4 PF05132.14 ORY98927.1 - 2.1 8.7 6.8 1.6 9.1 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 UPF0242 PF06785.11 ORY98927.1 - 3.3 7.8 16.9 2.9e+02 1.4 16.9 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pneumo_att_G PF05539.11 ORY98927.1 - 6 6.4 13.2 7.7 6.0 13.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G YabA PF06156.13 ORY98927.1 - 6.4 7.5 11.6 0.35 11.5 2.4 2.8 1 1 0 2 2 2 0 Initiation control protein YabA p450 PF00067.22 ORY98928.1 - 3.3e-37 128.3 0.0 3.3e-28 98.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 UvrD-helicase PF00580.21 ORY98929.1 - 2.4e-62 211.3 2.6 9.2e-62 209.4 2.6 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ORY98929.1 - 8.5e-60 203.0 0.2 6.6e-58 196.7 0.0 3.1 2 2 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ORY98929.1 - 3.8e-29 101.9 0.0 9e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ORY98929.1 - 3.3e-10 39.6 0.0 1e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ORY98929.1 - 4.9e-06 26.4 0.2 4.3e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 ORY98929.1 - 0.012 15.4 0.1 11 5.6 0.0 3.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DDHD PF02862.17 ORY98930.1 - 3.1e-46 158.3 0.4 2.1e-45 155.6 0.0 2.2 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 ORY98930.1 - 3.7e-05 24.2 0.2 0.051 14.2 0.0 3.2 1 1 1 2 2 2 2 WWE domain Abhydrolase_1 PF00561.20 ORY98930.1 - 0.051 13.2 0.0 0.2 11.3 0.0 2.0 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY98930.1 - 0.056 12.7 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY98930.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 ORY98930.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Complex1_LYR_2 PF13233.6 ORY98931.1 - 3.2e-12 47.0 3.8 4.2e-12 46.6 3.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ORY98931.1 - 0.0033 17.4 3.5 0.0041 17.1 1.5 2.2 2 1 1 3 3 3 1 Complex 1 protein (LYR family) Bin3 PF06859.12 ORY98931.1 - 0.088 13.5 0.2 0.43 11.2 0.1 1.8 1 1 1 2 2 2 0 Bicoid-interacting protein 3 (Bin3) LRR_4 PF12799.7 ORY98933.1 - 0.0038 17.6 2.6 4.3 7.9 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) NTP_transf_2 PF01909.23 ORY98934.1 - 3.5e-11 43.2 0.0 8.3e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 ORY98934.1 - 2e-05 24.7 0.0 4.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 ORY98934.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RIO1 PF01163.22 ORY98935.1 - 2.3e-72 242.6 0.8 2.3e-72 242.6 0.8 2.3 3 0 0 3 3 3 1 RIO1 family PRTP PF01366.18 ORY98935.1 - 0.19 9.7 6.9 0.35 8.9 6.9 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Rhodanese PF00581.20 ORY98936.1 - 7.1e-09 36.2 0.0 1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S41 PF03572.18 ORY98936.1 - 0.055 13.0 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S41 Glyco_trans_2_3 PF13632.6 ORY98937.1 - 9e-15 55.1 0.5 9e-15 55.1 0.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 PcfK PF14058.6 ORY98937.1 - 0.074 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 PcfK-like protein DUF4131 PF13567.6 ORY98937.1 - 4.1 7.0 4.7 8.6 6.0 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Dynamin_N PF00350.23 ORY98938.1 - 7.5e-19 68.4 0.9 4.5e-18 65.9 0.0 2.7 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ORY98938.1 - 1.9e-10 40.8 0.1 3.6e-09 36.7 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY98938.1 - 1.2e-07 31.5 0.7 3.2e-06 26.8 0.6 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY98938.1 - 0.00028 20.8 1.1 1.1 9.1 0.0 3.1 1 1 1 2 2 2 2 RsgA GTPase IIGP PF05049.13 ORY98938.1 - 0.0019 17.4 0.2 0.011 14.8 0.0 2.2 2 1 1 3 3 3 1 Interferon-inducible GTPase (IIGP) cobW PF02492.19 ORY98938.1 - 0.0072 15.9 0.2 0.78 9.3 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 ORY98938.1 - 0.022 14.7 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 ORY98938.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY98938.1 - 0.022 15.1 0.4 0.19 12.1 0.3 2.7 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 ORY98938.1 - 0.068 12.4 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 Septin Roc PF08477.13 ORY98938.1 - 0.081 13.1 0.1 1.3 9.2 0.0 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 ORY98938.1 - 0.1 12.1 0.2 12 5.4 0.0 2.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Cas9_Topo PF17894.1 ORY98938.1 - 0.1 12.7 0.2 0.64 10.1 0.0 2.4 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 PglZ PF08665.12 ORY98938.1 - 7.7 6.6 8.3 1.6 8.8 0.1 3.5 4 0 0 4 4 4 0 PglZ domain She9_MDM33 PF05546.11 ORY98939.1 - 1.6e-68 230.4 12.7 2.4e-68 229.9 12.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family GAGBD PF16828.5 ORY98939.1 - 0.079 13.1 6.5 0.13 12.3 6.5 1.3 1 0 0 1 1 1 0 GAG-binding domain on surface antigen FtsL PF04999.13 ORY98939.1 - 0.15 12.1 3.2 0.47 10.5 0.0 2.9 2 1 0 2 2 2 0 Cell division protein FtsL DUF1657 PF07870.11 ORY98939.1 - 0.65 9.9 8.2 11 6.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) DUF4337 PF14235.6 ORY98939.1 - 0.82 9.8 5.5 6.2 6.9 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Nic96 PF04097.14 ORY98942.1 - 1.7e-145 486.0 0.5 2.5e-145 485.4 0.5 1.2 1 0 0 1 1 1 1 Nup93/Nic96 F-box-like PF12937.7 ORY98944.1 - 3.3e-05 23.7 4.7 0.00012 21.9 4.7 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 ORY98944.1 - 0.0011 18.6 11.3 0.24 11.2 0.0 6.1 6 1 1 7 7 7 2 Leucine rich repeat F-box_5 PF18511.1 ORY98944.1 - 0.068 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 ORY98944.1 - 0.16 12.5 14.7 9.1 6.9 0.0 6.6 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY98944.1 - 3.2 7.7 8.7 47 4.0 8.7 2.9 1 1 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 ORY98946.1 - 5.7e-35 120.6 0.0 5.7e-35 120.6 0.0 2.0 3 0 0 3 3 2 1 Fungal specific transcription factor domain API5 PF05918.11 ORY98946.1 - 0.0046 15.8 3.1 0.0081 15.0 3.1 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) TFIIA PF03153.13 ORY98946.1 - 0.0052 16.8 25.0 0.0052 16.8 25.0 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 ORY98946.1 - 0.032 14.2 18.3 0.028 14.3 12.2 2.2 2 0 0 2 2 2 0 Velvet factor EPL1 PF10513.9 ORY98946.1 - 0.053 13.9 11.2 0.17 12.3 4.9 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Pex14_N PF04695.13 ORY98946.1 - 0.33 11.6 32.1 1 10.0 20.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 ORY98946.1 - 0.35 10.8 20.2 0.1 12.5 14.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PIEZO PF15917.5 ORY98946.1 - 0.39 10.1 14.4 0.8 9.1 14.4 1.4 1 0 0 1 1 1 0 Piezo PAT1 PF09770.9 ORY98946.1 - 0.73 8.0 19.5 1.2 7.3 19.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RP-C_C PF11800.8 ORY98946.1 - 0.81 9.7 13.6 0.57 10.2 7.4 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Serinc PF03348.15 ORY98946.1 - 0.94 8.3 6.9 1.6 7.5 6.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Exonuc_VII_L PF02601.15 ORY98946.1 - 1.6 8.2 10.5 2.6 7.5 10.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCDC53 PF10152.9 ORY98946.1 - 2.1 8.8 19.4 0.86 10.0 9.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Neur_chan_memb PF02932.16 ORY98946.1 - 2.2 8.3 12.0 0.48 10.4 6.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 ORY98946.1 - 2.4 8.2 6.8 4.7 7.3 6.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 ORY98946.1 - 3.2 7.5 9.4 8.3 6.1 9.4 1.7 1 0 0 1 1 1 0 Connexin Zip PF02535.22 ORY98946.1 - 3.6 6.7 6.5 1.6 7.9 1.8 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter ASD2 PF08687.11 ORY98946.1 - 5 6.6 19.3 0.35 10.4 11.5 2.0 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 CobT PF06213.12 ORY98946.1 - 5.1 6.4 16.7 0.35 10.2 10.9 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SPX PF03105.19 ORY98946.1 - 5.6 6.8 22.1 3.9 7.3 7.4 2.2 2 0 0 2 2 2 0 SPX domain Presenilin PF01080.17 ORY98946.1 - 7 5.3 22.8 1.3 7.7 15.5 2.3 2 0 0 2 2 2 0 Presenilin Ctr PF04145.15 ORY98946.1 - 8.8 6.9 11.0 42 4.7 6.1 2.7 2 0 0 2 2 2 0 Ctr copper transporter family Hydin_ADK PF17213.3 ORY98946.1 - 8.9 6.5 18.0 0.35 11.1 9.4 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Spt4 PF06093.13 ORY98947.1 - 4.6e-31 106.7 2.5 5.6e-31 106.5 2.5 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Peptidase_M24 PF00557.24 ORY98949.1 - 9.5e-49 165.9 0.7 2.1e-48 164.8 0.4 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ORY98949.1 - 5.7e-06 27.0 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF1713 PF08213.11 ORY98950.1 - 9e-14 51.1 20.7 1.2e-13 50.7 20.7 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Nup54 PF13874.6 ORY98951.1 - 3.3e-40 137.4 4.2 3.3e-40 137.4 4.2 2.4 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Sec20 PF03908.13 ORY98951.1 - 1.2 9.1 4.8 1 9.3 0.4 2.7 2 1 1 3 3 3 0 Sec20 NifQ PF04891.12 ORY98951.1 - 2.7 8.3 10.0 0.34 11.3 0.3 2.9 2 1 1 3 3 3 0 NifQ Coiled-coil_56 PF09813.9 ORY98952.1 - 1e-05 25.5 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF2927 PF11150.8 ORY98953.1 - 0.65 10.0 5.7 3.1 7.8 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2927) MFS_1 PF07690.16 ORY98954.1 - 3.1e-41 141.5 33.6 4.4e-41 141.0 32.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY98954.1 - 6.1e-21 74.8 14.8 4.7e-18 65.3 0.9 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter BT1 PF03092.16 ORY98954.1 - 0.62 8.2 18.4 0.21 9.8 3.8 3.1 2 1 0 3 3 3 0 BT1 family Fasciclin PF02469.22 ORY98955.1 - 4.7e-90 298.4 0.8 1.5e-21 76.9 0.1 5.2 5 0 0 5 5 5 5 Fasciclin domain Tetraspanin PF00335.20 ORY98956.1 - 0.00022 21.0 4.2 0.0059 16.3 3.8 2.1 1 1 1 2 2 2 2 Tetraspanin family RCR PF12273.8 ORY98956.1 - 0.0033 18.1 3.1 0.0033 18.1 3.1 2.3 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red WBP-1 PF11669.8 ORY98956.1 - 0.12 13.1 0.4 0.12 13.1 0.4 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF3382 PF11862.8 ORY98956.1 - 0.51 10.7 4.3 6.8 7.0 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Ribosomal_60s PF00428.19 ORY98956.1 - 5.4 7.7 7.2 14 6.3 7.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Kin17_mid PF10357.9 ORY98958.1 - 2.2e-49 166.5 1.0 3.8e-49 165.8 1.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 ORY98958.1 - 0.007 16.7 5.4 0.013 15.8 5.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type NRho PF16733.5 ORY98958.1 - 0.019 15.0 0.1 2 8.5 0.0 2.8 2 1 1 3 3 3 0 Rhomboid N-terminal domain zf-C2H2_jaz PF12171.8 ORY98958.1 - 0.027 14.8 7.1 0.049 13.9 7.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Glyoxalase_3 PF13468.6 ORY98958.1 - 0.037 14.2 0.9 0.089 12.9 0.8 1.7 1 1 1 2 2 2 0 Glyoxalase-like domain ADH_N PF08240.12 ORY98960.1 - 7.2e-27 93.4 3.1 9.6e-27 93.0 2.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY98960.1 - 1.4e-16 60.7 0.0 2.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY98960.1 - 0.00083 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY98960.1 - 0.097 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GATA PF00320.27 ORY98961.1 - 0.002 17.7 4.7 0.0036 16.9 4.7 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-CHCC PF10276.9 ORY98961.1 - 0.017 15.2 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger domain SQS_PSY PF00494.19 ORY98962.1 - 1.1e-46 159.5 0.0 1.3e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Asp PF00026.23 ORY98965.1 - 4.8e-56 190.5 1.0 5.9e-56 190.2 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY98965.1 - 3e-10 40.6 4.9 1.5e-06 28.6 0.5 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY98965.1 - 0.00016 21.5 0.0 0.0033 17.2 0.0 2.6 3 1 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY98965.1 - 0.0007 20.2 0.2 1.7 9.4 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY98965.1 - 0.12 12.9 0.0 32 5.2 0.0 3.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease TatD_DNase PF01026.21 ORY98966.1 - 1.6e-45 155.5 0.0 1.9e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase zf-UBP_var PF17807.1 ORY98966.1 - 0.15 11.9 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Variant UBP zinc finger Phosphoesterase PF04185.14 ORY98967.1 - 9e-71 238.9 0.3 1.2e-70 238.5 0.3 1.2 1 0 0 1 1 1 1 Phosphoesterase family DUF1325 PF07039.11 ORY98969.1 - 9.5e-35 119.6 0.1 1.5e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 ORY98969.1 - 0.00051 19.8 0.1 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 ORY98969.1 - 0.011 16.2 0.0 6.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Agenet domain TUDOR_5 PF18359.1 ORY98969.1 - 0.035 13.8 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 ORY98969.1 - 0.077 13.0 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) WD40 PF00400.32 ORY98970.1 - 7e-39 131.1 17.9 1.1e-06 29.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY98970.1 - 1.1e-10 41.7 0.1 0.11 12.8 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain VIT_2 PF13757.6 ORY98970.1 - 0.11 12.4 0.0 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Atg14 PF10186.9 ORY98970.1 - 0.77 8.8 2.5 1.1 8.3 2.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tubulin-binding PF00418.19 ORY98971.1 - 4.5e-96 314.5 58.9 8e-13 48.2 1.0 9.2 9 0 0 9 9 9 8 Tau and MAP protein, tubulin-binding repeat AcrZ PF10766.9 ORY98971.1 - 0.4 10.3 2.2 7.6 6.2 0.0 3.2 4 0 0 4 4 4 0 Multidrug efflux pump-associated protein AcrZ Tmemb_cc2 PF10267.9 ORY98971.1 - 0.89 8.6 35.0 2.7 7.1 9.8 5.5 1 1 2 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein Kinesin PF00225.23 ORY98972.1 - 4.3e-40 137.7 0.0 5e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY98972.1 - 3.5e-23 82.2 0.0 4.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding NDUF_B8 PF05821.11 ORY98973.1 - 7.3e-10 39.0 0.5 1.3e-09 38.2 0.5 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) RRM_1 PF00076.22 ORY98974.1 - 8.5e-26 89.6 0.0 4.7e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 ORY98974.1 - 3.8e-24 82.9 0.2 4.5e-06 26.1 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 ORY98974.1 - 0.00018 21.3 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif Pkinase PF00069.25 ORY98975.1 - 8.8e-59 199.0 0.0 3.1e-50 171.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY98975.1 - 1.5e-31 109.7 0.0 6.8e-29 100.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY98975.1 - 8.2e-12 45.0 0.0 1.6e-11 44.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY98975.1 - 0.0063 15.3 2.5 0.031 13.1 2.7 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY98975.1 - 0.0069 16.3 4.3 0.026 14.5 4.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY98975.1 - 0.023 14.3 0.7 0.037 13.6 0.4 1.4 1 1 0 1 1 1 0 RIO1 family DUF3526 PF12040.8 ORY98975.1 - 0.11 12.9 1.1 0.15 12.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) Ribosomal_L7Ae PF01248.26 ORY98976.1 - 1.1e-26 92.4 1.3 1.4e-26 92.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HD_2 PF12917.7 ORY98976.1 - 0.091 12.5 0.8 0.11 12.2 0.8 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme FliM PF02154.15 ORY98976.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 Flagellar motor switch protein FliM Ribosomal_L23eN PF03939.13 ORY98977.1 - 9.9e-24 83.3 13.2 2e-23 82.4 13.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORY98977.1 - 5.1e-15 55.6 1.3 5.1e-15 55.6 1.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 ORY98977.1 - 0.012 15.9 0.4 0.014 15.7 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5451) ANAPC4_WD40 PF12894.7 ORY98978.1 - 3e-14 53.1 6.0 0.0017 18.6 0.0 6.8 4 1 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY98978.1 - 2.3e-06 28.2 18.3 1.1 10.3 3.2 9.2 11 0 0 11 11 11 2 WD domain, G-beta repeat KH_6 PF15985.5 ORY98979.1 - 1.7e-18 66.7 0.1 2.9e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 ORY98979.1 - 1.9e-12 46.9 0.1 3.3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain ECR1_N PF14382.6 ORY98979.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region SNF5 PF04855.12 ORY98980.1 - 1.1e-64 218.4 10.8 4.9e-37 128.0 0.0 3.2 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 Inj_translocase PF16928.5 ORY98980.1 - 0.0063 16.0 12.9 0.011 15.2 12.9 1.3 1 0 0 1 1 1 1 DNA/protein translocase of phage P22 injectosome IPP-2 PF04979.14 ORY98980.1 - 0.031 15.0 7.0 0.075 13.8 7.0 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) TFIIA PF03153.13 ORY98980.1 - 0.085 12.8 18.8 0.014 15.4 13.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 ORY98980.1 - 0.58 9.8 2.6 1.2 8.7 2.6 1.5 1 0 0 1 1 1 0 PepSY-associated TM region O-antigen_lig PF13425.6 ORY98980.1 - 0.58 8.9 1.7 0.84 8.4 1.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Androgen_recep PF02166.16 ORY98980.1 - 0.87 8.4 15.8 4.8 5.9 17.0 1.6 2 0 0 2 2 2 0 Androgen receptor Spt20 PF12090.8 ORY98980.1 - 0.93 9.1 21.9 1.9 8.1 21.9 1.5 1 0 0 1 1 1 0 Spt20 family PNISR PF15996.5 ORY98980.1 - 0.97 9.7 15.2 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF702 PF05142.12 ORY98980.1 - 3.6 8.1 8.9 11 6.4 8.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4834 PF16118.5 ORY98980.1 - 4.7 8.3 9.0 16 6.6 9.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 ORY98980.1 - 5.4 7.6 14.5 0.67 10.6 7.4 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region THOC2_N PF16134.5 ORY98981.1 - 2.3e-108 363.5 2.4 2.3e-108 363.5 2.4 2.4 2 1 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 ORY98981.1 - 7.3e-77 258.5 1.9 7.3e-77 258.5 1.9 2.7 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 ORY98981.1 - 1.2e-22 79.7 0.0 1.4e-21 76.3 0.0 2.7 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Peptidase_C92 PF05708.12 ORY98981.1 - 0.084 13.0 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family HetR_C PF18460.1 ORY98982.1 - 0.028 14.3 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain ETC_C1_NDUFA4 PF04800.12 ORY98983.1 - 3.8e-34 116.8 3.1 3.8e-34 116.8 3.1 1.4 2 0 0 2 2 2 1 ETC complex I subunit conserved region Lon_C PF05362.13 ORY98984.1 - 8e-73 244.4 0.5 1.6e-72 243.4 0.5 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORY98984.1 - 9.2e-25 87.7 2.1 1.1e-24 87.5 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORY98984.1 - 1.4e-21 77.3 0.0 3.3e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY98984.1 - 4.2e-07 30.0 0.0 9.7e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORY98984.1 - 4.8e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 ORY98984.1 - 2.1e-05 24.8 0.0 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 ORY98984.1 - 0.00019 20.5 0.0 0.00043 19.3 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 ORY98984.1 - 0.00038 20.2 0.1 0.0027 17.5 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY98984.1 - 0.0014 18.7 0.0 0.0066 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORY98984.1 - 0.0029 18.0 0.9 0.013 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 ORY98984.1 - 0.0034 17.1 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORY98984.1 - 0.0081 16.7 0.0 0.026 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ORY98984.1 - 0.017 15.0 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY98984.1 - 0.021 15.2 0.0 0.067 13.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 ORY98984.1 - 0.041 13.1 1.0 0.089 12.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 ORY98984.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 ORY98984.1 - 0.087 13.0 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY98984.1 - 0.33 11.4 0.1 0.33 11.4 0.1 2.6 1 1 1 2 2 1 0 AAA domain Alpha-amylase_C PF02806.18 ORY98985.1 - 7.3e-24 84.1 0.0 2e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 ORY98985.1 - 7.1e-17 61.5 0.1 2.1e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ORY98985.1 - 2.6e-15 56.8 0.4 9.3e-11 41.9 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Aminotran_1_2 PF00155.21 ORY98985.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DSPc PF00782.20 ORY98986.1 - 4.7e-25 87.9 0.0 7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 ORY98986.1 - 6.5e-09 36.3 0.0 5.8e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase2 PF03162.13 ORY98986.1 - 0.0062 16.1 0.1 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 ORY98986.1 - 0.028 14.7 0.0 0.068 13.5 0.0 1.6 2 0 0 2 2 2 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 ORY98986.1 - 0.031 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Adaptin_N PF01602.20 ORY98987.1 - 2.6e-141 471.8 9.5 3.2e-141 471.5 9.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY98987.1 - 1.5e-65 220.1 5.2 3.5e-64 215.7 0.7 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY98987.1 - 6.8e-18 64.9 6.7 7.7e-08 32.6 0.2 5.1 2 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 ORY98987.1 - 1.5e-11 43.5 1.4 0.01 16.1 0.1 5.3 6 0 0 6 6 5 2 HEAT repeat Arm PF00514.23 ORY98987.1 - 4.1e-07 29.8 7.1 0.011 15.7 0.0 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 ORY98987.1 - 0.00015 21.1 0.3 0.089 12.0 0.1 2.7 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 ORY98987.1 - 0.0011 19.5 7.6 3 8.5 0.1 6.1 6 1 1 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 ORY98987.1 - 0.0017 17.9 2.2 3 7.3 0.1 3.8 3 1 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 ORY98987.1 - 0.0028 17.8 4.3 8.1 6.7 0.4 4.2 2 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 ORY98987.1 - 0.0037 17.7 0.5 0.13 12.7 0.0 3.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 ORY98987.1 - 0.076 13.1 4.7 0.25 11.5 0.1 3.4 3 1 0 4 4 4 0 Parkin co-regulated protein M20_dimer PF07687.14 ORY98987.1 - 0.19 11.7 0.0 0.59 10.1 0.0 1.8 1 0 0 1 1 1 0 Peptidase dimerisation domain Vac14_Fab1_bd PF12755.7 ORY98987.1 - 0.29 11.7 2.7 0.66 10.6 0.2 2.8 3 0 0 3 3 2 0 Vacuolar 14 Fab1-binding region Abhydrolase_3 PF07859.13 ORY98988.1 - 1.1e-21 77.7 0.0 1.9e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY98988.1 - 3.8e-08 32.6 0.0 6.5e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Copper-fist PF00649.18 ORY98989.1 - 8.6e-21 73.1 3.0 8.6e-21 73.1 3.0 1.9 2 0 0 2 2 2 1 Copper fist DNA binding domain DUF3716 PF12511.8 ORY98989.1 - 0.14 12.2 7.2 2.8 8.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) CDP-OH_P_transf PF01066.21 ORY98990.1 - 3.9e-15 56.4 0.5 3.9e-15 56.4 0.5 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase COX5A PF02284.16 ORY98992.1 - 5.7e-42 141.9 0.1 7.5e-42 141.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ATP-synt_G PF04718.15 ORY98993.1 - 2.8e-23 82.6 0.3 3.3e-23 82.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF3212 PF11486.8 ORY98993.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3212) Yqai PF09466.10 ORY98993.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein Yqai Endonuclease_NS PF01223.23 ORY98994.1 - 4.3e-69 232.8 0.1 5e-69 232.6 0.1 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease 3H PF02829.14 ORY98995.1 - 0.0034 17.6 3.8 0.98 9.8 0.3 4.3 3 0 0 3 3 3 2 3H domain RPW8 PF05659.11 ORY98995.1 - 0.053 13.2 30.3 0.46 10.2 2.3 5.7 2 1 2 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Shugoshin_N PF07558.11 ORY98995.1 - 0.12 12.3 0.2 0.12 12.3 0.2 3.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region mCpol PF18182.1 ORY98996.1 - 0.026 14.8 0.2 0.057 13.8 0.2 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain NYD-SP28_assoc PF14775.6 ORY98996.1 - 0.17 12.0 2.3 0.35 11.0 2.3 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cep57_CLD_2 PF14197.6 ORY98996.1 - 0.89 9.7 8.9 0.17 12.0 3.4 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 GPI-anchored PF10342.9 ORY98997.1 - 0.0087 16.8 1.5 0.016 16.0 1.5 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cohesin PF00963.18 ORY98997.1 - 0.064 13.5 0.5 0.08 13.2 0.5 1.2 1 0 0 1 1 1 0 Cohesin domain DUF1573 PF07610.11 ORY98997.1 - 0.1 12.6 0.1 0.35 10.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1573) LSR PF05624.14 ORY98997.1 - 0.21 11.6 0.1 0.54 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) EF-hand_7 PF13499.6 ORY98998.1 - 1.8e-15 57.1 0.0 3e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORY98998.1 - 1.9e-13 50.0 0.6 3.5e-09 36.4 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY98998.1 - 1.4e-11 43.3 1.7 0.0037 17.1 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 ORY98998.1 - 5.2e-10 38.2 4.1 1e-06 27.8 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 ORY98998.1 - 1.6e-06 27.3 5.5 0.00018 20.8 0.0 3.9 4 0 0 4 4 4 1 EF hand TilS PF09179.11 ORY98998.1 - 0.052 14.1 0.9 1.2 9.7 0.2 2.4 2 0 0 2 2 2 0 TilS substrate binding domain LAT PF15234.6 ORY98998.1 - 0.1 12.3 3.1 0.12 12.0 3.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Sigma70_ner PF04546.13 ORY98998.1 - 0.11 12.4 5.0 0.18 11.6 5.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 ORY98998.1 - 0.4 11.1 10.9 0.82 10.1 10.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ORY98998.1 - 0.41 9.9 9.6 0.59 9.4 9.6 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ORY98998.1 - 0.93 7.5 7.6 1 7.4 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi EF-hand_4 PF12763.7 ORY98998.1 - 1.4 8.9 5.4 0.37 10.8 0.7 2.4 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF2457 PF10446.9 ORY98998.1 - 4.4 6.3 11.2 5.8 5.9 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 ORY98998.1 - 4.5 7.7 12.8 8.3 6.9 12.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytomega_UL84 PF06284.11 ORY98998.1 - 6.6 5.1 5.2 9.1 4.6 5.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF543 PF04418.12 ORY98999.1 - 1.8e-24 85.5 0.0 2e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) 2TM PF13239.6 ORY98999.1 - 0.046 14.0 0.1 0.059 13.7 0.1 1.3 1 1 0 1 1 1 0 2TM domain PGF-CTERM PF18204.1 ORY98999.1 - 2.5 8.2 4.5 6.2 6.9 0.2 2.3 2 0 0 2 2 2 0 PGF-CTERM motif E1_dh PF00676.20 ORY99000.1 - 2.3e-117 391.2 0.1 2.8e-117 390.9 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORY99000.1 - 0.03 13.6 0.0 0.08 12.1 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase COMM_domain PF07258.14 ORY99000.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 COMM domain 4_1_CTD PF05902.13 ORY99001.1 - 2.3 8.3 8.1 4.8 7.3 8.1 1.5 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) 2-Hacid_dh_C PF02826.19 ORY99003.1 - 4.7e-47 159.6 0.0 8.2e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY99003.1 - 1.9e-35 121.5 0.0 2.5e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY99003.1 - 0.0035 17.5 1.1 0.0067 16.6 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPGT PF00201.18 ORY99003.1 - 0.015 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase ACT PF01842.25 ORY99003.1 - 0.044 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain IlvN PF07991.12 ORY99003.1 - 0.059 12.9 0.3 0.43 10.1 0.0 2.4 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_10 PF13460.6 ORY99004.1 - 5.4e-32 111.2 0.0 6.9e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY99004.1 - 2.6e-09 37.0 0.0 4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY99004.1 - 1.6e-08 34.3 0.0 2.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY99004.1 - 0.002 18.6 0.1 0.0044 17.4 0.1 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ORY99004.1 - 0.0053 15.9 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain BRCA-2_OB3 PF09104.10 ORY99004.1 - 0.0075 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 adh_short PF00106.25 ORY99004.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 ORY99004.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain F-box-like PF12937.7 ORY99005.1 - 0.0023 17.8 0.5 0.0064 16.4 0.5 1.9 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.6 ORY99005.1 - 0.13 13.1 0.8 15 6.7 0.0 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat AT_hook PF02178.19 ORY99005.1 - 1.9 8.6 12.3 0.66 10.1 2.8 3.0 2 0 0 2 2 2 0 AT hook motif DEAD PF00270.29 ORY99006.1 - 7.4e-34 117.0 0.6 2.1e-33 115.6 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY99006.1 - 8.6e-28 96.9 0.0 2.7e-27 95.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 ORY99006.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY99006.1 - 0.95 9.7 3.7 1.3 9.3 1.1 2.6 3 1 0 3 3 3 0 AAA domain ubiquitin PF00240.23 ORY99007.1 - 6.4e-69 227.7 7.2 5.2e-34 115.8 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 ORY99007.1 - 3.8e-32 109.9 6.7 1.4e-15 56.8 0.7 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY99007.1 - 1.7e-12 47.6 2.4 0.0001 22.7 0.2 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY99007.1 - 3.3e-08 33.8 1.3 0.0074 16.6 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY99007.1 - 1.5e-07 31.5 0.4 0.029 14.5 0.1 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 ORY99007.1 - 2.6e-07 30.5 0.6 0.023 14.6 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 ORY99007.1 - 1.4e-06 28.8 0.1 0.073 13.6 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY99007.1 - 2.9e-05 24.0 0.1 0.21 11.4 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 ORY99007.1 - 0.00011 22.2 8.6 9 6.4 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-like domain DUF3861 PF12977.7 ORY99007.1 - 0.00038 20.5 0.3 0.9 9.7 0.0 2.2 1 1 1 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 ORY99007.1 - 0.0087 15.9 0.8 4.3 7.3 0.1 2.4 2 0 0 2 2 2 2 ACT domain DUF2870 PF11069.8 ORY99007.1 - 0.016 15.6 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Raf1_HTH PF18579.1 ORY99007.1 - 0.052 13.3 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Big_7 PF17957.1 ORY99007.1 - 0.053 14.3 0.0 18 6.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig domain Big_3_3 PF13750.6 ORY99007.1 - 0.06 13.0 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.6 ORY99007.1 - 0.097 13.3 0.1 25 5.6 0.0 2.3 2 0 0 2 2 2 0 ACT domain UDP-g_GGTase PF06427.11 ORY99007.1 - 0.13 12.4 1.5 1.1 9.4 0.1 2.4 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase Tash_PEST PF07708.11 ORY99007.1 - 0.17 12.1 9.6 2.7 8.2 1.5 2.3 2 0 0 2 2 2 0 Tash protein PEST motif FERM_f0 PF16511.5 ORY99007.1 - 0.22 11.9 2.0 35 4.8 0.1 3.3 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Plexin_cytopl PF08337.12 ORY99007.1 - 0.56 8.8 5.5 5.3 5.6 0.5 2.8 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain HAD_2 PF13419.6 ORY99008.1 - 1e-16 61.5 0.0 2e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY99008.1 - 1.7e-14 54.6 0.0 2.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY99008.1 - 1.6e-08 34.5 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ORY99008.1 - 0.17 12.0 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Kinesin PF00225.23 ORY99009.1 - 4.3e-107 357.9 0.8 6.5e-106 354.0 0.0 3.1 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORY99009.1 - 9.3e-19 67.8 12.8 1e-16 61.2 0.0 4.6 5 1 0 5 5 5 2 Microtubule binding Pox_A_type_inc PF04508.12 ORY99009.1 - 0.12 12.2 13.0 4.9 7.2 0.1 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat zf-C2H2_4 PF13894.6 ORY99010.1 - 8.5e-12 44.9 42.8 0.0062 17.3 3.3 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 ORY99010.1 - 1.3e-08 35.0 26.2 0.0031 17.8 2.0 5.9 5 1 1 6 6 6 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 ORY99010.1 - 8.8e-05 22.7 27.1 0.0059 16.9 4.9 4.4 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 ORY99010.1 - 0.00012 22.3 41.9 0.071 13.6 1.6 6.5 5 1 1 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY99010.1 - 0.00037 20.8 36.3 0.11 13.0 0.9 7.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY99010.1 - 0.0051 17.1 25.1 0.012 15.8 0.0 5.7 5 1 1 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY99010.1 - 0.05 13.6 0.6 0.05 13.6 0.6 6.7 6 2 2 8 8 8 0 C2H2-type zinc finger zf-HIT PF04438.16 ORY99010.1 - 0.091 12.7 1.1 0.091 12.7 1.1 4.5 6 0 0 6 6 6 0 HIT zinc finger zf-C2H2_3rep PF18868.1 ORY99010.1 - 0.34 11.6 16.6 0.085 13.5 2.1 3.5 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats C1_4 PF07975.12 ORY99010.1 - 0.4 10.9 0.1 0.4 10.9 0.1 4.5 2 1 3 5 5 5 0 TFIIH C1-like domain Lar_restr_allev PF14354.6 ORY99010.1 - 0.6 10.5 7.1 2.1 8.8 0.3 3.3 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-C2HC5 PF06221.13 ORY99010.1 - 0.83 9.7 0.1 0.83 9.7 0.1 4.3 5 1 0 5 5 5 0 Putative zinc finger motif, C2HC5-type Prok-RING_2 PF14445.6 ORY99010.1 - 1.3 9.2 14.9 12 6.2 0.0 4.5 4 1 0 4 4 4 0 Prokaryotic RING finger family 2 Zn-ribbon_8 PF09723.10 ORY99010.1 - 1.4 9.1 17.2 2.4 8.4 0.9 4.0 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 ORY99010.1 - 2 8.4 30.4 2.2 8.3 1.2 6.1 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 ORY99010.1 - 2.2 8.7 27.2 85 3.6 11.8 5.0 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 ORY99010.1 - 2.8 8.0 15.1 0.31 11.1 0.5 4.8 4 1 1 5 5 5 0 Sec23/Sec24 zinc finger Rad50_zn_hook PF04423.14 ORY99010.1 - 4 7.3 14.2 2.1 8.3 0.1 4.2 5 0 0 5 5 4 0 Rad50 zinc hook motif GCFC PF07842.12 ORY99011.1 - 5.7e-08 32.7 0.2 4.2e-07 29.9 0.1 2.4 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein Fib_alpha PF08702.10 ORY99011.1 - 0.041 14.1 2.7 0.2 11.8 0.5 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DNA_pack_N PF02500.15 ORY99011.1 - 0.18 11.6 1.3 1.3 8.8 0.2 2.3 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Tim44 PF04280.15 ORY99012.1 - 1.5e-17 64.1 0.0 1.7e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 ORY99012.1 - 0.00025 20.2 0.0 0.00028 20.0 0.0 1.0 1 0 0 1 1 1 1 MBA1-like protein Oxidored_q6 PF01058.22 ORY99013.1 - 2e-22 79.4 0.1 3.6e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ThrE PF06738.12 ORY99014.1 - 9.1e-30 103.8 20.2 6.7e-25 87.8 6.3 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY99014.1 - 4.2e-11 43.1 27.8 2.6e-08 34.0 7.2 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Peptidase_S10 PF00450.22 ORY99015.1 - 1.8e-112 376.8 0.4 2.3e-112 376.5 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 ORY99016.1 - 3.8e-120 402.1 1.2 4.7e-120 401.8 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GATA PF00320.27 ORY99017.1 - 2.3e-17 62.3 4.6 3.3e-17 61.8 4.6 1.3 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY99017.1 - 0.0011 18.4 2.0 0.0016 17.9 2.0 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY99017.1 - 0.016 15.3 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORY99017.1 - 0.036 14.2 0.8 0.05 13.8 0.8 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 ORY99017.1 - 0.18 11.9 3.2 1.8 8.7 3.7 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-dskA_traR PF01258.17 ORY99017.1 - 0.52 10.3 2.6 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger PPR_2 PF13041.6 ORY99018.1 - 3.7e-31 107.1 10.5 2.4e-12 46.9 0.0 6.6 3 3 4 7 7 7 4 PPR repeat family PPR PF01535.20 ORY99018.1 - 1.8e-25 87.4 11.7 0.0015 18.6 0.0 7.1 8 0 0 8 8 8 6 PPR repeat PPR_3 PF13812.6 ORY99018.1 - 1.9e-25 88.7 2.6 5.4e-07 29.6 0.0 5.1 2 2 3 5 5 5 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY99018.1 - 7.7e-16 57.5 0.1 0.00013 21.6 0.0 6.8 7 1 0 7 7 7 4 PPR repeat PPR_long PF17177.4 ORY99018.1 - 6.9e-11 41.9 0.4 0.0014 18.1 0.1 4.1 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP Wzy_C_2 PF11846.8 ORY99018.1 - 6.5e-05 22.9 1.2 0.17 11.8 0.4 2.8 2 0 0 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_14 PF13428.6 ORY99018.1 - 0.0034 18.1 2.7 7.5 7.7 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 ORY99018.1 - 0.27 11.7 6.5 6.6 7.2 0.0 3.4 4 0 0 4 4 4 0 Bacterial transcriptional activator domain RicinB_lectin_2 PF14200.6 ORY99019.1 - 1.6e-20 73.6 0.1 4.9e-10 40.0 0.0 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ORY99019.1 - 1.2e-12 48.2 0.0 3.9e-09 36.8 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Gal_GalNac_35kD PF17337.2 ORY99019.1 - 3.9e-05 23.8 0.1 0.056 13.5 0.0 2.5 1 1 2 3 3 3 2 Galactose-inhibitable lectin 35 kDa subunit LOR PF04525.12 ORY99019.1 - 0.079 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 LURP-one-related WD40 PF00400.32 ORY99020.1 - 2.9e-06 27.9 19.0 0.048 14.5 2.8 6.9 7 1 0 7 7 7 2 WD domain, G-beta repeat Dynein_IC2 PF11540.8 ORY99020.1 - 4.9e-05 23.2 0.4 0.00012 21.9 0.4 1.7 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 DUF5401 PF17380.2 ORY99020.1 - 0.00035 18.8 4.5 0.00035 18.8 4.5 2.5 3 0 0 3 3 3 1 Family of unknown function (DUF5401) ANAPC4_WD40 PF12894.7 ORY99020.1 - 0.042 14.1 0.2 0.83 10.0 0.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain LRIF1 PF15741.5 ORY99020.1 - 2.5 6.5 6.5 4.6 5.6 6.5 1.4 1 1 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 NPIP PF06409.11 ORY99020.1 - 3.6 6.6 6.5 6.9 5.6 6.5 1.4 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DUF4355 PF14265.6 ORY99020.1 - 5.5 7.2 20.8 1.7 8.9 9.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Ribosomal_L26 PF16906.5 ORY99021.1 - 7.8e-38 128.8 3.3 1e-37 128.5 3.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY99021.1 - 6.4e-08 32.3 3.1 1.4e-07 31.2 3.1 1.6 1 0 0 1 1 1 1 KOW motif DUF1495 PF07381.11 ORY99021.1 - 0.0051 16.6 0.1 0.0095 15.7 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) ADH_N PF08240.12 ORY99023.1 - 3.3e-28 97.7 0.5 5.7e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ORY99023.1 - 0.0094 15.5 0.0 0.056 12.9 0.0 2.3 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 ORY99023.1 - 0.04 13.8 1.3 0.2 11.6 0.4 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated DUF2461 PF09365.10 ORY99024.1 - 1.8e-60 204.4 0.0 3.5e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Tim54 PF11711.8 ORY99024.1 - 0.097 11.4 6.9 0.13 11.0 6.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 ORY99024.1 - 0.22 9.8 9.2 0.26 9.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 ORY99024.1 - 0.27 10.4 4.9 0.37 9.9 4.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2151 PF10221.9 ORY99024.1 - 0.37 9.3 9.2 0.51 8.9 9.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DNA_pol_phi PF04931.13 ORY99024.1 - 0.42 8.7 13.4 0.56 8.2 13.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi SURF2 PF05477.11 ORY99024.1 - 0.45 10.2 13.2 0.66 9.6 13.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF913 PF06025.12 ORY99024.1 - 0.52 9.2 5.2 0.79 8.6 5.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 ORY99024.1 - 0.74 9.0 4.5 0.89 8.7 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 ORY99024.1 - 1.1 9.0 11.2 1.7 8.4 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 ORY99024.1 - 2 7.1 12.4 3.1 6.5 12.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 ORY99024.1 - 3.9 5.8 11.1 5.4 5.3 11.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RXT2_N PF08595.11 ORY99024.1 - 5.7 6.9 12.4 13 5.7 12.4 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Alpha-L-AF_C PF06964.12 ORY99025.1 - 8.1e-27 94.4 1.8 8.6e-27 94.3 0.5 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 ORY99025.1 - 0.00037 20.8 0.1 0.00037 20.8 0.1 2.6 3 0 0 3 3 3 1 Carbohydrate binding domain Flavin_Reduct PF01613.18 ORY99025.1 - 0.034 14.2 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 Flavin reductase like domain Alpha-L-AF_C PF06964.12 ORY99026.1 - 1.1e-15 58.2 2.4 2e-12 47.6 2.4 2.5 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 ORY99026.1 - 0.00017 21.9 0.8 0.00017 21.9 0.8 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain CorA PF01544.18 ORY99028.1 - 0.13 11.6 11.0 1 8.6 11.0 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein EspB PF05802.11 ORY99028.1 - 0.31 11.0 3.0 2.4 8.1 0.3 2.3 1 1 1 2 2 2 0 Enterobacterial EspB protein Actin PF00022.19 ORY99029.1 - 7.4e-45 153.3 0.0 1.8e-43 148.7 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY99029.1 - 0.018 13.9 0.1 0.032 13.0 0.1 1.3 1 0 0 1 1 1 0 MreB/Mbl protein MFS_1 PF07690.16 ORY99030.1 - 1.2e-43 149.5 40.6 1.6e-41 142.4 42.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY99030.1 - 4.1e-13 48.6 16.2 4.1e-13 48.6 16.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY99030.1 - 2.3e-12 46.6 6.1 2.3e-12 46.6 6.1 3.8 2 1 2 4 4 4 1 Sugar (and other) transporter Complex1_LYR PF05347.15 ORY99031.1 - 1.5e-15 56.9 3.4 1.8e-15 56.7 3.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY99031.1 - 1.9e-06 28.5 1.1 2.4e-06 28.2 1.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 ORY99031.1 - 0.022 15.3 2.5 0.083 13.5 2.5 1.7 1 1 0 1 1 1 0 Complex1_LYR-like CX9C PF16860.5 ORY99032.1 - 1.9e-22 79.0 20.7 1.9e-13 50.2 7.3 2.4 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 ORY99032.1 - 0.0002 21.4 12.9 0.15 12.2 1.1 3.5 1 1 3 4 4 4 4 CHCH domain UCR_hinge PF02320.16 ORY99032.1 - 0.002 18.3 15.8 0.03 14.5 3.8 2.4 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 ORY99032.1 - 0.028 14.4 18.6 0.092 12.8 4.0 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 ORY99032.1 - 0.087 13.2 12.1 0.15 12.5 3.2 2.9 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 ORY99032.1 - 0.18 12.1 16.5 0.27 11.5 3.8 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 ORY99032.1 - 0.52 10.6 15.1 0.37 11.1 3.4 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 ORY99032.1 - 4.3 7.7 17.1 7.3 6.9 2.3 3.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Nuf2 PF03800.14 ORY99033.1 - 3.2e-15 56.5 7.6 2.2e-07 31.0 0.0 3.4 3 2 1 4 4 4 2 Nuf2 family BLOC1_2 PF10046.9 ORY99033.1 - 0.039 14.3 27.3 0.044 14.1 4.5 3.7 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 ORY99033.1 - 0.14 12.6 10.4 33 5.0 0.5 4.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) ThiS PF02597.20 ORY99033.1 - 0.53 11.0 4.6 1.2 9.8 0.3 3.2 2 1 1 3 3 3 0 ThiS family DASH_Dam1 PF08653.10 ORY99033.1 - 1 9.2 8.9 6.9 6.6 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF1664 PF07889.12 ORY99033.1 - 3.1 7.8 20.7 0.41 10.7 2.4 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ORY99033.1 - 7.2 6.9 10.6 11 6.4 1.0 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) KASH_CCD PF14662.6 ORY99033.1 - 7.3 6.4 47.6 9.4 6.0 19.9 2.9 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DHHA1 PF02272.19 ORY99033.1 - 7.3 7.0 11.5 8.1 6.9 3.0 2.6 3 0 0 3 3 3 0 DHHA1 domain Homeodomain PF00046.29 ORY99034.1 - 6.2e-20 70.8 1.9 6.9e-20 70.6 0.3 2.0 2 0 0 2 2 2 1 Homeodomain TFIIA PF03153.13 ORY99034.1 - 0.0041 17.2 13.2 0.0041 17.2 13.2 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Homeobox_KN PF05920.11 ORY99034.1 - 0.017 15.0 0.2 0.072 13.0 0.1 2.2 2 0 0 2 2 2 0 Homeobox KN domain DUF3123 PF11321.8 ORY99034.1 - 0.079 13.6 6.3 1.7 9.3 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) GTP_EFTU PF00009.27 ORY99035.1 - 7.6e-64 214.8 0.1 1.1e-63 214.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY99035.1 - 1e-31 109.2 0.0 2.9e-31 107.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY99035.1 - 1.3e-20 73.2 0.0 2.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY99035.1 - 6.7e-16 58.4 0.1 1.6e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORY99035.1 - 1.7e-13 50.5 0.0 3.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORY99035.1 - 0.001 19.1 0.1 0.0022 18.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY99035.1 - 0.018 14.8 0.1 0.058 13.1 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L22e PF01776.17 ORY99037.1 - 3.5e-48 162.5 1.3 4.3e-48 162.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DNA_ligase_OB PF03120.16 ORY99037.1 - 0.0029 17.4 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain DUF2681 PF10883.8 ORY99038.1 - 0.013 15.8 1.4 0.013 15.8 1.4 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2681) Podoplanin PF05808.11 ORY99038.1 - 0.015 15.4 3.6 0.042 13.9 3.4 1.9 1 1 0 1 1 1 0 Podoplanin DUF1180 PF06679.12 ORY99038.1 - 0.02 15.3 3.5 0.02 15.3 3.5 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF1180) DUF2370 PF10176.9 ORY99038.1 - 0.035 13.7 0.1 0.035 13.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2370) EphA2_TM PF14575.6 ORY99038.1 - 0.49 11.3 0.0 0.49 11.3 0.0 4.1 3 2 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain COX14 PF14880.6 ORY99038.1 - 0.75 9.7 1.9 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly FHIPEP PF00771.20 ORY99038.1 - 0.84 8.0 5.2 0.12 10.8 0.2 1.8 2 0 0 2 2 2 0 FHIPEP family Plasmodium_Vir PF05795.11 ORY99038.1 - 1.2 8.4 6.9 2.3 7.6 6.5 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Orf78 PF06024.12 ORY99038.1 - 1.6 9.1 8.7 6 7.2 0.5 3.5 2 1 1 3 3 3 0 Orf78 (ac78) V-ATPase_G PF03179.15 ORY99038.1 - 3.5 8.2 12.9 0.36 11.4 4.4 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit START PF01852.19 ORY99039.1 - 7.5e-13 48.4 0.2 2e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 START domain zf-MYND PF01753.18 ORY99040.1 - 1.6e-05 24.9 13.9 4.2e-05 23.5 13.9 1.8 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 ORY99040.1 - 0.26 9.1 3.8 0.21 9.4 3.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SR-25 PF10500.9 ORY99040.1 - 1.6 8.3 14.6 1.9 8.0 6.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pet127 PF08634.10 ORY99041.1 - 8.3e-100 333.7 5.3 1.2e-99 333.2 5.3 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 adh_short_C2 PF13561.6 ORY99043.1 - 2.1e-62 210.7 4.5 2.5e-62 210.5 4.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY99043.1 - 1.7e-54 184.2 3.0 2.1e-54 184.0 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY99043.1 - 4.2e-12 46.3 1.1 6e-12 45.8 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY99043.1 - 0.00071 19.1 0.6 0.0016 18.0 0.6 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY99043.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF768 PF05589.11 ORY99043.1 - 0.13 12.3 0.2 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF768) Peptidase_S8 PF00082.22 ORY99044.1 - 3.2e-78 263.0 0.0 5.5e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 ORY99044.1 - 8.6e-46 155.8 0.0 1.4e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II PseudoU_synth_1 PF01416.20 ORY99045.1 - 1.4e-11 44.8 0.0 5.4e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase MFS_1 PF07690.16 ORY99046.1 - 2.2e-20 72.9 44.0 5.7e-19 68.2 15.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY99046.1 - 4e-06 26.0 3.5 4e-06 26.0 3.5 2.8 2 1 1 3 3 3 1 MFS_1 like family Sugar_tr PF00083.24 ORY99046.1 - 1.3e-05 24.2 31.0 3.8e-05 22.7 31.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORY99046.1 - 7.2e-05 21.4 4.0 7.2e-05 21.4 4.0 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1479 PF07350.12 ORY99047.1 - 1.4e-137 458.9 0.0 1.7e-137 458.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 ORY99047.1 - 3.4e-07 30.7 0.0 8.3e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CSD PF00313.22 ORY99048.1 - 2.5e-18 65.7 0.2 2.4e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain KH_8 PF17903.1 ORY99049.1 - 1.8e-31 108.1 0.2 4.5e-31 106.8 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 ORY99049.1 - 0.012 15.4 0.0 0.047 13.5 0.0 1.9 2 0 0 2 2 2 0 KH domain Pfg27 PF09216.10 ORY99049.1 - 0.094 12.5 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Pfg27 DUF4381 PF14316.6 ORY99051.1 - 0.033 14.4 1.2 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NifQ PF04891.12 ORY99051.1 - 0.045 14.1 2.1 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 NifQ Stevor PF17410.2 ORY99051.1 - 0.3 10.6 3.7 0.71 9.4 3.7 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4083 PF13314.6 ORY99051.1 - 6.4 6.8 9.2 0.17 11.9 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) ABATE PF07336.11 ORY99051.1 - 9 7.0 8.4 4.7 7.9 1.5 3.1 3 1 1 4 4 4 0 Putative stress-induced transcription regulator Myosin_head PF00063.21 ORY99052.1 - 1e-269 896.4 0.3 1e-269 896.4 0.3 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 ORY99052.1 - 1.4e-26 92.8 2.8 1.4e-26 92.8 2.8 3.8 3 1 0 3 3 3 1 DIL domain IQ PF00612.27 ORY99052.1 - 2e-10 39.5 44.1 6.4e-06 25.5 1.5 7.7 8 0 0 8 8 8 4 IQ calmodulin-binding motif ZapB PF06005.12 ORY99052.1 - 0.009 16.4 8.9 0.009 16.4 8.9 4.9 3 1 1 4 4 4 1 Cell division protein ZapB AAA_22 PF13401.6 ORY99052.1 - 0.01 16.1 1.4 0.039 14.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ORY99052.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.2 2 1 0 2 2 1 0 AAA ATPase domain DUF1664 PF07889.12 ORY99052.1 - 0.28 11.2 8.7 0.048 13.7 0.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 ORY99052.1 - 0.42 10.8 13.2 0.13 12.5 7.3 3.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 ORY99052.1 - 0.58 10.3 10.3 3.9 7.7 0.9 4.2 2 1 1 3 3 3 0 bZIP transcription factor DUF724 PF05266.14 ORY99052.1 - 3.5 7.4 18.3 2 8.2 3.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 ORY99052.1 - 6.6 7.4 19.4 0.04 14.6 3.2 3.4 2 1 1 3 3 2 0 Initiation control protein YabA PIN_9 PF18477.1 ORY99052.1 - 8.7 6.7 10.4 1.5 9.1 4.6 2.6 2 0 0 2 2 2 0 PIN like domain Pkinase PF00069.25 ORY99053.1 - 1.6e-65 221.1 0.0 1.9e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99053.1 - 9.6e-25 87.3 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY99053.1 - 1.8e-06 27.5 0.0 1.6e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY99053.1 - 0.012 15.5 0.3 0.056 13.3 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY99053.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY99053.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY99055.1 - 4.2e-73 246.0 0.9 4.7e-73 245.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99055.1 - 6.6e-51 173.1 0.0 1.2e-50 172.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY99055.1 - 1.2e-22 80.0 2.2 1.4e-22 79.8 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 ORY99055.1 - 4e-06 26.4 0.0 7.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY99055.1 - 0.034 14.1 0.1 1.7 8.5 0.4 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY99055.1 - 0.049 13.0 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY99055.1 - 0.094 12.3 0.0 0.094 12.3 0.0 2.4 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DSHCT PF08148.12 ORY99055.1 - 0.27 10.9 1.7 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain Na_trans_assoc PF06512.13 ORY99055.1 - 0.8 9.9 12.0 2 8.7 12.0 1.7 1 0 0 1 1 1 0 Sodium ion transport-associated Haspin_kinase PF12330.8 ORY99055.1 - 6.3 5.6 12.3 0.072 12.0 2.7 2.4 2 1 0 2 2 2 0 Haspin like kinase domain Usp PF00582.26 ORY99056.1 - 2e-22 80.2 0.1 1.1e-21 77.8 0.1 1.8 1 1 0 1 1 1 1 Universal stress protein family Pkinase PF00069.25 ORY99057.1 - 6e-52 176.6 0.4 3.2e-51 174.2 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99057.1 - 7.8e-23 81.1 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY99057.1 - 0.0024 17.8 0.8 0.0038 17.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY99057.1 - 0.0099 15.5 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 ORY99057.1 - 0.06 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Longin PF13774.6 ORY99058.1 - 2.6e-28 97.9 0.0 4e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 ORY99058.1 - 8.2e-15 54.4 0.0 1.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Imm70 PF15601.6 ORY99058.1 - 0.061 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 70 VanZ PF04892.12 ORY99059.1 - 6e-08 33.4 5.5 1.1e-07 32.6 5.5 1.5 1 1 0 1 1 1 1 VanZ like family DUF4173 PF13777.6 ORY99059.1 - 0.005 16.3 6.3 0.027 13.9 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4173) DUF2279 PF10043.9 ORY99059.1 - 0.011 16.5 0.1 0.019 15.7 0.1 1.4 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) DUF2070 PF09843.9 ORY99059.1 - 0.012 13.9 1.8 0.014 13.7 1.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MMPL PF03176.15 ORY99059.1 - 0.046 12.7 1.0 0.058 12.3 1.0 1.2 1 0 0 1 1 1 0 MMPL family Herpes_gE PF02480.16 ORY99059.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SieB PF14163.6 ORY99059.1 - 0.41 10.1 2.3 0.73 9.3 2.3 1.5 1 1 0 1 1 1 0 Super-infection exclusion protein B Rhomboid PF01694.22 ORY99059.1 - 1.2 9.2 8.1 1.7 8.6 8.1 1.2 1 0 0 1 1 1 0 Rhomboid family YfhO PF09586.10 ORY99059.1 - 1.7 6.8 5.6 2 6.6 5.6 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ACT_7 PF13840.6 ORY99060.1 - 1.7e-29 101.4 0.0 7.4e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 ORY99060.1 - 1.5e-08 34.4 0.4 0.0027 17.5 0.1 2.4 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain DUF1281 PF06924.11 ORY99062.1 - 0.044 13.3 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) TAXi_C PF14541.6 ORY99062.1 - 0.061 13.1 1.8 0.079 12.7 1.8 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Y_phosphatase2 PF03162.13 ORY99063.1 - 2.3e-39 134.6 0.0 2.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY99063.1 - 0.0017 18.0 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY99063.1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family NFACT-R_1 PF05670.13 ORY99064.1 - 1.2e-41 141.8 0.2 2.4e-41 140.8 0.0 1.6 2 0 0 2 2 2 1 NFACT protein RNA binding domain Allexi_40kDa PF05549.11 ORY99064.1 - 0.49 9.9 3.6 0.7 9.4 3.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Paramyxo_ncap PF00973.19 ORY99064.1 - 1.9 7.3 8.0 2.5 6.9 8.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Rieske PF00355.26 ORY99065.1 - 2.4e-05 24.2 0.0 0.00015 21.6 0.0 2.1 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain DUF2981 PF11200.8 ORY99065.1 - 0.71 9.6 5.4 0.9 9.2 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Cytomega_UL84 PF06284.11 ORY99065.1 - 0.83 8.0 6.3 1.3 7.4 6.3 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Neur_chan_memb PF02932.16 ORY99065.1 - 1 9.4 2.9 1.3 9.0 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.6 ORY99065.1 - 1.1 9.4 6.5 1.4 9.0 6.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Sec62 PF03839.16 ORY99065.1 - 7.3 6.0 9.7 10 5.6 9.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 ORY99065.1 - 8.1 5.1 7.3 10 4.8 7.3 1.1 1 0 0 1 1 1 0 Presenilin GSH_synth_ATP PF03917.17 ORY99066.1 - 4.1e-134 447.1 0.0 4.8e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 ORY99066.1 - 5.4e-36 123.1 0.0 9.4e-36 122.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase zf-C2H2 PF00096.26 ORY99067.1 - 2.4e-12 46.6 18.5 1.4e-06 28.4 1.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY99067.1 - 1.4e-08 34.9 14.5 6e-05 23.5 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY99067.1 - 6.3e-07 29.5 14.2 1e-06 28.9 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 ORY99067.1 - 5.3e-05 23.8 3.9 0.13 12.9 0.8 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 ORY99067.1 - 0.0008 19.7 2.6 0.69 10.4 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 ORY99067.1 - 0.0014 18.5 1.1 0.35 10.9 0.0 2.1 1 1 1 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.6 ORY99067.1 - 0.0029 17.6 1.7 0.0029 17.6 1.7 3.0 2 2 0 2 2 2 1 C2H2-type zinc finger zf-LYAR PF08790.11 ORY99067.1 - 0.0071 16.2 0.8 2.9 7.9 0.1 2.5 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 ORY99067.1 - 0.0073 16.6 2.3 8.1 6.8 0.6 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY99067.1 - 0.022 14.9 3.9 0.11 12.6 3.9 1.8 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORY99067.1 - 0.022 15.0 0.8 0.022 15.0 0.8 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 ORY99067.1 - 0.15 12.8 4.9 0.4 11.4 0.8 2.0 1 1 1 2 2 2 0 CHORD zf-C2H2_2 PF12756.7 ORY99067.1 - 0.2 12.0 7.6 1.7 9.0 0.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORY99067.1 - 0.36 10.6 22.9 1.1 9.0 3.7 3.7 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORY99067.1 - 0.55 10.7 11.9 1.9 9.0 2.0 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Bromodomain PF00439.25 ORY99069.1 - 1.8e-45 152.9 0.0 1.8e-22 79.2 0.0 2.7 2 0 0 2 2 2 2 Bromodomain Peptidase_M1 PF01433.20 ORY99069.1 - 0.0003 20.4 0.2 0.00073 19.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain HEAT_2 PF13646.6 ORY99069.1 - 0.0015 18.9 0.1 0.55 10.6 0.1 2.7 2 0 0 2 2 2 2 HEAT repeats RPA_interact_M PF14767.6 ORY99069.1 - 0.5 11.0 2.0 5.4 7.7 0.9 2.7 2 0 0 2 2 2 0 Replication protein A interacting middle Orai-1 PF07856.12 ORY99070.1 - 0.061 13.0 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF3043 PF11241.8 ORY99070.1 - 0.063 13.3 0.2 0.074 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) YrhC PF14143.6 ORY99070.1 - 0.23 11.6 0.9 0.33 11.1 0.9 1.3 1 0 0 1 1 1 0 YrhC-like protein Iso_dh PF00180.20 ORY99071.1 - 6.1e-83 278.8 0.0 7.3e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NUDE_C PF04880.13 ORY99072.1 - 3.3e-14 53.7 21.5 3.3e-14 53.7 21.5 3.0 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.8 ORY99072.1 - 0.0023 15.5 24.6 0.0029 15.2 24.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 ORY99072.1 - 0.0042 17.1 40.2 0.005 16.9 9.4 3.4 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein PSII_Pbs27 PF13326.6 ORY99072.1 - 0.018 15.4 3.1 0.018 15.4 3.1 2.2 2 1 0 2 2 2 0 Photosystem II Pbs27 ZapB PF06005.12 ORY99072.1 - 0.022 15.2 11.9 0.022 15.2 11.9 4.8 1 1 3 4 4 3 0 Cell division protein ZapB DUF4201 PF13870.6 ORY99072.1 - 0.047 13.4 32.1 0.076 12.7 7.8 3.3 1 1 0 3 3 3 0 Domain of unknown function (DUF4201) Noelin-1 PF12308.8 ORY99072.1 - 0.63 10.1 15.3 0.057 13.4 3.7 3.3 2 1 1 4 4 4 0 Neurogenesis glycoprotein LXG PF04740.12 ORY99072.1 - 0.72 9.5 24.4 0.24 11.1 2.7 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily Fib_alpha PF08702.10 ORY99072.1 - 0.97 9.6 24.4 0.12 12.5 10.4 2.6 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family DUF730 PF05325.11 ORY99072.1 - 1.1 9.3 8.3 0.52 10.3 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF730) GAS PF13851.6 ORY99072.1 - 1.1 8.6 36.7 0.19 11.0 12.1 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 ORY99072.1 - 1.1 10.2 34.3 0.52 11.2 11.6 4.0 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain TACC_C PF05010.14 ORY99072.1 - 1.2 8.9 31.6 5.6 6.7 17.5 2.9 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FPP PF05911.11 ORY99072.1 - 1.4 7.0 32.1 2.7 6.1 11.9 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF948 PF06103.11 ORY99072.1 - 1.6 9.1 8.1 8.5 6.7 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.8 ORY99072.1 - 1.9 8.7 34.7 15 5.9 8.4 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding KxDL PF10241.9 ORY99072.1 - 2.1 8.7 21.3 1.3 9.3 6.4 3.3 2 1 0 3 3 2 0 Uncharacterized conserved protein CENP-Q PF13094.6 ORY99072.1 - 3.6 7.8 33.9 20 5.4 11.0 3.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Mod_r PF07200.13 ORY99072.1 - 4.1 7.5 32.2 6.7 6.8 13.3 2.7 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 ORY99072.1 - 4.8 7.7 47.2 3.9 8.0 20.1 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region AATF-Che1 PF13339.6 ORY99072.1 - 5.9 7.6 25.5 1.1 10.0 9.0 2.7 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor CENP-F_leu_zip PF10473.9 ORY99072.1 - 6.7 6.7 39.5 3 7.9 8.7 4.7 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 ORY99072.1 - 8.5 4.8 15.1 0.52 8.8 3.0 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Spc7 PF08317.11 ORY99072.1 - 9 5.1 37.8 2.8 6.7 13.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Pkinase PF00069.25 ORY99073.1 - 8.2e-52 176.2 1.1 3.1e-51 174.3 1.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99073.1 - 6.1e-24 84.7 0.1 1.1e-23 83.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY99073.1 - 0.00042 19.2 0.1 0.0006 18.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 ORY99073.1 - 0.0013 18.3 1.0 0.024 14.2 0.0 2.3 1 1 1 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.11 ORY99073.1 - 0.0015 17.6 0.1 0.0024 16.9 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF2340 PF10209.9 ORY99073.1 - 0.12 12.8 0.3 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) Sybindin PF04099.12 ORY99074.1 - 5.2e-51 172.3 0.1 5.8e-51 172.2 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORY99074.1 - 5.2e-08 33.1 0.0 5.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FtsX PF02687.21 ORY99075.1 - 0.02 15.4 8.4 0.42 11.1 0.7 2.7 2 1 0 2 2 2 0 FtsX-like permease family DUF983 PF06170.12 ORY99075.1 - 0.23 11.9 0.3 0.23 11.9 0.3 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF983) COX6A PF02046.15 ORY99077.1 - 5.1e-27 94.6 5.4 5.5e-27 94.5 5.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Smg4_UPF3 PF03467.15 ORY99078.1 - 1.5e-56 191.2 0.7 1.5e-56 191.2 0.7 4.1 3 1 1 4 4 4 1 Smg-4/UPF3 family DDHD PF02862.17 ORY99078.1 - 0.25 11.4 0.0 0.25 11.4 0.0 3.2 2 1 0 2 2 2 0 DDHD domain Glyco_transf_15 PF01793.16 ORY99079.1 - 8e-79 265.2 7.1 9.2e-79 265.0 7.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5565 PF17720.1 ORY99079.1 - 0.1 11.4 0.1 0.24 10.2 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5565) Dynactin_p22 PF07426.11 ORY99080.1 - 1.5e-39 135.5 4.9 2.1e-39 135.1 4.9 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Sec3_C PF09763.9 ORY99080.1 - 0.00036 19.1 1.5 0.00044 18.8 0.2 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec3 Bacillus_HBL PF05791.11 ORY99080.1 - 0.0023 17.8 3.5 0.049 13.5 0.6 2.2 1 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DASH_Dad2 PF08654.10 ORY99080.1 - 0.0025 18.2 2.5 1.7 9.1 0.0 2.7 1 1 0 2 2 2 2 DASH complex subunit Dad2 NPV_P10 PF05531.12 ORY99080.1 - 0.0035 17.8 1.2 1.8 9.1 0.0 2.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 ORY99080.1 - 0.0098 16.1 3.9 0.76 10.0 0.1 3.3 3 0 0 3 3 3 1 Haemolysin XhlA FliJ PF02050.16 ORY99080.1 - 0.012 15.8 3.8 0.77 10.0 0.7 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein GIT_CC PF16559.5 ORY99080.1 - 0.018 14.9 2.0 0.026 14.4 0.2 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4262 PF14081.6 ORY99080.1 - 0.022 14.9 0.3 0.086 13.1 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4262) APG6_N PF17675.1 ORY99080.1 - 0.026 15.1 8.9 0.068 13.7 8.7 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 ORY99080.1 - 0.04 13.6 7.4 0.88 9.2 7.4 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 ORY99080.1 - 0.045 14.1 2.0 22 5.5 0.0 3.6 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) Mer2 PF09074.10 ORY99080.1 - 0.047 13.5 2.9 0.06 13.2 2.9 1.2 1 0 0 1 1 1 0 Mer2 IL11 PF07400.11 ORY99080.1 - 0.048 13.3 1.2 0.19 11.3 0.1 2.1 1 1 0 2 2 2 0 Interleukin 11 CLZ PF16526.5 ORY99080.1 - 0.053 13.9 7.4 0.36 11.2 0.9 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mod_r PF07200.13 ORY99080.1 - 0.055 13.6 8.4 0.022 14.8 2.9 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Vac_Fusion PF02346.16 ORY99080.1 - 0.061 13.0 3.9 1.5 8.5 0.7 3.3 2 2 2 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 TolA_bind_tri PF16331.5 ORY99080.1 - 0.064 13.3 5.4 0.62 10.2 0.1 2.9 2 1 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 ORY99080.1 - 0.081 13.5 6.4 4.3 8.0 1.0 3.1 2 1 1 3 3 3 0 SlyX NYD-SP28 PF14772.6 ORY99080.1 - 0.083 12.9 3.7 0.11 12.5 0.8 2.2 1 1 1 2 2 2 0 Sperm tail GAS PF13851.6 ORY99080.1 - 0.1 12.0 7.7 2.1 7.6 7.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 ORY99080.1 - 0.1 13.1 2.8 1.5 9.3 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Apt1 PF10351.9 ORY99080.1 - 0.11 11.3 3.3 0.12 11.2 2.5 1.4 1 1 1 2 2 2 0 Golgi-body localisation protein domain STAT_alpha PF01017.20 ORY99080.1 - 0.12 12.3 4.8 1.3 8.9 4.8 2.1 1 1 0 1 1 1 0 STAT protein, all-alpha domain Fib_alpha PF08702.10 ORY99080.1 - 0.15 12.2 4.8 3.3 7.9 0.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Zwint PF15556.6 ORY99080.1 - 0.15 11.5 4.8 0.062 12.8 0.9 1.9 1 1 1 2 2 2 0 ZW10 interactor DASH_Duo1 PF08651.10 ORY99080.1 - 0.16 11.8 2.1 13 5.7 0.3 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 RNA_polI_A14 PF08203.11 ORY99080.1 - 0.21 12.3 4.4 5 7.9 0.1 3.0 4 1 0 4 4 3 0 Yeast RNA polymerase I subunit RPA14 DUF1664 PF07889.12 ORY99080.1 - 0.25 11.4 4.4 2.2 8.4 0.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 ORY99080.1 - 0.29 11.2 4.5 0.26 11.4 0.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapD PF07072.11 ORY99080.1 - 0.3 10.8 4.7 0.78 9.5 0.3 2.4 1 1 2 3 3 3 0 Cell division protein HIP1_clath_bdg PF16515.5 ORY99080.1 - 0.31 11.7 5.9 6.7 7.4 1.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MitMem_reg PF13012.6 ORY99080.1 - 0.39 11.2 5.3 7.5 7.0 5.3 2.2 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Prefoldin_2 PF01920.20 ORY99080.1 - 0.75 9.8 7.1 1.6 8.7 0.2 3.0 2 1 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 ORY99080.1 - 1.5 7.4 4.5 1.7 7.1 1.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A ZapB PF06005.12 ORY99080.1 - 3.1 8.3 7.7 16 6.1 2.4 2.6 2 1 0 2 2 2 0 Cell division protein ZapB TPR_12 PF13424.6 ORY99081.1 - 0.0088 16.3 1.1 0.98 9.8 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_8 PF13855.6 ORY99082.1 - 0.0063 16.2 3.1 0.16 11.8 0.4 2.6 2 0 0 2 2 2 2 Leucine rich repeat PilN PF05137.13 ORY99082.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) DUF4110 PF13422.6 ORY99082.1 - 0.12 12.5 4.3 0.14 12.2 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) LRR_4 PF12799.7 ORY99082.1 - 0.13 12.8 1.8 5.3 7.6 0.3 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) CotH PF08757.11 ORY99083.1 - 8.9e-31 107.6 4.7 1.2e-30 107.1 4.7 1.1 1 0 0 1 1 1 1 CotH kinase protein RRM_1 PF00076.22 ORY99084.1 - 1.9e-41 139.7 0.0 2.1e-16 59.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY99084.1 - 0.00064 19.7 0.0 0.0031 17.5 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY99084.1 - 0.0022 17.6 0.0 0.018 14.7 0.0 2.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY99084.1 - 0.0025 17.9 0.0 0.032 14.3 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 ORY99084.1 - 0.045 13.8 0.0 0.16 12.0 0.0 1.9 3 0 0 3 3 3 0 RNA binding motif HA2 PF04408.23 ORY99085.1 - 1.7e-21 76.5 4.3 6.1e-21 74.7 0.0 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY99085.1 - 6.4e-17 61.7 0.0 1.5e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY99085.1 - 2.3e-10 40.8 0.0 3.6e-08 33.7 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY99085.1 - 8.8e-09 35.4 0.2 1.8e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY99085.1 - 6.5e-07 29.7 0.0 2.2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY99085.1 - 0.00083 19.4 0.1 0.0054 16.7 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 ORY99085.1 - 0.0024 17.2 0.0 0.0063 15.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 ORY99085.1 - 0.0029 17.0 0.0 0.0076 15.6 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 ORY99085.1 - 0.0069 16.7 0.1 0.019 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY99085.1 - 0.013 14.5 2.3 0.031 13.3 2.3 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein RNA_pol_3_Rpc31 PF11705.8 ORY99085.1 - 0.014 15.7 4.8 0.014 15.7 4.8 2.8 2 1 0 2 2 1 0 DNA-directed RNA polymerase III subunit Rpc31 PhoH PF02562.16 ORY99085.1 - 0.053 13.0 0.3 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 ORY99085.1 - 0.13 12.8 0.0 0.13 12.8 0.0 3.2 3 1 0 3 3 2 0 AAA domain DUF1688 PF07958.11 ORY99086.1 - 2.6e-145 484.4 0.0 2.9e-145 484.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 ORY99086.1 - 0.0043 16.7 0.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family Ran-binding PF05508.11 ORY99087.1 - 4.6e-48 163.8 4.8 3.4e-46 157.7 4.8 2.2 1 1 0 1 1 1 1 RanGTP-binding protein DASH_Spc19 PF08287.11 ORY99087.1 - 0.025 14.4 8.6 0.093 12.6 0.1 2.9 2 1 0 2 2 2 0 Spc19 E7 PF00527.18 ORY99087.1 - 0.027 14.7 4.8 2.7 8.3 1.9 2.9 2 0 0 2 2 2 0 E7 protein, Early protein GEN1_C PF18380.1 ORY99087.1 - 0.033 15.1 3.3 0.084 13.8 3.3 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Rogdi_lz PF10259.9 ORY99087.1 - 0.047 13.1 1.3 0.076 12.5 1.3 1.4 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Sigma70_ner PF04546.13 ORY99087.1 - 0.77 9.6 10.3 4.3 7.2 5.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region F-box-like PF12937.7 ORY99088.1 - 0.0029 17.5 0.5 0.0067 16.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 ORY99089.1 - 0.037 13.9 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ORY99089.1 - 0.057 13.3 1.8 0.15 12.0 0.0 2.8 3 0 0 3 3 3 0 F-box domain CRM1_C PF08767.11 ORY99090.1 - 3.4e-28 98.8 1.3 1.3e-27 96.9 0.1 2.6 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 ORY99090.1 - 9.7e-24 84.1 0.8 3.1e-22 79.2 0.7 3.2 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 ORY99090.1 - 1e-10 41.1 0.1 4.3e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 ORY99090.1 - 9.9e-09 35.0 0.7 9.9e-09 35.0 0.7 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 ORY99090.1 - 3.2e-07 29.7 2.8 7.9e-07 28.5 2.8 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat CRM1_repeat_3 PF18787.1 ORY99090.1 - 0.01 15.9 0.0 0.035 14.2 0.0 1.9 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 PDZ_3 PF17815.1 ORY99090.1 - 0.077 12.9 0.2 0.95 9.3 0.0 2.8 3 0 0 3 3 3 0 PDZ domain FlbT PF07378.11 ORY99090.1 - 0.091 12.8 0.7 0.36 10.9 0.2 2.3 2 0 0 2 2 2 0 Flagellar protein FlbT AAA_lid_7 PF17867.1 ORY99090.1 - 0.096 12.9 0.4 37 4.6 0.1 3.5 3 0 0 3 3 3 0 Midasin AAA lid domain Arrestin_N PF00339.29 ORY99091.1 - 2e-08 34.4 0.1 1.9e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY99091.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Ferritin PF00210.24 ORY99092.1 - 6.6e-25 87.7 1.7 7.8e-25 87.5 1.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF1264 PF06884.11 ORY99093.1 - 3.9e-71 238.2 0.1 4.5e-71 237.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) WD40 PF00400.32 ORY99094.1 - 1.6e-17 63.6 24.5 0.00042 21.1 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY99094.1 - 2.6e-15 56.5 7.8 2.2e-06 27.8 0.4 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY99094.1 - 3.6e-10 39.3 0.4 1.3e-06 27.7 0.0 3.1 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY99094.1 - 2.9e-07 30.5 0.1 0.0071 16.2 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 ORY99094.1 - 0.0052 16.1 0.4 2.2 7.5 0.0 2.2 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 ORY99094.1 - 0.11 10.4 1.6 0.51 8.3 0.7 1.9 1 1 0 1 1 1 0 IKI3 family zf-C2H2 PF00096.26 ORY99095.1 - 3.5e-20 71.3 26.7 9.7e-06 25.8 1.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY99095.1 - 8.5e-18 63.9 20.3 1.4e-06 28.4 0.0 5.4 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY99095.1 - 1.6e-09 37.8 25.7 0.013 16.2 2.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 ORY99095.1 - 0.00067 20.0 13.8 1.5 9.3 1.4 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY99095.1 - 0.00096 19.4 13.2 0.43 10.9 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY99095.1 - 0.0012 19.5 5.1 0.025 15.2 0.8 4.9 2 1 3 5 5 5 2 FOXP coiled-coil domain zf-CGNR PF11706.8 ORY99095.1 - 2.7 7.9 10.2 19 5.2 1.3 3.4 3 1 0 3 3 3 0 CGNR zinc finger zf-C2HC_2 PF13913.6 ORY99095.1 - 3.5 7.6 6.9 9.1 6.3 0.3 3.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORY99095.1 - 8.2 6.3 15.7 14 5.5 1.5 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type JAB PF01398.21 ORY99098.1 - 2e-15 56.8 0.0 4.9e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HMG_box PF00505.19 ORY99099.1 - 3.4e-17 62.6 0.4 3.4e-17 62.6 0.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY99099.1 - 2.1e-12 47.4 0.3 4.4e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain NESP55 PF06390.12 ORY99099.1 - 0.00011 21.9 7.1 0.00011 21.9 7.1 1.7 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) Lin-8 PF03353.15 ORY99099.1 - 0.012 15.2 1.4 0.023 14.3 1.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist bZIP_1 PF00170.21 ORY99099.1 - 0.046 13.8 2.3 0.27 11.4 0.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor BRE1 PF08647.11 ORY99099.1 - 0.059 13.4 0.6 0.059 13.4 0.6 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 ORY99099.1 - 0.11 12.3 0.3 0.35 10.7 0.3 1.8 1 0 0 1 1 1 0 Septum formation initiator FapA PF03961.13 ORY99099.1 - 0.33 9.5 3.3 2.7 6.5 0.7 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A MRP-L47 PF06984.13 ORY99100.1 - 9.3e-28 96.2 0.6 1.4e-27 95.6 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 ORY99100.1 - 1.7e-07 31.1 0.5 4.4e-07 29.8 0.5 1.7 1 1 0 1 1 1 1 Ribosomal L29 protein DUF3328 PF11807.8 ORY99100.1 - 0.0096 15.7 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) G-alpha PF00503.20 ORY99101.1 - 6.4e-122 407.1 2.9 7.4e-122 406.9 2.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY99101.1 - 4.8e-16 58.7 3.6 1.1e-11 44.5 0.4 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY99101.1 - 0.00014 21.3 2.1 0.011 15.1 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY99101.1 - 0.0049 17.1 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY99101.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.20 ORY99101.1 - 0.028 14.2 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger MMR_HSR1 PF01926.23 ORY99101.1 - 0.064 13.3 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORY99101.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family IPPT PF01715.17 ORY99102.1 - 1.9e-68 230.7 0.7 3.5e-68 229.8 0.7 1.3 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 ORY99102.1 - 5.5e-05 23.7 0.0 0.048 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORY99102.1 - 0.00015 21.9 3.1 0.00096 19.3 0.0 3.4 2 2 0 2 2 2 1 AAA domain IPT PF01745.16 ORY99102.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase Hpr_kinase_C PF07475.12 ORY99102.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 ORY99102.1 - 0.026 14.9 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF4790 PF16037.5 ORY99102.1 - 0.036 14.5 0.1 1.6 9.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) Ploopntkinase3 PF18751.1 ORY99102.1 - 0.064 13.2 0.5 0.92 9.4 0.0 2.6 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 ORY99102.1 - 0.073 13.3 0.2 0.56 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 ORY99102.1 - 0.081 13.2 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 ORY99102.1 - 0.089 13.2 0.0 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY99102.1 - 0.13 12.7 0.3 0.52 10.8 0.0 2.1 3 0 0 3 3 2 0 ABC transporter AAA_5 PF07728.14 ORY99102.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 ORY99102.1 - 0.14 12.2 0.4 0.23 11.5 0.3 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HSF_DNA-bind PF00447.17 ORY99104.1 - 3e-31 107.9 0.9 4.3e-31 107.4 0.1 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Zwint PF15556.6 ORY99104.1 - 0.0051 16.3 0.4 0.0071 15.9 0.4 1.2 1 0 0 1 1 1 1 ZW10 interactor FlaC_arch PF05377.11 ORY99105.1 - 0.086 13.2 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Suf PF05843.14 ORY99105.1 - 0.28 11.1 13.9 0.57 10.1 2.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Peroxin-3 PF04882.12 ORY99105.1 - 3.7 6.4 13.1 6 5.7 0.5 2.1 2 0 0 2 2 2 0 Peroxin-3 STT3 PF02516.14 ORY99106.1 - 1.8e-151 505.4 32.4 4.3e-146 487.7 30.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit AP3D1 PF06375.11 ORY99106.1 - 0.11 12.7 6.4 0.99 9.6 0.1 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF4834 PF16118.5 ORY99106.1 - 1.5 9.8 4.8 1.8 9.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) GATase_5 PF13507.6 ORY99107.1 - 5e-106 353.6 0.0 7.5e-106 353.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 ORY99107.1 - 9.6e-49 165.5 6.6 4e-31 108.2 0.0 2.8 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 ORY99107.1 - 3.7e-32 110.7 0.0 7.5e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 ORY99107.1 - 1.3e-22 80.0 0.0 3.3e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 ORY99107.1 - 0.48 11.1 3.2 3.5 8.3 0.0 3.3 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain Y_Y_Y PF07495.13 ORY99108.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain DUF3425 PF11905.8 ORY99109.1 - 6e-11 42.4 1.7 3.2e-10 40.0 1.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) SLC3A2_N PF16028.5 ORY99111.1 - 0.046 13.3 1.1 0.071 12.7 1.1 1.2 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus zf-C2H2_4 PF13894.6 ORY99112.1 - 1e-05 25.9 65.1 0.039 14.8 1.7 8.9 8 1 1 9 9 9 6 C2H2-type zinc finger zf-met PF12874.7 ORY99112.1 - 0.00053 20.3 0.2 0.044 14.2 0.1 7.0 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY99112.1 - 0.02 15.2 0.1 0.02 15.2 0.1 6.6 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ORY99112.1 - 0.047 14.2 0.8 0.047 14.2 0.8 8.2 8 0 0 8 8 8 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY99112.1 - 0.057 13.4 1.0 0.057 13.4 1.0 7.7 8 2 2 10 10 10 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY99112.1 - 0.18 12.3 41.9 0.44 11.1 1.0 8.4 8 0 0 8 8 8 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 ORY99112.1 - 3.4 7.9 25.7 1.4 9.1 1.3 5.5 6 0 0 6 6 6 0 Zinc ribbon domain Zds_C PF08632.10 ORY99113.1 - 3.5e-21 74.7 0.8 7.5e-21 73.6 0.8 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term aGPT-Pplase2 PF18724.1 ORY99113.1 - 0.28 10.9 2.0 0.42 10.3 2.0 1.2 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 CorA PF01544.18 ORY99114.1 - 4.9e-45 154.1 2.6 2e-23 83.2 0.3 2.0 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein BTG PF07742.12 ORY99115.1 - 6.4e-32 109.8 0.0 1.2e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 BTG family Suf PF05843.14 ORY99115.1 - 0.037 14.0 15.9 0.058 13.4 15.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 ORY99115.1 - 0.062 13.3 1.9 0.057 13.5 1.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 ORY99115.1 - 0.49 10.3 27.0 0.59 10.1 27.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tau95_N PF17682.1 ORY99115.1 - 1 9.6 8.2 2.1 8.5 8.2 1.6 1 1 0 1 1 1 0 Tau95 Triple barrel domain RR_TM4-6 PF06459.12 ORY99115.1 - 1.2 8.9 9.1 1.5 8.6 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 ORY99115.1 - 1.4 8.5 29.0 2.3 7.8 29.0 1.5 1 0 0 1 1 1 0 Spt20 family BRO1 PF03097.18 ORY99117.1 - 1.4e-125 419.1 0.3 3.1e-125 418.0 0.3 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY99117.1 - 6.2e-63 212.8 18.1 6.2e-63 212.8 18.1 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Phage_lysozyme2 PF18013.1 ORY99117.1 - 0.19 11.8 1.8 0.71 9.9 1.8 2.0 1 0 0 1 1 1 0 Phage tail lysozyme Prominin PF05478.11 ORY99117.1 - 5.4 4.8 11.7 4.9 5.0 10.2 1.6 1 1 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 ORY99117.1 - 9.2 6.3 10.0 3.6 7.6 2.9 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DPBB_1 PF03330.18 ORY99118.1 - 3.2e-09 36.9 0.0 6.1e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY99118.1 - 0.0027 17.5 0.1 0.0033 17.2 0.1 1.2 1 0 0 1 1 1 1 Barwin family FOXP-CC PF16159.5 ORY99119.1 - 0.00054 20.5 0.8 0.00069 20.2 0.8 1.3 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 ORY99119.1 - 0.0097 16.3 1.5 0.018 15.5 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C3HC4_3 PF13920.6 ORY99120.1 - 9.6e-09 35.0 5.5 1.6e-08 34.2 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 ORY99120.1 - 1.1e-07 31.6 1.4 2.2e-07 30.6 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 ORY99120.1 - 2.8e-06 27.1 9.9 5.1e-06 26.2 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY99120.1 - 4.9e-06 26.4 9.7 8.8e-06 25.6 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY99120.1 - 6.2e-06 26.1 9.8 1.5e-05 24.9 9.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY99120.1 - 6.2e-06 26.0 10.6 1.2e-05 25.1 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 ORY99120.1 - 1.9e-05 24.5 2.6 3.6e-05 23.6 2.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 ORY99120.1 - 3.3e-05 24.1 8.3 6.3e-05 23.2 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 ORY99120.1 - 8.7e-05 22.6 4.0 8.7e-05 22.6 4.0 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 ORY99120.1 - 0.00045 20.3 8.1 0.0012 19.0 8.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY99120.1 - 0.00086 19.1 7.1 0.0016 18.2 7.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 ORY99120.1 - 0.0026 17.5 1.8 0.0026 17.5 1.8 2.0 2 0 0 2 2 1 1 CCCH-type zinc finger zf-Nse PF11789.8 ORY99120.1 - 0.14 12.0 2.5 0.25 11.2 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 ORY99120.1 - 0.34 10.8 3.4 0.67 9.9 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein GATA PF00320.27 ORY99121.1 - 8.7e-30 102.0 16.2 1.5e-15 56.4 5.0 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY99121.1 - 0.0037 16.7 6.9 0.35 10.4 1.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY99121.1 - 0.028 14.5 5.4 0.89 9.7 0.5 3.0 3 0 0 3 3 3 0 Zinc ribbon domain TDP43_N PF18694.1 ORY99121.1 - 0.034 14.0 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Cytochrome_C7 PF14522.6 ORY99121.1 - 0.057 13.4 0.8 0.057 13.4 0.8 3.0 3 0 0 3 3 3 0 Cytochrome c7 and related cytochrome c Vps36-NZF-N PF16988.5 ORY99121.1 - 0.14 11.5 2.7 0.23 10.9 0.1 2.7 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Auto_anti-p27 PF06677.12 ORY99121.1 - 0.68 10.1 13.2 0.23 11.7 1.3 3.5 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Spt20 PF12090.8 ORY99121.1 - 0.85 9.2 20.6 0.052 13.2 14.4 1.9 2 0 0 2 2 2 0 Spt20 family OrfB_Zn_ribbon PF07282.11 ORY99121.1 - 1.5 8.8 10.1 0.45 10.5 1.4 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain IRF-2BP1_2 PF11261.8 ORY99121.1 - 3.2 7.4 5.2 17 5.1 0.9 2.4 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger YnfE PF17452.2 ORY99122.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized YnfE-like zf-C2H2 PF00096.26 ORY99123.1 - 0.039 14.4 1.8 0.14 12.7 1.8 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type TFIIA PF03153.13 ORY99123.1 - 0.045 13.8 9.2 0.052 13.5 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY99123.1 - 0.079 12.6 12.4 0.11 12.1 12.4 1.2 1 0 0 1 1 1 0 Spt20 family Peptidase_M13_N PF05649.13 ORY99124.1 - 9.9e-69 232.8 0.0 1.3e-68 232.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY99124.1 - 1.3e-18 67.4 0.5 9.2e-09 35.2 0.3 3.2 1 1 1 2 2 2 2 Peptidase family M13 Sugar_tr PF00083.24 ORY99125.1 - 1.7e-112 376.6 17.1 1.9e-112 376.4 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY99125.1 - 1.3e-25 90.1 19.6 1.3e-25 90.1 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2383 PF09537.10 ORY99126.1 - 0.056 13.8 4.8 0.18 12.1 4.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) SNF2_N PF00176.23 ORY99127.1 - 7.3e-69 232.1 0.3 7.3e-69 232.1 0.3 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY99127.1 - 3.1e-19 69.4 0.1 1.1e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY99127.1 - 5.1e-12 46.1 0.5 1.2e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY99127.1 - 0.00028 20.7 0.0 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSM3_C PF18794.1 ORY99127.1 - 0.12 12.0 0.2 0.32 10.6 0.2 1.6 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain WD40 PF00400.32 ORY99128.1 - 3.9e-46 154.1 25.3 2.2e-09 37.7 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY99128.1 - 3.4e-10 40.1 1.8 0.16 12.3 0.0 4.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY99128.1 - 6.7e-07 28.6 0.0 0.36 9.7 0.0 4.0 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY99128.1 - 3.4e-06 27.1 0.3 0.00015 21.7 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ORY99128.1 - 0.00022 19.9 0.1 0.21 10.1 0.1 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 ORY99128.1 - 0.00036 19.3 8.4 0.0054 15.4 0.2 4.5 2 1 2 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 ORY99128.1 - 0.0013 18.6 0.2 11 6.1 0.1 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat HisG PF01634.18 ORY99129.1 - 8.4e-53 178.6 0.1 1.2e-52 178.1 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ORY99129.1 - 3.3e-24 84.8 0.6 7.3e-24 83.7 0.1 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 ORY99129.1 - 0.011 15.6 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 NMT1/THI5 like LysR_substrate PF03466.20 ORY99129.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain O-FucT PF10250.9 ORY99130.1 - 1e-15 58.3 0.0 9.5e-15 55.1 0.0 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Alpha_L_fucos PF01120.17 ORY99131.1 - 5.2e-85 286.0 4.5 7.4e-85 285.5 4.5 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase F_bP_aldolase PF01116.20 ORY99132.1 - 2.2e-91 306.2 0.0 2.5e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DEAD PF00270.29 ORY99133.1 - 5.4e-44 150.1 0.2 8.2e-44 149.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY99133.1 - 4.6e-33 113.9 0.4 2.5e-31 108.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY99133.1 - 2e-07 31.2 0.1 5.6e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY99133.1 - 0.0017 17.1 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_30 PF13604.6 ORY99133.1 - 0.0082 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY99133.1 - 0.013 15.9 0.2 0.047 14.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 ORY99133.1 - 0.023 14.6 0.2 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain Cwf_Cwc_15 PF04889.12 ORY99133.1 - 1.5 8.5 7.5 2.7 7.7 7.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RED_C PF07807.11 ORY99135.1 - 8e-20 71.4 7.3 8e-20 71.4 7.3 3.5 4 0 0 4 4 4 1 RED-like protein C-terminal region RED_N PF07808.13 ORY99135.1 - 1.8e-17 63.7 11.7 7.1e-17 61.8 0.8 3.4 4 0 0 4 4 4 2 RED-like protein N-terminal region Pkinase PF00069.25 ORY99136.1 - 1.1e-53 182.4 0.0 1.3e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99136.1 - 2.7e-21 76.0 0.1 1.8e-20 73.4 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY99136.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY99136.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 ORY99136.1 - 0.073 12.6 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 ORY99136.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Zn_clus PF00172.18 ORY99140.1 - 4.7e-08 33.0 13.3 4.7e-08 33.0 13.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Snapin_Pallidin PF14712.6 ORY99141.1 - 0.037 14.4 13.7 1.8 9.0 0.0 3.5 2 1 1 3 3 3 0 Snapin/Pallidin ABC_tran_CTD PF16326.5 ORY99141.1 - 0.057 13.7 0.0 0.057 13.7 0.0 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF16 PF01519.16 ORY99141.1 - 0.076 13.5 13.7 0.88 10.1 0.0 3.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 DASH_Duo1 PF08651.10 ORY99141.1 - 0.099 12.4 5.1 3.4 7.5 0.9 3.4 3 0 0 3 3 3 0 DASH complex subunit Duo1 Nsp1_C PF05064.13 ORY99141.1 - 0.11 12.3 9.1 0.93 9.3 2.1 2.8 2 1 1 3 3 3 0 Nsp1-like C-terminal region Vps51 PF08700.11 ORY99141.1 - 0.42 10.7 5.9 12 6.1 0.0 3.6 3 0 0 3 3 3 0 Vps51/Vps67 FlaC_arch PF05377.11 ORY99141.1 - 0.5 10.8 10.1 6.7 7.2 0.1 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF4298 PF14131.6 ORY99141.1 - 0.69 9.9 13.0 2.4 8.2 3.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) Synaptonemal_3 PF15191.6 ORY99141.1 - 5.5 6.8 7.4 4.5 7.1 0.5 3.1 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 Vac_Fusion PF02346.16 ORY99141.1 - 5.8 6.6 8.8 8.9 6.0 0.7 4.0 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 YlqD PF11068.8 ORY99141.1 - 8.1 6.8 20.7 11 6.4 0.3 2.7 2 1 0 2 2 2 0 YlqD protein zf-rbx1 PF12678.7 ORY99143.1 - 4.1e-12 46.2 4.3 1.2e-11 44.7 4.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY99143.1 - 1.9e-07 31.3 11.0 1.9e-07 31.3 11.0 2.8 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY99143.1 - 1.8e-06 27.8 1.4 7.1e-06 26.0 1.4 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY99143.1 - 1.9e-06 27.6 4.8 8e-06 25.6 4.8 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY99143.1 - 6.2e-06 26.0 3.0 6.2e-06 26.0 3.0 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY99143.1 - 5.5e-05 23.2 1.5 0.0002 21.4 1.5 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 ORY99143.1 - 0.00032 20.2 2.5 0.001 18.6 2.5 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 ORY99143.1 - 0.00034 20.6 6.1 0.0015 18.5 6.1 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY99143.1 - 0.0011 18.7 4.1 0.0012 18.6 1.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY99143.1 - 0.0017 18.3 6.8 0.011 15.6 7.0 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY99143.1 - 0.0023 17.8 2.1 0.0023 17.8 2.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY99143.1 - 0.018 14.8 1.7 0.018 14.8 1.7 2.7 2 0 0 2 2 2 0 RING-like zinc finger FANCL_C PF11793.8 ORY99143.1 - 0.024 14.8 0.8 0.024 14.8 0.8 2.8 3 0 0 3 3 3 0 FANCL C-terminal domain Cid2 PF09774.9 ORY99143.1 - 0.041 14.3 4.3 0.12 12.8 4.3 1.8 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF3974 PF13120.6 ORY99143.1 - 0.082 13.0 0.2 0.25 11.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) zf-RING-like PF08746.11 ORY99143.1 - 0.19 12.1 4.5 0.53 10.6 4.5 1.8 1 0 0 1 1 1 0 RING-like domain CTU2 PF10288.9 ORY99143.1 - 4.7 7.5 9.7 2.1 8.6 4.1 2.7 2 1 0 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Ank_2 PF12796.7 ORY99144.1 - 3.7e-11 43.5 1.4 1.2e-05 25.8 0.5 3.1 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY99144.1 - 6.8e-10 39.3 1.4 0.0011 19.4 0.1 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY99144.1 - 2.9e-09 37.0 4.5 0.00053 20.2 0.3 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY99144.1 - 3.6e-09 36.7 6.4 0.00031 21.0 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ORY99144.1 - 2.3e-08 33.6 2.5 0.045 14.3 0.0 4.9 5 0 0 5 5 4 2 Ankyrin repeat KilA-N PF04383.13 ORY99144.1 - 0.00065 19.5 2.8 0.0023 17.8 0.3 2.6 2 1 0 2 2 1 1 KilA-N domain GAS PF13851.6 ORY99144.1 - 0.0038 16.6 9.0 0.0054 16.1 5.4 2.3 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Cast PF10174.9 ORY99144.1 - 0.012 13.9 6.1 0.02 13.1 6.1 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone KASH_CCD PF14662.6 ORY99144.1 - 0.012 15.5 12.0 0.053 13.3 7.0 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 ORY99144.1 - 0.031 14.7 1.3 0.17 12.3 1.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 ORY99144.1 - 0.037 12.9 15.2 0.03 13.2 9.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein PDDEXK_1 PF12705.7 ORY99144.1 - 0.046 13.6 1.5 0.083 12.8 1.5 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily V_ATPase_I PF01496.19 ORY99144.1 - 0.11 10.4 0.9 0.17 9.8 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4795 PF16043.5 ORY99144.1 - 0.11 12.0 4.9 2.4 7.7 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) YabA PF06156.13 ORY99144.1 - 0.45 11.2 6.4 23 5.7 3.3 2.7 2 0 0 2 2 2 0 Initiation control protein YabA MCC-bdg_PDZ PF10506.9 ORY99144.1 - 0.81 9.7 6.8 1.1 9.3 0.9 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Leu_zip PF15294.6 ORY99144.1 - 0.97 8.9 8.2 0.1 12.1 3.6 1.6 2 0 0 2 2 1 0 Leucine zipper COG2 PF06148.11 ORY99144.1 - 1.6 8.8 6.9 0.2 11.8 2.5 1.8 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TEX13 PF15186.6 ORY99144.1 - 1.7 8.3 9.0 3.1 7.5 0.4 2.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family OmpH PF03938.14 ORY99144.1 - 1.7 9.0 18.4 0.31 11.4 7.9 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 ORY99144.1 - 2.6 8.6 13.5 3.3 8.2 6.3 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Sec34 PF04136.15 ORY99144.1 - 4.3 7.2 6.7 2 8.3 4.0 1.8 2 0 0 2 2 1 0 Sec34-like family Golgin_A5 PF09787.9 ORY99144.1 - 6.8 6.1 15.4 2.5 7.5 11.7 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF2415 PF10313.9 ORY99145.1 - 2.3e-13 49.9 0.8 2.1e-11 43.6 0.1 3.3 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 ORY99145.1 - 6.4e-08 32.8 0.0 0.47 10.8 0.0 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY99145.1 - 4.5e-05 24.1 1.1 0.12 13.3 0.3 4.7 6 0 0 6 6 6 1 WD domain, G-beta repeat Prot_ATP_OB_N PF17758.1 ORY99145.1 - 0.024 14.3 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain SEEK1 PF15357.6 ORY99145.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Psoriasis susceptibility 1 candidate 1 RabGAP-TBC PF00566.18 ORY99146.1 - 1.5e-39 135.9 2.9 1.5e-39 135.9 2.9 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 ORY99146.1 - 3.8e-14 52.5 0.2 1.1e-12 47.8 0.1 2.2 1 1 1 2 2 2 1 Rab-binding domain (RBD) DUF1542 PF07564.11 ORY99146.1 - 0.1 12.7 4.8 0.29 11.3 4.8 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) LUC7 PF03194.15 ORY99147.1 - 5e-71 239.3 16.8 6.7e-71 238.9 16.8 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DUF4175 PF13779.6 ORY99147.1 - 0.00083 17.4 10.4 0.0012 16.9 10.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Phage_GPO PF05929.11 ORY99147.1 - 0.0064 16.1 4.3 0.0091 15.6 4.3 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase FUSC PF04632.12 ORY99147.1 - 0.047 12.2 3.0 0.062 11.8 3.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIF4G_like_2 PF09090.11 ORY99147.1 - 0.098 12.1 5.8 0.13 11.7 5.8 1.2 1 0 0 1 1 1 0 MIF4G like Ran-binding PF05508.11 ORY99147.1 - 0.12 11.3 6.0 0.12 11.3 1.7 2.1 2 0 0 2 2 2 0 RanGTP-binding protein DUF4407 PF14362.6 ORY99147.1 - 0.23 10.8 8.3 0.32 10.3 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CP12 PF02672.15 ORY99147.1 - 0.29 11.9 8.1 0.08 13.7 2.7 2.6 3 0 0 3 3 2 0 CP12 domain LPP PF04728.13 ORY99147.1 - 0.45 10.9 3.6 5.1 7.6 0.4 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Exonuc_VII_L PF02601.15 ORY99147.1 - 0.56 9.7 6.8 0.75 9.3 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Swi5 PF07061.11 ORY99147.1 - 0.82 9.8 8.6 1.6 8.9 2.5 2.5 2 0 0 2 2 2 0 Swi5 DASH_Spc34 PF08657.10 ORY99147.1 - 1.6 8.5 13.9 2.2 8.0 10.5 2.2 1 1 1 2 2 2 0 DASH complex subunit Spc34 MRP-L46 PF11788.8 ORY99147.1 - 3 8.6 11.0 4.1 8.2 9.0 2.4 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Spc24 PF08286.11 ORY99147.1 - 4.4 7.6 8.6 0.77 10.0 0.8 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4363 PF14276.6 ORY99147.1 - 5.4 7.2 8.8 4.1 7.6 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) FmiP_Thoc5 PF09766.9 ORY99147.1 - 7.7 5.7 16.1 29 3.8 16.1 2.0 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 V_ATPase_I PF01496.19 ORY99147.1 - 8.2 4.2 9.2 11 3.7 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADK PF00406.22 ORY99148.1 - 2.8e-47 160.6 0.1 3.7e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY99148.1 - 3.9e-39 134.2 0.6 6.1e-39 133.6 0.2 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY99148.1 - 4.5e-11 43.4 0.4 7.8e-11 42.6 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY99148.1 - 9e-07 29.1 0.0 1.4e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 ORY99148.1 - 1e-06 28.6 0.7 0.04 13.6 0.1 2.4 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 ORY99148.1 - 0.0018 17.6 0.0 0.0042 16.4 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin dNK PF01712.19 ORY99148.1 - 0.079 12.8 0.1 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_28 PF13521.6 ORY99148.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NMO PF03060.15 ORY99149.1 - 3.3e-56 191.1 2.1 4.2e-55 187.4 2.1 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY99149.1 - 1.3e-12 47.4 0.1 1.4e-10 40.8 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Peripla_BP_6 PF13458.6 ORY99149.1 - 0.018 14.8 0.7 0.13 11.9 0.1 2.3 2 1 1 3 3 3 0 Periplasmic binding protein DUF1902 PF08972.11 ORY99149.1 - 0.13 12.3 0.2 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) FMN_dh PF01070.18 ORY99149.1 - 0.15 11.0 2.4 0.26 10.2 2.4 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Pex24p PF06398.11 ORY99150.1 - 6e-23 81.4 11.9 1.1e-22 80.6 11.9 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Big_4 PF07532.11 ORY99150.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) GPS2_interact PF15784.5 ORY99151.1 - 0.002 18.5 0.3 0.0049 17.3 0.3 1.6 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain FlxA PF14282.6 ORY99151.1 - 0.013 15.5 2.2 0.32 11.0 0.2 2.3 2 0 0 2 2 2 0 FlxA-like protein Mitofilin PF09731.9 ORY99151.1 - 0.015 14.1 1.3 0.021 13.7 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF5304 PF17230.2 ORY99151.1 - 0.059 13.6 0.1 0.084 13.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5304) SlyX PF04102.12 ORY99151.1 - 0.076 13.6 4.8 0.55 10.9 1.6 2.5 1 1 1 2 2 2 0 SlyX Miff PF05644.11 ORY99151.1 - 0.081 12.5 4.9 0.22 11.1 4.9 1.7 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Siah-Interact_N PF09032.11 ORY99151.1 - 0.12 12.7 3.7 0.22 11.9 0.3 2.6 2 1 0 2 2 2 0 Siah interacting protein, N terminal Lzipper-MIP1 PF14389.6 ORY99151.1 - 0.14 12.5 2.3 1.6 9.1 0.6 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 RAP1 PF07218.11 ORY99151.1 - 0.17 10.1 1.1 0.2 9.9 1.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM76 PF16046.5 ORY99151.1 - 1.1 8.6 3.8 1.5 8.1 3.8 1.1 1 0 0 1 1 1 0 FAM76 protein Abhydrolase_3 PF07859.13 ORY99152.1 - 1.5e-48 165.5 0.0 1.8e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY99152.1 - 3.9e-06 26.0 0.0 1.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY99152.1 - 5.6e-05 22.2 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.7 ORY99152.1 - 0.00037 19.5 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ORY99152.1 - 0.0053 16.2 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family NAD_kinase PF01513.21 ORY99152.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase AXE1 PF05448.12 ORY99152.1 - 0.14 10.8 0.0 0.29 9.8 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) IF4E PF01652.18 ORY99154.1 - 4.5e-57 192.3 0.1 5.3e-57 192.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E F-box PF00646.33 ORY99155.1 - 1.8e-06 27.6 5.1 3.6e-06 26.7 0.1 3.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORY99155.1 - 2.5e-06 27.3 2.5 6e-06 26.1 0.1 2.9 3 0 0 3 3 3 1 F-box-like Glyco_transf_22 PF03901.17 ORY99156.1 - 1.7e-66 225.2 13.2 2e-66 225.0 13.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HD PF01966.22 ORY99157.1 - 2.4e-13 50.4 0.7 7.6e-13 48.8 0.1 2.1 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 ORY99157.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase eIF-1a PF01176.19 ORY99158.1 - 3.6e-15 55.5 0.0 4.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TFIIS_M PF07500.14 ORY99159.1 - 5e-22 78.5 0.0 6.1e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Herpes_UL14 PF03580.14 ORY99160.1 - 0.022 15.0 0.4 0.033 14.5 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Pex24p PF06398.11 ORY99160.1 - 0.03 13.3 0.3 0.034 13.1 0.3 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Bclx_interact PF08945.10 ORY99161.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Spc7_N PF15402.6 ORY99161.1 - 0.097 10.9 2.6 0.12 10.6 2.6 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Dicty_REP PF05086.12 ORY99161.1 - 0.16 9.9 1.8 0.2 9.6 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Oxysterol_BP PF01237.18 ORY99162.1 - 1.1e-67 228.6 4.8 1.1e-67 228.6 4.8 3.1 2 1 0 2 2 2 1 Oxysterol-binding protein zf-C2H2_jaz PF12171.8 ORY99162.1 - 0.011 16.0 0.0 0.038 14.3 0.0 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Sun2_CC2 PF18580.1 ORY99162.1 - 0.066 13.4 0.4 0.18 12.1 0.4 1.7 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 RRM_1 PF00076.22 ORY99163.1 - 1.4e-26 92.0 0.0 4e-12 45.8 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY99163.1 - 1.1e-06 28.5 0.3 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY99163.1 - 0.004 17.2 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 ORY99163.1 - 0.071 12.9 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain CPSF100_C PF13299.6 ORY99163.1 - 1.4 9.1 16.4 0.082 13.1 7.9 2.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal EMC3_TMCO1 PF01956.16 ORY99163.1 - 2.7 7.7 5.4 4.5 7.0 5.4 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RR_TM4-6 PF06459.12 ORY99163.1 - 3 7.6 21.7 0.87 9.4 15.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 ORY99163.1 - 4 6.8 14.1 0.25 10.7 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 ORY99163.1 - 6.1 7.1 26.8 2 8.7 19.3 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Cytadhesin_P30 PF07271.11 ORY99163.1 - 7.2 6.1 9.5 1.6 8.3 6.3 1.5 2 0 0 2 2 2 0 Cytadhesin P30/P32 Zip PF02535.22 ORY99163.1 - 7.3 5.7 7.8 0.26 10.4 1.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter KASH_CCD PF14662.6 ORY99164.1 - 0.0061 16.4 2.1 0.011 15.6 2.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH MscS_porin PF12795.7 ORY99164.1 - 0.013 15.1 5.0 0.013 15.1 5.0 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Fez1 PF06818.15 ORY99164.1 - 0.02 15.3 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Fez1 RPA_C PF08784.11 ORY99164.1 - 0.052 14.2 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 Replication protein A C terminal Lebercilin PF15619.6 ORY99164.1 - 0.067 12.8 4.5 0.14 11.8 4.5 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.22 ORY99164.1 - 0.092 13.0 1.3 0.24 11.6 1.3 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Bombinin PF05298.11 ORY99164.1 - 0.14 11.8 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 Bombinin Mod_r PF07200.13 ORY99164.1 - 0.18 11.9 4.6 11 6.1 3.8 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PKcGMP_CC PF16808.5 ORY99164.1 - 0.22 11.4 3.8 2.7 7.9 0.2 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 ORY99164.1 - 0.41 9.5 4.7 1.6 7.6 4.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 ORY99164.1 - 1.4 8.2 6.7 0.76 9.1 3.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 ORY99165.1 - 0.0065 16.5 1.6 0.014 15.4 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Rootletin PF15035.6 ORY99165.1 - 0.029 14.4 2.3 0.059 13.4 2.3 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 ORY99165.1 - 0.13 12.7 2.4 0.15 12.4 0.7 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF484 PF04340.12 ORY99165.1 - 0.45 10.2 5.7 0.86 9.3 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 YabA PF06156.13 ORY99165.1 - 0.46 11.2 2.6 0.43 11.2 0.8 2.0 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 ORY99165.1 - 0.46 10.3 5.3 1.1 9.1 5.3 1.6 1 0 0 1 1 1 0 Septum formation initiator HTH_ABP1_N PF18107.1 ORY99167.1 - 8.2e-06 25.5 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 ORY99167.1 - 0.00023 21.1 0.0 0.007 16.4 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 ORY99167.1 - 0.027 15.1 0.0 0.11 13.1 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DNA_pol_A_exo1 PF01612.20 ORY99169.1 - 3.6e-12 46.4 0.0 1.8e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease CAF1 PF04857.20 ORY99169.1 - 0.04 13.1 0.7 1.3 8.1 0.0 2.5 3 0 0 3 3 3 0 CAF1 family ribonuclease DUF1942 PF09167.11 ORY99169.1 - 0.11 12.4 0.0 5.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1942) Pkinase PF00069.25 ORY99170.1 - 2.1e-64 217.4 0.0 4.6e-64 216.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99170.1 - 1.6e-46 158.7 0.0 2.7e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY99170.1 - 4.3e-07 29.1 0.0 4.3e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 ORY99170.1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY99170.1 - 0.092 12.7 0.3 0.31 10.9 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S4e PF00900.20 ORY99171.1 - 1.8e-38 130.3 0.8 3.3e-38 129.4 0.8 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY99171.1 - 2.1e-25 88.1 0.1 4.1e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY99171.1 - 4.6e-19 68.2 8.0 1.5e-18 66.6 8.1 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 ORY99171.1 - 7.3e-07 28.8 0.1 4.1e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORY99171.1 - 0.006 16.5 5.0 0.016 15.1 2.2 3.0 3 1 0 3 3 3 1 KOW motif Sipho_tail PF05709.11 ORY99171.1 - 0.024 14.1 0.3 0.052 13.0 0.3 1.4 1 1 0 1 1 1 0 Phage tail protein Zn_clus PF00172.18 ORY99172.1 - 6.2e-11 42.2 10.5 1.2e-10 41.3 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.12 ORY99172.1 - 0.15 10.8 3.4 0.19 10.4 3.4 1.1 1 0 0 1 1 1 0 Per os infectivity Met_10 PF02475.16 ORY99173.1 - 3.6e-68 229.2 0.0 4.9e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ORY99173.1 - 0.0004 19.7 0.0 0.00053 19.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 ORY99173.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MethyltransfD12 PF02086.15 ORY99173.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.15 ORY99173.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltrans_SAM PF10672.9 ORY99173.1 - 0.041 13.0 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_23 PF13489.6 ORY99173.1 - 0.042 13.7 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_9 PF16293.5 ORY99173.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) CUE PF02845.16 ORY99174.1 - 1.5e-09 37.3 0.1 0.001 18.8 0.0 2.6 2 0 0 2 2 2 2 CUE domain DUF1771 PF08590.10 ORY99174.1 - 1e-07 32.2 5.6 1e-07 32.2 5.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 ORY99174.1 - 8.5e-07 29.3 0.0 2.3e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Smr domain DUF5532 PF17673.1 ORY99174.1 - 0.0059 16.6 1.1 0.19 11.8 0.0 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5532) DMA PF03474.14 ORY99174.1 - 0.039 13.6 0.2 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif DUF1743 PF08489.11 ORY99174.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) POX PF07526.11 ORY99174.1 - 5.3 7.6 6.6 0.51 10.9 0.2 2.5 2 1 0 2 2 2 0 Associated with HOX Frataxin_Cyay PF01491.16 ORY99176.1 - 1.7e-41 140.7 0.0 1.9e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain HSF_DNA-bind PF00447.17 ORY99180.1 - 2e-28 98.8 7.4 4.3e-28 97.8 7.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding N6_N4_Mtase PF01555.18 ORY99180.1 - 0.055 13.2 0.3 0.067 12.9 0.3 1.2 1 0 0 1 1 1 0 DNA methylase H-kinase_dim PF02895.14 ORY99180.1 - 0.55 10.7 4.2 5.3 7.5 4.2 2.4 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain EssA PF10661.9 ORY99181.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA VPS28 PF03997.12 ORY99182.1 - 1.2e-69 233.8 0.8 1.3e-69 233.7 0.8 1.0 1 0 0 1 1 1 1 VPS28 protein LTXXQ PF07813.12 ORY99182.1 - 0.023 15.4 1.0 0.061 14.1 1.0 1.7 1 1 0 1 1 1 0 LTXXQ motif family protein Mg_trans_NIPA PF05653.14 ORY99183.1 - 2.5e-105 351.8 19.2 3.1e-105 351.5 19.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY99183.1 - 1.1e-07 32.2 3.5 1.1e-07 32.2 3.5 3.7 3 1 0 3 3 3 2 EamA-like transporter family DUF2937 PF11157.8 ORY99183.1 - 0.21 11.3 0.7 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Synaptobrevin PF00957.21 ORY99184.1 - 1.9e-32 110.9 0.8 2.3e-32 110.6 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 ORY99184.1 - 0.016 15.3 0.1 0.018 15.2 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter GIT1_C PF12205.8 ORY99184.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF5345 PF17280.2 ORY99184.1 - 0.039 13.9 0.3 0.091 12.7 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Fzo_mitofusin PF04799.13 ORY99184.1 - 1.7 8.1 6.4 0.34 10.5 0.3 2.0 1 1 1 2 2 2 0 fzo-like conserved region VWA PF00092.28 ORY99187.1 - 8.3e-05 22.9 0.4 0.00029 21.1 0.4 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 ORY99188.1 - 8.4e-131 430.7 0.5 1.3e-26 93.2 0.0 8.5 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 ORY99188.1 - 1.2e-59 199.0 7.1 1.2e-22 80.1 0.0 5.4 6 0 0 6 6 4 4 Midasin AAA lid domain AAA_3 PF07726.11 ORY99188.1 - 2.1e-34 118.2 0.0 1.3e-07 31.5 0.0 7.2 8 0 0 8 8 6 6 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 ORY99188.1 - 1.3e-33 115.2 0.5 1.2e-32 112.1 0.0 2.9 2 0 0 2 2 2 1 Midasin AAA lid domain AAA PF00004.29 ORY99188.1 - 1.3e-30 106.5 0.0 1.2e-05 25.7 0.0 7.1 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY99188.1 - 2.3e-30 105.4 2.8 3.2e-06 26.8 0.0 7.0 7 0 0 7 7 6 5 P-loop containing dynein motor region AAA_6 PF12774.7 ORY99188.1 - 4.8e-25 88.2 2.2 0.00071 18.6 0.1 8.4 8 0 0 8 8 8 6 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 ORY99188.1 - 1.7e-24 87.1 18.2 0.00036 21.0 0.3 8.9 7 3 0 7 7 6 6 AAA ATPase domain AAA_18 PF13238.6 ORY99188.1 - 3.2e-24 85.9 1.4 0.014 15.9 0.0 7.0 6 0 0 6 6 6 6 AAA domain AAA_22 PF13401.6 ORY99188.1 - 2.9e-23 82.7 5.7 0.00031 21.0 0.0 8.3 8 0 0 8 8 6 4 AAA domain Sigma54_activat PF00158.26 ORY99188.1 - 8.5e-23 80.9 0.0 0.00089 19.0 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain Dynein_heavy PF03028.15 ORY99188.1 - 9.2e-23 80.6 0.1 0.0009 19.3 0.0 7.6 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain ABC_tran PF00005.27 ORY99188.1 - 7.8e-19 68.6 0.9 0.0049 17.4 0.0 7.6 7 0 0 7 7 7 3 ABC transporter Sigma54_activ_2 PF14532.6 ORY99188.1 - 2.2e-18 66.7 0.3 0.00016 21.8 0.0 6.5 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_14 PF13173.6 ORY99188.1 - 8.1e-18 64.7 0.0 0.0019 18.2 0.0 7.5 7 0 0 7 7 7 3 AAA domain TsaE PF02367.17 ORY99188.1 - 4.8e-17 62.1 4.6 0.078 13.0 0.0 6.5 6 0 0 6 6 6 5 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ORY99188.1 - 8.9e-17 61.4 0.0 0.015 15.1 0.0 8.1 8 0 0 8 8 8 3 AAA domain AAA_33 PF13671.6 ORY99188.1 - 4.5e-15 56.0 1.7 0.28 11.3 0.0 7.1 6 0 0 6 6 6 2 AAA domain Zeta_toxin PF06414.12 ORY99188.1 - 1.3e-14 54.0 0.4 0.42 9.9 0.0 6.7 6 0 0 6 6 6 4 Zeta toxin RsgA_GTPase PF03193.16 ORY99188.1 - 1.9e-13 50.7 1.9 0.34 10.8 0.0 6.5 6 0 0 6 6 6 2 RsgA GTPase AAA_28 PF13521.6 ORY99188.1 - 6.4e-13 49.3 11.9 0.16 12.2 0.0 7.2 7 0 0 7 7 6 2 AAA domain AAA_29 PF13555.6 ORY99188.1 - 5.9e-12 45.2 0.4 2.9 7.7 0.0 6.7 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY99188.1 - 8.4e-12 45.1 6.9 0.62 9.6 0.0 6.2 6 1 0 6 6 5 4 AAA domain RNA_helicase PF00910.22 ORY99188.1 - 2.1e-11 44.2 2.3 0.46 10.9 0.0 6.5 6 0 0 6 6 6 2 RNA helicase Rad17 PF03215.15 ORY99188.1 - 1.1e-10 41.8 1.3 0.18 11.7 0.0 5.8 6 0 0 6 6 5 2 Rad17 P-loop domain AAA_23 PF13476.6 ORY99188.1 - 2.7e-10 41.1 0.0 5.4 7.5 0.0 6.4 6 0 0 6 6 6 0 AAA domain T2SSE PF00437.20 ORY99188.1 - 3.2e-10 39.5 3.4 1.1 8.2 0.0 6.2 6 0 0 6 6 6 1 Type II/IV secretion system protein NACHT PF05729.12 ORY99188.1 - 4.2e-10 39.8 9.6 0.11 12.4 0.0 6.3 7 0 0 7 7 5 3 NACHT domain RuvB_N PF05496.12 ORY99188.1 - 1.3e-09 38.0 1.2 0.42 10.4 0.0 7.4 8 0 0 8 8 7 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 ORY99188.1 - 1.4e-09 37.5 0.5 0.54 9.4 0.0 5.8 6 0 0 6 6 6 3 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 ORY99188.1 - 1.4e-09 37.6 1.4 10 5.4 0.0 8.4 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 ORY99188.1 - 9.7e-09 35.1 4.5 0.032 14.0 0.0 5.8 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_2 PF07724.14 ORY99188.1 - 2.6e-08 34.2 0.2 4.1 7.5 0.0 6.7 6 1 0 6 6 6 0 AAA domain (Cdc48 subfamily) Roc PF08477.13 ORY99188.1 - 1.2e-07 31.9 1.3 4 7.7 0.0 6.2 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORY99188.1 - 2.4e-07 30.5 5.6 1.9 8.0 0.0 6.3 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 ORY99188.1 - 3.1e-07 30.3 1.2 0.32 10.7 0.0 5.6 6 0 0 6 6 6 1 AAA domain AAA_9 PF12781.7 ORY99188.1 - 7.2e-07 28.6 0.0 1.9 7.5 0.0 5.3 5 1 0 5 5 5 1 ATP-binding dynein motor region TniB PF05621.11 ORY99188.1 - 7.4e-07 28.8 0.1 3.3 7.1 0.0 6.0 6 0 0 6 6 5 0 Bacterial TniB protein CPT PF07931.12 ORY99188.1 - 2.6e-06 27.4 3.7 3.7 7.4 0.0 7.8 9 1 0 9 9 6 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.17 ORY99188.1 - 4.4e-06 26.5 0.5 2.6 7.8 0.0 5.8 6 0 0 6 6 6 0 IstB-like ATP binding protein ResIII PF04851.15 ORY99188.1 - 8.8e-06 25.8 0.8 1.7 8.7 0.0 4.9 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 ORY99188.1 - 8.8e-06 25.6 0.1 1.9 8.1 0.0 5.5 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase SRPRB PF09439.10 ORY99188.1 - 1.7e-05 24.4 1.1 9.3 5.6 0.0 6.1 7 0 0 7 7 6 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY99188.1 - 1.7e-05 24.8 3.6 7.6 6.7 0.0 5.8 6 0 0 6 6 5 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 ORY99188.1 - 2.7e-05 24.1 7.9 2.2 8.1 0.1 5.9 6 0 0 6 6 5 1 NTPase AAA_19 PF13245.6 ORY99188.1 - 3.2e-05 24.3 13.3 0.25 11.7 0.0 6.7 8 1 0 8 8 5 1 AAA domain SRP54 PF00448.22 ORY99188.1 - 3.3e-05 23.6 12.2 0.098 12.3 0.1 5.7 7 0 0 7 7 5 2 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 ORY99188.1 - 3.7e-05 23.8 0.1 17 5.2 0.0 6.1 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea dNK PF01712.19 ORY99188.1 - 7.6e-05 22.6 7.5 6.4 6.6 0.0 6.3 6 0 0 6 6 6 0 Deoxynucleoside kinase AAA_11 PF13086.6 ORY99188.1 - 9.8e-05 22.3 1.7 12 5.5 0.0 5.5 6 0 0 6 6 5 0 AAA domain Thymidylate_kin PF02223.17 ORY99188.1 - 0.00014 21.6 6.5 4 7.1 0.0 6.1 7 0 0 7 7 6 0 Thymidylate kinase DEAD PF00270.29 ORY99188.1 - 0.00048 19.9 0.5 22 4.8 0.0 4.9 5 0 0 5 5 4 0 DEAD/DEAH box helicase TIP49 PF06068.13 ORY99188.1 - 0.00056 19.2 0.9 3.5 6.8 0.1 5.2 6 0 0 6 6 6 0 TIP49 P-loop domain ATP_bind_1 PF03029.17 ORY99188.1 - 0.00061 19.6 8.2 1.7 8.3 0.1 5.6 6 0 0 6 6 5 1 Conserved hypothetical ATP binding protein AAA_8 PF12780.7 ORY99188.1 - 0.001 18.5 3.6 17 4.6 0.0 5.6 6 0 0 6 6 5 0 P-loop containing dynein motor region D4 AAA_21 PF13304.6 ORY99188.1 - 0.0011 18.9 0.8 0.49 10.2 0.1 4.3 5 0 0 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Cytidylate_kin PF02224.18 ORY99188.1 - 0.0014 18.4 0.1 24 4.6 0.0 4.6 5 0 0 5 5 4 0 Cytidylate kinase MCM PF00493.23 ORY99188.1 - 0.002 17.3 0.0 15 4.6 0.0 4.2 4 0 0 4 4 4 0 MCM P-loop domain IPT PF01745.16 ORY99188.1 - 0.0021 17.5 2.0 4.7 6.5 0.0 5.1 5 0 0 5 5 5 0 Isopentenyl transferase AAA_17 PF13207.6 ORY99188.1 - 0.0023 18.3 4.2 0.17 12.3 0.1 4.6 4 0 0 4 4 4 1 AAA domain ATPase PF06745.13 ORY99188.1 - 0.0026 17.1 0.3 11 5.2 0.0 4.1 4 0 0 4 4 4 0 KaiC AAA_15 PF13175.6 ORY99188.1 - 0.0044 16.8 0.0 20 4.8 0.0 3.6 3 0 0 3 3 3 0 AAA ATPase domain Importin_rep_5 PF18816.1 ORY99188.1 - 0.0089 16.3 0.1 0.041 14.2 0.1 2.2 1 0 0 1 1 1 1 Importin repeat tRNA_lig_kinase PF08303.11 ORY99188.1 - 0.015 15.4 0.4 0.29 11.2 0.1 3.0 2 0 0 2 2 2 0 tRNA ligase kinase domain KAP_NTPase PF07693.14 ORY99188.1 - 0.016 14.5 0.0 40 3.3 0.0 4.7 5 0 0 5 5 5 0 KAP family P-loop domain G-alpha PF00503.20 ORY99188.1 - 0.017 14.3 0.1 10 5.2 0.0 3.6 3 0 0 3 3 3 0 G-protein alpha subunit TrwB_AAD_bind PF10412.9 ORY99188.1 - 0.017 14.1 3.4 5.1 5.9 0.0 4.2 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain PRK PF00485.18 ORY99188.1 - 0.021 14.6 2.1 30 4.3 0.0 4.2 5 0 0 5 5 3 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 ORY99188.1 - 0.027 14.1 0.1 21 4.7 0.0 3.6 3 1 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Bac_DnaA PF00308.18 ORY99188.1 - 0.034 14.0 0.2 38 4.0 0.0 4.0 5 0 0 5 5 3 0 Bacterial dnaA protein DUF853 PF05872.12 ORY99188.1 - 0.045 12.4 3.0 0.45 9.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 ORY99188.1 - 0.054 12.9 1.1 10 5.4 0.0 3.8 4 0 0 4 4 3 0 FtsK/SpoIIIE family DUF87 PF01935.17 ORY99188.1 - 0.13 12.4 1.8 10 6.1 0.0 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain MobB PF03205.14 ORY99188.1 - 0.14 12.1 6.9 18 5.3 0.1 5.4 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.22 ORY99188.1 - 0.14 12.3 3.8 2.6 8.1 0.0 4.0 5 0 0 5 5 3 0 Shikimate kinase Septin PF00735.18 ORY99188.1 - 0.2 10.9 2.4 16 4.7 0.0 4.0 5 0 0 5 5 4 0 Septin FeoB_N PF02421.18 ORY99188.1 - 0.25 10.8 2.6 37 3.8 0.0 3.9 5 0 0 5 5 3 0 Ferrous iron transport protein B CbiA PF01656.23 ORY99188.1 - 4.9 7.2 7.3 14 5.8 0.0 4.3 6 0 0 6 6 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain GRIP PF01465.20 ORY99189.1 - 2.2e-16 59.4 1.0 9e-16 57.5 1.0 2.2 1 0 0 1 1 1 1 GRIP domain LMP PF04778.12 ORY99189.1 - 0.001 19.0 28.6 0.001 19.0 28.6 8.0 2 2 5 8 8 8 2 LMP repeated region Fez1 PF06818.15 ORY99189.1 - 0.003 18.0 32.1 0.003 18.0 32.1 7.1 1 1 7 8 8 8 2 Fez1 FlaC_arch PF05377.11 ORY99189.1 - 0.021 15.2 4.7 0.021 15.2 4.7 18.1 7 4 10 18 18 18 0 Flagella accessory protein C (FlaC) DUF21 PF01595.20 ORY99190.1 - 1.1e-36 126.2 0.8 2.2e-36 125.2 0.8 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORY99190.1 - 1.2e-06 28.8 0.1 0.032 14.7 0.1 2.7 3 0 0 3 3 3 2 CBS domain Ints3 PF10189.9 ORY99191.1 - 2.4e-66 223.2 0.1 4.5e-66 222.4 0.1 1.5 1 0 0 1 1 1 1 Integrator complex subunit 3 DUF383 PF04063.14 ORY99192.1 - 6.7e-54 182.5 0.0 1.1e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF383) RTP1_C1 PF10363.9 ORY99192.1 - 0.015 15.5 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 PP-binding PF00550.25 ORY99193.1 - 2.1e-13 50.4 0.3 2.8e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORY99193.1 - 1.5e-05 25.1 0.5 1.8e-05 24.9 0.5 1.3 1 0 0 1 1 1 1 Acyl-carrier PAC1 PF16094.5 ORY99195.1 - 2.2e-10 40.2 3.3 2.4e-10 40.1 0.2 2.0 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 Cofilin_ADF PF00241.20 ORY99196.1 - 3.4e-30 104.3 0.1 4.6e-14 52.2 0.1 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein SUR7 PF06687.12 ORY99197.1 - 7.9e-15 55.1 13.4 1.4e-14 54.2 13.4 1.4 1 1 0 1 1 1 1 SUR7/PalI family Oxidored_q3 PF00499.20 ORY99197.1 - 0.0029 17.4 3.0 0.0046 16.7 0.0 2.3 2 1 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PMP22_Claudin PF00822.20 ORY99197.1 - 8.9 6.2 10.6 2.3e+02 1.6 9.9 2.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family RNase_H2_suC PF08615.11 ORY99199.1 - 2.8e-10 40.5 2.7 3.5e-05 24.0 0.3 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ribosomal_S15 PF00312.22 ORY99200.1 - 1.5e-30 105.2 3.4 3.7e-30 103.9 3.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3463 PF11946.8 ORY99200.1 - 0.15 11.8 0.2 3.6 7.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3463) AA_permease_2 PF13520.6 ORY99201.1 - 1.2e-27 96.9 22.7 1.5e-27 96.5 22.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY99201.1 - 5e-16 58.3 15.3 6.5e-16 58.0 15.3 1.1 1 0 0 1 1 1 1 Amino acid permease CrgA PF06781.12 ORY99201.1 - 4.7 7.3 6.1 10 6.2 0.0 3.3 3 0 0 3 3 3 0 Cell division protein CrgA S36_mt PF10937.8 ORY99202.1 - 5.1 8.7 9.3 2.8 9.6 1.5 2.3 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial PIP5K PF01504.18 ORY99203.1 - 1.1e-99 333.1 2.1 1.3e-99 332.9 2.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CBM_14 PF01607.24 ORY99205.1 - 9.8e-12 44.9 0.4 9.8e-12 44.9 0.4 1.3 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain RasGEF PF00617.19 ORY99206.1 - 2.9e-57 193.7 0.1 2.9e-57 193.7 0.1 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 ORY99206.1 - 3e-24 85.3 1.4 3e-24 85.3 1.4 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 ORY99206.1 - 3.8e-12 45.6 0.1 7.4e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY99206.1 - 1.6e-10 40.7 0.1 9.2e-10 38.2 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORY99206.1 - 1.6e-09 37.3 0.0 7.3e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 ORY99206.1 - 2.3e-07 30.8 6.8 9.7e-07 28.8 2.0 2.7 2 0 0 2 2 2 1 WW domain DUF1178 PF06676.11 ORY99206.1 - 5.2 7.4 8.6 4.3 7.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Spt20 PF12090.8 ORY99206.1 - 5.7 6.5 17.8 17 4.9 17.8 1.8 1 0 0 1 1 1 0 Spt20 family RRM_1 PF00076.22 ORY99207.1 - 1.8e-27 94.9 0.2 3.1e-09 36.5 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY99207.1 - 2.4e-12 46.5 0.0 0.0019 18.0 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY99207.1 - 1.9e-05 24.6 0.5 0.12 12.5 0.1 2.7 3 0 0 3 3 3 2 RNA binding motif DUF4523 PF15023.6 ORY99207.1 - 5.1e-05 23.2 0.0 0.4 10.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 ORY99207.1 - 0.00046 20.3 0.0 1.4 9.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 ORY99207.1 - 0.081 12.5 0.0 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_6 PF13516.6 ORY99209.1 - 6.7e-18 63.2 23.7 0.0024 17.8 0.0 10.4 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 ORY99209.1 - 5.9e-07 29.7 27.3 0.52 10.8 1.7 6.9 3 3 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY99209.1 - 1e-06 28.4 22.2 0.085 12.6 1.3 7.5 6 3 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 ORY99209.1 - 4.4e-06 26.5 23.1 16 6.5 0.0 8.3 7 2 0 7 7 7 3 Leucine Rich Repeat LRR_2 PF07723.13 ORY99209.1 - 2.3 9.0 4.9 35 5.3 1.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat CDC27 PF09507.10 ORY99211.1 - 0.057 12.8 29.3 0.066 12.6 29.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Penaeidin PF05927.11 ORY99211.1 - 0.089 13.5 0.1 0.23 12.2 0.1 1.6 1 0 0 1 1 1 0 Penaeidin TFIIA PF03153.13 ORY99211.1 - 6.9 6.6 26.5 7.9 6.4 26.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-binding PF00249.31 ORY99212.1 - 1.5e-71 236.3 35.9 3.6e-10 39.9 0.2 9.2 9 0 0 9 9 9 9 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY99212.1 - 5.3e-64 212.4 24.0 3.8e-13 49.5 0.2 9.1 6 2 3 9 9 9 9 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY99212.1 - 1.4e-08 34.5 4.9 0.4 10.6 0.0 6.3 5 2 1 6 6 6 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 ORY99212.1 - 2.6e-05 24.5 0.7 2.6e-05 24.5 0.7 8.0 7 4 0 7 7 7 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 ORY99212.1 - 0.012 15.7 0.9 15 5.9 0.0 3.8 3 1 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 ORY99212.1 - 0.04 14.0 6.6 21 5.3 1.4 5.5 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY99212.1 - 5.8 7.2 20.9 2.4 8.4 1.7 5.2 5 1 1 6 6 6 0 SANT/Myb-like domain of DAMP1 IIGP PF05049.13 ORY99213.1 - 1.9e-18 66.7 0.0 2.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 ORY99213.1 - 1e-07 32.0 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ORY99213.1 - 0.0031 17.7 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 ORY99213.1 - 0.0037 17.8 0.0 0.006 17.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 ORY99213.1 - 0.0042 16.6 0.0 0.016 14.8 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORY99213.1 - 0.005 16.4 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY99213.1 - 0.0066 16.5 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 ORY99213.1 - 0.011 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY99213.1 - 0.013 15.4 0.2 0.038 13.9 0.1 1.7 1 1 1 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 ORY99213.1 - 0.019 15.2 0.1 0.043 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY99213.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY99213.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 ORY99213.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 ORY99213.1 - 0.21 10.9 0.0 0.45 9.7 0.0 1.5 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 ORY99213.1 - 0.23 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 AIG1 family DUF2347 PF09804.9 ORY99215.1 - 4.1e-33 115.2 0.7 1.1e-32 113.8 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 ORY99215.1 - 6.6e-11 42.2 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DUF4484 PF14831.6 ORY99215.1 - 3.3e-07 30.6 4.6 4.5e-06 26.9 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.9 ORY99215.1 - 0.0012 17.6 0.0 0.18 10.5 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 Pkinase PF00069.25 ORY99216.1 - 6.4e-66 222.4 0.0 7.7e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99216.1 - 1.7e-18 66.9 0.0 7.3e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY99216.1 - 6.8e-06 26.2 0.3 4.2e-05 23.6 0.4 2.2 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY99216.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY99216.1 - 0.027 13.8 0.2 0.078 12.3 0.0 1.8 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 ORY99216.1 - 0.029 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 ORY99216.1 - 0.045 13.3 0.1 0.088 12.4 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex14_N PF04695.13 ORY99217.1 - 1.6e-28 100.4 3.5 1.6e-28 100.4 3.5 3.1 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PBECR5 PF18814.1 ORY99217.1 - 6.8 6.5 8.8 3.7 7.4 6.0 1.7 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Profilin PF00235.19 ORY99218.1 - 1.4e-51 174.0 0.2 1.6e-51 173.9 0.2 1.0 1 0 0 1 1 1 1 Profilin DNA_repr_REX1B PF14966.6 ORY99219.1 - 4.7e-26 91.3 1.5 5e-26 91.2 0.6 1.5 2 0 0 2 2 2 1 DNA repair REX1-B Baculo_PEP_C PF04513.12 ORY99219.1 - 0.0002 21.4 0.4 0.026 14.6 0.0 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 ORY99219.1 - 0.00095 19.3 0.2 0.011 15.8 0.1 2.0 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 THOC7 PF05615.13 ORY99219.1 - 0.0015 18.8 0.5 0.0065 16.7 0.1 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 COG5 PF10392.9 ORY99219.1 - 0.0066 16.6 0.1 1.4 9.1 0.0 2.1 1 1 1 2 2 2 1 Golgi transport complex subunit 5 GAS PF13851.6 ORY99219.1 - 0.0079 15.6 0.3 0.067 12.5 0.1 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 ORY99219.1 - 0.01 16.1 0.4 1.4 9.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) APG6_N PF17675.1 ORY99219.1 - 0.029 14.9 0.9 0.058 13.9 0.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region FUSC PF04632.12 ORY99219.1 - 0.05 12.2 0.6 0.056 12.0 0.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 ORY99219.1 - 0.057 13.6 0.4 0.094 12.9 0.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF2358 PF10184.9 ORY99219.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) NleF_casp_inhib PF16809.5 ORY99219.1 - 0.15 12.0 1.4 4.8 7.1 0.0 2.2 1 1 1 2 2 2 0 NleF caspase inhibitor Syntaxin-6_N PF09177.11 ORY99219.1 - 0.38 11.3 2.5 1.6 9.4 2.5 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal zf-Tim10_DDP PF02953.15 ORY99220.1 - 5.1e-24 83.7 1.9 6.5e-24 83.4 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Erf4 PF10256.9 ORY99220.1 - 0.065 13.3 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family 4HBT PF03061.22 ORY99221.1 - 1.6e-11 44.4 0.0 4.2e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 ORY99221.1 - 0.0043 17.2 0.0 0.0058 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 ORY99221.1 - 0.038 14.2 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily NAD_binding_1 PF00175.21 ORY99222.1 - 5.9e-30 104.1 0.0 1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY99222.1 - 6.3e-23 81.0 0.0 1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY99222.1 - 2.3e-08 34.3 0.1 9.7e-06 25.8 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Velvet PF11754.8 ORY99223.1 - 1.6e-42 146.2 2.0 3.7e-28 99.1 0.3 3.4 2 2 1 3 3 3 2 Velvet factor Chorion_2 PF03964.15 ORY99223.1 - 0.66 10.8 15.4 1.7 9.5 8.1 2.4 2 0 0 2 2 2 0 Chorion family 2 SRF-TF PF00319.18 ORY99224.1 - 3.3e-21 74.5 0.1 5.1e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CBF PF03914.17 ORY99224.1 - 0.074 13.1 0.7 0.14 12.2 0.7 1.6 1 1 0 1 1 1 0 CBF/Mak21 family MFS_1 PF07690.16 ORY99225.1 - 3.8e-21 75.4 43.4 5.5e-13 48.6 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY99225.1 - 1.9e-05 23.7 7.3 1.9e-05 23.7 7.3 4.0 2 2 1 3 3 3 2 Sugar (and other) transporter DUF3450 PF11932.8 ORY99226.1 - 0.22 10.8 5.3 0.27 10.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TIP41 PF04176.13 ORY99227.1 - 3.7e-66 221.9 0.4 4.6e-66 221.5 0.4 1.1 1 0 0 1 1 1 1 TIP41-like family DUF4743 PF15916.5 ORY99228.1 - 9.9e-20 70.7 0.0 1.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 ORY99228.1 - 8.6e-05 22.6 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MaoC_dehydratas PF01575.19 ORY99229.1 - 3e-31 107.5 0.0 5.8e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY99229.1 - 1.7e-06 28.2 0.0 8.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase UCH PF00443.29 ORY99230.1 - 5.4e-38 131.0 0.0 8.9e-38 130.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY99230.1 - 4.4e-09 36.4 5.6 9.5e-08 32.0 5.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Copper-fist PF00649.18 ORY99231.1 - 3.5e-21 74.4 2.0 8.5e-21 73.2 2.0 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain Lipoprotein_18 PF06804.11 ORY99232.1 - 0.23 10.5 12.7 1.1 8.2 0.4 2.2 2 0 0 2 2 2 0 NlpB/DapX lipoprotein CDK5_activator PF03261.15 ORY99232.1 - 1.8 8.0 18.7 2.8 7.4 6.3 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein EF-hand_1 PF00036.32 ORY99233.1 - 2.6e-35 117.3 16.6 5.7e-09 34.9 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY99233.1 - 4.7e-28 97.5 8.8 5.8e-14 52.3 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY99233.1 - 5.3e-27 91.4 11.8 1.7e-08 33.7 0.4 5.0 4 2 2 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 ORY99233.1 - 7.5e-23 79.0 16.2 4.9e-06 25.8 0.9 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY99233.1 - 3.7e-22 77.9 12.7 1.2e-10 41.1 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 ORY99233.1 - 2.3e-14 53.5 0.2 2.9e-06 27.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORY99233.1 - 8.3e-08 32.1 2.2 0.0022 17.9 0.3 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY99233.1 - 3.3e-05 24.2 0.4 0.057 13.8 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 ORY99233.1 - 0.0049 17.7 0.1 0.45 11.4 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 ORY99233.1 - 0.0081 14.8 0.0 0.0082 14.7 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) PMBR PF09373.10 ORY99233.1 - 0.011 15.9 0.2 6.3 7.1 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat Glyco_hydro_56 PF01630.18 ORY99233.1 - 0.023 13.7 0.0 0.062 12.3 0.0 1.6 1 1 1 2 2 2 0 Hyaluronidase Caleosin PF05042.13 ORY99233.1 - 0.08 12.9 1.2 11 5.9 0.1 3.1 1 1 2 3 3 3 0 Caleosin related protein Dockerin_1 PF00404.18 ORY99233.1 - 0.083 13.1 6.3 2.8 8.2 0.0 3.4 2 1 2 4 4 4 0 Dockerin type I domain L27 PF02828.16 ORY99233.1 - 0.14 12.0 0.0 2.7 7.8 0.0 2.6 2 1 0 2 2 2 0 L27 domain Pribosyltran PF00156.27 ORY99234.1 - 0.005 16.4 0.0 0.0078 15.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SRA1 PF07304.11 ORY99235.1 - 2.2e-13 50.3 11.0 5.8e-13 48.9 11.0 1.8 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 ORY99235.1 - 1.1e-06 28.8 0.3 2.2e-05 24.5 0.2 2.0 1 1 1 2 2 2 1 Prp18 domain Mito_carr PF00153.27 ORY99236.1 - 1.5e-67 223.6 2.2 4.9e-23 80.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NuiA PF07924.11 ORY99237.1 - 4.8e-10 39.9 0.0 6.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Nuclease A inhibitor-like protein STI1 PF17830.1 ORY99237.1 - 0.41 10.6 2.6 0.76 9.8 2.6 1.4 1 0 0 1 1 1 0 STI1 domain CUE PF02845.16 ORY99238.1 - 5.7e-07 29.1 0.0 1.7e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 CUE domain DUF1318 PF07027.12 ORY99238.1 - 0.11 12.9 1.2 0.39 11.2 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) PknG_rubred PF16919.5 ORY99238.1 - 4.5 7.4 5.8 0.66 10.1 0.2 2.4 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain FGGY_C PF02782.16 ORY99239.1 - 4.6e-45 153.8 0.0 7.8e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY99239.1 - 3.7e-24 85.6 0.0 1.3e-23 83.9 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 ORY99239.1 - 1.7e-05 24.5 0.0 0.0095 15.5 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family RunxI PF08504.11 ORY99240.1 - 7.9e-06 26.5 10.1 0.013 16.2 0.2 4.7 1 1 4 5 5 5 2 Runx inhibition domain DNA_pol3_beta_2 PF02767.16 ORY99240.1 - 0.0086 16.3 14.7 8.1 6.7 0.1 6.2 3 1 4 7 7 7 1 DNA polymerase III beta subunit, central domain TBCA PF02970.16 ORY99240.1 - 0.83 10.0 38.2 8.8 6.7 1.3 7.3 1 1 6 7 7 7 0 Tubulin binding cofactor A ARGLU PF15346.6 ORY99240.1 - 2.9 7.7 17.9 9 6.2 2.4 3.4 1 1 2 3 3 3 0 Arginine and glutamate-rich 1 DUF883 PF05957.13 ORY99240.1 - 5.3 7.7 17.1 3 8.5 2.3 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 ORY99240.1 - 6.5 6.9 18.4 1.9 8.6 2.4 4.2 1 1 3 4 4 4 0 ATP synthase B/B' CF(0) OHA PF14418.6 ORY99240.1 - 9 6.2 10.0 35 4.3 0.1 4.8 5 1 1 6 6 6 0 OST-HTH Associated domain DNA_pol3_beta_2 PF02767.16 ORY99241.1 - 0.28 11.4 2.7 16 5.8 0.1 3.1 3 0 0 3 3 3 0 DNA polymerase III beta subunit, central domain DUF2992 PF11208.8 ORY99241.1 - 0.32 11.2 29.1 0.94 9.7 8.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2992) RunxI PF08504.11 ORY99241.1 - 0.86 10.3 4.9 9.4 7.0 0.2 3.0 1 1 2 3 3 3 0 Runx inhibition domain HlyE PF06109.13 ORY99241.1 - 2.8 7.2 12.9 6.5 6.0 0.4 3.0 2 1 1 3 3 3 0 Haemolysin E (HlyE) TBCA PF02970.16 ORY99241.1 - 3.1 8.2 18.9 4.8 7.6 2.6 3.3 2 1 1 3 3 3 0 Tubulin binding cofactor A zf-C2H2_jaz PF12171.8 ORY99243.1 - 5.3e-05 23.4 0.5 0.0001 22.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY99243.1 - 0.0012 19.5 1.2 0.032 15.1 1.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY99243.1 - 0.027 14.8 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ORY99243.1 - 0.038 14.4 3.3 0.059 13.9 1.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 ORY99243.1 - 0.062 13.7 0.7 0.12 12.8 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY99243.1 - 0.099 13.1 0.3 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.12 ORY99243.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ATG16 PF08614.11 ORY99244.1 - 0.0061 16.8 11.1 0.0061 16.8 11.1 3.2 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) KDZ PF18758.1 ORY99245.1 - 6.5e-57 192.7 0.1 1.4e-56 191.6 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 ORY99245.1 - 2.8e-10 40.3 0.2 6e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 ORY99245.1 - 6.1e-07 29.6 1.1 1.1e-06 28.7 0.3 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CENP-B_dimeris PF09026.10 ORY99245.1 - 7.8 7.0 17.0 30 5.1 17.0 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ECSCR PF15820.5 ORY99250.1 - 0.6 10.0 5.2 1.1 9.2 5.2 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Fungal_trans PF04082.18 ORY99251.1 - 6.5e-17 61.4 0.0 9.9e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain LOH1CR12 PF10158.9 ORY99253.1 - 0.091 12.8 0.9 0.78 9.8 0.1 2.2 1 1 1 2 2 2 0 Tumour suppressor protein Pkinase PF00069.25 ORY99255.1 - 8.6e-66 222.0 0.0 1e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99255.1 - 1.1e-22 80.6 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY99255.1 - 3.4e-05 23.3 0.0 0.00063 19.1 0.0 2.4 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 ORY99255.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY99255.1 - 0.012 15.5 0.0 0.033 14.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1679 PF07914.11 ORY99255.1 - 0.025 13.4 0.4 0.046 12.6 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) FTA2 PF13095.6 ORY99255.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORY99255.1 - 0.1 11.4 0.3 8.3 5.1 0.1 2.0 1 1 1 2 2 2 0 Fungal protein kinase Actin PF00022.19 ORY99256.1 - 3.7e-152 506.6 0.0 1.4e-151 504.7 0.0 1.7 1 1 0 1 1 1 1 Actin ATG13 PF10033.9 ORY99257.1 - 1.9e-40 139.1 0.0 4.2e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 13 WRNPLPNID PF15017.6 ORY99257.1 - 1.1 10.2 7.4 0.15 12.9 0.6 2.8 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box FYDLN_acid PF09538.10 ORY99257.1 - 5.4 7.8 10.9 2.3 8.9 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 ORY99257.1 - 5.9 6.5 13.1 1.9 8.2 5.9 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein V-SNARE_C PF12352.8 ORY99258.1 - 3.3e-05 24.1 2.7 0.11 12.8 0.3 3.0 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.11 ORY99258.1 - 0.57 10.5 6.6 1.3 9.3 0.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MCC-bdg_PDZ PF10506.9 ORY99258.1 - 1.3 9.1 5.4 8.9 6.4 0.1 3.4 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome NPV_P10 PF05531.12 ORY99258.1 - 1.3 9.5 8.3 1.3 9.6 0.4 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nucleoporin_FG PF13634.6 ORY99258.1 - 5.8 7.8 7.3 2.3 9.1 2.2 2.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region GAS PF13851.6 ORY99259.1 - 0.00089 18.7 1.7 0.00089 18.7 1.7 3.8 4 0 0 4 4 4 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ORY99259.1 - 0.071 12.0 23.9 0.07 12.0 0.9 3.7 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF16 PF01519.16 ORY99259.1 - 0.15 12.6 13.3 1.4 9.4 0.5 4.1 4 0 0 4 4 4 0 Protein of unknown function DUF16 DUF4971 PF16341.5 ORY99259.1 - 0.3 10.9 0.5 0.58 10.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Takusan PF04822.13 ORY99259.1 - 6 6.8 15.9 0.62 10.0 0.2 4.4 5 0 0 5 5 5 0 Takusan Phage_Mu_Gam PF07352.12 ORY99259.1 - 8.3 6.3 14.9 0.12 12.3 2.3 2.9 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Mg_trans_NIPA PF05653.14 ORY99260.1 - 2.7e-61 207.3 12.5 9.3e-59 198.9 11.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORY99260.1 - 4.2e-06 27.0 1.1 4.2e-06 27.0 1.1 3.9 3 1 0 3 3 3 1 EamA-like transporter family GPR_Gpa2_C PF11970.8 ORY99260.1 - 0.062 13.4 1.1 0.15 12.1 1.1 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term CobU PF02283.16 ORY99260.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4256 PF14066.6 ORY99260.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) HlyIII PF03006.20 ORY99260.1 - 6.4 6.4 14.3 3.8 7.2 4.9 2.8 1 1 1 2 2 2 0 Haemolysin-III related TssN PF17555.2 ORY99260.1 - 9.7 5.5 9.8 25 4.1 9.7 1.7 1 1 1 2 2 2 0 Type VI secretion system, TssN WD40 PF00400.32 ORY99261.1 - 3.1e-15 56.3 0.1 1e-05 26.2 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY99261.1 - 2.4e-06 27.7 0.0 0.11 12.8 0.0 3.9 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain S10_plectin PF03501.15 ORY99262.1 - 2.1e-43 146.3 0.1 2.5e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 ORY99262.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB XPA_C PF05181.12 ORY99263.1 - 5e-24 84.0 1.1 1e-23 83.0 1.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus eIF-3c_N PF05470.12 ORY99263.1 - 0.00088 17.7 0.0 0.0014 17.0 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus XPA_N PF01286.18 ORY99263.1 - 0.0021 18.1 3.6 0.0021 18.1 3.6 2.3 2 0 0 2 2 2 1 XPA protein N-terminal zf-C3HC4_3 PF13920.6 ORY99263.1 - 0.016 15.0 2.0 0.02 14.7 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) W2 PF02020.18 ORY99263.1 - 0.061 13.5 1.5 0.061 13.5 1.5 2.1 2 1 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon CpXC PF14353.6 ORY99263.1 - 3.5 7.7 7.2 0.47 10.5 0.4 2.9 3 1 0 3 3 3 0 CpXC protein RF-1 PF00472.20 ORY99263.1 - 3.8 7.5 12.4 0.47 10.4 4.1 2.3 2 0 0 2 2 2 0 RF-1 domain zf_UBZ PF18439.1 ORY99263.1 - 5.6 6.7 9.7 3.5 7.3 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger GTP_EFTU PF00009.27 ORY99264.1 - 3.8e-58 196.2 0.8 5.4e-58 195.7 0.8 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY99264.1 - 6.9e-31 106.9 1.3 7.6e-31 106.7 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY99264.1 - 1.2e-17 64.1 2.5 2.7e-17 62.9 2.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY99264.1 - 1.4e-05 25.1 0.1 2.9e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 ORY99264.1 - 0.0006 19.4 0.2 0.0023 17.6 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 ORY99264.1 - 0.0025 17.7 0.2 0.011 15.6 0.1 2.0 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 ORY99264.1 - 0.017 14.9 0.3 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AMP-binding PF00501.28 ORY99268.1 - 2.7e-72 243.7 0.0 3.3e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY99268.1 - 1.4e-13 51.6 0.0 2.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MMS22L_C PF14911.6 ORY99268.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Aa_trans PF01490.18 ORY99269.1 - 1.8e-61 208.1 21.9 2.6e-61 207.6 21.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF962 PF06127.11 ORY99269.1 - 0.031 14.4 0.3 0.47 10.6 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Hist_deacetyl PF00850.19 ORY99270.1 - 1.1e-83 281.3 0.0 1.4e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DNA_pol_A_exo1 PF01612.20 ORY99271.1 - 2e-16 60.2 0.0 4.6e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease Myc_N PF01056.18 ORY99271.1 - 0.016 15.1 4.0 0.028 14.3 4.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region SGT1 PF07093.11 ORY99271.1 - 0.017 13.6 5.4 0.073 11.5 6.2 1.6 2 0 0 2 2 2 0 SGT1 protein Dynamin_N PF00350.23 ORY99271.1 - 0.025 14.7 1.3 0.059 13.4 1.3 1.6 1 0 0 1 1 1 0 Dynamin family Cwf_Cwc_15 PF04889.12 ORY99271.1 - 0.052 13.3 13.8 0.098 12.4 13.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spt4 PF06093.13 ORY99271.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger SAPS PF04499.15 ORY99271.1 - 0.28 9.9 4.6 0.43 9.3 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 ORY99271.1 - 0.69 9.3 17.9 1.1 8.6 17.9 1.2 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 ORY99271.1 - 1 9.6 18.8 2.9 8.1 18.8 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 ORY99271.1 - 1.1 7.4 20.1 1.6 6.9 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 ORY99271.1 - 1.7 7.9 13.3 3 7.1 13.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 ORY99271.1 - 2 8.4 11.8 4.7 7.2 11.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.10 ORY99271.1 - 2.1 7.6 18.6 0.015 14.7 9.7 1.7 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 ORY99271.1 - 2.7 6.2 18.3 4.3 5.5 18.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 ORY99271.1 - 3.3 6.5 10.8 5.4 5.9 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Dicty_REP PF05086.12 ORY99271.1 - 3.3 5.6 12.0 4.8 5.0 12.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop25 PF09805.9 ORY99271.1 - 3.8 8.0 15.2 8.4 6.9 15.2 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) ATG16 PF08614.11 ORY99272.1 - 0.0026 18.0 14.0 0.0026 18.0 14.0 3.4 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) CTNNBL PF08216.11 ORY99272.1 - 0.016 15.4 3.4 0.1 12.7 1.0 2.7 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear HAP1_N PF04849.13 ORY99272.1 - 0.036 13.3 0.3 0.036 13.3 0.3 3.5 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF2935 PF11155.8 ORY99272.1 - 0.041 14.2 4.5 1.1 9.6 1.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Synaptonemal_3 PF15191.6 ORY99272.1 - 0.064 13.0 1.7 0.15 11.9 1.3 1.9 1 1 0 1 1 1 0 Synaptonemal complex central element protein 3 MscS_porin PF12795.7 ORY99272.1 - 0.1 12.2 31.0 0.8 9.2 9.5 3.6 2 1 0 3 3 3 0 Mechanosensitive ion channel porin domain ABC_tran_CTD PF16326.5 ORY99272.1 - 0.14 12.5 22.0 0.61 10.4 2.2 3.9 4 0 0 4 4 4 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 ORY99272.1 - 0.5 10.4 32.2 0.11 12.5 10.8 3.8 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 ORY99272.1 - 0.7 8.3 10.6 1.2 7.6 10.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bap31_Bap29_C PF18035.1 ORY99272.1 - 0.86 9.7 5.6 0.21 11.6 0.7 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain TSC22 PF01166.18 ORY99272.1 - 1.2 9.5 11.2 4.3 7.7 0.3 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family Spc7 PF08317.11 ORY99272.1 - 1.8 7.4 30.0 0.027 13.4 14.3 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Pex14_N PF04695.13 ORY99272.1 - 4.1 8.0 16.0 0.19 12.4 1.4 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DASH_Hsk3 PF08227.11 ORY99272.1 - 4.7 7.6 11.2 2.9 8.3 0.6 4.2 3 1 0 3 3 3 0 DASH complex subunit Hsk3 like DUF948 PF06103.11 ORY99272.1 - 4.9 7.5 10.4 1.1 9.5 0.8 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Uso1_p115_C PF04871.13 ORY99272.1 - 5.7 7.3 28.3 0.067 13.6 7.6 3.7 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region SlyX PF04102.12 ORY99272.1 - 6 7.6 18.8 13 6.5 0.9 4.7 2 1 2 4 4 4 0 SlyX TMF_TATA_bd PF12325.8 ORY99272.1 - 9 6.6 38.3 0.18 12.1 4.5 4.4 3 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding LRR_8 PF13855.6 ORY99273.1 - 2.8e-50 167.9 52.1 2e-14 53.0 2.7 6.7 2 2 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 ORY99273.1 - 1.1e-28 98.8 35.4 4e-07 30.2 0.1 8.0 3 3 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY99273.1 - 3.3e-10 39.2 18.5 0.038 14.0 0.1 9.2 9 0 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.6 ORY99273.1 - 4.3e-10 39.4 13.1 4.2e-05 23.1 1.1 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 ORY99273.1 - 1.6e-08 33.9 32.5 0.077 13.6 0.0 10.7 10 2 0 10 10 10 4 Leucine Rich Repeat Glyco_transf_15 PF01793.16 ORY99274.1 - 1.7e-88 297.0 10.0 2.1e-88 296.7 10.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase KinB_sensor PF16767.5 ORY99274.1 - 0.051 14.0 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Laps PF10169.9 ORY99275.1 - 0.063 13.9 0.1 0.21 12.2 0.1 1.7 2 0 0 2 2 2 0 Learning-associated protein RCDG1 PF15725.5 ORY99275.1 - 1.7 9.2 15.0 0.39 11.2 7.3 2.6 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein LtrA PF06772.11 ORY99276.1 - 9.7e-40 136.9 25.2 9.7e-40 136.9 25.2 2.0 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Period_C PF12114.8 ORY99276.1 - 0.62 9.6 4.7 1.1 8.8 4.7 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region F-box-like PF12937.7 ORY99277.1 - 1.3e-06 28.2 0.3 3e-06 27.0 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY99277.1 - 0.00036 20.3 0.1 0.00093 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain Ldh_1_C PF02866.18 ORY99278.1 - 3.9e-48 163.5 0.0 6.9e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORY99278.1 - 1e-46 158.5 0.2 2.4e-46 157.3 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ORY99278.1 - 2.5e-05 23.4 0.0 6.7e-05 22.0 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY99278.1 - 0.0015 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 ORY99278.1 - 0.0083 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 ORY99278.1 - 0.013 14.9 0.4 0.53 9.6 0.1 2.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CAF1 PF04857.20 ORY99279.1 - 1.6e-20 73.6 1.4 5.7e-10 38.9 0.0 2.9 3 1 0 3 3 3 2 CAF1 family ribonuclease GATA PF00320.27 ORY99281.1 - 5.3e-13 48.3 4.3 1.1e-12 47.3 4.3 1.5 1 0 0 1 1 1 1 GATA zinc finger FGF-BP1 PF06473.12 ORY99281.1 - 0.3 10.9 8.9 0.8 9.5 8.9 1.6 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Mito_carr PF00153.27 ORY99282.1 - 1.7e-68 226.6 3.2 3.4e-24 84.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 ORY99282.1 - 0.0018 17.5 0.1 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 Fuseless Aminotran_3 PF00202.21 ORY99283.1 - 1.7e-118 395.8 0.0 2e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III OAM_dimer PF16554.5 ORY99283.1 - 0.13 12.7 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase WD40 PF00400.32 ORY99284.1 - 1.1e-41 140.0 11.6 2.3e-07 31.4 0.4 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.12 ORY99284.1 - 4.4e-36 124.8 8.9 4.4e-36 124.8 8.9 3.1 2 1 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 ORY99284.1 - 2.3e-14 53.4 0.1 0.00034 20.9 0.0 5.6 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY99284.1 - 3e-06 26.2 0.2 0.067 11.9 0.1 3.9 2 1 2 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 ORY99284.1 - 0.0023 16.7 0.8 17 3.9 0.0 4.4 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY99284.1 - 0.0073 15.3 0.1 7.3 5.4 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY99284.1 - 0.01 15.7 0.0 0.076 12.9 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF5046 PF16465.5 ORY99284.1 - 0.079 12.4 0.2 2.7 7.4 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) B12D PF06522.11 ORY99285.1 - 2.1e-22 78.7 0.1 2.7e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PIRT PF15099.6 ORY99285.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family NPBW PF15180.6 ORY99285.1 - 0.059 13.2 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Neuropeptides B and W PH PF00169.29 ORY99287.1 - 4.2e-15 56.1 3.8 3.4e-05 24.3 0.5 3.8 3 0 0 3 3 3 3 PH domain PH_4 PF15404.6 ORY99287.1 - 7.1e-12 45.5 6.1 5.3e-08 32.9 2.3 4.2 2 2 1 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 ORY99287.1 - 4.4e-07 30.3 2.5 0.0039 17.5 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 ORY99287.1 - 6 7.3 7.9 13 6.3 0.4 4.0 3 2 0 3 3 3 0 Pleckstrin homology domain Lyase_1 PF00206.20 ORY99292.1 - 5.8e-23 81.8 0.0 8.6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORY99292.1 - 4e-17 62.5 0.0 1.2e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 ORY99292.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Aa_trans PF01490.18 ORY99294.1 - 5.7e-14 51.6 27.3 1e-13 50.8 27.3 1.5 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY99294.1 - 4.1e-06 26.1 14.9 4.1e-06 26.1 14.9 2.2 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family FeS_assembly_P PF01883.19 ORY99295.1 - 6.3e-13 48.7 0.3 1.1e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein FolB PF02152.18 ORY99295.1 - 0.039 14.5 0.4 0.35 11.4 0.1 2.1 1 1 1 2 2 2 0 Dihydroneopterin aldolase GSHPx PF00255.19 ORY99296.1 - 9.8e-42 140.9 0.4 1.2e-41 140.6 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY99296.1 - 3.6e-08 33.4 0.3 2.2e-07 30.8 0.3 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY99296.1 - 4.3e-06 26.5 0.1 6.5e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 Redoxin AHJR-like PF18743.1 ORY99296.1 - 0.091 12.3 0.1 0.41 10.2 0.0 2.0 1 1 1 2 2 2 0 REase_AHJR-like Lipase_3 PF01764.25 ORY99297.1 - 1.6e-13 50.8 0.0 4.4e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 ORY99297.1 - 0.00096 19.4 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain CDI PF02234.19 ORY99297.1 - 0.15 12.2 0.1 0.47 10.7 0.1 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor YqzE PF14038.6 ORY99297.1 - 0.17 11.9 0.0 16 5.6 0.0 2.8 2 0 0 2 2 2 0 YqzE-like protein Actin PF00022.19 ORY99299.1 - 4.2e-115 384.6 0.0 2e-114 382.4 0.0 1.7 1 1 0 1 1 1 1 Actin SLS PF14611.6 ORY99302.1 - 1.4e-11 44.7 0.1 2.3e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 ORY99302.1 - 0.004 17.0 0.4 0.018 14.9 0.2 2.1 2 0 0 2 2 2 1 KH domain DUF2039 PF10217.9 ORY99303.1 - 2.2e-31 108.1 14.7 3.6e-31 107.4 14.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Dicty_REP PF05086.12 ORY99303.1 - 0.68 7.8 11.1 1 7.3 11.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cript PF10235.9 ORY99303.1 - 1.3 9.6 17.1 8.8 7.0 17.1 2.2 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 ORY99303.1 - 2 8.5 12.5 6.7 6.8 12.5 1.8 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.19 ORY99303.1 - 2 8.4 9.1 87 3.2 9.1 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AATase PF07247.12 ORY99304.1 - 2e-07 30.0 0.0 2.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Vps4_C PF09336.10 ORY99304.1 - 0.09 12.8 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Transferase PF02458.15 ORY99304.1 - 0.096 11.3 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Transferase family p450 PF00067.22 ORY99305.1 - 4.4e-58 197.1 0.0 6.1e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AD PF09793.9 ORY99306.1 - 1.5e-28 98.8 3.9 3.6e-28 97.5 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain Gemin6 PF06372.12 ORY99306.1 - 0.0039 16.7 0.0 0.072 12.6 0.0 2.2 2 0 0 2 2 2 1 Gemin6 protein Med15 PF09606.10 ORY99306.1 - 0.01 14.5 6.2 0.011 14.4 6.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FliJ PF02050.16 ORY99306.1 - 0.023 14.9 11.7 0.023 14.9 11.7 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein DUF702 PF05142.12 ORY99306.1 - 0.041 14.4 5.4 0.069 13.6 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) MMU163 PF17119.5 ORY99306.1 - 0.094 11.9 3.3 0.16 11.1 3.3 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis LSM PF01423.22 ORY99306.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 LSM domain Presenilin PF01080.17 ORY99306.1 - 0.24 10.1 3.2 0.22 10.3 3.2 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 ORY99306.1 - 0.25 11.4 11.6 2.2 8.4 0.0 2.1 1 1 0 2 2 2 0 DDHD domain Spt20 PF12090.8 ORY99306.1 - 0.38 10.3 14.7 0.54 9.8 14.7 1.2 1 0 0 1 1 1 0 Spt20 family Hydin_ADK PF17213.3 ORY99306.1 - 2.4 8.4 8.7 3.9 7.7 8.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4834 PF16118.5 ORY99306.1 - 6.5 7.8 8.9 13 6.8 8.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-C2HC5 PF06221.13 ORY99307.1 - 2e-22 78.9 7.7 3.4e-22 78.2 7.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TPD PF14811.6 ORY99307.1 - 1.1 9.1 4.4 0.45 10.4 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif zf-C2H2_4 PF13894.6 ORY99312.1 - 1.1 10.3 4.0 0.39 11.7 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY99313.1 - 0.00081 19.6 3.0 0.067 13.5 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY99313.1 - 0.0017 19.0 6.2 0.83 10.7 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY99313.1 - 0.0053 17.1 3.5 2 9.1 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 ORY99313.1 - 0.12 13.0 2.8 3.9 8.2 0.1 2.9 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 ORY99313.1 - 0.98 7.9 2.8 9.4 4.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 ORY99313.1 - 3.2 8.2 5.7 5.9 7.3 1.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 ORY99313.1 - 6.9 6.4 6.4 18 5.0 0.9 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF1977 PF09320.11 ORY99320.1 - 1.6e-07 31.6 5.5 5.4 7.3 0.0 5.8 1 1 5 6 6 6 5 Domain of unknown function (DUF1977) MAGUK_N_PEST PF10608.9 ORY99320.1 - 1.2e-05 25.7 6.6 17 5.9 0.1 5.8 1 1 5 6 6 6 1 Polyubiquitination (PEST) N-terminal domain of MAGUK Gal-3-0_sulfotr PF06990.11 ORY99320.1 - 0.019 13.9 0.0 1.1 8.1 0.0 2.2 1 1 0 2 2 2 0 Galactose-3-O-sulfotransferase TRI9 PF08195.11 ORY99320.1 - 0.051 13.5 15.3 8.4 6.4 0.2 5.1 1 1 5 6 6 6 0 TRI9 protein DUF268 PF03269.14 ORY99320.1 - 0.064 13.1 0.0 71 3.2 0.0 3.5 2 1 2 4 4 4 0 Caenorhabditis protein of unknown function, DUF268 Brr6_like_C_C PF10104.9 ORY99320.1 - 1.8 8.4 4.8 32 4.3 0.1 3.8 1 1 3 4 4 4 0 Di-sulfide bridge nucleocytoplasmic transport domain zf-RING_4 PF14570.6 ORY99321.1 - 2e-22 78.7 11.4 4.3e-22 77.7 11.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY99321.1 - 1.4e-06 28.0 9.1 1.4e-06 28.0 9.1 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 ORY99321.1 - 5.4e-05 22.9 0.1 0.00056 19.7 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 ORY99321.1 - 0.00051 19.8 8.8 0.011 15.6 4.8 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY99321.1 - 0.0019 18.5 11.8 0.0047 17.2 11.8 1.7 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 ORY99321.1 - 0.0023 17.9 3.9 0.0048 16.9 3.9 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 ORY99321.1 - 0.043 13.7 10.9 0.099 12.5 10.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 ORY99321.1 - 0.054 13.6 3.9 0.15 12.2 3.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Rrn6 PF10214.9 ORY99321.1 - 0.082 11.4 11.9 0.025 13.1 7.9 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor zf-C3HC4 PF00097.25 ORY99321.1 - 0.086 12.7 11.3 0.2 11.5 11.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.6 ORY99321.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-RING_UBOX PF13445.6 ORY99321.1 - 0.24 11.5 6.3 0.77 9.8 5.4 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Rtf2 PF04641.12 ORY99321.1 - 0.41 10.0 14.4 0.066 12.6 1.8 2.5 3 0 0 3 3 3 0 Rtf2 RING-finger NinG PF05766.12 ORY99321.1 - 1.6 8.7 10.6 1 9.3 0.5 2.3 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DNA_pol3_a_NII PF11490.8 ORY99321.1 - 3 7.8 0.0 3 7.8 0.0 3.2 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus II TERB2 PF15101.6 ORY99321.1 - 3.4 7.7 6.6 3.1 7.8 3.2 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Spt20 PF12090.8 ORY99321.1 - 4.2 6.9 11.4 4 7.0 9.8 1.7 1 1 0 1 1 1 0 Spt20 family DUF4820 PF16091.5 ORY99321.1 - 4.3 6.6 9.3 0.62 9.4 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) V_ATPase_I PF01496.19 ORY99322.1 - 0 1092.8 0.4 0 1092.6 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2730 PF10805.8 ORY99322.1 - 6.5 6.9 5.2 13 5.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) UPF0220 PF05255.11 ORY99326.1 - 2.9e-42 144.0 0.9 3.1e-42 143.9 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) SPX PF03105.19 ORY99328.1 - 1.2e-52 180.1 18.1 1.9e-52 179.5 18.1 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 ORY99328.1 - 3.3e-07 30.3 7.0 6.5e-07 29.4 7.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY99328.1 - 4.5e-06 26.4 7.1 9.2e-06 25.4 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY99328.1 - 5.2e-06 26.2 6.7 9.4e-06 25.4 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY99328.1 - 1.2e-05 25.0 8.7 2.5e-05 24.0 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY99328.1 - 1.5e-05 25.3 8.8 2.9e-05 24.3 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY99328.1 - 0.00012 22.0 9.8 0.00016 21.6 8.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY99328.1 - 0.00075 19.4 10.3 0.003 17.5 10.0 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY99328.1 - 0.0026 17.6 8.9 0.0064 16.3 8.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Antimicrobial18 PF08130.11 ORY99328.1 - 0.12 12.5 3.4 0.12 12.5 0.0 2.6 3 0 0 3 3 3 0 Type A lantibiotic family zf-RING_10 PF16685.5 ORY99328.1 - 0.18 12.0 4.2 0.48 10.6 4.2 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORY99328.1 - 0.73 10.2 8.0 2.4 8.5 8.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 ORY99328.1 - 0.86 9.7 3.1 2.9 8.0 1.7 2.3 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_4 PF14570.6 ORY99328.1 - 0.96 9.3 8.4 0.17 11.7 4.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Peptidase_M48 PF01435.18 ORY99329.1 - 8e-17 61.7 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Ras PF00071.22 ORY99330.1 - 2.6e-59 199.4 0.1 3e-59 199.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY99330.1 - 7.9e-21 74.5 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY99330.1 - 1.5e-08 34.3 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY99330.1 - 0.00012 21.7 0.4 0.00015 21.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY99330.1 - 0.00025 21.0 0.4 0.38 10.7 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 ORY99330.1 - 0.0039 17.2 0.0 0.0072 16.3 0.0 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 ORY99330.1 - 0.011 15.0 0.0 3.2 6.8 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 ORY99330.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORY99330.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase 2Fe-2S_thioredx PF01257.19 ORY99330.1 - 0.057 13.3 0.1 0.083 12.8 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Ras PF00071.22 ORY99331.1 - 5.5e-55 185.4 0.2 6.3e-55 185.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY99331.1 - 2.5e-20 72.9 0.0 4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY99331.1 - 8.9e-08 31.8 0.2 9.8e-08 31.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY99331.1 - 9.8e-07 28.5 0.2 2.4e-06 27.2 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY99331.1 - 0.00014 21.9 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY99331.1 - 0.00015 21.7 1.5 0.11 12.4 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 ORY99331.1 - 0.00095 18.4 0.1 0.34 10.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 ORY99331.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain LRR_4 PF12799.7 ORY99334.1 - 0.038 14.4 12.9 0.34 11.4 0.5 5.5 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY99334.1 - 0.041 13.8 0.2 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.6 ORY99334.1 - 1.1 9.0 8.6 4.1 7.3 0.3 4.5 5 0 0 5 5 5 0 Leucine rich repeat Bax1-I PF01027.20 ORY99335.1 - 9.4e-26 90.9 14.8 1.3e-25 90.5 14.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CPP1-like PF11833.8 ORY99335.1 - 0.0085 15.8 2.1 0.0085 15.8 2.1 2.0 2 0 0 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pkinase PF00069.25 ORY99336.1 - 2.3e-70 237.0 0.0 2.9e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99336.1 - 2e-33 115.8 0.0 5.1e-33 114.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase ABC1 PF03109.16 ORY99336.1 - 0.00016 21.8 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Kinase-like PF14531.6 ORY99336.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY99336.1 - 0.01 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY99336.1 - 0.012 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ORY99336.1 - 0.019 14.6 0.1 0.07 12.7 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 ORY99336.1 - 0.088 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Amidohydro_2 PF04909.14 ORY99337.1 - 1.4e-30 107.1 0.0 1.8e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase COX17 PF05051.13 ORY99337.1 - 0.19 12.1 0.2 0.34 11.3 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) B12D PF06522.11 ORY99338.1 - 0.00037 20.2 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-RVT PF13966.6 ORY99340.1 - 1.3e-05 25.8 0.6 1.6e-05 25.5 0.6 1.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CTU2 PF10288.9 ORY99343.1 - 3.9e-18 65.7 2.5 3.9e-18 65.7 2.5 1.8 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 ORY99343.1 - 0.034 13.9 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 PP-loop family Bacillus_HBL PF05791.11 ORY99343.1 - 0.079 12.8 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) zf-C3HC4_3 PF13920.6 ORY99343.1 - 2.6 8.0 7.1 2 8.4 1.1 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) I-set PF07679.16 ORY99344.1 - 1.2e-05 25.3 0.4 0.17 12.0 0.0 5.6 6 0 0 6 6 6 1 Immunoglobulin I-set domain CE2_N PF17996.1 ORY99344.1 - 0.15 12.0 0.0 0.51 10.4 0.0 1.9 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Neuromodulin PF06614.11 ORY99345.1 - 1.6 8.8 6.2 2.2 8.4 6.2 1.3 1 0 0 1 1 1 0 Neuromodulin KASH PF10541.9 ORY99347.1 - 2.1 8.7 7.4 2.1 8.7 0.5 2.1 2 0 0 2 2 2 0 Nuclear envelope localisation domain Ribosomal_L11 PF00298.19 ORY99349.1 - 3.8e-31 107.4 0.6 5.9e-31 106.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 ORY99349.1 - 7.5e-25 86.6 0.6 1.5e-24 85.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DUF809 PF05663.11 ORY99350.1 - 0.033 14.3 1.0 0.033 14.3 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF809) YqzM PF14141.6 ORY99350.1 - 0.12 12.4 2.1 0.17 11.9 2.1 1.3 1 0 0 1 1 1 0 YqzM-like protein Helo_like_N PF17111.5 ORY99351.1 - 0.0035 16.7 0.1 0.0092 15.4 0.1 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SlyX PF04102.12 ORY99351.1 - 0.0053 17.3 3.9 0.18 12.4 2.3 3.0 3 0 0 3 3 2 1 SlyX Spc7 PF08317.11 ORY99351.1 - 0.0072 15.2 5.9 0.012 14.6 4.0 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein AKNA PF12443.8 ORY99351.1 - 0.017 15.8 0.3 0.1 13.2 0.0 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor NPV_P10 PF05531.12 ORY99351.1 - 0.02 15.3 2.1 0.18 12.3 0.4 3.1 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3829 PF12889.7 ORY99351.1 - 0.04 13.4 3.1 0.1 12.1 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF4665 PF15679.5 ORY99351.1 - 0.081 13.6 2.1 0.27 11.9 2.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) CCDC-167 PF15188.6 ORY99351.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 CENP-F_leu_zip PF10473.9 ORY99351.1 - 0.13 12.3 10.4 0.086 12.9 7.0 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3907 PF13047.6 ORY99351.1 - 0.24 11.4 2.3 0.64 10.0 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3907) DUF1664 PF07889.12 ORY99351.1 - 0.24 11.4 6.2 0.41 10.7 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 ORY99351.1 - 0.4 11.0 9.3 4 7.7 9.3 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 KxDL PF10241.9 ORY99351.1 - 0.46 10.8 4.9 0.19 12.0 1.8 2.0 2 0 0 2 2 1 0 Uncharacterized conserved protein DUF3958 PF13125.6 ORY99351.1 - 1.3 9.3 8.0 0.14 12.4 1.1 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF3958) ATG16 PF08614.11 ORY99351.1 - 2.4 8.3 13.7 4.6 7.4 6.5 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Prominin PF05478.11 ORY99351.1 - 2.6 5.9 5.0 2.7 5.8 3.1 1.7 1 1 1 2 2 2 0 Prominin Fib_alpha PF08702.10 ORY99351.1 - 8.1 6.6 9.3 4.9 7.3 3.4 2.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GPI-anchored PF10342.9 ORY99352.1 - 3.5e-06 27.7 0.2 5.8e-06 27.0 0.2 1.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4499 PF14934.6 ORY99353.1 - 5.4e-13 49.1 0.1 9.9e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 ORY99353.1 - 1.8e-12 47.7 0.0 2.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) RhoGAP PF00620.27 ORY99354.1 - 3e-10 40.1 0.3 3e-10 40.1 0.3 2.6 3 0 0 3 3 3 1 RhoGAP domain DEP PF00610.21 ORY99354.1 - 5.1e-08 32.9 0.0 1.2e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 ORY99354.1 - 4.7e-07 30.0 3.8 7.8e-07 29.3 0.9 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Mus7 PF09462.10 ORY99354.1 - 0.035 13.0 4.3 0.065 12.1 4.3 1.4 1 0 0 1 1 1 0 Mus7/MMS22 family BAR_3 PF16746.5 ORY99354.1 - 0.25 11.0 11.1 1.4 8.6 11.0 2.2 1 1 0 1 1 1 0 BAR domain of APPL family RNA_polI_A14 PF08203.11 ORY99354.1 - 0.44 11.3 0.1 0.44 11.3 0.1 3.7 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 DUF16 PF01519.16 ORY99354.1 - 0.67 10.5 9.7 0.21 12.1 4.7 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 DNA_pol3_a_NII PF11490.8 ORY99354.1 - 2.3 8.1 6.7 0.22 11.4 1.5 2.0 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II LEA_2 PF03168.13 ORY99356.1 - 0.022 15.3 0.2 0.055 14.0 0.0 1.8 2 1 0 2 2 2 0 Late embryogenesis abundant protein PH PF00169.29 ORY99357.1 - 1.6e-12 47.8 0.0 1.8e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 ORY99357.1 - 9.6e-06 26.0 0.0 3e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Spt5_N PF11942.8 ORY99357.1 - 0.58 11.2 14.6 1 10.4 4.0 3.6 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 ORY99357.1 - 1.4 7.1 4.8 3.3 5.9 4.8 1.5 1 0 0 1 1 1 0 CDC45-like protein Adaptin_N PF01602.20 ORY99359.1 - 6.6e-139 463.8 9.3 7.7e-139 463.6 9.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ORY99359.1 - 7.1e-15 55.3 2.1 7.1e-15 55.3 2.1 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORY99359.1 - 5.7e-08 33.0 10.0 8.1e-08 32.5 0.3 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY99359.1 - 7.3e-05 23.1 2.6 1.1 9.7 0.0 4.4 4 1 2 6 6 6 3 HEAT repeats RIX1 PF08167.12 ORY99359.1 - 0.013 15.3 0.2 0.38 10.5 0.1 3.3 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Mu-like_Pro PF10123.9 ORY99359.1 - 0.023 14.2 0.5 0.81 9.2 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage I protein HEAT PF02985.22 ORY99359.1 - 0.39 11.1 4.4 1.3e+02 3.3 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat RICTOR_M PF14666.6 ORY99359.1 - 0.53 10.1 2.4 1.1 9.0 0.1 2.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain PPL5 PF18168.1 ORY99360.1 - 0.0054 16.1 0.9 0.0064 15.8 0.9 1.2 1 0 0 1 1 1 1 Prim-pol family 5 Suf PF05843.14 ORY99360.1 - 0.011 15.8 4.1 0.011 15.8 4.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 ORY99360.1 - 0.016 14.8 19.5 0.022 14.4 19.5 1.4 1 0 0 1 1 1 0 Spt20 family Zip PF02535.22 ORY99360.1 - 0.018 14.3 2.5 0.022 14.0 2.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 ORY99360.1 - 0.036 13.8 1.4 0.049 13.4 1.4 1.2 1 0 0 1 1 1 0 Connexin RAM PF15320.6 ORY99360.1 - 0.054 14.1 8.7 0.097 13.3 8.7 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein DUF2722 PF10846.8 ORY99360.1 - 0.094 11.6 18.7 0.1 11.5 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 ORY99360.1 - 0.1 12.7 3.0 0.11 12.6 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 ORY99360.1 - 0.11 11.2 6.5 0.12 11.2 6.5 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 ORY99360.1 - 0.28 11.8 12.9 0.37 11.4 12.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Coilin_N PF15862.5 ORY99360.1 - 0.34 10.7 10.7 0.02 14.7 5.9 1.5 2 0 0 2 2 1 0 Coilin N-terminus CSG2 PF16965.5 ORY99360.1 - 0.39 9.6 0.8 0.52 9.2 0.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator EMC3_TMCO1 PF01956.16 ORY99360.1 - 0.57 9.9 7.6 1.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CobT PF06213.12 ORY99360.1 - 1.1 8.5 13.2 1.4 8.2 13.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT EOS1 PF12326.8 ORY99360.1 - 1.1 9.1 2.7 1.8 8.5 2.7 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF3464 PF11947.8 ORY99360.1 - 1.7 8.4 6.9 2.9 7.6 6.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4407 PF14362.6 ORY99360.1 - 1.9 7.8 8.7 1.1 8.5 4.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4175 PF13779.6 ORY99360.1 - 8.2 4.2 19.2 10 3.9 19.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.14 ORY99361.1 - 7e-170 566.4 15.9 1.2e-142 476.4 3.9 2.0 1 1 1 2 2 2 2 CDC45-like protein DUF4200 PF13863.6 ORY99364.1 - 0.018 15.5 11.3 0.018 15.5 11.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 ORY99364.1 - 2.1 8.8 49.2 3.2 8.3 16.1 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 ORY99364.1 - 7.6 5.8 37.0 0.51 9.6 20.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 ORY99364.1 - 8 5.7 45.7 0.4 9.9 5.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) NDK PF00334.19 ORY99365.1 - 0.00029 20.8 0.3 0.042 13.9 0.3 3.1 1 1 0 1 1 1 1 Nucleoside diphosphate kinase SPX PF03105.19 ORY99365.1 - 1.4 8.8 18.3 2 8.2 18.3 1.3 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 ORY99365.1 - 3.6 7.5 12.2 4 7.3 12.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 ORY99365.1 - 6.3 5.9 28.0 9.1 5.4 28.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Dicty_REP PF05086.12 ORY99365.1 - 7.2 4.5 9.7 9.3 4.1 9.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UPF0014 PF03649.13 ORY99366.1 - 3.4e-66 223.0 20.8 4.1e-66 222.8 20.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) PIG-F PF06699.11 ORY99366.1 - 3.6 7.7 11.1 46 4.1 11.1 2.3 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F Ribosomal_S28e PF01200.18 ORY99367.1 - 5.6e-34 115.9 1.4 6.3e-34 115.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORY99367.1 - 0.041 14.2 0.0 0.042 14.2 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal LRR_4 PF12799.7 ORY99368.1 - 5.6e-15 55.2 9.2 2.1e-05 24.8 5.4 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY99368.1 - 7.2e-13 48.1 15.0 2.1e-09 37.0 9.5 3.7 1 1 3 4 4 4 3 Leucine rich repeat Acyltransferase PF01553.21 ORY99368.1 - 1.4e-09 37.6 0.0 8.9e-09 35.1 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase LRR_9 PF14580.6 ORY99368.1 - 1.9e-05 24.2 2.3 0.16 11.4 0.1 2.9 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 ORY99368.1 - 0.047 14.2 11.8 17 6.4 0.7 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY99368.1 - 0.047 13.7 10.7 33 4.9 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich repeat VHS PF00790.19 ORY99369.1 - 1.7e-33 115.4 0.1 1.7e-29 102.5 0.0 3.1 3 0 0 3 3 3 2 VHS domain Alpha_adaptinC2 PF02883.20 ORY99369.1 - 1.8e-20 73.3 0.3 8.5e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 ORY99369.1 - 0.00063 20.0 1.5 0.0019 18.5 1.5 1.9 1 0 0 1 1 1 1 GAT domain TTL PF03133.15 ORY99370.1 - 1.3e-52 178.8 1.7 2.3e-52 177.9 1.7 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SET PF00856.28 ORY99370.1 - 0.0014 19.0 0.1 0.0038 17.6 0.1 1.7 1 0 0 1 1 1 1 SET domain Transposase_1 PF01359.18 ORY99370.1 - 0.04 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Transposase (partial DDE domain) TPK_catalytic PF04263.16 ORY99371.1 - 1.4e-36 125.2 0.5 5.9e-36 123.2 0.4 1.8 1 1 1 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 ORY99371.1 - 1.4e-20 72.7 0.0 2.7e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF3627 PF12299.8 ORY99371.1 - 0.13 12.4 0.7 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) zf-C2H2 PF00096.26 ORY99373.1 - 1e-13 50.9 11.1 1.6e-06 28.2 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY99373.1 - 1e-10 41.5 18.6 3.9e-07 30.2 5.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY99373.1 - 1.6e-08 34.6 8.5 0.00074 20.2 1.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY99373.1 - 0.00093 19.4 0.1 0.027 14.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY99373.1 - 0.0026 18.4 0.4 0.047 14.3 0.0 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORY99373.1 - 0.0093 16.0 8.0 0.35 10.9 1.3 2.9 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY99373.1 - 0.024 14.6 5.8 0.46 10.5 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 ORY99373.1 - 0.032 14.7 2.3 1.6 9.3 0.1 2.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DUF2225 PF09986.9 ORY99373.1 - 0.04 13.6 0.5 0.05 13.3 0.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf_UBZ PF18439.1 ORY99373.1 - 0.075 12.6 0.7 4.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 ORY99373.1 - 0.1 12.5 0.4 11 6.0 0.0 2.5 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-Di19 PF05605.12 ORY99373.1 - 0.13 12.6 3.3 0.3 11.4 3.3 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CBM_14 PF01607.24 ORY99374.1 - 7.8e-09 35.6 1.1 7.8e-09 35.6 1.1 1.3 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain MutS_V PF00488.21 ORY99375.1 - 1.9e-82 275.8 0.4 3.6e-82 275.0 0.4 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY99375.1 - 3e-37 128.7 2.2 3e-37 128.7 2.2 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 ORY99375.1 - 1.4e-19 70.7 1.5 3.1e-19 69.6 0.2 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ORY99375.1 - 6.3e-16 58.5 3.2 1.6e-15 57.2 3.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 ORY99375.1 - 3e-14 53.2 0.0 8.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 ORY99375.1 - 0.019 14.5 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain LSM14 PF12701.7 ORY99376.1 - 2.8e-31 107.4 0.0 5.3e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 ORY99376.1 - 1e-15 58.5 6.4 1e-15 58.5 6.4 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 ORY99376.1 - 4.7e-07 29.9 0.0 8.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 ORY99376.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 LSM domain GRP PF07172.11 ORY99376.1 - 0.43 11.3 14.4 0.088 13.5 10.5 1.9 2 0 0 2 2 2 0 Glycine rich protein family Xan_ur_permease PF00860.20 ORY99377.1 - 1.1e-63 215.3 41.8 5.5e-62 209.7 41.8 2.0 1 1 0 1 1 1 1 Permease family RTX PF02382.15 ORY99377.1 - 0.00053 19.8 2.0 0.00094 19.0 2.0 1.3 1 0 0 1 1 1 1 N-terminal domain in RTX protein MASE5 PF17178.4 ORY99377.1 - 0.0087 15.9 6.4 0.38 10.6 4.2 2.7 2 0 0 2 2 2 2 Membrane-associated sensor Vma12 PF11712.8 ORY99377.1 - 8.3 6.5 6.9 2e+02 2.0 6.9 2.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CLZ PF16526.5 ORY99378.1 - 0.0018 18.6 1.1 0.0022 18.3 1.1 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MIP-T3_C PF17749.1 ORY99378.1 - 0.0021 18.1 2.2 0.0021 18.0 2.2 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region DUF3450 PF11932.8 ORY99378.1 - 0.0051 16.1 0.8 0.0058 16.0 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Eno-Rase_FAD_bd PF07055.12 ORY99378.1 - 0.012 16.0 0.9 0.018 15.4 0.9 1.3 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DUF948 PF06103.11 ORY99378.1 - 0.051 13.8 0.5 0.056 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spc24 PF08286.11 ORY99378.1 - 0.17 12.1 3.9 0.18 12.1 3.9 1.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PrmA PF06325.13 ORY99379.1 - 1.9e-15 57.0 0.0 2.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY99379.1 - 1.9e-13 50.3 0.0 2.5e-13 49.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 ORY99379.1 - 6.9e-09 35.7 0.1 1.4e-07 31.4 0.0 2.5 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 ORY99379.1 - 1.5e-07 31.3 0.3 3.1e-07 30.3 0.1 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY99379.1 - 3.4e-07 30.9 0.1 9.2e-07 29.5 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY99379.1 - 1.8e-05 24.4 0.0 2.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 ORY99379.1 - 0.00082 20.0 0.0 0.002 18.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY99379.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY99379.1 - 0.0012 19.6 0.1 0.0032 18.2 0.1 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY99379.1 - 0.0064 16.5 0.0 0.0091 16.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY99379.1 - 0.008 16.1 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 ORY99379.1 - 0.02 14.2 0.1 0.022 14.0 0.1 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_16 PF10294.9 ORY99379.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.5 1 1 0 1 1 1 0 Lysine methyltransferase N6_Mtase PF02384.16 ORY99379.1 - 0.029 13.7 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase PCMT PF01135.19 ORY99379.1 - 0.037 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AIRS_C PF02769.22 ORY99379.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 AIR synthase related protein, C-terminal domain N6_N4_Mtase PF01555.18 ORY99379.1 - 0.13 12.0 0.2 12 5.5 0.1 2.1 2 0 0 2 2 2 0 DNA methylase PALP PF00291.25 ORY99380.1 - 1.6e-49 168.9 0.0 2e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORY99380.1 - 1e-18 67.5 0.0 2e-09 37.7 0.0 3.5 3 0 0 3 3 3 2 CBS domain GrpB PF04229.14 ORY99380.1 - 0.037 14.2 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 GrpB protein Myb_DNA-binding PF00249.31 ORY99381.1 - 0.0033 17.6 0.4 0.0055 16.9 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY99381.1 - 0.0074 16.5 0.1 0.017 15.4 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain CS PF04969.16 ORY99383.1 - 2.5e-08 34.8 0.7 3.5e-08 34.4 0.7 1.2 1 0 0 1 1 1 1 CS domain LEA_2 PF03168.13 ORY99385.1 - 7.3e-05 23.2 0.0 0.00013 22.4 0.0 1.4 1 1 0 1 1 1 1 Late embryogenesis abundant protein HIT PF01230.23 ORY99386.1 - 1.1e-23 83.8 0.1 1.5e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORY99386.1 - 8.3e-12 45.6 0.4 1.5e-11 44.8 0.4 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORY99386.1 - 1.4e-06 28.2 2.1 2.7e-06 27.2 2.1 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF1772 PF08592.11 ORY99387.1 - 8.2e-18 65.0 2.4 9.8e-18 64.8 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MerC PF03203.14 ORY99387.1 - 0.032 14.7 0.1 0.045 14.2 0.1 1.4 1 1 0 1 1 1 0 MerC mercury resistance protein UCH PF00443.29 ORY99388.1 - 1.5e-29 103.3 0.0 1.5e-29 103.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY99388.1 - 5e-17 62.5 0.0 1e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VASt PF16016.5 ORY99391.1 - 2.8e-32 112.3 0.1 6e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 ORY99391.1 - 6.7e-20 71.8 1.7 1.2e-19 71.0 1.7 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORY99391.1 - 1.9e-09 37.9 0.1 4.9e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 PH domain Sec6 PF06046.13 ORY99391.1 - 0.016 13.6 0.1 0.025 13.0 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 Cor1 PF04803.12 ORY99391.1 - 0.15 12.2 2.9 0.23 11.7 1.3 2.1 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Rrn6 PF10214.9 ORY99392.1 - 0.00017 20.3 14.1 0.0002 20.1 14.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Plasmodium_Vir PF05795.11 ORY99392.1 - 0.0013 18.3 4.0 0.0016 17.9 4.0 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein YukC PF10140.9 ORY99392.1 - 0.0038 16.1 0.9 0.0038 16.1 0.9 2.0 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Ndc1_Nup PF09531.10 ORY99392.1 - 0.089 11.5 10.1 0.14 10.8 10.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TAF4 PF05236.14 ORY99392.1 - 0.14 11.9 26.7 0.29 10.8 26.2 1.5 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PI3K_1B_p101 PF10486.9 ORY99392.1 - 0.15 9.8 12.9 0.2 9.4 12.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 ORY99392.1 - 0.16 9.1 13.6 0.19 8.8 13.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 ORY99392.1 - 0.17 11.2 9.2 0.29 10.4 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lin-8 PF03353.15 ORY99392.1 - 0.21 11.1 12.6 0.29 10.6 12.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1682 PF07946.14 ORY99392.1 - 0.44 9.7 15.2 0.7 9.0 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Dicty_REP PF05086.12 ORY99392.1 - 0.8 7.6 10.0 1 7.2 10.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LCD1 PF09798.9 ORY99392.1 - 0.99 7.8 9.8 1.4 7.4 9.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Sec62 PF03839.16 ORY99392.1 - 0.99 8.9 3.8 1.8 8.0 3.8 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 XRN_M PF17846.1 ORY99392.1 - 1 8.2 7.6 1.4 7.8 7.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain SLC12 PF03522.15 ORY99392.1 - 1.3 8.0 11.6 1.8 7.5 11.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 ORY99392.1 - 1.6 8.3 19.0 2.2 7.8 19.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) HSD3 PF15244.6 ORY99392.1 - 1.6 8.2 19.3 2.6 7.5 19.3 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Ecl1 PF12855.7 ORY99392.1 - 1.6 9.9 18.5 0.34 12.0 14.9 1.8 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins ALMT PF11744.8 ORY99392.1 - 1.9 7.2 9.3 3.1 6.5 9.3 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Dynactin_p62 PF05502.13 ORY99392.1 - 2.7 6.7 14.9 3.8 6.2 14.9 1.1 1 0 0 1 1 1 0 Dynactin p62 family Hid1 PF12722.7 ORY99392.1 - 3.4 5.7 19.9 4.6 5.2 19.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 ORY99392.1 - 4.3 7.8 9.8 7 7.2 9.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Radial_spoke_3 PF06098.11 ORY99392.1 - 4.8 6.4 20.7 8.5 5.6 20.7 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 NeA_P2 PF12312.8 ORY99393.1 - 0.011 15.2 1.0 0.017 14.6 1.0 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CAP_N PF01213.19 ORY99393.1 - 0.046 13.2 2.6 0.059 12.8 2.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-HC5HC2H_2 PF13832.6 ORY99394.1 - 3.1e-23 82.0 7.6 3.1e-23 82.0 7.6 4.6 5 0 0 5 5 5 2 PHD-zinc-finger like domain BAH PF01426.18 ORY99394.1 - 8e-18 64.5 0.0 1.9e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 ORY99394.1 - 6.1e-15 55.2 5.6 6.1e-15 55.2 5.6 5.8 5 3 1 6 6 6 1 PHD-like zinc-binding domain PHD PF00628.29 ORY99394.1 - 4.6e-13 48.8 61.2 5.7e-08 32.5 12.5 5.7 5 1 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 ORY99394.1 - 2.1e-09 36.8 1.8 2.1e-09 36.8 1.8 4.9 5 0 0 5 5 5 3 PHD-finger GATA PF00320.27 ORY99394.1 - 1.4e-06 27.8 6.6 1.4e-06 27.8 6.6 3.3 2 1 0 2 2 2 1 GATA zinc finger C1_1 PF00130.22 ORY99394.1 - 0.015 15.2 1.4 0.015 15.2 1.4 6.6 6 2 1 7 7 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 ORY99394.1 - 0.05 13.8 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Eaf7 PF07904.13 ORY99394.1 - 0.42 11.0 2.6 2.7 8.4 2.6 2.4 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 DUF5470 PF17564.2 ORY99394.1 - 0.5 10.6 2.8 1.4 9.1 2.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5470) C1_2 PF03107.16 ORY99394.1 - 7.3 7.0 46.0 0.2 12.0 0.2 6.5 7 0 0 7 7 6 0 C1 domain DUF92 PF01940.16 ORY99395.1 - 3.3e-76 255.8 7.4 3.8e-76 255.6 7.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Phage_holin_3_6 PF07332.11 ORY99395.1 - 0.0054 16.7 4.8 0.97 9.5 1.3 2.4 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III Proteasome PF00227.26 ORY99396.1 - 1.8e-62 210.2 0.1 2.2e-62 209.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY99396.1 - 7.3e-14 51.1 0.1 1.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_M17 PF00883.21 ORY99397.1 - 1.9e-63 214.7 0.0 3.4e-63 213.8 0.0 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain ASXH PF13919.6 ORY99398.1 - 3.2e-17 62.8 3.9 1e-16 61.2 0.6 2.6 2 1 0 2 2 2 1 Asx homology domain GHMP_kinases_C PF08544.13 ORY99398.1 - 0.039 14.3 0.3 0.087 13.2 0.3 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal AAA PF00004.29 ORY99399.1 - 1.4e-37 129.0 0.0 2.7e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY99399.1 - 4.5e-11 42.4 0.0 1.1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY99399.1 - 1.5e-06 28.0 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY99399.1 - 2.1e-06 28.3 0.3 2.2e-05 24.9 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY99399.1 - 3.1e-06 27.5 0.3 0.0017 18.6 0.1 3.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY99399.1 - 4.5e-06 26.7 0.1 2.6e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORY99399.1 - 6.2e-06 26.3 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY99399.1 - 1.7e-05 25.0 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORY99399.1 - 0.00017 22.1 0.0 0.00032 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 ORY99399.1 - 0.00017 21.0 0.2 1.2 8.5 0.0 3.4 3 1 1 4 4 4 2 Bacterial TniB protein AAA_33 PF13671.6 ORY99399.1 - 0.00043 20.4 0.0 0.00075 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY99399.1 - 0.00065 19.1 0.2 0.0016 17.9 0.1 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY99399.1 - 0.00068 20.0 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 ORY99399.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY99399.1 - 0.002 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad17 PF03215.15 ORY99399.1 - 0.0029 17.6 0.1 0.0086 16.0 0.1 1.8 2 1 0 2 2 1 1 Rad17 P-loop domain DUF815 PF05673.13 ORY99399.1 - 0.0029 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.6 ORY99399.1 - 0.004 17.0 0.2 0.32 10.7 0.2 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 ORY99399.1 - 0.0049 17.1 0.0 0.0095 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY99399.1 - 0.0056 16.3 0.4 0.052 13.1 0.4 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 ORY99399.1 - 0.0057 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 ORY99399.1 - 0.0061 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 ORY99399.1 - 0.0062 17.1 0.0 0.015 15.8 0.0 1.8 2 1 0 2 2 1 1 ABC transporter TIP49 PF06068.13 ORY99399.1 - 0.0076 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Bac_DnaA PF00308.18 ORY99399.1 - 0.0076 16.1 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_7 PF12775.7 ORY99399.1 - 0.0079 15.7 0.2 0.017 14.6 0.0 1.7 2 1 0 2 2 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 ORY99399.1 - 0.01 15.8 0.0 0.075 12.9 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 ORY99399.1 - 0.01 15.2 0.0 0.31 10.3 0.0 2.2 1 1 1 2 2 2 0 KaiC Zeta_toxin PF06414.12 ORY99399.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Guanylate_kin PF00625.21 ORY99399.1 - 0.015 15.0 0.0 0.16 11.6 0.0 2.5 2 1 1 3 3 3 0 Guanylate kinase AAA_17 PF13207.6 ORY99399.1 - 0.022 15.2 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY99399.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 ORY99399.1 - 0.031 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 ORY99399.1 - 0.034 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.12 ORY99399.1 - 0.041 13.7 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 ORY99399.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 ORY99399.1 - 0.089 12.0 0.1 2.3 7.4 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Viral_helicase1 PF01443.18 ORY99399.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Hydin_ADK PF17213.3 ORY99399.1 - 0.15 12.3 0.1 1.9 8.7 0.0 2.4 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain NB-ARC PF00931.22 ORY99399.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SNF2_N PF00176.23 ORY99400.1 - 4.6e-40 137.4 0.1 7.6e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY99400.1 - 1.9e-10 41.1 0.7 3.9e-10 40.0 0.7 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_S26e PF01283.19 ORY99401.1 - 6.3e-54 181.0 11.0 6.9e-54 180.9 11.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Pkinase PF00069.25 ORY99403.1 - 3.1e-71 239.8 0.0 3.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99403.1 - 6.3e-42 143.6 0.0 9.2e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY99403.1 - 9.3e-10 38.3 0.0 1.6e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY99403.1 - 0.00034 19.5 0.0 0.00053 18.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORY99403.1 - 0.0026 17.4 0.1 0.35 10.5 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY99403.1 - 0.031 13.6 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY99403.1 - 0.065 13.2 0.1 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family PAT1 PF09770.9 ORY99404.1 - 1.7e-127 426.9 60.9 1.9e-115 387.1 47.5 3.8 2 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 zf-AN1 PF01428.16 ORY99405.1 - 2.6e-21 75.5 34.5 5e-11 42.6 10.0 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORY99405.1 - 0.0011 19.3 22.6 0.0099 16.2 7.4 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Neogenin_C PF06583.12 ORY99405.1 - 0.0078 16.1 0.8 0.0094 15.8 0.8 1.1 1 0 0 1 1 1 1 Neogenin C-terminus DUF4602 PF15375.6 ORY99405.1 - 1.4 9.3 7.3 11 6.4 4.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4602) Ank_2 PF12796.7 ORY99406.1 - 1.1e-24 86.8 0.2 1.7e-12 47.8 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY99406.1 - 1.1e-19 68.4 4.2 0.00049 20.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 ORY99406.1 - 6.5e-18 64.6 1.9 3.1e-06 27.4 0.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY99406.1 - 2.2e-17 62.7 7.5 7.9e-06 26.1 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 ORY99406.1 - 1.8e-16 60.3 4.1 8.9e-08 32.5 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) AA_permease_2 PF13520.6 ORY99407.1 - 9.7e-70 235.5 36.3 1.2e-69 235.2 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY99407.1 - 4.5e-30 104.7 33.5 6.3e-30 104.2 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 ORY99408.1 - 1.4e-49 168.9 28.7 6.9e-44 150.2 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY99408.1 - 8.4e-11 41.4 27.6 2.3e-10 40.0 8.3 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORY99408.1 - 3.7e-05 22.8 17.8 0.0016 17.4 5.5 2.6 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 ORY99408.1 - 0.0017 16.7 0.3 0.0017 16.7 0.3 3.0 2 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family DUF1275 PF06912.11 ORY99408.1 - 0.25 11.2 28.4 1.1 9.1 9.7 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF1275) DUF1304 PF06993.12 ORY99408.1 - 1.4 8.9 17.3 1.4 8.9 5.5 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1304) DUF2070 PF09843.9 ORY99408.1 - 9.6 4.4 15.3 1 7.6 2.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) RNase_T PF00929.24 ORY99409.1 - 1e-28 101.0 0.0 2e-28 100.0 0.0 1.4 2 0 0 2 2 2 1 Exonuclease SAP PF02037.27 ORY99409.1 - 6.5e-05 22.6 3.2 0.0001 21.9 3.2 1.3 1 0 0 1 1 1 1 SAP domain DUF3514 PF12027.8 ORY99409.1 - 0.0025 17.6 0.1 0.0035 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3514) Imm44 PF15571.6 ORY99409.1 - 0.023 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 44 DUF5051 PF16473.5 ORY99409.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like HAD_2 PF13419.6 ORY99410.1 - 6.4e-09 36.1 0.0 9.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY99410.1 - 9.4e-08 32.6 0.0 2.4e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY99410.1 - 0.029 14.8 0.3 0.054 13.9 0.3 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY99410.1 - 0.12 12.4 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 HAD-hyrolase-like Lipase_GDSL_2 PF13472.6 ORY99411.1 - 5.7e-11 43.1 1.0 1.2e-10 42.0 1.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY99411.1 - 8.7e-11 42.2 0.0 1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SURF6 PF04935.12 ORY99412.1 - 2.8e-32 112.1 64.6 2.8e-32 112.1 64.6 2.9 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 ORY99412.1 - 1.9e-19 70.0 4.0 1.9e-19 70.0 4.0 7.2 4 1 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 DUF4097 PF13349.6 ORY99414.1 - 4.3e-09 36.1 1.2 1.3e-08 34.5 1.2 1.7 1 1 0 1 1 1 1 Putative adhesin Spt20 PF12090.8 ORY99414.1 - 7.4 6.1 13.5 14 5.2 13.5 1.4 1 0 0 1 1 1 0 Spt20 family FYRN PF05964.14 ORY99415.1 - 1.2e-18 66.7 0.3 2e-18 66.0 0.3 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY99415.1 - 4e-17 62.1 0.0 8.5e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus HNF-1_N PF04814.13 ORY99415.1 - 0.22 12.1 0.3 0.22 12.1 0.3 3.2 2 1 1 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus TFIID_20kDa PF03847.13 ORY99416.1 - 1.8e-35 121.3 0.7 2.3e-35 120.9 0.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 ORY99416.1 - 9.6e-05 22.6 0.1 0.00015 22.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY99416.1 - 0.00019 21.8 0.1 0.00028 21.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ORY99416.1 - 0.0099 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 ORY99416.1 - 0.049 13.8 0.1 0.085 13.0 0.1 1.4 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold CotH PF08757.11 ORY99417.1 - 1.1e-30 107.3 0.1 1.7e-30 106.7 0.1 1.1 1 0 0 1 1 1 1 CotH kinase protein DUF5435 PF17503.2 ORY99417.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5435) DUF3419 PF11899.8 ORY99418.1 - 1e-145 485.8 0.9 1.4e-145 485.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 ORY99418.1 - 4.3e-12 46.6 0.0 3.4e-09 37.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY99418.1 - 4.5e-11 42.9 0.0 4.2e-09 36.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY99418.1 - 3.1e-09 37.4 0.0 6.2e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 ORY99418.1 - 7.9e-09 35.2 0.0 1.1e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY99418.1 - 4.7e-08 33.7 0.0 3.5e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY99418.1 - 5e-07 29.6 0.0 6.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY99418.1 - 0.00058 19.4 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Cyclase_polyket PF04673.12 ORY99418.1 - 0.027 14.7 0.1 0.083 13.2 0.1 1.8 1 0 0 1 1 1 0 Polyketide synthesis cyclase PCMT PF01135.19 ORY99418.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 ORY99418.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Homeodomain PF00046.29 ORY99419.1 - 1.7e-09 37.4 1.2 3.2e-09 36.5 1.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY99419.1 - 0.00022 21.1 0.3 0.00046 20.0 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain CHD5 PF04420.14 ORY99419.1 - 0.063 13.1 2.0 0.076 12.9 0.3 1.8 1 1 1 2 2 2 0 CHD5-like protein lci PF12197.8 ORY99419.1 - 0.11 12.3 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein LRR_4 PF12799.7 ORY99420.1 - 0.00037 20.8 0.3 1.5 9.3 0.0 4.6 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY99420.1 - 0.16 12.1 7.1 50 4.3 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich repeat DEAD PF00270.29 ORY99421.1 - 1.2e-51 175.0 0.0 1e-49 168.7 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY99421.1 - 2.9e-25 88.7 0.0 7.9e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RasGEF PF00617.19 ORY99422.1 - 3.9e-44 151.0 2.2 8.4e-44 149.9 2.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY99422.1 - 8e-14 51.8 1.4 2.1e-13 50.4 0.1 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif Peptidase_M28 PF04389.17 ORY99423.1 - 1.3e-38 132.7 0.0 1.8e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 SARAF PF06682.12 ORY99424.1 - 0.0021 17.7 0.1 0.0038 16.9 0.0 1.4 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis TssO PF17561.2 ORY99424.1 - 0.033 14.3 0.3 0.033 14.3 0.3 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO Baculo_11_kDa PF06143.11 ORY99424.1 - 0.049 13.2 0.7 0.14 11.8 0.7 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family WBP-1 PF11669.8 ORY99424.1 - 0.065 13.9 0.6 0.065 13.9 0.6 2.3 1 1 1 2 2 2 0 WW domain-binding protein 1 Spore_III_AB PF09548.10 ORY99424.1 - 0.1 12.7 0.4 0.18 11.9 0.2 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TMIE PF16038.5 ORY99424.1 - 0.1 12.4 0.4 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 TMIE protein Shisa PF13908.6 ORY99424.1 - 0.14 12.4 7.5 1.1 9.4 7.5 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SIT PF15330.6 ORY99424.1 - 0.14 12.6 4.7 0.23 11.9 3.7 1.8 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT PAP_PilO PF06864.12 ORY99424.1 - 0.15 10.8 0.1 0.15 10.8 0.1 2.0 1 1 1 2 2 2 0 Pilin accessory protein (PilO) FERM_M PF00373.18 ORY99424.1 - 0.24 11.8 6.5 17 5.8 6.4 2.2 1 1 0 1 1 1 0 FERM central domain LSR PF05624.14 ORY99424.1 - 0.75 9.8 5.5 1.1 9.2 5.5 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) TPALS PF18178.1 ORY99424.1 - 0.75 9.2 2.3 1.2 8.5 0.7 1.9 1 1 1 2 2 2 0 TIR- and PNP-associating SLOG family SecE PF00584.20 ORY99424.1 - 2 8.4 5.9 1.4 8.9 3.7 1.7 1 1 1 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4834 PF16118.5 ORY99424.1 - 5.9 7.9 7.5 49 5.0 7.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) FAD_binding_3 PF01494.19 ORY99425.1 - 2e-70 237.8 0.0 1.5e-69 234.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY99425.1 - 6.6e-07 28.8 0.1 0.0094 15.2 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY99425.1 - 6.8e-05 22.6 0.1 0.079 12.5 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY99425.1 - 8.3e-05 23.1 0.2 0.068 13.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY99425.1 - 0.0028 16.4 0.0 0.045 12.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 ORY99425.1 - 0.028 13.5 0.1 0.18 10.8 0.0 2.2 2 1 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 ORY99425.1 - 0.028 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ORY99425.1 - 0.071 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 ORY99425.1 - 0.077 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY99425.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ORY99425.1 - 0.11 11.7 0.0 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY99425.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 ORY99425.1 - 0.15 12.6 0.0 0.51 10.8 0.0 2.1 1 1 0 1 1 1 0 XdhC Rossmann domain NAD_binding_10 PF13460.6 ORY99426.1 - 2.3e-15 56.9 0.3 3.3e-15 56.5 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY99426.1 - 8.9e-15 54.9 0.6 3.1e-08 33.5 0.6 2.0 2 0 0 2 2 2 2 NmrA-like family Sacchrp_dh_NADP PF03435.18 ORY99426.1 - 1.7e-06 28.3 0.4 3.5e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORY99426.1 - 5e-06 26.1 0.3 1.2e-05 24.9 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY99426.1 - 1.1e-05 25.8 0.3 5e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 ORY99426.1 - 0.00036 20.0 0.1 0.00074 19.0 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 ORY99426.1 - 0.00052 20.1 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORY99426.1 - 0.0027 18.1 0.1 0.0064 16.9 0.1 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 ORY99426.1 - 0.0032 17.7 0.1 0.0075 16.5 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 ORY99426.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY99426.1 - 0.041 13.0 0.0 2.2 7.3 0.0 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY99426.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY99426.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Rep_fac-A_C PF08646.10 ORY99427.1 - 4.6e-05 23.2 0.2 5.3e-05 23.0 0.2 1.0 1 0 0 1 1 1 1 Replication factor-A C terminal domain zf-FPG_IleRS PF06827.14 ORY99427.1 - 0.01 15.7 0.5 0.034 14.0 0.5 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zinc_ribbon_10 PF10058.9 ORY99427.1 - 0.12 12.1 0.6 0.12 12.1 0.6 1.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein FlhC PF05280.11 ORY99427.1 - 0.2 11.4 1.2 0.24 11.1 1.2 1.1 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) RF-1 PF00472.20 ORY99428.1 - 5e-15 55.4 2.3 1.7e-14 53.7 2.0 1.9 1 1 0 1 1 1 1 RF-1 domain Nup54 PF13874.6 ORY99428.1 - 0.038 14.1 1.0 0.077 13.1 1.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Dicty_REP PF05086.12 ORY99428.1 - 1.5 6.7 3.7 1.8 6.5 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF423 PF04241.15 ORY99429.1 - 3.3e-21 75.3 0.4 4.4e-21 74.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) F-box-like PF12937.7 ORY99430.1 - 2.8e-08 33.5 0.3 6.8e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY99430.1 - 0.00032 20.5 0.8 0.00079 19.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY99432.1 - 2.7e-06 27.2 1.0 3.8e-06 26.7 1.0 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY99432.1 - 0.0012 18.7 1.8 0.0026 17.6 1.8 1.5 1 1 0 1 1 1 1 F-box domain Peptidase_M41 PF01434.18 ORY99433.1 - 4e-67 225.8 0.0 5.9e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORY99433.1 - 9.8e-43 145.7 0.0 1.8e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY99433.1 - 3.4e-11 42.8 0.3 1e-10 41.2 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ORY99433.1 - 8e-07 29.4 0.0 3.1e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 ORY99433.1 - 0.0024 17.2 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 ORY99433.1 - 0.0038 17.6 0.2 0.099 13.0 0.2 2.5 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY99433.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY99433.1 - 0.0085 16.4 0.0 0.64 10.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY99433.1 - 0.01 15.8 0.0 0.039 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 ORY99433.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORY99433.1 - 0.054 13.6 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ORY99433.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY99433.1 - 0.2 11.0 0.3 0.45 9.9 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI adh_short PF00106.25 ORY99434.1 - 5.2e-20 71.7 0.0 4.4e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY99434.1 - 9.3e-09 35.2 0.0 5.5e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY99434.1 - 0.00024 20.6 0.0 0.00048 19.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY99434.1 - 0.00035 20.1 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 ORY99434.1 - 0.0071 16.3 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF826 PF05696.11 ORY99435.1 - 0.0063 16.6 1.2 4.6 7.4 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF826) DinB_2 PF12867.7 ORY99435.1 - 0.026 15.0 0.5 0.1 13.1 0.1 2.1 3 0 0 3 3 3 0 DinB superfamily V-ATPase_G_2 PF16999.5 ORY99435.1 - 0.032 14.6 0.8 0.41 11.1 1.3 2.5 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit FliX PF10768.9 ORY99435.1 - 0.087 13.3 1.0 0.2 12.2 1.0 1.6 1 0 0 1 1 1 0 Class II flagellar assembly regulator Rft-1 PF04506.13 ORY99436.1 - 6e-140 467.4 16.8 6.9e-140 467.2 16.8 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_C PF14667.6 ORY99436.1 - 0.00047 20.2 12.1 0.00047 20.2 12.1 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain GPW_gp25 PF04965.14 ORY99436.1 - 0.078 12.8 0.0 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Gene 25-like lysozyme RRM_1 PF00076.22 ORY99437.1 - 3.4e-17 62.0 0.0 4.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2613 PF11021.8 ORY99437.1 - 0.068 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Nup35_RRM_2 PF14605.6 ORY99437.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hydrolase_6 PF13344.6 ORY99438.1 - 1.1e-27 96.1 0.0 5.5e-27 93.8 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY99438.1 - 2.6e-16 59.5 0.0 5.7e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY99438.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY99438.1 - 9.5e-06 25.8 0.0 0.0089 16.1 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase CwfJ_C_1 PF04677.15 ORY99439.1 - 1.4e-27 96.0 0.1 2.6e-27 95.1 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ORY99439.1 - 3.3e-16 60.0 0.3 1e-15 58.4 0.1 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.6 ORY99439.1 - 1.7e-07 30.9 5.9 3.7e-07 29.9 5.9 1.6 1 0 0 1 1 1 1 Zinc knuckle HIT PF01230.23 ORY99439.1 - 0.0014 19.4 0.0 0.0032 18.2 0.0 1.6 1 0 0 1 1 1 1 HIT domain zf-CCHC PF00098.23 ORY99439.1 - 0.055 13.6 6.1 0.17 12.1 6.1 1.9 1 0 0 1 1 1 0 Zinc knuckle MMS1_N PF10433.9 ORY99440.1 - 1.8e-161 538.1 0.0 2.7e-161 537.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY99440.1 - 3.7e-93 312.4 0.0 3.1e-92 309.3 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region WD40 PF00400.32 ORY99440.1 - 0.13 13.2 0.0 11 7.0 0.0 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Fer2_3 PF13085.6 ORY99442.1 - 3.3e-32 110.7 0.0 5.4e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ORY99442.1 - 9.7e-10 38.9 8.3 9.7e-10 38.9 8.3 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORY99442.1 - 8.6e-07 29.3 9.4 8.6e-07 29.3 9.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY99442.1 - 4.2e-06 26.8 4.4 4.2e-06 26.8 4.4 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ORY99442.1 - 0.0017 18.9 6.2 0.0017 18.9 6.2 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ORY99442.1 - 0.003 17.5 2.6 0.0071 16.3 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 ORY99442.1 - 0.59 10.4 14.6 0.1 12.8 8.5 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 ORY99442.1 - 1.3 9.3 6.6 1.2 9.3 0.2 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Acyltransferase PF01553.21 ORY99443.1 - 3.7e-22 78.4 0.0 5.3e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Glyco_hydro_18 PF00704.28 ORY99444.1 - 2.6e-28 99.7 2.3 1.4e-27 97.3 2.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 ORY99444.1 - 1.4e-08 34.6 15.7 1.4e-08 34.6 15.7 2.7 1 1 1 2 2 2 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORY99444.1 - 0.35 11.1 8.1 0.081 13.1 3.1 2.3 1 1 0 2 2 2 0 Chitin binding Peritrophin-A domain SH3_1 PF00018.28 ORY99445.1 - 6.5e-16 57.7 0.3 1.3e-15 56.7 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY99445.1 - 1.5e-14 53.5 0.1 2.3e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY99445.1 - 5.3e-13 48.4 0.1 1e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps54_N PF10475.9 ORY99446.1 - 0.039 13.2 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Vps54_N PF10475.9 ORY99449.1 - 0.011 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex NUC129 PF08157.11 ORY99449.1 - 0.14 12.5 0.4 0.17 12.2 0.4 1.2 1 0 0 1 1 1 0 NUC129 domain Vps54_N PF10475.9 ORY99452.1 - 0.011 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex NUC129 PF08157.11 ORY99452.1 - 0.14 12.5 0.4 0.17 12.2 0.4 1.2 1 0 0 1 1 1 0 NUC129 domain Actin PF00022.19 ORY99456.1 - 6.5e-50 169.9 0.0 2.3e-49 168.1 0.0 1.8 1 1 1 2 2 2 1 Actin MreB_Mbl PF06723.13 ORY99456.1 - 4e-09 35.7 0.0 2e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Pkinase PF00069.25 ORY99457.1 - 1.3e-69 234.5 0.0 1.9e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99457.1 - 2e-27 96.1 0.0 3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY99457.1 - 2.3e-06 26.8 0.3 4.2e-06 26.0 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY99457.1 - 0.0049 16.8 1.2 0.01 15.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Menin PF05053.13 ORY99457.1 - 2.3 6.5 5.0 3.1 6.1 5.0 1.1 1 0 0 1 1 1 0 Menin DUF908 PF06012.12 ORY99458.1 - 0.028 13.8 3.4 0.029 13.8 3.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF2486 PF10667.9 ORY99458.1 - 0.52 10.5 13.8 0.55 10.4 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) TALPID3 PF15324.6 ORY99458.1 - 0.81 7.3 9.9 0.89 7.2 9.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target FAR1 PF03101.15 ORY99459.1 - 1.4e-05 25.7 2.2 5.1e-05 23.9 2.2 2.0 1 0 0 1 1 1 1 FAR1 DNA-binding domain RNR_Alpha PF17975.1 ORY99459.1 - 0.042 14.4 0.3 0.042 14.4 0.3 1.9 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain PAT1 PF09770.9 ORY99459.1 - 3.7 5.7 18.0 5.2 5.2 18.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L1 PF00687.21 ORY99460.1 - 3e-35 121.8 0.2 3.5e-35 121.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-U1 PF06220.12 ORY99461.1 - 2.5e-07 30.4 5.4 6.1e-07 29.1 5.4 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-CCCH PF00642.24 ORY99461.1 - 9.6e-07 28.6 2.0 9.6e-07 28.6 2.0 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY99461.1 - 0.0023 17.9 1.3 0.0066 16.5 1.3 1.8 1 0 0 1 1 1 1 Zinc finger domain AKAP95 PF04988.12 ORY99461.1 - 0.033 14.4 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-CCCH_4 PF18044.1 ORY99461.1 - 0.05 13.4 5.2 0.15 11.9 5.2 1.9 1 1 0 1 1 1 0 CCCH-type zinc finger zf-DBF PF07535.12 ORY99461.1 - 0.74 10.0 5.5 1.1 9.4 4.9 1.6 1 1 0 1 1 1 0 DBF zinc finger Ribosom_S12_S23 PF00164.25 ORY99462.1 - 1.9e-50 169.3 1.2 2.3e-50 169.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Complex1_LYR PF05347.15 ORY99463.1 - 2.2e-05 24.4 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Sec7 PF01369.20 ORY99464.1 - 7.4e-32 110.5 0.1 1.3e-31 109.8 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORY99464.1 - 1.7e-31 109.0 0.0 4.7e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY99464.1 - 0.006 17.1 0.0 0.038 14.5 0.0 2.2 1 1 0 1 1 1 1 PH domain Spore_III_AB PF09548.10 ORY99464.1 - 0.069 13.2 0.8 2.5 8.2 0.0 2.7 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) NST1 PF13945.6 ORY99464.1 - 0.45 10.6 5.3 2.4 8.2 0.2 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator Cwf_Cwc_15 PF04889.12 ORY99464.1 - 1.1 9.0 16.0 0.054 13.2 7.0 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 ORY99464.1 - 1.4 8.6 7.6 3.3 7.4 1.4 2.5 2 0 0 2 2 2 0 FAM176 family PPP4R2 PF09184.11 ORY99464.1 - 2.6 7.6 10.1 1.1 8.7 3.1 2.4 2 0 0 2 2 2 0 PPP4R2 RXT2_N PF08595.11 ORY99464.1 - 2.8 8.0 8.3 1.3 9.0 1.9 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIIC_delta PF12657.7 ORY99465.1 - 1.5e-17 64.1 0.0 7.8e-17 61.8 0.0 2.2 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 ORY99465.1 - 1e-06 28.6 2.4 2.5e-06 27.4 2.4 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DUF5010 PF16402.5 ORY99465.1 - 0.0034 16.3 0.4 0.0096 14.8 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5010) DUF494 PF04361.13 ORY99465.1 - 0.0047 16.8 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF494) tRNA-synt_1c PF00749.21 ORY99466.1 - 1.9e-106 355.5 0.0 2.9e-106 354.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ING PF12998.7 ORY99467.1 - 7.7e-22 77.8 0.6 1.3e-21 77.1 0.6 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY99467.1 - 1.7e-05 24.6 10.2 2.7e-05 24.0 10.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY99467.1 - 0.07 12.7 4.1 0.13 11.9 4.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 ORY99467.1 - 0.1 12.9 2.7 0.24 11.7 2.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C4pol PF14260.6 ORY99467.1 - 7.4 7.1 9.0 1.4 9.4 1.7 2.9 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta MDD_C PF18376.1 ORY99468.1 - 3.8e-70 235.4 0.3 8.5e-70 234.3 0.3 1.6 1 1 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 ORY99468.1 - 9.6e-08 32.2 1.8 1.9e-07 31.2 1.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Pkinase PF00069.25 ORY99469.1 - 1.1e-72 244.6 0.0 5.2e-72 242.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99469.1 - 3.1e-33 115.1 0.0 1.3e-31 109.8 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY99469.1 - 4.4e-06 26.2 1.2 0.028 13.8 0.5 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 ORY99469.1 - 8.2e-05 22.3 1.0 0.00013 21.6 1.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY99469.1 - 0.0051 15.8 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY99469.1 - 0.016 15.2 0.1 4.1 7.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY99469.1 - 0.017 13.9 0.0 0.04 12.7 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 ORY99469.1 - 0.094 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SecE PF00584.20 ORY99470.1 - 2.5e-14 52.9 0.0 3.1e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SQHop_cyclase_C PF13243.6 ORY99842.1 - 4.5e-53 180.4 1.1 3.4e-49 167.7 0.5 3.0 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY99842.1 - 2.7e-46 158.0 1.1 8.4e-41 140.0 0.0 3.4 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ORY99842.1 - 3.1e-32 110.0 3.2 2.4e-09 36.8 0.0 5.5 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ORY99842.1 - 1.2e-05 24.6 0.0 6.5e-05 22.1 0.0 2.2 3 0 0 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 ORY99842.1 - 0.0044 16.4 1.3 0.59 9.4 0.0 3.7 4 1 2 6 6 6 1 Pectic acid lyase Sld7_C PF18596.1 ORY99842.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Sld7 C-terminal domain YjeF_N PF03853.15 ORY99843.1 - 2.4e-28 99.2 0.0 3.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 ORY99843.1 - 2.2e-06 28.5 5.0 2.2e-06 28.5 5.0 2.3 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 ORY99843.1 - 0.0051 16.9 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 ORY99843.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF4614 PF15391.6 ORY99843.1 - 0.25 11.3 12.3 0.25 11.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF3043 PF11241.8 ORY99843.1 - 1.4 8.9 7.3 2.8 8.0 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Dynamin_N PF00350.23 ORY99844.1 - 1.6e-46 158.4 1.1 6.3e-45 153.2 0.0 2.8 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 ORY99844.1 - 7.3e-18 64.8 5.5 2.7e-16 59.6 0.1 3.2 4 0 0 4 4 4 2 Dynamin central region MMR_HSR1 PF01926.23 ORY99844.1 - 3.3e-06 27.2 0.0 1.9e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY99844.1 - 0.029 14.2 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NolV PF06635.12 ORY99844.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein NolV AAA_15 PF13175.6 ORY99844.1 - 0.088 12.5 3.0 0.12 12.1 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 ORY99844.1 - 0.61 10.4 0.0 0.61 10.4 0.0 2.5 4 1 0 4 4 4 0 AAA ATPase domain CHCH PF06747.13 ORY99845.1 - 2.6e-09 37.0 9.0 3.8e-09 36.4 9.0 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 ORY99845.1 - 0.0012 18.8 6.0 0.0018 18.3 6.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 ORY99845.1 - 0.0032 17.7 8.1 0.0099 16.2 8.1 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 ORY99845.1 - 0.0033 17.1 3.3 0.0043 16.7 3.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 ORY99845.1 - 0.0093 16.0 8.6 0.017 15.2 8.5 1.5 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 ORY99845.1 - 0.032 14.6 7.4 0.25 11.7 3.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 ORY99845.1 - 0.068 13.6 5.1 0.21 12.0 5.2 1.7 1 1 0 1 1 1 0 GCK domain UPF0203 PF05254.12 ORY99845.1 - 0.44 10.8 7.5 2 8.7 1.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) adh_short PF00106.25 ORY99846.1 - 6.6e-43 146.4 0.0 8.5e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY99846.1 - 1.4e-25 90.3 0.0 1.8e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY99846.1 - 1.3e-14 54.5 0.1 2e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY99846.1 - 1.4e-05 25.0 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY99846.1 - 0.00023 20.7 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY99846.1 - 0.00033 20.2 0.1 0.00052 19.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY99846.1 - 0.00045 19.3 0.4 0.00073 18.6 0.4 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 ORY99846.1 - 0.0013 18.1 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 ORY99846.1 - 0.019 14.1 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORY99846.1 - 0.032 14.5 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 ORY99846.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ORY99846.1 - 0.051 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 ORY99846.1 - 0.052 13.4 0.3 0.095 12.5 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.15 ORY99846.1 - 0.06 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.25 ORY99847.1 - 6.6e-70 235.5 0.0 1.1e-69 234.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99847.1 - 4.2e-40 137.7 0.0 7.7e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY99847.1 - 5.4e-06 25.9 0.0 5.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY99847.1 - 0.0001 21.2 0.0 0.0002 20.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORY99847.1 - 0.025 13.6 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 ORY99847.1 - 0.067 12.8 0.3 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH PF00169.29 ORY99848.1 - 2.1e-21 76.4 1.4 4.5e-21 75.3 1.4 1.5 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 ORY99848.1 - 3.3e-16 59.1 0.1 8.1e-16 57.9 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 ORY99848.1 - 4e-14 52.2 0.0 9e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 ORY99848.1 - 2.1e-13 50.5 1.3 5.9e-13 49.0 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 ORY99848.1 - 2.2e-13 49.6 1.0 4.3e-13 48.6 0.2 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ORY99848.1 - 8.1e-12 44.7 0.1 1.7e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.31 ORY99848.1 - 4.2e-07 30.1 0.0 8.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_11 PF15413.6 ORY99848.1 - 1.2e-06 28.9 11.0 2.3e-06 28.0 5.5 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 ORY99848.1 - 0.001 19.3 0.6 0.003 17.8 0.6 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 ORY99848.1 - 0.031 14.4 0.4 0.081 13.0 0.4 1.7 1 0 0 1 1 1 0 PH domain SAM_PNT PF02198.16 ORY99848.1 - 0.035 14.1 0.2 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_KSR1 PF13543.6 ORY99848.1 - 0.053 13.7 0.3 0.2 11.8 0.2 2.0 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Aldo_ket_red PF00248.21 ORY99849.1 - 3.4e-76 256.3 0.0 3.9e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RhoGAP PF00620.27 ORY99851.1 - 2.9e-35 121.3 0.0 4.2e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Macoilin PF09726.9 ORY99851.1 - 0.046 12.3 7.0 0.055 12.0 7.0 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 ORY99851.1 - 0.25 10.0 1.3 0.31 9.7 1.3 1.1 1 0 0 1 1 1 0 Presenilin MMU163 PF17119.5 ORY99851.1 - 0.38 9.9 3.5 0.59 9.3 3.5 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF1180 PF06679.12 ORY99851.1 - 5.6 7.4 8.5 9.8 6.6 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RRM_1 PF00076.22 ORY99852.1 - 1.2e-17 63.5 0.0 1.