# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Neisseria_TspB PF05616.13 EIM78923.1 - 1.5 7.2 13.9 1.6 7.1 13.9 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Chromo PF00385.24 EIM78924.1 - 5.4e-06 26.2 0.4 7e-06 25.9 0.4 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain XPG_I_2 PF12813.7 EIM78928.1 - 0.058 12.8 0.0 0.066 12.7 0.0 1.0 1 0 0 1 1 1 0 XPG domain containing Retrotrans_gag PF03732.17 EIM78933.1 - 4.6e-15 55.7 0.1 1.5e-14 54.0 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIM78933.1 - 1.1e-05 25.3 9.7 0.004 17.2 2.3 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.6 EIM78933.1 - 0.0054 16.6 2.7 0.013 15.4 2.7 1.6 1 0 0 1 1 1 1 Nudix N-terminal NPV_P10 PF05531.12 EIM78933.1 - 0.036 14.5 3.4 0.15 12.6 1.0 2.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DHHA1 PF02272.19 EIM78933.1 - 0.058 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 DHHA1 domain SO_alpha_A3 PF17806.1 EIM78933.1 - 0.31 11.4 2.5 0.53 10.6 0.4 2.2 2 0 0 2 2 2 0 Sarcosine oxidase A3 domain DUF948 PF06103.11 EIM78933.1 - 0.66 10.3 5.1 0.91 9.8 2.6 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MIP-T3_C PF17749.1 EIM78933.1 - 1 9.3 2.9 0.72 9.8 0.9 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region zf-CCHC_5 PF14787.6 EIM78933.1 - 3.5 7.4 6.3 11 5.9 0.2 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RNase_H PF00075.24 EIM78934.1 - 8.2e-05 22.8 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 RNase H Prok-TraM PF09228.10 EIM78936.1 - 0.65 10.4 4.4 2 8.8 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Paf1 PF03985.13 EIM78937.1 - 0.13 11.2 2.6 0.17 10.8 2.6 1.1 1 0 0 1 1 1 0 Paf1 Cnd2 PF05786.14 EIM78937.1 - 0.16 10.6 5.2 0.22 10.2 5.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 BUD22 PF09073.10 EIM78937.1 - 0.24 10.7 7.4 0.34 10.2 7.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EIM78937.1 - 0.59 8.3 2.9 0.78 8.0 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EIM78937.1 - 0.64 8.2 6.2 0.81 7.8 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.11 EIM78937.1 - 6.6 5.4 6.0 9.6 4.8 6.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus gag-asp_proteas PF13975.6 EIM78938.1 - 0.00012 22.6 0.0 0.00014 22.3 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIM78938.1 - 0.00043 20.9 0.0 0.00047 20.8 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EIM78938.1 - 0.04 13.7 0.0 0.04 13.7 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EIM78939.1 - 7.1e-15 55.1 0.3 3.1e-14 53.0 0.1 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIM78939.1 - 7.1e-06 25.9 9.7 0.0031 17.5 2.3 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.6 EIM78939.1 - 0.0042 17.0 2.7 0.01 15.7 2.7 1.6 1 0 0 1 1 1 1 Nudix N-terminal zf-CCHC_5 PF14787.6 EIM78939.1 - 2.1 8.1 6.3 8.4 6.2 0.2 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CHCH PF06747.13 EIM78941.1 - 0.17 12.1 0.3 0.24 11.6 0.3 1.2 1 0 0 1 1 1 0 CHCH domain DUF4554 PF15091.6 EIM78950.1 - 0.11 11.4 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CxC6 PF18721.1 EIM78951.1 - 4e-24 84.7 3.6 4.7e-24 84.5 3.6 1.1 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases THF_DHG_CYH_C PF02882.19 EIM78953.1 - 3.5e-15 55.7 0.0 4.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DivIC PF04977.15 EIM78957.1 - 0.05 13.4 0.9 0.11 12.3 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator Cnn_1N PF07989.11 EIM78957.1 - 0.056 13.6 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF220 PF02713.14 EIM78958.1 - 0.16 12.1 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF220 DUF2396 PF09654.10 EIM78958.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) PH_9 PF15410.6 EIM78959.1 - 0.16 12.4 1.2 0.42 11.0 1.2 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Patatin PF01734.22 EIM78961.1 - 4.4e-26 92.3 0.0 7.4e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2373 PF10180.9 EIM78964.1 - 0.034 14.0 0.0 0.093 12.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) PBP PF01161.20 EIM78965.1 - 2.8e-12 47.1 0.0 3.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 EIM78966.1 - 2.3e-09 37.7 0.0 2.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Retrotrans_gag PF03732.17 EIM78967.1 - 1.5e-14 54.0 0.3 6.8e-14 51.9 0.1 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein Nudix_N_2 PF14803.6 EIM78967.1 - 0.021 14.8 4.2 0.055 13.4 4.2 1.7 1 0 0 1 1 1 0 Nudix N-terminal zf-CCHC PF00098.23 EIM78967.1 - 0.079 13.1 0.9 0.079 13.1 0.9 2.3 2 0 0 2 2 2 0 Zinc knuckle Zn-ribbon_8 PF09723.10 EIM78967.1 - 0.15 12.2 0.9 0.27 11.4 0.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Ribonuc_red_sm PF00268.21 EIM78968.1 - 1.6e-05 24.5 0.1 4.2e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain DFP PF04127.15 EIM78968.1 - 0.16 11.8 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein SAT PF16073.5 EIM78974.1 - 1.3e-09 38.1 0.0 2.4e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis SIR2 PF02146.17 EIM78975.1 - 3.6e-30 105.2 0.0 1.8e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 Sir2 family RVT_1 PF00078.27 EIM78977.1 - 9.6e-09 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EIM78977.1 - 0.15 12.8 0.0 0.37 11.5 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Kelch_3 PF13415.6 EIM78978.1 - 0.92 9.9 3.8 6 7.3 1.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain NFACT-R_1 PF05670.13 EIM78979.1 - 5e-41 139.8 0.0 8.2e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain Tnp_P_element_C PF12596.8 EIM78979.1 - 0.083 13.4 0.8 0.16 12.6 0.8 1.4 1 0 0 1 1 1 0 87kDa Transposase zf-CCHC PF00098.23 EIM78980.1 - 0.0071 16.4 2.8 0.014 15.5 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIM78980.1 - 0.22 11.4 5.6 0.059 13.2 1.9 2.0 2 0 0 2 2 2 0 Zinc knuckle HNH_repeat PF18780.1 EIM78980.1 - 0.44 10.4 0.1 0.44 10.4 0.1 2.8 3 0 0 3 3 3 0 Homing endonuclease repeat Anti-TRAP PF15777.5 EIM78981.1 - 0.025 14.6 0.3 0.07 13.1 0.3 1.8 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EIM78981.1 - 0.028 14.4 0.5 0.028 14.4 0.5 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE_2 PF02318.16 EIM78981.1 - 0.077 13.2 0.2 0.077 13.2 0.2 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 EIM78981.1 - 0.11 12.5 13.4 0.46 10.5 3.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 EIM78981.1 - 0.77 10.3 9.4 1.2 9.6 8.6 1.8 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 EIM78981.1 - 3.5 7.7 13.0 8.2 6.5 11.4 2.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 EIM78981.1 - 5 7.2 12.1 3.7 7.6 1.8 2.7 2 1 0 2 2 2 0 zinc-ribbons Keratin PF02422.16 EIM78982.1 - 0.17 11.6 0.3 0.43 10.3 0.3 1.6 1 0 0 1 1 1 0 Keratin SOTI PF17079.5 EIM78983.1 - 0.088 13.2 5.1 2.6 8.5 0.8 3.3 2 0 0 2 2 2 0 Male-specific protein scotti AAA_22 PF13401.6 EIM78984.1 - 0.00021 21.6 0.0 0.42 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain CIDE-N PF02017.15 EIM78987.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 CIDE-N domain Retrotran_gag_2 PF14223.6 EIM78988.1 - 1.5e-18 66.8 0.4 1.8e-18 66.5 0.4 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.22 EIM78988.1 - 0.07 12.8 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Retrotrans_gag PF03732.17 EIM78989.1 - 7.2e-08 32.6 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 EIM78989.1 - 5.3e-07 29.5 0.0 1.1e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) BTB PF00651.31 EIM78991.1 - 0.00083 19.6 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain HpaB PF03241.13 EIM78992.1 - 0.0079 15.3 0.0 3.3 6.7 0.0 2.4 1 1 1 2 2 2 2 4-hydroxyphenylacetate 3-hydroxylase C terminal NRho PF16733.5 EIM78992.1 - 0.0093 16.0 0.1 45 4.2 0.0 4.3 5 0 0 5 5 5 0 Rhomboid N-terminal domain PH_BEACH PF14844.6 EIM78992.1 - 0.027 14.6 0.0 15 5.8 0.0 3.4 4 0 0 4 4 4 0 PH domain associated with Beige/BEACH C6_DPF PF10170.9 EIM78992.1 - 0.034 14.5 9.7 17 5.9 0.7 5.1 4 2 1 5 5 5 0 Cysteine-rich domain Sprouty PF05210.13 EIM78992.1 - 0.11 12.9 26.8 0.2 12.1 2.8 3.3 3 1 0 3 3 3 0 Sprouty protein (Spry) Ldh_1_C PF02866.18 EIM78994.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain MULE PF10551.9 EIM78997.1 - 3.7e-07 30.5 0.0 3e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 MULE transposase domain Retrotrans_gag PF03732.17 EIM78999.1 - 1.7e-14 53.9 0.3 8e-14 51.7 0.1 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIM78999.1 - 7.1e-06 25.9 9.7 0.0031 17.5 2.3 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.6 EIM78999.1 - 0.0042 17.0 2.7 0.01 15.7 2.7 1.6 1 0 0 1 1 1 1 Nudix N-terminal zf-CCHC_5 PF14787.6 EIM78999.1 - 2.1 8.1 6.3 8.4 6.2 0.2 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Pkinase PF00069.25 EIM79000.1 - 1.8e-06 27.5 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EIM79000.1 - 1.6e-05 24.4 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIM79000.1 - 1.8e-05 24.4 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM79000.1 - 2e-05 24.7 0.0 0.00014 21.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EIM79000.1 - 0.00013 21.4 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM79000.1 - 0.00053 18.9 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EIM79000.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EIM79000.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EIM79000.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WaaY PF06176.11 EIM79000.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DDE_Tnp_4 PF13359.6 EIM79004.1 - 3.7e-22 78.7 0.0 4.7e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.6 EIM79005.1 - 0.12 12.7 0.6 0.2 12.1 0.1 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain dsrm PF00035.26 EIM79006.1 - 2.6e-08 34.4 0.2 4.7e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EIM79006.1 - 2e-05 24.7 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIM79006.1 - 0.046 14.3 0.0 0.19 12.4 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease III domain Mito_fiss_reg PF05308.11 EIM79006.1 - 0.33 11.0 8.3 0.5 10.4 8.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Retrotrans_gag PF03732.17 EIM79007.1 - 1.9e-08 34.4 0.0 3.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 EIM79007.1 - 4.4e-07 29.8 0.0 9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 EIM79008.1 - 1.3e-05 25.7 0.0 1.3e-05 25.7 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EIM79008.1 - 0.00024 20.9 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EIM79008.1 - 0.0012 19.3 0.0 0.0012 19.3 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2E PF12382.8 EIM79008.1 - 0.087 12.8 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon peptidase CDC45 PF02724.14 EIM79009.1 - 1.9 6.7 3.3 2.5 6.3 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Dimer_Tnp_hAT PF05699.14 EIM79011.1 - 2.9e-06 27.0 0.2 0.0066 16.2 0.0 3.0 2 1 1 3 3 3 2 hAT family C-terminal dimerisation region PSS PF03034.15 EIM79021.1 - 0.39 10.4 6.2 0.58 9.9 6.2 1.2 1 0 0 1 1 1 0 Phosphatidyl serine synthase MULE PF10551.9 EIM79023.1 - 8.7e-11 42.1 0.0 4.5e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EIM79023.1 - 3.4e-05 23.4 0.0 6.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger DUF4218 PF13960.6 EIM79024.1 - 6.4e-06 25.8 0.0 2.2e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 EIM79025.1 - 0.0068 15.7 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 RR_TM4-6 PF06459.12 EIM79028.1 - 0.4 10.5 6.5 0.66 9.8 6.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EIM79028.1 - 0.69 10.3 4.3 1.6 9.2 4.3 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPL5 PF18168.1 EIM79028.1 - 8.7 5.5 7.8 12 5.1 7.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Connexin PF00029.19 EIM79028.1 - 9.2 6.0 6.1 17 5.1 6.1 1.3 1 0 0 1 1 1 0 Connexin DUF4611 PF15387.6 EIM79029.1 - 0.022 15.0 4.0 0.072 13.3 4.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 EIM79029.1 - 3.5 5.8 6.2 0.27 9.5 1.4 1.5 2 0 0 2 2 2 0 CDC45-like protein CCDC-167 PF15188.6 EIM79030.1 - 0.17 12.2 0.9 0.59 10.5 0.9 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Syntaxin PF00804.25 EIM79030.1 - 0.21 11.2 3.1 0.46 10.1 3.1 1.5 1 0 0 1 1 1 0 Syntaxin EzrA PF06160.12 EIM79032.1 - 0.00075 17.8 8.6 0.001 17.4 8.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FPP PF05911.11 EIM79032.1 - 0.001 17.4 12.9 0.0014 16.9 12.9 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil KASH_CCD PF14662.6 EIM79032.1 - 0.0045 16.8 13.0 0.0091 15.8 13.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 EIM79032.1 - 0.0088 14.2 10.6 0.014 13.6 10.6 1.2 1 0 0 1 1 1 1 HOOK protein YabA PF06156.13 EIM79032.1 - 0.039 14.6 7.0 0.99 10.1 1.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CdvA PF18822.1 EIM79032.1 - 0.18 11.7 8.9 0.15 11.9 3.4 2.6 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Leu_zip PF15294.6 EIM79032.1 - 0.22 11.0 9.0 0.33 10.4 9.0 1.2 1 0 0 1 1 1 0 Leucine zipper HeLo PF14479.6 EIM79032.1 - 0.28 11.0 12.6 1.3 8.8 10.4 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation ING PF12998.7 EIM79032.1 - 0.58 10.8 3.6 0.64 10.6 2.1 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4200 PF13863.6 EIM79032.1 - 1.6 9.2 13.2 3.8 7.9 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4472 PF14739.6 EIM79032.1 - 2 9.2 10.2 0.94 10.2 2.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) BLOC1_2 PF10046.9 EIM79032.1 - 2.6 8.4 7.1 11 6.4 3.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1465 PF07323.12 EIM79032.1 - 3.3 7.6 13.7 0.44 10.4 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DNA_repr_REX1B PF14966.6 EIM79032.1 - 3.5 8.3 7.7 1.7 9.4 1.7 2.3 1 1 1 2 2 2 0 DNA repair REX1-B DUF1664 PF07889.12 EIM79032.1 - 3.9 7.5 5.2 25 4.9 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EIM79032.1 - 5.4 6.2 7.2 3.5 6.8 5.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 EIM79032.1 - 5.8 6.1 18.6 0.41 9.9 4.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EIM79032.1 - 6.4 6.9 6.9 13 6.0 6.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 EIM79032.1 - 8.3 6.7 13.0 2.1 8.6 4.5 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein TPR_MLP1_2 PF07926.12 EIM79032.1 - 8.4 6.5 21.3 12 5.9 3.1 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 EIM79032.1 - 9.8 6.5 6.2 9.5 6.5 3.7 2.2 1 1 1 2 2 2 0 Haemolysin XhlA BSP_II PF05432.11 EIM79033.1 - 0.02 14.6 3.6 0.04 13.6 3.6 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 EIM79033.1 - 0.086 11.1 0.8 0.16 10.3 0.8 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EIM79033.1 - 0.45 9.8 10.2 0.86 8.9 10.2 1.4 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EIM79033.1 - 3.8 6.9 8.1 7.7 5.8 8.1 1.4 1 0 0 1 1 1 0 SDA1 Dimer_Tnp_hAT PF05699.14 EIM79034.1 - 6.4e-13 48.3 0.1 6.8e-13 48.2 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PBP PF01161.20 EIM79036.1 - 8.4e-12 45.5 0.0 8.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GGDEF_2 PF17853.1 EIM79036.1 - 0.047 14.0 0.0 0.095 13.0 0.0 1.5 1 1 0 1 1 1 0 GGDEF-like domain CAP_N PF01213.19 EIM79037.1 - 0.052 13.0 6.5 0.11 12.0 6.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EIM79037.1 - 1.8 8.6 10.9 0.26 11.3 4.9 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator SOTI PF17079.5 EIM79039.1 - 0.79 10.2 9.5 1.9 8.9 0.5 3.4 2 1 1 3 3 3 0 Male-specific protein scotti AAA_22 PF13401.6 EIM79040.1 - 0.17 12.1 0.2 0.31 11.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EIM79040.1 - 0.24 10.3 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 EIM79040.1 - 0.27 11.1 0.0 0.42 10.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Helicase_C PF00271.31 EIM79041.1 - 3e-10 40.4 0.0 5.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EIM79041.1 - 0.0025 17.1 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 EIM79041.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SMC_N PF02463.19 EIM79045.1 - 0.046 13.1 0.1 0.099 12.1 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain XH PF03469.14 EIM79045.1 - 0.19 11.6 3.6 1.1 9.2 0.7 2.1 1 1 1 2 2 2 0 XH domain DUF724 PF05266.14 EIM79045.1 - 0.66 9.8 7.9 1 9.2 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cauli_VI PF01693.16 EIM79046.1 - 5.2e-14 52.3 3.8 5.1e-06 26.7 0.7 3.8 4 0 0 4 4 4 2 Caulimovirus viroplasmin PRIMA1 PF16101.5 EIM79046.1 - 9.3 6.3 14.0 0.32 11.1 3.4 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PADR1 PF08063.12 EIM79049.1 - 0.018 14.8 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain BATS PF06968.13 EIM79049.1 - 0.17 12.1 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain GRA6 PF05084.13 EIM79053.1 - 0.071 13.1 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DDE_3 PF13358.6 EIM79054.1 - 2.9e-08 33.6 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease tify PF06200.14 EIM79054.1 - 0.061 12.7 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 tify domain DivIC PF04977.15 EIM79056.1 - 0.014 15.2 1.9 0.024 14.4 1.9 1.3 1 0 0 1 1 1 0 Septum formation initiator Rootletin PF15035.6 EIM79056.1 - 0.052 13.6 0.5 0.098 12.7 0.3 1.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 EIM79056.1 - 0.053 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA LdpA_C PF12617.8 EIM79056.1 - 0.15 11.7 0.5 0.52 9.9 0.3 1.8 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal EPO_TPO PF00758.18 EIM79056.1 - 0.18 11.8 0.3 3.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin Transposase_21 PF02992.14 EIM79058.1 - 0.0096 15.2 0.5 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 EIM79059.1 - 1.2e-05 24.9 0.4 9.6e-05 22.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4218) zf-CCHC PF00098.23 EIM79061.1 - 7.1e-08 32.2 3.0 1.5e-07 31.2 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 EIM79061.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EIM79061.1 - 0.015 15.9 0.0 0.045 14.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EIM79061.1 - 0.032 14.8 0.0 0.082 13.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 EIM79061.1 - 0.04 13.9 0.3 0.17 11.8 0.3 2.1 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EIM79061.1 - 0.063 13.0 6.7 0.13 12.0 6.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EIM79061.1 - 0.076 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2B PF12384.8 EIM79061.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase zf-CCHC_2 PF13696.6 EIM79061.1 - 0.39 10.6 3.2 0.73 9.7 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Prominin PF05478.11 EIM79062.1 - 4 5.3 6.3 7.8 4.3 6.3 1.3 1 0 0 1 1 1 0 Prominin V-SNARE_C PF12352.8 EIM79065.1 - 0.053 13.8 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus HNH_repeat PF18780.1 EIM79070.1 - 0.0037 17.0 2.5 2.5 8.0 0.1 3.1 3 0 0 3 3 3 2 Homing endonuclease repeat DEAD PF00270.29 EIM79071.1 - 2.7e-06 27.3 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CT47 PF15623.6 EIM79071.1 - 0.27 11.0 3.4 0.51 10.1 3.4 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 KDZ PF18758.1 EIM79073.1 - 6.8e-47 159.9 0.0 1.1e-46 159.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM79073.1 - 1.3e-34 118.6 0.1 1.3e-34 118.6 0.1 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM79073.1 - 4.4e-07 30.0 0.1 1.3e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EIM79073.1 - 0.0013 18.6 0.1 0.0013 18.6 0.1 2.2 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases DUF573 PF04504.14 EIM79073.1 - 0.049 14.3 0.2 2.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF573 PIF1 PF05970.14 EIM79077.1 - 3.6e-05 23.1 0.0 0.00035 19.8 0.0 2.4 1 1 0 1 1 1 1 PIF1-like helicase Mononeg_mRNAcap PF14318.6 EIM79077.1 - 0.11 11.7 0.3 0.19 10.9 0.3 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V PIF1 PF05970.14 EIM79078.1 - 1.9e-13 50.3 0.0 2.3e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EIM79078.1 - 5.2e-13 49.1 0.0 6.9e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM79078.1 - 4.3e-09 36.9 0.0 7.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EIM79078.1 - 0.00094 19.2 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 EIM79078.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain MeaB PF03308.16 EIM79078.1 - 0.0018 17.3 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EIM79078.1 - 0.004 17.0 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DEAD PF00270.29 EIM79078.1 - 0.0067 16.2 0.3 2.3 8.0 0.0 2.1 1 1 0 2 2 2 2 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 EIM79078.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EIM79078.1 - 0.015 14.5 0.1 0.074 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 EIM79078.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EIM79078.1 - 0.019 15.4 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EIM79078.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 EIM79078.1 - 0.04 13.4 0.2 0.083 12.4 0.1 1.7 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EIM79078.1 - 0.059 13.6 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EIM79078.1 - 0.093 12.8 0.0 0.32 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EIM79078.1 - 0.13 12.3 0.1 0.32 11.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 EIM79078.1 - 0.17 11.3 0.1 0.43 10.0 0.1 1.7 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain FPN1 PF06963.12 EIM79079.1 - 0.31 9.6 0.3 0.42 9.1 0.3 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Helitron_like_N PF14214.6 EIM79080.1 - 8.1e-22 78.4 0.0 1e-21 78.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PPP4R2 PF09184.11 EIM79083.1 - 0.064 12.8 5.9 0.11 12.0 5.9 1.3 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 EIM79083.1 - 0.28 11.1 13.1 0.44 10.5 13.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 EIM79083.1 - 4.7 5.2 14.6 7 4.6 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PGA2 PF07543.12 EIM79084.1 - 0.01 15.8 4.1 0.012 15.6 4.1 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Radial_spoke PF04712.12 EIM79084.1 - 0.12 11.3 6.5 0.12 11.3 6.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein TRAP_alpha PF03896.16 EIM79084.1 - 0.31 10.2 2.7 0.34 10.1 2.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.19 EIM79084.1 - 0.82 10.3 11.4 1.2 9.8 11.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein SDA1 PF05285.12 EIM79084.1 - 0.94 8.8 10.1 1 8.7 10.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIM79084.1 - 0.94 7.6 9.5 0.94 7.6 9.5 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EIM79084.1 - 1.2 7.6 3.0 1.3 7.5 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EIM79084.1 - 3.2 5.9 7.0 3.2 5.9 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EIM79084.1 - 5.8 6.1 8.0 7.5 5.8 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EIM79084.1 - 6.8 4.7 10.4 6.6 4.7 10.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi PAC1 PF16094.5 EIM79084.1 - 7.4 5.7 6.9 9.5 5.3 6.9 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Ku PF02735.16 EIM79085.1 - 8.1 6.1 8.5 18 5.0 1.3 2.3 2 0 0 2 2 2 0 Ku70/Ku80 beta-barrel domain Spo0M PF07070.11 EIM79086.1 - 0.017 14.7 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 SpoOM protein DUF4140 PF13600.6 EIM79087.1 - 0.0046 17.4 0.5 0.013 16.0 0.5 1.8 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 EIM79087.1 - 0.0056 16.7 2.9 0.012 15.7 2.9 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 EIM79087.1 - 0.0078 16.4 0.8 0.017 15.3 0.8 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.13 EIM79087.1 - 0.14 12.2 0.3 0.28 11.3 0.3 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SHE3 PF17078.5 EIM79087.1 - 0.32 10.7 0.7 0.53 10.0 0.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 PKcGMP_CC PF16808.5 EIM79087.1 - 0.94 9.4 8.1 0.089 12.7 1.0 2.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 EIM79087.1 - 1.6 8.1 4.0 2.5 7.3 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CxC5 PF18718.1 EIM79088.1 - 1.3e-33 115.5 1.1 1.3e-33 115.5 1.1 2.3 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EIM79088.1 - 9.4e-24 83.5 5.9 9.4e-24 83.5 5.9 2.2 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases DUF702 PF05142.12 EIM79090.1 - 0.0025 18.3 0.1 0.0058 17.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF702) AbfB PF05270.13 EIM79090.1 - 0.016 15.2 0.0 0.65 10.0 0.1 2.3 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B (ABFB) domain FdhE PF04216.12 EIM79091.1 - 0.46 10.3 1.9 26 4.6 0.5 2.5 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation SDA1 PF05285.12 EIM79091.1 - 2.5 7.5 15.4 4.7 6.5 15.4 1.4 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 EIM79095.1 - 1.2 8.9 9.7 2.6 7.8 9.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RRN3 PF05327.11 EIM79095.1 - 1.9 6.9 5.2 3.1 6.2 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EIM79095.1 - 2.1 6.4 18.8 3.3 5.7 18.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EIM79095.1 - 9.4 5.6 16.4 20 4.5 16.4 1.5 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.7 EIM79097.1 - 0.0075 16.1 0.1 0.058 13.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM79097.1 - 0.15 12.0 3.8 2.1 8.3 0.1 3.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EIM79098.1 - 0.036 14.0 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 F-box-like Helitron_like_N PF14214.6 EIM79100.1 - 2.7e-21 76.7 0.0 3e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDOST_48kD PF03345.14 EIM79102.1 - 0.096 11.5 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta PIF1 PF05970.14 EIM79103.1 - 8e-05 22.0 0.1 0.0065 15.7 0.1 2.7 2 1 0 2 2 2 2 PIF1-like helicase CDK2AP PF09806.9 EIM79103.1 - 0.019 15.0 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein AAA_11 PF13086.6 EIM79103.1 - 0.087 12.6 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Helitron_like_N PF14214.6 EIM79104.1 - 0.034 14.4 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus KduI PF04962.12 EIM79104.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family F-box PF00646.33 EIM79110.1 - 0.00014 21.7 0.1 0.00032 20.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM79110.1 - 0.00037 20.3 0.4 0.00065 19.5 0.4 1.4 1 0 0 1 1 1 1 F-box-like Viral_Beta_CD PF04530.12 EIM79111.1 - 0.071 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family UPF0014 PF03649.13 EIM79111.1 - 0.24 10.7 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) Tropomyosin PF00261.20 EIM79112.1 - 0.22 10.9 0.2 0.32 10.3 0.2 1.1 1 0 0 1 1 1 0 Tropomyosin dsrm PF00035.26 EIM79113.1 - 0.0051 17.5 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif HEAT PF02985.22 EIM79117.1 - 4.3e-06 26.5 0.2 0.011 15.9 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EIM79117.1 - 0.00067 20.2 0.0 0.68 10.6 0.0 2.7 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EIM79117.1 - 0.025 15.1 0.5 2.9 8.5 0.1 3.1 2 1 1 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 EIM79117.1 - 0.15 12.5 0.0 0.59 10.6 0.0 2.0 2 1 0 2 2 2 0 HEAT repeats Importin_rep_4 PF18808.1 EIM79118.1 - 0.019 15.3 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Importin repeat Utp12 PF04003.12 EIM79118.1 - 0.032 14.5 0.2 0.054 13.8 0.2 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family MMS19_C PF12460.8 EIM79118.1 - 2 7.5 3.7 2.9 6.9 3.7 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal SAB PF04382.13 EIM79121.1 - 0.11 12.6 1.5 4.9 7.3 0.2 3.0 2 0 0 2 2 2 0 SAB domain p450 PF00067.22 EIM79122.1 - 3.9e-72 243.5 0.0 1.3e-71 241.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM79123.1 - 1.4e-46 159.3 0.0 1.6e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EIM79125.1 - 2.8e-38 131.8 45.4 2.8e-38 131.8 45.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM79125.1 - 4.1e-18 65.1 21.4 1.6e-17 63.2 21.4 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIM79125.1 - 8.9e-16 57.8 9.4 8.9e-16 57.8 9.4 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Terpene_synth_C PF03936.16 EIM79126.1 - 0.00068 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DNA_ligase_OB_2 PF14743.6 EIM79127.1 - 2e-21 75.8 0.1 4e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 EIM79127.1 - 3.6e-10 39.8 0.0 5.6e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain adh_short PF00106.25 EIM79131.1 - 2.6e-25 89.0 0.0 1.9e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79131.1 - 2.5e-16 60.0 0.0 1.8e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79131.1 - 9.1e-08 32.2 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM79131.1 - 0.00028 20.5 0.1 0.0007 19.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EIM79131.1 - 0.034 14.4 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EIM79131.1 - 0.056 12.8 0.1 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EIM79131.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Piwi PF02171.17 EIM79132.1 - 8.8e-17 61.3 0.0 1.3e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EIM79132.1 - 5.4e-09 35.6 0.1 3.1e-08 33.2 0.0 2.3 3 0 0 3 3 3 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EIM79132.1 - 1.6e-05 25.2 0.0 5.2e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EIM79132.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute Fasciclin PF02469.22 EIM79135.1 - 0.067 13.4 0.2 1.2 9.3 0.0 2.2 1 1 0 2 2 2 0 Fasciclin domain Pkinase PF00069.25 EIM79136.1 - 0.021 14.2 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Filament PF00038.21 EIM79138.1 - 0.0021 17.7 3.6 0.003 17.2 3.6 1.3 1 0 0 1 1 1 1 Intermediate filament protein Bacillus_HBL PF05791.11 EIM79138.1 - 0.003 17.4 1.0 0.0037 17.1 1.0 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 EIM79138.1 - 0.0034 17.7 1.5 0.0059 16.9 1.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) BshC PF10079.9 EIM79138.1 - 0.0036 16.1 1.9 0.0043 15.8 1.9 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC CdvA PF18822.1 EIM79138.1 - 0.013 15.3 2.5 0.57 10.0 0.2 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain AAA_13 PF13166.6 EIM79138.1 - 0.013 14.2 0.4 0.016 13.9 0.4 1.2 1 0 0 1 1 1 0 AAA domain Lzipper-MIP1 PF14389.6 EIM79138.1 - 0.014 15.7 2.3 0.024 14.9 2.1 1.6 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 SHE3 PF17078.5 EIM79138.1 - 0.015 15.0 2.3 0.02 14.6 2.3 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Baculo_PEP_C PF04513.12 EIM79138.1 - 0.017 15.2 1.6 0.043 13.9 1.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 EIM79138.1 - 0.017 15.5 2.9 0.02 15.3 2.0 1.7 1 1 0 1 1 1 0 Snapin/Pallidin DUF2397 PF09660.10 EIM79138.1 - 0.018 13.9 3.5 0.021 13.7 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) HMMR_N PF15905.5 EIM79138.1 - 0.02 14.4 5.3 0.027 14.0 5.3 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Leu_zip PF15294.6 EIM79138.1 - 0.021 14.4 6.3 0.027 14.0 6.3 1.1 1 0 0 1 1 1 0 Leucine zipper DUF4239 PF14023.6 EIM79138.1 - 0.028 14.1 1.3 0.035 13.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Syntaxin_2 PF14523.6 EIM79138.1 - 0.03 14.7 2.1 0.054 13.9 0.6 1.9 2 0 0 2 2 2 0 Syntaxin-like protein Exonuc_VII_L PF02601.15 EIM79138.1 - 0.039 13.5 3.8 0.04 13.5 3.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 EIM79138.1 - 0.041 14.2 3.7 0.068 13.4 2.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein ZapB PF06005.12 EIM79138.1 - 0.045 14.2 3.7 0.66 10.5 3.4 2.6 1 1 0 1 1 1 0 Cell division protein ZapB DUF155 PF02582.14 EIM79138.1 - 0.047 13.8 0.9 0.39 10.8 0.2 2.0 1 1 1 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Nsp1_C PF05064.13 EIM79138.1 - 0.055 13.3 1.7 0.11 12.3 1.6 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF2383 PF09537.10 EIM79138.1 - 0.056 13.8 1.6 0.1 13.0 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2383) Spc7 PF08317.11 EIM79138.1 - 0.062 12.2 6.6 0.089 11.7 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 EIM79138.1 - 0.072 11.0 0.9 0.086 10.8 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPPI_inhib PF14895.6 EIM79138.1 - 0.075 12.2 0.2 0.094 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor Muted PF14942.6 EIM79138.1 - 0.085 13.2 4.4 0.13 12.7 4.4 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.11 EIM79138.1 - 0.086 13.1 1.4 2.7 8.3 0.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 EIM79138.1 - 0.087 12.1 2.5 0.11 11.8 2.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 EIM79138.1 - 0.096 12.7 2.3 0.24 11.4 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 EIM79138.1 - 0.11 12.7 4.3 0.18 11.9 4.3 1.4 1 0 0 1 1 1 0 Tropomyosin like Phage_HK97_TLTM PF06120.11 EIM79138.1 - 0.11 11.7 1.1 0.14 11.3 1.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Fzo_mitofusin PF04799.13 EIM79138.1 - 0.12 11.9 6.6 2.3 7.8 0.4 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF16 PF01519.16 EIM79138.1 - 0.17 12.4 0.9 1.1 9.8 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4298 PF14131.6 EIM79138.1 - 0.19 11.7 1.3 1.4 8.9 1.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) Nup54 PF13874.6 EIM79138.1 - 0.23 11.6 3.8 0.43 10.7 3.8 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.11 EIM79138.1 - 0.23 11.9 1.5 2.7 8.5 0.4 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 EIM79138.1 - 0.24 11.8 5.1 3.4 8.1 2.2 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EMP24_GP25L PF01105.24 EIM79138.1 - 0.32 10.9 2.2 0.7 9.8 0.6 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD HalX PF08663.10 EIM79138.1 - 0.55 10.6 5.5 0.97 9.8 1.5 2.7 1 1 1 2 2 2 0 HalX domain LPP PF04728.13 EIM79138.1 - 0.98 9.9 4.0 22 5.5 2.7 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Spc24 PF08286.11 EIM79138.1 - 1.5 9.1 6.2 1.6 9.0 2.7 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DEAD PF00270.29 EIM79139.1 - 0.00019 21.3 0.0 0.0011 18.7 0.0 2.2 2 2 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM79140.1 - 0.0081 16.5 0.0 0.038 14.3 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain WcbI PF18588.1 EIM79140.1 - 0.04 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI Rrn6 PF10214.9 EIM79140.1 - 0.17 10.4 16.3 0.12 10.9 15.1 1.3 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SRP-alpha_N PF04086.13 EIM79140.1 - 1.4 8.8 18.2 2.3 8.1 18.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TMEM214 PF10151.9 EIM79140.1 - 1.5 7.2 7.0 2.2 6.6 7.0 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MMU163 PF17119.5 EIM79140.1 - 9.9 5.2 11.1 2.4 7.3 6.4 1.9 1 1 1 2 2 2 0 Mitochondrial protein up-regulated during meiosis Cauli_VI PF01693.16 EIM79141.1 - 0.00072 19.8 0.3 0.0014 18.9 0.3 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin SLX9 PF15341.6 EIM79142.1 - 0.056 13.8 2.4 0.11 12.8 0.5 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Hydrolase_4 PF12146.8 EIM79146.1 - 1.7e-15 56.9 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM79146.1 - 0.00048 20.8 0.1 0.00056 20.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EIM79146.1 - 0.053 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-MYND PF01753.18 EIM79148.1 - 2.1e-05 24.5 16.0 2.1e-05 24.5 16.0 2.1 2 0 0 2 2 2 1 MYND finger Roughex PF06020.11 EIM79148.1 - 4.5 6.3 8.8 9.8 5.2 8.8 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 EIM79148.1 - 8.8 4.4 12.3 16 3.5 12.3 1.3 1 0 0 1 1 1 0 Nop14-like family KilA-N PF04383.13 EIM79150.1 - 0.0019 18.0 0.2 0.023 14.5 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain dsrm PF00035.26 EIM79151.1 - 2.6e-08 34.4 0.2 4.7e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EIM79151.1 - 2e-05 24.7 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIM79151.1 - 0.046 14.3 0.0 0.19 12.4 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease III domain Mito_fiss_reg PF05308.11 EIM79151.1 - 0.33 11.0 8.3 0.5 10.4 8.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Helicase_C PF00271.31 EIM79153.1 - 0.00034 20.9 0.0 0.00052 20.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EIM79154.1 - 7.2e-33 113.8 0.4 9.1e-33 113.4 0.4 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.8 EIM79154.1 - 5.8e-12 45.4 0.1 8.8e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 KRAB PF01352.27 EIM79154.1 - 0.011 15.4 0.4 0.032 13.9 0.2 1.9 2 0 0 2 2 2 0 KRAB box Ribosomal_S7 PF00177.21 EIM79157.1 - 7.3e-37 126.3 1.5 9e-37 126.0 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Amidohydro_1 PF01979.20 EIM79158.1 - 1.2e-14 54.4 0.0 1.1e-13 51.2 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM79158.1 - 3.5e-11 43.3 11.6 1.5e-07 31.3 0.1 3.6 3 1 1 4 4 4 3 Amidohydrolase family Cluap1 PF10234.9 EIM79159.1 - 0.0072 15.8 5.8 0.012 15.1 5.8 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF812 PF05667.11 EIM79159.1 - 0.043 12.7 9.3 0.057 12.3 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 EIM79159.1 - 0.45 9.8 11.5 0.71 9.2 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 EIM79159.1 - 0.67 8.5 10.3 1.3 7.5 10.3 1.4 1 0 0 1 1 1 0 Macoilin family BBP1_C PF15272.6 EIM79159.1 - 1.9 8.3 7.4 3.2 7.5 7.4 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Jnk-SapK_ap_N PF09744.9 EIM79159.1 - 3 8.0 14.9 6.6 6.9 14.9 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1151 PF06625.11 EIM79159.1 - 4.5 7.2 12.4 4.9 7.1 10.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Gelsolin PF00626.22 EIM79161.1 - 0.013 15.4 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Gelsolin repeat Nse4_C PF08743.10 EIM79163.1 - 1.7e-25 89.1 1.9 2.3e-25 88.7 0.1 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EIM79163.1 - 2.1e-16 59.8 3.3 4.6e-16 58.7 3.3 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE ARPC4 PF05856.12 EIM79164.1 - 2.9e-80 267.7 6.5 3.2e-80 267.6 6.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) GPS2_interact PF15784.5 EIM79164.1 - 0.17 12.4 1.4 1.3 9.5 0.1 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain FKBP_C PF00254.28 EIM79165.1 - 2.7e-31 107.8 0.0 6.5e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EIM79165.1 - 1.2e-21 77.3 0.0 1.2e-21 77.3 0.0 2.5 2 1 0 2 2 2 1 Nucleoplasmin-like domain PAPA-1 PF04795.12 EIM79165.1 - 0.73 10.7 10.7 1.4 9.8 7.2 2.4 2 0 0 2 2 2 0 PAPA-1-like conserved region adh_short_C2 PF13561.6 EIM79166.1 - 3.3e-55 187.2 3.6 3.9e-55 186.9 3.1 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM79166.1 - 1.7e-42 145.1 0.9 2.4e-42 144.6 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM79166.1 - 4.5e-11 43.0 3.1 5.4e-10 39.5 3.1 2.1 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EIM79166.1 - 0.03 15.0 0.0 0.076 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SbcD_C PF12320.8 EIM79166.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain EntA_Immun PF08951.10 EIM79167.1 - 0.014 15.7 1.4 0.58 10.6 0.2 2.9 3 0 0 3 3 3 0 Enterocin A Immunity NOZZLE PF08744.10 EIM79167.1 - 0.12 11.9 2.8 0.079 12.4 1.3 1.4 1 1 1 2 2 2 0 Plant transcription factor NOZZLE V_ATPase_I PF01496.19 EIM79167.1 - 3.7 5.4 4.2 1.3 6.9 1.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family UDPGP PF01704.18 EIM79168.1 - 2.5e-199 662.1 0.9 2.8e-199 661.9 0.9 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UDPGP PF01704.18 EIM79169.1 - 1.3e-196 653.2 2.0 1.5e-196 653.0 2.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase OTCace_N PF02729.21 EIM79170.1 - 5.8e-43 146.4 0.0 8.3e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EIM79170.1 - 5.2e-41 140.3 0.0 2.3e-40 138.2 0.0 1.8 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ribosomal_S8e PF01201.22 EIM79171.1 - 1.5e-55 187.1 0.7 2.1e-55 186.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e GlutR_dimer PF00745.20 EIM79171.1 - 0.034 14.6 1.2 0.046 14.2 0.2 1.6 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Cylicin_N PF15241.6 EIM79171.1 - 0.079 13.1 0.6 0.17 12.0 0.5 1.6 1 1 0 1 1 1 0 Cylicin N-terminus SET PF00856.28 EIM79172.1 - 1.3e-11 45.2 0.1 1.7e-10 41.5 0.1 2.1 1 1 0 1 1 1 1 SET domain zf-C2H2 PF00096.26 EIM79173.1 - 2.9e-12 46.3 11.8 3.5e-06 27.2 1.8 3.1 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM79173.1 - 1.9e-08 34.4 5.5 0.0017 19.1 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM79173.1 - 6.1e-05 23.3 11.3 0.0039 17.6 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 EIM79173.1 - 0.002 18.0 1.4 0.15 12.0 0.2 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-BED PF02892.15 EIM79173.1 - 0.0037 17.3 0.8 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 BED zinc finger DUF3268 PF11672.8 EIM79173.1 - 0.0075 16.6 0.9 0.013 15.8 0.9 1.3 1 0 0 1 1 1 1 zinc-finger-containing domain zf-C2H2_6 PF13912.6 EIM79173.1 - 0.016 15.2 6.2 0.26 11.4 1.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EIM79173.1 - 0.034 14.5 3.0 0.061 13.7 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EIM79173.1 - 0.036 14.4 2.9 0.078 13.3 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EIM79173.1 - 0.061 13.6 0.6 0.11 12.8 0.6 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 EIM79173.1 - 0.064 13.0 5.2 3.7 7.4 0.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EIM79173.1 - 0.17 12.4 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 EIM79173.1 - 0.24 11.3 3.7 10 6.1 0.5 2.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain BolA PF01722.18 EIM79174.1 - 8.4e-30 102.9 0.2 1e-29 102.6 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein DNA_ligase_A_M PF01068.21 EIM79176.1 - 1.7e-42 145.4 0.0 1.6e-39 135.6 0.0 2.6 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIM79176.1 - 6.1e-32 111.3 0.0 1.3e-31 110.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EIM79176.1 - 1.6e-16 60.7 0.0 5.6e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region zf-C2H2 PF00096.26 EIM79177.1 - 9.4e-11 41.6 8.0 8.2e-05 22.8 0.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM79177.1 - 7.2e-08 32.6 6.7 0.00057 20.5 1.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM79177.1 - 4.5e-07 30.0 6.9 5.4e-06 26.6 0.8 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EIM79177.1 - 4.2e-05 23.7 2.8 0.0069 16.6 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EIM79177.1 - 0.00034 20.5 3.4 0.035 14.1 0.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EIM79177.1 - 0.00062 20.1 1.8 0.85 10.1 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type BolA PF01722.18 EIM79177.1 - 0.029 14.6 0.4 1.4 9.3 0.0 2.0 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_11 PF16622.5 EIM79177.1 - 0.036 13.8 1.7 1.4 8.8 0.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-MYST PF17772.1 EIM79177.1 - 0.12 12.0 1.4 0.6 9.8 0.3 1.9 1 1 1 2 2 2 0 MYST family zinc finger domain Ta0938 PF11494.8 EIM79177.1 - 0.13 12.6 1.0 10 6.4 0.0 2.0 1 1 1 2 2 2 0 Ta0938 zf_C2H2_ZHX PF18387.1 EIM79177.1 - 0.35 10.6 2.4 0.5 10.1 0.9 1.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 EIM79177.1 - 0.36 10.8 2.3 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Acetyltransf_1 PF00583.25 EIM79178.1 - 1.6e-11 44.5 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM79178.1 - 8.9e-09 35.7 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM79178.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EIM79178.1 - 8.1e-06 26.1 0.0 1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM79178.1 - 0.068 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 EIM79180.1 - 2e-64 217.5 0.0 2.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM79180.1 - 1.5e-36 126.0 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM79180.1 - 2.4e-05 23.8 0.0 9.1e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIM79180.1 - 3.8e-05 22.7 0.0 5.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RB_A PF01858.17 EIM79180.1 - 0.017 14.9 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain Seadorna_VP7 PF07387.11 EIM79180.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EIM79180.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM79180.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zn_clus PF00172.18 EIM79181.1 - 7.7e-08 32.3 9.7 1.3e-07 31.6 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.21 EIM79182.1 - 4.4e-62 210.1 0.1 1.7e-48 165.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EIM79182.1 - 0.00083 19.3 0.6 0.0034 17.3 0.6 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) SLAIN PF15301.6 EIM79182.1 - 0.02 14.1 3.2 0.031 13.5 3.2 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family RuvA_C PF07499.13 EIM79182.1 - 0.055 13.9 0.3 0.19 12.2 0.2 2.1 2 0 0 2 2 2 0 RuvA, C-terminal domain Pex14_N PF04695.13 EIM79182.1 - 0.14 12.8 2.2 0.3 11.7 2.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Choline_transpo PF04515.12 EIM79183.1 - 1.2e-78 264.7 13.7 1.2e-78 264.7 13.7 2.5 2 1 1 3 3 3 2 Plasma-membrane choline transporter Acyltransferase PF01553.21 EIM79184.1 - 2e-17 63.1 0.0 3.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase NUC173 PF08161.12 EIM79185.1 - 2.1e-59 200.6 0.2 2.6e-58 197.0 0.1 2.7 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.22 EIM79185.1 - 6.4e-05 22.9 0.4 0.36 11.2 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat MMS19_C PF12460.8 EIM79185.1 - 1.4 8.0 5.0 0.88 8.6 0.3 3.0 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal PAC2 PF09754.9 EIM79186.1 - 1.9e-17 64.0 0.0 3.3e-17 63.2 0.0 1.4 1 1 0 1 1 1 1 PAC2 family XPG_N PF00752.17 EIM79187.1 - 4.3e-16 59.2 0.0 7.8e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EIM79187.1 - 5.7e-14 52.2 0.0 1.3e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Hus1 PF04005.12 EIM79188.1 - 0.0031 16.7 0.2 0.0051 16.0 0.2 1.3 1 0 0 1 1 1 1 Hus1-like protein zf-MYND PF01753.18 EIM79190.1 - 1.1e-08 35.0 7.5 3.6e-08 33.3 7.6 1.9 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM79190.1 - 0.064 13.6 5.1 0.13 12.5 5.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF4121 PF13497.6 EIM79190.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Acyl_transf_1 PF00698.21 EIM79193.1 - 0.012 15.2 0.1 0.012 15.2 0.1 1.0 1 0 0 1 1 1 0 Acyl transferase domain DUF4113 PF13438.6 EIM79193.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) DUF1643 PF07799.12 EIM79193.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Ion_trans PF00520.31 EIM79195.1 - 5e-28 98.0 28.2 5.4e-17 61.8 8.0 3.2 2 1 0 2 2 2 2 Ion transport protein LRR_adjacent PF08191.11 EIM79197.1 - 0.047 13.9 0.1 0.079 13.2 0.1 1.5 1 1 0 1 1 1 0 LRR adjacent Sec34 PF04136.15 EIM79198.1 - 7e-47 159.1 0.0 1.7e-46 157.8 0.0 1.7 1 0 0 1 1 1 1 Sec34-like family DUF87 PF01935.17 EIM79200.1 - 0.082 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain DUF1752 PF08550.10 EIM79201.1 - 3.4e-14 52.4 0.8 4.3e-14 52.0 0.8 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3141 PF11339.8 EIM79203.1 - 0.077 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Helitron_like_N PF14214.6 EIM79207.1 - 8.2e-22 78.3 0.0 9.4e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus FAD_SOX PF18371.1 EIM79208.1 - 0.018 15.4 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase EcoRI PF02963.16 EIM79209.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRI PIF1 PF05970.14 EIM79210.1 - 3.2e-07 29.9 0.0 0.0001 21.6 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase TP2 PF01254.18 EIM79212.1 - 0.58 10.8 4.1 2 9.0 4.1 1.9 1 0 0 1 1 1 0 Nuclear transition protein 2 Pkinase_fungal PF17667.1 EIM79213.1 - 5.5e-36 124.2 0.0 9.7e-27 93.8 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase PHD PF00628.29 EIM79214.1 - 1.9e-06 27.7 11.5 3.6e-06 26.8 11.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIM79214.1 - 0.37 10.4 8.1 0.7 9.5 8.1 1.4 1 0 0 1 1 1 0 PHD-finger APH PF01636.23 EIM79217.1 - 3.2e-13 50.2 0.1 6e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EIM79217.1 - 0.031 13.1 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MMR_HSR1 PF01926.23 EIM79219.1 - 1.3e-06 28.5 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM79219.1 - 4e-05 23.6 0.2 0.00026 21.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 EIM79219.1 - 0.0019 17.5 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 EIM79219.1 - 0.0043 17.4 0.1 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM79219.1 - 0.0092 16.3 0.1 0.032 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 EIM79219.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 EIM79219.1 - 0.024 14.7 0.5 0.44 10.6 0.1 2.5 2 1 0 2 2 2 0 Dynamin family AAA_21 PF13304.6 EIM79219.1 - 0.034 14.0 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EIM79219.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 EIM79219.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EIM79219.1 - 0.11 12.1 0.0 0.34 10.4 0.0 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EIM79219.1 - 0.11 12.1 0.4 0.53 9.8 0.0 2.2 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_29 PF13555.6 EIM79219.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TauD PF02668.16 EIM79223.1 - 3e-55 187.9 0.5 4e-55 187.5 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactonase PF10282.9 EIM79226.1 - 9.2e-33 113.9 0.1 1.3e-32 113.4 0.1 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cutinase PF01083.22 EIM79227.1 - 5.3e-49 166.6 0.9 6e-49 166.4 0.9 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EIM79227.1 - 0.0012 18.4 0.2 0.0018 17.9 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain SNF2_N PF00176.23 EIM79228.1 - 2.4e-35 121.9 0.0 2.8e-31 108.5 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM79228.1 - 2.9e-15 56.6 0.0 6.9e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM79228.1 - 2.4e-08 34.2 0.0 4.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIM79228.1 - 0.00025 20.9 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2235 PF09994.9 EIM79229.1 - 4.5e-40 137.8 0.1 1.2e-38 133.1 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) H_lectin PF09458.10 EIM79230.1 - 2.9e-40 136.3 2.3 9.6e-15 54.5 0.1 3.1 3 0 0 3 3 3 3 H-type lectin domain WD40 PF00400.32 EIM79232.1 - 1.1e-51 171.7 25.0 5.9e-10 39.6 0.6 7.1 6 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79232.1 - 7.4e-24 83.9 2.4 0.00017 21.8 0.0 5.4 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM79232.1 - 4.9e-07 29.0 3.4 0.75 8.7 0.4 4.7 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EIM79232.1 - 3.5e-06 26.0 0.4 2.1 7.0 0.0 4.1 1 1 3 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 EIM79232.1 - 7.2e-06 24.9 3.6 0.5 9.0 0.0 4.3 3 2 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM79232.1 - 1.2e-05 24.8 0.1 0.2 11.0 0.0 3.4 3 1 1 4 4 4 3 WD40-like domain BBS2_Mid PF14783.6 EIM79232.1 - 4.6e-05 23.4 0.0 2.9 8.0 0.0 4.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 EIM79232.1 - 9.6e-05 22.2 0.1 15 5.7 0.0 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EIM79232.1 - 0.0045 15.6 0.3 0.28 9.7 0.1 2.4 2 0 0 2 2 2 1 Cytochrome D1 heme domain Frtz PF11768.8 EIM79232.1 - 0.0052 15.2 0.7 1.5 7.1 0.2 3.3 2 2 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 EIM79232.1 - 0.006 15.4 0.2 5.8 5.6 0.1 3.7 2 2 1 3 3 3 2 Prolyl oligopeptidase, N-terminal beta-propeller domain ChapFlgA PF13144.6 EIM79232.1 - 0.011 15.8 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Chaperone for flagella basal body P-ring formation DUF1652 PF07865.11 EIM79232.1 - 0.015 15.1 0.0 2.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) DUF4072 PF13284.6 EIM79232.1 - 0.051 14.0 0.4 19 5.8 0.0 3.3 4 0 0 4 4 3 0 Domain of unknown function (DUF4072) PQQ_3 PF13570.6 EIM79232.1 - 0.063 13.8 0.0 11 6.6 0.0 3.0 2 2 0 2 2 2 0 PQQ-like domain Phage_Mu_Gp45 PF06890.12 EIM79232.1 - 0.087 12.6 0.0 16 5.3 0.0 3.2 2 1 1 3 3 3 0 Bacteriophage Mu Gp45 protein Calici_coat_C PF08435.11 EIM79232.1 - 0.15 11.6 0.0 16 4.9 0.0 2.3 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal Amidohydro_1 PF01979.20 EIM79233.1 - 3.3e-14 53.0 0.1 7.9e-13 48.4 0.1 2.8 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM79233.1 - 3.9e-12 46.4 1.3 2e-07 30.9 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family DUF4470 PF14737.6 EIM79235.1 - 9.8e-21 73.8 0.0 2.3e-20 72.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EIM79235.1 - 2.6e-06 27.4 14.3 4.4e-06 26.7 14.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EIM79235.1 - 1.6 8.9 5.7 3.5 7.8 5.7 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EIM79236.1 - 3.9e-06 26.8 16.2 7.7e-06 25.9 16.2 1.5 1 0 0 1 1 1 1 MYND finger DUF2267 PF10025.9 EIM79236.1 - 0.026 14.8 0.1 0.32 11.3 0.0 2.6 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) OAM_alpha PF16552.5 EIM79236.1 - 0.08 12.8 1.2 0.45 10.4 0.0 2.5 3 0 0 3 3 3 0 D-ornithine 4,5-aminomutase alpha-subunit Pkinase PF00069.25 EIM79236.1 - 0.086 12.2 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain DUF1128 PF06569.11 EIM79236.1 - 0.087 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) zf-C6H2 PF15801.5 EIM79236.1 - 0.16 12.3 9.8 0.32 11.3 9.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Kdo PF06293.14 EIM79237.1 - 0.0034 16.8 1.6 0.0058 16.0 0.8 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3638 PF12340.8 EIM79238.1 - 1.7e-81 272.9 0.1 3.9e-81 271.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EIM79238.1 - 3.9e-16 58.1 0.1 9.4e-16 56.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) SH3_6 PF12913.7 EIM79239.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) Sod_Fe_C PF02777.18 EIM79240.1 - 4e-37 126.5 0.3 7.3e-37 125.6 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EIM79240.1 - 9.2e-32 109.4 5.2 9.9e-32 109.3 3.9 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ocnus PF05005.15 EIM79240.1 - 0.042 14.0 0.5 0.42 10.8 0.2 2.2 1 1 0 2 2 2 0 Janus/Ocnus family (Ocnus) GTP_EFTU_D3 PF03143.17 EIM79241.1 - 0.21 11.9 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain Methyltransf_10 PF05971.12 EIM79242.1 - 3.3e-56 190.8 0.0 4.9e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EIM79242.1 - 1.4e-05 24.7 0.0 3.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EIM79242.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIM79242.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EIM79242.1 - 0.011 16.4 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EIM79242.1 - 0.072 13.7 0.0 0.22 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 EIM79242.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrmK PF04816.12 EIM79242.1 - 0.25 10.9 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Abhydrolase_1 PF00561.20 EIM79243.1 - 6.2e-27 94.9 0.0 3.7e-26 92.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM79243.1 - 7.6e-15 56.1 0.1 1.3e-14 55.4 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM79243.1 - 2.6e-10 40.0 0.0 7.9e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 EIM79243.1 - 3.7e-09 35.7 0.0 5.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 EIM79243.1 - 0.054 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein F-box-like PF12937.7 EIM79244.1 - 1.8e-06 27.7 0.8 6.7e-06 25.9 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EIM79245.1 - 3.7e-05 23.5 0.3 9.2e-05 22.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like UCR_hinge PF02320.16 EIM79246.1 - 3.5e-23 81.6 4.7 7.4e-23 80.5 4.7 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC27 PF09507.10 EIM79246.1 - 0.082 12.3 6.9 0.083 12.3 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GOLD_2 PF13897.6 EIM79246.1 - 0.19 12.2 2.3 0.27 11.7 2.3 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DNA_pol_phi PF04931.13 EIM79246.1 - 1.2 7.2 9.0 1.2 7.1 9.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi ORC_WH_C PF18137.1 EIM79246.1 - 1.4 9.0 7.3 1.6 8.8 6.8 1.3 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal CDC45 PF02724.14 EIM79246.1 - 8.6 4.5 6.2 9 4.5 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein BBE PF08031.12 EIM79248.1 - 3.2e-05 23.9 0.1 7.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EIM79248.1 - 0.0017 18.1 0.0 0.005 16.6 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain DUF4755 PF15947.5 EIM79248.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4755) O-FucT PF10250.9 EIM79249.1 - 4.9e-08 33.1 0.0 0.0009 19.0 0.0 3.1 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase CAS_CSE1 PF03378.15 EIM79251.1 - 1.3e-118 396.3 0.0 2.3e-118 395.5 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EIM79251.1 - 8.9e-82 274.8 0.0 1.4e-81 274.2 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EIM79251.1 - 4.4e-11 42.5 0.2 3.7e-10 39.6 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EIM79251.1 - 0.0013 18.8 1.1 0.021 14.9 0.0 3.3 4 0 0 4 4 4 1 Exportin 1-like protein Ufd2P_core PF10408.9 EIM79251.1 - 0.014 14.0 0.2 0.022 13.4 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core CelTOS PF18659.1 EIM79253.1 - 0.048 14.1 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites DUF3638 PF12340.8 EIM79254.1 - 1.2e-83 279.9 0.6 3.6e-83 278.3 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EIM79254.1 - 1.2e-15 56.6 0.0 3.4e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF2992 PF11208.8 EIM79254.1 - 0.039 14.2 0.2 0.099 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2587 PF10759.9 EIM79255.1 - 0.11 12.1 0.7 0.22 11.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) MFS_1 PF07690.16 EIM79256.1 - 2.2e-22 79.5 51.6 9.8e-21 74.0 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 EIM79257.1 - 9.3e-06 25.4 0.1 2.4e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like NAD_binding_4 PF07993.12 EIM79259.1 - 1.8e-08 33.9 0.0 2.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein p450 PF00067.22 EIM79260.1 - 2e-59 201.6 0.0 3.1e-59 201.0 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 EIM79261.1 - 0.0092 16.7 0.0 0.031 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM79261.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EIM79261.1 - 0.026 15.2 0.0 0.046 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIM79261.1 - 0.064 14.0 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EIM79261.1 - 0.095 12.5 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 EIM79262.1 - 3.1e-13 49.6 0.2 3.4e-13 49.5 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM79262.1 - 9e-06 25.7 0.1 1e-05 25.5 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EIM79262.1 - 2.6e-05 23.9 0.4 4.4e-05 23.2 0.3 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM79262.1 - 0.00075 19.0 0.1 0.00088 18.8 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EIM79262.1 - 0.0036 17.6 0.1 0.0044 17.3 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EIM79262.1 - 0.0059 16.1 0.1 0.0072 15.8 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EIM79262.1 - 0.008 16.2 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SBP_bac_3 PF00497.20 EIM79262.1 - 0.028 13.9 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Trp_halogenase PF04820.14 EIM79267.1 - 2.8e-29 102.3 0.3 1e-15 57.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EIM79267.1 - 1e-11 44.7 0.1 5.2e-11 42.4 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM79267.1 - 1.6e-07 30.8 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM79267.1 - 4e-06 27.0 0.6 2e-05 24.7 0.1 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EIM79267.1 - 2.8e-05 23.7 0.1 8.4e-05 22.1 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EIM79267.1 - 0.00011 21.4 0.1 0.00018 20.8 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EIM79267.1 - 0.00028 19.7 0.0 0.00045 19.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EIM79267.1 - 0.00041 20.0 0.1 0.002 17.8 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM79267.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EIM79267.1 - 0.0037 16.5 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EIM79267.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM79267.1 - 0.03 14.9 0.0 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM79267.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EIM79267.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EIM79267.1 - 0.18 12.2 0.0 0.55 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Methyltransf_2 PF00891.18 EIM79268.1 - 1.8e-21 76.4 0.0 5.7e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 EIM79268.1 - 0.00017 21.4 0.0 0.0004 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM79268.1 - 0.00072 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EIM79268.1 - 0.0017 19.0 0.0 0.0054 17.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EIM79268.1 - 0.0034 17.1 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DOT1 PF08123.13 EIM79268.1 - 0.037 13.5 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 EIM79268.1 - 0.098 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIM79268.1 - 0.15 12.8 0.0 0.64 10.8 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 EIM79268.1 - 0.15 12.7 0.0 0.63 10.7 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Transposase_21 PF02992.14 EIM79269.1 - 1.7e-06 27.5 0.0 4.9e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 EIM79269.1 - 0.16 11.6 0.1 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) RecR PF02132.15 EIM79269.1 - 0.22 11.1 2.6 0.48 10.0 2.6 1.6 1 0 0 1 1 1 0 RecR protein HSP70 PF00012.20 EIM79271.1 - 2.6e-56 191.1 0.2 3.1e-54 184.2 1.3 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EIM79271.1 - 6e-08 31.9 1.1 8.5e-08 31.4 1.1 1.1 1 0 0 1 1 1 1 MreB/Mbl protein p450 PF00067.22 EIM79276.1 - 1.1e-61 209.0 0.0 5.6e-42 144.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DPBB_1 PF03330.18 EIM79277.1 - 6.9e-05 23.0 0.0 0.0001 22.5 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase OTT_1508_deam PF14441.6 EIM79278.1 - 0.0022 18.0 3.3 0.0057 16.6 3.3 1.8 1 1 0 1 1 1 1 OTT_1508-like deaminase MMU163 PF17119.5 EIM79278.1 - 0.056 12.6 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Dicty_REP PF05086.12 EIM79280.1 - 0.45 8.4 1.3 0.58 8.1 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fer2_BFD PF04324.15 EIM79281.1 - 0.0037 17.6 0.4 0.014 15.8 0.1 2.1 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Alpha_GJ PF03229.13 EIM79281.1 - 0.0091 16.6 1.9 0.027 15.0 0.1 2.4 2 0 0 2 2 2 1 Alphavirus glycoprotein J MGC-24 PF05283.11 EIM79281.1 - 0.015 15.7 0.2 0.015 15.7 0.2 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4293 PF14126.6 EIM79281.1 - 0.077 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) p450 PF00067.22 EIM79282.1 - 3.6e-57 194.1 0.0 6.2e-51 173.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_28 PF00295.17 EIM79283.1 - 2.9e-25 89.0 5.8 4.2e-25 88.5 5.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EIM79283.1 - 0.00066 19.6 12.0 0.021 14.7 1.6 3.3 1 1 1 2 2 2 2 Pectate lyase superfamily protein Peptidase_M28 PF04389.17 EIM79284.1 - 1.3e-35 122.9 0.1 4.4e-35 121.2 0.0 1.9 3 0 0 3 3 3 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIM79284.1 - 0.0078 15.9 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DDE_Tnp_ISL3 PF01610.17 EIM79284.1 - 0.022 14.5 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Transposase Polysacc_lyase PF14099.6 EIM79285.1 - 0.00092 19.1 0.1 0.08 12.8 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide lyase GLTP PF08718.11 EIM79286.1 - 1.1e-38 132.8 0.0 1.4e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Fungal_trans PF04082.18 EIM79288.1 - 9.8e-21 74.0 0.0 1.7e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM79288.1 - 2.2e-05 24.5 14.5 3.9e-05 23.7 14.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.6 EIM79288.1 - 0.19 11.5 0.0 0.45 10.2 0.0 1.6 1 0 0 1 1 1 0 TPR repeat FAD_binding_3 PF01494.19 EIM79290.1 - 1.5e-24 86.9 0.0 2.7e-24 86.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM79290.1 - 7.6e-05 22.9 0.4 0.00022 21.4 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM79290.1 - 0.00016 21.4 0.5 0.00033 20.4 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM79290.1 - 0.00051 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EIM79290.1 - 0.0033 16.5 0.1 0.014 14.5 0.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.10 EIM79290.1 - 0.019 14.0 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EIM79290.1 - 0.03 13.6 0.1 0.25 10.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM79290.1 - 0.22 10.3 0.7 13 4.5 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase SlyX PF04102.12 EIM79293.1 - 0.057 14.0 0.2 0.1 13.3 0.2 1.4 1 0 0 1 1 1 0 SlyX Thioredoxin_10 PF17991.1 EIM79294.1 - 0.025 15.1 0.0 0.035 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin like C-terminal domain CBM60 PF16841.5 EIM79294.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Zn_clus PF00172.18 EIM79297.1 - 0.18 12.0 9.7 0.42 10.8 9.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PCP_red PF08369.10 EIM79297.1 - 6.3 7.1 6.2 9.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit WD40 PF00400.32 EIM79298.1 - 5e-75 245.5 22.0 2.6e-09 37.6 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79298.1 - 4.9e-28 97.3 0.0 0.0023 18.2 0.0 7.6 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM79298.1 - 1.7e-15 56.8 2.3 0.26 10.2 0.0 7.0 1 1 6 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIM79298.1 - 5.9e-11 42.0 3.8 0.53 10.3 0.0 7.1 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EIM79298.1 - 2.4e-10 40.6 0.0 1.3e-05 25.2 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EIM79298.1 - 5.9e-10 38.4 0.4 0.41 9.2 0.0 6.3 2 1 5 8 8 8 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM79298.1 - 1.7e-09 37.4 0.0 0.09 12.1 0.0 4.5 5 0 0 5 5 5 3 WD40-like domain Cytochrom_D1 PF02239.16 EIM79298.1 - 4.9e-06 25.3 0.1 0.0099 14.4 0.0 2.6 1 1 1 3 3 3 2 Cytochrome D1 heme domain Gmad1 PF10647.9 EIM79298.1 - 0.00033 20.5 0.9 3.9 7.2 0.0 3.9 1 1 2 4 4 4 2 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.6 EIM79298.1 - 0.00099 18.5 1.7 6.4 6.0 0.0 5.3 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 EIM79298.1 - 0.0091 15.1 0.0 5.6 5.9 0.0 3.5 2 2 2 4 4 4 1 VID27 C-terminal WD40-like domain nos_propeller PF18764.1 EIM79298.1 - 0.0093 15.9 0.0 14 5.7 0.0 3.8 4 1 0 4 4 4 0 Nitrous oxide reductase propeller repeat PQQ PF01011.21 EIM79298.1 - 0.019 14.8 0.1 13 5.9 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat SdiA-regulated PF06977.11 EIM79298.1 - 0.029 13.6 0.0 0.35 10.0 0.0 2.3 1 1 2 3 3 3 0 SdiA-regulated MMS1_N PF10433.9 EIM79298.1 - 0.1 11.2 0.0 7.2 5.1 0.0 2.7 2 1 1 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Frtz PF11768.8 EIM79298.1 - 0.12 10.7 0.0 21 3.3 0.0 3.4 2 2 3 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 EIM79298.1 - 0.77 9.5 13.0 56 3.5 0.1 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF2235 PF09994.9 EIM79299.1 - 1e-63 215.4 0.1 1.3e-63 215.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-MYND PF01753.18 EIM79300.1 - 2.8e-10 40.1 7.7 7.1e-10 38.8 7.7 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM79300.1 - 1.1 9.7 8.0 2.2 8.6 8.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ashwin PF15323.6 EIM79301.1 - 6.8 6.6 11.0 0.86 9.6 3.4 2.1 2 0 0 2 2 2 0 Developmental protein DnaJ_CXXCXGXG PF00684.19 EIM79302.1 - 0.0033 17.7 4.9 0.28 11.6 0.4 2.4 2 0 0 2 2 2 2 DnaJ central domain SQS_PSY PF00494.19 EIM79305.1 - 9.9e-33 113.7 0.0 2e-32 112.8 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase DUF3789 PF12664.7 EIM79305.1 - 0.11 12.2 4.3 0.22 11.3 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) MAP65_ASE1 PF03999.12 EIM79307.1 - 0.58 8.8 3.3 0.32 9.6 1.5 1.4 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) DUF3903 PF13043.6 EIM79308.1 - 0.044 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) Importin_rep_4 PF18808.1 EIM79309.1 - 0.11 12.8 1.1 2.6 8.4 0.4 2.5 2 0 0 2 2 2 0 Importin repeat VEFS-Box PF09733.9 EIM79309.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 VEFS-Box of polycomb protein HNH_2 PF13391.6 EIM79310.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease RCC1 PF00415.18 EIM79311.1 - 5e-38 129.5 15.5 5.7e-14 52.5 0.0 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIM79311.1 - 2e-15 56.1 19.9 2.5e-07 30.3 0.6 5.7 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 EIM79311.1 - 4.5e-09 36.1 5.4 4.5e-09 36.1 5.4 2.4 3 0 0 3 3 3 1 PHD-finger Reg_prop PF07494.11 EIM79311.1 - 0.094 13.0 0.2 8.4 7.0 0.0 3.8 4 0 0 4 4 4 0 Two component regulator propeller PHD_2 PF13831.6 EIM79311.1 - 0.8 9.3 7.4 1.9 8.1 0.2 3.1 3 0 0 3 3 3 0 PHD-finger DAO PF01266.24 EIM79312.1 - 2.9e-34 119.2 0.6 3.5e-34 118.9 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM79312.1 - 3.5e-05 24.0 0.5 9.4e-05 22.6 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM79312.1 - 0.0091 16.0 0.1 0.039 13.9 0.2 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF3498 PF12004.8 EIM79312.1 - 0.037 13.2 1.2 0.058 12.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Thi4 PF01946.17 EIM79312.1 - 0.06 12.6 0.1 0.091 12.0 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 EIM79312.1 - 0.072 12.4 0.2 0.37 10.0 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EIM79312.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EIM79312.1 - 0.27 10.0 0.1 0.39 9.5 0.1 1.2 1 0 0 1 1 1 0 MCRA family Chordopox_A13L PF05961.11 EIM79314.1 - 0.053 13.7 0.5 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein adh_short PF00106.25 EIM79315.1 - 6.3e-35 120.4 0.0 8.2e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79315.1 - 4.1e-27 95.2 0.3 6.4e-27 94.6 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79315.1 - 8.1e-05 22.6 0.1 0.00016 21.7 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EIM79315.1 - 0.0015 18.1 0.1 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EIM79315.1 - 0.0052 17.3 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EIM79315.1 - 0.016 15.5 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain PALP PF00291.25 EIM79315.1 - 0.032 13.6 0.2 0.055 12.9 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme CBP_BcsQ PF06564.12 EIM79315.1 - 0.037 13.5 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NAD_binding_2 PF03446.15 EIM79315.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Wax2_C PF12076.8 EIM79315.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain DUF3341 PF11821.8 EIM79317.1 - 0.25 11.0 2.5 0.4 10.3 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) FA_hydroxylase PF04116.13 EIM79318.1 - 5.9e-17 62.3 23.4 5.9e-17 62.3 23.4 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.25 EIM79319.1 - 3.5e-21 75.6 0.2 1.2e-20 73.8 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79319.1 - 2.5e-17 63.2 0.2 4.8e-17 62.3 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FmdE PF02663.14 EIM79319.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Methyltransf_15 PF09445.10 EIM79320.1 - 2.9e-37 127.8 0.0 7.6e-36 123.2 0.0 2.3 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EIM79320.1 - 9.6e-07 29.4 0.0 1.8e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EIM79320.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EIM79320.1 - 0.00026 20.8 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM79320.1 - 0.00042 20.9 0.0 0.00074 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EIM79320.1 - 0.008 15.8 0.0 0.53 9.9 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 EIM79320.1 - 0.0086 16.0 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EIM79320.1 - 0.03 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PutA_N PF18083.1 EIM79320.1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Proline utilization A N-terminal domain UPF0020 PF01170.18 EIM79320.1 - 0.16 11.6 0.1 0.93 9.1 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 XFP_N PF09364.10 EIM79320.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain PrmA PF06325.13 EIM79320.1 - 0.23 10.8 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cupin_2 PF07883.11 EIM79325.1 - 1.6e-06 27.7 0.2 2.6e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EIM79325.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin GCIP PF13324.6 EIM79326.1 - 0.028 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Serglycin PF04360.12 EIM79328.1 - 5.1 7.0 9.4 5.6 6.9 7.7 1.8 1 1 0 2 2 2 0 Serglycin Phage_GP20 PF06810.11 EIM79330.1 - 0.4 10.5 6.0 2.4 7.9 0.2 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 EIM79330.1 - 0.68 10.1 9.4 0.66 10.1 0.5 2.8 2 0 0 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 EIM79330.1 - 0.99 9.7 8.2 23 5.2 8.0 2.9 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 EIM79330.1 - 3 7.1 8.5 10 5.4 8.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RCC1 PF00415.18 EIM79331.1 - 3.4e-16 59.6 9.3 0.00013 22.5 0.0 5.9 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EIM79331.1 - 3.9e-11 43.3 0.4 3.2e-10 40.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM79331.1 - 2.5e-09 37.6 0.1 8.5e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 EIM79331.1 - 3.4e-07 29.9 0.0 3.4e-07 29.9 0.0 4.5 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EIM79331.1 - 4.7e-07 30.0 0.0 0.0029 17.8 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain Ank PF00023.30 EIM79331.1 - 4.9e-07 29.9 0.4 0.0003 21.1 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EIM79331.1 - 1.2e-06 28.4 1.0 0.077 13.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EIM79331.1 - 0.00033 20.9 0.9 0.0031 17.8 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) EKLF_TAD1 PF16832.5 EIM79331.1 - 0.029 14.2 5.6 0.096 12.6 5.6 1.9 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Lipase_3 PF01764.25 EIM79332.1 - 1.8e-32 112.1 0.0 2.7e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) MNSV_P7B PF06692.11 EIM79332.1 - 0.01 15.8 0.2 0.026 14.5 0.2 1.7 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein Hydrolase_4 PF12146.8 EIM79332.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EIM79332.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 EIM79332.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative esterase DUF1899 PF08953.11 EIM79333.1 - 1e-27 95.8 0.1 2.3e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EIM79333.1 - 2.1e-17 63.1 7.0 5.2e-05 23.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_4 PF16300.5 EIM79333.1 - 4e-15 55.4 0.4 1.1e-14 54.1 0.4 1.7 1 0 0 1 1 1 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 EIM79333.1 - 5.7e-07 29.8 0.1 0.067 13.5 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Csm1_N PF18504.1 EIM79333.1 - 0.21 11.9 3.1 0.34 11.3 3.1 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF3275 PF11679.8 EIM79333.1 - 1.1 9.1 3.4 1.9 8.4 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) FAD_binding_3 PF01494.19 EIM79334.1 - 1.7e-19 70.3 0.0 2.9e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM79334.1 - 6.1e-08 32.8 0.2 1.3e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM79334.1 - 7.2e-08 32.4 2.0 3.8e-06 26.7 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM79334.1 - 1.5e-06 27.6 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM79334.1 - 3.6e-05 23.1 0.3 0.00051 19.4 0.3 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM79334.1 - 0.0022 17.1 0.0 0.077 12.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EIM79334.1 - 0.0047 15.7 0.1 0.0069 15.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EIM79334.1 - 0.006 15.9 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EIM79334.1 - 0.0076 15.1 0.0 1.1 8.0 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.22 EIM79334.1 - 0.045 12.8 0.3 0.083 12.0 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EIM79334.1 - 0.047 14.3 0.2 0.14 12.7 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM79334.1 - 0.072 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM79334.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM79334.1 - 0.11 12.4 0.3 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 EIM79334.1 - 0.18 11.2 0.5 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase GCV_T PF01571.21 EIM79335.1 - 3.7e-82 275.6 0.0 4.5e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EIM79335.1 - 6e-22 77.4 0.1 1.2e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain AAA_2 PF07724.14 EIM79339.1 - 5.5e-47 160.0 0.0 6.1e-44 150.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EIM79339.1 - 1.2e-32 112.0 0.5 1.2e-32 112.0 0.5 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EIM79339.1 - 3.8e-21 74.9 2.8 1.4e-20 73.1 0.2 3.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EIM79339.1 - 8.4e-21 74.8 0.1 6.5e-11 42.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM79339.1 - 2.8e-17 63.0 0.0 9.7e-11 41.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIM79339.1 - 6.9e-11 42.8 6.1 3.6e-05 24.2 0.1 4.3 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EIM79339.1 - 1.7e-09 38.1 2.0 0.0012 19.1 0.0 4.2 4 2 0 4 4 3 2 AAA domain Sigma54_activat PF00158.26 EIM79339.1 - 3.1e-08 33.5 0.0 1.5e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EIM79339.1 - 3.3e-07 29.9 0.1 0.13 11.6 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EIM79339.1 - 1.6e-06 27.7 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EIM79339.1 - 2.1e-06 28.3 0.0 0.062 13.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EIM79339.1 - 6.8e-06 26.1 0.0 0.042 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EIM79339.1 - 8.2e-06 25.7 0.3 0.16 11.7 0.0 3.0 4 0 0 4 4 3 2 IstB-like ATP binding protein ABC_tran PF00005.27 EIM79339.1 - 1.1e-05 26.0 1.1 0.092 13.3 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.6 EIM79339.1 - 2.5e-05 24.1 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EIM79339.1 - 4.5e-05 23.3 0.4 0.54 10.0 0.0 3.5 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EIM79339.1 - 7.1e-05 23.1 0.2 0.45 10.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 EIM79339.1 - 7.5e-05 22.8 7.6 0.11 12.4 0.0 4.4 3 2 2 5 5 4 1 ATPase domain predominantly from Archaea Roc PF08477.13 EIM79339.1 - 0.00014 22.1 0.0 0.31 11.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EIM79339.1 - 0.00017 21.9 0.0 0.85 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 EIM79339.1 - 0.00026 21.0 0.0 0.79 9.6 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EIM79339.1 - 0.0018 18.1 2.8 4 7.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM79339.1 - 0.0029 17.3 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 EIM79339.1 - 0.0044 17.0 0.0 0.83 9.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Bac_DnaA PF00308.18 EIM79339.1 - 0.0053 16.6 0.0 3.6 7.4 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_30 PF13604.6 EIM79339.1 - 0.0066 16.2 0.0 0.95 9.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EIM79339.1 - 0.0068 16.3 0.3 3.9 7.4 0.0 3.6 4 0 0 4 4 3 0 NTPase T2SSE PF00437.20 EIM79339.1 - 0.0068 15.5 0.0 0.16 11.0 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EIM79339.1 - 0.0075 15.9 0.2 0.45 10.0 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_19 PF13245.6 EIM79339.1 - 0.0098 16.2 0.1 0.41 11.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 EIM79339.1 - 0.011 15.8 0.0 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EIM79339.1 - 0.012 15.2 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EIM79339.1 - 0.019 14.8 0.0 0.8 9.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EIM79339.1 - 0.021 15.0 0.0 4.6 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 EIM79339.1 - 0.025 14.4 0.0 0.39 10.5 0.0 2.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_17 PF13207.6 EIM79339.1 - 0.03 14.7 0.1 14 6.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain FapA PF03961.13 EIM79339.1 - 0.033 12.8 2.1 0.065 11.8 2.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A ResIII PF04851.15 EIM79339.1 - 0.044 13.8 0.1 29 4.6 0.0 3.3 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EIM79339.1 - 0.049 13.5 0.0 21 5.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EIM79339.1 - 0.075 12.8 0.0 0.92 9.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EIM79339.1 - 0.084 12.3 1.1 14 5.0 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_11 PF13086.6 EIM79339.1 - 0.15 11.8 6.6 2.4 7.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Cob_adeno_trans PF01923.18 EIM79339.1 - 0.36 10.9 5.7 0.73 10.0 2.2 2.7 2 1 1 3 3 3 0 Cobalamin adenosyltransferase CENP-F_leu_zip PF10473.9 EIM79339.1 - 0.46 10.5 18.7 0.14 12.2 15.2 2.0 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_23 PF13476.6 EIM79339.1 - 0.91 10.0 0.0 0.91 10.0 0.0 3.8 3 1 0 3 3 2 0 AAA domain UPF0242 PF06785.11 EIM79339.1 - 2.4 8.2 11.5 4.3 7.4 11.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SE PF08491.10 EIM79340.1 - 9.1e-94 313.6 0.0 1.2e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EIM79340.1 - 1.4e-07 31.1 0.0 8.9e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM79340.1 - 5.2e-07 29.6 0.0 0.00051 19.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM79340.1 - 0.0046 16.2 0.0 0.077 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM79340.1 - 0.013 14.6 0.1 0.038 13.1 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EIM79340.1 - 0.014 15.6 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM79340.1 - 0.038 14.0 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EIM79340.1 - 0.081 12.2 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 EIM79340.1 - 0.16 10.8 0.0 4.6 6.0 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 EIM79340.1 - 0.22 10.6 3.2 3.6 6.6 3.5 2.1 2 0 0 2 2 2 0 FAD binding domain DnaJ PF00226.31 EIM79342.1 - 1.2e-09 38.1 0.1 1.2e-09 38.1 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain NAD_binding_10 PF13460.6 EIM79343.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM79343.1 - 0.00048 19.7 0.0 0.001 18.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EIM79343.1 - 0.014 15.8 0.1 0.024 15.0 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EIM79343.1 - 0.033 13.4 0.1 1.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.6 EIM79344.1 - 1e-06 28.8 0.1 2e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EIM79344.1 - 6.5e-05 23.4 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_10 PF00331.20 EIM79344.1 - 0.0057 15.8 0.1 0.0076 15.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Epimerase PF01370.21 EIM79344.1 - 0.016 14.7 0.0 0.039 13.4 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 EIM79344.1 - 0.055 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 HIM1 TPR_MLP1_2 PF07926.12 EIM79346.1 - 0.0008 19.5 5.5 0.0008 19.5 5.5 3.2 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein KxDL PF10241.9 EIM79346.1 - 0.046 14.0 1.4 0.14 12.4 0.9 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein Sec8_exocyst PF04048.14 EIM79346.1 - 0.093 12.6 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Ploopntkinase3 PF18751.1 EIM79346.1 - 0.13 12.2 2.8 0.25 11.2 2.8 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Halogen_Hydrol PF10112.9 EIM79346.1 - 0.14 12.1 0.5 0.4 10.7 0.5 1.8 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Jnk-SapK_ap_N PF09744.9 EIM79346.1 - 0.73 10.0 24.9 0.12 12.6 9.5 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMCO5 PF14992.6 EIM79346.1 - 1.5 8.4 9.6 2.2 7.8 9.6 1.1 1 0 0 1 1 1 0 TMCO5 family FRB_dom PF08771.11 EIM79346.1 - 5.2 7.5 6.2 5.4 7.5 0.1 3.0 2 1 1 3 3 3 0 FKBP12-rapamycin binding domain ADIP PF11559.8 EIM79346.1 - 5.7 7.0 23.8 0.58 10.2 5.3 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding zf-CCHC PF00098.23 EIM79348.1 - 2.5e-05 24.1 1.8 5.4e-05 23.1 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIM79348.1 - 0.00016 21.4 1.8 0.00028 20.6 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EIM79348.1 - 0.00024 21.0 0.7 0.0005 20.0 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Bep_C_terminal PF17841.1 EIM79348.1 - 0.00033 20.8 0.2 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 BID domain of Bartonella effector protein (Bep) DUF4061 PF13270.6 EIM79348.1 - 0.0011 19.2 0.1 3.1 8.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4061) Pox_F11 PF04943.12 EIM79348.1 - 0.0023 17.1 0.1 2.1 7.3 0.0 2.2 2 0 0 2 2 2 2 Poxvirus F11 protein RE_TdeIII PF09520.10 EIM79348.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII HSBP1 PF06825.12 EIM79348.1 - 0.02 14.7 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Retrotrans_gag PF03732.17 EIM79348.1 - 0.023 14.9 0.0 40 4.6 0.0 3.5 3 0 0 3 3 3 0 Retrotransposon gag protein STAT_alpha PF01017.20 EIM79348.1 - 0.025 14.5 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 STAT protein, all-alpha domain eIF3g PF12353.8 EIM79348.1 - 0.044 14.2 4.0 0.16 12.4 3.8 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Prefoldin_2 PF01920.20 EIM79348.1 - 0.15 12.0 0.3 29 4.7 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit Toprim PF01751.22 EIM79348.1 - 0.16 12.2 0.2 38 4.6 0.0 2.6 2 0 0 2 2 2 0 Toprim domain zf-CCHC_5 PF14787.6 EIM79348.1 - 0.17 11.6 1.4 0.4 10.4 1.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Snapin_Pallidin PF14712.6 EIM79348.1 - 0.18 12.3 0.4 33 5.0 0.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin DUF2968 PF11180.8 EIM79348.1 - 0.19 11.4 1.1 20 4.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF1664 PF07889.12 EIM79348.1 - 0.22 11.6 2.8 15 5.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SOG2 PF10428.9 EIM79350.1 - 0.084 12.1 8.5 0.089 12.0 8.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF515 PF04415.12 EIM79350.1 - 2.5 6.4 14.4 3.3 6.0 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Hamartin PF04388.12 EIM79350.1 - 7.5 5.1 8.7 8.9 4.8 8.7 1.1 1 0 0 1 1 1 0 Hamartin protein GMC_oxred_N PF00732.19 EIM79352.1 - 3.1e-60 204.1 0.0 3.9e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM79352.1 - 5.1e-32 111.4 0.0 2.5e-31 109.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM79352.1 - 6.1e-05 22.2 0.1 0.00043 19.5 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EIM79352.1 - 6.1e-05 23.2 0.2 0.00014 22.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM79352.1 - 0.00023 20.9 0.2 0.0035 17.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM79352.1 - 0.00097 18.3 0.6 0.0017 17.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM79352.1 - 0.0014 17.9 0.0 0.0039 16.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM79352.1 - 0.0091 14.7 0.1 0.028 13.1 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM79352.1 - 0.014 14.7 0.2 0.095 11.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM79352.1 - 0.1 11.8 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Phtf-FEM1B_bdg PF12129.8 EIM79353.1 - 8 6.3 6.6 20 5.0 1.1 2.3 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Pkinase PF00069.25 EIM79354.1 - 9.7e-47 159.5 0.0 1.2e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM79354.1 - 9.1e-26 90.7 0.0 5.1e-25 88.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM79354.1 - 4e-07 29.6 0.0 5.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM79354.1 - 0.0014 18.7 0.0 0.0041 17.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM79354.1 - 0.003 16.4 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EIM79354.1 - 0.017 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EIM79354.1 - 0.03 13.9 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ADH_N PF08240.12 EIM79355.1 - 3e-26 91.4 4.6 5.2e-26 90.7 4.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM79355.1 - 6.9e-17 61.7 0.0 1.2e-15 57.7 0.0 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIM79355.1 - 0.0036 16.6 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EIM79355.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_MLP1_2 PF07926.12 EIM79357.1 - 1.7e-26 92.8 24.0 1.7e-26 92.8 24.0 16.8 7 5 9 16 16 16 4 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EIM79357.1 - 0.03 14.8 0.6 0.012 16.1 12.3 17.9 4 3 13 17 17 17 0 Apg6 coiled-coil region Exog_C PF18026.1 EIM79357.1 - 3.2 7.9 7.0 9.6 6.4 1.1 3.3 1 1 1 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain ADH_N PF08240.12 EIM79359.1 - 6.9e-27 93.5 6.1 1.2e-26 92.7 6.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM79359.1 - 6.3e-20 71.5 0.0 2.3e-16 60.0 0.0 3.2 2 1 1 3 3 3 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIM79359.1 - 0.0025 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EIM79359.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Adeno_E3_CR2 PF02439.15 EIM79362.1 - 0.0056 16.4 2.1 0.0097 15.7 2.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EIM79362.1 - 0.049 13.0 0.3 0.096 12.1 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1921 PF09081.10 EIM79362.1 - 0.055 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) Syndecan PF01034.20 EIM79362.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Paralemmin PF03285.15 EIM79362.1 - 1.2 8.7 3.7 0.29 10.7 0.5 1.4 2 0 0 2 2 2 0 Paralemmin HECT PF00632.25 EIM79363.1 - 4.3e-94 315.5 0.0 5.7e-94 315.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EIM79363.1 - 0.0015 18.1 0.2 0.0015 18.1 0.2 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif Acid_PPase PF12689.7 EIM79364.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Acid Phosphatase p450 PF00067.22 EIM79365.1 - 1.7e-58 198.5 0.0 2.2e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SET PF00856.28 EIM79366.1 - 9.9e-12 45.6 0.1 5.9e-10 39.8 0.0 2.5 2 1 0 2 2 2 1 SET domain Glyco_hydro_18 PF00704.28 EIM79367.1 - 2.5e-56 191.7 1.4 3.9e-56 191.1 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 stn_TNFRSF12A PF12191.8 EIM79369.1 - 0.052 13.8 2.4 0.22 11.8 2.2 2.3 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Peptidase_A4 PF01828.17 EIM79371.1 - 2.5e-75 252.5 18.9 2.8e-75 252.4 18.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.17 EIM79372.1 - 6.4e-69 231.6 11.6 6.4e-69 231.6 11.6 1.8 2 0 0 2 2 2 1 Peptidase A4 family Abhydrolase_1 PF00561.20 EIM79373.1 - 7.6e-17 61.8 0.4 6.6e-16 58.7 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM79373.1 - 6.5e-09 35.4 0.0 1.8e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM79373.1 - 7.9e-09 36.4 0.0 1.1e-08 36.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EIM79373.1 - 0.00048 20.3 0.1 0.00086 19.5 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 EIM79373.1 - 0.007 16.0 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 EIM79373.1 - 0.0073 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 EIM79373.1 - 0.11 11.7 0.1 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Dimer_Tnp_hAT PF05699.14 EIM79378.1 - 1.6e-05 24.6 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Plavaka PF18759.1 EIM79381.1 - 1.4e-15 57.4 0.1 2.1e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 EIM79382.1 - 3.4e-69 233.5 0.2 3.8e-69 233.4 0.2 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 EIM79383.1 - 2.2e-11 43.6 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase SAT PF16073.5 EIM79384.1 - 2.8e-09 37.1 0.0 3.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis TipE PF16972.5 EIM79385.1 - 0.6 9.2 3.9 1.1 8.3 3.9 1.3 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE TFIIA PF03153.13 EIM79385.1 - 3.2 7.6 31.0 9.1 6.1 26.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Gly-zipper_YMGG PF13441.6 EIM79387.1 - 0.056 13.2 11.0 0.69 9.7 1.8 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EIM79387.1 - 0.67 10.0 14.0 2.8 8.0 3.9 2.4 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 EIM79387.1 - 3.7 7.4 19.5 2.7 7.8 5.6 2.5 2 0 0 2 2 2 0 Glycine-zipper domain Bacteriocin_IIc PF10439.9 EIM79387.1 - 4.1 7.6 8.8 1.5 9.0 1.4 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Peptidase_A4 PF01828.17 EIM79390.1 - 6.3e-71 238.2 12.7 7.1e-71 238.0 12.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family AA_permease PF00324.21 EIM79391.1 - 0.046 12.3 1.4 0.046 12.3 0.2 1.7 2 1 0 2 2 2 0 Amino acid permease WD40 PF00400.32 EIM79392.1 - 2.9e-83 271.6 21.9 8.6e-10 39.1 0.0 8.7 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79392.1 - 1.1e-26 92.9 2.8 0.032 14.5 0.0 8.0 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EIM79392.1 - 9.3e-08 32.2 0.1 3.3e-07 30.4 0.1 1.8 1 1 0 1 1 1 1 NACHT domain eIF2A PF08662.11 EIM79392.1 - 3.5e-07 30.3 0.0 0.023 14.6 0.0 3.9 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 EIM79392.1 - 1.8e-06 27.9 0.3 32 4.6 0.0 7.4 7 1 1 8 8 8 0 Ciliary BBSome complex subunit 2, middle region AAA_16 PF13191.6 EIM79392.1 - 3.4e-06 27.6 0.0 1.1e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain WD40_like PF17005.5 EIM79392.1 - 7.7e-05 22.2 0.0 24 4.1 0.0 5.8 4 3 1 6 6 6 0 WD40-like domain PQQ_3 PF13570.6 EIM79392.1 - 0.002 18.6 0.0 1.2e+02 3.3 0.0 6.3 7 1 1 8 8 8 0 PQQ-like domain AAA_22 PF13401.6 EIM79392.1 - 0.0069 16.7 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Oxidored-like PF09791.9 EIM79392.1 - 0.11 12.2 0.4 0.23 11.2 0.4 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal Y1_Tnp PF01797.16 EIM79392.1 - 0.15 12.1 0.2 0.49 10.5 0.1 1.9 2 0 0 2 2 2 0 Transposase IS200 like WD40 PF00400.32 EIM79393.1 - 4.5e-33 112.7 7.0 1.4e-09 38.4 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79393.1 - 2.1e-11 43.9 0.0 0.17 12.2 0.0 4.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MerR_1 PF13411.6 EIM79393.1 - 0.0005 20.1 0.0 11 6.2 0.0 3.6 4 0 0 4 4 4 2 MerR HTH family regulatory protein BBS2_Mid PF14783.6 EIM79393.1 - 0.0016 18.4 0.0 27 4.9 0.0 3.9 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EIM79393.1 - 0.0098 15.2 0.0 6.2 6.0 0.0 3.0 2 1 2 4 4 4 2 WD40-like domain MerR PF00376.23 EIM79393.1 - 0.03 14.1 0.0 9.9 6.0 0.0 3.1 3 0 0 3 3 3 0 MerR family regulatory protein PD40 PF07676.12 EIM79393.1 - 0.033 14.1 0.0 67 3.6 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 EIM79393.1 - 0.062 11.6 0.0 15 3.7 0.0 2.9 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-MYND PF01753.18 EIM79394.1 - 1.1e-09 38.2 13.0 1.1e-09 38.2 13.0 2.5 2 1 1 3 3 3 1 MYND finger AA_permease_2 PF13520.6 EIM79395.1 - 1.6e-62 211.7 48.5 1.9e-62 211.5 48.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM79395.1 - 8.6e-15 54.3 38.2 8.6e-15 54.3 38.2 1.3 1 1 0 1 1 1 1 Amino acid permease MAP65_ASE1 PF03999.12 EIM79397.1 - 0.2 10.4 1.9 0.41 9.3 1.9 1.6 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) zf-MYND PF01753.18 EIM79399.1 - 3.9e-10 39.7 16.1 2.1e-09 37.3 16.1 2.2 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM79399.1 - 1.7 9.0 11.6 3.4 8.1 11.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Elf1 PF05129.13 EIM79400.1 - 0.05 13.6 0.6 0.12 12.4 0.6 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.12 EIM79400.1 - 0.077 12.5 0.9 0.17 11.4 0.9 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 EIM79400.1 - 0.59 10.5 1.8 9.6 6.7 0.6 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar MFS_1 PF07690.16 EIM79402.1 - 1.8e-23 83.0 30.3 2e-16 59.9 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79402.1 - 1.8e-14 53.4 16.4 1.9e-13 50.1 16.1 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Myc_target_1 PF15179.6 EIM79402.1 - 0.083 12.8 0.5 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 Myc target protein 1 Phage-MuB_C PF09077.11 EIM79402.1 - 0.096 12.6 0.0 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Mu B transposition protein, C terminal ICMT PF04140.14 EIM79407.1 - 5.7e-12 45.9 0.1 1.2e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM79407.1 - 1.8e-11 44.3 3.0 3.7e-11 43.4 1.1 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM79407.1 - 4.1e-06 25.8 0.1 1.3e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Abhydrolase_3 PF07859.13 EIM79408.1 - 3.1e-12 46.8 0.0 8.5e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM79408.1 - 5.5e-10 39.1 0.0 2.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EIM79408.1 - 0.00046 19.8 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EIM79408.1 - 0.00057 20.5 2.4 0.0018 18.9 2.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 EIM79408.1 - 0.00061 18.8 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_1 PF00561.20 EIM79408.1 - 0.0075 15.9 0.1 0.15 11.7 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EIM79408.1 - 0.023 13.4 0.0 0.055 12.1 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EIM79408.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zf-MYND PF01753.18 EIM79409.1 - 1.4e-08 34.7 15.1 1.4e-08 34.7 15.1 2.2 2 0 0 2 2 2 1 MYND finger DUF2335 PF10097.9 EIM79409.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) zf-C6H2 PF15801.5 EIM79409.1 - 0.18 12.1 5.7 0.48 10.8 5.7 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Tnp_zf-ribbon_2 PF13842.6 EIM79409.1 - 4.8 8.1 8.8 10 7.0 8.8 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Carboxyl_trans PF01039.22 EIM79410.1 - 0.019 13.6 0.0 0.023 13.3 0.0 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain Leader_Erm PF08253.11 EIM79411.1 - 1.1 9.7 3.9 0.57 10.6 0.3 2.3 2 0 0 2 2 2 0 Erm Leader peptide Aminotran_1_2 PF00155.21 EIM79412.1 - 3.9e-41 141.4 0.0 4.4e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIM79412.1 - 6.8e-06 25.6 0.2 1e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EIM79412.1 - 2.2e-05 23.2 0.0 3.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EIM79412.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V FAD-oxidase_C PF02913.19 EIM79413.1 - 1e-53 182.6 0.1 1.6e-53 181.9 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EIM79413.1 - 4.7e-30 104.1 0.0 8.9e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain VirB8 PF04335.13 EIM79414.1 - 0.055 13.3 2.2 1.9 8.3 0.4 2.2 2 0 0 2 2 2 0 VirB8 protein Orthoreo_P17 PF07272.11 EIM79415.1 - 0.15 12.1 0.4 0.81 9.7 0.1 2.3 2 0 0 2 2 2 0 Orthoreovirus P17 protein DUF3392 PF11872.8 EIM79415.1 - 0.9 9.8 4.2 0.21 11.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) PQ-loop PF04193.14 EIM79416.1 - 2.7e-18 65.5 3.4 1.7e-09 37.3 0.1 3.7 3 0 0 3 3 3 3 PQ loop repeat Ank_4 PF13637.6 EIM79418.1 - 4.3e-15 55.9 0.0 2.1e-08 34.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM79418.1 - 1.7e-10 41.4 0.0 2.4e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIM79418.1 - 8.4e-09 35.5 0.1 0.0044 17.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EIM79418.1 - 4.8e-08 32.7 0.0 0.00081 19.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EIM79418.1 - 0.00082 19.6 0.0 0.27 11.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 EIM79418.1 - 0.023 15.2 0.7 0.21 12.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ank_4 PF13637.6 EIM79419.1 - 1.9e-11 44.3 0.2 2.3e-11 44.0 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM79419.1 - 3.2e-09 37.2 0.3 8.9e-09 35.8 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIM79419.1 - 5.3e-08 32.5 0.2 0.0042 17.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EIM79419.1 - 7.6e-08 32.5 0.5 0.0049 17.3 0.1 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EIM79419.1 - 3.3e-07 30.4 0.2 0.0023 18.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIM79420.1 - 9.9e-23 80.2 2.7 1.3e-06 28.8 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM79420.1 - 5.6e-17 62.1 3.4 7.4e-11 42.5 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EIM79420.1 - 3.1e-12 46.3 3.2 0.023 15.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EIM79420.1 - 2.3e-10 39.8 0.1 0.057 14.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EIM79420.1 - 3.1e-07 30.5 0.2 0.0019 18.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF3396 PF11876.8 EIM79420.1 - 0.25 10.8 1.2 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3396) Big_7 PF17957.1 EIM79421.1 - 0.023 15.5 1.3 0.039 14.7 1.3 1.6 1 1 0 1 1 1 0 Bacterial Ig domain F-box-like PF12937.7 EIM79422.1 - 8.5e-08 32.0 1.2 3.5e-07 30.0 1.2 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM79423.1 - 1.1e-05 25.2 0.5 3.9e-05 23.5 0.2 2.0 2 0 0 2 2 2 1 F-box-like DUF3088 PF11287.8 EIM79423.1 - 0.16 11.8 0.1 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) Helitron_like_N PF14214.6 EIM79425.1 - 2.6e-08 34.3 0.0 5.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus GSG-1 PF07803.11 EIM79425.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 GSG1-like protein DUF753 PF05444.12 EIM79425.1 - 1.6 8.7 7.4 0.37 10.8 4.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF753) PIF1 PF05970.14 EIM79426.1 - 0.11 11.6 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 PIF1-like helicase SH3_13 PF18335.1 EIM79426.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 EIM79427.1 - 0.014 15.2 0.0 0.047 13.5 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Phytase PF02333.15 EIM79428.1 - 0.044 12.7 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Phytase KH_5 PF13184.6 EIM79428.1 - 0.14 12.2 0.3 0.81 9.8 0.0 2.3 3 0 0 3 3 3 0 NusA-like KH domain CHAT PF12770.7 EIM79429.1 - 5.4e-37 127.8 0.0 9.2e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM79429.1 - 1e-08 34.7 30.0 0.0072 16.2 0.0 11.2 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM79429.1 - 1.7e-08 34.0 1.5 0.052 13.2 0.0 6.1 5 1 0 5 5 5 2 TPR repeat TPR_2 PF07719.17 EIM79429.1 - 1.5e-06 27.8 3.7 7.9 6.9 0.0 8.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM79429.1 - 3.3e-06 26.9 3.6 12 6.4 0.0 8.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM79429.1 - 6.1e-05 23.5 12.6 5.3 8.1 0.0 7.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM79429.1 - 0.00044 20.0 1.8 77 3.4 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIM79429.1 - 0.0012 19.4 3.6 4.6 8.0 0.0 4.9 3 1 3 6 6 6 2 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EIM79429.1 - 0.0087 16.1 0.1 12 6.1 0.0 4.9 7 0 0 7 7 7 1 Exonuclease VII small subunit TPR_7 PF13176.6 EIM79429.1 - 0.17 11.9 8.2 15 5.9 0.0 7.2 9 1 0 9 9 9 0 Tetratricopeptide repeat ubiquitin PF00240.23 EIM79430.1 - 8.5e-18 63.9 0.3 9.5e-18 63.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EIM79430.1 - 5e-06 26.3 0.7 7.2e-06 25.8 0.7 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EIM79430.1 - 0.0011 19.5 0.0 0.0013 19.3 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 EIM79430.1 - 0.0068 16.8 0.3 0.035 14.5 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain BrnT_toxin PF04365.13 EIM79430.1 - 0.15 12.4 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system PHD PF00628.29 EIM79431.1 - 0.6 10.0 8.8 0.097 12.6 4.1 2.3 2 0 0 2 2 2 0 PHD-finger eIF3_N PF09440.10 EIM79432.1 - 3.3e-48 163.5 4.4 9.8e-48 162.0 4.3 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EIM79432.1 - 1.8e-09 38.0 0.6 8.2e-09 35.9 0.1 2.3 2 1 1 3 3 3 1 PCI domain Dor1 PF04124.12 EIM79434.1 - 8.3e-12 44.4 0.0 1.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Dor1-like family KDZ PF18758.1 EIM79436.1 - 6.2e-57 192.8 0.0 1.6e-56 191.4 0.0 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM79436.1 - 6.2e-44 148.5 1.1 1.4e-43 147.5 0.2 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM79436.1 - 1.9e-05 24.8 0.4 0.00018 21.6 0.1 2.5 3 0 0 3 3 3 1 CxC1 like cysteine cluster associated with KDZ transposases AD PF09793.9 EIM79436.1 - 4.3 7.6 4.6 2.9 8.1 0.2 2.8 3 0 0 3 3 3 0 Anticodon-binding domain 2OG-FeII_Oxy_3 PF13640.6 EIM79437.1 - 0.011 16.6 0.0 0.028 15.3 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Asp_protease_2 PF13650.6 EIM79438.1 - 8.3e-08 32.8 0.0 2.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EIM79438.1 - 3.8e-05 24.2 0.0 8.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease K_trans PF02705.16 EIM79439.1 - 5.2e-50 170.5 2.6 5.2e-50 170.5 2.6 1.7 2 0 0 2 2 2 1 K+ potassium transporter APH PF01636.23 EIM79440.1 - 1.1e-16 61.6 0.0 1.4e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM79440.1 - 2.6e-05 23.9 0.0 3.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EIM79440.1 - 0.0064 15.4 0.0 0.028 13.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 EIM79440.1 - 0.047 13.1 0.0 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 EIM79440.1 - 0.11 11.9 0.0 16 4.8 0.0 2.4 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family K_trans PF02705.16 EIM79443.1 - 4.4e-176 586.5 11.2 5.8e-176 586.1 11.2 1.1 1 0 0 1 1 1 1 K+ potassium transporter RhoGAP PF00620.27 EIM79444.1 - 4.5e-15 55.8 0.0 7.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SHE3 PF17078.5 EIM79445.1 - 0.0068 16.2 2.7 0.0068 16.2 2.7 4.7 2 2 2 5 5 5 2 SWI5-dependent HO expression protein 3 HALZ PF02183.18 EIM79445.1 - 0.13 12.5 30.0 1.4 9.2 0.5 7.6 6 1 1 7 7 7 0 Homeobox associated leucine zipper TLE_N PF03920.15 EIM79445.1 - 3.7 7.6 14.0 5.9 7.0 0.1 4.0 4 1 0 4 4 4 0 Groucho/TLE N-terminal Q-rich domain HAP1_N PF04849.13 EIM79446.1 - 0.029 13.6 11.4 0.046 12.9 11.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HAUS4 PF14735.6 EIM79446.1 - 0.29 10.8 8.0 0.45 10.2 8.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 OmpH PF03938.14 EIM79446.1 - 3.4 8.0 8.2 6.3 7.1 8.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM76 PF16046.5 EIM79446.1 - 5.6 6.2 6.3 9.8 5.4 6.3 1.3 1 0 0 1 1 1 0 FAM76 protein LCD1 PF09798.9 EIM79446.1 - 8 4.8 9.0 11 4.4 9.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Miga PF10265.9 EIM79447.1 - 1.3 7.9 3.4 2.2 7.2 3.4 1.2 1 0 0 1 1 1 0 Mitoguardin APH PF01636.23 EIM79448.1 - 2.8e-12 47.1 0.0 6.1e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM79448.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA PF00004.29 EIM79449.1 - 1.9e-18 67.1 0.0 3.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM79449.1 - 2.6e-05 24.5 0.6 0.0011 19.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EIM79449.1 - 2.7e-05 24.6 3.0 0.00034 21.0 1.4 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EIM79449.1 - 0.00091 19.2 0.1 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EIM79449.1 - 0.0021 17.8 0.2 0.0056 16.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM79449.1 - 0.0075 16.1 0.9 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EIM79449.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIM79449.1 - 0.036 14.5 0.1 0.57 10.6 0.0 2.8 3 0 0 3 3 3 0 RNA helicase RuvB_N PF05496.12 EIM79449.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zot PF05707.12 EIM79449.1 - 0.061 13.0 0.0 2.7 7.6 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_28 PF13521.6 EIM79449.1 - 0.071 13.4 0.1 0.2 11.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EIM79449.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 EIM79449.1 - 0.084 13.2 0.2 0.27 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.8 EIM79449.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DsrH PF04077.12 EIM79449.1 - 0.12 12.5 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 DsrH like protein AAA_18 PF13238.6 EIM79449.1 - 0.14 12.7 0.0 0.45 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EIM79449.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EIM79449.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EIM79449.1 - 0.2 11.0 0.2 0.53 9.6 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI BTB PF00651.31 EIM79450.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain zf-MYND PF01753.18 EIM79451.1 - 2.9e-09 36.9 11.8 6.4e-09 35.7 11.8 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM79451.1 - 0.0085 16.4 6.8 0.016 15.5 6.8 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding TSP_3 PF02412.18 EIM79452.1 - 0.0013 18.3 9.1 0.0023 17.6 0.4 2.7 3 0 0 3 3 3 2 Thrombospondin type 3 repeat Sina PF03145.16 EIM79452.1 - 0.99 9.3 6.6 3.6 7.5 0.7 2.3 1 1 0 2 2 2 0 Seven in absentia protein family Aminotran_5 PF00266.19 EIM79453.1 - 1.9e-41 142.3 0.0 5.2e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V CFEM PF05730.11 EIM79454.1 - 1.4e-10 41.1 9.5 1.9e-10 40.7 9.5 1.2 1 0 0 1 1 1 1 CFEM domain Baculo_PEP_C PF04513.12 EIM79455.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 EIM79455.1 - 0.45 9.0 10.3 0.58 8.6 10.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4805 PF16063.5 EIM79455.1 - 1.1 8.6 4.5 1.5 8.0 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Hamartin PF04388.12 EIM79455.1 - 4.5 5.8 5.7 5.1 5.6 5.7 1.0 1 0 0 1 1 1 0 Hamartin protein DNA_pol_phi PF04931.13 EIM79455.1 - 9.4 4.2 12.8 12 3.8 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi AAA PF00004.29 EIM79456.1 - 1.2e-17 64.5 0.0 2.2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM79456.1 - 1.9e-06 28.4 0.5 7.6e-06 26.4 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM79456.1 - 3e-05 24.3 1.6 0.0018 18.5 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EIM79456.1 - 0.00056 19.9 0.2 0.0031 17.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EIM79456.1 - 0.0018 18.4 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM79456.1 - 0.0033 17.2 0.2 0.01 15.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM79456.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EIM79456.1 - 0.01 15.9 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EIM79456.1 - 0.019 15.5 0.0 0.068 13.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 EIM79456.1 - 0.035 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EIM79456.1 - 0.037 14.4 0.1 0.13 12.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 EIM79456.1 - 0.056 13.7 0.1 0.23 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EIM79456.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EIM79456.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EIM79456.1 - 0.16 11.3 0.2 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI GMC_oxred_N PF00732.19 EIM79458.1 - 2.9e-66 223.8 0.0 3.6e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM79458.1 - 1.2e-37 129.6 0.0 3e-37 128.4 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM79458.1 - 5.6e-05 22.4 0.0 8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EIM79458.1 - 5.6e-05 22.9 0.4 0.003 17.2 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM79458.1 - 7.4e-05 22.9 0.5 0.00023 21.3 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM79458.1 - 0.0001 21.6 0.0 0.00084 18.