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 ORY99853.1 - 1.3e-08 34.6 0.5 2.9e-08 33.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY99853.1 - 2.4e-08 33.7 2.3 3.3e-08 33.2 0.2 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 ORY99853.1 - 6.6 7.3 10.2 20 5.8 0.0 5.6 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 ORY99855.1 - 0.0061 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGAP PF00616.19 ORY99856.1 - 5.6e-60 202.6 0.1 1.3e-59 201.4 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORY99856.1 - 3e-39 134.3 0.5 1.1e-38 132.5 0.0 2.3 2 0 0 2 2 2 1 RasGAP C-terminus YabA PF06156.13 ORY99856.1 - 0.0029 18.2 2.9 1.6 9.4 0.2 3.3 2 0 0 2 2 2 2 Initiation control protein YabA DUF4047 PF13256.6 ORY99856.1 - 0.093 12.9 0.3 0.32 11.2 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) TPR_MLP1_2 PF07926.12 ORY99856.1 - 0.23 11.5 7.8 1.5 8.9 1.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CASP_C PF08172.12 ORY99856.1 - 2 7.7 9.6 2.2 7.6 0.8 2.8 3 0 0 3 3 3 0 CASP C terminal NIF PF03031.18 ORY99857.1 - 6e-53 178.8 0.2 7.9e-53 178.4 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORY99857.1 - 0.0064 16.9 0.1 0.096 13.1 0.0 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Replicase PF03090.17 ORY99857.1 - 0.13 12.1 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 Replicase family ELMO_CED12 PF04727.13 ORY99858.1 - 1.3e-33 116.5 1.1 2.8e-33 115.5 1.1 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family GATA PF00320.27 ORY99859.1 - 9.6e-30 101.9 16.2 1.1e-15 56.9 4.5 2.3 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY99859.1 - 0.00029 20.3 6.0 0.13 11.7 0.5 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY99859.1 - 0.00034 20.7 1.2 0.79 9.9 0.1 2.4 2 0 0 2 2 2 2 Zinc ribbon domain DUF2387 PF09526.10 ORY99859.1 - 0.00091 19.3 3.3 0.13 12.4 0.1 2.6 2 1 1 3 3 3 2 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.17 ORY99859.1 - 0.034 14.0 5.3 2.4 8.1 0.7 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 ORY99859.1 - 0.036 14.2 5.0 1.9 8.7 0.4 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 ORY99859.1 - 0.039 14.0 6.7 0.66 10.0 7.5 2.5 1 1 2 3 3 3 0 Double zinc ribbon zf-B_box PF00643.24 ORY99859.1 - 0.042 14.0 7.2 23 5.3 0.0 4.1 4 0 0 4 4 4 0 B-box zinc finger FYVE PF01363.21 ORY99859.1 - 0.056 13.6 3.2 1.2 9.3 0.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger ZF-HD_dimer PF04770.12 ORY99859.1 - 0.89 9.9 7.8 4.1 7.8 0.8 3.4 3 1 0 3 3 3 0 ZF-HD protein dimerisation region Vps36-NZF-N PF16988.5 ORY99859.1 - 0.91 9.0 7.0 3.9 6.9 0.6 3.1 2 2 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pex14_N PF04695.13 ORY99859.1 - 1.6 9.4 12.2 3.4 8.3 12.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zinc_ribbon_15 PF17032.5 ORY99859.1 - 2.3 9.0 5.6 19 6.1 3.1 2.8 1 1 2 3 3 3 0 zinc-ribbon family FAM163 PF15069.6 ORY99859.1 - 4.1 7.8 6.5 1.1 9.7 0.5 2.6 2 1 1 3 3 3 0 FAM163 family DUF1752 PF08550.10 ORY99860.1 - 3.5e-12 45.9 2.2 6.6e-12 45.0 2.2 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF4638 PF15472.6 ORY99860.1 - 7.1 6.3 17.0 6.1 6.5 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Sec1 PF00995.23 ORY99861.1 - 2.2e-118 397.0 0.0 2.7e-118 396.7 0.0 1.1 1 0 0 1 1 1 1 Sec1 family HAD_2 PF13419.6 ORY99861.1 - 0.16 12.0 0.3 0.4 10.7 0.1 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Det1 PF09737.9 ORY99862.1 - 1.1e-09 37.9 0.3 1.7e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 Macoilin PF09726.9 ORY99863.1 - 3.7 6.0 6.3 5 5.6 6.3 1.2 1 0 0 1 1 1 0 Macoilin family Hydin_ADK PF17213.3 ORY99863.1 - 5.7 7.2 7.1 0.7 10.1 2.7 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain PAT1 PF09770.9 ORY99863.1 - 9.1 4.4 14.2 12 4.0 14.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TAF4 PF05236.14 ORY99864.1 - 3.7e-38 131.9 4.1 3.7e-38 131.9 4.1 2.0 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 ORY99864.1 - 0.11 12.2 2.6 0.73 9.5 0.0 2.9 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1115 PF06544.12 ORY99865.1 - 5.4e-10 39.5 0.0 1.1e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Lsr2 PF11774.8 ORY99865.1 - 0.023 14.8 0.5 0.045 13.9 0.5 1.5 1 0 0 1 1 1 0 Lsr2 DUF3486 PF11985.8 ORY99865.1 - 0.032 14.7 0.5 0.045 14.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Alfin PF12165.8 ORY99865.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Alfin LSM PF01423.22 ORY99866.1 - 4.6e-21 74.3 0.8 5.1e-21 74.1 0.8 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY99866.1 - 2.6e-05 24.3 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ORY99866.1 - 0.0073 16.4 0.1 0.0077 16.3 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain UPF0176_N PF17773.1 ORY99868.1 - 4.7e-16 58.9 0.0 9.1e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 ORY99868.1 - 6.6e-15 55.2 8.3 2.3e-14 53.5 8.3 2.0 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 ORY99868.1 - 8.8e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Flavodoxin_5 PF12724.7 ORY99868.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain bZIP_2 PF07716.15 ORY99869.1 - 2.4e-11 43.5 15.6 2.4e-11 43.5 15.6 1.9 2 0 0 2 2 2 1 Basic region leucine zipper XhlA PF10779.9 ORY99869.1 - 0.00051 20.2 2.7 0.0011 19.1 2.7 1.6 1 0 0 1 1 1 1 Haemolysin XhlA SR-25 PF10500.9 ORY99869.1 - 0.0017 18.0 12.7 0.0017 18.0 12.7 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein bZIP_1 PF00170.21 ORY99869.1 - 0.0035 17.4 11.9 0.0035 17.4 11.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor TFIIA PF03153.13 ORY99869.1 - 0.0097 15.9 21.7 0.013 15.5 21.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NAM-associated PF14303.6 ORY99869.1 - 1.2 9.8 20.1 0.45 11.2 14.3 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Peptidase_S64 PF08192.11 ORY99869.1 - 1.5 7.2 14.4 1.9 6.9 14.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 Nucleo_P87 PF07267.11 ORY99869.1 - 2.9 6.6 14.2 3.3 6.4 14.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spore_coat_CotO PF14153.6 ORY99870.1 - 0.022 14.7 5.5 0.025 14.5 5.5 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF4228 PF14009.6 ORY99870.1 - 0.046 14.1 2.2 0.059 13.7 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF3381 PF11861.8 ORY99870.1 - 0.2 11.4 12.1 0.24 11.2 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) MEF2_binding PF09047.10 ORY99870.1 - 0.9 9.4 4.9 8.8 6.3 0.4 2.6 2 0 0 2 2 2 0 MEF2 binding Presenilin PF01080.17 ORY99870.1 - 1.1 8.0 4.3 1.1 8.0 4.3 1.0 1 0 0 1 1 1 0 Presenilin Kelch_6 PF13964.6 ORY99871.1 - 6.2e-12 45.3 5.5 1.8e-05 24.8 0.2 4.4 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 ORY99871.1 - 1.5e-10 40.8 0.6 0.00022 21.1 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 ORY99871.1 - 1e-08 35.2 3.0 0.0065 16.7 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY99871.1 - 5.3e-08 32.3 0.9 0.0032 17.0 0.2 4.2 3 2 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 ORY99871.1 - 4e-05 23.5 4.0 0.0002 21.3 0.0 3.3 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY99871.1 - 0.0014 18.5 3.8 0.2 11.7 0.1 4.0 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 ORY99872.1 - 0.0046 16.9 0.4 0.5 10.4 0.0 2.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY99872.1 - 0.013 15.8 1.6 0.19 12.0 0.2 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY99872.1 - 0.14 12.5 0.0 0.93 9.9 0.0 2.1 2 0 0 2 2 2 0 Kelch motif PHD PF00628.29 ORY99874.1 - 9.2e-06 25.5 9.6 9.2e-06 25.5 9.6 2.0 2 0 0 2 2 2 1 PHD-finger GATA PF00320.27 ORY99874.1 - 9.2e-05 22.0 5.6 0.00027 20.5 5.6 1.8 1 0 0 1 1 1 1 GATA zinc finger PHD_2 PF13831.6 ORY99874.1 - 0.0048 16.4 3.7 0.013 15.0 3.7 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 ORY99874.1 - 0.0059 16.5 3.2 0.0059 16.5 3.2 2.6 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 ORY99874.1 - 0.049 13.3 4.8 0.12 12.0 4.8 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF4611 PF15387.6 ORY99874.1 - 0.13 12.5 4.7 0.24 11.6 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Zf_RING PF16744.5 ORY99874.1 - 3.1 8.0 7.9 0.29 11.3 2.8 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger Kinesin PF00225.23 ORY99875.1 - 2.5e-101 339.0 0.0 2.5e-101 339.0 0.0 2.5 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY99875.1 - 2.2e-20 73.1 1.3 6.4e-20 71.6 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding DUF1192 PF06698.11 ORY99875.1 - 0.056 13.5 0.3 0.056 13.5 0.3 5.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) DUF2431 PF10354.9 ORY99876.1 - 2.5e-48 164.5 0.0 3.5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Radial_spoke PF04712.12 ORY99876.1 - 7.5e-05 21.9 0.9 7.5e-05 21.9 0.9 2.1 2 0 0 2 2 2 1 Radial spokehead-like protein TFCD_C PF12612.8 ORY99877.1 - 1.5e-50 171.7 0.0 1.6e-49 168.3 0.0 2.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 ORY99877.1 - 6.8e-06 26.4 4.9 0.14 12.6 0.0 6.4 6 1 1 7 7 7 1 HEAT repeats HEAT PF02985.22 ORY99877.1 - 0.0069 16.5 8.4 0.037 14.3 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY99877.1 - 0.016 15.8 0.2 2.6 8.7 0.0 4.1 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 ORY99877.1 - 0.03 14.5 0.0 0.31 11.2 0.0 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 ORY99877.1 - 0.68 10.8 3.1 20 6.2 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 ORY99877.1 - 5.2 7.7 8.8 19 5.9 0.0 6.0 7 1 1 8 8 8 0 HEAT-like repeat Ank_2 PF12796.7 ORY99878.1 - 1.3e-26 93.0 2.3 3.4e-13 50.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY99878.1 - 1.3e-23 83.1 4.8 4.5e-08 33.5 0.5 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY99878.1 - 2.7e-17 62.4 6.1 0.0011 19.3 0.2 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 ORY99878.1 - 8.7e-17 59.5 2.6 0.0038 17.6 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ORY99878.1 - 8e-15 54.7 8.2 6.7e-05 23.1 0.1 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) WD40 PF00400.32 ORY99880.1 - 7.6e-44 146.8 18.9 8e-07 29.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY99880.1 - 1.1e-14 54.5 0.0 0.0032 17.7 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY99880.1 - 0.00034 20.5 0.0 0.33 10.8 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY99880.1 - 0.0012 18.2 0.0 6.7 5.9 0.0 3.8 1 1 3 4 4 4 2 WD40-like domain FAINT PF04385.15 ORY99880.1 - 0.068 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Nup160 PF11715.8 ORY99880.1 - 0.25 10.0 0.8 4.4 5.8 0.1 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PINIT PF14324.6 ORY99881.1 - 6.9e-26 91.3 0.1 1.3e-25 90.5 0.1 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 ORY99881.1 - 2e-22 78.6 8.1 3.4e-22 77.9 8.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY99881.1 - 3e-10 39.8 4.3 6.1e-10 38.8 4.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 ORY99881.1 - 0.024 14.4 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 SAP domain zf-C3HC4_2 PF13923.6 ORY99881.1 - 0.7 9.8 8.3 2.2 8.2 8.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PK PF00224.21 ORY99882.1 - 7.2e-163 541.4 1.8 8.9e-163 541.1 1.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORY99882.1 - 2.3e-36 124.6 0.0 5.4e-36 123.4 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORY99882.1 - 0.0002 20.5 0.1 0.00045 19.4 0.1 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family zf-C2H2 PF00096.26 ORY99883.1 - 2.7e-07 30.7 17.2 2.9e-05 24.3 3.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY99883.1 - 6.5e-06 26.5 14.3 0.00023 21.7 2.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY99883.1 - 0.00071 19.3 3.3 0.00071 19.3 3.3 3.0 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 ORY99883.1 - 0.0014 18.9 8.3 0.002 18.4 8.3 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF4764 PF15961.5 ORY99883.1 - 0.0024 16.7 0.6 0.0024 16.7 0.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4764) zf-H2C2_2 PF13465.6 ORY99883.1 - 0.0044 17.4 18.7 0.018 15.5 1.5 3.3 2 1 1 3 3 3 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 ORY99883.1 - 0.021 14.8 3.7 0.035 14.1 3.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 ORY99883.1 - 0.024 15.1 6.6 0.04 14.4 6.6 1.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORY99883.1 - 0.033 14.5 1.7 0.033 14.5 1.7 2.4 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CAV_VP3 PF04771.12 ORY99883.1 - 0.046 13.9 0.2 0.065 13.4 0.2 1.4 1 1 0 1 1 1 0 Chicken anaemia virus VP-3 protein Elf1 PF05129.13 ORY99883.1 - 0.056 13.5 8.8 0.16 12.0 1.0 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.7 ORY99883.1 - 0.15 12.4 10.0 0.88 9.9 2.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CobU PF02283.16 ORY99883.1 - 2 8.0 4.5 0.57 9.7 0.9 1.7 1 1 1 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TauD PF02668.16 ORY99884.1 - 2.7e-48 165.1 1.6 4e-48 164.5 1.6 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORY99884.1 - 1.5e-10 41.6 1.2 5e-10 39.9 0.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORY99884.1 - 4.6e-05 22.7 0.1 7.3e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 CsiD Methyltransf_23 PF13489.6 ORY99885.1 - 5.9e-10 39.2 0.0 7.1e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY99885.1 - 9e-09 36.0 0.0 1.5e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY99885.1 - 9.7e-07 29.4 0.0 2.9e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY99885.1 - 8.3e-06 26.4 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY99885.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2012 PF09430.10 ORY99886.1 - 4.1e-27 94.7 0.0 6.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) PepSY_TM PF03929.16 ORY99886.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region CarboxypepD_reg PF13620.6 ORY99886.1 - 0.03 14.6 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Dpy-30 PF05186.13 ORY99887.1 - 2.9e-12 46.1 0.1 4.3e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ndc1_Nup PF09531.10 ORY99887.1 - 4.5 5.8 11.7 5.2 5.6 11.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RVT_3 PF13456.6 ORY99888.1 - 0.12 12.2 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like HIT PF01230.23 ORY99889.1 - 1.1e-22 80.6 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORY99889.1 - 8.9e-08 32.6 0.0 1.4e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ADH_N_2 PF16884.5 ORY99890.1 - 0.04 13.8 0.0 0.099 12.6 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase TUSC2 PF15000.6 ORY99890.1 - 0.079 13.2 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Tumour suppressor candidate 2 His_biosynth PF00977.21 ORY99891.1 - 1.8e-38 132.3 0.0 2.1e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 ORY99891.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase GATA PF00320.27 ORY99893.1 - 0.00012 21.6 2.9 0.00012 21.6 2.9 2.7 3 0 0 3 3 3 1 GATA zinc finger Acyl-CoA_dh_1 PF00441.24 ORY99895.1 - 2e-42 145.0 0.1 3.6e-42 144.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY99895.1 - 2.2e-37 128.2 0.0 4.1e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY99895.1 - 1.7e-26 92.3 0.0 2.8e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY99895.1 - 1.2e-13 51.4 0.1 2.9e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ost5 PF05251.12 ORY99897.1 - 5.2e-17 61.9 8.4 5.8e-17 61.7 8.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 TOM13 PF08219.11 ORY99898.1 - 5e-21 74.5 0.2 7.6e-21 73.9 0.2 1.3 1 0 0 1 1 1 1 Outer membrane protein TOM13 RNA_pol_Rpb4 PF03874.16 ORY99899.1 - 8.9e-22 77.7 1.5 1.1e-21 77.4 1.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1170 PF06663.13 ORY99899.1 - 0.086 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) Acyl-CoA_dh_1 PF00441.24 ORY99900.1 - 1.1e-39 136.0 1.5 1.6e-39 135.5 1.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY99900.1 - 4.3e-23 81.3 0.0 1e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY99900.1 - 1.4e-22 79.6 0.1 3e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY99900.1 - 3.5e-19 69.5 0.0 9.9e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY99900.1 - 9.4e-08 32.4 0.1 1.8e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Gly_transf_sug PF04488.15 ORY99901.1 - 7.5e-09 36.1 0.0 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY99901.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Laminin_G_3 PF13385.6 ORY99901.1 - 0.0003 21.0 0.1 0.00075 19.7 0.1 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Caps_synth PF05704.12 ORY99901.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein SNF5 PF04855.12 ORY99902.1 - 9.8e-67 225.2 1.3 9.8e-67 225.2 1.3 2.7 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 XLF PF09302.11 ORY99902.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.0 3 1 1 4 4 4 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF2812 PF11193.8 ORY99903.1 - 0.82 9.9 4.8 0.2 11.9 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2812) SPT_ssu-like PF11779.8 ORY99904.1 - 1e-14 53.9 3.1 1.2e-14 53.6 3.1 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like WD40 PF00400.32 ORY99905.1 - 1.7e-59 196.4 15.0 7.5e-10 39.2 0.1 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY99905.1 - 2.3e-15 56.6 0.9 3e-06 27.4 0.0 5.9 2 2 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY99905.1 - 1.1e-12 47.4 5.7 0.012 14.3 0.7 6.2 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY99905.1 - 2.7e-08 33.0 1.5 0.083 11.6 0.1 4.0 2 1 2 4 4 4 3 Nup133 N terminal like Ge1_WD40 PF16529.5 ORY99905.1 - 0.0037 16.3 3.6 0.99 8.3 0.1 3.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AATF-Che1 PF13339.6 ORY99906.1 - 7.8 7.2 13.6 60 4.3 13.3 2.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Ribosomal_S13 PF00416.22 ORY99907.1 - 4.6e-21 75.5 1.0 5.6e-19 68.8 1.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORY99907.1 - 0.0097 14.7 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) BicD PF09730.9 ORY99907.1 - 0.047 12.1 0.0 0.052 12.0 0.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D WBS_methylT PF12589.8 ORY99908.1 - 3.9e-20 72.4 6.5 5.7e-20 71.9 6.5 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 ORY99908.1 - 2e-12 47.6 0.0 3.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY99908.1 - 1.7e-10 41.5 0.0 3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY99908.1 - 2.9e-08 34.4 0.0 7e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY99908.1 - 5.1e-06 26.4 0.0 6.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY99908.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 ORY99908.1 - 0.0045 17.3 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 ORY99908.1 - 0.033 13.6 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 ORY99908.1 - 0.044 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 ORY99908.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Chitin_synth_2 PF03142.15 ORY99909.1 - 8.7e-239 793.5 2.4 1.2e-238 793.1 2.4 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY99909.1 - 4e-146 488.0 0.1 7.1e-146 487.2 0.1 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 ORY99909.1 - 1.5e-17 63.5 0.4 3.5e-14 52.7 0.1 3.5 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ORY99909.1 - 1.3e-12 48.0 0.6 5.6e-12 46.0 0.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY99909.1 - 2e-12 47.5 0.0 2.3e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY99909.1 - 0.0001 22.1 0.0 0.016 15.1 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF87 PF01935.17 ORY99909.1 - 0.0044 17.1 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain Glyco_transf_21 PF13506.6 ORY99909.1 - 0.0084 15.6 0.0 0.032 13.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sigma54_activat PF00158.26 ORY99909.1 - 0.028 14.1 0.1 0.078 12.7 0.1 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 ORY99909.1 - 0.07 13.5 0.0 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORY99909.1 - 0.084 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY99909.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ala_racemase_N PF01168.20 ORY99910.1 - 1e-19 71.1 0.0 1.2e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Dna2 PF08696.11 ORY99917.1 - 7.6e-59 198.9 0.1 1.6e-58 197.8 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 ORY99917.1 - 2.9e-11 43.7 0.1 1e-10 41.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY99917.1 - 7.2e-09 35.6 0.2 1.2e-08 34.9 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY99917.1 - 9.3e-07 29.3 0.2 2.1e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 ORY99917.1 - 1.1e-05 25.7 0.0 0.00019 21.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 ORY99917.1 - 0.00022 21.3 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily SRP54 PF00448.22 ORY99917.1 - 0.00022 20.9 0.1 0.00035 20.2 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 ORY99917.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 ORY99917.1 - 0.00078 19.3 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 Helicase ATPase PF06745.13 ORY99917.1 - 0.0031 16.9 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 KaiC UvrD-helicase PF00580.21 ORY99917.1 - 0.0033 17.0 0.2 0.016 14.7 0.1 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 ORY99917.1 - 0.0041 17.1 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY99917.1 - 0.0044 17.4 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY99917.1 - 0.011 16.0 0.1 0.059 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY99917.1 - 0.026 14.9 0.0 0.072 13.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 ORY99917.1 - 0.034 14.2 0.5 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain ResIII PF04851.15 ORY99917.1 - 0.038 14.0 0.5 0.074 13.0 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 ORY99917.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY99917.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ORY99917.1 - 0.095 12.1 0.1 0.43 10.0 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein MeaB PF03308.16 ORY99917.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 ORY99917.1 - 0.13 12.3 0.7 0.39 10.8 0.7 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.21 ORY99917.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 ORY99917.1 - 0.16 11.1 0.3 1 8.4 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_18 PF13238.6 ORY99917.1 - 0.18 12.4 0.1 0.46 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 ORY99917.1 - 0.19 11.6 0.6 0.82 9.6 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Hira PF07569.11 ORY99918.1 - 2.9e-55 187.4 0.1 9.3e-55 185.8 0.1 1.9 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 ORY99918.1 - 9.3e-27 92.8 16.5 2.2e-07 31.4 1.7 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY99918.1 - 8.1e-15 54.9 1.7 0.1 12.9 0.0 7.1 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 ORY99918.1 - 5.3e-07 29.3 2.8 1.6e-06 27.8 2.3 2.1 2 0 0 2 2 2 1 HIRA B motif Ge1_WD40 PF16529.5 ORY99918.1 - 0.012 14.6 0.1 9.1 5.1 0.0 3.7 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ORY99918.1 - 0.043 13.8 2.9 12 6.0 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 ORY99918.1 - 2.4 8.1 8.0 6 6.8 0.0 3.7 2 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term PRKCSH PF07915.13 ORY99919.1 - 1.6e-11 45.0 0.8 1.6e-11 45.0 0.8 3.0 4 0 0 4 4 4 1 Glucosidase II beta subunit-like protein WD40 PF00400.32 ORY99920.1 - 9.2e-08 32.6 1.5 0.00092 20.0 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY99920.1 - 0.00013 22.2 0.0 0.68 10.3 0.0 4.4 2 2 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY99920.1 - 0.12 11.0 0.0 0.44 9.1 0.0 1.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 p450 PF00067.22 ORY99921.1 - 5.2e-73 246.3 0.0 6.4e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 ORY99922.1 - 1.4e-09 38.1 0.0 2.8e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY99922.1 - 2.6e-07 30.5 0.0 3.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family SET PF00856.28 ORY99923.1 - 5.5e-14 52.9 0.0 1.2e-13 51.9 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-FLZ PF04570.14 ORY99923.1 - 0.48 9.9 4.5 1.3 8.5 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 FMO-like PF00743.19 ORY99924.1 - 5.2e-45 153.9 0.5 2.9e-24 85.4 0.1 3.7 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY99924.1 - 1.3e-22 80.5 0.4 6.9e-11 41.9 0.2 4.1 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY99924.1 - 3e-16 59.5 0.0 1.5e-15 57.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY99924.1 - 5.6e-12 45.5 0.4 9.2e-09 34.9 0.2 3.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY99924.1 - 1e-07 32.1 0.1 4.4e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY99924.1 - 4.1e-06 26.9 1.3 0.0009 19.3 0.0 3.3 4 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 ORY99924.1 - 7.5e-06 25.8 1.2 0.00076 19.2 0.0 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORY99924.1 - 3.5e-05 23.3 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ORY99924.1 - 3.9e-05 24.1 0.5 0.15 12.6 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.24 ORY99924.1 - 5.9e-05 23.5 0.0 0.3 11.5 0.0 3.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.12 ORY99924.1 - 0.00023 20.8 0.0 0.71 9.4 0.0 2.4 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 ORY99924.1 - 0.00029 20.2 1.6 0.00049 19.4 0.0 2.1 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 ORY99924.1 - 0.00053 19.2 0.1 0.0014 17.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ORY99924.1 - 0.0016 17.9 0.0 0.0039 16.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY99924.1 - 0.0043 15.8 0.1 0.015 14.0 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 ORY99924.1 - 0.0048 17.0 0.0 0.43 10.6 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ORY99924.1 - 0.01 15.1 0.2 0.026 13.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 ORY99924.1 - 0.026 15.0 2.0 2.9 8.4 0.0 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding DJ-1_PfpI PF01965.24 ORY99924.1 - 0.043 13.6 0.0 0.79 9.5 0.0 2.6 2 1 0 2 2 2 0 DJ-1/PfpI family ApbA PF02558.16 ORY99924.1 - 0.046 13.4 0.4 6.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 ORY99924.1 - 0.11 12.0 0.2 0.56 9.7 0.0 2.2 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Acyl-CoA_dh_1 PF00441.24 ORY99925.1 - 3.6e-31 108.4 2.5 3.7e-31 108.3 1.5 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY99925.1 - 1.8e-22 79.2 0.0 4.4e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY99925.1 - 1.1e-17 64.0 0.1 2.1e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY99925.1 - 5e-12 46.5 0.0 1.5e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY99925.1 - 4.5e-06 27.0 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyltransferase PF01553.21 ORY99926.1 - 1.9e-09 37.3 0.0 0.0022 17.6 0.0 2.6 3 0 0 3 3 3 2 Acyltransferase Cpn10 PF00166.21 ORY99926.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit Ribosomal_L7Ae PF01248.26 ORY99927.1 - 3.3e-25 87.6 0.1 5.3e-25 87.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 ORY99927.1 - 0.099 12.9 1.4 11 6.3 0.0 2.7 2 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Peptidase_S29 PF02907.15 ORY99927.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease zf-MYND PF01753.18 ORY99928.1 - 9.7e-07 28.8 17.8 9.7e-07 28.8 17.8 2.1 2 0 0 2 2 2 1 MYND finger Aida_N PF08910.10 ORY99928.1 - 0.26 11.7 3.3 0.47 10.9 0.2 2.4 2 0 0 2 2 2 0 Aida N-terminus NifU_N PF01592.16 ORY99929.1 - 2.8e-54 182.7 0.1 3.3e-54 182.5 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.29 ORY99930.1 - 2.1e-14 53.6 0.0 1.5e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY99930.1 - 4.1e-06 26.6 0.0 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Amino_oxidase PF01593.24 ORY99931.1 - 3.8e-71 240.7 0.1 1.9e-70 238.4 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY99931.1 - 3.9e-09 36.6 0.1 8.4e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY99931.1 - 2.8e-07 30.1 1.5 0.0075 15.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY99931.1 - 4.4e-06 26.5 0.9 5.2e-05 23.0 0.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY99931.1 - 3.9e-05 23.1 4.1 0.041 13.1 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY99931.1 - 9.6e-05 22.9 2.4 0.048 14.2 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY99931.1 - 0.0013 18.0 0.3 0.0096 15.2 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ORY99931.1 - 0.0015 18.0 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY99931.1 - 0.02 14.9 0.7 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ORY99931.1 - 0.025 13.9 0.6 0.025 13.9 0.6 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY99931.1 - 0.11 11.2 6.7 3.8 6.1 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 ORY99931.1 - 0.15 11.2 0.3 0.28 10.4 0.3 1.3 1 0 0 1 1 1 0 Thi4 family SNARE_assoc PF09335.11 ORY99932.1 - 3e-17 63.2 7.6 3e-17 63.2 7.6 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Vasculin PF15337.6 ORY99932.1 - 0.041 14.7 0.4 0.084 13.7 0.4 1.5 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 SH3_9 PF14604.6 ORY99933.1 - 3.6e-12 45.9 0.1 5e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY99933.1 - 3.4e-07 29.8 0.0 4.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY99933.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain DPBB_1 PF03330.18 ORY99934.1 - 7.3e-12 45.4 0.1 8.4e-12 45.2 0.1 1.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY99934.1 - 0.00037 20.3 0.1 0.0005 19.9 0.1 1.3 1 1 0 1 1 1 1 Barwin family Glyco_transf_15 PF01793.16 ORY99935.1 - 5.4e-116 387.4 7.9 6.6e-116 387.1 7.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Phage_Mu_Gam PF07352.12 ORY99936.1 - 0.014 15.3 2.4 0.047 13.6 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein betaPIX_CC PF16523.5 ORY99936.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 betaPIX coiled coil UPF0449 PF15136.6 ORY99936.1 - 0.27 11.7 4.5 1.8 9.1 0.6 3.3 2 2 1 3 3 3 0 Uncharacterised protein family UPF0449 TPR_MLP1_2 PF07926.12 ORY99936.1 - 1.1 9.3 7.7 1.2 9.2 0.5 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 ORY99936.1 - 2.6 8.1 4.6 31 4.6 0.2 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 ORY99936.1 - 7.1 6.5 6.5 0.94 9.3 0.5 2.4 3 0 0 3 3 3 0 Septum formation initiator GTP_EFTU PF00009.27 ORY99937.1 - 3e-59 199.8 0.1 6.6e-59 198.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORY99937.1 - 2.4e-14 53.1 0.0 6.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ORY99937.1 - 2.2e-09 37.3 0.0 5.2e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ORY99937.1 - 5.8e-06 26.6 0.0 1.6e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY99937.1 - 0.029 14.4 0.0 0.083 13.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Aminotran_3 PF00202.21 ORY99938.1 - 2.6e-122 408.4 0.0 3.5e-122 408.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY99938.1 - 0.0002 20.7 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Use1 PF09753.9 ORY99939.1 - 2.8e-28 99.3 1.8 3.7e-28 98.9 1.8 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 ORY99939.1 - 0.0074 14.3 1.0 0.022 12.7 1.0 1.6 1 1 0 1 1 1 1 Prominin Orai-1 PF07856.12 ORY99939.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity Spore_III_AB PF09548.10 ORY99939.1 - 0.037 14.1 0.3 0.35 10.9 0.0 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4407 PF14362.6 ORY99939.1 - 0.62 9.4 3.7 0.93 8.8 3.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 ORY99939.1 - 1.7 8.6 5.9 3.3 7.7 5.9 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hpt PF01627.23 ORY99940.1 - 4.5e-13 49.3 0.3 8.6e-13 48.4 0.0 1.6 2 0 0 2 2 2 1 Hpt domain DUF4484 PF14831.6 ORY99940.1 - 0.03 14.4 4.9 0.025 14.6 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Sec2p PF06428.11 ORY99941.1 - 6e-06 26.1 6.8 2.5e-05 24.2 6.8 2.1 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Rpr2 PF04032.16 ORY99941.1 - 0.12 12.6 4.6 5.6 7.3 0.6 3.3 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HBM PF16591.5 ORY99941.1 - 0.54 9.6 7.5 0.1 12.0 2.1 2.2 2 0 0 2 2 2 0 Helical bimodular sensor domain PCRF PF03462.18 ORY99941.1 - 2.2 8.1 5.7 0.86 9.4 2.1 2.1 2 1 0 2 2 2 0 PCRF domain Caudo_TAP PF02413.17 ORY99941.1 - 2.3 8.4 8.2 4.9 7.3 0.6 3.6 3 1 1 4 4 4 0 Caudovirales tail fibre assembly protein, lambda gpK DUF2203 PF09969.9 ORY99941.1 - 3.2 8.5 8.3 5.8 7.6 3.8 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cep57_CLD_2 PF14197.6 ORY99941.1 - 4 7.6 9.6 4 7.6 4.8 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 FlgN PF05130.12 ORY99941.1 - 4.5 7.8 9.9 8.8 6.8 8.2 2.2 2 0 0 2 2 2 0 FlgN protein CHDCT2 PF08074.11 ORY99941.1 - 9 6.4 8.2 0.73 10.0 2.3 2.2 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain FSA_C PF10479.9 ORY99941.1 - 9.7 4.2 8.2 0.99 7.5 0.7 2.0 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus GPI-anchored PF10342.9 ORY99942.1 - 9.8e-20 71.1 1.6 9.8e-20 71.1 1.6 1.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 ORY99942.1 - 0.026 14.3 0.3 0.034 13.9 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) SPX PF03105.19 ORY99942.1 - 3.8 7.3 8.3 4.3 7.2 8.3 1.1 1 0 0 1 1 1 0 SPX domain PC4 PF02229.16 ORY99945.1 - 1.5e-17 62.9 0.0 4.3e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Aminotran_1_2 PF00155.21 ORY99946.1 - 2e-63 214.8 0.0 2.4e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY99946.1 - 0.073 11.6 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme EBP PF05241.12 ORY99947.1 - 4.5e-44 150.0 7.4 5.5e-44 149.7 7.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein FtsK_4TM PF13491.6 ORY99947.1 - 0.051 13.3 4.1 3.4 7.3 0.3 2.3 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF4282 PF14110.6 ORY99947.1 - 2.3 9.0 5.1 23 5.8 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) Ribosomal_L28e PF01778.17 ORY99948.1 - 2.8e-42 144.1 1.9 2.8e-42 144.1 1.9 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 ORY99948.1 - 3e-28 98.3 21.7 3e-28 98.3 21.7 2.0 3 0 0 3 3 3 1 Mak16 protein C-terminal region PYC_OADA PF02436.18 ORY99948.1 - 0.14 11.9 2.1 0.23 11.2 2.1 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain Peptidase_M32 PF02074.15 ORY99949.1 - 0.054 12.3 0.1 0.069 11.9 0.1 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF3292 PF11696.8 ORY99950.1 - 3.4e-09 35.6 4.8 3.3e-05 22.5 1.6 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 ORY99950.1 - 0.0001 22.1 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 ORY99950.1 - 0.0095 15.0 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.17 ORY99950.1 - 0.13 12.2 0.7 0.22 11.5 0.7 1.4 1 0 0 1 1 1 0 Reticulon DUF639 PF04842.12 ORY99950.1 - 0.13 11.6 0.4 0.2 11.0 0.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Complex1_LYR PF05347.15 ORY99951.1 - 2.5e-08 33.9 0.7 4.9e-08 32.9 0.7 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY99951.1 - 0.00025 21.7 0.4 0.00043 21.0 0.4 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Tautomerase_2 PF14552.6 ORY99951.1 - 0.12 12.4 2.0 0.47 10.6 0.1 2.5 2 2 1 3 3 3 0 Tautomerase enzyme SE PF08491.10 ORY99952.1 - 2.9e-112 374.2 0.0 3.7e-112 373.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 ORY99952.1 - 1.4e-16 60.7 0.0 2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ORY99952.1 - 4.6e-07 29.3 0.0 7.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 ORY99952.1 - 6.1e-07 29.4 0.1 0.018 14.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY99952.1 - 0.0024 17.0 0.8 1.1 8.3 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ORY99952.1 - 0.0031 16.9 0.4 0.0049 16.3 0.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY99952.1 - 0.0053 16.0 0.0 0.042 13.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ORY99952.1 - 0.045 14.0 1.1 0.094 13.0 1.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ORY99952.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SLBB PF10531.9 ORY99952.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 SLBB domain zf-H2C2_2 PF13465.6 ORY99953.1 - 2.6e-05 24.4 6.5 0.00028 21.2 1.0 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY99953.1 - 0.00081 19.7 1.3 0.00081 19.7 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 ORY99953.1 - 0.0092 16.3 0.2 0.012 15.9 0.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY99953.1 - 0.019 15.6 0.1 0.023 15.3 0.1 1.2 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY99953.1 - 0.034 15.0 0.7 0.034 15.0 0.7 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY99953.1 - 0.041 13.9 0.2 0.041 13.9 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Consortin_C PF15281.6 ORY99954.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Consortin C-terminus Ribonucleas_3_3 PF14622.6 ORY99955.1 - 6.2e-20 71.7 0.2 4.4e-17 62.4 0.2 2.2 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY99955.1 - 0.018 15.6 0.1 0.079 13.6 0.1 2.2 1 1 0 1 1 1 0 Ribonuclease III domain bZIP_1 PF00170.21 ORY99956.1 - 1.6e-11 44.1 13.4 8.8e-08 32.1 7.9 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY99956.1 - 0.00094 19.2 17.5 0.0085 16.2 0.9 2.6 1 1 1 2 2 2 2 Basic region leucine zipper KIAA1430 PF13879.6 ORY99956.1 - 0.0034 18.1 6.1 0.0034 18.1 0.3 3.2 2 1 1 3 3 3 1 KIAA1430 homologue HAP1_N PF04849.13 ORY99956.1 - 0.0053 16.0 3.8 0.0082 15.4 3.8 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region FlaC_arch PF05377.11 ORY99956.1 - 0.025 15.0 0.4 0.049 14.0 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TMCO5 PF14992.6 ORY99956.1 - 0.037 13.6 0.8 0.054 13.1 0.8 1.2 1 0 0 1 1 1 0 TMCO5 family GIT_CC PF16559.5 ORY99956.1 - 0.039 13.8 0.6 0.088 12.7 0.6 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CCD48 PF15799.5 ORY99956.1 - 0.055 11.8 3.7 0.075 11.3 3.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 SHE3 PF17078.5 ORY99956.1 - 0.077 12.7 3.8 0.13 12.0 3.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 ORY99956.1 - 0.079 13.0 5.4 0.14 12.2 5.4 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 ORY99956.1 - 0.25 11.7 1.8 0.88 9.9 1.8 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF641 PF04859.12 ORY99956.1 - 0.76 10.1 6.7 24 5.3 0.0 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CLZ PF16526.5 ORY99956.1 - 0.94 9.9 5.6 1.9 8.9 5.6 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cep57_CLD_2 PF14197.6 ORY99956.1 - 1.4 9.1 8.8 2.6 8.2 8.8 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 SUIM_assoc PF16619.5 ORY99956.1 - 2.5 8.2 20.3 0.05 13.7 3.6 3.9 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ASD2 PF08687.11 ORY99956.1 - 3 7.3 11.0 0.37 10.3 4.2 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 PRKG1_interact PF15898.5 ORY99956.1 - 3.1 8.7 11.4 0.34 11.8 6.4 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Zn_clus PF00172.18 ORY99957.1 - 8.1e-07 29.1 8.4 1.7e-06 28.0 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY99957.1 - 0.0017 17.4 1.7 0.019 14.0 0.3 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain G_path_suppress PF15991.5 ORY99957.1 - 0.098 12.8 1.3 0.5 10.5 0.7 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor FlxA PF14282.6 ORY99957.1 - 0.12 12.4 1.0 0.21 11.6 1.0 1.3 1 0 0 1 1 1 0 FlxA-like protein Thaumatin PF00314.17 ORY99958.1 - 7.3e-53 179.4 14.9 8.7e-53 179.1 14.9 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORY99958.1 - 0.02 14.2 0.3 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Beta-1,3-glucanase Sugar_tr PF00083.24 ORY99959.1 - 2.1e-126 422.5 25.7 4.5e-126 421.3 25.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY99959.1 - 2.7e-30 105.5 63.5 3.4e-23 82.1 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF441 PF04284.13 ORY99959.1 - 0.0028 17.7 2.4 0.0028 17.7 2.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF441) AhpC-TSA PF00578.21 ORY99960.1 - 3.1e-07 30.3 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY99960.1 - 0.0069 16.1 0.0 0.0088 15.8 0.0 1.4 1 1 0 1 1 1 1 Redoxin ATP12 PF07542.11 ORY99962.1 - 2.1e-37 128.1 0.8 4.5e-37 127.0 0.8 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein DUF5059 PF16502.5 ORY99962.1 - 0.0022 16.8 0.0 0.0022 16.8 0.0 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5059) CBS PF00571.28 ORY99963.1 - 2.8e-21 75.7 2.9 4.8e-09 36.5 0.1 4.7 5 0 0 5 5 5 3 CBS domain EGF_2 PF07974.13 ORY99964.1 - 0.0032 17.8 14.4 0.0032 17.8 14.4 3.7 3 1 0 3 3 3 2 EGF-like domain hEGF PF12661.7 ORY99964.1 - 0.013 16.1 7.3 0.013 16.1 7.3 4.7 4 1 1 5 5 5 0 Human growth factor-like EGF ABC2_membrane PF01061.24 ORY99965.1 - 1.6e-40 138.8 16.5 1.6e-40 138.8 16.5 1.9 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 ORY99965.1 - 9.5e-26 90.9 0.0 1.7e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY99965.1 - 3.5e-06 27.0 0.0 0.1 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY99965.1 - 2.2e-05 24.4 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 ORY99965.1 - 3.4e-05 23.1 12.0 3.4e-05 23.1 12.0 2.6 2 1 1 3 3 3 1 ABC-2 family transporter protein Rad17 PF03215.15 ORY99965.1 - 0.0037 17.2 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 ORY99965.1 - 0.0046 16.4 0.0 0.084 12.3 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY99965.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY99965.1 - 0.008 16.6 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY99965.1 - 0.025 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY99965.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ORY99965.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_23 PF13476.6 ORY99965.1 - 0.26 11.8 0.0 0.46 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NUDIX PF00293.28 ORY99966.1 - 4.5e-16 59.1 0.7 6.4e-16 58.6 0.7 1.2 1 0 0 1 1 1 1 NUDIX domain Mem_trans PF03547.18 ORY99967.1 - 3.6e-49 167.2 3.7 7.6e-49 166.1 3.7 1.5 1 1 0 1 1 1 1 Membrane transport protein MscS_TM PF12794.7 ORY99967.1 - 3.5 6.4 16.7 4.9 5.9 2.6 2.9 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 MFS_1 PF07690.16 ORY99968.1 - 3.7e-48 164.2 30.5 1.6e-47 162.2 29.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY99968.1 - 1e-11 44.4 27.3 3.4e-09 36.1 11.0 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 ORY99968.1 - 0.00027 19.4 4.7 0.008 14.5 4.3 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family LapA_dom PF06305.11 ORY99968.1 - 0.91 9.4 10.1 0.54 10.1 0.2 3.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DAGK_cat PF00781.24 ORY99970.1 - 1.6e-23 82.7 0.2 2.8e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MFS_1 PF07690.16 ORY99970.1 - 7.2e-21 74.5 35.4 7.2e-21 74.5 35.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY99970.1 - 1.4e-09 37.3 9.8 1.4e-09 37.3 9.8 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Ribosomal_L1 PF00687.21 ORY99971.1 - 1.5e-46 158.7 1.9 1.8e-46 158.5 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 ORY99971.1 - 0.057 13.5 2.0 0.094 12.8 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function CIAPIN1 PF05093.13 ORY99971.1 - 0.14 12.7 0.2 0.35 11.4 0.1 1.8 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3176 PF11374.8 ORY99973.1 - 3.9e-14 52.7 0.0 8.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) PIG-Y PF15159.6 ORY99973.1 - 0.057 14.3 0.3 0.23 12.4 0.3 2.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Metallophos PF00149.28 ORY99975.1 - 1.8e-37 129.9 0.4 2.9e-37 129.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY99975.1 - 6.7e-05 23.2 0.1 0.00013 22.3 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain cwf21 PF08312.12 ORY99975.1 - 0.067 13.4 0.7 0.12 12.5 0.7 1.4 1 0 0 1 1 1 0 cwf21 domain Glyco_hydro_65N PF03636.15 ORY99975.1 - 0.13 11.8 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-SNAP50_C PF12251.8 ORY99976.1 - 2.1e-53 181.0 3.0 3.7e-53 180.2 3.0 1.4 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Nop14 PF04147.12 ORY99976.1 - 0.00031 19.1 33.8 0.00043 18.7 33.8 1.3 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 ORY99976.1 - 0.0062 15.9 33.7 0.01 15.2 33.7 1.3 1 0 0 1 1 1 1 BUD22 CEBP_ZZ PF16366.5 ORY99976.1 - 0.72 10.1 4.4 0.39 11.0 1.3 2.2 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF966 PF06136.13 ORY99976.1 - 3.8 7.1 20.3 12 5.5 19.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FAR1 PF03101.15 ORY99977.1 - 3.3e-05 24.5 1.9 3.3e-05 24.5 1.9 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 ORY99977.1 - 0.0027 18.1 1.3 0.0027 18.1 1.3 1.7 2 0 0 2 2 2 1 Transcription factor AFT RNA_pol_Rpb1_5 PF04998.17 ORY99978.1 - 4.9e-96 321.3 0.4 3.4e-67 226.7 0.1 2.7 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY99978.1 - 1.8e-67 226.7 0.2 4.5e-67 225.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY99978.1 - 1.1e-37 129.4 0.0 2.4e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 ORY99978.1 - 2.2e-35 122.5 4.9 1.3e-34 119.9 3.1 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 ORY99978.1 - 1.1e-23 83.2 0.2 1.1e-23 83.2 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 AAA_assoc_C PF09821.9 ORY99978.1 - 0.22 12.0 1.7 0.55 10.8 0.1 2.4 2 0 0 2 2 2 0 C-terminal AAA-associated domain CAP_GLY PF01302.25 ORY99979.1 - 1e-20 73.5 0.2 2.1e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 ORY99979.1 - 3.2e-11 43.3 8.7 0.021 15.3 0.2 4.6 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY99979.1 - 6.3e-11 42.1 3.3 8.5e-10 38.4 0.4 2.8 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 ORY99979.1 - 7.4e-11 41.7 13.1 4.5e-05 23.1 3.0 4.4 3 1 1 4 4 4 2 Leucine rich repeat Ubiquitin_2 PF14560.6 ORY99979.1 - 0.00067 20.1 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain V-SNARE_C PF12352.8 ORY99981.1 - 9.4e-11 41.8 0.6 9.4e-11 41.8 0.6 2.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY99981.1 - 1.9e-07 30.9 5.1 2.2e-07 30.7 0.1 2.7 2 1 1 3 3 3 1 Sec20 BAR_2 PF10455.9 ORY99981.1 - 0.005 16.0 3.6 0.0058 15.8 3.6 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4698 PF15769.5 ORY99981.1 - 0.0058 15.8 1.8 0.0058 15.8 1.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4698) FAM117 PF15388.6 ORY99981.1 - 0.031 13.7 0.9 0.038 13.4 0.9 1.2 1 0 0 1 1 1 0 Protein Family FAM117 DUF4047 PF13256.6 ORY99981.1 - 0.038 14.2 2.3 0.038 14.2 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Syntaxin-18_N PF10496.9 ORY99981.1 - 0.095 13.0 4.2 1.2 9.4 4.2 2.3 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus PilJ PF13675.6 ORY99981.1 - 0.13 12.3 7.8 0.21 11.6 5.2 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Helitron_like_N PF14214.6 ORY99981.1 - 0.16 12.2 3.3 0.23 11.7 0.8 2.0 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus HAUS5 PF14817.6 ORY99981.1 - 0.23 10.2 8.2 0.032 13.0 4.0 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 TPR_MLP1_2 PF07926.12 ORY99981.1 - 0.34 11.0 14.5 0.34 11.0 8.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tox-MPTase2 PF15638.6 ORY99981.1 - 1.6 8.5 7.1 0.17 11.6 0.4 2.2 2 1 0 2 2 2 0 Metallopeptidase toxin 2 SlyX PF04102.12 ORY99981.1 - 2.2 9.0 10.4 1.5 9.5 0.7 2.7 3 0 0 3 3 3 0 SlyX OmpH PF03938.14 ORY99981.1 - 5 7.5 16.3 2.2 8.6 10.6 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) E1_DerP2_DerF2 PF02221.15 ORY99982.1 - 3.4e-13 50.2 0.0 4.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ML domain Yae1_N PF09811.9 ORY99983.1 - 1.5e-07 31.0 4.6 2.7e-07 30.2 4.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Mito_carr PF00153.27 ORY99984.1 - 3.8e-43 145.3 3.4 4.3e-14 52.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HOOK PF05622.12 ORY99986.1 - 7.9e-29 100.3 0.5 9.7e-29 100.0 0.5 1.0 1 0 0 1 1 1 1 HOOK protein CH PF00307.31 ORY99986.1 - 0.053 13.7 0.1 0.21 11.8 0.0 1.9 1 1 0 2 2 2 0 Calponin homology (CH) domain Ac76 PF05814.11 ORY99986.1 - 0.48 10.5 3.9 0.77 9.8 2.6 1.9 2 0 0 2 2 2 0 Orf76 (Ac76) HOOK PF05622.12 ORY99987.1 - 3.8e-07 28.7 61.2 0.00079 17.7 29.6 3.7 1 1 2 3 3 3 3 HOOK protein Pox_A_type_inc PF04508.12 ORY99987.1 - 3.2 7.8 9.5 13 5.8 0.1 5.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat SCO1-SenC PF02630.14 ORY99988.1 - 1.1e-46 158.1 0.0 1.8e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 ORY99988.1 - 0.0032 17.8 0.0 0.0082 16.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY99988.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family DUF4080 PF13311.6 ORY99989.1 - 0.079 13.2 1.6 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) DUF5528 PF17666.1 ORY99989.1 - 7.6 6.5 12.9 0.15 12.0 0.5 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5528) zf-C2H2_jaz PF12171.8 ORY99990.1 - 4.6e-09 36.3 1.8 8.2e-09 35.5 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY99990.1 - 0.0011 19.2 1.1 0.0014 18.9 1.1 1.3 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORY99990.1 - 0.0021 18.4 0.7 0.004 17.5 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORY99990.1 - 0.033 14.7 0.3 0.074 13.5 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY99990.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.9 2 1 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.29 ORY99991.1 - 6.5e-38 130.2 0.1 3.7e-37 127.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY99991.1 - 3.1e-22 79.0 0.1 1.1e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY99991.1 - 9.9e-07 28.9 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY99991.1 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY99991.1 - 0.00062 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY99991.1 - 0.0023 18.3 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 ORY99991.1 - 0.0036 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 Helicase CMS1 PF14617.6 ORY99991.1 - 0.012 15.0 0.2 0.012 15.0 0.2 2.3 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Tubulin_2 PF13809.6 ORY99991.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin like FtsH_ext PF06480.15 ORY99991.1 - 0.17 12.2 0.0 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 FtsH Extracellular Pkinase PF00069.25 ORY99992.1 - 1.8e-70 237.3 0.0 3.2e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY99992.1 - 2.3e-54 184.4 0.0 4e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 ORY99992.1 - 1.1e-06 28.4 7.0 2.7e-06 27.2 7.0 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 ORY99992.1 - 0.0002 20.8 0.0 0.037 13.3 0.0 2.3 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 ORY99992.1 - 0.0083 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Zn_ribbon_17 PF17120.5 ORY99992.1 - 0.036 13.7 5.6 0.072 12.7 5.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 ORY99992.1 - 0.15 11.9 6.9 0.38 10.7 6.9 1.7 1 0 0 1 1 1 0 PHD-finger CH PF00307.31 ORY99993.1 - 3.1e-10 40.2 0.1 4.3e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY99993.1 - 0.0011 18.7 0.1 0.0033 17.2 0.0 1.7 1 1 1 2 2 2 1 CAMSAP CH domain Homeodomain PF00046.29 ORY99994.1 - 3.9e-18 65.0 2.4 7.3e-18 64.2 2.4 1.5 1 0 0 1 1 1 1 Homeodomain zf-met PF12874.7 ORY99995.1 - 4.1e-06 27.0 2.6 6.7e-06 26.3 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY99995.1 - 8.4e-06 25.9 1.8 1.4e-05 25.2 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 ORY99995.1 - 0.00094 19.2 0.9 0.00094 19.2 0.9 2.2 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 ORY99995.1 - 0.0016 18.1 2.2 0.0031 17.3 2.2 1.4 1 0 0 1 1 1 1 U1 zinc finger zf_C2H2_ZHX PF18387.1 ORY99995.1 - 0.0032 17.1 0.2 0.0071 16.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain DUF1168 PF06658.12 ORY99995.1 - 0.58 10.0 29.8 0.046 13.5 17.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) CPSF100_C PF13299.6 ORY99995.1 - 5 7.3 14.3 2.7 8.2 6.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pinin_SDK_memA PF04696.13 ORY99995.1 - 6 6.9 27.1 2 8.5 15.6 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region S-methyl_trans PF02574.16 ORY99996.1 - 1.5e-70 238.1 0.0 1.7e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase FMN_red PF03358.15 ORY99996.1 - 0.02 14.6 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 NADPH-dependent FMN reductase HBM PF16591.5 ORY99996.1 - 0.067 12.6 0.5 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain ECH_1 PF00378.20 ORY99997.1 - 3.4e-50 170.7 0.0 5.2e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY99997.1 - 1.1e-29 104.0 0.0 6.8e-27 94.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PDZ_5 PF17817.1 ORY99997.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Trs65 PF12735.7 ORY99998.1 - 3.9e-58 197.3 0.8 1.2e-57 195.7 0.0 2.1 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 ANAPC1 PF12859.7 ORY99998.1 - 0.058 14.0 0.2 0.058 14.0 0.2 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 1 SR-25 PF10500.9 ORY99998.1 - 3.3 7.2 7.9 1.2 8.7 1.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pyridoxal_deC PF00282.19 ORY99999.1 - 2.6e-20 72.5 0.0 4.1e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY99999.1 - 9.9e-10 37.9 0.0 2.3e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY99999.1 - 1.4e-06 27.9 0.8 1.9e-06 27.4 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.25 ORZ00103.1 - 1.4e-54 184.5 0.3 1.9e-54 184.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ00103.1 - 7.5e-39 133.7 0.2 9.4e-39 133.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORZ00103.1 - 3.8e-14 53.0 0.1 5.3e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORZ00103.1 - 9.7e-07 28.5 0.6 3.4e-06 26.7 0.6 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORZ00103.1 - 1.9e-06 27.2 0.1 2.6e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORZ00103.1 - 0.00022 21.5 0.3 0.00044 20.5 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ORZ00103.1 - 0.021 14.2 0.2 0.065 12.6 0.2 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORZ00103.1 - 0.05 12.7 0.1 0.095 11.8 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 ORZ00103.1 - 0.084 12.9 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SPRY PF00622.28 ORZ00104.1 - 4.5e-08 33.2 0.1 7.6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 SPRY domain DSPc PF00782.20 ORZ00106.1 - 9.9e-08 31.9 0.0 1.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORZ00106.1 - 2.5e-05 24.0 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORZ00106.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) ParA PF10609.9 ORZ00106.1 - 0.2 11.1 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Glyco_hydro_47 PF01532.20 ORZ00107.1 - 7.1e-166 552.6 0.0 8.5e-166 552.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 cwf21 PF08312.12 ORZ00107.1 - 7.3 6.8 5.8 10 6.4 0.1 2.9 3 0 0 3 3 3 0 cwf21 domain Ribosomal_S7e PF01251.18 ORZ00108.1 - 2e-81 272.2 2.8 2.2e-81 272.0 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4265 PF14085.6 ORZ00108.1 - 0.11 12.4 0.0 7.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) p450 PF00067.22 ORZ00109.1 - 1e-47 163.0 0.1 1.1e-47 162.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 ORZ00110.1 - 9.6e-97 324.3 0.0 1.1e-96 324.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3114 PF11311.8 ORZ00111.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) Myb_DNA-binding PF00249.31 ORZ00112.1 - 1.2e-09 38.2 0.3 2.4e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORZ00112.1 - 0.00012 21.9 0.1 0.0003 20.6 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 ORZ00112.1 - 0.0048 17.1 0.5 0.011 16.0 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2 PF00096.26 ORZ00113.1 - 0.0001 22.6 12.9 0.0003 21.1 2.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ00113.1 - 0.0049 17.2 2.6 0.0049 17.2 2.6 4.1 4 0 0 4 4 4 2 Zinc-finger double domain FOXP-CC PF16159.5 ORZ00113.1 - 0.27 11.9 12.3 0.3 11.8 0.2 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORZ00113.1 - 0.37 11.1 13.3 0.055 13.8 4.6 3.0 2 1 1 3 3 3 0 C2H2-type zinc ribbon RRM_1 PF00076.22 ORZ00114.1 - 1.3e-09 37.7 2.6 1.1e-08 34.7 0.3 2.9 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 ORZ00114.1 - 1.5e-07 31.3 0.4 2e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 La domain RRM_3 PF08777.11 ORZ00114.1 - 0.32 11.0 3.6 1.1 9.3 0.2 2.9 1 1 1 3 3 3 0 RNA binding motif RXT2_N PF08595.11 ORZ00115.1 - 6.2e-13 49.1 0.2 6.2e-13 49.1 0.2 4.0 1 1 3 4 4 4 1 RXT2-like, N-terminal RAP1 PF07218.11 ORZ00115.1 - 0.028 12.7 2.4 0.042 12.1 2.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC106 PF15794.5 ORZ00115.1 - 0.048 13.4 8.4 0.1 12.3 8.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CobT PF06213.12 ORZ00115.1 - 0.15 11.4 12.8 0.23 10.8 12.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.16 ORZ00115.1 - 0.21 11.6 1.7 0.21 11.6 1.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 ORZ00115.1 - 1.2 7.8 9.7 1.6 7.4 9.7 1.2 1 0 0 1 1 1 0 Presenilin Pap_E4 PF02711.14 ORZ00115.1 - 1.9 9.5 6.7 5.9 7.9 6.7 1.8 1 0 0 1 1 1 0 E4 protein Hid1 PF12722.7 ORZ00115.1 - 3.5 5.6 9.3 4.3 5.4 9.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 ORZ00115.1 - 4.6 5.4 13.7 6.2 5.0 13.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 ORZ00116.1 - 2.3e-29 102.4 19.0 1.2e-28 100.1 15.3 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily SPW PF03779.14 ORZ00116.1 - 0.011 15.3 0.6 0.12 12.0 0.1 2.8 2 0 0 2 2 2 0 SPW repeat Adenylsucc_synt PF00709.21 ORZ00117.1 - 4.2e-178 592.6 0.0 4.7e-178 592.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Sacchrp_dh_C PF16653.5 ORZ00118.1 - 1.6e-83 280.9 0.0 3.8e-83 279.6 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 ORZ00118.1 - 2.7e-27 95.7 0.0 1.1e-26 93.7 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 ORZ00118.1 - 1.1e-23 83.9 0.6 2.6e-23 82.7 0.6 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORZ00118.1 - 0.00044 20.3 0.2 0.0011 19.0 0.2 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ORZ00118.1 - 0.0015 17.9 0.1 0.028 13.7 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_3 PF03447.16 ORZ00118.1 - 0.0042 17.7 0.6 0.011 16.4 0.6 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ORZ00118.1 - 0.0055 17.1 0.3 0.014 15.8 0.3 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORZ00118.1 - 0.028 14.3 0.2 0.13 12.2 0.5 2.0 2 0 0 2 2 2 0 NAD(P)H-binding GFO_IDH_MocA PF01408.22 ORZ00118.1 - 0.033 15.0 0.2 0.18 12.7 0.2 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 ORZ00118.1 - 0.048 13.6 0.4 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 KR domain NAD_binding_7 PF13241.6 ORZ00118.1 - 0.091 13.2 0.3 0.21 12.1 0.3 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pribosyl_synth PF14572.6 ORZ00119.1 - 2.4e-40 138.5 2.1 2e-39 135.6 2.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORZ00119.1 - 5.7e-33 113.3 0.6 5e-32 110.3 0.2 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORZ00119.1 - 9.7e-09 34.9 0.6 9.3e-07 28.5 0.4 2.9 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORZ00119.1 - 0.0036 16.8 1.0 0.31 10.5 0.0 2.8 2 1 1 3 3 3 1 Uracil phosphoribosyltransferase RhoGAP PF00620.27 ORZ00120.1 - 9e-48 161.9 0.0 2.6e-47 160.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 ORZ00120.1 - 3.3e-23 81.9 14.7 3.9e-15 56.0 0.9 3.8 3 2 0 3 3 3 2 RasGEF N-terminal motif PH_9 PF15410.6 ORZ00120.1 - 2.8e-19 69.6 1.1 1.5e-14 54.4 0.5 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain RasGEF PF00617.19 ORZ00120.1 - 5.9e-18 65.7 0.0 5.4e-12 46.3 0.0 3.5 3 1 0 3 3 3 2 RasGEF domain PH PF00169.29 ORZ00120.1 - 4.8e-11 43.1 0.0 1.2e-05 25.8 0.0 3.0 2 0 0 2 2 2 2 PH domain Peptidase_S49_N PF08496.10 ORZ00120.1 - 0.038 14.1 1.2 0.13 12.4 1.2 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SWIRM PF04433.17 ORZ00121.1 - 6.3e-09 36.1 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain YtkA PF13115.6 ORZ00121.1 - 0.098 13.3 0.1 0.18 12.4 0.1 1.4 1 0 0 1 1 1 0 YtkA-like Anp1 PF03452.14 ORZ00122.1 - 1.7e-74 250.6 0.0 2.1e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Anp1 SgrT PF15894.5 ORZ00122.1 - 0.015 15.2 0.2 0.034 14.1 0.2 1.5 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT 2Fe-2S_thioredx PF01257.19 ORZ00123.1 - 9.6e-59 197.4 0.0 1.3e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Ras PF00071.22 ORZ00124.1 - 2.4e-61 206.1 0.1 2.8e-61 205.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ00124.1 - 6.3e-36 123.2 0.1 1.4e-35 122.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ00124.1 - 3.9e-13 49.2 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORZ00124.1 - 1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORZ00124.1 - 1.3e-05 24.7 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORZ00124.1 - 1.4e-05 25.1 0.6 0.15 11.9 0.1 2.5 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORZ00124.1 - 6.1e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORZ00124.1 - 0.002 18.5 0.1 0.005 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 ORZ00124.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 ORZ00124.1 - 0.06 12.5 0.1 0.38 9.9 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 ORZ00124.1 - 0.12 12.6 0.0 2 8.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 ORZ00124.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit p450 PF00067.22 ORZ00125.1 - 3.2e-87 293.2 0.0 3.9e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3536 PF12055.8 ORZ00125.1 - 0.028 13.7 0.3 0.29 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3536) Hormone_3 PF00159.18 ORZ00126.1 - 0.05 13.7 0.0 8.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Pancreatic hormone peptide Tfb2 PF03849.14 ORZ00126.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 Transcription factor Tfb2 Sel1 PF08238.12 ORZ00128.1 - 3.2e-129 418.4 61.2 4.8e-11 43.0 0.3 15.1 15 0 0 15 15 15 15 Sel1 repeat TPR_19 PF14559.6 ORZ00128.1 - 0.0025 18.3 0.6 0.048 14.2 0.4 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat pP_pnuc_1 PF18165.1 ORZ00128.1 - 0.1 12.5 2.0 6.4 6.7 0.0 4.1 4 2 1 5 5 5 0 Predicted pPIWI-associating nuclease Fib_succ_major PF09603.10 ORZ00128.1 - 0.75 10.4 9.9 24 5.5 0.3 5.0 1 1 2 3 3 3 0 Fibrobacter succinogenes major domain (Fib_succ_major) DUF4504 PF14953.6 ORZ00129.1 - 2.1e-11 43.7 0.0 2.7e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) polyprenyl_synt PF00348.17 ORZ00130.1 - 3.6e-66 222.8 0.0 4.2e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase TMA7 PF09072.10 ORZ00131.1 - 5.8e-27 94.3 22.3 6.4e-27 94.2 22.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Sec7 PF01369.20 ORZ00132.1 - 4.1e-27 95.0 0.2 9.3e-27 93.9 0.2 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORZ00132.1 - 2.1e-20 73.2 0.0 6.2e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain TANGO2 PF05742.12 ORZ00132.1 - 0.014 15.5 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 Transport and Golgi organisation 2 ADH_zinc_N PF00107.26 ORZ00134.1 - 6.8e-19 68.1 1.3 3.9e-18 65.7 0.5 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ00134.1 - 3.4e-10 41.1 0.1 8.7e-09 36.5 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORZ00134.1 - 8.6e-06 25.6 0.0 4e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 ORZ00134.1 - 0.0012 19.0 0.5 0.013 15.7 0.1 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.21 ORZ00134.1 - 0.0016 17.8 0.8 0.0024 17.2 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PagL PF09411.10 ORZ00134.1 - 0.14 12.3 0.2 0.56 10.4 0.1 2.0 1 1 1 2 2 2 0 Lipid A 3-O-deacylase (PagL) ADH_zinc_N PF00107.26 ORZ00135.1 - 4.9e-21 75.1 0.1 7.2e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ00135.1 - 3.7e-09 37.7 0.0 7.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORZ00135.1 - 0.0015 18.4 0.0 0.0042 17.0 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 ORZ00135.1 - 0.0043 17.2 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.21 ORZ00135.1 - 0.082 12.2 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 ORZ00135.1 - 0.1 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Avl9 PF09794.9 ORZ00136.1 - 4.3e-135 450.3 0.0 5.7e-135 449.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 ORZ00136.1 - 3.1e-13 49.7 0.0 3.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 ORZ00136.1 - 4.8e-08 32.9 0.6 0.00059 19.5 0.6 3.1 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 ORZ00136.1 - 5.6e-05 23.2 0.5 0.22 11.4 0.2 3.3 2 1 1 3 3 3 2 DENN (AEX-3) domain Afi1 PF07792.12 ORZ00136.1 - 0.47 10.9 0.0 0.47 10.9 0.0 2.6 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RCS1 PF07326.11 ORZ00137.1 - 2.9 7.7 7.1 0.53 10.2 2.9 1.8 2 0 0 2 2 2 0 Regulator of chromosome segregation 1 AhpC-TSA PF00578.21 ORZ00138.1 - 5.7e-17 61.8 0.0 7.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORZ00138.1 - 0.00099 18.8 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin ThiF PF00899.21 ORZ00139.1 - 2.3e-69 233.5 0.1 3.3e-69 233.0 0.1 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 ORZ00139.1 - 1.3e-12 48.2 4.6 1.6e-08 34.8 0.7 2.5 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 ORZ00139.1 - 3e-07 30.9 0.1 1.1e-06 29.1 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 ORZ00139.1 - 7.3e-06 26.4 0.0 2.8e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 ORZ00139.1 - 0.0002 21.5 0.1 0.00073 19.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ORZ00139.1 - 0.01 16.1 0.4 0.057 13.7 0.1 2.5 2 1 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ORZ00139.1 - 0.02 15.1 0.7 0.15 12.3 0.7 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 ORZ00139.1 - 0.061 12.5 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 ORZ00139.1 - 0.1 13.1 0.2 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EAP30 PF04157.16 ORZ00139.1 - 0.39 10.0 3.9 0.32 10.3 0.2 2.3 2 0 0 2 2 2 0 EAP30/Vps36 family ARPC4 PF05856.12 ORZ00140.1 - 1.5e-80 268.7 5.5 1.7e-80 268.5 5.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 ORZ00140.1 - 0.045 13.9 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 Sm_like domain LAG1-DNAbind PF09271.11 ORZ00141.1 - 7.3e-31 107.8 6.1 1.4e-28 100.4 3.3 3.1 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 ORZ00141.1 - 5e-20 72.3 0.0 1.6e-19 70.7 0.0 1.8 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain CcmF_C PF16327.5 ORZ00142.1 - 0.048 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Podoplanin PF05808.11 ORZ00143.1 - 0.002 18.2 2.2 0.002 18.2 2.2 1.6 2 0 0 2 2 2 1 Podoplanin EphA2_TM PF14575.6 ORZ00143.1 - 0.0082 17.0 0.0 0.017 16.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain stn_TNFRSF12A PF12191.8 ORZ00143.1 - 0.011 16.0 0.1 0.011 16.0 0.1 2.1 3 0 0 3 3 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PTP_tm PF18861.1 ORZ00143.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 ORZ00143.1 - 0.011 16.3 3.8 0.038 14.6 3.3 2.2 1 1 0 1 1 1 0 Small Novel Rich in Cartilage TMEM154 PF15102.6 ORZ00143.1 - 0.022 14.7 0.1 0.022 14.7 0.1 2.1 2 1 1 3 3 3 0 TMEM154 protein family TMEM65 PF10507.9 ORZ00143.1 - 0.032 14.2 0.6 0.058 13.4 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 65 DUF347 PF03988.12 ORZ00143.1 - 0.08 13.1 0.5 0.13 12.5 0.5 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Amnionless PF14828.6 ORZ00143.1 - 0.098 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 ORZ00143.1 - 0.11 12.5 1.2 0.21 11.5 1.2 1.4 1 0 0 1 1 1 0 Syndecan domain 7tm_3 PF00003.22 ORZ00143.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Adeno_E3_CR2 PF02439.15 ORZ00143.1 - 0.13 12.0 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VSP PF03302.13 ORZ00143.1 - 0.16 10.8 2.2 0.22 10.3 2.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein PGF-CTERM PF18204.1 ORZ00143.1 - 0.34 10.9 2.3 0.73 9.9 2.3 1.6 1 0 0 1 1 1 0 PGF-CTERM motif SKG6 PF08693.10 ORZ00143.1 - 1.3 8.5 12.2 2.7 7.5 12.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box_4 PF15966.5 ORZ00144.1 - 3.7e-05 23.6 0.3 7.9e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 ORZ00144.1 - 0.00033 20.5 1.6 0.0024 17.7 1.6 2.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORZ00144.1 - 0.00041 20.2 3.4 0.0014 18.5 3.4 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORZ00145.1 - 2.4e-05 24.2 0.3 5.6e-05 23.0 0.3 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 ORZ00145.1 - 6.6e-05 22.7 2.3 0.0002 21.2 2.3 1.9 1 0 0 1 1 1 1 F-box-like GCN5L1 PF06320.13 ORZ00147.1 - 7.7e-41 138.8 8.1 9.1e-41 138.6 8.1 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF1397 PF07165.11 ORZ00147.1 - 0.0017 17.8 0.4 0.0019 17.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) AAA_13 PF13166.6 ORZ00147.1 - 0.0068 15.1 3.7 0.0071 15.1 3.7 1.0 1 0 0 1 1 1 1 AAA domain AAA-ATPase_like PF09820.9 ORZ00147.1 - 0.0069 15.8 0.9 0.008 15.6 0.9 1.1 1 0 0 1 1 1 1 Predicted AAA-ATPase Med10 PF09748.9 ORZ00147.1 - 0.018 15.0 0.3 0.72 9.8 0.1 2.1 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Pox_polyA_pol_C PF12629.7 ORZ00147.1 - 0.023 14.5 0.2 0.025 14.4 0.2 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain Spc7 PF08317.11 ORZ00147.1 - 0.033 13.1 6.2 0.039 12.8 6.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tweety PF04906.13 ORZ00147.1 - 0.2 10.3 1.7 0.23 10.1 1.7 1.2 1 0 0 1 1 1 0 Tweety H-kinase_dim PF02895.14 ORZ00147.1 - 0.28 11.6 3.1 0.19 12.1 0.6 1.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SLX9 PF15341.6 ORZ00147.1 - 0.36 11.2 6.8 1.2 9.5 6.8 1.8 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 LMBR1 PF04791.16 ORZ00147.1 - 0.38 9.6 2.3 0.42 9.5 2.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Actin PF00022.19 ORZ00148.1 - 5.1e-23 81.3 0.0 9.2e-23 80.5 0.0 1.5 1 1 0 1 1 1 1 Actin CRA PF06589.11 ORZ00148.1 - 1.2 9.2 8.0 3.7 7.7 8.0 1.9 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) RAP1 PF07218.11 ORZ00148.1 - 6.2 5.0 10.7 1.2 7.3 7.2 1.4 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Na_Ca_ex PF01699.24 ORZ00149.1 - 3.1e-51 173.3 45.4 1e-25 90.5 19.7 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MLANA PF14991.6 ORZ00149.1 - 0.11 12.8 1.1 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein melan-A FUSC_2 PF13515.6 ORZ00150.1 - 2.1e-19 69.9 14.8 2.1e-19 69.9 14.8 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORZ00150.1 - 1.9e-18 66.4 5.5 1.9e-18 66.4 5.5 3.4 3 1 0 4 4 4 2 Fusaric acid resistance protein family ALMT PF11744.8 ORZ00150.1 - 4e-13 49.0 6.2 4e-13 49.0 6.2 2.9 2 1 0 2 2 2 1 Aluminium activated malate transporter ArAE_2 PF10334.9 ORZ00150.1 - 5.8e-13 49.2 0.2 1.6e-12 47.8 0.2 1.8 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 SPC12 PF06645.13 ORZ00150.1 - 0.044 13.9 0.0 0.044 13.9 0.0 4.6 3 1 1 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) F-box-like PF12937.7 ORZ00151.1 - 7e-06 25.8 0.9 1.4e-05 24.9 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ00151.1 - 0.00011 21.9 0.0 0.00036 20.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORZ00151.1 - 0.0034 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 F-box Pkinase PF00069.25 ORZ00152.1 - 1.8e-24 86.5 0.0 2.3e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 ORZ00152.1 - 3.8e-12 45.7 0.0 5.2e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 ORZ00152.1 - 7e-07 28.8 0.0 9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORZ00152.1 - 5.9e-05 23.1 0.0 0.02 14.8 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Gpr1_Fun34_YaaH PF01184.19 ORZ00153.1 - 7.7e-75 251.0 11.0 9e-75 250.8 11.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 ORZ00153.1 - 5.4 7.5 17.2 0.73 10.3 0.7 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF202) Aldolase_II PF00596.21 ORZ00154.1 - 4e-47 160.5 0.0 5.2e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain G-patch PF01585.23 ORZ00154.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 G-patch domain Spt5-NGN PF03439.13 ORZ00155.1 - 1.1e-22 79.7 0.0 2.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 ORZ00155.1 - 2.1e-18 65.6 22.0 0.00012 21.9 0.1 7.4 8 0 0 8 8 8 5 KOW motif CTD PF12815.7 ORZ00155.1 - 4.3e-16 59.2 54.4 3.1e-10 40.5 10.7 4.0 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 ORZ00155.1 - 1.6e-15 57.9 12.4 1.6e-15 57.9 12.4 3.2 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 ORZ00155.1 - 0.00069 19.8 0.7 0.19 12.0 0.1 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) PCB_OB PF17092.5 ORZ00155.1 - 0.0024 18.6 0.6 7.9 7.3 0.0 3.7 3 1 0 3 3 3 2 Penicillin-binding protein OB-like domain DUF150_C PF17384.2 ORZ00155.1 - 0.025 14.7 1.2 0.074 13.2 0.2 2.4 2 0 0 2 2 2 0 RimP C-terminal SH3 domain DUF3659 PF12396.8 ORZ00155.1 - 0.032 14.2 1.7 3.6 7.6 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) MBOAT PF03062.19 ORZ00156.1 - 2.9e-48 165.0 26.4 2.9e-48 165.0 26.4 2.1 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family SNF5 PF04855.12 ORZ00157.1 - 2.3e-58 197.8 6.0 1.6e-31 109.9 0.3 2.3 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 COX7C PF02935.16 ORZ00161.1 - 1.5e-16 60.4 0.1 1.6e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Arginosuc_synth PF00764.19 ORZ00162.1 - 1.4e-147 492.0 0.0 1.7e-147 491.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORZ00162.1 - 0.0074 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORZ00162.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DSPc PF00782.20 ORZ00163.1 - 8.9e-27 93.5 0.0 1.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 ORZ00163.1 - 0.0018 18.6 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain MFS_1 PF07690.16 ORZ00164.1 - 2.2e-30 105.8 34.6 2.7e-30 105.5 34.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Desulfoferrod_N PF06397.12 ORZ00165.1 - 0.17 11.5 3.8 0.3 10.8 3.8 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Gln-synt_C PF00120.24 ORZ00166.1 - 1.4e-83 280.7 0.0 1.8e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain MFS_1 PF07690.16 ORZ00167.1 - 1e-12 47.7 32.3 1e-12 47.7 32.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ORZ00167.1 - 1.3e-06 28.1 4.8 1.3e-06 28.1 4.8 1.9 2 0 0 2 2 2 1 Nodulin-like FAM176 PF14851.6 ORZ00167.1 - 0.077 12.7 0.9 0.21 11.2 0.9 1.7 1 0 0 1 1 1 0 FAM176 family RBFA PF02033.18 ORZ00168.1 - 1.3e-07 32.0 0.0 1.8e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome-binding factor A Asp PF00026.23 ORZ00169.1 - 2.7e-84 283.3 2.6 3.1e-64 217.4 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORZ00169.1 - 1.6e-10 41.5 0.4 2.4e-09 37.7 0.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORZ00169.1 - 1e-05 25.4 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal SDA1 PF05285.12 ORZ00169.1 - 0.25 10.8 8.1 0.32 10.4 8.1 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 ORZ00169.1 - 0.26 10.4 16.0 0.35 10.0 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 ORZ00169.1 - 1.3 7.3 8.9 1.8 6.8 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORZ00169.1 - 2.2 6.4 13.1 2.9 6.0 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 ORZ00169.1 - 4.7 6.9 6.2 7.2 6.3 6.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 ORZ00169.1 - 4.7 5.2 18.1 6.1 4.8 18.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi GPI-anchored PF10342.9 ORZ00170.1 - 0.017 15.8 0.1 0.065 14.0 0.1 1.8 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NPCBM_assoc PF10633.9 ORZ00170.1 - 0.024 14.9 0.1 0.044 14.0 0.1 1.4 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Big_7 PF17957.1 ORZ00170.1 - 0.06 14.1 0.8 0.31 11.8 0.2 2.0 2 0 0 2 2 2 0 Bacterial Ig domain RRM_1 PF00076.22 ORZ00171.1 - 3.7e-17 61.9 0.1 7.4e-17 60.9 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORZ00171.1 - 6.2e-09 35.5 0.0 7.2e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ00171.1 - 0.056 13.6 0.2 0.19 11.9 0.2 2.0 1 1 0 1 1 1 0 RNA recognition motif GST_N_3 PF13417.6 ORZ00172.1 - 6.2e-15 55.4 0.1 1.4e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORZ00172.1 - 1e-06 28.9 0.0 3.4e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORZ00172.1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORZ00172.1 - 0.15 12.8 0.0 0.45 11.3 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain PBP PF01161.20 ORZ00173.1 - 7.3e-11 42.5 0.5 9.3e-11 42.2 0.5 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Prp18 PF02840.15 ORZ00174.1 - 4.1e-61 205.2 1.6 4.1e-61 205.2 1.6 2.4 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 ORZ00174.1 - 1.6e-10 40.3 0.9 5.2e-10 38.7 0.9 2.0 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Sel1 PF08238.12 ORZ00175.1 - 7.5e-22 77.3 8.5 1.3e-09 38.4 0.8 4.1 4 0 0 4 4 4 3 Sel1 repeat TPR_1 PF00515.28 ORZ00175.1 - 0.6 10.0 0.0 0.6 10.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00175.1 - 2.2 9.0 6.3 0.53 11.0 1.0 2.5 3 1 0 3 3 3 0 Tetratricopeptide repeat LapA_dom PF06305.11 ORZ00176.1 - 0.0057 16.4 0.1 0.0088 15.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Phage_holin_2_4 PF16082.5 ORZ00176.1 - 0.016 14.9 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4381 PF14316.6 ORZ00176.1 - 0.021 15.0 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pox_A14 PF05767.12 ORZ00176.1 - 0.023 14.9 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 YajC PF02699.15 ORZ00176.1 - 0.023 14.6 0.6 0.039 13.8 0.6 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit EphA2_TM PF14575.6 ORZ00176.1 - 0.025 15.4 0.0 0.035 15.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2269 PF10027.9 ORZ00176.1 - 0.031 14.3 0.2 0.046 13.8 0.2 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) TMEM51 PF15345.6 ORZ00176.1 - 0.032 14.1 0.2 0.032 14.1 0.2 1.8 1 1 1 2 2 2 0 Transmembrane protein 51 MscL PF01741.18 ORZ00176.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Miga PF10265.9 ORZ00176.1 - 0.11 11.5 0.6 0.14 11.1 0.6 1.3 1 1 0 1 1 1 0 Mitoguardin FAM70 PF14967.6 ORZ00176.1 - 0.11 11.9 1.0 0.14 11.6 1.0 1.1 1 0 0 1 1 1 0 FAM70 protein GRIM-19 PF06212.12 ORZ00176.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 GRIM-19 protein Acyl-CoA_dh_1 PF00441.24 ORZ00177.1 - 1.6e-49 168.0 5.4 2.6e-49 167.3 5.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORZ00177.1 - 1.7e-28 98.6 0.2 1.2e-27 96.0 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORZ00177.1 - 2.3e-25 89.5 0.1 5.3e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORZ00177.1 - 4.3e-18 65.9 4.0 4.3e-18 65.9 4.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORZ00177.1 - 0.0016 18.2 0.9 0.0073 16.0 0.3 2.4 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Methyltransf_25 PF13649.6 ORZ00178.1 - 3.1e-16 59.8 0.0 8.6e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ00178.1 - 4.1e-14 53.0 0.0 8.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ00178.1 - 6.6e-13 48.7 0.0 1.6e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ00178.1 - 1.1e-09 38.9 0.0 2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ00178.1 - 6.6e-09 35.4 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORZ00178.1 - 9.9e-09 35.2 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORZ00178.1 - 2.8e-05 23.7 0.0 0.0001 21.8 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.12 ORZ00178.1 - 6.4e-05 22.6 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ORZ00178.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORZ00178.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 ORZ00178.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_8 PF05148.15 ORZ00178.1 - 0.041 13.7 0.0 0.29 11.0 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.18 ORZ00178.1 - 0.046 13.2 0.1 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 ORZ00178.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 ORZ00178.1 - 0.19 11.7 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 ORZ00178.1 - 0.23 10.4 0.0 0.23 10.4 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) IBN_N PF03810.19 ORZ00178.1 - 1.4 8.9 5.0 0.71 9.8 0.2 2.5 3 0 0 3 3 3 0 Importin-beta N-terminal domain FAM76 PF16046.5 ORZ00180.1 - 0.0044 16.4 1.2 0.0053 16.2 1.2 1.1 1 0 0 1 1 1 1 FAM76 protein TPD52 PF04201.15 ORZ00180.1 - 0.01 15.4 0.3 0.015 14.9 0.3 1.2 1 0 0 1 1 1 0 Tumour protein D52 family HisKA_4TM PF16926.5 ORZ00180.1 - 0.02 14.5 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase DUF641 PF04859.12 ORZ00180.1 - 0.1 12.9 0.4 0.17 12.2 0.4 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ACBP PF00887.19 ORZ00181.1 - 1.4e-22 79.7 0.0 1.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein TMEM223 PF14640.6 ORZ00182.1 - 8.1e-07 29.4 0.1 0.013 15.7 0.0 2.0 1 1 1 2 2 2 2 Transmembrane protein 223 Iso_dh PF00180.20 ORZ00184.1 - 2.1e-80 270.5 0.0 2.5e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase mRNA_cap_enzyme PF01331.19 ORZ00185.1 - 1.5e-22 80.4 0.0 1.8e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ORZ00186.1 - 9.9e-15 55.1 0.0 2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 ORZ00186.1 - 4.1e-08 33.3 0.1 6.5e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain SpoU_methylase PF00588.19 ORZ00187.1 - 1.4e-26 93.4 0.0 2.9e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family PMEI PF04043.15 ORZ00187.1 - 0.045 14.1 1.0 10 6.4 0.2 2.8 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor PRELI PF04707.14 ORZ00188.1 - 3.9e-45 153.5 0.4 4.8e-45 153.2 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family DUF3295 PF11702.8 ORZ00189.1 - 0.21 10.9 6.5 0.27 10.5 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) GATA PF00320.27 ORZ00189.1 - 5.1 6.8 12.9 25 4.6 0.3 3.9 4 0 0 4 4 4 0 GATA zinc finger Pex16 PF08610.10 ORZ00190.1 - 3e-108 361.8 3.5 3.4e-108 361.7 3.5 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) AWPM-19 PF05512.11 ORZ00190.1 - 0.011 15.9 0.4 0.023 14.9 0.4 1.5 1 0 0 1 1 1 0 AWPM-19-like family Zn_Tnp_IS1595 PF12760.7 ORZ00192.1 - 0.0034 17.3 2.6 0.0056 16.6 2.6 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 ORZ00192.1 - 0.0063 16.9 0.5 0.011 16.1 0.5 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar TFIIS_C PF01096.18 ORZ00192.1 - 0.024 14.5 3.6 4 7.4 0.1 3.0 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) CxC3 PF18804.1 ORZ00192.1 - 0.071 13.0 2.2 0.088 12.7 2.2 1.3 1 1 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases C1_4 PF07975.12 ORZ00192.1 - 0.22 11.8 3.6 2.6 8.3 0.3 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-DNL PF05180.12 ORZ00193.1 - 2.5e-32 110.6 0.3 2.8e-32 110.5 0.3 1.0 1 0 0 1 1 1 1 DNL zinc finger Smg8_Smg9 PF10220.9 ORZ00194.1 - 7.2e-06 24.6 0.0 1.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Smg8_Smg9 GBP PF02263.19 ORZ00194.1 - 5.2e-05 22.7 0.3 0.00014 21.2 0.3 1.6 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 ORZ00194.1 - 0.00012 22.1 0.0 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORZ00194.1 - 0.15 12.1 0.1 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Dynamin family Proteasome PF00227.26 ORZ00195.1 - 2.2e-51 174.0 0.6 2.5e-51 173.9 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 ORZ00196.1 - 4.1e-12 46.4 3.9 0.001 19.8 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00196.1 - 0.0015 18.8 0.0 1.6 9.0 0.0 3.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4442 PF14539.6 ORZ00198.1 - 5.6e-23 81.5 0.0 1.2e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) F-box-like PF12937.7 ORZ00198.1 - 1.6e-10 40.7 0.2 3.1e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ00198.1 - 1.5e-06 27.9 0.2 3e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 ORZ00198.1 - 0.0019 18.2 0.4 0.0068 16.4 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ00198.1 - 0.0022 17.8 0.1 0.0052 16.6 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ00198.1 - 0.0024 17.5 0.0 0.022 14.4 0.0 2.2 1 1 1 2 2 2 1 TPR repeat 4HBT PF03061.22 ORZ00198.1 - 0.13 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Thioesterase superfamily Ribosomal_L34e PF01199.18 ORZ00199.1 - 9.9e-46 154.0 5.1 1.4e-45 153.5 5.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 ORZ00199.1 - 0.18 11.8 4.1 1.4 9.0 0.3 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Sugar_tr PF00083.24 ORZ00200.1 - 2e-50 172.0 20.2 2.5e-50 171.7 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ00200.1 - 7.7e-21 74.4 35.1 3.6e-14 52.5 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2569 PF10754.9 ORZ00200.1 - 0.64 10.4 7.3 0.27 11.7 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Ribosomal_S11 PF00411.19 ORZ00201.1 - 4.6e-22 78.5 0.1 9.1e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 Aminotran_3 PF00202.21 ORZ00202.1 - 2.4e-111 372.3 0.0 3.1e-111 371.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORZ00202.1 - 0.042 13.0 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II SF3A2 PF16835.5 ORZ00203.1 - 2.8e-40 136.6 0.1 4.3e-40 136.0 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 ORZ00203.1 - 9.9e-08 32.1 2.9 1e-07 32.1 1.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 ORZ00203.1 - 0.0015 18.0 0.5 0.0027 17.2 0.5 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 ORZ00203.1 - 0.0026 17.7 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PTR2 PF00854.21 ORZ00204.1 - 1.6e-86 290.6 7.3 1.6e-86 290.6 7.3 1.7 1 1 0 1 1 1 1 POT family NUDIX PF00293.28 ORZ00205.1 - 0.097 12.7 2.0 0.33 11.0 1.0 2.3 1 1 1 2 2 2 0 NUDIX domain ECH_2 PF16113.5 ORZ00206.1 - 6.1e-121 404.0 0.0 5.3e-120 400.9 0.0 2.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORZ00206.1 - 2e-24 86.3 0.0 1.3e-13 50.8 0.0 3.1 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase FliG_N PF14842.6 ORZ00206.1 - 0.019 15.5 0.1 0.056 14.0 0.0 1.8 2 0 0 2 2 2 0 FliG N-terminal domain Pex2_Pex12 PF04757.14 ORZ00208.1 - 2.2e-32 112.5 5.7 2.7e-32 112.2 5.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 ORZ00208.1 - 3.5e-09 36.4 10.1 6.3e-09 35.6 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORZ00208.1 - 1.1e-08 35.2 14.0 2e-08 34.4 14.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORZ00208.1 - 5.7e-08 32.5 12.8 1e-07 31.7 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORZ00208.1 - 5.4e-07 29.4 11.6 9.5e-07 28.6 11.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORZ00208.1 - 5.7e-07 29.3 13.8 1e-06 28.4 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ00208.1 - 0.00013 21.8 10.2 0.00027 20.8 10.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORZ00208.1 - 0.00022 21.4 9.2 0.00049 20.3 9.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORZ00208.1 - 0.00023 21.1 8.1 0.00023 21.1 8.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger DUF4748 PF15932.5 ORZ00208.1 - 0.0079 15.9 0.1 0.026 14.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) zf-C3HC4_4 PF15227.6 ORZ00208.1 - 0.036 14.2 12.5 0.11 12.7 12.5 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING AIF_C PF14721.6 ORZ00208.1 - 0.082 13.3 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Baculo_IE-1 PF05290.11 ORZ00208.1 - 0.11 12.5 3.6 0.3 11.0 3.6 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 ORZ00208.1 - 0.86 9.8 8.8 1.8 8.8 8.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 ORZ00208.1 - 6.4 6.6 6.8 1.1 9.0 2.7 1.9 2 0 0 2 2 2 0 RING-like zinc finger DASH_Dad3 PF08656.10 ORZ00209.1 - 0.0068 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad3 CBP_GIL PF10995.8 ORZ00209.1 - 0.12 11.0 0.1 0.15 10.7 0.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis GIL Mito_carr PF00153.27 ORZ00210.1 - 3.6e-58 193.5 5.4 3.8e-20 71.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein KCH PF16944.5 ORZ00210.1 - 0.017 14.9 1.0 0.033 14.0 1.0 1.5 1 1 0 1 1 1 0 Fungal potassium channel Wzz PF02706.15 ORZ00210.1 - 0.041 14.2 0.0 0.17 12.2 0.0 2.1 1 1 0 1 1 1 0 Chain length determinant protein PrcB_C PF14343.6 ORZ00210.1 - 0.055 13.6 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 PrcB C-terminal MtrF PF09472.10 ORZ00210.1 - 0.16 11.4 1.5 0.45 9.9 0.5 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) RhoGEF PF00621.20 ORZ00211.1 - 7.3e-23 81.7 0.7 1.4e-22 80.8 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PLU-1 PF08429.11 ORZ00211.1 - 0.082 12.1 0.8 0.23 10.6 0.8 1.8 1 1 0 1 1 1 0 PLU-1-like protein GFO_IDH_MocA PF01408.22 ORZ00212.1 - 8.8e-24 84.6 1.1 1.7e-23 83.7 1.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORZ00212.1 - 0.00083 20.0 0.9 0.0018 18.9 0.9 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORZ00212.1 - 0.0017 18.9 1.1 0.0035 17.9 0.1 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORZ00212.1 - 0.051 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA_C PF02894.17 ORZ00212.1 - 0.08 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain AAA PF00004.29 ORZ00213.1 - 2.5e-83 277.1 0.0 2.5e-42 144.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ00213.1 - 1.6e-28 98.2 0.4 6.2e-16 57.9 0.0 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORZ00213.1 - 2.5e-14 54.0 1.5 2.2e-06 28.1 0.5 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 ORZ00213.1 - 4.6e-13 49.4 0.0 4.9e-07 29.8 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORZ00213.1 - 1.1e-11 44.8 0.1 0.00026 20.8 0.0 3.9 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORZ00213.1 - 4.5e-10 39.9 0.0 1.9e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 ORZ00213.1 - 4.3e-09 36.2 0.9 0.0036 16.9 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.6 ORZ00213.1 - 1.6e-08 34.9 2.7 0.33 11.2 0.1 4.3 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.6 ORZ00213.1 - 9.3e-07 28.9 0.0 0.049 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORZ00213.1 - 1.2e-06 28.9 0.0 0.018 15.4 0.0 2.4 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 ORZ00213.1 - 1.8e-06 27.4 0.0 0.042 13.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 ORZ00213.1 - 2.2e-06 27.7 0.1 0.00015 21.8 0.0 2.8 2 1 0 3 3 3 1 Rad17 P-loop domain AAA_7 PF12775.7 ORZ00213.1 - 4.9e-06 26.2 0.0 0.013 15.0 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 ORZ00213.1 - 9.4e-06 25.7 0.0 0.18 11.7 0.0 2.8 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea NACHT PF05729.12 ORZ00213.1 - 1.3e-05 25.2 0.1 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 ORZ00213.1 - 1.7e-05 25.0 0.0 0.018 15.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORZ00213.1 - 1.8e-05 24.7 0.0 0.12 12.3 0.0 2.8 2 2 0 2 2 2 2 NTPase AAA_3 PF07726.11 ORZ00213.1 - 2.5e-05 24.2 0.0 0.14 12.1 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORZ00213.1 - 0.00011 22.0 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORZ00213.1 - 0.00012 22.6 0.1 0.15 12.6 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 ORZ00213.1 - 0.00016 22.3 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ORZ00213.1 - 0.00023 21.2 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 ORZ00213.1 - 0.00025 20.9 0.0 0.013 15.3 0.0 2.6 2 1 0 2 2 2 1 IstB-like ATP binding protein KAP_NTPase PF07693.14 ORZ00213.1 - 0.00052 19.4 0.0 0.81 8.9 0.0 3.0 3 0 0 3 3 3 1 KAP family P-loop domain AAA_11 PF13086.6 ORZ00213.1 - 0.00066 19.5 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ORZ00213.1 - 0.0012 18.3 0.1 0.91 8.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 ORZ00213.1 - 0.0016 17.7 0.0 0.82 8.8 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain Bac_DnaA PF00308.18 ORZ00213.1 - 0.0024 17.7 0.0 0.15 11.9 0.0 3.1 3 1 0 3 3 3 1 Bacterial dnaA protein AAA_28 PF13521.6 ORZ00213.1 - 0.0024 18.1 0.0 0.78 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORZ00213.1 - 0.003 17.9 0.2 2.8 8.3 0.0 3.3 2 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 ORZ00213.1 - 0.003 17.3 0.0 0.76 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ORZ00213.1 - 0.0039 17.0 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.10 ORZ00213.1 - 0.0087 16.0 0.0 0.82 9.7 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 ORZ00213.1 - 0.017 14.3 0.0 4.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 ORZ00213.1 - 0.018 14.0 0.0 0.87 8.4 0.0 2.6 3 0 0 3 3 3 0 AFG1-like ATPase AAA_17 PF13207.6 ORZ00213.1 - 0.035 14.5 0.0 9.3 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 ORZ00213.1 - 0.054 12.6 0.0 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Sigma54_activat PF00158.26 ORZ00213.1 - 0.059 13.1 0.0 11 5.7 0.0 3.3 3 1 0 3 3 3 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 ORZ00213.1 - 0.086 12.7 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 ORZ00213.1 - 0.088 12.6 0.0 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORZ00213.1 - 0.13 11.5 0.0 7.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin UvdE PF03851.14 ORZ00214.1 - 2.9e-101 338.3 0.1 5.3e-101 337.5 0.0 1.4 2 0 0 2 2 2 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 ORZ00214.1 - 0.00015 21.3 0.0 0.003 17.0 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Xin PF08043.12 ORZ00214.1 - 4.1 7.2 5.7 26 4.6 0.5 2.6 2 0 0 2 2 2 0 Xin repeat Acyl_transf_1 PF00698.21 ORZ00216.1 - 3.6e-22 79.3 0.1 5.1e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ribosomal_L31 PF01197.18 ORZ00217.1 - 1.6e-06 28.3 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 Fe-ADH PF00465.19 ORZ00217.1 - 0.16 10.7 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase SNF2_N PF00176.23 ORZ00218.1 - 5.3e-56 189.8 0.0 9.8e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORZ00218.1 - 8.7e-18 64.7 0.0 2e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 ORZ00218.1 - 8e-16 57.7 7.7 1.1e-10 41.2 0.1 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 ORZ00218.1 - 1.2e-05 25.3 0.0 5.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORZ00218.1 - 0.00088 18.5 1.1 0.0085 15.3 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SLIDE PF09111.10 ORZ00218.1 - 0.0022 18.0 1.2 0.064 13.3 0.0 3.5 3 0 0 3 3 3 1 SLIDE Myb_DNA-binding PF00249.31 ORZ00218.1 - 0.0036 17.5 0.4 0.12 12.6 0.0 3.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ToxN_toxin PF13958.6 ORZ00218.1 - 0.1 12.8 0.8 0.94 9.7 0.3 2.6 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system Mito_carr PF00153.27 ORZ00219.1 - 2.6e-61 203.5 1.8 1.9e-19 69.4 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 ORZ00219.1 - 0.1 12.7 0.0 25 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) Bap31 PF05529.12 ORZ00221.1 - 3.6e-34 117.5 6.1 4.6e-34 117.2 6.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region PHR PF08005.12 ORZ00221.1 - 0.051 14.3 0.2 0.12 13.1 0.2 1.5 1 1 0 1 1 1 0 PHR domain HSF_DNA-bind PF00447.17 ORZ00222.1 - 3.4e-28 98.1 0.3 6.6e-28 97.2 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Tup_N PF08581.10 ORZ00222.1 - 0.074 13.4 1.5 0.079 13.3 0.0 1.8 2 0 0 2 2 2 0 Tup N-terminal DUF1647 PF07801.11 ORZ00222.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) RasGEF PF00617.19 ORZ00224.1 - 2.1e-59 200.7 0.5 2.1e-59 200.7 0.5 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 ORZ00224.1 - 3.3e-27 94.8 0.3 1.2e-26 92.9 0.3 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.26 ORZ00224.1 - 9.1e-15 54.5 6.4 1.3e-08 34.8 1.9 2.8 2 0 0 2 2 2 2 WW domain SH3_1 PF00018.28 ORZ00224.1 - 8.6e-14 50.9 0.4 2e-13 49.7 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORZ00224.1 - 6.5e-11 41.7 0.1 1.6e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORZ00224.1 - 8.7e-11 41.5 0.3 1.9e-10 40.5 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SCVP PF17619.2 ORZ00224.1 - 0.058 14.3 0.0 0.23 12.3 0.0 2.1 1 0 0 1 1 1 0 Secreted clade V proteins Syntaxin_2 PF14523.6 ORZ00224.1 - 5.1 7.5 6.4 1.3e+02 3.0 0.4 4.6 5 0 0 5 5 5 0 Syntaxin-like protein Med24_N PF11277.8 ORZ00225.1 - 0.00053 18.2 0.0 0.63 8.0 0.0 2.5 2 1 0 2 2 2 2 Mediator complex subunit 24 N-terminal SUIM_assoc PF16619.5 ORZ00225.1 - 0.38 10.9 6.7 0.2 11.7 1.6 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PTPA PF03095.15 ORZ00226.1 - 1.1e-121 406.0 0.0 1.2e-121 405.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FtsJ PF01728.19 ORZ00227.1 - 1.1e-33 116.9 0.0 1.5e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase FAD_binding_3 PF01494.19 ORZ00228.1 - 3.7e-69 233.6 0.0 5.2e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORZ00228.1 - 0.0009 18.0 0.0 0.046 12.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ORZ00228.1 - 0.0092 16.2 0.1 0.032 14.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ORZ00228.1 - 0.024 14.3 0.1 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 ORZ00228.1 - 0.025 14.2 0.4 0.071 12.7 0.1 1.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORZ00228.1 - 0.041 13.1 0.1 0.16 11.2 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORZ00228.1 - 0.053 14.1 0.0 2.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Vma12 PF11712.8 ORZ00230.1 - 1.1e-08 35.2 0.4 1.3e-08 35.0 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Glyco_hydro_38 PF18438.1 ORZ00230.1 - 0.025 14.6 0.2 0.1 12.6 0.1 1.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 XRCC4 PF06632.12 ORZ00231.1 - 0.0005 19.0 6.1 0.0084 15.0 6.1 2.1 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PdxJ PF03740.13 ORZ00231.1 - 0.033 13.3 0.4 0.047 12.8 0.4 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Hemagglutinin PF00509.18 ORZ00231.1 - 0.075 11.4 0.5 0.11 10.9 0.5 1.1 1 0 0 1 1 1 0 Haemagglutinin SKA1 PF07160.12 ORZ00231.1 - 0.2 11.4 5.3 0.47 10.3 5.3 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Spt20 PF12090.8 ORZ00232.1 - 1.4e-05 24.8 8.6 2e-05 24.4 8.6 1.2 1 0 0 1 1 1 1 Spt20 family DDHD PF02862.17 ORZ00232.1 - 0.042 14.0 0.5 0.065 13.4 0.5 1.3 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.10 ORZ00232.1 - 0.26 9.9 3.4 0.41 9.3 3.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 ORZ00232.1 - 0.49 9.1 5.9 0.69 8.6 5.9 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 ORZ00232.1 - 4.5 7.2 16.5 6.4 6.7 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.10 ORZ00232.1 - 4.5 6.9 8.5 7.7 6.1 8.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3464 PF11947.8 ORZ00232.1 - 5.3 6.8 8.9 9.1 6.0 8.9 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TERB2 PF15101.6 ORZ00232.1 - 7.1 6.6 10.2 15 5.6 10.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Roughex PF06020.11 ORZ00232.1 - 7.3 5.6 10.0 10 5.1 10.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Usp PF00582.26 ORZ00233.1 - 4.9e-18 66.0 0.9 9.5e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family PP2C PF00481.21 ORZ00234.1 - 5e-51 173.8 1.8 1.2e-50 172.5 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 ORZ00234.1 - 5.7e-42 141.3 58.1 1e-08 34.8 1.1 10.7 6 3 7 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 ORZ00234.1 - 3.7e-32 109.8 66.1 0.00092 19.6 0.2 12.7 5 3 5 13 13 13 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 ORZ00234.1 - 4.6e-29 101.3 0.0 1.3e-28 99.9 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain RA PF00788.23 ORZ00234.1 - 2.2e-06 28.2 0.0 5.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 ORZ00234.1 - 0.002 17.7 0.8 0.002 17.7 0.8 4.8 3 1 3 6 6 6 2 Leucine-rich repeat LRR_1 PF00560.33 ORZ00234.1 - 0.042 14.4 54.2 2.3 9.1 0.0 14.6 14 3 0 14 14 14 0 Leucine Rich Repeat TFIIA PF03153.13 ORZ00234.1 - 9.6 6.1 25.2 18 5.2 25.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_2 PF13923.6 ORZ00235.1 - 6.5e-09 35.5 12.4 6.5e-09 35.5 12.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORZ00235.1 - 4.9e-08 33.0 8.0 4.9e-08 33.0 8.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORZ00235.1 - 5.1e-08 32.7 7.5 5.1e-08 32.7 7.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORZ00235.1 - 2.1e-06 27.6 7.1 7.5e-06 25.9 7.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORZ00235.1 - 2.8e-06 27.5 12.9 2.8e-06 27.5 12.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORZ00235.1 - 4.4e-06 26.4 15.0 9.6e-06 25.4 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ00235.1 - 0.00017 21.5 12.3 0.00017 21.5 12.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 ORZ00235.1 - 0.12 12.5 4.8 0.27 11.4 4.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORZ00235.1 - 1.3 9.3 16.3 0.092 13.0 9.9 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain DUF1272 PF06906.11 ORZ00235.1 - 1.8 8.7 14.6 0.066 13.3 6.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 ORZ00235.1 - 3.4 7.8 11.5 9.3 6.4 4.8 2.7 2 1 0 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.6 ORZ00235.1 - 6.6 6.7 14.3 0.073 12.9 6.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 F-box-like PF12937.7 ORZ00236.1 - 1.1e-06 28.4 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ00236.1 - 0.0013 18.6 1.3 0.002 17.9 0.2 2.0 2 2 0 2 2 2 1 F-box domain SAM_decarbox PF01536.16 ORZ00237.1 - 3.5e-112 375.0 0.0 4.1e-112 374.7 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Lgl_C PF08596.10 ORZ00238.1 - 2.9e-07 29.5 0.0 9.6e-07 27.8 0.1 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 ORZ00239.1 - 2.7e-07 30.8 0.0 0.0037 17.5 0.0 3.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORZ00239.1 - 2.1e-06 28.3 2.1 0.0017 19.2 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ELYS-bb PF16687.5 ORZ00239.1 - 0.02 13.6 0.0 3.9 6.0 0.0 2.2 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin LLGL PF08366.13 ORZ00239.1 - 0.02 15.2 0.0 0.098 13.0 0.0 2.0 2 0 0 2 2 2 0 LLGL2 Tox-PLDMTX PF15645.6 ORZ00239.1 - 0.13 12.5 0.0 5.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold Aldo_ket_red PF00248.21 ORZ00240.1 - 3.3e-55 187.4 0.1 2.4e-54 184.5 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family zf-RING_2 PF13639.6 ORZ00241.1 - 5e-14 52.4 4.1 1e-13 51.4 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORZ00241.1 - 7.3e-11 41.6 2.4 7.3e-11 41.6 2.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORZ00241.1 - 4.5e-08 32.8 4.1 8.3e-08 31.9 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ00241.1 - 5.9e-08 32.5 3.3 1e-07 31.7 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 ORZ00241.1 - 2.1e-07 30.9 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 ORZ00241.1 - 2.9e-07 30.3 2.7 5.3e-07 29.5 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORZ00241.1 - 1.3e-06 28.6 8.8 1e-05 25.7 8.8 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORZ00241.1 - 1.9e-05 24.4 3.5 3.7e-05 23.5 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORZ00241.1 - 0.00023 21.1 0.3 0.00023 21.1 0.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORZ00241.1 - 0.00042 20.1 3.7 0.00076 19.3 3.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORZ00241.1 - 0.0089 16.1 3.7 0.033 14.2 3.7 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 ORZ00241.1 - 0.012 15.4 2.6 0.024 14.5 2.6 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 ORZ00241.1 - 0.016 14.9 3.9 0.04 13.5 3.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORZ00241.1 - 0.035 14.3 6.1 0.24 11.6 6.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 ORZ00241.1 - 0.061 13.5 2.2 0.18 11.9 2.2 1.9 1 1 0 1 1 1 0 RING-variant domain DUF4083 PF13314.6 ORZ00241.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) zf-RING-like PF08746.11 ORZ00241.1 - 0.23 11.8 3.3 0.44 10.9 3.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 ORZ00241.1 - 0.31 11.2 3.9 0.73 10.0 3.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 ORZ00241.1 - 0.38 10.8 7.5 0.55 10.3 5.1 2.4 2 1 0 2 2 2 0 Zinc-finger zf-RING_4 PF14570.6 ORZ00241.1 - 1.2 9.0 6.9 0.22 11.3 3.3 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Glyco_transf_22 PF03901.17 ORZ00242.1 - 2.1e-88 297.4 18.8 2.5e-88 297.1 18.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Myosin_head PF00063.21 ORZ00243.1 - 1.5e-277 922.3 0.0 3e-277 921.3 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 ORZ00243.1 - 7.8e-10 38.4 0.3 1.6e-09 37.5 0.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Fib_alpha PF08702.10 ORZ00243.1 - 0.003 17.7 6.4 0.003 17.7 6.4 4.4 2 1 1 4 4 4 1 Fibrinogen alpha/beta chain family IQ PF00612.27 ORZ00243.1 - 0.025 14.3 1.5 0.44 10.5 0.2 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4537 PF15057.6 ORZ00243.1 - 0.098 12.7 4.9 0.32 11.0 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4537) AAA_22 PF13401.6 ORZ00243.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ORZ00243.1 - 0.43 10.9 0.0 0.43 10.9 0.0 4.0 3 2 0 3 3 3 0 AAA ATPase domain PRK PF00485.18 ORZ00243.1 - 0.82 9.4 4.3 4.8 6.9 0.2 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family DUF812 PF05667.11 ORZ00243.1 - 1.8 7.4 51.0 0.064 12.1 44.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) NPV_P10 PF05531.12 ORZ00243.1 - 2 8.9 22.9 4.2 7.9 2.7 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein WWE PF02825.20 ORZ00246.1 - 0.00078 20.0 0.1 0.024 15.2 0.0 2.4 2 0 0 2 2 2 1 WWE domain Abhydrolase_3 PF07859.13 ORZ00247.1 - 1.8e-34 119.5 0.0 8.6e-26 91.1 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORZ00247.1 - 4.9e-08 32.2 0.0 6.6e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORZ00247.1 - 0.0088 15.5 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORZ00247.1 - 0.041 13.7 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ORZ00248.1 - 0.0043 16.9 0.0 0.0055 16.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORZ00248.1 - 0.024 13.5 0.0 0.024 13.5 0.0 1.0 1 0 0 1 1 1 0 Steryl acetyl hydrolase COesterase PF00135.28 ORZ00248.1 - 0.024 13.5 0.0 0.024 13.5 0.0 1.0 1 0 0 1 1 1 0 Carboxylesterase family Chlorophyllase2 PF12740.7 ORZ00248.1 - 0.1 11.5 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Chlorophyllase enzyme Proteasome PF00227.26 ORZ00250.1 - 4.3e-58 195.9 0.1 5.3e-58 195.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORZ00250.1 - 7.5e-14 51.1 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Asparaginase PF00710.20 ORZ00251.1 - 3.9e-61 205.9 0.0 6.5e-61 205.2 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORZ00251.1 - 1.2e-30 106.0 0.0 3.1e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 ORZ00251.1 - 1.5e-18 66.9 3.7 1.5e-07 31.9 0.1 4.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORZ00251.1 - 4.2e-17 62.5 0.0 4.1e-11 43.3 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORZ00251.1 - 2.9e-16 59.3 0.5 6.9e-10 39.0 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORZ00251.1 - 6.5e-10 39.0 3.3 6.5e-06 26.4 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORZ00251.1 - 1.3e-08 34.4 5.4 7.7e-06 25.9 0.1 4.5 5 0 0 5 5 5 2 Ankyrin repeat zf-DNL PF05180.12 ORZ00251.1 - 0.07 13.1 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 DNL zinc finger DDT PF02791.17 ORZ00252.1 - 7.7e-05 22.9 0.1 0.0002 21.6 0.1 1.6 1 0 0 1 1 1 1 DDT domain THB PF18362.1 ORZ00252.1 - 0.084 12.5 0.3 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Tri-helix bundle domain Peptidase_M19 PF01244.21 ORZ00252.1 - 0.36 9.9 2.2 0.6 9.2 2.2 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DUF2207 PF09972.9 ORZ00252.1 - 1.4 7.6 8.4 0.25 10.1 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CAF1 PF04857.20 ORZ00252.1 - 4.1 6.5 6.5 1.4 8.0 1.0 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease S1FA PF04689.13 ORZ00253.1 - 0.22 11.7 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Dus PF01207.17 ORZ00254.1 - 2.3e-72 243.7 0.0 2.7e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 ORZ00254.1 - 0.0036 16.6 0.0 1.3 8.2 0.0 2.1 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 ORZ00254.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 ORZ00254.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 ORZ00254.1 - 0.054 13.0 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein Sel1 PF08238.12 ORZ00255.1 - 2e-117 381.0 105.8 2.2e-07 31.3 1.2 30.8 33 0 0 33 33 33 24 Sel1 repeat TPR_8 PF13181.6 ORZ00255.1 - 0.02 15.1 11.3 24 5.5 0.1 9.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00255.1 - 0.052 14.2 0.2 0.032 14.9 4.9 16.9 15 4 5 20 20 20 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ00255.1 - 0.11 13.1 0.1 0.11 13.1 0.1 10.6 9 1 0 10 10 10 0 Tetratricopeptide repeat SOCS PF12610.8 ORZ00255.1 - 2.1 8.8 4.0 1.2 9.6 1.0 2.2 2 0 0 2 2 2 0 Suppressor of cytokine signalling TPR_11 PF13414.6 ORZ00255.1 - 8.4 6.2 30.6 6.5 6.5 0.1 11.8 13 1 1 14 14 14 0 TPR repeat THF_DHG_CYH PF00763.23 ORZ00256.1 - 4.7e-26 91.3 0.1 9.4e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 ORZ00256.1 - 2.4e-13 49.7 0.1 4.7e-11 42.3 0.1 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FrpC PF06901.12 ORZ00256.1 - 0.016 14.8 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC UDPG_MGDP_dh_N PF03721.14 ORZ00256.1 - 0.021 14.4 0.3 1.5 8.4 0.1 2.9 2 2 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DpaA_N PF16924.5 ORZ00256.1 - 0.03 14.4 0.0 0.6 10.2 0.0 2.5 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain RXLR PF16810.5 ORZ00256.1 - 0.046 14.1 0.1 0.089 13.2 0.1 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity SH3_9 PF14604.6 ORZ00257.1 - 5e-44 147.9 4.1 1.2e-15 57.1 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 ORZ00257.1 - 9e-37 124.5 3.0 8.7e-13 47.7 0.1 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 ORZ00257.1 - 3.4e-35 119.5 0.1 3.8e-10 39.3 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_10 PF17902.1 ORZ00257.1 - 0.0028 17.7 0.0 0.32 11.1 0.0 2.6 2 0 0 2 2 2 1 SH3 domain DUF3298 PF11738.8 ORZ00257.1 - 6.1 8.0 5.7 1.6 9.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) PilJ PF13675.6 ORZ00258.1 - 0.018 15.1 3.5 0.022 14.8 1.2 2.4 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF948 PF06103.11 ORZ00258.1 - 0.065 13.5 3.4 16 5.8 0.1 3.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Efg1 PF10153.9 ORZ00258.1 - 0.12 12.7 4.5 0.12 12.7 2.0 2.2 1 1 0 2 2 2 0 rRNA-processing protein Efg1 MLD PF11647.8 ORZ00258.1 - 0.18 12.1 1.3 0.65 10.3 0.1 2.6 3 0 0 3 3 3 0 Membrane Localization Domain HN PF00423.19 ORZ00258.1 - 1.4 7.6 4.6 0.26 10.0 1.2 1.4 2 0 0 2 2 2 0 Haemagglutinin-neuraminidase RNase_H2-Ydr279 PF09468.10 ORZ00259.1 - 2.8e-13 50.3 1.1 5.9e-13 49.3 1.1 1.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 ORZ00259.1 - 1.1e-06 28.7 0.0 3.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain ADPrib_exo_Tox PF03496.14 ORZ00259.1 - 0.0043 16.4 0.1 0.007 15.7 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Vpu PF00558.19 ORZ00259.1 - 0.065 13.0 0.1 3.4 7.5 0.2 2.5 2 0 0 2 2 2 0 Vpu protein Mpv17_PMP22 PF04117.12 ORZ00260.1 - 1.7e-08 34.5 3.4 2.7e-08 33.9 2.5 1.8 1 1 0 1 1 1 1 Mpv17 / PMP22 family HEAT PF02985.22 ORZ00261.1 - 9.3e-11 41.0 8.6 0.39 11.1 0.1 7.6 8 0 0 8 8 7 4 HEAT repeat HEAT_2 PF13646.6 ORZ00261.1 - 2.9e-07 30.8 4.6 0.0021 18.4 0.0 5.9 4 2 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 ORZ00261.1 - 0.00015 22.2 6.6 4 8.1 0.0 6.3 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 ORZ00261.1 - 0.00087 19.4 8.1 0.046 13.8 0.2 4.4 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 ORZ00261.1 - 0.0018 16.9 8.5 0.016 13.7 0.0 3.5 4 0 0 4 4 4 2 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 ORZ00261.1 - 0.0063 16.7 5.2 1.8 8.8 0.0 4.6 3 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 ORZ00261.1 - 0.0082 16.4 11.5 0.85 10.0 0.1 4.9 6 0 0 6 6 6 2 HEAT repeat associated with sister chromatid cohesion RICTOR_M PF14666.6 ORZ00261.1 - 0.025 14.3 0.3 0.37 10.6 0.0 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Npa1 PF11707.8 ORZ00261.1 - 0.11 11.8 2.1 8.7 5.6 0.1 3.2 2 1 1 3 3 3 0 Ribosome 60S biogenesis N-terminal DUF3517 PF12030.8 ORZ00261.1 - 0.12 11.3 1.8 0.77 8.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3517) RasGEF_N_2 PF14663.6 ORZ00261.1 - 1.5 9.2 4.3 3.1 8.3 0.1 3.5 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain AAA PF00004.29 ORZ00262.1 - 6.8e-98 324.2 0.0 3.3e-48 163.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ00262.1 - 5.5e-29 99.7 5.1 3.3e-14 52.4 0.3 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 ORZ00262.1 - 7.6e-18 64.5 0.8 2.2e-17 63.0 0.8 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ORZ00262.1 - 2.3e-14 53.4 0.0 8.8e-06 25.5 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORZ00262.1 - 2.6e-13 50.4 0.0 3e-07 30.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 ORZ00262.1 - 4.6e-13 48.8 0.0 9.9e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 ORZ00262.1 - 4.3e-12 46.4 0.0 7.1e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORZ00262.1 - 5.1e-12 46.0 0.2 2.3e-05 24.4 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORZ00262.1 - 1.7e-11 44.8 0.0 0.0012 19.2 0.0 4.3 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 ORZ00262.1 - 2.4e-09 37.6 0.1 0.021 15.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORZ00262.1 - 2.5e-09 36.8 1.2 0.00082 18.7 0.1 2.8 3 1 0 3 3 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 ORZ00262.1 - 4.2e-08 32.8 0.2 0.004 16.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORZ00262.1 - 6.5e-08 33.2 0.0 0.011 16.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 ORZ00262.1 - 5.7e-07 29.4 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 ORZ00262.1 - 7.2e-07 29.6 0.0 0.018 15.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Parvo_NS1 PF01057.17 ORZ00262.1 - 7.8e-07 28.5 0.1 0.0057 15.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 ORZ00262.1 - 1.2e-06 28.2 0.8 0.37 10.4 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_7 PF12775.7 ORZ00262.1 - 1.9e-06 27.5 0.0 0.012 15.2 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 ORZ00262.1 - 2e-06 27.9 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ORZ00262.1 - 3.2e-06 27.7 0.0 0.026 15.0 0.0 3.7 3 1 0 3 3 2 1 ABC transporter AAA_28 PF13521.6 ORZ00262.1 - 3.3e-06 27.4 0.0 0.079 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 ORZ00262.1 - 4.6e-06 26.4 0.1 0.19 11.4 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 ORZ00262.1 - 5e-06 26.4 0.0 0.14 11.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain Vps4_C PF09336.10 ORZ00262.1 - 8.7e-06 25.7 0.1 0.00024 21.0 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.18 ORZ00262.1 - 1.1e-05 25.4 0.0 0.06 13.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein ATPase PF06745.13 ORZ00262.1 - 2.6e-05 23.7 0.3 1.6 8.0 0.0 3.4 3 0 0 3 3 3 2 KaiC DUF815 PF05673.13 ORZ00262.1 - 6.3e-05 22.3 0.0 0.033 13.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 ORZ00262.1 - 9.8e-05 22.4 0.1 0.087 12.8 0.0 2.7 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 ORZ00262.1 - 0.0001 22.3 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 ORZ00262.1 - 0.00016 21.5 0.0 0.64 9.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORZ00262.1 - 0.00017 22.1 1.4 0.54 10.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_11 PF13086.6 ORZ00262.1 - 0.00018 21.4 0.1 0.9 9.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 ORZ00262.1 - 0.00024 21.0 0.1 0.15 12.0 0.0 3.1 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.9 ORZ00262.1 - 0.00025 20.4 0.0 0.43 9.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 ORZ00262.1 - 0.00027 20.5 1.3 0.75 9.2 0.0 2.9 3 0 0 3 3 3 2 PhoH-like protein ATPase_2 PF01637.18 ORZ00262.1 - 0.00034 20.6 0.2 2.2 8.1 0.1 3.3 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 ORZ00262.1 - 0.00077 18.8 0.0 1.3 8.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin SRPRB PF09439.10 ORZ00262.1 - 0.00089 18.7 0.7 4 6.8 0.3 4.2 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 ORZ00262.1 - 0.0012 19.1 1.3 2.2 8.6 0.0 3.6 3 1 1 4 4 3 1 AAA domain NB-ARC PF00931.22 ORZ00262.1 - 0.0012 18.0 0.0 0.5 9.5 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 ORZ00262.1 - 0.0015 18.3 0.3 1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ORZ00262.1 - 0.0044 16.8 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 ORZ00262.1 - 0.0091 15.8 0.0 4.7 6.9 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 ORZ00262.1 - 0.0098 16.0 0.0 6.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 ORZ00262.1 - 0.014 15.3 0.6 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 NTPase T2SSE PF00437.20 ORZ00262.1 - 0.024 13.7 0.0 0.89 8.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 ORZ00262.1 - 0.067 12.6 0.1 6 6.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase TniB PF05621.11 ORZ00262.1 - 0.076 12.4 0.1 17 4.7 0.0 2.8 3 0 0 3 3 2 0 Bacterial TniB protein Zot PF05707.12 ORZ00262.1 - 0.079 12.6 0.0 2.6 7.6 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Hydin_ADK PF17213.3 ORZ00262.1 - 0.081 13.2 2.2 43 4.3 0.0 3.9 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain AFG1_ATPase PF03969.16 ORZ00262.1 - 0.087 11.7 0.0 8.8 5.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase PIF1 PF05970.14 ORZ00262.1 - 0.14 11.3 0.0 5.6 6.0 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase AAA_23 PF13476.6 ORZ00262.1 - 0.18 12.3 0.3 9.4 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_6 PF12774.7 ORZ00262.1 - 0.24 10.4 0.3 13 4.6 0.0 2.6 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region Forkhead PF00250.18 ORZ00264.1 - 6e-33 113.0 0.1 9.5e-33 112.3 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain 2OG-FeII_Oxy_3 PF13640.6 ORZ00265.1 - 8.4e-10 39.4 0.1 1.4e-09 38.7 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 ORZ00265.1 - 0.00078 19.9 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 ORZ00265.1 - 0.0099 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein Adaptin_N PF01602.20 ORZ00266.1 - 2.7e-119 399.1 3.5 3.9e-119 398.6 3.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORZ00266.1 - 4.8e-15 56.0 0.2 8.9e-12 45.3 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORZ00266.1 - 1.6e-05 24.7 1.7 1.8 9.0 0.0 5.3 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 ORZ00266.1 - 9.9e-05 22.7 1.9 0.79 10.1 0.0 4.3 4 1 1 5 5 5 3 HEAT repeats AP3D1 PF06375.11 ORZ00266.1 - 0.0011 19.3 0.2 0.0011 19.3 0.2 4.4 1 1 2 3 3 3 1 AP-3 complex subunit delta-1 WD40 PF00400.32 ORZ00267.1 - 1.1e-32 111.5 3.2 1.8e-06 28.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00267.1 - 3.1e-17 62.7 0.0 0.005 17.1 0.0 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ00267.1 - 5.3e-06 26.5 0.0 0.00039 20.4 0.0 3.1 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A CSTF1_dimer PF16699.5 ORZ00267.1 - 8.6e-06 25.4 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Ge1_WD40 PF16529.5 ORZ00267.1 - 0.0034 16.4 0.2 2.7 6.8 0.0 3.3 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORZ00267.1 - 0.011 14.4 0.0 4.4 5.8 0.0 3.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 ORZ00267.1 - 0.018 15.1 0.0 0.64 10.1 0.0 3.4 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region DUF2183 PF09949.9 ORZ00267.1 - 0.057 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) DUF202 PF02656.15 ORZ00268.1 - 2.2e-13 50.5 0.1 2.2e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SLC3A2_N PF16028.5 ORZ00268.1 - 3.8 7.1 5.7 3.2 7.4 0.1 2.4 1 1 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus RabGAP-TBC PF00566.18 ORZ00269.1 - 1.8e-57 194.4 0.1 3e-57 193.7 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.17 ORZ00269.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Trp_syntA PF00290.20 ORZ00269.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DUF4259 PF14078.6 ORZ00270.1 - 0.14 12.9 0.8 0.25 12.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Zn_clus PF00172.18 ORZ00271.1 - 2.3e-07 30.8 8.3 4.6e-07 29.8 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NARP1 PF12569.8 ORZ00271.1 - 0.072 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 ORZ00271.1 - 0.15 12.3 0.3 0.52 10.5 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat MSA-2c PF12238.8 ORZ00271.1 - 0.17 11.9 3.1 0.33 10.9 3.1 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c SKA1 PF07160.12 ORZ00271.1 - 0.49 10.2 2.3 0.91 9.3 2.3 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CAF1A PF12253.8 ORZ00272.1 - 6.7e-25 87.1 5.0 6.7e-25 87.1 5.0 2.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Eapp_C PF10238.9 ORZ00272.1 - 0.76 9.8 5.5 1.7 8.7 5.5 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein CAF-1_p150 PF11600.8 ORZ00272.1 - 1.1 8.9 42.0 0.035 13.8 35.1 2.2 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AMP-binding PF00501.28 ORZ00273.1 - 1.5e-39 135.8 0.0 2.4e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORZ00273.1 - 1.6e-34 119.2 0.0 3.5e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ORZ00273.1 - 8.2e-11 42.1 0.0 1.8e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORZ00273.1 - 0.00014 21.4 0.0 0.00034 20.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORZ00273.1 - 0.047 12.8 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 ORZ00273.1 - 0.077 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 KR domain TRP PF06011.12 ORZ00278.1 - 1.7e-12 46.8 1.0 2.5e-11 43.0 1.0 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 ORZ00278.1 - 0.0037 17.7 0.2 0.0054 17.2 0.2 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 ORZ00278.1 - 0.0055 17.1 0.8 0.0099 16.3 0.8 1.3 1 0 0 1 1 1 1 ML-like domain TRP PF06011.12 ORZ00279.1 - 1.7e-13 50.1 3.2 1.8e-13 50.0 3.2 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF2079 PF09852.9 ORZ00279.1 - 0.022 13.6 2.4 0.026 13.4 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF2124 PF09897.9 ORZ00279.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Amidohydro_1 PF01979.20 ORZ00280.1 - 3.3e-20 72.7 1.7 6.5e-19 68.4 1.7 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORZ00280.1 - 8.1e-14 51.9 0.5 2.3e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family NRDE-2 PF08424.10 ORZ00282.1 - 2e-95 319.6 19.2 4.1e-95 318.6 3.0 3.6 2 1 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 ORZ00282.1 - 2.3e-09 37.3 15.6 0.13 13.1 0.0 8.6 8 2 2 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ00282.1 - 2.7e-07 31.0 5.6 0.012 16.1 0.5 5.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ00282.1 - 7.7e-05 22.8 1.1 1.1 9.8 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ00282.1 - 0.0002 21.6 3.5 0.00062 20.0 0.0 3.6 4 1 1 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORZ00282.1 - 0.00025 21.0 3.9 0.76 9.8 0.2 5.3 5 0 0 5 5 5 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 ORZ00282.1 - 0.001 18.4 11.1 0.85 8.8 0.0 4.8 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00282.1 - 0.0017 19.0 0.9 0.028 15.1 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ00282.1 - 0.0034 17.4 10.4 0.045 13.9 0.2 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ00282.1 - 0.082 13.2 4.0 0.55 10.6 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Presenilin PF01080.17 ORZ00282.1 - 0.31 9.8 2.5 0.49 9.1 2.5 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 ORZ00282.1 - 1.3 7.7 6.0 2.4 6.8 6.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TPR_11 PF13414.6 ORZ00282.1 - 1.5 8.6 5.0 25 4.6 0.1 3.4 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.28 ORZ00282.1 - 2 8.4 9.0 22 5.1 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Apt1 PF10351.9 ORZ00282.1 - 2.5 6.9 8.4 5.1 5.8 8.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ras PF00071.22 ORZ00283.1 - 4.7e-59 198.6 0.1 5.9e-59 198.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ00283.1 - 8.5e-22 77.6 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ00283.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORZ00283.1 - 0.001 19.0 0.1 0.63 9.9 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORZ00283.1 - 0.0016 18.0 0.1 0.004 16.7 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORZ00283.1 - 0.0038 17.3 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 ORZ00283.1 - 0.17 11.6 0.6 1.9 8.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Inhibitor_I36 PF03995.13 ORZ00284.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor family I36 DUF5323 PF17257.2 ORZ00284.1 - 0.096 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5323) AMP-binding PF00501.28 ORZ00285.1 - 7.6e-44 150.0 0.0 1.2e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORZ00285.1 - 5.6e-34 117.5 0.0 1.7e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 ORZ00285.1 - 4.3e-09 36.6 0.2 9.7e-09 35.5 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORZ00285.1 - 0.00013 21.5 0.0 0.00058 19.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORZ00285.1 - 0.068 12.3 0.0 0.18 10.9 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4999 PF16390.5 ORZ00285.1 - 0.071 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Mito_carr PF00153.27 ORZ00287.1 - 8.6e-61 201.9 4.2 2.9e-21 75.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 ORZ00287.1 - 0.068 13.5 0.6 0.29 11.5 0.6 2.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF4329 PF14220.6 ORZ00287.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) NUDIX PF00293.28 ORZ00288.1 - 9.6e-08 32.1 0.0 8.9e-06 25.8 0.0 2.6 1 1 0 1 1 1 1 NUDIX domain COX7C PF02935.16 ORZ00290.1 - 2.5e-17 62.9 1.0 3e-17 62.6 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Adeno_E3_CR2 PF02439.15 ORZ00291.1 - 1.1e-05 25.0 2.4 2e-05 24.3 2.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Kelch_6 PF13964.6 ORZ00291.1 - 0.00068 19.8 0.0 6.3 7.2 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Herpes_gE PF02480.16 ORZ00291.1 - 0.0024 16.7 0.0 0.0035 16.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 ORZ00291.1 - 0.0028 18.5 0.0 0.0053 17.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 ORZ00291.1 - 0.0031 17.1 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Mid2 PF04478.12 ORZ00291.1 - 0.0036 17.1 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Kelch_5 PF13854.6 ORZ00291.1 - 0.0037 17.2 0.1 3.1 7.9 0.0 3.6 3 0 0 3 3 3 1 Kelch motif CbtA PF09490.10 ORZ00291.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) DUF4051 PF13260.6 ORZ00291.1 - 0.0062 16.2 1.0 0.013 15.2 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4051) DUF4381 PF14316.6 ORZ00291.1 - 0.035 14.4 0.2 0.069 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 ORZ00291.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM65 PF10507.9 ORZ00291.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 65 Tweety PF04906.13 ORZ00291.1 - 0.27 9.8 0.2 0.42 9.2 0.2 1.2 1 0 0 1 1 1 0 Tweety NAT PF04768.13 ORZ00292.1 - 1.7e-37 128.7 0.1 4.6e-37 127.3 0.0 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 ORZ00292.1 - 4.8e-32 111.5 0.2 2.1e-31 109.4 0.1 1.9 1 1 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 ORZ00292.1 - 1.1e-29 103.3 0.0 3e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORZ00292.1 - 0.0025 17.9 0.3 0.017 15.2 0.0 2.8 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 ORZ00292.1 - 0.007 17.2 0.0 0.021 15.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF5476 PF17570.2 ORZ00292.1 - 0.17 12.3 0.2 0.42 11.0 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5476) SPX PF03105.19 ORZ00293.1 - 6.8 6.5 11.0 13 5.5 11.0 1.5 1 0 0 1 1 1 0 SPX domain tRNA-synt_His PF13393.6 ORZ00294.1 - 2.7e-44 151.7 0.0 3.5e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ORZ00294.1 - 3.5e-10 39.9 0.0 6.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORZ00294.1 - 0.00019 21.5 0.0 0.0062 16.5 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 ORZ00294.1 - 0.0045 16.1 0.2 0.058 12.5 0.4 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) RRM_1 PF00076.22 ORZ00295.1 - 1.3e-37 127.4 0.0 1.4e-18 66.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORZ00295.1 - 2.7e-08 33.5 0.0 5.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 ORZ00295.1 - 9.8e-05 21.9 0.3 0.26 11.0 0.0 2.8 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 ORZ00295.1 - 0.026 14.7 0.1 0.13 12.4 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 ORZ00295.1 - 0.047 13.7 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORZ00295.1 - 0.053 13.6 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif ADIP PF11559.8 ORZ00296.1 - 0.0078 16.3 8.0 0.0078 16.3 8.0 2.3 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Activator_LAG-3 PF11498.8 ORZ00296.1 - 0.015 14.3 22.0 0.02 13.9 22.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CENP-F_leu_zip PF10473.9 ORZ00296.1 - 0.069 13.2 16.1 0.16 12.0 16.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TRAF_BIRC3_bd PF16673.5 ORZ00296.1 - 0.2 11.5 0.3 0.2 11.5 0.3 2.7 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain ACR_tran PF00873.19 ORZ00296.1 - 0.58 7.7 6.9 0.64 7.6 6.9 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Jnk-SapK_ap_N PF09744.9 ORZ00296.1 - 1 9.6 17.6 1.6 9.0 17.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CAP_GLY PF01302.25 ORZ00297.1 - 2.7e-20 72.1 0.0 4.2e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 ORZ00297.1 - 9.1e-07 28.6 17.0 8.6e-06 25.5 5.1 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle BTB PF00651.31 ORZ00298.1 - 1.7e-07 31.4 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3408 PF11888.8 ORZ00298.1 - 0.84 9.8 5.2 13 5.9 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) TERB2 PF15101.6 ORZ00298.1 - 7.3 6.6 9.0 3.8 7.5 5.0 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PPR_2 PF13041.6 ORZ00299.1 - 8.7e-29 99.5 0.6 3.4e-06 27.2 0.0 9.4 7 1 2 9 9 9 7 PPR repeat family PPR_3 PF13812.6 ORZ00299.1 - 6.8e-26 90.1 3.3 1.2e-06 28.5 0.0 7.9 5 2 3 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.20 ORZ00299.1 - 8.1e-21 72.8 1.8 0.002 18.2 0.0 9.4 10 0 0 10 10 9 4 PPR repeat PPR_long PF17177.4 ORZ00299.1 - 3.7e-20 72.2 0.6 0.00018 21.0 0.0 5.4 4 2 2 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORZ00299.1 - 1e-14 53.9 0.2 0.018 14.7 0.0 6.7 8 0 0 8 8 8 3 PPR repeat ATP13 PF12921.7 ORZ00299.1 - 2.8e-05 24.0 0.2 1.5 8.7 0.0 5.2 5 1 0 5 5 5 1 Mitochondrial ATPase expression TPR_19 PF14559.6 ORZ00299.1 - 0.00041 20.8 1.7 0.21 12.1 0.0 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat SPO22 PF08631.10 ORZ00299.1 - 0.0056 16.2 1.0 0.1 12.1 0.3 2.9 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Wzy_C_2 PF11846.8 ORZ00299.1 - 0.015 15.2 0.5 18 5.2 0.0 3.8 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Clathrin PF00637.20 ORZ00299.1 - 0.11 12.4 0.4 5.2 6.9 0.0 3.6 4 0 0 4 4 4 0 Region in Clathrin and VPS Phage_term_smal PF05944.12 ORZ00299.1 - 0.15 12.0 3.9 8.9 6.3 0.3 3.4 3 0 0 3 3 3 0 Phage small terminase subunit DUF2989 PF11207.8 ORZ00299.1 - 1.3 8.7 5.3 0.64 9.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2989) CorA PF01544.18 ORZ00300.1 - 2.1e-53 181.6 0.6 3e-53 181.0 0.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Allantoicase PF03561.15 ORZ00301.1 - 3.2e-82 273.6 0.0 1e-43 148.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat PDEase_I PF00233.19 ORZ00302.1 - 8.7e-70 235.1 0.5 6.7e-69 232.2 0.5 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 ORZ00302.1 - 5.2e-07 29.8 0.0 5.8e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain AIM5 PF17050.5 ORZ00303.1 - 0.0024 18.7 0.0 0.0034 18.2 0.0 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DUF1320 PF07030.12 ORZ00303.1 - 0.038 14.1 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Septin PF00735.18 ORZ00304.1 - 4.8e-14 52.3 0.0 9.3e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORZ00304.1 - 0.0065 16.5 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORZ00304.1 - 0.013 15.9 0.1 0.013 15.9 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORZ00304.1 - 0.029 14.7 0.3 0.099 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain TarH PF02203.15 ORZ00304.1 - 0.038 13.9 0.5 0.084 12.8 0.5 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue AAA_24 PF13479.6 ORZ00304.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Myc_N PF01056.18 ORZ00304.1 - 0.12 12.3 3.7 0.23 11.3 3.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region zf-C2H2 PF00096.26 ORZ00305.1 - 6.2e-17 61.0 50.2 0.00071 19.9 3.0 7.8 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ00305.1 - 2.2e-11 43.6 47.7 0.089 13.7 1.1 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ00305.1 - 2.6e-10 40.8 22.5 0.5 11.0 0.0 7.3 4 2 3 7 7 7 6 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 ORZ00305.1 - 0.016 15.0 1.6 0.016 15.0 1.6 7.2 9 0 0 9 9 9 0 C2H2-type zinc-finger domain SERTA PF06031.13 ORZ00306.1 - 5.1e-05 22.8 0.1 8.1e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 SERTA motif CAP_N PF01213.19 ORZ00306.1 - 0.0044 16.6 6.2 0.0053 16.3 6.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 ORZ00306.1 - 0.018 15.1 3.0 0.018 15.1 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 ORZ00306.1 - 0.037 14.0 6.6 0.054 13.5 6.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SMC_N PF02463.19 ORZ00307.1 - 4.5e-63 212.6 0.2 8.7e-63 211.7 0.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORZ00307.1 - 2.7e-19 69.6 0.0 2.7e-18 66.3 0.0 2.6 1 1 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 ORZ00307.1 - 4.1e-15 56.4 0.4 4.1e-15 56.4 0.4 4.0 2 2 2 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 ORZ00307.1 - 1e-11 45.2 13.3 4.4e-06 26.7 0.1 4.1 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORZ00307.1 - 0.00036 21.1 52.4 0.00036 21.1 52.4 6.2 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 ORZ00307.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ORZ00307.1 - 0.46 11.0 0.0 0.46 11.0 0.0 6.8 3 2 1 4 4 4 0 ABC transporter PatG_C PF18065.1 ORZ00307.1 - 0.62 10.1 4.3 1.7 8.6 0.4 3.0 2 0 0 2 2 2 0 PatG C-terminal CENP-N PF05238.13 ORZ00308.1 - 9e-19 68.1 0.5 2.1e-18 66.9 0.5 1.5 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Glutaredoxin PF00462.24 ORZ00309.1 - 5.4e-19 68.2 0.0 7.5e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 ORZ00309.1 - 0.055 13.9 0.2 0.18 12.3 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 ORZ00309.1 - 0.059 13.8 0.0 0.096 13.1 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 ORZ00309.1 - 0.063 13.4 0.5 6.1 7.0 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DUF2015 PF09435.10 ORZ00310.1 - 3.1e-33 114.0 0.0 3.6e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) PrmA PF06325.13 ORZ00311.1 - 1.3e-14 54.3 0.1 2.7e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORZ00311.1 - 2.2e-12 47.0 0.1 1.1e-11 44.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ00311.1 - 3.4e-12 46.9 0.0 9.4e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ00311.1 - 2e-10 41.2 0.0 5.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ00311.1 - 2.4e-08 33.7 0.2 5.1e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 ORZ00311.1 - 1.6e-07 31.4 0.1 2.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORZ00311.1 - 2.6e-06 27.0 0.1 4.6e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 ORZ00311.1 - 9.3e-06 26.3 0.1 4.9e-05 24.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.16 ORZ00311.1 - 2.4e-05 24.2 2.9 0.00012 21.9 3.0 1.9 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 ORZ00311.1 - 3e-05 23.9 0.0 8.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 ORZ00311.1 - 3.2e-05 23.8 1.9 6.6e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 ORZ00311.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORZ00311.1 - 0.00046 19.2 0.1 0.00078 18.5 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 ORZ00311.1 - 0.0013 18.5 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 ORZ00311.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 ORZ00311.1 - 0.002 17.8 0.1 0.0047 16.6 0.1 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 ORZ00311.1 - 0.0045 16.3 0.1 0.0094 15.3 0.1 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 ORZ00311.1 - 0.0059 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 ORZ00311.1 - 0.0067 17.4 0.0 0.035 15.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain zf-C2H2_2 PF12756.7 ORZ00311.1 - 0.0087 16.4 0.2 0.024 15.0 0.2 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_32 PF13679.6 ORZ00311.1 - 0.046 13.7 0.3 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RGS PF00615.19 ORZ00311.1 - 0.046 14.0 2.8 2.4 8.5 0.0 2.8 2 1 0 2 2 2 0 Regulator of G protein signaling domain Cep57_CLD PF14073.6 ORZ00311.1 - 0.081 12.9 1.0 0.14 12.2 1.0 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Lipase_GDSL PF00657.22 ORZ00312.1 - 2e-11 44.3 0.2 2.7e-11 43.8 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORZ00312.1 - 0.00016 22.2 0.1 0.0042 17.5 0.1 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DXP_synthase_N PF13292.6 ORZ00312.1 - 0.19 10.9 0.1 0.34 10.1 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Ribosomal_S21e PF01249.18 ORZ00313.1 - 8e-40 134.8 0.0 8.9e-40 134.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e RHS_repeat PF05593.14 ORZ00313.1 - 0.25 11.9 1.8 4.1 8.0 0.0 3.1 4 0 0 4 4 4 0 RHS Repeat DUF1765 PF08578.10 ORZ00315.1 - 1.4e-18 67.6 0.7 1.4e-18 67.6 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) AMP-binding PF00501.28 ORZ00316.1 - 7.4e-86 288.4 0.0 9.4e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ00316.1 - 3.3e-14 53.6 0.2 9.8e-14 52.1 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4035 PF13227.6 ORZ00316.1 - 0.032 13.9 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Maf PF02545.14 ORZ00317.1 - 6e-51 172.6 0.0 6.8e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein SMAP PF15477.6 ORZ00317.1 - 0.12 13.4 0.0 0.18 12.8 0.0 1.4 1 0 0 1 1 1 0 Small acidic protein family zf-C2H2 PF00096.26 ORZ00318.1 - 1.5e-09 37.8 21.9 0.00017 21.8 0.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ00318.1 - 1e-05 25.7 25.7 6e-05 23.3 1.1 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORZ00318.1 - 0.00021 21.6 4.4 0.012 15.8 4.6 2.6 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 ORZ00318.1 - 0.0018 18.9 20.8 0.064 14.1 0.1 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ00318.1 - 0.11 13.2 14.5 1.3 9.7 0.1 4.4 3 2 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORZ00318.1 - 0.51 10.5 10.8 10 6.2 0.0 4.2 3 1 2 5 5 5 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 ORZ00318.1 - 3 8.0 11.2 0.93 9.6 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger MWFE PF15879.5 ORZ00319.1 - 6e-26 90.4 0.2 7.4e-26 90.1 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit WD40 PF00400.32 ORZ00320.1 - 2.6e-40 135.7 25.0 3.6e-06 27.6 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00320.1 - 7.4e-14 51.8 0.4 0.068 13.5 0.0 5.9 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 ORZ00320.1 - 5.9e-12 45.3 1.0 1.1e-11 44.4 1.0 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 ORZ00320.1 - 7.2e-11 41.4 3.8 0.0083 14.8 0.1 5.4 2 2 4 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 ORZ00320.1 - 8.1e-09 35.2 0.0 5.9e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain DUF5046 PF16465.5 ORZ00320.1 - 1.1e-06 28.4 0.0 0.27 10.7 0.0 3.7 1 1 3 4 4 4 3 Domain of unknown function (DUF5046) F-box PF00646.33 ORZ00320.1 - 4.4e-05 23.2 0.2 8.8e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 ORZ00320.1 - 0.0018 17.9 0.2 0.56 9.7 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 ORZ00320.1 - 0.0019 18.6 0.3 6 7.5 0.0 5.1 5 1 0 6 6 6 1 PQQ-like domain Hira PF07569.11 ORZ00320.1 - 0.19 11.4 0.6 4 7.1 0.0 2.8 3 1 0 3 3 3 0 TUP1-like enhancer of split Sulfate_transp PF00916.20 ORZ00321.1 - 2.9e-94 316.0 16.8 3.9e-94 315.5 16.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORZ00321.1 - 2.8e-21 75.3 0.0 4.9e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORZ00321.1 - 7e-05 23.2 4.9 7e-05 23.2 4.9 2.8 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORZ00321.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 STAS domain Iso_dh PF00180.20 ORZ00322.1 - 2e-123 412.0 0.0 2.4e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.28 ORZ00323.1 - 3.4e-31 109.3 0.0 5.2e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORZ00323.1 - 8.2e-11 42.2 0.7 1.5e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF5095 PF17016.5 ORZ00323.1 - 0.43 10.2 3.0 0.64 9.7 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Kinesin PF00225.23 ORZ00324.1 - 8.8e-79 264.8 1.1 1e-78 264.6 1.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Dynactin PF12455.8 ORZ00325.1 - 6.5e-82 275.0 10.0 6.5e-82 275.0 10.0 4.0 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 ORZ00325.1 - 7.3e-25 86.8 0.4 1.2e-24 86.0 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain BST2 PF16716.5 ORZ00325.1 - 0.015 15.9 3.3 0.015 15.9 3.3 9.0 6 3 4 11 11 11 0 Bone marrow stromal antigen 2 Ank_2 PF12796.7 ORZ00326.1 - 0.046 14.3 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORZ00326.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Snapin_Pallidin PF14712.6 ORZ00327.1 - 1.5e-05 25.3 0.0 3.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Snapin/Pallidin FapA PF03961.13 ORZ00327.1 - 0.012 14.2 0.2 0.016 13.9 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BBP1_C PF15272.6 ORZ00327.1 - 0.24 11.2 5.4 0.48 10.2 5.4 1.5 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal UQ_con PF00179.26 ORZ00328.1 - 5.9e-41 139.4 0.1 7.7e-41 139.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORZ00328.1 - 0.019 15.3 0.3 0.024 14.9 0.3 1.4 1 1 0 1 1 1 0 RWD domain DUF4160 PF13711.6 ORZ00328.1 - 0.037 14.3 0.2 0.094 13.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) UEV PF05743.13 ORZ00328.1 - 0.067 13.1 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 ORZ00328.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B Histidinol_dh PF00815.20 ORZ00329.1 - 1.1e-161 538.4 0.6 1.9e-161 537.7 0.6 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 ORZ00329.1 - 7.1e-23 80.2 0.1 2.1e-22 78.7 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 ORZ00329.1 - 1.2e-15 57.7 1.5 3.1e-15 56.4 0.2 2.5 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 ORZ00329.1 - 0.072 13.4 0.3 0.16 12.3 0.3 1.5 1 0 0 1 1 1 0 MazG-like family MazG PF03819.17 ORZ00329.1 - 0.11 12.6 0.4 0.29 11.3 0.4 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Cu-oxidase_3 PF07732.15 ORZ00330.1 - 6.6e-32 110.0 1.5 1.4e-31 109.0 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ORZ00330.1 - 7.4e-28 97.7 0.0 5.6e-27 94.8 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORZ00330.1 - 3.8e-24 85.0 5.3 7.6e-20 71.0 0.9 3.3 3 1 0 3 3 3 2 Multicopper oxidase DUF2043 PF09740.9 ORZ00331.1 - 6.3e-30 104.0 0.7 2.1e-29 102.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) Secretin_N_2 PF07655.13 ORZ00331.1 - 0.026 15.1 0.7 0.093 13.3 0.5 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain CK_II_beta PF01214.18 ORZ00332.1 - 1.7e-58 197.4 0.0 2e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pkinase PF00069.25 ORZ00333.1 - 1.2e-49 169.1 0.0 1.5e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00333.1 - 1.2e-24 87.0 0.0 1.9e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORZ00333.1 - 0.0092 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORZ00333.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NTF2 PF02136.20 ORZ00334.1 - 1.1e-22 80.8 0.1 1.3e-22 80.7 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 ORZ00334.1 - 1.5e-12 47.7 0.0 1.9e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 GET2 PF08690.10 ORZ00335.1 - 0.052 13.2 0.2 0.052 13.2 0.2 2.4 1 1 1 2 2 2 0 GET complex subunit GET2 LNS2 PF08235.13 ORZ00337.1 - 6.9e-105 349.5 0.0 1e-104 349.0 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 ORZ00337.1 - 3.9e-41 139.1 0.0 7.6e-41 138.2 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 ORZ00337.1 - 4.1e-19 68.6 0.0 2.4e-18 66.1 0.0 2.3 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 ORZ00337.1 - 0.0002 22.1 0.7 0.0002 22.1 0.7 5.4 6 0 0 6 6 6 1 Putative WW-binding domain and destruction box WD40 PF00400.32 ORZ00338.1 - 6e-14 52.2 16.1 1.3e-05 25.8 0.1 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ECM1 PF05782.11 ORZ00338.1 - 1.1 8.1 3.9 0.6 9.0 0.2 2.0 2 0 0 2 2 2 0 Extracellular matrix protein 1 (ECM1) zf-U1 PF06220.12 ORZ00339.1 - 9.2e-22 76.5 3.9 1.2e-21 76.1 3.9 1.2 1 0 0 1 1 1 1 U1 zinc finger LUC7 PF03194.15 ORZ00339.1 - 0.14 11.8 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 LUC7 N_terminus LPD11 PF18824.1 ORZ00339.1 - 0.15 12.1 0.1 0.22 11.6 0.1 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 zf-C2H2_jaz PF12171.8 ORZ00339.1 - 9.5 6.6 10.2 1e+02 3.4 10.2 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_10 PF10058.9 ORZ00340.1 - 4.6e-16 58.3 0.1 7.8e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Myc_N PF01056.18 ORZ00340.1 - 0.3 10.9 9.6 0.033 14.1 2.9 2.0 2 0 0 2 2 2 0 Myc amino-terminal region SUIM_assoc PF16619.5 ORZ00340.1 - 0.51 10.4 26.1 0.19 11.8 7.0 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Zip PF02535.22 ORZ00340.1 - 2.1 7.5 3.4 4.4 6.4 0.8 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF913 PF06025.12 ORZ00340.1 - 3.1 6.7 9.2 0.25 10.3 1.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.14 ORZ00340.1 - 3.2 7.5 10.5 0.12 12.2 3.9 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PS_Dcarbxylase PF02666.15 ORZ00341.1 - 8.9e-71 237.6 0.0 1.7e-55 187.7 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 ORZ00341.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 MNLL subunit Ribosomal_L6e PF01159.19 ORZ00342.1 - 3.4e-33 114.5 0.8 3.4e-33 114.5 0.8 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e AAA_lid_10 PF17872.1 ORZ00342.1 - 0.0032 17.5 0.3 0.0058 16.7 0.3 1.4 1 0 0 1 1 1 1 AAA lid domain Na_Ca_ex PF01699.24 ORZ00343.1 - 3e-39 134.4 45.0 1.8e-24 86.4 16.5 3.3 4 0 0 4 4 4 2 Sodium/calcium exchanger protein Pkinase PF00069.25 ORZ00344.1 - 4.6e-63 213.1 0.0 7.4e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00344.1 - 1.6e-32 112.8 0.0 2.2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ00344.1 - 9.8e-08 31.6 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORZ00344.1 - 0.0006 18.7 0.0 0.0014 17.5 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORZ00344.1 - 0.0045 16.4 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORZ00344.1 - 0.016 15.2 0.2 0.025 14.5 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acyltransferase PF01553.21 ORZ00345.1 - 1.3e-35 122.0 0.0 1.8e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase PRANC PF09372.10 ORZ00345.1 - 0.097 13.0 0.5 0.74 10.2 0.1 2.1 2 0 0 2 2 2 0 PRANC domain Cyclin_N PF00134.23 ORZ00346.1 - 2.5e-14 53.1 0.1 4.4e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORZ00346.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF2183 PF09949.9 ORZ00348.1 - 4.3e-29 100.8 0.0 1.1e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 ORZ00348.1 - 0.039 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Coq4 PF05019.13 ORZ00349.1 - 1.1e-93 312.6 0.0 1.3e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PGK PF00162.19 ORZ00350.1 - 1.4e-148 494.9 2.3 1.6e-148 494.7 2.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase LMBR1 PF04791.16 ORZ00351.1 - 1.1e-116 390.8 20.0 1.3e-116 390.5 20.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein SUIM_assoc PF16619.5 ORZ00352.1 - 4.1 7.5 9.6 0.06 13.4 0.7 2.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cupin_8 PF13621.6 ORZ00353.1 - 9.4e-40 136.9 0.0 1.3e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORZ00353.1 - 1.7e-11 44.2 0.2 2.5e-11 43.6 0.2 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 ORZ00353.1 - 5.4e-05 23.6 0.5 0.00044 20.7 0.0 2.6 3 1 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 ORZ00353.1 - 0.034 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain LRR_8 PF13855.6 ORZ00354.1 - 4e-23 80.9 17.6 2.6e-09 36.7 3.4 5.1 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORZ00354.1 - 1.1e-21 76.5 17.2 7.6e-05 23.0 0.6 5.5 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORZ00354.1 - 4.2e-07 29.6 17.3 5.6 7.9 0.2 8.3 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.6 ORZ00354.1 - 0.0025 17.3 9.4 0.64 9.5 0.9 3.1 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 ORZ00354.1 - 0.0045 16.9 21.2 6.7 7.0 0.5 6.2 7 0 0 7 7 7 4 Leucine Rich repeat ORC6 PF05460.13 ORZ00354.1 - 0.031 13.6 5.6 0.047 13.0 5.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM199X PF15814.5 ORZ00354.1 - 0.084 11.9 0.3 0.16 11.0 0.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X ANAPC10 PF03256.16 ORZ00355.1 - 2.7e-41 141.3 0.0 3.5e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SUa-2TM PF18179.1 ORZ00355.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DFP PF04127.15 ORZ00356.1 - 7.9e-19 68.2 0.0 4.1e-10 39.8 0.0 2.3 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein DUF2252 PF10009.9 ORZ00356.1 - 0.055 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) PI3_PI4_kinase PF00454.27 ORZ00357.1 - 1.9e-31 109.8 0.1 3.3e-30 105.7 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 ORZ00357.1 - 2.8e-10 40.0 0.0 6.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 ORZ00357.1 - 0.00028 20.3 0.7 0.00046 19.6 0.1 1.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 ORZ00357.1 - 0.032 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) SUIM_assoc PF16619.5 ORZ00358.1 - 8.7e-05 22.5 0.0 0.00062 19.8 0.0 2.5 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 PolyA_pol PF01743.20 ORZ00358.1 - 0.77 10.2 4.6 0.76 10.2 3.2 1.7 1 1 0 1 1 1 0 Poly A polymerase head domain TMF_DNA_bd PF12329.8 ORZ00358.1 - 1.3 9.1 15.1 1.1 9.3 0.8 3.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 ORZ00358.1 - 5.7 7.3 10.4 0.24 11.7 0.4 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family PGM_PMM_I PF02878.16 ORZ00359.1 - 8.5e-40 135.7 0.0 2.1e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ORZ00359.1 - 6.7e-26 90.9 0.0 1.5e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ORZ00359.1 - 1.9e-15 57.1 0.2 3e-15 56.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 ORZ00359.1 - 3.5e-07 30.3 0.0 1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ribonuclease_T2 PF00445.18 ORZ00360.1 - 9.6e-34 117.2 0.1 1.2e-33 116.9 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SSF PF00474.17 ORZ00361.1 - 5.4e-21 74.9 33.1 8.2e-21 74.3 33.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Herpes_UL1 PF05259.11 ORZ00361.1 - 0.07 13.2 0.6 1.8 8.7 0.1 2.4 1 1 1 2 2 2 0 Herpesvirus glycoprotein L RRP14 PF15459.6 ORZ00361.1 - 0.076 13.6 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 CAF1 PF04857.20 ORZ00362.1 - 9.2e-51 172.9 0.0 3.6e-29 101.9 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 ORZ00362.1 - 0.00035 20.3 0.5 0.14 11.9 0.0 2.9 3 1 0 3 3 3 2 3'-5' exonuclease AAL_decarboxy PF03306.13 ORZ00362.1 - 0.029 13.7 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase Glyco_tranf_2_3 PF13641.6 ORZ00363.1 - 1e-29 104.1 0.1 1.3e-29 103.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORZ00363.1 - 7.5e-11 42.1 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORZ00363.1 - 3.4e-09 36.4 0.6 7e-08 32.1 0.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.6 ORZ00363.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family Chitin_synth_2 PF03142.15 ORZ00363.1 - 0.026 13.2 7.3 0.12 11.0 7.3 1.9 1 1 0 1 1 1 0 Chitin synthase SNase PF00565.17 ORZ00364.1 - 2.3e-17 63.4 0.0 3.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue LSM PF01423.22 ORZ00365.1 - 7.7e-21 73.6 0.2 8.5e-21 73.4 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORZ00365.1 - 0.02 15.0 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 ORZ00365.1 - 0.037 14.1 0.0 0.055 13.6 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain WASH_WAHD PF11945.8 ORZ00366.1 - 0.078 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex zf-C2H2_aberr PF17017.5 ORZ00367.1 - 4.3e-05 23.7 1.4 0.0098 16.0 0.1 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORZ00367.1 - 0.23 12.0 0.5 0.23 12.0 0.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ00367.1 - 2.7 9.1 11.8 5.5 8.1 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger FMO-like PF00743.19 ORZ00368.1 - 3.3e-20 72.0 0.2 5.8e-19 67.9 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORZ00368.1 - 5.7e-08 32.3 1.1 2.7e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORZ00368.1 - 7.8e-08 32.4 0.0 6.2e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORZ00368.1 - 5.1e-06 26.0 0.1 0.00018 20.9 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORZ00368.1 - 2.6e-05 23.6 0.0 0.085 12.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORZ00368.1 - 0.0057 16.3 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORZ00368.1 - 0.0073 16.3 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORZ00368.1 - 0.1 11.8 0.1 4.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 ORZ00368.1 - 0.16 11.0 0.1 15 4.5 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Cyclin_N PF00134.23 ORZ00369.1 - 1.4e-37 128.2 1.4 5.2e-37 126.4 0.6 2.3 2 1 1 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORZ00369.1 - 1.6e-22 79.9 0.1 6.8e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain TED_complement PF07678.14 ORZ00369.1 - 0.0036 16.4 0.0 0.027 13.5 0.0 2.0 1 1 1 2 2 2 1 A-macroglobulin TED domain Got1 PF04178.12 ORZ00370.1 - 6.2e-35 120.0 16.8 9.7e-35 119.4 16.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3094 PF11293.8 ORZ00370.1 - 0.1 12.3 0.4 0.34 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) EcsB PF05975.12 ORZ00370.1 - 0.49 9.2 14.0 0.63 8.8 14.0 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF2207 PF09972.9 ORZ00370.1 - 8.1 5.1 10.9 43 2.7 10.9 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Arginase PF00491.21 ORZ00371.1 - 2.5e-73 247.0 0.2 2.9e-73 246.8 0.2 1.0 1 0 0 1 1 1 1 Arginase family Ank_2 PF12796.7 ORZ00372.1 - 1.4e-22 80.1 0.1 1.6e-08 35.0 0.0 3.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORZ00372.1 - 1.5e-18 66.9 7.0 7.7e-07 29.6 0.0 5.3 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ00372.1 - 8.2e-12 44.2 4.7 0.0059 17.0 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 ORZ00372.1 - 8.8e-12 45.0 7.3 0.00037 20.7 0.1 5.9 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ORZ00372.1 - 1.9e-09 37.5 6.8 0.00073 19.9 0.0 5.7 5 1 0 5 5 5 2 Ankyrin repeat HAGH_C PF16123.5 ORZ00373.1 - 4.7e-24 84.7 0.4 9.1e-24 83.8 0.4 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORZ00373.1 - 1.3e-10 41.6 1.2 6.9e-09 36.0 1.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORZ00373.1 - 0.0081 15.7 0.3 0.021 14.3 0.2 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain EB1 PF03271.17 ORZ00374.1 - 2e-16 60.0 0.1 3.4e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORZ00374.1 - 1.4e-05 25.2 0.1 2.2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Formyl_trans_N PF00551.19 ORZ00375.1 - 3.9e-30 104.9 0.0 6.1e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 ORZ00375.1 - 4.8e-06 26.7 0.0 1.5e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain PX PF00787.24 ORZ00376.1 - 3.3e-09 36.7 0.2 6e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 ORZ00376.1 - 0.00045 20.1 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Dynactin_p62 PF05502.13 ORZ00377.1 - 3.9e-89 299.6 18.7 1.7e-49 168.9 11.5 2.1 1 1 1 2 2 2 2 Dynactin p62 family Yos1 PF08571.10 ORZ00378.1 - 4.8e-36 122.9 1.6 5.4e-36 122.7 1.6 1.0 1 0 0 1 1 1 1 Yos1-like SET PF00856.28 ORZ00379.1 - 4e-08 33.8 0.0 2.7e-07 31.1 0.0 2.3 2 2 0 2 2 2 1 SET domain Crystallin PF00525.18 ORZ00379.1 - 0.15 12.2 0.0 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Alpha crystallin A chain, N terminal Zn_ribbon_17 PF17120.5 ORZ00380.1 - 4.2e-09 35.9 15.5 4.2e-09 35.9 15.5 2.7 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 ORZ00380.1 - 3.7e-08 33.9 20.8 0.034 15.0 0.3 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 ORZ00380.1 - 7.8e-06 26.1 10.3 2.2e-05 24.6 10.3 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family DZR PF12773.7 ORZ00380.1 - 0.0001 22.3 7.4 0.0002 21.3 7.4 1.5 1 0 0 1 1 1 1 Double zinc ribbon ANAPC4_WD40 PF12894.7 ORZ00380.1 - 0.035 14.4 0.2 5.1 7.5 0.0 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain rve PF00665.26 ORZ00380.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zinc_ribbon_2 PF13240.6 ORZ00380.1 - 0.17 11.6 7.9 0.046 13.4 1.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ORZ00380.1 - 0.6 10.9 7.4 6 7.7 7.4 2.3 1 1 0 1 1 1 0 zinc-ribbon family zf-rbx1 PF12678.7 ORZ00380.1 - 2 8.8 11.9 5.9 7.3 11.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ribbon_3 PF13248.6 ORZ00380.1 - 3.4 7.2 6.5 5.5 6.5 1.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Acyltransferase PF01553.21 ORZ00383.1 - 1.2e-19 70.3 0.0 2.6e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase TetR_C_24 PF17932.1 ORZ00383.1 - 0.0015 18.8 0.2 0.0055 17.0 0.1 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain DUF148 PF02520.17 ORZ00383.1 - 0.43 10.7 4.2 0.28 11.3 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 Ribosomal_L37e PF01907.19 ORZ00384.1 - 6.5e-27 93.5 12.3 6.5e-27 93.5 12.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e zf-ribbon_3 PF13248.6 ORZ00384.1 - 0.004 16.5 1.4 0.0067 15.8 1.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 ORZ00384.1 - 0.0048 16.9 1.7 0.0074 16.3 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORZ00384.1 - 0.019 15.0 1.2 0.028 14.4 1.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S14 PF00253.21 ORZ00384.1 - 0.093 12.5 0.4 0.093 12.5 0.4 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-RING_5 PF14634.6 ORZ00384.1 - 0.1 12.6 3.7 0.16 12.0 3.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORZ00384.1 - 0.14 12.1 3.4 0.19 11.6 3.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 ORZ00384.1 - 0.15 11.5 3.0 0.16 11.4 2.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) zf-C3HC4_2 PF13923.6 ORZ00384.1 - 0.23 11.3 5.1 0.38 10.6 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ00384.1 - 0.25 11.3 5.1 0.39 10.6 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyd_oper_YbgE PF09600.10 ORZ00385.1 - 0.037 14.4 0.6 0.68 10.3 0.2 2.0 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Mis12 PF05859.12 ORZ00386.1 - 3.5e-20 72.5 2.0 5.9e-20 71.7 2.0 1.4 1 0 0 1 1 1 1 Mis12 protein DUF1013 PF06242.11 ORZ00386.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) DUF4404 PF14357.6 ORZ00386.1 - 1.1 9.9 7.6 12 6.6 0.1 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) BTB PF00651.31 ORZ00387.1 - 3e-05 24.2 0.1 0.00013 22.2 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Mucin PF01456.17 ORZ00387.1 - 0.013 15.4 29.7 0.025 14.6 29.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein BAT2_N PF07001.11 ORZ00387.1 - 1.1 9.7 7.5 1.9 8.9 7.5 1.3 1 0 0 1 1 1 0 BAT2 N-terminus DUSP PF06337.12 ORZ00388.1 - 4e-06 27.4 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 DUSP domain zf-Sec23_Sec24 PF04810.15 ORZ00388.1 - 0.00057 19.9 0.3 0.0014 18.6 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger F-box PF00646.33 ORZ00388.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain DZR PF12773.7 ORZ00388.1 - 0.24 11.5 4.4 2.7 8.1 1.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF3507 PF12015.8 ORZ00389.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) GET2 PF08690.10 ORZ00389.1 - 3.8 7.1 10.3 0.12 12.1 0.2 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 Aim21 PF11489.8 ORZ00390.1 - 0.0062 15.5 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 21 FMO-like PF00743.19 ORZ00391.1 - 9.5e-15 54.0 1.0 1.1e-13 50.5 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORZ00391.1 - 7.3e-12 45.1 0.0 2.2e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORZ00391.1 - 1.9e-06 27.4 0.0 0.00045 19.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORZ00391.1 - 0.00056 19.2 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORZ00391.1 - 0.11 12.5 0.1 4.6 7.2 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Peptidase_C57 PF03290.13 ORZ00391.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase FMO-like PF00743.19 ORZ00392.1 - 1.6e-14 53.2 1.1 6.5e-13 47.9 0.4 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORZ00392.1 - 1.6e-12 47.5 0.1 5.9e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORZ00392.1 - 3.3e-10 39.6 1.1 2e-07 30.5 0.1 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORZ00392.1 - 1.5e-07 31.3 0.0 8.9e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORZ00392.1 - 1.5e-06 28.3 0.1 0.0067 16.4 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORZ00392.1 - 2e-06 27.3 1.5 0.00022 20.6 0.6 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORZ00392.1 - 7.7e-06 25.3 0.4 0.015 14.6 0.5 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORZ00392.1 - 8.7e-05 21.9 0.8 0.0066 15.7 0.2 2.2 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 ORZ00392.1 - 0.00012 21.5 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 ORZ00392.1 - 0.0035 16.5 0.8 0.084 11.9 0.3 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORZ00392.1 - 0.0077 16.8 0.6 0.093 13.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORZ00392.1 - 0.034 13.5 0.4 0.075 12.4 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_M15_4 PF13539.6 ORZ00392.1 - 0.046 14.2 0.2 0.42 11.2 0.0 2.4 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Trp_halogenase PF04820.14 ORZ00392.1 - 0.12 11.1 1.0 0.55 9.0 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 ORZ00392.1 - 0.13 11.5 0.1 1.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORZ00392.1 - 0.2 10.3 1.1 0.55 8.9 0.6 1.9 2 0 0 2 2 2 0 HI0933-like protein CUE PF02845.16 ORZ00393.1 - 1.4e-06 27.9 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 ORZ00393.1 - 0.0089 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HGTP_anticodon PF03129.20 ORZ00394.1 - 1e-12 48.0 0.0 2.7e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORZ00394.1 - 2.5e-12 47.1 0.0 4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-CDGSH PF09360.10 ORZ00395.1 - 1e-06 28.9 3.9 0.016 15.4 0.2 2.7 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type NFACT-C PF11923.8 ORZ00395.1 - 0.28 11.1 2.2 2.4 8.1 0.4 2.1 2 0 0 2 2 2 0 NFACT protein C-terminal domain DUF2681 PF10883.8 ORZ00395.1 - 5.8 7.4 9.3 1.7 9.1 6.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) CorA PF01544.18 ORZ00396.1 - 7e-39 133.9 0.5 1.2e-38 133.1 0.5 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein GPI-anchored PF10342.9 ORZ00397.1 - 2.7e-14 53.7 0.0 7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_7 PF17957.1 ORZ00397.1 - 0.00073 20.3 0.4 0.002 18.9 0.4 1.7 1 0 0 1 1 1 1 Bacterial Ig domain SOG2 PF10428.9 ORZ00397.1 - 0.17 11.1 10.4 0.17 11.0 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MOZ_SAS PF01853.18 ORZ00399.1 - 2e-71 239.4 0.0 2.9e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORZ00399.1 - 1.3e-18 66.4 0.6 3.1e-18 65.1 0.6 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 ORZ00399.1 - 1.7e-05 25.1 0.0 3.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORZ00399.1 - 4.1e-05 23.8 0.0 7.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORZ00399.1 - 0.0047 16.9 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORZ00399.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ORC6 PF05460.13 ORZ00399.1 - 0.023 14.0 0.1 0.031 13.6 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) p450 PF00067.22 ORZ00400.1 - 3.1e-33 115.2 0.0 3.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_chap PF03280.14 ORZ00400.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein p450 PF00067.22 ORZ00401.1 - 0.00032 19.6 0.0 0.00039 19.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 7tm_2 PF00002.24 ORZ00403.1 - 0.048 13.0 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) zf-RING_2 PF13639.6 ORZ00404.1 - 1.6e-10 41.1 12.2 2.5e-10 40.5 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORZ00404.1 - 9.6e-10 38.0 1.6 2.3e-09 36.8 1.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORZ00404.1 - 9.4e-07 29.0 8.7 1.7e-06 28.2 8.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORZ00404.1 - 9.8e-07 28.5 12.3 1.6e-06 27.9 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ00404.1 - 3.4e-06 26.8 8.2 5.4e-06 26.2 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORZ00404.1 - 0.00013 21.9 3.3 0.00027 20.9 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORZ00404.1 - 0.0014 18.6 10.2 0.002 18.0 10.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORZ00404.1 - 0.0017 18.2 8.6 0.0025 17.7 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORZ00404.1 - 0.009 16.0 2.6 0.009 16.0 2.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger GspL_C PF12693.7 ORZ00404.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 GspL periplasmic domain Prok-RING_4 PF14447.6 ORZ00404.1 - 0.021 14.6 6.8 0.039 13.8 6.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LapA_dom PF06305.11 ORZ00404.1 - 0.058 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-RING_4 PF14570.6 ORZ00404.1 - 0.097 12.5 8.4 0.16 11.8 8.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORZ00404.1 - 0.83 9.8 7.9 1.5 9.0 7.9 1.4 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 ORZ00404.1 - 0.86 9.3 9.0 1.5 8.5 9.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORZ00404.1 - 6.1 7.1 8.7 31 4.8 8.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF202 PF02656.15 ORZ00405.1 - 4.4e-13 49.5 0.5 4.4e-13 49.5 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TPR_2 PF07719.17 ORZ00406.1 - 8.5e-10 38.0 0.2 0.00036 20.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ00406.1 - 8.3e-08 31.7 0.0 0.36 10.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ00406.1 - 3.4e-06 27.5 0.3 6.6e-06 26.5 0.3 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ00406.1 - 9e-06 25.8 0.0 3.9e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ00406.1 - 1.9e-05 24.9 0.9 2.7 8.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00406.1 - 2.2e-05 25.0 0.1 0.00039 21.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ00406.1 - 3e-05 24.5 0.7 0.00039 21.0 0.2 2.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ00406.1 - 0.0006 20.3 2.0 0.0014 19.2 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ00406.1 - 0.0012 18.7 0.0 6.7 7.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ00406.1 - 0.0066 16.6 0.1 0.059 13.6 0.2 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 ORZ00406.1 - 0.0067 16.7 0.8 2.1 8.9 0.0 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORZ00406.1 - 0.012 15.4 0.1 8.9 6.3 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORZ00406.1 - 0.016 15.8 0.2 0.016 15.8 0.2 1.9 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ00406.1 - 0.022 14.9 0.6 0.94 9.9 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ00406.1 - 0.024 14.3 0.0 11 5.8 0.0 2.8 2 1 1 3 3 3 0 TPR repeat PPR PF01535.20 ORZ00406.1 - 0.11 12.7 0.0 4.4 7.8 0.0 2.9 2 0 0 2 2 2 0 PPR repeat Arrestin_N PF00339.29 ORZ00407.1 - 2.8e-06 27.5 0.0 8.2e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORZ00407.1 - 0.0047 17.4 0.0 0.23 11.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rrn6 PF10214.9 ORZ00408.1 - 3.4e-06 25.9 0.7 4.6e-06 25.5 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor zf-NOSIP PF15906.5 ORZ00409.1 - 6.1e-15 55.1 1.2 6.1e-15 55.1 1.2 2.1 3 0 0 3 3 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 ORZ00409.1 - 2.4e-10 40.1 19.0 9.6e-07 28.6 9.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORZ00409.1 - 8.1e-07 29.0 14.9 0.0043 17.0 6.3 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 ORZ00409.1 - 9.9e-07 28.6 19.1 8.6e-06 25.6 10.1 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 ORZ00409.1 - 1.8e-06 28.2 17.2 1.6e-05 25.1 7.8 2.4 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.12 ORZ00409.1 - 3.3e-06 26.6 8.0 3.3e-06 26.6 8.0 2.9 1 1 1 3 3 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 ORZ00409.1 - 1.8e-05 24.5 20.1 0.0031 17.3 9.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORZ00409.1 - 3.3e-05 23.6 19.8 0.0018 18.1 9.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORZ00409.1 - 0.0001 22.1 19.7 0.025 14.4 9.1 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORZ00409.1 - 0.0018 18.4 18.0 0.14 12.3 2.2 3.0 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING UPF0547 PF10571.9 ORZ00409.1 - 0.072 13.2 2.0 0.17 12.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FYVE PF01363.21 ORZ00409.1 - 0.31 11.2 16.5 0.039 14.1 7.7 2.8 2 1 0 2 2 2 0 FYVE zinc finger zf-P11 PF03854.14 ORZ00409.1 - 1.1 9.0 16.6 1.6 8.4 7.9 2.7 2 1 0 2 2 2 0 P-11 zinc finger TAF4 PF05236.14 ORZ00409.1 - 1.2 8.8 11.8 4.7 6.9 11.8 2.0 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-RING_10 PF16685.5 ORZ00409.1 - 1.3 9.2 16.2 2.6 8.3 7.7 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 Ndc1_Nup PF09531.10 ORZ00409.1 - 9.2 4.8 7.4 11 4.6 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HSF_DNA-bind PF00447.17 ORZ00410.1 - 1.4e-30 105.7 0.1 4.3e-30 104.2 0.1 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 ORZ00410.1 - 6.5e-27 93.9 0.4 1.5e-26 92.7 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 ORZ00410.1 - 0.19 12.2 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Ets-domain HMGL-like PF00682.19 ORZ00411.1 - 8e-60 202.6 0.0 9.4e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 HMGL-like SUIM_assoc PF16619.5 ORZ00411.1 - 0.025 14.6 3.0 0.067 13.3 3.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cyt-b5 PF00173.28 ORZ00412.1 - 1.2e-23 83.0 0.2 2.3e-23 82.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ORZ00412.1 - 1.3e-12 48.2 15.1 1.3e-12 48.2 15.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMEM189_B_dmain PF10520.9 ORZ00412.1 - 1.2 9.2 9.7 0.098 12.8 1.5 2.5 3 0 0 3 3 3 0 B domain of TMEM189, localisation domain AbrB_C PF18277.1 ORZ00414.1 - 0.006 16.2 0.2 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 AbrB C-terminal domain TPR_19 PF14559.6 ORZ00414.1 - 0.081 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SGTA_dimer PF16546.5 ORZ00415.1 - 9.9e-26 89.3 0.1 2.2e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 ORZ00415.1 - 3.3e-12 45.7 6.8 0.00035 20.2 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ00415.1 - 3.3e-11 42.7 8.2 2.8e-05 23.7 2.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 ORZ00415.1 - 1.7e-09 37.0 9.7 0.0018 18.2 0.2 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ00415.1 - 1.9e-07 30.7 1.7 0.065 13.5 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ00415.1 - 2.5e-07 30.2 3.4 0.052 13.6 2.0 3.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ00415.1 - 8e-07 29.0 1.5 0.00038 20.6 0.9 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00415.1 - 7e-06 26.6 3.7 0.0015 19.1 1.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ00415.1 - 3.1e-05 24.4 3.9 0.022 15.5 1.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ00415.1 - 8.9e-05 22.9 7.2 0.023 15.2 1.4 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ00415.1 - 0.00014 22.0 5.7 0.0019 18.4 5.4 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORZ00415.1 - 0.0053 16.6 4.3 0.51 10.3 2.4 3.6 4 1 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.18 ORZ00415.1 - 0.012 15.7 10.7 0.16 12.1 0.2 3.0 2 2 0 2 2 2 0 MIT (microtubule interacting and transport) domain TetR_C_28 PF17937.1 ORZ00415.1 - 0.28 11.7 1.4 9.2 6.8 0.2 2.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain STI1 PF17830.1 ORZ00415.1 - 0.87 9.6 16.6 13 5.8 1.1 2.5 1 1 2 3 3 3 0 STI1 domain HLH PF00010.26 ORZ00417.1 - 2.7e-09 36.8 0.2 2.7e-09 36.8 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PhyH PF05721.13 ORZ00418.1 - 9.2e-12 45.7 0.1 1.5e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CN_hydrolase PF00795.22 ORZ00419.1 - 2.9e-18 66.2 0.0 4.1e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Sec1 PF00995.23 ORZ00420.1 - 3e-135 452.7 8.4 3.4e-135 452.5 8.4 1.0 1 0 0 1 1 1 1 Sec1 family Qua1 PF16274.5 ORZ00420.1 - 0.084 12.7 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 Qua1 domain UPF0449 PF15136.6 ORZ00420.1 - 0.32 11.5 2.8 0.4 11.2 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Homeodomain PF00046.29 ORZ00423.1 - 4.7e-20 71.2 4.9 5.1e-20 71.1 4.9 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORZ00423.1 - 0.00026 20.8 0.4 0.00046 20.0 0.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain NUDIX PF00293.28 ORZ00424.1 - 8.1e-15 55.0 0.5 9.6e-15 54.8 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain betaPIX_CC PF16523.5 ORZ00425.1 - 0.16 11.8 5.4 0.65 9.9 4.5 2.2 2 0 0 2 2 2 0 betaPIX coiled coil YwqJ-deaminase PF14431.6 ORZ00425.1 - 7.7 6.7 10.4 0.56 10.4 0.3 3.1 3 0 0 3 3 3 0 YwqJ-like deaminase Dcc1 PF09724.9 ORZ00426.1 - 0.092 12.0 2.1 0.1 11.9 2.1 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Kelch_4 PF13418.6 ORZ00428.1 - 1.2e-21 76.5 9.2 3.3e-05 23.8 0.4 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 ORZ00428.1 - 4.4e-20 71.2 12.9 8.4e-06 25.9 0.2 6.7 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 ORZ00428.1 - 1.7e-17 63.2 18.3 7.7e-07 29.3 0.5 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 ORZ00428.1 - 1.2e-16 59.9 10.4 5.3e-05 23.0 0.0 7.0 8 1 0 8 8 8 3 Kelch motif Kelch_5 PF13854.6 ORZ00428.1 - 4.6e-16 58.4 4.9 0.0015 18.5 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORZ00428.1 - 1e-10 41.0 0.1 0.0062 16.1 0.0 4.6 4 0 0 4 4 4 2 Kelch motif YqhR PF11085.8 ORZ00428.1 - 0.00056 19.9 1.2 0.00091 19.2 0.0 1.9 2 0 0 2 2 2 1 Conserved membrane protein YqhR VSP PF03302.13 ORZ00428.1 - 0.0098 14.8 0.4 0.0098 14.8 0.4 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein RCC1_2 PF13540.6 ORZ00428.1 - 0.022 14.5 0.2 9.9 6.1 0.0 3.1 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat ASC PF00858.24 ORZ00428.1 - 0.11 11.4 0.0 0.11 11.4 0.0 3.1 1 1 0 3 3 3 0 Amiloride-sensitive sodium channel Amnionless PF14828.6 ORZ00428.1 - 0.15 10.9 0.1 0.31 9.8 0.0 1.5 1 1 0 1 1 1 0 Amnionless Pkr1 PF08636.10 ORZ00428.1 - 1.2 9.3 8.0 9.2 6.5 0.5 3.5 3 0 0 3 3 3 0 ER protein Pkr1 DUF4131 PF13567.6 ORZ00428.1 - 5.8 6.5 7.4 0.4 10.3 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CTP_transf_like PF01467.26 ORZ00429.1 - 8.8e-08 32.4 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like ELO PF01151.18 ORZ00430.1 - 1e-56 192.3 26.6 1.2e-56 192.0 26.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Orn_Arg_deC_N PF02784.16 ORZ00431.1 - 4e-79 265.5 0.0 5e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORZ00431.1 - 2.1e-19 69.5 0.0 2.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 ORZ00431.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel polyprenyl_synt PF00348.17 ORZ00432.1 - 2.5e-40 138.2 0.9 1.7e-39 135.4 0.9 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 ORZ00432.1 - 0.0062 16.2 0.1 0.0093 15.6 0.1 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 SQS_PSY PF00494.19 ORZ00432.1 - 0.013 15.0 1.3 0.048 13.2 1.3 1.9 1 1 0 1 1 1 0 Squalene/phytoene synthase PCI PF01399.27 ORZ00433.1 - 7.3e-11 42.5 1.2 3.5e-10 40.3 0.1 2.7 2 1 0 2 2 2 1 PCI domain Rad60-SLD PF11976.8 ORZ00434.1 - 1.3e-23 82.6 0.0 1.5e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORZ00434.1 - 1.5e-11 43.9 0.0 1.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DEAD PF00270.29 ORZ00435.1 - 6.1e-45 153.1 0.0 1e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ00435.1 - 6.1e-31 107.0 0.0 9.3e-28 96.8 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain GUCT PF08152.12 ORZ00435.1 - 3.5e-18 65.7 0.0 1.1e-17 64.1 0.0 1.9 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.15 ORZ00435.1 - 1.8e-06 28.1 0.0 4.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORZ00435.1 - 0.0027 17.1 2.8 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Cyclin_N PF00134.23 ORZ00436.1 - 9.5e-09 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORZ00436.1 - 3.8e-05 24.1 0.3 0.00023 21.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin Tgi2PP PF18250.1 ORZ00436.1 - 0.03 14.5 0.0 0.097 12.9 0.0 1.8 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP CENP-M PF11111.8 ORZ00437.1 - 1.5e-11 43.8 0.0 1.9e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) TrkA_N PF02254.18 ORZ00437.1 - 0.0089 16.3 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain GTP_EFTU PF00009.27 ORZ00437.1 - 0.037 13.6 0.1 4.1 6.9 0.1 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 ORZ00437.1 - 0.11 12.7 0.0 0.41 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ORZ00437.1 - 0.12 12.2 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SNF2_N PF00176.23 ORZ00438.1 - 6.7e-73 245.4 0.1 6.7e-73 245.4 0.1 2.6 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORZ00438.1 - 1.1e-19 70.8 0.8 1.4e-18 67.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 ORZ00438.1 - 4.4e-18 65.4 6.0 4.4e-18 65.4 6.0 3.5 4 0 0 4 4 4 1 HSA SnAC PF14619.6 ORZ00438.1 - 4.8e-15 55.9 3.0 4.8e-15 55.9 3.0 3.7 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 ORZ00438.1 - 1.3e-11 44.8 3.7 1.9e-11 44.2 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORZ00438.1 - 1.4e-05 24.4 0.2 0.00021 20.6 0.1 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 ORZ00438.1 - 3.5e-05 23.6 1.7 8.5e-05 22.3 0.0 2.6 2 1 0 2 2 2 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 ORZ00438.1 - 0.093 12.8 0.4 0.79 9.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Drf_GBD PF06371.13 ORZ00440.1 - 3e-20 72.6 0.0 9.6e-20 70.9 0.0 1.8 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain HJURP_C PF12347.8 ORZ00440.1 - 0.1 12.7 0.3 0.1 12.7 0.3 2.3 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat adh_short_C2 PF13561.6 ORZ00441.1 - 3.5e-69 232.9 0.4 4e-69 232.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORZ00441.1 - 9.2e-54 181.9 0.6 1.2e-53 181.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORZ00441.1 - 2.2e-16 60.3 0.9 3.1e-16 59.8 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORZ00441.1 - 9.6e-05 22.0 0.2 0.00013 21.5 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SUIM_assoc PF16619.5 ORZ00444.1 - 0.013 15.5 19.7 0.013 15.5 19.7 7.6 4 3 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DHHC PF01529.20 ORZ00445.1 - 1.2e-38 132.3 5.0 1.7e-38 131.8 5.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase LapA_dom PF06305.11 ORZ00445.1 - 0.039 13.8 0.5 0.092 12.6 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RGS PF00615.19 ORZ00446.1 - 2.6e-15 56.7 4.1 2.6e-15 56.7 4.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain SUIM_assoc PF16619.5 ORZ00446.1 - 0.0077 16.3 3.2 0.019 15.0 3.2 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Prok-E2_E PF14462.6 ORZ00446.1 - 0.015 15.1 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family E TMEM70 PF06979.12 ORZ00447.1 - 0.016 15.6 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex Bacteriocin_IIi PF11758.8 ORZ00447.1 - 0.026 14.4 0.2 0.057 13.2 0.1 1.6 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin DUF1418 PF07214.12 ORZ00447.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Kelch_1 PF01344.25 ORZ00448.1 - 1.6e-43 146.0 14.3 3.3e-10 39.4 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 ORZ00448.1 - 1.3e-41 140.0 17.2 1.7e-09 37.4 0.5 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ORZ00448.1 - 1.3e-40 137.0 17.1 7.3e-08 32.5 0.1 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 ORZ00448.1 - 2.3e-40 136.4 16.5 1.7e-08 34.3 0.1 6.1 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 ORZ00448.1 - 6.9e-31 105.5 19.7 2e-08 34.2 0.2 6.1 2 2 4 6 6 6 5 Kelch motif Kelch_2 PF07646.15 ORZ00448.1 - 1.7e-29 100.7 15.3 4.7e-06 26.4 0.2 6.1 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.6 ORZ00448.1 - 0.00079 19.8 6.7 3.9 8.1 0.3 5.8 6 0 0 6 6 6 1 PQQ-like domain DHHC PF01529.20 ORZ00449.1 - 4.5e-38 130.4 7.4 4.5e-38 130.4 7.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pox_A14 PF05767.12 ORZ00449.1 - 0.1 12.8 5.7 0.43 10.8 0.2 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 MAT1 PF06391.13 ORZ00450.1 - 6.4 6.5 11.4 0.98 9.2 4.8 2.5 2 1 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 RhoGEF PF00621.20 ORZ00451.1 - 1e-20 74.8 0.1 1.1e-20 74.7 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain Chitin_synth_2 PF03142.15 ORZ00452.1 - 2e-278 924.3 0.3 2.7e-278 923.9 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORZ00452.1 - 4.7e-13 49.6 0.0 2.6e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORZ00452.1 - 2.4e-12 47.2 1.3 7.7e-12 45.5 1.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORZ00452.1 - 0.0019 17.7 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORZ00452.1 - 0.19 11.5 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 TPP_enzyme_N PF02776.18 ORZ00453.1 - 3.3e-52 176.6 0.7 2.1e-50 170.7 0.1 2.9 2 1 2 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORZ00453.1 - 2.1e-38 131.1 0.0 5e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORZ00453.1 - 1.4e-24 86.7 0.0 4.2e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORZ00453.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2007 PF09413.10 ORZ00453.1 - 0.067 13.4 0.1 8.2 6.7 0.0 3.2 3 0 0 3 3 3 0 Putative prokaryotic signal transducing protein B12-binding PF02310.19 ORZ00453.1 - 0.1 12.6 0.4 0.26 11.3 0.4 1.6 1 0 0 1 1 1 0 B12 binding domain adh_short PF00106.25 ORZ00454.1 - 4.8e-43 146.9 2.8 6.7e-43 146.4 2.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ00454.1 - 2.4e-38 132.0 1.0 3.3e-38 131.6 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORZ00454.1 - 0.026 14.4 1.9 0.057 13.3 1.9 1.5 1 1 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.19 ORZ00454.1 - 0.047 13.0 0.2 0.083 12.2 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phage_Treg PF04761.12 ORZ00454.1 - 0.23 11.6 0.6 1.2 9.3 0.1 2.3 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator adh_short PF00106.25 ORZ00455.1 - 1.4e-40 138.9 0.7 1.8e-40 138.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ00455.1 - 2.1e-35 122.4 0.1 2.8e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORZ00455.1 - 0.00053 19.9 0.3 0.00086 19.3 0.3 1.3 1 0 0 1 1 1 1 KR domain T2SSE PF00437.20 ORZ00455.1 - 0.022 13.8 0.1 0.073 12.1 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein WD40 PF00400.32 ORZ00456.1 - 2.1e-41 139.1 16.5 6.8e-06 26.7 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 ORZ00456.1 - 2.2e-10 40.3 0.4 5.3e-10 39.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORZ00456.1 - 1.1e-08 35.2 0.3 0.22 11.8 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORZ00456.1 - 4.7e-07 29.5 0.0 1.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ORZ00456.1 - 8.7e-07 28.0 4.2 0.17 10.5 0.0 5.3 4 1 2 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 ORZ00456.1 - 0.00031 20.2 0.0 0.11 11.9 0.0 2.1 1 1 1 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 ORZ00456.1 - 0.00039 20.1 0.3 0.0039 16.8 0.4 2.3 1 1 1 2 2 2 1 PQQ-like domain F-box_4 PF15966.5 ORZ00456.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box TP6A_N PF04406.14 ORZ00457.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Type IIB DNA topoisomerase zf-CCHC PF00098.23 ORZ00458.1 - 0.00077 19.4 3.9 0.00077 19.4 3.9 5.3 5 0 0 5 5 5 3 Zinc knuckle EPL1 PF10513.9 ORZ00458.1 - 1.6 9.1 8.5 0.31 11.4 3.8 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF5601 PF18151.1 ORZ00459.1 - 5.9e-08 32.9 1.0 1e-07 32.1 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) Ku_PK_bind PF08785.11 ORZ00459.1 - 0.021 14.9 0.3 0.044 13.9 0.3 1.5 1 0 0 1 1 1 0 Ku C terminal domain like VPS9 PF02204.18 ORZ00459.1 - 0.12 12.6 0.3 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain DUF3446 PF11928.8 ORZ00460.1 - 0.52 10.6 7.4 0.41 11.0 1.1 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain HLH PF00010.26 ORZ00461.1 - 1.1e-15 57.3 0.3 2e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 ORZ00461.1 - 2.1 8.9 12.7 1 9.9 0.9 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Peptidase_S64 PF08192.11 ORZ00461.1 - 5 5.5 9.1 7.4 4.9 9.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 XG_FTase PF03254.13 ORZ00462.1 - 2.3e-05 23.2 0.0 0.00015 20.5 0.0 2.1 1 1 1 2 2 2 1 Xyloglucan fucosyltransferase CSD PF00313.22 ORZ00463.1 - 3.3e-21 74.9 0.1 4.9e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ORZ00463.1 - 0.014 15.1 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain TFIIA PF03153.13 ORZ00464.1 - 0.047 13.7 8.9 0.051 13.6 8.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORZ00464.1 - 0.15 11.6 8.2 0.15 11.6 8.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF2099 PF09872.9 ORZ00465.1 - 0.0019 17.5 0.2 0.0023 17.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2099) BLOC1_2 PF10046.9 ORZ00465.1 - 0.0075 16.6 2.9 0.013 15.8 2.6 1.5 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 ORZ00465.1 - 0.0093 16.4 3.8 0.0093 16.4 3.8 2.1 1 1 1 2 2 2 1 Spectrin repeat FapA PF03961.13 ORZ00465.1 - 0.015 13.9 0.4 0.018 13.7 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A V-ATPase_C PF03223.15 ORZ00465.1 - 0.025 14.0 1.3 0.084 12.3 1.3 1.7 1 1 0 1 1 1 0 V-ATPase subunit C TMF_TATA_bd PF12325.8 ORZ00465.1 - 0.034 14.4 2.8 0.049 13.8 2.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Ferritin-like PF12902.7 ORZ00465.1 - 0.046 13.6 0.2 0.052 13.4 0.2 1.1 1 0 0 1 1 1 0 Ferritin-like Med29 PF11568.8 ORZ00465.1 - 0.068 13.4 1.4 0.11 12.7 1.3 1.4 1 1 0 1 1 1 0 Mediator complex subunit 29 RasGAP_C PF03836.15 ORZ00465.1 - 0.085 13.0 0.5 0.15 12.2 0.5 1.6 1 1 0 1 1 1 0 RasGAP C-terminus BORCS7 PF16088.5 ORZ00465.1 - 0.089 13.1 2.3 0.13 12.5 1.2 1.7 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF1664 PF07889.12 ORZ00465.1 - 0.11 12.5 2.6 0.14 12.2 2.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ArsR PF09824.9 ORZ00465.1 - 0.14 11.7 1.9 0.19 11.3 1.9 1.1 1 0 0 1 1 1 0 ArsR transcriptional regulator FlaC_arch PF05377.11 ORZ00465.1 - 0.16 12.4 0.8 0.38 11.2 0.3 1.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ERM PF00769.19 ORZ00465.1 - 0.17 11.7 6.6 0.19 11.5 6.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4391 PF14335.6 ORZ00465.1 - 0.18 11.5 4.1 0.21 11.3 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF948 PF06103.11 ORZ00465.1 - 0.23 11.7 2.6 2.9 8.2 1.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4047 PF13256.6 ORZ00465.1 - 0.26 11.5 4.5 0.36 11.0 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Nsp1_C PF05064.13 ORZ00465.1 - 1.4 8.7 9.2 3.4 7.5 9.1 1.6 1 1 0 1 1 1 0 Nsp1-like C-terminal region ParA PF10609.9 ORZ00466.1 - 8.9e-100 333.2 0.0 1e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORZ00466.1 - 5e-10 39.5 0.0 4.6e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 ORZ00466.1 - 2.7e-07 30.2 0.0 5.2e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 ORZ00466.1 - 2.9e-07 30.6 0.9 3.3e-06 27.1 0.9 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 ORZ00466.1 - 0.00013 21.3 1.0 0.00029 20.1 0.3 1.8 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 ORZ00466.1 - 0.0002 20.9 0.1 0.00069 19.2 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 ORZ00466.1 - 0.00028 20.0 0.5 0.00043 19.4 0.5 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 ORZ00466.1 - 0.00029 20.7 0.6 0.6 9.9 0.7 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORZ00466.1 - 0.0079 15.8 0.3 0.015 14.9 0.3 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 ORZ00466.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 ORZ00466.1 - 0.089 12.2 0.1 0.21 11.0 0.1 1.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 ORZ00466.1 - 0.12 12.2 0.2 0.24 11.2 0.1 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 ORZ00466.1 - 0.18 11.7 0.9 0.33 10.8 0.9 1.4 1 0 0 1 1 1 0 RsgA GTPase Zn_Tnp_IS1595 PF12760.7 ORZ00466.1 - 0.23 11.4 1.1 2.1 8.4 0.5 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain SRP54 PF00448.22 ORZ00466.1 - 0.26 10.9 0.5 1.6 8.3 0.4 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Cpn60_TCP1 PF00118.24 ORZ00467.1 - 3.9e-84 283.0 11.1 8.1e-84 282.0 11.1 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family SnoaL_4 PF13577.6 ORZ00467.1 - 0.083 13.0 1.2 1.3 9.2 0.3 2.8 1 1 1 2 2 2 0 SnoaL-like domain AAA_lid_2 PF17863.1 ORZ00467.1 - 0.085 12.7 0.2 2.5 8.0 0.2 2.6 2 0 0 2 2 2 0 AAA lid domain zf-C2H2_aberr PF17017.5 ORZ00468.1 - 0.0071 16.5 15.8 0.05 13.7 1.2 2.7 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORZ00468.1 - 0.018 15.5 0.7 0.018 15.5 0.7 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type SPT6_acidic PF14632.6 ORZ00468.1 - 0.069 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 zf-C2H2_4 PF13894.6 ORZ00468.1 - 5.5 8.1 26.8 1 10.3 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Rad51 PF08423.11 ORZ00469.1 - 0.01 15.1 0.0 0.011 15.0 0.0 1.0 1 0 0 1 1 1 0 Rad51 Methyltransf_8 PF05148.15 ORZ00471.1 - 2.2e-78 263.1 0.0 2.7e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ORZ00471.1 - 1.9e-06 28.4 0.0 1e-05 26.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ00471.1 - 0.00018 22.1 0.0 0.02 15.6 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ00471.1 - 0.0011 18.5 0.0 0.098 12.2 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.16 ORZ00471.1 - 0.0013 17.4 0.0 0.7 8.4 0.0 2.3 2 1 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 ORZ00471.1 - 0.031 14.1 0.1 7.5 6.3 0.1 2.6 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ00471.1 - 0.032 13.6 0.1 3.9 6.8 0.0 2.9 1 1 2 3 3 3 0 ubiE/COQ5 methyltransferase family Bmt2 PF11968.8 ORZ00471.1 - 0.063 13.1 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 ACBP PF00887.19 ORZ00472.1 - 1.3e-25 89.4 0.9 2.5e-25 88.5 0.2 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Ank_4 PF13637.6 ORZ00472.1 - 2.7e-22 78.9 1.8 5.6e-13 49.1 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORZ00472.1 - 2.4e-16 59.6 1.0 1.4e-11 44.4 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORZ00472.1 - 3.6e-15 56.3 0.2 4.7e-09 36.7 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORZ00472.1 - 7.9e-13 47.4 0.1 3.7e-07 29.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORZ00472.1 - 2.9e-12 46.4 3.3 3e-09 36.9 0.7 2.9 4 0 0 4 4 4 2 Ankyrin repeat DUF5023 PF16426.5 ORZ00472.1 - 0.0019 17.9 0.3 0.0027 17.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5023) Bindin PF02084.15 ORZ00472.1 - 0.044 14.1 0.6 0.062 13.6 0.6 1.2 1 0 0 1 1 1 0 Bindin Phosphoesterase PF04185.14 ORZ00473.1 - 8.8e-33 114.0 1.0 4.4e-32 111.7 1.0 1.8 1 1 0 1 1 1 1 Phosphoesterase family F1F0-ATPsyn_F PF10791.9 ORZ00474.1 - 8.4e-35 119.1 0.1 9.5e-35 119.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 ORZ00474.1 - 2.3e-05 24.7 0.0 3e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f DAHP_synth_1 PF00793.20 ORZ00475.1 - 1.9e-100 335.3 0.0 2.4e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF155 PF02582.14 ORZ00476.1 - 2.5e-48 164.5 0.0 3.4e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3302 PF11742.8 ORZ00477.1 - 0.02 15.0 0.7 0.02 15.0 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3302) Ndc1_Nup PF09531.10 ORZ00477.1 - 0.14 10.9 1.9 0.15 10.8 1.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LRR_8 PF13855.6 ORZ00478.1 - 8.6e-34 115.1 59.4 4e-10 39.3 8.6 4.4 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORZ00478.1 - 2.9e-22 78.4 39.7 8.3e-06 26.1 0.6 6.4 3 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORZ00478.1 - 1.7e-11 43.0 31.8 0.085 13.5 2.0 9.9 9 1 0 9 9 9 6 Leucine Rich Repeat FAP PF07174.11 ORZ00478.1 - 0.00021 20.9 7.5 0.00034 20.2 7.5 1.3 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) LRRNT_2 PF08263.12 ORZ00478.1 - 0.0071 16.6 4.9 0.0071 16.6 4.9 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 ORZ00478.1 - 0.076 12.5 9.1 0.4 10.2 0.2 3.1 1 1 2 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 ORZ00478.1 - 0.57 10.4 36.2 0.38 10.9 0.7 8.5 9 0 0 9 9 9 0 Leucine Rich repeat C2 PF00168.30 ORZ00479.1 - 1.1e-23 83.5 0.0 2.4e-23 82.4 0.0 1.5 2 0 0 2 2 2 1 C2 domain Abhydrolase_1 PF00561.20 ORZ00480.1 - 5.2e-27 95.1 0.2 1.5e-21 77.2 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORZ00480.1 - 1.2e-21 77.1 0.0 2e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORZ00480.1 - 3.9e-20 73.4 0.8 7.5e-20 72.5 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ORZ00480.1 - 1.2e-06 28.3 0.0 3.9e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.13 ORZ00480.1 - 8.7e-06 25.7 0.6 0.0038 17.1 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ORZ00480.1 - 1.1e-05 25.3 0.0 0.32 10.8 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ORZ00480.1 - 9.8e-05 22.0 0.0 0.00028 20.5 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ndr PF03096.14 ORZ00480.1 - 0.00031 19.5 0.0 0.0012 17.7 0.0 1.8 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.11 ORZ00480.1 - 0.0072 16.3 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 ORZ00480.1 - 0.0077 15.6 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 ORZ00480.1 - 0.021 14.5 0.2 0.37 10.4 0.0 2.6 4 0 0 4 4 3 0 Serine hydrolase (FSH1) Lipase_3 PF01764.25 ORZ00480.1 - 0.023 14.5 0.0 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) UPF0227 PF05728.12 ORZ00480.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 ORZ00480.1 - 0.028 14.2 0.0 0.58 9.9 0.0 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 ORZ00480.1 - 0.034 13.1 0.0 0.072 12.0 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ORZ00480.1 - 0.048 13.1 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.9 ORZ00480.1 - 0.065 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Thioesterase PF00975.20 ORZ00480.1 - 0.13 12.3 0.8 1 9.5 0.2 2.6 2 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 ORZ00480.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PC-Esterase PF13839.6 ORZ00481.1 - 7.2e-25 88.3 0.8 1.5e-24 87.2 0.4 1.8 2 1 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Glyoxal_oxid_N PF07250.11 ORZ00482.1 - 1.9e-51 174.6 0.0 1.2e-50 171.9 0.0 2.1 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORZ00482.1 - 4.3e-22 78.2 0.0 7.1e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 ORZ00482.1 - 0.0027 17.7 0.5 3.3 7.8 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORZ00482.1 - 0.0048 17.1 1.9 4.7 7.6 0.0 4.6 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.15 ORZ00482.1 - 0.0098 15.8 0.0 1.9 8.6 0.0 3.5 3 0 0 3 3 3 1 Kelch motif RCC1_2 PF13540.6 ORZ00482.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat SKG6 PF08693.10 ORZ00484.1 - 0.038 13.4 0.3 0.27 10.7 0.3 2.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4244 PF14029.6 ORZ00484.1 - 6.2 6.3 5.6 1.8 8.0 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) WD40 PF00400.32 ORZ00486.1 - 4.9e-17 62.0 12.8 0.00039 21.2 0.0 7.9 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00486.1 - 2.4e-14 53.4 1.0 0.0013 19.0 0.0 5.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORZ00486.1 - 0.053 12.5 0.0 0.72 8.7 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5480 PF17576.2 ORZ00487.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Pyr_redox_2 PF07992.14 ORZ00489.1 - 2.3e-44 151.8 1.2 2.9e-44 151.5 1.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 ORZ00489.1 - 5.7e-44 149.6 1.4 4.6e-29 101.4 0.1 2.4 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 ORZ00489.1 - 1.5e-10 41.5 0.3 1.5e-10 41.5 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORZ00489.1 - 4.1e-07 29.6 1.4 1.7e-05 24.3 1.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORZ00489.1 - 7.9e-07 29.2 3.3 0.36 10.8 0.4 4.2 3 1 1 4 4 4 3 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORZ00489.1 - 6.2e-06 25.6 0.1 7.8e-05 22.0 0.0 2.3 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORZ00489.1 - 7.9e-06 25.7 5.0 0.015 14.9 0.6 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORZ00489.1 - 1.4e-05 24.0 0.5 0.014 14.1 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 ORZ00489.1 - 0.0007 19.0 1.8 0.027 13.8 0.3 2.3 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ORZ00489.1 - 0.00092 18.4 0.3 0.034 13.2 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Reductase_C PF14759.6 ORZ00489.1 - 0.0082 16.7 0.0 0.043 14.4 0.0 2.3 2 0 0 2 2 1 1 Reductase C-terminal NAD_binding_8 PF13450.6 ORZ00489.1 - 0.03 14.6 0.8 8.8 6.6 0.1 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORZ00489.1 - 0.033 13.0 0.3 0.61 8.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 ORZ00489.1 - 0.048 14.1 0.2 0.89 10.0 0.5 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding TPP_enzyme_M PF00205.22 ORZ00489.1 - 0.059 13.1 0.2 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain GFO_IDH_MocA PF01408.22 ORZ00489.1 - 0.11 13.3 0.2 1.3 9.9 0.1 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold GIDA PF01134.22 ORZ00489.1 - 0.2 10.7 1.7 13 4.8 0.1 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A TMEM208_SND2 PF05620.11 ORZ00490.1 - 1.5e-58 197.3 1.1 1.7e-58 197.1 1.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 GlyL_C PF12524.8 ORZ00490.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Mito_carr PF00153.27 ORZ00491.1 - 2.4e-55 184.4 2.1 2.1e-17 62.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Phosphoesterase PF04185.14 ORZ00492.1 - 5.5e-30 104.8 3.0 3.7e-29 102.0 3.0 2.0 1 1 0 1 1 1 1 Phosphoesterase family MF_alpha_N PF05436.11 ORZ00492.1 - 0.05 13.5 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus MIF4G_like_2 PF09090.11 ORZ00493.1 - 6.9e-72 242.1 10.2 1.1e-71 241.5 10.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 ORZ00493.1 - 6.9e-51 172.7 0.1 1.3e-50 171.8 0.1 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 ORZ00493.1 - 3.3e-12 46.5 0.1 2.8e-10 40.2 0.0 3.0 3 0 0 3 3 3 1 MIF4G domain PMBR PF09373.10 ORZ00493.1 - 0.019 15.1 0.2 0.54 10.5 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat DUF2408 PF10303.9 ORZ00493.1 - 0.021 15.4 0.5 0.49 11.0 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) PAH PF02671.21 ORZ00493.1 - 0.04 14.1 0.2 1.1 9.5 0.0 3.0 2 0 0 2 2 2 0 Paired amphipathic helix repeat TetR_C_30 PF17939.1 ORZ00493.1 - 0.058 13.6 0.3 0.18 12.1 0.3 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CMS1 PF14617.6 ORZ00494.1 - 3.6e-42 144.4 5.2 4.3e-42 144.2 5.2 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 ORZ00494.1 - 3.6e-06 26.9 0.2 7.5e-06 25.8 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SspO PF08175.12 ORZ00494.1 - 0.71 10.4 7.7 15 6.2 6.5 2.6 2 0 0 2 2 2 0 Small acid-soluble spore protein O family CWC25 PF12542.8 ORZ00494.1 - 1.5 9.8 8.1 1.1 10.2 5.6 2.0 1 1 1 2 2 2 0 Pre-mRNA splicing factor SNF2_N PF00176.23 ORZ00495.1 - 5.9e-67 225.9 4.7 9.9e-66 221.8 4.7 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORZ00495.1 - 6.8e-23 81.1 0.1 2.2e-20 73.0 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORZ00495.1 - 4.8e-09 35.8 0.0 4.8e-09 35.8 0.0 2.9 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PCI PF01399.27 ORZ00496.1 - 1.9e-19 70.1 1.8 3.7e-19 69.2 0.1 2.4 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 ORZ00496.1 - 6.5e-19 67.7 5.2 1.8e-18 66.3 5.2 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF4441 PF14536.6 ORZ00496.1 - 0.18 12.0 9.9 0.7 10.1 9.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) CHDCT2 PF08074.11 ORZ00496.1 - 6 7.0 13.1 1.7 8.8 1.8 3.3 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain TPR_1 PF00515.28 ORZ00497.1 - 2.8e-43 144.0 30.8 4.8e-05 23.0 0.0 10.4 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ00497.1 - 4.5e-42 138.8 25.0 3e-05 23.8 0.0 10.8 10 1 1 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ00497.1 - 9e-36 121.3 12.0 4e-07 29.6 0.3 8.0 5 4 2 7 7 7 6 TPR repeat TPR_16 PF13432.6 ORZ00497.1 - 4e-28 97.8 17.7 1.7e-06 28.6 0.1 7.0 7 1 1 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ00497.1 - 2.3e-26 89.7 28.8 0.00021 21.2 0.0 10.7 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ00497.1 - 6.6e-23 79.4 7.6 0.00072 20.2 0.0 9.8 2 2 8 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ00497.1 - 1.3e-22 78.5 23.0 0.00088 19.5 0.1 9.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ00497.1 - 9.5e-20 70.9 17.6 0.00017 22.0 0.1 7.1 4 2 2 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ00497.1 - 7.1e-16 58.3 22.1 6.9e-05 23.1 0.6 7.4 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ00497.1 - 1.5e-13 50.7 0.1 2.8e-05 24.2 0.0 6.9 2 2 6 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ00497.1 - 5.8e-11 42.5 13.1 0.0012 19.0 0.8 5.5 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORZ00497.1 - 2.9e-09 36.3 11.4 3.3 8.0 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORZ00497.1 - 1.1e-08 34.6 17.2 0.58 10.1 0.1 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ00497.1 - 3.7e-06 27.2 24.5 0.39 11.5 0.0 9.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORZ00497.1 - 3.8e-05 23.2 7.2 0.013 14.9 0.1 3.9 2 2 0 3 3 3 2 MalT-like TPR region NARP1 PF12569.8 ORZ00497.1 - 7.7e-05 21.8 25.4 0.00012 21.2 0.0 5.1 2 2 4 6 6 5 2 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 ORZ00497.1 - 0.00048 20.1 1.5 0.33 10.8 0.0 3.6 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal SHNi-TPR PF10516.9 ORZ00497.1 - 0.0015 18.0 8.2 0.047 13.2 0.0 4.1 4 0 0 4 4 3 1 SHNi-TPR FAT PF02259.23 ORZ00497.1 - 0.0043 16.3 0.1 1.9 7.6 0.0 2.7 1 1 0 2 2 2 1 FAT domain ATP-synt_E PF05680.12 ORZ00497.1 - 0.015 15.6 6.1 0.015 15.6 6.1 2.1 2 0 0 2 2 1 0 ATP synthase E chain DUF4810 PF16068.5 ORZ00497.1 - 0.037 14.6 9.3 0.27 11.8 0.0 5.3 4 2 2 6 6 5 0 Domain of unknown function (DUF4810) PG_binding_4 PF12229.8 ORZ00497.1 - 0.043 14.1 0.1 0.84 9.9 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TPR_3 PF07720.12 ORZ00497.1 - 0.21 11.6 10.8 1.2 9.2 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TSGP1 PF07771.11 ORZ00497.1 - 0.25 11.5 2.8 0.15 12.2 0.9 1.6 2 0 0 2 2 1 0 Tick salivary peptide group 1 DUF3808 PF10300.9 ORZ00497.1 - 0.34 9.6 8.8 2.1 7.0 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3808) DUF4192 PF13830.6 ORZ00497.1 - 0.47 10.5 4.6 0.76 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) TPR_20 PF14561.6 ORZ00497.1 - 1.2 9.5 14.7 2.7 8.4 0.0 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 ORZ00497.1 - 1.4 7.6 4.1 1.4 7.5 2.8 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PMSI1 PF15322.6 ORZ00497.1 - 2.9 7.3 8.6 4.1 6.8 8.6 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Calpain_inhib PF00748.19 ORZ00497.1 - 3.8 8.0 15.7 12 6.4 15.7 1.8 1 0 0 1 1 1 0 Calpain inhibitor MAS20 PF02064.15 ORZ00497.1 - 6 7.0 15.0 47 4.1 0.0 4.9 4 2 1 5 5 5 0 MAS20 protein import receptor PDCD2_C PF04194.13 ORZ00497.1 - 6.5 6.8 7.2 30 4.7 3.2 2.9 3 0 0 3 3 3 0 Programmed cell death protein 2, C-terminal putative domain Mago_nashi PF02792.14 ORZ00498.1 - 1.2e-74 249.1 0.8 1.4e-74 249.0 0.8 1.0 1 0 0 1 1 1 1 Mago nashi protein HMG_box PF00505.19 ORZ00499.1 - 1.7e-18 66.8 1.3 1.7e-18 66.8 1.3 2.1 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ00499.1 - 8.9e-14 51.8 1.3 8.9e-14 51.8 1.3 2.2 2 0 0 2 2 2 1 HMG-box domain MlaC PF05494.12 ORZ00499.1 - 0.04 13.7 3.4 0.079 12.7 0.0 2.2 2 0 0 2 2 2 0 MlaC protein DUF2057 PF09829.9 ORZ00499.1 - 0.088 13.0 17.5 0.33 11.1 2.5 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) SNAPc19 PF15497.6 ORZ00499.1 - 0.14 12.6 16.5 1.6 9.3 5.0 2.9 2 1 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 LCD1 PF09798.9 ORZ00499.1 - 0.87 8.0 8.8 1.3 7.5 8.8 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Band_3_cyto PF07565.13 ORZ00499.1 - 1.2 8.9 9.6 2 8.1 3.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CCDC106 PF15794.5 ORZ00499.1 - 9.3 5.9 19.6 0.086 12.5 11.1 1.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 106 PIG-L PF02585.17 ORZ00500.1 - 1.8e-26 93.3 0.0 2.4e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase RNA_pol_Rpc4 PF05132.14 ORZ00501.1 - 3.5e-31 108.7 3.8 3.5e-31 108.7 3.8 3.2 3 0 0 3 3 3 1 RNA polymerase III RPC4 RLAN PF14401.6 ORZ00501.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain DUF3602 PF12223.8 ORZ00501.1 - 0.66 10.6 10.6 0.21 12.2 4.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) PTPRCAP PF15713.5 ORZ00501.1 - 4.2 7.7 10.4 0.72 10.1 2.8 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Prefoldin_2 PF01920.20 ORZ00502.1 - 2.5e-24 85.3 4.2 3e-24 85.0 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 ORZ00502.1 - 0.0002 21.0 5.0 0.0069 16.1 2.5 2.2 2 0 0 2 2 2 1 Septum formation initiator BLOC1_2 PF10046.9 ORZ00502.1 - 0.0013 19.0 5.8 0.057 13.7 2.7 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 XRCC4 PF06632.12 ORZ00502.1 - 0.0047 15.8 0.6 0.0047 15.8 0.6 1.9 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 TarS_C1 PF18674.1 ORZ00502.1 - 0.015 15.2 1.0 0.022 14.7 0.9 1.5 1 1 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 THOC7 PF05615.13 ORZ00502.1 - 0.02 15.2 1.5 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF5082 PF16888.5 ORZ00502.1 - 0.021 15.1 3.4 1.9 8.8 0.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) FliD_C PF07195.12 ORZ00502.1 - 0.034 13.6 0.6 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PI3K_P85_iSH2 PF16454.5 ORZ00502.1 - 0.042 13.5 9.2 1.2 8.7 9.2 2.1 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tup_N PF08581.10 ORZ00502.1 - 0.058 13.7 5.9 4 7.8 0.1 2.3 2 0 0 2 2 2 0 Tup N-terminal Thymidylate_kin PF02223.17 ORZ00502.1 - 0.058 13.1 0.7 0.1 12.3 0.1 1.6 2 0 0 2 2 2 0 Thymidylate kinase DivIVA PF05103.13 ORZ00502.1 - 0.075 13.1 7.3 0.19 11.8 0.3 2.5 1 1 2 3 3 3 0 DivIVA protein DUF2258 PF10015.9 ORZ00502.1 - 0.08 13.1 1.6 0.082 13.1 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) PRKG1_interact PF15898.5 ORZ00502.1 - 0.082 13.8 5.6 4.4 8.3 0.3 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain EHN PF06441.12 ORZ00502.1 - 0.099 13.0 1.1 0.18 12.2 0.4 1.7 1 1 1 2 2 2 0 Epoxide hydrolase N terminus DASH_Dam1 PF08653.10 ORZ00502.1 - 0.11 12.3 2.3 3.5 7.5 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 UPF0242 PF06785.11 ORZ00502.1 - 0.16 12.1 4.2 0.22 11.6 4.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4795 PF16043.5 ORZ00502.1 - 0.23 11.0 8.3 2 8.0 8.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PCRF PF03462.18 ORZ00502.1 - 0.28 11.0 6.4 0.54 10.1 6.4 1.4 1 1 0 1 1 1 0 PCRF domain JAKMIP_CC3 PF16034.5 ORZ00502.1 - 0.3 11.0 8.6 0.72 9.8 8.1 1.6 1 1 1 2 2 2 0 JAKMIP CC3 domain bZIP_1 PF00170.21 ORZ00502.1 - 0.35 11.0 6.8 0.87 9.7 1.8 2.2 2 0 0 2 2 2 0 bZIP transcription factor FAM167 PF11652.8 ORZ00502.1 - 0.44 11.1 7.6 0.9 10.1 0.8 2.3 1 1 1 2 2 2 0 FAM167 DUF4164 PF13747.6 ORZ00502.1 - 1.9 8.8 8.6 1.9 8.9 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) XhlA PF10779.9 ORZ00502.1 - 2.5 8.3 6.9 13 6.0 0.8 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF4140 PF13600.6 ORZ00502.1 - 3.4 8.2 5.7 8.4 6.9 0.8 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) F-box-like PF12937.7 ORZ00503.1 - 0.051 13.5 0.2 0.26 11.2 0.2 2.4 1 0 0 1 1 1 0 F-box-like FH2 PF02181.23 ORZ00504.1 - 1.3e-87 294.4 4.8 1.3e-87 294.4 4.8 2.7 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 ORZ00504.1 - 4.4e-46 157.0 0.8 4.4e-46 157.0 0.8 3.6 3 1 1 4 4 4 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 ORZ00504.1 - 1.6e-45 155.0 0.0 1.6e-45 155.0 0.0 2.7 3 1 1 4 4 4 1 Diaphanous GTPase-binding Domain RPM2 PF08579.11 ORZ00504.1 - 0.0055 17.1 0.5 7.2 7.0 0.0 3.4 3 0 0 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) GBP_C PF02841.14 ORZ00504.1 - 0.82 9.0 17.1 0.58 9.5 3.5 2.7 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF148 PF02520.17 ORZ00504.1 - 1.2 9.3 6.9 5.3 7.2 6.9 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 Gluconate_2-dh3 PF13618.6 ORZ00504.1 - 2 8.6 5.5 1.1 9.5 0.1 3.3 4 0 0 4 4 4 0 Gluconate 2-dehydrogenase subunit 3 AAA PF00004.29 ORZ00506.1 - 3e-15 56.8 0.0 1.1e-14 55.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORZ00506.1 - 3.2e-14 53.7 0.2 5.8e-11 43.1 0.0 2.9 2 1 1 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 ORZ00506.1 - 4.6e-11 43.2 0.0 2.8e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.11 ORZ00506.1 - 9.8e-11 41.5 0.2 2.4e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain Sigma54_activat PF00158.26 ORZ00506.1 - 7.8e-10 38.7 0.0 1.3e-07 31.5 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_lid_10 PF17872.1 ORZ00506.1 - 1.3e-06 28.4 0.4 3.6e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 ORZ00506.1 - 2.3e-06 27.6 0.1 9e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 ORZ00506.1 - 0.00015 21.3 0.0 0.002 17.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 ORZ00506.1 - 0.0002 21.7 1.7 0.0074 16.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 ORZ00506.1 - 0.00023 20.7 0.0 0.00054 19.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein PIF1 PF05970.14 ORZ00506.1 - 0.002 17.4 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase RuvB_N PF05496.12 ORZ00506.1 - 0.0022 17.8 0.1 0.19 11.5 0.0 2.5 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ORZ00506.1 - 0.0031 17.5 0.2 0.0093 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORZ00506.1 - 0.0093 16.0 0.0 0.038 14.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ORZ00506.1 - 0.011 15.6 0.0 0.085 12.8 0.0 2.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 ORZ00506.1 - 0.015 14.9 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 ORZ00506.1 - 0.015 14.6 0.3 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 ORZ00506.1 - 0.016 14.5 0.0 0.061 12.5 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.12 ORZ00506.1 - 0.023 14.0 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 ORZ00506.1 - 0.024 14.3 0.0 0.1 12.3 0.0 2.1 2 1 0 2 2 1 0 AAA domain TIP49 PF06068.13 ORZ00506.1 - 0.03 13.5 0.0 0.085 12.0 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain DUF815 PF05673.13 ORZ00506.1 - 0.038 13.2 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 ORZ00506.1 - 0.039 13.7 0.8 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ORZ00506.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.6 ORZ00506.1 - 0.066 13.3 0.0 2.2 8.4 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.14 ORZ00506.1 - 0.072 13.2 0.1 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORZ00506.1 - 0.18 11.5 0.6 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.6 ORZ00506.1 - 0.27 11.5 0.9 15 6.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_33 PF13671.6 ORZ00506.1 - 0.73 10.0 4.1 1.9 8.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ORZ00506.1 - 4 8.0 5.5 5.9 7.4 0.0 2.7 2 1 1 3 3 3 0 ABC transporter Pkinase PF00069.25 ORZ00507.1 - 2.8e-69 233.4 0.0 3.9e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.8 ORZ00507.1 - 3.1e-52 177.5 3.1 7.3e-49 166.4 0.8 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 ORZ00507.1 - 1.1e-42 146.2 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2443 PF10398.9 ORZ00507.1 - 0.0064 16.5 0.1 0.12 12.5 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2443) ABC1 PF03109.16 ORZ00507.1 - 0.025 14.7 0.6 0.12 12.6 0.4 2.2 1 1 1 2 2 2 0 ABC1 family Kinase-like PF14531.6 ORZ00507.1 - 0.032 13.5 0.0 1.3 8.3 0.0 2.9 2 1 0 2 2 2 0 Kinase-like CTP_transf_like PF01467.26 ORZ00508.1 - 9.2e-09 35.6 0.0 1.8e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like NADH-u_ox-rdase PF10785.9 ORZ00509.1 - 1.3e-32 112.3 0.2 1.8e-32 111.9 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 ORZ00509.1 - 6.3e-18 64.6 0.1 8.9e-18 64.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NDT80_PhoG PF05224.12 ORZ00510.1 - 6.6e-36 124.3 4.1 6.3e-35 121.1 0.0 3.2 2 2 0 2 2 2 1 NDT80 / PhoG like DNA-binding family SUIM_assoc PF16619.5 ORZ00510.1 - 0.019 15.0 6.9 0.019 15.0 6.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 ORZ00510.1 - 0.24 10.5 1.2 0.44 9.6 1.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein GAS2 PF02187.17 ORZ00511.1 - 2.4e-12 46.8 0.1 8.6e-12 45.0 0.1 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain dbPDZ_assoc PF16610.5 ORZ00511.1 - 0.093 13.0 1.1 0.43 10.8 1.1 2.2 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Atypical_Card PF18461.1 ORZ00511.1 - 0.23 11.7 1.2 1.9 8.8 0.6 3.1 2 0 0 2 2 2 0 Atypical caspase recruitment domain tRNA_SAD PF07973.14 ORZ00512.1 - 3.5e-08 33.4 0.4 6.9e-08 32.5 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 ORZ00512.1 - 9.8e-06 24.3 0.2 8.5e-05 21.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (A) DHHA1 PF02272.19 ORZ00512.1 - 0.0016 18.8 0.2 0.0033 17.8 0.2 1.5 1 0 0 1 1 1 1 DHHA1 domain DUF5323 PF17257.2 ORZ00512.1 - 0.11 12.4 1.2 10 6.1 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5323) CHRD PF07452.12 ORZ00512.1 - 0.16 12.9 0.1 0.71 10.9 0.1 2.1 2 0 0 2 2 2 0 CHRD domain Cyclin_N PF00134.23 ORZ00513.1 - 1.9e-07 30.8 0.1 0.00051 19.8 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin PF08613.11 ORZ00513.1 - 2.7e-06 27.8 0.1 2.7e-06 27.8 0.1 2.0 3 0 0 3 3 3 1 Cyclin SLM4 PF16818.5 ORZ00513.1 - 0.11 12.5 0.8 5 7.1 0.1 2.8 2 1 1 3 3 3 0 Protein SLM4 Transcrip_reg PF01709.20 ORZ00514.1 - 1e-77 260.8 0.7 1.2e-77 260.6 0.7 1.0 1 0 0 1 1 1 1 Transcriptional regulator Ribonuc_2-5A PF06479.12 ORZ00515.1 - 1.3e-42 145.0 0.3 2.2e-42 144.2 0.3 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 ORZ00515.1 - 1.9e-39 135.6 0.0 3.7e-38 131.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00515.1 - 5e-22 78.4 0.0 2.2e-20 73.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ00515.1 - 1.4e-06 27.4 0.0 2.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORZ00515.1 - 0.0003 20.2 0.0 0.00063 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORZ00515.1 - 0.063 12.9 0.1 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 ORZ00517.1 - 1.6e-16 60.2 0.0 3.4e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.22 ORZ00518.1 - 1.3e-05 24.9 0.0 0.0013 18.5 0.1 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 ORZ00518.1 - 0.036 14.3 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 BRCA1-associated protein 2 UCH PF00443.29 ORZ00519.1 - 4.1e-68 229.7 0.0 9.6e-68 228.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORZ00519.1 - 2.8e-22 79.7 0.0 1.6e-21 77.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 ORZ00519.1 - 4.8e-05 23.8 0.0 0.00014 22.3 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain USP8_dimer PF08969.11 ORZ00519.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_2 PF07724.14 ORZ00520.1 - 3e-37 128.4 0.0 7.5e-37 127.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 ORZ00520.1 - 2.3e-15 56.4 0.5 7.4e-15 54.8 0.1 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ORZ00520.1 - 8.5e-14 52.1 0.0 1.7e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORZ00520.1 - 8.9e-06 25.7 0.0 3.2e-05 24.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORZ00520.1 - 1.6e-05 24.4 0.1 0.0023 17.3 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ORZ00520.1 - 5.5e-05 23.5 0.4 0.0014 18.9 0.1 2.7 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 ORZ00520.1 - 0.00026 20.7 0.1 0.017 14.8 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 ORZ00520.1 - 0.00087 19.1 0.2 0.012 15.4 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ORZ00520.1 - 0.0012 18.4 0.0 0.0031 17.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 ORZ00520.1 - 0.0023 18.3 0.1 0.01 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 ORZ00520.1 - 0.0079 16.0 0.4 0.17 11.7 0.1 2.8 2 1 0 3 3 3 1 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.6 ORZ00520.1 - 0.0082 16.3 0.0 0.024 14.7 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORZ00520.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 ORZ00520.1 - 0.0087 16.1 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORZ00520.1 - 0.0096 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 ORZ00520.1 - 0.01 15.0 0.0 0.033 13.3 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain ABC_tran PF00005.27 ORZ00520.1 - 0.016 15.7 0.0 0.059 13.9 0.0 2.0 2 0 0 2 2 1 0 ABC transporter T2SSE PF00437.20 ORZ00520.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 ORZ00520.1 - 0.023 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORZ00520.1 - 0.025 14.3 0.0 0.08 12.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORZ00520.1 - 0.03 14.8 0.1 0.086 13.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORZ00520.1 - 0.033 14.3 1.5 0.079 13.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORZ00520.1 - 0.034 14.0 0.0 0.089 12.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_8 PF12780.7 ORZ00520.1 - 0.053 12.9 0.0 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 PhoH PF02562.16 ORZ00520.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 ORZ00520.1 - 0.11 11.6 0.0 0.51 9.5 0.0 2.1 2 1 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 ORZ00520.1 - 0.11 13.0 0.0 0.68 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 ORZ00520.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 ORZ00520.1 - 0.15 12.2 0.5 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain RNA_helicase PF00910.22 ORZ00520.1 - 0.19 12.1 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase WSD PF15613.6 ORZ00521.1 - 4.6e-24 84.8 0.4 4.6e-24 84.8 0.4 3.7 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 ORZ00521.1 - 4.5e-18 65.6 0.0 2.2e-17 63.4 0.0 2.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 ORZ00521.1 - 2.2e-12 47.1 0.3 4e-12 46.3 0.3 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 ORZ00521.1 - 0.0061 16.1 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 RNB PF00773.19 ORZ00522.1 - 3.8e-103 345.3 0.5 3.8e-103 345.3 0.5 1.6 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 ORZ00522.1 - 1.4e-19 69.9 0.0 3.5e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 ORZ00522.1 - 8.1e-15 54.6 0.6 2e-14 53.3 0.6 1.7 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 ORZ00522.1 - 4e-14 52.6 0.0 8.6e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 ORZ00522.1 - 4.3e-10 40.0 0.9 4.3e-10 40.0 0.9 2.2 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 ORZ00522.1 - 6.4e-09 35.9 3.7 2e-07 31.1 0.0 3.9 4 0 0 4 4 4 1 Cold shock domain OB_RNB PF08206.11 ORZ00522.1 - 0.0012 18.4 0.4 0.0043 16.7 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease B OB domain Dis3l2_C_term PF17877.1 ORZ00522.1 - 0.0041 17.4 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal PfkB PF00294.24 ORZ00523.1 - 3.1e-16 59.5 0.0 3.6e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORZ00523.1 - 0.00044 19.7 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MFS_1 PF07690.16 ORZ00524.1 - 9.8e-46 156.3 26.8 9.8e-46 156.3 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ00524.1 - 1.9e-06 27.1 18.0 1.9e-06 27.1 18.0 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ORZ00524.1 - 0.00011 20.7 1.7 0.00011 20.7 1.7 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector DUF521 PF04412.13 ORZ00524.1 - 0.046 12.4 0.1 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF521) Rick_17kDa_Anti PF05433.15 ORZ00524.1 - 0.083 12.8 0.6 0.21 11.5 0.6 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain OATP PF03137.20 ORZ00524.1 - 0.31 9.3 11.4 0.067 11.5 6.1 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DnaJ PF00226.31 ORZ00526.1 - 4.2e-16 58.8 0.1 4.2e-16 58.8 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain Plasmid_stab_B PF10784.9 ORZ00526.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Plasmid stability protein DUF2627 PF11118.8 ORZ00526.1 - 0.22 12.1 0.1 0.22 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) OAD_gamma PF04277.13 ORZ00526.1 - 3.6 8.3 6.1 11 6.7 0.0 3.4 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain RhoGEF PF00621.20 ORZ00527.1 - 1.5e-19 70.9 0.7 3.4e-19 69.8 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain SUIM_assoc PF16619.5 ORZ00527.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 4.7 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 BCAS3 PF12490.8 ORZ00528.1 - 1.6e-06 27.8 4.9 3.3e-05 23.5 0.3 2.5 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 3 WD40 PF00400.32 ORZ00528.1 - 2.7 9.0 5.0 1.4 9.9 0.5 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Mito_carr PF00153.27 ORZ00529.1 - 3.2e-51 171.2 2.4 4.1e-18 65.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RMI1_N PF08585.12 ORZ00530.1 - 0.00096 19.0 0.0 0.0057 16.4 0.0 1.8 1 1 1 2 2 2 1 RecQ mediated genome instability protein RMI1_N PF08585.12 ORZ00531.1 - 0.00014 21.7 0.0 0.00014 21.7 0.0 3.7 2 1 0 2 2 2 1 RecQ mediated genome instability protein IATP PF04568.12 ORZ00533.1 - 3.8e-08 33.6 4.1 4.8e-08 33.3 4.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP bZIP_1 PF00170.21 ORZ00533.1 - 0.0019 18.2 2.6 0.0025 17.9 2.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor TMCO5 PF14992.6 ORZ00533.1 - 0.0027 17.3 1.0 0.0027 17.3 1.0 1.0 1 0 0 1 1 1 1 TMCO5 family TEX13 PF15186.6 ORZ00533.1 - 0.012 15.3 4.8 0.013 15.1 4.8 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family SlyX PF04102.12 ORZ00533.1 - 0.023 15.3 4.2 0.027 15.1 4.2 1.2 1 0 0 1 1 1 0 SlyX WGG PF10273.9 ORZ00533.1 - 0.033 14.8 1.2 0.04 14.6 1.2 1.1 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 GP41 PF00517.17 ORZ00533.1 - 0.057 13.3 1.5 0.062 13.2 1.5 1.0 1 0 0 1 1 1 0 Retroviral envelope protein DUF4140 PF13600.6 ORZ00533.1 - 0.097 13.1 3.2 0.1 13.0 3.2 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 ORZ00533.1 - 0.12 12.8 1.4 0.18 12.2 1.4 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 ORZ00533.1 - 0.13 11.3 3.4 0.13 11.3 3.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Endonuc_Holl PF10107.9 ORZ00533.1 - 0.14 12.0 2.6 0.16 11.8 2.6 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DivIC PF04977.15 ORZ00533.1 - 0.23 11.3 7.4 0.31 10.9 7.4 1.2 1 0 0 1 1 1 0 Septum formation initiator Lzipper-MIP1 PF14389.6 ORZ00533.1 - 0.31 11.4 5.5 1.4 9.2 5.5 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 RIC3 PF15361.6 ORZ00533.1 - 0.32 11.4 2.7 0.21 12.0 1.7 1.3 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 bZIP_2 PF07716.15 ORZ00533.1 - 0.42 10.7 7.7 0.24 11.5 6.1 1.5 1 1 0 1 1 1 0 Basic region leucine zipper FlgM PF04316.13 ORZ00533.1 - 0.79 10.1 6.0 1.6 9.1 3.8 2.0 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM UDG PF03167.19 ORZ00534.1 - 2e-21 76.6 0.0 2.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Coatomer_E PF04733.14 ORZ00535.1 - 2.3e-82 276.7 7.1 2.7e-82 276.4 7.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 ORZ00535.1 - 4.8e-07 29.9 4.9 0.051 13.8 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORZ00535.1 - 4.8e-05 23.6 2.1 0.0075 16.5 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ00535.1 - 7.6e-05 23.1 11.2 0.02 15.4 0.2 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ORZ00535.1 - 0.00037 20.5 6.7 0.23 11.5 0.1 3.2 2 1 1 3 3 3 2 Putative TPR-like repeat TPR_14 PF13428.6 ORZ00535.1 - 0.0014 19.2 5.8 2.6 9.1 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ00535.1 - 0.0059 16.6 9.2 0.015 15.3 0.3 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ00535.1 - 0.02 14.6 0.1 0.44 10.3 0.2 2.7 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 ORZ00535.1 - 0.031 14.1 3.9 0.72 9.8 0.3 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORZ00535.1 - 0.053 13.9 0.2 25 5.3 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00535.1 - 0.092 13.4 4.5 2.5 8.8 0.4 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 ORZ00535.1 - 0.16 12.2 0.0 19 5.5 0.0 2.8 2 0 0 2 2 2 0 PPR repeat family TPR_10 PF13374.6 ORZ00535.1 - 1.1 9.3 5.2 13 5.9 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_32 PF13679.6 ORZ00536.1 - 2.1e-05 24.6 0.0 0.0001 22.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain zf-CCCH_2 PF14608.6 ORZ00536.1 - 0.012 16.1 1.8 0.012 16.1 1.8 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribosomal_L17 PF01196.19 ORZ00537.1 - 1.1e-35 122.4 0.0 2.2e-35 121.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 CCDC74_C PF14917.6 ORZ00537.1 - 0.06 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal Sgf11_N PF18519.1 ORZ00537.1 - 0.4 10.3 2.3 23 4.6 0.1 3.0 3 0 0 3 3 3 0 SAGA-associated factor 11 N-terminal domain GCV_T PF01571.21 ORZ00538.1 - 6.6e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SWIRM PF04433.17 ORZ00539.1 - 4.8e-29 100.5 0.0 1.1e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 ORZ00539.1 - 7.5e-25 86.7 8.3 7.5e-25 86.7 8.3 2.7 3 0 0 3 3 3 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 ORZ00539.1 - 7.4e-13 48.5 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORZ00539.1 - 4.5e-09 36.4 0.0 1.6e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORZ00539.1 - 0.00012 21.8 2.6 0.00027 20.7 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Zn_ribbon_2 PF12674.7 ORZ00539.1 - 0.0012 19.5 1.2 0.0062 17.2 1.2 2.3 1 0 0 1 1 1 1 Putative zinc ribbon domain Myb_DNA-bind_7 PF15963.5 ORZ00539.1 - 0.044 13.7 1.6 0.11 12.4 0.1 2.5 2 0 0 2 2 2 0 Myb DNA-binding like DUF4770 PF15994.5 ORZ00539.1 - 9.2 6.5 10.5 0.83 9.9 5.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) zf-C2H2 PF00096.26 ORZ00540.1 - 5.7e-11 42.2 22.5 0.0003 21.1 3.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ00540.1 - 1.3e-07 31.9 17.4 0.021 15.7 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORZ00540.1 - 3.4e-05 24.1 20.0 0.0031 17.9 0.7 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ00540.1 - 0.0014 18.6 1.9 0.0014 18.6 1.9 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger C1_4 PF07975.12 ORZ00540.1 - 0.0079 16.4 4.6 1 9.7 0.7 2.6 2 0 0 2 2 2 2 TFIIH C1-like domain NST1 PF13945.6 ORZ00540.1 - 0.12 12.4 14.3 0.27 11.3 14.3 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-met PF12874.7 ORZ00540.1 - 0.45 11.0 9.7 2 8.9 1.4 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RR_TM4-6 PF06459.12 ORZ00540.1 - 0.84 9.4 8.2 1.2 8.9 8.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 ORZ00540.1 - 1.1 7.9 9.8 1.5 7.5 9.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BNIP3 PF06553.12 ORZ00540.1 - 1.1 8.8 15.6 21 4.7 0.0 3.2 3 0 0 3 3 3 0 BNIP3 Macoilin PF09726.9 ORZ00540.1 - 1.3 7.5 10.7 1.7 7.1 10.7 1.1 1 0 0 1 1 1 0 Macoilin family zf-C2H2_jaz PF12171.8 ORZ00540.1 - 1.4 9.3 16.1 0.71 10.2 1.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORZ00540.1 - 1.4 9.2 9.1 1.2 9.5 4.3 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 ORZ00540.1 - 1.9 9.2 16.2 4.8 7.9 3.5 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats CDC45 PF02724.14 ORZ00540.1 - 3.5 5.8 19.5 5.4 5.2 19.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF629 PF04780.12 ORZ00540.1 - 5.3 5.5 14.5 0.25 9.8 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF629) Sod_Cu PF00080.20 ORZ00542.1 - 8.2e-33 113.6 0.5 1.5e-32 112.7 0.5 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 ORZ00542.1 - 3.2e-13 49.9 0.0 6.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain E1_dh PF00676.20 ORZ00543.1 - 9.8e-64 215.2 0.0 1.3e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 ORZ00543.1 - 4.9e-63 212.0 0.0 7.9e-63 211.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORZ00543.1 - 4.6e-53 179.0 0.0 1.2e-52 177.7 0.0 1.7 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 ORZ00543.1 - 2.1e-20 72.0 1.2 2.1e-20 72.0 1.2 1.7 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus PPR_3 PF13812.6 ORZ00544.1 - 3.3e-38 129.6 11.0 3e-10 40.0 0.1 7.0 4 3 4 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORZ00544.1 - 4.1e-33 114.6 9.7 7.2e-14 51.7 0.3 4.1 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 ORZ00544.1 - 1.4e-32 111.6 14.3 2.4e-06 27.7 1.8 7.9 2 2 7 9 9 9 9 PPR repeat family PPR PF01535.20 ORZ00544.1 - 4.7e-20 70.4 11.5 0.0028 17.8 0.3 9.6 11 1 0 11 11 11 4 PPR repeat PPR_1 PF12854.7 ORZ00544.1 - 4.5e-13 48.6 13.2 0.00094 18.8 0.3 7.4 8 1 0 8 8 8 3 PPR repeat Phage_ABA_S PF18066.1 ORZ00544.1 - 0.0034 18.1 1.6 13 6.6 0.1 4.3 4 1 1 5 5 5 1 Phage ABA sandwich domain RPM2 PF08579.11 ORZ00544.1 - 0.015 15.7 4.1 9.9 6.6 0.0 4.4 3 2 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) DUF5113 PF17140.4 ORZ00544.1 - 0.036 13.9 0.6 0.036 13.9 0.6 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) MSA-2c PF12238.8 ORZ00544.1 - 0.16 11.9 0.8 0.46 10.4 0.8 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c SUR7 PF06687.12 ORZ00546.1 - 3.7e-17 62.7 8.1 5e-17 62.2 8.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family ABC2_membrane_3 PF12698.7 ORZ00546.1 - 0.0061 15.7 1.9 0.0069 15.5 1.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Mem_trans PF03547.18 ORZ00546.1 - 0.31 9.4 4.9 0.39 9.1 4.9 1.1 1 0 0 1 1 1 0 Membrane transport protein B12D PF06522.11 ORZ00547.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Cyclin PF08613.11 ORZ00548.1 - 1.4e-29 103.5 0.9 2.1e-29 103.0 0.9 1.2 1 0 0 1 1 1 1 Cyclin ETF_QO PF05187.13 ORZ00550.1 - 2.7e-49 165.6 0.1 4.5e-49 164.9 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 ORZ00550.1 - 8.8e-09 35.4 1.1 0.00011 22.0 1.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORZ00550.1 - 2.4e-08 34.1 0.0 3.5e-07 30.4 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORZ00550.1 - 4.9e-08 32.5 0.6 1.2e-05 24.6 2.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ORZ00550.1 - 7.3e-07 28.7 0.0 8.4e-06 25.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 ORZ00550.1 - 1.4e-06 27.7 0.1 4.5e-06 26.1 0.2 1.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORZ00550.1 - 2.7e-06 27.0 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORZ00550.1 - 2.8e-06 27.8 0.6 0.12 13.0 0.7 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORZ00550.1 - 3.5e-05 23.8 0.3 0.00016 21.7 0.2 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORZ00550.1 - 4.4e-05 22.9 0.0 6.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 ORZ00550.1 - 0.00015 20.8 0.4 0.017 14.0 0.9 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 ORZ00550.1 - 0.0002 20.2 1.0 0.00032 19.5 1.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Fer4_7 PF12838.7 ORZ00550.1 - 0.00044 20.8 1.1 0.0011 19.6 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 ORZ00550.1 - 0.0014 17.8 0.4 0.0025 17.0 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORZ00550.1 - 0.0029 16.9 1.1 0.0046 16.2 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.6 ORZ00550.1 - 0.063 13.4 0.9 0.14 12.3 0.9 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Amino_oxidase PF01593.24 ORZ00550.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 ORZ00550.1 - 0.09 11.8 0.8 0.13 11.3 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 ORZ00550.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_9 PF13187.6 ORZ00550.1 - 0.14 12.3 0.8 0.34 11.1 0.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 ORZ00550.1 - 0.17 12.0 0.6 0.44 10.7 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain BSD PF03909.17 ORZ00551.1 - 2.1e-14 53.2 0.1 5e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 BSD domain PV-1 PF06637.11 ORZ00551.1 - 0.0058 15.5 0.3 0.01 14.7 0.3 1.4 1 0 0 1 1 1 1 PV-1 protein (PLVAP) UPF0225 PF17775.1 ORZ00551.1 - 0.57 11.0 3.4 0.57 11.0 1.2 2.2 2 0 0 2 2 2 0 UPF0225 domain 7TM_GPCR_Srsx PF10320.9 ORZ00552.1 - 0.0034 16.8 10.5 0.0068 15.8 10.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pkinase PF00069.25 ORZ00555.1 - 6.5e-50 169.9 0.0 9.6e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00555.1 - 5.9e-21 74.9 0.0 8.6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORZ00555.1 - 2e-06 27.9 0.0 5.5e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORZ00555.1 - 3.7e-05 22.8 0.0 0.001 18.1 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 ORZ00555.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORZ00555.1 - 0.0032 17.1 0.1 0.0093 15.6 0.1 1.9 1 1 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 ORZ00555.1 - 0.012 14.6 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 ORZ00555.1 - 0.087 12.4 0.1 0.087 12.4 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Piwi PF02171.17 ORZ00556.1 - 1.6e-107 359.2 0.0 2.5e-107 358.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORZ00556.1 - 1.1e-22 81.2 0.0 2.5e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 ORZ00556.1 - 1.9e-22 79.5 0.2 4.1e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 ORZ00556.1 - 1.2e-19 69.6 0.1 7e-19 67.2 0.1 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoMid PF16487.5 ORZ00556.1 - 1.8e-10 40.9 0.0 1.8e-10 40.9 0.0 2.5 3 0 0 3 3 3 1 Mid domain of argonaute ArgoL2 PF16488.5 ORZ00556.1 - 2.6e-09 37.3 1.9 5.7e-09 36.2 1.9 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain EF1_GNE PF00736.19 ORZ00558.1 - 5.9e-34 116.1 5.0 8.2e-34 115.7 1.6 2.2 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ORZ00558.1 - 7.6e-14 51.9 4.6 7.6e-14 51.9 4.6 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Polyketide_cyc2 PF10604.9 ORZ00558.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GST_C_3 PF14497.6 ORZ00558.1 - 0.016 15.4 0.3 0.046 13.9 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORZ00558.1 - 0.023 14.9 2.6 0.067 13.4 0.2 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 ORZ00558.1 - 0.041 14.4 0.5 0.063 13.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) FAM167 PF11652.8 ORZ00558.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 FAM167 DnaJ PF00226.31 ORZ00559.1 - 3.8e-16 59.0 0.2 1.1e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain DUF3871 PF12987.7 ORZ00559.1 - 0.078 11.8 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) Hormone_3 PF00159.18 ORZ00559.1 - 2.3 8.4 4.7 18 5.5 0.0 2.7 3 0 0 3 3 3 0 Pancreatic hormone peptide IML1 PF12257.8 ORZ00560.1 - 7.8e-117 389.5 0.1 1.6e-116 388.4 0.1 1.6 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 ORZ00560.1 - 7.9e-21 73.9 0.1 2e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AAA_33 PF13671.6 ORZ00560.1 - 0.2 11.8 1.2 7.5 6.7 0.0 3.2 3 1 0 4 4 4 0 AAA domain Citrate_synt PF00285.21 ORZ00561.1 - 5.4e-104 348.1 0.0 7.1e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FRB_dom PF08771.11 ORZ00561.1 - 0.039 14.4 0.1 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Eclosion PF04736.12 ORZ00561.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Eclosion hormone Cyclin PF08613.11 ORZ00563.1 - 6.5e-42 143.6 1.3 1.4e-41 142.6 1.3 1.5 1 1 0 1 1 1 1 Cyclin Mito_fiss_reg PF05308.11 ORZ00563.1 - 0.13 12.3 2.1 0.17 11.9 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 ORZ00563.1 - 0.17 12.0 3.5 0.26 11.3 3.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RAP1 PF07218.11 ORZ00563.1 - 0.81 7.9 3.1 1 7.6 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NUDE_C PF04880.13 ORZ00563.1 - 1.9 8.9 7.3 2.7 8.4 7.3 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region AF-4 PF05110.13 ORZ00563.1 - 2 6.4 6.6 2.2 6.3 6.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 ORZ00563.1 - 3.6 7.1 7.1 5 6.7 7.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 ORZ00564.1 - 3.6e-11 43.4 7.1 0.28 12.1 0.1 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00564.1 - 0.0061 16.8 0.0 4.4 7.7 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain 4HBT PF03061.22 ORZ00565.1 - 6.3e-06 26.4 0.0 8.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 ORZ00565.1 - 0.00046 19.6 0.1 0.00064 19.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 ORZ00565.1 - 0.00056 20.4 0.0 0.00072 20.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily VHS PF00790.19 ORZ00566.1 - 6.8e-38 129.7 1.1 1.3e-37 128.8 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 ORZ00566.1 - 1.4e-17 63.5 8.4 2.5e-17 62.7 8.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 ORZ00566.1 - 1.9e-07 30.5 7.3 0.0059 16.4 1.3 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 ORZ00566.1 - 0.00022 21.5 0.0 0.00068 19.9 0.0 1.9 1 0 0 1 1 1 1 GAT domain Hrs_helical PF12210.8 ORZ00566.1 - 0.00027 21.4 0.3 0.00094 19.7 0.0 2.0 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate ENTH PF01417.20 ORZ00566.1 - 0.0026 17.8 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain FYVE_2 PF02318.16 ORZ00566.1 - 0.0054 16.9 5.9 0.013 15.7 5.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 ORZ00566.1 - 0.12 12.4 10.1 2.5 8.2 0.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon OAD_gamma PF04277.13 ORZ00566.1 - 0.77 10.4 9.1 0.33 11.6 0.6 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Band_7 PF01145.25 ORZ00567.1 - 9.5e-23 81.1 1.9 1.3e-22 80.6 1.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 ORZ00567.1 - 0.1 12.7 0.3 0.56 10.3 0.3 2.1 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain DUF1378 PF07125.11 ORZ00567.1 - 0.19 11.9 0.8 22 5.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Glyco_transf_15 PF01793.16 ORZ00568.1 - 4.3e-113 377.9 10.0 5.3e-113 377.6 10.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3291 PF11695.8 ORZ00568.1 - 0.056 13.1 0.2 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) DAPDH_C PF16654.5 ORZ00568.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Hexapep PF00132.24 ORZ00569.1 - 5.2e-10 38.6 22.1 2.9e-06 26.8 4.1 4.7 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 ORZ00569.1 - 0.00043 19.3 0.6 0.00067 18.7 0.2 1.5 2 0 0 2 2 2 1 L-fucokinase Hexapep_2 PF14602.6 ORZ00569.1 - 0.00083 19.1 17.0 0.002 17.8 5.3 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase RhoGEF PF00621.20 ORZ00570.1 - 3.4e-35 121.9 0.0 6.1e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 ORZ00570.1 - 3.3e-05 24.4 0.5 7.6e-05 23.2 0.2 1.8 2 0 0 2 2 2 1 PH domain PPV_E1_N PF00524.18 ORZ00570.1 - 0.085 13.3 0.1 0.31 11.5 0.1 1.9 1 0 0 1 1 1 0 E1 Protein, N terminal domain PH_13 PF16652.5 ORZ00570.1 - 0.094 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Thiolase_N PF00108.23 ORZ00571.1 - 1.2e-19 70.8 0.0 4.3e-17 62.3 0.0 3.2 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORZ00571.1 - 6.1e-13 48.5 0.0 3.8e-12 45.9 0.0 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORZ00571.1 - 7.1e-05 22.5 2.7 0.0034 17.0 0.5 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORZ00571.1 - 0.00023 21.0 0.1 0.03 14.2 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 ORZ00571.1 - 0.00099 17.9 1.3 0.043 12.5 0.2 2.2 2 0 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 ORZ00571.1 - 0.002 18.1 0.1 0.26 11.3 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.6 ORZ00572.1 - 8.6e-63 212.0 0.7 1.1e-62 211.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORZ00572.1 - 4.1e-55 186.3 1.2 4.3e-55 186.2 0.4 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORZ00572.1 - 2.5e-15 56.8 1.4 3.3e-15 56.4 1.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORZ00572.1 - 4.4e-05 23.1 0.2 9.3e-05 22.0 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORZ00572.1 - 0.0014 18.2 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORZ00572.1 - 0.0038 17.1 0.5 0.0056 16.6 0.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORZ00572.1 - 0.0063 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 ORZ00572.1 - 0.0068 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_5 PF08323.11 ORZ00572.1 - 0.046 13.4 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain GDP_Man_Dehyd PF16363.5 ORZ00572.1 - 0.049 13.0 0.1 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_transf_4 PF13439.6 ORZ00572.1 - 0.09 12.8 0.0 0.97 9.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 DUF1776 PF08643.10 ORZ00572.1 - 0.16 11.4 0.0 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Ribonuc_red_sm PF00268.21 ORZ00572.1 - 0.24 10.8 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain ADH_N PF08240.12 ORZ00573.1 - 1.3e-30 105.4 0.1 2e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ00573.1 - 7.9e-16 58.2 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORZ00573.1 - 3.7e-10 39.7 0.0 9.4e-05 22.0 0.1 2.5 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORZ00573.1 - 1.2e-05 26.4 0.0 3.5e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase MTHFR_C PF12225.8 ORZ00573.1 - 0.013 15.2 1.5 0.023 14.4 1.5 1.3 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal UDPG_MGDP_dh_N PF03721.14 ORZ00573.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 ORZ00573.1 - 0.12 11.1 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 ORZ00573.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain E1-E2_ATPase PF00122.20 ORZ00574.1 - 1.2e-41 142.2 1.5 1.2e-41 142.2 1.5 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORZ00574.1 - 5.5e-24 85.6 0.7 1.5e-23 84.2 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ00574.1 - 1.6e-10 40.5 1.1 2.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ00574.1 - 0.015 15.0 0.0 0.05 13.3 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORZ00574.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2818 PF10993.8 ORZ00574.1 - 0.019 15.5 0.7 0.067 13.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) Epiglycanin_C PF14654.6 ORZ00574.1 - 1.9 8.6 3.8 0.56 10.3 0.3 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Pkinase PF00069.25 ORZ00575.1 - 4.7e-78 262.2 0.0 7.4e-78 261.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00575.1 - 2.7e-39 135.0 0.0 3.8e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 ORZ00575.1 - 1.6e-18 67.3 0.1 2e-14 54.1 0.1 2.6 1 1 1 2 2 2 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 ORZ00575.1 - 1.7e-08 34.2 0.0 5.5e-08 32.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like UBA_2 PF08587.11 ORZ00575.1 - 5.4e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 ORZ00575.1 - 0.00059 19.5 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORZ00575.1 - 0.0067 15.4 0.8 0.0097 14.9 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain KA1 PF02149.19 ORZ00575.1 - 0.012 15.3 0.0 0.39 10.5 0.0 2.7 2 0 0 2 2 2 0 Kinase associated domain 1 APH PF01636.23 ORZ00575.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.9 ORZ00575.1 - 0.021 13.6 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 ORZ00575.1 - 0.035 13.5 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 ORZ00576.1 - 2.1e-12 47.3 5.9 1.7e-07 31.8 2.2 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00576.1 - 0.00047 20.4 0.0 0.001 19.3 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ00576.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 ORZ00577.1 - 6.3e-24 84.3 0.2 1.8e-23 82.8 0.1 1.8 2 0 0 2 2 2 1 NLE (NUC135) domain WD40 PF00400.32 ORZ00577.1 - 4.5e-18 65.3 6.5 3.8e-05 24.4 0.7 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat HARP PF07443.13 ORZ00577.1 - 0.19 11.4 0.4 10 5.9 0.0 2.7 3 0 0 3 3 3 0 HepA-related protein (HARP) Spc24 PF08286.11 ORZ00578.1 - 4.1e-05 23.8 0.9 4.1e-05 23.8 0.9 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 ALS2CR11 PF15729.5 ORZ00578.1 - 0.019 14.1 1.3 0.021 14.0 1.3 1.0 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 DUF1664 PF07889.12 ORZ00578.1 - 0.058 13.4 3.0 0.071 13.2 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 ORZ00578.1 - 0.068 13.3 5.7 0.16 12.2 5.7 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 ORZ00578.1 - 0.15 11.4 10.0 0.27 10.5 9.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 ORZ00578.1 - 0.15 10.9 4.6 0.16 10.8 4.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Prefoldin_2 PF01920.20 ORZ00578.1 - 0.18 11.7 10.0 0.91 9.5 0.9 2.4 1 1 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 ORZ00578.1 - 0.3 10.9 7.7 0.42 10.4 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF720 PF05302.11 ORZ00578.1 - 0.36 10.7 4.8 0.65 9.9 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF720) Mito_fiss_reg PF05308.11 ORZ00578.1 - 0.39 10.8 5.4 0.6 10.2 5.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PACT_coil_coil PF10495.9 ORZ00578.1 - 0.57 10.8 3.4 5 7.8 0.2 2.3 1 1 1 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Swi5 PF07061.11 ORZ00578.1 - 1.2 9.3 7.1 4.1 7.6 4.5 2.4 1 1 1 2 2 2 0 Swi5 Spc7 PF08317.11 ORZ00578.1 - 3.6 6.4 13.6 11 4.7 13.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 ORZ00578.1 - 7.1 7.1 12.3 0.85 10.1 3.1 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 ORZ00578.1 - 8.8 6.9 19.5 1.6e+02 2.8 19.5 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 ORZ00578.1 - 9.3 6.6 8.5 4.5 7.6 1.0 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper TRAPP PF04051.16 ORZ00579.1 - 1.8e-47 160.7 0.0 2.1e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF5600 PF18150.1 ORZ00580.1 - 1.5e-38 131.7 3.0 3.1e-38 130.6 3.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 ORZ00580.1 - 4.2e-17 62.0 0.0 2.1e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 ORZ00580.1 - 2.3e-14 53.0 0.0 4.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 ORZ00580.1 - 5.2e-14 52.7 0.0 1.1e-12 48.3 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ORZ00580.1 - 2.5e-08 34.0 0.0 6.9e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORZ00580.1 - 3.9e-05 23.3 0.0 0.00028 20.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.32 ORZ00580.1 - 0.00019 20.7 0.1 0.00063 19.1 0.1 2.0 1 0 0 1 1 1 1 EF hand Roc PF08477.13 ORZ00580.1 - 0.00024 21.3 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORZ00580.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_6 PF13405.6 ORZ00580.1 - 0.0056 16.5 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain FeoB_N PF02421.18 ORZ00580.1 - 0.013 15.0 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 ORZ00580.1 - 0.046 13.3 0.2 6.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Ras family EF-hand_7 PF13499.6 ORZ00580.1 - 0.067 13.7 0.0 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair SRPRB PF09439.10 ORZ00580.1 - 0.086 12.3 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PGAP1 PF07819.13 ORZ00581.1 - 3.2e-05 23.8 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ORZ00581.1 - 0.00033 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 ORZ00581.1 - 0.00052 19.7 0.1 0.068 12.8 0.0 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORZ00581.1 - 0.0012 19.5 0.2 0.0017 19.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 ORZ00581.1 - 0.0023 17.8 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 ORZ00581.1 - 0.032 13.6 0.0 0.89 8.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RNA_polI_A34 PF08208.11 ORZ00582.1 - 1e-29 104.1 5.6 1.3e-29 103.8 5.6 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 ubiquitin PF00240.23 ORZ00583.1 - 2.3e-22 78.5 0.1 4.5e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORZ00583.1 - 2e-10 40.4 0.2 4.2e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORZ00583.1 - 2.8e-06 27.9 2.4 1.6e-05 25.4 0.1 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UBA PF00627.31 ORZ00583.1 - 4.1e-06 26.6 0.4 1.2e-05 25.1 0.4 1.9 1 0 0 1 1 1 1 UBA/TS-N domain TBK1_ULD PF18396.1 ORZ00583.1 - 0.00016 21.5 0.0 0.00016 21.5 0.0 1.9 2 0 0 2 2 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORZ00583.1 - 0.001 19.1 0.4 0.014 15.4 0.4 2.2 1 1 1 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORZ00583.1 - 0.0035 17.4 0.2 0.0035 17.4 0.2 2.3 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DMA PF03474.14 ORZ00583.1 - 0.0064 16.1 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 DMRTA motif DUF2722 PF10846.8 ORZ00583.1 - 0.0089 15.0 9.5 0.1 11.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) UBA_4 PF14555.6 ORZ00583.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Ubiquitin_5 PF18037.1 ORZ00583.1 - 0.034 14.5 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Spt20 PF12090.8 ORZ00583.1 - 0.038 13.6 18.6 0.18 11.4 3.9 2.2 2 0 0 2 2 2 0 Spt20 family CUE PF02845.16 ORZ00583.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 CUE domain Coilin_N PF15862.5 ORZ00583.1 - 0.081 12.7 0.3 0.081 12.7 0.3 2.6 2 1 0 2 2 2 0 Coilin N-terminus TFIIA PF03153.13 ORZ00583.1 - 0.18 11.7 23.1 1 9.2 2.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 ORZ00583.1 - 0.18 12.2 10.1 1.6 9.2 1.0 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Keratin_2_head PF16208.5 ORZ00583.1 - 0.25 11.5 22.3 0.038 14.1 18.4 1.6 2 0 0 2 2 2 0 Keratin type II head Suf PF05843.14 ORZ00583.1 - 0.46 10.4 16.5 1.5 8.8 5.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 ORZ00583.1 - 2.7 8.6 26.4 0.87 10.2 3.6 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2362 PF10154.9 ORZ00584.1 - 6.3e-61 206.9 26.5 3e-31 108.9 0.4 6.0 1 1 2 3 3 3 3 Uncharacterized conserved protein (DUF2362) UBA PF00627.31 ORZ00584.1 - 6.2e-08 32.4 1.2 1.3e-07 31.4 1.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Cyclin PF08613.11 ORZ00585.1 - 1.1e-12 48.6 0.8 1.1e-12 48.6 0.8 3.0 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 ORZ00585.1 - 1.4e-07 31.3 0.2 2.3e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain UNC-50 PF05216.13 ORZ00587.1 - 0.012 15.1 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 UNC-50 family TM231 PF10149.9 ORZ00587.1 - 1.1 8.5 3.6 1.3 8.3 3.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 231 Polysacc_deac_1 PF01522.21 ORZ00588.1 - 2.1e-32 111.6 0.0 4.8e-32 110.5 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORZ00588.1 - 7.8e-05 22.0 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Ribosomal_60s PF00428.19 ORZ00588.1 - 4.3 8.0 15.9 1.8 9.2 5.8 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein RAP1 PF07218.11 ORZ00588.1 - 9.1 4.4 10.7 12 4.0 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-met2 PF12907.7 ORZ00589.1 - 2.3e-18 66.0 4.6 3.9e-18 65.3 4.6 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 ORZ00589.1 - 9.7e-06 26.4 14.4 4.4e-05 24.3 9.6 2.1 2 0 0 2 2 2 2 4F5 protein family PMT PF02366.18 ORZ00590.1 - 3.2e-73 246.3 13.0 3.2e-73 246.3 13.0 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORZ00590.1 - 3.1e-60 203.2 12.3 7.8e-60 201.9 12.3 1.7 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORZ00590.1 - 2.2e-31 109.2 0.1 4.8e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 ORZ00590.1 - 0.0015 18.7 11.0 0.0015 18.7 11.0 2.9 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase OrfB_Zn_ribbon PF07282.11 ORZ00591.1 - 0.0029 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain SH3BGR PF04908.15 ORZ00593.1 - 3.1e-13 49.7 0.7 1.6e-12 47.5 0.7 2.2 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 ORZ00593.1 - 5.2e-09 36.2 0.0 1.6e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin Flg_hook PF02120.16 ORZ00593.1 - 0.0055 16.6 3.6 0.055 13.4 0.4 2.6 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK DAGK_cat PF00781.24 ORZ00593.1 - 0.088 12.4 0.1 0.088 12.4 0.1 2.7 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain ERM PF00769.19 ORZ00593.1 - 0.49 10.2 18.8 0.75 9.6 18.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Bud13 PF09736.9 ORZ00593.1 - 0.6 10.5 11.7 0.55 10.6 8.8 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex XhlA PF10779.9 ORZ00593.1 - 1.7 8.9 7.4 0.74 10.1 0.7 2.6 2 0 0 2 2 2 0 Haemolysin XhlA TBCC_N PF16752.5 ORZ00593.1 - 2.2 8.8 13.2 1.2 9.6 10.2 2.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF1640 PF07798.11 ORZ00593.1 - 2.6 8.0 16.1 0.63 10.1 11.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) RNA_polI_A14 PF08203.11 ORZ00593.1 - 7.7 7.3 8.6 1.8 9.3 4.6 2.0 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 CP_ATPgrasp_2 PF14403.6 ORZ00596.1 - 0.035 13.0 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Ceramidase PF05875.12 ORZ00597.1 - 3e-89 299.0 16.4 3.6e-89 298.7 16.4 1.0 1 0 0 1 1 1 1 Ceramidase p53-inducible11 PF14936.6 ORZ00597.1 - 0.11 12.6 1.6 0.16 12.1 1.6 1.4 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 Leader_Trp PF08255.11 ORZ00597.1 - 3.9 7.7 7.4 0.13 12.2 1.1 2.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide YIF1 PF03878.15 ORZ00598.1 - 1.4e-88 296.5 0.9 1.4e-88 296.5 0.9 1.5 2 0 0 2 2 2 1 YIF1 UNC-93 PF05978.16 ORZ00598.1 - 0.048 13.4 0.2 0.048 13.4 0.2 1.7 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 GDI PF00996.18 ORZ00599.1 - 1.3e-61 208.5 0.0 2.5e-47 161.4 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 ORZ00599.1 - 0.068 13.4 0.1 0.24 11.6 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Exonuc_X-T_C PF08411.10 ORZ00599.1 - 0.086 12.0 0.2 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Exonuclease C-terminal Lyase_1 PF00206.20 ORZ00600.1 - 1.5e-121 405.6 0.0 2.1e-121 405.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ORZ00600.1 - 5.4e-25 87.6 0.0 1.3e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus PilA4 PF18682.1 ORZ00600.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Pilin A4 GFA PF04828.14 ORZ00601.1 - 1.4e-09 38.2 1.1 1.4e-09 38.2 1.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 ORZ00601.1 - 0.019 14.8 0.3 0.019 14.8 0.3 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_ribbon_SprT PF17283.2 ORZ00601.1 - 0.35 10.8 10.6 1.6 8.7 4.5 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain AMP-binding PF00501.28 ORZ00602.1 - 7.7e-101 337.7 0.0 1.1e-100 337.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ00602.1 - 0.11 13.5 0.1 0.4 11.7 0.1 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain VWA_2 PF13519.6 ORZ00603.1 - 3e-26 92.1 2.0 6.7e-26 91.0 0.3 2.4 3 1 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 ORZ00603.1 - 1.2e-10 41.9 1.6 1.2e-10 41.9 1.6 1.8 2 1 1 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 ORZ00603.1 - 1.7e-07 30.7 20.7 0.0044 16.8 1.6 4.2 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.14 ORZ00603.1 - 2.1e-07 30.9 0.8 5.1e-07 29.7 0.2 1.8 2 0 0 2 2 2 1 Ssl1-like CTP_synth_N PF06418.14 ORZ00604.1 - 1.2e-125 418.2 0.0 1.5e-125 417.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ORZ00604.1 - 4.6e-61 205.9 0.0 7.4e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORZ00604.1 - 7.8e-06 25.8 0.1 5.2e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 ORZ00604.1 - 0.031 14.3 0.0 0.087 12.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MoaE PF02391.17 ORZ00608.1 - 8.5e-39 132.3 0.2 9.5e-39 132.2 0.2 1.0 1 0 0 1 1 1 1 MoaE protein tRNA-synt_2 PF00152.20 ORZ00609.1 - 2.2e-94 316.1 0.0 3.6e-94 315.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORZ00609.1 - 1.4e-09 37.8 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 ORZ00609.1 - 0.028 14.1 4.6 0.096 12.3 4.6 1.8 1 1 0 1 1 1 0 tRNA_anti-like RR_TM4-6 PF06459.12 ORZ00609.1 - 0.039 13.8 5.7 0.066 13.0 5.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3684 PF12449.8 ORZ00609.1 - 0.06 11.1 4.8 0.077 10.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Ribosomal_L22 PF00237.19 ORZ00609.1 - 0.16 12.2 3.7 18 5.6 3.1 2.9 3 0 0 3 3 3 0 Ribosomal protein L22p/L17e DUF16 PF01519.16 ORZ00609.1 - 0.25 11.8 5.9 0.56 10.7 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Methyltransf_15 PF09445.10 ORZ00610.1 - 2.6e-43 147.5 0.0 3.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 ORZ00610.1 - 1.3e-07 32.2 0.0 3.7e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORZ00610.1 - 2.2e-06 27.4 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 ORZ00610.1 - 4.1e-06 26.7 0.0 5.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 ORZ00610.1 - 4.6e-06 26.5 0.0 6.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ORZ00610.1 - 4.9e-06 26.4 0.1 3.1e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 ORZ00610.1 - 0.00064 19.2 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORZ00610.1 - 0.00093 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORZ00610.1 - 0.0012 19.4 0.0 0.0028 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORZ00610.1 - 0.0024 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORZ00610.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase N6_N4_Mtase PF01555.18 ORZ00610.1 - 0.038 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_2 PF00891.18 ORZ00610.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain tRNA_U5-meth_tr PF05958.11 ORZ00610.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase ThrE PF06738.12 ORZ00611.1 - 1.9e-51 174.8 13.3 4.6e-47 160.4 0.4 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORZ00611.1 - 2.2e-06 27.9 25.9 2.9e-06 27.4 7.6 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Nucleo_P87 PF07267.11 ORZ00611.1 - 0.56 9.0 6.5 0.8 8.5 6.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Carboxyl_trans PF01039.22 ORZ00612.1 - 4.6e-114 381.8 0.1 5.7e-114 381.5 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Nebulin PF00880.18 ORZ00612.1 - 0.44 10.5 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Nebulin repeat F-box-like PF12937.7 ORZ00613.1 - 1.7e-10 40.6 0.1 3.6e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ00613.1 - 1.5e-08 34.3 0.1 3.5e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 ORZ00613.1 - 0.00039 21.2 2.5 0.34 11.9 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat Pcc1 PF09341.10 ORZ00614.1 - 2.5e-22 78.8 0.7 2.8e-22 78.6 0.7 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 PGI PF00342.19 ORZ00615.1 - 2.3e-255 847.7 0.2 2.6e-255 847.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Polysacc_deac_1 PF01522.21 ORZ00616.1 - 2.1e-34 118.1 0.1 3.4e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase LigB PF02900.18 ORZ00617.1 - 1.6e-32 112.6 0.0 2.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sulfotransfer_4 PF17784.1 ORZ00618.1 - 5.1e-64 216.0 0.0 5.9e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORZ00618.1 - 1e-05 26.1 1.2 7.5e-05 23.2 0.1 2.6 1 1 1 2 2 2 1 Sulfotransferase family Carb_kinase PF01256.17 ORZ00618.1 - 0.11 12.0 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate kinase PHD PF00628.29 ORZ00619.1 - 7.2e-09 35.4 15.6 1.3e-08 34.5 15.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 ORZ00619.1 - 0.0063 16.9 8.0 0.0063 16.9 8.0 3.2 3 0 0 3 3 3 1 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 ORZ00619.1 - 0.014 14.9 9.6 0.024 14.2 9.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 ORZ00619.1 - 0.016 15.2 5.3 0.037 14.1 5.3 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Popeye PF04831.13 ORZ00620.1 - 0.093 12.9 2.1 0.082 13.1 1.0 1.5 1 1 0 1 1 1 0 Popeye protein conserved region Rhomboid PF01694.22 ORZ00621.1 - 3.6e-31 108.2 13.3 3.6e-31 108.2 13.3 1.8 2 0 0 2 2 2 1 Rhomboid family TMEM43 PF07787.12 ORZ00621.1 - 4.2 6.7 5.1 2.3 7.5 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 43 CPP1-like PF11833.8 ORZ00621.1 - 6.6 6.3 9.9 1.2 8.7 1.8 2.2 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sod_Cu PF00080.20 ORZ00622.1 - 9.8e-45 152.2 4.5 1.1e-44 152.0 4.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Rop PF01815.16 ORZ00622.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Rop protein MT-A70 PF05063.14 ORZ00623.1 - 9.7e-39 133.0 0.0 1.5e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 MT-A70 ASF1_hist_chap PF04729.13 ORZ00624.1 - 7.7e-70 233.8 0.1 9.2e-70 233.5 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Atg14 PF10186.9 ORZ00625.1 - 0.0011 18.1 1.5 0.0011 18.1 1.5 2.4 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 ORZ00625.1 - 0.05 12.8 33.6 0.028 13.6 30.2 2.2 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Cas6b_C PF17262.2 ORZ00625.1 - 0.06 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Cas6b C-terminal domain JIP_LZII PF16471.5 ORZ00625.1 - 0.096 12.9 9.6 1.3 9.3 0.2 3.8 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Fib_alpha PF08702.10 ORZ00625.1 - 3.4 7.8 16.1 1.1 9.4 1.1 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 ORZ00625.1 - 5.2 7.4 16.7 0.37 11.1 4.7 3.3 2 1 1 3 3 3 0 Tup N-terminal APG6_N PF17675.1 ORZ00625.1 - 8.3 6.9 35.8 30 5.1 20.0 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region Helicase_C PF00271.31 ORZ00626.1 - 5.7e-15 55.6 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORZ00626.1 - 5.8e-09 36.0 0.1 2.1e-08 34.2 0.0 2.0 2 1 1 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.10 ORZ00626.1 - 1.1e-05 25.1 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 ORZ00626.1 - 1.6e-05 25.5 0.2 3.5e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Osmo_CC PF08946.10 ORZ00626.1 - 0.001 19.2 1.5 0.0027 17.9 1.5 1.6 1 0 0 1 1 1 1 Osmosensory transporter coiled coil ORF45 PF17620.2 ORZ00626.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function G-gamma PF00631.22 ORZ00627.1 - 3.4e-19 68.6 0.1 4.1e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 GGL domain RL10P_insert PF17777.1 ORZ00629.1 - 2.2e-23 82.0 0.0 3.3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 ORZ00629.1 - 7.9e-22 77.3 0.1 1.2e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Myb_DNA-binding PF00249.31 ORZ00630.1 - 6.8e-13 48.6 2.6 5.5e-06 26.5 0.9 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORZ00630.1 - 9.3e-12 45.0 1.4 4.6e-07 30.0 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORZ00630.1 - 0.043 14.2 3.6 0.13 12.6 1.3 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain FliM PF02154.15 ORZ00630.1 - 0.07 13.0 0.0 0.084 12.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar motor switch protein FliM HATPase_c PF02518.26 ORZ00631.1 - 1.4e-29 102.9 0.0 2.4e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORZ00631.1 - 1.4e-25 89.6 0.6 6.1e-24 84.4 0.1 2.7 2 0 0 2 2 2 1 Response regulator receiver domain Pkinase_Tyr PF07714.17 ORZ00631.1 - 2.2e-23 82.9 0.0 4.7e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORZ00631.1 - 2.5e-21 76.3 0.0 5.9e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HisKA PF00512.25 ORZ00631.1 - 2e-16 59.8 0.0 2e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Rootletin PF15035.6 ORZ00631.1 - 0.013 15.6 3.1 0.031 14.3 3.1 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HATPase_c_3 PF13589.6 ORZ00631.1 - 0.024 14.5 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ephrin_rec_like PF07699.13 ORZ00631.1 - 0.11 12.3 16.2 0.049 13.4 12.8 2.2 2 1 0 2 2 2 0 Putative ephrin-receptor like AAA_13 PF13166.6 ORZ00631.1 - 0.16 10.5 1.0 0.29 9.7 1.0 1.3 1 0 0 1 1 1 0 AAA domain DUF390 PF04094.14 ORZ00631.1 - 1.6 6.9 7.2 2.8 6.1 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) EF1G PF00647.19 ORZ00632.1 - 6.7e-49 164.4 0.2 2e-48 162.9 0.2 1.9 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 ORZ00632.1 - 3.3e-14 53.0 0.0 1.9e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORZ00632.1 - 3.2e-11 43.3 1.5 3.5e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORZ00632.1 - 2.3e-06 27.5 0.0 7.1e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORZ00632.1 - 0.00016 21.8 0.0 0.00049 20.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORZ00632.1 - 0.0013 19.1 0.0 0.0032 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ORZ00632.1 - 0.0033 17.2 0.1 0.0063 16.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAM91_C PF14648.6 ORZ00632.1 - 0.062 12.1 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 FAM91 C-terminus OAD_gamma PF04277.13 ORZ00632.1 - 0.91 10.2 3.4 2.4 8.8 3.4 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Fungal_trans PF04082.18 ORZ00633.1 - 1.7e-05 24.0 0.4 2.5e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PaaX_C PF08223.11 ORZ00633.1 - 0.014 15.6 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain PhoR PF11808.8 ORZ00633.1 - 1.3 9.4 4.6 18 5.8 0.2 3.7 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR Zn_clus PF00172.18 ORZ00634.1 - 3.1e-06 27.2 10.6 9.1e-06 25.7 10.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4203 PF13886.6 ORZ00635.1 - 6.7e-39 133.7 38.4 7.7e-39 133.5 38.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) OppC_N PF12911.7 ORZ00635.1 - 0.078 13.0 0.6 0.078 13.0 0.6 4.5 4 2 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Hexokinase_2 PF03727.16 ORZ00636.1 - 1.4e-82 276.7 0.0 2e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORZ00636.1 - 1.2e-67 227.7 0.0 1.6e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Complex1_LYR PF05347.15 ORZ00637.1 - 3.5e-08 33.4 4.1 5.9e-08 32.6 4.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORZ00637.1 - 0.0015 19.3 3.5 0.0021 18.7 3.6 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 ORZ00637.1 - 0.0027 18.2 1.6 0.0039 17.7 1.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Sel1 PF08238.12 ORZ00638.1 - 1.1e-28 99.0 21.1 2e-06 28.3 0.0 7.1 7 1 1 8 8 8 5 Sel1 repeat CCER1 PF15482.6 ORZ00638.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 TPR_7 PF13176.6 ORZ00638.1 - 0.73 10.0 3.7 19 5.5 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat SKA2 PF16740.5 ORZ00640.1 - 0.0022 17.8 3.6 0.0035 17.1 2.2 1.9 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 CENP-F_leu_zip PF10473.9 ORZ00640.1 - 0.0022 18.0 5.5 0.15 12.1 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 ORZ00640.1 - 0.17 12.0 7.4 0.26 11.4 5.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 ORZ00640.1 - 0.17 10.7 5.2 0.32 9.8 2.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 ORZ00640.1 - 0.64 10.1 4.6 3.1 7.9 4.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAP1_N PF04849.13 ORZ00640.1 - 0.86 8.7 6.1 2.5 7.2 6.0 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region FliJ PF02050.16 ORZ00640.1 - 1.2 9.3 6.3 1.4 9.2 0.8 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein Copper-fist PF00649.18 ORZ00641.1 - 3.7e-20 71.1 1.4 1.2e-19 69.5 1.4 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain Gln_deamidase_2 PF18626.1 ORZ00641.1 - 0.14 12.4 1.3 0.31 11.3 0.7 1.8 1 1 0 1 1 1 0 Glutaminase Spt20 PF12090.8 ORZ00641.1 - 0.42 10.2 13.1 2 8.0 8.8 2.3 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 ORZ00641.1 - 0.64 10.0 14.6 0.54 10.2 10.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 ORZ00642.1 - 6.4e-62 209.3 0.0 9.5e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00642.1 - 2.9e-31 108.7 0.0 3.9e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ00642.1 - 9e-10 38.3 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORZ00642.1 - 0.00036 20.5 0.4 0.0014 18.6 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORZ00642.1 - 0.0017 17.8 0.9 0.003 16.9 0.9 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORZ00642.1 - 0.0057 15.5 0.3 0.013 14.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 ORZ00642.1 - 0.022 13.7 0.0 0.022 13.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain MutS_V PF00488.21 ORZ00643.1 - 1.7e-43 148.9 1.4 2.7e-42 145.0 1.4 2.2 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORZ00643.1 - 4e-22 79.4 0.2 3.7e-21 76.2 0.0 2.6 3 1 0 3 3 3 1 MutS domain III AAA_25 PF13481.6 ORZ00643.1 - 0.08 12.5 0.2 3.5 7.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain RVT_connect PF06815.13 ORZ00643.1 - 0.18 12.1 0.0 0.73 10.1 0.0 2.0 1 0 0 1 1 1 0 Reverse transcriptase connection domain ADH_N PF08240.12 ORZ00644.1 - 1.6e-21 76.2 3.7 2.3e-21 75.7 3.7 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ00644.1 - 1.4e-18 67.1 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ00644.1 - 0.00028 21.9 0.0 0.00061 20.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORZ00644.1 - 0.00048 19.5 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORZ00644.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORZ00644.1 - 0.065 13.1 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 ORZ00644.1 - 0.11 11.8 0.7 0.19 11.1 0.2 1.5 1 1 0 1 1 1 0 ThiF family p450 PF00067.22 ORZ00645.1 - 6.5e-76 255.9 0.0 8.3e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 ORZ00646.1 - 3.9e-52 176.2 0.1 4.8e-39 133.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ00646.1 - 4.6e-09 35.9 0.1 1.2e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 ORZ00646.1 - 7.7e-08 32.0 0.2 9.1e-07 28.6 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 ORZ00646.1 - 7.8e-08 32.7 0.0 0.00054 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 ORZ00646.1 - 3.9e-07 30.3 0.2 0.00024 21.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORZ00646.1 - 6.3e-07 28.9 0.2 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 ORZ00646.1 - 7.7e-07 29.7 2.5 0.036 14.4 0.1 3.4 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 ORZ00646.1 - 1.1e-06 28.5 0.1 0.013 15.3 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORZ00646.1 - 1.3e-06 28.5 0.0 0.0015 18.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORZ00646.1 - 1.8e-06 27.5 0.2 0.0024 17.3 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORZ00646.1 - 1.7e-05 25.0 0.0 0.36 11.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 ORZ00646.1 - 2e-05 23.9 1.1 0.61 9.2 0.1 3.4 2 1 1 3 3 3 2 NB-ARC domain TsaE PF02367.17 ORZ00646.1 - 2.3e-05 24.4 0.0 0.41 10.6 0.0 2.7 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 ORZ00646.1 - 2.8e-05 23.9 0.1 0.042 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORZ00646.1 - 5.4e-05 23.0 0.0 0.22 11.3 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 ORZ00646.1 - 6.1e-05 23.4 0.0 0.077 13.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 ORZ00646.1 - 6.6e-05 23.4 0.0 0.49 10.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 ORZ00646.1 - 9.3e-05 22.0 0.2 0.099 12.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 ORZ00646.1 - 0.00012 22.6 0.0 0.025 15.1 0.0 2.9 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 ORZ00646.1 - 0.00015 21.7 1.3 0.047 13.6 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 ORZ00646.1 - 0.00019 21.2 0.2 0.056 13.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain CDC48_N PF02359.18 ORZ00646.1 - 0.00036 20.7 0.0 0.0016 18.6 0.0 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_14 PF13173.6 ORZ00646.1 - 0.00044 20.3 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 ORZ00646.1 - 0.00069 19.1 0.1 0.58 9.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ATPase PF06745.13 ORZ00646.1 - 0.00096 18.6 0.2 0.084 12.2 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 ORZ00646.1 - 0.0037 16.9 3.2 2.8 7.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain ATPase_2 PF01637.18 ORZ00646.1 - 0.0046 16.9 0.4 18 5.1 0.0 3.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ResIII PF04851.15 ORZ00646.1 - 0.013 15.5 0.0 3.5 7.6 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORZ00646.1 - 0.014 15.2 0.0 0.8 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORZ00646.1 - 0.017 14.3 0.2 0.33 10.1 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 ORZ00646.1 - 0.017 14.2 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.11 ORZ00646.1 - 0.017 14.9 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORZ00646.1 - 0.02 15.2 0.0 0.9 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 ORZ00646.1 - 0.022 14.6 1.1 4.3 7.1 0.2 3.9 2 2 1 4 4 4 0 DEAD/DEAH box helicase IPT PF01745.16 ORZ00646.1 - 0.026 13.9 0.2 0.74 9.2 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 ORZ00646.1 - 0.032 13.5 0.1 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 ORZ00646.1 - 0.038 13.2 0.9 8.9 5.4 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 ORZ00646.1 - 0.042 14.1 0.1 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORZ00646.1 - 0.081 12.7 0.2 5 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 ORZ00646.1 - 0.091 12.5 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 ORZ00646.1 - 0.12 12.2 0.1 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 ORZ00646.1 - 0.13 11.3 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PRMT5 PF05185.16 ORZ00647.1 - 2.4e-68 229.4 0.0 3.9e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 ORZ00647.1 - 1.1e-54 185.4 0.2 1.5e-54 184.9 0.2 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 ORZ00647.1 - 1e-53 181.8 1.8 1.6e-53 181.2 1.8 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 ORZ00647.1 - 0.00054 20.6 0.0 0.0013 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ORZ00647.1 - 0.0048 16.7 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Tmemb_170 PF10190.9 ORZ00648.1 - 1.3e-10 41.6 11.0 1.6e-10 41.3 11.0 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 IBV_3C PF03620.13 ORZ00648.1 - 1.5 9.4 6.0 0.85 10.1 0.4 2.1 1 1 1 2 2 2 0 IBV 3C protein MgtC PF02308.16 ORZ00649.1 - 6.9 7.1 9.6 0.23 11.8 2.0 2.2 2 1 0 2 2 2 0 MgtC family MHYT PF03707.16 ORZ00650.1 - 4.5e-23 81.2 29.0 3.1e-10 40.1 2.2 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Methyltransf_25 PF13649.6 ORZ00651.1 - 1.1e-08 35.6 0.0 2.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ00651.1 - 3.3e-08 34.0 0.0 7.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ00651.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ00651.1 - 3e-05 23.9 0.0 7.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ00651.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TrbI_Ftype PF09677.10 ORZ00651.1 - 0.028 14.7 0.1 0.056 13.8 0.1 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Methyltransf_12 PF08242.12 ORZ00651.1 - 0.039 14.7 0.0 0.14 12.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain EI24 PF07264.11 ORZ00652.1 - 1.1e-11 45.3 0.3 3.6e-10 40.4 0.3 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Promethin PF16015.5 ORZ00652.1 - 0.0039 17.1 4.6 1.9 8.4 0.0 3.2 3 0 0 3 3 3 2 Promethin DUF2109 PF09882.9 ORZ00652.1 - 0.35 10.9 3.1 0.82 9.7 0.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Pollen_allerg_2 PF01620.16 ORZ00654.1 - 0.24 11.6 8.2 0.031 14.5 3.0 2.1 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) BolA PF01722.18 ORZ00656.1 - 6.3e-19 68.0 0.1 1.7e-18 66.6 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein RsfS PF02410.15 ORZ00656.1 - 0.032 14.7 0.0 0.039 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation Malic_M PF03949.15 ORZ00657.1 - 6.1e-89 297.7 0.0 7.9e-89 297.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORZ00657.1 - 3e-72 242.2 0.0 7.8e-72 240.9 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Humanin PF15040.6 ORZ00658.1 - 0.021 14.3 1.3 0.072 12.5 0.9 2.0 2 0 0 2 2 2 0 Humanin family PPR_2 PF13041.6 ORZ00659.1 - 2.4e-21 75.7 0.2 0.00024 21.2 0.0 6.7 4 1 2 6 6 6 6 PPR repeat family PPR_3 PF13812.6 ORZ00659.1 - 3.4e-15 55.9 0.0 0.0069 16.4 0.0 7.4 4 3 4 8 8 8 5 Pentatricopeptide repeat domain PPR_long PF17177.4 ORZ00659.1 - 5.4e-13 48.8 0.9 0.00048 19.6 0.1 3.6 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORZ00659.1 - 2.4e-09 36.8 4.8 0.18 12.1 0.1 6.5 7 0 0 7 7 7 4 PPR repeat PPR_1 PF12854.7 ORZ00659.1 - 0.0064 16.2 0.0 12 5.7 0.1 4.7 5 0 0 5 5 5 1 PPR repeat Ribosomal_L29e PF01779.17 ORZ00660.1 - 7.2e-24 83.8 13.8 9.7e-24 83.4 13.8 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Sec7 PF01369.20 ORZ00661.1 - 1.2e-66 223.9 0.0 2.1e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 ORZ00661.1 - 1.5e-18 67.2 3.2 1e-17 64.5 1.9 2.8 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORZ00661.1 - 0.043 13.7 1.8 3.1 7.7 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) PPR_2 PF13041.6 ORZ00662.1 - 6.8e-40 135.0 11.5 8.5e-12 45.1 0.1 9.3 6 3 4 10 10 10 8 PPR repeat family PPR PF01535.20 ORZ00662.1 - 1.7e-27 93.7 5.7 5e-07 29.5 0.0 10.1 11 0 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 ORZ00662.1 - 1.4e-26 92.4 1.9 1.4e-05 25.1 0.0 6.8 5 1 3 8 8 8 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORZ00662.1 - 4.2e-20 71.1 11.3 1.2e-06 28.1 0.0 10.0 10 1 0 10 10 10 4 PPR repeat PPR_long PF17177.4 ORZ00662.1 - 3.6e-19 69.0 5.8 1e-06 28.3 0.3 5.3 3 2 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP P16-Arc PF04699.14 ORZ00662.1 - 0.039 14.5 1.9 0.49 10.9 0.0 2.8 2 1 1 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) FlbT PF07378.11 ORZ00662.1 - 0.071 13.2 0.4 0.57 10.3 0.1 2.6 1 1 1 2 2 2 0 Flagellar protein FlbT RPN7 PF10602.9 ORZ00662.1 - 0.62 9.7 6.4 1.9 8.2 0.1 3.3 2 1 0 3 3 3 0 26S proteasome subunit RPN7 ZIP4_domain PF18292.1 ORZ00662.1 - 0.62 10.0 2.7 1.6 8.6 0.1 2.7 3 1 0 3 3 3 0 Zinc transporter ZIP4 domain DRMBL PF07522.14 ORZ00663.1 - 8e-34 116.1 0.0 1.7e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 ORZ00663.1 - 0.00024 20.7 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SET PF00856.28 ORZ00664.1 - 1.1e-18 68.2 0.0 1.1e-18 68.2 0.0 3.7 3 2 0 3 3 3 1 SET domain AWS PF17907.1 ORZ00664.1 - 7.8e-12 45.0 8.3 7.8e-12 45.0 8.3 2.6 3 0 0 3 3 3 1 AWS domain WW PF00397.26 ORZ00664.1 - 8.7e-10 38.5 2.3 2.3e-09 37.2 2.3 1.8 1 0 0 1 1 1 1 WW domain SRI PF08236.11 ORZ00664.1 - 0.00029 21.0 1.8 0.00029 21.0 1.8 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.11 ORZ00664.1 - 0.0011 18.9 0.5 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain SUIM_assoc PF16619.5 ORZ00664.1 - 0.0052 16.8 0.0 0.0052 16.8 0.0 4.1 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Glyco_hyd_101C PF17451.2 ORZ00664.1 - 0.14 12.5 5.2 0.34 11.2 5.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain CAF1C_H4-bd PF12265.8 ORZ00666.1 - 7.1e-28 96.7 0.3 1.4e-26 92.6 0.3 3.0 4 0 0 4 4 4 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORZ00666.1 - 1.2e-23 82.9 14.6 3.9e-06 27.5 0.3 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00666.1 - 2.2e-06 27.9 0.1 0.064 13.6 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain fn3_4 PF16794.5 ORZ00666.1 - 0.032 14.2 0.0 0.97 9.4 0.1 2.5 1 1 1 2 2 2 0 Fibronectin-III type domain FAD_binding_1 PF00667.20 ORZ00667.1 - 5.2e-45 153.7 0.0 7.9e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORZ00667.1 - 1e-35 123.1 0.0 1.8e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORZ00667.1 - 5.4e-12 46.3 0.0 1.8e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Pkinase PF00069.25 ORZ00668.1 - 4.3e-11 42.7 0.2 4.9e-11 42.5 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00668.1 - 2.7e-09 36.7 0.1 3e-09 36.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase HipN PF18253.1 ORZ00668.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain DUF4515 PF14988.6 ORZ00669.1 - 0.0043 16.9 5.1 0.0043 16.9 5.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) APG6_N PF17675.1 ORZ00669.1 - 0.0051 17.3 1.1 0.0051 17.3 1.1 2.3 2 0 0 2 2 2 1 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 ORZ00669.1 - 0.0077 15.8 0.7 0.0077 15.8 0.7 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 SWIRM-assoc_1 PF16495.5 ORZ00669.1 - 0.036 14.0 4.3 0.1 12.6 4.3 1.7 1 0 0 1 1 1 0 SWIRM-associated region 1 DUF1192 PF06698.11 ORZ00669.1 - 0.12 12.5 6.6 1.1 9.4 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) SlyX PF04102.12 ORZ00669.1 - 0.16 12.6 13.8 3.9 8.2 6.2 2.9 2 0 0 2 2 2 0 SlyX ZapB PF06005.12 ORZ00669.1 - 0.79 10.2 7.5 3.5 8.1 7.5 2.1 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 ORZ00669.1 - 0.8 10.4 3.5 1.5 9.5 0.8 2.3 2 0 0 2 2 2 0 Initiation control protein YabA KfrA_N PF11740.8 ORZ00669.1 - 1.6 9.4 17.8 5.1 7.8 8.1 2.8 1 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4407 PF14362.6 ORZ00669.1 - 4.5 6.5 10.6 12 5.1 5.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RRXRR PF14239.6 ORZ00669.1 - 6.3 6.6 10.5 14 5.5 7.7 2.1 1 1 1 2 2 2 0 RRXRR protein DivIC PF04977.15 ORZ00669.1 - 6.6 6.6 9.3 4.1 7.2 5.4 2.3 2 0 0 2 2 2 0 Septum formation initiator FUSC PF04632.12 ORZ00669.1 - 7.6 4.9 14.2 12 4.3 14.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family NAT PF04768.13 ORZ00670.1 - 1.5e-43 148.4 0.0 2.8e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Peptidase_M17 PF00883.21 ORZ00671.1 - 2.5e-61 207.7 0.1 3.2e-61 207.3 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Ank_2 PF12796.7 ORZ00673.1 - 1.9e-19 70.0 0.2 3.4e-09 37.2 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORZ00673.1 - 3.3e-18 65.8 0.3 5.2e-08 33.3 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ00673.1 - 1.7e-17 61.7 1.6 3e-05 24.0 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORZ00673.1 - 1.3e-16 60.4 1.1 1.3e-08 34.9 0.1 3.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORZ00673.1 - 1.6e-15 56.8 3.0 1.1e-05 25.7 0.2 4.4 4 0 0 4 4 4 4 Ankyrin repeat PRIMA1 PF16101.5 ORZ00673.1 - 0.19 11.8 5.9 3.1 7.9 2.1 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 WD40 PF00400.32 ORZ00674.1 - 1.5e-64 212.3 20.7 1.2e-10 41.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00674.1 - 9.7e-25 86.7 3.7 0.00017 21.8 0.0 6.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORZ00674.1 - 3.4e-13 49.1 6.3 0.0019 16.9 0.0 5.5 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 ORZ00674.1 - 5.2e-13 49.3 1.3 1.2e-06 28.6 0.2 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORZ00674.1 - 6.7e-07 28.9 0.1 0.00068 19.1 0.0 3.2 2 1 1 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 ORZ00674.1 - 1.2e-06 27.8 3.8 0.091 11.7 1.2 4.5 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 ORZ00674.1 - 7.8e-06 25.0 6.2 0.29 10.0 0.0 4.5 2 1 3 5 5 5 4 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 ORZ00674.1 - 0.00025 19.5 0.1 0.0013 17.1 0.0 2.0 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 ORZ00674.1 - 0.0023 16.7 7.9 0.75 8.5 0.4 5.1 1 1 5 6 6 6 1 Nup133 N terminal like VID27 PF08553.10 ORZ00674.1 - 0.0072 15.4 0.0 0.14 11.2 0.0 2.5 1 1 2 3 3 3 2 VID27 C-terminal WD40-like domain PD40 PF07676.12 ORZ00674.1 - 0.01 15.8 0.5 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ricin_B_lectin PF00652.22 ORZ00674.1 - 0.032 14.5 0.5 0.14 12.4 0.0 2.3 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain DUF1513 PF07433.11 ORZ00674.1 - 0.12 11.5 0.1 7.3 5.6 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Glycos_transf_2 PF00535.26 ORZ00675.1 - 4.9e-22 78.5 0.0 6.4e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORZ00675.1 - 1.2e-10 41.7 0.0 1.7e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORZ00675.1 - 0.0055 16.2 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Kelch_5 PF13854.6 ORZ00677.1 - 3.9e-30 103.3 5.5 1.2e-07 31.6 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 ORZ00677.1 - 9.6e-26 89.6 9.2 3.1e-07 30.3 0.1 6.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 ORZ00677.1 - 2.5e-24 84.6 5.3 1e-06 28.2 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 ORZ00677.1 - 7.1e-22 77.2 2.8 5.4e-06 26.6 0.0 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 ORZ00677.1 - 4.7e-20 71.1 9.3 6.6e-05 23.0 0.1 6.2 4 2 2 6 6 6 4 Kelch motif Kelch_2 PF07646.15 ORZ00677.1 - 1.3e-14 53.5 7.7 0.00061 19.7 0.0 6.2 6 0 0 6 6 6 4 Kelch motif TFIIS_C PF01096.18 ORZ00678.1 - 1.8e-19 69.3 6.3 1.8e-19 69.3 6.3 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORZ00678.1 - 3.1e-07 30.1 5.1 4e-07 29.8 1.5 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 ORZ00678.1 - 0.00085 19.3 8.8 0.0042 17.0 2.8 2.6 2 1 0 2 2 2 1 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 ORZ00678.1 - 0.0038 16.7 4.0 0.24 10.9 1.7 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding zf-DNA_Pol PF08996.10 ORZ00678.1 - 0.005 16.6 1.2 0.01 15.6 1.2 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger C1_1 PF00130.22 ORZ00678.1 - 0.0066 16.3 0.3 0.0066 16.3 0.3 2.6 2 1 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DpnI PF06044.12 ORZ00678.1 - 0.023 14.4 0.7 0.023 14.4 0.7 2.1 1 1 1 2 2 2 0 Dam-replacing family zinc-ribbons_6 PF07191.12 ORZ00678.1 - 0.043 13.8 1.2 0.043 13.8 1.2 2.4 2 1 0 2 2 2 0 zinc-ribbons PH_17 PF18012.1 ORZ00678.1 - 0.047 13.4 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 PH domain Baculo_LEF5_C PF11792.8 ORZ00678.1 - 0.049 13.3 3.0 0.1 12.3 3.0 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Auto_anti-p27 PF06677.12 ORZ00678.1 - 0.069 13.3 4.5 0.19 11.9 0.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PH_10 PF15411.6 ORZ00678.1 - 0.1 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain zf-ribbon_3 PF13248.6 ORZ00678.1 - 0.11 11.9 6.1 0.97 8.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_KTR PF14205.6 ORZ00678.1 - 0.21 11.4 4.3 7.5 6.4 0.1 2.9 2 1 1 3 3 3 0 Cysteine-rich KTR Rubredoxin PF00301.20 ORZ00678.1 - 0.21 11.6 6.1 6.2 6.9 0.1 3.2 3 0 0 3 3 3 0 Rubredoxin HscB_4_cys PF18256.1 ORZ00678.1 - 0.43 10.4 7.6 13 5.7 0.5 3.4 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-C3HC4_4 PF15227.6 ORZ00678.1 - 1.9 8.7 11.8 2.9 8.1 1.8 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Ribosomal_S27e PF01667.17 ORZ00678.1 - 6.1 6.6 9.3 2.1 8.1 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein S27 2OG-FeII_Oxy_2 PF13532.6 ORZ00679.1 - 1.4e-33 116.8 0.0 4.6e-32 111.8 0.0 2.3 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily GHMP_kinases_N PF00288.26 ORZ00680.1 - 8e-08 32.4 0.0 3.9e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain NTP_transf_3 PF12804.7 ORZ00680.1 - 4.9e-06 27.0 0.1 2.4e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain GHMP_kinases_C PF08544.13 ORZ00680.1 - 0.0091 16.3 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GTP_EFTU PF00009.27 ORZ00681.1 - 1.8e-55 187.5 0.0 2.8e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORZ00681.1 - 4.3e-42 142.9 0.0 9e-42 141.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORZ00681.1 - 1.3e-14 54.3 1.5 1.3e-14 54.3 1.5 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORZ00681.1 - 0.00054 20.0 0.2 0.012 15.7 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2011 PF09428.10 ORZ00682.1 - 0.0012 19.0 0.2 0.0036 17.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) DUF4710 PF15828.5 ORZ00682.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) DUF3801 PF12687.7 ORZ00682.1 - 0.42 10.7 8.7 0.81 9.7 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) P34-Arc PF04045.14 ORZ00684.1 - 1.2e-104 349.3 1.1 1.5e-104 348.9 1.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF3770 PF12603.8 ORZ00684.1 - 0.08 12.4 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) SNF2_N PF00176.23 ORZ00685.1 - 1.1e-71 241.5 1.6 1.1e-71 241.5 1.6 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 ORZ00685.1 - 1.6e-20 72.9 2.2 3.3e-20 71.9 0.5 2.4 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 ORZ00685.1 - 3.5e-20 72.4 0.1 1.1e-18 67.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 ORZ00685.1 - 1.8e-14 53.8 10.1 1.8e-14 53.8 10.1 3.2 3 0 0 3 3 3 1 HSA SnAC PF14619.6 ORZ00685.1 - 1.1e-13 51.5 7.4 1.1e-13 51.5 7.4 4.1 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 ORZ00685.1 - 1.1e-08 35.2 1.5 4.5e-08 33.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORZ00685.1 - 0.00056 19.7 2.1 0.001 18.9 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Gti1_Pac2 PF09729.9 ORZ00685.1 - 0.51 10.4 16.8 2.6 8.1 3.9 3.7 3 0 0 3 3 3 0 Gti1/Pac2 family CFIA_Pcf11 PF11526.8 ORZ00685.1 - 1.4 9.5 7.3 1 9.9 0.4 3.0 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 P4Ha_N PF08336.11 ORZ00686.1 - 0.059 13.4 0.0 0.069 13.2 0.0 1.0 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region GrpE PF01025.19 ORZ00686.1 - 0.085 12.5 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 GrpE YtxH PF12732.7 ORZ00686.1 - 3.7 8.1 4.7 2.2 8.9 0.2 2.0 2 0 0 2 2 2 0 YtxH-like protein DUF883 PF05957.13 ORZ00686.1 - 8.3 7.1 8.1 49 4.6 8.1 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.7 ORZ00687.1 - 4e-07 29.8 2.9 4e-07 29.8 2.9 3.0 3 0 0 3 3 3 1 F-box-like STE PF02200.16 ORZ00688.1 - 1.8e-53 179.6 0.1 2.7e-53 179.1 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor RskA PF10099.9 ORZ00688.1 - 0.046 14.0 1.5 0.091 13.1 1.5 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA NAD_binding_2 PF03446.15 ORZ00689.1 - 3.9e-27 95.4 0.2 5.8e-27 94.8 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORZ00689.1 - 2e-06 28.0 0.0 4.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORZ00689.1 - 6.1e-05 23.5 0.3 0.00015 22.3 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORZ00689.1 - 7e-05 22.9 0.2 0.00014 22.0 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ORZ00689.1 - 9.6e-05 21.8 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 ORZ00689.1 - 0.00013 22.6 1.7 0.00016 22.3 0.9 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain IlvN PF07991.12 ORZ00689.1 - 0.0012 18.5 0.2 0.0018 17.8 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 ORZ00689.1 - 0.0047 16.8 1.2 0.0062 16.4 0.2 1.7 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 ORZ00689.1 - 0.01 15.7 1.3 0.028 14.3 1.3 1.9 1 1 0 1 1 1 1 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 ORZ00689.1 - 0.024 14.6 0.3 0.071 13.1 0.3 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ORZ00689.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RRM_1 PF00076.22 ORZ00690.1 - 2.3e-38 129.8 0.0 2e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ00690.1 - 3.5e-05 23.8 0.0 0.00021 21.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 ORZ00690.1 - 0.0032 17.1 0.2 0.31 10.7 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain RRM_5 PF13893.6 ORZ00690.1 - 0.014 15.0 0.0 0.76 9.4 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORZ00690.1 - 0.11 12.5 0.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Nkap_C PF06047.11 ORZ00691.1 - 1.7e-47 159.7 4.5 1.7e-47 159.7 4.5 2.1 2 1 1 3 3 3 1 NF-kappa-B-activating protein C-terminal domain GAGA_bind PF06217.12 ORZ00691.1 - 0.28 11.4 13.2 0.24 11.6 8.9 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Zip PF02535.22 ORZ00691.1 - 1.2 8.3 6.4 2.1 7.5 6.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 ORZ00691.1 - 2.5 6.8 10.0 3.5 6.3 10.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 ORZ00691.1 - 3.3 6.4 15.6 0.15 10.8 10.0 1.6 2 0 0 2 2 2 0 Presenilin MutL_C PF08676.11 ORZ00692.1 - 1.1e-26 93.4 0.2 2.3e-26 92.3 0.2 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ORZ00692.1 - 4.7e-24 84.3 0.0 1.5e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORZ00692.1 - 9.6e-14 51.4 0.0 2.4e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORZ00692.1 - 2.4e-05 24.8 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ccdc124 PF06244.12 ORZ00693.1 - 3.1e-27 95.6 28.5 3.1e-27 95.6 28.5 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Dsh_C PF12316.8 ORZ00693.1 - 3 8.2 6.6 5.3 7.4 6.6 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Glyco_transf_49 PF13896.6 ORZ00694.1 - 7.2e-60 203.1 4.7 1.6e-47 162.5 1.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan YqzE PF14038.6 ORZ00695.1 - 0.06 13.4 1.8 0.097 12.7 1.8 1.3 1 0 0 1 1 1 0 YqzE-like protein Radical_SAM PF04055.21 ORZ00696.1 - 2.6e-13 50.7 0.0 8.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 ORZ00696.1 - 0.00066 19.8 0.1 0.0022 18.1 0.1 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Phage_tail_APC PF16778.5 ORZ00696.1 - 0.012 15.5 0.0 0.32 10.9 0.0 2.9 3 0 0 3 3 3 0 Phage tail assembly chaperone protein zf-C2H2 PF00096.26 ORZ00697.1 - 1.4e-13 50.4 11.1 2.1e-07 31.0 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ00697.1 - 1.1e-07 31.9 16.4 2.3e-06 27.8 4.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ00697.1 - 1.9e-07 31.4 9.3 0.0025 18.5 1.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORZ00697.1 - 0.0047 17.1 4.6 0.045 13.9 0.8 1.9 1 1 0 1 1 1 1 Aberrant zinc-finger OrsD PF12013.8 ORZ00697.1 - 0.017 15.6 1.5 0.12 12.8 0.2 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 ORZ00697.1 - 0.02 15.2 6.3 0.32 11.3 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 ORZ00697.1 - 0.092 12.7 0.2 0.092 12.7 0.2 2.6 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 ORZ00697.1 - 0.097 13.3 2.5 0.63 10.7 0.2 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF5583 PF17821.1 ORZ00697.1 - 0.2 11.6 4.6 0.096 12.6 1.6 1.8 1 1 0 2 2 2 0 Family of unknown function (DUF5583) zf-met PF12874.7 ORZ00697.1 - 0.22 12.0 10.0 1.1 9.7 3.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORZ00697.1 - 0.25 11.7 4.3 0.45 10.9 0.9 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORZ00697.1 - 0.4 10.7 9.4 1.3 9.1 1.5 2.6 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 ORZ00697.1 - 1.5 8.6 15.6 6.2 6.7 2.5 3.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORZ00697.1 - 2.6 8.1 10.1 0.3 11.2 1.7 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Macoilin PF09726.9 ORZ00697.1 - 3.9 5.9 7.6 4.5 5.7 7.6 1.0 1 0 0 1 1 1 0 Macoilin family IPP-2 PF04979.14 ORZ00699.1 - 1.4e-16 61.4 17.9 3.2e-12 47.3 8.9 2.1 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) SARAF PF06682.12 ORZ00699.1 - 0.12 12.0 0.2 0.26 10.9 0.0 1.6 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Macoilin PF09726.9 ORZ00701.1 - 0.12 10.9 20.1 0.2 10.2 20.1 1.3 1 1 0 1 1 1 0 Macoilin family DUF2040 PF09745.9 ORZ00703.1 - 3.3e-32 111.1 29.6 3.3e-32 111.1 29.6 4.2 3 2 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) cNMP_binding PF00027.29 ORZ00704.1 - 7.7e-22 77.2 0.1 7.6e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain IBN_N PF03810.19 ORZ00705.1 - 6.1e-15 54.9 0.0 6.4e-14 51.6 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ORZ00705.1 - 6.9e-05 22.9 0.2 0.0018 18.3 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 ORZ00705.1 - 8.6e-05 22.9 2.1 0.021 15.2 0.0 4.2 3 1 1 4 4 4 1 HEAT repeats SDA1 PF05285.12 ORZ00706.1 - 0.15 11.5 17.7 0.084 12.3 8.2 2.5 2 0 0 2 2 2 0 SDA1 Sigma70_ner PF04546.13 ORZ00706.1 - 0.21 11.4 11.8 2 8.3 8.2 3.0 3 1 0 3 3 3 0 Sigma-70, non-essential region Pes-10 PF07149.11 ORZ00706.1 - 2.5 7.1 15.6 0.22 10.5 10.7 1.7 2 0 0 2 2 2 0 Pes-10 RRN3 PF05327.11 ORZ00706.1 - 6.1 5.3 13.4 1.4 7.4 7.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DDDD PF10161.9 ORZ00707.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.9 2 0 0 2 2 2 0 Putative mitochondrial precursor protein EamA PF00892.20 ORZ00709.1 - 3e-11 43.7 22.0 8.3e-07 29.3 1.3 2.6 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 ORZ00709.1 - 8.5e-09 35.0 12.3 1.6e-08 34.1 12.3 1.4 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 ORZ00709.1 - 1.2e-08 34.5 1.9 1.2e-08 34.5 1.9 1.6 1 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 ORZ00709.1 - 7.9e-06 25.4 13.8 3e-05 23.5 11.2 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 ORZ00709.1 - 2.7e-05 23.3 15.1 0.00026 20.0 2.8 3.2 3 0 0 3 3 3 3 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 ORZ00709.1 - 0.037 13.2 12.2 0.3 10.3 9.8 2.7 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport SLC35F PF06027.12 ORZ00709.1 - 0.084 12.4 12.9 0.28 10.7 12.9 1.8 1 1 0 1 1 1 0 Solute carrier family 35 DUF202 PF02656.15 ORZ00710.1 - 2.5e-23 82.3 1.5 2.5e-23 82.3 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MscS_TM PF12794.7 ORZ00710.1 - 0.0096 14.8 1.5 0.014 14.3 1.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 YtpI PF14007.6 ORZ00710.1 - 0.013 15.7 5.1 0.081 13.1 5.5 2.1 3 0 0 3 3 3 0 YtpI-like protein Peptidase_C48 PF02902.19 ORZ00711.1 - 3e-43 148.2 0.0 3.7e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 ORZ00711.1 - 0.012 14.3 0.1 0.17 10.6 0.0 2.1 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase FlaE PF07559.14 ORZ00711.1 - 0.18 12.3 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar basal body protein FlaE Calpain_inhib PF00748.19 ORZ00712.1 - 0.009 16.5 0.5 0.01 16.3 0.5 1.2 1 0 0 1 1 1 1 Calpain inhibitor EBP50_C PF09007.11 ORZ00712.1 - 0.0097 16.9 0.8 0.013 16.5 0.8 1.3 1 0 0 1 1 1 1 EBP50, C-terminal MAGI_u5 PF16666.5 ORZ00712.1 - 1.6 8.9 9.5 11 6.1 0.0 2.5 1 1 1 2 2 2 0 Unstructured region on MAGI p450 PF00067.22 ORZ00713.1 - 5e-83 279.4 0.0 5.7e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Telomere_reg-2 PF10193.9 ORZ00713.1 - 0.057 13.9 0.1 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Telomere length regulation protein Oxidored_FMN PF00724.20 ORZ00714.1 - 6e-98 328.2 0.0 7.1e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.32 ORZ00715.1 - 1.6e-20 73.0 21.5 0.0001 23.0 0.2 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00715.1 - 3.3e-08 33.7 7.3 0.02 15.2 0.2 4.0 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain VCBS PF13517.6 ORZ00715.1 - 0.011 16.3 1.8 54 4.5 0.1 4.6 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TFIIIC_delta PF12657.7 ORZ00715.1 - 0.014 15.3 0.6 0.014 15.3 0.6 3.1 1 1 2 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 ORZ00715.1 - 0.019 13.0 1.3 0.33 8.9 0.1 2.1 2 0 0 2 2 2 0 IKI3 family XG_FTase PF03254.13 ORZ00716.1 - 2.8e-08 32.9 0.4 2.1e-05 23.3 0.1 2.8 2 1 0 3 3 3 2 Xyloglucan fucosyltransferase NodZ PF05830.11 ORZ00716.1 - 0.00049 19.0 0.4 0.0018 17.2 0.0 1.9 2 1 0 2 2 2 1 Nodulation protein Z (NodZ) TPR_1 PF00515.28 ORZ00717.1 - 8.7e-39 129.8 27.7 2.6e-05 23.8 0.0 11.0 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ00717.1 - 3e-35 117.5 28.8 0.0017 18.3 0.1 11.9 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ00717.1 - 8.1e-26 89.4 22.1 5.1e-07 29.3 0.6 8.7 6 2 3 9 9 9 6 TPR repeat TPR_17 PF13431.6 ORZ00717.1 - 1.7e-25 87.5 11.7 0.012 16.0 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00717.1 - 6.4e-25 87.5 22.0 2e-06 28.3 0.4 7.4 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ00717.1 - 7.4e-20 69.5 23.0 0.0017 18.4 0.2 10.9 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ00717.1 - 1.2e-18 67.4 24.5 1.7e-06 28.4 2.9 7.8 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ00717.1 - 7.9e-18 63.6 24.4 0.0064 17.2 0.2 10.1 4 2 8 12 12 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ00717.1 - 3.8e-15 55.9 30.0 9.9e-06 25.8 1.3 8.7 2 2 7 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ00717.1 - 1.3e-12 46.8 18.5 0.00042 20.1 0.1 8.6 9 1 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ00717.1 - 7.1e-10 38.9 13.6 0.0097 16.0 0.0 6.7 5 3 2 7 7 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ORZ00717.1 - 1.2e-07 31.4 9.1 0.027 13.8 2.2 4.0 3 1 1 4 4 4 3 MalT-like TPR region ANAPC3 PF12895.7 ORZ00717.1 - 1.7e-07 31.3 11.8 0.2 11.9 0.1 5.5 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 ORZ00717.1 - 7.3e-06 26.2 5.7 0.58 10.5 0.1 5.2 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORZ00717.1 - 1.1e-05 24.9 5.2 0.0073 15.6 0.5 4.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ00717.1 - 1.2e-05 25.7 33.7 0.0016 18.9 0.0 9.7 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORZ00717.1 - 1.2e-05 25.0 21.5 0.14 12.0 0.1 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_4 PF07721.14 ORZ00717.1 - 0.00016 22.0 5.4 5.5 7.9 0.0 6.7 8 0 0 8 8 5 2 Tetratricopeptide repeat DUF4810 PF16068.5 ORZ00717.1 - 0.00023 21.7 1.0 1.3 9.6 0.0 4.8 5 1 0 5 5 5 1 Domain of unknown function (DUF4810) DUF3856 PF12968.7 ORZ00717.1 - 0.0018 18.4 2.5 6.3 6.9 0.0 5.0 3 1 2 5 5 5 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 ORZ00717.1 - 0.0023 16.9 2.3 4 6.2 0.0 3.8 2 1 0 4 4 4 1 NMDA receptor-regulated protein 1 SPO22 PF08631.10 ORZ00717.1 - 0.007 15.9 5.3 0.0092 15.5 0.0 3.3 4 2 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_21 PF09976.9 ORZ00717.1 - 0.016 14.9 11.5 0.78 9.4 0.1 4.5 2 1 1 4 4 4 0 Tetratricopeptide repeat-like domain ANAPC5 PF12862.7 ORZ00717.1 - 0.05 13.7 8.2 15 5.7 0.1 4.6 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 5 TAF1_subA PF14929.6 ORZ00717.1 - 0.46 9.8 2.3 0.5 9.7 0.4 1.9 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A Vps55 PF04133.14 ORZ00718.1 - 8.8e-45 151.4 7.4 9.9e-45 151.3 7.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 PIRT PF15099.6 ORZ00718.1 - 0.22 11.1 0.3 0.22 11.1 0.3 1.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family LRR_6 PF13516.6 ORZ00719.1 - 1.5e-05 24.7 0.1 39 4.6 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.7 ORZ00719.1 - 4.2e-05 23.3 0.1 0.00012 21.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORZ00719.1 - 0.00038 20.8 0.2 0.055 13.9 0.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORZ00719.1 - 0.0018 18.5 1.6 4.4 8.2 0.1 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 ORZ00719.1 - 0.1 12.4 0.2 9.4 6.1 0.0 3.1 3 1 1 4 4 4 0 Leucine rich repeat Deltaretro_Tax PF05599.11 ORZ00719.1 - 0.12 12.9 0.3 0.2 12.2 0.3 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Transp_inhibit PF18791.1 ORZ00719.1 - 0.16 11.5 0.1 9 5.9 0.0 3.0 3 0 0 3 3 3 0 Transport inhibitor response 1 protein domain Peptidase_S9 PF00326.21 ORZ00720.1 - 1.2e-43 149.1 0.0 1.8e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORZ00720.1 - 5.2e-09 36.0 0.0 1.1e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORZ00720.1 - 2e-06 27.8 0.0 8.8e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORZ00720.1 - 2.5e-05 23.7 0.0 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORZ00720.1 - 6.9e-05 22.6 0.2 0.12 12.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 ORZ00720.1 - 0.0012 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 ORZ00720.1 - 0.002 16.9 0.1 0.024 13.3 0.0 2.3 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ORZ00720.1 - 0.0061 16.5 0.0 0.2 11.5 0.0 2.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 ORZ00720.1 - 0.027 14.1 0.0 2.8 7.4 0.0 2.3 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Arm-DNA-bind_5 PF17293.2 ORZ00720.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain WD40 PF00400.32 ORZ00721.1 - 1.8e-12 47.5 3.8 0.5 11.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00721.1 - 0.00043 20.5 0.1 14 6.0 0.0 4.5 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TrkH PF02386.16 ORZ00722.1 - 1.3e-72 244.9 1.2 6.6e-72 242.6 1.2 1.8 1 1 0 1 1 1 1 Cation transport protein CTP_synth_N PF06418.14 ORZ00723.1 - 1.7e-125 417.7 0.1 2.2e-125 417.3 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ORZ00723.1 - 2.9e-54 183.7 0.0 4.9e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORZ00723.1 - 0.00063 19.6 0.1 0.0085 15.9 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 ORZ00723.1 - 0.011 15.7 0.0 0.041 13.9 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PH_9 PF15410.6 ORZ00724.1 - 6.6e-31 107.1 0.5 3.4e-30 104.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 ORZ00724.1 - 7.9e-31 107.2 0.2 7.9e-31 107.2 0.2 1.6 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 ORZ00724.1 - 0.00013 22.4 0.0 0.0044 17.5 0.0 2.7 1 1 0 1 1 1 1 PH domain HLH PF00010.26 ORZ00727.1 - 3.2e-17 62.2 0.6 3.2e-17 62.2 0.6 2.4 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Pox_A_type_inc PF04508.12 ORZ00727.1 - 0.0054 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat DUF4407 PF14362.6 ORZ00727.1 - 0.078 12.3 1.6 0.11 11.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 ORZ00728.1 - 1.8e-55 187.5 0.0 2.8e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORZ00728.1 - 4.3e-42 142.9 0.0 9e-42 141.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORZ00728.1 - 1.3e-14 54.3 1.5 1.3e-14 54.3 1.5 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORZ00728.1 - 0.00054 20.0 0.2 0.012 15.7 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PLDc_2 PF13091.6 ORZ00729.1 - 9.7e-28 96.7 0.2 2e-27 95.6 0.2 1.6 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 ORZ00729.1 - 2.2e-05 24.2 1.4 0.0028 17.2 1.4 2.4 1 1 0 1 1 1 1 FAM83 A-H PLDc PF00614.22 ORZ00729.1 - 0.012 15.8 0.1 0.028 14.6 0.1 1.7 1 0 0 1 1 1 0 Phospholipase D Active site motif U79_P34 PF03064.16 ORZ00729.1 - 0.049 13.0 0.9 0.075 12.4 0.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM199X PF15814.5 ORZ00730.1 - 0.042 12.9 0.2 0.085 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein family FAM199X UPF0139 PF03669.13 ORZ00731.1 - 3.8e-12 45.9 0.0 4.9e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Hpt PF01627.23 ORZ00732.1 - 3.1e-12 46.6 0.0 4.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Hpt domain RACo_C_ter PF14574.6 ORZ00732.1 - 0.043 12.9 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain MFS_1 PF07690.16 ORZ00733.1 - 2e-32 112.5 52.1 1.8e-27 96.2 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily G-patch PF01585.23 ORZ00734.1 - 2.7e-13 49.6 0.8 2.7e-13 49.6 0.8 2.0 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 ORZ00734.1 - 2.9e-11 43.2 0.0 7.2e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 ORZ00734.1 - 7.8e-07 29.1 0.2 7.8e-07 29.1 0.2 3.6 3 0 0 3 3 3 1 G-patch domain DUF1493 PF07377.12 ORZ00734.1 - 0.012 16.0 1.0 0.04 14.4 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) GPI-anchored PF10342.9 ORZ00735.1 - 2.7e-15 56.9 0.5 6.2e-15 55.7 0.5 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIID-31kDa PF02291.15 ORZ00736.1 - 4.7e-50 168.7 0.0 6.3e-50 168.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORZ00736.1 - 3.2e-07 30.3 0.0 5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 ORZ00736.1 - 8e-05 23.0 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORZ00736.1 - 0.0052 17.1 0.1 0.0079 16.6 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein TAF PF02969.17 ORZ00736.1 - 0.0087 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID_30kDa PF03540.13 ORZ00736.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit TFIID_20kDa PF03847.13 ORZ00736.1 - 0.013 15.9 0.2 0.042 14.3 0.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.16 ORZ00737.1 - 2.4e-125 418.1 11.5 3e-125 417.8 11.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Tetraspanin PF00335.20 ORZ00739.1 - 2.9e-10 40.3 0.2 5.7e-09 36.0 1.3 1.9 1 1 1 2 2 2 2 Tetraspanin family WD40 PF00400.32 ORZ00740.1 - 3.6e-48 160.5 21.0 4.3e-07 30.5 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00740.1 - 2.1e-11 43.9 1.6 0.051 13.9 0.1 5.7 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORZ00740.1 - 1.3e-08 34.0 7.2 0.15 10.7 0.0 6.0 4 2 2 7 7 7 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 ORZ00740.1 - 0.00038 20.5 0.2 28 4.8 0.0 4.9 3 1 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 ORZ00740.1 - 0.002 17.5 0.0 0.71 9.1 0.0 3.3 3 1 0 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 ORZ00740.1 - 0.0062 15.3 3.4 3.4 6.3 0.1 3.8 2 2 1 4 4 4 2 Nup133 N terminal like PQQ_3 PF13570.6 ORZ00740.1 - 0.034 14.7 0.1 34 5.1 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain DUF5046 PF16465.5 ORZ00740.1 - 0.041 13.3 0.0 4.1 6.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) CNH PF00780.22 ORZ00740.1 - 0.13 11.8 0.0 5.8 6.4 0.0 3.0 2 1 1 3 3 3 0 CNH domain PQQ PF01011.21 ORZ00740.1 - 0.2 11.6 0.5 30 4.8 0.0 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat RWD PF05773.22 ORZ00741.1 - 4.8e-20 72.0 0.2 1.1e-19 70.8 0.2 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 ORZ00741.1 - 2.9e-07 30.9 10.6 3.4e-07 30.7 8.7 2.1 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Metallophos PF00149.28 ORZ00742.1 - 2.8e-10 41.0 0.1 5.4e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NolX PF05819.11 ORZ00742.1 - 0.044 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 NolX protein Ribosomal_L22e PF01776.17 ORZ00743.1 - 1.6e-46 157.2 1.1 1.9e-46 157.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF4845 PF16137.5 ORZ00743.1 - 0.036 14.9 0.1 0.055 14.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4845) RCR PF12273.8 ORZ00744.1 - 0.0055 17.3 0.2 0.031 14.9 0.2 2.2 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Protocadherin PF08374.11 ORZ00744.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DUF2142 PF09913.9 ORZ00744.1 - 0.028 13.3 0.2 0.041 12.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF1772 PF08592.11 ORZ00744.1 - 0.037 14.3 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF570 PF04489.13 ORZ00744.1 - 0.068 11.8 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) CCSMST1 PF15013.6 ORZ00744.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 CCSMST1 family DUF515 PF04415.12 ORZ00744.1 - 0.1 10.9 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF805 PF05656.14 ORZ00744.1 - 0.11 12.9 1.7 0.18 12.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) LPG_synthase_TM PF03706.13 ORZ00744.1 - 0.49 9.9 5.5 6.7 6.2 5.7 2.0 1 1 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region TMEM154 PF15102.6 ORZ00745.1 - 0.057 13.3 0.1 0.057 13.3 0.1 3.1 3 0 0 3 3 3 0 TMEM154 protein family Syndecan PF01034.20 ORZ00745.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 ORZ00745.1 - 0.15 12.9 0.0 0.15 12.9 0.0 2.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 ORZ00745.1 - 2.4 7.9 8.1 0.11 12.3 0.4 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2615 PF11027.8 ORZ00745.1 - 3.6 7.8 8.3 1.2 9.3 0.1 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2615) Abhydrolase_6 PF12697.7 ORZ00746.1 - 1.5e-09 38.8 0.0 2e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORZ00746.1 - 3.1e-05 23.4 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cytochrom_C1 PF02167.15 ORZ00748.1 - 7.3e-98 326.6 0.0 1.2e-97 326.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ORZ00748.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ORZ00748.1 - 0.036 15.2 0.2 0.12 13.5 0.2 2.0 1 1 0 1 1 1 0 Cytochrome c Fe_hyd_lg_C PF02906.14 ORZ00749.1 - 5.1e-76 255.5 0.0 5e-74 249.0 0.0 2.1 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 ORZ00749.1 - 3.9e-08 33.2 0.0 8.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit LAGLIDADG_3 PF14528.6 ORZ00751.1 - 0.0057 17.0 0.9 3.8 7.9 0.0 2.6 2 0 0 2 2 2 2 LAGLIDADG-like domain LRR_4 PF12799.7 ORZ00752.1 - 0.00083 19.7 5.9 4.2 7.9 0.1 5.6 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) MG1 PF17790.1 ORZ00753.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.6 2 0 0 2 2 2 0 Macroglobulin domain MG1 Chromo PF00385.24 ORZ00754.1 - 9.7e-06 25.4 0.5 1.3e-05 25.0 0.5 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 ORZ00754.1 - 0.00054 19.8 0.5 0.00054 19.8 0.5 1.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Mcp5_PH PF12814.7 ORZ00755.1 - 3.5e-37 127.2 0.0 7.3e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 ORZ00755.1 - 0.0035 17.8 0.0 0.0084 16.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Fibin PF15819.5 ORZ00755.1 - 0.24 11.1 10.2 0.67 9.7 10.2 1.8 1 0 0 1 1 1 0 Fin bud initiation factor homologue WSD PF15613.6 ORZ00755.1 - 0.5 10.9 4.4 23 5.5 0.0 3.4 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Filament PF00038.21 ORZ00755.1 - 1.6 8.2 40.4 0.23 11.0 24.8 3.5 3 0 0 3 3 3 0 Intermediate filament protein bZIP_1 PF00170.21 ORZ00757.1 - 1.1e-08 35.0 25.2 1.2e-08 34.9 22.2 2.5 2 1 0 2 2 2 1 bZIP transcription factor Rootletin PF15035.6 ORZ00757.1 - 0.00017 21.6 10.7 0.00017 21.6 10.7 3.2 3 0 0 3 3 3 2 Ciliary rootlet component, centrosome cohesion bZIP_2 PF07716.15 ORZ00757.1 - 0.0016 18.5 12.8 0.0016 18.5 12.8 3.5 3 1 1 4 4 4 1 Basic region leucine zipper PAP1 PF08601.10 ORZ00757.1 - 0.0074 16.1 0.7 0.0074 16.1 0.7 3.9 2 1 1 3 3 3 1 Transcription factor PAP1 DUF4407 PF14362.6 ORZ00757.1 - 0.34 10.2 11.9 0.59 9.4 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PepSY_TM PF03929.16 ORZ00757.1 - 2.7 7.6 4.9 0.6 9.7 1.3 1.7 2 0 0 2 2 2 0 PepSY-associated TM region SR-25 PF10500.9 ORZ00757.1 - 4.7 6.7 32.2 0.58 9.7 8.6 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Kdo PF06293.14 ORZ00758.1 - 1.3e-10 41.0 0.1 1.9e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORZ00758.1 - 1.2e-08 34.8 0.1 4e-08 33.1 0.0 1.6 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 ORZ00758.1 - 2.7e-08 34.1 0.0 4.1e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 ORZ00758.1 - 6.6e-08 32.2 0.1 8.4e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 ORZ00758.1 - 0.00065 19.3 0.0 0.0037 16.9 0.0 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 ORZ00758.1 - 0.0013 18.1 0.2 0.0018 17.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 ORZ00758.1 - 0.0059 16.3 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.20 ORZ00758.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase PI3_PI4_kinase PF00454.27 ORZ00758.1 - 0.14 11.9 0.1 0.5 10.1 0.0 1.9 2 1 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase KH_8 PF17903.1 ORZ00759.1 - 6.6e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ORZ00759.1 - 0.0014 18.4 0.4 0.0029 17.4 0.4 1.5 1 0 0 1 1 1 1 KH domain MAD PF05557.13 ORZ00760.1 - 4.4e-23 81.5 33.0 7.8e-23 80.7 33.0 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein YabA PF06156.13 ORZ00760.1 - 0.009 16.6 6.8 0.009 16.6 6.8 4.8 2 2 2 4 4 4 1 Initiation control protein YabA CENP-H PF05837.12 ORZ00760.1 - 0.018 15.4 7.9 0.018 15.4 7.9 4.5 3 2 1 4 4 4 0 Centromere protein H (CENP-H) Spc7 PF08317.11 ORZ00761.1 - 0.00023 20.2 2.8 0.00026 20.0 2.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 ORZ00761.1 - 0.0017 18.6 3.9 0.0028 17.9 3.9 1.3 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Rab5-bind PF09311.11 ORZ00761.1 - 0.0053 16.2 4.6 0.0061 16.0 4.6 1.0 1 0 0 1 1 1 1 Rabaptin-like protein Filament PF00038.21 ORZ00761.1 - 0.013 15.1 5.1 0.016 14.8 5.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF3829 PF12889.7 ORZ00761.1 - 0.014 14.9 3.2 0.018 14.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Mago_nashi PF02792.14 ORZ00761.1 - 0.038 14.1 0.6 0.046 13.8 0.6 1.2 1 0 0 1 1 1 0 Mago nashi protein CCDC53 PF10152.9 ORZ00761.1 - 0.2 12.1 3.0 0.26 11.7 3.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4407 PF14362.6 ORZ00761.1 - 0.2 11.0 3.8 0.25 10.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C58 PF03543.14 ORZ00761.1 - 0.21 11.3 2.8 0.26 10.9 2.8 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Seryl_tRNA_N PF02403.22 ORZ00761.1 - 1.8 8.8 9.3 4.5 7.5 9.3 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1688 PF07958.11 ORZ00762.1 - 1.7e-138 461.9 0.0 1.9e-138 461.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) ERO1 PF04137.15 ORZ00763.1 - 1.4e-126 422.4 1.0 1.7e-126 422.2 1.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) NMT_C PF02799.15 ORZ00764.1 - 9.2e-80 267.1 0.0 1.6e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 ORZ00764.1 - 1.7e-74 249.0 0.1 3.1e-73 244.9 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 ORZ00764.1 - 7.7e-05 22.9 0.0 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORZ00764.1 - 0.0043 17.1 0.0 0.72 9.9 0.0 2.8 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORZ00764.1 - 0.036 14.5 0.0 0.67 10.4 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GET2 PF08690.10 ORZ00764.1 - 0.86 9.2 5.2 1.5 8.5 5.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 HORMA PF02301.18 ORZ00764.1 - 1.2 8.7 4.0 2.7 7.5 3.4 1.8 2 0 0 2 2 2 0 HORMA domain RAMP4 PF06624.12 ORZ00765.1 - 0.041 13.9 0.3 0.054 13.6 0.3 1.2 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 C2 PF00168.30 ORZ00766.1 - 4.7e-21 75.0 2.6 2.9e-10 40.3 0.6 2.4 2 0 0 2 2 2 2 C2 domain MMM1 PF10296.9 ORZ00766.1 - 0.09 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Amidohydro_1 PF01979.20 ORZ00767.1 - 3.9e-20 72.5 0.3 6.5e-20 71.7 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORZ00767.1 - 1.1e-11 44.9 0.2 1.6e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Glyco_tranf_2_5 PF13712.6 ORZ00767.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family HIG_1_N PF04588.13 ORZ00768.1 - 2.1e-07 31.0 1.0 2.1e-07 31.0 1.0 3.3 3 1 0 3 3 3 1 Hypoxia induced protein conserved region MurJ PF03023.14 ORZ00768.1 - 0.0084 14.8 0.2 0.013 14.1 0.2 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ SARAF PF06682.12 ORZ00768.1 - 0.073 12.7 3.7 4.9 6.7 0.6 2.7 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Romo1 PF10247.9 ORZ00768.1 - 0.16 12.4 0.6 0.16 12.4 0.6 1.8 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Bacteriocin_IIc PF10439.9 ORZ00768.1 - 0.65 10.2 6.8 6.8 6.9 1.1 3.1 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 ORZ00768.1 - 2 8.2 11.9 25 4.7 11.7 2.3 1 1 0 1 1 1 0 YMGG-like Gly-zipper STE PF02200.16 ORZ00769.1 - 2.5e-53 179.1 0.0 3.9e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 ORZ00769.1 - 1.4e-10 41.0 11.4 7.4e-05 23.0 1.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ00769.1 - 2.8e-08 33.8 15.1 8.8e-08 32.2 2.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ00769.1 - 3.4e-07 30.6 12.9 0.00067 20.3 0.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORZ00769.1 - 0.00011 22.0 1.3 0.00011 22.0 1.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORZ00769.1 - 0.05 13.9 2.5 0.77 10.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORZ00769.1 - 0.27 11.7 3.7 1.4 9.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Fasciclin PF02469.22 ORZ00770.1 - 1.5e-13 51.1 0.6 2e-13 50.7 0.6 1.1 1 0 0 1 1 1 1 Fasciclin domain WD40 PF00400.32 ORZ00771.1 - 8e-36 121.5 2.0 1.6e-06 28.8 0.0 7.3 6 1 1 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.11 ORZ00771.1 - 1.9e-34 117.4 1.9 3.4e-34 116.6 1.9 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 ORZ00771.1 - 2e-18 66.5 0.0 0.0041 17.4 0.0 5.7 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ00771.1 - 0.00055 19.4 0.0 0.091 12.1 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 ORZ00771.1 - 0.0013 17.7 0.0 0.11 11.4 0.0 2.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORZ00771.1 - 0.0014 17.3 1.7 3.8 6.0 0.1 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 U-box PF04564.15 ORZ00771.1 - 0.0029 17.7 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF3450 PF11932.8 ORZ00771.1 - 0.007 15.7 2.3 0.012 15.0 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PT-TG PF14449.6 ORZ00771.1 - 0.064 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Pre-toxin TG zf-Nse PF11789.8 ORZ00771.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CbiG_N PF11760.8 ORZ00771.1 - 0.1 12.6 0.0 0.54 10.3 0.0 2.2 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Sulfatase_C PF14707.6 ORZ00771.1 - 0.24 12.1 0.5 14 6.5 0.1 3.0 3 1 0 3 3 3 0 C-terminal region of aryl-sulfatase Pex24p PF06398.11 ORZ00772.1 - 1.5e-41 142.6 0.1 1.9e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.22 ORZ00772.1 - 2.8e-11 43.1 8.4 5.6e-11 42.1 8.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 ORZ00772.1 - 0.75 9.7 4.6 1.7 8.6 4.6 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 ORZ00772.1 - 2.2 8.2 8.7 6.7 6.7 8.7 1.8 1 0 0 1 1 1 0 PHD-finger SAC3_GANP PF03399.16 ORZ00778.1 - 4.4e-28 98.5 4.4 5.3e-26 91.7 4.4 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 ORZ00778.1 - 2.4e-09 37.3 2.8 8.8e-08 32.2 0.1 2.8 3 1 0 3 3 3 2 CSN8/PSMD8/EIF3K family HTH_18 PF12833.7 ORZ00778.1 - 0.048 13.9 0.0 0.2 12.0 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain SH3_1 PF00018.28 ORZ00779.1 - 1.1e-27 95.4 1.5 1.3e-13 50.3 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORZ00779.1 - 1.4e-24 85.7 1.5 6.1e-12 45.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 ORZ00779.1 - 2.1e-21 76.0 0.0 3.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 ORZ00779.1 - 1e-17 63.6 0.1 6.2e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain F-box-like PF12937.7 ORZ00780.1 - 0.0069 16.3 1.0 0.023 14.6 1.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ00780.1 - 0.011 15.6 0.1 0.011 15.6 0.1 2.0 2 0 0 2 2 2 0 F-box domain Prenyltrans PF00432.21 ORZ00781.1 - 2.5e-43 145.5 9.7 3.9e-09 36.1 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ORZ00781.1 - 1.8e-05 24.0 0.0 0.51 9.4 0.0 3.3 2 1 2 4 4 4 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORZ00781.1 - 0.0007 18.8 0.0 0.41 9.7 0.0 2.6 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain DUF2781 PF10914.8 ORZ00782.1 - 1.4e-43 148.8 10.5 1.6e-43 148.6 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) His_Phos_1 PF00300.22 ORZ00783.1 - 1.5e-40 139.0 0.1 1.6e-40 138.9 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2315 PF10231.9 ORZ00784.1 - 6.5e-16 58.5 0.5 7.8e-16 58.3 0.5 1.1 1 0 0 1 1 1 1 Apoptogenic protein 1 Isochorismatase PF00857.20 ORZ00785.1 - 7.3e-31 107.7 0.1 2e-30 106.3 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.18 ORZ00786.1 - 0.00024 21.1 16.2 0.00041 20.4 16.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PsbW PF07123.12 ORZ00786.1 - 1.8 8.6 4.1 5.5 7.0 4.1 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Herpes_UL56 PF04534.12 ORZ00787.1 - 0.0097 15.4 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Herpesvirus UL56 protein F-box-like PF12937.7 ORZ00788.1 - 0.052 13.4 0.4 0.22 11.4 0.4 2.2 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 ORZ00788.1 - 0.06 13.2 0.5 0.16 11.9 0.5 1.8 1 0 0 1 1 1 0 F-box domain Acyltransferase PF01553.21 ORZ00792.1 - 3e-18 65.7 0.0 5.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Methyltransf_23 PF13489.6 ORZ00793.1 - 3.3e-06 27.1 0.0 3.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ00793.1 - 1.5e-05 25.6 0.0 4.4e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ00793.1 - 8.6e-05 23.2 0.0 0.0002 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ00793.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ00793.1 - 0.0012 19.5 0.0 0.0027 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Nodulin_late PF07127.11 ORZ00796.1 - 0.054 13.8 2.3 0.1 13.0 2.3 1.6 1 1 0 1 1 1 0 Late nodulin protein TRAPPC-Trs85 PF12739.7 ORZ00797.1 - 1.7e-124 415.9 4.2 2.5e-124 415.3 4.2 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 ORZ00797.1 - 2.4e-08 31.9 0.0 7.9e-08 30.2 0.0 1.7 2 0 0 2 2 2 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNAP PF14938.6 ORZ00797.1 - 0.005 16.3 5.1 0.84 9.0 1.0 2.3 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP DUF974 PF06159.13 ORZ00797.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF974) zf-MYND PF01753.18 ORZ00798.1 - 5.6e-07 29.5 19.3 1.7e-06 28.0 19.3 1.9 1 0 0 1 1 1 1 MYND finger DUF2786 PF10979.8 ORZ00799.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) OrfB_Zn_ribbon PF07282.11 ORZ00800.1 - 0.003 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORZ00801.1 - 2.7e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PH PF00169.29 ORZ00803.1 - 1.1e-07 32.3 0.3 2.5e-07 31.1 0.2 1.7 2 0 0 2 2 2 1 PH domain RA PF00788.23 ORZ00803.1 - 0.00012 22.6 0.0 0.0012 19.5 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain CBFB_NFYA PF02045.15 ORZ00804.1 - 3e-27 95.0 8.9 5.2e-27 94.2 8.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Rad60-SLD PF11976.8 ORZ00805.1 - 8.1e-20 70.4 0.6 2.2e-15 56.3 0.2 2.8 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORZ00805.1 - 0.0051 16.5 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family APG6_N PF17675.1 ORZ00805.1 - 0.044 14.3 0.7 0.044 14.3 0.7 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4983 PF16356.5 ORZ00805.1 - 0.077 13.8 1.2 0.16 12.8 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4983) DUF3073 PF11273.8 ORZ00805.1 - 3.2 8.6 0.0 3.2 8.6 0.0 4.4 5 1 0 5 5 5 0 Protein of unknown function (DUF3073) Epimerase PF01370.21 ORZ00806.1 - 1.3e-05 24.8 0.0 6.3e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORZ00806.1 - 2.8e-05 24.1 0.0 0.00024 21.1 0.0 2.2 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 ORZ00806.1 - 0.003 17.1 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ORZ00806.1 - 0.0081 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 ORZ00806.1 - 0.025 13.7 0.0 0.12 11.4 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORZ00806.1 - 0.047 12.7 0.0 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Evr1_Alr PF04777.13 ORZ00807.1 - 4.3e-27 94.5 0.1 5.6e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family FAD_SOX PF18371.1 ORZ00807.1 - 0.0038 17.6 0.0 0.005 17.2 0.0 1.2 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase APOBEC4 PF18775.1 ORZ00807.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 APOBEC4 RNase_H PF00075.24 ORZ00808.1 - 2.9e-12 47.0 0.0 3.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 RNase H Nsp1_C PF05064.13 ORZ00809.1 - 2.2e-36 124.2 8.8 2.2e-36 124.2 8.8 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Med30 PF11315.8 ORZ00809.1 - 0.0053 17.0 7.1 0.011 16.0 7.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit 30 NPV_P10 PF05531.12 ORZ00809.1 - 0.043 14.3 14.5 1 9.9 1.2 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TACC_C PF05010.14 ORZ00809.1 - 0.11 12.3 11.7 0.028 14.2 7.5 1.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 ORZ00809.1 - 0.17 10.5 12.2 0.22 10.1 12.2 1.0 1 0 0 1 1 1 0 AAA domain DUF489 PF04356.12 ORZ00809.1 - 0.17 11.8 4.4 0.2 11.6 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF489) TMPIT PF07851.13 ORZ00809.1 - 0.24 10.6 6.7 0.25 10.5 5.8 1.5 1 1 0 1 1 1 0 TMPIT-like protein Laminin_II PF06009.12 ORZ00809.1 - 0.33 10.9 8.3 0.71 9.9 4.0 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 ORZ00809.1 - 0.36 10.9 12.2 0.64 10.1 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 ORZ00809.1 - 0.57 8.0 7.1 0.7 7.7 6.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF848 PF05852.11 ORZ00809.1 - 0.6 10.2 10.5 7.3 6.7 5.5 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-F_leu_zip PF10473.9 ORZ00809.1 - 1.5 8.8 12.6 1.5 8.8 8.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EMP24_GP25L PF01105.24 ORZ00809.1 - 1.7 8.6 9.5 1.2 9.0 4.4 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4200 PF13863.6 ORZ00809.1 - 2.1 8.8 11.6 1.7 9.1 7.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SOGA PF11365.8 ORZ00809.1 - 3 9.0 5.9 1.5 10.0 1.8 2.4 1 1 2 3 3 3 0 Protein SOGA PsbW PF07123.12 ORZ00810.1 - 0.34 10.9 1.9 0.56 10.2 0.1 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) SUIM_assoc PF16619.5 ORZ00810.1 - 0.97 9.5 23.8 0.064 13.3 7.5 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 ORZ00810.1 - 3.6 7.1 21.9 0.21 11.2 1.4 3.0 3 0 0 3 3 3 0 Spt20 family End3 PF12761.7 ORZ00811.1 - 2.7e-39 135.4 3.4 4e-39 134.9 3.4 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 ORZ00811.1 - 1.2e-30 105.5 0.0 1.4e-27 95.7 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 ORZ00811.1 - 2.3e-08 34.3 61.3 0.0098 16.3 61.3 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 ORZ00811.1 - 4.7e-07 28.9 1.1 1.7e-06 27.2 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORZ00811.1 - 8.7e-05 22.9 0.7 0.00088 19.7 0.0 2.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 ORZ00811.1 - 0.00021 21.0 0.1 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 ORZ00811.1 - 0.00098 18.9 1.4 0.041 13.8 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 ORZ00811.1 - 0.068 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 EF hand Laminin_II PF06009.12 ORZ00811.1 - 0.13 12.3 8.7 0.16 12.0 1.8 2.2 2 0 0 2 2 2 0 Laminin Domain II Cytochrom_B562 PF07361.11 ORZ00811.1 - 0.3 11.8 5.3 0.51 11.0 3.7 2.3 2 1 0 2 2 2 0 Cytochrome b562 DUF3432 PF11914.8 ORZ00811.1 - 0.92 9.8 6.9 1.2 9.4 5.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) SlyX PF04102.12 ORZ00811.1 - 0.98 10.1 10.2 3.8 8.2 0.8 2.8 2 1 0 2 2 2 0 SlyX DUF2203 PF09969.9 ORZ00811.1 - 3.3 8.4 5.9 3.8 8.3 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF16 PF01519.16 ORZ00811.1 - 3.5 8.2 6.7 0.63 10.6 3.1 1.6 2 0 0 2 2 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 ORZ00811.1 - 3.6 7.8 4.9 6.4 7.0 4.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 ORZ00811.1 - 5.3 7.5 8.6 8.4 6.9 0.5 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TFIIA PF03153.13 ORZ00811.1 - 6.4 6.7 13.3 10 6.0 13.1 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S17e PF00833.18 ORZ00812.1 - 5.2e-63 210.4 0.0 6.2e-63 210.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 RNA_pol_A_bac PF01000.26 ORZ00813.1 - 2.2e-30 105.3 0.0 4.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORZ00813.1 - 3.9e-22 77.5 0.0 6.4e-22 76.8 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BOP1NT PF08145.12 ORZ00814.1 - 2.9e-105 351.9 6.5 4.2e-105 351.3 6.5 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 ORZ00814.1 - 4.8e-22 77.8 5.7 2e-06 28.4 0.2 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00814.1 - 2.5e-05 24.5 0.0 1.7 9.0 0.0 4.8 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 ORZ00815.1 - 5.1e-34 115.9 0.3 2.6e-17 62.4 0.0 3.9 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ00815.1 - 5.2e-06 26.5 0.0 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 ORZ00815.1 - 0.00013 21.7 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4614 PF15391.6 ORZ00815.1 - 2.1 8.3 8.3 3.8 7.5 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Glyco_transf_15 PF01793.16 ORZ00816.1 - 2.7e-115 385.1 16.4 3.1e-115 384.9 16.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GATA PF00320.27 ORZ00817.1 - 3.5e-17 61.7 4.0 6.3e-17 60.9 4.0 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 ORZ00817.1 - 5.1e-14 51.8 1.3 1e-13 50.9 1.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_transf_24 PF18404.1 ORZ00818.1 - 2.4e-150 499.3 2.5 4.4e-150 498.5 2.5 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 ORZ00818.1 - 1.9e-56 191.8 1.1 1.1e-55 189.4 0.3 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 ORZ00818.1 - 2.5e-40 138.7 0.6 2.5e-33 115.8 0.2 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 ORZ00818.1 - 3.4e-35 120.5 0.0 1.8e-34 118.2 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 ORZ00818.1 - 3.4e-34 117.7 0.1 7.7e-33 113.3 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 ORZ00818.1 - 8.5e-34 117.1 0.1 1.9e-33 115.9 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 ORZ00818.1 - 2.3e-05 24.1 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 BAF250_C PF12031.8 ORZ00819.1 - 1.7e-08 34.1 0.8 1.5e-07 31.0 0.5 2.7 1 1 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa Sec5 PF15469.6 ORZ00820.1 - 2.3e-55 187.4 1.5 2.3e-55 187.4 1.5 2.6 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 ORZ00820.1 - 2.2e-05 24.4 2.1 8.6e-05 22.5 0.2 2.8 2 0 0 2 2 2 1 Vps51/Vps67 SdrD_B PF17210.3 ORZ00820.1 - 0.084 13.1 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 SdrD B-like domain WD40 PF00400.32 ORZ00821.1 - 1.5e-22 79.5 13.7 1.4e-06 28.9 1.7 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00821.1 - 1.3e-08 35.0 0.0 0.25 11.6 0.1 5.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORZ00821.1 - 0.0017 18.8 0.7 7.7 7.2 0.1 4.2 4 0 0 4 4 4 2 PQQ-like domain Nup160 PF11715.8 ORZ00821.1 - 0.004 15.9 1.0 7.6 5.0 0.0 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORZ00821.1 - 0.027 13.2 0.0 6.2 5.4 0.0 3.3 2 1 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 ORZ00821.1 - 0.065 11.7 0.1 3.5 6.1 0.0 3.0 3 1 1 4 4 4 0 Cytochrome D1 heme domain Hydrolase_4 PF12146.8 ORZ00823.1 - 4.7e-14 52.2 0.0 1.3e-09 37.7 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORZ00823.1 - 2.8e-08 33.8 0.0 0.00012 21.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORZ00823.1 - 7.8e-05 22.2 0.0 0.00037 20.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORZ00823.1 - 0.00058 19.5 0.0 0.0039 16.8 0.0 2.2 1 1 1 2 2 2 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 ORZ00823.1 - 0.00077 19.1 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 ORZ00823.1 - 0.0022 17.8 0.0 0.27 11.0 0.0 2.3 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 ORZ00823.1 - 0.0024 16.6 0.2 0.027 13.1 0.1 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 ORZ00823.1 - 0.0058 15.6 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 ORZ00823.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORZ00823.1 - 0.015 15.9 0.0 0.09 13.4 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family ATP-synt_C PF00137.21 ORZ00823.1 - 0.022 15.1 1.1 0.2 12.0 0.1 2.5 3 0 0 3 3 3 0 ATP synthase subunit C BAAT_C PF08840.11 ORZ00823.1 - 0.038 13.9 0.0 0.92 9.4 0.0 2.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 ORZ00823.1 - 0.046 13.3 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Mustang PF15682.5 ORZ00823.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 MFS_1 PF07690.16 ORZ00824.1 - 1.8e-31 109.4 59.6 1.2e-25 90.2 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORZ00824.1 - 4.1e-08 32.2 15.0 4.1e-08 32.2 15.0 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 ORZ00824.1 - 5.3e-05 22.3 10.1 5.3e-05 22.3 10.1 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORZ00824.1 - 0.044 12.6 23.6 0.12 11.2 5.2 2.7 1 1 1 2 2 2 0 MFS_1 like family MFS_1 PF07690.16 ORZ00825.1 - 1.2e-17 63.9 11.7 1.6e-17 63.5 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORZ00825.1 - 0.00055 19.3 0.8 0.00073 18.9 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 ORZ00825.1 - 0.0015 17.3 0.3 0.0015 17.3 0.3 1.5 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like Ta0938 PF11494.8 ORZ00825.1 - 0.011 16.0 3.1 0.02 15.1 3.1 1.4 1 0 0 1 1 1 0 Ta0938 MFS_1 PF07690.16 ORZ00826.1 - 5.5e-36 124.2 43.3 9.1e-30 103.8 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORZ00826.1 - 3.3e-12 45.7 22.5 1.7e-10 40.0 8.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORZ00826.1 - 0.00045 19.2 13.2 0.02 13.7 1.6 2.7 1 1 2 3 3 3 2 MFS_1 like family MFS_1 PF07690.16 ORZ00828.1 - 4.6e-30 104.7 39.8 8.8e-30 103.8 39.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.28 ORZ00829.1 - 4.2e-64 216.7 0.7 4.6e-38 130.9 0.1 4.2 2 2 0 2 2 2 2 AMP-binding enzyme PCAF_N PF06466.11 ORZ00829.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Cation_efflux PF01545.21 ORZ00830.1 - 7.4e-08 32.4 8.5 1.2e-07 31.7 8.5 1.4 1 0 0 1 1 1 1 Cation efflux family Oxidored_q3 PF00499.20 ORZ00830.1 - 0.021 14.5 0.3 0.052 13.3 0.3 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 GATase PF00117.28 ORZ00831.1 - 1e-11 45.0 0.4 1.2e-05 25.1 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORZ00831.1 - 0.0015 18.3 3.3 0.2 11.4 0.1 2.3 1 1 1 2 2 2 2 Peptidase C26 HTS PF04204.16 ORZ00831.1 - 0.0053 15.7 0.0 0.58 9.0 0.0 2.1 1 1 0 2 2 2 2 Homoserine O-succinyltransferase LPD7 PF18821.1 ORZ00831.1 - 0.0076 16.4 0.0 0.84 9.8 0.0 2.2 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 7 DUF5572 PF17733.1 ORZ00832.1 - 7.6e-23 80.1 2.0 7.6e-23 80.1 2.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5572) MerC PF03203.14 ORZ00833.1 - 0.075 13.5 2.7 0.099 13.1 2.7 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein Myb_DNA-binding PF00249.31 ORZ00834.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORZ00834.1 - 0.003 17.8 0.1 0.0063 16.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Skp1 PF01466.19 ORZ00835.1 - 1.4e-27 95.5 0.6 1.4e-27 95.5 0.6 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 ORZ00835.1 - 2.1e-26 91.8 0.4 7e-26 90.2 0.2 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CofC PF01983.16 ORZ00835.1 - 0.016 14.4 0.6 0.02 14.1 0.6 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like BTB PF00651.31 ORZ00835.1 - 0.13 12.5 0.0 1.2 9.4 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain TPR_1 PF00515.28 ORZ00836.1 - 2.5e-11 42.9 0.0 0.00043 20.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ00836.1 - 8.9e-09 34.8 0.0 0.12 12.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.24 ORZ00836.1 - 1.2e-08 34.7 0.3 2.5e-08 33.7 0.3 1.5 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.6 ORZ00836.1 - 4.1e-06 26.6 0.0 0.00095 19.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ00836.1 - 0.0021 18.7 0.0 1.7 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ00836.1 - 0.012 15.9 0.0 5.6 7.3 0.0 3.4 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ00836.1 - 0.017 15.7 0.0 1e+02 3.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ00836.1 - 0.018 14.7 0.0 0.62 9.8 0.0 2.7 1 1 1 2 2 2 0 TPR repeat TPR_17 PF13431.6 ORZ00836.1 - 0.062 13.7 0.0 7.4 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ00836.1 - 0.078 13.1 0.0 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cse1 PF08506.10 ORZ00838.1 - 1.2e-130 435.7 3.4 1.8e-130 435.0 3.4 1.2 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 ORZ00838.1 - 8.1e-92 308.0 3.2 1.7e-39 135.6 3.1 4.2 2 1 2 4 4 4 3 CAS/CSE protein, C-terminus UBN_AB PF14075.6 ORZ00838.1 - 0.065 13.0 0.2 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Noc2 PF03715.13 ORZ00839.1 - 1.5e-81 273.9 0.0 1.5e-81 273.9 0.0 2.1 2 1 1 3 3 3 1 Noc2p family Nop14 PF04147.12 ORZ00839.1 - 0.00084 17.7 46.8 0.1 10.8 46.2 2.4 2 0 0 2 2 2 2 Nop14-like family BUD22 PF09073.10 ORZ00839.1 - 0.16 11.3 41.3 0.36 10.1 41.3 1.5 1 0 0 1 1 1 0 BUD22 MPC PF03650.13 ORZ00840.1 - 1.1e-35 122.1 0.0 1.3e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers HD PF01966.22 ORZ00841.1 - 2.3e-07 31.1 0.4 5.9e-07 29.7 0.4 1.5 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 ORZ00841.1 - 0.00084 18.9 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 HDOD domain HD_4 PF13328.6 ORZ00841.1 - 0.0039 16.9 2.4 0.009 15.8 2.4 1.7 1 1 0 1 1 1 1 HD domain Hydrolase_6 PF13344.6 ORZ00841.1 - 0.0092 16.1 0.0 0.072 13.2 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HD_6 PF18019.1 ORZ00841.1 - 0.017 15.2 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 HD domain MIOX PF05153.15 ORZ00841.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol oxygenase T3SS_needle_F PF09392.10 ORZ00841.1 - 0.14 12.4 0.2 0.25 11.5 0.2 1.3 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF PhyH PF05721.13 ORZ00842.1 - 2.2e-31 109.8 0.0 2.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORZ00842.1 - 0.00054 20.3 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 ORZ00842.1 - 0.0036 18.2 0.2 0.014 16.2 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ANAPC4 PF12896.7 ORZ00843.1 - 2.2e-24 86.1 2.5 3.3e-24 85.5 2.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 ORZ00844.1 - 1e-13 51.4 0.0 2.2e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 ORZ00846.1 - 4.2e-40 137.8 41.8 6.8e-39 133.8 39.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ00846.1 - 3.3e-11 42.7 8.5 3.3e-11 42.7 8.5 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORZ00846.1 - 4.2e-06 25.5 15.6 5.9e-06 25.0 15.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sec2p PF06428.11 ORZ00847.1 - 1.2e-21 76.5 15.0 1.2e-21 76.5 15.0 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF812 PF05667.11 ORZ00847.1 - 0.00011 21.2 6.4 0.00015 20.8 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DASH_Spc19 PF08287.11 ORZ00847.1 - 0.0025 17.7 15.6 0.0025 17.7 15.6 2.2 1 1 1 2 2 2 1 Spc19 XhlA PF10779.9 ORZ00847.1 - 0.0036 17.5 2.5 0.0036 17.5 2.5 2.8 3 0 0 3 3 3 1 Haemolysin XhlA Fez1 PF06818.15 ORZ00847.1 - 0.0059 17.1 21.9 0.0094 16.4 21.9 1.2 1 0 0 1 1 1 1 Fez1 HAP1_N PF04849.13 ORZ00847.1 - 0.0072 15.6 10.0 0.0072 15.6 10.0 2.2 1 1 1 2 2 2 1 HAP1 N-terminal conserved region DHR10 PF18595.1 ORZ00847.1 - 0.013 15.6 7.9 0.013 15.6 7.9 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 ORZ00847.1 - 0.019 15.0 4.7 0.019 15.0 4.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 ORZ00847.1 - 0.021 14.0 22.2 0.035 13.3 22.2 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein MscS_porin PF12795.7 ORZ00847.1 - 0.029 13.9 19.4 0.41 10.2 1.2 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain PLAC9 PF15205.6 ORZ00847.1 - 0.054 13.9 0.5 0.44 11.0 0.0 2.6 1 1 1 2 2 2 0 Placenta-specific protein 9 CALCOCO1 PF07888.11 ORZ00847.1 - 0.1 11.5 22.7 0.15 10.9 22.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sec3_C_2 PF15278.6 ORZ00847.1 - 0.13 12.6 0.3 0.38 11.1 0.3 1.8 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DUF1729 PF08354.10 ORZ00847.1 - 0.13 11.1 7.7 0.2 10.5 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) YjbH PF06082.11 ORZ00847.1 - 0.2 10.5 3.9 0.25 10.1 3.9 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Tropomyosin_1 PF12718.7 ORZ00847.1 - 0.25 11.5 27.4 0.058 13.5 16.9 2.2 1 1 1 2 2 2 0 Tropomyosin like DUF1515 PF07439.11 ORZ00847.1 - 0.31 11.1 9.9 0.53 10.3 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF4795 PF16043.5 ORZ00847.1 - 0.33 10.5 19.1 0.58 9.7 19.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 ORZ00847.1 - 0.48 10.5 14.3 0.076 13.0 5.3 2.5 1 1 0 2 2 2 0 Laminin Domain II DUF641 PF04859.12 ORZ00847.1 - 0.48 10.8 12.1 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) COG5 PF10392.9 ORZ00847.1 - 0.52 10.5 10.6 6.5 6.9 0.2 3.3 1 1 2 3 3 3 0 Golgi transport complex subunit 5 AAA_13 PF13166.6 ORZ00847.1 - 0.55 8.8 13.1 0.95 8.0 13.1 1.3 1 0 0 1 1 1 0 AAA domain Mod_r PF07200.13 ORZ00847.1 - 0.62 10.2 22.1 0.8 9.8 11.0 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Filament PF00038.21 ORZ00847.1 - 0.65 9.5 25.2 1.4 8.4 4.0 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF4201 PF13870.6 ORZ00847.1 - 1.1 9.0 22.6 0.16 11.7 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Matrilin_ccoil PF10393.9 ORZ00847.1 - 1.4 8.8 6.6 25 4.8 0.6 3.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4407 PF14362.6 ORZ00847.1 - 1.6 8.0 14.9 34 3.7 14.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 ORZ00847.1 - 2.5 8.9 13.0 2.1 9.1 3.1 2.6 1 1 0 2 2 2 0 Occludin homology domain Spc7 PF08317.11 ORZ00847.1 - 3 6.6 25.6 2.6 6.8 17.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4763 PF15960.5 ORZ00847.1 - 3 7.1 22.0 1.2 8.4 5.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) V_ATPase_I PF01496.19 ORZ00847.1 - 3.1 5.6 18.0 0.43 8.4 10.5 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 ORZ00847.1 - 3.4 8.0 7.7 2.9 8.2 0.1 3.1 2 1 1 4 4 2 0 Bacterial protein of unknown function (DUF948) DUF2408 PF10303.9 ORZ00847.1 - 3.6 8.2 12.3 3 8.4 10.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF4200 PF13863.6 ORZ00847.1 - 3.7 8.0 24.0 9.8 6.6 6.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Sec8_exocyst PF04048.14 ORZ00847.1 - 4.5 7.1 9.9 1 9.3 4.2 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain RasGAP_C PF03836.15 ORZ00847.1 - 4.7 7.3 16.9 6.3 6.9 4.8 2.3 1 1 0 2 2 2 0 RasGAP C-terminus TMF_TATA_bd PF12325.8 ORZ00847.1 - 5.6 7.2 27.0 0.3 11.3 12.4 2.6 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 ORZ00847.1 - 5.6 6.4 19.4 4.7 6.7 9.1 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit ADIP PF11559.8 ORZ00847.1 - 6.2 6.9 23.9 5.9 7.0 6.6 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 ORZ00847.1 - 6.3 7.3 9.8 8.7 6.9 3.3 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 ORZ00847.1 - 8.8 6.5 27.8 3.5 7.8 20.7 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 ORZ00847.1 - 8.9 6.2 15.1 3.3 7.5 1.9 3.5 2 1 1 3 3 3 0 Septum formation initiator Velvet PF11754.8 ORZ00849.1 - 1.3e-56 192.4 2.0 4.1e-35 121.9 0.2 2.0 1 1 1 2 2 2 2 Velvet factor AAA_31 PF13614.6 ORZ00849.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 ORZ00850.1 - 2.5e-41 141.4 1.6 3.8e-41 140.8 1.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Brr6_like_C_C PF10104.9 ORZ00850.1 - 7.1e-35 119.7 0.1 1.6e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Helicase_C PF00271.31 ORZ00850.1 - 2.4e-31 108.4 0.2 6.9e-28 97.2 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ00850.1 - 3.5e-09 36.9 0.0 9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORZ00850.1 - 0.04 14.2 1.0 0.059 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 ORZ00850.1 - 0.76 9.2 4.4 0.29 10.6 0.4 2.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain CYSTM PF12734.7 ORZ00851.1 - 2e-05 24.8 41.2 0.0076 16.5 41.2 2.5 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance Extensin_2 PF04554.13 ORZ00851.1 - 2.3 8.4 24.7 14 5.9 24.7 1.9 1 1 0 1 1 1 0 Extensin-like region WD40 PF00400.32 ORZ00853.1 - 2.2e-13 50.4 17.0 0.016 16.1 0.1 6.4 6 1 1 7 7 7 5 WD domain, G-beta repeat Myosin_head PF00063.21 ORZ00855.1 - 2.7e-269 895.0 0.3 5.5e-269 894.1 0.3 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORZ00855.1 - 5.5e-27 94.1 3.6 5.5e-27 94.1 3.6 3.3 3 0 0 3 3 2 1 DIL domain IQ PF00612.27 ORZ00855.1 - 2.5e-18 64.1 25.3 7.7e-05 22.1 0.2 7.4 8 0 0 8 8 7 5 IQ calmodulin-binding motif AAA_13 PF13166.6 ORZ00855.1 - 0.013 14.2 18.0 0.0071 15.1 15.5 1.9 2 0 0 2 2 2 0 AAA domain ADIP PF11559.8 ORZ00855.1 - 0.016 15.3 29.5 0.43 10.7 9.3 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_16 PF13191.6 ORZ00855.1 - 0.045 14.1 0.0 0.045 14.1 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 ORZ00855.1 - 0.049 13.9 0.0 0.049 13.9 0.0 3.5 2 1 1 3 3 3 0 AAA domain Spc7 PF08317.11 ORZ00855.1 - 0.36 9.7 26.9 0.58 9.0 14.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HalX PF08663.10 ORZ00855.1 - 0.42 11.0 17.3 0.91 9.9 0.1 3.5 1 1 2 3 3 3 0 HalX domain Fmp27_WPPW PF10359.9 ORZ00855.1 - 0.5 9.2 16.9 1.1 8.1 16.9 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RPN5_C PF18098.1 ORZ00855.1 - 0.52 10.5 2.5 1.9 8.6 0.5 2.9 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain Seryl_tRNA_N PF02403.22 ORZ00855.1 - 0.67 10.2 22.1 1 9.6 9.9 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 ORZ00855.1 - 0.97 9.7 23.1 2.6 8.3 16.9 3.6 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 ORZ00855.1 - 1.5 8.9 16.9 2.7 8.1 6.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 ORZ00855.1 - 1.7 7.1 13.5 2.8 6.5 12.6 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Myosin_N PF02736.19 ORZ00855.1 - 2.3 8.1 4.5 0.5 10.2 0.9 1.8 2 0 0 2 2 1 0 Myosin N-terminal SH3-like domain DHR10 PF18595.1 ORZ00855.1 - 4.4 7.4 31.5 0.11 12.5 9.7 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain JIP_LZII PF16471.5 ORZ00855.1 - 5.6 7.2 15.6 5.6 7.2 4.8 3.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CENP-F_leu_zip PF10473.9 ORZ00855.1 - 7.3 6.6 26.6 31 4.6 25.9 2.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.10 ORZ00855.1 - 8.7 6.7 23.3 0.3 11.4 7.1 3.6 2 1 1 3 3 2 0 Tup N-terminal GAS PF13851.6 ORZ00855.1 - 8.8 5.6 27.7 4.4 6.6 16.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 ORZ00855.1 - 9.6 5.1 28.6 0.077 11.9 20.2 1.7 2 0 0 2 2 1 0 Intra-flagellar transport protein 57 DUF2340 PF10209.9 ORZ00857.1 - 1.5e-50 170.6 0.4 1.8e-50 170.4 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ubiquitin_4 PF18036.1 ORZ00857.1 - 0.018 15.1 0.1 0.24 11.5 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain Blt1 PF12754.7 ORZ00857.1 - 0.052 13.9 0.0 0.054 13.8 0.0 1.1 1 0 0 1 1 1 0 Blt1 N-terminal domain eIF-3c_N PF05470.12 ORZ00858.1 - 1.2e-177 591.9 16.3 1.2e-177 591.9 16.3 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 ORZ00858.1 - 7.5e-16 58.5 0.0 2.6e-15 56.8 0.0 2.0 1 0 0 1 1 1 1 PCI domain CDC45 PF02724.14 ORZ00858.1 - 0.18 10.1 11.2 0.36 9.1 11.2 1.5 1 0 0 1 1 1 0 CDC45-like protein Drc1-Sld2 PF11719.8 ORZ00859.1 - 1.7e-09 37.7 7.9 1.7e-09 37.7 7.9 2.5 2 1 0 2 2 2 1 DNA replication and checkpoint protein Diphthami_syn_2 PF01902.17 ORZ00860.1 - 5.9e-43 146.9 0.1 1.4e-42 145.7 0.1 1.5 1 1 0 1 1 1 1 Diphthamide synthase BCS1_N PF08740.11 ORZ00861.1 - 3.5e-42 144.5 0.1 5.5e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORZ00861.1 - 4e-20 72.6 0.0 7.2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORZ00861.1 - 0.0043 16.2 0.0 0.0073 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 ORZ00861.1 - 0.03 13.6 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.6 ORZ00861.1 - 0.03 13.9 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORZ00861.1 - 0.037 14.2 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORZ00861.1 - 0.037 13.4 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 ORZ00861.1 - 0.039 14.0 0.0 0.074 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORZ00861.1 - 0.04 14.3 0.1 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ORZ00861.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORZ00861.1 - 0.067 13.6 0.1 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase PBD PF00786.28 ORZ00862.1 - 1.5e-22 79.7 0.9 3.6e-22 78.5 0.1 2.1 2 1 0 2 2 2 1 P21-Rho-binding domain SR-25 PF10500.9 ORZ00862.1 - 1.2 8.6 10.4 2 8.0 10.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 ORZ00863.1 - 6.1e-74 248.7 0.0 8.9e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00863.1 - 1.8e-49 168.4 0.0 2.9e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ00863.1 - 6.1e-06 25.3 0.6 1.4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORZ00863.1 - 3.6e-05 23.2 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORZ00863.1 - 0.016 15.1 0.1 0.16 11.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORZ00863.1 - 0.046 12.7 1.3 0.13 11.2 1.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORZ00863.1 - 0.23 10.8 0.3 0.56 9.5 0.1 1.7 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleoside_tran PF01733.18 ORZ00864.1 - 9.3e-53 179.6 10.4 9.3e-53 179.6 10.4 1.9 1 1 0 2 2 2 1 Nucleoside transporter Rhomboid PF01694.22 ORZ00864.1 - 2.2 8.3 15.8 0.057 13.4 7.1 2.6 2 1 0 2 2 2 0 Rhomboid family Peptidase_M3 PF01432.20 ORZ00865.1 - 4.1e-127 425.2 0.1 5.8e-127 424.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 PhaP_Bmeg PF09602.10 ORZ00865.1 - 0.073 13.0 1.3 0.24 11.3 1.3 1.9 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) zf-H2C2_2 PF13465.6 ORZ00866.1 - 3.3e-08 33.6 1.6 3.3e-08 33.6 1.6 2.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORZ00866.1 - 1.6e-05 25.1 18.3 8.1e-05 22.9 6.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ00866.1 - 7.9e-05 23.2 15.9 0.00063 20.4 4.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORZ00866.1 - 0.028 14.4 9.4 1.1 9.3 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-MYST PF17772.1 ORZ00866.1 - 0.15 11.7 5.8 0.62 9.7 0.4 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain zf-met PF12874.7 ORZ00866.1 - 0.22 12.0 6.2 0.52 10.8 1.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 ORZ00866.1 - 0.92 9.2 6.4 3.8 7.2 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 ORZ00866.1 - 2.4 8.1 13.4 0.3 11.0 7.4 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Phosphodiest PF01663.22 ORZ00867.1 - 3.6e-09 36.7 0.5 3.1e-05 23.7 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Ribosomal_S4e PF00900.20 ORZ00868.1 - 2.6e-37 126.5 0.4 2.6e-37 126.5 0.4 1.6 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORZ00868.1 - 1.1e-25 89.0 0.1 1.9e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORZ00868.1 - 3.9e-19 68.5 8.0 1.6e-18 66.5 8.1 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 ORZ00868.1 - 1.1e-06 28.2 0.1 4.3e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORZ00868.1 - 0.0047 16.8 4.7 0.017 15.1 2.2 3.1 3 1 0 3 3 3 1 KOW motif Pkinase PF00069.25 ORZ00869.1 - 1.6e-62 211.3 0.0 4.1e-62 209.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00869.1 - 5.6e-44 150.4 0.0 9.4e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ00869.1 - 5.8e-07 28.6 0.0 5.8e-07 28.6 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 ORZ00869.1 - 2e-05 24.1 0.0 0.00016 21.1 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 ORZ00869.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family HAD_SAK_1 PF10307.9 ORZ00870.1 - 2.1e-52 177.9 0.0 2.8e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins AAA_16 PF13191.6 ORZ00871.1 - 1.1e-09 38.9 0.0 8.1e-08 32.8 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 ORZ00871.1 - 0.009 15.2 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_12 PF13424.6 ORZ00871.1 - 0.012 15.9 3.3 0.54 10.6 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 ORZ00871.1 - 0.073 13.3 0.0 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain STAS PF01740.21 ORZ00871.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 STAS domain TPR_2 PF07719.17 ORZ00871.1 - 1.6 9.0 5.0 5.1 7.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RsfS PF02410.15 ORZ00872.1 - 2.7e-24 85.4 0.1 6.6e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation FliG_C PF01706.16 ORZ00872.1 - 0.063 13.5 1.1 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 FliG C-terminal domain Endotoxin_C2 PF18449.1 ORZ00872.1 - 0.065 13.6 1.1 0.065 13.6 1.1 1.9 2 0 0 2 2 2 0 Delta endotoxin CHZ PF09649.10 ORZ00872.1 - 1.6 8.3 5.4 1 8.9 1.8 2.4 2 0 0 2 2 2 0 Histone chaperone domain CHZ AA_permease PF00324.21 ORZ00873.1 - 4.2e-116 388.4 41.7 4.8e-116 388.2 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORZ00873.1 - 1.2e-34 119.9 43.9 1.4e-34 119.7 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORZ00874.1 - 7.5e-119 397.4 43.7 9e-119 397.2 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORZ00874.1 - 3.3e-38 131.6 43.2 3.8e-38 131.4 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 ORZ00875.1 - 6.9e-59 199.4 0.0 1.7e-58 198.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00875.1 - 1.2e-41 142.8 0.0 2.1e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ00875.1 - 9.7e-07 27.9 0.0 9.7e-07 27.9 0.0 2.9 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 ORZ00875.1 - 0.00023 20.6 0.0 0.0006 19.2 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORZ00875.1 - 0.11 12.4 2.2 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1666 PF07891.12 ORZ00875.1 - 0.2 11.3 7.2 0.1 12.3 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1666) ArAE_2_N PF10337.9 ORZ00875.1 - 0.26 10.3 6.1 0.51 9.3 6.1 1.4 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal MAT1 PF06391.13 ORZ00875.1 - 1.1 9.1 10.6 2.9 7.7 10.6 1.7 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 ZapB PF06005.12 ORZ00875.1 - 3.9 8.0 19.4 2 8.9 6.5 2.6 2 0 0 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 ORZ00875.1 - 4.4 5.1 8.3 9.3 4.0 8.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sperm_Ag_HE2 PF05324.13 ORZ00876.1 - 0.84 10.1 3.8 0.3 11.6 1.6 1.5 2 1 0 2 2 2 0 Sperm antigen HE2 CAP_GLY PF01302.25 ORZ00877.1 - 1.1e-18 67.0 0.1 3e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 ORZ00877.1 - 1.8e-07 30.9 8.9 0.00037 20.3 1.8 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle TRAF_BIRC3_bd PF16673.5 ORZ00878.1 - 0.011 15.5 6.4 0.58 10.0 0.6 3.4 3 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF3972 PF13118.6 ORZ00878.1 - 0.033 14.6 0.2 0.033 14.6 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3972) Laminin_II PF06009.12 ORZ00878.1 - 0.2 11.7 10.0 2.6 8.1 2.7 3.3 2 1 1 3 3 3 0 Laminin Domain II Cep57_MT_bd PF06657.13 ORZ00878.1 - 0.21 12.1 0.1 0.21 12.1 0.1 3.4 2 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 ORZ00878.1 - 2.3 8.3 19.6 0.84 9.7 2.5 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Radical_SAM_C PF16199.5 ORZ00879.1 - 2.1e-33 114.2 0.1 8.2e-33 112.3 0.0 2.0 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 ORZ00879.1 - 2.2e-19 70.5 0.1 8.4e-19 68.6 0.0 2.0 2 1 1 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 ORZ00879.1 - 9.2e-09 35.6 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORZ00879.1 - 2.7e-06 27.3 0.1 6.8e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORZ00879.1 - 0.021 15.3 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LON_substr_bdg PF02190.16 ORZ00879.1 - 0.12 12.2 0.8 0.32 10.8 0.4 1.8 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain SPATA24 PF15175.6 ORZ00879.1 - 0.27 11.1 0.7 0.45 10.4 0.7 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Dicty_REP PF05086.12 ORZ00880.1 - 0.0041 15.2 1.4 0.0041 15.2 1.4 1.9 2 1 1 3 3 3 1 Dictyostelium (Slime Mold) REP protein Aldedh PF00171.22 ORZ00881.1 - 9.7e-13 47.4 0.7 1.3e-09 37.1 0.2 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Ank_2 PF12796.7 ORZ00882.1 - 1.9e-09 37.9 0.0 0.00049 20.6 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORZ00882.1 - 2.8e-09 37.3 0.3 1.2e-06 29.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ00882.1 - 3e-07 30.2 0.7 0.1 13.2 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat KilA-N PF04383.13 ORZ00882.1 - 4.7e-05 23.2 0.3 0.0018 18.1 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.30 ORZ00882.1 - 0.0014 19.0 0.0 0.87 10.1 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Kinesin_assoc PF16183.5 ORZ00882.1 - 0.24 11.5 2.9 0.4 10.8 0.4 2.3 2 0 0 2 2 2 0 Kinesin-associated HIP1_clath_bdg PF16515.5 ORZ00882.1 - 0.57 10.8 9.2 0.89 10.2 0.3 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PRKG1_interact PF15898.5 ORZ00882.1 - 2.6 9.0 9.3 0.86 10.5 1.9 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain OmpH PF03938.14 ORZ00882.1 - 3 8.2 10.2 0.37 11.1 2.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Insulin PF00049.18 ORZ00882.1 - 3.4 8.8 6.4 1.4 10.0 0.2 2.8 2 1 0 2 2 2 0 Insulin/IGF/Relaxin family Ndc1_Nup PF09531.10 ORZ00882.1 - 9.1 4.8 13.6 4.6 5.8 3.1 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DAO PF01266.24 ORZ00883.1 - 6.1e-50 170.8 0.1 8.2e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORZ00883.1 - 9.1e-06 25.0 0.5 1.9e-05 23.9 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORZ00883.1 - 0.00064 19.9 0.1 0.0023 18.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORZ00883.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 ORZ00883.1 - 0.053 12.1 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 ORZ00883.1 - 0.061 12.6 0.3 7.1 5.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 ORZ00883.1 - 0.11 11.8 0.7 0.28 10.4 0.2 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arrestin_N PF00339.29 ORZ00884.1 - 1.3e-09 38.3 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORZ00884.1 - 0.13 12.0 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Arrestin_N terminal like SSP160 PF06933.11 ORZ00884.1 - 9.6 4.3 11.3 15 3.7 11.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 COX17 PF05051.13 ORZ00885.1 - 2.6e-20 72.5 7.1 3.3e-20 72.1 7.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AA_permease_2 PF13520.6 ORZ00886.1 - 5.5e-51 173.7 53.0 6.9e-51 173.4 53.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORZ00886.1 - 3.1e-39 134.9 44.8 4.3e-39 134.4 44.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORZ00886.1 - 6.9e-06 26.0 8.1 6.9e-06 26.0 8.1 4.0 4 0 0 4 4 4 1 C-terminus of AA_permease PrgI PF12666.7 ORZ00886.1 - 0.048 14.4 1.5 0.048 14.4 1.5 4.9 5 1 0 5 5 5 0 PrgI family protein RA PF00788.23 ORZ00887.1 - 4.1e-13 49.8 0.1 0.00012 22.6 0.0 4.2 4 0 0 4 4 4 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 ORZ00887.1 - 3.6e-07 29.7 0.0 1.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORZ00887.1 - 3.7e-05 23.5 0.0 7.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 ORZ00887.1 - 0.071 13.4 1.9 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial SH3 domain Plasmodium_Vir PF05795.11 ORZ00887.1 - 0.18 11.2 13.7 0.072 12.5 4.2 2.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Spt20 PF12090.8 ORZ00887.1 - 0.44 10.1 14.5 0.32 10.6 5.8 2.8 2 0 0 2 2 2 0 Spt20 family DNA_pol_phi PF04931.13 ORZ00887.1 - 4.7 5.2 45.0 0.34 8.9 21.3 2.3 2 0 0 2 2 2 0 DNA polymerase phi zf-C2H2 PF00096.26 ORZ00888.1 - 5.3e-05 23.4 3.3 0.038 14.5 0.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ00888.1 - 0.021 15.6 1.2 9.7 7.3 0.0 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ00888.1 - 0.19 12.3 5.8 0.41 11.3 0.0 3.1 1 1 1 2 2 2 0 FOXP coiled-coil domain ARID PF01388.21 ORZ00889.1 - 1e-18 67.7 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Ribosomal_S17_N PF16205.5 ORZ00889.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal SKG6 PF08693.10 ORZ00890.1 - 0.00022 20.6 0.9 0.00022 20.6 0.9 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 ORZ00890.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 ORZ00890.1 - 0.03 15.2 0.0 0.1 13.5 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 ORZ00890.1 - 0.087 12.9 1.0 0.15 12.1 1.0 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Adeno_E3_CR2 PF02439.15 ORZ00890.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 ORZ00890.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 1 0 1 1 1 0 Rifin Gram_pos_anchor PF00746.21 ORZ00890.1 - 0.46 10.5 1.9 1.6 8.7 1.9 2.1 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Utp14 PF04615.13 ORZ00890.1 - 0.51 8.8 17.5 0.62 8.6 17.5 1.1 1 0 0 1 1 1 0 Utp14 protein Rick_17kDa_Anti PF05433.15 ORZ00890.1 - 9 6.3 18.6 0.6 10.0 9.2 3.0 3 0 0 3 3 3 0 Glycine zipper 2TM domain Calreticulin PF00262.18 ORZ00891.1 - 4.1e-74 249.6 14.6 1.9e-57 194.8 5.5 2.5 2 1 1 3 3 3 2 Calreticulin family Collagen_bind PF05737.12 ORZ00891.1 - 0.042 14.0 0.7 0.1 12.8 0.7 1.6 1 0 0 1 1 1 0 Collagen binding domain Ribosomal_L37 PF08561.10 ORZ00891.1 - 0.18 12.3 10.9 0.37 11.3 10.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 MDM10 PF12519.8 ORZ00891.1 - 1.8 7.3 6.8 2.6 6.8 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 4HBT PF03061.22 ORZ00892.1 - 5.8e-12 45.8 0.0 8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 ORZ00892.1 - 3.9e-05 23.0 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 ORZ00892.1 - 0.00078 19.9 0.0 0.001 19.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily RabGAP-TBC PF00566.18 ORZ00893.1 - 2.3e-48 164.7 2.0 4.4e-48 163.8 2.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ZapB PF06005.12 ORZ00893.1 - 0.0067 16.9 1.8 0.0067 16.9 1.8 4.3 4 1 1 5 5 5 1 Cell division protein ZapB Peptidase_S78_2 PF14550.6 ORZ00893.1 - 0.014 15.5 0.4 0.026 14.6 0.4 1.4 1 0 0 1 1 1 0 Putative phage serine protease XkdF CENP-H PF05837.12 ORZ00893.1 - 0.22 11.9 21.3 0.14 12.6 4.7 4.2 4 1 1 5 5 5 0 Centromere protein H (CENP-H) YabA PF06156.13 ORZ00893.1 - 2.6 8.7 14.4 4.7 7.9 0.7 3.6 2 1 1 3 3 3 0 Initiation control protein YabA YEATS PF03366.16 ORZ00895.1 - 2.3e-19 69.1 0.1 4.4e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 YEATS family ABC_tran_CTD PF16326.5 ORZ00895.1 - 0.19 12.0 1.9 0.22 11.8 0.5 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain G-alpha PF00503.20 ORZ00896.1 - 1.4e-118 396.1 6.0 1.7e-118 395.9 6.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORZ00896.1 - 3.7e-16 59.1 1.4 3.1e-11 43.0 0.4 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORZ00896.1 - 0.00019 20.9 4.8 0.002 17.5 0.2 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORZ00896.1 - 0.006 16.8 0.3 2.6 8.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 ORZ00896.1 - 0.021 14.6 0.1 0.08 12.8 0.1 2.0 2 0 0 2 2 2 0 CHC2 zinc finger AOX PF01786.17 ORZ00896.1 - 0.029 13.9 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 Alternative oxidase AAA_29 PF13555.6 ORZ00896.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORZ00896.1 - 0.039 13.3 0.0 0.093 12.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ORZ00896.1 - 0.043 13.9 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.25 ORZ00897.1 - 2e-67 227.3 0.0 2.8e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00897.1 - 8.8e-36 123.5 0.0 1.2e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ00897.1 - 1.9e-07 30.7 0.0 2.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORZ00897.1 - 0.00012 21.0 0.0 0.00012 21.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORZ00897.1 - 0.0036 16.7 0.3 0.0071 15.7 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORZ00897.1 - 0.0052 15.8 0.1 0.008 15.2 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 ORZ00897.1 - 0.15 11.0 0.3 0.25 10.2 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Rap_GAP PF02145.15 ORZ00898.1 - 9.6e-49 165.5 0.0 1.5e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP JHY PF15261.6 ORZ00899.1 - 0.049 14.3 0.0 0.049 14.3 0.0 1.9 2 0 0 2 2 2 0 Jhy protein dCMP_cyt_deam_1 PF00383.23 ORZ00900.1 - 8e-26 89.9 1.6 1.3e-25 89.2 1.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORZ00900.1 - 1.6e-12 47.3 0.2 2.9e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 ORZ00900.1 - 0.018 15.6 0.0 0.19 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain Neuroparsin PF07327.11 ORZ00900.1 - 8.4 6.9 12.4 8 7.0 4.8 2.6 1 1 1 2 2 2 0 Neuroparsin Metallophos PF00149.28 ORZ00901.1 - 4.4e-36 125.3 0.1 6.8e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORZ00901.1 - 5.8e-16 58.7 0.1 1.5e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ndc1_Nup PF09531.10 ORZ00901.1 - 0.0062 15.3 5.1 0.0077 15.0 5.1 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 ORZ00901.1 - 0.16 12.0 22.7 0.21 11.6 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORZ00901.1 - 0.87 9.1 21.5 1.4 8.4 21.5 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 ORZ00901.1 - 7.1 4.8 19.1 9.4 4.4 19.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kinesin PF00225.23 ORZ00902.1 - 1.9e-101 339.3 0.8 2.2e-101 339.2 0.8 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORZ00902.1 - 1.4e-18 67.2 0.0 3.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 ORZ00902.1 - 0.059 13.7 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 ORZ00902.1 - 0.067 12.7 0.2 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Pkinase PF00069.25 ORZ00903.1 - 3.4e-71 239.7 0.0 5e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00903.1 - 6.6e-42 143.6 0.0 9.7e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORZ00903.1 - 3.7e-19 68.2 0.2 7.7e-19 67.2 0.2 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORZ00903.1 - 8.2e-07 28.6 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORZ00903.1 - 1.5e-06 28.3 0.2 0.0026 17.7 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORZ00903.1 - 0.00016 20.7 0.1 0.00036 19.6 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORZ00903.1 - 0.00026 20.4 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORZ00903.1 - 0.0063 16.1 0.8 0.01 15.5 0.1 1.7 2 0 0 2 2 2 1 RIO1 family FDC-SP PF15215.6 ORZ00903.1 - 0.11 13.0 0.0 1.1 9.9 0.0 2.7 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide DUF1856 PF08983.10 ORZ00904.1 - 0.067 13.4 1.9 0.067 13.4 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) DUF4448 PF14610.6 ORZ00905.1 - 2.2e-06 27.6 0.2 2.7e-06 27.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SET PF00856.28 ORZ00906.1 - 6.7e-06 26.6 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORZ00906.1 - 1.2e-05 25.3 14.2 1.2e-05 25.3 14.2 2.2 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 ORZ00906.1 - 0.47 10.8 12.0 1.2 9.5 12.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding E1-E2_ATPase PF00122.20 ORZ00907.1 - 4.1e-20 72.1 0.0 9.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORZ00907.1 - 1.1e-17 65.0 0.0 9.3e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ00907.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ00907.1 - 0.015 15.1 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Borrelia_REV PF03978.13 ORZ00907.1 - 0.15 12.0 0.4 0.5 10.3 0.4 1.9 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF3144 PF11342.8 ORZ00908.1 - 0.16 12.3 0.2 0.22 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) CLP_protease PF00574.23 ORZ00909.1 - 3.8e-84 281.1 0.2 4.6e-84 280.8 0.2 1.0 1 0 0 1 1 1 1 Clp protease Rrp15p PF07890.12 ORZ00910.1 - 6e-34 117.3 9.5 6e-34 117.3 9.5 2.8 3 0 0 3 3 3 1 Rrp15p Pes-10 PF07149.11 ORZ00910.1 - 2.1 7.3 11.6 3.5 6.6 11.6 1.3 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 ORZ00910.1 - 4.8 5.3 16.8 5.4 5.2 16.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 ORZ00910.1 - 8.5 4.9 8.6 10 4.7 8.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hydrolase_4 PF12146.8 ORZ00912.1 - 7.8e-10 38.4 0.0 1.4e-08 34.3 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORZ00912.1 - 1.2e-08 35.9 0.2 2.2e-08 35.0 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORZ00912.1 - 1.1e-07 31.8 0.0 4.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ORZ00912.1 - 2.6e-05 24.5 0.0 4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 ORZ00912.1 - 0.0056 16.6 0.1 0.01 15.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 ORZ00912.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3530 PF12048.8 ORZ00912.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF676 PF05057.14 ORZ00912.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.18 ORZ00912.1 - 0.048 13.2 0.0 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 ORZ00912.1 - 0.059 12.2 0.0 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase DUF900 PF05990.12 ORZ00912.1 - 0.2 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_25 PF13649.6 ORZ00913.1 - 6.4e-19 68.5 0.0 1.4e-17 64.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ00913.1 - 2.7e-15 56.6 0.0 4.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ00913.1 - 3.3e-15 56.5 0.0 3.7e-14 53.1 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ00913.1 - 2.5e-12 46.8 0.0 8.1e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ00913.1 - 3e-09 37.5 0.0 1.2e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORZ00913.1 - 3e-06 26.8 0.0 8.8e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 ORZ00913.1 - 0.00028 20.3 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 ORZ00913.1 - 0.0013 18.4 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ORZ00913.1 - 0.012 14.9 0.0 0.063 12.6 0.0 2.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 ORZ00913.1 - 0.02 13.5 0.0 0.079 11.5 0.1 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 ORZ00913.1 - 0.042 14.0 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 ORZ00913.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 ORZ00913.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain bZIP_2 PF07716.15 ORZ00914.1 - 1.9e-11 43.8 8.9 1.9e-11 43.8 8.9 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORZ00914.1 - 1e-09 38.3 15.8 2.7e-09 37.0 11.1 2.4 1 1 1 2 2 2 2 bZIP transcription factor HAP1_N PF04849.13 ORZ00914.1 - 0.0022 17.2 8.7 0.0035 16.6 8.7 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region CLZ PF16526.5 ORZ00914.1 - 0.0074 16.6 5.4 0.014 15.7 5.4 1.5 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_Maf PF03131.17 ORZ00914.1 - 0.0078 16.7 9.9 0.0078 16.7 9.9 2.2 1 1 1 2 2 2 1 bZIP Maf transcription factor ZapB PF06005.12 ORZ00914.1 - 0.0085 16.5 6.6 0.0085 16.5 6.6 2.0 1 1 1 2 2 2 1 Cell division protein ZapB Leu_zip PF15294.6 ORZ00914.1 - 0.019 14.5 8.0 0.026 14.0 8.0 1.1 1 0 0 1 1 1 0 Leucine zipper ABC_tran_CTD PF16326.5 ORZ00914.1 - 0.023 15.0 5.4 0.12 12.7 5.2 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 ORZ00914.1 - 0.027 14.5 10.6 0.045 13.8 10.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HalX PF08663.10 ORZ00914.1 - 0.029 14.7 7.4 0.081 13.2 6.4 2.1 1 1 1 2 2 2 0 HalX domain Striatin PF08232.12 ORZ00914.1 - 0.035 14.7 2.3 0.035 14.7 2.3 2.2 1 1 1 2 2 2 0 Striatin family ATG16 PF08614.11 ORZ00914.1 - 0.046 14.0 18.0 0.05 13.8 16.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Nucleo_P87 PF07267.11 ORZ00914.1 - 0.054 12.3 4.6 0.062 12.2 4.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Put_Phosphatase PF06888.12 ORZ00914.1 - 0.07 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase Nup54 PF13874.6 ORZ00914.1 - 0.077 13.1 9.1 0.13 12.4 9.1 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ADIP PF11559.8 ORZ00914.1 - 0.11 12.6 11.3 0.069 13.2 9.4 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CtIP_N PF10482.9 ORZ00914.1 - 0.12 12.4 7.1 0.18 11.8 5.3 1.9 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF3450 PF11932.8 ORZ00914.1 - 0.13 11.5 8.8 0.21 10.9 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 ORZ00914.1 - 0.14 12.1 5.5 0.46 10.4 0.5 3.1 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Jnk-SapK_ap_N PF09744.9 ORZ00914.1 - 0.15 12.3 13.3 0.23 11.7 13.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Hemagglutinin PF00509.18 ORZ00914.1 - 0.15 10.4 1.4 0.18 10.1 1.4 1.1 1 0 0 1 1 1 0 Haemagglutinin FlaC_arch PF05377.11 ORZ00914.1 - 0.28 11.6 2.1 0.74 10.3 2.0 1.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 ORZ00914.1 - 0.31 11.3 10.8 0.48 10.7 10.8 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 ORZ00914.1 - 0.32 8.9 1.6 0.37 8.7 1.6 1.1 1 0 0 1 1 1 0 Prominin XhlA PF10779.9 ORZ00914.1 - 0.37 11.0 3.5 1.2 9.4 3.4 1.9 1 1 0 1 1 1 0 Haemolysin XhlA DUF2730 PF10805.8 ORZ00914.1 - 0.4 10.8 3.3 0.69 10.0 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3552 PF12072.8 ORZ00914.1 - 0.76 9.2 17.3 1 8.7 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1515 PF07439.11 ORZ00914.1 - 0.77 9.8 3.1 0.94 9.5 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4988 PF16378.5 ORZ00914.1 - 0.81 9.3 2.4 7 6.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function MPS2 PF17060.5 ORZ00914.1 - 1.2 8.3 6.6 1.7 7.8 6.6 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF724 PF05266.14 ORZ00914.1 - 1.6 8.6 9.2 2.2 8.1 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 ORZ00914.1 - 2 7.2 10.9 2.7 6.8 10.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 ORZ00914.1 - 2.3 8.5 8.2 14 6.0 8.2 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HAUS-augmin3 PF14932.6 ORZ00914.1 - 2.8 7.5 11.0 3.8 7.0 11.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF5595 PF18077.1 ORZ00914.1 - 3.5 7.8 5.3 2.3 8.3 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DUF4140 PF13600.6 ORZ00914.1 - 4.7 7.7 11.7 5.7 7.5 3.0 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Paralemmin PF03285.15 ORZ00914.1 - 5.6 6.4 10.2 0.29 10.7 4.8 1.6 2 0 0 2 2 1 0 Paralemmin NAM-associated PF14303.6 ORZ00914.1 - 5.9 7.6 11.7 0.28 11.9 6.2 1.5 2 0 0 2 2 1 0 No apical meristem-associated C-terminal domain Tetraspanin PF00335.20 ORZ00915.1 - 0.022 14.5 15.9 1.4 8.5 13.5 2.2 2 0 0 2 2 2 0 Tetraspanin family SRTM1 PF15872.5 ORZ00915.1 - 1.4 9.1 5.8 0.3 11.2 0.9 2.3 2 1 1 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 LRR19-TM PF15176.6 ORZ00915.1 - 1.6 8.7 6.7 1.5 8.9 0.1 2.7 2 1 1 3 3 3 0 Leucine-rich repeat family 19 TM domain Bac_surface_Ag PF01103.23 ORZ00916.1 - 3.5e-45 154.9 0.5 4.9e-45 154.4 0.5 1.1 1 0 0 1 1 1 1 Surface antigen ABC_trans_N PF14510.6 ORZ00916.1 - 0.087 13.4 0.1 0.33 11.6 0.1 2.0 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_assoc PF14363.6 ORZ00916.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA p450 PF00067.22 ORZ00917.1 - 6.5e-87 292.2 0.0 8.2e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ASFV_L11L PF05293.11 ORZ00917.1 - 0.028 14.8 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein ANAPC4_WD40 PF12894.7 ORZ00918.1 - 6.6e-05 23.1 0.0 0.091 13.1 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 ORZ00918.1 - 0.0037 16.9 0.2 1.1 8.8 0.0 2.9 4 0 0 4 4 4 2 CNH domain WD40 PF00400.32 ORZ00918.1 - 0.018 15.9 0.1 0.44 11.5 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 ORZ00918.1 - 0.047 12.7 0.0 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region Hira PF07569.11 ORZ00918.1 - 0.15 11.8 0.1 5 6.8 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split UCH PF00443.29 ORZ00919.1 - 1.1e-48 165.9 0.5 2.7e-48 164.7 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 ORZ00919.1 - 2.3e-36 125.4 6.2 8.1e-36 123.7 0.7 3.1 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 ORZ00919.1 - 1.2e-29 103.3 0.2 4.3e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 ORZ00919.1 - 1.6e-23 83.8 0.0 1e-22 81.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORZ00919.1 - 2.1e-05 24.6 0.0 0.00016 21.8 0.0 2.4 2 0 0 2 2 2 1 MATH domain Mcp5_PH PF12814.7 ORZ00920.1 - 4.6e-29 101.0 0.0 1.1e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ING PF12998.7 ORZ00920.1 - 3.3 8.4 12.5 0.4 11.3 4.0 3.6 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding zf-CCCH_2 PF14608.6 ORZ00921.1 - 1.5e-09 38.0 16.4 0.00017 21.9 1.9 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 ORZ00921.1 - 0.0029 17.3 8.7 0.0045 16.8 1.6 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 ORZ00921.1 - 0.017 15.0 1.6 0.017 15.0 1.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORZ00921.1 - 0.19 11.8 8.7 0.2 11.8 2.0 2.7 2 0 0 2 2 2 0 Zinc finger domain Prefoldin_2 PF01920.20 ORZ00922.1 - 1.5e-26 92.4 3.5 1.7e-26 92.2 3.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit EzrA PF06160.12 ORZ00922.1 - 0.00069 17.9 2.4 0.21 9.7 0.3 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 ORZ00922.1 - 0.0018 18.3 3.3 0.068 13.2 0.4 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 ORZ00922.1 - 0.0046 16.2 1.5 0.13 11.5 0.1 2.0 2 0 0 2 2 2 1 Myosin-like coiled-coil protein IFT57 PF10498.9 ORZ00922.1 - 0.0095 14.9 4.0 0.21 10.5 0.4 2.0 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 Turandot PF07240.11 ORZ00922.1 - 0.014 15.4 0.7 0.048 13.6 0.1 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot ATPase PF06745.13 ORZ00922.1 - 0.016 14.6 0.1 0.025 14.0 0.1 1.4 1 1 0 1 1 1 0 KaiC DUF148 PF02520.17 ORZ00922.1 - 0.022 14.9 2.9 0.39 10.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 ORZ00922.1 - 0.06 13.4 0.1 4.7 7.2 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5595 PF18077.1 ORZ00922.1 - 0.067 13.3 7.2 0.76 9.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) ATG19_autophagy PF12744.7 ORZ00922.1 - 0.07 12.3 1.7 0.081 12.1 0.1 1.7 2 0 0 2 2 2 0 Autophagy protein Atg19, Atg8-binding BLOC1_2 PF10046.9 ORZ00922.1 - 0.089 13.1 3.2 0.74 10.2 0.5 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.19 ORZ00922.1 - 0.092 12.4 5.1 0.34 10.6 0.2 2.0 2 0 0 2 2 2 0 GrpE Tektin PF03148.14 ORZ00922.1 - 0.11 11.2 2.3 1.9 7.2 0.4 2.0 2 0 0 2 2 2 0 Tektin family CPT_N PF16484.5 ORZ00922.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus ABC_tran_CTD PF16326.5 ORZ00922.1 - 0.23 11.7 4.3 0.48 10.7 1.6 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain OmpH PF03938.14 ORZ00922.1 - 0.93 9.8 8.6 12 6.2 8.6 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.8 ORZ00922.1 - 2.8 8.0 8.3 1.1 9.4 3.3 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MIT PF04212.18 ORZ00923.1 - 8.3e-07 29.0 0.7 1.9e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF4946 PF16304.5 ORZ00923.1 - 0.012 15.3 1.5 2 8.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4946) COQ9 PF08511.11 ORZ00923.1 - 0.013 15.2 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 COQ9 MFS_1 PF07690.16 ORZ00925.1 - 1.4e-26 93.2 15.3 1.6e-26 93.1 15.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ00925.1 - 6.8e-13 48.3 11.8 8.2e-13 48.0 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORZ00925.1 - 8.5e-08 31.1 7.2 9.5e-08 30.9 7.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORZ00925.1 - 0.00019 20.0 5.3 0.00021 19.8 5.3 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector DUF5325 PF17259.2 ORZ00925.1 - 0.0018 18.1 1.0 0.0018 18.1 1.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5325) Fzo_mitofusin PF04799.13 ORZ00925.1 - 0.03 13.9 1.3 0.045 13.3 1.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region MFS_1 PF07690.16 ORZ00926.1 - 0.0096 14.9 5.1 4.1 6.2 0.4 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily SUI1 PF01253.22 ORZ00927.1 - 1.4e-21 76.8 0.3 1.4e-21 76.8 0.3 1.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 BAR_2 PF10455.9 ORZ00927.1 - 0.0082 15.3 0.1 0.0089 15.2 0.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Syntaxin PF00804.25 ORZ00928.1 - 6.4e-37 127.2 16.2 6.4e-37 127.2 16.2 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 ORZ00928.1 - 1e-12 47.8 0.9 2.2e-12 46.8 0.9 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 ORZ00928.1 - 6.6e-06 26.4 4.6 6.6e-06 26.4 4.6 2.6 2 2 0 2 2 2 1 Syntaxin-like protein MCU PF04678.13 ORZ00928.1 - 0.0016 18.5 2.3 0.0016 18.5 2.3 2.4 1 1 0 2 2 2 1 Mitochondrial calcium uniporter SKA1 PF07160.12 ORZ00928.1 - 0.016 15.0 4.0 0.016 15.0 4.0 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Vac_Fusion PF02346.16 ORZ00928.1 - 0.04 13.5 0.5 0.04 13.5 0.5 2.5 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF4094 PF13334.6 ORZ00928.1 - 0.081 13.3 0.5 0.081 13.3 0.5 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) DUF4988 PF16378.5 ORZ00928.1 - 0.22 11.2 6.8 0.65 9.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function LMBR1 PF04791.16 ORZ00928.1 - 0.24 10.2 14.4 0.81 8.5 14.4 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein PDCD7 PF16021.5 ORZ00928.1 - 0.39 9.8 9.8 0.31 10.1 0.7 2.5 2 1 1 3 3 3 0 Programmed cell death protein 7 DUF1759 PF03564.15 ORZ00928.1 - 0.69 9.8 9.3 0.15 12.0 1.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) Synaptobrevin PF00957.21 ORZ00928.1 - 1.7 8.5 16.9 1.5 8.7 3.3 3.2 3 0 0 3 3 3 0 Synaptobrevin Neur_chan_memb PF02932.16 ORZ00928.1 - 1.9 8.5 5.3 0.65 10.0 2.6 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MCPsignal PF00015.21 ORZ00928.1 - 2 8.2 9.3 0.36 10.6 1.7 2.8 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 ORZ00928.1 - 8.8 6.3 10.9 0.97 9.4 2.2 2.8 2 2 1 3 3 3 0 Laminin Domain II LIM PF00412.22 ORZ00929.1 - 1e-32 112.1 26.9 2.8e-12 46.7 3.7 3.2 3 0 0 3 3 3 3 LIM domain WRC PF08879.10 ORZ00929.1 - 0.019 14.6 5.6 1.9 8.2 0.2 3.2 3 0 0 3 3 3 0 WRC RecO_C PF02565.15 ORZ00929.1 - 4.1 7.2 9.7 3.4 7.5 0.5 3.0 3 0 0 3 3 3 0 Recombination protein O C terminal NTP_transferase PF00483.23 ORZ00931.1 - 8.1e-29 100.9 0.0 1.1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORZ00931.1 - 1.8e-09 36.9 8.8 9.8e-06 25.1 0.6 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORZ00931.1 - 1.5e-07 31.9 0.0 3.2e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.12 ORZ00931.1 - 0.012 14.6 0.3 0.16 10.9 0.2 2.2 2 0 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 ORZ00931.1 - 0.012 13.7 0.3 0.024 12.8 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Ntox30 PF15532.6 ORZ00931.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 30 CK_II_beta PF01214.18 ORZ00932.1 - 6.1e-83 277.1 0.1 8.4e-83 276.6 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 ORZ00932.1 - 0.039 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Glyco_hydro_100 PF12899.7 ORZ00932.1 - 0.085 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase Borrelia_orfA PF02414.15 ORZ00932.1 - 0.24 11.0 4.1 6 6.4 0.3 2.1 2 0 0 2 2 2 0 Borrelia ORF-A M-factor PF03855.13 ORZ00932.1 - 5.3 7.3 5.5 33 4.7 3.2 2.9 3 0 0 3 3 3 0 M-factor Fz PF01392.22 ORZ00933.1 - 0.00048 20.7 0.4 0.00067 20.2 0.4 1.1 1 0 0 1 1 1 1 Fz domain DUF1206 PF06724.11 ORZ00933.1 - 0.042 13.9 0.7 0.062 13.4 0.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Frizzled PF01534.17 ORZ00934.1 - 5.8e-11 42.0 15.6 7.8e-11 41.6 15.6 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 ORZ00934.1 - 9.8e-07 28.3 14.3 1.5e-06 27.7 14.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Strabismus PF06638.11 ORZ00934.1 - 0.03 13.0 1.1 0.052 12.2 1.1 1.3 1 0 0 1 1 1 0 Strabismus protein 7tm_1 PF00001.21 ORZ00934.1 - 0.045 13.1 11.8 0.09 12.1 11.8 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PspB PF06667.12 ORZ00934.1 - 0.23 11.5 8.7 0.53 10.4 1.2 2.9 2 1 1 3 3 3 0 Phage shock protein B CaKB PF03185.15 ORZ00934.1 - 0.51 10.0 3.9 15 5.2 0.2 3.1 3 0 0 3 3 3 0 Calcium-activated potassium channel, beta subunit Sec6 PF06046.13 ORZ00935.1 - 1.7e-147 492.2 9.2 1.7e-147 492.2 9.2 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 SesA PF17107.5 ORZ00935.1 - 0.0053 16.9 4.6 4.7 7.4 0.0 5.2 6 0 0 6 6 6 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Fib_alpha PF08702.10 ORZ00935.1 - 0.0071 16.5 4.0 0.03 14.5 4.0 2.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 ORZ00935.1 - 0.036 14.4 4.2 0.16 12.4 4.2 2.2 1 0 0 1 1 1 0 Syntaxin-like protein ApoLp-III PF07464.11 ORZ00935.1 - 0.12 12.5 5.6 0.26 11.4 3.7 2.6 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF5601 PF18151.1 ORZ00935.1 - 0.13 12.6 4.8 23 5.4 0.3 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5601) SLIDE PF09111.10 ORZ00935.1 - 0.17 12.0 6.6 0.055 13.5 0.6 2.7 3 0 0 3 3 3 0 SLIDE Vps53_N PF04100.12 ORZ00935.1 - 0.56 9.1 9.6 0.38 9.7 2.5 2.8 2 1 0 2 2 2 0 Vps53-like, N-terminal COG2 PF06148.11 ORZ00935.1 - 1.7 8.8 8.7 5.7 7.0 0.1 3.8 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 SOAR PF16533.5 ORZ00935.1 - 3.2 7.8 12.7 0.066 13.2 1.0 3.9 4 1 1 5 5 5 0 STIM1 Orai1-activating region CSN8_PSD8_EIF3K PF10075.9 ORZ00936.1 - 6.4e-21 74.8 0.0 1.3e-20 73.9 0.0 1.4 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 ORZ00936.1 - 0.023 15.2 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 PCI domain PQQ_3 PF13570.6 ORZ00937.1 - 0.0009 19.7 1.9 0.0059 17.1 0.2 3.2 3 1 0 3 3 3 1 PQQ-like domain SR-25 PF10500.9 ORZ00938.1 - 6.1 6.4 18.3 9.8 5.7 18.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.16 ORZ00939.1 - 7.1e-23 81.1 37.6 7.1e-23 81.1 37.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 ORZ00939.1 - 0.092 12.5 0.1 0.092 12.5 0.1 2.8 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Vma12 PF11712.8 ORZ00939.1 - 1.2 9.2 4.3 21 5.2 0.1 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ABC_membrane PF00664.23 ORZ00940.1 - 2.7e-50 171.5 21.5 5.3e-33 114.8 9.7 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORZ00940.1 - 3.8e-24 85.8 0.0 1.2e-11 45.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 ORZ00940.1 - 0.006 16.2 0.0 0.038 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ecl1 PF12855.7 ORZ00941.1 - 3.2e-12 48.0 11.3 4e-12 47.7 11.3 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 ORZ00941.1 - 0.00046 20.2 0.8 0.00046 20.2 0.8 1.7 2 0 0 2 2 2 1 MYND finger SR-25 PF10500.9 ORZ00941.1 - 3.2 7.3 5.6 3.6 7.1 5.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DEAD PF00270.29 ORZ00942.1 - 2.2e-45 154.6 0.0 3.1e-44 150.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ00942.1 - 9.3e-31 106.5 0.1 2.4e-28 98.7 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ00942.1 - 7.5e-05 22.8 0.0 0.0088 16.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 ORZ00942.1 - 0.0011 19.0 2.6 0.0018 18.2 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Helicase_C_2 PF13307.6 ORZ00942.1 - 0.15 12.2 2.1 8 6.6 0.0 2.7 3 0 0 3 3 3 0 Helicase C-terminal domain zf-CCHC_2 PF13696.6 ORZ00942.1 - 0.18 11.6 2.4 0.37 10.7 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 ORZ00942.1 - 0.19 11.5 2.0 0.34 10.7 0.9 1.9 2 0 0 2 2 2 0 Zinc knuckle SAM_1 PF00536.30 ORZ00943.1 - 0.028 14.8 0.0 0.056 13.9 0.0 1.5 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORZ00943.1 - 0.096 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HMG_box PF00505.19 ORZ00944.1 - 1.2e-14 54.4 3.6 3.2e-14 53.1 3.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ00944.1 - 1.8e-11 44.4 5.9 2.8e-11 43.8 5.3 1.7 1 1 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 ORZ00944.1 - 0.0013 18.9 2.4 0.0026 17.9 2.4 1.5 1 0 0 1 1 1 1 Protamine and protamine like WYL_3 PF18488.1 ORZ00944.1 - 0.053 13.9 1.9 0.12 12.8 1.9 1.5 1 0 0 1 1 1 0 WYL domain DUF512 PF04459.12 ORZ00944.1 - 0.87 8.8 2.7 1.4 8.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF4258 PF14076.6 ORZ00944.1 - 1.1 9.7 2.6 0.83 10.1 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Mit_ribos_Mrp51 PF11709.8 ORZ00946.1 - 6.6e-15 55.6 10.0 3.4e-10 40.1 1.6 4.0 2 1 1 3 3 3 3 Mitochondrial ribosomal protein subunit DUF4051 PF13260.6 ORZ00946.1 - 0.066 13.0 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) PDEase_I_N PF08499.12 ORZ00946.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal S1 PF00575.23 ORZ00946.1 - 0.097 13.0 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 S1 RNA binding domain zf-C2H2 PF00096.26 ORZ00947.1 - 1.7e-11 43.9 16.8 1.8e-06 28.1 4.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ00947.1 - 1.9e-07 31.2 16.9 9.7e-06 25.8 4.6 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ00947.1 - 1.8e-06 28.3 14.7 0.0042 17.8 1.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORZ00947.1 - 0.0082 16.3 4.1 0.024 14.8 4.1 1.7 1 1 0 1 1 1 1 Aberrant zinc-finger zf-met PF12874.7 ORZ00947.1 - 0.015 15.7 3.4 2 8.9 1.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 ORZ00947.1 - 0.034 14.2 0.9 0.034 14.2 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger FOXP-CC PF16159.5 ORZ00947.1 - 0.053 14.2 3.3 1.1 10.0 0.5 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORZ00947.1 - 0.13 12.6 7.8 0.73 10.2 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 ORZ00947.1 - 0.36 10.8 2.7 13 5.7 0.7 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger HLH PF00010.26 ORZ00948.1 - 1.9e-14 53.3 1.7 4.3e-14 52.2 1.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MAGE_N PF12440.8 ORZ00948.1 - 0.03 15.0 1.4 0.03 15.0 1.4 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF5094 PF17015.5 ORZ00948.1 - 0.66 10.1 5.9 1 9.4 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) FUSC PF04632.12 ORZ00948.1 - 0.87 8.0 3.2 0.98 7.9 3.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 ORZ00948.1 - 1.6 9.0 13.3 0.057 13.6 4.3 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 ORZ00948.1 - 2.5 8.5 7.9 5.4 7.4 8.0 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2570 PF10828.8 ORZ00948.1 - 5.9 6.8 8.2 0.69 9.8 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Rotamase PF00639.21 ORZ00950.1 - 2e-23 83.2 0.0 2.6e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ORZ00950.1 - 5.7e-20 72.0 0.0 6.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 ORZ00950.1 - 9.4e-09 35.2 1.5 2.4e-08 33.9 1.5 1.7 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 ORZ00950.1 - 0.0011 19.8 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain ApoLp-III PF07464.11 ORZ00950.1 - 0.074 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PEPcase_2 PF14010.6 ORZ00950.1 - 0.084 11.4 0.1 0.091 11.3 0.1 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF3759 PF12585.8 ORZ00951.1 - 2.6e-25 88.3 12.2 4.7e-25 87.4 12.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.6 ORZ00951.1 - 0.00047 20.8 0.0 0.013 16.2 0.0 2.6 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ORZ00951.1 - 0.00067 19.9 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF1459 PF07312.11 ORZ00951.1 - 0.042 14.1 1.5 8.3 6.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) AMP-binding PF00501.28 ORZ00952.1 - 1.5e-74 251.1 0.1 1.9e-74 250.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ00952.1 - 3.2e-11 44.0 0.0 6.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 ORZ00953.1 - 3.9e-24 85.5 0.0 1.7e-23 83.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II GNAT_C PF18164.1 ORZ00953.1 - 0.075 12.7 0.4 1.3 8.7 0.5 2.5 3 0 0 3 3 3 0 GNAT-like C-terminal domain PEX-2N PF09263.10 ORZ00953.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal PRP38 PF03371.15 ORZ00955.1 - 5.3e-46 156.7 0.1 7e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 PRP38 family ADH_N PF08240.12 ORZ00956.1 - 2e-31 108.1 0.6 2e-31 108.1 0.6 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ00956.1 - 1.9e-18 66.7 0.1 2.8e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ00956.1 - 4.6e-07 31.0 0.0 8.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORZ00956.1 - 1.3e-05 24.8 0.9 0.00062 19.3 0.9 2.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORZ00956.1 - 0.00036 19.9 0.1 0.00063 19.1 0.1 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ORZ00956.1 - 0.0046 16.3 0.1 0.0091 15.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 ORZ00956.1 - 0.0055 16.8 1.6 0.085 12.9 0.2 2.5 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.14 ORZ00956.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORZ00956.1 - 0.032 13.0 0.8 0.048 12.4 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_25 PF13649.6 ORZ00956.1 - 0.038 14.7 0.0 0.073 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FHA PF00498.26 ORZ00959.1 - 6.7e-17 61.6 0.0 2e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 ORZ00959.1 - 2.9e-05 24.3 0.0 0.00014 22.1 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Methyltransf_11 PF08241.12 ORZ00960.1 - 8.5e-16 58.4 0.0 1.6e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ00960.1 - 7.4e-13 49.0 0.0 8.9e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ00960.1 - 7.8e-11 42.1 0.0 9.7e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ00960.1 - 1.9e-07 31.8 0.0 3.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ00960.1 - 4.6e-07 29.4 0.0 1.2e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORZ00960.1 - 0.00071 19.4 0.0 0.0049 16.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 ORZ00960.1 - 0.0015 17.2 0.0 0.002 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 ORZ00960.1 - 0.003 17.4 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORZ00960.1 - 0.0071 15.9 0.1 0.12 11.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 ORZ00960.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase SCAN PF02023.17 ORZ00960.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 SCAN domain RrnaAD PF00398.20 ORZ00960.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 ORZ00960.1 - 0.039 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ESX-1_EspG PF14011.6 ORZ00960.1 - 0.048 13.3 0.3 0.062 12.9 0.3 1.1 1 0 0 1 1 1 0 EspG family zf-ZPR1 PF03367.13 ORZ00961.1 - 3.4e-115 381.3 0.1 1.3e-56 190.9 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 ORZ00961.1 - 0.0044 17.0 3.0 1.1 9.3 0.6 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 ORZ00961.1 - 0.12 12.5 4.2 3.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 ORZ00961.1 - 0.25 11.5 7.6 1.8 8.8 0.2 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 ORZ00961.1 - 0.63 10.1 5.5 3.4 7.7 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbons OrfB_Zn_ribbon PF07282.11 ORZ00961.1 - 0.7 9.9 5.5 1.4 8.9 0.2 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain C1_1 PF00130.22 ORZ00961.1 - 1.1 9.2 4.1 1.2 9.0 0.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF983 PF06170.12 ORZ00961.1 - 2.1 8.8 3.6 1.3e+02 3.1 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF983) Lar_restr_allev PF14354.6 ORZ00961.1 - 4.8 7.6 12.6 0.39 11.1 0.4 3.1 3 1 0 3 3 3 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 ORZ00961.1 - 4.9 6.7 9.6 10 5.7 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 ORZ00961.1 - 6 6.7 6.7 12 5.7 0.1 3.6 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_4 PF13894.6 ORZ00961.1 - 6.8 7.8 7.4 19 6.4 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger DZR PF12773.7 ORZ00961.1 - 7.3 6.7 11.9 3.9 7.6 2.1 3.3 2 2 1 3 3 3 0 Double zinc ribbon UPF0547 PF10571.9 ORZ00961.1 - 7.8 6.7 9.4 1.7 8.8 0.3 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Glyco_transf_49 PF13896.6 ORZ00962.1 - 2e-63 214.8 1.0 1.4e-50 172.6 1.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 ORZ00962.1 - 0.019 15.5 0.4 0.055 14.0 0.4 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ORZ00962.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 LRR_6 PF13516.6 ORZ00963.1 - 0.00068 19.5 0.4 0.61 10.3 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 ORZ00963.1 - 0.0016 18.8 3.8 4.3 7.9 0.1 5.5 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) Fer2_BFD PF04324.15 ORZ00963.1 - 0.5 10.8 2.9 29 5.1 0.0 4.1 5 0 0 5 5 5 0 BFD-like [2Fe-2S] binding domain Methyltransf_25 PF13649.6 ORZ00965.1 - 3.5e-17 62.9 0.0 5.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ00965.1 - 5.2e-15 55.7 0.0 6.4e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ00965.1 - 3.2e-14 53.3 0.0 4.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ00965.1 - 2.9e-13 49.9 0.0 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ00965.1 - 7.3e-10 39.5 0.0 1.6e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORZ00965.1 - 2.9e-07 30.1 0.0 9.7e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 ORZ00965.1 - 2e-06 27.3 0.0 7.9e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORZ00965.1 - 3.4e-05 23.8 0.0 6.5e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 ORZ00965.1 - 0.00063 18.4 0.0 0.0093 14.6 0.0 2.0 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 ORZ00965.1 - 0.0058 16.0 0.0 0.0092 15.3 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 ORZ00965.1 - 0.01 15.4 0.0 0.023 14.2 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 ORZ00965.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.18 ORZ00965.1 - 0.013 15.0 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain MetW PF07021.12 ORZ00965.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_20 PF12147.8 ORZ00965.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.12 ORZ00965.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF938) CTC1 PF15489.6 ORZ00965.1 - 0.19 9.2 0.0 0.23 9.0 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 PrmA PF06325.13 ORZ00965.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 ORZ00965.1 - 0.19 10.9 0.0 15 4.6 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family HSP70 PF00012.20 ORZ00967.1 - 2.6e-08 32.5 0.0 1.6e-06 26.7 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ORZ00967.1 - 0.033 13.0 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.25 ORZ00968.1 - 1.3e-69 234.5 0.0 3.8e-69 233.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00968.1 - 1.1e-42 146.2 0.0 1.9e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORZ00968.1 - 1.8e-18 66.1 0.0 3.5e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.22 ORZ00968.1 - 1.3e-05 24.8 0.1 2.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 ORZ00968.1 - 1.8e-05 24.2 0.0 4.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORZ00968.1 - 6.1e-05 22.1 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORZ00968.1 - 0.00012 22.1 0.6 0.0032 17.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 ORZ00968.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Succ_DH_flav_C PF02910.20 ORZ00968.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term YrbL-PhoP_reg PF10707.9 ORZ00968.1 - 0.13 11.8 0.2 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL WD40 PF00400.32 ORZ00969.1 - 1.8e-23 82.3 2.0 8.8e-06 26.4 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ00969.1 - 7.4e-10 39.0 0.0 0.00011 22.4 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORZ00969.1 - 2.5e-06 26.7 0.0 0.026 13.5 0.0 3.1 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 ORZ00969.1 - 0.04 13.7 0.0 1.5 8.5 0.0 2.9 3 1 0 3 3 3 0 TUP1-like enhancer of split PQQ_3 PF13570.6 ORZ00969.1 - 0.061 13.8 0.4 18 6.0 0.0 4.1 4 1 1 5 5 5 0 PQQ-like domain Nup160 PF11715.8 ORZ00969.1 - 0.088 11.4 0.1 17 3.9 0.0 3.1 3 0 0 3 3 3 0 Nucleoporin Nup120/160 WD40_3 PF15911.5 ORZ00969.1 - 0.1 12.6 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Nbas_N PF15492.6 ORZ00969.1 - 0.12 11.7 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 ORZ00969.1 - 0.14 11.1 0.0 0.57 9.0 0.0 2.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 ORZ00970.1 - 1.1e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ00970.1 - 4.3e-32 111.4 0.0 6.5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORZ00970.1 - 0.00078 18.8 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORZ00970.1 - 0.0035 16.3 0.2 0.0066 15.4 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORZ00970.1 - 0.057 13.3 2.0 0.082 12.8 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Hc1 PF07432.13 ORZ00970.1 - 0.31 11.4 5.1 0.061 13.7 1.4 1.6 2 0 0 2 2 2 0 Histone H1-like protein Hc1 SAM_decarbox PF01536.16 ORZ00971.1 - 2.9e-125 418.0 0.0 3e-118 394.9 0.0 2.2 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase AMP-binding PF00501.28 ORZ00972.1 - 5.4e-71 239.4 0.4 7e-71 239.0 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ00972.1 - 2.6e-10 41.1 0.1 6.5e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RabGAP-TBC PF00566.18 ORZ00973.1 - 3.7e-38 131.3 0.4 9.4e-38 130.0 0.4 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.16 ORZ00974.1 - 4.5e-36 124.5 35.3 2.4e-29 102.4 18.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ00974.1 - 2.5e-19 69.5 13.5 7.9e-19 67.8 6.7 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORZ00974.1 - 1e-10 40.7 11.9 1.4e-10 40.3 11.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORZ00974.1 - 1.1e-05 24.1 1.5 1.1e-05 24.1 1.5 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector ELFV_dehydrog PF00208.21 ORZ00975.1 - 1.3e-56 192.1 0.0 2.3e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ORZ00975.1 - 5.9e-26 90.4 0.0 5.5e-18 64.0 0.0 2.4 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ORZ00975.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Nod1 PF17114.5 ORZ00975.1 - 0.53 10.4 4.9 0.87 9.7 0.2 2.9 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 PMT PF02366.18 ORZ00978.1 - 6.6e-77 258.4 16.2 6.6e-77 258.4 16.2 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORZ00978.1 - 1.5e-55 187.9 14.8 1.5e-55 187.9 14.8 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORZ00978.1 - 5.4e-37 127.5 0.4 9e-37 126.7 0.4 1.3 1 0 0 1 1 1 1 MIR domain Cullin_binding PF03556.15 ORZ00979.1 - 2.9e-32 111.6 2.3 2.9e-32 111.6 2.3 1.5 2 0 0 2 2 2 1 Cullin binding PTCB-BRCT PF12738.7 ORZ00980.1 - 9e-31 105.6 3.1 5.7e-12 45.4 0.0 5.9 7 0 0 7 7 7 4 twin BRCT domain BRCT PF00533.26 ORZ00980.1 - 5e-29 100.5 0.3 8.8e-07 29.2 0.0 6.0 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORZ00980.1 - 3.1e-17 62.8 0.1 0.046 14.1 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 ORZ00980.1 - 2.3e-12 46.7 0.0 9.7e-10 38.2 0.0 3.4 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 ORZ00980.1 - 3.5e-08 33.6 0.6 0.022 15.0 0.1 4.6 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain UCR_TM PF02921.14 ORZ00980.1 - 0.0068 16.9 0.4 0.0068 16.9 0.4 2.5 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region BRCT_3 PF18428.1 ORZ00980.1 - 0.03 14.4 0.3 4.8 7.3 0.0 3.4 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain PB1 PF00564.24 ORZ00981.1 - 0.0059 16.5 0.0 0.0094 15.9 0.0 1.3 1 1 0 1 1 1 1 PB1 domain Glycos_transf_3 PF00591.21 ORZ00982.1 - 1.8e-85 286.6 1.8 2.5e-85 286.1 1.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ORZ00982.1 - 2.2e-13 49.8 0.0 4.8e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain MIS13 PF08202.11 ORZ00983.1 - 8e-12 45.1 3.4 1.6e-11 44.1 3.4 1.5 1 1 0 1 1 1 1 Mis12-Mtw1 protein family RIH_assoc PF08454.11 ORZ00983.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 RyR and IP3R Homology associated PEX11 PF05648.14 ORZ00984.1 - 1.5e-28 99.8 0.0 1.7e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NAD_kinase PF01513.21 ORZ00985.1 - 4.1e-69 233.0 0.0 2.2e-68 230.6 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase Pyr_redox_2 PF07992.14 ORZ00986.1 - 8.5e-31 107.3 0.0 1.6e-28 99.8 0.0 1.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORZ00986.1 - 3.5e-15 56.3 0.5 1.9e-09 37.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 ORZ00986.1 - 3e-11 43.6 0.1 5.4e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.24 ORZ00986.1 - 1.1e-06 28.5 0.1 0.039 13.6 0.0 3.6 3 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORZ00986.1 - 3.7e-06 27.1 0.0 0.096 12.9 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORZ00986.1 - 9.5e-06 25.1 0.0 5.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RGS-like PF09128.11 ORZ00986.1 - 0.00024 20.9 0.1 0.00042 20.1 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain Lycopene_cycl PF05834.12 ORZ00986.1 - 0.0066 15.5 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 ORZ00986.1 - 0.0077 15.4 0.1 1 8.4 0.0 3.0 2 2 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORZ00986.1 - 0.022 14.7 1.0 34 4.4 0.2 3.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORZ00986.1 - 0.027 13.7 0.0 6 6.0 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain Fusion_gly PF00523.18 ORZ00986.1 - 0.032 12.5 0.3 0.046 12.0 0.3 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 ThiF PF00899.21 ORZ00986.1 - 0.057 12.8 0.0 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.14 ORZ00986.1 - 0.065 12.1 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Spermine_synth PF01564.17 ORZ00986.1 - 0.078 12.4 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Spermine/spermidine synthase domain GIDA PF01134.22 ORZ00986.1 - 0.098 11.7 0.0 2.2 7.3 0.0 3.0 4 0 0 4 4 4 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORZ00986.1 - 0.15 11.4 0.1 8.5 5.6 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain zf-CCCH PF00642.24 ORZ00987.1 - 4.4e-12 45.6 15.9 1.2e-06 28.2 3.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ORZ00987.1 - 2.2e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 ORZ00987.1 - 0.025 14.6 2.6 0.025 14.6 2.6 2.8 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 ORZ00987.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.7 2 1 0 2 2 2 0 Torus domain Asp PF00026.23 ORZ00988.1 - 3.9e-47 161.2 15.0 9.9e-26 90.9 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORZ00988.1 - 2e-06 28.1 10.0 1.1e-05 25.8 1.9 3.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORZ00988.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Dicty_REP PF05086.12 ORZ00988.1 - 0.6 8.0 4.3 0.72 7.7 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 ORZ00988.1 - 1.6 8.7 28.5 3.3 7.7 28.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein EKLF_TAD1 PF16832.5 ORZ00989.1 - 0.21 11.5 1.3 4.1 7.3 0.1 2.5 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 1 Maf1 PF09174.10 ORZ00990.1 - 8.7e-58 195.3 0.4 1.1e-57 195.0 0.4 1.1 1 0 0 1 1 1 1 Maf1 regulator zf-C2H2 PF00096.26 ORZ00992.1 - 5.8e-10 39.1 9.8 5e-05 23.5 2.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ00992.1 - 8e-07 29.2 0.8 8e-07 29.2 0.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ00992.1 - 0.058 13.4 0.2 0.058 13.4 0.2 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORZ00992.1 - 0.067 13.5 0.8 0.067 13.5 0.8 2.9 1 1 2 3 3 3 0 C2H2-type zinc ribbon ATG16 PF08614.11 ORZ00992.1 - 0.071 13.3 0.1 0.23 11.7 0.1 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-C2H2_aberr PF17017.5 ORZ00992.1 - 0.15 12.2 1.7 0.64 10.1 0.6 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ORZ00992.1 - 0.16 12.9 14.9 0.56 11.2 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1635 PF07795.11 ORZ00992.1 - 0.54 10.1 5.3 0.78 9.6 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) Macoilin PF09726.9 ORZ00992.1 - 1.7 7.1 4.1 2 6.9 4.1 1.1 1 0 0 1 1 1 0 Macoilin family Abhydrolase_6 PF12697.7 ORZ00993.1 - 0.011 16.3 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 ORZ00993.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1754 PF08555.10 ORZ00994.1 - 0.00012 22.8 27.8 0.0013 19.4 23.0 2.7 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) MAT1 PF06391.13 ORZ00994.1 - 0.33 10.8 14.2 0.4 10.5 14.2 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 STAC2_u1 PF16664.5 ORZ00994.1 - 0.49 10.8 5.4 0.58 10.6 5.4 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF2203 PF09969.9 ORZ00994.1 - 0.72 10.6 6.6 0.99 10.1 6.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FlpD PF02662.16 ORZ00994.1 - 0.78 9.7 3.4 1 9.4 2.7 1.5 1 1 1 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF3919 PF13057.6 ORZ00994.1 - 1.7 8.1 6.5 2.2 7.8 5.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3919) PWWP PF00855.17 ORZ00994.1 - 4.4 7.8 11.8 0.42 11.0 3.2 2.1 1 1 1 2 2 2 0 PWWP domain Ndc1_Nup PF09531.10 ORZ00994.1 - 9.7 4.7 6.0 11 4.6 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PPTA PF01239.22 ORZ00995.1 - 9.2e-37 123.7 16.9 4.1e-08 32.7 0.0 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 ORZ00995.1 - 0.00069 19.8 1.3 37 5.0 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ00995.1 - 0.034 15.0 0.2 3.3 8.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DMAP_binding PF06464.11 ORZ00996.1 - 3.3e-13 50.4 0.8 3.3e-13 50.4 0.8 3.0 3 1 0 3 3 3 1 DMAP1-binding Domain GvpG PF05120.12 ORZ00996.1 - 0.00015 21.7 1.1 0.00027 20.9 1.1 1.4 1 0 0 1 1 1 1 Gas vesicle protein G Mito_carr PF00153.27 ORZ00997.1 - 1.1e-66 220.8 2.5 5.4e-22 77.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 ORZ00997.1 - 0.038 14.4 3.9 0.79 10.1 0.4 2.6 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Peptidase_C97 PF05903.14 ORZ00998.1 - 1.2e-21 77.1 0.0 1.3e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 ORZ00998.1 - 0.017 15.5 0.1 0.02 15.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) LRAT PF04970.13 ORZ00998.1 - 0.018 15.4 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Lecithin retinol acyltransferase BTG PF07742.12 ORZ00998.1 - 0.03 14.2 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 BTG family Cullin PF00888.22 ORZ00999.1 - 1.3e-151 506.3 6.3 1.8e-151 505.9 6.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORZ00999.1 - 4.2e-24 84.4 4.8 4.2e-24 84.4 4.8 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 ORZ00999.1 - 0.029 14.9 0.7 0.21 12.1 0.4 2.7 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Penicillinase_R PF03965.16 ORZ00999.1 - 0.039 14.3 5.2 4 7.8 0.2 4.3 4 1 1 5 5 5 0 Penicillinase repressor GMP_synt_C PF00958.22 ORZ00999.1 - 0.25 11.4 1.4 1.9 8.6 0.4 2.7 3 0 0 3 3 3 0 GMP synthase C terminal domain ApbA_C PF08546.11 ORZ01000.1 - 4.4e-31 107.7 0.4 6.7e-31 107.1 0.4 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORZ01000.1 - 6.9e-25 87.5 0.0 9.9e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ORZ01000.1 - 9.5e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 ORZ01000.1 - 0.08 13.2 0.0 0.71 10.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 ORZ01000.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TIM PF00121.18 ORZ01001.1 - 1.8e-90 302.6 0.2 2e-90 302.4 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase RNA_pol_Rpa2_4 PF06883.12 ORZ01001.1 - 0.051 13.6 0.1 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase I, Rpa2 specific domain DUF2781 PF10914.8 ORZ01001.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Sugar_tr PF00083.24 ORZ01002.1 - 3.5e-49 167.9 16.9 4.5e-49 167.5 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ01002.1 - 4.4e-24 85.1 23.4 4.4e-24 85.1 23.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORZ01002.1 - 0.42 8.8 17.6 0.51 8.6 0.2 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UPF0016 PF01169.19 ORZ01003.1 - 6.4e-42 141.8 21.8 9.5e-21 73.9 6.7 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 ORZ01003.1 - 0.00019 21.3 3.1 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 1 Putative manganese efflux pump TauE PF01925.19 ORZ01003.1 - 0.00022 20.9 7.4 0.014 15.0 0.1 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE EF1_GNE PF00736.19 ORZ01003.1 - 0.075 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain DUF2407_C PF13373.6 ORZ01003.1 - 0.12 12.5 0.1 0.59 10.3 0.1 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF3494 PF11999.8 ORZ01003.1 - 0.15 11.7 1.6 0.23 11.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) Presenilin PF01080.17 ORZ01003.1 - 0.48 9.1 7.4 0.041 12.6 1.2 2.2 1 1 2 3 3 3 0 Presenilin DUF2070 PF09843.9 ORZ01003.1 - 0.58 8.4 7.2 0.082 11.2 0.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) TerC PF03741.16 ORZ01003.1 - 8.2 6.1 14.2 0.11 12.1 3.9 2.6 2 2 0 2 2 2 0 Integral membrane protein TerC family HSP20 PF00011.21 ORZ01004.1 - 6.8e-24 84.0 1.0 8.3e-24 83.7 1.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORZ01004.1 - 2.4e-09 36.6 0.0 3.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 ORZ01004.1 - 0.042 14.0 0.1 3.9 7.7 0.1 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal Complex1_LYR PF05347.15 ORZ01005.1 - 0.0023 17.9 0.1 0.004 17.2 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORZ01005.1 - 0.091 13.5 2.7 0.23 12.3 2.7 1.7 1 1 0 1 1 1 0 Complex1_LYR-like Amidase PF01425.21 ORZ01006.1 - 3.3e-123 412.0 0.1 4e-123 411.7 0.1 1.0 1 0 0 1 1 1 1 Amidase OPA3 PF07047.12 ORZ01007.1 - 3.2e-44 149.7 0.4 4.7e-44 149.2 0.2 1.4 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) YabA PF06156.13 ORZ01007.1 - 0.0021 18.7 1.2 0.0041 17.7 1.2 1.5 1 0 0 1 1 1 1 Initiation control protein YabA TSC22 PF01166.18 ORZ01007.1 - 0.012 15.9 2.5 0.024 14.9 2.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 ORZ01007.1 - 0.038 13.8 1.3 0.092 12.5 1.3 1.7 1 1 0 1 1 1 0 Septum formation initiator Fib_alpha PF08702.10 ORZ01007.1 - 0.16 12.2 1.4 0.33 11.1 1.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 ORZ01007.1 - 0.19 12.1 4.7 0.42 11.0 4.7 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C4H2 PF10146.9 ORZ01007.1 - 0.32 11.3 2.2 0.23 11.8 0.2 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein LPD5 PF18799.1 ORZ01007.1 - 0.76 10.2 3.6 0.82 10.1 2.4 1.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 bZIP_2 PF07716.15 ORZ01007.1 - 3.4 7.8 7.5 0.98 9.6 2.3 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF350 PF03994.14 ORZ01008.1 - 0.053 13.7 0.4 0.093 12.9 0.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) SHR3_chaperone PF08229.11 ORZ01008.1 - 0.059 12.4 0.1 0.061 12.3 0.1 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 S1FA PF04689.13 ORZ01009.1 - 0.052 13.7 0.4 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA DER1 PF04511.15 ORZ01009.1 - 0.069 13.1 0.3 0.087 12.7 0.3 1.2 1 0 0 1 1 1 0 Der1-like family ATP_transf PF09830.9 ORZ01010.1 - 1.4e-19 70.0 0.0 2.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 ORZ01010.1 - 3.2e-05 23.8 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) DUF4931 PF16285.5 ORZ01010.1 - 0.00041 19.7 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) HIT PF01230.23 ORZ01010.1 - 0.0033 18.1 0.1 0.014 16.1 0.0 2.0 2 1 0 2 2 2 1 HIT domain Acetyltransf_1 PF00583.25 ORZ01011.1 - 2e-16 60.3 0.2 2.5e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORZ01011.1 - 8.9e-10 38.9 0.0 1.4e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORZ01011.1 - 3.4e-08 33.5 0.0 5.5e-08 32.8 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORZ01011.1 - 0.00046 20.1 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORZ01011.1 - 0.014 16.1 0.0 0.021 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORZ01011.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CASP_C PF08172.12 ORZ01012.1 - 6.1e-67 225.6 0.1 6.1e-67 225.6 0.1 4.5 2 1 1 4 4 4 1 CASP C terminal DUF4407 PF14362.6 ORZ01012.1 - 0.0079 15.6 41.3 0.21 10.9 4.2 4.2 2 1 2 4 4 4 3 Domain of unknown function (DUF4407) HALZ PF02183.18 ORZ01012.1 - 0.13 12.5 0.2 0.13 12.5 0.2 7.0 5 3 3 8 8 8 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 ORZ01012.1 - 0.56 10.6 28.0 3.7 8.0 0.9 7.2 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) MAD PF05557.13 ORZ01012.1 - 7.5 4.8 65.9 0.036 12.4 40.3 3.6 4 0 0 4 4 4 0 Mitotic checkpoint protein MCM_bind PF09739.9 ORZ01013.1 - 7.4e-96 321.9 0.6 2.5e-89 300.3 0.2 2.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor RhoGAP PF00620.27 ORZ01014.1 - 3.1e-51 173.2 0.0 7.8e-51 171.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORZ01014.1 - 3e-17 62.6 27.8 1.6e-09 37.9 3.4 3.1 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 ORZ01014.1 - 3.2e-07 30.1 4.4 3.2e-07 30.1 4.4 4.3 2 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 ORZ01014.1 - 0.0018 18.6 0.8 0.0018 18.6 0.8 4.2 3 2 1 4 4 4 1 C1 domain UPF0515 PF15135.6 ORZ01014.1 - 0.011 15.1 0.8 0.011 15.1 0.8 3.1 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Fez1 PF06818.15 ORZ01014.1 - 0.048 14.1 22.1 0.59 10.6 10.2 3.3 3 0 0 3 3 3 0 Fez1 Laminin_II PF06009.12 ORZ01014.1 - 0.22 11.5 12.5 0.014 15.4 4.4 2.8 3 0 0 3 3 3 0 Laminin Domain II RICH PF05062.12 ORZ01014.1 - 0.31 11.4 8.5 6.7 7.1 0.1 3.7 2 1 2 4 4 4 0 RICH domain HALZ PF02183.18 ORZ01014.1 - 1 9.7 8.0 1.1 9.6 0.6 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 ORZ01014.1 - 1.3 9.3 24.7 0.056 13.7 5.6 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.32 ORZ01015.1 - 5.2e-15 55.6 6.6 0.025 15.4 0.2 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01015.1 - 2.3e-09 37.4 0.0 0.0044 17.3 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ01015.1 - 0.0015 17.9 0.1 0.0056 16.1 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain RR_TM4-6 PF06459.12 ORZ01015.1 - 0.0036 17.2 3.1 0.0052 16.7 3.1 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DAGK_cat PF00781.24 ORZ01015.1 - 0.01 15.5 0.0 0.94 9.1 0.0 2.5 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain YL1 PF05764.13 ORZ01015.1 - 0.014 15.6 17.8 0.021 15.0 17.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PQQ_2 PF13360.6 ORZ01015.1 - 0.018 14.6 0.0 0.14 11.7 0.0 2.2 2 1 0 2 2 2 0 PQQ-like domain Nop14 PF04147.12 ORZ01015.1 - 0.11 10.7 13.3 0.14 10.3 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family TSGP1 PF07771.11 ORZ01015.1 - 0.43 10.8 10.9 1.1 9.4 10.9 1.7 1 0 0 1 1 1 0 Tick salivary peptide group 1 CDC45 PF02724.14 ORZ01015.1 - 0.73 8.0 15.5 1.1 7.4 15.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 ORZ01015.1 - 0.8 8.6 4.3 1.1 8.1 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 ORZ01015.1 - 1.3 9.4 6.4 2.4 8.6 6.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2457 PF10446.9 ORZ01015.1 - 3.1 6.8 22.3 0.33 10.1 18.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.12 ORZ01015.1 - 4.7 5.7 24.1 6.5 5.2 24.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 ORZ01015.1 - 6.9 4.6 20.5 9.8 4.1 20.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 ORZ01016.1 - 7.7e-45 153.3 51.7 5.1e-38 130.9 18.1 3.2 3 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 ORZ01016.1 - 2.3e-14 52.7 18.6 2.3e-14 52.7 18.6 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORZ01016.1 - 2.5e-14 53.0 8.0 2.5e-14 53.0 8.0 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter DUF5345 PF17280.2 ORZ01016.1 - 0.0077 16.2 0.1 8.8 6.4 0.0 3.2 2 0 0 2 2 2 2 Family of unknown function (DUF5345) CRM1_repeat_3 PF18787.1 ORZ01016.1 - 0.075 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 Mpv17_PMP22 PF04117.12 ORZ01016.1 - 0.15 12.3 1.3 0.91 9.8 0.2 2.8 3 0 0 3 3 3 0 Mpv17 / PMP22 family ORC4_C PF14629.6 ORZ01017.1 - 5.5e-48 163.2 0.0 9.1e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 ORZ01017.1 - 6e-18 65.8 0.3 1.3e-17 64.7 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ORZ01017.1 - 3.2e-09 37.3 0.0 8.6e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORZ01017.1 - 2.1e-08 34.5 0.0 3.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORZ01017.1 - 2.4e-06 27.6 0.1 6.4e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.13 ORZ01017.1 - 4.4e-06 26.0 0.0 7.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORZ01017.1 - 0.00032 20.3 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region KAP_NTPase PF07693.14 ORZ01017.1 - 0.00077 18.8 0.1 0.017 14.4 0.0 2.6 2 1 0 3 3 3 1 KAP family P-loop domain ATPase_2 PF01637.18 ORZ01017.1 - 0.00094 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ORZ01017.1 - 0.0023 18.3 0.0 0.0054 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORZ01017.1 - 0.0027 17.7 0.0 0.043 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF3445 PF11927.8 ORZ01017.1 - 0.0037 16.9 1.0 0.024 14.3 0.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) DAP3 PF10236.9 ORZ01017.1 - 0.011 14.9 0.1 1.5 7.9 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 ORZ01017.1 - 0.016 14.6 0.0 0.066 12.6 0.0 1.9 1 1 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 ORZ01017.1 - 0.033 13.9 0.0 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 ORZ01017.1 - 0.037 13.2 0.0 0.13 11.4 0.0 1.8 1 1 1 2 2 2 0 PIF1-like helicase Bac_DnaA PF00308.18 ORZ01017.1 - 0.047 13.5 0.5 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial dnaA protein TrwB_AAD_bind PF10412.9 ORZ01017.1 - 0.051 12.5 0.5 3.1 6.6 0.1 2.6 1 1 2 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 ORZ01017.1 - 0.06 13.5 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORZ01017.1 - 0.088 13.2 0.0 0.67 10.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 ORZ01017.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORZ01017.1 - 0.13 12.0 0.5 0.33 10.7 0.5 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 ORZ01017.1 - 0.17 11.9 0.6 2.1 8.4 0.1 3.0 3 1 0 3 3 3 0 AAA domain Abhydrolase_3 PF07859.13 ORZ01018.1 - 2.7e-36 125.4 0.0 3.6e-25 89.1 0.0 3.4 3 1 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORZ01018.1 - 0.00077 18.4 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase CCDC106 PF15794.5 ORZ01018.1 - 0.077 12.7 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Yae1_N PF09811.9 ORZ01019.1 - 4.1e-10 39.2 4.0 5.1e-10 38.9 4.0 1.1 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Complex1_LYR PF05347.15 ORZ01020.1 - 8.8e-19 67.3 1.0 8.8e-19 67.3 1.0 1.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORZ01020.1 - 0.00025 21.7 1.3 0.00027 21.6 1.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF2937 PF11157.8 ORZ01020.1 - 0.0092 15.7 0.2 0.01 15.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Complex1_LYR_1 PF13232.6 ORZ01020.1 - 0.013 16.1 0.3 0.016 15.8 0.3 1.2 1 1 0 1 1 1 0 Complex1_LYR-like DUF5358 PF17311.2 ORZ01020.1 - 0.033 14.2 0.1 0.04 13.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5358) Bap31_Bap29_C PF18035.1 ORZ01020.1 - 0.085 12.9 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain G_path_suppress PF15991.5 ORZ01021.1 - 0.65 10.1 23.9 0.021 15.0 16.2 2.3 1 1 1 2 2 2 0 G-protein pathway suppressor Methyltransf_11 PF08241.12 ORZ01022.1 - 1.4e-15 57.7 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ01022.1 - 7.7e-15 55.4 0.0 1.6e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ01022.1 - 7.8e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ01022.1 - 2.6e-11 43.6 0.0 4.7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ01022.1 - 1.3e-07 31.2 0.0 4.9e-06 26.1 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORZ01022.1 - 6.2e-06 25.8 0.0 8.7e-05 22.1 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 ORZ01022.1 - 2.9e-05 24.7 0.0 4.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ01022.1 - 0.00027 20.5 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORZ01022.1 - 0.00076 18.8 0.0 0.0014 17.9 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase domain TehB PF03848.14 ORZ01022.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 ORZ01022.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 ORZ01022.1 - 0.023 14.7 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 ORZ01022.1 - 0.042 13.7 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF938 PF06080.12 ORZ01022.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Glycos_transf_1 PF00534.20 ORZ01024.1 - 9.4e-13 48.1 0.0 1.9e-12 47.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORZ01024.1 - 1.1e-11 45.2 0.0 6.4e-11 42.8 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORZ01024.1 - 1.2e-07 32.3 1.3 1.9e-07 31.6 0.4 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ORZ01024.1 - 2e-06 28.1 0.0 4.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORZ01024.1 - 6.5e-05 23.0 1.5 0.00012 22.2 1.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF884 PF05959.11 ORZ01024.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Pkinase PF00069.25 ORZ01025.1 - 1.1e-49 169.2 0.0 1.5e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01025.1 - 6.3e-35 120.7 0.0 8.3e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ01025.1 - 9e-05 21.4 0.0 0.00019 20.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORZ01025.1 - 0.0032 16.8 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 ORZ01025.1 - 0.25 10.3 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RRM_1 PF00076.22 ORZ01027.1 - 1.7e-20 72.6 3.5 1.1e-09 37.9 0.0 3.8 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ01027.1 - 9.6e-08 32.0 1.5 0.024 14.7 0.8 3.0 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 ORZ01027.1 - 6.6e-05 22.8 1.6 0.12 12.2 0.1 3.1 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 ORZ01027.1 - 0.042 13.7 0.1 2.2 8.2 0.0 2.6 2 1 0 2 2 2 0 Occluded RNA-recognition motif TMPIT PF07851.13 ORZ01027.1 - 0.24 10.6 6.7 0.3 10.3 6.1 1.4 1 1 0 1 1 1 0 TMPIT-like protein Presenilin PF01080.17 ORZ01027.1 - 3.9 6.1 6.9 5.9 5.5 6.9 1.3 1 0 0 1 1 1 0 Presenilin Zn_clus PF00172.18 ORZ01028.1 - 5.2e-05 23.3 6.3 0.00014 21.9 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PADR1 PF08063.12 ORZ01028.1 - 0.039 13.7 1.1 0.093 12.5 1.1 1.6 1 0 0 1 1 1 0 PADR1 (NUC008) domain Adap_comp_sub PF00928.21 ORZ01029.1 - 2.5e-25 89.4 0.0 4.1e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORZ01029.1 - 2.2e-07 30.9 0.4 3.9e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MBR1 PF17058.5 ORZ01029.1 - 0.0043 17.4 0.5 0.0067 16.7 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis regulation protein 1 Lin-8 PF03353.15 ORZ01029.1 - 0.019 14.5 1.3 0.03 13.9 1.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RPM2 PF08579.11 ORZ01029.1 - 0.031 14.7 0.2 0.061 13.7 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4337 PF14235.6 ORZ01029.1 - 0.068 13.3 4.2 0.11 12.6 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2326 PF10088.9 ORZ01029.1 - 0.09 12.5 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Chitin_synth_2 PF03142.15 ORZ01030.1 - 4.1e-270 896.9 1.9 5.7e-270 896.4 1.9 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORZ01030.1 - 2.4e-10 40.7 0.0 2.7e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORZ01030.1 - 3e-07 30.6 11.5 2e-06 27.9 11.5 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 ORZ01030.1 - 1.9e-05 24.7 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORZ01030.1 - 0.0051 16.6 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORZ01030.1 - 0.0068 15.9 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_transf_20 PF00982.21 ORZ01031.1 - 1.9e-165 551.1 0.0 2.4e-165 550.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORZ01031.1 - 5.8e-78 261.2 0.0 1.8e-76 256.4 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORZ01031.1 - 0.00071 19.4 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase COPI_assoc PF08507.10 ORZ01032.1 - 1.4e-20 73.7 10.7 2.8e-15 56.5 6.6 2.1 2 0 0 2 2 2 2 COPI associated protein CrgA PF06781.12 ORZ01032.1 - 0.54 10.4 3.4 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF2583 PF10762.9 ORZ01032.1 - 1.6 9.2 4.0 4.5 7.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) DUF3096 PF11295.8 ORZ01032.1 - 5.1 6.8 9.4 0.24 11.1 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) Ras PF00071.22 ORZ01033.1 - 5.5e-63 211.4 0.2 6.7e-63 211.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ01033.1 - 6.9e-36 123.1 0.2 1e-35 122.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ01033.1 - 1.7e-13 50.4 0.1 2.3e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORZ01033.1 - 7.9e-07 29.2 0.1 1.4e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORZ01033.1 - 0.00011 22.1 0.1 0.036 14.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORZ01033.1 - 0.00023 20.8 0.3 0.0011 18.6 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORZ01033.1 - 0.00023 21.4 0.0 0.0016 18.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 ORZ01033.1 - 0.00076 18.9 0.0 0.0011 18.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORZ01033.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DLIC PF05783.11 ORZ01033.1 - 0.0035 16.2 0.0 0.047 12.5 0.1 2.0 1 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 ORZ01033.1 - 0.006 17.0 0.1 0.011 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 ORZ01033.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 ORZ01033.1 - 0.022 14.2 0.0 0.074 12.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 ORZ01033.1 - 0.031 14.3 0.1 0.079 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 ORZ01033.1 - 0.032 13.8 0.2 0.061 12.9 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 ORZ01033.1 - 0.032 14.0 0.0 0.075 12.8 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORZ01033.1 - 0.042 14.4 0.1 0.057 13.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 ORZ01033.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FAD-SLDH PF12318.8 ORZ01033.1 - 0.074 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_28 PF13521.6 ORZ01033.1 - 0.083 13.1 0.1 0.58 10.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 ORZ01033.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SpoIIID PF12116.8 ORZ01033.1 - 0.11 12.6 0.1 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Stage III sporulation protein D NACHT PF05729.12 ORZ01033.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Pex24p PF06398.11 ORZ01034.1 - 6.3e-15 55.0 11.7 9.2e-15 54.5 11.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Mcp5_PH PF12814.7 ORZ01035.1 - 2.3e-07 30.9 3.8 1.1e-06 28.7 3.8 2.1 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Wtap PF17098.5 ORZ01035.1 - 0.00077 19.4 18.5 0.049 13.6 11.0 2.3 1 1 1 2 2 2 2 WTAP/Mum2p family Fez1 PF06818.15 ORZ01035.1 - 0.12 12.8 16.2 0.26 11.7 16.2 1.6 1 0 0 1 1 1 0 Fez1 GAS PF13851.6 ORZ01035.1 - 0.29 10.4 19.6 1.5 8.1 13.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMCO5 PF14992.6 ORZ01035.1 - 0.38 10.3 13.3 0.76 9.3 13.4 1.4 1 1 0 1 1 1 0 TMCO5 family PPP4R2 PF09184.11 ORZ01035.1 - 1.3 8.6 11.0 2 8.0 11.0 1.2 1 0 0 1 1 1 0 PPP4R2 ERM PF00769.19 ORZ01035.1 - 1.9 8.2 22.5 7.4 6.3 22.5 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ATG16 PF08614.11 ORZ01035.1 - 2.3 8.4 26.7 0.31 11.3 8.2 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) USP7_ICP0_bdg PF12436.8 ORZ01036.1 - 2.7e-74 249.5 0.1 2.1e-73 246.6 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 ORZ01036.1 - 4.5e-57 193.1 4.2 4.8e-54 183.2 0.6 3.7 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 ORZ01036.1 - 6e-50 170.1 0.3 1.1e-49 169.3 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORZ01036.1 - 4.8e-24 85.5 0.0 7.6e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORZ01036.1 - 5.1e-07 29.8 0.0 2.2e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 MATH domain Lipase_3 PF01764.25 ORZ01037.1 - 4.9e-18 65.4 0.0 8.3e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 ORZ01037.1 - 0.077 12.7 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ORZ01037.