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM79458.1 - 0.0002 20.6 0.3 0.01 15.0 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIM79458.1 - 0.019 13.7 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EIM79458.1 - 0.058 12.6 0.1 0.13 11.4 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EIM79458.1 - 0.065 13.8 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM79458.1 - 0.073 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 EIM79458.1 - 0.16 11.6 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EIM79458.1 - 0.21 10.4 0.2 0.3 9.9 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MPS-4 PF17523.2 EIM79459.1 - 6 7.1 6.0 0.9 9.7 0.2 2.6 2 1 1 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Coprogen_oxidas PF01218.18 EIM79460.1 - 1.1e-85 286.9 0.0 2e-85 286.1 0.0 1.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase GMC_oxred_N PF00732.19 EIM79461.1 - 2e-68 231.0 0.0 2.5e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM79461.1 - 1.8e-36 125.8 0.0 3.1e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM79461.1 - 8.9e-06 25.0 0.2 0.01 15.0 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EIM79461.1 - 7.1e-05 22.0 0.1 0.0001 21.5 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EIM79461.1 - 8.1e-05 22.8 0.5 0.00023 21.3 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM79461.1 - 0.00027 20.3 0.0 0.00062 19.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM79461.1 - 0.00039 20.1 0.6 0.0035 17.0 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM79461.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EIM79461.1 - 0.07 13.7 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM79461.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EIM79461.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EIM79461.1 - 0.22 10.3 0.2 0.3 9.9 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 EIM79461.1 - 0.22 10.7 0.1 0.52 9.5 0.1 1.6 2 0 0 2 2 2 0 Thi4 family KASH_CCD PF14662.6 EIM79462.1 - 0.019 14.8 20.0 1.2 8.9 4.1 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF2235 PF09994.9 EIM79463.1 - 1e-66 225.2 0.0 1.5e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Dimer_Tnp_hAT PF05699.14 EIM79464.1 - 4.6e-12 45.6 0.0 6.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Androgen_recep PF02166.16 EIM79464.1 - 0.042 12.7 1.8 0.061 12.2 1.8 1.2 1 0 0 1 1 1 0 Androgen receptor CFEM PF05730.11 EIM79465.1 - 5.6e-09 36.0 17.1 1.1e-08 35.0 17.1 1.5 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 EIM79465.1 - 1.9 7.0 7.8 2 6.9 7.8 1.1 1 0 0 1 1 1 0 Macoilin family CFEM PF05730.11 EIM79466.1 - 1.4e-11 44.3 13.3 3e-11 43.2 13.3 1.6 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 EIM79466.1 - 9.3 4.7 10.4 11 4.5 10.4 1.2 1 0 0 1 1 1 0 Macoilin family F-box-like PF12937.7 EIM79467.1 - 5.4e-07 29.4 6.1 1.7e-06 27.8 6.1 1.9 1 0 0 1 1 1 1 F-box-like TMEM51 PF15345.6 EIM79468.1 - 0.0074 16.2 0.3 0.013 15.3 0.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Amnionless PF14828.6 EIM79468.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Amnionless DUF2576 PF10845.8 EIM79468.1 - 0.016 14.8 0.7 0.58 9.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) TMEM154 PF15102.6 EIM79468.1 - 0.28 11.1 3.5 0.77 9.7 3.3 1.9 1 1 0 1 1 1 0 TMEM154 protein family SecG PF03840.14 EIM79468.1 - 0.33 11.0 2.0 0.84 9.8 2.0 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Plasmodium_Vir PF05795.11 EIM79468.1 - 2.5 7.4 7.8 2 7.8 5.4 2.0 2 1 0 2 2 2 0 Plasmodium vivax Vir protein iPGM_N PF06415.13 EIM79471.1 - 1.9e-77 259.6 0.1 2.9e-77 258.9 0.1 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EIM79471.1 - 4.6e-70 235.8 0.0 2e-69 233.7 0.0 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EIM79471.1 - 3.3e-05 23.4 0.1 0.00051 19.5 0.1 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EIM79471.1 - 0.00033 20.4 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 EIM79471.1 - 0.13 12.4 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 PglZ domain RicinB_lectin_2 PF14200.6 EIM79473.1 - 5.7e-09 36.6 13.8 0.00029 21.5 0.2 3.7 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Botulinum_HA-17 PF05588.11 EIM79473.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Clostridium botulinum HA-17 domain Tub PF01167.18 EIM79473.1 - 0.023 14.5 0.4 0.023 14.5 0.4 1.6 2 0 0 2 2 2 0 Tub family CDtoxinA PF03498.14 EIM79473.1 - 0.053 13.1 3.7 0.39 10.3 0.2 2.8 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain FlgT_C PF16538.5 EIM79473.1 - 0.17 12.5 0.7 12 6.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain CBM_2 PF00553.19 EIM79473.1 - 0.23 11.8 8.6 1.6 9.1 1.0 2.6 2 1 0 2 2 2 0 Cellulose binding domain Inhibitor_I66 PF16850.5 EIM79473.1 - 0.45 10.4 7.0 1.7 8.5 0.2 3.3 1 1 3 4 4 4 0 Peptidase inhibitor I66 p450 PF00067.22 EIM79474.1 - 3.4e-60 204.1 0.0 3.8e-33 114.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CHAT PF12770.7 EIM79475.1 - 8e-26 91.1 0.3 2e-25 89.8 0.1 1.7 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 EIM79475.1 - 8.2e-06 25.5 5.9 0.0099 15.7 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM79475.1 - 0.0019 18.2 1.5 28 5.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 EIM79475.1 - 0.098 13.0 0.1 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_12 PF13424.6 EIM79475.1 - 0.11 12.8 11.3 1.5 9.2 0.1 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat Med14 PF08638.11 EIM79475.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit MED14 TPR_7 PF13176.6 EIM79475.1 - 0.15 12.2 5.0 7.7 6.8 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Vac17 PF17321.2 EIM79475.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Vacuole-related protein 17 TPR_1 PF00515.28 EIM79475.1 - 0.76 9.7 4.6 50 3.9 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 EIM79476.1 - 3.6e-07 29.9 0.0 5.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2635 PF10948.8 EIM79476.1 - 0.02 14.6 0.0 0.068 12.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Kazal_3 PF18434.1 EIM79477.1 - 0.67 9.8 5.3 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Lactamase_B PF00753.27 EIM79480.1 - 5.9e-07 29.7 0.2 1.8e-06 28.1 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIM79480.1 - 0.017 14.7 0.2 0.034 13.6 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Glyco_transf_5 PF08323.11 EIM79480.1 - 0.32 10.6 1.4 2.7 7.6 0.0 2.3 3 0 0 3 3 3 0 Starch synthase catalytic domain F-box-like PF12937.7 EIM79481.1 - 0.00054 19.8 0.4 0.0019 18.1 0.4 2.0 1 0 0 1 1 1 1 F-box-like DUF1479 PF07350.12 EIM79482.1 - 8.3e-66 222.5 0.0 1e-65 222.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Goodbye PF17109.5 EIM79483.1 - 5.2e-07 30.1 0.1 1.5e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EIM79483.1 - 6.8e-06 26.1 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain APH PF01636.23 EIM79483.1 - 1e-05 25.6 0.6 0.0004 20.4 0.5 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM79483.1 - 3.2e-05 23.4 0.0 6.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain AAA_22 PF13401.6 EIM79483.1 - 0.00057 20.2 0.0 0.0019 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain UCR_14kD PF02271.16 EIM79483.1 - 0.061 13.3 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit ATPase PF06745.13 EIM79483.1 - 0.11 11.9 0.0 14 5.0 0.0 2.4 2 0 0 2 2 2 0 KaiC Peptidase_C14 PF00656.22 EIM79484.1 - 1.7e-22 80.6 0.0 3.5e-22 79.6 0.0 1.4 2 0 0 2 2 2 1 Caspase domain CHAT PF12770.7 EIM79485.1 - 1.7e-36 126.1 0.1 4.8e-36 124.6 0.1 1.8 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM79485.1 - 7.7e-07 28.8 4.6 1.2 9.1 0.0 7.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM79485.1 - 0.0048 17.0 0.2 12 6.4 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Pkinase PF00069.25 EIM79486.1 - 5.9e-23 81.6 0.0 1.2e-22 80.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM79486.1 - 1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM79486.1 - 1e-06 28.9 0.2 0.0042 17.0 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EIM79486.1 - 0.021 14.0 0.0 0.057 12.6 0.0 1.7 1 1 1 2 2 2 0 Fructosamine kinase Pkinase_fungal PF17667.1 EIM79486.1 - 0.032 13.0 0.1 0.048 12.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EIM79486.1 - 0.073 12.4 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like CHAT PF12770.7 EIM79489.1 - 1e-11 44.8 0.1 1.3e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 CHAT domain Spo7_2_N PF15407.6 EIM79489.1 - 0.024 14.2 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 CDC45 PF02724.14 EIM79494.1 - 0.006 14.9 3.2 0.0069 14.7 3.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EIM79494.1 - 0.032 12.5 7.6 0.043 12.1 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EIM79494.1 - 0.033 13.6 8.0 0.055 12.9 6.1 1.9 2 0 0 2 2 2 0 SDA1 PHM7_ext PF12621.8 EIM79494.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter BUD22 PF09073.10 EIM79494.1 - 0.46 9.8 8.8 0.79 9.0 8.8 1.4 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 EIM79494.1 - 3.4 7.0 12.9 4.1 6.7 10.7 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT YL1 PF05764.13 EIM79495.1 - 0.02 15.1 1.9 0.02 15.1 1.9 1.9 2 0 0 2 2 2 0 YL1 nuclear protein PCIF1_WW PF12237.8 EIM79495.1 - 0.13 11.9 0.6 7.1 6.2 0.0 2.3 1 1 1 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain ORC6 PF05460.13 EIM79495.1 - 0.9 8.7 6.7 1.5 8.0 6.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CAP_N PF01213.19 EIM79495.1 - 1.1 8.7 7.9 2.7 7.4 7.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Soyouz_module PF14313.6 EIM79495.1 - 1.5 8.7 4.4 0.51 10.1 0.2 2.3 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Cwf_Cwc_15 PF04889.12 EIM79495.1 - 2 8.1 7.9 2.6 7.7 5.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Plavaka PF18759.1 EIM79496.1 - 1.7e-106 356.2 0.0 2.3e-106 355.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Milton PF12448.8 EIM79496.1 - 0.063 13.4 4.2 0.12 12.5 4.2 1.4 1 0 0 1 1 1 0 Kinesin associated protein Sporozoite_P67 PF05642.11 EIM79496.1 - 0.18 9.9 3.9 0.25 9.4 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.12 EIM79498.1 - 0.032 14.1 8.7 0.058 13.2 8.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EIM79498.1 - 0.13 12.4 0.6 0.23 11.6 0.6 1.3 1 0 0 1 1 1 0 DDHD domain PPL5 PF18168.1 EIM79498.1 - 0.21 10.8 2.5 0.37 10.0 2.5 1.3 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_Rpc4 PF05132.14 EIM79498.1 - 0.66 10.4 7.6 1.4 9.4 7.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 EIM79498.1 - 0.72 10.1 12.6 1.6 9.0 12.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CLN3 PF02487.17 EIM79498.1 - 1 8.3 2.6 1.8 7.5 2.6 1.3 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 EIM79498.1 - 1.3 8.4 9.5 2.2 7.7 9.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 EIM79498.1 - 1.7 7.3 11.0 2.8 6.6 11.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EIM79498.1 - 4.2 6.0 8.8 7.7 5.2 8.8 1.3 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EIM79498.1 - 5.1 6.8 10.8 8.8 6.0 10.8 1.3 1 0 0 1 1 1 0 Connexin G0-G1_switch_2 PF15103.6 EIM79498.1 - 6.6 7.2 9.0 16 6.0 9.0 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 Caldesmon PF02029.15 EIM79498.1 - 7.5 5.2 26.4 12 4.5 26.4 1.2 1 0 0 1 1 1 0 Caldesmon Serglycin PF04360.12 EIM79499.1 - 1.1 9.2 9.7 0.22 11.5 4.2 2.5 3 0 0 3 3 3 0 Serglycin NAD_binding_8 PF13450.6 EIM79500.1 - 8.4e-10 38.7 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIM79500.1 - 2.2e-08 33.8 0.0 7.3e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EIM79500.1 - 1.1e-05 24.9 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM79500.1 - 3.2e-05 23.3 0.0 6.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM79500.1 - 0.00013 21.3 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EIM79500.1 - 0.0002 21.1 0.0 0.00049 19.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM79500.1 - 0.00032 19.5 0.0 0.00047 19.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM79500.1 - 0.0012 18.1 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM79500.1 - 0.009 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EIM79500.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM79500.1 - 0.012 15.7 0.2 0.27 11.2 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EIM79500.1 - 0.013 16.1 0.0 0.059 13.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM79500.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein zf-MYND PF01753.18 EIM79501.1 - 4.7e-07 29.8 17.5 1e-06 28.7 17.5 1.5 1 0 0 1 1 1 1 MYND finger DUF2070 PF09843.9 EIM79502.1 - 4.5 5.4 8.1 9.4 4.4 8.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) FtsL PF04999.13 EIM79502.1 - 4.8 7.3 6.3 3.1 7.9 0.1 3.0 2 1 1 3 3 3 0 Cell division protein FtsL YiaAB PF05360.14 EIM79502.1 - 7.4 6.9 13.7 9.4 6.6 0.2 3.5 3 0 0 3 3 3 0 yiaA/B two helix domain WD40 PF00400.32 EIM79503.1 - 8.6e-114 368.2 69.2 6e-10 39.6 0.6 15.3 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79503.1 - 3.4e-44 149.0 20.4 0.00051 20.3 0.0 14.2 1 1 13 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM79503.1 - 2e-23 83.3 3.6 1.5e-05 24.9 0.0 6.1 1 1 5 6 6 6 6 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EIM79503.1 - 1.6e-18 66.8 13.9 0.26 10.2 0.0 12.6 1 1 13 14 14 14 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM79503.1 - 2.8e-18 66.3 2.8 0.04 13.3 0.0 8.3 4 3 5 9 9 9 7 WD40-like domain Cytochrom_D1 PF02239.16 EIM79503.1 - 1.3e-14 53.5 19.7 0.0007 18.2 0.2 6.3 1 1 5 7 7 7 5 Cytochrome D1 heme domain NACHT PF05729.12 EIM79503.1 - 1.8e-07 31.2 0.0 9.5e-07 28.9 0.0 2.2 2 1 0 2 2 2 1 NACHT domain Frtz PF11768.8 EIM79503.1 - 2.3e-06 26.3 0.0 1.4 7.2 0.0 4.9 4 2 1 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 EIM79503.1 - 1.5e-05 25.5 0.0 7e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 EIM79503.1 - 7.5e-05 22.5 0.0 1e+02 3.1 0.0 7.9 9 0 0 9 9 8 0 PQQ enzyme repeat Coatomer_WDAD PF04053.14 EIM79503.1 - 0.00011 21.4 3.5 0.0011 18.1 0.1 3.2 2 2 2 4 4 4 2 Coatomer WD associated region CNH PF00780.22 EIM79503.1 - 0.00013 21.7 1.3 7.7 6.0 0.0 7.1 8 1 2 10 10 10 1 CNH domain NB-ARC PF00931.22 EIM79503.1 - 0.0038 16.4 0.0 0.024 13.8 0.0 2.3 3 0 0 3 3 3 1 NB-ARC domain AAA PF00004.29 EIM79503.1 - 0.014 15.8 0.0 0.059 13.8 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1931 PF09123.11 EIM79503.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) AAA_18 PF13238.6 EIM79503.1 - 0.067 13.7 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EIM79503.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.15 EIM79503.1 - 0.13 12.1 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 EIM79503.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain YchF-GTPase_C PF06071.13 EIM79503.1 - 0.16 12.2 3.3 19 5.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF933) AAA_29 PF13555.6 EIM79503.1 - 0.17 11.6 0.2 3 7.6 0.1 3.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain PD40 PF07676.12 EIM79503.1 - 0.55 10.2 18.2 1e+02 3.0 0.0 9.3 13 0 0 13 13 10 0 WD40-like Beta Propeller Repeat G-alpha PF00503.20 EIM79504.1 - 1.1e-112 376.8 0.2 1.2e-112 376.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM79504.1 - 8.5e-16 57.9 0.6 2.5e-09 36.9 0.1 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIM79504.1 - 0.00045 19.6 0.1 0.87 8.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EIM79504.1 - 0.0041 17.3 0.1 0.3 11.3 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EIM79504.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arylsulfotran_2 PF14269.6 EIM79505.1 - 2.9e-57 194.3 11.1 2.9e-57 194.3 11.1 1.5 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EIM79505.1 - 1.7e-18 66.7 11.8 2e-17 63.2 11.8 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) EphA2_TM PF14575.6 EIM79506.1 - 0.038 14.9 0.0 0.067 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IPTL-CTERM PF18203.1 EIM79506.1 - 0.39 10.7 1.6 0.77 9.7 1.6 1.5 1 0 0 1 1 1 0 IPTL-CTERM motif p450 PF00067.22 EIM79507.1 - 3.5e-61 207.4 0.0 1.8e-32 112.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EIM79508.1 - 1.7e-44 152.3 0.0 2.2e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Importin_rep_4 PF18808.1 EIM79509.1 - 7.5e-18 64.6 0.3 3.5e-17 62.5 0.0 2.4 3 0 0 3 3 2 1 Importin repeat HEAT PF02985.22 EIM79509.1 - 2.9e-16 58.2 5.6 2.9e-06 27.1 0.1 8.7 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 EIM79509.1 - 6.1e-16 58.5 7.2 5.1e-06 26.9 0.0 7.2 6 1 1 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 EIM79509.1 - 7.7e-09 35.8 5.8 0.0029 17.9 0.1 6.1 5 2 3 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EIM79509.1 - 9.3e-09 35.8 0.0 0.00012 22.6 0.0 3.6 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EIM79509.1 - 2.5e-05 24.4 0.5 0.029 14.4 0.0 4.1 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EIM79509.1 - 0.00012 21.8 0.4 0.007 16.1 0.0 3.8 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 EIM79509.1 - 0.0004 19.6 8.3 0.016 14.4 0.0 3.5 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal DUF4042 PF13251.6 EIM79509.1 - 0.08 12.6 1.4 2.2 8.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) Utp12 PF04003.12 EIM79509.1 - 0.1 12.9 0.6 0.45 10.9 0.1 2.3 2 0 0 2 2 2 0 Dip2/Utp12 Family Adaptin_N PF01602.20 EIM79509.1 - 0.1 11.1 0.0 0.58 8.7 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region RTP1_C1 PF10363.9 EIM79509.1 - 0.11 12.7 0.2 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EIM79509.1 - 0.29 10.3 0.9 8 5.6 0.1 3.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain BTB PF00651.31 EIM79510.1 - 0.0054 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BSP_II PF05432.11 EIM79510.1 - 0.02 14.6 3.4 0.039 13.7 3.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 EIM79510.1 - 0.046 12.0 1.0 0.084 11.2 1.0 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EIM79510.1 - 0.54 9.5 10.2 1 8.6 10.2 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EIM79510.1 - 4.7 6.5 8.5 9.1 5.6 8.5 1.4 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 EIM79512.1 - 1.7e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 EIM79513.1 - 3.6e-17 62.9 0.0 7.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 EIM79513.1 - 9.1e-06 26.3 0.0 2.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PapJ PF14855.6 EIM79513.1 - 0.15 11.8 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Lsm_interact PF05391.11 EIM79516.1 - 0.076 12.5 0.1 0.43 10.1 0.1 2.4 1 0 0 1 1 1 0 Lsm interaction motif Ribosomal_L44 PF00935.19 EIM79516.1 - 0.4 11.2 3.2 1.2 9.6 3.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L44 Sec34 PF04136.15 EIM79518.1 - 8.2e-14 51.7 0.2 1.3e-13 51.1 0.2 1.2 1 0 0 1 1 1 1 Sec34-like family Zot PF05707.12 EIM79519.1 - 0.00094 18.9 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.29 EIM79519.1 - 0.0063 16.9 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM79519.1 - 0.14 12.4 0.2 8.1 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF3328 PF11807.8 EIM79520.1 - 1.3e-46 159.1 0.3 1.6e-46 158.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.23 EIM79523.1 - 1.2e-14 54.2 0.3 3e-14 52.9 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM79523.1 - 7.1e-09 35.6 0.1 1.3e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Nup_retrotrp_bd PF10599.9 EIM79523.1 - 0.33 11.6 3.2 1.7 9.3 1.1 2.6 2 0 0 2 2 2 0 Retro-transposon transporting motif ThrE PF06738.12 EIM79524.1 - 2.9e-50 170.9 23.0 1.2e-47 162.3 9.5 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM79524.1 - 1e-10 41.8 7.2 1e-10 41.8 7.2 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Peptidase_A4 PF01828.17 EIM79525.1 - 2.4e-75 252.6 17.2 2.9e-75 252.3 17.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family SKN1 PF03935.15 EIM79526.1 - 2.8e-181 603.3 13.2 6.9e-181 602.0 13.2 1.6 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Patatin PF01734.22 EIM79527.1 - 3.6e-21 76.3 0.0 2.5e-20 73.5 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase PaO PF08417.12 EIM79531.1 - 0.04 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Pheophorbide a oxygenase PHD_4 PF16866.5 EIM79531.1 - 3 8.0 8.0 0.32 11.1 2.9 2.0 2 0 0 2 2 2 0 PHD-finger Dor1 PF04124.12 EIM79533.1 - 4.7e-35 120.9 0.0 5.3e-28 97.7 0.0 3.2 2 2 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 EIM79533.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Vps51/Vps67 DUF992 PF06186.11 EIM79533.1 - 0.16 11.8 0.4 0.28 11.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF992) COG2 PF06148.11 EIM79533.1 - 0.18 11.9 0.3 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 EIM79533.1 - 0.54 10.3 2.5 1.3 9.0 2.5 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gly-zipper_Omp PF13488.6 EIM79534.1 - 0.088 12.8 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Glycine zipper Patatin PF01734.22 EIM79535.1 - 2.3e-11 44.3 0.0 2.5e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.6 EIM79537.1 - 1.7e-131 425.1 8.9 3.7e-12 45.7 0.0 12.9 12 1 1 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 EIM79537.1 - 6.2e-88 289.2 2.1 4e-13 49.4 0.1 10.8 6 4 5 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 EIM79537.1 - 3e-33 111.4 10.1 0.03 14.4 0.1 12.0 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_19 PF14559.6 EIM79537.1 - 6.2e-20 71.5 0.0 3.6 8.2 0.0 10.3 4 3 6 11 11 11 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM79537.1 - 2e-17 62.2 0.0 6.4 6.8 0.0 10.7 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM79537.1 - 3.7e-17 62.7 0.0 4.7 7.9 0.0 10.4 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_4 PF07721.14 EIM79537.1 - 1.1e-16 59.7 5.6 15 6.5 0.0 11.0 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM79537.1 - 1.4e-14 52.9 6.3 9.4 6.6 0.0 10.5 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIM79537.1 - 3.8e-12 45.7 17.3 3.3 8.3 0.1 9.5 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM79537.1 - 1.4e-06 28.0 2.0 41 4.7 0.1 8.4 11 0 0 11 11 11 0 Tetratricopeptide repeat Proteasome_A_N PF10584.9 EIM79537.1 - 0.00023 20.7 0.5 1.3e+02 2.3 0.0 5.9 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature TPR_14 PF13428.6 EIM79537.1 - 0.0011 19.6 9.9 2.3e+02 3.0 0.0 9.2 11 0 0 11 11 10 0 Tetratricopeptide repeat PPR PF01535.20 EIM79537.1 - 0.0015 18.6 0.0 81 3.8 0.0 6.3 10 0 0 10 10 9 0 PPR repeat DUF5401 PF17380.2 EIM79537.1 - 0.022 12.9 0.5 4.5 5.2 0.0 4.4 6 0 0 6 6 6 0 Family of unknown function (DUF5401) Acyl-CoA_dh_M PF02770.19 EIM79537.1 - 0.13 12.4 3.3 34 4.7 0.0 5.0 2 1 4 7 7 7 0 Acyl-CoA dehydrogenase, middle domain DHR-2 PF06920.13 EIM79537.1 - 1.5 7.4 5.3 1.1e+02 1.2 0.1 4.4 1 1 2 6 6 6 0 Dock homology region 2 Peptidase_S7 PF00949.21 EIM79537.1 - 1.7 8.5 3.7 78 3.1 2.2 3.4 2 1 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Goodbye PF17109.5 EIM79538.1 - 1.4e-18 67.5 0.0 4.3e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EIM79538.1 - 1.2e-09 38.3 0.0 3.6e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EIM79538.1 - 0.00045 20.5 0.1 0.0032 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIM79538.1 - 0.00068 20.1 1.2 0.0073 16.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.14 EIM79538.1 - 0.02 14.2 0.0 1.7 7.8 0.0 2.8 3 0 0 3 3 3 0 KAP family P-loop domain RNA_helicase PF00910.22 EIM79538.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase GlutR_dimer PF00745.20 EIM79538.1 - 0.054 14.0 1.4 0.48 10.9 0.3 3.0 3 0 0 3 3 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain ATPase PF06745.13 EIM79538.1 - 0.054 12.8 0.0 0.4 10.0 0.0 2.2 1 1 0 1 1 1 0 KaiC NB-ARC PF00931.22 EIM79538.1 - 0.075 12.2 0.1 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 EIM79538.1 - 0.082 13.2 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ASD2 PF08687.11 EIM79538.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Zeta_toxin PF06414.12 EIM79538.1 - 0.12 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 EIM79538.1 - 0.13 12.7 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Methyltransf_2 PF00891.18 EIM79539.1 - 4.2e-21 75.2 0.0 5.7e-20 71.5 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EIM79539.1 - 0.03 15.0 0.0 0.084 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation PF08100.11 EIM79539.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Abhydrolase_3 PF07859.13 EIM79540.1 - 5.7e-25 88.4 0.0 9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM79540.1 - 3.2e-11 42.7 0.0 3.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EIM79540.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_59 PF02057.15 EIM79541.1 - 1.4e-15 57.3 0.1 2e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EIM79541.1 - 4.2e-15 56.2 0.1 4.2e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 EIM79541.1 - 7.5e-11 42.1 1.5 2e-10 40.7 1.5 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EIM79541.1 - 6e-10 38.6 0.0 9.3e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Acetyltransf_10 PF13673.7 EIM79542.1 - 1e-07 31.9 0.0 4e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM79542.1 - 4.4e-07 30.2 0.0 9.1e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM79542.1 - 1.3e-06 28.7 0.0 4.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DOPA_dioxygen PF08883.11 EIM79543.1 - 2.6e-42 143.4 1.1 3.2e-42 143.1 1.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family TPR_10 PF13374.6 EIM79544.1 - 4.8e-20 70.8 0.7 6.6e-12 44.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM79544.1 - 6.4e-16 58.4 0.1 9.1e-09 35.5 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 EIM79544.1 - 1.2e-07 31.2 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EIM79544.1 - 3.8e-05 23.7 0.0 7.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.6 EIM79544.1 - 0.0024 17.8 0.7 0.89 9.7 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.6 EIM79544.1 - 0.018 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EIM79544.1 - 0.046 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EIM79544.1 - 0.048 13.1 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein TPR_4 PF07721.14 EIM79544.1 - 0.069 13.8 0.3 0.8 10.5 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIM79544.1 - 0.11 13.0 0.0 1.1 9.8 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EIM79544.1 - 0.19 12.2 0.1 26 5.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 EIM79545.1 - 1.1e-19 71.4 0.3 4e-18 66.3 0.3 2.3 1 1 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM79545.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Raptor_N PF14538.6 EIM79545.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain MRP-L20 PF12824.7 EIM79547.1 - 0.3 11.2 0.7 1 9.5 0.7 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 LOR PF04525.12 EIM79548.1 - 3.7e-27 95.1 0.0 4.6e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related MFS_1 PF07690.16 EIM79550.1 - 4.8e-21 75.1 21.7 6.7e-21 74.6 19.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EIM79551.1 - 1.8e-41 142.2 35.9 1.8e-41 142.2 35.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79551.1 - 2.5e-07 29.9 9.6 2.5e-07 29.9 9.6 3.1 2 2 2 4 4 4 1 Sugar (and other) transporter MFS_4 PF06779.14 EIM79551.1 - 2e-05 24.1 3.4 2e-05 24.1 3.4 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LOR PF04525.12 EIM79552.1 - 4.9e-14 52.4 0.0 6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related p450 PF00067.22 EIM79553.1 - 1.1e-66 225.5 0.0 1.4e-66 225.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EIM79555.1 - 0.00011 22.0 0.0 0.00043 20.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like RicinB_lectin_2 PF14200.6 EIM79557.1 - 5.6e-39 132.8 17.8 2.5e-08 34.5 0.3 7.7 1 1 11 12 12 12 11 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EIM79557.1 - 1.3e-05 25.5 0.0 0.14 12.4 0.0 3.7 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain NCBP3 PF10309.9 EIM79557.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 DUF2235 PF09994.9 EIM79559.1 - 7.9e-68 228.9 0.1 1.1e-67 228.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.16 EIM79559.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase WD40 PF00400.32 EIM79560.1 - 4.9e-116 375.3 42.9 4.2e-11 43.2 0.1 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79560.1 - 4e-49 164.9 0.8 0.00033 20.9 0.0 11.0 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM79560.1 - 4.7e-20 71.8 3.3 0.12 11.3 0.0 9.9 1 1 9 10 10 10 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIM79560.1 - 6.4e-17 61.0 10.8 2.1 8.4 0.1 10.8 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EIM79560.1 - 4.3e-16 59.4 0.0 0.00033 20.6 0.0 5.1 2 1 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EIM79560.1 - 2.1e-10 39.9 10.0 2.2 6.8 0.1 8.1 4 3 4 9 9 9 5 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM79560.1 - 1.5e-09 37.6 0.0 1.2 8.4 0.0 7.5 7 2 1 8 8 8 2 WD40-like domain Cytochrom_D1 PF02239.16 EIM79560.1 - 1.3e-07 30.5 0.7 0.0081 14.7 0.0 4.7 1 1 3 5 5 5 1 Cytochrome D1 heme domain Frtz PF11768.8 EIM79560.1 - 1.8e-07 29.9 0.0 0.16 10.2 0.0 5.2 5 1 1 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 EIM79560.1 - 3.8e-07 29.7 0.5 3.9 7.6 0.1 6.1 6 0 0 6 6 5 1 PQQ enzyme repeat Nbas_N PF15492.6 EIM79560.1 - 1.8e-05 24.3 6.3 3.2 7.0 0.2 6.8 1 1 6 8 8 8 1 Neuroblastoma-amplified sequence, N terminal nos_propeller PF18764.1 EIM79560.1 - 2.6e-05 24.0 2.3 18 5.3 0.0 6.7 7 1 1 8 8 7 0 Nitrous oxide reductase propeller repeat Ret2_MD PF18528.1 EIM79560.1 - 3.3e-05 24.2 0.0 13 6.2 0.0 6.3 7 3 3 10 10 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nucleoporin_N PF08801.11 EIM79560.1 - 3.6e-05 22.7 3.8 2.4 6.8 0.0 5.9 2 2 3 6 6 6 2 Nup133 N terminal like Proteasome_A_N PF10584.9 EIM79560.1 - 8.4e-05 22.2 18.9 15 5.4 0.0 9.7 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature DUF5122 PF17164.4 EIM79560.1 - 0.00038 20.7 12.5 1.7 9.0 0.1 7.7 9 0 0 9 9 9 1 Domain of unknown function (DUF5122) beta-propeller CHAP PF05257.16 EIM79560.1 - 0.00044 20.8 16.1 16 6.1 0.0 8.2 4 3 5 9 9 9 0 CHAP domain Cuticle_4 PF15955.5 EIM79560.1 - 0.0023 18.6 2.1 53 4.6 0.0 5.4 6 0 0 6 6 5 0 Cuticle protein IKI3 PF04762.12 EIM79560.1 - 0.0039 15.3 0.0 0.17 9.9 0.0 3.1 2 2 1 4 4 4 1 IKI3 family PQQ_2 PF13360.6 EIM79560.1 - 0.0095 15.5 8.6 0.23 11.0 2.5 3.5 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 EIM79560.1 - 0.013 16.0 12.4 1.4 9.5 0.0 6.0 6 3 2 8 8 6 0 PQQ-like domain HARP PF07443.13 EIM79560.1 - 0.025 14.2 1.3 60 3.4 0.0 5.1 7 0 0 7 7 7 0 HepA-related protein (HARP) DPPIV_N PF00930.21 EIM79560.1 - 0.03 13.1 1.7 35 3.0 0.1 5.4 3 2 2 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region GspH PF12019.8 EIM79560.1 - 0.037 14.4 11.2 10 6.6 0.0 5.6 2 1 3 5 5 5 0 Type II transport protein GspH DUF4265 PF14085.6 EIM79560.1 - 0.072 13.1 1.0 2.2 8.3 0.0 3.7 5 1 1 6 6 5 0 Domain of unknown function (DUF4265) DsbC_N PF10411.9 EIM79560.1 - 0.12 11.8 0.6 27 4.3 0.1 4.0 5 0 0 5 5 4 0 Disulfide bond isomerase protein N-terminus Resistin PF06954.11 EIM79560.1 - 0.22 12.1 1.8 40 4.9 0.0 3.5 2 1 1 3 3 3 0 Resistin FeoB_associated PF12669.7 EIM79564.1 - 0.011 16.2 0.4 0.011 16.2 0.4 3.0 3 1 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DUF3040 PF11239.8 EIM79564.1 - 0.04 14.2 2.2 0.04 14.2 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) UPF0767 PF15990.5 EIM79564.1 - 0.041 14.0 3.4 0.17 12.1 0.0 2.7 3 0 0 3 3 3 0 UPF0767 family DUF2207 PF09972.9 EIM79564.1 - 0.11 11.2 0.4 0.14 10.9 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Chordopox_A13L PF05961.11 EIM79564.1 - 0.73 10.1 0.1 0.73 10.1 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF2235 PF09994.9 EIM79565.1 - 1.7e-59 201.6 0.1 2.5e-59 201.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) WD40 PF00400.32 EIM79566.1 - 1.3e-107 348.7 44.0 1.2e-11 44.9 0.1 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79566.1 - 1.8e-46 156.3 1.0 0.00084 19.6 0.0 11.8 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM79566.1 - 3.5e-18 65.7 10.3 0.018 14.0 0.0 11.1 1 1 10 12 12 12 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM79566.1 - 5.8e-14 52.1 0.0 0.012 14.9 0.0 7.4 7 1 0 8 8 8 3 WD40-like domain PD40 PF07676.12 EIM79566.1 - 7.9e-12 44.8 19.0 1.8 8.6 0.1 10.4 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EIM79566.1 - 2e-11 44.1 0.0 0.0033 17.3 0.0 4.3 1 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EIM79566.1 - 4.4e-09 35.5 4.2 1.2 7.7 0.0 8.1 7 2 0 9 9 9 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EIM79566.1 - 4.7e-07 28.7 1.9 0.034 12.7 0.1 4.7 2 2 3 5 5 5 3 Cytochrome D1 heme domain PQQ PF01011.21 EIM79566.1 - 1e-06 28.3 4.0 1.3 9.1 0.1 5.9 6 1 1 7 7 6 2 PQQ enzyme repeat Nbas_N PF15492.6 EIM79566.1 - 3e-06 26.8 6.1 0.073 12.4 0.1 6.4 4 3 2 7 7 7 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 EIM79566.1 - 2.6e-05 23.9 8.0 0.042 13.4 0.6 4.5 2 1 1 3 3 3 2 PQQ-like domain Frtz PF11768.8 EIM79566.1 - 0.0001 20.8 0.0 20 3.3 0.0 6.1 4 2 0 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 EIM79566.1 - 0.0037 17.7 13.8 7.6 7.2 0.6 6.7 5 2 1 6 6 6 1 PQQ-like domain Peptidase_S9_N PF02897.15 EIM79566.1 - 0.0059 15.4 2.2 4.1 6.1 0.0 5.4 3 2 3 7 7 7 1 Prolyl oligopeptidase, N-terminal beta-propeller domain TcfC PF16967.5 EIM79566.1 - 0.034 13.6 0.0 5.6 6.5 0.0 3.4 3 0 0 3 3 3 0 E-set like domain Proteasome_A_N PF10584.9 EIM79566.1 - 0.056 13.1 18.5 34 4.2 0.0 8.2 9 0 0 9 9 8 0 Proteasome subunit A N-terminal signature Me-amine-dh_H PF06433.11 EIM79566.1 - 0.062 12.2 0.0 1.4 7.7 0.0 2.9 2 1 2 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) AcetylCoA_hyd_C PF13336.6 EIM79566.1 - 0.068 13.1 0.0 25 4.8 0.0 3.0 2 2 2 4 4 4 0 Acetyl-CoA hydrolase/transferase C-terminal domain IKI3 PF04762.12 EIM79566.1 - 0.071 11.1 0.1 2.5 6.0 0.0 2.5 2 1 0 2 2 2 0 IKI3 family TFIIIC_delta PF12657.7 EIM79566.1 - 3.2 7.7 7.2 36 4.2 0.3 3.9 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 EIM79569.1 - 3.1e-108 350.6 56.1 5.7e-10 39.6 0.0 13.7 13 0 0 13 13 13 12 WD domain, G-beta repeat DUF2235 PF09994.9 EIM79569.1 - 5.7e-53 180.1 4.7 1.5e-28 100.0 0.1 3.4 3 0 0 3 3 3 3 Uncharacterized alpha/beta hydrolase domain (DUF2235) ANAPC4_WD40 PF12894.7 EIM79569.1 - 7.8e-42 141.5 2.9 0.00094 19.4 0.0 12.3 1 1 10 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM79569.1 - 1.2e-14 54.1 10.4 0.21 10.5 0.2 11.2 1 1 12 13 13 13 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM79569.1 - 8.9e-14 51.5 0.1 0.04 13.3 0.0 8.0 8 3 2 10 10 10 4 WD40-like domain eIF2A PF08662.11 EIM79569.1 - 7.9e-09 35.7 0.0 0.019 14.9 0.0 4.4 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EIM79569.1 - 5.6e-06 25.1 1.5 0.43 9.1 0.0 4.2 2 1 3 5 5 5 2 Cytochrome D1 heme domain PD40 PF07676.12 EIM79569.1 - 2.2e-05 24.2 17.0 7.2 6.7 0.0 10.0 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 EIM79569.1 - 0.00015 21.4 10.2 0.56 9.7 0.1 4.5 2 1 0 4 4 4 2 PQQ-like domain Frtz PF11768.8 EIM79569.1 - 0.0012 17.3 0.0 17 3.5 0.0 5.2 5 1 1 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EIM79569.1 - 0.0023 17.3 6.6 7 5.9 0.0 6.6 5 2 1 7 7 7 1 Neuroblastoma-amplified sequence, N terminal MogR_DNAbind PF12181.8 EIM79569.1 - 0.035 14.0 0.1 13 5.7 0.0 2.6 1 1 1 2 2 2 0 DNA binding domain of the motility gene repressor (MogR) Peptidase_S9_N PF02897.15 EIM79569.1 - 0.051 12.4 1.6 2.4 6.8 0.3 3.4 1 1 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 EIM79569.1 - 0.057 13.4 0.1 33 4.7 0.0 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.6 EIM79569.1 - 0.079 13.5 5.7 1.3e+02 3.3 0.0 6.3 6 1 0 6 6 5 0 PQQ-like domain Proteasome_A_N PF10584.9 EIM79569.1 - 2.9 7.7 12.3 65 3.3 0.1 6.7 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF2937 PF11157.8 EIM79572.1 - 0.061 13.0 0.0 0.077 12.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) DUF2235 PF09994.9 EIM79573.1 - 1.6e-54 185.2 0.8 1.4e-53 182.2 0.8 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) WD40 PF00400.32 EIM79574.1 - 3.8e-114 369.3 45.1 9.6e-11 42.1 1.5 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79574.1 - 2.9e-53 178.1 3.3 0.00029 21.1 0.1 12.0 2 2 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM79574.1 - 1.3e-25 90.1 10.4 0.059 12.3 0.0 11.5 1 1 11 12 12 12 8 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EIM79574.1 - 5.1e-15 55.1 4.9 0.25 9.9 0.0 8.4 7 2 2 9 9 9 6 Nucleoporin Nup120/160 PD40 PF07676.12 EIM79574.1 - 9.7e-12 44.5 11.0 2.8 8.0 0.0 9.3 9 0 0 9 9 9 3 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EIM79574.1 - 7.3e-11 41.9 0.0 0.027 13.8 0.1 6.3 5 3 0 6 6 6 2 WD40-like domain eIF2A PF08662.11 EIM79574.1 - 3.1e-09 37.0 0.0 0.029 14.3 0.0 4.9 1 1 4 5 5 5 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EIM79574.1 - 9.6e-07 27.6 2.3 0.005 15.4 0.1 4.4 1 1 5 6 6 6 2 Cytochrome D1 heme domain Frtz PF11768.8 EIM79574.1 - 9.8e-07 27.5 0.0 4.5 5.5 0.0 5.4 4 2 1 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 EIM79574.1 - 1e-06 28.4 1.7 5.7 7.1 0.0 6.9 7 0 0 7 7 7 1 PQQ enzyme repeat PQQ_2 PF13360.6 EIM79574.1 - 7.7e-06 25.7 16.9 0.092 12.3 2.7 4.3 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.11 EIM79574.1 - 0.00015 20.7 6.0 1.1 7.9 0.0 6.6 2 2 5 8 8 8 1 Nup133 N terminal like Nbas_N PF15492.6 EIM79574.1 - 0.00022 20.7 13.0 14 4.9 0.0 8.0 5 3 5 10 10 10 0 Neuroblastoma-amplified sequence, N terminal DUF4784 PF16023.5 EIM79574.1 - 0.00046 19.3 0.0 0.54 9.2 0.0 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4784) nos_propeller PF18764.1 EIM79574.1 - 0.011 15.6 3.0 51 3.9 0.0 5.8 7 1 0 8 8 7 0 Nitrous oxide reductase propeller repeat Me-amine-dh_H PF06433.11 EIM79574.1 - 0.018 13.9 0.0 0.55 9.1 0.0 3.0 2 1 1 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Robl_LC7 PF03259.17 EIM79574.1 - 0.035 13.9 0.4 0.49 10.2 0.2 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain PQQ_3 PF13570.6 EIM79574.1 - 0.06 13.8 22.2 9 6.9 0.1 8.1 7 2 2 9 9 8 0 PQQ-like domain Hira PF07569.11 EIM79574.1 - 0.16 11.7 0.1 28 4.3 0.0 3.4 3 1 0 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.9 EIM79574.1 - 1.5 8.6 17.6 57 3.5 0.0 8.1 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.7 EIM79574.1 - 1.7 8.6 4.6 38 4.1 0.0 4.0 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term PS_Dcarbxylase PF02666.15 EIM79578.1 - 2.5e-36 125.1 0.0 3.6e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EIM79578.1 - 5.7e-29 100.9 0.0 9.5e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase p450 PF00067.22 EIM79579.1 - 1.5e-64 218.5 0.0 7.3e-64 216.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 HALZ PF02183.18 EIM79580.1 - 0.028 14.7 0.5 0.057 13.6 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4917 PF16263.5 EIM79580.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) bZIP_2 PF07716.15 EIM79580.1 - 1.7 8.8 6.1 0.23 11.6 1.6 1.8 2 0 0 2 2 2 0 Basic region leucine zipper PS_Dcarbxylase PF02666.15 EIM79582.1 - 1.1e-41 142.5 0.0 1.6e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EIM79582.1 - 1.9e-34 118.7 0.0 3.2e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase UbiA PF01040.18 EIM79583.1 - 5.7e-27 94.6 8.4 7.6e-27 94.2 8.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4131 PF13567.6 EIM79583.1 - 1.7 8.3 5.8 4.1 7.0 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3316 PF11777.8 EIM79585.1 - 0.17 11.9 1.8 4.4 7.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3316) PRR18 PF15671.5 EIM79585.1 - 0.84 9.5 5.2 1.5 8.6 5.2 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 Myosin_tail_1 PF01576.19 EIM79586.1 - 0.071 10.9 0.0 0.097 10.5 0.0 1.1 1 0 0 1 1 1 0 Myosin tail HOOK PF05622.12 EIM79586.1 - 0.12 10.5 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 HOOK protein p450 PF00067.22 EIM79589.1 - 1.1e-62 212.3 0.0 9.8e-62 209.2 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 EIM79590.1 - 3e-60 204.1 0.0 5e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM79590.1 - 2.3e-29 102.7 0.0 4.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM79590.1 - 0.00066 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EIM79590.1 - 0.015 15.5 0.1 0.042 14.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM79590.1 - 0.056 12.7 0.0 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM79590.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 EIM79590.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EIM79590.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAP PF07174.11 EIM79591.1 - 9.2 5.6 11.5 12 5.3 11.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MFS_1 PF07690.16 EIM79592.1 - 1.2e-28 100.0 66.7 6.9e-23 81.1 35.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79592.1 - 0.0013 17.7 8.2 0.0013 17.7 8.2 3.6 1 1 3 4 4 4 3 Sugar (and other) transporter Hydrolase_4 PF12146.8 EIM79594.1 - 1.8e-11 43.7 0.0 6.7e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM79594.1 - 4.6e-09 36.3 0.0 0.00017 21.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM79594.1 - 5.6e-08 33.7 0.1 8.8e-08 33.0 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIM79594.1 - 1.9e-07 30.8 0.0 3.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EIM79594.1 - 2.3e-07 30.7 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.10 EIM79594.1 - 0.027 13.6 0.0 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Tri3 PF07428.11 EIM79595.1 - 1.7e-25 89.8 0.0 2e-24 86.3 0.0 2.0 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 ketoacyl-synt PF00109.26 EIM79596.1 - 4.5e-48 164.0 0.0 7.3e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EIM79596.1 - 3.6e-27 94.7 0.3 1.8e-26 92.5 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EIM79596.1 - 0.026 13.9 0.1 0.18 11.1 0.2 2.2 3 0 0 3 3 3 0 Thiolase, N-terminal domain LOR PF04525.12 EIM79597.1 - 3.6e-21 75.6 0.0 4.4e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related Oxidored_FMN PF00724.20 EIM79598.1 - 3.5e-98 329.0 0.0 4.1e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 EIM79599.1 - 1.4e-99 333.7 0.0 1.6e-99 333.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4939 PF16297.5 EIM79601.1 - 6.6e-06 26.0 0.0 7.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DDE_3 PF13358.6 EIM79604.1 - 9.8e-09 35.1 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 EIM79605.1 - 0.00022 21.3 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EIM79605.1 - 0.00024 20.8 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 EIM79605.1 - 0.064 13.9 0.1 0.26 11.9 0.1 1.8 1 1 1 2 2 2 0 Homeodomain-like domain PAX PF00292.18 EIM79605.1 - 0.071 13.0 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain HTH_7 PF02796.15 EIM79605.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 EIM79605.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix UBX PF00789.20 EIM79606.1 - 9.2e-10 38.6 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF4800 PF16057.5 EIM79606.1 - 0.35 10.1 4.4 0.56 9.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) EF-hand_6 PF13405.6 EIM79607.1 - 7.4e-12 44.2 0.1 0.00011 21.9 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EIM79607.1 - 9.7e-12 45.2 0.0 1.1e-06 29.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EIM79607.1 - 5e-11 41.3 0.4 0.0003 20.1 0.0 3.8 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.6 EIM79607.1 - 6.4e-07 29.6 0.0 0.0028 17.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EIM79607.1 - 6.1e-06 26.0 0.0 0.00055 19.7 0.1 2.8 2 2 0 2 2 2 1 EF-hand domain pair UPF0154 PF03672.13 EIM79607.1 - 0.0054 16.7 0.0 2.4 8.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) SapB_1 PF05184.15 EIM79607.1 - 0.02 14.9 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 EFhand_Ca_insen PF08726.10 EIM79607.1 - 0.027 14.6 0.0 0.88 9.7 0.0 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Sigma70_r3 PF04539.16 EIM79607.1 - 0.07 13.2 0.3 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 EF-hand_5 PF13202.6 EIM79607.1 - 0.1 12.1 1.6 0.63 9.6 0.2 2.6 2 1 0 2 2 2 0 EF hand DDE_Tnp_IS66_C PF13817.6 EIM79607.1 - 0.16 12.2 0.1 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 IS66 C-terminal element RSN1_7TM PF02714.15 EIM79609.1 - 7.6e-80 268.1 23.1 1.7e-79 267.0 23.1 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EIM79609.1 - 3.4e-37 128.4 0.0 5.4e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EIM79609.1 - 5.1e-35 120.5 1.3 5.1e-35 120.5 1.3 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport adh_short PF00106.25 EIM79610.1 - 7.8e-29 100.5 0.0 3.2e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79610.1 - 2e-18 66.8 0.0 4.6e-14 52.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79610.1 - 8.4e-09 35.6 0.1 1.6e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EIM79610.1 - 2.2e-06 27.3 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM79610.1 - 0.00018 21.0 0.0 0.0007 19.1 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIM79610.1 - 0.0004 19.6 0.1 0.00056 19.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 EIM79610.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phage_TAC_7 PF10109.9 EIM79610.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 GMC_oxred_C PF05199.13 EIM79611.1 - 7.4e-28 97.9 0.0 8.8e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase AAA_22 PF13401.6 EIM79612.1 - 8.1e-05 22.9 0.1 0.59 10.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF853 PF05872.12 EIM79612.1 - 0.029 13.0 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 EIM79612.1 - 0.035 14.5 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_C48 PF02902.19 EIM79613.1 - 5.2e-08 33.0 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HMG_box_2 PF09011.10 EIM79614.1 - 0.0069 17.0 0.0 0.022 15.4 0.0 1.8 2 0 0 2 2 2 1 HMG-box domain SOTI PF17079.5 EIM79615.1 - 9.7 6.7 12.7 3.3 8.2 0.8 3.4 3 0 0 3 3 3 0 Male-specific protein scotti GMC_oxred_N PF00732.19 EIM79618.1 - 3.4e-19 69.3 0.1 4.7e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EIM79619.1 - 0.00022 20.7 0.0 0.00023 20.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Drf_FH3 PF06367.16 EIM79619.1 - 0.019 14.6 0.0 0.02 14.5 0.0 1.0 1 0 0 1 1 1 0 Diaphanous FH3 Domain PCRF PF03462.18 EIM79620.1 - 4.8e-48 163.6 2.3 1e-47 162.5 0.0 2.1 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EIM79620.1 - 1.5e-34 118.4 3.5 2.9e-34 117.4 3.5 1.5 1 0 0 1 1 1 1 RF-1 domain BING4CT PF08149.11 EIM79621.1 - 7e-39 131.5 0.0 3.4e-36 122.9 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 EIM79621.1 - 0.0014 19.4 2.6 0.28 12.1 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79621.1 - 0.0062 16.8 0.0 1.6 9.0 0.0 3.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 EIM79621.1 - 0.0079 16.3 10.5 0.0079 16.3 10.5 2.1 2 0 0 2 2 2 1 YL1 nuclear protein DUF5526 PF17664.1 EIM79621.1 - 0.76 9.3 9.3 1.5 8.3 9.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5526) Spt5_N PF11942.8 EIM79621.1 - 10 7.2 13.2 28 5.8 13.2 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Glyoxal_oxid_N PF07250.11 EIM79622.1 - 2e-26 92.6 0.3 1.1e-13 51.0 0.0 4.3 4 1 1 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM79622.1 - 1.1e-20 73.7 0.1 2.1e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF220 PF02713.14 EIM79625.1 - 0.15 12.2 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF220 DUF2396 PF09654.10 EIM79625.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) Plavaka PF18759.1 EIM79626.1 - 2.3e-121 405.0 0.0 3.4e-121 404.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4407 PF14362.6 EIM79627.1 - 0.18 11.1 1.7 0.34 10.2 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTP-bdg_M PF16360.5 EIM79627.1 - 0.48 11.1 4.9 0.36 11.4 2.9 1.8 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Rad17 PF03215.15 EIM79628.1 - 8.7e-29 100.8 0.0 3.1e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 EIM79628.1 - 0.00017 22.1 0.0 0.0011 19.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM79628.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIM79628.1 - 0.0012 19.1 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM79628.1 - 0.0017 18.7 0.2 0.0038 17.6 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EIM79628.1 - 0.0024 18.0 0.0 0.012 15.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EIM79628.1 - 0.0036 16.4 0.0 0.0082 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EIM79628.1 - 0.0043 17.5 0.0 0.0098 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EIM79628.1 - 0.03 14.7 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIM79628.1 - 0.038 14.5 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EIM79628.1 - 0.041 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIM79628.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EIM79628.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EIM79628.1 - 0.079 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EIM79628.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase TYW3 PF02676.14 EIM79628.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase TYW3 dNK PF01712.19 EIM79628.1 - 0.2 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase DSS1_SEM1 PF05160.13 EIM79630.1 - 1.9e-24 85.5 8.5 2.6e-24 85.0 8.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Alpha-amylase PF00128.24 EIM79632.1 - 1e-21 77.9 0.0 8.7e-21 74.8 0.0 2.3 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Pkinase PF00069.25 EIM79635.1 - 1.4e-12 47.5 0.0 5.1e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM79635.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3102 PF11300.8 EIM79635.1 - 0.2 11.9 0.4 16 5.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) HpcH_HpaI PF03328.14 EIM79636.1 - 1.3e-36 125.9 0.0 1.7e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MafB PF06255.13 EIM79636.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Neisseria toxin MafB Rad17 PF03215.15 EIM79637.1 - 3.8e-29 102.0 0.0 1.6e-23 83.6 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 EIM79637.1 - 0.00012 22.7 0.0 0.0013 19.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM79637.1 - 0.00042 20.1 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIM79637.1 - 0.0013 19.0 0.0 0.0034 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM79637.1 - 0.0016 18.9 0.1 0.0041 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EIM79637.1 - 0.0038 17.4 0.0 0.0099 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EIM79637.1 - 0.0039 16.3 0.0 0.0087 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EIM79637.1 - 0.0061 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF5308 PF17233.2 EIM79637.1 - 0.009 16.3 4.0 0.05 13.8 0.1 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5308) AAA_19 PF13245.6 EIM79637.1 - 0.023 15.1 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIM79637.1 - 0.038 14.5 0.0 0.089 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 EIM79637.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EIM79637.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EIM79637.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EIM79637.1 - 0.068 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EIM79637.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase dNK PF01712.19 EIM79637.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase DDT PF02791.17 EIM79638.1 - 0.088 13.1 0.0 0.56 10.6 0.0 2.4 1 1 0 1 1 1 0 DDT domain SOTI PF17079.5 EIM79639.1 - 0.92 9.9 9.4 2.4 8.6 0.6 3.4 2 1 1 3 3 3 0 Male-specific protein scotti 3-HAO PF06052.12 EIM79641.1 - 1.1e-52 177.7 0.0 1.2e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase ThiF PF00899.21 EIM79642.1 - 2.8e-70 236.4 0.0 3.9e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EIM79642.1 - 9.9e-17 61.7 0.0 2.5e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 EIM79642.1 - 2.3e-05 24.9 0.0 5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 EIM79642.1 - 0.048 14.1 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding PRIMA1 PF16101.5 EIM79642.1 - 4 7.5 6.6 9.8 6.2 6.6 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_hydro_71 PF03659.14 EIM79643.1 - 1.3e-107 359.9 10.2 1.5e-107 359.7 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 ATPase PF06745.13 EIM79645.1 - 0.14 11.5 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 KaiC RXT2_N PF08595.11 EIM79645.1 - 1.7 8.7 3.4 3.6 7.6 3.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal SOTI PF17079.5 EIM79646.1 - 0.57 10.6 7.3 6.1 7.3 0.8 2.9 2 0 0 2 2 2 0 Male-specific protein scotti Cu-oxidase PF00394.22 EIM79648.1 - 1.4e-45 155.2 0.5 7.3e-43 146.4 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM79648.1 - 1.3e-36 125.4 0.9 7.5e-31 106.7 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM79648.1 - 1.4e-35 121.9 1.2 1.2e-33 115.7 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase adh_short PF00106.25 EIM79649.1 - 3.5e-16 59.3 0.0 1.6e-11 44.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79649.1 - 1.2e-09 38.1 0.1 4.3e-06 26.5 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79649.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Pox_P4A PF03395.14 EIM79649.1 - 0.17 9.5 0.0 0.2 9.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein VHS PF00790.19 EIM79650.1 - 9.2e-39 132.5 0.0 1.3e-37 128.8 0.0 2.2 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EIM79650.1 - 2.2e-18 66.3 0.5 1.5e-17 63.7 0.0 2.5 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 EIM79650.1 - 0.0056 16.3 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 GGA N-GAT domain Abhydrolase_6 PF12697.7 EIM79651.1 - 1.1e-09 39.2 0.3 1.1e-09 39.2 0.3 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ydr279_N PF17745.1 EIM79651.1 - 0.036 14.3 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Ydr279p protein triple barrel domain Med7 PF05983.11 EIM79652.1 - 0.077 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 MED7 protein AMP-binding PF00501.28 EIM79653.1 - 2.4e-63 214.2 0.1 1.8e-32 112.5 0.2 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EIM79653.1 - 1.8e-13 51.3 0.0 3.5e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AidB_N PF18158.1 EIM79654.1 - 6.3e-27 94.4 0.0 1.6e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EIM79654.1 - 7.6e-18 65.1 1.3 1.7e-17 64.0 1.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIM79654.1 - 3.5e-12 46.3 0.0 1.2e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIM79654.1 - 2.6e-05 24.5 0.0 5.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EIM79654.1 - 0.0022 18.6 0.0 0.012 16.2 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain p450 PF00067.22 EIM79655.1 - 2.1e-59 201.5 0.0 1.2e-58 199.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 EIM79657.1 - 1.8e-34 120.1 0.1 3e-34 119.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Collagen_mid PF15984.5 EIM79658.1 - 0.0044 16.8 10.2 0.0063 16.3 10.2 1.3 1 0 0 1 1 1 1 Bacterial collagen, middle region DUF4349 PF14257.6 EIM79658.1 - 0.012 15.1 1.1 0.021 14.3 1.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Phage_GP20 PF06810.11 EIM79658.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 FlxA PF14282.6 EIM79658.1 - 0.31 11.1 3.2 0.28 11.2 1.5 1.8 1 1 1 2 2 2 0 FlxA-like protein Clr2_transil PF16761.5 EIM79659.1 - 4.9e-14 52.9 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 adh_short PF00106.25 EIM79661.1 - 3.7e-28 98.3 0.0 6.8e-27 94.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79661.1 - 6.3e-19 68.5 0.1 1.3e-17 64.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM79661.1 - 2.2e-06 27.3 0.0 1.9e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM79661.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EIM79661.1 - 0.014 14.6 0.1 0.076 12.2 0.1 2.0 1 1 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.6 EIM79661.1 - 0.073 13.0 0.2 0.099 12.5 0.2 1.5 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIM79661.1 - 0.18 11.2 0.0 2.1 7.7 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Hydrolase_4 PF12146.8 EIM79663.1 - 3.9e-13 49.2 0.0 6e-10 38.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM79663.1 - 1.1e-11 44.8 0.0 2.5e-09 37.2 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM79663.1 - 1.1e-05 26.1 1.9 2.2e-05 25.2 1.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EIM79663.1 - 0.0017 18.3 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EIM79663.1 - 0.0049 16.7 0.1 2.7 7.7 0.0 3.0 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EIM79663.1 - 0.0084 15.6 0.0 0.042 13.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EIM79663.1 - 0.011 15.4 0.0 0.09 12.4 0.0 2.3 3 0 0 3 3 3 0 Serine hydrolase (FSH1) DLH PF01738.18 EIM79663.1 - 0.028 14.0 0.0 0.28 10.7 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 EIM79663.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 EIM79663.1 - 0.077 11.6 0.4 1 7.9 0.0 2.0 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 EIM79663.1 - 0.13 11.8 0.0 0.5 9.9 0.0 1.9 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Rad17 PF03215.15 EIM79666.1 - 7.2e-26 91.3 2.5 2.9e-18 66.5 0.5 3.4 3 1 0 3 3 3 2 Rad17 P-loop domain AAA_18 PF13238.6 EIM79666.1 - 9.8e-05 22.9 0.0 0.0023 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM79666.1 - 0.00047 20.4 0.0 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM79666.1 - 0.00057 19.7 0.0 0.00091 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIM79666.1 - 0.0011 19.1 0.1 0.011 15.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EIM79666.1 - 0.002 18.5 0.2 0.0051 17.2 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EIM79666.1 - 0.0021 18.5 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EIM79666.1 - 0.0022 17.1 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EIM79666.1 - 0.01 16.2 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIM79666.1 - 0.016 15.7 0.1 0.043 14.3 0.1 1.6 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 EIM79666.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EIM79666.1 - 0.024 14.6 0.3 0.061 13.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EIM79666.1 - 0.028 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EIM79666.1 - 0.045 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_17 PF13207.6 EIM79666.1 - 0.046 14.2 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 EIM79666.1 - 0.069 11.1 0.0 0.096 10.6 0.0 1.1 1 0 0 1 1 1 0 Helicase dNK PF01712.19 EIM79666.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_6 PF12774.7 EIM79666.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_23 PF13476.6 EIM79666.1 - 0.13 12.7 0.1 0.27 11.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 EIM79666.1 - 0.2 11.2 0.1 0.31 10.6 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EIM79666.1 - 0.21 11.6 0.1 0.46 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM79667.1 - 0.00019 21.7 0.0 0.86 9.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain HMG_box_2 PF09011.10 EIM79667.1 - 0.019 15.5 0.1 0.13 12.9 0.0 2.2 2 0 0 2 2 2 0 HMG-box domain DUF853 PF05872.12 EIM79667.1 - 0.036 12.7 0.0 0.069 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 EIM79667.1 - 0.15 12.5 0.0 0.57 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EIM79669.1 - 3e-08 33.7 0.0 6.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain CHAT PF12770.7 EIM79669.1 - 5.6e-07 29.3 0.5 1.5e-06 27.9 0.5 1.6 1 0 0 1 1 1 1 CHAT domain AAA_25 PF13481.6 EIM79669.1 - 2e-05 24.3 0.0 2e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM79669.1 - 0.00021 21.6 1.5 0.0011 19.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain PMC2NT PF08066.12 EIM79669.1 - 0.015 15.9 3.8 0.74 10.5 1.3 2.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain NB-ARC PF00931.22 EIM79669.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Goodbye PF17109.5 EIM79669.1 - 0.079 13.4 3.4 0.91 10.0 0.0 2.7 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Exonuc_VII_L PF02601.15 EIM79669.1 - 0.088 12.4 7.1 0.26 10.8 7.1 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA PF00004.29 EIM79669.1 - 0.12 12.8 1.2 1.1 9.6 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF3552 PF12072.8 EIM79669.1 - 0.78 9.1 18.4 2.3 7.6 18.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF2828 PF11443.8 EIM79669.1 - 1.4 6.9 8.4 2.4 6.2 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Spc7 PF08317.11 EIM79669.1 - 1.5 7.6 12.5 2.5 6.9 12.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EIM79669.1 - 3.8 7.7 18.3 9.2 6.5 18.3 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 SOTI PF17079.5 EIM79671.1 - 4.1 7.8 8.7 29 5.2 0.7 3.5 3 0 0 3 3 3 0 Male-specific protein scotti MFS_1 PF07690.16 EIM79674.1 - 2.1e-13 50.0 20.5 2.7e-13 49.6 20.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Orai-1 PF07856.12 EIM79674.1 - 1.5 8.4 6.9 0.15 11.7 0.7 2.2 2 1 0 2 2 2 0 Mediator of CRAC channel activity FOXP-CC PF16159.5 EIM79675.1 - 0.054 14.1 2.6 0.29 11.8 0.3 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain TF_Zn_Ribbon PF08271.12 EIM79675.1 - 0.6 9.7 3.0 0.46 10.0 0.7 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Transpos_assoc PF13963.6 EIM79675.1 - 0.71 10.2 4.5 13 6.2 1.0 2.4 2 0 0 2 2 2 0 Transposase-associated domain zf-C2H2_4 PF13894.6 EIM79675.1 - 1.5 9.9 15.1 8.2 7.6 1.5 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger UQ_con PF00179.26 EIM79676.1 - 4e-48 162.6 0.0 4.5e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIM79676.1 - 0.0011 18.7 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EIM79676.1 - 0.018 14.9 0.1 0.035 14.0 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EIM79676.1 - 0.12 12.6 0.2 0.18 12.1 0.2 1.4 1 1 0 1 1 1 0 RWD domain Skp1_POZ PF03931.15 EIM79677.1 - 1.4e-06 28.3 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ifi-6-16 PF06140.13 EIM79678.1 - 0.0066 16.3 7.7 0.0066 16.3 7.7 2.3 2 1 1 3 3 3 1 Interferon-induced 6-16 family Glyco_hydro_71 PF03659.14 EIM79679.1 - 3.7e-115 384.7 17.1 4.1e-115 384.6 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CutC PF03932.14 EIM79679.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 CutC family zf-RING_2 PF13639.6 EIM79681.1 - 3.8e-07 30.3 4.3 6.1e-07 29.7 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EIM79681.1 - 1.2e-06 28.2 2.9 2e-06 27.4 2.9 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EIM79681.1 - 1.7e-05 24.8 4.2 2.8e-05 24.1 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIM79681.1 - 0.0072 16.3 3.1 0.011 15.7 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM79681.1 - 0.0072 16.1 2.2 0.015 15.1 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EIM79681.1 - 0.0082 16.0 3.4 0.014 15.2 3.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.25 EIM79681.1 - 0.01 15.7 2.6 0.017 15.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM79681.1 - 0.16 12.0 3.4 0.64 10.1 3.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EIM79681.1 - 0.36 11.1 6.8 2.3 8.6 5.0 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain Sacchrp_dh_NADP PF03435.18 EIM79682.1 - 6.9e-19 68.4 0.0 1.1e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain YbbR PF07949.12 EIM79683.1 - 0.067 13.5 0.8 0.067 13.5 0.8 2.3 2 1 0 2 2 2 0 YbbR-like protein Synaphin PF05835.12 EIM79684.1 - 0.0078 16.5 5.5 0.0078 16.5 5.5 2.6 2 0 0 2 2 2 1 Synaphin protein DNA_pol_phi PF04931.13 EIM79690.1 - 4.7 5.2 8.9 7 4.6 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi SOTI PF17079.5 EIM79691.1 - 0.18 12.2 5.1 3.2 8.2 0.7 3.1 2 0 0 2 2 2 0 Male-specific protein scotti Baculo_PEP_C PF04513.12 EIM79693.1 - 0.00073 19.6 1.6 0.0011 19.0 1.6 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5327 PF17261.2 EIM79693.1 - 0.12 13.1 0.1 11 6.8 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5327) Ifi-6-16 PF06140.13 EIM79694.1 - 1.4e-07 31.3 10.6 0.0014 18.5 0.8 2.6 2 0 0 2 2 2 2 Interferon-induced 6-16 family Transgly_assoc PF04226.13 EIM79694.1 - 0.65 10.3 6.0 1.1 9.5 0.1 3.1 3 0 0 3 3 3 0 Transglycosylase associated protein SSF PF00474.17 EIM79698.1 - 3.5e-21 75.5 34.1 6.5e-21 74.7 34.1 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.9 EIM79698.1 - 0.042 12.6 0.0 0.042 12.6 0.0 4.0 3 2 1 4 4 4 0 Predicted membrane protein (DUF2207) F-box-like PF12937.7 EIM79699.1 - 0.035 14.0 0.0 0.13 12.2 0.0 2.0 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 EIM79702.1 - 0.00045 20.0 1.4 0.00088 19.1 1.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM79702.1 - 0.0045 16.9 0.8 0.009 15.9 0.8 1.5 1 0 0 1 1 1 1 F-box-like OmpH PF03938.14 EIM79702.1 - 1.8 8.9 7.4 2.9 8.2 7.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) WD40 PF00400.32 EIM79703.1 - 1.2e-16 60.8 16.4 0.00031 21.5 1.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79703.1 - 2e-10 40.8 0.1 0.046 14.0 0.0 4.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM79703.1 - 0.00023 20.2 0.3 2.1 7.2 0.0 3.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIM79703.1 - 0.00047 20.0 0.1 0.87 9.6 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF3261 PF11659.8 EIM79703.1 - 0.01 15.7 0.0 3.8 7.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3261) Nbas_N PF15492.6 EIM79703.1 - 0.027 13.8 1.6 1.6 8.0 0.0 2.9 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EIM79703.1 - 0.048 13.0 0.0 0.065 12.5 0.0 1.3 1 1 0 1 1 1 0 WD40-like domain Nucleoporin_N PF08801.11 EIM79703.1 - 0.058 12.1 0.1 0.15 10.7 0.0 1.7 1 1 1 2 2 2 0 Nup133 N terminal like PALB2_WD40 PF16756.5 EIM79703.1 - 0.096 11.6 0.7 0.93 8.4 0.6 2.1 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Proteasome_A_N PF10584.9 EIM79703.1 - 0.17 11.6 0.0 27 4.5 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 EIM79704.1 - 6.5e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 NACHT domain CbiA PF01656.23 EIM79704.1 - 0.0028 17.7 0.1 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EIM79704.1 - 0.012 16.0 0.0 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EIM79704.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA PF00004.29 EIM79704.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EIM79704.1 - 0.039 14.5 0.1 0.044 14.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EIM79704.1 - 0.063 13.2 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 EIM79704.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EIM79704.1 - 0.092 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain HHH_2 PF12826.7 EIM79704.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif NB-ARC PF00931.22 EIM79704.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EIM79704.1 - 0.17 11.5 1.1 1.7 8.2 1.1 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EIM79704.1 - 0.19 10.9 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_C14 PF00656.22 EIM79706.1 - 5.8e-19 69.0 0.0 1e-18 68.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain PsaM PF07465.13 EIM79707.1 - 0.062 13.0 1.4 0.16 11.7 1.4 1.7 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) zf-C2H2_4 PF13894.6 EIM79710.1 - 1.3e-13 50.6 44.3 0.0092 16.7 0.1 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM79710.1 - 1.1e-12 47.9 38.7 0.17 12.2 1.8 7.3 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EIM79710.1 - 1.2e-06 28.7 36.5 0.031 14.6 0.4 6.8 2 2 4 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EIM79710.1 - 9e-06 25.9 43.9 0.063 13.8 3.2 7.5 7 0 0 7 7 7 3 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 EIM79710.1 - 0.0025 17.6 10.7 1.8 8.5 0.2 5.2 3 2 2 5 5 5 1 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 EIM79710.1 - 0.0053 16.7 34.7 0.1 12.6 3.2 6.5 6 0 0 6 6 6 1 C2H2-type zinc finger Zn_ribbon_2 PF12674.7 EIM79710.1 - 0.034 14.8 9.5 0.59 10.8 3.9 2.8 2 1 0 2 2 2 0 Putative zinc ribbon domain zf-C2H2_9 PF16293.5 EIM79710.1 - 0.077 12.9 25.1 1.4 8.9 0.1 6.4 3 3 4 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 EIM79710.1 - 0.14 12.6 0.3 0.14 12.6 0.3 6.6 7 1 0 7 7 6 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 EIM79710.1 - 0.34 10.9 20.0 1.3 9.0 0.2 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-met PF12874.7 EIM79710.1 - 0.56 10.7 41.0 0.33 11.4 2.2 7.1 8 0 0 8 8 6 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.6 EIM79710.1 - 0.86 9.6 0.1 0.86 9.6 0.1 5.6 7 0 0 7 7 7 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EIM79710.1 - 1.1 9.5 24.8 0.27 11.4 0.3 5.0 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 EIM79710.1 - 2.2 8.1 0.0 2.2 8.1 0.0 5.7 6 0 0 6 6 6 0 zinc-finger C2H2-type DUF4187 PF13821.6 EIM79710.1 - 2.6 7.9 22.4 1.2 9.0 1.5 4.6 3 2 2 5 5 4 0 Domain of unknown function (DUF4187) Anti-TRAP PF15777.5 EIM79710.1 - 3 7.9 6.0 6.2 6.9 0.1 3.6 4 0 0 4 4 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-ribbon_3 PF13248.6 EIM79710.1 - 3.3 7.3 10.6 8.8 5.9 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_3rep PF18868.1 EIM79710.1 - 3.4 8.3 21.3 0.6 10.8 3.3 4.1 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats C1_4 PF07975.12 EIM79710.1 - 3.8 7.8 26.7 5.1 7.4 0.4 4.8 4 2 1 5 5 4 0 TFIIH C1-like domain Zn-C2H2_12 PF18112.1 EIM79710.1 - 8.2 7.0 20.6 0.71 10.4 0.6 5.6 7 0 0 7 7 5 0 Autophagy receptor zinc finger-C2H2 domain SnoaL PF07366.12 EIM79711.1 - 1.2e-06 28.4 0.1 1.6e-06 27.9 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EIM79711.1 - 0.00018 22.1 0.1 0.00028 21.5 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Adeno_hexon PF01065.19 EIM79711.1 - 0.098 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Kdo PF06293.14 EIM79712.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM79712.1 - 0.096 12.6 0.2 0.48 10.3 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 EIM79714.1 - 1.8e-06 27.5 0.0 0.0076 15.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain LOR PF04525.12 EIM79716.1 - 0.039 13.6 0.0 0.045 13.3 0.0 1.0 1 0 0 1 1 1 0 LURP-one-related WD40 PF00400.32 EIM79717.1 - 1.2e-12 48.0 10.3 0.036 14.9 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM79717.1 - 8.6e-06 26.0 0.0 0.23 11.8 0.0 3.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIM79717.1 - 0.0026 17.6 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 EIM79717.1 - 0.0072 15.1 0.0 0.0081 14.9 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nbas_N PF15492.6 EIM79717.1 - 0.082 12.2 0.5 6.6 6.0 0.0 2.4 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 EIM79717.1 - 0.09 12.5 0.0 18 5.1 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 EIM79717.1 - 0.093 11.7 0.3 4.2 6.2 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arena_nucleocap PF00843.17 EIM79717.1 - 0.18 10.7 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain NACHT PF05729.12 EIM79718.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 EIM79719.1 - 0.012 15.7 0.1 0.075 13.1 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EIM79719.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EIM79719.1 - 0.042 13.0 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PEPCK_ATP PF01293.20 EIM79719.1 - 0.077 11.7 0.1 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_30 PF13604.6 EIM79719.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EIM79719.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 EIM79719.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EIM79719.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EIM79719.1 - 0.12 12.9 0.1 0.39 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EIM79719.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Methyltransf_2 PF00891.18 EIM79720.1 - 2.5e-09 36.8 0.5 2.2e-06 27.1 0.1 3.1 3 1 0 3 3 3 2 O-methyltransferase domain MFS_1 PF07690.16 EIM79721.1 - 6.9e-30 104.2 18.5 6.9e-30 104.2 18.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79721.1 - 8.4e-12 44.7 13.4 3.2e-06 26.3 4.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Nuc_H_symport PF03825.16 EIM79721.1 - 0.0021 17.1 6.3 0.03 13.3 5.9 2.4 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF2530 PF10745.9 EIM79721.1 - 0.21 11.8 6.5 2.6 8.3 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Oxidored_FMN PF00724.20 EIM79722.1 - 4.9e-59 200.3 0.0 6.9e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EIM79722.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Response_reg PF00072.24 EIM79723.1 - 1.9e-20 73.1 1.0 3.4e-20 72.3 1.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EIM79723.1 - 2.7e-20 72.9 0.0 1.9e-19 70.2 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EIM79723.1 - 3.7e-06 26.9 0.0 1.1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EIM79723.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF4579 PF15158.6 EIM79723.1 - 0.18 11.5 1.2 0.42 10.4 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) AMP-binding PF00501.28 EIM79724.1 - 7.1e-40 136.9 0.0 2e-39 135.4 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EIM79724.1 - 2.4e-27 95.7 0.0 5.4e-27 94.6 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EIM79724.1 - 3.6e-07 29.9 0.0 7.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM79724.1 - 0.00015 22.0 0.0 0.0012 19.1 0.0 2.6 2 1 0 2 2 2 1 Phosphopantetheine attachment site NmrA PF05368.13 EIM79724.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 EIM79724.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 EIM79724.1 - 0.15 12.0 0.0 0.47 10.3 0.0 1.9 1 0 0 1 1 1 0 KR domain zf-MYND PF01753.18 EIM79725.1 - 1.9e-06 27.8 15.5 3.7e-06 26.9 15.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM79725.1 - 0.027 14.7 9.6 0.053 13.8 9.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 EIM79725.1 - 1.1 9.5 6.4 2.2 8.4 6.4 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 WD40 PF00400.32 EIM79726.1 - 6.5e-07 30.0 0.3 0.099 13.6 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Elongin_A PF06881.11 EIM79726.1 - 2.9e-06 27.8 0.0 6.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 EIM79726.1 - 4.7e-06 26.4 0.3 0.0002 21.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM79726.1 - 0.0001 22.1 0.2 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EIM79726.1 - 0.012 15.8 0.0 3.9 7.9 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 EIM79727.1 - 9.9e-85 284.7 0.0 1.2e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM79727.1 - 2.5e-14 54.0 0.1 8.6e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Rx_N PF18052.1 EIM79728.1 - 3.6 7.9 8.9 10 6.5 8.9 1.8 1 1 0 1 1 1 0 Rx N-terminal domain DUF4946 PF16304.5 EIM79729.1 - 0.039 13.7 4.7 0.081 12.6 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) Macoilin PF09726.9 EIM79731.1 - 0.025 13.2 11.8 0.13 10.8 11.8 1.9 1 1 0 1 1 1 0 Macoilin family HIP1_clath_bdg PF16515.5 EIM79731.1 - 0.63 10.7 10.8 1.6 9.4 3.4 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 EIM79731.1 - 1.9 8.9 12.4 1.3 9.5 10.0 1.7 2 0 0 2 2 2 0 Fez1 ERM PF00769.19 EIM79731.1 - 7.5 6.3 18.1 33 4.2 18.1 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Macoilin PF09726.9 EIM79734.1 - 0.021 13.4 4.2 0.028 13.0 4.2 1.1 1 0 0 1 1 1 0 Macoilin family TPR_MLP1_2 PF07926.12 EIM79734.1 - 0.025 14.6 6.5 0.12 12.4 2.8 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EIM79734.1 - 0.65 8.8 9.9 0.21 10.5 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EIM79734.1 - 1.9 9.1 10.3 0.4 11.3 1.3 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TSC22 PF01166.18 EIM79736.1 - 2.4 8.5 7.5 1.6 9.1 3.2 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.18 EIM79736.1 - 3.4 8.0 10.9 0.38 11.0 3.4 3.0 2 2 1 3 3 3 0 Homeobox associated leucine zipper GMC_oxred_N PF00732.19 EIM79738.1 - 1.3e-56 192.2 0.0 1.7e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM79738.1 - 3.2e-36 125.0 0.0 5.7e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM79738.1 - 2.7e-05 23.4 0.1 4e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EIM79738.1 - 8.7e-05 21.9 0.2 0.067 12.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM79738.1 - 0.00021 21.5 0.1 0.00055 20.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM79738.1 - 0.00021 20.5 1.3 0.046 12.8 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EIM79738.1 - 0.00028 20.6 0.5 0.0012 18.5 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM79738.1 - 0.0023 17.2 0.1 0.0048 16.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EIM79738.1 - 0.0041 16.4 0.2 0.088 12.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM79738.1 - 0.021 13.6 0.5 0.93 8.1 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Cauli_VI PF01693.16 EIM79740.1 - 8.2e-15 54.8 0.6 3e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin KDZ PF18758.1 EIM79741.1 - 1.9e-48 165.0 0.0 3.1e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM79741.1 - 6.6e-35 119.5 0.0 1.3e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM79741.1 - 6.2e-06 26.3 0.1 1.3e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EIM79741.1 - 0.021 14.7 0.1 0.061 13.2 0.1 1.8 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 EIM79741.1 - 1.5 9.0 6.0 3.8 7.7 6.0 1.7 1 0 0 1 1 1 0 B-box zinc finger CEBP_ZZ PF16366.5 EIM79741.1 - 1.6 9.0 5.2 4 7.8 5.2 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DDE_3 PF13358.6 EIM79742.1 - 1.3e-07 31.5 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 EIM79743.1 - 2.7e-10 40.4 0.0 3.2e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EIM79743.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Plavaka PF18759.1 EIM79745.1 - 2e-41 142.3 0.0 3.1e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Importin_rep_4 PF18808.1 EIM79749.1 - 1.1e-13 51.3 0.1 7.2e-13 48.6 0.0 2.5 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 EIM79749.1 - 5.7e-12 44.8 1.6 3.3e-05 23.8 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EIM79749.1 - 4.8e-11 42.9 8.8 0.00011 22.6 0.0 6.8 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EIM79749.1 - 5e-09 36.6 0.0 0.00013 22.5 0.0 3.8 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EIM79749.1 - 4.5e-07 30.2 0.6 0.0062 16.9 0.0 4.6 3 1 2 5 5 5 2 HEAT repeats DUF3385 PF11865.8 EIM79749.1 - 8.2e-06 25.8 0.0 6.7 6.6 0.0 4.3 2 1 2 4 4 4 3 Domain of unknown function (DUF3385) RIX1 PF08167.12 EIM79749.1 - 0.0001 22.1 0.0 0.0018 18.0 0.0 2.9 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 EIM79749.1 - 0.00054 19.2 6.1 0.011 14.9 0.0 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 EIM79749.1 - 0.034 14.2 0.0 0.32 11.0 0.0 2.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EIM79749.1 - 0.097 12.9 0.1 0.75 10.0 0.0 2.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 EIM79750.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Nic96 PF04097.14 EIM79752.1 - 3.3e-07 29.2 0.0 3.4e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 SAM_2 PF07647.17 EIM79753.1 - 2.2e-11 43.7 0.0 4.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EIM79753.1 - 3.4e-09 37.0 0.6 6.2e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 EIM79753.1 - 8.1e-07 29.5 0.2 2.3e-06 28.0 0.2 1.8 1 0 0 1 1 1 1 PH domain SAM_3 PF18016.1 EIM79753.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 EIM79753.1 - 0.0016 18.0 0.2 0.0036 16.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SAM_Ste50p PF09235.10 EIM79753.1 - 0.0094 16.2 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif DUF1924 PF09086.11 EIM79754.1 - 0.23 11.9 1.7 0.34 11.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1924) ERM PF00769.19 EIM79756.1 - 0.0084 16.0 9.3 0.012 15.4 9.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DMPK_coil PF08826.10 EIM79756.1 - 0.0098 16.0 4.7 0.81 9.8 0.6 3.0 2 1 0 2 2 2 2 DMPK coiled coil domain like cwf18 PF08315.12 EIM79756.1 - 0.013 16.1 1.8 0.02 15.5 1.8 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor APG6_N PF17675.1 EIM79756.1 - 0.052 14.1 2.0 0.073 13.6 2.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 EIM79756.1 - 0.067 12.5 4.7 0.11 11.8 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 EIM79756.1 - 0.13 12.3 0.2 0.21 11.6 0.2 1.2 1 0 0 1 1 1 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 EIM79756.1 - 0.48 10.6 9.2 0.53 10.5 6.3 2.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4315 PF14193.6 EIM79756.1 - 0.5 10.4 9.3 23 5.1 1.6 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4315) M PF02370.16 EIM79756.1 - 0.72 10.6 10.1 0.19 12.4 2.5 3.2 2 1 1 3 3 3 0 M protein repeat Tropomyosin_1 PF12718.7 EIM79756.1 - 0.78 9.9 10.7 4.2 7.5 3.3 2.2 1 1 1 2 2 2 0 Tropomyosin like ABC_tran PF00005.27 EIM79757.1 - 9.1e-07 29.5 0.0 1.1e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter zf-XS PF03470.14 EIM79761.1 - 0.084 13.2 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 XS zinc finger domain RNA_lig_T4_1 PF09511.10 EIM79762.1 - 4.3e-23 82.3 0.0 4.8e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DEAD PF00270.29 EIM79763.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1664 PF07889.12 EIM79765.1 - 0.0005 20.1 1.9 0.0005 20.1 1.9 6.5 4 3 2 6 6 6 2 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 EIM79765.1 - 0.0056 16.5 1.7 0.0056 16.5 1.7 5.4 2 2 3 5 5 5 3 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EIM79765.1 - 0.012 14.5 65.9 0.013 14.4 15.9 4.7 3 1 1 4 4 4 0 Spc7 kinetochore protein Atg14 PF10186.9 EIM79765.1 - 5.4 6.0 50.8 0.77 8.8 4.1 4.6 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 ANAPC4_WD40 PF12894.7 EIM79768.1 - 0.00021 21.5 0.0 0.82 10.0 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM79768.1 - 0.0046 17.8 7.4 30 5.7 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EIM79768.1 - 0.022 15.2 2.0 0.14 12.7 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 EIM79768.1 - 0.045 13.7 0.1 0.45 10.5 0.1 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat DUF4218 PF13960.6 EIM79771.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1258 PF06869.12 EIM79771.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) CDC45 PF02724.14 EIM79773.1 - 0.1 10.8 28.7 0.19 10.0 28.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EIM79773.1 - 0.3 9.3 46.6 0.46 8.6 46.6 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 EIM79773.1 - 0.45 10.5 27.0 1.1 9.2 27.0 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mpp10 PF04006.12 EIM79773.1 - 0.47 8.8 32.3 0.82 8.0 32.3 1.4 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 EIM79773.1 - 1.1 8.5 40.3 2.3 7.5 40.3 1.4 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 EIM79773.1 - 2.1 8.1 12.2 3.8 7.3 12.2 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Rrn6 PF10214.9 EIM79773.1 - 3.3 6.1 12.3 3 6.2 10.2 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor RNA_pol_Rpc4 PF05132.14 EIM79773.1 - 7 7.1 9.5 18 5.7 9.5 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 EIM79773.1 - 8.8 5.6 49.9 16 4.8 49.9 1.3 1 0 0 1 1 1 0 SDA1 JmjC PF02373.22 EIM79778.1 - 8.1e-09 35.9 0.0 6.7e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EIM79778.1 - 0.0063 16.2 0.1 0.012 15.4 0.1 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EIM79778.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain F-box PF00646.33 EIM79779.1 - 0.00054 19.8 1.5 0.0018 18.1 0.5 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM79779.1 - 0.024 14.5 0.4 0.024 14.5 0.4 2.4 3 0 0 3 3 3 0 F-box-like DUF1729 PF08354.10 EIM79784.1 - 3.9e-108 361.5 0.4 2.7e-90 302.8 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1729) FAS_meander PF17951.1 EIM79784.1 - 6.4e-22 77.9 0.0 2.3e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain PspA_IM30 PF04012.12 EIM79785.1 - 0.071 12.7 0.1 0.097 12.2 0.1 1.1 1 0 0 1 1 1 0 PspA/IM30 family LacI PF00356.21 EIM79785.1 - 0.17 11.7 0.0 6.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family SnoaL_2 PF12680.7 EIM79786.1 - 2.2e-06 28.2 0.1 4.5e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain PA14 PF07691.12 EIM79787.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 PA14 domain BACON PF13004.7 EIM79787.1 - 0.078 13.0 7.0 0.041 13.9 5.0 1.6 1 1 0 1 1 1 0 Putative binding domain, N-terminal SDA1 PF05285.12 EIM79788.1 - 2.5 7.4 19.7 1.1 8.7 0.6 2.1 2 0 0 2 2 2 0 SDA1 AbiJ_NTD5 PF18865.1 EIM79789.1 - 0.072 12.9 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Chromo PF00385.24 EIM79790.1 - 1.9e-07 30.8 0.0 2.6e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EIM79790.1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain GATA PF00320.27 EIM79791.1 - 9.8e-20 69.9 15.9 1.5e-13 50.0 3.5 2.3 2 0 0 2 2 2 2 GATA zinc finger zinc_ribbon_9 PF14369.6 EIM79791.1 - 0.033 14.4 0.9 0.1 12.9 0.9 1.8 1 0 0 1 1 1 0 zinc-ribbon Zn-ribbon_8 PF09723.10 EIM79791.1 - 0.077 13.1 1.6 0.59 10.3 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EIM79791.1 - 0.39 10.3 9.7 0.1 12.1 2.6 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RRN7 PF11781.8 EIM79791.1 - 0.67 9.7 0.0 0.67 9.7 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pkinase_fungal PF17667.1 EIM79792.1 - 9.3e-77 258.5 0.1 1.3e-76 258.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Importin_rep_4 PF18808.1 EIM79793.1 - 2e-07 31.2 0.0 4.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Importin repeat HEAT PF02985.22 EIM79793.1 - 0.0024 18.0 0.0 20 5.8 0.0 4.4 3 1 1 4 4 4 1 HEAT repeat Utp12 PF04003.12 EIM79793.1 - 0.059 13.7 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family Npa1 PF11707.8 EIM79793.1 - 0.11 11.8 0.0 4.7 6.5 0.0 2.5 2 1 0 2 2 2 0 Ribosome 60S biogenesis N-terminal Glyco_hydro_18 PF00704.28 EIM79794.1 - 2.3e-48 165.6 0.7 3.3e-48 165.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 EIM79794.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF4185 PF13810.6 EIM79795.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Mod_r PF07200.13 EIM79795.1 - 0.017 15.3 1.7 0.017 15.3 1.7 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CASP_C PF08172.12 EIM79795.1 - 0.037 13.4 5.0 0.06 12.7 5.0 1.3 1 0 0 1 1 1 0 CASP C terminal SOGA PF11365.8 EIM79795.1 - 1.4 10.0 13.5 1.4 10.1 6.5 2.2 2 0 0 2 2 2 0 Protein SOGA ZapB PF06005.12 EIM79795.1 - 4 8.0 13.7 1.1 9.7 1.6 2.9 2 1 1 3 3 3 0 Cell division protein ZapB ZapB PF06005.12 EIM79796.1 - 0.0082 16.6 1.4 0.1 13.0 0.7 2.3 2 0 0 2 2 2 1 Cell division protein ZapB DUF2353 PF09789.9 EIM79796.1 - 0.049 13.0 3.5 0.17 11.2 0.9 2.1 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) LRRFIP PF09738.9 EIM79796.1 - 0.25 10.8 7.2 2.6 7.5 0.1 2.2 2 0 0 2 2 2 0 LRRFIP family G-alpha PF00503.20 EIM79797.1 - 1.2e-30 106.9 0.0 1.4e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Ribosomal_L7Ae PF01248.26 EIM79800.1 - 1.3e-13 50.5 0.3 2.2e-13 49.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EIM79800.1 - 0.17 10.8 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) APH PF01636.23 EIM79801.1 - 7.3e-17 62.1 0.7 1e-16 61.6 0.7 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM79801.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EIM79801.1 - 0.039 13.3 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydant_A_N PF05378.13 EIM79803.1 - 9.6e-08 31.9 1.8 1.2e-07 31.7 0.4 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EIM79803.1 - 1.1e-07 31.4 0.1 3.9e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Zn_clus PF00172.18 EIM79804.1 - 3.9e-06 26.9 7.1 7.8e-06 25.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIM79804.1 - 0.001 18.2 0.4 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain COesterase PF00135.28 EIM79805.1 - 1.1e-07 31.1 0.0 1.4e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Retrotran_gag_2 PF14223.6 EIM79809.1 - 2.2e-11 43.6 0.1 3.3e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF444 PF04285.12 EIM79809.1 - 0.35 9.9 9.8 0.53 9.3 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) eIF-3_zeta PF05091.12 EIM79809.1 - 0.56 9.1 12.6 0.76 8.7 12.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 EIM79809.1 - 0.58 9.7 17.1 0.93 9.1 17.1 1.3 1 0 0 1 1 1 0 Spt20 family Raftlin PF15250.6 EIM79809.1 - 4 6.1 7.6 5.8 5.5 7.6 1.2 1 0 0 1 1 1 0 Raftlin KDZ PF18758.1 EIM79812.1 - 1.5e-53 181.7 0.1 2.2e-53 181.2 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM79812.1 - 1e-31 109.2 0.0 4e-31 107.3 0.0 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM79812.1 - 0.00016 21.8 0.0 0.00043 20.4 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Retrotrans_gag PF03732.17 EIM79814.1 - 0.33 11.3 2.5 1.2 9.4 2.5 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein MULE PF10551.9 EIM79815.1 - 7.3e-10 39.1 0.0 4.9e-09 36.5 0.0 2.4 2 1 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 EIM79815.1 - 0.01 15.5 1.0 0.01 15.5 1.0 2.4 3 0 0 3 3 3 0 SWIM zinc finger GATase_5 PF13507.6 EIM79816.1 - 4.8e-80 268.4 0.0 7.3e-80 267.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EIM79816.1 - 3.8e-38 131.1 1.2 7.5e-23 81.4 0.8 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 EIM79816.1 - 1.1e-21 77.1 0.0 2.3e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain FGAR-AT_N PF18076.1 EIM79816.1 - 2.6e-05 24.2 0.2 0.00048 20.1 0.0 2.6 3 0 0 3 3 3 1 Formylglycinamide ribonucleotide amidotransferase N-terminal Fungal_trans PF04082.18 EIM79818.1 - 3.3e-10 39.4 1.5 5.1e-10 38.8 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM79818.1 - 3.5e-05 23.8 4.6 6.9e-05 22.9 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CxC2 PF18803.1 EIM79821.1 - 7.1e-10 39.0 0.1 1.1e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EIM79822.1 - 2.6e-23 82.1 6.9 2.6e-23 82.1 6.9 2.5 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CPT PF07931.12 EIM79822.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_1 PF00515.28 EIM79824.1 - 0.005 16.6 0.0 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM79824.1 - 0.12 12.5 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM79824.1 - 0.14 12.4 0.0 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Collagen PF01391.18 EIM79825.1 - 0.6 9.9 10.5 1.4 8.7 10.5 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PUF PF00806.19 EIM79826.1 - 1.1e-24 84.7 3.1 5.2e-08 32.2 0.1 4.4 3 1 1 4 4 4 4 Pumilio-family RNA binding repeat RasGAP PF00616.19 EIM79827.1 - 9.9e-41 139.7 0.1 3.1e-37 128.3 0.0 2.7 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF2279 PF10043.9 EIM79827.1 - 0.011 16.5 0.0 0.34 11.7 0.0 2.9 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) NmrA PF05368.13 EIM79830.1 - 1.8e-20 73.5 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM79830.1 - 5.9e-11 42.6 0.0 8.9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DNA_topoisoIV PF00521.20 EIM79831.1 - 0.0008 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A HATPase_c PF02518.26 EIM79831.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_tran PF00005.27 EIM79832.1 - 2.9e-05 24.6 0.0 3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Pkinase_fungal PF17667.1 EIM79834.1 - 9.9e-10 37.8 0.3 1.1e-09 37.7 0.3 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM79834.1 - 0.0027 17.7 0.3 0.0038 17.2 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phasin PF05597.11 EIM79835.1 - 0.028 14.4 0.3 0.053 13.5 0.3 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DDHD PF02862.17 EIM79835.1 - 0.048 13.8 1.4 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 DDHD domain Cauli_VI PF01693.16 EIM79836.1 - 1.4e-15 57.3 5.8 4.6e-06 26.8 0.3 3.7 3 1 1 4 4 4 3 Caulimovirus viroplasmin 2OG-FeII_Oxy_3 PF13640.6 EIM79838.1 - 0.00019 22.2 0.0 0.0009 20.1 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily KDZ PF18758.1 EIM79839.1 - 6e-54 183.0 0.0 2.3e-53 181.1 0.0 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM79839.1 - 1.1e-39 134.9 0.0 2.1e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM79839.1 - 6.5e-07 29.5 0.2 4.1e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EIM79839.1 - 0.005 16.7 0.1 0.005 16.7 0.1 1.9 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Clathrin_H_link PF13838.6 EIM79839.1 - 0.017 15.0 0.4 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Clathrin-H-link zf-B_box PF00643.24 EIM79839.1 - 0.13 12.5 2.8 0.35 11.0 2.8 1.7 1 0 0 1 1 1 0 B-box zinc finger PIRT PF15099.6 EIM79840.1 - 0.0043 16.6 1.3 0.0075 15.9 1.3 1.4 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family CxC2 PF18803.1 EIM79842.1 - 8e-20 71.0 0.1 8e-20 71.0 0.1 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases SNF2_N PF00176.23 EIM79844.1 - 0.00049 18.9 0.3 0.00074 18.3 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SR-25 PF10500.9 EIM79844.1 - 0.015 14.9 5.2 0.029 14.0 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chromo PF00385.24 EIM79844.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.14 EIM79845.1 - 2.4e-11 43.3 0.0 2.5e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.16 EIM79848.1 - 9.6e-14 51.1 2.0 1e-13 50.9 2.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79848.1 - 7.1e-11 41.6 1.2 8.6e-11 41.3 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EIM79848.1 - 0.00098 17.7 0.1 0.0016 16.9 0.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Seryl_tRNA_N PF02403.22 EIM79852.1 - 0.0094 16.2 1.0 0.023 15.0 1.0 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain WXG100 PF06013.12 EIM79852.1 - 0.069 13.4 0.2 0.18 12.0 0.1 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG ATG16 PF08614.11 EIM79852.1 - 0.078 13.2 0.5 0.078 13.2 0.5 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EIM79852.1 - 0.11 11.4 0.3 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EIM79852.1 - 0.11 12.5 0.5 0.35 11.0 0.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein VASP_tetra PF08776.11 EIM79852.1 - 1.5 8.5 4.7 37 4.0 0.7 3.2 3 0 0 3 3 3 0 VASP tetramerisation domain APG6_N PF17675.1 EIM79854.1 - 0.04 14.4 0.9 0.072 13.6 0.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 EIM79854.1 - 0.055 13.3 1.0 0.088 12.6 1.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Ribonucleas_3_2 PF11469.8 EIM79854.1 - 0.06 13.8 0.2 0.11 13.0 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease III Rx_N PF18052.1 EIM79854.1 - 0.065 13.5 1.2 0.14 12.5 1.2 1.5 1 0 0 1 1 1 0 Rx N-terminal domain Spc7 PF08317.11 EIM79854.1 - 0.08 11.8 0.9 0.12 11.2 0.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ECM11 PF15463.6 EIM79854.1 - 0.091 13.3 1.6 0.17 12.4 1.6 1.4 1 0 0 1 1 1 0 Extracellular mutant protein 11 Focal_AT PF03623.13 EIM79854.1 - 0.16 12.0 0.2 0.34 10.9 0.2 1.5 1 0 0 1 1 1 0 Focal adhesion targeting region Lebercilin PF15619.6 EIM79854.1 - 0.17 11.6 1.5 0.27 10.9 1.5 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease WD40_alt PF14077.6 EIM79854.1 - 1.3 8.9 4.7 1.3 9.0 1.1 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif F-box PF00646.33 EIM79856.1 - 0.053 13.4 0.1 13 5.8 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EIM79856.1 - 0.058 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like DDE_3 PF13358.6 EIM79857.1 - 2.7e-06 27.2 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease NR_Repeat PF14046.6 EIM79857.1 - 0.065 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor repeat Inv-AAD PF18785.1 EIM79857.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Vert_IL3-reg_TF PF06529.11 EIM79857.1 - 0.24 10.5 0.2 0.32 10.1 0.2 1.2 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor DUF596 PF04591.12 EIM79858.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF596 CT_A_B PF02626.15 EIM79859.1 - 3.1e-13 49.9 0.0 3.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B KDZ PF18758.1 EIM79861.1 - 2.7e-60 203.8 0.0 3.6e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM79861.1 - 7.8e-33 112.8 0.1 2.2e-32 111.4 0.1 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM79861.1 - 1.5e-06 28.3 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EIM79861.1 - 0.048 13.5 0.0 0.048 13.5 0.0 1.9 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 EIM79861.1 - 0.81 9.9 13.5 0.035 14.3 7.3 2.0 2 0 0 2 2 2 0 B-box zinc finger Cauli_VI PF01693.16 EIM79865.1 - 6e-11 42.5 0.0 3.1e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Caulimovirus viroplasmin P5-ATPase PF12409.8 EIM79867.1 - 0.18 11.9 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter EF-hand_1 PF00036.32 EIM79868.1 - 0.41 10.3 0.1 0.41 10.3 0.1 2.8 3 0 0 3 3 3 0 EF hand F-box-like PF12937.7 EIM79869.1 - 0.00079 19.3 0.5 0.0037 17.1 0.5 2.2 1 1 0 1 1 1 1 F-box-like Elongin_A PF06881.11 EIM79869.1 - 0.0051 17.3 0.1 0.035 14.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CCD48 PF15799.5 EIM79870.1 - 0.01 14.2 6.4 0.013 13.9 6.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Peptidase_M32 PF02074.15 EIM79870.1 - 0.058 12.2 1.9 0.068 11.9 1.9 1.0 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase HisKA_3 PF07730.13 EIM79870.1 - 0.47 11.0 10.1 0.74 10.4 5.5 2.3 1 1 1 2 2 2 0 Histidine kinase VIR_N PF15912.5 EIM79870.1 - 1 8.9 6.7 1.4 8.4 6.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal HEAT PF02985.22 EIM79871.1 - 3.7e-07 29.9 0.2 1.6e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EIM79871.1 - 0.00061 20.3 0.0 0.82 10.3 0.0 2.3 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EIM79871.1 - 0.0023 18.4 0.0 3.9 8.1 0.1 2.6 2 0 0 2 2 2 2 HEAT-like repeat Cnd1 PF12717.7 EIM79871.1 - 0.027 14.5 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIM79871.1 - 0.042 14.3 0.1 0.091 13.2 0.0 1.6 2 0 0 2 2 2 0 HEAT repeats COesterase PF00135.28 EIM79872.1 - 1.2e-11 44.2 0.0 1.5e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Fungal_trans PF04082.18 EIM79873.1 - 3.4e-10 39.4 1.0 5.7e-10 38.7 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM79873.1 - 9.2e-07 28.9 7.2 2e-06 27.8 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 EIM79875.1 - 3e-71 239.6 2.8 7.7e-71 238.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Utp14 PF04615.13 EIM79875.1 - 3.1 6.2 6.2 4.1 5.9 6.2 1.0 1 0 0 1 1 1 0 Utp14 protein SOG2 PF10428.9 EIM79875.1 - 4.3 6.4 21.0 5.4 6.1 21.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EIM79875.1 - 9.5 6.0 11.0 13 5.6 11.0 1.1 1 0 0 1 1 1 0 SPX domain MFS_1 PF07690.16 EIM79876.1 - 3.2e-23 82.2 46.2 5.2e-23 81.5 46.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3981 PF13139.6 EIM79876.1 - 0.013 15.8 0.2 0.044 14.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) Rnf-Nqr PF02508.14 EIM79877.1 - 0.015 15.2 1.4 0.019 14.9 1.4 1.1 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein DUF1475 PF07343.11 EIM79877.1 - 0.042 13.6 0.6 0.054 13.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) Pyr_redox_3 PF13738.6 EIM79879.1 - 1.2e-20 74.0 0.0 3.1e-18 66.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM79879.1 - 2.4e-20 73.0 0.0 1.8e-16 60.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIM79879.1 - 6.7e-16 57.8 0.0 1e-14 53.9 0.0 2.4 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EIM79879.1 - 2e-13 50.2 0.0 1.2e-10 41.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EIM79879.1 - 1.3e-11 44.9 0.9 0.00024 21.6 0.2 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM79879.1 - 2.4e-10 40.2 0.4 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM79879.1 - 4.6e-08 33.2 0.2 0.00012 22.2 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 EIM79879.1 - 8e-07 28.6 0.0 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EIM79879.1 - 4.3e-06 26.1 0.9 0.1 11.7 0.0 3.2 4 0 0 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.17 EIM79879.1 - 0.00027 20.3 0.3 0.059 12.6 0.2 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EIM79879.1 - 0.0003 19.9 0.1 0.076 12.0 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.21 EIM79879.1 - 0.00045 19.7 0.1 0.22 10.9 0.0 2.7 3 0 0 3 3 3 1 ThiF family DAO PF01266.24 EIM79879.1 - 0.00071 19.3 0.0 2.4 7.6 0.0 3.4 4 0 0 4 4 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM79879.1 - 0.00082 18.6 0.2 0.14 11.2 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 EIM79879.1 - 0.0012 19.0 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EIM79879.1 - 0.0016 18.8 0.0 0.22 12.0 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EIM79879.1 - 0.0016 18.3 0.7 0.012 15.6 0.1 2.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EIM79879.1 - 0.0017 17.1 0.0 0.084 11.6 0.0 2.6 2 0 0 2 2 2 1 HI0933-like protein IlvN PF07991.12 EIM79879.1 - 0.0061 16.1 0.6 0.012 15.1 0.1 1.7 2 0 0 2 2 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EIM79879.1 - 0.011 15.9 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain ELFV_dehydrog PF00208.21 EIM79879.1 - 0.017 14.9 0.3 0.028 14.1 0.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 EIM79879.1 - 0.039 13.2 0.1 3.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EIM79879.1 - 0.067 13.2 0.3 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 EIM79879.1 - 0.073 13.6 0.0 17 5.9 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_9 PF13454.6 EIM79879.1 - 0.13 12.2 0.6 7 6.6 0.1 3.0 3 1 1 4 4 4 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 EIM79879.1 - 0.19 12.3 0.0 24 5.6 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.7 EIM79879.1 - 0.24 10.7 0.4 4 6.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Papilloma_E5 PF03025.14 EIM79880.1 - 0.38 10.9 10.3 1.3 9.2 1.7 2.8 1 1 1 2 2 2 0 Papillomavirus E5 MFS_1 PF07690.16 EIM79881.1 - 5.6e-22 78.1 37.4 1.7e-21 76.6 26.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79881.1 - 5.6e-13 48.6 25.0 2.6e-11 43.1 25.0 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter Pneumo_M2 PF07380.11 EIM79881.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Pneumovirus M2 protein FAD_binding_3 PF01494.19 EIM79882.1 - 1e-53 182.9 0.0 1.4e-53 182.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EIM79882.1 - 0.061 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EB PF01683.18 EIM79883.1 - 0.0013 19.0 18.9 5.1 7.5 9.0 4.9 2 1 2 4 4 4 2 EB module Defensin_beta_2 PF13841.6 EIM79883.1 - 0.13 12.8 2.6 0.45 11.0 1.2 2.8 2 0 0 2 2 2 0 Beta defensin Dickkopf_N PF04706.12 EIM79883.1 - 1.1 9.8 28.1 3.3 8.3 1.8 4.8 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Form_Nir_trans PF01226.17 EIM79884.1 - 1.9e-69 233.6 13.4 2.1e-69 233.5 13.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Tannase PF07519.11 EIM79885.1 - 1.7e-83 281.2 0.0 3.8e-83 280.0 0.0 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EIM79885.1 - 0.15 11.3 0.1 2.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_C14 PF00656.22 EIM79886.1 - 1.9e-14 54.3 0.0 4.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Caspase domain MCM PF00493.23 EIM79888.1 - 2.4e-99 331.0 0.0 3.5e-99 330.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIM79888.1 - 7.6e-37 126.0 0.0 1.3e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EIM79888.1 - 5.8e-30 104.6 28.5 9.9e-30 103.8 26.3 2.4 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EIM79888.1 - 2.7e-24 85.4 0.5 1.1e-23 83.5 0.5 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIM79888.1 - 3e-12 47.0 0.1 8.7e-12 45.6 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIM79888.1 - 1.2e-07 31.4 0.0 3.5e-06 26.6 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIM79888.1 - 5.8e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EIM79888.1 - 0.00092 19.1 0.1 0.011 15.5 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SelR PF01641.18 EIM79888.1 - 0.0013 18.8 0.2 0.54 10.3 0.1 2.4 2 0 0 2 2 2 2 SelR domain Sigma54_activat PF00158.26 EIM79888.1 - 0.0022 17.7 0.1 0.017 14.8 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 EIM79888.1 - 0.024 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ank_4 PF13637.6 EIM79889.1 - 0.024 15.2 0.1 0.07 13.7 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Methyltransf_3 PF01596.17 EIM79889.1 - 0.024 13.8 0.1 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase Ank_3 PF13606.6 EIM79889.1 - 0.13 12.9 0.0 0.49 11.1 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat adh_short PF00106.25 EIM79890.1 - 2.7e-37 128.1 0.0 4.7e-37 127.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79890.1 - 8.4e-24 84.4 0.0 2e-23 83.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79890.1 - 1.6e-08 34.7 0.2 2.8e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EIM79890.1 - 0.11 12.4 0.4 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 EIM79891.1 - 3.7e-37 127.7 0.1 1e-36 126.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79891.1 - 8.3e-25 87.7 0.2 2.9e-24 85.9 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79891.1 - 5.2e-09 36.3 0.8 2.5e-08 34.0 0.2 2.0 2 1 1 3 3 3 1 KR domain YjeF_N PF03853.15 EIM79891.1 - 0.0083 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus adh_short PF00106.25 EIM79892.1 - 1.5e-37 129.0 0.1 3.3e-37 127.8 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79892.1 - 1.4e-25 90.2 0.4 4.1e-25 88.7 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79892.1 - 1e-07 32.0 0.1 1.8e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EIM79892.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Ferrochelatase PF00762.19 EIM79892.1 - 0.03 13.4 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase RRM_2 PF04059.12 EIM79893.1 - 3.3e-32 110.5 0.3 4.1e-32 110.3 0.3 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EIM79893.1 - 9.2e-05 22.2 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EIM79893.1 - 0.043 14.0 0.1 0.18 12.0 0.1 1.9 1 1 1 2 2 2 0 BRCA1-associated protein 2 PHM7_cyt PF14703.6 EIM79893.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF4714 PF15833.5 EIM79895.1 - 0.066 13.2 0.5 1.4 8.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4714) adh_short PF00106.25 EIM79896.1 - 6e-38 130.3 0.1 7.7e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79896.1 - 6.7e-28 97.8 0.0 8.2e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79896.1 - 1.7e-10 41.1 0.1 2.5e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Ferrochelatase PF00762.19 EIM79896.1 - 0.0067 15.5 0.0 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase YjeF_N PF03853.15 EIM79896.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short PF00106.25 EIM79897.1 - 1.5e-37 128.9 0.0 3.5e-37 127.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79897.1 - 1.1e-26 93.9 0.1 2.7e-26 92.6 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79897.1 - 1.1e-08 35.2 1.1 3.9e-08 33.4 1.1 1.8 1 1 0 1 1 1 1 KR domain Ferrochelatase PF00762.19 EIM79897.1 - 0.0019 17.3 0.0 0.0026 16.9 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase NAD_binding_10 PF13460.6 EIM79897.1 - 0.026 14.4 0.4 0.041 13.8 0.4 1.3 1 0 0 1 1 1 0 NAD(P)H-binding SNase PF00565.17 EIM79898.1 - 1.1e-60 202.8 1.5 8.2e-21 74.5 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EIM79898.1 - 5.9e-19 68.3 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 EIM79898.1 - 0.01 16.3 1.0 0.24 11.9 0.0 3.4 4 0 0 4 4 4 0 Agenet domain MutL_C PF08676.11 EIM79900.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 MutL C terminal dimerisation domain TolA_bind_tri PF16331.5 EIM79901.1 - 0.56 10.3 7.9 2.5 8.2 3.1 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation ATG16 PF08614.11 EIM79901.1 - 2 8.6 23.7 0.12 12.5 16.7 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 EIM79901.1 - 4.5 5.1 6.7 8.5 4.2 6.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MIF4G PF02854.19 EIM79903.1 - 6.6e-47 159.9 0.0 5.6e-28 98.0 0.0 3.6 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EIM79903.1 - 5.2e-31 108.2 0.3 5.2e-31 108.2 0.3 3.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Na_trans_assoc PF06512.13 EIM79903.1 - 0.11 12.7 10.0 0.057 13.7 2.0 2.9 2 1 0 2 2 2 0 Sodium ion transport-associated MecA PF05389.12 EIM79903.1 - 2.7 7.5 9.1 11 5.6 4.3 3.3 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) adh_short PF00106.25 EIM79904.1 - 8.8e-34 116.7 0.0 2.5e-33 115.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM79904.1 - 5.2e-22 78.5 0.0 1.5e-21 77.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM79904.1 - 1.1e-06 28.7 0.0 4.1e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 KR domain Ferrochelatase PF00762.19 EIM79904.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase F-box-like PF12937.7 EIM79905.1 - 1.6e-07 31.1 1.5 5.3e-07 29.4 1.5 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM79905.1 - 0.12 12.3 3.2 13 5.8 0.1 3.5 3 0 0 3 3 3 0 F-box domain Zn_clus PF00172.18 EIM79906.1 - 0.00013 22.0 32.5 0.0026 17.8 12.0 3.3 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S6 PF01250.17 EIM79907.1 - 2.4e-22 79.0 0.0 2.8e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 Hydrolase PF00702.26 EIM79908.1 - 2.8e-08 34.3 0.0 4.8e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EIM79908.1 - 5.8e-08 33.0 0.0 1.4e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PRIMA1 PF16101.5 EIM79908.1 - 0.029 14.4 0.7 0.047 13.7 0.7 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3128 PF11326.8 EIM79909.1 - 3.5e-21 75.4 1.7 3.5e-21 75.4 1.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Acetyltransf_10 PF13673.7 EIM79910.1 - 2.2e-08 34.1 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM79910.1 - 1.4e-07 31.9 0.0 2.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM79910.1 - 2.1e-07 30.8 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EIM79910.1 - 6.1e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EIM79910.1 - 2.1e-06 27.8 0.0 0.00064 19.8 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain PanZ PF12568.8 EIM79910.1 - 0.0019 17.9 0.1 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EIM79910.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-TRM13_CCCH PF11722.8 EIM79910.1 - 0.089 12.6 0.8 11 5.9 0.0 2.3 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein Acetyltransf_4 PF13420.7 EIM79910.1 - 0.19 11.9 0.0 0.78 9.9 0.0 2.0 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EIM79911.1 - 2.2e-44 151.8 39.6 2.3e-44 151.8 17.2 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79911.1 - 2.7e-10 39.7 8.4 2.7e-10 39.7 8.4 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EIM79911.1 - 2.4e-06 26.3 3.2 4.2e-06 25.5 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EIM79911.1 - 0.00028 19.6 7.7 0.0015 17.2 9.1 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 EIM79911.1 - 0.074 11.9 8.3 0.48 9.2 8.3 2.0 1 1 0 1 1 1 0 MFS_1 like family OATP PF03137.20 EIM79911.1 - 0.39 8.9 7.5 2.1 6.5 0.4 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DASH_Dad2 PF08654.10 EIM79912.1 - 3.7e-07 30.5 0.0 1e-06 29.1 0.0 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 Med14 PF08638.11 EIM79913.1 - 3.4e-69 232.1 0.1 6.2e-69 231.2 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 MFS_1 PF07690.16 EIM79914.1 - 3e-46 158.0 48.1 1.1e-45 156.2 33.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79914.1 - 4.3e-13 48.9 12.7 4.3e-13 48.9 12.7 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EIM79914.1 - 3.5e-05 22.4 6.7 5.3e-05 21.9 6.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1156 PF06634.12 EIM79914.1 - 0.097 12.8 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) CPP1-like PF11833.8 EIM79914.1 - 3.9 7.1 6.4 10 5.7 6.4 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_2 PF13347.6 EIM79914.1 - 6 5.3 26.0 0.097 11.2 9.0 4.0 4 1 1 5 5 5 0 MFS/sugar transport protein HEAT PF02985.22 EIM79915.1 - 2.6e-11 42.8 0.4 0.065 13.5 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 EIM79915.1 - 5.1e-07 30.0 0.0 0.074 13.5 0.0 3.4 2 1 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 EIM79915.1 - 1.3e-05 25.3 0.0 0.0053 16.8 0.0 3.1 1 1 3 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 EIM79915.1 - 0.0016 17.8 0.0 0.011 15.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Adaptin_N PF01602.20 EIM79915.1 - 0.0037 15.9 0.0 2.3 6.7 0.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 EIM79915.1 - 0.0058 17.1 3.8 2.4 8.7 0.1 4.5 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EIM79915.1 - 0.057 14.0 0.0 6.7 7.4 0.0 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Chromo PF00385.24 EIM79916.1 - 1.3e-09 37.8 1.7 2.6e-09 36.8 1.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4295 PF14128.6 EIM79916.1 - 0.038 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) Med12 PF09497.10 EIM79917.1 - 1.9e-25 88.9 0.5 1.4e-24 86.1 0.1 2.6 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EIM79917.1 - 0.0058 15.5 0.0 0.015 14.2 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain UCH PF00443.29 EIM79918.1 - 3.2e-09 36.7 0.0 4.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L13e PF01294.18 EIM79918.1 - 0.12 12.2 0.6 0.24 11.3 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein L13e RRM_1 PF00076.22 EIM79919.1 - 0.0032 17.2 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_3_Rpc31 PF11705.8 EIM79919.1 - 3.5 7.8 24.0 1.3 9.2 7.9 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cas_Csy2 PF09614.10 EIM79923.1 - 0.033 13.5 0.1 0.87 8.9 0.0 2.6 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Csy2) Glyco_hydro_79C PF16862.5 EIM79925.1 - 2.8e-16 60.3 3.2 5.4e-16 59.4 3.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Ank PF00023.30 EIM79926.1 - 3.4e-15 55.7 2.3 4.1e-07 30.2 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EIM79926.1 - 2e-13 50.7 0.2 7.1e-06 26.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM79926.1 - 8.3e-13 48.6 0.3 0.00017 22.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM79926.1 - 1.9e-12 46.2 0.7 6.8e-05 23.0 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EIM79926.1 - 8.9e-11 41.8 0.4 3.3e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SelP_N PF04592.14 EIM79926.1 - 0.15 11.4 11.6 0.18 11.2 11.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1576 PF07613.11 EIM79928.1 - 0.06 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) G-alpha PF00503.20 EIM79929.1 - 4.3e-113 378.1 0.0 5.1e-113 377.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM79929.1 - 4.2e-10 39.3 0.0 5.4e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EIM79929.1 - 0.0014 18.8 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EIM79929.1 - 0.039 13.2 0.4 0.82 8.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 EIM79929.1 - 0.04 13.3 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 EIM79929.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 EIM79929.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EIM79929.1 - 0.13 11.7 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EIM79929.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MFS_1 PF07690.16 EIM79930.1 - 1.3e-44 152.6 42.4 1.3e-44 152.6 42.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79930.1 - 8.7e-12 44.6 23.8 1.1e-10 40.9 23.8 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EIM79930.1 - 1.1e-05 24.1 4.7 1.1e-05 24.1 4.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 EIM79931.1 - 2.6e-07 30.4 0.5 1.3e-06 28.2 0.5 2.2 1 1 0 1 1 1 1 F-box-like CTXphi_pIII-N1 PF16710.5 EIM79932.1 - 0.073 13.2 0.2 0.092 12.9 0.2 1.4 1 1 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Transp_cyt_pur PF02133.15 EIM79933.1 - 3.1e-26 92.2 31.5 3.8e-26 91.9 31.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.8 EIM79933.1 - 6.1 6.7 10.9 3 7.8 7.5 2.1 2 0 0 2 2 2 0 Conserved membrane protein YqhR Glyco_hydro_44 PF12891.7 EIM79935.1 - 5.3e-58 196.7 2.7 8.3e-58 196.1 2.7 1.3 1 0 0 1 1 1 1 Glycoside hydrolase family 44 F-box-like PF12937.7 EIM79936.1 - 4.6e-08 32.8 0.6 1.6e-07 31.1 0.6 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM79937.1 - 2.2e-06 27.4 2.1 5.9e-06 26.1 1.3 2.2 2 1 0 2 2 2 1 F-box-like Fungal_trans PF04082.18 EIM79938.1 - 1.3e-11 44.0 0.0 3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM79938.1 - 1.9e-07 31.0 8.0 4.7e-07 29.8 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EIM79938.1 - 1.5e-06 28.4 9.6 0.0099 16.3 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM79938.1 - 2.5e-06 27.7 7.5 3.9e-05 23.9 2.2 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM79938.1 - 0.0059 17.4 15.1 0.017 15.9 2.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger PSI_integrin PF17205.3 EIM79938.1 - 0.0097 15.6 0.5 0.0097 15.6 0.5 2.2 2 0 0 2 2 2 1 Integrin plexin domain zf-Di19 PF05605.12 EIM79938.1 - 0.36 11.2 2.8 0.76 10.1 2.8 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EIM79938.1 - 7.4 7.1 6.7 14 6.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NAM-associated PF14303.6 EIM79940.1 - 0.14 12.8 10.9 0.22 12.3 10.9 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF2894 PF11445.8 EIM79940.1 - 4.2 7.8 11.0 9.1 6.7 11.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) CDC45 PF02724.14 EIM79941.1 - 2.2 6.5 6.1 3.2 5.9 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 EIM79941.1 - 4.2 7.3 10.7 10 6.1 10.7 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SpoIIIAH PF12685.7 EIM79941.1 - 9.9 5.9 7.5 18 5.1 7.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein S1-P1_nuclease PF02265.16 EIM79942.1 - 1e-65 222.1 0.0 1.2e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease AA_permease_2 PF13520.6 EIM79943.1 - 5e-74 249.6 49.1 6.2e-74 249.3 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM79943.1 - 2.4e-19 69.3 42.7 3.5e-19 68.8 42.7 1.2 1 0 0 1 1 1 1 Amino acid permease BTB PF00651.31 EIM79944.1 - 0.022 15.0 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain CSG2 PF16965.5 EIM79945.1 - 0.0038 16.2 0.1 0.0062 15.5 0.1 1.3 1 0 0 1 1 1 1 Ceramide synthase regulator Apolipoprotein PF01442.18 EIM79946.1 - 3.2e-06 27.1 17.7 5.1e-06 26.5 17.7 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EIM79946.1 - 0.0019 18.7 24.2 0.0021 18.6 3.3 3.6 1 1 3 4 4 4 1 Bacterial protein of unknown function (DUF883) DUF3810 PF12725.7 EIM79946.1 - 0.022 14.1 0.3 0.038 13.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) YchF-GTPase_C PF06071.13 EIM79946.1 - 0.03 14.5 0.5 0.03 14.5 0.5 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF933) DUF4366 PF14283.6 EIM79946.1 - 0.062 13.3 2.8 0.19 11.8 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DUF2681 PF10883.8 EIM79946.1 - 0.097 13.1 0.1 0.097 13.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4131 PF13567.6 EIM79946.1 - 0.18 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YtxH PF12732.7 EIM79946.1 - 0.26 11.8 27.8 2.7 8.6 1.9 4.0 1 1 1 2 2 2 0 YtxH-like protein His_Phos_1 PF00300.22 EIM79946.1 - 0.97 9.1 9.6 4.5 6.9 0.3 2.7 1 1 2 3 3 3 0 Histidine phosphatase superfamily (branch 1) ApoLp-III PF07464.11 EIM79946.1 - 1.8 8.6 13.7 21 5.2 11.3 2.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SOAR PF16533.5 EIM79946.1 - 1.9 8.5 9.9 1 9.4 5.0 2.8 1 1 2 3 3 3 0 STIM1 Orai1-activating region DUF2959 PF11172.8 EIM79946.1 - 3.8 7.6 14.8 6 7.0 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Lant_dehydr_C PF14028.6 EIM79946.1 - 7.5 6.0 10.4 2.5 7.5 6.5 1.9 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Peptidase_C14 PF00656.22 EIM79947.1 - 3.2e-17 63.3 0.0 5.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM79947.1 - 0.00067 19.2 0.0 0.0037 16.7 0.0 2.2 2 1 0 2 2 2 1 CHAT domain FrhB_FdhB_N PF04422.13 EIM79947.1 - 0.015 15.5 0.0 0.34 11.1 0.0 2.4 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Peptidase_C14 PF00656.22 EIM79948.1 - 2.2e-15 57.3 0.0 5.5e-15 56.0 0.0 1.5 2 0 0 2 2 2 1 Caspase domain Peptidase_C14 PF00656.22 EIM79949.1 - 1.9e-19 70.6 0.0 3.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM79949.1 - 0.00018 21.1 0.0 0.00084 18.8 0.0 2.1 3 0 0 3 3 3 1 CHAT domain AAA_18 PF13238.6 EIM79950.1 - 3.2e-05 24.5 0.0 0.00021 21.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM79950.1 - 0.048 14.0 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 EIM79950.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EIM79950.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EIM79950.1 - 0.14 12.4 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EIM79950.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI APH PF01636.23 EIM79951.1 - 1.7e-08 34.7 0.0 0.00088 19.3 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 EIM79951.1 - 0.00018 20.5 0.0 0.06 12.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) FAD_binding_2 PF00890.24 EIM79954.1 - 3.3e-88 296.6 1.0 3.3e-88 296.6 1.0 1.3 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 EIM79954.1 - 2.4e-23 82.0 0.0 7.2e-23 80.5 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EIM79954.1 - 1.4e-13 51.2 1.6 6.2e-13 49.1 1.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM79954.1 - 2.2e-10 40.3 1.2 1.2e-08 34.5 0.7 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM79954.1 - 7.3e-10 38.9 0.6 4.2e-09 36.5 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EIM79954.1 - 1.4e-09 37.9 3.9 3.9e-09 36.4 3.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIM79954.1 - 2.3e-07 30.4 0.3 3.8e-07 29.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EIM79954.1 - 6.2e-07 28.8 3.3 0.00013 21.2 1.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 EIM79954.1 - 5.8e-06 25.3 7.0 0.00012 20.9 0.6 3.2 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 EIM79954.1 - 7.5e-05 22.1 4.1 0.053 12.8 1.2 2.7 3 0 0 3 3 3 2 Thi4 family Amino_oxidase PF01593.24 EIM79954.1 - 9.4e-05 21.9 1.7 0.0075 15.6 0.4 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EIM79954.1 - 0.00015 21.1 0.3 0.18 11.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM79954.1 - 0.00053 19.4 0.9 0.001 18.4 0.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EIM79954.1 - 0.0011 19.5 1.5 0.063 13.8 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM79954.1 - 0.003 17.5 0.8 1.5 8.8 0.3 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EIM79954.1 - 0.0079 15.3 0.2 0.051 12.6 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 EIM79954.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GET2 PF08690.10 EIM79954.1 - 0.074 12.7 1.6 0.12 12.0 1.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 GMC_oxred_N PF00732.19 EIM79954.1 - 0.3 10.4 3.2 0.5 9.7 0.0 2.5 3 0 0 3 3 3 0 GMC oxidoreductase Period_C PF12114.8 EIM79954.1 - 2.4 7.7 6.8 4 7.0 6.8 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Methyltransf_2 PF00891.18 EIM79956.1 - 7.5e-15 54.8 0.0 1.1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EIM79956.1 - 0.0029 17.2 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EIM79956.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Acyl-CoA_ox_N PF14749.6 EIM79956.1 - 0.19 12.3 0.1 0.33 11.5 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal GATA PF00320.27 EIM79957.1 - 1.9e-23 81.7 23.0 8.7e-16 57.2 3.1 2.4 2 0 0 2 2 2 2 GATA zinc finger eIF-5_eIF-2B PF01873.17 EIM79957.1 - 0.0025 17.7 3.3 0.45 10.4 0.1 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 EIM79957.1 - 0.0084 16.2 6.2 0.089 13.0 0.9 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRN7 PF11781.8 EIM79957.1 - 0.018 14.7 0.7 0.018 14.7 0.7 2.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_9 PF14369.6 EIM79957.1 - 0.028 14.7 0.4 0.028 14.7 0.4 2.5 2 1 0 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 EIM79957.1 - 0.072 13.2 9.6 0.15 12.2 0.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain OTT_1508_deam PF14441.6 EIM79957.1 - 0.94 9.5 0.1 0.94 9.5 0.1 2.9 3 0 0 3 3 3 0 OTT_1508-like deaminase TF_Zn_Ribbon PF08271.12 EIM79957.1 - 0.96 9.0 10.5 0.07 12.7 1.4 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.13 EIM79957.1 - 2.8 8.1 9.5 1.5 8.9 0.2 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like CHAT PF12770.7 EIM79959.1 - 9.8e-33 113.8 0.0 1.6e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_7 PF13176.6 EIM79959.1 - 0.011 15.7 0.0 0.41 10.8 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ComR_TPR PF18710.1 EIM79959.1 - 0.02 14.5 0.1 0.042 13.4 0.0 1.6 2 0 0 2 2 2 0 ComR tetratricopeptide TPR_8 PF13181.6 EIM79959.1 - 0.023 14.9 2.7 0.29 11.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Paz_1 PF18349.1 EIM79959.1 - 0.12 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 PAZ domain TPR_2 PF07719.17 EIM79959.1 - 3.4 8.0 5.3 19 5.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_M19 PF01244.21 EIM79960.1 - 1.4e-99 333.3 0.0 1.6e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) LptF_LptG PF03739.14 EIM79962.1 - 0.25 10.2 3.0 0.27 10.1 3.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Methyltransf_2 PF00891.18 EIM79963.1 - 5.9e-20 71.5 0.0 1.7e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 EIM79963.1 - 0.00025 20.7 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EIM79963.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_25 PF13649.6 EIM79963.1 - 0.044 14.5 0.0 0.087 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DprA_WH PF17782.1 EIM79963.1 - 0.12 12.5 0.2 7.3 6.8 0.0 2.8 2 0 0 2 2 2 0 DprA winged helix domain PrmA PF06325.13 EIM79963.1 - 0.19 11.1 0.2 14 4.9 0.5 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) HUN PF08729.10 EIM79964.1 - 0.032 14.2 1.6 0.056 13.5 1.6 1.3 1 0 0 1 1 1 0 HPC2 and ubinuclein domain Peptidase_M19 PF01244.21 EIM79965.1 - 1.5e-94 316.7 0.0 1.9e-94 316.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) ECH_1 PF00378.20 EIM79967.1 - 1.4e-83 280.1 0.1 1.7e-83 279.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIM79967.1 - 1.3e-35 123.5 0.2 1.6e-33 116.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase NTP_transferase PF00483.23 EIM79972.1 - 2e-40 138.9 0.0 7.4e-40 137.1 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EIM79972.1 - 8.5e-07 29.5 0.5 2.4e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 EIM79972.1 - 6.3e-05 22.9 0.5 0.00026 20.9 0.2 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase IspD PF01128.19 EIM79972.1 - 0.087 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CCDC92 PF14916.6 EIM79972.1 - 0.26 11.1 0.4 0.57 10.0 0.1 1.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DivIC PF04977.15 EIM79972.1 - 0.38 10.5 1.2 1.2 9.0 0.5 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 EIM79975.1 - 4 7.5 28.8 0.099 12.7 1.4 5.4 2 1 2 6 6 6 0 Protein of unknown function (DUF1664) COMMD1_N PF17221.3 EIM79975.1 - 7.5 6.9 11.4 0.69 10.2 0.7 3.3 2 2 1 3 3 3 0 COMMD1 N-terminal domain FlaC_arch PF05377.11 EIM79975.1 - 8.9 6.8 11.8 49 4.4 0.2 4.9 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) MyTH4 PF00784.17 EIM79976.1 - 8.3e-31 106.7 0.0 2.1e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 EIM79976.1 - 4.5e-28 98.0 0.0 7.4e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 EIM79976.1 - 4.3e-11 42.7 5.5 6.7e-05 22.9 4.1 2.5 2 0 0 2 2 2 2 WW domain HpcH_HpaI PF03328.14 EIM79977.1 - 1.4e-28 99.6 0.0 1.8e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 EIM79977.1 - 0.016 14.1 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain VWA_2 PF13519.6 EIM79979.1 - 0.023 15.3 0.3 0.079 13.6 0.1 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain DUF3175 PF11373.8 EIM79979.1 - 0.1 12.7 0.0 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) KNOX2 PF03791.13 EIM79979.1 - 0.11 12.0 0.4 0.36 10.4 0.1 2.0 2 0 0 2 2 2 0 KNOX2 domain GMC_oxred_C PF05199.13 EIM79982.1 - 5.6e-34 117.7 0.0 1e-33 116.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EIM79982.1 - 1.5e-33 116.4 0.0 2.4e-23 83.0 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM79982.1 - 0.00014 22.1 0.1 0.00032 20.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM79982.1 - 0.00072 18.7 0.2 0.0011 18.1 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM79982.1 - 0.001 18.3 0.4 0.0038 16.4 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EIM79982.1 - 0.0044 16.6 0.7 0.0095 15.6 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM79982.1 - 0.011 14.5 0.1 0.05 12.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 EIM79982.1 - 0.013 14.8 0.1 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM79982.1 - 0.046 13.0 0.2 0.091 12.0 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EIM79982.1 - 0.059 12.6 0.4 0.51 9.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM79982.1 - 0.22 10.3 0.1 0.37 9.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 EIM79984.1 - 2e-31 109.9 0.0 2.5e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase dsrm PF00035.26 EIM79986.1 - 8.6e-08 32.8 0.1 1.5e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EIM79986.1 - 3.4e-07 30.5 0.1 3.1e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIM79986.1 - 0.00062 20.4 0.0 0.002 18.7 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain DUF812 PF05667.11 EIM79988.1 - 0.0091 14.9 6.4 0.011 14.7 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ADIP PF11559.8 EIM79988.1 - 0.015 15.4 8.8 0.022 14.9 8.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 EIM79988.1 - 0.015 15.5 3.2 0.019 15.2 3.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 LXG PF04740.12 EIM79988.1 - 0.019 14.7 8.1 0.026 14.2 8.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily OmpH PF03938.14 EIM79988.1 - 0.022 15.1 12.6 0.03 14.7 12.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Histone_HNS PF00816.21 EIM79988.1 - 0.025 15.4 3.1 0.039 14.8 3.1 1.2 1 0 0 1 1 1 0 H-NS histone family DUF1664 PF07889.12 EIM79988.1 - 0.031 14.3 2.3 0.042 13.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FUSC PF04632.12 EIM79988.1 - 0.041 12.4 9.5 0.048 12.2 9.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AIP3 PF03915.13 EIM79988.1 - 0.041 13.0 3.1 0.047 12.8 3.1 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Noelin-1 PF12308.8 EIM79988.1 - 0.049 13.6 4.1 0.072 13.1 4.1 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein FapA PF03961.13 EIM79988.1 - 0.059 12.0 1.0 0.069 11.7 1.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A THOC7 PF05615.13 EIM79988.1 - 0.14 12.4 5.2 0.19 12.0 5.2 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 HemX PF04375.14 EIM79988.1 - 0.19 11.0 16.7 0.25 10.6 16.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase UPF0242 PF06785.11 EIM79988.1 - 0.19 11.8 9.1 0.26 11.4 9.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mod_r PF07200.13 EIM79988.1 - 0.2 11.8 8.6 0.26 11.4 8.6 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Lectin_N PF03954.14 EIM79988.1 - 0.25 11.1 9.0 0.37 10.5 9.0 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2203 PF09969.9 EIM79988.1 - 0.53 11.0 3.3 0.79 10.4 3.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FlxA PF14282.6 EIM79988.1 - 0.58 10.2 25.6 0.82 9.7 25.6 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF3573 PF12097.8 EIM79988.1 - 0.65 8.8 6.9 0.8 8.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4407 PF14362.6 EIM79988.1 - 0.7 9.2 10.1 0.9 8.8 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AI-2E_transport PF01594.16 EIM79988.1 - 0.79 8.8 3.7 1 8.5 3.7 1.1 1 0 0 1 1 1 0 AI-2E family transporter Sulfatase_C PF14707.6 EIM79988.1 - 1.1 10.1 4.2 1.6 9.5 3.9 1.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase BORCS7 PF16088.5 EIM79988.1 - 1.6 9.0 10.4 2.3 8.5 10.4 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 TFIIA PF03153.13 EIM79988.1 - 3.4 7.6 17.7 3.6 7.5 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Uso1_p115_C PF04871.13 EIM79988.1 - 4.9 7.5 8.4 7.3 7.0 8.4 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SKA2 PF16740.5 EIM79988.1 - 6.7 6.5 15.7 36 4.2 15.2 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Sorb PF02208.16 EIM79989.1 - 0.15 11.9 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Sorbin homologous domain Pkinase_fungal PF17667.1 EIM79990.1 - 2.3e-62 211.1 0.0 1.3e-60 205.4 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Uso1_p115_head PF04869.14 EIM79990.1 - 0.12 11.4 0.0 0.3 10.2 0.0 1.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region Phe_hydrox_dim PF07976.12 EIM79992.1 - 4.4e-05 23.6 0.0 5.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain TPR_10 PF13374.6 EIM79993.1 - 3.2e-60 198.5 28.6 2.8e-06 27.0 0.2 13.6 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 EIM79993.1 - 5e-23 81.2 26.1 0.0018 18.5 0.1 11.0 6 5 6 12 12 11 7 Tetratricopeptide repeat ANAPC5 PF12862.7 EIM79993.1 - 1.3e-15 57.2 19.5 0.86 9.7 0.1 11.0 4 3 6 11 11 11 5 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 EIM79993.1 - 1.4e-11 43.6 12.2 1.7 9.0 0.0 10.2 10 0 0 10 10 10 3 Tetratricopeptide repeat NACHT PF05729.12 EIM79993.1 - 4.9e-10 39.6 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF3856 PF12968.7 EIM79993.1 - 2.3e-08 34.2 3.7 0.23 11.5 0.0 5.8 3 1 2 6 6 6 2 Domain of Unknown Function (DUF3856) AAA_16 PF13191.6 EIM79993.1 - 2.1e-07 31.5 6.4 2.9e-06 27.8 0.0 4.4 2 1 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.6 EIM79993.1 - 2.5e-05 24.1 3.9 5.9 7.4 0.1 8.0 10 0 0 10 10 8 1 Tetratricopeptide repeat Desmo_N PF06771.11 EIM79993.1 - 0.00024 21.4 0.0 2.8 8.4 0.0 5.5 5 2 2 7 7 6 1 Viral Desmoplakin N-terminus AAA_22 PF13401.6 EIM79993.1 - 0.00033 20.9 0.0 0.021 15.1 0.0 3.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EIM79993.1 - 0.0061 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA PF00004.29 EIM79993.1 - 0.02 15.3 0.0 0.06 13.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) L27_1 PF09058.10 EIM79993.1 - 0.025 14.5 1.0 18 5.4 0.0 4.1 4 0 0 4 4 2 0 L27_1 DUF4003 PF13170.6 EIM79993.1 - 0.059 12.7 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) TPR_16 PF13432.6 EIM79993.1 - 0.072 13.7 17.4 0.57 10.9 0.5 6.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Utp11 PF03998.13 EIM79993.1 - 0.27 11.1 2.5 3.1 7.7 0.1 3.4 3 2 0 3 3 3 0 Utp11 protein TPR_17 PF13431.6 EIM79993.1 - 0.45 11.0 2.9 1.4e+02 3.2 0.1 4.8 6 0 0 6 6 3 0 Tetratricopeptide repeat Pkinase_fungal PF17667.1 EIM79993.1 - 1.8 7.2 6.1 33 3.1 0.2 4.5 6 0 0 6 6 6 0 Fungal protein kinase ALIX_LYPXL_bnd PF13949.6 EIM79993.1 - 1.8 7.8 7.3 9.6 5.4 0.1 4.4 3 3 1 5 5 5 0 ALIX V-shaped domain binding to HIV TPR_6 PF13174.6 EIM79993.1 - 1.9 9.3 14.6 98 3.9 0.0 9.0 12 0 0 12 12 8 0 Tetratricopeptide repeat TrkH PF02386.16 EIM79994.1 - 4.3e-99 332.3 7.0 5.5e-96 322.0 1.0 2.1 2 0 0 2 2 2 2 Cation transport protein F-box-like PF12937.7 EIM79997.1 - 2.9e-10 39.9 1.8 3.3e-10 39.7 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM79997.1 - 0.17 11.8 4.6 9.6 6.2 1.6 3.7 4 0 0 4 4 4 0 F-box domain MFS_1 PF07690.16 EIM79998.1 - 7.4e-30 104.0 44.2 7.9e-28 97.4 19.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM79998.1 - 9.1e-10 38.0 17.4 2.7e-09 36.4 17.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter SepZ PF06066.11 EIM79998.1 - 0.066 13.4 0.9 3.2 8.0 0.0 2.7 2 0 0 2 2 2 0 SepZ DUF2530 PF10745.9 EIM79998.1 - 1.8 8.9 5.4 0.36 11.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF308 PF03729.13 EIM79998.1 - 2.6 8.4 11.5 0.041 14.2 2.1 3.0 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Amj PF10997.8 EIM79999.1 - 0.026 13.8 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 Alternate to MurJ MFS_1 PF07690.16 EIM80000.1 - 2.9e-27 95.5 29.5 2.9e-27 95.5 29.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM80000.1 - 2.7e-07 29.8 19.0 4.6e-07 29.1 19.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EIM80000.1 - 0.00092 17.7 0.3 0.0016 16.9 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 EIM80003.1 - 9.6e-10 37.9 0.2 1.6e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM80003.1 - 4.3e-06 26.7 10.1 6.7e-06 26.1 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PXB PF12828.7 EIM80003.1 - 0.0081 16.1 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 PX-associated TPT PF03151.16 EIM80004.1 - 1.1e-27 97.2 14.5 1.4e-27 96.8 14.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EIM80004.1 - 1e-07 32.2 30.4 2.7e-06 27.6 11.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EIM80004.1 - 0.00041 19.6 14.7 0.00069 18.9 14.7 1.4 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EIM80004.1 - 0.032 13.5 16.4 0.08 12.2 16.4 1.7 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport APG5 PF04106.12 EIM80008.1 - 1.5e-60 204.6 0.0 1.9e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 RNase_H PF00075.24 EIM80010.1 - 2e-12 47.5 0.0 2.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 RNase H Med31 PF05669.12 EIM80011.1 - 2.9e-35 120.1 5.3 3.7e-35 119.8 5.3 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.11 EIM80011.1 - 0.06 13.2 3.0 0.94 9.4 0.1 2.3 2 0 0 2 2 2 0 Nodule-specific GRP repeat TrkH PF02386.16 EIM80012.1 - 1.8e-30 105.8 14.5 8.1e-23 80.6 0.5 4.4 3 2 0 3 3 3 2 Cation transport protein adh_short_C2 PF13561.6 EIM80013.1 - 3.9e-25 88.8 0.1 4.9e-23 81.9 0.1 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM80013.1 - 5.2e-21 75.0 0.0 7.1e-19 68.0 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM80013.1 - 4.4e-06 26.7 0.1 0.00072 19.5 0.1 2.5 2 1 0 2 2 2 1 KR domain NmrA PF05368.13 EIM80013.1 - 0.0014 18.2 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EIM80013.1 - 0.0059 16.1 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM80013.1 - 0.0074 15.7 0.0 0.041 13.3 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase UDPG_MGDP_dh_N PF03721.14 EIM80013.1 - 0.014 15.0 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3Beta_HSD PF01073.19 EIM80013.1 - 0.075 12.0 0.0 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2652 PF10851.8 EIM80013.1 - 0.22 11.6 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) Peptidase_C12 PF01088.21 EIM80015.1 - 1.2e-52 178.8 0.0 2.6e-52 177.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EIM80015.1 - 6.6e-13 48.3 0.1 1.5e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Zn_clus PF00172.18 EIM80016.1 - 2.9e-06 27.3 6.1 5.4e-06 26.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4372 PF14294.6 EIM80018.1 - 0.057 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) zf-C2H2 PF00096.26 EIM80020.1 - 4.8e-06 26.7 5.8 0.012 16.0 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM80020.1 - 0.00086 19.9 5.6 0.82 10.7 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM80020.1 - 0.0044 17.3 0.8 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM80020.1 - 0.007 16.7 1.0 4.6 7.8 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-CHY PF05495.12 EIM80020.1 - 0.19 12.2 5.5 0.34 11.4 5.5 1.3 1 0 0 1 1 1 0 CHY zinc finger Macoilin PF09726.9 EIM80020.1 - 0.33 9.4 0.8 0.43 9.1 0.8 1.1 1 0 0 1 1 1 0 Macoilin family FRG2 PF15315.6 EIM80020.1 - 2.1 8.5 9.8 3.2 7.9 9.8 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 zf-BED PF02892.15 EIM80020.1 - 2.7 8.1 5.9 15 5.7 0.9 2.4 1 1 1 2 2 2 0 BED zinc finger ALP_N PF17989.1 EIM80021.1 - 0.055 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Actin like proteins N terminal domain SnoaL PF07366.12 EIM80022.1 - 0.0014 18.4 1.8 0.032 14.0 1.8 2.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF1772 PF08592.11 EIM80024.1 - 2.1e-28 99.4 7.8 2.6e-28 99.0 7.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SPT_ssu-like PF11779.8 EIM80025.1 - 3.9 7.2 7.5 0.98 9.1 0.5 2.7 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like DUF5326 PF17260.2 EIM80025.1 - 8.2 6.6 9.4 3.5 7.8 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5326) Peptidase_C14 PF00656.22 EIM80026.1 - 1.3e-23 84.2 0.1 2e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Herpes_UL37_2 PF07413.11 EIM80026.1 - 0.12 11.5 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 Raptor_N PF14538.6 EIM80026.1 - 0.15 12.0 0.0 23 4.9 0.1 2.4 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 EIM80030.1 - 6.1e-20 72.2 0.0 1.1e-19 71.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CRIC_ras_sig PF10534.9 EIM80030.1 - 0.065 13.4 0.2 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras DUF2706 PF10913.8 EIM80031.1 - 0.02 14.7 1.0 0.74 9.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) GH131_N PF18271.1 EIM80032.1 - 1.2e-65 221.8 3.2 1.2e-65 221.8 3.2 1.8 2 0 0 2 2 2 1 Glycoside hydrolase 131 catalytic N-terminal domain Oxidored_FMN PF00724.20 EIM80039.1 - 1.2e-83 281.3 0.0 1.3e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.25 EIM80043.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Dor1 PF04124.12 EIM80044.1 - 2.3e-42 144.9 0.0 1.2e-41 142.5 0.0 2.0 1 1 0 1 1 1 1 Dor1-like family COG2 PF06148.11 EIM80044.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF863 PF05904.11 EIM80044.1 - 0.2 10.1 2.0 0.28 9.6 2.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) DUF992 PF06186.11 EIM80044.1 - 0.43 10.4 2.2 0.88 9.4 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) Ribonuc_L-PSP PF01042.21 EIM80048.1 - 0.0043 17.0 0.0 0.0057 16.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_28 PF00295.17 EIM80049.1 - 7.6e-57 192.8 5.2 1.1e-56 192.3 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DIM PF08194.12 EIM80052.1 - 1 9.6 2.7 24 5.3 2.7 2.6 1 1 0 1 1 1 0 DIM protein Retrotran_gag_2 PF14223.6 EIM80053.1 - 4.4e-13 49.1 0.2 4.9e-13 48.9 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.22 EIM80053.1 - 0.034 13.8 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SUV3_C PF12513.8 EIM80054.1 - 0.06 13.3 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal DNA_pol_phi PF04931.13 EIM80054.1 - 0.11 10.6 4.9 0.14 10.2 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4554 PF15091.6 EIM80054.1 - 0.81 8.5 4.4 1.3 7.9 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Cauli_VI PF01693.16 EIM80058.1 - 1.1e-14 54.4 0.3 3.8e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin SOG2 PF10428.9 EIM80058.1 - 0.13 11.4 4.7 0.15 11.3 4.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EIM80058.1 - 0.67 9.8 5.6 1 9.2 5.6 1.3 1 0 0 1 1 1 0 SPX domain Rab5-bind PF09311.11 EIM80061.1 - 0.0048 16.3 0.3 0.0056 16.1 0.3 1.0 1 0 0 1 1 1 1 Rabaptin-like protein ORC6 PF05460.13 EIM80062.1 - 1.5 8.1 4.2 2.2 7.5 4.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) KDZ PF18758.1 EIM80063.1 - 2.4e-57 194.1 0.0 3.6e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM80063.1 - 3.8e-24 84.9 0.7 3.5e-22 78.6 0.5 2.8 2 1 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 EIM80063.1 - 0.76 10.0 13.7 0.062 13.5 8.2 2.1 2 0 0 2 2 2 0 B-box zinc finger CEBP_ZZ PF16366.5 EIM80063.1 - 2.5 8.4 7.5 7.4 6.9 7.5 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain KDZ PF18758.1 EIM80069.1 - 8e-48 163.0 0.2 8.8e-48 162.8 0.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Transp_cyt_pur PF02133.15 EIM80070.1 - 1.8e-114 382.9 36.8 2.1e-114 382.7 36.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 EIM80071.1 - 1.3e-48 165.7 0.0 1.8e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM80071.1 - 3.1e-47 161.0 0.0 4.2e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EIM80071.1 - 6.5e-08 32.3 0.5 1.2e-07 31.5 0.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 EIM80071.1 - 0.004 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 EIM80071.1 - 0.0079 16.1 4.1 0.015 15.2 4.1 1.4 1 0 0 1 1 1 1 PHD-finger APH PF01636.23 EIM80071.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_2 PF03107.16 EIM80071.1 - 0.037 14.4 0.5 0.072 13.4 0.5 1.5 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 EIM80071.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 PHD-finger Haspin_kinase PF12330.8 EIM80071.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Prok-RING_1 PF14446.6 EIM80071.1 - 0.7 9.9 6.6 0.25 11.3 3.8 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DIOX_N PF14226.6 EIM80072.1 - 1e-28 100.4 0.0 1.6e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM80072.1 - 3.6e-16 59.5 0.0 6.4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 EIM80073.1 - 4.3e-15 55.5 0.1 9.7e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM80073.1 - 3.5e-06 27.0 9.1 6e-06 26.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_3 PF07969.11 EIM80074.1 - 4.8e-79 267.0 0.0 6.2e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EIM80074.1 - 3.8e-07 29.7 0.1 0.0003 20.2 0.0 3.2 2 1 0 2 2 2 2 Amidohydrolase family CTP_transf_like PF01467.26 EIM80075.1 - 1.2e-25 90.4 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like SapA PF02199.15 EIM80075.1 - 0.013 15.7 0.3 0.022 15.0 0.3 1.2 1 0 0 1 1 1 0 Saposin A-type domain GHL10 PF02638.15 EIM80075.1 - 0.069 12.2 0.2 0.087 11.9 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 tRNA-synt_2 PF00152.20 EIM80076.1 - 9.8e-68 228.5 0.0 1.6e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EIM80076.1 - 6.9e-23 81.1 0.3 1.2e-22 80.3 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EIM80076.1 - 3.7e-05 23.6 0.2 0.00011 22.1 0.2 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Zip PF02535.22 EIM80076.1 - 0.88 8.7 2.2 1.3 8.2 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NAM-associated PF14303.6 EIM80076.1 - 2.8 8.6 10.7 6.8 7.4 10.7 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain IMPDH PF00478.25 EIM80078.1 - 2.7e-129 431.1 2.7 6.2e-128 426.6 2.7 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EIM80078.1 - 1e-14 54.7 1.1 3.4e-08 33.8 0.0 3.2 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 EIM80078.1 - 1.5e-10 40.6 0.8 3e-10 39.7 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EIM80078.1 - 6.7e-06 25.7 11.3 8.3e-05 22.1 7.7 3.0 2 1 1 3 3 3 1 Nitronate monooxygenase His_biosynth PF00977.21 EIM80078.1 - 9e-05 22.0 1.6 0.0006 19.3 1.6 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EIM80078.1 - 0.0012 18.2 1.0 0.0026 17.1 1.0 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IGPS PF00218.21 EIM80078.1 - 0.05 12.8 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF561 PF04481.12 EIM80078.1 - 0.052 12.7 1.0 0.63 9.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) HK PF02110.15 EIM80078.1 - 0.14 11.5 3.2 0.38 10.1 0.1 2.7 2 1 0 2 2 2 0 Hydroxyethylthiazole kinase family Formyl_trans_C PF02911.18 EIM80078.1 - 0.15 12.3 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain YpsA PF06908.11 EIM80078.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family G3P_antiterm PF04309.12 EIM80078.1 - 0.21 11.0 1.0 1.3 8.4 0.2 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 EIM80078.1 - 0.31 10.1 1.1 1.1 8.3 0.1 1.9 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Glyco_hydro_3 PF00933.21 EIM80079.1 - 3.3e-84 283.0 0.1 4.1e-84 282.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain VHS PF00790.19 EIM80080.1 - 1.6e-12 47.5 0.0 2.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EIM80081.1 - 1.7e-10 41.0 0.3 2e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 GAT domain MCM_bind PF09739.9 EIM80081.1 - 0.27 9.7 2.0 0.38 9.1 2.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF3915 PF13054.6 EIM80081.1 - 1.3 9.0 10.0 4.3 7.3 10.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) COG7 PF10191.9 EIM80082.1 - 1.9e-69 234.8 2.9 2.3e-37 128.7 0.3 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) Sec10 PF07393.11 EIM80082.1 - 0.023 13.2 0.1 0.066 11.6 0.1 1.7 1 1 0 1 1 1 0 Exocyst complex component Sec10 Pyr_redox_2 PF07992.14 EIM80083.1 - 2.7e-64 217.3 12.4 5.8e-64 216.1 9.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EIM80083.1 - 2e-41 140.7 0.6 2e-41 140.7 0.6 3.0 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EIM80083.1 - 9.5e-19 67.7 11.0 2.1e-17 63.4 2.5 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM80083.1 - 6.5e-11 42.2 0.4 6.5e-11 42.2 0.4 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EIM80083.1 - 3e-10 39.7 0.9 3e-10 39.7 0.9 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EIM80083.1 - 5.9e-08 32.3 7.5 8.5e-06 25.2 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM80083.1 - 1e-07 32.1 4.3 0.00051 20.2 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIM80083.1 - 1.7e-06 27.0 12.2 9.3e-05 21.3 0.2 4.1 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EIM80083.1 - 4.7e-06 26.1 7.0 0.003 16.9 0.8 3.3 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EIM80083.1 - 5e-06 25.8 3.3 5e-06 25.8 3.3 4.1 3 1 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.6 EIM80083.1 - 1.8e-05 24.1 1.0 0.0099 15.1 0.1 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EIM80083.1 - 0.0014 17.9 0.1 0.0014 17.9 0.1 2.6 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 EIM80083.1 - 0.0017 18.0 19.3 0.24 10.9 0.5 4.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIM80083.1 - 0.0039 16.5 14.0 0.031 13.5 1.5 3.4 3 0 0 3 3 3 1 FAD binding domain DUF4479 PF14794.6 EIM80083.1 - 0.02 14.7 1.4 4.1 7.3 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) 3HCDH_N PF02737.18 EIM80083.1 - 0.11 12.4 1.0 0.32 10.9 1.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EIM80083.1 - 0.31 10.3 4.0 0.34 10.2 0.5 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 EIM80083.1 - 0.93 9.0 4.6 11 5.5 1.9 3.1 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 EIM80083.1 - 1.1 8.3 8.0 0.38 9.7 0.4 3.2 3 1 0 3 3 3 0 Lycopene cyclase protein DUF3435 PF11917.8 EIM80084.1 - 8.2e-40 137.0 0.4 1.2e-39 136.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-Di19 PF05605.12 EIM80084.1 - 0.063 13.6 11.8 5.3 7.4 0.2 4.9 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding AAA_12 PF13087.6 EIM80085.1 - 5.4e-56 189.4 0.0 8.8e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM80085.1 - 1.8e-50 172.2 0.0 2.4e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM80085.1 - 1.5e-14 54.6 0.1 5.2e-14 52.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM80085.1 - 3e-10 40.1 0.2 7.1e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 EIM80085.1 - 4.7e-06 26.3 0.0 1.8e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EIM80085.1 - 4.5e-05 23.3 0.1 1.5 8.5 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EIM80085.1 - 0.092 13.2 0.1 0.38 11.2 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GAS PF13851.6 EIM80085.1 - 0.12 11.8 2.5 0.19 11.1 2.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ResIII PF04851.15 EIM80085.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_6 PF12774.7 EIM80085.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EIM80085.1 - 0.24 10.9 0.1 1.8 8.1 0.2 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 EIM80085.1 - 0.39 10.6 1.8 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain zf-RanBP PF00641.18 EIM80086.1 - 3.1e-05 23.2 12.7 0.00099 18.4 0.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Prim_Zn_Ribbon PF08273.12 EIM80086.1 - 0.44 10.9 3.8 2.5 8.4 0.1 2.8 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DUF3403 PF11883.8 EIM80086.1 - 4.6 7.4 10.8 5.6 7.2 1.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3403) APC1_C PF18122.1 EIM80087.1 - 1.8e-37 128.9 0.5 3.9e-37 127.8 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EIM80087.1 - 0.00025 21.6 7.2 0.00057 20.4 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EIM80087.1 - 0.0028 18.0 5.9 0.55 10.8 0.0 4.5 4 0 0 4 4 4 2 Proteasome/cyclosome repeat DAHP_synth_1 PF00793.20 EIM80088.1 - 4.4e-100 334.1 0.0 5.4e-100 333.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2313 PF10076.9 EIM80088.1 - 0.011 15.7 0.1 0.032 14.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) PIH1 PF08190.12 EIM80089.1 - 9.1e-23 80.5 0.0 1.4e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain GMC_oxred_N PF00732.19 EIM80090.1 - 6.8e-70 235.8 0.0 1e-69 235.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM80090.1 - 2.7e-33 115.5 0.0 4.8e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM80090.1 - 1.3e-06 27.8 0.1 0.012 14.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EIM80090.1 - 3.7e-06 26.8 1.3 0.0012 18.5 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM80090.1 - 6.1e-06 25.5 0.9 1.7e-05 24.1 0.6 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EIM80090.1 - 0.0042 16.3 0.1 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EIM80090.1 - 0.0074 16.5 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM80090.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding BCS1_N PF08740.11 EIM80091.1 - 8.9e-43 146.4 2.5 8.9e-43 146.4 2.5 2.3 3 0 0 3 3 2 1 BCS1 N terminal AAA PF00004.29 EIM80091.1 - 6.7e-15 55.7 0.0 1.1e-06 29.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EIM80091.1 - 0.00046 19.4 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EIM80091.1 - 0.0051 17.2 0.1 0.0051 17.2 0.1 2.8 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 EIM80091.1 - 0.0078 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EIM80091.1 - 0.098 12.4 0.8 0.25 11.1 0.0 2.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 EIM80091.1 - 0.16 12.1 0.2 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase PA26 PF04636.13 EIM80091.1 - 0.18 10.7 3.1 0.33 9.8 3.1 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ABC_tran PF00005.27 EIM80091.1 - 0.57 10.7 2.6 0.39 11.2 0.2 2.0 2 1 0 2 2 2 0 ABC transporter GAGA_bind PF06217.12 EIM80091.1 - 0.91 9.8 10.6 0.17 12.1 5.5 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4887 PF16228.5 EIM80091.1 - 1.7 8.8 17.3 0.024 14.8 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) CPSF100_C PF13299.6 EIM80091.1 - 2.1 8.5 18.4 16 5.6 0.0 2.9 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA_23 PF13476.6 EIM80091.1 - 3.1 8.3 13.4 11 6.5 0.8 2.9 2 1 0 2 2 2 0 AAA domain FemAB PF02388.16 EIM80091.1 - 6 5.6 12.1 0.24 10.2 5.9 1.6 2 0 0 2 2 2 0 FemAB family Dynamin_N PF00350.23 EIM80091.1 - 7.8 6.5 6.3 11 6.1 0.3 2.5 2 1 0 2 2 2 0 Dynamin family Connexin PF00029.19 EIM80091.1 - 8.5 6.1 7.6 19 4.9 3.2 2.2 2 0 0 2 2 2 0 Connexin GMC_oxred_N PF00732.19 EIM80093.1 - 4.7e-66 223.2 0.0 6.1e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM80093.1 - 4.7e-35 121.2 0.1 7.8e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM80093.1 - 6e-05 22.3 0.5 0.00013 21.2 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EIM80093.1 - 0.0072 15.9 3.3 0.057 13.0 3.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM80093.1 - 0.1 12.9 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM80093.1 - 0.19 10.8 1.5 3.2 6.7 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain COX14 PF14880.6 EIM80095.1 - 6.2e-07 29.2 1.0 6.2e-07 29.2 1.0 1.9 2 1 0 2 2 2 1 Cytochrome oxidase c assembly DUF5333 PF17267.2 EIM80095.1 - 0.049 13.8 0.1 0.065 13.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5333) NLE PF08154.12 EIM80096.1 - 1.7e-14 54.1 0.0 3.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 EIM80096.1 - 6.7e-10 39.4 13.9 0.19 12.6 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF1125 PF06563.11 EIM80096.1 - 0.18 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) TauD PF02668.16 EIM80098.1 - 2.2e-52 178.5 1.2 3.2e-52 178.0 0.5 1.6 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EIM80098.1 - 2.3e-10 40.9 0.1 1e-09 38.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF971) DUF2442 PF10387.9 EIM80098.1 - 0.038 14.3 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) CsiD PF08943.10 EIM80098.1 - 0.054 12.6 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 CsiD SRAP PF02586.14 EIM80100.1 - 1.8e-52 178.0 0.3 4.9e-34 117.8 0.1 2.0 2 0 0 2 2 2 2 SOS response associated peptidase (SRAP) CUE PF02845.16 EIM80101.1 - 8.4e-08 31.8 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain DSPc PF00782.20 EIM80102.1 - 2.7e-26 92.0 0.0 4.5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 EIM80102.1 - 0.00095 19.7 0.0 0.0096 16.4 0.0 2.6 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 EIM80102.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EIM80102.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EIM80102.1 - 0.2 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate SRAP PF02586.14 EIM80103.1 - 4e-65 219.4 0.1 6.9e-65 218.7 0.1 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Glyco_hydro_61 PF03443.14 EIM80104.1 - 5.4e-63 212.6 0.1 9.3e-63 211.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EIM80104.1 - 1.6e-09 37.6 9.4 1.6e-09 37.6 9.4 1.9 1 1 0 1 1 1 1 Fungal cellulose binding domain SOG2 PF10428.9 EIM80104.1 - 9.7 5.3 7.7 14 4.8 7.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein eIF-5a PF01287.20 EIM80105.1 - 2.8e-29 101.0 0.7 4.1e-29 100.5 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EIM80105.1 - 0.0081 16.2 0.3 0.015 15.3 0.1 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain HAMP PF00672.25 EIM80106.1 - 5.5e-60 199.6 30.2 1.4e-07 31.8 0.1 12.3 10 2 1 11 11 11 10 HAMP domain HATPase_c PF02518.26 EIM80106.1 - 3.2e-29 101.7 0.0 1e-28 100.1 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM80106.1 - 8.7e-23 80.6 0.4 3.3e-22 78.7 0.4 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EIM80106.1 - 4.1e-17 62.0 3.4 1.2e-16 60.5 1.0 3.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 EIM80106.1 - 8.4e-06 25.1 1.6 0.022 13.9 0.1 4.6 2 2 3 5 5 5 2 Autophagy protein Apg17 Syntaxin_2 PF14523.6 EIM80106.1 - 0.00026 21.3 5.7 43 4.6 0.0 6.9 3 3 1 5 5 5 0 Syntaxin-like protein DUF3829 PF12889.7 EIM80106.1 - 0.00041 19.9 1.6 8.6 5.8 0.0 5.9 5 3 3 9 9 9 1 Protein of unknown function (DUF3829) PhoR PF11808.8 EIM80106.1 - 0.00073 19.9 0.0 69 4.0 0.0 6.1 8 0 0 8 8 6 0 Phosphate regulon sensor protein PhoR Baculo_PEP_C PF04513.12 EIM80106.1 - 0.0037 17.3 49.0 0.19 11.8 1.2 9.5 1 1 7 9 9 9 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 EIM80106.1 - 0.0078 15.8 2.7 29 4.2 0.1 5.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4795) GatB_Yqey PF02637.18 EIM80106.1 - 0.13 12.1 6.4 4.5 7.2 0.0 5.0 5 0 0 5 5 5 0 GatB domain FYVE PF01363.21 EIM80106.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger Fez1 PF06818.15 EIM80106.1 - 0.5 10.8 7.6 1.3 9.4 1.2 4.4 3 2 0 3 3 3 0 Fez1 DUF948 PF06103.11 EIM80106.1 - 0.7 10.2 70.4 0.52 10.6 1.8 14.0 7 5 2 10 10 9 0 Bacterial protein of unknown function (DUF948) Focal_AT PF03623.13 EIM80106.1 - 1.2 9.2 10.3 2.9 7.9 0.1 5.5 3 2 2 5 5 5 0 Focal adhesion targeting region FlaC_arch PF05377.11 EIM80106.1 - 3.3 8.2 25.9 22 5.5 0.0 8.8 10 0 0 10 10 9 0 Flagella accessory protein C (FlaC) Peptidase_M75 PF09375.10 EIM80106.1 - 5 6.5 15.5 0.26 10.7 0.7 5.0 4 3 3 7 7 7 0 Imelysin EMP70 PF02990.16 EIM80108.1 - 0.093 11.4 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 Ldi PF18566.1 EIM80109.1 - 5.7e-136 453.2 0.0 7e-136 452.9 0.0 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase Adipogenin PF15202.6 EIM80109.1 - 0.017 15.1 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Adipogenin PAP_assoc PF03828.19 EIM80110.1 - 1e-14 54.4 0.2 3e-14 53.0 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EIM80110.1 - 6e-05 23.3 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EIM80110.1 - 0.029 14.5 0.1 0.081 13.0 0.0 1.7 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Tri3 PF07428.11 EIM80111.1 - 0.00025 20.1 0.1 0.0011 18.0 0.1 1.8 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 LSM PF01423.22 EIM80113.1 - 1.3e-20 72.9 0.0 1.5e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EIM80113.1 - 0.048 13.8 0.2 0.12 12.5 0.2 1.6 1 1 1 2 2 2 0 RimP C-terminal SH3 domain HEAT PF02985.22 EIM80114.1 - 1.1e-18 65.6 12.0 6.8e-05 22.8 0.0 9.4 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 EIM80114.1 - 6.7e-18 64.8 7.5 5.7e-11 42.7 0.0 6.7 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 EIM80114.1 - 3.6e-10 40.1 1.8 0.0037 17.6 0.1 5.7 2 2 1 4 4 4 3 HEAT repeats IBN_N PF03810.19 EIM80114.1 - 5.7e-09 35.8 0.2 2.2e-07 30.7 0.2 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 EIM80114.1 - 2.1e-08 33.9 1.4 0.0027 17.7 0.0 4.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 EIM80114.1 - 7.9e-05 22.6 0.3 0.11 12.5 0.0 4.0 2 2 0 2 2 2 2 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EIM80114.1 - 0.00055 19.2 1.9 0.16 11.0 0.0 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Uso1_p115_head PF04869.14 EIM80114.1 - 0.031 13.4 0.4 0.88 8.6 0.1 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region TIP120 PF08623.10 EIM80114.1 - 0.041 13.7 0.1 0.97 9.2 0.0 3.0 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.7 EIM80114.1 - 0.053 13.6 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PPR_2 PF13041.6 EIM80115.1 - 6.2e-08 32.7 0.2 7.8e-05 22.8 0.0 4.5 4 1 1 5 5 5 1 PPR repeat family PPR PF01535.20 EIM80115.1 - 0.016 15.4 1.1 4.5 7.7 0.0 4.6 6 0 0 6 6 6 0 PPR repeat PPR_3 PF13812.6 EIM80115.1 - 0.042 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 EIM80115.1 - 0.044 13.5 5.1 4.3 7.1 0.0 4.2 5 0 0 5 5 5 0 PPR repeat F-box-like PF12937.7 EIM80116.1 - 2.3e-05 24.2 0.6 7.2e-05 22.6 0.6 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM80116.1 - 2.4 8.7 10.1 2.1 8.9 0.3 4.5 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Beta-lactamase PF00144.24 EIM80117.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase DUF4788 PF16032.5 EIM80119.1 - 0.17 10.8 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) DUF5543 PF17697.1 EIM80119.1 - 0.44 10.8 2.3 0.57 10.5 1.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5543) Lon_C PF05362.13 EIM80122.1 - 9.4e-64 214.7 2.0 4.5e-62 209.2 2.0 2.4 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EIM80122.1 - 8.4e-22 78.0 0.0 2e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM80122.1 - 3.1e-10 40.2 0.0 6.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 EIM80122.1 - 1.1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 EIM80122.1 - 4.2e-06 26.6 0.0 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EIM80122.1 - 0.00014 22.3 0.5 0.00014 22.3 0.5 3.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EIM80122.1 - 0.00055 20.1 0.1 0.0025 18.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EIM80122.1 - 0.00079 19.2 0.0 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EIM80122.1 - 0.0046 17.1 0.0 0.019 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EIM80122.1 - 0.0097 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EIM80122.1 - 0.01 15.6 0.0 0.035 13.8 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 EIM80122.1 - 0.024 14.9 3.3 0.34 11.2 0.3 3.5 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EIM80122.1 - 0.029 14.9 0.3 0.096 13.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EIM80122.1 - 0.12 12.4 0.0 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EIM80122.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EIM80122.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EIM80122.1 - 3.4 7.9 6.1 4.4 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain Pan3_PK PF18101.1 EIM80126.1 - 1.5e-64 216.1 0.1 2.4e-64 215.5 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EIM80126.1 - 0.00023 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM80126.1 - 0.0027 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SpoIIID PF12116.8 EIM80126.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Stage III sporulation protein D TFA2_Winged_2 PF18121.1 EIM80127.1 - 3.1e-19 68.4 0.1 6.4e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EIM80127.1 - 2.5e-13 50.1 0.1 9.5e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain zf-MYND PF01753.18 EIM80129.1 - 2.2e-10 40.4 18.5 5.1e-10 39.3 18.5 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM80129.1 - 0.25 11.7 17.6 0.14 12.5 15.0 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DNA_pol_B_palm PF14792.6 EIM80131.1 - 1.4e-25 89.7 0.1 2.7e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EIM80131.1 - 3.9e-19 68.6 0.0 9.3e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EIM80131.1 - 7e-19 67.4 1.3 1.1e-17 63.6 0.3 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EIM80131.1 - 9.3e-09 35.5 0.0 2.8e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 EIM80131.1 - 0.031 14.9 0.0 17 6.1 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain BRCT PF00533.26 EIM80131.1 - 0.037 14.4 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 EIM80131.1 - 0.043 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain p450 PF00067.22 EIM80132.1 - 9.3e-67 225.7 0.0 1.1e-66 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIM PF00412.22 EIM80133.1 - 2.1e-25 88.7 20.7 3e-13 49.8 5.7 2.2 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.10 EIM80133.1 - 0.27 11.4 22.0 2 8.6 0.1 4.3 4 0 0 4 4 4 0 Zinc ribbon domain DUF2616 PF11077.8 EIM80133.1 - 0.27 10.9 3.8 1.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) DZR PF12773.7 EIM80133.1 - 0.49 10.4 22.5 15 5.7 2.6 4.3 2 2 1 3 3 3 0 Double zinc ribbon zf_UBZ PF18439.1 EIM80133.1 - 1.9 8.2 22.3 4.8 6.9 0.5 5.3 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger YacG PF03884.14 EIM80133.1 - 4.5 7.1 16.2 3.8 7.3 0.3 4.0 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG zinc_ribbon_13 PF09855.9 EIM80133.1 - 6.7 7.0 9.7 1.2 9.4 0.2 3.8 4 0 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Bromo_TP PF07524.13 EIM80134.1 - 3.4e-08 33.4 0.1 5.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 EIM80134.1 - 0.046 14.1 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIM80134.1 - 0.14 12.3 0.1 0.38 10.9 0.1 1.7 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold MARVEL PF01284.23 EIM80135.1 - 0.036 14.1 5.4 0.073 13.1 5.4 1.6 1 1 0 1 1 1 0 Membrane-associating domain DUF3285 PF11688.8 EIM80135.1 - 2.4 8.2 5.4 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Ish1 PF10281.9 EIM80136.1 - 2.3e-51 171.8 31.1 6e-11 42.5 2.4 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EIM80136.1 - 7.3e-07 28.8 0.2 2.4 8.0 0.0 5.3 5 0 0 5 5 5 3 HeH/LEM domain Slx4 PF09494.10 EIM80136.1 - 0.00063 19.6 1.9 15 5.7 0.0 5.1 4 2 0 4 4 4 2 Slx4 endonuclease LEM PF03020.15 EIM80136.1 - 0.088 12.4 0.0 32 4.2 0.0 3.6 3 0 0 3 3 3 0 LEM domain TryThrA_C PF12319.8 EIM80136.1 - 0.39 10.2 30.1 0.12 11.9 9.5 3.7 3 1 0 3 3 3 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Integrase_H2C2 PF17921.1 EIM80137.1 - 4.3e-07 30.0 3.4 4.3e-07 30.0 3.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Gp_dh_C PF02800.20 EIM80138.1 - 6.2e-69 230.6 0.0 8.8e-69 230.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EIM80138.1 - 1e-38 131.7 0.3 3.1e-38 130.2 0.2 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EIM80138.1 - 0.018 15.1 0.8 0.037 14.2 0.3 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EIM80138.1 - 0.049 13.6 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pkinase PF00069.25 EIM80140.1 - 3.3e-72 243.0 0.0 4.6e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM80140.1 - 5.2e-39 134.1 0.0 8.5e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM80140.1 - 2.2e-06 27.2 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIM80140.1 - 0.0055 15.7 0.2 0.009 15.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain KA1 PF02149.19 EIM80140.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 APH PF01636.23 EIM80140.1 - 0.049 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EIM80140.1 - 0.057 13.0 0.2 0.057 13.0 0.2 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 EIM80142.1 - 3e-11 43.2 0.0 3.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain P16-Arc PF04699.14 EIM80143.1 - 2.9e-52 177.1 0.0 3.2e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 EIM80143.1 - 0.00049 20.4 0.0 0.00076 19.8 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Lyase_1 PF00206.20 EIM80146.1 - 6.6e-19 68.4 0.0 1.4e-18 67.4 0.0 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 EIM80146.1 - 1.3e-14 54.5 0.1 3.1e-12 46.9 0.0 3.4 2 1 0 2 2 2 1 Adenylosuccinate lyase C-terminus WD40 PF00400.32 EIM80148.1 - 8e-10 39.2 11.4 2e-05 25.3 0.2 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat SUR7 PF06687.12 EIM80149.1 - 4e-08 33.2 23.3 8.5e-07 28.8 22.0 2.8 1 1 1 2 2 2 1 SUR7/PalI family DUF2768 PF10966.8 EIM80149.1 - 0.61 10.6 0.1 0.61 10.6 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2768) G3P_acyltransf PF02660.15 EIM80149.1 - 3.7 7.6 11.3 0.24 11.5 4.4 2.2 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase Mito_carr PF00153.27 EIM80150.1 - 6.7e-65 215.1 4.3 3.4e-21 75.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIM80150.1 - 1.4 8.0 6.2 2.3 7.3 0.3 3.3 2 2 0 3 3 3 0 Gammaproteobacterial serine protease Tim17 PF02466.19 EIM80150.1 - 7.8 6.9 7.1 4.3e+02 1.3 7.1 3.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family HEM4 PF02602.15 EIM80151.1 - 1.1e-27 96.9 0.0 4.1e-26 91.8 0.0 2.8 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD HSP70 PF00012.20 EIM80152.1 - 5.7e-80 269.2 1.2 5.7e-80 269.2 1.2 2.3 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EIM80152.1 - 1.1e-05 24.5 1.6 2.5e-05 23.3 1.6 1.6 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 EIM80152.1 - 0.027 14.2 1.0 0.059 13.1 1.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HIP1_clath_bdg PF16515.5 EIM80152.1 - 0.031 14.9 1.1 0.13 12.9 0.1 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BcrAD_BadFG PF01869.20 EIM80152.1 - 0.053 13.0 1.8 0.084 12.4 0.4 2.1 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Membr_traf_MHD PF10540.9 EIM80153.1 - 2.4e-25 89.4 0.1 1.2e-11 45.0 0.0 2.7 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EIM80153.1 - 1.1e-10 41.7 0.0 2.8e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain MPP6 PF10175.9 EIM80156.1 - 0.00095 19.7 2.7 0.0013 19.2 0.0 2.5 1 1 1 2 2 2 1 M-phase phosphoprotein 6 MAP65_ASE1 PF03999.12 EIM80156.1 - 2.2 6.9 8.9 2.9 6.5 8.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Big_11 PF18200.1 EIM80157.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain Glyco_hydro_79C PF16862.5 EIM80158.1 - 2.4e-18 66.9 2.7 2.8e-18 66.7 0.1 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Cauli_VI PF01693.16 EIM80160.1 - 1.2e-07 31.9 0.3 4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Caulimovirus viroplasmin F-box-like PF12937.7 EIM80161.1 - 2.2e-06 27.5 0.3 7.1e-05 22.6 0.3 2.9 1 1 0 1 1 1 1 F-box-like zf-C3HC4_2 PF13923.6 EIM80164.1 - 8.4e-10 38.3 9.6 1.5e-09 37.6 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM80164.1 - 3.8e-08 33.1 9.1 6.2e-08 32.4 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM80164.1 - 5.2e-08 32.8 9.2 1.1e-07 31.7 9.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM80164.1 - 9.2e-07 28.6 5.1 1.5e-06 28.0 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM80164.1 - 1.6e-06 28.1 9.9 2.7e-06 27.4 9.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EIM80164.1 - 2.2e-06 27.4 2.3 5.2e-06 26.2 2.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EIM80164.1 - 1.1e-05 25.3 8.6 4.4e-05 23.4 8.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 EIM80164.1 - 0.00022 21.0 4.1 0.00041 20.1 4.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 EIM80164.1 - 0.00022 21.5 9.4 0.00046 20.5 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 EIM80164.1 - 0.0027 17.8 2.6 0.0057 16.8 2.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EIM80164.1 - 0.0065 16.3 10.2 0.23 11.3 11.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EIM80164.1 - 0.048 13.5 5.3 0.22 11.3 2.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_p74_N PF08404.10 EIM80164.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal zf-ANAPC11 PF12861.7 EIM80164.1 - 0.18 11.9 3.0 0.36 10.9 3.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_5 PF17121.5 EIM80164.1 - 0.63 10.0 8.5 3.5 7.6 8.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM80164.1 - 0.63 10.4 11.2 3.6 7.9 11.3 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain DUF1272 PF06906.11 EIM80164.1 - 1.6 8.9 7.5 2.9 8.1 6.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 EIM80164.1 - 1.6 8.8 5.6 4.5 7.4 5.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EIM80164.1 - 3 8.0 7.2 16 5.7 4.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain F-box_4 PF15966.5 EIM80167.1 - 0.15 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 F-box Helitron_like_N PF14214.6 EIM80173.1 - 1.6e-16 61.1 0.0 1.8e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus p450 PF00067.22 EIM80175.1 - 1.3e-54 185.7 0.0 1.8e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trehalose_PPase PF02358.16 EIM80176.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase Pkinase PF00069.25 EIM80177.1 - 0.0018 17.7 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EIM80177.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain ABC2_membrane PF01061.24 EIM80178.1 - 2.2e-72 242.9 50.7 1.2e-40 139.2 17.8 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EIM80178.1 - 4.3e-35 121.2 0.0 1.1e-16 61.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EIM80178.1 - 8.2e-32 109.0 15.1 7.1e-28 96.3 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EIM80178.1 - 9.3e-15 55.0 0.0 2.1e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EIM80178.1 - 1.8e-07 31.7 0.0 0.00053 20.4 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM80178.1 - 3.2e-06 27.1 0.1 6e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EIM80178.1 - 2.7e-05 23.8 0.1 0.0058 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM80178.1 - 4.2e-05 23.8 0.1 0.093 13.0 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EIM80178.1 - 0.0012 18.6 0.5 0.22 11.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EIM80178.1 - 0.0016 19.0 0.0 0.45 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EIM80178.1 - 0.0034 17.3 0.0 0.42 10.5 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EIM80178.1 - 0.0041 17.4 1.3 1.2 9.4 0.2 2.8 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 EIM80178.1 - 0.0049 16.9 0.1 0.45 10.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 EIM80178.1 - 0.0056 16.3 0.6 0.64 9.6 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EIM80178.1 - 0.0077 16.4 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIM80178.1 - 0.026 14.3 0.1 8 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Septin PF00735.18 EIM80178.1 - 0.042 13.1 0.0 2.9 7.1 0.1 2.2 2 0 0 2 2 2 0 Septin SRP54 PF00448.22 EIM80178.1 - 0.062 12.9 0.0 24 4.5 0.5 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Roc PF08477.13 EIM80178.1 - 0.07 13.4 0.0 4.7 7.5 0.1 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Glug PF07581.12 EIM80178.1 - 0.094 13.2 0.5 0.32 11.5 0.5 2.0 1 0 0 1 1 1 0 The GLUG motif AAA_30 PF13604.6 EIM80178.1 - 0.11 12.2 0.3 1.8 8.3 0.4 2.2 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EIM80178.1 - 0.12 11.8 0.0 2.5 7.5 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EIM80178.1 - 0.18 12.1 0.0 39 4.6 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EIM80178.1 - 0.18 12.3 0.1 0.35 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EIM80178.1 - 0.19 11.8 0.2 0.76 9.8 0.2 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EIM80178.1 - 0.19 11.6 0.0 15 5.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain DUF1804 PF08822.11 EIM80179.1 - 0.13 12.2 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Got1 PF04178.12 EIM80180.1 - 1e-33 116.1 10.1 1.4e-33 115.6 10.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AgrB PF04647.15 EIM80180.1 - 0.01 15.1 3.9 0.014 14.7 3.9 1.2 1 0 0 1 1 1 0 Accessory gene regulator B DUF2070 PF09843.9 EIM80180.1 - 0.27 9.5 3.8 0.33 9.2 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Nup192 PF11894.8 EIM80181.1 - 2.8e-233 777.3 0.0 3.2e-233 777.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 NTP_transf_9 PF04248.12 EIM80182.1 - 4.9e-36 122.5 0.0 1.4e-28 98.6 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF427) F-box-like PF12937.7 EIM80184.1 - 8.5e-09 35.2 1.1 8.5e-09 35.2 1.1 2.6 3 0 0 3 3 3 1 F-box-like Dynein_heavy PF03028.15 EIM80184.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain MFS_1 PF07690.16 EIM80185.1 - 2.5e-15 56.3 72.0 3.2e-13 49.4 33.4 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_115 PF15979.5 EIM80186.1 - 1.9e-136 455.0 0.2 2.7e-136 454.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EIM80186.1 - 1.3e-51 174.9 0.0 2.7e-51 173.8 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain ssDBP_DBD PF18361.1 EIM80186.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain PEMT PF04191.13 EIM80188.1 - 4.7e-53 178.1 8.7 7.3e-30 103.5 1.0 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 EIM80188.1 - 0.0028 17.4 0.1 0.0057 16.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 PP-binding PF00550.25 EIM80188.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphopantetheine attachment site SKICH PF17751.1 EIM80188.1 - 0.09 13.3 0.0 0.25 11.9 0.0 1.8 1 1 0 1 1 1 0 SKICH domain F-box PF00646.33 EIM80189.1 - 0.2 11.6 0.2 23 5.0 0.0 2.5 2 0 0 2 2 2 0 F-box domain Sporozoite_P67 PF05642.11 EIM80189.1 - 0.36 8.9 4.8 0.62 8.1 4.8 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen EF1_GNE PF00736.19 EIM80191.1 - 3.8e-33 113.5 1.8 3.8e-33 113.5 1.8 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EIM80191.1 - 5.7e-14 52.3 2.5 5.7e-14 52.3 2.5 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 EIM80191.1 - 0.016 15.4 0.1 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM80191.1 - 0.016 15.4 0.3 0.08 13.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM80191.1 - 0.018 15.1 0.0 0.048 13.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 EIM80191.1 - 0.28 11.7 2.6 0.48 10.9 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) eIF2A PF08662.11 EIM80192.1 - 1.3e-05 25.1 0.1 0.0051 16.7 0.1 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EIM80192.1 - 0.0002 21.6 4.7 0.2 12.0 0.5 4.8 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM80192.1 - 0.00097 19.9 19.8 0.041 14.8 0.1 6.5 7 2 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EIM80192.1 - 0.077 11.9 0.0 4.2 6.2 0.0 2.8 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EIM80192.1 - 0.17 12.0 0.2 1.8 8.7 0.2 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 EIM80193.1 - 4.4e-08 33.3 0.5 0.2 12.0 0.0 4.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM80193.1 - 8e-08 32.8 3.6 1.7 9.7 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Frtz PF11768.8 EIM80193.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Glyco_hydro_115 PF15979.5 EIM80194.1 - 7.6e-137 456.3 0.2 1.3e-136 455.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EIM80194.1 - 8.5e-56 188.5 0.0 1.7e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain ssDBP_DBD PF18361.1 EIM80194.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain Lectin_leg-like PF03388.13 EIM80194.1 - 0.077 12.3 0.1 0.95 8.7 0.0 2.2 2 0 0 2 2 2 0 Legume-like lectin family LRR_4 PF12799.7 EIM80195.1 - 0.33 11.4 7.8 7.5 7.1 0.2 5.7 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) Isochorismatase PF00857.20 EIM80196.1 - 1.6e-33 116.3 0.0 2.8e-33 115.5 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Peptidase_C2 PF00648.21 EIM80197.1 - 7.5e-58 195.9 0.3 3.9e-40 137.7 0.1 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease DHHC PF01529.20 EIM80198.1 - 2.9e-37 127.8 18.8 5.9e-37 126.8 6.5 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Choline_transpo PF04515.12 EIM80198.1 - 0.018 14.3 0.4 0.018 14.3 0.4 2.1 2 0 0 2 2 2 0 Plasma-membrane choline transporter Sensor PF13796.6 EIM80198.1 - 3.6 7.6 7.5 1.9 8.5 0.6 2.6 2 1 0 2 2 2 0 Putative sensor Aminotran_3 PF00202.21 EIM80199.1 - 2.4e-118 395.3 0.0 2.8e-118 395.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EIM80199.1 - 0.027 13.8 0.0 0.097 11.9 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase OAM_dimer PF16554.5 EIM80199.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase F-box-like PF12937.7 EIM80200.1 - 1.1e-09 38.1 2.1 1.9e-09 37.3 1.0 2.1 2 0 0 2 2 2 1 F-box-like Dynein_heavy PF03028.15 EIM80200.1 - 0.073 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain F-box-like PF12937.7 EIM80201.1 - 5.7e-07 29.3 0.1 5.7e-07 29.3 0.1 2.3 3 0 0 3 3 3 1 F-box-like DNA_pol_phi PF04931.13 EIM80201.1 - 0.011 13.9 22.9 0.017 13.3 22.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 EIM80201.1 - 0.021 14.4 15.6 0.034 13.7 15.6 1.2 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.11 EIM80201.1 - 8 4.4 12.2 12 3.8 12.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRR_8 PF13855.6 EIM80202.1 - 0.00095 18.9 0.7 0.18 11.6 0.1 3.8 4 0 0 4 4 4 1 Leucine rich repeat TPR_14 PF13428.6 EIM80202.1 - 0.31 12.0 1.8 2 9.5 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YfhO PF09586.10 EIM80203.1 - 0.49 8.6 1.1 0.64 8.2 1.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 2OG-FeII_Oxy_2 PF13532.6 EIM80204.1 - 2.2e-13 50.8 0.0 8.1e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUDIX PF00293.28 EIM80205.1 - 7.1e-11 42.3 0.0 1.1e-10 41.6 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain dCMP_cyt_deam_1 PF00383.23 EIM80208.1 - 2.1e-11 43.6 0.0 1.3e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIM80208.1 - 0.00015 21.5 0.0 0.0082 15.9 0.0 2.1 2 0 0 2 2 2 2 MafB19-like deaminase Acetyltransf_10 PF13673.7 EIM80209.1 - 9.5e-08 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80209.1 - 1e-07 32.2 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM80209.1 - 1.8e-07 31.5 0.0 3.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM80209.1 - 7.2e-05 22.7 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EIM80209.1 - 0.0086 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EIM80209.1 - 0.054 13.1 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_4 PF13420.7 EIM80209.1 - 0.083 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 60KD_IMP PF02096.20 EIM80211.1 - 4.5e-17 62.4 4.4 7.9e-17 61.7 4.4 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein DUF202 PF02656.15 EIM80212.1 - 0.00013 22.3 3.6 0.00034 21.0 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Hist_rich_Ca-bd PF10529.9 EIM80212.1 - 0.69 10.2 4.2 1.3 9.4 4.2 1.4 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region DUF3328 PF11807.8 EIM80217.1 - 7.1e-51 173.1 0.0 8.5e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HALZ PF02183.18 EIM80217.1 - 0.89 9.8 2.5 0.71 10.1 0.6 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper F-box-like PF12937.7 EIM80218.1 - 1e-09 38.1 1.2 2.4e-09 36.9 1.2 1.7 1 0 0 1 1 1 1 F-box-like HLH PF00010.26 EIM80219.1 - 2.9e-14 52.8 0.2 8.3e-14 51.3 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4363 PF14276.6 EIM80219.1 - 0.045 13.9 0.7 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) G-alpha PF00503.20 EIM80220.1 - 4e-114 381.5 0.0 4.9e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM80220.1 - 1.4e-11 44.1 0.1 1.5e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EIM80220.1 - 0.0017 18.6 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EIM80220.1 - 0.011 15.2 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 EIM80220.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EIM80220.1 - 0.05 13.3 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 EIM80220.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EIM80220.1 - 0.14 11.4 0.1 0.14 11.4 0.1 2.1 2 1 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.27 EIM80220.1 - 0.17 11.4 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain GST_N_3 PF13417.6 EIM80221.1 - 1.8e-09 37.9 0.0 3.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM80221.1 - 4.6e-06 26.8 0.0 8.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM80221.1 - 0.00097 19.4 0.1 0.0034 17.7 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Na_H_Exchanger PF00999.21 EIM80222.1 - 1.2e-68 231.6 34.6 1.6e-68 231.3 34.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 EIM80222.1 - 0.053 13.9 1.9 4.3 7.7 0.0 3.1 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.7 EIM80223.1 - 1.6e-05 24.7 0.2 3.4e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like HNH_2 PF13391.6 EIM80224.1 - 0.11 12.7 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease SNF2_N PF00176.23 EIM80225.1 - 0.045 12.5 0.2 0.072 11.8 0.2 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain AMP-binding PF00501.28 EIM80226.1 - 1.1e-96 324.0 0.0 1.5e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM80226.1 - 0.0057 17.6 0.1 0.033 15.1 0.0 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain UBN_AB PF14075.6 EIM80227.1 - 6.6e-39 133.8 0.0 6.6e-39 133.8 0.0 1.8 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 EIM80227.1 - 3.7e-13 49.2 0.1 8.9e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Nop14 PF04147.12 EIM80227.1 - 0.48 8.6 11.2 0.76 7.9 11.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EIM80227.1 - 3.8 5.7 7.0 5.9 5.1 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Velvet PF11754.8 EIM80229.1 - 1.2e-17 64.7 0.0 1.2e-17 64.7 0.0 4.1 2 1 0 2 2 2 1 Velvet factor Velvet PF11754.8 EIM80230.1 - 6.6e-25 88.5 8.9 9e-13 48.7 2.2 2.9 1 1 1 2 2 2 2 Velvet factor SelP_N PF04592.14 EIM80230.1 - 0.25 10.7 1.9 0.3 10.4 1.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SET PF00856.28 EIM80231.1 - 6.7e-15 55.9 0.0 1.1e-14 55.2 0.0 1.4 1 0 0 1 1 1 1 SET domain HTH_21 PF13276.6 EIM80231.1 - 0.0036 17.4 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain SAF PF08666.12 EIM80231.1 - 0.094 13.4 0.1 7.8 7.2 0.0 2.4 2 0 0 2 2 2 0 SAF domain WD40 PF00400.32 EIM80232.1 - 3.5e-22 78.3 5.5 4.8e-10 39.9 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM80232.1 - 2.4e-09 37.4 0.0 0.0038 17.5 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM80232.1 - 6.8e-05 21.7 0.1 0.17 10.5 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 EIM80232.1 - 0.00054 19.8 0.1 8.2 6.5 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EIM80232.1 - 0.0088 15.4 0.0 2.5 7.3 0.0 2.6 1 1 2 3 3 3 2 WD40-like domain Nucleoporin_N PF08801.11 EIM80232.1 - 0.01 14.6 0.1 0.39 9.4 0.1 2.0 1 1 1 2 2 2 0 Nup133 N terminal like Hira PF07569.11 EIM80232.1 - 0.014 15.2 0.1 2.2 8.0 0.0 2.6 1 1 1 2 2 2 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 EIM80232.1 - 0.04 12.9 0.0 14 4.5 0.0 2.8 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S9_N PF02897.15 EIM80232.1 - 0.051 12.4 0.0 1.6 7.5 0.1 2.5 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Nbas_N PF15492.6 EIM80232.1 - 0.059 12.7 0.2 1.5 8.1 0.1 2.3 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AAA PF00004.29 EIM80234.1 - 0.068 13.6 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_61 PF03443.14 EIM80235.1 - 3.6e-43 147.9 0.0 7.8e-43 146.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Lipase_GDSL_2 PF13472.6 EIM80236.1 - 1.1e-12 48.7 0.4 2.4e-12 47.6 0.4 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIM80236.1 - 3.6e-07 30.4 0.1 6.4e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2975 PF11188.8 EIM80237.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF202 PF02656.15 EIM80237.1 - 0.085 13.3 0.2 0.19 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) F-box-like PF12937.7 EIM80238.1 - 1.3e-09 37.7 1.3 3.5e-09 36.4 1.3 1.8 1 0 0 1 1 1 1 F-box-like DDE_3 PF13358.6 EIM80238.1 - 0.066 13.0 0.1 0.86 9.4 0.1 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease LRR_4 PF12799.7 EIM80238.1 - 0.31 11.5 2.1 40 4.8 0.1 3.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) YcbB PF08664.10 EIM80239.1 - 0.0068 16.5 2.6 1.8 8.6 0.0 2.2 2 0 0 2 2 2 2 YcbB domain STAG PF08514.11 EIM80239.1 - 0.79 9.7 4.0 1.4 8.9 4.0 1.4 1 0 0 1 1 1 0 STAG domain HSDR_N_2 PF13588.6 EIM80240.1 - 0.022 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Uma2 PF05685.12 EIM80240.1 - 0.11 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative restriction endonuclease Methyltransf_25 PF13649.6 EIM80241.1 - 3.3e-11 43.7 0.0 7.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM80241.1 - 1.5e-09 38.4 0.0 2.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM80241.1 - 8e-09 35.5 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM80241.1 - 1.3e-08 34.8 0.0 3.3e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM80241.1 - 6.5e-06 26.8 0.0 2.1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EIM80241.1 - 4.9e-05 23.5 0.0 0.00015 21.9 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EIM80241.1 - 9.7e-05 21.9 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 EIM80241.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain RNR_inhib PF08591.10 EIM80241.1 - 0.091 14.1 1.8 0.23 12.8 0.1 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor MTS PF05175.14 EIM80241.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain TPR_10 PF13374.6 EIM80242.1 - 3.7e-09 36.2 11.7 0.23 11.4 0.0 10.0 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIM80242.1 - 1.9e-08 33.7 1.5 0.53 10.4 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat Formin_GBD_N PF18382.1 EIM80242.1 - 4.2e-07 30.3 1.5 0.99 9.9 0.1 4.9 4 1 1 5 5 5 3 Formin N-terminal GTPase-binding domain TPR_12 PF13424.6 EIM80242.1 - 5.6e-06 26.6 15.5 1.7 9.0 0.1 8.2 5 3 5 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM80242.1 - 0.00048 19.8 11.6 2.8 7.7 0.0 8.3 10 0 0 10 10 10 1 TPR repeat TPR_2 PF07719.17 EIM80242.1 - 0.0059 16.6 2.4 1.1e+02 3.3 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 EIM80242.1 - 0.038 14.2 0.9 58 4.0 0.0 4.7 6 0 0 6 6 6 0 MIT domain of nuclear receptor-binding factor 2 DUF2025 PF09634.10 EIM80242.1 - 0.078 13.0 0.4 41 4.3 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2025) Spermine_synt_N PF17284.2 EIM80242.1 - 0.15 12.0 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Spermidine synthase tetramerisation domain Bacillus_PapR PF05968.11 EIM80242.1 - 0.36 10.7 11.2 20 5.1 0.1 5.2 5 0 0 5 5 5 0 Bacillus PapR protein TPR_14 PF13428.6 EIM80242.1 - 0.75 10.8 7.9 21 6.3 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat HNH_2 PF13391.6 EIM80242.1 - 8.3 6.6 8.6 80 3.5 0.0 4.9 5 2 0 5 5 5 0 HNH endonuclease La PF05383.17 EIM80243.1 - 3e-20 72.0 0.0 6.3e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EIM80243.1 - 3.9e-08 33.0 0.2 8.8e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 EIM80244.1 - 1.5e-06 27.9 0.4 3.9e-06 26.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like AMPKBI PF04739.15 EIM80244.1 - 0.026 14.8 2.1 4.5 7.6 0.1 2.9 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain Fungal_trans PF04082.18 EIM80246.1 - 2.2e-10 40.0 0.0 3.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM80246.1 - 0.0025 17.9 8.1 0.0042 17.2 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EIM80249.1 - 2.3e-07 30.6 0.4 5.4e-07 29.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like FlxA PF14282.6 EIM80249.1 - 0.24 11.4 0.3 0.44 10.6 0.3 1.3 1 0 0 1 1 1 0 FlxA-like protein AMPKBI PF04739.15 EIM80249.1 - 2.3 8.6 7.6 1.9 8.8 0.1 2.8 3 0 0 3 3 3 0 5'-AMP-activated protein kinase beta subunit, interaction domain Tyr-DNA_phospho PF06087.12 EIM80250.1 - 1.3e-47 162.6 0.0 1.9e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EIM80250.1 - 0.061 13.2 0.0 7.1 6.5 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain UIM PF02809.20 EIM80250.1 - 4.1 7.5 14.5 0.74 9.9 0.7 3.2 3 1 1 4 4 4 0 Ubiquitin interaction motif Peroxin-3 PF04882.12 EIM80250.1 - 5.3 5.9 5.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Peroxin-3 Aconitase PF00330.20 EIM80251.1 - 4.7e-154 513.8 0.0 5.9e-154 513.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIM80251.1 - 6.4e-44 149.5 0.0 1.1e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Importin_rep PF18773.1 EIM80255.1 - 4.3e-09 35.9 0.0 9.7e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 EIM80255.1 - 1.6e-05 24.8 0.0 4.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 EIM80255.1 - 0.0023 17.8 0.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain SSP160 PF06933.11 EIM80255.1 - 0.042 12.1 2.9 0.067 11.4 2.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WD40 PF00400.32 EIM80256.1 - 2.1e-23 82.2 15.7 5.3e-09 36.6 0.2 5.4 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM80256.1 - 7.3e-09 35.8 0.0 0.0018 18.5 0.0 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM80256.1 - 0.014 14.1 0.3 0.97 8.0 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM80256.1 - 0.25 10.6 0.0 0.51 9.6 0.0 1.4 1 1 0 1 1 1 0 WD40-like domain ADH_zinc_N PF00107.26 EIM80257.1 - 2.4e-23 82.5 0.0 3.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM80257.1 - 7.8e-20 72.3 0.0 1.7e-19 71.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM80257.1 - 1.6e-12 47.3 0.2 2.9e-11 43.2 0.2 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 EIM80258.1 - 3.2e-47 161.3 0.0 1.7e-46 159.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_3 PF13302.7 EIM80260.1 - 4e-17 63.2 0.0 4.9e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80260.1 - 4.6e-12 46.2 0.0 5.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EIM80260.1 - 4.7e-11 43.1 0.0 5.5e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM80260.1 - 1.2e-06 28.8 0.1 1.8e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM80260.1 - 0.0062 16.5 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM80260.1 - 0.0067 16.4 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EIM80260.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SBE2 PF17076.5 EIM80260.1 - 0.056 11.7 0.0 0.071 11.3 0.0 1.0 1 0 0 1 1 1 0 SBE2, cell-wall formation NAD_binding_4 PF07993.12 EIM80261.1 - 1.3e-22 80.2 0.0 2.7e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM80261.1 - 1.4e-12 46.9 0.0 2.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM80261.1 - 6.3e-07 29.1 0.0 9.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF240 PF03086.14 EIM80261.1 - 0.08 12.9 0.1 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF240) dCMP_cyt_deam_1 PF00383.23 EIM80265.1 - 7.9e-17 61.0 0.1 9.7e-17 60.7 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EIM80265.1 - 2.8e-13 50.2 3.1 6.7e-12 45.8 0.5 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EIM80265.1 - 0.017 14.8 1.2 0.24 11.0 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases DUF4360 PF14273.6 EIM80265.1 - 0.14 12.1 0.1 0.18 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) FAD_binding_3 PF01494.19 EIM80266.1 - 2.7e-15 56.5 0.0 5.7e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM80266.1 - 2.7e-06 27.5 0.5 6.9e-06 26.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM80266.1 - 5.2e-06 25.8 0.8 9.4e-06 25.0 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM80266.1 - 5.3e-05 23.0 2.6 0.00053 19.7 3.6 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM80266.1 - 0.00058 19.2 0.3 0.0011 18.3 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EIM80266.1 - 0.00096 18.5 0.5 0.0014 17.9 0.5 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM80266.1 - 0.004 16.1 0.5 0.0071 15.2 0.2 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EIM80266.1 - 0.0063 15.8 0.3 0.011 15.0 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM80266.1 - 0.0093 14.7 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EIM80266.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM80266.1 - 0.11 13.1 0.4 0.28 11.8 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM80266.1 - 0.23 10.5 3.2 0.18 10.8 1.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A SelP_N PF04592.14 EIM80269.1 - 0.18 11.2 12.7 0.2 11.1 12.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mak10 PF04112.13 EIM80269.1 - 0.27 10.7 3.1 0.29 10.6 3.1 1.2 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Polyoma_coat2 PF00761.20 EIM80269.1 - 0.47 10.1 7.1 0.56 9.9 7.1 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein DUF4834 PF16118.5 EIM80269.1 - 1.3 10.0 6.2 1.7 9.7 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 EIM80269.1 - 1.7 7.3 4.0 1.6 7.4 4.0 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EIM80269.1 - 4.1 7.3 19.3 4.5 7.2 19.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cupin_2 PF07883.11 EIM80271.1 - 8.2e-06 25.5 0.2 3.9e-05 23.3 0.4 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EIM80271.1 - 0.0078 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Med3 PF11593.8 EIM80272.1 - 2.9 7.0 11.0 4.2 6.5 11.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FSA_C PF10479.9 EIM80272.1 - 3 5.9 13.6 3.8 5.5 13.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FSA_C PF10479.9 EIM80273.1 - 8.4 4.4 11.4 13 3.8 11.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3825 PF12873.7 EIM80275.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) zf-MYND PF01753.18 EIM80276.1 - 1.5e-07 31.4 16.1 2.9e-07 30.4 16.1 1.5 1 0 0 1 1 1 1 MYND finger Ribonuc_red_lgC PF02867.15 EIM80277.1 - 1.3e-182 608.0 0.0 6.8e-182 605.6 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EIM80277.1 - 2.9e-20 72.0 0.0 7.1e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EIM80277.1 - 5.8e-14 52.4 0.1 1.4e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 ATP cone domain Peptidase_S28 PF05577.12 EIM80278.1 - 1.9e-60 204.9 0.7 1.5e-59 202.0 0.7 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 GMC_oxred_N PF00732.19 EIM80279.1 - 1.8e-60 204.8 0.2 2.5e-60 204.4 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM80279.1 - 8.2e-32 110.7 0.0 1.5e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM80279.1 - 0.00026 21.2 0.1 0.0006 20.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM80279.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM80279.1 - 0.014 14.5 0.3 0.047 12.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EIM80279.1 - 0.037 13.6 0.8 0.059 12.9 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM80279.1 - 0.048 12.9 0.1 0.37 10.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EIM80279.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain PNGaseA PF12222.8 EIM80280.1 - 6.5e-111 371.3 1.9 9.1e-111 370.8 1.9 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Sortilin-Vps10 PF15902.5 EIM80281.1 - 5.6e-291 964.8 0.3 2.9e-150 501.0 0.0 2.3 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EIM80281.1 - 5.2e-95 316.6 14.1 1e-51 175.6 3.0 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EIM80281.1 - 7.1e-12 43.5 39.4 1.5 9.1 0.4 12.2 11 0 0 11 11 11 6 BNR/Asp-box repeat BNR_2 PF13088.6 EIM80281.1 - 7.6e-05 22.1 3.7 0.98 8.7 0.0 5.4 5 1 1 6 6 6 1 BNR repeat-like domain PSII_BNR PF14870.6 EIM80281.1 - 0.00048 19.5 0.2 11 5.2 0.0 4.4 4 0 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 EIM80281.1 - 0.0034 17.3 7.7 5.1 7.1 0.0 5.3 6 0 0 6 6 6 2 Chitobiase/beta-hexosaminidase C-terminal domain BNR_6 PF15899.5 EIM80281.1 - 0.0047 16.9 1.7 8.5 6.8 0.0 4.3 3 0 0 3 3 3 2 BNR-Asp box repeat Fe_dep_repr_C PF02742.15 EIM80281.1 - 0.017 15.2 0.0 0.31 11.1 0.0 2.9 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain SHS2_Rpb7-N PF03876.17 EIM80282.1 - 3e-15 56.3 0.0 4.8e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EIM80282.1 - 1.6e-11 44.4 0.2 2.9e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EIM80282.1 - 0.0064 16.7 0.1 0.0098 16.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Med3 PF11593.8 EIM80283.1 - 2.6 7.2 5.9 4.5 6.4 5.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pox_Ag35 PF03286.14 EIM80290.1 - 2.6 7.8 7.9 1.6 8.5 4.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein WD40 PF00400.32 EIM80293.1 - 7.2e-35 118.4 30.8 3.2e-07 30.9 0.3 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM80293.1 - 4.8e-13 49.2 2.8 0.00072 19.8 0.0 5.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EIM80293.1 - 1.2e-10 41.1 0.4 1.2e-10 41.1 0.4 1.9 2 0 0 2 2 2 1 F-box-like WD40_like PF17005.5 EIM80293.1 - 2e-08 33.9 0.0 0.0039 16.6 0.0 3.4 2 1 2 4 4 4 3 WD40-like domain Nup160 PF11715.8 EIM80293.1 - 4.3e-05 22.3 2.3 0.18 10.4 0.1 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 DUF5046 PF16465.5 EIM80293.1 - 0.011 15.2 0.0 0.17 11.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) F-box PF00646.33 EIM80293.1 - 0.017 15.0 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain PQQ_3 PF13570.6 EIM80293.1 - 0.11 13.0 9.3 11 6.7 0.1 5.2 6 1 0 6 6 6 0 PQQ-like domain Nucleoporin_N PF08801.11 EIM80293.1 - 0.25 10.1 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like zf-C2H2 PF00096.26 EIM80297.1 - 0.0045 17.4 9.9 0.12 12.9 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM80297.1 - 0.73 10.8 7.4 2.9 9.0 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYND PF01753.18 EIM80298.1 - 2.6e-09 37.0 14.6 6.3e-09 35.8 14.6 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 EIM80299.1 - 3.4e-08 33.4 18.3 3.4e-08 33.4 18.3 2.3 2 0 0 2 2 2 1 MYND finger Abhydrolase_1 PF00561.20 EIM80300.1 - 3.8e-14 52.9 0.0 9.4e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM80300.1 - 5.7e-10 40.2 0.1 6.9e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM80300.1 - 2.7e-07 30.1 0.0 6.2e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EIM80300.1 - 0.00012 22.3 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain GDI PF00996.18 EIM80300.1 - 0.059 11.9 0.0 0.083 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DLH PF01738.18 EIM80300.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family CKS PF01111.19 EIM80302.1 - 0.043 14.1 0.1 0.081 13.2 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit Abhydrolase_1 PF00561.20 EIM80303.1 - 2.5e-22 79.8 0.0 6.3e-22 78.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM80303.1 - 5.1e-14 52.1 0.0 3.9e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM80303.1 - 6.3e-12 46.6 0.0 7.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EIM80303.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EIM80303.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 EIM80303.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EIM80306.1 - 4.3e-23 81.7 0.1 5.8e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 EIM80306.1 - 0.0032 17.0 0.1 0.0046 16.5 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EIM80306.1 - 0.057 14.0 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family He_PIG PF05345.12 EIM80307.1 - 0.0016 18.6 0.1 0.0036 17.5 0.1 1.6 1 0 0 1 1 1 1 Putative Ig domain Homeodomain PF00046.29 EIM80310.1 - 1.7e-10 40.6 0.3 3.5e-10 39.6 0.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EIM80310.1 - 0.00057 19.7 0.3 0.0013 18.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 EIM80310.1 - 0.13 12.2 0.1 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MAP65_ASE1 PF03999.12 EIM80311.1 - 0.46 9.1 8.5 1 8.0 8.5 1.5 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MAP70 PF07058.11 EIM80311.1 - 4.4 5.9 5.4 6.2 5.4 5.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 zf-MYND PF01753.18 EIM80312.1 - 6.2e-08 32.6 17.2 1.9e-07 31.0 17.2 1.9 1 0 0 1 1 1 1 MYND finger NAD_binding_4 PF07993.12 EIM80314.1 - 1e-29 103.5 0.0 2.5e-29 102.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EIM80314.1 - 8.5e-28 97.1 0.0 6.9e-27 94.1 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM80314.1 - 7.1e-09 35.5 0.0 1.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM80314.1 - 0.0013 18.3 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 EIM80314.1 - 0.0026 18.1 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EIM80314.1 - 0.0027 16.7 0.0 0.0064 15.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PS_Dcarbxylase PF02666.15 EIM80315.1 - 3.7e-49 167.0 0.0 5.1e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase F-box-like PF12937.7 EIM80317.1 - 7.3e-05 22.6 4.3 8.7e-05 22.3 1.2 2.8 2 1 0 2 2 2 1 F-box-like Se-cys_synth_N PF12390.8 EIM80317.1 - 0.002 18.3 0.0 0.021 15.0 0.0 2.5 1 1 0 1 1 1 1 Selenocysteine synthase N terminal TPR_1 PF00515.28 EIM80318.1 - 1.4e-34 116.5 0.0 4.7e-05 23.0 0.0 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 EIM80318.1 - 5.2e-30 101.1 6.9 0.0015 18.5 0.0 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 EIM80318.1 - 1.6e-20 73.5 17.7 5.4e-08 33.4 0.4 5.8 4 1 2 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.31 EIM80318.1 - 3.1e-20 72.1 0.1 6e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 EIM80318.1 - 2.7e-19 68.6 3.7 3.5e-06 26.6 0.0 6.7 5 1 1 6 6 6 4 TPR repeat TPR_12 PF13424.6 EIM80318.1 - 1.2e-16 60.8 18.0 8.5e-05 22.8 0.4 6.3 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 EIM80318.1 - 2.3e-15 56.5 15.2 6.6e-06 26.2 0.1 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIM80318.1 - 1.2e-13 50.6 22.2 0.084 13.7 0.0 8.6 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EIM80318.1 - 1e-11 45.1 23.3 0.00036 21.0 0.5 6.1 4 3 2 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM80318.1 - 4.5e-10 38.9 0.7 0.054 13.7 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM80318.1 - 2.8e-09 36.4 5.1 0.033 14.2 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIM80318.1 - 5.4e-09 35.8 8.2 0.059 13.8 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM80318.1 - 2.9e-08 33.8 5.2 0.18 12.0 0.0 4.8 3 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EIM80318.1 - 1e-06 28.9 1.9 0.063 13.9 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM80318.1 - 4.9e-06 26.5 5.7 0.012 15.6 0.1 5.2 5 1 1 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EIM80318.1 - 5.5e-05 23.1 0.6 0.37 10.9 0.0 4.2 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain DEC-1_N PF04625.13 EIM80318.1 - 0.00018 20.7 2.2 0.00023 20.3 2.2 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Coatomer_E PF04733.14 EIM80318.1 - 0.00036 20.0 3.6 0.071 12.5 0.0 3.1 3 0 0 3 3 3 1 Coatomer epsilon subunit TPR_15 PF13429.6 EIM80318.1 - 0.0014 17.9 10.6 0.1 11.8 0.6 4.2 3 2 2 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EIM80318.1 - 0.0071 15.8 3.4 6.8 6.2 0.0 5.0 5 0 0 5 5 5 1 SHNi-TPR Alkyl_sulf_dimr PF14863.6 EIM80318.1 - 0.14 12.6 0.6 1.8 9.0 0.0 2.8 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 EIM80318.1 - 0.18 12.6 13.0 5.1 8.0 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat F-box-like PF12937.7 EIM80320.1 - 7.2e-07 29.0 1.4 2e-06 27.6 0.1 2.5 2 1 0 2 2 2 1 F-box-like SH3_9 PF14604.6 EIM80321.1 - 3e-30 103.8 2.0 4.9e-16 58.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EIM80321.1 - 6.2e-27 93.0 2.9 5.2e-14 51.6 0.3 2.6 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 EIM80321.1 - 4.2e-23 81.4 0.0 7.4e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EIM80321.1 - 2.3e-17 62.4 0.2 7.4e-10 38.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Trypan_PARP PF05887.11 EIM80321.1 - 0.0041 17.1 21.6 0.0041 17.1 21.6 4.5 3 1 1 4 4 4 1 Procyclic acidic repetitive protein (PARP) MliC PF09864.9 EIM80321.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme WD40 PF00400.32 EIM80322.1 - 4.8e-105 340.5 48.7 4.2e-10 40.1 0.1 14.6 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM80322.1 - 2.7e-38 130.1 1.1 0.003 17.8 0.0 12.3 2 2 10 12 12 12 9 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM80322.1 - 3.9e-11 42.3 0.7 0.083 11.5 0.0 7.5 6 3 2 9 9 9 2 Nucleoporin Nup120/160 AAA_16 PF13191.6 EIM80322.1 - 3.2e-10 40.7 0.5 1e-09 39.0 0.1 2.1 2 0 0 2 2 1 1 AAA ATPase domain Ge1_WD40 PF16529.5 EIM80322.1 - 9.6e-10 37.9 4.2 0.5 9.3 0.0 8.7 5 4 4 10 10 10 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 EIM80322.1 - 9.8e-08 32.1 0.0 2.9e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 EIM80322.1 - 7.9e-07 28.9 14.1 27 4.9 0.0 10.6 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EIM80322.1 - 1.3e-06 28.0 0.0 8.8 5.5 0.0 6.9 6 1 2 8 8 8 1 WD40-like domain Gmad1 PF10647.9 EIM80322.1 - 4e-06 26.8 10.1 0.42 10.3 0.1 7.0 2 2 3 6 6 6 2 Lipoprotein LpqB beta-propeller domain AAA_22 PF13401.6 EIM80322.1 - 3e-05 24.3 0.0 9.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain C2 PF00168.30 EIM80322.1 - 0.00075 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain ATPase_2 PF01637.18 EIM80322.1 - 0.0011 19.0 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EIM80322.1 - 0.0069 16.8 0.0 0.027 14.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM80322.1 - 0.0089 16.0 0.1 2.3 8.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EIM80322.1 - 0.021 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Frtz PF11768.8 EIM80322.1 - 0.025 12.9 0.0 32 2.7 0.0 4.8 6 1 2 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 EIM80322.1 - 0.03 14.8 2.0 69 4.1 0.1 5.0 4 1 1 5 5 4 0 PQQ-like domain KAP_NTPase PF07693.14 EIM80322.1 - 0.058 12.6 0.8 1.2 8.3 0.1 2.5 2 1 0 3 3 3 0 KAP family P-loop domain Zeta_toxin PF06414.12 EIM80322.1 - 0.079 12.2 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EIM80322.1 - 0.18 12.4 0.0 0.81 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain ICEA PF05315.11 EIM80324.1 - 0.19 11.1 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 ICEA Protein Aldo_ket_red PF00248.21 EIM80326.1 - 3.2e-66 223.5 0.0 3.6e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 EIM80327.1 - 1.5e-52 179.0 0.0 3.2e-52 177.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EIM80327.1 - 8.4e-07 28.5 0.3 1.9e-06 27.4 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EIM80327.1 - 8e-05 22.9 0.9 0.00019 21.7 0.2 1.9 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 EIM80327.1 - 8.3e-05 22.0 1.7 0.012 14.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM80327.1 - 0.0001 22.0 0.2 0.0051 16.4 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM80327.1 - 0.00012 21.3 0.3 0.0026 16.9 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein F420_oxidored PF03807.17 EIM80327.1 - 0.00053 20.5 0.1 0.001 19.6 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 EIM80327.1 - 0.0016 17.4 0.6 0.16 10.8 0.0 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 EIM80327.1 - 0.0023 18.5 0.3 0.19 12.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM80327.1 - 0.0035 17.5 0.1 0.0091 16.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EIM80327.1 - 0.0054 16.3 0.1 0.13 11.9 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 EIM80327.1 - 0.007 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EIM80327.1 - 0.012 14.8 0.2 0.024 13.7 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EIM80327.1 - 0.013 14.9 0.4 0.042 13.2 0.4 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM80327.1 - 0.053 12.2 0.4 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.21 EIM80327.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 EIM80327.1 - 0.2 11.0 0.3 0.46 9.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EIM80327.1 - 0.21 10.6 1.1 0.42 9.6 1.1 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Peptidase_M54 PF07998.11 EIM80328.1 - 2.8e-06 27.5 0.2 5.1e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_4 PF13583.6 EIM80328.1 - 0.13 11.9 0.2 0.24 11.0 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EIM80328.1 - 0.14 12.3 0.3 0.24 11.5 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EIM80328.1 - 0.2 12.2 0.1 0.47 11.0 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EIM80328.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 EIM80328.1 - 0.24 11.0 0.3 0.43 10.2 0.3 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase RNase_H2_suC PF08615.11 EIM80329.1 - 1.1e-22 80.7 0.0 1.7e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Caprin-1_C PF12287.8 EIM80329.1 - 2.3 8.3 8.5 3.1 7.9 8.5 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term PRCC PF10253.9 EIM80329.1 - 5.7 7.7 9.6 14 6.4 9.6 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting GPI-anchored PF10342.9 EIM80330.1 - 2.3e-09 37.9 1.3 2.3e-09 37.9 1.3 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNA_pol_Rpc4 PF05132.14 EIM80330.1 - 0.21 12.0 2.0 0.36 11.3 0.9 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Macoilin PF09726.9 EIM80330.1 - 4.1 5.8 9.7 5.3 5.5 9.7 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EIM80330.1 - 5.7 5.7 7.8 7.3 5.3 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-MYND PF01753.18 EIM80331.1 - 6.3e-10 39.0 16.7 1.2e-09 38.1 16.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EIM80331.1 - 0.002 18.2 5.4 0.0066 16.5 5.4 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EIM80331.1 - 0.015 15.6 12.4 0.027 14.8 12.4 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 EIM80331.1 - 4.3 7.3 9.3 12 5.9 9.3 1.7 1 0 0 1 1 1 0 HIT zinc finger UBX PF00789.20 EIM80332.1 - 5e-12 45.9 0.4 1.3e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 EIM80332.1 - 1.3e-05 25.0 0.0 1.3e-05 25.0 0.0 2.9 3 1 0 3 3 3 1 UBA/TS-N domain Mitofilin PF09731.9 EIM80332.1 - 0.012 14.5 20.4 0.014 14.3 20.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-C2H2 PF00096.26 EIM80332.1 - 0.11 13.0 0.2 0.2 12.2 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EIM80332.1 - 0.32 11.3 4.1 0.21 12.0 1.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rtf2 PF04641.12 EIM80332.1 - 3.1 7.1 26.9 12 5.1 26.9 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger SOBP PF15279.6 EIM80332.1 - 4.6 7.8 5.2 6.9 7.2 5.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CpXC PF14353.6 EIM80332.1 - 7.2 6.7 6.7 33 4.6 6.8 2.1 1 1 0 1 1 1 0 CpXC protein FAD_binding_3 PF01494.19 EIM80333.1 - 3e-41 141.8 0.6 1.7e-25 90.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EIM80333.1 - 1.3e-05 24.6 0.0 5.6e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM80333.1 - 0.00083 19.0 0.1 0.002 17.8 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM80333.1 - 0.0025 16.9 0.2 0.0045 16.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM80333.1 - 0.018 14.3 0.3 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EIM80333.1 - 0.026 14.9 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EIM80333.1 - 0.047 14.2 0.2 5.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EIM80333.1 - 0.051 13.8 0.1 0.097 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EIM80333.1 - 0.09 12.8 0.1 0.22 11.6 0.1 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EIM80333.1 - 0.11 11.8 0.3 0.41 10.0 0.3 1.8 1 1 1 2 2 2 0 ThiF family HI0933_like PF03486.14 EIM80333.1 - 0.15 10.7 0.2 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.10 EIM80333.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Ldh_1_N PF00056.23 EIM80333.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EIM80333.1 - 0.74 8.8 3.8 1.9 7.4 0.9 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein DUF3328 PF11807.8 EIM80335.1 - 1.6e-13 51.0 0.3 2.2e-13 50.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EIM80336.1 - 4.1e-16 59.4 3.1 3.7e-15 56.3 3.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_10 PF13673.7 EIM80337.1 - 2.4e-07 30.7 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM80337.1 - 0.00028 21.3 0.0 0.00044 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM80337.1 - 0.0007 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80337.1 - 0.0012 19.1 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EIM80337.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF4064 PF13273.6 EIM80338.1 - 1.1 9.5 7.5 0.54 10.6 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Oxidored_q3 PF00499.20 EIM80338.1 - 1.8 8.2 13.1 0.61 9.8 8.2 2.1 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 zf-HC5HC2H_2 PF13832.6 EIM80339.1 - 1.3e-31 109.0 14.0 4.2e-31 107.3 8.7 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EIM80339.1 - 1.3e-23 84.1 1.3 1.3e-23 84.1 1.3 3.6 4 0 0 4 4 4 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EIM80339.1 - 1.6e-23 82.7 12.5 5e-23 81.2 5.8 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 EIM80339.1 - 2.2e-20 72.5 0.2 5.5e-20 71.2 0.2 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 EIM80339.1 - 5e-15 54.8 2.6 5e-15 54.8 2.6 2.8 3 0 0 3 3 2 2 PHD-finger PWWP PF00855.17 EIM80339.1 - 2.6e-14 53.4 0.2 7.6e-14 51.9 0.2 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 EIM80339.1 - 2.5e-10 40.1 5.3 2.5e-10 40.1 5.3 2.9 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.6 EIM80339.1 - 0.0063 16.1 0.4 0.0063 16.1 0.4 2.6 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EIM80339.1 - 0.018 14.9 0.3 0.018 14.9 0.3 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EIM80339.1 - 0.53 10.6 14.9 0.17 12.2 0.8 2.8 3 0 0 3 3 2 0 C1 domain FYVE_2 PF02318.16 EIM80339.1 - 2.3 8.4 8.0 0.08 13.2 0.4 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4470 PF14737.6 EIM80340.1 - 2.1e-23 82.3 0.1 4.2e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EIM80340.1 - 1.2e-08 34.9 11.5 2.7e-08 33.8 11.5 1.5 1 0 0 1 1 1 1 MYND finger RGI1 PF10843.8 EIM80341.1 - 0.0042 16.8 0.1 0.0075 15.9 0.1 1.3 1 0 0 1 1 1 1 Respiratory growth induced protein 1 Thioredoxin PF00085.20 EIM80342.1 - 1.8e-19 69.6 0.1 9.5e-19 67.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EIM80342.1 - 5.6e-05 23.5 0.0 0.00017 22.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIM80342.1 - 0.035 14.4 0.0 3.2 8.1 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EIM80342.1 - 0.05 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EIM80342.1 - 0.077 12.8 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin YbbR PF07949.12 EIM80342.1 - 0.15 12.4 0.5 0.3 11.4 0.5 1.5 1 0 0 1 1 1 0 YbbR-like protein DUF966 PF06136.13 EIM80342.1 - 0.25 11.0 6.9 0.4 10.4 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hist_deacetyl PF00850.19 EIM80343.1 - 1.4e-85 287.5 0.0 6.1e-85 285.4 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.9 EIM80343.1 - 1.7e-37 129.0 0.2 2.4e-37 128.5 0.2 1.1 1 0 0 1 1 1 1 Arb2 domain F-box-like PF12937.7 EIM80344.1 - 6.2e-07 29.2 0.3 1.2e-06 28.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like LRR_9 PF14580.6 EIM80344.1 - 0.00071 19.1 0.8 0.002 17.7 0.1 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EIM80344.1 - 0.041 14.3 6.1 25 5.4 0.0 5.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) STT3 PF02516.14 EIM80345.1 - 2.4e-145 485.2 30.0 4.9e-139 464.4 26.6 2.4 2 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Band_7 PF01145.25 EIM80346.1 - 5e-23 82.0 0.0 1.1e-22 80.8 0.0 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family POX PF07526.11 EIM80347.1 - 1.8 9.2 3.6 6.7 7.3 3.6 2.3 1 1 0 1 1 1 0 Associated with HOX DDE_Tnp_4 PF13359.6 EIM80348.1 - 1.5e-23 83.2 0.0 2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC_membrane PF00664.23 EIM80350.1 - 8.2e-53 179.8 34.5 1.1e-31 110.5 11.7 3.6 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 EIM80350.1 - 4.1e-45 153.7 0.0 6.8e-28 97.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM80350.1 - 1.8e-11 43.9 5.2 0.0021 17.5 0.7 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIM80350.1 - 9.2e-07 29.6 0.5 0.00063 20.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIM80350.1 - 1e-05 25.2 0.3 0.13 11.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EIM80350.1 - 2e-05 24.6 2.0 0.035 13.9 0.0 3.6 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EIM80350.1 - 2.5e-05 24.7 0.1 0.18 12.2 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EIM80350.1 - 8.3e-05 22.3 0.1 0.54 10.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIM80350.1 - 0.00011 22.2 0.1 0.23 11.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM80350.1 - 0.00058 19.8 0.2 0.63 9.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 EIM80350.1 - 0.0011 18.7 0.8 1.9 8.2 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein T2SSE PF00437.20 EIM80350.1 - 0.0013 17.9 0.0 0.51 9.4 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 EIM80350.1 - 0.0017 17.2 0.1 0.031 13.1 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA PF00004.29 EIM80350.1 - 0.0023 18.4 0.4 0.25 11.8 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIM80350.1 - 0.0037 16.8 0.9 0.41 10.1 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_22 PF13401.6 EIM80350.1 - 0.0039 17.5 0.2 2.9 8.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EIM80350.1 - 0.0045 17.0 0.6 4 7.4 0.1 3.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EIM80350.1 - 0.008 16.3 0.5 0.094 12.8 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 EIM80350.1 - 0.016 15.0 0.1 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Phage_holin_2_4 PF16082.5 EIM80350.1 - 0.022 14.5 0.6 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like FtsK_SpoIIIE PF01580.18 EIM80350.1 - 0.043 13.2 0.1 7.2 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 EIM80350.1 - 0.044 14.3 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain SEO_N PF14576.6 EIM80350.