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family C2 PF00168.30 ORZ01038.1 - 0.00012 22.4 0.0 0.00012 22.3 0.0 1.1 1 0 0 1 1 1 1 C2 domain RraA-like PF03737.15 ORZ01039.1 - 4.1e-35 121.2 0.0 5.3e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Myb_DNA-bind_6 PF13921.6 ORZ01040.1 - 3e-05 24.2 0.0 3.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORZ01040.1 - 0.00017 21.7 0.0 0.00022 21.4 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Methyltransf_1N PF02870.15 ORZ01041.1 - 0.078 13.8 0.0 0.095 13.5 0.0 1.2 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain TruD PF01142.18 ORZ01042.1 - 3.1e-60 204.1 0.0 1e-55 189.3 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Med20 PF08612.11 ORZ01043.1 - 6.2e-30 104.2 0.2 7.3e-30 104.0 0.2 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FabA PF07977.13 ORZ01043.1 - 0.035 13.7 0.1 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 FabA-like domain Glyco_hydro_63N PF16923.5 ORZ01043.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain GPI-anchored PF10342.9 ORZ01044.1 - 1.1e-15 58.1 0.7 1.1e-15 58.1 0.7 2.4 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CopC PF04234.12 ORZ01044.1 - 0.17 12.9 0.1 0.17 12.9 0.1 2.2 2 1 0 2 2 2 0 CopC domain Big_3_4 PF13754.6 ORZ01044.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function SOG2 PF10428.9 ORZ01044.1 - 0.24 10.5 15.9 0.27 10.4 15.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GLEYA PF10528.9 ORZ01044.1 - 2.7 8.5 4.7 1.1 9.7 0.4 2.4 2 1 1 3 3 3 0 GLEYA domain zf-C2H2 PF00096.26 ORZ01045.1 - 1.7e-12 47.1 8.3 1.1e-06 28.8 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ01045.1 - 1.7e-10 40.8 6.9 9e-05 23.0 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORZ01045.1 - 2.4e-07 30.9 17.9 3.6e-07 30.3 1.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ01045.1 - 1e-05 25.4 4.4 0.007 16.3 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORZ01045.1 - 0.0011 19.3 4.3 0.36 11.3 1.0 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORZ01045.1 - 0.0015 18.4 4.9 0.0026 17.6 0.2 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 ORZ01045.1 - 0.0042 17.3 10.6 0.035 14.4 0.1 2.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORZ01045.1 - 0.016 15.7 2.5 0.34 11.4 0.0 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 ORZ01045.1 - 0.045 13.5 1.4 0.045 13.5 1.4 3.3 3 1 0 3 3 3 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 ORZ01045.1 - 0.065 13.9 0.2 0.097 13.3 0.2 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain Tox-GHH PF15636.6 ORZ01046.1 - 0.036 14.0 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin PHO4 PF01384.20 ORZ01047.1 - 2.1e-122 408.4 12.0 2.4e-122 408.2 12.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family CDC45 PF02724.14 ORZ01047.1 - 0.068 11.5 3.7 0.095 11.0 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1240 PF06836.12 ORZ01047.1 - 0.14 12.7 1.2 0.25 11.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) TP_methylase PF00590.20 ORZ01048.1 - 1.3e-44 152.7 0.1 2.2e-44 151.9 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ORZ01048.1 - 6.3e-29 100.5 0.1 1.9e-28 99.0 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORZ01048.1 - 3.6e-16 58.5 2.0 1.1e-15 57.0 1.5 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORZ01048.1 - 2.5e-13 49.2 0.4 1.9e-12 46.4 0.1 2.3 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central ThiF PF00899.21 ORZ01048.1 - 0.0013 18.2 0.0 0.0039 16.6 0.0 2.1 2 1 0 2 2 2 1 ThiF family Pyr_redox_3 PF13738.6 ORZ01048.1 - 0.0027 17.0 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORZ01048.1 - 0.017 14.4 0.7 0.057 12.7 0.4 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ORZ01048.1 - 0.12 12.4 0.2 0.44 10.6 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CH PF00307.31 ORZ01049.1 - 4.3e-33 113.7 0.0 1e-15 57.9 0.0 3.5 2 0 0 2 2 2 2 Calponin homology (CH) domain GAS2 PF02187.17 ORZ01049.1 - 4.3e-11 42.7 0.1 1.6e-10 40.9 0.1 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.8 ORZ01049.1 - 0.0047 16.7 0.0 0.21 11.4 0.0 3.0 2 0 0 2 2 2 1 CAMSAP CH domain DUF3685 PF12452.8 ORZ01049.1 - 0.084 12.6 2.1 4.1 7.1 0.3 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3685) RVT_3 PF13456.6 ORZ01049.1 - 3.9 7.3 6.7 2.2 8.1 0.5 3.6 3 0 0 3 3 3 0 Reverse transcriptase-like LAG1-DNAbind PF09271.11 ORZ01050.1 - 1.1e-48 165.7 0.0 1.1e-48 165.7 0.0 2.6 3 1 0 3 3 3 1 LAG1, DNA binding BTD PF09270.10 ORZ01050.1 - 7.5e-23 81.4 0.0 3.5e-21 76.0 0.0 3.0 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain TMEM171 PF15471.6 ORZ01050.1 - 0.0084 15.1 0.7 0.0084 15.1 0.7 2.2 2 0 0 2 2 2 1 Transmembrane protein family 171 C12orf66_like PF09404.10 ORZ01051.1 - 6.8e-39 133.9 0.0 6.1e-38 130.8 0.0 2.0 1 1 0 1 1 1 1 KICSTOR complex C12orf66 like EMP24_GP25L PF01105.24 ORZ01052.1 - 1.4e-54 184.8 0.1 1.6e-54 184.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cytochrom_C PF00034.21 ORZ01053.1 - 1.6e-11 45.2 0.0 2.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORZ01053.1 - 6e-08 32.9 2.9 2.8e-07 30.8 2.9 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORZ01053.1 - 0.00029 20.5 0.2 0.006 16.3 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 ORZ01053.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 RNA_bind PF08675.11 ORZ01054.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain DUF4211 PF13926.6 ORZ01056.1 - 8.5e-16 58.3 0.1 8.6e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) TFIIA PF03153.13 ORZ01056.1 - 0.077 13.0 11.3 0.11 12.5 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF448 PF04296.13 ORZ01056.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) Sel1 PF08238.12 ORZ01057.1 - 2.6e-121 393.3 138.4 3.7e-07 30.6 0.3 33.5 33 2 1 34 34 34 28 Sel1 repeat FHA PF00498.26 ORZ01058.1 - 5e-14 52.4 0.2 1.6e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 FHA domain THRAP3_BCLAF1 PF15440.6 ORZ01058.1 - 0.0085 15.2 15.3 0.0092 15.1 15.3 1.1 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Yop-YscD_cpl PF16697.5 ORZ01058.1 - 0.0098 16.2 0.1 0.62 10.4 0.1 2.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF5024 PF16427.5 ORZ01058.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) Pro_isomerase PF00160.21 ORZ01059.1 - 6.5e-54 182.5 0.0 7.2e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 ORZ01059.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) PALP PF00291.25 ORZ01060.1 - 2.7e-62 210.8 0.1 3.8e-62 210.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme pPIWI_RE_REase PF18154.1 ORZ01060.1 - 0.004 17.1 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 REase associating with pPIWI_RE DUF3042 PF11240.8 ORZ01060.1 - 0.028 14.4 0.4 0.11 12.6 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Pkinase PF00069.25 ORZ01061.1 - 1.3e-09 37.8 0.0 2.5e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 ORZ01061.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Abhydrolase_6 PF12697.7 ORZ01062.1 - 1.2e-08 35.8 0.0 1.5e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORZ01062.1 - 0.00015 21.1 0.0 0.00037 19.8 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORZ01063.1 - 3.4e-08 34.4 0.0 4.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORZ01063.1 - 3.2e-06 26.6 0.0 1.2e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORZ01065.1 - 1.7e-08 35.3 0.0 2.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORZ01065.1 - 3.3e-05 23.3 0.0 9.7e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORZ01065.1 - 0.024 14.3 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold zf-HIT PF04438.16 ORZ01066.1 - 1.2e-10 41.1 11.8 1.8e-10 40.5 11.8 1.3 1 0 0 1 1 1 1 HIT zinc finger HMG_box PF00505.19 ORZ01066.1 - 0.064 13.7 0.1 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box zf-MYND PF01753.18 ORZ01066.1 - 0.41 10.8 8.0 0.23 11.6 6.0 1.6 1 1 0 1 1 1 0 MYND finger zf-C2H2_3 PF13878.6 ORZ01066.1 - 0.5 10.2 5.7 1.3 8.9 5.7 1.7 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO RRM_1 PF00076.22 ORZ01067.1 - 2.6e-06 27.1 0.0 3.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transket_pyr PF02779.24 ORZ01068.1 - 5.2e-48 163.1 0.0 9.2e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORZ01068.1 - 6.1e-41 139.2 0.1 1.5e-40 137.9 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ORZ01068.1 - 0.0025 18.1 0.0 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Metallophos PF00149.28 ORZ01069.1 - 6.7e-38 131.2 0.1 1e-37 130.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORZ01069.1 - 4.5e-16 59.0 0.1 9.4e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metaviral_G PF09595.10 ORZ01069.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 Metaviral_G glycoprotein MutS_I PF01624.20 ORZ01069.1 - 0.19 11.9 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 MutS domain I MAGI_u5 PF16666.5 ORZ01069.1 - 0.93 9.6 7.3 1.6 8.9 7.3 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI EamA PF00892.20 ORZ01070.1 - 5.3e-05 23.4 12.7 0.00014 22.0 12.7 1.6 1 1 0 1 1 1 1 EamA-like transporter family UAA PF08449.11 ORZ01070.1 - 0.025 13.8 1.1 0.035 13.3 1.0 1.2 1 1 0 1 1 1 0 UAA transporter family TMEM234 PF10639.9 ORZ01070.1 - 0.032 14.2 2.4 0.033 14.2 0.9 1.7 1 1 1 2 2 2 0 Putative transmembrane family 234 CLU PF13236.6 ORZ01071.1 - 2.4e-82 276.0 0.0 6.5e-82 274.6 0.0 1.8 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 ORZ01071.1 - 5.6e-50 169.8 2.3 8.7e-50 169.2 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 ORZ01071.1 - 3.5e-23 81.7 7.5 7.7e-10 38.9 1.6 4.1 2 2 2 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 ORZ01071.1 - 1.8e-21 76.3 0.0 2.1e-20 72.8 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 ORZ01071.1 - 5.5e-19 67.4 1.5 7.5e-06 25.6 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat DUF727 PF05303.12 ORZ01071.1 - 4.6e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_1 PF00515.28 ORZ01071.1 - 0.01 15.6 10.6 0.49 10.3 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ01071.1 - 0.12 12.5 16.1 1.3 9.3 0.2 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ01071.1 - 0.17 12.2 1.5 2.3 8.5 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORZ01071.1 - 0.35 11.2 9.5 7.7 7.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ01071.1 - 0.59 10.3 6.7 6.4 7.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SET PF00856.28 ORZ01071.1 - 4.2 7.7 5.9 3 8.2 1.3 2.5 1 1 0 2 2 2 0 SET domain PI3_PI4_kinase PF00454.27 ORZ01074.1 - 3.6e-56 190.8 0.0 9e-56 189.5 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 ORZ01074.1 - 4.4e-55 187.2 0.0 1.1e-54 185.8 0.0 1.7 1 0 0 1 1 1 1 NUC194 domain FAT PF02259.23 ORZ01074.1 - 1e-13 51.3 7.3 2.1e-13 50.2 6.4 2.0 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 ORZ01074.1 - 8.9e-10 38.2 0.2 2.2e-09 36.9 0.2 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 ORZ01074.1 - 0.02 15.1 7.1 22 5.6 0.2 6.2 6 0 0 6 6 6 0 HEAT repeat E1-E2_ATPase PF00122.20 ORZ01075.1 - 2e-51 174.1 0.6 1.8e-50 171.0 0.2 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 ORZ01075.1 - 1.2e-14 53.7 0.1 2.6e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 ORZ01075.1 - 1.3e-05 25.6 0.3 0.0001 22.7 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORZ01075.1 - 0.0034 17.4 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Holin_BlyA PF05102.12 ORZ01075.1 - 0.1 12.6 0.3 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 holin, BlyA family DUF2244 PF10003.9 ORZ01075.1 - 0.14 11.8 0.5 0.34 10.6 0.3 1.7 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) Q_salvage PF10343.9 ORZ01076.1 - 1.3e-119 399.0 0.0 1.7e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ORC3_N PF07034.11 ORZ01077.1 - 1.6e-65 221.4 0.6 1.6e-65 221.4 0.6 2.2 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 ORZ01077.1 - 9.6e-33 113.2 1.4 1e-17 64.5 0.0 3.3 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal CNOT11 PF10155.9 ORZ01078.1 - 1.6e-28 99.4 0.2 3.1e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 zf-Tim10_DDP PF02953.15 ORZ01079.1 - 1.7e-25 88.5 0.1 2.1e-25 88.2 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MRG PF05712.13 ORZ01080.1 - 7.1e-47 159.3 0.6 1.2e-46 158.5 0.6 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 ORZ01080.1 - 2.2e-08 33.9 1.8 5.3e-08 32.6 1.8 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 ORZ01080.1 - 0.037 13.9 3.6 0.096 12.6 3.6 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Palm_thioest PF02089.15 ORZ01084.1 - 3e-81 272.8 0.0 3.6e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 ORZ01084.1 - 0.086 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 ORZ01084.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold zinc_ribbon_16 PF17034.5 ORZ01084.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family 5_nucleotid_C PF02872.18 ORZ01086.1 - 0.0082 16.4 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain B12-binding PF02310.19 ORZ01086.1 - 0.0096 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain bZIP_1 PF00170.21 ORZ01087.1 - 1.1e-08 35.0 9.7 2.1e-08 34.1 9.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORZ01087.1 - 1.4e-05 25.1 10.4 2.6e-05 24.2 10.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper NAM-associated PF14303.6 ORZ01087.1 - 0.0026 18.5 6.9 0.0047 17.7 6.9 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain bZIP_Maf PF03131.17 ORZ01087.1 - 0.0029 18.1 5.5 0.009 16.5 5.5 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4711 PF15829.5 ORZ01087.1 - 0.099 12.6 2.4 0.17 11.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) DivIC PF04977.15 ORZ01087.1 - 0.18 11.6 1.8 0.38 10.6 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Forkhead PF00250.18 ORZ01088.1 - 1.1e-31 108.9 0.0 3.1e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 Forkhead domain SMYLE_N PF18615.1 ORZ01088.1 - 0.43 10.1 0.0 0.43 10.1 0.0 2.5 3 0 0 3 3 3 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Nop14 PF04147.12 ORZ01089.1 - 6.7e-283 941.1 48.0 7.8e-283 940.9 48.0 1.0 1 0 0 1 1 1 1 Nop14-like family SpoU_methylase PF00588.19 ORZ01090.1 - 5.4e-30 104.4 0.0 9.7e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ORZ01090.1 - 1.1e-07 32.0 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding MMtag PF10159.9 ORZ01090.1 - 0.19 12.0 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Multiple myeloma tumor-associated SHMT PF00464.19 ORZ01092.1 - 6.6e-180 597.9 0.0 7.8e-180 597.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 ORZ01092.1 - 1e-05 25.0 0.0 6.1e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORZ01092.1 - 9.5e-05 21.7 0.0 0.0002 20.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DUF4142 PF13628.6 ORZ01092.1 - 0.056 13.7 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) DegT_DnrJ_EryC1 PF01041.17 ORZ01092.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OHA PF14418.6 ORZ01092.1 - 0.11 12.3 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 OST-HTH Associated domain ABC_membrane PF00664.23 ORZ01093.1 - 6.7e-88 294.9 30.2 1.1e-44 153.1 14.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORZ01093.1 - 4.1e-51 173.1 0.8 9e-27 94.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter MTABC_N PF16185.5 ORZ01093.1 - 1.5e-11 44.3 3.5 5.2e-11 42.5 3.5 1.9 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 ORZ01093.1 - 2.1e-10 40.4 0.1 0.00053 19.5 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORZ01093.1 - 5.2e-05 23.3 2.5 0.077 13.1 0.3 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORZ01093.1 - 5.6e-05 23.6 0.5 0.39 11.1 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORZ01093.1 - 0.00015 21.4 0.4 0.13 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORZ01093.1 - 0.00096 19.1 0.5 0.13 12.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase CDC45 PF02724.14 ORZ01093.1 - 0.0014 17.1 0.2 0.0036 15.7 0.0 1.7 2 0 0 2 2 2 1 CDC45-like protein DUF87 PF01935.17 ORZ01093.1 - 0.01 15.9 8.0 0.35 10.9 0.6 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_25 PF13481.6 ORZ01093.1 - 0.017 14.7 0.1 0.15 11.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 ORZ01093.1 - 0.028 13.4 1.9 10 4.9 0.1 3.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain FANCI_HD2 PF14680.6 ORZ01093.1 - 0.049 12.9 0.2 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 FANCI helical domain 2 Roc PF08477.13 ORZ01093.1 - 0.086 13.1 0.0 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORZ01093.1 - 0.38 11.0 3.7 12 6.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ORZ01093.1 - 0.46 10.5 5.3 0.51 10.4 0.7 2.6 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.6 ORZ01093.1 - 1.9 8.2 4.7 19 5.0 0.1 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system adh_short PF00106.25 ORZ01094.1 - 7.4e-43 146.3 0.0 1.2e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ01094.1 - 9.1e-33 113.8 0.1 1.2e-32 113.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORZ01094.1 - 3.2e-10 40.2 0.0 4.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 ORZ01094.1 - 0.0047 16.3 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ORZ01094.1 - 0.0057 16.1 0.2 0.017 14.6 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABC_membrane PF00664.23 ORZ01095.1 - 1.3e-105 352.9 24.2 3.2e-57 194.3 13.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORZ01095.1 - 1.1e-69 233.3 0.1 5.8e-35 120.8 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 ORZ01095.1 - 3.8e-14 52.7 6.8 8.6e-07 28.6 0.1 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORZ01095.1 - 5.7e-09 36.4 0.2 0.0013 19.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORZ01095.1 - 1.1e-08 35.7 2.9 0.0005 20.5 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ORZ01095.1 - 2e-07 30.9 1.5 0.0019 18.0 0.2 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORZ01095.1 - 1.1e-06 28.2 0.6 0.063 13.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORZ01095.1 - 1.9e-06 27.0 3.0 0.0029 16.5 0.2 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ORZ01095.1 - 7.3e-06 26.0 0.1 0.043 13.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 ORZ01095.1 - 4.1e-05 23.8 0.0 0.31 11.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORZ01095.1 - 7.9e-05 22.0 0.2 0.033 13.5 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Rad17 PF03215.15 ORZ01095.1 - 9e-05 22.5 0.0 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 ORZ01095.1 - 0.00026 20.8 0.0 0.028 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 ORZ01095.1 - 0.0003 20.9 4.0 0.44 10.8 0.5 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ORZ01095.1 - 0.00036 21.1 7.8 0.93 10.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 ORZ01095.1 - 0.00043 19.6 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 ORZ01095.1 - 0.00044 20.7 9.2 0.98 9.8 0.3 4.5 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORZ01095.1 - 0.00061 19.3 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 ORZ01095.1 - 0.00064 19.6 0.2 13 5.5 0.0 4.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Cytidylate_kin PF02224.18 ORZ01095.1 - 0.001 18.8 0.0 0.9 9.2 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase AAA_5 PF07728.14 ORZ01095.1 - 0.0036 17.3 0.3 2.6 8.0 0.0 3.2 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORZ01095.1 - 0.004 17.4 0.1 2.4 8.4 0.1 3.2 2 1 1 3 3 3 1 AAA domain APS_kinase PF01583.20 ORZ01095.1 - 0.005 16.7 0.4 2.5 8.0 0.0 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 ORZ01095.1 - 0.0057 17.2 0.0 3 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORZ01095.1 - 0.0091 16.4 0.0 4.5 7.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dala_Dala_lig_N PF01820.21 ORZ01095.1 - 0.015 15.8 0.1 6 7.4 0.0 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus AAA_24 PF13479.6 ORZ01095.1 - 0.022 14.5 0.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORZ01095.1 - 0.049 13.4 0.0 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 ORZ01095.1 - 0.063 13.4 0.1 11 6.1 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 ORZ01095.1 - 0.079 12.1 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 ORZ01095.1 - 0.11 11.6 0.4 8.5 5.5 0.1 2.7 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 ORZ01095.1 - 0.11 12.3 0.0 19 5.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 ORZ01095.1 - 0.24 11.0 2.8 9.9 5.7 0.2 3.5 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 ORZ01095.1 - 0.76 9.5 3.6 34 4.1 0.1 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF87 PF01935.17 ORZ01095.1 - 6.1 6.9 6.0 8.1 6.5 0.1 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain ABA_GPCR PF12430.8 ORZ01096.1 - 1.6e-39 135.5 10.3 1.6e-39 135.5 10.3 3.2 2 1 2 4 4 4 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 ORZ01096.1 - 1.6e-16 60.1 0.2 6.5e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal PrlF_antitoxin PF15937.5 ORZ01096.1 - 0.047 14.1 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin PI3K_P85_iSH2 PF16454.5 ORZ01096.1 - 0.15 11.7 0.8 0.28 10.8 0.8 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HalX PF08663.10 ORZ01096.1 - 0.72 10.2 4.6 6.5 7.1 0.2 2.3 2 0 0 2 2 2 0 HalX domain RRM_1 PF00076.22 ORZ01097.1 - 1.1e-05 25.1 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORZ01097.1 - 0.24 11.0 0.6 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACOX PF01756.19 ORZ01098.1 - 4.1e-50 169.8 0.0 9.6e-50 168.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORZ01098.1 - 1.2e-19 70.3 0.0 2.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORZ01098.1 - 7.4e-18 65.3 0.2 2.3e-17 63.7 0.2 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORZ01098.1 - 9.2e-09 35.7 0.8 4.3e-08 33.5 0.8 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 ORZ01099.1 - 1.2e-74 251.5 0.1 1.4e-74 251.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ01099.1 - 2e-14 54.3 0.3 5e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4292 PF14125.6 ORZ01099.1 - 0.033 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) MFS_1 PF07690.16 ORZ01100.1 - 4.3e-43 147.6 42.5 5.2e-40 137.4 23.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ01100.1 - 1.8e-06 27.1 15.0 1.8e-06 27.1 15.0 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 ORZ01101.1 - 7.6e-79 265.0 0.0 8.5e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORZ01102.1 - 4.7e-84 282.1 0.0 5.3e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORZ01103.1 - 2e-79 266.9 0.0 2.3e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0176_N PF17773.1 ORZ01104.1 - 7e-18 64.8 0.0 1.5e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 ORZ01104.1 - 1.4e-14 54.1 11.3 3.6e-14 52.9 11.3 1.7 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 ORZ01104.1 - 3.3e-07 30.8 0.0 8.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Ta0938 PF11494.8 ORZ01104.1 - 0.075 13.3 4.4 0.17 12.2 4.4 1.5 1 0 0 1 1 1 0 Ta0938 Aa_trans PF01490.18 ORZ01105.1 - 3.4e-90 302.7 35.0 4e-90 302.5 35.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATP1G1_PLM_MAT8 PF02038.16 ORZ01105.1 - 0.81 9.2 2.6 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family MFS_1 PF07690.16 ORZ01106.1 - 4.5e-22 78.4 30.0 5.1e-20 71.7 29.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2615 PF11027.8 ORZ01106.1 - 0.18 11.9 0.0 8.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Lipase_GDSL PF00657.22 ORZ01107.1 - 8.2e-08 32.5 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORZ01107.1 - 9.8e-05 22.8 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 ORZ01107.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily COX6B PF02297.17 ORZ01108.1 - 6.1e-24 84.1 3.8 7e-24 83.9 3.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 ORZ01108.1 - 0.0021 18.3 3.8 0.1 12.9 3.3 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 HEM4 PF02602.15 ORZ01109.1 - 4.5e-45 153.8 0.1 5.1e-45 153.6 0.1 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Polysacc_deac_1 PF01522.21 ORZ01110.1 - 4.8e-23 81.4 0.0 1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase BUD22 PF09073.10 ORZ01110.1 - 0.13 11.5 0.5 0.18 11.1 0.5 1.1 1 0 0 1 1 1 0 BUD22 Secretin_N_2 PF07655.13 ORZ01110.1 - 0.48 11.0 14.9 0.077 13.5 8.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain RAP1 PF07218.11 ORZ01110.1 - 0.85 7.8 9.6 1.3 7.2 9.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MIF4G PF02854.19 ORZ01111.1 - 5.7e-47 160.1 2.4 9.5e-47 159.4 2.4 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 ORZ01111.1 - 0.0029 17.8 0.1 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Hamartin PF04388.12 ORZ01111.1 - 5.9 5.4 34.7 14 4.2 34.7 1.8 1 0 0 1 1 1 0 Hamartin protein F-box PF00646.33 ORZ01112.1 - 0.00043 20.1 1.8 0.0025 17.6 0.0 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORZ01112.1 - 0.039 13.9 0.3 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 F-box-like PPO1_DWL PF12142.8 ORZ01112.1 - 0.098 12.5 0.3 0.21 11.4 0.3 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain CAP_GLY PF01302.25 ORZ01113.1 - 3.4e-18 65.4 0.0 5.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.31 ORZ01113.1 - 4.5e-14 52.6 0.0 6.5e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain L51_S25_CI-B8 PF05047.16 ORZ01114.1 - 1.3e-11 44.2 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GET2 PF08690.10 ORZ01115.1 - 6.8e-13 49.0 8.2 1.6e-12 47.8 8.2 1.6 1 1 0 1 1 1 1 GET complex subunit GET2 Acyltransferase PF01553.21 ORZ01116.1 - 0.0027 17.3 0.0 0.0053 16.4 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase 2-oxogl_dehyd_N PF16078.5 ORZ01116.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus DUF4306 PF14154.6 ORZ01116.1 - 0.17 12.0 1.2 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) BBS2_Mid PF14783.6 ORZ01117.1 - 0.01 15.8 0.0 2.8 8.0 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 ORZ01117.1 - 0.016 15.8 0.1 0.13 12.9 0.2 2.4 1 1 2 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ORZ01117.1 - 0.049 13.8 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 FG-GAP repeat Itfg2 PF15907.5 ORZ01117.1 - 0.18 10.8 0.1 7.6 5.5 0.0 2.1 1 1 1 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Sec2p PF06428.11 ORZ01118.1 - 4.4e-12 45.8 12.1 1e-11 44.6 12.1 1.6 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p NinD PF17466.2 ORZ01118.1 - 0.029 14.5 0.3 0.15 12.2 0.8 1.9 2 0 0 2 2 2 0 Family of unknown function Spc7 PF08317.11 ORZ01118.1 - 0.032 13.1 6.7 0.043 12.7 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 ORZ01118.1 - 0.16 11.5 6.5 0.23 11.0 6.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 ORZ01118.1 - 1.7 6.0 14.7 2.2 5.7 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ubiquitin PF00240.23 ORZ01119.1 - 1.1e-11 44.3 0.1 1.7e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 ORZ01119.1 - 2.9e-08 34.2 0.2 6e-08 33.2 0.2 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORZ01119.1 - 2.7e-06 27.5 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 ORZ01119.1 - 0.0052 16.6 0.1 0.0077 16.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cobl PF09469.10 ORZ01119.1 - 0.047 14.0 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain NIR_SIR_ferr PF03460.17 ORZ01119.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain UBX PF00789.20 ORZ01119.1 - 0.091 13.0 0.1 0.11 12.7 0.1 1.3 1 1 0 1 1 1 0 UBX domain DUF2407_C PF13373.6 ORZ01120.1 - 3.9e-25 88.7 10.8 2.1e-24 86.3 10.8 1.8 1 1 0 1 1 1 1 DUF2407 C-terminal domain MtrB PF05440.12 ORZ01120.1 - 0.082 13.3 0.8 16 6.0 0.3 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Steroid_dh PF02544.16 ORZ01121.1 - 5.3e-19 68.7 0.9 9.1e-19 67.9 0.9 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORZ01121.1 - 0.015 15.7 0.2 0.015 15.7 0.2 2.7 3 0 0 3 3 3 0 Phospholipid methyltransferase DUF4149 PF13664.6 ORZ01121.1 - 0.041 14.2 0.6 0.22 11.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) ProRS-C_1 PF09180.11 ORZ01122.1 - 3.6e-25 87.9 0.2 7.2e-25 87.0 0.2 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 ORZ01122.1 - 2.1e-21 75.9 0.0 5.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORZ01122.1 - 3.8e-18 66.1 0.0 8.4e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 ORZ01122.1 - 2.8e-12 46.8 0.5 5.6e-12 45.8 0.5 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_60s PF00428.19 ORZ01122.1 - 0.0027 18.3 3.6 0.0027 18.3 3.6 2.8 3 0 0 3 3 3 1 60s Acidic ribosomal protein UBN_AB PF14075.6 ORZ01122.1 - 0.14 11.9 0.4 0.23 11.2 0.4 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain ATG_C PF09333.11 ORZ01123.1 - 5.6e-18 65.1 0.2 1.6e-17 63.6 0.2 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 ORZ01123.1 - 5.6e-17 61.9 0.1 2e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 ORZ01123.1 - 9.1e-11 41.7 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 ORZ01123.1 - 5.3e-06 26.3 0.0 2.1e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal DUF4850 PF16142.5 ORZ01123.1 - 0.043 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) Topoisom_bac PF01131.20 ORZ01124.1 - 1.4e-98 330.6 0.0 1.7e-98 330.3 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 ORZ01124.1 - 2.2e-07 31.0 0.0 4.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Poty_coat PF00767.18 ORZ01124.1 - 0.0026 17.4 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Potyvirus coat protein MarR_2 PF12802.7 ORZ01124.1 - 0.033 14.1 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 MarR family Zap1_zf2 PF18217.1 ORZ01124.1 - 2.3 8.3 3.9 1.3 9.1 0.4 2.3 2 0 0 2 2 2 0 Zap1 zinc finger 2 Toprim PF01751.22 ORZ01125.1 - 5.3e-05 23.4 0.0 7.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Toprim domain Mg_trans_NIPA PF05653.14 ORZ01127.1 - 1.2e-103 346.3 23.2 1.4e-103 346.1 23.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORZ01127.1 - 7e-07 29.5 9.8 7e-07 29.5 9.8 4.2 2 2 1 3 3 3 2 EamA-like transporter family DUF2937 PF11157.8 ORZ01127.1 - 3.3 7.4 5.1 23 4.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) M16C_assoc PF08367.11 ORZ01128.1 - 2e-79 266.3 0.0 3.2e-79 265.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 ORZ01128.1 - 1.5e-30 106.5 0.0 1.8e-22 80.3 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORZ01128.1 - 2.8e-08 33.9 0.1 5.5e-05 23.2 0.0 3.7 3 1 0 3 3 3 2 Insulinase (Peptidase family M16) DUF3584 PF12128.8 ORZ01128.1 - 0.043 11.3 0.4 0.061 10.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ICL PF00463.21 ORZ01129.1 - 3e-265 880.7 2.6 3.4e-265 880.5 2.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORZ01129.1 - 2.9e-09 36.8 0.0 6.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2513 PF10711.9 ORZ01130.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.4 2 1 1 3 3 3 0 Hypothetical protein (DUF2513) Laminin_II PF06009.12 ORZ01130.1 - 0.36 10.8 23.7 2.6 8.1 2.9 3.9 1 1 3 4 4 4 0 Laminin Domain II Endotoxin_C2 PF18449.1 ORZ01130.1 - 0.44 10.9 10.7 1.6 9.1 0.1 4.6 5 0 0 5 5 4 0 Delta endotoxin BicD PF09730.9 ORZ01130.1 - 1.1 7.6 34.9 0.094 11.1 21.3 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D Fez1 PF06818.15 ORZ01130.1 - 1.7 9.0 35.2 0.52 10.7 13.1 2.1 1 1 1 2 2 2 0 Fez1 MscS_porin PF12795.7 ORZ01130.1 - 2.1 7.8 44.5 0.66 9.5 18.7 2.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF1192 PF06698.11 ORZ01130.1 - 2.3 8.3 11.5 19 5.4 0.3 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 ORZ01130.1 - 3.2 7.0 36.8 0.66 9.3 18.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) AIP3 PF03915.13 ORZ01130.1 - 3.3 6.7 27.8 6.4 5.8 23.5 2.4 1 1 1 2 2 2 0 Actin interacting protein 3 HMMR_N PF15905.5 ORZ01130.1 - 4 6.8 36.3 3.4 7.0 27.6 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 ORZ01130.1 - 4.6 6.8 40.0 2.2 7.9 19.0 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF745 PF05335.13 ORZ01130.1 - 4.7 6.9 37.4 4.2 7.0 16.9 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Golgin_A5 PF09787.9 ORZ01130.1 - 6.3 6.2 37.2 4.1 6.8 6.1 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 EHN PF06441.12 ORZ01130.1 - 8.3 6.8 9.7 22 5.5 2.3 3.0 1 1 1 2 2 2 0 Epoxide hydrolase N terminus F-box-like PF12937.7 ORZ01131.1 - 0.0014 18.5 1.1 0.0037 17.1 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ01131.1 - 0.9 9.5 4.9 0.55 10.2 1.9 2.3 2 0 0 2 2 2 0 F-box domain RINGv PF12906.7 ORZ01132.1 - 2.6e-07 30.6 9.5 4.7e-07 29.8 9.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ORZ01132.1 - 0.00095 19.5 6.6 0.0018 18.5 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 ORZ01132.1 - 0.0094 16.1 5.0 0.018 15.2 5.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.6 ORZ01132.1 - 0.069 13.0 6.4 0.15 11.9 6.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 ORZ01132.1 - 0.13 12.1 5.6 0.24 11.3 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORZ01132.1 - 0.19 11.6 7.6 0.34 10.8 7.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 ORZ01132.1 - 1.1 9.6 4.5 2.8 8.3 4.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORZ01132.1 - 7.1 6.6 7.0 28 4.6 7.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glucosamine_iso PF01182.20 ORZ01133.1 - 3.8e-22 79.3 0.0 6.4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF1635 PF07795.11 ORZ01133.1 - 0.0045 16.9 1.7 0.0073 16.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Planc_extracel PF07595.12 ORZ01133.1 - 0.021 14.6 1.4 0.04 13.7 1.4 1.5 1 0 0 1 1 1 0 Planctomycete extracellular HATPase_c PF02518.26 ORZ01134.1 - 9.1e-29 100.2 0.0 3e-28 98.6 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORZ01134.1 - 2.3e-24 85.7 1.0 2e-22 79.5 1.0 2.8 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORZ01134.1 - 1.7e-14 53.6 1.3 1.7e-14 53.6 1.3 2.4 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Patatin PF01734.22 ORZ01134.1 - 0.28 11.3 1.9 0.73 10.0 0.1 2.5 2 0 0 2 2 2 0 Patatin-like phospholipase Dicty_REP PF05086.12 ORZ01134.1 - 0.49 8.3 5.0 1.3 6.9 5.0 1.6 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glycos_transf_2 PF00535.26 ORZ01135.1 - 1.3e-34 119.5 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORZ01135.1 - 3.3e-13 50.1 0.0 4.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORZ01135.1 - 6.5e-06 25.8 0.0 9.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORZ01135.1 - 0.027 13.9 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 ORZ01135.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Rab3-GTPase_cat PF13890.6 ORZ01136.1 - 8.7e-59 197.8 1.6 1.6e-58 196.9 0.7 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit RRN3 PF05327.11 ORZ01136.1 - 0.096 11.2 1.8 0.33 9.4 2.5 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_C14 PF00656.22 ORZ01137.1 - 3.6e-64 217.1 0.0 4.5e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF725 PF05267.12 ORZ01137.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) RNA_pol_Rpb5_C PF01191.19 ORZ01139.1 - 4.5e-34 116.2 0.3 1e-33 115.0 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 ORZ01139.1 - 1.2e-29 102.7 0.1 2.1e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 ORZ01139.1 - 0.023 14.7 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease adh_short PF00106.25 ORZ01140.1 - 2.8e-48 164.0 0.8 3.9e-48 163.5 0.6 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ01140.1 - 4.2e-38 131.2 0.1 6e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORZ01140.1 - 6e-06 25.9 0.2 1.1e-05 25.0 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORZ01140.1 - 1.7e-05 24.8 0.6 3.7e-05 23.7 0.6 1.5 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ORZ01140.1 - 0.066 13.3 0.6 0.14 12.2 0.6 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F-box PF00646.33 ORZ01141.1 - 0.0033 17.3 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORZ01141.1 - 0.0046 16.8 0.4 0.031 14.2 0.2 2.5 2 0 0 2 2 2 1 F-box-like DnaJ_C PF01556.18 ORZ01142.1 - 2.6e-42 144.4 0.1 3.3e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORZ01142.1 - 3e-27 94.5 1.7 5e-27 93.8 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORZ01142.1 - 1.4e-16 60.6 18.8 2.2e-16 59.9 18.8 1.3 1 0 0 1 1 1 1 DnaJ central domain PDZ_6 PF17820.1 ORZ01142.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Anti-TRAP PF15777.5 ORZ01142.1 - 0.4 10.7 15.1 1.4 8.9 1.8 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORZ01142.1 - 0.52 10.3 11.3 1.4 9.0 1.8 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lyase_1 PF00206.20 ORZ01143.1 - 1.3e-121 405.9 0.0 2e-121 405.2 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ORZ01143.1 - 1.2e-26 92.8 0.0 3e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus RPN7 PF10602.9 ORZ01144.1 - 1.6e-56 190.7 1.2 2.6e-56 190.0 1.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORZ01144.1 - 6.2e-14 52.4 0.2 2.9e-13 50.2 0.0 2.3 3 0 0 3 3 3 1 PCI domain DUF2458 PF10454.9 ORZ01144.1 - 0.0066 16.1 0.9 0.026 14.2 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) CSN8_PSD8_EIF3K PF10075.9 ORZ01144.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family SPECT1 PF18680.1 ORZ01144.1 - 0.036 13.7 0.3 0.81 9.3 0.0 2.4 2 0 0 2 2 2 0 Plasmodium host cell traversal SPECT1 TPR_2 PF07719.17 ORZ01144.1 - 0.059 13.5 1.3 0.22 11.7 1.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 ORZ01144.1 - 0.16 11.3 1.7 0.15 11.4 0.2 1.6 2 0 0 2 2 2 0 SAC3/GANP family TPR_6 PF13174.6 ORZ01144.1 - 0.65 10.8 4.8 0.48 11.2 1.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 ORZ01145.1 - 0.006 15.7 0.5 0.02 13.9 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Med13_N PF11597.8 ORZ01145.1 - 0.0067 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med3 PF11593.8 ORZ01145.1 - 0.23 10.6 10.5 0.43 9.7 10.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sugar_tr PF00083.24 ORZ01146.1 - 2.1e-105 353.2 27.6 2.4e-105 353.0 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ01146.1 - 1.1e-30 106.8 37.6 6.6e-30 104.2 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ORZ01146.1 - 0.12 12.9 2.4 0.45 11.1 2.4 2.0 1 0 0 1 1 1 0 Phage holin family 2 MFS_2 PF13347.6 ORZ01146.1 - 9.5 4.6 37.4 0.25 9.8 5.8 3.3 2 2 2 4 4 4 0 MFS/sugar transport protein ADH_N PF08240.12 ORZ01147.1 - 1e-27 96.2 2.9 1e-27 96.2 2.9 2.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ01147.1 - 2.1e-20 73.1 0.1 3.8e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORZ01147.1 - 2.2e-10 40.4 0.1 3.4e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORZ01147.1 - 6.1e-06 27.3 0.0 1.3e-05 26.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 ORZ01147.1 - 0.00043 20.8 0.1 0.00092 19.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORZ01147.1 - 0.00044 20.6 0.0 0.00099 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 ORZ01147.1 - 0.00046 19.6 1.3 0.0012 18.2 0.9 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORZ01147.1 - 0.0012 18.2 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORZ01147.1 - 0.0016 17.8 0.1 0.0028 16.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORZ01147.1 - 0.0019 17.9 0.8 0.0027 17.4 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORZ01147.1 - 0.0025 16.6 0.1 0.0034 16.1 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 ORZ01147.1 - 0.015 14.7 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ORZ01147.1 - 0.036 13.1 0.9 0.051 12.7 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 ORZ01147.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 ORZ01147.1 - 0.081 13.4 0.1 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Amidohydro_3 PF07969.11 ORZ01148.1 - 6.2e-21 75.4 7.0 3.1e-09 36.8 0.0 4.4 4 1 1 5 5 5 3 Amidohydrolase family Amidohydro_1 PF01979.20 ORZ01148.1 - 2.9e-19 69.6 0.0 1.4e-11 44.3 0.0 3.6 3 1 0 3 3 3 3 Amidohydrolase family MIT PF04212.18 ORZ01149.1 - 6.2e-10 39.0 1.2 1.9e-09 37.5 1.2 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 ORZ01149.1 - 0.00014 21.6 0.1 0.0005 19.9 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ01149.1 - 0.0005 20.3 0.3 0.0016 18.7 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ01149.1 - 0.002 18.2 0.1 0.0051 16.9 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ01149.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ01149.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat IL3 PF02059.15 ORZ01149.1 - 0.049 13.7 0.2 0.72 9.9 0.0 2.4 2 0 0 2 2 2 0 Interleukin-3 TPR_10 PF13374.6 ORZ01149.1 - 0.065 13.1 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DDE_Tnp_IS240 PF13610.6 ORZ01149.1 - 0.096 12.9 0.1 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 DDE domain BTAD PF03704.17 ORZ01149.1 - 0.21 12.0 0.9 0.87 10.0 0.3 2.2 2 1 1 3 3 3 0 Bacterial transcriptional activator domain CPCFC PF17223.3 ORZ01150.1 - 0.094 12.5 0.1 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Cuticle protein CPCFC WRKY PF03106.15 ORZ01151.1 - 1.4e-08 34.8 2.6 2.9e-08 33.8 2.6 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain Phospho_p8 PF10195.9 ORZ01151.1 - 0.079 13.5 0.6 0.22 12.1 0.6 1.8 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Kei1 PF08552.11 ORZ01152.1 - 0.0051 16.7 1.7 0.0052 16.7 0.1 1.7 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Ni_hydr_CYTB PF01292.20 ORZ01152.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 CAP_N PF01213.19 ORZ01152.1 - 0.13 11.7 3.0 0.16 11.4 3.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1748 PF08520.10 ORZ01153.1 - 9.9e-28 95.9 0.0 1.1e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Sas10 PF09368.10 ORZ01154.1 - 1.4e-25 89.5 6.5 1.4e-25 89.5 6.5 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 ORZ01154.1 - 2.1e-11 44.3 2.1 6.7e-11 42.7 0.5 2.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Bud13 PF09736.9 ORZ01155.1 - 7.7e-50 169.1 11.0 7.7e-50 169.1 11.0 2.9 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Homeodomain PF00046.29 ORZ01156.1 - 4.1e-15 55.4 0.2 8.7e-15 54.3 0.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORZ01156.1 - 0.025 14.5 5.5 0.027 14.4 0.0 3.1 3 0 0 3 3 3 0 Homeobox KN domain RanGAP1_C PF07834.11 ORZ01156.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RanGAP1 C-terminal domain CCDC24 PF15669.5 ORZ01156.1 - 9.1 6.1 7.6 0.35 10.7 1.4 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Cas1_AcylT PF07779.12 ORZ01157.1 - 5.6e-134 447.6 21.9 7.5e-134 447.2 21.9 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 ORZ01157.1 - 4e-06 26.8 0.0 6.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SPRY PF00622.28 ORZ01158.1 - 3.7e-23 81.9 0.2 6.2e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 ORZ01158.1 - 1.3e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORZ01158.1 - 0.0029 17.5 0.2 0.0061 16.5 0.2 1.5 1 0 0 1 1 1 1 LisH Ammonium_transp PF00909.21 ORZ01159.1 - 4.7e-123 410.8 26.3 5.4e-123 410.6 26.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tweety PF04906.13 ORZ01159.1 - 0.6 8.7 6.1 0.28 9.8 2.8 1.9 2 0 0 2 2 2 0 Tweety WD40 PF00400.32 ORZ01160.1 - 1e-32 111.6 12.5 1.8e-07 31.7 0.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01160.1 - 2.6e-07 30.9 0.2 0.0029 17.9 0.0 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORZ01160.1 - 0.015 14.0 0.1 3.6 6.1 0.0 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORZ01160.1 - 0.15 11.0 0.7 4.2 6.2 0.1 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Metallophos PF00149.28 ORZ01161.1 - 3.4e-10 40.8 0.6 5.2e-10 40.2 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_DNA_glyco PF02245.16 ORZ01162.1 - 0.0002 20.9 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) CUE PF02845.16 ORZ01163.1 - 9e-09 34.9 0.0 1.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 ORZ01163.1 - 0.00049 19.7 3.4 0.00089 18.8 3.4 1.4 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 ORZ01163.1 - 0.058 13.4 1.5 0.13 12.4 1.5 1.7 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 DUF3864 PF12980.7 ORZ01163.1 - 0.063 13.6 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) CAP_N PF01213.19 ORZ01163.1 - 0.13 11.8 1.1 0.14 11.6 1.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PP2C PF00481.21 ORZ01164.1 - 4.3e-16 59.3 0.0 1.6e-12 47.6 0.0 3.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORZ01164.1 - 0.0013 18.4 0.0 0.016 14.8 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C Striatin PF08232.12 ORZ01164.1 - 0.066 13.8 0.1 0.066 13.8 0.1 4.1 3 1 0 3 3 3 0 Striatin family Clat_adaptor_s PF01217.20 ORZ01165.1 - 2.8e-54 182.9 2.6 3.2e-54 182.7 2.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.21 ORZ01166.1 - 1.7e-52 178.5 0.0 2.1e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MBA1 PF07961.11 ORZ01166.1 - 0.019 14.0 0.3 0.029 13.4 0.3 1.4 1 1 0 1 1 1 0 MBA1-like protein Zn_clus PF00172.18 ORZ01167.1 - 6e-09 35.9 10.5 1.5e-08 34.7 10.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-patch PF01585.23 ORZ01168.1 - 5.9e-14 51.7 1.4 1.2e-13 50.7 1.4 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 ORZ01168.1 - 5.7e-05 23.3 6.5 0.00014 22.1 6.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 ORZ01168.1 - 7.2e-05 22.8 0.5 7.2e-05 22.8 0.5 2.1 2 0 0 2 2 2 1 G-patch domain zf-met PF12874.7 ORZ01168.1 - 0.00017 21.9 0.5 0.00034 20.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 ORZ01168.1 - 0.0027 17.8 2.5 0.005 16.9 2.5 1.5 1 0 0 1 1 1 1 DBF zinc finger AAA_11 PF13086.6 ORZ01168.1 - 2.2 8.0 10.4 3.3 7.4 10.4 1.3 1 0 0 1 1 1 0 AAA domain UPF0172 PF03665.13 ORZ01168.1 - 6.4 6.8 10.4 0.15 12.0 2.8 2.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0172) adh_short_C2 PF13561.6 ORZ01169.1 - 2.6e-62 210.5 0.7 2.9e-62 210.3 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORZ01169.1 - 2e-56 190.5 2.0 2.4e-56 190.3 2.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORZ01169.1 - 2e-20 73.5 1.9 3.4e-20 72.7 1.9 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORZ01169.1 - 1.7e-11 44.1 0.3 9.6e-11 41.6 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORZ01169.1 - 2.9e-05 24.1 1.3 5.6e-05 23.1 1.3 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORZ01169.1 - 0.0021 17.2 0.2 0.0035 16.5 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORZ01169.1 - 0.036 13.6 0.4 0.036 13.6 0.4 1.8 2 0 0 2 2 2 0 NmrA-like family ADH_zinc_N PF00107.26 ORZ01169.1 - 0.046 13.7 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HMG_box PF00505.19 ORZ01170.1 - 2.4e-40 136.8 3.8 2.8e-20 72.5 0.5 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ01170.1 - 3.3e-32 110.9 2.5 4.6e-15 56.0 0.2 2.3 2 0 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 ORZ01170.1 - 0.0011 19.2 5.4 0.0029 17.8 0.7 2.8 1 1 2 3 3 3 1 Protamine and protamine like HMG_box_5 PF14887.6 ORZ01170.1 - 0.0016 18.3 1.3 0.0079 16.1 0.0 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CHDNT PF08073.12 ORZ01170.1 - 0.028 14.4 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 CHDNT (NUC034) domain Ofd1_CTDD PF10637.9 ORZ01170.1 - 0.19 11.0 2.6 0.37 10.1 0.5 2.0 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF1104 PF06518.11 ORZ01170.1 - 0.19 12.1 1.9 1.6 9.2 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) Exo_endo_phos PF03372.23 ORZ01171.1 - 3.2e-23 82.5 0.1 8.9e-23 81.0 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 ORZ01171.1 - 1e-08 35.3 8.4 0.00031 21.0 1.6 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORZ01171.1 - 1.6e-08 34.1 10.8 9.5e-06 25.3 3.8 2.4 1 1 0 2 2 2 2 Leucine rich repeat WW_FCH_linker PF16623.5 ORZ01171.1 - 0.063 14.0 1.4 0.15 12.9 1.4 1.6 1 0 0 1 1 1 0 Unstructured linker region between on GAS7 protein LRR_9 PF14580.6 ORZ01171.1 - 0.1 12.1 0.6 0.23 10.9 0.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 ORZ01171.1 - 0.12 13.0 6.0 24 6.0 0.2 4.8 3 1 1 4 4 4 0 Leucine Rich Repeat adh_short_C2 PF13561.6 ORZ01172.1 - 8.8e-47 159.6 3.2 1.1e-46 159.4 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORZ01172.1 - 7.4e-43 146.3 0.9 9.9e-43 145.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORZ01172.1 - 0.00046 20.2 1.0 0.0022 18.0 1.0 1.9 1 1 0 1 1 1 1 KR domain Met_asp_mut_E PF06368.11 ORZ01172.1 - 0.072 11.6 0.0 0.089 11.2 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) RNA_pol_Rpb8 PF03870.15 ORZ01173.1 - 3.1e-49 166.7 0.1 4e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 ORZ01173.1 - 0.036 14.1 0.1 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G PQ-loop PF04193.14 ORZ01174.1 - 1.8e-24 85.2 10.1 3.2e-12 46.0 0.1 2.9 3 0 0 3 3 3 2 PQ loop repeat Cyt_c_ox_IV PF12270.8 ORZ01174.1 - 0.025 14.7 1.4 0.075 13.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF2273 PF10031.9 ORZ01174.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.9 5 0 0 5 5 5 0 Small integral membrane protein (DUF2273) 4HBT PF03061.22 ORZ01175.1 - 7.3e-13 48.7 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_trans_2_3 PF13632.6 ORZ01176.1 - 1.3e-13 51.3 0.7 2.6e-13 50.3 0.7 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 HLH PF00010.26 ORZ01177.1 - 1.2e-17 63.6 4.2 1.2e-17 63.6 4.2 2.0 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain MerR-DNA-bind PF09278.11 ORZ01177.1 - 0.0016 18.9 3.0 0.26 11.8 0.5 2.1 2 0 0 2 2 2 2 MerR, DNA binding ParD PF09386.10 ORZ01177.1 - 0.034 14.5 0.8 0.27 11.6 0.4 2.3 1 1 1 2 2 2 0 Antitoxin ParD Tmemb_cc2 PF10267.9 ORZ01177.1 - 0.14 11.3 0.3 0.14 11.3 0.3 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein HlyIII PF03006.20 ORZ01178.1 - 2e-59 201.0 22.3 4.4e-59 199.9 22.2 1.6 2 0 0 2 2 2 1 Haemolysin-III related SPC12 PF06645.13 ORZ01178.1 - 0.0001 22.3 0.6 0.00034 20.6 0.6 1.9 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Apolipoprotein PF01442.18 ORZ01178.1 - 0.0013 18.7 12.3 0.002 18.1 12.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Ferritin-like PF12902.7 ORZ01178.1 - 0.0036 17.2 1.7 0.0048 16.8 1.2 1.4 1 1 0 1 1 1 1 Ferritin-like ABC_tran_CTD PF16326.5 ORZ01178.1 - 0.062 13.5 9.5 3.9 7.8 4.9 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain BshC PF10079.9 ORZ01178.1 - 0.063 12.0 4.6 0.092 11.5 4.6 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Muted PF14942.6 ORZ01178.1 - 0.088 13.2 12.0 0.49 10.7 5.3 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein BLOC1_2 PF10046.9 ORZ01178.1 - 0.5 10.7 7.7 0.7 10.2 5.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5446 PF17522.2 ORZ01178.1 - 0.56 10.4 2.4 2.3 8.5 0.0 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5446) CCDC-167 PF15188.6 ORZ01178.1 - 1 9.8 7.4 2.7 8.4 0.8 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 COG2 PF06148.11 ORZ01178.1 - 3.8 7.6 8.6 1.5 8.9 4.9 2.0 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 ORZ01178.1 - 3.9 7.5 6.4 5.4 7.1 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Halogen_Hydrol PF10112.9 ORZ01178.1 - 4.2 7.3 10.0 4.6 7.2 6.9 2.5 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Sugar_tr PF00083.24 ORZ01180.1 - 3.8e-129 431.5 28.6 5.1e-129 431.0 28.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ01180.1 - 1.3e-31 109.8 55.1 3.6e-23 82.1 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PelG PF16933.5 ORZ01180.1 - 2.1e-05 23.6 8.0 2.1e-05 23.6 8.0 2.5 3 0 0 3 3 3 1 Putative exopolysaccharide Exporter (EPS-E) OATP PF03137.20 ORZ01180.1 - 0.023 13.0 0.3 0.023 13.0 0.3 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SIS PF01380.22 ORZ01181.1 - 2.7e-21 75.8 0.0 4.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 ORZ01181.1 - 1.4e-06 28.4 0.2 0.0084 16.1 0.2 2.4 1 1 1 2 2 2 2 SIS domain CBS PF00571.28 ORZ01181.1 - 2.5e-05 24.6 0.1 0.002 18.5 0.0 3.4 4 0 0 4 4 4 1 CBS domain DUF2529 PF10740.9 ORZ01181.1 - 0.12 12.1 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) Raptor_N PF14538.6 ORZ01182.1 - 1.8e-66 222.6 0.0 3.5e-66 221.7 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 ORZ01182.1 - 3.2e-12 46.7 13.9 0.0023 18.7 0.4 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.22 ORZ01182.1 - 1.1e-08 34.6 6.1 0.0093 16.2 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 ORZ01182.1 - 1.1e-06 28.9 0.1 0.00017 21.9 0.0 3.5 2 1 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 ORZ01182.1 - 7.9e-05 22.8 0.1 0.0076 16.3 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORZ01182.1 - 0.0027 18.1 0.7 0.95 10.0 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat PDE6_gamma PF04868.12 ORZ01182.1 - 0.017 15.4 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit PCI PF01399.27 ORZ01183.1 - 3.1e-21 75.9 4.5 3.8e-21 75.5 1.5 2.6 3 0 0 3 3 3 1 PCI domain TLE_N PF03920.15 ORZ01183.1 - 0.02 15.0 2.3 0.058 13.5 0.8 2.4 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Vta1 PF04652.16 ORZ01184.1 - 2.6e-47 160.4 0.3 4.4e-47 159.7 0.0 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 ORZ01184.1 - 4.2e-15 55.2 0.4 4.2e-15 55.2 0.4 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain CsbD PF05532.12 ORZ01185.1 - 2.2e-11 43.5 6.0 2.2e-11 43.5 6.0 1.9 1 1 1 2 2 2 1 CsbD-like DUF883 PF05957.13 ORZ01185.1 - 0.082 13.5 0.0 0.097 13.3 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) NAD_kinase PF01513.21 ORZ01186.1 - 2.9e-70 236.8 0.0 2.4e-69 233.8 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase GAT PF03127.14 ORZ01187.1 - 9.3e-10 38.7 0.6 3.4e-09 36.9 0.6 2.1 1 0 0 1 1 1 1 GAT domain LRR_6 PF13516.6 ORZ01187.1 - 3.1e-05 23.7 29.5 0.37 11.0 0.2 9.6 10 1 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 ORZ01187.1 - 0.21 12.1 21.7 1.4 9.5 0.4 6.9 3 1 6 9 9 9 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORZ01187.1 - 0.39 11.5 9.8 2.5e+02 2.9 0.0 7.8 10 0 0 10 10 10 0 Leucine Rich Repeat CENP-B_dimeris PF09026.10 ORZ01187.1 - 2 8.8 8.4 1 9.8 3.4 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ctr PF04145.15 ORZ01188.1 - 7.6e-07 29.8 0.8 8.6e-07 29.7 0.8 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Ceramidase_alk PF04734.13 ORZ01189.1 - 5.2e-200 665.4 0.0 6.2e-200 665.1 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 ORZ01189.1 - 2.7e-43 147.7 0.1 4.4e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Methyltransf_16 PF10294.9 ORZ01191.1 - 2.6e-45 154.3 0.0 3.5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 ORZ01191.1 - 0.0041 16.9 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ01191.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 ORZ01191.1 - 0.017 15.8 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M24 PF00557.24 ORZ01192.1 - 2.8e-53 180.7 0.1 3.4e-53 180.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORZ01192.1 - 6e-21 74.5 11.3 1.5e-20 73.2 11.3 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORZ01192.1 - 0.00014 21.8 7.2 0.00033 20.7 7.2 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORZ01192.1 - 0.15 12.0 5.5 0.44 10.5 5.5 1.9 1 0 0 1 1 1 0 HIT zinc finger Trehalose_PPase PF02358.16 ORZ01193.1 - 1.7e-66 223.7 0.0 2.5e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.21 ORZ01193.1 - 1.6e-38 132.7 0.0 2.8e-37 128.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 DUF4763 PF15960.5 ORZ01193.1 - 0.063 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) EDS1_EP PF18117.1 ORZ01195.1 - 0.087 13.3 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain Mgm101p PF06420.12 ORZ01196.1 - 1e-89 298.5 0.0 1.4e-89 298.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Rab5ip PF07019.12 ORZ01198.1 - 2.5e-18 66.4 8.2 3e-18 66.2 8.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF1478 PF07349.11 ORZ01198.1 - 0.043 13.7 0.1 0.048 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) Aminotran_1_2 PF00155.21 ORZ01199.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II TIG PF01833.24 ORZ01200.1 - 1.1e-11 44.7 0.2 2.4e-11 43.5 0.2 1.7 1 0 0 1 1 1 1 IPT/TIG domain Hamartin PF04388.12 ORZ01200.1 - 0.79 8.3 8.6 1 8.0 8.6 1.1 1 0 0 1 1 1 0 Hamartin protein zf-C2H2 PF00096.26 ORZ01201.1 - 3.9e-08 33.3 8.0 0.00042 20.6 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ01201.1 - 8.5e-06 26.2 12.1 0.0063 17.3 1.6 3.1 4 0 0 4 4 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORZ01201.1 - 0.0012 19.1 7.6 0.019 15.3 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORZ01201.1 - 0.0015 18.5 6.1 0.31 11.1 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORZ01201.1 - 0.002 18.0 3.1 0.002 18.0 3.1 2.9 2 1 0 2 2 2 1 zinc-finger of a C2HC-type Prok-RING_1 PF14446.6 ORZ01201.1 - 0.019 14.9 1.0 3 7.8 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_11 PF16622.5 ORZ01201.1 - 0.02 14.6 4.1 1.2 8.9 0.7 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 ORZ01201.1 - 0.021 15.5 2.9 0.021 15.5 2.9 2.1 2 1 1 3 3 3 0 zinc-ribbon family zf-H2C2_2 PF13465.6 ORZ01201.1 - 0.024 15.0 0.8 0.024 15.0 0.8 2.5 3 0 0 3 3 3 0 Zinc-finger double domain HypA PF01155.19 ORZ01201.1 - 0.028 14.4 4.0 1.5 8.9 4.0 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sec16 PF12932.7 ORZ01201.1 - 0.034 14.7 1.0 0.047 14.3 1.0 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region zf-met PF12874.7 ORZ01201.1 - 0.061 13.7 2.5 7.6 7.1 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 ORZ01201.1 - 0.18 11.8 5.7 5.4 7.1 2.3 2.5 1 1 1 2 2 2 0 BED zinc finger Lin-8 PF03353.15 ORZ01201.1 - 0.35 10.4 8.8 0.041 13.5 4.8 1.5 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist zinc_ribbon_4 PF13717.6 ORZ01201.1 - 5 7.1 8.4 3.9 7.5 1.9 2.5 1 1 1 2 2 2 0 zinc-ribbon domain PIG-H PF10181.9 ORZ01202.1 - 8.5e-19 67.2 0.1 2.1e-18 66.0 0.2 1.6 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component YbhQ PF11076.8 ORZ01202.1 - 0.11 12.6 0.9 0.46 10.5 0.1 2.2 2 1 0 2 2 2 0 Putative inner membrane protein YbhQ WD40 PF00400.32 ORZ01203.1 - 2.4e-42 142.1 10.0 1.8e-08 34.9 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORZ01203.1 - 1.4e-09 37.4 1.2 0.2 10.5 0.0 5.2 1 1 3 5 5 5 5 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 ORZ01203.1 - 2.1e-09 37.5 1.4 0.41 11.0 0.2 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORZ01203.1 - 2.7e-07 29.6 5.0 0.34 9.5 0.1 5.0 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORZ01203.1 - 0.00073 18.4 0.0 4.7 5.8 0.0 4.2 1 1 4 5 5 5 2 Nup133 N terminal like eIF2A PF08662.11 ORZ01203.1 - 0.0013 18.7 0.4 0.99 9.3 0.1 2.9 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 ORZ01203.1 - 0.0046 15.9 1.8 0.017 14.1 0.1 2.6 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 ORZ01203.1 - 0.01 15.6 1.0 1.8 8.2 0.1 3.4 2 1 2 4 4 4 0 TUP1-like enhancer of split MMS1_N PF10433.9 ORZ01203.1 - 0.015 13.9 0.0 0.15 10.7 0.0 2.4 1 1 1 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Frtz PF11768.8 ORZ01203.1 - 0.038 12.3 0.1 1 7.6 0.0 2.7 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_M28 PF04389.17 ORZ01204.1 - 2.4e-46 157.9 0.0 3.7e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORZ01204.1 - 3.3e-06 26.9 0.0 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORZ01204.1 - 0.00062 18.9 0.0 0.0026 16.8 0.0 1.9 2 1 1 3 3 3 1 M42 glutamyl aminopeptidase Flavin_Reduct PF01613.18 ORZ01205.1 - 8.5e-40 136.3 0.1 1.2e-39 135.8 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain AKAP7_NLS PF10469.9 ORZ01206.1 - 3.1e-47 161.2 0.4 9.7e-47 159.5 0.0 1.7 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 ORZ01206.1 - 1.9e-11 43.6 2.4 3.5e-11 42.8 2.4 1.4 1 0 0 1 1 1 1 KH domain SLS PF14611.6 ORZ01206.1 - 7.5e-05 22.7 0.5 0.0001 22.2 0.5 1.4 1 1 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator LigT_PEase PF02834.16 ORZ01206.1 - 0.0024 18.0 0.0 2.8 8.2 0.0 2.9 2 2 0 2 2 2 2 LigT like Phosphoesterase Corona_NS2A PF05213.12 ORZ01206.1 - 0.12 11.7 0.1 2.4 7.4 0.0 2.3 2 1 0 2 2 2 0 Coronavirus NS2A protein Cullin PF00888.22 ORZ01207.1 - 4.6e-150 501.2 11.9 5.8e-150 500.9 11.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORZ01207.1 - 9.7e-21 73.6 1.0 2.5e-20 72.3 1.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4423 PF14394.6 ORZ01207.1 - 0.025 14.3 0.2 0.1 12.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) BACK PF07707.15 ORZ01207.1 - 0.27 11.3 5.1 8.7 6.5 0.4 3.4 3 0 0 3 3 3 0 BTB And C-terminal Kelch PH PF00169.29 ORZ01208.1 - 2.5e-09 37.6 0.1 7.6e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 PH domain Homeodomain PF00046.29 ORZ01209.1 - 2.8e-19 68.7 3.0 5.7e-19 67.7 3.0 1.5 1 0 0 1 1 1 1 Homeodomain SART-1 PF03343.13 ORZ01209.1 - 0.067 11.8 4.7 0.091 11.3 4.7 1.1 1 0 0 1 1 1 0 SART-1 family Homeobox_KN PF05920.11 ORZ01209.1 - 0.28 11.1 2.5 0.41 10.6 0.6 2.3 2 0 0 2 2 2 0 Homeobox KN domain CHDCT2 PF08074.11 ORZ01209.1 - 2.9 8.1 7.6 8.9 6.5 0.2 2.4 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain MA3 PF02847.17 ORZ01211.1 - 8.3e-28 96.6 0.7 1.9e-27 95.5 0.7 1.6 1 0 0 1 1 1 1 MA3 domain MRP-S26 PF14943.6 ORZ01211.1 - 0.0083 16.1 0.6 0.024 14.5 0.6 1.8 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 DUF5523 PF17661.1 ORZ01211.1 - 2.3 7.9 16.1 0.012 15.4 6.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5523) IPP-2 PF04979.14 ORZ01211.1 - 9.2 7.0 19.6 1.1 10.0 3.3 2.4 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) Myb_DNA-binding PF00249.31 ORZ01212.1 - 2.9e-11 43.4 0.5 1.7e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 ORZ01212.1 - 3e-10 40.3 0.0 9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 ORZ01212.1 - 1.5e-09 37.5 4.1 2.7e-09 36.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 ORZ01212.1 - 5.5e-05 23.3 0.1 0.00014 22.1 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 ORZ01212.1 - 0.34 11.3 6.1 0.71 10.2 6.1 1.5 1 0 0 1 1 1 0 C1 domain DUF2057 PF09829.9 ORZ01212.1 - 1.5 8.9 7.9 3.1 7.9 7.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) LETM1 PF07766.13 ORZ01213.1 - 6.3e-26 91.3 4.6 1.4e-24 86.9 4.6 2.0 1 1 0 1 1 1 1 LETM1-like protein SAP PF02037.27 ORZ01213.1 - 2.8e-05 23.7 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 SAP domain Ribosomal_L21e PF01157.18 ORZ01215.1 - 1.5e-47 159.6 4.2 1.5e-47 159.6 4.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 ORZ01215.1 - 0.0019 17.8 0.1 0.0024 17.5 0.1 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Exostosin PF03016.15 ORZ01217.1 - 4.1e-38 131.3 0.4 5.2e-38 130.9 0.4 1.0 1 0 0 1 1 1 1 Exostosin family Glyco_hydro_12 PF01670.16 ORZ01218.1 - 3.3e-49 167.8 11.6 3.9e-49 167.6 11.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Pkinase PF00069.25 ORZ01219.1 - 2.9e-62 210.4 0.5 9.2e-55 185.8 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01219.1 - 8.9e-36 123.5 0.0 7.4e-32 110.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORZ01219.1 - 7.9e-05 22.1 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORZ01219.1 - 0.00029 19.7 5.9 0.00064 18.6 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase PIN_12 PF16289.5 ORZ01219.1 - 0.0042 17.6 1.0 0.0094 16.5 1.0 1.5 1 0 0 1 1 1 1 PIN domain APH PF01636.23 ORZ01219.1 - 0.012 15.5 0.3 0.024 14.6 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peroxin-13_N PF04088.13 ORZ01219.1 - 0.074 13.3 1.0 0.15 12.4 1.0 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region YtxH PF12732.7 ORZ01220.1 - 8.6e-08 32.6 17.0 0.00029 21.3 9.1 2.6 1 1 1 2 2 2 2 YtxH-like protein Apolipoprotein PF01442.18 ORZ01220.1 - 0.0012 18.8 5.2 0.0012 18.8 5.2 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Gram_pos_anchor PF00746.21 ORZ01220.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phage_Mu_Gam PF07352.12 ORZ01220.1 - 0.013 15.5 5.6 0.022 14.7 5.6 1.4 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein CCDC154 PF15450.6 ORZ01220.1 - 0.031 12.8 5.8 0.062 11.8 5.8 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 154 DUF883 PF05957.13 ORZ01220.1 - 0.046 14.3 3.2 0.046 14.3 3.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ApoO PF09769.9 ORZ01220.1 - 0.053 13.5 3.2 2.3 8.2 0.2 2.2 1 1 1 2 2 2 0 Apolipoprotein O Hema_stalk PF08720.10 ORZ01220.1 - 0.16 11.7 2.0 0.41 10.3 0.1 2.0 1 1 1 2 2 2 0 Influenza C hemagglutinin stalk V-ATPase_G PF03179.15 ORZ01220.1 - 0.39 11.3 15.1 0.18 12.3 9.7 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF5132 PF17195.4 ORZ01220.1 - 0.8 9.8 6.8 3.2 7.9 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) DUF1664 PF07889.12 ORZ01220.1 - 1.1 9.3 6.5 4.5 7.3 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HSP9_HSP12 PF04119.12 ORZ01220.1 - 1.3 9.5 10.3 4 7.9 1.7 3.0 1 1 1 3 3 3 0 Heat shock protein 9/12 ATP-synt_B PF00430.18 ORZ01220.1 - 7.1 6.7 20.3 0.066 13.3 6.2 2.8 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) U1snRNP70_N PF12220.8 ORZ01220.1 - 7.9 7.2 7.7 2.9 8.6 0.7 2.2 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TraG_N PF07916.11 ORZ01220.1 - 8.2 5.2 5.4 11 4.7 5.3 1.4 1 1 0 1 1 1 0 TraG-like protein, N-terminal region LEA_1 PF03760.15 ORZ01220.1 - 8.7 7.1 24.9 1.6 9.4 4.9 2.8 3 0 0 3 3 3 0 Late embryogenesis abundant (LEA) group 1 Peptidase_M41 PF01434.18 ORZ01221.1 - 2.2e-66 223.4 2.2 3.5e-66 222.7 2.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORZ01221.1 - 2.9e-43 147.5 0.0 1.2e-42 145.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ01221.1 - 7.5e-12 44.9 0.0 2e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 ORZ01221.1 - 4.2e-06 26.2 0.1 5.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 ORZ01221.1 - 8e-06 25.9 0.0 2.5e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORZ01221.1 - 2.5e-05 24.7 0.3 0.00031 21.2 0.2 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORZ01221.1 - 2.9e-05 24.3 0.0 0.01 16.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 ORZ01221.1 - 8.9e-05 22.3 0.0 0.00038 20.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORZ01221.1 - 0.00017 21.8 0.2 0.0023 18.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 ORZ01221.1 - 0.0058 16.0 0.5 0.013 14.9 0.5 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ORZ01221.1 - 0.0072 15.5 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 ORZ01221.1 - 0.0086 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORZ01221.1 - 0.012 16.1 0.0 0.035 14.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 ORZ01221.1 - 0.015 15.4 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORZ01221.1 - 0.015 14.7 0.3 0.71 9.2 0.0 3.2 3 1 1 4 4 4 0 KaiC AAA_25 PF13481.6 ORZ01221.1 - 0.016 14.8 0.6 0.34 10.5 0.3 2.6 1 1 0 2 2 2 0 AAA domain NACHT PF05729.12 ORZ01221.1 - 0.017 15.0 0.6 0.16 11.9 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 ORZ01221.1 - 0.033 14.4 0.1 0.093 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 ORZ01221.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORZ01221.1 - 0.04 14.1 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORZ01221.1 - 0.057 12.9 0.1 0.22 11.0 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 ORZ01221.1 - 0.071 12.8 0.0 0.28 10.9 0.0 2.0 3 0 0 3 3 1 0 Sigma-54 interaction domain CEP44 PF15007.6 ORZ01221.1 - 0.082 13.1 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 Centrosomal spindle body, CEP44 SUKH_5 PF14567.6 ORZ01221.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall AAA_24 PF13479.6 ORZ01221.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORZ01221.1 - 0.12 12.8 0.7 2.1 8.8 0.0 3.0 3 0 0 3 3 3 0 ABC transporter RNA_helicase PF00910.22 ORZ01221.1 - 0.13 12.7 0.0 2 8.9 0.0 2.6 2 1 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 ORZ01221.1 - 0.13 11.5 1.1 0.4 9.9 0.4 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.6 ORZ01221.1 - 0.23 11.8 1.7 1.6 9.1 0.3 2.9 3 0 0 3 3 3 0 AAA domain GATA PF00320.27 ORZ01222.1 - 3.6e-17 61.7 5.1 5.8e-17 61.0 5.1 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-3CxxC PF13695.6 ORZ01222.1 - 0.038 14.5 2.3 0.07 13.6 2.3 1.7 1 1 0 1 1 1 0 Zinc-binding domain zf-C2H2_3 PF13878.6 ORZ01222.1 - 0.055 13.3 1.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn-ribbon_8 PF09723.10 ORZ01222.1 - 0.061 13.5 0.3 0.093 12.9 0.3 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF2284 PF10050.9 ORZ01222.1 - 0.084 12.6 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Ribosomal_L44 PF00935.19 ORZ01222.1 - 0.15 12.5 0.6 0.15 12.5 0.6 2.1 2 0 0 2 2 2 0 Ribosomal protein L44 DMT_YdcZ PF04657.13 ORZ01223.1 - 4.9e-31 107.9 8.3 5.8e-31 107.6 8.3 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ EamA PF00892.20 ORZ01223.1 - 0.01 16.0 6.4 0.016 15.3 6.4 1.4 1 1 0 1 1 1 0 EamA-like transporter family Alk_phosphatase PF00245.20 ORZ01224.1 - 3.9 6.3 8.7 5.2 5.9 8.7 1.2 1 0 0 1 1 1 0 Alkaline phosphatase SH3_1 PF00018.28 ORZ01225.1 - 7.9e-10 38.2 0.0 2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORZ01225.1 - 3.5e-08 33.0 0.0 6.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORZ01225.1 - 2.4e-07 30.5 0.3 9.8e-07 28.5 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain Ribosomal_S14 PF00253.21 ORZ01226.1 - 2.9e-17 62.2 3.3 3.1e-17 62.0 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Abhydrolase_1 PF00561.20 ORZ01227.1 - 6.9e-21 75.0 0.1 1.2e-19 71.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORZ01227.1 - 3e-15 56.2 0.0 3.9e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORZ01227.1 - 2.7e-14 54.3 0.0 3.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ORZ01227.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORZ01227.1 - 0.0017 17.9 0.1 1 8.8 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 ORZ01227.1 - 0.0053 16.4 0.1 0.072 12.7 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 ORZ01227.1 - 0.011 15.3 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 ORZ01227.1 - 0.014 14.9 0.0 0.16 11.5 0.0 2.0 1 1 1 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 ORZ01227.1 - 0.059 13.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ORZ01227.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 ORZ01228.1 - 3.8e-48 164.1 0.0 5.1e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ORZ01228.1 - 1.5e-08 34.4 1.1 2.9e-08 33.5 1.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ORZ01228.1 - 3.1e-05 24.9 0.1 0.00015 22.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1981 PF09324.10 ORZ01228.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) NADH_dh_m_C1 PF15088.6 ORZ01228.1 - 0.89 9.2 4.2 1.9 8.2 4.2 1.5 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial PSP1 PF04468.12 ORZ01229.1 - 3.9e-34 116.8 5.4 3.9e-34 116.8 5.4 2.4 4 0 0 4 4 4 1 PSP1 C-terminal conserved region BAG PF02179.16 ORZ01229.1 - 0.014 15.8 0.4 0.014 15.8 0.4 1.9 2 0 0 2 2 2 0 BAG domain SIR2 PF02146.17 ORZ01230.1 - 7.9e-39 133.4 0.0 1.1e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Churchill PF06573.11 ORZ01230.1 - 0.36 11.2 1.5 1.7 9.0 1.2 2.2 2 0 0 2 2 2 0 Churchill protein MMR_HSR1 PF01926.23 ORZ01231.1 - 1.9e-15 56.9 2.5 5.9e-15 55.3 0.1 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORZ01231.1 - 2.2e-06 27.3 0.1 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORZ01231.1 - 8.7e-06 25.7 0.5 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 ORZ01231.1 - 0.002 17.5 0.1 0.0049 16.2 0.1 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 ORZ01231.1 - 0.0064 16.6 3.9 0.048 13.7 0.0 3.3 3 0 0 3 3 3 1 Dynamin family E1-E2_ATPase PF00122.20 ORZ01232.1 - 2e-50 170.8 0.4 4.8e-50 169.6 0.2 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 ORZ01232.1 - 2.1e-16 59.3 0.1 4.5e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORZ01232.1 - 0.0047 17.0 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2244 PF10003.9 ORZ01232.1 - 0.11 12.1 0.6 0.29 10.8 0.2 1.8 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) Holin_BlyA PF05102.12 ORZ01232.1 - 0.12 12.3 0.3 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 holin, BlyA family GATA PF00320.27 ORZ01233.1 - 1.1e-27 95.3 20.1 1.1e-15 56.9 4.0 2.6 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORZ01233.1 - 0.0018 17.7 5.1 0.019 14.4 0.5 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 ORZ01233.1 - 0.0078 16.3 7.2 0.0096 16.1 0.7 2.6 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NMD3 PF04981.13 ORZ01233.1 - 0.013 14.9 4.3 0.45 9.9 0.8 2.2 2 0 0 2 2 2 0 NMD3 family eIF-5_eIF-2B PF01873.17 ORZ01233.1 - 0.064 13.1 5.2 2.4 8.1 0.5 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 ORZ01233.1 - 0.96 9.4 12.6 0.3 11.0 0.8 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Cytochrom_c3_2 PF14537.6 ORZ01233.1 - 2 9.0 13.7 2.5 8.6 2.6 3.1 2 1 2 4 4 4 0 Cytochrome c3 Zn-ribbon_8 PF09723.10 ORZ01233.1 - 6.9 6.9 7.1 5.8 7.1 0.2 3.0 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 ORZ01233.1 - 9.4 6.4 13.4 27 4.9 2.8 3.3 1 1 2 3 3 3 0 Double zinc ribbon Acetyltransf_4 PF13420.7 ORZ01234.1 - 6e-26 91.4 0.0 7e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORZ01234.1 - 9.7e-14 52.2 0.0 1.3e-13 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORZ01234.1 - 4e-13 49.6 0.0 5.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORZ01234.1 - 4.5e-07 29.8 0.0 1e-06 28.6 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 ORZ01234.1 - 6.4e-07 29.4 0.0 8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORZ01234.1 - 1.7e-05 25.1 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORZ01234.1 - 0.0017 18.0 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase CRCB PF02537.15 ORZ01235.1 - 9.7e-32 109.2 20.3 4.2e-18 65.5 9.8 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) PrgI PF12666.7 ORZ01235.1 - 7.5 7.3 9.4 2.1 9.1 3.3 3.0 2 1 1 3 3 3 0 PrgI family protein Helicase_C_2 PF13307.6 ORZ01236.1 - 3.1e-54 183.7 0.0 9.1e-54 182.2 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ORZ01236.1 - 1.7e-51 174.4 0.3 3.3e-51 173.4 0.3 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 ORZ01236.1 - 2.1e-06 27.9 0.0 0.0062 16.6 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORZ01236.1 - 0.0014 18.9 0.1 0.074 13.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.23 ORZ01236.1 - 0.019 13.7 0.1 0.043 12.5 0.1 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain PhoH PF02562.16 ORZ01236.1 - 0.022 14.2 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Nefa_Nip30_N PF10187.9 ORZ01236.1 - 0.66 10.4 5.1 2.5 8.5 5.1 2.0 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 YlbD_coat PF14071.6 ORZ01236.1 - 1.7 8.9 5.7 5.4 7.3 0.4 3.3 3 0 0 3 3 3 0 Putative coat protein Pmp3 PF01679.17 ORZ01237.1 - 2.3e-19 69.3 11.2 2.8e-19 69.1 11.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Whi5 PF08528.11 ORZ01238.1 - 8e-09 34.9 0.0 1.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Whi5 like TFIIA PF03153.13 ORZ01238.1 - 0.044 13.8 18.5 0.055 13.5 18.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORZ01238.1 - 0.77 9.3 19.2 0.048 13.3 14.0 1.6 2 0 0 2 2 2 0 Spt20 family zf-CCHC PF00098.23 ORZ01239.1 - 1.2e-06 28.4 3.9 2.9e-06 27.1 2.1 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 ORZ01239.1 - 1.9e-05 24.5 0.1 4.1e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ORZ01239.1 - 2.3e-05 24.1 8.1 2.3e-05 24.1 8.1 2.3 2 0 0 2 2 2 1 Zinc knuckle zf_UBZ PF18439.1 ORZ01239.1 - 0.08 12.6 0.6 4.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Mss51 PF13824.6 ORZ01239.1 - 1.3 9.2 5.3 6.5 6.9 1.0 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C3HC4_2 PF13923.6 ORZ01239.1 - 1.4 8.9 8.7 0.14 12.0 2.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CLPTM1 PF05602.12 ORZ01241.1 - 4.1e-147 490.6 0.3 5.3e-147 490.3 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) 2TM PF13239.6 ORZ01241.1 - 0.022 15.1 2.3 0.022 15.1 2.3 2.1 2 0 0 2 2 2 0 2TM domain PQ-loop PF04193.14 ORZ01241.1 - 0.032 14.0 0.1 0.095 12.5 0.1 1.7 1 0 0 1 1 1 0 PQ loop repeat ABC_membrane_3 PF13748.6 ORZ01241.1 - 0.046 12.9 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region zf-C2H2 PF00096.26 ORZ01243.1 - 3.6e-18 64.9 39.2 4e-05 23.8 1.7 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ01243.1 - 1.2e-11 44.4 33.9 0.0017 19.0 1.0 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ01243.1 - 9.8e-08 32.5 21.8 0.011 16.3 2.1 4.8 3 1 1 4 4 4 4 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORZ01243.1 - 1.1e-07 32.0 14.7 2.8e-05 24.3 2.0 5.3 6 0 0 6 6 6 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORZ01243.1 - 0.015 15.0 18.8 0.27 11.0 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Ogr_Delta PF04606.12 ORZ01243.1 - 0.15 12.1 10.7 0.84 9.7 0.6 4.3 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_9 PF16293.5 ORZ01243.1 - 0.16 11.8 6.7 26 4.8 0.1 3.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 ORZ01243.1 - 0.21 11.7 0.3 0.21 11.7 0.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORZ01243.1 - 0.49 10.5 17.7 1.5 9.0 0.9 3.8 2 2 1 4 4 4 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORZ01243.1 - 1.5 9.2 15.0 8.6 6.8 1.0 4.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding M20_dimer PF07687.14 ORZ01244.1 - 2.3e-13 50.0 0.1 7.8e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORZ01244.1 - 8e-05 22.4 0.2 0.00017 21.4 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Pyr_redox PF00070.27 ORZ01244.1 - 0.031 14.8 0.0 6.6 7.4 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PBP1_TM PF14812.6 ORZ01245.1 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Ras PF00071.22 ORZ01247.1 - 1.5e-55 187.2 0.1 1.8e-55 186.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ01247.1 - 3.9e-18 65.8 0.0 6.8e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ01247.1 - 0.0002 20.9 0.0 0.00025 20.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORZ01247.1 - 0.00037 20.1 0.0 0.00056 19.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Fungal_trans PF04082.18 ORZ01248.1 - 6.8e-16 58.1 1.3 6.8e-16 58.1 1.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ribosomal_S7e PF01251.18 ORZ01249.1 - 5.5e-81 270.7 3.8 6.1e-81 270.6 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF3209 PF11483.8 ORZ01249.1 - 0.12 12.8 0.6 0.41 11.1 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) IF4E PF01652.18 ORZ01250.1 - 3.8e-55 186.0 1.7 4.9e-55 185.7 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S10 PF00338.22 ORZ01251.1 - 1.9e-28 98.6 0.7 2.3e-28 98.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2540 PF10802.8 ORZ01251.1 - 0.089 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Abhydrolase_3 PF07859.13 ORZ01252.1 - 2e-26 93.2 0.2 4.4e-26 92.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 ORZ01252.1 - 7.5e-22 77.9 0.1 5.6e-20 71.7 0.1 2.6 1 1 1 2 2 2 1 Carboxylesterase family LIP PF03583.14 ORZ01252.1 - 0.0011 18.4 0.0 0.41 9.9 0.0 2.9 3 0 0 3 3 3 2 Secretory lipase Hydrolase_4 PF12146.8 ORZ01252.1 - 0.0079 15.5 0.1 0.051 12.8 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORZ01252.1 - 0.0082 15.6 0.1 0.048 13.1 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 ORZ01252.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TFIIIC_delta PF12657.7 ORZ01252.1 - 0.068 13.1 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term APOBEC3 PF18771.1 ORZ01252.1 - 0.11 12.6 0.1 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 APOBEC3 DAGAT PF03982.13 ORZ01253.1 - 1e-99 333.2 0.0 1.2e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF4229 PF14012.6 ORZ01253.1 - 1.7 8.8 5.9 3.4 7.8 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) CSN8_PSD8_EIF3K PF10075.9 ORZ01255.1 - 2.5e-32 111.8 1.3 3.5e-32 111.4 1.3 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 ORZ01255.1 - 0.0023 17.4 0.6 0.003 17.0 0.6 1.3 1 0 0 1 1 1 1 SAC3/GANP family IPK PF03770.16 ORZ01256.1 - 1e-49 169.1 0.1 3.4e-49 167.4 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase CDP-OH_P_transf PF01066.21 ORZ01257.1 - 1.4e-12 48.1 0.4 1.4e-12 48.1 0.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MobB PF03205.14 ORZ01258.1 - 6.3e-05 22.9 0.0 0.0066 16.3 0.0 2.4 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 ORZ01258.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 ORZ01258.1 - 0.00022 20.9 0.1 0.00054 19.6 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORZ01258.1 - 0.00041 20.9 0.0 0.00093 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ01258.1 - 0.00067 20.1 0.0 0.0016 18.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.18 ORZ01258.1 - 0.00076 19.3 0.0 0.04 13.7 0.0 2.5 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 ORZ01258.1 - 0.0023 17.2 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 ORZ01258.1 - 0.0031 17.8 0.0 0.0083 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORZ01258.1 - 0.004 16.5 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 ORZ01258.1 - 0.0043 16.9 0.2 0.0078 16.0 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 ORZ01258.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 ORZ01258.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NCBP3 PF10309.9 ORZ01258.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 AAA_28 PF13521.6 ORZ01258.1 - 0.05 13.9 0.0 0.21 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ORZ01258.1 - 0.074 13.5 0.0 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORZ01258.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORZ01258.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.17 ORZ01258.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 ORZ01258.1 - 0.2 11.4 0.0 0.42 10.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORZ01258.1 - 0.2 12.1 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORZ01258.1 - 0.24 11.3 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 NTPase PWWP PF00855.17 ORZ01259.1 - 1.1e-16 61.0 0.8 4.3e-16 59.1 0.2 2.3 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 ORZ01259.1 - 5.3e-06 26.4 0.0 3.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain FPL PF09758.9 ORZ01259.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein Forkhead_N PF08430.12 ORZ01260.1 - 0.0032 18.1 1.1 0.0039 17.8 1.1 1.1 1 0 0 1 1 1 1 Forkhead N-terminal region Rhodanese_C PF12368.8 ORZ01261.1 - 3.8e-14 52.8 11.1 6.5e-14 52.1 11.1 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 ORZ01261.1 - 1.2e-10 41.8 0.0 1.9e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain TFA2_Winged_2 PF18121.1 ORZ01261.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 zinc_ribbon_5 PF13719.6 ORZ01261.1 - 2.3 8.0 7.2 21 5.0 2.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 ORZ01261.1 - 4.9 8.3 7.0 35 5.6 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger UFD1 PF03152.14 ORZ01262.1 - 4.1e-75 251.0 0.0 5.1e-75 250.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 ORZ01262.1 - 0.013 15.6 0.0 0.2 11.8 0.0 2.4 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Glyco_hydro_18 PF00704.28 ORZ01264.1 - 3.8e-19 69.6 0.8 1.6e-18 67.5 0.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Sulfotransfer_4 PF17784.1 ORZ01265.1 - 1.8e-61 207.7 0.0 2.1e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORZ01265.1 - 0.0087 16.5 0.0 0.45 10.9 0.0 2.4 2 1 1 3 3 3 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORZ01265.1 - 0.049 13.1 0.0 0.42 10.1 0.0 2.3 2 1 0 2 2 2 0 Sulfotransferase domain RAI16-like PF10257.9 ORZ01266.1 - 9.3e-76 255.0 1.9 1.3e-75 254.5 1.9 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF3808 PF10300.9 ORZ01267.1 - 4.9e-80 269.6 3.3 5.9e-79 266.0 3.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) DUF4516 PF14990.6 ORZ01268.1 - 3.2e-05 23.6 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) MctB PF11382.8 ORZ01268.1 - 0.048 13.4 0.0 0.054 13.2 0.0 1.0 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB B12D PF06522.11 ORZ01268.1 - 0.17 11.7 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ribosomal_60s PF00428.19 ORZ01269.1 - 0.25 11.9 6.3 0.66 10.6 6.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TUSC2 PF15000.6 ORZ01269.1 - 3 8.2 12.9 8.7 6.7 4.6 2.6 2 1 0 2 2 2 0 Tumour suppressor candidate 2 WBP-1 PF11669.8 ORZ01271.1 - 0.0039 17.8 2.6 0.013 16.2 0.1 2.3 2 0 0 2 2 2 1 WW domain-binding protein 1 7TM_GPCR_Srv PF10323.9 ORZ01271.1 - 0.092 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Comm PF15957.5 ORZ01271.1 - 0.25 11.7 1.9 0.45 10.9 1.3 1.8 1 1 0 1 1 1 0 Commissureless UPF0052 PF01933.18 ORZ01272.1 - 3.3e-47 161.1 0.0 4.7e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 ATP-synt_DE_N PF02823.16 ORZ01274.1 - 2e-17 62.8 0.1 2.9e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain EF-hand_1 PF00036.32 ORZ01275.1 - 1.1e-26 90.4 8.9 6.7e-10 37.8 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 ORZ01275.1 - 1.3e-23 83.2 10.2 8.1e-17 61.4 1.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORZ01275.1 - 5.2e-19 66.5 8.2 1.5e-06 27.7 0.1 4.9 3 2 2 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 ORZ01275.1 - 7.8e-17 59.9 17.3 9.4e-08 31.2 0.9 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 ORZ01275.1 - 6.7e-16 57.9 7.5 3e-09 36.6 0.4 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 ORZ01275.1 - 4.3e-09 36.3 3.4 6.7e-05 22.8 0.5 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 ORZ01275.1 - 4.6e-07 29.9 4.9 0.035 14.3 0.4 3.9 3 1 1 4 4 4 3 Dockerin type I domain EF-hand_9 PF14658.6 ORZ01275.1 - 4e-06 27.0 0.4 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 ORZ01275.1 - 1.4e-05 25.4 2.0 0.00037 20.8 0.1 2.4 1 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 ORZ01275.1 - 0.00042 20.3 4.7 0.089 12.8 0.2 2.8 2 1 1 3 3 3 2 Tellurite resistance protein TerB EF-hand_10 PF14788.6 ORZ01275.1 - 0.0035 17.2 3.3 6.2 6.8 0.1 3.4 3 0 0 3 3 3 2 EF hand DUF1456 PF07308.13 ORZ01275.1 - 0.048 14.0 0.5 0.68 10.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) DUF2666 PF10869.8 ORZ01275.1 - 0.061 13.5 0.3 5.5 7.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF1707 PF08044.11 ORZ01275.1 - 0.073 13.2 1.0 2.9 8.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) FGAR-AT_linker PF18072.1 ORZ01275.1 - 0.13 12.8 0.3 10 6.8 0.0 2.7 2 1 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_1 PF00036.32 ORZ01276.1 - 1.3e-27 93.2 7.6 5.3e-08 31.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORZ01276.1 - 5.9e-24 84.3 3.5 1.5e-13 51.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORZ01276.1 - 2.4e-23 80.0 4.9 1.4e-07 30.8 0.1 4.6 3 1 2 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 ORZ01276.1 - 3.1e-22 77.0 9.0 1.2e-07 30.9 0.2 4.6 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 ORZ01276.1 - 6.9e-21 73.8 8.5 3.8e-07 29.8 0.2 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 ORZ01276.1 - 1.7e-07 31.2 0.7 0.0036 17.2 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORZ01276.1 - 5.2e-07 29.9 0.0 0.036 14.4 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 ORZ01276.1 - 2.5e-06 27.8 0.1 0.028 14.7 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 ORZ01276.1 - 9.7e-05 22.4 1.1 0.073 13.0 0.1 3.0 2 1 1 3 3 3 2 Caleosin related protein Dockerin_1 PF00404.18 ORZ01276.1 - 0.003 17.7 0.0 0.28 11.4 0.0 2.7 2 1 1 3 3 3 1 Dockerin type I domain DUF2666 PF10869.8 ORZ01276.1 - 0.02 15.1 0.3 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) TerB PF05099.13 ORZ01276.1 - 0.021 14.8 0.1 1.6 8.7 0.0 2.2 1 1 2 3 3 3 0 Tellurite resistance protein TerB Toprim_2 PF13155.6 ORZ01276.1 - 0.025 15.0 1.2 0.83 10.1 0.0 2.6 1 1 0 2 2 2 0 Toprim-like T2SSF PF00482.23 ORZ01276.1 - 0.17 11.8 0.2 1.1 9.2 0.1 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Excalibur PF05901.11 ORZ01276.1 - 0.69 10.6 2.2 47 4.7 0.1 3.1 3 0 0 3 3 3 0 Excalibur calcium-binding domain Ribosomal_S5 PF00333.20 ORZ01278.1 - 8.8e-30 102.5 2.1 1.4e-29 101.8 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORZ01278.1 - 1e-24 85.7 0.1 1.7e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORZ01278.1 - 0.084 13.4 11.9 0.18 12.4 11.9 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RasGEF PF00617.19 ORZ01282.1 - 2.3e-49 168.0 0.1 4.8e-49 166.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORZ01282.1 - 7.4e-16 58.3 1.3 2.5e-15 56.6 1.3 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif PPP4R2 PF09184.11 ORZ01282.1 - 0.63 9.6 10.8 1.8 8.1 10.8 1.8 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 ORZ01282.1 - 1.5 8.5 18.8 2.9 7.5 18.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 ORZ01282.1 - 6.7 5.9 14.3 13 5.0 14.3 1.4 1 0 0 1 1 1 0 NOA36 protein Aa_trans PF01490.18 ORZ01283.1 - 5.4e-50 170.3 23.0 5.4e-50 170.3 23.0 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.22 ORZ01284.1 - 3.4e-18 65.2 0.4 3.4e-14 52.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ01284.1 - 0.035 14.2 0.0 6.9 6.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif NAD_binding_5 PF07994.12 ORZ01285.1 - 1.4e-146 487.9 0.0 1.7e-146 487.7 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ORZ01285.1 - 2.8e-44 149.8 0.1 5.2e-44 149.0 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF410 PF04190.13 ORZ01286.1 - 1.1e-71 241.6 0.1 1.4e-71 241.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) CRISPR_Cse2 PF09485.10 ORZ01286.1 - 0.11 13.0 0.4 9.1 6.8 0.1 2.4 2 1 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_2 PF07719.17 ORZ01286.1 - 0.22 11.7 2.0 13 6.2 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DNA_mis_repair PF01119.19 ORZ01287.1 - 9.5e-15 54.3 0.1 1.5e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Neurochondrin PF05536.11 ORZ01289.1 - 5.2e-54 183.7 5.4 6e-54 183.5 5.4 1.0 1 0 0 1 1 1 1 Neurochondrin Utp12 PF04003.12 ORZ01289.1 - 0.028 14.7 1.6 1 9.7 0.0 3.3 3 1 0 3 3 3 0 Dip2/Utp12 Family DUF4508 PF14969.6 ORZ01289.1 - 0.045 14.0 0.8 6.9 7.0 0.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4508) DUF599 PF04654.12 ORZ01289.1 - 0.059 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Xpo1 PF08389.12 ORZ01289.1 - 0.1 12.7 6.0 3.3 7.8 0.3 4.1 3 2 1 4 4 4 0 Exportin 1-like protein MOR2-PAG1_C PF14225.6 ORZ01289.1 - 0.13 12.1 8.3 1.8 8.3 0.6 3.9 3 1 1 5 5 5 0 Cell morphogenesis C-terminal Ribonuc_2-5A PF06479.12 ORZ01289.1 - 0.14 12.4 2.7 2.3 8.4 0.2 3.0 2 1 0 2 2 2 0 Ribonuclease 2-5A p450 PF00067.22 ORZ01290.1 - 1.5e-84 284.4 0.0 2e-84 284.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3_C PF01915.22 ORZ01291.1 - 5.7e-59 199.5 0.0 1.1e-58 198.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORZ01291.1 - 2.3e-43 148.8 0.1 7.7e-43 147.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORZ01291.1 - 4.5e-22 77.9 0.0 1.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 ORZ01292.1 - 1.6e-60 204.6 0.0 3.1e-60 203.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORZ01292.1 - 2.3e-38 132.4 0.0 3.7e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORZ01292.1 - 4.8e-21 74.7 0.1 9.8e-21 73.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 ORZ01293.1 - 7.3e-62 209.0 0.0 1.1e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORZ01293.1 - 8e-39 133.9 0.0 1.3e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORZ01293.1 - 8.7e-23 80.2 0.0 1.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MoCF_biosynth PF00994.24 ORZ01296.1 - 2.3e-28 98.6 0.0 1.4e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain ACT_6 PF13740.6 ORZ01296.1 - 0.03 14.3 0.1 20 5.3 0.0 3.3 4 0 0 4 4 4 0 ACT domain Fungal_trans PF04082.18 ORZ01297.1 - 2.7e-24 85.7 0.0 4.3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORZ01297.1 - 1.8e-09 37.6 12.7 3.8e-09 36.5 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ING PF12998.7 ORZ01297.1 - 0.081 13.5 0.2 0.41 11.3 0.0 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding EXS PF03124.14 ORZ01298.1 - 9.4e-73 245.4 30.2 1.1e-72 245.2 30.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 ORZ01299.1 - 2.1e-16 60.8 3.5 5.6e-16 59.4 3.5 1.6 1 1 0 1 1 1 1 SPX domain RNB PF00773.19 ORZ01300.1 - 3.6e-93 312.5 0.1 5.1e-93 312.0 0.1 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORZ01300.1 - 9.4e-19 67.2 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 ORZ01300.1 - 5e-09 36.2 0.6 6e-05 23.1 0.2 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 ORZ01300.1 - 3.1e-07 30.2 0.0 7.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 ORZ01300.1 - 0.00099 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 S1 domain Lsm_C PF14894.6 ORZ01300.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.8 1 0 0 1 1 1 0 Lsm C-terminal LRR_6 PF13516.6 ORZ01302.1 - 5.4e-09 35.4 5.4 1.6 9.0 0.0 6.4 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 ORZ01302.1 - 4.8e-07 30.0 4.3 0.18 12.3 0.0 5.4 3 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORZ01302.1 - 8.6e-06 25.4 3.5 0.0075 16.0 0.0 4.3 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 ORZ01302.1 - 0.0004 20.6 8.7 18 6.4 0.0 6.0 7 0 0 7 7 7 3 Leucine Rich Repeat Sugar_tr PF00083.24 ORZ01303.1 - 9.1e-108 361.0 26.8 1.1e-107 360.8 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ01303.1 - 5.3e-34 117.7 22.7 5.3e-34 117.7 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 ORZ01303.1 - 7.9e-05 21.6 2.9 0.00013 20.9 2.5 1.6 1 1 0 1 1 1 1 Reduced folate carrier MFS_2 PF13347.6 ORZ01303.1 - 0.11 11.1 33.2 0.034 12.7 11.3 3.3 3 1 0 3 3 3 0 MFS/sugar transport protein FSH1 PF03959.13 ORZ01304.1 - 3.3e-61 206.6 0.0 3.7e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 ORZ01304.1 - 0.016 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2235 PF09994.9 ORZ01304.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.16 ORZ01304.1 - 0.16 11.7 0.4 1.6 8.5 0.4 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_6 PF13344.6 ORZ01305.1 - 5.8e-21 74.5 0.0 1.1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORZ01305.1 - 1.4e-15 57.1 0.0 3.3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORZ01305.1 - 2.3e-05 24.8 0.0 0.036 14.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORZ01305.1 - 0.00014 22.0 0.0 0.065 13.3 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase IMS PF00817.20 ORZ01306.1 - 6.1e-47 159.4 0.1 6.1e-47 159.4 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ORZ01306.1 - 2.1e-14 54.2 0.9 1.1e-13 52.0 0.9 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ORZ01306.1 - 0.00021 21.4 0.0 0.00054 20.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-CpG_bind_C PF12269.8 ORZ01306.1 - 0.16 11.8 3.9 0.094 12.5 0.9 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain TRAF6_Z2 PF18048.1 ORZ01306.1 - 0.33 11.1 1.7 1 9.5 0.2 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Sec7 PF01369.20 ORZ01307.1 - 2.6e-26 92.4 0.2 4.4e-26 91.7 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORZ01307.1 - 2.5e-07 31.1 0.0 6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Sel1 PF08238.12 ORZ01308.1 - 5.8e-37 125.3 31.3 1.6e-07 31.8 0.0 13.4 14 0 0 14 14 14 8 Sel1 repeat TPR_6 PF13174.6 ORZ01308.1 - 0.00011 22.6 5.7 6.3 7.7 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ01308.1 - 0.0095 15.9 2.2 3.4 7.9 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.24 ORZ01309.1 - 2.9e-18 65.3 40.8 3e-05 23.8 0.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORZ01309.1 - 7.2e-16 58.8 31.9 0.00017 22.3 0.5 5.4 1 1 4 5 5 5 5 Torus domain zf_CCCH_4 PF18345.1 ORZ01309.1 - 2.4e-12 46.5 60.7 2.2e-05 24.4 3.1 5.6 6 0 0 6 6 6 5 Zinc finger domain zf-CCHC PF00098.23 ORZ01309.1 - 1.6e-06 27.9 3.6 1.6e-06 27.9 3.6 2.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_4 PF18044.1 ORZ01309.1 - 1.7e-06 27.6 45.6 4.8e-05 23.0 0.6 5.4 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 ORZ01309.1 - 4.1e-06 27.0 4.7 4.1e-06 27.0 4.7 3.3 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORZ01309.1 - 0.02 15.4 48.1 0.037 14.5 4.1 6.0 7 0 0 7 7 7 0 RNA-binding, Nab2-type zinc finger Methyltransf_16 PF10294.9 ORZ01310.1 - 3.5e-23 82.2 1.3 3.9e-14 52.8 0.1 2.2 1 1 1 2 2 2 2 Lysine methyltransferase GidB PF02527.15 ORZ01310.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Stk19 PF10494.9 ORZ01311.1 - 2.2e-25 89.8 0.1 4.1e-25 88.9 0.1 1.4 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 PEP-utilisers_N PF05524.13 ORZ01311.1 - 0.2 11.8 1.8 6.5 7.0 0.3 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Bromodomain PF00439.25 ORZ01312.1 - 2e-44 149.6 0.0 6.7e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 Bromodomain RNA_pol_I_A49 PF06870.12 ORZ01312.1 - 0.0038 16.1 0.4 0.0057 15.6 0.4 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF2721 PF11026.8 ORZ01312.1 - 0.4 10.6 1.6 0.75 9.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) UDPGP PF01704.18 ORZ01314.1 - 1.3e-200 666.4 0.2 1.5e-200 666.1 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ENTH PF01417.20 ORZ01316.1 - 1.5e-46 157.5 1.4 2.2e-46 157.0 1.4 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ORZ01316.1 - 7.3e-06 25.2 0.2 1e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 ANTH domain Biopterin_H PF00351.21 ORZ01316.1 - 0.1 11.6 0.4 0.16 11.0 0.4 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase SUIM_assoc PF16619.5 ORZ01316.1 - 3.1 7.9 11.6 0.6 10.2 4.4 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF5320 PF17253.2 ORZ01316.1 - 8 7.6 13.1 1.4 10.1 8.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Aldo_ket_red PF00248.21 ORZ01317.1 - 1.2e-52 179.0 0.0 7.1e-51 173.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CKAP2_C PF15297.6 ORZ01319.1 - 0.041 13.0 0.4 0.067 12.3 0.4 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus NBD_C PF17042.5 ORZ01319.1 - 0.26 11.8 1.5 0.37 11.3 1.5 1.2 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DUF4149 PF13664.6 ORZ01320.1 - 0.032 14.6 0.4 0.046 14.0 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) MTHFR PF02219.17 ORZ01321.1 - 3.7e-113 377.6 0.0 5.5e-113 377.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HMG_box PF00505.19 ORZ01322.1 - 2.4e-24 85.5 1.2 2.4e-24 85.5 1.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ01322.1 - 1.1e-15 57.9 1.1 2e-15 57.1 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 ORZ01322.1 - 0.0013 18.6 0.3 0.0029 17.6 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 ORZ01322.1 - 0.029 14.3 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain Ribosomal_S25 PF03297.15 ORZ01322.1 - 1.1 9.5 7.2 0.18 12.0 3.2 1.7 1 1 1 2 2 2 0 S25 ribosomal protein HVSL PF09749.9 ORZ01323.1 - 1.8e-42 145.5 0.1 2.2e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 ORZ01323.1 - 0.00033 20.6 0.3 0.00099 19.0 0.2 1.7 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily Chitin_synth_2 PF03142.15 ORZ01324.1 - 6.9e-240 797.1 1.4 1e-239 796.6 1.4 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORZ01324.1 - 1.2e-14 54.8 0.1 3.3e-14 53.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORZ01324.1 - 3.2e-13 50.1 3.6 9.2e-13 48.6 3.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORZ01324.1 - 4.1e-05 23.1 0.3 0.00032 20.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORZ01324.1 - 0.037 13.8 0.0 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 CBS PF00571.28 ORZ01325.1 - 1.6e-11 44.5 0.0 3.8e-05 24.0 0.0 2.9 3 0 0 3 3 3 2 CBS domain Chitin_synth_1 PF01644.17 ORZ01326.1 - 4.9e-76 254.2 0.0 7.4e-76 253.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORZ01326.1 - 7.9e-27 93.0 0.1 1.6e-25 88.8 0.2 2.4 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORZ01326.1 - 1.3e-21 76.8 2.0 6e-18 64.7 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORZ01326.1 - 1.2e-10 41.6 4.9 1.2e-10 41.6 4.9 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORZ01326.1 - 5.8e-06 26.4 0.0 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF1516 PF07457.11 ORZ01326.1 - 0.041 14.1 3.9 0.13 12.4 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF21 PF01595.20 ORZ01327.1 - 3.2e-33 114.9 1.0 5.6e-33 114.1 1.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORZ01327.1 - 2.5e-11 43.8 0.5 8.5e-07 29.3 0.3 2.6 2 0 0 2 2 2 2 CBS domain UPF0270 PF06794.12 ORZ01327.1 - 0.047 13.8 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) UBA PF00627.31 ORZ01328.1 - 3.6e-05 23.6 0.0 8.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rrn6 PF10214.9 ORZ01328.1 - 0.15 10.6 4.2 0.15 10.5 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3583 PF12126.8 ORZ01328.1 - 2.8 7.3 7.8 5.5 6.3 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) E1-E2_ATPase PF00122.20 ORZ01329.1 - 3.8e-53 179.7 0.0 3.8e-53 179.7 0.0 3.2 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORZ01329.1 - 6.9e-48 162.8 3.8 6.9e-48 162.8 3.8 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORZ01329.1 - 3.7e-22 79.6 2.0 5.3e-21 75.9 2.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORZ01329.1 - 8.9e-16 57.8 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORZ01329.1 - 1.5e-15 56.6 0.1 3.2e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ01329.1 - 6.8e-05 22.7 2.7 0.0007 19.4 1.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORZ01329.1 - 0.0079 16.6 0.0 0.027 14.9 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 ORZ01329.1 - 0.058 13.6 0.1 0.058 13.6 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) DUF2127 PF09900.9 ORZ01329.1 - 0.57 10.4 6.0 0.2 11.9 1.0 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) MFS_1 PF07690.16 ORZ01331.1 - 5.2e-18 65.1 30.8 3.2e-14 52.6 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Med30 PF11315.8 ORZ01333.1 - 0.08 13.1 1.6 1.4 9.1 1.6 2.2 1 1 0 1 1 1 0 Mediator complex subunit 30 FapA PF03961.13 ORZ01333.1 - 0.32 9.5 0.0 0.43 9.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 ORZ01333.1 - 0.35 11.3 6.5 1.7 9.1 2.3 2.5 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.24 ORZ01333.1 - 0.95 9.4 3.0 3 7.8 3.0 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CKS PF01111.19 ORZ01334.1 - 1.9e-24 85.7 0.7 3e-24 85.1 0.7 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ndc1_Nup PF09531.10 ORZ01334.1 - 0.28 9.8 0.8 0.24 10.0 0.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 ORZ01334.1 - 1.1 7.9 5.1 1.7 7.4 5.1 1.2 1 0 0 1 1 1 0 Presenilin MFS_5 PF05631.14 ORZ01335.1 - 3e-75 253.4 10.0 3.9e-75 253.0 10.0 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ORZ01335.1 - 7e-17 61.4 47.2 3.1e-13 49.4 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORZ01335.1 - 0.0016 17.4 12.6 0.081 11.8 0.1 2.6 1 1 1 2 2 2 2 MFS_1 like family NodZ PF05830.11 ORZ01335.1 - 0.034 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) MFS_2 PF13347.6 ORZ01335.1 - 1.3 7.5 30.4 0.014 14.0 4.4 3.1 2 1 1 3 3 3 0 MFS/sugar transport protein SpoVAB PF13782.6 ORZ01335.1 - 9.9 6.5 14.6 3.5 8.0 0.8 3.6 2 2 0 4 4 4 0 Stage V sporulation protein AB MMtag PF10159.9 ORZ01336.1 - 4.4e-32 110.2 1.6 4.4e-32 110.2 1.6 3.1 3 1 0 3 3 3 1 Multiple myeloma tumor-associated WH1 PF00568.23 ORZ01337.1 - 3.2e-21 75.4 0.0 4.7e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 ORZ01337.1 - 2.1e-07 31.2 0.2 4.5e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 ORZ01337.1 - 0.00025 20.8 0.7 0.00047 19.9 0.7 1.5 1 0 0 1 1 1 1 WH2 motif ORMDL PF04061.14 ORZ01338.1 - 8.4e-37 126.0 0.4 9.4e-37 125.9 0.4 1.0 1 0 0 1 1 1 1 ORMDL family WD40 PF00400.32 ORZ01339.1 - 1.8e-15 57.1 12.3 3.8e-05 24.4 0.5 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01339.1 - 7.8e-14 51.7 0.5 0.00019 21.6 0.1 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 ORZ01339.1 - 0.0065 15.6 1.0 1.4 7.8 0.0 3.1 2 1 0 2 2 2 2 Coatomer WD associated region PilM PF07419.12 ORZ01339.1 - 0.22 11.7 0.2 11 6.2 0.1 2.8 3 0 0 3 3 3 0 PilM zf-C2H2 PF00096.26 ORZ01340.1 - 2.2e-13 49.8 11.9 3.9e-07 30.2 3.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ01340.1 - 3.5e-10 39.8 9.9 2.6e-05 24.7 2.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORZ01340.1 - 1.5e-09 37.8 16.2 1e-08 35.2 1.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ01340.1 - 2.4e-05 24.2 6.7 0.00039 20.3 1.4 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORZ01340.1 - 0.0018 18.5 0.9 0.28 11.5 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 ORZ01340.1 - 0.0053 16.6 8.5 0.094 12.6 1.8 2.2 1 1 1 2 2 2 2 SprT-like zinc ribbon domain zf-met PF12874.7 ORZ01340.1 - 0.0068 16.8 2.2 0.28 11.7 0.2 2.5 2 1 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORZ01340.1 - 0.04 14.0 2.8 0.49 10.6 0.8 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_aberr PF17017.5 ORZ01340.1 - 0.075 13.2 0.3 0.075 13.2 0.3 1.5 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 ORZ01340.1 - 0.13 12.0 8.0 2.1 8.2 0.4 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type MCM_OB PF17207.3 ORZ01340.1 - 0.14 12.0 0.8 0.15 12.0 0.8 1.1 1 0 0 1 1 1 0 MCM OB domain zinc_ribbon_9 PF14369.6 ORZ01340.1 - 0.35 11.2 5.9 3.1 8.2 5.2 2.4 1 1 1 2 2 2 0 zinc-ribbon zf-H2C2_5 PF13909.6 ORZ01340.1 - 2.4 8.0 19.6 10 6.0 6.6 3.5 2 2 0 2 2 2 0 C2H2-type zinc-finger domain PQ-loop PF04193.14 ORZ01341.1 - 2.7e-37 126.3 13.2 5.5e-19 67.7 0.4 2.9 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 ORZ01341.1 - 8.8e-05 23.4 1.8 0.00021 22.1 1.8 1.7 1 1 0 1 1 1 1 ER lumen protein retaining receptor NMN_transporter PF04973.12 ORZ01341.1 - 0.33 10.9 12.3 1.9 8.5 0.2 3.3 3 1 0 3 3 3 0 Nicotinamide mononucleotide transporter MtN3_slv PF03083.16 ORZ01341.1 - 2.9 8.0 10.2 0.08 13.0 1.5 2.8 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Y_phosphatase PF00102.27 ORZ01342.1 - 2.3e-07 30.6 0.0 6.2e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORZ01342.1 - 1.2e-06 28.3 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4817 PF16087.5 ORZ01342.1 - 0.094 12.5 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Tub PF01167.18 ORZ01344.1 - 3.7e-78 262.6 0.1 4.3e-78 262.4 0.1 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 ORZ01344.1 - 0.029 14.0 0.2 1 8.9 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3527) DUF3579 PF12112.8 ORZ01344.1 - 0.061 13.9 0.0 2.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) BAR PF03114.18 ORZ01345.1 - 5.1e-27 95.1 3.4 7.7e-27 94.5 3.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORZ01345.1 - 7.1e-17 60.7 0.1 1.7e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORZ01345.1 - 1.4e-13 50.5 0.1 2.6e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORZ01345.1 - 4.9e-11 42.2 0.0 1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 ORZ01345.1 - 0.0028 17.2 1.5 0.0062 16.1 1.5 1.5 1 0 0 1 1 1 1 Vps5 C terminal like FAM76 PF16046.5 ORZ01345.1 - 0.015 14.7 0.9 0.015 14.7 0.9 1.6 2 0 0 2 2 2 0 FAM76 protein APG6_N PF17675.1 ORZ01345.1 - 0.057 13.9 0.9 0.057 13.9 0.9 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region E2R135 PF11570.8 ORZ01345.1 - 0.079 13.2 0.4 0.079 13.2 0.4 2.6 2 2 1 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 Pkinase PF00069.25 ORZ01346.1 - 2.9e-51 174.4 0.0 3.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01346.1 - 1.1e-34 120.0 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ01346.1 - 0.00026 19.9 0.0 0.00038 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORZ01346.1 - 0.0068 15.8 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORZ01346.1 - 0.029 14.3 0.1 0.049 13.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 ORZ01347.1 - 1.2e-60 203.7 0.7 1.5e-60 203.5 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ01347.1 - 1.5e-35 122.0 0.3 2.1e-35 121.5 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ01347.1 - 6.3e-14 51.8 0.1 7.9e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORZ01347.1 - 9.7e-06 25.7 0.1 1.7e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORZ01347.1 - 6.5e-05 22.5 0.2 0.0003 20.4 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORZ01347.1 - 9e-05 21.9 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORZ01347.1 - 0.00025 21.0 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ORZ01347.1 - 0.0065 16.7 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 ORZ01347.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORZ01347.1 - 0.02 15.3 0.1 0.033 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 ORZ01347.1 - 0.028 13.6 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 ORZ01347.1 - 0.034 14.7 0.4 0.052 14.1 0.4 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORZ01347.1 - 0.036 13.8 0.1 0.063 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORZ01347.1 - 0.066 13.2 0.3 0.29 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORZ01347.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORZ01347.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region zf-C5HC2 PF02928.16 ORZ01348.1 - 0.02 15.3 1.2 2 8.8 0.2 2.3 2 0 0 2 2 2 0 C5HC2 zinc finger FYVE_2 PF02318.16 ORZ01348.1 - 0.1 12.8 1.2 0.68 10.2 0.5 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger Lipase_GDSL PF00657.22 ORZ01349.1 - 9.6e-06 25.7 0.0 1.3e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORZ01349.1 - 0.0016 18.8 0.0 0.0022 18.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORZ01350.1 - 1.1e-13 51.7 0.0 2.4e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORZ01350.1 - 1.3e-05 25.7 0.2 0.00035 21.0 0.2 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cullin PF00888.22 ORZ01351.1 - 1.5e-20 73.4 3.9 1.5e-20 73.4 3.9 2.4 1 1 1 3 3 3 1 Cullin family DUF913 PF06025.12 ORZ01351.1 - 0.0064 15.5 0.0 0.019 14.0 0.1 1.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) Agglutinin PF07468.11 ORZ01351.1 - 0.016 15.4 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Agglutinin domain Chitin_synth_2 PF03142.15 ORZ01352.1 - 2.7e-280 930.5 0.0 3.6e-280 930.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORZ01352.1 - 4e-13 49.8 0.0 1.6e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORZ01352.1 - 1.1e-12 48.3 1.3 3.6e-12 46.6 1.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORZ01352.1 - 6.9e-05 22.7 0.0 0.0053 16.6 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORZ01352.1 - 0.003 17.0 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF5549 PF17703.1 ORZ01352.1 - 0.079 12.6 1.5 0.18 11.5 1.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5549) CBF PF03914.17 ORZ01353.1 - 2.9e-58 196.6 4.0 1.5e-56 191.1 0.1 2.6 2 0 0 2 2 2 2 CBF/Mak21 family Connexin PF00029.19 ORZ01353.1 - 0.0047 16.7 3.3 2 8.1 0.0 3.2 3 0 0 3 3 3 2 Connexin Cnd1 PF12717.7 ORZ01353.1 - 0.14 12.2 2.8 0.37 10.8 0.5 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 U1snRNP70_N PF12220.8 ORZ01353.1 - 1.7 9.3 9.9 22 5.7 0.1 3.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DEAD PF00270.29 ORZ01354.1 - 1.6e-47 161.5 0.0 3.3e-47 160.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ01354.1 - 1.2e-26 93.3 1.5 7.5e-26 90.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORZ01354.1 - 4.3e-19 68.5 1.5 1e-18 67.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORZ01354.1 - 6.7e-09 36.0 1.5 5.9e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HAD_2 PF13419.6 ORZ01356.1 - 8.1e-08 32.5 0.0 1.3e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORZ01356.1 - 2.6e-07 31.1 0.0 4.1e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORZ01356.1 - 8.5e-06 25.7 0.0 2.9e-05 24.0 0.0 1.9 3 0 0 3 3 3 1 HAD-hyrolase-like Phosphoesterase PF04185.14 ORZ01357.1 - 3.6e-30 105.4 7.2 3.6e-30 105.3 2.7 2.6 1 1 1 2 2 2 1 Phosphoesterase family Cpn60_TCP1 PF00118.24 ORZ01358.1 - 6.6e-152 506.6 18.4 7.5e-152 506.4 18.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 ORZ01358.1 - 0.0021 17.6 0.2 0.0056 16.2 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination DUF3425 PF11905.8 ORZ01359.1 - 2.9e-08 33.7 1.3 5.9e-08 32.7 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) DUF2722 PF10846.8 ORZ01359.1 - 0.0014 17.7 8.9 0.0014 17.7 8.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Ebola_NP PF05505.12 ORZ01359.1 - 0.0077 14.6 2.7 0.012 14.0 2.7 1.2 1 0 0 1 1 1 1 Ebola nucleoprotein DUF572 PF04502.13 ORZ01359.1 - 0.0096 15.6 4.6 0.016 14.8 4.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 ORZ01359.1 - 0.048 13.2 9.2 0.88 9.1 2.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit FAM83 PF07894.12 ORZ01359.1 - 0.05 13.1 1.7 0.079 12.5 1.7 1.2 1 0 0 1 1 1 0 FAM83 A-H CPSF100_C PF13299.6 ORZ01359.1 - 0.11 12.6 3.6 0.81 9.8 1.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CCDC53 PF10152.9 ORZ01359.1 - 0.36 11.2 8.8 1.6 9.1 4.2 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FAM70 PF14967.6 ORZ01359.1 - 0.37 10.2 1.3 0.56 9.6 1.3 1.2 1 0 0 1 1 1 0 FAM70 protein Neur_chan_memb PF02932.16 ORZ01359.1 - 0.95 9.5 7.1 2.7 8.0 1.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hydin_ADK PF17213.3 ORZ01359.1 - 1.5 9.1 5.6 0.49 10.6 2.5 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Eapp_C PF10238.9 ORZ01359.1 - 1.8 8.7 8.0 0.42 10.7 1.6 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Connexin PF00029.19 ORZ01359.1 - 3.5 7.3 7.0 15 5.3 2.2 2.1 2 0 0 2 2 2 0 Connexin DDHD PF02862.17 ORZ01359.1 - 4.2 7.5 8.8 11 6.1 8.7 1.7 1 1 0 1 1 1 0 DDHD domain GvpL_GvpF PF06386.11 ORZ01359.1 - 5.5 6.8 13.0 2.2 8.2 4.2 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF RPA43_OB PF17875.1 ORZ01359.1 - 6.1 7.5 9.6 0.79 10.4 3.1 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4820 PF16091.5 ORZ01359.1 - 6.4 6.1 12.0 0.078 12.3 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RIC3 PF15361.6 ORZ01359.1 - 7.1 7.0 10.0 8.2 6.8 2.0 2.4 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Spt20 PF12090.8 ORZ01359.1 - 7.4 6.1 24.2 0.084 12.5 16.1 1.7 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 ORZ01359.1 - 8.4 7.4 13.1 0.67 10.9 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ribosomal_L5e PF17144.4 ORZ01360.1 - 1.5e-84 282.0 0.4 3.4e-84 280.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORZ01360.1 - 3.6e-33 114.4 7.6 3.6e-33 114.4 7.6 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HGTP_anticodon2 PF12745.7 ORZ01360.1 - 0.08 12.4 1.9 0.12 11.8 1.9 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs HSP70 PF00012.20 ORZ01360.1 - 5.2 5.1 7.6 6.6 4.8 7.6 1.1 1 0 0 1 1 1 0 Hsp70 protein Pkinase PF00069.25 ORZ01362.1 - 2e-75 253.6 0.0 5.6e-75 252.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01362.1 - 2.2e-35 122.2 0.0 5.2e-35 121.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ01362.1 - 6.3e-06 25.7 0.5 0.12 11.7 0.0 3.2 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 ORZ01362.1 - 0.0062 16.5 0.1 0.22 11.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORZ01362.1 - 0.027 13.2 1.7 0.069 11.9 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase Glyco_hydro_15 PF00723.21 ORZ01363.1 - 2.1e-58 198.2 0.0 2.7e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 LapA_dom PF06305.11 ORZ01364.1 - 0.13 12.1 2.1 0.21 11.4 2.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain YrhK PF14145.6 ORZ01365.1 - 0.0026 17.6 0.8 3.2 7.7 0.2 2.6 2 0 0 2 2 2 2 YrhK-like protein Tmemb_40 PF10160.9 ORZ01365.1 - 0.0027 17.2 0.9 0.0069 15.9 0.9 1.7 1 0 0 1 1 1 1 Predicted membrane protein Nop PF01798.18 ORZ01366.1 - 1.3e-89 299.6 0.0 1.3e-89 299.6 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORZ01366.1 - 2.4e-20 72.6 0.4 2.4e-20 72.6 0.4 2.9 3 1 0 3 3 3 1 NOP5NT (NUC127) domain PPP4R2 PF09184.11 ORZ01366.1 - 1.5 8.4 29.0 0.24 10.9 25.3 1.5 2 0 0 2 2 2 0 PPP4R2 VIR_N PF15912.5 ORZ01366.1 - 7.6 6.0 19.4 12 5.4 19.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CBFD_NFYB_HMF PF00808.23 ORZ01367.1 - 2.6e-18 66.1 0.5 4.8e-18 65.2 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORZ01367.1 - 0.01 16.2 0.7 0.06 13.7 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 ORZ01367.1 - 0.035 14.3 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 CENP-W protein Suc_Fer-like PF06999.12 ORZ01368.1 - 1.2e-40 139.5 0.0 1.5e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Sec2p PF06428.11 ORZ01369.1 - 1.9e-23 82.2 33.0 2.7e-23 81.8 18.3 2.5 1 1 1 2 2 2 2 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 ORZ01369.1 - 0.0057 16.9 13.4 0.0057 16.9 13.4 2.8 1 1 1 2 2 1 1 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 ORZ01369.1 - 0.29 9.0 24.4 0.017 13.1 15.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 ORZ01369.1 - 0.37 11.2 24.6 0.67 10.4 24.6 1.4 1 0 0 1 1 1 0 Fez1 DUF1664 PF07889.12 ORZ01369.1 - 0.48 10.5 14.9 0.099 12.7 1.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 ORZ01369.1 - 0.5 10.5 17.0 2.1 8.6 4.6 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 ORZ01369.1 - 0.57 9.5 32.5 0.016 14.6 7.8 2.1 1 1 1 2 2 2 0 Tropomyosin Filament PF00038.21 ORZ01369.1 - 0.62 9.6 29.5 0.054 13.1 5.4 2.6 1 1 1 2 2 2 0 Intermediate filament protein MSP1a PF11670.8 ORZ01369.1 - 0.63 9.3 2.3 1.1 8.5 2.3 1.4 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) LMBR1 PF04791.16 ORZ01369.1 - 1.9 7.3 12.1 2.8 6.7 12.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HemX PF04375.14 ORZ01369.1 - 1.9 7.7 22.6 0.49 9.6 3.2 2.3 1 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_13 PF13166.6 ORZ01369.1 - 3.2 6.3 20.4 0.28 9.8 3.7 2.1 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.8 ORZ01369.1 - 3.6 5.0 26.6 5 4.5 26.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nas2_N PF18265.1 ORZ01369.1 - 5.5 7.0 16.4 2.8 7.9 1.1 3.9 3 1 1 4 4 4 0 Nas2 N_terminal domain DUF641 PF04859.12 ORZ01369.1 - 6.5 7.1 23.0 1.1 9.6 5.9 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) ADIP PF11559.8 ORZ01369.1 - 7.2 6.7 27.8 0.47 10.5 7.8 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rotamase PF00639.21 ORZ01369.1 - 7.5 7.6 8.7 1.2 10.1 1.0 2.8 2 1 0 2 2 2 0 PPIC-type PPIASE domain DPBB_1 PF03330.18 ORZ01372.1 - 1.3e-11 44.6 0.2 3.2e-11 43.4 0.2 1.7 1 1 0 1 1 1 1 Lytic transglycolase SPX PF03105.19 ORZ01372.1 - 0.067 13.1 11.3 0.065 13.1 11.3 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 ORZ01372.1 - 0.18 10.3 16.8 0.18 10.3 16.8 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 ORZ01372.1 - 0.19 10.3 8.7 0.2 10.3 8.7 1.1 1 0 0 1 1 1 0 Hamartin protein Barwin PF00967.17 ORZ01372.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 Barwin family SOG2 PF10428.9 ORZ01372.1 - 0.3 10.2 18.1 0.29 10.3 18.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 ORZ01372.1 - 0.63 8.8 15.2 0.65 8.8 15.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP65_ASE1 PF03999.12 ORZ01372.1 - 3.3 6.3 15.9 3.6 6.2 15.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Suf PF05843.14 ORZ01372.1 - 4.7 7.1 7.6 5.7 6.8 7.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 ORZ01372.1 - 8.4 5.0 11.1 8.5 5.0 11.1 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 ORZ01372.1 - 8.5 4.4 16.7 10 4.1 16.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAP1 PF08601.10 ORZ01372.1 - 8.6 6.0 26.2 9.8 5.8 26.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Mito_carr PF00153.27 ORZ01373.1 - 8.2e-18 64.1 0.3 2.6e-10 40.1 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein AAA PF00004.29 ORZ01374.1 - 1.6e-43 148.3 0.0 2.8e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ01374.1 - 3.2e-12 46.1 0.3 9.2e-12 44.6 0.1 1.9 2 0 0 2 2 2 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORZ01374.1 - 2.5e-11 43.4 0.6 4.3e-11 42.6 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 ORZ01374.1 - 8.9e-07 29.2 0.0 2.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORZ01374.1 - 1.5e-06 28.7 0.1 0.0012 19.3 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORZ01374.1 - 1.8e-06 28.0 0.1 5.4e-05 23.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORZ01374.1 - 5.1e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORZ01374.1 - 0.0002 21.6 0.1 0.0087 16.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 ORZ01374.1 - 0.00048 19.7 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 ORZ01374.1 - 0.00074 18.7 0.0 0.0022 17.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 ORZ01374.1 - 0.0015 17.9 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORZ01374.1 - 0.0018 18.8 0.0 0.0054 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORZ01374.1 - 0.002 17.4 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 ORZ01374.1 - 0.0025 17.6 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ORZ01374.1 - 0.004 17.1 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 ORZ01374.1 - 0.005 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORZ01374.1 - 0.0074 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ORZ01374.1 - 0.0083 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Prot_ATP_OB_N PF17758.1 ORZ01374.1 - 0.0093 15.6 0.3 0.029 14.0 0.1 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 ORZ01374.1 - 0.0098 16.1 0.0 0.027 14.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 ORZ01374.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ORZ01374.1 - 0.02 14.2 0.3 0.098 12.0 0.0 2.2 2 1 1 3 3 3 0 KaiC Sigma54_activat PF00158.26 ORZ01374.1 - 0.022 14.5 0.1 0.077 12.7 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 ORZ01374.1 - 0.067 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 ORZ01374.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 ORZ01374.1 - 0.074 13.0 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 ORZ01374.1 - 0.094 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORZ01374.1 - 0.11 12.2 0.2 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORZ01374.1 - 0.16 11.5 0.7 0.33 10.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORZ01374.1 - 0.18 11.1 0.8 1.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Raptor_N PF14538.6 ORZ01376.1 - 0.055 13.4 0.1 0.22 11.4 0.1 2.1 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain GEMIN8 PF15348.6 ORZ01379.1 - 0.29 11.4 5.7 3.9 7.7 1.0 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Hexapep PF00132.24 ORZ01380.1 - 3.1e-06 26.7 10.0 0.00022 20.8 1.7 2.9 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 ORZ01380.1 - 0.042 12.8 2.0 0.07 12.1 2.0 1.4 1 1 0 1 1 1 0 L-fucokinase ATG16 PF08614.11 ORZ01381.1 - 2.3e-44 152.0 30.7 3.2e-44 151.6 30.7 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 ORZ01381.1 - 2.5e-40 135.7 15.3 2.3e-06 28.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01381.1 - 3.1e-18 65.8 3.2 0.0018 18.5 0.0 5.9 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORZ01381.1 - 1.8e-05 23.6 5.6 0.59 8.7 0.1 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORZ01381.1 - 9.9e-05 21.4 0.7 0.63 8.9 0.0 4.5 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORZ01381.1 - 0.00011 20.9 0.5 0.00044 18.9 0.1 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain DUF5046 PF16465.5 ORZ01381.1 - 0.00061 19.3 0.5 0.0027 17.2 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5046) WD40_like PF17005.5 ORZ01381.1 - 0.00099 18.5 0.0 0.15 11.3 0.0 3.4 3 1 0 3 3 3 1 WD40-like domain FLgD_tudor PF13861.6 ORZ01381.1 - 0.028 14.7 0.0 0.1 12.9 0.0 2.0 1 1 0 1 1 1 0 FlgD Tudor-like domain PQQ_3 PF13570.6 ORZ01381.1 - 0.068 13.7 0.5 1.7 9.3 0.0 3.5 5 0 0 5 5 5 0 PQQ-like domain Nbas_N PF15492.6 ORZ01381.1 - 0.078 12.3 0.1 0.9 8.8 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 ORZ01381.1 - 0.12 12.3 0.1 28 4.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 ORZ01381.1 - 0.16 11.9 0.7 2 8.5 0.1 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat DUF2120 PF09893.9 ORZ01381.1 - 0.97 9.5 10.0 0.15 12.1 4.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) TSC22 PF01166.18 ORZ01381.1 - 7.2 7.0 21.1 0.7 10.2 3.0 4.2 3 1 1 4 4 4 0 TSC-22/dip/bun family Nrap_D5 PF17406.2 ORZ01382.1 - 5.2e-53 179.1 0.0 3e-52 176.7 0.0 2.1 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 ORZ01382.1 - 4e-46 157.1 0.1 4.9e-45 153.5 0.0 2.2 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 ORZ01382.1 - 1.5e-45 155.1 0.0 2.7e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 ORZ01382.1 - 2.8e-45 153.8 0.1 1.3e-41 141.9 0.0 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 ORZ01382.1 - 1.1e-42 145.7 0.1 2.1e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 ORZ01382.1 - 8.7e-30 103.7 0.1 2.8e-29 102.1 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 6 GrpE PF01025.19 ORZ01382.1 - 0.00047 19.9 1.7 0.00047 19.9 1.7 1.7 2 0 0 2 2 2 1 GrpE Pyr_redox_2 PF07992.14 ORZ01383.1 - 3e-20 72.7 0.0 2.8e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORZ01383.1 - 4.1e-05 23.0 0.1 0.0087 15.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 ORZ01383.1 - 0.00038 20.5 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORZ01383.1 - 0.0023 18.5 0.2 0.46 11.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORZ01383.1 - 0.0089 15.6 0.5 3.3 7.2 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORZ01383.1 - 0.0099 15.2 0.4 4.3 6.5 0.0 3.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORZ01383.1 - 0.022 15.0 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORZ01383.1 - 0.069 12.4 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ORZ01383.1 - 0.084 11.6 0.3 1.2 7.8 0.1 2.6 2 1 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 ORZ01383.1 - 0.19 10.8 0.0 0.45 9.5 0.0 1.6 1 1 1 2 2 2 0 Lycopene cyclase protein SNF2_N PF00176.23 ORZ01384.1 - 1e-67 228.4 0.9 5.8e-60 202.8 0.0 2.5 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORZ01384.1 - 2.4e-18 66.5 0.0 1.2e-17 64.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ01384.1 - 2e-05 24.7 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DZR PF12773.7 ORZ01384.1 - 0.04 14.0 1.2 0.091 12.8 1.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Cation_ATPase_C PF00689.21 ORZ01385.1 - 4.2e-46 156.9 11.2 4.2e-46 156.9 11.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORZ01385.1 - 2.5e-33 115.1 0.9 2.5e-33 115.1 0.9 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORZ01385.1 - 1.9e-19 69.5 0.0 4.7e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORZ01385.1 - 2.2e-18 67.3 2.1 1.4e-17 64.7 2.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ01385.1 - 1.9e-08 33.9 0.1 2.3e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ01385.1 - 3.1e-06 27.1 0.1 0.00028 20.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC_membrane PF00664.23 ORZ01386.1 - 3.5e-112 374.6 29.7 1.9e-56 191.7 16.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORZ01386.1 - 6.5e-72 240.5 2.6 1.1e-36 126.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 ORZ01386.1 - 6.2e-13 48.7 2.6 7.8e-06 25.5 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORZ01386.1 - 4.9e-09 35.5 0.1 0.0013 17.6 0.0 2.6 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 ORZ01386.1 - 6.4e-09 36.4 2.8 0.0027 18.1 0.3 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORZ01386.1 - 2.7e-08 34.2 0.9 0.0057 16.9 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORZ01386.1 - 2.8e-07 30.5 1.6 0.05 13.3 0.2 4.3 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORZ01386.1 - 2.3e-06 27.6 0.1 0.16 11.8 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 ORZ01386.1 - 3.3e-06 26.7 0.5 0.039 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 ORZ01386.1 - 1.9e-05 24.7 0.0 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 ORZ01386.1 - 8.5e-05 23.0 3.7 1 9.8 0.1 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 ORZ01386.1 - 0.00014 21.2 0.0 0.49 9.5 0.0 2.6 2 1 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 ORZ01386.1 - 0.00019 20.8 0.8 0.39 10.0 0.0 3.7 4 0 0 4 4 4 1 Zeta toxin SbcCD_C PF13558.6 ORZ01386.1 - 0.00021 21.5 4.1 0.36 11.1 0.4 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 ORZ01386.1 - 0.00033 20.2 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 ORZ01386.1 - 0.0011 19.1 0.0 1.2 9.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 ORZ01386.1 - 0.0033 17.2 1.4 0.15 11.8 0.0 3.0 3 1 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 ORZ01386.1 - 0.0046 17.0 0.1 8.9 6.3 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORZ01386.1 - 0.0049 17.4 0.4 3.6 8.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ORZ01386.1 - 0.0065 16.9 0.2 4.6 7.7 0.1 3.1 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 ORZ01386.1 - 0.0065 16.2 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORZ01386.1 - 0.01 16.1 0.1 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 ORZ01386.1 - 0.016 15.0 0.1 27 4.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 ORZ01386.1 - 0.018 14.7 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 ORZ01386.1 - 0.025 14.3 1.2 18 5.0 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 ORZ01386.1 - 0.04 13.6 0.0 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_25 PF13481.6 ORZ01386.1 - 0.059 12.9 0.2 17 4.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 ORZ01386.1 - 0.06 13.2 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 ORZ01386.1 - 0.095 12.5 0.2 7.6 6.2 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF4710 PF15828.5 ORZ01386.1 - 0.096 12.8 3.8 8.8 6.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) ATP-synt_ab PF00006.25 ORZ01386.1 - 0.2 11.3 0.6 10 5.7 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 ORZ01386.1 - 0.22 11.9 2.3 21 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 ORZ01386.1 - 0.24 11.5 1.3 28 4.8 0.0 3.4 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_23 PF13476.6 ORZ01386.1 - 0.6 10.6 15.4 11 6.4 0.0 3.8 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 ORZ01386.1 - 2 8.4 4.6 37 4.3 0.0 3.5 4 0 0 4 4 4 0 Helicase HerA, central domain MFS_1 PF07690.16 ORZ01387.1 - 9.7e-21 74.1 46.5 9.7e-21 74.1 46.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORZ01387.1 - 2.2e-07 29.7 24.9 4.4e-07 28.7 24.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ThiF PF00899.21 ORZ01388.1 - 6.8e-50 169.7 0.0 9.3e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 ORZ01388.1 - 4.5e-07 29.8 0.0 7.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 ORZ01388.1 - 0.0085 16.2 0.0 0.07 13.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ORZ01388.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ORZ01388.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-H2C2_2 PF13465.6 ORZ01389.1 - 3.5e-10 39.8 18.8 3e-06 27.4 3.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORZ01389.1 - 5.9e-10 39.1 17.0 1.6e-05 25.1 4.0 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ01389.1 - 4.1e-06 27.2 11.2 0.012 16.4 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORZ01389.1 - 0.028 14.7 1.3 0.85 10.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORZ01389.1 - 0.16 11.8 11.8 0.38 10.5 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 ORZ01389.1 - 0.22 12.2 3.2 1 10.0 3.0 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 ORZ01389.1 - 0.33 11.6 5.6 0.15 12.7 2.4 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain Zn-C2H2_12 PF18112.1 ORZ01389.1 - 3.1 8.4 8.8 47 4.6 0.1 3.1 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain NARP1 PF12569.8 ORZ01390.1 - 4.3e-181 603.3 22.5 4.3e-181 603.3 22.5 2.4 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 ORZ01390.1 - 3.4e-13 48.7 16.9 0.0032 17.6 0.4 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ01390.1 - 1.3e-12 46.8 47.5 2.5e-05 24.0 1.0 10.8 13 0 0 13 13 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ01390.1 - 5.5e-10 38.9 11.7 0.0026 18.0 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ01390.1 - 7.1e-10 39.3 31.3 0.0057 17.1 0.0 8.4 9 1 1 10 10 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ01390.1 - 9.4e-10 38.5 24.7 0.56 11.2 0.0 10.9 6 4 7 13 13 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ01390.1 - 1.2e-09 37.5 21.9 0.013 15.3 1.5 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ01390.1 - 4.1e-09 35.8 10.1 0.12 12.4 0.1 7.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ01390.1 - 9.6e-08 32.1 10.7 0.029 14.5 0.0 6.1 7 1 1 8 8 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ01390.1 - 7.8e-06 26.0 9.6 0.12 12.6 0.3 5.9 4 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORZ01390.1 - 1e-05 26.1 33.5 0.0035 17.9 0.0 8.3 10 1 0 10 10 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 ORZ01390.1 - 3.5e-05 24.0 2.0 0.48 11.2 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ01390.1 - 0.0039 16.8 10.6 0.075 12.7 0.1 5.8 6 0 0 6 6 5 1 TPR repeat HrpB1_HrpK PF09613.10 ORZ01390.1 - 0.012 15.3 0.3 0.36 10.5 0.0 3.2 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Wzy_C_2 PF11846.8 ORZ01390.1 - 0.019 14.9 1.4 0.32 10.9 0.1 3.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF1682 PF07946.14 ORZ01390.1 - 0.031 13.5 5.3 0.065 12.4 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PMSI1 PF15322.6 ORZ01390.1 - 0.19 11.1 2.2 0.31 10.5 2.2 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Coilin_N PF15862.5 ORZ01390.1 - 0.8 9.5 3.9 2 8.2 3.9 1.7 1 0 0 1 1 1 0 Coilin N-terminus Fis1_TPR_C PF14853.6 ORZ01390.1 - 3.4 7.8 11.0 14 5.8 0.0 4.8 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat FAD_binding_1 PF00667.20 ORZ01391.1 - 6.7e-44 150.1 0.0 1.1e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORZ01391.1 - 1.2e-23 84.0 0.0 2.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORZ01391.1 - 5.2e-18 65.7 0.0 2.7e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NodS PF05401.11 ORZ01391.1 - 0.18 11.4 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) ATP-synt_ab PF00006.25 ORZ01392.1 - 8e-64 215.2 0.7 1.4e-63 214.4 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORZ01392.1 - 2.2e-24 85.7 3.7 3.9e-24 84.9 2.8 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NACHT PF05729.12 ORZ01392.1 - 0.011 15.6 0.1 0.026 14.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 ORZ01392.1 - 0.012 14.8 1.0 0.016 14.4 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 ORZ01392.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORZ01392.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 ORZ01392.1 - 0.036 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 ORZ01392.1 - 0.037 14.4 0.9 0.11 12.9 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ORZ01392.1 - 0.049 14.1 0.0 0.45 10.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORZ01392.1 - 0.077 13.3 0.5 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain RnfC_N PF13375.6 ORZ01392.1 - 0.093 12.7 0.3 0.25 11.3 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain AAA_22 PF13401.6 ORZ01392.1 - 0.094 13.0 0.1 1 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORZ01392.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T3SS_ATPase_C PF18269.1 ORZ01392.1 - 0.27 11.1 2.2 0.92 9.4 0.3 2.6 2 1 0 2 2 2 0 T3SS EscN ATPase C-terminal domain TFIIA PF03153.13 ORZ01393.1 - 0.31 11.0 26.9 0.49 10.3 26.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC66 PF15236.6 ORZ01393.1 - 0.68 9.8 21.0 2 8.2 21.0 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 YdfA_immunity PF12127.8 ORZ01393.1 - 1.6 7.7 2.8 2.4 7.1 2.8 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial WDCP PF15390.6 ORZ01393.1 - 6.6 5.0 6.5 9.6 4.4 6.5 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family GHMP_kinases_N PF00288.26 ORZ01394.1 - 5.3e-11 42.6 0.1 1.3e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORZ01394.1 - 0.00013 22.2 0.0 0.00048 20.4 0.0 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal DUF4499 PF14934.6 ORZ01395.1 - 1.9e-14 53.7 1.2 3.7e-14 52.8 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 ORZ01395.1 - 2.1e-11 44.3 0.0 3.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) BTB_2 PF02214.22 ORZ01396.1 - 0.00068 19.9 0.0 0.032 14.6 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain HSBP1 PF06825.12 ORZ01397.1 - 1.4e-10 40.9 0.5 2e-10 40.3 0.5 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 ORZ01397.1 - 0.00024 20.9 0.1 0.0011 18.8 0.0 2.0 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin HMMR_N PF15905.5 ORZ01397.1 - 0.00072 19.1 3.2 0.00078 19.0 3.2 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Prefoldin_2 PF01920.20 ORZ01397.1 - 0.0021 18.0 0.9 0.014 15.3 0.3 1.9 1 1 1 2 2 2 1 Prefoldin subunit Baculo_PEP_C PF04513.12 ORZ01397.1 - 0.0027 17.8 7.5 0.0029 17.7 7.5 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 ORZ01397.1 - 0.0029 15.2 2.8 0.003 15.2 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CLZ PF16526.5 ORZ01397.1 - 0.0059 16.9 0.8 0.022 15.1 0.8 1.9 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cytochrom_B562 PF07361.11 ORZ01397.1 - 0.007 17.0 1.0 0.0075 16.9 1.0 1.1 1 0 0 1 1 1 1 Cytochrome b562 FKBP_N_2 PF18023.1 ORZ01397.1 - 0.011 15.8 1.0 0.014 15.5 1.0 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal IFT57 PF10498.9 ORZ01397.1 - 0.012 14.6 3.0 0.012 14.6 3.0 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HalX PF08663.10 ORZ01397.1 - 0.012 15.9 0.3 0.021 15.1 0.2 1.5 1 1 0 1 1 1 0 HalX domain Apolipoprotein PF01442.18 ORZ01397.1 - 0.015 15.2 0.8 0.017 15.0 0.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 ORZ01397.1 - 0.016 14.8 0.5 0.018 14.6 0.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region DASH_Spc19 PF08287.11 ORZ01397.1 - 0.016 15.1 1.7 0.018 14.9 1.7 1.1 1 0 0 1 1 1 0 Spc19 Thiamine_BP PF01910.17 ORZ01397.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Thiamine-binding protein Tmemb_cc2 PF10267.9 ORZ01397.1 - 0.019 14.1 2.6 0.02 14.1 2.6 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4618 PF15397.6 ORZ01397.1 - 0.021 14.3 1.8 0.025 14.0 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) WXG100 PF06013.12 ORZ01397.1 - 0.021 15.1 1.1 0.028 14.7 1.1 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Syntaxin_2 PF14523.6 ORZ01397.1 - 0.021 15.2 3.6 0.05 14.0 3.6 1.6 1 1 0 1 1 1 0 Syntaxin-like protein Ran-binding PF05508.11 ORZ01397.1 - 0.024 13.7 1.8 0.029 13.4 1.8 1.0 1 0 0 1 1 1 0 RanGTP-binding protein DUF2205 PF10224.9 ORZ01397.1 - 0.028 14.4 0.6 0.39 10.7 0.2 2.1 1 1 1 2 2 2 0 Short coiled-coil protein NPV_P10 PF05531.12 ORZ01397.1 - 0.03 14.8 3.4 0.045 14.2 1.3 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Corona_S2 PF01601.16 ORZ01397.1 - 0.033 12.7 1.4 0.037 12.5 1.4 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Fibritin_C PF07921.12 ORZ01397.1 - 0.034 14.3 0.6 0.047 13.8 0.5 1.4 1 1 0 1 1 1 0 Fibritin C-terminal region DUF4164 PF13747.6 ORZ01397.1 - 0.039 14.2 1.9 2.4 8.5 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 ORZ01397.1 - 0.045 13.8 0.9 0.094 12.8 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 ORZ01397.1 - 0.045 13.8 3.9 0.068 13.2 3.9 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF16 PF01519.16 ORZ01397.1 - 0.05 14.1 1.4 0.059 13.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 ORZ01397.1 - 0.071 13.5 2.8 1.5 9.2 0.2 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Rx_N PF18052.1 ORZ01397.1 - 0.075 13.3 0.2 0.088 13.1 0.2 1.3 1 0 0 1 1 1 0 Rx N-terminal domain Allexi_40kDa PF05549.11 ORZ01397.1 - 0.076 12.5 2.6 0.075 12.5 2.6 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Baculo_F PF12259.8 ORZ01397.1 - 0.089 11.3 4.4 0.095 11.2 4.4 1.0 1 0 0 1 1 1 0 Baculovirus F protein Muted PF14942.6 ORZ01397.1 - 0.097 13.0 2.5 0.11 12.9 2.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein IL11 PF07400.11 ORZ01397.1 - 0.11 12.2 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Interleukin 11 Tweety PF04906.13 ORZ01397.1 - 0.13 10.9 0.4 0.16 10.6 0.4 1.0 1 0 0 1 1 1 0 Tweety Fib_alpha PF08702.10 ORZ01397.1 - 0.15 12.3 3.2 0.25 11.5 3.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORZ01397.1 - 0.19 12.0 7.6 0.12 12.6 1.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA DASH_Dad1 PF08649.10 ORZ01397.1 - 0.83 9.9 3.3 1.4 9.2 0.4 2.2 1 1 2 3 3 3 0 DASH complex subunit Dad1 Lactamase_B PF00753.27 ORZ01398.1 - 2.3e-10 40.8 2.6 8.3e-10 39.0 2.6 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_19 PF14559.6 ORZ01398.1 - 3e-07 30.9 0.3 5.1e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ01398.1 - 3.8e-06 26.5 0.4 6.3e-06 25.8 0.4 1.4 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 ORZ01398.1 - 6.1e-06 25.8 1.2 1.1e-05 25.0 1.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ01398.1 - 3.5e-05 23.6 0.5 7.6e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ01398.1 - 0.0015 18.4 0.1 0.0032 17.4 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ01398.1 - 0.0027 17.8 0.4 0.0056 16.8 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 ORZ01398.1 - 0.0037 16.8 0.5 0.046 13.2 0.5 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TPR_14 PF13428.6 ORZ01398.1 - 0.0037 17.9 0.1 0.0083 16.9 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORZ01398.1 - 0.088 12.9 0.3 0.23 11.6 0.1 1.8 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 ORZ01398.1 - 0.19 12.1 0.1 0.39 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ01398.1 - 0.19 12.2 0.0 0.55 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ufd2P_core PF10408.9 ORZ01400.1 - 9e-221 734.8 12.8 1e-220 734.6 12.8 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 ORZ01400.1 - 2e-23 82.3 0.5 6.6e-23 80.7 0.5 1.9 1 0 0 1 1 1 1 U-box domain zf-C4H2 PF10146.9 ORZ01400.1 - 2.3 8.5 7.5 0.85 9.9 1.4 2.7 3 0 0 3 3 3 0 Zinc finger-containing protein DHFR_1 PF00186.19 ORZ01401.1 - 3.6e-36 124.3 0.0 9.1e-36 123.0 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase Telomere_res PF16684.5 ORZ01402.1 - 0.073 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Telomere resolvase Gp_dh_C PF02800.20 ORZ01403.1 - 2.9e-70 234.9 0.0 4.2e-70 234.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORZ01403.1 - 2.6e-39 133.6 0.1 6.4e-39 132.4 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORZ01403.1 - 0.02 15.0 0.0 0.065 13.3 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Myb_DNA-binding PF00249.31 ORZ01404.1 - 3.3e-05 24.0 0.0 8.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Alpha-2-MRAP_C PF06401.11 ORZ01404.1 - 0.013 15.4 0.5 0.85 9.5 0.3 2.4 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Rx_N PF18052.1 ORZ01404.1 - 0.03 14.6 1.2 0.054 13.8 1.2 1.4 1 0 0 1 1 1 0 Rx N-terminal domain TolA_bind_tri PF16331.5 ORZ01404.1 - 0.034 14.2 1.6 0.034 14.2 1.6 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF382 PF04037.13 ORZ01404.1 - 0.11 12.7 2.2 0.16 12.1 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF382) Bcr-Abl_Oligo PF09036.10 ORZ01404.1 - 0.11 12.5 1.2 0.22 11.6 1.2 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain TPD52 PF04201.15 ORZ01404.1 - 0.29 10.7 4.4 0.93 9.1 4.2 2.0 2 1 0 2 2 2 0 Tumour protein D52 family DUF3135 PF11333.8 ORZ01404.1 - 0.32 11.3 3.7 0.12 12.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) COG2 PF06148.11 ORZ01404.1 - 0.35 10.9 1.9 0.6 10.2 1.9 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 WD-3 PF09765.9 ORZ01405.1 - 6.6e-48 163.5 0.0 8.4e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 ORZ01405.1 - 1.9e-25 88.9 1.8 1.9e-25 88.9 1.8 1.7 2 0 0 2 2 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 ORZ01405.1 - 0.00012 22.4 2.7 0.00012 22.4 2.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORZ01405.1 - 0.012 15.9 1.3 0.034 14.4 1.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain ProRS-C_1 PF09180.11 ORZ01405.1 - 0.02 15.1 0.1 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal zf-3CxxC_2 PF17180.4 ORZ01405.1 - 0.029 15.1 3.1 4.1 8.2 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding domain zf-ANAPC11 PF12861.7 ORZ01405.1 - 0.035 14.2 0.7 0.1 12.6 0.7 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Casc1_N PF15927.5 ORZ01405.1 - 0.057 13.1 0.1 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus zf-HC5HC2H PF13771.6 ORZ01405.1 - 0.066 13.5 1.0 0.096 12.9 0.1 1.8 2 0 0 2 2 1 0 PHD-like zinc-binding domain Rubredoxin_2 PF18073.1 ORZ01405.1 - 0.36 10.6 2.0 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-RING-like PF08746.11 ORZ01405.1 - 0.89 9.9 5.5 0.26 11.6 1.4 2.3 2 1 0 2 2 2 0 RING-like domain PHD PF00628.29 ORZ01405.1 - 5.3 7.0 6.1 1.5 8.8 2.1 2.1 2 0 0 2 2 2 0 PHD-finger BUD22 PF09073.10 ORZ01407.1 - 0.045 13.1 38.1 0.0083 15.5 14.7 2.1 2 0 0 2 2 2 0 BUD22 Myc_N PF01056.18 ORZ01407.1 - 9.7 6.0 24.4 0.85 9.5 5.2 3.0 2 1 1 3 3 3 0 Myc amino-terminal region Ank_4 PF13637.6 ORZ01408.1 - 1.6e-14 54.0 0.6 1.6e-09 38.1 0.2 3.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORZ01408.1 - 2.5e-12 47.2 0.4 9.5e-07 29.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORZ01408.1 - 5.1e-08 32.6 0.1 0.0048 17.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORZ01408.1 - 1.6e-07 31.4 0.1 0.1 13.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 ORZ01408.1 - 4.1e-05 23.4 0.1 0.00055 19.8 0.1 2.6 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 ORZ01408.1 - 0.00043 20.5 0.3 0.071 13.5 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) EccE PF11203.8 ORZ01408.1 - 0.17 12.2 3.2 0.11 12.8 0.4 2.1 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Sugar_tr PF00083.24 ORZ01409.1 - 8.3e-90 301.8 28.7 5e-89 299.2 28.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ01409.1 - 3.6e-26 91.9 43.5 4e-19 68.8 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily COX7B PF05392.11 ORZ01409.1 - 0.19 11.4 0.5 8.2 6.2 0.0 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB IncE PF17627.2 ORZ01409.1 - 5.4 7.0 9.6 7.9 6.5 4.2 2.8 1 1 1 2 2 2 0 Inclusion membrane protein E NUDIX PF00293.28 ORZ01410.1 - 1.5e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain G-patch_2 PF12656.7 ORZ01411.1 - 6.2e-22 77.5 0.2 2.1e-21 75.8 0.2 2.0 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 ORZ01411.1 - 0.00035 20.4 0.1 0.00075 19.3 0.1 1.7 1 0 0 1 1 1 1 G-patch domain Gti1_Pac2 PF09729.9 ORZ01412.1 - 1.7e-58 197.7 0.2 1.7e-58 197.7 0.2 2.1 2 0 0 2 2 2 1 Gti1/Pac2 family Na_Ca_ex_C PF16494.5 ORZ01412.1 - 0.092 13.2 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain FAD_binding_1 PF00667.20 ORZ01413.1 - 5e-64 215.9 0.0 9e-64 215.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.19 ORZ01413.1 - 1.3e-26 93.8 3.7 2.5e-26 92.9 3.7 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_1 PF00175.21 ORZ01413.1 - 1.3e-13 51.5 0.0 5.3e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 ORZ01413.1 - 4e-05 23.8 0.0 0.00015 22.0 0.0 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Chrome_Resist PF09828.9 ORZ01413.1 - 0.052 14.0 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Chromate resistance exported protein Aldedh PF00171.22 ORZ01414.1 - 5.1e-135 450.6 0.1 5.8e-135 450.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORZ01414.1 - 0.12 11.4 0.9 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) DUF2229 PF09989.9 ORZ01414.1 - 0.13 11.9 0.5 0.24 11.0 0.5 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) MFS_1 PF07690.16 ORZ01415.1 - 3e-28 98.8 68.1 3.9e-19 68.8 38.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1689 PF07954.11 ORZ01415.1 - 2.1 8.8 4.1 14 6.1 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1689) Ribosomal_S17_N PF16205.5 ORZ01416.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 1 1 1 2 2 2 0 Ribosomal_S17 N-terminal MFS_1 PF07690.16 ORZ01417.1 - 1.6e-39 135.9 83.4 9.3e-28 97.1 47.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORZ01418.1 - 9.1e-25 87.3 45.9 7.4e-13 48.1 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORZ01418.1 - 2.7e-06 26.2 15.1 2.7e-06 26.2 15.1 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein DDDD PF10161.9 ORZ01418.1 - 0.73 9.6 0.1 0.73 9.6 0.1 2.2 3 0 0 3 3 3 0 Putative mitochondrial precursor protein PBP1_TM PF14812.6 ORZ01419.1 - 0.32 11.4 2.9 27 5.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SIN1 PF05422.12 ORZ01419.1 - 0.45 11.1 4.3 3.2 8.3 2.5 2.0 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) Hid1 PF12722.7 ORZ01419.1 - 4.3 5.3 7.0 5 5.1 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_tran PF00005.27 ORZ01420.1 - 4.9e-42 143.7 0.7 1.9e-22 80.3 0.0 3.7 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORZ01420.1 - 5e-16 59.4 0.5 0.0043 16.9 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORZ01420.1 - 2.1e-11 43.7 0.9 0.00082 18.9 0.0 4.5 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 ORZ01420.1 - 5.1e-06 26.4 9.3 5.1e-06 26.4 9.3 1.8 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 ORZ01420.1 - 5.6e-06 26.0 0.0 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ORZ01420.1 - 6.7e-06 26.6 0.2 0.19 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORZ01420.1 - 3.7e-05 24.3 0.1 0.14 12.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORZ01420.1 - 5.2e-05 23.2 0.2 0.091 12.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 ORZ01420.1 - 6.1e-05 23.0 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 ORZ01420.1 - 0.00027 21.2 1.7 0.92 9.8 0.0 3.6 3 2 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 ORZ01420.1 - 0.00052 20.4 0.0 1.6 9.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 ORZ01420.1 - 0.00054 20.4 0.0 1.6 9.2 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORZ01420.1 - 0.00096 19.2 0.2 0.89 9.6 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 ORZ01420.1 - 0.0018 18.3 0.7 0.46 10.6 0.0 3.5 4 0 0 4 4 4 1 50S ribosome-binding GTPase AAA_25 PF13481.6 ORZ01420.1 - 0.0033 17.0 0.0 4 7.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ORZ01420.1 - 0.0044 17.1 0.0 4 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 ORZ01420.1 - 0.0044 16.2 0.0 0.36 9.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.6 ORZ01420.1 - 0.0045 17.3 0.0 0.084 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORZ01420.1 - 0.005 17.0 0.3 0.77 9.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 ORZ01420.1 - 0.0058 16.4 0.0 2.9 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 ORZ01420.1 - 0.0061 16.2 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.9 ORZ01420.1 - 0.008 15.4 0.7 0.55 9.3 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.18 ORZ01420.1 - 0.0086 15.5 0.1 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.6 ORZ01420.1 - 0.011 15.5 0.4 0.37 10.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 ORZ01420.1 - 0.025 14.8 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORZ01420.1 - 0.028 13.9 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 ORZ01420.1 - 0.5 9.5 4.0 1.8 7.7 0.0 2.9 4 0 0 4 4 4 0 NB-ARC domain DUF87 PF01935.17 ORZ01420.1 - 0.59 10.2 2.6 4.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain Exo_endo_phos_2 PF14529.6 ORZ01421.1 - 8.8e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase GHL10 PF02638.15 ORZ01421.1 - 0.0063 15.6 0.0 0.0079 15.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 TelA PF05816.11 ORZ01422.1 - 0.071 12.2 0.4 0.1 11.6 0.4 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) GldH_lipo PF14109.6 ORZ01422.1 - 0.082 13.7 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 GldH lipoprotein MBOAT PF03062.19 ORZ01423.1 - 1.2e-18 67.7 9.6 1.3e-18 67.5 9.6 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORZ01423.1 - 0.6 10.4 6.8 0.17 12.2 2.9 2.1 2 1 0 2 2 2 0 Membrane bound O-acyl transferase family Pro_isomerase PF00160.21 ORZ01425.1 - 2e-49 167.9 0.0 5.4e-49 166.5 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ORZ01425.1 - 8.2e-08 32.8 0.0 0.0035 18.1 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01425.1 - 0.0015 18.8 0.0 0.43 10.9 0.1 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1180 PF06679.12 ORZ01426.1 - 0.0042 17.5 5.6 0.0072 16.8 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Pkinase PF00069.25 ORZ01427.1 - 8.8e-74 248.2 0.0 1.2e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01427.1 - 7.6e-34 117.2 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORZ01427.1 - 1.3e-11 45.0 3.5 1.3e-11 45.0 3.5 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORZ01427.1 - 1.2e-07 31.1 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORZ01427.1 - 0.00067 19.1 0.0 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 ORZ01427.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 C2 domain Imm7 PF15585.6 ORZ01427.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 7 Cnn_1N PF07989.11 ORZ01428.1 - 6.5e-10 39.0 6.8 1.2e-09 38.2 6.8 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 SusE PF14292.6 ORZ01428.1 - 0.031 14.5 0.5 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 SusE outer membrane protein Shugoshin_N PF07558.11 ORZ01428.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Macro PF01661.21 ORZ01429.1 - 5.7e-37 126.4 0.5 8.4e-37 125.8 0.5 1.3 1 0 0 1 1 1 1 Macro domain Asp PF00026.23 ORZ01430.1 - 4.5e-112 374.5 0.0 5.3e-112 374.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORZ01430.1 - 1.9e-13 51.1 1.0 7.8e-11 42.5 0.3 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORZ01430.1 - 0.00031 21.3 0.1 0.86 10.3 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 ORZ01430.1 - 0.0013 18.6 0.0 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ORZ01430.1 - 0.012 16.2 0.0 5.9 7.5 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease LAG1-DNAbind PF09271.11 ORZ01431.1 - 3.4e-45 154.4 0.1 3.4e-45 154.4 0.1 3.3 2 1 1 3 3 3 1 LAG1, DNA binding BTD PF09270.10 ORZ01431.1 - 1.9e-21 76.9 0.4 2.6e-11 44.0 0.0 3.3 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 ORZ01431.1 - 2.2e-06 27.6 0.1 8.1e-05 22.6 0.0 2.8 2 0 0 2 2 2 1 IPT/TIG domain SLC12 PF03522.15 ORZ01431.1 - 8.8 5.2 11.9 49 2.8 0.0 3.2 4 0 0 4 4 4 0 Solute carrier family 12 ALS_ss_C PF10369.9 ORZ01433.1 - 8.9e-18 64.3 0.8 5.2e-16 58.6 0.0 2.7 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 ORZ01433.1 - 1.1e-13 50.7 0.2 2.1e-13 49.7 0.2 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORZ01433.1 - 1.1e-08 34.7 0.1 2.2e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain LytR_C PF13399.6 ORZ01433.1 - 0.014 16.4 0.0 0.86 10.6 0.0 2.7 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Histone PF00125.24 ORZ01434.1 - 1.9e-23 83.3 0.5 2.3e-23 83.0 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORZ01434.1 - 1.8e-06 28.2 1.0 3.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORZ01434.1 - 0.00033 21.1 0.0 0.00064 20.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 ORZ01434.1 - 0.0052 17.0 0.0 0.0074 16.5 0.0 1.3 1 0 0 1 1 1 1 CENP-W protein RP-C PF03428.13 ORZ01434.1 - 0.04 13.6 0.2 0.13 11.9 0.2 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain CENP-T_C PF15511.6 ORZ01434.1 - 0.079 13.1 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Histone_H2A_C PF16211.5 ORZ01435.1 - 7.7e-21 73.5 1.4 1.4e-20 72.7 1.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORZ01435.1 - 1.2e-16 61.3 0.0 1.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORZ01435.1 - 7.6e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORZ01436.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORZ01436.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORZ01436.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORZ01436.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORZ01436.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORZ01436.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORZ01436.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 ORZ01437.1 - 2.6e-08 33.9 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORZ01437.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORZ01437.1 - 9.7e-05 22.7 0.1 0.00013 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORZ01437.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORZ01437.1 - 0.00035 20.8 0.1 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORZ01437.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORZ01437.1 - 0.059 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORZ01437.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Radical_SAM PF04055.21 ORZ01439.1 - 5.4e-24 85.4 0.0 1.2e-23 84.3 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 ORZ01439.1 - 2.4e-23 82.3 0.1 7.1e-23 80.7 0.0 1.9 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.25 ORZ01439.1 - 1.8e-21 76.9 0.0 4.4e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_NdrI PF07972.11 ORZ01439.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.9 1 1 0 1 1 1 0 NrdI Flavodoxin like Flavodoxin_3 PF12641.7 ORZ01439.1 - 0.15 11.7 0.8 6 6.5 0.1 2.3 2 0 0 2 2 2 0 Flavodoxin domain TMEM164 PF14808.6 ORZ01440.1 - 2.5e-27 95.9 4.3 3e-27 95.6 4.3 1.0 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.10 ORZ01440.1 - 5.9e-06 26.0 17.4 1.5e-05 24.6 17.4 1.6 1 1 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF2838 PF10998.8 ORZ01440.1 - 0.51 10.6 6.8 0.23 11.7 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) Med13_C PF06333.12 ORZ01441.1 - 5.4e-35 121.2 11.0 4.7e-27 95.1 1.3 4.1 4 1 1 5 5 5 2 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 ORZ01441.1 - 1.9e-19 70.4 12.5 2.3e-13 50.5 0.0 4.2 2 2 1 3 3 3 2 MID domain of medPIWI IMUP PF15761.5 ORZ01441.1 - 2.9 8.6 10.0 7.3 7.3 10.0 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 ORZ01441.1 - 9.8 5.7 11.7 3 7.4 8.6 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 ORZ01442.1 - 2.2e-27 95.5 12.8 2.6e-27 95.2 12.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Lactonase PF10282.9 ORZ01443.1 - 3.7e-61 207.3 0.1 4.2e-61 207.1 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Amidase_5 PF05382.13 ORZ01443.1 - 0.019 14.9 0.1 0.049 13.5 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase Lactonase PF10282.9 ORZ01444.1 - 8.2e-70 235.8 0.1 9.3e-70 235.6 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Sulfate_transp PF00916.20 ORZ01445.1 - 6e-107 357.7 23.1 7.5e-107 357.4 23.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORZ01445.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORZ01445.1 - 0.00021 21.6 5.0 0.00021 21.6 5.0 3.0 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORZ01445.1 - 0.0087 16.4 0.3 0.055 13.8 0.1 2.3 2 0 0 2 2 2 1 STAS domain Rad51 PF08423.11 ORZ01446.1 - 5.3e-40 137.3 0.1 5.8e-40 137.2 0.1 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 ORZ01446.1 - 0.019 14.6 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 ORZ01446.1 - 0.042 13.2 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 ORZ01446.1 - 0.28 11.2 2.0 0.23 11.5 0.5 1.7 2 1 1 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain HHH_5 PF14520.6 ORZ01447.1 - 1.3e-08 35.3 0.3 1.8e-08 34.9 0.3 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain BAF PF02961.14 ORZ01447.1 - 0.13 12.7 0.1 8 7.0 0.0 2.2 1 1 1 2 2 2 0 Barrier to autointegration factor Pkinase PF00069.25 ORZ01449.1 - 1.5e-27 96.6 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01449.1 - 9e-16 57.9 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ01449.1 - 4.2e-10 39.0 0.0 6.4e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORZ01449.1 - 0.0004 20.4 0.0 0.0092 15.9 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORZ01449.1 - 0.023 13.7 0.2 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-CCCH PF00642.24 ORZ01451.1 - 5.2e-19 67.7 13.0 8.9e-10 38.2 1.5 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORZ01451.1 - 8.7e-13 47.9 13.5 1.4e-06 28.1 5.4 2.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORZ01451.1 - 1.2e-10 41.0 14.4 3.5e-06 26.7 5.8 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORZ01451.1 - 6.9e-06 26.3 7.7 0.0023 18.3 0.7 2.5 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORZ01451.1 - 0.00013 22.6 7.9 0.056 14.1 0.7 2.0 1 1 1 2 2 2 2 Torus domain zf-CCHH PF10283.9 ORZ01451.1 - 0.13 12.3 8.6 1.9 8.6 2.3 2.5 2 0 0 2 2 2 0 PBZ domain ShK PF01549.24 ORZ01451.1 - 0.42 11.2 4.5 0.73 10.4 0.8 2.3 2 0 0 2 2 2 0 ShK domain-like ParA PF10609.9 ORZ01452.1 - 7.9e-100 333.3 0.0 9.3e-100 333.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORZ01452.1 - 7.2e-10 39.0 0.0 3.2e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORZ01452.1 - 1.5e-05 24.9 0.1 0.00014 21.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 ORZ01452.1 - 3.9e-05 23.0 0.4 0.00016 21.0 0.1 2.0 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 ORZ01452.1 - 0.00016 21.3 0.0 0.087 12.3 0.1 2.6 3 0 0 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 ORZ01452.1 - 0.00063 19.4 0.0 0.00091 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 ORZ01452.1 - 0.0008 18.8 0.1 0.0039 16.5 0.1 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 ORZ01452.1 - 0.0014 18.5 0.0 0.057 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 ORZ01452.1 - 0.0035 16.9 0.1 0.021 14.3 0.1 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 ORZ01452.1 - 0.0037 16.3 0.1 0.0052 15.8 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 ORZ01452.1 - 0.0093 15.9 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase TF_Zn_Ribbon PF08271.12 ORZ01452.1 - 0.013 15.0 0.1 0.033 13.7 0.1 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding CLP1_P PF16575.5 ORZ01452.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop YjeF_N PF03853.15 ORZ01452.1 - 0.092 12.6 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus AAA_16 PF13191.6 ORZ01452.1 - 0.097 13.0 0.2 0.19 12.1 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ORZ01452.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 NACHT domain SelB-wing_3 PF09107.11 ORZ01452.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix PcrB PF01884.17 ORZ01452.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 PcrB family SNARE PF05739.19 ORZ01453.1 - 4.4e-07 29.8 3.4 1.2e-06 28.4 1.1 2.1 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 ORZ01453.1 - 0.0092 15.7 0.3 0.011 15.5 0.3 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Fusion_gly PF00523.18 ORZ01453.1 - 0.017 13.4 0.1 0.017 13.4 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 TBCA PF02970.16 ORZ01453.1 - 0.061 13.6 0.6 0.085 13.2 0.6 1.4 1 1 0 1 1 1 0 Tubulin binding cofactor A SlyX PF04102.12 ORZ01453.1 - 0.062 13.9 3.3 3.9 8.2 0.2 2.1 2 0 0 2 2 2 0 SlyX adh_short PF00106.25 ORZ01455.1 - 5.1e-35 120.7 0.1 7e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ01455.1 - 1.9e-31 109.4 0.0 2.3e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORZ01455.1 - 3.2e-05 23.9 1.3 0.0001 22.3 1.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORZ01455.1 - 0.0056 16.2 0.2 0.025 14.0 0.2 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ORZ01455.1 - 0.057 13.7 0.2 0.24 11.7 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain RIFIN PF02009.16 ORZ01455.1 - 0.2 11.5 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Rifin Zip PF02535.22 ORZ01456.1 - 2.6e-34 118.9 21.0 8.4e-32 110.7 21.0 2.6 1 1 0 1 1 1 1 ZIP Zinc transporter WD40 PF00400.32 ORZ01457.1 - 2.8e-50 167.2 17.8 1.9e-09 37.9 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 ORZ01457.1 - 1.9e-44 151.1 2.6 4.6e-44 149.8 1.9 2.0 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 ORZ01457.1 - 8.5e-11 42.0 0.0 0.025 14.9 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ01457.1 - 3e-06 26.8 0.0 0.07 12.4 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 ORZ01457.1 - 4.8e-06 25.5 0.1 0.89 8.1 0.0 3.9 4 0 0 4 4 4 3 Nucleoporin Nup120/160 LisH PF08513.11 ORZ01457.1 - 1.4e-05 24.8 1.1 9.5e-05 22.2 0.0 2.6 2 0 0 2 2 2 1 LisH Ge1_WD40 PF16529.5 ORZ01457.1 - 0.044 12.7 0.1 0.58 9.1 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LPD18 PF18832.1 ORZ01458.1 - 0.0023 17.9 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 18 Acetyltransf_1 PF00583.25 ORZ01459.1 - 1.8e-12 47.6 0.0 2.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORZ01459.1 - 1.3e-08 34.8 0.0 1.7e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORZ01459.1 - 1.3e-05 25.5 0.1 1.9e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Phosphonate-bd PF12974.7 ORZ01460.1 - 3.7e-06 26.7 0.0 4.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 ORZ01460.1 - 0.0013 18.7 0.0 0.084 12.8 0.0 2.1 2 0 0 2 2 2 2 NMT1/THI5 like HTH_23 PF13384.6 ORZ01460.1 - 0.15 11.9 0.0 0.78 9.6 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain GST_C_3 PF14497.6 ORZ01461.1 - 1.6e-13 50.7 0.0 3.3e-13 49.7 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORZ01461.1 - 0.0033 17.6 0.0 0.0057 16.9 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MOZ_SAS PF01853.18 ORZ01462.1 - 6.2e-74 247.5 0.4 1.3e-73 246.5 0.4 1.5 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 ORZ01462.1 - 8.1e-22 76.6 1.6 8.1e-22 76.6 1.6 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 ORZ01462.1 - 0.0011 19.3 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AOX PF01786.17 ORZ01464.1 - 1.5e-71 240.4 1.0 1.8e-71 240.2 1.0 1.0 1 0 0 1 1 1 1 Alternative oxidase NADH-u_ox-rdase PF10785.9 ORZ01464.1 - 0.13 12.9 0.1 0.31 11.8 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit B12D PF06522.11 ORZ01465.1 - 3.9e-21 74.6 0.1 4.8e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ribosomal_L28e PF01778.17 ORZ01466.1 - 3.2e-30 105.2 5.2 5.1e-30 104.6 5.2 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Pan3_PK PF18101.1 ORZ01467.1 - 7.7e-67 223.5 0.2 1.4e-66 222.7 0.2 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 ORZ01467.1 - 1.5e-05 24.6 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01467.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PIP5K PF01504.18 ORZ01468.1 - 1.7e-97 325.9 0.0 2.4e-97 325.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.32 ORZ01469.1 - 1.6e-37 126.9 22.6 7.4e-07 29.8 0.5 11.4 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01469.1 - 2.6e-20 72.5 1.6 0.0092 16.3 0.1 7.9 3 3 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ01469.1 - 1.3e-07 31.7 0.8 0.056 13.3 0.0 4.1 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORZ01469.1 - 5.3e-06 26.0 0.1 0.0032 16.8 0.0 3.3 1 1 0 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 ORZ01469.1 - 2.6e-05 24.5 5.5 0.035 14.6 0.1 4.8 5 0 0 5 5 5 2 PQQ-like domain RAB3GAP2_N PF14655.6 ORZ01469.1 - 0.017 14.4 0.0 0.77 8.9 0.0 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.21 ORZ01469.1 - 0.043 13.8 1.8 71 3.6 0.0 4.8 4 0 0 4 4 4 0 PQQ enzyme repeat PALP PF00291.25 ORZ01470.1 - 1.3e-70 238.1 2.0 1.6e-70 237.8 2.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3335 PF11814.8 ORZ01470.1 - 0.012 15.1 0.2 0.029 13.8 0.2 1.6 1 0 0 1 1 1 0 Peptidase_C39 like family DFP PF04127.15 ORZ01470.1 - 0.032 14.1 0.5 0.056 13.3 0.5 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Stork_head PF10264.9 ORZ01470.1 - 0.16 12.1 0.0 0.54 10.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain SMC_N PF02463.19 ORZ01471.1 - 6e-35 120.7 10.3 1e-34 119.9 10.3 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORZ01471.1 - 2e-12 48.0 38.8 3.2e-06 27.8 38.8 3.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ORZ01471.1 - 1.8e-08 34.5 11.5 3.2e-07 30.4 11.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORZ01471.1 - 8.3e-06 25.8 0.1 8.3e-06 25.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORZ01471.1 - 5.1e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain HTH_26 PF13443.6 ORZ01471.1 - 0.13 12.7 1.0 27 5.3 0.0 4.4 4 0 0 4 4 4 0 Cro/C1-type HTH DNA-binding domain NPV_P10 PF05531.12 ORZ01471.1 - 2.2 8.8 9.5 9.2 6.8 0.1 4.3 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein UDG PF03167.19 ORZ01472.1 - 2.5e-27 95.8 0.3 6.6e-27 94.4 0.1 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF3235 PF11574.8 ORZ01472.1 - 0.089 13.7 0.3 0.26 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) zf-RING_2 PF13639.6 ORZ01473.1 - 2.7e-10 40.4 11.3 2.7e-10 40.4 11.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORZ01473.1 - 3.2e-06 27.3 12.7 1e-05 25.7 12.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORZ01473.1 - 4.4e-06 26.4 10.4 4.4e-06 26.4 10.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORZ01473.1 - 9.9e-06 25.2 7.0 9.9e-06 25.2 7.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORZ01473.1 - 7.3e-05 22.8 4.8 0.00017 21.6 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 ORZ01473.1 - 0.00086 19.1 9.6 0.00086 19.1 9.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ01473.1 - 0.0082 16.1 7.7 0.0082 16.1 7.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORZ01473.1 - 0.014 15.4 9.9 0.022 14.8 7.8 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORZ01473.1 - 0.024 14.5 7.3 0.024 14.5 7.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 ORZ01473.1 - 0.083 13.0 5.0 0.17 12.0 5.0 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_10 PF16685.5 ORZ01473.1 - 0.18 12.0 5.9 0.36 11.0 5.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 PHD PF00628.29 ORZ01473.1 - 1 9.3 10.3 3.3 7.7 10.2 1.9 1 1 1 2 2 2 0 PHD-finger FANCL_C PF11793.8 ORZ01473.1 - 1 9.6 10.9 5.2 7.3 10.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 ORZ01473.1 - 2.4 8.0 6.7 5.8 6.8 6.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 ORZ01473.1 - 2.4 7.8 10.3 5.9 6.6 10.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Proteasome PF00227.26 ORZ01474.1 - 3.7e-62 209.2 0.1 5.1e-62 208.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORZ01474.1 - 5.2e-13 48.4 0.1 1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ELFV_dehydrog_N PF02812.18 ORZ01475.1 - 6.9e-59 197.4 0.0 1.2e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORZ01475.1 - 5.6e-58 196.5 0.1 3.3e-55 187.5 0.0 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase tRNA_edit PF04073.15 ORZ01476.1 - 1.1e-07 32.0 0.0 3.3e-07 30.4 0.0 1.8 1 1 1 2 2 2 1 Aminoacyl-tRNA editing domain DUF89 PF01937.19 ORZ01477.1 - 2e-114 382.3 2.6 2.2e-114 382.1 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Chitin_synth_2 PF03142.15 ORZ01478.1 - 7.3e-275 912.5 0.0 9.7e-275 912.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORZ01478.1 - 4.9e-15 56.1 0.0 5.3e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORZ01478.1 - 4.1e-12 46.4 3.9 1.9e-11 44.3 3.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORZ01478.1 - 6.4e-05 22.5 0.0 0.005 16.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORZ01478.1 - 0.055 13.3 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Epimerase PF01370.21 ORZ01479.1 - 3.7e-25 88.8 0.0 4.7e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORZ01479.1 - 3e-12 46.6 0.0 5.9e-12 45.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORZ01479.1 - 2.9e-11 42.9 0.0 4.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORZ01479.1 - 4.7e-09 36.4 0.0 8.8e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORZ01479.1 - 5.4e-09 35.6 0.0 7.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 ORZ01479.1 - 5.1e-05 23.5 0.1 0.0017 18.6 0.0 2.9 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 ORZ01479.1 - 0.00059 19.1 0.7 0.0074 15.5 0.7 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORZ01479.1 - 0.0022 17.2 0.1 0.0041 16.3 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORZ01479.1 - 0.0076 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF4434 PF14488.6 ORZ01479.1 - 0.11 12.5 0.8 0.19 11.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) RhoGEF PF00621.20 ORZ01480.1 - 8.2e-33 114.2 2.1 9.4e-33 114.0 2.1 1.0 1 0 0 1 1 1 1 RhoGEF domain GHMP_kinases_N PF00288.26 ORZ01481.1 - 2.4e-13 50.1 0.9 6.3e-13 48.8 0.4 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORZ01481.1 - 1.7e-05 25.1 0.0 4.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4829 PF16111.5 ORZ01482.1 - 0.0021 18.9 2.0 0.0036 18.1 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4829) Herpes_UL6 PF01763.16 ORZ01482.1 - 0.44 9.0 5.2 0.32 9.5 3.3 1.6 2 0 0 2 2 2 0 Herpesvirus UL6 like Spc7 PF08317.11 ORZ01482.1 - 0.82 8.5 12.5 1.8 7.4 12.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Alpha-2-MRAP_C PF06401.11 ORZ01482.1 - 0.85 9.5 14.4 0.05 13.6 9.0 1.6 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF812 PF05667.11 ORZ01482.1 - 2.1 7.1 15.1 0.47 9.3 10.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Atg14 PF10186.9 ORZ01482.1 - 7 5.6 11.1 13 4.8 11.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 ORZ01482.1 - 7.8 6.0 12.3 1.9 8.0 5.1 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MR_MLE_C PF13378.6 ORZ01483.1 - 1.5e-55 188.1 0.0 2.4e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ORZ01483.1 - 5.5e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Exo_endo_phos PF03372.23 ORZ01485.1 - 7.4e-08 32.2 0.1 1.8e-07 30.9 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FXMRP1_C_core PF12235.8 ORZ01485.1 - 0.15 12.7 2.4 0.3 11.7 2.4 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal BolA PF01722.18 ORZ01486.1 - 7.2e-32 109.5 0.7 8.5e-32 109.3 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein Retrotrans_gag PF03732.17 ORZ01487.1 - 0.1 12.9 0.4 0.86 9.9 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein BRE1 PF08647.11 ORZ01488.1 - 0.0087 16.1 5.6 0.0087 16.1 5.6 3.1 2 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase DUF4472 PF14739.6 ORZ01488.1 - 0.016 16.0 3.4 0.016 16.0 3.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) CENP-F_leu_zip PF10473.9 ORZ01488.1 - 0.018 15.1 5.3 0.018 15.1 5.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 ORZ01488.1 - 0.17 12.0 22.8 1.1 9.3 11.3 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 ORZ01488.1 - 0.5 9.7 22.9 1.5 8.2 5.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 ORZ01488.1 - 1.8 8.6 19.0 4.8 7.3 6.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 ORZ01488.1 - 2.8 7.7 14.3 0.61 9.9 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Translin PF01997.16 ORZ01489.1 - 2.2e-34 119.3 0.0 9.2e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 Translin family GMP_synt_C PF00958.22 ORZ01489.1 - 0.066 13.3 0.2 0.65 10.1 0.1 2.3 2 1 0 2 2 2 0 GMP synthase C terminal domain CS PF04969.16 ORZ01490.1 - 9.2e-11 42.6 0.1 1.5e-10 42.0 0.1 1.3 1 0 0 1 1 1 1 CS domain GATA PF00320.27 ORZ01491.1 - 5.5e-16 57.9 3.3 5.5e-16 57.9 3.3 2.6 2 0 0 2 2 2 1 GATA zinc finger FYDLN_acid PF09538.10 ORZ01491.1 - 0.02 15.6 5.3 0.036 14.8 3.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TF_Zn_Ribbon PF08271.12 ORZ01491.1 - 0.073 12.6 3.3 0.087 12.4 0.3 2.5 3 0 0 3 3 3 0 TFIIB zinc-binding Presenilin PF01080.17 ORZ01491.1 - 0.34 9.6 4.2 0.45 9.2 4.2 1.3 1 0 0 1 1 1 0 Presenilin Vps36-NZF-N PF16988.5 ORZ01491.1 - 0.58 9.6 6.1 1 8.8 0.6 3.5 3 1 1 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn-ribbon_8 PF09723.10 ORZ01491.1 - 1 9.5 8.2 3.6 7.8 0.2 3.3 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 ORZ01491.1 - 1.6 8.8 10.2 6.8 6.8 7.3 3.1 2 1 2 4 4 4 0 Double zinc ribbon ATP-synt_E PF05680.12 ORZ01491.1 - 1.9 8.9 5.9 2.8 8.3 1.7 2.5 2 0 0 2 2 2 0 ATP synthase E chain zf-C4pol PF14260.6 ORZ01491.1 - 4.4 7.9 9.6 22 5.6 3.2 3.6 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta CHGN PF05679.16 ORZ01492.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.4 1 1 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase C_GCAxxG_C_C PF09719.10 ORZ01492.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) SPX PF03105.19 ORZ01492.1 - 6.3 6.6 10.5 9.9 6.0 10.5 1.4 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 ORZ01492.1 - 7.7 6.4 10.6 14 5.6 10.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 ORZ01493.1 - 0.00017 21.8 7.8 0.00018 21.7 7.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 ORZ01493.1 - 0.061 13.3 8.3 0.093 12.7 8.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 ORZ01493.1 - 0.14 11.8 18.0 0.2 11.3 18.0 1.2 1 0 0 1 1 1 0 Spt20 family PBP_sp32 PF07222.12 ORZ01493.1 - 0.53 9.7 8.1 0.91 8.9 8.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TMPIT PF07851.13 ORZ01493.1 - 1.7 7.8 5.7 2.7 7.1 5.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 ORZ01493.1 - 2.3 7.5 17.3 4.3 6.6 17.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CHD5 PF04420.14 ORZ01493.1 - 5.8 6.8 6.8 12 5.7 6.8 1.5 1 0 0 1 1 1 0 CHD5-like protein DUF4834 PF16118.5 ORZ01493.1 - 7.9 7.5 9.3 18 6.4 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Peptidase_S64 PF08192.11 ORZ01493.1 - 9.3 4.6 9.7 14 4.0 9.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4112 PF13430.6 ORZ01494.1 - 3.3e-25 88.4 0.1 4.2e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PTCB-BRCT PF12738.7 ORZ01495.1 - 3.8e-14 52.4 0.7 1e-10 41.4 0.1 3.0 3 0 0 3 3 3 2 twin BRCT domain BRCT_2 PF16589.5 ORZ01495.1 - 3.4e-12 46.6 0.0 0.0033 17.8 0.0 3.4 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORZ01495.1 - 9e-12 45.2 0.1 7.8e-05 23.0 0.0 3.1 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 ORZ01495.1 - 0.0068 16.3 0.0 14 5.6 0.0 3.3 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 ORZ01495.1 - 0.2 11.9 0.2 26 5.2 0.0 3.0 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain PRIMA1 PF16101.5 ORZ01495.1 - 3.4 7.7 12.1 2 8.5 6.2 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TCTP PF00838.17 ORZ01496.1 - 3.4e-76 255.2 0.8 3.8e-76 255.1 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Glyco_transf_7N PF13733.6 ORZ01496.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 EMP70 PF02990.16 ORZ01497.1 - 6.1e-210 698.3 0.4 7.8e-210 697.9 0.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4131 PF13567.6 ORZ01497.1 - 6.3 6.4 26.5 1.4 8.6 0.1 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF4131) Peptidase_S41 PF03572.18 ORZ01498.1 - 2.1e-07 30.6 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 DUF3048_C PF17479.2 ORZ01498.1 - 0.064 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain AA_kinase PF00696.28 ORZ01499.1 - 4e-38 131.4 0.1 6.2e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 ORZ01499.1 - 1.3e-11 44.1 0.7 3.9e-05 23.3 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 ORZ01499.1 - 3.8e-10 39.4 5.8 1.2e-07 31.4 1.6 2.6 2 0 0 2 2 2 2 ACT domain MFS_1 PF07690.16 ORZ01501.1 - 3e-32 111.9 39.3 7.6e-19 67.8 20.7 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 ORZ01501.1 - 2.9e-15 55.7 24.3 5.5e-15 54.8 24.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) B12-binding_2 PF02607.17 ORZ01501.1 - 0.0099 16.3 0.1 0.051 14.0 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain DUF1751 PF08551.10 ORZ01501.1 - 0.083 13.5 4.0 0.23 12.0 1.1 2.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Beta-APP PF03494.13 ORZ01501.1 - 0.37 10.7 2.7 0.93 9.4 0.1 2.9 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Pyr_redox_2 PF07992.14 ORZ01502.1 - 5.2e-26 91.5 0.0 6.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORZ01502.1 - 3.7e-07 30.6 0.0 7.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 ORZ01502.1 - 0.00092 18.6 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_3 PF13738.6 ORZ01502.1 - 0.0021 17.4 0.0 0.014 14.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORZ01502.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Cation_efflux PF01545.21 ORZ01503.1 - 7.5e-55 185.8 8.5 9.1e-55 185.5 8.5 1.1 1 0 0 1 1 1 1 Cation efflux family WD40 PF00400.32 ORZ01504.1 - 7.1e-14 52.0 18.7 0.0029 18.4 0.1 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 ORZ01504.1 - 9.5e-08 31.1 7.7 0.011 14.4 0.3 4.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORZ01504.1 - 2.3e-05 24.6 2.7 1.2 9.5 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORZ01504.1 - 0.00012 21.0 2.0 0.029 13.1 0.0 3.3 2 1 2 4 4 4 2 Nup133 N terminal like PALB2_WD40 PF16756.5 ORZ01504.1 - 0.018 14.0 1.2 5.4 5.8 0.0 2.9 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain FCP1_C PF09309.10 ORZ01504.1 - 0.56 10.0 4.6 1.6 8.5 2.2 2.7 2 0 0 2 2 2 0 FCP1, C-terminal Metallothio_2 PF01439.18 ORZ01504.1 - 0.9 10.5 25.5 0.25 12.3 11.8 3.1 1 1 1 2 2 2 0 Metallothionein Acetyltransf_1 PF00583.25 ORZ01506.1 - 3.3e-06 27.3 0.0 4.9e-05 23.5 0.0 2.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORZ01506.1 - 0.02 14.8 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORZ01506.1 - 0.035 14.5 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CDC50 PF03381.15 ORZ01507.1 - 5.9e-85 285.2 1.0 7.4e-85 284.9 1.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MIOX PF05153.15 ORZ01508.1 - 5.5e-113 376.6 5.6 8.6e-113 376.0 5.6 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 ORZ01508.1 - 0.055 13.7 0.2 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 HD domain Sdh5 PF03937.16 ORZ01508.1 - 0.076 13.0 0.4 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase RIBIOP_C PF04950.12 ORZ01509.1 - 9e-120 399.5 0.4 2.1e-119 398.3 0.4 1.7 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORZ01509.1 - 8.2e-23 80.3 0.0 1.9e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain URO-D PF01208.17 ORZ01510.1 - 3.5e-137 457.2 0.0 3.9e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Arrestin_C PF02752.22 ORZ01511.1 - 5.1e-21 75.5 0.1 3.9e-18 66.2 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORZ01511.1 - 2.3e-15 56.9 0.0 2.9e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORZ01511.1 - 0.015 15.0 0.0 0.061 13.0 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like Defensin_propep PF00879.18 ORZ01512.1 - 0.47 10.8 2.6 1 9.7 2.6 1.5 1 0 0 1 1 1 0 Defensin propeptide DUF4328 PF14219.6 ORZ01513.1 - 0.036 13.6 0.2 0.082 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) CD34_antigen PF06365.12 ORZ01513.1 - 0.06 12.9 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family TMEM131_like PF12371.8 ORZ01513.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 131-like WD40 PF00400.32 ORZ01514.1 - 2.9e-23 81.7 1.3 0.00023 21.9 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01514.1 - 4.2e-15 55.8 0.0 4.5e-07 30.1 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ01514.1 - 2.1e-07 30.6 0.0 5e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 WD40-like domain eIF2A PF08662.11 ORZ01514.1 - 2.6e-05 24.2 0.1 0.0048 16.8 0.0 2.8 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 ORZ01514.1 - 0.06 13.9 2.8 7.6 7.2 0.1 3.9 4 1 0 4 4 4 0 PQQ-like domain MucBP_2 PF17965.1 ORZ01514.1 - 0.087 13.4 0.7 0.5 11.0 0.1 2.5 3 0 0 3 3 3 0 Mucin binding domain SdiA-regulated PF06977.11 ORZ01514.1 - 0.22 10.7 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 SdiA-regulated Frtz PF11768.8 ORZ01514.1 - 0.26 9.6 0.0 2.1 6.6 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Sulfate_transp PF00916.20 ORZ01515.1 - 2.1e-106 355.9 18.3 2.6e-106 355.6 18.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORZ01515.1 - 6.5e-11 41.9 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORZ01515.1 - 0.00081 19.8 2.3 0.00081 19.8 2.3 2.9 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORZ01515.1 - 0.0074 16.6 0.2 0.016 15.5 0.2 1.6 1 0 0 1 1 1 1 STAS domain bZIP_1 PF00170.21 ORZ01516.1 - 1.8e-09 37.6 14.5 5.1e-09 36.1 13.9 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORZ01516.1 - 5.3e-06 26.4 13.0 5.3e-06 26.4 13.0 2.5 1 1 1 2 2 2 1 Basic region leucine zipper GIT_CC PF16559.5 ORZ01516.1 - 0.016 15.0 3.0 0.037 13.9 3.0 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_Maf PF03131.17 ORZ01516.1 - 0.03 14.9 12.4 0.03 14.9 12.4 2.6 3 0 0 3 3 3 0 bZIP Maf transcription factor Ribosomal_S20p PF01649.18 ORZ01516.1 - 0.98 10.1 5.9 1.9 9.2 5.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 RNase_PH PF01138.21 ORZ01517.1 - 1.7e-25 90.0 0.0 4.7e-25 88.6 0.0 1.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORZ01517.1 - 8.6e-06 25.7 0.0 2.3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 BNR_4 PF15892.5 ORZ01517.1 - 0.00038 19.9 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member zf-C2H2 PF00096.26 ORZ01518.1 - 0.067 13.7 3.9 0.067 13.7 3.9 2.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ01518.1 - 1.7 9.7 9.9 0.16 12.9 2.8 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger LRR_8 PF13855.6 ORZ01519.1 - 1.5e-40 136.7 48.8 1.8e-11 43.6 1.7 8.5 6 3 2 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 ORZ01519.1 - 8.6e-33 111.8 53.4 1.3e-07 31.8 2.6 10.1 2 2 15 17 17 17 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORZ01519.1 - 7.4e-13 48.4 22.8 0.00022 20.8 1.4 5.4 3 2 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 ORZ01519.1 - 6.4e-07 29.1 45.2 2 9.3 0.1 14.2 13 3 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 ORZ01519.1 - 3.4e-06 26.7 42.0 0.72 10.1 0.0 11.5 12 0 0 12 12 12 4 Leucine Rich repeat LRR_2 PF07723.13 ORZ01519.1 - 0.0014 19.2 1.2 8.7 7.2 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_5 PF13306.6 ORZ01519.1 - 0.0037 17.2 0.3 0.47 10.4 0.0 2.8 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) CHAP PF05257.16 ORZ01520.1 - 4e-14 53.0 4.2 9.8e-14 51.7 4.2 1.7 1 0 0 1 1 1 1 CHAP domain SH3_3 PF08239.11 ORZ01520.1 - 0.0022 18.2 0.1 0.0079 16.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain p450 PF00067.22 ORZ01521.1 - 1.5e-77 261.3 0.3 1.8e-77 261.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1712 PF08217.11 ORZ01522.1 - 1.2e-31 109.9 0.2 1.8e-30 106.0 0.0 2.0 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Chalcone_2 PF16035.5 ORZ01522.1 - 0.13 12.0 0.2 0.74 9.6 0.1 2.1 2 0 0 2 2 2 0 Chalcone isomerase like NUDIX PF00293.28 ORZ01523.1 - 2e-12 47.3 0.1 3.5e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain PAP2_3 PF14378.6 ORZ01524.1 - 9.6e-23 80.9 10.0 9.6e-23 80.9 10.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 ORZ01524.1 - 2.2e-07 30.7 10.1 2.2e-07 30.7 10.1 2.0 2 1 0 2 2 2 1 PAP2 superfamily CaMBD PF02888.16 ORZ01526.1 - 1.7 8.9 10.8 3.5 7.9 1.0 3.7 1 1 2 3 3 3 0 Calmodulin binding domain Baculo_PEP_C PF04513.12 ORZ01526.1 - 4.5 7.3 6.3 1.5 8.9 0.8 2.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 ORZ01526.1 - 6.2 5.2 8.2 22 3.4 6.3 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 ORZ01526.1 - 6.9 7.2 12.8 18 5.9 4.0 4.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein S4 PF01479.25 ORZ01527.1 - 1.3e-12 47.2 1.0 1.3e-12 47.2 1.0 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORZ01527.1 - 1.7e-06 28.8 0.4 2.4e-06 28.4 0.4 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PseudoU_synth_1 PF01416.20 ORZ01528.1 - 2.2e-28 98.8 0.0 1.9e-26 92.6 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase GPI-anchored PF10342.9 ORZ01529.1 - 2.1e-12 47.7 0.5 8.3e-12 45.7 0.5 2.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Aldedh PF00171.22 ORZ01530.1 - 7.4e-89 298.4 0.0 9.2e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Med8 PF10232.9 ORZ01531.1 - 1.3e-06 28.2 7.1 4.1e-06 26.6 7.1 1.8 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Abi_2 PF07751.11 ORZ01531.1 - 0.0031 17.8 2.0 0.0045 17.3 2.0 1.3 1 0 0 1 1 1 1 Abi-like protein Mit_KHE1 PF10173.9 ORZ01531.1 - 0.48 10.5 4.5 0.81 9.7 4.5 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Presenilin PF01080.17 ORZ01531.1 - 1.8 7.2 6.6 2.3 6.9 6.6 1.2 1 0 0 1 1 1 0 Presenilin Far-17a_AIG1 PF04750.14 ORZ01532.1 - 3e-31 108.3 14.0 3.4e-31 108.1 14.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein RasGEF PF00617.19 ORZ01533.1 - 1.5e-42 145.8 0.0 3.9e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain FAT PF02259.23 ORZ01533.1 - 0.073 12.3 0.2 8.1 5.5 0.0 2.2 2 0 0 2 2 2 0 FAT domain DUF1771 PF08590.10 ORZ01534.1 - 4e-21 75.2 17.7 1.1e-19 70.6 12.6 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1771) Smr PF01713.21 ORZ01534.1 - 2.4e-10 40.6 1.3 6.4e-10 39.2 0.0 2.5 2 2 0 2 2 2 1 Smr domain EF-hand_1 PF00036.32 ORZ01536.1 - 2.6e-39 129.9 10.8 8.1e-10 37.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORZ01536.1 - 5.8e-30 103.6 7.8 9.8e-19 67.6 0.9 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORZ01536.1 - 3.2e-28 95.2 9.2 2.7e-09 36.2 0.0 4.7 5 1 0 5 5 4 4 EF-hand domain EF-hand_8 PF13833.6 ORZ01536.1 - 9.1e-27 92.7 13.4 3.8e-15 55.5 0.4 4.8 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 ORZ01536.1 - 5e-24 82.7 9.0 2.7e-06 26.6 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORZ01536.1 - 2.2e-10 40.7 0.1 0.0038 17.5 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 ORZ01536.1 - 1.7e-07 31.1 4.6 8.4e-05 22.5 0.3 3.1 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORZ01536.1 - 5e-07 30.0 1.1 0.00016 22.0 0.1 2.8 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 ORZ01536.1 - 0.00015 21.7 0.5 0.00015 21.7 0.5 2.2 3 0 0 3 3 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 ORZ01536.1 - 0.001 19.2 1.1 0.7 10.1 0.8 3.4 2 1 1 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 ORZ01536.1 - 0.0014 18.6 1.0 0.71 9.8 0.0 3.3 2 1 2 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 ORZ01536.1 - 0.0015 17.2 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 ORZ01536.1 - 0.0015 18.4 0.6 0.0076 16.1 0.3 2.0 2 0 0 2 2 2 1 SurA N-terminal domain DUF3349 PF11829.8 ORZ01536.1 - 0.0074 17.0 1.3 11 6.9 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_11 PF08976.11 ORZ01536.1 - 0.0082 17.0 0.1 0.017 16.0 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain DUF4834 PF16118.5 ORZ01536.1 - 0.0083 17.1 0.1 0.024 15.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) UPF0154 PF03672.13 ORZ01536.1 - 0.0085 16.1 0.2 0.1 12.6 0.0 2.8 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0154) RPN13_C PF16550.5 ORZ01536.1 - 0.035 14.3 0.1 3.8 7.7 0.0 2.3 2 1 0 2 2 2 0 UCH-binding domain YqeY PF09424.10 ORZ01536.1 - 0.056 13.5 3.2 0.34 11.0 1.2 2.1 2 0 0 2 2 2 0 Yqey-like protein DUF4497 PF14924.6 ORZ01536.1 - 0.084 13.4 0.0 0.89 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Amdo_NSP PF12475.8 ORZ01536.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Amdovirus non-structural protein DUF2267 PF10025.9 ORZ01536.1 - 0.18 12.1 0.3 0.99 9.7 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) TerB PF05099.13 ORZ01536.1 - 0.27 11.2 3.3 3.4 7.6 0.1 2.8 2 1 1 3 3 3 0 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 ORZ01536.1 - 0.34 11.2 2.7 1.2 9.5 0.2 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 Fe_hyd_lg_C PF02906.14 ORZ01536.1 - 0.62 9.7 2.4 2.5 7.7 0.1 2.2 2 1 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain ADIP PF11559.8 ORZ01537.1 - 0.056 13.5 1.8 0.12 12.4 1.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DNA_pol_phi PF04931.13 ORZ01537.1 - 7.6 4.5 30.7 14 3.7 30.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi SANT_DAMP1_like PF16282.5 ORZ01538.1 - 3.7e-25 87.9 2.5 3.7e-25 87.9 2.5 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 ORZ01538.1 - 0.004 17.1 9.5 0.021 14.7 9.5 2.1 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) APG6_N PF17675.1 ORZ01538.1 - 0.007 16.9 6.4 0.017 15.7 6.4 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF2252 PF10009.9 ORZ01538.1 - 0.66 9.0 5.8 1.1 8.3 5.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Sec39 PF08314.11 ORZ01539.1 - 1.2e-81 275.3 1.8 2.9e-79 267.4 0.6 2.1 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Pex24p PF06398.11 ORZ01540.1 - 9.2e-38 130.2 6.8 1.2e-37 129.8 6.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PBP1_TM PF14812.6 ORZ01540.1 - 9.4 6.7 12.9 32 5.0 12.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_I_A49 PF06870.12 ORZ01541.1 - 2e-94 316.6 4.3 2.3e-94 316.4 4.3 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor IL15 PF02372.15 ORZ01541.1 - 0.11 12.4 0.5 0.25 11.3 0.5 1.5 1 0 0 1 1 1 0 Interleukin 15 F-box PF00646.33 ORZ01542.1 - 0.018 14.9 1.6 0.031 14.1 1.6 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORZ01542.1 - 0.028 14.3 0.6 0.052 13.4 0.6 1.5 1 0 0 1 1 1 0 F-box-like Nup88 PF10168.9 ORZ01543.1 - 1.5e-23 82.5 18.1 4.8e-12 44.5 0.0 2.7 2 1 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 ORZ01543.1 - 4.5e-05 23.6 8.2 4.5e-05 23.6 8.2 2.3 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 AAA_23 PF13476.6 ORZ01543.1 - 5.1 7.6 8.6 12 6.4 8.6 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORZ01544.1 - 3e-14 53.1 0.0 1.9e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORZ01544.1 - 3.6e-09 36.8 0.0 6.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 ORZ01544.1 - 2.5e-06 27.1 0.1 2.7e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 ORZ01544.1 - 0.00012 21.3 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 ORZ01544.1 - 0.00044 19.6 0.0 0.00097 18.5 0.0 1.5 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 ORZ01544.1 - 0.0029 17.7 0.4 0.29 11.2 0.1 2.4 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 ORZ01544.1 - 0.013 15.9 0.4 0.22 11.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 ORZ01544.1 - 0.02 14.4 0.1 1.7 8.2 0.0 3.4 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain Roc PF08477.13 ORZ01544.1 - 0.048 13.9 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 ORZ01544.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 ORZ01544.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RabGAP-TBC PF00566.18 ORZ01545.1 - 7.4e-42 143.4 0.0 1.5e-41 142.5 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain ADH_zinc_N PF00107.26 ORZ01547.1 - 2.2e-28 98.8 0.2 3.9e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ01547.1 - 2.8e-18 67.3 0.1 6.1e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORZ01547.1 - 1.3e-08 34.7 0.0 6.4e-08 32.4 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORZ01547.1 - 0.082 13.2 0.1 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain DUF4112 PF13430.6 ORZ01548.1 - 3.5e-27 94.7 0.6 5.6e-27 94.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AIG1 PF04548.16 ORZ01548.1 - 0.026 13.8 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 AIG1 family MgtE PF01769.16 ORZ01548.1 - 0.041 14.3 1.6 0.072 13.5 1.6 1.4 1 0 0 1 1 1 0 Divalent cation transporter DUF935 PF06074.12 ORZ01548.1 - 0.061 12.1 0.2 0.11 11.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF935) T2SSK PF03934.13 ORZ01548.1 - 0.1 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K PhoR PF11808.8 ORZ01548.1 - 1.4 9.4 5.4 0.95 9.9 0.3 3.0 2 1 2 4 4 4 0 Phosphate regulon sensor protein PhoR Band_7 PF01145.25 ORZ01549.1 - 2.3e-32 112.4 1.8 2.3e-32 112.4 1.8 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORZ01549.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Band_7 PF01145.25 ORZ01551.1 - 5.2e-30 104.8 0.5 6.4e-30 104.5 0.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORZ01551.1 - 0.0013 18.5 0.1 0.0021 17.8 0.1 1.4 1 1 0 1 1 1 1 SPFH domain-Band 7 family Per1 PF04080.13 ORZ01554.1 - 2.5e-84 283.0 9.2 2.5e-84 283.0 9.2 1.8 2 0 0 2 2 2 1 Per1-like family NAD_binding_8 PF13450.6 ORZ01554.1 - 6.4e-14 51.9 0.0 1.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORZ01554.1 - 5.3e-09 35.9 0.0 6e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ORZ01554.1 - 6.3e-06 26.3 0.1 0.093 12.7 0.0 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 ORZ01554.1 - 0.0011 18.6 0.0 0.0058 16.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORZ01554.1 - 0.0049 16.1 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORZ01554.1 - 0.017 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 ORZ01554.1 - 0.094 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DUF4807 PF16065.5 ORZ01555.1 - 2.1e-23 82.3 0.5 2.7e-23 82.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) Bin3 PF06859.12 ORZ01555.1 - 0.069 13.8 0.0 0.098 13.3 0.0 1.2 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Ribosomal_L6e PF01159.19 ORZ01556.1 - 8.9e-36 122.8 0.1 3.3e-35 121.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.29 ORZ01556.1 - 0.0025 17.7 0.1 0.018 15.0 0.1 2.3 2 0 0 2 2 2 1 KOW motif U-box PF04564.15 ORZ01556.1 - 0.081 13.1 0.0 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 U-box domain Mito_carr PF00153.27 ORZ01557.1 - 6.9e-54 179.8 10.1 8.7e-20 70.5 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 ORZ01557.1 - 0.00082 18.6 2.4 0.038 13.1 0.2 2.9 2 1 1 3 3 3 2 Gammaproteobacterial serine protease DUF5518 PF17647.1 ORZ01557.1 - 1.1 9.4 8.0 0.54 10.4 1.6 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5518) tRNA_U5-meth_tr PF05958.11 ORZ01558.1 - 1.9e-13 50.1 1.3 1.9e-13 50.1 1.3 2.5 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 ORZ01558.1 - 7.4e-10 38.8 0.1 1.7e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 ORZ01558.1 - 1.2e-07 31.5 0.4 5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 ORZ01558.1 - 2.3e-07 30.5 0.1 4.4e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 ORZ01558.1 - 3.3e-07 30.1 0.7 6.3e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 ORZ01558.1 - 1.5e-06 28.8 0.0 4.9e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORZ01558.1 - 3.1e-05 23.8 0.2 9e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 ORZ01558.1 - 6.6e-05 22.4 0.1 0.00019 21.0 0.1 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 ORZ01558.1 - 0.00014 21.9 2.4 0.0082 16.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORZ01558.1 - 0.00031 20.3 1.3 0.00031 20.3 1.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) RRM_1 PF00076.22 ORZ01558.1 - 0.0027 17.5 0.1 0.0067 16.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ubie_methyltran PF01209.18 ORZ01558.1 - 0.01 15.2 0.3 0.02 14.2 0.3 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.8 ORZ01558.1 - 0.024 14.1 1.3 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_11 PF08241.12 ORZ01558.1 - 0.061 14.0 0.1 0.16 12.6 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 ORZ01558.1 - 0.084 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Fez1 PF06818.15 ORZ01558.1 - 0.39 11.1 12.4 0.21 12.0 9.9 1.8 2 0 0 2 2 2 0 Fez1 DUF3523 PF12037.8 ORZ01558.1 - 8 5.7 15.0 16 4.8 15.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) C2 PF00168.30 ORZ01559.1 - 4.1e-14 52.7 0.0 1e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 C2 domain PAP_PilO PF06864.12 ORZ01559.1 - 0.047 12.5 0.2 0.047 12.5 0.2 1.5 2 0 0 2 2 1 0 Pilin accessory protein (PilO) LicD PF04991.13 ORZ01559.1 - 0.067 13.3 0.9 0.096 12.8 0.9 1.3 1 0 0 1 1 1 0 LicD family HemX PF04375.14 ORZ01559.1 - 0.079 12.2 7.5 0.11 11.7 7.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4192 PF13830.6 ORZ01559.1 - 0.083 12.9 5.3 0.11 12.6 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RR_TM4-6 PF06459.12 ORZ01559.1 - 0.099 12.5 12.3 0.14 12.0 12.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 ORZ01559.1 - 0.25 11.4 14.2 0.35 10.9 14.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MAP7 PF05672.11 ORZ01559.1 - 0.26 11.0 42.3 0.4 10.3 42.3 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF533 PF04391.12 ORZ01559.1 - 0.29 10.7 6.2 0.28 10.7 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF533) G6B PF15096.6 ORZ01559.1 - 0.3 10.9 1.1 0.49 10.2 0.7 1.5 1 1 0 1 1 1 0 G6B family Hid1 PF12722.7 ORZ01559.1 - 0.46 8.6 7.1 0.53 8.3 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 ORZ01559.1 - 0.47 10.5 2.9 0.61 10.1 2.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region U79_P34 PF03064.16 ORZ01559.1 - 0.72 9.2 20.7 1.7 7.9 20.7 1.6 1 1 0 1 1 1 0 HSV U79 / HCMV P34 AAA_11 PF13086.6 ORZ01559.1 - 1.2 8.8 10.3 1.6 8.5 10.3 1.2 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 ORZ01559.1 - 1.3 8.2 11.7 1.8 7.7 11.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Atg14 PF10186.9 ORZ01559.1 - 1.4 8.0 10.6 1.7 7.7 10.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VIT1 PF01988.19 ORZ01559.1 - 1.6 8.5 4.8 2.8 7.7 4.8 1.3 1 0 0 1 1 1 0 VIT family HSP70 PF00012.20 ORZ01559.1 - 2.1 6.4 13.8 2.9 6.0 13.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Pinin_SDK_memA PF04696.13 ORZ01559.1 - 3.1 7.9 33.0 5.2 7.1 33.0 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region MAJIN PF15077.6 ORZ01559.1 - 3.3 7.4 9.9 5.1 6.8 9.9 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Dsh_C PF12316.8 ORZ01559.1 - 7.1 7.0 6.7 11 6.4 6.7 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal XRN_M PF17846.1 ORZ01559.1 - 9.2 5.1 12.5 15 4.4 12.5 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 ORZ01559.1 - 9.5 4.9 19.2 13 4.4 19.2 1.1 1 0 0 1 1 1 0 Presenilin Sdh_cyt PF01127.22 ORZ01560.1 - 5.9e-24 84.4 2.6 7.9e-24 84.0 2.6 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MOZ_SAS PF01853.18 ORZ01561.1 - 3e-84 281.1 0.3 4.5e-84 280.6 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORZ01561.1 - 1.1e-22 79.3 7.4 3.5e-22 77.8 7.4 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 ORZ01561.1 - 7.9e-19 67.3 0.7 1.8e-18 66.1 0.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 ORZ01561.1 - 0.0025 18.2 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORZ01561.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TFIIE_beta PF02186.15 ORZ01561.1 - 0.032 14.5 0.4 0.18 12.1 0.1 2.3 3 0 0 3 3 3 0 TFIIE beta subunit core domain HTH_11 PF08279.12 ORZ01561.1 - 0.1 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 HTH domain Response_reg PF00072.24 ORZ01562.1 - 1.2e-17 64.0 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Autophagy_N PF03986.13 ORZ01563.1 - 2.8e-46 156.9 0.4 4.3e-46 156.3 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 ORZ01563.1 - 1.7e-20 73.4 0.4 4.5e-20 72.0 0.4 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 ORZ01563.1 - 3.1e-15 55.4 3.2 5.9e-15 54.5 3.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal RRP7 PF12923.7 ORZ01563.1 - 0.16 12.1 1.3 0.3 11.2 1.3 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PGM_PMM_I PF02878.16 ORZ01564.1 - 4e-36 123.8 0.1 5.9e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ORZ01564.1 - 1.8e-28 99.0 0.0 3.8e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORZ01564.1 - 6.6e-16 58.8 0.0 1.9e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORZ01564.1 - 2.9e-07 30.5 0.0 8.6e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glycos_transf_2 PF00535.26 ORZ01565.1 - 0.0067 16.2 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 ribosomal_L24 PF17136.4 ORZ01566.1 - 3.2e-12 46.7 0.1 7.6e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 ORZ01566.1 - 2.4e-05 24.1 0.8 5e-05 23.1 0.8 1.6 1 0 0 1 1 1 1 KOW motif AMP-binding PF00501.28 ORZ01569.1 - 1.1e-66 225.3 0.0 1.7e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ01569.1 - 3.5e-11 43.9 0.2 7.8e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 ORZ01569.1 - 0.036 14.4 0.5 0.11 12.9 0.5 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain WD40 PF00400.32 ORZ01570.1 - 1.6e-51 171.1 18.6 2.1e-06 28.3 0.0 11.7 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ01570.1 - 2.1e-23 82.5 3.7 2e-05 24.8 0.0 7.0 5 3 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 ORZ01570.1 - 3.1e-20 72.5 2.5 6.6e-20 71.4 2.5 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 ORZ01570.1 - 1.4e-06 27.9 0.1 0.39 10.0 0.0 5.1 5 2 0 5 5 5 2 WD40-like domain eIF2A PF08662.11 ORZ01570.1 - 1.8e-06 28.0 0.1 0.0017 18.2 0.0 3.6 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORZ01570.1 - 6.6e-06 25.0 3.2 0.67 8.5 0.1 4.6 4 1 0 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORZ01570.1 - 4.8e-05 22.5 1.1 2.4 7.1 0.0 5.2 4 2 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORZ01570.1 - 0.0067 15.0 0.3 0.039 12.5 0.0 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain Utp13 PF08625.11 ORZ01570.1 - 0.091 12.7 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain ELYS-bb PF16687.5 ORZ01570.1 - 0.1 11.2 0.1 1.5 7.3 0.0 2.7 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin SIR2 PF02146.17 ORZ01571.1 - 4.3e-39 134.3 0.0 5.6e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family WD40 PF00400.32 ORZ01572.1 - 2.1e-11 44.1 9.2 0.00029 21.6 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat SAM_2 PF07647.17 ORZ01573.1 - 3.6e-06 27.0 0.2 9.5e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORZ01573.1 - 0.00016 22.0 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 ORZ01573.1 - 0.023 14.8 0.2 0.058 13.5 0.2 1.7 1 0 0 1 1 1 0 IGR protein motif Pilus_CpaD PF09476.10 ORZ01573.1 - 0.46 10.2 8.2 0.14 11.9 1.8 2.4 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Roughex PF06020.11 ORZ01573.1 - 1.7 7.7 7.3 4.5 6.3 2.4 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Spt20 PF12090.8 ORZ01573.1 - 2.1 7.9 12.6 6.3 6.3 1.1 2.4 2 0 0 2 2 2 0 Spt20 family Ins_P5_2-kin PF06090.12 ORZ01574.1 - 1.1e-71 241.9 0.0 1.3e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Metallophos PF00149.28 ORZ01575.1 - 2.6e-39 135.8 0.1 3.3e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORZ01575.1 - 6.6e-22 77.7 1.0 1.2e-21 76.8 0.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain CCDC144C PF14915.6 ORZ01576.1 - 0.00012 21.3 2.2 0.00015 21.0 2.2 1.0 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Rootletin PF15035.6 ORZ01576.1 - 0.052 13.6 2.7 0.071 13.1 2.7 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Amidohydro_1 PF01979.20 ORZ01577.1 - 3.1e-35 122.1 0.0 4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORZ01577.1 - 4.4e-13 49.5 0.3 7.9e-08 32.2 0.0 2.4 3 0 0 3 3 3 2 Amidohydrolase family VirB8 PF04335.13 ORZ01577.1 - 0.12 12.2 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 VirB8 protein Pkinase PF00069.25 ORZ01578.1 - 2.6e-22 79.4 0.0 3.6e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01578.1 - 3.6e-07 29.7 0.0 5.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF905 PF06006.12 ORZ01578.1 - 0.14 12.1 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Pkinase PF00069.25 ORZ01579.1 - 0.00018 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORZ01579.1 - 0.027 14.4 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 ORZ01579.1 - 0.054 12.8 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Aim19 PF10315.9 ORZ01580.1 - 7.5e-31 106.8 4.2 8.8e-31 106.6 4.2 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Tmemb_14 PF03647.13 ORZ01580.1 - 1.5e-05 25.6 1.0 2.5e-05 24.9 1.0 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C DNA_pol_phi PF04931.13 ORZ01581.1 - 8.3e-189 629.4 8.8 8.3e-189 629.4 8.8 1.6 2 0 0 2 2 2 1 DNA polymerase phi His_kinase PF06580.13 ORZ01581.1 - 0.0043 17.4 0.2 6.5 7.2 0.0 3.3 3 0 0 3 3 3 2 Histidine kinase Adaptin_N PF01602.20 ORZ01581.1 - 0.021 13.4 1.3 1.9 6.9 0.0 3.9 4 2 0 4 4 4 0 Adaptin N terminal region BUD22 PF09073.10 ORZ01581.1 - 0.16 11.3 13.8 0.34 10.2 13.8 1.5 1 0 0 1 1 1 0 BUD22 PPR_2 PF13041.6 ORZ01581.1 - 0.17 12.1 0.1 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 PPR repeat family Spt5_N PF11942.8 ORZ01581.1 - 1.6 9.8 27.2 8.4 7.4 27.2 2.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SDA1 PF05285.12 ORZ01581.1 - 1.9 7.8 18.7 4 6.8 18.7 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 ORZ01581.1 - 2 6.6 16.0 4.1 5.6 16.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 ORZ01581.1 - 5.3 5.0 6.5 8.9 4.3 6.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nramp PF01566.18 ORZ01583.1 - 7.4e-111 370.6 18.2 1.1e-110 370.0 18.2 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein TB2_DP1_HVA22 PF03134.19 ORZ01584.1 - 9.6e-31 105.5 5.8 9.6e-31 105.5 5.8 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Peptidase_M76 PF09768.9 ORZ01585.1 - 1.7e-72 242.7 5.1 2.2e-72 242.4 5.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family DnaJ PF00226.31 ORZ01586.1 - 3.4e-22 78.3 4.2 5.8e-22 77.6 4.2 1.4 1 0 0 1 1 1 1 DnaJ domain Helicase_C PF00271.31 ORZ01589.1 - 3.1e-10 40.4 0.1 5.3e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORZ01590.1 - 4.4e-50 169.9 0.0 5.4e-49 166.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ01590.1 - 1.8e-16 60.5 0.0 1.2e-15 57.8 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ01590.1 - 1.6e-05 25.0 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORZ01590.1 - 0.0098 16.2 0.0 1.6 9.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Takusan PF04822.13 ORZ01590.1 - 0.13 12.2 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Takusan AAA_22 PF13401.6 ORZ01590.1 - 0.16 12.2 0.9 4.4 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF2443 PF10398.9 ORZ01590.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Ricin_B_lectin PF00652.22 ORZ01591.1 - 8.8e-51 171.4 12.2 1.9e-05 24.9 0.3 14.4 10 4 5 15 15 15 9 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ORZ01591.1 - 3.8e-22 78.8 21.0 0.0062 17.2 0.1 12.1 8 3 2 11 11 11 8 Ricin-type beta-trefoil lectin domain-like Spore_GerQ PF09671.10 ORZ01591.1 - 0.00024 21.1 0.3 8.4 6.5 0.0 3.6 3 0 0 3 3 3 2 Spore coat protein (Spore_GerQ) ATE_C PF04377.15 ORZ01591.1 - 0.00052 20.7 4.6 3.1 8.4 0.0 5.8 6 0 0 6 6 6 1 Arginine-tRNA-protein transferase, C terminus SAF PF08666.12 ORZ01591.1 - 0.029 15.0 0.5 0.22 12.2 0.5 2.7 1 0 0 1 1 1 0 SAF domain GTP_EFTU_D3 PF03143.17 ORZ01591.1 - 0.25 11.7 3.7 14 6.0 0.3 4.2 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain DUF1825 PF08855.10 ORZ01591.1 - 0.47 10.4 4.0 67 3.5 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) ADSL_C PF10397.9 ORZ01591.1 - 1.8 9.2 11.1 11 6.6 0.3 5.5 5 0 0 5 5 5 0 Adenylosuccinate lyase C-terminus CMD PF02627.20 ORZ01591.1 - 3.3 7.8 6.8 9.5 6.4 0.1 5.1 4 0 0 4 4 4 0 Carboxymuconolactone decarboxylase family SfLAP PF11139.8 ORZ01591.1 - 7 6.0 6.3 24 4.3 0.1 5.1 8 0 0 8 8 8 0 Sap, sulfolipid-1-addressing protein Hydrolase_4 PF12146.8 ORZ01592.1 - 1.2e-13 50.9 0.0 6.6e-08 32.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORZ01592.1 - 1e-05 25.3 0.2 0.061 13.0 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ORZ01592.1 - 0.00073 19.4 0.1 0.022 14.6 0.0 2.3 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORZ01592.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 ORZ01592.1 - 0.0018 17.8 0.0 0.0098 15.4 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORZ01592.1 - 0.008 15.7 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORZ01592.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORZ01592.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Elong_Iki1 PF10483.9 ORZ01593.1 - 1.5e-21 77.2 0.0 1.7e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 TPT PF03151.16 ORZ01595.1 - 9.6e-21 74.4 8.7 1.1e-20 74.2 8.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORZ01595.1 - 2e-10 41.0 21.3 5.9e-08 33.0 9.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORZ01595.1 - 0.0001 21.6 10.1 0.00013 21.3 10.1 1.2 1 0 0 1 1 1 1 UAA transporter family DUF4229 PF14012.6 ORZ01595.1 - 0.11 12.6 4.2 0.092 12.9 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Beta-APP PF03494.13 ORZ01595.1 - 0.3 10.9 3.8 0.85 9.5 3.8 1.8 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Phage_holin_2_4 PF16082.5 ORZ01595.1 - 2.3 8.0 4.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like COPIIcoated_ERV PF07970.12 ORZ01597.1 - 1.8e-39 135.9 0.5 3.3e-39 135.0 0.5 1.3 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORZ01597.1 - 1.6e-21 76.4 0.0 3.5e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2040 PF09745.9 ORZ01597.1 - 0.013 15.6 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) MFS_1 PF07690.16 ORZ01598.1 - 3.9e-28 98.4 44.6 3.9e-28 98.4 44.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S16 PF00886.19 ORZ01599.1 - 2.3e-28 98.0 0.1 3e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RicinB_lectin_2 PF14200.6 ORZ01600.1 - 4.3e-05 24.1 5.2 0.023 15.4 0.0 3.8 3 2 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like AtuA PF07287.11 ORZ01602.1 - 5.8e-114 380.5 0.0 7.3e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA KH_1 PF00013.29 ORZ01603.1 - 5.1e-29 99.9 0.0 3.4e-08 33.2 0.0 6.9 7 0 0 7 7 7 5 KH domain PhageMin_Tail PF10145.9 ORZ01603.1 - 0.01 15.7 1.0 0.022 14.6 1.0 1.5 1 0 0 1 1 1 0 Phage-related minor tail protein SLS PF14611.6 ORZ01603.1 - 0.019 14.8 0.0 8.8 6.1 0.0 3.0 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator Evr1_Alr PF04777.13 ORZ01604.1 - 5.3e-29 100.6 2.0 5.3e-29 100.6 2.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family DUF3157 PF11355.8 ORZ01604.1 - 0.026 14.1 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) O-FucT PF10250.9 ORZ01605.1 - 8.4e-13 48.7 0.0 7.1e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase GTP_EFTU PF00009.27 ORZ01606.1 - 3.5e-46 157.2 0.2 7e-46 156.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORZ01606.1 - 1.5e-21 76.8 0.1 1.5e-21 76.8 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 ORZ01606.1 - 5.7e-05 23.2 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORZ01606.1 - 0.0011 19.3 0.3 0.0011 19.3 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 ORZ01606.1 - 0.002 18.0 0.1 0.0079 16.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 YdfZ PF14001.6 ORZ01606.1 - 0.0067 16.8 0.1 0.02 15.3 0.1 1.8 1 0 0 1 1 1 1 YdfZ protein AAA_22 PF13401.6 ORZ01606.1 - 0.0094 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 ORZ01606.1 - 0.024 14.3 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Ras family Roc PF08477.13 ORZ01606.1 - 0.063 13.5 0.0 10 6.3 0.0 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NUC194 PF08163.12 ORZ01606.1 - 0.23 10.4 1.3 0.34 9.8 1.3 1.1 1 0 0 1 1 1 0 NUC194 domain Dynamin_N PF00350.23 ORZ01606.1 - 0.31 11.1 3.0 10 6.2 0.0 3.2 2 1 1 3 3 3 0 Dynamin family IHABP4_N PF16174.5 ORZ01606.1 - 3 8.4 11.8 5.5 7.6 11.8 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SPATA3 PF15662.5 ORZ01606.1 - 4.8 7.8 11.4 7.1 7.2 11.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family RhoGEF PF00621.20 ORZ01607.1 - 5.8e-34 117.9 2.0 9.8e-34 117.2 2.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 ORZ01607.1 - 0.00043 20.8 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Complex1_LYR PF05347.15 ORZ01608.1 - 3.4e-10 39.8 0.2 6.1e-10 39.0 0.2 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORZ01608.1 - 4.8e-07 30.4 0.2 6e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like MIX PF18529.1 ORZ01608.1 - 0.023 14.4 0.1 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins Ribosomal_S11 PF00411.19 ORZ01609.1 - 2.6e-47 159.8 1.3 3.3e-47 159.