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Sieve element occlusion N-terminus RNA_helicase PF00910.22 EIM80350.1 - 0.09 13.2 0.0 9.6 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 EIM80350.1 - 0.11 11.9 0.1 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 EIM80350.1 - 0.13 12.2 0.6 0.75 9.7 0.0 2.4 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 EIM80350.1 - 0.18 11.9 1.1 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.9 EIM80350.1 - 0.19 11.5 1.9 5 6.9 0.1 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 EIM80350.1 - 0.19 11.7 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EIM80350.1 - 0.52 10.0 2.6 11 5.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain DUF3272 PF11676.8 EIM80350.1 - 0.52 10.6 3.9 18 5.7 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) MobB PF03205.14 EIM80350.1 - 1.5 8.7 3.6 27 4.7 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF5368 PF17336.2 EIM80350.1 - 3.1 8.0 9.1 0.13 12.5 0.3 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5368) F-box-like PF12937.7 EIM80351.1 - 1.6e-05 24.7 2.5 3.1e-05 23.8 2.5 1.5 1 0 0 1 1 1 1 F-box-like DNA_pol_delta_4 PF04081.13 EIM80352.1 - 2e-32 112.3 0.8 3e-32 111.7 0.4 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Rota_VP2 PF05087.12 EIM80352.1 - 0.4 8.8 1.2 0.49 8.5 1.2 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein FAD_binding_3 PF01494.19 EIM80353.1 - 2.3e-76 257.3 0.0 6.7e-76 255.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM80353.1 - 4.5e-29 101.6 0.0 9.4e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EIM80353.1 - 1.4e-05 24.0 1.4 2e-05 23.5 1.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM80353.1 - 1.8e-05 24.1 0.5 4.8e-05 22.7 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM80353.1 - 5.3e-05 23.4 0.1 0.00015 21.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM80353.1 - 7.8e-05 21.9 1.9 0.00011 21.4 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EIM80353.1 - 0.00043 19.6 0.4 0.0008 18.8 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EIM80353.1 - 0.00055 19.4 2.7 0.00087 18.7 2.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EIM80353.1 - 0.00064 19.4 1.2 0.019 14.5 0.7 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIM80353.1 - 0.001 18.1 1.4 0.006 15.5 0.5 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EIM80353.1 - 0.0012 18.1 0.4 0.0019 17.5 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM80353.1 - 0.0013 17.9 0.9 0.0023 17.1 0.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EIM80353.1 - 0.003 18.1 0.2 0.0075 16.8 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM80353.1 - 0.0045 16.3 0.2 0.0085 15.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EIM80353.1 - 0.018 14.1 1.2 0.031 13.3 1.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EIM80353.1 - 0.026 14.4 0.2 0.046 13.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EIM80353.1 - 0.031 13.9 0.1 0.07 12.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EIM80353.1 - 0.038 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EIM80353.1 - 0.054 13.8 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_9 PF13454.6 EIM80353.1 - 0.073 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.6 EIM80353.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain DUF498 PF04430.14 EIM80353.1 - 0.12 12.4 0.0 4.3 7.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) ThiF PF00899.21 EIM80353.1 - 0.16 11.3 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EIM80353.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37 PF08561.10 EIM80354.1 - 0.012 16.2 1.3 0.019 15.5 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 TPR_MLP1_2 PF07926.12 EIM80354.1 - 0.036 14.1 4.1 0.059 13.4 4.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3987 PF13148.6 EIM80354.1 - 0.049 12.6 1.5 0.071 12.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CLZ PF16526.5 EIM80354.1 - 0.062 13.7 1.3 0.062 13.7 1.3 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CdvA PF18822.1 EIM80354.1 - 0.062 13.1 8.2 0.04 13.7 5.1 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain FliT PF05400.13 EIM80354.1 - 0.64 10.9 9.0 1.3 9.9 9.0 1.5 1 0 0 1 1 1 0 Flagellar protein FliT ABC_tran_CTD PF16326.5 EIM80354.1 - 1.7 9.0 8.3 3.2 8.1 8.3 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain Amidohydro_1 PF01979.20 EIM80355.1 - 1.3e-24 87.2 0.0 4e-23 82.3 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM80355.1 - 7.7e-18 65.2 0.3 1.9e-07 31.0 0.0 3.6 4 0 0 4 4 4 2 Amidohydrolase family Urease_alpha PF00449.20 EIM80355.1 - 0.0083 16.5 0.3 0.022 15.1 0.3 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Motile_Sperm PF00635.26 EIM80355.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 MSP (Major sperm protein) domain CN_hydrolase PF00795.22 EIM80356.1 - 2.5e-37 128.6 0.0 3.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Zn_clus PF00172.18 EIM80357.1 - 0.00021 21.3 9.3 0.00035 20.6 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIM80357.1 - 0.00024 20.2 0.1 0.00024 20.2 0.1 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain DAO PF01266.24 EIM80358.1 - 3.9e-25 89.2 0.2 8.8e-25 88.0 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EIM80358.1 - 0.03 14.8 0.0 0.05 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EIM80358.1 - 0.066 12.9 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Transport_MerF PF11431.8 EIM80358.1 - 0.3 11.0 0.9 0.58 10.1 0.9 1.5 1 0 0 1 1 1 0 Membrane transport protein MerF Asp_Glu_race PF01177.22 EIM80359.1 - 3.5e-08 33.6 0.0 4.5e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Transp_cyt_pur PF02133.15 EIM80360.1 - 6.2e-108 361.4 40.3 7.3e-108 361.2 40.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1270 PF06900.11 EIM80360.1 - 4.4 7.7 6.6 69 3.9 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) Aldolase_II PF00596.21 EIM80361.1 - 9.9e-45 152.8 0.0 1.3e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain p450 PF00067.22 EIM80362.1 - 7.6e-69 232.6 0.0 1.2e-68 231.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM80363.1 - 2.9e-70 237.3 0.0 7.8e-70 235.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Glycos_transf_2 PF00535.26 EIM80364.1 - 4.8e-20 72.1 0.0 6.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EIM80364.1 - 1.3e-07 31.7 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 ABC_membrane PF00664.23 EIM80365.1 - 5.3e-49 167.3 25.2 1.4e-31 110.2 2.8 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM80365.1 - 1e-40 139.5 0.0 1.1e-24 87.5 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM80365.1 - 2.7e-06 27.0 1.1 0.71 9.3 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIM80365.1 - 1.9e-05 24.4 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIM80365.1 - 0.0001 22.7 0.0 0.88 9.9 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 EIM80365.1 - 0.00067 20.2 4.5 0.0039 17.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EIM80365.1 - 0.00068 19.3 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIM80365.1 - 0.00082 19.4 0.4 0.78 9.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 EIM80365.1 - 0.00085 19.5 0.2 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EIM80365.1 - 0.0014 18.6 0.1 0.57 10.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EIM80365.1 - 0.0014 18.5 1.9 0.42 10.4 0.3 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EIM80365.1 - 0.0052 16.3 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EIM80365.1 - 0.015 14.7 0.1 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 EIM80365.1 - 0.025 13.4 0.0 0.27 10.0 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein T2SSE PF00437.20 EIM80365.1 - 0.03 13.4 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 EIM80365.1 - 0.063 13.0 0.0 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 EIM80365.1 - 0.065 12.7 0.1 6 6.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.17 EIM80365.1 - 0.082 12.6 0.6 26 4.5 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Roc PF08477.13 EIM80365.1 - 0.11 12.8 0.2 20 5.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EIM80365.1 - 0.11 12.8 0.0 7.8 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EIM80365.1 - 0.11 12.5 1.4 9.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 EIM80365.1 - 0.16 12.4 0.3 2.1 8.8 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM80365.1 - 0.21 11.6 1.3 27 4.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EIM80365.1 - 0.24 11.2 1.2 4.4 7.0 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UCH PF00443.29 EIM80366.1 - 8.8e-63 212.2 0.0 1.4e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM80366.1 - 2.8e-19 69.9 0.2 1.7e-16 60.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EIM80366.1 - 0.00079 19.9 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 EIM80366.1 - 0.01 16.0 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain zf-MIZ PF02891.20 EIM80366.1 - 0.022 14.5 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger ABC_membrane PF00664.23 EIM80367.1 - 5.6e-48 164.0 30.5 7.9e-30 104.4 5.0 4.0 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM80367.1 - 2.4e-44 151.2 0.0 5.3e-28 98.2 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM80367.1 - 3.3e-13 49.6 2.5 0.00015 21.3 0.3 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIM80367.1 - 3.4e-06 27.7 0.9 0.0019 18.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIM80367.1 - 3.9e-06 26.9 1.8 0.031 14.1 0.1 4.0 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EIM80367.1 - 2.2e-05 24.9 0.0 0.4 11.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 EIM80367.1 - 6e-05 22.7 0.1 0.61 9.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EIM80367.1 - 0.00018 21.2 0.1 0.44 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIM80367.1 - 0.00019 21.5 2.5 0.23 11.6 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EIM80367.1 - 0.00045 20.0 1.6 1 9.1 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein T2SSE PF00437.20 EIM80367.1 - 0.00094 18.3 0.0 0.41 9.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EIM80367.1 - 0.00098 19.1 0.2 0.8 9.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EIM80367.1 - 0.0016 18.9 0.8 0.23 11.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 EIM80367.1 - 0.0019 17.1 0.0 0.038 12.8 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_22 PF13401.6 EIM80367.1 - 0.0025 18.1 0.2 2.8 8.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EIM80367.1 - 0.0037 16.8 0.0 0.73 9.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 EIM80367.1 - 0.0071 16.5 0.3 0.1 12.7 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 EIM80367.1 - 0.015 15.0 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 EIM80367.1 - 0.023 14.7 1.6 4.4 7.3 0.1 3.7 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EIM80367.1 - 0.044 13.7 0.1 0.9 9.4 0.0 2.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 EIM80367.1 - 0.06 12.7 0.3 8.2 5.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 EIM80367.1 - 0.092 12.2 0.1 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.6 EIM80367.1 - 0.12 12.9 0.0 28 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIM80367.1 - 0.14 12.5 0.1 13 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC2_membrane_2 PF12679.7 EIM80367.1 - 0.14 11.4 6.5 5.6 6.1 0.1 3.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Dynamin_N PF00350.23 EIM80367.1 - 0.16 12.0 1.0 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.9 EIM80367.1 - 0.27 11.0 2.4 5.3 6.8 0.1 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF1282 PF06930.12 EIM80367.1 - 2.8 7.7 8.8 0.9 9.3 3.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1282) TMEM132D_C PF15706.5 EIM80367.1 - 4.9 7.0 7.6 18 5.2 0.2 3.3 3 0 0 3 3 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Rxt3 PF08642.10 EIM80368.1 - 0.024 15.4 0.0 0.024 15.4 0.0 4.8 6 1 0 6 6 6 0 Histone deacetylation protein Rxt3 Cytomega_UL20A PF05984.12 EIM80368.1 - 10 6.5 10.0 34 4.8 0.2 3.1 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Ran_BP1 PF00638.18 EIM80369.1 - 2.7e-14 53.5 0.0 4.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain HATPase_c PF02518.26 EIM80370.1 - 3.9e-22 78.9 0.1 7.2e-21 74.8 0.1 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM80370.1 - 6.9e-18 64.9 0.0 3.1e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EIM80370.1 - 2e-07 30.9 0.0 4.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EIM80370.1 - 0.043 13.6 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.14 EIM80370.1 - 0.94 7.7 5.9 1.7 6.9 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-HC5HC2H_2 PF13832.6 EIM80371.1 - 1.5e-18 67.0 6.6 1.5e-18 67.0 6.6 5.0 4 1 1 5 5 5 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EIM80371.1 - 3.1e-14 53.0 7.1 3.1e-14 53.0 7.1 4.9 5 2 1 6 6 6 2 PHD-like zinc-binding domain BAH PF01426.18 EIM80371.1 - 1e-12 48.0 0.0 2.5e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 EIM80371.1 - 6.7e-09 35.5 41.8 4.4e-07 29.7 11.8 6.2 7 2 0 7 7 7 3 PHD-finger GATA PF00320.27 EIM80371.1 - 1.3e-05 24.7 14.1 0.00087 18.9 5.6 3.2 2 0 0 2 2 2 2 GATA zinc finger PHD_2 PF13831.6 EIM80371.1 - 5.6e-05 22.6 4.2 5.6e-05 22.6 4.2 6.0 6 0 0 6 6 6 2 PHD-finger ELM2 PF01448.24 EIM80371.1 - 0.0027 18.4 0.0 0.0078 16.9 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain AT_hook PF02178.19 EIM80371.1 - 0.025 14.4 2.4 0.094 12.6 2.4 2.1 1 0 0 1 1 1 0 AT hook motif Myb_DNA-binding PF00249.31 EIM80371.1 - 0.038 14.2 0.2 0.084 13.1 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain GST_C PF00043.25 EIM80371.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DHFR_1 PF00186.19 EIM80372.1 - 6.1e-24 84.5 0.0 2.3e-23 82.7 0.0 2.0 1 1 1 2 2 2 1 Dihydrofolate reductase ABC_membrane PF00664.23 EIM80373.1 - 7.8e-50 170.1 22.6 1.1e-31 110.5 6.3 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM80373.1 - 1.2e-45 155.4 0.0 1.3e-26 93.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM80373.1 - 3.8e-13 49.4 5.2 6.2e-05 22.5 0.5 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIM80373.1 - 6.3e-07 29.2 0.1 0.15 11.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EIM80373.1 - 1.8e-06 28.6 0.2 0.00071 20.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIM80373.1 - 2.7e-06 27.9 0.2 0.06 13.7 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 EIM80373.1 - 3e-05 24.0 0.1 0.03 14.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM80373.1 - 8.7e-05 22.2 0.5 0.6 9.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIM80373.1 - 0.00025 21.1 0.7 0.46 10.6 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA PF00004.29 EIM80373.1 - 0.00061 20.2 0.6 0.22 11.9 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIM80373.1 - 0.00078 19.0 0.1 0.33 10.4 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_22 PF13401.6 EIM80373.1 - 0.0013 19.0 0.4 1.2 9.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EIM80373.1 - 0.0017 18.3 0.1 0.4 10.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 EIM80373.1 - 0.0028 17.7 0.4 2.9 7.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIM80373.1 - 0.0039 16.9 0.1 5.3 6.7 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF87 PF01935.17 EIM80373.1 - 0.0042 17.2 0.2 0.094 12.8 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 EIM80373.1 - 0.011 14.9 0.0 0.44 9.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 EIM80373.1 - 0.015 15.1 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 EIM80373.1 - 0.031 13.1 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Roc PF08477.13 EIM80373.1 - 0.036 14.3 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EIM80373.1 - 0.036 14.4 0.1 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 EIM80373.1 - 0.043 13.7 0.1 0.41 10.5 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EIM80373.1 - 0.059 13.1 0.5 15 5.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EIM80373.1 - 0.079 12.7 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 EIM80373.1 - 0.091 12.2 0.2 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 EIM80373.1 - 0.11 11.9 0.3 15 4.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EIM80373.1 - 0.13 12.4 0.8 7.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.22 EIM80373.1 - 0.13 11.4 0.1 8.7 5.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 EIM80373.1 - 0.14 12.0 0.4 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.15 EIM80373.1 - 0.18 11.8 0.0 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EIM80373.1 - 0.19 12.3 0.0 31 5.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain APH PF01636.23 EIM80374.1 - 0.0034 17.3 0.1 0.0066 16.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM80374.1 - 0.049 13.0 0.1 0.086 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 EIM80374.1 - 0.11 12.1 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 RIO1 family ADIP PF11559.8 EIM80375.1 - 4.8e-19 68.9 6.8 4.8e-19 68.9 6.8 3.4 2 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding AIP3 PF03915.13 EIM80375.1 - 0.088 11.9 10.3 0.024 13.8 3.6 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 Fez1 PF06818.15 EIM80375.1 - 0.73 10.3 16.7 0.16 12.4 3.6 2.8 2 0 0 2 2 2 0 Fez1 APG6_N PF17675.1 EIM80375.1 - 6.7 7.3 31.1 5.3 7.6 12.6 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region ABC_membrane PF00664.23 EIM80376.1 - 1.4e-50 172.4 28.3 9.6e-33 114.0 4.3 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM80376.1 - 1.1e-41 142.5 0.0 1.1e-25 90.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM80376.1 - 8.6e-11 41.7 5.9 0.0005 19.6 0.7 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIM80376.1 - 1.6e-05 24.6 0.0 0.27 10.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EIM80376.1 - 5.3e-05 23.7 0.5 0.38 11.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 EIM80376.1 - 0.00039 20.3 2.0 0.37 10.6 0.2 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM80376.1 - 0.0006 19.5 0.1 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EIM80376.1 - 0.00088 19.8 4.9 0.0039 17.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 EIM80376.1 - 0.00092 19.3 0.4 0.85 9.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 EIM80376.1 - 0.0011 19.1 0.6 0.14 12.3 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EIM80376.1 - 0.0013 18.7 0.1 0.57 10.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 EIM80376.1 - 0.0056 16.2 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 EIM80376.1 - 0.024 15.0 0.5 2.6 8.5 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EIM80376.1 - 0.027 13.6 0.0 2.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EIM80376.1 - 0.028 13.8 0.1 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 EIM80376.1 - 0.029 13.2 0.0 0.32 9.7 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 EIM80376.1 - 0.045 13.5 0.6 26 4.5 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.6 EIM80376.1 - 0.047 14.0 0.7 11 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EIM80376.1 - 0.087 12.5 0.1 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EIM80376.1 - 0.091 13.0 0.1 18 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EIM80376.1 - 0.099 12.7 2.7 2.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 EIM80376.1 - 0.11 11.9 0.5 9.2 5.6 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 EIM80376.1 - 0.11 12.4 1.2 27 4.7 0.1 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EIM80376.1 - 0.67 9.7 3.1 4.5 7.0 0.1 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.16 EIM80377.1 - 1.8e-42 145.5 33.1 1.8e-42 145.5 33.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 EIM80377.1 - 0.0018 18.4 2.7 1.5 9.0 0.0 3.5 3 0 0 3 3 3 2 Poxvirus virion envelope protein A14 FAM91_N PF14647.6 EIM80377.1 - 0.15 11.4 0.1 0.21 10.9 0.1 1.1 1 0 0 1 1 1 0 FAM91 N-terminus p450 PF00067.22 EIM80379.1 - 1.4e-53 182.3 0.0 1.9e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L5 PF00281.19 EIM80380.1 - 1.1e-20 73.7 0.1 2.5e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 EIM80380.1 - 1.5e-20 73.1 0.0 2.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Syndecan PF01034.20 EIM80382.1 - 0.11 12.4 0.3 0.24 11.3 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 EIM80383.1 - 1.2e-07 31.4 0.1 0.0002 20.8 0.0 2.6 2 1 0 3 3 3 2 Protein kinase domain Phe_tRNA-synt_N PF02912.18 EIM80383.1 - 0.029 14.3 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Pkinase_Tyr PF07714.17 EIM80383.1 - 0.046 13.0 0.0 0.09 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM80383.1 - 0.079 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase MFS_1 PF07690.16 EIM80384.1 - 2.5e-33 115.5 33.2 3.4e-27 95.3 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydantoinase_B PF02538.14 EIM80385.1 - 1.5e-179 597.7 0.4 2e-179 597.3 0.4 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EIM80385.1 - 9.6e-98 327.0 0.0 3.5e-97 325.2 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EIM80385.1 - 8.3e-56 188.5 2.5 5.1e-54 182.7 0.0 3.4 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase N-terminal region Glyco_hydro_79C PF16862.5 EIM80386.1 - 1.6e-18 67.5 0.1 1.6e-18 67.5 0.1 2.9 3 1 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Alpha_GJ PF03229.13 EIM80386.1 - 0.003 18.1 1.5 0.003 18.1 1.5 3.0 2 0 0 2 2 2 1 Alphavirus glycoprotein J adh_short PF00106.25 EIM80387.1 - 4.2e-16 59.0 0.0 2.5e-11 43.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM80387.1 - 7e-14 51.9 0.0 5.3e-10 39.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM80387.1 - 0.0069 16.3 0.0 0.0085 16.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF4046 PF13255.6 EIM80387.1 - 0.17 12.5 0.1 0.31 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) MBOAT PF03062.19 EIM80388.1 - 2e-32 112.9 16.3 2e-32 112.9 16.3 2.4 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EIM80388.1 - 4.8e-05 23.5 5.3 0.00016 21.9 5.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GIIM PF08388.11 EIM80388.1 - 0.096 12.8 0.6 0.23 11.6 0.6 1.6 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Fumarate_red_D PF02313.17 EIM80388.1 - 7.5 6.7 11.7 0.06 13.4 1.6 2.5 3 0 0 3 3 3 0 Fumarate reductase subunit D Clr2_transil PF16761.5 EIM80389.1 - 6.6e-24 84.5 0.8 1.4e-23 83.5 0.8 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EIM80389.1 - 2.8e-10 41.2 0.0 4e-09 37.4 0.0 2.7 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 WD40 PF00400.32 EIM80390.1 - 7e-11 42.5 5.0 0.79 10.7 0.1 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM80390.1 - 0.0032 17.8 0.3 11 6.4 0.0 4.5 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Carm_PH PF17888.1 EIM80390.1 - 0.081 13.3 0.1 15 6.0 0.0 3.2 2 1 1 3 3 3 0 Carmil pleckstrin homology domain COX6C PF02937.15 EIM80391.1 - 0.0062 16.6 0.0 0.0068 16.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc COesterase PF00135.28 EIM80392.1 - 5.3e-81 273.0 0.0 7.8e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM80392.1 - 5.4e-08 32.9 0.3 0.00049 20.0 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold MFP2b PF12150.8 EIM80392.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytosolic motility protein Rad9 PF04139.13 EIM80393.1 - 1.4e-48 165.6 0.0 3.8e-48 164.1 0.0 1.7 2 0 0 2 2 2 1 Rad9 TFIIA PF03153.13 EIM80393.1 - 0.046 13.7 6.2 0.073 13.1 6.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EIM80393.1 - 0.59 9.3 9.6 0.77 8.9 9.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PAT1 PF09770.9 EIM80393.1 - 5.6 5.1 10.0 7.3 4.7 10.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Coatomer_E PF04733.14 EIM80394.1 - 2e-44 152.1 0.0 2.3e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 EIM80394.1 - 0.00039 20.3 0.0 1.7 8.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat SPOR PF05036.13 EIM80394.1 - 0.023 15.0 0.2 3.4 8.1 0.1 2.9 2 1 0 2 2 2 0 Sporulation related domain TPR_19 PF14559.6 EIM80394.1 - 0.028 14.9 3.9 2.3 8.8 0.2 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EIM80394.1 - 0.079 13.1 0.0 0.079 13.1 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3046 PF11248.8 EIM80394.1 - 0.096 13.1 0.2 0.56 10.6 0.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3046) TPR_14 PF13428.6 EIM80394.1 - 1.8 9.6 12.5 7.6 7.6 0.4 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.8 EIM80396.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF4667 PF15700.5 EIM80396.1 - 1 9.4 15.2 0.064 13.3 9.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Thymidylate_kin PF02223.17 EIM80398.1 - 4.8e-43 147.0 0.0 6.5e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EIM80398.1 - 0.0097 15.4 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 EIM80398.1 - 0.014 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 EIM80398.1 - 0.066 13.1 0.0 0.49 10.2 0.0 2.0 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_33 PF13671.6 EIM80398.1 - 0.077 13.2 0.0 0.32 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EIM80398.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RIC3 PF15361.6 EIM80399.1 - 0.025 15.0 0.0 0.025 15.0 0.0 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Cas_CXXC_CXXC PF09706.10 EIM80399.1 - 0.75 10.1 4.4 4.5 7.6 4.4 1.9 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Glyco_hydro_47 PF01532.20 EIM80400.1 - 1.2e-136 456.3 0.0 1.3e-136 456.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MBOAT_2 PF13813.6 EIM80401.1 - 3.3e-12 46.5 1.6 6.6e-12 45.5 1.6 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_47 PF01532.20 EIM80402.1 - 9.2e-137 456.7 0.0 1.1e-136 456.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.13 EIM80403.1 - 3.3e-26 91.7 0.0 6e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family LmjF365940-deam PF14421.6 EIM80403.1 - 0.014 15.1 2.1 0.021 14.4 2.1 1.5 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Bd3614-deam PF14439.6 EIM80403.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase Succ_DH_flav_C PF02910.20 EIM80403.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Zip PF02535.22 EIM80404.1 - 4.3e-61 207.0 10.3 4.9e-61 206.8 10.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Clr2_transil PF16761.5 EIM80405.1 - 4.9e-23 81.7 1.4 8.7e-23 80.9 1.4 1.4 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EIM80405.1 - 2e-11 44.9 0.1 1.8e-09 38.5 0.1 3.0 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 WD40 PF00400.32 EIM80406.1 - 1.4e-07 32.1 1.9 0.02 15.7 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat CPSF_A PF03178.15 EIM80406.1 - 0.2 10.9 0.0 0.87 8.8 0.0 1.8 1 1 1 2 2 2 0 CPSF A subunit region FGGY_N PF00370.21 EIM80407.1 - 1.8e-61 207.9 0.0 1.6e-59 201.5 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EIM80407.1 - 5.9e-59 199.1 1.5 1.1e-58 198.3 1.5 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Lipoprotein_9 PF03180.14 EIM80407.1 - 0.22 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein AAA_16 PF13191.6 EIM80408.1 - 0.0043 17.4 0.0 0.0076 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM80408.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EIM80408.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 KaiC Hpr_kinase_C PF07475.12 EIM80408.1 - 0.015 14.8 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.14 EIM80408.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 EIM80408.1 - 0.022 13.7 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain GvpD PF07088.11 EIM80408.1 - 0.06 12.0 0.0 0.11 11.1 0.0 1.4 2 0 0 2 2 2 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 EIM80408.1 - 0.064 13.0 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain RHSP PF07999.11 EIM80408.1 - 0.069 12.0 0.1 0.09 11.6 0.1 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein NACHT PF05729.12 EIM80408.1 - 0.11 12.4 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 EIM80408.1 - 0.12 12.1 0.1 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EIM80408.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EIM80408.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 NTPase TNT PF14021.6 EIM80409.1 - 4.6e-31 107.2 0.1 7.5e-31 106.5 0.1 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin HSP20 PF00011.21 EIM80410.1 - 3e-14 53.0 0.0 5.5e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EIM80410.1 - 4.9e-12 45.2 0.1 4.6e-11 42.1 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 EIM80410.1 - 9.9e-05 22.5 0.4 0.0042 17.2 0.0 2.1 2 0 0 2 2 2 1 GvpH Pneumo_att_G PF05539.11 EIM80410.1 - 0.12 12.0 2.9 0.16 11.5 2.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RED_N PF07808.13 EIM80411.1 - 9.7e-17 61.3 5.4 3.7e-16 59.4 5.4 2.0 1 0 0 1 1 1 1 RED-like protein N-terminal region KAR9 PF08580.10 EIM80412.1 - 1.3e-17 63.7 54.8 1.3e-17 63.7 54.8 4.3 2 2 1 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.17 EIM80412.1 - 7.5e-06 25.9 0.2 1.8e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Cauli_AT PF03233.13 EIM80412.1 - 1.3 8.9 6.1 5.3 7.0 0.1 3.0 3 0 0 3 3 3 0 Aphid transmission protein Pkinase PF00069.25 EIM80413.1 - 1.8e-69 234.0 0.0 2.9e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM80413.1 - 3.1e-47 161.0 0.0 5.1e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EIM80413.1 - 1.3e-21 76.7 0.0 3.8e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EIM80413.1 - 1.7e-06 27.1 0.5 3e-06 26.3 0.5 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIM80413.1 - 0.00022 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM80413.1 - 0.05 13.0 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sde2_N_Ubi PF13019.6 EIM80413.1 - 0.061 13.1 0.0 0.061 13.1 0.0 2.5 3 0 0 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain DSHCT PF08148.12 EIM80413.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 EIM80413.1 - 0.48 10.3 4.4 0.54 10.1 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RR_TM4-6 PF06459.12 EIM80413.1 - 1.9 8.2 6.9 4.5 7.0 6.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Thaumatin PF00314.17 EIM80416.1 - 2.3e-18 66.7 2.6 2.7e-18 66.4 2.6 1.1 1 0 0 1 1 1 1 Thaumatin family PI3_PI4_kinase PF00454.27 EIM80417.1 - 7e-52 176.7 0.6 2.3e-51 175.0 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EIM80417.1 - 8.7e-38 129.8 0.1 8.7e-38 129.8 0.1 3.3 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EIM80417.1 - 4.7e-11 42.3 0.0 1.3e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 FATC domain TipAS PF07739.13 EIM80417.1 - 0.026 15.1 3.9 0.031 14.8 1.1 2.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain PTR2 PF00854.21 EIM80418.1 - 2.7e-59 201.0 11.6 3.8e-59 200.5 11.6 1.1 1 0 0 1 1 1 1 POT family Anoctamin PF04547.12 EIM80419.1 - 6.7e-106 354.8 1.6 8.4e-106 354.5 1.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3915 PF13054.6 EIM80420.1 - 0.12 12.3 16.5 1.5 8.8 11.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) MFS_1 PF07690.16 EIM80424.1 - 4.1e-17 62.2 27.7 2.6e-12 46.4 14.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ANTH PF07651.16 EIM80425.1 - 1.9e-51 174.7 0.1 2.7e-51 174.2 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EIM80425.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 ENTH domain Glyco_hydro_47 PF01532.20 EIM80426.1 - 5.9e-128 427.6 0.0 7.1e-128 427.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HSP20 PF00011.21 EIM80427.1 - 3.9e-13 49.4 0.0 3.6e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EIM80427.1 - 1.1e-10 40.9 0.4 1.2e-09 37.6 0.4 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 EIM80427.1 - 0.00087 19.4 0.4 0.003 17.6 0.0 2.0 2 1 0 2 2 2 1 GvpH AAA PF00004.29 EIM80428.1 - 2.9e-42 144.2 0.1 8.1e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM80428.1 - 6.8e-12 45.0 0.2 1.7e-11 43.8 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EIM80428.1 - 6.5e-11 42.0 0.4 2.4e-10 40.2 0.0 2.2 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EIM80428.1 - 3.3e-07 30.8 0.0 0.00018 21.9 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EIM80428.1 - 3.4e-07 30.3 0.1 4.7e-06 26.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIM80428.1 - 4.5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EIM80428.1 - 9.8e-06 25.8 0.0 3.3e-05 24.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EIM80428.1 - 0.0004 20.7 0.1 0.019 15.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EIM80428.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 EIM80428.1 - 0.0025 17.4 0.1 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 EIM80428.1 - 0.0031 18.0 0.1 0.012 16.2 0.0 2.1 2 1 1 3 3 1 1 AAA domain Mg_chelatase PF01078.21 EIM80428.1 - 0.0043 16.5 0.0 0.0095 15.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EIM80428.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 EIM80428.1 - 0.0047 16.9 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EIM80428.1 - 0.0054 17.1 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EIM80428.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 EIM80428.1 - 0.008 15.9 0.2 0.041 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EIM80428.1 - 0.0092 15.7 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 EIM80428.1 - 0.0093 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain PhoH PF02562.16 EIM80428.1 - 0.011 15.2 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EIM80428.1 - 0.014 15.5 0.0 0.085 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EIM80428.1 - 0.017 15.3 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 EIM80428.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EIM80428.1 - 0.019 15.2 0.1 0.056 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EIM80428.1 - 0.023 14.3 0.6 0.066 12.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EIM80428.1 - 0.029 13.7 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 EIM80428.1 - 0.035 13.2 0.3 0.073 12.1 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EIM80428.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EIM80428.1 - 0.055 12.8 0.8 0.18 11.2 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 EIM80428.1 - 0.056 13.2 1.6 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EIM80428.1 - 0.082 13.4 0.3 21 5.5 0.6 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EIM80428.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 EIM80428.1 - 0.095 13.0 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 EIM80428.1 - 0.73 10.2 7.1 0.083 13.3 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GCFC PF07842.12 EIM80429.1 - 1.7e-67 228.0 0.9 1.3e-64 218.5 0.2 2.5 2 1 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 EIM80429.1 - 4.9e-14 52.6 11.7 4.9e-14 52.6 11.7 3.2 4 0 0 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.23 EIM80429.1 - 2.3e-13 49.8 1.6 7.7e-13 48.1 1.6 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EIM80429.1 - 6.3e-08 32.6 0.5 6.3e-08 32.6 0.5 2.9 3 0 0 3 3 3 1 G-patch domain T2SSM PF04612.12 EIM80429.1 - 0.97 9.5 5.6 0.48 10.5 0.7 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Pro-kuma_activ PF09286.11 EIM80430.1 - 4.3e-37 127.6 0.1 9e-37 126.5 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM80430.1 - 5.5e-05 22.6 1.2 0.00013 21.3 1.2 1.5 1 1 0 1 1 1 1 Subtilase family FGGY_N PF00370.21 EIM80433.1 - 2.1e-28 99.5 0.0 5.1e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EIM80433.1 - 1.3e-16 60.9 0.0 2.9e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PIF1 PF05970.14 EIM80434.1 - 5.4e-62 210.1 3.0 1e-51 176.2 1.5 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EIM80434.1 - 5.9e-22 78.3 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM80434.1 - 2e-12 47.7 0.0 3.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EIM80434.1 - 1.6e-07 29.7 0.2 4.8e-06 24.8 0.0 2.3 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 EIM80434.1 - 8.5e-05 22.8 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EIM80434.1 - 0.00011 21.9 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EIM80434.1 - 0.00079 19.2 3.0 0.79 9.4 0.2 3.2 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EIM80434.1 - 0.00088 18.8 0.1 0.0019 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EIM80434.1 - 0.0041 17.5 0.2 0.0087 16.5 0.2 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM80434.1 - 0.005 17.2 0.1 0.01 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 EIM80434.1 - 0.0059 16.1 0.1 0.018 14.5 0.1 1.8 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.14 EIM80434.1 - 0.025 14.6 0.2 0.11 12.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EIM80434.1 - 0.039 13.9 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF5605 PF18310.1 EIM80434.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) RNA_helicase PF00910.22 EIM80434.1 - 0.062 13.7 0.1 0.18 12.2 0.1 1.9 1 1 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EIM80434.1 - 0.075 12.3 0.1 0.16 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EIM80434.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EIM80434.1 - 0.14 12.1 0.8 0.61 10.0 0.8 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SH3_13 PF18335.1 EIM80434.1 - 0.14 12.0 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Muraidase PF11860.8 EIM80434.1 - 0.19 12.0 0.4 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramidase Helicase_RecD PF05127.14 EIM80434.1 - 0.2 11.5 0.8 0.65 9.8 0.8 1.8 1 1 0 1 1 1 0 Helicase GREB1 PF15782.5 EIM80434.1 - 2.8 4.9 13.5 3.8 4.5 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 EIM80434.1 - 3.4 6.8 20.0 5 6.2 20.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EIM80434.1 - 6.6 6.5 16.5 11 5.8 16.5 1.3 1 0 0 1 1 1 0 SPX domain VPS9 PF02204.18 EIM80435.1 - 4.9e-17 62.0 0.0 3.4e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EIM80435.1 - 0.036 14.4 0.1 0.16 12.3 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Cnd2 PF05786.14 EIM80435.1 - 0.47 9.1 3.2 0.82 8.2 3.2 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 CENP-B_dimeris PF09026.10 EIM80435.1 - 1.2 9.6 12.0 0.081 13.3 5.8 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EIM80435.1 - 6.8 4.7 7.4 12 3.8 7.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi YAF2_RYBP PF17219.3 EIM80438.1 - 0.18 11.4 0.4 0.41 10.3 0.4 1.6 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif DUF3810 PF12725.7 EIM80439.1 - 0.26 10.6 0.1 0.33 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ribosomal_L37e PF01907.19 EIM80441.1 - 6.8e-21 74.2 12.1 1e-20 73.6 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EIM80441.1 - 0.014 15.4 2.0 0.018 15.0 2.0 1.2 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 EIM80441.1 - 0.039 14.0 1.4 0.05 13.6 1.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_2 PF13923.6 EIM80441.1 - 0.17 11.7 4.6 0.31 10.9 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zn-ribbon_14 PF16503.5 EIM80441.1 - 0.5 9.9 4.8 0.99 9.0 0.2 2.1 2 0 0 2 2 2 0 Zinc-ribbon DUF2688 PF10892.8 EIM80441.1 - 3.1 7.4 6.1 11 5.6 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) UQ_con PF00179.26 EIM80442.1 - 1.6e-17 63.5 0.0 2.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CRT10 PF08728.10 EIM80443.1 - 0.3 9.2 3.2 0.31 9.2 3.2 1.0 1 0 0 1 1 1 0 CRT10 DUF5082 PF16888.5 EIM80443.1 - 0.41 10.9 4.8 0.59 10.4 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Pro_isomerase PF00160.21 EIM80444.1 - 3.7e-41 141.0 0.0 4.9e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD INTAP PF16617.5 EIM80445.1 - 0.082 13.3 6.9 0.24 11.8 0.1 2.9 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Ribosomal_S4e PF00900.20 EIM80448.1 - 5.6e-36 122.3 0.6 1.7e-35 120.8 0.3 1.9 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EIM80448.1 - 1.6e-26 91.7 0.2 3.6e-26 90.6 0.2 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EIM80448.1 - 4.3e-21 74.7 5.8 8e-21 73.9 5.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EIM80448.1 - 4.7e-07 29.4 0.1 1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EIM80448.1 - 3.8e-06 26.7 3.5 1.2e-05 25.1 3.5 1.9 1 0 0 1 1 1 1 KOW motif hSac2 PF12456.8 EIM80448.1 - 0.096 12.4 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Inositol phosphatase MFS_1 PF07690.16 EIM80449.1 - 1.3e-43 149.3 41.9 2.4e-33 115.5 25.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SH3_9 PF14604.6 EIM80450.1 - 7e-08 32.2 0.1 1.3e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIM80450.1 - 7.8e-07 28.6 0.0 1.7e-06 27.6 0.0 1.6 1 1 1 2 2 2 1 SH3 domain SH3_2 PF07653.17 EIM80450.1 - 0.00066 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 EIM80450.1 - 0.087 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain DUF3952 PF13130.6 EIM80450.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) XRCC4 PF06632.12 EIM80452.1 - 0.37 9.6 4.0 0.64 8.8 4.0 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spherulin4 PF12138.8 EIM80453.1 - 2.5e-63 213.9 2.5 2.9e-63 213.7 2.5 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 NMT1 PF09084.11 EIM80454.1 - 2.2e-08 34.3 0.0 3.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EIM80454.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family Cnd2 PF05786.14 EIM80455.1 - 1.5e-171 572.9 15.9 2.3e-170 568.9 15.9 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EIM80455.1 - 0.014 15.6 1.1 0.081 13.1 0.0 2.7 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Shikimate_dh_N PF08501.11 EIM80457.1 - 7e-20 71.1 0.0 2.4e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EIM80457.1 - 4.8e-10 39.0 0.2 9e-10 38.1 0.2 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Se-cys_synth_N PF12390.8 EIM80457.1 - 0.13 12.5 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Sugar_tr PF00083.24 EIM80458.1 - 1.4e-112 376.9 30.4 1.7e-112 376.6 30.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM80458.1 - 4.3e-27 95.0 34.5 4.1e-16 58.8 8.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily YqfD PF06898.11 EIM80458.1 - 0.29 9.9 0.8 0.5 9.1 0.8 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Cu PF17563.2 EIM80459.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupiennin Atx10homo_assoc PF09759.9 EIM80460.1 - 2.9e-27 94.6 0.0 1.8e-24 85.6 0.0 3.2 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain TRAUB PF08164.12 EIM80462.1 - 1.3e-29 102.5 0.0 1.3e-29 102.5 0.0 2.6 3 2 1 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EIM80462.1 - 6.7e-25 88.4 0.0 6.7e-25 88.4 0.0 2.6 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor V-ATPase_G_2 PF16999.5 EIM80462.1 - 0.0077 16.6 2.0 0.0077 16.6 2.0 2.7 3 0 0 3 3 3 1 Vacuolar (H+)-ATPase G subunit CDC45 PF02724.14 EIM80462.1 - 0.08 11.2 16.4 0.19 10.0 16.4 1.5 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EIM80462.1 - 3.2 7.0 18.1 8 5.7 18.1 1.6 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.7 EIM80462.1 - 8.5 4.4 6.6 13 3.7 6.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-X PF09415.10 EIM80463.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.1 1 0 0 1 1 1 0 CENP-S associating Centromere protein X LSM PF01423.22 EIM80464.1 - 2.1e-17 62.6 0.3 2.9e-17 62.1 0.3 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EIM80464.1 - 0.0073 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Hfq protein Propep_M14 PF02244.16 EIM80464.1 - 0.1 13.0 0.8 0.13 12.6 0.8 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Pescadillo_N PF06732.11 EIM80465.1 - 9.4e-121 402.5 0.0 9.4e-121 402.5 0.0 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EIM80465.1 - 1.4e-09 38.2 0.0 3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIM80465.1 - 0.00065 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EIM80465.1 - 0.0015 18.7 0.4 0.0055 17.0 0.0 2.2 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain MOZART1 PF12554.8 EIM80466.1 - 6.5e-25 86.7 0.6 8.4e-25 86.3 0.6 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Sporozoite_P67 PF05642.11 EIM80467.1 - 5 5.1 21.3 0.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 EIM80467.1 - 7.7 4.5 27.3 13 3.8 27.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi Dus PF01207.17 EIM80469.1 - 7.1e-69 232.3 0.0 9.6e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 EIM80469.1 - 6.8e-05 22.8 0.0 0.012 15.5 0.0 2.4 1 1 1 2 2 2 2 SOR/SNZ family ThiG PF05690.14 EIM80469.1 - 0.00034 20.0 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 EIM80469.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase p450 PF00067.22 EIM80470.1 - 4.7e-56 190.5 0.0 6.8e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M24 PF00557.24 EIM80470.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 zf-RING_UBOX PF13445.6 EIM80472.1 - 1.4e-11 44.2 7.6 1.4e-11 44.2 7.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM80472.1 - 3.9e-10 39.7 13.5 6.6e-10 39.0 13.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EIM80472.1 - 1.1e-09 38.0 12.6 1.8e-09 37.3 12.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM80472.1 - 3.7e-09 36.3 12.8 3.1e-08 33.3 12.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM80472.1 - 5.1e-09 36.3 12.2 8.5e-09 35.6 12.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EIM80472.1 - 7.7e-09 35.3 10.5 1.7e-08 34.1 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM80472.1 - 6e-06 26.1 11.5 1.3e-05 25.1 11.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EIM80472.1 - 0.00027 20.6 4.3 0.00073 19.2 4.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 EIM80472.1 - 0.0017 18.2 16.0 0.0074 16.1 15.1 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Nup54 PF13874.6 EIM80472.1 - 0.033 14.3 0.3 0.048 13.8 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-RING_6 PF14835.6 EIM80472.1 - 0.13 12.2 7.8 0.29 11.0 7.8 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 EIM80472.1 - 0.39 10.9 9.8 1.5 9.0 9.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.7 EIM80472.1 - 0.4 11.0 11.9 1.2 9.5 11.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EIM80472.1 - 0.49 10.2 11.2 6.4 6.7 11.2 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EIM80472.1 - 0.63 9.9 8.8 1.1 9.1 8.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit UPF0547 PF10571.9 EIM80472.1 - 2.4 8.3 8.9 2.9 8.1 0.2 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2_4 PF13894.6 EIM80472.1 - 9.2 7.4 8.5 4.7 8.3 0.2 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger Aminotran_5 PF00266.19 EIM80473.1 - 7.8e-27 94.2 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EIM80473.1 - 5.7e-06 25.1 1.4 7.4e-06 24.7 0.4 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Epimerase PF01370.21 EIM80473.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WD40 PF00400.32 EIM80474.1 - 4.1e-09 36.9 14.4 0.081 13.8 0.4 7.9 8 1 0 8 8 8 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EIM80474.1 - 0.017 15.6 0.2 1.4 9.5 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain HAND PF09110.11 EIM80474.1 - 0.45 11.3 10.2 0.99 10.2 10.2 1.5 1 0 0 1 1 1 0 HAND tRNA_int_endo PF01974.17 EIM80475.1 - 9.4e-16 57.7 0.4 2.7e-15 56.2 0.4 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EIM80475.1 - 0.0004 20.0 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Zn_clus PF00172.18 EIM80476.1 - 1.3e-06 28.4 8.0 1.3e-06 28.4 8.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.9 EIM80476.1 - 0.074 13.2 0.5 0.22 11.7 0.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Mg_trans_NIPA PF05653.14 EIM80477.1 - 1.1e-86 290.6 25.7 1.6e-86 290.1 25.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EIM80477.1 - 1e-06 28.9 5.4 1e-06 28.9 5.4 3.7 3 1 0 3 3 3 1 EamA-like transporter family PAPS_reduct PF01507.19 EIM80479.1 - 3.1e-39 134.8 0.0 4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Abhydrolase_1 PF00561.20 EIM80480.1 - 4e-11 43.0 0.0 1.1e-10 41.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM80480.1 - 0.00059 20.5 0.0 0.00074 20.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM80480.1 - 0.15 11.3 0.0 0.34 10.1 0.0 1.8 2 1 0 2 2 2 0 Serine aminopeptidase, S33 LRR_6 PF13516.6 EIM80482.1 - 4.3e-11 41.9 0.5 0.00022 21.0 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 EIM80482.1 - 3.9e-07 30.3 5.6 0.015 15.7 0.7 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIM80482.1 - 0.00073 19.8 4.3 2.3 9.1 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.6 EIM80482.1 - 0.16 11.8 5.4 14 5.5 2.4 3.8 1 1 1 2 2 2 0 Leucine rich repeat SH3_1 PF00018.28 EIM80485.1 - 2.7e-18 65.3 2.5 1.7e-08 34.0 0.2 3.5 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EIM80485.1 - 6.2e-13 48.4 5.7 3.4e-06 26.8 0.2 3.3 3 1 0 3 3 3 2 Variant SH3 domain SAM_2 PF07647.17 EIM80485.1 - 3.6e-11 43.0 0.0 1.1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EIM80485.1 - 2.1e-08 34.5 0.6 3.3e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 EIM80485.1 - 2.3e-07 31.4 0.2 8e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.17 EIM80485.1 - 3.5e-07 29.8 0.7 0.001 18.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 EIM80485.1 - 0.00053 20.2 6.8 0.02 15.2 1.1 2.9 3 0 0 3 3 3 2 Bacterial SH3 domain PX PF00787.24 EIM80488.1 - 1.5e-21 76.5 0.0 5.1e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EIM80488.1 - 0.00076 19.1 5.0 0.019 14.5 0.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like DUF4391 PF14335.6 EIM80488.1 - 0.075 12.7 0.7 0.19 11.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) BLOC1_2 PF10046.9 EIM80488.1 - 0.49 10.7 3.5 6.4 7.1 1.3 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 EIM80488.1 - 2.3 7.7 6.5 3.3 7.2 1.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit FliJ PF02050.16 EIM80488.1 - 5.5 7.2 13.7 0.72 10.1 4.3 2.9 2 1 0 2 2 2 0 Flagellar FliJ protein zf-C3HC4_3 PF13920.6 EIM80490.1 - 4.8e-10 39.1 5.5 4.8e-10 39.1 5.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM80490.1 - 1.4e-09 37.6 9.1 3.1e-09 36.5 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM80490.1 - 2.3e-08 34.2 8.7 2.3e-08 34.2 8.7 2.0 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM80490.1 - 2.7e-08 33.7 5.4 9.2e-08 32.0 5.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIM80490.1 - 3.2e-07 30.1 8.4 7e-07 29.0 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM80490.1 - 1.4e-06 28.4 8.1 3.1e-06 27.2 8.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EIM80490.1 - 5.2e-06 26.3 7.2 6e-06 26.1 6.0 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM80490.1 - 9e-06 25.5 6.9 2.8e-05 23.9 6.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2937 PF11157.8 EIM80490.1 - 0.025 14.3 0.5 0.04 13.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Csm1_N PF18504.1 EIM80490.1 - 0.029 14.7 3.6 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain G_path_suppress PF15991.5 EIM80490.1 - 0.032 14.4 11.0 0.054 13.6 11.0 1.4 1 1 0 1 1 1 0 G-protein pathway suppressor Troponin PF00992.20 EIM80490.1 - 0.041 14.2 2.3 0.066 13.5 2.3 1.2 1 0 0 1 1 1 0 Troponin VTC PF09359.10 EIM80490.1 - 0.06 12.7 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 VTC domain zf-RING_4 PF14570.6 EIM80490.1 - 0.075 12.8 6.1 0.18 11.6 6.1 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ADIP PF11559.8 EIM80490.1 - 0.11 12.5 4.4 0.19 11.8 4.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tnp_22_trimer PF17489.2 EIM80490.1 - 0.14 12.2 0.8 3.9 7.5 0.2 2.5 2 0 0 2 2 2 0 L1 transposable element trimerization domain Lebercilin PF15619.6 EIM80490.1 - 0.14 11.8 4.0 0.23 11.1 4.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease zf-RING_6 PF14835.6 EIM80490.1 - 0.15 11.9 2.6 0.71 9.8 3.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DivIC PF04977.15 EIM80490.1 - 0.22 11.3 1.9 14 5.6 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.6 EIM80490.1 - 0.31 10.3 2.9 1.4 8.2 2.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-RING_11 PF17123.5 EIM80490.1 - 0.62 9.9 5.2 1.8 8.4 5.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger Golgin_A5 PF09787.9 EIM80490.1 - 0.73 9.2 5.6 1.2 8.6 5.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EIM80490.1 - 0.8 9.8 5.0 1.3 9.1 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SKA2 PF16740.5 EIM80490.1 - 4.4 7.1 7.7 6.1 6.7 0.4 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 zf-piccolo PF05715.13 EIM80490.1 - 8.2 6.7 7.7 6.9 6.9 2.7 2.8 2 1 1 3 3 3 0 Piccolo Zn-finger zf-C3HC4_3 PF13920.6 EIM80491.1 - 2.8e-10 39.9 6.5 4.4e-10 39.3 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM80491.1 - 2.8e-10 40.1 3.3 2.8e-10 40.1 3.3 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM80491.1 - 3.1e-09 36.8 10.2 5.7e-09 36.0 10.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EIM80491.1 - 3.5e-09 36.4 8.6 5.9e-09 35.7 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM80491.1 - 1.3e-08 35.0 7.4 2.5e-08 34.1 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EIM80491.1 - 2.5e-08 33.7 6.7 4.5e-08 32.9 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM80491.1 - 9.3e-08 31.8 8.2 1.9e-07 30.8 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM80491.1 - 2e-06 27.5 8.0 3.6e-06 26.7 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 bZIP_1 PF00170.21 EIM80491.1 - 0.00066 19.7 2.4 0.0037 17.3 0.1 2.3 2 0 0 2 2 2 1 bZIP transcription factor zf-RING_6 PF14835.6 EIM80491.1 - 0.0017 18.2 3.7 0.0038 17.1 3.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein BLOC1_2 PF10046.9 EIM80491.1 - 0.0027 18.0 2.5 1.2 9.5 0.0 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.6 EIM80491.1 - 0.0042 17.2 0.3 0.0077 16.3 0.3 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 zf-rbx1 PF12678.7 EIM80491.1 - 0.021 15.1 4.0 0.021 15.1 4.0 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EIM80491.1 - 0.022 14.8 1.4 0.038 14.0 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Atg14 PF10186.9 EIM80491.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_10 PF16685.5 EIM80491.1 - 0.037 14.2 6.6 0.081 13.1 6.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 SHE3 PF17078.5 EIM80491.1 - 0.04 13.6 0.4 0.058 13.1 0.4 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 U-box PF04564.15 EIM80491.1 - 0.042 14.0 0.1 0.096 12.9 0.1 1.6 1 0 0 1 1 1 0 U-box domain zinc_ribbon_5 PF13719.6 EIM80491.1 - 0.047 13.5 0.3 0.12 12.2 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain ZapB PF06005.12 EIM80491.1 - 0.056 13.9 2.1 1.8 9.1 2.1 2.2 1 1 0 1 1 1 0 Cell division protein ZapB zinc_ribbon_4 PF13717.6 EIM80491.1 - 0.065 13.2 2.5 0.22 11.5 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain CENP-H PF05837.12 EIM80491.1 - 0.075 13.5 2.3 0.13 12.7 2.3 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) T3SSipB PF16535.5 EIM80491.1 - 0.084 13.4 2.7 0.14 12.6 2.7 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB Nup88 PF10168.9 EIM80491.1 - 0.14 10.0 0.5 0.18 9.6 0.5 1.0 1 0 0 1 1 1 0 Nuclear pore component zf-RING_11 PF17123.5 EIM80491.1 - 0.14 11.9 4.8 0.33 10.7 4.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EIM80491.1 - 0.24 11.2 7.4 0.88 9.4 7.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain YkyA PF10368.9 EIM80491.1 - 0.39 10.4 4.0 0.6 9.8 4.0 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein EzrA PF06160.12 EIM80491.1 - 0.49 8.5 3.4 1.5 6.9 3.5 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.8 EIM80491.1 - 0.82 9.9 5.5 7.2 6.9 5.5 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 EIM80491.1 - 0.99 9.5 4.0 3.3 7.8 4.0 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EIM80491.1 - 1.1 10.0 3.2 2.8 8.6 0.2 2.4 1 1 1 2 2 2 0 SlyX zf-MIZ PF02891.20 EIM80491.1 - 1.4 8.7 6.1 2.4 8.0 6.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.7 EIM80491.1 - 3 8.0 7.3 8.1 6.6 7.3 1.8 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 EIM80491.1 - 6.5 7.0 7.0 5.5 7.2 3.0 2.6 2 1 1 3 3 3 0 FYVE zinc finger DUF3584 PF12128.8 EIM80492.1 - 0.17 9.4 32.4 0.27 8.7 32.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 EIM80492.1 - 0.3 11.5 41.4 2.6 8.5 21.1 3.0 2 1 1 3 3 3 0 Fez1 FliJ PF02050.16 EIM80492.1 - 0.31 11.3 37.4 0.35 11.1 0.1 4.4 2 1 2 4 4 4 0 Flagellar FliJ protein ATG16 PF08614.11 EIM80492.1 - 0.49 10.6 38.0 0.53 10.5 6.3 3.9 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Tox-MPTase2 PF15638.6 EIM80492.1 - 1.2 8.8 3.9 1.1 8.9 1.1 2.1 2 0 0 2 2 2 0 Metallopeptidase toxin 2 COG5 PF10392.9 EIM80492.1 - 1.6 8.9 19.8 0.72 10.0 1.7 3.2 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Spc7 PF08317.11 EIM80492.1 - 5.8 5.7 41.6 0.15 10.9 21.2 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein NMO PF03060.15 EIM80493.1 - 2e-50 172.1 4.1 2.7e-50 171.6 4.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EIM80493.1 - 4.2e-08 32.6 0.6 2.4e-06 26.8 0.6 2.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EIM80493.1 - 0.7 8.9 6.8 1 8.3 6.8 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PS_Dcarbxylase PF02666.15 EIM80495.1 - 3.3e-41 141.1 0.0 4.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EIM80495.1 - 3.5e-34 117.8 0.0 6.3e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Peptidase_M23 PF01551.22 EIM80495.1 - 0.16 12.2 0.1 1.5 9.1 0.0 2.5 3 0 0 3 3 3 0 Peptidase family M23 Oxidored_FMN PF00724.20 EIM80496.1 - 1.3e-70 238.3 0.0 1.7e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SAC3_GANP PF03399.16 EIM80497.1 - 9.8e-23 81.0 3.5 2.8e-13 49.9 0.4 2.2 1 1 1 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EIM80497.1 - 1e-09 38.5 0.2 5.2e-09 36.2 0.3 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 EIM80497.1 - 0.038 14.5 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 PCI domain Spc7 PF08317.11 EIM80497.1 - 0.083 11.8 0.1 0.083 11.8 0.1 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein NOA36 PF06524.12 EIM80498.1 - 0.24 10.7 14.7 0.31 10.3 14.7 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EIM80498.1 - 0.28 10.6 14.0 0.3 10.5 14.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIM80498.1 - 0.62 8.2 12.6 0.62 8.2 12.6 1.0 1 0 0 1 1 1 0 Nop14-like family DASH_Hsk3 PF08227.11 EIM80500.1 - 1.6e-06 28.4 2.3 2.4e-06 27.8 2.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like SDH_alpha PF03313.15 EIM80501.1 - 1.5e-102 342.7 1.6 2e-102 342.3 1.6 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 EIM80501.1 - 3.4e-56 189.9 0.0 5.9e-56 189.1 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain Velvet PF11754.8 EIM80502.1 - 3.9e-25 89.2 0.0 4.6e-12 46.4 0.0 2.3 1 1 1 2 2 2 2 Velvet factor TPR_1 PF00515.28 EIM80503.1 - 2.5e-17 61.9 0.9 2.9e-07 30.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM80503.1 - 7.4e-16 57.6 2.1 1.8e-06 27.5 0.1 4.4 2 2 2 4 4 4 3 TPR repeat TPR_2 PF07719.17 EIM80503.1 - 8.7e-16 56.7 2.1 9.1e-07 28.5 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM80503.1 - 5.9e-11 41.7 0.9 0.0051 16.9 0.0 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIM80503.1 - 9.3e-11 41.6 2.6 0.0089 16.8 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIM80503.1 - 2.1e-10 40.3 0.2 0.041 14.3 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EIM80503.1 - 6.3e-10 39.2 3.3 0.00034 20.9 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM80503.1 - 6.9e-10 39.3 0.5 5.6e-05 23.6 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM80503.1 - 2.5e-09 37.6 4.7 0.0031 18.1 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EIM80503.1 - 5.9e-07 29.2 3.2 0.033 14.0 0.0 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIM80503.1 - 1.7e-05 24.5 4.1 0.15 12.2 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EIM80503.1 - 2e-05 23.9 0.2 2.7e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIM80503.1 - 8.3e-05 23.0 0.1 0.057 14.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM80503.1 - 0.00045 20.4 0.8 0.046 13.9 0.1 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC5 PF12862.7 EIM80503.1 - 0.00066 19.7 0.3 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 MIT PF04212.18 EIM80503.1 - 0.0052 16.8 1.2 16 5.7 0.1 3.4 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EIM80503.1 - 0.0054 17.2 0.5 0.0054 17.2 0.5 3.5 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EIM80503.1 - 0.013 15.8 2.8 0.05 13.9 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EIM80503.1 - 0.016 15.3 0.7 3.1 8.0 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 EIM80503.1 - 0.016 15.3 0.4 5.2 7.1 0.1 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_MalT PF17874.1 EIM80503.1 - 0.022 14.1 0.3 0.45 9.8 0.1 2.4 1 1 0 2 2 2 0 MalT-like TPR region HCMVantigenic_N PF12154.8 EIM80503.1 - 3.3 7.9 5.4 0.77 9.9 1.3 2.1 2 0 0 2 2 1 0 Glycoprotein B N-terminal antigenic domain of HCMV FAD_binding_3 PF01494.19 EIM80504.1 - 6.3e-23 81.6 0.0 1.5e-22 80.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EIM80504.1 - 7.1e-07 28.4 0.1 3e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EIM80504.1 - 0.00045 20.4 1.3 0.001 19.3 1.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM80504.1 - 0.0029 16.9 0.5 0.0062 15.8 0.5 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM80504.1 - 0.0081 14.9 1.7 0.012 14.4 1.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM80504.1 - 0.065 12.5 2.9 2.9 7.1 2.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM80504.1 - 0.081 13.5 0.4 0.19 12.3 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM80504.1 - 0.18 11.1 1.1 0.34 10.1 1.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EIM80504.1 - 0.25 10.4 1.9 0.43 9.6 1.9 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EIM80504.1 - 0.28 10.2 1.0 0.39 9.8 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 EIM80504.1 - 0.29 10.7 6.8 0.2 11.2 5.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM80504.1 - 0.38 10.7 1.6 33 4.4 0.9 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Cytochrom_C1 PF02167.15 EIM80505.1 - 3.2e-97 324.5 0.0 4e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EIM80505.1 - 0.001 19.3 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EIM80505.1 - 0.032 15.4 0.1 0.081 14.1 0.1 2.0 1 1 0 1 1 1 0 Cytochrome c CYSTM PF12734.7 EIM80506.1 - 0.0043 17.4 67.4 1.8e+04 -9.9 67.4 4.1 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 EIM80506.1 - 8.9 6.3 20.8 12 5.8 20.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Tri3 PF07428.11 EIM80508.1 - 3.1e-08 32.9 0.0 4.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 Cadherin_C_2 PF16492.5 EIM80509.1 - 0.2 12.5 3.1 25 5.7 1.7 2.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal FixQ PF05545.11 EIM80509.1 - 5.7 7.0 5.5 0.93 9.5 0.1 2.6 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ CPSase_L_D2 PF02786.17 EIM80510.1 - 1.5e-79 266.4 0.1 3.6e-79 265.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EIM80510.1 - 1e-68 231.0 0.0 1.8e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EIM80510.1 - 2.3e-40 137.5 0.1 4.8e-40 136.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EIM80510.1 - 3.6e-30 104.2 0.0 1.3e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EIM80510.1 - 4.2e-28 98.7 0.0 9.8e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EIM80510.1 - 1.8e-19 69.3 6.4 2.8e-17 62.3 3.0 2.8 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EIM80510.1 - 7.9e-13 48.0 3.1 1.1e-06 28.4 0.0 2.9 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EIM80510.1 - 1.1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EIM80510.1 - 1.9e-06 27.6 0.1 4.2e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EIM80510.1 - 4.3e-06 27.4 0.9 0.13 13.0 0.2 3.0 3 0 0 3 3 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EIM80510.1 - 7.1e-06 25.4 0.7 0.002 17.4 0.1 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 EIM80510.1 - 9.4e-05 22.5 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 EIM80510.1 - 0.00048 20.0 2.1 0.0039 17.1 0.3 3.2 3 1 1 4 4 4 1 Glycine cleavage H-protein NQRA PF05896.11 EIM80510.1 - 0.0036 16.8 0.3 0.0071 15.8 0.3 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_4 PF13535.6 EIM80510.1 - 0.0047 16.5 0.1 0.0097 15.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 EIM80510.1 - 0.0064 16.5 0.1 0.3 11.0 0.2 2.8 2 1 1 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 EIM80510.1 - 0.0073 16.3 1.4 0.027 14.4 0.7 2.3 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain GARS_A PF01071.19 EIM80510.1 - 0.029 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EIM80510.1 - 0.034 13.4 0.0 0.081 12.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Peptidase_M23 PF01551.22 EIM80510.1 - 0.081 13.2 0.3 1.7 8.9 0.3 3.2 1 1 0 1 1 1 0 Peptidase family M23 PNPase PF03726.14 EIM80510.1 - 0.089 13.3 0.1 0.28 11.7 0.1 1.9 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PTS_EIIA_1 PF00358.20 EIM80510.1 - 0.11 12.3 0.1 0.66 9.7 0.1 2.3 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 LSM PF01423.22 EIM80511.1 - 2.2e-16 59.3 0.0 2.9e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ecl1 PF12855.7 EIM80513.1 - 0.00013 23.2 34.4 0.00046 21.4 34.4 1.9 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins SHR3_chaperone PF08229.11 EIM80514.1 - 2.4e-43 147.3 0.3 2.6e-43 147.2 0.3 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RhoGAP PF00620.27 EIM80515.1 - 9.1e-42 142.4 0.0 2e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EIM80515.1 - 1.4e-16 60.9 0.0 3.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 EIM80515.1 - 5.3e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 EIM80515.1 - 2e-06 28.2 0.0 4.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EIM80515.1 - 0.0088 16.3 0.0 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain KASH_CCD PF14662.6 EIM80515.1 - 0.02 14.7 0.3 0.034 14.0 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Ras PF00071.22 EIM80516.1 - 1.6e-51 174.2 0.0 2.1e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM80516.1 - 8.6e-21 74.4 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM80516.1 - 1.6e-07 30.9 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIM80516.1 - 0.00091 18.7 0.0 0.0023 17.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EIM80516.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM80516.1 - 0.023 14.6 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 EIM80516.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DLIC PF05783.11 EIM80516.1 - 0.052 12.4 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 EIM80516.1 - 0.073 13.4 0.0 0.16 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.18 EIM80517.1 - 1.1e-17 64.0 0.0 2.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM80517.1 - 1.4e-05 25.1 10.1 2.8e-05 24.1 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.13 EIM80518.1 - 1.5e-42 145.7 0.2 1.5e-42 145.7 0.2 2.5 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain FlpD PF02662.16 EIM80518.1 - 0.23 11.5 2.6 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF1771 PF08590.10 EIM80519.1 - 8.7e-14 51.6 6.7 1.8e-13 50.6 6.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Torus PF16131.5 EIM80519.1 - 1.6e-06 28.8 3.4 3.7e-05 24.4 0.1 2.4 1 1 1 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 EIM80519.1 - 4.2e-06 26.6 8.8 0.00046 20.1 1.5 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EIM80519.1 - 5.1e-06 26.3 7.2 0.0021 17.9 0.7 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 EIM80519.1 - 2.2e-05 24.7 0.1 5.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Smr domain zf-CCCH_3 PF15663.5 EIM80519.1 - 0.00067 19.9 2.0 0.0018 18.4 2.0 1.6 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EIM80519.1 - 0.0012 19.2 6.0 0.12 12.8 0.9 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 EIM80519.1 - 0.002 17.8 5.1 0.12 12.1 0.9 2.5 2 0 0 2 2 2 2 Putative zinc-finger domain zf-CCCH_4 PF18044.1 EIM80519.1 - 0.0043 16.8 12.2 0.28 11.0 0.9 3.3 2 1 0 2 2 2 2 CCCH-type zinc finger HBS1_N PF08938.10 EIM80519.1 - 0.14 12.4 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 HBS1 N-terminus EIF_2_alpha PF07541.12 EIM80520.1 - 5.3e-36 123.2 0.0 8.8e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EIM80520.1 - 2.5e-13 50.2 1.0 4.1e-13 49.5 1.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain pPIWI_RE_X PF13111.6 EIM80520.1 - 0.013 14.7 0.2 0.02 14.1 0.2 1.2 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain EF-hand_9 PF14658.6 EIM80520.1 - 0.029 14.7 0.1 0.079 13.3 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain FH2 PF02181.23 EIM80521.1 - 1.5e-05 24.3 7.9 0.003 16.7 0.2 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain Atg14 PF10186.9 EIM80521.1 - 0.00069 18.8 4.5 0.032 13.3 1.1 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EIM80521.1 - 0.0012 19.2 18.1 0.24 11.6 15.5 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EIM80521.1 - 0.0014 19.1 17.8 0.13 12.8 11.8 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region Fez1 PF06818.15 EIM80521.1 - 0.0015 19.0 5.3 0.048 14.1 1.4 2.1 2 0 0 2 2 2 1 Fez1 Tropomyosin PF00261.20 EIM80521.1 - 0.054 12.8 24.0 0.042 13.2 15.1 2.1 2 0 0 2 2 2 0 Tropomyosin TPR_MLP1_2 PF07926.12 EIM80521.1 - 0.055 13.5 25.0 0.89 9.6 3.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EIM80521.1 - 0.064 12.1 18.7 0.14 11.0 0.5 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 EIM80521.1 - 0.064 11.8 6.0 1.8 7.0 4.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Phage_GPO PF05929.11 EIM80521.1 - 0.094 12.3 3.7 0.72 9.4 0.8 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FPP PF05911.11 EIM80521.1 - 0.17 10.1 11.0 0.4 8.8 7.1 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 EIM80521.1 - 0.19 11.2 13.5 2.2 7.7 9.6 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Metal_resist PF13801.6 EIM80521.1 - 0.3 11.3 14.3 0.48 10.6 4.9 2.8 3 0 0 3 3 2 0 Heavy-metal resistance MscS_porin PF12795.7 EIM80521.1 - 0.4 10.2 25.2 1.2 8.6 17.7 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Seryl_tRNA_N PF02403.22 EIM80521.1 - 0.5 10.6 12.5 2.2 8.6 5.7 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 EIM80521.1 - 0.55 11.2 18.3 6.9 7.6 0.5 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 EIM80521.1 - 0.6 10.8 7.9 11 6.7 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Phage_GP20 PF06810.11 EIM80521.1 - 0.8 9.5 9.6 2 8.2 4.0 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 SKA1 PF07160.12 EIM80521.1 - 0.82 9.5 6.0 8.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF5339 PF17274.2 EIM80521.1 - 1 10.3 6.5 12 6.8 0.2 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5339) DMPK_coil PF08826.10 EIM80521.1 - 1 9.5 15.5 1.8 8.7 8.9 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like Uso1_p115_C PF04871.13 EIM80521.1 - 1 9.7 18.7 5 7.5 1.6 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BST2 PF16716.5 EIM80521.1 - 1.1 9.9 17.0 8.3 7.1 0.6 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 TMF_TATA_bd PF12325.8 EIM80521.1 - 1.3 9.2 18.4 5.2 7.3 1.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 EIM80521.1 - 1.9 8.1 18.2 0.36 10.5 0.4 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EIM80521.1 - 2.1 7.6 16.0 7.3 5.9 0.2 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 EIM80521.1 - 2.3 8.3 24.1 0.72 9.9 2.4 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.8 EIM80521.1 - 2.5 5.5 12.8 2.2 5.7 7.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TSNAXIP1_N PF15739.5 EIM80521.1 - 4.2 7.8 12.8 3 8.2 7.2 2.6 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus HAUS6_N PF14661.6 EIM80521.1 - 4.5 6.8 9.9 0.99 8.9 3.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Fib_alpha PF08702.10 EIM80521.1 - 5.1 7.3 8.8 27 4.9 5.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 EIM80521.1 - 5.2 6.8 14.0 0.38 10.6 7.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 EIM80521.1 - 5.4 7.2 20.8 3.5 7.8 0.8 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4140 PF13600.6 EIM80521.1 - 5.7 7.4 16.3 3.4 8.2 0.0 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) PEP-utilisers_N PF05524.13 EIM80521.1 - 5.8 7.1 12.7 0.95 9.6 0.3 2.7 3 0 0 3 3 2 0 PEP-utilising enzyme, N-terminal Swi5 PF07061.11 EIM80521.1 - 6.6 6.9 14.6 0.18 11.9 0.8 2.9 2 1 0 2 2 2 0 Swi5 ADIP PF11559.8 EIM80521.1 - 7.4 6.6 16.7 7.8 6.6 8.9 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GBP_C PF02841.14 EIM80521.1 - 7.6 5.8 16.1 1.4 8.3 9.5 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF4201 PF13870.6 EIM80521.1 - 8.8 6.0 13.9 17 5.1 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Fungal_trans PF04082.18 EIM80522.1 - 6e-15 55.0 0.3 1.1e-14 54.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM80522.1 - 0.00017 21.7 8.4 0.0003 20.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clathrin PF00637.20 EIM80523.1 - 1.7e-207 679.6 30.5 2.3e-32 111.8 0.2 7.7 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EIM80523.1 - 4.1e-35 118.4 0.1 8.5e-07 29.0 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EIM80523.1 - 2.3e-31 107.5 0.1 9.7e-31 105.5 0.1 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 EIM80523.1 - 1.3e-10 40.5 1.7 5.6e-10 38.4 0.1 2.8 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Vps39_1 PF10366.9 EIM80523.1 - 0.0011 19.2 8.8 1.2 9.5 0.3 6.3 7 0 0 7 7 7 2 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.6 EIM80523.1 - 0.0016 19.1 15.5 0.88 10.6 0.2 8.9 9 1 1 10 10 8 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EIM80523.1 - 0.0049 16.0 8.0 1 8.4 0.1 4.5 4 1 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 EIM80523.1 - 0.0075 16.0 4.8 21 5.1 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Acetyltransf_15 PF17013.5 EIM80523.1 - 0.039 13.4 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Putative acetyl-transferase TPR_7 PF13176.6 EIM80523.1 - 0.53 10.4 9.5 9.5 6.5 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM80523.1 - 1.9 8.8 13.0 69 3.9 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM80523.1 - 3.8 8.0 8.3 7.8 7.0 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_fungal PF17667.1 EIM80524.1 - 3.4e-45 154.5 0.0 6e-26 91.1 0.1 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EIM80524.1 - 4.8e-08 33.2 0.0 1.3e-06 28.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM80524.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NIR_SIR PF01077.22 EIM80525.1 - 2.1e-54 183.3 0.0 1.8e-48 164.1 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EIM80525.1 - 3.4e-32 110.1 0.0 8.5e-15 54.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EIM80525.1 - 4.6e-29 101.5 0.1 9.1e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EIM80525.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.7 EIM80525.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Cation_efflux PF01545.21 EIM80526.1 - 2.5e-39 135.1 36.5 2.5e-38 131.8 36.5 2.5 1 1 0 1 1 1 1 Cation efflux family V_ATPase_I PF01496.19 EIM80526.1 - 9.7 4.0 8.9 0.93 7.3 2.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Rcd1 PF04078.13 EIM80527.1 - 3e-125 416.7 3.3 3.4e-125 416.6 3.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cofilin_ADF PF00241.20 EIM80528.1 - 2.3e-08 33.9 0.0 4.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 EIM80528.1 - 0.00096 19.6 0.1 0.0033 17.9 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EIM80528.1 - 0.02 15.3 0.7 0.055 13.9 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Borrelia_P83 PF05262.11 EIM80528.1 - 0.029 12.9 14.8 0.032 12.7 14.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DDHD PF02862.17 EIM80528.1 - 0.47 10.6 3.8 0.81 9.8 3.8 1.4 1 0 0 1 1 1 0 DDHD domain Mus7 PF09462.10 EIM80529.1 - 3.7e-36 125.2 0.2 3.1e-35 122.1 0.2 2.1 1 1 0 1 1 1 1 Mus7/MMS22 family PQ-loop PF04193.14 EIM80530.1 - 8.6e-17 60.7 2.6 2.9e-10 39.7 0.8 2.9 2 0 0 2 2 2 2 PQ loop repeat Dimer_Tnp_hAT PF05699.14 EIM80532.1 - 0.021 14.6 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF563 PF04577.14 EIM80533.1 - 1.8e-19 70.7 0.3 3.5e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) MA3 PF02847.17 EIM80533.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 MA3 domain TPM_phosphatase PF04536.14 EIM80533.1 - 0.16 12.2 0.0 0.38 10.9 0.0 1.6 2 0 0 2 2 2 0 TPM domain RsgA_GTPase PF03193.16 EIM80533.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase ATG16 PF08614.11 EIM80534.1 - 6.5 6.9 8.8 0.34 11.1 1.9 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IGPS PF00218.21 EIM80535.1 - 3.6e-91 304.8 0.0 5.3e-91 304.3 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EIM80535.1 - 3.2e-47 160.8 0.0 1.3e-39 136.0 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EIM80535.1 - 8.1e-42 143.2 0.0 1.7e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIM80535.1 - 2.1e-06 27.7 0.1 6.9e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EIM80535.1 - 0.00037 20.3 0.8 0.0037 17.1 0.3 2.6 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain NMO PF03060.15 EIM80535.1 - 0.031 13.7 7.1 0.83 9.0 0.1 2.5 2 0 0 2 2 2 0 Nitronate monooxygenase PhoLip_ATPase_C PF16212.5 EIM80536.1 - 1.4e-76 257.6 23.5 1.4e-76 257.6 23.5 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIM80536.1 - 8.7e-26 89.4 4.8 2.9e-25 87.7 4.8 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EIM80536.1 - 1.5e-12 48.2 0.6 4.9e-07 30.2 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIM80536.1 - 5.8e-11 42.3 0.0 2.3e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EIM80536.1 - 2.6e-07 30.3 0.0 1.3e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EIM80536.1 - 0.0042 16.9 0.5 0.016 15.0 0.2 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase KIF1B PF12423.8 EIM80536.1 - 7.6 7.1 6.8 4.4 7.8 4.1 2.1 2 0 0 2 2 2 0 Kinesin protein 1B Abhydrolase_1 PF00561.20 EIM80537.1 - 1.4e-13 51.1 0.0 6.8e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM80537.1 - 4.6e-07 29.4 0.0 1.4e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EIM80537.1 - 0.0091 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DPBB_1 PF03330.18 EIM80538.1 - 2.6e-09 37.2 0.0 3.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase PB1 PF00564.24 EIM80539.1 - 3.2e-13 49.4 0.0 5.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 EIM80539.1 - 2.2e-10 39.9 3.7 0.0018 18.0 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM80539.1 - 1e-08 34.7 3.1 0.0046 17.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM80539.1 - 9.8e-08 32.2 0.7 7.7e-05 22.9 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM80539.1 - 2.4e-07 30.3 7.2 0.0064 16.5 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM80539.1 - 0.0036 16.9 0.1 0.0036 16.9 0.1 3.0 3 1 1 4 4 4 1 TPR repeat TPR_7 PF13176.6 EIM80539.1 - 0.0041 17.0 1.0 0.88 9.8 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIM80539.1 - 0.0067 16.3 0.2 0.71 9.8 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM80539.1 - 3 8.6 7.0 2.1 9.1 0.7 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat IGPD PF00475.18 EIM80540.1 - 7.5e-61 204.6 0.2 1.1e-60 204.2 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase GIT_SHD PF08518.11 EIM80541.1 - 5.4e-23 80.3 15.8 1.9e-13 49.8 2.6 3.1 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT Lebercilin PF15619.6 EIM80541.1 - 0.18 11.4 18.3 0.63 9.7 13.2 2.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EIM80541.1 - 0.46 10.5 7.1 6.4 6.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF5339 PF17274.2 EIM80541.1 - 1.1 10.1 5.2 13 6.7 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Exonuc_VII_L PF02601.15 EIM80541.1 - 6 6.3 12.7 8 5.9 9.0 3.0 2 1 0 2 2 2 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 EIM80541.1 - 9.2 6.4 25.8 1.9 8.6 13.8 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Noelin-1 PF12308.8 EIM80541.1 - 9.7 6.2 11.4 6.7 6.8 1.4 3.3 3 0 0 3 3 3 0 Neurogenesis glycoprotein Abhydrolase_1 PF00561.20 EIM80542.1 - 1.9e-22 80.1 0.0 4e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EIM80542.1 - 2.3e-21 75.1 0.0 4.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EIM80542.1 - 0.0066 15.7 0.0 0.12 11.7 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EIM80542.1 - 0.0093 15.6 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) p450 PF00067.22 EIM80543.1 - 4.2e-24 85.1 0.0 4.5e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.28 EIM80544.1 - 1.3e-29 103.4 0.0 2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM80544.1 - 1.3e-09 38.0 0.1 3.3e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM80544.1 - 4.6e-05 23.2 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TP_methylase PF00590.20 EIM80545.1 - 7.9e-20 71.7 0.0 1.3e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_2 PF00152.20 EIM80546.1 - 5.1e-87 291.9 0.0 6.9e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIM80546.1 - 6.1e-11 42.2 0.1 1.6e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain FMN_red PF03358.15 EIM80546.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Glyco_hydro_28 PF00295.17 EIM80548.1 - 4.3e-60 203.5 14.6 6e-60 203.0 14.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 p450 PF00067.22 EIM80550.1 - 1.7e-51 175.4 0.0 2e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM80551.1 - 1.8e-09 36.8 0.0 2.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4097 PF13349.6 EIM80554.1 - 0.042 13.2 1.8 0.2 11.0 0.4 2.4 2 1 0 2 2 2 0 Putative adhesin DUF5321 PF17254.2 EIM80555.1 - 0.00021 20.8 0.2 0.00026 20.5 0.2 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5321) BTB PF00651.31 EIM80557.1 - 6.2e-07 29.6 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Clathrin_lg_ch PF01086.17 EIM80558.1 - 1.7e-40 139.6 0.8 1.8e-40 139.4 0.8 1.1 1 0 0 1 1 1 1 Clathrin light chain RR_TM4-6 PF06459.12 EIM80558.1 - 0.65 9.8 6.1 0.91 9.3 6.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2263 PF10021.9 EIM80559.1 - 1.3e-39 135.9 0.0 2.3e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Hydrolase_4 PF12146.8 EIM80560.1 - 4.6e-56 189.8 0.0 5.4e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM80560.1 - 3.7e-12 47.3 0.0 5.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM80560.1 - 1.6e-07 31.2 1.9 2.9e-05 23.9 1.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM80560.1 - 3.4e-05 23.4 0.2 0.15 11.5 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 EIM80560.1 - 0.00059 19.6 0.0 0.0016 18.2 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 EIM80560.1 - 0.0015 17.3 0.1 0.49 9.0 0.0 2.8 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) DUF1749 PF08538.10 EIM80560.1 - 0.0019 17.3 0.0 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) LIDHydrolase PF10230.9 EIM80560.1 - 0.0021 17.6 0.0 0.0039 16.8 0.0 1.5 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DLH PF01738.18 EIM80560.1 - 0.0024 17.5 0.1 0.2 11.2 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EIM80560.1 - 0.0038 16.2 0.0 0.07 12.0 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EIM80560.1 - 0.0054 16.6 0.0 0.011 15.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EIM80560.1 - 0.0092 15.7 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.16 EIM80560.1 - 0.044 13.6 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 EIM80560.1 - 0.14 11.4 0.0 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) F-box-like PF12937.7 EIM80561.1 - 3.2e-12 46.1 1.4 2e-11 43.6 0.7 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM80561.1 - 9.9e-05 22.6 1.1 40 4.8 0.2 5.6 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EIM80561.1 - 0.046 13.6 3.2 6.3 6.8 0.2 3.5 3 0 0 3 3 3 0 F-box domain PGP_phosphatase PF09419.10 EIM80562.1 - 1.4e-43 148.4 0.0 1.9e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EIM80562.1 - 0.0084 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_10 PF00331.20 EIM80563.1 - 1.9e-97 326.3 1.0 2.2e-97 326.0 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EIM80563.1 - 8.4e-12 44.8 13.1 8.4e-12 44.8 13.1 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain HNH_2 PF13391.6 EIM80564.1 - 0.00042 20.4 0.0 0.00092 19.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease GST_N_2 PF13409.6 EIM80566.1 - 1.1e-18 67.3 0.0 2.5e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM80566.1 - 2.9e-17 62.8 0.0 6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM80566.1 - 4.7e-12 46.1 0.1 9.8e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM80566.1 - 3.5e-06 26.9 0.0 8.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM80566.1 - 0.0045 17.2 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EIM80566.1 - 0.0064 17.1 0.0 0.0095 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM80566.1 - 0.023 15.4 0.0 0.052 14.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Misat_Tub_SegII PF10644.9 EIM80567.1 - 1.4e-33 115.7 0.1 2.9e-33 114.7 0.0 1.6 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EIM80567.1 - 5.6e-30 104.4 0.0 8.4e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 EIM80567.1 - 4e-07 30.4 0.0 0.00048 20.4 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Abhydrolase_3 PF07859.13 EIM80568.1 - 2.7e-37 128.7 0.0 1e-31 110.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM80568.1 - 7.1e-10 38.3 0.0 1.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF1010 PF06231.11 EIM80568.1 - 0.091 13.3 1.0 0.27 11.8 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) Glyco_hydro_12 PF01670.16 EIM80569.1 - 2e-41 142.4 12.2 2.2e-41 142.2 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Abhydrolase_3 PF07859.13 EIM80570.1 - 1.6e-48 165.4 0.0 1.9e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM80570.1 - 4.3e-06 25.9 0.2 1.8e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM80571.1 - 1.4e-42 146.0 0.0 2.8e-42 145.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM80571.1 - 1.6e-06 27.3 0.1 1.2e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Foie-gras_1 PF11817.8 EIM80572.1 - 3e-40 138.4 2.5 8.4e-39 133.7 1.0 2.9 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 EIM80572.1 - 1.6e-08 33.8 0.0 3.5e-08 32.7 0.0 1.5 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 EIM80572.1 - 0.00012 22.0 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_12 PF13424.6 EIM80572.1 - 0.00071 19.8 0.2 0.0068 16.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIM80572.1 - 0.0096 15.8 0.1 0.075 12.9 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM80572.1 - 0.024 14.5 1.0 0.054 13.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM80572.1 - 0.039 14.6 0.8 0.13 12.9 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM80572.1 - 0.057 13.5 0.3 0.057 13.5 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM80572.1 - 0.13 12.4 0.2 0.71 10.0 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Transglut_C PF00927.22 EIM80572.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain TPR_8 PF13181.6 EIM80572.1 - 0.18 12.1 0.0 0.69 10.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2079 PF09852.9 EIM80573.1 - 0.074 11.9 0.5 0.071 12.0 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) F-box-like PF12937.7 EIM80574.1 - 3.1e-09 36.6 0.4 7.7e-09 35.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like ABC_membrane PF00664.23 EIM80576.1 - 6.6e-54 183.4 1.7 1.1e-53 182.7 1.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIM80576.1 - 3.1e-29 102.2 0.0 8.2e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EIM80576.1 - 0.00025 20.6 1.2 0.0097 15.4 1.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIM80576.1 - 0.002 18.5 0.3 0.0092 16.4 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 EIM80576.1 - 0.0059 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 EIM80576.1 - 0.012 14.9 0.0 0.046 13.0 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 EIM80576.1 - 0.08 12.7 0.5 8.2 6.1 0.0 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM80576.1 - 0.088 12.6 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SUR7 PF06687.12 EIM80577.1 - 5e-13 49.2 18.6 7.5e-13 48.6 18.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family Hum_adeno_E3A PF05393.11 EIM80577.1 - 0.58 10.2 5.7 2.7 8.0 0.8 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Amastin PF07344.11 EIM80577.1 - 7.5 6.4 23.3 0.97 9.3 16.6 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein ubiquitin PF00240.23 EIM80578.1 - 1.5e-06 27.9 0.6 7.6e-06 25.6 0.6 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EIM80578.1 - 1.5e-05 25.4 0.3 6.3e-05 23.4 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain RAWUL PF16207.5 EIM80578.1 - 0.0024 18.5 0.0 0.0028 18.3 0.0 1.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 EIM80578.1 - 0.026 14.4 0.2 0.18 11.7 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EIM80578.1 - 0.028 14.4 0.2 0.24 11.4 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain HSP70 PF00012.20 EIM80579.1 - 1.3e-265 882.3 15.3 1.5e-265 882.1 15.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIM80579.1 - 8.5e-16 57.7 3.1 6.4e-14 51.5 1.5 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EIM80579.1 - 0.0025 17.6 0.0 0.007 16.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DMRL_synthase PF00885.19 EIM80579.1 - 0.04 13.8 0.2 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase FtsA PF14450.6 EIM80579.1 - 0.089 13.2 11.6 1.4 9.4 0.1 4.5 3 3 1 4 4 4 0 Cell division protein FtsA HXXSHH PF07586.11 EIM80579.1 - 0.19 11.3 3.6 0.45 10.0 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) PIN_12 PF16289.5 EIM80579.1 - 2.7 8.4 9.0 6.4 7.2 2.5 3.0 3 1 0 3 3 3 0 PIN domain APH PF01636.23 EIM80580.1 - 1.7e-40 139.4 0.0 2.4e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM80580.1 - 0.00025 20.7 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EIM80580.1 - 0.00035 20.0 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase HeLo PF14479.6 EIM80581.1 - 0.078 12.8 1.5 0.74 9.6 2.2 2.1 2 1 0 2 2 2 0 Prion-inhibition and propagation zf-TFIIB PF13453.6 EIM80581.1 - 0.66 9.3 5.1 1.8 7.9 3.3 2.7 2 1 1 3 3 3 0 Transcription factor zinc-finger Anti-TRAP PF15777.5 EIM80581.1 - 0.75 9.8 4.8 0.47 10.5 2.7 1.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Beta-lactamase PF00144.24 EIM80585.1 - 3.8e-41 141.4 0.3 5.8e-41 140.8 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EIM80585.1 - 7.5e-05 23.1 0.1 0.0008 19.8 0.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) Amidohydro_1 PF01979.20 EIM80587.1 - 4.4e-23 82.2 0.0 5.9e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM80587.1 - 3.5e-10 40.0 0.1 5e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Beta-lactamase PF00144.24 EIM80588.1 - 3e-64 217.4 0.9 3.5e-64 217.1 0.9 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EIM80588.1 - 0.081 12.3 0.0 8.1 5.8 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase SoxG PF04268.12 EIM80588.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family bZIP_1 PF00170.21 EIM80589.1 - 1.2e-09 38.1 2.9 1.2e-09 38.1 2.9 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EIM80589.1 - 2.3e-06 27.6 7.1 2.3e-06 27.6 7.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper ABC_tran_CTD PF16326.5 EIM80589.1 - 0.03 14.6 6.8 1.4 9.2 7.4 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain bZIP_Maf PF03131.17 EIM80589.1 - 0.25 11.9 2.3 0.27 11.8 0.2 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor ATG16 PF08614.11 EIM80589.1 - 0.56 10.4 5.8 1.1 9.5 5.8 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EIM80589.1 - 1.1 9.1 4.5 4.5 7.1 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 EIM80589.1 - 1.8 9.0 4.8 0.52 10.8 0.7 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) KIAA1430 PF13879.6 EIM80589.1 - 9.3 7.1 6.8 2.3 9.0 2.0 2.4 2 1 0 2 2 2 0 KIAA1430 homologue Acyl-CoA_dh_N PF02771.16 EIM80592.1 - 2.4e-27 95.8 0.0 4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EIM80592.1 - 1e-26 93.9 0.1 1.8e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIM80592.1 - 9e-21 73.9 0.0 1.8e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIM80592.1 - 0.00066 20.0 0.0 0.002 18.4 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EIM80592.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DNA_pol_B_thumb PF14791.6 EIM80593.1 - 1.9e-22 79.2 0.1 4.2e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EIM80593.1 - 4.1e-17 62.4 0.0 8.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 EIM80593.1 - 1.2e-07 32.0 0.0 7.6e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EIM80593.1 - 1.6e-07 31.1 0.0 3.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 EIM80593.1 - 0.0012 19.1 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 Pathogenicity locus IMS_HHH PF11798.8 EIM80593.1 - 0.035 14.5 0.0 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif HHH_5 PF14520.6 EIM80593.1 - 0.06 14.0 0.0 0.2 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain p450 PF00067.22 EIM80594.1 - 4.4e-65 220.2 0.0 1.9e-64 218.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Phage-MuB_C PF09077.11 EIM80594.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Mu B transposition protein, C terminal UPF0029 PF01205.19 EIM80595.1 - 5.7e-26 90.9 0.0 1.2e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Med11 PF10280.9 EIM80595.1 - 0.076 13.5 0.1 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 Mediator complex protein PRIMA1 PF16101.5 EIM80595.1 - 0.96 9.5 3.1 0.44 10.6 0.3 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pyrid_oxidase_2 PF13883.6 EIM80597.1 - 1.4e-28 99.9 0.0 2.1e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Steroid_dh PF02544.16 EIM80599.1 - 1.6e-30 106.0 1.6 4.4e-10 39.7 0.0 3.2 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EIM80599.1 - 7.2e-08 32.2 1.1 3.9e-07 29.8 1.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1761 PF08570.10 EIM80599.1 - 0.022 15.0 2.2 0.097 12.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF4436 PF14494.6 EIM80600.1 - 4.1e-11 42.7 3.7 4.1e-11 42.7 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4436) DUF3576 PF12100.8 EIM80600.1 - 0.042 14.0 0.0 6.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3576) GFA PF04828.14 EIM80601.1 - 2.3e-20 72.7 0.6 3e-20 72.3 0.6 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 EIM80601.1 - 0.008 15.8 2.5 0.19 11.4 0.1 2.3 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Cytochrom_C1 PF02167.15 EIM80601.1 - 0.065 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Nudix_N_2 PF14803.6 EIM80601.1 - 0.62 10.0 6.4 0.99 9.4 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal Lipase_GDSL PF00657.22 EIM80602.1 - 0.021 14.8 0.6 0.041 13.8 0.3 1.7 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIM80602.1 - 0.027 14.9 4.4 0.094 13.1 4.4 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family NUDIX PF00293.28 EIM80603.1 - 3e-12 46.7 1.4 6.8e-11 42.3 0.0 2.5 1 1 2 3 3 3 2 NUDIX domain F-box-like PF12937.7 EIM80604.1 - 2.6e-14 52.8 0.3 6.7e-14 51.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM80604.1 - 0.0028 17.5 5.7 0.011 15.6 1.1 3.8 3 1 0 3 3 3 1 F-box domain Peptidase_M24 PF00557.24 EIM80605.1 - 9.7e-56 188.8 0.0 1.3e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EIM80605.1 - 6.7e-21 74.3 0.0 1.2e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SIS PF01380.22 EIM80606.1 - 3.9e-64 214.4 0.1 3.9e-34 117.3 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EIM80606.1 - 3e-17 63.1 0.0 7.5e-17 61.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EIM80606.1 - 2.8e-13 49.8 0.0 8.1e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EIM80606.1 - 3.4e-06 26.2 0.0 5.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GST_C PF00043.25 EIM80607.1 - 5.6e-10 39.3 0.0 1.4e-09 38.0 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM80607.1 - 1.3e-08 35.1 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM80607.1 - 9.8e-08 32.3 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM80607.1 - 3.6e-06 27.2 0.0 6.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM80607.1 - 1.1e-05 25.5 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EIM80607.1 - 0.0088 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EIM80607.1 - 0.0094 16.0 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CBF PF03914.17 EIM80608.1 - 3.2e-38 131.4 0.0 3.2e-38 131.4 0.0 3.5 4 1 0 4 4 4 1 CBF/Mak21 family BUD22 PF09073.10 EIM80608.1 - 0.0036 16.7 21.2 0.0036 16.7 21.2 3.4 3 0 0 3 3 3 1 BUD22 Cnd1 PF12717.7 EIM80608.1 - 0.005 16.9 0.3 0.022 14.8 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EIM80608.1 - 0.013 14.1 0.0 0.34 9.4 0.2 2.1 2 0 0 2 2 2 0 Adaptin N terminal region DUF4470 PF14737.6 EIM80608.1 - 0.62 10.3 2.1 1 9.6 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4470) FAD_binding_3 PF01494.19 EIM80609.1 - 3.4e-17 62.7 0.0 5.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM80609.1 - 3e-06 26.7 1.4 0.00014 21.2 0.7 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM80609.1 - 5.1e-06 26.6 1.1 5.1e-06 26.6 1.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM80609.1 - 9.1e-06 25.5 5.6 0.00033 20.4 2.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM80609.1 - 0.00025 20.2 2.7 0.0004 19.6 2.7 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EIM80609.1 - 0.00056 19.3 2.1 0.011 15.0 1.2 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EIM80609.1 - 0.00069 18.6 1.9 0.27 10.0 1.5 2.3 1 1 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EIM80609.1 - 0.00072 18.7 0.9 0.084 11.9 1.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 EIM80609.1 - 0.00082 19.9 0.1 0.0086 16.6 0.2 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM80609.1 - 0.01 14.6 0.9 0.024 13.3 1.2 1.4 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EIM80609.1 - 0.026 13.8 0.4 0.044 13.0 0.4 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EIM80609.1 - 0.051 12.9 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 EIM80609.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 EIM80609.1 - 0.21 10.6 3.6 0.35 9.9 3.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EIM80609.1 - 0.23 11.4 0.8 5.3 7.0 0.3 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EIM80609.1 - 0.46 9.8 2.5 0.79 9.0 2.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4796 PF16044.5 EIM80610.1 - 0.25 10.9 2.0 0.58 9.7 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf-SNAP50_C PF12251.8 EIM80610.1 - 0.38 10.4 3.5 0.2 11.3 1.0 1.9 1 1 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Glyco_hydro_43 PF04616.14 EIM80611.1 - 2e-36 125.8 0.2 2.7e-36 125.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EIM80611.1 - 0.00017 21.3 1.0 0.19 11.2 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Siva PF05458.12 EIM80612.1 - 0.023 14.4 3.8 0.023 14.4 3.8 2.1 2 0 0 2 2 2 0 Cd27 binding protein (Siva) FYVE PF01363.21 EIM80612.1 - 1.8 8.8 14.7 3 8.0 0.7 2.6 2 1 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 EIM80612.1 - 2.2 8.5 12.1 1.3 9.2 1.9 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger GMC_oxred_N PF00732.19 EIM80613.1 - 3e-61 207.4 0.0 4.8e-33 114.8 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM80613.1 - 1.6e-39 135.7 0.0 2.7e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM80613.1 - 0.0012 19.1 1.6 0.0026 18.0 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM80613.1 - 0.0048 16.2 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EIM80613.1 - 0.0061 15.6 0.2 0.01 14.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EIM80613.1 - 0.01 15.4 0.2 0.055 13.0 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ENTH PF01417.20 EIM80614.1 - 3.6e-51 172.4 0.1 6.9e-51 171.5 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EIM80614.1 - 0.00025 20.2 0.0 0.00025 20.2 0.0 2.1 2 0 0 2 2 2 1 ANTH domain PIG-X PF08320.12 EIM80615.1 - 7.9e-38 130.5 0.0 9.3e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 HemY_N PF07219.13 EIM80615.1 - 0.2 11.9 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus PCI PF01399.27 EIM80616.1 - 6e-09 36.4 4.8 2.2e-07 31.3 0.0 3.7 4 0 0 4 4 4 2 PCI domain Glyco_hydro_16 PF00722.21 EIM80617.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SWM_repeat PF13753.6 EIM80617.1 - 0.04 14.1 0.2 0.08 13.1 0.1 1.5 1 1 0 1 1 1 0 Putative flagellar system-associated repeat Lipase_GDSL PF00657.22 EIM80618.1 - 0.00049 20.1 0.0 0.0052 16.8 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIM80618.1 - 0.033 14.6 6.8 0.23 11.8 6.8 2.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family SDA1 PF05285.12 EIM80619.1 - 7.5e-89 298.6 38.5 4.9e-88 295.9 29.9 2.6 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EIM80619.1 - 1.5e-24 86.1 0.2 9.2e-24 83.5 0.1 2.4 2 0 0 2 2 2 1 NUC130/3NT domain YL1 PF05764.13 EIM80619.1 - 0.022 14.9 0.2 0.022 14.9 0.2 3.2 2 1 0 2 2 2 0 YL1 nuclear protein SEP PF08059.13 EIM80620.1 - 1.7e-25 89.3 0.0 3.4e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EIM80620.1 - 5.4e-14 52.2 0.0 7.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain Cadherin_tail PF15974.5 EIM80620.1 - 0.19 12.0 2.5 2.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Methyltransf_2 PF00891.18 EIM80621.1 - 8.7e-23 80.7 0.0 2.2e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 EIM80621.1 - 0.00099 19.1 0.1 0.0034 17.4 0.1 1.9 1 0 0 1 1 1 1 Dimerisation domain RNA_Me_trans PF04252.13 EIM80622.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Sugar_tr PF00083.24 EIM80623.1 - 1.6e-125 419.5 21.4 1.8e-125 419.3 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM80623.1 - 7.8e-17 61.2 42.4 1.4e-10 40.6 21.5 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily YL1 PF05764.13 EIM80624.1 - 0.14 12.3 2.7 0.15 12.1 2.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein E7 PF00527.18 EIM80624.1 - 0.24 11.6 1.5 0.39 11.0 1.5 1.3 1 0 0 1 1 1 0 E7 protein, Early protein RNA_pol_3_Rpc31 PF11705.8 EIM80624.1 - 1.5 9.1 7.9 2.4 8.4 7.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 EIM80624.1 - 2.2 7.5 5.1 2.9 7.1 5.1 1.1 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 EIM80625.1 - 1.5e-51 175.6 0.0 2.2e-50 171.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EIM80626.1 - 4.3e-05 23.3 0.2 0.00011 22.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM80626.1 - 0.0012 18.7 1.3 0.0012 18.7 1.3 2.8 3 1 0 3 3 3 1 F-box domain Kdo PF06293.14 EIM80627.1 - 3.8e-08 32.9 0.0 8.4e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EIM80627.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 EIM80627.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM80627.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EIM80627.1 - 0.052 12.3 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EIM80627.1 - 0.07 12.7 0.0 2.1 7.9 0.1 2.2 1 1 1 2 2 2 0 RIO1 family DUF755 PF05501.11 EIM80629.1 - 0.17 12.2 11.8 0.37 11.1 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 EIM80629.1 - 0.28 10.8 10.3 0.42 10.2 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ion_trans PF00520.31 EIM80630.1 - 2.4e-123 410.2 84.3 2.6e-37 128.4 4.5 5.1 5 0 0 5 5 5 5 Ion transport protein DUF2981 PF11200.8 EIM80630.1 - 0.86 9.3 8.5 0.66 9.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2981) PKD_channel PF08016.12 EIM80630.1 - 3.8 6.1 74.9 0.02 13.6 10.8 7.6 6 2 2 8 8 8 0 Polycystin cation channel Glyco_hydro_16 PF00722.21 EIM80631.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sulfate_transp PF00916.20 EIM80632.1 - 1.7e-115 385.9 16.0 2.5e-115 385.3 16.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EIM80632.1 - 6.4e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EIM80632.1 - 0.0022 18.4 13.2 0.0067 16.8 2.9 3.1 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EIM80632.1 - 0.0058 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain ADH_zinc_N PF00107.26 EIM80633.1 - 1.4e-12 47.7 0.3 2.1e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM80633.1 - 6.7e-06 25.9 0.0 3.3e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EIM80633.1 - 0.00034 20.1 0.3 0.00057 19.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EIM80633.1 - 0.0071 15.9 0.3 0.011 15.4 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family AlaDh_PNT_C PF01262.21 EIM80633.1 - 0.092 12.0 4.9 0.11 11.8 3.4 1.6 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EIM80633.1 - 0.096 13.7 0.2 0.22 12.6 0.2 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Use1 PF09753.9 EIM80634.1 - 1.6e-16 60.8 0.7 5.1e-16 59.1 0.7 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 EIM80634.1 - 0.37 8.7 5.2 1.1 7.1 0.0 2.0 2 0 0 2 2 2 0 Prominin polyprenyl_synt PF00348.17 EIM80635.1 - 1e-81 273.8 0.0 6.5e-70 235.1 0.0 2.8 2 1 0 2 2 2 2 Polyprenyl synthetase COesterase PF00135.28 EIM80636.1 - 9e-94 315.2 0.0 1.4e-93 314.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM80636.1 - 1.2e-06 28.6 0.1 5.6e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold SurE PF01975.17 EIM80637.1 - 5.4e-40 137.3 3.3 7.5e-40 136.8 3.3 1.2 1 0 0 1 1 1 1 Survival protein SurE DUF3371 PF11851.8 EIM80638.1 - 0.54 11.3 4.0 1.9 9.6 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) HA2 PF04408.23 EIM80639.1 - 2.3e-24 85.7 0.0 5.3e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIM80639.1 - 9.3e-15 54.8 0.0 3e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIM80639.1 - 1.3e-11 44.9 0.0 7.3e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM80639.1 - 2.3e-08 34.0 0.1 4.9e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIM80639.1 - 0.00013 22.2 0.2 0.00063 20.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 EIM80639.1 - 0.00028 20.6 0.3 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EIM80639.1 - 0.00031 21.1 0.1 0.00067 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM80639.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EIM80639.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EIM80639.1 - 0.058 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EIM80639.1 - 0.087 12.3 0.1 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 EIM80639.1 - 0.12 12.4 0.1 7.2 6.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EIM80639.1 - 0.13 11.7 0.0 0.53 9.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 EIM80639.1 - 0.17 11.2 1.5 0.53 9.5 0.0 2.3 2 1 0 2 2 2 0 Zeta toxin Flavi_DEAD PF07652.14 EIM80639.1 - 0.19 11.7 0.2 1.6 8.7 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.6 EIM80639.1 - 0.25 11.8 0.8 0.5 10.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain IMUP PF15761.5 EIM80640.1 - 5.4 7.8 7.9 17 6.2 7.9 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Septin PF00735.18 EIM80641.1 - 1.9e-112 375.1 0.4 3e-112 374.5 0.4 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EIM80641.1 - 9.7e-08 32.1 0.0 2.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM80641.1 - 7.5e-06 25.9 3.9 1.2e-05 25.3 0.1 2.7 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EIM80641.1 - 8.3e-06 25.5 2.6 0.00042 19.9 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EIM80641.1 - 4.9e-05 23.5 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EIM80641.1 - 0.00033 21.1 0.1 0.0016 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM80641.1 - 0.0011 19.3 2.4 0.0027 18.0 0.1 2.5 2 2 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EIM80641.1 - 0.0016 18.2 1.7 0.11 12.3 0.1 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EIM80641.1 - 0.0021 18.6 0.4 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Ras PF00071.22 EIM80641.1 - 0.0033 17.0 0.3 0.014 15.0 0.3 2.1 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 EIM80641.1 - 0.0043 16.4 2.2 0.0089 15.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_7 PF12775.7 EIM80641.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EIM80641.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 EIM80641.1 - 0.024 14.4 0.3 0.058 13.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EIM80641.1 - 0.036 14.1 7.0 0.5 10.4 0.1 3.2 2 1 1 3 3 3 0 Dynamin family AAA_25 PF13481.6 EIM80641.1 - 0.042 13.4 0.8 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EIM80641.1 - 0.076 12.2 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.6 EIM80641.1 - 0.078 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EIM80641.1 - 0.079 12.5 0.1 0.26 10.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 EIM80641.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EIM80641.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 EIM80641.1 - 0.14 11.9 0.5 11 5.7 0.0 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FOXP-CC PF16159.5 EIM80641.1 - 0.14 12.8 1.3 0.38 11.4 1.3 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain AAA PF00004.29 EIM80641.1 - 0.45 11.0 2.7 2.9 8.3 0.2 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cep57_CLD_2 PF14197.6 EIM80641.1 - 0.99 9.5 8.9 0.12 12.5 3.8 2.2 2 0 0 2 2 1 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 EIM80641.1 - 6.2 7.3 15.4 0.57 10.7 9.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region TFIIIC_sub6 PF10419.9 EIM80643.1 - 9.2e-18 63.9 0.0 1.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Herpes_pp85 PF04637.12 EIM80643.1 - 0.0034 15.9 0.3 0.0048 15.4 0.3 1.1 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FoP_duplication PF13865.6 EIM80643.1 - 0.32 11.6 12.0 0.54 10.8 12.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FtsJ PF01728.19 EIM80644.1 - 4.7e-42 144.1 0.0 5.7e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase XK-related PF09815.9 EIM80645.1 - 0.13 11.3 7.4 0.17 10.9 7.4 1.2 1 0 0 1 1 1 0 XK-related protein DUF2919 PF11143.8 EIM80645.1 - 2.2 8.6 7.1 0.82 10.0 2.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2919) Glycogen_syn PF05693.13 EIM80646.1 - 0 1080.5 0.0 0 1080.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 EIM80646.1 - 2.7e-06 27.3 0.2 5.9e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EIM80646.1 - 1.5e-05 25.4 0.0 0.0019 18.