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 COG7 PF10191.9 ORZ01610.1 - 4e-84 283.3 15.6 1.1e-53 182.6 7.5 3.0 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) Vps54_N PF10475.9 ORZ01610.1 - 0.00018 20.9 1.1 0.00045 19.6 1.1 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG4 PF08318.12 ORZ01610.1 - 0.0007 18.8 0.3 0.0028 16.8 0.0 2.2 2 0 0 2 2 2 1 COG4 transport protein DUF1770 PF08589.10 ORZ01611.1 - 0.047 14.7 0.1 0.065 14.2 0.1 1.2 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) MTS PF05175.14 ORZ01612.1 - 2.3e-06 27.3 0.0 6.3e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 ORZ01612.1 - 0.0032 17.3 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ORZ01612.1 - 0.0066 17.1 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORZ01612.1 - 0.021 14.2 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 ORZ01612.1 - 0.032 15.3 0.0 0.07 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORZ01612.1 - 0.041 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Clr5 PF14420.6 ORZ01612.1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Clr5 domain DAHP_synth_1 PF00793.20 ORZ01613.1 - 4.1e-104 347.3 0.0 5.1e-104 347.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family tRNA-synt_1b PF00579.25 ORZ01614.1 - 5e-70 236.1 0.0 6.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PQ-loop PF04193.14 ORZ01616.1 - 1.8e-36 123.7 10.5 2.6e-18 65.5 0.5 2.7 2 0 0 2 2 2 2 PQ loop repeat LAB_N PF07578.11 ORZ01616.1 - 0.016 15.2 0.5 2.7 8.1 0.0 3.1 3 0 0 3 3 3 0 Lipid A Biosynthesis N-terminal domain MtN3_slv PF03083.16 ORZ01616.1 - 0.018 15.1 0.1 0.018 15.1 0.1 2.4 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange HMG_box PF00505.19 ORZ01619.1 - 1.8e-20 73.1 6.3 8e-11 42.2 2.5 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ01619.1 - 1.5e-11 44.7 6.6 6.4e-07 29.9 2.8 2.9 2 0 0 2 2 2 2 HMG-box domain CTP_transf_3 PF02348.19 ORZ01619.1 - 0.01 15.8 1.7 0.025 14.5 1.7 1.7 1 0 0 1 1 1 0 Cytidylyltransferase CHDNT PF08073.12 ORZ01619.1 - 0.12 12.4 0.4 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 CHDNT (NUC034) domain RasGAP PF00616.19 ORZ01620.1 - 8e-56 189.0 0.0 2.1e-55 187.7 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORZ01620.1 - 3.3e-38 130.9 3.5 3.3e-38 130.9 3.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus TPR_MLP1_2 PF07926.12 ORZ01620.1 - 0.035 14.2 0.5 0.035 14.2 0.5 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3800 PF12686.7 ORZ01620.1 - 0.09 13.4 0.2 0.73 10.5 0.2 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Methyltransf_32 PF13679.6 ORZ01620.1 - 0.13 12.3 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain CTK3 PF12243.8 ORZ01620.1 - 0.19 11.7 2.2 5.5 7.0 0.0 3.2 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 UPF0220 PF05255.11 ORZ01621.1 - 9e-55 184.7 4.2 1.1e-54 184.5 4.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Ribosomal_L7Ae PF01248.26 ORZ01622.1 - 3.8e-23 81.0 1.3 6.2e-23 80.3 0.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 ORZ01622.1 - 0.0061 16.5 0.9 0.011 15.7 0.9 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNase_P_pop3 PF08228.11 ORZ01622.1 - 0.013 15.6 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 HIN PF02760.15 ORZ01622.1 - 0.027 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 HIN-200/IF120x domain KAP_NTPase PF07693.14 ORZ01622.1 - 0.034 13.4 0.2 0.076 12.2 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain Fungal_trans PF04082.18 ORZ01623.1 - 1e-11 44.4 2.1 1e-11 44.4 2.1 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Phage_holin_4_1 PF05105.12 ORZ01623.1 - 0.11 12.7 0.1 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family Aminotran_4 PF01063.19 ORZ01625.1 - 8.6e-20 71.6 0.0 1.1e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF2407 PF10302.9 ORZ01625.1 - 0.0029 18.1 0.1 0.0042 17.6 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain tRNA_lig_CPD PF08302.11 ORZ01625.1 - 0.059 12.8 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Abhydrolase_3 PF07859.13 ORZ01626.1 - 3.6e-21 76.0 0.0 5.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORZ01626.1 - 0.1 11.8 0.0 0.41 9.9 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORZ01626.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase E1_DerP2_DerF2 PF02221.15 ORZ01627.1 - 3.5e-22 79.3 0.3 4.7e-22 78.9 0.3 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 ORZ01627.1 - 0.00011 22.6 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 ORZ01628.1 - 1.2e-18 67.8 0.1 1.5e-18 67.5 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 ORZ01628.1 - 0.00014 22.2 0.0 0.0002 21.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Asp PF00026.23 ORZ01629.1 - 1.6e-85 287.3 0.0 1.9e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORZ01629.1 - 2.2e-17 63.8 2.4 5.2e-08 33.3 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ORZ01629.1 - 0.0025 18.3 0.0 2.3 8.8 0.0 3.0 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORZ01629.1 - 0.0042 17.7 0.2 0.44 11.2 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease F-box-like PF12937.7 ORZ01630.1 - 1.7e-06 27.8 0.2 5.8e-06 26.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORZ01630.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 ORZ01630.1 - 0.12 12.8 6.1 21 5.7 0.2 4.5 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) PDEase_I PF00233.19 ORZ01631.1 - 2.5e-76 256.5 0.0 3.6e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 ORZ01631.1 - 0.013 15.7 0.1 0.038 14.2 0.1 1.9 1 0 0 1 1 1 0 HD domain STAG PF08514.11 ORZ01632.1 - 6.8e-26 90.4 1.8 1.7e-25 89.1 0.4 2.4 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 ORZ01632.1 - 0.00053 20.0 0.5 2.6 8.5 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat RasGEF_N PF00618.20 ORZ01632.1 - 0.014 15.6 1.8 8.9 6.6 0.0 4.1 3 1 1 4 4 4 0 RasGEF N-terminal motif FlbT PF07378.11 ORZ01632.1 - 0.45 10.6 5.3 4.4 7.4 0.0 4.2 4 0 0 4 4 4 0 Flagellar protein FlbT ParBc_2 PF08857.11 ORZ01633.1 - 0.09 12.9 0.2 0.28 11.3 0.1 1.8 2 0 0 2 2 2 0 Putative ParB-like nuclease Pkinase PF00069.25 ORZ01634.1 - 9.9e-71 238.2 0.0 1.2e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01634.1 - 3.3e-52 177.3 0.0 5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ01634.1 - 5.7e-05 22.1 0.0 8.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORZ01634.1 - 0.00013 21.4 0.1 0.0059 16.0 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORZ01634.1 - 0.0015 17.5 0.0 0.75 8.7 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain DUF3984 PF13136.6 ORZ01635.1 - 0.0041 16.6 4.1 0.0045 16.4 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) UDPG_MGDP_dh_C PF03720.15 ORZ01635.1 - 0.04 14.3 0.6 0.065 13.7 0.6 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF1241 PF06840.11 ORZ01635.1 - 0.056 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DUF3292 PF11696.8 ORZ01635.1 - 0.057 11.8 4.7 0.062 11.7 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Cucumo_2B PF03263.13 ORZ01635.1 - 0.14 12.6 1.2 0.19 12.2 1.0 1.4 1 1 0 1 1 1 0 Cucumovirus protein 2B HHH_2 PF12826.7 ORZ01637.1 - 0.043 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Hydantoinase_B PF02538.14 ORZ01638.1 - 9.4e-222 737.0 0.2 1.3e-221 736.5 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORZ01638.1 - 2.2e-103 345.5 0.5 1.8e-102 342.5 0.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORZ01638.1 - 9.5e-60 201.3 0.2 6.8e-58 195.3 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MIT PF04212.18 ORZ01640.1 - 1.8e-05 24.7 0.0 3.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TFIIA PF03153.13 ORZ01640.1 - 0.026 14.5 4.2 0.038 14.0 4.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gastrin PF00918.17 ORZ01640.1 - 0.27 12.2 3.0 0.58 11.1 3.0 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Spt20 PF12090.8 ORZ01640.1 - 1.2 8.6 13.6 2 8.0 13.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF747 PF05346.11 ORZ01641.1 - 1.9e-115 385.7 6.0 2.5e-115 385.3 6.0 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family VIGSSK PF14773.6 ORZ01641.1 - 0.011 15.8 0.1 0.031 14.4 0.1 1.8 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal DUF2681 PF10883.8 ORZ01641.1 - 0.1 13.0 0.2 17 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4834 PF16118.5 ORZ01641.1 - 1.8 9.6 6.0 1.8 9.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RNase_T PF00929.24 ORZ01642.1 - 0.0083 16.7 0.1 0.035 14.6 0.1 2.0 1 1 0 1 1 1 1 Exonuclease CHORD PF04968.12 ORZ01642.1 - 0.016 15.9 3.2 0.04 14.6 3.2 1.7 1 1 0 1 1 1 0 CHORD EloA-BP1 PF15870.5 ORZ01642.1 - 0.044 14.0 0.0 0.22 11.8 0.0 1.9 1 1 0 2 2 2 0 ElonginA binding-protein 1 DUF5051 PF16473.5 ORZ01642.1 - 0.12 12.4 0.0 1.2 9.1 0.0 2.2 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like HMG-CoA_red PF00368.18 ORZ01644.1 - 1.1e-144 482.1 7.6 1.4e-144 481.6 7.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 ORZ01644.1 - 9.1e-18 64.6 6.0 2.1e-17 63.4 6.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ORZ01644.1 - 4.5e-05 21.8 13.4 0.00034 18.9 13.4 2.0 1 1 0 1 1 1 1 Patched family HPIH PF13323.6 ORZ01644.1 - 0.025 14.4 0.6 0.059 13.2 0.6 1.6 1 1 0 1 1 1 0 N-terminal domain with HPIH motif Thioredoxin_13 PF18401.1 ORZ01645.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain PAP1 PF08601.10 ORZ01647.1 - 6.4e-14 52.5 0.1 6.4e-14 52.5 0.1 1.7 2 1 0 2 2 2 1 Transcription factor PAP1 PEP-utilisers_N PF05524.13 ORZ01647.1 - 0.011 15.8 1.9 0.15 12.3 1.5 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal GAS PF13851.6 ORZ01647.1 - 0.019 14.3 3.7 0.031 13.6 3.7 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IMD PF08397.11 ORZ01647.1 - 0.14 11.5 4.3 0.24 10.8 4.3 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Globin PF00042.22 ORZ01648.1 - 1.1e-07 32.4 0.0 0.00011 22.7 0.0 2.5 2 0 0 2 2 2 2 Globin Methyltransf_11 PF08241.12 ORZ01649.1 - 2.8e-08 34.3 0.0 8.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ01649.1 - 2.8e-06 27.9 0.0 7.8e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ01649.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 ORZ01649.1 - 0.0033 16.1 0.0 0.0043 15.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 ORZ01649.1 - 0.011 15.0 0.0 0.027 13.8 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORZ01649.1 - 0.021 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RsmF_methylt_CI PF17126.5 ORZ01650.1 - 0.095 12.8 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain DER1 PF04511.15 ORZ01651.1 - 9.8e-56 188.7 7.1 1.1e-55 188.5 7.1 1.0 1 0 0 1 1 1 1 Der1-like family CytB6-F_Fe-S PF08802.10 ORZ01651.1 - 1.7 8.7 5.7 0.52 10.4 0.4 2.7 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit PUF PF00806.19 ORZ01652.1 - 4.5e-62 202.4 15.5 7.7e-08 31.6 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 ORZ01652.1 - 7.2e-05 23.2 1.1 3 8.2 0.1 4.4 1 1 2 3 3 3 3 CPL (NUC119) domain LOB PF03195.14 ORZ01652.1 - 0.0041 17.7 2.1 9.7 6.8 0.1 4.4 3 2 3 6 6 6 2 Lateral organ boundaries (LOB) domain Dicty_REP PF05086.12 ORZ01653.1 - 0.17 9.8 6.5 0.19 9.7 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LSM14 PF12701.7 ORZ01654.1 - 3.6e-30 103.9 0.0 7e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 ORZ01654.1 - 2.2e-15 57.4 2.3 2.2e-15 57.4 2.3 2.9 4 0 0 4 4 4 1 FDF domain SM-ATX PF14438.6 ORZ01654.1 - 4.9e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 ORZ01654.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 LSM domain AcetylCoA_hydro PF02550.15 ORZ01655.1 - 1.4e-48 165.6 0.0 2.1e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 ORZ01655.1 - 3.6e-40 137.4 0.0 5.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Pkinase PF00069.25 ORZ01656.1 - 9.9e-73 244.7 0.0 1.2e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01656.1 - 4.8e-32 111.3 0.0 6.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ01656.1 - 2.7e-07 30.2 0.0 6.9e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORZ01656.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORZ01656.1 - 0.00026 19.9 0.1 0.00057 18.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORZ01656.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 ORZ01656.1 - 0.048 13.2 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TPR_8 PF13181.6 ORZ01656.1 - 0.059 13.6 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC2_membrane_2 PF12679.7 ORZ01657.1 - 0.015 14.6 2.0 0.018 14.4 2.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Brix PF04427.18 ORZ01658.1 - 3.5e-46 157.8 0.9 4.7e-46 157.3 0.9 1.2 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 ORZ01658.1 - 0.0023 17.4 19.1 0.0035 16.7 19.1 1.4 1 0 0 1 1 1 1 BUD22 PPL5 PF18168.1 ORZ01658.1 - 0.54 9.5 8.5 0.91 8.8 8.5 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Vfa1 PF08432.10 ORZ01658.1 - 3.5 7.9 23.5 7.5 6.8 23.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AP-5_subunit_s1 PF15001.6 ORZ01658.1 - 4 7.4 9.7 8 6.4 9.7 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 FGF-BP1 PF06473.12 ORZ01658.1 - 6.1 6.6 14.4 12 5.6 14.4 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Nop14 PF04147.12 ORZ01658.1 - 6.7 4.8 29.2 3.9 5.6 27.3 1.6 2 0 0 2 2 2 0 Nop14-like family SLC12 PF03522.15 ORZ01658.1 - 7.3 5.5 13.1 15 4.5 13.1 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Aldedh PF00171.22 ORZ01659.1 - 6.2e-182 605.2 0.2 7e-182 605.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 3HCDH PF00725.22 ORZ01659.1 - 0.063 13.9 0.0 15 6.3 0.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF1487 PF07368.11 ORZ01659.1 - 0.096 12.1 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DPBB_1 PF03330.18 ORZ01660.1 - 8.6e-11 42.0 0.0 3.1e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Lytic transglycolase Presenilin PF01080.17 ORZ01660.1 - 0.0032 16.3 3.1 0.0035 16.2 3.1 1.1 1 0 0 1 1 1 1 Presenilin PPP4R2 PF09184.11 ORZ01660.1 - 0.0051 16.4 8.9 0.0069 16.0 8.9 1.1 1 0 0 1 1 1 1 PPP4R2 Utp14 PF04615.13 ORZ01660.1 - 0.0055 15.4 7.1 0.0064 15.1 7.1 1.0 1 0 0 1 1 1 1 Utp14 protein Spem1 PF15670.5 ORZ01660.1 - 0.017 14.8 4.6 0.024 14.2 4.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 SOG2 PF10428.9 ORZ01660.1 - 0.026 13.8 15.7 0.034 13.4 15.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 ORZ01660.1 - 0.067 13.1 10.7 0.091 12.7 10.7 1.3 1 0 0 1 1 1 0 SPX domain Dicty_REP PF05086.12 ORZ01660.1 - 0.087 10.8 24.0 0.12 10.3 24.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF572 PF04502.13 ORZ01660.1 - 0.13 11.9 11.6 0.17 11.5 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SLC12 PF03522.15 ORZ01660.1 - 0.8 8.7 6.0 1 8.3 6.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CiPC PF15800.5 ORZ01660.1 - 1.5 8.5 26.9 2.7 7.6 26.9 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian GREB1 PF15782.5 ORZ01660.1 - 2.9 4.9 17.2 3.8 4.5 17.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 ORZ01660.1 - 3.5 5.6 10.9 4.3 5.3 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 ORZ01660.1 - 4.1 6.5 11.9 6 6.0 11.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4551 PF15087.6 ORZ01660.1 - 4.3 6.0 11.4 5.6 5.7 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Apt1 PF10351.9 ORZ01660.1 - 5.5 5.7 15.4 9.1 5.0 15.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S8 PF00082.22 ORZ01661.1 - 2.5e-44 151.7 3.0 4e-44 151.1 3.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORZ01661.1 - 3.4e-12 47.1 0.6 8.7e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 ORZ01661.1 - 0.00022 21.2 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF916 PF06030.12 ORZ01661.1 - 0.02 15.0 0.1 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF916) DUF1421 PF07223.11 ORZ01661.1 - 0.18 11.6 0.9 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain (DUF1421) PH_9 PF15410.6 ORZ01662.1 - 1.6e-30 105.9 0.0 4.5e-29 101.2 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 ORZ01662.1 - 2.6e-29 102.2 0.0 5.3e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 ORZ01662.1 - 0.00063 20.2 0.0 0.36 11.4 0.0 2.6 2 0 0 2 2 2 2 PH domain Lzipper-MIP1 PF14389.6 ORZ01662.1 - 0.14 12.4 1.2 0.39 11.0 1.2 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Nucleotid_trans PF03407.16 ORZ01663.1 - 5.2e-27 95.2 0.8 7.9e-27 94.6 0.8 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_hydro_28 PF00295.17 ORZ01670.1 - 2.8e-62 210.7 16.3 3.6e-62 210.3 16.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 ORZ01670.1 - 0.00052 19.9 17.4 0.008 16.0 17.4 2.3 1 1 1 2 2 2 1 Right handed beta helix region Glyco_hydro_28 PF00295.17 ORZ01671.1 - 4.6e-66 223.1 22.1 5.9e-66 222.7 22.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Guanylate_kin PF00625.21 ORZ01672.1 - 1.2e-63 214.1 0.0 1.4e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 ORZ01672.1 - 1.8e-06 28.2 0.0 2.5e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORZ01672.1 - 3.6e-05 24.3 0.0 6.2e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORZ01672.1 - 5.7e-05 23.4 0.0 9.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ01672.1 - 9.8e-05 22.8 0.1 0.00014 22.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ORZ01672.1 - 0.00042 20.8 0.0 0.00076 20.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 ORZ01672.1 - 0.00067 19.3 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORZ01672.1 - 0.0015 18.4 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ORZ01672.1 - 0.0018 18.8 0.3 0.0034 17.9 0.1 1.5 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 ORZ01672.1 - 0.0023 17.0 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 ORZ01672.1 - 0.0028 17.6 0.0 0.0029 17.6 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ORZ01672.1 - 0.0031 17.9 0.0 0.0079 16.6 0.0 1.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 ORZ01672.1 - 0.0033 17.7 0.1 0.0056 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 ORZ01672.1 - 0.0037 16.9 0.1 0.026 14.1 0.0 2.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORZ01672.1 - 0.005 16.9 0.0 0.0086 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 ORZ01672.1 - 0.01 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 ORZ01672.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORZ01672.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ORZ01672.1 - 0.02 14.6 0.0 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 ORZ01672.1 - 0.028 14.3 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2075 PF09848.9 ORZ01672.1 - 0.029 13.6 0.0 0.037 13.3 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 ORZ01672.1 - 0.033 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_24 PF13479.6 ORZ01672.1 - 0.037 13.7 0.1 0.041 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 ORZ01672.1 - 0.057 13.1 0.1 9.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 ORZ01672.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 NTPase NB-ARC PF00931.22 ORZ01672.1 - 0.071 12.3 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_21 PF13304.6 ORZ01672.1 - 0.095 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 ORZ01672.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.12 ORZ01672.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein BolA PF01722.18 ORZ01674.1 - 4e-23 81.5 2.5 4.4e-23 81.3 2.5 1.0 1 0 0 1 1 1 1 BolA-like protein DUF676 PF05057.14 ORZ01675.1 - 9.2e-22 77.6 0.1 1.9e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DDE_Tnp_IS1 PF03400.13 ORZ01675.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 IS1 transposase DUF676 PF05057.14 ORZ01676.1 - 3.3e-39 134.7 0.0 5.8e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ORZ01676.1 - 3.7e-05 23.7 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 ORZ01676.1 - 0.00048 19.9 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 ORZ01676.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF726 PF05277.12 ORZ01676.1 - 0.088 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 ORZ01676.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 ORZ01676.1 - 0.15 11.6 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family MOZART1 PF12554.8 ORZ01677.1 - 2.3e-24 84.9 1.1 2.6e-24 84.7 1.1 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated UCH_1 PF13423.6 ORZ01678.1 - 2.7e-99 332.8 0.6 3.4e-99 332.4 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 ORZ01678.1 - 2.2e-21 77.1 0.0 3.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 ORZ01678.1 - 2.2e-11 43.8 0.0 3.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_ligase_A_M PF01068.21 ORZ01678.1 - 0.0052 16.4 0.3 0.016 14.9 0.1 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain Cytochrome_C7 PF14522.6 ORZ01678.1 - 0.064 13.3 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Arrestin_N PF00339.29 ORZ01679.1 - 2.2e-11 44.0 0.0 2.8e-10 40.4 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORZ01679.1 - 1.6e-08 35.1 0.1 2e-05 25.0 0.2 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORZ01679.1 - 0.0042 16.8 0.0 0.051 13.3 0.0 2.5 2 1 1 3 3 3 1 Arrestin_N terminal like Vac_ImportDeg PF09783.9 ORZ01679.1 - 0.16 11.8 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 Vacuolar import and degradation protein ACC_central PF08326.12 ORZ01680.1 - 3e-252 839.1 0.3 3.9e-252 838.7 0.3 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORZ01680.1 - 1.2e-174 581.6 0.1 1.6e-174 581.2 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORZ01680.1 - 6.3e-54 182.7 0.1 2.2e-53 180.9 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORZ01680.1 - 4.3e-29 101.3 0.1 1.1e-28 99.9 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORZ01680.1 - 1.6e-22 79.7 0.0 9e-21 74.0 0.0 3.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORZ01680.1 - 1.9e-14 53.2 0.1 6e-14 51.6 0.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 ORZ01680.1 - 3.7e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORZ01680.1 - 0.0016 18.0 0.0 0.0048 16.5 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORZ01680.1 - 0.0023 17.5 0.0 0.0055 16.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORZ01680.1 - 0.033 14.0 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 ORZ01680.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 ORZ01680.1 - 0.14 11.8 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain RRM_9 PF18444.1 ORZ01682.1 - 1.1e-08 34.8 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif NTF2 PF02136.20 ORZ01682.1 - 6.7e-08 33.1 0.1 3.3e-07 30.9 0.1 2.1 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 ORZ01682.1 - 6.3e-05 22.6 0.0 9.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORZ01682.1 - 0.11 13.0 0.1 1.4 9.4 0.0 2.6 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) PBP1_TM PF14812.6 ORZ01682.1 - 0.28 11.6 5.7 6.8 7.1 1.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.29 ORZ01683.1 - 3.1e-09 36.6 7.0 5.8e-09 35.7 7.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORZ01683.1 - 0.00091 18.7 5.4 0.00091 18.7 5.4 2.3 2 1 0 2 2 2 1 PHD-finger C1_2 PF03107.16 ORZ01683.1 - 0.034 14.5 7.0 0.2 12.0 4.6 2.4 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 ORZ01683.1 - 0.048 13.6 3.7 0.09 12.7 3.7 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 ORZ01683.1 - 0.13 12.2 5.7 0.065 13.1 1.4 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pyridoxal_deC PF00282.19 ORZ01684.1 - 9.1e-69 232.0 0.0 1.8e-68 231.0 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORZ01684.1 - 5e-05 22.4 0.0 9.1e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 ORZ01685.1 - 4.1e-32 111.5 71.5 4.3e-27 95.0 40.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORZ01685.1 - 0.00073 18.2 10.2 0.00073 18.2 10.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein NUP50 PF08911.11 ORZ01686.1 - 0.0037 17.9 3.5 0.0037 17.9 3.5 5.1 4 4 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) TatD_DNase PF01026.21 ORZ01687.1 - 7.8e-53 179.4 0.1 9.1e-53 179.2 0.1 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 ORZ01687.1 - 0.0045 16.4 0.2 0.012 14.9 0.2 1.8 1 1 0 1 1 1 1 Amidohydrolase family NAD-GH PF10712.9 ORZ01687.1 - 0.045 12.2 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase AAA_28 PF13521.6 ORZ01687.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arm PF00514.23 ORZ01688.1 - 4.2e-31 106.0 19.0 1.5e-08 34.4 0.3 8.3 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORZ01688.1 - 1e-15 57.8 8.9 0.0015 18.9 0.1 5.9 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 ORZ01688.1 - 2.4e-15 55.3 19.2 0.0033 17.5 0.1 8.1 9 0 0 9 9 8 5 HEAT repeat HEAT_EZ PF13513.6 ORZ01688.1 - 2e-10 41.0 21.9 0.02 15.4 0.2 7.1 6 1 1 7 7 7 3 HEAT-like repeat Cnd1 PF12717.7 ORZ01688.1 - 1.3e-06 28.5 9.7 0.0013 18.8 0.9 3.6 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORZ01688.1 - 1.1e-05 25.9 0.6 0.43 11.2 0.0 4.3 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 ORZ01688.1 - 5.1e-05 23.3 6.9 0.15 12.0 0.0 4.1 3 1 2 5 5 5 2 Domain of unknown function (DUF3361) Adaptin_N PF01602.20 ORZ01688.1 - 0.00017 20.3 11.0 0.005 15.4 3.2 3.3 2 2 0 2 2 2 2 Adaptin N terminal region RTP1_C1 PF10363.9 ORZ01688.1 - 0.00048 20.3 2.4 0.76 10.0 0.0 3.9 2 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF5578 PF17741.1 ORZ01688.1 - 0.0016 17.9 5.0 2.1 7.7 0.1 3.3 3 0 0 3 3 3 2 Family of unknown function (DUF5578) DRIM PF07539.12 ORZ01688.1 - 0.0086 14.4 3.9 1.5 7.0 0.1 3.2 2 1 0 3 3 3 1 Down-regulated in metastasis RIX1 PF08167.12 ORZ01688.1 - 0.009 15.8 3.4 0.27 10.9 1.2 2.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.8 ORZ01688.1 - 0.011 15.9 1.5 3.7 7.7 0.0 3.7 2 1 2 4 4 4 0 V-ATPase subunit H DCB PF16213.5 ORZ01688.1 - 0.016 14.9 0.6 0.016 14.9 0.6 2.6 2 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 RasGEF_N_2 PF14663.6 ORZ01688.1 - 0.021 15.2 8.2 1.4 9.4 0.1 4.6 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3730 PF12530.8 ORZ01688.1 - 0.035 13.7 0.5 0.035 13.7 0.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3730) IFRD PF05004.13 ORZ01688.1 - 0.18 10.9 7.4 4.1 6.4 0.1 3.9 3 2 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 ORZ01688.1 - 0.56 9.7 2.7 45 3.4 0.0 3.7 3 2 1 4 4 4 0 Tti2 family Atx10homo_assoc PF09759.9 ORZ01688.1 - 3.1 7.9 7.0 9 6.4 0.0 4.2 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain PGAP1 PF07819.13 ORZ01689.1 - 6e-60 202.8 0.0 9.2e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORZ01689.1 - 3.8e-05 24.4 7.0 0.0002 22.0 6.8 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORZ01689.1 - 0.00066 19.0 0.1 0.0016 17.8 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 ORZ01689.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ORZ01689.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 ORZ01689.1 - 0.0037 16.9 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 ORZ01689.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 ORZ01689.1 - 0.18 11.1 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_S3Ae PF01015.18 ORZ01690.1 - 1e-89 299.5 4.5 1.2e-89 299.2 4.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Minor_capsid_2 PF11114.8 ORZ01690.1 - 0.13 12.3 0.1 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Minor capsid protein TipAS PF07739.13 ORZ01690.1 - 0.14 12.7 0.1 1.3 9.6 0.0 2.4 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Bot1p PF12298.8 ORZ01692.1 - 1.3e-12 48.3 8.4 7e-11 42.6 0.1 2.9 2 1 1 3 3 3 2 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 ORZ01692.1 - 0.00073 19.7 1.4 0.0018 18.5 1.2 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Ribosomal_L30 PF00327.20 ORZ01693.1 - 9.6e-13 47.8 0.0 1.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PPR_2 PF13041.6 ORZ01694.1 - 1.7e-56 188.2 11.4 2.1e-10 40.7 0.0 12.7 9 3 6 15 15 14 12 PPR repeat family PPR_3 PF13812.6 ORZ01694.1 - 1.6e-41 140.2 7.7 1.4e-08 34.7 0.0 10.8 8 2 3 11 11 11 8 Pentatricopeptide repeat domain PPR PF01535.20 ORZ01694.1 - 4.2e-38 126.9 7.0 0.00034 20.6 0.0 13.6 15 0 0 15 15 14 8 PPR repeat PPR_1 PF12854.7 ORZ01694.1 - 8.4e-28 95.8 6.5 1.1e-05 25.0 0.0 12.3 14 0 0 14 14 13 5 PPR repeat PPR_long PF17177.4 ORZ01694.1 - 4.8e-24 84.9 0.8 2.3e-08 33.6 0.0 5.4 2 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 ORZ01694.1 - 5.5e-05 22.2 0.2 0.17 10.7 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial 28S ribosomal protein S27 TPR_MalT PF17874.1 ORZ01694.1 - 0.0032 16.9 0.4 0.01 15.2 0.0 1.9 2 0 0 2 2 2 1 MalT-like TPR region ECSIT PF06239.11 ORZ01694.1 - 0.0074 15.4 1.1 1.3 8.1 0.0 3.8 4 1 1 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.6 ORZ01694.1 - 0.011 16.5 10.2 13 6.9 0.0 6.7 4 2 3 7 7 7 0 Tetratricopeptide repeat RPM2 PF08579.11 ORZ01694.1 - 0.027 14.9 0.9 20 5.6 0.0 4.3 4 1 1 5 5 4 0 Mitochondrial ribonuclease P subunit (RPM2) Wzy_C_2 PF11846.8 ORZ01694.1 - 0.03 14.3 2.6 8.6 6.2 0.0 3.3 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal MNE1 PF13762.6 ORZ01694.1 - 0.043 13.8 0.2 6.9 6.6 0.0 3.8 3 2 0 3 3 3 0 Mitochondrial splicing apparatus component ATPgrasp_N PF18130.1 ORZ01694.1 - 0.078 13.5 0.3 1.4 9.5 0.0 3.0 2 0 0 2 2 2 0 ATP-grasp N-terminal domain TPR_4 PF07721.14 ORZ01694.1 - 0.29 11.9 3.8 29 5.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Tir_receptor_C PF07489.11 ORZ01694.1 - 0.37 10.7 2.5 0.69 9.9 2.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus BTAD PF03704.17 ORZ01694.1 - 1.2 9.6 8.4 7.8 6.9 1.4 4.3 4 1 1 5 5 5 0 Bacterial transcriptional activator domain Septin PF00735.18 ORZ01695.1 - 1.1e-112 375.9 0.2 1.8e-112 375.2 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORZ01695.1 - 4.1e-08 33.3 0.1 1e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORZ01695.1 - 0.002 17.7 0.0 0.0093 15.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORZ01695.1 - 0.002 17.5 0.0 0.0067 15.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family tRNA_synthFbeta PF17759.1 ORZ01695.1 - 0.014 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain RsgA_GTPase PF03193.16 ORZ01695.1 - 0.017 15.0 0.3 0.017 15.0 0.3 2.2 3 1 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 ORZ01695.1 - 0.025 15.1 0.0 0.44 11.1 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 ORZ01695.1 - 0.056 13.5 5.2 2.8 8.0 0.0 3.1 2 1 1 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 ORZ01695.1 - 0.075 12.4 0.2 0.17 11.2 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family EB1 PF03271.17 ORZ01695.1 - 0.19 12.0 1.3 0.83 9.9 1.3 2.1 1 0 0 1 1 1 0 EB1-like C-terminal motif AAA_23 PF13476.6 ORZ01695.1 - 0.69 10.4 8.4 20 5.6 7.5 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORZ01695.1 - 0.72 10.1 2.6 0.94 9.8 0.1 2.5 2 2 0 2 2 2 0 AAA domain DUF4140 PF13600.6 ORZ01695.1 - 1.8 9.0 6.7 67 4.0 5.0 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) F-box-like PF12937.7 ORZ01696.1 - 9.6e-07 28.6 0.4 6.9e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORZ01696.1 - 1.1e-06 28.4 0.1 1.1e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 F-box domain Acetyltransf_1 PF00583.25 ORZ01697.1 - 2.5e-15 56.7 0.0 3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORZ01697.1 - 4.4e-12 46.0 0.0 5.5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORZ01697.1 - 4.9e-12 46.1 0.0 6.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORZ01697.1 - 0.00015 21.9 0.0 0.00028 21.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORZ01697.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 ORZ01697.1 - 0.0002 21.1 0.1 0.00026 20.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 ORZ01697.1 - 0.00085 19.5 0.0 0.0014 18.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORZ01697.1 - 0.0009 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 ORZ01697.1 - 0.0089 15.5 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 ORZ01697.1 - 0.032 14.2 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase GNAT_acetyltran PF12746.7 ORZ01697.1 - 0.096 12.2 0.0 0.28 10.7 0.0 1.7 1 1 1 2 2 2 0 GNAT acetyltransferase Acetyltransf_3 PF13302.7 ORZ01697.1 - 0.14 12.8 0.0 0.16 12.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PGM_PMM_I PF02878.16 ORZ01698.1 - 8.6e-34 116.2 0.0 1.5e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ORZ01698.1 - 7.2e-29 100.3 0.0 1.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORZ01698.1 - 9.2e-14 51.9 0.1 2.4e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORZ01698.1 - 3.6e-08 33.5 0.0 8.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.25 ORZ01699.1 - 5.2e-74 248.9 0.0 6.6e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ01699.1 - 9.1e-45 153.0 0.0 1.1e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ01699.1 - 2.8e-11 43.3 0.0 4.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORZ01699.1 - 0.00018 21.0 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORZ01699.1 - 0.0046 16.6 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORZ01699.1 - 0.0081 15.0 0.1 0.013 14.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORZ01699.1 - 0.0094 15.0 0.1 0.019 14.0 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Haspin_kinase PF12330.8 ORZ01699.1 - 0.028 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORZ01699.1 - 0.039 13.9 0.1 0.088 12.7 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CAP PF00188.26 ORZ01700.1 - 7.9e-25 88.1 10.6 3.8e-24 85.9 10.6 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Nodulin_late PF07127.11 ORZ01701.1 - 2.5e-05 24.5 0.4 3e-05 24.3 0.4 1.1 1 0 0 1 1 1 1 Late nodulin protein Claudin_2 PF13903.6 ORZ01702.1 - 0.029 14.1 7.7 0.058 13.2 7.7 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction 5TM-5TMR_LYT PF07694.12 ORZ01702.1 - 0.14 11.7 3.7 0.23 10.9 3.7 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT ArAE_1 PF06081.11 ORZ01702.1 - 0.23 11.6 6.4 0.41 10.8 6.4 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 DUF5360 PF17314.2 ORZ01702.1 - 2.3 8.3 4.4 1.2 9.2 0.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5360) tRNA-synt_1d PF00750.19 ORZ01703.1 - 8.1e-80 268.4 0.2 1.5e-79 267.5 0.2 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORZ01703.1 - 2.6e-22 79.2 0.0 5.1e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Trehalase PF01204.18 ORZ01704.1 - 5.4e-180 599.6 1.9 6.9e-180 599.2 1.9 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 ORZ01704.1 - 8.6e-14 51.0 0.1 1.6e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain MFS_1 PF07690.16 ORZ01705.1 - 9.9e-40 136.5 21.4 9.9e-40 136.5 21.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.15 ORZ01705.1 - 0.003 17.8 0.4 0.0091 16.2 0.4 1.8 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EOS1 PF12326.8 ORZ01705.1 - 0.0037 17.2 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 N-glycosylation protein DUF973 PF06157.11 ORZ01705.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) FAM176 PF14851.6 ORZ01705.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 ORZ01705.1 - 0.16 12.2 3.1 0.31 11.3 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Rad51 PF08423.11 ORZ01707.1 - 8.9e-22 77.6 0.0 1.3e-21 77.1 0.0 1.2 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.15 ORZ01707.1 - 1.6e-07 30.9 0.1 2.1e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 ORZ01707.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2107 PF09880.9 ORZ01707.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) PLDc PF00614.22 ORZ01708.1 - 2e-17 62.5 1.3 6.9e-10 38.7 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORZ01708.1 - 3.4e-16 59.3 0.3 1.3e-06 28.4 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain BLM10_mid PF16507.5 ORZ01709.1 - 1.8e-162 541.7 0.1 1.2e-161 539.0 0.0 2.1 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 ORZ01709.1 - 6.7e-34 115.7 0.0 5.4e-32 109.6 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 ORZ01709.1 - 0.015 15.5 0.0 0.88 10.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat LIDHydrolase PF10230.9 ORZ01709.1 - 0.071 12.7 0.5 0.21 11.1 0.5 1.8 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Phytochelatin PF05023.14 ORZ01710.1 - 1.8e-87 292.1 0.0 2.5e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 ORZ01710.1 - 0.004 17.7 0.0 0.015 15.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase_C39 like family Peroxin-13_N PF04088.13 ORZ01711.1 - 5.7e-47 159.6 1.0 1.2e-46 158.6 1.0 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 ORZ01711.1 - 3.1e-13 49.1 0.0 5.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORZ01711.1 - 1.2e-11 44.1 0.0 2.5e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORZ01711.1 - 8.9e-11 41.5 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 ORZ01711.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region SUIM_assoc PF16619.5 ORZ01711.1 - 0.66 10.1 7.7 0.18 11.9 2.9 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Motile_Sperm PF00635.26 ORZ01712.1 - 0.00065 19.5 0.0 0.0082 16.0 0.0 2.0 2 0 0 2 2 2 1 MSP (Major sperm protein) domain START PF01852.19 ORZ01715.1 - 2.7e-24 85.7 0.3 1.3e-12 47.6 0.0 3.0 3 0 0 3 3 3 2 START domain Glyco_hydro_5_C PF18564.1 ORZ01715.1 - 0.001 19.6 0.1 0.0029 18.1 0.1 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain NOA36 PF06524.12 ORZ01715.1 - 0.18 11.1 4.3 0.33 10.2 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein Acetyltransf_CG PF14542.6 ORZ01716.1 - 2.8e-15 56.2 0.0 4.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Dicty_REP PF05086.12 ORZ01716.1 - 1.2 7.0 4.4 1.6 6.7 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.13 ORZ01716.1 - 1.4 9.6 11.2 0.6 10.8 2.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.17 ORZ01716.1 - 2.5 8.1 22.3 5.5 7.0 22.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SNF2_N PF00176.23 ORZ01717.1 - 8.7e-51 172.7 1.5 5.3e-50 170.1 1.4 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORZ01717.1 - 1.1e-13 51.5 0.0 3.3e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ01717.1 - 1.1e-07 32.0 0.0 3.6e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORZ01717.1 - 7.9e-05 22.5 0.6 0.00024 20.9 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 ORZ01717.1 - 0.0019 17.5 0.1 0.0035 16.6 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AbiJ_NTD4 PF18863.1 ORZ01717.1 - 0.0054 17.2 0.8 0.013 16.0 0.8 1.6 1 0 0 1 1 1 1 AbiJ N-terminal domain 4 DNA_ligase_A_N PF04675.14 ORZ01717.1 - 0.045 14.1 0.1 0.091 13.1 0.1 1.5 1 1 0 1 1 1 0 DNA ligase N terminus Exo_endo_phos PF03372.23 ORZ01717.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 ORZ01719.1 - 0.00043 20.0 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.12 ORZ01720.1 - 4.6e-38 131.3 0.0 1.4e-37 129.7 0.0 1.8 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Rpp20 PF12328.8 ORZ01721.1 - 0.018 15.0 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P OTT_1508_deam PF14441.6 ORZ01721.1 - 0.058 13.4 0.1 0.099 12.7 0.1 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase Helicase_C PF00271.31 ORZ01722.1 - 5.3e-20 71.8 0.0 1.7e-16 60.5 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 ORZ01722.1 - 2.9e-18 65.7 0.1 6.1e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 ORZ01722.1 - 3.2e-18 66.1 0.0 7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 ORZ01722.1 - 1.3e-14 54.6 2.8 1.3e-14 54.6 2.8 2.3 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 ORZ01722.1 - 0.002 18.2 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit LURAP PF14854.6 ORZ01722.1 - 0.024 14.6 0.1 0.068 13.1 0.1 1.7 1 0 0 1 1 1 0 Leucine rich adaptor protein SecA_DEAD PF07517.14 ORZ01722.1 - 0.065 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain HisK_sensor PF18698.1 ORZ01722.1 - 0.088 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase sensor domain DUF572 PF04502.13 ORZ01726.1 - 2.5e-75 254.2 1.4 3.1e-75 253.9 1.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) AFG1_ATPase PF03969.16 ORZ01727.1 - 1.5e-115 386.0 0.6 6.1e-110 367.5 0.1 2.0 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 ORZ01727.1 - 1.9e-05 25.1 0.1 0.02 15.3 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ORZ01727.1 - 0.00016 22.0 0.0 0.0006 20.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 ORZ01727.1 - 0.043 13.5 0.0 0.99 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 ORZ01727.1 - 0.051 13.9 0.0 7.1 6.9 0.0 2.6 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 ORZ01727.1 - 0.075 12.9 0.3 0.71 9.7 0.1 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein WhiA_N PF10298.9 ORZ01727.1 - 0.11 12.6 0.1 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain TsaE PF02367.17 ORZ01727.1 - 0.13 12.3 0.0 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 ORZ01727.1 - 0.13 11.7 0.0 0.65 9.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Mrx7 PF10906.8 ORZ01727.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 MIOREX complex component 7 ATPase_2 PF01637.18 ORZ01727.1 - 0.19 11.6 0.0 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea eIF-1a PF01176.19 ORZ01728.1 - 4.8e-21 74.3 0.0 6.5e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NDT80_PhoG PF05224.12 ORZ01729.1 - 1.7e-28 100.1 4.7 4e-23 82.6 0.1 3.3 1 1 1 2 2 2 2 NDT80 / PhoG like DNA-binding family Cir_N PF10197.9 ORZ01730.1 - 8.4e-10 38.7 9.8 8.4e-10 38.7 9.8 4.5 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Tubulin_3 PF14881.6 ORZ01731.1 - 2.7e-47 160.8 0.2 4.8e-47 160.0 0.2 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 ORZ01731.1 - 1.7e-39 134.7 1.1 1.7e-39 134.7 1.1 2.0 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 ORZ01731.1 - 1e-10 42.1 0.0 3.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PDCD7 PF16021.5 ORZ01732.1 - 2e-15 56.7 32.4 3.3e-09 36.3 2.9 2.1 2 0 0 2 2 2 2 Programmed cell death protein 7 VPS38 PF17649.1 ORZ01732.1 - 0.95 8.3 2.8 1 8.1 2.8 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 FUSC PF04632.12 ORZ01732.1 - 2.8 6.4 9.8 3.4 6.1 9.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ytp1 PF10355.9 ORZ01733.1 - 2.2e-56 191.1 19.4 2e-54 184.7 19.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORZ01733.1 - 1.7e-13 50.2 2.1 1.7e-13 50.2 2.1 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 ORZ01733.1 - 1.2e-05 25.5 5.9 1.2e-05 25.5 5.9 3.5 3 1 0 4 4 4 1 Eukaryotic cytochrome b561 SWIRM-assoc_1 PF16495.5 ORZ01735.1 - 0.52 10.3 2.2 2.6 8.1 0.0 2.5 3 0 0 3 3 3 0 SWIRM-associated region 1 VASt PF16016.5 ORZ01736.1 - 7.5e-37 127.1 0.0 1.4e-36 126.3 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ORZ01736.1 - 3.5e-25 88.1 0.0 7.2e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF5616 PF18481.1 ORZ01736.1 - 0.092 13.1 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) Cyclin_N PF00134.23 ORZ01737.1 - 3.3e-14 52.7 1.2 8.3e-14 51.4 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 ORZ01737.1 - 4e-07 30.4 0.7 1.8e-06 28.3 0.1 2.4 2 1 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.19 ORZ01737.1 - 0.00086 19.3 0.5 0.002 18.1 0.0 1.9 2 1 0 2 2 2 1 Transcription factor TFIIB repeat RB_B PF01857.20 ORZ01737.1 - 0.033 14.2 1.8 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 ORZ01737.1 - 0.048 13.8 0.8 3 7.9 0.0 2.5 2 1 0 2 2 2 0 Cyclin, C-terminal domain TAL_FSA PF00923.19 ORZ01738.1 - 2.8e-97 325.5 0.0 3.2e-97 325.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pep3_Vps18 PF05131.14 ORZ01739.1 - 1e-53 181.2 0.3 3.2e-53 179.5 0.1 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 ORZ01739.1 - 4.7e-12 46.0 17.7 3.9e-09 36.5 3.1 3.7 4 1 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 ORZ01739.1 - 0.055 13.9 0.0 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Syntaxin-6_N PF09177.11 ORZ01739.1 - 0.14 12.7 0.2 0.69 10.5 0.2 2.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TPR_1 PF00515.28 ORZ01739.1 - 1.4 8.9 9.7 33 4.5 1.9 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ01739.1 - 1.4 9.3 3.9 30 5.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.23 ORZ01740.1 - 4.9e-95 318.3 0.0 5.9e-95 318.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORZ01740.1 - 1.4e-15 57.6 0.0 2.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding zf-ANAPC11 PF12861.7 ORZ01741.1 - 1.2e-35 121.5 11.0 1.3e-35 121.3 11.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORZ01741.1 - 2.5e-20 72.5 12.1 3.1e-20 72.2 12.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORZ01741.1 - 1e-06 28.9 14.9 1.4e-05 25.3 14.9 2.1 1 1 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 ORZ01741.1 - 0.011 15.4 6.6 0.011 15.4 6.6 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ORZ01741.1 - 0.058 13.4 11.6 0.44 10.5 12.0 2.3 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 ORZ01741.1 - 0.096 12.9 9.7 0.18 12.0 9.7 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 ORZ01741.1 - 0.097 12.5 16.5 4.2 7.3 16.5 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ01741.1 - 0.25 11.2 14.4 1.6 8.7 14.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORZ01741.1 - 0.4 10.7 12.6 0.69 10.0 12.6 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 ORZ01741.1 - 1.5 8.6 13.6 21 5.0 13.6 2.5 1 1 0 1 1 1 0 RING-like zinc finger PDCD2_C PF04194.13 ORZ01742.1 - 2.6e-38 131.8 3.1 7.8e-37 127.0 0.0 2.8 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 ORZ01742.1 - 1.1e-07 31.8 11.9 1.1e-07 31.8 11.9 3.1 3 1 0 3 3 3 1 MYND finger PAS_11 PF14598.6 ORZ01744.1 - 0.078 13.1 0.1 0.26 11.4 0.1 1.9 1 0 0 1 1 1 0 PAS domain HTH_ABP1_N PF18107.1 ORZ01745.1 - 2.6e-06 27.0 1.2 3.9e-06 26.5 1.1 1.4 1 1 0 1 1 1 1 Fission yeast centromere protein N-terminal domain IPK PF03770.16 ORZ01747.1 - 5.7e-46 156.9 0.1 3.7e-44 151.0 0.1 2.1 1 1 0 1 1 1 1 Inositol polyphosphate kinase RNA_pol_3_Rpc31 PF11705.8 ORZ01747.1 - 0.0019 18.5 0.3 0.0035 17.6 0.3 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Phosphodiest PF01663.22 ORZ01748.1 - 7.9e-77 259.2 2.2 9e-77 259.1 2.2 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 ORZ01748.1 - 0.00026 20.5 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORZ01748.1 - 0.00035 20.1 0.3 0.001 18.5 0.3 2.1 1 1 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 ORZ01748.1 - 0.01 15.0 0.3 0.019 14.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) PglZ PF08665.12 ORZ01748.1 - 0.047 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 PglZ domain Phosphodiest PF01663.22 ORZ01749.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase XPC-binding PF09280.11 ORZ01750.1 - 0.032 14.0 1.2 0.25 11.1 0.0 2.6 2 1 0 2 2 2 0 XPC-binding domain Surp PF01805.20 ORZ01751.1 - 4.8e-18 64.9 0.3 9.3e-18 64.0 0.3 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 ORZ01751.1 - 6e-16 58.0 0.0 1.6e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.8 ORZ01751.1 - 4.2e-05 23.5 0.0 9.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 TFIIA PF03153.13 ORZ01751.1 - 0.0017 18.5 8.5 0.0017 18.5 8.5 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RRM_7 PF16367.5 ORZ01751.1 - 0.003 17.6 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 ORZ01751.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 ORZ01751.1 - 0.065 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S8e PF01201.22 ORZ01752.1 - 5e-51 172.5 4.4 1.2e-50 171.3 4.4 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e M20_dimer PF07687.14 ORZ01753.1 - 3.6e-13 49.4 0.0 7.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORZ01753.1 - 4.3e-06 26.6 0.1 6.8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORZ01754.1 - 4.6e-10 39.4 0.0 1.2e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORZ01754.1 - 2.7e-07 30.5 0.3 5e-07 29.6 0.2 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Iso_dh PF00180.20 ORZ01755.1 - 1e-81 274.8 0.1 1.2e-81 274.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tRNA_U5-meth_tr PF05958.11 ORZ01756.1 - 4.9e-13 48.8 0.0 4.2e-12 45.7 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 ORZ01756.1 - 7.2e-11 42.1 0.1 1.9e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ01756.1 - 3.2e-08 34.2 0.2 1.6e-07 32.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ01756.1 - 2.5e-06 27.2 0.1 6.6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 ORZ01756.1 - 1.2e-05 25.0 0.1 2.7e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 ORZ01756.1 - 2.9e-05 23.5 0.1 9.1e-05 21.9 0.1 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 ORZ01756.1 - 0.00019 20.9 0.1 0.00054 19.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 ORZ01756.1 - 0.00019 21.1 0.0 0.00054 19.6 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 ORZ01756.1 - 0.00023 21.0 0.0 0.0008 19.2 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 ORZ01756.1 - 0.00025 21.6 0.1 0.0021 18.7 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain AviRa PF11599.8 ORZ01756.1 - 0.0013 18.2 0.0 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_23 PF13489.6 ORZ01756.1 - 0.0035 17.2 0.1 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORZ01756.1 - 0.011 15.8 0.0 0.036 14.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 ORZ01756.1 - 0.02 14.5 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 Nodulation protein S (NodS) Met_10 PF02475.16 ORZ01756.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 ORZ01756.1 - 0.054 13.0 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 ORZ01756.1 - 0.056 14.2 0.0 0.19 12.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 ORZ01756.1 - 0.12 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Sugar_tr PF00083.24 ORZ01757.1 - 2.8e-92 310.0 28.1 3.3e-92 309.7 28.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ01757.1 - 1.7e-26 93.0 35.5 5.5e-18 65.0 8.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORZ01757.1 - 0.00015 20.4 4.5 0.00015 20.4 4.5 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) INCENP_ARK-bind PF03941.15 ORZ01758.1 - 2.9e-11 43.1 1.9 5.1e-11 42.4 0.4 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region ARL6IP6 PF15062.6 ORZ01759.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Big_7 PF17957.1 ORZ01760.1 - 0.00069 20.3 5.4 0.019 15.7 0.1 2.5 2 0 0 2 2 2 2 Bacterial Ig domain PA26 PF04636.13 ORZ01761.1 - 2.9e-97 326.4 0.0 4.7e-97 325.7 0.0 1.3 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) PX PF00787.24 ORZ01762.1 - 5.2e-26 90.8 0.0 6.5e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 PX domain HAUS4 PF14735.6 ORZ01763.1 - 1.7e-19 70.5 10.3 3.4e-19 69.5 10.3 1.5 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 PA28_beta PF02252.18 ORZ01764.1 - 0.073 12.7 0.1 0.94 9.1 0.0 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit NuA4 PF09340.10 ORZ01764.1 - 0.085 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 TFIIA PF03153.13 ORZ01765.1 - 0.0026 17.8 15.1 0.0036 17.4 15.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NPR1_interact PF15699.5 ORZ01765.1 - 1.3 9.7 7.7 0.75 10.5 4.1 2.0 2 0 0 2 2 2 0 NPR1 interacting RAP1 PF07218.11 ORZ01765.1 - 4.3 5.5 4.4 5.7 5.1 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) C2 PF00168.30 ORZ01767.1 - 2.1e-22 79.4 2.3 3.8e-11 43.2 0.2 3.1 3 0 0 3 3 3 2 C2 domain CCDC53 PF10152.9 ORZ01767.1 - 0.0039 17.6 0.8 0.0039 17.6 0.8 3.1 3 0 0 3 3 3 1 Subunit CCDC53 of WASH complex N_BRCA1_IG PF16158.5 ORZ01768.1 - 2.4e-27 95.6 0.0 1e-26 93.6 0.0 2.2 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 ORZ01768.1 - 1.4e-12 47.2 22.3 1e-08 34.8 8.5 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type FdhE PF04216.12 ORZ01768.1 - 8.6e-05 22.6 0.8 8.6e-05 22.6 0.8 2.0 2 0 0 2 2 2 1 Protein involved in formate dehydrogenase formation UBA_4 PF14555.6 ORZ01768.1 - 0.035 13.9 0.1 0.098 12.5 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain TrkH PF02386.16 ORZ01769.1 - 4.4e-78 262.9 13.9 8.1e-78 262.1 5.6 2.1 2 0 0 2 2 2 2 Cation transport protein TrkH PF02386.16 ORZ01770.1 - 4.4e-09 35.3 0.0 1.3e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Cation transport protein TrkH PF02386.16 ORZ01771.1 - 5.7e-50 170.2 8.9 8.2e-50 169.7 8.9 1.2 1 0 0 1 1 1 1 Cation transport protein DUF2244 PF10003.9 ORZ01771.1 - 7.7 6.2 10.8 7.8 6.2 1.8 2.7 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) G_glu_transpept PF01019.21 ORZ01772.1 - 9.6e-147 489.8 0.0 1.1e-146 489.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase E2F_TDP PF02319.20 ORZ01773.1 - 1.1e-24 86.2 1.2 1.9e-24 85.5 0.1 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 ORZ01773.1 - 1.5e-07 31.7 0.5 2.6e-07 30.9 0.5 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain TrmB PF01978.19 ORZ01773.1 - 0.029 14.2 0.1 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB UPF0122 PF04297.14 ORZ01773.1 - 0.046 14.0 0.3 0.83 9.9 0.0 2.2 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Exonuc_VII_L PF02601.15 ORZ01773.1 - 0.056 13.0 0.3 0.066 12.8 0.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mst1_SARAH PF11629.8 ORZ01773.1 - 0.08 13.0 1.9 0.17 12.0 1.8 1.7 1 1 0 1 1 1 0 C terminal SARAH domain of Mst1 SR-25 PF10500.9 ORZ01773.1 - 0.52 9.9 7.6 0.047 13.3 1.8 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RCC1 PF00415.18 ORZ01774.1 - 2.4e-40 136.9 12.3 3.1e-08 34.1 0.1 6.7 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORZ01774.1 - 3.2e-22 77.8 25.0 2e-07 30.6 0.0 5.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat zf-C2H2 PF00096.26 ORZ01776.1 - 5.7e-11 42.2 13.1 2e-05 24.8 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ01776.1 - 1.1e-09 38.3 19.5 5.4e-06 26.6 3.8 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ01776.1 - 6.2e-06 26.6 11.3 0.012 16.4 1.2 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ01776.1 - 0.0077 16.8 0.8 0.022 15.3 0.1 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain Zn-C2H2_12 PF18112.1 ORZ01776.1 - 0.016 15.6 0.7 2.8 8.5 0.2 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_8 PF15909.5 ORZ01776.1 - 0.033 14.5 2.2 0.059 13.7 1.8 1.7 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORZ01776.1 - 0.046 14.0 1.3 1.1 9.6 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORZ01776.1 - 0.27 11.0 11.8 0.48 10.2 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 ORZ01776.1 - 0.48 10.8 3.5 0.95 9.8 3.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Dicty_REP PF05086.12 ORZ01776.1 - 0.86 7.5 2.8 0.96 7.3 2.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNase_PH PF01138.21 ORZ01777.1 - 1.3e-22 80.7 0.0 1.8e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORZ01777.1 - 9.4e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CLASP_N PF12348.8 ORZ01778.1 - 2e-54 184.6 5.2 2e-54 184.6 5.2 1.8 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 ORZ01778.1 - 0.00021 21.3 0.4 0.63 10.5 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat RTP1_C1 PF10363.9 ORZ01778.1 - 0.0017 18.5 2.3 35 4.6 0.0 5.0 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Casc1_N PF15927.5 ORZ01778.1 - 0.08 12.6 0.5 0.2 11.4 0.5 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus CHASE8 PF17152.4 ORZ01778.1 - 0.099 12.9 0.3 0.81 10.0 0.0 2.6 2 0 0 2 2 2 0 Periplasmic sensor domain Adaptin_N PF01602.20 ORZ01778.1 - 0.14 10.7 2.4 0.33 9.5 0.5 2.6 3 0 0 3 3 3 0 Adaptin N terminal region MMS19_N PF14500.6 ORZ01778.1 - 0.44 10.1 2.4 3.6 7.1 1.1 3.0 2 2 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Apolipoprotein PF01442.18 ORZ01778.1 - 1.6 8.6 8.8 0.19 11.6 3.6 2.1 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain ABC_tran PF00005.27 ORZ01779.1 - 7.2e-48 162.6 0.0 4.2e-24 85.6 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORZ01779.1 - 4.7e-15 55.6 0.1 7.3e-06 25.6 0.0 4.4 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORZ01779.1 - 1.1e-13 51.7 1.3 0.00033 20.5 0.4 4.4 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORZ01779.1 - 5.4e-09 36.2 0.1 0.00066 19.6 0.1 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 ORZ01779.1 - 9.4e-09 35.7 0.0 0.032 14.5 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 ORZ01779.1 - 1.7e-07 31.7 0.1 0.089 13.2 0.0 4.7 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ORZ01779.1 - 3e-07 30.5 0.0 0.01 15.9 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORZ01779.1 - 4.9e-07 29.4 0.0 0.023 14.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MeaB PF03308.16 ORZ01779.1 - 5.3e-07 28.9 0.1 0.0029 16.6 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ORZ01779.1 - 1.1e-06 29.1 1.7 0.026 14.9 0.0 3.9 3 1 0 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 ORZ01779.1 - 3.5e-06 27.3 0.0 0.053 13.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORZ01779.1 - 5.7e-06 26.9 0.0 0.031 14.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORZ01779.1 - 1.1e-05 25.3 0.0 0.83 9.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 ORZ01779.1 - 1.6e-05 24.8 0.0 0.15 12.0 0.0 3.3 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 ORZ01779.1 - 2.9e-05 24.4 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 ORZ01779.1 - 5.1e-05 23.5 0.0 0.56 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 ORZ01779.1 - 7.9e-05 21.9 0.0 0.096 11.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 ORZ01779.1 - 8.8e-05 22.4 3.3 0.13 12.0 0.0 3.1 4 0 0 4 4 3 2 AAA ATPase domain AAA_23 PF13476.6 ORZ01779.1 - 0.00013 22.6 13.3 0.01 16.3 0.0 3.6 2 1 0 2 2 2 1 AAA domain Chromo PF00385.24 ORZ01779.1 - 0.00033 20.5 0.2 0.00033 20.5 0.2 2.4 3 0 0 3 3 1 1 Chromo (CHRromatin Organisation MOdifier) domain PduV-EutP PF10662.9 ORZ01779.1 - 0.00036 20.3 0.0 0.29 10.9 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 ORZ01779.1 - 0.0011 19.0 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_14 PF13173.6 ORZ01779.1 - 0.0011 19.0 0.0 2.6 8.1 0.0 3.4 2 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 ORZ01779.1 - 0.0024 18.1 0.0 0.41 10.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CLP1_P PF16575.5 ORZ01779.1 - 0.0027 17.5 0.0 0.36 10.6 0.0 2.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 ORZ01779.1 - 0.003 17.7 1.2 0.78 9.8 0.0 3.2 3 0 0 3 3 2 1 Helicase HerA, central domain NB-ARC PF00931.22 ORZ01779.1 - 0.0062 15.7 0.0 0.67 9.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 ORZ01779.1 - 0.011 15.8 0.0 1.2 9.2 0.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 ORZ01779.1 - 0.011 15.2 0.0 2.9 7.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_27 PF13514.6 ORZ01779.1 - 0.012 15.2 0.0 6.3 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORZ01779.1 - 0.014 15.1 0.0 0.83 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORZ01779.1 - 0.015 15.0 0.0 9.3 5.9 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 ORZ01779.1 - 0.02 14.8 0.1 2.9 7.8 0.1 2.9 2 0 0 2 2 2 0 NTPase PRK PF00485.18 ORZ01779.1 - 0.021 14.5 0.1 1.3 8.7 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 ORZ01779.1 - 0.026 14.5 0.0 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ORZ01779.1 - 0.036 13.4 0.6 7.4 5.8 0.4 2.9 2 1 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 ORZ01779.1 - 0.04 12.6 5.1 6.4 5.3 0.0 4.1 5 0 0 5 5 5 0 AAA domain ATP-synt_ab PF00006.25 ORZ01779.1 - 0.063 12.9 0.0 0.52 9.9 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 ORZ01779.1 - 0.065 13.5 0.0 23 5.2 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase 4HB PF17947.1 ORZ01779.1 - 0.066 13.3 0.1 0.066 13.3 0.1 2.7 3 0 0 3 3 1 0 Four helical bundle domain Viral_helicase1 PF01443.18 ORZ01779.1 - 0.073 12.8 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FeoB_N PF02421.18 ORZ01779.1 - 0.082 12.4 0.0 7.6 6.0 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 ORZ01779.1 - 0.12 11.5 0.0 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 ORZ01779.1 - 0.13 12.3 0.0 29 4.6 0.0 3.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 ORZ01779.1 - 0.14 11.7 0.1 24 4.4 0.0 3.0 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 ORZ01779.1 - 0.19 11.6 7.0 1.9 8.4 0.0 3.5 4 1 0 4 4 2 0 ATPase domain predominantly from Archaea STAG PF08514.11 ORZ01780.1 - 1.1 9.3 6.6 0.79 9.7 1.2 2.1 1 1 1 2 2 2 0 STAG domain SET PF00856.28 ORZ01781.1 - 1.6e-09 38.3 0.0 6.9e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 SET domain Methyltransf_11 PF08241.12 ORZ01782.1 - 2.3e-13 50.6 0.0 4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ01782.1 - 3.7e-13 50.0 0.0 8.2e-13 48.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ01782.1 - 7.7e-12 45.2 0.1 9.6e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ01782.1 - 1.1e-10 41.6 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ01782.1 - 7.9e-10 39.4 0.0 1.3e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ01782.1 - 0.00025 20.6 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 ORZ01782.1 - 0.0026 17.9 0.0 0.0044 17.1 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 ORZ01782.1 - 0.009 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 ORZ01782.1 - 0.039 13.9 0.1 0.16 12.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 ORZ01782.1 - 0.06 13.0 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) CheR PF01739.18 ORZ01782.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 ORZ01782.1 - 0.072 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Pox_MCEL PF03291.16 ORZ01782.1 - 0.091 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme CMAS PF02353.20 ORZ01782.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 ORZ01782.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Baculo_LEF-11 PF06385.12 ORZ01782.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Baculovirus LEF-11 protein PCMT PF01135.19 ORZ01782.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Nucleo_LEF-12 PF06256.11 ORZ01782.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein Methyltransf_23 PF13489.6 ORZ01783.1 - 3e-10 40.2 0.2 5.2e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ01783.1 - 7.6e-09 36.1 0.0 2.2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ01783.1 - 1.6e-08 35.1 0.1 7.2e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ01783.1 - 2.8e-08 34.4 0.0 8.8e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ01783.1 - 5.2e-06 26.3 0.0 9.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ01783.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 ORZ01783.1 - 0.051 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 ORZ01783.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase Ubie_methyltran PF01209.18 ORZ01783.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SelP_N PF04592.14 ORZ01783.1 - 2.5 7.4 11.5 3.8 6.8 11.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Methyltransf_11 PF08241.12 ORZ01784.1 - 3.3e-13 50.1 0.1 6.2e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ01784.1 - 2.5e-11 43.7 0.4 4.5e-11 42.9 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ01784.1 - 4e-11 43.5 0.0 8.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ01784.1 - 1.3e-10 41.2 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ01784.1 - 8.7e-10 39.2 0.1 1.7e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Nucleo_LEF-12 PF06256.11 ORZ01784.1 - 7e-05 22.7 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus LEF-12 protein MetW PF07021.12 ORZ01784.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ORZ01784.1 - 0.024 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 ORZ01784.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.18 ORZ01784.1 - 0.035 13.4 0.0 0.073 12.4 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1598 PF07643.11 ORZ01784.1 - 0.049 13.9 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) PMT2_N PF17987.1 ORZ01784.1 - 0.049 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal PCMT PF01135.19 ORZ01784.1 - 0.064 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zip PF02535.22 ORZ01784.1 - 0.9 8.7 7.3 1.2 8.2 7.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4460 PF14687.6 ORZ01785.1 - 1.9e-12 47.2 2.4 3.6e-12 46.3 1.6 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4460) HPS6 PF15702.5 ORZ01786.1 - 0.19 9.7 0.0 0.21 9.6 0.0 1.0 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein zf-C2H2 PF00096.26 ORZ01787.1 - 2e-13 49.9 11.3 2.1e-06 27.8 2.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ01787.1 - 3.1e-08 33.8 10.1 0.00014 22.4 1.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORZ01787.1 - 6.2e-06 26.4 16.0 0.0011 19.3 4.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ01787.1 - 0.00085 19.3 0.4 0.00085 19.3 0.4 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORZ01787.1 - 0.0034 17.5 1.7 0.39 10.8 0.2 2.1 1 1 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORZ01787.1 - 0.055 13.8 4.4 1.5 9.2 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 ORZ01787.1 - 0.092 13.5 4.9 2.7 8.8 1.7 2.3 1 1 1 2 2 2 0 CHORD zf-met PF12874.7 ORZ01787.1 - 0.1 13.0 3.1 0.9 10.0 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORZ01787.1 - 0.29 11.8 2.6 1.7 9.3 0.5 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain GCP_N_terminal PF17681.1 ORZ01788.1 - 2.1e-34 119.6 0.2 4.1e-34 118.6 0.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORZ01788.1 - 3.4e-26 92.4 5.5 3.4e-26 92.4 5.5 2.1 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal FRG1 PF06229.12 ORZ01789.1 - 1.8e-28 99.5 1.3 2.2e-28 99.3 1.3 1.0 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 ORZ01789.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 Fascin domain FMN_dh PF01070.18 ORZ01790.1 - 3.8e-124 414.2 0.0 6.5e-124 413.5 0.0 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORZ01790.1 - 1.9e-09 37.0 0.6 1.7e-07 30.6 0.1 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ORZ01790.1 - 6.1e-07 29.0 0.1 0.0053 16.1 0.0 2.6 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 ORZ01790.1 - 6.7e-05 22.2 0.0 0.00017 20.8 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 ORZ01790.1 - 0.0026 17.2 0.1 0.017 14.6 0.0 2.2 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.15 ORZ01790.1 - 0.044 13.2 0.2 0.13 11.6 0.3 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase TGT PF01702.18 ORZ01790.1 - 0.053 12.7 1.2 0.072 12.2 0.0 1.8 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase G3P_antiterm PF04309.12 ORZ01790.1 - 0.12 11.8 0.0 2 7.8 0.0 2.2 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator MWFE PF15879.5 ORZ01790.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit FMN_dh PF01070.18 ORZ01791.1 - 5.2e-124 413.8 0.0 9.4e-124 412.9 0.0 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORZ01791.1 - 2.3e-10 40.0 0.1 5.8e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORZ01791.1 - 4.5e-06 26.0 0.4 1.3e-05 24.5 0.1 1.8 2 1 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 ORZ01791.1 - 0.00085 18.8 0.1 0.008 15.7 0.0 2.4 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 ORZ01791.1 - 0.0011 18.3 0.1 0.83 8.9 0.0 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 ORZ01791.1 - 0.0034 16.8 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 ORZ01791.1 - 0.018 14.3 0.0 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Questin_oxidase PF14027.6 ORZ01792.1 - 5.6e-19 68.9 0.0 8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Questin oxidase-like Glyco_hydro_18 PF00704.28 ORZ01793.1 - 1.1e-24 87.7 0.8 2.3e-24 86.7 0.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORZ01793.1 - 0.0036 17.8 6.6 0.0036 17.8 6.6 5.7 6 0 0 6 6 6 2 Carbohydrate binding domain Metallophos PF00149.28 ORZ01794.1 - 4.8e-12 46.8 0.3 1.1e-11 45.7 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ARID PF01388.21 ORZ01795.1 - 1.1e-21 77.2 0.0 2.5e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 ORZ01795.1 - 0.24 10.7 0.3 1 8.6 0.1 1.8 1 1 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa F-box-like PF12937.7 ORZ01796.1 - 1.1e-08 34.8 1.2 1.1e-08 34.8 1.2 3.0 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 ORZ01796.1 - 9.6e-08 31.7 0.4 4.7e-07 29.5 0.4 2.2 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORZ01796.1 - 4.4e-05 23.2 0.5 0.19 11.8 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.7 ORZ01796.1 - 0.0024 18.2 16.5 1 9.9 0.1 6.5 5 2 2 7 7 7 2 Leucine Rich repeats (2 copies) TPR_14 PF13428.6 ORZ01796.1 - 0.034 14.9 8.3 19 6.4 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ORZ01796.1 - 0.059 13.4 0.1 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_2 PF07719.17 ORZ01796.1 - 0.12 12.5 7.2 1.6 9.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ01796.1 - 0.19 12.0 13.1 0.22 11.8 3.0 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ01796.1 - 0.36 11.1 4.2 0.96 9.7 0.5 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 F-box-like PF12937.7 ORZ01797.1 - 0.042 13.7 0.2 0.1 12.5 0.2 1.7 1 0 0 1 1 1 0 F-box-like Exo_endo_phos PF03372.23 ORZ01798.1 - 4.8e-20 72.1 0.3 8.5e-19 68.0 0.1 2.4 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 ORZ01798.1 - 1.5e-07 31.6 9.3 2.3e-05 24.6 0.8 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORZ01798.1 - 3.6e-07 29.8 12.7 1.3e-05 24.9 4.4 2.5 1 1 1 2 2 2 2 Leucine rich repeat XFP_C PF09363.10 ORZ01798.1 - 0.0079 15.7 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 XFP C-terminal domain LRR_9 PF14580.6 ORZ01798.1 - 0.038 13.5 0.5 0.082 12.4 0.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeat TFIIA PF03153.13 ORZ01798.1 - 0.19 11.7 14.2 0.31 11.0 14.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORZ01798.1 - 0.4 10.3 11.6 0.64 9.6 11.6 1.2 1 0 0 1 1 1 0 Spt20 family LRR_1 PF00560.33 ORZ01798.1 - 1.6 9.6 6.2 17 6.5 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Aminotran_1_2 PF00155.21 ORZ01799.1 - 5.9e-82 275.7 0.0 6.8e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MRP-L27 PF09809.9 ORZ01800.1 - 0.066 13.0 2.6 0.17 11.7 0.2 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L27 SET PF00856.28 ORZ01801.1 - 2.2e-10 41.2 0.0 4.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 SET domain bZIP_2 PF07716.15 ORZ01802.1 - 6.3e-13 48.6 7.0 6.3e-13 48.6 7.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORZ01802.1 - 0.0014 18.7 6.9 0.0033 17.5 6.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 ORZ01802.1 - 0.0023 18.0 20.3 0.0028 17.7 20.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit WD40_alt PF14077.6 ORZ01802.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif XhlA PF10779.9 ORZ01802.1 - 0.11 12.7 1.5 0.25 11.6 1.5 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Golgin_A5 PF09787.9 ORZ01802.1 - 0.14 11.6 22.6 0.22 11.0 22.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 P16-Arc PF04699.14 ORZ01802.1 - 0.72 10.3 8.6 1.2 9.6 8.6 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) CLN3 PF02487.17 ORZ01802.1 - 0.82 8.6 3.3 1.3 8.0 3.3 1.4 1 0 0 1 1 1 0 CLN3 protein HGTP_anticodon2 PF12745.7 ORZ01802.1 - 5.6 6.4 16.9 11 5.5 15.3 1.9 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Pex2_Pex12 PF04757.14 ORZ01803.1 - 6.4e-47 160.0 7.0 7.7e-47 159.8 7.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 ORZ01803.1 - 6.8e-07 29.0 1.4 1e-06 28.5 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORZ01803.1 - 2.6e-05 24.5 1.6 4.3e-05 23.8 1.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORZ01803.1 - 2.6e-05 23.9 1.4 4.7e-05 23.1 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ01803.1 - 0.00094 19.0 1.7 0.0015 18.3 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORZ01803.1 - 0.0052 16.9 5.1 0.0099 16.0 5.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORZ01803.1 - 0.018 15.0 4.3 0.033 14.2 4.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 ORZ01803.1 - 0.054 13.5 1.3 0.092 12.8 1.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon TTL PF03133.15 ORZ01804.1 - 1.9e-56 191.4 2.7 2.6e-56 190.9 2.7 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORZ01804.1 - 0.00043 19.6 0.0 0.012 14.9 0.0 2.3 2 1 0 2 2 2 2 YheC/D like ATP-grasp SRF-TF PF00319.18 ORZ01806.1 - 1.2e-05 24.7 15.1 2.9e+02 1.0 0.0 15.1 18 0 0 18 18 18 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1737 PF08410.10 ORZ01806.1 - 0.025 14.4 21.7 70 3.4 0.1 10.6 10 0 0 10 10 10 0 Domain of unknown function (DUF1737) GATase_2 PF00310.21 ORZ01807.1 - 2.5e-175 583.2 0.0 3.7e-175 582.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ORZ01807.1 - 2.2e-156 520.6 0.1 1.3e-154 514.8 0.0 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ORZ01807.1 - 1e-114 382.7 0.0 1.4e-113 379.1 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 ORZ01807.1 - 3.1e-84 281.3 4.4 5.1e-84 280.6 4.4 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 ORZ01807.1 - 6.8e-27 94.5 0.0 3.1e-26 92.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ORZ01807.1 - 1.8e-21 76.0 0.1 3.6e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 ORZ01807.1 - 1.3e-07 31.8 0.0 4.2e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORZ01807.1 - 2.6e-06 26.9 0.5 0.045 13.0 0.0 3.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORZ01807.1 - 1.2e-05 25.8 0.2 0.0057 17.2 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORZ01807.1 - 1.5e-05 24.3 0.0 0.0029 16.8 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ORZ01807.1 - 2.7e-05 23.9 0.3 0.0021 17.7 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORZ01807.1 - 6.4e-05 21.8 1.2 8.3e-05 21.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ORZ01807.1 - 0.00012 21.6 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORZ01807.1 - 0.00017 21.0 0.7 0.00079 18.8 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 ORZ01807.1 - 0.00047 20.5 0.0 0.89 10.0 0.0 3.1 3 0 0 3 3 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ORZ01807.1 - 0.0023 17.2 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORZ01807.1 - 0.0046 16.3 0.1 0.11 11.8 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 ORZ01807.1 - 0.022 13.8 1.3 0.12 11.4 1.3 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.19 ORZ01807.1 - 0.029 13.7 0.1 0.098 12.0 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORZ01807.1 - 0.032 14.3 0.0 23 5.1 0.0 3.5 4 0 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 ORZ01807.1 - 0.033 13.4 0.1 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 ORZ01807.1 - 0.055 12.5 0.1 0.35 9.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GATase_6 PF13522.6 ORZ01807.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain 3HCDH_N PF02737.18 ORZ01807.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 ORZ01807.1 - 6.5 6.6 5.5 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 Rossmann-like domain Kinesin PF00225.23 ORZ01808.1 - 1.4e-110 369.3 1.2 1.8e-110 369.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 ORZ01808.1 - 7.2e-46 156.6 5.7 7.2e-46 156.6 5.7 3.4 2 1 0 2 2 2 1 Kinesin-associated DUF3694 PF12473.8 ORZ01808.1 - 5.9e-32 111.5 0.4 2e-31 109.7 0.1 2.2 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 ORZ01808.1 - 3.8e-26 91.8 0.0 1.2e-25 90.2 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 ORZ01808.1 - 1e-12 48.4 0.1 4e-12 46.6 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 ORZ01808.1 - 2.1e-05 24.9 0.1 8.3e-05 22.9 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain KIF1B PF12423.8 ORZ01808.1 - 0.0025 18.2 0.3 0.01 16.3 0.3 2.1 1 0 0 1 1 1 1 Kinesin protein 1B DUF4085 PF13315.6 ORZ01808.1 - 0.071 12.7 7.3 0.022 14.4 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) AAA_22 PF13401.6 ORZ01808.1 - 1.1 9.6 7.3 8.9 6.6 0.0 4.6 5 0 0 5 5 5 0 AAA domain zf-C2H2_6 PF13912.6 ORZ02133.1 - 1.2e-05 25.2 0.5 2.2e-05 24.3 0.5 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORZ02133.1 - 0.00052 20.6 0.3 0.0017 19.0 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger RNF220 PF15926.5 ORZ02133.1 - 0.00074 19.2 0.6 0.028 14.0 0.6 2.0 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C2H2 PF00096.26 ORZ02133.1 - 0.002 18.5 0.3 0.005 17.2 0.3 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF4726 PF15855.5 ORZ02133.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) AAA PF00004.29 ORZ02134.1 - 6.3e-66 220.8 0.0 5.3e-37 127.2 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ02134.1 - 8.7e-18 63.9 0.0 6.2e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 AAA+ lid domain TIP49 PF06068.13 ORZ02134.1 - 5.6e-10 38.9 0.1 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 ORZ02134.1 - 1.3e-09 38.7 3.7 0.0024 18.3 0.1 3.9 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 ORZ02134.1 - 5.1e-09 36.5 2.2 0.0023 18.2 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORZ02134.1 - 5.3e-09 36.4 0.0 0.00051 20.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 ORZ02134.1 - 6e-09 35.8 0.0 7.7e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 ORZ02134.1 - 1e-08 35.1 0.0 0.005 16.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 ORZ02134.1 - 2.7e-08 34.4 0.0 0.00097 19.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORZ02134.1 - 5.5e-07 29.7 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORZ02134.1 - 7.2e-07 29.0 0.9 0.024 14.2 0.4 2.6 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORZ02134.1 - 1.5e-06 28.5 0.0 0.069 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 ORZ02134.1 - 2.8e-06 27.5 0.0 0.0001 22.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 ORZ02134.1 - 3.9e-06 26.9 0.0 0.0085 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 ORZ02134.1 - 6.9e-06 25.7 0.1 0.035 13.6 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein AAA_24 PF13479.6 ORZ02134.1 - 8.4e-06 25.6 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ORZ02134.1 - 1e-05 25.5 0.8 0.2 11.5 0.0 3.7 4 0 0 4 4 3 2 NACHT domain RNA_helicase PF00910.22 ORZ02134.1 - 2.4e-05 24.6 0.0 0.081 13.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase DUF2075 PF09848.9 ORZ02134.1 - 2.9e-05 23.5 0.0 0.066 12.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 ORZ02134.1 - 0.00011 22.6 0.0 0.031 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 ORZ02134.1 - 0.00013 21.4 0.3 0.13 11.6 0.0 3.1 2 1 1 3 3 3 1 DnaB-like helicase C terminal domain ABC_tran PF00005.27 ORZ02134.1 - 0.00018 22.1 0.0 0.22 12.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 ORZ02134.1 - 0.00026 20.9 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ORZ02134.1 - 0.00034 20.1 0.3 0.1 12.0 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ORZ02134.1 - 0.0013 18.1 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 KaiC AAA_3 PF07726.11 ORZ02134.1 - 0.0018 18.1 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 ORZ02134.1 - 0.003 17.6 0.0 0.51 10.3 0.0 2.8 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 ORZ02134.1 - 0.0034 17.2 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Hydin_ADK PF17213.3 ORZ02134.1 - 0.0041 17.4 1.0 2.8 8.2 0.0 2.9 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 ORZ02134.1 - 0.0065 16.2 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORZ02134.1 - 0.013 15.1 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORZ02134.1 - 0.017 14.4 0.1 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 ORZ02134.1 - 0.018 15.4 0.2 7.9 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ORZ02134.1 - 0.021 14.5 0.0 8.5 6.1 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 ORZ02134.1 - 0.046 13.6 0.0 4.6 7.1 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ResIII PF04851.15 ORZ02134.1 - 0.063 13.3 0.0 6.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Guanylate_kin PF00625.21 ORZ02134.1 - 0.068 12.9 0.0 3.3 7.3 0.0 2.5 1 1 1 2 2 2 0 Guanylate kinase NB-ARC PF00931.22 ORZ02134.1 - 0.076 12.2 0.1 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 ORZ02134.1 - 0.099 12.5 0.2 3.3 7.6 0.0 2.7 2 1 0 2 2 2 0 NTPase AAA_29 PF13555.6 ORZ02134.1 - 0.14 11.9 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 ORZ02134.1 - 0.14 11.9 0.1 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Parvo_NS1 PF01057.17 ORZ02134.1 - 0.18 10.9 0.0 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SNF2_N PF00176.23 ORZ02135.1 - 3.5e-48 164.1 1.3 6.6e-48 163.2 1.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORZ02135.1 - 8.6e-19 67.9 0.0 1.9e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ02135.1 - 3.4e-07 30.4 0.0 8.5e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 ORZ02135.1 - 5.8e-06 26.1 3.7 5.8e-06 26.1 3.7 2.6 3 0 0 3 3 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.6 ORZ02135.1 - 0.00053 19.7 0.5 0.00053 19.7 0.5 3.6 3 1 1 4 4 4 1 PHD/FYVE-zinc-finger like domain HDA2-3 PF11496.8 ORZ02135.1 - 0.0028 16.9 3.5 0.0067 15.6 1.9 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_19 PF13245.6 ORZ02135.1 - 0.0053 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain SnAC PF14619.6 ORZ02135.1 - 0.051 14.2 1.1 0.31 11.7 1.1 2.5 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex DUF1087 PF06465.13 ORZ02135.1 - 0.064 13.3 5.2 0.075 13.1 3.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF4258 PF14076.6 ORZ02135.1 - 0.086 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) C1_1 PF00130.22 ORZ02135.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.4 4 0 0 4 4 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 ORZ02135.1 - 1.4 8.9 22.8 0.028 14.3 4.2 3.4 2 1 1 3 3 3 0 PHD-finger DNA_pol_A_exo1 PF01612.20 ORZ02136.1 - 5e-48 163.1 0.6 9.2e-48 162.3 0.6 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 ORZ02136.1 - 2.6e-23 82.5 2.0 6.5e-23 81.2 0.9 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 ORZ02136.1 - 2.1e-11 43.6 0.0 8.6e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 HRDC domain Phage-tail_3 PF13550.6 ORZ02136.1 - 0.034 14.0 4.2 0.063 13.1 4.2 1.4 1 0 0 1 1 1 0 Putative phage tail protein DUF2959 PF11172.8 ORZ02136.1 - 0.17 12.0 1.6 0.58 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) SR-25 PF10500.9 ORZ02137.1 - 0.19 11.3 41.3 0.31 10.6 41.3 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 ORZ02137.1 - 1.2 8.8 30.7 0.14 11.8 26.3 1.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 RR_TM4-6 PF06459.12 ORZ02137.1 - 2.7 7.8 13.5 3.4 7.4 13.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 ORZ02137.1 - 3 6.0 23.6 3.4 5.8 23.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 ORZ02137.1 - 3.7 6.0 15.0 4 5.9 15.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Afi1 PF07792.12 ORZ02137.1 - 5 7.6 19.6 12 6.4 6.9 2.1 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 ORZ02137.1 - 7.6 5.6 15.2 8.4 5.5 15.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-RING_2 PF13639.6 ORZ02138.1 - 7.3e-12 45.4 7.6 7.3e-12 45.4 7.6 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORZ02138.1 - 1.1e-09 37.9 7.4 2.7e-09 36.7 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ02138.1 - 1.4e-08 34.5 6.8 3e-08 33.4 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ02138.1 - 1.5e-07 31.3 4.8 2.7e-07 30.4 4.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORZ02138.1 - 2.4e-06 27.5 1.8 2.4e-06 27.5 1.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORZ02138.1 - 3.6e-06 26.6 4.2 3.6e-06 26.6 4.2 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 ORZ02138.1 - 7.4e-06 25.7 8.3 1.4e-05 24.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORZ02138.1 - 4.8e-05 23.6 7.7 0.0002 21.6 7.7 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORZ02138.1 - 0.0001 22.1 7.9 0.00024 20.9 7.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORZ02138.1 - 0.00026 21.1 7.5 0.00063 19.9 7.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORZ02138.1 - 0.0074 16.1 5.4 0.018 14.8 5.1 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4542 PF15075.6 ORZ02138.1 - 0.091 13.2 0.1 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) Zn_ribbon_17 PF17120.5 ORZ02138.1 - 0.096 12.3 6.2 0.16 11.6 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 ORZ02138.1 - 0.21 11.3 6.1 0.59 9.8 6.1 1.8 1 1 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 ORZ02138.1 - 0.38 10.8 5.1 1 9.5 5.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 ORZ02138.1 - 0.43 10.9 4.3 7.4 7.0 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_10 PF16685.5 ORZ02138.1 - 0.92 9.7 5.8 1.8 8.7 5.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 ADH_N PF08240.12 ORZ02140.1 - 1.6e-24 85.8 2.5 1.6e-24 85.8 2.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ02140.1 - 7.5e-21 74.5 0.4 1.7e-20 73.3 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ02140.1 - 2e-05 25.6 0.0 4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORZ02140.1 - 0.002 17.5 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORZ02140.1 - 0.004 17.4 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ORZ02140.1 - 0.0065 15.8 0.5 0.011 15.0 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ORZ02140.1 - 0.073 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ORZ02140.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.18 ORZ02141.1 - 6.9e-05 22.9 11.6 6.9e-05 22.9 11.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORZ02141.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold SUIM_assoc PF16619.5 ORZ02141.1 - 0.26 11.4 16.3 1.8 8.7 6.9 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 ORZ02142.1 - 1.6e-27 95.1 2.0 2.3e-06 28.2 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ02142.1 - 1.5e-07 31.6 1.3 0.018 15.4 0.3 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORZ02142.1 - 5.5e-06 25.3 3.8 0.0052 15.5 1.1 2.3 2 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORZ02142.1 - 6.4e-06 25.7 0.5 7.8e-05 22.1 0.4 2.4 1 1 0 1 1 1 1 WD40-like domain Gmad1 PF10647.9 ORZ02142.1 - 0.0013 18.6 0.9 0.0023 17.8 0.9 1.4 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 ORZ02142.1 - 0.0052 15.8 1.3 0.5 9.3 0.3 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Bacteriocin_IIi PF11758.8 ORZ02142.1 - 0.01 15.7 0.7 0.024 14.5 0.7 1.6 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin GDPD PF03009.17 ORZ02142.1 - 0.1 12.3 0.6 0.59 9.8 0.1 2.2 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Ribosomal_S19 PF00203.21 ORZ02143.1 - 2.8e-22 78.4 0.0 3.3e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Abhydrolase_1 PF00561.20 ORZ02144.1 - 2e-48 165.3 0.0 1.7e-47 162.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORZ02144.1 - 7.9e-06 25.3 0.4 0.069 12.4 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 ORZ02144.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase STD1 PF17235.2 ORZ02145.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 STD1/MTH1 MFS_1 PF07690.16 ORZ02146.1 - 2.7e-29 102.2 27.9 2.7e-29 102.2 27.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ02146.1 - 5.7e-06 25.5 20.1 1.1e-05 24.5 17.5 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ02147.1 - 7.1e-30 104.1 31.8 7.1e-30 104.1 31.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 ORZ02147.1 - 0.066 12.9 0.3 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Npa1 PF11707.8 ORZ02148.1 - 1.5e-68 231.7 0.0 2.8e-68 230.8 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 ORZ02148.1 - 7.8e-43 146.4 3.5 1.1e-42 145.9 0.2 3.1 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 DUF4863 PF16155.5 ORZ02149.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) RPA_interact_C PF14768.6 ORZ02150.1 - 0.0042 17.6 9.1 0.0086 16.6 2.9 3.0 2 2 1 3 3 3 1 Replication protein A interacting C-terminal Glycogen_syn PF05693.13 ORZ02150.1 - 0.033 12.8 1.5 0.039 12.5 1.5 1.0 1 0 0 1 1 1 0 Glycogen synthase DZR PF12773.7 ORZ02150.1 - 1.1 9.4 5.7 0.3 11.1 0.7 2.2 2 0 0 2 2 2 0 Double zinc ribbon Cytochrom_CIII PF02085.16 ORZ02150.1 - 2 8.8 7.0 0.41 11.0 1.1 2.2 1 1 1 2 2 2 0 Class III cytochrome C family DnaJ_CXXCXGXG PF00684.19 ORZ02150.1 - 2.4 8.6 6.4 8.1 6.9 6.4 1.9 1 1 0 1 1 1 0 DnaJ central domain Cytochrome_C7 PF14522.6 ORZ02150.1 - 4.8 7.3 9.0 19 5.3 9.0 2.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c DASH_Hsk3 PF08227.11 ORZ02151.1 - 2.3e-05 24.7 1.5 3.9e-05 23.9 1.2 1.5 1 1 0 1 1 1 1 DASH complex subunit Hsk3 like FlxA PF14282.6 ORZ02151.1 - 0.0051 16.8 2.4 0.0061 16.5 2.4 1.2 1 0 0 1 1 1 1 FlxA-like protein DivIC PF04977.15 ORZ02151.1 - 0.027 14.2 0.2 0.038 13.7 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator YlbD_coat PF14071.6 ORZ02151.1 - 0.032 14.5 0.2 0.035 14.4 0.2 1.2 1 0 0 1 1 1 0 Putative coat protein DASH_Dad3 PF08656.10 ORZ02151.1 - 0.057 13.5 1.3 0.078 13.1 1.3 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad3 MRI PF15325.6 ORZ02152.1 - 0.076 14.1 0.7 0.092 13.8 0.7 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection MAPEG PF01124.18 ORZ02153.1 - 1.5e-24 86.3 0.9 1.7e-24 86.2 0.9 1.0 1 0 0 1 1 1 1 MAPEG family Abhydrolase_3 PF07859.13 ORZ02154.1 - 1.6e-62 211.2 0.3 2e-62 210.8 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORZ02154.1 - 2.9e-11 42.8 0.0 3.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ORZ02154.1 - 6.7e-09 35.1 0.4 1.9e-08 33.7 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORZ02154.1 - 0.0021 17.5 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family MFS_1 PF07690.16 ORZ02155.1 - 4.7e-40 137.6 31.1 2.5e-31 108.9 15.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORZ02155.1 - 1.7e-14 53.2 18.5 3e-14 52.4 18.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORZ02155.1 - 4e-14 52.3 4.2 4e-14 52.3 4.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ORZ02155.1 - 0.00019 20.0 4.3 0.00019 20.0 4.3 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector FH2 PF02181.23 ORZ02156.1 - 1.5e-83 281.0 8.2 1.5e-83 281.0 8.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORZ02156.1 - 2.1e-43 148.1 0.5 8.1e-43 146.2 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORZ02156.1 - 3.4e-38 131.2 1.1 3.4e-38 131.2 1.1 3.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain BLOC1_2 PF10046.9 ORZ02156.1 - 4.5 7.6 6.1 12 6.3 4.2 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 G-alpha PF00503.20 ORZ02157.1 - 3.4e-110 368.5 0.1 4e-110 368.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORZ02157.1 - 2.5e-16 59.7 0.3 2.5e-11 43.3 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORZ02157.1 - 0.00018 21.0 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORZ02157.1 - 0.0017 18.5 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SMP_C2CD2L PF18696.1 ORZ02157.1 - 0.1 12.4 0.2 0.86 9.4 0.0 2.1 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain AAA_29 PF13555.6 ORZ02157.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4524 PF15025.6 ORZ02158.1 - 0.13 12.0 0.4 9.1 6.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4524) Ribosomal_S19e PF01090.19 ORZ02159.1 - 0.044 13.5 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e Mon1 PF03164.14 ORZ02160.1 - 1.1e-146 489.1 2.2 1.2e-146 488.9 2.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Redoxin PF08534.10 ORZ02160.1 - 0.068 12.9 0.0 0.36 10.5 0.0 2.1 3 0 0 3 3 3 0 Redoxin SBDS_C PF09377.10 ORZ02161.1 - 7.5e-39 132.3 1.1 7.5e-39 132.3 1.1 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 ORZ02161.1 - 4.3e-35 119.6 1.4 9.3e-35 118.6 1.4 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.19 ORZ02161.1 - 0.041 13.2 0.1 0.48 9.8 0.0 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_22 PF13309.6 ORZ02161.1 - 0.076 13.1 0.9 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 HTH domain Myb_DNA-bind_3 PF12776.7 ORZ02161.1 - 0.082 13.9 0.9 0.37 11.8 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF956 PF06115.11 ORZ02161.1 - 0.15 11.8 0.7 1.3 8.8 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF956) HGTP_anticodon PF03129.20 ORZ02162.1 - 1e-23 83.2 0.0 4.6e-23 81.2 0.0 2.2 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORZ02162.1 - 1.9e-09 37.8 0.0 5.9e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) LRS4 PF10422.9 ORZ02162.1 - 0.093 12.3 0.2 0.22 11.0 0.2 1.6 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF1279 PF06916.13 ORZ02164.1 - 5.8e-19 68.4 0.1 8.1e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SNAP PF14938.6 ORZ02166.1 - 1.1e-101 340.0 18.6 1.3e-101 339.8 18.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 ORZ02166.1 - 9.3e-06 25.8 15.6 2.2e-05 24.6 0.2 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat NSF PF02071.20 ORZ02166.1 - 0.00012 22.1 16.7 5.4 8.2 0.6 6.4 6 0 0 6 6 6 3 Aromatic-di-Alanine (AdAR) repeat TPR_21 PF09976.9 ORZ02166.1 - 0.00013 21.7 1.6 0.00013 21.7 1.6 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain FTH PF01827.27 ORZ02166.1 - 0.0034 17.2 0.6 0.0071 16.1 0.6 1.5 1 0 0 1 1 1 1 FTH domain SAND PF01342.21 ORZ02166.1 - 0.037 13.7 0.2 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 SAND domain RPN7 PF10602.9 ORZ02166.1 - 0.089 12.5 5.1 0.064 13.0 2.7 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 ORZ02166.1 - 0.09 12.9 20.9 9.2 6.7 0.3 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ02166.1 - 0.27 12.0 11.4 53 4.7 0.0 6.2 5 1 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ02166.1 - 0.34 10.6 16.1 0.51 10.1 0.5 4.8 4 1 1 5 5 5 0 TPR repeat Homoserine_dh PF00742.19 ORZ02167.1 - 1.8e-47 161.5 0.0 2.5e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ORZ02167.1 - 1.1e-20 74.4 0.0 1.9e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ORZ02167.1 - 9.8e-05 22.8 0.0 0.00023 21.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORZ02167.1 - 0.00058 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 ORZ02167.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORZ02167.1 - 0.17 12.5 0.3 0.73 10.5 0.3 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 ORZ02167.1 - 0.19 11.1 2.1 0.43 9.9 2.0 1.6 2 0 0 2 2 2 0 ThiF family GCD14 PF08704.10 ORZ02168.1 - 5.3e-22 78.7 0.0 1.3e-21 77.4 0.0 1.4 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORZ02168.1 - 1.2e-07 31.7 0.0 1.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORZ02168.1 - 3e-07 30.4 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ02168.1 - 4.1e-07 30.6 0.0 8.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ORZ02168.1 - 0.00059 20.8 0.0 0.0012 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ02168.1 - 0.0016 19.1 0.0 0.0027 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ02168.1 - 0.008 16.0 0.0 0.014 15.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ02168.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 ORZ02168.1 - 0.048 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ02168.1 - 0.053 14.3 0.0 0.12 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ORZ02168.1 - 0.055 13.5 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 ORZ02168.1 - 0.058 12.4 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.17 ORZ02168.1 - 0.24 10.6 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Thg1 PF04446.12 ORZ02169.1 - 2.5e-52 176.2 0.1 3.4e-52 175.7 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 ORZ02169.1 - 7.2e-41 139.2 0.0 1.1e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Nop10p PF04135.12 ORZ02170.1 - 1e-23 83.1 1.1 1.2e-23 82.9 1.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Lactamase_B_6 PF16661.5 ORZ02171.1 - 5.3e-09 35.8 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORZ02171.1 - 0.003 16.8 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Uds1 PF15456.6 ORZ02172.1 - 1.4e-05 25.2 2.1 1.4e-05 25.2 2.1 8.3 6 3 2 8 8 8 3 Up-regulated During Septation DUF445 PF04286.12 ORZ02173.1 - 0.012 15.5 1.4 0.013 15.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YabA PF06156.13 ORZ02173.1 - 0.15 12.7 11.4 0.12 13.0 1.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA LMBR1 PF04791.16 ORZ02173.1 - 0.32 9.9 6.7 0.4 9.5 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TSC22 PF01166.18 ORZ02173.1 - 0.36 11.2 11.6 1.6 9.1 0.9 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family SHE3 PF17078.5 ORZ02173.1 - 0.47 10.1 18.4 1.5 8.4 7.4 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Ax_dynein_light PF10211.9 ORZ02173.1 - 0.52 10.2 19.9 0.47 10.4 3.0 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain DUF3452 PF11934.8 ORZ02173.1 - 0.92 9.1 3.9 0.71 9.4 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) GAS PF13851.6 ORZ02173.1 - 3.3 7.0 23.0 1.2 8.4 5.3 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Med9 PF07544.13 ORZ02173.1 - 5.3 7.2 12.7 15 5.8 4.0 3.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 JIP_LZII PF16471.5 ORZ02173.1 - 6.7 7.0 11.9 9.1 6.5 4.1 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 ORZ02173.1 - 7.1 6.8 26.8 0.3 11.3 3.4 2.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Glycos_transf_1 PF00534.20 ORZ02174.1 - 8.5e-23 80.8 0.0 2e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORZ02174.1 - 1e-14 55.1 0.0 2.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORZ02174.1 - 0.00023 21.5 0.0 0.00058 20.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2724 PF10893.8 ORZ02174.1 - 0.039 13.8 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) APG9 PF04109.16 ORZ02175.1 - 9.3e-173 575.6 4.7 1.1e-172 575.3 4.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF2231 PF09990.9 ORZ02175.1 - 0.22 12.0 0.2 0.22 12.0 0.2 2.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) Aldedh PF00171.22 ORZ02177.1 - 5.9e-98 328.4 0.1 7.4e-98 328.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sel1 PF08238.12 ORZ02179.1 - 1e-15 57.8 5.2 0.00078 20.1 0.6 4.3 4 0 0 4 4 4 4 Sel1 repeat MINDY_DUB PF04424.13 ORZ02179.1 - 0.093 12.8 0.0 1.5 8.8 0.0 2.2 1 1 1 2 2 2 0 MINDY deubiquitinase Inv-AAD PF18785.1 ORZ02180.1 - 5e-31 107.3 0.6 6e-30 103.7 0.6 2.0 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ORZ02180.1 - 9.5e-20 70.4 0.3 1.3e-19 69.9 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORZ02180.1 - 3.7e-05 23.5 0.1 4.9e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 ORZ02180.1 - 0.00021 21.3 0.1 0.00031 20.7 0.1 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 ORZ02180.1 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 1 1 0 1 1 1 0 APOBEC3 SNAD4 PF18750.1 ORZ02180.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.6 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 ICL PF00463.21 ORZ02181.1 - 4.7e-262 870.1 1.5 5.5e-262 869.9 1.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORZ02181.1 - 1.4e-09 37.7 0.1 8.9e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4177 PF13783.6 ORZ02182.1 - 0.069 13.5 0.0 0.081 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Aldo_ket_red PF00248.21 ORZ02183.1 - 9.8e-09 34.8 0.0 1.3e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-binding PF00249.31 ORZ02185.1 - 1.2e-12 47.8 0.2 8.6e-05 22.7 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORZ02185.1 - 8.4e-10 38.8 0.1 6e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 ORZ02185.1 - 0.0053 16.6 0.0 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Myb_DNA-bind_4 PF13837.6 ORZ02185.1 - 0.02 15.2 1.4 1.3 9.5 0.1 2.9 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORZ02185.1 - 0.094 12.9 1.1 6.9 6.9 0.0 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 PX PF00787.24 ORZ02186.1 - 3.2e-23 81.9 0.2 8.5e-23 80.5 0.2 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ORZ02186.1 - 1e-17 64.5 7.0 4.8e-11 42.7 0.5 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 ORZ02186.1 - 2.3e-06 27.5 0.7 0.016 14.9 0.7 2.3 1 1 0 1 1 1 1 BAR domain of APPL family DUF16 PF01519.16 ORZ02186.1 - 0.0018 18.7 1.3 1.7 9.2 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function DUF16 Sec34 PF04136.15 ORZ02186.1 - 0.016 15.1 0.3 0.038 13.9 0.3 1.7 1 0 0 1 1 1 0 Sec34-like family CENP-F_leu_zip PF10473.9 ORZ02186.1 - 0.097 12.7 4.6 0.36 10.9 0.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 ORZ02186.1 - 0.15 12.8 2.0 9.5 7.0 0.0 3.2 2 1 1 3 3 3 0 Occludin homology domain NPV_P10 PF05531.12 ORZ02186.1 - 0.25 11.8 0.7 3 8.4 0.0 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SHE3 PF17078.5 ORZ02186.1 - 0.68 9.6 5.2 2.2 7.9 0.4 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ILVD_EDD PF00920.21 ORZ02187.1 - 4.4e-221 735.0 0.5 4.9e-221 734.8 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family UTP25 PF06862.12 ORZ02188.1 - 6.8e-184 612.1 9.9 9.1e-184 611.6 9.9 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 zf-C3HC4_2 PF13923.6 ORZ02189.1 - 1.9e-07 30.8 7.9 6.6e-07 29.1 7.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 ORZ02189.1 - 2.2e-07 31.4 20.9 3.2e-06 27.7 2.2 4.4 2 2 2 4 4 4 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 ORZ02189.1 - 1.8e-06 27.7 4.9 5.2e-06 26.2 4.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORZ02189.1 - 8.8e-06 25.8 8.7 3.1e-05 24.0 8.7 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 ORZ02189.1 - 1.6e-05 25.1 7.0 1.6e-05 25.1 7.0 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORZ02189.1 - 2.5e-05 24.0 7.3 8e-05 22.4 7.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORZ02189.1 - 2.8e-05 23.9 2.4 7.6e-05 22.5 2.4 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Sina PF03145.16 ORZ02189.1 - 4.8e-05 23.4 15.1 0.0091 16.0 1.5 3.2 1 1 2 3 3 3 3 Seven in absentia protein family zf-RING_5 PF14634.6 ORZ02189.1 - 0.00051 19.9 6.6 0.0015 18.4 6.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORZ02189.1 - 0.00056 19.9 2.8 0.00056 19.9 2.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 ORZ02189.1 - 0.0017 18.4 6.0 0.0017 18.4 6.0 2.5 2 1 1 3 3 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ORZ02189.1 - 0.0023 17.8 6.8 0.0077 16.1 6.8 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 ORZ02189.1 - 0.0029 18.0 0.7 0.0029 18.0 0.7 3.2 2 1 1 3 3 3 1 TRAF-like zinc-finger zf-rbx1 PF12678.7 ORZ02189.1 - 0.0043 17.3 3.7 0.0043 17.3 3.7 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain DUF2514 PF10721.9 ORZ02189.1 - 0.014 15.4 0.8 0.033 14.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) zf-RING_14 PF17978.1 ORZ02189.1 - 0.022 15.2 1.5 0.048 14.1 1.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DASH_Spc19 PF08287.11 ORZ02189.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Spc19 CCDC92 PF14916.6 ORZ02189.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function zf-P11 PF03854.14 ORZ02189.1 - 1.7 8.4 10.2 0.12 12.1 4.4 2.0 2 0 0 2 2 2 0 P-11 zinc finger UBZ_FAAP20 PF15750.5 ORZ02189.1 - 6.3 6.8 11.8 0.75 9.8 0.2 4.1 3 1 1 4 4 4 0 Ubiquitin-binding zinc-finger SlyX PF04102.12 ORZ02191.1 - 0.13 12.9 1.3 0.22 12.2 0.0 2.2 2 0 0 2 2 2 0 SlyX Heliorhodopsin PF18761.1 ORZ02191.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Heliorhodopsin CCDC53 PF10152.9 ORZ02191.1 - 0.2 12.1 2.8 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3808 PF10300.9 ORZ02192.1 - 6.6e-60 203.2 3.3 1.1e-58 199.1 3.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) HemY_N PF07219.13 ORZ02192.1 - 0.17 12.1 0.2 3.5 7.9 0.1 2.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF4291 PF14124.6 ORZ02194.1 - 7.3e-58 195.4 0.9 9.1e-58 195.1 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) YukC PF10140.9 ORZ02194.1 - 0.032 13.1 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Fes1 PF08609.10 ORZ02195.1 - 8.3e-23 81.1 2.8 8.3e-23 81.1 2.8 2.4 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 ORZ02195.1 - 1.8e-06 27.8 0.0 0.002 18.1 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORZ02195.1 - 9.8e-06 25.4 0.0 0.026 14.8 0.0 3.2 3 0 0 3 3 2 2 HEAT repeat HEAT_2 PF13646.6 ORZ02195.1 - 1.1e-05 25.7 0.1 0.0023 18.3 0.0 3.1 3 2 0 3 3 3 1 HEAT repeats V-ATPase_H_C PF11698.8 ORZ02195.1 - 8.9e-05 22.6 3.2 0.14 12.3 0.0 3.3 1 1 1 3 3 3 2 V-ATPase subunit H HEAT_EZ PF13513.6 ORZ02195.1 - 0.00024 21.5 0.1 0.0035 17.8 0.0 2.7 1 1 1 2 2 2 1 HEAT-like repeat CDC14 PF08045.11 ORZ02195.1 - 0.0021 17.2 0.6 1.8 7.6 0.0 2.7 3 0 0 3 3 3 2 Cell division control protein 14, SIN component V-ATPase_H_N PF03224.14 ORZ02195.1 - 0.015 14.6 2.2 0.25 10.6 1.8 2.1 1 1 1 2 2 2 0 V-ATPase subunit H DUF4704 PF15787.5 ORZ02195.1 - 0.018 14.3 0.4 0.05 12.8 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4704) DUF3730 PF12530.8 ORZ02195.1 - 0.038 13.5 0.1 0.093 12.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3730) BCA_ABC_TP_C PF12399.8 ORZ02195.1 - 0.068 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter RICTOR_V PF14668.6 ORZ02195.1 - 0.075 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 SAPI PF16560.5 ORZ02195.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative mobile pathogenicity island SlyX PF04102.12 ORZ02196.1 - 0.11 13.1 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 SlyX Heliorhodopsin PF18761.1 ORZ02196.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Heliorhodopsin Ssl1 PF04056.14 ORZ02197.1 - 8.1e-81 270.4 0.0 1e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 ORZ02197.1 - 1.7e-17 63.4 25.1 3.3e-17 62.4 13.1 2.4 2 0 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 ORZ02197.1 - 1.7e-13 51.2 0.0 5.6e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 ORZ02197.1 - 4.6e-06 26.3 0.7 6.9e-06 25.8 0.7 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA PF00092.28 ORZ02197.1 - 0.00015 22.1 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain TackOD1 PF18551.1 ORZ02197.1 - 0.49 10.0 19.3 0.35 10.5 2.7 3.3 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 zinc_ribbon_10 PF10058.9 ORZ02197.1 - 0.51 10.1 7.3 1 9.2 0.5 2.7 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_15 PF17032.5 ORZ02197.1 - 8.1 7.3 17.2 0.18 12.5 8.0 2.2 1 1 1 2 2 2 0 zinc-ribbon family F-box-like PF12937.7 ORZ02198.1 - 1.2e-09 37.9 0.7 3.1e-09 36.6 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ02198.1 - 6.5e-09 35.5 0.4 2.2e-08 33.8 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORZ02198.1 - 0.0099 15.8 0.1 0.031 14.2 0.1 2.0 1 1 0 1 1 1 1 F-box Mucin PF01456.17 ORZ02198.1 - 0.015 15.3 7.4 0.015 15.3 7.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein PRANC PF09372.10 ORZ02198.1 - 0.2 12.0 0.0 0.47 10.8 0.0 1.6 1 0 0 1 1 1 0 PRANC domain DUF3439 PF11921.8 ORZ02198.1 - 3 7.8 12.9 0.43 10.6 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 ORZ02198.1 - 3.2 5.6 7.2 0.66 7.9 3.2 1.7 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Arf PF00025.21 ORZ02199.1 - 9.2e-67 223.8 0.8 1.1e-66 223.6 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORZ02199.1 - 8.4e-15 54.7 0.1 9.8e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ02199.1 - 9.7e-15 54.8 0.4 1.4e-14 54.4 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORZ02199.1 - 1.6e-11 43.9 0.2 2.1e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORZ02199.1 - 4.6e-09 35.9 0.6 9.7e-06 25.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 ORZ02199.1 - 2.6e-08 33.9 0.1 3.8e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORZ02199.1 - 8.8e-06 25.2 0.2 1e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORZ02199.1 - 0.00024 20.7 0.6 0.04 13.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 ORZ02199.1 - 0.0059 16.2 1.5 0.35 10.4 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORZ02199.1 - 0.0075 15.3 0.3 0.056 12.4 0.2 2.3 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 ORZ02199.1 - 0.032 14.0 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 ORZ02199.1 - 0.04 13.5 1.3 0.12 11.9 1.3 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 ORZ02199.1 - 0.067 13.2 0.3 0.17 11.9 0.1 1.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 ORZ02199.1 - 0.082 13.4 0.1 0.15 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 ORZ02199.1 - 0.097 12.0 0.2 0.13 11.5 0.2 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.27 ORZ02199.1 - 0.15 12.6 1.3 0.36 11.3 1.3 1.5 1 1 0 1 1 1 0 ABC transporter Ribosomal_L7Ae PF01248.26 ORZ02200.1 - 1.4e-23 82.5 1.7 2.6e-23 81.5 0.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 ORZ02200.1 - 0.028 14.5 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Glyco_hydro_47 PF01532.20 ORZ02201.1 - 1.7e-133 445.9 0.7 3.9e-66 223.8 1.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 ORZ02201.1 - 2.9e-05 22.8 0.1 0.032 12.7 0.0 2.2 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 ORZ02201.1 - 0.041 13.1 0.0 6.2 5.9 0.0 2.8 2 1 1 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Sugar_tr PF00083.24 ORZ02202.1 - 3.2e-88 296.6 19.0 8.6e-88 295.2 19.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ02202.1 - 1.2e-15 57.3 32.3 1.9e-15 56.6 21.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORZ02202.1 - 0.22 9.9 8.6 0.11 10.9 2.0 2.4 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) PalH PF08733.10 ORZ02202.1 - 0.38 9.7 5.8 0.68 8.9 5.8 1.3 1 0 0 1 1 1 0 PalH/RIM21 CitMHS PF03600.16 ORZ02202.1 - 2.1 7.4 11.5 0.048 12.9 5.0 1.5 2 0 0 2 2 2 0 Citrate transporter Carboxyl_trans PF01039.22 ORZ02203.1 - 2.5e-70 237.5 0.0 3e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain RRM_1 PF00076.22 ORZ02204.1 - 3.5e-25 87.6 0.0 3e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ02204.1 - 0.0095 16.0 0.0 4.2 7.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif PseudoU_synth_2 PF00849.22 ORZ02205.1 - 2.4e-31 109.0 0.1 4.8e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ORZ02205.1 - 0.025 14.3 0.2 0.055 13.2 0.2 1.6 1 0 0 1 1 1 0 S4 domain Mg_trans_NIPA PF05653.14 ORZ02207.1 - 1.2e-96 323.3 23.6 1.6e-96 322.9 23.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORZ02207.1 - 7.6e-05 22.9 8.2 7.6e-05 22.9 8.2 3.8 3 1 0 3 3 3 2 EamA-like transporter family FTR1 PF03239.14 ORZ02209.1 - 2.6e-73 246.9 14.1 3.2e-73 246.6 14.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Rab5ip PF07019.12 ORZ02209.1 - 0.022 15.3 3.5 0.022 15.3 3.5 3.3 3 1 0 3 3 3 0 Rab5-interacting protein (Rab5ip) MgtE PF01769.16 ORZ02209.1 - 0.2 12.0 15.8 1.4 9.3 0.8 3.3 3 0 0 3 3 3 0 Divalent cation transporter SPC25 PF06703.11 ORZ02209.1 - 1 9.1 0.0 1 9.1 0.0 2.5 3 1 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Cu-oxidase_2 PF07731.14 ORZ02210.1 - 3.7e-43 146.5 7.9 1.4e-40 138.2 0.4 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORZ02210.1 - 1.6e-36 124.9 13.9 2.2e-36 124.5 1.4 4.1 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORZ02210.1 - 2.6e-31 108.9 6.2 4.7e-29 101.5 1.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase HECT PF00632.25 ORZ02211.1 - 3.7e-88 296.0 0.0 2.6e-87 293.2 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Peptidase_C58 PF03543.14 ORZ02211.1 - 0.13 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen ACOX PF01756.19 ORZ02212.1 - 3e-31 108.4 0.0 7e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORZ02212.1 - 1.1e-17 64.7 0.5 3.3e-17 63.2 0.1 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORZ02212.1 - 8.6e-16 57.9 0.1 1.5e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SATase_N PF06426.14 ORZ02212.1 - 0.0066 16.8 0.2 24 5.4 0.0 3.4 2 1 1 3 3 3 1 Serine acetyltransferase, N-terminal DUF469 PF04320.14 ORZ02212.1 - 0.031 15.1 0.1 18 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein with unknown function (DUF469) BRE PF06113.12 ORZ02213.1 - 0.0098 14.8 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Polysacc_syn_2C PF08485.10 ORZ02213.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Ribosomal_S13 PF00416.22 ORZ02214.1 - 1.7e-54 183.6 2.1 2.4e-54 183.2 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORZ02214.1 - 0.0061 15.4 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF5326 PF17260.2 ORZ02215.1 - 0.043 13.9 0.1 0.057 13.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Herpes_gE PF02480.16 ORZ02215.1 - 0.066 12.0 0.0 0.069 11.9 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 ORZ02215.1 - 0.083 13.8 0.0 0.11 13.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 ORZ02215.1 - 0.19 10.5 0.0 0.2 10.5 0.0 1.0 1 0 0 1 1 1 0 Amnionless AMP-binding PF00501.28 ORZ02216.1 - 3.3e-95 319.2 0.0 4.2e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ02216.1 - 2e-15 57.5 0.1 4.9e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1752 PF08550.10 ORZ02218.1 - 1.8e-14 53.3 4.4 3.2e-14 52.5 4.4 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) YL1 PF05764.13 ORZ02218.1 - 0.041 14.0 2.3 0.063 13.4 2.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 ORZ02218.1 - 0.071 11.3 2.4 0.093 10.9 2.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORZ02218.1 - 0.56 8.4 3.6 0.72 8.1 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 ORZ02218.1 - 1.1 8.6 8.4 1.6 8.1 8.4 1.1 1 0 0 1 1 1 0 SDA1 Astro_capsid_p PF12226.8 ORZ02218.1 - 1.4 8.0 7.6 2 7.5 7.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM176 PF14851.6 ORZ02218.1 - 2 8.1 5.9 2.4 7.8 4.1 1.9 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 ORZ02218.1 - 3.2 7.5 7.9 9.1 6.0 7.8 1.9 1 1 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 ORZ02218.1 - 7 7.1 15.1 14 6.1 15.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 ORZ02218.1 - 9.6 4.2 12.8 13 3.8 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2046 PF09755.9 ORZ02219.1 - 3.2e-41 141.5 36.0 4.6e-31 108.2 23.1 3.3 1 1 2 3 3 3 3 Uncharacterized conserved protein H4 (DUF2046) Baculo_PEP_C PF04513.12 ORZ02219.1 - 1.3 9.1 12.7 5.7 7.0 1.5 2.7 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus mit_SMPDase PF14724.6 ORZ02220.1 - 3.2e-09 35.4 0.0 2.7e-05 22.4 0.1 3.2 3 1 1 4 4 4 3 Mitochondrial-associated sphingomyelin phosphodiesterase Sporozoite_P67 PF05642.11 ORZ02220.1 - 0.36 8.8 0.7 0.52 8.3 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DEAD PF00270.29 ORZ02221.1 - 1.6e-43 148.5 0.6 2.4e-43 147.9 0.2 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ02221.1 - 4.5e-33 113.9 0.0 2.7e-32 111.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 ORZ02221.1 - 4.7e-05 23.2 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORZ02221.1 - 4.8e-05 23.4 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORZ02221.1 - 0.00019 21.8 0.7 0.0047 17.3 0.4 2.4 2 1 0 2 2 2 1 AAA domain UTP25 PF06862.12 ORZ02221.1 - 0.00047 19.1 0.2 0.41 9.4 0.0 2.4 3 0 0 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 ORZ02221.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 ORZ02221.1 - 0.0078 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 ORZ02221.1 - 0.018 15.3 0.1 0.062 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain GMP_synt_C PF00958.22 ORZ02223.1 - 3.4e-42 142.4 0.1 7.8e-42 141.2 0.1 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ORZ02223.1 - 1.4e-37 129.4 0.0 2.3e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORZ02223.1 - 1.5e-12 47.7 0.2 3.2e-12 46.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 ORZ02223.1 - 3.3e-07 29.7 0.0 2.6e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 ORZ02223.1 - 0.0062 15.4 0.1 0.011 14.5 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 ORZ02223.1 - 0.035 13.6 0.1 0.31 10.5 0.0 2.3 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 ORZ02223.1 - 0.043 13.4 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) HOASN PF14515.6 ORZ02223.1 - 0.1 13.0 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices ATP_bind_3 PF01171.20 ORZ02223.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.19 ORZ02223.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family IL12 PF03039.14 ORZ02224.1 - 0.032 13.6 3.5 0.3 10.4 0.2 2.9 2 1 1 3 3 3 0 Interleukin-12 alpha subunit Coilin_N PF15862.5 ORZ02224.1 - 0.048 13.5 8.7 0.029 14.2 5.9 2.1 2 1 0 2 2 2 0 Coilin N-terminus Porph_ging PF09697.10 ORZ02224.1 - 0.42 11.2 2.1 1.7 9.2 2.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) TERB2 PF15101.6 ORZ02224.1 - 4.4 7.3 12.7 9.9 6.1 12.7 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2368 PF10166.9 ORZ02224.1 - 7.4 6.2 10.8 14 5.3 10.8 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) ubiquitin PF00240.23 ORZ02225.1 - 2.9e-19 68.6 0.0 4.7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORZ02225.1 - 3e-06 26.9 0.0 4.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 ORZ02225.1 - 3.4e-06 27.5 0.2 6.2e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain Ubiquitin_2 PF14560.6 ORZ02225.1 - 0.0014 19.1 0.0 0.0039 17.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 ORZ02225.1 - 0.076 13.6 0.1 0.13 12.9 0.1 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORZ02225.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sec66 PF09802.9 ORZ02226.1 - 1.6e-46 158.2 2.6 1.6e-46 158.2 2.6 1.7 1 1 1 2 2 2 1 Preprotein translocase subunit Sec66 DUF1451 PF07295.11 ORZ02226.1 - 0.067 13.2 0.3 0.067 13.2 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon containing domain RR_TM4-6 PF06459.12 ORZ02226.1 - 0.4 10.5 16.0 0.48 10.2 16.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 ORZ02226.1 - 0.53 10.0 10.2 0.66 9.7 10.2 1.1 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.12 ORZ02226.1 - 2.4 8.4 11.7 2.8 8.1 11.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 ORZ02226.1 - 3 7.8 7.4 3.7 7.5 7.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 ORZ02226.1 - 3.3 7.8 6.9 4.1 7.5 6.9 1.2 1 0 0 1 1 1 0 DDHD domain RdRP PF05183.12 ORZ02227.1 - 8.9e-126 420.9 0.0 1.3e-125 420.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Chrome_Resist PF09828.9 ORZ02227.1 - 0.065 13.7 0.5 0.24 11.8 0.5 2.0 1 1 0 1 1 1 0 Chromate resistance exported protein NUDE_C PF04880.13 ORZ02227.1 - 5 7.6 7.2 19 5.7 7.2 2.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Sds3 PF08598.11 ORZ02229.1 - 0.00025 21.1 0.1 0.00042 20.4 0.1 1.4 1 0 0 1 1 1 1 Sds3-like CGI-121 PF08617.10 ORZ02233.1 - 7.6e-45 152.9 0.0 8.4e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 RbsD_FucU PF05025.13 ORZ02233.1 - 0.095 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 RbsD / FucU transport protein family APH PF01636.23 ORZ02234.1 - 8e-48 163.4 0.0 1e-47 163.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORZ02234.1 - 7.7e-06 25.4 0.0 5.5e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 ORZ02234.1 - 0.00095 18.8 0.0 0.055 13.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 ORZ02234.1 - 0.0035 16.6 0.0 0.062 12.5 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 ORZ02234.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 ORZ02234.1 - 0.033 13.1 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) CRAL_TRIO PF00650.20 ORZ02235.1 - 1.6e-35 122.2 0.0 2.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORZ02235.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORZ02235.1 - 0.0095 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PHD PF00628.29 ORZ02236.1 - 1.9e-07 30.8 5.6 1.9e-07 30.8 5.6 2.0 1 1 1 2 2 2 2 PHD-finger zf-CpG_bind_C PF12269.8 ORZ02236.1 - 0.0001 22.1 2.2 0.014 15.2 0.4 2.4 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain AT_hook PF02178.19 ORZ02236.1 - 0.017 14.9 3.4 0.047 13.6 3.4 1.8 1 0 0 1 1 1 0 AT hook motif PspB PF06667.12 ORZ02236.1 - 0.1 12.6 1.5 0.47 10.5 1.5 2.1 1 1 0 1 1 1 0 Phage shock protein B zf-PHD-like PF15446.6 ORZ02236.1 - 0.1 12.2 0.3 0.1 12.2 0.3 2.5 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 ORZ02236.1 - 0.38 10.9 5.1 3.4 7.8 0.4 2.7 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 ORZ02236.1 - 0.85 9.5 8.8 0.26 11.2 1.2 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CAP_N PF01213.19 ORZ02237.1 - 0.63 9.5 16.6 0.82 9.1 1.2 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Caskin-Pro-rich PF16907.5 ORZ02237.1 - 3.4 8.2 12.0 1.6 9.3 1.0 2.6 2 0 0 2 2 2 0 Proline rich region of Caskin proteins CopD PF05425.13 ORZ02238.1 - 0.038 14.4 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 Copper resistance protein D MPS-4 PF17523.2 ORZ02238.1 - 0.24 11.6 5.7 0.32 11.1 0.5 2.8 2 1 1 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 adh_short_C2 PF13561.6 ORZ02239.1 - 1e-52 179.1 0.6 1.4e-52 178.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORZ02239.1 - 8.1e-49 165.7 0.2 1.1e-48 165.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORZ02239.1 - 3e-10 40.3 0.2 4.4e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORZ02239.1 - 0.015 14.7 0.1 0.03 13.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORZ02239.1 - 0.043 13.0 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 ORZ02239.1 - 0.054 14.1 0.1 0.14 12.7 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 ORZ02239.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cse1 PF08506.10 ORZ02240.1 - 1.9e-05 23.7 0.2 0.00026 20.0 0.0 2.7 4 0 0 4 4 4 1 Cse1 DRIM PF07539.12 ORZ02240.1 - 0.00053 18.4 4.7 0.0011 17.3 0.0 3.4 5 1 0 5 5 5 1 Down-regulated in metastasis Xpo1 PF08389.12 ORZ02240.1 - 0.0091 16.1 5.3 0.88 9.6 0.0 4.1 5 0 0 5 5 5 2 Exportin 1-like protein Cnd1 PF12717.7 ORZ02240.1 - 0.034 14.2 0.3 0.53 10.3 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORZ02240.1 - 0.074 13.6 1.5 2.4 8.8 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat DUF3385 PF11865.8 ORZ02240.1 - 0.1 12.5 0.8 16 5.3 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) RsbU_N PF08673.10 ORZ02240.1 - 0.41 10.8 1.6 2.9 8.1 0.0 3.2 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain HEAT PF02985.22 ORZ02240.1 - 1.1 9.7 5.1 12 6.5 0.0 5.1 7 0 0 7 7 7 0 HEAT repeat SET PF00856.28 ORZ02242.1 - 6.9e-06 26.5 11.9 0.00018 21.9 0.0 3.8 2 2 1 3 3 3 2 SET domain Zn_ribbon_2 PF12674.7 ORZ02242.1 - 0.43 11.3 0.1 0.43 11.3 0.1 4.2 3 2 2 5 5 5 0 Putative zinc ribbon domain ANAPC4_WD40 PF12894.7 ORZ02243.1 - 6.2e-13 48.9 0.0 0.0017 18.6 0.0 6.0 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORZ02243.1 - 1.2e-12 48.2 0.6 0.0041 17.9 0.0 6.7 6 1 0 7 7 7 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 ORZ02243.1 - 0.0026 16.4 0.1 0.0051 15.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 ORZ02243.1 - 0.22 11.5 1.2 7 6.7 0.0 3.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat ABC1 PF03109.16 ORZ02244.1 - 3.3e-31 107.9 0.1 6.4e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 ORZ02244.1 - 1.1e-06 28.3 0.1 6.3e-06 25.9 0.0 2.3 2 1 0 2 2 2 1 RIO1 family Pkinase PF00069.25 ORZ02244.1 - 0.0055 16.1 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORZ02244.1 - 0.0087 16.0 4.3 0.18 11.7 1.9 3.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 ORZ02244.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) GCV_T PF01571.21 ORZ02245.1 - 4.3e-84 281.9 0.0 6e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORZ02245.1 - 1.1e-21 76.6 0.2 2.5e-21 75.4 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 ORZ02245.1 - 0.0011 19.1 0.1 0.8 9.9 0.1 2.4 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family DUF3659 PF12396.8 ORZ02245.1 - 0.035 14.0 0.4 0.22 11.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3659) tRNA-synt_1e PF01406.19 ORZ02246.1 - 2.9e-135 450.4 2.0 4.2e-135 449.9 2.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ORZ02246.1 - 5.9e-12 45.0 1.4 3.1e-06 26.2 0.2 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORZ02246.1 - 2.2e-06 26.2 0.0 0.00037 18.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 ORZ02246.1 - 0.0028 16.6 0.8 0.024 13.6 0.1 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 ORZ02246.1 - 0.0055 15.7 0.1 0.62 8.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.11 ORZ02246.1 - 0.0078 16.7 0.1 0.036 14.5 0.0 2.2 2 0 0 2 2 2 1 DALR domain MFS_1_like PF12832.7 ORZ02247.1 - 4.2e-13 48.9 14.4 1.4e-12 47.1 14.4 1.8 1 1 0 1 1 1 1 MFS_1 like family Vma12 PF11712.8 ORZ02248.1 - 0.087 12.9 0.3 0.11 12.6 0.3 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Senescence PF06911.12 ORZ02249.1 - 1.7e-22 80.6 3.6 4e-22 79.4 3.6 1.7 1 0 0 1 1 1 1 Senescence-associated protein zinc_ribbon_16 PF17034.5 ORZ02256.1 - 7.9e-26 90.7 10.5 6.8e-25 87.7 10.8 2.3 1 1 1 2 2 2 1 Zinc-ribbon like family Nup84_Nup100 PF04121.13 ORZ02256.1 - 0.012 13.8 0.0 0.017 13.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 Zn_ribbon_17 PF17120.5 ORZ02256.1 - 0.042 13.5 14.9 0.022 14.4 11.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Zw10 PF06248.13 ORZ02258.1 - 8.4e-20 70.8 0.5 3e-13 49.2 0.0 2.5 1 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 ORZ02258.1 - 7.4e-10 38.9 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal IPK PF03770.16 ORZ02259.1 - 2.5e-49 167.8 0.0 3.9e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1720 PF08226.11 ORZ02259.1 - 0.26 11.7 7.6 1.8 9.0 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) LRR_6 PF13516.6 ORZ02260.1 - 3.7e-17 60.9 12.7 0.0051 16.8 0.1 7.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 ORZ02260.1 - 2e-06 27.5 0.6 7.9 7.5 0.0 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 ORZ02260.1 - 1.7e-05 25.1 7.2 1.3 9.6 0.8 5.5 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORZ02260.1 - 0.013 15.3 8.1 2 8.2 0.2 5.0 4 2 0 4 4 4 0 Leucine rich repeat Pes-10 PF07149.11 ORZ02260.1 - 1.2 8.1 11.5 1.7 7.6 11.5 1.2 1 0 0 1 1 1 0 Pes-10 Nop14 PF04147.12 ORZ02260.1 - 1.4 7.0 15.6 1.8 6.7 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 ORZ02260.1 - 3.5 7.0 16.2 4.9 6.5 16.2 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 ORZ02260.1 - 5.2 6.0 13.8 6.9 5.5 13.8 1.1 1 0 0 1 1 1 0 Paf1 COPI_C PF06957.11 ORZ02260.1 - 6.6 5.4 12.6 9.4 4.9 12.6 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus AA_permease_2 PF13520.6 ORZ02263.1 - 4.1e-55 187.3 51.0 5.1e-55 187.0 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORZ02263.1 - 1.8e-39 135.7 43.8 2.4e-39 135.3 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORZ02263.1 - 1.8e-06 27.9 6.9 1.8e-06 27.9 6.9 4.0 3 0 0 3 3 3 1 C-terminus of AA_permease DUF3341 PF11821.8 ORZ02263.1 - 0.071 12.8 0.1 0.071 12.8 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3341) DUF5437 PF17505.2 ORZ02263.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5437) DUF3094 PF11293.8 ORZ02263.1 - 0.32 10.8 1.1 16 5.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) tRNA-synt_2 PF00152.20 ORZ02264.1 - 2.4e-92 309.4 0.0 2.9e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORZ02264.1 - 1.6e-09 37.6 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORZ02264.1 - 0.029 13.8 0.1 2.3 7.6 0.0 2.7 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) WD40 PF00400.32 ORZ02265.1 - 7.8e-36 121.5 21.5 8.8e-07 29.5 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 ORZ02265.1 - 6.1e-16 58.1 0.9 1.3e-15 57.0 0.9 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 ORZ02265.1 - 2.4e-14 52.9 9.1 0.0024 16.6 0.1 6.1 1 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.33 ORZ02265.1 - 8.2e-11 41.5 0.3 2.1e-10 40.2 0.3 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORZ02265.1 - 8.8e-11 42.0 0.5 0.063 13.6 0.1 6.0 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ02265.1 - 5.2e-08 32.6 0.0 0.0058 16.0 0.0 3.2 2 1 1 3 3 3 3 WD40-like domain BBS2_Mid PF14783.6 ORZ02265.1 - 0.00022 21.2 0.0 0.65 10.1 0.0 3.9 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 ORZ02265.1 - 0.0063 16.4 5.4 0.085 12.8 0.2 3.8 3 1 1 4 4 4 1 F-box Auto_anti-p27 PF06677.12 ORZ02265.1 - 0.013 15.7 1.2 5.4 7.2 0.1 3.3 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF5046 PF16465.5 ORZ02265.1 - 0.054 12.9 0.0 4.8 6.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) HECT PF00632.25 ORZ02266.1 - 4.2e-97 325.3 0.0 5.9e-97 324.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORZ02266.1 - 7.9e-37 125.0 21.4 3.9e-13 49.2 1.9 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 ORZ02266.1 - 1.6e-20 73.3 0.7 3.8e-20 72.1 0.7 1.7 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 ORZ02266.1 - 0.083 12.9 15.7 0.12 12.3 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 ORZ02266.1 - 2.2 8.7 11.0 7.2 7.0 0.3 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RP-C_C PF11800.8 ORZ02266.1 - 8.9 6.3 11.5 0.087 12.9 3.4 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region MFS_1 PF07690.16 ORZ02267.1 - 1.1e-18 67.3 59.0 3.5e-09 36.0 38.2 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORZ02267.1 - 2e-06 26.5 28.2 6.8e-06 24.8 28.1 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORZ02267.1 - 3.3e-06 26.3 39.8 8e-05 21.7 20.6 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Bcl-2 PF00452.19 ORZ02268.1 - 0.004 17.8 0.8 6.9 7.4 0.0 3.7 3 0 0 3 3 3 2 Apoptosis regulator proteins, Bcl-2 family DnaJ_C PF01556.18 ORZ02269.1 - 1.4e-42 145.3 0.1 1.8e-42 144.9 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORZ02269.1 - 3.7e-25 87.8 3.8 6.2e-25 87.1 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORZ02269.1 - 1.9e-11 44.1 18.8 3.9e-11 43.2 18.8 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORZ02269.1 - 0.0012 18.8 12.6 0.0025 17.7 1.0 2.9 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein HicA_toxin PF07927.12 ORZ02269.1 - 0.087 12.9 0.1 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, HypA PF01155.19 ORZ02269.1 - 2.8 8.0 10.2 2.3 8.3 4.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Keratin_2_head PF16208.5 ORZ02269.1 - 6.5 6.9 21.0 2.6 8.2 15.1 2.2 2 0 0 2 2 2 0 Keratin type II head Arm PF00514.23 ORZ02270.1 - 6.1e-10 38.8 18.5 3.5e-06 26.9 0.1 7.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORZ02270.1 - 0.12 12.9 1.0 3.9 8.1 0.2 3.0 2 0 0 2 2 2 0 HEAT-like repeat NDUFA12 PF05071.16 ORZ02271.1 - 2.3e-09 38.0 7.5 1e-08 35.9 7.5 2.0 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4746 PF15928.5 ORZ02271.1 - 0.0029 17.1 11.4 0.0032 17.0 11.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) DUF3807 PF12720.7 ORZ02271.1 - 4.5 7.5 8.7 6.4 7.0 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Asp-B-Hydro_N PF05279.11 ORZ02271.1 - 5.2 7.1 10.1 6.5 6.7 10.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ion_trans PF00520.31 ORZ02272.1 - 2.5e-05 23.7 1.7 3.1e-05 23.3 1.7 1.1 1 0 0 1 1 1 1 Ion transport protein UPF0242 PF06785.11 ORZ02272.1 - 0.00096 19.3 7.3 0.0023 18.0 7.3 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus betaPIX_CC PF16523.5 ORZ02272.1 - 0.019 14.8 1.6 0.033 14.0 1.6 1.4 1 0 0 1 1 1 0 betaPIX coiled coil CDPS PF16715.5 ORZ02272.1 - 0.059 13.0 0.1 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase 60KD_IMP PF02096.20 ORZ02272.1 - 0.084 12.8 2.6 0.13 12.2 1.0 1.8 2 0 0 2 2 2 0 60Kd inner membrane protein ZapB PF06005.12 ORZ02272.1 - 0.19 12.2 9.9 0.42 11.1 9.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 ORZ02272.1 - 0.24 12.0 4.0 0.47 11.1 4.0 1.4 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 ORZ02272.1 - 2.3 8.1 9.5 9.4 6.1 9.0 2.0 1 1 0 1 1 1 0 Septum formation initiator PAAR_motif PF05488.13 ORZ02274.1 - 0.067 13.4 0.1 0.081 13.1 0.1 1.1 1 0 0 1 1 1 0 PAAR motif Nucleoporin_N PF08801.11 ORZ02275.1 - 9.1e-56 189.4 0.0 1.3e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ORZ02275.1 - 6.5e-13 48.3 1.0 1e-12 47.6 1.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal TraY PF05509.11 ORZ02275.1 - 0.069 13.2 0.1 0.32 11.1 0.1 2.2 1 1 0 1 1 1 0 TraY domain TPR_16 PF13432.6 ORZ02275.1 - 9.8 6.9 6.2 17 6.1 1.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 ORZ02276.1 - 8.9e-50 168.7 6.2 8.9e-50 168.7 6.2 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORZ02276.1 - 1.9e-36 125.5 1.3 1.9e-36 125.5 1.3 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORZ02276.1 - 7.3e-22 77.3 0.0 1.5e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORZ02276.1 - 1.3e-16 61.5 0.8 3.5e-14 53.6 0.0 3.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ02276.1 - 6.8e-15 54.5 0.0 1.5e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ02276.1 - 0.00032 20.5 0.7 0.00073 19.3 0.7 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CTP_transf_1 PF01148.20 ORZ02277.1 - 1.7e-43 149.3 1.4 2.3e-43 148.9 1.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ligase_CoA PF00549.19 ORZ02278.1 - 2.5e-21 76.1 0.4 4.9e-21 75.1 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 ORZ02278.1 - 3e-15 56.7 1.6 1.1e-14 54.8 0.1 2.5 2 1 1 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.6 ORZ02278.1 - 6.5e-11 42.2 0.1 6.5e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain PGM_PMM_II PF02879.16 ORZ02278.1 - 0.12 13.0 0.0 0.45 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DnaJ PF00226.31 ORZ02279.1 - 4.6e-25 87.5 0.4 1.6e-24 85.8 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 ORZ02279.1 - 2.3e-09 37.3 3.0 6e-09 36.0 3.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORZ02279.1 - 1.9e-06 28.1 3.4 3.7e-06 27.1 3.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORZ02279.1 - 0.00067 20.0 1.4 0.0019 18.5 1.4 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ORZ02281.1 - 0.017 15.5 1.5 0.031 14.7 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type CpXC PF14353.6 ORZ02281.1 - 0.025 14.6 0.3 0.13 12.3 0.4 2.0 1 1 0 1 1 1 0 CpXC protein zf-C2H2_4 PF13894.6 ORZ02281.1 - 0.036 14.9 0.3 0.099 13.5 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger BIR PF00653.21 ORZ02281.1 - 0.044 14.4 0.3 0.11 13.1 0.3 1.7 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain EAV_GP5 PF15981.5 ORZ02281.1 - 0.083 13.3 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 Envelope glycoprotein GP 5 of equine arteritis virus zf-C2H2_jaz PF12171.8 ORZ02281.1 - 0.09 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding VCBS PF13517.6 ORZ02282.1 - 8.8e-32 109.5 16.3 8.1e-10 39.1 0.4 6.3 4 1 2 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ORZ02282.1 - 1.1e-12 47.8 29.0 0.0037 17.4 0.0 8.1 7 1 1 8 8 8 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 ORZ02282.1 - 0.00058 19.3 7.2 1.5 8.1 0.0 6.0 6 1 1 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region G-gamma PF00631.22 ORZ02283.1 - 1.1e-19 70.2 0.1 1.2e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 GGL domain Iso_dh PF00180.20 ORZ02284.1 - 4.7e-82 275.9 0.0 5.6e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ANAPC3 PF12895.7 ORZ02285.1 - 2.8e-13 49.9 1.4 2.8e-13 49.9 1.4 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORZ02285.1 - 4.7e-13 48.2 3.2 9.5e-05 22.3 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ02285.1 - 5.1e-09 36.5 11.5 0.00049 20.6 0.0 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ02285.1 - 6.9e-08 32.7 8.4 0.086 13.7 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ02285.1 - 8.5e-07 28.5 7.3 0.00023 20.8 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ02285.1 - 5.7e-06 26.4 4.1 0.5 10.9 0.0 4.7 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ02285.1 - 1.6e-05 24.7 27.7 0.00032 20.6 0.3 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ02285.1 - 0.0021 18.7 16.9 3.1 8.5 1.1 4.8 4 1 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ02285.1 - 0.0026 17.4 7.9 0.47 10.2 0.0 4.2 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 ORZ02285.1 - 0.025 14.9 16.6 0.15 12.4 0.1 4.9 5 1 0 5 5 4 0 Tetratricopeptide repeat SNAP PF14938.6 ORZ02285.1 - 0.072 12.5 0.9 0.15 11.5 0.5 1.6 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 ORZ02285.1 - 0.092 12.8 10.9 1.1 9.5 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ02285.1 - 0.098 13.3 4.6 4 8.3 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF4404 PF14357.6 ORZ02285.1 - 0.21 12.3 1.6 1 10.1 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ANAPC8 PF04049.13 ORZ02285.1 - 0.22 11.6 1.2 12 6.0 0.2 2.8 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 SRP_TPR_like PF17004.5 ORZ02285.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.4 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_10 PF13374.6 ORZ02285.1 - 1.7 8.6 16.8 1.5 8.8 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Rho_GDI PF02115.17 ORZ02286.1 - 9.4e-66 221.3 0.2 1e-65 221.2 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Glyco_hydro_15 PF00723.21 ORZ02286.1 - 0.03 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Ribosomal_L12 PF00542.19 ORZ02287.1 - 2.3e-21 75.9 9.5 2.3e-21 75.9 9.5 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ORZ02287.1 - 2.9e-15 55.7 3.6 2.9e-15 55.7 3.6 4.0 5 0 0 5 5 5 1 Ribosomal protein L7/L12 dimerisation domain DUF2267 PF10025.9 ORZ02287.1 - 0.017 15.4 0.3 0.03 14.6 0.3 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Complex1_LYR PF05347.15 ORZ02288.1 - 5.3e-12 45.6 0.9 9e-12 44.9 0.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORZ02288.1 - 0.0089 16.8 0.1 0.014 16.2 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like ORC3_N PF07034.11 ORZ02289.1 - 0.59 9.2 1.5 1 8.4 1.5 1.5 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AdoHcyase PF05221.17 ORZ02290.1 - 5.5e-134 446.0 0.0 5e-130 433.0 0.0 2.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ORZ02290.1 - 8.7e-87 289.2 2.9 1.4e-86 288.6 2.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORZ02290.1 - 5.7e-10 38.8 0.2 1.1e-09 37.9 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORZ02290.1 - 2.6e-05 23.9 0.2 4.1e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ORZ02290.1 - 0.0018 18.5 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Rad17 PF03215.15 ORZ02293.1 - 2.2e-22 79.9 0.0 5.4e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 ORZ02293.1 - 0.00093 19.6 0.2 0.0041 17.5 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORZ02293.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 ORZ02293.1 - 0.011 16.3 0.0 0.052 14.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 ORZ02293.1 - 0.021 15.1 0.2 0.064 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain Aim21 PF11489.8 ORZ02293.1 - 0.058 12.3 0.4 7.5 5.3 0.1 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 21 NB-ARC PF00931.22 ORZ02293.1 - 0.13 11.5 0.1 5.6 6.1 0.2 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 ORZ02293.1 - 0.18 11.6 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Brix PF04427.18 ORZ02294.1 - 1.1e-40 139.8 0.1 1.5e-40 139.4 0.1 1.2 1 0 0 1 1 1 1 Brix domain Methyltr_RsmB-F PF01189.17 ORZ02295.1 - 1.1e-38 133.0 0.0 6.1e-38 130.5 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORZ02295.1 - 0.0054 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase ADH_N PF08240.12 ORZ02296.1 - 2.4e-30 104.6 0.2 3.8e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ02296.1 - 2.9e-28 98.4 0.0 4.5e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORZ02296.1 - 1.4e-11 44.3 0.9 1.1e-10 41.4 0.9 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORZ02296.1 - 0.0013 19.8 0.0 0.0022 19.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORZ02296.1 - 0.04 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FHA PF00498.26 ORZ02297.1 - 3.8e-16 59.2 0.0 7.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORZ02297.1 - 2.7e-11 43.0 8.5 2.7e-11 43.0 8.5 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORZ02297.1 - 2.9e-08 33.9 11.0 4.7e-08 33.2 11.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORZ02297.1 - 0.00088 19.2 10.2 0.0018 18.2 10.2 1.5 1 1 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 ORZ02297.1 - 0.0025 18.1 0.0 0.0049 17.2 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 ORZ02297.1 - 0.0055 16.6 10.9 0.0091 15.9 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORZ02297.1 - 0.026 14.5 2.8 0.045 13.8 2.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORZ02297.1 - 0.03 14.2 11.9 0.053 13.4 11.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORZ02297.1 - 0.034 14.5 8.7 0.081 13.2 8.7 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF1467 PF07330.12 ORZ02297.1 - 0.036 14.0 0.4 1 9.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) zf-C3HC4_3 PF13920.6 ORZ02297.1 - 0.074 12.9 8.2 0.12 12.2 8.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORZ02297.1 - 0.17 11.5 6.5 0.31 10.7 6.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORZ02297.1 - 0.21 11.5 8.3 0.59 10.0 8.5 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 ORZ02297.1 - 0.22 11.4 5.2 0.37 10.7 5.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 ORZ02297.1 - 0.27 11.3 12.2 0.098 12.7 9.0 1.9 1 1 1 2 2 2 0 RING-type zinc-finger RhoGAP PF00620.27 ORZ02298.1 - 2.7e-35 121.4 0.6 6.3e-35 120.3 0.6 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORZ02298.1 - 2.5e-27 94.9 45.6 1.4e-10 41.2 6.2 5.3 5 0 0 5 5 5 4 LIM domain SF1-HH PF16275.5 ORZ02299.1 - 1.1e-41 141.7 2.7 3.1e-41 140.2 2.7 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 ORZ02299.1 - 2.4e-08 33.7 10.2 0.0004 20.3 0.7 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 ORZ02299.1 - 1e-06 28.4 0.1 2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 KH domain DnaJ_CXXCXGXG PF00684.19 ORZ02299.1 - 0.012 16.0 4.3 0.031 14.6 4.3 1.7 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.6 ORZ02299.1 - 0.012 15.6 0.9 0.012 15.6 0.9 2.7 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 ORZ02299.1 - 0.017 15.0 9.6 0.045 13.6 0.4 2.9 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 ORZ02299.1 - 0.09 12.5 9.3 1.2 8.9 0.9 2.3 2 0 0 2 2 2 0 Zinc knuckle CCDC-167 PF15188.6 ORZ02299.1 - 6 7.3 6.1 7.6 7.0 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SOR_SNZ PF01680.17 ORZ02300.1 - 2.1e-112 373.9 5.5 2.1e-112 373.9 5.5 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 ORZ02300.1 - 1.2e-09 37.9 6.9 1e-07 31.6 0.2 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 ORZ02300.1 - 0.00029 20.0 1.9 0.13 11.3 0.0 2.5 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) NanE PF04131.14 ORZ02300.1 - 0.0064 15.7 0.3 0.14 11.3 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 ORZ02300.1 - 0.008 15.8 0.2 0.64 9.6 0.0 2.3 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family TetR_C_27 PF17935.1 ORZ02300.1 - 0.0082 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 ORZ02300.1 - 0.03 13.8 0.1 0.25 10.8 0.0 2.1 2 1 0 2 2 2 0 Histidine biosynthesis protein ketoacyl-synt PF00109.26 ORZ02301.1 - 7.9e-60 202.6 2.2 7.9e-60 202.6 2.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORZ02301.1 - 6.7e-37 126.1 2.6 6.7e-37 126.1 2.6 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ORZ02301.1 - 0.0012 18.3 1.7 0.0018 17.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ORZ02301.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension NIPSNAP PF07978.13 ORZ02302.1 - 7.5e-35 119.2 0.1 2.7e-23 82.1 0.0 2.5 2 0 0 2 2 2 2 NIPSNAP DUF3000 PF11452.8 ORZ02303.1 - 0.045 13.3 0.0 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3000) TUDOR_5 PF18359.1 ORZ02306.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 MFS_MOT1 PF16983.5 ORZ02307.1 - 2.5e-58 195.3 33.9 4e-33 114.1 5.3 3.7 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily COG6 PF06419.11 ORZ02308.1 - 6.6e-188 625.9 16.9 7.5e-188 625.7 16.9 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 NAPRTase_N PF17767.1 ORZ02308.1 - 0.066 13.6 1.1 1.4 9.3 0.2 2.7 1 1 1 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain BLOC1_2 PF10046.9 ORZ02308.1 - 0.089 13.1 3.9 0.14 12.4 1.1 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 STPPase_N PF16891.5 ORZ02308.1 - 0.12 12.8 0.1 0.65 10.5 0.1 2.3 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain MCU PF04678.13 ORZ02308.1 - 0.25 11.4 3.8 0.28 11.2 1.6 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Complex1_LYR_2 PF13233.6 ORZ02308.1 - 0.32 11.8 2.0 2.5 8.9 0.3 2.7 2 0 0 2 2 2 0 Complex1_LYR-like DASH_Duo1 PF08651.10 ORZ02308.1 - 0.46 10.3 3.6 3.2 7.6 3.0 2.9 4 0 0 4 4 4 0 DASH complex subunit Duo1 eIF3_N PF09440.10 ORZ02308.1 - 0.69 10.4 6.3 0.24 11.8 2.7 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Sec34 PF04136.15 ORZ02308.1 - 0.88 9.4 8.6 0.65 9.9 4.9 2.6 2 1 0 2 2 2 0 Sec34-like family BST2 PF16716.5 ORZ02308.1 - 2.3 8.9 10.4 0.42 11.2 5.8 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF1515 PF07439.11 ORZ02308.1 - 3.7 7.6 5.2 27 4.8 4.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF1722 PF08349.11 ORZ02308.1 - 5 7.4 7.5 1.1 9.6 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) Histone PF00125.24 ORZ02309.1 - 3.8e-19 69.3 0.1 4.7e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 ORZ02309.1 - 1e-12 47.5 0.7 1.9e-12 46.7 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 ORZ02309.1 - 0.0016 18.7 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Dcc1 PF09724.9 ORZ02310.1 - 3.5e-69 233.7 0.0 4.5e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 zf-RING_5 PF14634.6 ORZ02310.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain NmrA PF05368.13 ORZ02312.1 - 9e-15 54.9 0.0 1.4e-14 54.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORZ02312.1 - 9.1e-15 55.0 0.0 2e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ORZ02312.1 - 0.00093 19.6 0.3 0.0034 17.8 0.2 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORZ02312.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORZ02312.1 - 0.035 13.6 0.0 0.077 12.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORZ02312.1 - 0.05 13.7 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SpoU_sub_bind PF08032.12 ORZ02312.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding W2 PF02020.18 ORZ02313.1 - 1.1e-18 67.2 1.9 2.4e-18 66.0 0.7 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon HGTP_anticodon2 PF12745.7 ORZ02313.1 - 0.019 14.5 0.1 0.043 13.3 0.1 1.6 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF763 PF05559.11 ORZ02313.1 - 0.098 11.8 0.3 0.31 10.2 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF763) Prefoldin_3 PF13758.6 ORZ02313.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.2 3 0 0 3 3 3 0 Prefoldin subunit DUF596 PF04591.12 ORZ02313.1 - 0.15 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF596 FANCI_S4 PF14678.6 ORZ02314.1 - 1.1e-45 155.7 0.3 6.8e-45 153.2 0.1 2.5 3 0 0 3 3 3 1 FANCI solenoid 4 FANCI_S2 PF14676.6 ORZ02314.1 - 7.8e-41 140.1 1.2 7.8e-41 140.1 1.2 3.6 3 0 0 3 3 3 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 ORZ02314.1 - 8.2e-35 120.2 0.7 2.5e-34 118.6 0.7 1.8 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S1 PF14675.6 ORZ02314.1 - 2.7e-28 99.1 0.8 3.5e-27 95.4 0.4 3.2 2 1 0 2 2 2 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 ORZ02314.1 - 6.9e-18 64.4 0.3 4.4e-17 61.8 0.3 2.5 1 0 0 1 1 1 1 FANCI helical domain 1 FANCI_S3 PF14677.6 ORZ02314.1 - 9.4e-14 51.6 0.5 3.7e-12 46.4 0.0 3.3 3 0 0 3 3 3 1 FANCI solenoid 3 MA3 PF02847.17 ORZ02314.1 - 0.45 10.5 4.4 1.4 8.9 0.0 3.5 4 0 0 4 4 4 0 MA3 domain CBS PF00571.28 ORZ02315.1 - 2.5e-30 104.7 7.4 1.3e-07 31.9 0.0 5.2 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 ORZ02315.1 - 1.4e-12 47.4 1.6 2.6e-12 46.5 0.4 2.1 2 0 0 2 2 2 1 PB1 domain GAF PF01590.26 ORZ02315.1 - 0.035 14.8 0.3 3.8 8.1 0.0 3.0 3 1 0 3 3 3 0 GAF domain Fcf1 PF04900.12 ORZ02316.1 - 1.9e-28 98.8 0.5 4.2e-28 97.7 0.5 1.6 1 0 0 1 1 1 1 Fcf1 SWIRM-assoc_2 PF16496.5 ORZ02316.1 - 0.65 8.8 15.5 0.95 8.3 15.5 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4551 PF15087.6 ORZ02316.1 - 2.7 6.7 8.2 1.7 7.4 6.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.13 ORZ02316.1 - 7 6.5 19.1 9.5 6.0 19.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Not3 PF04065.15 ORZ02317.1 - 4.9e-91 304.3 29.0 4.9e-91 304.3 29.0 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 ORZ02317.1 - 1.1e-46 158.2 12.2 1.1e-46 158.2 12.2 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DHO_dh PF01180.21 ORZ02317.1 - 0.062 12.5 1.6 0.099 11.8 1.6 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase SesA PF17107.5 ORZ02317.1 - 1.3 9.3 8.0 0.35 11.1 0.9 2.7 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Syntaxin_2 PF14523.6 ORZ02317.1 - 7.2 7.0 16.4 0.07 13.5 5.9 2.7 1 1 1 2 2 2 0 Syntaxin-like protein GTP_EFTU PF00009.27 ORZ02318.1 - 4.1e-44 150.5 0.0 5.6e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORZ02318.1 - 1.1e-34 119.1 0.2 4.7e-34 117.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORZ02318.1 - 1.4e-10 41.4 0.1 3.5e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORZ02318.1 - 0.0066 16.5 0.1 0.062 13.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase LPD34 PF18852.1 ORZ02318.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Ras PF00071.22 ORZ02319.1 - 4.2e-55 185.8 0.0 5e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ02319.1 - 1.1e-32 112.8 0.0 1.8e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ02319.1 - 1.4e-14 54.0 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORZ02319.1 - 2.6e-05 23.7 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORZ02319.1 - 0.0003 20.4 0.1 0.0044 16.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 ORZ02319.1 - 0.00055 19.5 0.1 0.0012 18.4 0.0 1.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 ORZ02319.1 - 0.00092 19.3 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORZ02319.1 - 0.0017 18.2 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORZ02319.1 - 0.0019 18.6 0.0 0.0039 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORZ02319.1 - 0.0049 16.3 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 ORZ02319.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 ORZ02319.1 - 0.021 15.1 0.1 0.11 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 ORZ02319.1 - 0.029 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 ORZ02319.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 ORZ02319.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ORZ02319.1 - 0.044 12.9 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORZ02319.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORZ02319.1 - 0.053 14.0 0.1 0.085 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter ATPase PF06745.13 ORZ02319.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 KaiC MCM PF00493.23 ORZ02319.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DAP3 PF10236.9 ORZ02319.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Oxidored_FMN PF00724.20 ORZ02320.1 - 2.2e-96 323.1 0.0 2.5e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_2 PF12796.7 ORZ02321.1 - 3.2e-10 40.4 0.1 7.9e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 ORZ02321.1 - 2.8e-09 36.9 0.1 6.2e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.30 ORZ02321.1 - 4.2e-08 33.3 1.1 4.4e-06 26.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORZ02321.1 - 1.9e-07 30.8 0.8 0.0013 19.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORZ02321.1 - 1.8e-05 25.2 2.5 0.0017 18.9 0.6 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORZ02321.1 - 1.8e-05 24.9 0.6 6.7e-05 23.1 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Homeodomain PF00046.29 ORZ02322.1 - 1.4e-13 50.5 2.6 2.2e-13 49.8 2.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORZ02322.1 - 0.00024 20.9 0.1 0.00051 19.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Acyltransferase PF01553.21 ORZ02324.1 - 7.2e-09 35.4 0.0 3.1e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase B12D PF06522.11 ORZ02325.1 - 3.2e-18 65.3 0.0 4.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Glyco_hydro_65m PF03632.15 ORZ02325.1 - 0.031 13.1 0.1 0.039 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Anp1 PF03452.14 ORZ02326.1 - 8.8e-70 235.1 0.1 1e-69 234.9 0.1 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 ORZ02326.1 - 3.2e-06 27.0 0.1 0.0003 20.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 ORZ02326.1 - 0.059 13.9 2.5 0.15 12.6 2.5 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 MIT PF04212.18 ORZ02326.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF3219 PF11514.8 ORZ02326.1 - 0.097 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) Vir_act_alpha_C PF10400.9 ORZ02326.1 - 0.1 13.3 0.6 0.2 12.4 0.6 1.3 1 0 0 1 1 1 0 Virulence activator alpha C-term SgrT PF15894.5 ORZ02326.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT Glyoxalase_4 PF13669.6 ORZ02326.1 - 0.16 12.2 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Anp1 PF03452.14 ORZ02327.1 - 3.2e-10 39.9 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Anp1 NAD_Gly3P_dh_N PF01210.23 ORZ02328.1 - 2.2e-52 177.2 0.6 4.6e-52 176.2 0.3 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORZ02328.1 - 3.6e-49 166.7 0.4 7.5e-49 165.7 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 ORZ02328.1 - 0.014 16.0 0.5 0.34 11.5 0.5 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORZ02328.1 - 0.04 14.0 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase E1-E2_ATPase PF00122.20 ORZ02329.1 - 7.5e-52 175.5 4.3 6.3e-50 169.2 0.6 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORZ02329.1 - 7.5e-47 159.4 7.9 7.5e-47 159.4 7.9 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORZ02329.1 - 5.7e-24 84.0 0.0 1.1e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORZ02329.1 - 1.8e-21 77.4 0.5 1.3e-20 74.6 0.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ02329.1 - 1.2e-20 72.9 1.3 2.2e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ02329.1 - 1.3e-07 31.6 0.8 5.4e-06 26.3 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORZ02329.1 - 3.9e-06 27.4 0.0 1.2e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MCM PF00493.23 ORZ02330.1 - 2.3e-103 344.1 0.1 6.5e-103 342.6 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 ORZ02330.1 - 1.2e-35 122.1 0.0 2.5e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORZ02330.1 - 6.5e-28 97.0 1.3 1.5e-27 95.9 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORZ02330.1 - 3.5e-15 56.5 0.2 7.9e-15 55.3 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORZ02330.1 - 2.5e-06 27.0 0.0 0.00062 19.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORZ02330.1 - 2.6e-05 24.2 0.0 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORZ02330.1 - 6.3e-05 22.9 0.0 0.00078 19.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORZ02330.1 - 0.036 13.8 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain EMP70 PF02990.16 ORZ02332.1 - 6.1e-197 655.4 13.7 7.4e-197 655.1 13.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Aconitase PF00330.20 ORZ02335.1 - 4.7e-166 553.3 0.1 5.8e-166 553.1 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORZ02335.1 - 2.6e-39 134.5 0.0 6.4e-39 133.3 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain EI24 PF07264.11 ORZ02336.1 - 5.7e-13 49.5 0.1 7.4e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) MFS_1 PF07690.16 ORZ02337.1 - 3.2e-26 92.1 29.7 4.4e-26 91.6 29.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF350 PF03994.14 ORZ02337.1 - 0.022 14.9 0.1 0.022 14.9 0.1 2.8 3 1 0 3 3 3 0 Domain of Unknown Function (DUF350) PRONE PF03759.13 ORZ02337.1 - 0.26 10.1 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Ferrochelatase PF00762.19 ORZ02338.1 - 1.7e-114 382.2 0.0 1.9e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF4187 PF13821.6 ORZ02339.1 - 1.8e-23 82.1 2.4 4.2e-23 80.9 2.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 ORZ02339.1 - 7.1e-12 45.0 9.4 1.2e-11 44.3 9.4 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORZ02339.1 - 8.1e-06 25.8 4.3 8.1e-06 25.8 4.3 2.6 3 0 0 3 3 3 1 G-patch domain GP67 PF17634.2 ORZ02339.1 - 0.56 10.7 7.0 0.74 10.3 5.4 2.1 1 1 0 1 1 1 0 Gene product 67 YjfB_motility PF14070.6 ORZ02339.1 - 0.84 9.8 6.0 0.58 10.3 0.5 2.3 2 0 0 2 2 2 0 Putative motility protein Chitin_synth_1 PF01644.17 ORZ02340.1 - 1.9e-77 258.8 0.0 2.9e-77 258.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORZ02340.1 - 1.1e-32 111.8 0.2 4.1e-32 109.9 0.2 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORZ02340.1 - 4.3e-22 78.4 4.3 2e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORZ02340.1 - 0.00021 21.2 11.8 0.0024 17.8 11.8 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF5345 PF17280.2 ORZ02340.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) RasGEF PF00617.19 ORZ02341.1 - 1.4e-56 191.5 0.3 4.8e-56 189.8 0.3 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORZ02341.1 - 2.3e-20 72.8 0.5 2.3e-20 72.8 0.5 2.8 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_2 PF07653.17 ORZ02341.1 - 2.6e-10 39.8 0.0 5.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORZ02341.1 - 9.3e-09 35.0 0.1 2e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORZ02341.1 - 1.3e-08 34.2 0.2 4e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 SH3 domain TFIIA PF03153.13 ORZ02342.1 - 0.07 13.1 13.1 0.084 12.9 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORZ02342.1 - 0.73 9.4 9.1 1.2 8.7 9.1 1.4 1 0 0 1 1 1 0 Spt20 family SKG6 PF08693.10 ORZ02343.1 - 2.8e-06 26.6 0.2 5.7e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1180 PF06679.12 ORZ02343.1 - 0.0028 18.1 0.1 0.0028 18.1 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) m04gp34like PF12216.8 ORZ02343.1 - 0.0058 16.2 0.1 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 Immune evasion protein Orf78 PF06024.12 ORZ02343.1 - 0.01 16.1 0.2 0.031 14.6 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) DUF3365 PF11845.8 ORZ02343.1 - 0.03 14.6 0.6 0.047 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF4448 PF14610.6 ORZ02343.1 - 0.048 13.4 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 ORZ02343.1 - 0.089 12.7 2.1 0.12 12.2 0.0 2.0 1 1 1 2 2 2 0 TMEM154 protein family Pox_A14 PF05767.12 ORZ02343.1 - 0.097 12.8 0.2 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 RIFIN PF02009.16 ORZ02343.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rifin Miga PF10265.9 ORZ02343.1 - 0.11 11.4 4.6 0.16 10.9 4.6 1.2 1 0 0 1 1 1 0 Mitoguardin Insulin_TMD PF17870.1 ORZ02343.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Dickkopf_N PF04706.12 ORZ02343.1 - 0.3 11.6 10.5 0.72 10.4 10.5 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region 7TM_GPCR_Srh PF10318.9 ORZ02343.1 - 0.59 9.1 4.1 0.15 11.1 1.0 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh Plasmodium_Vir PF05795.11 ORZ02343.1 - 1.1 8.6 5.4 0.22 10.9 0.2 1.9 1 1 1 2 2 2 0 Plasmodium vivax Vir protein Fig1 PF12351.8 ORZ02343.1 - 1.6 8.6 6.5 0.21 11.5 1.7 1.9 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4834 PF16118.5 ORZ02343.1 - 1.7 9.7 3.0 8.7 7.4 3.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ASFV_J13L PF05568.11 ORZ02343.1 - 2.6 7.7 7.8 0.16 11.7 1.9 1.9 2 1 0 2 2 2 0 African swine fever virus J13L protein EB PF01683.18 ORZ02343.1 - 5.7 7.3 18.8 0.077 13.3 11.0 1.9 2 0 0 2 2 2 0 EB module Ras PF00071.22 ORZ02344.1 - 2e-55 186.8 0.0 2.3e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ02344.1 - 3.1e-22 79.0 0.0 4.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ02344.1 - 7.2e-09 35.3 0.0 9.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORZ02344.1 - 0.0004 20.0 0.0 0.0017 17.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain UMPH-1 PF05822.12 ORZ02345.1 - 2.7e-56 190.8 0.1 3e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 ORZ02345.1 - 7.6e-05 23.2 0.0 0.00011 22.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3818 PF12825.7 ORZ02346.1 - 6.9e-97 324.5 3.0 1.1e-96 323.8 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORZ02346.1 - 3.2e-16 59.5 0.5 1.9e-15 57.0 0.4 2.4 2 1 0 2 2 2 1 PX-associated PX PF00787.24 ORZ02346.1 - 9.6e-09 35.2 0.7 3.3e-08 33.5 0.7 1.9 1 0 0 1 1 1 1 PX domain Podoplanin PF05808.11 ORZ02347.1 - 8.4e-06 26.0 11.1 8.4e-06 26.0 11.1 2.0 1 1 1 2 2 2 1 Podoplanin Ndc1_Nup PF09531.10 ORZ02347.1 - 0.0033 16.2 11.2 0.0039 15.9 11.2 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Utp14 PF04615.13 ORZ02347.1 - 0.0095 14.6 22.3 0.011 14.3 22.3 1.1 1 0 0 1 1 1 1 Utp14 protein Yip1 PF04893.17 ORZ02347.1 - 0.025 14.3 0.0 0.065 13.0 0.0 1.6 2 0 0 2 2 2 0 Yip1 domain LAP1C PF05609.12 ORZ02347.1 - 0.027 13.6 18.5 0.038 13.1 18.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 ORZ02347.1 - 0.078 11.6 14.9 0.085 11.5 14.9 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 ORZ02347.1 - 0.27 9.8 24.1 0.33 9.5 24.1 1.1 1 0 0 1 1 1 0 Macoilin family SWIRM-assoc_2 PF16496.5 ORZ02347.1 - 5 5.9 32.1 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal PepSY_TM PF03929.16 ORZ02347.1 - 6.2 6.4 5.2 21 4.7 5.3 2.0 1 1 0 1 1 1 0 PepSY-associated TM region DUF2407_C PF13373.6 ORZ02347.1 - 7.4 6.7 12.8 54 4.0 12.8 2.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain Mitofilin PF09731.9 ORZ02347.1 - 9.1 5.0 16.6 12 4.6 16.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Kelch_5 PF13854.6 ORZ02348.1 - 1e-14 54.1 10.5 0.0001 22.2 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 ORZ02348.1 - 1.8e-10 40.9 12.7 1.3e-06 28.6 0.6 5.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORZ02348.1 - 2.8e-10 40.1 10.8 0.013 15.8 0.2 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 ORZ02348.1 - 6.3e-08 32.5 7.2 0.0008 19.4 0.4 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 ORZ02348.1 - 7.6e-06 25.7 6.2 0.71 9.9 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 ORZ02348.1 - 2.6e-05 23.7 10.7 0.029 14.0 0.1 4.6 4 1 0 4 4 4 2 Kelch motif Herpes_gE PF02480.16 ORZ02348.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2075 PF09848.9 ORZ02348.1 - 0.093 12.0 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CcmD PF04995.14 ORZ02348.1 - 0.71 10.0 4.2 0.26 11.4 1.2 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ThrE PF06738.12 ORZ02350.1 - 8.4e-50 169.4 20.7 1.1e-42 146.1 6.1 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORZ02350.1 - 2.8e-08 34.0 26.5 4.6e-08 33.3 7.8 2.6 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF4225 PF13988.6 ORZ02350.1 - 0.12 11.9 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Asp PF00026.23 ORZ02352.1 - 1.8e-59 201.7 0.1 5e-59 200.3 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORZ02352.1 - 1.7e-08 34.9 1.0 8.4e-06 26.1 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORZ02352.1 - 1.6e-06 28.0 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORZ02352.1 - 5e-06 27.1 0.0 0.0049 17.5 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 ORZ02352.1 - 0.026 15.1 0.0 13 6.4 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease NAD_kinase PF01513.21 ORZ02353.1 - 4.4e-60 203.4 0.0 6.4e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Sugar_tr PF00083.24 ORZ02354.1 - 1.6e-115 386.6 21.4 1.9e-115 386.3 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ02354.1 - 3.3e-23 82.2 35.2 3e-17 62.6 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 ORZ02354.1 - 0.15 12.3 0.2 0.15 12.3 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) SecG PF03840.14 ORZ02354.1 - 8.2 6.6 16.3 17 5.6 0.2 4.7 5 0 0 5 5 5 0 Preprotein translocase SecG subunit RhoGAP PF00620.27 ORZ02355.1 - 5.5e-35 120.4 0.0 1.2e-34 119.4 0.0 1.5 2 0 0 2 2 2 1 RhoGAP domain TilS PF09179.11 ORZ02355.1 - 0.076 13.5 0.0 7.2 7.2 0.0 2.7 2 0 0 2 2 2 0 TilS substrate binding domain Sedlin_N PF04628.13 ORZ02356.1 - 7.5e-28 97.3 0.2 9e-28 97.0 0.2 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ORZ02356.1 - 0.0054 16.7 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Metallophos PF00149.28 ORZ02357.1 - 1.5e-33 117.0 0.1 2e-33 116.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORZ02357.1 - 0.18 12.2 0.1 0.41 11.1 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain HCV_NS5a PF01506.19 ORZ02357.1 - 0.84 9.6 3.7 1.9 8.5 3.7 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor Ras PF00071.22 ORZ02358.1 - 1.9e-53 180.4 0.0 2.1e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ02358.1 - 2.4e-19 69.7 0.0 3.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ02358.1 - 8.3e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORZ02358.1 - 0.2 11.2 0.1 2.7 7.5 0.0 2.6 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ERCC3_RAD25_C PF16203.5 ORZ02359.1 - 3.9e-126 419.3 1.0 7.2e-126 418.4 1.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 ORZ02359.1 - 2.6e-39 134.3 0.0 7.9e-39 132.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ02359.1 - 4.4e-16 59.4 0.0 9.1e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORZ02359.1 - 6.6e-11 42.5 0.1 2e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ORZ02359.1 - 1.2e-08 34.1 0.0 1.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 ORZ02359.1 - 0.00014 21.7 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Securin PF04856.13 ORZ02360.1 - 0.14 12.1 9.7 0.035 14.1 1.8 2.2 2 0 0 2 2 2 0 Securin sister-chromatid separation inhibitor Gti1_Pac2 PF09729.9 ORZ02361.1 - 2.3e-58 197.3 0.0 5e-58 196.2 0.0 1.5 1 1 0 1 1 1 1 Gti1/Pac2 family Statherin PF03875.13 ORZ02361.1 - 0.051 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Statherin MFS_1 PF07690.16 ORZ02362.1 - 5.1e-30 104.6 41.3 2.2e-19 69.6 25.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ02362.1 - 7.9e-08 31.6 9.9 7.9e-08 31.6 9.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORZ02362.1 - 2.9e-07 29.3 24.2 7e-07 28.0 24.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 ORZ02362.1 - 3.8e-06 25.7 6.9 3.8e-06 25.7 6.9 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein Sec20 PF03908.13 ORZ02362.1 - 1.9 8.5 4.5 34 4.4 0.0 3.6 4 0 0 4 4 4 0 Sec20 Ras PF00071.22 ORZ02363.1 - 1.4e-58 197.0 0.3 1.7e-58 196.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ02363.1 - 3.2e-33 114.5 0.1 5e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ02363.1 - 1.4e-14 54.0 0.1 1.9e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORZ02363.1 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORZ02363.1 - 9.5e-06 25.1 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORZ02363.1 - 2.2e-05 24.1 0.1 5.6e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORZ02363.1 - 5.9e-05 23.0 0.2 0.0017 18.3 0.0 2.5 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 ORZ02363.1 - 0.00027 20.4 0.2 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 ORZ02363.1 - 0.0028 17.4 0.2 0.0052 16.5 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ02363.1 - 0.02 15.3 0.1 0.052 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORZ02363.1 - 0.023 14.5 0.3 0.023 14.5 0.3 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ORZ02363.1 - 0.025 14.9 0.0 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 ORZ02363.1 - 0.042 13.4 0.2 0.36 10.3 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 ORZ02363.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 ORZ02363.1 - 0.081 13.4 0.4 0.13 12.8 0.4 1.7 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 ORZ02363.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DAO PF01266.24 ORZ02364.1 - 1.4e-42 146.6 0.0 1.6e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORZ02364.1 - 9e-08 31.6 0.1 1.5e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORZ02364.1 - 3.3e-05 24.0 0.0 8.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORZ02364.1 - 9.2e-05 21.7 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORZ02364.1 - 0.0028 16.9 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORZ02364.1 - 0.0036 16.4 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORZ02364.1 - 0.089 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Mqo PF06039.15 ORZ02364.1 - 0.098 11.2 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 ORZ02364.1 - 0.11 13.1 0.1 0.48 11.0 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MtrD PF04207.12 ORZ02364.1 - 0.11 12.2 0.1 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D DUF1287 PF06940.11 ORZ02364.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Pyr_redox_3 PF13738.6 ORZ02364.1 - 0.19 11.0 0.1 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PPR_2 PF13041.6 ORZ02365.1 - 1.2e-06 28.5 0.3 0.0042 17.2 0.0 3.7 2 1 3 5 5 5 2 PPR repeat family PPR_3 PF13812.6 ORZ02365.1 - 0.00014 21.9 0.0 0.086 12.9 0.0 2.5 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 ORZ02365.1 - 0.0002 21.4 0.1 2.1 8.8 0.0 4.5 5 0 0 5 5 5 1 PPR repeat ECSIT PF06239.11 ORZ02365.1 - 0.0044 16.2 0.1 0.92 8.6 0.0 2.3 2 0 0 2 2 2 2 Evolutionarily conserved signalling intermediate in Toll pathway GSIII_N PF12437.8 ORZ02366.1 - 1.4e-67 226.4 0.1 2.5e-67 225.5 0.1 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 ORZ02366.1 - 2.9e-40 136.8 0.2 7.1e-40 135.6 0.2 1.7 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORZ02366.1 - 3.1e-20 72.5 0.0 5.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain BioT2 PF15368.6 ORZ02366.1 - 0.02 14.9 0.4 0.11 12.5 0.1 2.3 3 0 0 3 3 3 0 Spermatogenesis family BioT2 Latarcin PF10279.9 ORZ02366.1 - 0.083 13.3 0.0 0.69 10.4 0.5 2.3 2 1 0 2 2 2 0 Latarcin precursor Methyltransf_28 PF02636.17 ORZ02367.1 - 1.3e-64 218.4 0.1 1e-42 146.6 0.0 2.1 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase CAP_N PF01213.19 ORZ02368.1 - 4.5e-113 377.9 1.8 6.2e-113 377.5 1.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 ORZ02368.1 - 1.2e-62 210.2 6.2 2e-62 209.5 6.2 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 ORZ02368.1 - 0.00033 20.4 5.2 0.00076 19.2 5.2 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C PAR1 PF06521.11 ORZ02368.1 - 1.1 8.8 5.0 0.23 11.1 0.9 1.9 2 0 0 2 2 2 0 PAR1 protein PRIMA1 PF16101.5 ORZ02368.1 - 1.2 9.2 16.4 8.3 6.5 8.1 3.4 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 MFS_1 PF07690.16 ORZ02369.1 - 5.3e-41 140.7 28.0 1e-40 139.8 27.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily SoxE PF06525.11 ORZ02369.1 - 0.049 13.1 0.4 0.091 12.2 0.4 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain BRAP2 PF07576.12 ORZ02370.1 - 5.7e-20 71.4 0.2 1.2e-19 70.4 0.2 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 ORZ02370.1 - 4.6e-14 52.5 5.6 4.6e-14 52.5 5.6 2.8 3 0 0 3 3 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 ORZ02370.1 - 6.2e-08 32.8 11.6 6.2e-08 32.8 11.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ORZ02370.1 - 1.6e-06 28.0 7.6 1.6e-06 28.0 7.6 3.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORZ02370.1 - 2e-06 27.5 12.0 2e-06 27.5 12.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORZ02370.1 - 5.5e-06 26.1 16.1 0.00018 21.3 6.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ02370.1 - 1.7e-05 24.6 9.9 1.7e-05 24.6 9.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORZ02370.1 - 8.8e-05 22.2 8.6 8.8e-05 22.2 8.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 ORZ02370.1 - 0.00065 19.9 10.9 0.00065 19.9 10.9 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORZ02370.1 - 0.0027 17.7 8.0 0.0069 16.4 8.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORZ02370.1 - 0.0046 16.9 8.4 0.0046 16.9 8.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain YabA PF06156.13 ORZ02370.1 - 0.0098 16.5 4.1 0.0098 16.5 4.1 2.4 3 0 0 3 3 2 1 Initiation control protein YabA zf-C3HC4_4 PF15227.6 ORZ02370.1 - 0.028 14.6 14.4 0.071 13.3 7.5 3.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Rootletin PF15035.6 ORZ02370.1 - 1.5 8.8 20.8 1.9 8.5 5.2 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Pro_CA PF00484.19 ORZ02370.1 - 1.8 8.9 4.4 0.64 10.3 0.1 2.1 2 0 0 2 2 2 0 Carbonic anhydrase Prok-RING_4 PF14447.6 ORZ02370.1 - 2.8 7.9 25.8 1 9.3 8.9 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 FUSC PF04632.12 ORZ02370.1 - 9.8 4.6 9.4 13 4.1 9.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Dam1 PF08653.10 ORZ02370.1 - 10 6.0 6.8 27 4.7 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 DHHC PF01529.20 ORZ02372.1 - 6.6e-33 113.7 19.3 3.1e-32 111.5 14.7 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF35_N PF12172.8 ORZ02372.1 - 0.036 14.0 4.7 0.079 12.9 4.7 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2070 PF09843.9 ORZ02372.1 - 1.9 6.7 5.5 3.2 5.9 5.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GATA PF00320.27 ORZ02373.1 - 5.2e-16 58.0 6.3 1.2e-15 56.7 6.3 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORZ02373.1 - 5.6e-10 39.4 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORZ02373.1 - 3.7e-06 26.9 4.6 4.2e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 PAS fold Zn-ribbon_8 PF09723.10 ORZ02373.1 - 0.0014 18.7 0.1 0.0031 17.6 0.1 1.6 1 0 0 1 1 1 1 Zinc ribbon domain TFIIA PF03153.13 ORZ02373.1 - 0.0014 18.7 18.3 0.0014 18.7 18.3 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PAS_9 PF13426.7 ORZ02373.1 - 0.0058 16.9 0.0 0.02 15.1 0.0 2.0 1 1 1 2 2 2 1 PAS domain TF_Zn_Ribbon PF08271.12 ORZ02373.1 - 0.073 12.6 0.2 0.93 9.1 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Presenilin PF01080.17 ORZ02373.1 - 0.15 10.8 10.7 0.26 10.0 10.7 1.3 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 ORZ02373.1 - 0.57 10.0 12.3 1.6 8.6 3.4 2.3 2 0 0 2 2 2 0 Coilin N-terminus Macoilin PF09726.9 ORZ02373.1 - 0.67 8.4 10.3 0.96 7.9 10.3 1.2 1 0 0 1 1 1 0 Macoilin family DUF3408 PF11888.8 ORZ02373.1 - 1.5 9.0 16.1 1.3 9.2 8.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) ArfGap PF01412.18 ORZ02373.1 - 4.2 7.5 7.4 1.5 8.9 0.3 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Baculo_PP31 PF05311.11 ORZ02373.1 - 6.4 6.2 9.8 1.1 8.7 3.5 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) CTU2 PF10288.9 ORZ02373.1 - 7.5 6.8 14.3 7.9 6.8 1.3 2.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Thymidylat_synt PF00303.19 ORZ02375.1 - 4.1e-117 390.1 0.0 4.6e-117 389.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Ezh2_MCSS PF18600.1 ORZ02375.1 - 0.079 12.6 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 MCSS domain Ribosomal_S3_C PF00189.20 ORZ02376.1 - 2e-22 79.5 0.7 5.9e-22 78.0 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORZ02376.1 - 6.1e-13 48.4 0.1 1e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORZ02376.1 - 0.022 15.3 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Nmad5 PF18757.1 ORZ02377.1 - 0.0023 18.2 0.1 0.0027 18.0 0.1 1.1 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 Cpn60_TCP1 PF00118.24 ORZ02378.1 - 2.4e-168 560.8 3.3 2.7e-168 560.6 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AMP-binding PF00501.28 ORZ02379.1 - 4.9e-65 219.8 0.1 6.5e-65 219.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ02379.1 - 2e-05 25.5 0.7 2e-05 25.5 0.7 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Amidohydro_1 PF01979.20 ORZ02380.1 - 6.6e-21 75.0 0.0 3.8e-17 62.6 0.0 3.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ORZ02380.1 - 1.2e-19 71.2 2.0 3.6e-13 49.8 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family TPR_4 PF07721.14 ORZ02380.1 - 0.1 13.3 0.1 0.46 11.2 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L44 PF00935.19 ORZ02381.1 - 2.7e-38 130.3 9.8 3.9e-38 129.8 9.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 RPE65 PF03055.15 ORZ02382.1 - 3.2e-94 316.8 0.4 3.6e-94 316.6 0.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Ydc2-catalyt PF09159.10 ORZ02383.1 - 9.5e-23 81.3 5.4 5e-15 56.0 0.0 3.1 1 1 2 3 3 3 3 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 ORZ02383.1 - 4.8e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 SAP domain DnaJ_C PF01556.18 ORZ02385.1 - 5.7e-36 123.8 0.0 7.5e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORZ02385.1 - 3.9e-24 84.5 3.6 6.1e-24 83.9 3.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORZ02385.1 - 9.4e-16 57.9 16.7 1.6e-15 57.2 16.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORZ02385.1 - 5e-08 32.8 6.3 8.2e-05 22.5 0.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORZ02385.1 - 4e-05 23.6 6.7 0.033 14.2 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 ORZ02385.1 - 0.06 13.8 4.8 0.13 12.7 4.8 1.5 1 0 0 1 1 1 0 Cytochrome c3 TackOD1 PF18551.1 ORZ02385.1 - 0.089 12.5 6.9 0.53 9.9 0.5 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 ORZ02385.1 - 0.14 12.6 8.0 0.3 11.5 1.5 3.4 2 1 1 3 3 3 0 Restriction alleviation protein Lar Prok-RING_4 PF14447.6 ORZ02385.1 - 0.15 11.9 5.0 0.81 9.6 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 ORZ02385.1 - 0.27 11.3 9.5 0.86 9.7 9.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.13 ORZ02385.1 - 0.28 9.0 1.5 0.59 7.9 1.3 1.4 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C3HC4_3 PF13920.6 ORZ02385.1 - 0.36 10.7 8.0 2.9 7.8 1.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ02385.1 - 0.71 9.9 11.2 1.4 9.0 1.9 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Cytochrome_C7 PF14522.6 ORZ02385.1 - 2.9 7.9 11.2 2e+02 2.1 11.2 2.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-RING_10 PF16685.5 ORZ02385.1 - 3.3 7.9 5.9 1 9.5 0.5 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn-ribbon_8 PF09723.10 ORZ02385.1 - 6 7.1 17.7 31 4.8 0.9 4.0 2 2 1 3 3 3 0 Zinc ribbon domain UAA PF08449.11 ORZ02386.1 - 9e-08 31.7 13.0 1.6e-07 30.8 13.0 1.3 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 ORZ02386.1 - 6e-06 26.5 5.9 6e-06 26.5 5.9 2.4 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 ORZ02386.1 - 7e-05 22.3 0.2 7e-05 22.3 0.2 1.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UPF0121 PF03661.13 ORZ02386.1 - 0.013 14.9 2.5 0.024 14.0 2.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) Peptidase_C1_2 PF03051.15 ORZ02386.1 - 0.038 12.8 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Peptidase C1-like family Multi_Drug_Res PF00893.19 ORZ02386.1 - 0.41 11.3 10.4 7.5 7.3 0.3 3.2 2 1 0 2 2 2 0 Small Multidrug Resistance protein PHO4 PF01384.20 ORZ02386.1 - 0.42 9.6 11.4 0.22 10.5 2.6 2.4 1 1 0 2 2 2 0 Phosphate transporter family Zn_clus PF00172.18 ORZ02388.1 - 1.2e-10 41.3 10.9 1.7e-10 40.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-gamma PF00631.22 ORZ02390.1 - 1.3e-08 34.7 6.5 6.3 6.9 0.0 5.7 5 0 0 5 5 5 5 GGL domain FliX PF10768.9 ORZ02390.1 - 0.43 11.1 5.9 5.4 7.5 0.3 3.3 1 1 1 2 2 2 0 Class II flagellar assembly regulator PP2C_C PF07830.13 ORZ02390.1 - 1.9 9.0 3.7 20 5.7 0.7 3.0 1 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain UFC1 PF08694.11 ORZ02390.1 - 3.3 7.3 8.5 23 4.6 0.1 4.4 3 1 1 4 4 4 0 Ubiquitin-fold modifier-conjugating enzyme 1 DUF573 PF04504.14 ORZ02390.1 - 5 7.9 8.0 2.7 8.7 0.8 3.1 1 1 1 2 2 2 0 Protein of unknown function, DUF573 UPF0020 PF01170.18 ORZ02391.1 - 3.3e-10 40.0 0.0 7.7e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 ORZ02391.1 - 0.003 16.9 0.0 0.0095 15.2 0.0 1.7 1 1 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 ORZ02391.1 - 0.014 15.1 0.0 0.81 9.3 0.0 2.4 2 0 0 2 2 2 0 DNA methylase tRNA-synt_2 PF00152.20 ORZ02392.1 - 1.6e-100 336.2 0.0 2e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORZ02392.1 - 3.3e-07 30.2 0.0 6.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORZ02392.1 - 5.1e-05 22.9 0.6 0.00019 21.0 0.1 2.1 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 ORZ02392.1 - 0.033 14.1 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Prot_ATP_ID_OB PF16450.5 ORZ02392.1 - 0.098 12.6 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain cNMP_binding PF00027.29 ORZ02393.1 - 2.2e-32 111.0 0.0 2.7e-16 59.4 0.0 5.6 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 ORZ02393.1 - 1.5e-18 67.7 2.9 1.5e-18 67.7 2.9 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase SH3_16 PF18348.1 ORZ02393.1 - 0.039 13.7 0.0 7.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_1 PF00018.28 ORZ02394.1 - 5.3e-13 48.3 0.1 1e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORZ02394.1 - 1.7e-09 37.2 0.0 2.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORZ02394.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 ORZ02394.1 - 0.024 14.5 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_3 PF08239.11 ORZ02394.1 - 0.039 14.2 0.1 0.086 13.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain FA_desaturase PF00487.24 ORZ02395.1 - 1.9e-43 149.2 8.6 3.1e-43 148.4 8.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORZ02395.1 - 1.6e-18 66.6 0.1 3.8e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Caps_synth_CapC PF14102.6 ORZ02395.1 - 0.17 12.3 0.2 0.17 12.3 0.2 2.3 2 1 0 2 2 2 0 Capsule biosynthesis CapC PMT PF02366.18 ORZ02397.1 - 2.6e-87 292.5 17.8 2.6e-87 292.5 17.8 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORZ02397.1 - 2.6e-61 206.7 12.0 2.6e-61 206.7 12.0 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORZ02397.1 - 1.3e-25 90.4 0.7 2e-25 89.8 0.7 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 ORZ02397.1 - 0.00064 20.0 11.9 0.00064 20.0 11.9 2.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase FKBP_C PF00254.28 ORZ02398.1 - 4.5e-31 107.0 0.1 2.6e-30 104.6 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 ORZ02398.1 - 5.1e-27 94.5 0.0 5.1e-27 94.5 0.0 3.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain LAP1C PF05609.12 ORZ02398.1 - 7.8 5.5 26.3 12 4.9 26.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ras PF00071.22 ORZ02399.1 - 1e-58 197.5 0.1 1.3e-58 197.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ02399.1 - 1.2e-36 125.5 0.1 1.7e-36 125.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ02399.1 - 6.7e-15 55.0 0.1 8.7e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORZ02399.1 - 2.5e-05 23.8 0.0 3.6e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORZ02399.1 - 9.1e-05 22.5 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORZ02399.1 - 0.00023 20.7 0.1 0.0018 17.8 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORZ02399.1 - 0.00053 19.4 0.1 0.00069 19.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORZ02399.1 - 0.00083 19.3 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 ORZ02399.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CPSF73-100_C PF11718.8 ORZ02400.1 - 3.7e-58 196.6 2.4 3.7e-58 196.6 2.4 1.5 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 ORZ02400.1 - 6.3e-32 110.1 0.0 1.5e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 ORZ02400.1 - 1.9e-21 77.0 0.3 3.1e-21 76.3 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORZ02400.1 - 1.1e-19 70.7 0.0 3.9e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 ORZ02400.1 - 8.2e-15 54.5 0.1 2.2e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 ORZ02400.1 - 3.1e-08 33.7 0.0 9.9e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ORZ02400.1 - 4.4e-08 32.9 1.1 1.4e-07 31.2 0.1 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORZ02400.1 - 0.015 14.5 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative beta-lactamase-like family KxDL PF10241.9 ORZ02400.1 - 0.075 13.3 1.4 0.31 11.4 1.4 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein U5_2-snRNA_bdg PF10597.9 ORZ02400.1 - 0.11 12.5 0.4 8.8 6.4 0.0 2.6 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 Cu_amine_oxidN1 PF07833.11 ORZ02400.1 - 0.14 12.7 0.3 0.45 11.0 0.3 1.8 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain Ribosomal_L27e PF01777.18 ORZ02401.1 - 8.7e-38 128.6 9.1 8.7e-38 128.6 9.1 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 ORZ02401.1 - 0.00045 20.1 3.6 0.0011 18.8 3.6 1.8 1 1 0 1 1 1 1 KOW motif zf-C2H2_12 PF18658.1 ORZ02402.1 - 0.00052 19.5 2.6 0.92 9.1 0.1 3.2 2 1 1 3 3 3 2 Zinc-finger C2H2-type Rad50_zn_hook PF04423.14 ORZ02402.1 - 0.00067 19.4 0.5 0.63 9.9 0.0 2.3 2 0 0 2 2 2 2 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 ORZ02402.1 - 0.00083 19.4 5.9 0.11 12.6 2.8 3.3 2 1 0 2 2 2 1 Zinc ribbon domain zf-ribbon_3 PF13248.6 ORZ02402.1 - 0.0023 17.3 2.5 0.99 8.9 0.0 3.3 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.7 ORZ02402.1 - 0.016 15.2 6.8 0.18 11.9 4.8 2.8 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 ORZ02402.1 - 0.02 14.8 1.3 0.02 14.8 1.3 2.2 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-met PF12874.7 ORZ02402.1 - 0.031 14.7 1.3 0.58 10.6 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORZ02402.1 - 0.035 14.5 8.4 1.4 9.5 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-TFIIB PF13453.6 ORZ02402.1 - 0.037 13.3 3.7 3.4 7.1 0.2 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger Cys_rich_CPXG PF14255.6 ORZ02402.1 - 0.078 12.9 7.5 0.083 12.8 0.4 3.1 3 0 0 3 3 3 0 Cysteine-rich CPXCG Prok-RING_4 PF14447.6 ORZ02402.1 - 0.087 12.7 3.6 6.9 6.6 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.12 ORZ02402.1 - 0.13 12.2 6.9 4 7.5 6.7 2.8 1 1 1 2 2 2 0 zinc-ribbons zf-piccolo PF05715.13 ORZ02402.1 - 0.16 12.2 3.7 34 4.7 0.1 3.2 2 1 1 3 3 3 0 Piccolo Zn-finger zf-C2H2_4 PF13894.6 ORZ02402.1 - 0.18 12.7 8.9 1.9 9.6 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DNA_ligase_ZBD PF03119.16 ORZ02402.1 - 0.19 11.8 6.8 3 8.0 0.2 3.6 4 0 0 4 4 4 0 NAD-dependent DNA ligase C4 zinc finger domain PHD PF00628.29 ORZ02402.1 - 0.48 10.4 7.1 11 6.0 0.7 3.3 3 0 0 3 3 3 0 PHD-finger zf-HIT PF04438.16 ORZ02402.1 - 0.51 10.3 5.2 10 6.1 0.0 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-Di19 PF05605.12 ORZ02402.1 - 0.77 10.1 9.7 2 8.8 4.9 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.12 ORZ02402.1 - 2.3 7.8 6.6 9.9 5.8 0.0 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 ORZ02402.1 - 4.4 7.1 7.6 6.4 6.6 0.1 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Chs7 PF12271.8 ORZ02404.1 - 1.4e-108 362.6 18.3 1.7e-108 362.3 18.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone HAD_2 PF13419.6 ORZ02406.1 - 4e-30 105.2 0.0 4.8e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORZ02406.1 - 1.4e-13 51.6 0.0 4.5e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORZ02406.1 - 0.0021 18.1 0.0 0.76 9.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORZ02406.1 - 0.0046 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ORZ02406.1 - 0.011 16.2 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nucleotid_trans PF03407.16 ORZ02408.1 - 1.8e-21 77.1 0.3 2.7e-21 76.5 0.3 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Aldedh PF00171.22 ORZ02409.1 - 3.9e-135 450.9 0.2 4.3e-135 450.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORZ02409.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PDZ_5 PF17817.1 ORZ02410.1 - 0.054 13.8 0.2 0.076 13.3 0.2 1.3 1 0 0 1 1 1 0 PDZ domain MFA1_2 PF17317.2 ORZ02410.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 GCP_C_terminal PF04130.13 ORZ02411.1 - 3.1e-56 191.1 0.7 5.9e-56 190.2 0.7 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORZ02411.1 - 1.1e-24 87.7 0.0 2.6e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Sigma70_r4_2 PF08281.12 ORZ02411.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Isy1 PF06246.12 ORZ02412.1 - 0.02 14.4 0.3 0.036 13.6 0.3 1.4 1 0 0 1 1 1 0 Isy1-like splicing family Mg_trans_NIPA PF05653.14 ORZ02413.1 - 1.5e-66 224.5 4.0 3.7e-62 210.1 2.4 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORZ02413.1 - 4.5e-06 26.9 0.2 4.5e-06 26.9 0.2 4.1 3 1 2 5 5 5 1 EamA-like transporter family PUNUT PF16913.5 ORZ02413.1 - 0.0004 19.7 0.4 0.0004 19.7 0.4 2.7 2 1 0 3 3 3 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 ORZ02413.1 - 0.0031 16.5 5.0 0.23 10.4 0.2 2.4 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like GPR_Gpa2_C PF11970.8 ORZ02413.1 - 0.017 15.2 1.1 0.017 15.2 1.1 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1461 PF07314.11 ORZ02413.1 - 0.66 9.9 4.5 0.73 9.7 1.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) Ribosomal_L16 PF00252.18 ORZ02414.1 - 1.4e-45 154.5 0.1 1.7e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Velvet PF11754.8 ORZ02415.1 - 5e-29 102.0 0.1 6.7e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.8 ORZ02416.1 - 2.4e-11 44.0 4.8 2.9e-11 43.8 0.1 2.1 2 0 0 2 2 2 2 Velvet factor RRM_1 PF00076.22 ORZ02417.1 - 1.2e-38 130.8 0.4 5.7e-22 77.3 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORZ02417.1 - 2.4e-15 56.4 0.1 5.3e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORZ02417.1 - 0.0068 16.0 0.0 0.17 11.5 0.1 2.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 ORZ02417.1 - 0.12 12.3 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ALAD PF00490.21 ORZ02419.1 - 0.078 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase UQ_con PF00179.26 ORZ02420.1 - 9.3e-40 135.5 0.0 1.1e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORZ02420.1 - 0.00076 19.8 0.0 0.00094 19.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain COS PF18568.1 ORZ02420.1 - 0.026 14.5 0.2 0.042 13.8 0.2 1.3 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain ECH_1 PF00378.20 ORZ02421.1 - 6.7e-43 146.8 0.0 8.5e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORZ02421.1 - 6.2e-17 62.1 0.0 7.7e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CpxA_peri PF16527.5 ORZ02421.1 - 0.086 13.2 0.4 0.13 12.6 0.4 1.2 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain DUF3446 PF11928.8 ORZ02422.1 - 0.052 13.9 13.1 2.6 8.4 8.3 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain CFEM PF05730.11 ORZ02422.1 - 0.097 12.8 5.8 0.21 11.7 5.8 1.6 1 1 0 1 1 1 0 CFEM domain DUF4473 PF14747.6 ORZ02422.1 - 0.11 13.1 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Sporozoite_P67 PF05642.11 ORZ02422.1 - 0.51 8.4 4.5 0.49 8.4 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pyr_redox_2 PF07992.14 ORZ02423.1 - 4.5e-66 223.1 0.0 6.4e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORZ02423.1 - 9.3e-31 106.3 0.1 1.9e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORZ02423.1 - 2.4e-21 76.1 1.5 6.7e-19 68.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORZ02423.1 - 2.1e-16 60.1 1.6 5.7e-16 58.6 1.6 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORZ02423.1 - 5.2e-06 25.8 0.1 0.00043 19.5 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ORZ02423.1 - 4.6e-05 22.3 2.8 0.082 11.6 0.3 3.3 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 ORZ02423.1 - 7.5e-05 22.1 0.3 0.05 12.9 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ORZ02423.1 - 0.00013 21.4 0.0 0.00032 20.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORZ02423.1 - 0.00014 22.0 4.5 0.00038 20.6 3.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORZ02423.1 - 0.00093 18.9 10.8 0.027 14.1 2.0 3.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 ORZ02423.1 - 0.0014 18.1 0.4 0.0037 16.7 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORZ02423.1 - 0.002 18.1 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 ORZ02423.1 - 0.0069 15.7 0.2 0.015 14.6 0.2 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 ORZ02423.1 - 0.0077 15.4 1.1 0.39 9.7 0.5 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORZ02423.1 - 0.016 14.3 2.4 0.016 14.3 2.4 2.4 3 0 0 3 3 3 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ORZ02423.1 - 0.027 14.0 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORZ02423.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 ORZ02423.1 - 0.18 10.8 0.1 3.2 6.7 0.0 2.7 2 1 2 4 4 4 0 Lycopene cyclase protein DEAD PF00270.29 ORZ02424.1 - 5e-34 117.6 0.2 1.4e-33 116.2 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ02424.1 - 1.7e-27 95.9 0.1 1.5e-26 92.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ02424.1 - 1.9e-06 28.0 0.0 3.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORZ02424.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORZ02424.1 - 0.28 11.5 1.8 1.7 8.9 0.6 2.6 2 1 0 2 2 2 0 AAA domain Nefa_Nip30_N PF10187.9 ORZ02425.1 - 1.5e-19 70.3 9.1 1.5e-19 70.3 9.1 2.6 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 ORZ02425.1 - 0.00035 20.3 20.5 0.00046 19.9 20.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Dict-STAT-coil PF09267.10 ORZ02425.1 - 0.0096 16.3 2.2 0.016 15.6 2.2 1.3 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil HsdM_N PF12161.8 ORZ02425.1 - 0.05 14.2 0.9 4.5 7.9 0.4 2.2 2 0 0 2 2 2 0 HsdM N-terminal domain PBP3 PF18056.1 ORZ02425.1 - 0.83 9.8 5.1 1.8 8.7 5.1 1.5 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain FSA_C PF10479.9 ORZ02425.1 - 0.99 7.5 6.5 1.2 7.2 6.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_UL74 PF07982.12 ORZ02425.1 - 1.5 7.7 8.1 2.2 7.2 8.1 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Borrelia_orfA PF02414.15 ORZ02425.1 - 1.6 8.3 6.8 0.16 11.6 1.1 1.8 2 0 0 2 2 2 0 Borrelia ORF-A DUF1077 PF06417.12 ORZ02426.1 - 2.3e-48 163.1 3.0 3e-48 162.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) HAD_2 PF13419.6 ORZ02428.1 - 7.1e-20 71.8 0.0 8.7e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORZ02428.1 - 2.4e-12 47.6 0.0 2.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORZ02428.1 - 6.4e-09 35.8 0.1 1e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_56 PF01630.18 ORZ02428.1 - 0.068 12.2 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Hyaluronidase Sds3 PF08598.11 ORZ02429.1 - 9e-20 71.6 16.6 9e-20 71.6 16.6 3.5 2 2 0 2 2 2 1 Sds3-like RICH PF05062.12 ORZ02429.1 - 0.27 11.6 5.4 0.89 9.9 0.3 2.7 2 0 0 2 2 2 0 RICH domain LRR_4 PF12799.7 ORZ02430.1 - 3.8e-30 103.4 33.5 6.1e-07 29.7 2.1 6.7 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORZ02430.1 - 1.6e-17 63.0 32.7 1.8e-05 24.4 5.0 6.5 3 2 4 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 ORZ02430.1 - 6.8e-16 58.2 19.9 2.6e-08 33.6 3.7 3.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 ORZ02430.1 - 0.019 15.4 26.8 3.7 8.5 0.1 8.9 9 2 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 ORZ02430.1 - 0.039 14.0 21.6 0.65 10.2 0.5 7.6 10 0 0 10 10 10 0 Leucine Rich repeat UB2H PF14814.6 ORZ02430.1 - 0.67 10.0 3.1 54 3.9 0.0 4.3 4 2 1 5 5 5 0 Bifunctional transglycosylase second domain WD40 PF00400.32 ORZ02431.1 - 2.6e-60 198.9 14.0 2.9e-09 37.4 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORZ02431.1 - 5.4e-24 84.3 13.8 7.7e-24 83.8 13.8 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORZ02431.1 - 9.7e-21 73.9 0.0 5.9e-05 23.3 0.0 6.1 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ02431.1 - 9.7e-11 41.5 0.0 0.003 17.0 0.0 4.7 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 ORZ02431.1 - 8.4e-09 34.8 0.1 0.3 10.0 0.0 5.1 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ORZ02431.1 - 3.4e-05 23.6 0.2 11 6.1 0.0 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 ORZ02431.1 - 6.4e-05 22.4 0.1 0.17 11.2 0.0 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 ORZ02431.1 - 6.8e-05 21.6 0.1 0.018 13.6 0.0 2.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain VID27 PF08553.10 ORZ02431.1 - 0.0042 16.2 0.0 0.27 10.2 0.0 3.0 3 0 0 3 3 3 1 VID27 C-terminal WD40-like domain DUF5122 PF17164.4 ORZ02431.1 - 0.016 15.5 2.2 49 4.3 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Ntox1 PF15500.6 ORZ02431.1 - 0.053 13.9 0.8 0.1 12.9 0.8 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Nup160 PF11715.8 ORZ02431.1 - 0.056 12.1 0.1 3.7 6.1 0.0 3.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 CCDC53 PF10152.9 ORZ02431.1 - 0.072 13.5 2.2 0.14 12.6 2.2 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex MMS1_N PF10433.9 ORZ02431.1 - 0.089 11.4 0.0 1.2 7.7 0.0 2.1 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF724 PF05266.14 ORZ02431.1 - 0.094 12.5 6.0 0.13 12.0 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nucleoporin_N PF08801.11 ORZ02431.1 - 0.14 10.9 0.4 15 4.2 0.2 3.4 1 1 0 1 1 1 0 Nup133 N terminal like MSA-2c PF12238.8 ORZ02431.1 - 0.21 11.5 4.5 0.43 10.6 4.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c SKA1 PF07160.12 ORZ02431.1 - 0.22 11.4 3.9 0.32 10.8 3.9 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Proteasome_A_N PF10584.9 ORZ02431.1 - 0.22 11.2 1.2 93 2.8 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Spc7 PF08317.11 ORZ02431.1 - 0.43 9.4 7.1 0.62 8.9 7.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Myb_DNA-bind_3 PF12776.7 ORZ02431.1 - 0.46 11.5 2.2 0.87 10.6 2.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PEARLI-4 PF05278.12 ORZ02431.1 - 1.7 8.2 6.1 2.4 7.7 6.1 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Phage_Mu_Gam PF07352.12 ORZ02431.1 - 3.8 7.4 7.8 1.8 8.4 4.4 1.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein TMPIT PF07851.13 ORZ02431.1 - 7.2 5.8 6.2 10 5.3 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein COX6A PF02046.15 ORZ02432.1 - 1.9e-30 105.6 0.8 2.3e-30 105.4 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa EccE PF11203.8 ORZ02432.1 - 0.019 15.3 0.1 0.029 14.7 0.1 1.2 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Solute_trans_a PF03619.16 ORZ02434.1 - 1.4e-91 306.7 13.4 1.8e-91 306.4 13.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ECF_trnsprt PF12822.7 ORZ02434.1 - 9.9 6.2 15.9 9.1 6.3 5.6 2.2 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Cyt-b5 PF00173.28 ORZ02435.1 - 7.3e-27 93.3 0.0 9.4e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PUNUT PF16913.5 ORZ02436.1 - 1.3e-05 24.6 0.6 1.3e-05 24.6 0.6 2.1 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 ORZ02436.1 - 1.6e-05 24.2 0.6 1.6e-05 24.2 0.6 2.2 2 1 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 ORZ02436.1 - 1.8e-05 24.9 29.7 0.0027 17.9 5.3 3.2 3 0 0 3 3 3 3 EamA-like transporter family TPT PF03151.16 ORZ02436.1 - 0.001 18.5 1.3 0.001 18.5 1.3 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family Mit_proteolip PF08039.11 ORZ02436.1 - 0.0085 16.5 0.1 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial proteolipid Kelch_4 PF13418.6 ORZ02437.1 - 1.6e-10 40.8 13.2 1e-05 25.4 0.1 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORZ02437.1 - 3e-10 39.9 13.4 0.0044 17.0 0.4 5.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ORZ02437.1 - 7.9e-08 32.4 1.5 0.029 14.7 0.0 4.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORZ02437.1 - 2.4e-05 24.5 12.3 2.7 8.4 0.1 5.1 4 1 1 5 5 5 4 Kelch motif CYYR1 PF10873.8 ORZ02437.1 - 8.4e-05 23.1 0.2 0.00015 22.2 0.2 1.4 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Kelch_2 PF07646.15 ORZ02437.1 - 0.00022 21.0 2.7 6.5 6.9 0.0 5.3 5 0 0 5 5 5 1 Kelch motif VSP PF03302.13 ORZ02437.1 - 0.0027 16.6 0.9 0.0039 16.1 0.9 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 ORZ02437.1 - 0.0056 16.1 7.3 0.01 15.2 7.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.25 ORZ02437.1 - 0.0099 15.4 0.6 5.6 6.6 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Podoplanin PF05808.11 ORZ02437.1 - 0.011 15.9 2.2 0.022 14.9 2.2 1.5 1 0 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.15 ORZ02437.1 - 0.049 13.4 3.2 0.13 12.0 3.2 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PARM PF17061.5 ORZ02437.1 - 0.091 12.9 0.8 0.16 12.1 0.8 1.3 1 0 0 1 1 1 0 PARM DUF2613 PF11021.8 ORZ02437.1 - 4.7 7.4 9.9 12 6.1 9.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) RRM_1 PF00076.22 ORZ02438.1 - 5.9e-09 35.6 0.0 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ02438.1 - 0.011 15.9 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif HMG_box PF00505.19 ORZ02439.1 - 1e-19 70.7 1.5 1.2e-19 70.5 1.5 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ02439.1 - 2.6e-11 43.9 0.6 2.9e-11 43.8 0.6 1.1 1 0 0 1 1 1 1 HMG-box domain PhosphMutase PF10143.9 ORZ02440.1 - 1.4e-50 171.5 0.0 1.9e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 ORZ02440.1 - 7.2e-27 94.3 0.0 9e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 ORZ02440.1 - 0.00023 20.9 0.4 0.001 18.7 0.2 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORZ02440.1 - 0.1 11.9 0.1 0.33 10.3 0.1 1.7 2 0 0 2 2 2 0 Sulfatase Cmc1 PF08583.10 ORZ02441.1 - 2.5e-13 49.8 8.5 3.7e-13 49.3 8.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 ORZ02441.1 - 0.029 14.5 4.9 0.038 14.1 1.5 2.4 1 1 1 2 2 2 0 CHCH domain Ndufs5 PF10200.9 ORZ02441.1 - 0.35 11.2 3.8 0.92 9.8 3.8 1.8 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pribosyltran PF00156.27 ORZ02442.1 - 1.1e-23 83.5 0.0 1.4e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ORZ02442.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 ORZ02442.1 - 0.014 14.8 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase 3-HAO PF06052.12 ORZ02443.1 - 2.1e-64 215.7 0.2 2.3e-64 215.6 0.2 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 ORZ02443.1 - 1.3e-06 28.0 0.2 2.5e-06 27.1 0.2 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ORZ02443.1 - 0.00028 20.5 0.1 0.00037 20.1 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ORZ02443.1 - 0.00057 19.8 0.0 0.00098 19.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.7 ORZ02443.1 - 0.0057 16.7 1.5 0.0086 16.1 1.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon Mu-like_Com PF10122.9 ORZ02443.1 - 0.12 11.8 0.2 0.26 10.8 0.2 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-B_box PF00643.24 ORZ02443.1 - 0.23 11.6 3.5 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 B-box zinc finger zf-ACC PF17848.1 ORZ02443.1 - 0.3 11.2 6.0 1.1 9.3 0.1 2.6 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Nudix_N_2 PF14803.6 ORZ02443.1 - 0.85 9.6 6.2 1.8 8.5 0.6 2.7 3 0 0 3 3 3 0 Nudix N-terminal Lipase_GDSL PF00657.22 ORZ02444.1 - 4.4e-07 30.1 0.0 5.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORZ02444.1 - 6.3e-05 23.4 0.0 0.0007 20.0 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family PSD3 PF07626.11 ORZ02444.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) Amidohydro_1 PF01979.20 ORZ02445.1 - 2e-65 221.4 1.3 2.5e-65 221.1 1.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORZ02445.1 - 2.8e-21 76.5 0.3 5.7e-14 52.5 0.0 2.7 1 1 0 2 2 2 2 Amidohydrolase family Lactate_perm PF02652.14 ORZ02446.1 - 1.2e-130 436.8 25.7 7.7e-130 434.1 25.7 1.9 1 1 0 1 1 1 1 L-lactate permease DUF4199 PF13858.6 ORZ02446.1 - 0.0059 17.0 0.0 0.0059 17.0 0.0 5.1 4 1 1 5 5 5 2 Protein of unknown function (DUF4199) MFS_1 PF07690.16 ORZ02447.1 - 1e-20 74.0 36.6 1.1e-19 70.6 36.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORZ02447.1 - 3.2e-06 26.0 33.7 3.8e-05 22.4 13.6 2.3 2 1 1 3 3 3 2 MFS/sugar transport protein ParBc PF02195.18 ORZ02448.1 - 4.5e-09 36.5 0.0 5.5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Mito_carr PF00153.27 ORZ02450.1 - 1.2e-53 178.9 2.8 2.5e-19 69.0 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.29 ORZ02451.1 - 9.6e-67 220.7 10.6 1.9e-11 43.6 0.2 8.8 9 0 0 9 9 9 7 KH domain KH_2 PF07650.17 ORZ02451.1 - 1e-07 31.6 5.4 0.03 14.1 0.3 4.7 3 1 1 4 4 4 3 KH domain KH_5 PF13184.6 ORZ02451.1 - 0.1 12.7 0.2 2 8.5 0.0 3.1 3 0 0 3 3 3 0 NusA-like KH domain DIE2_ALG10 PF04922.12 ORZ02452.1 - 3.2e-116 388.9 24.8 4.2e-116 388.5 24.8 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Methyltransf_12 PF08242.12 ORZ02453.1 - 1.8e-06 28.6 0.0 1e-05 26.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ02453.1 - 1.8e-06 28.6 0.0 7.7e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.16 ORZ02453.1 - 5.1e-06 25.8 0.0 7.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.6 ORZ02453.1 - 2.6e-05 24.1 0.0 5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ02453.1 - 6.6e-05 22.8 0.0 0.0002 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ02453.1 - 0.00016 22.3 0.1 0.0014 19.2 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain G10 PF01125.17 ORZ02454.1 - 1.8e-70 235.4 2.7 1.9e-70 235.3 2.7 1.0 1 0 0 1 1 1 1 G10 protein NADH_B2 PF14813.6 ORZ02455.1 - 0.0037 17.0 2.1 0.0045 16.7 2.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 ORZ02457.1 - 1.3e-54 185.4 0.0 1.5e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02457.1 - 2.2e-29 102.6 0.0 2.4e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ02457.1 - 5.2e-06 26.0 0.2 1.1e-05 24.9 0.2 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORZ02457.1 - 0.004 17.1 0.0 0.94 9.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 ORZ02457.1 - 0.0072 16.0 0.1 0.51 9.9 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORZ02457.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORZ02457.1 - 0.029 14.0 0.0 0.084 12.5 0.0 1.7 1 1 0 1 1 1 0 RIO1 family DnaJ PF00226.31 ORZ02458.1 - 7.6e-11 42.0 0.3 7.1e-10 38.9 0.3 2.1 1 1 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 ORZ02458.1 - 3.9e-06 26.7 18.2 3.9e-06 26.7 18.2 2.7 2 1 0 2 2 2 1 Transmembrane Fragile-X-F protein TGT_C2 PF14810.6 ORZ02459.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Mito_carr PF00153.27 ORZ02460.1 - 1.4e-66 220.5 5.8 1e-21 76.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 ORZ02460.1 - 2.2e-19 69.6 8.7 1.8e-10 41.1 1.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORZ02460.1 - 3.4e-14 51.2 9.7 0.00028 20.2 2.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORZ02460.1 - 3.6e-14 51.4 11.0 0.012 15.5 2.6 4.7 3 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORZ02460.1 - 1.2e-09 37.9 7.8 0.0018 18.0 1.3 4.3 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 ORZ02460.1 - 1.9e-05 23.9 8.3 0.31 10.6 1.2 4.0 4 1 0 4 4 4 3 EF hand EF-hand_10 PF14788.6 ORZ02460.1 - 0.0032 17.3 1.9 0.085 12.7 0.1 3.4 3 1 1 4 4 4 1 EF hand EF-hand_4 PF12763.7 ORZ02460.1 - 0.01 15.8 2.2 0.33 10.9 0.3 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORZ02460.1 - 0.015 15.6 0.4 0.25 11.7 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Serine_protease PF18405.1 ORZ02460.1 - 0.41 9.7 3.3 15 4.6 0.0 3.2 3 1 0 3 3 3 0 Gammaproteobacterial serine protease S1-P1_nuclease PF02265.16 ORZ02461.1 - 0.00069 19.5 0.7 0.00095 19.0 0.7 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease 7TMR-HDED PF07697.11 ORZ02461.1 - 0.094 12.8 4.6 0.12 12.5 4.6 1.1 1 0 0 1 1 1 0 7TM-HD extracellular LPD39 PF18858.1 ORZ02461.1 - 0.19 11.8 9.3 0.25 11.4 9.3 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 ZapB PF06005.12 ORZ02461.1 - 0.4 11.2 6.3 1.4 9.4 6.3 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DUF4407 PF14362.6 ORZ02461.1 - 1.1 8.6 5.3 2.6 7.3 5.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) 2OG-FeII_Oxy_2 PF13532.6 ORZ02462.1 - 8e-25 88.2 0.0 1e-24 87.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VPS11_C PF12451.8 ORZ02463.1 - 7.4e-17 61.3 0.6 1.8e-16 60.1 0.6 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 ORZ02463.1 - 2.9e-16 59.6 20.0 3.4e-16 59.4 5.7 4.0 4 1 0 4 4 4 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 ORZ02463.1 - 1e-08 35.1 6.9 2.5e-08 33.8 6.9 1.7 1 0 0 1 1 1 1 Zinc-finger TPR_11 PF13414.6 ORZ02463.1 - 0.0041 16.8 0.1 0.015 14.9 0.1 2.1 1 0 0 1 1 1 1 TPR repeat zf-C3HC4_2 PF13923.6 ORZ02463.1 - 0.0051 16.6 5.9 0.01 15.7 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 ORZ02463.1 - 0.03 14.8 2.8 0.065 13.7 0.5 2.6 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 TPM_phosphatase PF04536.14 ORZ02463.1 - 0.037 14.2 0.1 0.38 10.9 0.1 2.5 2 0 0 2 2 2 0 TPM domain TPR_12 PF13424.6 ORZ02463.1 - 0.15 12.4 2.4 4.8 7.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 ORZ02463.1 - 0.31 11.4 6.7 0.64 10.4 6.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 ORZ02463.1 - 0.31 11.0 5.9 0.65 10.0 5.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 ORZ02463.1 - 1.3 9.3 4.6 3 8.2 4.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORZ02463.1 - 1.4 9.0 6.0 3 7.9 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger TPR_2 PF07719.17 ORZ02463.1 - 1.7 9.0 8.4 2.8 8.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_18 PF13238.6 ORZ02464.1 - 5.2e-26 91.7 0.1 6.9e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORZ02464.1 - 3.5e-08 34.0 0.8 1.2e-07 32.2 0.4 1.9 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 ORZ02464.1 - 8.1e-06 26.0 0.1 0.0004 20.5 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA PF00004.29 ORZ02464.1 - 7.3e-05 23.2 1.0 0.00016 22.1 0.3 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORZ02464.1 - 0.00022 21.4 0.6 0.0036 17.4 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORZ02464.1 - 0.0004 20.7 0.8 0.0004 20.7 0.8 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORZ02464.1 - 0.00089 19.7 0.0 0.0034 17.8 0.0 1.8 1 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 ORZ02464.1 - 0.00094 19.1 0.3 0.0019 18.1 0.2 1.6 1 1 1 2 2 2 1 NTPase RuvB_N PF05496.12 ORZ02464.1 - 0.004 16.9 0.2 0.0082 15.9 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORZ02464.1 - 0.0056 17.0 0.3 0.011 16.0 0.2 1.7 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORZ02464.1 - 0.0067 15.7 0.4 0.038 13.3 0.1 2.1 2 1 0 2 2 2 1 Zeta toxin dNK PF01712.19 ORZ02464.1 - 0.0096 15.8 1.9 1.3 8.8 0.2 2.2 1 1 0 2 2 2 2 Deoxynucleoside kinase AAA_19 PF13245.6 ORZ02464.1 - 0.0099 16.2 1.6 0.013 15.9 1.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORZ02464.1 - 0.023 14.7 0.2 0.065 13.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 ORZ02464.1 - 0.024 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ORZ02464.1 - 0.025 14.3 0.1 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORZ02464.1 - 0.032 13.3 0.1 0.054 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.17 ORZ02464.1 - 0.035 13.8 0.5 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 ORZ02464.1 - 0.063 12.6 3.7 0.24 10.7 0.8 2.2 2 1 0 2 2 2 0 KaiC AAA_30 PF13604.6 ORZ02464.1 - 0.067 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORZ02464.1 - 0.13 12.3 0.3 0.53 10.4 0.3 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SKI PF01202.22 ORZ02464.1 - 0.14 12.3 0.7 0.4 10.8 0.7 2.0 1 1 0 1 1 1 0 Shikimate kinase Mur_ligase_M PF08245.12 ORZ02464.1 - 0.81 9.6 3.6 0.93 9.4 3.5 1.5 1 1 0 1 1 1 0 Mur ligase middle domain Glyco_transf_49 PF13896.6 ORZ02465.1 - 1.8e-41 142.6 0.1 4.2e-31 108.5 0.0 2.7 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Phosphoesterase PF04185.14 ORZ02466.1 - 4.7e-32 111.6 3.2 3.3e-31 108.8 1.4 2.4 1 1 1 2 2 2 1 Phosphoesterase family RRM_1 PF00076.22 ORZ02468.1 - 4.3e-13 48.9 0.0 5.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ORZ02468.1 - 2.2e-08 34.5 3.5 2.3e-08 34.4 1.3 1.9 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.6 ORZ02468.1 - 0.0041 16.7 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_9 PF14604.6 ORZ02469.1 - 3.3e-09 36.5 0.0 7.3e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 ORZ02469.1 - 4.1e-09 36.6 0.1 1.3e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 ORZ02469.1 - 4.9e-09 35.7 1.4 7.5e-09 35.1 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ORZ02469.1 - 1.5e-07 31.0 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 ORZ02469.1 - 0.032 13.9 6.9 0.081 12.6 6.9 1.7 1 1 0 1 1 1 0 BAR domain of APPL family CobU PF02283.16 ORZ02469.1 - 0.068 12.7 1.9 0.15 11.6 1.9 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Caskin-tail PF16632.5 ORZ02469.1 - 3.3 8.2 5.8 27 5.3 0.5 2.8 2 0 0 2 2 2 0 C-terminal region of Caskin RRM_1 PF00076.22 ORZ02470.1 - 8.8e-21 73.5 0.1 1.2e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ02470.1 - 0.0073 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Wzz PF02706.15 ORZ02471.1 - 0.011 16.0 1.2 0.17 12.2 1.2 2.2 1 1 1 2 2 2 0 Chain length determinant protein 6PGD PF00393.19 ORZ02472.1 - 2.1e-130 434.3 0.0 2.6e-130 434.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORZ02472.1 - 1e-52 178.5 0.0 1.5e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORZ02472.1 - 0.0043 17.6 0.1 0.0098 16.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORZ02472.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 ORZ02473.1 - 2.3e-44 151.8 49.2 2.3e-44 151.8 49.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ02473.1 - 9.2e-16 57.7 12.2 9.2e-16 57.7 12.2 3.2 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORZ02473.1 - 1.7e-09 36.6 27.6 4.9e-09 35.2 27.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 ORZ02475.1 - 2.3e-80 270.6 0.0 2.8e-80 270.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORZ02476.1 - 2e-77 260.9 0.0 2.4e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rhomboid PF01694.22 ORZ02477.1 - 2e-24 86.3 3.6 2e-24 86.3 3.6 1.7 2 0 0 2 2 2 1 Rhomboid family DUF3446 PF11928.8 ORZ02477.1 - 0.68 10.3 8.9 21 5.5 8.1 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain WD40 PF00400.32 ORZ02478.1 - 0.00084 20.1 0.5 7.5 7.6 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Zip PF02535.22 ORZ02479.1 - 9.9e-52 176.2 18.3 5e-51 173.9 18.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter OppC_N PF12911.7 ORZ02479.1 - 3.3 7.8 5.5 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C KH_1 PF00013.29 ORZ02480.1 - 1.8e-44 149.4 5.8 2.2e-16 59.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORZ02480.1 - 1.9e-10 40.4 5.1 0.022 14.6 0.2 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 ORZ02480.1 - 8.3e-10 38.4 1.6 0.034 14.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORZ02480.1 - 9.4e-05 22.4 4.3 0.077 13.1 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Spt20 PF12090.8 ORZ02480.1 - 0.054 13.1 4.6 0.079 12.6 4.6 1.2 1 0 0 1 1 1 0 Spt20 family LIM PF00412.22 ORZ02481.1 - 1.1e-31 108.8 47.0 3.9e-10 39.8 7.1 6.0 5 1 0 5 5 5 5 LIM domain Cytochrom_c3_2 PF14537.6 ORZ02481.1 - 1.3 9.5 0.0 1.3 9.5 0.0 5.9 5 1 0 6 6 6 0 Cytochrome c3 DUF1258 PF06869.12 ORZ02481.1 - 6 6.3 5.8 0.79 9.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) RNA_pol_3_Rpc31 PF11705.8 ORZ02482.1 - 2.7e-15 57.3 0.8 5.5e-15 56.2 0.8 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 F-box-like PF12937.7 ORZ02483.1 - 1.9e-05 24.4 0.0 4.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORZ02483.1 - 0.00078 19.8 9.2 6.5 7.3 0.2 6.7 6 2 1 7 7 7 2 Leucine Rich repeats (2 copies) Transp_inhibit PF18791.1 ORZ02483.1 - 0.015 14.8 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain F-box PF00646.33 ORZ02483.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 ORZ02483.1 - 2.5 7.9 9.8 37 4.2 0.0 5.2 6 1 0 6 6 6 0 Leucine rich repeat SNF2_N PF00176.23 ORZ02484.1 - 2.1e-65 220.8 0.5 4.1e-65 219.8 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 ORZ02484.1 - 7.4e-42 142.9 18.0 7.4e-42 142.9 18.0 3.7 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 ORZ02484.1 - 1.1e-17 64.4 0.4 3.8e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ02484.1 - 1.7e-05 24.9 2.6 2.6e-05 24.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORZ02484.1 - 0.0016 17.7 0.0 0.0016 17.7 0.0 3.2 5 1 0 5 5 5 1 Class II histone deacetylase complex subunits 2 and 3 DBI_PRT PF02277.17 ORZ02484.1 - 0.12 11.6 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyltransferase MyTH4 PF00784.17 ORZ02484.1 - 0.56 10.7 5.9 8.9 6.9 0.3 3.6 3 0 0 3 3 3 0 MyTH4 domain RINGv PF12906.7 ORZ02486.1 - 5.5e-08 32.8 8.9 1.3e-07 31.7 8.9 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 ORZ02486.1 - 0.00087 19.4 4.0 0.0019 18.4 4.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 ORZ02486.1 - 0.0045 17.3 6.6 0.009 16.3 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain VKG_Carbox PF05090.14 ORZ02486.1 - 0.0046 15.9 0.7 0.0069 15.3 0.1 1.5 2 0 0 2 2 2 1 Vitamin K-dependent gamma-carboxylase SUIM_assoc PF16619.5 ORZ02486.1 - 0.039 14.0 10.0 0.13 12.4 10.0 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RBM39linker PF15519.6 ORZ02486.1 - 0.61 11.2 3.7 1.6 9.9 3.7 1.6 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF2076 PF09849.9 ORZ02486.1 - 1.1 9.3 13.9 17 5.3 11.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Suf PF05843.14 ORZ02486.1 - 1.2 9.1 8.6 3.