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EIM80646.1 - 1.6e-05 24.5 0.0 0.00049 19.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EIM80646.1 - 0.00014 21.9 0.6 0.0003 20.8 0.6 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EIM80646.1 - 0.00059 20.3 0.2 0.0017 18.8 0.2 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain tRNA-synt_1b PF00579.25 EIM80647.1 - 1.5e-64 218.2 0.0 1.1e-63 215.4 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ank_2 PF12796.7 EIM80648.1 - 1.4e-14 54.4 0.1 8e-09 36.0 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM80648.1 - 7.4e-09 36.0 2.0 0.015 15.9 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.12 EIM80648.1 - 2.2e-08 34.2 0.4 7.7e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.6 EIM80648.1 - 6.8e-08 32.6 0.7 8.3e-05 22.8 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM80648.1 - 6.1e-07 29.3 2.2 0.9 10.3 0.0 5.2 5 0 0 5 5 4 2 Ankyrin repeat Ank PF00023.30 EIM80648.1 - 5.4e-06 26.6 0.2 0.3 11.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat AAA_16 PF13191.6 EIM80648.1 - 6.6e-06 26.6 0.0 6.9e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM80648.1 - 0.00013 22.2 0.0 0.001 19.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EIM80648.1 - 0.00017 20.9 0.0 0.00035 19.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Helo_like_N PF17111.5 EIM80648.1 - 0.061 12.7 0.9 0.14 11.5 0.0 2.2 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins ATPase PF06745.13 EIM80648.1 - 0.13 11.5 1.0 15 4.8 0.0 3.2 3 1 0 3 3 3 0 KaiC FUSC PF04632.12 EIM80648.1 - 0.65 8.5 3.7 0.36 9.3 0.3 2.1 3 0 0 3 3 3 0 Fusaric acid resistance protein family Spt5_N PF11942.8 EIM80649.1 - 2.2 9.3 7.5 0.14 13.2 0.4 2.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Cyt-b5 PF00173.28 EIM80650.1 - 1e-12 48.0 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BCL9 PF11502.8 EIM80650.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein BNR_4 PF15892.5 EIM80651.1 - 6.2e-59 199.6 0.2 7.7e-59 199.3 0.2 1.0 1 0 0 1 1 1 1 BNR repeat-containing family member DUF5124 PF17160.4 EIM80651.1 - 0.027 15.2 0.9 0.056 14.2 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5124) NrfD PF03916.14 EIM80653.1 - 3 7.4 17.0 2.7 7.5 13.1 2.0 1 1 0 2 2 2 0 Polysulphide reductase, NrfD SLATT_fungal PF18142.1 EIM80654.1 - 9.6e-34 116.0 0.9 1.5e-33 115.3 0.9 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain ATG22 PF11700.8 EIM80654.1 - 0.21 10.1 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Adeno_shaft PF00608.17 EIM80654.1 - 1.7 8.6 5.8 3.5 7.5 2.0 2.8 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) SLATT_fungal PF18142.1 EIM80655.1 - 9e-16 58.0 0.0 1.1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain NIBRIN_BRCT_II PF16508.5 EIM80656.1 - 0.0023 18.3 0.1 0.0081 16.5 0.1 2.0 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 PF16770.5 EIM80656.1 - 0.0085 16.0 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PQQ_2 PF13360.6 EIM80656.1 - 0.022 14.3 0.1 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain F-box-like PF12937.7 EIM80657.1 - 2.1e-09 37.1 0.2 2.1e-09 37.1 0.2 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM80657.1 - 2.2e-06 27.4 0.3 6.8e-06 25.8 0.3 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EIM80657.1 - 8 7.0 5.6 21 5.7 0.1 4.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) DPBB_1 PF03330.18 EIM80659.1 - 4.6e-06 26.8 0.1 8.6e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM80659.1 - 0.0033 17.2 0.1 0.0038 17.1 0.1 1.2 1 0 0 1 1 1 1 Barwin family Gal_Lectin PF02140.18 EIM80659.1 - 0.0082 16.5 0.1 0.0096 16.3 0.1 1.1 1 0 0 1 1 1 1 Galactose binding lectin domain DnaJ-X PF14308.6 EIM80660.1 - 5.8e-54 182.7 1.4 5.8e-54 182.7 1.4 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EIM80660.1 - 5.4e-27 93.7 2.1 1.6e-26 92.2 2.1 1.9 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_6 PF12697.7 EIM80661.1 - 2.9e-06 28.0 0.1 3.4e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM80661.1 - 0.0057 16.0 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EIM80661.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 EIM80661.1 - 0.09 12.4 0.2 0.22 11.1 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thaumatin PF00314.17 EIM80662.1 - 1.3e-72 243.9 8.6 1.5e-72 243.7 8.6 1.0 1 0 0 1 1 1 1 Thaumatin family DUF2062 PF09835.9 EIM80662.1 - 0.19 11.6 0.3 0.26 11.1 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) LRR_4 PF12799.7 EIM80663.1 - 0.0014 18.9 4.2 1.4 9.4 0.1 4.8 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) F-box PF00646.33 EIM80663.1 - 0.013 15.3 0.2 0.045 13.6 0.2 2.0 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 EIM80663.1 - 1.4 8.7 3.9 3.3 7.5 0.1 3.5 5 0 0 5 5 5 0 Leucine rich repeat Proteasome PF00227.26 EIM80664.1 - 9.3e-28 97.0 0.1 1.1e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 EIM80664.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Amnionless PF14828.6 EIM80665.1 - 0.0058 15.5 0.0 0.0087 14.9 0.0 1.1 1 0 0 1 1 1 1 Amnionless DUF1918 PF08940.11 EIM80665.1 - 0.067 12.8 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) SKG6 PF08693.10 EIM80665.1 - 1.2 8.6 5.9 3.2 7.2 5.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain JmjC PF02373.22 EIM80667.1 - 3.3e-39 133.8 0.1 8.4e-39 132.5 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EIM80667.1 - 1.2e-15 57.2 0.2 2.9e-15 55.9 0.2 1.8 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 EIM80667.1 - 1.1e-11 44.8 2.1 3e-11 43.4 2.1 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EIM80667.1 - 4.3e-09 36.5 7.3 1.3e-08 35.0 7.3 1.8 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 EIM80667.1 - 0.0014 18.5 2.3 0.0046 16.8 2.3 1.9 1 0 0 1 1 1 1 PHD-finger Bac_small_YrzI PF09501.10 EIM80667.1 - 0.32 11.1 0.9 0.84 9.8 0.9 1.7 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Pkinase PF00069.25 EIM80668.1 - 2.5e-38 131.9 0.0 3.8e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM80668.1 - 6.5e-19 68.2 0.0 8.8e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM80668.1 - 7.1e-08 32.1 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4692 PF15763.5 EIM80668.1 - 0.34 11.4 4.9 0.69 10.4 4.9 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) F-box-like PF12937.7 EIM80669.1 - 2.1e-07 30.7 0.1 5.2e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF1242 PF06842.12 EIM80670.1 - 5.3e-19 67.7 1.5 7.1e-19 67.3 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 EIM80670.1 - 0.17 12.2 2.9 0.33 11.3 2.1 1.7 1 1 0 2 2 2 0 LST-1 protein Alpha-amylase PF00128.24 EIM80671.1 - 3.5e-24 86.0 0.1 9.5e-24 84.6 0.1 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EIM80671.1 - 0.00027 19.3 0.1 0.13 10.4 0.1 2.9 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EIM80671.1 - 0.0039 17.3 0.7 0.012 15.8 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Glyco_hydro_88 PF07470.13 EIM80672.1 - 1.1e-18 67.4 1.6 1.8e-18 66.7 1.6 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MID_MedPIWI PF18296.1 EIM80672.1 - 0.071 12.9 2.0 2.5 7.9 1.1 2.3 2 0 0 2 2 2 0 MID domain of medPIWI SR-25 PF10500.9 EIM80672.1 - 0.56 9.8 12.5 0.84 9.2 12.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EIM80672.1 - 4.1 5.4 9.1 5.2 5.0 9.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pheromone PF08015.11 EIM80673.1 - 0.004 18.2 1.3 0.004 18.2 1.3 2.5 2 2 0 2 2 2 1 Fungal mating-type pheromone DUF294 PF03445.13 EIM80676.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Nop14 PF04147.12 EIM80677.1 - 0.044 12.0 5.0 0.051 11.8 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 EIM80677.1 - 0.08 12.9 2.3 0.14 12.1 2.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 EIM80677.1 - 3.2 7.3 14.8 7.6 6.1 14.8 1.6 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) CPSF100_C PF13299.6 EIM80677.1 - 5 7.3 6.2 4.7 7.4 5.2 1.5 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Trm112p PF03966.16 EIM80679.1 - 5.7e-20 71.7 0.0 6.9e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-ACC PF17848.1 EIM80679.1 - 0.051 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain PfkB PF00294.24 EIM80680.1 - 1.3e-07 31.2 0.0 0.026 13.8 0.0 3.0 3 0 0 3 3 3 2 pfkB family carbohydrate kinase p450 PF00067.22 EIM80681.1 - 3.7e-50 171.0 0.0 4e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM80682.1 - 2.1e-53 181.7 0.0 4.2e-53 180.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM80683.1 - 7e-50 170.1 0.0 8e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.18 EIM80684.1 - 1.4e-07 31.5 17.4 2.5e-07 30.7 17.4 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EIM80684.1 - 0.17 11.8 12.2 1.1 9.2 12.2 2.2 1 1 0 1 1 1 0 HIT zinc finger DUF1281 PF06924.11 EIM80684.1 - 0.26 10.8 1.2 0.98 8.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) zf-AN1 PF01428.16 EIM80684.1 - 0.28 11.4 6.0 0.48 10.6 5.6 1.7 1 1 0 1 1 1 0 AN1-like Zinc finger zf-Mss51 PF13824.6 EIM80684.1 - 0.84 9.8 5.6 1.6 8.9 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EIM80684.1 - 3.1 8.2 11.7 20 5.6 11.7 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding NIF PF03031.18 EIM80686.1 - 2.1e-17 63.3 0.0 3.3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RhlB PF12300.8 EIM80686.1 - 0.023 14.8 0.5 0.023 14.8 0.5 2.9 2 1 1 3 3 3 0 ATP-dependent RNA helicase RhlB AhpC-TSA PF00578.21 EIM80687.1 - 1.6e-37 128.2 0.0 2.3e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIM80687.1 - 4.8e-12 45.8 0.0 6.8e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EIM80687.1 - 1.1e-10 41.1 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin RNase_PH PF01138.21 EIM80688.1 - 7.9e-20 71.7 0.0 1.2e-19 71.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EIM80688.1 - 6.4e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 F-box-like PF12937.7 EIM80689.1 - 0.0013 18.5 0.1 0.0037 17.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM80689.1 - 0.069 13.0 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 F-box domain Hamartin PF04388.12 EIM80689.1 - 3.6 6.2 8.7 4.2 5.9 8.7 1.3 1 0 0 1 1 1 0 Hamartin protein DUF262 PF03235.14 EIM80690.1 - 1.6e-17 64.4 0.9 3.9e-17 63.2 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF262 adh_short PF00106.25 EIM80691.1 - 1.7e-23 83.1 0.0 3.3e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM80691.1 - 3.5e-17 62.8 0.0 1.9e-15 57.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM80691.1 - 0.00023 21.1 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EIM80692.1 - 5.1e-36 124.0 0.0 6.6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM80692.1 - 1.8e-27 96.4 0.0 2.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM80692.1 - 1.3e-06 28.5 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM80692.1 - 0.0004 19.8 0.0 0.00058 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EIM80692.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CTP_transf_like PF01467.26 EIM80693.1 - 4e-26 91.9 0.0 5.3e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Met_10 PF02475.16 EIM80693.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein HU-CCDC81_bac_1 PF18174.1 EIM80693.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 F-box-like PF12937.7 EIM80694.1 - 0.095 12.6 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like RAI1 PF08652.11 EIM80695.1 - 6.8e-06 26.2 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease His_Phos_2 PF00328.22 EIM80696.1 - 1.5e-05 24.5 0.0 3.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SRP_TPR_like PF17004.5 EIM80697.1 - 1.1e-13 51.3 0.6 1.4e-13 50.9 0.6 1.2 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 EIM80697.1 - 2.1e-10 40.8 0.5 2.1e-10 40.8 0.5 2.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 EIM80697.1 - 4.4e-09 36.4 4.3 3.6e-05 23.9 1.5 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EIM80697.1 - 2.8e-07 30.8 5.3 0.24 12.3 0.6 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM80697.1 - 5.1e-06 26.9 10.4 0.0014 19.1 4.8 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM80697.1 - 5.7e-06 26.9 1.6 0.0031 18.1 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM80697.1 - 4.7e-05 23.2 7.8 0.83 9.9 0.2 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EIM80697.1 - 0.0026 17.9 3.9 0.0052 16.9 0.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM80697.1 - 0.014 15.7 6.1 0.1 12.9 0.8 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EIM80697.1 - 0.017 15.5 0.6 8.9 6.8 0.1 2.6 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation TPR_15 PF13429.6 EIM80697.1 - 0.068 12.4 6.1 0.084 12.1 3.6 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM80697.1 - 0.074 13.7 6.2 10 7.0 0.6 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 EIM80697.1 - 0.083 11.8 2.7 1.9 7.3 0.1 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 EIM80697.1 - 0.093 12.8 2.0 3.7 7.7 0.0 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EIM80697.1 - 0.14 12.6 1.9 0.51 10.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EIM80697.1 - 2.4 8.5 6.1 19 5.7 1.1 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.13 EIM80698.1 - 4.4e-17 62.4 8.5 4.4e-17 62.4 8.5 4.1 3 1 1 4 4 4 2 pinin/SDK/memA/ protein conserved region TEA PF01285.18 EIM80699.1 - 3.7e-24 84.6 0.0 6e-23 80.7 0.0 2.3 2 0 0 2 2 2 1 TEA/ATTS domain zf-RING_13 PF17977.1 EIM80699.1 - 0.00079 19.5 0.4 0.0024 18.0 0.4 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain 7tm_2 PF00002.24 EIM80700.1 - 0.054 12.8 0.2 0.065 12.5 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Cellulase PF00150.18 EIM80701.1 - 0.00016 21.2 0.2 0.00026 20.5 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TTc_toxin_rep PF18807.1 EIM80702.1 - 0.093 12.6 0.1 0.38 10.6 0.0 2.0 2 1 0 2 2 2 0 Tripartite Tc toxins repeat Mucin PF01456.17 EIM80704.1 - 0.011 15.7 4.1 0.12 12.4 0.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein TMEM132D_C PF15706.5 EIM80704.1 - 0.037 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term WBP-1 PF11669.8 EIM80704.1 - 0.11 13.2 0.1 0.87 10.2 0.0 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 DRIM PF07539.12 EIM80705.1 - 3e-183 610.5 6.3 3e-183 610.5 6.3 3.3 3 1 0 3 3 3 2 Down-regulated in metastasis RICTOR_N PF14664.6 EIM80705.1 - 0.0085 15.1 0.7 2.9 6.8 0.0 3.1 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RIX1 PF08167.12 EIM80705.1 - 0.037 13.8 1.4 1.2 8.8 0.2 3.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis PRD PF00874.20 EIM80705.1 - 0.041 14.2 0.1 5 7.5 0.0 2.6 2 0 0 2 2 2 0 PRD domain UTP15_C PF09384.10 EIM80705.1 - 0.99 9.1 4.5 1.8 8.2 0.3 3.4 3 0 0 3 3 3 0 UTP15 C terminal HEAT_EZ PF13513.6 EIM80705.1 - 2.8 8.6 14.1 21 5.8 0.1 7.4 7 0 0 7 7 7 0 HEAT-like repeat CTK3 PF12243.8 EIM80706.1 - 3.8e-38 130.3 0.0 5.9e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EIM80706.1 - 2e-24 85.5 4.9 4.1e-24 84.5 4.9 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus P66_CC PF16563.5 EIM80706.1 - 0.13 11.9 0.4 0.13 11.9 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Gcn1_N PF12074.8 EIM80707.1 - 4.5e-84 282.8 3.5 8.4e-84 281.9 0.5 3.0 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EIM80707.1 - 4.5e-30 101.1 15.2 0.17 12.2 0.0 18.9 21 0 0 21 21 20 7 HEAT repeat HEAT_EZ PF13513.6 EIM80707.1 - 9.7e-29 99.4 19.8 0.00064 20.2 0.0 16.0 13 3 3 16 16 16 6 HEAT-like repeat HEAT_2 PF13646.6 EIM80707.1 - 1.1e-24 86.7 24.3 4e-06 27.1 0.1 13.0 10 2 2 12 12 12 7 HEAT repeats CLASP_N PF12348.8 EIM80707.1 - 4.1e-15 56.0 0.0 0.00057 19.5 0.0 6.7 4 1 1 7 7 7 3 CLASP N terminal Cnd1 PF12717.7 EIM80707.1 - 9.8e-12 45.2 0.0 2 8.4 0.0 8.9 7 2 2 9 9 9 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EIM80707.1 - 1.6e-05 25.4 0.0 4.7 7.9 0.0 6.2 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EIM80707.1 - 0.00012 20.8 6.6 2.1 6.8 0.0 6.8 7 2 1 8 8 8 1 Adaptin N terminal region Tti2 PF10521.9 EIM80707.1 - 0.00072 19.2 0.0 0.18 11.3 0.0 4.6 5 0 0 5 5 5 1 Tti2 family IFRD PF05004.13 EIM80707.1 - 0.00088 18.5 2.1 0.28 10.2 0.0 5.2 5 1 0 5 5 5 1 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 EIM80707.1 - 0.0059 15.3 2.7 4.7 5.8 0.0 5.0 5 1 0 5 5 5 1 Proteasome stabiliser Urb2 PF10441.9 EIM80707.1 - 0.11 12.5 4.5 2.5 8.0 2.2 3.5 2 1 0 2 2 2 0 Urb2/Npa2 family DUF3437 PF11919.8 EIM80707.1 - 0.15 12.0 0.4 17 5.4 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) DUF2267 PF10025.9 EIM80707.1 - 0.2 12.0 4.6 2.7 8.3 0.2 4.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) polyprenyl_synt PF00348.17 EIM80708.1 - 5.9e-61 205.8 0.0 8.7e-60 201.9 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase PHM7_cyt PF14703.6 EIM80708.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DZR PF12773.7 EIM80709.1 - 6.5 6.9 11.8 6.9 6.8 8.9 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF5106 PF17127.4 EIM80711.1 - 0.06 13.6 0.7 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) zf-MYND PF01753.18 EIM80713.1 - 2e-07 31.0 10.0 4.1e-07 30.0 10.0 1.5 1 0 0 1 1 1 1 MYND finger preSET_CXC PF18264.1 EIM80713.1 - 0.045 14.2 0.6 0.045 14.2 0.6 3.1 3 0 0 3 3 3 0 CXC domain Hydin_ADK PF17213.3 EIM80715.1 - 1.7 8.9 5.2 13 6.0 0.7 3.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain HNH_2 PF13391.6 EIM80720.1 - 0.024 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease HNH_2 PF13391.6 EIM80721.1 - 0.027 14.6 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease IATP PF04568.12 EIM80721.1 - 0.42 11.1 3.4 0.48 10.9 2.3 1.7 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP HNH_2 PF13391.6 EIM80722.1 - 0.00018 21.6 0.0 0.00047 20.2 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 EIM80723.1 - 0.0003 20.9 0.0 0.00081 19.5 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Cyclase PF04199.13 EIM80724.1 - 1.1e-30 106.6 0.0 1.4e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_31 PF01055.26 EIM80725.1 - 1.1e-136 456.6 7.7 1.4e-136 456.2 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EIM80725.1 - 3.2e-19 69.0 0.7 1.4e-18 67.0 0.1 2.5 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EIM80725.1 - 8.5e-06 26.0 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) HNH_2 PF13391.6 EIM80726.1 - 0.0071 16.5 0.2 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease HNH_2 PF13391.6 EIM80727.1 - 0.12 12.6 0.0 0.73 10.0 0.0 2.3 2 1 0 2 2 2 0 HNH endonuclease GATase_5 PF13507.6 EIM80728.1 - 4.6e-93 311.1 0.0 7.3e-93 310.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EIM80728.1 - 3.2e-40 137.8 2.9 6.5e-26 91.3 1.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EIM80728.1 - 1.8e-30 105.2 0.0 4.8e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EIM80728.1 - 1.7e-22 79.7 0.0 3.7e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain HNH_2 PF13391.6 EIM80728.1 - 0.00028 21.0 0.1 0.00059 19.9 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease AIRS PF00586.24 EIM80728.1 - 0.15 12.8 0.1 1.2 9.9 0.0 2.5 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain HNH_2 PF13391.6 EIM80729.1 - 0.014 15.6 0.1 0.04 14.1 0.1 1.9 1 1 0 1 1 1 0 HNH endonuclease E2R135 PF11570.8 EIM80729.1 - 0.022 15.1 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Gal_mutarotas_2 PF13802.6 EIM80729.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Galactose mutarotase-like 3HCDH_N PF02737.18 EIM80730.1 - 9.5e-50 169.0 0.6 6.4e-49 166.3 0.6 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EIM80730.1 - 6.9e-32 109.9 0.0 1.7e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EIM80730.1 - 0.039 14.1 0.4 0.14 12.3 0.4 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_RFF PF18321.1 EIM80730.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain NAD_binding_10 PF13460.6 EIM80731.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM80731.1 - 0.077 12.4 0.0 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EIM80731.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Peptidase_S8 PF00082.22 EIM80732.1 - 9.3e-33 113.7 10.5 1.6e-32 113.0 10.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EIM80732.1 - 2.1e-13 50.7 0.0 3.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DEAD PF00270.29 EIM80733.1 - 9.1e-16 58.1 0.0 1.9e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM80733.1 - 6.5e-11 42.5 0.0 2e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM80733.1 - 2.9e-05 24.4 0.0 9e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM80734.1 - 9.5e-44 149.2 0.3 1.6e-43 148.5 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM80734.1 - 6.5e-19 68.3 0.0 5.9e-18 65.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-MYND PF01753.18 EIM80734.1 - 9.1e-08 32.1 12.1 1.8e-07 31.2 12.1 1.5 1 0 0 1 1 1 1 MYND finger ResIII PF04851.15 EIM80734.1 - 8.2e-07 29.2 0.1 1.4e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EIM80734.1 - 0.019 14.2 0.0 0.052 12.7 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase HNH_2 PF13391.6 EIM80735.1 - 0.0041 17.2 0.2 0.0094 16.1 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 EIM80736.1 - 0.0017 18.5 0.3 0.0048 17.0 0.3 1.7 1 0 0 1 1 1 1 HNH endonuclease Sulfate_transp PF00916.20 EIM80739.1 - 4.2e-86 289.1 13.4 4.2e-86 289.1 13.4 1.7 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 EIM80739.1 - 6.9e-18 64.4 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EIM80739.1 - 0.00026 21.3 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 STAS domain WD40 PF00400.32 EIM80740.1 - 0.0094 16.8 12.1 27 5.8 0.0 6.9 7 0 0 7 7 7 1 WD domain, G-beta repeat ArsB PF02040.15 EIM80741.1 - 2.4e-13 50.2 14.9 8.7e-10 38.5 4.1 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 EIM80741.1 - 5.1e-10 39.0 9.4 5.1e-10 39.0 9.4 2.0 2 1 1 3 3 3 2 Citrate transporter Pkinase PF00069.25 EIM80742.1 - 1.5e-65 221.2 0.0 1.8e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM80742.1 - 1.3e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MTCP1 PF08991.10 EIM80743.1 - 9.8e-22 77.0 5.5 1.1e-21 76.8 5.5 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EIM80743.1 - 0.0074 16.4 3.7 0.0074 16.4 3.7 1.7 1 1 1 2 2 2 1 CHCH domain Cmc1 PF08583.10 EIM80743.1 - 3.6 7.7 9.0 0.43 10.6 1.7 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like SNF2_N PF00176.23 EIM80744.1 - 1.3e-63 214.8 0.2 2.3e-63 214.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM80744.1 - 1.5e-17 63.9 0.0 6.3e-16 58.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM80744.1 - 6.3e-08 32.8 0.0 3.1e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIM80744.1 - 0.00078 19.3 0.0 0.0029 17.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Transcrip_reg PF01709.20 EIM80745.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator DAAD PF18752.1 EIM80745.1 - 0.13 12.1 0.0 0.98 9.2 0.0 2.4 3 0 0 3 3 3 0 Dictyosteliid AID/APOBEC-like Deaminase Mito_carr PF00153.27 EIM80747.1 - 1.1e-63 211.2 1.0 5.4e-20 71.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 EIM80748.1 - 1.2e-19 70.5 0.0 2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EIM80748.1 - 1.2e-13 51.5 0.1 6.6e-06 26.4 0.0 4.2 4 2 0 4 4 4 2 Calpain large subunit, domain III MIT PF04212.18 EIM80748.1 - 1e-07 31.9 0.3 1.6e-07 31.3 0.3 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DnaJ PF00226.31 EIM80749.1 - 2.7e-13 49.8 0.0 4.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ATF7IP_BD PF16788.5 EIM80749.1 - 0.039 14.1 0.2 0.064 13.4 0.2 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain Cortex-I_coil PF09304.10 EIM80749.1 - 0.54 10.5 2.7 0.97 9.7 2.7 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil p450 PF00067.22 EIM80751.1 - 7.9e-51 173.2 0.0 9.3e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_8 PF13855.6 EIM80752.1 - 0.0023 17.6 1.9 0.013 15.3 1.9 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRRNT_2 PF08263.12 EIM80752.1 - 0.0043 17.3 2.0 0.0043 17.3 2.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 EIM80752.1 - 0.016 15.6 1.6 0.076 13.5 1.6 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) CbtA PF09490.10 EIM80752.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Pantoate_transf PF02548.15 EIM80754.1 - 3.6e-97 324.8 0.1 2.3e-89 299.3 0.0 2.0 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EIM80754.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Rit1_C PF17184.4 EIM80755.1 - 4.9e-93 311.5 0.0 6.3e-93 311.2 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EIM80755.1 - 9.4e-30 103.1 0.0 2.2e-29 101.9 0.0 1.6 2 0 0 2 2 2 1 Rit1 DUSP-like domain ER_lumen_recept PF00810.18 EIM80756.1 - 9.7e-57 191.9 4.9 1.5e-56 191.4 4.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EIM80756.1 - 4.2e-05 23.2 5.4 0.32 10.8 0.0 4.0 2 1 2 4 4 4 3 PQ loop repeat Lectin_leg-like PF03388.13 EIM80757.1 - 3.7e-68 229.3 0.4 4.8e-68 228.9 0.4 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 EIM80757.1 - 0.00021 20.9 0.1 0.0028 17.2 0.1 2.1 1 1 0 1 1 1 1 Legume lectin domain DUF4203 PF13886.6 EIM80758.1 - 1.5e-15 57.5 26.8 2e-15 57.0 26.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3925 PF13063.6 EIM80758.1 - 7.8 6.8 10.4 2.2 8.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) Dimer_Tnp_hAT PF05699.14 EIM80760.1 - 2.9e-06 27.0 0.2 0.0066 16.2 0.0 3.0 2 1 1 3 3 3 2 hAT family C-terminal dimerisation region FSH1 PF03959.13 EIM80761.1 - 3.9e-56 190.1 0.0 4.8e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EIM80761.1 - 5.7e-05 23.8 0.1 0.00026 21.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EIM80761.1 - 0.001 18.9 0.1 0.08 12.7 0.2 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EIM80761.1 - 0.04 13.2 0.0 0.4 9.9 0.0 2.3 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DLH PF01738.18 EIM80761.1 - 0.18 11.3 0.0 0.93 9.0 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family HEAT_EZ PF13513.6 EIM80762.1 - 8.5e-29 99.6 16.3 1.3e-15 57.5 0.0 10.4 10 1 1 11 11 11 4 HEAT-like repeat HEAT PF02985.22 EIM80762.1 - 6.7e-22 75.7 14.5 0.00028 20.9 0.0 10.2 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EIM80762.1 - 3.2e-16 59.5 0.5 0.00012 22.4 0.0 7.3 5 3 3 8 8 8 4 HEAT repeats Cnd1 PF12717.7 EIM80762.1 - 7.4e-08 32.6 0.1 0.66 10.0 0.0 5.4 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 EIM80762.1 - 8.8e-08 32.0 0.6 0.002 18.0 0.0 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3437) Vac14_Fab1_bd PF12755.7 EIM80762.1 - 1.3e-07 32.1 0.0 0.076 13.6 0.1 4.4 3 2 1 4 4 4 3 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 EIM80762.1 - 2e-05 24.8 0.3 0.12 12.7 0.1 4.0 4 0 0 4 4 3 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 EIM80762.1 - 0.00026 19.7 0.6 0.12 10.9 0.1 3.6 4 0 0 4 4 4 1 Adaptin N terminal region IBN_N PF03810.19 EIM80762.1 - 0.0025 17.7 0.0 0.0098 15.8 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Arm PF00514.23 EIM80762.1 - 0.0072 16.3 0.0 9.4 6.4 0.0 4.8 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EIM80762.1 - 0.016 15.4 0.3 0.079 13.1 0.0 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EIM80762.1 - 0.028 13.6 0.1 2.8 7.1 0.0 3.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Tti2 PF10521.9 EIM80762.1 - 0.041 13.4 0.2 7.7 6.0 0.0 3.0 2 1 1 3 3 3 0 Tti2 family Ecm29 PF13001.7 EIM80762.1 - 0.047 12.4 0.1 2.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Proteasome stabiliser TAF6_C PF07571.13 EIM80762.1 - 0.18 12.1 0.0 11 6.4 0.0 2.9 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain p450 PF00067.22 EIM80763.1 - 1.9e-52 178.5 0.1 2.2e-52 178.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kri1_C PF12936.7 EIM80764.1 - 2.5e-23 82.0 0.7 2.5e-23 82.0 0.7 5.8 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 EIM80764.1 - 1.4e-22 80.2 8.5 1.4e-22 80.2 8.5 7.3 8 1 0 8 8 8 2 KRI1-like family CSRNP_N PF16019.5 EIM80764.1 - 0.00014 21.9 1.6 0.00014 21.9 1.6 5.2 5 1 0 6 6 6 1 Cysteine/serine-rich nuclear protein N-terminus Dynamin_N PF00350.23 EIM80765.1 - 1.8e-13 50.9 0.0 2.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EIM80765.1 - 7.3e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EIM80765.1 - 0.074 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Calsequestrin PF01216.17 EIM80765.1 - 0.095 11.7 0.0 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 Calsequestrin Dynamin_M PF01031.20 EIM80766.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EIM80767.1 - 2.4e-09 37.2 0.2 3.8e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Dynamin GTPase effector domain DnaB_bind PF10410.9 EIM80767.1 - 0.061 13.5 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Dynamin_M PF01031.20 EIM80768.1 - 1.5e-32 113.0 0.0 3.4e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EIM80768.1 - 3.4e-28 98.8 0.0 1e-27 97.2 0.0 1.8 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EIM80768.1 - 4.3e-05 23.6 0.0 0.00032 20.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM80768.1 - 0.0072 16.7 0.1 0.36 11.2 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Orthopox_F14 PF06076.12 EIM80768.1 - 0.011 16.0 0.3 0.31 11.3 0.1 2.5 2 0 0 2 2 2 0 Orthopoxvirus F14 protein DUF2150 PF09920.9 EIM80768.1 - 0.08 12.9 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) GshA PF08886.11 EIM80768.1 - 0.16 10.5 0.0 0.8 8.2 0.0 1.9 2 0 0 2 2 2 0 Glutamate-cysteine ligase PBP1_TM PF14812.6 EIM80771.1 - 0.004 17.5 2.1 0.004 17.5 2.1 1.8 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF913 PF06025.12 EIM80771.1 - 0.015 14.3 0.9 0.018 14.0 0.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCDC106 PF15794.5 EIM80771.1 - 0.39 10.4 5.1 0.51 10.0 5.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 EIM80771.1 - 2.7 6.2 7.3 2.7 6.2 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 EIM80771.1 - 3.1 6.5 9.2 4.3 6.1 9.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Tfb4 PF03850.14 EIM80772.1 - 0.21 11.0 0.4 0.29 10.6 0.4 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 CDK2AP PF09806.9 EIM80772.1 - 0.61 10.1 7.8 0.33 11.0 3.4 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein adh_short_C2 PF13561.6 EIM80773.1 - 5.6e-48 163.5 0.0 6.6e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM80773.1 - 5.3e-33 114.1 0.1 6.4e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM80773.1 - 1.9e-07 31.2 0.1 2.7e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Dynamin_N PF00350.23 EIM80775.1 - 2.6e-28 99.2 0.0 5.1e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EIM80775.1 - 1.4e-24 86.8 0.0 6.8e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EIM80775.1 - 1.2e-11 44.6 0.6 7.6e-11 42.0 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EIM80775.1 - 8.1e-06 25.9 0.0 8.1e-05 22.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM80775.1 - 0.011 16.2 0.4 0.17 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EIM80775.1 - 0.017 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EIM80775.1 - 0.049 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EIM80775.1 - 0.056 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_15 PF13175.6 EIM80775.1 - 0.08 12.6 0.5 0.33 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EIM80775.1 - 5.1 7.5 7.0 1.5 9.3 0.1 2.8 3 0 0 3 3 3 0 AAA domain Ceramidase_alk PF04734.13 EIM80776.1 - 6.5e-208 691.5 0.2 7.7e-208 691.2 0.2 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EIM80776.1 - 2.9e-56 189.9 0.4 5.1e-56 189.1 0.4 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF2828 PF11443.8 EIM80777.1 - 9.5e-221 734.3 0.2 2.2e-220 733.0 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) zf-MYND PF01753.18 EIM80778.1 - 0.0017 18.4 9.6 0.0032 17.5 9.6 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EIM80778.1 - 2.8 7.9 7.8 5.1 7.1 7.8 1.4 1 0 0 1 1 1 0 HIT zinc finger ORC6 PF05460.13 EIM80780.1 - 1.9 7.7 5.9 0.43 9.8 0.7 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) MULE PF10551.9 EIM80782.1 - 3.9e-10 40.0 0.0 7.2e-09 36.0 0.0 2.6 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EIM80782.1 - 0.00019 21.0 0.6 0.00047 19.8 0.6 1.7 1 0 0 1 1 1 1 SWIM zinc finger SET PF00856.28 EIM80783.1 - 0.0058 17.0 0.1 0.013 15.9 0.1 1.7 1 1 0 1 1 1 1 SET domain Ribosomal_L17 PF01196.19 EIM80783.1 - 0.18 12.7 0.0 0.39 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L17 zf-MYND PF01753.18 EIM80784.1 - 4.8e-06 26.6 12.6 9.4e-06 25.6 12.6 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM80784.1 - 1.2 9.4 6.0 2.5 8.5 6.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Lipase_GDSL PF00657.22 EIM80785.1 - 0.00082 19.4 0.1 0.0015 18.5 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIM80785.1 - 0.011 16.2 2.8 0.021 15.2 2.8 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4908 PF16252.5 EIM80785.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) NAD_binding_5 PF07994.12 EIM80786.1 - 5.8e-138 459.7 0.0 2.1e-137 457.8 0.0 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EIM80786.1 - 5.7e-44 148.8 0.1 9.9e-44 148.1 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase p450 PF00067.22 EIM80787.1 - 8.3e-64 216.0 0.0 1e-63 215.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM80788.1 - 5.9e-73 246.2 0.0 6.7e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sen15 PF09631.10 EIM80789.1 - 2.6e-20 72.6 0.0 3.5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein NIF PF03031.18 EIM80790.1 - 3.7e-36 124.2 0.0 5e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2076 PF09849.9 EIM80790.1 - 1.1 9.2 12.2 0.15 12.1 6.6 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2569 PF10754.9 EIM80791.1 - 0.00079 19.9 18.3 0.089 13.2 6.2 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF2569) F-box-like PF12937.7 EIM80792.1 - 2e-05 24.4 0.8 6.2e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM80792.1 - 0.0082 16.0 0.1 0.02 14.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_31 PF01055.26 EIM80793.1 - 5.4e-41 141.2 3.5 8e-41 140.6 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EIM80793.1 - 0.012 15.9 2.2 0.083 13.2 0.3 3.1 3 1 0 3 3 3 0 Galactose mutarotase-like Cpn60_TCP1 PF00118.24 EIM80796.1 - 6.7e-143 476.9 2.2 7.5e-143 476.7 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 EIM80796.1 - 0.0057 17.0 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor F-box-like PF12937.7 EIM80797.1 - 0.00064 19.6 0.9 0.0018 18.1 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM80801.1 - 0.007 16.2 0.7 0.007 16.2 0.7 2.4 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EIM80801.1 - 0.1 13.0 1.8 11 6.6 0.1 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) KR PF08659.10 EIM80802.1 - 0.00036 20.5 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EIM80802.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_28 PF00295.17 EIM80803.1 - 2e-60 204.5 22.0 2.7e-60 204.1 22.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EIM80803.1 - 7.9e-11 42.1 23.7 2.2e-08 34.1 9.3 3.6 2 1 1 3 3 3 2 Right handed beta helix region DUF1565 PF07602.11 EIM80803.1 - 3.8e-05 23.1 3.0 3.8e-05 23.1 3.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1565) TOBE_2 PF08402.10 EIM80803.1 - 0.019 15.1 0.2 2.3 8.5 0.0 3.5 3 0 0 3 3 3 0 TOBE domain ATP-grasp PF02222.22 EIM80804.1 - 0.0095 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RVT_N PF13655.6 EIM80804.1 - 0.62 10.4 3.3 0.3 11.4 0.6 1.9 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase TMEM154 PF15102.6 EIM80805.1 - 0.00085 19.2 0.0 0.00085 19.2 0.0 2.4 3 0 0 3 3 3 1 TMEM154 protein family Protocadherin PF08374.11 EIM80805.1 - 0.03 14.3 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 0 Protocadherin Mid2 PF04478.12 EIM80805.1 - 0.035 13.9 5.0 0.067 13.0 5.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.16 EIM80805.1 - 0.089 11.5 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mito_carr PF00153.27 EIM80806.1 - 1.4e-59 198.0 4.0 2.8e-23 81.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2835 PF11197.8 EIM80806.1 - 0.034 14.0 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) Colicin_V PF02674.16 EIM80806.1 - 0.41 10.6 2.4 17 5.4 0.0 2.7 3 0 0 3 3 3 0 Colicin V production protein DUF4470 PF14737.6 EIM80807.1 - 3.1e-20 72.2 0.1 5.3e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EIM80807.1 - 0.00014 21.9 8.0 0.00026 21.0 8.0 1.4 1 0 0 1 1 1 1 MYND finger CHAT PF12770.7 EIM80808.1 - 7.4e-36 124.0 0.0 1.4e-35 123.1 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_19 PF14559.6 EIM80808.1 - 0.065 13.8 0.8 35 5.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RhoGAP PF00620.27 EIM80809.1 - 6.5e-41 139.7 0.0 1.6e-40 138.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 EIM80809.1 - 3.2e-09 37.2 0.0 8.9e-08 32.5 0.0 2.6 2 0 0 2 2 2 1 RasGEF domain PH_9 PF15410.6 EIM80809.1 - 1.2e-06 28.9 0.0 1.6e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EIM80809.1 - 6.9e-06 26.5 0.0 0.0044 17.5 0.0 2.6 2 0 0 2 2 2 2 PH domain RasGEF_N PF00618.20 EIM80809.1 - 0.00022 21.4 0.1 0.0014 18.9 0.0 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif p450 PF00067.22 EIM80810.1 - 5.4e-64 216.6 0.0 6.8e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM80811.1 - 1.8e-09 36.9 0.0 2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C12 PF01088.21 EIM80812.1 - 1.9e-44 151.9 0.0 2.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sugarporin_N PF11471.8 EIM80812.1 - 0.2 11.6 0.6 0.67 10.0 0.2 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension F-box-like PF12937.7 EIM80813.1 - 0.00012 21.8 0.2 0.0046 16.8 0.2 2.5 2 0 0 2 2 2 2 F-box-like 2OG-FeII_Oxy_3 PF13640.6 EIM80814.1 - 2.4e-07 31.6 0.0 4.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Bromodomain PF00439.25 EIM80816.1 - 4.7e-22 77.9 1.3 1.3e-21 76.5 0.9 1.9 1 1 1 2 2 2 1 Bromodomain Bromo_TP PF07524.13 EIM80816.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated WD40 PF00400.32 EIM80818.1 - 1.3e-17 63.9 13.7 8.3e-05 23.3 0.0 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM80818.1 - 1.3e-14 54.3 1.2 7.6e-07 29.3 0.1 4.4 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM80818.1 - 0.00011 22.1 0.1 0.019 14.9 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A GHMP_kinases_N PF00288.26 EIM80818.1 - 0.028 14.6 1.2 0.38 11.0 1.0 2.5 2 0 0 2 2 2 0 GHMP kinases N terminal domain Ge1_WD40 PF16529.5 EIM80818.1 - 0.11 11.5 0.0 0.65 8.9 0.0 2.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPIP1 PF15338.6 EIM80819.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 2OG-FeII_Oxy_3 PF13640.6 EIM80820.1 - 9.7e-09 36.0 0.0 3.3e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_6 PF13405.6 EIM80821.1 - 1.7e-22 77.4 1.1 3.4e-07 29.7 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EIM80821.1 - 9.9e-22 74.8 1.7 2.6e-06 26.6 0.1 4.9 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EIM80821.1 - 5.7e-20 71.5 0.9 1.4e-08 35.0 0.3 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EIM80821.1 - 1.2e-16 59.4 1.1 0.00012 21.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EIM80821.1 - 7e-12 45.0 4.8 8.7e-07 28.7 0.0 4.5 3 3 1 4 4 4 2 EF-hand domain pair MukF_M PF17192.4 EIM80821.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 MukF middle domain PEP_mutase PF13714.6 EIM80822.1 - 1.7e-40 139.0 0.3 2e-40 138.7 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EIM80822.1 - 2.6e-18 65.8 0.2 3.4e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PARP PF00644.20 EIM80823.1 - 8.5e-13 48.3 2.1 1.7e-09 37.6 0.1 2.9 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PLATZ PF04640.14 EIM80823.1 - 7.6 7.2 10.1 0.3 11.8 1.8 2.5 2 1 1 3 3 3 0 PLATZ transcription factor F-box-like PF12937.7 EIM80824.1 - 3.7e-05 23.5 1.1 0.0001 22.1 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM80824.1 - 0.00011 22.0 0.6 0.0003 20.6 0.6 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EIM80824.1 - 0.14 12.0 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 F-box TUG-UBL1 PF11470.8 EIM80825.1 - 0.04 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain RBD PF02196.15 EIM80825.1 - 0.045 13.8 0.0 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Raf-like Ras-binding domain ABC_tran PF00005.27 EIM80826.1 - 1.7e-30 106.3 0.0 1.2e-15 58.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 EIM80826.1 - 6.1e-05 23.2 0.2 0.1 12.9 0.1 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EIM80826.1 - 8e-05 22.6 1.6 0.059 13.2 0.1 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Ploopntkinase1 PF18748.1 EIM80826.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_29 PF13555.6 EIM80826.1 - 0.04 13.7 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.19 EIM80826.1 - 0.073 12.5 0.0 0.21 11.0 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 EIM80826.1 - 0.11 10.0 0.1 0.16 9.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 EIM80826.1 - 0.13 10.9 0.1 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain V-SNARE_C PF12352.8 EIM80830.1 - 2.1e-16 60.0 0.3 2.1e-16 60.0 0.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EIM80830.1 - 3.4e-08 33.3 0.6 6.5e-07 29.2 0.0 2.4 2 1 0 2 2 2 1 Sec20 Wbp11 PF09429.10 EIM80830.1 - 0.013 15.9 3.6 1.9 9.0 3.8 2.5 2 0 0 2 2 2 0 WW domain binding protein 11 Plasmid_RAQPRD PF09686.10 EIM80830.1 - 0.025 14.8 2.3 0.11 12.8 1.0 2.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Phage_holin_2_3 PF16080.5 EIM80830.1 - 0.22 11.3 1.4 0.46 10.3 1.4 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 IFT20 PF14931.6 EIM80830.1 - 0.33 11.1 4.5 0.44 10.7 2.1 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Prefoldin_2 PF01920.20 EIM80830.1 - 0.57 10.2 6.3 0.96 9.4 3.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit ADIP PF11559.8 EIM80830.1 - 1.1 9.4 8.8 0.13 12.3 4.6 1.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Adaptin_binding PF10199.9 EIM80830.1 - 1.5 9.4 5.6 7.5 7.2 5.6 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF4554 PF15091.6 EIM80830.1 - 1.6 7.6 5.7 2.1 7.1 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Peptidase_M28 PF04389.17 EIM80831.1 - 3.1e-33 115.1 0.1 4.5e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EIM80831.1 - 0.0014 17.8 0.0 0.0037 16.3 0.0 1.6 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EIM80831.1 - 0.0059 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Phage_lysis PF03245.13 EIM80832.1 - 2 8.5 5.2 0.23 11.6 0.3 1.8 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein RRM_1 PF00076.22 EIM80833.1 - 7.2e-30 102.6 1.5 6.9e-09 35.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM80833.1 - 0.0017 18.1 0.0 2.9 7.8 0.0 3.7 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EIM80833.1 - 0.0025 17.8 3.5 0.49 10.5 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 EIM80833.1 - 0.021 14.4 0.0 0.13 11.8 0.0 2.3 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1631 PF07793.11 EIM80834.1 - 8.5 4.7 5.8 14 3.9 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) FCH PF00611.23 EIM80835.1 - 2.4e-15 56.6 0.1 7.6e-15 55.0 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EIM80835.1 - 7.1e-11 41.5 0.0 1.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM80835.1 - 1.4e-09 37.7 0.0 3.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIM80835.1 - 4.3e-07 29.5 0.0 1.7e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Metallophos PF00149.28 EIM80836.1 - 3.2e-14 53.9 2.9 4.1e-14 53.6 2.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EIM80836.1 - 0.0085 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain SNRNP27 PF08648.12 EIM80836.1 - 8.4 6.5 6.5 21 5.3 0.1 3.0 3 0 0 3 3 3 0 U4/U6.U5 small nuclear ribonucleoproteins Bac_rhodopsin PF01036.18 EIM80840.1 - 8.9e-38 130.1 18.2 1e-37 129.9 18.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2157 PF09925.9 EIM80840.1 - 0.14 12.0 13.0 0.056 13.2 9.2 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4956 PF16316.5 EIM80840.1 - 5.4 6.7 6.9 12 5.6 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Solute_trans_a PF03619.16 EIM80840.1 - 7.3 6.0 11.0 5.5 6.4 1.5 2.2 1 1 1 2 2 2 0 Organic solute transporter Ostalpha PAPA-1 PF04795.12 EIM80841.1 - 5.2e-18 65.6 6.5 5.2e-18 65.6 6.5 2.5 2 1 0 2 2 2 1 PAPA-1-like conserved region O-FucT PF10250.9 EIM80842.1 - 2e-06 27.8 0.0 5e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.7 EIM80845.1 - 1.1e-09 38.0 0.4 3e-09 36.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like zf-C2HC_2 PF13913.6 EIM80845.1 - 0.0041 17.0 0.1 0.0079 16.1 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type F-box PF00646.33 EIM80845.1 - 0.084 12.8 0.8 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 EIM80846.1 - 1.2e-13 51.5 0.0 6e-13 49.2 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM80846.1 - 3.1e-11 43.3 0.1 9.5e-07 29.0 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM80846.1 - 6.5e-10 38.4 0.1 0.0003 21.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EIM80846.1 - 1.9e-09 37.8 0.1 6.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EIM80846.1 - 4.3e-07 30.1 0.4 0.0072 16.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Cytomega_UL20A PF05984.12 EIM80846.1 - 0.19 12.0 1.3 0.46 10.8 1.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Cwf_Cwc_15 PF04889.12 EIM80848.1 - 1.1e-84 284.0 28.3 1.3e-84 283.8 28.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NTP_transf_8 PF12281.8 EIM80848.1 - 0.012 15.7 1.6 0.017 15.1 0.2 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase Nop14 PF04147.12 EIM80848.1 - 0.18 10.0 29.6 0.22 9.7 29.6 1.1 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.7 EIM80849.1 - 7.3e-10 38.6 3.0 3.4e-09 36.4 0.7 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM80849.1 - 0.0014 18.5 1.7 0.0039 17.0 0.3 2.5 2 1 0 2 2 2 1 F-box domain Cupin_2 PF07883.11 EIM80850.1 - 1.5e-07 31.0 0.0 2.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EIM80850.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Acetyltransf_7 PF13508.7 EIM80851.1 - 2.9e-06 27.6 0.0 7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM80851.1 - 0.00039 20.4 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM80851.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80851.1 - 0.003 17.8 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PseudoU_synth_2 PF00849.22 EIM80852.1 - 1e-27 97.2 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase ABC_tran PF00005.27 EIM80853.1 - 1.7e-46 158.1 0.1 1.4e-22 80.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EIM80853.1 - 4.3e-44 150.5 33.8 8e-30 103.8 14.2 3.5 3 1 0 3 3 2 2 ABC-2 type transporter SMC_N PF02463.19 EIM80853.1 - 3e-10 39.9 0.6 5.6e-05 22.7 0.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EIM80853.1 - 6.6e-10 39.3 0.9 0.15 11.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EIM80853.1 - 2.9e-07 30.5 1.4 0.005 16.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EIM80853.1 - 1.1e-05 25.1 3.8 0.029 14.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EIM80853.1 - 4.4e-05 23.9 0.2 0.13 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EIM80853.1 - 5.2e-05 22.9 0.1 0.51 9.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EIM80853.1 - 6.4e-05 23.5 4.0 0.031 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EIM80853.1 - 0.00011 22.5 0.5 0.3 11.4 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EIM80853.1 - 0.00061 19.6 0.3 0.33 10.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain PDR_CDR PF06422.12 EIM80853.1 - 0.00069 19.5 0.4 0.0099 15.8 0.4 2.5 2 0 0 2 2 2 1 CDR ABC transporter AAA_28 PF13521.6 EIM80853.1 - 0.00073 19.8 0.6 0.07 13.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIM80853.1 - 0.0008 19.8 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 EIM80853.1 - 0.0012 18.6 0.0 3.7 7.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 EIM80853.1 - 0.002 18.7 0.1 2 8.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EIM80853.1 - 0.0028 17.6 0.0 1.9 8.4 0.0 3.0 3 0 0 3 3 3 1 NACHT domain T2SSE PF00437.20 EIM80853.1 - 0.0034 16.5 0.8 0.89 8.6 0.3 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.14 EIM80853.1 - 0.004 17.2 0.4 4.1 7.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EIM80853.1 - 0.0058 16.7 0.6 2.2 8.4 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EIM80853.1 - 0.009 15.8 0.3 1.6 8.4 0.1 2.7 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 EIM80853.1 - 0.014 14.7 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 EIM80853.1 - 0.023 13.9 0.0 5.4 6.2 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 EIM80853.1 - 0.031 14.6 0.1 0.87 9.9 0.1 2.8 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 EIM80853.1 - 0.042 13.8 0.2 1.9 8.4 0.1 3.2 4 0 0 4 4 3 0 NTPase cobW PF02492.19 EIM80853.1 - 0.042 13.4 0.8 5 6.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EIM80853.1 - 0.063 13.5 0.0 16 5.8 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EIM80853.1 - 0.064 13.2 0.0 8.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 EIM80853.1 - 0.1 11.9 3.2 4.9 6.4 0.3 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EIM80853.1 - 0.11 12.1 1.3 16 5.2 0.2 2.6 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 EIM80853.1 - 0.14 12.5 0.2 6.1 7.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 EIM80853.1 - 0.22 11.2 0.5 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC2_membrane_3 PF12698.7 EIM80853.1 - 0.27 10.3 27.1 0.14 11.2 13.2 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Cytidylate_kin PF02224.18 EIM80853.1 - 0.8 9.4 3.4 3.5 7.3 0.1 3.0 3 0 0 3 3 3 0 Cytidylate kinase Pox_A32 PF04665.12 EIM80853.1 - 1.3 8.4 5.0 1.2 8.5 0.2 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein ABC2_membrane_2 PF12679.7 EIM80853.1 - 2.1 7.5 21.9 0.022 14.1 8.4 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF935 PF06074.12 EIM80854.1 - 0.26 10.0 1.3 11 4.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF935) zf-MYND PF01753.18 EIM80855.1 - 0.00032 20.7 16.8 0.043 13.9 3.0 2.6 2 0 0 2 2 2 2 MYND finger Aminotran_5 PF00266.19 EIM80857.1 - 2.1e-21 76.3 0.0 5.2e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Uso1_p115_head PF04869.14 EIM80858.1 - 1.5e-37 129.4 0.0 2.8e-33 115.4 0.0 2.9 3 0 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EIM80858.1 - 1.6e-14 54.3 27.1 1.6e-14 54.3 27.1 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 EIM80858.1 - 0.0055 16.9 11.1 0.0055 16.9 11.1 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EIM80858.1 - 0.14 11.6 12.5 0.21 11.0 12.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EIM80858.1 - 0.3 10.4 5.0 0.51 9.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm2_III-A PF03750.13 EIM80858.1 - 0.36 11.7 2.4 0.71 10.7 2.4 1.4 1 0 0 1 1 1 0 Csm2 Type III-A TEX13 PF15186.6 EIM80858.1 - 0.36 10.5 6.5 0.78 9.4 6.5 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family OmpH PF03938.14 EIM80858.1 - 0.92 9.8 9.5 2 8.8 9.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MIF4G_like_2 PF09090.11 EIM80858.1 - 1.6 8.1 5.6 0.72 9.3 3.3 1.5 2 0 0 2 2 2 0 MIF4G like E1-E2_ATPase PF00122.20 EIM80859.1 - 9.8e-47 158.8 0.0 9.8e-47 158.8 0.0 2.6 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EIM80859.1 - 2.2e-37 128.5 1.1 4.9e-37 127.4 1.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EIM80859.1 - 1.1e-19 71.5 0.1 1.2e-08 35.5 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIM80859.1 - 3.1e-10 39.6 0.0 6.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EIM80859.1 - 3.5e-09 36.6 0.0 1.1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EIM80859.1 - 4.8e-05 23.2 0.7 0.0012 18.6 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 EIM80859.1 - 0.0022 17.9 0.1 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC p450 PF00067.22 EIM80862.1 - 1.6e-71 241.5 0.0 4.8e-71 239.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.15 EIM80866.1 - 1.2e-14 53.9 0.2 1.2e-12 47.3 0.0 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 EIM80866.1 - 9.3e-10 38.8 0.2 1.4e-05 25.1 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EIM80866.1 - 4.5e-06 26.7 7.3 4.5e-06 26.7 7.3 2.6 1 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EIM80866.1 - 0.00012 21.6 0.1 0.00022 20.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EIM80866.1 - 0.00025 20.9 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Metallophos PF00149.28 EIM80868.1 - 1.5e-30 107.2 0.0 2.2e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EIM80868.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EIM80868.1 - 0.16 12.4 0.4 0.33 11.4 0.4 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Hydrolase_4 PF12146.8 EIM80869.1 - 6.3e-05 22.4 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM80869.1 - 0.00012 22.8 6.6 0.00027 21.6 6.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EIM80869.1 - 0.00014 22.1 0.8 0.00044 20.4 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 EIM80869.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 EIM80869.1 - 0.0022 17.6 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EIM80869.1 - 0.0051 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA_11 PF13086.6 EIM80869.1 - 0.36 10.6 6.8 0.63 9.8 6.8 1.3 1 0 0 1 1 1 0 AAA domain Med19 PF10278.9 EIM80869.1 - 1.3 8.9 13.0 2.8 7.8 13.0 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Borrelia_P83 PF05262.11 EIM80869.1 - 1.5 7.2 13.9 2.5 6.5 13.9 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4193 PF13834.6 EIM80869.1 - 2 8.9 0.0 2 8.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4193) NARP1 PF12569.8 EIM80869.1 - 3.1 6.6 14.1 4.6 6.0 14.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Abhydrolase_1 PF00561.20 EIM80870.1 - 1.8e-09 37.6 0.4 1.8e-08 34.3 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM80870.1 - 4.2e-08 34.1 0.0 5.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM80870.1 - 1.1e-06 28.1 0.1 2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Acetyltransf_3 PF13302.7 EIM80871.1 - 2.1e-16 60.8 0.1 2.6e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80871.1 - 7.7e-11 42.3 0.0 9.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM80871.1 - 1.7e-09 38.0 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EIM80871.1 - 1.3e-06 28.6 0.0 1.7e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM80871.1 - 4.2e-05 23.4 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EIM80871.1 - 5.1e-05 23.2 0.0 6.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EIM80871.1 - 0.00028 20.6 0.0 0.00035 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BRI3BP PF14965.6 EIM80872.1 - 6.2 6.3 10.6 0.44 10.0 0.5 2.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF3328 PF11807.8 EIM80874.1 - 2.2e-20 73.4 0.4 2.8e-20 73.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Abhydrolase_1 PF00561.20 EIM80875.1 - 4.5e-15 56.0 0.0 5.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM80875.1 - 3.9e-09 36.1 0.0 8e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM80875.1 - 3.6e-05 24.5 0.0 4.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pro-kuma_activ PF09286.11 EIM80876.1 - 3.3e-37 128.0 0.0 5.9e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain IKI3 PF04762.12 EIM80878.1 - 7.5e-221 735.8 0.0 1.1e-165 553.2 0.0 2.6 1 1 1 2 2 2 2 IKI3 family Clathrin PF00637.20 EIM80878.1 - 0.019 14.8 2.5 2.6 7.9 0.0 3.4 1 1 2 3 3 3 0 Region in Clathrin and VPS Efg1 PF10153.9 EIM80879.1 - 7.9e-36 122.9 8.8 7.9e-36 122.9 8.8 2.3 4 0 0 4 4 4 1 rRNA-processing protein Efg1 Sigma70_r3 PF04539.16 EIM80880.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 SPOB_ab PF14682.6 EIM80881.1 - 0.034 14.2 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Tricho_coat PF05892.11 EIM80882.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Trichovirus coat protein FAD_binding_4 PF01565.23 EIM80884.1 - 3.6e-11 42.9 1.5 0.00032 20.5 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.12 EIM80884.1 - 3.1e-06 27.2 0.0 6.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EIM80884.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.14 EIM80884.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase SprT-like PF10263.9 EIM80885.1 - 9.3e-30 102.8 0.0 1.5e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EIM80885.1 - 0.0053 16.6 0.6 0.0093 15.9 0.6 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EIM80885.1 - 0.04 14.0 0.5 0.083 13.0 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Aldo_ket_red PF00248.21 EIM80886.1 - 1.9e-49 168.5 0.1 1.2e-48 165.8 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.6 EIM80888.1 - 6.8e-07 29.5 0.0 1.6e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM80888.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Tudor_2 PF18104.1 EIM80888.1 - 0.25 11.1 1.3 3.9 7.3 0.4 2.4 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain RhoGEF PF00621.20 EIM80889.1 - 2e-26 93.4 0.0 7.2e-24 85.0 0.0 2.5 2 0 0 2 2 2 2 RhoGEF domain LRR_4 PF12799.7 EIM80892.1 - 0.06 13.8 4.0 1.1 9.8 0.3 3.4 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Lactonase PF10282.9 EIM80893.1 - 1.5e-43 149.4 0.0 1.7e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CoA_transf_3 PF02515.17 EIM80894.1 - 5e-102 341.8 0.0 1.1e-101 340.6 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III Rootletin PF15035.6 EIM80895.1 - 0.00099 19.2 11.4 0.0025 17.9 11.4 1.7 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Phlebovirus_NSM PF07246.11 EIM80895.1 - 0.027 13.8 5.3 0.047 13.1 5.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Golgin_A5 PF09787.9 EIM80895.1 - 0.041 13.3 12.3 0.079 12.4 12.3 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Leu_zip PF15294.6 EIM80895.1 - 0.18 11.3 9.9 0.39 10.2 9.5 1.7 1 1 0 1 1 1 0 Leucine zipper GAS PF13851.6 EIM80895.1 - 0.72 9.2 14.4 5.4 6.3 14.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 EIM80895.1 - 0.91 9.8 15.2 0.069 13.4 8.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EIM80895.1 - 2.3 7.0 11.9 1.4 7.7 9.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EIM80895.1 - 2.3 8.4 8.9 0.37 11.0 4.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 EIM80895.1 - 4.1 7.7 8.0 35 4.7 2.9 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper RNA_pol_A_bac PF01000.26 EIM80896.1 - 4.2e-22 78.6 0.0 7.6e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EIM80896.1 - 4.8e-21 74.0 0.0 7.2e-21 73.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M20 PF01546.28 EIM80897.1 - 3.6e-20 72.6 0.0 5.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM80897.1 - 0.00024 21.0 0.0 0.00086 19.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM80897.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 F-box-like PF12937.7 EIM80899.1 - 0.018 14.9 4.5 0.032 14.1 1.1 2.4 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EIM80899.1 - 0.048 13.5 0.3 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 F-box domain Qua1 PF16274.5 EIM80900.1 - 2.3 8.1 4.1 29 4.6 0.6 2.9 2 0 0 2 2 2 0 Qua1 domain Fib_alpha PF08702.10 EIM80900.1 - 4.6 7.4 11.3 0.77 9.9 1.4 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 EIM80902.1 - 0.0076 16.3 6.1 0.0076 16.3 6.1 2.6 2 2 2 4 4 4 1 TPR/MLP1/MLP2-like protein HALZ PF02183.18 EIM80902.1 - 0.19 12.0 4.2 0.12 12.6 1.3 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 EIM80902.1 - 0.21 11.7 3.8 1.5 9.0 0.0 2.9 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 EIM80902.1 - 0.27 10.6 5.2 0.5 9.7 5.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC144C PF14915.6 EIM80902.1 - 0.46 9.5 8.1 0.64 9.1 8.0 1.3 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Seryl_tRNA_N PF02403.22 EIM80902.1 - 0.66 10.2 7.4 4.5 7.6 3.9 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAUS6_N PF14661.6 EIM80902.1 - 8.9 5.8 8.3 1.7 8.1 4.5 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ZapB PF06005.12 EIM80902.1 - 9.5 6.7 9.0 3.4 8.2 3.6 2.4 1 1 1 2 2 2 0 Cell division protein ZapB HtrL_YibB PF09612.10 EIM80904.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3584 PF12128.8 EIM80905.1 - 0.036 11.6 9.3 0.047 11.2 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YabA PF06156.13 EIM80905.1 - 0.11 13.2 0.5 0.11 13.2 0.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 EIM80905.1 - 0.13 11.3 5.2 0.21 10.6 5.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CASP_C PF08172.12 EIM80905.1 - 0.26 10.6 7.5 0.72 9.1 7.4 1.8 1 1 0 1 1 1 0 CASP C terminal Golgin_A5 PF09787.9 EIM80905.1 - 0.28 10.6 11.8 0.51 9.7 11.8 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 IFT57 PF10498.9 EIM80905.1 - 0.35 9.8 9.0 0.54 9.2 9.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 EIM80905.1 - 0.83 9.0 9.5 1.3 8.4 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 EIM80905.1 - 0.96 9.5 7.2 2.7 8.1 7.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.15 EIM80905.1 - 1.1 9.4 9.8 0.24 11.5 4.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Nup88 PF10168.9 EIM80905.1 - 1.1 7.0 6.9 1.5 6.6 6.9 1.1 1 0 0 1 1 1 0 Nuclear pore component Macoilin PF09726.9 EIM80905.1 - 1.3 7.5 10.3 2 6.9 10.3 1.2 1 0 0 1 1 1 0 Macoilin family TSC22 PF01166.18 EIM80905.1 - 1.7 9.0 5.7 0.82 10.0 2.4 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family SOG2 PF10428.9 EIM80905.1 - 2.8 7.1 10.0 3.4 6.7 9.3 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein Seadorna_Vp10 PF07322.11 EIM80906.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus Vp10 F-box-like PF12937.7 EIM80907.1 - 0.0037 17.1 0.0 0.0087 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM80907.1 - 0.0053 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain Metallophos PF00149.28 EIM80908.1 - 1e-12 49.0 4.3 1e-12 49.0 4.3 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EIM80908.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 5'-nucleotidase, C-terminal domain CRF-BP PF05428.11 EIM80909.1 - 0.054 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Abhydrolase_1 PF00561.20 EIM80911.1 - 0.0032 17.1 0.0 0.0035 17.0 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM80911.1 - 0.0034 16.7 0.0 0.0039 16.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Polysacc_lyase PF14099.6 EIM80912.1 - 0.0029 17.5 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase DDE_3 PF13358.6 EIM80914.1 - 9.1e-09 35.2 0.1 4.4e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease Acetyltransf_7 PF13508.7 EIM80915.1 - 9.2e-10 38.8 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM80915.1 - 2.7e-08 33.8 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80915.1 - 3.8e-08 33.6 0.0 4.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EIM80915.1 - 0.0088 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Atg14 PF10186.9 EIM80916.1 - 0.0044 16.2 4.5 0.0087 15.2 4.5 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 EIM80916.1 - 0.065 13.3 14.4 4.3 7.4 13.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C2H2 PF00096.26 EIM80916.1 - 0.091 13.3 6.1 0.13 12.7 0.1 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM80916.1 - 0.094 13.2 1.0 1.2 9.7 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain GAS PF13851.6 EIM80916.1 - 0.23 10.8 8.8 0.55 9.6 8.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0547 PF10571.9 EIM80916.1 - 0.3 11.2 0.2 0.3 11.2 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 SYCE1 PF15233.6 EIM80916.1 - 2.9 8.0 12.6 22 5.1 12.3 2.5 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF1635 PF07795.11 EIM80916.1 - 4.6 7.0 7.5 4.9 7.0 6.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) F-box-like PF12937.7 EIM80918.1 - 8.8e-05 22.3 1.1 0.00017 21.4 0.4 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM80918.1 - 0.056 13.3 0.3 0.2 11.6 0.3 1.9 1 0 0 1 1 1 0 F-box domain Acetyltransf_3 PF13302.7 EIM80919.1 - 1.6e-13 51.5 0.0 1.9e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80919.1 - 0.07 13.4 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EIM80919.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain APH PF01636.23 EIM80920.1 - 1.5e-16 61.1 0.0 2.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM80920.1 - 3.1e-05 23.7 0.0 5.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EIM80920.1 - 0.014 14.2 0.0 0.071 12.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EIM80920.1 - 0.069 12.5 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 EIM80920.1 - 0.19 11.1 0.0 9.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family K_trans PF02705.16 EIM80921.1 - 1e-165 552.3 15.9 1.2e-165 552.1 15.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter APH PF01636.23 EIM80922.1 - 2.3e-19 70.3 0.0 2.7e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM80922.1 - 1.1e-05 25.2 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EIM80922.1 - 0.0073 15.2 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 EIM80922.1 - 0.027 13.9 0.0 0.66 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 EIM80922.1 - 0.18 11.1 0.0 10 5.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4073 PF13285.6 EIM80923.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) SPASM PF13186.6 EIM80923.1 - 0.038 14.5 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain TAF8_C PF10406.9 EIM80925.1 - 0.0063 17.0 0.0 0.043 14.4 0.1 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term U71 PF17474.2 EIM80925.1 - 0.14 12.1 0.3 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Tegument protein UL11 homolog CBM_1 PF00734.18 EIM80926.1 - 4.9e-13 48.8 15.9 1.4e-12 47.4 15.9 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain CsbD PF05532.12 EIM80928.1 - 1.3e-06 28.2 9.9 2.1e-06 27.5 2.1 2.7 1 1 1 2 2 2 2 CsbD-like NAD_binding_4 PF07993.12 EIM80929.1 - 2e-32 112.4 0.0 3.3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM80929.1 - 3.2e-28 98.5 0.0 1.1e-27 96.7 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM80929.1 - 2.4e-13 50.1 0.0 4.6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM80929.1 - 5.4e-05 22.3 0.0 9.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EIM80929.1 - 0.00011 22.4 0.0 0.0003 21.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EIM80929.1 - 0.021 14.3 0.0 0.052 12.9 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EIM80929.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WW_like PF17890.1 EIM80930.1 - 0.029 14.4 0.2 0.09 12.9 0.2 1.8 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain PIF1 PF05970.14 EIM80931.1 - 3.5e-05 23.1 0.0 0.05 12.8 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase SH3_13 PF18335.1 EIM80931.1 - 0.071 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain DUF1340 PF07067.11 EIM80931.1 - 0.13 11.6 0.3 0.53 9.6 0.3 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1340) Methyltransf_25 PF13649.6 EIM80933.1 - 1.1e-06 29.2 0.0 1.5e-05 25.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM80933.1 - 1.4e-06 28.3 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM80933.1 - 1.9e-05 25.2 0.0 4.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM80933.1 - 2.5e-05 24.9 0.0 4.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EIM80933.1 - 0.0088 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 EIM80933.1 - 0.027 13.8 0.0 0.24 10.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.16 EIM80934.1 - 5.9e-17 61.6 40.2 5.9e-17 61.6 40.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EIM80935.1 - 1.2e-44 152.9 0.0 3e-44 151.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 EIM80936.1 - 6.2e-22 78.1 4.8 6.2e-22 78.1 4.8 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 EIM80937.1 - 1.3e-54 185.7 0.0 1.8e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM80938.1 - 4.6e-54 183.9 0.0 1.6e-53 182.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Sec34 PF04136.15 EIM80940.1 - 3.2e-10 40.1 0.0 4.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Sec34-like family Acetyltransf_10 PF13673.7 EIM80941.1 - 5e-06 26.5 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM80941.1 - 5.2e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM80941.1 - 0.00029 21.0 0.0 0.00063 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EIM80941.1 - 0.0056 16.6 0.0 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein GNAT_acetyltran PF12746.7 EIM80941.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_9 PF13527.7 EIM80941.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BTB PF00651.31 EIM80943.1 - 0.013 15.7 0.0 0.05 13.8 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Gp58 PF07902.11 EIM80946.1 - 0.0034 15.7 0.7 0.0039 15.5 0.7 1.1 1 0 0 1 1 1 1 gp58-like protein HDAC4_Gln PF12203.8 EIM80946.1 - 0.4 10.9 8.5 0.23 11.7 5.0 2.4 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 PKcGMP_CC PF16808.5 EIM80946.1 - 1.2 9.0 7.0 18 5.3 0.0 4.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase KELK PF15796.5 EIM80946.1 - 1.3 9.5 11.1 0.13 12.7 5.4 2.2 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MscS_TM PF12794.7 EIM80947.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SKG6 PF08693.10 EIM80953.1 - 3e-05 23.3 0.6 6.5e-05 22.3 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CE2_N PF17996.1 EIM80953.1 - 0.026 14.5 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal PRIMA1 PF16101.5 EIM80953.1 - 0.036 14.1 3.8 0.67 10.0 0.2 3.5 4 0 0 4 4 4 0 Proline-rich membrane anchor 1 LPG_synthase_TM PF03706.13 EIM80953.1 - 0.047 13.2 0.2 0.072 12.6 0.2 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region EphA2_TM PF14575.6 EIM80953.1 - 0.073 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 EIM80953.1 - 0.1 12.4 0.8 0.18 11.6 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AA_permease PF00324.21 EIM80954.1 - 2.6e-117 392.4 43.3 3.2e-117 392.1 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM80954.1 - 5.1e-34 117.8 48.0 6.2e-34 117.6 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3638 PF12340.8 EIM80956.1 - 1.2e-89 299.6 0.7 1.9e-89 298.9 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EIM80956.1 - 8e-17 60.3 0.1 1.6e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Jacalin PF01419.17 EIM80957.1 - 0.06 13.3 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Jacalin-like lectin domain Cu-oxidase PF00394.22 EIM80961.1 - 1.2e-50 171.8 0.2 5.1e-44 150.2 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM80961.1 - 5e-39 133.2 0.9 2.8e-35 121.0 0.0 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM80961.1 - 1.4e-35 121.9 0.3 3.8e-34 117.2 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase DUF2252 PF10009.9 EIM80962.1 - 0.058 12.5 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4148 PF13663.6 EIM80963.1 - 0.012 15.7 0.5 11 6.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Glycos_trans_3N PF02885.17 EIM80963.1 - 0.024 14.5 0.4 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain BST2 PF16716.5 EIM80963.1 - 0.053 14.1 7.9 3 8.5 0.9 2.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Mfp-3 PF04202.13 EIM80963.1 - 0.11 12.9 0.0 28 5.2 0.0 2.3 2 0 0 2 2 2 0 Foot protein 3 Ribosomal_L2_C PF03947.18 EIM80963.1 - 0.26 11.5 7.4 0.73 10.0 2.1 2.3 2 0 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain YpzI PF14140.6 EIM80963.1 - 0.53 10.1 5.7 9.6 6.1 0.5 2.6 2 0 0 2 2 2 0 YpzI-like protein DUF2913 PF11140.8 EIM80963.1 - 4.4 7.0 9.0 12 5.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) DUF4449 PF14613.6 EIM80964.1 - 9e-08 32.4 0.0 9e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) C1_4 PF07975.12 EIM80965.1 - 0.1 12.9 1.1 2.4 8.5 1.4 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zf-HIT PF04438.16 EIM80965.1 - 1 9.3 6.1 2.2 8.3 1.3 2.4 2 0 0 2 2 2 0 HIT zinc finger Zn_ribbon_SprT PF17283.2 EIM80965.1 - 4.4 7.3 9.1 19 5.3 8.1 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain ELP6 PF09807.9 EIM80966.1 - 9.5e-15 54.7 0.0 1.6e-12 47.4 0.0 2.6 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 EIM80966.1 - 0.00019 21.1 0.2 0.0025 17.4 0.2 2.0 1 1 0 1 1 1 1 Elongator subunit Iki1 MAP PF03642.13 EIM80967.1 - 0.091 13.1 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 MAP domain PWWP PF00855.17 EIM80969.1 - 2.5e-19 69.5 0.1 8.3e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 EIM80969.1 - 0.007 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain F-box-like PF12937.7 EIM80971.1 - 5.1e-06 26.3 0.3 1.8e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like p450 PF00067.22 EIM80972.1 - 5.6e-59 200.1 0.0 8.2e-58 196.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sod_Cu PF00080.20 EIM80973.1 - 1.4e-11 44.7 0.1 3.4e-11 43.5 0.1 1.6 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Zn_clus PF00172.18 EIM80976.1 - 5.8e-09 35.9 14.4 5.8e-09 35.9 14.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.20 EIM80977.1 - 1.6e-22 79.6 0.0 2.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zinc_ribbon_9 PF14369.6 EIM80978.1 - 0.26 11.6 8.7 0.073 13.4 4.3 2.3 2 1 1 3 3 3 0 zinc-ribbon Cys_rich_CPCC PF14206.6 EIM80978.1 - 0.67 9.8 3.3 1.3 8.9 3.3 1.4 1 0 0 1 1 1 0 Cysteine-rich CPCC Metallophos PF00149.28 EIM80979.1 - 6.1e-14 53.0 0.4 8.4e-14 52.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM80979.1 - 0.012 15.8 0.1 0.053 13.7 0.0 1.9 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Mem_trans PF03547.18 EIM80981.1 - 2e-22 79.2 5.6 1.4e-12 46.7 0.2 2.6 1 1 0 2 2 2 2 Membrane transport protein C6 PF01681.17 EIM80982.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 C6 domain Lipase_GDSL_2 PF13472.6 EIM80983.1 - 1.8e-12 48.0 1.4 2.2e-12 47.7 1.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIM80983.1 - 9e-06 25.8 0.1 2e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 EIM80983.1 - 0.23 11.1 0.1 13 5.4 0.0 2.1 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX MMtag PF10159.9 EIM80984.1 - 1.6e-29 102.0 2.6 1.6e-29 102.0 2.6 3.2 3 0 0 3 3 3 1 Multiple myeloma tumor-associated NARP1 PF12569.8 EIM80984.1 - 1 8.2 12.7 1.9 7.3 12.7 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glyco_hydro_92 PF07971.12 EIM80985.1 - 1.8e-129 432.7 5.7 1.8e-129 432.7 5.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EIM80985.1 - 1.1e-51 176.0 3.3 1.9e-51 175.2 3.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain zf-MYND PF01753.18 EIM80986.1 - 0.026 14.6 4.1 0.048 13.8 4.1 1.4 1 0 0 1 1 1 0 MYND finger zf-MYND PF01753.18 EIM80987.1 - 2.1e-12 46.9 11.9 3.1e-12 46.4 11.9 1.3 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.18 EIM80989.1 - 5.9e-10 38.6 0.0 9.2e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM80989.1 - 2.7e-08 33.8 9.2 4.5e-08 33.1 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EIM80992.1 - 9.8e-61 205.4 0.1 9e-37 126.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM80992.1 - 2.1e-37 128.9 0.0 9.8e-24 84.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIM80992.1 - 4.8e-05 22.8 0.0 8.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIM80992.1 - 0.082 11.8 0.0 0.082 11.8 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EIM80992.1 - 0.41 10.5 0.0 0.41 10.5 0.0 4.6 4 1 1 5 5 5 0 Phosphotransferase enzyme family zf-MYND PF01753.18 EIM80993.1 - 0.033 14.3 4.3 0.062 13.4 4.3 1.5 1 0 0 1 1 1 0 MYND finger Hydrolase_like PF13242.6 EIM80994.1 - 6e-23 80.7 0.0 1.2e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EIM80994.1 - 2e-22 79.2 0.0 3.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM80994.1 - 0.00015 22.1 0.0 0.96 9.7 0.0 2.9 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 EIM80995.1 - 3.1e-08 33.0 0.0 5.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM80995.1 - 3.3e-06 27.1 4.9 5.6e-06 26.4 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NuDC PF16273.5 EIM80997.1 - 0.13 12.8 0.3 8.4 7.0 0.2 2.3 2 0 0 2 2 2 0 Nuclear distribution C domain DUF1192 PF06698.11 EIM80997.1 - 1.2 9.3 4.5 1.1 9.4 1.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Glyco_hydro_28 PF00295.17 EIM80998.1 - 8.9e-59 199.1 25.9 1.2e-58 198.8 25.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EIM80998.1 - 8.6e-14 51.7 23.0 1.5e-13 50.9 14.9 2.3 2 0 0 2 2 2 2 Right handed beta helix region DUF3403 PF11883.8 EIM80998.1 - 5.3 7.2 10.4 6.8 6.9 0.8 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3403) SMC_N PF02463.19 EIM80999.1 - 3.1e-70 236.0 0.0 4.8e-70 235.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIM80999.1 - 9.3e-24 84.0 0.1 3.1e-23 82.3 0.1 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EIM80999.1 - 4.8e-19 69.7 10.2 4.8e-19 69.7 10.2 6.3 2 2 2 4 4 1 1 AAA domain AAA_21 PF13304.6 EIM80999.1 - 5.8e-16 59.2 1.0 2e-07 31.1 0.1 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM80999.1 - 1.4e-15 57.9 26.7 1.9e-10 41.0 3.6 3.8 2 2 0 2 2 2 2 AAA ATPase domain Tropomyosin_1 PF12718.7 EIM80999.1 - 6.6e-06 26.3 3.7 6.6e-06 26.3 3.7 8.3 2 2 3 7 7 4 1 Tropomyosin like AAA_29 PF13555.6 EIM80999.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nsp1_C PF05064.13 EIM80999.1 - 0.037 13.8 0.2 0.037 13.8 0.2 6.8 7 2 1 8 8 8 0 Nsp1-like C-terminal region DUF3287 PF11690.8 EIM80999.1 - 0.054 13.2 0.2 0.054 13.2 0.2 4.4 5 1 0 5 5 5 0 Protein of unknown function (DUF3287) Val_tRNA-synt_C PF10458.9 EIM80999.1 - 0.088 13.1 0.3 0.088 13.1 0.3 7.6 8 2 0 8 8 7 0 Valyl tRNA synthetase tRNA binding arm GAS PF13851.6 EIM80999.1 - 0.18 11.2 85.6 0.26 10.6 0.4 6.5 3 2 3 6 6 6 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 EIM80999.1 - 0.19 12.3 0.1 0.19 12.3 0.1 5.3 2 2 1 3 3 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 EIM80999.1 - 0.21 10.9 0.0 0.21 10.9 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family LPP PF04728.13 EIM80999.1 - 0.37 11.2 15.1 3.1 8.2 3.0 5.4 4 1 1 5 5 4 0 Lipoprotein leucine-zipper UPF0184 PF03670.13 EIM80999.1 - 0.41 11.1 13.3 2 8.9 1.9 4.9 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) DUF87 PF01935.17 EIM80999.1 - 3.2 7.8 0.0 3.2 7.8 0.0 5.5 3 2 1 5 5 4 0 Helicase HerA, central domain DUF3533 PF12051.8 EIM81000.1 - 1.1e-82 278.0 20.7 6e-73 245.9 16.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) XPA_C PF05181.12 EIM81002.1 - 0.033 14.2 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 XPA protein C-terminus Acetyltransf_15 PF17013.5 EIM81002.1 - 0.055 12.9 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Plavaka PF18759.1 EIM81004.1 - 6.8e-115 383.7 0.0 9.5e-115 383.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase F-box-like PF12937.7 EIM81005.1 - 4.3e-06 26.5 0.1 1.6e-05 24.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EIM81005.1 - 0.052 13.3 1.6 15 5.4 0.0 4.0 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 EIM81005.1 - 0.068 13.6 9.4 1.6 9.3 0.2 5.2 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) DUF3533 PF12051.8 EIM81006.1 - 2.9e-60 204.2 18.2 1.9e-45 155.4 16.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) FA_desaturase PF00487.24 EIM81007.1 - 1.4e-22 80.7 14.4 1.8e-22 80.4 13.2 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EIM81007.1 - 3e-19 68.2 0.8 5e-19 67.5 0.8 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Thymidylat_synt PF00303.19 EIM81008.1 - 9.7e-106 352.8 0.0 1.1e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF4282 PF14110.6 EIM81009.1 - 0.43 11.3 3.0 0.67 10.7 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) PP2C PF00481.21 EIM81010.1 - 8.6e-33 114.1 0.0 1.3e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EIM81010.1 - 0.015 15.3 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) G-alpha PF00503.20 EIM81013.1 - 2.1e-42 145.6 0.0 2.5e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit G-alpha PF00503.20 EIM81014.1 - 6.7e-120 400.5 0.1 7.8e-120 400.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM81014.1 - 2.5e-16 59.6 2.5 1.1e-11 44.5 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIM81014.1 - 5.8e-05 22.6 2.0 0.0018 17.7 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EIM81014.1 - 0.011 16.0 2.4 2.6 8.3 0.1 2.9 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EIM81014.1 - 0.046 13.8 0.0 2.5 8.2 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EIM81014.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.20 EIM81014.1 - 0.11 12.3 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.18 EIM81014.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family p450 PF00067.22 EIM81015.1 - 6.9e-63 213.0 0.0 8.6e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp-B-Hydro_N PF05279.11 EIM81015.1 - 0.24 11.5 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sec2p PF06428.11 EIM81016.1 - 4.6e-05 23.3 1.2 4.6e-05 23.3 1.2 2.4 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p T3SS_ATPase_C PF18269.1 EIM81016.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Rootletin PF15035.6 EIM81016.1 - 0.1 12.6 9.7 0.078 13.0 0.6 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 EIM81016.1 - 0.35 11.5 5.7 2.1 9.0 1.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA HOOK PF05622.12 EIM81016.1 - 0.37 8.9 9.0 0.025 12.8 1.8 1.9 2 0 0 2 2 2 0 HOOK protein DUF4355 PF14265.6 EIM81016.1 - 1.6 8.9 5.8 0.26 11.5 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Spc7 PF08317.11 EIM81016.1 - 1.9 7.3 9.8 0.19 10.6 3.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 EIM81016.1 - 2.2 8.6 15.3 8.6 6.7 0.1 4.7 4 1 1 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 DUF1640 PF07798.11 EIM81016.1 - 3.2 7.8 7.3 0.31 11.1 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Cyt-b5 PF00173.28 EIM81018.1 - 7.5e-12 45.2 0.0 8.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RNA_pol_Rpb5_C PF01191.19 EIM81018.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain CVNH PF08881.10 EIM81019.1 - 9.8e-05 23.0 0.2 0.00021 21.9 0.2 1.6 1 1 0 1 1 1 1 CVNH domain PNPase_C PF12111.8 EIM81019.1 - 3 7.3 4.7 5.6 6.5 1.0 2.4 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal LRR_9 PF14580.6 EIM81023.1 - 0.049 13.1 1.1 5.5 6.5 0.0 3.4 3 2 1 4 4 4 0 Leucine-rich repeat adh_short PF00106.25 EIM81024.1 - 5.8e-20 71.6 0.0 7e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81024.1 - 1.2e-10 41.3 0.0 1.4e-07 31.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81024.1 - 0.00048 20.1 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 KR domain VEGFR-2_TMD PF17988.1 EIM81025.1 - 0.35 10.4 2.9 0.7 9.4 2.9 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Pkinase PF00069.25 EIM81026.1 - 1.1e-28 100.3 0.0 6e-28 97.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81026.1 - 3.4e-08 33.1 0.0 6.5e-06 25.6 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EIM81027.1 - 3.8e-27 95.3 0.0 8.8e-27 94.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81027.1 - 2e-09 37.1 0.0 1.1e-06 28.2 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase zf_C2H2_6 PF18450.1 EIM81027.1 - 0.069 12.9 1.8 0.12 12.1 0.6 2.0 2 0 0 2 2 2 0 Zinc Finger domain Mago-bind PF09282.10 EIM81027.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Mago binding SDP_N PF12278.8 EIM81031.1 - 0.51 10.5 1.6 0.6 10.2 1.6 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal zf-MYND PF01753.18 EIM81034.1 - 6e-07 29.5 11.5 1.5e-06 28.2 11.5 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 EIM81036.1 - 0.0001 22.1 0.1 0.00027 20.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like Mto2_bdg PF12808.7 EIM81036.1 - 0.32 11.3 1.7 0.63 10.4 1.7 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region p450 PF00067.22 EIM81037.1 - 1.4e-65 221.9 0.0 1.8e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_3 PF13641.6 EIM81039.1 - 1.5e-29 103.6 0.0 2.1e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIM81039.1 - 4.7e-08 33.0 0.0 7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIM81039.1 - 1.2e-05 24.9 0.1 6.7e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 hNIFK_binding PF12196.8 EIM81040.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK DUF5540 PF17694.1 EIM81040.1 - 0.096 13.2 0.2 0.14 12.7 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5540) DSRB PF10781.9 EIM81041.1 - 0.16 11.6 0.2 14 5.4 0.0 3.5 4 0 0 4 4 4 0 Dextransucrase DSRB IBR PF01485.21 EIM81045.1 - 1.9e-14 53.6 41.2 2.9e-09 37.0 16.6 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EIM81045.1 - 7e-06 25.8 1.7 7e-06 25.8 1.7 4.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM81045.1 - 8e-05 22.6 3.0 8e-05 22.6 3.0 4.3 3 2 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIM81045.1 - 0.00017 21.4 5.5 0.00017 21.4 5.5 4.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM81045.1 - 0.0058 16.9 5.9 0.0058 16.9 5.9 3.9 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 EIM81045.1 - 0.0067 16.3 4.3 0.0067 16.3 4.3 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM81045.1 - 0.0084 16.2 2.2 0.0084 16.2 2.2 4.4 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EIM81045.1 - 9.4 6.1 20.1 5.2 6.9 3.5 3.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DciA PF05258.12 EIM81046.1 - 0.035 14.5 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA p450 PF00067.22 EIM81048.1 - 3.1e-52 177.9 0.1 6.9e-34 117.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 AA_permease PF00324.21 EIM81052.1 - 3.1e-126 421.8 39.5 3.5e-126 421.6 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM81052.1 - 7.2e-38 130.5 45.2 8.5e-38 130.3 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 EIM81053.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM81053.1 - 0.012 15.5 0.7 0.033 14.1 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EIM81053.1 - 0.03 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 EIM81053.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 EIM81053.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4064 PF13273.6 EIM81054.1 - 0.027 14.7 0.4 0.027 14.7 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF5326 PF17260.2 EIM81054.1 - 0.2 11.8 0.1 0.2 11.8 0.1 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5326) DUF5316 PF17247.2 EIM81054.1 - 3 7.9 5.4 1 9.4 0.4 2.8 2 2 0 2 2 2 0 Family of unknown function (DUF5316) HSP70 PF00012.20 EIM81055.1 - 4.4e-162 540.4 0.1 4.4e-162 540.4 0.1 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EIM81055.1 - 2.3e-09 36.5 0.0 8.8e-09 34.6 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Pkinase PF00069.25 EIM81056.1 - 2.7e-61 207.2 0.0 3.6e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81056.1 - 1.2e-31 109.9 0.0 1.9e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EIM81056.1 - 7.7e-15 55.0 0.3 1.6e-14 54.0 0.3 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EIM81056.1 - 2.6e-07 30.2 0.4 1.2e-06 28.1 0.1 2.1 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 EIM81056.1 - 6.2e-06 26.4 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EIM81056.1 - 0.00051 19.4 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM81056.1 - 0.0032 17.4 0.0 0.086 12.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM81056.1 - 0.0042 16.1 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EIM81056.1 - 0.061 12.9 0.0 4 7.0 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Alpha_GJ PF03229.13 EIM81056.1 - 0.16 12.6 2.6 0.4 11.2 1.3 2.4 3 0 0 3 3 3 0 Alphavirus glycoprotein J F-box PF00646.33 EIM81057.1 - 0.0017 18.2 0.0 0.0055 16.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EIM81057.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box Acetyltransf_9 PF13527.7 EIM81058.1 - 0.00026 21.1 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM81058.1 - 0.00042 20.7 0.0 0.00069 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM81058.1 - 0.00053 20.2 0.0 0.00066 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM81058.1 - 0.00071 19.5 0.0 0.00096 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM81058.1 - 0.03 14.5 0.1 0.053 13.7 0.0 1.5 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EIM81058.1 - 0.17 11.8 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Mannosyl_trans PF05007.13 EIM81059.1 - 0.0035 17.2 1.0 0.0035 17.2 1.0 1.4 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) GBR2_CC PF18455.1 EIM81060.1 - 0.025 14.7 0.1 0.12 12.5 0.1 2.2 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF3328 PF11807.8 EIM81061.1 - 2.4e-39 135.4 0.1 2.7e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PC-Esterase PF13839.6 EIM81062.1 - 4.2e-07 30.0 0.0 0.0058 16.4 0.0 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p AAA_16 PF13191.6 EIM81063.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 EIM81063.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 EIM81063.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Lyase_aromatic PF00221.19 EIM81064.1 - 5.6e-147 490.2 4.0 7.2e-147 489.8 4.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase F-box-like PF12937.7 EIM81065.1 - 3e-06 27.0 2.4 4.8e-06 26.4 2.0 1.6 1 1 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 EIM81067.1 - 2e-89 300.6 25.3 2.3e-89 300.4 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM81067.1 - 3.5e-32 111.7 43.5 9.7e-26 90.5 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 EIM81069.1 - 1.8e-41 142.1 0.0 2.5e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EIM81069.1 - 4.5e-35 121.1 0.0 1.1e-34 119.9 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EIM81069.1 - 8.1e-21 73.9 1.1 2.3e-20 72.4 1.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EIM81069.1 - 3.1e-18 66.7 0.0 1.3e-17 64.6 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain NOG1_N PF17835.1 EIM81070.1 - 9.6e-51 171.9 1.3 2e-50 170.9 1.3 1.6 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EIM81070.1 - 5.1e-28 96.8 2.3 5.1e-28 96.8 2.3 2.3 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 EIM81070.1 - 1.9e-27 94.8 0.1 4.6e-27 93.6 0.1 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EIM81070.1 - 2e-17 63.3 0.0 4.4e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM81070.1 - 1.2e-08 34.7 0.0 2.7e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIM81070.1 - 0.011 15.6 0.0 0.76 9.7 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 EIM81070.1 - 0.024 14.7 0.0 1.8 8.6 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Sushi_2 PF09014.10 EIM81070.1 - 0.063 13.2 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 EIM81070.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 EIM81070.1 - 0.14 12.4 0.0 1.2 9.4 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EIM81071.1 - 1.5e-108 363.2 0.1 1.7e-108 362.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM81071.1 - 2.1e-09 37.1 0.0 2.9e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIM81071.1 - 0.0078 15.6 0.5 0.87 8.9 0.0 2.7 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EIM81071.1 - 0.042 13.8 0.7 6.1 6.7 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase TniB PF05621.11 EIM81071.1 - 0.045 13.2 0.1 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 EIM81071.1 - 0.047 12.8 0.4 0.1 11.7 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 EIM81071.1 - 0.055 13.4 0.0 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 EIM81071.1 - 0.065 13.5 0.0 0.39 10.9 0.0 2.1 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EIM81071.1 - 0.21 11.4 0.8 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DASH_Dad4 PF08650.10 EIM81073.1 - 2.5e-25 88.2 1.4 3e-25 88.0 1.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 APOBEC4 PF18775.1 EIM81073.1 - 0.034 14.3 0.3 0.049 13.8 0.3 1.3 1 1 0 1 1 1 0 APOBEC4 COX17 PF05051.13 EIM81073.1 - 0.14 12.5 0.2 0.37 11.2 0.1 1.7 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) zinc_ribbon_16 PF17034.5 EIM81074.1 - 2.3e-17 63.3 7.5 6e-17 62.0 7.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 EIM81074.1 - 0.01 16.1 0.0 5.5 7.4 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM81074.1 - 0.02 15.8 9.4 0.75 10.8 0.1 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EIM81074.1 - 0.11 12.2 10.3 0.012 15.2 5.3 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Methyltransf_2 PF00891.18 EIM81075.1 - 3e-12 46.3 0.0 1.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase domain AbiEi_4 PF13338.6 EIM81075.1 - 3.3e-05 24.0 0.0 0.0091 16.1 0.0 2.7 2 0 0 2 2 2 2 Transcriptional regulator, AbiEi antitoxin Methyltransf_16 PF10294.9 EIM81075.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase MarR PF01047.22 EIM81075.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 MarR family SMC_Nse1 PF07574.13 EIM81075.1 - 0.024 14.5 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Methyltransf_25 PF13649.6 EIM81075.1 - 0.079 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 EIM81076.1 - 1e-07 31.7 0.1 3e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81076.1 - 0.005 16.7 2.4 0.022 14.6 0.1 3.1 3 0 0 3 3 3 1 F-box domain BRCT_2 PF16589.5 EIM81077.1 - 2.3e-08 34.3 0.0 6.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIM81077.1 - 0.0011 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rap1-DNA-bind PF09197.10 EIM81077.1 - 0.045 14.3 6.4 2.3 8.8 1.3 3.4 2 1 1 3 3 3 0 Rap1, DNA-binding PH_10 PF15411.6 EIM81079.1 - 7.1e-39 132.9 0.0 1.4e-38 131.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EIM81079.1 - 9.3e-36 123.8 2.0 1.5e-35 123.1 2.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EIM81079.1 - 1.1e-12 47.7 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 EIM81079.1 - 1.5e-11 44.4 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin She9_MDM33 PF05546.11 EIM81079.1 - 0.046 13.5 0.5 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 She9 / Mdm33 family SelP_N PF04592.14 EIM81079.1 - 0.67 9.3 8.6 1.6 8.1 8.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MMR_HSR1 PF01926.23 EIM81080.1 - 3.1e-06 27.2 0.0 5.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EIM81080.1 - 3.2e-05 23.7 0.0 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 EIM81080.1 - 0.0032 17.0 0.0 0.0075 15.7 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Septin PF00735.18 EIM81080.1 - 0.0086 15.4 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 1 Septin AAA PF00004.29 EIM81080.1 - 0.0094 16.4 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EIM81080.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EIM81080.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 EIM81080.1 - 0.046 13.5 0.0 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EIM81080.1 - 0.048 13.9 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EIM81080.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 EIM81080.1 - 0.054 12.6 0.0 0.48 9.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 EIM81080.1 - 0.068 13.7 0.0 0.11 13.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 EIM81080.1 - 0.076 12.5 0.0 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EIM81080.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 EIM81084.1 - 5.9e-68 224.9 10.4 3.7e-24 84.5 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIM81084.1 - 0.00025 20.3 1.5 1.1 8.4 0.0 4.0 2 2 0 4 4 4 3 Gammaproteobacterial serine protease DUF1180 PF06679.12 EIM81084.1 - 0.18 12.2 3.1 0.34 11.3 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HTH_18 PF12833.7 EIM81085.1 - 0.06 13.6 0.2 6.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain FAD_binding_4 PF01565.23 EIM81086.1 - 0.0083 15.9 6.7 0.79 9.5 0.4 3.1 2 1 0 2 2 2 2 FAD binding domain Glyco_hydro_63 PF03200.16 EIM81088.1 - 2.7e-08 33.0 10.7 1.1e-06 27.7 0.4 4.7 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain AAA_22 PF13401.6 EIM81089.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EIM81089.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EIM81089.1 - 0.096 11.8 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PPV_E1_C PF00519.17 EIM81089.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RhoGAP PF00620.27 EIM81090.1 - 8.2e-29 100.4 0.0 3e-28 98.6 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.16 EIM81092.1 - 1.5e-44 152.3 47.5 2.1e-44 151.9 47.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81092.1 - 3e-19 69.2 30.9 1.6e-17 63.5 7.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EIM81092.1 - 2.5e-13 49.3 23.1 4.7e-13 48.4 23.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EMC3_TMCO1 PF01956.16 EIM81092.1 - 0.096 12.4 2.5 1.8 8.2 0.2 2.5 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like AAA_16 PF13191.6 EIM81093.1 - 0.0073 16.7 0.1 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EIM81093.1 - 0.017 14.8 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EIM81093.1 - 0.023 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EIM81093.1 - 0.033 13.5 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EIM81093.1 - 0.034 13.9 0.1 0.059 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EIM81093.1 - 0.044 13.6 0.0 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIM81093.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EIM81093.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EIM81093.1 - 0.087 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 EIM81093.1 - 0.09 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EIM81093.1 - 0.094 13.2 0.1 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.7 EIM81093.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.6 EIM81093.1 - 0.14 12.5 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain RPEL PF02755.15 EIM81095.1 - 5.9e-15 54.4 7.6 3.1e-07 29.9 1.6 2.6 2 0 0 2 2 2 2 RPEL repeat DUF1279 PF06916.13 EIM81096.1 - 4.4e-15 56.0 0.0 1e-14 54.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Sporozoite_P67 PF05642.11 EIM81096.1 - 0.18 9.8 0.0 0.26 9.3 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zn_clus PF00172.18 EIM81097.1 - 2.9e-08 33.7 29.4 0.00011 22.3 7.6 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM27 PF15832.5 EIM81097.1 - 0.067 13.7 6.1 0.95 10.0 5.5 2.7 2 0 0 2 2 2 0 FAM27 D and E protein family PRP38_assoc PF12871.7 EIM81097.1 - 1.3 9.6 13.2 0.88 10.2 8.1 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Dfp1_Him1_M PF08630.10 EIM81099.1 - 5.6e-31 107.4 0.0 5.6e-31 107.4 0.0 2.6 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EIM81099.1 - 2.4e-20 72.4 0.9 4.3e-20 71.5 0.9 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EIM81099.1 - 0.0054 17.1 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EIM81099.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain zf-ACC PF17848.1 EIM81100.1 - 1.3e-05 25.2 12.0 0.4 10.8 0.2 4.5 4 0 0 4 4 4 3 Acetyl-coA carboxylase zinc finger domain Mut7-C PF01927.16 EIM81100.1 - 0.0097 16.0 0.9 14 5.8 0.1 3.3 3 0 0 3 3 3 1 Mut7-C RNAse domain zf-Di19 PF05605.12 EIM81100.1 - 0.021 15.1 16.9 3.9 7.8 0.1 5.1 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 EIM81100.1 - 0.027 13.9 6.0 4.2 6.9 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain DUF3797 PF12677.7 EIM81100.1 - 0.075 12.9 2.2 15 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) DUF1178 PF06676.11 EIM81100.1 - 0.087 13.2 7.7 9.7 6.6 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) zf-C3HC PF07967.13 EIM81100.1 - 0.21 11.7 2.6 29 4.7 0.1 3.5 4 0 0 4 4 4 0 C3HC zinc finger-like zf-C4_Topoisom PF01396.19 EIM81100.1 - 1 9.2 12.5 1.9 8.3 0.2 4.1 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger Rubredoxin PF00301.20 EIM81100.1 - 1.7 8.7 5.6 9.5 6.3 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin zinc_ribbon_4 PF13717.6 EIM81100.1 - 2.8 7.9 14.5 8.5 6.4 0.0 5.2 5 0 0 5 5 5 0 zinc-ribbon domain zf_UBZ PF18439.1 EIM81100.1 - 2.8 7.6 13.9 9.4 5.9 0.0 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 EIM81100.1 - 3.3 8.0 6.5 21 5.5 0.0 3.9 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain OrsD PF12013.8 EIM81100.1 - 3.7 8.0 15.4 8.3 6.9 0.0 4.9 5 0 0 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D RmlD_sub_bind PF04321.17 EIM81101.1 - 3.4e-53 180.6 0.0 4.1e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EIM81101.1 - 9.6e-22 77.6 0.0 1.2e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EIM81101.1 - 1e-08 34.7 0.0 3.9e-07 29.5 0.0 2.5 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EIM81101.1 - 1e-08 35.0 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM81101.1 - 0.006 15.8 0.0 0.1 11.7 0.0 2.7 2 1 1 3 3 3 1 Male sterility protein DapB_N PF01113.20 EIM81101.1 - 0.029 14.5 0.1 0.15 12.2 0.0 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PilJ PF13675.6 EIM81103.1 - 0.023 14.7 1.5 0.065 13.3 1.5 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term TSA PF03249.13 EIM81103.1 - 0.32 9.7 1.6 0.46 9.2 1.6 1.1 1 0 0 1 1 1 0 Type specific antigen DUF5401 PF17380.2 EIM81103.1 - 3.2 5.7 15.3 4.6 5.2 15.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PP2C PF00481.21 EIM81104.1 - 1.6e-23 83.7 0.0 3.2e-22 79.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EIM81104.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SAM_decarbox PF01536.16 EIM81105.1 - 3.4e-112 375.0 0.0 1.1e-111 373.3 0.0 1.7 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase SH3BGR PF04908.15 EIM81106.1 - 0.85 9.8 2.5 2.2 8.5 0.9 2.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein zf-C2H2_2 PF12756.7 EIM81108.1 - 7.1e-35 119.4 11.9 1.7e-29 102.1 0.1 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EIM81108.1 - 1e-08 35.3 2.0 1e-08 35.3 2.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EIM81108.1 - 2.7e-08 33.9 15.8 2.8e-07 30.6 1.6 3.8 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EIM81108.1 - 7.7e-05 23.2 14.4 0.012 16.4 0.2 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIM81108.1 - 0.002 18.1 0.5 0.002 18.1 0.5 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger ARS2 PF04959.13 EIM81108.1 - 0.0099 16.3 2.8 0.013 15.9 0.2 2.6 3 0 0 3 3 3 1 Arsenite-resistance protein 2 zf-C2H2 PF00096.26 EIM81108.1 - 0.01 16.2 0.8 0.01 16.2 0.8 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zf_RING PF16744.5 EIM81108.1 - 0.029 14.5 1.6 2.5 8.3 0.0 2.9 2 0 0 2 2 2 0 KIAA1045 RING finger CNDH2_C PF16858.5 EIM81108.1 - 1.5 8.6 19.5 2.4 8.0 2.7 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rax2 PF12768.7 EIM81109.1 - 5.2e-46 156.8 21.1 1.9e-45 155.0 4.0 6.1 5 1 1 6 6 6 2 Cortical protein marker for cell polarity SH3_1 PF00018.28 EIM81109.1 - 5.9e-09 35.4 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM81109.1 - 6.3e-07 29.1 0.1 1.8e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 EIM81109.1 - 0.0014 18.8 8.8 1 9.8 0.1 6.0 5 0 0 5 5 5 1 Kelch motif SH3_2 PF07653.17 EIM81109.1 - 0.0095 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Reg_prop PF07494.11 EIM81109.1 - 0.098 12.9 4.7 3.4 8.2 0.1 4.5 4 0 0 4 4 4 0 Two component regulator propeller ABC_membrane_3 PF13748.6 EIM81109.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region TPR_2 PF07719.17 EIM81110.1 - 1.4e-09 37.3 0.7 0.001 19.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SET PF00856.28 EIM81110.1 - 3.8e-08 33.9 0.0 1.1e-07 32.4 0.0 1.8 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 EIM81110.1 - 2.6e-06 27.0 0.1 0.075 12.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM81110.1 - 0.00012 22.7 1.2 0.57 10.9 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM81110.1 - 0.001 19.3 1.1 0.013 15.8 0.5 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM81110.1 - 0.0042 17.5 0.0 0.011 16.3 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM81110.1 - 0.02 14.9 0.2 0.17 12.0 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM81110.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 EIM81110.1 - 0.17 11.6 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TP6A_N PF04406.14 EIM81111.1 - 1e-21 76.7 0.0 1.9e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Rax2 PF12768.7 EIM81112.1 - 0.00063 19.3 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TraL PF07178.11 EIM81112.1 - 0.21 12.1 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 TraL protein Amnionless PF14828.6 EIM81112.1 - 0.28 10.0 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless BTB PF00651.31 EIM81113.1 - 0.015 15.5 0.9 0.055 13.7 0.9 1.8 1 1 0 1 1 1 0 BTB/POZ domain Phytochelatin PF05023.14 EIM81113.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Phytochelatin synthase AAA_22 PF13401.6 EIM81114.1 - 3e-11 43.8 0.0 7.9e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EIM81114.1 - 5.5e-10 39.8 0.1 2.4e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM81114.1 - 7.7e-07 29.6 0.6 7.1e-05 23.2 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EIM81114.1 - 2.4e-05 24.3 0.1 6.1e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 NACHT domain TniB PF05621.11 EIM81114.1 - 6.9e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein NB-ARC PF00931.22 EIM81114.1 - 0.00046 19.4 0.1 0.00082 18.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 EIM81114.1 - 0.0015 18.8 0.1 0.0098 16.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM81114.1 - 0.0025 17.6 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EIM81114.1 - 0.0095 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EIM81114.1 - 0.017 15.1 0.4 0.08 12.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EIM81114.1 - 0.019 14.2 0.1 0.93 8.7 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 EIM81114.1 - 0.024 14.5 0.8 0.12 12.3 0.1 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EIM81114.1 - 0.029 14.8 0.0 0.087 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_2 PF07724.14 EIM81114.1 - 0.036 14.2 0.1 0.099 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) cobW PF02492.19 EIM81114.1 - 0.044 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EIM81114.1 - 0.072 13.6 0.1 0.23 12.0 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EIM81114.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EIM81114.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cdc6_C PF09079.11 EIM81114.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Rad17 PF03215.15 EIM81114.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Pigment_DH PF06324.11 EIM81115.1 - 0.32 11.2 1.2 0.48 10.6 0.2 1.8 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) GCP_C_terminal PF04130.13 EIM81116.1 - 4.6e-54 184.0 0.0 8.3e-54 183.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal BTB PF00651.31 EIM81117.1 - 6e-05 23.2 0.1 0.00064 19.9 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain F-box-like PF12937.7 EIM81119.1 - 7.5e-06 25.8 0.2 8e-05 22.5 0.1 2.7 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EIM81119.1 - 0.0076 16.6 7.2 6.2 7.4 0.2 6.2 5 1 3 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM81119.1 - 0.026 14.3 0.9 4.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat Uds1 PF15456.6 EIM81119.1 - 0.13 12.5 0.2 0.43 10.7 0.1 1.9 2 0 0 2 2 2 0 Up-regulated During Septation PikAIV_N PF18605.1 EIM81119.1 - 0.86 9.2 5.2 1.8 8.2 5.2 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain OPT PF03169.15 EIM81122.1 - 7.9e-154 513.6 40.3 9e-154 513.4 40.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OSCP PF00213.18 EIM81123.1 - 1e-39 136.4 1.9 1.2e-39 136.2 1.9 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit SET PF00856.28 EIM81124.1 - 5.6e-15 56.1 0.2 7.4e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 SET domain KdpC PF02669.15 EIM81124.1 - 0.0022 17.9 0.3 0.0036 17.2 0.3 1.2 1 0 0 1 1 1 1 K+-transporting ATPase, c chain PIG-U PF06728.13 EIM81126.1 - 4.5e-105 351.8 21.8 5.6e-105 351.5 21.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EIM81126.1 - 2.7 7.6 6.7 14 5.3 6.7 2.1 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain F-box-like PF12937.7 EIM81127.1 - 0.00028 20.7 2.1 0.0013 18.6 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM81127.1 - 0.00032 20.5 0.3 0.001 18.8 0.3 1.8 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 EIM81131.1 - 1.2e-14 54.0 10.1 1.2e-14 54.0 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4577 PF15145.6 EIM81131.1 - 0.13 12.3 0.0 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Inhibitor_I9 PF05922.16 EIM81134.1 - 3e-05 24.6 0.0 5.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 HhH-GPD PF00730.25 EIM81135.1 - 1.5e-13 51.1 0.0 3.6e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SLAC1 PF03595.17 EIM81137.1 - 5.5e-81 272.3 46.7 6.3e-81 272.1 46.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PRA1 PF03208.19 EIM81141.1 - 9.1e-36 122.6 0.4 1e-35 122.5 0.4 1.0 1 0 0 1 1 1 1 PRA1 family protein YwiC PF14256.6 EIM81141.1 - 0.039 14.3 0.6 0.039 14.3 0.6 2.0 2 0 0 2 2 2 0 YwiC-like protein Ribosomal_60s PF00428.19 EIM81142.1 - 0.0032 18.0 0.3 0.0033 18.0 0.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein ANAPC_CDC26 PF10471.9 EIM81142.1 - 0.056 14.3 0.8 0.11 13.4 0.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 TPR_1 PF00515.28 EIM81143.1 - 1.2e-18 66.1 1.3 0.0061 16.3 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM81143.1 - 1e-13 50.2 6.4 0.039 14.1 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EIM81143.1 - 2.9e-13 49.4 8.4 0.0051 17.5 0.0 6.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIM81143.1 - 5.2e-13 48.4 3.0 0.034 14.5 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM81143.1 - 9e-12 44.2 0.1 0.39 11.1 0.0 5.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EIM81143.1 - 3.1e-11 43.6 1.1 1.4e-05 25.5 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM81143.1 - 7.1e-11 41.6 2.5 0.045 13.4 0.2 5.2 5 0 0 5 5 5 2 TPR repeat TPR_16 PF13432.6 EIM81143.1 - 1.6e-09 38.2 5.9 0.00026 21.6 0.1 4.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EIM81143.1 - 7e-08 32.6 2.4 0.0058 16.9 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 EIM81143.1 - 3.8e-07 30.3 1.7 0.0076 16.6 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EIM81143.1 - 0.0004 20.5 1.2 0.041 14.0 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM81143.1 - 0.0019 18.4 0.2 0.1 12.8 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIM81143.1 - 0.0022 17.9 0.5 32 4.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM81143.1 - 0.062 13.2 7.3 15 5.6 0.2 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EIM81143.1 - 0.076 12.2 2.6 1.7 7.8 2.6 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF1641 PF07849.11 EIM81143.1 - 0.27 11.1 1.7 16 5.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1641) zf-C2H2 PF00096.26 EIM81144.1 - 1e-11 44.6 13.2 0.00036 20.8 0.3 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM81144.1 - 4.5e-08 33.3 11.3 0.0076 17.0 0.2 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM81144.1 - 1.4e-07 31.6 11.7 1.2e-05 25.5 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EIM81144.1 - 1.6e-05 24.8 6.6 0.026 14.5 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 EIM81144.1 - 0.0062 16.8 2.3 0.34 11.2 1.2 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.18 EIM81144.1 - 0.01 16.5 4.7 0.047 14.4 4.7 2.0 1 1 0 1 1 1 0 TRAF-type zinc finger FAM217 PF15344.6 EIM81144.1 - 0.035 14.1 0.2 0.041 13.8 0.2 1.1 1 0 0 1 1 1 0 FAM217 family zf-met PF12874.7 EIM81144.1 - 0.08 13.4 4.7 2.1 8.8 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 EIM81144.1 - 0.27 11.5 9.0 1.9 8.7 5.7 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_aberr PF17017.5 EIM81144.1 - 0.3 11.2 5.2 2.6 8.1 0.0 2.9 1 1 1 3 3 3 0 Aberrant zinc-finger zf-BED PF02892.15 EIM81144.1 - 0.85 9.7 5.8 1.2 9.2 0.8 2.5 1 1 0 2 2 2 0 BED zinc finger FOXP-CC PF16159.5 EIM81144.1 - 2.5 8.8 7.8 16 6.2 2.2 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 EIM81144.1 - 4.6 7.4 8.6 25 5.1 4.7 2.8 1 1 2 3 3 2 0 Zinc ribbon domain zf-LYAR PF08790.11 EIM81144.1 - 6.7 6.7 6.4 16 5.5 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zinc_ribbon_9 PF14369.6 EIM81144.1 - 8.3 6.8 11.0 1.1 9.6 1.0 3.1 3 1 0 3 3 3 0 zinc-ribbon Abhydrolase_3 PF07859.13 EIM81145.1 - 2.6e-27 96.1 0.0 1.3e-18 67.6 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Allantoicase PF03561.15 EIM81146.1 - 1.4e-89 297.4 0.0 7.3e-44 149.2 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 EIM81146.1 - 1.7e-44 151.9 0.0 2.6e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase F5_F8_type_C PF00754.25 EIM81146.1 - 0.00032 20.8 0.0 0.95 9.6 0.0 2.6 2 0 0 2 2 2 2 F5/8 type C domain Pheromone PF08015.11 EIM81146.1 - 8.8 7.5 8.8 25 6.0 4.7 2.7 2 0 0 2 2 2 0 Fungal mating-type pheromone SOG2 PF10428.9 EIM81147.1 - 0.00062 19.1 1.2 0.00095 18.5 1.2 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein COG6 PF06419.11 EIM81148.1 - 0.096 10.9 0.1 0.12 10.6 0.1 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 RTT107_BRCT_6 PF16771.5 EIM81148.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Zn_clus PF00172.18 EIM81151.1 - 1.9e-05 24.6 10.6 3.1e-05 24.0 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EIM81151.1 - 0.0025 17.8 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PrmC_N PF17827.1 EIM81152.1 - 1.3e-05 25.7 0.3 3.3e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 EIM81152.1 - 0.00019 21.2 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM81152.1 - 0.00087 18.9 0.0 0.004 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EIM81152.1 - 0.0014 19.3 0.0 0.0032 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 EIM81152.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_10 PF05971.12 EIM81152.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase Peptidase_M17 PF00883.21 EIM81157.1 - 3.5e-120 401.0 0.0 4.3e-120 400.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EIM81157.1 - 0.0001 22.1 0.7 0.0002 21.2 0.7 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Alpha-L-AF_C PF06964.12 EIM81159.1 - 2.7e-35 122.0 0.7 6.3e-35 120.8 0.1 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 EIM81159.1 - 0.022 15.0 1.5 0.022 15.0 1.5 2.7 2 0 0 2 2 2 0 Carbohydrate binding domain GFO_IDH_MocA PF01408.22 EIM81160.1 - 3.3e-22 79.6 0.1 6.4e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIM81160.1 - 0.00012 22.7 0.2 0.00018 22.1 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Coilin_N PF15862.5 EIM81160.1 - 0.019 14.8 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus HMG_box PF00505.19 EIM81161.1 - 1.2e-07 32.0 3.0 1e-05 25.9 1.5 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM81161.1 - 0.00047 20.7 0.7 0.00073 20.1 0.3 1.5 2 0 0 2 2 2 1 HMG-box domain Proteasome PF00227.26 EIM81162.1 - 1.9e-55 187.3 0.1 4.7e-55 186.0 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIM81162.1 - 1.5e-13 50.1 0.1 2.9e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature F-box-like PF12937.7 EIM81163.1 - 8.5e-11 41.6 2.0 1.5e-10 40.8 0.9 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM81163.1 - 1.1e-06 28.3 0.1 3.6e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EIM81164.1 - 2.1e-26 91.6 12.4 4.7e-06 27.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM81164.1 - 2.8e-08 34.0 0.1 0.05 13.9 0.0 4.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIM81164.1 - 5.2e-05 22.7 0.0 0.00043 19.7 0.0 2.4 2 1 1 3 3 3 1 WD40-like domain DUF5046 PF16465.5 EIM81164.1 - 0.0014 18.1 0.1 0.11 12.0 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) Coatomer_WDAD PF04053.14 EIM81164.1 - 0.033 13.3 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Ge1_WD40 PF16529.5 EIM81164.1 - 0.065 12.2 0.0 0.34 9.8 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LSM PF01423.22 EIM81165.1 - 5.1e-16 58.1 0.1 6.7e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain F-box-like PF12937.7 EIM81166.1 - 8.8e-06 25.5 0.2 8.8e-06 25.5 0.2 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM81166.1 - 0.0072 16.7 2.0 17 6.0 0.0 5.4 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 EIM81169.1 - 1.5e-12 47.1 0.0 1.5e-05 24.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM81169.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Oxidored_FMN PF00724.20 EIM81170.1 - 3.3e-64 217.3 0.0 4.7e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4275 PF14101.6 EIM81170.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) FAD_binding_3 PF01494.19 EIM81171.1 - 4.1e-20 72.3 1.4 1.8e-14 53.8 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 EIM81171.1 - 0.00024 20.3 0.0 0.0006 19.0 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EIM81171.1 - 0.0094 15.2 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM81171.1 - 0.027 15.0 0.1 5 7.8 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM81171.1 - 0.031 13.9 0.3 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM81171.1 - 0.035 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Senescence PF06911.12 EIM81172.1 - 0.18 12.1 0.3 0.27 11.6 0.3 1.2 1 0 0 1 1 1 0 Senescence-associated protein YaiA PF16362.5 EIM81174.1 - 0.0096 16.0 0.1 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 YaiA protein G_glu_transpept PF01019.21 EIM81175.1 - 7.3e-157 523.2 0.0 8.4e-157 523.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3759 PF12585.8 EIM81177.1 - 0.0047 16.9 1.2 0.016 15.2 1.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3759) adh_short PF00106.25 EIM81178.1 - 4e-39 134.1 0.9 1.1e-38 132.6 0.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81178.1 - 5.1e-35 121.1 0.0 9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81178.1 - 2.5e-05 24.3 0.0 4e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM81178.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ApbA PF02558.16 EIM81178.1 - 0.038 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FNIP PF05725.12 EIM81178.1 - 0.09 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 FNIP Repeat YaiA PF16362.5 EIM81179.1 - 0.012 15.6 0.1 0.038 14.1 0.1 1.8 1 0 0 1 1 1 0 YaiA protein DUF563 PF04577.14 EIM81181.1 - 6.3e-18 65.7 0.0 1.8e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Sec63 PF02889.16 EIM81181.1 - 0.24 10.5 0.0 0.6 9.2 0.0 1.6 2 0 0 2 2 2 0 Sec63 Brl domain Palm_thioest PF02089.15 EIM81182.1 - 2.8e-79 266.4 0.0 4.5e-78 262.4 0.0 2.0 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EIM81182.1 - 0.0021 17.7 0.1 0.009 15.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EIM81182.1 - 1.3 8.8 2.5 7.4 6.3 2.5 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3421 PF11901.8 EIM81183.1 - 4e-31 107.4 3.2 2.1e-20 72.8 0.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) ABA_WDS PF02496.16 EIM81183.1 - 0.00016 22.0 2.9 0.00034 21.0 2.9 1.5 1 0 0 1 1 1 1 ABA/WDS induced protein DUF1974 PF09317.11 EIM81183.1 - 0.0045 16.6 0.0 0.0064 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) DUF2076 PF09849.9 EIM81183.1 - 0.21 11.6 2.3 0.12 12.4 0.5 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) p450 PF00067.22 EIM81184.1 - 1.5e-66 225.0 0.0 4.9e-66 223.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 EIM81185.1 - 2.1e-09 37.8 3.3 0.0016 19.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Syncollin PF15138.6 EIM81185.1 - 0.1 12.8 0.1 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 Syncollin CAF1C_H4-bd PF12265.8 EIM81185.1 - 0.11 12.7 0.2 25 5.2 0.1 2.6 2 0 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleos_tra2_C PF07662.13 EIM81186.1 - 1.4e-70 237.4 3.4 1.4e-70 237.4 3.4 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EIM81186.1 - 9.4e-20 71.0 6.5 9.4e-20 71.0 6.5 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EIM81186.1 - 0.013 15.8 8.4 0.013 15.8 8.4 3.0 2 1 0 2 2 2 0 Nucleoside recognition Abhydrolase_3 PF07859.13 EIM81188.1 - 5.2e-26 91.8 0.0 6.7e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM81188.1 - 3.7e-11 42.5 0.0 4.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EIM81188.1 - 0.015 14.8 0.0 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thaumatin PF00314.17 EIM81189.1 - 1.4e-12 47.7 8.8 1.9e-12 47.3 8.8 1.2 1 0 0 1 1 1 1 Thaumatin family Pkinase PF00069.25 EIM81190.1 - 2.6e-66 223.7 0.0 3.1e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81190.1 - 2.3e-40 138.5 0.0 3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM81190.1 - 6.5e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIM81190.1 - 2.4e-05 23.3 0.0 4.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM81190.1 - 0.011 15.6 0.0 0.047 13.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EIM81190.1 - 0.062 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EIM81190.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med1 PF10744.9 EIM81191.1 - 4.2e-06 26.1 0.0 0.0026 16.9 0.0 2.3 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 EIM81192.1 - 2.9e-59 200.6 0.0 4.2e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81192.1 - 2.2e-29 102.6 0.0 3.2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM81192.1 - 4.5e-07 29.5 0.0 1.4e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 EIM81192.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 PH domain APH PF01636.23 EIM81192.1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EIM81192.1 - 0.039 13.6 0.0 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIM81192.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.6 EIM81192.1 - 0.065 13.3 0.1 2.8 8.1 0.0 2.7 2 1 0 2 2 2 0 PH domain ALS_ss_C PF10369.9 EIM81193.1 - 3e-18 65.8 0.9 1.7e-17 63.4 0.1 2.4 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 EIM81193.1 - 4.3e-13 48.8 0.1 7.9e-13 47.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EIM81193.1 - 5.2e-07 29.4 0.1 2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 ACT domain DUF1989 PF09347.10 EIM81195.1 - 9.5e-63 210.8 0.0 1.2e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) COG5 PF10392.9 EIM81196.1 - 3e-27 95.4 0.0 1.1e-26 93.6 0.0 2.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps51 PF08700.11 EIM81196.1 - 0.00082 19.4 0.0 0.014 15.5 0.0 3.2 2 1 0 2 2 2 1 Vps51/Vps67 Baculo_PEP_C PF04513.12 EIM81196.1 - 0.034 14.2 3.0 0.29 11.2 0.2 3.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.14 EIM81196.1 - 0.06 13.2 1.7 0.17 11.7 0.3 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EIM81196.1 - 0.068 12.4 0.1 0.23 10.7 0.1 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex THOC7 PF05615.13 EIM81196.1 - 0.098 12.9 0.0 0.99 9.7 0.0 2.6 1 1 0 1 1 1 0 Tho complex subunit 7 Cellulase PF00150.18 EIM81197.1 - 7.2e-31 107.7 4.6 9.5e-31 107.3 4.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EIM81197.1 - 1.7e-13 50.3 16.2 4.8e-13 48.8 16.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 EIM81197.1 - 0.00088 18.5 0.0 0.0022 17.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_1 PF00232.18 EIM81197.1 - 0.0027 16.2 0.1 0.0053 15.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Peptidase_A22B PF04258.13 EIM81198.1 - 3.1e-76 256.6 0.7 4.1e-76 256.2 0.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EIM81198.1 - 2.8e-05 23.7 4.2 0.00012 21.7 4.2 2.0 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease CrgA PF06781.12 EIM81198.1 - 0.0022 18.0 0.0 0.0094 16.0 0.0 2.0 2 0 0 2 2 2 1 Cell division protein CrgA GATA PF00320.27 EIM81199.1 - 5e-18 64.4 2.7 1e-17 63.5 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EIM81199.1 - 1.9e-11 43.6 1.5 4.7e-11 42.3 1.5 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short PF00106.25 EIM81200.1 - 5.4e-20 71.7 0.0 8.2e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81200.1 - 9e-12 45.0 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PH_9 PF15410.6 EIM81201.1 - 1.5e-27 96.4 0.0 3.4e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 EIM81201.1 - 1e-25 90.5 0.0 2.6e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 EIM81201.1 - 0.00027 21.4 0.0 0.00071 20.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Bundlin PF05307.11 EIM81201.1 - 0.045 13.6 1.0 0.27 11.1 0.1 2.5 2 0 0 2 2 2 0 Bundlin Lzipper-MIP1 PF14389.6 EIM81201.1 - 0.17 12.2 2.1 1 9.7 1.4 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Glyoxalase PF00903.25 EIM81203.1 - 8.5e-21 74.5 0.1 1.2e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EIM81203.1 - 4.2e-05 23.8 0.0 9.4e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EIM81203.1 - 7.5e-05 23.5 0.0 9.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EIM81203.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Glyoxalase-like domain TxDE PF18711.1 EIM81203.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme Methyltransf_22 PF13383.6 EIM81205.1 - 1.7e-20 73.6 0.0 1.2e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_21 PF05050.12 EIM81205.1 - 2.5e-08 34.1 0.0 5.9e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain Arylsulfotran_2 PF14269.6 EIM81206.1 - 1.7e-42 145.9 2.7 1.7e-42 145.9 2.7 1.5 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EIM81206.1 - 1.4e-12 47.2 2.6 5.4e-11 42.0 1.5 2.8 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) Pallilysin PF18663.1 EIM81207.1 - 0.014 15.4 0.0 0.74 9.8 0.0 2.3 2 0 0 2 2 2 0 Pallilysin beta barrel domain TEX13 PF15186.6 EIM81207.1 - 0.022 14.4 3.2 0.66 9.6 0.1 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Apolipoprotein PF01442.18 EIM81207.1 - 4.5 7.1 7.6 5.8 6.7 1.6 2.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DPBB_1 PF03330.18 EIM81208.1 - 0.00047 20.4 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase ChiC PF06483.11 EIM81209.1 - 0.0032 17.4 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Chitinase C NTP_transf_7 PF07984.12 EIM81209.1 - 0.082 12.1 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase ANAPC15 PF15243.6 EIM81209.1 - 2.4 8.6 7.0 0.13 12.7 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 CPSF73-100_C PF11718.8 EIM81211.1 - 3.2e-67 226.2 0.1 4.7e-67 225.7 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EIM81211.1 - 6.6e-31 106.9 0.0 6.7e-30 103.6 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EIM81211.1 - 3.6e-21 75.5 0.0 8e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM81211.1 - 4.5e-18 66.0 1.8 1.7e-17 64.1 0.8 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EIM81211.1 - 7.8e-18 64.2 0.1 2.3e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EIM81211.1 - 6.1e-08 32.4 0.9 1.7e-07 30.9 0.4 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EIM81211.1 - 8.3e-06 25.8 3.2 1.6e-05 24.9 0.3 2.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain CTD_bind PF04818.13 EIM81212.1 - 0.0016 19.2 0.0 0.004 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 EIM81212.1 - 0.0054 17.2 0.1 0.055 14.0 0.1 2.4 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 BIR PF00653.21 EIM81212.1 - 0.042 14.5 0.4 17 6.2 0.0 2.5 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Zn-C2H2_12 PF18112.1 EIM81212.1 - 0.045 14.2 1.5 11 6.6 0.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 EIM81212.1 - 0.21 11.9 0.5 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EIM81212.1 - 0.22 12.4 2.0 6.6 7.9 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Pro_isomerase PF00160.21 EIM81213.1 - 1.4e-47 161.9 0.5 1.8e-47 161.5 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IBR PF01485.21 EIM81214.1 - 7.5e-06 26.1 32.3 1.1e-05 25.5 6.2 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain TERB2 PF15101.6 EIM81214.1 - 6.7 6.7 6.8 54 3.8 2.9 3.2 4 0 0 4 4 4 0 Telomere-associated protein TERB2 Abhydrolase_1 PF00561.20 EIM81215.1 - 9.1e-20 71.4 0.0 3.8e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EIM81215.1 - 1.5e-16 60.4 0.0 3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 EIM81215.1 - 0.062 12.6 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BCDHK_Adom3 PF10436.9 EIM81216.1 - 9.6e-42 142.6 0.0 2.7e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EIM81216.1 - 3e-08 34.1 0.0 8e-06 26.3 0.0 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EIM81216.1 - 0.0081 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAC4 PF16093.5 EIM81218.1 - 9.3e-22 77.0 0.2 1.1e-21 76.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Pkinase PF00069.25 EIM81219.1 - 8.1e-52 176.2 0.0 1.3e-51 175.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81219.1 - 8.7e-23 80.9 0.0 1.3e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM81219.1 - 5.1e-05 23.3 0.0 9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM81219.1 - 0.00041 20.0 0.1 0.00094 18.8 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EIM81219.1 - 0.012 15.2 0.2 0.028 14.0 0.1 1.7 2 1 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EIM81219.1 - 0.1 11.9 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LAG1-DNAbind PF09271.11 EIM81224.1 - 1.8e-49 168.2 0.0 3.4e-49 167.3 0.0 1.5 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 EIM81224.1 - 6e-20 72.0 0.0 4.7e-18 65.9 0.0 2.6 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain MOZ_SAS PF01853.18 EIM81225.1 - 2.2e-79 265.3 0.7 3e-79 264.8 0.7 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EIM81225.1 - 4.2e-22 77.5 0.9 1e-21 76.3 0.9 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EIM81225.1 - 3.1e-18 65.4 0.0 6e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EIM81225.1 - 0.0085 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_Mga PF08280.11 EIM81225.1 - 0.085 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain zf-C2H2_4 PF13894.6 EIM81225.1 - 0.41 11.6 5.4 0.28 12.1 1.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.32 EIM81226.1 - 5.2e-17 61.9 6.8 1.1e-07 32.4 0.1 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat zf-GRF PF06839.12 EIM81226.1 - 1.4e-08 34.7 2.1 3.7e-08 33.3 2.1 1.8 1 0 0 1 1 1 1 GRF zinc finger ANAPC4_WD40 PF12894.7 EIM81226.1 - 1.2e-06 28.7 0.1 0.67 10.3 0.0 5.1 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain C2 PF00168.30 EIM81226.1 - 2.8e-06 27.6 0.0 6.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain AAA_16 PF13191.6 EIM81226.1 - 0.0007 20.0 1.2 0.0062 16.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EIM81226.1 - 0.0022 18.0 0.0 0.0069 16.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EIM81226.1 - 0.0036 16.3 0.0 0.024 13.6 0.0 2.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 EIM81226.1 - 0.029 14.3 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat AAA_22 PF13401.6 EIM81226.1 - 0.073 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EIM81226.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein SURF6 PF04935.12 EIM81226.1 - 3.1 7.5 6.7 6.1 6.6 6.7 1.4 1 0 0 1 1 1 0 Surfeit locus protein 6 ERO1 PF04137.15 EIM81228.1 - 4.6e-129 430.6 0.0 5.6e-129 430.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) KH_1 PF00013.29 EIM81229.1 - 2.7e-86 283.4 35.5 1.2e-13 50.7 0.4 13.6 13 1 0 13 13 13 10 KH domain KH_2 PF07650.17 EIM81229.1 - 1.5e-09 37.5 17.6 0.072 12.9 0.1 7.5 7 1 0 8 8 8 4 KH domain SLS PF14611.6 EIM81229.1 - 0.00021 21.2 13.8 0.29 10.9 0.1 6.7 5 4 2 7 7 7 2 Mitochondrial inner-membrane-bound regulator DUF4974 PF16344.5 EIM81229.1 - 0.00048 20.1 1.5 0.03 14.3 0.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4974) KH_4 PF13083.6 EIM81229.1 - 0.002 18.0 14.0 12 5.9 0.0 8.2 8 0 0 8 8 8 1 KH domain TrkA_C PF02080.21 EIM81229.1 - 0.073 12.9 0.5 40 4.1 0.1 4.1 4 0 0 4 4 4 0 TrkA-C domain KH_5 PF13184.6 EIM81229.1 - 4 7.6 17.2 7.8 6.7 1.3 6.6 7 1 0 7 7 7 0 NusA-like KH domain TMEM208_SND2 PF05620.11 EIM81230.1 - 0.52 10.1 14.0 0.81 9.4 2.6 3.1 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 RRM_1 PF00076.22 EIM81231.1 - 5.2e-10 39.0 0.0 0.00043 20.0 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 EIM81231.1 - 6e-10 39.0 0.2 1.5e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 Surp module RSRP PF17069.5 EIM81231.1 - 0.012 15.2 54.5 0.039 13.5 54.5 1.9 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CTD_bind PF04818.13 EIM81231.1 - 0.019 15.8 0.0 0.045 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRM_7 PF16367.5 EIM81231.1 - 0.13 12.3 0.0 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif Scs3p PF10261.9 EIM81232.1 - 3.3e-46 157.8 1.0 2.8e-37 128.6 0.0 2.3 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM WD40 PF00400.32 EIM81233.1 - 4.8e-15 55.7 7.7 1.4e-06 28.9 0.1 6.9 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM81233.1 - 3.7e-06 27.1 0.0 3.8 7.9 0.0 5.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain C2 PF00168.30 EIM81233.1 - 1.7e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain AAA_16 PF13191.6 EIM81233.1 - 0.00043 20.7 0.1 0.0019 18.6 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EIM81233.1 - 0.00078 19.4 0.1 0.0033 17.3 0.0 2.2 2 1 0 2 2 2 1 NACHT domain PD40 PF07676.12 EIM81233.1 - 0.026 14.4 0.0 5.6 7.0 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EIM81233.1 - 0.028 13.4 0.0 0.13 11.2 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TniB PF05621.11 EIM81233.1 - 0.065 12.6 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein ATP-sulfurylase PF01747.17 EIM81234.1 - 1.5e-87 292.5 0.2 2.1e-87 292.0 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EIM81234.1 - 2.1e-51 173.7 0.0 3.3e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 EIM81234.1 - 3.4e-47 160.3 0.0 5.2e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EIM81234.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIM81234.1 - 0.006 16.1 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 EIM81234.1 - 0.007 16.2 0.2 0.081 12.8 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 EIM81234.1 - 0.11 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 EIM81235.1 - 2.2e-47 161.7 0.1 6.4e-47 160.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EIM81235.1 - 1e-25 89.6 0.3 2.5e-25 88.4 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 EIM81235.1 - 3.2e-18 66.2 0.0 8.7e-18 64.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain 2-Hacid_dh_C PF02826.19 EIM81236.1 - 1.9e-45 154.4 0.0 2.7e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM81236.1 - 2e-19 69.6 0.0 2.5e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIM81236.1 - 2.1e-05 24.7 0.0 5.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EIM81236.1 - 0.016 15.3 0.0 0.049 13.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Bromodomain PF00439.25 EIM81237.1 - 1.6e-22 79.3 0.1 5.8e-22 77.6 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Acetyltransf_10 PF13673.7 EIM81237.1 - 3.9e-06 26.8 0.2 8.4e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM81237.1 - 4.8e-06 26.8 0.1 8.9e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM81237.1 - 0.00043 20.7 0.4 0.00082 19.7 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM81237.1 - 0.12 12.4 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein GFO_IDH_MocA PF01408.22 EIM81239.1 - 1e-17 65.1 0.0 1.6e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIM81239.1 - 0.04 14.6 0.0 0.06 14.0 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CDKN3 PF05706.12 EIM81240.1 - 3.3e-05 23.6 0.1 5.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 EIM81240.1 - 4.9e-05 23.2 0.2 9.1e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EIM81240.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EIM81240.1 - 0.58 9.7 1.1 1.1 8.8 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Chitin_synth_2 PF03142.15 EIM81241.1 - 1.4e-250 832.4 0.0 1.7e-250 832.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EIM81241.1 - 1.1e-14 54.9 0.2 1.6e-13 51.1 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EIM81241.1 - 1.1e-13 51.6 7.0 1.1e-13 51.6 7.0 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EIM81241.1 - 0.0012 18.3 0.1 0.034 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF1080 PF06439.11 EIM81242.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) NmrA PF05368.13 EIM81244.1 - 7.1e-27 94.5 0.0 9.8e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM81244.1 - 9.5e-10 38.7 0.0 7.1e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM81244.1 - 0.003 17.8 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 EIM81244.1 - 0.063 13.9 0.0 1.8 9.2 0.0 2.5 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EIM81244.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SBP_bac_8 PF13416.6 EIM81244.1 - 0.13 12.0 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein RhoGAP PF00620.27 EIM81244.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain Beta-lactamase PF00144.24 EIM81245.1 - 8.7e-37 127.1 2.3 1.3e-36 126.5 2.3 1.2 1 0 0 1 1 1 1 Beta-lactamase GFO_IDH_MocA PF01408.22 EIM81246.1 - 5.8e-16 59.4 0.0 9.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIM81246.1 - 0.0082 16.8 0.2 0.013 16.1 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Tmemb_9 PF05434.11 EIM81248.1 - 0.39 10.6 6.9 0.15 12.0 3.1 1.9 1 1 1 2 2 2 0 TMEM9 SNARE PF05739.19 EIM81249.1 - 9e-05 22.4 0.5 0.00024 21.0 0.0 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EIM81249.1 - 0.00015 21.5 0.5 0.00028 20.6 0.5 1.5 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 EIM81249.1 - 0.011 16.0 1.2 2.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Syntaxin-like protein HAUS-augmin3 PF14932.6 EIM81249.1 - 0.16 11.5 8.3 0.12 12.0 5.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 EIM81249.1 - 0.44 9.9 5.8 0.58 9.5 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_membrane PF00664.23 EIM81250.1 - 5.9e-45 154.0 26.9 7.5e-26 91.4 7.8 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 EIM81250.1 - 1.8e-35 122.4 0.1 4.3e-26 92.1 0.1 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM81250.1 - 2e-08 34.0 5.6 0.17 11.3 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIM81250.1 - 2.5e-06 27.2 0.1 0.04 13.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EIM81250.1 - 3.1e-06 27.2 2.5 0.024 14.4 0.1 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIM81250.1 - 1.2e-05 25.9 1.4 0.011 16.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIM81250.1 - 1.9e-05 25.1 0.3 0.36 11.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EIM81250.1 - 2.1e-05 24.2 1.2 0.15 11.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EIM81250.1 - 8.3e-05 22.1 0.1 0.25 10.7 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SSE PF00437.20 EIM81250.1 - 0.00014 21.0 0.0 0.04 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 EIM81250.1 - 0.00029 20.4 0.2 0.79 9.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EIM81250.1 - 0.00044 20.3 0.5 0.28 11.3 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 EIM81250.1 - 0.00061 19.9 3.6 0.0062 16.7 0.3 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EIM81250.1 - 0.0042 17.0 0.4 1.6 8.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 EIM81250.1 - 0.0044 16.8 1.0 2 8.1 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein Dynamin_N PF00350.23 EIM81250.1 - 0.0058 16.7 0.8 0.28 11.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 EIM81250.1 - 0.0089 16.3 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 EIM81250.1 - 0.017 14.0 0.1 0.49 9.1 0.0 2.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 EIM81250.1 - 0.022 14.7 0.6 14 5.7 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EIM81250.1 - 0.028 14.8 0.1 2.1 8.8 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EIM81250.1 - 0.052 13.3 0.5 13 5.5 0.1 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_15 PF13175.6 EIM81250.1 - 0.062 13.0 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EIM81250.1 - 0.084 11.8 1.5 1.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EIM81250.1 - 0.087 12.5 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EIM81250.1 - 0.21 11.3 0.0 0.61 9.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain PLDc_N PF13396.6 EIM81250.1 - 0.25 11.3 7.1 0.12 12.4 3.0 2.7 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal cobW PF02492.19 EIM81250.1 - 0.28 10.8 3.2 0.84 9.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 EIM81250.1 - 0.31 10.5 1.4 20 4.5 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.12 EIM81250.1 - 0.72 9.8 2.7 5.6 6.9 0.1 3.0 3 0 0 3 3 3 0 NACHT domain Cpn60_TCP1 PF00118.24 EIM81251.1 - 1.6e-162 541.6 0.6 2.1e-162 541.2 0.6 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-LYAR PF08790.11 EIM81252.1 - 2.3e-15 56.2 2.5 5e-15 55.1 2.5 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EIM81252.1 - 2.4 9.2 5.8 14 6.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Na_H_Exchanger PF00999.21 EIM81253.1 - 6.8e-57 193.0 22.9 7.9e-57 192.8 22.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1345 PF07077.11 EIM81253.1 - 0.075 12.7 1.4 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) UPF0182 PF03699.13 EIM81253.1 - 4.2 5.4 4.4 3.2 5.8 3.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) FAD_binding_3 PF01494.19 EIM81254.1 - 1.1e-25 90.7 0.0 1.9e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM81254.1 - 1.7e-05 24.2 0.1 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM81254.1 - 0.00075 19.2 0.3 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 EIM81254.1 - 0.006 15.7 0.0 0.03 13.4 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EIM81254.1 - 0.014 15.6 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EIM81254.1 - 0.034 14.7 0.2 11 6.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EIM81254.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L11_N PF03946.14 EIM81255.1 - 2.5e-23 81.7 0.2 3.9e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EIM81255.1 - 5.1e-19 68.5 0.4 8.9e-19 67.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyclin PF08613.11 EIM81256.1 - 4.9e-27 95.3 0.6 4.9e-27 95.3 0.6 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EIM81256.1 - 4.8e-06 26.3 0.2 7.6e-06 25.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2500 PF10694.9 EIM81257.1 - 0.29 11.7 2.2 0.45 11.0 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Pkinase PF00069.25 EIM81258.1 - 1.3e-33 116.5 0.0 2.4e-31 109.1 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81258.1 - 4.6e-19 68.7 0.0 8.8e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM81258.1 - 0.14 11.5 0.0 0.38 10.0 0.0 1.7 1 1 0 1 1 1 0 Kinase-like U3_assoc_6 PF08640.11 EIM81259.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 THAP PF05485.12 EIM81259.1 - 0.12 13.3 0.0 0.17 12.8 0.0 1.3 1 0 0 1 1 1 0 THAP domain Cwf_Cwc_15 PF04889.12 EIM81260.1 - 0.001 18.8 3.2 0.0022 17.8 3.2 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SART-1 PF03343.13 EIM81260.1 - 0.024 13.2 1.5 0.029 12.9 1.5 1.1 1 0 0 1 1 1 0 SART-1 family SDA1 PF05285.12 EIM81260.1 - 0.03 13.8 1.2 0.042 13.3 1.2 1.3 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EIM81260.1 - 0.58 9.4 3.5 0.87 8.9 3.5 1.2 1 0 0 1 1 1 0 NOA36 protein Got1 PF04178.12 EIM81261.1 - 9.3e-19 67.9 13.8 1.2e-18 67.5 13.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family F-box-like PF12937.7 EIM81262.1 - 1.1e-08 34.9 0.3 3e-08 33.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81262.1 - 0.0042 16.9 1.5 0.62 10.0 0.3 2.9 2 0 0 2 2 2 2 F-box domain BRO1 PF03097.18 EIM81263.1 - 3.2e-21 75.6 0.0 4.3e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain Paramyxo_ncap PF00973.19 EIM81264.1 - 7.4 5.4 20.5 10 4.9 19.6 1.7 1 1 0 1 1 1 0 Paramyxovirus nucleocapsid protein PI3_PI4_kinase PF00454.27 EIM81265.1 - 2.6e-38 132.3 0.0 4.7e-38 131.4 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Voltage_CLC PF00654.20 EIM81266.1 - 1.1e-90 304.5 30.8 1.6e-90 303.9 30.8 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EIM81266.1 - 4.1e-12 46.4 0.3 0.00011 22.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain Autophagy_N PF03986.13 EIM81267.1 - 2.2e-42 144.2 0.1 6.2e-42 142.8 0.0 1.9 2 1 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EIM81267.1 - 6.7e-17 61.8 0.2 1.3e-16 60.9 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EIM81267.1 - 1.3e-12 47.0 2.9 2.5e-12 46.1 2.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CHZ PF09649.10 EIM81269.1 - 5.2e-11 41.8 0.1 5.2e-11 41.8 0.1 2.5 2 1 0 2 2 2 1 Histone chaperone domain CHZ FAM176 PF14851.6 EIM81269.1 - 0.23 11.1 10.8 0.046 13.4 7.4 1.6 1 1 1 2 2 2 0 FAM176 family CDC27 PF09507.10 EIM81269.1 - 0.45 9.8 12.5 0.54 9.6 12.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RPN2_C PF18004.1 EIM81269.1 - 3.5 7.5 11.7 0.8 9.6 8.2 1.6 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 EIM81269.1 - 3.8 5.5 24.1 3.9 5.4 24.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi F-box PF00646.33 EIM81270.1 - 0.054 13.4 0.2 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 F-box domain DUF3756 PF12581.8 EIM81270.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) LRR_4 PF12799.7 EIM81270.1 - 0.4 11.2 6.6 32 5.1 0.8 5.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Methyltransf_25 PF13649.6 EIM81271.1 - 6.7e-13 49.2 0.0 1.9e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIM81271.1 - 5e-11 42.5 0.0 8.2e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EIM81271.1 - 6.2e-11 42.3 0.0 1.3e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM81271.1 - 5.8e-10 39.7 0.0 1.8e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM81271.1 - 2.1e-08 34.2 0.0 9.4e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EIM81271.1 - 3.9e-07 29.3 0.0 5.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EIM81271.1 - 1.1e-06 28.2 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EIM81271.1 - 4.3e-06 27.4 0.0 8.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM81271.1 - 4.6e-06 26.3 0.1 7.5e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EIM81271.1 - 0.00029 20.6 0.1 0.00054 19.8 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EIM81271.1 - 0.00037 20.5 0.1 0.00077 19.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EIM81271.1 - 0.001 18.5 0.2 0.0026 17.2 0.2 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 EIM81271.1 - 0.0023 18.1 0.0 0.005 17.0 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EIM81271.1 - 0.0025 17.8 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM81271.1 - 0.0038 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EIM81271.1 - 0.008 15.9 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EIM81271.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Cons_hypoth95 PF03602.15 EIM81271.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 EIM81271.1 - 0.078 12.4 0.2 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.6 EIM81271.1 - 0.14 13.2 0.0 0.33 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2367 PF10164.9 EIM81272.1 - 3.2e-08 34.0 4.4 5.6e-08 33.2 4.4 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) CAP_N PF01213.19 EIM81272.1 - 2.3 7.6 5.2 2.4 7.6 5.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal bZIP_1 PF00170.21 EIM81275.1 - 5.3e-10 39.3 10.6 6.9e-10 38.9 6.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EIM81275.1 - 1.4e-09 37.9 12.4 2.4e-09 37.1 4.6 2.3 2 0 0 2 2 2 2 Basic region leucine zipper ABC_tran_CTD PF16326.5 EIM81275.1 - 0.0081 16.4 5.0 0.014 15.7 5.0 1.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain TSC22 PF01166.18 EIM81275.1 - 0.012 15.9 1.0 0.053 13.8 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Mto2_bdg PF12808.7 EIM81275.1 - 0.031 14.6 1.7 0.031 14.6 1.7 2.5 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Fmp27_WPPW PF10359.9 EIM81275.1 - 0.05 12.5 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain bZIP_Maf PF03131.17 EIM81275.1 - 0.31 11.6 10.1 0.15 12.6 7.4 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 EIM81275.1 - 0.77 9.6 5.4 7.8 6.4 0.8 2.3 1 1 1 2 2 2 0 Septum formation initiator VanZ PF04892.12 EIM81276.1 - 3e-06 27.9 2.8 5.6e-06 27.0 2.8 1.4 1 1 0 1 1 1 1 VanZ like family MnhB PF04039.13 EIM81276.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.1 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter RraA-like PF03737.15 EIM81277.1 - 9.6e-34 116.7 0.0 1.2e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Peptidase_C14 PF00656.22 EIM81278.1 - 7.7e-19 68.6 0.0 1.4e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Fungal_trans PF04082.18 EIM81279.1 - 1.4e-24 86.6 0.5 1.4e-24 86.6 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM81279.1 - 2.5e-08 33.9 10.6 4.6e-08 33.0 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EIM81280.1 - 1.4e-10 40.9 6.5 2.3e-10 40.2 6.5 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIM81280.1 - 0.49 10.0 4.1 0.83 9.3 4.1 1.3 1 0 0 1 1 1 0 PHD-finger DUF4890 PF16231.5 EIM81280.1 - 0.77 10.3 3.6 0.33 11.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) PHD_4 PF16866.5 EIM81280.1 - 2.2 8.5 5.2 6 7.0 5.2 1.8 1 0 0 1 1 1 0 PHD-finger PALP PF00291.25 EIM81281.1 - 1.3e-77 261.1 0.6 2e-77 260.5 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EIM81281.1 - 1.6e-42 143.2 0.0 1.4e-24 85.7 0.0 2.5 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HU-HIG PF18291.1 EIM81281.1 - 0.15 12.1 0.0 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif APG6 PF04111.12 EIM81284.1 - 8.5e-71 237.6 0.0 1.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EIM81284.1 - 1.5e-28 99.9 23.4 2.4e-28 99.3 23.4 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Rpr2 PF04032.16 EIM81284.1 - 0.067 13.5 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain V_ATPase_I PF01496.19 EIM81284.1 - 0.88 7.4 4.0 1.2 7.0 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3072 PF11272.8 EIM81284.1 - 1.7 8.6 4.8 0.32 10.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) MMS1_N PF10433.9 EIM81285.1 - 1.8e-161 538.1 0.0 2.8e-161 537.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EIM81285.1 - 1.3e-93 313.9 0.0 1.2e-92 310.7 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region IMS PF00817.20 EIM81286.1 - 3.8e-44 150.3 0.0 9.3e-44 149.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EIM81286.1 - 2.5e-15 57.2 0.1 9.5e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EIM81286.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 EIM81286.1 - 0.0055 16.4 0.8 0.014 15.0 0.1 2.0 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 Phosducin PF02114.16 EIM81286.1 - 0.13 11.2 0.1 7.9 5.3 0.0 2.5 2 0 0 2 2 2 0 Phosducin UspB PF10625.9 EIM81286.1 - 0.22 11.5 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein B (UspB) GST_C PF00043.25 EIM81288.1 - 1.9e-12 47.2 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM81288.1 - 4.2e-09 36.6 0.0 8.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM81288.1 - 1.6e-07 31.4 0.0 3.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIM81288.1 - 1e-06 29.1 0.0 1.8e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81288.1 - 1.2e-06 28.7 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM81288.1 - 3e-06 27.2 0.6 7e-06 26.0 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain MPC PF03650.13 EIM81289.1 - 3.9e-40 136.4 0.5 4.3e-40 136.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Apq12 PF12716.7 EIM81290.1 - 0.048 13.6 1.4 0.048 13.6 1.4 1.8 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis RPA_interact_C PF14768.6 EIM81291.1 - 0.008 16.7 0.6 0.014 16.0 0.6 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Sugar_tr PF00083.24 EIM81292.1 - 2e-92 310.4 15.0 2.4e-92 310.2 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM81292.1 - 1.5e-18 66.9 26.9 1.5e-18 66.9 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 EIM81292.1 - 0.39 10.9 3.9 0.64 10.3 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) peroxidase PF00141.23 EIM81294.1 - 3.2e-44 151.3 0.0 5.4e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4184 PF13803.6 EIM81295.1 - 0.0055 16.4 1.2 0.0085 15.8 1.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4184) Med3 PF11593.8 EIM81296.1 - 0.0096 15.2 13.2 0.012 14.9 13.2 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal CLLAC PF15675.5 EIM81296.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain AP3D1 PF06375.11 EIM81296.1 - 0.71 10.1 4.5 1 9.6 4.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 IBR PF01485.21 EIM81296.1 - 1.2 9.4 5.1 0.18 12.1 0.6 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Hid1 PF12722.7 EIM81296.1 - 6.3 4.8 7.0 7 4.6 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Aminotran_3 PF00202.21 EIM81297.1 - 8.6e-119 396.8 0.0 1.1e-118 396.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EIM81297.1 - 0.0043 16.3 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II zf-ANAPC11 PF12861.7 EIM81297.1 - 0.058 13.4 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Beta_elim_lyase PF01212.21 EIM81297.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase zf-RING_2 PF13639.6 EIM81298.1 - 1.8e-11 44.2 4.7 3e-11 43.5 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EIM81298.1 - 8.1e-07 28.7 1.7 8.1e-07 28.7 1.7 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EIM81298.1 - 3.2e-06 26.9 4.6 5.5e-06 26.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM81298.1 - 3e-05 24.2 4.6 9e-05 22.7 4.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EIM81298.1 - 4.2e-05 23.5 1.6 7.9e-05 22.6 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EIM81298.1 - 0.00011 21.9 3.3 0.00018 21.2 3.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EIM81298.1 - 0.00013 21.8 2.7 0.00022 21.0 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM81298.1 - 0.00049 20.0 2.4 0.00084 19.3 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 EIM81298.1 - 0.0034 17.5 1.6 0.0091 16.1 1.6 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EIM81298.1 - 0.0091 15.8 1.3 0.016 15.1 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EIM81298.1 - 0.015 15.4 2.3 0.031 14.4 2.3 1.6 1 0 0 1 1 1 0 RING-variant domain UBZ_FAAP20 PF15750.5 EIM81298.1 - 0.021 14.8 2.0 0.36 10.8 0.5 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Prok-RING_4 PF14447.6 EIM81298.1 - 0.03 14.2 6.5 0.25 11.3 7.0 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EIM81298.1 - 0.067 13.2 4.1 0.94 9.6 0.9 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.6 EIM81298.1 - 0.13 12.2 4.5 0.76 9.7 1.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Glyco_transf_18 PF15024.6 EIM81299.1 - 3e-13 49.2 0.0 4.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glutaredoxin PF00462.24 EIM81300.1 - 1.8e-10 40.9 0.0 4.5e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin HAD_2 PF13419.6 EIM81301.1 - 9.6e-16 58.4 0.0 1.9e-15 57.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM81301.1 - 2.7e-08 34.4 0.0 6e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EIM81301.1 - 0.0092 16.1 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EIM81301.1 - 0.01 16.3 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM81301.1 - 0.11 12.6 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like DUF3328 PF11807.8 EIM81302.1 - 0.016 15.0 0.2 0.025 14.4 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) ATG22 PF11700.8 EIM81302.1 - 0.24 10.0 0.2 0.34 9.5 0.2 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like adh_short PF00106.25 EIM81303.1 - 3.3e-13 49.6 0.3 1.1e-09 38.0 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81303.1 - 6.6e-12 45.5 0.1 2.8e-11 43.4 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.28 EIM81306.1 - 2.4e-43 148.3 0.0 3.2e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EIM81306.1 - 8.4e-05 22.4 0.2 0.00018 21.3 0.2 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EIM81306.1 - 0.022 15.7 0.0 0.082 13.9 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RHD3 PF05879.12 EIM81307.1 - 7.2e-247 821.3 0.5 1.5e-246 820.2 0.5 1.5 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EIM81307.1 - 4.3e-07 29.4 1.0 1e-06 28.2 0.3 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EIM81307.1 - 2.3e-06 27.7 0.1 9.4e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EIM81307.1 - 3e-05 24.1 0.0 7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EIM81307.1 - 0.002 18.4 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain LLC1 PF14945.6 EIM81307.1 - 0.082 13.5 0.8 0.18 12.4 0.8 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Septin PF00735.18 EIM81307.1 - 0.093 12.0 0.1 0.28 10.4 0.1 1.8 1 0 0 1 1 1 0 Septin Roc PF08477.13 EIM81307.1 - 0.14 12.4 0.5 0.55 10.5 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BAR PF03114.18 EIM81308.1 - 1.3e-51 175.6 3.2 1.5e-51 175.4 3.2 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EIM81308.1 - 0.00031 20.5 0.2 0.00055 19.7 0.2 1.5 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 EIM81308.1 - 0.0006 19.5 3.2 0.33 10.5 0.2 2.1 2 0 0 2 2 2 2 Arfaptin-like domain Laminin_I PF06008.14 EIM81308.1 - 0.051 13.3 0.8 0.11 12.1 0.1 1.9 3 0 0 3 3 3 0 Laminin Domain I GldM_N PF12081.8 EIM81308.1 - 0.059 13.5 2.0 1.3 9.1 0.6 2.2 2 0 0 2 2 2 0 GldM N-terminal domain DUF4164 PF13747.6 EIM81308.1 - 0.22 11.8 4.1 2.6 8.4 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Adaptin_binding PF10199.9 EIM81310.1 - 0.087 13.4 1.2 0.15 12.7 0.2 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Cwf_Cwc_15 PF04889.12 EIM81310.1 - 0.85 9.3 9.7 0.042 13.6 1.8 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 EIM81310.1 - 5.1 7.5 10.1 3.6 8.0 1.1 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EIM81310.1 - 6.4 7.2 16.7 0.96 9.9 2.0 3.6 4 0 0 4 4 4 0 Centromere protein B dimerisation domain NDUF_B12 PF08122.12 EIM81311.1 - 3.3e-19 68.7 4.4 5.1e-19 68.1 4.4 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Topoisom_I PF01028.20 EIM81312.1 - 1e-100 335.8 5.3 3.1e-100 334.2 5.3 1.9 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EIM81312.1 - 8.6e-95 316.3 0.2 8.6e-95 316.3 0.2 3.7 4 2 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EIM81312.1 - 3.7e-38 129.3 0.8 1.4e-37 127.5 0.8 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Cep57_MT_bd PF06657.13 EIM81312.1 - 0.01 16.3 0.1 0.01 16.3 0.1 3.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TetR_C_23 PF17931.1 EIM81312.1 - 0.062 13.4 0.0 0.062 13.4 0.0 3.5 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain CTP_transf_1 PF01148.20 EIM81313.1 - 7e-72 242.4 20.3 9.2e-72 242.0 20.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CbtA PF09490.10 EIM81313.1 - 0.47 10.2 0.0 0.47 10.2 0.0 3.0 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtA) COX7C PF02935.16 EIM81313.1 - 3.2 8.1 9.4 0.11 12.7 0.7 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Ribosom_S12_S23 PF00164.25 EIM81314.1 - 2.3e-49 165.8 0.8 2.8e-49 165.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Abhydrolase_1 PF00561.20 EIM81315.1 - 8.2e-12 45.3 0.0 4.2e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM81315.1 - 6.2e-05 23.7 0.1 8e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM81315.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CsbD PF05532.12 EIM81316.1 - 2.3e-14 53.0 12.7 7.2e-08 32.2 2.6 2.0 1 1 1 2 2 2 2 CsbD-like F-box PF00646.33 EIM81317.1 - 4.2e-07 29.7 0.3 1.5e-06 27.9 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM81317.1 - 3.7e-06 26.7 0.0 1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like Ig_mannosidase PF17753.1 EIM81318.1 - 2.8e-10 39.8 0.0 7.5e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 EIM81318.1 - 4e-09 37.0 2.1 1.2e-08 35.4 2.1 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EIM81318.1 - 0.07 13.8 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Acyltransferase PF01553.21 EIM81319.1 - 3.7e-16 59.0 0.0 6.7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase MNHE PF01899.16 EIM81319.1 - 0.26 11.0 3.1 0.66 9.7 3.1 1.6 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit SPC22 PF04573.12 EIM81320.1 - 4.4e-50 169.5 0.0 5e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit LRR_8 PF13855.6 EIM81322.1 - 4.4e-47 157.7 54.9 3.1e-14 52.5 1.6 11.7 6 3 8 15 15 15 11 Leucine rich repeat PP2C PF00481.21 EIM81322.1 - 4.9e-45 154.2 0.0 8.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 EIM81322.1 - 7.4e-45 150.2 62.6 2.7e-06 27.6 0.9 13.4 4 3 14 19 19 19 17 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EIM81322.1 - 6.4e-24 84.6 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_6 PF13516.6 EIM81322.1 - 6.2e-06 25.9 55.7 0.02 14.9 0.5 14.6 16 1 1 17 17 17 4 Leucine Rich repeat LRR_9 PF14580.6 EIM81322.1 - 7.5e-06 25.6 19.7 0.055 13.0 0.1 5.9 2 2 5 7 7 7 3 Leucine-rich repeat LRR_1 PF00560.33 EIM81322.1 - 1.6e-05 24.8 43.2 6.6 7.7 0.2 14.7 16 0 0 16 16 16 2 Leucine Rich Repeat LRR_5 PF13306.6 EIM81322.1 - 0.00019 21.4 0.3 4.3 7.3 0.0 4.0 4 0 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) Mg_trans_NIPA PF05653.14 EIM81323.1 - 7e-80 268.3 30.9 9.3e-80 267.9 30.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EIM81323.1 - 3.1e-07 30.6 8.4 3.1e-07 30.6 8.4 3.7 2 2 1 3 3 3 2 EamA-like transporter family Med7 PF05983.11 EIM81324.1 - 0.087 12.9 0.7 0.13 12.4 0.7 1.6 1 1 0 1 1 1 0 MED7 protein Toxin_trans PF07952.12 EIM81324.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain TIG PF01833.24 EIM81325.1 - 5e-10 39.3 0.5 1.9e-09 37.4 0.2 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 EIM81325.1 - 3.2e-09 37.3 0.0 6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM81325.1 - 1.2e-06 28.7 0.3 0.0018 18.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EIM81325.1 - 1.7e-06 28.2 0.0 0.0034 17.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EIM81325.1 - 0.0014 18.9 0.0 2.7 8.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EIM81325.1 - 0.0023 18.4 0.0 0.014 16.0 0.0 2.4 1 1 2 3 3 3 1 Ankyrin repeats (many copies) NUP50 PF08911.11 EIM81326.1 - 3.6e-16 59.6 0.2 3.6e-16 59.6 0.2 7.1 7 1 0 7 7 7 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 EIM81326.1 - 4.7e-13 49.5 0.1 8.9e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain RabGAP-TBC PF00566.18 EIM81327.1 - 1.1e-52 178.9 0.0 1.4e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 EIM81327.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Interleukin 34 CxC6 PF18721.1 EIM81329.1 - 8.2 6.8 7.0 22 5.4 0.4 2.6 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Hist_deacetyl PF00850.19 EIM81330.1 - 2.2e-58 198.1 0.0 3.1e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ILVD_EDD PF00920.21 EIM81331.1 - 1.3e-197 657.5 0.0 1.5e-197 657.3 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DUF5127 PF17168.4 EIM81332.1 - 3.5e-81 272.3 7.3 5.9e-81 271.6 7.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM81332.1 - 3.1e-76 254.9 1.1 1.9e-75 252.3 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM81332.1 - 3.3e-63 213.1 3.1 1e-62 211.5 3.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM81332.1 - 1.5e-09 37.3 0.0 5.5e-09 35.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) VID27_PH PF17747.1 EIM81332.1 - 0.031 14.6 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 VID27 PH-like domain ETF PF01012.21 EIM81333.1 - 5.2e-36 124.2 0.4 9.5e-36 123.4 0.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EIM81333.1 - 2.9e-32 110.5 0.6 5.9e-32 109.5 0.6 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain TPR_1 PF00515.28 EIM81334.1 - 2.8e-15 55.4 0.0 0.00019 21.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM81334.1 - 2.8e-14 52.0 5.6 0.00063 19.7 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM81334.1 - 4.2e-11 43.3 8.2 3.6e-06 27.5 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM81334.1 - 4.3e-10 39.0 1.0 0.11 12.8 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIM81334.1 - 9.1e-09 35.4 7.2 0.011 16.5 0.0 6.3 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIM81334.1 - 9e-07 28.5 0.0 1.7 8.9 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EIM81334.1 - 2.6e-06 27.6 7.2 0.012 15.9 0.2 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIM81334.1 - 1e-05 25.1 0.3 0.018 14.7 0.0 3.4 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 EIM81334.1 - 3.6e-05 23.9 1.1 0.54 10.8 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIM81334.1 - 0.00058 19.6 3.5 0.59 10.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIM81334.1 - 0.0059 15.9 1.6 0.052 12.8 0.1 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM81334.1 - 0.017 15.6 0.0 0.27 11.8 0.0 5.3 4 1 3 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EIM81334.1 - 0.047 13.8 2.6 0.72 10.0 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Leukocidin PF07968.12 EIM81334.1 - 0.17 11.8 0.2 0.34 10.8 0.2 1.4 1 0 0 1 1 1 0 Leukocidin/Hemolysin toxin family TPR_20 PF14561.6 EIM81334.1 - 0.27 11.6 4.7 0.74 10.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM81334.1 - 0.87 10.4 5.0 41 5.1 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat OPT PF03169.15 EIM81335.1 - 3.3e-127 425.7 36.3 3.7e-127 425.5 36.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Lipase_3 PF01764.25 EIM81337.1 - 0.0074 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EIM81337.1 - 0.046 14.3 4.1 0.09 13.4 4.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3450 PF11932.8 EIM81338.1 - 0.23 10.7 0.3 0.4 9.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Serglycin PF04360.12 EIM81339.1 - 0.044 13.7 0.4 0.044 13.7 0.4 2.2 2 0 0 2 2 2 0 Serglycin Hydrolase_4 PF12146.8 EIM81341.1 - 1.1e-06 28.1 0.0 0.0089 15.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM81341.1 - 0.0025 18.5 0.3 0.0025 18.5 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EIM81341.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 EIM81341.1 - 0.21 11.4 0.1 0.39 10.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Herpes_U47 PF05467.11 EIM81341.1 - 7.4 4.6 5.6 12 3.8 5.6 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 ATG7_N PF16420.5 EIM81342.1 - 5.3e-85 285.7 0.0 8.7e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EIM81342.1 - 2.9e-45 154.5 0.0 4.3e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family ELFV_dehydrog PF00208.21 EIM81342.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 EIM81342.1 - 0.23 11.5 0.0 0.59 10.2 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4449 PF14613.6 EIM81343.1 - 1.1e-11 45.1 0.0 1.1e-11 45.1 0.0 4.0 3 2 1 4 4 4 1 Protein of unknown function (DUF4449) KxDL PF10241.9 EIM81343.1 - 0.002 18.4 0.7 0.042 14.1 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein HisKA_3 PF07730.13 EIM81343.1 - 0.12 12.9 2.1 16 6.1 0.0 3.9 3 0 0 3 3 3 0 Histidine kinase Inhibitor_I34 PF10466.9 EIM81343.1 - 5.7 7.6 12.5 6.1 7.5 0.1 3.7 3 0 0 3 3 3 0 Saccharopepsin inhibitor I34 DUF349 PF03993.12 EIM81343.1 - 8.3 6.8 8.2 2.8 8.3 1.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) GST_N_2 PF13409.6 EIM81344.1 - 4.9e-10 39.6 0.8 1.1e-09 38.5 0.5 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM81344.1 - 7.4e-10 39.1 0.2 2.2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain UPF0506 PF11703.8 EIM81344.1 - 0.13 12.7 3.4 0.23 11.9 3.4 1.3 1 0 0 1 1 1 0 UPF0506 Conotoxin_I2 PF17557.2 EIM81344.1 - 0.18 11.9 5.9 0.32 11.2 5.9 1.4 1 0 0 1 1 1 0 I2-superfamily conotoxins G3P_acyltransf PF02660.15 EIM81348.1 - 0.13 12.3 5.0 0.22 11.6 5.0 1.4 1 1 0 1 1 1 0 Glycerol-3-phosphate acyltransferase GST_N_3 PF13417.6 EIM81349.1 - 2.7e-10 40.5 0.1 8.6e-10 38.9 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81349.1 - 1.2e-07 31.9 0.1 5e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain PAS_4 PF08448.10 EIM81349.1 - 0.0031 17.8 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold GST_C_2 PF13410.6 EIM81349.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GTP_CH_N PF12471.8 EIM81351.1 - 8.4e-87 289.9 0.0 1.2e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EIM81351.1 - 2.5e-14 53.2 0.0 4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Peptidase_A4 PF01828.17 EIM81352.1 - 2e-41 141.8 6.7 2.4e-41 141.5 6.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family Tyrosinase PF00264.20 EIM81353.1 - 4.1e-52 177.7 3.3 4.1e-52 177.7 3.3 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EIM81353.1 - 3.8e-32 111.5 0.0 7e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain Sugar_tr PF00083.24 EIM81354.1 - 1.4e-20 73.6 18.4 1.9e-16 60.0 1.8 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EIM81354.1 - 4.5e-18 65.3 47.8 3.9e-12 45.8 25.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GH131_N PF18271.1 EIM81355.1 - 1.1e-65 221.9 0.7 1.4e-65 221.6 0.7 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain F-box-like PF12937.7 EIM81356.1 - 7.8e-05 22.5 0.2 0.00022 21.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like BTB PF00651.31 EIM81357.1 - 6.9e-08 32.7 0.0 2.7e-07 30.8 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain Ribonuclease_3 PF00636.26 EIM81358.1 - 4.9e-42 142.8 0.0 1.6e-22 80.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIM81358.1 - 9.3e-27 93.7 0.5 6.3e-09 36.1 0.0 4.6 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.14 EIM81358.1 - 8.2e-20 70.8 0.0 2.9e-19 69.0 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 EIM81358.1 - 2.1e-14 53.7 0.0 4.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM81358.1 - 2.4e-14 53.6 0.0 8.6e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM81358.1 - 4.1e-13 49.7 0.0 8.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NAD_binding_4 PF07993.12 EIM81359.1 - 1.5e-32 112.8 0.0 2.6e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM81359.1 - 9e-30 103.6 0.0 3.5e-29 101.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM81359.1 - 2.6e-05 23.8 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF468 PF04318.12 EIM81359.1 - 0.092 13.5 0.2 0.26 12.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF468) PP-binding PF00550.25 EIM81359.1 - 0.098 13.0 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site GST_N_3 PF13417.6 EIM81360.1 - 1.9e-12 47.4 0.3 5.1e-12 46.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81360.1 - 3.3e-09 36.9 0.3 1.4e-08 34.9 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM81360.1 - 0.00022 21.2 0.3 0.00065 19.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM81360.1 - 0.00055 20.1 0.1 0.0015 18.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain APH PF01636.23 EIM81361.1 - 1.4e-18 67.7 0.3 2.7e-18 66.8 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM81361.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase GST_N_3 PF13417.6 EIM81362.1 - 6e-12 45.8 0.1 1.3e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81362.1 - 1.4e-10 41.3 0.3 1.2e-09 38.3 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM81362.1 - 0.0038 17.4 0.0 0.0074 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_4 PF08448.10 EIM81362.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold GST_C_2 PF13410.6 EIM81362.1 - 0.025 14.6 0.1 0.052 13.6 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAS PF00989.25 EIM81362.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 PAS fold Cu-oxidase PF00394.22 EIM81363.1 - 2.9e-39 134.8 1.1 1.8e-38 132.2 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM81363.1 - 2e-31 108.5 1.5 5.9e-31 107.0 1.0 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM81363.1 - 3.8e-31 107.6 2.8 1.5e-26 92.7 0.0 3.5 3 1 0 3 3 3 3 Multicopper oxidase OATP PF03137.20 EIM81365.1 - 0.0031 15.9 1.7 0.0031 15.9 1.7 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family YrhK PF14145.6 EIM81365.1 - 6.2 6.8 37.1 1.4 8.9 0.7 5.3 4 1 1 5 5 5 0 YrhK-like protein DRMBL PF07522.14 EIM81366.1 - 7.7e-06 26.1 0.0 3.5e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EIM81366.1 - 0.0041 16.7 1.5 0.019 14.5 0.2 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain F-box-like PF12937.7 EIM81367.1 - 0.00049 19.9 0.2 0.0016 18.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM81368.1 - 0.00098 19.0 0.1 0.0033 17.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM81368.1 - 2.4 8.7 12.2 14 6.3 0.1 5.2 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EIM81369.1 - 0.00019 21.2 0.8 0.00019 21.2 0.8 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EIM81370.1 - 0.00023 21.0 0.2 0.00071 19.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like Ribonuc_red_lgC PF02867.15 EIM81371.1 - 8.5e-182 605.3 0.0 1.2e-181 604.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EIM81371.1 - 3e-24 84.8 0.1 1.1e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EIM81371.1 - 1e-16 61.3 1.7 1.1e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain F-box-like PF12937.7 EIM81372.1 - 2.6e-05 24.0 0.1 6.6e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF4200 PF13863.6 EIM81372.1 - 0.061 13.7 0.5 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) GNAT_acetyltr_2 PF13718.6 EIM81373.1 - 3e-89 298.3 0.0 5.5e-89 297.5 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EIM81373.1 - 1.5e-83 280.1 0.0 2.5e-83 279.4 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EIM81373.1 - 5.6e-65 218.5 0.0 2.7e-64 216.3 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EIM81373.1 - 1.8e-32 111.1 0.0 4.3e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EIM81373.1 - 9.1e-05 22.3 0.0 0.028 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EIM81373.1 - 0.016 15.5 0.0 0.34 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain BTB PF00651.31 EIM81374.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 EIM81375.1 - 4e-06 26.6 0.3 1.9e-05 24.4 0.3 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM81376.1 - 1.2e-06 28.3 0.1 1.2e-06 28.3 0.1 2.8 3 0 0 3 3 3 1 F-box-like Methyltransf_23 PF13489.6 EIM81378.1 - 3.1e-15 56.4 0.0 4.8e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM81378.1 - 1.9e-13 50.5 0.0 1.8e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM81378.1 - 9.7e-11 42.2 0.0 2.2e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM81378.1 - 2.4e-10 40.9 0.0 4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM81378.1 - 1.9e-08 35.0 0.0 6.9e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM81378.1 - 6.8e-06 25.7 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EIM81378.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EIM81378.1 - 4.6e-05 23.0 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EIM81378.1 - 0.00021 21.4 0.0 0.00031 20.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EIM81378.1 - 0.00034 20.0 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 EIM81378.1 - 0.0045 16.5 0.0 0.027 14.0 0.0 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 EIM81378.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 EIM81378.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_18 PF12847.7 EIM81378.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EIM81378.1 - 0.032 13.5 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 EIM81378.1 - 0.069 12.9 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 EIM81379.1 - 1.1e-15 57.9 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM81379.1 - 2.2e-12 47.0 0.0 2.1e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM81379.1 - 1.4e-10 41.8 0.0 5.6e-10 39.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM81379.1 - 9e-10 39.1 0.0 1.8e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM81379.1 - 7e-09 36.3 0.0 3.8e-08 34.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EIM81379.1 - 3.3e-05 23.7 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF938 PF06080.12 EIM81379.1 - 6.2e-05 22.9 0.0 9.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 EIM81379.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EIM81379.1 - 0.0006 19.4 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EIM81379.1 - 0.00078 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EIM81379.1 - 0.00092 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EIM81379.1 - 0.0023 18.1 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EIM81379.1 - 0.0036 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 EIM81379.1 - 0.0091 15.5 0.0 0.029 13.9 0.0 1.7 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 EIM81379.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Sugar_tr PF00083.24 EIM81380.1 - 8.3e-33 113.9 21.6 1.2e-32 113.3 21.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM81380.1 - 3e-32 111.9 31.1 3e-32 111.9 31.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81381.1 - 5.9e-113 378.1 21.8 6.9e-113 377.9 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM81381.1 - 1.4e-21 76.8 39.3 1.6e-14 53.6 10.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 EIM81382.1 - 7.8e-50 169.6 0.1 1.1e-49 169.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM81382.1 - 2.7e-41 141.2 0.1 3.4e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM81382.1 - 4e-14 52.9 0.1 5.8e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM81382.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3277 PF11681.8 EIM81382.1 - 0.0042 17.0 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) GDP_Man_Dehyd PF16363.5 EIM81382.1 - 0.005 16.3 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM81382.1 - 0.016 14.2 0.0 0.035 13.1 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Transketolase_N PF00456.21 EIM81383.1 - 1.3e-126 422.1 0.0 1.9e-126 421.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EIM81383.1 - 2.2e-40 138.3 0.0 3.4e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIM81383.1 - 2.8e-07 30.4 0.0 7.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EIM81383.1 - 2e-06 27.2 0.0 0.00015 21.1 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EIM81383.1 - 4.9e-06 26.4 0.4 5.2e-05 23.1 0.5 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.16 EIM81384.1 - 1.4e-34 119.6 32.4 1.4e-34 119.6 32.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81384.1 - 1.1e-30 106.9 21.1 1.7e-29 103.0 22.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter UPF0227 PF05728.12 EIM81384.1 - 0.2 11.6 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Bac_surface_Ag PF01103.23 EIM81386.1 - 3.5e-36 125.3 0.0 4.3e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 EIM81386.1 - 0.006 17.1 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Surface antigen variable number repeat IBN_N PF03810.19 EIM81386.1 - 0.2 11.6 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain Ebp2 PF05890.12 EIM81388.1 - 4e-85 285.6 1.2 7.1e-85 284.8 1.2 1.4 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 SDA1 PF05285.12 EIM81388.1 - 0.088 12.2 41.8 0.38 10.1 41.8 1.9 1 1 0 1 1 1 0 SDA1 U1snRNP70_N PF12220.8 EIM81388.1 - 7.4 7.3 10.1 0.67 10.6 4.5 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PRP1_N PF06424.12 EIM81389.1 - 5.3e-49 166.4 3.7 5.3e-49 166.4 3.7 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EIM81389.1 - 9.3e-22 75.9 32.7 0.0035 18.0 0.2 13.7 5 4 9 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 EIM81389.1 - 1.1e-16 61.1 7.1 0.015 15.8 0.2 7.8 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 EIM81389.1 - 1.1e-10 42.0 8.0 0.00042 20.9 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EIM81389.1 - 4.8e-05 23.7 1.8 0.99 10.2 0.1 6.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM81389.1 - 0.0052 17.1 0.5 2.1 8.7 0.1 4.6 2 1 2 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 EIM81389.1 - 0.025 14.6 0.0 6.8 6.6 0.0 3.8 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_11 PF13414.6 EIM81389.1 - 0.032 13.9 0.3 0.41 10.4 0.1 2.9 3 0 0 3 3 3 0 TPR repeat DUF919 PF06034.11 EIM81391.1 - 0.035 14.0 0.8 0.058 13.2 0.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PSS PF03034.15 EIM81393.1 - 1.6e-114 382.3 13.4 2.1e-114 381.9 13.4 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase Actin PF00022.19 EIM81394.1 - 1.3e-75 254.5 0.0 1.2e-74 251.4 0.0 1.9 1 1 0 1 1 1 1 Actin TANGO2 PF05742.12 EIM81395.1 - 3.3e-46 158.4 0.0 3.9e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Zn_clus PF00172.18 EIM81397.1 - 1.9e-09 37.5 7.1 3.1e-09 36.8 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBN_N PF03810.19 EIM81399.1 - 2.7e-09 36.8 0.0 3.2e-06 27.0 0.0 2.7 2 0 0 2 2 2 2 Importin-beta N-terminal domain Cnd1 PF12717.7 EIM81399.1 - 0.0017 18.4 0.3 0.0079 16.3 0.3 2.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EIM81399.1 - 0.0062 16.7 0.1 0.034 14.3 0.1 2.4 1 1 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EIM81399.1 - 0.0073 16.7 1.0 0.12 12.8 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats DUF913 PF06025.12 EIM81399.1 - 0.05 12.6 0.1 0.099 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cnd3 PF12719.7 EIM81399.1 - 0.068 12.3 0.3 0.21 10.8 0.3 1.8 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Cse1 PF08506.10 EIM81399.1 - 0.071 11.9 0.0 0.16 10.8 0.0 1.6 1 0 0 1 1 1 0 Cse1 HEAT_EZ PF13513.6 EIM81399.1 - 0.072 13.6 0.6 20 5.8 0.1 4.8 4 0 0 4 4 4 0 HEAT-like repeat MIF4G_like PF09088.11 EIM81399.1 - 0.096 12.4 0.0 0.89 9.3 0.0 2.3 1 1 0 2 2 2 0 MIF4G like API5 PF05918.11 EIM81399.1 - 0.36 9.6 4.3 6.2 5.5 0.8 2.7 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) HEAT PF02985.22 EIM81399.1 - 0.55 10.6 6.6 0.38 11.1 0.1 4.4 6 0 0 6 6 5 0 HEAT repeat F-box-like PF12937.7 EIM81401.1 - 1e-07 31.7 0.6 2.7e-07 30.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81401.1 - 0.00014 21.6 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain MscS_TM PF12794.7 EIM81402.1 - 0.0035 16.3 1.7 0.02 13.8 1.7 1.9 1 1 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 Peptidase_S28 PF05577.12 EIM81403.1 - 7.1e-54 183.2 0.0 8.9e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Tombus_P33 PF08500.10 EIM81404.1 - 3.3 7.7 4.8 28 4.7 0.0 2.6 2 1 0 2 2 2 0 Tombusvirus p33 TAF PF02969.17 EIM81406.1 - 5.9e-27 93.6 0.4 3.3e-26 91.2 0.2 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EIM81406.1 - 2.4e-14 53.4 0.0 6.4e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 EIM81406.1 - 0.00043 20.6 0.2 0.0012 19.2 0.2 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EIM81406.1 - 0.00093 19.3 0.7 0.0021 18.1 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit DUF1918 PF08940.11 EIM81406.1 - 0.0023 17.5 0.0 0.0094 15.6 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1918) Bromo_TP PF07524.13 EIM81406.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated Chitin_bind_4 PF00379.23 EIM81408.1 - 0.039 14.5 0.6 0.083 13.4 0.2 1.9 2 1 0 2 2 2 0 Insect cuticle protein Melibiase_2 PF16499.5 EIM81409.1 - 8.8e-62 208.8 3.1 1.4e-61 208.1 3.1 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EIM81409.1 - 3.2e-17 62.4 0.1 1.2e-14 54.2 0.0 2.5 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EIM81409.1 - 0.0027 16.7 0.1 0.0051 15.8 0.1 1.4 1 0 0 1 1 1 1 Melibiase Amidase PF01425.21 EIM81410.1 - 1.7e-82 277.8 0.0 2.2e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Kinesin PF00225.23 EIM81411.1 - 4.5e-92 308.5 0.0 9.1e-92 307.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIM81411.1 - 9.3e-22 77.6 0.0 2.9e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 EIM81411.1 - 0.085 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein MscS_porin PF12795.7 EIM81411.1 - 0.1 12.1 13.1 2.6 7.6 6.4 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Pox_A_type_inc PF04508.12 EIM81411.1 - 0.34 10.8 7.4 0.062 13.2 2.5 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PfkB PF00294.24 EIM81412.1 - 1.4e-09 37.7 0.0 3.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Na_H_Exchanger PF00999.21 EIM81413.1 - 7.3e-65 219.2 23.5 8.9e-65 218.9 23.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ApoLp-III PF07464.11 EIM81413.1 - 0.092 12.8 0.3 2.8 8.0 0.3 2.1 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Kin17_mid PF10357.9 EIM81414.1 - 9.8e-50 167.7 0.7 9.8e-50 167.7 0.7 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EIM81414.1 - 0.0012 19.1 4.8 0.003 17.9 4.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EIM81414.1 - 0.021 15.2 3.8 0.034 14.5 0.4 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EIM81414.1 - 0.037 14.3 3.6 0.037 14.3 3.6 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding F-box PF00646.33 EIM81415.1 - 0.0074 16.1 0.2 0.021 14.7 0.2 1.8 1 0 0 1 1 1 1 F-box domain ArfGap PF01412.18 EIM81415.1 - 0.026 14.6 3.2 0.098 12.7 3.2 2.0 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf F-box_4 PF15966.5 EIM81415.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 F-box GATA PF00320.27 EIM81415.1 - 0.29 10.8 5.3 0.8 9.4 5.3 1.8 1 0 0 1 1 1 0 GATA zinc finger LOR PF04525.12 EIM81416.1 - 2.4e-30 105.5 0.0 2.9e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related NmrA PF05368.13 EIM81417.1 - 1.3e-29 103.4 0.0 1.6e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM81417.1 - 4.4e-13 49.5 0.0 7.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM81417.1 - 7.9e-07 29.4 0.1 1.3e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EIM81417.1 - 0.00043 19.4 0.1 0.00064 18.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.16 EIM81417.1 - 0.00061 19.5 0.2 0.00094 18.8 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 EIM81417.1 - 0.003 17.1 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 EIM81417.1 - 0.036 14.3 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_3 PF03447.16 EIM81417.1 - 0.038 14.6 0.3 9.9 6.9 0.1 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EIM81417.1 - 0.098 11.9 0.6 0.19 11.0 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amidase PF01425.21 EIM81418.1 - 7.4e-81 272.4 0.1 9.6e-81 272.0 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF2407_C PF13373.6 EIM81419.1 - 2.7e-23 82.7 4.1 2.7e-20 73.0 0.2 2.5 1 1 1 2 2 2 2 DUF2407 C-terminal domain DUF2407 PF10302.9 EIM81419.1 - 1.1e-15 58.1 0.0 2.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EIM81419.1 - 0.0035 17.0 0.1 0.0085 15.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family VIT1 PF01988.19 EIM81419.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 VIT family Pkinase_fungal PF17667.1 EIM81420.1 - 2.4e-36 125.4 0.0 3.4e-23 82.1 0.0 2.6 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 EIM81420.1 - 1.2e-06 28.7 0.4 2.6e-06 27.5 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM81420.1 - 1.6e-06 27.7 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EIM81420.1 - 0.00055 19.0 0.0 0.00086 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EIM81420.1 - 0.0035 17.0 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EIM81420.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase HetR_C PF18460.1 EIM81421.1 - 0.13 12.2 0.1 15 5.6 0.0 2.7 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Furin-like_2 PF15913.5 EIM81423.1 - 0.00032 20.8 3.2 0.00097 19.3 2.3 2.2 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich F-box PF00646.33 EIM81423.1 - 0.0024 17.7 0.2 0.0073 16.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain SURF2 PF05477.11 EIM81423.1 - 0.0071 16.1 5.1 0.011 15.4 5.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) F-box_4 PF15966.5 EIM81423.1 - 0.053 13.4 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 EIM81423.1 - 0.066 13.1 0.2 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 F-box-like SPT6_acidic PF14632.6 EIM81423.1 - 0.13 12.8 5.3 0.33 11.6 5.3 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 BUD22 PF09073.10 EIM81423.1 - 0.38 10.0 10.8 0.56 9.5 10.8 1.1 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.6 EIM81423.1 - 0.63 10.4 7.7 2.2 8.7 7.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 EIM81423.1 - 1.6 6.9 3.9 2.3 6.4 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.33 EIM81424.1 - 0.00014 21.6 0.6 0.00048 19.9 0.6 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM81424.1 - 0.066 13.1 0.2 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 EIM81424.1 - 0.083 12.8 0.2 0.24 11.3 0.2 1.8 1 0 0 1 1 1 0 F-box BTB PF00651.31 EIM81425.1 - 2.1e-06 27.9 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1932 PF09130.11 EIM81426.1 - 1.3e-15 57.2 0.0 4.7e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 EIM81426.1 - 1.9e-07 31.4 0.0 4.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EIM81426.1 - 2.3e-05 24.0 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EIM81426.1 - 0.0015 19.0 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EIM81426.1 - 0.0036 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EIM81426.1 - 0.039 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2884 PF11101.8 EIM81426.1 - 0.18 11.3 0.1 0.81 9.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Methyltransf_31 PF13847.6 EIM81428.1 - 9.8e-10 38.4 0.0 4.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EIM81428.1 - 1.1e-08 35.7 0.0 7.3e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM81428.1 - 9e-08 32.8 0.0 4.7e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM81428.1 - 6e-07 30.0 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM81428.1 - 1.1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EIM81428.1 - 0.00061 18.5 0.0 0.00083 18.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 EIM81428.1 - 0.042 13.3 0.0 0.099 12.1 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain ADD_DNMT3 PF17980.1 EIM81429.1 - 0.021 14.8 1.6 0.15 12.1 0.3 2.9 3 0 0 3 3 3 0 Cysteine rich ADD domain in DNMT3 Gin PF10764.9 EIM81429.1 - 0.12 12.3 0.8 0.86 9.6 0.1 2.5 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin DZR PF12773.7 EIM81429.1 - 1.2 9.2 5.3 1.8 8.7 0.3 3.1 3 0 0 3 3 3 0 Double zinc ribbon F-box-like PF12937.7 EIM81430.1 - 0.012 15.5 0.1 0.049 13.5 0.0 2.1 2 0 0 2 2 2 0 F-box-like zinc_ribbon_10 PF10058.9 EIM81430.1 - 4.7 7.0 13.1 5.7 6.8 2.2 3.5 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Asp PF00026.23 EIM81431.1 - 1.2e-48 166.2 18.9 3.5e-48 164.6 18.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM81431.1 - 2.3e-09 37.8 9.1 1.2e-05 25.6 0.5 3.4 1 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM81431.1 - 0.0016 19.1 5.7 0.029 15.0 0.9 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EIM81431.1 - 0.007 16.9 2.5 0.081 13.5 0.2 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EIM81431.1 - 0.033 14.0 0.1 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase_fungal PF17667.1 EIM81433.1 - 4.1e-06 25.8 0.0 6.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase IBR PF01485.21 EIM81434.1 - 0.041 14.1 17.2 1 9.6 0.5 3.6 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Yippee-Mis18 PF03226.14 EIM81434.1 - 0.84 9.9 5.9 1.8 8.8 0.1 3.2 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly eIF-5_eIF-2B PF01873.17 EIM81434.1 - 0.88 9.5 4.3 32 4.4 0.2 3.2 3 0 0 3 3 3 0 Domain found in IF2B/IF5 HATPase_c PF02518.26 EIM81435.1 - 8.4e-49 164.8 0.2 4.1e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM81435.1 - 6.4e-46 155.1 1.0 3.2e-26 91.7 0.1 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EIM81435.1 - 9.5e-19 67.2 2.1 1.9e-11 43.8 0.1 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EIM81435.1 - 4.4e-06 26.9 0.0 0.062 13.5 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EIM81435.1 - 0.00019 21.4 0.0 0.00072 19.5 0.0 2.0 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 EIM81435.1 - 0.0049 16.7 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 EIM81435.1 - 2.2 8.5 3.5 26 5.0 0.0 2.7 2 1 1 3 3 3 0 PAS fold Glyco_hydro_35 PF01301.19 EIM81437.1 - 3.9e-79 266.6 0.1 6.3e-79 265.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EIM81437.1 - 7.7e-55 184.4 8.5 5.9e-33 113.8 0.1 3.6 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EIM81437.1 - 2e-39 135.3 5.4 3.5e-39 134.5 5.4 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EIM81437.1 - 2.2e-18 65.6 0.9 1.2e-17 63.3 0.3 2.5 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 EIM81437.1 - 2e-05 24.1 0.3 0.00028 20.4 0.3 2.3 1 1 1 2 2 2 1 Beta-galactosidase Amidohydro_2 PF04909.14 EIM81437.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Orthopox_A36R PF05950.11 EIM81437.1 - 0.1 12.8 0.5 0.31 11.2 0.2 1.9 2 0 0 2 2 2 0 Orthopoxvirus A36R protein ABM PF03992.16 EIM81438.1 - 8.5e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PP2C PF00481.21 EIM81439.1 - 4.4e-25 88.8 0.0 1.2e-22 80.8 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EIM81439.1 - 8e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EIM81439.1 - 0.00083 19.3 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Glyco_hydro_35 PF01301.19 EIM81441.1 - 1.1e-69 235.5 0.1 3.3e-69 233.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EIM81441.1 - 1.2e-50 170.9 0.9 1.7e-29 102.7 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EIM81441.1 - 4.7e-23 81.9 0.1 7.3e-22 78.0 0.0 2.5 1 1 1 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EIM81441.1 - 7.6e-13 47.8 0.0 1.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 EthD PF07110.11 EIM81442.1 - 1.5e-14 54.9 0.0 1.8e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 EthD domain DUF2750 PF11042.8 EIM81442.1 - 0.095 12.8 0.1 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2750) CAP_GLY PF01302.25 EIM81442.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 CAP-Gly domain RNA_pol_Rpb2_6 PF00562.28 EIM81443.1 - 0.099 11.7 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Epimerase PF01370.21 EIM81446.1 - 6.5e-15 55.3 0.0 3e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM81446.1 - 4e-12 45.7 0.0 6.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM81446.1 - 1.3e-09 37.9 0.0 1.6e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM81446.1 - 1.6e-06 27.5 0.0 5e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EIM81446.1 - 0.0013 18.2 0.0 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM81446.1 - 0.0033 16.6 0.0 0.017 14.2 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EIM81446.1 - 0.027 14.0 0.0 0.25 10.8 0.0 2.2 2 1 0 2 2 2 0 NmrA-like family RRM_1 PF00076.22 EIM81447.1 - 1.2e-07 31.4 0.1 0.0019 18.0 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 EIM81448.1 - 5e-83 279.4 26.5 6.3e-83 279.1 26.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM81448.1 - 6.5e-43 147.0 49.2 1e-31 110.2 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EthD PF07110.11 EIM81449.1 - 1.5e-08 35.6 0.0 2e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EIM81449.1 - 0.023 15.1 0.0 0.043 14.3 0.0 1.4 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Glyco_hydro_35 PF01301.19 EIM81450.1 - 1e-77 261.9 0.1 1.5e-77 261.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EIM81450.1 - 1.2e-54 183.7 7.8 3.8e-31 108.0 0.2 4.3 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EIM81450.1 - 2.6e-38 131.6 5.7 5.2e-38 130.7 5.7 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EIM81450.1 - 3e-21 74.8 0.6 7.8e-20 70.2 0.2 2.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Sec23_BS PF08033.12 EIM81450.1 - 0.05 14.3 0.5 1.3 9.8 0.2 2.6 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain Amidohydro_2 PF04909.14 EIM81450.1 - 0.16 11.7 0.1 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase zf-MYND PF01753.18 EIM81451.1 - 1.4e-05 25.1 8.4 3.4e-05 23.8 8.4 1.7 1 0 0 1 1 1 1 MYND finger DUF2500 PF10694.9 EIM81451.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Abhydrolase_3 PF07859.13 EIM81452.1 - 1.2e-63 214.8 0.0 1.5e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM81452.1 - 7.6e-08 31.7 0.2 3e-07 29.7 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EIM81452.1 - 8.8e-06 26.5 0.0 1.3e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EIM81452.1 - 0.00081 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EIM81452.1 - 0.0019 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Say1_Mug180 PF10340.9 EIM81452.1 - 0.0062 15.4 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EIM81452.1 - 0.043 13.3 0.0 0.74 9.2 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF1187 PF06688.11 EIM81452.1 - 0.16 12.3 0.4 0.37 11.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1187) FAD_binding_4 PF01565.23 EIM81453.1 - 2.8e-19 69.2 0.2 5.1e-19 68.4 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM81453.1 - 3.7e-09 36.5 0.0 9.9e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_43 PF04616.14 EIM81457.1 - 7.2e-11 41.9 6.6 1.3e-10 41.1 6.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pyrid_ox_like PF16242.5 EIM81457.1 - 0.052 13.1 0.1 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like DUF2457 PF10446.9 EIM81458.1 - 0.022 13.9 0.8 0.034 13.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase_fungal PF17667.1 EIM81459.1 - 4.5e-12 45.5 0.0 1.8e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase DUF3328 PF11807.8 EIM81461.1 - 4.6e-12 46.2 0.6 1.5e-11 44.5 0.3 1.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) But2 PF09792.9 EIM81462.1 - 3.7e-06 27.4 0.0 6.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 EIM81464.1 - 2.6e-15 56.8 11.5 3.1e-14 53.3 11.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.25 EIM81465.1 - 0.00058 20.1 0.0 0.00081 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM81465.1 - 0.0019 18.6 0.0 0.0046 17.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM81465.1 - 0.0022 17.9 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM81465.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM81465.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein UPF0669 PF17065.5 EIM81465.1 - 0.044 13.6 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 Hist_deacetyl PF00850.19 EIM81466.1 - 2.3e-52 178.4 0.0 3.3e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain XPG_N PF00752.17 EIM81467.1 - 2.4e-33 114.6 0.0 5.9e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EIM81467.1 - 1e-29 102.7 0.4 5.4e-29 100.4 0.0 2.4 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EIM81467.1 - 1.1e-07 32.3 0.1 2.8e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EIM81467.1 - 0.02 15.5 0.0 0.058 14.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Na_trans_assoc PF06512.13 EIM81467.1 - 1.1 9.5 26.8 0.51 10.6 23.9 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated DUF2868 PF11067.8 EIM81467.1 - 4.4 6.7 6.1 5.9 6.3 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Ndc1_Nup PF09531.10 EIM81467.1 - 6.3 5.4 8.8 8.8 4.9 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Abhydrolase_3 PF07859.13 EIM81468.1 - 5.8e-28 98.2 0.0 1.2e-27 97.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM81468.1 - 0.00021 20.3 0.0 0.036 12.9 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase 4HBT_3 PF13622.6 EIM81469.1 - 2.7e-30 106.4 4.5 4.4e-30 105.8 4.5 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EIM81469.1 - 0.017 15.4 1.2 0.75 10.2 0.3 3.2 3 1 0 3 3 3 0 Thioesterase superfamily p450 PF00067.22 EIM81470.1 - 1.1e-62 212.3 0.0 1.3e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM81471.1 - 2.9e-64 217.5 0.0 3.3e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MrpF_PhaF PF04066.13 EIM81471.1 - 0.11 12.9 0.5 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) zf-CCHC PF00098.23 EIM81472.1 - 5.8e-10 38.8 7.0 0.00018 21.5 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EIM81472.1 - 0.0024 17.6 6.2 0.36 10.7 1.2 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EIM81472.1 - 0.0046 16.9 0.4 0.37 10.8 0.1 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIM81472.1 - 0.02 14.7 2.7 0.02 14.7 2.7 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-BED PF02892.15 EIM81472.1 - 0.031 14.3 2.2 0.69 10.0 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-CCHC_4 PF14392.6 EIM81472.1 - 0.069 12.9 7.3 0.96 9.2 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle Gelsolin PF00626.22 EIM81473.1 - 2.1e-33 114.1 0.0 5.8e-15 55.0 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Methyltransf_33 PF10017.9 EIM81474.1 - 8.8e-71 238.6 0.0 1.3e-40 139.5 0.0 2.1 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EIM81474.1 - 6.1e-18 65.3 1.6 1.8e-09 37.6 0.1 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EIM81474.1 - 1.9e-06 28.4 0.1 3.9e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 DinB superfamily DEAD PF00270.29 EIM81475.1 - 1.3e-17 64.2 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM81475.1 - 6.9e-13 48.9 0.0 3.2e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM81475.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EIM81475.1 - 0.083 12.9 0.0 8.2 6.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain Tetraspanin PF00335.20 EIM81477.1 - 0.051 13.3 0.1 5 6.8 0.2 2.2 2 0 0 2 2 2 0 Tetraspanin family Peroxidase_ext PF11895.8 EIM81478.1 - 4.2e-25 87.5 2.3 1e-24 86.2 2.3 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 EIM81478.1 - 1.9e-23 83.4 0.7 2.9e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Peroxidase Putative_PNPOx PF01243.20 EIM81479.1 - 0.00084 19.5 0.0 0.59 10.4 0.0 2.9 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 EIM81479.1 - 0.0076 16.9 0.0 0.023 15.3 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EIM81479.1 - 0.032 14.4 0.0 0.13 12.4 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain PDE4_UCR PF18100.1 EIM81479.1 - 0.037 14.7 0.0 0.071 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Glyco_hydro_92 PF07971.12 EIM81480.1 - 6.9e-133 443.9 0.1 9.6e-133 443.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EIM81480.1 - 1.6e-54 185.4 2.8 2.3e-54 184.8 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain F-box-like PF12937.7 EIM81481.1 - 5.8e-09 35.7 0.0 2.5e-08 33.7 0.0 2.2 2 1 0 2 2 2 1 F-box-like zf-C2H2 PF00096.26 EIM81483.1 - 8.3e-13 48.0 8.8 3e-06 27.4 1.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM81483.1 - 3.8e-09 36.6 15.6 5.4e-07 29.8 2.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM81483.1 - 4.6e-08 33.3 7.4 0.0016 19.1 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EIM81483.1 - 6.9e-05 23.4 0.4 0.022 15.4 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EIM81483.1 - 0.0022 18.1 0.7 0.69 10.0 0.0 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 EIM81483.1 - 0.027 14.8 0.3 0.035 14.4 0.3 1.3 1 1 0 1 1 1 0 C2H2-type zinc ribbon RPAP2_Rtr1 PF04181.13 EIM81483.1 - 0.039 14.3 0.4 1.5 9.2 0.1 2.0 1 1 1 2 2 2 0 Rtr1/RPAP2 family zf-C2H2_6 PF13912.6 EIM81483.1 - 0.11 12.6 1.9 1.8 8.7 0.0 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EIM81483.1 - 0.39 10.5 13.3 1.7 8.5 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain F-box-like PF12937.7 EIM81485.1 - 6.8e-11 41.9 0.0 2.9e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81485.1 - 0.93 9.4 7.3 7.7 6.5 0.2 3.6 3 0 0 3 3 3 0 F-box domain Terpene_synth_C PF03936.16 EIM81486.1 - 2.2e-07 30.5 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 EIM81486.1 - 0.0011 18.0 0.1 0.0019 17.2 0.1 1.3 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Peroxidase_ext PF11895.8 EIM81487.1 - 3.1e-27 94.3 0.7 6.5e-27 93.3 0.7 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 EIM81487.1 - 9.3e-24 84.4 0.0 1.6e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Peroxidase WD40 PF00400.32 EIM81489.1 - 5.6e-10 39.6 3.1 0.0052 17.6 0.1 5.2 4 0 0 4 4 4 4 WD domain, G-beta repeat DHHC PF01529.20 EIM81490.1 - 2.6e-31 108.5 3.6 2.6e-31 108.5 3.6 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase SPX PF03105.19 EIM81490.1 - 0.0028 17.6 1.0 0.015 15.3 1.1 1.9 2 0 0 2 2 2 1 SPX domain Avl9 PF09794.9 EIM81491.1 - 4.5e-129 430.4 0.0 5.8e-129 430.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EIM81491.1 - 1.2e-07 31.6 6.5 0.00059 19.5 0.5 2.8 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EIM81491.1 - 8.2e-06 25.8 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Med3 PF11593.8 EIM81491.1 - 1.5 7.9 5.7 4.2 6.5 5.7 1.7 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.7 EIM81492.1 - 1.6e-06 27.9 3.7 4.3e-06 26.5 3.7 1.8 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.6 EIM81493.1 - 4.6e-10 39.7 6.9 0.058 13.7 0.2 5.2 3 1 0 4 4 4 3 Tetratricopeptide repeat AAA_22 PF13401.6 EIM81493.1 - 2.9e-06 27.6 0.0 1.1e-05 25.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain SNAP PF14938.6 EIM81493.1 - 7.5e-06 25.6 0.4 0.0047 16.4 0.2 2.5 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP NB-ARC PF00931.22 EIM81493.1 - 0.00011 21.5 0.0 0.00026 20.3 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EIM81493.1 - 0.00013 21.9 0.1 0.00029 20.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EIM81493.1 - 0.00013 22.4 1.4 0.0077 16.6 0.0 3.7 2 2 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 EIM81493.1 - 0.0036 17.8 0.0 0.0076 16.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 EIM81493.1 - 0.0072 16.1 0.0 0.05 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EIM81493.1 - 0.039 13.7 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Barstar PF01337.18 EIM81493.1 - 0.15 12.1 0.5 3.8 7.6 0.0 3.6 4 0 0 4 4 4 0 Barstar (barnase inhibitor) AAA_7 PF12775.7 EIM81493.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region YjeF_N PF03853.15 EIM81494.1 - 2.2e-37 128.6 0.0 2.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Dioxygenase_C PF00775.21 EIM81495.1 - 1.3e-09 37.7 0.0 2.9e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Dioxygenase F-box PF00646.33 EIM81496.1 - 0.0033 17.3 0.4 0.0066 16.3 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM81496.1 - 0.0061 16.4 1.6 0.0081 16.0 0.4 1.8 2 0 0 2 2 2 1 F-box-like Anti-TRAP PF15777.5 EIM81496.1 - 0.13 12.3 2.9 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_2 PF13639.6 EIM81497.1 - 3.8e-09 36.7 10.2 1.2e-06 28.7 3.8 3.4 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 EIM81497.1 - 1.1e-07 31.6 1.7 6.4e-05 22.7 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM81497.1 - 2.3e-07 31.0 9.3 9.7e-07 29.0 0.8 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EIM81497.1 - 9.5e-06 25.5 5.0 0.00036 20.5 2.9 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EIM81497.1 - 2e-05 24.2 8.7 0.00069 19.3 0.4 3.2 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_5 PF14634.6 EIM81497.1 - 8.4e-05 22.5 5.5 0.001 18.9 0.6 2.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM81497.1 - 0.00023 20.9 11.9 0.00045 20.0 3.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EIM81497.1 - 0.00097 18.7 0.4 0.00097 18.7 0.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EIM81497.1 - 0.0014 18.6 3.9 0.0034 17.4 0.2 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EIM81497.1 - 0.021 14.7 0.7 0.021 14.7 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM81497.1 - 0.06 13.2 3.8 0.059 13.2 1.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EIM81497.1 - 0.17 12.1 0.9 0.4 10.9 0.9 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EIM81497.1 - 0.27 11.4 3.8 2 8.7 0.3 2.8 3 0 0 3 3 2 0 FANCL C-terminal domain PHD PF00628.29 EIM81497.1 - 6.8 6.7 5.4 10 6.1 1.2 2.7 2 0 0 2 2 2 0 PHD-finger PhyH PF05721.13 EIM81498.1 - 8.1e-13 49.1 0.0 1.2e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Tyrosinase PF00264.20 EIM81499.1 - 1.6e-39 136.5 0.7 2.2e-39 136.1 0.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.22 EIM81500.1 - 4.4e-73 246.6 0.0 5.5e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF760 PF05542.11 EIM81500.1 - 0.095 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF760) Tyrosinase PF00264.20 EIM81501.1 - 1.8e-41 142.9 2.0 2.4e-41 142.5 2.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-MYND PF01753.18 EIM81504.1 - 4.6e-10 39.4 7.0 4.6e-10 39.4 7.0 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EIM81504.1 - 7.6e-05 22.7 0.6 0.00029 20.9 0.6 2.0 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 adh_short PF00106.25 EIM81505.1 - 9.6e-20 70.9 0.1 7.6e-18 64.7 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81505.1 - 2.1e-09 37.3 0.1 4.6e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81505.1 - 3.7e-08 33.5 0.1 5.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Lamprin PF06403.11 EIM81505.1 - 0.052 13.5 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 Lamprin Polysacc_synt_2 PF02719.15 EIM81505.1 - 0.06 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EIM81505.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1843 PF08898.10 EIM81505.1 - 0.21 12.1 0.2 3.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Malate_DH PF12434.8 EIM81506.1 - 0.0064 16.5 1.3 0.0064 16.5 1.3 1.9 2 0 0 2 2 2 1 Malate dehydrogenase enzyme Mucin PF01456.17 EIM81507.1 - 0.27 11.2 4.6 0.49 10.4 4.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Nop PF01798.18 EIM81508.1 - 5.3e-86 287.8 0.2 2e-85 285.9 0.0 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EIM81508.1 - 2.2e-22 79.2 0.2 2.2e-22 79.2 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Pro-kuma_activ PF09286.11 EIM81511.1 - 7e-31 107.4 0.0 1.3e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM81511.1 - 0.002 17.4 0.1 0.0028 17.0 0.1 1.4 1 1 0 1 1 1 1 Subtilase family RhoGAP PF00620.27 EIM81513.1 - 4.1e-31 107.9 0.0 6.3e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 EIM81513.1 - 1.8e-30 105.9 0.2 3.9e-30 104.8 0.2 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EIM81513.1 - 2.8e-05 23.9 0.3 0.00038 20.2 0.3 2.2 1 1 0 1 1 1 1 CRAL/TRIO domain DEC-1_C PF04626.13 EIM81513.1 - 0.08 13.3 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Na_H_Exchanger PF00999.21 EIM81514.1 - 1.4e-51 175.5 43.7 1.9e-51 175.1 43.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ThuA PF06283.11 EIM81515.1 - 3.4e-62 210.4 0.6 4e-62 210.1 0.6 1.1 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.6 EIM81515.1 - 0.036 13.5 0.0 0.048 13.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4159) DDOST_48kD PF03345.14 EIM81515.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta TssN PF17555.2 EIM81516.1 - 0.063 12.6 0.5 0.1 12.0 0.5 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN Phage_holin_3_6 PF07332.11 EIM81516.1 - 0.083 12.9 1.0 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1270 PF06900.11 EIM81516.1 - 0.21 12.0 0.4 0.21 12.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Peroxidase_ext PF11895.8 EIM81517.1 - 5.7e-28 96.7 0.7 1.5e-27 95.4 0.7 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 EIM81517.1 - 3.3e-26 92.4 0.0 6.6e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Peroxidase bZIP_1 PF00170.21 EIM81518.1 - 1.7e-06 28.0 5.9 2.7e-06 27.4 5.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EIM81518.1 - 1.6e-05 24.9 10.1 1.6e-05 24.9 10.1 1.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EIM81518.1 - 0.013 16.0 5.3 0.013 16.0 5.3 1.6 1 1 1 2 2 2 0 bZIP Maf transcription factor Gtr1_RagA PF04670.12 EIM81519.1 - 2.2e-40 138.5 0.0 3.5e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_hydro_28 PF00295.17 EIM81520.1 - 6e-51 173.4 17.4 7.7e-51 173.1 17.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.8 EIM81520.1 - 0.058 13.1 0.2 1.1 9.0 0.0 2.9 4 0 0 4 4 4 0 N terminal extension of bacteriophage endosialidase Pectinesterase PF01095.19 EIM81521.1 - 0.019 13.7 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Pectinesterase Pectinesterase PF01095.19 EIM81522.1 - 3.4e-35 121.2 0.3 4e-35 121.0 0.3 1.0 1 0 0 1 1 1 1 Pectinesterase GDA1_CD39 PF01150.17 EIM81523.1 - 7e-91 305.0 0.0 9.2e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GMC_oxred_C PF05199.13 EIM81524.1 - 1.2e-13 51.8 0.0 3e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EIM81524.1 - 6.1e-07 29.1 0.0 2.3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 EIM81524.1 - 0.00012 21.8 0.3 0.00048 19.8 0.2 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM81524.1 - 0.03 14.6 0.2 0.096 12.9 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDI PF00996.18 EIM81524.1 - 0.22 10.0 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Methyltransf_16 PF10294.9 EIM81525.1 - 9.6e-16 58.0 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EIM81525.1 - 0.003 17.4 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIM81525.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UNC80 PF15778.5 EIM81525.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Cation channel complex component UNC80 GidB PF02527.15 EIM81525.1 - 0.061 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 EIM81525.1 - 0.083 13.6 0.1 0.42 11.3 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain ArAE_2_N PF10337.9 EIM81529.1 - 1.9e-72 244.8 0.0 1.9e-72 244.8 0.0 1.7 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EIM81529.1 - 5.5e-32 111.4 0.0 6.6e-30 104.6 0.0 2.6 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EIM81529.1 - 1.2e-09 38.4 13.2 1.2e-09 38.4 13.2 4.1 3 1 0 3 3 3 1 Fusaric acid resistance protein-like WLM PF08325.10 EIM81531.1 - 6.5e-56 189.4 0.0 1e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EIM81531.1 - 1.8e-06 27.1 1.6 1.8e-06 27.1 1.6 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Transketolase_C PF02780.20 EIM81531.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain DUF45 PF01863.17 EIM81531.1 - 0.032 14.3 0.2 0.059 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 C1_2 PF03107.16 EIM81531.1 - 0.056 13.8 6.2 0.29 11.5 2.6 2.6 1 1 1 2 2 2 0 C1 domain SVIP PF15811.5 EIM81531.1 - 0.074 13.5 3.5 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DZR PF12773.7 EIM81531.1 - 0.45 10.6 10.4 0.2 11.7 8.2 1.6 2 0 0 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 EIM81531.1 - 5 7.3 10.9 11 6.2 0.6 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger SPRY PF00622.28 EIM81532.1 - 8.8e-12 45.2 0.0 1.4e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Pkinase PF00069.25 EIM81533.1 - 5.3e-10 39.1 0.0 7.3e-09 35.4 0.0 2.3 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81533.1 - 0.0033 16.8 0.0 0.0077 15.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase GST_N_3 PF13417.6 EIM81534.1 - 6e-12 45.8 0.1 1.7e-11 44.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81534.1 - 2.3e-09 37.4 0.0 5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM81534.1 - 4.4e-05 23.6 0.0 0.00025 21.2 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM81534.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM81534.1 - 0.14 12.9 0.0 3.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 EIM81535.1 - 1.7e-12 47.6 0.1 4.7e-12 46.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81535.1 - 1.2e-08 35.1 0.1 3.1e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM81535.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM81535.1 - 0.072 13.4 0.0 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM81535.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.23 EIM81536.1 - 1.1e-21 77.1 0.6 4.6e-21 75.0 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EIM81536.1 - 0.00077 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like NMO PF03060.15 EIM81537.1 - 1.4e-54 185.7 0.2 7.3e-54 183.4 0.2 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EIM81537.1 - 9.8e-11 41.2 0.0 3.1e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EIM81537.1 - 0.0019 17.3 0.7 0.003 16.6 0.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.17 EIM81537.1 - 0.016 14.5 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 EIM81537.1 - 0.02 14.0 0.1 0.036 13.2 0.1 1.6 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 EIM81537.1 - 0.054 12.7 0.1 0.088 12.0 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NanE PF04131.14 EIM81537.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.12 EIM81537.1 - 0.19 10.9 0.1 0.47 9.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF561) Abhydrolase_6 PF12697.7 EIM81539.1 - 2.6e-13 51.1 4.1 4.1e-13 50.4 4.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM81539.1 - 0.0061 16.2 0.5 0.019 14.6 0.3 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM81539.1 - 0.096 11.9 0.0 0.38 10.0 0.0 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EIM81539.1 - 0.18 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GST_N_3 PF13417.6 EIM81540.1 - 1.6e-12 47.6 0.0 3.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81540.1 - 5.2e-09 36.3 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM81540.1 - 0.018 15.3 0.0 0.77 10.1 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM81540.1 - 0.018 15.2 0.0 0.056 13.6 0.0 1.8 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LRR_8 PF13855.6 EIM81541.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.0 3 0 0 3 3 3 0 Leucine rich repeat Myf5 PF12232.8 EIM81542.1 - 1.1 10.1 15.9 0.092 13.5 8.7 2.5 3 0 0 3 3 3 0 Myogenic determination factor 5 Pkinase PF00069.25 EIM81543.1 - 2.1e-54 184.7 0.1 2.4e-54 184.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81543.1 - 6.7e-28 97.7 0.1 8.4e-28 97.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM81543.1 - 2.3e-05 23.9 0.2 0.00062 19.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EIM81543.1 - 0.00036 20.2 1.0 0.0025 17.4 0.3 2.0 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 EIM81543.1 - 0.003 17.2 0.2 0.38 10.3 0.1 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIM81543.1 - 0.0067 15.8 0.1 0.0098 15.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM81543.1 - 0.011 15.6 0.0 0.84 9.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM81543.1 - 0.023 13.5 0.1 0.046 12.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase HAD_2 PF13419.6 EIM81544.1 - 0.0053 16.9 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans PF00432.21 EIM81544.1 - 1.9 8.3 4.6 0.4 10.4 0.6 2.0 2 1 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat adh_short PF00106.25 EIM81545.1 - 2.5e-23 82.5 0.0 3.7e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81545.1 - 2.2e-13 50.3 0.0 1.5e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81545.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 0 KR domain FANC_SAP PF18081.1 EIM81545.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain Abhydrolase_6 PF12697.7 EIM81546.1 - 6.9e-14 53.0 1.8 1.1e-13 52.4 1.8 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM81546.1 - 0.00029 20.6 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 EIM81546.1 - 0.063 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 EIM81547.1 - 4e-12 47.2 0.7 5.7e-12 46.7 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM81547.1 - 0.00017 21.4 0.0 0.00049 19.8 0.0 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF726 PF05277.12 EIM81547.1 - 0.0016 17.5 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3435 PF11917.8 EIM81547.1 - 0.037 13.0 0.0 0.05 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Glyco_transf_28 PF03033.20 EIM81548.1 - 7e-28 97.4 0.0 1.4e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EIM81548.1 - 1.4e-07 31.4 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.18 EIM81548.1 - 8.8e-06 24.8 0.0 2.1e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 EIM81548.1 - 0.0002 21.8 0.1 0.00086 19.8 0.0 2.1 2 0 0 2 2 2 1 PH domain Glyco_transf_4 PF13439.6 EIM81548.1 - 0.043 13.8 0.1 0.62 10.0 0.0 2.7 2 1 0 3 3 3 0 Glycosyltransferase Family 4 PH_10 PF15411.6 EIM81548.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain F-box-like PF12937.7 EIM81549.1 - 9.9e-13 47.8 0.2 2.7e-12 46.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM81550.1 - 6.7e-08 32.3 0.1 4.2e-06 26.5 0.0 3.1 2 0 0 2 2 2 2 F-box-like LRR_4 PF12799.7 EIM81552.1 - 0.022 15.2 1.6 2.3 8.8 0.0 3.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) DUF1979 PF09322.10 EIM81552.1 - 0.3 11.0 0.9 1.1 9.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) Neprosin_AP PF14365.6 EIM81553.1 - 0.096 13.2 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Neprosin activation peptide PIF1 PF05970.14 EIM81554.1 - 9e-08 31.7 0.0 3.1e-05 23.3 0.0 2.5 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EIM81557.1 - 5.7e-20 72.3 0.0 6.7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DarA_N PF18788.1 EIM81559.