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 ORZ02486.1 - 1.3 10.0 3.9 0.57 11.2 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PHD PF00628.29 ORZ02486.1 - 2.1 8.3 6.9 4 7.4 6.9 1.5 1 0 0 1 1 1 0 PHD-finger SHS2_Rpb7-N PF03876.17 ORZ02487.1 - 6.7e-17 61.6 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORZ02487.1 - 2.8e-12 46.8 0.0 5.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Pyrophosphatase PF00719.19 ORZ02488.1 - 1.1e-58 197.6 0.4 1.5e-58 197.1 0.4 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase HTH_ABP1_N PF18107.1 ORZ02489.1 - 1e-07 31.6 1.2 1.4e-07 31.1 1.2 1.3 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 ORZ02489.1 - 0.0038 17.8 0.1 0.017 15.7 0.2 1.8 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 ORZ02489.1 - 0.016 14.8 0.3 0.33 10.6 0.3 2.5 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 ORZ02489.1 - 0.029 14.4 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Malate_synthase PF01274.22 ORZ02491.1 - 1e-230 766.5 0.1 1.2e-230 766.3 0.1 1.0 1 0 0 1 1 1 1 Malate synthase Sulfate_transp PF00916.20 ORZ02493.1 - 6.2e-93 311.6 21.9 8.4e-93 311.1 21.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORZ02493.1 - 3.5e-23 81.5 0.0 5.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORZ02493.1 - 1.8e-06 28.3 2.9 1.8e-06 28.3 2.9 3.3 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORZ02493.1 - 0.0087 16.4 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain WD40 PF00400.32 ORZ02494.1 - 4e-30 103.4 28.4 2.2e-06 28.3 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ02494.1 - 2e-10 40.8 2.4 0.0015 18.8 0.1 4.8 3 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 ORZ02494.1 - 2.9e-08 33.5 0.8 6.5e-08 32.4 0.8 1.7 1 0 0 1 1 1 1 F-box-like PALB2_WD40 PF16756.5 ORZ02494.1 - 2.5e-05 23.4 1.4 0.085 11.8 0.0 3.4 2 1 0 4 4 4 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 ORZ02494.1 - 0.00015 21.2 0.0 0.11 11.9 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 ORZ02494.1 - 0.0012 17.5 0.4 0.81 8.1 0.1 2.9 2 2 1 3 3 3 2 Cytochrome D1 heme domain F-box PF00646.33 ORZ02494.1 - 0.025 14.4 1.4 0.085 12.8 1.4 2.0 1 1 0 1 1 1 0 F-box domain Pkinase PF00069.25 ORZ02495.1 - 1e-24 87.4 0.0 1.5e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02495.1 - 2.2e-10 40.3 0.0 3.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ02495.1 - 6.5e-09 35.1 2.6 1.4e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Presenilin PF01080.17 ORZ02495.1 - 4 6.1 6.8 5.7 5.6 6.8 1.1 1 0 0 1 1 1 0 Presenilin Aldedh PF00171.22 ORZ02497.1 - 3.8e-13 48.8 5.6 4.1e-11 42.1 2.4 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 ORZ02497.1 - 0.00028 20.1 0.3 0.18 10.8 0.0 2.3 1 1 0 2 2 2 2 Acyl-CoA reductase (LuxC) Cu-oxidase PF00394.22 ORZ02498.1 - 1.4e-32 113.0 0.0 3.3e-32 111.8 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORZ02498.1 - 7.5e-31 106.6 0.3 7.5e-31 106.6 0.3 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORZ02498.1 - 3.9e-21 75.2 13.2 2.2e-19 69.5 2.3 4.3 3 2 0 3 3 3 2 Multicopper oxidase SRF-TF PF00319.18 ORZ02499.1 - 2.7e-24 84.4 0.0 5.1e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AAA PF00004.29 ORZ02500.1 - 5.1e-46 156.4 0.0 2.9e-28 98.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 ORZ02500.1 - 8.6e-29 99.8 0.0 2.4e-28 98.3 0.0 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 ORZ02500.1 - 2.2e-13 49.8 0.3 3.6e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORZ02500.1 - 2.3e-08 34.6 2.4 6.5e-05 23.4 2.6 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 ORZ02500.1 - 1.5e-05 25.2 0.0 0.4 10.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 ORZ02500.1 - 6.6e-05 22.9 0.0 0.00071 19.5 0.1 2.6 2 1 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 ORZ02500.1 - 0.00016 21.5 0.1 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 ORZ02500.1 - 0.00071 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORZ02500.1 - 0.001 19.1 0.0 0.0054 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORZ02500.1 - 0.0011 19.2 0.0 0.054 13.8 0.0 3.4 3 1 1 4 4 3 1 AAA domain DUF815 PF05673.13 ORZ02500.1 - 0.0065 15.7 0.0 0.02 14.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORZ02500.1 - 0.013 16.1 0.0 0.3 11.6 0.0 2.8 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 ORZ02500.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 ORZ02500.1 - 0.016 14.5 0.0 0.058 12.6 0.0 1.9 1 0 0 1 1 1 0 KAP family P-loop domain TsaE PF02367.17 ORZ02500.1 - 0.024 14.7 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 ORZ02500.1 - 0.079 12.9 0.0 0.48 10.3 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ORZ02500.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 ORZ02500.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase Roc PF08477.13 ORZ02500.1 - 0.16 12.2 0.0 0.99 9.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RRM_1 PF00076.22 ORZ02501.1 - 0.0063 16.3 0.0 0.026 14.3 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.17 ORZ02502.1 - 1.2e-38 133.2 0.0 1.9e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 ORZ02502.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 ORZ02502.1 - 0.16 12.7 0.0 0.76 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Redoxin PF08534.10 ORZ02503.1 - 1.2e-27 96.4 0.0 1.4e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORZ02503.1 - 2.3e-05 24.3 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AMP-binding PF00501.28 ORZ02504.1 - 2.1e-106 356.1 0.0 3.1e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ02504.1 - 1.8e-13 51.3 3.7 1e-12 48.9 0.6 3.4 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain SH3_9 PF14604.6 ORZ02504.1 - 0.066 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain DUF547 PF04784.14 ORZ02504.1 - 0.073 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF547 HMG_box PF00505.19 ORZ02505.1 - 1.9e-16 60.2 2.6 3.3e-16 59.5 2.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ02505.1 - 4.5e-08 33.6 2.3 5.6e-08 33.3 1.3 1.7 1 1 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 ORZ02505.1 - 0.037 13.3 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF4653 PF15546.6 ORZ02505.1 - 0.4 10.3 2.7 0.73 9.4 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) PEN-2 PF10251.9 ORZ02506.1 - 4.7e-28 97.4 0.6 5.2e-28 97.3 0.6 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF4212 PF13937.6 ORZ02506.1 - 0.22 11.9 3.9 0.43 11.0 3.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4212) RPA_C PF08784.11 ORZ02507.1 - 1.2e-13 51.6 1.8 4.8e-12 46.4 2.4 2.6 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 ORZ02507.1 - 4.3e-08 33.0 0.2 7.9e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HgmA PF04209.13 ORZ02508.1 - 2.9e-217 721.4 0.1 3.3e-217 721.2 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase ABC_tran_CTD PF16326.5 ORZ02509.1 - 0.038 14.2 10.7 0.47 10.7 0.0 4.1 3 1 2 5 5 5 0 ABC transporter C-terminal domain Tropomyosin PF00261.20 ORZ02509.1 - 0.46 9.8 12.7 0.5 9.7 1.9 3.1 2 1 1 3 3 3 0 Tropomyosin Exonuc_VII_L PF02601.15 ORZ02509.1 - 1.8 8.0 29.0 3.6 7.1 0.3 2.7 2 1 0 2 2 2 0 Exonuclease VII, large subunit CdvA PF18822.1 ORZ02509.1 - 4.4 7.1 10.7 5.5 6.8 7.3 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain FAM184 PF15665.5 ORZ02509.1 - 8.8 6.0 22.7 0.047 13.5 11.9 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Tropomyosin_1 PF12718.7 ORZ02509.1 - 9.1 6.4 22.0 0.027 14.6 10.0 2.5 3 0 0 3 3 3 0 Tropomyosin like RAI16-like PF10257.9 ORZ02510.1 - 1.9e-49 168.5 0.1 2.9e-49 167.9 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Ras PF00071.22 ORZ02511.1 - 1.3e-48 164.7 0.0 1.5e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ02511.1 - 3.6e-31 107.9 0.0 5.4e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ02511.1 - 7.3e-13 48.3 0.0 8.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORZ02511.1 - 4.2e-05 23.6 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORZ02511.1 - 0.00019 21.0 0.1 0.0046 16.5 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORZ02511.1 - 0.00028 20.3 0.0 0.00029 20.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORZ02511.1 - 0.0036 17.2 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 ORZ02511.1 - 0.021 14.4 0.1 1.4 8.5 0.0 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 ORZ02511.1 - 0.024 14.1 0.1 7.5 6.1 0.0 3.0 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.6 ORZ02511.1 - 0.06 13.7 0.0 0.098 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 ORZ02511.1 - 0.069 12.6 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 ORZ02511.1 - 0.15 11.8 0.1 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 ORZ02511.1 - 0.15 11.4 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 AIG1 family Glyco_transf_22 PF03901.17 ORZ02512.1 - 2.6e-42 145.5 16.4 3.6e-42 145.1 16.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 ORZ02512.1 - 0.018 15.3 9.0 0.018 15.3 9.0 1.9 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Polysacc_deac_1 PF01522.21 ORZ02513.1 - 3.1e-25 88.5 0.1 6.6e-25 87.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORZ02513.1 - 0.00021 20.6 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Chitin_synth_2 PF03142.15 ORZ02514.1 - 1.8e-240 799.1 0.6 2.6e-240 798.5 0.6 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORZ02514.1 - 3.2e-06 27.2 9.3 3.2e-06 27.2 9.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORZ02514.1 - 9.2e-06 25.7 0.0 5.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 p450 PF00067.22 ORZ02515.1 - 1.6e-82 277.7 0.4 2e-82 277.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 MS_channel PF00924.18 ORZ02516.1 - 9.6e-18 64.5 0.5 1.6e-17 63.8 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 ORZ02516.1 - 0.00044 20.0 0.6 0.0017 18.1 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 ORZ02516.1 - 0.00064 19.1 1.0 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORZ02516.1 - 0.059 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair Csd3_N PF18059.1 ORZ02516.1 - 0.099 13.2 0.0 0.61 10.6 0.0 2.2 2 0 0 2 2 2 0 Csd3 N-terminal DUF2207 PF09972.9 ORZ02516.1 - 0.11 11.3 2.2 2 7.1 1.5 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3382 PF11862.8 ORZ02516.1 - 0.23 11.8 2.1 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Homeodomain PF00046.29 ORZ02517.1 - 8.6e-19 67.1 2.8 1.4e-18 66.4 0.5 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORZ02517.1 - 0.0019 18.0 0.2 0.0074 16.2 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORZ02517.1 - 0.027 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SMC_Nse1 PF07574.13 ORZ02518.1 - 2e-28 99.6 1.7 8.3e-27 94.3 1.7 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 ORZ02518.1 - 2e-11 44.0 9.6 3e-11 43.4 9.6 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 ORZ02518.1 - 0.00052 20.3 9.6 0.00095 19.4 9.6 1.5 1 0 0 1 1 1 1 Ring finger domain FlaG PF03646.15 ORZ02518.1 - 0.025 14.7 0.9 0.047 13.9 0.9 1.5 1 0 0 1 1 1 0 FlaG protein Cdc6_C PF09079.11 ORZ02518.1 - 0.097 12.7 1.6 0.33 11.0 0.1 2.5 2 1 1 3 3 3 0 CDC6, C terminal winged helix domain zf-HC5HC2H PF13771.6 ORZ02518.1 - 0.11 12.8 5.7 0.27 11.5 5.7 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-UDP PF14569.6 ORZ02518.1 - 0.13 12.3 3.7 0.29 11.3 3.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 ORZ02518.1 - 0.2 11.3 6.2 0.33 10.6 6.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 ORZ02518.1 - 0.25 11.2 7.8 0.48 10.3 7.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DWNN PF08783.11 ORZ02519.1 - 3.6e-29 100.9 0.4 7e-29 99.9 0.4 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 ORZ02519.1 - 8.4e-09 35.1 8.1 8.4e-09 35.1 8.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 ORZ02519.1 - 1e-05 25.3 3.0 2.8e-05 24.0 3.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 ORZ02519.1 - 0.0036 17.1 9.2 0.0036 17.1 9.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORZ02519.1 - 0.0049 16.7 8.8 0.0049 16.7 8.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 ORZ02519.1 - 0.0074 16.2 1.8 0.0074 16.2 1.8 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4 PF00097.25 ORZ02519.1 - 0.0096 15.8 9.2 0.0096 15.8 9.2 2.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SUIM_assoc PF16619.5 ORZ02519.1 - 0.12 12.5 20.1 1.4 9.1 0.0 3.5 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-RING_UBOX PF13445.6 ORZ02519.1 - 0.12 12.4 5.7 0.32 11.0 5.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 ORZ02519.1 - 2.5 8.1 17.5 0.23 11.5 10.4 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 ORZ02519.1 - 5.1 7.5 15.7 0.14 12.5 9.1 1.9 2 0 0 2 2 2 0 Ring finger domain MFS_1 PF07690.16 ORZ02520.1 - 5.7e-44 150.5 26.4 5e-28 98.0 4.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ02520.1 - 3.5e-13 49.2 26.0 2.2e-11 43.3 4.5 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.6 ORZ02520.1 - 2.8e-09 36.0 19.3 1.1e-07 30.8 2.4 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORZ02520.1 - 1.8e-06 27.1 17.9 0.0094 14.8 7.3 3.5 1 1 2 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 ORZ02520.1 - 4.8e-05 22.8 20.3 0.00013 21.4 4.0 2.8 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ORZ02520.1 - 0.032 12.5 0.2 0.032 12.5 0.2 3.7 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2754 PF10953.8 ORZ02520.1 - 0.036 14.3 1.9 0.15 12.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) PsaN PF05479.11 ORZ02520.1 - 0.2 11.8 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF2721 PF11026.8 ORZ02520.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Mito_carr PF00153.27 ORZ02521.1 - 8.9e-62 205.0 0.6 1.9e-23 82.2 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.29 ORZ02523.1 - 0.1 12.4 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 KH domain Aldose_epim PF01263.20 ORZ02524.1 - 2.9e-86 289.5 0.4 3.3e-86 289.3 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_35 PF01301.19 ORZ02525.1 - 8.1e-50 170.2 0.7 1.7e-48 165.9 0.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ORZ02525.1 - 5.8e-12 46.2 0.1 0.00015 22.3 0.1 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 ORZ02525.1 - 0.00069 19.1 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase Asp_protease_2 PF13650.6 ORZ02525.1 - 0.15 12.7 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease SWIB PF02201.18 ORZ02526.1 - 5.4e-25 87.1 1.9 9.3e-25 86.3 0.4 2.3 2 0 0 2 2 2 1 SWIB/MDM2 domain Gp_dh_C PF02800.20 ORZ02527.1 - 3.8e-70 234.6 0.0 5.1e-70 234.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORZ02527.1 - 3.6e-39 133.2 0.0 7.2e-39 132.2 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORZ02527.1 - 0.018 15.1 0.0 0.066 13.3 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3652 PF12372.8 ORZ02532.1 - 0.12 12.3 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Huntingtin protein region Methyltransf_11 PF08241.12 ORZ02535.1 - 0.00017 22.1 0.0 0.00035 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 ORZ02535.1 - 0.0021 17.6 0.6 0.017 14.7 0.6 2.2 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 ORZ02535.1 - 0.0037 18.0 0.1 0.01 16.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORZ02535.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ORZ02535.1 - 0.014 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein CheR PF01739.18 ORZ02535.1 - 0.017 14.6 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain GAGBD PF16828.5 ORZ02535.1 - 0.06 13.4 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 GAG-binding domain on surface antigen zinc_ribbon_6 PF14599.6 ORZ02535.1 - 0.11 12.5 0.6 8.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon LIAS_N PF16881.5 ORZ02536.1 - 2.7e-22 79.2 0.1 5.6e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 ORZ02536.1 - 2.1e-12 47.7 0.2 6.8e-12 46.1 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily PSI_PsaJ PF01701.18 ORZ02537.1 - 0.12 13.0 0.8 0.18 12.4 0.8 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Pyr_redox_2 PF07992.14 ORZ02538.1 - 4.3e-53 180.4 0.0 5.2e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORZ02538.1 - 3e-12 46.9 0.0 2.6e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORZ02538.1 - 0.017 14.3 0.0 0.7 8.9 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ORZ02538.1 - 0.026 13.8 0.0 20 4.3 0.0 3.4 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORZ02538.1 - 0.032 14.5 0.0 2.7 8.3 0.0 3.1 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UCH PF00443.29 ORZ02539.1 - 1.9e-46 158.7 0.0 2.8e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORZ02539.1 - 7.5e-10 38.9 0.0 2.7e-05 24.0 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-rbx1 PF12678.7 ORZ02540.1 - 3.8e-25 87.9 13.0 6.7e-25 87.1 13.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORZ02540.1 - 2.8e-16 59.3 10.7 3.9e-16 58.9 10.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 ORZ02540.1 - 3e-06 27.4 14.6 0.00011 22.5 14.6 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORZ02540.1 - 0.0012 18.7 11.8 0.021 14.7 11.8 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORZ02540.1 - 0.0025 17.6 14.8 0.17 11.7 14.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORZ02540.1 - 0.12 12.2 10.7 0.36 10.7 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORZ02540.1 - 0.5 10.2 16.2 41 4.1 16.2 2.4 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 ORZ02540.1 - 0.59 10.4 9.3 3.1 8.0 9.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 ORZ02540.1 - 0.72 9.9 7.9 2.7 8.1 7.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORZ02540.1 - 1.2 8.8 14.8 0.26 10.9 4.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ORZ02540.1 - 7.3 6.6 12.1 61 3.7 12.1 2.5 1 1 0 1 1 1 0 zinc-RING finger domain Slu7 PF11708.8 ORZ02541.1 - 4.7e-110 367.6 15.6 8.7e-110 366.7 15.6 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor DUF3246 PF11596.8 ORZ02541.1 - 0.05 13.0 0.4 0.078 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CaM_binding PF07839.11 ORZ02541.1 - 0.11 13.3 0.2 0.11 13.3 0.2 3.0 3 1 0 3 3 3 0 Plant calmodulin-binding domain Complex1_LYR PF05347.15 ORZ02542.1 - 0.0004 20.4 0.1 0.00078 19.4 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Aldo_ket_red PF00248.21 ORZ02543.1 - 1.6e-54 185.1 0.0 2.1e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.24 ORZ02543.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF3995 PF13160.6 ORZ02544.1 - 0.02 15.2 1.3 0.046 14.1 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) PRIMA1 PF16101.5 ORZ02544.1 - 0.9 9.6 5.8 0.21 11.6 2.2 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Med17 PF10156.9 ORZ02545.1 - 2.6e-78 263.8 0.2 3.6e-78 263.3 0.2 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Acetyltransf_1 PF00583.25 ORZ02546.1 - 4e-10 39.9 0.0 5.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORZ02546.1 - 1.4e-09 38.2 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORZ02546.1 - 2.1e-07 30.8 0.0 4.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORZ02546.1 - 2.6e-07 30.6 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORZ02546.1 - 0.00031 20.8 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORZ02546.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Troponin-I_N PF11636.8 ORZ02546.1 - 0.19 11.7 0.4 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 Troponin I residues 1-32 zf-C3HC4 PF00097.25 ORZ02547.1 - 8.3e-07 28.8 5.7 1.3e-06 28.1 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORZ02547.1 - 9.8e-07 29.0 6.3 1.6e-06 28.4 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORZ02547.1 - 1.1e-06 28.5 4.6 2.1e-06 27.6 3.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORZ02547.1 - 2.5e-06 27.2 4.3 4.2e-06 26.5 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORZ02547.1 - 5.4e-06 26.1 5.7 4.9e-05 23.1 6.5 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ02547.1 - 4.1e-05 23.5 4.5 7.8e-05 22.6 4.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORZ02547.1 - 0.00028 21.0 7.2 0.00064 19.8 7.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORZ02547.1 - 0.0019 18.0 7.3 0.0089 15.9 7.1 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 UIM PF02809.20 ORZ02547.1 - 0.046 13.7 1.8 0.22 11.5 1.8 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif zf-MIZ PF02891.20 ORZ02547.1 - 0.067 13.0 3.3 0.12 12.1 3.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORZ02547.1 - 0.081 12.8 3.3 0.17 11.7 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 ORZ02547.1 - 0.12 12.5 1.8 0.22 11.7 1.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-ANAPC11 PF12861.7 ORZ02547.1 - 0.16 12.0 1.1 0.29 11.2 1.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORZ02547.1 - 0.17 12.2 4.9 0.37 11.1 4.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 ORZ02547.1 - 0.2 11.8 2.8 0.41 10.8 2.7 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 ORZ02547.1 - 0.43 10.5 2.3 3.7 7.5 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 ORZ02547.1 - 1.7 8.4 7.1 1.7 8.5 4.0 2.5 2 1 0 2 2 2 0 RING-like zinc finger TerY_C PF15616.6 ORZ02547.1 - 2.9 8.0 6.7 18 5.5 6.7 2.1 1 1 0 1 1 1 0 TerY-C metal binding domain UPF0547 PF10571.9 ORZ02547.1 - 3.1 8.0 6.5 3.2 7.9 2.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FAD_binding_1 PF00667.20 ORZ02548.1 - 3.8e-52 177.1 0.0 6.4e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORZ02548.1 - 3.6e-38 131.0 0.3 6.7e-38 130.1 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORZ02548.1 - 1.4e-21 77.1 0.1 1.8e-19 70.4 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ORZ02548.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain ArfGap PF01412.18 ORZ02549.1 - 3.8e-31 107.6 0.6 3.8e-31 107.6 0.6 2.0 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Haem_bd PF14376.6 ORZ02549.1 - 0.046 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Haem-binding domain GATA PF00320.27 ORZ02549.1 - 0.1 12.2 0.5 0.21 11.2 0.5 1.6 1 0 0 1 1 1 0 GATA zinc finger Paired_CXXCH_1 PF09699.10 ORZ02549.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.2 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF4234 PF14018.6 ORZ02550.1 - 0.047 13.8 0.0 4 7.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) BTB PF00651.31 ORZ02551.1 - 6.4e-19 68.2 0.0 2.5e-17 63.1 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 ORZ02551.1 - 2.2e-14 53.4 0.3 8.2e-07 29.1 0.1 3.3 3 0 0 3 3 3 3 BTB And C-terminal Kelch RSN1_TM PF13967.6 ORZ02551.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport Phosphodiest PF01663.22 ORZ02552.1 - 7.9e-77 259.2 1.1 9.1e-77 259.0 1.1 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORZ02552.1 - 0.0016 17.9 0.1 0.032 13.6 0.1 2.5 1 1 0 1 1 1 1 Sulfatase bZIP_2 PF07716.15 ORZ02553.1 - 2.2e-07 30.9 12.5 2.2e-07 30.9 12.5 2.2 1 1 2 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 ORZ02553.1 - 3e-05 24.0 14.8 6.1e-05 23.0 14.8 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORZ02553.1 - 0.00086 19.8 11.8 0.00086 19.8 11.8 1.4 2 0 0 2 2 2 1 bZIP Maf transcription factor AAA_32 PF13654.6 ORZ02553.1 - 0.018 13.9 4.3 0.022 13.6 4.3 1.0 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 ORZ02553.1 - 0.026 14.3 2.0 0.026 14.3 2.0 2.1 1 1 1 2 2 2 0 Septum formation initiator Spc42p PF11544.8 ORZ02553.1 - 0.039 14.0 2.5 0.039 14.0 2.5 2.0 1 1 0 2 2 2 0 Spindle pole body component Spc42p Transcrip_reg PF01709.20 ORZ02553.1 - 0.1 12.0 5.1 0.12 11.8 5.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator YabA PF06156.13 ORZ02553.1 - 0.1 13.2 8.0 0.11 13.1 6.9 1.5 1 1 1 2 2 2 0 Initiation control protein YabA Hydin_ADK PF17213.3 ORZ02553.1 - 0.21 11.9 4.5 0.23 11.7 4.5 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ZapB PF06005.12 ORZ02553.1 - 0.69 10.4 16.0 1.8 9.1 2.7 2.2 1 1 1 2 2 2 0 Cell division protein ZapB CCDC-167 PF15188.6 ORZ02553.1 - 3.2 8.2 8.4 2.5 8.5 7.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DSPc PF00782.20 ORZ02554.1 - 8.6e-41 138.9 0.1 3.6e-27 94.8 0.1 3.0 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORZ02554.1 - 8.2e-07 28.8 0.1 0.00074 19.1 0.1 2.7 3 0 0 3 3 3 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORZ02554.1 - 2.9e-05 24.2 0.2 0.0061 16.7 0.3 2.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Myotub-related PF06602.14 ORZ02554.1 - 0.00062 18.8 0.0 0.33 9.8 0.0 2.3 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain EzrA PF06160.12 ORZ02554.1 - 0.0099 14.1 0.1 0.015 13.5 0.1 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CDKN3 PF05706.12 ORZ02554.1 - 0.019 14.6 0.1 8.6 6.0 0.1 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 ORZ02554.1 - 0.13 11.8 1.5 3.6 7.1 0.1 3.6 5 0 0 5 5 5 0 Tyrosine phosphatase family RNA_pol_Rpb2_45 PF10385.9 ORZ02554.1 - 0.46 10.8 3.1 11 6.3 0.4 2.7 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain SPX PF03105.19 ORZ02555.1 - 2.2e-32 113.5 6.2 1.3e-17 64.8 3.0 3.0 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 ORZ02555.1 - 4.6e-29 101.8 34.5 7e-29 101.2 34.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 ORZ02555.1 - 5.8e-27 94.7 43.0 1.8e-16 60.2 18.5 2.5 2 1 1 3 3 3 2 Citrate transporter PH PF00169.29 ORZ02557.1 - 6.8e-18 65.1 0.7 1.4e-17 64.1 0.7 1.5 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 ORZ02557.1 - 1.4e-14 53.9 0.0 2.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 ORZ02557.1 - 1.4e-13 50.5 0.0 2.8e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 ORZ02557.1 - 5.5e-12 46.0 0.0 1.2e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 ORZ02557.1 - 2.2e-11 43.2 0.1 4.8e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORZ02557.1 - 5e-09 35.7 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 ORZ02557.1 - 2e-07 31.4 3.9 2.1e-05 24.9 3.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_PNT PF02198.16 ORZ02557.1 - 3.6e-05 23.6 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 2 Sterile alpha motif (SAM)/Pointed domain PH_8 PF15409.6 ORZ02557.1 - 0.01 16.1 0.2 0.03 14.6 0.2 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain SAM_Ste50p PF09235.10 ORZ02557.1 - 0.032 14.5 0.2 0.089 13.0 0.0 1.8 2 0 0 2 2 2 0 Ste50p, sterile alpha motif CENP-F_N PF10481.9 ORZ02557.1 - 5.8 6.5 5.3 4 7.0 2.1 2.0 2 0 0 2 2 2 0 Cenp-F N-terminal domain Ammonium_transp PF00909.21 ORZ02559.1 - 3.4e-108 361.9 35.6 4.1e-108 361.6 35.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 ORZ02559.1 - 0.0064 16.5 2.1 0.0064 16.5 2.1 2.6 2 0 0 2 2 2 1 Bacteriophage P21 holin S DUF543 PF04418.12 ORZ02559.1 - 2.6 8.1 5.5 1.2 9.2 1.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF543) TIM21 PF08294.11 ORZ02560.1 - 7.4e-38 129.7 0.0 8.8e-38 129.4 0.0 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 ORZ02560.1 - 1.9e-07 30.8 0.0 3.7e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Septin PF00735.18 ORZ02561.1 - 7.8e-125 415.8 0.8 7.8e-125 415.8 0.8 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORZ02561.1 - 3.3e-08 33.6 0.3 9.8e-08 32.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORZ02561.1 - 3.9e-07 30.1 0.8 0.00015 21.7 0.2 2.8 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORZ02561.1 - 2.2e-06 27.3 1.0 0.00092 18.8 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 ORZ02561.1 - 0.00067 20.2 3.1 0.009 16.5 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 ORZ02561.1 - 0.0011 19.2 0.1 0.0081 16.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORZ02561.1 - 0.0022 18.4 0.2 0.0085 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 ORZ02561.1 - 0.0077 16.4 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 ORZ02561.1 - 0.01 15.2 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 ORZ02561.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.9 2 2 0 2 2 2 0 Dynamin family Ras PF00071.22 ORZ02561.1 - 0.018 14.6 0.5 0.067 12.8 0.0 2.2 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 ORZ02561.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 ORZ02561.1 - 0.053 12.7 0.7 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 ORZ02561.1 - 0.077 12.7 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 ORZ02561.1 - 0.4 10.2 6.7 0.73 9.3 6.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 ORZ02561.1 - 0.74 9.6 2.9 30 4.3 0.0 3.4 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Atg14 PF10186.9 ORZ02561.1 - 1 8.4 8.3 1.6 7.7 8.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRS4 PF10422.9 ORZ02561.1 - 1 8.9 6.3 1.8 8.1 6.3 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Strep_SA_rep PF06696.11 ORZ02561.1 - 1.6 8.8 10.0 0.45 10.6 3.1 2.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF87 PF01935.17 ORZ02561.1 - 3.7 7.6 0.0 3.7 7.6 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain Chs7 PF12271.8 ORZ02564.1 - 1.5e-86 290.4 19.3 6e-51 173.5 12.3 2.0 1 1 1 2 2 2 2 Chitin synthase export chaperone PMT_4TMC PF16192.5 ORZ02564.1 - 0.95 9.0 18.2 2.2 7.8 9.2 2.6 1 1 2 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase SWI-SNF_Ssr4 PF08549.10 ORZ02564.1 - 5.5 5.5 8.4 7.1 5.1 8.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Pex14_N PF04695.13 ORZ02564.1 - 5.6 7.6 11.2 9.8 6.8 11.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ArfGap PF01412.18 ORZ02565.1 - 2.7e-30 104.8 0.3 2.7e-30 104.8 0.3 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Paired_CXXCH_1 PF09699.10 ORZ02565.1 - 0.055 13.2 0.1 0.055 13.2 0.1 1.8 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Haem_bd PF14376.6 ORZ02565.1 - 0.19 11.7 1.9 0.63 10.0 1.9 2.0 1 1 0 1 1 1 0 Haem-binding domain Nucleotid_trans PF03407.16 ORZ02566.1 - 2.6e-24 86.4 0.1 4e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase G-alpha PF00503.20 ORZ02567.1 - 1.2e-123 412.8 6.4 1.4e-123 412.6 6.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORZ02567.1 - 2e-16 59.9 3.0 5.6e-12 45.4 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORZ02567.1 - 0.00077 18.9 3.6 0.018 14.4 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORZ02567.1 - 0.0038 17.4 0.2 2.5 8.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 ORZ02567.1 - 0.0093 15.8 0.0 0.042 13.7 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger AAA_29 PF13555.6 ORZ02567.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORZ02567.1 - 0.033 14.3 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORZ02567.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family BRO1 PF03097.18 ORZ02568.1 - 6.6e-128 426.8 3.4 6.6e-128 426.8 3.4 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORZ02568.1 - 1.5e-58 198.5 24.5 3e-58 197.5 24.5 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Myb_DNA-bind_4 PF13837.6 ORZ02568.1 - 0.13 12.7 0.5 0.46 10.9 0.5 2.0 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain EDR1 PF14381.6 ORZ02568.1 - 2.5 7.8 4.4 2.3 7.9 2.0 2.1 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 HA2 PF04408.23 ORZ02569.1 - 3.5e-20 72.3 0.0 9e-20 71.0 0.0 1.8 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORZ02569.1 - 6.2e-13 49.1 0.0 1.6e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ORZ02569.1 - 3.7e-10 40.0 0.0 1.3e-09 38.2 0.0 2.0 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ORZ02569.1 - 1.4e-05 25.0 0.2 3.8e-05 23.5 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ORZ02569.1 - 4.5e-05 23.8 0.1 0.0001 22.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORZ02569.1 - 6e-05 23.3 0.1 0.00021 21.6 0.1 2.0 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORZ02569.1 - 0.002 18.0 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain T2SSE PF00437.20 ORZ02569.1 - 0.019 14.0 0.1 0.079 12.0 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 ORZ02569.1 - 0.06 13.4 0.1 0.28 11.2 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 ORZ02569.1 - 0.11 12.9 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rubredoxin_2 PF18073.1 ORZ02569.1 - 0.15 11.8 0.5 0.34 10.7 0.5 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain AAA_16 PF13191.6 ORZ02569.1 - 0.42 11.0 3.0 0.42 11.0 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain ATP-synt_C PF00137.21 ORZ02570.1 - 8.6e-32 109.3 32.3 4.6e-19 68.5 11.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 ORZ02570.1 - 3.6 5.9 5.8 0.3 9.5 0.8 1.6 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.6 ORZ02570.1 - 4.5 7.6 12.3 5 7.5 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Sec1 PF00995.23 ORZ02571.1 - 3.1e-117 393.2 0.0 3.7e-117 393.0 0.0 1.1 1 0 0 1 1 1 1 Sec1 family 60KD_IMP PF02096.20 ORZ02571.1 - 0.2 11.6 0.1 0.38 10.6 0.1 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein DUF3067 PF11267.8 ORZ02572.1 - 0.0022 18.5 0.1 0.0024 18.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) GATA PF00320.27 ORZ02574.1 - 0.0076 15.8 9.4 0.0076 15.8 9.4 2.6 2 1 0 2 2 2 1 GATA zinc finger Ribosomal_S10 PF00338.22 ORZ02575.1 - 2e-28 98.5 0.7 2.4e-28 98.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2540 PF10802.8 ORZ02575.1 - 0.083 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) DUF3425 PF11905.8 ORZ02576.1 - 1e-12 48.1 0.3 5.7e-12 45.7 0.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) SOGA PF11365.8 ORZ02576.1 - 0.69 11.1 3.9 0.29 12.3 0.7 2.0 2 0 0 2 2 2 0 Protein SOGA bZIP_1 PF00170.21 ORZ02576.1 - 4.6 7.4 25.1 0.33 11.1 16.9 2.8 3 1 1 4 4 4 0 bZIP transcription factor DUF3425 PF11905.8 ORZ02577.1 - 1.6e-13 50.7 0.9 1.1e-12 48.0 0.9 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORZ02577.1 - 4e-07 30.0 6.3 1.1e-06 28.6 6.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.13 ORZ02577.1 - 0.041 13.7 0.2 0.14 12.0 0.2 1.9 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain INCENP_ARK-bind PF03941.15 ORZ02577.1 - 1.1 9.2 8.1 4.2 7.4 8.1 2.0 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region bZIP_2 PF07716.15 ORZ02577.1 - 2.8 8.1 12.3 4.3 7.5 11.0 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Nnf1 PF03980.14 ORZ02577.1 - 2.9 8.3 10.5 2.7 8.4 0.5 3.1 3 0 0 3 3 3 0 Nnf1 MaoC_dehydrat_N PF13452.6 ORZ02578.1 - 2e-05 24.8 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 ORZ02578.1 - 0.0026 17.3 0.1 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain G-alpha PF00503.20 ORZ02579.1 - 1.4e-108 363.2 0.0 1.9e-108 362.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORZ02579.1 - 7e-09 35.4 2.3 7e-08 32.1 0.1 2.8 3 1 0 3 3 3 1 ADP-ribosylation factor family Sugar_tr PF00083.24 ORZ02580.1 - 5e-133 444.3 25.7 5.8e-133 444.1 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ02580.1 - 1.5e-29 103.1 42.9 1.3e-25 90.0 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORZ02580.1 - 8.8 4.6 12.9 0.61 8.4 7.2 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector RhoGAP PF00620.27 ORZ02581.1 - 6.1e-32 110.6 0.0 7.9e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Arrestin_C PF02752.22 ORZ02582.1 - 5e-14 52.9 0.1 3.8e-10 40.3 0.1 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORZ02582.1 - 6.7e-13 48.9 0.1 1.2e-08 35.1 0.1 3.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DOMON PF03351.17 ORZ02583.1 - 0.039 14.2 0.0 0.052 13.8 0.0 1.3 1 1 0 1 1 1 0 DOMON domain Exo_endo_phos PF03372.23 ORZ02584.1 - 8.7e-11 41.8 0.0 2.6e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ThrE PF06738.12 ORZ02585.1 - 6.6e-49 166.5 30.3 2e-45 155.0 4.5 2.9 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORZ02585.1 - 0.00043 20.4 34.2 0.014 15.5 15.7 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF5385 PF17359.2 ORZ02585.1 - 0.005 16.4 0.9 0.0098 15.5 0.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5385) DUF3987 PF13148.6 ORZ02585.1 - 0.27 10.2 2.1 0.45 9.5 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.10 ORZ02585.1 - 1.2 9.2 5.1 2.8 8.0 5.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CitMHS_2 PF16980.5 ORZ02586.1 - 0.1 11.2 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative citrate transport PNP_UDP_1 PF01048.20 ORZ02586.1 - 0.1 11.8 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Phosphorylase superfamily Cnd2 PF05786.14 ORZ02587.1 - 1.5e-159 533.1 39.9 4.3e-158 528.3 39.9 2.7 1 1 0 1 1 1 1 Condensin complex subunit 2 DnaA_N PF11638.8 ORZ02587.1 - 0.11 12.2 0.9 31 4.4 0.1 3.3 3 0 0 3 3 3 0 DnaA N-terminal domain CNDH2_N PF06278.11 ORZ02587.1 - 0.17 12.1 0.0 0.17 12.1 0.0 3.1 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Presenilin PF01080.17 ORZ02587.1 - 9.4 4.9 11.6 21 3.7 11.6 1.6 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 ORZ02588.1 - 9.1e-16 58.2 1.0 1e-07 32.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORZ02588.1 - 6.2e-15 55.3 6.2 6.3e-09 36.2 0.6 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ02588.1 - 2.8e-10 39.5 8.0 0.021 15.3 0.2 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 ORZ02588.1 - 9.6e-10 38.5 3.2 0.00074 19.8 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORZ02588.1 - 1e-08 35.2 9.6 0.0067 16.8 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Dicty_REP PF05086.12 ORZ02588.1 - 0.14 10.1 0.8 0.21 9.5 0.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CAP_N PF01213.19 ORZ02592.1 - 0.54 9.7 10.8 0.11 12.0 7.3 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TMEM171 PF15471.6 ORZ02592.1 - 0.68 8.9 4.6 1.3 7.9 4.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Mito_fiss_reg PF05308.11 ORZ02592.1 - 1.6 8.8 9.6 0.057 13.5 3.5 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator PRIMA1 PF16101.5 ORZ02592.1 - 2.7 8.1 6.0 5.9 6.9 6.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 UBN_AB PF14075.6 ORZ02594.1 - 1.5e-19 70.6 5.5 4.7e-13 49.4 0.4 3.3 3 1 1 4 4 4 2 Ubinuclein conserved middle domain HUN PF08729.10 ORZ02594.1 - 1.1e-08 34.9 0.9 1.1e-08 34.9 0.9 2.1 2 0 0 2 2 2 1 HPC2 and ubinuclein domain MID_MedPIWI PF18296.1 ORZ02594.1 - 2.7 7.7 12.4 3 7.6 1.6 2.5 2 0 0 2 2 2 0 MID domain of medPIWI Mitofilin PF09731.9 ORZ02594.1 - 8 5.2 20.1 1.1 8.0 7.7 2.7 3 0 0 3 3 3 0 Mitochondrial inner membrane protein RFC1 PF08519.12 ORZ02595.1 - 1.3e-44 152.1 0.7 7.8e-44 149.6 0.1 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 ORZ02595.1 - 6.5e-12 46.0 0.0 1.9e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORZ02595.1 - 1.1e-09 38.5 0.0 4.3e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain BRCT PF00533.26 ORZ02595.1 - 7.9e-08 32.6 0.0 2.8e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.6 ORZ02595.1 - 0.00037 20.8 0.0 0.0013 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORZ02595.1 - 0.00042 20.1 0.1 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORZ02595.1 - 0.00081 19.9 0.1 0.0045 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORZ02595.1 - 0.0014 18.4 0.1 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ORZ02595.1 - 0.0026 17.8 0.0 0.0085 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ02595.1 - 0.0046 17.4 0.0 0.023 15.1 0.0 2.2 3 0 0 3 3 1 1 AAA ATPase domain AAA_7 PF12775.7 ORZ02595.1 - 0.0088 15.6 0.0 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 ORZ02595.1 - 0.0092 16.1 0.0 0.059 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORZ02595.1 - 0.01 15.8 0.0 0.035 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ORZ02595.1 - 0.011 15.6 0.1 0.24 11.3 0.0 2.8 2 1 0 2 2 2 0 NACHT domain DNA_pol3_delta PF06144.13 ORZ02595.1 - 0.046 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PTCB-BRCT PF12738.7 ORZ02595.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain RNA_helicase PF00910.22 ORZ02595.1 - 0.076 13.4 0.0 2.2 8.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NTPase_1 PF03266.15 ORZ02595.1 - 0.079 12.9 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 ORZ02595.1 - 0.081 12.3 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SKI PF01202.22 ORZ02595.1 - 0.16 12.1 0.9 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase AAA_17 PF13207.6 ORZ02595.1 - 0.19 12.1 1.9 0.47 10.9 0.0 2.7 3 0 0 3 3 1 0 AAA domain Adaptin_binding PF10199.9 ORZ02596.1 - 3.9e-10 40.4 5.3 8.1e-10 39.4 5.3 1.5 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 MBOAT PF03062.19 ORZ02597.1 - 4.7e-42 144.6 10.5 8.1e-42 143.8 10.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family zf-C3HC4_3 PF13920.6 ORZ02598.1 - 1.5e-06 27.9 10.8 2.9e-06 27.0 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ02598.1 - 7.7e-06 25.7 13.1 7.7e-06 25.7 13.1 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORZ02598.1 - 1.4e-05 24.8 12.1 2.7e-05 23.9 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ02598.1 - 1.5e-05 24.8 12.7 3e-05 23.9 12.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORZ02598.1 - 0.00018 21.8 11.5 0.00035 20.8 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 ORZ02598.1 - 0.00086 19.1 6.0 0.0018 18.1 6.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein FlxA PF14282.6 ORZ02598.1 - 0.0015 18.5 5.2 0.0015 18.5 5.2 7.0 4 2 3 7 7 6 1 FlxA-like protein zf-RING_UBOX PF13445.6 ORZ02598.1 - 0.0015 18.5 10.8 0.0034 17.4 10.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORZ02598.1 - 0.0017 18.2 9.9 0.0031 17.3 9.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORZ02598.1 - 0.016 15.5 8.3 0.055 13.8 8.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain GyrI-like PF06445.15 ORZ02598.1 - 0.07 13.4 0.2 0.17 12.2 0.2 1.6 1 0 0 1 1 1 0 GyrI-like small molecule binding domain DUF3450 PF11932.8 ORZ02598.1 - 0.98 8.7 67.8 0.46 9.7 7.5 6.4 5 1 1 6 6 6 0 Protein of unknown function (DUF3450) zf-C3HC4_4 PF15227.6 ORZ02598.1 - 1.3 9.2 9.9 2.9 8.1 9.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Spc7 PF08317.11 ORZ02598.1 - 2.7 6.8 84.9 0.16 10.9 8.6 6.5 3 1 4 7 7 7 0 Spc7 kinetochore protein zf-C3HC4_5 PF17121.5 ORZ02598.1 - 3.4 7.6 7.1 6 6.8 7.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fib_alpha PF08702.10 ORZ02598.1 - 4.2 7.5 51.6 2.9 8.1 0.7 7.0 4 3 3 7 7 7 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 ORZ02598.1 - 9.2 6.3 41.7 0.84 9.7 1.1 7.1 4 3 4 8 8 8 0 Protein of unknown function (DUF1664) zf-RING_4 PF14570.6 ORZ02598.1 - 9.3 6.1 10.8 0.6 9.9 4.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Peptidase_C50 PF03568.17 ORZ02599.1 - 2.4e-18 66.4 0.1 3.1e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 ORZ02599.1 - 0.00092 18.7 0.0 0.00095 18.7 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.17 ORZ02600.1 - 1.3e-59 202.3 0.0 1.8e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 Ribonuclease_P PF00825.18 ORZ02600.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease P RCSD PF05177.12 ORZ02602.1 - 0.043 14.7 0.1 0.09 13.7 0.1 1.5 1 0 0 1 1 1 0 RCSD region Abhydrolase_3 PF07859.13 ORZ02603.1 - 2.8e-18 66.6 0.1 4.6e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORZ02603.1 - 1.6e-14 53.7 2.4 6.1e-14 51.8 2.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORZ02603.1 - 2e-09 37.2 0.8 4.9e-06 26.2 0.0 3.0 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORZ02603.1 - 1.8e-05 24.7 0.0 0.00051 19.9 0.1 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 ORZ02603.1 - 1.9e-05 23.7 0.0 4.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme FSH1 PF03959.13 ORZ02603.1 - 8.9e-05 22.2 0.1 0.00022 21.0 0.1 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ORZ02603.1 - 0.00021 20.7 1.1 0.011 15.0 1.1 3.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORZ02603.1 - 0.00073 20.2 0.0 0.0013 19.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 ORZ02603.1 - 0.003 16.6 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase LIDHydrolase PF10230.9 ORZ02603.1 - 0.011 15.3 0.6 3.4 7.1 0.3 2.4 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase DUF1749 PF08538.10 ORZ02603.1 - 0.021 13.9 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 ORZ02603.1 - 0.026 14.2 0.2 0.32 10.6 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 ORZ02603.1 - 0.028 13.9 0.3 8.9 5.7 0.2 2.7 2 1 0 2 2 2 0 Esterase PHB depolymerase BAAT_C PF08840.11 ORZ02603.1 - 0.049 13.5 0.1 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 ORZ02603.1 - 0.092 12.3 0.2 2.9 7.4 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 ORZ02603.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) RicinB_lectin_2 PF14200.6 ORZ02604.1 - 1.5e-16 60.9 2.1 1.9e-10 41.3 0.2 2.7 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ORZ02604.1 - 1.1e-14 54.7 1.5 1.8e-14 54.1 1.5 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF3277 PF11681.8 ORZ02604.1 - 0.021 14.7 0.5 0.034 14.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Pkinase PF00069.25 ORZ02605.1 - 3.3e-69 233.2 0.0 4.5e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02605.1 - 4.9e-29 101.4 0.0 7.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ02605.1 - 5.4e-07 29.2 0.4 0.00016 21.1 0.2 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 ORZ02605.1 - 0.00059 19.5 0.1 0.001 18.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family DAZAP2 PF11029.8 ORZ02605.1 - 0.0068 17.3 1.0 0.014 16.3 1.0 1.5 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) Kdo PF06293.14 ORZ02605.1 - 0.018 14.4 0.3 0.032 13.6 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORZ02605.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-HIT PF04438.16 ORZ02606.1 - 2.5e-09 36.8 12.4 2.5e-09 36.8 12.4 1.7 2 0 0 2 2 2 1 HIT zinc finger zf-MYND PF01753.18 ORZ02606.1 - 7.5 6.7 18.9 0.39 10.9 13.2 1.9 2 0 0 2 2 2 0 MYND finger ResIII PF04851.15 ORZ02607.1 - 7.8e-22 78.1 0.0 2.5e-21 76.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORZ02607.1 - 1.6e-19 70.3 0.1 3.5e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORZ02607.1 - 4.4e-16 59.1 0.0 2e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORZ02607.1 - 6.1e-06 26.1 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase V-ATPase_C PF03223.15 ORZ02608.1 - 3.6e-127 424.8 11.8 4e-127 424.6 11.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF5390 PF17365.2 ORZ02608.1 - 0.094 13.0 0.3 0.094 13.0 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5390) CHCH PF06747.13 ORZ02609.1 - 9.7e-06 25.6 6.4 9.7e-06 25.6 6.4 1.8 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 ORZ02609.1 - 0.013 15.5 2.2 0.03 14.3 2.2 1.6 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2076 PF09849.9 ORZ02609.1 - 0.024 14.7 37.8 0.13 12.3 37.8 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MTCP1 PF08991.10 ORZ02609.1 - 0.029 14.6 4.4 0.049 13.9 4.4 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CDC27 PF09507.10 ORZ02609.1 - 0.13 11.6 9.6 0.16 11.4 9.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GET2 PF08690.10 ORZ02609.1 - 5.4 6.6 13.2 6.7 6.3 13.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 6PGD PF00393.19 ORZ02610.1 - 6.5e-124 413.0 0.0 9.3e-124 412.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORZ02610.1 - 7.7e-52 175.6 0.0 1.1e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORZ02610.1 - 0.0027 18.3 0.0 0.014 16.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORZ02610.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORZ02610.1 - 0.21 11.7 0.9 0.51 10.4 0.1 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Muted PF14942.6 ORZ02613.1 - 6.8e-05 23.3 2.0 0.0001 22.7 2.0 1.2 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Latarcin PF10279.9 ORZ02613.1 - 0.0017 18.7 2.3 0.0044 17.4 2.3 2.0 1 1 0 1 1 1 1 Latarcin precursor DNA_ligase_A_N PF04675.14 ORZ02613.1 - 0.0032 17.8 0.4 0.0064 16.8 0.3 1.5 1 1 1 2 2 2 1 DNA ligase N terminus DUF812 PF05667.11 ORZ02613.1 - 0.0049 15.8 1.3 0.0052 15.7 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) YwhD PF08741.10 ORZ02613.1 - 0.033 13.9 0.1 0.061 13.0 0.1 1.7 1 1 0 1 1 1 0 YwhD family ACP_PD PF04336.12 ORZ02613.1 - 0.055 13.9 1.3 20 5.7 0.0 3.0 1 1 2 3 3 3 0 Acyl carrier protein phosphodiesterase DUF4855 PF16147.5 ORZ02613.1 - 0.056 12.5 0.3 0.068 12.2 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4855) MT0933_antitox PF14013.6 ORZ02613.1 - 0.1 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 MT0933-like antitoxin protein Rnk_N PF14760.6 ORZ02613.1 - 0.1 13.1 2.4 4 8.0 0.0 2.4 2 0 0 2 2 2 0 Rnk N-terminus PDEase_II PF02112.15 ORZ02613.1 - 0.18 10.9 0.1 0.76 8.8 0.0 1.8 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II PAP_central PF04928.17 ORZ02613.1 - 0.2 10.6 1.8 0.32 9.9 1.7 1.4 1 1 0 1 1 1 0 Poly(A) polymerase central domain FUSC PF04632.12 ORZ02613.1 - 0.28 9.7 5.3 0.33 9.4 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MutS_IV PF05190.18 ORZ02613.1 - 0.29 11.5 3.8 4.4 7.7 0.1 2.6 2 1 0 2 2 2 0 MutS family domain IV FliT PF05400.13 ORZ02613.1 - 0.48 11.3 6.9 0.35 11.7 4.2 1.9 2 0 0 2 2 2 0 Flagellar protein FliT Ank_2 PF12796.7 ORZ02614.1 - 2.3e-10 40.9 0.1 5.5e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORZ02614.1 - 4.3e-09 35.9 0.5 2.3e-06 27.5 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 ORZ02614.1 - 2.7e-08 33.9 0.4 4.3e-07 30.1 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORZ02614.1 - 4.8e-08 33.4 0.1 1.8e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORZ02614.1 - 5.4e-07 29.8 0.2 6e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ribosomal_L27A PF00828.19 ORZ02615.1 - 2e-20 73.8 0.2 2.6e-20 73.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A F-box-like PF12937.7 ORZ02616.1 - 4.2e-08 33.0 3.6 4.2e-08 33.0 3.6 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORZ02616.1 - 4.9e-08 32.7 3.3 9.9e-08 31.7 3.3 1.6 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 ORZ02616.1 - 0.00038 20.4 2.8 0.0016 18.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ02616.1 - 0.0058 17.4 0.3 0.024 15.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 ORZ02616.1 - 0.011 14.7 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 F-box_5 PF18511.1 ORZ02616.1 - 0.067 12.8 0.3 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 F-box TPR_17 PF13431.6 ORZ02616.1 - 0.11 13.0 0.6 0.57 10.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ02616.1 - 0.15 11.9 2.1 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 ORZ02617.1 - 1.9e-67 228.2 3.9 2.3e-67 228.0 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 ORZ02617.1 - 0.0012 18.3 0.1 0.0019 17.7 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 85 DUF4849 PF16141.5 ORZ02617.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 RhoGEF PF00621.20 ORZ02618.1 - 1.1e-33 117.0 2.5 2.7e-33 115.7 0.3 2.4 2 0 0 2 2 2 1 RhoGEF domain KELK PF15796.5 ORZ02618.1 - 5.1 7.6 8.4 1.1 9.8 1.8 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PUF PF00806.19 ORZ02619.1 - 1.7e-19 68.3 0.1 7.5e-06 25.4 0.0 6.8 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat NTS PF15447.6 ORZ02619.1 - 0.083 13.4 0.3 0.43 11.1 0.3 2.3 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 Dfp1_Him1_M PF08630.10 ORZ02620.1 - 2.7e-21 76.1 0.0 2.7e-21 76.1 0.0 2.8 2 1 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 ORZ02620.1 - 1.6e-16 60.1 1.9 2.9e-16 59.3 1.9 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 ORZ02620.1 - 0.0043 17.4 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORZ02620.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Mucin PF01456.17 ORZ02620.1 - 0.76 9.8 20.1 2.1 8.3 20.1 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3530 PF12048.8 ORZ02620.1 - 2.7 7.3 26.4 0.073 12.5 3.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3530) WD40 PF00400.32 ORZ02621.1 - 2.8e-30 103.9 11.3 9.8e-05 23.1 0.0 10.4 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ02621.1 - 9.3e-06 25.9 0.0 0.92 9.9 0.0 4.9 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ02621.1 - 0.092 12.1 0.4 8.8 5.6 0.0 2.9 3 1 0 3 3 3 0 WD40-like domain Syja_N PF02383.18 ORZ02622.1 - 4.3e-71 239.8 0.0 6.3e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 ORZ02622.1 - 1.3e-05 24.8 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_H_20C_C PF18088.1 ORZ02623.1 - 2.7e-48 164.4 0.4 4.7e-48 163.6 0.4 1.4 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 ORZ02623.1 - 8.2e-11 41.9 0.0 8.3e-10 38.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain UbiA PF01040.18 ORZ02624.1 - 1.7e-51 175.0 10.8 2.3e-51 174.5 10.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Erg28 PF03694.13 ORZ02625.1 - 5.1e-39 133.1 1.9 6.4e-39 132.7 1.9 1.1 1 0 0 1 1 1 1 Erg28 like protein EOS1 PF12326.8 ORZ02625.1 - 0.013 15.4 0.2 0.049 13.6 0.0 1.8 1 1 1 2 2 2 0 N-glycosylation protein Arrestin_N PF00339.29 ORZ02627.1 - 1.5e-09 38.0 0.1 7.8e-05 22.8 0.0 3.5 2 2 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORZ02627.1 - 0.00013 22.4 0.1 0.0018 18.7 0.1 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORZ02627.1 - 0.017 14.3 0.1 4.2 6.4 0.0 2.5 1 1 1 2 2 2 0 Rgp1 KilA-N PF04383.13 ORZ02628.1 - 0.00012 21.9 0.1 0.00063 19.6 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain Hexokinase_2 PF03727.16 ORZ02629.1 - 1e-78 264.1 0.0 1.4e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORZ02629.1 - 5.1e-66 222.4 0.0 7.1e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Thioredoxin PF00085.20 ORZ02631.1 - 1e-43 147.5 0.6 1.1e-23 83.2 0.1 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 ORZ02631.1 - 4.7e-15 56.0 0.0 6.9e-12 45.7 0.0 3.5 2 1 2 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ORZ02631.1 - 1.1e-07 31.5 0.4 0.00018 21.0 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORZ02631.1 - 1.9e-06 28.3 3.4 0.023 15.1 0.1 4.3 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORZ02631.1 - 0.00013 22.2 0.4 0.088 13.1 0.0 4.1 4 1 0 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 ORZ02631.1 - 0.00039 20.5 1.1 0.24 11.6 0.1 3.4 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 ORZ02631.1 - 0.0041 17.0 0.2 0.068 13.1 0.0 2.6 2 0 0 2 2 2 1 AhpC/TSA family TraF PF13728.6 ORZ02631.1 - 0.077 12.8 0.2 11 5.8 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 ORZ02631.1 - 2.9 8.2 5.1 13 6.0 0.1 3.4 4 0 0 4 4 4 0 Glutaredoxin GLE1 PF07817.13 ORZ02632.1 - 5.5e-44 150.3 0.1 7.4e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 GLE1-like protein PIP5K PF01504.18 ORZ02632.1 - 0.32 10.2 3.3 0.51 9.5 3.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase GCP_N_terminal PF17681.1 ORZ02633.1 - 7.8e-96 321.3 0.2 1.4e-95 320.5 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORZ02633.1 - 2.5e-89 299.8 4.2 2.5e-89 299.8 4.2 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal F-box-like PF12937.7 ORZ02634.1 - 0.0013 18.5 8.9 0.028 14.3 6.2 2.5 1 1 1 2 2 2 2 F-box-like F-box PF00646.33 ORZ02634.1 - 0.0052 16.6 2.6 0.0052 16.6 2.6 2.2 2 1 0 2 2 2 1 F-box domain zf-C2H2 PF00096.26 ORZ02635.1 - 9.4e-07 29.0 12.8 2.4e-05 24.5 2.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ02635.1 - 4e-05 23.8 0.9 4e-05 23.8 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ02635.1 - 0.006 17.3 6.4 1 10.4 1.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORZ02635.1 - 0.048 13.9 1.5 0.2 12.0 0.8 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORZ02635.1 - 0.12 13.1 3.5 0.92 10.2 0.5 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORZ02635.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger HSF_DNA-bind PF00447.17 ORZ02637.1 - 1.5e-31 108.8 0.8 1.5e-31 108.8 0.8 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding Zwint PF15556.6 ORZ02637.1 - 0.02 14.4 0.5 0.037 13.5 0.5 1.5 1 0 0 1 1 1 0 ZW10 interactor Dsh_C PF12316.8 ORZ02637.1 - 0.56 10.6 25.5 1.1 9.6 25.5 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Spem1 PF15670.5 ORZ02637.1 - 1.9 8.0 10.5 1.9 8.0 8.5 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 Presenilin PF01080.17 ORZ02637.1 - 6 5.5 8.1 10 4.7 8.1 1.4 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 ORZ02637.1 - 8.4 4.8 16.5 1.8 7.1 11.3 2.0 2 0 0 2 2 2 0 Macoilin family DC_STAMP PF07782.13 ORZ02638.1 - 0.033 14.0 0.2 0.033 14.0 0.2 1.0 1 0 0 1 1 1 0 DC-STAMP-like protein GATase_2 PF00310.21 ORZ02639.1 - 3.4e-182 605.8 0.0 4.8e-182 605.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ORZ02639.1 - 2e-153 510.9 0.1 4.2e-153 509.8 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ORZ02639.1 - 1.6e-114 382.2 0.1 3.1e-114 381.2 0.1 1.5 2 0 0 2 2 1 1 Glutamate synthase central domain GXGXG PF01493.19 ORZ02639.1 - 2.2e-86 288.3 3.3 3.7e-86 287.6 3.3 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 ORZ02639.1 - 1.4e-28 100.0 0.0 6.6e-28 97.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ORZ02639.1 - 4.5e-22 77.9 0.0 1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 ORZ02639.1 - 2.3e-07 31.0 0.0 7.9e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORZ02639.1 - 3.7e-07 30.6 0.5 0.00083 19.9 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORZ02639.1 - 7.5e-06 25.4 0.6 0.22 10.7 0.1 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORZ02639.1 - 9.9e-06 25.4 0.2 0.0046 16.6 0.1 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORZ02639.1 - 7e-05 21.7 1.8 8.4e-05 21.4 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 ORZ02639.1 - 0.00021 21.7 0.0 1.5 9.3 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding Amino_oxidase PF01593.24 ORZ02639.1 - 0.00024 20.5 0.0 0.00052 19.4 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORZ02639.1 - 0.00057 19.2 0.0 0.026 13.8 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ORZ02639.1 - 0.001 18.5 0.1 0.0023 17.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORZ02639.1 - 0.0016 17.6 1.1 0.0034 16.5 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 ORZ02639.1 - 0.0016 17.7 0.0 0.0045 16.3 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORZ02639.1 - 0.0084 15.4 0.8 0.091 12.0 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 ORZ02639.1 - 0.048 13.7 0.0 27 4.8 0.0 3.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Prot_ATP_ID_OB PF16450.5 ORZ02639.1 - 0.059 13.3 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain 2-Hacid_dh_C PF02826.19 ORZ02639.1 - 0.068 12.5 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ORZ02639.1 - 0.1 12.6 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding GATase_6 PF13522.6 ORZ02639.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain GIDA PF01134.22 ORZ02639.1 - 0.11 11.6 1.0 0.36 9.9 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FMN_dh PF01070.18 ORZ02639.1 - 0.24 10.4 4.0 0.3 10.1 0.5 2.6 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Rossmann-like PF10727.9 ORZ02639.1 - 0.24 11.2 0.9 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Rossmann-like domain F420_oxidored PF03807.17 ORZ02639.1 - 5.7 7.6 6.8 3.9 8.1 0.1 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent TRAPPC9-Trs120 PF08626.11 ORZ02641.1 - 0 1072.9 0.0 0 1072.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_7 PF13176.6 ORZ02641.1 - 0.084 12.9 0.0 0.35 11.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1652 PF07865.11 ORZ02641.1 - 0.17 11.7 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) CRAL_TRIO PF00650.20 ORZ02642.1 - 5.9e-20 71.6 0.1 9.2e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain DUF3537 PF12056.8 ORZ02642.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) SKA2 PF16740.5 ORZ02642.1 - 0.028 14.2 0.9 0.055 13.2 0.1 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 SH3_9 PF14604.6 ORZ02643.1 - 8.2e-10 38.4 0.1 1.6e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORZ02643.1 - 3.7e-08 32.8 0.0 6.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORZ02643.1 - 3.3e-07 29.9 0.0 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_4 PF12763.7 ORZ02643.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 ORZ02644.1 - 2.5e-21 75.9 0.0 5.1e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 ORZ02644.1 - 6.3e-10 38.7 0.5 1.5e-09 37.5 0.5 1.6 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 ORZ02644.1 - 5e-07 29.4 0.0 9.6e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORZ02644.1 - 1.5e-06 28.4 3.0 3.5e-05 23.9 0.5 2.7 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 ORZ02644.1 - 3.7e-06 27.0 0.0 0.00027 20.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 ORZ02644.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 ORZ02644.1 - 0.00041 19.9 0.0 0.1 12.2 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 ORZ02644.1 - 0.0012 18.4 0.0 0.0096 15.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family IIGP PF05049.13 ORZ02644.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GBP PF02263.19 ORZ02644.1 - 0.039 13.2 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain SRPRB PF09439.10 ORZ02644.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ORZ02644.1 - 0.13 12.8 0.2 0.46 11.0 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Bmt2 PF11968.8 ORZ02645.1 - 8.1e-62 208.9 0.0 9.9e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Ribosomal_S4 PF00163.19 ORZ02645.1 - 0.84 10.6 2.5 6.1 7.8 0.1 2.6 2 1 1 3 3 3 0 Ribosomal protein S4/S9 N-terminal domain DUF836 PF05768.14 ORZ02646.1 - 1.4e-14 54.2 0.4 1.7e-14 54.0 0.4 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 ORZ02646.1 - 5.2e-05 23.2 0.2 0.0007 19.5 0.1 1.9 1 1 1 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 ORZ02646.1 - 0.00013 22.1 0.1 0.00019 21.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 ORZ02646.1 - 0.0007 19.6 0.0 0.00092 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF1223 PF06764.11 ORZ02646.1 - 0.0018 18.3 0.1 0.003 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) DUF393 PF04134.12 ORZ02646.1 - 0.043 15.2 0.2 0.056 14.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF393 POR_N PF01855.19 ORZ02646.1 - 0.055 13.2 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Thioredoxin_2 PF13098.6 ORZ02646.1 - 0.073 13.5 0.3 0.1 13.1 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 ORZ02646.1 - 0.082 13.1 0.4 0.18 12.0 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin DSBA PF01323.20 ORZ02646.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 DSBA-like thioredoxin domain HGD-D PF06050.13 ORZ02646.1 - 0.12 12.1 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component G-gamma PF00631.22 ORZ02648.1 - 4.2e-19 68.3 0.0 5e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain PAS_7 PF12860.7 ORZ02648.1 - 0.12 12.5 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 PAS fold MFS_1 PF07690.16 ORZ02649.1 - 1.3e-28 100.0 18.3 1.3e-28 100.0 18.3 3.0 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ02649.1 - 5.8e-17 61.7 2.9 5.8e-17 61.7 2.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORZ02649.1 - 1.3e-06 27.2 5.0 2e-06 26.6 5.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 ORZ02649.1 - 0.00016 20.8 1.2 0.00016 20.8 1.2 2.8 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM MFS_Mycoplasma PF07672.13 ORZ02649.1 - 0.0037 16.6 1.8 0.12 11.6 0.5 2.4 2 0 0 2 2 2 1 Mycoplasma MFS transporter Adipogenin PF15202.6 ORZ02649.1 - 0.12 12.4 0.3 14 5.8 0.4 2.5 2 0 0 2 2 2 0 Adipogenin Fzo_mitofusin PF04799.13 ORZ02649.1 - 0.19 11.2 1.5 0.49 9.9 1.5 1.6 1 0 0 1 1 1 0 fzo-like conserved region BT1 PF03092.16 ORZ02649.1 - 0.28 9.3 6.7 0.64 8.2 0.5 2.3 2 0 0 2 2 2 0 BT1 family DUF485 PF04341.12 ORZ02649.1 - 1.1 9.3 4.5 0.67 9.9 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF485 RNase_H PF00075.24 ORZ02650.1 - 6.9e-19 68.4 0.0 3.6e-18 66.1 0.0 2.0 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 ORZ02650.1 - 0.00069 19.4 0.1 0.0014 18.4 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase-like PLATZ PF04640.14 ORZ02652.1 - 0.0017 18.9 1.5 0.0035 17.9 1.5 1.6 1 0 0 1 1 1 1 PLATZ transcription factor Ecl1 PF12855.7 ORZ02652.1 - 0.0055 17.9 18.1 0.0079 17.4 18.1 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Opiods_neuropep PF01160.18 ORZ02652.1 - 0.15 12.2 1.5 0.26 11.4 1.5 1.4 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Peptidase_M16_C PF05193.21 ORZ02654.1 - 7.5e-45 153.2 0.0 1.2e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORZ02654.1 - 1.7e-41 141.6 0.0 8.9e-41 139.3 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF5429 PF17494.2 ORZ02654.1 - 0.21 11.6 0.9 3.8 7.6 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5429) Aldose_epim PF01263.20 ORZ02656.1 - 6.6e-46 157.0 0.0 7.3e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase SURF4 PF02077.15 ORZ02657.1 - 1.2e-95 320.1 4.9 1.4e-95 319.9 4.9 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 ORZ02657.1 - 1.9 9.1 19.8 0.25 12.0 3.8 3.4 2 1 1 3 3 3 0 DoxX Halogen_Hydrol PF10112.9 ORZ02657.1 - 4.5 7.2 6.7 2.7 8.0 0.1 2.4 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Phage_holin_2_1 PF04971.12 ORZ02657.1 - 5.7 7.0 7.1 0.55 10.3 0.3 2.8 3 0 0 3 3 3 0 Bacteriophage P21 holin S Pet191_N PF10203.9 ORZ02658.1 - 2.6e-27 94.9 5.9 2.9e-27 94.8 5.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 ORZ02658.1 - 0.052 13.5 0.8 0.057 13.3 0.8 1.1 1 0 0 1 1 1 0 COBRA-like protein Cmc1 PF08583.10 ORZ02658.1 - 0.056 13.5 7.1 1.1 9.3 1.5 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 ORZ02658.1 - 0.11 12.8 1.5 0.63 10.3 0.1 2.0 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Dickkopf_N PF04706.12 ORZ02658.1 - 1.9 9.0 8.1 4.3 7.9 1.6 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region GATA PF00320.27 ORZ02661.1 - 3.3e-17 61.8 4.0 6.4e-17 60.9 4.0 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 ORZ02661.1 - 4.6e-14 51.9 1.7 9.6e-14 50.9 1.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ArfGap PF01412.18 ORZ02661.1 - 0.075 13.1 4.5 0.2 11.7 0.1 2.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 ORZ02661.1 - 0.18 11.4 0.3 0.33 10.5 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DivIC PF04977.15 ORZ02661.1 - 2.2 8.1 13.9 6.1 6.7 10.0 2.5 2 0 0 2 2 2 0 Septum formation initiator PSCyt3 PF07627.11 ORZ02661.1 - 7.8 6.8 11.7 3.8 7.8 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) Snapin_Pallidin PF14712.6 ORZ02662.1 - 7.8e-15 55.1 0.3 9.6e-15 54.8 0.3 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Baculo_PEP_C PF04513.12 ORZ02662.1 - 0.0019 18.2 0.5 0.0023 18.0 0.5 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus T7SS_ESX_EspC PF10824.8 ORZ02662.1 - 0.0045 17.4 0.8 0.22 12.0 0.0 2.1 2 0 0 2 2 2 1 Excreted virulence factor EspC, type VII ESX diderm DUF948 PF06103.11 ORZ02662.1 - 0.0054 17.0 0.5 5.4 7.3 0.1 2.4 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF948) TetR_C_31 PF17940.1 ORZ02662.1 - 0.0071 16.5 0.3 0.011 15.9 0.3 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Spc7 PF08317.11 ORZ02662.1 - 0.024 13.5 0.2 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin PF00261.20 ORZ02662.1 - 0.027 13.8 0.9 0.12 11.8 0.3 1.9 2 0 0 2 2 2 0 Tropomyosin DUF1664 PF07889.12 ORZ02662.1 - 0.04 14.0 0.2 0.05 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 ORZ02662.1 - 0.052 13.6 3.8 1.4 9.0 3.3 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DASH_Dam1 PF08653.10 ORZ02662.1 - 0.16 11.8 0.2 0.31 10.9 0.0 1.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Flagellin_N PF00669.20 ORZ02662.1 - 0.22 11.6 7.0 0.12 12.5 1.2 2.2 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Laminin_II PF06009.12 ORZ02662.1 - 0.22 11.5 6.3 9.5 6.2 0.4 2.8 1 1 1 2 2 2 0 Laminin Domain II CLZ PF16526.5 ORZ02662.1 - 1.4 9.3 5.2 12 6.3 0.9 2.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NIBRIN_BRCT_II PF16508.5 ORZ02664.1 - 2.2e-17 63.4 0.0 4.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 ORZ02664.1 - 1.5e-09 38.1 0.0 3.9e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 ORZ02664.1 - 0.0036 17.6 0.0 0.054 13.9 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORZ02664.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Yop-YscD_cpl PF16697.5 ORZ02664.1 - 0.016 15.5 0.0 0.11 12.9 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain MU2_FHA PF18221.1 ORZ02664.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Mutator 2 Fork head associated domain Mito_carr PF00153.27 ORZ02665.1 - 1e-74 246.5 1.4 1.8e-25 88.6 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 ORZ02665.1 - 2.6e-16 58.1 2.0 5e-05 22.9 0.0 6.6 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 ORZ02665.1 - 3.4e-16 57.5 3.3 7.7e-05 22.0 0.0 5.8 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 ORZ02665.1 - 3.2e-14 53.1 8.7 0.00013 22.4 0.1 4.9 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.6 ORZ02665.1 - 4.6e-10 39.2 0.8 0.96 9.3 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 ORZ02665.1 - 0.01 15.3 4.6 0.4 10.3 0.0 4.3 5 0 0 5 5 5 0 EF hand EF-hand_10 PF14788.6 ORZ02665.1 - 0.032 14.1 0.5 4.5 7.2 0.2 2.8 2 1 0 2 2 2 0 EF hand PMBR PF09373.10 ORZ02665.1 - 0.054 13.7 1.1 30 5.0 0.0 4.7 6 0 0 6 6 6 0 Pseudomurein-binding repeat EF-hand_4 PF12763.7 ORZ02665.1 - 0.063 13.2 0.2 7 6.7 0.1 2.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Serine_protease PF18405.1 ORZ02665.1 - 0.17 11.0 0.7 3.3 6.8 0.0 2.9 2 1 0 3 3 3 0 Gammaproteobacterial serine protease PIG-S PF10510.9 ORZ02666.1 - 7.7e-146 486.9 0.0 8.9e-146 486.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Bap31 PF05529.12 ORZ02667.1 - 7.6e-41 139.1 4.2 1.2e-40 138.5 4.2 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 ORZ02667.1 - 6.5e-06 26.1 8.3 6.5e-06 26.1 8.3 2.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5082 PF16888.5 ORZ02667.1 - 0.00073 19.8 6.5 0.0012 19.1 6.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) DUF1980 PF09323.10 ORZ02667.1 - 0.0019 18.2 0.2 0.0028 17.6 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1980) DUF745 PF05335.13 ORZ02667.1 - 0.0093 15.7 6.6 0.069 12.9 5.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF745) GIT_CC PF16559.5 ORZ02667.1 - 0.0098 15.7 1.5 0.019 14.8 1.5 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3450 PF11932.8 ORZ02667.1 - 0.013 14.8 5.2 0.021 14.1 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 ORZ02667.1 - 0.028 14.2 8.7 0.17 11.7 6.8 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 FAM76 PF16046.5 ORZ02667.1 - 0.044 13.1 3.8 0.065 12.6 3.8 1.3 1 0 0 1 1 1 0 FAM76 protein MatE PF01554.18 ORZ02667.1 - 0.33 10.6 3.8 0.54 9.9 3.8 1.3 1 0 0 1 1 1 0 MatE Peptidase_S8 PF00082.22 ORZ02668.1 - 3e-35 122.0 5.0 4.8e-35 121.2 5.0 1.3 1 0 0 1 1 1 1 Subtilase family Lysine_decarbox PF03641.14 ORZ02669.1 - 9.8e-40 135.7 0.0 1.2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ORZ02669.1 - 3.2e-16 59.3 0.1 4.1e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 SLOG cluster4 family MoCF_biosynth PF00994.24 ORZ02669.1 - 0.058 13.0 0.1 0.085 12.5 0.1 1.2 1 0 0 1 1 1 0 Probable molybdopterin binding domain PXA PF02194.15 ORZ02671.1 - 7.1e-23 81.5 3.0 1.6e-22 80.4 0.1 2.5 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 ORZ02671.1 - 1.1e-20 74.3 0.3 1.1e-20 74.3 0.3 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 ORZ02671.1 - 0.0011 18.9 0.0 0.0037 17.2 0.0 1.9 1 0 0 1 1 1 1 PX domain MMTV_SAg PF01054.17 ORZ02671.1 - 0.015 14.9 0.5 0.18 11.3 0.0 2.6 3 0 0 3 3 3 0 Mouse mammary tumour virus superantigen adh_short PF00106.25 ORZ02672.1 - 4.6e-46 156.8 0.8 5.8e-46 156.4 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ02672.1 - 7.1e-32 110.8 0.2 9.4e-32 110.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORZ02672.1 - 6.7e-08 32.3 0.1 3.9e-07 29.8 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORZ02672.1 - 5.9e-06 26.3 0.3 1.5e-05 25.0 0.3 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORZ02672.1 - 0.00035 20.5 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORZ02672.1 - 0.06 12.9 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 ORZ02672.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain BPL_LplA_LipB_2 PF16917.5 ORZ02672.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Kinesin PF00225.23 ORZ02675.1 - 2.3e-77 260.2 0.0 2.3e-77 260.2 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORZ02675.1 - 0.00035 20.5 0.0 0.0012 18.8 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding zf-C2H2 PF00096.26 ORZ02676.1 - 1.8e-06 28.1 8.4 2.1e-05 24.7 1.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 ORZ02676.1 - 0.0011 19.2 0.6 0.0064 16.8 0.9 2.2 2 1 1 3 3 3 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORZ02676.1 - 0.0058 17.2 1.1 0.16 12.6 0.1 2.6 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORZ02676.1 - 0.0094 16.3 1.5 0.0094 16.3 1.5 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ02676.1 - 0.031 15.1 14.3 0.45 11.5 1.0 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Kei1 PF08552.11 ORZ02677.1 - 1.3e-24 87.1 12.9 2e-18 67.0 8.2 2.0 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 AMP-binding PF00501.28 ORZ02678.1 - 2.4e-71 240.6 0.0 3.6e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORZ02678.1 - 7.5e-69 231.7 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ORZ02678.1 - 2.2e-14 53.5 0.0 5.8e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 ORZ02678.1 - 5.2e-11 41.9 0.1 9.3e-10 37.8 0.1 2.1 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 ORZ02678.1 - 4.4e-09 36.2 0.0 7.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORZ02678.1 - 1.2e-07 31.0 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 ORZ02678.1 - 3.1e-07 31.3 0.0 1.2e-06 29.4 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 ORZ02678.1 - 0.016 15.1 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORZ02678.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase eIF3m_C_helix PF18005.1 ORZ02678.1 - 0.12 12.1 0.5 0.27 11.0 0.5 1.7 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix PH_17 PF18012.1 ORZ02678.1 - 0.16 11.7 0.1 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 PH domain Cytochrom_B562 PF07361.11 ORZ02678.1 - 0.16 12.6 0.0 0.42 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b562 Mpv17_PMP22 PF04117.12 ORZ02679.1 - 2e-23 82.4 0.4 2e-23 82.4 0.4 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family MARVEL PF01284.23 ORZ02681.1 - 6.5e-10 39.2 8.2 9.7e-10 38.6 8.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3611 PF12263.8 ORZ02681.1 - 0.047 13.6 2.8 1.2 9.0 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3611) TMEM107 PF14995.6 ORZ02681.1 - 0.062 13.7 1.3 3.5 8.1 0.1 2.7 2 0 0 2 2 2 0 Transmembrane protein TssO PF17561.2 ORZ02681.1 - 0.079 13.1 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO Fasciclin PF02469.22 ORZ02682.1 - 6.9e-36 123.3 3.3 3.1e-10 40.4 0.2 5.2 5 0 0 5 5 5 5 Fasciclin domain ANAPC5 PF12862.7 ORZ02683.1 - 0.0035 17.4 0.3 0.0054 16.8 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 Ribosomal_S15 PF00312.22 ORZ02683.1 - 0.089 13.0 1.3 0.73 10.1 0.1 2.4 3 0 0 3 3 3 0 Ribosomal protein S15 Abhydrolase_3 PF07859.13 ORZ02685.1 - 5.6e-70 235.5 0.3 7.5e-70 235.1 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORZ02685.1 - 1.6e-06 27.3 0.0 2.6e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORZ02685.1 - 1.1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ORZ02685.1 - 0.00035 19.6 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family AXE1 PF05448.12 ORZ02685.1 - 0.025 13.3 0.0 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF1899 PF08953.11 ORZ02685.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Abhydrolase_3 PF07859.13 ORZ02686.1 - 3.2e-09 36.9 0.0 3.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-CHY PF05495.12 ORZ02687.1 - 5.2e-11 42.9 13.4 5.2e-11 42.9 13.4 3.2 3 0 0 3 3 3 2 CHY zinc finger RWD PF05773.22 ORZ02687.1 - 2.9e-10 40.4 0.2 0.00058 20.1 0.0 2.6 2 0 0 2 2 2 2 RWD domain UQ_con PF00179.26 ORZ02687.1 - 0.0094 15.6 0.3 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme zinc_ribbon_4 PF13717.6 ORZ02687.1 - 0.29 11.1 3.3 1.6 8.7 0.4 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Paired_CXXCH_1 PF09699.10 ORZ02687.1 - 9.6 6.0 13.7 7.8 6.3 5.8 2.7 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) RRM_1 PF00076.22 ORZ02688.1 - 1.2e-16 60.3 0.1 9.8e-13 47.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 ORZ02689.1 - 5.8e-52 176.7 0.0 9.5e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02689.1 - 3.4e-51 174.0 0.0 4.3e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.27 ORZ02689.1 - 3.8e-07 29.7 0.3 1.6e-06 27.7 0.1 2.1 2 0 0 2 2 2 1 SAP domain DUF2753 PF10952.8 ORZ02689.1 - 0.00095 19.3 0.1 0.0016 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) APH PF01636.23 ORZ02689.1 - 0.0061 16.5 0.0 0.036 14.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORZ02689.1 - 0.039 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORZ02689.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 ORZ02690.1 - 1.1e-16 60.4 0.0 1.2e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORZ02690.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORZ02690.1 - 0.037 13.6 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORZ02690.1 - 0.055 13.3 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif PGP_phosphatase PF09419.10 ORZ02691.1 - 4.8e-50 169.5 0.0 5.9e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 ORZ02691.1 - 5.3e-07 29.6 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Sel1 PF08238.12 ORZ02692.1 - 1.4e-19 70.1 11.2 3.8e-06 27.4 2.3 4.3 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 ORZ02692.1 - 0.16 12.7 3.6 4.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORZ02692.1 - 0.19 11.8 2.4 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Aldedh PF00171.22 ORZ02693.1 - 3.6e-100 335.6 0.0 4.6e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 ORZ02693.1 - 0.27 11.2 1.0 0.94 9.4 1.0 1.9 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Perilipin PF03036.16 ORZ02694.1 - 0.00026 20.1 0.7 0.0034 16.5 0.0 2.2 1 1 1 2 2 2 2 Perilipin family DUF2063 PF09836.9 ORZ02694.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain Mito_fiss_Elm1 PF06258.11 ORZ02695.1 - 4.8e-19 68.6 0.1 6.6e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 F-box PF00646.33 ORZ02696.1 - 5.4e-11 42.1 0.2 2.4e-10 40.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORZ02696.1 - 2.7e-08 33.6 0.2 2.7e-08 33.6 0.2 2.4 3 0 0 3 3 3 1 F-box-like IBN_N PF03810.19 ORZ02697.1 - 1.2e-08 34.7 2.3 3e-07 30.3 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 ORZ02697.1 - 6e-07 29.2 21.8 0.07 13.4 0.1 9.4 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.6 ORZ02697.1 - 1.7e-05 25.1 4.6 0.34 11.3 0.2 7.0 7 1 2 9 9 9 2 HEAT repeats HEAT_EZ PF13513.6 ORZ02697.1 - 0.00021 21.7 15.5 0.00033 21.1 0.2 6.4 7 0 0 7 7 7 1 HEAT-like repeat Arm PF00514.23 ORZ02697.1 - 0.0015 18.5 3.3 7.5 6.8 0.3 4.7 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 ORZ02697.1 - 0.004 16.7 0.6 0.07 12.7 0.1 3.1 3 1 1 4 4 4 1 Tti2 family MMS19_N PF14500.6 ORZ02697.1 - 0.14 11.7 4.6 2.5 7.6 0.0 4.4 5 1 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II EB1 PF03271.17 ORZ02698.1 - 6.8e-18 64.6 0.5 1.3e-17 63.8 0.5 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORZ02698.1 - 7e-05 23.0 0.1 0.00012 22.3 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 ORZ02698.1 - 0.0013 17.4 0.1 0.0018 16.9 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like FlxA PF14282.6 ORZ02698.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 FlxA-like protein Bromodomain PF00439.25 ORZ02699.1 - 3.2e-52 174.5 0.2 1.7e-25 88.9 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 ORZ02699.1 - 2.1e-21 75.9 1.0 4.3e-21 74.9 1.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AHD PF17793.1 ORZ02699.1 - 0.032 14.0 0.8 0.073 12.9 0.8 1.6 1 0 0 1 1 1 0 ANC1 homology domain (AHD) DAO PF01266.24 ORZ02700.1 - 5.1e-32 111.8 0.0 5.8e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORZ02700.1 - 0.031 14.5 0.2 0.17 12.1 0.2 2.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORZ02700.1 - 0.037 13.1 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 ORZ02700.1 - 0.039 14.5 0.3 0.44 11.1 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORZ02700.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORZ02700.1 - 0.17 12.0 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trehalase PF01204.18 ORZ02701.1 - 5.8e-175 583.0 1.1 7.7e-175 582.6 1.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 ORZ02701.1 - 3.6e-14 52.2 4.6 6.2e-14 51.4 1.6 2.3 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain Syja_N PF02383.18 ORZ02703.1 - 1.2e-82 277.9 0.0 1.5e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain CRAL_TRIO PF00650.20 ORZ02704.1 - 1.2e-32 112.8 0.1 1.8e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORZ02704.1 - 2.7e-11 43.5 1.8 3.7e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORZ02704.1 - 0.00086 19.5 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 ORZ02705.1 - 8.8e-31 106.8 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORZ02705.1 - 4.4e-09 36.4 1.1 4.4e-09 36.4 1.1 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORZ02705.1 - 0.00076 19.7 0.1 0.0013 18.9 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CobW_C PF07683.14 ORZ02705.1 - 0.047 13.6 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain RPAP3_C PF13877.6 ORZ02706.1 - 1.4e-20 73.6 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 ORZ02706.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ02706.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ02706.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat IBR PF01485.21 ORZ02708.1 - 7.1e-06 26.2 17.4 1e-05 25.6 16.9 1.5 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf-ACC PF17848.1 ORZ02708.1 - 0.0025 17.9 0.1 0.0025 17.9 0.1 2.9 3 1 1 4 4 4 1 Acetyl-coA carboxylase zinc finger domain Myb_DNA-bind_4 PF13837.6 ORZ02709.1 - 0.0048 17.3 0.9 0.0087 16.4 0.2 1.8 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain LRR_4 PF12799.7 ORZ02710.1 - 2.6e-10 40.4 1.9 0.017 15.5 0.2 4.7 2 1 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box PF00646.33 ORZ02710.1 - 2.3e-07 30.5 0.6 9.7e-07 28.5 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORZ02710.1 - 7.8e-07 28.9 0.4 2e-06 27.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORZ02710.1 - 1.8e-06 27.5 2.2 0.97 9.7 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 ORZ02710.1 - 9.2e-05 22.5 6.4 0.57 10.9 0.1 5.4 5 1 0 5 5 5 2 Leucine Rich Repeat zf-C3HC4_3 PF13920.6 ORZ02711.1 - 3.8e-06 26.6 5.2 3.8e-06 26.6 5.2 3.6 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Presenilin PF01080.17 ORZ02711.1 - 1.2 7.8 10.9 1.1 7.9 4.2 2.3 2 0 0 2 2 2 0 Presenilin DUF21 PF01595.20 ORZ02712.1 - 1.9e-32 112.4 3.2 2.9e-32 111.8 3.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain HMG14_17 PF01101.18 ORZ02712.1 - 0.078 13.9 2.4 0.16 12.9 2.4 1.4 1 0 0 1 1 1 0 HMG14 and HMG17 Sec34 PF04136.15 ORZ02713.1 - 2.3e-48 163.9 0.4 2.3e-48 163.9 0.4 2.7 3 0 0 3 3 3 1 Sec34-like family DUF4253 PF14062.6 ORZ02713.1 - 0.028 14.6 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) CLTH PF10607.9 ORZ02713.1 - 0.16 11.8 1.6 8.2 6.3 0.2 2.8 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain ATE_C PF04377.15 ORZ02714.1 - 1.2e-50 171.6 0.1 2.7e-50 170.5 0.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 ORZ02714.1 - 2.4e-26 91.9 5.0 4.4e-26 91.1 5.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus TPT PF03151.16 ORZ02716.1 - 5.7e-66 222.8 23.1 6.8e-66 222.6 23.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORZ02716.1 - 4e-16 59.4 28.9 4.8e-09 36.5 10.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORZ02716.1 - 2.3e-11 43.4 23.8 3.2e-11 43.0 23.8 1.1 1 0 0 1 1 1 1 UAA transporter family zf-BED PF02892.15 ORZ02716.1 - 0.14 12.2 1.8 0.41 10.7 1.8 1.8 1 0 0 1 1 1 0 BED zinc finger Multi_Drug_Res PF00893.19 ORZ02716.1 - 1.3 9.7 8.1 0.12 13.1 1.4 2.4 2 0 0 2 2 2 0 Small Multidrug Resistance protein PrmA PF06325.13 ORZ02717.1 - 4.2e-06 26.4 0.1 6.4e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORZ02717.1 - 1.9e-05 25.3 0.0 4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ02717.1 - 0.00027 20.8 0.0 0.00047 20.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ02717.1 - 0.0037 16.8 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORZ02717.1 - 0.04 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 ORZ02717.1 - 0.048 13.3 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DREV PF05219.12 ORZ02717.1 - 0.13 11.4 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase KDZ PF18758.1 ORZ02718.1 - 7.7e-11 42.0 4.4 1.2e-10 41.5 0.0 2.5 2 1 1 3 3 3 1 Kyakuja-Dileera-Zisupton transposase OrfB_Zn_ribbon PF07282.11 ORZ02719.1 - 8.1e-06 25.7 2.3 2.3e-05 24.2 2.3 1.7 1 1 0 1 1 1 1 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 ORZ02719.1 - 0.017 15.1 2.3 0.028 14.4 2.3 1.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF2092 PF09865.9 ORZ02719.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) DUF4005 PF13178.6 ORZ02720.1 - 0.0087 16.7 1.4 0.0087 16.7 1.4 6.0 6 0 0 6 6 6 2 Protein of unknown function (DUF4005) TPR_1 PF00515.28 ORZ02721.1 - 6.8e-12 44.7 5.5 1.7e-05 24.4 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 ORZ02721.1 - 1.1e-11 44.5 0.1 2.1e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 ORZ02721.1 - 1.9e-10 40.0 3.7 0.00051 19.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ02721.1 - 3.1e-08 34.1 8.2 8.6e-05 23.1 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ02721.1 - 2.8e-07 30.2 0.6 0.00023 21.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ02721.1 - 7.2e-06 25.6 0.0 6.2e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 TPR repeat TPR_6 PF13174.6 ORZ02721.1 - 5.4e-05 23.6 1.1 2.2 9.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ02721.1 - 0.00049 20.3 0.2 1.4 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ02721.1 - 0.0028 18.4 0.4 0.016 16.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ02721.1 - 0.0042 17.3 2.4 0.54 10.6 0.3 3.4 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ02721.1 - 0.078 13.1 0.3 0.078 13.1 0.3 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ02721.1 - 0.14 12.7 0.6 1.8 9.1 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ02721.1 - 0.18 11.9 1.0 2.5 8.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat N-SET PF11764.8 ORZ02721.1 - 4 7.5 7.6 0.82 9.8 1.5 2.6 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component N HMMR_N PF15905.5 ORZ02722.1 - 0.00031 20.3 13.9 0.00039 20.0 13.9 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 ORZ02722.1 - 0.0011 17.9 13.0 0.0014 17.6 13.0 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF948 PF06103.11 ORZ02722.1 - 0.0013 19.0 3.8 0.048 13.9 0.1 2.2 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 ORZ02722.1 - 0.0024 17.3 10.0 0.0032 16.9 10.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CCD48 PF15799.5 ORZ02722.1 - 0.0037 15.7 4.8 0.0042 15.5 4.8 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 GBP_C PF02841.14 ORZ02722.1 - 0.005 16.3 10.6 0.0062 16.0 10.6 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain RPA_interact_M PF14767.6 ORZ02722.1 - 0.0063 17.1 4.6 0.013 16.1 4.6 1.5 1 0 0 1 1 1 1 Replication protein A interacting middle Nbl1_Borealin_N PF10444.9 ORZ02722.1 - 0.0078 15.8 3.4 0.0078 15.8 3.4 2.1 3 0 0 3 3 2 1 Nbl1 / Borealin N terminal LRS4 PF10422.9 ORZ02722.1 - 0.008 15.8 9.5 0.011 15.3 9.5 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Golgin_A5 PF09787.9 ORZ02722.1 - 0.0095 15.4 12.1 0.013 15.0 12.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Atg14 PF10186.9 ORZ02722.1 - 0.014 14.5 12.7 0.021 13.9 12.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AIP3 PF03915.13 ORZ02722.1 - 0.015 14.4 9.7 0.018 14.2 9.7 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 ORZ02722.1 - 0.016 15.3 17.6 0.021 14.9 17.6 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 ORZ02722.1 - 0.02 15.4 18.2 0.051 14.1 17.0 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 ORZ02722.1 - 0.026 14.9 17.5 0.16 12.4 14.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc24 PF08286.11 ORZ02722.1 - 0.027 14.7 15.4 0.36 11.1 7.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HrpB7 PF09486.10 ORZ02722.1 - 0.036 14.4 7.3 0.058 13.8 3.6 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 ORZ02722.1 - 0.037 14.1 13.4 0.28 11.3 0.9 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Exonuc_VII_L PF02601.15 ORZ02722.1 - 0.042 13.4 6.9 0.051 13.1 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 ORZ02722.1 - 0.043 14.4 13.8 1.5 9.5 0.4 2.9 1 1 1 2 2 2 0 SlyX THOC7 PF05615.13 ORZ02722.1 - 0.043 14.1 11.3 0.062 13.6 11.3 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 MAD PF05557.13 ORZ02722.1 - 0.049 12.0 14.6 0.064 11.6 14.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF3584 PF12128.8 ORZ02722.1 - 0.072 10.6 11.0 0.093 10.2 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2228 PF10228.9 ORZ02722.1 - 0.076 12.7 4.3 0.1 12.3 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Fez1 PF06818.15 ORZ02722.1 - 0.078 13.4 14.2 0.23 11.9 14.2 1.6 1 1 0 1 1 1 0 Fez1 KxDL PF10241.9 ORZ02722.1 - 0.1 12.9 9.4 0.87 9.9 0.3 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein Filament PF00038.21 ORZ02722.1 - 0.14 11.7 14.7 0.43 10.1 14.6 1.6 1 1 0 1 1 1 0 Intermediate filament protein V_ATPase_I PF01496.19 ORZ02722.1 - 0.16 9.9 10.0 0.19 9.6 10.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 ORZ02722.1 - 0.17 12.4 16.0 0.42 11.1 7.5 2.3 2 0 0 2 2 2 0 Cell division protein ZapB TMCO5 PF14992.6 ORZ02722.1 - 0.22 11.1 16.7 0.15 11.6 1.3 2.0 1 1 1 2 2 2 0 TMCO5 family Lebercilin PF15619.6 ORZ02722.1 - 0.22 11.2 16.0 0.73 9.5 8.8 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sec2p PF06428.11 ORZ02722.1 - 0.38 10.8 14.3 0.84 9.7 1.4 2.6 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p GAS PF13851.6 ORZ02722.1 - 0.43 9.9 17.9 1.7 7.9 2.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tho2 PF11262.8 ORZ02722.1 - 0.44 9.7 6.9 0.59 9.3 6.9 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.19 ORZ02722.1 - 0.51 10.1 15.9 1.4 8.7 15.9 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 ORZ02722.1 - 0.59 10.4 15.2 0.56 10.4 8.2 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 ORZ02722.1 - 0.99 9.5 17.9 0.1 12.7 8.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 ORZ02722.1 - 1 9.7 12.2 0.91 9.9 6.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) COG2 PF06148.11 ORZ02722.1 - 1.1 9.4 9.7 1.3 9.1 3.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CorA PF01544.18 ORZ02722.1 - 1.2 8.4 9.0 1.6 8.0 9.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cnn_1N PF07989.11 ORZ02722.1 - 1.3 9.3 10.0 1.1 9.5 0.1 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 ORZ02722.1 - 1.3 9.1 23.0 3.6 7.7 11.5 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 ORZ02722.1 - 1.4 8.2 11.7 2.8 7.2 11.7 1.4 1 1 0 1 1 1 0 FAM76 protein Bap31_Bap29_C PF18035.1 ORZ02722.1 - 1.5 8.8 11.6 0.051 13.6 4.4 2.2 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FlxA PF14282.6 ORZ02722.1 - 1.7 8.7 19.5 3.3e+02 1.3 19.5 2.3 1 1 0 1 1 1 0 FlxA-like protein DUF1664 PF07889.12 ORZ02722.1 - 1.7 8.7 9.5 1.8 8.6 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 ORZ02722.1 - 1.9 7.4 15.4 4.2 6.2 15.5 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 BRE1 PF08647.11 ORZ02722.1 - 2 8.5 18.2 0.34 11.0 8.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-H PF05837.12 ORZ02722.1 - 2.1 8.8 18.2 2.7 8.4 9.2 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) LPP PF04728.13 ORZ02722.1 - 2.2 8.7 11.3 8.3 6.9 0.1 3.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper ADIP PF11559.8 ORZ02722.1 - 2.9 8.0 19.3 2.4 8.2 1.9 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 ORZ02722.1 - 3.5 8.2 13.2 17 5.9 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 ORZ02722.1 - 3.9 7.5 17.9 0.7 9.9 1.6 2.6 1 1 0 2 2 2 0 Prefoldin subunit HAUS-augmin3 PF14932.6 ORZ02722.1 - 4.4 6.8 15.3 12 5.3 15.2 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 ORZ02722.1 - 5.9 7.4 7.9 20 5.7 4.8 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 ORZ02722.1 - 6.5 6.0 17.6 16 4.7 6.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ISG65-75 PF11727.8 ORZ02722.1 - 6.5 5.9 10.9 1.3 8.2 4.1 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein Fib_alpha PF08702.10 ORZ02722.1 - 7.8 6.7 14.8 3.9 7.6 11.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 ORZ02722.1 - 7.8 6.0 13.7 4.6 6.8 7.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Phage_GP20 PF06810.11 ORZ02722.1 - 8.7 6.1 15.9 6.7 6.5 3.4 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Jnk-SapK_ap_N PF09744.9 ORZ02722.1 - 9.7 6.4 17.9 2.1 8.6 1.7 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HemX PF04375.14 ORZ02722.1 - 9.8 5.4 15.8 50 3.0 15.8 1.8 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase GRIP PF01465.20 ORZ02723.1 - 7.7e-05 22.5 0.4 0.00021 21.1 0.4 1.7 1 0 0 1 1 1 1 GRIP domain TPR_MLP1_2 PF07926.12 ORZ02723.1 - 0.0012 18.9 10.6 0.0087 16.1 1.0 2.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 ORZ02723.1 - 0.0017 18.4 7.2 0.0065 16.6 6.7 2.2 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 ORZ02723.1 - 0.0023 18.2 14.2 0.016 15.5 2.2 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 Spc7 PF08317.11 ORZ02723.1 - 0.0035 16.3 11.4 0.0046 15.9 11.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CCDC-167 PF15188.6 ORZ02723.1 - 0.0048 17.2 4.9 0.0048 17.2 4.9 2.6 1 1 2 3 3 3 1 Coiled-coil domain-containing protein 167 MbeD_MobD PF04899.12 ORZ02723.1 - 0.0093 16.1 5.2 0.031 14.4 0.4 2.4 2 0 0 2 2 2 1 MbeD/MobD like DUF2353 PF09789.9 ORZ02723.1 - 0.012 15.0 9.3 0.014 14.7 9.3 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) KfrA_N PF11740.8 ORZ02723.1 - 0.017 15.8 8.9 0.059 14.1 2.9 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Prefoldin PF02996.17 ORZ02723.1 - 0.024 14.6 2.4 0.024 14.6 2.4 2.4 2 1 0 2 2 2 0 Prefoldin subunit Cortex-I_coil PF09304.10 ORZ02723.1 - 0.024 14.8 3.2 0.024 14.8 3.2 2.3 1 1 0 2 2 2 0 Cortexillin I, coiled coil DivIC PF04977.15 ORZ02723.1 - 0.025 14.3 14.5 0.44 10.3 3.5 2.7 2 1 1 3 3 3 0 Septum formation initiator Rab_bind PF16704.5 ORZ02723.1 - 0.028 14.4 2.0 0.028 14.4 2.0 2.0 2 0 0 2 2 1 0 Rab binding domain ApoLp-III PF07464.11 ORZ02723.1 - 0.037 14.1 1.1 0.037 14.1 1.1 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) UPF0184 PF03670.13 ORZ02723.1 - 0.041 14.3 2.1 0.053 13.9 0.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) V-ATPase_H_C PF11698.8 ORZ02723.1 - 0.047 13.8 2.3 0.086 13.0 0.6 2.0 2 0 0 2 2 2 0 V-ATPase subunit H PRKG1_interact PF15898.5 ORZ02723.1 - 0.058 14.3 11.1 0.072 14.0 9.7 1.9 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Swi5 PF07061.11 ORZ02723.1 - 0.06 13.4 5.6 0.38 10.9 1.0 2.5 2 0 0 2 2 2 0 Swi5 DUF3450 PF11932.8 ORZ02723.1 - 0.078 12.3 10.1 0.92 8.8 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Yuri_gagarin PF15934.5 ORZ02723.1 - 0.09 12.6 7.0 0.12 12.2 7.0 1.1 1 0 0 1 1 1 0 Yuri gagarin DegS PF05384.11 ORZ02723.1 - 0.09 12.3 9.1 0.65 9.5 1.5 2.3 2 0 0 2 2 2 0 Sensor protein DegS Spc24 PF08286.11 ORZ02723.1 - 0.091 13.0 9.6 0.15 12.3 0.6 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 ORZ02723.1 - 0.092 12.1 3.0 0.11 11.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 ORZ02723.1 - 0.097 12.6 14.8 0.41 10.6 4.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 ORZ02723.1 - 0.1 11.2 4.0 0.15 10.6 4.0 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A GAS PF13851.6 ORZ02723.1 - 0.13 11.6 17.1 0.8 9.0 4.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CdvA PF18822.1 ORZ02723.1 - 0.14 12.0 9.3 0.17 11.7 1.5 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain RasGAP_C PF03836.15 ORZ02723.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.3 1 1 0 2 2 2 0 RasGAP C-terminus EMP24_GP25L PF01105.24 ORZ02723.1 - 0.16 11.9 3.2 1.1 9.2 0.3 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Nnf1 PF03980.14 ORZ02723.1 - 0.18 12.2 9.8 0.68 10.3 2.8 2.5 1 1 1 2 2 2 0 Nnf1 bZIP_1 PF00170.21 ORZ02723.1 - 0.18 11.9 12.0 0.25 11.5 1.2 2.8 2 1 0 2 2 2 0 bZIP transcription factor TolA_bind_tri PF16331.5 ORZ02723.1 - 0.2 11.7 12.2 1.2 9.3 0.5 3.1 3 1 0 3 3 2 0 TolA binding protein trimerisation Exonuc_VII_L PF02601.15 ORZ02723.1 - 0.25 10.9 3.2 0.29 10.7 3.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pox_A_type_inc PF04508.12 ORZ02723.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.7 3 0 0 3 3 1 0 Viral A-type inclusion protein repeat DUF4200 PF13863.6 ORZ02723.1 - 0.43 11.0 18.4 0.89 10.0 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 ORZ02723.1 - 0.49 10.9 22.7 0.36 11.4 6.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region GTP-bdg_M PF16360.5 ORZ02723.1 - 0.56 10.8 6.3 4.8 7.8 1.2 2.6 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Cep57_MT_bd PF06657.13 ORZ02723.1 - 0.71 10.4 12.8 1.8 9.1 0.7 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF5082 PF16888.5 ORZ02723.1 - 0.74 10.1 8.0 6.3 7.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF5320 PF17253.2 ORZ02723.1 - 0.81 10.8 5.5 12 7.0 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DLP_helical PF18709.1 ORZ02723.1 - 0.95 8.6 6.5 0.25 10.5 0.5 2.0 2 0 0 2 2 2 0 Dynamin-like helical domain DUF1515 PF07439.11 ORZ02723.1 - 1 9.4 2.9 1.4 9.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Phlebovirus_NSM PF07246.11 ORZ02723.1 - 1.1 8.6 4.3 7.8 5.8 0.3 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Seryl_tRNA_N PF02403.22 ORZ02723.1 - 1.1 9.5 10.5 0.46 10.7 1.9 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.9 ORZ02723.1 - 1.1 9.1 14.7 1.8 8.5 3.1 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain SlyX PF04102.12 ORZ02723.1 - 1.5 9.5 11.7 4.9 7.8 1.9 2.6 2 0 0 2 2 2 0 SlyX YabA PF06156.13 ORZ02723.1 - 1.6 9.4 11.8 4.4 8.0 0.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA HemX PF04375.14 ORZ02723.1 - 2 7.6 9.9 2.1 7.6 1.6 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 ORZ02723.1 - 2.3 8.5 11.3 4.4 7.6 1.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HAUS6_N PF14661.6 ORZ02723.1 - 2.4 7.7 10.1 1.6 8.2 0.4 2.1 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4140 PF13600.6 ORZ02723.1 - 2.7 8.5 13.7 2.1 8.8 1.5 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 ORZ02723.1 - 3.1 7.8 13.4 2.2 8.3 3.6 2.6 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 ORZ02723.1 - 3.2 7.9 8.2 11 6.2 0.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 ORZ02723.1 - 3.4 7.7 5.5 11 6.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YlqD PF11068.8 ORZ02723.1 - 3.6 8.0 10.7 1.8 8.9 1.6 2.3 2 0 0 2 2 2 0 YlqD protein Csm1_N PF18504.1 ORZ02723.1 - 5.2 7.5 11.9 8 6.9 3.0 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 ORZ02723.1 - 5.6 7.0 15.1 7.6 6.6 2.2 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.19 ORZ02723.1 - 6.4 6.4 12.5 4e+02 0.6 12.5 2.2 1 1 0 1 1 1 0 GrpE TMPIT PF07851.13 ORZ02723.1 - 6.6 5.9 6.9 9.5 5.4 2.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein XhlA PF10779.9 ORZ02723.1 - 6.7 7.0 8.3 8 6.7 1.0 2.6 3 0 0 3 3 2 0 Haemolysin XhlA FlaC_arch PF05377.11 ORZ02723.1 - 7.8 7.0 11.0 4.9 7.6 0.6 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) TIMELESS PF04821.14 ORZ02725.1 - 1.1e-63 215.1 1.9 1.1e-63 215.1 1.9 2.0 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 ORZ02725.1 - 4.8e-07 29.3 2.1 4.8e-07 29.3 2.1 2.2 2 1 0 2 2 2 1 Timeless protein C terminal region Lipase_GDSL_2 PF13472.6 ORZ02726.1 - 2.7e-09 37.7 0.0 4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORZ02726.1 - 2.6e-07 30.8 0.0 4.1e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Abhydrolase_1 PF00561.20 ORZ02727.1 - 2.2e-21 76.7 0.0 5.2e-21 75.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 ORZ02727.1 - 1.7e-15 56.3 0.0 4.7e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 ORZ02727.1 - 4.2e-06 26.2 0.0 0.00087 18.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORZ02727.1 - 4.9e-05 24.0 0.2 7.6e-05 23.4 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family KCH PF16944.5 ORZ02728.1 - 4.4e-33 115.1 0.2 7.6e-33 114.3 0.2 1.3 1 0 0 1 1 1 1 Fungal potassium channel Tho2 PF11262.8 ORZ02728.1 - 0.051 12.8 0.1 0.085 12.0 0.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Glyco_hydro_31 PF01055.26 ORZ02729.1 - 1.8e-59 202.1 0.3 2.4e-59 201.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORZ02729.1 - 0.00022 21.5 0.0 0.0038 17.5 0.0 2.7 1 1 0 1 1 1 1 Galactose mutarotase-like DUF1775 PF07987.11 ORZ02730.1 - 6.1e-38 130.4 0.8 7.2e-38 130.2 0.8 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) PEP-utilisers_N PF05524.13 ORZ02731.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal OrfB_Zn_ribbon PF07282.11 ORZ02732.1 - 0.00012 21.9 1.8 0.0018 18.1 1.8 2.1 1 1 0 1 1 1 1 Putative transposase DNA-binding domain zf-FPG_IleRS PF06827.14 ORZ02732.1 - 0.0089 15.9 6.7 0.071 13.0 0.0 3.0 2 1 0 2 2 2 1 Zinc finger found in FPG and IleRS DUF5332 PF17266.2 ORZ02732.1 - 0.025 14.3 0.2 0.07 12.8 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5332) zf_CopZ PF18423.1 ORZ02732.1 - 0.034 14.1 1.8 0.21 11.6 1.8 2.1 1 1 0 1 1 1 0 Zinc binding domain Prok-RING_1 PF14446.6 ORZ02732.1 - 0.043 13.7 1.4 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2092 PF09865.9 ORZ02732.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) UPF0547 PF10571.9 ORZ02732.1 - 1.8 8.7 6.7 0.76 9.9 0.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ACPS PF01648.20 ORZ02733.1 - 4.3e-16 59.1 0.0 5.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PGDYG PF14083.6 ORZ02733.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 PGDYG protein RhoGAP PF00620.27 ORZ02734.1 - 8.2e-33 113.4 0.0 1.9e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORZ02734.1 - 6.3e-29 100.0 46.0 2e-11 43.9 0.8 4.9 5 0 0 5 5 5 4 LIM domain zinc_ribbon_12 PF11331.8 ORZ02734.1 - 0.004 16.9 0.1 0.004 16.9 0.1 2.7 2 0 0 2 2 2 1 Probable zinc-ribbon domain FAA_hydrolase PF01557.18 ORZ02735.1 - 1.2e-57 195.2 0.0 1.4e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HMG_box PF00505.19 ORZ02736.1 - 3.8e-36 123.3 1.6 2.4e-17 63.1 0.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ02736.1 - 2.9e-27 95.0 1.8 5.1e-13 49.4 0.1 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 ORZ02736.1 - 0.0011 18.9 0.3 0.0036 17.2 0.3 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box 5 YABBY PF04690.13 ORZ02736.1 - 0.0067 17.0 2.5 0.0067 17.0 2.5 2.2 1 1 1 2 2 2 1 YABBY protein ROKNT PF08067.11 ORZ02736.1 - 5.6 7.3 5.6 1 9.7 1.0 2.2 2 0 0 2 2 2 0 ROKNT (NUC014) domain zf-C3HC4_3 PF13920.6 ORZ02737.1 - 8.1e-08 32.0 16.8 1.9e-07 30.8 16.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TSNAXIP1_N PF15739.5 ORZ02737.1 - 7.5 7.0 10.5 5.5 7.4 0.5 2.6 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus PRCC PF10253.9 ORZ02737.1 - 8.9 7.0 13.4 0.26 12.1 7.0 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting cNMP_binding PF00027.29 ORZ02738.1 - 6.5e-41 138.3 0.1 2.4e-20 72.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 ORZ02738.1 - 5.5e-09 35.5 0.9 1.1e-08 34.6 0.9 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit NOA36 PF06524.12 ORZ02738.1 - 2 7.6 4.4 3.1 7.0 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein YabA PF06156.13 ORZ02740.1 - 0.057 14.1 1.1 0.11 13.1 1.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA AATF-Che1 PF13339.6 ORZ02740.1 - 2.5 8.8 8.7 3.9 8.2 8.2 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor bZIP_2 PF07716.15 ORZ02743.1 - 0.042 13.9 0.8 0.1 12.7 0.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper YabA PF06156.13 ORZ02743.1 - 0.049 14.3 0.7 0.12 13.0 0.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 ORZ02743.1 - 0.13 12.0 0.2 0.39 10.5 0.2 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4218 PF13960.6 ORZ02744.1 - 0.00014 21.4 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RBB1NT PF08169.11 ORZ02744.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 RBB1NT (NUC162) domain SRP68 PF16969.5 ORZ02745.1 - 7.5e-109 365.2 27.5 3.2e-108 363.2 27.5 1.7 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 Ead_Ea22 PF13935.6 ORZ02745.1 - 0.8 10.4 5.5 2.6 8.7 5.5 2.1 1 1 0 1 1 1 0 Ead/Ea22-like protein RNB PF00773.19 ORZ02746.1 - 9.7e-57 192.7 0.0 2.4e-56 191.4 0.0 1.7 1 1 0 1 1 1 1 RNB domain Coprogen_oxidas PF01218.18 ORZ02747.1 - 5.9e-138 458.6 0.0 7.2e-138 458.3 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Brr6_like_C_C PF10104.9 ORZ02748.1 - 2.3e-32 111.5 1.2 3.4e-32 111.0 1.2 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Pex14_N PF04695.13 ORZ02748.1 - 0.36 11.5 7.2 0.93 10.1 7.2 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSA-2c PF12238.8 ORZ02748.1 - 2 8.4 8.2 5.6 6.9 8.2 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c PAP1 PF08601.10 ORZ02748.1 - 5.3 6.7 14.5 7.3 6.2 14.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 GTP_EFTU PF00009.27 ORZ02749.1 - 1.1e-47 162.1 0.0 1.8e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 ORZ02749.1 - 2e-25 88.7 0.0 4.8e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORZ02749.1 - 5.6e-20 71.2 0.1 8e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORZ02749.1 - 2.3e-11 43.9 0.1 6.4e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORZ02749.1 - 5.6e-08 32.7 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 ORZ02749.1 - 0.014 15.2 0.1 0.071 12.9 0.1 2.3 1 1 0 1 1 1 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 ORZ02749.1 - 0.032 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-CCHC PF00098.23 ORZ02751.1 - 7e-05 22.7 1.6 9.4e-05 22.3 1.6 1.2 1 0 0 1 1 1 1 Zinc knuckle DUF1764 PF08576.10 ORZ02752.1 - 3.6e-14 53.5 32.0 3.9e-12 46.9 23.0 3.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Nop14 PF04147.12 ORZ02752.1 - 1.3 7.1 17.6 1.3 7.1 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 ORZ02752.1 - 1.6 8.0 21.6 1.8 7.8 21.6 1.1 1 0 0 1 1 1 0 BUD22 Ndc1_Nup PF09531.10 ORZ02752.1 - 7.7 5.1 8.3 8.4 4.9 8.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SURF2 PF05477.11 ORZ02752.1 - 8.4 6.0 17.0 11 5.6 17.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NPR3 PF03666.13 ORZ02752.1 - 9.1 4.9 14.9 9 5.0 14.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAD_binding_3 PF01494.19 ORZ02753.1 - 4.5e-26 91.9 0.0 2e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ORZ02753.1 - 5.7e-09 35.5 0.9 6.9e-07 28.6 0.5 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 ORZ02753.1 - 4.2e-08 33.2 0.4 2.2e-06 27.5 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORZ02753.1 - 5.8e-07 29.0 0.0 0.0016 17.7 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORZ02753.1 - 4.3e-05 22.7 0.0 8.5e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 ORZ02753.1 - 0.00023 20.1 0.0 0.33 9.8 0.0 3.1 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 ORZ02753.1 - 0.00069 20.1 0.3 0.38 11.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORZ02753.1 - 0.00078 19.5 0.0 0.005 16.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORZ02753.1 - 0.0031 17.7 0.2 0.028 14.6 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORZ02753.1 - 0.006 15.3 0.4 0.87 8.2 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 ORZ02753.1 - 0.0081 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ORZ02753.1 - 0.018 14.2 5.2 0.39 9.7 1.0 2.2 1 1 1 2 2 2 0 FAD binding domain GIDA PF01134.22 ORZ02753.1 - 0.27 10.3 1.0 1.6 7.8 0.8 2.3 3 1 0 3 3 3 0 Glucose inhibited division protein A Porphobil_deam PF01379.20 ORZ02754.1 - 2.2e-78 262.4 0.1 3.2e-78 261.9 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ORZ02754.1 - 8.7e-19 67.7 0.2 2.1e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain cNMP_binding PF00027.29 ORZ02754.1 - 0.085 12.9 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain SMN PF06003.12 ORZ02755.1 - 4.2e-07 29.5 10.6 0.0001 21.7 1.5 3.0 1 1 2 3 3 3 2 Survival motor neuron protein (SMN) CDC45 PF02724.14 ORZ02755.1 - 0.74 8.0 12.6 0.9 7.7 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Smac_DIABLO PF09057.10 ORZ02755.1 - 1 8.7 7.5 1.5 8.1 7.5 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases RR_TM4-6 PF06459.12 ORZ02755.1 - 3.5 7.4 14.7 4.5 7.0 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 ORZ02755.1 - 3.9 7.5 4.5 4.6 7.2 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 ORZ02755.1 - 5 7.1 8.9 6.3 6.7 8.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A HSP70 PF00012.20 ORZ02755.1 - 7.4 4.6 10.3 8.6 4.4 10.3 1.2 1 0 0 1 1 1 0 Hsp70 protein Sdh5 PF03937.16 ORZ02756.1 - 4.4e-28 97.1 0.4 5.4e-28 96.8 0.4 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase P5CR_dimer PF14748.6 ORZ02757.1 - 6.7e-35 119.5 1.3 8.9e-35 119.1 0.7 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORZ02757.1 - 3.3e-21 75.7 0.3 2.1e-20 73.1 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORZ02757.1 - 0.00027 21.0 0.3 0.0018 18.3 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 ORZ02757.1 - 0.00087 19.3 0.5 0.0053 16.8 0.2 2.3 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 ORZ02757.1 - 0.0011 19.1 0.0 0.0034 17.6 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.24 ORZ02757.1 - 0.011 16.1 0.0 0.026 15.0 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_RFF PF18321.1 ORZ02757.1 - 0.025 15.0 0.2 0.074 13.5 0.1 1.9 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Sacchrp_dh_NADP PF03435.18 ORZ02757.1 - 0.05 13.9 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 ORZ02757.1 - 0.082 13.7 0.1 0.3 11.9 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 ORZ02757.1 - 0.088 12.4 1.3 1.9 8.1 1.2 2.8 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cmc1 PF08583.10 ORZ02759.1 - 9.8e-14 51.1 1.4 1.1e-13 50.9 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 ORZ02759.1 - 0.16 12.2 3.3 0.12 12.7 1.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) GCK PF07802.11 ORZ02759.1 - 0.31 11.5 3.6 0.64 10.5 3.4 1.7 1 1 0 1 1 1 0 GCK domain Lung_7-TM_R PF06814.13 ORZ02760.1 - 1.8e-36 125.9 10.6 2.3e-36 125.6 10.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 ORZ02760.1 - 0.00024 20.6 4.0 0.00024 20.6 4.0 1.7 1 1 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain adh_short PF00106.25 ORZ02761.1 - 2.8e-30 105.3 0.0 2.9e-25 88.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ02761.1 - 3.6e-19 69.3 0.0 1.6e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORZ02761.1 - 4.3e-08 33.3 0.1 7e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORZ02761.1 - 8.5e-06 25.8 0.3 1.1e-05 25.4 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORZ02761.1 - 1.1e-05 25.0 0.0 2.5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORZ02761.1 - 0.012 15.1 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 ORZ02761.1 - 0.04 13.0 0.3 0.062 12.4 0.3 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORZ02761.1 - 0.06 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.18 ORZ02762.1 - 2.2e-06 27.7 11.9 3.8e-06 26.9 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 ORZ02762.1 - 0.084 13.3 3.6 0.084 13.3 3.6 1.9 1 1 1 2 2 2 0 Potato type II proteinase inhibitor family LRR_8 PF13855.6 ORZ02763.1 - 0.026 14.3 0.4 0.38 10.5 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat Aminotran_4 PF01063.19 ORZ02764.1 - 4.8e-32 111.6 0.0 5.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Virul_fac_BrkB PF03631.15 ORZ02765.1 - 6.3e-05 22.7 8.9 9.8e-05 22.1 8.9 1.2 1 0 0 1 1 1 1 Virulence factor BrkB SARAF PF06682.12 ORZ02765.1 - 0.0006 19.6 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BaxI_1 PF12811.7 ORZ02765.1 - 0.00079 19.1 1.2 0.0011 18.6 1.2 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like MIG-14_Wnt-bd PF06664.12 ORZ02765.1 - 0.031 13.5 8.9 0.041 13.1 8.9 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Mito_fiss_reg PF05308.11 ORZ02765.1 - 0.11 12.5 3.8 0.16 12.0 3.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator 60KD_IMP PF02096.20 ORZ02765.1 - 0.29 11.0 1.5 0.45 10.4 0.6 1.7 2 0 0 2 2 2 0 60Kd inner membrane protein DUF2070 PF09843.9 ORZ02765.1 - 0.36 9.0 9.1 0.48 8.6 9.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_4_2 PF04020.13 ORZ02765.1 - 0.6 10.8 6.9 0.75 10.5 2.3 1.6 1 1 1 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV DUF5090 PF17009.5 ORZ02765.1 - 0.76 9.7 6.1 1.5 8.7 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) CopD PF05425.13 ORZ02765.1 - 1.3 9.5 6.9 0.082 13.3 1.1 2.0 2 1 0 2 2 2 0 Copper resistance protein D CAP_N PF01213.19 ORZ02765.1 - 6.1 6.2 7.2 8.6 5.7 7.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Totivirus_coat PF05518.11 ORZ02765.1 - 6.5 4.7 5.2 8.6 4.3 5.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Ras PF00071.22 ORZ02766.1 - 0.051 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Ras family DUF4500 PF14937.6 ORZ02766.1 - 0.15 12.1 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF4131 PF13567.6 ORZ02766.1 - 0.17 11.5 14.6 0.53 9.9 6.2 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) Cation_efflux PF01545.21 ORZ02766.1 - 4.7 6.9 12.4 0.07 12.9 0.6 2.8 2 1 0 2 2 2 0 Cation efflux family bZIP_1 PF00170.21 ORZ02767.1 - 1.5e-10 41.0 7.4 1.5e-10 41.0 7.4 2.2 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORZ02767.1 - 3.1e-06 27.2 8.6 3.1e-06 27.2 8.6 2.8 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORZ02767.1 - 0.00034 21.1 5.7 0.00034 21.1 5.7 2.4 3 0 0 3 3 3 1 bZIP Maf transcription factor UPF0242 PF06785.11 ORZ02767.1 - 0.0036 17.4 8.0 0.0068 16.5 3.6 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 ORZ02767.1 - 0.02 14.7 1.2 0.02 14.7 1.2 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 Ribosomal_S20p PF01649.18 ORZ02767.1 - 0.057 14.1 4.7 0.12 13.0 4.7 1.5 1 0 0 1 1 1 0 Ribosomal protein S20 DUF5355 PF17306.2 ORZ02767.1 - 0.086 11.9 0.7 0.19 10.8 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5355) DUF3450 PF11932.8 ORZ02767.1 - 0.14 11.4 4.5 0.26 10.5 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GIT_CC PF16559.5 ORZ02767.1 - 0.2 11.5 5.7 0.069 13.0 0.8 2.6 2 1 1 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4164 PF13747.6 ORZ02767.1 - 1.1 9.6 11.3 0.039 14.2 5.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4164) Asp-B-Hydro_N PF05279.11 ORZ02767.1 - 1.1 9.2 7.1 5.2 7.1 1.1 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region CCDC-167 PF15188.6 ORZ02767.1 - 1.9 8.9 13.8 2.8 8.3 6.4 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 YabA PF06156.13 ORZ02767.1 - 2.1 9.0 9.6 0.078 13.6 1.4 2.4 2 1 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 ORZ02767.1 - 2.6 7.9 9.6 0.46 10.3 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HAUS6_N PF14661.6 ORZ02767.1 - 2.7 7.5 8.7 0.19 11.3 3.5 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4140 PF13600.6 ORZ02767.1 - 7.9 7.0 6.9 2.5 8.6 2.1 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATG27 PF09451.10 ORZ02768.1 - 2.4e-46 158.7 0.0 3.1e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 ORZ02768.1 - 6.7e-05 22.1 0.3 0.00012 21.3 0.3 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 ORZ02768.1 - 0.00047 20.2 0.1 0.31 11.1 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat CDC50 PF03381.15 ORZ02769.1 - 1.2e-86 290.7 0.1 1.4e-86 290.5 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MIOX PF05153.15 ORZ02771.1 - 3.3e-101 338.0 1.0 4.1e-101 337.8 1.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD_6 PF18019.1 ORZ02771.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.5 1 1 0 1 1 1 0 HD domain HD PF01966.22 ORZ02771.1 - 0.1 12.9 0.0 1.3 9.3 0.0 2.4 1 1 0 1 1 1 0 HD domain Aldedh PF00171.22 ORZ02772.1 - 2.2e-182 606.7 0.1 2.4e-182 606.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORZ02772.1 - 0.0052 16.2 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Acetyltransf_1 PF00583.25 ORZ02774.1 - 4.5e-07 30.1 0.1 5.8e-07 29.8 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORZ02774.1 - 0.00015 22.1 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORZ02774.1 - 0.0017 18.3 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORZ02774.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein FUSC_2 PF13515.6 ORZ02775.1 - 5.6e-21 75.0 12.1 5.6e-21 75.0 12.1 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORZ02775.1 - 1.3e-12 47.1 4.7 1.3e-12 47.1 4.7 4.2 2 2 3 5 5 5 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 ORZ02775.1 - 4.3e-11 43.1 0.1 9.2e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORZ02775.1 - 3.1e-08 33.1 0.4 3.1e-08 33.1 0.4 2.3 2 1 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ORZ02775.1 - 2.1e-05 23.6 8.6 2.1e-05 23.6 8.6 2.8 2 1 1 3 3 3 1 Aluminium activated malate transporter ArAE_1 PF06081.11 ORZ02775.1 - 0.015 15.4 4.1 0.051 13.7 4.1 2.0 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 Pkinase PF00069.25 ORZ02776.1 - 7.7e-66 222.2 0.0 1.2e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02776.1 - 1.2e-27 96.9 0.1 3.7e-27 95.2 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORZ02776.1 - 0.0068 15.4 0.5 0.011 14.7 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Med13_C PF06333.12 ORZ02776.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Kdo PF06293.14 ORZ02776.1 - 0.032 13.6 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORZ02776.1 - 0.064 13.2 0.3 0.61 10.0 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family RasGAP PF00616.19 ORZ02777.1 - 9.3e-46 156.2 0.0 2.7e-45 154.7 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORZ02777.1 - 5.3e-34 117.3 0.5 5.3e-34 117.3 0.5 2.6 3 0 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 ORZ02777.1 - 9.1e-15 54.8 0.1 5.5e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 ORZ02777.1 - 2.9e-09 35.9 7.0 0.0024 17.5 0.1 5.0 5 0 0 5 5 5 3 IQ calmodulin-binding motif F-box-like PF12937.7 ORZ02778.1 - 6.4e-10 38.8 0.2 1.8e-09 37.3 0.2 1.8 1 1 0 1 1 1 1 F-box-like WD40 PF00400.32 ORZ02778.1 - 3.2e-09 37.3 4.4 0.00068 20.4 1.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.33 ORZ02778.1 - 2.3e-07 30.5 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain MltA PF03562.17 ORZ02778.1 - 0.074 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 MltA specific insert domain Herpes_U15 PF05613.11 ORZ02779.1 - 0.31 11.8 6.1 0.44 11.3 0.6 2.4 2 0 0 2 2 2 0 Human herpesvirus U15 protein Pkinase PF00069.25 ORZ02780.1 - 1.3e-63 214.8 0.0 1.6e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02780.1 - 1.1e-33 116.6 0.0 1.4e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ02780.1 - 3.9e-07 29.7 0.0 5.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 ORZ02780.1 - 0.0066 16.0 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 ORZ02780.1 - 0.0082 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORZ02780.1 - 0.0098 14.7 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORZ02780.1 - 0.049 13.6 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_transf_10 PF00852.19 ORZ02781.1 - 8.9e-48 162.3 0.0 1.2e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_trans_1_2 PF13524.6 ORZ02781.1 - 0.097 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 PB1 PF00564.24 ORZ02782.1 - 3e-07 30.3 0.3 5.6e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 PB1 domain SL4P PF17618.2 ORZ02782.1 - 0.03 14.4 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein DUF2390 PF09523.10 ORZ02782.1 - 0.2 12.0 3.6 0.43 10.9 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2390) Totivirus_coat PF05518.11 ORZ02782.1 - 8.8 4.2 14.2 11 4.0 14.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein zf-RING_2 PF13639.6 ORZ02783.1 - 9.8e-07 29.0 3.5 9.8e-07 29.0 3.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORZ02783.1 - 2.2e-06 27.9 6.0 3.5e-06 27.2 6.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORZ02783.1 - 7.2e-05 22.6 3.4 7.2e-05 22.6 3.4 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ02783.1 - 0.00025 20.9 4.9 0.00069 19.4 4.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORZ02783.1 - 0.00091 18.9 1.1 0.00091 18.9 1.1 2.3 3 0 0 3 3 2 1 RING-like zinc finger zf-RING_5 PF14634.6 ORZ02783.1 - 0.0028 17.6 8.3 0.013 15.5 8.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORZ02783.1 - 0.0056 16.7 5.2 0.011 15.7 5.2 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORZ02783.1 - 0.017 15.1 3.4 0.034 14.2 0.6 2.3 2 1 0 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORZ02783.1 - 0.025 14.2 4.0 0.025 14.2 4.0 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 ORZ02783.1 - 0.11 12.8 3.8 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SRR1 PF07985.12 ORZ02783.1 - 0.19 11.8 0.6 0.91 9.6 0.5 2.0 2 0 0 2 2 2 0 SRR1 FANCL_C PF11793.8 ORZ02783.1 - 0.24 11.6 8.0 11 6.3 8.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORZ02783.1 - 0.24 11.3 7.8 1.1 9.2 7.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 ORZ02783.1 - 0.66 10.0 4.0 2.5 8.2 4.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 ORZ02783.1 - 0.69 9.8 8.6 7.7 6.5 8.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.9 ORZ02783.1 - 1.1 9.5 5.6 6 7.1 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zf_RING PF16744.5 ORZ02783.1 - 1.3 9.1 5.2 22 5.3 2.3 2.5 2 1 0 2 2 2 0 KIAA1045 RING finger zf-UDP PF14569.6 ORZ02783.1 - 6 7.1 7.9 7.1 6.8 5.8 2.2 2 1 0 2 2 2 0 Zinc-binding RING-finger MgtE PF01769.16 ORZ02784.1 - 4.6e-46 156.2 26.6 4.1e-24 85.3 6.5 3.6 4 0 0 4 4 4 2 Divalent cation transporter Mito_carr PF00153.27 ORZ02784.1 - 0.27 11.2 3.9 1.6 8.7 0.4 3.2 2 1 0 2 2 2 0 Mitochondrial carrier protein CAGE1 PF15066.6 ORZ02785.1 - 0.016 13.9 0.1 0.018 13.7 0.1 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family SAC3 PF12209.8 ORZ02785.1 - 0.058 13.6 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain zf-C3H1 PF10650.9 ORZ02786.1 - 5.1e-09 35.7 0.4 8.3e-09 35.0 0.4 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Lysis_col PF02402.16 ORZ02786.1 - 0.33 10.7 1.1 3.5 7.4 0.8 2.4 2 1 0 2 2 2 0 Lysis protein PH_4 PF15404.6 ORZ02787.1 - 2.8e-19 69.6 5.3 1.3e-17 64.2 0.0 2.9 2 1 1 3 3 3 2 Pleckstrin homology domain PH PF00169.29 ORZ02787.1 - 2.4e-16 60.1 0.1 0.00025 21.5 0.1 4.5 4 1 0 4 4 4 3 PH domain PH_9 PF15410.6 ORZ02787.1 - 0.0052 17.2 2.8 29 5.1 0.1 4.2 4 1 0 4 4 4 2 Pleckstrin homology domain PH_2 PF08458.10 ORZ02787.1 - 0.039 14.3 0.1 5.6 7.4 0.0 2.8 2 0 0 2 2 2 0 Plant pleckstrin homology-like region ACBP PF00887.19 ORZ02788.1 - 2.7e-26 91.6 0.1 2.7e-26 91.6 0.1 2.3 2 0 0 2 2 2 1 Acyl CoA binding protein YL1 PF05764.13 ORZ02788.1 - 0.0022 18.2 21.3 0.0022 18.2 21.3 2.2 2 0 0 2 2 2 1 YL1 nuclear protein FAM176 PF14851.6 ORZ02788.1 - 0.073 12.7 14.7 0.29 10.8 4.5 3.3 3 0 0 3 3 3 0 FAM176 family MRP-S27 PF10037.9 ORZ02788.1 - 0.11 11.3 13.0 11 4.8 12.8 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 OmpH PF03938.14 ORZ02788.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) FtsH_ext PF06480.15 ORZ02788.1 - 0.79 10.1 4.7 10 6.6 0.2 2.6 2 0 0 2 2 2 0 FtsH Extracellular Importin_rep_4 PF18808.1 ORZ02788.1 - 1 9.7 4.1 0.7 10.2 1.2 2.1 2 0 0 2 2 2 0 Importin repeat CSRNP_N PF16019.5 ORZ02788.1 - 2.2 8.2 18.9 0.84 9.5 1.8 3.0 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus TCO89 PF10452.9 ORZ02789.1 - 5.7e-11 42.1 0.1 5.7e-11 42.1 0.1 1.7 2 0 0 2 2 2 1 TORC1 subunit TCO89 SR-25 PF10500.9 ORZ02789.1 - 1.4 8.4 6.7 2.2 7.9 6.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 ORZ02790.1 - 4.3e-39 131.8 18.1 1.2e-07 32.3 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ02790.1 - 9.4e-13 48.3 0.1 0.012 15.9 0.1 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ02790.1 - 0.00027 20.4 0.0 0.23 10.8 0.0 3.5 3 1 1 4 4 4 2 WD40-like domain eIF2A PF08662.11 ORZ02790.1 - 0.02 14.8 0.0 2.2 8.1 0.0 2.3 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Phage_GP20 PF06810.11 ORZ02790.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Glyco_hydro_17 PF00332.18 ORZ02791.1 - 7.8e-13 48.7 4.4 1.3e-09 38.1 0.5 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 SGS PF05002.15 ORZ02792.1 - 0.011 15.9 0.3 0.078 13.1 0.1 2.3 2 1 0 2 2 2 0 SGS domain Rib PF08428.10 ORZ02792.1 - 0.043 13.8 0.9 0.067 13.2 0.2 1.7 2 0 0 2 2 2 0 Rib/alpha-like repeat zf-C2H2_2 PF12756.7 ORZ02793.1 - 1.8e-33 114.9 12.4 1.3e-27 96.1 0.2 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORZ02793.1 - 1e-07 32.1 5.9 1.3e-07 31.7 2.6 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORZ02793.1 - 1.3e-07 31.7 15.7 2.9e-06 27.4 3.4 3.1 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORZ02793.1 - 0.00018 22.1 14.2 0.29 12.1 0.3 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger AKAP95 PF04988.12 ORZ02793.1 - 0.016 15.4 2.1 0.39 10.9 0.5 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF1644 PF07800.12 ORZ02793.1 - 0.074 13.1 3.3 0.44 10.6 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) BIR PF00653.21 ORZ02793.1 - 0.12 13.0 7.6 1.1 10.0 0.1 3.8 2 1 2 4 4 4 0 Inhibitor of Apoptosis domain zf-C2H2 PF00096.26 ORZ02793.1 - 0.14 12.7 19.2 1.1 9.9 0.9 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Cytochrome_C7 PF14522.6 ORZ02793.1 - 0.44 10.6 10.0 16 5.6 6.2 2.9 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zf-C2H2_3rep PF18868.1 ORZ02793.1 - 2.2 9.0 9.1 2.2 8.9 2.3 3.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 ORZ02793.1 - 4.3 7.5 9.2 1.1 9.3 0.9 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger DUF1178 PF06676.11 ORZ02793.1 - 4.3 7.7 8.6 0.4 11.1 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Peptidase_M49 PF03571.15 ORZ02794.1 - 8.8e-08 31.0 0.2 3.7e-06 25.6 0.0 2.6 1 1 1 2 2 2 2 Peptidase family M49 MPTase-PolyVal PF18818.1 ORZ02794.1 - 0.002 18.2 0.8 0.0043 17.1 0.2 1.9 2 0 0 2 2 2 1 Metallopeptidase superfamily domain Atg14 PF10186.9 ORZ02795.1 - 3.1e-11 43.0 20.5 2e-09 37.0 17.0 2.6 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 ORZ02795.1 - 8.9e-09 34.7 3.8 3.6e-08 32.7 0.9 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting 38 C2 PF00168.30 ORZ02795.1 - 0.036 14.3 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 C2 domain Exonuc_VII_L PF02601.15 ORZ02795.1 - 0.17 11.4 7.5 0.3 10.6 7.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_N PF10481.9 ORZ02795.1 - 0.33 10.6 12.5 0.017 14.8 6.1 2.0 2 0 0 2 2 2 0 Cenp-F N-terminal domain Spc7 PF08317.11 ORZ02795.1 - 0.33 9.8 13.2 0.49 9.2 13.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1204 PF06721.11 ORZ02795.1 - 2.3 7.6 11.7 2.8 7.3 10.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) zf-C4H2 PF10146.9 ORZ02795.1 - 2.9 8.2 10.5 4.5 7.5 8.2 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein SOCS PF12610.8 ORZ02795.1 - 5 7.6 7.1 0.85 10.1 0.6 2.9 3 0 0 3 3 3 0 Suppressor of cytokine signalling Rotamase_3 PF13616.6 ORZ02796.1 - 2.5e-17 63.5 0.2 1.2e-16 61.2 0.2 2.1 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ORZ02796.1 - 1.8e-15 57.6 0.5 7.6e-15 55.6 0.5 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ORZ02796.1 - 0.00091 20.1 1.5 0.0054 17.6 1.5 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Mucin PF01456.17 ORZ02797.1 - 0.016 15.2 1.1 0.016 15.2 1.1 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF4094 PF13334.6 ORZ02797.1 - 0.028 14.8 1.1 0.028 14.8 1.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) SIR2 PF02146.17 ORZ02799.1 - 1.5e-61 207.4 0.0 2.1e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 ORZ02799.1 - 3.5e-05 23.6 1.3 7.6e-05 22.5 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 ORZ02799.1 - 0.028 14.1 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CutC PF03932.14 ORZ02799.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 CutC family Ank_4 PF13637.6 ORZ02800.1 - 1.7e-14 53.9 1.2 2.9e-07 30.9 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORZ02800.1 - 5.8e-14 52.4 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORZ02800.1 - 1.1e-10 41.5 0.7 3.3e-07 30.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORZ02800.1 - 3.4e-09 36.8 0.3 1.8e-08 34.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ02800.1 - 1.3e-07 31.3 0.0 3.8e-06 26.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Glyco_trans_1_3 PF13528.6 ORZ02800.1 - 0.17 11.1 0.3 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 1 Oxidored_FMN PF00724.20 ORZ02802.1 - 8e-106 354.1 0.0 9.2e-106 353.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RTC4 PF14474.6 ORZ02803.1 - 4.8e-25 88.1 0.0 1.5e-24 86.4 0.0 1.9 1 0 0 1 1 1 1 RTC4-like domain Nucleos_tra2_C PF07662.13 ORZ02804.1 - 1.3e-73 247.3 9.3 1.3e-73 247.3 9.3 3.0 2 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORZ02804.1 - 6.2e-19 68.4 6.4 6.2e-19 68.4 6.4 3.8 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Sec2p PF06428.11 ORZ02805.1 - 8.6e-11 41.7 15.8 8.6e-11 41.7 15.8 2.7 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 ORZ02805.1 - 4.1e-07 30.4 14.9 4.1e-07 30.4 14.9 3.3 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) Bac_DnaA PF00308.18 ORZ02805.1 - 0.0026 17.6 3.1 0.0044 16.9 3.1 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein PAP1 PF08601.10 ORZ02805.1 - 0.0048 16.7 8.9 0.015 15.1 8.9 1.8 1 0 0 1 1 1 1 Transcription factor PAP1 TACC_C PF05010.14 ORZ02805.1 - 0.073 12.9 14.2 0.23 11.2 14.2 1.8 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF5401 PF17380.2 ORZ02805.1 - 0.18 9.8 8.8 0.36 8.9 8.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF2018 PF09442.10 ORZ02805.1 - 0.93 10.5 6.2 29 5.7 5.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2018) Glyco_hydro_2 PF00703.21 ORZ02805.1 - 2.4 8.9 5.9 8.3 7.1 0.1 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 2 Exonuc_VII_L PF02601.15 ORZ02805.1 - 4 6.9 19.6 0.6 9.6 11.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit APG6_N PF17675.1 ORZ02805.1 - 6.7 7.2 36.8 2.1 8.9 25.9 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region Amelogenin PF02948.15 ORZ02806.1 - 0.56 10.8 6.1 0.81 10.3 3.7 1.9 1 1 1 2 2 2 0 Amelogenin Pkinase PF00069.25 ORZ02807.1 - 5.9e-61 206.1 0.0 2e-39 135.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02807.1 - 4.3e-28 98.3 0.0 3.1e-21 75.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 ORZ02807.1 - 6.4e-15 55.3 1.3 1.3e-14 54.3 0.4 2.1 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.6 ORZ02807.1 - 0.00024 20.5 0.1 0.014 14.8 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORZ02807.1 - 0.00067 19.6 1.0 0.042 13.8 0.1 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORZ02807.1 - 0.0086 15.1 0.0 0.0086 15.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORZ02807.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MT-A70 PF05063.14 ORZ02808.1 - 4.3e-06 26.8 0.0 5.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 MT-A70 Myb_DNA-binding PF00249.31 ORZ02810.1 - 0.017 15.3 0.3 0.017 15.3 0.3 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain MBF1 PF08523.10 ORZ02811.1 - 1.8e-19 69.9 11.0 1.9e-19 69.9 7.3 2.5 2 2 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 ORZ02811.1 - 7e-16 58.0 0.3 1.2e-15 57.3 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ORZ02811.1 - 1.4e-07 31.7 0.1 3.9e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 ORZ02811.1 - 1.1e-05 25.4 0.1 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ORZ02811.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 ORZ02811.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain KptA_kDCL PF18176.1 ORZ02811.1 - 0.13 12.1 0.5 0.23 11.3 0.3 1.4 1 1 0 1 1 1 0 KptA in kinetoplastid DICER domain HTH_26 PF13443.6 ORZ02811.1 - 0.15 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain ABC2_membrane PF01061.24 ORZ02812.1 - 1.2e-75 253.5 63.5 1.9e-41 141.8 22.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORZ02812.1 - 1.2e-39 136.0 0.0 4.9e-21 75.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORZ02812.1 - 2.9e-27 94.4 0.1 4.6e-21 74.5 0.0 3.7 4 1 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORZ02812.1 - 9.7e-12 45.4 0.0 2.1e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 ORZ02812.1 - 6.2e-07 29.5 0.2 0.0017 18.2 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORZ02812.1 - 2.2e-06 28.2 0.0 0.0014 19.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 ORZ02812.1 - 1.8e-05 24.0 9.7 1.8e-05 24.0 9.7 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORZ02812.1 - 0.00017 21.5 0.8 0.007 16.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORZ02812.1 - 0.00037 20.2 0.4 0.019 14.7 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORZ02812.1 - 0.0053 17.3 0.0 0.067 13.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 ORZ02812.1 - 0.0095 15.5 0.1 0.032 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORZ02812.1 - 0.011 15.9 0.2 0.85 9.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 ORZ02812.1 - 0.039 14.2 0.1 1 9.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 ORZ02812.1 - 0.042 13.9 0.2 10 6.2 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 ORZ02812.1 - 0.14 11.8 0.3 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORZ02812.1 - 0.15 12.3 0.1 0.76 10.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 ORZ02812.1 - 0.23 11.9 0.0 0.55 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TMEM251 PF15190.6 ORZ02812.1 - 0.87 9.6 5.1 0.4 10.6 1.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 251 ABC2_membrane_2 PF12679.7 ORZ02812.1 - 3 7.0 11.4 0.12 11.6 1.3 2.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Methyltr_RsmB-F PF01189.17 ORZ02813.1 - 7e-29 100.9 0.0 3.9e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 ORZ02813.1 - 3.2e-07 31.0 0.1 6.9e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ02813.1 - 4.2e-05 23.4 0.0 0.0004 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ02813.1 - 0.00077 20.1 0.0 0.13 12.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DUF4568 PF15132.6 ORZ02813.1 - 0.0036 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4568) FtsJ PF01728.19 ORZ02813.1 - 0.0045 17.1 0.0 0.0071 16.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 ORZ02813.1 - 0.094 12.3 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.6 ORZ02813.1 - 0.14 11.9 0.0 6.2 6.6 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Sec66 PF09802.9 ORZ02814.1 - 2.9e-41 141.0 5.8 3.5e-41 140.7 5.8 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 RE_Bpu10I PF09549.10 ORZ02814.1 - 0.022 14.3 0.7 0.35 10.4 0.1 2.1 2 0 0 2 2 2 0 Bpu10I restriction endonuclease CCDC84 PF14968.6 ORZ02814.1 - 0.11 12.0 8.0 0.18 11.4 8.0 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 SieB PF14163.6 ORZ02814.1 - 0.36 10.3 0.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B CBFD_NFYB_HMF PF00808.23 ORZ02815.1 - 0.086 13.1 0.2 3.6 8.0 0.0 2.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LRR_8 PF13855.6 ORZ02816.1 - 2.5e-09 36.8 17.2 6.7e-06 25.8 4.7 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORZ02816.1 - 2.9e-06 27.5 5.9 0.00014 22.2 4.7 2.7 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORZ02816.1 - 0.48 11.2 4.5 20 6.2 0.3 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_3 PF07725.12 ORZ02816.1 - 6.1 6.9 5.4 8.5 6.4 1.3 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat PAP2 PF01569.21 ORZ02817.1 - 1.4e-21 76.7 5.4 4.2e-21 75.1 5.4 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ORZ02817.1 - 0.0048 16.6 9.1 0.014 15.1 9.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 ORZ02817.1 - 0.22 12.1 11.2 0.057 14.0 5.0 2.7 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF3425 PF11905.8 ORZ02818.1 - 4.2e-09 36.4 0.0 1.7e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3425 PF11905.8 ORZ02819.1 - 1.9e-12 47.2 0.8 8.5e-12 45.1 0.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORZ02819.1 - 4.5e-06 26.7 6.6 1e-05 25.5 6.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF4407 PF14362.6 ORZ02819.1 - 0.034 13.5 0.1 0.034 13.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5094 PF17015.5 ORZ02819.1 - 0.06 13.5 0.2 0.06 13.5 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) DUF4140 PF13600.6 ORZ02819.1 - 1.5 9.3 12.0 1.5 9.3 2.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CFIA_Pcf11 PF11526.8 ORZ02819.1 - 1.5 9.3 15.6 0.059 13.9 4.9 3.1 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 RR_TM4-6 PF06459.12 ORZ02819.1 - 3.8 7.2 14.1 8.5 6.1 9.5 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Roughex PF06020.11 ORZ02819.1 - 5.3 6.0 10.2 8.9 5.3 10.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 ORZ02819.1 - 8.5 4.4 9.5 13 3.7 9.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Kei1 PF08552.11 ORZ02819.1 - 9.7 6.0 6.2 4.2 7.2 3.0 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 C2 PF00168.30 ORZ02820.1 - 1.2e-09 38.3 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain Ran_BP1 PF00638.18 ORZ02821.1 - 1.9e-53 179.9 2.5 3.5e-53 179.0 2.5 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 ORZ02821.1 - 1.1e-05 25.4 0.7 7.8e-05 22.6 0.7 2.1 1 1 0 1 1 1 1 WH1 domain LPD25 PF18840.1 ORZ02821.1 - 1.6 9.3 10.6 17 6.1 0.2 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 25 DAO PF01266.24 ORZ02823.1 - 1.6e-31 110.2 0.2 1.9e-31 110.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 ORZ02823.1 - 0.00036 20.1 0.0 0.038 13.5 0.0 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 ORZ02823.1 - 0.036 13.3 0.0 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORZ02823.1 - 0.056 12.7 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORZ02823.1 - 0.057 13.7 0.1 0.27 11.5 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 ORZ02823.1 - 0.13 11.9 0.7 0.21 11.1 0.7 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 ORZ02823.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NIR_SIR_ferr PF03460.17 ORZ02823.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain FAD_oxidored PF12831.7 ORZ02823.1 - 0.17 11.2 0.1 0.59 9.4 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORZ02823.1 - 0.21 12.1 0.3 0.46 11.1 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SPX PF03105.19 ORZ02824.1 - 0.082 12.8 0.6 0.1 12.5 0.6 1.0 1 0 0 1 1 1 0 SPX domain Peptidase_C11 PF03415.14 ORZ02824.1 - 0.21 10.9 0.1 0.26 10.7 0.1 1.1 1 0 0 1 1 1 0 Clostripain family FAM72 PF14976.6 ORZ02825.1 - 1.5e-37 128.9 7.0 1.9e-37 128.6 7.0 1.2 1 0 0 1 1 1 1 FAM72 protein Pkinase PF00069.25 ORZ02827.1 - 1.4e-13 50.8 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 ORZ02827.1 - 5e-08 32.6 0.0 7.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 ORZ02827.1 - 0.0029 17.0 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.13 ORZ02827.1 - 0.0062 15.4 0.3 0.0098 14.8 0.3 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Yip1 PF04893.17 ORZ02827.1 - 0.028 14.1 0.0 0.23 11.2 0.0 2.3 3 0 0 3 3 3 0 Yip1 domain Podoplanin PF05808.11 ORZ02827.1 - 5.2 7.1 7.6 38 4.4 7.6 2.2 1 1 0 1 1 1 0 Podoplanin F-box-like PF12937.7 ORZ02828.1 - 1.6e-08 34.3 1.4 4.6e-08 32.8 1.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ02828.1 - 9.5e-07 28.5 0.3 9.5e-07 28.5 0.3 2.8 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 ORZ02828.1 - 0.01 15.7 0.1 0.039 13.8 0.0 2.1 2 1 0 2 2 2 0 F-box LRR_4 PF12799.7 ORZ02828.1 - 0.021 15.2 1.5 2.4 8.7 0.1 3.9 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 ORZ02828.1 - 0.066 13.9 0.6 0.58 10.9 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat Lum_binding PF00677.17 ORZ02829.1 - 3.2e-46 155.2 0.6 5.6e-23 80.7 0.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain PDZ_5 PF17817.1 ORZ02830.1 - 0.0045 17.2 2.2 0.0093 16.2 0.0 2.4 2 1 1 3 3 3 1 PDZ domain AGTRAP PF06396.11 ORZ02831.1 - 3.1e-10 40.1 0.0 3.7e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) HTH_23 PF13384.6 ORZ02833.1 - 6.3e-05 22.7 0.1 0.00017 21.3 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 ORZ02833.1 - 0.00022 21.2 0.0 0.00087 19.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 ORZ02833.1 - 0.0015 18.6 0.2 0.0067 16.5 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_8 PF02954.19 ORZ02833.1 - 0.0062 16.3 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_Tnp_1 PF01527.20 ORZ02833.1 - 0.0085 16.4 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 Transposase DUF3768 PF12599.8 ORZ02833.1 - 0.035 14.1 0.4 11 6.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3768) RR_TM4-6 PF06459.12 ORZ02833.1 - 0.45 10.3 3.7 0.64 9.8 3.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_P_Rpp14 PF01900.19 ORZ02835.1 - 7.9e-22 77.4 0.0 1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ALG3 PF05208.13 ORZ02836.1 - 4.6e-99 332.2 11.4 5.5e-99 332.0 11.4 1.0 1 0 0 1 1 1 1 ALG3 protein zf-C2H2 PF00096.26 ORZ02837.1 - 7.3e-08 32.5 5.5 0.0005 20.4 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ02837.1 - 6e-07 29.8 4.8 0.013 16.3 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORZ02837.1 - 0.0061 16.5 4.6 0.11 12.5 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ02837.1 - 0.011 16.3 1.6 0.23 12.1 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORZ02837.1 - 0.022 15.0 0.9 0.16 12.3 0.9 2.2 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 ORZ02837.1 - 0.13 11.9 0.6 0.26 11.0 0.1 1.6 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Ndc1_Nup PF09531.10 ORZ02837.1 - 1 8.0 9.4 1.4 7.6 9.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3676 PF12429.8 ORZ02838.1 - 0.038 13.8 0.3 0.038 13.8 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3676) Glyco_transf_7C PF02709.14 ORZ02838.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase TssO PF17561.2 ORZ02839.1 - 0.19 11.8 0.8 0.21 11.7 0.8 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF1218 PF06749.12 ORZ02840.1 - 9.4 6.8 11.1 1.6 9.3 1.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Cortexin PF11057.8 ORZ02841.1 - 0.38 10.6 2.4 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Cortexin of kidney MRP-L28 PF09812.9 ORZ02842.1 - 3.8e-17 62.9 4.5 5.5e-17 62.4 4.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Halogen_Hydrol PF10112.9 ORZ02843.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PRCC PF10253.9 ORZ02844.1 - 0.17 12.7 5.4 0.21 12.4 5.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Nucleo_P87 PF07267.11 ORZ02844.1 - 4.2 6.1 6.0 4.8 5.9 6.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SR-25 PF10500.9 ORZ02844.1 - 6.4 6.3 11.5 0.024 14.3 2.1 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Stevor PF17410.2 ORZ02845.1 - 0.00081 19.0 0.1 0.0025 17.4 0.1 1.8 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4690 PF15756.5 ORZ02845.1 - 0.96 10.1 5.6 0.35 11.5 0.4 3.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage GATA PF00320.27 ORZ02847.1 - 0.0024 17.4 8.1 0.0024 17.4 8.1 3.2 2 1 0 2 2 2 1 GATA zinc finger DZR PF12773.7 ORZ02847.1 - 5.4 7.1 11.2 0.49 10.5 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon CLASP_N PF12348.8 ORZ02848.1 - 9.3e-28 97.3 0.4 7.9e-07 28.9 0.0 5.9 5 1 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 ORZ02848.1 - 1.3e-13 49.9 11.8 0.81 10.1 0.0 11.0 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 ORZ02848.1 - 1.5e-13 50.9 18.2 0.0097 16.3 0.3 8.8 9 1 1 10 10 10 4 HEAT repeats Cnd1 PF12717.7 ORZ02848.1 - 9.1e-12 45.3 2.4 0.24 11.4 0.0 7.8 7 1 1 8 8 8 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORZ02848.1 - 2e-08 34.7 0.0 1.9 9.1 0.0 6.4 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORZ02848.1 - 6.1e-05 23.4 17.1 4.5 7.9 0.0 7.6 7 1 0 7 7 7 2 HEAT-like repeat MMS19_N PF14500.6 ORZ02848.1 - 0.017 14.7 0.9 1 8.9 0.0 4.4 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Fasciclin PF02469.22 ORZ02849.1 - 1.2e-73 245.4 0.0 3.1e-20 72.7 0.2 5.3 5 0 0 5 5 5 5 Fasciclin domain NDUF_B12 PF08122.12 ORZ02850.1 - 2.8e-23 81.7 0.9 3.2e-23 81.5 0.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family HSP70 PF00012.20 ORZ02851.1 - 1.9e-261 868.5 12.4 2.2e-261 868.3 12.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORZ02851.1 - 4.1e-14 52.2 4.0 5.4e-12 45.2 1.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 ORZ02851.1 - 0.00028 20.7 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DHHA1 PF02272.19 ORZ02851.1 - 0.054 13.9 1.4 0.31 11.5 1.4 2.3 1 0 0 1 1 1 0 DHHA1 domain FtsA PF14450.6 ORZ02851.1 - 0.067 13.6 11.4 1.5 9.3 0.2 4.3 3 3 0 3 3 3 0 Cell division protein FtsA DUF5486 PF17588.2 ORZ02851.1 - 0.43 10.5 1.4 6.3 6.8 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Radical_SAM PF04055.21 ORZ02852.1 - 3.3e-11 43.9 0.0 7.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 ORZ02852.1 - 4e-06 26.8 0.1 4.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 HemN C-terminal domain GGDEF_2 PF17853.1 ORZ02852.1 - 0.1 12.8 0.6 0.4 10.9 0.1 2.1 3 0 0 3 3 3 0 GGDEF-like domain DEAD PF00270.29 ORZ02853.1 - 1.1e-44 152.3 0.1 1.5e-44 151.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ02853.1 - 4.9e-28 97.7 1.3 7e-27 94.0 0.4 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ02853.1 - 6.6e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORZ02853.1 - 0.038 13.3 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NAGidase PF07555.13 ORZ02853.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase UvrD-helicase PF00580.21 ORZ02853.1 - 0.14 11.6 1.0 0.21 11.1 0.1 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain tRNA-synt_2b PF00587.25 ORZ02854.1 - 2.9e-42 144.7 0.0 4.7e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORZ02854.1 - 2.1e-13 50.2 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.6 ORZ02854.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Mitoc_L55 PF09776.9 ORZ02854.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 AAA PF00004.29 ORZ02855.1 - 4.6e-18 65.9 0.0 1e-17 64.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORZ02855.1 - 9.5e-17 61.2 0.1 1.6e-15 57.2 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 ORZ02855.1 - 1.2e-12 48.0 0.3 3.4e-12 46.6 0.3 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 ORZ02855.1 - 1e-08 35.3 0.0 2.2e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 ORZ02855.1 - 1.3e-06 28.3 0.0 4.9e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORZ02855.1 - 1.6e-05 25.2 0.0 0.00071 19.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORZ02855.1 - 1.8e-05 24.7 0.2 2.9e-05 24.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ02855.1 - 4.1e-05 24.0 0.1 0.00067 20.1 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 ORZ02855.1 - 5.8e-05 22.6 0.0 0.0021 17.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORZ02855.1 - 8.3e-05 22.6 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ORZ02855.1 - 9e-05 22.5 0.0 0.0011 19.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 ORZ02855.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 ORZ02855.1 - 0.00023 21.4 0.1 0.0023 18.2 0.0 2.6 3 0 0 3 3 3 1 AAA C-terminal domain DUF815 PF05673.13 ORZ02855.1 - 0.00042 19.6 0.0 0.00067 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 ORZ02855.1 - 0.00045 20.0 0.0 0.00087 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORZ02855.1 - 0.0006 19.2 0.0 0.0017 17.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.13 ORZ02855.1 - 0.00086 19.1 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 ORZ02855.1 - 0.002 18.5 0.1 0.029 14.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ORZ02855.1 - 0.0037 17.2 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 ORZ02855.1 - 0.0061 16.6 0.0 0.031 14.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORZ02855.1 - 0.0089 15.9 0.0 0.034 14.0 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORZ02855.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MecA_N PF05223.11 ORZ02855.1 - 0.018 15.3 0.3 0.047 14.0 0.1 1.9 2 0 0 2 2 1 0 NTF2-like N-terminal transpeptidase domain AAA_18 PF13238.6 ORZ02855.1 - 0.023 15.2 0.0 0.054 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORZ02855.1 - 0.024 14.4 0.0 0.051 13.3 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 ORZ02855.1 - 0.026 14.0 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein RsgA_GTPase PF03193.16 ORZ02855.1 - 0.028 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 ORZ02855.1 - 0.038 14.5 0.1 0.059 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 ORZ02855.1 - 0.043 13.6 0.2 0.56 9.9 0.2 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_28 PF13521.6 ORZ02855.1 - 0.053 13.8 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORZ02855.1 - 0.057 13.8 0.2 0.18 12.2 0.0 2.1 2 1 0 2 2 1 0 RNA helicase Nuc_deoxyri_tr3 PF11071.8 ORZ02855.1 - 0.058 13.5 0.4 0.28 11.2 0.1 2.2 3 0 0 3 3 2 0 Nucleoside 2-deoxyribosyltransferase YtoQ ANTH PF07651.16 ORZ02856.1 - 1.9e-70 237.0 0.0 1.9e-70 237.0 0.0 3.9 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 ORZ02856.1 - 5.9e-53 179.2 14.2 5.9e-53 179.2 14.2 6.5 4 2 2 6 6 6 1 I/LWEQ domain RACo_linker PF17650.1 ORZ02856.1 - 10 6.1 13.9 13 5.7 0.6 4.6 5 0 0 5 5 5 0 RACo linker region KIF1B PF12423.8 ORZ02857.1 - 1.4 9.5 4.0 18 5.9 0.4 2.8 2 0 0 2 2 2 0 Kinesin protein 1B HMA PF00403.26 ORZ02858.1 - 2e-17 63.4 0.4 2.2e-17 63.2 0.4 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain ThiS PF02597.20 ORZ02859.1 - 6.8e-18 65.1 0.2 7.6e-18 64.9 0.2 1.0 1 0 0 1 1 1 1 ThiS family Lambda_tail_I PF06805.12 ORZ02859.1 - 0.017 15.4 0.0 0.018 15.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I GTP_cyclohydro2 PF00925.20 ORZ02860.1 - 4.3e-65 218.3 0.0 7.6e-65 217.5 0.0 1.4 1 1 0 1 1 1 1 GTP cyclohydrolase II AMP-binding PF00501.28 ORZ02861.1 - 3.9e-75 253.1 0.0 4.8e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ02861.1 - 6.6e-12 46.2 0.1 1.6e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AJAP1_PANP_C PF15298.6 ORZ02861.1 - 0.021 15.0 0.2 0.038 14.2 0.2 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus AMP-binding PF00501.28 ORZ02862.1 - 2.8e-67 227.1 0.0 3.3e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ02862.1 - 4.3e-09 37.2 0.0 7.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CTP_transf_1 PF01148.20 ORZ02863.1 - 4.4e-73 246.3 20.3 5.7e-73 245.9 20.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SAE2 PF08573.10 ORZ02864.1 - 1.7e-09 38.8 18.2 1.3e-07 32.7 0.6 3.5 2 2 2 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus CheY-binding PF09078.11 ORZ02864.1 - 0.2 11.8 1.4 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 CheY binding DUF3584 PF12128.8 ORZ02864.1 - 0.56 7.7 8.2 0.68 7.4 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) p450 PF00067.22 ORZ02865.1 - 3.9e-76 256.7 0.2 5e-76 256.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 BLIP PF07467.11 ORZ02865.1 - 0.15 12.6 0.0 0.39 11.3 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) Ribonuc_L-PSP PF01042.21 ORZ02866.1 - 2.2e-44 150.4 0.1 2.4e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sterol_MT_C PF08498.10 ORZ02867.1 - 1.2e-21 76.7 0.1 2.1e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ORZ02867.1 - 4e-19 69.0 0.1 1.1e-18 67.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ02867.1 - 1.9e-17 63.8 0.0 5e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ02867.1 - 2.8e-17 62.9 0.0 4.9e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORZ02867.1 - 2e-12 47.0 0.0 2.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORZ02867.1 - 1e-09 38.5 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ02867.1 - 4.5e-09 36.0 0.0 7.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORZ02867.1 - 5.5e-08 33.5 0.0 3.6e-07 30.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain MetW PF07021.12 ORZ02867.1 - 0.0007 19.2 0.0 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 ORZ02867.1 - 0.00093 18.8 0.0 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORZ02867.1 - 0.0051 16.1 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_15 PF09445.10 ORZ02867.1 - 0.0061 16.1 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 ORZ02867.1 - 0.055 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FtsJ PF01728.19 ORZ02867.1 - 0.062 13.4 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 ORZ02867.1 - 0.064 13.2 0.2 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 ORZ02867.1 - 0.09 12.5 0.2 0.17 11.6 0.2 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 ORZ02867.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.9 2 1 0 2 2 1 0 Hypothetical methyltransferase WW PF00397.26 ORZ02868.1 - 3.6e-08 33.4 0.7 7.5e-08 32.3 0.7 1.6 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 ORZ02868.1 - 0.013 15.8 0.2 0.029 14.6 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain Macoilin PF09726.9 ORZ02868.1 - 1.6 7.2 11.1 2.3 6.7 11.1 1.1 1 0 0 1 1 1 0 Macoilin family RhoGAP PF00620.27 ORZ02870.1 - 1.4e-40 138.6 0.0 3e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORZ02870.1 - 3.1e-14 53.4 0.0 5.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORZ02870.1 - 7.2e-06 26.4 0.0 2.3e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.24 ORZ02870.1 - 7.1e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 ORZ02870.1 - 0.014 15.7 0.0 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1952 PF09189.10 ORZ02870.1 - 0.2 11.5 0.0 0.48 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) BBS1 PF14779.6 ORZ02870.1 - 1.4 8.3 4.2 0.38 10.2 0.5 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Ysc84 PF04366.12 ORZ02871.1 - 1.1e-43 148.1 0.4 1.9e-43 147.3 0.4 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORZ02871.1 - 3.5e-15 55.3 0.1 6.4e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORZ02871.1 - 2e-13 49.8 0.0 4.7e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORZ02871.1 - 1.7e-12 47.0 0.0 3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SCP2 PF02036.17 ORZ02872.1 - 2e-05 25.0 0.0 2.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family U79_P34 PF03064.16 ORZ02872.1 - 0.082 12.3 0.2 0.26 10.6 0.0 1.6 1 1 1 2 2 2 0 HSV U79 / HCMV P34 Iwr1 PF08574.10 ORZ02873.1 - 5.4e-11 43.3 24.6 5.4e-11 43.3 24.6 3.1 4 1 0 4 4 4 1 Transcription factor Iwr1 TAFII55_N PF04658.13 ORZ02873.1 - 0.0006 19.6 0.6 0.0017 18.1 0.3 2.0 1 1 1 2 2 2 1 TAFII55 protein conserved region Med9 PF07544.13 ORZ02873.1 - 0.0073 16.4 2.6 0.076 13.1 0.8 2.4 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 RhoGAP PF00620.27 ORZ02874.1 - 3.6e-34 117.8 0.0 8.6e-34 116.6 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain Ribosomal_L29 PF00831.23 ORZ02875.1 - 1.4e-15 57.0 4.9 1.4e-15 57.0 4.9 2.4 1 1 1 2 2 2 1 Ribosomal L29 protein ANTH PF07651.16 ORZ02876.1 - 9.1e-76 254.5 0.1 9.1e-76 254.5 0.1 3.6 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 ORZ02876.1 - 2.1e-53 180.7 11.8 2.1e-53 180.7 11.8 5.2 3 1 1 4 4 4 2 I/LWEQ domain ENTH PF01417.20 ORZ02876.1 - 3e-05 24.1 0.1 3e-05 24.1 0.1 2.9 2 1 0 2 2 2 1 ENTH domain Spc7 PF08317.11 ORZ02876.1 - 0.00099 18.1 21.6 0.00099 18.1 21.6 5.2 3 1 2 5 5 5 2 Spc7 kinetochore protein RICTOR_M PF14666.6 ORZ02876.1 - 0.0081 15.9 0.4 0.91 9.3 0.0 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain PSII_Pbs27 PF13326.6 ORZ02876.1 - 0.11 12.8 7.0 0.054 13.8 0.7 2.7 2 0 0 2 2 2 0 Photosystem II Pbs27 DEAD PF00270.29 ORZ02877.1 - 3.1e-46 157.4 0.0 1.6e-45 155.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ02877.1 - 9.1e-23 80.7 3.1 2.4e-22 79.4 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORZ02877.1 - 2.7e-19 69.2 0.4 4.9e-19 68.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 ORZ02877.1 - 0.06 12.6 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Pox_Ag35 PF03286.14 ORZ02877.1 - 0.64 9.8 10.9 1 9.1 10.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3306 PF11748.8 ORZ02877.1 - 0.88 10.5 11.6 1.8 9.5 11.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Spore_coat_CotO PF14153.6 ORZ02877.1 - 5.3 6.9 16.4 8.4 6.3 16.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Roughex PF06020.11 ORZ02877.1 - 5.3 6.0 12.3 8 5.4 12.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein 6PF2K PF01591.18 ORZ02878.1 - 1.1e-66 224.3 0.1 1.7e-66 223.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORZ02878.1 - 3.2e-33 115.1 0.0 4.8e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SET PF00856.28 ORZ02879.1 - 0.005 17.3 0.5 0.032 14.6 0.5 2.2 1 1 0 1 1 1 1 SET domain DUF2802 PF10975.8 ORZ02879.1 - 0.42 10.8 4.4 0.82 9.8 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) SUIM_assoc PF16619.5 ORZ02879.1 - 1 9.5 10.5 2.3 8.3 9.6 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2423 PF10338.9 ORZ02880.1 - 1.1e-12 47.9 2.8 1.1e-12 47.9 2.8 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) RPN2_C PF18004.1 ORZ02880.1 - 1.1 9.2 15.8 1.3 9.0 15.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Borrelia_P83 PF05262.11 ORZ02880.1 - 2.6 6.4 16.3 2.9 6.3 16.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 ORZ02880.1 - 3.1 6.0 9.6 3.3 5.9 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORZ02880.1 - 5.1 6.8 12.0 5.3 6.8 12.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 ORZ02880.1 - 9.5 5.7 11.8 11 5.5 11.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Clathrin PF00637.20 ORZ02881.1 - 2.5e-196 643.4 44.0 6.2e-35 120.2 0.3 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 ORZ02881.1 - 3.2e-29 100.6 0.0 1.6e-28 98.4 0.0 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 ORZ02881.1 - 3.8e-28 96.4 0.9 6.8e-06 26.1 0.0 6.7 6 0 0 6 6 6 5 Clathrin propeller repeat Coatomer_WDAD PF04053.14 ORZ02881.1 - 2.2e-08 33.6 4.8 0.00028 20.1 0.1 3.8 4 0 0 4 4 4 2 Coatomer WD associated region Clathrin-link PF09268.10 ORZ02881.1 - 3.6e-08 32.6 0.1 1.2e-07 31.0 0.1 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 ORZ02881.1 - 0.00021 20.9 1.6 4.6 7.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ02881.1 - 0.0009 19.1 5.1 3.7 7.8 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ02881.1 - 0.01 15.9 3.3 27 5.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ02881.1 - 0.035 13.8 0.3 0.035 13.8 0.3 3.1 3 0 0 3 3 3 0 TPR repeat SlyX PF04102.12 ORZ02881.1 - 0.12 13.0 0.6 0.46 11.1 0.6 2.1 1 0 0 1 1 1 0 SlyX TPR_17 PF13431.6 ORZ02881.1 - 1.2 9.6 4.3 59 4.4 0.2 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ02881.1 - 4.5 7.6 7.0 40 4.5 0.1 4.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 IF4E PF01652.18 ORZ02883.1 - 9.3e-24 84.0 0.0 1.5e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RRM_1 PF00076.22 ORZ02886.1 - 1.6e-33 114.3 1.1 2.1e-18 65.9 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 ORZ02886.1 - 0.0011 18.8 0.0 1.5 8.6 0.0 2.7 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 ORZ02886.1 - 0.004 16.7 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ02886.1 - 0.01 16.0 0.1 2.2 8.4 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif CS PF04969.16 ORZ02887.1 - 1.9e-20 73.7 1.3 2.6e-20 73.2 0.4 1.7 2 0 0 2 2 2 1 CS domain Sulfatase PF00884.23 ORZ02888.1 - 1.4e-43 149.4 2.3 1.9e-43 149.0 2.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ORZ02888.1 - 0.015 14.9 1.0 0.039 13.5 0.1 1.9 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase QSregVF_b PF12843.7 ORZ02888.1 - 0.062 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor DUF229 PF02995.17 ORZ02888.1 - 0.11 11.1 0.3 0.19 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Ribosomal_60s PF00428.19 ORZ02889.1 - 6.1e-26 90.8 9.7 7.4e-26 90.6 9.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 ORZ02889.1 - 0.065 13.7 2.2 7.5 7.0 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2408 PF10303.9 ORZ02890.1 - 2.6e-44 151.1 3.2 3e-21 76.4 0.0 5.0 2 2 1 4 4 4 4 Protein of unknown function (DUF2408) APG6_N PF17675.1 ORZ02890.1 - 0.016 15.7 5.3 0.82 10.2 1.5 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region HTH_19 PF12844.7 ORZ02890.1 - 0.12 12.4 0.2 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4201 PF13870.6 ORZ02890.1 - 0.26 11.0 2.9 2 8.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 ORZ02890.1 - 0.43 10.6 10.0 0.11 12.6 0.9 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SesA PF17107.5 ORZ02890.1 - 0.43 10.8 2.9 2.5 8.3 0.1 3.3 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Snapin_Pallidin PF14712.6 ORZ02890.1 - 1.2 9.7 8.5 4.2 7.9 0.2 4.5 4 1 1 5 5 5 0 Snapin/Pallidin Metallophos PF00149.28 ORZ02891.1 - 9.2e-36 124.3 0.1 1.4e-35 123.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORZ02891.1 - 3.1e-15 56.3 0.1 5.8e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Androgen_recep PF02166.16 ORZ02891.1 - 4.4 6.0 6.5 6.2 5.5 6.5 1.1 1 0 0 1 1 1 0 Androgen receptor zf-H2C2_2 PF13465.6 ORZ02892.1 - 3.2e-10 40.0 5.5 5.1e-08 33.0 0.9 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ02892.1 - 4.4e-06 27.1 11.3 0.0016 19.1 2.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORZ02892.1 - 1.6e-05 25.1 13.0 8.3e-05 22.8 3.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORZ02892.1 - 0.00027 21.1 3.3 0.35 11.2 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORZ02892.1 - 0.00071 19.3 1.8 0.0015 18.3 1.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc-finger domain DUF2256 PF10013.9 ORZ02892.1 - 0.007 16.5 4.1 0.28 11.3 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-Di19 PF05605.12 ORZ02892.1 - 0.02 15.1 3.8 0.023 15.0 3.8 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 ORZ02892.1 - 0.042 14.2 4.1 1.7 9.0 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C5HCH PF17982.1 ORZ02892.1 - 0.12 12.6 8.6 1.1 9.4 8.5 2.0 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-C2H2_6 PF13912.6 ORZ02892.1 - 0.16 12.0 6.9 2.3 8.3 0.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 ORZ02892.1 - 0.21 12.1 5.9 0.46 11.0 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORZ02892.1 - 5.7 6.8 9.0 0.14 12.0 2.4 1.7 2 0 0 2 2 2 0 zinc-finger C2H2-type AAA PF00004.29 ORZ02893.1 - 2e-44 151.2 0.2 7.7e-44 149.3 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ02893.1 - 8.8e-11 41.4 0.1 2.5e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORZ02893.1 - 5.1e-10 39.2 0.2 4e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORZ02893.1 - 2.3e-09 37.4 0.1 6.7e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORZ02893.1 - 2.5e-08 34.5 2.6 1.4e-05 25.6 0.0 3.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 ORZ02893.1 - 1.7e-07 31.5 0.0 4.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORZ02893.1 - 3.1e-06 26.5 0.0 6.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORZ02893.1 - 8.8e-05 22.8 1.6 0.011 16.0 0.1 2.6 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 ORZ02893.1 - 0.00013 21.9 0.1 0.0094 15.9 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORZ02893.1 - 0.00015 22.3 0.0 0.0019 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORZ02893.1 - 0.00022 21.0 0.0 0.00059 19.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 ORZ02893.1 - 0.00043 20.6 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORZ02893.1 - 0.00044 20.3 0.1 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORZ02893.1 - 0.0015 18.4 0.1 0.0062 16.5 0.0 2.1 3 0 0 3 3 1 1 NTPase AAA_30 PF13604.6 ORZ02893.1 - 0.0019 17.9 0.2 0.0049 16.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORZ02893.1 - 0.0021 17.6 0.1 0.02 14.4 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 ORZ02893.1 - 0.0036 17.7 0.0 0.0074 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 ORZ02893.1 - 0.0037 17.0 0.2 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 ORZ02893.1 - 0.0054 16.9 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 ORZ02893.1 - 0.0077 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 ORZ02893.1 - 0.0083 15.6 0.0 0.65 9.4 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 ORZ02893.1 - 0.0088 16.0 0.2 0.065 13.2 0.0 2.3 1 1 1 2 2 2 1 NACHT domain TIP49 PF06068.13 ORZ02893.1 - 0.0091 15.2 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 ORZ02893.1 - 0.017 14.7 1.7 0.046 13.3 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_3 PF07726.11 ORZ02893.1 - 0.019 14.8 0.1 0.088 12.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORZ02893.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORZ02893.1 - 0.028 14.2 0.1 0.095 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 ORZ02893.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_19 PF13245.6 ORZ02893.1 - 0.04 14.3 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORZ02893.1 - 0.042 13.6 0.5 1.4 8.6 0.0 3.1 4 1 0 4 4 4 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 ORZ02893.1 - 0.078 11.8 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase ATPase PF06745.13 ORZ02893.1 - 0.081 12.3 0.0 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 ORZ02893.1 - 0.096 12.6 1.2 0.9 9.4 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 ORZ02893.1 - 0.096 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CAP59_mtransfer PF11735.8 ORZ02893.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 ABC_tran PF00005.27 ORZ02893.1 - 0.12 12.9 0.0 0.41 11.2 0.0 2.1 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 ORZ02893.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 ORZ02893.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ppx-GppA PF02541.16 ORZ02894.1 - 1.5e-47 162.4 0.0 3.6e-46 157.9 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family zf-MYND PF01753.18 ORZ02895.1 - 7.9e-08 32.3 16.6 1.9e-07 31.0 16.6 1.7 1 0 0 1 1 1 1 MYND finger SNAP PF14938.6 ORZ02897.1 - 2.6e-97 325.7 19.7 2.9e-97 325.5 19.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 ORZ02897.1 - 7.4e-08 32.6 14.5 1.1e-05 25.6 3.0 4.3 1 1 4 5 5 5 2 Tetratricopeptide repeat NSF PF02071.20 ORZ02897.1 - 3.7e-05 23.7 15.4 0.17 12.7 0.1 6.9 5 3 1 7 7 7 1 Aromatic-di-Alanine (AdAR) repeat TPR_2 PF07719.17 ORZ02897.1 - 5.7e-05 22.9 28.3 0.84 9.9 0.2 7.9 5 2 3 8 8 8 3 Tetratricopeptide repeat HHH_8 PF14716.6 ORZ02897.1 - 0.00014 22.1 6.0 0.18 12.2 0.2 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix domain TPR_6 PF13174.6 ORZ02897.1 - 0.00091 19.7 15.4 11 6.9 0.0 6.9 5 2 3 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ02897.1 - 0.0011 18.9 15.2 6.8 7.0 1.7 6.2 3 2 1 4 4 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.8 ORZ02897.1 - 0.0051 16.4 2.3 0.049 13.2 1.8 2.2 1 1 0 1 1 1 1 Foie gras liver health family 1 TPR_1 PF00515.28 ORZ02897.1 - 0.016 15.0 22.1 2.3 8.2 0.1 6.9 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ02897.1 - 0.033 14.4 12.6 3.9 7.9 0.1 5.8 6 1 0 6 6 5 0 Tetratricopeptide repeat Lyase_8_N PF08124.11 ORZ02897.1 - 0.084 11.8 1.0 0.17 10.8 0.5 1.7 1 1 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain TPR_11 PF13414.6 ORZ02897.1 - 0.39 10.4 15.9 5.3 6.8 0.0 5.9 5 1 3 8 8 8 0 TPR repeat MIT PF04212.18 ORZ02897.1 - 0.88 9.7 25.7 2.4 8.3 3.1 5.7 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 ORZ02897.1 - 7.3 6.6 12.1 7.9 6.5 0.2 4.6 3 1 1 5 5 5 0 Tetratricopeptide repeat AIG1 PF04548.16 ORZ02899.1 - 3.5e-20 72.2 0.0 5.5e-20 71.6 0.0 1.4 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 ORZ02899.1 - 6e-12 45.7 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORZ02899.1 - 4.4e-07 30.1 0.1 0.0012 18.9 0.0 2.4 1 1 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORZ02899.1 - 4.5e-06 26.7 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase GBP PF02263.19 ORZ02899.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.27 ORZ02899.1 - 0.0086 16.6 0.0 0.012 16.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORZ02899.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 ORZ02899.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 ORZ02899.1 - 0.22 11.8 0.8 3.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Na_sulph_symp PF00939.19 ORZ02900.1 - 3.9e-29 102.0 31.4 5.4e-29 101.6 31.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 ORZ02900.1 - 4e-25 89.6 14.1 1.3e-11 45.1 0.2 3.1 1 1 2 3 3 3 3 SPX domain CitMHS PF03600.16 ORZ02900.1 - 1.4e-24 86.8 52.1 3.5e-21 75.7 30.7 2.2 1 1 1 2 2 2 2 Citrate transporter COG5 PF10392.9 ORZ02900.1 - 0.055 13.7 0.4 0.12 12.6 0.4 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 P21-Arc PF04062.14 ORZ02901.1 - 1.5e-80 269.3 0.1 1.7e-80 269.1 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUSP PF06337.12 ORZ02902.1 - 0.00016 22.2 0.0 0.00094 19.8 0.0 2.1 2 0 0 2 2 2 1 DUSP domain HNH PF01844.23 ORZ02902.1 - 0.0022 18.1 0.4 0.007 16.5 0.3 2.0 2 1 0 2 2 2 1 HNH endonuclease C1_1 PF00130.22 ORZ02902.1 - 0.035 14.0 3.3 0.082 12.8 1.0 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-UBP PF02148.19 ORZ02902.1 - 0.043 14.1 4.1 0.34 11.3 4.1 2.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-FLZ PF04570.14 ORZ02902.1 - 0.75 9.3 5.4 1.4 8.5 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Ephrin_rec_like PF07699.13 ORZ02902.1 - 0.84 9.4 3.9 3.1 7.6 3.9 1.9 1 1 0 1 1 1 0 Putative ephrin-receptor like DnaJ PF00226.31 ORZ02903.1 - 4.3e-21 74.8 0.7 1.8e-20 72.8 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 ORZ02903.1 - 6.7e-21 74.6 0.0 1.9e-20 73.1 0.0 1.6 1 1 0 1 1 1 1 Sec63 Brl domain TssO PF17561.2 ORZ02903.1 - 0.2 11.7 0.3 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Type VI secretion system, TssO Ribosomal_L19 PF01245.20 ORZ02905.1 - 2.3e-20 72.6 0.1 3.5e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 DUF3104 PF11302.8 ORZ02905.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Memo PF01875.17 ORZ02906.1 - 1.4e-81 273.6 0.0 1.6e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein GFRP PF06399.13 ORZ02906.1 - 0.032 14.1 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) RrnaAD PF00398.20 ORZ02908.1 - 3e-67 226.5 0.0 4e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ORZ02908.1 - 1.3e-06 29.0 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ02908.1 - 0.00026 21.5 0.0 0.00058 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORZ02908.1 - 0.00064 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 ORZ02908.1 - 0.0019 18.9 0.0 0.0054 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORZ02908.1 - 0.009 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 ORZ02908.1 - 0.0091 15.6 0.2 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ORZ02908.1 - 0.0095 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 ORZ02908.1 - 0.015 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cons_hypoth95 PF03602.15 ORZ02908.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 ORZ02908.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 ORZ02908.1 - 0.033 13.8 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ORZ02908.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4744 PF15918.5 ORZ02908.1 - 0.11 13.3 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) TrbE PF11100.8 ORZ02910.1 - 0.32 11.3 3.5 18 5.6 0.0 3.2 3 0 0 3 3 3 0 Conjugal transfer protein TrbE NTP_transferase PF00483.23 ORZ02911.1 - 3.1e-52 177.6 0.0 4.2e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORZ02911.1 - 1.9e-12 46.4 9.7 9.6e-10 37.8 4.8 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORZ02911.1 - 4.7e-09 36.8 0.0 7.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORZ02911.1 - 0.0008 19.1 3.0 0.0008 19.1 3.0 3.3 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORZ02911.1 - 0.012 13.8 0.1 0.017 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 ORZ02911.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase AAA PF00004.29 ORZ02914.1 - 1.6e-40 138.6 0.3 1.6e-39 135.3 0.0 2.7 3 1 1 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ02914.1 - 5.9e-11 42.0 0.6 1.8e-10 40.4 0.3 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 ORZ02914.1 - 2.6e-05 24.5 1.2 0.008 16.5 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 ORZ02914.1 - 3.5e-05 24.0 0.1 0.00018 21.7 0.0 2.3 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORZ02914.1 - 7.6e-05 22.5 0.0 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORZ02914.1 - 0.00017 22.0 0.1 0.036 14.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 ORZ02914.1 - 0.0002 21.9 0.0 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORZ02914.1 - 0.00029 20.9 0.0 0.01 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORZ02914.1 - 0.00031 20.8 0.1 0.0018 18.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORZ02914.1 - 0.00048 19.4 0.8 0.0016 17.8 0.1 2.1 2 1 1 3 3 3 1 TIP49 P-loop domain IstB_IS21 PF01695.17 ORZ02914.1 - 0.00099 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORZ02914.1 - 0.0014 18.1 0.0 0.0032 16.9 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORZ02914.1 - 0.0022 18.2 0.0 0.0065 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORZ02914.1 - 0.0023 18.3 0.0 0.0095 16.3 0.0 2.2 1 1 0 1 1 1 1 RNA helicase DUF815 PF05673.13 ORZ02914.1 - 0.0038 16.4 0.1 0.2 10.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NCD2 PF04905.13 ORZ02914.1 - 0.0083 16.1 0.1 0.051 13.5 0.0 2.4 2 0 0 2 2 2 1 NAB conserved region 2 (NCD2) AAA_28 PF13521.6 ORZ02914.1 - 0.011 16.0 0.1 0.082 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORZ02914.1 - 0.022 14.3 0.6 0.27 10.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain PELOTA_1 PF15608.6 ORZ02914.1 - 0.024 14.5 0.4 0.066 13.1 0.4 1.7 1 0 0 1 1 1 0 PELOTA RNA binding domain TniB PF05621.11 ORZ02914.1 - 0.025 14.0 0.1 2.1 7.7 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein AAA_24 PF13479.6 ORZ02914.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORZ02914.1 - 0.033 13.7 0.1 0.11 12.0 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ORZ02914.1 - 0.038 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 ORZ02914.1 - 0.049 13.0 0.3 0.28 10.5 0.1 2.3 1 1 0 2 2 2 0 KaiC DEAD PF00270.29 ORZ02914.1 - 0.063 13.0 0.2 0.32 10.7 0.2 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.17 ORZ02914.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 ORZ02914.1 - 0.083 13.4 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 ORZ02914.1 - 0.086 12.3 0.1 0.24 10.8 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 ORZ02914.1 - 0.088 12.5 0.0 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Glyco_hydro_70 PF02324.16 ORZ02914.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 TsaE PF02367.17 ORZ02914.1 - 0.14 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dTDP_sugar_isom PF00908.17 ORZ02914.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Pkinase PF00069.25 ORZ02917.1 - 1.2e-78 264.1 0.0 1.9e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02917.1 - 5.8e-43 147.0 0.0 9.2e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ02917.1 - 9.8e-10 38.2 0.0 1.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORZ02917.1 - 0.00046 19.6 0.6 0.0013 18.2 0.4 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORZ02917.1 - 0.00064 18.8 0.1 0.0016 17.5 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORZ02917.1 - 0.0093 15.9 0.0 0.03 14.2 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORZ02917.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 UQ_con PF00179.26 ORZ02918.1 - 4.7e-49 165.7 0.0 5.2e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORZ02918.1 - 0.0011 18.6 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORZ02918.1 - 0.14 12.4 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain DNA_primase_lrg PF04104.14 ORZ02919.1 - 6.8e-90 301.1 0.2 1e-89 300.5 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Abhydrolase_3 PF07859.13 ORZ02920.1 - 1.8e-38 132.5 0.0 2.4e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORZ02920.1 - 1.6e-20 73.4 0.0 2.1e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORZ02920.1 - 0.00074 19.1 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 ORZ02920.1 - 0.0034 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) COesterase PF00135.28 ORZ02920.1 - 0.084 11.7 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family ZapB PF06005.12 ORZ02921.1 - 0.11 13.0 3.9 9.9 6.7 1.0 2.6 2 0 0 2 2 2 0 Cell division protein ZapB PepSY_TM_like_2 PF16357.5 ORZ02921.1 - 0.13 12.3 0.1 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative PepSY_TM-like Ribonuc_L-PSP PF01042.21 ORZ02922.1 - 3e-43 146.7 0.3 3.6e-43 146.4 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4530 PF15039.6 ORZ02922.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) GPI-anchored PF10342.9 ORZ02923.1 - 3.9e-08 33.9 1.3 5.7e-08 33.4 0.3 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PapD_C PF02753.17 ORZ02923.1 - 0.015 15.6 0.2 0.041 14.2 0.2 1.7 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain RabGAP-TBC PF00566.18 ORZ02924.1 - 3.9e-48 163.9 0.4 8.3e-48 162.9 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain UQ_con PF00179.26 ORZ02926.1 - 2.8e-47 159.9 0.0 3.6e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORZ02926.1 - 0.00056 19.6 0.0 0.00085 19.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORZ02926.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 ORZ02926.1 - 0.072 13.4 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 RWD domain Apt1 PF10351.9 ORZ02926.1 - 0.38 9.6 2.4 0.45 9.3 2.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPR_1 PF00515.28 ORZ02927.1 - 5.3e-38 127.3 40.6 0.00012 21.8 0.9 16.2 17 0 0 17 17 17 8 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ02927.1 - 1.1e-35 121.9 35.4 6.8e-11 42.5 0.2 11.2 8 3 2 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ02927.1 - 4.2e-34 113.9 47.5 0.00025 20.9 0.5 16.1 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ02927.1 - 1.9e-30 102.5 32.0 0.01 16.0 0.5 15.3 16 0 0 16 16 16 8 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ02927.1 - 3.8e-29 101.1 18.8 7.4e-07 29.7 0.1 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ02927.1 - 1.1e-28 99.4 47.2 1.7e-05 25.0 1.2 12.9 7 4 6 14 14 14 9 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ02927.1 - 1.1e-24 84.9 24.9 0.00024 21.7 0.2 14.4 6 5 9 15 15 15 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ02927.1 - 3.1e-24 83.2 30.7 0.00019 21.2 0.3 14.7 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ02927.1 - 2.1e-20 72.0 37.0 0.0019 18.7 0.0 13.3 15 0 0 15 15 12 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ02927.1 - 1.9e-17 62.3 22.0 0.07 13.5 0.1 13.8 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORZ02927.1 - 8.7e-14 50.9 39.4 0.037 13.9 0.9 13.8 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ02927.1 - 1.3e-12 47.2 35.6 5e-05 22.9 0.8 12.4 12 2 3 15 15 15 4 TPR repeat ANAPC3 PF12895.7 ORZ02927.1 - 1.3e-12 47.7 38.3 0.0016 18.6 1.2 8.8 6 3 2 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORZ02927.1 - 1.2e-09 37.8 24.6 5.9e-06 25.7 0.7 7.2 5 2 2 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ02927.1 - 1.6e-07 31.4 20.1 0.45 10.7 0.3 9.4 9 1 2 11 11 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORZ02927.1 - 2.3e-07 30.8 0.1 6.6 7.7 0.0 6.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORZ02927.1 - 6.6e-07 29.6 15.3 0.00051 20.3 0.5 7.9 6 1 2 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.10 ORZ02927.1 - 6.3e-06 25.4 2.4 0.066 12.2 0.0 3.5 3 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) PknG_TPR PF16918.5 ORZ02927.1 - 7.6e-06 24.9 0.9 0.072 11.8 0.0 3.0 2 1 1 3 3 3 2 Protein kinase G tetratricopeptide repeat NARP1 PF12569.8 ORZ02927.1 - 3.7e-05 22.8 18.0 0.0046 15.9 4.7 5.0 3 2 1 4 4 4 2 NMDA receptor-regulated protein 1 TPPII_N PF12583.8 ORZ02927.1 - 0.00027 21.5 0.5 0.91 10.1 0.0 3.4 2 2 2 4 4 4 1 Tripeptidyl peptidase II N terminal HrpB1_HrpK PF09613.10 ORZ02927.1 - 0.0004 20.0 8.3 1 9.0 0.0 5.3 5 1 1 6 6 6 2 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 ORZ02927.1 - 0.0022 17.5 7.6 0.29 10.5 0.2 3.9 4 0 0 4 4 4 2 Coatomer epsilon subunit SHNi-TPR PF10516.9 ORZ02927.1 - 0.0026 17.2 1.7 3.8 7.0 0.0 4.5 5 0 0 5 5 5 1 SHNi-TPR SNAP PF14938.6 ORZ02927.1 - 0.0039 16.7 15.4 1.3 8.4 0.3 5.8 4 1 2 6 6 6 2 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 ORZ02927.1 - 0.011 15.8 1.7 0.011 15.8 1.7 7.7 8 1 1 9 9 8 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 ORZ02927.1 - 0.011 15.4 23.9 0.14 11.8 0.5 6.4 3 3 2 5 5 5 0 Tetratricopeptide repeat-like domain Type_III_YscG PF09477.10 ORZ02927.1 - 0.032 14.3 0.9 0.24 11.4 0.0 3.0 3 0 0 3 3 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TetR_C_25 PF17933.1 ORZ02927.1 - 0.053 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TPR_5 PF12688.7 ORZ02927.1 - 0.087 13.1 11.7 12 6.2 0.1 5.7 6 1 1 7 7 5 0 Tetratrico peptide repeat DUF4598 PF15370.6 ORZ02927.1 - 0.12 12.9 0.5 1.7 9.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) PPR PF01535.20 ORZ02927.1 - 0.18 12.2 9.7 18 5.9 0.0 7.1 8 0 0 8 8 6 0 PPR repeat Rapsyn_N PF10579.9 ORZ02927.1 - 0.24 11.5 7.3 8.3 6.6 0.0 5.5 7 1 1 8 8 6 0 Rapsyn N-terminal myristoylation and linker region PPR_2 PF13041.6 ORZ02927.1 - 0.79 10.0 6.6 7.6 6.8 0.0 5.5 6 0 0 6 6 5 0 PPR repeat family Alkyl_sulf_dimr PF14863.6 ORZ02927.1 - 1 9.8 6.2 1.5 9.3 0.2 3.8 4 0 0 4 4 2 0 Alkyl sulfatase dimerisation DUF202 PF02656.15 ORZ02929.1 - 0.00022 21.6 4.4 0.00022 21.6 4.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2721 PF11026.8 ORZ02929.1 - 0.0025 17.7 0.3 0.0025 17.7 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) Big_3_4 PF13754.6 ORZ02929.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function VPDSG-CTERM PF18205.1 ORZ02929.1 - 0.02 14.7 1.7 0.02 14.7 1.7 2.5 3 0 0 3 3 3 0 VPDSG-CTERM motif PEP-CTERM PF07589.11 ORZ02929.1 - 3.5 7.8 5.9 0.95 9.6 1.5 2.2 2 0 0 2 2 2 0 PEP-CTERM motif UPF0183 PF03676.14 ORZ02930.1 - 1.1e-97 327.8 0.0 1.3e-59 202.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) Nop53 PF07767.11 ORZ02931.1 - 2.8e-86 290.4 40.5 2.8e-86 290.4 40.5 2.0 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) DSS1_SEM1 PF05160.13 ORZ02932.1 - 8.6e-22 77.0 22.5 8.6e-22 77.0 22.5 1.3 1 1 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 ORZ02932.1 - 0.031 14.1 6.0 0.034 14.0 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Cwf_Cwc_15 PF04889.12 ORZ02932.1 - 0.1 12.3 10.6 0.12 12.1 10.6 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SUR7 PF06687.12 ORZ02933.1 - 1.6e-23 83.4 9.7 2.2e-23 83.0 9.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3611 PF12263.8 ORZ02933.1 - 0.0049 16.8 2.3 0.0049 16.8 2.3 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3611) DUF4293 PF14126.6 ORZ02933.1 - 0.014 15.6 0.6 0.014 15.6 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2207 PF09972.9 ORZ02933.1 - 0.22 10.3 1.8 0.26 10.0 1.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ODV-E18 PF10717.9 ORZ02933.1 - 0.53 10.2 4.7 1.9 8.4 2.4 2.2 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 SdpI PF13630.6 ORZ02933.1 - 8.6 6.6 8.8 2.9 8.1 2.8 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family CoA_transf_3 PF02515.17 ORZ02934.1 - 4.1e-124 414.4 0.0 4.6e-124 414.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SRP19 PF01922.17 ORZ02935.1 - 3.6e-30 104.8 0.1 7.6e-30 103.7 0.1 1.6 1 0 0 1 1 1 1 SRP19 protein GET2 PF08690.10 ORZ02935.1 - 2.6 7.6 4.9 0.32 10.6 0.8 1.5 2 0 0 2 2 2 0 GET complex subunit GET2 Tfb2 PF03849.14 ORZ02936.1 - 1.4e-145 484.8 0.2 1.7e-145 484.5 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 ORZ02936.1 - 1.3e-28 99.2 0.0 2.9e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 ORZ02936.1 - 0.00026 21.2 0.0 0.00052 20.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSBP1 PF06825.12 ORZ02936.1 - 0.05 13.5 0.1 0.05 13.5 0.1 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DEAD PF00270.29 ORZ02937.1 - 3.8e-25 88.7 0.1 2e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ORZ02937.1 - 1.7e-13 50.9 0.0 3.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORZ02937.1 - 6.1e-11 42.6 0.1 2e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sec63 PF02889.16 ORZ02937.1 - 1.4e-09 37.5 0.1 2.8e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Sec63 Brl domain AAA_19 PF13245.6 ORZ02937.1 - 3.6e-05 24.1 0.2 0.00076 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORZ02937.1 - 0.00017 21.9 0.0 0.00044 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 ORZ02937.1 - 0.0012 19.4 0.0 0.0034 18.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_30 PF13604.6 ORZ02937.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol_lambd_f PF10391.9 ORZ02937.1 - 0.01 15.6 0.2 0.089 12.6 0.0 2.6 4 0 0 4 4 4 0 Fingers domain of DNA polymerase lambda PhoH PF02562.16 ORZ02937.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 ORZ02937.1 - 0.037 14.4 0.4 0.49 10.8 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORZ02937.1 - 0.12 12.4 0.0 1.3 9.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain STAR_dimer PF16544.5 ORZ02937.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein ATPase PF06745.13 ORZ02937.1 - 0.14 11.4 0.0 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 KaiC Ribosomal_L33 PF00471.20 ORZ02939.1 - 5.4e-10 39.6 0.0 6.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 zinc_ribbon_6 PF14599.6 ORZ02941.1 - 3.7e-24 84.5 5.2 3.7e-24 84.5 5.2 4.6 4 3 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 ORZ02941.1 - 7.3e-20 71.2 20.4 7.3e-20 71.2 20.4 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 ORZ02941.1 - 8.7e-07 29.2 6.2 8.7e-07 29.2 6.2 6.1 3 2 3 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 ORZ02941.1 - 0.00018 21.4 8.3 0.00018 21.4 8.3 7.1 4 3 2 6 6 6 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORZ02941.1 - 0.00095 19.0 8.2 0.00095 19.0 8.2 6.5 3 3 5 8 8 8 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORZ02941.1 - 0.0032 17.4 6.3 0.0032 17.4 6.3 4.5 5 1 0 5 5 5 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORZ02941.1 - 0.012 15.3 1.7 0.012 15.3 1.7 5.2 6 0 0 6 6 6 0 RING-like zinc finger Aminotran_1_2 PF00155.21 ORZ02942.1 - 4.4e-62 210.3 0.0 5.7e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORZ02942.1 - 2.3e-07 30.4 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORZ02942.1 - 0.0038 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORZ02942.1 - 0.022 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORZ02942.1 - 0.09 11.3 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TFIIA PF03153.13 ORZ02942.1 - 4 7.3 8.4 5.7 6.8 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NST1 PF13945.6 ORZ02944.1 - 4.2e-45 154.2 22.9 4.2e-45 154.2 22.9 4.2 3 2 1 4 4 4 1 Salt tolerance down-regulator CUE PF02845.16 ORZ02945.1 - 1.6e-07 30.9 0.0 3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain COPIIcoated_ERV PF07970.12 ORZ02946.1 - 6.5e-75 251.8 0.3 9.9e-75 251.2 0.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORZ02946.1 - 1e-26 93.1 0.0 2.6e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IMD PF08397.11 ORZ02947.1 - 1.4e-08 34.4 4.5 2e-08 33.9 4.5 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain Filament PF00038.21 ORZ02947.1 - 0.00025 20.7 8.3 0.0019 17.9 5.7 2.1 2 0 0 2 2 2 1 Intermediate filament protein PI3K_P85_iSH2 PF16454.5 ORZ02947.1 - 0.0078 15.8 0.5 0.0078 15.8 0.5 2.7 2 1 1 3 3 3 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MIP-T3_C PF17749.1 ORZ02947.1 - 0.017 15.1 2.0 0.041 13.9 1.6 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Arfaptin PF06456.13 ORZ02947.1 - 0.018 14.6 4.2 0.062 12.9 4.2 1.8 1 1 0 1 1 1 0 Arfaptin-like domain ALIX_LYPXL_bnd PF13949.6 ORZ02947.1 - 0.13 11.6 7.5 0.088 12.1 4.7 1.9 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV HAUS6_N PF14661.6 ORZ02947.1 - 0.53 9.8 7.2 0.26 10.9 4.8 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 ORZ02947.1 - 0.88 10.1 7.9 0.33 11.5 4.5 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 ORZ02947.1 - 0.88 10.1 6.4 0.84 10.1 0.5 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.14 ORZ02947.1 - 0.98 9.8 9.1 1.7 9.0 9.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Rep_fac-A_C PF08646.10 ORZ02948.1 - 7.3e-49 165.3 5.1 3.4e-47 159.9 1.1 3.0 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 ORZ02948.1 - 3.8e-33 113.3 1.0 1.2e-32 111.7 0.1 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 ORZ02948.1 - 1.5e-17 63.5 0.2 4e-17 62.1 0.2 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 ORZ02948.1 - 3.7e-11 42.8 3.2 3.4e-09 36.5 0.0 4.2 4 1 1 5 5 5 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 ORZ02948.1 - 4e-06 26.7 1.0 9.4e-05 22.2 0.1 2.8 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 zinc-ribbons_6 PF07191.12 ORZ02948.1 - 0.092 12.7 1.7 0.2 11.6 1.7 1.5 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 ORZ02948.1 - 0.45 10.1 3.8 13 5.5 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Herpes_capsid PF06112.11 ORZ02948.1 - 0.6 10.2 6.7 1.3 9.1 6.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AIRC PF00731.20 ORZ02949.1 - 1.8e-63 212.5 1.3 4.7e-63 211.2 1.3 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 ORZ02949.1 - 1e-61 207.5 0.0 1.9e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 ORZ02949.1 - 6e-19 67.5 0.1 1.5e-18 66.2 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain AlaDh_PNT_C PF01262.21 ORZ02949.1 - 0.00039 19.8 0.1 0.0011 18.3 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 ORZ02949.1 - 0.00042 19.9 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 ORZ02949.1 - 0.00092 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 3HCDH_N PF02737.18 ORZ02949.1 - 0.018 14.9 0.1 0.047 13.6 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.14 ORZ02949.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Beach PF02138.18 ORZ02950.1 - 7.8e-42 143.5 0.0 1.5e-41 142.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Pkinase PF00069.25 ORZ02950.1 - 3.9e-08 33.0 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02950.1 - 0.00025 20.4 0.0 0.00067 19.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ02950.1 - 0.0065 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORZ02950.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC4_WD40 PF12894.7 ORZ02951.1 - 2.4e-13 50.2 0.0 0.00047 20.4 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORZ02951.1 - 3e-12 46.8 7.1 9.2e-05 23.1 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.6 ORZ02951.1 - 0.0013 18.3 0.1 0.014 15.0 0.1 2.2 1 1 1 2 2 2 1 PQQ-like domain NUP214 PF16755.5 ORZ02951.1 - 0.0035 16.6 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40_like PF17005.5 ORZ02951.1 - 0.06 12.7 0.0 0.93 8.8 0.0 2.5 3 1 1 4 4 4 0 WD40-like domain Frtz PF11768.8 ORZ02951.1 - 0.12 10.7 0.0 2.6 6.3 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Fumble PF03630.14 ORZ02952.1 - 1.7e-138 461.3 0.9 2.5e-138 460.8 0.9 1.2 1 0 0 1 1 1 1 Fumble CopB PF05275.11 ORZ02952.1 - 0.025 14.1 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Copper resistance protein B precursor (CopB) Glyco_hydro_3_C PF01915.22 ORZ02953.1 - 4.4e-59 199.9 0.0 7.1e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORZ02953.1 - 2.7e-44 151.8 0.0 4.6e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORZ02953.1 - 7.6e-23 80.4 0.0 1.5e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cyclin PF08613.11 ORZ02954.1 - 1.1e-07 32.4 0.0 1.6e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORZ02954.1 - 8e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Lon_C PF05362.13 ORZ02956.1 - 1.4e-68 230.5 0.2 2e-68 230.0 0.2 1.2 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ORZ02956.1 - 1.2e-22 80.8 0.0 2.1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORZ02956.1 - 2.3e-11 43.9 0.0 5.5e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORZ02956.1 - 3.2e-10 39.9 0.0 6.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.11 ORZ02956.1 - 4.3e-07 29.8 0.0 8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORZ02956.1 - 1.9e-06 27.7 0.0 4.5e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORZ02956.1 - 2.8e-06 27.7 0.1 0.00011 22.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ02956.1 - 5.8e-06 26.8 0.8 2e-05 25.0 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_PrkA PF08298.11 ORZ02956.1 - 2.1e-05 23.6 0.0 3.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.6 ORZ02956.1 - 2.5e-05 24.3 0.0 5.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORZ02956.1 - 4.4e-05 23.7 0.0 0.00013 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 ORZ02956.1 - 0.0003 20.7 0.1 0.002 18.1 0.0 2.3 3 0 0 3 3 2 1 NACHT domain RsgA_GTPase PF03193.16 ORZ02956.1 - 0.00037 20.4 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 ORZ02956.1 - 0.00037 20.8 0.0 0.0022 18.4 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 ORZ02956.1 - 0.00055 20.5 0.0 0.0011 19.5 0.0 1.5 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ORZ02956.1 - 0.00064 19.5 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 ORZ02956.1 - 0.00077 19.6 0.0 0.0024 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORZ02956.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 ORZ02956.1 - 0.0022 18.5 0.0 0.0046 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORZ02956.1 - 0.0045 16.9 0.0 0.011 15.7 0.1 1.7 1 1 0 1 1 1 1 NTPase AAA_17 PF13207.6 ORZ02956.1 - 0.0091 16.4 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORZ02956.1 - 0.011 15.2 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORZ02956.1 - 0.012 15.6 0.0 0.042 13.8 0.0 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ORZ02956.1 - 0.018 15.6 0.1 0.068 13.7 0.0 2.1 2 1 0 2 2 1 0 ABC transporter AAA_28 PF13521.6 ORZ02956.1 - 0.023 14.9 0.1 0.2 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORZ02956.1 - 0.03 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORZ02956.1 - 0.036 13.4 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 ORZ02956.1 - 0.037 13.9 0.0 1 9.2 0.0 2.2 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea SR-25 PF10500.9 ORZ02956.1 - 0.038 13.6 8.9 0.066 12.8 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_30 PF13604.6 ORZ02956.1 - 0.041 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORZ02956.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 ORZ02956.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 ORZ02956.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 ORZ02956.1 - 0.13 11.6 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 ORZ02956.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ORZ02956.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RA PF00788.23 ORZ02957.1 - 3e-07 31.0 0.0 0.0029 18.2 0.0 2.9 2 1 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 ORZ02957.1 - 8.3e-06 25.3 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORZ02957.1 - 0.0033 17.2 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ufm1 PF03671.14 ORZ02957.1 - 0.055 13.6 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein SH3_2 PF07653.17 ORZ02957.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain BSP_II PF05432.11 ORZ02957.1 - 1.5 8.4 23.4 0.11 12.1 8.8 2.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RSN1_7TM PF02714.15 ORZ02958.1 - 2.4e-81 273.1 32.9 2.4e-81 273.1 32.9 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORZ02958.1 - 9.2e-35 119.7 2.5 9.2e-35 119.7 2.5 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORZ02958.1 - 7.1e-31 107.8 0.0 1.7e-30 106.6 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter ATG16 PF08614.11 ORZ02960.1 - 0.0062 16.8 13.4 0.0062 16.8 13.4 2.1 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) SprA-related PF12118.8 ORZ02960.1 - 0.031 13.4 13.6 0.062 12.4 13.6 1.5 1 0 0 1 1 1 0 SprA-related family DUF1664 PF07889.12 ORZ02960.1 - 0.066 13.3 4.3 0.3 11.1 4.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) COG5 PF10392.9 ORZ02960.1 - 0.16 12.2 9.3 0.6 10.3 9.3 2.0 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Fanconi_A_N PF15865.5 ORZ02960.1 - 0.23 10.8 7.6 0.36 10.2 7.6 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Cep57_CLD_2 PF14197.6 ORZ02960.1 - 0.26 11.4 10.5 0.34 11.0 1.7 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Ndc1_Nup PF09531.10 ORZ02960.1 - 1.1 7.9 16.4 0.041 12.6 8.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TMPIT PF07851.13 ORZ02960.1 - 1.2 8.4 7.0 1.9 7.6 7.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF3347 PF11827.8 ORZ02960.1 - 1.7 8.8 21.1 0.17 12.0 16.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) SPX PF03105.19 ORZ02960.1 - 1.8 8.4 22.8 0.59 10.0 19.9 1.7 2 0 0 2 2 2 0 SPX domain Exonuc_VII_L PF02601.15 ORZ02960.1 - 5.6 6.5 16.7 0.51 9.8 11.9 1.7 3 0 0 3 3 3 0 Exonuclease VII, large subunit MCU PF04678.13 ORZ02960.1 - 8.2 6.5 9.0 2.7 8.1 5.7 1.9 2 0 0 2 2 2 0 Mitochondrial calcium uniporter MFS_1 PF07690.16 ORZ02961.1 - 8.2e-36 123.6 27.3 2.2e-35 122.2 23.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_M50B PF13398.6 ORZ02962.1 - 1.1e-51 175.3 18.7 1.4e-51 175.0 18.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like UBA PF00627.31 ORZ02963.1 - 4.7e-09 36.0 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain C2 PF00168.30 ORZ02963.1 - 0.00047 20.4 0.0 0.00097 19.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 ORZ02963.1 - 0.0087 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 TPR_8 PF13181.6 ORZ02963.1 - 0.12 12.7 1.7 0.48 10.8 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3173 PF11372.8 ORZ02963.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) DUF1771 PF08590.10 ORZ02963.1 - 5.2 7.5 9.6 3.8 8.0 4.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) TPR_2 PF07719.17 ORZ02963.1 - 6 7.2 6.8 3 8.2 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PH PF00169.29 ORZ02964.1 - 1.4e-08 35.2 0.0 1.5e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 ORZ02964.1 - 8e-05 23.0 0.2 0.0009 19.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain DAD PF02109.16 ORZ02965.1 - 1.3e-42 144.5 3.7 1.8e-42 144.0 3.7 1.2 1 0 0 1 1 1 1 DAD family GNVR PF13807.6 ORZ02965.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase TFIIF_beta PF02270.15 ORZ02966.1 - 3.6e-26 91.1 0.0 5.5e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 ORZ02966.1 - 5.7e-23 82.1 0.7 3.6e-22 79.5 0.7 2.3 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 ORZ02966.1 - 0.0092 16.8 0.0 0.016 16.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Sigma54_activ_2 PF14532.6 ORZ02966.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Acyltransferase PF01553.21 ORZ02967.1 - 2.4e-14 53.1 0.0 4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Romo1 PF10247.9 ORZ02968.1 - 9.3e-05 22.7 1.3 0.00014 22.1 1.3 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF5541 PF17695.1 ORZ02968.1 - 0.0014 19.0 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5541) HTH_13 PF11972.8 ORZ02968.1 - 0.092 12.8 0.3 0.25 11.4 0.3 1.7 1 1 0 1 1 1 0 HTH DNA binding domain WD40_4 PF16300.5 ORZ02969.1 - 1.9e-33 114.1 0.2 5.8e-19 67.7 0.0 2.6 2 0 0 2 2 2 2 Type of WD40 repeat ANAPC4_WD40 PF12894.7 ORZ02969.1 - 1.5e-13 50.8 0.0 0.0012 19.1 0.0 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORZ02969.1 - 6.8e-11 42.5 13.6 0.00085 20.1 0.1 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF1899 PF08953.11 ORZ02969.1 - 1.9e-10 40.4 0.0 7.2e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) Ge1_WD40 PF16529.5 ORZ02969.1 - 2e-06 27.0 0.1 0.0046 16.0 0.1 3.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 ORZ02969.1 - 0.0078 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 PQQ enzyme repeat Stathmin PF00836.19 ORZ02969.1 - 4.8 7.1 10.8 0.48 10.4 6.2 1.6 2 0 0 2 2 2 0 Stathmin family DNA_pol3_delta2 PF13177.6 ORZ02970.1 - 1.1e-12 48.0 0.0 2.2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ORZ02970.1 - 1.9e-07 31.6 0.0 3.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORZ02970.1 - 4.2e-07 30.1 0.1 6.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 ORZ02970.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORZ02970.1 - 0.0016 18.6 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORZ02970.1 - 0.0054 17.0 0.1 0.014 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ02970.1 - 0.0084 16.5 0.2 0.071 13.5 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORZ02970.1 - 0.019 15.0 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 ORZ02970.1 - 0.043 13.6 0.9 1.9 8.3 0.9 2.4 1 1 0 1 1 1 0 Bacterial dnaA protein DNA_pol3_delta PF06144.13 ORZ02970.1 - 0.053 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ABC_tran PF00005.27 ORZ02970.1 - 0.057 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter UvrA_inter PF17760.1 ORZ02970.1 - 0.076 13.1 1.6 3.7 7.6 1.8 2.3 1 1 1 2 2 2 0 UvrA interaction domain Chromo PF00385.24 ORZ02971.1 - 2e-12 46.8 6.8 2.9e-11 43.1 6.8 2.3 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 ORZ02971.1 - 6.9e-06 26.1 0.0 0.0044 17.1 0.0 2.8 3 0 0 3 3 3 2 Chromo shadow domain VirC1 PF07015.11 ORZ02971.1 - 0.19 11.0 0.3 0.33 10.2 0.1 1.4 2 0 0 2 2 2 0 VirC1 protein FG-GAP PF01839.23 ORZ02972.1 - 1.6e-21 76.1 8.5 1.9e-07 31.1 1.8 4.1 4 0 0 4 4 4 3 FG-GAP repeat Zn_dep_PLPC PF00882.18 ORZ02972.1 - 2e-16 60.5 1.4 3.9e-16 59.6 1.4 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 ORZ02972.1 - 4.5e-09 36.8 5.7 6.3e-06 26.7 2.2 3.2 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 ORZ02972.1 - 0.012 15.0 0.6 0.33 10.3 0.0 2.7 2 1 1 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Glyco_hydro_47 PF01532.20 ORZ02973.1 - 6e-117 391.3 0.0 6.8e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 ORZ02973.1 - 0.0096 14.5 0.0 0.091 11.2 0.0 2.0 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Pyridox_oxase_2 PF12766.7 ORZ02974.1 - 1.2e-27 96.4 0.0 2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ORZ02974.1 - 2e-08 34.3 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2070 PF09843.9 ORZ02976.1 - 0.066 11.5 1.3 0.07 11.4 1.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MerC PF03203.14 ORZ02976.1 - 0.15 12.5 5.4 0.2 12.1 5.4 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF2721 PF11026.8 ORZ02976.1 - 0.71 9.8 5.5 0.88 9.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) FAM176 PF14851.6 ORZ02976.1 - 3.1 7.5 4.1 0.71 9.5 0.1 1.8 1 1 1 2 2 2 0 FAM176 family COX4_pro_2 PF07835.12 ORZ02976.1 - 6.2 7.0 5.9 1 9.5 0.8 2.0 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2828 PF11443.8 ORZ02978.1 - 8.7e-198 658.4 4.5 1e-197 658.2 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) IBR PF01485.21 ORZ02979.1 - 1.6e-22 79.4 51.0 5.4e-12 45.7 4.8 4.5 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORZ02979.1 - 0.00094 19.0 9.6 0.00094 19.0 9.6 4.2 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORZ02979.1 - 0.0033 17.7 12.7 0.0033 17.7 12.7 3.8 2 1 1 3 3 3 2 Ring finger domain DUF746 PF05344.11 ORZ02979.1 - 0.15 12.0 0.1 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Vps51 PF08700.11 ORZ02980.1 - 3.8e-27 94.2 1.9 6.4e-27 93.5 0.4 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 ORZ02980.1 - 4.1e-21 75.6 2.3 6e-20 71.9 1.2 2.6 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 ORZ02980.1 - 2.6e-19 69.1 1.8 2.6e-19 69.1 1.8 1.7 2 0 0 2 2 2 1 Dor1-like family Vps54_N PF10475.9 ORZ02980.1 - 7.2e-11 41.9 1.0 7.2e-11 41.9 1.0 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 ORZ02980.1 - 3.3e-07 30.5 3.2 4e-07 30.3 0.2 2.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Zw10 PF06248.13 ORZ02980.1 - 2.4e-06 26.4 0.6 4.8e-06 25.4 0.6 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 COG2 PF06148.11 ORZ02980.1 - 6e-05 23.2 0.4 0.00069 19.7 0.1 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 ORZ02980.1 - 0.0011 18.0 0.7 0.0011 18.0 0.7 2.3 3 0 0 3 3 3 1 Vps53-like, N-terminal Sec8_exocyst PF04048.14 ORZ02980.1 - 0.016 15.1 2.5 0.046 13.6 0.1 3.1 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 ORZ02980.1 - 0.15 12.0 0.5 0.8 9.7 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II bZIP_1 PF00170.21 ORZ02980.1 - 0.22 11.6 0.5 13 6.0 0.1 2.9 2 0 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 ORZ02980.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.9 4 1 0 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 ORZ02980.1 - 0.25 11.6 2.2 1.1 9.5 0.0 3.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DASH_Duo1 PF08651.10 ORZ02980.1 - 0.67 9.8 3.4 32 4.4 0.8 4.0 4 0 0 4 4 4 0 DASH complex subunit Duo1 DUF948 PF06103.11 ORZ02980.1 - 0.82 10.0 4.7 2.9 8.2 0.3 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PhoU PF01895.19 ORZ02980.1 - 4.9 7.7 7.9 0.86 10.1 0.2 3.3 4 0 0 4 4 2 0 PhoU domain Baculo_PEP_C PF04513.12 ORZ02980.1 - 8.4 6.4 12.2 3.8 7.5 1.2 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C2H2_jaz PF12171.8 ORZ02981.1 - 8.5e-09 35.5 2.6 1.4e-08 34.8 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORZ02981.1 - 4.2e-08 33.3 2.2 6.6e-08 32.7 2.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORZ02981.1 - 0.0016 18.7 1.9 0.0031 17.8 1.9 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Peptidase_M60 PF13402.6 ORZ02981.1 - 0.0019 17.8 0.2 0.0021 17.6 0.2 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like zf-DBF PF07535.12 ORZ02981.1 - 0.029 14.5 0.4 0.053 13.6 0.4 1.4 1 0 0 1 1 1 0 DBF zinc finger DUF3347 PF11827.8 ORZ02981.1 - 0.036 14.2 3.7 0.043 14.0 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) zf-C2H2 PF00096.26 ORZ02981.1 - 0.091 13.3 0.3 0.18 12.3 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type OrsD PF12013.8 ORZ02981.1 - 0.21 12.0 3.6 0.33 11.4 2.9 1.6 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D FYDLN_acid PF09538.10 ORZ02981.1 - 0.74 10.5 4.8 1.1 10.0 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ctr PF04145.15 ORZ02981.1 - 2.3 8.8 4.5 2.7 8.6 4.0 1.3 1 1 0 1 1 1 0 Ctr copper transporter family CTU2 PF10288.9 ORZ02981.1 - 3.7 7.8 8.4 5.3 7.3 8.4 1.5 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 V-SNARE PF05008.15 ORZ02982.1 - 6.9e-21 74.4 6.5 2.8e-20 72.4 1.3 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORZ02982.1 - 2.5e-19 69.3 3.8 6.1e-19 68.1 1.7 2.4 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Ribosomal_S8 PF00410.19 ORZ02982.1 - 0.075 13.0 0.0 0.25 11.3 0.0 1.9 1 1 1 2 2 2 0 Ribosomal protein S8 RRF PF01765.19 ORZ02982.1 - 0.6 10.0 5.2 2 8.3 0.4 2.5 2 1 1 3 3 3 0 Ribosome recycling factor RRM_1 PF00076.22 ORZ02983.1 - 1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 ORZ02984.1 - 1.2e-15 57.3 26.8 7.8e-09 35.5 11.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 ORZ02987.1 - 4.3e-55 186.9 0.0 5.3e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02987.1 - 4.4e-21 75.3 0.0 7.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORZ02987.1 - 0.00032 20.7 0.1 0.0017 18.4 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 ORZ02987.1 - 0.0096 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Choline_kinase PF01633.20 ORZ02987.1 - 0.011 15.4 0.1 0.027 14.0 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Gpr1_Fun34_YaaH PF01184.19 ORZ02988.1 - 1.9e-34 119.1 19.6 2.3e-34 118.8 19.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ABC2_membrane_4 PF12730.7 ORZ02988.1 - 2.8 7.9 12.2 0.3 11.0 6.0 2.3 2 1 1 3 3 3 0 ABC-2 family transporter protein TPR_12 PF13424.6 ORZ02989.1 - 0.0097 16.2 1.0 1.1 9.6 0.5 3.1 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ02989.1 - 0.18 12.1 9.5 7.1 7.1 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ02989.1 - 0.31 12.0 2.8 11 7.2 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ02989.1 - 3.8 7.9 10.2 17 5.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat RICTOR_N PF14664.6 ORZ02990.1 - 1.7e-100 336.7 0.3 1.7e-100 336.7 0.3 2.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 ORZ02990.1 - 1.5e-37 128.3 2.4 2.6e-36 124.3 0.3 3.2 3 0 0 3 3 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 ORZ02990.1 - 1.7e-36 124.1 1.7 7.2e-31 106.0 0.0 5.6 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 ORZ02990.1 - 3e-33 113.9 0.9 5e-29 100.3 0.0 5.1 5 1 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 ORZ02990.1 - 1.3e-05 25.2 1.3 4.9e-05 23.4 1.3 2.1 1 0 0 1 1 1 1 Hr1 repeat Adaptin_N PF01602.20 ORZ02990.1 - 0.0032 16.1 5.0 2.2 6.7 0.3 3.8 3 1 0 3 3 3 2 Adaptin N terminal region Proteasom_PSMB PF10508.9 ORZ02990.1 - 0.0066 15.0 1.8 0.087 11.3 0.2 3.2 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 ORZ02990.1 - 0.013 15.9 4.9 0.16 12.3 0.1 4.6 4 1 1 5 5 5 0 HEAT repeats HEAT PF02985.22 ORZ02990.1 - 0.021 15.1 0.6 1.3e+02 3.3 0.1 5.1 5 0 0 5 5 4 0 HEAT repeat Arm PF00514.23 ORZ02990.1 - 0.028 14.4 12.7 2.3 8.4 0.0 6.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 ORZ02990.1 - 0.08 13.1 2.8 0.17 12.1 0.0 3.2 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3412 PF11892.8 ORZ02990.1 - 0.26 11.4 1.6 5 7.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3412) Ribosomal_L11_N PF03946.14 ORZ02991.1 - 9.2e-23 79.9 0.1 2.1e-22 78.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORZ02991.1 - 8e-19 67.9 0.1 1.2e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ADH_zinc_N PF00107.26 ORZ02992.1 - 3.1e-27 95.1 0.1 5.6e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ02992.1 - 1.9e-13 51.6 0.0 5.2e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORZ02992.1 - 8.9e-10 38.4 0.2 7.9e-09 35.4 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORZ02992.1 - 7.5e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Sugar_tr PF00083.24 ORZ02993.1 - 3.1e-99 332.9 20.4 3.8e-99 332.6 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ02993.1 - 2.1e-28 99.3 30.5 2.1e-19 69.7 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORZ02993.1 - 0.0018 16.9 5.6 0.0018 16.9 5.6 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 ORZ02993.1 - 0.7 8.2 10.3 0.055 11.9 5.5 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 ORZ02994.1 - 2.1e-68 230.5 0.0 4.3e-68 229.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ02994.1 - 1.2e-50 172.2 0.0 2e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 ORZ02994.1 - 8.4e-15 54.9 0.1 1.5e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 ORZ02994.1 - 2.1e-05 24.3 9.8 3.8e-05 23.5 9.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 ORZ02994.1 - 0.0018 17.7 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like CDC24 PF06395.11 ORZ02994.1 - 0.0041 17.3 0.0 0.0092 16.2 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin Zn_ribbon_17 PF17120.5 ORZ02994.1 - 0.0058 16.2 8.2 0.011 15.3 8.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type CAMSAP_CH PF11971.8 ORZ02994.1 - 0.0064 16.3 0.1 0.018 14.8 0.1 1.8 1 1 0 1 1 1 1 CAMSAP CH domain RIO1 PF01163.22 ORZ02994.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.7 1 1 0 1 1 1 0 RIO1 family TonB_N PF16031.5 ORZ02994.1 - 0.48 10.9 8.5 0.21 12.1 0.2 3.1 3 0 0 3 3 3 0 TonB polyproline region GPI-anchored PF10342.9 ORZ02995.1 - 1.4e-13 51.4 4.2 1.4e-13 51.4 4.2 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zeta_toxin PF06414.12 ORZ02996.1 - 6.5e-05 22.3 0.0 0.028 13.7 0.0 3.0 2 1 1 3 3 3 2 Zeta toxin AAA_18 PF13238.6 ORZ02996.1 - 0.0017 18.9 0.2 0.0084 16.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORZ02996.1 - 0.036 14.2 0.1 0.21 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORZ02996.1 - 0.048 13.9 0.1 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORZ02996.1 - 0.069 13.5 0.2 0.16 12.4 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain HA2 PF04408.23 ORZ02997.1 - 2.4e-16 60.0 0.0 2.4e-16 60.0 0.0 2.9 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORZ02997.1 - 3.5e-14 53.1 0.0 9.5e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORZ02997.1 - 7.7e-09 35.6 1.7 1.4e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 ORZ02997.1 - 1.5e-07 31.7 0.0 3.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 ORZ02997.1 - 2.2e-06 28.0 1.3 9.5e-05 22.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 ORZ02997.1 - 0.0035 17.9 0.0 0.0035 17.9 0.0 3.6 4 0 0 4 4 2 1 AAA domain Rad17 PF03215.15 ORZ02997.1 - 0.026 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 ORZ02997.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 ORZ02997.1 - 0.037 13.5 0.0 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 ORZ02997.1 - 0.06 12.7 0.6 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 ORZ02997.1 - 0.083 13.3 0.1 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORZ02997.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 ORZ02997.1 - 0.2 11.4 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ASXH PF13919.6 ORZ02997.1 - 0.21 11.6 7.0 0.025 14.6 1.3 2.3 2 0 0 2 2 2 0 Asx homology domain Aa_trans PF01490.18 ORZ02998.1 - 1.4e-63 215.0 24.8 1.7e-63 214.8 24.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA_27 PF13514.6 ORZ03000.1 - 0.06 12.9 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Hamartin PF04388.12 ORZ03000.1 - 2.9 6.5 13.9 3.4 6.2 13.9 1.0 1 0 0 1 1 1 0 Hamartin protein CotH PF08757.11 ORZ03002.1 - 3.5e-38 131.9 1.3 6.5e-37 127.8 1.3 2.1 1 1 0 1 1 1 1 CotH kinase protein zf-CCCH_4 PF18044.1 ORZ03003.1 - 2.9e-13 49.3 7.7 9.9e-07 28.4 1.2 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORZ03003.1 - 3.3e-11 42.9 17.3 1.8e-06 27.8 3.6 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORZ03003.1 - 3.5e-11 42.7 8.9 1e-05 25.3 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORZ03003.1 - 1.9e-09 38.2 6.1 0.0002 22.0 0.2 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 ORZ03003.1 - 6.1e-06 26.4 1.2 1.1e-05 25.6 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORZ03003.1 - 0.006 17.0 14.9 0.014 15.9 2.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger SRP40_C PF05022.12 ORZ03004.1 - 2.4e-28 98.8 2.3 2.7e-28 98.6 2.3 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.11 ORZ03005.1 - 0.0002 21.2 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 LisH PH PF00169.29 ORZ03006.1 - 0.0032 18.0 0.0 0.0085 16.6 0.0 1.8 1 0 0 1 1 1 1 PH domain LRR_6 PF13516.6 ORZ03006.1 - 0.064 13.3 0.2 0.064 13.3 0.2 6.6 9 0 0 9 9 9 0 Leucine Rich repeat Arrestin_N PF00339.29 ORZ03009.1 - 2.1e-07 31.1 1.6 0.0015 18.6 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORZ03009.1 - 3.4e-06 27.6 1.8 3.7e-05 24.2 2.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain AA_permease_2 PF13520.6 ORZ03010.1 - 1e-65 222.2 52.5 1.3e-65 222.0 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORZ03010.1 - 6.7e-27 94.2 41.6 9.7e-27 93.7 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease HLH PF00010.26 ORZ03011.1 - 2.9e-05 23.9 6.5 2.9e-05 23.9 6.5 2.5 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Gemini_AC4_5 PF04807.12 ORZ03011.1 - 0.059 13.1 0.2 0.083 12.6 0.2 1.2 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Rootletin PF15035.6 ORZ03012.1 - 0.0048 17.0 0.1 0.0053 16.8 0.1 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion IATP PF04568.12 ORZ03012.1 - 0.011 16.1 0.9 0.018 15.4 0.9 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP HLH PF00010.26 ORZ03012.1 - 0.027 14.4 1.0 0.082 12.9 0.0 2.0 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain zf-dskA_traR PF01258.17 ORZ03012.1 - 0.06 13.3 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Use1 PF09753.9 ORZ03012.1 - 0.11 12.1 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 ABC1 PF03109.16 ORZ03013.1 - 2.9e-33 114.5 0.0 4.6e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 ORZ03013.1 - 5.4e-05 22.9 0.2 0.0015 18.2 0.0 2.5 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.25 ORZ03013.1 - 0.0024 17.3 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 ORZ03013.1 - 0.003 17.5 0.5 0.061 13.2 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 ORZ03014.1 - 2e-39 135.8 0.0 2.4e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORZ03014.1 - 0.00011 21.6 0.1 0.00094 18.5 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORZ03014.1 - 0.00014 21.5 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 ORZ03014.1 - 0.00014 21.6 0.1 0.00016 21.3 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORZ03014.1 - 0.00016 22.1 0.0 0.038 14.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORZ03014.1 - 0.0024 16.7 0.0 0.004 15.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 ORZ03014.1 - 0.0031 17.7 0.0 0.0078 16.4 0.0 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 ORZ03014.1 - 0.033 14.8 0.0 0.065 13.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ORZ03014.1 - 0.034 14.0 0.0 0.15 12.0 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 ORZ03014.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NTP_transferase PF00483.23 ORZ03016.1 - 1.8e-09 37.6 0.0 0.00072 19.2 0.0 2.8 1 1 1 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.24 ORZ03016.1 - 2.6e-08 33.3 12.2 0.002 17.8 1.1 4.1 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 ORZ03016.1 - 6.8e-06 24.5 2.1 9.7e-06 24.0 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 ORZ03016.1 - 0.00015 22.2 0.0 0.00048 20.5 0.0 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 ORZ03016.1 - 0.028 13.4 1.8 0.054 12.4 1.8 1.5 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 ORZ03016.1 - 0.32 10.8 4.9 4.8 7.0 3.4 3.1 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4452 PF14618.6 ORZ03017.1 - 0.0015 18.4 13.1 0.083 12.8 0.9 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4452) KilA-N PF04383.13 ORZ03019.1 - 0.0019 18.0 0.0 0.0081 16.0 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain MIT PF04212.18 ORZ03020.1 - 2.6e-07 30.6 0.2 5.2e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF4716 PF15837.5 ORZ03020.1 - 0.076 13.1 0.9 0.32 11.1 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) Inhibitor_I78 PF11720.8 ORZ03021.1 - 6.3e-09 35.8 0.1 1e-08 35.1 0.1 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORZ03021.1 - 4.3e-05 24.1 0.1 7.4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Potato inhibitor I family zf-C2H2 PF00096.26 ORZ03022.1 - 9.5e-16 57.3 27.4 2.4e-05 24.5 0.3 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03022.1 - 4.9e-10 39.4 25.6 0.0046 17.7 0.5 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORZ03022.1 - 1.7e-05 24.7 0.3 1.7e-05 24.7 0.3 3.9 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.7 ORZ03022.1 - 5.5e-05 23.4 4.0 0.00067 20.0 0.4 4.6 5 0 0 5 5 5 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORZ03022.1 - 0.00012 22.7 14.5 1.9 9.2 2.0 4.8 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-Di19 PF05605.12 ORZ03022.1 - 0.00019 21.7 24.1 0.0023 18.2 0.9 3.9 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 ORZ03022.1 - 0.00068 19.9 5.0 0.00068 19.9 5.0 3.4 2 2 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORZ03022.1 - 0.0036 17.5 0.2 0.0036 17.5 0.2 5.2 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORZ03022.1 - 0.42 11.1 0.1 0.42 11.1 0.1 5.3 6 0 0 6 6 5 0 Zinc-finger double domain zf_Hakai PF18408.1 ORZ03022.1 - 5.6 6.7 10.4 12 5.7 0.1 3.8 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-RAG1 PF10426.9 ORZ03022.1 - 7.1 6.9 11.0 13 6.0 0.3 3.8 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain Ribosomal_L18 PF17135.4 ORZ03024.1 - 2.9e-90 300.7 4.6 3.2e-90 300.6 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORZ03024.1 - 1.3 9.7 4.3 0.28 11.9 0.3 2.1 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DEAD PF00270.29 ORZ03025.1 - 1.1e-43 149.1 0.1 2.5e-43 147.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ03025.1 - 4.8e-28 97.7 1.0 8.8e-27 93.6 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Tyr-DNA_phospho PF06087.12 ORZ03026.1 - 1.4e-66 225.1 0.0 1.8e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 ORZ03026.1 - 4.1e-06 26.7 0.1 0.079 12.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.20 ORZ03026.1 - 4.7e-05 23.0 6.3 0.00076 19.2 2.0 2.4 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF1358 PF07096.11 ORZ03027.1 - 2.5e-06 27.4 0.8 7.9e-06 25.8 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1358) zf-C2H2 PF00096.26 ORZ03028.1 - 9.4e-15 54.2 10.1 1.2e-07 31.7 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ03028.1 - 4.2e-08 33.3 15.1 1.8e-06 28.1 4.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_aberr PF17017.5 ORZ03028.1 - 2.8e-06 27.6 1.1 0.0095 16.1 0.3 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ORZ03028.1 - 4.7e-06 27.0 15.2 0.0013 19.4 1.5 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.7 ORZ03028.1 - 0.0041 17.5 5.2 0.72 10.3 2.6 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORZ03028.1 - 0.0041 17.4 5.3 0.28 11.5 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORZ03028.1 - 0.008 16.8 2.4 0.23 12.1 0.1 2.3 1 1 1 2 2 2 1 FOXP coiled-coil domain DUF2083 PF09856.9 ORZ03028.1 - 0.034 14.0 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Ogr_Delta PF04606.12 ORZ03028.1 - 0.053 13.5 0.3 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_8 PF15909.5 ORZ03028.1 - 0.11 12.8 3.9 0.087 13.1 2.1 1.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 ORZ03028.1 - 0.2 12.0 5.0 0.4 11.0 1.3 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CHORD PF04968.12 ORZ03028.1 - 0.63 10.8 5.3 2.5 8.9 0.3 2.4 1 1 1 2 2 2 0 CHORD zf-C2H2_6 PF13912.6 ORZ03028.1 - 1.7 8.8 10.0 0.3 11.1 1.5 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORZ03028.1 - 8.6 6.2 16.8 1.1 9.1 1.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HMG_box PF00505.19 ORZ03029.1 - 9.3e-13 48.4 1.2 9.3e-13 48.4 1.2 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ03029.1 - 9.7e-11 42.1 1.4 9.7e-11 42.1 1.4 2.3 1 1 1 2 2 2 1 HMG-box domain SAM_1 PF00536.30 ORZ03029.1 - 5.3e-08 33.2 0.1 1.8e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORZ03029.1 - 1.8e-06 27.9 0.0 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 ORZ03029.1 - 5.2e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Rotamase PF00639.21 ORZ03029.1 - 0.056 14.4 0.6 0.73 10.8 0.1 2.5 2 1 0 2 2 2 0 PPIC-type PPIASE domain Rpr2 PF04032.16 ORZ03030.1 - 7.2e-14 51.8 0.1 8.2e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain WWE PF02825.20 ORZ03031.1 - 0.014 15.9 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 WWE domain PMT PF02366.18 ORZ03032.1 - 4.9e-80 268.6 19.5 8.7e-80 267.8 19.5 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORZ03032.1 - 6.4e-62 208.7 5.6 6.4e-62 208.7 5.6 3.3 2 1 1 4 4 4 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORZ03032.1 - 9.5e-13 48.4 1.8 3.5e-12 46.5 1.7 1.8 1 1 0 1 1 1 1 MIR domain WD40 PF00400.32 ORZ03033.1 - 8.4e-28 96.1 7.4 1.9e-06 28.5 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat PRP4 PF08799.11 ORZ03033.1 - 1.2e-12 47.2 4.1 1.2e-12 47.2 4.1 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 ORZ03033.1 - 8.4e-10 38.8 0.0 0.092 13.1 0.0 4.1 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORZ03033.1 - 0.00044 19.3 0.1 1.5 7.7 0.0 3.3 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORZ03033.1 - 0.00065 19.6 0.0 0.013 15.4 0.0 2.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Filo_glycop PF01611.16 ORZ03033.1 - 0.057 12.4 0.0 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Filovirus glycoprotein WD40 PF00400.32 ORZ03034.1 - 0.00017 22.3 0.2 0.007 17.2 0.4 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat Nebulin PF00880.18 ORZ03034.1 - 0.18 11.7 0.5 0.28 11.1 0.5 1.2 1 0 0 1 1 1 0 Nebulin repeat Ribosomal_L31e PF01198.19 ORZ03035.1 - 5.5e-41 138.7 1.5 6.7e-41 138.4 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 ORZ03035.1 - 0.082 13.0 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Nuc_sug_transp PF04142.15 ORZ03036.1 - 3.1e-105 351.8 23.8 1.1e-65 221.9 4.6 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 ORZ03036.1 - 0.00072 19.7 5.7 0.00072 19.7 5.7 3.9 3 2 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 ORZ03036.1 - 0.0014 17.9 14.8 0.019 14.2 0.1 2.8 2 1 0 2 2 2 2 UAA transporter family Cas3_C PF18395.1 ORZ03036.1 - 0.092 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Cas3 C-terminal domain MFAP1 PF06991.11 ORZ03037.1 - 7.8e-70 235.1 28.1 7.8e-70 235.1 28.1 3.4 1 1 2 3 3 3 1 Microfibril-associated/Pre-mRNA processing Exo_endo_phos PF03372.23 ORZ03038.1 - 1.3e-23 83.8 0.1 1.6e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ORZ03038.1 - 0.0024 17.7 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Cyclin_N PF00134.23 ORZ03040.1 - 1.8e-05 24.5 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORZ03040.1 - 0.0095 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin zf-primase PF09329.11 ORZ03041.1 - 4.5e-08 32.8 0.3 8.5e-08 31.9 0.3 1.5 1 0 0 1 1 1 1 Primase zinc finger Eapp_C PF10238.9 ORZ03043.1 - 4.9e-42 143.5 14.8 4.4e-31 108.0 5.6 2.0 1 1 1 2 2 2 2 E2F-associated phosphoprotein VASt PF16016.5 ORZ03043.1 - 0.016 15.7 0.4 0.018 15.4 0.4 1.1 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain Yippee-Mis18 PF03226.14 ORZ03043.1 - 0.033 14.4 4.7 0.052 13.8 4.7 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3997 PF13162.6 ORZ03043.1 - 0.043 14.1 0.8 0.067 13.5 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3997) MecA_N PF05223.11 ORZ03043.1 - 0.16 12.2 0.3 0.16 12.2 0.3 1.6 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain C1_4 PF07975.12 ORZ03043.1 - 0.39 11.0 6.5 3.3 8.0 0.7 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_10 PF10058.9 ORZ03043.1 - 0.63 9.8 0.0 0.63 9.8 0.0 2.8 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein UAA PF08449.11 ORZ03044.1 - 1e-84 284.3 10.3 1.3e-84 284.0 10.3 1.0 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 ORZ03044.1 - 0.00076 18.5 1.0 0.00076 18.5 1.0 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 ORZ03044.1 - 0.0022 17.3 8.7 0.01 15.1 1.3 2.1 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport SLC35F PF06027.12 ORZ03044.1 - 0.0074 15.8 7.7 0.094 12.2 1.2 2.2 2 0 0 2 2 2 2 Solute carrier family 35 EamA PF00892.20 ORZ03044.1 - 1.8 8.8 28.2 13 5.9 13.1 3.4 2 2 0 2 2 2 0 EamA-like transporter family LCM PF04072.14 ORZ03045.1 - 5.9e-25 88.3 0.0 3.1e-24 86.0 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase YscJ_FliF_C PF08345.11 ORZ03046.1 - 0.062 13.6 1.6 0.14 12.5 1.6 1.6 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Polyketide_cyc2 PF10604.9 ORZ03046.1 - 0.097 12.9 0.2 0.3 11.4 0.2 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Rad21_Rec8_N PF04825.13 ORZ03047.1 - 1.2e-27 96.3 0.0 3.7e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORZ03047.1 - 3.1e-12 45.6 0.1 6.8e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein FNIP_N PF14636.6 ORZ03047.1 - 7.3 7.5 9.7 1.9 9.5 5.0 2.3 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus FKBP_C PF00254.28 ORZ03048.1 - 1.9e-33 114.7 0.0 2.8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-RING_2 PF13639.6 ORZ03049.1 - 0.00015 22.0 7.7 0.00015 22.0 7.7 1.9 2 0 0 2 2 2 1 Ring finger domain FYVE_2 PF02318.16 ORZ03049.1 - 0.00021 21.5 1.8 0.00051 20.2 1.8 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 ORZ03049.1 - 0.0022 17.8 2.2 0.0022 17.8 2.2 2.5 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 ORZ03049.1 - 0.0033 17.3 7.0 0.008 16.0 7.0 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.6 ORZ03049.1 - 0.019 14.9 6.5 0.019 14.9 6.5 1.9 2 0 0 2 2 2 0 zinc-RING finger domain SWIM PF04434.17 ORZ03049.1 - 0.036 13.7 1.4 0.086 12.5 1.4 1.7 1 0 0 1 1 1 0 SWIM zinc finger zf-RING_UBOX PF13445.6 ORZ03049.1 - 0.043 13.9 4.5 0.11 12.6 4.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 ORZ03049.1 - 0.08 13.0 1.8 0.23 11.5 1.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon PHD_4 PF16866.5 ORZ03049.1 - 0.22 11.6 5.7 2.4 8.3 5.6 2.6 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 ORZ03049.1 - 0.41 10.6 9.8 0.08 12.9 5.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 ORZ03049.1 - 0.79 9.9 7.7 1.9 8.7 7.7 1.7 1 0 0 1 1 1 0 RING-variant domain YihI PF04220.12 ORZ03049.1 - 2.7 7.7 6.5 6.9 6.4 6.5 1.7 1 0 0 1 1 1 0 Der GTPase activator (YihI) AhpC-TSA PF00578.21 ORZ03050.1 - 2.6e-31 108.1 0.0 3.2e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORZ03050.1 - 2.1e-14 53.5 0.0 2.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORZ03050.1 - 8.1e-11 41.6 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Methyltransf_23 PF13489.6 ORZ03051.1 - 1.3e-09 38.1 0.0 3e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ03051.1 - 2e-06 28.4 0.0 1.7e-05 25.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ03051.1 - 1.1e-05 26.0 0.0 4.2e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03051.1 - 2.1e-05 25.1 0.0 0.00054 20.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORZ03051.1 - 2.2e-05 24.0 0.0 7.7e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.6 ORZ03051.1 - 6.3e-05 22.8 0.0 0.00032 20.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORZ03051.1 - 0.036 14.1 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 ORZ03051.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 ORZ03051.1 - 0.14 11.5 0.0 2 7.7 0.0 2.2 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aminotran_5 PF00266.19 ORZ03052.1 - 2.8e-34 118.7 0.0 3.7e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 ORZ03052.1 - 0.0052 16.8 0.1 0.021 14.9 0.1 2.0 2 0 0 2 2 2 1 B12 binding domain KR PF08659.10 ORZ03052.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 KR domain PG_binding_2 PF08823.11 ORZ03052.1 - 0.11 12.8 0.1 24 5.3 0.0 2.7 3 0 0 3 3 3 0 Putative peptidoglycan binding domain MFS_1_like PF12832.7 ORZ03053.1 - 1.1e-58 199.0 9.9 1.4e-58 198.6 9.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 ORZ03053.1 - 2.4e-18 66.2 51.9 6.7e-12 45.0 27.1 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 ORZ03053.1 - 9.8e-06 24.8 6.4 9.8e-06 24.8 6.4 2.3 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_2 PF13347.6 ORZ03053.1 - 0.00011 20.9 5.4 0.00011 20.9 5.4 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Cyclin_N PF00134.23 ORZ03055.1 - 1.8e-05 24.5 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORZ03055.1 - 6.1e-05 23.4 0.0 0.00025 21.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin Sugar_tr PF00083.24 ORZ03056.1 - 1.4e-101 340.6 22.4 2.1e-101 340.0 22.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ03056.1 - 7.2e-23 81.1 35.8 1.5e-20 73.4 20.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORZ03056.1 - 0.0014 17.1 2.6 0.0025 16.3 2.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM132D_C PF15706.5 ORZ03056.1 - 0.99 9.2 0.0 0.99 9.2 0.0 2.5 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Dynamitin PF04912.14 ORZ03057.1 - 1.5e-38 133.2 2.1 2e-38 132.7 2.1 1.1 1 0 0 1 1 1 1 Dynamitin BLOC1_2 PF10046.9 ORZ03057.1 - 0.12 12.7 2.9 11 6.4 0.1 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LidA_Long_CC PF18641.1 ORZ03057.1 - 1.1 9.3 3.8 0.8 9.7 0.8 2.1 3 0 0 3 3 3 0 LidA long coiled-coil domain Dynamitin PF04912.14 ORZ03058.1 - 6.6e-30 104.7 13.2 8.3e-30 104.4 13.2 1.1 1 0 0 1 1 1 1 Dynamitin PTR PF12789.7 ORZ03058.1 - 0.015 15.3 0.6 0.067 13.3 0.2 2.1 2 0 0 2 2 2 0 Phage tail repeat like Baculo_PEP_C PF04513.12 ORZ03058.1 - 0.041 13.9 1.7 0.13 12.4 1.7 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 ORZ03058.1 - 0.09 13.3 5.9 1.5 9.4 4.8 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Allexi_40kDa PF05549.11 ORZ03058.1 - 0.31 10.5 2.9 0.52 9.8 2.9 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3573 PF12097.8 ORZ03058.1 - 0.44 9.3 2.3 0.59 8.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1993 PF09351.10 ORZ03058.1 - 0.78 9.9 2.9 3.6 7.7 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Spc24 PF08286.11 ORZ03058.1 - 5.3 7.3 11.6 2.9 8.2 5.1 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlxA PF14282.6 ORZ03058.1 - 5.5 7.0 9.5 0.94 9.5 5.0 2.1 2 1 0 2 2 2 0 FlxA-like protein HECT PF00632.25 ORZ03059.1 - 1.4e-74 251.3 0.0 2.3e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SDA1 PF05285.12 ORZ03059.1 - 0.0025 17.3 6.8 0.0025 17.3 6.8 4.5 3 1 1 4 4 4 2 SDA1 TGT_C1 PF14809.6 ORZ03061.1 - 0.11 12.9 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation SPX PF03105.19 ORZ03061.1 - 0.11 12.3 2.6 0.14 12.1 2.6 1.1 1 0 0 1 1 1 0 SPX domain CIA30 PF08547.12 ORZ03062.1 - 3.8e-46 157.0 0.0 4.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 ORZ03062.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain TBCA PF02970.16 ORZ03063.1 - 1.4e-25 89.4 7.9 1.6e-25 89.2 7.7 1.2 1 1 0 1 1 1 1 Tubulin binding cofactor A Grg1 PF11034.8 ORZ03063.1 - 0.019 15.2 1.3 0.026 14.7 0.9 1.5 1 1 0 1 1 1 0 Glucose-repressible protein Grg1 Spc7 PF08317.11 ORZ03063.1 - 0.027 13.4 3.2 0.021 13.7 2.0 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Phage_30_3 PF08010.11 ORZ03063.1 - 0.037 13.8 0.2 0.045 13.6 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 DJ-1_PfpI PF01965.24 ORZ03065.1 - 5.7e-45 153.1 0.4 6.7e-45 152.9 0.4 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 ORZ03065.1 - 0.0036 16.9 0.2 0.0054 16.4 0.2 1.5 1 1 0 1 1 1 1 C-terminal domain found in long catalases ThiJ_like PF17124.5 ORZ03065.1 - 0.007 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 ORZ03065.1 - 0.075 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain VWA PF00092.28 ORZ03065.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF2124 PF09897.9 ORZ03065.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2124) Band_7 PF01145.25 ORZ03066.1 - 3.5e-23 82.5 5.0 4.7e-23 82.1 5.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Arginase PF00491.21 ORZ03067.1 - 5.5e-88 295.1 0.0 7.2e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ORZ03067.1 - 0.0034 17.6 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain DNA_pol_delta_4 PF04081.13 ORZ03069.1 - 9e-21 74.6 6.2 3.7e-20 72.6 6.2 1.8 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 TB2_DP1_HVA22 PF03134.19 ORZ03070.1 - 1.5e-19 69.7 4.1 3.6e-19 68.5 4.1 1.7 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ABC_membrane PF00664.23 ORZ03070.1 - 0.022 14.4 0.4 0.039 13.6 0.4 1.5 1 1 0 1 1 1 0 ABC transporter transmembrane region Cellulase PF00150.18 ORZ03071.1 - 1.4e-15 57.5 0.0 5e-11 42.6 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORZ03071.1 - 1e-10 42.0 0.2 2.4e-10 40.8 0.2 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain DUF4529 PF15032.6 ORZ03071.1 - 1.7 7.6 4.8 18 4.3 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4529) Exo70 PF03081.15 ORZ03072.1 - 2.9e-83 280.0 0.2 4.3e-83 279.4 0.2 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit SLR1-BP PF07333.12 ORZ03073.1 - 0.00036 20.9 7.8 0.00046 20.6 7.8 1.1 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Gamma-thionin PF00304.20 ORZ03073.1 - 0.0062 16.8 7.5 0.008 16.4 7.5 1.2 1 0 0 1 1 1 1 Gamma-thionin family PX PF00787.24 ORZ03074.1 - 6e-22 77.8 0.5 3.6e-21 75.2 0.1 2.2 2 0 0 2 2 2 1 PX domain PCNA_N PF00705.18 ORZ03075.1 - 4.1e-54 181.7 2.3 4.1e-54 181.7 2.3 2.0 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ORZ03075.1 - 3.3e-47 159.8 0.2 5.5e-47 159.1 0.2 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 ORZ03075.1 - 6e-09 35.4 1.3 2.7e-07 30.0 1.3 2.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 ORZ03075.1 - 2.3e-08 33.8 0.0 2.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 ORZ03075.1 - 0.0013 17.9 0.1 0.012 14.8 0.0 2.0 1 1 1 2 2 2 1 Hus1-like protein DNA_pol3_beta_3 PF02768.15 ORZ03075.1 - 0.01 15.7 1.7 0.06 13.2 0.4 2.6 2 1 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Melibiase PF02065.18 ORZ03077.1 - 1.4e-16 60.4 0.1 2.5e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.26 ORZ03077.1 - 2.3e-05 23.8 0.2 3.6e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5513 PF17632.2 ORZ03077.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5513) Mito_carr PF00153.27 ORZ03078.1 - 1.2e-67 223.8 8.2 2.9e-22 78.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 ORZ03078.1 - 4.2e-16 57.4 4.8 0.00051 19.8 0.6 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 ORZ03078.1 - 5.2e-16 58.8 1.7 4.9e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORZ03078.1 - 1.3e-14 52.5 2.2 1.1e-05 24.6 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORZ03078.1 - 3.4e-11 42.8 0.3 0.00024 20.9 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORZ03078.1 - 1.1e-07 31.0 1.0 0.00095 18.6 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 ORZ03078.1 - 9.7e-06 25.3 0.3 0.00098 18.9 0.0 3.1 2 2 1 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 ORZ03078.1 - 0.00011 22.5 0.1 0.67 10.3 0.2 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Serine_protease PF18405.1 ORZ03078.1 - 0.014 14.6 0.7 7.8 5.6 0.0 2.9 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Cadherin_C PF01049.17 ORZ03078.1 - 0.04 14.2 0.1 0.098 13.0 0.1 1.6 1 1 1 2 2 2 0 Cadherin cytoplasmic region EF-hand_4 PF12763.7 ORZ03078.1 - 0.062 13.3 0.5 1.3 9.0 0.2 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 ORZ03078.1 - 0.16 12.4 0.0 0.71 10.3 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain MFS_1 PF07690.16 ORZ03079.1 - 1.9e-35 122.4 27.2 1.9e-35 122.4 27.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TMIE PF16038.5 ORZ03079.1 - 0.17 11.7 1.8 0.34 10.8 1.0 2.0 1 1 0 1 1 1 0 TMIE protein DUF4231 PF14015.6 ORZ03079.1 - 1.1 9.8 4.7 0.71 10.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4064 PF13273.6 ORZ03079.1 - 2.3 8.6 22.0 13 6.1 0.7 4.7 2 2 1 3 3 3 0 Protein of unknown function (DUF4064) MFS_1 PF07690.16 ORZ03080.1 - 1.5e-39 135.9 24.2 1.5e-39 135.9 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORZ03080.1 - 1.8e-06 27.5 3.6 1.8e-06 27.5 3.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF5353 PF17304.2 ORZ03080.1 - 0.0036 17.0 1.7 0.011 15.4 1.7 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Phage_holin_8 PF16931.5 ORZ03080.1 - 0.07 13.1 0.8 0.18 11.8 0.8 1.7 1 0 0 1 1 1 0 Putative phage holin MYEOV2 PF15004.6 ORZ03081.1 - 0.00057 20.3 4.3 0.0012 19.2 4.0 1.8 1 1 0 1 1 1 1 Myeloma-overexpressed-like Metallophos PF00149.28 ORZ03082.1 - 5e-11 43.5 0.4 9.3e-11 42.6 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Far-17a_AIG1 PF04750.14 ORZ03083.1 - 0.0095 15.3 27.3 0.013 14.8 27.3 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein bZIP_1 PF00170.21 ORZ03084.1 - 1.4e-06 28.3 1.7 2.6e-06 27.4 1.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORZ03084.1 - 5.8e-06 26.3 1.5 8.9e-06 25.7 1.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF2856 PF11043.8 ORZ03084.1 - 0.02 15.0 0.1 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Methyltransf_25 PF13649.6 ORZ03085.1 - 6.8e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03085.1 - 1.2e-14 54.7 0.0 2.5e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03085.1 - 4.6e-11 42.7 0.0 7.3e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ03085.1 - 5.8e-11 42.5 0.0 8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ03085.1 - 2.3e-10 40.2 0.0 1.7e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORZ03085.1 - 4.8e-10 40.1 0.0 1.1e-09 38.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORZ03085.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 ORZ03085.1 - 1.2e-05 24.8 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ORZ03085.1 - 0.00028 20.4 0.0 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 ORZ03085.1 - 0.0016 18.5 0.0 0.0043 17.2 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.18 ORZ03085.1 - 0.0041 16.6 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 ORZ03085.1 - 0.0063 15.8 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORZ03085.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 ORZ03085.1 - 0.11 11.0 0.0 0.67 8.4 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cys_Met_Meta_PP PF01053.20 ORZ03086.1 - 1.2e-59 201.8 0.0 1.4e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TMEM234 PF10639.9 ORZ03088.1 - 4.4e-39 133.1 0.7 5.1e-39 132.9 0.7 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 ORZ03088.1 - 0.0001 22.5 4.8 0.00064 19.9 2.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family Cyclin_N PF00134.23 ORZ03089.1 - 3.2e-14 52.8 0.1 4.6e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 ORZ03089.1 - 0.00028 20.9 0.1 0.1 12.6 0.0 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORZ03089.1 - 0.011 15.8 0.3 0.066 13.3 0.0 2.2 2 1 0 2 2 2 0 Cyclin, C-terminal domain Mem_trans PF03547.18 ORZ03090.1 - 2.1e-44 151.5 7.3 3.3e-44 150.8 7.3 1.3 1 0 0 1 1 1 1 Membrane transport protein Dynein_light PF01221.18 ORZ03090.1 - 2.1e-26 92.0 0.4 4e-26 91.1 0.4 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 Arteri_GP4 PF02497.15 ORZ03090.1 - 0.039 14.1 0.3 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Arterivirus glycoprotein DUF3464 PF11947.8 ORZ03090.1 - 0.1 12.4 0.8 5.2 6.8 0.7 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Homeobox_KN PF05920.11 ORZ03091.1 - 1.2e-18 66.7 3.5 1.4e-18 66.5 1.4 2.3 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 ORZ03091.1 - 4.7e-08 32.8 0.3 1e-07 31.7 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 ORZ03092.1 - 7.3e-31 107.5 0.0 1.6e-30 106.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.6 ORZ03092.1 - 3.5e-20 71.8 36.6 8.8e-10 38.6 0.0 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORZ03092.1 - 4e-17 61.8 12.4 3.1e-06 27.0 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 ORZ03092.1 - 5.3e-13 48.3 23.3 0.00091 18.8 0.0 5.6 6 0 0 6 6 5 4 Kelch motif Kelch_2 PF07646.15 ORZ03092.1 - 8e-12 44.6 13.9 0.021 14.8 0.3 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 ORZ03092.1 - 7.1e-11 42.0 24.1 1.3e-05 25.2 0.3 6.5 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 ORZ03092.1 - 3.8e-10 39.6 26.4 1.7e-06 27.9 0.9 5.9 5 1 1 6 6 5 4 Galactose oxidase, central domain Kinase-like PF14531.6 ORZ03092.1 - 5.1e-06 26.0 0.0 7.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 ORZ03092.1 - 0.00036 19.9 0.0 0.0031 16.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Rick_17kDa_Anti PF05433.15 ORZ03092.1 - 0.00068 19.4 1.5 0.0019 18.0 1.5 1.7 1 0 0 1 1 1 1 Glycine zipper 2TM domain CD34_antigen PF06365.12 ORZ03092.1 - 0.0013 18.3 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Gly-zipper_Omp PF13488.6 ORZ03092.1 - 0.013 15.5 4.7 0.04 13.9 4.7 1.8 1 0 0 1 1 1 0 Glycine zipper PTP_tm PF18861.1 ORZ03092.1 - 0.016 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LapA_dom PF06305.11 ORZ03092.1 - 0.038 13.8 0.1 0.086 12.7 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 ORZ03092.1 - 0.065 12.7 0.8 0.2 11.1 0.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CcmD PF04995.14 ORZ03092.1 - 0.096 12.8 0.5 0.24 11.5 0.5 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Gly-zipper_YMGG PF13441.6 ORZ03092.1 - 0.2 11.4 5.0 0.46 10.3 5.0 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Sgf11 PF08209.11 ORZ03093.1 - 1.2e-13 50.4 0.3 1.2e-13 50.4 0.3 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) APG17 PF04108.12 ORZ03093.1 - 0.0066 15.6 1.0 0.0081 15.3 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Sec5 PF15469.6 ORZ03093.1 - 0.031 14.1 3.2 0.047 13.5 3.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF2321 PF10083.9 ORZ03093.1 - 0.84 9.3 5.3 0.42 10.2 1.5 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) UCH PF00443.29 ORZ03095.1 - 1.2e-14 54.4 0.0 1.1e-13 51.3 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORZ03095.1 - 0.00017 21.3 0.1 0.024 14.2 0.0 2.9 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L34e PF01199.18 ORZ03095.1 - 0.03 14.6 1.0 0.088 13.1 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L34e UBA_4 PF14555.6 ORZ03095.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain D_CNTX PF17492.2 ORZ03095.1 - 0.2 11.8 3.7 4 7.7 1.0 2.6 2 0 0 2 2 2 0 Delta Ctenitoxins COX16 PF14138.6 ORZ03095.1 - 0.47 11.0 2.0 1.6 9.3 2.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 3HCDH_N PF02737.18 ORZ03096.1 - 1e-57 195.0 2.4 1.8e-57 194.1 2.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORZ03096.1 - 1.4e-32 112.1 0.1 4.2e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORZ03096.1 - 1.2e-05 25.5 4.3 0.0002 21.6 4.3 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 ORZ03096.1 - 5.1e-05 22.7 0.1 7.3e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORZ03096.1 - 0.0048 17.4 0.3 0.016 15.8 0.1 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 ORZ03096.1 - 0.0048 17.2 1.5 0.0097 16.2 1.5 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ORZ03096.1 - 0.0071 15.7 4.3 0.012 14.9 3.2 1.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ORZ03096.1 - 0.008 16.4 0.3 0.018 15.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ORZ03096.1 - 0.012 15.3 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 ORZ03096.1 - 0.012 16.1 0.8 0.02 15.4 0.8 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 ORZ03096.1 - 0.017 15.7 2.3 0.066 13.8 2.3 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 ORZ03096.1 - 0.021 15.3 1.0 0.04 14.4 1.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ORZ03096.1 - 0.024 14.2 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORZ03096.1 - 0.027 14.5 0.6 0.049 13.6 0.6 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 ORZ03096.1 - 0.031 13.6 0.4 0.054 12.9 0.3 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 ORZ03096.1 - 0.037 13.6 0.2 0.055 13.0 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ORZ03096.1 - 0.06 12.4 1.7 0.15 11.1 1.6 1.6 1 1 1 2 2 2 0 Glucose inhibited division protein A Epimerase PF01370.21 ORZ03096.1 - 0.067 12.6 0.2 0.088 12.2 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PglD_N PF17836.1 ORZ03096.1 - 0.18 12.5 2.2 0.45 11.2 0.8 2.1 1 1 1 2 2 2 0 PglD N-terminal domain NAD_binding_4 PF07993.12 ORZ03097.1 - 1.2e-44 152.4 0.0 6.5e-44 150.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 ORZ03097.1 - 3.2e-08 33.3 0.0 1.2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase Epimerase PF01370.21 ORZ03097.1 - 6.1e-06 25.9 0.4 3.1e-05 23.5 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORZ03097.1 - 2.6e-05 23.4 0.0 0.088 11.8 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORZ03097.1 - 0.0045 16.2 0.0 0.75 8.9 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORZ03097.1 - 0.017 14.5 0.2 1 8.7 0.0 2.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase SUIM_assoc PF16619.5 ORZ03097.1 - 0.11 12.5 0.1 0.11 12.5 0.1 4.3 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Sterile PF03015.19 ORZ03097.1 - 0.12 12.6 0.0 0.42 10.9 0.0 2.0 1 0 0 1 1 1 0 Male sterility protein PH_9 PF15410.6 ORZ03100.1 - 1.9e-16 60.5 0.2 5.3e-16 59.0 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 ORZ03100.1 - 4.4e-14 52.6 0.1 7.8e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 ORZ03100.1 - 8e-07 29.5 0.0 4.4e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 PH domain TilS PF09179.11 ORZ03100.1 - 0.063 13.8 1.0 0.5 10.9 0.3 2.7 3 0 0 3 3 3 0 TilS substrate binding domain BTD PF09270.10 ORZ03101.1 - 6.1e-21 75.2 0.1 1.6e-19 70.7 0.1 2.6 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 ORZ03101.1 - 2.5e-20 73.7 12.2 4.7e-12 46.8 0.2 3.6 4 1 1 5 5 5 2 LAG1, DNA binding PIG-U PF06728.13 ORZ03101.1 - 0.23 10.5 0.6 8.7 5.3 0.1 2.4 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U Exo_endo_phos PF03372.23 ORZ03104.1 - 1.2e-05 25.0 0.1 2e-05 24.3 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ORZ03104.1 - 0.00013 21.8 0.1 0.00034 20.4 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DNA_gyraseB_C PF00986.21 ORZ03104.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Asn_synthase PF00733.21 ORZ03106.1 - 8.1e-95 318.5 1.4 1.2e-58 199.5 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORZ03106.1 - 2.9e-42 143.5 0.0 4.8e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORZ03106.1 - 2.6e-34 118.3 0.0 6.3e-34 117.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORZ03106.1 - 3.1e-08 33.4 0.0 6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ORZ03106.1 - 0.014 14.5 0.0 0.037 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 ORZ03106.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORZ03106.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase BAR PF03114.18 ORZ03107.1 - 1.5e-23 83.7 5.3 1.5e-23 83.7 5.3 1.4 1 1 0 1 1 1 1 BAR domain Seryl_tRNA_N PF02403.22 ORZ03107.1 - 0.012 15.9 1.3 0.76 10.0 0.9 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PIN_8 PF18476.1 ORZ03107.1 - 0.2 11.5 3.1 1.1 9.1 3.1 2.1 1 1 0 1 1 1 0 PIN like domain PolyA_pol_arg_C PF12626.7 ORZ03107.1 - 0.38 10.8 3.0 0.58 10.2 1.7 2.0 1 1 1 2 2 2 0 Polymerase A arginine-rich C-terminus DUF5344 PF17279.2 ORZ03107.1 - 2.2 8.9 10.6 0.36 11.4 1.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF948 PF06103.11 ORZ03107.1 - 2.5 8.4 5.0 21 5.5 0.0 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 ORZ03107.1 - 2.8 8.6 6.8 4.3 8.0 1.2 2.7 3 0 0 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 ORZ03107.1 - 9.2 6.3 8.0 4.8 7.2 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) GpcrRhopsn4 PF10192.9 ORZ03108.1 - 0.033 13.6 3.4 0.051 13.0 3.4 1.2 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain zf-rbx1 PF12678.7 ORZ03109.1 - 1.9e-08 34.5 6.0 2.2e-08 34.2 6.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORZ03109.1 - 3.7e-08 33.6 5.2 4.4e-08 33.3 5.2 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORZ03109.1 - 2.9e-07 30.2 4.3 3.4e-07 30.0 4.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORZ03109.1 - 0.00015 21.8 1.6 0.00018 21.5 1.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 ORZ03109.1 - 0.00016 21.4 4.1 0.00021 21.1 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORZ03109.1 - 0.00033 20.6 2.4 0.0085 16.1 1.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORZ03109.1 - 0.00045 20.1 1.9 0.00055 19.8 1.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORZ03109.1 - 0.00054 19.8 1.7 0.00065 19.5 1.7 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORZ03109.1 - 0.0025 17.6 1.8 0.0034 17.2 1.8 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORZ03109.1 - 0.0029 17.4 1.7 0.0034 17.2 1.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORZ03109.1 - 0.0043 17.1 1.7 0.0049 17.0 1.7 1.1 1 0 0 1 1 1 1 zinc RING finger of MSL2 FANCL_C PF11793.8 ORZ03109.1 - 0.012 15.8 2.1 0.012 15.8 2.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 ORZ03109.1 - 0.013 15.6 8.4 0.028 14.4 8.4 1.6 1 1 0 1 1 1 0 Zinc-finger zinc_ribbon_16 PF17034.5 ORZ03109.1 - 0.014 15.6 1.5 0.016 15.4 1.5 1.1 1 0 0 1 1 1 0 Zinc-ribbon like family Rad50_zn_hook PF04423.14 ORZ03109.1 - 0.024 14.5 0.2 0.038 13.8 0.2 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 ORZ03109.1 - 0.025 14.3 3.6 0.025 14.3 3.6 1.6 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 ORZ03109.1 - 0.049 13.2 6.3 0.094 12.4 6.5 1.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORZ03109.1 - 0.46 10.7 4.6 0.65 10.2 4.6 1.3 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 ORZ03109.1 - 0.64 9.9 2.8 2.5 8.0 3.5 1.5 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.25 ORZ03110.1 - 6.3e-62 209.3 0.0 8e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03110.1 - 9.7e-32 110.3 0.0 1.5e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03110.1 - 5.8e-07 29.1 0.0 1.3e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORZ03110.1 - 2.5e-05 23.4 0.3 3.9e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORZ03110.1 - 0.00034 20.2 0.1 0.00065 19.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORZ03110.1 - 0.0091 15.4 0.2 0.015 14.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 ORZ03110.1 - 0.12 12.0 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 ORZ03110.1 - 0.14 12.1 0.2 0.31 10.9 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family PrgI PF12666.7 ORZ03111.1 - 1.2 9.9 4.0 0.73 10.6 0.2 2.3 3 0 0 3 3 3 0 PrgI family protein DUF4059 PF13268.6 ORZ03111.1 - 1.5 9.3 7.4 0.13 12.7 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) DUF3290 PF11694.8 ORZ03111.1 - 1.9 8.4 4.8 0.71 9.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Homeodomain PF00046.29 ORZ03112.1 - 1.5e-20 72.8 1.7 2e-20 72.4 1.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORZ03112.1 - 0.00054 19.8 1.0 0.00086 19.2 0.1 1.7 2 0 0 2 2 2 1 Homeobox KN domain GH-E PF14410.6 ORZ03112.1 - 0.046 14.1 0.4 3.4 8.1 0.0 2.2 1 1 1 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues HTH_48 PF17906.1 ORZ03112.1 - 0.15 12.2 0.9 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Pkinase PF00069.25 ORZ03113.1 - 3.2e-71 239.8 0.0 4.6e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03113.1 - 2e-29 102.7 0.1 6.9e-20 71.4 0.1 2.3 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03113.1 - 1.3e-05 24.6 0.0 0.8 9.0 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 ORZ03113.1 - 0.014 14.8 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORZ03113.1 - 0.03 13.1 0.1 0.072 11.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 ORZ03113.1 - 0.099 12.6 0.1 2.7 7.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.19 ORZ03114.1 - 1.9e-116 389.0 0.0 1.6e-115 386.0 0.0 1.9 1 1 0 1 1 1 1 Actin cobW PF02492.19 ORZ03115.1 - 2.7e-50 170.4 0.3 4.2e-50 169.8 0.3 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORZ03115.1 - 3.9e-08 33.1 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ORZ03115.1 - 0.00078 19.4 0.9 0.69 9.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 ORZ03115.1 - 0.0033 16.5 0.8 0.0078 15.3 0.1 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORZ03115.1 - 0.0072 16.6 0.0 0.027 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORZ03115.1 - 0.0087 16.0 0.8 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 ORZ03115.1 - 0.015 14.9 1.4 1.5 8.3 0.3 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORZ03115.1 - 0.017 15.5 0.1 0.053 13.9 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain UvrD_C PF13361.6 ORZ03115.1 - 0.034 13.5 1.1 0.047 13.1 0.3 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.6 ORZ03115.1 - 0.035 14.7 0.8 0.13 12.8 0.8 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORZ03115.1 - 0.035 13.8 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 ORZ03115.1 - 0.036 14.1 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORZ03115.1 - 0.053 13.6 0.1 0.22 11.6 0.0 2.1 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORZ03115.1 - 0.088 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ORZ03115.1 - 0.088 13.3 0.5 0.24 11.9 0.3 2.0 1 1 0 1 1 1 0 ABC transporter p450 PF00067.22 ORZ03117.1 - 3.4e-44 151.4 0.0 3.1e-32 111.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3996 PF13161.6 ORZ03117.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) UQ_con PF00179.26 ORZ03118.1 - 9.5e-52 174.4 0.0 1.1e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORZ03118.1 - 0.00057 19.6 0.0 0.00074 19.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORZ03118.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.3 1 1 0 1 1 1 0 RWD domain GDI PF00996.18 ORZ03120.1 - 5.5e-226 750.1 0.0 6.3e-226 749.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Cbl_N3 PF02762.14 ORZ03120.1 - 0.11 12.4 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Mito_carr PF00153.27 ORZ03121.1 - 4.8e-22 77.7 0.8 1.6e-15 56.8 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein Med3 PF11593.8 ORZ03121.1 - 0.16 11.1 4.1 0.22 10.7 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ETC_C1_NDUFA4 PF04800.12 ORZ03124.1 - 1e-34 118.6 0.9 1.5e-34 118.1 0.9 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region Lon_C PF05362.13 ORZ03125.1 - 3.8e-76 255.2 0.3 7.2e-76 254.3 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORZ03125.1 - 2.4e-27 96.2 0.9 2.4e-27 96.2 0.9 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORZ03125.1 - 2.9e-21 76.3 0.0 1.6e-20 73.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORZ03125.1 - 1.5e-06 28.3 0.0 1.4e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORZ03125.1 - 3.3e-06 26.9 0.0 7.9e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 ORZ03125.1 - 8.2e-05 21.7 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 ORZ03125.1 - 0.00021 21.5 0.0 0.011 16.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORZ03125.1 - 0.00024 21.5 1.0 0.0013 19.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 ORZ03125.1 - 0.00034 20.5 0.0 0.0008 19.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORZ03125.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORZ03125.1 - 0.0044 17.6 0.1 0.026 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORZ03125.1 - 0.0049 17.4 1.5 0.93 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORZ03125.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 ORZ03125.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 ORZ03125.1 - 0.025 14.5 0.6 0.52 10.2 0.0 3.2 4 0 0 4 4 4 0 NACHT domain AAA_2 PF07724.14 ORZ03125.1 - 0.025 14.7 0.0 0.083 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 ORZ03125.1 - 0.057 13.8 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 ORZ03125.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORZ03125.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORZ03125.1 - 0.11 12.5 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 ORZ03125.1 - 0.21 11.1 0.3 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Occludin_ELL PF07303.13 ORZ03125.1 - 1.1 10.0 3.4 9.1 7.1 0.4 2.7 2 0 0 2 2 2 0 Occludin homology domain HK PF02110.15 ORZ03126.1 - 3.6e-76 255.8 3.6 7.8e-76 254.7 3.6 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 ORZ03126.1 - 7.9e-62 207.8 2.0 1.5e-61 206.9 0.5 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 ORZ03126.1 - 2.3e-08 33.8 1.9 4.2e-08 33.0 1.9 1.4 1 0 0 1 1 1 1 Carbohydrate kinase QRPTase_C PF01729.19 ORZ03126.1 - 0.068 12.9 0.0 0.48 10.2 0.0 2.3 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Zn_clus PF00172.18 ORZ03127.1 - 3.9e-11 42.9 21.5 2.5e-06 27.5 7.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_63 PF03200.16 ORZ03127.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain adh_short PF00106.25 ORZ03128.1 - 2.3e-45 154.5 5.6 2.7e-45 154.2 5.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORZ03128.1 - 9.6e-41 139.9 4.9 1.2e-40 139.5 4.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORZ03128.1 - 1.5e-08 34.8 5.1 7.7e-08 32.4 5.1 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ORZ03128.1 - 0.00036 19.6 0.3 0.0012 17.9 0.1 1.9 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 ORZ03128.1 - 0.034 14.7 0.4 0.091 13.3 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ORZ03128.1 - 0.035 13.6 0.4 0.052 13.0 0.4 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORZ03128.1 - 0.049 13.9 0.9 0.11 12.7 0.8 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORZ03128.1 - 0.071 13.4 0.3 0.17 12.2 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain MlrC_C PF07171.12 ORZ03128.1 - 0.8 9.9 5.0 0.36 11.0 1.6 1.9 2 0 0 2 2 2 0 MlrC C-terminus Y_phosphatase3 PF13350.6 ORZ03129.1 - 9.9e-32 110.8 0.0 1.1e-31 110.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ORZ03129.1 - 2.7e-08 33.6 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORZ03129.1 - 0.002 17.7 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 ORZ03129.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 ORZ03129.1 - 0.055 13.3 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Fungal_trans PF04082.18 ORZ03130.1 - 2.9e-18 65.8 0.8 2.9e-18 65.8 0.8 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORZ03130.1 - 9.8e-07 28.8 9.8 1.8e-06 27.9 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribul_P_3_epim PF00834.19 ORZ03131.1 - 3.1e-44 150.7 0.1 4e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 ORZ03131.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 ORZ03131.1 - 0.017 14.7 0.2 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family O-FucT PF10250.9 ORZ03133.1 - 0.00039 20.2 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase GspL_C PF12693.7 ORZ03133.1 - 1.5 8.6 4.4 20 5.0 2.8 2.2 2 0 0 2 2 2 0 GspL periplasmic domain MFS_1 PF07690.16 ORZ03134.1 - 5.2e-21 75.0 37.3 5.2e-21 75.0 37.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ03134.1 - 6e-06 25.4 24.8 9.2e-05 21.5 24.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter SecY PF00344.20 ORZ03135.1 - 1.6e-68 231.2 10.1 2.2e-68 230.8 10.1 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORZ03135.1 - 8.3e-18 63.9 0.5 2.1e-17 62.6 0.5 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p QCR10 PF09796.9 ORZ03135.1 - 0.0056 16.7 4.3 0.07 13.2 0.1 3.5 4 0 0 4 4 4 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pho88 PF10032.9 ORZ03136.1 - 1.2e-50 171.3 0.0 1.5e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF3817 PF12823.7 ORZ03136.1 - 0.092 13.6 1.2 16 6.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) Ribosomal_S30 PF04758.14 ORZ03137.1 - 1.9e-28 98.4 10.7 2.3e-28 98.1 10.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_L1 PF00687.21 ORZ03138.1 - 8.8e-35 120.3 0.3 1.2e-34 119.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Imm40 PF15569.6 ORZ03138.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 40 Alk_phosphatase PF00245.20 ORZ03139.1 - 4.5e-98 328.9 0.0 7.8e-98 328.1 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORZ03139.1 - 4.8e-05 22.8 0.1 0.00017 21.1 0.1 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Ras PF00071.22 ORZ03140.1 - 6.2e-58 195.0 0.3 7.3e-58 194.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ03140.1 - 1e-32 112.9 0.1 1.7e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ03140.1 - 1.7e-13 50.4 0.0 1.9e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORZ03140.1 - 9.1e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORZ03140.1 - 8.1e-07 28.6 0.1 1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORZ03140.1 - 1.1e-05 25.1 0.1 0.00032 20.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORZ03140.1 - 9.1e-05 22.4 0.2 0.0033 17.4 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase cobW PF02492.19 ORZ03140.1 - 0.0022 17.6 0.0 0.0053 16.4 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ORZ03140.1 - 0.0056 17.1 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 ORZ03140.1 - 0.0064 16.2 0.3 0.11 12.2 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 ORZ03140.1 - 0.0099 15.3 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 ORZ03140.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 ORZ03140.1 - 0.013 14.7 0.9 0.028 13.7 0.1 1.9 3 0 0 3 3 3 0 Septin AAA_22 PF13401.6 ORZ03140.1 - 0.014 15.6 0.0 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORZ03140.1 - 0.016 14.9 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORZ03140.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 ORZ03140.1 - 0.046 13.6 0.4 0.092 12.7 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ORZ03140.1 - 0.066 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 ORZ03140.1 - 0.075 13.0 0.0 0.3 11.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 ORZ03140.1 - 0.087 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 ORZ03140.1 - 0.088 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.32 ORZ03141.1 - 2.2e-07 31.4 2.6 1.1 10.3 0.1 6.3 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03141.1 - 0.0041 17.4 0.2 1.4 9.3 0.0 3.2 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORZ03141.1 - 0.057 13.5 0.0 32 4.6 0.0 3.6 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region ID PF18543.1 ORZ03141.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Intracellular delivery domain U3_snoRNA_assoc PF08297.11 ORZ03142.1 - 1.5e-05 25.6 1.3 1.5e-05 25.6 1.3 3.7 2 1 0 2 2 2 1 U3 snoRNA associated CDC27 PF09507.10 ORZ03142.1 - 9.5 5.5 38.6 18 4.6 38.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DHHC PF01529.20 ORZ03143.1 - 3.3e-36 124.3 10.6 3.3e-36 124.3 10.6 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF680 PF05079.12 ORZ03143.1 - 0.13 12.9 0.5 0.34 11.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF680) FliN_N PF16973.5 ORZ03143.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal APS_kinase PF01583.20 ORZ03144.1 - 5.2e-72 240.9 0.0 6.2e-72 240.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ORZ03144.1 - 7.3e-09 35.9 0.0 1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORZ03144.1 - 0.00051 20.6 0.0 0.0021 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORZ03144.1 - 0.0052 16.3 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 ORZ03144.1 - 0.015 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain LisH PF08513.11 ORZ03144.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 LisH AAA_16 PF13191.6 ORZ03144.1 - 0.057 13.8 0.1 0.08 13.3 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 ORZ03144.1 - 0.069 13.0 0.2 0.77 9.6 0.1 2.2 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 ORZ03144.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF463 PF04317.12 ORZ03144.1 - 0.14 11.1 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 PH PF00169.29 ORZ03145.1 - 0.016 15.7 0.0 0.05 14.1 0.0 1.9 1 0 0 1 1 1 0 PH domain Glyco_hydro_16 PF00722.21 ORZ03146.1 - 7.8e-37 126.4 1.1 9.7e-37 126.1 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HhH-GPD PF00730.25 ORZ03147.1 - 1.5e-18 67.2 0.0 4.4e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 ORZ03147.1 - 4.5e-17 62.0 0.0 9.4e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 ORZ03147.1 - 1.3e-05 24.8 0.0 3.8e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ORZ03147.1 - 0.00034 20.9 10.5 0.0017 18.7 5.2 2.5 2 0 0 2 2 2 2 Iron-sulfur binding domain of endonuclease III PPR_2 PF13041.6 ORZ03148.1 - 2.9e-41 139.4 3.2 8.5e-11 41.9 0.0 7.7 5 2 2 7 7 7 6 PPR repeat family PPR PF01535.20 ORZ03148.1 - 2e-29 99.8 0.9 1.1e-07 31.6 0.0 8.9 8 1 0 8 8 8 5 PPR repeat PPR_3 PF13812.6 ORZ03148.1 - 2.3e-26 91.6 1.7 3.1e-09 36.8 0.0 7.2 4 3 4 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORZ03148.1 - 6.8e-22 76.9 0.0 5e-05 22.9 0.0 6.7 6 0 0 6 6 6 4 PPR repeat PPR_long PF17177.4 ORZ03148.1 - 5.3e-18 65.2 4.5 6.5e-05 22.4 0.0 5.0 3 2 2 5 5 5 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORZ03148.1 - 7.2e-08 32.6 3.0 0.07 14.0 0.1 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ03148.1 - 0.00058 20.3 0.3 0.12 12.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORZ03148.1 - 0.00099 19.5 2.0 0.036 14.7 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ03148.1 - 0.0023 17.9 2.3 6.4 7.2 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORZ03148.1 - 0.0043 16.9 0.2 0.52 10.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ03148.1 - 0.0051 16.6 0.0 4.1 7.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ03148.1 - 0.0052 17.0 0.1 0.25 11.7 0.0 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat ATP13 PF12921.7 ORZ03148.1 - 0.018 14.9 0.0 0.37 10.7 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ATPase expression TPR_8 PF13181.6 ORZ03148.1 - 0.022 15.0 0.0 55 4.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ERAP1_C PF11838.8 ORZ03148.1 - 0.022 14.3 0.5 0.15 11.6 0.1 2.3 1 1 0 2 2 2 0 ERAP1-like C-terminal domain TPR_7 PF13176.6 ORZ03148.1 - 0.03 14.3 0.1 2.8 8.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ03148.1 - 0.091 13.4 4.8 54 4.7 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Clathrin PF00637.20 ORZ03148.1 - 0.93 9.4 2.9 7.3 6.5 0.0 3.2 3 0 0 3 3 3 0 Region in Clathrin and VPS RPM2 PF08579.11 ORZ03148.1 - 1.6 9.2 4.3 80 3.7 0.0 4.1 4 2 1 5 5 5 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_16 PF13432.6 ORZ03148.1 - 3.9 8.2 10.0 20 5.9 0.3 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 ORZ03149.1 - 1.8e-50 171.9 21.7 1.7e-48 165.4 21.7 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family PUF PF00806.19 ORZ03150.1 - 1.7e-71 232.1 18.0 9.7e-10 37.6 0.2 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 ORZ03150.1 - 0.00061 20.1 5.1 6.1 7.2 0.0 4.7 1 1 3 4 4 4 2 CPL (NUC119) domain sCache_2 PF17200.4 ORZ03150.1 - 0.02 14.8 1.4 45 3.9 0.0 4.5 5 0 0 5 5 5 0 Single Cache domain 2 NABP PF07990.12 ORZ03150.1 - 0.13 11.8 0.2 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Nucleic acid binding protein NABP Pribosyltran PF00156.27 ORZ03151.1 - 2.8e-16 59.5 0.0 3.9e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORZ03151.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DSPc PF00782.20 ORZ03153.1 - 1.9e-23 82.7 0.0 4.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 ORZ03153.1 - 7.5e-09 36.1 0.1 3.2e-05 24.4 0.0 3.7 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 ORZ03153.1 - 0.0061 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 ORZ03153.1 - 0.057 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain Formyl_trans_N PF00551.19 ORZ03154.1 - 4.1e-50 170.0 0.1 5.7e-50 169.6 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase Aldose_epim PF01263.20 ORZ03155.1 - 1.5e-75 254.3 0.4 1.7e-75 254.1 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1344 PF07076.11 ORZ03155.1 - 0.078 12.9 0.5 14 5.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) BRE1 PF08647.11 ORZ03156.1 - 7.3e-08 32.4 1.0 7.3e-08 32.4 1.0 7.0 7 2 0 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 ORZ03156.1 - 1.4e-07 31.2 9.0 2.7e-07 30.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ03156.1 - 1.5e-05 24.7 10.5 1.5e-05 24.7 10.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORZ03156.1 - 2.9e-05 23.8 9.7 2.9e-05 23.8 9.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORZ03156.1 - 4.8e-05 23.2 9.9 0.00011 22.1 9.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORZ03156.1 - 0.00017 21.9 10.0 0.00026 21.2 9.1 1.8 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 ORZ03156.1 - 0.0004 20.2 6.9 0.00078 19.3 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORZ03156.1 - 0.0015 18.7 4.5 0.0015 18.7 4.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORZ03156.1 - 0.013 15.5 8.1 0.037 14.1 8.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 ORZ03156.1 - 0.035 14.0 2.5 0.097 12.6 2.5 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORZ03156.1 - 0.13 12.1 3.5 0.3 10.9 3.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Toxin-deaminase PF14424.6 ORZ03156.1 - 0.21 11.7 2.1 0.46 10.6 0.3 2.4 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases DZR PF12773.7 ORZ03156.1 - 1.3 9.1 5.1 3.3 7.8 5.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon ECM11 PF15463.6 ORZ03156.1 - 1.6 9.3 18.3 3.3 8.3 3.5 4.5 3 1 1 4 4 4 0 Extracellular mutant protein 11 zf-C3HC4_4 PF15227.6 ORZ03156.1 - 2 8.7 12.0 0.18 12.0 7.3 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING NmrA PF05368.13 ORZ03157.1 - 5.7e-16 58.8 0.2 3.8e-15 56.1 0.2 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORZ03157.1 - 1.5e-14 54.3 0.1 2e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORZ03157.1 - 0.0014 17.7 0.1 0.0093 15.0 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORZ03157.1 - 0.0025 17.3 0.1 0.0054 16.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ORZ03157.1 - 0.012 15.9 0.1 0.036 14.3 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain Adeno_Penton_B PF01686.17 ORZ03157.1 - 0.035 12.6 0.0 0.052 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus penton base protein NAD_binding_4 PF07993.12 ORZ03157.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 ORZ03157.1 - 0.11 12.5 0.2 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 ORZ03158.1 - 1.2e-41 142.2 0.0 2.9e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ03158.1 - 8e-09 35.2 0.1 2e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORZ03158.1 - 1.8e-05 24.7 0.1 9e-05 22.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORZ03158.1 - 7.5e-05 23.0 0.0 0.0053 17.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORZ03158.1 - 9.5e-05 22.8 0.1 0.0016 18.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 ORZ03158.1 - 0.00013 22.1 0.1 0.00082 19.5 0.0 2.3 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORZ03158.1 - 0.00054 19.2 0.0 0.00099 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORZ03158.1 - 0.0022 17.7 0.0 0.0064 16.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ORZ03158.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORZ03158.1 - 0.012 15.3 0.1 0.12 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORZ03158.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORZ03158.1 - 0.021 15.0 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORZ03158.1 - 0.033 14.6 0.0 0.096 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 ORZ03158.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ORZ03158.1 - 0.035 14.0 0.5 6.6 6.6 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 ORZ03158.1 - 0.035 14.7 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 ORZ03158.1 - 0.043 13.0 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 ORZ03158.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 ORZ03158.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORZ03158.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 ORZ03158.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORZ03158.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RhoGEF PF00621.20 ORZ03159.1 - 4.1e-37 128.2 0.4 7.7e-37 127.3 0.4 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORZ03159.1 - 1.4e-12 47.9 1.2 2.8e-12 46.9 1.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORZ03159.1 - 5.1e-09 36.1 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TFIIA PF03153.13 ORZ03160.1 - 0.0038 17.3 10.7 0.0057 16.7 10.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 ORZ03160.1 - 0.21 10.8 4.8 0.32 10.3 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 ORZ03160.1 - 0.58 8.9 6.9 0.71 8.7 6.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.12 ORZ03160.1 - 1.1 8.9 10.6 2.1 8.0 10.7 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDP-OH_P_transf PF01066.21 ORZ03161.1 - 5.5e-19 68.7 0.3 5.5e-19 68.7 0.3 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Aminotran_5 PF00266.19 ORZ03162.1 - 4.1e-27 95.1 0.0 5.2e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORZ03162.1 - 0.0026 17.0 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Sel1 PF08238.12 ORZ03163.1 - 1.7e-45 152.4 17.7 1.5e-09 38.2 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_8 PF13181.6 ORZ03163.1 - 0.26 11.6 4.0 19 5.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat WH1 PF00568.23 ORZ03164.1 - 4e-23 81.5 0.0 6.1e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 ORZ03164.1 - 0.00067 20.0 0.2 0.0019 18.5 0.2 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 ORZ03164.1 - 0.28 11.1 3.0 0.6 10.0 0.2 2.6 3 0 0 3 3 3 0 WH2 motif PH_TFIIH PF08567.11 ORZ03165.1 - 3.2e-21 75.4 0.1 7.6e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 ORZ03165.1 - 3.3e-16 59.0 1.0 1.7e-11 43.9 0.1 2.8 2 0 0 2 2 2 2 BSD domain DUF677 PF05055.12 ORZ03165.1 - 0.0038 16.2 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF677) HSF_DNA-bind PF00447.17 ORZ03166.1 - 3.3e-32 111.0 1.0 3.3e-32 111.0 1.0 2.0 3 0 0 3 3 3 1 HSF-type DNA-binding SNAP PF14938.6 ORZ03166.1 - 0.072 12.5 0.3 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Cdc6_C PF09079.11 ORZ03166.1 - 0.15 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Suf PF05843.14 ORZ03166.1 - 2.1 8.2 14.6 3.5 7.5 14.6 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HAGH_C PF16123.5 ORZ03167.1 - 2.9e-24 85.4 0.3 4.1e-24 84.9 0.3 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORZ03167.1 - 1.6e-11 44.6 3.4 6e-10 39.5 3.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORZ03167.1 - 0.0017 17.9 0.1 0.0038 16.8 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORZ03167.1 - 0.036 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Aldedh PF00171.22 ORZ03168.1 - 1.1e-81 274.7 0.0 1.3e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Far-17a_AIG1 PF04750.14 ORZ03169.1 - 3.6e-34 117.9 11.1 4.2e-34 117.7 11.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Zn_clus PF00172.18 ORZ03170.1 - 5.9e-11 42.3 23.4 1.4e-06 28.3 9.3 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Importin_rep_4 PF18808.1 ORZ03171.1 - 1.3e-30 105.5 0.6 1.3e-30 105.5 0.6 3.7 3 1 0 3 3 3 1 Importin repeat HEAT_2 PF13646.6 ORZ03171.1 - 5.7e-21 74.7 10.2 4.2e-09 36.7 0.0 8.4 6 2 3 9 9 8 4 HEAT repeats HEAT PF02985.22 ORZ03171.1 - 9.3e-21 72.1 10.7 0.0006 19.8 0.0 11.7 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.6 ORZ03171.1 - 9.7e-16 57.9 11.4 5.4e-07 30.0 0.0 9.7 10 3 2 12 12 12 2 HEAT-like repeat Importin_rep_6 PF18829.1 ORZ03171.1 - 1.4e-15 57.3 2.5 6.8e-15 55.1 0.1 3.1 3 0 0 3 3 3 1 Importin repeat 6 DUF3385 PF11865.8 ORZ03171.1 - 3.2e-11 43.4 0.8 0.0036 17.2 0.0 7.4 6 2 1 8 8 8 3 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 ORZ03171.1 - 4e-11 43.4 0.0 0.028 15.0 0.0 7.0 4 4 3 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORZ03171.1 - 8.3e-07 29.2 0.7 0.31 11.1 0.0 5.4 3 3 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORZ03171.1 - 2.4e-06 26.4 1.1 0.017 13.7 0.1 3.6 3 0 0 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.8 ORZ03171.1 - 0.00021 20.6 2.7 0.74 8.9 0.1 5.1 6 1 0 6 6 6 1 RNAPII transcription regulator C-terminal Importin_rep_5 PF18816.1 ORZ03171.1 - 0.00027 21.2 0.2 0.0011 19.2 0.2 2.2 1 0 0 1 1 1 1 Importin repeat UNC45-central PF11701.8 ORZ03171.1 - 0.00028 20.9 1.0 9.5 6.2 0.0 4.7 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central RIX1 PF08167.12 ORZ03171.1 - 0.0013 18.5 0.0 3.4 7.4 0.0 4.4 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 ORZ03171.1 - 0.0046 17.1 0.5 1.9 8.7 0.1 4.4 4 2 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 ORZ03171.1 - 0.0046 16.9 0.6 4.5 7.5 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 ORZ03171.1 - 0.0056 16.3 0.0 4.8 6.7 0.0 4.4 4 1 1 5 5 5 1 CLASP N terminal V-ATPase_H_N PF03224.14 ORZ03171.1 - 0.061 12.6 0.4 0.3 10.4 0.0 2.3 2 1 1 3 3 3 0 V-ATPase subunit H Tti2 PF10521.9 ORZ03171.1 - 0.064 12.8 0.0 1.4 8.4 0.0 3.1 1 1 0 1 1 1 0 Tti2 family DUF668 PF05003.12 ORZ03171.1 - 0.12 12.9 0.6 27 5.3 0.1 4.0 4 0 0 4 4 3 0 Protein of unknown function (DUF668) CTK3_C PF12350.8 ORZ03171.1 - 8.6 6.6 6.0 1.4 9.1 0.7 2.2 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus KxDL PF10241.9 ORZ03172.1 - 0.019 15.2 3.1 0.07 13.4 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein Phage_Mu_Gam PF07352.12 ORZ03172.1 - 0.022 14.7 0.6 0.022 14.7 0.6 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Herpes_ICP4_N PF03584.15 ORZ03172.1 - 0.04 13.8 0.4 0.078 12.8 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region NPV_P10 PF05531.12 ORZ03172.1 - 0.082 13.4 0.1 0.76 10.3 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1S3 PF15753.5 ORZ03172.1 - 2.3 8.3 5.9 9 6.4 0.3 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 FliD_N PF02465.18 ORZ03172.1 - 2.5 8.8 4.3 2.4 8.9 1.3 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SBDS PF01172.18 ORZ03173.1 - 5.8e-14 51.9 0.0 6.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S8 PF00082.22 ORZ03174.1 - 4.1e-40 137.9 1.2 4.1e-40 137.9 1.2 2.3 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 ORZ03174.1 - 3.2e-26 91.2 1.0 8.6e-26 89.8 1.0 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 ORZ03174.1 - 0.0075 16.8 0.4 0.055 14.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal of Subtilase family S8_pro-domain PF16470.5 ORZ03174.1 - 0.029 15.1 3.5 0.16 12.8 3.5 2.3 1 1 0 1 1 1 0 Peptidase S8 pro-domain SOG2 PF10428.9 ORZ03174.1 - 0.83 8.8 10.1 1.2 8.3 10.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein 2OG-FeII_Oxy_2 PF13532.6 ORZ03175.1 - 6.6e-15 55.8 0.4 4.4e-14 53.1 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.18 ORZ03176.1 - 8.7e-76 255.2 24.6 1e-75 255.0 24.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein STIMATE PF12400.8 ORZ03176.1 - 0.056 14.0 0.2 0.18 12.3 0.2 1.9 1 0 0 1 1 1 0 STIMATE family Herpes_US9 PF06072.11 ORZ03176.1 - 0.19 11.6 2.3 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 UBA2_C PF16195.5 ORZ03179.1 - 0.08 13.6 0.9 0.08 13.6 0.9 2.7 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Spt20 PF12090.8 ORZ03179.1 - 2.6 7.6 12.9 0.39 10.3 4.7 2.4 2 0 0 2 2 2 0 Spt20 family Malic_M PF03949.15 ORZ03180.1 - 8.8e-91 303.7 0.0 1.1e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORZ03180.1 - 6.2e-73 244.5 0.0 1.3e-72 243.5 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Anp1 PF03452.14 ORZ03181.1 - 1.9e-91 306.1 0.0 2.2e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 ORZ03181.1 - 8.9e-05 22.4 0.0 0.0036 17.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Methyltransf_25 PF13649.6 ORZ03182.1 - 1.8e-09 38.2 0.0 3.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ03182.1 - 1.9e-09 37.6 0.0 5.1e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03182.1 - 2.8e-09 37.5 0.0 6.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03182.1 - 0.0004 20.2 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ03182.1 - 0.0021 18.8 0.0 0.0062 17.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORZ03182.1 - 0.022 14.2 0.0 0.062 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase RTT107_BRCT_5 PF16770.5 ORZ03185.1 - 6.9e-10 38.7 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 ORZ03185.1 - 3.8e-06 27.2 0.0 1.1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORZ03185.1 - 6.7e-06 26.4 0.0 0.00025 21.4 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PAP2 PF01569.21 ORZ03188.1 - 2.8e-15 56.3 7.9 2.8e-15 56.3 7.9 1.5 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 ORZ03188.1 - 0.01 16.0 2.5 0.058 13.5 0.1 2.3 1 1 1 2 2 2 0 Divergent PAP2 family WD40 PF00400.32 ORZ03189.1 - 6.4e-14 52.1 8.1 9.1e-06 26.3 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 ORZ03189.1 - 5.3e-10 39.4 0.1 6.2e-09 36.0 0.0 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 ORZ03189.1 - 6.4e-07 29.6 2.8 0.0019 18.5 0.3 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ03189.1 - 0.00015 21.7 0.7 0.00036 20.5 0.8 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Vac14_Fig4_bd PF11916.8 ORZ03190.1 - 1.4e-81 272.5 6.4 1.4e-81 272.5 6.4 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 ORZ03190.1 - 7.4e-46 154.7 0.0 8.7e-40 135.2 0.0 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 ORZ03190.1 - 2.7e-13 48.9 2.3 0.014 15.6 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 ORZ03190.1 - 1.1e-09 38.6 1.3 0.028 14.9 0.1 5.8 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 ORZ03190.1 - 1.3e-07 31.4 0.1 1.9 8.6 0.0 5.8 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 ORZ03190.1 - 9.7e-06 25.3 0.2 0.31 10.5 0.0 4.7 5 1 0 5 5 5 2 CLASP N terminal MMS19_C PF12460.8 ORZ03190.1 - 2.8e-05 23.4 1.8 0.057 12.5 0.0 4.2 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 ORZ03190.1 - 3.6e-05 24.1 2.5 13 6.2 0.0 5.8 7 0 0 7 7 7 1 HEAT repeats Cnd1 PF12717.7 ORZ03190.1 - 0.00027 21.0 2.6 1.9 8.5 0.1 4.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 ORZ03190.1 - 0.013 15.1 0.1 5.1 6.5 0.0 3.4 3 1 0 3 3 3 0 Tti2 family Dopey_N PF04118.14 ORZ03190.1 - 0.021 14.0 0.5 5.5 6.0 0.0 3.4 3 0 0 3 3 3 0 Dopey, N-terminal RasGEF_N_2 PF14663.6 ORZ03190.1 - 0.067 13.6 6.3 5.5 7.4 0.1 4.5 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CCDC53 PF10152.9 ORZ03190.1 - 9.9 6.6 6.5 2 8.8 2.3 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Mog1 PF04603.12 ORZ03191.1 - 9.2e-39 133.0 2.1 1.2e-38 132.6 2.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF3375 PF11855.8 ORZ03191.1 - 0.014 14.4 2.2 0.016 14.2 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Tetraspanin PF00335.20 ORZ03192.1 - 1.1e-12 48.1 11.2 1.7e-12 47.6 11.2 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2721 PF11026.8 ORZ03192.1 - 2.3 8.1 12.4 9.6 6.1 2.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) RGS PF00615.19 ORZ03193.1 - 1.7e-09 38.0 0.0 1.1e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Synaptobrevin PF00957.21 ORZ03193.1 - 0.0032 17.2 1.0 0.0086 15.9 1.0 1.7 1 0 0 1 1 1 1 Synaptobrevin DUF2207 PF09972.9 ORZ03193.1 - 4.9 5.8 8.4 41 2.8 7.7 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Metallophos PF00149.28 ORZ03194.1 - 1.2e-11 45.5 0.4 1.9e-11 44.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORZ03194.1 - 4.4e-09 36.8 0.1 3.2e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORZ03194.1 - 0.0037 16.6 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily PC-Esterase PF13839.6 ORZ03195.1 - 3.4e-08 33.6 0.0 4e-06 26.8 0.1 2.7 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL_2 PF13472.6 ORZ03195.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ELO PF01151.18 ORZ03196.1 - 2.4e-57 194.3 28.9 2.9e-57 194.1 28.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RhoGAP PF00620.27 ORZ03197.1 - 2.8e-36 124.6 0.0 8.7e-36 123.0 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FTHFS PF01268.19 ORZ03198.1 - 1.6e-264 878.3 0.3 1.6e-264 878.3 0.3 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 ORZ03198.1 - 6.6e-68 227.0 1.1 1.6e-67 225.8 1.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ORZ03198.1 - 2.9e-40 137.1 1.0 6.5e-40 136.0 1.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 ORZ03198.1 - 0.012 14.5 0.3 0.023 13.7 0.3 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AdoHcyase_NAD PF00670.21 ORZ03198.1 - 0.04 14.0 0.4 1.3 9.1 0.4 2.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CbiA PF01656.23 ORZ03198.1 - 0.13 12.3 0.3 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTC1 PF15489.6 ORZ03199.1 - 5.8e-14 50.7 0.0 2.4e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 E1-E2_ATPase PF00122.20 ORZ03200.1 - 1.6e-45 154.8 1.1 1.6e-45 154.8 1.1 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORZ03200.1 - 1.1e-22 80.7 3.4 1.1e-22 80.7 3.4 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORZ03200.1 - 2.6e-17 62.7 0.0 4.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORZ03200.1 - 8.4e-16 58.9 0.8 7.9e-14 52.4 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ03200.1 - 3e-15 55.7 0.6 8.6e-14 51.0 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 ORZ03200.1 - 0.0023 18.4 0.0 0.011 16.2 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORZ03200.1 - 0.017 14.9 1.0 0.071 12.8 0.3 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Borrelia_P13 PF05628.12 ORZ03200.1 - 0.075 13.0 4.1 0.16 11.9 0.0 3.0 2 1 1 3 3 3 0 Borrelia membrane protein P13 S_4TM PF18159.1 ORZ03200.1 - 4.4 6.5 11.8 0.19 11.0 1.1 3.0 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain OrfB_Zn_ribbon PF07282.11 ORZ03201.1 - 0.003 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORZ03202.1 - 4.5e-05 23.3 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Serinc PF03348.15 ORZ03204.1 - 1.1e-158 528.7 10.5 1.3e-158 528.5 10.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Oxysterol_BP PF01237.18 ORZ03205.1 - 1.5e-115 386.0 1.7 1.5e-115 386.0 1.7 1.9 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 ORZ03205.1 - 1.2e-20 73.6 0.1 3.9e-20 71.9 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORZ03205.1 - 4.7e-11 43.1 0.4 2.8e-08 34.2 0.1 3.0 3 0 0 3 3 3 2 PH domain GOLD_2 PF13897.6 ORZ03205.1 - 8.6e-08 32.8 1.1 1.4e-05 25.6 0.1 3.4 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 ORZ03205.1 - 0.028 14.4 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PH_11 PF15413.6 ORZ03205.1 - 0.065 13.7 10.0 1 9.8 1.1 4.0 3 1 1 4 4 4 0 Pleckstrin homology domain EF-hand_1 PF00036.32 ORZ03206.1 - 1.2e-24 84.0 9.8 8.6e-07 28.1 0.1 5.8 6 1 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 ORZ03206.1 - 6.9e-24 84.1 4.6 2e-10 40.9 0.0 3.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORZ03206.1 - 2.6e-23 79.9 6.8 2.2e-06 27.1 0.0 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 ORZ03206.1 - 6.3e-18 64.4 8.8 6.5e-09 35.5 0.0 4.9 3 3 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 ORZ03206.1 - 7.5e-18 63.2 8.4 4e-05 22.9 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 ORZ03206.1 - 8.9e-05 22.7 0.0 2.1 8.7 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain DUF5640 PF18692.1 ORZ03206.1 - 0.0014 18.6 2.2 0.0056 16.7 0.4 2.5 1 1 2 3 3 3 1 Family of unknown function (DUF5640) Caleosin PF05042.13 ORZ03206.1 - 0.15 12.0 4.4 1.3 8.9 1.3 3.2 1 1 2 3 3 3 0 Caleosin related protein EF-hand_14 PF17959.1 ORZ03206.1 - 0.19 12.1 0.1 0.77 10.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Nup35_RRM PF05172.13 ORZ03206.1 - 0.19 11.7 0.4 0.56 10.2 0.4 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EF-hand_4 PF12763.7 ORZ03206.1 - 0.38 10.7 2.3 1.1 9.3 0.4 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SDA1 PF05285.12 ORZ03208.1 - 0.16 11.4 19.1 0.014 14.9 13.0 2.0 2 0 0 2 2 2 0 SDA1 TPR_1 PF00515.28 ORZ03209.1 - 8e-16 57.1 6.4 0.00029 20.5 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ03209.1 - 5.9e-13 48.3 6.1 0.00031 20.3 0.5 4.5 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.17 ORZ03209.1 - 3.3e-12 45.5 9.8 0.0011 18.9 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ03209.1 - 1.5e-09 38.2 7.0 4.5e-06 27.1 0.3 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ03209.1 - 2.9e-08 34.2 6.5 0.0022 18.6 0.2 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORZ03209.1 - 6.7e-08 32.8 1.2 0.0049 17.2 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ03209.1 - 8e-08 32.5 9.6 0.16 12.8 0.0 5.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ03209.1 - 8.6e-08 32.1 5.4 0.0013 19.0 0.3 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ03209.1 - 2.3e-06 27.3 5.9 0.56 10.6 0.1 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORZ03209.1 - 9.6e-06 25.7 5.7 0.03 14.5 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ03209.1 - 8.1e-05 22.4 8.3 0.095 12.8 0.3 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ03209.1 - 0.0017 18.6 8.6 0.062 13.6 1.8 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ03209.1 - 0.0018 18.4 0.5 0.0018 18.4 0.5 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF1641 PF07849.11 ORZ03209.1 - 0.019 14.8 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TPR_4 PF07721.14 ORZ03209.1 - 0.019 15.5 0.1 0.085 13.5 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ03209.1 - 0.025 15.2 1.5 5.2 7.9 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 ORZ03209.1 - 0.046 12.7 0.6 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) ERCC4 PF02732.15 ORZ03210.1 - 1.5e-17 64.2 0.0 2.8e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain OmpH PF03938.14 ORZ03210.1 - 0.055 13.8 0.3 13 6.2 0.0 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2256 PF10013.9 ORZ03210.1 - 6.9 6.9 6.7 2.1 8.6 3.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) CUE PF02845.16 ORZ03211.1 - 0.0085 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain P16-Arc PF04699.14 ORZ03212.1 - 1.8e-40 138.8 0.3 3.6e-40 137.9 0.3 1.4 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) XRN1_D1 PF18332.1 ORZ03213.1 - 1e-60 204.8 0.2 1.7e-60 204.1 0.2 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 ORZ03213.1 - 1.2e-22 79.9 0.0 3.5e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 ORZ03213.1 - 1.4e-21 76.3 0.1 3e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN_M PF17846.1 ORZ03213.1 - 1.7e-21 76.7 0.0 3.1e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Xrn1 helical domain Lactamase_B PF00753.27 ORZ03214.1 - 4e-16 59.6 2.8 1.7e-15 57.5 2.8 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORZ03214.1 - 3.7e-07 29.9 0.9 8e-07 28.8 0.9 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 ORZ03214.1 - 0.00023 21.1 0.5 0.00064 19.7 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Phage_hub_GP28 PF11110.8 ORZ03214.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Baseplate hub distal subunit Cu_amine_oxid PF01179.20 ORZ03215.1 - 1.1e-159 531.8 1.0 1.3e-159 531.6 1.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORZ03215.1 - 3.8e-20 72.2 0.2 1.1e-18 67.5 0.1 2.5 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ORZ03215.1 - 4.5e-08 33.2 0.1 1.1e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Pkinase PF00069.25 ORZ03216.1 - 1.8e-26 93.1 0.0 2.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03216.1 - 6.8e-12 45.2 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORZ03216.1 - 1.8e-07 30.3 0.0 2.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Band_7 PF01145.25 ORZ03217.1 - 1.1e-30 107.0 0.4 1.1e-30 107.0 0.4 1.8 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 ORZ03217.1 - 1.2e-25 89.3 2.4 1.2e-25 89.3 2.4 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 T2SSM PF04612.12 ORZ03217.1 - 0.25 11.4 5.4 6.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Kinesin PF00225.23 ORZ03218.1 - 0.00054 19.0 0.0 0.00054 19.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain BetR PF08667.10 ORZ03219.1 - 0.06 13.4 0.2 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 BetR domain SHE3 PF17078.5 ORZ03220.1 - 0.0043 16.8 12.4 0.0043 16.8 12.4 2.2 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 Tup_N PF08581.10 ORZ03220.1 - 0.088 13.1 21.5 0.81 10.0 7.5 3.5 3 0 0 3 3 3 0 Tup N-terminal DUF3179 PF11376.8 ORZ03220.1 - 0.14 11.5 6.0 0.19 11.1 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) Golgin_A5 PF09787.9 ORZ03220.1 - 1.3 8.4 26.7 2 7.8 16.3 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3584 PF12128.8 ORZ03220.1 - 1.6 6.2 31.6 0.47 7.9 22.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 ORZ03220.1 - 2.5 8.2 35.9 0.57 10.2 2.9 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Glutaredoxin2_C PF04399.13 ORZ03220.1 - 3.6 7.4 9.2 1.6 8.6 0.4 3.0 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain MPS2 PF17060.5 ORZ03220.1 - 6.6 5.9 14.2 0.32 10.2 8.7 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF4200 PF13863.6 ORZ03220.1 - 7.6 7.0 35.0 1.1 9.7 2.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) ING PF12998.7 ORZ03220.1 - 9 7.0 13.8 9.1 6.9 6.5 3.3 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF4407 PF14362.6 ORZ03220.1 - 9.2 5.5 30.4 0.39 10.0 10.5 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) FHA PF00498.26 ORZ03221.1 - 1.2e-15 57.6 0.1 2.4e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORZ03221.1 - 4.1e-09 36.0 6.4 4.1e-09 36.0 6.4 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 ORZ03221.1 - 1.3e-07 31.9 12.6 2.5e-07 30.9 12.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORZ03221.1 - 5.4e-05 23.4 8.7 0.00014 22.1 8.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.5 ORZ03221.1 - 0.00019 21.7 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 ORZ03221.1 - 0.0028 17.6 4.4 0.0055 16.7 4.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORZ03221.1 - 0.0064 16.4 12.2 0.018 15.0 12.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORZ03221.1 - 0.014 15.2 14.4 0.027 14.3 14.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ03221.1 - 0.016 15.1 12.9 0.033 14.1 12.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 ORZ03221.1 - 0.55 10.5 6.7 0.2 11.9 3.8 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 ORZ03221.1 - 2.6 7.8 8.3 7.8 6.2 8.5 1.7 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 ORZ03221.1 - 3 7.8 8.8 5.9 6.9 8.8 1.5 1 0 0 1 1 1 0 PHD-finger Ribosomal_L32e PF01655.18 ORZ03222.1 - 9.6e-51 170.7 1.0 1.2e-50 170.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 fn1 PF00039.18 ORZ03222.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Fibronectin type I domain Cation_efflux PF01545.21 ORZ03223.1 - 4.7e-49 166.8 5.9 6.2e-49 166.4 5.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORZ03223.1 - 1.6e-10 41.0 1.2 3.6e-10 39.8 1.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Steroid_dh PF02544.16 ORZ03224.1 - 2.1e-43 147.9 1.8 2.1e-43 147.9 1.8 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ORZ03224.1 - 3.2e-08 33.4 0.4 6.2e-08 32.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORZ03224.1 - 0.032 14.6 0.6 0.12 12.8 0.1 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Myb_DNA-binding PF00249.31 ORZ03225.1 - 1.6e-43 146.6 12.5 8.2e-14 51.5 1.8 5.1 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORZ03225.1 - 1.6e-40 137.1 6.9 1.2e-11 44.7 0.4 4.1 2 1 2 4 4 4 4 Myb-like DNA-binding domain SLIDE PF09111.10 ORZ03225.1 - 1.2e-07 31.8 0.0 0.33 11.0 0.0 3.5 2 1 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 ORZ03225.1 - 6.1e-07 29.3 1.9 0.19 11.6 0.0 4.4 2 1 3 5 5 5 3 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORZ03225.1 - 1.7e-06 28.2 5.3 0.041 14.1 0.2 3.9 2 2 2 4 4 4 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 ORZ03225.1 - 0.0065 16.6 1.0 5.5 7.3 0.0 4.2 4 1 0 4 4 4 1 Rap1 Myb domain WIYLD PF10440.9 ORZ03225.1 - 0.02 14.6 0.2 5.6 6.8 0.0 3.6 4 0 0 4 4 4 0 Ubiquitin-binding WIYLD domain Myb_DNA-bind_5 PF13873.6 ORZ03225.1 - 0.061 13.4 2.0 78 3.5 0.2 4.0 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain FMN_dh PF01070.18 ORZ03226.1 - 3.8e-120 401.1 0.2 4.6e-120 400.8 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORZ03226.1 - 4.4e-25 87.6 0.0 9.3e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ORZ03226.1 - 2.4e-09 36.8 0.0 4.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORZ03226.1 - 0.00047 19.3 0.6 0.0017 17.4 0.2 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ORZ03226.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Ras PF00071.22 ORZ03227.1 - 2.7e-67 225.4 0.0 3.1e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ03227.1 - 7.2e-35 119.8 0.0 1e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ03227.1 - 8.3e-15 54.7 0.0 9.8e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORZ03227.1 - 6e-06 25.9 0.1 1.7e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORZ03227.1 - 5.3e-05 22.7 0.0 6.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORZ03227.1 - 0.00013 21.9 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORZ03227.1 - 0.00022 20.7 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORZ03227.1 - 0.00038 20.5 0.0 0.00073 19.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORZ03227.1 - 0.0032 17.0 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.6 ORZ03227.1 - 0.038 13.7 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORZ03227.1 - 0.065 13.6 0.0 0.076 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 ORZ03227.1 - 0.072 13.5 0.0 3.9 7.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 ORZ03227.1 - 0.087 11.9 0.0 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain F-box-like PF12937.7 ORZ03228.1 - 4.7e-09 36.0 0.1 1.3e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORZ03228.1 - 1e-07 31.4 10.1 0.49 10.6 0.0 8.0 8 0 0 8 8 8 2 Leucine Rich repeat F-box PF00646.33 ORZ03228.1 - 8.6e-07 28.7 0.0 2.8e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ORZ03228.1 - 0.00013 22.3 4.2 12 6.5 1.4 5.8 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) DUF4632 PF15451.6 ORZ03228.1 - 0.28 11.3 3.1 2 8.5 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) LRR_1 PF00560.33 ORZ03228.1 - 8.5 7.4 20.2 50 5.0 0.1 6.9 6 1 0 6 6 6 0 Leucine Rich Repeat HMGL-like PF00682.19 ORZ03229.1 - 8.6e-79 264.8 0.4 1.7e-78 263.8 0.4 1.5 1 0 0 1 1 1 1 HMGL-like DHHC PF01529.20 ORZ03230.1 - 8.4e-31 106.8 16.2 8.4e-31 106.8 16.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase SHR3_chaperone PF08229.11 ORZ03230.1 - 0.76 8.7 8.9 0.074 12.0 4.3 1.6 2 0 0 2 2 2 0 ER membrane protein SH3 PGAP1 PF07819.13 ORZ03231.1 - 2.3e-82 276.2 0.0 3.3e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORZ03231.1 - 7.3e-05 23.5 0.0 0.00019 22.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORZ03231.1 - 0.00011 21.9 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 ORZ03231.1 - 0.0029 17.2 0.1 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ORZ03231.1 - 0.0045 16.3 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 ORZ03231.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LAT PF15234.6 ORZ03231.1 - 0.037 13.8 0.0 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells Lipase_3 PF01764.25 ORZ03231.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 ORZ03231.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ninjurin PF04923.12 ORZ03231.1 - 2.2 8.3 4.6 0.67 9.9 0.8 2.1 2 0 0 2 2 2 0 Ninjurin TPR_8 PF13181.6 ORZ03232.1 - 5.7e-13 48.0 0.2 0.0007 19.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ03232.1 - 1.2e-11 43.8 0.1 0.0068 16.4 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ03232.1 - 3.9e-10 39.1 0.0 0.002 17.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ03232.1 - 4.8e-07 30.0 0.2 0.0017 18.6 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-MYND PF01753.18 ORZ03232.1 - 9.1e-07 28.9 12.2 1.9e-06 27.9 12.2 1.6 1 0 0 1 1 1 1 MYND finger TPR_9 PF13371.6 ORZ03232.1 - 7.4e-05 22.8 0.0 0.0014 18.8 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ03232.1 - 0.0006 20.4 0.0 0.38 11.7 0.0 4.0 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ03232.1 - 0.0017 18.6 0.0 0.33 11.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ03232.1 - 0.0048 17.4 0.1 0.45 11.1 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ03232.1 - 0.018 15.6 0.1 29 5.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ03232.1 - 0.026 14.2 0.0 0.097 12.4 0.0 2.1 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 ORZ03232.1 - 0.048 13.7 1.8 0.17 12.0 0.0 3.0 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 ORZ03232.1 - 0.054 13.6 0.3 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) P16-Arc PF04699.14 ORZ03232.1 - 0.08 13.4 2.0 0.093 13.2 0.1 2.0 2 1 1 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) TPR_16 PF13432.6 ORZ03232.1 - 0.088 13.5 0.0 13 6.5 0.0 3.2 2 1 1 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 ORZ03233.1 - 6.3e-09 35.8 11.9 1.2e-08 34.9 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AOX PF01786.17 ORZ03234.1 - 9.3e-80 267.2 0.9 1.2e-79 266.9 0.9 1.0 1 0 0 1 1 1 1 Alternative oxidase Presenilin PF01080.17 ORZ03235.1 - 2.1e-86 290.2 0.1 2.4e-86 290.0 0.1 1.0 1 0 0 1 1 1 1 Presenilin SPP PF06550.11 ORZ03235.1 - 0.002 17.7 0.2 0.002 17.7 0.2 1.7 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease DDDD PF10161.9 ORZ03235.1 - 0.53 10.1 1.7 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Putative mitochondrial precursor protein zf-MYND PF01753.18 ORZ03236.1 - 4.9e-07 29.7 12.0 1.2e-06 28.5 12.0 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORZ03236.1 - 6.1e-05 22.8 7.3 0.00013 21.8 7.3 1.6 1 0 0 1 1 1 1 HIT zinc finger Presenilin PF01080.17 ORZ03236.1 - 0.089 11.5 0.2 0.089 11.5 0.2 2.0 1 1 1 2 2 2 0 Presenilin zf-B_box PF00643.24 ORZ03236.1 - 5.7 7.2 9.8 3.8 7.7 7.9 1.8 1 1 0 1 1 1 0 B-box zinc finger zf-C2H2 PF00096.26 ORZ03238.1 - 2.4e-17 62.3 18.0 4.2e-08 33.2 1.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03238.1 - 3.5e-12 46.1 14.6 0.00031 21.3 0.7 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORZ03238.1 - 5.3e-11 42.4 19.2 1.1e-07 31.9 1.7 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ03238.1 - 2.5e-07 30.5 7.8 0.03 14.3 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORZ03238.1 - 6.5e-06 26.3 1.5 0.29 11.5 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 ORZ03238.1 - 0.00033 20.7 4.8 0.41 10.8 2.6 2.8 2 1 1 3 3 3 3 Zinc ribbon domain zf-C2HE PF16278.5 ORZ03238.1 - 0.0015 19.0 4.1 0.14 12.6 0.3 2.3 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORZ03238.1 - 0.0015 18.2 6.7 0.05 13.4 0.5 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf_UBZ PF18439.1 ORZ03238.1 - 0.0029 17.2 4.1 0.98 9.1 0.4 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger IBR PF01485.21 ORZ03238.1 - 0.0091 16.2 3.3 0.0091 16.2 3.3 2.0 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain C1_4 PF07975.12 ORZ03238.1 - 0.012 15.8 0.9 0.012 15.8 0.9 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain DZR PF12773.7 ORZ03238.1 - 0.017 15.2 5.2 0.046 13.7 5.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon LIM PF00412.22 ORZ03238.1 - 0.02 15.1 4.0 0.039 14.2 3.4 1.7 2 0 0 2 2 2 0 LIM domain XPA_N PF01286.18 ORZ03238.1 - 0.022 14.8 0.5 12 6.1 0.0 2.9 3 0 0 3 3 3 0 XPA protein N-terminal zf_ZIC PF18366.1 ORZ03238.1 - 0.029 14.5 2.9 7.9 6.7 0.0 3.1 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 ORZ03238.1 - 0.031 14.5 5.4 0.096 13.0 5.4 1.7 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-LYAR PF08790.11 ORZ03238.1 - 0.032 14.1 5.4 1.9 8.4 0.0 3.4 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2HC_2 PF13913.6 ORZ03238.1 - 0.037 13.9 0.9 0.037 13.9 0.9 3.5 4 0 0 4 4 3 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 ORZ03238.1 - 0.044 14.5 1.7 0.24 12.1 0.4 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 ORZ03238.1 - 0.049 14.4 2.2 0.056 14.2 1.6 1.4 1 1 0 1 1 1 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 ORZ03238.1 - 0.075 13.0 2.9 4.2 7.4 2.9 2.3 1 1 0 1 1 1 0 zinc-ribbons Zn_ribbon_recom PF13408.6 ORZ03238.1 - 0.12 12.9 8.1 0.13 12.8 3.9 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain FYVE PF01363.21 ORZ03238.1 - 0.14 12.3 7.2 0.26 11.4 7.1 1.5 1 1 1 2 2 2 0 FYVE zinc finger zf-met PF12874.7 ORZ03238.1 - 0.19 12.1 6.6 11 6.6 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.7 ORZ03238.1 - 0.2 11.7 10.2 0.2 11.7 4.8 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-AN1 PF01428.16 ORZ03238.1 - 0.43 10.8 12.7 2 8.6 5.9 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger zf_C2H2_ZHX PF18387.1 ORZ03238.1 - 0.51 10.0 5.9 1.1 9.0 0.0 2.9 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DNA_RNApol_7kD PF03604.13 ORZ03238.1 - 1.1 9.0 5.1 25 4.6 0.1 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Ogr_Delta PF04606.12 ORZ03238.1 - 1.3 9.0 9.4 0.19 11.7 2.0 2.6 1 1 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_10 PF10058.9 ORZ03238.1 - 2.7 7.8 6.4 5.9 6.7 0.1 2.4 3 0 0 3 3 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TFIIS_C PF01096.18 ORZ03238.1 - 3.7 7.5 7.3 9.4 6.2 0.1 2.8 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Rubredoxin_2 PF18073.1 ORZ03238.1 - 6.4 6.6 12.4 1.7 8.4 1.1 3.0 4 0 0 4 4 3 0 Rubredoxin metal binding domain Zn_ribbon_SprT PF17283.2 ORZ03238.1 - 6.9 6.7 15.7 1.7 8.7 9.0 2.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DUF2256 PF10013.9 ORZ03238.1 - 7.3 6.8 10.3 6.4 7.0 0.6 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_4 PF13717.6 ORZ03238.1 - 8.5 6.4 8.3 12 6.0 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain PALP PF00291.25 ORZ03241.1 - 1.8e-78 263.9 1.6 2.6e-78 263.4 1.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ORZ03241.1 - 7.2e-44 147.5 0.0 1.5e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Mqo PF06039.15 ORZ03241.1 - 0.067 11.7 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) MqsR_toxin PF15723.5 ORZ03241.1 - 0.12 12.7 0.0 0.43 11.0 0.0 2.0 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA CBFD_NFYB_HMF PF00808.23 ORZ03243.1 - 3.3e-13 49.7 0.3 4.3e-13 49.3 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORZ03243.1 - 1.5e-05 25.3 0.1 1.8e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORZ03243.1 - 0.025 14.7 0.1 0.027 14.6 0.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF3482 PF11981.8 ORZ03244.1 - 0.055 12.9 1.8 0.066 12.6 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) GLTP PF08718.11 ORZ03244.1 - 0.12 12.6 2.8 0.16 12.3 2.8 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) UPF0052 PF01933.18 ORZ03245.1 - 7.9e-47 159.9 0.0 9.4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PHD_3 PF13922.6 ORZ03246.1 - 0.26 11.7 4.4 0.13 12.7 1.8 1.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx HLH PF00010.26 ORZ03247.1 - 2.4e-12 46.6 2.4 4.8e-12 45.7 2.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SprA-related PF12118.8 ORZ03247.1 - 0.00026 20.2 8.1 0.00031 20.0 8.1 1.2 1 0 0 1 1 1 1 SprA-related family PhoU_div PF01865.16 ORZ03247.1 - 0.0059 16.0 1.1 0.011 15.1 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF47 m04gp34like PF12216.8 ORZ03247.1 - 0.4 10.2 4.0 0.56 9.7 2.6 1.9 1 1 1 2 2 2 0 Immune evasion protein EBP50_C PF09007.11 ORZ03247.1 - 3.4 8.7 11.8 0.66 11.0 8.0 1.7 2 0 0 2 2 2 0 EBP50, C-terminal YabA PF06156.13 ORZ03247.1 - 3.8 8.2 13.4 0.36 11.5 5.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA NRBF2 PF08961.10 ORZ03247.1 - 6.8 6.2 12.8 0.33 10.5 3.0 2.1 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Syntaxin PF00804.25 ORZ03248.1 - 4.9e-19 68.8 17.7 8.3e-19 68.1 17.7 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORZ03248.1 - 2.1e-10 40.5 3.3 3.1e-10 39.9 0.6 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 ORZ03248.1 - 0.00039 20.7 13.6 0.00069 19.9 8.0 2.4 2 0 0 2 2 2 1 Syntaxin-like protein ODV-E18 PF10717.9 ORZ03248.1 - 0.0089 15.9 0.2 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF3671 PF12420.8 ORZ03248.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF21 PF01595.20 ORZ03248.1 - 0.044 13.5 1.0 0.17 11.6 0.6 2.2 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Med30 PF11315.8 ORZ03248.1 - 0.061 13.5 5.3 0.55 10.4 0.6 2.5 2 0 0 2 2 2 0 Mediator complex subunit 30 DUF5345 PF17280.2 ORZ03248.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5345) FIVAR PF07554.13 ORZ03248.1 - 0.16 12.8 5.6 0.89 10.4 0.0 3.5 2 1 1 3 3 3 0 FIVAR domain ISG65-75 PF11727.8 ORZ03248.1 - 0.31 10.2 9.9 0.74 9.0 1.7 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF2116 PF09889.9 ORZ03248.1 - 0.43 10.6 2.2 1 9.4 2.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2207 PF09972.9 ORZ03248.1 - 0.58 8.9 3.8 0.53 9.0 0.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) T2SSF PF00482.23 ORZ03248.1 - 0.62 10.0 2.7 0.74 9.8 0.3 2.3 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F DASH_Dam1 PF08653.10 ORZ03248.1 - 0.84 9.5 2.7 8.1 6.3 0.2 2.7 3 0 0 3 3 2 0 DASH complex subunit Dam1 ZnuA PF01297.17 ORZ03248.1 - 2 7.8 7.8 2.1 7.7 6.4 1.7 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic GP41 PF00517.17 ORZ03248.1 - 2.3 8.1 6.5 0.37 10.7 1.7 2.2 2 1 0 2 2 2 0 Retroviral envelope protein DUF3347 PF11827.8 ORZ03248.1 - 2.8 8.1 9.6 2.7 8.2 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) NPV_P10 PF05531.12 ORZ03248.1 - 3.4 8.2 6.4 6.4 7.3 0.5 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 ORZ03248.1 - 3.7 8.0 8.4 5.4 7.5 0.0 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.6 ORZ03248.1 - 9.1 6.8 8.3 0.98 9.9 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) DnaJ PF00226.31 ORZ03249.1 - 3.7e-17 62.2 0.1 9.4e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Piwi PF02171.17 ORZ03250.1 - 9.3e-108 360.0 0.0 1.4e-107 359.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORZ03250.1 - 1.5e-26 93.7 0.0 1e-25 90.9 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of argonaute PAZ PF02170.22 ORZ03250.1 - 1.9e-23 82.8 0.1 3.9e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 ORZ03250.1 - 3e-20 71.6 0.0 7.3e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 ORZ03250.1 - 1.1e-14 54.5 0.0 2.9e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 ORZ03250.1 - 1.2e-11 44.8 0.1 5.1e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Mid domain of argonaute VipB PF05943.12 ORZ03250.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath ABC_membrane PF00664.23 ORZ03251.1 - 1.2e-52 179.2 23.0 1.4e-30 106.8 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORZ03251.1 - 3e-49 167.1 0.0 3.5e-28 98.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORZ03251.1 - 2.2e-08 33.8 0.5 0.028 13.8 0.1 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORZ03251.1 - 6.7e-07 29.8 0.5 0.017 15.5 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 ORZ03251.1 - 6.9e-06 26.1 0.9 0.27 11.0 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORZ03251.1 - 1.9e-05 24.9 0.2 0.25 11.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORZ03251.1 - 5.1e-05 23.9 0.0 0.025 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORZ03251.1 - 0.00023 21.6 0.0 0.022 15.2 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 ORZ03251.1 - 0.00048 19.3 0.0 0.0042 16.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 ORZ03251.1 - 0.0008 19.1 0.0 0.43 10.4 0.0 3.2 3 0 0 3 3 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORZ03251.1 - 0.00095 19.2 0.7 2.1 8.4 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 ORZ03251.1 - 0.0026 17.4 0.0 0.2 11.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORZ03251.1 - 0.0071 16.3 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 ORZ03251.1 - 0.012 15.4 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORZ03251.1 - 0.024 14.6 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORZ03251.1 - 0.038 13.5 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORZ03251.1 - 0.038 14.4 0.1 0.52 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 ORZ03251.1 - 0.042 13.2 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 ORZ03251.1 - 0.063 13.0 0.0 11 5.7 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 ORZ03251.1 - 0.076 13.1 0.8 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 ORZ03251.1 - 0.11 12.6 1.5 8.9 6.3 0.0 2.8 2 1 0 2 2 2 0 Dynamin family DUF4381 PF14316.6 ORZ03251.1 - 0.11 12.8 3.7 0.17 12.2 1.5 2.5 3 0 0 3 3 1 0 Domain of unknown function (DUF4381) Zeta_toxin PF06414.12 ORZ03251.1 - 0.11 11.7 0.2 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 ORZ03251.1 - 0.13 12.2 0.7 0.71 9.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.29 ORZ03251.1 - 0.15 11.8 1.3 18 5.1 0.0 3.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase cobW PF02492.19 ORZ03251.1 - 0.19 11.3 2.0 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 ORZ03251.1 - 0.23 10.6 1.1 0.95 8.6 0.1 2.2 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 ORZ03251.1 - 0.25 11.1 0.5 3.9 7.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORZ03251.1 - 0.34 10.6 1.1 2 8.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain YlaC PF10777.9 ORZ03251.1 - 0.37 10.6 3.1 0.53 10.1 0.0 2.9 4 0 0 4 4 1 0 Inner membrane protein YlaC AAA_33 PF13671.6 ORZ03251.1 - 0.57 10.3 1.9 2.7 8.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF2770 PF10968.8 ORZ03251.1 - 8.4 6.5 6.6 5.6 7.0 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) CP2 PF04516.15 ORZ03252.1 - 9.8e-54 182.1 0.0 1.4e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DUF2009 PF09418.10 ORZ03253.1 - 9e-213 707.4 0.0 1.1e-212 707.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Sec23_trunk PF04811.15 ORZ03254.1 - 1.5e-73 247.4 0.0 2.3e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORZ03254.1 - 3.1e-23 81.5 0.1 6.5e-23 80.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORZ03254.1 - 8.7e-18 64.9 0.0 2.3e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORZ03254.1 - 2.5e-16 59.4 2.6 4.9e-16 58.5 2.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORZ03254.1 - 4.8e-11 42.4 0.8 9.5e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat VWA_2 PF13519.6 ORZ03254.1 - 0.0033 18.0 0.1 0.63 10.7 0.1 3.4 3 0 0 3 3 3 1 von Willebrand factor type A domain Vps36-NZF-N PF16988.5 ORZ03254.1 - 0.041 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA PF00092.28 ORZ03254.1 - 0.074 13.3 0.6 0.77 10.0 0.6 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain Abhydrolase_6 PF12697.7 ORZ03255.1 - 7.2e-28 98.7 0.2 9e-28 98.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORZ03255.1 - 1.2e-12 48.0 0.1 1.6e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORZ03255.1 - 3.3e-11 42.9 0.4 4.9e-11 42.3 0.4 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORZ03255.1 - 3.6e-05 24.0 0.0 7.6e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 ORZ03255.1 - 0.0014 17.6 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 ORZ03255.1 - 0.0037 17.1 0.5 0.01 15.7 0.1 1.9 2 1 0 2 2 2 1 Serine hydrolase Palm_thioest PF02089.15 ORZ03255.1 - 0.0042 17.0 0.1 0.0055 16.6 0.1 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Methyltransf_32 PF13679.6 ORZ03255.1 - 0.0048 16.9 0.0 0.017 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PGAP1 PF07819.13 ORZ03255.1 - 0.012 15.3 0.7 0.031 14.0 0.3 1.7 1 1 1 2 2 2 0 PGAP1-like protein LIDHydrolase PF10230.9 ORZ03255.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 ORZ03255.1 - 0.065 13.0 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 ORZ03255.1 - 0.13 11.8 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Glyco_hydro_16 PF00722.21 ORZ03256.1 - 1.6e-07 30.9 0.0 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CP2 PF04516.15 ORZ03258.1 - 5.1e-35 120.8 0.0 7.5e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor ATP-synt_ab PF00006.25 ORZ03259.1 - 7.5e-64 215.3 0.0 1.4e-63 214.4 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORZ03259.1 - 1.7e-24 86.1 3.2 3.3e-24 85.2 2.3 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NACHT PF05729.12 ORZ03259.1 - 0.011 15.6 0.1 0.026 14.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 ORZ03259.1 - 0.012 14.8 1.0 0.016 14.4 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 ORZ03259.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORZ03259.1 - 0.028 14.3 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ORZ03259.1 - 0.034 14.5 0.7 0.11 12.9 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 ORZ03259.1 - 0.036 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.29 ORZ03259.1 - 0.05 14.0 0.0 0.45 10.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORZ03259.1 - 0.079 13.3 0.5 0.29 11.5 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORZ03259.1 - 0.13 12.6 0.1 1 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORZ03259.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T3SS_ATPase_C PF18269.1 ORZ03259.1 - 0.14 12.0 0.3 0.92 9.4 0.3 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RnfC_N PF13375.6 ORZ03259.1 - 0.15 12.0 0.3 0.4 10.7 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain WD40 PF00400.32 ORZ03260.1 - 3.6e-69 227.0 26.7 1.3e-07 32.2 0.1 11.9 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.11 ORZ03260.1 - 7.7e-51 171.7 0.2 1.5e-50 170.8 0.2 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 ORZ03260.1 - 5.5e-20 71.5 13.6 0.00097 19.4 0.0 9.9 3 2 5 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORZ03260.1 - 1.9e-09 36.7 19.8 1.1 7.8 0.6 9.1 4 2 4 8 8 8 6 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORZ03260.1 - 3.9e-07 29.4 15.2 0.024 13.6 0.0 7.0 1 1 7 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 ORZ03260.1 - 9.1e-06 24.7 2.7 3.7 6.2 0.0 5.8 1 1 1 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.6 ORZ03260.1 - 1.2e-05 25.3 3.6 0.076 13.1 0.1 6.1 4 1 3 7 7 7 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 ORZ03260.1 - 2.9e-05 23.5 6.6 0.64 9.3 0.0 4.7 3 2 2 5 5 5 2 WD40-like domain Hira PF07569.11 ORZ03260.1 - 0.0062 16.3 4.9 0.18 11.5 0.0 4.8 5 2 0 5 5 5 1 TUP1-like enhancer of split Utp12 PF04003.12 ORZ03260.1 - 0.026 14.8 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 Dip2/Utp12 Family TAF6_C PF07571.13 ORZ03261.1 - 1.4e-31 108.7 0.0 5.1e-31 106.8 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 ORZ03261.1 - 3.6e-30 103.9 0.1 7.5e-30 102.9 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORZ03261.1 - 2.4e-05 24.7 0.2 0.00025 21.4 0.1 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ORZ03261.1 - 0.00011 22.3 0.2 0.00042 20.4 0.1 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 ORZ03261.1 - 0.0013 18.9 0.4 0.0053 17.0 0.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT_EZ PF13513.6 ORZ03261.1 - 0.028 14.9 0.7 1.3 9.6 0.0 3.3 4 0 0 4 4 4 0 HEAT-like repeat TFIID_20kDa PF03847.13 ORZ03261.1 - 0.051 14.1 0.2 0.38 11.3 0.2 2.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DUF664 PF04978.12 ORZ03261.1 - 0.47 10.9 2.9 2.2 8.7 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF664) Prefoldin_2 PF01920.20 ORZ03262.1 - 6.7e-06 26.0 5.2 6.8e-06 26.0 4.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit SIKE PF05769.11 ORZ03262.1 - 0.057 13.4 5.7 0.093 12.7 5.6 1.3 1 1 0 1 1 1 0 SIKE family DUF2950 PF11453.8 ORZ03262.1 - 0.074 12.2 0.7 0.08 12.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) PLDc PF00614.22 ORZ03263.1 - 2.6e-17 62.2 2.8 8.1e-10 38.5 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORZ03263.1 - 6.7e-16 58.4 0.0 1.3e-06 28.3 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PX PF00787.24 ORZ03263.1 - 7.7e-08 32.3 0.1 4.6e-07 29.8 0.0 2.4 3 0 0 3 3 3 1 PX domain Peroxin-13_N PF04088.13 ORZ03264.1 - 1.2e-47 161.8 0.0 2.4e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 ORZ03264.1 - 1.4e-11 43.8 0.0 2.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORZ03264.1 - 6.4e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORZ03264.1 - 4e-08 32.8 0.0 8.2e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ran_BP1 PF00638.18 ORZ03265.1 - 8.3e-15 55.1 1.0 2e-14 53.9 1.0 1.6 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 ORZ03265.1 - 0.0003 20.7 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 WH1 domain UNC-50 PF05216.13 ORZ03266.1 - 3.5e-94 314.5 23.3 4.1e-94 314.3 23.3 1.1 1 0 0 1 1 1 1 UNC-50 family PEPCK_ATP PF01293.20 ORZ03267.1 - 1.3e-223 742.8 0.0 1.6e-223 742.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 ORZ03267.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Gti1_Pac2 PF09729.9 ORZ03268.1 - 1.9e-43 148.6 8.1 3.7e-37 128.2 0.4 3.0 2 1 1 3 3 3 2 Gti1/Pac2 family Ceramidase PF05875.12 ORZ03269.1 - 5.8e-54 183.3 23.7 6.7e-54 183.1 23.7 1.0 1 0 0 1 1 1 1 Ceramidase PEP-CTERM PF07589.11 ORZ03269.1 - 1.3 9.2 4.0 0.46 10.6 0.8 2.0 2 0 0 2 2 2 0 PEP-CTERM motif Glyco_transf_49 PF13896.6 ORZ03271.1 - 2.6e-21 76.3 0.3 1.3e-13 51.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF1772 PF08592.11 ORZ03271.1 - 0.47 10.8 3.6 0.34 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) FYVE PF01363.21 ORZ03273.1 - 8.1e-15 54.7 10.1 2.1e-14 53.4 10.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger DDE_Tnp_ISL3 PF01610.17 ORZ03273.1 - 0.071 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Transposase SWIRM-assoc_2 PF16496.5 ORZ03273.1 - 0.61 8.9 5.9 1.1 8.1 5.9 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Fib_alpha PF08702.10 ORZ03274.1 - 0.01 16.0 0.4 0.01 16.0 0.4 2.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family SUIM_assoc PF16619.5 ORZ03274.1 - 0.065 13.3 15.0 0.28 11.3 5.3 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 ORZ03274.1 - 0.29 11.1 8.2 0.34 10.8 8.0 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 ORZ03274.1 - 7.2 5.7 8.6 0.46 9.6 2.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Zn_clus PF00172.18 ORZ03275.1 - 1.3e-08 34.9 11.8 2.1e-08 34.1 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrfB_Zn_ribbon PF07282.11 ORZ03276.1 - 0.059 13.3 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Choline_transpo PF04515.12 ORZ03277.1 - 1.3e-76 257.9 33.9 1.3e-76 257.9 33.9 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter SLC3A2_N PF16028.5 ORZ03277.1 - 0.065 12.8 0.0 0.39 10.3 0.0 2.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Pex14_N PF04695.13 ORZ03277.1 - 0.35 11.5 5.7 0.94 10.1 5.7 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 ORZ03278.1 - 3.7e-193 643.3 2.0 5.2e-193 642.8 2.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 ORZ03278.1 - 0.009 15.6 0.0 0.089 12.3 0.0 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus RRM_1 PF00076.22 ORZ03279.1 - 3e-16 59.0 0.0 4.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.6 ORZ03281.1 - 2.7e-19 69.7 0.0 7.7e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03281.1 - 3e-15 56.6 0.0 6.5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ03281.1 - 4.2e-13 49.5 0.0 6.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03281.1 - 5.8e-12 45.7 0.0 5.8e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ03281.1 - 3.7e-10 39.5 0.0 1.4e-08 34.4 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 ORZ03281.1 - 2.6e-09 36.7 0.1 3.7e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 ORZ03281.1 - 1.3e-07 32.3 0.0 5.7e-07 30.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORZ03281.1 - 5.3e-05 23.2 0.0 0.00011 22.1 0.0 1.5 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 ORZ03281.1 - 0.00057 19.4 0.0 0.0015 18.0 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 ORZ03281.1 - 0.0007 19.0 0.0 0.0021 17.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 ORZ03281.1 - 0.0026 17.9 0.1 0.0045 17.1 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 ORZ03281.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 ORZ03281.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 ORZ03281.1 - 0.099 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 ORZ03281.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) CNH PF00780.22 ORZ03282.1 - 5.6e-58 196.7 0.0 8.9e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORZ03282.1 - 2.7e-35 122.3 0.5 5.1e-35 121.3 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORZ03282.1 - 3.7e-34 117.7 0.0 8.1e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORZ03282.1 - 1.4e-10 41.1 0.0 2.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IL1 PF00340.19 ORZ03282.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Interleukin-1 / 18 Pkinase PF00069.25 ORZ03283.1 - 1.1e-72 244.6 0.0 1.6e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03283.1 - 9.4e-36 123.4 0.0 1.4e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 ORZ03283.1 - 3.5e-08 33.7 0.1 0.00021 21.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 ORZ03283.1 - 7.7e-06 25.4 0.0 1.7e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Act-Frag_cataly PF09192.10 ORZ03283.1 - 0.0043 16.5 0.1 0.0073 15.7 0.1 1.3 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic Pkinase_C PF00433.24 ORZ03283.1 - 0.0062 17.2 0.0 0.016 15.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 ORZ03283.1 - 0.0075 16.2 0.5 0.082 12.8 0.2 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family SUIM_assoc PF16619.5 ORZ03283.1 - 0.0094 16.0 3.2 0.0096 16.0 1.2 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Haspin_kinase PF12330.8 ORZ03283.1 - 0.05 12.5 0.1 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 ORZ03284.1 - 4.5e-27 95.1 0.0 4.8e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03284.1 - 1.5e-14 54.0 0.0 1.5e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03284.1 - 1.6e-06 27.7 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORZ03284.1 - 0.0029 17.2 0.0 0.0035 16.9 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORZ03284.1 - 0.0037 17.2 0.1 0.0057 16.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORZ03284.1 - 0.0051 16.2 0.1 0.0068 15.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORZ03284.1 - 0.0058 15.5 0.0 0.0059 15.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORZ03284.1 - 0.06 12.4 0.0 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 ORZ03284.1 - 0.24 11.0 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Polysacc_deac_1 PF01522.21 ORZ03285.1 - 1.6e-37 128.1 0.1 8.2e-37 125.9 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORZ03285.1 - 2.2e-05 23.8 0.1 7.9e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 LDcluster4 PF18306.1 ORZ03285.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family SAICAR_synt PF01259.18 ORZ03287.1 - 1.1e-103 346.2 0.0 1.3e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase CP2 PF04516.15 ORZ03288.1 - 5.1e-31 107.8 1.5 7.7e-29 100.6 1.5 2.5 1 1 0 1 1 1 1 CP2 transcription factor p450 PF00067.22 ORZ03289.1 - 7.5e-68 229.4 0.1 9.5e-68 229.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Clat_adaptor_s PF01217.20 ORZ03290.1 - 4.7e-57 191.9 2.5 5.2e-57 191.8 2.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 ORZ03290.1 - 0.01 15.4 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Ribosomal_S6e PF01092.19 ORZ03291.1 - 5.2e-60 200.9 0.1 5.2e-60 200.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e WD40 PF00400.32 ORZ03292.1 - 8.2e-59 194.2 10.8 6.8e-10 39.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORZ03292.1 - 1.1e-27 96.1 12.1 1.7e-27 95.5 12.1 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORZ03292.1 - 3.9e-21 75.1 0.0 0.0029 17.9 0.0 6.2 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ03292.1 - 1.2e-07 31.4 0.0 0.0027 17.1 0.0 3.9 5 0 0 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 ORZ03292.1 - 1.7e-06 27.3 0.0 0.75 8.7 0.0 5.1 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORZ03292.1 - 0.0029 16.2 0.2 0.06 11.9 0.3 2.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.11 ORZ03292.1 - 0.0041 17.0 0.0 0.25 11.2 0.0 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A CEP63 PF17045.5 ORZ03292.1 - 0.0081 16.1 4.7 0.013 15.4 4.7 1.3 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Nup160 PF11715.8 ORZ03292.1 - 0.012 14.3 0.3 0.9 8.1 0.0 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF5122 PF17164.4 ORZ03292.1 - 0.021 15.1 1.8 47 4.4 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller MMS1_N PF10433.9 ORZ03292.1 - 0.032 12.9 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleoporin_N PF08801.11 ORZ03292.1 - 0.069 11.9 0.0 8.1 5.1 0.0 3.5 1 1 0 1 1 1 0 Nup133 N terminal like Spc7 PF08317.11 ORZ03292.1 - 0.27 10.1 4.8 0.38 9.6 4.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 ORZ03292.1 - 0.43 10.8 7.6 0.71 10.1 7.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 ORZ03292.1 - 5.2 6.3 8.0 9.1 5.5 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPX2 PF06886.11 ORZ03292.1 - 5.2 7.4 8.8 6.7 7.0 7.8 1.6 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Usp PF00582.26 ORZ03294.1 - 3.1e-25 89.3 0.0 1.3e-24 87.3 0.0 1.8 1 1 0 1 1 1 1 Universal stress protein family SAC3_GANP PF03399.16 ORZ03295.1 - 3e-96 322.2 3.9 1e-95 320.5 3.9 1.9 1 0 0 1 1 1 1 SAC3/GANP family TFIIA PF03153.13 ORZ03295.1 - 0.1 12.6 44.7 0.52 10.3 10.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Gelsolin PF00626.22 ORZ03296.1 - 1.1e-26 92.5 0.0 2.9e-12 46.3 0.1 2.3 2 0 0 2 2 2 2 Gelsolin repeat CobW_C PF07683.14 ORZ03296.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain DUF1752 PF08550.10 ORZ03297.1 - 1.2e-13 50.6 0.5 2.4e-13 49.6 0.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pex26 PF07163.12 ORZ03297.1 - 0.0089 15.4 1.5 0.014 14.8 1.5 1.2 1 0 0 1 1 1 1 Pex26 protein GTSE1_N PF15259.6 ORZ03297.1 - 1.6 8.9 10.7 17 5.6 0.4 3.3 3 0 0 3 3 3 0 G-2 and S-phase expressed 1 DDE_Tnp_1_2 PF13586.6 ORZ03297.1 - 4.9 7.6 6.2 2.2 8.7 3.3 1.9 2 0 0 2 2 2 0 Transposase DDE domain Cyclin PF08613.11 ORZ03298.1 - 1.6e-09 38.3 1.0 1.6e-09 38.3 1.0 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORZ03298.1 - 2.4e-05 24.1 0.2 2.4e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2722 PF10846.8 ORZ03298.1 - 0.0042 16.1 4.7 0.0042 16.1 4.7 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) Hira PF07569.11 ORZ03299.1 - 0.003 17.3 0.2 0.0054 16.5 0.2 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40_3 PF15911.5 ORZ03299.1 - 0.15 12.1 0.1 0.38 10.8 0.1 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat DAO PF01266.24 ORZ03300.1 - 2.3e-25 89.9 0.1 2.7e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase CPSase_L_D2 PF02786.17 ORZ03300.1 - 0.19 11.2 0.1 0.94 8.9 0.0 2.0 2 1 1 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DAO PF01266.24 ORZ03301.1 - 4.8e-31 108.6 3.2 8.8e-31 107.8 3.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 ORZ03301.1 - 0.097 12.1 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 ORZ03301.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORZ03301.1 - 0.13 11.9 2.0 0.85 9.2 0.6 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.10 ORZ03301.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Pil1 PF13805.6 ORZ03302.1 - 1.3e-37 129.8 2.3 1.3e-37 129.8 2.3 2.2 3 0 0 3 3 3 1 Eisosome component PIL1 HHH_8 PF14716.6 ORZ03302.1 - 0.039 14.3 2.7 0.16 12.3 2.1 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain DDE_Tnp_IS240 PF13610.6 ORZ03302.1 - 0.45 10.7 3.3 1.9 8.7 0.6 2.7 2 0 0 2 2 2 0 DDE domain Rhomboid PF01694.22 ORZ03303.1 - 1e-25 90.5 14.7 1e-25 90.5 14.7 1.8 2 0 0 2 2 2 1 Rhomboid family DUF3756 PF12581.8 ORZ03303.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) Sod_Cu PF00080.20 ORZ03304.1 - 4.9e-50 169.4 7.0 5.7e-50 169.2 7.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 ORZ03304.1 - 0.079 13.9 2.5 0.13 13.3 2.4 1.4 1 1 0 1 1 1 0 CHRD domain T6PP_N PF18572.1 ORZ03305.1 - 0.021 14.7 0.8 3.6 7.5 0.0 3.0 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-F_leu_zip PF10473.9 ORZ03305.1 - 0.23 11.5 20.2 0.56 10.2 7.2 3.4 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 ORZ03305.1 - 0.34 11.2 13.2 0.74 10.1 0.4 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) Ran-binding PF05508.11 ORZ03305.1 - 1.5 7.7 7.2 1.5 7.8 0.7 2.8 3 0 0 3 3 3 0 RanGTP-binding protein Rx_N PF18052.1 ORZ03305.1 - 1.5 9.1 5.5 14 6.0 0.2 3.6 4 0 0 4 4 4 0 Rx N-terminal domain LMBR1 PF04791.16 ORZ03305.1 - 2.1 7.1 3.8 2.7 6.8 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 ORZ03305.1 - 4.6 7.8 24.3 1.7 9.1 5.6 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 ORZ03305.1 - 7.3 5.1 7.0 12 4.3 6.8 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Arrestin_C PF02752.22 ORZ03306.1 - 4.1e-24 85.5 0.3 7.4e-21 75.0 0.3 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORZ03306.1 - 1e-19 71.1 0.1 9.2e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORZ03306.1 - 5e-07 29.6 0.0 1.3e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Arrestin_N terminal like LRR_6 PF13516.6 ORZ03307.1 - 0.0033 17.4 4.2 1 9.6 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat F-box-like PF12937.7 ORZ03308.1 - 2.1e-05 24.3 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ03308.1 - 0.0004 20.2 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain B-block_TFIIIC PF04182.12 ORZ03309.1 - 4.9e-09 36.2 3.5 4.4e-08 33.2 0.1 3.0 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_36 PF13730.6 ORZ03309.1 - 0.0015 18.4 0.1 0.0057 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ORZ03309.1 - 0.0018 17.8 0.5 4.4 6.9 0.0 4.5 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ORZ03309.1 - 0.0063 16.4 0.0 0.045 13.7 0.0 2.6 2 0 0 2 2 2 1 MarR family LexA_DNA_bind PF01726.16 ORZ03309.1 - 0.012 15.4 0.0 0.042 13.6 0.0 1.9 1 0 0 1 1 1 0 LexA DNA binding domain RNA_pol_Rpc34 PF05158.12 ORZ03309.1 - 0.047 13.1 0.6 9.5 5.5 0.0 3.4 3 0 0 3 3 3 0 RNA polymerase Rpc34 subunit CheR_N PF03705.15 ORZ03309.1 - 0.061 13.0 1.3 0.26 11.1 1.3 2.2 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain MarR_2 PF12802.7 ORZ03309.1 - 0.088 12.7 0.1 0.59 10.1 0.0 2.5 2 0 0 2 2 2 0 MarR family Sulfotransfer_4 PF17784.1 ORZ03310.1 - 7.6e-59 199.1 0.0 8.9e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORZ03310.1 - 0.0076 16.7 0.1 0.36 11.2 0.0 2.4 2 1 1 3 3 3 1 Sulfotransferase family Bin3 PF06859.12 ORZ03311.1 - 2.6e-36 124.5 0.5 4.6e-36 123.7 0.2 1.6 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 ORZ03311.1 - 1.9e-10 40.8 0.0 2.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03311.1 - 1.6e-08 34.5 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03311.1 - 3.1e-08 34.1 0.0 0.001 19.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ03311.1 - 2.1e-07 31.6 0.0 0.016 15.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ03311.1 - 1.9e-06 28.6 0.0 1.6e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORZ03311.1 - 0.0078 15.5 0.1 0.22 10.8 0.1 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 ORZ03311.1 - 0.03 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.11 ORZ03311.1 - 0.14 11.0 0.1 0.39 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 ORZ03311.1 - 0.15 11.9 0.0 0.97 9.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain CoA_transf_3 PF02515.17 ORZ03312.1 - 2.8e-35 122.2 0.5 3.1e-32 112.1 0.2 2.2 2 0 0 2 2 2 2 CoA-transferase family III FKBP_C PF00254.28 ORZ03313.1 - 1.8e-18 66.7 0.0 3.8e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 ORZ03313.1 - 6.1e-14 51.2 0.6 9.4e-06 25.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ03313.1 - 4.5e-13 48.2 0.4 0.00032 20.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ03313.1 - 2.1e-08 33.7 1.8 0.029 14.0 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 ORZ03313.1 - 2.2e-08 33.7 0.3 0.0048 17.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORZ03313.1 - 4.1e-07 29.9 0.0 0.0052 16.8 0.0 2.9 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 ORZ03313.1 - 4.9e-06 27.0 0.0 1.4e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ03313.1 - 7.6e-06 26.1 0.4 0.58 10.5 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ03313.1 - 1.9e-05 25.1 0.1 0.0045 17.7 0.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ03313.1 - 3.6e-05 24.3 0.0 0.025 15.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ03313.1 - 0.00031 20.9 0.0 0.044 14.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ03313.1 - 0.00089 19.8 0.0 0.25 12.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ03313.1 - 0.0019 18.4 0.4 0.013 15.7 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORZ03313.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 ORZ03313.1 - 0.13 12.3 0.5 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 ORZ03314.1 - 2.7e-27 94.6 24.1 5e-08 33.4 0.6 8.1 9 1 0 9 9 9 5 Sel1 repeat TPR_1 PF00515.28 ORZ03314.1 - 0.00075 19.2 5.7 0.89 9.5 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ03314.1 - 0.0042 17.0 4.0 2.4 8.4 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ03314.1 - 0.017 15.4 5.9 7.1 7.0 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat PACT_coil_coil PF10495.9 ORZ03314.1 - 0.028 15.0 0.0 0.085 13.4 0.0 1.8 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Auxin_repressed PF05564.12 ORZ03314.1 - 0.073 13.8 0.5 0.2 12.4 0.2 1.8 2 0 0 2 2 2 0 Dormancy/auxin associated protein TPR_8 PF13181.6 ORZ03314.1 - 0.22 11.8 5.3 11 6.5 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat PAP_central PF04928.17 ORZ03315.1 - 1.6e-97 325.4 0.0 2.7e-97 324.6 0.0 1.4 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORZ03315.1 - 9.6e-26 90.4 0.0 1.7e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORZ03315.1 - 5.9e-06 26.5 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ORZ03315.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain Hexokinase_2 PF03727.16 ORZ03316.1 - 2.2e-67 227.0 0.0 2.8e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORZ03316.1 - 4.4e-45 154.0 0.0 6.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Questin_oxidase PF14027.6 ORZ03317.1 - 1.1e-38 133.7 0.0 1.3e-38 133.4 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like FMN_dh PF01070.18 ORZ03318.1 - 8.5e-127 423.0 0.1 1.1e-126 422.6 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORZ03318.1 - 3.1e-07 29.7 1.3 1.7e-06 27.3 0.5 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORZ03318.1 - 9.3e-05 21.7 0.0 0.00027 20.2 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 ORZ03318.1 - 0.00014 21.4 0.4 0.00022 20.7 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 ORZ03318.1 - 0.001 18.4 0.2 0.72 9.1 0.0 2.7 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ORZ03318.1 - 0.0039 16.7 0.2 0.038 13.4 0.0 2.4 2 1 1 3 3 3 1 Histidine biosynthesis protein TMP-TENI PF02581.17 ORZ03318.1 - 0.017 14.4 0.2 0.11 11.8 0.0 2.3 3 0 0 3 3 3 0 Thiamine monophosphate synthase DUF1363 PF07101.11 ORZ03318.1 - 0.091 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) G3P_antiterm PF04309.12 ORZ03318.1 - 0.12 11.8 0.0 8.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator RSN1_7TM PF02714.15 ORZ03319.1 - 1.1e-83 280.8 24.8 1.9e-83 280.0 24.8 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORZ03319.1 - 2.3e-35 121.6 1.4 2.3e-35 121.6 1.4 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORZ03319.1 - 1.4e-32 113.3 0.0 2.4e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORZ03319.1 - 9.2e-06 25.7 0.0 3.9e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Anoctamin PF04547.12 ORZ03319.1 - 0.0078 15.1 0.5 0.0078 15.1 0.5 2.3 1 1 0 2 2 2 1 Calcium-activated chloride channel PH_9 PF15410.6 ORZ03320.1 - 4.3e-06 27.1 0.2 0.00018 21.9 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORZ03320.1 - 1.6e-05 25.3 0.1 2.2e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 PH domain Cpn60_TCP1 PF00118.24 ORZ03321.1 - 2.4e-159 531.1 3.7 2.7e-159 530.9 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Synapsin_C PF02750.14 ORZ03321.1 - 0.11 12.0 0.3 0.19 11.2 0.3 1.4 1 0 0 1 1 1 0 Synapsin, ATP binding domain zf-C2H2 PF00096.26 ORZ03322.1 - 3.9e-08 33.3 6.4 0.0042 17.5 0.2 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03322.1 - 0.004 17.9 3.9 0.076 13.9 0.9 4.3 5 0 0 5 5 5 2 C2H2-type zinc finger SR-25 PF10500.9 ORZ03322.1 - 0.01 15.4 11.4 0.01 15.4 11.4 2.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Antimicrobial25 PF16839.5 ORZ03322.1 - 0.1 12.7 0.5 1 9.5 0.2 2.3 2 0 0 2 2 2 0 Nematode antimicrobial peptide FAM199X PF15814.5 ORZ03322.1 - 0.55 9.2 6.0 1 8.3 6.0 1.4 1 0 0 1 1 1 0 Protein family FAM199X LSM PF01423.22 ORZ03323.1 - 1.4e-18 66.3 1.9 1.8e-18 65.9 1.9 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORZ03323.1 - 0.022 14.9 0.1 0.03 14.5 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 ORZ03323.1 - 0.067 13.1 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) AIP3 PF03915.13 ORZ03324.1 - 1.6e-123 412.8 20.3 1.6e-123 412.8 20.3 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 Acetyltransf_8 PF13523.6 ORZ03324.1 - 0.0091 15.7 1.4 0.012 15.3 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1640 PF07798.11 ORZ03324.1 - 0.049 13.7 12.7 0.064 13.3 3.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Par3_HAL_N_term PF12053.8 ORZ03324.1 - 0.072 13.3 0.2 0.23 11.7 0.2 1.9 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins DUF2974 PF11187.8 ORZ03325.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RhoGEF PF00621.20 ORZ03326.1 - 1.1e-22 81.2 0.4 2.2e-22 80.2 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain ArfGap PF01412.18 ORZ03327.1 - 2.8e-30 104.8 0.3 2.8e-30 104.8 0.3 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 ORZ03327.1 - 1.2e-16 61.2 8.0 1.8e-16 60.6 8.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORZ03327.1 - 2.7e-12 47.1 0.4 7.1e-12 45.8 0.4 1.7 1 0 0 1 1 1 1 PH domain DUF3086 PF11285.8 ORZ03327.1 - 0.0012 18.0 1.4 0.012 14.7 3.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3086) Ank_3 PF13606.6 ORZ03327.1 - 0.16 12.6 0.1 2.7 8.8 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Cpn60_TCP1 PF00118.24 ORZ03328.1 - 6.3e-159 529.7 14.1 7.1e-159 529.5 14.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRCT PF00533.26 ORZ03328.1 - 0.088 13.2 0.2 5 7.6 0.0 2.9 2 1 1 3 3 3 0 BRCA1 C Terminus (BRCT) domain SWIRM PF04433.17 ORZ03329.1 - 5.8e-22 77.8 0.1 4.7e-21 74.9 0.1 2.5 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 ORZ03329.1 - 7.2e-14 51.7 0.6 7.2e-14 51.7 0.6 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain JAB PF01398.21 ORZ03329.1 - 1.8e-11 44.0 0.0 4.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-bind_6 PF13921.6 ORZ03329.1 - 3.6e-08 33.5 0.3 1.1e-07 32.0 0.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-JAB PF14464.6 ORZ03329.1 - 6.8e-08 32.3 0.1 1.7e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 ORZ03329.1 - 0.015 15.3 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) SLIDE PF09111.10 ORZ03329.1 - 0.024 14.7 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 SLIDE E1-E2_ATPase PF00122.20 ORZ03330.1 - 3.4e-50 170.1 4.7 9.6e-50 168.6 0.1 3.4 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORZ03330.1 - 9.2e-16 58.8 0.4 4.4e-15 56.5 0.2 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ03330.1 - 9e-13 47.7 0.0 2.8e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ03330.1 - 2.4e-05 24.2 0.4 5.1e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORZ03330.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 ORZ03330.1 - 0.025 14.3 7.3 0.082 12.6 7.3 1.9 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus GST_N_3 PF13417.6 ORZ03331.1 - 7e-19 68.0 0.1 1.1e-18 67.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORZ03331.1 - 1.9e-14 53.7 0.1 4.3e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORZ03331.1 - 8e-13 48.5 0.1 1.8e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 ORZ03331.1 - 2e-09 37.9 0.0 2.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORZ03331.1 - 2e-08 34.1 0.0 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORZ03331.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORZ03331.1 - 0.00017 21.7 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 ORZ03331.1 - 0.00028 21.0 0.0 0.00052 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin PilN PF05137.13 ORZ03331.1 - 0.0056 16.8 0.0 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 Fimbrial assembly protein (PilN) Muskelin_N PF06588.11 ORZ03332.1 - 1.9e-71 240.1 0.1 3.4e-71 239.3 0.1 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_6 PF13964.6 ORZ03332.1 - 2.3e-17 62.6 2.9 0.0051 17.1 0.1 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 ORZ03332.1 - 4.2e-17 62.0 9.6 1.4e-05 25.2 0.1 7.3 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 ORZ03332.1 - 1.9e-13 50.2 9.1 0.00029 20.8 0.0 5.8 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORZ03332.1 - 3.4e-11 42.9 8.4 0.011 15.7 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 ORZ03332.1 - 3.6e-09 36.0 4.7 0.0043 16.6 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 ORZ03332.1 - 1.8e-07 30.9 4.9 0.057 13.4 0.0 6.2 6 0 0 6 6 6 2 Kelch motif F5_F8_type_C PF00754.25 ORZ03332.1 - 0.00073 19.7 0.0 0.0024 18.0 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain GDPD PF03009.17 ORZ03333.1 - 3.5e-31 108.9 0.1 5.4e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Cation_ATPase_C PF00689.21 ORZ03334.1 - 1.5e-45 155.1 9.6 1.5e-45 155.1 9.6 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORZ03334.1 - 4.1e-34 117.7 0.0 4.1e-34 117.7 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORZ03334.1 - 7.6e-19 67.6 0.0 1.5e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORZ03334.1 - 1.6e-17 64.5 0.9 1.4e-16 61.4 0.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORZ03334.1 - 4.2e-09 36.0 0.1 1.3e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORZ03334.1 - 5e-06 26.4 0.4 0.0019 18.0 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.6 ORZ03335.1 - 9.4e-13 48.4 2.8 1.2e-06 28.9 1.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 ORZ03335.1 - 2.9e-11 42.0 6.5 0.0018 17.7 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ORZ03335.1 - 5.4e-11 42.2 7.1 8.1e-09 35.2 1.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORZ03335.1 - 2.6e-10 39.4 4.8 0.0015 18.3 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 ORZ03335.1 - 0.00012 21.4 2.0 0.015 14.8 0.1 3.5 4 0 0 4 4 4 1 EF hand EF-hand_11 PF08976.11 ORZ03335.1 - 0.0021 18.9 0.2 0.02 15.7 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 ORZ03335.1 - 0.012 15.6 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Syntaxin PF00804.25 ORZ03335.1 - 0.032 13.9 0.4 0.51 10.0 0.1 2.0 2 0 0 2 2 2 0 Syntaxin Dockerin_1 PF00404.18 ORZ03335.1 - 0.047 13.9 0.0 0.9 9.8 0.0 2.5 2 1 0 2 2 2 0 Dockerin type I domain MFS_1 PF07690.16 ORZ03336.1 - 2.8e-48 164.6 30.9 3.8e-43 147.8 17.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ03336.1 - 9.7e-10 37.9 11.8 9.7e-10 37.9 11.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORZ03336.1 - 1.6e-08 33.4 4.2 2.8e-08 32.7 4.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 ORZ03336.1 - 0.00047 19.2 2.6 0.0012 17.8 0.1 2.3 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM ATG22 PF11700.8 ORZ03336.1 - 0.0077 14.9 11.0 0.0089 14.7 1.3 3.4 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like Sulfate_transp PF00916.20 ORZ03338.1 - 1.5e-105 353.1 22.2 1.9e-105 352.7 22.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORZ03338.1 - 1.1e-10 41.2 0.0 2.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORZ03338.1 - 7.3e-06 26.2 0.1 1.7e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORZ03338.1 - 0.00014 22.2 4.1 0.00014 22.2 4.1 3.2 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily Fe-ADH PF00465.19 ORZ03339.1 - 2.7e-107 358.8 0.0 3.1e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORZ03339.1 - 3.4e-14 53.2 0.0 3.4e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase IucA_IucC PF04183.12 ORZ03340.1 - 5.6e-21 75.2 0.0 1.3e-20 74.0 0.0 1.6 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 ORZ03340.1 - 8.2e-13 49.1 0.1 2.6e-12 47.4 0.1 1.9 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter p450 PF00067.22 ORZ03341.1 - 1.4e-78 264.7 0.0 1.8e-78 264.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SAM_Ste50p PF09235.10 ORZ03341.1 - 0.079 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Exotox-A_cataly PF09009.10 ORZ03342.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A catalytic SWIB PF02201.18 ORZ03343.1 - 4.2e-27 93.8 0.0 6.6e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain MMADHC PF10229.9 ORZ03344.1 - 9.2e-19 68.2 0.0 1.2e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein ETF PF01012.21 ORZ03345.1 - 3.1e-50 170.6 2.2 5e-50 169.9 2.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain WD40 PF00400.32 ORZ03345.1 - 1.4e-06 28.9 11.1 0.18 12.7 0.9 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF_A PF03178.15 ORZ03345.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 CPSF A subunit region AMP-binding PF00501.28 ORZ03346.1 - 6.8e-96 321.4 0.0 8.3e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ03346.1 - 2.5e-23 82.8 0.0 5.6e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORZ03346.1 - 6.9e-20 70.7 3.3 3.3e-19 68.5 0.6 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus zf-trcl PF13451.6 ORZ03346.1 - 0.0086 15.9 0.0 0.055 13.4 0.0 2.2 2 0 0 2 2 2 1 Probable zinc-ribbon domain Aminotran_1_2 PF00155.21 ORZ03347.1 - 2.4e-57 194.8 0.0 2.9e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORZ03347.1 - 0.0018 17.3 0.0 0.0058 15.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORZ03347.1 - 0.0055 16.0 0.0 0.012 14.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORZ03347.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Myb_Cef PF11831.8 ORZ03348.1 - 9.1e-39 133.4 2.5 9.1e-39 133.4 2.5 4.1 3 2 2 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.6 ORZ03348.1 - 1.5e-21 76.4 6.4 5.9e-14 52.1 3.4 3.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORZ03348.1 - 4e-21 74.9 11.4 2.5e-11 43.6 1.2 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain MbeD_MobD PF04899.12 ORZ03348.1 - 0.22 11.6 5.1 0.13 12.4 1.0 2.5 2 0 0 2 2 2 0 MbeD/MobD like Rap1_C PF11626.8 ORZ03348.1 - 0.45 10.6 3.9 1.5 8.9 0.1 3.5 4 1 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CDP-OH_P_transf PF01066.21 ORZ03350.1 - 3.5e-17 62.9 0.1 3.5e-17 62.9 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF21 PF01595.20 ORZ03350.1 - 0.0034 17.1 1.0 0.0034 17.1 1.0 2.1 2 1 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Citrate_bind PF16114.5 ORZ03351.1 - 3.6e-90 300.2 0.1 7.1e-90 299.2 0.1 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Ligase_CoA PF00549.19 ORZ03351.1 - 2.1e-17 63.4 0.1 4e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.21 ORZ03351.1 - 1.3e-16 60.6 0.0 2.4e-15 56.5 0.0 2.6 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain CoA_binding PF02629.19 ORZ03351.1 - 3.2e-13 50.2 0.0 7.1e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 ORZ03351.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ORZ03351.1 - 1.3e-06 28.2 0.0 8.1e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain SseB PF07179.12 ORZ03351.1 - 0.083 13.2 0.0 1 9.6 0.1 2.6 3 0 0 3 3 3 0 SseB protein N-terminal domain zf-C2H2 PF00096.26 ORZ03352.1 - 1.1e-15 57.1 42.8 9.4e-05 22.7 3.7 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03352.1 - 8.1e-10 38.7 38.4 0.006 17.3 2.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORZ03352.1 - 2.7e-07 30.7 37.2 0.00013 22.2 4.0 5.6 5 0 0 5 5 5 2 Zinc-finger double domain RPAP2_Rtr1 PF04181.13 ORZ03352.1 - 0.015 15.6 0.1 18 5.7 1.0 3.6 2 2 1 3 3 3 0 Rtr1/RPAP2 family FOXP-CC PF16159.5 ORZ03352.1 - 0.027 15.1 6.5 0.027 15.1 6.5 5.0 4 1 0 4 4 4 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 ORZ03352.1 - 0.042 13.8 4.8 9 6.4 0.1 4.3 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger Porph_ging PF09697.10 ORZ03352.1 - 0.67 10.5 7.0 3.9 8.1 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) MAJIN PF15077.6 ORZ03352.1 - 0.97 9.2 11.2 0.2 11.4 2.2 2.3 2 0 0 2 2 2 0 Membrane-anchored junction protein zf-C2H2_aberr PF17017.5 ORZ03352.1 - 1 9.5 16.9 1.6 8.9 1.4 3.8 2 2 1 4 4 4 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORZ03352.1 - 1.9 8.3 25.2 0.75 9.6 1.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Roughex PF06020.11 ORZ03352.1 - 2.5 7.1 12.2 0.1 11.6 1.7 2.3 2 0 0 2 2 2 0 Drosophila roughex protein RSB_motif PF16294.5 ORZ03352.1 - 5.7 7.3 14.5 1.1 9.6 2.7 2.4 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif DUF719 PF05334.13 ORZ03352.1 - 6.3 6.9 10.3 13 5.9 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) zf-C2H2_9 PF16293.5 ORZ03352.1 - 7.8 6.4 8.7 32 4.5 0.2 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 ORZ03352.1 - 8.2 6.8 17.8 7.6 6.9 2.8 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ADH_N PF08240.12 ORZ03353.1 - 2.7e-27 94.8 5.2 5.8e-27 93.7 5.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ03353.1 - 1.4e-21 76.8 0.0 2.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORZ03353.1 - 1.3e-05 24.6 0.1 2.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORZ03353.1 - 4.6e-05 24.5 0.0 6.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORZ03353.1 - 8.1e-05 22.1 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 ORZ03353.1 - 0.03 13.1 0.0 0.058 12.1 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase GFO_IDH_MocA PF01408.22 ORZ03353.1 - 0.18 12.6 0.0 0.51 11.2 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Met_10 PF02475.16 ORZ03354.1 - 2.7e-69 232.9 0.0 4.1e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 ORZ03354.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.15 ORZ03354.1 - 0.0016 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_11 PF08241.12 ORZ03354.1 - 0.0069 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORZ03354.1 - 0.01 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 ORZ03354.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_23 PF13489.6 ORZ03354.1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PI3_PI4_kinase PF00454.27 ORZ03355.1 - 3.5e-55 187.5 0.0 9.7e-55 186.1 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 ORZ03355.1 - 4.7e-36 124.4 0.6 8.6e-35 120.2 0.6 2.9 1 1 0 1 1 1 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 ORZ03355.1 - 8.1e-11 41.5 0.1 1.8e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 ORZ03355.1 - 0.0024 18.0 0.4 1.3 9.4 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat FRB_dom PF08771.11 ORZ03355.1 - 0.16 12.4 8.3 6.7 7.2 3.8 4.3 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Dynactin PF12455.8 ORZ03356.1 - 5.4e-92 308.1 11.9 5.4e-92 308.1 11.9 3.5 3 1 1 4 4 4 1 Dynein associated protein SART-1 PF03343.13 ORZ03357.1 - 1.8e-153 512.5 75.8 2e-153 512.3 75.8 1.0 1 0 0 1 1 1 1 SART-1 family DUF3439 PF11921.8 ORZ03357.1 - 1.5 8.8 3.9 3.1 7.8 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S24 PF00717.23 ORZ03358.1 - 1e-10 41.4 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Complex1_49kDa PF00346.19 ORZ03359.1 - 4.3e-121 403.1 0.0 5.9e-121 402.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 ORZ03359.1 - 0.0027 16.7 0.0 0.0062 15.5 0.0 1.5 1 1 0 1 1 1 1 Nickel-dependent hydrogenase WD40 PF00400.32 ORZ03360.1 - 3.4e-45 151.1 21.0 1.3e-08 35.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03360.1 - 6.5e-19 68.0 5.8 0.00062 20.0 0.2 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ03360.1 - 1.8e-08 34.5 3.0 0.00034 20.5 0.0 3.0 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORZ03360.1 - 0.0011 18.3 0.0 0.4 9.9 0.0 2.7 1 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 ORZ03360.1 - 0.0074 15.3 0.4 3 6.7 0.0 2.6 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 ORZ03360.1 - 0.03 13.4 0.0 3.8 6.5 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 ORZ03360.1 - 0.11 11.2 0.5 7.6 5.2 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like CENP-F_leu_zip PF10473.9 ORZ03361.1 - 0.0015 18.6 4.4 0.0022 18.0 4.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 ORZ03361.1 - 0.009 16.1 11.4 0.009 16.1 11.4 2.9 1 1 1 3 3 3 1 Basic region leucine zipper Nup54 PF13874.6 ORZ03361.1 - 0.012 15.7 8.9 1.4 9.0 9.6 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.12 ORZ03361.1 - 0.02 15.0 4.4 0.02 15.0 4.4 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 ORZ03361.1 - 0.05 13.7 20.4 0.051 13.7 17.4 2.4 1 1 1 2 2 2 0 bZIP transcription factor TRAF_BIRC3_bd PF16673.5 ORZ03361.1 - 1.4 8.8 8.5 0.26 11.1 3.6 2.3 1 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain M PF02370.16 ORZ03361.1 - 2.4 9.0 5.0 30 5.7 0.9 3.2 3 1 0 3 3 3 0 M protein repeat DUF1765 PF08578.10 ORZ03362.1 - 4.1e-26 91.9 3.9 8e-26 91.0 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SEP PF08059.13 ORZ03363.1 - 1e-28 99.7 0.1 2.9e-28 98.2 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 ORZ03363.1 - 5.9e-19 68.1 0.1 9.4e-19 67.4 0.1 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 ORZ03363.1 - 1.4e-11 44.1 0.1 5.5e-11 42.1 0.1 2.0 2 0 0 2 2 2 1 UBA-like domain DUF3810 PF12725.7 ORZ03365.1 - 0.001 18.5 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3810) DUF5392 PF17370.2 ORZ03365.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5392) HTH_32 PF13565.6 ORZ03366.1 - 0.0052 17.4 0.3 0.12 13.0 0.1 2.7 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 ORZ03366.1 - 0.0073 16.3 0.1 0.029 14.4 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix DUF1804 PF08822.11 ORZ03366.1 - 0.038 14.0 0.2 0.068 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) HTH_28 PF13518.6 ORZ03366.1 - 0.11 12.7 0.2 0.33 11.1 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 ORZ03367.1 - 7e-13 48.5 1.7 0.0013 18.8 0.0 3.4 3 0 0 3 3 3 3 Helix-turn-helix domain HTH_23 PF13384.6 ORZ03367.1 - 1.7e-12 46.7 0.5 0.003 17.3 0.1 4.1 4 0 0 4 4 4 3 Homeodomain-like domain HTH_Tnp_1 PF01527.20 ORZ03367.1 - 2.4e-09 37.4 3.7 0.03 14.6 0.3 3.8 1 1 2 3 3 3 3 Transposase HTH_29 PF13551.6 ORZ03367.1 - 6.4e-06 26.1 1.6 0.08 13.0 0.2 3.0 1 1 1 2 2 2 2 Winged helix-turn helix HTH_psq PF05225.16 ORZ03367.1 - 0.00038 20.1 0.3 0.0025 17.5 0.1 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_32 PF13565.6 ORZ03367.1 - 0.0008 20.0 2.5 0.86 10.3 0.0 3.4 3 1 1 4 4 3 2 Homeodomain-like domain HTH_17 PF12728.7 ORZ03367.1 - 0.00081 19.5 0.2 1.1 9.4 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_1 PF00126.27 ORZ03367.1 - 0.0013 18.7 1.0 1.2 9.1 0.0 3.1 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4_2 PF08281.12 ORZ03367.1 - 0.02 14.6 0.0 6.2 6.6 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 DNA_pol_lambd_f PF10391.9 ORZ03367.1 - 0.027 14.3 1.9 0.63 9.9 0.1 3.2 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda HTH_3 PF01381.22 ORZ03367.1 - 0.028 14.5 0.0 0.67 10.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix LZ_Tnp_IS481 PF13011.6 ORZ03367.1 - 0.033 14.7 3.7 0.73 10.4 0.2 3.8 2 1 1 3 3 3 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 ORZ03367.1 - 0.038 13.4 1.7 0.24 10.8 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DUF746 PF05344.11 ORZ03367.1 - 0.047 13.5 0.1 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) DUF1804 PF08822.11 ORZ03367.1 - 0.13 12.3 10.0 0.71 9.8 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1804) PSS PF03034.15 ORZ03368.1 - 3e-111 371.5 11.8 4.4e-111 371.0 11.8 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase ABC_membrane PF00664.23 ORZ03369.1 - 3.4e-62 210.6 25.7 4.9e-40 137.9 6.7 3.2 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORZ03369.1 - 1.3e-52 177.9 0.0 1.1e-29 103.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORZ03369.1 - 1.4e-09 37.7 1.2 0.0049 16.3 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 ORZ03369.1 - 2.3e-06 26.9 0.0 0.019 14.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 ORZ03369.1 - 2.5e-06 28.1 0.1 0.0058 17.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ORZ03369.1 - 5.9e-06 26.6 1.6 0.13 12.6 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORZ03369.1 - 6.7e-06 25.8 0.1 0.022 14.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 ORZ03369.1 - 2.2e-05 24.7 0.3 0.066 13.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORZ03369.1 - 2.9e-05 23.7 0.4 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ORZ03369.1 - 5.1e-05 23.1 0.0 1.5 8.5 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF87 PF01935.17 ORZ03369.1 - 9.2e-05 22.6 1.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 ORZ03369.1 - 0.00013 22.4 0.2 0.68 10.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORZ03369.1 - 0.00027 20.9 0.0 0.087 12.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORZ03369.1 - 0.00057 20.0 0.3 0.42 10.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase EMC3_TMCO1 PF01956.16 ORZ03369.1 - 0.00067 19.4 1.2 0.002 17.9 1.2 1.8 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like AAA_18 PF13238.6 ORZ03369.1 - 0.00096 19.7 0.0 1 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORZ03369.1 - 0.0032 16.7 0.5 0.53 9.4 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain ATP_bind_1 PF03029.17 ORZ03369.1 - 0.0034 17.2 1.1 1.7 8.4 0.3 2.9 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 ORZ03369.1 - 0.0066 16.2 0.7 2.2 8.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORZ03369.1 - 0.0075 16.0 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORZ03369.1 - 0.012 16.1 0.1 1.9 8.9 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 ORZ03369.1 - 0.012 15.5 3.0 7 6.4 0.1 4.0 4 1 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORZ03369.1 - 0.012 15.1 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2512 PF10710.9 ORZ03369.1 - 0.013 15.1 1.2 0.047 13.4 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) cobW PF02492.19 ORZ03369.1 - 0.014 15.0 2.1 0.16 11.6 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 ORZ03369.1 - 0.018 14.4 0.0 4.9 6.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 ORZ03369.1 - 0.029 13.9 0.5 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 ORZ03369.1 - 0.03 13.6 0.0 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 ORZ03369.1 - 0.033 14.6 0.2 12 6.4 0.1 2.6 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 ORZ03369.1 - 0.033 14.2 0.2 13 5.8 0.0 3.2 2 1 0 3 3 3 0 AAA domain MeaB PF03308.16 ORZ03369.1 - 0.035 13.1 0.0 0.48 9.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 ORZ03369.1 - 0.035 14.2 0.0 15 5.7 0.0 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.23 ORZ03369.1 - 0.038 14.0 0.9 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 ORZ03369.1 - 0.039 14.2 0.2 14 5.9 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORZ03369.1 - 0.047 13.4 0.4 5.6 6.6 0.5 2.3 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 ORZ03369.1 - 0.051 12.8 0.2 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Septin SRP54 PF00448.22 ORZ03369.1 - 0.072 12.7 0.4 6.5 6.3 0.1 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 ORZ03369.1 - 0.088 12.7 4.2 3.4 7.6 0.2 3.0 3 0 0 3 3 3 0 NACHT domain MobB PF03205.14 ORZ03369.1 - 0.088 12.7 0.3 9.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 ORZ03369.1 - 0.088 11.7 0.3 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 ORZ03369.1 - 0.16 12.0 0.3 30 4.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 ORZ03369.1 - 0.16 11.9 0.8 15 5.4 0.2 2.6 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 ORZ03369.1 - 0.21 11.3 0.2 8.2 6.2 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 ORZ03369.1 - 0.28 10.9 1.2 7.1 6.3 0.2 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 ORZ03369.1 - 0.28 10.9 0.7 8.9 6.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RseC_MucC PF04246.12 ORZ03369.1 - 3 7.8 9.4 0.14 12.1 0.3 3.3 3 0 0 3 3 1 0 Positive regulator of sigma(E), RseC/MucC OrfB_Zn_ribbon PF07282.11 ORZ03370.1 - 0.003 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORZ03371.1 - 2.8e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain MFS_2 PF13347.6 ORZ03374.1 - 2.7e-11 42.7 4.2 2.7e-11 42.7 4.2 2.8 4 0 0 4 4 4 1 MFS/sugar transport protein MFS_1_like PF12832.7 ORZ03374.1 - 2.4e-05 23.4 0.0 0.0002 20.3 0.0 2.3 1 1 0 1 1 1 1 MFS_1 like family AAA_12 PF13087.6 ORZ03375.1 - 4.9e-56 189.5 0.1 7.9e-56 188.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORZ03375.1 - 4e-48 164.5 0.4 1.6e-47 162.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORZ03375.1 - 3.1e-13 49.9 0.1 6e-12 45.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ORZ03375.1 - 2.1e-09 37.5 0.1 0.0025 17.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ORZ03375.1 - 3.2e-07 30.8 0.1 1.3e-06 28.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORZ03375.1 - 3.5e-07 29.8 0.2 4.1e-06 26.3 0.2 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 ORZ03375.1 - 5.9e-06 26.4 0.2 8.1e-05 22.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORZ03375.1 - 1.9e-05 25.1 0.2 6.1e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORZ03375.1 - 5.4e-05 23.5 0.9 0.00078 19.7 0.7 2.9 2 1 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 ORZ03375.1 - 6.9e-05 22.9 0.3 0.002 18.1 0.0 2.6 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea PIF1 PF05970.14 ORZ03375.1 - 0.00011 21.6 0.0 0.029 13.6 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase AAA PF00004.29 ORZ03375.1 - 0.00018 22.0 1.0 0.006 17.0 0.2 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORZ03375.1 - 0.0002 21.0 3.3 0.013 15.1 0.0 3.5 2 1 2 4 4 4 1 AAA domain 4HB_MCP_1 PF12729.7 ORZ03375.1 - 0.00093 18.8 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction UvrD-helicase PF00580.21 ORZ03375.1 - 0.0012 18.4 0.5 0.053 13.0 0.0 2.8 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 ORZ03375.1 - 0.0018 17.4 0.1 0.0053 15.9 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein CbiA PF01656.23 ORZ03375.1 - 0.002 18.2 0.9 0.006 16.6 0.1 2.2 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 ORZ03375.1 - 0.0023 17.7 0.2 0.0081 15.9 0.0 2.0 2 0 0 2 2 1 1 IstB-like ATP binding protein PhoH PF02562.16 ORZ03375.1 - 0.0045 16.5 0.0 0.039 13.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 ORZ03375.1 - 0.0052 16.5 0.0 0.021 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORZ03375.1 - 0.0083 16.2 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zot PF05707.12 ORZ03375.1 - 0.0096 15.6 0.3 0.54 9.9 0.0 2.5 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.9 ORZ03375.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF853 PF05872.12 ORZ03375.1 - 0.023 13.3 0.0 0.086 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_31 PF13614.6 ORZ03375.1 - 0.025 14.5 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 ORZ03375.1 - 0.033 13.1 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TK PF00265.18 ORZ03375.1 - 0.039 13.8 0.1 0.77 9.6 0.0 2.5 3 0 0 3 3 2 0 Thymidine kinase Lipase_GDSL_2 PF13472.6 ORZ03375.1 - 0.045 14.1 0.1 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SRP54 PF00448.22 ORZ03375.1 - 0.061 12.9 1.4 0.86 9.2 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NACHT PF05729.12 ORZ03375.1 - 0.071 13.0 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_7 PF12775.7 ORZ03375.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 ORZ03375.1 - 0.092 13.3 0.0 0.33 11.5 0.0 2.2 1 1 0 1 1 1 0 ABC transporter ATPase PF06745.13 ORZ03375.1 - 0.097 12.0 0.2 0.46 9.8 0.2 2.0 1 1 0 1 1 1 0 KaiC AAA_33 PF13671.6 ORZ03375.1 - 0.1 12.7 0.1 0.3 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain UvrD_C PF13361.6 ORZ03375.1 - 0.13 11.7 0.2 1.5 8.2 0.0 2.4 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 ORZ03375.1 - 0.13 12.1 0.1 2.9 7.8 0.0 2.9 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain RNA_helicase PF00910.22 ORZ03375.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PFK PF00365.20 ORZ03376.1 - 2.1e-195 647.4 2.3 4.2e-109 364.3 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 ORZ03376.1 - 0.028 14.0 0.1 0.098 12.3 0.1 1.9 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 ORZ03376.1 - 0.12 11.6 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 ATP-NAD kinase UVR PF02151.19 ORZ03376.1 - 0.31 10.8 1.4 0.71 9.7 1.4 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif HECT PF00632.25 ORZ03377.1 - 5.4e-86 288.9 0.0 1e-85 288.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ima1_N PF09779.9 ORZ03377.1 - 0.068 14.0 1.2 0.15 12.9 1.2 1.5 1 0 0 1 1 1 0 Ima1 N-terminal domain F-box PF00646.33 ORZ03378.1 - 1.2e-06 28.2 0.4 5.7e-06 26.1 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORZ03378.1 - 0.00027 20.8 0.8 0.00092 19.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like Leo1 PF04004.13 ORZ03379.1 - 3e-35 121.5 0.4 3e-35 121.5 0.4 2.8 3 0 0 3 3 3 1 Leo1-like protein DDHD PF02862.17 ORZ03379.1 - 0.24 11.6 9.9 1.9 8.6 5.8 2.3 2 0 0 2 2 2 0 DDHD domain TMEM18 PF14770.6 ORZ03380.1 - 5.2e-35 120.0 5.8 6.5e-35 119.7 5.8 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF2985 PF11204.8 ORZ03380.1 - 0.051 13.7 3.9 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) PI31_Prot_N PF11566.8 ORZ03381.1 - 2e-37 128.5 0.0 2.4e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 ORZ03381.1 - 6.9e-12 46.4 15.0 6.9e-12 46.4 15.0 3.2 2 1 1 3 3 3 1 PI31 proteasome regulator Pro_isomerase PF00160.21 ORZ03383.1 - 6.5e-52 176.0 0.0 7.6e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_4 PF12799.7 ORZ03384.1 - 0.076 13.5 2.5 2.8 8.5 1.0 3.1 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Myb_DNA-binding PF00249.31 ORZ03385.1 - 6.1e-27 93.6 0.1 4.3e-09 36.4 0.1 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORZ03385.1 - 6.6e-09 35.9 7.4 0.0029 17.8 0.9 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORZ03385.1 - 4.5e-06 26.5 17.8 4.1e-05 23.4 0.5 4.2 4 0 0 4 4 4 2 Myb DNA-binding like Mit_KHE1 PF10173.9 ORZ03385.1 - 2.6 8.1 6.3 2.1 8.4 2.6 2.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Pkinase PF00069.25 ORZ03386.1 - 2.9e-71 239.9 0.0 4.2e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03386.1 - 7.2e-31 107.4 0.0 4.2e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03386.1 - 1.9e-08 34.0 0.8 0.01 15.2 0.0 3.2 2 1 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 ORZ03386.1 - 0.0011 17.8 0.0 0.0031 16.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORZ03386.1 - 0.041 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORZ03386.1 - 0.041 13.8 0.0 0.2 11.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Polysacc_deac_1 PF01522.21 ORZ03387.1 - 9.5e-25 86.9 0.0 2.2e-24 85.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase TackOD1 PF18551.1 ORZ03388.1 - 0.0031 17.2 6.8 0.39 10.4 0.3 2.2 2 0 0 2 2 2 2 Thaumarchaeal output domain 1 DZR PF12773.7 ORZ03388.1 - 0.01 15.9 0.6 0.01 15.9 0.6 3.2 2 1 0 2 2 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 ORZ03388.1 - 0.014 15.3 0.2 0.014 15.3 0.2 2.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 HypA PF01155.19 ORZ03388.1 - 0.047 13.7 0.8 0.047 13.7 0.8 3.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 ORZ03388.1 - 0.051 14.3 7.7 2.9 8.7 7.8 2.8 1 1 1 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 ORZ03388.1 - 0.08 13.1 1.1 0.08 13.1 1.1 3.5 3 1 0 3 3 3 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 ORZ03388.1 - 0.084 13.0 8.2 0.23 11.7 0.8 3.2 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_9 PF14369.6 ORZ03388.1 - 0.094 13.0 2.4 0.094 13.0 2.4 3.2 3 0 0 3 3 3 0 zinc-ribbon zinc-ribbons_6 PF07191.12 ORZ03388.1 - 0.93 9.5 10.4 0.32 11.0 0.4 3.0 2 1 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 ORZ03388.1 - 4.3 6.9 15.8 0.98 8.9 1.2 4.8 4 1 0 4 4 4 0 zinc-ribbon domain zf-ACC PF17848.1 ORZ03388.1 - 5.1 7.3 10.6 11 6.2 0.1 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain DUF900 PF05990.12 ORZ03389.1 - 0.0006 19.4 0.0 0.00096 18.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 ORZ03389.1 - 0.0092 15.8 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF4536 PF15055.6 ORZ03389.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) TPMT PF05724.11 ORZ03391.1 - 3.3e-39 134.8 0.0 4.6e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 ORZ03391.1 - 2.9e-14 53.5 0.0 4.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03391.1 - 1.1e-11 45.2 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ03391.1 - 9.1e-09 36.0 0.0 1.4e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03391.1 - 2e-07 30.9 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ03391.1 - 5.7e-07 29.5 0.0 6.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORZ03391.1 - 0.0051 16.2 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 ORZ03391.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 ORZ03391.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pet100 PF09803.9 ORZ03392.1 - 8.2e-24 83.9 0.3 9.9e-24 83.7 0.3 1.0 1 0 0 1 1 1 1 Pet100 tRNA_m1G_MT PF01746.21 ORZ03392.1 - 0.11 12.2 0.6 0.15 11.7 0.6 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase PHD PF00628.29 ORZ03393.1 - 2.2e-10 40.3 7.0 2.2e-10 40.3 7.0 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 ORZ03393.1 - 0.00045 19.7 5.3 0.00091 18.7 5.3 1.6 1 0 0 1 1 1 1 PHD-finger T_hemolysin PF12261.8 ORZ03395.1 - 0.021 14.6 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Thermostable hemolysin Pigment_DH PF06324.11 ORZ03396.1 - 0.098 12.8 0.2 37 4.7 0.0 3.2 3 0 0 3 3 3 0 Pigment-dispersing hormone (PDH) PLDc_2 PF13091.6 ORZ03397.1 - 1.3e-15 57.4 0.0 2.1e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORZ03397.1 - 0.00011 22.3 0.5 0.18 12.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif ZU5 PF00791.20 ORZ03397.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 ZU5 domain NOC3p PF07540.11 ORZ03398.1 - 8.5e-26 90.3 0.5 8.5e-26 90.3 0.5 2.6 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 ORZ03398.1 - 3.2e-24 85.9 1.2 3.2e-24 85.9 1.2 2.7 3 0 0 3 3 3 1 CBF/Mak21 family Histone PF00125.24 ORZ03398.1 - 0.019 15.3 0.7 0.019 15.3 0.7 4.0 4 1 0 4 4 4 0 Core histone H2A/H2B/H3/H4 RhoGEF PF00621.20 ORZ03399.1 - 1e-36 126.9 1.0 2.3e-36 125.8 1.0 1.6 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 ORZ03399.1 - 1e-26 93.0 0.0 2.1e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 ORZ03399.1 - 2.8e-22 79.3 0.7 7e-22 78.0 0.7 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 ORZ03399.1 - 2.2e-14 53.2 0.0 5.3e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 ORZ03399.1 - 8.9e-05 23.0 1.0 0.0003 21.3 0.4 2.1 2 0 0 2 2 2 1 PH domain AA_permease_2 PF13520.6 ORZ03400.1 - 2.8e-70 237.3 35.5 3.4e-70 237.0 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORZ03400.1 - 1.2e-19 70.3 27.1 1.8e-19 69.7 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 ORZ03402.1 - 2.7e-09 37.0 11.0 4.5e-09 36.3 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DRIM PF07539.12 ORZ03402.1 - 0.0071 14.7 1.2 0.01 14.2 1.2 1.1 1 0 0 1 1 1 1 Down-regulated in metastasis Phage_int_SAM_6 PF18644.1 ORZ03403.1 - 0.0023 17.9 1.0 0.009 16.0 0.0 2.1 1 1 0 2 2 2 1 Phage integrase SAM-like domain RPW8 PF05659.11 ORZ03403.1 - 0.17 11.5 3.3 0.22 11.2 0.8 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2570 PF10828.8 ORZ03403.1 - 0.96 9.3 5.1 0.5 10.2 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Syntaxin_2 PF14523.6 ORZ03403.1 - 1 9.7 9.7 2.4 8.6 2.8 2.6 1 1 1 2 2 2 0 Syntaxin-like protein ALMT PF11744.8 ORZ03403.1 - 1.7 7.4 7.2 3.2 6.5 7.3 1.4 1 1 1 2 2 2 0 Aluminium activated malate transporter CCDC-167 PF15188.6 ORZ03403.1 - 2.3 8.6 6.9 0.81 10.1 1.5 2.5 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF745 PF05335.13 ORZ03403.1 - 6.2 6.5 11.1 14 5.3 1.0 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF745) Peptidase_M16_M PF16187.5 ORZ03405.1 - 2.8e-97 325.4 5.6 4.3e-97 324.8 5.6 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORZ03405.1 - 1e-40 139.1 0.0 4.1e-40 137.2 0.0 2.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORZ03405.1 - 6.7e-31 107.7 2.2 2.6e-20 73.2 0.1 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain UCH PF00443.29 ORZ03405.1 - 0.15 11.5 1.0 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase NUC153 PF08159.12 ORZ03405.1 - 1.2 9.0 3.8 13 5.7 0.0 2.6 2 0 0 2 2 2 0 NUC153 domain Skp1_POZ PF03931.15 ORZ03406.1 - 9.7e-12 44.9 0.1 2e-11 43.9 0.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF1687 PF07955.11 ORZ03407.1 - 2.3e-13 50.7 0.0 4e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 ORZ03407.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 ArsC family PAH PF02671.21 ORZ03407.1 - 0.089 13.0 2.1 0.12 12.5 2.1 1.6 1 1 0 1 1 1 0 Paired amphipathic helix repeat TRAP_alpha PF03896.16 ORZ03408.1 - 3.4e-14 52.7 0.0 7.6e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2151 PF10221.9 ORZ03409.1 - 0.024 13.2 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF1896 PF08989.10 ORZ03411.1 - 0.13 12.4 0.2 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) FXMRP1_C_core PF12235.8 ORZ03411.1 - 0.7 10.5 11.5 2.9 8.5 10.9 2.4 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal MatE PF01554.18 ORZ03413.1 - 1.1e-43 148.7 34.3 4.3e-24 85.0 14.1 2.4 2 0 0 2 2 2 2 MatE Integrase_H2C2 PF17921.1 ORZ03414.1 - 1.8e-13 50.4 0.0 1.8e-13 50.4 0.0 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 ORZ03414.1 - 0.029 14.6 1.5 0.036 14.3 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger MatE PF01554.18 ORZ03415.1 - 7.5e-54 181.7 35.2 4.6e-35 120.7 12.5 3.1 4 0 0 4 4 4 2 MatE Bac_export_2 PF01312.19 ORZ03415.1 - 3.8 6.6 7.2 9.4 5.3 7.2 1.7 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family UPRTase PF14681.6 ORZ03416.1 - 2.1e-65 220.1 0.0 3.5e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 ORZ03416.1 - 1.5e-62 210.8 0.1 2.1e-62 210.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 ORZ03416.1 - 1.4e-06 28.3 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 ORZ03416.1 - 0.00055 20.5 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORZ03416.1 - 0.014 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ORZ03416.1 - 0.024 15.1 0.1 9.7 6.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain CoaE PF01121.20 ORZ03416.1 - 0.026 14.2 0.3 0.14 11.8 0.3 2.0 1 1 0 1 1 1 0 Dephospho-CoA kinase Cytidylate_kin PF02224.18 ORZ03416.1 - 0.085 12.6 0.2 7.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase Pribosyltran PF00156.27 ORZ03416.1 - 0.16 11.5 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain EMP24_GP25L PF01105.24 ORZ03417.1 - 9.6e-45 152.8 0.0 1.2e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF846 PF05832.12 ORZ03417.1 - 0.022 14.8 1.2 0.069 13.2 0.2 2.0 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) Pro_isomerase PF00160.21 ORZ03418.1 - 3.7e-49 167.0 0.1 3.7e-49 167.0 0.1 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GAGA_bind PF06217.12 ORZ03418.1 - 0.006 16.9 5.5 0.0075 16.6 5.5 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family SLC12 PF03522.15 ORZ03418.1 - 0.0097 15.0 4.8 0.013 14.5 4.8 1.2 1 0 0 1 1 1 1 Solute carrier family 12 Med19 PF10278.9 ORZ03418.1 - 0.03 14.3 24.1 0.058 13.3 24.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TLP-20 PF06088.11 ORZ03418.1 - 0.098 12.5 4.2 0.15 12.0 4.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Coilin_N PF15862.5 ORZ03418.1 - 0.17 11.7 15.1 0.31 10.9 15.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 ORZ03418.1 - 0.19 10.4 11.2 0.26 10.0 11.2 1.2 1 0 0 1 1 1 0 Presenilin YqfQ PF14181.6 ORZ03418.1 - 0.26 11.5 10.3 0.42 10.8 10.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.14 ORZ03418.1 - 0.32 9.2 17.8 0.39 8.9 17.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 ORZ03418.1 - 0.51 10.3 3.8 0.64 10.0 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 ORZ03418.1 - 0.65 8.9 3.8 0.91 8.4 3.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PI3K_1B_p101 PF10486.9 ORZ03418.1 - 0.8 7.4 16.0 1.1 7.0 16.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 ORZ03418.1 - 1.7 7.4 19.0 2.2 7.0 19.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 ORZ03418.1 - 2.2 8.0 12.8 3.3 7.5 12.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MAP65_ASE1 PF03999.12 ORZ03418.1 - 2.4 6.7 19.4 3.5 6.2 19.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LAP1C PF05609.12 ORZ03418.1 - 5 6.1 14.2 6.6 5.7 14.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 ORZ03418.1 - 5.4 4.0 9.5 6.6 3.7 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 ORZ03418.1 - 6.5 5.2 13.6 7.9 4.9 13.6 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 ORZ03418.1 - 7.1 5.7 10.6 11 5.1 10.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter VMA21 PF09446.10 ORZ03419.1 - 2e-11 43.8 5.9 3e-11 43.3 5.9 1.3 1 0 0 1 1 1 1 VMA21-like domain RseC_MucC PF04246.12 ORZ03419.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Endonuclease_NS PF01223.23 ORZ03420.1 - 1.2e-62 211.7 0.0 1.4e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MFS_1 PF07690.16 ORZ03421.1 - 1.8e-19 69.9 34.1 1.8e-19 69.9 34.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 ORZ03421.1 - 0.02 13.2 4.9 0.81 7.9 4.6 2.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BTP PF05232.12 ORZ03421.1 - 0.35 10.9 0.0 0.35 10.9 0.0 3.8 4 0 0 4 4 4 0 Chlorhexidine efflux transporter USP8_dimer PF08969.11 ORZ03422.1 - 2.9e-17 62.9 0.6 5.2e-17 62.1 0.6 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain JAB PF01398.21 ORZ03422.1 - 1.3e-15 57.4 0.0 2.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 ORZ03422.1 - 4.5e-05 23.2 0.0 9.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TPR_8 PF13181.6 ORZ03422.1 - 1.2 9.5 4.9 0.24 11.7 0.7 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GWT1 PF06423.12 ORZ03423.1 - 3.1e-10 40.3 0.3 1e-09 38.7 0.1 1.9 2 0 0 2 2 2 1 GWT1 DUF3810 PF12725.7 ORZ03423.1 - 0.35 10.2 1.0 1.3 8.4 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Transket_pyr PF02779.24 ORZ03426.1 - 1.7e-46 158.1 0.2 3.5e-46 157.1 0.1 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORZ03426.1 - 2.9e-34 117.6 0.0 8.8e-34 116.1 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain CBFB_NFYA PF02045.15 ORZ03427.1 - 1.1e-27 96.4 7.1 1.1e-27 96.4 7.1 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Rib PF08428.10 ORZ03428.1 - 1.1 9.4 4.8 1.3 9.0 1.3 2.3 2 0 0 2 2 2 0 Rib/alpha-like repeat Q_salvage PF10343.9 ORZ03429.1 - 3.8e-30 105.4 0.0 2.8e-29 102.6 0.0 1.9 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family CBFD_NFYB_HMF PF00808.23 ORZ03430.1 - 1.7e-18 66.6 0.4 5.6e-18 65.0 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORZ03430.1 - 5.1e-09 36.6 6.5 6.3e-09 36.3 0.2 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 U3_assoc_6 PF08640.11 ORZ03431.1 - 4.4e-27 94.0 10.4 9.6e-27 92.9 6.9 2.9 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 ORZ03431.1 - 1.6e-07 30.8 6.7 0.065 12.4 0.4 4.8 3 2 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 ORZ03431.1 - 1.2e-06 28.8 2.7 0.76 10.8 0.1 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 ORZ03431.1 - 0.0015 17.6 4.0 0.097 11.7 0.9 2.5 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 ORZ03431.1 - 0.0074 16.6 0.7 68 4.2 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 ORZ03431.1 - 0.026 14.5 0.6 0.5 10.3 0.0 2.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Endonuc-MspI PF09208.10 ORZ03431.1 - 0.033 13.6 0.4 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease MspI TPR_2 PF07719.17 ORZ03431.1 - 0.052 13.7 3.5 63 4.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PMEI PF04043.15 ORZ03431.1 - 0.06 13.7 0.9 3.1 8.1 0.0 2.8 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Zn_clus PF00172.18 ORZ03432.1 - 9.6e-09 35.2 12.9 1.7e-08 34.4 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 ORZ03432.1 - 0.015 14.9 8.2 0.015 14.9 8.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 ORZ03432.1 - 0.66 10.0 8.9 1.8 8.5 1.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Hydrolase_like PF13242.6 ORZ03433.1 - 1e-11 44.7 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORZ03433.1 - 0.0016 18.8 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 ORZ03434.1 - 7.5e-49 166.0 0.4 8.3e-49 165.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 ORZ03436.1 - 2e-49 167.9 0.2 2.3e-49 167.7 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.23 ORZ03437.1 - 1.2e-65 221.6 1.0 1.8e-65 220.9 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 ORZ03437.1 - 1.5e-21 76.1 5.2 3.5e-14 52.4 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 ORZ03437.1 - 6.6e-19 68.3 0.0 1.7e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 ORZ03437.1 - 4.4e-18 65.5 0.3 4.4e-18 65.5 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 ORZ03437.1 - 4.5e-08 33.3 0.0 1.5e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 ORZ03437.1 - 9.9e-08 32.3 0.2 9.9e-08 32.3 0.2 5.5 4 1 1 5 5 4 1 Chromodomain helicase DNA-binding domain 1 HDA2-3 PF11496.8 ORZ03437.1 - 5e-06 25.9 0.2 1.2e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 ORZ03437.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 ORZ03437.1 - 0.002 18.2 0.2 0.0098 16.1 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain CDH1_2_SANT_HL1 PF18375.1 ORZ03437.1 - 0.0065 17.1 2.9 0.012 16.3 0.2 3.0 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 ORZ03437.1 - 0.0072 16.3 0.1 0.14 12.2 0.0 3.0 2 0 0 2 2 2 1 SLIDE DnaJ PF00226.31 ORZ03438.1 - 3.6e-21 75.0 5.8 3.6e-21 75.0 5.8 2.9 3 0 0 3 3 3 1 DnaJ domain TPR_9 PF13371.6 ORZ03438.1 - 2.1e-19 69.4 6.8 0.00019 21.5 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ03438.1 - 2.7e-17 61.8 4.5 4.5e-05 23.1 0.1 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ03438.1 - 1.9e-16 60.4 6.1 8.7e-06 26.3 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ03438.1 - 8.1e-14 50.5 11.7 0.033 14.3 0.0 6.7 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ03438.1 - 1.2e-13 51.3 11.8 0.00016 22.1 0.4 5.3 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ03438.1 - 2.1e-12 46.7 11.9 0.03 15.1 0.3 6.5 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ03438.1 - 2.7e-12 45.9 9.2 0.0034 17.5 0.2 6.9 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ03438.1 - 3.5e-11 42.6 1.0 1.2e-05 24.9 0.1 4.4 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 ORZ03438.1 - 2.2e-10 40.2 1.0 0.0003 21.0 0.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORZ03438.1 - 1.9e-09 37.5 7.8 0.0004 20.8 0.2 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ03438.1 - 1.8e-05 24.9 3.1 0.44 10.8 0.1 4.8 3 2 2 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 ORZ03438.1 - 0.00016 21.6 3.5 1.1 9.4 0.3 4.3 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 ORZ03438.1 - 0.004 17.4 6.6 5.2 7.4 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORZ03438.1 - 0.0058 16.9 12.1 0.039 14.3 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat YfiO PF13525.6 ORZ03438.1 - 0.0079 15.9 3.9 0.064 13.0 0.5 3.0 3 1 0 3 3 2 1 Outer membrane lipoprotein TPR_7 PF13176.6 ORZ03438.1 - 0.0096 15.9 3.3 3.8 7.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 ORZ03438.1 - 0.012 15.4 0.3 0.012 15.4 0.3 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain YqaH PF17448.2 ORZ03438.1 - 0.013 15.8 2.2 0.063 13.6 0.0 3.1 3 1 0 3 3 2 0 Uncharacterized YqaH-like BTAD PF03704.17 ORZ03438.1 - 0.021 15.3 4.8 27 5.2 0.1 4.1 2 1 1 4 4 4 0 Bacterial transcriptional activator domain DUF4810 PF16068.5 ORZ03438.1 - 0.26 11.9 1.6 2.1 9.0 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) Alkyl_sulf_dimr PF14863.6 ORZ03438.1 - 0.61 10.5 8.7 2 8.9 0.2 4.0 4 1 1 5 5 4 0 Alkyl sulfatase dimerisation DUF357 PF04010.13 ORZ03438.1 - 1.1 9.4 0.0 1.1 9.4 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF357) CotJB PF12652.7 ORZ03438.1 - 2.1 8.6 4.8 1.1 9.6 0.3 2.8 2 1 1 3 3 2 0 CotJB protein RPN7 PF10602.9 ORZ03438.1 - 3.1 7.5 10.8 0.33 10.6 0.1 4.1 4 2 0 4 4 4 0 26S proteasome subunit RPN7 DUF2408 PF10303.9 ORZ03438.1 - 5.8 7.5 6.5 2.8 8.5 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) TPR_4 PF07721.14 ORZ03438.1 - 6 7.8 12.2 3.3 8.6 0.3 4.7 6 0 0 6 6 3 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 ORZ03438.1 - 6.5 7.5 12.8 1.5 9.5 0.3 4.2 3 2 0 4 4 4 0 Cytochrome b562 Pkinase PF00069.25 ORZ03439.1 - 4.8e-69 232.6 0.0 1.3e-68 231.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03439.1 - 1.7e-39 135.7 0.0 2.9e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03439.1 - 0.00062 19.2 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORZ03439.1 - 0.0015 17.4 0.2 0.0055 15.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORZ03439.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2779 PF11074.8 ORZ03439.1 - 0.85 10.1 3.0 1.8 9.1 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function(DUF2779) Glyco_hydro_18 PF00704.28 ORZ03440.1 - 8.7e-18 65.1 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Syntaxin-6_N PF09177.11 ORZ03441.1 - 2.5e-28 98.5 3.8 2.5e-28 98.5 3.8 1.9 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 ORZ03441.1 - 1.9e-08 34.2 2.4 2.4e-07 30.6 0.8 2.8 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 ORZ03441.1 - 0.0014 18.4 1.6 0.0019 17.9 1.6 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 DASH_Duo1 PF08651.10 ORZ03441.1 - 0.0025 17.6 6.6 0.02 14.6 0.1 4.2 3 2 3 6 6 6 1 DASH complex subunit Duo1 Atg14 PF10186.9 ORZ03441.1 - 0.013 14.6 3.4 0.019 14.0 3.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 ORZ03441.1 - 0.054 11.4 4.1 0.072 11.0 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2207 PF09972.9 ORZ03441.1 - 0.1 11.4 0.6 2.2 7.0 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Exonuc_VII_L PF02601.15 ORZ03441.1 - 0.14 11.7 2.9 0.2 11.2 2.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 ORZ03441.1 - 0.18 11.5 3.5 0.51 10.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Sec34 PF04136.15 ORZ03441.1 - 0.2 11.6 5.5 0.19 11.6 0.8 2.6 2 1 1 3 3 3 0 Sec34-like family Herpes_US9 PF06072.11 ORZ03441.1 - 0.21 11.5 1.0 0.46 10.4 1.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 FAM76 PF16046.5 ORZ03441.1 - 0.67 9.3 3.5 0.49 9.7 1.8 1.5 1 1 0 2 2 2 0 FAM76 protein CorA PF01544.18 ORZ03441.1 - 0.84 8.9 12.2 0.033 13.5 2.6 2.7 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Sec2p PF06428.11 ORZ03441.1 - 4.7 7.3 12.1 2.5 8.1 1.9 3.7 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p Laminin_II PF06009.12 ORZ03441.1 - 8.3 6.4 7.6 2 8.4 0.4 2.7 2 1 0 3 3 3 0 Laminin Domain II HIP1_clath_bdg PF16515.5 ORZ03441.1 - 9.9 6.8 14.4 0.68 10.6 2.6 3.1 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CUE PF02845.16 ORZ03442.1 - 4.6e-09 35.8 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 CUE domain Hexokinase_2 PF03727.16 ORZ03443.1 - 2.2e-58 197.5 0.0 3.2e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORZ03443.1 - 3.7e-47 160.8 0.0 5.8e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF1543 PF07566.12 ORZ03443.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) HA2 PF04408.23 ORZ03444.1 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORZ03444.1 - 2.4e-15 56.9 0.0 1.1e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ORZ03444.1 - 1.6e-13 50.8 0.0 6.1e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ORZ03444.1 - 2.3e-09 37.3 0.2 4.4e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORZ03444.1 - 3.4e-05 24.1 0.1 7.7e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORZ03444.1 - 0.0035 17.7 0.2 0.0067 16.8 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORZ03444.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 ORZ03444.1 - 0.019 15.0 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORZ03444.1 - 0.025 13.6 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 ORZ03444.1 - 0.037 13.7 0.1 0.068 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORZ03444.1 - 0.041 13.3 0.1 0.45 9.9 0.1 2.6 3 0 0 3 3 3 0 PhoH-like protein Herpes_ori_bp PF02399.15 ORZ03444.1 - 0.07 11.2 0.1 0.11 10.6 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein FtsK_SpoIIIE PF01580.18 ORZ03444.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Flavi_DEAD PF07652.14 ORZ03444.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 ORZ03444.1 - 0.15 12.1 0.0 1.3 9.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORZ03444.1 - 0.16 12.5 0.6 3.2 8.3 0.2 2.3 1 1 1 2 2 2 0 ABC transporter DUF2075 PF09848.9 ORZ03444.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DASH_Dad4 PF08650.10 ORZ03445.1 - 2.7e-22 78.5 4.4 3.5e-22 78.1 4.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 ORZ03445.1 - 0.00057 20.0 0.5 0.00084 19.5 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 4HB_MCP_1 PF12729.7 ORZ03445.1 - 0.0042 16.7 2.1 0.0045 16.5 2.1 1.1 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction DASH_Dad2 PF08654.10 ORZ03445.1 - 0.011 16.1 3.3 0.013 15.9 3.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad2 Mce4_CUP1 PF11887.8 ORZ03445.1 - 0.033 13.7 0.6 0.041 13.3 0.6 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative ChpXY PF10216.9 ORZ03445.1 - 0.083 12.0 0.1 0.095 11.8 0.1 1.1 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) CH PF00307.31 ORZ03446.1 - 5.3e-22 78.1 0.0 8.4e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 ORZ03446.1 - 5.9e-05 22.6 1.4 9.9e-05 21.9 1.4 1.3 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 ORZ03446.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain Pkinase PF00069.25 ORZ03447.1 - 1.8e-20 73.4 0.0 4.3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 ORZ03447.1 - 2.4e-14 52.2 3.6 0.0017 18.5 0.2 6.7 6 0 0 6 6 6 4 HEAT repeat WD40 PF00400.32 ORZ03447.1 - 5.3e-14 52.4 1.7 2.4e-06 28.2 0.8 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 ORZ03447.1 - 6.4e-10 39.3 0.1 0.0002 21.7 0.1 4.2 2 2 3 5 5 5 3 HEAT repeats Pkinase_Tyr PF07714.17 ORZ03447.1 - 2e-05 24.0 0.0 4.4e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 ORZ03447.1 - 0.0036 17.4 7.5 2.1 8.4 0.0 4.1 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORZ03447.1 - 0.0078 16.7 0.3 0.0078 16.7 0.3 4.3 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 ORZ03447.1 - 0.01 16.0 1.7 2.7 8.2 0.1 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 ORZ03447.1 - 0.037 13.6 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 Tti2 family Pkinase PF00069.25 ORZ03448.1 - 4.8e-18 65.5 0.0 7.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03448.1 - 1.5e-12 47.3 0.0 5.5e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HATPase_c PF02518.26 ORZ03449.1 - 9.4e-33 113.1 0.1 2.5e-32 111.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORZ03449.1 - 4.1e-20 72.0 0.1 6.6e-19 68.1 0.0 2.9 3 0 0 3 3 3 1 Response regulator receiver domain AAA_16 PF13191.6 ORZ03449.1 - 1.7e-16 61.1 0.0 1.1e-15 58.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 ORZ03449.1 - 4.3e-16 58.7 0.0 1.8e-15 56.7 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ORZ03449.1 - 3.5e-12 46.8 0.0 6.3e-11 42.7 0.0 2.7 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.25 ORZ03449.1 - 1.6e-10 40.8 0.0 3.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 ORZ03449.1 - 5.4e-09 36.8 0.1 2.2e-07 31.6 0.0 2.9 2 0 0 2 2 2 1 GAF domain NB-ARC PF00931.22 ORZ03449.1 - 3.5e-06 26.4 0.3 0.00024 20.4 0.3 2.7 1 1 0 1 1 1 1 NB-ARC domain Pkinase_Tyr PF07714.17 ORZ03449.1 - 0.00045 19.6 0.0 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase GAF_3 PF13492.6 ORZ03449.1 - 0.0054 17.1 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 GAF domain ABC_tran PF00005.27 ORZ03449.1 - 0.018 15.6 0.0 0.056 14.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ORZ03449.1 - 0.031 14.5 0.1 0.16 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain Chs7 PF12271.8 ORZ03450.1 - 1.7e-105 352.6 19.4 1.9e-105 352.3 19.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2754 PF10953.8 ORZ03450.1 - 1.3 9.3 5.1 1.1 9.6 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) SET PF00856.28 ORZ03451.1 - 1.8e-20 74.0 0.5 9.8e-20 71.6 0.5 2.1 1 1 0 1 1 1 1 SET domain AWS PF17907.1 ORZ03451.1 - 4.6e-08 33.0 2.7 4.6e-08 33.0 2.7 2.4 3 0 0 3 3 3 1 AWS domain DEAD_2 PF06733.15 ORZ03452.1 - 9.7e-52 175.1 0.9 1.2e-51 174.8 0.1 1.6 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 ORZ03452.1 - 3.7e-50 170.3 1.7 2.8e-45 154.4 0.6 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 ORZ03452.1 - 2.1e-46 158.2 0.0 4.7e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 ORZ03452.1 - 5.8e-05 23.2 0.0 0.0039 17.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORZ03452.1 - 0.0017 18.1 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 ORZ03452.1 - 0.011 15.3 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 ORZ03452.1 - 0.04 14.2 0.0 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain YtxC PF08812.11 ORZ03452.1 - 0.063 12.9 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 YtxC-like family SNF2_N PF00176.23 ORZ03452.1 - 0.19 10.4 0.0 15 4.2 0.0 2.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain KCH PF16944.5 ORZ03453.1 - 2.5e-76 256.8 12.3 3e-76 256.5 12.3 1.1 1 0 0 1 1 1 1 Fungal potassium channel Tetrabrachion PF11401.8 ORZ03453.1 - 0.032 14.2 0.3 0.064 13.3 0.3 1.4 1 0 0 1 1 1 0 Tetrabrachion HTH_AsnC-type PF13404.6 ORZ03453.1 - 0.052 13.4 0.2 0.096 12.5 0.2 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Alg6_Alg8 PF03155.15 ORZ03455.1 - 1.4e-140 469.5 28.9 1.8e-140 469.1 28.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family bZIP_1 PF00170.21 ORZ03456.1 - 9.9e-11 41.6 9.7 9.9e-11 41.6 9.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORZ03456.1 - 2.1e-05 24.5 11.2 2.1e-05 24.5 11.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.8 ORZ03456.1 - 3.3e-05 24.2 1.7 3.3e-05 24.2 1.7 3.0 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 ORZ03456.1 - 0.007 16.7 4.7 0.007 16.7 4.7 3.0 2 1 0 2 2 2 1 Aft1 HRA domain ATF7IP_BD PF16788.5 ORZ03456.1 - 0.016 15.3 0.1 0.016 15.3 0.1 3.3 2 1 2 4 4 4 0 ATF-interacting protein binding domain bZIP_Maf PF03131.17 ORZ03456.1 - 0.044 14.3 11.5 0.074 13.6 10.6 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.18 ORZ03456.1 - 0.27 11.5 2.8 0.46 10.7 2.8 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper TFIIA PF03153.13 ORZ03456.1 - 3.3 7.6 14.7 4.1 7.3 14.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aa_trans PF01490.18 ORZ03458.1 - 4.8e-59 200.1 19.7 5.9e-59 199.8 19.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ectatomin PF06457.11 ORZ03458.1 - 0.11 12.4 1.2 0.25 11.3 1.2 1.6 1 0 0 1 1 1 0 Ectatomin SAPS PF04499.15 ORZ03459.1 - 2.9e-126 422.1 0.0 2.9e-126 422.1 0.0 2.8 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein EppA_BapA PF07268.11 ORZ03459.1 - 0.089 12.7 0.2 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) Hamartin PF04388.12 ORZ03459.1 - 0.12 11.0 3.4 0.19 10.4 3.4 1.3 1 0 0 1 1 1 0 Hamartin protein zf-HYPF PF07503.12 ORZ03459.1 - 0.42 10.4 1.4 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 HypF finger TPP1 PF10341.9 ORZ03461.1 - 0.0021 18.0 2.1 8 6.5 0.0 4.5 3 1 3 6 6 6 1 Shelterin complex subunit, TPP1/ACD ParBc PF02195.18 ORZ03461.1 - 0.27 11.6 2.9 6.9 7.0 0.2 3.6 2 1 2 4 4 4 0 ParB-like nuclease domain DUF3240 PF11582.8 ORZ03461.1 - 0.71 10.0 12.0 46 4.2 0.1 5.9 2 1 4 7 7 7 0 Protein of unknown function (DUF3240) MmcB-like PF06319.12 ORZ03461.1 - 2.4 7.8 10.6 9.1 5.9 0.3 3.8 3 1 2 5 5 5 0 DNA repair protein MmcB-like Mago-bind PF09282.10 ORZ03461.1 - 4.1 7.4 5.0 1.6e+02 2.3 0.1 4.7 4 0 0 4 4 4 0 Mago binding Pirin_C PF05726.13 ORZ03461.1 - 7 7.1 8.5 8.5 6.8 0.2 3.9 2 2 4 6 6 6 0 Pirin C-terminal cupin domain WRKY PF03106.15 ORZ03462.1 - 6.1e-11 42.4 2.7 1.4e-10 41.2 2.7 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.16 ORZ03462.1 - 0.029 14.5 0.4 0.051 13.7 0.4 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain Ribosomal_L13e PF01294.18 ORZ03463.1 - 3.4e-81 271.4 7.9 4.7e-81 270.9 7.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e G_glu_transpept PF01019.21 ORZ03464.1 - 4.6e-144 481.0 0.0 5.2e-144 480.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cofilin_ADF PF00241.20 ORZ03465.1 - 5.5e-20 71.4 0.0 6.2e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX7B PF05392.11 ORZ03466.1 - 0.049 13.3 0.9 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB DUF4293 PF14126.6 ORZ03466.1 - 0.052 13.8 3.5 0.043 14.1 1.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) AA_permease_2 PF13520.6 ORZ03466.1 - 0.075 11.9 12.6 0.022 13.6 8.6 1.8 1 1 1 2 2 2 0 Amino acid permease TMEM192 PF14802.6 ORZ03466.1 - 0.29 10.2 2.4 0.3 10.1 0.8 1.7 2 0 0 2 2 2 0 TMEM192 family DUF973 PF06157.11 ORZ03466.1 - 0.82 8.7 7.4 1.2 8.1 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF3169 PF11368.8 ORZ03466.1 - 2.2 7.7 9.3 0.36 10.3 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Ribosomal_L13 PF00572.18 ORZ03467.1 - 1.3e-10 41.6 0.0 1.1e-08 35.4 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 DUF4200 PF13863.6 ORZ03468.1 - 0.0093 16.4 4.7 0.016 15.6 3.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) HR1 PF02185.16 ORZ03468.1 - 0.025 14.7 3.4 0.047 13.8 3.4 1.5 1 0 0 1 1 1 0 Hr1 repeat DUF4315 PF14193.6 ORZ03468.1 - 0.15 12.1 3.2 0.34 10.9 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Erv26 PF04148.13 ORZ03469.1 - 1e-62 211.6 18.7 3.6e-62 209.8 18.7 1.7 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 ORZ03469.1 - 0.076 13.0 1.5 0.11 12.4 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) MAGE_N PF12440.8 ORZ03469.1 - 0.16 12.6 4.8 0.23 12.2 4.8 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Cytochrom_C_asm PF01578.20 ORZ03469.1 - 0.92 9.2 10.8 0.029 14.1 3.5 2.1 1 1 1 2 2 2 0 Cytochrome C assembly protein SRF-TF PF00319.18 ORZ03470.1 - 5.6e-22 77.0 0.1 8.4e-22 76.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.14 ORZ03470.1 - 1.4 7.1 9.1 2.4 6.4 9.1 1.3 1 1 0 1 1 1 0 CDC45-like protein Zip PF02535.22 ORZ03470.1 - 2.1 7.5 12.2 2.2 7.4 2.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter SpoU_methylase PF00588.19 ORZ03471.1 - 1.4e-12 48.0 0.0 3.6e-12 46.6 0.0 1.7 2 1 0 2 2 2 1 SpoU rRNA Methylase family p450 PF00067.22 ORZ03472.1 - 1.1e-82 278.3 0.0 1.2e-82 278.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 ORZ03473.1 - 1.7e-54 184.2 0.1 2.3e-54 183.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORZ03473.1 - 1.9e-15 56.2 0.1 3.7e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Zmiz1_N PF18028.1 ORZ03474.1 - 1.1e-06 28.8 0.1 2.5e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain BBS2_C PF14782.6 ORZ03474.1 - 0.12 11.1 4.1 0.2 10.4 4.1 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Enkurin PF13864.6 ORZ03474.1 - 0.46 10.9 7.2 4.7 7.7 6.1 2.6 2 0 0 2 2 2 0 Calmodulin-binding TFIIA PF03153.13 ORZ03474.1 - 4.8 7.1 56.4 0.96 9.4 35.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phage_GPO PF05929.11 ORZ03474.1 - 5.8 6.4 11.6 1 8.9 6.3 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-MIZ PF02891.20 ORZ03475.1 - 3.8e-07 29.7 0.6 5.7e-07 29.2 0.6 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger FSA_C PF10479.9 ORZ03475.1 - 0.21 9.7 1.9 0.26 9.4 1.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 ORZ03475.1 - 0.58 8.1 1.9 0.67 7.9 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 ORZ03475.1 - 5.4 5.1 8.6 6.4 4.8 8.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CytochromB561_N PF09786.9 ORZ03476.1 - 7.6e-05 21.9 0.3 0.0026 16.8 0.0 2.1 1 1 0 2 2 2 2 Cytochrome B561, N terminal DUF5596 PF18082.1 ORZ03477.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) PSP1 PF04468.12 ORZ03478.1 - 1.3e-30 105.5 5.0 2.3e-30 104.7 5.0 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DNA_mis_repair PF01119.19 ORZ03478.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain NUDIX PF00293.28 ORZ03479.1 - 0.0037 17.3 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FHA PF00498.26 ORZ03480.1 - 5.8e-17 61.8 0.0 1.1e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORZ03480.1 - 1.1e-07 32.1 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain AAA_23 PF13476.6 ORZ03480.1 - 0.076 13.5 10.5 0.13 12.7 10.5 1.3 1 0 0 1 1 1 0 AAA domain FAM199X PF15814.5 ORZ03481.1 - 0.49 9.4 3.9 0.75 8.8 3.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X SR-25 PF10500.9 ORZ03481.1 - 5.5 6.5 12.3 8.8 5.9 12.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4605 PF15378.6 ORZ03482.1 - 0.052 13.4 1.6 0.11 12.4 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) PHD PF00628.29 ORZ03483.1 - 1.4e-06 28.1 7.9 1.9e-06 27.6 7.9 1.2 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORZ03483.1 - 0.0098 15.4 4.4 0.0098 15.4 4.4 1.8 2 1 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 ORZ03483.1 - 0.15 12.4 4.3 0.22 11.8 4.4 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain Pkinase PF00069.25 ORZ03484.1 - 1.6e-67 227.7 0.0 2e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03484.1 - 3.9e-30 105.0 0.0 5.6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORZ03484.1 - 0.0012 18.2 1.5 0.0015 18.0 0.4 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORZ03484.1 - 0.0033 16.4 0.1 0.0056 15.7 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORZ03484.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Phage_sheath_1C PF17482.2 ORZ03484.1 - 0.043 13.8 0.2 0.14 12.1 0.2 1.9 1 1 0 1 1 1 0 Phage tail sheath C-terminal domain Pkinase_fungal PF17667.1 ORZ03484.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAS_9 PF13426.7 ORZ03485.1 - 8.4e-21 74.2 0.0 4.8e-15 55.7 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 ORZ03485.1 - 9.9e-21 73.8 0.1 1.7e-13 50.7 0.0 3.7 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 ORZ03485.1 - 1.4e-14 53.4 5.2 2.6e-14 52.5 5.2 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 ORZ03485.1 - 5.1e-12 46.0 0.0 4.1e-05 23.8 0.0 4.3 3 1 1 4 4 4 2 PAS fold PAS PF00989.25 ORZ03485.1 - 1.4e-09 38.0 0.0 5.1e-05 23.2 0.0 3.3 2 1 0 2 2 2 2 PAS fold PAS_11 PF14598.6 ORZ03485.1 - 7.2e-09 35.8 0.0 2e-07 31.1 0.0 2.7 2 0 0 2 2 2 1 PAS domain DUF4763 PF15960.5 ORZ03485.1 - 0.002 17.5 2.0 0.0039 16.5 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Flavoprotein PF02441.19 ORZ03486.1 - 1.4e-53 180.9 0.2 1.6e-53 180.7 0.2 1.0 1 0 0 1 1 1 1 Flavoprotein RINGv PF12906.7 ORZ03487.1 - 6.6e-11 42.2 7.2 6.6e-11 42.2 7.2 1.8 2 0 0 2 2 2 1 RING-variant domain DUF1616 PF07760.11 ORZ03487.1 - 0.015 14.7 0.2 0.025 14.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) TRP PF06011.12 ORZ03487.1 - 0.071 11.8 1.4 0.3 9.7 0.0 2.0 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel F-box-like PF12937.7 ORZ03488.1 - 4.7e-08 32.8 0.4 1.7e-07 31.0 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ03488.1 - 1.3e-05 24.9 0.0 1.3e-05 24.9 0.0 2.3 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 ORZ03488.1 - 0.0087 16.5 4.6 5.4 7.6 0.0 5.0 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORZ03488.1 - 0.083 13.0 7.7 13 6.2 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat TFIIA PF03153.13 ORZ03488.1 - 5.4 6.9 10.6 1.1 9.2 7.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORZ03488.1 - 6.3 6.3 11.6 11 5.6 11.6 1.2 1 0 0 1 1 1 0 Spt20 family NAD_binding_1 PF00175.21 ORZ03489.1 - 4.7e-28 98.0 0.0 7.4e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORZ03489.1 - 1.1e-14 54.5 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORZ03489.1 - 3.4e-08 33.7 0.0 1.4e-05 25.2 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Phage_TAC_6 PF09550.10 ORZ03489.1 - 0.21 12.1 0.6 2.4 8.6 0.0 2.6 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC DNA_RNApol_7kD PF03604.13 ORZ03490.1 - 6e-18 64.2 4.8 8.2e-18 63.8 4.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.18 ORZ03490.1 - 0.0018 18.1 1.5 0.72 9.8 0.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) DZR PF12773.7 ORZ03490.1 - 0.0018 18.2 0.8 0.0024 17.9 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn_ribbon_recom PF13408.6 ORZ03490.1 - 0.0072 16.8 2.0 0.097 13.2 0.3 2.1 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zinc_ribbon_10 PF10058.9 ORZ03490.1 - 0.0092 15.7 1.5 0.34 10.7 0.1 2.1 1 1 1 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 ORZ03490.1 - 0.0098 15.9 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MCM_OB PF17207.3 ORZ03490.1 - 0.01 15.7 0.7 0.011 15.6 0.7 1.1 1 0 0 1 1 1 1 MCM OB domain zf-trcl PF13451.6 ORZ03490.1 - 0.011 15.6 1.5 3.6 7.6 0.2 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain NinF PF05810.12 ORZ03490.1 - 0.011 15.5 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 NinF protein zinc-ribbon_6 PF10005.9 ORZ03490.1 - 0.018 15.7 0.2 0.024 15.3 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.8 ORZ03490.1 - 0.023 14.6 0.8 3 7.8 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) OrfB_Zn_ribbon PF07282.11 ORZ03490.1 - 0.024 14.6 0.3 0.029 14.3 0.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-dskA_traR PF01258.17 ORZ03490.1 - 0.042 13.8 3.2 0.74 9.8 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger UPF0547 PF10571.9 ORZ03490.1 - 0.043 13.9 2.1 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf_UBZ PF18439.1 ORZ03490.1 - 0.047 13.3 2.3 4 7.1 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 ORZ03490.1 - 0.054 13.6 4.2 0.28 11.3 4.0 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_6 PF14599.6 ORZ03490.1 - 0.062 13.3 2.6 4.5 7.4 0.2 2.1 1 1 1 2 2 2 0 Zinc-ribbon GFA PF04828.14 ORZ03490.1 - 0.066 13.6 1.1 3.4 8.1 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.12 ORZ03490.1 - 0.067 12.7 1.7 1.6 8.3 2.6 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zf-NADH-PPase PF09297.11 ORZ03490.1 - 0.071 12.8 3.7 0.28 10.9 3.7 1.9 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF951 PF06107.11 ORZ03490.1 - 0.084 12.8 0.7 0.084 12.8 0.7 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-Mss51 PF13824.6 ORZ03490.1 - 0.12 12.5 1.7 3.7 7.7 0.1 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Rubredoxin_2 PF18073.1 ORZ03490.1 - 0.13 12.0 4.7 4.6 7.0 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 ORZ03490.1 - 0.13 12.0 3.1 1.7 8.5 3.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 ORZ03490.1 - 0.16 12.1 2.9 11 6.2 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger IF-2B PF01008.17 ORZ03491.1 - 3.5e-64 216.7 0.1 4.9e-64 216.2 0.1 1.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family PBP1_TM PF14812.6 ORZ03491.1 - 0.18 12.2 1.6 0.33 11.3 1.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APG6 PF04111.12 ORZ03492.1 - 2.7e-75 252.2 0.1 2.7e-75 252.2 0.1 1.7 2 1 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 ORZ03492.1 - 4.6e-31 108.1 27.5 4.6e-31 108.1 27.5 2.1 3 0 0 3 3 3 1 Apg6 coiled-coil region BH3 PF15285.6 ORZ03492.1 - 7.6e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting Hemagglutinin PF00509.18 ORZ03492.1 - 0.079 11.3 5.5 0.077 11.4 4.4 1.5 1 1 0 1 1 1 0 Haemagglutinin HAUS-augmin3 PF14932.6 ORZ03492.1 - 0.11 12.0 16.9 0.34 10.5 16.9 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 LMBR1 PF04791.16 ORZ03492.1 - 0.52 9.1 4.0 0.73 8.7 4.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 ORZ03492.1 - 3.5 8.3 21.7 0.058 14.0 13.3 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mitoc_mL59 PF18126.1 ORZ03493.1 - 6.4e-15 55.6 6.1 2.6e-13 50.4 6.1 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 CR6_interact PF10147.9 ORZ03493.1 - 0.0017 18.1 2.7 0.0025 17.6 2.7 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RrnaAD PF00398.20 ORZ03494.1 - 8.4e-33 113.6 0.0 9.6e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NDUF_B4 PF07225.12 ORZ03495.1 - 0.0038 17.1 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) BHD_3 PF10405.9 ORZ03496.1 - 1.6e-21 76.5 0.0 1.6e-20 73.3 0.0 2.3 1 1 1 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 ORZ03496.1 - 4e-18 65.0 0.0 7.7e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 ORZ03496.1 - 1.6e-15 57.0 0.2 1.6e-15 57.0 0.2 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 ORZ03496.1 - 5.3e-13 49.7 1.2 5.3e-13 49.7 1.2 3.3 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 ORZ03496.1 - 0.00035 21.0 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sin_N PF04801.13 ORZ03496.1 - 0.11 11.6 3.3 0.08 12.2 0.9 1.9 2 0 0 2 2 2 0 Sin-like protein conserved region NPR3 PF03666.13 ORZ03496.1 - 0.65 8.7 8.6 0.99 8.1 8.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ASXH PF13919.6 ORZ03497.1 - 6.5e-06 26.2 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Asx homology domain AT_hook PF02178.19 ORZ03497.1 - 4.2 7.6 13.0 0.12 12.4 4.0 3.2 2 0 0 2 2 2 0 AT hook motif Usp PF00582.26 ORZ03499.1 - 6.4e-21 75.3 1.9 1.7e-20 74.0 0.0 2.4 2 1 0 2 2 2 1 Universal stress protein family Abhydrolase_3 PF07859.13 ORZ03500.1 - 4.2e-33 115.0 0.0 2.4e-32 112.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORZ03500.1 - 3.7e-13 49.1 0.0 5.6e-09 35.3 0.0 2.4 2 1 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 ORZ03500.1 - 0.0056 16.5 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 ORZ03500.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) STE PF02200.16 ORZ03501.1 - 0.00026 21.4 0.1 0.00044 20.6 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor EXOSC1 PF10447.9 ORZ03502.1 - 3.5e-17 63.0 3.3 1.3e-13 51.5 0.1 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 ORZ03502.1 - 9.2e-13 47.8 3.9 1.1e-12 47.6 1.0 2.4 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 ORZ03502.1 - 0.077 13.3 1.2 1 9.7 1.2 2.4 1 1 0 1 1 1 0 S1 RNA binding domain YABBY PF04690.13 ORZ03503.1 - 1.1e-09 39.1 1.9 1.2e-09 39.0 1.9 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 ORZ03503.1 - 1.1e-07 32.5 4.2 1.4e-07 32.1 4.2 1.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 ORZ03503.1 - 2.6e-06 27.8 0.8 4.1e-06 27.1 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ03503.1 - 6.6e-05 23.4 0.6 0.00011 22.7 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain MFS_1 PF07690.16 ORZ03504.1 - 1.7e-23 83.1 30.7 2e-21 76.3 30.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily YtpI PF14007.6 ORZ03504.1 - 0.08 13.1 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 YtpI-like protein FAD_binding_2 PF00890.24 ORZ03505.1 - 9.9e-42 143.5 2.1 9.9e-41 140.2 2.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORZ03505.1 - 4.7e-09 36.3 1.2 4.7e-09 36.3 1.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORZ03505.1 - 1e-08 35.0 0.4 1.4e-07 31.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORZ03505.1 - 7.7e-08 31.5 1.2 6.9e-05 21.7 0.2 3.1 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 ORZ03505.1 - 1.8e-07 30.7 0.2 8.8e-05 21.9 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORZ03505.1 - 6.6e-07 28.7 5.4 1.1e-05 24.8 0.2 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORZ03505.1 - 3.1e-05 23.4 0.2 0.00028 20.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORZ03505.1 - 0.00059 20.0 0.3 0.0024 18.0 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORZ03505.1 - 0.00075 18.5 0.2 0.0016 17.4 0.1 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 ORZ03505.1 - 0.0028 17.0 0.7 0.022 14.0 0.1 2.5 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 ORZ03505.1 - 0.0035 16.6 0.0 0.0035 16.6 0.0 1.9 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 ORZ03505.1 - 0.0052 15.9 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORZ03505.1 - 0.0091 16.5 1.8 0.17 12.5 0.1 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORZ03505.1 - 0.061 12.6 2.0 0.13 11.5 0.2 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Mcp5_PH PF12814.7 ORZ03506.1 - 3.8e-40 136.8 0.1 8.9e-40 135.6 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TolA_bind_tri PF16331.5 ORZ03506.1 - 0.00052 20.0 9.1 0.00052 20.0 9.1 4.5 4 0 0 4 4 4 1 TolA binding protein trimerisation PH PF00169.29 ORZ03506.1 - 0.001 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Scaffolding_pro PF11418.8 ORZ03506.1 - 2.8 8.6 11.7 13 6.4 0.4 3.3 1 1 2 3 3 3 0 Phi29 scaffolding protein Aldo_ket_red PF00248.21 ORZ03507.1 - 4.7e-51 173.7 0.1 2.6e-49 168.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PPR_2 PF13041.6 ORZ03508.1 - 3e-27 94.5 0.3 1.8e-07 31.3 0.2 6.9 5 2 2 7 7 7 5 PPR repeat family PPR_3 PF13812.6 ORZ03508.1 - 1.8e-24 85.6 0.1 9.2e-11 41.7 0.0 5.6 3 2 2 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 ORZ03508.1 - 2.4e-16 58.8 0.1 5.9e-07 29.3 0.0 7.2 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 ORZ03508.1 - 5.4e-16 58.6 0.5 9e-06 25.2 0.0 4.3 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORZ03508.1 - 5.1e-13 48.5 0.0 3e-07 30.0 0.1 5.4 5 0 0 5 5 5 2 PPR repeat TPR_MalT PF17874.1 ORZ03508.1 - 0.016 14.6 2.3 3.3 7.0 0.0 3.2 3 0 0 3 3 3 0 MalT-like TPR region Peptidase_A21 PF03566.13 ORZ03509.1 - 0.18 10.0 0.1 0.24 9.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase family A21 Baculo_11_kDa PF06143.11 ORZ03509.1 - 0.2 11.3 0.1 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family MoCF_biosynth PF00994.24 ORZ03510.1 - 1.2e-31 109.4 0.0 1.7e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain TPP_enzyme_N PF02776.18 ORZ03511.1 - 8e-32 110.2 0.0 2.7e-31 108.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORZ03511.1 - 5.7e-19 68.2 0.0 1.3e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORZ03511.1 - 3.6e-18 65.8 0.2 7.1e-18 64.8 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glucan_synthase PF02364.15 ORZ03511.1 - 0.0074 14.5 0.1 0.01 14.0 0.1 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component DUF362 PF04015.12 ORZ03511.1 - 0.052 13.8 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF362) Nup192 PF11894.8 ORZ03511.1 - 0.077 10.1 0.0 0.13 9.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 AA_permease PF00324.21 ORZ03512.1 - 3.5e-127 424.9 34.4 4.4e-127 424.6 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORZ03512.1 - 2e-47 162.0 37.8 2.4e-47 161.8 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease Snf7 PF03357.21 ORZ03513.1 - 1.6e-47 161.3 23.6 1.9e-47 161.0 23.6 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 ORZ03513.1 - 0.042 14.3 13.0 0.073 13.5 6.1 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Hydantoinase_B PF02538.14 ORZ03513.1 - 0.052 12.0 2.1 0.063 11.7 2.1 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase PRTP PF01366.18 ORZ03513.1 - 0.1 10.7 5.3 0.13 10.3 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF1319 PF07028.11 ORZ03513.1 - 0.4 10.9 8.5 0.11 12.7 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) WDCP PF15390.6 ORZ03513.1 - 0.41 9.0 5.0 0.52 8.6 5.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3926 PF13080.6 ORZ03513.1 - 1 9.3 4.3 25 4.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) PEP-utilisers_N PF05524.13 ORZ03513.1 - 1.6 8.9 9.9 0.55 10.4 4.4 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Csm2_III-A PF03750.13 ORZ03513.1 - 1.6 9.6 14.2 11 6.9 4.8 2.7 1 1 2 3 3 3 0 Csm2 Type III-A V_ATPase_I PF01496.19 ORZ03513.1 - 3.7 5.4 11.3 4.2 5.2 11.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNARE PF05739.19 ORZ03513.1 - 4.6 7.3 5.8 2.3 8.3 0.6 3.0 2 1 1 3 3 3 0 SNARE domain DUF848 PF05852.11 ORZ03513.1 - 7.5 6.7 16.0 1.1 9.3 10.1 2.3 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch PF05377.11 ORZ03513.1 - 8.9 6.8 13.6 6.7 7.2 0.1 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF1840 PF08895.11 ORZ03513.1 - 9.6 6.6 11.5 0.37 11.2 0.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) WD40 PF00400.32 ORZ03514.1 - 2.1e-10 41.0 17.5 0.0014 19.4 0.2 6.7 7 1 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 ORZ03514.1 - 0.073 11.7 0.1 2.2 6.8 0.1 2.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 UIM PF02809.20 ORZ03514.1 - 1.3 9.1 0.0 0.058 13.3 3.8 3.5 4 0 0 4 4 4 0 Ubiquitin interaction motif Ank_3 PF13606.6 ORZ03515.1 - 1.5e-09 37.3 0.0 0.00029 21.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORZ03515.1 - 8.8e-08 32.6 0.0 3.2e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORZ03515.1 - 0.00011 22.4 0.1 0.038 14.3 0.0 3.3 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 ORZ03515.1 - 0.0048 17.3 0.1 0.15 12.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORZ03515.1 - 0.0072 16.9 0.0 0.16 12.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DDRGK PF09756.9 ORZ03516.1 - 4.9e-08 32.8 25.4 4.9e-08 32.8 25.4 1.5 2 0 0 2 2 2 1 DDRGK domain HTH_Tnp_ISL3 PF13542.6 ORZ03516.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Hid1 PF12722.7 ORZ03516.1 - 0.19 9.8 7.1 0.21 9.7 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cupin_8 PF13621.6 ORZ03516.1 - 0.74 9.5 3.9 0.98 9.1 3.9 1.3 1 0 0 1 1 1 0 Cupin-like domain DUF99 PF01949.16 ORZ03516.1 - 1.4 8.3 5.6 0.31 10.4 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF99 DUF2828 PF11443.8 ORZ03516.1 - 1.9 6.5 12.2 2.4 6.1 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1283 PF06932.11 ORZ03516.1 - 1.9 8.7 22.0 0.12 12.6 4.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1283) DUF5401 PF17380.2 ORZ03516.1 - 2.1 6.3 34.7 2.6 6.0 34.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) WDCP PF15390.6 ORZ03516.1 - 2.2 6.6 7.0 2.3 6.5 7.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4407 PF14362.6 ORZ03516.1 - 2.5 7.4 15.6 3.4 6.9 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.6 ORZ03516.1 - 2.9 7.6 15.1 3.9 7.2 15.1 1.2 1 0 0 1 1 1 0 AAA domain SET PF00856.28 ORZ03516.1 - 3.4 8.0 5.9 4.8 7.5 5.9 1.3 1 1 0 1 1 1 0 SET domain RR_TM4-6 PF06459.12 ORZ03516.1 - 3.6 7.3 15.2 4.9 6.9 15.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 ORZ03516.1 - 6.8 6.7 18.9 8.7 6.3 18.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_S8 PF00410.19 ORZ03517.1 - 2.5e-23 82.4 0.0 3.6e-23 81.9 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein S8 LAGLIDADG_WhiA PF14527.6 ORZ03517.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Pescadillo_N PF06732.11 ORZ03518.1 - 9.4e-121 402.5 5.6 9.4e-121 402.5 5.6 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 ORZ03518.1 - 6.7e-08 32.8 0.0 2.3e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORZ03518.1 - 0.00025 21.4 0.6 0.004 17.5 0.0 3.0 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain NFRKB_winged PF14465.6 ORZ03518.1 - 0.03 14.5 0.1 0.16 12.2 0.0 2.3 3 0 0 3 3 3 0 NFRKB Winged Helix-like LIG3_BRCT PF16759.5 ORZ03518.1 - 0.03 14.6 0.0 0.14 12.5 0.0 2.2 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain Glyco_hydro_18 PF00704.28 ORZ03519.1 - 3.2e-87 293.2 0.0 3.7e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HSP90 PF00183.18 ORZ03520.1 - 7e-235 780.8 34.5 8.7e-235 780.5 34.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORZ03520.1 - 2.3e-15 57.1 0.1 5.3e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORZ03520.1 - 2.1e-09 37.3 0.1 2.1e-09 37.3 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box PF00505.19 ORZ03522.1 - 2.3e-13 50.3 0.3 4.7e-13 49.3 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box SR-25 PF10500.9 ORZ03522.1 - 6.5 6.3 11.1 1.5 8.3 1.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Carn_acyltransf PF00755.20 ORZ03523.1 - 3.8e-171 570.7 0.0 4.3e-171 570.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase UbiA PF01040.18 ORZ03523.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family SNARE PF05739.19 ORZ03524.1 - 1.1e-13 50.9 0.1 2.5e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 ORZ03524.1 - 0.00021 20.4 0.4 0.00058 19.0 0.4 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 ORZ03524.1 - 0.00095 18.9 1.6 0.00095 18.9 1.6 3.8 3 1 0 4 4 4 1 Syntaxin Troponin PF00992.20 ORZ03524.1 - 0.04 14.2 0.6 0.04 14.2 0.6 2.4 2 1 0 2 2 2 0 Troponin Syntaxin-18_N PF10496.9 ORZ03524.1 - 0.11 12.8 4.6 0.1 12.8 1.3 2.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF948 PF06103.11 ORZ03524.1 - 0.58 10.5 5.8 11 6.3 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 ORZ03524.1 - 0.76 10.3 12.8 1.2 9.7 3.5 2.9 2 2 0 2 2 2 0 Protein of unknown function DUF16 HemX PF04375.14 ORZ03524.1 - 0.76 9.0 10.9 0.35 10.1 3.7 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase NPV_P10 PF05531.12 ORZ03524.1 - 1.5 9.4 10.7 21 5.7 0.2 3.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 ORZ03524.1 - 1.5 9.3 10.0 0.4 11.1 0.3 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 ORZ03524.1 - 3.3 8.0 14.8 0.87 9.8 8.4 2.6 3 0 0 3 3 3 0 Flagellar FliJ protein SlyX PF04102.12 ORZ03524.1 - 6.5 7.4 14.3 0.52 11.0 1.5 3.8 2 2 1 3 3 3 0 SlyX TauD PF02668.16 ORZ03525.1 - 4.8e-58 197.1 1.4 4.8e-58 197.1 1.4 1.3 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family MINDY_DUB PF04424.13 ORZ03525.1 - 0.00012 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Glyco_hydro_28 PF00295.17 ORZ03526.1 - 1.3e-47 162.4 3.8 1.8e-47 162.0 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Haemadin PF09065.10 ORZ03526.1 - 1.5 8.7 6.9 0.14 12.0 0.8 2.5 3 0 0 3 3 3 0 Haemadin Methyltransf_11 PF08241.12 ORZ03527.1 - 3.5e-12 46.8 0.0 6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ03527.1 - 2.9e-11 43.9 0.0 5.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ03527.1 - 4.4e-07 29.5 0.0 6.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORZ03527.1 - 5.9e-06 26.2 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03527.1 - 9.4e-06 25.5 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ03527.1 - 0.00023 21.8 0.0 0.00038 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORZ03527.1 - 0.00082 19.3 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 ORZ03527.1 - 0.0032 16.1 0.0 0.0032 16.1 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 ORZ03527.1 - 0.066 12.7 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF2768 PF10966.8 ORZ03528.1 - 9.4 6.8 7.9 16 6.0 4.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2768) Glyco_hydro_28 PF00295.17 ORZ03529.1 - 6.5e-63 212.7 6.8 7.9e-63 212.5 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Rad51 PF08423.11 ORZ03530.1 - 1.4e-24 86.8 0.0 1.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 ORZ03530.1 - 6.9e-05 22.5 0.0 9.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORZ03530.1 - 0.0039 16.6 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 ORZ03530.1 - 0.0085 15.5 0.0 0.65 9.3 0.2 2.0 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain Holin_BlyA PF05102.12 ORZ03530.1 - 0.031 14.2 0.5 0.12 12.4 0.1 2.0 1 1 0 2 2 2 0 holin, BlyA family Pectinesterase PF01095.19 ORZ03531.1 - 3.9e-38 130.9 5.5 1.2e-37 129.3 5.5 1.6 1 1 0 1 1 1 1 Pectinesterase Pectinesterase PF01095.19 ORZ03532.1 - 1.5e-37 128.9 3.9 5.3e-37 127.1 3.9 1.7 1 1 0 1 1 1 1 Pectinesterase Chalcone PF02431.15 ORZ03532.1 - 0.1 12.0 0.3 0.63 9.4 0.2 2.0 2 0 0 2 2 2 0 Chalcone-flavanone isomerase Pkinase PF00069.25 ORZ03533.1 - 8.1e-53 179.5 0.0 1.4e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03533.1 - 1.3e-28 100.0 0.0 2.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORZ03533.1 - 1e-06 28.9 0.0 2.7e-06 27.