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Defence against restriction A N-terminal DUF1840 PF08895.11 EIM81560.1 - 7.8 6.9 7.9 41 4.6 7.9 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) WD40 PF00400.32 EIM81563.1 - 1.4e-88 288.5 48.4 3.6e-10 40.3 0.3 15.3 15 0 0 15 15 14 13 WD domain, G-beta repeat DUF2235 PF09994.9 EIM81563.1 - 3.5e-53 180.8 0.2 7.3e-53 179.8 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ANAPC4_WD40 PF12894.7 EIM81563.1 - 2.1e-32 111.3 0.5 8.2e-05 22.8 0.0 10.7 1 1 10 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM81563.1 - 6.8e-11 41.5 7.2 0.26 9.9 0.2 8.3 3 3 4 8 8 8 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EIM81563.1 - 9.2e-10 38.0 0.3 0.038 13.0 0.0 7.3 3 3 6 9 9 9 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EIM81563.1 - 3.1e-08 33.5 0.8 0.001 18.7 0.0 3.7 2 2 1 3 3 3 2 PQQ-like domain WD40_like PF17005.5 EIM81563.1 - 5.5e-08 32.5 0.0 9.8 5.4 0.0 8.0 10 0 0 10 10 10 1 WD40-like domain Cytochrom_D1 PF02239.16 EIM81563.1 - 1.4e-07 30.4 0.1 0.25 9.8 0.0 3.7 3 1 1 4 4 4 4 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EIM81563.1 - 4.2e-05 22.5 6.5 7.2 5.2 0.2 6.4 3 2 1 5 5 5 1 Nup133 N terminal like PD40 PF07676.12 EIM81563.1 - 0.0038 17.1 5.9 6.7 6.8 0.0 6.4 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EIM81563.1 - 0.005 16.2 1.4 12 5.1 0.0 4.8 4 2 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 EIM81563.1 - 0.042 13.8 0.0 36 4.5 0.0 4.8 5 0 0 5 5 5 0 PQQ enzyme repeat Frtz PF11768.8 EIM81563.1 - 0.17 10.2 0.0 7.4 4.7 0.0 2.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RHD3 PF05879.12 EIM81563.1 - 0.19 9.9 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF5570 PF17731.1 EIM81563.1 - 3.2 7.9 8.0 8.1 6.6 0.1 4.3 5 0 0 5 5 4 0 Family of unknown function (DUF5570) DUF659 PF04937.15 EIM81565.1 - 1.8e-09 37.6 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 EIM81565.1 - 6.4e-06 25.9 3.1 3.1e-05 23.7 0.3 3.0 3 1 0 3 3 3 1 hAT family C-terminal dimerisation region TctB PF07331.11 EIM81566.1 - 1.7 8.9 6.4 4.8 7.5 6.4 1.9 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Abhydrolase_6 PF12697.7 EIM81567.1 - 1.4e-09 38.9 0.1 2.3e-09 38.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM81567.1 - 0.0033 17.1 0.1 0.011 15.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM81568.1 - 4.5e-06 27.4 0.1 5.5e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM81568.1 - 0.00011 22.0 0.0 0.00019 21.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM81568.1 - 0.076 12.3 0.1 0.76 9.0 0.1 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM81569.1 - 0.00034 21.3 0.3 0.0004 21.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 EIM81571.1 - 3e-68 230.6 0.0 1.2e-67 228.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 EIM81572.1 - 5.6e-12 45.9 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81572.1 - 4.3e-09 36.5 0.1 8.8e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM81572.1 - 0.00028 21.0 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EIM81572.1 - 0.00031 21.0 0.0 0.00052 20.3 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 EIM81572.1 - 0.037 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM81572.1 - 0.13 13.0 0.0 5.1 7.9 0.0 2.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain TPP_enzyme_N PF02776.18 EIM81573.1 - 8.7e-34 116.6 0.1 1.2e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EIM81573.1 - 5.7e-14 52.0 0.0 1.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EIM81573.1 - 7.5e-13 48.5 0.0 5e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PALP PF00291.25 EIM81573.1 - 0.15 11.5 0.4 1.1 8.6 0.2 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme E1_DerP2_DerF2 PF02221.15 EIM81574.1 - 5.2e-24 85.2 0.1 6.1e-24 85.0 0.1 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EIM81574.1 - 0.00057 20.3 0.0 0.0017 18.7 0.0 1.8 1 1 0 1 1 1 1 ML-like domain DUF3077 PF11275.8 EIM81576.1 - 0.062 13.5 0.1 8.5 6.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3077) F-box-like PF12937.7 EIM81577.1 - 1.8e-07 30.9 0.9 4.6e-07 29.6 0.9 1.7 1 0 0 1 1 1 1 F-box-like GbpC PF08363.10 EIM81577.1 - 0.22 10.9 0.1 0.31 10.4 0.1 1.1 1 0 0 1 1 1 0 Glucan-binding protein C F-box-like PF12937.7 EIM81578.1 - 3.4e-05 23.7 0.2 3.4e-05 23.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM81578.1 - 0.0029 18.0 1.7 0.2 12.1 0.2 3.8 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM81578.1 - 0.074 12.8 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat His_Phos_1 PF00300.22 EIM81579.1 - 1.1e-12 48.0 1.3 2.2e-08 34.1 0.2 3.4 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Ribosomal_S19e PF01090.19 EIM81580.1 - 1.2e-56 190.2 0.1 1.4e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.7 EIM81582.1 - 4.4e-10 39.3 0.9 1e-09 38.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81582.1 - 0.052 13.5 2.4 0.8 9.7 0.2 2.6 2 0 0 2 2 2 0 F-box domain DUF3077 PF11275.8 EIM81583.1 - 0.032 14.4 0.1 7.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) Vac_ImportDeg PF09783.9 EIM81585.1 - 0.035 13.9 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Vacuolar import and degradation protein Glyco_trans_2_3 PF13632.6 EIM81586.1 - 3.8e-57 193.4 1.2 3.8e-57 193.4 1.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIM81586.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIM81586.1 - 0.0014 18.4 0.0 0.077 12.8 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIM81586.1 - 0.05 13.1 0.0 0.17 11.4 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 21 LRR_8 PF13855.6 EIM81587.1 - 0.099 12.4 1.0 0.48 10.2 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat CFEM PF05730.11 EIM81589.1 - 9.8e-10 38.4 10.6 1.8e-09 37.5 10.6 1.5 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 EIM81589.1 - 0.023 14.1 0.1 0.023 14.1 0.1 3.4 4 0 0 4 4 4 0 Transmembrane alpha-helix domain GRP PF07172.11 EIM81589.1 - 0.028 15.1 11.5 0.11 13.1 11.5 2.1 1 0 0 1 1 1 0 Glycine rich protein family 7TM-7TMR_HD PF07698.11 EIM81589.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase His_Phos_1 PF00300.22 EIM81590.1 - 8.4e-26 90.9 0.1 1.3e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-AN1 PF01428.16 EIM81591.1 - 1.6e-21 76.1 30.6 4e-11 42.9 9.4 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EIM81591.1 - 0.013 15.8 19.3 0.3 11.5 3.2 2.5 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain Rep_fac-A_C PF08646.10 EIM81591.1 - 4.5 7.0 9.2 0.065 13.0 1.8 1.7 2 0 0 2 2 2 0 Replication factor-A C terminal domain RSN1_7TM PF02714.15 EIM81592.1 - 3.1e-41 141.5 23.0 5e-41 140.8 23.0 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EIM81592.1 - 1.9e-20 73.8 0.0 8e-14 52.3 0.0 3.3 3 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EIM81592.1 - 6.9e-19 68.1 2.2 1.1e-18 67.5 0.1 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 EIM81592.1 - 0.085 13.0 0.5 0.25 11.5 0.5 1.8 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter ETC_C1_NDUFA4 PF04800.12 EIM81593.1 - 6.8e-37 125.6 0.1 8e-37 125.4 0.1 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region F-box-like PF12937.7 EIM81594.1 - 3.1e-06 27.0 0.4 7.8e-06 25.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like Glyoxalase_4 PF13669.6 EIM81595.1 - 5.1e-05 23.5 0.0 5.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EIM81595.1 - 0.00034 21.4 0.0 0.00036 21.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EIM81595.1 - 0.00084 19.5 0.0 0.00092 19.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EIM81595.1 - 0.0027 17.6 0.0 0.0057 16.6 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain DUF5456 PF17539.2 EIM81595.1 - 0.0081 16.0 0.0 0.0094 15.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5456) Glyoxalase_3 PF13468.6 EIM81595.1 - 0.03 14.4 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Plk4_PB1 PF18190.1 EIM81596.1 - 2e-08 34.3 0.0 4.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 EIM81596.1 - 0.0027 18.4 0.0 0.046 14.4 0.0 2.6 3 0 0 3 3 3 1 Polo-like Kinase 4 Polo Box 2 Exo_endo_phos PF03372.23 EIM81597.1 - 8.6e-09 35.2 1.6 4.1e-08 33.0 0.7 2.2 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EIM81597.1 - 0.13 12.1 0.4 2.5 8.0 0.1 2.8 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Abhydrolase_6 PF12697.7 EIM81598.1 - 1.9e-10 41.7 10.3 3.3e-10 41.0 10.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM81598.1 - 2.6e-07 30.5 0.1 5.7e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 EIM81598.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.4 2 0 0 2 2 2 0 Serine carboxypeptidase Lipase_GDSL PF00657.22 EIM81599.1 - 1.7e-06 28.1 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIM81599.1 - 6.9e-06 26.6 0.4 1.1e-05 25.9 0.1 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Omega-toxin PF06357.11 EIM81599.1 - 0.056 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Omega-atracotoxin Lipase_GDSL PF00657.22 EIM81600.1 - 4.7e-08 33.2 0.0 9.3e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIM81600.1 - 0.0012 19.3 4.9 0.0085 16.5 3.9 2.5 2 1 1 3 3 3 1 GDSL-like Lipase/Acylhydrolase family 3Beta_HSD PF01073.19 EIM81601.1 - 1.9e-69 233.8 0.1 5.8e-63 212.5 0.1 2.4 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM81601.1 - 1.4e-36 126.2 0.0 2e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81601.1 - 2.6e-18 66.5 0.1 2.3e-14 53.5 0.1 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM81601.1 - 3e-14 53.3 0.0 4.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EIM81601.1 - 1.6e-12 47.2 0.0 2.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EIM81601.1 - 3.3e-11 42.8 0.1 2e-07 30.5 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EIM81601.1 - 5.2e-08 32.4 2.2 1.8e-06 27.4 2.2 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EIM81601.1 - 7.4e-05 22.4 1.0 0.00049 19.7 1.0 2.0 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 EIM81601.1 - 0.0038 17.1 0.4 0.019 14.9 0.4 2.1 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EIM81601.1 - 0.13 12.6 1.1 0.52 10.6 1.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Nbl1_Borealin_N PF10444.9 EIM81602.1 - 3.1e-13 49.1 0.1 5.1e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 EIM81602.1 - 0.014 15.4 15.7 0.98 9.4 6.0 3.6 3 1 0 3 3 3 0 Cell division cycle-associated protein 8 3Beta_HSD PF01073.19 EIM81603.1 - 7.7e-63 212.1 0.0 7.9e-58 195.7 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM81603.1 - 4e-34 118.2 0.0 5.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81603.1 - 7.1e-20 71.7 0.0 3.1e-15 56.4 0.1 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM81603.1 - 2.9e-12 46.9 0.0 7.9e-12 45.4 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EIM81603.1 - 3.1e-10 39.6 0.0 4.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EIM81603.1 - 6.9e-10 38.5 0.0 1.2e-05 24.6 0.0 2.4 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EIM81603.1 - 2.5e-05 23.6 0.7 0.00023 20.4 0.7 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EIM81603.1 - 0.00031 20.4 0.4 0.0013 18.3 0.4 1.9 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 EIM81603.1 - 0.0033 17.3 0.9 0.12 12.2 0.1 2.3 1 1 1 2 2 2 1 KR domain TrkA_N PF02254.18 EIM81603.1 - 0.15 12.4 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 EIM81604.1 - 7.5e-67 225.3 0.0 1.3e-62 211.4 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM81604.1 - 9e-36 123.5 0.0 1.2e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81604.1 - 3.8e-21 75.8 0.0 7.7e-17 61.7 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM81604.1 - 2.4e-13 49.9 0.0 4e-08 32.7 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EIM81604.1 - 1.1e-12 48.2 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EIM81604.1 - 5.6e-12 45.4 0.0 7.6e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIM81604.1 - 8.6e-06 25.1 0.2 0.00045 19.5 1.2 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EIM81604.1 - 2.2e-05 24.1 1.5 4.6e-05 23.1 0.5 2.0 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 EIM81604.1 - 0.00039 20.4 1.7 0.01 15.7 0.6 2.6 1 1 1 2 2 2 2 KR domain TrkA_N PF02254.18 EIM81604.1 - 0.024 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 EIM81604.1 - 0.087 12.3 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 EIM81605.1 - 2.5e-18 66.1 0.0 3.4e-17 62.4 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM81605.1 - 6.7e-11 41.8 0.0 6.5e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 EIM81605.1 - 3.6e-10 39.7 0.0 1.3e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81605.1 - 3.3e-05 23.5 0.0 0.007 15.8 0.0 3.1 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase VWA_3 PF13768.6 EIM81605.1 - 0.00078 19.4 0.0 0.081 12.9 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain NAD_binding_10 PF13460.6 EIM81605.1 - 0.047 13.6 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding POP1 PF06978.11 EIM81606.1 - 4.7e-43 147.6 20.1 7.3e-24 84.9 2.4 3.2 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EIM81606.1 - 1.5e-27 95.8 2.6 1.5e-27 95.8 2.6 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T_C PF08669.11 EIM81606.1 - 0.00031 20.6 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.21 EIM81606.1 - 0.0064 15.9 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain CALCOCO1 PF07888.11 EIM81607.1 - 0.0013 17.7 0.6 0.0013 17.7 0.6 1.5 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Seryl_tRNA_N PF02403.22 EIM81607.1 - 0.0032 17.7 1.2 0.0049 17.1 1.2 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain RP-C PF03428.13 EIM81607.1 - 0.0045 16.7 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain DHR10 PF18595.1 EIM81607.1 - 0.0069 16.4 3.4 0.011 15.7 3.4 1.3 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain RRF PF01765.19 EIM81607.1 - 0.0087 16.0 0.6 0.014 15.4 0.6 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Spc7 PF08317.11 EIM81607.1 - 0.0092 14.9 1.3 0.012 14.5 1.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CHASE3 PF05227.13 EIM81607.1 - 0.012 15.5 1.1 0.023 14.6 0.6 1.6 1 1 0 1 1 1 0 CHASE3 domain BLOC1_2 PF10046.9 EIM81607.1 - 0.019 15.3 1.4 0.036 14.4 1.3 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EIM81607.1 - 0.019 15.4 1.1 0.071 13.6 1.0 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 EIM81607.1 - 0.035 14.4 2.1 0.13 12.5 1.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein DASH_Dam1 PF08653.10 EIM81607.1 - 0.046 13.5 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 FapA PF03961.13 EIM81607.1 - 0.057 12.0 0.3 0.07 11.7 0.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 EIM81607.1 - 0.1 12.6 1.6 0.32 11.1 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EIM81607.1 - 0.11 13.0 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 CCDC-167 PF15188.6 EIM81607.1 - 0.41 11.0 3.3 0.24 11.8 1.3 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.11 EIM81607.1 - 0.65 10.4 2.8 7.7 7.0 0.3 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CCDC53 PF10152.9 EIM81610.1 - 0.058 13.8 0.0 0.058 13.8 0.0 3.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex 4HBT_3 PF13622.6 EIM81610.1 - 0.091 13.0 0.7 0.23 11.7 0.7 1.7 1 0 0 1 1 1 0 Thioesterase-like superfamily Zn_clus PF00172.18 EIM81611.1 - 9.4e-07 28.9 9.7 1.7e-06 28.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tom22 PF04281.13 EIM81612.1 - 1.1e-39 135.4 0.2 1.3e-39 135.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Nab2 PF11517.8 EIM81612.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) RicinB_lectin_2 PF14200.6 EIM81613.1 - 3.6e-22 78.9 1.6 6.1e-11 42.9 0.2 4.3 2 1 1 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EIM81613.1 - 2.2e-06 27.9 2.0 9.5e-06 25.9 2.0 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CMAS PF02353.20 EIM81614.1 - 8.7e-62 208.9 1.0 2.5e-49 168.1 0.1 2.8 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EIM81614.1 - 3.3e-10 40.5 0.0 7.5e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM81614.1 - 1.9e-07 31.6 0.0 4.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM81614.1 - 9.1e-06 26.3 0.0 2.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM81614.1 - 0.0027 17.5 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM81614.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 EIM81614.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GCD14 PF08704.10 EIM81614.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Met_10 PF02475.16 EIM81614.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 EIM81614.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase RicinB_lectin_2 PF14200.6 EIM81615.1 - 8.4e-11 42.5 0.0 0.0042 17.8 0.0 4.2 3 1 2 5 5 5 3 Ricin-type beta-trefoil lectin domain-like Rif1_N PF12231.8 EIM81616.1 - 2.2e-05 23.6 0.0 0.00017 20.7 0.0 2.3 3 0 0 3 3 3 1 Rap1-interacting factor 1 N terminal CD99L2 PF12301.8 EIM81616.1 - 0.16 12.3 5.3 0.42 10.9 5.3 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 GPI-anchored PF10342.9 EIM81617.1 - 2e-09 38.1 0.1 3.3e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Lipase_3 PF01764.25 EIM81619.1 - 9.3e-26 90.4 0.0 1.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EIM81619.1 - 0.00026 20.8 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EIM81619.1 - 0.00048 20.8 0.3 0.00079 20.1 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EIM81619.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 EIM81619.1 - 0.036 13.6 0.1 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 EIM81619.1 - 0.066 12.7 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EIM81619.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GPI-anchored PF10342.9 EIM81620.1 - 6.2e-09 36.5 0.3 8.3e-09 36.1 0.3 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SIR2 PF02146.17 EIM81621.1 - 6.1e-53 179.4 0.0 8.8e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Cullin PF00888.22 EIM81622.1 - 6e-19 68.1 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EIM81622.1 - 3.2e-15 56.4 0.0 2.6e-14 53.5 0.0 2.5 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 MFS_1 PF07690.16 EIM81623.1 - 3.4e-18 65.7 48.5 6.3e-18 64.8 45.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EIM81624.1 - 6.7e-17 61.4 42.4 6.7e-17 61.4 42.4 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily UCH PF00443.29 EIM81625.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 EIM81625.1 - 0.23 11.8 1.6 22 5.7 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat GPI-anchored PF10342.9 EIM81626.1 - 1.8e-09 38.2 1.4 2.1e-09 38.0 1.4 1.0 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family A_deaminase PF00962.22 EIM81628.1 - 2.2e-121 405.2 0.6 3e-121 404.8 0.6 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Potex_coat PF06184.11 EIM81629.1 - 0.0033 17.0 0.6 0.0066 16.0 0.2 1.7 1 1 0 2 2 2 1 Potexvirus coat protein PE PF00934.20 EIM81629.1 - 0.034 14.5 1.1 0.071 13.4 1.1 1.5 1 0 0 1 1 1 0 PE family Ribosomal_L22 PF00237.19 EIM81630.1 - 6.3e-35 119.5 0.1 8.8e-35 119.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RICTOR_N PF14664.6 EIM81631.1 - 1.1e-121 406.3 0.8 4.5e-121 404.4 0.3 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EIM81631.1 - 6.3e-41 138.4 0.0 2.4e-37 126.8 0.0 4.6 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EIM81631.1 - 1.9e-35 121.5 0.0 9.4e-34 116.1 0.0 3.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EIM81631.1 - 8.9e-31 105.9 0.0 3.1e-28 97.8 0.0 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EIM81631.1 - 0.019 15.1 2.3 0.041 14.0 2.3 1.6 1 0 0 1 1 1 0 Hr1 repeat HEAT PF02985.22 EIM81631.1 - 0.038 14.2 0.2 22 5.7 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat Proteasom_PSMB PF10508.9 EIM81631.1 - 0.16 10.5 2.3 3.4 6.1 0.0 3.7 4 0 0 4 4 4 0 Proteasome non-ATPase 26S subunit Epimerase PF01370.21 EIM81632.1 - 2e-23 83.1 0.1 6e-23 81.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM81632.1 - 6.3e-19 68.0 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM81632.1 - 1.7e-14 54.0 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM81632.1 - 2.2e-14 53.8 0.1 2.9e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM81632.1 - 7.1e-12 45.0 0.0 8.9e-10 38.2 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EIM81632.1 - 3.1e-08 33.5 0.7 4.4e-08 33.0 0.7 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EIM81632.1 - 9.5e-05 21.7 0.2 0.00057 19.1 0.3 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EIM81632.1 - 0.00011 21.5 0.1 0.16 11.0 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 EIM81632.1 - 0.0084 15.6 3.1 0.23 10.9 3.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM81632.1 - 0.033 14.1 1.5 0.25 11.2 1.5 2.0 1 1 0 1 1 1 0 KR domain MciZ PF13072.6 EIM81632.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ GST_N_3 PF13417.6 EIM81633.1 - 1.2e-14 54.5 0.0 2.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81633.1 - 4.3e-09 36.5 0.0 9.9e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM81633.1 - 0.00014 22.0 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM81633.1 - 0.00027 20.9 0.1 0.00076 19.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM81633.1 - 0.0057 16.8 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM81633.1 - 0.04 14.7 0.0 0.28 11.9 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain F-box-like PF12937.7 EIM81634.1 - 4.3e-11 42.5 0.6 4.3e-11 42.5 0.6 2.3 2 0 0 2 2 2 1 F-box-like GST_N_3 PF13417.6 EIM81635.1 - 4.6e-08 33.3 0.0 7.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81635.1 - 5.6e-07 29.8 0.1 9.5e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain D123 PF07065.14 EIM81636.1 - 7.8e-98 327.4 0.0 9e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 EIM81636.1 - 0.018 15.1 0.1 0.04 13.9 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 DNA_pol_phi PF04931.13 EIM81636.1 - 0.4 8.7 2.0 0.57 8.2 2.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EIM81636.1 - 4.7 7.7 9.2 0.11 12.9 2.8 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FA_desaturase PF00487.24 EIM81637.1 - 2.3e-19 70.3 26.3 6.1e-19 68.9 26.3 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EIM81637.1 - 0.0041 17.3 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Epimerase PF01370.21 EIM81638.1 - 3.4e-19 69.3 0.2 2.6e-18 66.4 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81638.1 - 4.4e-10 39.5 0.4 1.5e-09 37.8 0.3 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM81638.1 - 2.2e-09 36.7 0.0 3.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM81638.1 - 5.1e-07 29.8 1.1 1.1e-06 28.7 1.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM81638.1 - 1.4e-05 24.4 0.1 0.00065 18.9 0.1 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EIM81638.1 - 0.00035 20.2 0.9 0.00073 19.2 0.7 1.7 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EIM81638.1 - 0.0044 16.2 0.7 0.056 12.5 0.2 2.6 2 1 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EIM81638.1 - 0.0052 16.7 2.2 0.034 14.1 2.2 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM81638.1 - 0.0086 15.2 0.2 0.022 13.9 0.2 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EIM81638.1 - 0.023 14.1 0.9 0.023 14.1 0.9 2.1 2 1 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.21 EIM81639.1 - 5.6e-19 68.6 0.0 1.6e-11 44.1 0.0 2.0 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81639.1 - 6.7e-10 38.9 0.1 1.2e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM81639.1 - 1.1e-07 31.2 0.0 3e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM81639.1 - 1.5e-06 28.3 0.4 2.3e-06 27.6 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM81639.1 - 1.7e-05 24.1 0.0 7.5e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EIM81639.1 - 0.0032 16.9 2.2 0.004 16.6 0.8 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EIM81639.1 - 0.057 13.0 0.5 0.094 12.3 0.5 1.3 1 0 0 1 1 1 0 NmrA-like family Pkinase PF00069.25 EIM81640.1 - 8.3e-13 48.3 0.0 1.4e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 EIM81640.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EIM81640.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EIM81640.1 - 0.018 14.3 0.0 0.063 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase APH PF01636.23 EIM81640.1 - 0.042 13.8 0.4 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_3 PF13302.7 EIM81642.1 - 9.3e-21 75.0 0.0 1.1e-20 74.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM81642.1 - 7.3e-11 42.3 0.0 9.2e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EIM81642.1 - 3.3e-10 40.3 0.0 3.9e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM81642.1 - 2.3e-05 24.3 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM81642.1 - 0.00025 21.4 0.1 0.00034 21.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EIM81642.1 - 0.0019 17.9 0.0 0.0044 16.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM81642.1 - 0.0027 17.6 0.1 0.0052 16.7 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein DUF2205 PF10224.9 EIM81643.1 - 2.1e-10 40.4 0.8 2.6e-10 40.1 0.8 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 EIM81643.1 - 0.038 14.6 0.9 0.046 14.3 0.9 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Usp PF00582.26 EIM81644.1 - 1.5e-19 71.0 0.0 1.5e-19 71.0 0.0 2.6 3 0 0 3 3 3 1 Universal stress protein family Peptidase_M3 PF01432.20 EIM81645.1 - 1.2e-133 446.7 0.0 1.8e-133 446.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EIM81645.1 - 0.054 13.1 0.2 0.093 12.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Pet127 PF08634.10 EIM81646.1 - 6.1e-103 344.0 0.0 1.2e-102 343.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Arf PF00025.21 EIM81647.1 - 2.2e-42 144.5 0.0 2.6e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EIM81647.1 - 8.2e-19 67.8 0.0 1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM81647.1 - 6.7e-15 55.4 0.0 9.7e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EIM81647.1 - 2.6e-09 36.8 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EIM81647.1 - 2.4e-08 33.6 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIM81647.1 - 1.6e-06 28.2 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EIM81647.1 - 4.3e-06 26.1 1.0 5.5e-05 22.5 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 EIM81647.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EIM81647.1 - 0.022 14.8 0.5 0.35 10.9 0.8 2.1 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 EIM81647.1 - 0.044 13.5 0.1 8.2 6.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF751 PF05421.11 EIM81647.1 - 0.051 14.3 0.3 0.086 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF751) DUF4508 PF14969.6 EIM81647.1 - 0.11 12.8 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) RPN13_C PF16550.5 EIM81648.1 - 1e-29 102.9 0.1 1.5e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 EIM81648.1 - 3e-28 98.2 0.0 4.2e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Pro_isomerase PF00160.21 EIM81649.1 - 7.9e-49 165.9 0.0 1.5e-48 165.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EIM81649.1 - 2.5e-08 34.5 4.2 0.0014 19.4 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM81649.1 - 0.043 14.1 0.0 6 7.3 0.0 3.2 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain 2OG-FeII_Oxy_2 PF13532.6 EIM81650.1 - 9.4e-33 114.1 0.0 5.1e-31 108.4 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 EIM81651.1 - 0.002 18.0 4.7 0.0031 17.4 2.5 2.4 2 1 0 2 2 2 1 F-box-like GST_N PF02798.20 EIM81652.1 - 1e-16 61.0 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM81652.1 - 1.2e-11 44.9 0.0 2.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81652.1 - 7.9e-09 35.7 0.1 1.4e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM81652.1 - 5.3e-05 23.3 0.0 8.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM81652.1 - 6.9e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM81652.1 - 0.0025 18.0 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nas2_N PF18265.1 EIM81653.1 - 3.5e-25 87.7 0.0 4.7e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 EIM81653.1 - 3.6e-07 30.6 0.0 5.2e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EIM81653.1 - 4.5e-06 26.4 2.3 2e-05 24.3 0.9 2.6 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EIM81653.1 - 0.0028 18.0 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Septin PF00735.18 EIM81654.1 - 2.9e-44 151.5 0.0 2.5e-16 59.8 0.0 3.6 4 0 0 4 4 4 3 Septin GTP_EFTU PF00009.27 EIM81654.1 - 0.00018 21.1 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIM81654.1 - 0.00024 21.2 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EIM81654.1 - 0.0057 16.9 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIM81654.1 - 0.022 15.2 0.1 0.082 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EIM81654.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 EIM81654.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase Pox_A32 PF04665.12 EIM81654.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Gti1_Pac2 PF09729.9 EIM81655.1 - 1.3e-42 145.9 1.4 2.6e-35 122.1 0.0 2.9 2 1 1 3 3 3 2 Gti1/Pac2 family Alg6_Alg8 PF03155.15 EIM81656.1 - 4.7e-136 454.6 17.2 6.4e-136 454.1 17.2 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SLATT_1 PF18181.1 EIM81656.1 - 3.9 7.4 4.5 1.2 9.1 0.2 2.3 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 4HBT PF03061.22 EIM81657.1 - 7.1e-12 45.5 0.1 1.2e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EIM81657.1 - 0.007 16.5 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 EIM81657.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.4 1 1 1 2 2 2 0 Thioesterase-like superfamily Tam41_Mmp37 PF09139.11 EIM81658.1 - 2.8e-112 375.3 0.0 3.3e-112 375.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial ILVD_EDD PF00920.21 EIM81659.1 - 1.6e-204 680.3 0.0 1.9e-204 680.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family EIF4E-T PF10477.9 EIM81660.1 - 0.00031 19.7 0.1 0.00031 19.7 0.1 4.4 4 1 0 4 4 4 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NOA36 PF06524.12 EIM81660.1 - 1.3 8.3 17.7 1.1 8.6 2.7 2.5 2 0 0 2 2 2 0 NOA36 protein Septin PF00735.18 EIM81661.1 - 1.3e-31 109.9 0.0 1.5e-10 40.8 0.1 3.2 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 EIM81661.1 - 3.7e-18 65.4 26.7 2.8e-09 37.0 10.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.10 EIM81661.1 - 1.5 8.1 19.3 3.6 6.8 10.9 2.4 2 0 0 2 2 2 0 BUD22 F-actin_cap_A PF01267.17 EIM81662.1 - 8.3e-99 330.3 0.0 9.4e-99 330.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ICL PF00463.21 EIM81663.1 - 7.4e-260 862.9 0.4 8.5e-260 862.7 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EIM81663.1 - 6.4e-10 38.9 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glycos_transf_4 PF00953.21 EIM81664.1 - 9.6e-31 106.9 5.5 9.6e-31 106.9 5.5 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 SET PF00856.28 EIM81665.1 - 1.4e-07 32.1 0.0 3.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 SET domain MRC1 PF09444.10 EIM81665.1 - 0.28 11.7 0.7 0.49 10.9 0.7 1.3 1 0 0 1 1 1 0 MRC1-like domain DUF4470 PF14737.6 EIM81666.1 - 1.9e-23 82.5 0.0 9.6e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EIM81666.1 - 7e-11 42.0 15.5 1.6e-10 40.8 15.5 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM81666.1 - 4.3 7.7 10.1 11 6.4 10.1 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Malic_M PF03949.15 EIM81667.1 - 3.1e-89 298.6 0.0 4.2e-89 298.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EIM81667.1 - 1.6e-63 213.8 0.0 2.4e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MRP-L20 PF12824.7 EIM81668.1 - 3.7e-30 105.3 6.9 8e-30 104.2 6.5 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EIM81668.1 - 0.0013 18.8 0.3 0.0018 18.3 0.3 1.2 1 0 0 1 1 1 1 Neugrin BSD PF03909.17 EIM81669.1 - 1.1e-06 28.5 0.4 3.1e-06 27.1 0.4 1.8 1 0 0 1 1 1 1 BSD domain PTRF_SDPR PF15237.6 EIM81669.1 - 0.037 13.6 2.4 0.15 11.7 0.1 2.7 3 0 0 3 3 3 0 PTRF/SDPR family FWWh PF14922.6 EIM81669.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF883 PF05957.13 EIM81669.1 - 0.17 12.5 5.4 4.4 8.0 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 EIM81669.1 - 0.25 11.2 11.7 0.11 12.4 0.3 3.1 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Homeodomain PF00046.29 EIM81670.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain PAP1 PF08601.10 EIM81670.1 - 2.4 7.8 14.5 2.9 7.5 14.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 7TM_GPCR_Srj PF10319.9 EIM81672.1 - 0.077 12.3 0.0 7.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srj Dot_icm_IcmQ PF09475.10 EIM81673.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Arrestin_N PF00339.29 EIM81674.1 - 4.2e-09 36.6 0.1 3.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain GST_N_2 PF13409.6 EIM81675.1 - 1.9e-21 76.1 0.0 8.7e-21 74.0 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM81675.1 - 1.7e-20 73.2 0.0 3.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM81675.1 - 1.7e-15 57.1 0.9 5.9e-15 55.4 0.2 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM81675.1 - 0.0066 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM81675.1 - 0.0081 16.2 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EIM81675.1 - 0.011 16.3 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EIM81675.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Arm PF00514.23 EIM81675.1 - 0.097 12.7 0.2 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HAT_KAT11 PF08214.11 EIM81676.1 - 1.8e-36 126.1 0.0 1.3e-35 123.4 0.0 2.1 1 1 0 1 1 1 1 Histone acetylation protein DUF3915 PF13054.6 EIM81677.1 - 0.66 10.0 2.4 0.68 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF4106 PF13388.6 EIM81678.1 - 9.5 5.3 13.0 15 4.7 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF4810 PF16068.5 EIM81679.1 - 0.043 14.4 0.0 0.087 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) InvH PF04741.12 EIM81679.1 - 0.13 12.1 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 InvH outer membrane lipoprotein Arrestin_N PF00339.29 EIM81680.1 - 9.2e-12 45.2 0.6 2.9e-10 40.4 0.6 2.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Alpha-amylase PF00128.24 EIM81681.1 - 6.6e-60 203.4 3.9 1.1e-59 202.7 3.9 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EIM81681.1 - 2e-12 47.2 0.0 5.1e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL10 PF02638.15 EIM81681.1 - 0.019 14.0 0.2 0.033 13.3 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 hDGE_amylase PF14701.6 EIM81681.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_7 PF00840.20 EIM81682.1 - 9.2e-205 680.4 22.4 1.1e-204 680.2 22.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FMO-like PF00743.19 EIM81683.1 - 4.1e-15 55.2 0.3 1.4e-14 53.5 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EIM81683.1 - 2.3e-11 43.8 0.0 5.9e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EIM81683.1 - 3.2e-11 43.0 0.0 1.6e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EIM81683.1 - 3.7e-11 42.8 0.0 1.6e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM81683.1 - 1.4e-08 34.3 0.0 5.3e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM81683.1 - 0.0021 17.7 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM81683.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EIM81683.1 - 0.094 11.8 0.0 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 EIM81683.1 - 0.18 11.0 0.2 0.8 8.9 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Fcf2 PF08698.11 EIM81684.1 - 1.8e-29 102.0 0.1 3.9e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing ICMT PF04140.14 EIM81686.1 - 1.9e-15 57.0 0.1 4e-14 52.8 0.0 2.1 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM81686.1 - 3.8e-14 53.0 0.2 3.3e-13 50.0 0.2 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EIM81686.1 - 0.00032 20.3 0.1 0.00037 20.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EIM81686.1 - 0.0095 14.7 0.0 0.019 13.8 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Cullin PF00888.22 EIM81687.1 - 5.1e-187 623.3 15.2 8e-187 622.6 15.2 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EIM81687.1 - 4.6e-27 93.8 2.1 1.5e-26 92.2 2.1 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1727 PF08353.10 EIM81687.1 - 0.052 13.5 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Ubie_methyltran PF01209.18 EIM81690.1 - 1.1e-77 260.5 0.0 1.3e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EIM81690.1 - 7.3e-16 58.7 0.0 1.3e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM81690.1 - 9.6e-14 51.8 0.0 1.8e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM81690.1 - 3.3e-12 46.6 0.0 4.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM81690.1 - 3.3e-12 46.4 0.0 4.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM81690.1 - 3.2e-10 40.6 0.0 6.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DNA_pol_A_exo1 PF01612.20 EIM81693.1 - 4.1e-48 163.4 0.1 8.1e-48 162.4 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EIM81693.1 - 4.7e-25 88.1 2.1 8.6e-24 84.0 1.3 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EIM81693.1 - 3.1e-11 43.1 0.1 6.1e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 HRDC domain Hamartin PF04388.12 EIM81693.1 - 2.1 6.9 13.6 3.8 6.0 13.6 1.3 1 0 0 1 1 1 0 Hamartin protein Nucleoporin_FG PF13634.6 EIM81693.1 - 2.5 9.0 11.6 0.077 13.9 5.0 1.9 2 0 0 2 2 2 0 Nucleoporin FG repeat region PBP PF01161.20 EIM81695.1 - 2.6e-12 47.2 0.0 3.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 EIM81696.1 - 5.7e-12 46.1 0.0 6.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DDE_3 PF13358.6 EIM81697.1 - 3.4e-05 23.6 0.0 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease PBP PF01161.20 EIM81698.1 - 1.8e-08 34.8 0.0 2.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S9 PF00326.21 EIM81699.1 - 3.7e-39 134.4 0.0 5.5e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EIM81699.1 - 4.5e-06 26.4 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EIM81699.1 - 7.7e-06 25.7 0.1 0.04 13.5 0.0 3.0 2 1 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EIM81699.1 - 2.4e-05 23.7 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM81699.1 - 0.0022 17.7 0.0 0.17 11.5 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Fibrillarin_2 PF10113.9 EIM81699.1 - 0.0038 15.9 0.0 0.0059 15.3 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein BAAT_C PF08840.11 EIM81699.1 - 0.0046 16.9 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PQQ_3 PF13570.6 EIM81699.1 - 0.0075 16.7 1.7 0.028 14.9 0.3 2.7 2 0 0 2 2 2 1 PQQ-like domain Abhydrolase_4 PF08386.10 EIM81699.1 - 0.016 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 EIM81699.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 EIM81699.1 - 0.14 11.7 0.0 0.51 9.8 0.0 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase HrpE PF06188.12 EIM81699.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E FIST PF08495.10 EIM81701.1 - 8.3e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 FIST N domain CPBP PF02517.16 EIM81702.1 - 0.51 10.7 3.5 0.91 9.9 2.2 2.1 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease HCO3_cotransp PF00955.21 EIM81703.1 - 1.3e-77 261.8 5.3 5e-37 127.9 3.0 3.0 2 1 1 3 3 3 3 HCO3- transporter family Sulfate_transp PF00916.20 EIM81703.1 - 0.003 16.4 1.4 0.003 16.4 1.4 2.0 2 0 0 2 2 2 1 Sulfate permease family Abhydrolase_6 PF12697.7 EIM81704.1 - 6.5e-12 46.5 0.5 1e-11 45.9 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM81704.1 - 3.6e-08 33.0 0.1 4.9e-06 26.0 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM81704.1 - 1.6e-05 24.7 0.0 4.2e-05 23.3 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EIM81704.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM81704.1 - 0.00043 19.8 0.1 0.0041 16.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 EIM81704.1 - 0.02 14.6 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PHY PF00360.20 EIM81705.1 - 4e-24 84.9 0.0 7.6e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EIM81705.1 - 3.6e-21 75.8 0.1 2e-20 73.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM81705.1 - 2.1e-16 60.1 0.6 6.6e-16 58.5 0.6 1.9 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EIM81705.1 - 2.2e-13 51.0 0.0 9.5e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 EIM81705.1 - 2.7e-10 40.9 0.0 1.3e-09 38.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 EIM81705.1 - 9.2e-10 38.4 0.9 2.8e-09 36.9 0.9 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain p450 PF00067.22 EIM81706.1 - 1.7e-67 228.1 0.0 2.1e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EIM81707.1 - 2.2e-05 24.3 0.1 6.7e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like Glyco_hydro_92 PF07971.12 EIM81709.1 - 6.3e-114 381.4 0.2 1.6e-104 350.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EIM81709.1 - 1.3e-33 116.9 5.8 5.5e-23 82.1 0.9 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 N-terminal domain Tfb2 PF03849.14 EIM81709.1 - 0.075 12.0 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Transcription factor Tfb2 ETF PF01012.21 EIM81710.1 - 1.7e-36 125.8 0.3 2.3e-36 125.4 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Hydant_A_N PF05378.13 EIM81710.1 - 0.13 11.9 0.4 16 5.2 0.0 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase N-terminal region zf-RING_2 PF13639.6 EIM81711.1 - 1.6e-12 47.5 5.3 2.6e-12 46.9 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EIM81711.1 - 1.2e-09 37.7 1.9 2.2e-09 36.9 1.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EIM81711.1 - 2.9e-08 33.9 5.4 6.1e-08 32.8 5.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EIM81711.1 - 1e-07 31.7 4.5 1.6e-07 31.0 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM81711.1 - 1.1e-07 31.7 3.5 1.7e-07 31.1 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM81711.1 - 2.2e-07 30.6 4.5 3.4e-07 30.0 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM81711.1 - 3.1e-05 23.9 3.9 6e-05 23.0 3.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM81711.1 - 4.2e-05 23.3 2.9 7.3e-05 22.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM81711.1 - 0.00015 21.7 1.2 0.00032 20.7 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EIM81711.1 - 0.0004 20.2 2.8 0.0007 19.4 2.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EIM81711.1 - 0.0015 18.1 2.1 0.0026 17.3 2.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EIM81711.1 - 0.024 15.0 2.3 0.042 14.2 2.3 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EIM81711.1 - 0.028 14.2 5.1 0.048 13.5 5.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EIM81711.1 - 0.093 12.9 5.2 0.15 12.2 5.2 1.3 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 EIM81711.1 - 0.21 11.7 1.4 0.41 10.7 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_5 PF17121.5 EIM81711.1 - 0.37 10.7 3.6 0.38 10.7 2.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 EIM81711.1 - 0.9 9.7 5.3 2.2 8.4 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PHD PF00628.29 EIM81711.1 - 0.96 9.4 4.7 1.6 8.7 4.7 1.3 1 0 0 1 1 1 0 PHD-finger His_Phos_2 PF00328.22 EIM81713.1 - 4.2e-06 26.4 1.1 0.0014 18.1 0.0 2.5 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) Tyrosinase PF00264.20 EIM81714.1 - 1.9e-33 116.6 1.8 3e-33 116.0 1.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2189 PF09955.9 EIM81714.1 - 0.1 12.8 0.2 0.2 11.9 0.2 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) PhoR PF11808.8 EIM81715.1 - 0.37 11.2 12.9 0.6 10.6 0.7 3.6 4 1 1 5 5 5 0 Phosphate regulon sensor protein PhoR DUF4519 PF15012.6 EIM81715.1 - 1.4 9.2 5.3 20 5.5 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DIOX_N PF14226.6 EIM81716.1 - 1.3e-24 87.2 0.1 2e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM81716.1 - 4.4e-19 68.9 0.0 7.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily QWRF PF04484.12 EIM81718.1 - 2 8.1 8.4 2.9 7.6 8.4 1.2 1 0 0 1 1 1 0 QWRF family MFS_1 PF07690.16 EIM81719.1 - 8.7e-50 169.6 15.5 1.2e-49 169.1 15.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81719.1 - 4.7e-10 38.9 26.3 5.4e-09 35.4 8.0 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 EIM81719.1 - 3.3e-06 25.7 0.0 3.3e-06 25.7 0.0 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EIM81719.1 - 0.00013 21.0 0.4 0.00013 21.0 0.4 2.7 3 0 0 3 3 3 1 MFS_1 like family Ctr PF04145.15 EIM81719.1 - 0.075 13.6 0.7 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Ctr copper transporter family GST_N PF02798.20 EIM81720.1 - 2e-12 47.3 0.0 4.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM81720.1 - 2.6e-10 40.4 0.0 5.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIM81720.1 - 1.5e-08 34.9 0.0 3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81720.1 - 4.2e-08 33.4 0.0 7.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM81720.1 - 4.7e-06 26.5 0.1 1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM81720.1 - 4.8e-06 26.7 0.0 9.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Iwr1 PF08574.10 EIM81721.1 - 8.7e-11 42.7 5.9 8.7e-11 42.7 5.9 2.5 2 1 1 3 3 3 1 Transcription factor Iwr1 Homeodomain PF00046.29 EIM81722.1 - 0.0018 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain F-box-like PF12937.7 EIM81723.1 - 5.7e-06 26.1 0.2 1.4e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM81724.1 - 1.3e-05 25.0 1.9 4e-05 23.4 1.9 1.9 1 0 0 1 1 1 1 F-box-like Peptidase_M16 PF00675.20 EIM81725.1 - 3e-54 183.0 1.7 3.3e-54 182.9 0.6 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EIM81725.1 - 4e-39 134.5 0.0 9.2e-37 126.8 0.0 2.9 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_S78_2 PF14550.6 EIM81725.1 - 0.051 13.7 0.4 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Putative phage serine protease XkdF Striatin PF08232.12 EIM81725.1 - 0.079 13.6 0.1 0.24 12.0 0.0 1.8 2 0 0 2 2 2 0 Striatin family MTD PF01993.18 EIM81725.1 - 0.083 12.2 0.0 6.2 6.1 0.0 2.2 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase CoA_transf_3 PF02515.17 EIM81727.1 - 2.3e-36 125.7 0.2 1.1e-17 64.3 0.0 3.5 3 0 0 3 3 3 3 CoA-transferase family III zf-FCS PF06467.14 EIM81728.1 - 0.0022 17.9 4.4 0.71 9.9 0.1 2.7 2 1 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif CDC24_OB3 PF17244.2 EIM81728.1 - 0.035 13.8 4.3 0.037 13.7 4.3 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Opy2 PF09463.10 EIM81728.1 - 1.6 9.1 7.7 0.21 11.9 1.6 2.3 2 0 0 2 2 2 0 Opy2 protein zf-C2H2 PF00096.26 EIM81728.1 - 7.4 7.2 11.2 1.2 9.7 0.6 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ndc1_Nup PF09531.10 EIM81729.1 - 2.6 6.6 8.4 2.6 6.7 8.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 EIM81730.1 - 2e-68 230.6 0.0 2.6e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81730.1 - 2.6e-41 141.6 0.0 4.6e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM81730.1 - 2.5e-08 33.6 0.0 4.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM81730.1 - 0.023 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM81730.1 - 0.039 13.9 0.1 3.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EIM81730.1 - 0.067 12.8 0.1 0.15 11.6 0.1 1.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ndc1_Nup PF09531.10 EIM81730.1 - 0.57 8.8 3.7 0.62 8.7 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C2H2_jaz PF12171.8 EIM81731.1 - 2.5e-07 30.8 0.8 0.02 15.2 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EIM81731.1 - 3.7e-06 27.1 6.4 0.0023 18.3 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EIM81731.1 - 3.9e-05 23.5 4.5 0.0012 18.8 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EIM81731.1 - 0.00014 22.4 5.2 0.12 13.3 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EIM81731.1 - 0.0022 18.3 2.4 0.023 15.1 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 EIM81731.1 - 0.015 14.9 1.8 0.29 10.8 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RING_7 PF02591.15 EIM81731.1 - 0.092 12.9 1.9 7.7 6.8 0.2 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-H2C2_2 PF13465.6 EIM81731.1 - 0.13 12.7 0.4 0.13 12.7 0.4 3.1 3 0 0 3 3 2 0 Zinc-finger double domain zinc_ribbon_9 PF14369.6 EIM81731.1 - 0.17 12.2 2.0 0.21 11.9 0.1 2.2 2 0 0 2 2 1 0 zinc-ribbon zf-CHY PF05495.12 EIM81731.1 - 0.39 11.3 5.1 0.43 11.1 1.3 2.2 2 0 0 2 2 2 0 CHY zinc finger zinc-ribbons_6 PF07191.12 EIM81731.1 - 0.52 10.3 4.1 1.1 9.3 4.1 1.6 1 0 0 1 1 1 0 zinc-ribbons TFIIF_alpha PF05793.12 EIM81731.1 - 0.54 8.8 3.3 0.9 8.1 3.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DZR PF12773.7 EIM81731.1 - 8.3 6.5 8.0 53 4.0 8.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon Pectinesterase PF01095.19 EIM81732.1 - 6.8e-38 130.1 3.4 1.6e-31 109.2 1.3 2.0 2 0 0 2 2 2 2 Pectinesterase ParA PF10609.9 EIM81733.1 - 3.5e-75 252.6 0.0 1.1e-74 251.1 0.0 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EIM81733.1 - 1.6e-12 47.6 0.0 5.2e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EIM81733.1 - 1e-08 35.3 0.3 7.7e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EIM81733.1 - 1.6e-06 27.6 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EIM81733.1 - 0.00014 21.2 0.7 0.0017 17.6 0.2 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 EIM81733.1 - 0.005 16.4 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EIM81733.1 - 0.019 14.8 0.4 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 EIM81733.1 - 0.024 14.1 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 EIM81733.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Dynamin_N PF00350.23 EIM81734.1 - 1.4e-18 67.5 0.0 3.9e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EIM81734.1 - 5.6e-13 49.0 0.0 3.8e-12 46.3 0.0 2.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIM81734.1 - 1.7e-08 34.2 0.5 9.4e-08 31.8 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIM81734.1 - 0.00081 19.3 0.8 0.91 9.4 0.3 2.9 2 1 1 3 3 3 2 RsgA GTPase IIGP PF05049.13 EIM81734.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) cobW PF02492.19 EIM81734.1 - 0.012 15.2 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EIM81734.1 - 0.029 14.6 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EIM81734.1 - 0.03 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 EIM81734.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 EIM81734.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin HSP9_HSP12 PF04119.12 EIM81734.1 - 0.28 11.6 3.5 0.15 12.5 0.3 2.2 2 0 0 2 2 2 0 Heat shock protein 9/12 Syntaxin_2 PF14523.6 EIM81736.1 - 4.8e-23 81.4 5.1 7e-22 77.7 1.2 2.5 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EIM81736.1 - 2.4e-11 43.5 3.7 6.4e-11 42.1 1.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EIM81736.1 - 2.6e-06 27.2 8.7 7.8e-06 25.7 8.7 1.8 1 1 0 1 1 1 1 Syntaxin TMPIT PF07851.13 EIM81736.1 - 0.0049 16.2 1.0 0.012 14.9 0.2 1.8 1 1 1 2 2 2 1 TMPIT-like protein Synaptobrevin PF00957.21 EIM81736.1 - 0.071 12.9 0.1 0.28 11.0 0.1 2.1 1 0 0 1 1 1 0 Synaptobrevin Prominin PF05478.11 EIM81736.1 - 0.15 10.0 4.9 0.23 9.4 4.9 1.3 1 1 0 1 1 1 0 Prominin FlaC_arch PF05377.11 EIM81736.1 - 0.41 11.1 2.1 36 4.8 0.0 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Orf78 PF06024.12 EIM81736.1 - 0.9 9.9 3.0 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Halogen_Hydrol PF10112.9 EIM81736.1 - 5.1 7.1 6.5 1 9.3 0.2 2.7 3 1 1 4 4 4 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DAO PF01266.24 EIM81737.1 - 7e-51 173.9 0.0 1e-50 173.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EIM81737.1 - 1.4e-46 157.4 0.9 2.3e-46 156.8 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EIM81737.1 - 2.3e-07 30.3 2.0 0.0008 18.6 0.4 2.5 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EIM81737.1 - 1.7e-05 24.4 1.8 0.00018 21.0 0.7 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIM81737.1 - 2e-05 24.0 0.1 0.00011 21.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM81737.1 - 3e-05 23.4 0.4 0.00016 21.1 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM81737.1 - 0.015 15.5 0.2 0.046 14.0 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EIM81737.1 - 0.032 13.3 0.1 0.13 11.3 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EIM81737.1 - 0.036 13.9 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EIM81737.1 - 0.048 12.9 0.1 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM81737.1 - 0.054 12.5 0.1 2.3 7.2 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 EIM81737.1 - 0.12 13.0 1.4 0.21 12.2 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM81737.1 - 0.14 10.9 1.0 0.24 10.1 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein AMP-binding PF00501.28 EIM81740.1 - 4.5e-79 266.0 0.0 5.6e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM81740.1 - 0.00064 20.7 0.0 0.0022 18.9 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Meth_synt_2 PF01717.18 EIM81742.1 - 1.8e-12 47.2 0.0 1.3e-06 27.9 0.0 2.7 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIM81742.1 - 0.016 14.8 0.0 0.066 12.7 0.0 1.9 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.18 EIM81743.1 - 6.2e-15 55.3 0.0 5.6e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIM81743.1 - 2.3e-06 27.4 0.0 0.0052 16.3 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Ysc84 PF04366.12 EIM81745.1 - 5.1e-46 155.6 0.0 8.3e-46 154.9 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Phosphodiest PF01663.22 EIM81746.1 - 1.5e-79 268.2 3.1 1.9e-79 267.8 3.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EIM81746.1 - 0.041 13.3 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Sulfatase Lipase_GDSL_2 PF13472.6 EIM81747.1 - 4.5e-09 36.9 0.0 8.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIM81747.1 - 0.00012 22.1 0.0 0.001 19.1 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 EIM81747.1 - 0.0064 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Pkinase PF00069.25 EIM81748.1 - 4.7e-73 245.8 0.0 6.4e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81748.1 - 1.4e-34 119.5 0.0 2.7e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM81748.1 - 0.00047 19.2 0.0 0.022 13.7 0.0 2.7 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EIM81748.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM81748.1 - 0.061 13.2 0.3 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family CHAT PF12770.7 EIM81749.1 - 2.2e-28 99.5 2.0 2.9e-28 99.1 0.3 2.1 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 EIM81749.1 - 0.0068 16.2 4.2 1.5 8.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM81749.1 - 0.069 13.0 0.0 30 4.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 EIM81749.1 - 0.13 11.4 0.0 0.59 9.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C50 MFS_1 PF07690.16 EIM81751.1 - 9e-39 133.4 44.7 6.3e-35 120.7 21.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81751.1 - 1.9e-16 60.0 9.6 3.8e-16 59.0 9.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EIM81751.1 - 7.6e-05 21.7 13.2 0.0093 14.9 4.6 2.2 1 1 1 2 2 2 2 MFS_1 like family TRI12 PF06609.13 EIM81751.1 - 0.00011 20.8 1.6 0.00022 19.8 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Q_salvage PF10343.9 EIM81752.1 - 4.4e-96 321.8 0.0 5.6e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family SNF5 PF04855.12 EIM81753.1 - 2.9e-73 246.6 0.1 8.3e-73 245.1 0.1 1.7 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DNA_pol_B_thumb PF14791.6 EIM81754.1 - 9.4e-14 51.3 0.2 5.6e-13 48.9 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EIM81754.1 - 9.9e-14 51.5 0.0 9.5e-06 25.8 0.0 2.7 3 0 0 3 3 3 2 DNA polymerase beta palm HHH_8 PF14716.6 EIM81754.1 - 5.3e-12 45.9 0.4 8.8e-11 42.0 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EIM81754.1 - 1.3e-11 44.2 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 EIM81754.1 - 0.00023 21.3 0.7 0.00057 20.1 0.0 2.0 3 0 0 3 3 3 1 Pathogenicity locus HHH_5 PF14520.6 EIM81754.1 - 0.00034 21.2 0.4 0.025 15.2 0.0 2.9 1 1 1 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EIM81754.1 - 0.006 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_3 PF12836.7 EIM81754.1 - 0.0079 16.4 0.0 1.3 9.3 0.1 2.4 1 1 1 2 2 2 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 EIM81754.1 - 0.023 15.0 0.3 19 5.8 0.0 3.7 3 0 0 3 3 3 0 IMS family HHH motif WD40 PF00400.32 EIM81755.1 - 3.3e-94 306.2 41.8 9.3e-10 39.0 0.1 14.4 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM81755.1 - 6.4e-38 128.9 0.1 4.3e-05 23.7 0.0 11.0 3 3 8 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain DUF2235 PF09994.9 EIM81755.1 - 4.2e-26 92.0 0.2 2.1e-12 47.0 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ge1_WD40 PF16529.5 EIM81755.1 - 7.2e-10 38.3 5.1 0.035 13.1 0.0 7.6 2 2 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM81755.1 - 5.4e-09 35.8 0.0 0.093 12.0 0.0 5.6 5 3 1 6 6 6 2 WD40-like domain PQQ_2 PF13360.6 EIM81755.1 - 2.1e-07 30.8 4.1 0.0067 16.0 2.3 4.4 2 1 1 3 3 3 1 PQQ-like domain PD40 PF07676.12 EIM81755.1 - 2.2e-06 27.5 1.9 0.72 9.9 0.1 6.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EIM81755.1 - 6.1e-06 25.2 2.6 1 7.9 0.0 6.9 5 2 3 9 9 9 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EIM81755.1 - 0.00024 21.1 0.0 23 5.1 0.0 5.8 6 1 1 7 7 7 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 EIM81755.1 - 0.0043 16.9 0.1 6.3 6.9 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat Nucleoporin_N PF08801.11 EIM81755.1 - 0.0063 15.3 5.5 1.2 7.8 0.2 5.0 3 2 3 6 6 6 1 Nup133 N terminal like LRR_6 PF13516.6 EIM81756.1 - 3.2e-15 54.8 11.5 0.086 12.9 0.0 7.7 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EIM81756.1 - 4.4e-09 36.5 11.1 0.071 13.6 0.2 6.5 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIM81756.1 - 5.3e-05 23.2 4.9 30 5.7 0.1 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 EIM81756.1 - 0.0069 16.1 13.6 1.1 9.1 0.8 5.2 4 2 0 4 4 4 2 Leucine rich repeat DUF604 PF04646.12 EIM81756.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DUF3391 PF11871.8 EIM81756.1 - 0.12 13.0 1.6 0.22 12.0 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3605 PF12239.8 EIM81757.1 - 5.5e-27 95.0 0.2 9.8e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) zf-CHY PF05495.12 EIM81759.1 - 3.6e-14 53.0 14.7 8.3e-14 51.8 14.7 1.6 1 1 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 EIM81759.1 - 0.014 15.2 6.1 1.1 9.1 0.1 2.7 1 1 1 2 2 2 0 Cysteine-rich KTR HypA PF01155.19 EIM81759.1 - 0.022 14.8 1.8 0.022 14.8 1.8 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3797 PF12677.7 EIM81759.1 - 0.027 14.3 3.7 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Zn-ribbon_8 PF09723.10 EIM81759.1 - 0.03 14.4 2.8 0.03 14.4 2.8 2.5 2 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 EIM81759.1 - 0.051 13.5 12.6 1.3 9.0 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 EIM81759.1 - 0.062 13.2 0.3 0.062 13.2 0.3 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EIM81759.1 - 0.11 12.5 11.6 4.9 7.2 7.7 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.12 EIM81759.1 - 0.14 12.4 12.6 1 9.7 0.4 3.2 1 1 2 3 3 3 0 TFIIH C1-like domain DpnI PF06044.12 EIM81759.1 - 1 9.0 5.8 9.1 5.9 1.6 2.0 1 1 1 2 2 2 0 Dam-replacing family zf-C2HC5 PF06221.13 EIM81759.1 - 1.1 9.4 8.4 0.042 13.8 2.4 1.9 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Anti-TRAP PF15777.5 EIM81759.1 - 1.4 9.0 5.2 0.74 9.8 0.1 2.3 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Evr1_Alr PF04777.13 EIM81759.1 - 1.8 9.1 7.8 14 6.2 7.8 2.4 1 1 0 1 1 1 0 Erv1 / Alr family zinc_ribbon_10 PF10058.9 EIM81759.1 - 2.1 8.1 9.4 0.28 10.9 1.6 2.4 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4379 PF14311.6 EIM81759.1 - 2.3 8.7 12.1 0.23 11.8 1.0 2.4 1 1 0 2 2 2 0 Probable Zinc-ribbon domain zinc_ribbon_9 PF14369.6 EIM81759.1 - 2.9 8.2 12.7 0.82 10.0 3.1 3.2 1 1 2 3 3 3 0 zinc-ribbon zinc_ribbon_2 PF13240.6 EIM81759.1 - 9.1 6.1 12.2 2.4 8.0 0.5 3.2 3 0 0 3 3 3 0 zinc-ribbon domain MCM_OB PF17207.3 EIM81759.1 - 9.5 6.1 7.3 1 9.2 1.8 2.1 1 1 1 2 2 2 0 MCM OB domain Mob1_phocein PF03637.17 EIM81760.1 - 4.3e-68 228.6 0.8 5.2e-68 228.3 0.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans PF04082.18 EIM81762.1 - 2.3e-14 53.1 0.7 3.8e-14 52.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM81762.1 - 1.4e-07 31.5 10.2 3.5e-07 30.2 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 EIM81762.1 - 0.00056 20.2 2.1 0.00056 20.2 2.1 3.8 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 EIM81762.1 - 0.0019 18.6 3.5 0.0019 18.6 3.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM81762.1 - 0.0072 17.1 2.5 0.0072 17.1 2.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-MYST PF17772.1 EIM81762.1 - 0.14 11.8 3.6 0.32 10.6 0.7 2.4 1 1 1 2 2 2 0 MYST family zinc finger domain Flavoprotein PF02441.19 EIM81763.1 - 1.3e-53 181.0 0.0 1.4e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Pex24p PF06398.11 EIM81764.1 - 1.9e-20 73.2 9.7 1.9e-20 73.2 9.7 2.2 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin PRT_C PF08372.10 EIM81764.1 - 0.73 9.6 3.8 14 5.4 0.2 2.4 2 1 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal AA_permease PF00324.21 EIM81765.1 - 1.3e-109 367.0 45.3 1.6e-109 366.7 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM81765.1 - 3.1e-34 118.5 47.6 4e-34 118.2 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease zf-RING_2 PF13639.6 EIM81767.1 - 3.2e-05 24.2 5.6 5e-05 23.6 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM81767.1 - 0.0074 16.1 3.8 0.012 15.5 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM81767.1 - 0.024 14.5 5.4 0.039 13.8 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM81767.1 - 0.11 12.4 6.8 0.17 11.8 6.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM81767.1 - 0.16 12.0 3.5 0.57 10.3 3.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EIM81767.1 - 0.31 10.9 5.4 0.55 10.1 2.9 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain tRNA_int_end_N2 PF12928.7 EIM81768.1 - 6.2e-20 71.2 0.0 1.1e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EIM81768.1 - 0.034 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Glyco_hydro_18 PF00704.28 EIM81769.1 - 9.1e-15 55.2 1.1 1.2e-14 54.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 EIM81769.1 - 0.0078 16.7 1.5 0.0078 16.7 1.5 3.3 3 0 0 3 3 3 1 Carbohydrate binding domain F-box-like PF12937.7 EIM81770.1 - 0.00011 22.1 0.0 0.0004 20.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like MFS_1 PF07690.16 EIM81771.1 - 5.4e-33 114.4 20.4 1.2e-32 113.3 19.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81771.1 - 6.5e-06 25.3 16.9 1.1e-05 24.5 7.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter UPF0060 PF02694.15 EIM81771.1 - 0.051 13.8 0.3 0.051 13.8 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF1772 PF08592.11 EIM81771.1 - 5.2 7.4 8.1 0.51 10.7 0.3 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Lactamase_B_2 PF12706.7 EIM81772.1 - 7.4e-33 113.8 0.2 3.8e-32 111.4 0.2 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EIM81772.1 - 4.7e-10 39.6 0.0 1.7e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM81772.1 - 0.0018 18.3 0.5 0.022 14.8 0.0 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 EIM81773.1 - 7.1e-11 41.6 77.2 1.8e-09 37.0 35.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MP PF01107.18 EIM81773.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) adh_short PF00106.25 EIM81774.1 - 1.6e-19 70.1 0.0 3.2e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81774.1 - 4.1e-12 46.2 0.0 7.9e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81774.1 - 2e-08 34.4 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM81774.1 - 7.4e-05 22.3 0.0 0.0001 21.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81774.1 - 0.0028 17.1 0.0 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 EIM81774.1 - 0.006 16.0 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 EIM81774.1 - 0.053 13.1 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_7 PF13241.6 EIM81774.1 - 0.062 13.7 0.3 0.14 12.6 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 EIM81774.1 - 0.16 11.1 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SKN1 PF03935.15 EIM81775.1 - 4.1e-182 606.1 11.7 4.6e-182 605.9 11.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sas10 PF09368.10 EIM81776.1 - 1.6e-26 92.5 4.4 1.6e-26 92.5 4.4 3.5 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EIM81776.1 - 7.3e-05 23.3 1.0 7.3e-05 23.3 1.0 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Peroxidase_ext PF11895.8 EIM81778.1 - 6.7e-27 93.2 1.1 1.6e-26 92.0 0.6 2.0 2 0 0 2 2 2 1 Fungal peroxidase extension region peroxidase PF00141.23 EIM81778.1 - 6.3e-26 91.5 0.0 1.7e-25 90.1 0.0 1.7 1 1 1 2 2 2 1 Peroxidase Peroxidase_ext PF11895.8 EIM81779.1 - 1.8e-26 91.8 1.5 5.1e-26 90.4 1.5 1.8 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 EIM81779.1 - 5.2e-25 88.5 0.3 8.4e-25 87.8 0.0 1.5 2 0 0 2 2 2 1 Peroxidase Glyco_hydro_28 PF00295.17 EIM81780.1 - 5.7e-25 88.0 0.6 8.4e-25 87.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EIM81780.1 - 0.0007 19.5 7.7 0.0012 18.7 0.7 2.8 1 1 0 2 2 2 2 Pectate lyase superfamily protein Arm PF00514.23 EIM81785.1 - 5.1e-07 29.5 0.1 0.0087 16.1 0.1 3.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 EIM81786.1 - 2.6e-07 30.3 0.0 2.9e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM81786.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase YukC PF10140.9 EIM81786.1 - 0.25 10.1 0.0 0.26 10.1 0.0 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ADH_N PF08240.12 EIM81787.1 - 4.7e-21 74.7 3.8 1.1e-20 73.5 3.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM81787.1 - 1.4e-13 50.9 0.2 8.2e-13 48.5 0.1 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM81787.1 - 0.00087 20.3 0.0 0.0017 19.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EIM81787.1 - 0.097 12.1 1.1 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase ThrE PF06738.12 EIM81788.1 - 3.6e-51 173.9 22.5 5e-50 170.1 7.9 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM81788.1 - 2.5e-10 40.6 6.9 2.5e-10 40.6 6.9 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Methyltransf_25 PF13649.6 EIM81789.1 - 0.047 14.4 0.0 4.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain adh_short_C2 PF13561.6 EIM81791.1 - 6.2e-29 101.2 0.1 6.2e-29 101.2 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM81791.1 - 1.1e-23 83.7 0.6 4.7e-22 78.4 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM81791.1 - 1.3e-05 25.2 0.3 9.8e-05 22.3 0.3 2.2 1 1 0 1 1 1 1 KR domain RNA_lig_T4_1 PF09511.10 EIM81792.1 - 1.4e-83 280.1 0.0 2.6e-83 279.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EIM81792.1 - 2e-24 86.6 0.0 3.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EIM81792.1 - 1.1e-20 74.1 0.0 2.9e-20 72.8 0.0 1.6 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain p450 PF00067.22 EIM81797.1 - 3.2e-66 224.0 0.0 3.6e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_67M PF07488.12 EIM81797.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain p450 PF00067.22 EIM81798.1 - 1.2e-66 225.4 0.0 1.5e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prp18 PF02840.15 EIM81798.1 - 0.099 12.7 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 Prp18 domain NAD_binding_4 PF07993.12 EIM81799.1 - 1.3e-35 122.9 0.0 1.8e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM81799.1 - 1e-28 100.1 0.0 1.2e-27 96.6 0.0 2.6 4 0 0 4 4 4 1 AMP-binding enzyme Epimerase PF01370.21 EIM81799.1 - 2.6e-07 30.3 0.0 5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM81799.1 - 0.00054 20.3 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EIM81799.1 - 0.041 13.0 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 EIM81800.1 - 9e-23 80.7 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM81800.1 - 2.9e-16 59.3 0.0 5.4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EIM81800.1 - 4.6e-08 34.2 0.0 8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EIM81800.1 - 0.036 13.5 0.1 0.14 11.6 0.1 1.8 1 1 0 1 1 1 0 short chain dehydrogenase GMC_oxred_N PF00732.19 EIM81801.1 - 1.9e-46 158.8 0.0 3.4e-40 138.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM81801.1 - 3.1e-30 105.6 0.0 6.7e-30 104.5 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase DUF1943 PF09172.11 EIM81803.1 - 0.011 14.9 8.6 0.016 14.4 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF916 PF06030.12 EIM81803.1 - 0.075 13.1 8.6 0.41 10.7 0.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) NMD3 PF04981.13 EIM81803.1 - 0.18 11.3 8.1 0.31 10.4 8.1 1.3 1 0 0 1 1 1 0 NMD3 family Glyco_hydro_2 PF00703.21 EIM81803.1 - 0.25 12.1 6.2 0.53 11.0 6.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 LEA_2 PF03168.13 EIM81803.1 - 0.48 11.0 13.9 34 5.1 13.9 2.4 1 1 0 1 1 1 0 Late embryogenesis abundant protein CBM_4_9 PF02018.17 EIM81803.1 - 2 8.7 11.3 2.9e+02 1.7 11.3 2.2 1 1 0 1 1 1 0 Carbohydrate binding domain DUF3156 PF11354.8 EIM81803.1 - 4.7 7.1 5.1 24 4.8 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3156) MFS_1 PF07690.16 EIM81804.1 - 4.1e-28 98.3 49.3 4.1e-28 98.3 49.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EIM81805.1 - 1.6e-34 119.4 0.0 2.9e-34 118.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 EIM81806.1 - 3.2e-24 85.6 12.5 4e-24 85.3 12.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 EIM81807.1 - 5.8e-52 177.0 0.0 1.2e-51 175.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 EIM81808.1 - 4.4e-60 203.4 0.1 5.8e-60 203.0 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 EIM81809.1 - 7.1e-19 68.3 0.0 9.3e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM81809.1 - 7.5e-08 32.5 0.0 6.8e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EIM81809.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EIM81809.1 - 0.015 15.6 0.1 0.035 14.3 0.0 1.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EIM81809.1 - 0.04 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EIM81809.1 - 0.17 12.5 0.1 0.5 11.0 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CHAT PF12770.7 EIM81810.1 - 1.6e-22 80.3 0.1 2.1e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 CHAT domain SHIPPO-rpt PF07004.12 EIM81814.1 - 0.049 14.6 0.0 0.11 13.5 0.0 1.6 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat ANAPC4_WD40 PF12894.7 EIM81816.1 - 0.00093 19.5 0.0 0.11 12.8 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM81816.1 - 0.019 15.8 0.0 0.52 11.3 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat adh_short PF00106.25 EIM81817.1 - 5.4e-28 97.8 0.0 1.6e-25 89.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81817.1 - 1.8e-14 53.9 0.0 3e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81817.1 - 8.9e-09 35.5 0.2 2e-08 34.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EIM81817.1 - 1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81817.1 - 4.6e-06 26.3 0.1 1.3e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM81817.1 - 0.0013 18.0 0.1 0.0059 15.8 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EIM81817.1 - 0.016 14.3 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 EIM81817.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PAC1 PF16094.5 EIM81817.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 3Beta_HSD PF01073.19 EIM81817.1 - 0.21 10.6 0.0 0.58 9.1 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DER1 PF04511.15 EIM81819.1 - 1 9.2 11.0 0.22 11.4 1.1 2.7 2 1 1 3 3 3 0 Der1-like family adh_short PF00106.25 EIM81820.1 - 1.3e-28 99.8 0.1 9.6e-25 87.2 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81820.1 - 2.2e-18 66.7 0.1 5.3e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81820.1 - 1.8e-08 34.5 0.0 3.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM81820.1 - 8.7e-07 28.6 0.1 1.2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EIM81820.1 - 0.00027 20.2 0.1 0.00031 20.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EIM81820.1 - 0.012 15.0 0.3 0.1 12.0 0.3 2.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase SMC_hinge PF06470.13 EIM81820.1 - 0.017 15.4 0.1 0.051 13.9 0.1 1.8 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Sacchrp_dh_NADP PF03435.18 EIM81820.1 - 0.048 13.9 0.3 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EIM81820.1 - 0.08 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EIM81821.1 - 3.1e-27 95.3 0.0 3e-23 82.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81821.1 - 1.7e-16 60.5 0.0 2.8e-13 50.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81821.1 - 5.3e-08 33.0 0.4 1.1e-07 31.9 0.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM81821.1 - 0.0015 18.0 0.3 0.0024 17.4 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM81821.1 - 0.027 13.9 0.1 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 EIM81821.1 - 0.036 14.5 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 EIM81821.1 - 0.049 12.8 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EIM81821.1 - 0.066 12.4 0.4 0.15 11.2 0.4 1.5 1 1 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 EIM81821.1 - 0.16 10.9 0.1 0.3 10.0 0.0 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EIM81822.1 - 1.5e-30 106.1 0.2 1e-23 83.8 0.2 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81822.1 - 6.2e-16 58.7 0.5 4.5e-13 49.3 0.3 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM81822.1 - 7.8e-10 38.6 0.1 9.9e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM81822.1 - 1.8e-09 37.8 0.3 3.4e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM81822.1 - 1.7e-06 27.4 0.1 2.3e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EIM81822.1 - 1.9e-06 27.5 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EIM81822.1 - 0.0083 16.4 0.1 0.022 15.0 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EIM81822.1 - 0.067 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding GFO_IDH_MocA PF01408.22 EIM81823.1 - 4.3e-12 46.9 0.0 1.3e-11 45.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 EIM81823.1 - 0.0051 16.5 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AAA_16 PF13191.6 EIM81824.1 - 4.9e-09 36.8 0.2 1.8e-08 35.0 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain C2 PF00168.30 EIM81824.1 - 4.5e-08 33.3 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain AAA_22 PF13401.6 EIM81824.1 - 1.8e-05 25.0 0.0 0.0004 20.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EIM81824.1 - 0.00046 20.1 0.0 0.0018 18.2 0.0 1.9 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EIM81824.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EIM81824.1 - 0.028 13.6 0.0 0.18 10.9 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.14 EIM81824.1 - 0.031 14.3 0.1 2.9 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 EIM81824.1 - 0.051 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Torsin DUF2075 PF09848.9 EIM81824.1 - 0.08 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) End_beta_propel PF12217.8 EIM81824.1 - 0.11 11.1 0.1 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Catalytic beta propeller domain of bacteriophage endosialidase AAA_18 PF13238.6 EIM81824.1 - 0.13 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EIM81824.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 EIM81824.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase SOG2 PF10428.9 EIM81825.1 - 0.065 12.4 5.7 0.093 11.9 5.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Aldedh PF00171.22 EIM81826.1 - 4.2e-182 605.8 0.2 4.7e-182 605.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 EIM81827.1 - 3.7e-182 605.9 0.1 4.2e-182 605.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5133 PF17196.4 EIM81827.1 - 1.4 9.2 3.0 1 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) SKG6 PF08693.10 EIM81828.1 - 4e-06 26.1 0.3 7.5e-06 25.3 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain UPF0203 PF05254.12 EIM81829.1 - 8.3e-26 90.0 2.1 1.1e-25 89.7 2.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 EIM81829.1 - 0.069 13.4 3.3 0.86 9.8 0.6 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 EIM81829.1 - 0.12 12.7 0.7 2.6 8.4 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Metallophos_2 PF12850.7 EIM81830.1 - 5.2e-18 65.8 0.2 7.5e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EIM81830.1 - 2.8e-08 34.5 0.7 0.0034 17.9 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Zn_clus PF00172.18 EIM81831.1 - 9e-09 35.3 11.4 9e-09 35.3 11.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Robl_LC7 PF03259.17 EIM81833.1 - 2.5e-10 40.0 0.0 1.4e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 Roadblock/LC7 domain Atg14 PF10186.9 EIM81834.1 - 3.5e-44 151.2 0.0 4.8e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Pex14_N PF04695.13 EIM81834.1 - 0.3 11.7 13.1 0.37 11.4 0.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like PF12937.7 EIM81835.1 - 3.1e-12 46.2 0.9 7.6e-12 44.9 0.9 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM81835.1 - 0.01 16.2 2.5 1.7 9.2 0.0 4.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) p450 PF00067.22 EIM81836.1 - 4e-65 220.4 0.0 5e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNase_PH PF01138.21 EIM81838.1 - 9.1e-29 100.6 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EIM81838.1 - 2.3e-05 24.3 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mago-bind PF09282.10 EIM81838.1 - 0.036 13.9 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 Mago binding BTB PF00651.31 EIM81839.1 - 1.1e-14 54.6 0.9 1.5e-06 28.4 0.1 3.2 3 0 0 3 3 3 2 BTB/POZ domain DUF3437 PF11919.8 EIM81839.1 - 0.013 15.3 0.3 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) F-box-like PF12937.7 EIM81840.1 - 6e-10 38.9 1.0 1.6e-09 37.5 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81840.1 - 0.025 14.4 0.1 0.11 12.4 0.1 2.2 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.7 EIM81840.1 - 0.25 11.8 2.5 76 3.9 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Pput2613-deam PF14427.6 EIM81841.1 - 0.2 11.5 0.6 0.78 9.7 0.0 2.0 2 0 0 2 2 2 0 Pput_2613-like deaminase Med27 PF11571.8 EIM81841.1 - 0.24 11.8 1.8 2.3 8.6 0.1 2.4 1 1 1 2 2 2 0 Mediator complex subunit 27 F-box-like PF12937.7 EIM81844.1 - 4.4e-09 36.1 0.9 8.3e-09 35.2 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81844.1 - 0.12 12.3 0.9 0.31 11.0 0.9 1.7 1 1 0 1 1 1 0 F-box domain RVT_thumb PF06817.14 EIM81844.1 - 0.13 12.1 0.1 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase thumb domain Adeno_PX PF05829.12 EIM81845.1 - 2.9 7.8 5.6 1.7 8.6 1.1 2.1 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) O-FucT PF10250.9 EIM81846.1 - 8.1e-07 29.0 0.0 3.2e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HSDR_N_2 PF13588.6 EIM81847.1 - 0.028 14.4 0.4 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) RGS_DHEX PF18148.1 EIM81847.1 - 1.3 9.2 5.8 0.98 9.6 1.5 2.2 1 1 0 2 2 2 0 Regulator of G-protein signalling DHEX domain Peptidase_M36 PF02128.15 EIM81848.1 - 3.8e-140 467.3 11.4 5.4e-140 466.8 11.4 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EIM81848.1 - 0.0031 17.3 0.2 0.0091 15.8 0.2 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF1202 PF06717.11 EIM81848.1 - 0.025 14.0 0.6 0.039 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) F-box PF00646.33 EIM81849.1 - 5.4e-07 29.3 2.3 1.2e-06 28.2 2.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM81849.1 - 0.00026 20.8 1.2 0.00068 19.5 1.2 1.8 1 0 0 1 1 1 1 F-box-like CBM-like PF14683.6 EIM81850.1 - 1.2e-22 80.5 0.0 2.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EIM81850.1 - 6.1e-19 67.6 0.1 1.5e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EIM81850.1 - 0.0021 18.3 0.1 0.0076 16.5 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.13 EIM81850.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Y_Y_Y domain BTB PF00651.31 EIM81851.1 - 6.9e-07 29.5 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3437 PF11919.8 EIM81851.1 - 0.14 12.0 0.3 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) BTB PF00651.31 EIM81852.1 - 9.3e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SMC_N PF02463.19 EIM81853.1 - 2.3e-21 76.3 0.0 3.8e-21 75.6 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIM81853.1 - 9e-20 72.0 0.0 9e-20 72.0 0.0 6.0 3 2 1 4 4 2 1 AAA domain AAA_29 PF13555.6 EIM81853.1 - 0.00035 20.3 0.0 0.00093 18.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EIM81853.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 3.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM81853.1 - 0.0016 18.2 12.0 0.0016 18.2 12.0 4.1 2 2 0 2 2 1 1 AAA ATPase domain DUF4201 PF13870.6 EIM81853.1 - 0.0063 16.3 9.5 0.0063 16.3 9.5 5.9 5 1 1 6 6 6 1 Domain of unknown function (DUF4201) AAA PF00004.29 EIM81853.1 - 0.017 15.5 0.1 0.37 11.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TPR_12 PF13424.6 EIM81853.1 - 0.059 13.7 0.4 0.059 13.7 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM81853.1 - 0.069 13.1 0.9 0.35 10.8 0.9 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM81853.1 - 0.17 12.1 0.8 1.1 9.6 0.8 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat GST_C_2 PF13410.6 EIM81853.1 - 0.59 10.2 2.1 8.4 6.5 0.0 3.6 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM81853.1 - 3.2 8.0 5.0 5.4 7.3 0.2 3.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain G-alpha PF00503.20 EIM81854.1 - 1.6e-103 346.6 0.0 1.9e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM81854.1 - 2.3e-12 46.7 0.2 1.5e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EIM81854.1 - 0.0071 16.6 0.0 5.5 7.2 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EIM81854.1 - 0.031 13.6 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.27 EIM81854.1 - 0.036 13.6 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EIM81854.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EIM81854.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.16 EIM81854.1 - 0.21 10.9 0.4 14 4.9 0.0 2.3 2 0 0 2 2 2 0 AIG1 family BTB PF00651.31 EIM81855.1 - 5.8e-08 32.9 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain EHN PF06441.12 EIM81855.1 - 0.039 14.3 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus BTB PF00651.31 EIM81856.1 - 4.2e-06 27.0 0.0 8.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM81857.1 - 1.6e-06 28.3 0.0 1.4e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Apc13p PF05839.11 EIM81857.1 - 0.066 13.4 0.0 4.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Apc13p protein Trp_DMAT PF11991.8 EIM81858.1 - 2.3e-50 172.0 0.0 5.1e-50 170.9 0.0 1.5 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase p450 PF00067.22 EIM81859.1 - 2.4e-73 247.5 0.0 2.9e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 EIM81860.1 - 8.8e-67 225.6 0.0 1.2e-66 225.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM81860.1 - 6.6e-27 94.8 0.1 1.1e-26 94.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM81860.1 - 0.00035 19.7 0.1 0.00053 19.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EIM81860.1 - 0.00072 19.7 0.6 0.0018 18.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM81860.1 - 0.0018 17.5 0.1 0.017 14.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM81860.1 - 0.025 13.8 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EIM81860.1 - 0.063 12.0 0.1 0.093 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 EIM81860.1 - 0.068 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EIM81860.1 - 0.086 13.1 0.1 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 EIM81860.1 - 0.12 11.4 0.4 0.25 10.4 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Chs7 PF12271.8 EIM81861.1 - 8.9e-80 268.1 10.9 1e-79 267.9 10.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF1582 PF07621.11 EIM81867.1 - 0.011 15.6 0.1 0.05 13.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) SOG2 PF10428.9 EIM81867.1 - 0.31 10.2 26.8 0.017 14.4 21.8 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein DUF3886 PF13025.6 EIM81867.1 - 1.2 9.4 10.5 0.78 10.0 3.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) VirionAssem_T7 PF11653.8 EIM81867.1 - 2.1 8.9 4.8 0.45 11.1 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein GPP34 PF05719.11 EIM81868.1 - 6.2e-68 228.8 0.9 7.5e-68 228.6 0.9 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF3445 PF11927.8 EIM81869.1 - 8.1e-72 241.5 0.0 9.8e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PTP_tm PF18861.1 EIM81871.1 - 0.0045 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J adh_short PF00106.25 EIM81872.1 - 1.7e-26 92.9 0.0 6e-25 87.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81872.1 - 3.1e-19 69.5 0.0 3.8e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81872.1 - 5.1e-09 36.3 0.1 7.2e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM81872.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EIM81872.1 - 0.0087 15.2 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EIM81872.1 - 0.049 13.5 0.1 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 EIM81872.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain UDG PF03167.19 EIM81873.1 - 1e-15 58.0 0.0 4.5e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Sec63 PF02889.16 EIM81874.1 - 1.1e-160 532.7 0.0 1.2e-89 299.9 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EIM81874.1 - 2e-48 164.5 0.1 2.5e-26 92.5 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EIM81874.1 - 2.1e-35 121.3 0.0 6.7e-35 119.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EIM81874.1 - 1.6e-24 86.8 0.1 4.1e-15 56.2 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM81874.1 - 4.4e-15 56.0 0.0 3.8e-08 33.7 0.0 3.8 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EIM81874.1 - 8.8e-07 29.3 0.0 0.044 14.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EIM81874.1 - 0.00055 19.5 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Helicase_C_2 PF13307.6 EIM81874.1 - 0.0037 17.4 0.3 4.6 7.4 0.0 3.9 3 1 1 4 4 4 1 Helicase C-terminal domain T2SSE PF00437.20 EIM81874.1 - 0.0041 16.2 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 EIM81874.1 - 0.0077 15.8 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region SET PF00856.28 EIM81875.1 - 2.3e-11 44.4 4.3 6e-11 43.0 0.2 2.4 1 1 1 2 2 2 1 SET domain preSET_CXC PF18264.1 EIM81875.1 - 2.9e-09 37.2 20.5 2.9e-09 37.2 20.5 4.4 3 1 1 4 4 4 2 CXC domain TCR PF03638.15 EIM81875.1 - 3.4 8.0 49.1 0.086 13.2 17.5 3.8 4 0 0 4 4 4 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain CBFD_NFYB_HMF PF00808.23 EIM81876.1 - 9.1e-27 93.1 0.3 1.3e-26 92.6 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM81876.1 - 8.6e-05 22.9 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIM81876.1 - 0.0038 17.3 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EIM81876.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EIM81876.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.32 EIM81877.1 - 2.1e-07 31.5 4.8 0.33 11.9 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.11 EIM81877.1 - 1.3e-06 28.3 0.0 1.3e-06 28.3 0.0 3.3 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) ATP_bind_1 PF03029.17 EIM81879.1 - 2.4e-75 253.4 0.0 2.9e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TMEM132D_C PF15706.5 EIM81880.1 - 5.3 6.9 5.0 4.8 7.0 0.2 2.5 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DEAD PF00270.29 EIM81881.1 - 2.2e-14 53.6 0.0 6.2e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM81881.1 - 5.9e-13 49.1 0.0 8.8e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EIM81881.1 - 1.7e-08 35.1 0.3 4.4e-08 33.7 0.3 1.8 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EIM81881.1 - 4.8e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RQC PF09382.10 EIM81881.1 - 0.0013 18.5 0.4 0.013 15.2 0.2 2.6 2 1 0 2 2 2 1 RQC domain AAA_22 PF13401.6 EIM81881.1 - 0.058 13.7 0.0 0.64 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.23 EIM81881.1 - 0.059 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain HEM4 PF02602.15 EIM81881.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DTHCT PF08070.11 EIM81881.1 - 0.36 11.6 8.0 0.87 10.3 8.0 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region F-box-like PF12937.7 EIM81882.1 - 4.2e-05 23.3 1.6 8.7e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like CPSF_A PF03178.15 EIM81883.1 - 6.2e-79 265.6 0.0 1.3e-78 264.5 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EIM81883.1 - 2.1e-20 72.8 0.0 3.4e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Hfx_Cass5 PF18287.1 EIM81884.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 GMC_oxred_N PF00732.19 EIM81885.1 - 5.9e-58 196.6 0.0 7.5e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM81885.1 - 1.4e-33 116.4 0.0 2.2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EIM81885.1 - 0.00032 20.0 0.1 0.00071 18.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM81885.1 - 0.0005 20.3 1.9 0.00067 19.8 0.5 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM81885.1 - 0.0025 17.0 1.9 0.021 13.9 1.4 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EIM81885.1 - 0.003 16.7 0.6 0.0045 16.1 0.6 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EIM81885.1 - 0.0075 15.6 0.0 0.024 13.9 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM81885.1 - 0.038 13.3 0.3 0.81 9.0 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 EIM81885.1 - 0.053 13.1 0.8 0.1 12.2 0.8 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EIM81885.1 - 0.083 12.1 0.4 0.23 10.7 0.2 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EIM81885.1 - 0.43 9.2 2.0 0.49 9.0 1.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EIM81885.1 - 0.47 11.0 2.0 6 7.5 1.4 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RPE65 PF03055.15 EIM81886.1 - 2e-111 373.5 0.0 2.2e-111 373.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF1181 PF06680.11 EIM81886.1 - 0.12 12.2 0.2 0.38 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1181) MFS_1 PF07690.16 EIM81887.1 - 4.3e-40 137.7 45.9 4.3e-40 137.7 45.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81887.1 - 0.00024 20.1 30.2 0.00032 19.7 11.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter ELFV_dehydrog PF00208.21 EIM81888.1 - 2.8e-76 256.5 0.8 3.5e-76 256.1 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EIM81888.1 - 1.8e-50 170.2 0.0 4.7e-50 168.8 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pyr_redox_2 PF07992.14 EIM81888.1 - 0.024 13.9 0.2 0.49 9.6 0.2 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EIM81888.1 - 0.17 12.3 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding IF4E PF01652.18 EIM81890.1 - 1.8e-54 183.9 0.0 2.5e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 EIM81890.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) 3Beta_HSD PF01073.19 EIM81891.1 - 8.4e-12 44.7 0.0 3.9e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM81891.1 - 1.1e-11 44.7 0.0 2.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM81891.1 - 3.1e-07 30.5 0.0 5.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIM81891.1 - 1.1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIM81891.1 - 0.00011 21.4 0.0 0.0006 19.0 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EIM81891.1 - 0.00035 19.8 0.0 0.043 13.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 EIM81891.1 - 0.00053 19.5 0.5 0.0014 18.1 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EIM81891.1 - 0.005 16.4 0.1 0.0097 15.5 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EIM81891.1 - 0.089 11.9 0.1 0.3 10.1 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain DUF1761 PF08570.10 EIM81893.1 - 0.059 13.6 4.3 0.32 11.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) Zn_clus PF00172.18 EIM81894.1 - 3.1e-09 36.8 9.0 4.6e-09 36.2 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3Beta_HSD PF01073.19 EIM81898.1 - 1.4e-11 43.9 0.0 2.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM81898.1 - 1.8e-10 40.7 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM81898.1 - 7e-07 29.3 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM81898.1 - 1.6e-06 27.5 0.0 7.5e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIM81898.1 - 2.8e-05 23.7 0.0 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EIM81898.1 - 4.5e-05 23.1 0.1 0.00017 21.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EIM81898.1 - 0.0038 16.7 0.6 0.018 14.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EIM81898.1 - 0.042 13.8 0.6 1.4 8.8 0.6 2.4 1 1 0 1 1 1 0 KR domain GST_N_3 PF13417.6 EIM81899.1 - 1.2e-09 38.5 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM81899.1 - 1e-06 29.0 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM81899.1 - 7.7e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM81899.1 - 2.4e-05 24.3 0.1 4.6e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EIM81899.1 - 0.082 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_C PF00043.25 EIM81899.1 - 0.12 12.6 0.1 0.35 11.1 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.7 EIM81900.1 - 2.6e-08 34.7 0.0 3.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.7 EIM81901.1 - 3.1e-05 23.8 0.0 7.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF2236 PF09995.9 EIM81903.1 - 7.1e-28 98.4 0.0 1.2e-27 97.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Sin3a_C PF16879.5 EIM81904.1 - 5.7e-66 223.1 3.1 4.4e-64 216.9 0.0 3.4 3 1 0 3 3 3 2 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EIM81904.1 - 1.8e-37 127.3 0.6 8.9e-37 125.1 0.1 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 EIM81904.1 - 1.2e-34 118.2 1.1 1.7e-17 63.3 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat DUF3915 PF13054.6 EIM81904.1 - 0.44 10.5 1.4 1.3 9.0 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3294 PF07957.11 EIM81906.1 - 0.00032 20.5 0.0 0.0028 17.4 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3294) MFS_1 PF07690.16 EIM81907.1 - 8.2e-29 100.6 40.1 8.2e-29 100.6 40.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM81907.1 - 0.0003 19.8 10.0 0.0003 19.8 10.0 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter TraL PF07178.11 EIM81907.1 - 0.0091 16.4 0.9 0.0091 16.4 0.9 3.0 2 1 1 3 3 3 1 TraL protein MFS_4 PF06779.14 EIM81907.1 - 0.044 13.1 27.4 0.071 12.4 27.4 1.2 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB CheR_N PF03705.15 EIM81908.1 - 0.13 12.0 1.2 0.17 11.6 1.2 1.2 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain ADH_zinc_N PF00107.26 EIM81909.1 - 3.2e-16 59.5 0.0 6.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM81909.1 - 2e-07 30.8 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM81909.1 - 2e-05 25.7 0.0 3.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM81909.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase HLH PF00010.26 EIM81911.1 - 8e-19 67.3 0.0 3.7e-18 65.2 0.0 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain PAP2 PF01569.21 EIM81915.1 - 8.3e-18 64.5 4.3 8.3e-18 64.5 4.3 3.3 3 1 1 4 4 4 1 PAP2 superfamily DUF2254 PF10011.9 EIM81915.1 - 0.019 13.8 0.2 0.041 12.7 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) p450 PF00067.22 EIM81916.1 - 3.6e-55 187.6 0.0 2.9e-52 178.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 S1-P1_nuclease PF02265.16 EIM81917.1 - 2.8e-43 148.6 0.1 7.2e-39 134.1 0.0 2.6 2 1 0 2 2 2 2 S1/P1 Nuclease AA_permease_2 PF13520.6 EIM81918.1 - 5.1e-47 160.7 48.5 6.5e-47 160.3 48.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM81918.1 - 2.2e-28 99.1 41.7 3e-28 98.7 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.6 EIM81918.1 - 0.0037 15.8 2.7 0.0037 15.8 2.7 2.0 3 0 0 3 3 3 1 dsRNA-gated channel SID-1 MS_channel PF00924.18 EIM81918.1 - 0.12 11.9 1.3 0.31 10.6 1.3 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel bZIP_1 PF00170.21 EIM81919.1 - 5.6e-07 29.6 6.7 1.9e-06 27.9 6.7 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EIM81919.1 - 0.00021 21.3 3.2 0.00021 21.3 3.2 2.8 2 1 1 3 3 3 2 Basic region leucine zipper TMF_DNA_bd PF12329.8 EIM81919.1 - 4.5 7.3 6.7 0.23 11.5 0.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding F-box-like PF12937.7 EIM81920.1 - 0.0032 17.3 0.1 0.0092 15.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like AAA_12 PF13087.6 EIM81921.1 - 6e-43 146.8 0.0 9.2e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM81921.1 - 5.7e-28 98.4 0.0 1.6e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EIM81921.1 - 4.6e-13 49.3 0.0 2.3e-12 47.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EIM81921.1 - 1.5e-11 44.8 0.0 9.6e-11 42.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EIM81921.1 - 0.00014 21.7 1.1 11 5.6 0.0 4.2 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EIM81921.1 - 0.00019 20.9 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 EIM81921.1 - 0.00045 19.8 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain zf-C2H2_jaz PF12171.8 EIM81921.1 - 0.0012 19.1 5.0 0.0082 16.4 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM81921.1 - 0.0014 18.9 10.1 0.032 14.6 0.1 4.3 3 1 0 3 3 3 1 Zinc-finger of C2H2 type AAA_22 PF13401.6 EIM81921.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-C3H1 PF10650.9 EIM81921.1 - 0.021 14.6 1.0 0.045 13.5 1.0 1.5 1 0 0 1 1 1 0 Putative zinc-finger domain Mg_chelatase PF01078.21 EIM81921.1 - 0.029 13.8 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 EIM81921.1 - 0.037 13.8 0.8 0.14 12.0 0.4 2.2 2 1 0 2 2 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 EIM81921.1 - 0.041 13.9 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 EIM81921.1 - 0.043 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIM81921.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region OrsD PF12013.8 EIM81921.1 - 1.9 9.0 9.6 4 7.9 0.2 3.2 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA PF00004.29 EIM81922.1 - 5.5e-44 149.8 0.0 9.7e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EIM81922.1 - 1e-08 35.5 0.0 2.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EIM81922.1 - 2.8e-08 33.6 0.8 7e-08 32.3 0.8 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EIM81922.1 - 4.3e-07 29.6 0.0 2.3e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EIM81922.1 - 2.3e-06 27.7 0.0 8.7e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIM81922.1 - 4.3e-06 27.2 0.0 7.6e-05 23.2 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM81922.1 - 5.6e-05 23.4 1.3 0.0055 17.0 0.2 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EIM81922.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EIM81922.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EIM81922.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM81922.1 - 0.0022 18.6 0.0 0.017 15.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EIM81922.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 EIM81922.1 - 0.0085 15.6 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 EIM81922.1 - 0.0092 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EIM81922.1 - 0.0095 15.3 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EIM81922.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EIM81922.1 - 0.02 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 EIM81922.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EIM81922.1 - 0.022 14.5 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EIM81922.1 - 0.027 14.2 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 EIM81922.1 - 0.033 13.3 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EIM81922.1 - 0.039 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EIM81922.1 - 0.044 13.8 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIM81922.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 EIM81922.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EIM81922.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIM81922.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EIM81922.1 - 0.12 12.3 0.0 0.69 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_19 PF13245.6 EIM81922.1 - 0.14 12.4 0.0 0.69 10.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 EIM81922.1 - 0.16 11.7 0.2 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 EIM81922.1 - 0.17 12.2 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein CorA PF01544.18 EIM81924.1 - 1.7e-10 40.7 1.7 2.5e-10 40.2 1.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ER_lumen_recept PF00810.18 EIM81926.1 - 6.2e-25 88.8 12.3 8.5e-25 88.3 12.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor TatC PF00902.18 EIM81926.1 - 0.012 15.5 11.1 0.017 15.0 10.8 1.5 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) GPI2 PF06432.11 EIM81926.1 - 0.83 9.0 10.4 1 8.8 8.7 1.8 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase TctB PF07331.11 EIM81926.1 - 4.8 7.5 12.1 3.3 8.0 9.2 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family UNC-50 PF05216.13 EIM81930.1 - 5e-84 281.3 16.2 5.6e-84 281.1 16.2 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1435 PF07256.12 EIM81930.1 - 0.01 15.9 1.0 0.025 14.6 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) AA_permease_2 PF13520.6 EIM81932.1 - 9e-45 153.3 46.5 1.1e-44 152.9 46.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM81932.1 - 1.4e-18 66.8 39.8 2e-18 66.2 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease MS_channel PF00924.18 EIM81932.1 - 0.018 14.6 0.7 0.049 13.2 0.7 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel SID-1_RNA_chan PF13965.6 EIM81932.1 - 0.44 8.9 3.1 0.69 8.2 3.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neurensin PF14927.6 EIM81932.1 - 0.53 10.0 2.9 1.2 8.9 0.3 2.7 3 0 0 3 3 3 0 Neurensin AA_permease_2 PF13520.6 EIM81933.1 - 3.8e-44 151.2 39.7 4.8e-44 150.9 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM81933.1 - 2.6e-25 89.0 34.5 3.6e-25 88.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease MS_channel PF00924.18 EIM81933.1 - 0.0061 16.1 1.4 0.015 14.8 1.4 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3043 PF11241.8 EIM81933.1 - 0.014 15.4 1.6 0.97 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) AA_permease_2 PF13520.6 EIM81934.1 - 1.9e-48 165.3 47.2 2.5e-48 165.0 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM81934.1 - 1.9e-28 99.3 38.3 2.6e-28 98.9 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease Methyltransf_16 PF10294.9 EIM81935.1 - 0.0012 18.6 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EIM81935.1 - 0.0067 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Metallophos PF00149.28 EIM81936.1 - 6.3e-37 128.1 0.0 9.5e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1828 PF08861.10 EIM81937.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF1828 Abhydrolase_3 PF07859.13 EIM81938.1 - 1.4e-10 41.4 0.1 7.5e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EIM81938.1 - 1.7e-05 23.9 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EIM81938.1 - 3.9e-05 23.2 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EIM81938.1 - 0.00016 21.1 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 EIM81938.1 - 0.0003 19.8 0.0 0.002 17.1 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase PF07224.11 EIM81938.1 - 0.00032 19.8 0.1 0.00045 19.3 0.1 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 EIM81938.1 - 0.14 11.9 0.0 9.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase 3HBOH PF10605.9 EIM81938.1 - 0.14 10.3 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Abhydrolase_3 PF07859.13 EIM81939.1 - 3.5e-10 40.1 0.0 6.5e-10 39.2 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM81939.1 - 3.7e-06 26.4 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EIM81939.1 - 3.3e-05 23.5 0.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EIM81939.1 - 0.00045 19.2 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EIM81939.1 - 0.021 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase COesterase PF00135.28 EIM81939.1 - 0.13 11.1 0.0 0.52 9.1 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family CFIA_Pcf11 PF11526.8 EIM81940.1 - 0.48 11.0 5.5 0.89 10.1 5.5 1.4 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Cupredoxin_1 PF13473.6 EIM81942.1 - 2.5e-06 27.6 0.6 0.53 10.4 0.0 3.9 4 0 0 4 4 4 2 Cupredoxin-like domain DUF5067 PF16729.5 EIM81942.1 - 0.015 15.2 2.0 22 5.0 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5067) DUF442 PF04273.13 EIM81942.1 - 0.02 15.0 1.6 5.9 7.0 0.0 3.7 4 0 0 4 4 4 0 Putative phosphatase (DUF442) DUF236 PF03057.14 EIM81942.1 - 0.071 13.1 0.6 17 5.5 0.1 2.5 2 0 0 2 2 2 0 DUF236 repeat I-set PF07679.16 EIM81942.1 - 0.17 11.9 0.1 23 5.2 0.0 3.1 4 0 0 4 4 4 0 Immunoglobulin I-set domain TEX33 PF15400.6 EIM81942.1 - 0.18 12.3 0.0 19 5.7 0.0 2.4 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family MFAP1 PF06991.11 EIM81943.1 - 5.8 6.7 12.4 11 5.7 12.4 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Oxysterol_BP PF01237.18 EIM81944.1 - 5.9e-42 143.8 3.5 7.4e-23 81.0 2.4 3.3 2 1 0 2 2 2 2 Oxysterol-binding protein SRI PF08236.11 EIM81944.1 - 0.0073 16.5 1.0 0.014 15.5 1.0 1.4 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Abhydrolase_3 PF07859.13 EIM81945.1 - 6e-06 26.3 0.0 3.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM81945.1 - 0.00032 19.7 0.0 0.0009 18.2 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 EIM81945.1 - 0.0084 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme p450 PF00067.22 EIM81947.1 - 9.4e-57 192.8 0.0 2.1e-56 191.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Melibiase_2 PF16499.5 EIM81948.1 - 1.6e-64 217.8 9.7 8.8e-64 215.4 9.7 2.0 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EIM81948.1 - 2.2e-12 46.9 0.6 4.7e-12 45.8 0.6 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EIM81948.1 - 5.9e-08 32.0 0.1 1.2e-07 31.0 0.0 1.4 2 0 0 2 2 2 1 Melibiase P_proprotein PF01483.20 EIM81948.1 - 0.025 14.6 0.3 0.061 13.4 0.3 1.6 1 0 0 1 1 1 0 Proprotein convertase P-domain Creatinase_N_2 PF16189.5 EIM81949.1 - 1.2e-50 171.7 0.0 1.4e-49 168.2 0.0 2.6 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EIM81949.1 - 9.7e-47 159.4 0.0 1.4e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EIM81949.1 - 8.2e-27 93.1 1.2 4.4e-26 90.7 0.1 2.8 4 0 0 4 4 4 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EIM81949.1 - 2e-21 77.0 0.0 3.6e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Mg_trans_NIPA PF05653.14 EIM81950.1 - 4.7e-97 324.7 11.8 5.6e-97 324.4 11.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EIM81950.1 - 0.0042 17.3 3.6 0.0042 17.3 3.6 3.5 3 1 0 3 3 3 2 EamA-like transporter family DUF2157 PF09925.9 EIM81950.1 - 0.054 13.3 0.6 0.29 10.9 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Acyl_transf_3 PF01757.22 EIM81950.1 - 0.092 11.8 11.4 1.1 8.2 10.1 2.2 1 1 0 1 1 1 0 Acyltransferase family TFIIF_alpha PF05793.12 EIM81950.1 - 0.26 9.8 6.4 0.36 9.4 6.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 EIM81950.1 - 5.1 5.1 8.8 7.6 4.5 8.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EIM81950.1 - 6.8 5.9 6.9 9.9 5.4 6.9 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EIM81950.1 - 7.6 4.7 6.2 9.9 4.3 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase_Tyr PF07714.17 EIM81951.1 - 2.1e-50 171.5 0.0 2.7e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM81951.1 - 8.2e-38 130.3 0.0 1.1e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EIM81951.1 - 7.6e-05 21.7 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EIM81951.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIM81951.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EIM81951.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_12 PF13087.6 EIM81952.1 - 2.1e-36 125.4 0.0 3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM81952.1 - 2.6e-26 93.0 0.0 1.9e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EIM81952.1 - 2.4e-10 40.5 0.0 8.4e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM81952.1 - 2.1e-09 37.9 0.0 1.6e-08 35.0 0.0 2.4 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 EIM81952.1 - 4.1e-05 23.1 0.0 0.093 12.2 0.0 2.5 3 0 0 3 3 3 2 PhoH-like protein AAA_16 PF13191.6 EIM81952.1 - 0.00018 22.0 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 EIM81952.1 - 0.00031 20.8 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIM81952.1 - 0.0057 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 EIM81952.1 - 0.011 14.9 0.0 0.4 9.8 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase UvrD-helicase PF00580.21 EIM81952.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 EIM81952.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 EIM81952.1 - 0.038 14.4 0.0 0.091 13.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIM81952.1 - 0.039 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 EIM81952.1 - 0.04 13.8 0.0 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Helicase AAA_5 PF07728.14 EIM81952.1 - 0.051 13.6 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIM81952.1 - 0.053 13.3 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EIM81952.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.6 EIM81952.1 - 0.22 10.9 0.0 1.3 8.3 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain p450 PF00067.22 EIM81953.1 - 2.5e-69 234.2 0.0 3.1e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ER_lumen_recept PF00810.18 EIM81955.1 - 2.2e-19 70.8 4.9 2.2e-19 70.8 4.9 1.8 2 0 0 2 2 2 1 ER lumen protein retaining receptor YwiC PF14256.6 EIM81955.1 - 6 7.2 10.2 1.1 9.5 1.3 2.6 1 1 0 2 2 2 0 YwiC-like protein DER1 PF04511.15 EIM81956.1 - 4.1e-32 111.7 0.9 4.9e-32 111.4 0.9 1.0 1 0 0 1 1 1 1 Der1-like family Ycf4 PF02392.16 EIM81956.1 - 0.18 11.3 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 Ycf4 Pribosyltran PF00156.27 EIM81957.1 - 4e-14 52.4 0.0 5.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ion_trans_2 PF07885.16 EIM81958.1 - 1.1e-27 95.8 33.4 3.2e-15 55.9 12.5 2.8 3 0 0 3 3 3 2 Ion channel Aldo_ket_red PF00248.21 EIM81959.1 - 9.3e-40 136.6 0.0 1.4e-39 136.0 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family ChAPs PF09295.10 EIM81960.1 - 1e-146 489.0 0.0 3e-146 487.4 0.0 1.7 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EIM81960.1 - 7.9e-06 26.3 0.3 0.0027 18.