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORZ03533.1 - 1.1e-05 25.0 0.0 7.3e-05 22.2 0.0 1.9 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORZ03533.1 - 0.0014 18.3 0.1 1 9.0 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORZ03533.1 - 0.049 12.6 0.1 0.083 11.8 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORZ03533.1 - 0.057 12.8 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORZ03533.1 - 0.059 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 ORZ03533.1 - 0.07 12.7 0.2 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Methyltransf_10 PF05971.12 ORZ03533.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase MFS_1 PF07690.16 ORZ03534.1 - 1e-41 143.1 49.2 1e-41 143.1 49.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ03534.1 - 7.2e-13 48.2 11.0 7.2e-13 48.2 11.0 3.1 3 1 0 4 4 4 1 Sugar (and other) transporter MmgE_PrpD PF03972.14 ORZ03534.1 - 0.14 10.6 0.6 0.3 9.6 0.0 1.6 2 0 0 2 2 2 0 MmgE/PrpD family Ipi1_N PF12333.8 ORZ03535.1 - 2.8e-21 76.0 1.8 2.8e-21 76.0 1.8 2.8 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation LEDGF PF11467.8 ORZ03535.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Cnd1 PF12717.7 ORZ03535.1 - 0.068 13.2 0.1 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORZ03535.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Transp_cyt_pur PF02133.15 ORZ03536.1 - 8.8e-34 117.0 38.1 1.3e-33 116.4 38.1 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pox_P21 PF05313.12 ORZ03536.1 - 0.022 14.4 1.5 0.044 13.3 1.5 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein dCMP_cyt_deam_1 PF00383.23 ORZ03537.1 - 4.3e-13 49.0 0.1 5.8e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORZ03537.1 - 5.2e-10 39.2 0.0 6.4e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 ORZ03537.1 - 0.062 13.4 0.3 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 tRNA-synt_1b PF00579.25 ORZ03538.1 - 6.7e-23 81.4 0.0 4e-22 78.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Elong-fact-P_C PF09285.11 ORZ03539.1 - 3.9e-14 52.1 0.2 3.5e-13 49.1 0.2 2.2 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 ORZ03539.1 - 3.2e-13 49.5 0.0 6.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 ORZ03539.1 - 1.5e-07 31.3 1.2 5.6e-07 29.5 0.4 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain DUF4857 PF16149.5 ORZ03539.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) H-kinase_dim PF02895.14 ORZ03540.1 - 0.05 14.0 0.3 0.07 13.5 0.3 1.2 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain EzrA PF06160.12 ORZ03540.1 - 0.055 11.6 0.0 0.067 11.4 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HBM PF16591.5 ORZ03540.1 - 0.064 12.7 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain Mito_carr PF00153.27 ORZ03541.1 - 3.6e-75 248.0 0.4 2e-26 91.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORZ03541.1 - 0.19 10.9 3.3 10 5.2 0.5 3.3 1 1 1 2 2 2 0 Gammaproteobacterial serine protease PTR2 PF00854.21 ORZ03542.1 - 2.3e-92 309.9 13.5 3.5e-92 309.3 13.5 1.2 1 0 0 1 1 1 1 POT family ABC_tran PF00005.27 ORZ03543.1 - 3.3e-39 134.5 0.1 8.2e-39 133.3 0.0 1.7 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 ORZ03543.1 - 4.3e-39 134.8 9.1 5.7e-39 134.4 9.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORZ03543.1 - 8.8e-05 22.0 0.1 0.0087 15.5 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORZ03543.1 - 0.00052 20.4 0.0 0.0015 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORZ03543.1 - 0.00061 20.2 0.0 0.027 14.9 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORZ03543.1 - 0.0019 18.5 0.1 0.015 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORZ03543.1 - 0.0025 17.8 0.0 0.069 13.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORZ03543.1 - 0.0082 16.2 0.0 0.08 13.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 ORZ03543.1 - 0.0089 15.8 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 ORZ03543.1 - 0.011 15.9 0.8 2.3 8.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain SbcCD_C PF13558.6 ORZ03543.1 - 0.018 15.3 0.2 0.24 11.6 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 ORZ03543.1 - 0.021 14.7 0.1 0.051 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORZ03543.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HRI1 PF16815.5 ORZ03543.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein HRI1 RsgA_GTPase PF03193.16 ORZ03543.1 - 0.035 14.0 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 ORZ03543.1 - 0.042 13.8 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 ORZ03543.1 - 0.047 14.2 0.0 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORZ03543.1 - 0.072 12.7 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORZ03543.1 - 0.11 13.0 0.0 0.87 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF1640 PF07798.11 ORZ03544.1 - 2.5e-35 122.1 2.6 4e-35 121.4 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Peptidase_M56 PF05569.11 ORZ03544.1 - 0.017 14.4 0.2 0.024 13.9 0.2 1.3 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF2062 PF09835.9 ORZ03544.1 - 0.041 13.8 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF3693 PF12472.8 ORZ03544.1 - 0.059 13.0 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Phage related protein PPP5 PF08321.12 ORZ03546.1 - 4.6e-31 107.0 2.1 4.6e-31 107.0 2.1 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 ORZ03546.1 - 1.5e-29 104.0 0.3 2.4e-29 103.3 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 ORZ03546.1 - 6.7e-14 50.8 5.9 0.001 19.0 1.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORZ03546.1 - 5.2e-11 41.9 12.0 5e-05 22.9 1.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ03546.1 - 1.8e-08 33.9 4.7 6.4e-05 22.5 0.2 3.2 1 1 2 3 3 3 2 TPR repeat TPR_9 PF13371.6 ORZ03546.1 - 3.9e-06 26.9 0.0 0.00014 21.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORZ03546.1 - 2.6e-05 24.8 1.4 0.0021 18.7 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORZ03546.1 - 7.6e-05 23.1 2.0 0.00061 20.3 0.9 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORZ03546.1 - 0.00015 21.9 3.1 0.13 12.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ03546.1 - 0.0003 20.7 3.3 0.081 13.2 0.7 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORZ03546.1 - 0.00075 19.7 3.9 0.0077 16.4 1.9 2.3 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ORZ03546.1 - 0.019 15.7 0.1 15 6.8 0.0 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat US6 PF17616.2 ORZ03546.1 - 0.059 13.3 0.1 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Viral unique short region 6 TPR_12 PF13424.6 ORZ03546.1 - 0.06 13.7 2.7 2 8.7 0.7 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat LOH1CR12 PF10158.9 ORZ03546.1 - 0.12 12.4 0.3 0.35 10.9 0.3 1.7 1 0 0 1 1 1 0 Tumour suppressor protein TPR_18 PF13512.6 ORZ03546.1 - 0.13 12.4 1.6 0.27 11.4 0.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORZ03546.1 - 0.14 12.5 0.2 0.14 12.5 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3759 PF12585.8 ORZ03548.1 - 3.9e-33 113.3 5.7 5e-33 113.0 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2939 PF11159.8 ORZ03548.1 - 0.039 14.4 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DEAD PF00270.29 ORZ03549.1 - 1.6e-37 129.0 0.0 4e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ03549.1 - 1.1e-21 77.2 0.1 7.2e-21 74.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 ORZ03549.1 - 0.0024 17.7 0.2 0.0042 16.9 0.2 1.4 1 0 0 1 1 1 1 HIT zinc finger LysM PF01476.20 ORZ03550.1 - 3.1e-13 49.5 0.0 9.4e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 LysM domain HTH_3 PF01381.22 ORZ03550.1 - 0.017 15.2 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix tRNA_anti-codon PF01336.25 ORZ03551.1 - 0.0026 17.7 0.1 0.0049 16.8 0.1 1.4 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain BOF PF04076.13 ORZ03551.1 - 0.088 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein tRNA_anti-like PF12869.7 ORZ03551.1 - 0.21 11.2 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA_anti-like NDK PF00334.19 ORZ03552.1 - 6.3e-38 129.8 0.0 7.4e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GDI PF00996.18 ORZ03553.1 - 1.2e-217 722.7 0.3 1.4e-217 722.4 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 ORZ03553.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SH3_14 PF18343.1 ORZ03553.1 - 0.0044 17.1 0.1 2.5 8.2 0.0 2.5 2 0 0 2 2 2 2 Dda helicase SH3 domain FMN_dh PF01070.18 ORZ03554.1 - 0.029 13.4 0.6 0.049 12.7 0.6 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IMS PF00817.20 ORZ03555.1 - 1.8e-43 148.1 0.0 6.4e-43 146.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family BRCT_2 PF16589.5 ORZ03555.1 - 7.1e-15 55.2 0.0 2.4e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 ORZ03555.1 - 2.2e-13 50.9 0.0 7.2e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 ORZ03555.1 - 1.4e-10 41.4 2.3 1.9e-10 41.0 0.8 2.1 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain BRCT PF00533.26 ORZ03555.1 - 9.8e-09 35.5 0.0 2.3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ORZ03555.1 - 2e-08 34.4 0.0 5.4e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 ORZ03555.1 - 1.6e-07 31.2 0.0 2.5e-06 27.5 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif UBM PF14377.6 ORZ03555.1 - 3.9e-05 23.0 6.4 0.061 12.8 0.5 3.9 3 0 0 3 3 3 2 Ubiquitin binding region PTCB-BRCT PF12738.7 ORZ03555.1 - 7.7e-05 22.6 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Cdd1 PF11731.8 ORZ03555.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus mCpol PF18182.1 ORZ03555.1 - 0.038 14.3 0.4 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 minimal CRISPR polymerase domain STIMATE PF12400.8 ORZ03556.1 - 1.7e-39 135.2 6.4 2.7e-39 134.6 6.4 1.3 1 0 0 1 1 1 1 STIMATE family Polysacc_deac_1 PF01522.21 ORZ03557.1 - 6.5e-07 29.3 0.2 1.1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase VirE_N PF08800.10 ORZ03557.1 - 0.077 13.1 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 VirE N-terminal domain UCH PF00443.29 ORZ03558.1 - 2.7e-11 43.5 0.0 8.6e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF713 PF05218.14 ORZ03558.1 - 0.024 14.4 0.4 0.056 13.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF713) DUF1514 PF07438.11 ORZ03558.1 - 0.054 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) UCH_1 PF13423.6 ORZ03558.1 - 0.31 10.6 1.4 17 4.9 0.1 2.6 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase GTP_EFTU PF00009.27 ORZ03559.1 - 8.4e-66 221.2 0.2 1.2e-65 220.7 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORZ03559.1 - 1.2e-31 109.1 0.0 4.6e-31 107.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 ORZ03559.1 - 5e-22 77.8 0.0 1.3e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORZ03559.1 - 9.9e-14 51.5 0.1 3.1e-13 49.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORZ03559.1 - 1.6e-13 50.5 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORZ03559.1 - 0.00012 22.1 0.1 0.00026 21.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1640 PF07798.11 ORZ03561.1 - 7e-44 149.9 3.1 7e-44 149.9 3.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Phage_holin_2_4 PF16082.5 ORZ03561.1 - 0.0062 16.2 0.2 0.012 15.4 0.2 1.4 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like SNARE_assoc PF09335.11 ORZ03561.1 - 0.037 14.5 0.1 0.06 13.8 0.1 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF5403 PF17395.2 ORZ03561.1 - 0.073 13.4 0.3 0.21 11.9 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5403) LapA_dom PF06305.11 ORZ03561.1 - 0.085 12.7 0.1 0.26 11.1 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2660 PF10859.8 ORZ03561.1 - 0.095 13.2 1.4 0.24 11.9 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF2062 PF09835.9 ORZ03561.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Hemagglutinin PF00509.18 ORZ03561.1 - 0.34 9.2 2.4 0.66 8.3 2.4 1.3 1 0 0 1 1 1 0 Haemagglutinin DUF3824 PF12868.7 ORZ03561.1 - 3 8.5 9.7 0.29 11.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Gtr1_RagA PF04670.12 ORZ03562.1 - 6.8e-101 336.5 0.1 8.3e-101 336.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORZ03562.1 - 5.8e-09 36.2 0.0 1.4e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORZ03562.1 - 9.6e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 ORZ03562.1 - 1.2e-07 31.4 0.1 2.8e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORZ03562.1 - 1.5e-06 28.3 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORZ03562.1 - 0.019 14.7 0.3 0.084 12.6 0.1 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 ORZ03562.1 - 0.023 14.6 0.1 3 7.7 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 ORZ03562.1 - 0.024 15.1 0.6 0.059 13.9 0.3 2.0 2 1 0 2 2 2 0 ABC transporter SRPRB PF09439.10 ORZ03562.1 - 0.046 13.1 0.0 0.085 12.3 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 ORZ03562.1 - 0.057 12.6 0.6 0.19 10.9 0.0 2.1 3 1 1 4 4 4 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORZ03562.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ORZ03562.1 - 4.2 6.4 8.4 7.3 5.6 0.1 2.9 2 2 1 3 3 3 0 G-protein alpha subunit NUFIP1 PF10453.9 ORZ03563.1 - 6.8e-13 48.3 3.6 6.8e-13 48.3 3.6 2.5 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 ORZ03563.1 - 9e-06 25.4 2.9 9e-06 25.4 2.9 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 ORZ03563.1 - 0.00028 20.7 3.9 0.00028 20.7 3.9 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORZ03563.1 - 0.00033 20.6 5.4 0.00033 20.6 5.4 1.8 2 0 0 2 2 2 1 Zinc finger domain TFIIA PF03153.13 ORZ03563.1 - 0.0019 18.3 19.7 0.0027 17.8 19.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-CCCH_2 PF14608.6 ORZ03563.1 - 0.0095 16.4 2.9 0.0095 16.4 2.9 2.1 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-C2H2_4 PF13894.6 ORZ03563.1 - 2.6 9.1 9.2 11 7.1 0.8 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger Torus PF16131.5 ORZ03563.1 - 5.4 7.8 10.1 2.1 9.1 5.3 2.7 2 1 0 2 2 2 0 Torus domain DUF3340 PF11818.8 ORZ03564.1 - 0.23 11.6 0.0 0.29 11.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DAO PF01266.24 ORZ03565.1 - 2.1e-60 205.2 0.1 2.3e-60 205.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORZ03565.1 - 0.00089 19.4 0.1 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 ORZ03565.1 - 0.049 13.9 0.2 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORZ03565.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 ORZ03565.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pkinase PF00069.25 ORZ03566.1 - 2.3e-78 263.2 0.0 2.7e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03566.1 - 7.4e-33 113.9 0.0 9.2e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORZ03566.1 - 2.8e-06 26.5 0.1 9.1e-06 24.8 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORZ03566.1 - 0.00022 20.6 0.2 0.0066 15.8 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORZ03566.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ish1 PF10281.9 ORZ03566.1 - 0.032 14.5 0.0 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein APH PF01636.23 ORZ03566.1 - 0.091 12.7 0.1 0.46 10.4 0.0 1.9 2 1 0 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORZ03566.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_2 PF12796.7 ORZ03567.1 - 4.3e-14 52.9 0.0 3.2e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORZ03567.1 - 8.3e-10 38.7 0.0 5.1e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORZ03567.1 - 8.4e-10 38.7 0.0 0.0002 21.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORZ03567.1 - 1.4e-09 38.3 0.0 0.00022 21.7 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ03567.1 - 3.5e-08 33.1 0.0 0.00053 20.2 0.0 3.8 4 1 0 4 4 4 2 Ankyrin repeat RNaseH_pPIWI_RE PF13032.6 ORZ03567.1 - 0.083 12.8 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE HBS1_N PF08938.10 ORZ03567.1 - 0.7 10.2 6.3 1.5 9.2 6.3 1.6 1 0 0 1 1 1 0 HBS1 N-terminus fn3_2 PF16893.5 ORZ03568.1 - 2.3e-31 107.8 0.0 4e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 ORZ03568.1 - 1e-26 92.6 0.1 1.6e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 ORZ03568.1 - 6.4e-15 54.9 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORZ03568.1 - 9.2e-13 48.4 0.0 1.7e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 ORZ03568.1 - 5.3e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 ORZ03568.1 - 1.3e-05 25.5 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 ORZ03568.1 - 1.5e-05 25.1 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_3 PF18428.1 ORZ03568.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.22 ORZ03569.1 - 6.6e-18 64.3 0.0 9.8e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ03569.1 - 0.01 15.9 0.0 0.024 14.8 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Nup35_RRM PF05172.13 ORZ03569.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_S9 PF00380.19 ORZ03570.1 - 2.5e-45 153.9 0.1 4.5e-45 153.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CSN7a_helixI PF18392.1 ORZ03571.1 - 0.046 13.6 1.1 0.075 13.0 1.1 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain tRNA_m1G_MT PF01746.21 ORZ03572.1 - 4.9e-31 107.9 0.4 1.2e-30 106.7 0.4 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Serinc PF03348.15 ORZ03572.1 - 0.93 8.3 1.9 1.5 7.7 1.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DNA_pol_phi PF04931.13 ORZ03572.1 - 2.9 5.9 18.5 5.2 5.0 18.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 ORZ03572.1 - 9.8 4.3 22.0 0.083 11.2 11.1 2.0 2 0 0 2 2 2 0 CDC45-like protein Suf PF05843.14 ORZ03573.1 - 1 9.3 8.1 1.2 9.1 8.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 ORZ03573.1 - 1.4 8.5 14.7 2.8 7.5 14.7 1.5 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 ORZ03573.1 - 2.3 6.9 6.8 2.6 6.7 6.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 ORZ03573.1 - 4.1 8.4 8.0 6.7 7.7 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ebp2 PF05890.12 ORZ03574.1 - 4.5e-16 59.2 0.7 4.5e-16 59.2 0.7 2.4 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF3807 PF12720.7 ORZ03574.1 - 1.9 8.7 13.9 0.19 12.0 9.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3807) zf-H2C2_2 PF13465.6 ORZ03575.1 - 8.1e-08 32.4 4.1 5.5e-06 26.6 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORZ03575.1 - 1.1e-07 31.9 16.3 0.00017 21.8 0.1 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03575.1 - 0.00032 21.3 12.2 0.016 16.0 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ03575.1 - 0.00064 20.3 6.5 0.02 15.5 0.1 3.9 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORZ03575.1 - 0.002 18.1 0.1 0.002 18.1 0.1 3.4 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORZ03575.1 - 0.0035 17.6 3.1 0.85 10.0 0.6 2.8 1 1 2 3 3 3 3 C2H2-type zinc ribbon Zap1_zf2 PF18217.1 ORZ03575.1 - 0.17 11.9 6.6 0.65 10.1 0.8 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf_ZIC PF18366.1 ORZ03575.1 - 0.18 11.9 8.2 0.17 12.0 0.8 3.3 3 1 0 3 3 3 0 Zic proteins zinc finger domain TerB_C PF15615.6 ORZ03575.1 - 1.8 8.9 12.0 0.94 9.8 3.5 2.8 2 1 1 3 3 3 0 TerB-C domain Gemini_mov PF01708.16 ORZ03576.1 - 2.4 8.0 4.9 0.32 10.8 0.8 1.6 2 0 0 2 2 2 0 Geminivirus putative movement protein TMEM51 PF15345.6 ORZ03577.1 - 0.00087 19.2 0.3 0.00095 19.1 0.1 1.2 1 1 0 1 1 1 1 Transmembrane protein 51 DUF1970 PF09301.10 ORZ03577.1 - 0.0099 16.1 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1970) DUF4381 PF14316.6 ORZ03577.1 - 0.053 13.8 1.0 0.076 13.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RCR PF12273.8 ORZ03577.1 - 0.14 12.8 6.1 0.32 11.6 6.1 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MHYT PF03707.16 ORZ03577.1 - 0.16 12.1 1.3 0.23 11.7 1.3 1.3 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF2207 PF09972.9 ORZ03577.1 - 0.23 10.2 0.0 0.23 10.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CcmD PF04995.14 ORZ03577.1 - 0.68 10.1 7.3 1 9.5 7.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) GalP_UDP_transf PF01087.22 ORZ03578.1 - 5.6e-71 238.8 0.7 2.5e-70 236.6 0.8 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 ORZ03578.1 - 1.3e-63 213.7 0.0 2.4e-63 212.8 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 ORZ03578.1 - 1.5e-05 25.4 0.1 3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORZ03578.1 - 1.9e-05 25.3 0.6 0.0005 20.8 0.1 2.3 2 0 0 2 2 2 1 HIT domain DUF4921 PF16268.5 ORZ03578.1 - 0.0064 15.4 0.4 0.18 10.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4921) CryBP1 PF07029.11 ORZ03578.1 - 0.076 13.1 0.7 0.12 12.4 0.1 1.6 2 0 0 2 2 2 0 CryBP1 protein RGI1 PF10843.8 ORZ03578.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Respiratory growth induced protein 1 DUF4931 PF16285.5 ORZ03578.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) zf-C2H2 PF00096.26 ORZ03579.1 - 5.6e-16 58.0 21.3 6.4e-07 29.5 4.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03579.1 - 1.1e-13 50.8 18.4 0.00012 22.7 0.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORZ03579.1 - 8.8e-13 48.1 23.1 1.1e-05 25.6 2.1 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ03579.1 - 5.7e-09 35.8 3.3 1.3e-05 25.0 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORZ03579.1 - 3.2e-06 27.3 6.1 0.0016 18.7 1.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORZ03579.1 - 6.3e-05 23.2 10.1 0.032 14.5 0.0 3.4 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORZ03579.1 - 0.0095 15.7 18.5 0.28 11.0 4.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zinc-ribbons_6 PF07191.12 ORZ03579.1 - 0.036 14.0 2.5 0.68 10.0 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 ORZ03579.1 - 0.054 13.6 10.6 0.86 9.8 1.6 3.3 3 0 0 3 3 3 0 Zinc ribbon domain DUF2197 PF09963.9 ORZ03579.1 - 0.17 12.2 6.0 0.28 11.5 1.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) CpXC PF14353.6 ORZ03579.1 - 0.18 11.8 2.2 15 5.6 0.2 2.8 3 0 0 3 3 3 0 CpXC protein zf-C2H2_11 PF16622.5 ORZ03579.1 - 1.3 8.9 11.4 0.8 9.5 0.1 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Ogr_Delta PF04606.12 ORZ03579.1 - 1.5 8.9 0.0 1.5 8.9 0.0 3.6 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger DUF2256 PF10013.9 ORZ03579.1 - 2.1 8.5 8.0 0.5 10.5 1.8 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) OrfB_Zn_ribbon PF07282.11 ORZ03579.1 - 7.7 6.5 6.4 3.2 7.8 0.8 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain EMC1_C PF07774.13 ORZ03581.1 - 8.9e-69 231.4 0.0 1.5e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 ORZ03581.1 - 2.2e-09 37.3 8.3 1.5e-08 34.5 1.3 4.2 4 1 0 4 4 4 1 PQQ-like domain PQQ PF01011.21 ORZ03581.1 - 0.022 14.7 0.3 9.2 6.4 0.1 4.5 5 0 0 5 5 5 0 PQQ enzyme repeat DUF262 PF03235.14 ORZ03582.1 - 2.7e-16 60.4 0.2 2.7e-14 53.9 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function DUF262 DndB PF14072.6 ORZ03582.1 - 0.00092 18.5 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 DNA-sulfur modification-associated Ank_2 PF12796.7 ORZ03583.1 - 1.1e-23 83.6 0.3 3.1e-16 59.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORZ03583.1 - 4.7e-21 74.6 0.2 2.6e-10 40.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORZ03583.1 - 1.6e-18 66.8 0.3 2.9e-14 53.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ03583.1 - 8.7e-16 56.4 0.0 5.3e-07 29.4 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ORZ03583.1 - 7.5e-14 51.5 2.8 3.2e-06 27.3 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeat PARP PF00644.20 ORZ03584.1 - 2.4e-48 164.3 0.0 5e-48 163.3 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank_2 PF12796.7 ORZ03584.1 - 7.1e-23 81.0 6.1 2.3e-10 40.9 0.2 6.4 4 2 3 7 7 7 5 Ankyrin repeats (3 copies) WGR PF05406.15 ORZ03584.1 - 9.5e-14 51.2 0.0 9.5e-14 51.2 0.0 2.2 3 0 0 3 3 3 1 WGR domain Ank_4 PF13637.6 ORZ03584.1 - 1.3e-13 51.2 4.0 0.00075 20.0 0.1 6.6 7 0 0 7 7 7 3 Ankyrin repeats (many copies) PARP_reg PF02877.14 ORZ03584.1 - 1.3e-13 51.2 0.1 2.5e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Ank_5 PF13857.6 ORZ03584.1 - 2.8e-12 46.6 4.6 0.0022 18.2 0.1 6.2 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORZ03584.1 - 2.2e-10 39.8 6.9 0.017 15.6 0.0 8.4 10 0 0 10 10 10 1 Ankyrin repeat Ank PF00023.30 ORZ03584.1 - 0.00029 21.2 10.1 2.3 8.8 0.1 6.3 7 0 0 7 7 7 2 Ankyrin repeat zf-CCHH PF10283.9 ORZ03585.1 - 0.00075 19.4 8.1 0.00099 19.0 8.1 1.2 1 0 0 1 1 1 1 PBZ domain Astro_capsid_p PF12226.8 ORZ03585.1 - 0.39 9.8 3.3 0.4 9.8 3.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Molybdopterin PF00384.22 ORZ03586.1 - 1.3e-60 205.7 0.0 7.6e-60 203.1 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 ORZ03586.1 - 4.1e-19 68.4 0.3 1.3e-18 66.8 0.3 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 ORZ03586.1 - 4.6e-16 58.1 0.2 4.6e-16 58.1 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 ORZ03586.1 - 1.4e-14 54.5 1.0 2.8e-14 53.5 0.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 ORZ03586.1 - 3e-08 33.5 0.4 3e-08 33.5 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ORZ03586.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain zf-H2C2_2 PF13465.6 ORZ03587.1 - 9.8e-12 44.7 3.3 4e-08 33.3 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORZ03587.1 - 1e-09 38.3 7.8 0.00023 21.4 3.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03587.1 - 1.1e-07 32.0 6.1 0.0036 18.0 2.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORZ03587.1 - 0.00064 19.4 3.9 0.018 14.8 0.0 2.7 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2HE PF16278.5 ORZ03587.1 - 0.0023 18.3 1.4 0.36 11.3 1.4 2.4 1 1 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORZ03587.1 - 0.0051 17.1 0.7 0.37 11.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 ORZ03587.1 - 0.02 15.1 0.6 5.4 7.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_2 PF12756.7 ORZ03587.1 - 0.37 11.1 5.4 0.71 10.2 0.6 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORZ03587.1 - 0.38 10.6 11.6 0.097 12.4 1.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 ORZ03587.1 - 0.83 9.6 7.5 6.3 6.8 1.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CHY PF05495.12 ORZ03587.1 - 2.3 8.8 7.2 2.9 8.5 3.7 2.3 1 1 1 2 2 2 0 CHY zinc finger Rad21_Rec8 PF04824.16 ORZ03588.1 - 7.5e-07 28.3 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein JAB PF01398.21 ORZ03589.1 - 1.3e-21 76.8 0.2 3e-21 75.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 ORZ03589.1 - 2.3e-09 37.1 0.3 4.6e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain BRCC36_C PF18110.1 ORZ03589.1 - 3.5e-09 36.7 0.6 7.6e-09 35.6 0.6 1.6 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain MFS_1 PF07690.16 ORZ03590.1 - 8.8e-16 57.8 40.0 6.9e-10 38.4 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_16 PF10294.9 ORZ03591.1 - 3.3e-35 121.4 0.0 5.2e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 ORZ03591.1 - 0.00012 22.7 0.0 0.00019 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03591.1 - 0.0018 18.1 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ03591.1 - 0.0033 18.2 0.0 0.005 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORZ03591.1 - 0.039 13.5 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 ORZ03591.1 - 0.056 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tctex-1 PF03645.13 ORZ03592.1 - 4.1e-33 113.7 0.4 4.7e-33 113.5 0.4 1.0 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M16_C PF05193.21 ORZ03593.1 - 3.5e-23 82.6 0.0 8.7e-14 51.9 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORZ03593.1 - 8.8e-09 35.5 0.4 1.8e-06 28.0 0.0 3.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 ORZ03593.1 - 1.4 8.0 11.7 7.4 5.6 3.9 3.7 3 2 1 4 4 4 0 Peptidase M16C associated Sec23_trunk PF04811.15 ORZ03594.1 - 7.3e-67 225.5 0.0 1.4e-66 224.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORZ03594.1 - 9.4e-22 76.8 0.0 2.8e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORZ03594.1 - 1e-17 64.7 0.0 1.9e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORZ03594.1 - 5.9e-16 58.2 2.4 5.9e-16 58.2 2.4 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORZ03594.1 - 6e-08 32.5 1.4 9.5e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORZ03594.1 - 0.026 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TFIIA PF03153.13 ORZ03594.1 - 8.9 6.2 26.4 13 5.6 26.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RSN1_7TM PF02714.15 ORZ03595.1 - 2.4e-67 227.2 26.2 2.4e-67 227.2 26.2 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORZ03595.1 - 3.1e-34 118.0 0.2 3.1e-34 118.0 0.2 3.0 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORZ03595.1 - 6.5e-29 101.4 0.0 1.5e-28 100.2 0.0 1.7 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DASH_Ask1 PF08655.10 ORZ03596.1 - 4.4e-17 61.7 0.3 9.4e-17 60.7 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 MCM2_N PF12619.8 ORZ03596.1 - 5.3 7.3 8.9 2.6 8.3 0.7 3.3 2 1 1 3 3 3 0 Mini-chromosome maintenance protein 2 Ribosomal_L11_N PF03946.14 ORZ03597.1 - 9e-23 79.9 0.1 2.1e-22 78.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORZ03597.1 - 8e-19 67.9 0.1 1.2e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Methyltransf_PK PF05891.12 ORZ03598.1 - 3.7e-80 268.5 0.0 4.4e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORZ03598.1 - 8.5e-12 45.6 0.1 1.6e-11 44.7 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03598.1 - 2e-09 38.0 0.0 3.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ03598.1 - 1.2e-08 34.9 0.0 4.5e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORZ03598.1 - 2.2e-07 31.5 0.0 3.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03598.1 - 0.0012 18.7 0.1 0.0016 18.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORZ03598.1 - 0.0018 17.6 0.1 0.0023 17.3 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Bin3 PF06859.12 ORZ03598.1 - 0.0094 16.6 0.0 0.018 15.7 0.0 1.5 1 1 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) CMAS PF02353.20 ORZ03598.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 ORZ03598.1 - 0.19 10.8 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Peptidase_S10 PF00450.22 ORZ03599.1 - 8e-112 374.7 0.1 1.1e-111 374.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4131 PF13567.6 ORZ03599.1 - 0.002 17.8 0.2 0.15 11.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) SelR PF01641.18 ORZ03599.1 - 0.022 14.9 0.1 0.055 13.6 0.1 1.7 1 0 0 1 1 1 0 SelR domain FeoB_associated PF12669.7 ORZ03599.1 - 0.043 14.2 0.1 0.099 13.1 0.1 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF1769 PF08588.10 ORZ03600.1 - 3.4e-19 68.8 0.1 9.6e-19 67.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DUF1441 PF07278.11 ORZ03600.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) eIF-5_eIF-2B PF01873.17 ORZ03601.1 - 1.2e-41 141.3 0.0 2.5e-41 140.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 ORZ03601.1 - 9.1e-22 77.0 0.5 9.1e-22 77.0 0.5 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon TipAS PF07739.13 ORZ03601.1 - 1.5 9.4 5.3 0.58 10.7 1.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Vma12 PF11712.8 ORZ03602.1 - 6.1 6.9 4.9 1.3 9.1 0.7 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Chitin_synth_2 PF03142.15 ORZ03603.1 - 1.3e-229 763.2 1.0 1.9e-229 762.7 1.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORZ03603.1 - 3.1e-70 237.2 0.0 1.5e-55 188.7 0.0 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 ORZ03603.1 - 2.6e-18 65.6 1.3 1.5e-16 60.0 0.1 2.9 3 0 0 3 3 3 1 DEK C terminal domain Cyt-b5 PF00173.28 ORZ03603.1 - 1.9e-16 60.0 0.6 1.4e-13 50.7 0.1 3.3 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 ORZ03603.1 - 1.3e-11 44.8 0.0 9.4e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORZ03603.1 - 2.5e-09 37.4 2.7 2.5e-09 37.4 2.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORZ03603.1 - 0.00094 19.0 0.0 0.034 14.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORZ03603.1 - 0.0066 15.9 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Mlh1_C PF16413.5 ORZ03603.1 - 0.12 11.7 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus DUF2076 PF09849.9 ORZ03604.1 - 0.15 12.1 10.3 0.15 12.0 10.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) EamA PF00892.20 ORZ03605.1 - 9.9e-20 71.1 24.9 7e-11 42.5 4.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 ORZ03605.1 - 0.022 14.8 0.7 0.022 14.8 0.7 2.3 2 1 0 2 2 2 0 Putative transmembrane family 234 DHH PF01368.20 ORZ03605.1 - 0.025 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 DHH family TPT PF03151.16 ORZ03605.1 - 0.21 10.9 4.8 0.25 10.6 2.2 2.0 1 1 0 2 2 2 0 Triose-phosphate Transporter family Multi_Drug_Res PF00893.19 ORZ03605.1 - 0.25 12.0 11.3 0.72 10.6 1.6 3.6 2 2 1 3 3 3 0 Small Multidrug Resistance protein DoxX_2 PF13564.6 ORZ03605.1 - 6.8 6.9 16.8 2.3 8.4 0.7 3.5 3 1 1 4 4 4 0 DoxX-like family CM_2 PF01817.21 ORZ03606.1 - 0.042 14.2 0.7 0.85 10.0 0.0 2.5 2 1 0 2 2 2 0 Chorismate mutase type II TH1 PF04858.13 ORZ03607.1 - 1.5e-71 241.8 0.2 1.9e-71 241.5 0.2 1.0 1 0 0 1 1 1 1 TH1 protein DUF2009 PF09418.10 ORZ03608.1 - 4.1e-192 639.3 0.0 5.2e-192 638.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 ORZ03608.1 - 8.9e-05 22.6 7.1 0.00018 21.6 7.1 1.6 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 ORZ03608.1 - 0.02 15.2 6.7 0.057 13.7 6.7 1.8 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF4859 PF16151.5 ORZ03608.1 - 0.064 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) Viral_DNA_bp PF00747.17 ORZ03608.1 - 0.56 7.3 3.3 0.73 6.9 3.3 1.1 1 0 0 1 1 1 0 ssDNA binding protein IBR PF01485.21 ORZ03608.1 - 0.76 10.0 9.0 3 8.1 9.0 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain NOB1_Zn_bind PF08772.11 ORZ03608.1 - 1.2 9.4 5.8 0.69 10.1 3.1 2.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CP2 PF04516.15 ORZ03609.1 - 9.5e-47 159.2 2.3 1e-34 119.8 0.0 2.2 1 1 1 2 2 2 2 CP2 transcription factor p450 PF00067.22 ORZ03610.1 - 3.2e-69 233.9 0.0 4.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1912 PF08930.10 ORZ03610.1 - 0.058 13.6 0.2 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) WD40 PF00400.32 ORZ03612.1 - 3.5e-59 195.4 7.5 6.2e-08 33.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORZ03612.1 - 1.1e-26 92.9 12.4 1.6e-26 92.4 12.4 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORZ03612.1 - 6.9e-19 68.0 0.0 0.00028 21.1 0.0 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ03612.1 - 3.3e-08 33.2 0.0 0.0043 16.4 0.0 4.1 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 ORZ03612.1 - 1.5e-07 30.7 0.1 0.43 9.5 0.0 4.6 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORZ03612.1 - 0.00039 19.1 0.4 0.052 12.1 0.1 2.6 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.6 ORZ03612.1 - 0.00058 19.3 0.1 3.7 6.8 0.0 3.2 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal CEP63 PF17045.5 ORZ03612.1 - 0.0036 17.3 4.9 0.0052 16.7 4.9 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa PD40 PF07676.12 ORZ03612.1 - 0.012 15.5 2.4 3.7 7.6 0.1 4.0 4 0 0 4 4 3 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 ORZ03612.1 - 0.017 14.9 0.3 0.13 12.0 0.0 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Spc7 PF08317.11 ORZ03612.1 - 0.02 13.8 5.4 0.029 13.3 5.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup160 PF11715.8 ORZ03612.1 - 0.028 13.1 1.3 1.1 7.9 0.0 3.6 3 1 3 6 6 6 0 Nucleoporin Nup120/160 Ret2_MD PF18528.1 ORZ03612.1 - 0.039 14.3 0.0 41 4.7 0.0 3.6 3 2 1 4 4 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain MMS1_N PF10433.9 ORZ03612.1 - 0.056 12.1 0.0 2.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term F_actin_bind PF08919.10 ORZ03612.1 - 0.076 13.1 1.3 0.12 12.4 1.3 1.2 1 0 0 1 1 1 0 F-actin binding Golgin_A5 PF09787.9 ORZ03612.1 - 0.089 12.2 6.6 0.19 11.1 6.6 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Proteasome_A_N PF10584.9 ORZ03612.1 - 0.16 11.7 1.2 84 3.0 0.2 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Herpes_UL25 PF01499.16 ORZ03612.1 - 0.19 10.2 0.2 0.28 9.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF5122 PF17164.4 ORZ03612.1 - 0.23 11.8 1.4 51 4.3 0.0 4.4 6 0 0 6 6 4 0 Domain of unknown function (DUF5122) beta-propeller DUF724 PF05266.14 ORZ03612.1 - 0.32 10.8 4.3 0.48 10.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CREPT PF16566.5 ORZ03612.1 - 0.7 10.1 6.6 1.2 9.3 6.6 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2524 PF10732.9 ORZ03612.1 - 0.77 10.1 10.1 4.1 7.8 10.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) TPX2 PF06886.11 ORZ03612.1 - 0.97 9.7 4.4 1.7 8.9 4.4 1.4 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) DUF3450 PF11932.8 ORZ03612.1 - 2.2 7.5 9.7 4.2 6.6 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-C2H2_4 PF13894.6 ORZ03613.1 - 0.00032 21.3 15.5 0.0021 18.8 1.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORZ03613.1 - 0.00098 19.1 0.2 0.00098 19.1 0.2 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.12 ORZ03613.1 - 0.02 13.4 1.9 0.16 10.5 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 ORZ03613.1 - 0.27 11.6 4.2 9.2 6.7 1.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ORZ03613.1 - 1 9.9 14.8 3.8 8.2 5.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type YchF-GTPase_C PF06071.13 ORZ03614.1 - 2.6e-38 130.1 0.7 5.3e-38 129.1 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORZ03614.1 - 1.9e-19 69.8 0.0 3.8e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORZ03614.1 - 6.5e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 ORZ03614.1 - 0.0047 16.9 0.1 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 TGS domain MeaB PF03308.16 ORZ03614.1 - 0.041 12.9 0.1 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 ORZ03614.1 - 0.063 13.3 0.1 4.3 7.4 0.1 2.4 1 1 1 2 2 2 0 Dynamin family TFR_dimer PF04253.15 ORZ03615.1 - 3.6e-28 98.1 0.0 5.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORZ03615.1 - 2.9e-19 69.5 0.0 5.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORZ03615.1 - 4.8e-11 42.5 0.0 1.3e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORZ03615.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 STAT1_TAZ2bind PF12162.8 ORZ03615.1 - 0.61 9.7 3.6 0.4 10.3 0.3 2.3 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain UBX PF00789.20 ORZ03616.1 - 9.9e-09 35.3 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF3446 PF11928.8 ORZ03616.1 - 0.66 10.3 18.1 0.054 13.8 7.3 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain BES1_N PF05687.13 ORZ03616.1 - 1.9 8.9 7.7 0.25 11.7 1.4 2.1 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal La PF05383.17 ORZ03617.1 - 5.4e-21 74.4 0.6 1.1e-20 73.4 0.6 1.6 1 0 0 1 1 1 1 La domain DUF2407_C PF13373.6 ORZ03617.1 - 2.4 8.4 6.4 0.27 11.4 0.7 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain ATP-synt_J PF04911.12 ORZ03618.1 - 2.7e-23 81.3 0.4 2.9e-23 81.2 0.4 1.0 1 0 0 1 1 1 1 ATP synthase j chain YjeF_N PF03853.15 ORZ03619.1 - 9.3e-40 136.3 0.0 1.2e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF2802 PF10975.8 ORZ03619.1 - 0.043 13.9 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Chorismate_bind PF00425.18 ORZ03620.1 - 5.1e-82 275.3 0.0 7.3e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 ORZ03620.1 - 3.8e-34 118.1 0.0 4.4e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 ORZ03620.1 - 9e-12 45.4 0.2 1.3e-10 41.6 0.1 2.7 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 ORZ03620.1 - 0.0027 17.5 0.8 0.3 10.8 0.1 2.6 2 1 0 2 2 2 2 Peptidase C26 AMP-binding PF00501.28 ORZ03621.1 - 1.1e-36 126.3 0.0 1.6e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORZ03621.1 - 1.6e-35 122.5 0.0 5.8e-35 120.7 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 ORZ03621.1 - 2.3e-11 43.9 0.0 6.2e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORZ03621.1 - 1.1e-05 25.1 0.0 5.1e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORZ03621.1 - 0.019 14.1 0.1 0.075 12.2 0.0 2.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein FMP23 PF17315.2 ORZ03621.1 - 0.058 13.6 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Found in mitochondrial proteome DXP_reductoisom PF02670.16 ORZ03621.1 - 0.12 13.1 0.0 0.44 11.3 0.0 1.9 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PIG-F PF06699.11 ORZ03622.1 - 4.7e-35 121.4 10.6 5.5e-35 121.1 10.6 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F HECT PF00632.25 ORZ03623.1 - 1.9e-91 306.8 0.0 3.6e-91 305.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1729 PF08354.10 ORZ03623.1 - 0.03 13.2 0.2 0.052 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) IQ PF00612.27 ORZ03623.1 - 0.078 12.8 2.5 0.29 11.0 2.5 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF2850 PF11012.8 ORZ03623.1 - 0.1 12.9 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) CDC27 PF09507.10 ORZ03625.1 - 1.9 7.8 48.5 0.19 11.1 43.3 1.7 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 zf-PARP PF00645.18 ORZ03626.1 - 3.3e-22 79.1 0.5 4.1e-22 78.8 0.5 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF1296 PF06972.11 ORZ03626.1 - 0.039 14.1 0.2 0.064 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Merozoite_SPAM PF07133.11 ORZ03627.1 - 0.001 19.1 24.3 0.0013 18.8 24.3 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CobT PF06213.12 ORZ03627.1 - 0.13 11.6 22.9 0.16 11.3 22.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 ORZ03627.1 - 0.14 10.2 23.3 0.15 10.2 23.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 ORZ03627.1 - 0.53 8.4 29.4 0.57 8.3 29.4 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 ORZ03627.1 - 0.61 9.2 16.6 0.61 9.2 16.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 ORZ03627.1 - 0.74 8.7 32.9 0.96 8.4 32.9 1.1 1 0 0 1 1 1 0 Paf1 DUF5427 PF10310.9 ORZ03627.1 - 2.2 7.1 26.7 2.5 7.0 26.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4746 PF15928.5 ORZ03627.1 - 2.6 7.4 22.4 2.7 7.3 22.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 ORZ03627.1 - 2.7 6.2 29.4 3 6.0 29.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 ORZ03627.1 - 2.8 8.2 29.4 3.8 7.8 29.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDRGK PF09756.9 ORZ03627.1 - 3 7.4 33.4 3.4 7.2 33.4 1.2 1 0 0 1 1 1 0 DDRGK domain SpoIIIAH PF12685.7 ORZ03627.1 - 3.2 7.5 22.2 4.2 7.2 22.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF913 PF06025.12 ORZ03627.1 - 4 6.3 16.3 3.9 6.4 16.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TLP-20 PF06088.11 ORZ03627.1 - 4.2 7.2 16.0 5.5 6.8 16.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2151 PF10221.9 ORZ03627.1 - 4.5 5.7 19.7 4.6 5.7 19.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Spore_coat_CotO PF14153.6 ORZ03627.1 - 4.6 7.1 25.1 5.1 7.0 25.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.12 ORZ03627.1 - 5.6 6.7 30.6 6.6 6.5 30.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 ORZ03627.1 - 7.1 6.6 15.8 8 6.4 15.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 ORZ03627.1 - 7.1 5.3 17.1 7.6 5.2 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 ORZ03627.1 - 8.1 5.1 24.2 8.9 5.0 24.2 1.1 1 0 0 1 1 1 0 Presenilin TEX19 PF15553.6 ORZ03627.1 - 9 6.2 8.6 10 6.0 8.6 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 YABBY PF04690.13 ORZ03627.1 - 9.7 6.7 10.6 11 6.5 10.6 1.2 1 0 0 1 1 1 0 YABBY protein WD40 PF00400.32 ORZ03628.1 - 4e-31 106.6 15.9 8e-08 32.8 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03628.1 - 1.1e-06 28.9 0.7 1.4 9.3 0.0 5.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ03628.1 - 2.7e-06 27.4 0.0 3.9e-05 23.6 0.0 2.3 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDC45 PF02724.14 ORZ03628.1 - 0.00072 18.0 14.0 0.0011 17.4 14.0 1.1 1 0 0 1 1 1 1 CDC45-like protein LisH_TPL PF17814.1 ORZ03628.1 - 0.0013 18.3 0.3 0.0029 17.2 0.3 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain SprA-related PF12118.8 ORZ03628.1 - 1.6 7.8 16.7 2.3 7.3 16.7 1.2 1 0 0 1 1 1 0 SprA-related family RNA_pol_Rpc4 PF05132.14 ORZ03628.1 - 2.9 8.3 8.4 5.4 7.4 8.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.17 ORZ03628.1 - 4 7.6 6.5 9.8 6.3 6.5 1.6 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 ORZ03628.1 - 5.1 7.1 5.5 8.5 6.4 5.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Maelstrom PF13017.6 ORZ03629.1 - 0.04 13.6 0.6 0.064 12.9 0.6 1.3 1 0 0 1 1 1 0 piRNA pathway germ-plasm component JAB PF01398.21 ORZ03630.1 - 8.4e-35 119.3 0.5 1.6e-34 118.4 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ORZ03630.1 - 1.9e-14 54.0 1.0 3.1e-14 53.3 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 ORZ03630.1 - 4e-06 26.6 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 ORZ03630.1 - 0.0078 16.3 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) KIP1 PF07765.12 ORZ03630.1 - 0.17 12.1 1.1 15 5.8 0.4 2.6 2 0 0 2 2 2 0 KIP1-like protein Chorismate_synt PF01264.21 ORZ03631.1 - 1.6e-140 467.5 0.0 1.9e-140 467.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase HSP20 PF00011.21 ORZ03632.1 - 1.6e-20 73.2 0.0 2.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORZ03632.1 - 3.3e-09 36.2 0.0 1.1e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 ORZ03633.1 - 7.6e-21 74.2 0.1 1.1e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORZ03633.1 - 2.9e-09 36.4 0.0 1.1e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DAO PF01266.24 ORZ03634.1 - 1.3e-46 159.8 0.0 1.5e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORZ03634.1 - 6.2e-08 32.8 0.0 3.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORZ03634.1 - 6.5e-06 25.6 0.0 0.094 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORZ03634.1 - 0.00025 21.1 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ORZ03634.1 - 0.00037 20.5 0.0 0.68 9.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 ORZ03634.1 - 0.0023 17.2 0.1 0.008 15.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 ORZ03634.1 - 0.0025 16.7 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 ORZ03634.1 - 0.0084 15.2 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORZ03634.1 - 0.0097 14.6 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein ApbA PF02558.16 ORZ03634.1 - 0.036 13.7 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 ORZ03634.1 - 0.048 12.7 0.0 2 7.4 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ORZ03634.1 - 0.056 12.7 0.0 0.44 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 ORZ03634.1 - 0.13 11.8 0.0 0.68 9.4 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 ORZ03634.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus tRNA-synt_2b PF00587.25 ORZ03635.1 - 9e-28 97.4 0.0 6.9e-26 91.3 0.0 2.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORZ03635.1 - 6.6e-13 48.8 9.1 1.1e-12 48.1 9.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 ORZ03635.1 - 0.066 12.1 0.5 0.085 11.8 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein tRNA-synt_2d PF01409.20 ORZ03635.1 - 0.089 12.3 0.2 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) YlqD PF11068.8 ORZ03635.1 - 0.54 10.6 10.9 0.96 9.8 10.9 1.3 1 0 0 1 1 1 0 YlqD protein Mod_r PF07200.13 ORZ03635.1 - 1.3 9.1 11.2 2.8 8.0 11.2 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2203 PF09969.9 ORZ03635.1 - 2 9.1 7.1 31 5.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 ORZ03635.1 - 3.6 6.9 7.9 7 5.9 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-MYND PF01753.18 ORZ03636.1 - 2.8e-06 27.3 12.2 2.8e-06 27.3 12.2 2.0 2 0 0 2 2 2 1 MYND finger TPR_1 PF00515.28 ORZ03636.1 - 2.8e-06 26.9 0.5 1e-05 25.1 0.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORZ03636.1 - 0.00045 20.2 0.1 0.0013 18.8 0.1 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ03636.1 - 0.0019 18.4 0.1 0.0052 17.0 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ03636.1 - 0.005 16.9 0.9 0.018 15.1 0.3 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORZ03636.1 - 0.42 10.6 3.1 0.83 9.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-B_box PF00643.24 ORZ03637.1 - 0.024 14.8 6.2 0.051 13.7 6.2 1.5 1 1 0 1 1 1 0 B-box zinc finger Adeno_hexon PF01065.19 ORZ03638.1 - 0.11 11.4 0.2 0.14 11.0 0.2 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain DNA_ligase_A_M PF01068.21 ORZ03639.1 - 3.1e-20 72.7 0.0 4.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 ORZ03639.1 - 9.8e-11 41.5 0.1 2e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain RNA_ligase PF09414.10 ORZ03639.1 - 0.0002 21.7 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_N PF04675.14 ORZ03639.1 - 0.00041 20.7 0.0 0.014 15.8 0.0 2.4 2 1 0 2 2 2 1 DNA ligase N terminus mRNA_cap_enzyme PF01331.19 ORZ03639.1 - 0.0024 17.7 0.0 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain MBD PF01429.19 ORZ03639.1 - 0.068 12.9 0.0 0.66 9.7 0.0 2.5 2 1 0 2 2 2 0 Methyl-CpG binding domain Methyltransf_11 PF08241.12 ORZ03640.1 - 3.7e-13 49.9 0.0 7.5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03640.1 - 5.1e-13 49.1 0.0 6.7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORZ03640.1 - 7e-13 49.1 0.0 2.6e-12 47.3 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain NodS PF05401.11 ORZ03640.1 - 2.2e-05 24.2 0.0 4.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 ORZ03640.1 - 4.2e-05 24.2 0.0 6.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORZ03640.1 - 0.0056 16.0 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORZ03640.1 - 0.04 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF3201 PF11447.8 ORZ03640.1 - 0.044 13.3 0.6 0.45 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) TPMT PF05724.11 ORZ03640.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TPT PF03151.16 ORZ03641.1 - 9.8e-27 94.0 15.0 1.2e-26 93.7 15.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORZ03641.1 - 2.1e-10 40.9 31.0 2.3e-07 31.1 7.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORZ03641.1 - 1.4e-05 24.5 15.1 2.3e-05 23.8 15.1 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport LcrR PF09621.10 ORZ03641.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) SLATT_1 PF18181.1 ORZ03641.1 - 0.21 11.5 0.6 2.1 8.3 0.2 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 UAA PF08449.11 ORZ03641.1 - 0.25 10.5 19.7 0.45 9.7 19.7 1.3 1 1 0 1 1 1 0 UAA transporter family DUF1129 PF06570.11 ORZ03641.1 - 1.3 8.5 7.0 0.085 12.3 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) zf-C2H2_jaz PF12171.8 ORZ03642.1 - 0.0025 18.1 0.4 0.0051 17.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORZ03642.1 - 0.026 14.9 0.2 0.05 14.0 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORZ03642.1 - 0.028 14.9 0.4 0.073 13.6 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORZ03642.1 - 0.03 15.2 0.3 0.077 13.9 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4328 PF14219.6 ORZ03642.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) zf-C2H2_11 PF16622.5 ORZ03642.1 - 0.17 11.6 0.8 0.33 10.7 0.8 1.3 1 0 0 1 1 1 0 zinc-finger C2H2-type Nup84_Nup100 PF04121.13 ORZ03643.1 - 8e-43 146.6 1.1 5.5e-42 143.8 0.3 1.9 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF3759 PF12585.8 ORZ03644.1 - 1e-35 121.6 5.1 1.2e-35 121.4 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2939 PF11159.8 ORZ03644.1 - 0.029 14.8 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF3759 PF12585.8 ORZ03645.1 - 9.6e-33 112.1 7.4 9.6e-33 112.1 7.4 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3759) DUF3759 PF12585.8 ORZ03646.1 - 9.5e-35 118.5 6.5 1.1e-34 118.3 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2939 PF11159.8 ORZ03646.1 - 0.041 14.3 0.0 0.074 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DUF3759 PF12585.8 ORZ03647.1 - 8e-35 118.8 7.3 9.1e-35 118.6 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2939 PF11159.8 ORZ03647.1 - 0.051 14.0 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Bacteriocin_II PF01721.18 ORZ03647.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Class II bacteriocin DUF3759 PF12585.8 ORZ03648.1 - 4e-33 113.3 7.2 5.1e-33 113.0 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2939 PF11159.8 ORZ03648.1 - 0.017 15.5 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) WRKY PF03106.15 ORZ03649.1 - 5e-10 39.4 2.5 5e-10 39.4 2.5 2.5 3 0 0 3 3 3 1 WRKY DNA -binding domain DEAD PF00270.29 ORZ03650.1 - 3.1e-46 157.4 0.0 5.3e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ03650.1 - 1.3e-29 102.7 0.1 2.4e-28 98.7 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.14 ORZ03650.1 - 0.087 12.8 0.9 14 5.6 0.2 2.7 2 0 0 2 2 2 0 Flavivirus DEAD domain COX7a PF02238.15 ORZ03651.1 - 1.3e-17 64.0 0.1 1.4e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII vATP-synt_E PF01991.18 ORZ03652.1 - 7.3e-43 146.3 13.6 9.1e-43 146.0 13.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RapH_N PF18801.1 ORZ03652.1 - 0.63 10.2 4.3 1.5 9.0 0.9 2.8 2 2 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF3365 PF11845.8 ORZ03652.1 - 2.8 8.2 6.4 2.1 8.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) MBOAT_2 PF13813.6 ORZ03653.1 - 2.5e-18 66.1 1.2 2.5e-18 66.1 1.2 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Kelch_4 PF13418.6 ORZ03654.1 - 2.2e-15 56.4 0.3 0.00017 21.5 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORZ03654.1 - 9e-15 54.3 0.1 0.00058 19.8 0.2 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 ORZ03654.1 - 3.5e-14 52.7 0.8 7.9e-07 29.2 0.0 5.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORZ03654.1 - 9e-13 47.6 0.2 0.0006 19.7 0.1 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 ORZ03654.1 - 1.5e-12 47.3 0.5 0.0074 16.5 0.1 4.7 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 ORZ03654.1 - 2.7e-12 46.9 0.3 5e-12 46.0 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 ORZ03654.1 - 1.2e-08 34.4 0.5 0.34 10.5 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Peptidase_M48 PF01435.18 ORZ03655.1 - 1.2e-37 129.7 0.0 1.8e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 SWIB PF02201.18 ORZ03656.1 - 1.6e-23 82.3 0.0 2.8e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 ORZ03656.1 - 2.7e-11 43.2 0.4 5.1e-11 42.3 0.4 1.4 1 0 0 1 1 1 1 DEK C terminal domain Nop53 PF07767.11 ORZ03656.1 - 0.0051 16.3 9.5 0.0066 15.9 9.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) TonB_N PF16031.5 ORZ03656.1 - 0.0055 17.2 10.7 0.0086 16.6 10.7 1.3 1 0 0 1 1 1 1 TonB polyproline region CDC45 PF02724.14 ORZ03656.1 - 0.006 14.9 4.3 0.0059 15.0 4.3 1.0 1 0 0 1 1 1 1 CDC45-like protein CPSF100_C PF13299.6 ORZ03656.1 - 0.045 13.9 2.6 0.055 13.6 2.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SPATIAL PF15256.6 ORZ03656.1 - 0.35 11.2 4.8 0.53 10.6 4.8 1.3 1 0 0 1 1 1 0 SPATIAL RP-C_C PF11800.8 ORZ03656.1 - 0.37 10.9 3.7 0.46 10.6 3.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Glycoprotein_G PF00802.19 ORZ03656.1 - 0.38 10.1 12.5 0.068 12.5 8.9 1.5 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G DUF3408 PF11888.8 ORZ03656.1 - 1.1 9.4 9.8 2.3 8.4 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) YqfQ PF14181.6 ORZ03656.1 - 1.3 9.2 10.7 2 8.6 10.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein Coilin_N PF15862.5 ORZ03656.1 - 3.6 7.4 11.1 5.4 6.8 9.1 2.1 1 1 1 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 ORZ03656.1 - 4.4 6.0 4.0 4.7 5.9 4.0 1.1 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.31 ORZ03657.1 - 0.0063 16.7 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Transp_cyt_pur PF02133.15 ORZ03658.1 - 1.1e-30 106.8 34.3 1.3e-30 106.6 34.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Hid1 PF12722.7 ORZ03659.1 - 2.5e-249 829.7 0.0 2.9e-249 829.5 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 ORZ03659.1 - 3.3e-132 442.1 0.1 4.1e-132 441.7 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SUIM_assoc PF16619.5 ORZ03659.1 - 0.22 11.6 11.0 0.039 14.0 2.9 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DASH_Spc19 PF08287.11 ORZ03659.1 - 0.35 10.8 3.8 9.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Spc19 Roughex PF06020.11 ORZ03659.1 - 2.8 7.0 4.8 4.9 6.1 4.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SRP-alpha_N PF04086.13 ORZ03659.1 - 6.4 6.6 9.1 12 5.8 9.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Homeodomain PF00046.29 ORZ03660.1 - 1.2e-14 53.8 0.3 1.2e-14 53.8 0.3 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORZ03660.1 - 0.03 14.2 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain Spt20 PF12090.8 ORZ03660.1 - 6.1 6.4 24.4 0.24 11.0 15.2 2.2 2 0 0 2 2 2 0 Spt20 family Lipase_3 PF01764.25 ORZ03661.1 - 5.1e-20 71.8 0.0 1.5e-19 70.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 ORZ03661.1 - 0.0018 17.8 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORZ03661.1 - 0.0034 18.0 0.0 0.017 15.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORZ03661.1 - 0.041 13.4 0.1 0.75 9.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ORZ03661.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ORZ03661.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORZ03661.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORZ03661.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain TFIIIC_sub6 PF10419.9 ORZ03662.1 - 3.6e-11 42.8 0.1 5e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain AMP-binding PF00501.28 ORZ03663.1 - 5.2e-92 308.6 0.1 6.3e-92 308.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORZ03663.1 - 2.5e-23 82.8 0.3 9.7e-23 81.0 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF5437 PF17505.2 ORZ03663.1 - 0.26 11.3 1.5 3.7 7.7 1.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5437) FAD_binding_3 PF01494.19 ORZ03664.1 - 3.3e-28 98.9 0.0 5.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORZ03664.1 - 3e-06 27.4 0.0 0.00028 20.9 0.0 2.5 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.6 ORZ03664.1 - 3.7e-05 23.1 0.2 0.00031 20.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORZ03664.1 - 7.6e-05 22.9 1.9 0.0006 20.0 0.6 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORZ03664.1 - 0.00021 20.5 0.0 0.00033 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORZ03664.1 - 0.0007 18.9 0.3 0.0013 18.1 0.3 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORZ03664.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORZ03664.1 - 0.0022 16.8 0.3 0.0022 16.8 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ORZ03664.1 - 0.0024 17.2 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORZ03664.1 - 0.013 14.6 0.1 0.035 13.2 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ORZ03664.1 - 0.013 14.8 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 ORZ03664.1 - 0.074 12.4 0.5 0.18 11.2 0.5 1.5 1 0 0 1 1 1 0 ThiF family FAD_oxidored PF12831.7 ORZ03664.1 - 0.5 9.6 3.9 0.12 11.6 0.4 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ras PF00071.22 ORZ03665.1 - 9.5e-67 223.6 1.1 1.1e-66 223.4 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ03665.1 - 9.9e-37 125.8 0.2 1.8e-36 125.0 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ03665.1 - 6e-18 64.9 0.3 7.3e-18 64.6 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORZ03665.1 - 1.9e-06 27.5 1.0 4e-06 26.5 0.6 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORZ03665.1 - 4.5e-06 26.7 1.3 0.05 13.5 0.3 2.4 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 ORZ03665.1 - 8.5e-06 25.3 0.2 1.3e-05 24.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORZ03665.1 - 1.6e-05 24.4 0.0 2.6e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORZ03665.1 - 1.8e-05 24.8 0.1 4.1e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 ORZ03665.1 - 0.0017 18.8 0.1 0.17 12.3 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 ORZ03665.1 - 0.0022 17.4 0.4 0.17 11.1 0.0 2.2 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 ORZ03665.1 - 0.0022 17.5 0.2 0.014 15.0 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 ORZ03665.1 - 0.003 18.0 0.0 0.0046 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 ORZ03665.1 - 0.0077 16.0 0.8 0.014 15.2 0.2 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 ORZ03665.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ORZ03665.1 - 0.032 13.7 0.2 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 ORZ03665.1 - 0.039 14.5 0.3 0.1 13.1 0.3 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ORZ03665.1 - 0.045 14.0 0.0 0.061 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORZ03665.1 - 0.047 13.4 0.1 1.4 8.7 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ORZ03665.1 - 0.054 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORZ03665.1 - 0.072 12.5 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 ORZ03665.1 - 0.17 11.5 0.3 1.1 8.8 0.3 2.2 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 ORZ03666.1 - 0.03 15.2 0.6 15 6.7 0.2 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat MutS_V PF00488.21 ORZ03667.1 - 5e-78 261.5 0.1 1.1e-77 260.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORZ03667.1 - 2.1e-33 116.1 12.0 7.5e-33 114.4 12.0 2.0 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORZ03667.1 - 2.2e-25 89.1 0.0 1.3e-24 86.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 ORZ03667.1 - 9.4e-10 38.9 0.0 3.2e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORZ03667.1 - 0.00014 22.1 0.5 0.00036 20.8 0.5 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 ORZ03667.1 - 0.11 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORZ03667.1 - 0.2 12.1 0.8 19 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fe-S_biosyn PF01521.20 ORZ03668.1 - 7.6e-19 67.9 0.1 1e-18 67.5 0.1 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis KH_1 PF00013.29 ORZ03669.1 - 1.6e-08 34.2 0.0 6.5e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 KH domain FMO-like PF00743.19 ORZ03670.1 - 5.3e-49 167.0 0.0 3.3e-26 91.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORZ03670.1 - 2.6e-16 59.8 0.0 2.1e-09 37.1 0.0 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORZ03670.1 - 1.6e-10 40.7 0.0 2.7e-09 36.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORZ03670.1 - 1.7e-06 28.2 0.0 4.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORZ03670.1 - 6.6e-06 26.2 1.2 7.1e-05 22.8 0.2 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORZ03670.1 - 4.9e-05 22.6 0.1 0.0039 16.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 ORZ03670.1 - 0.00016 21.1 0.5 0.5 9.6 0.0 3.6 3 1 1 4 4 4 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ORZ03670.1 - 0.00016 22.1 0.2 0.02 15.4 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORZ03670.1 - 0.00018 21.0 0.4 0.00057 19.4 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORZ03670.1 - 0.00025 19.9 0.3 0.00041 19.2 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ORZ03670.1 - 0.00049 19.4 0.1 0.0018 17.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORZ03670.1 - 0.0028 16.8 0.3 0.005 16.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORZ03670.1 - 0.014 15.0 0.2 0.63 9.6 0.2 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORZ03670.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORZ03670.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORZ03670.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A COG4 PF08318.12 ORZ03671.1 - 3.5e-90 302.5 0.0 7.4e-90 301.4 0.0 1.6 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 ORZ03671.1 - 2.5e-05 23.4 2.2 6.1e-05 22.1 2.2 1.6 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Vps53_N PF04100.12 ORZ03671.1 - 0.00065 18.8 7.2 0.0014 17.7 7.2 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF4164 PF13747.6 ORZ03671.1 - 0.0046 17.2 1.1 0.0046 17.2 1.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4164) FapA PF03961.13 ORZ03671.1 - 0.04 12.5 0.9 0.067 11.8 0.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 ORZ03671.1 - 0.17 11.0 3.1 0.32 10.0 3.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med2 PF11214.8 ORZ03671.1 - 1.1 9.4 6.4 1.9 8.7 1.8 2.8 2 0 0 2 2 2 0 Mediator complex subunit 2 zf-C4H2 PF10146.9 ORZ03671.1 - 1.5 9.1 5.3 6.2 7.1 3.7 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein Syntaxin_2 PF14523.6 ORZ03671.1 - 1.6 9.1 9.8 87 3.6 7.6 3.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF4600 PF15372.6 ORZ03671.1 - 2.2 8.7 7.4 2.6 8.5 1.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) GAS PF13851.6 ORZ03671.1 - 3.8 6.8 11.2 0.27 10.6 5.2 2.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Ysc84 PF04366.12 ORZ03672.1 - 5.1e-44 149.1 0.5 8.4e-44 148.4 0.5 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORZ03672.1 - 6.8e-15 54.4 0.2 1.5e-14 53.3 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORZ03672.1 - 4.1e-13 49.0 0.0 7.4e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORZ03672.1 - 1.7e-09 37.2 0.0 3.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.13 ORZ03672.1 - 0.039 14.6 13.3 0.079 13.6 13.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3104 PF11302.8 ORZ03672.1 - 0.16 11.8 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Glyco_transf_15 PF01793.16 ORZ03673.1 - 5.5e-120 400.5 13.9 6.7e-120 400.2 13.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DAPDH_C PF16654.5 ORZ03673.1 - 0.0023 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Diaminopimelic acid dehydrogenase C-terminal domain DUF3405 PF11885.8 ORZ03673.1 - 0.059 12.0 4.3 0.076 11.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Polysacc_deac_1 PF01522.21 ORZ03674.1 - 3.8e-27 94.6 0.1 7.1e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Vesiculo_matrix PF06326.12 ORZ03674.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Vesiculovirus matrix protein TGT PF01702.18 ORZ03676.1 - 9.7e-65 219.0 0.0 1.2e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Amidohydro_2 PF04909.14 ORZ03677.1 - 2.1e-09 37.6 0.0 4.6e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 ORZ03677.1 - 1.4e-05 24.6 0.1 2.3e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family Oxidored_FMN PF00724.20 ORZ03678.1 - 2.5e-58 198.0 0.0 3.1e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Metallophos PF00149.28 ORZ03679.1 - 1.7e-37 130.0 0.2 2.6e-37 129.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 ORZ03679.1 - 0.058 12.7 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) DUF1647 PF07801.11 ORZ03679.1 - 0.13 12.0 1.6 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) VP9 PF09625.10 ORZ03679.1 - 0.14 12.3 0.0 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 VP9 protein Thioredoxin PF00085.20 ORZ03680.1 - 3.7e-33 113.6 0.0 1.5e-26 92.3 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_8 PF13905.6 ORZ03680.1 - 8.9e-08 32.4 0.1 1.7 9.0 0.0 4.5 3 2 1 4 4 4 3 Thioredoxin-like Thioredoxin_2 PF13098.6 ORZ03680.1 - 6.2e-06 26.6 0.5 0.12 12.8 0.1 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ORZ03680.1 - 1e-05 25.0 0.0 0.021 14.2 0.0 3.0 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family TraF PF13728.6 ORZ03680.1 - 0.0031 17.4 5.2 3.6 7.3 0.0 4.3 2 1 1 5 5 5 2 F plasmid transfer operon protein AhpC-TSA PF00578.21 ORZ03680.1 - 0.018 15.0 0.1 0.62 10.0 0.0 2.6 3 0 0 3 3 3 0 AhpC/TSA family QSOX_Trx1 PF18108.1 ORZ03680.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 QSOX Trx-like domain Sds3 PF08598.11 ORZ03681.1 - 1.5e-18 67.6 3.5 1.5e-18 67.6 3.5 2.2 2 0 0 2 2 2 1 Sds3-like BSP_II PF05432.11 ORZ03681.1 - 2.3 7.9 29.0 4.2 7.0 29.0 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TLD PF07534.16 ORZ03682.1 - 2.2e-23 83.0 0.0 2.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 TLD Myb_DNA-binding PF00249.31 ORZ03683.1 - 0.0028 17.8 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORZ03683.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain SR-25 PF10500.9 ORZ03683.1 - 0.54 9.8 4.8 0.84 9.2 4.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 ORZ03684.1 - 1.2e-70 238.0 0.3 1.2e-70 238.0 0.3 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03684.1 - 2e-50 171.5 0.3 2e-50 171.5 0.3 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 ORZ03684.1 - 5e-20 71.6 0.0 1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORZ03684.1 - 7.3e-13 48.9 0.3 1.6e-12 47.9 0.3 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORZ03684.1 - 2.8e-06 26.9 0.1 5.9e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Kinase-like PH_11 PF15413.6 ORZ03684.1 - 0.00059 20.2 3.3 0.039 14.4 0.5 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 ORZ03684.1 - 0.00061 18.7 12.7 0.0035 16.2 12.7 1.9 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORZ03684.1 - 0.0037 16.2 2.5 0.013 14.4 2.5 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORZ03684.1 - 0.33 10.8 4.0 0.74 9.7 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mpp10 PF04006.12 ORZ03684.1 - 2.4 6.5 16.2 3.7 5.9 16.2 1.2 1 0 0 1 1 1 0 Mpp10 protein SPG4 PF17325.2 ORZ03684.1 - 2.9 9.0 6.0 9 7.4 6.0 1.8 1 0 0 1 1 1 0 Stationary phase protein 4 CDC45 PF02724.14 ORZ03684.1 - 4.7 5.4 10.2 6.9 4.8 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 ORZ03685.1 - 3e-43 148.3 0.0 3.6e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeoB_C PF07664.12 ORZ03685.1 - 0.13 12.0 0.1 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus NAD_binding_6 PF08030.12 ORZ03686.1 - 2.8e-13 50.3 0.0 2e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORZ03686.1 - 7.3e-13 48.7 11.1 7.3e-13 48.7 11.1 3.1 3 2 1 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 ORZ03686.1 - 0.00022 21.8 0.0 0.00042 20.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Josephin PF02099.17 ORZ03689.1 - 1.3e-28 100.1 2.0 2e-27 96.3 2.0 2.4 1 1 0 1 1 1 1 Josephin UIM PF02809.20 ORZ03689.1 - 0.00041 20.1 1.7 0.0019 18.0 1.7 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif AAA PF00004.29 ORZ03690.1 - 6.2e-50 169.0 0.0 9.6e-37 126.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORZ03690.1 - 1.7e-17 62.9 2.6 6.4e-11 41.9 0.5 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORZ03690.1 - 2.7e-12 47.4 0.5 0.00054 20.4 0.0 4.4 2 2 1 3 3 3 2 AAA ATPase domain DUF815 PF05673.13 ORZ03690.1 - 3.1e-11 42.9 0.0 2.2e-05 23.8 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORZ03690.1 - 9.8e-10 38.8 0.3 0.0065 16.8 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORZ03690.1 - 3.3e-08 33.2 0.0 0.0058 16.2 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 ORZ03690.1 - 2.9e-07 30.5 1.4 0.1 12.5 0.0 3.5 2 1 1 3 3 3 2 NACHT domain RNA_helicase PF00910.22 ORZ03690.1 - 6.1e-07 29.8 0.0 0.041 14.3 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 ORZ03690.1 - 6.8e-07 29.4 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 ORZ03690.1 - 1.4e-06 28.2 0.1 0.0047 16.7 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 ORZ03690.1 - 1.4e-06 28.3 0.4 0.0024 17.9 0.0 3.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORZ03690.1 - 1.9e-06 28.4 0.0 0.053 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 ORZ03690.1 - 2.4e-06 27.4 0.0 4e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORZ03690.1 - 2.5e-06 27.7 2.4 0.0041 17.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORZ03690.1 - 8.4e-06 25.2 0.5 0.17 11.1 0.1 3.6 3 1 1 4 4 4 2 Zeta toxin Sigma54_activat PF00158.26 ORZ03690.1 - 2.3e-05 24.2 0.0 0.067 12.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 ORZ03690.1 - 3e-05 23.5 0.1 0.0032 16.9 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ORZ03690.1 - 3.2e-05 24.2 3.1 0.32 11.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 ORZ03690.1 - 3.7e-05 23.7 0.0 0.68 9.8 0.0 3.0 2 1 0 3 3 3 2 Rad17 P-loop domain AAA_25 PF13481.6 ORZ03690.1 - 4.8e-05 23.0 3.2 0.18 11.3 0.2 4.2 2 2 1 4 4 4 1 AAA domain TIP49 PF06068.13 ORZ03690.1 - 6.2e-05 22.4 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 ORZ03690.1 - 9.5e-05 22.6 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 ORZ03690.1 - 0.00016 21.7 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORZ03690.1 - 0.00016 21.4 0.7 0.037 13.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORZ03690.1 - 0.00026 21.0 0.2 7.8 6.4 0.0 3.3 2 1 0 3 3 3 0 NTPase AAA_29 PF13555.6 ORZ03690.1 - 0.00041 20.0 0.1 0.34 10.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain TniB PF05621.11 ORZ03690.1 - 0.00069 19.1 0.0 1.8 7.9 0.0 2.9 2 1 1 3 3 3 2 Bacterial TniB protein ATPase PF06745.13 ORZ03690.1 - 0.00089 18.7 0.0 0.38 10.1 0.0 2.6 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 ORZ03690.1 - 0.0013 19.3 0.3 0.96 10.0 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 ORZ03690.1 - 0.0014 18.4 0.6 0.61 9.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ORZ03690.1 - 0.004 16.4 0.9 2.1 7.5 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 ORZ03690.1 - 0.0044 16.9 0.0 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_3 PF07726.11 ORZ03690.1 - 0.0052 16.7 0.0 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORZ03690.1 - 0.0061 17.0 0.0 0.41 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORZ03690.1 - 0.0075 16.6 0.5 1.4 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORZ03690.1 - 0.0088 16.0 0.0 0.93 9.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase PhoH PF02562.16 ORZ03690.1 - 0.01 15.3 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 ORZ03690.1 - 0.012 14.6 0.3 2.8 6.9 0.5 2.7 2 1 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.9 ORZ03690.1 - 0.018 14.2 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Guanylate_kin PF00625.21 ORZ03690.1 - 0.019 14.6 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase KAP_NTPase PF07693.14 ORZ03690.1 - 0.023 14.0 0.5 6 6.0 0.9 3.0 2 1 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 ORZ03690.1 - 0.028 14.3 0.0 1.4 8.8 0.0 2.7 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea IPT PF01745.16 ORZ03690.1 - 0.029 13.8 0.3 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.12 ORZ03690.1 - 0.035 13.7 0.2 27 4.3 0.0 3.6 3 1 1 4 4 4 0 Zonular occludens toxin (Zot) Parvo_NS1 PF01057.17 ORZ03690.1 - 0.042 12.9 0.2 0.089 11.9 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 Roc PF08477.13 ORZ03690.1 - 0.049 13.9 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 ORZ03690.1 - 0.062 12.9 0.7 2.1 7.9 0.1 2.8 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.19 ORZ03690.1 - 0.076 12.6 0.2 2.3 7.8 0.0 2.5 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 ORZ03690.1 - 0.077 12.1 0.0 8.9 5.3 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_11 PF13086.6 ORZ03690.1 - 0.077 12.8 0.5 1.2 8.8 0.2 2.4 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 ORZ03690.1 - 0.085 13.0 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 ORZ03690.1 - 0.099 11.8 0.5 1.1 8.3 0.0 2.7 3 1 0 3 3 3 0 NB-ARC domain MMR_HSR1 PF01926.23 ORZ03690.1 - 0.14 12.2 0.0 18 5.4 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AIG1 PF04548.16 ORZ03690.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_23 PF13476.6 ORZ03690.1 - 0.22 12.0 0.2 17 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Barwin PF00967.17 ORZ03692.1 - 0.0096 15.8 0.1 0.033 14.0 0.1 1.9 1 0 0 1 1 1 1 Barwin family DUF4228 PF14009.6 ORZ03693.1 - 0.013 15.9 0.2 0.013 15.9 0.2 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) E1-E2_ATPase PF00122.20 ORZ03693.1 - 0.89 9.0 4.0 0.96 8.9 0.1 2.6 3 0 0 3 3 3 0 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORZ03694.1 - 2.5e-08 33.8 13.2 3.2e-08 33.5 13.2 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Integrin_b_cyt PF08725.11 ORZ03694.1 - 0.14 11.9 0.2 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain DUF1461 PF07314.11 ORZ03694.1 - 0.28 11.0 6.0 0.6 10.0 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) RXT2_N PF08595.11 ORZ03695.1 - 1.7 8.7 4.3 2.4 8.2 4.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_RNA_Pol_19 PF05320.12 ORZ03695.1 - 4.4 7.2 7.2 5.9 6.8 7.2 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PBP1_TM PF14812.6 ORZ03695.1 - 5.1 7.5 9.2 7.7 7.0 9.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-CCCH PF00642.24 ORZ03696.1 - 1.8e-21 75.5 14.7 1.3e-10 40.9 4.2 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORZ03696.1 - 1.5e-13 50.3 16.4 1.1e-07 31.7 5.9 2.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORZ03696.1 - 1e-10 41.1 13.6 1.2e-07 31.4 3.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORZ03696.1 - 2.6e-07 30.8 8.9 0.00023 21.5 1.7 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORZ03696.1 - 0.011 16.5 10.6 0.37 11.5 1.7 2.1 1 1 1 2 2 2 0 Torus domain zf-CCHH PF10283.9 ORZ03696.1 - 2 8.4 8.9 3 7.9 4.1 2.6 2 1 0 2 2 2 0 PBZ domain oligo_HPY PF08352.12 ORZ03696.1 - 2.7 8.6 8.4 7.4 7.2 0.8 2.2 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region MRI PF15325.6 ORZ03697.1 - 0.075 14.1 0.8 0.75 10.9 0.1 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection Med15_fungi PF05397.12 ORZ03699.1 - 1.2e-24 86.7 0.6 1.2e-24 86.7 0.6 4.4 5 0 0 5 5 5 1 Mediator complex subunit 15 SUIM_assoc PF16619.5 ORZ03699.1 - 0.0075 16.3 0.7 0.0075 16.3 0.7 8.7 5 3 2 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 Lsr2 PF11774.8 ORZ03699.1 - 1 9.5 16.9 0.2 11.8 3.3 3.5 3 0 0 3 3 3 0 Lsr2 Rtf2 PF04641.12 ORZ03699.1 - 2.4 7.5 18.3 0.018 14.4 3.1 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger KIX_2 PF16987.5 ORZ03700.1 - 2.7e-06 27.3 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 KIX domain PH_9 PF15410.6 ORZ03701.1 - 3.6e-05 24.1 0.1 0.00051 20.4 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORZ03701.1 - 0.001 19.6 0.0 0.002 18.6 0.0 1.6 1 0 0 1 1 1 1 PH domain tRNA-synt_1c PF00749.21 ORZ03702.1 - 1.1e-108 362.9 0.0 1.6e-108 362.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 ORZ03702.1 - 3.3e-55 186.5 0.1 5.7e-55 185.7 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 ORZ03702.1 - 1.2e-37 129.4 0.0 5.3e-37 127.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 ORZ03702.1 - 2.3e-13 50.9 6.1 7.7e-13 49.2 6.1 1.9 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ham1p_like PF01725.16 ORZ03703.1 - 1.9e-60 204.0 0.0 2.1e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HLH PF00010.26 ORZ03705.1 - 6.7e-11 42.0 0.5 1.5e-10 40.8 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HSP70 PF00012.20 ORZ03706.1 - 2.6e-09 35.8 0.0 1.7e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORZ03706.1 - 3.2e-05 22.9 0.0 0.0015 17.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Peptidase_M22 PF00814.25 ORZ03706.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Adaptin_N PF01602.20 ORZ03708.1 - 7.7e-43 146.8 0.4 2.1e-42 145.4 0.2 1.8 2 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 ORZ03708.1 - 9.9e-08 32.2 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORZ03708.1 - 0.0094 16.3 0.7 0.027 14.8 0.2 2.1 2 0 0 2 2 2 1 HEAT repeats ParcG PF10274.9 ORZ03708.1 - 0.094 12.8 0.9 0.76 9.9 0.0 2.5 2 1 0 2 2 2 0 Parkin co-regulated protein HEAT_EZ PF13513.6 ORZ03708.1 - 0.21 12.1 0.4 16 6.1 0.1 3.1 3 0 0 3 3 3 0 HEAT-like repeat DUF4499 PF14934.6 ORZ03708.1 - 0.29 11.5 1.3 1.2 9.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4499) SRF-TF PF00319.18 ORZ03709.1 - 1.8e-21 75.3 0.1 2.4e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HSF_DNA-bind PF00447.17 ORZ03710.1 - 3.8e-29 101.1 0.6 7.1e-29 100.3 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 ORZ03710.1 - 4.2e-27 94.5 0.2 9.2e-27 93.4 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HSL_N PF06350.12 ORZ03710.1 - 0.059 12.3 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus MSP1_C PF07462.11 ORZ03710.1 - 0.35 9.5 1.5 0.53 8.9 0.9 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Dehydrin PF00257.19 ORZ03710.1 - 1.1 9.7 9.6 0.16 12.5 4.6 2.1 2 0 0 2 2 2 0 Dehydrin PRIMA1 PF16101.5 ORZ03710.1 - 2 8.5 6.6 4.2 7.4 6.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3439 PF11921.8 ORZ03710.1 - 5.8 6.9 13.3 2.5 8.1 10.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PB1 PF00564.24 ORZ03711.1 - 4.2e-10 39.4 0.1 8.2e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DUF4482 PF14818.6 ORZ03711.1 - 0.0091 16.9 3.2 0.018 15.9 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) DUF1510 PF07423.11 ORZ03711.1 - 0.029 14.5 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) SR-25 PF10500.9 ORZ03711.1 - 0.36 10.4 18.0 0.63 9.6 18.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDRGK PF09756.9 ORZ03711.1 - 0.62 9.6 7.7 0.94 9.0 7.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4407 PF14362.6 ORZ03711.1 - 0.64 9.3 1.9 0.97 8.7 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sporozoite_P67 PF05642.11 ORZ03711.1 - 2.3 6.2 6.5 4.4 5.3 6.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rrn6 PF10214.9 ORZ03711.1 - 2.8 6.3 9.4 4.3 5.7 9.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF755 PF05501.11 ORZ03711.1 - 4 7.7 17.3 9.8 6.5 17.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Glyco_hydro_46 PF01374.18 ORZ03712.1 - 7.4e-34 117.2 0.2 9.8e-34 116.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_4 PF02056.16 ORZ03712.1 - 0.12 11.9 0.1 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Aldo_ket_red PF00248.21 ORZ03713.1 - 7.1e-42 143.6 0.0 8.5e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family KilA-N PF04383.13 ORZ03714.1 - 0.004 17.0 0.0 0.01 15.6 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain DUF1505 PF07403.11 ORZ03715.1 - 0.0037 17.4 0.1 0.0042 17.2 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1505) Defensin_big PF14862.6 ORZ03715.1 - 0.0081 16.4 0.3 0.0081 16.4 0.3 1.9 2 0 0 2 2 2 1 Big defensin Inhibitor_I53 PF11714.8 ORZ03715.1 - 0.012 15.8 0.1 0.013 15.7 0.1 1.3 1 1 0 1 1 1 0 Thrombin inhibitor Madanin Gly-zipper_YMGG PF13441.6 ORZ03716.1 - 0.01 15.5 7.6 0.022 14.5 7.6 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 ORZ03716.1 - 0.015 15.2 7.2 0.026 14.4 7.2 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain PTP_tm PF18861.1 ORZ03716.1 - 0.015 15.3 2.7 0.025 14.6 2.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Kelch_2 PF07646.15 ORZ03716.1 - 0.025 14.6 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 Kelch motif CD34_antigen PF06365.12 ORZ03716.1 - 0.042 13.4 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2613 PF11021.8 ORZ03716.1 - 0.056 13.6 0.2 0.056 13.6 0.2 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2613) SKG6 PF08693.10 ORZ03716.1 - 0.077 12.4 2.7 0.13 11.7 2.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 ORZ03716.1 - 0.084 11.7 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 ORZ03716.1 - 0.09 13.7 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_2 PF07646.15 ORZ03717.1 - 4.4e-10 39.1 2.5 1.8e-07 30.9 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 ORZ03717.1 - 4.4e-08 33.1 17.4 0.00083 19.6 1.2 4.7 3 2 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 ORZ03717.1 - 1.8e-07 31.0 6.4 0.0097 15.9 0.4 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 ORZ03717.1 - 1.8e-06 27.4 10.9 0.0013 18.3 0.3 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 ORZ03717.1 - 6e-05 23.0 16.5 0.069 13.2 0.3 5.2 5 2 1 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 ORZ03717.1 - 0.043 14.1 2.0 0.043 14.1 2.0 4.1 4 2 0 4 4 4 0 Galactose oxidase, central domain GldM_C PF12080.8 ORZ03717.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 GldM C-terminal domain Kelch_4 PF13418.6 ORZ03718.1 - 8e-11 41.8 7.4 0.0019 18.2 0.1 4.4 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 ORZ03718.1 - 6.8e-10 38.9 10.4 0.026 14.8 0.1 4.6 4 1 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 ORZ03718.1 - 1.6e-08 34.3 4.9 0.084 12.9 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 ORZ03718.1 - 1.7e-07 31.3 2.4 0.00063 20.0 0.0 3.0 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORZ03718.1 - 1.4e-05 24.9 8.1 0.25 11.4 0.0 4.7 4 2 0 4 4 4 2 Kelch motif PTP_tm PF18861.1 ORZ03718.1 - 0.0011 19.1 1.6 0.0017 18.4 1.6 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J CYYR1 PF10873.8 ORZ03718.1 - 0.047 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Kelch_1 PF01344.25 ORZ03718.1 - 1.2 8.7 5.9 3.7 7.2 0.0 3.7 4 0 0 4 4 4 0 Kelch motif CYYR1 PF10873.8 ORZ03720.1 - 1.2e-05 25.8 1.0 2e-05 25.1 1.0 1.2 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Kelch_4 PF13418.6 ORZ03720.1 - 0.00011 22.2 0.1 0.21 11.6 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Podoplanin PF05808.11 ORZ03720.1 - 0.00018 21.7 0.1 0.00028 21.0 0.1 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 ORZ03720.1 - 0.0016 17.8 7.1 0.0035 16.7 7.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 ORZ03720.1 - 0.0044 15.9 3.4 0.0062 15.4 3.4 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF2613 PF11021.8 ORZ03720.1 - 0.0058 16.7 2.4 0.014 15.5 2.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) DUF4448 PF14610.6 ORZ03720.1 - 0.006 16.4 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Kelch_5 PF13854.6 ORZ03720.1 - 0.019 15.0 4.9 0.029 14.3 0.1 3.0 3 1 1 4 4 4 0 Kelch motif Kelch_6 PF13964.6 ORZ03720.1 - 0.022 15.0 0.1 7.9 6.9 0.2 2.7 2 0 0 2 2 2 0 Kelch motif DAG1 PF05454.11 ORZ03720.1 - 0.032 13.6 0.8 0.066 12.6 0.0 1.8 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4690 PF15756.5 ORZ03720.1 - 0.033 14.8 0.1 0.081 13.5 0.0 1.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 ORZ03720.1 - 0.048 14.5 0.0 0.081 13.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 ORZ03720.1 - 0.059 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 ORZ03720.1 - 0.082 12.8 1.5 0.15 12.0 1.5 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4514 PF14986.6 ORZ03720.1 - 0.13 12.2 1.6 0.25 11.3 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Kelch_6 PF13964.6 ORZ03721.1 - 2.7e-10 40.1 6.0 0.17 12.2 0.1 4.7 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 ORZ03721.1 - 3.3e-08 33.4 2.7 0.11 12.5 0.1 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORZ03721.1 - 3.4e-07 30.1 2.5 0.018 15.0 0.6 3.4 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 ORZ03721.1 - 2.2e-06 27.1 3.5 0.014 15.0 0.5 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 ORZ03721.1 - 0.043 14.1 13.3 0.2 12.0 1.2 4.9 5 1 0 5 5 5 0 Galactose oxidase, central domain PD40 PF07676.12 ORZ03721.1 - 0.085 12.8 0.5 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat FAD_binding_3 PF01494.19 ORZ03723.1 - 1.4e-68 231.7 0.2 2e-68 231.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORZ03723.1 - 0.00027 21.1 0.0 0.00069 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phe_hydrox_dim PF07976.12 ORZ03723.1 - 0.00028 20.9 0.0 0.00063 19.8 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 ORZ03723.1 - 0.002 17.4 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ORZ03723.1 - 0.011 15.0 0.7 0.63 9.2 0.1 2.7 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORZ03723.1 - 0.018 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 ORZ03723.1 - 0.039 13.3 0.0 0.084 12.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ORZ03723.1 - 0.042 13.7 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HSF_DNA-bind PF00447.17 ORZ03725.1 - 2e-13 50.7 0.1 2e-13 50.7 0.1 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding SelP_N PF04592.14 ORZ03725.1 - 0.032 13.6 16.6 0.047 13.1 16.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 ORZ03725.1 - 9.8 5.3 6.8 16 4.6 6.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter LSM PF01423.22 ORZ03726.1 - 4.8e-18 64.6 0.3 6.3e-18 64.2 0.3 1.2 1 0 0 1 1 1 1 LSM domain CAP_GLY PF01302.25 ORZ03727.1 - 7.7e-21 73.9 0.1 1.2e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Menin PF05053.13 ORZ03727.1 - 2.6 6.3 10.1 0.065 11.6 0.4 2.0 2 0 0 2 2 2 0 Menin Auxin_repressed PF05564.12 ORZ03727.1 - 4.6 8.0 13.1 0.65 10.7 4.6 2.8 2 2 0 2 2 2 0 Dormancy/auxin associated protein WD40 PF00400.32 ORZ03728.1 - 2.3e-26 91.5 8.9 5.9e-07 30.1 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03728.1 - 1.5e-13 50.8 0.0 0.00023 21.4 0.1 5.6 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORZ03728.1 - 7.7e-05 21.8 0.4 2.7 6.9 0.0 4.5 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORZ03728.1 - 0.00015 21.8 0.0 0.054 13.4 0.0 3.6 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 ORZ03728.1 - 0.00091 19.0 14.2 0.0038 17.0 0.2 3.8 4 0 0 4 4 4 2 HIRA B motif PD40 PF07676.12 ORZ03728.1 - 0.014 15.3 0.4 1.2 9.2 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 ORZ03728.1 - 0.049 11.6 0.0 2.4 6.0 0.0 2.5 1 1 1 2 2 2 0 IKI3 family Coatomer_WDAD PF04053.14 ORZ03728.1 - 0.061 12.4 0.0 1.9 7.4 0.0 2.7 2 1 0 2 2 2 0 Coatomer WD associated region Alpha-2-MRAP_C PF06401.11 ORZ03729.1 - 0.0085 16.1 1.5 0.011 15.7 1.5 1.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain PQ-loop PF04193.14 ORZ03730.1 - 1.8e-17 62.8 10.2 9e-14 51.0 1.5 3.3 4 0 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 ORZ03730.1 - 0.0061 17.4 5.7 0.096 13.5 1.0 2.7 2 1 0 2 2 2 2 ER lumen protein retaining receptor F-box PF00646.33 ORZ03731.1 - 0.016 15.1 0.3 0.041 13.8 0.0 1.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 ORZ03731.1 - 0.069 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like PRANC PF09372.10 ORZ03731.1 - 0.077 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 PRANC domain Xpo1 PF08389.12 ORZ03732.1 - 9e-38 129.7 0.6 1.5e-36 125.7 0.2 2.9 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 ORZ03732.1 - 3.1e-07 30.2 0.1 3.4e-05 23.7 0.0 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 ORZ03732.1 - 0.0027 17.8 0.0 1.1 9.7 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 ORZ03732.1 - 0.0047 17.3 0.0 0.26 11.7 0.0 3.6 5 0 0 5 5 5 1 HEAT repeats CsgA PF17334.2 ORZ03732.1 - 0.12 13.1 0.7 4.5 8.1 0.0 3.4 4 0 0 4 4 4 0 Minor curli fiber component A Sec1 PF00995.23 ORZ03733.1 - 6.1e-117 392.2 0.4 6.9e-117 392.1 0.4 1.0 1 0 0 1 1 1 1 Sec1 family XPC-binding PF09280.11 ORZ03733.1 - 0.11 12.2 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 XPC-binding domain Pkinase PF00069.25 ORZ03734.1 - 3.9e-75 252.6 0.3 5.1e-74 249.0 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03734.1 - 3.1e-33 115.2 0.0 2.7e-31 108.8 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03734.1 - 1.9e-08 34.0 1.1 4e-05 23.1 0.2 2.6 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 ORZ03734.1 - 3e-06 27.0 1.8 3e-06 27.0 1.8 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 ORZ03734.1 - 0.1 11.3 11.1 0.85 8.3 11.1 2.3 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORZ03734.1 - 0.35 10.7 8.2 0.55 10.1 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family UQ_con PF00179.26 ORZ03735.1 - 1.5e-43 147.8 0.0 1.7e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 ORZ03735.1 - 0.0041 16.8 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 ORZ03735.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Zn_clus PF00172.18 ORZ03736.1 - 9e-09 35.3 9.2 1e-08 35.1 9.2 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORZ03737.1 - 3.6e-36 124.6 1.0 1.7e-35 122.4 1.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 ORZ03739.1 - 1.2e-42 146.1 0.0 1.7e-23 83.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03739.1 - 1.7e-18 66.8 0.0 2.1e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03739.1 - 0.0027 17.1 0.0 0.77 9.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORZ03739.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORZ03739.1 - 0.023 14.3 0.0 0.062 12.9 0.0 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Sel1 PF08238.12 ORZ03740.1 - 9.9e-72 235.8 108.7 9.9e-06 26.1 0.3 26.9 27 0 0 27 27 27 22 Sel1 repeat TPR_11 PF13414.6 ORZ03740.1 - 0.003 17.2 25.7 2.2 8.0 0.1 8.8 8 0 0 8 8 8 3 TPR repeat TPR_6 PF13174.6 ORZ03740.1 - 0.11 13.2 42.6 0.21 12.3 0.1 13.5 17 1 1 18 18 18 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ03740.1 - 1.3 9.2 37.8 4 7.7 0.2 12.4 13 1 1 14 14 14 0 Tetratricopeptide repeat Podoplanin PF05808.11 ORZ03741.1 - 4.2e-06 27.0 1.9 7.1e-06 26.2 1.9 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 ORZ03741.1 - 0.048 13.1 1.5 0.23 10.9 1.5 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ndc1_Nup PF09531.10 ORZ03741.1 - 0.3 9.7 6.1 0.33 9.6 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bacteriocin_IIc PF10439.9 ORZ03741.1 - 6.8 6.9 12.9 14 5.9 0.6 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide NUDIX PF00293.28 ORZ03742.1 - 2.8e-16 59.8 0.1 3.7e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 ORZ03742.1 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4916) Sa_NUDIX PF18167.1 ORZ03742.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 SMODS-associated NUDIX domain GPI2 PF06432.11 ORZ03743.1 - 3e-95 318.9 15.2 3.4e-95 318.7 15.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2512 PF10710.9 ORZ03743.1 - 0.011 15.3 3.8 0.011 15.3 3.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2512) QueT PF06177.11 ORZ03743.1 - 8.8 6.7 15.3 0.86 10.0 8.9 2.4 2 1 0 2 2 2 0 QueT transporter DUF4451 PF14616.6 ORZ03744.1 - 2e-16 60.3 2.8 3.3e-16 59.6 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) WD40 PF00400.32 ORZ03746.1 - 3.4e-41 138.4 34.2 2.6e-06 28.0 1.5 7.5 8 0 0 8 8 7 7 WD domain, G-beta repeat Nup160 PF11715.8 ORZ03746.1 - 1.4e-13 50.3 3.9 0.0077 14.9 0.2 5.1 3 2 2 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORZ03746.1 - 2.9e-12 46.7 4.2 0.15 12.4 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ03746.1 - 1.1e-10 41.3 0.8 9.5e-05 21.9 0.0 3.0 1 1 2 3 3 3 3 WD40-like domain PQQ_2 PF13360.6 ORZ03746.1 - 4e-06 26.6 0.2 0.046 13.3 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.6 ORZ03746.1 - 1.9e-05 24.6 0.0 8.6 6.5 0.0 4.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 ORZ03746.1 - 0.0003 19.8 3.7 1.5 7.7 0.0 4.8 1 1 6 7 7 7 2 Partner and localizer of BRCA2 WD40 domain F-box-like PF12937.7 ORZ03746.1 - 0.00087 19.1 0.3 0.0018 18.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like DUF5046 PF16465.5 ORZ03746.1 - 0.0023 17.5 0.1 7.6 5.9 0.0 3.5 1 1 3 4 4 4 1 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 ORZ03746.1 - 0.0073 15.3 2.1 3.7 6.4 0.1 3.4 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 ORZ03746.1 - 0.021 15.3 0.9 11 6.6 0.0 4.2 3 1 1 4 4 3 0 PQQ-like domain DUF1258 PF06869.12 ORZ03746.1 - 0.039 13.4 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) STE PF02200.16 ORZ03746.1 - 0.049 14.1 0.8 8.5 6.8 0.0 3.7 2 1 2 4 4 4 0 STE like transcription factor Frtz PF11768.8 ORZ03746.1 - 0.068 11.5 0.1 0.15 10.4 0.0 1.7 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 ORZ03746.1 - 0.23 10.2 1.5 7.3 5.2 0.0 3.2 3 1 1 4 4 4 0 Nup133 N terminal like MDH PF02315.16 ORZ03747.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Glyco_transf_15 PF01793.16 ORZ03749.1 - 1.5e-108 362.9 10.7 1.9e-108 362.6 10.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 ORZ03750.1 - 2.1e-85 286.8 3.0 2.9e-85 286.4 3.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 ORZ03751.1 - 1.1e-93 314.0 6.1 3.8e-49 167.7 1.1 2.0 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase eIF2A PF08662.11 ORZ03752.1 - 1.1e-85 286.4 1.0 2.4e-81 272.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ORZ03752.1 - 0.0011 19.7 0.1 29 5.8 0.0 5.0 4 1 0 4 4 4 1 WD domain, G-beta repeat F-box-like PF12937.7 ORZ03753.1 - 2.6e-05 24.0 1.7 7e-05 22.6 1.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ03753.1 - 2.8e-05 23.9 2.8 8e-05 22.4 2.8 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 ORZ03754.1 - 6.4e-41 137.6 25.6 9.4e-06 26.3 0.0 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03754.1 - 5e-15 55.6 2.4 0.0059 16.9 0.0 6.7 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 ORZ03754.1 - 6.9e-09 35.5 0.3 1.5e-08 34.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 ORZ03754.1 - 3.5e-07 29.9 0.0 0.073 12.4 0.0 3.9 2 1 0 4 4 4 3 WD40-like domain Nup160 PF11715.8 ORZ03754.1 - 5.2e-06 25.4 11.0 0.52 8.9 0.1 6.2 5 1 2 7 7 7 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 ORZ03754.1 - 2.7e-05 24.2 0.3 0.23 11.5 0.0 4.5 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 ORZ03754.1 - 0.00019 21.0 0.1 0.87 9.0 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) F-box PF00646.33 ORZ03754.1 - 0.00034 20.4 0.3 0.00076 19.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain CDC4_D PF16856.5 ORZ03754.1 - 0.017 15.0 0.5 0.028 14.3 0.5 1.4 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain PQQ_3 PF13570.6 ORZ03754.1 - 0.023 15.2 4.0 16 6.1 0.0 5.2 6 0 0 6 6 6 0 PQQ-like domain Sulfate_transp PF00916.20 ORZ03755.1 - 1e-86 291.1 14.8 1e-86 291.1 14.8 1.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORZ03755.1 - 4.4e-22 77.9 0.0 7.2e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORZ03755.1 - 0.0029 17.9 1.5 0.0048 17.2 0.0 2.2 2 1 0 2 2 2 1 STAS domain SNF2_N PF00176.23 ORZ03756.1 - 7.5e-62 209.1 0.0 1.4e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORZ03756.1 - 3.3e-20 72.5 0.0 6.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORZ03756.1 - 7.4e-09 35.3 4.9 1.4e-08 34.4 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORZ03756.1 - 2.2e-08 33.8 6.4 4.3e-08 32.9 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORZ03756.1 - 4.1e-08 33.4 5.6 9.9e-08 32.2 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORZ03756.1 - 4.3e-08 32.9 7.9 9.9e-08 31.7 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 ORZ03756.1 - 2e-07 31.2 0.0 9.4e-07 29.0 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 ORZ03756.1 - 3.2e-07 30.2 4.6 7.4e-07 29.0 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORZ03756.1 - 2.1e-06 27.6 2.9 6e-06 26.2 2.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORZ03756.1 - 3.8e-06 26.7 4.4 3.5e-05 23.6 4.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DEAD PF00270.29 ORZ03756.1 - 1.4e-05 25.0 0.3 4.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.6 ORZ03756.1 - 0.00011 22.2 6.6 0.00024 21.2 6.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORZ03756.1 - 0.00094 18.9 6.2 0.0023 17.7 6.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 ORZ03756.1 - 0.0016 17.9 0.9 0.0026 17.2 0.9 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-ANAPC11 PF12861.7 ORZ03756.1 - 0.0038 17.3 3.1 0.0084 16.1 3.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORZ03756.1 - 0.0058 16.9 2.9 0.014 15.6 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORZ03756.1 - 0.0062 16.4 3.1 0.018 14.9 3.1 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_14 PF17978.1 ORZ03756.1 - 0.048 14.1 0.9 0.11 12.9 0.5 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DUF840 PF05801.11 ORZ03756.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) TRAF6_Z2 PF18048.1 ORZ03756.1 - 0.19 11.8 2.3 1.9 8.6 0.1 2.9 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 LSM_int_assoc PF16605.5 ORZ03757.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 LSM-interacting associated unstructured CAC1F_C PF16885.5 ORZ03757.1 - 0.21 11.2 7.6 0.25 11.0 7.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term FNIP_N PF14636.6 ORZ03757.1 - 1.9 9.5 8.0 17 6.3 8.0 2.1 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus Phasin PF05597.11 ORZ03757.1 - 2.1 8.4 7.5 0.43 10.6 1.5 2.4 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PKK PF12474.8 ORZ03757.1 - 4.6 7.4 18.9 0.85 9.7 13.6 2.2 1 1 1 2 2 2 0 Polo kinase kinase Sugar_tr PF00083.24 ORZ03758.1 - 6.7e-110 368.0 20.2 9.5e-110 367.5 20.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORZ03758.1 - 1.5e-22 80.0 26.1 9.2e-20 70.8 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORZ03758.1 - 3.3e-06 25.8 0.5 5.9e-06 25.0 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORZ03758.1 - 0.011 14.2 6.5 0.048 12.1 1.4 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2530 PF10745.9 ORZ03758.1 - 0.2 11.9 4.0 0.17 12.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) WD40 PF00400.32 ORZ03759.1 - 5.6e-48 159.9 19.9 1.8e-08 34.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03759.1 - 1.1e-11 44.9 0.2 0.0042 17.4 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORZ03759.1 - 2.4e-06 26.7 0.1 0.48 9.3 0.0 4.3 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORZ03759.1 - 1.1e-05 24.2 0.0 0.053 12.1 0.0 2.9 2 2 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 ORZ03759.1 - 1.2e-05 24.2 5.0 0.1 11.2 0.1 5.2 4 2 2 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 ORZ03759.1 - 0.00028 20.8 0.1 0.016 15.1 0.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 ORZ03759.1 - 0.0019 17.4 0.0 0.16 11.0 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) PD40 PF07676.12 ORZ03759.1 - 0.0047 16.8 3.3 7.5 6.6 0.1 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Methyltransf_13 PF08421.11 ORZ03759.1 - 0.11 12.7 0.0 23 5.3 0.0 2.5 2 1 0 2 2 2 0 Putative zinc binding domain Lactamase_B PF00753.27 ORZ03759.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Linker_histone PF00538.19 ORZ03760.1 - 2e-27 95.4 0.3 2e-27 95.4 0.3 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF126 PF01989.16 ORZ03760.1 - 0.09 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Aconitase X swivel domain DUF572 PF04502.13 ORZ03760.1 - 2.2 7.8 15.3 2.5 7.6 15.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MFS_1 PF07690.16 ORZ03761.1 - 3.4e-35 121.6 23.9 3.4e-35 121.6 23.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORZ03761.1 - 0.0041 16.5 4.0 0.0041 16.5 4.0 2.8 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DNA_pol_lambd_f PF10391.9 ORZ03762.1 - 2.5e-16 59.2 0.1 2.2e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ORZ03762.1 - 1.4e-09 38.2 0.0 6.1e-09 36.1 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 ORZ03762.1 - 5.1e-05 23.8 0.0 0.14 12.8 0.0 2.4 2 1 1 3 3 3 3 Helix-hairpin-helix domain HHH PF00633.23 ORZ03762.1 - 0.024 14.5 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Antimicrobial22 PF16047.5 ORZ03762.1 - 0.035 14.0 0.7 9.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide Cdd1 PF11731.8 ORZ03762.1 - 0.16 12.2 0.0 4.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Pathogenicity locus Kinetochor_Ybp2 PF08568.10 ORZ03763.1 - 5.7e-18 64.7 0.5 7e-18 64.5 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SKA2 PF16740.5 ORZ03763.1 - 0.067 13.0 0.5 0.14 11.9 0.5 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 T4_Gp59_C PF08994.10 ORZ03763.1 - 0.11 13.1 0.4 0.3 11.7 0.1 1.9 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase C-term ANAPC4 PF12896.7 ORZ03764.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 HET PF06985.11 ORZ03764.1 - 0.098 13.0 0.6 0.19 12.1 0.6 1.5 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) HAD PF12710.7 ORZ03765.1 - 7.8e-22 78.6 0.1 9.5e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORZ03765.1 - 0.0016 18.8 0.2 0.0044 17.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_S13 PF00416.22 ORZ03766.1 - 5.1e-55 185.3 2.1 5.8e-55 185.1 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORZ03766.1 - 0.0043 15.9 0.0 0.0058 15.4 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 ORZ03766.1 - 0.25 11.8 1.3 0.42 11.1 0.5 1.8 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DHO_dh PF01180.21 ORZ03767.1 - 1.3e-63 215.0 0.0 1.5e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 ORZ03767.1 - 0.14 11.2 0.7 0.21 10.6 0.7 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase TFIIA PF03153.13 ORZ03768.1 - 2.9 7.8 16.7 3.9 7.4 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APH PF01636.23 ORZ03769.1 - 4.4e-44 151.2 0.0 6.1e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORZ03769.1 - 4.2e-05 23.0 0.0 9.1e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 ORZ03769.1 - 0.00043 19.6 0.0 0.014 14.6 0.0 2.4 1 1 1 2 2 2 1 Fructosamine kinase RIO1 PF01163.22 ORZ03769.1 - 0.0028 17.3 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 ORZ03769.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C2H2 PF00096.26 ORZ03771.1 - 1.1e-21 76.0 23.6 3.8e-06 27.0 1.6 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ03771.1 - 8.7e-15 54.4 22.3 4.4e-05 23.7 0.7 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ03771.1 - 9e-10 38.6 21.7 0.013 16.3 1.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORZ03771.1 - 0.00011 22.8 10.4 0.041 14.5 0.7 3.6 2 2 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORZ03771.1 - 0.0015 18.7 4.0 0.56 10.3 0.9 3.1 2 2 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORZ03771.1 - 0.023 15.0 1.7 0.023 15.0 1.7 3.1 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORZ03771.1 - 0.032 14.0 7.5 0.042 13.6 1.3 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 ORZ03771.1 - 0.11 12.8 5.1 4.8 7.6 0.1 3.3 3 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RPAP2_Rtr1 PF04181.13 ORZ03771.1 - 0.15 12.4 0.2 0.15 12.4 0.2 2.0 2 0 0 2 2 2 0 Rtr1/RPAP2 family zf-TRAF PF02176.18 ORZ03771.1 - 1.4 9.6 7.6 0.67 10.7 1.1 3.0 2 1 1 3 3 3 0 TRAF-type zinc finger PHD PF00628.29 ORZ03773.1 - 2e-11 43.6 5.7 5.2e-11 42.3 5.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 ORZ03773.1 - 1.4e-05 25.1 2.1 1.4e-05 25.1 2.1 2.3 1 1 1 2 2 2 2 CpG binding protein zinc finger C terminal domain PHD_2 PF13831.6 ORZ03773.1 - 0.007 15.9 0.8 0.02 14.5 0.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 ORZ03773.1 - 2.9 8.3 8.6 0.33 11.3 2.0 2.4 2 0 0 2 2 2 0 Ring finger domain Peptidase_S8 PF00082.22 ORZ03774.1 - 5.7e-40 137.4 0.3 8.8e-40 136.8 0.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORZ03774.1 - 1.5e-27 95.5 0.1 3.2e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Corona_NS4 PF03905.13 ORZ03774.1 - 0.013 15.5 0.0 0.065 13.3 0.0 2.1 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 S8_pro-domain PF16470.5 ORZ03774.1 - 0.046 14.5 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain DUF4366 PF14283.6 ORZ03774.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.11 ORZ03774.1 - 0.21 11.0 0.1 0.43 9.9 0.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SCP2 PF02036.17 ORZ03775.1 - 1.9e-08 34.7 0.0 2.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family PUA_2 PF14306.6 ORZ03775.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 PUA-like domain SCP2_2 PF13530.6 ORZ03775.1 - 0.054 13.9 0.0 0.074 13.4 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain PRP21_like_P PF12230.8 ORZ03776.1 - 5.2e-55 186.7 13.4 5.2e-55 186.7 13.4 3.1 2 1 1 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 ORZ03776.1 - 1.1e-37 127.7 4.4 1.6e-18 66.4 1.0 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 ORZ03776.1 - 1.4e-06 28.0 0.1 3.7e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 ORZ03776.1 - 3.2e-05 23.4 0.2 7.3e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger YukD PF08817.10 ORZ03776.1 - 0.041 14.6 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 ORZ03776.1 - 0.053 14.0 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain FAR1 PF03101.15 ORZ03777.1 - 1.2e-05 25.9 0.8 1.2e-05 25.9 0.8 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain Shadoo PF14999.6 ORZ03777.1 - 1.7 8.7 8.8 0.21 11.7 3.8 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2205 PF10224.9 ORZ03778.1 - 9.1e-17 60.8 0.3 1.1e-16 60.5 0.3 1.1 1 0 0 1 1 1 1 Short coiled-coil protein JIP_LZII PF16471.5 ORZ03778.1 - 0.0017 18.5 1.0 0.0036 17.4 1.0 1.5 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II CENP-H PF05837.12 ORZ03778.1 - 0.0023 18.3 1.9 0.0027 18.1 1.9 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) YabA PF06156.13 ORZ03778.1 - 0.003 18.2 0.1 0.0031 18.1 0.1 1.1 1 0 0 1 1 1 1 Initiation control protein YabA SKA2 PF16740.5 ORZ03778.1 - 0.0039 17.0 0.9 0.005 16.6 0.9 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Sas10_Utp3 PF04000.15 ORZ03778.1 - 0.033 14.8 0.1 0.038 14.6 0.1 1.1 1 0 0 1 1 1 0 Sas10/Utp3/C1D family HALZ PF02183.18 ORZ03778.1 - 0.086 13.1 2.4 0.91 9.8 0.9 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper EMP24_GP25L PF01105.24 ORZ03778.1 - 0.11 12.5 0.2 0.12 12.3 0.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD WD40 PF00400.32 ORZ03779.1 - 6.7e-48 159.7 37.1 1.6e-08 35.0 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03779.1 - 6.9e-16 58.3 12.8 0.04 14.2 0.0 6.9 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ03779.1 - 5.3e-06 26.4 3.0 0.0012 18.8 0.2 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Big_2 PF02368.18 ORZ03779.1 - 0.0072 16.2 1.3 0.4 10.6 0.1 3.2 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 2) Coatomer_WDAD PF04053.14 ORZ03779.1 - 0.019 14.0 3.2 0.026 13.6 1.1 2.1 2 1 1 3 3 3 0 Coatomer WD associated region Nucleoporin_N PF08801.11 ORZ03779.1 - 0.021 13.6 0.7 6.7 5.3 0.0 3.4 3 1 0 4 4 4 0 Nup133 N terminal like Kelch_2 PF07646.15 ORZ03779.1 - 2.7 8.1 5.8 11 6.2 0.1 3.8 3 0 0 3 3 3 0 Kelch motif IKI3 PF04762.12 ORZ03779.1 - 5.7 4.8 11.3 2.5 6.0 0.8 2.7 3 1 1 4 4 4 0 IKI3 family DUF727 PF05303.12 ORZ03780.1 - 5.1e-09 36.1 0.8 7.9e-09 35.5 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF727) RAB3GAP2_N PF14655.6 ORZ03780.1 - 0.0026 17.1 1.7 0.0034 16.7 1.7 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4834 PF16118.5 ORZ03780.1 - 0.14 13.1 0.9 0.27 12.2 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 ORZ03780.1 - 0.2 11.6 11.4 0.23 11.4 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 ORZ03780.1 - 0.4 9.7 7.4 0.54 9.3 7.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Aa_trans PF01490.18 ORZ03781.1 - 5.8e-55 186.6 26.4 7.3e-55 186.3 26.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAM104 PF15434.6 ORZ03781.1 - 0.0041 17.7 2.5 0.0088 16.6 1.2 2.0 1 1 1 2 2 2 1 Family 104 Metallophos PF00149.28 ORZ03783.1 - 5.5e-40 138.1 0.2 6.9e-40 137.7 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORZ03783.1 - 2.8e-16 59.7 0.4 3.1e-15 56.3 0.1 2.6 2 1 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain ECH_1 PF00378.20 ORZ03784.1 - 7.4e-50 169.6 0.0 8.7e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORZ03784.1 - 1.2e-30 107.1 0.0 1.4e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RGS PF00615.19 ORZ03785.1 - 3.7e-06 27.2 0.2 4.8e-05 23.6 0.2 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Malate_synthase PF01274.22 ORZ03786.1 - 1.1e-227 756.4 0.0 1.4e-227 756.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Pyrophosphatase PF00719.19 ORZ03787.1 - 1.8e-49 167.6 0.1 3.5e-49 166.7 0.1 1.5 2 0 0 2 2 2 1 Inorganic pyrophosphatase ADH_N PF08240.12 ORZ03788.1 - 6.7e-31 106.4 0.7 1.2e-30 105.6 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORZ03788.1 - 3.1e-28 98.3 0.0 5.9e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORZ03788.1 - 3.7e-12 46.2 0.6 2.7e-11 43.4 0.6 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORZ03788.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORZ03788.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltr_RsmB-F PF01189.17 ORZ03789.1 - 3.9e-37 127.9 0.0 2.5e-36 125.2 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORZ03789.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF1127 PF06568.11 ORZ03791.1 - 2.3 8.0 5.8 5.2 6.9 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1127) DUF1906 PF08924.11 ORZ03792.1 - 0.012 15.8 1.1 0.02 15.0 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Glyco_hydro_8 PF01270.17 ORZ03793.1 - 6.4e-22 77.8 3.3 2.4e-21 76.0 3.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 Ribosomal_L29e PF01779.17 ORZ03794.1 - 0.0011 19.2 14.3 0.053 13.8 10.8 2.3 2 0 0 2 2 2 2 Ribosomal L29e protein family SAM_2 PF07647.17 ORZ03795.1 - 4.6e-06 26.6 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORZ03795.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SUIM_assoc PF16619.5 ORZ03795.1 - 0.04 14.0 5.7 0.13 12.4 5.7 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Tmemb_18A PF09771.9 ORZ03795.1 - 0.066 13.6 0.5 0.11 12.9 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 188 IGR PF09597.10 ORZ03795.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 IGR protein motif CAF1 PF04857.20 ORZ03796.1 - 1.5e-71 241.2 0.4 2.1e-71 240.7 0.4 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Peptidase_S15 PF02129.18 ORZ03796.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Transket_pyr PF02779.24 ORZ03797.1 - 6e-62 208.5 0.0 9.1e-62 207.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORZ03797.1 - 8.8e-49 165.1 0.0 1.6e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORZ03797.1 - 4e-47 160.6 0.0 7e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component GDP_Man_Dehyd PF16363.5 ORZ03797.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YhzD PF14120.6 ORZ03797.1 - 0.16 12.1 0.7 0.41 10.8 0.7 1.6 1 0 0 1 1 1 0 YhzD-like protein Cpn60_TCP1 PF00118.24 ORZ03798.1 - 1.4e-159 531.9 10.8 1.6e-159 531.7 10.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 ORZ03798.1 - 0.0088 15.6 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 EAL domain Nitro_FeMo-Co PF02579.17 ORZ03798.1 - 0.017 15.5 0.1 0.095 13.0 0.1 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor DrsE PF02635.15 ORZ03798.1 - 0.021 15.2 0.1 0.13 12.7 0.0 2.3 3 0 0 3 3 3 0 DsrE/DsrF-like family Nop52 PF05997.12 ORZ03799.1 - 3.5e-66 223.1 0.5 3.5e-66 223.1 0.5 1.2 1 1 0 1 1 1 1 Nucleolar protein,Nop52 CHASE6_C PF17150.4 ORZ03799.1 - 0.062 14.0 0.7 0.58 10.9 0.0 2.7 3 1 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain tRNA_synthFbeta PF17759.1 ORZ03800.1 - 2.9e-48 164.2 0.0 2.5e-47 161.1 0.0 2.2 2 1 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 ORZ03800.1 - 5.8e-31 106.6 0.2 9.9e-30 102.6 0.1 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 ORZ03800.1 - 4.1e-27 95.0 0.1 6.8e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 ORZ03800.1 - 2.8e-19 69.2 0.0 9.2e-17 61.1 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 ORZ03800.1 - 0.0018 17.8 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Herpes_V23 PF01802.17 ORZ03800.1 - 0.069 12.6 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus VP23 like capsid protein DUF2740 PF10872.8 ORZ03800.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) MMM1 PF10296.9 ORZ03801.1 - 4.9e-06 25.8 0.6 2.2e-05 23.7 0.0 2.3 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 ORZ03801.1 - 0.0061 17.0 0.0 0.025 15.0 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain ADH_zinc_N PF00107.26 ORZ03802.1 - 4e-22 78.6 2.3 5e-22 78.3 1.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORZ03802.1 - 8e-11 43.1 0.2 1.6e-10 42.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORZ03802.1 - 2.3e-07 30.7 0.1 7.2e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Brix PF04427.18 ORZ03803.1 - 1.6e-27 96.8 0.4 1.6e-27 96.8 0.4 1.5 2 0 0 2 2 2 1 Brix domain HAD_SAK_2 PF18143.1 ORZ03803.1 - 0.05 13.9 0.1 0.094 13.0 0.1 1.6 1 1 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Gag_p15 PF08723.10 ORZ03803.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Gag protein p15 Peptidase_S64 PF08192.11 ORZ03803.1 - 0.92 7.9 4.8 1.1 7.7 4.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 PIG-L PF02585.17 ORZ03803.1 - 1.2 9.8 3.4 3.6 8.2 1.2 2.2 1 1 1 2 2 2 0 GlcNAc-PI de-N-acetylase Prenyltrans PF00432.21 ORZ03804.1 - 1.1e-66 220.2 5.3 3.3e-15 55.5 0.1 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ORZ03804.1 - 2.2e-08 33.6 0.0 4.2e-05 22.8 0.0 3.1 1 1 2 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORZ03804.1 - 1.1e-06 28.0 0.0 0.016 14.3 0.0 3.5 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 ORZ03804.1 - 0.00016 20.8 0.0 0.082 11.9 0.0 3.3 1 1 2 3 3 3 2 A-macroglobulin TED domain RRM_3 PF08777.11 ORZ03805.1 - 7.9e-12 45.1 0.3 1.6e-07 31.3 0.1 3.9 3 2 0 3 3 3 2 RNA binding motif RRM_1 PF00076.22 ORZ03805.1 - 1.5e-10 40.7 0.0 3.9e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 ORZ03805.1 - 1.3e-08 34.7 0.0 5.5e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 La domain JHD PF17811.1 ORZ03806.1 - 3.2e-12 46.9 0.0 6.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 ORZ03806.1 - 1.1e-09 38.7 0.2 3e-08 34.1 0.2 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 ORZ03806.1 - 7.2e-08 32.5 3.1 8.1e-08 32.3 0.2 2.3 2 1 0 2 2 2 1 Cupin-like domain PHD PF00628.29 ORZ03806.1 - 0.001 18.9 15.0 0.0019 18.1 15.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORZ03806.1 - 6.1 6.5 11.1 15 5.3 11.1 1.7 1 0 0 1 1 1 0 PHD-finger YtxH PF12732.7 ORZ03807.1 - 0.0042 17.6 23.6 0.09 13.3 7.9 3.3 1 1 2 3 3 3 3 YtxH-like protein DUF948 PF06103.11 ORZ03807.1 - 0.046 14.0 5.8 3 8.2 1.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2981 PF11200.8 ORZ03807.1 - 0.6 9.8 6.8 0.69 9.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Apolipoprotein PF01442.18 ORZ03807.1 - 0.79 9.6 16.7 2 8.3 16.7 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 ORZ03807.1 - 2.7 8.7 22.7 0.79 10.4 9.8 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.6 ORZ03807.1 - 3.1 8.2 33.7 4.2 7.8 6.3 4.0 1 1 2 3 3 3 0 MT0933-like antitoxin protein Rcd1 PF04078.13 ORZ03808.1 - 3.4e-126 419.8 3.8 4e-126 419.6 3.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PDCD2_C PF04194.13 ORZ03809.1 - 1.8 8.6 3.8 0.48 10.5 0.9 1.7 2 1 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain ACOX PF01756.19 ORZ03810.1 - 2e-40 138.3 0.0 4.2e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORZ03810.1 - 1.8e-20 73.7 0.0 3.7e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORZ03810.1 - 3.8e-11 43.0 0.0 7.9e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORZ03810.1 - 0.0077 16.9 0.0 0.024 15.3 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORZ03810.1 - 0.015 15.5 0.2 0.053 13.7 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Ras PF00071.22 ORZ03811.1 - 6e-50 169.0 0.0 6.9e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORZ03811.1 - 8.3e-19 68.0 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORZ03811.1 - 9.6e-06 25.2 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PglD_N PF17836.1 ORZ03811.1 - 0.15 12.7 0.0 0.39 11.4 0.0 1.7 1 1 0 1 1 1 0 PglD N-terminal domain CN_hydrolase PF00795.22 ORZ03812.1 - 2.9e-57 194.0 0.0 3.4e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Gpr1_Fun34_YaaH PF01184.19 ORZ03813.1 - 0.0024 17.5 3.8 0.19 11.3 0.0 2.4 2 1 0 2 2 2 2 GPR1/FUN34/yaaH family UPF0542 PF15086.6 ORZ03813.1 - 0.25 11.3 1.1 1.6 8.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 DUF1515 PF07439.11 ORZ03814.1 - 0.44 10.6 2.3 0.52 10.4 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Atg14 PF10186.9 ORZ03814.1 - 0.61 9.1 4.7 0.75 8.8 4.7 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 ORZ03814.1 - 0.87 9.7 10.8 9.9 6.3 10.3 2.5 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Mpv17_PMP22 PF04117.12 ORZ03815.1 - 4.3e-17 62.1 0.8 1.1e-16 60.8 0.1 1.9 1 1 1 2 2 2 1 Mpv17 / PMP22 family Gpr1_Fun34_YaaH PF01184.19 ORZ03816.1 - 4.3e-34 117.9 12.9 5.6e-34 117.6 12.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.7 ORZ03816.1 - 7.1 6.9 10.4 0.69 10.2 3.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3784) WD40 PF00400.32 ORZ03817.1 - 1.6e-68 224.9 30.7 1.4e-12 47.9 0.4 9.2 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03817.1 - 3.4e-25 88.1 8.4 4e-06 27.0 0.1 5.9 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 ORZ03817.1 - 4.8e-13 49.4 0.1 3.5e-12 46.7 0.1 2.2 2 0 0 2 2 2 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 ORZ03817.1 - 3.1e-12 46.1 0.1 0.002 17.2 0.0 4.9 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORZ03817.1 - 7.5e-10 39.0 0.7 0.0093 15.9 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 ORZ03817.1 - 7.1e-07 28.8 3.5 0.17 11.2 0.0 5.0 3 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 ORZ03817.1 - 4.2e-06 25.7 7.8 1 7.9 0.1 5.8 3 3 3 6 6 6 2 Nucleoporin Nup120/160 Frtz PF11768.8 ORZ03817.1 - 6.1e-06 24.8 0.0 0.0038 15.6 0.0 2.8 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 ORZ03817.1 - 0.0006 18.7 2.5 0.32 9.7 0.0 3.3 2 1 0 3 3 3 2 Nup133 N terminal like IKI3 PF04762.12 ORZ03817.1 - 0.0019 16.3 0.6 0.72 7.8 0.0 2.5 3 0 0 3 3 3 2 IKI3 family WD40_like PF17005.5 ORZ03817.1 - 0.0055 16.1 0.0 18 4.6 0.0 4.4 4 1 1 5 5 5 0 WD40-like domain Proteasome_A_N PF10584.9 ORZ03817.1 - 0.011 15.4 1.6 3.8 7.3 0.0 4.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 ORZ03817.1 - 0.054 12.0 0.1 1.7 7.1 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain FAD_binding_9 PF08021.11 ORZ03817.1 - 0.12 12.6 0.0 6.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain PD40 PF07676.12 ORZ03817.1 - 0.3 11.1 14.3 2.7 8.1 0.1 4.5 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat Methyltransf_25 PF13649.6 ORZ03818.1 - 8.1e-15 55.3 0.0 1.9e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORZ03818.1 - 1.9e-12 47.4 0.0 4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORZ03818.1 - 1.5e-11 44.8 0.0 3.4e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORZ03818.1 - 3.7e-09 36.5 0.0 1.2e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORZ03818.1 - 2.7e-07 30.2 0.0 0.00021 20.8 0.0 3.1 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_12 PF08242.12 ORZ03818.1 - 0.00058 20.6 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORZ03818.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 ORZ03818.1 - 0.019 15.1 0.0 0.055 13.6 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 ORZ03818.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TFIIA PF03153.13 ORZ03818.1 - 0.77 9.7 8.7 1.3 8.9 8.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PsbJ PF01788.17 ORZ03820.1 - 0.16 11.9 0.3 0.3 11.0 0.3 1.5 1 0 0 1 1 1 0 PsbJ SPA PF08616.10 ORZ03821.1 - 1.6e-37 128.0 0.0 2.7e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 ORZ03821.1 - 2.8e-23 82.9 0.1 2.9e-19 69.9 0.0 2.5 1 1 1 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 ORZ03821.1 - 2.9e-09 36.1 0.0 0.00034 19.4 0.0 3.6 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 ORZ03821.1 - 8.5e-07 28.8 0.0 0.0017 18.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) YidD PF01809.18 ORZ03822.1 - 0.0028 17.5 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Putative membrane protein insertion efficiency factor MFS_1 PF07690.16 ORZ03823.1 - 5.5e-31 107.8 28.6 2e-30 105.9 28.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ03823.1 - 3.4e-10 39.4 12.1 3.4e-10 39.4 12.1 3.5 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ORZ03823.1 - 0.00022 19.8 5.7 0.00022 19.8 5.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Adaptin_N PF01602.20 ORZ03824.1 - 1.1e-143 479.6 5.1 1.4e-143 479.2 5.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORZ03824.1 - 1.7e-20 73.6 3.5 2.8e-18 66.5 0.0 3.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORZ03824.1 - 2.3e-09 37.5 3.9 0.0062 16.9 0.3 5.0 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.22 ORZ03824.1 - 2.1e-06 27.5 4.6 0.27 11.6 0.0 7.7 9 0 0 9 9 9 1 HEAT repeat Cohesin_HEAT PF12765.7 ORZ03824.1 - 0.0019 18.4 0.0 0.0068 16.7 0.0 1.9 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Svf1_C PF17187.4 ORZ03824.1 - 0.14 12.0 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Svf1-like C-terminal lipocalin-like domain GRIP PF01465.20 ORZ03824.1 - 0.16 11.9 0.5 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 GRIP domain HEAT_EZ PF13513.6 ORZ03824.1 - 0.44 11.1 2.0 33 5.1 0.0 4.7 5 1 1 7 7 7 0 HEAT-like repeat ThiF PF00899.21 ORZ03825.1 - 2.5e-34 118.7 0.0 4.3e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORZ03825.1 - 2.6e-05 24.5 0.0 9e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 ORZ03825.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 ORZ03825.1 - 0.018 15.5 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 ORZ03825.1 - 0.04 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 ORZ03825.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PX PF00787.24 ORZ03826.1 - 8.7e-23 80.5 0.2 3.2e-22 78.7 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORZ03826.1 - 7.1e-07 29.0 10.3 0.0022 17.6 0.3 2.4 2 0 0 2 2 2 2 Vps5 C terminal like GCP_N_terminal PF17681.1 ORZ03826.1 - 0.00013 21.7 0.9 0.00023 20.9 0.9 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Peptidase_C10 PF01640.17 ORZ03826.1 - 0.0014 18.9 1.9 0.0018 18.6 0.3 1.9 1 1 0 1 1 1 1 Peptidase C10 family BAR_3_WASP_bdg PF10456.9 ORZ03826.1 - 0.017 14.6 3.7 0.19 11.2 0.1 2.3 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein GLTP PF08718.11 ORZ03826.1 - 0.13 12.6 2.0 16 5.8 0.5 2.5 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) Fasciclin PF02469.22 ORZ03829.1 - 1.5e-25 89.9 2.1 4.1e-14 52.9 0.3 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF416 PF04222.12 ORZ03829.1 - 0.025 14.0 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF416) ssDBP_DBD PF18361.1 ORZ03829.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain TFIIA PF03153.13 ORZ03830.1 - 9.4 6.1 26.7 13 5.7 26.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COX5B PF01215.19 ORZ03832.1 - 7.6e-45 151.8 0.0 9.3e-45 151.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 ORZ03832.1 - 0.0025 17.5 0.2 0.43 10.4 0.0 2.2 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zf-CHCC PF10276.9 ORZ03832.1 - 0.008 16.2 0.7 0.014 15.5 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger domain Lactamase_B PF00753.27 ORZ03833.1 - 6.9e-11 42.5 2.1 0.00028 20.9 0.8 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORZ03833.1 - 7.6e-05 22.3 0.3 0.00014 21.4 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rhodanese PF00581.20 ORZ03833.1 - 0.0011 19.5 0.1 0.0032 18.0 0.1 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Acetyltransf_17 PF17668.1 ORZ03833.1 - 0.044 14.6 0.1 2.5 8.9 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain p450 PF00067.22 ORZ03834.1 - 2.4e-73 247.5 0.0 8.4e-73 245.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 RasGEF PF00617.19 ORZ03834.1 - 5.5e-50 170.0 0.1 1.1e-49 169.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORZ03834.1 - 1.9e-15 57.0 3.9 6.5e-15 55.3 3.9 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif WD40 PF00400.32 ORZ03835.1 - 2.1e-27 94.8 3.8 4.1e-07 30.6 0.4 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03835.1 - 1.1e-17 64.1 0.0 0.00067 19.9 0.0 5.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 ORZ03835.1 - 7.8e-11 41.4 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 ORZ03835.1 - 9.4e-06 24.8 1.0 0.24 10.3 0.1 3.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORZ03835.1 - 2.4e-05 23.2 0.8 0.00029 19.7 0.2 2.5 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORZ03835.1 - 0.0011 17.9 0.4 2 7.0 0.1 3.6 2 1 2 4 4 4 1 Nup133 N terminal like DUF1513 PF07433.11 ORZ03835.1 - 0.0014 17.8 1.1 1.6 7.7 0.0 3.4 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) PALB2_WD40 PF16756.5 ORZ03835.1 - 0.0014 17.6 0.5 0.04 12.9 0.1 2.7 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 ORZ03835.1 - 0.0071 15.9 0.1 0.67 9.5 0.0 2.9 1 1 1 2 2 2 1 PQQ-like domain ELYS-bb PF16687.5 ORZ03835.1 - 0.027 13.1 0.0 1.1 7.8 0.0 2.1 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin WD40_like PF17005.5 ORZ03835.1 - 0.03 13.6 0.1 37 3.5 0.0 2.3 1 1 0 1 1 1 0 WD40-like domain BBS2_Mid PF14783.6 ORZ03835.1 - 0.08 13.0 0.0 6.5 6.8 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region GCOM2 PF15328.6 ORZ03835.1 - 0.16 12.4 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 F-box PF00646.33 ORZ03836.1 - 4.1e-06 26.5 0.1 8.9e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORZ03836.1 - 0.00026 20.8 0.1 0.00049 19.9 0.1 1.4 1 0 0 1 1 1 1 F-box-like DUF454 PF04304.13 ORZ03837.1 - 0.12 12.3 2.5 0.22 11.6 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF454) COPI_C PF06957.11 ORZ03838.1 - 9.8e-147 488.9 0.3 1.3e-146 488.6 0.3 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 ORZ03838.1 - 1.2e-143 479.4 0.0 3e-143 478.1 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 ORZ03838.1 - 1.5e-42 142.7 13.8 1.4e-08 35.3 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03838.1 - 5.6e-10 39.4 0.3 0.0046 17.2 0.0 6.2 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 ORZ03838.1 - 0.088 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS Nup160 PF11715.8 ORZ03838.1 - 0.2 10.2 7.8 1.7 7.2 0.2 4.0 1 1 3 4 4 4 0 Nucleoporin Nup120/160 HSP70 PF00012.20 ORZ03839.1 - 7.9e-261 866.5 6.7 9e-261 866.3 6.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORZ03839.1 - 8.4e-15 54.4 0.1 6.7e-14 51.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein SAPIS-gp6 PF16722.5 ORZ03839.1 - 0.0022 18.3 2.1 0.0067 16.8 2.1 1.8 1 0 0 1 1 1 1 Pathogenicity island protein gp6 in Staphylococcus Hydantoinase_A PF01968.18 ORZ03839.1 - 0.0058 15.9 0.1 0.014 14.7 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORZ03839.1 - 0.015 14.8 0.0 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 ORZ03839.1 - 0.015 15.0 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 ORZ03839.1 - 0.016 14.5 0.4 0.32 10.2 0.0 2.2 2 0 0 2 2 2 0 StbA protein MutS_III PF05192.18 ORZ03839.1 - 1.3 9.2 3.7 2.9 8.1 0.7 2.4 2 1 0 2 2 2 0 MutS domain III Pkinase PF00069.25 ORZ03840.1 - 6.1e-59 199.5 0.0 8.4e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03840.1 - 4.8e-28 98.1 0.0 7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 ORZ03840.1 - 3.9e-07 30.1 0.5 1.2e-06 28.4 0.5 1.9 1 0 0 1 1 1 1 PX domain Pkinase_C PF00433.24 ORZ03840.1 - 3.6e-05 24.4 2.9 0.00018 22.2 2.9 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 ORZ03840.1 - 0.0044 16.7 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORZ03840.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORZ03840.1 - 0.048 12.6 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORZ03840.1 - 0.1 11.3 0.0 0.21 10.3 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase ATP_bind_1 PF03029.17 ORZ03841.1 - 4.6e-79 265.6 0.5 6.4e-79 265.1 0.5 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ORZ03841.1 - 3.3e-07 30.0 0.8 8.3e-06 25.5 0.8 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 ORZ03841.1 - 7.6e-05 22.9 0.0 0.00014 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 ORZ03841.1 - 0.0001 21.9 0.1 0.33 10.5 0.0 2.4 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 ORZ03841.1 - 0.00012 21.8 0.0 0.00037 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORZ03841.1 - 0.00015 21.8 0.0 0.0015 18.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORZ03841.1 - 0.00031 20.3 0.0 0.006 16.1 0.0 2.6 2 1 0 3 3 3 1 Ferrous iron transport protein B G-alpha PF00503.20 ORZ03841.1 - 0.00032 20.0 0.2 0.11 11.7 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 ORZ03841.1 - 0.00067 19.9 0.0 0.002 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORZ03841.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.18 ORZ03841.1 - 0.00084 18.8 1.1 0.009 15.4 0.1 2.6 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.6 ORZ03841.1 - 0.0017 18.8 0.0 0.0045 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PP2C_C PF07830.13 ORZ03841.1 - 0.0021 18.5 0.9 0.008 16.6 0.9 2.0 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain MeaB PF03308.16 ORZ03841.1 - 0.0031 16.5 0.1 1.4 7.8 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 ORZ03841.1 - 0.0037 17.6 0.1 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 ORZ03841.1 - 0.0045 16.8 0.0 0.34 10.7 0.0 2.4 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 ORZ03841.1 - 0.0073 16.0 0.1 0.034 13.8 0.0 2.2 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 ORZ03841.1 - 0.0097 15.8 0.0 5.1 7.0 0.0 3.1 3 1 0 3 3 3 0 RsgA GTPase AAA_30 PF13604.6 ORZ03841.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORZ03841.1 - 0.012 15.5 0.2 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORZ03841.1 - 0.014 14.9 0.1 0.036 13.6 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 ORZ03841.1 - 0.014 14.6 0.0 0.014 14.6 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.9 ORZ03841.1 - 0.015 15.0 0.1 0.65 9.7 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 ORZ03841.1 - 0.017 15.1 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORZ03841.1 - 0.018 15.6 0.2 0.26 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 ORZ03841.1 - 0.029 14.3 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 ORZ03841.1 - 0.03 14.5 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 ORZ03841.1 - 0.053 13.4 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 ORZ03841.1 - 0.057 13.1 0.4 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase AAA_23 PF13476.6 ORZ03841.1 - 0.063 13.8 0.0 0.69 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 ORZ03841.1 - 0.07 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 ORZ03841.1 - 0.071 12.6 0.0 2.6 7.5 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORZ03841.1 - 0.088 12.2 0.0 1.1 8.6 0.0 2.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_17 PF13207.6 ORZ03841.1 - 0.088 13.2 0.7 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORZ03841.1 - 0.094 12.8 0.0 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Fumerase PF05681.14 ORZ03841.1 - 0.099 12.1 0.8 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Fumarate hydratase (Fumerase) AAA_14 PF13173.6 ORZ03841.1 - 0.11 12.5 0.1 0.72 9.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 ORZ03841.1 - 0.15 12.5 1.2 6.7 7.1 0.0 2.8 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Mitofilin PF09731.9 ORZ03841.1 - 0.36 9.6 2.4 0.53 9.1 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BCIP PF13862.6 ORZ03842.1 - 1.2e-65 221.2 2.6 1.6e-65 220.8 2.6 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein MRP-S33 PF08293.11 ORZ03842.1 - 0.16 12.2 5.0 0.55 10.5 1.4 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit S27 DUF4770 PF15994.5 ORZ03842.1 - 0.32 11.2 4.1 0.67 10.2 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Carboxyl_trans PF01039.22 ORZ03843.1 - 4.9e-149 497.1 0.0 6.5e-149 496.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ORZ03843.1 - 0.064 12.7 0.2 10 5.5 0.0 2.4 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 ORZ03843.1 - 0.11 11.9 1.8 0.46 9.8 0.1 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Complex1_LYR PF05347.15 ORZ03844.1 - 3.5e-08 33.4 0.3 6.9e-08 32.4 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 ORZ03844.1 - 0.074 13.7 0.9 0.13 12.9 0.9 1.6 1 1 0 1 1 1 0 Complex1_LYR-like rRNA_proc-arch PF13234.6 ORZ03845.1 - 1.1e-75 255.1 0.0 1.8e-75 254.3 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 ORZ03845.1 - 6.8e-56 188.4 1.0 6.8e-56 188.4 1.0 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 ORZ03845.1 - 5e-19 68.7 0.1 1.6e-17 63.8 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ03845.1 - 4.3e-08 33.5 0.1 1.3e-06 28.7 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ03845.1 - 2.2e-05 24.5 0.0 5.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORZ03845.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Cwf_Cwc_15 PF04889.12 ORZ03845.1 - 0.48 10.1 5.8 0.91 9.2 5.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mg_trans_NIPA PF05653.14 ORZ03846.1 - 2.9e-105 351.6 21.1 3.4e-105 351.4 21.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORZ03846.1 - 2.2e-06 27.9 4.0 2.2e-06 27.9 4.0 3.4 3 1 0 3 3 3 2 EamA-like transporter family WD40 PF00400.32 ORZ03847.1 - 1.6e-29 101.5 0.7 1.3e-09 38.5 0.0 6.1 7 0 0 7 7 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03847.1 - 7.2e-11 42.3 0.1 0.00029 21.1 0.1 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ03847.1 - 0.0038 17.1 0.1 0.25 11.2 0.0 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A betaPIX_CC PF16523.5 ORZ03847.1 - 0.0047 16.7 0.5 0.45 10.4 0.0 2.4 2 0 0 2 2 2 1 betaPIX coiled coil bZIP_1 PF00170.21 ORZ03847.1 - 0.0088 16.1 0.5 0.017 15.2 0.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor Nup160 PF11715.8 ORZ03847.1 - 0.032 12.9 0.7 1.8 7.1 0.0 2.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORZ03847.1 - 0.1 11.6 0.0 0.93 8.4 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Prominin PF05478.11 ORZ03847.1 - 0.13 10.2 0.4 0.18 9.7 0.4 1.1 1 0 0 1 1 1 0 Prominin Csm1_N PF18504.1 ORZ03847.1 - 0.16 12.3 1.6 0.41 11.0 1.6 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain YabA PF06156.13 ORZ03847.1 - 0.2 12.3 0.2 2.3 8.9 0.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 ORZ03847.1 - 0.69 9.7 2.4 1.3 8.9 2.4 1.4 1 0 0 1 1 1 0 Septum formation initiator MutS_V PF00488.21 ORZ03848.1 - 1.1e-45 156.0 3.8 1.3e-45 155.7 1.5 2.2 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 ORZ03848.1 - 6.8e-05 23.2 0.2 0.00019 21.7 0.1 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 ORZ03848.1 - 0.00012 22.4 0.0 0.00019 21.7 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.6 ORZ03848.1 - 0.031 14.0 0.1 0.084 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORZ03848.1 - 0.099 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 ORZ03848.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Forkhead PF00250.18 ORZ03849.1 - 1e-33 115.4 0.0 3.2e-33 113.9 0.0 1.8 2 0 0 2 2 2 1 Forkhead domain AP3D1 PF06375.11 ORZ03850.1 - 0.0091 16.3 7.6 0.0091 16.3 7.6 2.2 2 1 0 2 2 2 1 AP-3 complex subunit delta-1 YL1 PF05764.13 ORZ03850.1 - 7.2 6.6 27.7 13 5.8 27.7 1.4 1 1 0 1 1 1 0 YL1 nuclear protein MFS_1 PF07690.16 ORZ03851.1 - 6.1e-10 38.6 38.4 1.6e-09 37.2 37.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3669 PF12417.8 ORZ03851.1 - 0.13 12.5 0.1 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 Zinc finger protein FKBP_C PF00254.28 ORZ03852.1 - 3.5e-18 65.7 0.0 4.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BatA PF07584.11 ORZ03852.1 - 0.036 14.4 0.8 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Aconitase PF00330.20 ORZ03853.1 - 4.7e-155 517.1 0.1 5.9e-155 516.8 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORZ03853.1 - 2.8e-38 131.2 0.0 5e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain ArfGap PF01412.18 ORZ03854.1 - 9.8e-38 128.8 0.0 3e-37 127.3 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 ORZ03854.1 - 6.2e-23 81.7 9.7 1.3e-22 80.7 9.7 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORZ03854.1 - 2.1e-14 53.9 0.3 4.4e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 ORZ03854.1 - 0.04 14.3 0.5 0.04 14.3 0.5 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain BAR PF03114.18 ORZ03854.1 - 0.24 11.0 6.7 2.9 7.4 6.5 2.3 1 1 0 1 1 1 0 BAR domain p450 PF00067.22 ORZ03855.1 - 1.4e-97 327.4 0.0 1.9e-97 326.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORZ03855.1 - 1.8e-36 125.8 0.0 3.1e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORZ03855.1 - 2.8e-28 98.9 0.8 5.3e-28 98.0 0.8 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORZ03855.1 - 5.4e-17 62.4 0.0 1.2e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF1687 PF07955.11 ORZ03855.1 - 0.12 12.9 0.2 1.3 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) F-box-like PF12937.7 ORZ03857.1 - 7.5e-07 28.9 0.0 1.9e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ03857.1 - 8.3e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF3156 PF11354.8 ORZ03857.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) efThoc1 PF11957.8 ORZ03858.1 - 2.5e-77 260.6 1.2 9.8e-77 258.7 1.2 1.7 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor ResIII PF04851.15 ORZ03858.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TPR_22 PF18833.1 ORZ03858.1 - 0.073 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat POT1PC PF16686.5 ORZ03859.1 - 9.3e-10 38.6 0.1 1.2e-06 28.5 0.0 3.3 2 1 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 ORZ03859.1 - 0.0033 17.3 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 ORZ03859.1 - 0.099 12.6 0.3 20 5.3 0.0 2.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RecR PF02132.15 ORZ03859.1 - 0.34 10.5 2.2 0.89 9.2 2.2 1.7 1 0 0 1 1 1 0 RecR protein WD40 PF00400.32 ORZ03860.1 - 0.0005 20.8 12.5 3.2 8.8 0.1 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 ORZ03860.1 - 0.00068 19.4 0.8 0.0081 15.8 0.8 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 FH2 PF02181.23 ORZ03861.1 - 3.6e-73 246.8 6.6 3.6e-73 246.8 6.6 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORZ03861.1 - 5.7e-38 130.4 4.0 2.2e-37 128.5 0.5 3.1 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORZ03861.1 - 4.9e-33 114.4 0.0 4.9e-33 114.4 0.0 2.5 3 0 0 3 3 3 1 Diaphanous FH3 Domain ATP-synt_E PF05680.12 ORZ03861.1 - 0.17 12.2 8.5 2.7 8.4 4.7 3.0 2 0 0 2 2 2 0 ATP synthase E chain PRKCSH-like PF12999.7 ORZ03862.1 - 8.1e-52 175.5 3.8 8.1e-52 175.5 3.8 2.6 2 1 0 3 3 3 1 Glucosidase II beta subunit-like HAP1_N PF04849.13 ORZ03862.1 - 0.007 15.6 5.5 0.007 15.6 5.5 2.9 2 2 0 2 2 2 1 HAP1 N-terminal conserved region Ldl_recept_a PF00057.18 ORZ03862.1 - 0.038 14.2 1.6 0.038 14.2 1.6 3.2 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A ATG16 PF08614.11 ORZ03862.1 - 0.4 10.9 17.9 0.38 10.9 7.3 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 ORZ03862.1 - 4.5 6.5 19.3 4.8e+02 -0.1 19.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 ORZ03862.1 - 4.6 7.3 13.6 1.4 9.0 4.5 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Laminin_II PF06009.12 ORZ03862.1 - 7 6.7 10.1 21 5.1 4.1 2.9 2 1 0 2 2 2 0 Laminin Domain II HIP1_clath_bdg PF16515.5 ORZ03862.1 - 7.9 7.2 20.9 3.7 8.2 1.1 3.9 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PH PF00169.29 ORZ03863.1 - 1.9e-45 153.7 3.1 9.4e-22 77.5 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 ORZ03863.1 - 1.9e-16 60.4 10.3 7.2e-08 32.8 5.6 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 ORZ03863.1 - 1.7e-14 53.8 3.2 7.6e-07 29.3 2.3 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 ORZ03863.1 - 5.4e-13 48.9 4.6 1.2e-07 31.8 2.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 ORZ03863.1 - 8.9e-07 29.3 4.3 0.0075 16.6 2.8 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain Myosin_TH1 PF06017.13 ORZ03863.1 - 9.7e-05 22.1 0.1 0.054 13.2 0.1 2.3 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding PH_13 PF16652.5 ORZ03863.1 - 0.00017 21.4 0.9 0.037 13.9 0.6 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 ORZ03863.1 - 0.00052 20.1 1.0 0.3 11.2 0.5 2.7 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.10 ORZ03863.1 - 0.037 14.4 0.3 0.19 12.1 0.6 2.0 2 0 0 2 2 2 0 Plant pleckstrin homology-like region BCL_N PF04714.13 ORZ03863.1 - 0.067 13.3 4.8 0.99 9.5 1.5 2.6 2 0 0 2 2 2 0 BCL7, N-terminal conserver region DUF3673 PF12425.8 ORZ03863.1 - 0.12 12.3 1.7 33 4.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3673) PH_4 PF15404.6 ORZ03863.1 - 0.37 10.6 8.4 1.7 8.4 0.1 3.9 3 2 1 4 4 4 0 Pleckstrin homology domain HMG_box PF00505.19 ORZ03864.1 - 7e-20 71.2 0.3 1.1e-19 70.6 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ03864.1 - 2e-09 37.9 0.1 4.6e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain XPG_N PF00752.17 ORZ03865.1 - 2.2e-38 130.8 0.0 4.5e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORZ03865.1 - 4.4e-30 103.9 0.0 1e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 ORZ03865.1 - 2.3e-06 28.1 0.0 1.5e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 ORZ03865.1 - 0.0085 16.7 0.0 0.024 15.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 ORZ03865.1 - 0.024 14.7 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-C2H2 PF00096.26 ORZ03866.1 - 2.2e-08 34.1 27.7 0.0002 21.6 5.8 4.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ03866.1 - 5.4e-08 32.9 14.2 0.021 15.2 1.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORZ03866.1 - 4.9e-06 26.4 6.8 0.00022 21.1 1.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORZ03866.1 - 9.9e-06 26.0 22.7 0.003 18.3 2.8 4.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf_UBZ PF18439.1 ORZ03866.1 - 0.0073 15.9 1.3 2.3 7.9 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 ORZ03866.1 - 0.13 12.6 0.5 0.13 12.6 0.5 4.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 ORZ03866.1 - 0.67 10.2 6.2 1.7 9.0 1.4 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain CDC45 PF02724.14 ORZ03866.1 - 2.7 6.2 11.2 3.3 5.9 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PRIMA1 PF16101.5 ORZ03867.1 - 0.1 12.6 1.0 0.14 12.2 1.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 ORZ03867.1 - 0.19 11.2 3.5 0.25 10.8 3.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal A2M_BRD PF07703.14 ORZ03867.1 - 0.2 12.0 0.0 0.27 11.6 0.0 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin bait region domain RabGAP-TBC PF00566.18 ORZ03868.1 - 7.7e-25 87.8 0.1 9.9e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Aminotran_3 PF00202.21 ORZ03869.1 - 2.2e-119 398.8 0.0 2.7e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORZ03869.1 - 0.00022 20.5 0.0 0.00063 19.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3591 PF12157.8 ORZ03870.1 - 4.6e-178 592.4 0.0 8.5e-178 591.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) TBP-binding PF09247.11 ORZ03870.1 - 7.1e-10 39.0 0.2 2e-09 37.5 0.2 1.8 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 ORZ03870.1 - 3.4e-07 30.0 1.9 7.8e-07 28.8 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle LZ_Tnp_IS66 PF13007.7 ORZ03870.1 - 0.26 12.1 0.1 0.26 12.1 0.1 3.9 4 1 0 4 4 4 0 Transposase C of IS166 homeodomain zf-CCHC PF00098.23 ORZ03870.1 - 0.32 11.2 2.8 0.69 10.1 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF733 PF05306.11 ORZ03870.1 - 2.5 8.5 9.8 2.4 8.5 3.9 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF733) SSB PF00436.25 ORZ03871.1 - 1.3e-26 92.6 0.1 1.6e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 ORZ03871.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ABC_tran PF00005.27 ORZ03872.1 - 7e-25 88.1 0.0 1.2e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORZ03872.1 - 4.4e-06 26.7 0.1 0.033 14.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ORZ03872.1 - 0.00023 20.8 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORZ03872.1 - 0.00026 20.8 0.0 0.0038 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORZ03872.1 - 0.00033 21.1 0.1 0.00046 20.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ORZ03872.1 - 0.00053 19.5 0.0 0.0019 17.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORZ03872.1 - 0.0032 17.7 0.0 0.0053 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORZ03872.1 - 0.0048 16.6 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORZ03872.1 - 0.0054 17.3 3.5 0.13 12.9 3.3 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORZ03872.1 - 0.0086 15.5 0.0 0.07 12.5 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORZ03872.1 - 0.011 15.7 0.1 0.035 14.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 ORZ03872.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 ORZ03872.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.6 ORZ03872.1 - 0.023 14.9 0.2 0.52 10.6 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ORZ03872.1 - 0.03 14.8 0.1 0.087 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 ORZ03872.1 - 0.04 13.1 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_28 PF13521.6 ORZ03872.1 - 0.053 13.8 0.4 0.053 13.8 0.4 1.9 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 ORZ03872.1 - 0.06 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 ORZ03872.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 ORZ03872.1 - 0.1 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORZ03872.1 - 0.17 12.0 1.3 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 ORZ03873.1 - 1.2e-50 172.4 0.0 1.8e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03873.1 - 4.1e-18 65.6 0.0 6.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORZ03873.1 - 0.0072 15.7 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORZ03873.1 - 0.029 13.2 4.6 0.11 11.3 4.2 1.9 1 1 0 1 1 1 0 Fungal protein kinase PepSY_TM_like_2 PF16357.5 ORZ03873.1 - 0.04 13.9 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF4451 PF14616.6 ORZ03874.1 - 3.9e-16 59.4 3.5 7.8e-16 58.4 3.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) zinc_ribbon_9 PF14369.6 ORZ03874.1 - 0.035 14.4 4.2 0.18 12.1 1.2 2.5 2 0 0 2 2 2 0 zinc-ribbon DUF5318 PF17249.2 ORZ03874.1 - 0.041 13.6 0.3 0.13 12.0 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5318) WD40 PF00400.32 ORZ03875.1 - 5e-41 137.9 26.4 3.1e-06 27.8 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 ORZ03875.1 - 2.9e-13 49.3 7.5 0.038 12.6 0.0 5.3 3 2 2 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.33 ORZ03875.1 - 2.3e-08 33.7 0.6 4.5e-08 32.8 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORZ03875.1 - 2.1e-07 30.7 0.6 4.1e-07 29.8 0.6 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORZ03875.1 - 8.8e-07 29.1 1.6 0.56 10.5 0.0 5.5 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORZ03875.1 - 1.5e-06 27.8 0.0 2.9e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 WD40-like domain PQQ_2 PF13360.6 ORZ03875.1 - 7.4e-05 22.4 4.4 0.028 14.0 0.2 3.2 2 1 1 3 3 3 2 PQQ-like domain PALB2_WD40 PF16756.5 ORZ03875.1 - 0.0006 18.8 1.1 3.2 6.6 0.0 4.3 1 1 2 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 ORZ03875.1 - 0.007 15.4 1.7 1.7 7.6 0.0 3.5 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Aminotran_4 PF01063.19 ORZ03876.1 - 4.5e-20 72.5 0.0 7.9e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV Asn_synthase PF00733.21 ORZ03877.1 - 9.7e-21 74.8 0.0 1e-17 64.9 0.0 2.3 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ORZ03877.1 - 3.6e-11 43.0 0.0 2.7e-10 40.2 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORZ03877.1 - 2.3e-06 27.8 0.0 8.6e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DNA_pol_B PF00136.21 ORZ03878.1 - 1.5e-121 406.3 1.1 1.9e-121 406.0 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 ORZ03878.1 - 8.4e-56 188.6 10.5 1.5e-55 187.8 10.5 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 ORZ03878.1 - 4.1e-50 170.8 0.0 7.6e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 ORZ03878.1 - 6.5e-06 26.1 9.7 3.6e-05 23.8 9.7 2.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 ORZ03878.1 - 0.0021 17.0 0.0 0.0045 15.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 ORZ03878.1 - 0.018 13.6 0.1 0.033 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) ARPC4 PF05856.12 ORZ03878.1 - 0.13 11.9 2.0 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Cytochrom_c3_2 PF14537.6 ORZ03878.1 - 1.2 9.7 5.0 3.7 8.1 5.0 1.8 1 0 0 1 1 1 0 Cytochrome c3 MFS_1 PF07690.16 ORZ03879.1 - 4.3e-39 134.4 32.3 5.1e-39 134.2 32.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 ORZ03879.1 - 0.036 14.5 0.3 0.14 12.5 0.3 2.0 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 UNC-93 PF05978.16 ORZ03879.1 - 0.58 9.9 12.1 0.045 13.5 4.6 2.6 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Atg29_N PF18388.1 ORZ03881.1 - 3.1e-16 58.9 0.6 5.4e-16 58.2 0.6 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain Myb_DNA-bind_6 PF13921.6 ORZ03881.1 - 0.0065 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DKCLD PF08068.12 ORZ03882.1 - 2.3e-35 120.5 0.1 1.4e-33 114.8 0.2 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 ORZ03882.1 - 3.1e-23 82.8 0.2 1.5e-20 74.1 0.2 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ORZ03882.1 - 2.5e-22 78.8 0.8 4.5e-22 78.0 0.8 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 ORZ03882.1 - 9.8e-19 67.1 0.8 1.9e-18 66.2 0.8 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 ORZ03882.1 - 0.057 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain MFS_1 PF07690.16 ORZ03883.1 - 3.3e-50 171.0 45.0 1.9e-47 161.9 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORZ03883.1 - 1.5e-08 34.0 30.2 1.2e-07 31.0 12.7 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 ORZ03883.1 - 0.047 12.0 6.1 2.2 6.5 2.5 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 ORZ03883.1 - 3.2 6.5 23.7 2.1 7.1 9.5 3.1 3 0 0 3 3 3 0 MFS_1 like family AMPK1_CBM PF16561.5 ORZ03884.1 - 4.5e-34 116.5 0.4 8.2e-34 115.7 0.4 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 ORZ03884.1 - 2.1e-27 95.2 4.7 2.1e-27 95.2 4.7 2.6 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 ORZ03884.1 - 0.0027 18.0 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 ORZ03884.1 - 0.0041 17.7 0.1 0.012 16.1 0.1 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-HC5HC2H_2 PF13832.6 ORZ03885.1 - 7e-32 109.9 9.7 7e-32 109.9 9.7 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 ORZ03885.1 - 5e-30 105.0 0.2 5e-30 105.0 0.2 4.4 3 2 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 ORZ03885.1 - 1.1e-25 89.7 7.8 1.1e-25 89.7 7.8 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 ORZ03885.1 - 1.5e-14 53.3 2.6 1.5e-14 53.3 2.6 2.6 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.25 ORZ03885.1 - 1.8e-14 53.6 0.3 3.8e-14 52.5 0.3 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 ORZ03885.1 - 1.7e-09 37.4 8.7 1.7e-09 37.4 8.7 2.8 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 ORZ03885.1 - 3.4e-07 30.6 0.7 3.4e-07 30.6 0.7 3.4 3 1 0 3 3 3 1 PWWP domain zf-PHD-like PF15446.6 ORZ03885.1 - 0.012 15.3 2.2 0.012 15.3 2.2 3.2 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 ORZ03885.1 - 0.015 15.1 0.7 0.015 15.1 0.7 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 ORZ03885.1 - 3.9 7.9 18.5 8.8 6.7 4.5 2.8 2 0 0 2 2 2 0 C1 domain TPR_1 PF00515.28 ORZ03886.1 - 6.5e-09 35.2 4.5 0.004 16.9 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORZ03886.1 - 8e-08 32.5 4.4 0.031 14.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORZ03886.1 - 1.2e-07 31.2 5.6 0.014 15.5 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 ORZ03886.1 - 2.5e-07 30.4 1.1 9.4e-07 28.6 0.3 2.4 3 0 0 3 3 3 1 UBA/TS-N domain TPR_8 PF13181.6 ORZ03886.1 - 0.0032 17.5 3.3 8.6 6.9 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORZ03886.1 - 0.0044 17.0 3.2 0.69 10.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORZ03886.1 - 0.01 15.5 0.6 4.6 7.0 0.1 3.2 3 1 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 ORZ03886.1 - 0.02 15.4 6.0 4.4 7.9 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DnaJ PF00226.31 ORZ03886.1 - 0.034 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 DnaJ domain TPR_16 PF13432.6 ORZ03886.1 - 0.54 10.9 9.2 0.081 13.6 1.8 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORZ03886.1 - 0.82 10.7 14.6 0.95 10.5 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Apc13p PF05839.11 ORZ03887.1 - 0.069 13.4 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Apc13p protein Pkinase PF00069.25 ORZ03889.1 - 1.1e-29 103.6 0.1 1.8e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03889.1 - 2.2e-08 33.7 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RNase_P_pop3 PF08228.11 ORZ03890.1 - 3e-11 43.6 0.0 1.1e-10 41.8 0.1 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.26 ORZ03890.1 - 0.021 14.5 0.0 0.06 13.1 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Vps53_N PF04100.12 ORZ03891.1 - 9.8e-112 373.7 5.5 1.7e-111 372.9 5.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 ORZ03891.1 - 2.1e-08 33.8 10.3 4.2e-08 32.8 5.8 2.6 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 ORZ03891.1 - 4.4e-06 25.8 9.3 9.2e-06 24.7 9.3 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein VPS53_C PF16854.5 ORZ03891.1 - 0.0015 18.5 0.0 0.029 14.2 0.0 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus TSP9 PF11493.8 ORZ03891.1 - 0.053 14.2 0.0 0.7 10.6 0.0 2.3 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 VasL PF12486.8 ORZ03891.1 - 0.081 12.8 6.6 0.076 12.9 1.9 2.7 1 1 1 2 2 2 0 Type VI secretion system, EvfB, or VasL DUF2203 PF09969.9 ORZ03891.1 - 0.82 10.4 5.6 2.7 8.7 1.9 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 ORZ03891.1 - 2.7 8.3 6.3 1.7 8.9 3.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cys_Met_Meta_PP PF01053.20 ORZ03893.1 - 1.9e-135 451.3 0.0 2.2e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 ORZ03893.1 - 0.00034 19.3 0.0 0.00075 18.1 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 ORZ03893.1 - 0.00072 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORZ03893.1 - 0.00082 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II ABC2_membrane PF01061.24 ORZ03894.1 - 1.3e-76 256.7 60.2 4.3e-43 147.2 22.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORZ03894.1 - 1.4e-37 129.3 0.0 1.7e-21 77.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORZ03894.1 - 4.6e-26 90.6 13.0 1.9e-19 69.3 0.0 4.1 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORZ03894.1 - 1.9e-13 50.8 0.0 4.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 ORZ03894.1 - 2.2e-06 28.2 0.0 0.0017 18.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ORZ03894.1 - 2.3e-05 24.4 0.0 0.056 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORZ03894.1 - 0.00018 21.4 0.5 0.0072 16.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 ORZ03894.1 - 0.0014 17.8 9.3 0.0014 17.8 9.3 2.9 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.6 ORZ03894.1 - 0.0022 17.7 0.4 0.019 14.7 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORZ03894.1 - 0.0096 16.5 0.1 0.09 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORZ03894.1 - 0.013 15.1 0.3 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORZ03894.1 - 0.037 13.7 0.3 2.4 7.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORZ03894.1 - 0.042 14.1 0.1 0.72 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORZ03894.1 - 0.045 13.9 0.1 0.55 10.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORZ03894.1 - 0.084 13.1 0.3 0.77 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 ORZ03894.1 - 0.18 11.4 0.3 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORZ03894.1 - 0.25 11.5 0.5 9.9 6.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 ORZ03894.1 - 0.32 10.2 11.6 0.45 9.8 2.8 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein Nipped-B_C PF12830.7 ORZ03895.1 - 7.8e-39 133.6 0.0 8.4e-38 130.2 0.0 2.7 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT PF02985.22 ORZ03895.1 - 5.7e-05 23.0 0.6 2.2 8.7 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 ORZ03895.1 - 0.0024 18.0 0.9 0.012 15.7 0.1 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORZ03895.1 - 0.0084 14.7 0.4 0.06 11.9 0.1 2.3 2 1 1 3 3 3 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 ORZ03895.1 - 0.0093 16.3 1.3 0.9 9.9 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 ORZ03895.1 - 0.011 16.1 3.2 0.088 13.2 0.0 3.8 4 1 1 5 5 5 0 HEAT repeats BicD PF09730.9 ORZ03896.1 - 7.3e-05 21.4 17.8 0.00099 17.7 17.7 1.9 1 1 0 1 1 1 1 Microtubule-associated protein Bicaudal-D XhlA PF10779.9 ORZ03896.1 - 0.00012 22.2 17.0 0.063 13.5 4.4 3.3 2 1 1 3 3 3 2 Haemolysin XhlA GOLGA2L5 PF15070.6 ORZ03896.1 - 0.00018 20.3 16.2 0.00024 19.9 16.2 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF1664 PF07889.12 ORZ03896.1 - 0.0002 21.4 9.0 0.048 13.7 6.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) GAS PF13851.6 ORZ03896.1 - 0.00065 19.1 21.8 0.081 12.3 12.9 2.2 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 ORZ03896.1 - 0.00095 19.5 23.8 0.35 11.2 9.7 5.0 2 2 2 4 4 4 1 Csm1 N-terminal domain HR1 PF02185.16 ORZ03896.1 - 0.0017 18.4 22.0 0.049 13.8 9.2 3.7 2 2 1 3 3 3 2 Hr1 repeat Med9 PF07544.13 ORZ03896.1 - 0.0044 17.1 18.4 0.098 12.8 12.4 2.8 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.11 ORZ03896.1 - 0.0056 16.5 20.3 0.03 14.1 1.7 2.5 1 1 0 2 2 2 1 Phage minor structural protein GP20 Spc7 PF08317.11 ORZ03896.1 - 0.0078 15.1 23.5 0.059 12.3 15.4 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF16 PF01519.16 ORZ03896.1 - 0.011 16.2 15.7 0.037 14.5 10.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 ORZ03896.1 - 0.011 16.2 11.7 0.23 12.0 2.4 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein YvrJ PF12841.7 ORZ03896.1 - 0.013 15.0 5.1 1.5 8.4 0.5 2.8 2 0 0 2 2 2 0 YvrJ protein family DUF5082 PF16888.5 ORZ03896.1 - 0.014 15.6 9.7 0.014 15.6 9.7 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Spc24 PF08286.11 ORZ03896.1 - 0.029 14.6 17.6 0.19 12.0 0.9 3.0 2 2 0 2 2 2 0 Spc24 subunit of Ndc80 Troponin PF00992.20 ORZ03896.1 - 0.03 14.6 7.3 0.03 14.6 7.3 2.8 1 1 2 3 3 3 0 Troponin Baculo_PEP_C PF04513.12 ORZ03896.1 - 0.03 14.4 6.4 0.87 9.6 1.6 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 ORZ03896.1 - 0.031 14.4 2.5 0.031 14.4 2.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 ORZ03896.1 - 0.041 13.9 29.2 0.54 10.3 3.5 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF4600 PF15372.6 ORZ03896.1 - 0.048 14.1 13.1 0.13 12.7 12.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Atg14 PF10186.9 ORZ03896.1 - 0.055 12.6 20.1 0.052 12.6 5.0 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 ORZ03896.1 - 0.059 13.8 10.2 12 6.3 1.6 4.1 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 ORZ03896.1 - 0.081 13.3 19.5 0.61 10.5 9.7 3.4 2 2 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Occludin_ELL PF07303.13 ORZ03896.1 - 0.098 13.4 12.8 0.21 12.3 2.0 2.3 1 1 1 2 2 2 0 Occludin homology domain Exonuc_VII_L PF02601.15 ORZ03896.1 - 0.11 12.1 14.3 0.16 11.5 14.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit NRBF2 PF08961.10 ORZ03896.1 - 0.13 11.8 16.1 2.4 7.7 0.4 2.7 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ALIX_LYPXL_bnd PF13949.6 ORZ03896.1 - 0.14 11.4 15.6 9.6 5.4 9.7 2.4 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4795 PF16043.5 ORZ03896.1 - 0.15 11.6 20.8 0.26 10.9 6.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) BRE1 PF08647.11 ORZ03896.1 - 0.16 12.1 22.2 0.15 12.2 13.1 2.4 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase ABC_tran_CTD PF16326.5 ORZ03896.1 - 0.17 12.2 25.3 1.8 8.9 10.8 3.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain HOOK PF05622.12 ORZ03896.1 - 0.19 9.8 23.1 0.47 8.5 15.8 2.0 1 1 1 2 2 2 0 HOOK protein MCPsignal PF00015.21 ORZ03896.1 - 0.21 11.4 5.0 0.27 11.0 1.8 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Nup54 PF13874.6 ORZ03896.1 - 0.23 11.6 17.4 0.98 9.5 1.0 2.7 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Tropomyosin_1 PF12718.7 ORZ03896.1 - 0.24 11.6 24.1 1.2 9.3 15.3 2.3 1 1 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.9 ORZ03896.1 - 0.24 11.7 15.2 1 9.7 8.4 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 ORZ03896.1 - 0.24 11.5 25.9 10 6.2 18.2 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 ORZ03896.1 - 0.32 11.4 13.0 3.9 7.9 4.4 2.9 1 1 2 3 3 3 0 Syntaxin-like protein HAUS-augmin3 PF14932.6 ORZ03896.1 - 0.34 10.4 20.4 0.038 13.6 12.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2524 PF10732.9 ORZ03896.1 - 0.39 11.1 13.1 0.28 11.5 7.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) APG6_N PF17675.1 ORZ03896.1 - 0.39 11.2 29.0 0.22 12.1 3.1 2.4 1 1 0 2 2 2 0 Apg6 coiled-coil region TRAF_BIRC3_bd PF16673.5 ORZ03896.1 - 0.4 10.5 9.5 4.5 7.1 0.4 2.8 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Sec8_exocyst PF04048.14 ORZ03896.1 - 0.45 10.4 12.2 1.2 9.0 4.8 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain FapA PF03961.13 ORZ03896.1 - 0.45 9.1 15.9 0.31 9.6 9.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A ACCA PF03255.14 ORZ03896.1 - 0.47 10.3 12.6 0.15 11.9 5.1 2.5 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_DNA_bd PF12329.8 ORZ03896.1 - 0.48 10.5 24.9 0.5 10.4 1.3 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.8 ORZ03896.1 - 0.48 7.9 21.8 0.087 10.3 16.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 ORZ03896.1 - 0.6 10.5 19.4 0.27 11.6 11.9 2.1 1 1 1 2 2 2 0 Fez1 Jnk-SapK_ap_N PF09744.9 ORZ03896.1 - 0.71 10.1 23.3 2.3 8.4 1.6 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CorA PF01544.18 ORZ03896.1 - 0.77 9.0 7.4 1.5 8.0 7.4 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TSC22 PF01166.18 ORZ03896.1 - 0.79 10.1 11.6 9 6.7 0.1 4.0 4 1 2 6 6 4 0 TSC-22/dip/bun family CC2-LZ PF16516.5 ORZ03896.1 - 0.93 9.9 21.1 0.58 10.6 1.6 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Phage_GPO PF05929.11 ORZ03896.1 - 1 9.0 17.8 0.17 11.5 8.9 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Prefoldin_2 PF01920.20 ORZ03896.1 - 1 9.3 23.3 10 6.1 2.9 3.4 1 1 1 2 2 2 0 Prefoldin subunit Shugoshin_N PF07558.11 ORZ03896.1 - 1.2 9.1 8.8 11 6.0 0.5 3.9 4 0 0 4 4 3 0 Shugoshin N-terminal coiled-coil region Lectin_N PF03954.14 ORZ03896.1 - 1.2 8.9 11.6 1.8 8.3 4.5 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF5344 PF17279.2 ORZ03896.1 - 1.2 9.8 11.4 0.1 13.2 3.9 2.7 3 1 0 3 3 2 0 Family of unknown function (DUF5344) DUF3450 PF11932.8 ORZ03896.1 - 1.2 8.4 22.2 2.9 7.1 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAP206 PF12018.8 ORZ03896.1 - 1.2 8.5 11.2 0.17 11.3 2.2 2.7 1 1 1 3 3 3 0 Domain of unknown function DUF3987 PF13148.6 ORZ03896.1 - 1.3 7.9 14.4 1.1 8.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF4404 PF14357.6 ORZ03896.1 - 1.4 9.6 21.7 6.4 7.5 2.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) PCRF PF03462.18 ORZ03896.1 - 1.4 8.8 14.7 0.1 12.5 6.8 2.3 1 1 2 3 3 3 0 PCRF domain TssO PF17561.2 ORZ03896.1 - 1.4 9.0 10.8 19 5.3 2.1 3.6 1 1 3 4 4 4 0 Type VI secretion system, TssO Laminin_II PF06009.12 ORZ03896.1 - 1.4 8.9 15.2 2.8 8.0 1.1 2.4 2 1 0 2 2 2 0 Laminin Domain II FlxA PF14282.6 ORZ03896.1 - 1.5 8.8 26.2 6 6.9 8.9 3.4 1 1 3 4 4 4 0 FlxA-like protein LXG PF04740.12 ORZ03896.1 - 1.6 8.4 16.7 0.34 10.6 10.6 2.2 1 1 0 2 2 2 0 LXG domain of WXG superfamily DUF4472 PF14739.6 ORZ03896.1 - 1.6 9.5 20.2 5.1 7.9 8.6 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DivIC PF04977.15 ORZ03896.1 - 1.7 8.5 25.3 1.2 9.0 2.6 3.9 2 1 1 3 3 3 0 Septum formation initiator CSN5_C PF18323.1 ORZ03896.1 - 1.9 9.5 12.4 0.41 11.6 0.6 2.5 1 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Utp12 PF04003.12 ORZ03896.1 - 1.9 8.8 7.8 5.8 7.3 0.4 3.2 1 1 2 3 3 3 0 Dip2/Utp12 Family CENP-K PF11802.8 ORZ03896.1 - 1.9 8.0 16.0 3.1 7.3 16.0 1.3 1 1 0 1 1 1 0 Centromere-associated protein K DUF2203 PF09969.9 ORZ03896.1 - 2.4 8.9 14.6 3.1e+02 2.1 14.6 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 ORZ03896.1 - 2.5 8.7 14.0 2.4e+02 2.4 14.0 3.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HALZ PF02183.18 ORZ03896.1 - 2.6 8.4 14.7 0.25 11.6 0.9 3.6 5 0 0 5 5 2 0 Homeobox associated leucine zipper FUSC PF04632.12 ORZ03896.1 - 2.8 6.4 9.5 4 5.9 9.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family YojJ PF10372.9 ORZ03896.1 - 2.8 8.1 9.2 1.7 8.8 2.1 3.0 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus TMF_TATA_bd PF12325.8 ORZ03896.1 - 3 8.1 18.9 18 5.6 11.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin PF02996.17 ORZ03896.1 - 3 7.8 18.7 3.1 7.7 3.8 3.4 2 1 1 3 3 3 0 Prefoldin subunit DUF724 PF05266.14 ORZ03896.1 - 3 7.6 18.8 5.3 6.8 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 ORZ03896.1 - 3.2 6.9 17.4 6 6.0 0.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein betaPIX_CC PF16523.5 ORZ03896.1 - 3.4 7.6 14.7 0.54 10.1 4.0 3.0 1 1 2 3 3 3 0 betaPIX coiled coil CENP-H PF05837.12 ORZ03896.1 - 3.4 8.1 21.1 0.5 10.8 1.9 2.2 1 1 0 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 ORZ03896.1 - 3.8 6.3 10.9 5.2 5.9 10.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 ORZ03896.1 - 3.8 6.8 21.6 28 3.9 21.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 ORZ03896.1 - 4.1 7.9 22.2 27 5.3 6.5 3.7 1 1 1 2 2 2 0 Cell division protein ZapB Val_tRNA-synt_C PF10458.9 ORZ03896.1 - 4.1 7.7 17.1 7 7.0 0.8 4.5 4 1 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Uds1 PF15456.6 ORZ03896.1 - 4.5 7.4 20.2 26 5.0 12.1 3.0 1 1 1 2 2 2 0 Up-regulated During Septation Cob_adeno_trans PF01923.18 ORZ03896.1 - 4.6 7.4 11.0 7.5 6.7 5.9 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Swi5 PF07061.11 ORZ03896.1 - 5.2 7.2 19.4 6.3 7.0 1.7 3.5 2 2 0 2 2 2 0 Swi5 Phage_Nu1 PF07471.12 ORZ03896.1 - 5.3 6.8 8.8 0.98 9.2 4.2 1.9 1 1 1 2 2 2 0 Phage DNA packaging protein Nu1 AAA_13 PF13166.6 ORZ03896.1 - 5.4 5.5 18.9 2.5 6.7 1.3 2.3 1 1 0 2 2 2 0 AAA domain T2SSM PF04612.12 ORZ03896.1 - 5.6 7.0 12.9 4.5 7.3 0.8 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M Fzo_mitofusin PF04799.13 ORZ03896.1 - 5.9 6.4 17.1 1.4 8.4 6.9 3.1 1 1 2 3 3 3 0 fzo-like conserved region DUF2175 PF09943.9 ORZ03896.1 - 5.9 7.3 8.8 3 8.2 1.5 2.8 1 1 2 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2175) V_ATPase_I PF01496.19 ORZ03896.1 - 6.5 4.5 15.1 4 5.2 8.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.8 ORZ03896.1 - 7 6.2 24.8 4.4 6.9 3.1 3.1 1 1 0 3 3 3 0 Protein of unknown function (DUF2968) ERM PF00769.19 ORZ03896.1 - 7.4 6.3 25.9 0.79 9.5 16.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Allexi_40kDa PF05549.11 ORZ03896.1 - 8.8 5.8 13.1 12 5.4 7.1 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Prominin PF05478.11 ORZ03896.1 - 8.8 4.1 10.0 21 2.9 10.0 1.5 1 1 0 1 1 1 0 Prominin DUF2721 PF11026.8 ORZ03896.1 - 8.9 6.2 6.0 1.9 8.4 0.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) Flagellin_N PF00669.20 ORZ03896.1 - 9 6.4 12.3 3.9 7.6 6.0 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region GRAB PF10375.9 ORZ03897.1 - 2.3e-08 33.6 0.5 6.2e-08 32.2 0.5 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Cauli_AT PF03233.13 ORZ03897.1 - 0.0041 17.1 4.3 0.0041 17.1 4.3 3.6 2 2 1 4 4 4 1 Aphid transmission protein ADIP PF11559.8 ORZ03897.1 - 0.01 15.9 23.2 0.01 15.9 23.2 5.1 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding Med9 PF07544.13 ORZ03897.1 - 0.013 15.6 9.2 0.013 15.6 9.2 5.7 3 2 3 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 GRIP PF01465.20 ORZ03897.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 GRIP domain Spc7 PF08317.11 ORZ03897.1 - 0.38 9.6 71.4 0.0078 15.1 24.9 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 ORZ03897.1 - 1.6 8.8 39.8 0.45 10.6 7.3 4.4 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Glucan_synthase PF02364.15 ORZ03898.1 - 0 1289.6 0.0 0 1289.0 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORZ03898.1 - 3.2e-32 111.6 2.2 2e-30 105.8 2.2 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Forkhead PF00250.18 ORZ03899.1 - 3.8e-33 113.6 0.1 7.5e-33 112.6 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain PRIMA1 PF16101.5 ORZ03899.1 - 0.25 11.4 3.7 0.72 9.9 3.7 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3177 PF11375.8 ORZ03900.1 - 0.082 12.7 0.7 0.13 12.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Transketolase_N PF00456.21 ORZ03901.1 - 2e-148 493.8 0.0 2.6e-148 493.4 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORZ03901.1 - 3.1e-39 134.5 0.0 1.9e-38 131.9 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORZ03901.1 - 1.1e-09 38.2 0.0 4.7e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORZ03901.1 - 0.00014 21.2 0.0 0.0003 20.1 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ORZ03901.1 - 0.0077 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ThiP_synth PF10120.9 ORZ03901.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine-phosphate synthase HEAT PF02985.22 ORZ03902.1 - 4.6e-44 144.7 19.1 0.00058 19.9 0.1 14.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 ORZ03902.1 - 3.6e-35 120.2 11.9 2.5e-08 34.2 0.0 8.0 4 4 2 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 ORZ03902.1 - 1.7e-09 38.0 9.6 0.14 12.7 0.2 7.8 8 1 1 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORZ03902.1 - 3.5e-09 37.1 0.0 1.8 9.2 0.0 6.3 4 3 3 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORZ03902.1 - 3.5e-08 33.7 3.3 0.042 13.9 0.0 4.4 3 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORZ03902.1 - 2.9e-05 22.8 4.8 0.26 9.8 0.0 4.0 3 1 1 4 4 4 2 Adaptin N terminal region Arm PF00514.23 ORZ03902.1 - 0.0031 17.5 0.7 6.4 7.0 0.1 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 ORZ03902.1 - 0.0097 16.5 0.9 18 6.4 0.0 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Ecm29 PF13001.7 ORZ03902.1 - 0.028 13.1 4.8 1.8 7.2 0.0 4.1 4 2 1 5 5 5 0 Proteasome stabiliser DUF4042 PF13251.6 ORZ03902.1 - 0.043 13.5 0.4 1 9.0 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.7 ORZ03902.1 - 0.093 13.1 0.3 3.1 8.2 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion API5 PF05918.11 ORZ03902.1 - 0.16 10.8 1.8 47 2.6 0.0 4.2 6 0 0 6 6 6 0 Apoptosis inhibitory protein 5 (API5) Mlh1_C PF16413.5 ORZ03903.1 - 1.6e-74 250.7 0.0 3.1e-74 249.8 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 ORZ03903.1 - 2.9e-32 110.8 0.6 5.3e-32 110.0 0.6 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORZ03903.1 - 1.3e-13 50.9 0.0 1.3e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORZ03903.1 - 3.2e-05 24.4 0.0 7.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nuc_sug_transp PF04142.15 ORZ03904.1 - 9.6e-109 363.3 8.8 1.1e-108 363.2 8.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 ORZ03904.1 - 1.2e-09 38.5 24.7 2.2e-07 31.1 3.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORZ03904.1 - 1.6e-06 27.6 10.2 2.5e-06 26.9 10.2 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 ORZ03904.1 - 0.00022 20.3 2.6 0.00022 20.3 2.6 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 ORZ03904.1 - 0.00023 20.9 0.5 0.00023 20.9 0.5 2.1 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter UAA PF08449.11 ORZ03904.1 - 0.00064 19.0 12.1 0.00097 18.4 11.5 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 ORZ03904.1 - 0.0031 16.9 1.4 0.0031 16.9 1.4 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF2070 PF09843.9 ORZ03904.1 - 0.018 13.4 8.0 0.026 12.8 8.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SLC3A2_N PF16028.5 ORZ03904.1 - 1 9.0 0.0 1 9.0 0.0 2.6 4 0 0 4 4 4 0 Solute carrier family 3 member 2 N-terminus F-box-like PF12937.7 ORZ03905.1 - 5.4e-09 35.8 2.8 1.2e-08 34.7 1.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORZ03905.1 - 1.6e-08 34.2 0.9 5.1e-08 32.6 0.9 1.9 1 0 0 1 1 1 1 F-box domain Ribosomal_L13 PF00572.18 ORZ03906.1 - 6.1e-55 184.8 0.1 7.1e-55 184.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 NDK PF00334.19 ORZ03907.1 - 7.6e-38 129.6 0.1 2.8e-37 127.7 0.0 1.9 2 0 0 2 2 2 1 Nucleoside diphosphate kinase ACOX PF01756.19 ORZ03908.1 - 9.4e-47 158.9 0.3 9.4e-47 158.9 0.3 2.0 2 1 1 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORZ03908.1 - 7.3e-29 100.9 0.0 1.4e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORZ03908.1 - 5.4e-13 49.0 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORZ03908.1 - 0.0013 19.0 0.8 0.01 16.0 0.8 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORZ03908.1 - 0.097 13.3 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain WD40 PF00400.32 ORZ03909.1 - 4.3e-29 100.2 11.1 7.9e-06 26.5 0.5 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORZ03909.1 - 5.7e-12 45.8 1.2 0.00031 21.0 0.0 4.5 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORZ03909.1 - 0.00014 21.8 0.0 0.0067 16.3 0.0 2.7 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORZ03909.1 - 0.00042 19.7 0.0 0.0021 17.5 0.0 2.0 1 1 0 1 1 1 1 WD40-like domain HPS3_N PF14761.6 ORZ03909.1 - 0.07 12.7 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 DUF4221 PF13970.6 ORZ03909.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) ArfGap PF01412.18 ORZ03910.1 - 9.2e-25 87.0 0.0 1.4e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 ORZ03910.1 - 0.021 14.4 0.3 0.033 13.7 0.3 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding TFIIA PF03153.13 ORZ03911.1 - 9.7e-62 210.3 39.1 2.5e-39 136.4 36.9 3.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 ORZ03911.1 - 0.054 11.8 16.1 0.07 11.4 16.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 ORZ03911.1 - 2.1 9.0 19.0 3.7 8.2 19.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4051 PF13260.6 ORZ03912.1 - 0.073 12.8 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) TRAP_alpha PF03896.16 ORZ03912.1 - 0.091 12.0 4.3 0.25 10.5 3.4 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CNDH2_C PF16858.5 ORZ03912.1 - 0.11 12.3 5.4 0.2 11.5 5.4 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 ORZ03912.1 - 4.3 5.3 18.8 6.3 4.8 18.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 ORZ03912.1 - 6.6 6.7 8.2 0.35 10.9 1.8 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Pyr_redox_2 PF07992.14 ORZ03913.1 - 1.9e-50 171.8 0.5 2.2e-50 171.6 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORZ03913.1 - 1.1e-18 67.6 0.6 5.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORZ03913.1 - 3.8e-15 56.2 0.3 1.9e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORZ03913.1 - 1.4e-06 27.8 0.9 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ORZ03913.1 - 0.00026 20.4 0.2 0.041 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ORZ03913.1 - 0.00034 19.9 0.1 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ORZ03913.1 - 0.0005 20.2 0.3 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 ORZ03913.1 - 0.0013 19.1 0.1 0.07 13.6 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 ORZ03913.1 - 0.0028 17.3 1.9 1.7 8.2 0.0 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 ORZ03913.1 - 0.0045 16.1 4.1 0.33 10.0 0.3 3.7 3 1 1 4 4 4 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORZ03913.1 - 0.013 14.3 2.3 0.071 11.8 0.2 2.9 3 1 1 4 4 4 0 HI0933-like protein K_oxygenase PF13434.6 ORZ03913.1 - 0.023 13.8 0.4 0.18 10.9 0.1 2.5 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 ORZ03913.1 - 0.063 12.1 0.3 0.49 9.2 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 ORZ03913.1 - 0.14 11.3 4.2 0.44 9.6 0.2 3.0 3 1 1 4 4 4 0 FAD binding domain Arg_decarbox_C PF17944.1 ORZ03913.1 - 0.18 12.4 0.4 4.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Sel1 PF08238.12 ORZ03914.1 - 1.8e-45 152.4 20.3 4.4e-08 33.5 0.1 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 ORZ03914.1 - 0.015 15.9 7.9 0.44 11.3 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat F-box PF00646.33 ORZ03915.1 - 1.2e-06 28.3 1.9 2.1e-06 27.5 0.6 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORZ03915.1 - 2.8e-06 27.1 4.5 8e-06 25.6 1.5 3.0 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 ORZ03915.1 - 0.5 10.9 14.8 6.7 7.3 3.4 5.7 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORZ03916.1 - 1.5e-07 31.1 0.0 4.5e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ03916.1 - 9.2e-06 25.4 0.1 3.9e-05 23.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ORZ03916.1 - 0.0056 17.1 4.4 4.5 7.8 0.0 5.3 4 3 3 7 7 7 1 Leucine Rich repeats (2 copies) F-box PF00646.33 ORZ03917.1 - 8.9e-06 25.5 0.4 1.9e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORZ03917.1 - 2.8e-05 23.9 1.6 6e-05 22.9 0.3 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORZ03918.1 - 0.023 15.1 5.8 10 6.7 1.1 3.7 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORZ03918.1 - 3 8.7 6.4 10 7.1 0.4 3.6 3 1 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.7 ORZ03919.1 - 3.3e-06 26.9 0.2 8.9e-06 25.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ03919.1 - 0.0019 18.0 0.1 0.0048 16.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain UPF0061 PF02696.14 ORZ03920.1 - 5e-87 292.6 0.0 2.3e-54 184.9 0.0 2.9 1 1 1 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family DUF202 PF02656.15 ORZ03921.1 - 3.1e-11 43.5 0.2 1.5e-10 41.3 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF2976 PF11190.8 ORZ03921.1 - 0.21 11.4 4.8 0.3 10.9 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) YtpI PF14007.6 ORZ03921.1 - 0.31 11.2 4.9 4.9 7.4 0.1 2.7 3 0 0 3 3 3 0 YtpI-like protein zf-HIT PF04438.16 ORZ03922.1 - 2.1e-07 30.7 11.4 3.2e-07 30.1 11.4 1.3 1 0 0 1 1 1 1 HIT zinc finger Herpes_UL74 PF07982.12 ORZ03922.1 - 0.06 12.3 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpes UL74 glycoproteins PolC_DP2 PF03833.13 ORZ03922.1 - 0.31 8.9 4.5 0.41 8.5 4.5 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Peptidase_C74 PF12387.8 ORZ03922.1 - 0.97 8.9 4.8 1.5 8.2 4.8 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Astro_capsid_p PF12226.8 ORZ03922.1 - 2.8 7.0 10.7 5 6.2 10.7 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Hydrolase_4 PF12146.8 ORZ03923.1 - 7.9e-59 198.8 0.0 9.1e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORZ03923.1 - 1.4e-13 51.1 1.7 1.4e-10 41.3 0.9 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORZ03923.1 - 9.5e-13 49.3 0.0 1.2e-12 48.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORZ03923.1 - 6.6e-05 22.8 0.0 0.059 13.2 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORZ03923.1 - 0.00028 20.4 0.3 0.049 13.1 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 ORZ03923.1 - 0.012 15.3 0.0 0.042 13.5 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 ORZ03923.1 - 0.017 14.7 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF1749 PF08538.10 ORZ03923.1 - 0.034 13.2 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Thioesterase PF00975.20 ORZ03923.1 - 0.035 14.2 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2920 PF11144.8 ORZ03923.1 - 0.059 12.5 0.1 3.8 6.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2920) DUF3089 PF11288.8 ORZ03923.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) FUSC PF04632.12 ORZ03924.1 - 0.2 10.2 2.9 0.43 9.0 2.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cu_amine_oxid PF01179.20 ORZ03925.1 - 2.4e-153 510.9 0.0 3e-153 510.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORZ03925.1 - 1.6e-20 73.4 0.1 4.4e-20 72.0 0.1 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ORZ03925.1 - 5.1e-09 36.3 0.3 1.3e-08 35.0 0.1 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 ORZ03926.1 - 4.9e-153 509.9 0.0 6e-153 509.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORZ03926.1 - 2.6e-18 66.3 0.0 6.7e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ORZ03926.1 - 8.1e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain SRP-alpha_N PF04086.13 ORZ03928.1 - 0.035 14.0 25.5 0.049 13.5 25.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MEA1 PF06910.11 ORZ03929.1 - 2e-13 51.1 8.2 3.1e-13 50.5 8.2 1.4 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Sec7 PF01369.20 ORZ03930.1 - 5.4e-36 124.0 0.1 8.5e-36 123.3 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORZ03930.1 - 3.7e-14 53.1 0.0 7.7e-13 48.9 0.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORZ03930.1 - 3.1e-08 34.1 0.0 2.7e-06 27.8 0.0 2.9 1 1 0 1 1 1 1 PH domain PH_6 PF15406.6 ORZ03930.1 - 0.019 15.2 0.0 0.075 13.3 0.0 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain p450 PF00067.22 ORZ03931.1 - 1.3e-30 106.5 0.0 1.6e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cytochrom_C_2 PF01322.20 ORZ03931.1 - 0.069 14.1 0.0 0.23 12.4 0.0 1.7 1 1 1 2 2 2 0 Cytochrome C' p450 PF00067.22 ORZ03932.1 - 8.3e-92 308.3 0.0 9.3e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LPD26 PF18842.1 ORZ03932.1 - 0.011 15.7 0.1 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 Cytochrom_C_2 PF01322.20 ORZ03932.1 - 0.17 12.8 0.0 0.55 11.1 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C' Presenilin PF01080.17 ORZ03933.1 - 0.58 8.9 11.7 1.7 7.3 3.7 2.0 2 0 0 2 2 2 0 Presenilin Zn_Tnp_IS1 PF03811.13 ORZ03933.1 - 0.77 9.5 3.0 0.49 10.2 0.2 2.2 2 0 0 2 2 2 0 InsA N-terminal domain RNA_pol_Rpc4 PF05132.14 ORZ03933.1 - 7.9 6.9 13.4 2.3 8.6 2.5 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 p450 PF00067.22 ORZ03934.1 - 4.8e-92 309.1 0.0 5.8e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LPD26 PF18842.1 ORZ03934.1 - 0.025 14.5 0.1 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 eIF-5_eIF-2B PF01873.17 ORZ03935.1 - 6.5e-43 145.3 0.2 1.3e-42 144.4 0.2 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ORZ03935.1 - 0.0031 17.0 0.3 0.0067 15.9 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding SART-1 PF03343.13 ORZ03935.1 - 0.039 12.5 18.9 0.05 12.2 18.9 1.2 1 0 0 1 1 1 0 SART-1 family Lar_restr_allev PF14354.6 ORZ03935.1 - 0.07 13.5 0.5 0.28 11.6 0.5 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF2752 PF10825.8 ORZ03935.1 - 0.22 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Arc_trans_TRASH PF08394.10 ORZ03935.1 - 2.3 8.6 6.7 6 7.3 0.1 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain Cytochrom_c3_2 PF14537.6 ORZ03935.1 - 6.6 7.3 5.9 0.63 10.5 0.2 2.3 3 1 0 3 3 3 0 Cytochrome c3 Pkinase PF00069.25 ORZ03936.1 - 4.9e-69 232.6 0.0 7.6e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORZ03936.1 - 5.7e-49 166.7 0.0 9.7e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 ORZ03936.1 - 3.4e-27 94.7 0.1 6.3e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 ORZ03936.1 - 9.1e-12 44.9 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORZ03936.1 - 1.2e-10 41.6 0.0 2.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 ORZ03936.1 - 3.5e-07 30.8 0.0 7.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 ORZ03936.1 - 5.1e-07 29.3 0.0 2.6e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like SAM_4 PF18017.1 ORZ03936.1 - 0.0021 18.0 0.1 0.0042 17.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 ORZ03936.1 - 0.006 15.4 2.3 0.019 13.7 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Spindle_Spc25 PF08234.12 ORZ03936.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 PKD PF00801.20 ORZ03936.1 - 0.21 11.4 0.9 0.55 10.1 0.1 2.0 2 0 0 2 2 2 0 PKD domain DSPc PF00782.20 ORZ03937.1 - 6.9e-27 93.9 0.0 1.4e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORZ03937.1 - 8.9e-05 22.2 1.5 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 ORZ03937.1 - 0.00019 21.7 0.0 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 ORZ03937.1 - 0.021 15.0 0.1 0.076 13.1 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Pex14_N PF04695.13 ORZ03937.1 - 0.73 10.5 8.5 0.32 11.6 1.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HABP4_PAI-RBP1 PF04774.15 ORZ03938.1 - 7.8e-08 33.2 11.0 7.8e-08 33.2 11.0 3.6 1 1 2 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 ORZ03938.1 - 1.5e-06 28.9 9.8 1.5e-06 28.9 9.8 4.2 2 1 0 2 2 2 1 Stm1 peroxidase PF00141.23 ORZ03939.1 - 3.7e-46 157.7 0.0 5.2e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Nas2_N PF18265.1 ORZ03940.1 - 1.4e-29 101.8 0.4 2.1e-29 101.2 0.4 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 ORZ03940.1 - 5.4e-07 29.9 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 ORZ03940.1 - 9.3e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 ORZ03940.1 - 2.6e-05 24.5 0.0 4.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ORZ03940.1 - 4.6e-05 23.2 0.2 0.00011 21.9 0.2 1.7 1 0 0 1 1 1 1 PDZ domain Ribophorin_II PF05817.14 ORZ03941.1 - 2.9e-34 118.7 2.2 3.2e-34 118.5 2.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_C2 PF00648.21 ORZ03942.1 - 8.1e-44 149.8 0.0 1.7e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 ORZ03942.1 - 2.2e-19 70.1 1.8 2.8e-05 24.4 0.2 5.4 4 1 0 4 4 4 3 Calpain large subunit, domain III MIT PF04212.18 ORZ03942.1 - 1.2e-08 34.9 8.4 0.00022 21.2 2.6 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Wzt_C PF14524.6 ORZ03942.1 - 0.067 13.2 0.1 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 Wzt C-terminal domain 4_1_CTD PF05902.13 ORZ03942.1 - 0.15 12.2 2.1 0.43 10.7 2.1 1.7 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) GCV_H PF01597.19 ORZ03943.1 - 8e-44 148.5 1.4 9.5e-44 148.2 1.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 ORZ03943.1 - 0.00059 19.8 0.6 0.00089 19.2 0.6 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 ORZ03943.1 - 0.00097 18.9 0.2 0.0025 17.6 0.3 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme HILPDA PF15220.6 ORZ03943.1 - 0.04 14.0 0.0 5.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated FUSC PF04632.12 ORZ03944.1 - 4.1 5.8 7.8 1 7.8 4.4 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family IQ PF00612.27 ORZ03947.1 - 4.3e-06 26.1 1.2 1.2e-05 24.7 1.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif ERM PF00769.19 ORZ03947.1 - 0.0057 16.5 11.1 0.012 15.5 11.1 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Lzipper-MIP1 PF14389.6 ORZ03947.1 - 0.14 12.5 14.4 0.33 11.3 1.1 3.2 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4407 PF14362.6 ORZ03947.1 - 0.24 10.7 7.9 0.36 10.1 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNaseH_like PF04308.12 ORZ03947.1 - 0.86 9.5 4.6 2 8.3 0.5 2.4 1 1 1 2 2 2 0 Ribonuclease H-like DUF2383 PF09537.10 ORZ03947.1 - 1.2 9.5 8.3 3.6 8.0 4.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF2383) LMBR1 PF04791.16 ORZ03947.1 - 5.2 5.8 4.6 8.2 5.2 4.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SPT16 PF08644.11 ORZ03947.1 - 6.7 6.9 8.0 21 5.3 6.9 2.2 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) V_ATPase_I PF01496.19 ORZ03947.1 - 8.4 4.2 8.2 12 3.6 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HR1 PF02185.16 ORZ03947.1 - 9.9 6.4 18.2 39 4.5 0.5 3.4 1 1 1 2 2 2 0 Hr1 repeat Glyco_hydro_18 PF00704.28 ORZ03948.1 - 2.1e-69 234.7 4.4 2.4e-69 234.5 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cwf_Cwc_15 PF04889.12 ORZ03949.1 - 0.012 15.4 12.6 0.014 15.2 12.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 ORZ03949.1 - 0.25 10.7 16.2 0.3 10.4 16.2 1.1 1 0 0 1 1 1 0 BUD22 ALMT PF11744.8 ORZ03949.1 - 1.6 7.5 3.9 1.8 7.3 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Galactosyl_T PF01762.21 ORZ03950.1 - 1.6e-19 70.5 0.0 2.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 ORZ03950.1 - 1e-15 58.1 14.5 1e-15 58.1 14.5 2.3 1 1 1 2 2 2 1 N-glycosylation protein Gly_transf_sug PF04488.15 ORZ03950.1 - 1.5e-08 35.1 0.2 3.8e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 ORZ03950.1 - 9.9e-07 29.0 0.4 2.6e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region Caps_synth PF05704.12 ORZ03950.1 - 0.0018 17.7 0.5 0.0042 16.5 0.5 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORZ03950.1 - 0.027 13.8 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Paired_CXXCH_1 PF09699.10 ORZ03950.1 - 5.5 6.8 9.3 5.7 6.8 3.6 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) SWI-SNF_Ssr4 PF08549.10 ORZ03951.1 - 7.7e-11 41.4 5.1 7.7e-11 41.4 5.1 2.3 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1750) Q_salvage PF10343.9 ORZ03951.1 - 0.064 12.8 0.5 0.093 12.3 0.5 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family GED PF02212.18 ORZ03951.1 - 2.4 8.4 5.7 6.6 7.0 2.1 2.3 1 1 1 2 2 2 0 Dynamin GTPase effector domain Proteasome PF00227.26 ORZ03952.1 - 3.6e-47 160.3 0.0 5.2e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORZ03952.1 - 2.2e-13 49.6 0.1 3.5e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LRR_6 PF13516.6 ORZ03953.1 - 0.002 18.0 2.9 5.1 7.4 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat Zn-ribbon_8 PF09723.10 ORZ03953.1 - 0.019 15.1 0.5 0.058 13.5 0.5 1.8 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 ORZ03953.1 - 0.21 11.6 2.0 0.3 11.1 0.3 2.1 2 0 0 2 2 2 0 Double zinc ribbon DSHCT PF08148.12 ORZ03954.1 - 1.1e-51 174.8 0.1 2.5e-51 173.6 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 ORZ03954.1 - 4.7e-37 126.8 0.0 9.5e-37 125.8 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 ORZ03954.1 - 2.3e-27 96.6 0.4 3.9e-27 95.9 0.4 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 ORZ03954.1 - 5.1e-17 62.2 0.0 1.1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORZ03954.1 - 1.3e-06 28.7 0.0 8.2e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORZ03954.1 - 4.9e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_3rep PF18868.1 ORZ03954.1 - 0.78 10.4 2.7 0.7 10.6 0.1 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats N1221 PF07923.13 ORZ03955.1 - 3.8e-07 29.6 0.1 5.2e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 N1221-like protein CcdA PF07362.12 ORZ03955.1 - 0.72 10.3 2.8 7.4 7.1 0.2 2.4 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF3402 PF11882.8 ORZ03956.1 - 2.3e-51 175.3 8.8 2.9e-32 112.4 0.9 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF3402) p450 PF00067.22 ORZ03957.1 - 2.1e-68 231.1 0.0 2.6e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1912 PF08930.10 ORZ03957.1 - 0.23 11.6 1.8 0.85 9.8 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) PPTA PF01239.22 ORZ03958.1 - 5e-42 140.4 23.1 6.1e-11 41.7 0.3 6.3 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DPBB_1 PF03330.18 ORZ03959.1 - 2.5e-09 37.3 0.6 6.5e-09 35.9 0.6 1.6 1 1 0 1 1 1 1 Lytic transglycolase 60KD_IMP PF02096.20 ORZ03960.1 - 1.2e-28 100.1 0.6 1.7e-28 99.6 0.6 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Glyco_hydro_35 PF01301.19 ORZ03961.1 - 2.1e-88 297.0 4.0 3.2e-88 296.4 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ORZ03961.1 - 3.5e-50 169.3 6.1 6.5e-31 107.2 0.1 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ORZ03961.1 - 1.2e-38 132.7 0.3 2.2e-38 131.9 0.3 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ORZ03961.1 - 3.8e-21 74.4 0.5 1.2e-20 72.8 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 ORZ03961.1 - 1.1e-08 34.8 0.3 3.6e-06 26.6 0.2 2.9 1 1 1 2 2 2 1 Beta-galactosidase DHHA2 PF02833.14 ORZ03962.1 - 1e-28 100.3 0.0 2.5e-28 99.0 0.0 1.6 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 ORZ03962.1 - 3.9e-07 30.3 0.0 9.1e-07 29.1 0.0 1.6 1 1 1 2 2 2 1 DHH family Ribosomal_60s PF00428.19 ORZ03963.1 - 2.8e-27 95.1 12.0 3.3e-27 94.9 12.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 ORZ03963.1 - 0.053 13.9 0.0 0.088 13.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Prog_receptor PF02161.15 ORZ03963.1 - 0.11 11.2 3.2 0.13 10.9 3.2 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF3854 PF12965.7 ORZ03963.1 - 0.18 11.8 0.7 0.26 11.3 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF4611 PF15387.6 ORZ03963.1 - 0.28 11.4 4.1 0.71 10.1 3.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) DUF3824 PF12868.7 ORZ03963.1 - 1.3 9.7 3.1 1.6 9.4 3.1 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Carn_acyltransf PF00755.20 ORZ03964.1 - 3.8e-186 620.2 0.0 4.6e-186 619.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Cyclin PF08613.11 ORZ03965.1 - 3.1e-38 131.7 0.7 3.1e-38 131.7 0.7 2.7 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORZ03965.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sec10 PF07393.11 ORZ03966.1 - 5e-116 388.8 0.0 6.9e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 ORZ03966.1 - 8.9e-08 31.9 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORZ03966.1 - 3.3e-05 23.7 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain RINT1_TIP1 PF04437.13 ORZ03966.1 - 0.03 13.2 0.2 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 RINT-1 / TIP-1 family LPD11 PF18824.1 ORZ03966.1 - 0.077 13.1 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 Terminase_3C PF17288.2 ORZ03966.1 - 0.16 12.4 1.3 7 7.0 0.1 2.6 2 0 0 2 2 2 0 Terminase RNAseH like domain Mito_carr PF00153.27 ORZ03967.1 - 4.3e-28 97.1 6.6 2e-12 46.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORZ03967.1 - 0.052 12.7 1.0 0.16 11.1 0.1 2.2 2 1 0 2 2 2 0 Gammaproteobacterial serine protease DUF4326 PF14216.6 ORZ03967.1 - 0.11 13.2 0.0 0.64 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) Rap_GAP PF02145.15 ORZ03968.1 - 8.8e-42 142.8 0.2 2.1e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Rap/ran-GAP Statherin PF03875.13 ORZ03968.1 - 0.92 9.7 3.8 1.6 8.9 2.2 2.3 2 0 0 2 2 2 0 Statherin Caskin1-CID PF16600.5 ORZ03968.1 - 9 7.0 6.8 6.5 7.4 3.8 2.4 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Ribosomal_L2_C PF03947.18 ORZ03969.1 - 2.5e-54 182.8 3.2 2.5e-54 182.8 3.2 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORZ03969.1 - 4.1e-25 87.5 0.1 7.7e-25 86.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3471 PF11954.8 ORZ03970.1 - 0.093 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Mucin PF01456.17 ORZ03970.1 - 0.39 10.7 15.5 0.59 10.1 15.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 ORZ03970.1 - 1.7 6.5 6.3 2 6.3 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mg_trans_NIPA PF05653.14 ORZ03971.1 - 1.7e-26 93.1 15.0 4.8e-14 52.2 1.5 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORZ03971.1 - 0.00014 22.0 4.6 0.00014 22.0 4.6 3.4 2 1 1 4 4 4 2 EamA-like transporter family Ac76 PF05814.11 ORZ03971.1 - 0.16 12.0 1.2 0.56 10.3 1.2 1.9 1 0 0 1 1 1 0 Orf76 (Ac76) DUF4131 PF13567.6 ORZ03971.1 - 7.6 6.2 11.0 8.9 5.9 3.0 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) Cwf_Cwc_15 PF04889.12 ORZ03972.1 - 0.1 12.3 16.8 0.19 11.4 16.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 ORZ03972.1 - 0.69 10.6 12.0 1.8 9.3 12.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BUD22 PF09073.10 ORZ03972.1 - 1 8.7 10.8 1.7 7.9 10.8 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORZ03972.1 - 1.1 8.6 7.9 1.5 8.1 7.9 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 ORZ03972.1 - 5.8 6.4 10.9 11 5.6 10.9 1.4 1 0 0 1 1 1 0 PPP4R2 DnaJ PF00226.31 ORZ03973.1 - 9.3e-13 48.1 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain GHL10 PF02638.15 ORZ03973.1 - 0.049 12.7 0.1 0.063 12.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 RRM_1 PF00076.22 ORZ03974.1 - 1.5e-83 274.6 3.1 8.8e-21 73.5 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORZ03974.1 - 5.9e-29 100.0 1.7 2.3e-28 98.2 1.4 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORZ03974.1 - 4.8e-11 42.3 0.0 0.08 12.5 0.0 3.8 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORZ03974.1 - 4.5e-06 26.7 0.1 1.3 9.1 0.0 5.0 4 1 0 4 4 4 1 RNA recognition motif OB_RNB PF08206.11 ORZ03974.1 - 0.0026 17.4 3.7 2.4 7.9 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 ORZ03974.1 - 0.0049 16.8 0.8 25 5.0 0.1 4.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.8 ORZ03974.1 - 0.0088 16.1 0.0 5.5 7.2 0.0 3.3 3 0 0 3 3 3 1 Cobalamin biosynthesis central region DUF4523 PF15023.6 ORZ03974.1 - 0.029 14.2 0.0 50 3.7 0.0 3.8 1 1 0 4 4 4 0 Protein of unknown function (DUF4523) Asp PF00026.23 ORZ03975.1 - 1.2e-89 300.8 10.8 1.5e-89 300.5 10.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORZ03975.1 - 1.7e-15 57.7 9.4 1.7e-10 41.4 0.6 2.9 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORZ03975.1 - 0.00033 21.3 1.6 0.017 15.7 0.1 2.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 ORZ03975.1 - 0.0083 15.9 0.1 0.38 10.5 0.0 2.9 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal Asp PF00026.23 ORZ03976.1 - 4.7e-88 295.6 5.9 5.6e-88 295.4 5.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORZ03976.1 - 3.4e-15 56.7 2.3 6e-09 36.4 0.2 3.0 3 0 0 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORZ03976.1 - 0.0018 18.9 0.8 0.14 12.8 0.1 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 ORZ03976.1 - 0.073 12.8 0.1 0.55 10.0 0.0 2.3 2 1 1 3 3 3 0 Xylanase inhibitor C-terminal ALMT PF11744.8 ORZ03977.1 - 0.039 12.8 7.6 0.063 12.1 7.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4239 PF14023.6 ORZ03977.1 - 0.91 9.2 7.7 0.59 9.8 3.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) DUF1664 PF07889.12 ORZ03977.1 - 5.1 7.2 7.6 0.43 10.6 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Glyco_hydro_16 PF00722.21 ORZ03978.1 - 6.3e-23 81.1 0.1 8.6e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DDE_Tnp_IS1595 PF12762.7 ORZ03981.1 - 0.0022 18.0 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_32 PF13565.6 ORZ03983.1 - 2.8e-05 24.6 0.1 4.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain TerB_C PF15615.6 ORZ03983.1 - 0.041 14.2 0.1 0.049 13.9 0.1 1.2 1 0 0 1 1 1 0 TerB-C domain DUF1748 PF08520.10 ORZ03985.1 - 2.2e-25 88.3 0.0 2.4e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) FlxA PF14282.6 ORZ03987.1 - 0.0035 17.3 1.4 0.0051 16.8 1.4 1.2 1 0 0 1 1 1 1 FlxA-like protein CHIP_TPR_N PF18391.1 ORZ03987.1 - 0.059 14.2 2.0 0.092 13.5 2.0 1.3 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain M20_dimer PF07687.14 ORZ03988.1 - 8.7e-14 51.4 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ORZ03988.1 - 1.1e-08 35.0 0.1 1.8e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DisA-linker PF10635.9 ORZ03988.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Cation_efflux PF01545.21 ORZ03989.1 - 3.2e-54 183.7 13.1 4.8e-54 183.1 13.1 1.3 1 0 0 1 1 1 1 Cation efflux family PhaG_MnhG_YufB PF03334.14 ORZ03989.1 - 9.2 6.6 8.4 2.7 8.3 1.6 2.7 2 1 0 2 2 2 0 Na+/H+ antiporter subunit Metallophos PF00149.28 ORZ03991.1 - 3.2e-33 116.0 0.2 4.1e-33 115.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORZ03991.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pex14_N PF04695.13 ORZ03992.1 - 2.3e-26 93.3 0.6 2.3e-26 93.3 0.6 2.2 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PNK3P PF08645.11 ORZ03995.1 - 3.2e-55 186.2 0.0 5.9e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 ORZ03995.1 - 3.7e-18 66.1 0.4 1.4e-15 57.7 0.4 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORZ03995.1 - 1.1e-07 31.6 2.5 0.00011 21.8 1.0 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Hydrolase_6 PF13344.6 ORZ03995.1 - 0.00024 21.1 0.0 0.0099 16.0 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 ORZ03995.1 - 0.00026 20.3 0.0 0.0061 15.9 0.0 2.4 2 1 1 3 3 3 2 Zeta toxin Ribosomal_S17_N PF16205.5 ORZ03995.1 - 0.022 15.1 0.1 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Ribosomal_S17 N-terminal HAD PF12710.7 ORZ03995.1 - 0.029 14.8 0.2 0.54 10.6 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MMR_HSR1 PF01926.23 ORZ03995.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ParBc_2 PF08857.11 ORZ03995.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Putative ParB-like nuclease HAD_2 PF13419.6 ORZ03995.1 - 0.07 13.2 0.1 14 5.7 0.0 2.9 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Protoglobin PF11563.8 ORZ03996.1 - 7.4e-43 146.2 0.2 8.8e-43 145.9 0.2 1.1 1 0 0 1 1 1 1 Protoglobin Arginosuc_synth PF00764.19 ORZ03996.1 - 0.13 11.5 0.2 14 4.8 0.0 2.1 2 0 0 2 2 2 0 Arginosuccinate synthase PhoLip_ATPase_C PF16212.5 ORZ03997.1 - 2.2e-84 283.1 25.9 2.2e-84 283.1 25.9 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORZ03997.1 - 3.7e-25 87.4 2.0 1.5e-24 85.4 2.0 2.2 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORZ03997.1 - 1.4e-12 48.4 0.7 2.2e-07 31.4 0.1 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORZ03997.1 - 8.8e-12 45.0 0.0 4.7e-11 42.6 0.0 2.2 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORZ03997.1 - 6.3e-09 35.6 0.0 1.7e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORZ03997.1 - 0.00063 19.6 0.1 0.0051 16.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMG_box PF00505.19 ORZ03998.1 - 5.5e-12 45.9 4.5 1.9e-11 44.2 4.5 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORZ03998.1 - 1.2e-08 35.4 3.0 1.2e-08 35.4 3.0 2.8 3 0 0 3 3 3 1 HMG-box domain DUF4087 PF13316.6 ORZ04000.1 - 0.24 11.9 0.9 0.35 11.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) zf-C2H2 PF00096.26 ORZ04001.1 - 3.7e-17 61.7 18.6 4.7e-06 26.8 1.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORZ04001.1 - 8.8e-15 54.4 16.8 1e-07 32.1 0.8 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORZ04001.1 - 1.3e-13 50.5 17.3 0.00025 21.6 1.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORZ04001.1 - 6.4e-13 48.4 15.9 2.1e-05 24.4 0.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORZ04001.1 - 1.4e-08 34.8 8.4 0.011 16.1 0.3 3.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORZ04001.1 - 2.5e-08 34.2 11.0 0.00028 21.3 0.6 3.0 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 ORZ04001.1 - 1.3e-06 28.5 11.5 0.028 14.8 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORZ04001.1 - 7.5e-05 22.8 6.8 0.037 14.2 3.4 3.0 2 1 1 3 3 3 2 Zinc ribbon domain zf_ZIC PF18366.1 ORZ04001.1 - 0.0002 21.4 3.6 0.5 10.5 0.1 3.1 2 1 1 3 3 3 1 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 ORZ04001.1 - 0.0032 18.1 7.1 0.69 10.6 0.1 2.6 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zinc-ribbons_6 PF07191.12 ORZ04001.1 - 0.0047 16.9 4.7 0.28 11.2 1.8 2.5 1 1 1 2 2 2 1 zinc-ribbons Spt46 PF17734.1 ORZ04001.1 - 0.0047 16.8 5.2 0.4 10.4 1.5 2.3 1 1 1 2 2 2 2 Spermatogenesis-associated protein 46 zf_UBZ PF18439.1 ORZ04001.1 - 0.0085 15.7 5.9 0.9 9.2 0.2 3.2 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 ORZ04001.1 - 0.013 15.6 13.8 0.73 10.0 0.5 3.2 1 1 2 3 3 3 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 ORZ04001.1 - 0.016 15.5 9.9 2.3 8.6 10.4 3.0 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TFIIS_C PF01096.18 ORZ04001.1 - 0.03 14.2 5.1 2.2 8.2 0.1 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) DZR PF12773.7 ORZ04001.1 - 0.049 13.7 7.2 0.24 11.5 3.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon C1_4 PF07975.12 ORZ04001.1 - 0.06 13.6 10.2 0.93 9.8 9.8 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_8 PF15909.5 ORZ04001.1 - 0.1 12.9 6.4 0.067 13.5 3.6 1.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-trcl PF13451.6 ORZ04001.1 - 0.11 12.5 7.1 19 5.3 0.1 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 ORZ04001.1 - 0.12 12.2 10.8 6 6.7 0.3 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORZ04001.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Sprouty PF05210.13 ORZ04001.1 - 0.15 12.5 4.1 0.32 11.4 4.1 1.6 1 1 0 1 1 1 0 Sprouty protein (Spry) zf-C2H2_9 PF16293.5 ORZ04001.1 - 0.17 11.7 2.4 17 5.3 0.0 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) PHD PF00628.29 ORZ04001.1 - 0.21 11.5 5.9 17 5.4 0.0 2.9 2 1 1 3 3 3 0 PHD-finger zinc_ribbon_15 PF17032.5 ORZ04001.1 - 0.21 12.3 5.4 2.5 8.9 5.4 2.0 1 1 0 1 1 1 0 zinc-ribbon family zf-LYAR PF08790.11 ORZ04001.1 - 0.22 11.5 8.9 0.29 11.1 0.4 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn_Tnp_IS1595 PF12760.7 ORZ04001.1 - 0.22 11.5 6.3 0.094 12.7 1.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.11 ORZ04001.1 - 0.24 11.2 6.8 1.2 9.0 0.3 2.9 1 1 2 3 3 3 0 GAGA factor zf-nanos PF05741.13 ORZ04001.1 - 0.26 11.5 7.5 13 6.1 0.3 3.1 3 0 0 3 3 3 0 Nanos RNA binding domain zf_C2H2_ZHX PF18387.1 ORZ04001.1 - 0.26 10.9 15.1 4.3 7.1 0.1 3.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_ribbon_SprT PF17283.2 ORZ04001.1 - 0.4 10.6 8.9 0.4 10.6 2.7 2.4 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 ORZ04001.1 - 0.46 10.4 6.4 7.2 6.6 0.4 3.0 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 ORZ04001.1 - 0.56 10.3 5.1 5.4 7.1 5.1 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C4 PF00105.18 ORZ04001.1 - 0.98 9.9 8.1 2.1 8.9 2.8 2.6 1 1 1 2 2 2 0 Zinc finger, C4 type (two domains) zf-MYST PF17772.1 ORZ04001.1 - 1.7 8.3 5.6 9.4 5.9 0.1 2.8 2 1 1 3 3 3 0 MYST family zinc finger domain zf-BED PF02892.15 ORZ04001.1 - 3 8.0 10.0 25 5.0 1.2 2.9 1 1 1 2 2 2 0 BED zinc finger Rubredoxin_2 PF18073.1 ORZ04001.1 - 4.7 7.0 9.0 17 5.3 0.3 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-HC5HC2H_2 PF13832.6 ORZ04002.1 - 2.8e-13 50.0 14.6 4e-13 49.5 8.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 ORZ04002.1 - 1.1e-11 44.1 1.9 1.1e-11 44.1 1.9 2.6 2 1 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 ORZ04002.1 - 7.4e-11 42.2 5.1 7.4e-11 42.2 5.1 3.0 1 1 2 3 3 3 1 PHD-like zinc-binding domain PHD PF00628.29 ORZ04002.1 - 8.6e-07 28.8 5.5 8.6e-07 28.8 5.5 2.9 3 0 0 3 3 2 2 PHD-finger Nop14 PF04147.12 ORZ04002.1 - 0.02 13.1 17.3 0.032 12.5 17.3 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 ORZ04002.1 - 0.045 13.1 21.8 0.068 12.5 21.8 1.2 1 0 0 1 1 1 0 BUD22 Slu7 PF11708.8 ORZ04002.1 - 0.088 12.5 14.1 0.2 11.4 14.1 1.5 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Astro_capsid_p PF12226.8 ORZ04002.1 - 0.21 10.7 15.5 0.39 9.8 15.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SDA1 PF05285.12 ORZ04002.1 - 0.42 10.0 23.1 0.67 9.3 23.1 1.2 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 ORZ04002.1 - 0.49 10.1 7.5 1.2 8.8 7.5 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FANCL_C PF11793.8 ORZ04002.1 - 0.88 9.8 18.2 0.049 13.8 3.0 3.0 2 1 1 3 3 3 0 FANCL C-terminal domain CDC45 PF02724.14 ORZ04002.1 - 1 7.6 18.6 1.5 7.1 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1631 PF07793.11 ORZ04002.1 - 1.3 7.3 14.9 0.15 10.5 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Vfa1 PF08432.10 ORZ04002.1 - 1.5 9.1 16.6 0.04 14.2 8.5 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.12 ORZ04002.1 - 2 6.9 25.1 3 6.3 25.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 ORZ04002.1 - 3.3 5.7 25.7 5.5 5.0 25.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 ORZ04002.1 - 5.7 7.1 29.2 1.1 9.4 24.3 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 ORZ04002.1 - 5.8 7.7 25.4 1.4 9.7 20.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4820 PF16091.5 ORZ04002.1 - 6.6 6.0 13.4 16 4.7 13.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Paf1 PF03985.13 ORZ04002.1 - 8.1 5.3 22.5 16 4.3 22.5 1.4 1 0 0 1 1 1 0 Paf1 CDO_I PF05995.12 ORZ04005.1 - 3.7e-32 111.0 0.2 6.8e-32 110.1 0.2 1.4 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 ORZ04005.1 - 7.1e-05 22.4 0.0 9.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO AMMECR1 PF01871.17 ORZ04006.1 - 6.2e-45 152.8 0.0 7.3e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DUF1681 PF07933.14 ORZ04007.1 - 1.5e-50 170.7 0.0 1.7e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CotH PF08757.11 ORZ04008.1 - 1.1e-27 97.4 5.8 1.7e-27 96.8 5.8 1.2 1 0 0 1 1 1 1 CotH kinase protein TypeIII_RM_meth PF12564.8 ORZ04008.1 - 0.13 12.3 1.9 2.5 8.3 0.2 3.0 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit zf-LITAF-like PF10601.9 ORZ04009.1 - 0.0002 21.6 0.4 0.00023 21.4 0.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain CIDR1_gamma PF18562.1 ORZ04011.1 - 0.25 11.5 0.1 2.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Cysteine-Rich Interdomain Region 1 gamma DUF1325 PF07039.11 ORZ04012.1 - 7.8e-38 129.6 0.1 1.4e-37 128.8 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 ORZ04012.1 - 0.00082 19.2 0.0 0.0025 17.6 0.0 1.9 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 ORZ04012.1 - 0.0016 18.2 0.0 0.057 13.2 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain SRP68 PF16969.5 ORZ04012.1 - 0.026 13.5 1.2 0.029 13.4 0.4 1.4 1 1 0 1 1 1 0 RNA-binding signal recognition particle 68 DUF4537 PF15057.6 ORZ04012.1 - 0.051 13.6 0.0 14 5.7 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4537) IHABP4_N PF16174.5 ORZ04012.1 - 0.058 14.0 3.9 0.096 13.3 3.9 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal CNOT1_TTP_bind PF16417.5 ORZ04012.1 - 0.063 12.5 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain TUDOR PF00567.24 ORZ04012.1 - 0.13 12.3 0.0 2.9 8.0 0.0 2.6 3 0 0 3 3 3 0 Tudor domain Glyco_hydro_17 PF00332.18 ORZ04013.1 - 7.6e-13 48.7 5.6 9.4e-11 41.9 1.0 3.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Helo_like_N PF17111.5 ORZ04013.1 - 0.0074 15.7 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Wzt_C PF14524.6 ORZ04014.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Wzt C-terminal domain EB_dh PF09459.10 ORZ04014.1 - 0.076 13.0 0.0 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase Lactamase_B_2 PF12706.7 ORZ04015.1 - 5.1e-22 78.4 0.0 1.7e-20 73.4 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORZ04015.1 - 2.5e-06 27.5 0.0 0.0026 17.7 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain HMGL-like PF00682.19 ORZ04016.1 - 4.3e-96 321.5 0.2 5.6e-96 321.1 0.2 1.1 1 0 0 1 1 1 1 HMGL-like Suv3_N PF18114.1 ORZ04016.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Ribosomal_S8e PF01201.22 ORZ04017.1 - 3.9e-54 182.5 0.3 4.6e-54 182.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e RhoGAP PF00620.27 ORZ04018.1 - 3.7e-08 33.3 0.0 7.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 ORZ04018.1 - 2.2e-05 24.1 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CENP-R PF06729.12 ORZ04019.1 - 0.077 12.9 0.0 0.088 12.7 0.0 1.0 1 0 0 1 1 1 0 Kinetochore component, CENP-R GRP PF07172.11 ORZ04020.1 - 0.00038 21.1 0.8 0.00058 20.5 0.8 1.3 1 0 0 1 1 1 1 Glycine rich protein family Defensin_propep PF00879.18 ORZ04020.1 - 0.14 12.5 0.2 0.19 12.0 0.2 1.2 1 0 0 1 1 1 0 Defensin propeptide VPS13_mid_rpt PF16910.5 ORZ04021.1 - 6.6e-83 277.7 10.2 5.6e-78 261.6 0.1 5.3 5 0 0 5 5 5 3 Repeating coiled region of VPS13 SHR-BD PF06650.12 ORZ04021.1 - 7.8e-80 268.1 1.6 6.2e-79 265.2 0.2 2.8 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 ORZ04021.1 - 4.9e-74 249.1 7.6 7.6e-73 245.2 0.3 4.2 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 ORZ04021.1 - 8.9e-70 234.1 2.3 1.4e-63 213.9 0.0 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 ORZ04021.1 - 8.3e-40 135.5 0.3 2.2e-39 134.1 0.3 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORZ04021.1 - 3.3e-09 37.0 0.0 9.3e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain XPG_I PF00867.18 ORZ04027.1 - 0.00029 21.1 0.0 0.00087 19.6 0.0 1.9 1 0 0 1 1 1 1 XPG I-region OrfB_Zn_ribbon PF07282.11 ORZ04027.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2058 PF09831.9 ORZ04027.1 - 0.15 12.2 0.1 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) XPG_I PF00867.18 ORZ04028.1 - 0.00024 21.4 0.0 0.00077 19.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region DUF2058 PF09831.9 ORZ04028.1 - 0.13 12.4 0.2 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Mg_trans_NIPA PF05653.14 ORZ04029.1 - 7.7e-25 87.6 8.1 4.4e-14 52.3 1.6 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORZ04029.1 - 0.00011 22.4 2.3 0.00011 22.4 2.3 2.6 3 0 0 3 3 3 2 EamA-like transporter family DUF3394 PF11874.8 ORZ04029.1 - 0.06 13.0 0.4 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) FAM176 PF14851.6 ORZ04029.1 - 0.11 12.1 0.7 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 FAM176 family Herpes_LMP1 PF05297.11 ORZ04029.1 - 3.2 6.9 14.1 0.011 15.0 3.2 1.9 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1418 PF07214.12 ORZ04029.1 - 4.4 7.2 5.3 5.2 7.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Syncephalastrum_racemosum_NRRL_2496-Synrac1/GCA_002105135.1_Synrac1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Syncephalastrum_racemosum_NRRL_2496-Synrac1/GCA_002105135.1_Synrac1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Syncephalastrum_racemosum_NRRL_2496-Synrac1/GCA_002105135.1_Synrac1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Syncephalastrum_racemosum_NRRL_2496-Synrac1/GCA_002105135.1_Synrac1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 06:37:37 2019 # [ok]