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM81960.1 - 0.00069 19.5 6.8 5.5 7.4 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EIM81960.1 - 0.00072 18.8 1.7 0.39 9.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM81960.1 - 0.0037 17.4 0.1 1.6 9.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM81960.1 - 0.0099 16.1 0.9 1.1 9.5 0.8 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EIM81960.1 - 0.055 14.3 4.8 25 6.1 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 EIM81960.1 - 0.22 10.4 0.0 0.22 10.4 0.0 2.4 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 EIM81960.1 - 7.6 7.3 8.9 2 9.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2046 PF09755.9 EIM81961.1 - 1.2e-10 41.2 7.1 1.2e-10 41.2 7.1 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) RNase_H2-Ydr279 PF09468.10 EIM81961.1 - 0.17 12.1 2.0 0.3 11.2 2.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain MFS_1 PF07690.16 EIM81962.1 - 8.9e-20 70.9 25.7 4.6e-18 65.3 24.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1240 PF06836.12 EIM81962.1 - 0.13 12.8 0.8 17 6.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) MFS_1 PF07690.16 EIM81963.1 - 9.4e-27 93.8 33.7 9.5e-27 93.8 31.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 EIM81964.1 - 8.4e-53 179.4 0.0 1.5e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM81964.1 - 5.6e-48 163.9 0.0 9.6e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM81964.1 - 5.9e-26 90.4 0.1 1.2e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EIM81964.1 - 6.8e-13 48.7 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 EIM81964.1 - 0.061 13.7 0.0 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family AA_kinase PF00696.28 EIM81965.1 - 7.3e-36 124.0 0.0 6.2e-35 120.9 0.0 2.1 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EIM81965.1 - 4.4e-08 32.8 1.5 6.1e-05 22.7 0.1 2.7 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 EIM81965.1 - 5.6e-07 29.2 6.9 0.0047 16.7 0.2 3.2 3 0 0 3 3 3 2 ACT domain efb-c PF12199.8 EIM81965.1 - 0.091 12.8 0.1 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal Zn_clus PF00172.18 EIM81966.1 - 3.9e-07 30.1 12.0 5.6e-07 29.6 12.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 EIM81966.1 - 0.063 13.6 3.2 0.1 13.0 3.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) G-alpha PF00503.20 EIM81967.1 - 5.5e-124 413.9 0.0 2.3e-123 411.8 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM81967.1 - 1.1e-07 31.4 0.1 0.00051 19.5 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family TniB PF05621.11 EIM81967.1 - 0.0019 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein DUF3915 PF13054.6 EIM81967.1 - 0.011 15.7 7.5 0.025 14.6 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) AAA_29 PF13555.6 EIM81967.1 - 0.03 14.1 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 EIM81967.1 - 0.055 12.6 0.6 0.71 9.0 0.2 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF3100 PF11299.8 EIM81967.1 - 2.5 7.5 3.3 4.3 6.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) 2-Hacid_dh_C PF02826.19 EIM81968.1 - 5.7e-39 133.3 0.0 1.8e-37 128.5 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM81968.1 - 5.3e-25 87.6 0.0 6.3e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Glyco_hydro_61 PF03443.14 EIM81969.1 - 3.4e-54 183.9 0.0 4.1e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NACHT PF05729.12 EIM81970.1 - 2.8e-11 43.6 0.0 5.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 EIM81970.1 - 1.6e-06 27.8 0.5 1.6e-06 27.8 0.5 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 EIM81970.1 - 1.6e-05 25.4 0.1 9.1e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.6 EIM81970.1 - 0.0014 18.9 0.2 0.0039 17.5 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_22 PF13401.6 EIM81970.1 - 0.0087 16.3 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EIM81970.1 - 0.09 13.2 0.0 0.29 11.6 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_6 PF13174.6 EIM81970.1 - 0.15 12.8 1.0 8.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 EIM81972.1 - 5e-49 167.0 0.8 5.7e-46 157.0 0.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM81972.1 - 8.6e-47 159.1 3.2 1.6e-44 151.7 3.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM81972.1 - 1.1e-05 25.4 1.0 2.6e-05 24.2 1.0 1.6 1 1 0 1 1 1 1 KR domain zf-RING_2 PF13639.6 EIM81973.1 - 3.8e-07 30.3 7.7 7.2e-07 29.4 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EIM81973.1 - 2.3e-05 24.5 4.3 4.7e-05 23.5 4.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EIM81973.1 - 0.0018 18.3 2.0 0.0037 17.3 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EIM81973.1 - 0.0024 18.1 6.3 0.0057 16.9 6.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EIM81973.1 - 0.029 14.0 4.7 0.055 13.1 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EIM81973.1 - 0.04 14.2 6.9 0.077 13.3 6.9 1.5 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EIM81973.1 - 0.05 13.7 6.4 0.1 12.8 6.4 1.6 1 0 0 1 1 1 0 RING-variant domain BACK PF07707.15 EIM81973.1 - 0.05 13.7 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 BTB And C-terminal Kelch zf-C3HC4 PF00097.25 EIM81973.1 - 0.095 12.6 9.1 0.17 11.8 9.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM81973.1 - 0.1 12.5 7.8 0.22 11.4 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EIM81973.1 - 0.13 12.1 4.3 0.13 12.2 3.1 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 EIM81973.1 - 5.4 6.9 5.6 10 6.0 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain 2-Hacid_dh_C PF02826.19 EIM81974.1 - 5e-38 130.2 0.0 1.9e-36 125.1 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM81974.1 - 2.8e-26 91.8 0.0 3.3e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 EIM81974.1 - 0.17 12.5 0.0 0.4 11.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 EIM81975.1 - 1e-42 145.8 0.8 1.8e-42 145.0 0.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM81975.1 - 4.4e-34 118.0 1.3 1.7e-33 116.1 1.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM81975.1 - 7.7e-07 29.2 0.2 1.4e-06 28.3 0.2 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EIM81975.1 - 0.006 16.5 0.1 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EIM81975.1 - 0.016 14.6 0.1 0.039 13.4 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EIM81975.1 - 0.077 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase WD40 PF00400.32 EIM81976.1 - 4.9e-15 55.7 9.0 0.00023 21.9 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM81976.1 - 2.5e-07 30.9 1.1 0.0033 17.7 0.2 4.4 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 EIM81977.1 - 2.7e-34 118.5 0.0 2.5e-33 115.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM81977.1 - 2.2e-21 76.3 0.0 6e-20 71.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EIM81977.1 - 0.0025 17.1 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EIM81977.1 - 0.054 13.5 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CTP_synth_N PF06418.14 EIM81978.1 - 3.8e-121 403.4 0.5 4.9e-121 403.1 0.5 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EIM81978.1 - 1.3e-50 171.9 0.0 2e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIM81978.1 - 0.0038 17.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 EIM81978.1 - 0.039 14.0 0.0 0.049 13.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_hydro_1 PF00232.18 EIM81979.1 - 2e-149 497.9 3.1 2.3e-149 497.7 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_18 PF00704.28 EIM81980.1 - 1.1e-58 199.5 0.8 1.3e-58 199.2 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AAA_18 PF13238.6 EIM81981.1 - 1.8e-32 112.6 0.0 2.4e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EIM81981.1 - 1.3e-05 25.6 0.0 3.6e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EIM81981.1 - 7.2e-05 23.1 0.2 0.00025 21.3 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 EIM81981.1 - 8.6e-05 23.0 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EIM81981.1 - 0.00024 21.3 0.0 0.064 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM81981.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM81981.1 - 0.0012 19.3 0.4 0.0048 17.3 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 EIM81981.1 - 0.0017 18.3 0.6 0.89 9.4 0.2 2.3 1 1 1 2 2 2 2 Deoxynucleoside kinase KTI12 PF08433.10 EIM81981.1 - 0.0056 16.2 0.1 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ADK PF00406.22 EIM81981.1 - 0.01 15.9 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase CoaE PF01121.20 EIM81981.1 - 0.022 14.5 0.2 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase SKI PF01202.22 EIM81981.1 - 0.024 14.8 0.7 0.4 10.8 0.7 2.1 1 1 0 1 1 1 0 Shikimate kinase Thymidylate_kin PF02223.17 EIM81981.1 - 0.024 14.3 0.0 6.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 EIM81981.1 - 0.068 13.1 0.8 0.43 10.5 0.2 2.1 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 EIM81981.1 - 0.089 12.0 0.0 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EIM81981.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EIM81981.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EIM81981.1 - 0.092 12.5 0.0 0.22 11.2 0.0 1.6 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EIM81981.1 - 0.11 11.8 0.3 0.24 10.6 0.1 1.7 2 1 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EIM81981.1 - 0.11 13.0 0.1 0.19 12.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 EIM81981.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 EIM81981.1 - 0.14 11.1 0.7 0.32 9.9 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arnt_C PF18583.1 EIM81981.1 - 0.15 11.7 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Aminoarabinose transferase C-terminal domain RNA_helicase PF00910.22 EIM81981.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EIM81981.1 - 0.2 11.0 0.4 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 KaiC SRP19 PF01922.17 EIM81982.1 - 2.3e-26 92.5 0.0 3.8e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein CCDC24 PF15669.5 EIM81982.1 - 0.36 10.7 2.9 0.67 9.8 2.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Suf PF05843.14 EIM81982.1 - 0.78 9.7 2.9 1 9.3 2.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) JTB PF05439.12 EIM81983.1 - 0.0024 17.9 1.4 0.0025 17.8 0.0 1.6 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) Apt1 PF10351.9 EIM81983.1 - 0.076 11.9 1.2 0.077 11.8 1.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EIM81983.1 - 0.12 10.9 2.0 0.12 10.9 2.0 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 EIM81983.1 - 2.1 8.2 10.8 2.4 8.0 10.8 1.0 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EIM81984.1 - 1.7 7.1 9.8 2.8 6.4 9.8 1.3 1 0 0 1 1 1 0 Macoilin family Fe-S_biosyn PF01521.20 EIM81985.1 - 5.2e-09 36.3 0.0 6.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis APH PF01636.23 EIM81986.1 - 1.2e-10 41.8 0.3 1.5e-10 41.4 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM81986.1 - 3.1e-05 23.7 0.0 4.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EIM81986.1 - 0.038 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DLH PF01738.18 EIM81987.1 - 3e-07 30.2 0.0 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family DLH PF01738.18 EIM81993.1 - 2.4e-22 79.6 0.0 3e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family F-box-like PF12937.7 EIM81994.1 - 0.00046 20.0 0.2 0.0012 18.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81994.1 - 0.052 13.5 1.6 0.1 12.5 0.1 2.2 2 0 0 2 2 2 0 F-box domain zf-Sec23_Sec24 PF04810.15 EIM81995.1 - 0.014 15.4 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger F-box-like PF12937.7 EIM81996.1 - 2.5e-09 36.9 0.4 7.7e-09 35.3 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81996.1 - 0.00044 20.0 9.0 0.16 11.9 0.3 4.0 4 0 0 4 4 4 2 F-box domain LRR_1 PF00560.33 EIM81996.1 - 0.14 12.8 1.5 1.4e+02 3.6 0.1 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 EIM81996.1 - 0.23 11.9 4.8 16 6.1 0.1 4.2 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) SHMT PF00464.19 EIM81998.1 - 5.1e-170 565.4 0.0 5.8e-170 565.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EIM81998.1 - 0.0029 16.9 0.0 0.008 15.5 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase HrpB1_HrpK PF09613.10 EIM81998.1 - 0.023 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4142 PF13628.6 EIM81998.1 - 0.08 13.2 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) F-box-like PF12937.7 EIM81999.1 - 2.8e-11 43.1 2.2 1.7e-10 40.7 2.2 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM81999.1 - 0.003 17.4 10.0 0.48 10.4 0.2 4.7 4 1 0 4 4 4 2 F-box domain F-box-like PF12937.7 EIM82000.1 - 8.9e-11 41.5 0.5 3.3e-10 39.7 0.5 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82000.1 - 0.011 15.5 2.8 0.75 9.8 0.2 2.9 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 EIM82000.1 - 4.7 7.8 7.1 1.1e+02 3.4 0.0 4.7 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) COesterase PF00135.28 EIM82001.1 - 5.8e-57 193.7 0.0 2e-52 178.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family DUF1749 PF08538.10 EIM82001.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 EIM82001.1 - 0.048 13.5 0.1 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold NAD_binding_6 PF08030.12 EIM82002.1 - 8.7e-23 81.2 0.0 1.7e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EIM82002.1 - 1.4e-19 70.5 8.4 1.4e-19 70.5 8.4 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIM82002.1 - 2.4e-10 40.4 0.0 7.1e-09 35.7 0.0 2.8 2 1 0 2 2 2 1 FAD-binding domain Ntox22 PF15527.6 EIM82002.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial toxin 22 NAD_binding_1 PF00175.21 EIM82002.1 - 0.031 14.9 0.0 1.5 9.5 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain YqjK PF13997.6 EIM82002.1 - 0.045 14.0 0.4 0.35 11.2 0.0 2.6 4 0 0 4 4 4 0 YqjK-like protein DLH PF01738.18 EIM82003.1 - 2.8e-18 66.3 0.0 3.5e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S10 PF00450.22 EIM82004.1 - 2.6e-85 287.4 1.2 5e-84 283.1 1.2 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase FTR1 PF03239.14 EIM82005.1 - 1.1e-65 221.9 5.0 1.3e-65 221.6 5.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3180 PF11377.8 EIM82005.1 - 0.00053 20.1 0.2 0.00053 20.1 0.2 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3180) ETRAMP PF09716.10 EIM82005.1 - 0.48 10.5 1.6 20 5.3 0.0 2.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TMEM100 PF16311.5 EIM82005.1 - 2.5 7.7 6.3 1.7 8.3 3.5 2.0 2 0 0 2 2 2 0 Transmembrane protein 100 Wzy_C PF04932.15 EIM82005.1 - 4.1 7.0 14.5 0.26 10.9 2.3 2.7 2 1 0 2 2 2 0 O-Antigen ligase Cu-oxidase PF00394.22 EIM82006.1 - 3.1e-38 131.4 0.5 1.6e-34 119.3 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM82006.1 - 8.2e-35 119.5 3.1 3.9e-33 114.1 0.5 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM82006.1 - 1.4e-34 118.6 1.1 3.1e-32 111.1 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase Peptidase_S10 PF00450.22 EIM82008.1 - 7.3e-86 289.2 1.8 1.1e-85 288.7 1.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase GTP_CH_N PF12471.8 EIM82008.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Dioxygenase_C PF00775.21 EIM82009.1 - 1.1e-09 38.0 0.0 3.8e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Dioxygenase Cohesin PF00963.18 EIM82009.1 - 0.032 14.5 1.3 0.15 12.3 1.3 1.9 1 1 0 1 1 1 0 Cohesin domain SpaA PF17802.1 EIM82009.1 - 0.11 12.8 0.5 0.5 10.7 0.1 2.3 1 1 1 2 2 2 0 Prealbumin-like fold domain WD40 PF00400.32 EIM82010.1 - 3.3e-52 173.3 21.7 5.7e-12 46.0 1.3 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM82010.1 - 5.3e-19 68.3 2.4 0.00032 20.9 0.3 5.8 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM82010.1 - 4e-06 26.0 2.0 0.31 10.0 0.0 4.5 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 EIM82010.1 - 0.0012 18.8 2.2 0.13 12.2 0.2 2.3 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 EIM82010.1 - 0.023 14.6 0.1 4.1 7.5 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EIM82010.1 - 0.087 10.8 2.0 12 3.7 0.2 3.1 2 1 0 2 2 2 0 IKI3 family BCNT PF07572.12 EIM82011.1 - 1.5e-19 69.8 1.0 1.5e-19 69.8 1.0 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development Med3 PF11593.8 EIM82011.1 - 0.002 17.4 12.6 0.0028 16.9 12.6 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Putative_PNPOx PF01243.20 EIM82013.1 - 4.2e-06 26.9 0.0 7.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_1_2 PF00155.21 EIM82014.1 - 1.5e-53 182.3 0.0 1.9e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIM82014.1 - 0.056 12.0 0.0 0.12 10.9 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Ferric_reduct PF01794.19 EIM82015.1 - 2.7e-17 63.1 6.1 2.7e-17 63.1 6.1 2.7 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EIM82015.1 - 9.5e-16 58.3 0.0 2.7e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIM82015.1 - 3.3e-06 27.1 0.0 4.1e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 FAD-binding domain F-box-like PF12937.7 EIM82016.1 - 0.00036 20.3 0.1 0.00092 19.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82016.1 - 0.63 10.0 2.8 0.59 10.1 0.4 2.2 2 1 0 2 2 2 0 F-box domain Cellulase PF00150.18 EIM82017.1 - 7.3e-44 150.3 0.0 9.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PCNA_N PF00705.18 EIM82018.1 - 9.8e-50 167.5 2.2 1.6e-49 166.8 1.7 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EIM82018.1 - 2.6e-38 131.1 0.1 3.7e-19 69.1 0.0 3.0 3 1 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EIM82018.1 - 8e-07 28.4 0.2 1.2e-05 24.6 0.2 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EIM82018.1 - 0.00024 20.6 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Rad9 Nop14 PF04147.12 EIM82018.1 - 0.026 12.7 29.9 0.045 12.0 29.9 1.4 1 0 0 1 1 1 0 Nop14-like family Hus1 PF04005.12 EIM82018.1 - 0.067 12.3 9.0 1.8 7.6 0.0 3.9 3 1 1 4 4 4 0 Hus1-like protein BUD22 PF09073.10 EIM82018.1 - 0.16 11.3 38.2 0.23 10.7 38.2 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EIM82018.1 - 2.3 7.6 40.2 3.5 7.0 40.2 1.2 1 0 0 1 1 1 0 SDA1 Histone PF00125.24 EIM82018.1 - 4.7 7.6 0.0 4.7 7.6 0.0 3.3 2 1 1 3 3 3 0 Core histone H2A/H2B/H3/H4 TFIIF_alpha PF05793.12 EIM82018.1 - 8.3 4.9 44.6 16 3.9 44.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.16 EIM82019.1 - 3.1e-21 75.7 21.1 4.1e-21 75.3 21.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TFIIA PF03153.13 EIM82020.1 - 9.3e-05 22.6 15.8 0.00013 22.1 15.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 EIM82020.1 - 0.0096 15.8 4.9 0.013 15.4 4.9 1.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SAPS PF04499.15 EIM82020.1 - 0.054 12.3 5.8 0.064 12.0 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 EIM82020.1 - 0.26 9.7 22.6 0.35 9.3 22.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Vfa1 PF08432.10 EIM82020.1 - 0.27 11.6 7.8 0.45 10.8 7.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 EIM82020.1 - 0.39 10.1 28.7 0.54 9.6 28.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIM82020.1 - 0.58 8.3 34.7 0.038 12.2 29.8 1.4 2 0 0 2 2 2 0 Nop14-like family Nop53 PF07767.11 EIM82020.1 - 0.61 9.4 13.8 1.1 8.6 13.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SpoIIIAH PF12685.7 EIM82020.1 - 1 9.1 9.2 1.6 8.5 9.2 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein PPL5 PF18168.1 EIM82020.1 - 1.5 8.0 4.9 2.5 7.3 4.9 1.3 1 0 0 1 1 1 0 Prim-pol family 5 BUD22 PF09073.10 EIM82020.1 - 2.4 7.4 32.7 3.4 6.9 32.7 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 EIM82020.1 - 4.3 6.8 26.8 7.7 6.0 26.8 1.4 1 0 0 1 1 1 0 PPP4R2 eIF-3c_N PF05470.12 EIM82020.1 - 4.7 5.4 14.8 7.1 4.8 14.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Roughex PF06020.11 EIM82020.1 - 5.2 6.1 12.8 7.4 5.6 12.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 EIM82020.1 - 7.2 4.8 24.7 11 4.2 24.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Hira PF07569.11 EIM82022.1 - 2.6e-51 174.5 0.0 4.8e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EIM82022.1 - 2.4e-30 104.1 17.5 4.8e-07 30.4 0.4 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM82022.1 - 6.6e-13 48.8 1.1 0.28 11.5 0.0 6.3 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain DUF4336 PF14234.6 EIM82023.1 - 6.1e-13 48.6 0.0 7.1e-08 32.0 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) DsrD PF08679.11 EIM82023.1 - 0.088 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Ribosomal_L44 PF00935.19 EIM82024.1 - 1.1e-36 125.1 12.1 1.8e-36 124.5 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ank_5 PF13857.6 EIM82025.1 - 1.3e-07 31.8 0.0 8.7e-07 29.1 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM82025.1 - 1.5e-06 28.0 0.0 0.035 14.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EIM82025.1 - 3.7e-06 27.4 0.0 1.3e-05 25.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIM82025.1 - 7.8e-06 26.1 0.3 0.0095 16.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EIM82025.1 - 9.3e-05 22.9 0.0 0.0064 17.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 EIM82025.1 - 0.0052 17.0 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM82025.1 - 0.043 14.2 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_3 PF13606.6 EIM82026.1 - 4.1e-06 26.7 0.1 0.059 13.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EIM82026.1 - 4.9e-05 23.8 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIM82026.1 - 0.00053 20.3 1.2 0.054 14.0 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EIM82026.1 - 0.0015 18.8 0.1 0.055 13.8 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIM82026.1 - 0.016 15.7 0.1 0.1 13.2 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 EIM82026.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EIM82026.1 - 0.11 12.6 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 EIM82027.1 - 2.4e-05 24.7 0.0 6.4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM82027.1 - 0.0001 22.5 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_2 PF12796.7 EIM82027.1 - 0.0015 19.1 0.0 0.0042 17.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Acetyltransf_10 PF13673.7 EIM82027.1 - 0.003 17.5 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM82027.1 - 0.0059 16.7 0.0 0.037 14.2 0.0 2.3 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase Ank_5 PF13857.6 EIM82027.1 - 0.0099 16.2 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EIM82027.1 - 0.027 14.9 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 EIM82027.1 - 0.028 14.9 0.0 0.24 12.1 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 EIM82027.1 - 0.03 14.9 0.1 0.2 12.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Cnd1 PF12717.7 EIM82028.1 - 0.0028 17.7 1.0 0.5 10.4 0.0 4.7 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIM82028.1 - 0.044 14.0 0.6 27 5.4 0.0 5.5 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 EIM82028.1 - 0.19 12.3 0.5 26 5.4 0.0 4.5 3 0 0 3 3 3 0 HEAT-like repeat NARP1 PF12569.8 EIM82029.1 - 2.3e-155 518.4 3.8 1.3e-152 509.3 0.2 3.0 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EIM82029.1 - 4.6e-07 29.4 8.1 0.0085 16.1 0.0 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM82029.1 - 1e-06 29.3 10.9 5.1 7.8 0.0 8.1 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM82029.1 - 3.3e-06 26.9 4.4 0.0069 16.5 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM82029.1 - 5.7e-06 26.7 17.8 0.21 12.1 0.1 8.6 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM82029.1 - 3.8e-05 23.3 2.9 0.0063 16.3 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM82029.1 - 0.00024 20.7 1.4 0.0027 17.3 0.1 3.3 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 EIM82029.1 - 0.0004 21.0 23.1 30 5.8 0.0 10.8 9 2 5 14 14 14 0 Tetratricopeptide repeat TPR_9 PF13371.6 EIM82029.1 - 0.0019 18.3 4.6 10 6.3 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat PhoQ_Sensor PF08918.10 EIM82029.1 - 0.026 14.4 0.2 0.4 10.5 0.0 2.6 2 1 1 3 3 3 0 PhoQ Sensor TPR_17 PF13431.6 EIM82029.1 - 0.032 14.6 0.0 89 3.8 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM82029.1 - 0.059 13.6 0.8 6.2 7.1 0.0 4.0 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EIM82029.1 - 0.065 13.9 0.2 2e+02 3.0 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82029.1 - 0.28 11.5 11.1 1.2 9.5 0.1 5.8 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM82029.1 - 0.8 9.9 5.4 3.3 8.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Alb1 PF09135.11 EIM82030.1 - 0.22 12.4 0.2 0.39 11.6 0.2 1.3 1 0 0 1 1 1 0 Alb1 DUF719 PF05334.13 EIM82031.1 - 0.022 15.0 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) GATA PF00320.27 EIM82032.1 - 1.3e-05 24.7 1.8 1.3e-05 24.7 1.8 2.7 2 0 0 2 2 2 2 GATA zinc finger Peptidase_M1_N PF17900.1 EIM82035.1 - 0.16 12.2 0.0 0.36 11.0 0.0 1.6 1 1 1 2 2 2 0 Peptidase M1 N-terminal domain KH_1 PF00013.29 EIM82036.1 - 1.7e-07 31.0 0.3 8.5e-06 25.5 0.2 2.4 2 0 0 2 2 2 1 KH domain Trp_repressor PF01371.19 EIM82036.1 - 0.033 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein DUF2666 PF10869.8 EIM82036.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) K_channel_TID PF07941.11 EIM82036.1 - 1.7 9.1 14.8 0.1 13.0 8.6 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain 3Beta_HSD PF01073.19 EIM82037.1 - 6.6e-30 104.1 0.0 1.6e-26 92.9 0.0 2.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM82037.1 - 1.2e-13 50.8 0.0 5.1e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EIM82037.1 - 6.7e-13 48.7 0.0 3.2e-05 23.5 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM82037.1 - 1.9e-06 27.5 0.0 0.0014 18.1 0.0 2.9 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM82037.1 - 7.9e-06 25.9 0.0 7e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM82037.1 - 0.00026 21.0 0.0 0.0031 17.4 0.0 2.4 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 EIM82037.1 - 0.0013 18.0 0.0 0.21 10.7 0.1 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EIM82037.1 - 0.018 15.3 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EIM82037.1 - 0.032 13.3 0.0 0.24 10.4 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 EIM82037.1 - 0.037 13.6 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Pkinase PF00069.25 EIM82038.1 - 3e-67 226.8 0.0 3e-67 226.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82038.1 - 7.5e-30 104.1 0.0 7.5e-30 104.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM82038.1 - 0.00029 19.9 0.0 0.00029 19.9 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain WD40 PF00400.32 EIM82039.1 - 9.7e-12 45.2 6.6 0.00021 22.0 0.4 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF3927 PF13064.6 EIM82039.1 - 0.14 12.1 1.5 0.99 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) Ge1_WD40 PF16529.5 EIM82039.1 - 0.17 10.8 0.1 3.2 6.6 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_5 PF13857.6 EIM82040.1 - 0.0033 17.7 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EIM82040.1 - 0.028 14.9 0.5 0.16 12.5 0.1 2.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 EIM82040.1 - 0.033 14.7 0.0 0.21 12.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 EIM82040.1 - 0.058 14.0 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM82040.1 - 0.092 13.3 0.0 0.45 11.1 0.1 2.0 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) FAD_binding_3 PF01494.19 EIM82041.1 - 8e-78 262.1 0.0 1.1e-77 261.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM82041.1 - 3.6e-30 105.2 0.0 6.1e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EIM82041.1 - 8.2e-07 28.4 3.0 1.5e-06 27.6 2.8 1.5 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EIM82041.1 - 4.5e-06 25.6 1.1 6.6e-06 25.1 1.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EIM82041.1 - 2.3e-05 23.9 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM82041.1 - 2.7e-05 23.6 0.2 5.7e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM82041.1 - 3.5e-05 23.2 0.2 6e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EIM82041.1 - 4.2e-05 23.3 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM82041.1 - 9.2e-05 22.6 0.2 0.00022 21.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EIM82041.1 - 0.00017 20.8 0.4 0.00025 20.3 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EIM82041.1 - 0.00021 20.3 0.1 0.00031 19.7 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EIM82041.1 - 0.0014 17.7 1.2 0.0023 17.0 1.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EIM82041.1 - 0.0022 18.5 0.1 0.0046 17.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM82041.1 - 0.0029 16.9 0.7 0.0048 16.2 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM82041.1 - 0.0044 16.3 1.0 0.0079 15.5 1.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EIM82041.1 - 0.01 16.1 0.0 0.037 14.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 EIM82041.1 - 0.039 13.9 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EIM82041.1 - 0.07 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EIM82041.1 - 0.072 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EIM82041.1 - 0.085 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EIM82042.1 - 4.5e-24 85.1 0.4 2.5e-13 49.7 0.0 3.4 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EIM82042.1 - 1.6e-06 28.3 0.2 6.3e-06 26.3 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIM82042.1 - 1.9e-06 27.4 0.0 9.3e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EIM82042.1 - 1.7e-05 24.6 0.5 0.0028 17.3 0.3 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM82042.1 - 4e-05 23.0 0.0 7.1e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM82042.1 - 4.9e-05 22.9 0.2 8e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EIM82042.1 - 0.0003 20.0 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EIM82042.1 - 0.00098 18.3 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EIM82042.1 - 0.0011 17.8 0.2 0.0018 17.1 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EIM82042.1 - 0.0057 17.2 0.0 0.27 11.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM82042.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM82042.1 - 0.097 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NACHT PF05729.12 EIM82043.1 - 4.4e-11 43.0 0.0 8.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EIM82043.1 - 3.1e-07 30.9 0.0 9.4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM82043.1 - 0.019 15.3 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.6 EIM82044.1 - 7.7e-54 178.2 41.3 1.4e-07 31.1 0.1 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82044.1 - 1.6e-22 79.6 17.8 0.029 14.7 0.0 9.1 2 1 7 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 EIM82044.1 - 3.2e-14 51.8 4.9 2.1 8.7 0.2 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC5 PF12862.7 EIM82044.1 - 1.7e-13 50.5 12.8 0.35 11.0 0.0 8.3 1 1 6 8 8 8 4 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 EIM82044.1 - 2.3e-06 27.4 0.1 32 5.1 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat RHH_3 PF12651.7 EIM82044.1 - 2.6e-06 27.3 0.0 10 6.2 0.0 7.0 8 0 0 8 8 8 0 Ribbon-helix-helix domain Sec16_C PF12931.7 EIM82044.1 - 3e-06 27.1 0.0 0.65 9.6 0.0 4.1 2 2 2 4 4 4 1 Sec23-binding domain of Sec16 Phage-MuB_C PF09077.11 EIM82044.1 - 9.9e-06 25.3 1.4 6.8 6.6 0.0 5.5 4 1 2 6 6 6 1 Mu B transposition protein, C terminal TPR_7 PF13176.6 EIM82044.1 - 3.3e-05 23.6 11.8 20 5.5 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF4404 PF14357.6 EIM82044.1 - 5.6e-05 23.7 5.8 3.6 8.3 0.0 5.9 3 2 5 8 8 8 1 Domain of unknown function (DUF4404) DUF3856 PF12968.7 EIM82044.1 - 0.00017 21.7 4.7 0.3 11.1 0.1 5.0 3 3 2 5 5 5 3 Domain of Unknown Function (DUF3856) Desmo_N PF06771.11 EIM82044.1 - 0.0078 16.5 0.0 7.4 7.0 0.0 4.6 2 2 3 5 5 5 1 Viral Desmoplakin N-terminus S-methyl_trans PF02574.16 EIM82044.1 - 0.02 14.7 1.0 4.8 6.9 0.0 3.7 1 1 2 4 4 4 0 Homocysteine S-methyltransferase Synaptonemal_3 PF15191.6 EIM82044.1 - 0.028 14.2 0.2 21 4.9 0.0 4.2 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 RPN7 PF10602.9 EIM82044.1 - 0.042 13.6 0.2 2.8 7.6 0.0 3.5 3 2 2 5 5 5 0 26S proteasome subunit RPN7 Rootletin PF15035.6 EIM82044.1 - 0.14 12.1 6.9 2.2 8.2 0.2 3.1 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SPOR PF05036.13 EIM82044.1 - 0.28 11.6 7.9 9.4 6.7 0.3 4.4 5 1 0 5 5 4 0 Sporulation related domain Lipoprotein_20 PF13942.6 EIM82044.1 - 0.66 9.9 7.2 11 5.9 0.2 4.5 4 1 1 5 5 5 0 YfhG lipoprotein TPR_6 PF13174.6 EIM82044.1 - 0.89 10.3 6.9 5.9 7.8 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat KIP1 PF07765.12 EIM82044.1 - 1.5 9.0 4.0 44 4.3 0.0 5.0 7 0 0 7 7 7 0 KIP1-like protein TPR_20 PF14561.6 EIM82044.1 - 1.7 9.1 18.4 11 6.4 0.3 7.1 3 2 6 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 EIM82044.1 - 2.1 8.9 14.3 22 5.7 0.1 7.4 10 0 0 10 10 9 0 Tetratricopeptide repeat Ribosomal_S26e PF01283.19 EIM82046.1 - 1.9e-50 169.8 7.7 2.2e-50 169.6 7.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Ysc84 PF04366.12 EIM82047.1 - 1e-39 135.2 0.7 1.7e-39 134.5 0.7 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EIM82047.1 - 2.3e-15 55.9 0.1 5.1e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EIM82047.1 - 1.4e-12 47.1 0.0 5.3e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EIM82047.1 - 4.5e-12 45.6 0.0 1.4e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain zf-PARP PF00645.18 EIM82048.1 - 1e-25 90.4 0.1 1.5e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CDC27 PF09507.10 EIM82048.1 - 0.0069 15.8 9.0 0.0092 15.4 9.0 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 TFIIF_alpha PF05793.12 EIM82048.1 - 4.4 5.8 15.0 5.9 5.4 15.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.16 EIM82049.1 - 1.9e-27 96.1 20.1 2.3e-27 95.8 20.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.19 EIM82050.1 - 1.5e-54 184.2 0.1 4.2e-54 182.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EIM82050.1 - 1.1e-49 167.9 0.0 2.1e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 EIM82050.1 - 1.5e-27 96.4 0.0 4.2e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EIM82050.1 - 3.5e-25 88.2 0.0 1.5e-24 86.2 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EIM82050.1 - 3.2e-19 68.8 0.0 6.6e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EIM82050.1 - 3.5e-06 27.2 0.0 0.00015 21.9 0.0 2.8 2 1 0 3 3 3 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 EIM82051.1 - 5.2e-38 130.9 0.1 9.3e-38 130.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EIM82051.1 - 5.4e-21 74.7 0.0 1.2e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 EIM82051.1 - 9.3e-20 70.5 0.0 7.1e-19 67.7 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 EIM82051.1 - 4.7e-13 49.3 5.5 3.2e-11 43.4 3.6 2.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 EIM82051.1 - 4.8e-13 49.5 0.9 4e-11 43.3 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EIM82051.1 - 1.5e-10 40.8 0.2 5.4e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EIM82051.1 - 3.2e-10 39.7 0.0 6.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EIM82051.1 - 0.00015 21.6 0.2 0.36 10.8 0.1 2.8 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 EIM82051.1 - 0.014 14.7 0.0 0.044 13.0 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase STI1 PF17830.1 EIM82051.1 - 0.083 12.8 0.1 3.8 7.5 0.1 2.8 3 0 0 3 3 3 0 STI1 domain NAD_binding_9 PF13454.6 EIM82051.1 - 0.1 12.6 1.5 13 5.7 0.0 3.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 EIM82052.1 - 1.2e-33 117.1 0.1 1.6e-33 116.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM82052.1 - 0.0004 19.7 0.0 0.0051 16.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM82052.1 - 0.0025 17.0 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glu_dehyd_C PF16912.5 EIM82052.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_8 PF13450.6 EIM82052.1 - 0.018 15.3 0.3 0.071 13.3 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM82052.1 - 0.025 13.8 0.1 0.045 13.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 EIM82052.1 - 0.027 14.9 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EIM82052.1 - 0.078 13.5 1.0 0.14 12.7 1.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EIM82052.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EIM82052.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EIM82052.1 - 0.25 10.0 4.1 0.94 8.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NUDIX PF00293.28 EIM82053.1 - 1.7e-09 37.8 0.4 3.8e-09 36.7 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain zf-C2H2_jaz PF12171.8 EIM82054.1 - 9.1e-12 44.9 19.9 0.016 15.5 0.0 7.4 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM82054.1 - 1.2e-11 44.6 28.5 0.031 14.7 0.0 8.6 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EIM82054.1 - 4.4e-10 39.5 43.2 0.012 16.4 0.1 9.3 9 0 0 9 9 8 6 C2H2-type zinc finger zf-RING_5 PF14634.6 EIM82054.1 - 7.8e-06 25.8 13.1 7.8e-06 25.8 13.1 5.0 5 2 1 6 6 5 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM82054.1 - 2.9e-05 23.9 12.5 2.9e-05 23.9 12.5 4.3 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.6 EIM82054.1 - 0.00015 21.7 28.1 0.0023 17.9 0.1 7.1 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EIM82054.1 - 0.00016 21.9 50.7 0.0098 16.3 0.1 8.9 10 1 1 11 11 7 2 Zinc finger, C2H2 type zf-C3HC4_3 PF13920.6 EIM82054.1 - 0.0002 21.1 11.4 0.0002 21.1 11.4 5.1 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM82054.1 - 0.00076 19.8 14.0 0.00076 19.8 14.0 4.8 4 1 0 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM82054.1 - 0.0013 18.5 13.3 0.0013 18.5 13.3 4.6 6 1 0 6 6 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_11 PF16622.5 EIM82054.1 - 0.014 15.2 9.3 1.6 8.6 0.0 5.3 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-RING_UBOX PF13445.6 EIM82054.1 - 0.034 14.2 16.0 0.024 14.6 9.2 3.4 2 2 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM82054.1 - 0.14 12.3 12.8 0.72 10.1 12.8 2.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2HC_2 PF13913.6 EIM82054.1 - 0.25 11.3 10.4 3.2 7.8 2.5 4.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 EIM82054.1 - 1.1 9.6 36.2 0.16 12.4 2.9 5.5 2 1 2 5 5 4 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.14 EIM82054.1 - 1.2 9.2 7.6 1 9.4 0.0 3.6 4 0 0 4 4 3 0 MYM-type Zinc finger with FCS sequence motif zf_ZIC PF18366.1 EIM82054.1 - 3.5 7.8 18.6 0.16 12.1 0.3 5.0 4 2 2 6 6 6 0 Zic proteins zinc finger domain HNH_5 PF14279.6 EIM82054.1 - 9.4 6.2 17.0 16 5.4 0.1 6.1 4 1 2 6 6 6 0 HNH endonuclease HLH PF00010.26 EIM82055.1 - 5.2e-10 39.1 0.2 1.5e-09 37.7 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sigma_1s PF02454.16 EIM82055.1 - 0.087 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma 1s protein Sigma70_ner PF04546.13 EIM82055.1 - 0.24 11.3 4.9 0.071 13.0 1.4 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 EIM82055.1 - 2.6 6.2 5.7 4.4 5.5 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein HMG-CoA_red PF00368.18 EIM82056.1 - 7.9e-145 482.5 4.4 1.1e-144 482.0 4.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EIM82056.1 - 7.3e-16 58.4 2.0 1.9e-15 57.0 2.0 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EIM82056.1 - 3.4e-06 25.5 1.0 5.4e-06 24.8 1.0 1.2 1 0 0 1 1 1 1 Patched family HPIH PF13323.6 EIM82056.1 - 0.11 12.4 1.8 0.25 11.2 1.8 1.6 1 0 0 1 1 1 0 N-terminal domain with HPIH motif U1snRNP70_N PF12220.8 EIM82056.1 - 0.36 11.5 1.1 1.2 9.8 1.1 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal His_Phos_2 PF00328.22 EIM82057.1 - 1.7e-18 67.1 0.0 2.6e-16 60.0 0.0 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mannosyl_trans3 PF11051.8 EIM82059.1 - 1.3e-22 80.5 0.0 3.7e-14 52.7 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative F-box-like PF12937.7 EIM82060.1 - 2.1e-09 37.2 0.6 6.8e-09 35.5 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82060.1 - 0.0039 17.0 0.1 0.013 15.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain NAD_binding_4 PF07993.12 EIM82061.1 - 3.5e-69 232.8 0.0 6.4e-69 232.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM82061.1 - 2.4e-67 227.4 0.0 3.3e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EIM82061.1 - 6e-13 48.3 0.0 3.2e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EIM82061.1 - 1.6e-12 47.6 0.0 5.1e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EIM82061.1 - 4.8e-10 39.3 0.0 8.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM82061.1 - 4.1e-09 35.8 0.0 7.4e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EIM82061.1 - 5.2e-05 24.1 0.0 0.00018 22.4 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EIM82061.1 - 0.00051 19.5 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F-box-like_2 PF13013.6 EIM82062.1 - 0.0069 16.3 0.1 0.023 14.7 0.1 1.8 1 1 0 1 1 1 1 F-box-like domain F-box-like PF12937.7 EIM82062.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 F-box-like Pox_Rap94 PF03294.14 EIM82062.1 - 0.21 9.6 0.0 0.3 9.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 Ribonuclease_T2 PF00445.18 EIM82063.1 - 8.4e-37 127.2 0.2 1.2e-36 126.7 0.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family ADH_N PF08240.12 EIM82067.1 - 2.9e-32 110.8 2.9 5e-32 110.0 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM82067.1 - 6.8e-16 58.4 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM82067.1 - 4.1e-11 42.8 0.0 6.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIM82067.1 - 1.2e-06 29.6 0.0 2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EIM82067.1 - 0.0024 17.2 1.0 0.0037 16.5 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 EIM82067.1 - 0.019 15.2 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Staph_opine_DH PF10100.9 EIM82067.1 - 0.02 13.5 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Metallophos PF00149.28 EIM82068.1 - 2.1e-13 51.2 0.8 3.1e-13 50.7 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM82068.1 - 5e-08 33.3 0.9 1.1e-06 29.0 0.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 EIM82069.1 - 0.062 13.2 1.1 0.5 10.3 0.1 2.6 2 0 0 2 2 2 0 F-box-like DUF664 PF04978.12 EIM82070.1 - 0.16 12.4 0.4 1 9.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF664) p450 PF00067.22 EIM82072.1 - 1e-45 156.4 0.0 6.7e-28 97.6 0.0 2.8 2 2 0 2 2 2 2 Cytochrome P450 MBOAT_2 PF13813.6 EIM82073.1 - 3.6e-14 52.8 2.7 8.8e-14 51.5 2.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TrkA_TMD PF18613.1 EIM82073.1 - 6.7 6.2 15.1 0.12 11.9 2.6 2.9 3 0 0 3 3 3 0 Tyrosine kinase receptor A trans-membrane domain La PF05383.17 EIM82074.1 - 3.3e-14 52.7 0.0 5.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 La domain DUF3915 PF13054.6 EIM82074.1 - 3 7.9 7.8 9.7 6.2 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Lactamase_B_2 PF12706.7 EIM82076.1 - 4.9e-14 52.3 0.1 9.7e-08 31.8 0.2 3.0 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EIM82076.1 - 2.9e-11 42.9 0.2 1.1e-10 41.0 0.2 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 EIM82076.1 - 0.022 14.8 0.2 0.4 10.7 0.0 3.1 4 0 0 4 4 4 0 Metallo-beta-lactamase superfamily G-alpha PF00503.20 EIM82077.1 - 2.2e-101 339.5 0.0 2.6e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM82077.1 - 2.1e-10 40.3 0.1 4.3e-06 26.3 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EIM82077.1 - 0.0047 17.1 0.0 0.54 10.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EIM82077.1 - 0.048 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EIM82077.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EIM82077.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pmp3 PF01679.17 EIM82078.1 - 1.2e-23 83.1 11.0 1.4e-23 82.8 11.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator HEV_ORF1 PF02444.16 EIM82079.1 - 0.00056 20.4 0.2 0.00056 20.4 0.2 2.2 2 0 0 2 2 2 1 Hepatitis E virus ORF-2 (Putative capsid protein) AdoHcyase PF05221.17 EIM82080.1 - 1.5e-133 444.5 0.0 4.7e-74 249.2 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EIM82080.1 - 3.7e-83 277.5 1.0 5.7e-83 276.8 1.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EIM82080.1 - 4.8e-09 35.8 0.1 9.1e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EIM82080.1 - 8e-05 22.3 0.2 0.00013 21.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EIM82080.1 - 0.003 17.8 0.0 0.0088 16.3 0.0 1.9 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 EIM82080.1 - 0.089 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.17 EIM82080.1 - 0.12 13.0 0.1 0.28 11.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UPF0180 PF03698.13 EIM82080.1 - 0.15 12.2 0.1 0.89 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) NAD_binding_7 PF13241.6 EIM82080.1 - 0.16 12.5 0.2 0.38 11.2 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Mitochondr_Som1 PF11093.8 EIM82081.1 - 5.1e-10 39.2 0.1 6.9e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DivIC PF04977.15 EIM82082.1 - 0.017 14.8 0.6 0.13 12.0 0.8 1.9 2 0 0 2 2 2 0 Septum formation initiator WAPL PF07814.13 EIM82083.1 - 1.2e-20 73.6 0.4 6.2e-17 61.4 0.0 3.2 1 1 1 2 2 2 2 Wings apart-like protein regulation of heterochromatin CDC45 PF02724.14 EIM82083.1 - 0.08 11.2 1.7 0.15 10.3 1.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Fes1 PF08609.10 EIM82083.1 - 4.3 8.3 8.2 3.6 8.5 0.1 2.9 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 BIR PF00653.21 EIM82084.1 - 4.3e-36 123.4 0.6 1.2e-18 67.5 0.6 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 EIM82084.1 - 2.3e-05 24.4 0.1 0.013 15.6 0.0 2.5 2 1 0 2 2 2 2 C3HC zinc finger-like zf-BED PF02892.15 EIM82084.1 - 0.0025 17.8 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 BED zinc finger Kelch_4 PF13418.6 EIM82085.1 - 0.031 14.3 0.3 5.7 7.0 0.1 3.5 2 1 1 3 3 3 0 Galactose oxidase, central domain RAP1 PF07218.11 EIM82085.1 - 1.3 7.2 15.0 1.8 6.8 15.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.12 EIM82085.1 - 2.7 8.4 7.9 5 7.5 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) p450 PF00067.22 EIM82087.1 - 8.5e-56 189.6 0.1 1.1e-55 189.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_7 PF14246.6 EIM82087.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain MutS_V PF00488.21 EIM82088.1 - 7.3e-82 274.0 0.2 1.2e-81 273.2 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIM82088.1 - 1.2e-35 123.5 2.8 1.2e-35 123.5 2.8 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EIM82088.1 - 5.6e-17 62.3 0.3 1.2e-14 54.8 0.0 3.5 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 EIM82088.1 - 3.9e-16 59.2 0.7 1.1e-15 57.8 0.7 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 EIM82088.1 - 7.3e-08 32.7 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain I IFT20 PF14931.6 EIM82088.1 - 0.43 10.8 1.9 5.1 7.3 0.3 2.9 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 Cauli_VI PF01693.16 EIM82092.1 - 0.00075 19.8 0.9 0.0016 18.7 0.2 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin KDZ PF18758.1 EIM82093.1 - 2e-46 158.4 0.0 7e-46 156.6 0.0 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Saf_2TM PF18303.1 EIM82094.1 - 0.00014 21.4 0.7 0.00051 19.6 0.2 1.9 2 0 0 2 2 2 1 SAVED-fused 2TM effector domain Ost5 PF05251.12 EIM82094.1 - 0.2 12.0 0.2 0.2 12.0 0.2 2.7 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 FA_desaturase PF00487.24 EIM82095.1 - 3.4e-21 76.2 23.6 6.9e-21 75.2 23.6 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EIM82095.1 - 0.0025 18.0 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF5527 PF17665.1 EIM82095.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) SNF2_N PF00176.23 EIM82098.1 - 1.5e-59 201.5 1.8 1e-58 198.8 1.8 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM82098.1 - 7.1e-14 52.1 0.0 2e-12 47.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EIM82098.1 - 1.3e-09 37.9 3.6 2.8e-09 36.9 3.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM82098.1 - 3.7e-09 36.3 2.0 3.7e-09 36.3 2.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM82098.1 - 1.9e-08 34.1 5.4 4.2e-08 33.0 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM82098.1 - 2.1e-08 33.9 6.4 4.2e-08 32.9 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM82098.1 - 2.4e-07 30.5 6.1 6.3e-07 29.2 6.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM82098.1 - 2.5e-06 27.7 5.8 5.9e-06 26.5 5.8 1.7 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 EIM82098.1 - 1.3e-05 25.2 0.0 3.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 EIM82098.1 - 0.0002 21.5 4.4 0.00054 20.1 4.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EIM82098.1 - 0.00027 20.7 5.3 0.0027 17.5 5.3 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EIM82098.1 - 0.0026 17.5 6.5 0.0067 16.1 6.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger AAA_34 PF13872.6 EIM82098.1 - 0.0079 15.1 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 FYVE PF01363.21 EIM82098.1 - 0.02 15.0 2.3 0.048 13.8 2.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.7 EIM82098.1 - 0.03 14.6 0.9 0.083 13.2 0.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-4CXXC_R1 PF10497.9 EIM82098.1 - 0.067 13.4 0.9 0.2 11.9 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Pox_A_type_inc PF04508.12 EIM82098.1 - 0.17 11.8 1.5 0.62 10.0 1.5 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat zf-ANAPC11 PF12861.7 EIM82098.1 - 0.59 10.2 1.9 6.3 6.9 1.5 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EIM82098.1 - 1.5 8.7 5.3 3.8 7.4 5.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PRKG1_interact PF15898.5 EIM82098.1 - 10 7.1 13.4 0.75 10.7 5.6 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Mito_carr PF00153.27 EIM82099.1 - 6.8e-57 189.4 0.8 4.8e-20 71.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_16 PF00722.21 EIM82100.1 - 0.0015 18.1 0.1 0.0028 17.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ADH_zinc_N PF00107.26 EIM82101.1 - 6.9e-16 58.4 0.0 1.9e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82101.1 - 1.1e-08 34.9 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM82101.1 - 9.1e-06 26.8 0.0 1.5e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM82101.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase APH PF01636.23 EIM82102.1 - 4.8e-15 56.1 0.0 6.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family MazG PF03819.17 EIM82102.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Git3 PF11710.8 EIM82103.1 - 2.2e-05 24.3 9.9 4e-05 23.5 9.9 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 LRR_1 PF00560.33 EIM82104.1 - 0.032 14.7 1.4 18 6.4 0.0 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.7 EIM82104.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like JIP_LZII PF16471.5 EIM82104.1 - 0.14 12.4 0.3 0.25 11.5 0.3 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II LRR_4 PF12799.7 EIM82104.1 - 0.49 10.9 3.8 13 6.3 0.1 3.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) DSPc PF00782.20 EIM82106.1 - 0.00094 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EIM82106.1 - 0.017 15.2 0.2 0.84 9.7 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EIM82106.1 - 0.038 14.0 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PBP1_TM PF14812.6 EIM82106.1 - 0.47 10.9 0.0 0.47 10.9 0.0 2.8 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SR-25 PF10500.9 EIM82106.1 - 2 8.0 30.1 0.025 14.2 20.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_19 PF14559.6 EIM82108.1 - 6.6e-12 45.8 13.7 0.00032 21.2 0.2 8.6 8 1 3 11 11 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM82108.1 - 4.8e-10 38.8 15.1 1.3 9.3 0.1 9.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIM82108.1 - 1.2e-09 37.6 5.3 0.54 10.2 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM82108.1 - 5.4e-08 32.3 12.7 0.056 13.5 0.2 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82108.1 - 1.1e-07 32.0 23.8 0.015 15.6 0.3 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIM82108.1 - 1.2e-06 28.0 0.4 0.0061 16.2 0.0 4.7 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 EIM82108.1 - 1.4e-06 28.1 10.1 2.9 8.3 0.0 8.1 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM82108.1 - 9.4e-06 26.2 23.8 0.0081 16.8 1.9 7.1 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EIM82108.1 - 0.00055 20.4 9.7 49 4.9 0.0 8.1 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82108.1 - 0.0034 18.1 25.1 3 8.9 0.4 9.6 9 2 3 12 12 11 1 Tetratricopeptide repeat TPR_20 PF14561.6 EIM82108.1 - 0.0044 17.3 6.2 0.28 11.5 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat SNAP PF14938.6 EIM82108.1 - 0.0047 16.4 6.6 0.2 11.0 0.4 2.7 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 EIM82108.1 - 0.0071 16.6 3.0 53 4.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EIM82108.1 - 0.017 15.6 3.3 2.8 8.4 0.1 4.1 4 1 0 4 4 4 0 Alkyl sulfatase dimerisation TPR_9 PF13371.6 EIM82108.1 - 0.14 12.3 4.3 3.4 7.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM82108.1 - 0.51 10.3 8.1 26 4.9 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat PilJ PF13675.6 EIM82108.1 - 1.6 8.8 4.6 0.7 9.9 1.1 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ANAPC3 PF12895.7 EIM82108.1 - 2.8 8.2 16.4 0.11 12.7 1.6 5.1 5 2 2 7 7 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TspO_MBR PF03073.15 EIM82109.1 - 2.6e-46 157.0 9.0 3.3e-46 156.7 9.0 1.1 1 0 0 1 1 1 1 TspO/MBR family CBS PF00571.28 EIM82110.1 - 7.5e-09 35.9 0.0 0.0017 18.8 0.0 2.2 2 0 0 2 2 2 2 CBS domain DUF2034 PF10356.9 EIM82111.1 - 2.8e-17 62.8 0.2 3.4e-07 29.9 0.0 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EIM82111.1 - 3.7e-06 26.9 0.0 9.3e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease Glyco_hydro_43 PF04616.14 EIM82112.1 - 1.1e-41 143.1 5.3 1.2e-41 142.9 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Tyrosinase PF00264.20 EIM82113.1 - 3.5e-32 112.5 7.0 5.1e-32 112.0 7.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Mito_carr PF00153.27 EIM82114.1 - 3.6e-68 225.5 0.6 1.1e-21 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIM82114.1 - 0.1 11.7 0.1 12 4.9 0.1 2.8 2 1 1 3 3 3 0 Gammaproteobacterial serine protease G-alpha PF00503.20 EIM82115.1 - 4.4e-115 384.6 0.0 5.1e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM82115.1 - 5.6e-08 32.4 0.1 6.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 EIM82115.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EIM82115.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 EIM82115.1 - 0.065 13.4 0.0 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EIM82115.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FA_desaturase PF00487.24 EIM82116.1 - 1.8e-15 57.5 26.8 2.8e-15 56.9 26.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIM82116.1 - 1.1e-12 47.8 0.0 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ADH_zinc_N PF00107.26 EIM82117.1 - 5.5e-13 49.0 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82117.1 - 4.8e-09 36.1 0.0 8.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM82117.1 - 3.6e-05 24.8 0.0 5.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EIM82118.1 - 5.6e-16 58.7 0.0 1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82118.1 - 5.8e-09 35.8 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM82118.1 - 8.2e-05 23.7 0.0 0.00014 22.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AAA PF00004.29 EIM82119.1 - 1.4e-14 54.7 0.0 3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM82119.1 - 9.2e-10 39.2 0.0 3.1e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM82119.1 - 3e-06 27.6 0.0 5.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 EIM82119.1 - 3.2e-05 24.0 0.1 8.5e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain BAH PF01426.18 EIM82119.1 - 5.9e-05 22.9 0.0 0.0024 17.7 0.0 2.6 2 0 0 2 2 2 1 BAH domain DUF2075 PF09848.9 EIM82119.1 - 0.00015 21.2 0.0 0.0005 19.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EIM82119.1 - 0.00082 19.7 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EIM82119.1 - 0.029 14.3 0.0 0.15 11.9 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EIM82119.1 - 0.054 13.3 1.6 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EIM82119.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EIM82119.1 - 0.079 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 EIM82119.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain CDC45 PF02724.14 EIM82119.1 - 7.8 4.6 11.4 17 3.6 11.4 1.5 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.31 EIM82120.1 - 2.8e-07 30.8 0.0 5.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ADH_zinc_N PF00107.26 EIM82121.1 - 6.8e-14 52.0 0.0 2e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82121.1 - 4.4e-06 27.8 0.0 7.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82121.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CbiG_N PF11760.8 EIM82121.1 - 0.027 14.4 0.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal ECR1_N PF14382.6 EIM82122.1 - 7.2e-16 57.7 0.3 1.3e-15 56.9 0.3 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EIM82122.1 - 7.6e-14 51.8 0.1 1.5e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EIM82122.1 - 0.049 14.2 0.1 1.1 9.9 0.1 2.4 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 Sda PF08970.10 EIM82122.1 - 0.12 12.1 0.8 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Sporulation inhibitor A Lactamase_B PF00753.27 EIM82123.1 - 2.5e-07 30.9 0.1 4.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIM82123.1 - 0.00061 19.4 0.1 0.0016 18.0 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain ATP19 PF11022.8 EIM82125.1 - 5.2e-17 62.0 0.5 7.5e-17 61.5 0.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit K Abhydrolase_6 PF12697.7 EIM82126.1 - 6.3e-10 40.0 5.9 2.7e-09 38.0 5.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EIM82127.1 - 1.4e-09 38.9 4.6 3.9e-09 37.4 4.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM82127.1 - 0.001 18.8 0.0 0.0069 16.1 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4350 PF14258.6 EIM82127.1 - 0.02 15.3 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Hydrolase_4 PF12146.8 EIM82127.1 - 0.024 13.9 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EIM82127.1 - 0.031 14.1 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase Lipase3_N PF03893.16 EIM82127.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase 3 N-terminal region Abhydrolase_6 PF12697.7 EIM82128.1 - 2.6e-10 41.3 3.3 1.3e-09 39.0 2.6 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EIM82129.1 - 1.5e-08 35.5 2.4 4.6e-08 33.9 2.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM82129.1 - 0.093 12.4 0.1 0.69 9.5 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_16 PF00722.21 EIM82130.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RPN1_RPN2_N PF17781.1 EIM82132.1 - 2.2e-110 368.9 0.0 3.4e-110 368.3 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EIM82132.1 - 5.1e-30 103.3 0.2 1.2e-29 102.1 0.0 1.8 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EIM82132.1 - 8e-18 63.9 19.3 0.00035 20.9 0.5 8.6 9 0 0 9 9 9 5 Proteasome/cyclosome repeat IBR PF01485.21 EIM82134.1 - 1.5e-14 54.0 34.1 7.2e-08 32.5 6.8 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EIM82134.1 - 1.5e-07 31.3 4.9 1.5e-07 31.3 4.9 3.6 2 1 0 2 2 1 1 RING-type zinc-finger RRM_1 PF00076.22 EIM82134.1 - 2.5e-07 30.4 0.0 1.8e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 EIM82134.1 - 5.1e-07 29.5 0.4 5.1e-07 29.5 0.4 4.1 3 2 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM82134.1 - 2.2e-06 27.7 4.5 2.2e-06 27.7 4.5 3.6 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EIM82134.1 - 2.1e-05 24.3 2.0 2.1e-05 24.3 2.0 3.9 3 2 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 EIM82134.1 - 5.3e-05 23.9 0.4 0.26 12.0 0.1 2.6 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EIM82134.1 - 0.0001 22.5 2.3 0.0018 18.5 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-C3HC4_3 PF13920.6 EIM82134.1 - 0.00018 21.3 1.2 0.00018 21.3 1.2 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM82134.1 - 0.0013 18.6 5.6 0.0013 18.6 5.6 3.9 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EIM82134.1 - 0.0038 17.5 4.4 0.0038 17.5 4.4 4.4 3 1 1 4 4 2 1 Ring finger domain RRM_5 PF13893.6 EIM82134.1 - 0.0048 16.5 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TrmO_C PF18389.1 EIM82134.1 - 0.15 12.2 0.5 0.92 9.7 0.0 2.3 1 1 1 2 2 2 0 TrmO C-terminal domain zf-CCCH PF00642.24 EIM82134.1 - 3.4 7.7 14.2 0.041 13.8 2.6 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) APH PF01636.23 EIM82135.1 - 3e-16 60.1 0.0 4.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM82135.1 - 0.00056 19.5 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EIM82135.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 EIM82135.1 - 0.29 9.9 0.0 0.55 9.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) NUC153 PF08159.12 EIM82136.1 - 1.4e-11 44.0 0.2 3.5e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 NUC153 domain Nop14 PF04147.12 EIM82136.1 - 0.013 13.8 13.6 0.022 13.0 13.6 1.3 1 0 0 1 1 1 0 Nop14-like family NARP1 PF12569.8 EIM82136.1 - 6.4 5.6 10.0 11 4.7 10.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MOR2-PAG1_N PF14222.6 EIM82137.1 - 2.7e-158 528.3 0.0 1.3e-157 526.1 0.0 2.2 2 1 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EIM82137.1 - 1.6e-87 293.6 0.1 3.9e-87 292.3 0.1 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EIM82137.1 - 1.7e-17 62.4 0.7 3.2e-13 48.3 0.0 3.0 3 0 0 3 3 3 2 Cell morphogenesis central region Mlh1_C PF16413.5 EIM82138.1 - 3.4e-92 308.7 1.5 8.8e-91 304.0 0.2 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EIM82138.1 - 5.6e-27 93.8 0.3 1.1e-26 92.8 0.3 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EIM82138.1 - 8.8e-12 45.0 0.0 2.4e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EIM82138.1 - 6.3e-07 29.9 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YqeY PF09424.10 EIM82138.1 - 0.045 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Yqey-like protein RdRP PF05183.12 EIM82139.1 - 5.9e-112 375.2 0.0 8.6e-112 374.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase MOR2-PAG1_C PF14225.6 EIM82139.1 - 2.7e-18 66.7 0.0 6.2e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal RdRP PF05183.12 EIM82140.1 - 2.4e-124 416.2 0.0 3e-124 415.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Cyt_b-c1_8 PF10890.8 EIM82140.1 - 0.014 15.8 0.0 2.8 8.4 0.0 2.9 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 PRANC PF09372.10 EIM82140.1 - 0.3 11.5 0.7 1.2 9.5 0.0 2.4 3 0 0 3 3 3 0 PRANC domain Aldo_ket_red PF00248.21 EIM82141.1 - 3e-42 144.8 0.0 3.3e-32 111.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DJ-1_PfpI PF01965.24 EIM82142.1 - 7.8e-38 129.9 0.0 8.9e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EIM82142.1 - 0.031 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 EIM82142.1 - 0.039 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like DUF4139 PF13598.6 EIM82143.1 - 1.1e-28 100.4 0.0 6.2e-28 98.0 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EIM82143.1 - 5.1e-11 42.9 2.3 6.1e-10 39.4 0.0 3.0 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) FXMRP1_C_core PF12235.8 EIM82143.1 - 0.16 12.6 1.6 0.98 10.1 0.1 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal zf-C3HC4_3 PF13920.6 EIM82144.1 - 2.7e-05 23.9 2.9 4.2e-05 23.3 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM82144.1 - 0.00033 20.5 5.5 0.00061 19.6 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 EIM82144.1 - 0.00039 20.2 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.6 EIM82144.1 - 0.00079 19.3 3.6 0.0016 18.4 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EIM82144.1 - 0.0021 18.4 4.9 0.0041 17.4 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM82144.1 - 0.0047 16.8 4.8 0.0098 15.7 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM82144.1 - 0.014 15.5 3.2 0.033 14.2 3.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Siva PF05458.12 EIM82144.1 - 0.12 12.1 3.2 0.22 11.2 3.2 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-C3HC4_2 PF13923.6 EIM82144.1 - 0.22 11.4 5.1 0.51 10.2 5.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EIM82144.1 - 0.27 11.4 4.0 0.59 10.3 4.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Med8 PF10232.9 EIM82145.1 - 0.096 12.3 2.9 0.13 11.8 2.9 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DNA_pol_phi PF04931.13 EIM82145.1 - 0.58 8.2 12.9 0.71 7.9 12.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi LAT PF15234.6 EIM82145.1 - 0.59 9.8 3.6 0.76 9.5 3.6 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells CENP-B_dimeris PF09026.10 EIM82145.1 - 1.2 9.5 15.0 2.4 8.6 15.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM178 PF14816.6 EIM82145.1 - 2.1 7.3 4.7 2.7 6.8 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Oxidored_FMN PF00724.20 EIM82147.1 - 2.9e-25 89.3 0.0 2.1e-24 86.4 0.0 1.8 1 1 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 EIM82148.1 - 6e-37 127.7 0.0 7.7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ProRS-C_1 PF09180.11 EIM82149.1 - 3.1e-25 88.2 0.3 7.1e-25 87.0 0.3 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EIM82149.1 - 5e-17 61.8 0.0 1.7e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EIM82149.1 - 1.7e-16 60.7 0.0 3.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EIM82149.1 - 7.3e-12 45.4 0.1 1.4e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Zn-ribbon_8 PF09723.10 EIM82149.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EIM82149.1 - 0.17 11.4 0.3 0.34 10.4 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain tRNA-synt_1 PF00133.22 EIM82150.1 - 2.7e-141 471.8 0.0 1.7e-140 469.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EIM82150.1 - 5.5e-25 88.1 0.3 1e-24 87.2 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EIM82150.1 - 2.1e-18 66.3 0.8 1.1e-12 47.4 0.1 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EIM82150.1 - 1e-05 25.0 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 EIM82150.1 - 0.0074 16.1 6.8 0.019 14.9 6.8 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1f PF01921.18 EIM82150.1 - 0.014 14.3 0.2 0.074 12.0 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 EIM82150.1 - 0.35 9.7 2.5 17 4.2 0.1 3.1 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Lactonase PF10282.9 EIM82151.1 - 4.9e-26 91.8 0.0 1.3e-25 90.5 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller TPR_1 PF00515.28 EIM82152.1 - 4e-09 35.9 4.1 1.2e-06 28.0 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM82152.1 - 4.8e-07 29.4 7.0 0.0036 17.3 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM82152.1 - 0.00018 21.5 2.8 0.00034 20.6 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM82152.1 - 0.0029 17.3 2.2 17 5.2 0.0 4.9 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 EIM82152.1 - 0.004 17.4 1.3 11 6.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82152.1 - 0.0041 17.8 1.4 6.6 7.8 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Cyclin_N PF00134.23 EIM82153.1 - 4.1e-45 152.6 0.6 4.1e-45 152.6 0.6 2.1 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIM82153.1 - 1.2e-26 93.2 0.1 2.2e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain ABC_membrane_2 PF06472.15 EIM82154.1 - 2.7e-77 259.8 0.3 5e-77 258.9 0.1 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EIM82154.1 - 4.9e-16 59.5 0.0 9.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 EIM82154.1 - 0.085 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 EIM82154.1 - 0.21 11.0 0.0 0.96 8.8 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MatE PF01554.18 EIM82155.1 - 2.5e-48 163.8 33.0 3.9e-26 91.6 8.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EIM82155.1 - 5.1e-06 26.6 7.9 5.1e-06 26.6 7.9 4.0 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MHC2-interact PF09307.10 EIM82155.1 - 0.32 11.0 1.0 0.86 9.6 0.1 2.1 2 0 0 2 2 2 0 CLIP, MHC2 interacting AMP-binding PF00501.28 EIM82156.1 - 2.4e-91 306.5 0.0 2.9e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM82156.1 - 1.3e-11 45.3 0.0 4.2e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Snurportin1 PF11538.8 EIM82157.1 - 0.0054 16.9 8.2 0.01 16.0 8.2 1.5 1 0 0 1 1 1 1 Snurportin1 Ribosomal_L16 PF00252.18 EIM82158.1 - 1.8e-36 125.0 0.1 2.5e-36 124.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PRP3 PF08572.10 EIM82159.1 - 6.3e-19 68.6 0.5 1.2e-18 67.7 0.1 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EIM82160.1 - 2.6e-43 147.6 0.6 6.3e-43 146.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 EIM82160.1 - 1.2e-30 106.9 8.4 2.2e-30 106.1 8.4 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) SURF4 PF02077.15 EIM82161.1 - 1.2e-94 316.9 6.5 1.3e-94 316.7 6.5 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 EIM82161.1 - 1.5 8.8 5.6 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HhH-GPD PF00730.25 EIM82163.1 - 2.1e-19 70.0 0.0 4.1e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EIM82163.1 - 3.3e-10 39.9 0.0 2.1e-08 34.1 0.0 2.7 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.23 EIM82163.1 - 0.00034 20.3 0.0 0.00096 18.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EIM82163.1 - 0.017 15.5 7.0 0.042 14.2 7.0 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DTHCT PF08070.11 EIM82163.1 - 1 10.1 5.0 0.32 11.7 1.1 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region TAL_FSA PF00923.19 EIM82164.1 - 3.3e-45 154.6 0.2 4.6e-45 154.2 0.2 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SIN1_PH PF16979.5 EIM82166.1 - 4e-32 110.7 0.3 7.5e-32 109.9 0.3 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 EIM82166.1 - 3.6e-12 46.6 0.2 1.2e-11 44.9 0.1 2.0 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain TUG-UBL1 PF11470.8 EIM82166.1 - 3.5e-05 23.9 0.0 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 EIM82166.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain RA PF00788.23 EIM82166.1 - 0.021 15.5 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain AAA PF00004.29 EIM82170.1 - 0.0064 16.9 0.3 0.024 15.1 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 EIM82170.1 - 0.0088 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DEAD PF00270.29 EIM82170.1 - 0.076 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UPF0524 PF15823.5 EIM82170.1 - 1.5 8.1 4.5 2.9 7.2 4.5 1.5 1 0 0 1 1 1 0 UPF0524 of C3orf70 BTB PF00651.31 EIM82171.1 - 2.1e-07 31.1 0.0 4.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AbiEi_3_N PF17194.4 EIM82171.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain DDE_3 PF13358.6 EIM82174.1 - 3.8e-08 33.2 0.0 4e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIM82175.1 - 3.3e-08 33.4 0.1 5.5e-08 32.7 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease CRM1_repeat_2 PF18784.1 EIM82175.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Nop14 PF04147.12 EIM82176.1 - 0.48 8.6 36.8 0.0079 14.5 29.3 1.7 2 0 0 2 2 2 0 Nop14-like family VID27 PF08553.10 EIM82178.1 - 1.4e-37 129.6 0.0 1.7e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain DEAD PF00270.29 EIM82179.1 - 3.8e-09 36.5 0.0 4e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 EIM82179.1 - 0.056 12.2 0.0 0.065 12.0 0.0 1.0 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Helicase_C PF00271.31 EIM82180.1 - 4.3e-29 101.1 0.0 1.5e-27 96.1 0.0 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM82180.1 - 0.0043 16.8 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase HTH_Tnp_Tc5 PF03221.16 EIM82181.1 - 3e-06 27.2 0.0 3.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 EIM82182.1 - 9.6e-06 25.4 0.0 1.1e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIM82184.1 - 0.13 12.5 0.2 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Transposase HTH_23 PF13384.6 EIM82184.1 - 0.17 11.7 0.2 0.46 10.3 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain YceD PF02620.17 EIM82186.1 - 0.1 12.7 0.1 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD BST2 PF16716.5 EIM82189.1 - 0.0042 17.6 0.6 0.0069 16.9 0.6 1.3 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 FliT PF05400.13 EIM82189.1 - 0.044 14.6 0.4 0.068 14.0 0.4 1.3 1 0 0 1 1 1 0 Flagellar protein FliT FlxA PF14282.6 EIM82189.1 - 1.3 9.0 7.5 0.081 12.9 2.3 1.7 2 0 0 2 2 2 0 FlxA-like protein Sortilin-Vps10 PF15902.5 EIM82191.1 - 2.9e-13 49.4 2.9 0.00041 19.3 0.0 5.2 3 2 1 5 5 5 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 EIM82191.1 - 1.2e-08 33.7 27.8 0.25 11.5 0.2 8.8 8 0 0 8 8 8 4 BNR/Asp-box repeat BNR_2 PF13088.6 EIM82191.1 - 0.0012 18.2 7.1 2.8 7.2 0.7 5.6 3 2 0 4 4 4 2 BNR repeat-like domain BNR_6 PF15899.5 EIM82191.1 - 0.1 12.7 2.1 83 3.7 0.0 4.9 4 0 0 4 4 4 0 BNR-Asp box repeat Glyco_hydro_3_C PF01915.22 EIM82192.1 - 9.4e-49 166.1 0.0 1.5e-48 165.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM82192.1 - 3e-35 122.1 0.0 1.8e-34 119.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM82192.1 - 2.8e-22 78.6 0.0 5.3e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain BTB PF00651.31 EIM82193.1 - 1.7e-09 37.9 0.0 4.4e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain ketoacyl-synt PF00109.26 EIM82194.1 - 8.3e-57 192.6 2.7 9e-57 192.5 0.7 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EIM82194.1 - 2e-39 135.9 0.0 3.4e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EIM82194.1 - 5.6e-38 130.6 0.0 1.6e-37 129.2 0.0 1.8 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EIM82194.1 - 2.2e-28 98.6 0.1 6.6e-28 97.1 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EIM82194.1 - 5.7e-25 88.2 0.0 1.1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 EIM82194.1 - 1e-20 74.8 0.0 3.1e-20 73.3 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 EIM82194.1 - 9.9e-12 45.3 0.0 5.2e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EIM82194.1 - 9.9e-11 42.3 0.0 3e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM82194.1 - 1.8e-10 40.9 0.0 4.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EIM82194.1 - 4.4e-09 36.1 0.2 8.1e-08 31.9 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82194.1 - 1.7e-08 35.6 0.5 1.5e-07 32.5 0.0 2.9 2 1 1 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 EIM82194.1 - 2.5e-08 34.4 0.0 1.7e-07 31.8 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM82194.1 - 6.2e-08 32.6 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EIM82194.1 - 7.1e-08 32.7 0.1 1.9e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EIM82194.1 - 3.7e-07 30.8 0.0 3.5e-06 27.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 EIM82194.1 - 2.6e-05 23.7 0.0 0.00024 20.6 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 EIM82194.1 - 0.00028 20.5 0.0 0.0011 18.5 0.0 2.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 EIM82194.1 - 0.0012 18.7 2.3 0.041 13.7 2.3 3.1 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF938 PF06080.12 EIM82194.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) ADH_zinc_N PF00107.26 EIM82194.1 - 0.0052 16.8 0.0 0.025 14.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_24 PF13578.6 EIM82194.1 - 0.014 16.4 0.0 0.11 13.6 0.0 2.6 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 EIM82194.1 - 0.022 13.8 0.2 0.056 12.4 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 EIM82194.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Epimerase PF01370.21 EIM82194.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 EIM82195.1 - 0.00042 20.1 0.7 0.002 18.0 0.2 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EIM82195.1 - 0.0043 16.9 0.5 0.41 10.6 0.1 2.9 2 0 0 2 2 2 2 F-box domain zf-C2H2_jaz PF12171.8 EIM82196.1 - 0.061 13.6 6.7 0.1 12.9 3.2 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM82196.1 - 4.3 7.9 7.3 7.1 7.2 4.6 2.5 2 1 0 2 2 2 0 Zinc-finger of C2H2 type GCM PF03615.15 EIM82197.1 - 2.1e-07 30.9 0.1 4.6e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 GCM motif protein PHD PF00628.29 EIM82197.1 - 1.6e-06 27.9 4.6 3.8e-06 26.7 4.6 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIM82197.1 - 0.018 14.6 1.3 0.045 13.3 1.3 1.7 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 EIM82197.1 - 0.38 10.9 5.2 1.1 9.4 5.2 1.8 1 0 0 1 1 1 0 PHD-finger Peptidase_C14 PF00656.22 EIM82198.1 - 2.3e-13 50.7 0.0 3.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF4904 PF16247.5 EIM82198.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) Peptidase_C14 PF00656.22 EIM82199.1 - 2.8e-19 70.1 0.0 1.2e-18 68.0 0.0 1.9 1 1 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM82199.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 1 1 0 1 1 1 0 CHAT domain ZnuA PF01297.17 EIM82199.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF1752 PF08550.10 EIM82201.1 - 2.8e-13 49.4 1.2 3.5e-13 49.1 1.2 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GMC_oxred_N PF00732.19 EIM82202.1 - 1.9e-64 217.9 0.0 2.6e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM82202.1 - 3.3e-27 95.8 0.0 6.5e-27 94.8 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM82202.1 - 0.018 15.3 0.1 0.053 13.7 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM82202.1 - 0.13 11.3 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_A17 PF05380.13 EIM82204.1 - 0.088 12.8 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Pao retrotransposon peptidase DUF3464 PF11947.8 EIM82204.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CsbD PF05532.12 EIM82205.1 - 8.2e-16 57.7 16.8 4.6e-10 39.2 3.5 2.1 1 1 1 2 2 2 2 CsbD-like Chitin_synth_2 PF03142.15 EIM82207.1 - 1e-13 50.8 0.1 1.1e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EIM82207.1 - 2.2e-07 31.0 8.0 4.2e-07 30.1 8.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIM82207.1 - 1.2e-05 25.4 0.1 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EIM82207.1 - 7.8e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EIM82207.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 GPI-anchored PF10342.9 EIM82208.1 - 1.2e-05 26.0 0.0 3.2e-05 24.6 0.0 1.7 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RTA1 PF04479.13 EIM82209.1 - 4.8e-30 104.7 11.5 1.9e-20 73.3 7.3 4.1 3 1 1 4 4 4 2 RTA1 like protein Abhydrolase_1 PF00561.20 EIM82210.1 - 2.7e-28 99.3 0.0 5.5e-28 98.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM82210.1 - 4.5e-19 68.7 0.0 1.7e-18 66.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM82210.1 - 3.5e-18 67.0 0.0 4.4e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIM82210.1 - 2.9e-09 36.7 0.0 3e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EIM82210.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 EIM82210.1 - 0.00011 22.0 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.13 EIM82210.1 - 0.00033 20.4 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ser_hydrolase PF06821.13 EIM82210.1 - 0.0022 17.9 0.0 2.1 8.2 0.0 2.1 1 1 0 2 2 2 2 Serine hydrolase AXE1 PF05448.12 EIM82210.1 - 0.0023 16.6 0.0 0.0069 15.1 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EIM82210.1 - 0.011 15.6 0.0 0.06 13.2 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 EIM82210.1 - 0.046 12.9 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ndr PF03096.14 EIM82210.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.5 1 1 0 1 1 1 0 Ndr family Thioesterase PF00975.20 EIM82210.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.2 1 1 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 EIM82210.1 - 0.12 12.3 0.0 5.6 6.9 0.0 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) O-FucT PF10250.9 EIM82211.1 - 0.0021 17.9 0.0 0.0071 16.1 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aldedh PF00171.22 EIM82214.1 - 1.7e-138 462.0 0.0 2e-138 461.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM82214.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Flavin_Reduct PF01613.18 EIM82215.1 - 4.9e-14 52.7 0.0 7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Epimerase PF01370.21 EIM82216.1 - 1.3e-15 57.6 0.0 3.4e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM82216.1 - 3.4e-13 49.2 0.0 5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM82216.1 - 7.3e-07 28.9 0.0 1.6e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM82216.1 - 8.3e-07 29.1 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM82216.1 - 1.2e-05 24.6 0.0 0.00026 20.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EIM82216.1 - 0.0019 17.7 0.1 0.0034 16.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM82216.1 - 0.0048 16.8 0.1 0.17 11.8 0.1 2.3 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EIM82216.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Methyltransf_2 PF00891.18 EIM82217.1 - 9.7e-19 67.5 0.0 1.9e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EIM82217.1 - 0.00068 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EIM82217.1 - 0.048 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 EIM82217.1 - 0.22 11.3 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DOT1 PF08123.13 EIM82217.1 - 0.22 11.0 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 GMC_oxred_N PF00732.19 EIM82218.1 - 3.5e-112 374.6 0.0 5.4e-61 206.6 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM82218.1 - 3.6e-57 192.9 0.1 1.4e-32 113.2 0.0 3.5 3 0 0 3 3 3 3 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM82218.1 - 4.3e-08 32.6 8.5 3.6e-05 23.0 0.3 3.1 4 0 0 4 4 4 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIM82218.1 - 1.7e-07 30.8 1.2 0.0019 17.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM82218.1 - 1.6e-05 25.0 7.7 0.0089 16.2 0.7 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM82218.1 - 0.00016 21.0 1.4 0.31 10.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family TrkA_N PF02254.18 EIM82218.1 - 0.001 19.3 2.7 0.19 12.0 0.1 2.7 2 0 0 2 2 2 2 TrkA-N domain HI0933_like PF03486.14 EIM82218.1 - 0.0025 16.6 5.2 0.017 13.8 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 EIM82218.1 - 0.0033 16.7 4.0 0.024 13.9 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EIM82218.1 - 0.0069 15.5 1.5 0.0069 15.5 1.5 3.9 5 0 0 5 5 5 2 FAD binding domain NAD_binding_9 PF13454.6 EIM82218.1 - 0.019 14.9 1.9 1.9 8.5 0.0 3.0 3 0 0 3 3 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EIM82218.1 - 0.023 13.9 2.3 3.6 6.8 0.1 3.3 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM82218.1 - 0.14 11.7 14.3 0.54 9.8 2.0 3.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 EIM82218.1 - 0.36 9.8 1.3 8 5.4 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EIM82218.1 - 0.72 10.5 5.9 0.85 10.2 0.6 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM82218.1 - 4.8 5.9 9.2 1.7 7.4 0.6 2.9 4 0 0 4 4 4 0 Tryptophan halogenase NmrA PF05368.13 EIM82219.1 - 4.8e-14 52.5 0.0 2.1e-09 37.3 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EIM82219.1 - 2.5e-10 40.6 1.0 3.1e-08 33.7 1.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM82219.1 - 7.5e-06 26.2 0.1 1.6e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EIM82219.1 - 0.00057 19.4 0.0 0.057 12.9 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM82219.1 - 0.00063 18.8 0.1 0.00096 18.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EIM82219.1 - 0.0019 18.3 0.3 0.0036 17.4 0.3 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EIM82219.1 - 0.0036 17.5 0.3 0.0068 16.7 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain Ldh_1_N PF00056.23 EIM82219.1 - 0.0094 16.0 0.5 0.015 15.4 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EIM82219.1 - 0.013 16.1 0.2 0.028 15.0 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 EIM82219.1 - 0.027 15.1 0.3 0.058 14.1 0.3 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Biotin_carb_N PF00289.22 EIM82219.1 - 0.087 13.4 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain MMR_HSR1 PF01926.23 EIM82219.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase p450 PF00067.22 EIM82220.1 - 4.8e-69 233.3 0.0 6.6e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SASP_gamma PF04259.14 EIM82220.1 - 0.22 12.0 0.0 0.45 11.0 0.0 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore protein, gamma-type FAD_binding_4 PF01565.23 EIM82221.1 - 1.7e-22 79.7 0.1 3.8e-22 78.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EIM82221.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.19 EIM82222.1 - 4e-53 180.7 0.0 5.8e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM82222.1 - 1.2e-28 100.4 0.0 2e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM82222.1 - 0.0006 20.0 0.1 0.0017 18.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM82222.1 - 0.0012 18.0 1.9 0.0042 16.2 0.2 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EIM82222.1 - 0.039 14.0 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EIM82222.1 - 0.055 12.7 0.1 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM82222.1 - 0.074 12.6 0.6 0.12 11.9 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EIM82222.1 - 0.087 12.0 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EIM82222.1 - 0.11 11.1 0.2 0.77 8.4 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EIM82222.1 - 0.15 11.1 0.2 0.25 10.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EIM82222.1 - 0.21 10.8 0.2 0.32 10.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Terpene_synth_C PF03936.16 EIM82223.1 - 2.1e-05 24.0 0.0 4.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 EIM82224.1 - 4.1e-48 164.3 0.0 5e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82225.1 - 1.5e-14 53.7 0.0 1.6e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82226.1 - 4.3e-51 174.1 0.0 5.1e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82227.1 - 1.8e-12 46.8 0.0 2e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EIM82228.1 - 2.8e-14 53.2 0.0 5.6e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82228.1 - 3.9e-06 26.7 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM82228.1 - 1.4e-05 26.1 0.0 3.7e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase zf-UBP PF02148.19 EIM82229.1 - 0.007 16.7 0.0 0.027 14.8 0.0 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF1938 PF09153.10 EIM82229.1 - 0.031 14.4 1.5 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) TisB_toxin PF13939.6 EIM82229.1 - 2 8.3 9.6 10 6.0 1.5 2.8 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system DUF5134 PF17197.4 EIM82229.1 - 2.7 7.9 5.8 23 4.9 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) SAD_SRA PF02182.17 EIM82230.1 - 7.7e-43 145.9 0.1 9.4e-43 145.6 0.1 1.1 1 0 0 1 1 1 1 SAD/SRA domain BTB PF00651.31 EIM82231.1 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CAF1-p150_C2 PF15539.6 EIM82231.1 - 0.11 12.0 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term NAD_binding_4 PF07993.12 EIM82232.1 - 3.1e-24 85.5 0.0 5.8e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EIM82232.1 - 1.3e-08 34.6 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM82232.1 - 0.08 12.8 0.1 0.31 10.9 0.0 2.0 3 0 0 3 3 3 0 KR domain Semialdhyde_dh PF01118.24 EIM82232.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Phage_lysis PF03245.13 EIM82233.1 - 0.14 12.2 0.1 0.26 11.4 0.1 1.4 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Mg_trans_NIPA PF05653.14 EIM82234.1 - 6.5e-88 294.7 12.7 7.7e-88 294.4 12.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EIM82234.1 - 0.0026 17.9 3.6 0.0026 17.9 3.6 3.4 3 1 0 3 3 3 2 EamA-like transporter family Acyl_transf_3 PF01757.22 EIM82234.1 - 0.16 11.0 11.1 4.1 6.4 10.3 2.4 1 1 0 1 1 1 0 Acyltransferase family Dimer_Tnp_hAT PF05699.14 EIM82236.1 - 1e-12 47.7 0.1 1.1e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFIIF_alpha PF05793.12 EIM82237.1 - 7.3 5.0 40.0 2.4 6.6 21.9 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Plavaka PF18759.1 EIM82238.1 - 2.5e-34 119.0 0.0 6.4e-34 117.6 0.0 1.7 1 1 0 1 1 1 1 Plavaka transposase zf_C2HC_14 PF18574.1 EIM82238.1 - 1.6 8.6 4.5 6.2 6.7 2.4 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain K_oxygenase PF13434.6 EIM82240.1 - 3.5e-11 42.8 0.0 8.3e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EIM82240.1 - 3.1e-10 39.1 0.2 1.3e-09 37.1 0.2 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM82240.1 - 0.0001 21.6 0.0 0.056 12.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM82240.1 - 0.0053 16.0 0.0 0.065 12.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM82240.1 - 0.0081 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM82240.1 - 0.27 11.2 2.7 26 4.8 0.0 3.7 4 1 0 4 4 4 0 FAD-NAD(P)-binding ADH_N PF08240.12 EIM82242.1 - 1e-26 92.9 0.2 1.6e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM82242.1 - 3.8e-20 72.2 0.0 6.2e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM82242.1 - 2.3e-11 43.6 1.1 3.3e-10 39.8 1.1 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIM82242.1 - 3e-05 25.1 0.1 5.6e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 EIM82242.1 - 0.056 13.5 0.1 4.1 7.4 0.1 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short_C2 PF13561.6 EIM82242.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MGC-24 PF05283.11 EIM82243.1 - 0.0047 17.4 2.2 0.014 15.8 2.2 1.7 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 EIM82244.1 - 1.2e-39 136.3 0.0 1.5e-17 63.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82244.1 - 4.4e-11 42.6 0.0 0.00073 18.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Rrn6 PF10214.9 EIM82244.1 - 0.0059 15.2 0.0 0.0087 14.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor PrmA PF06325.13 EIM82244.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_ser-thr_kin PF05445.11 EIM82244.1 - 0.29 10.1 0.0 0.42 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DBR1 PF05011.13 EIM82245.1 - 1.5e-05 25.4 0.1 1.6e-05 25.4 0.1 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Goodbye PF17109.5 EIM82246.1 - 1.4e-18 67.5 3.1 8.5e-16 58.5 0.0 3.2 2 1 1 3 3 3 2 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EIM82246.1 - 9.2e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 EIM82246.1 - 2.5e-09 37.6 0.2 1.4e-05 25.6 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIM82246.1 - 0.00012 22.2 0.0 2.4 9.0 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat AAA_16 PF13191.6 EIM82246.1 - 0.00013 22.4 0.2 0.0015 18.9 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Ank PF00023.30 EIM82246.1 - 0.00022 21.5 0.0 0.91 10.1 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EIM82246.1 - 0.0013 19.0 0.1 0.37 11.2 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIM82246.1 - 0.0017 18.9 0.0 1.1 9.9 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF2075 PF09848.9 EIM82246.1 - 0.018 14.3 0.2 0.054 12.7 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EIM82246.1 - 0.021 15.1 0.1 0.083 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIM82246.1 - 0.039 14.3 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 EIM82246.1 - 0.11 12.9 0.1 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NBD_C PF17042.5 EIM82246.1 - 0.57 10.7 4.9 0.75 10.3 2.2 2.3 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain ADH_N PF08240.12 EIM82247.1 - 8e-25 86.8 1.2 1.3e-24 86.2 1.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM82247.1 - 3.2e-18 66.0 0.0 4.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM82247.1 - 2.1e-08 33.9 1.6 6.4e-07 29.1 1.6 2.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIM82247.1 - 0.00037 21.6 0.1 0.00065 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PARP PF00644.20 EIM82248.1 - 1.1e-11 44.7 0.1 1.6e-09 37.7 0.1 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Cul7 PF11515.8 EIM82248.1 - 0.33 11.3 1.6 19 5.6 0.1 2.6 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 DUF5016 PF16408.5 EIM82248.1 - 5.1 7.1 4.9 15 5.6 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5016) RIO1 PF01163.22 EIM82249.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.11 EIM82249.1 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 EIM82249.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 EIM82249.1 - 0.069 13.1 0.2 0.093 12.6 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family GST_C_3 PF14497.6 EIM82250.1 - 7.2e-27 93.5 0.3 1.5e-26 92.5 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM82250.1 - 9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM82250.1 - 0.0045 17.3 0.1 0.19 12.1 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 EIM82250.1 - 0.1 13.0 0.0 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DBR1 PF05011.13 EIM82251.1 - 2.3e-38 131.7 0.2 4e-38 131.0 0.2 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EIM82251.1 - 5.6e-08 33.5 0.1 8.9e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM82251.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-C2H2 PF00096.26 EIM82254.1 - 1e-06 28.9 14.2 0.00014 22.1 1.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM82254.1 - 0.0004 20.7 3.8 0.0004 20.7 3.8 2.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM82254.1 - 0.00065 20.3 9.6 0.083 13.8 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EIM82254.1 - 1.6 8.5 4.7 8.1 6.3 1.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Neisseria_TspB PF05616.13 EIM82254.1 - 6.7 5.1 7.9 16 3.9 7.9 1.5 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein LRR_4 PF12799.7 EIM82256.1 - 7e-05 23.1 8.2 3.7 8.1 0.7 6.2 4 2 4 8 8 8 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EIM82256.1 - 0.00046 20.0 5.4 35 4.8 0.0 6.2 6 0 0 6 6 6 1 Leucine Rich repeat TFIIF_alpha PF05793.12 EIM82256.1 - 2 6.9 17.5 3 6.3 17.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPL5 PF18168.1 EIM82256.1 - 5.4 6.2 7.9 8.4 5.6 7.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 LRR_8 PF13855.6 EIM82256.1 - 9.7 6.0 7.1 3.9 7.3 0.0 4.0 6 0 0 6 6 6 0 Leucine rich repeat PARP PF00644.20 EIM82257.1 - 8.6e-10 38.5 0.0 1.5e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Pkinase PF00069.25 EIM82258.1 - 1.5e-25 90.1 0.3 1.7e-25 89.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82258.1 - 6.6e-15 55.1 0.0 7.5e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM82258.1 - 3.7e-06 26.5 0.0 4.6e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM82258.1 - 0.00028 20.3 0.2 0.00029 20.3 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIM82258.1 - 0.005 16.5 0.4 0.0061 16.2 0.4 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM82258.1 - 0.0053 16.7 0.6 0.0066 16.4 0.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM82258.1 - 0.029 13.9 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EIM82258.1 - 0.073 12.0 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EIM82258.1 - 0.08 11.7 0.1 0.09 11.5 0.1 1.0 1 0 0 1 1 1 0 Fungal protein kinase Yae1_N PF09811.9 EIM82259.1 - 0.038 13.7 0.4 0.067 12.9 0.4 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Rx_N PF18052.1 EIM82259.1 - 1.9 8.8 6.0 3.6 7.9 6.0 1.4 1 0 0 1 1 1 0 Rx N-terminal domain DUF3584 PF12128.8 EIM82259.1 - 5.5 4.4 17.3 7.6 3.9 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_12 PF13424.6 EIM82260.1 - 0.012 15.9 8.8 0.54 10.6 0.2 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM82260.1 - 0.29 11.0 1.7 31 4.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82260.1 - 2.4 9.2 4.9 9.8 7.3 0.2 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat zf-MYND PF01753.18 EIM82261.1 - 0.0054 16.8 7.0 0.016 15.3 7.0 1.9 1 1 0 1 1 1 1 MYND finger Pro-kuma_activ PF09286.11 EIM82265.1 - 2.9e-35 121.7 0.6 5.7e-23 81.8 0.1 3.0 3 1 1 4 4 4 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM82265.1 - 8.1e-08 31.9 2.4 1.4e-07 31.1 2.4 1.4 1 0 0 1 1 1 1 Subtilase family PhageMin_Tail PF10145.9 EIM82265.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Phage-related minor tail protein Peptidase_C30 PF05409.13 EIM82265.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 Pro-kuma_activ PF09286.11 EIM82266.1 - 1.5e-37 129.1 0.1 5.1e-37 127.3 0.0 2.0 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM82266.1 - 2.1e-07 30.5 0.1 4.3e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 Subtilase family ALMS_repeat PF18727.1 EIM82266.1 - 0.12 12.3 0.1 0.36 10.7 0.1 1.9 1 0 0 1 1 1 0 Alstrom syndrome repeat DcrB PF08786.11 EIM82269.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 2 0 0 2 2 2 0 DcrB MFS_1 PF07690.16 EIM82270.1 - 4.4e-41 141.0 31.6 5.9e-41 140.6 31.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM82270.1 - 6.5e-12 45.0 17.3 3.3e-11 42.7 17.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EIM82270.1 - 0.0025 16.2 7.6 0.021 13.1 1.2 2.9 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Mcp5_PH PF12814.7 EIM82270.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology ECF_trnsprt PF12822.7 EIM82272.1 - 4.8 7.2 16.1 10 6.2 2.3 3.0 1 1 2 3 3 3 0 ECF transporter, substrate-specific component C2 PF00168.30 EIM82273.1 - 2.9e-16 59.6 0.0 4.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF167 PF02594.16 EIM82273.1 - 0.19 11.9 0.0 0.51 10.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 BTB PF00651.31 EIM82275.1 - 6.5e-06 26.3 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain AA_permease_2 PF13520.6 EIM82276.1 - 1.6e-31 109.6 44.9 2.8e-31 108.8 45.1 1.3 1 1 0 1 1 1 1 Amino acid permease BRCT_2 PF16589.5 EIM82277.1 - 8e-10 39.0 0.0 9.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIM82277.1 - 9.1e-09 35.6 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EIM82277.1 - 0.0039 17.5 0.0 0.0053 17.0 0.0 1.2 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain SWIRM-assoc_2 PF16496.5 EIM82277.1 - 0.013 14.4 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RTT107_BRCT_5 PF16770.5 EIM82277.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EIM82277.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Asp PF00026.23 EIM82278.1 - 3.3e-42 145.0 0.0 4.7e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM82278.1 - 6.3e-06 26.5 3.5 0.00013 22.2 3.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Peptidase_C14 PF00656.22 EIM82279.1 - 3.9e-20 72.9 0.0 4.6e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EIM82279.1 - 0.0085 16.1 0.1 0.54 10.2 0.0 2.2 2 0 0 2 2 2 2 Raptor N-terminal CASPase like domain CHAT PF12770.7 EIM82279.1 - 0.065 12.6 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 CHAT domain Peptidase_C13 PF01650.18 EIM82279.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Peptidase C13 family Peptidase_C14 PF00656.22 EIM82280.1 - 1.6e-25 90.5 0.0 3.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Caspase domain FAM199X PF15814.5 EIM82281.1 - 3.6 6.5 8.5 5.3 6.0 8.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X Pro-kuma_activ PF09286.11 EIM82282.1 - 2.5e-37 128.3 0.1 2.1e-36 125.4 0.3 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM82282.1 - 9.8e-09 34.9 1.5 9.8e-09 34.9 1.5 2.0 1 1 0 2 2 2 1 Subtilase family EF_TS PF00889.19 EIM82282.1 - 0.065 12.8 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Elongation factor TS BTB PF00651.31 EIM82283.1 - 0.00015 21.9 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Myb_DNA-bind_2 PF08914.11 EIM82284.1 - 4.6e-05 23.5 3.6 0.00026 21.1 3.6 2.3 1 1 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 EIM82284.1 - 0.00013 22.3 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIM82284.1 - 0.0048 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Cnn_1N PF07989.11 EIM82285.1 - 5.5e-24 84.1 10.6 5.5e-24 84.1 10.6 13.4 6 4 7 13 13 13 3 Centrosomin N-terminal motif 1 DUF4201 PF13870.6 EIM82285.1 - 0.0017 18.1 15.4 0.0017 18.1 15.4 10.0 3 3 7 10 10 10 2 Domain of unknown function (DUF4201) MCC-bdg_PDZ PF10506.9 EIM82285.1 - 0.013 15.5 1.3 0.013 15.5 1.3 8.2 9 2 0 9 9 9 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Fez1 PF06818.15 EIM82285.1 - 4.4 7.7 146.4 4.5 7.7 20.9 8.5 1 1 7 8 8 8 0 Fez1 HiaBD2 PF15403.6 EIM82285.1 - 5 7.6 6.3 5.8 7.4 1.4 3.2 3 0 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Myb_DNA-bind_2 PF08914.11 EIM82286.1 - 1.9e-06 28.0 5.2 6.2e-06 26.3 5.2 1.9 1 1 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 EIM82286.1 - 0.00022 21.6 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIM82286.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF4666 PF15697.5 EIM82286.1 - 1.1 9.9 8.8 0.39 11.4 2.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4666) Pkinase_fungal PF17667.1 EIM82287.1 - 4.1e-77 259.7 0.0 8.9e-77 258.6 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EIM82287.1 - 3.8e-06 26.5 0.0 6.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82287.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase ADH_zinc_N PF00107.26 EIM82288.1 - 7.2e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82288.1 - 6.8e-22 79.0 0.0 1.2e-21 78.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82288.1 - 3.8e-12 46.1 0.0 9.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EIM82288.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EIM82289.1 - 2.1e-25 89.2 0.0 3.4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82289.1 - 6.6e-22 79.0 0.0 1.3e-21 78.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82289.1 - 1.7e-10 40.8 0.0 3.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rpn9_C PF18261.1 EIM82289.1 - 0.11 12.1 0.2 0.3 10.7 0.2 1.7 1 0 0 1 1 1 0 Rpn9 C-terminal helix ADH_N_2 PF16884.5 EIM82289.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Cyclase PF04199.13 EIM82290.1 - 1.5e-12 47.9 0.0 3e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Pkinase PF00069.25 EIM82291.1 - 5.4e-46 157.1 0.0 6e-45 153.7 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82291.1 - 3.2e-23 82.4 0.0 1.4e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EIM82291.1 - 0.00081 18.5 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EIM82291.1 - 0.0019 17.1 0.1 0.0029 16.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EIM82291.1 - 0.015 14.9 1.2 0.89 9.1 1.2 2.2 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 EIM82291.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.26 EIM82292.1 - 1.1e-23 83.6 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82292.1 - 2.1e-19 70.9 0.0 3.9e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82292.1 - 1.2e-08 34.8 0.1 3.4e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1768 PF08719.11 EIM82297.1 - 6.7e-18 65.4 0.1 7.5e-18 65.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF2556 PF10831.8 EIM82298.1 - 5.9 6.9 6.9 16 5.5 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2556) MFS_1 PF07690.16 EIM82299.1 - 2.4e-21 76.1 34.9 3.2e-21 75.7 34.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 EIM82300.1 - 4.1e-69 233.5 0.0 5.8e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Shugoshin_C PF07557.11 EIM82302.1 - 1.4e-08 34.4 4.3 1.4e-08 34.4 4.3 3.2 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.11 EIM82302.1 - 1.4e-07 31.2 2.7 2.6e-07 30.4 2.7 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region YL1 PF05764.13 EIM82302.1 - 0.0034 17.6 17.4 0.0034 17.6 17.4 4.2 3 1 1 4 4 4 2 YL1 nuclear protein DUF1768 PF08719.11 EIM82303.1 - 1.9e-31 109.5 0.0 3.9e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) zf-HIT PF04438.16 EIM82303.1 - 0.00018 21.3 12.0 0.052 13.4 1.4 2.4 2 0 0 2 2 2 2 HIT zinc finger YyzF PF14116.6 EIM82303.1 - 0.016 15.2 1.0 1.6 8.8 0.1 2.7 2 0 0 2 2 2 0 YyzF-like protein IL34 PF15036.6 EIM82303.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Lar_restr_allev PF14354.6 EIM82303.1 - 0.19 12.2 8.7 2.1 8.8 0.8 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-CHCC PF10276.9 EIM82303.1 - 0.85 9.7 6.2 15 5.8 0.2 4.2 5 0 0 5 5 5 0 Zinc-finger domain VATC PF18716.1 EIM82303.1 - 5.4 6.9 8.5 0.24 11.3 1.4 2.4 3 0 0 3 3 3 0 Vms1-associating treble clef domain BTB PF00651.31 EIM82304.1 - 3.8e-06 27.1 0.0 5.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain PsaM PF07465.13 EIM82306.1 - 0.22 11.3 2.2 0.44 10.3 2.2 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) RhoGEF PF00621.20 EIM82307.1 - 2.8e-41 141.8 0.9 4.3e-41 141.1 0.9 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 EIM82307.1 - 6.1e-19 67.6 1.3 3.2e-09 36.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EIM82307.1 - 9.6e-17 60.3 0.7 5.7e-08 32.2 0.1 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.7 EIM82307.1 - 6.8e-15 54.9 0.0 1.5e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.17 EIM82307.1 - 2.8e-10 39.7 0.0 0.00064 19.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 EIM82307.1 - 3.2e-10 39.5 1.1 1e-09 37.9 1.1 2.0 1 0 0 1 1 1 1 WH2 motif PH_13 PF16652.5 EIM82307.1 - 7.8e-10 38.8 0.2 7.8e-10 38.8 0.2 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain DUF1720 PF08226.11 EIM82307.1 - 0.0086 16.5 41.5 0.0086 16.5 41.5 5.3 2 2 1 3 3 3 1 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EIM82307.1 - 0.045 13.3 0.1 0.84 9.3 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EIM82307.1 - 0.17 11.9 0.1 25 5.1 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain TolA_bind_tri PF16331.5 EIM82308.1 - 0.037 14.1 3.3 0.046 13.8 0.1 2.4 3 0 0 3 3 3 0 TolA binding protein trimerisation Csm1_N PF18504.1 EIM82308.1 - 3.2 8.2 5.0 6.8 7.1 0.8 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain EphA2_TM PF14575.6 EIM82309.1 - 0.016 16.1 0.0 0.033 15.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2970 PF11174.8 EIM82309.1 - 0.023 14.5 0.7 0.048 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) PTP_tm PF18861.1 EIM82309.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TMEM51 PF15345.6 EIM82309.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 1 1 2 2 2 0 Transmembrane protein 51 TMEM154 PF15102.6 EIM82309.1 - 0.094 12.6 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Plavaka PF18759.1 EIM82310.1 - 1.5e-112 376.1 0.0 2.1e-112 375.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-MYND PF01753.18 EIM82313.1 - 9e-11 41.7 17.7 5.6e-10 39.2 17.7 2.1 1 1 0 1 1 1 1 MYND finger DUF4846 PF16138.5 EIM82313.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (4846) zf-Mss51 PF13824.6 EIM82313.1 - 0.87 9.7 7.3 1.9 8.7 7.3 1.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EIM82313.1 - 3.2 8.1 14.9 0.33 11.3 10.0 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding FtsJ PF01728.19 EIM82314.1 - 5.7e-09 36.3 0.0 1.1e-08 35.4 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 EIM82314.1 - 0.15 10.1 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase MULE PF10551.9 EIM82316.1 - 2.3e-09 37.5 0.0 1.2e-08 35.3 0.0 2.3 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EIM82316.1 - 2.7e-06 26.9 0.1 6.1e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Cys_rich_VLP PF14194.6 EIM82316.1 - 0.071 13.2 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Cysteine-rich VLP FtsJ PF01728.19 EIM82317.1 - 0.0034 17.5 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase FtsJ PF01728.19 EIM82318.1 - 0.0083 16.2 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-MYND PF01753.18 EIM82319.1 - 4.5e-11 42.6 15.2 1.8e-10 40.7 15.2 2.0 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM82319.1 - 0.61 10.4 11.0 1.5 9.2 11.0 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PARP PF00644.20 EIM82320.1 - 2.1e-07 30.8 3.0 1.4e-05 24.7 3.0 3.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain CSTF1_dimer PF16699.5 EIM82320.1 - 0.2 11.4 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain RPAP2_Rtr1 PF04181.13 EIM82320.1 - 0.23 11.8 23.0 0.62 10.4 0.9 5.6 3 1 1 5 5 5 0 Rtr1/RPAP2 family Thrombin_light PF09396.10 EIM82321.1 - 0.0041 16.8 3.8 50 3.8 0.0 4.9 5 0 0 5 5 5 0 Thrombin light chain zf-SCNM1 PF15803.5 EIM82321.1 - 0.0046 16.6 14.4 3.8 7.2 0.0 4.6 4 0 0 4 4 4 3 Zinc-finger of sodium channel modifier 1 YacG PF03884.14 EIM82321.1 - 0.029 14.1 1.2 0.029 14.1 1.2 4.6 5 0 0 5 5 5 0 DNA gyrase inhibitor YacG YyzF PF14116.6 EIM82321.1 - 0.15 12.1 7.7 31 4.7 0.1 5.3 5 0 0 5 5 5 0 YyzF-like protein RPAP2_Rtr1 PF04181.13 EIM82321.1 - 0.2 12.0 16.2 14 6.1 0.2 5.1 5 0 0 5 5 5 0 Rtr1/RPAP2 family GATA PF00320.27 EIM82321.1 - 0.43 10.2 8.4 16 5.2 0.0 4.9 5 0 0 5 5 5 0 GATA zinc finger ADK_lid PF05191.14 EIM82321.1 - 0.72 9.9 13.9 13 5.8 0.0 5.4 5 0 0 5 5 5 0 Adenylate kinase, active site lid zf-HIT PF04438.16 EIM82321.1 - 1.4 8.9 33.6 0.25 11.3 0.5 5.7 5 1 0 5 5 5 0 HIT zinc finger DZR PF12773.7 EIM82321.1 - 1.7 8.8 35.2 25 5.0 9.9 5.4 2 2 0 2 2 1 0 Double zinc ribbon TACI-CRD2 PF09305.10 EIM82321.1 - 2.1 8.4 11.4 51 4.0 0.3 5.1 4 0 0 4 4 4 0 TACI, cysteine-rich domain Endonuclease_7 PF02945.15 EIM82321.1 - 3.2 7.7 18.9 6.2 6.8 0.1 4.8 4 1 0 4 4 4 0 Recombination endonuclease VII zf-MYND PF01753.18 EIM82321.1 - 4.3 7.5 29.7 16 5.7 0.9 6.0 4 3 0 4 4 4 0 MYND finger DUF1768 PF08719.11 EIM82322.1 - 2.7e-27 96.0 0.0 3.1e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.20 EIM82323.1 - 1.6e-07 31.1 6.4 5e-05 23.0 0.2 3.6 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain zf-SCNM1 PF15803.5 EIM82323.1 - 0.59 9.8 9.1 3.7 7.3 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger of sodium channel modifier 1 DUF1768 PF08719.11 EIM82324.1 - 2.2e-26 93.0 0.0 3.2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1202 PF06717.11 EIM82324.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Amidohydro_1 PF01979.20 EIM82324.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family DUF4112 PF13430.6 EIM82325.1 - 8.4e-25 87.1 2.8 1.1e-24 86.7 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Alanine_zipper PF11839.8 EIM82326.1 - 0.007 16.7 0.9 0.007 16.7 0.9 3.3 4 0 0 4 4 4 1 Alanine-zipper, major outer membrane lipoprotein Laminin_I PF06008.14 EIM82326.1 - 0.18 11.5 9.8 0.47 10.1 9.8 1.7 1 1 0 1 1 1 0 Laminin Domain I Rab5-bind PF09311.11 EIM82326.1 - 0.26 10.6 12.4 0.085 12.2 8.1 2.2 2 1 0 2 2 2 0 Rabaptin-like protein DUF5082 PF16888.5 EIM82326.1 - 1.1 9.6 14.4 0.45 10.8 9.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF728 PF05304.12 EIM82326.1 - 1.9 8.3 5.4 0.28 11.0 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF728) TMPIT PF07851.13 EIM82326.1 - 5.5 6.1 6.5 10 5.2 6.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein Fez1 PF06818.15 EIM82326.1 - 5.7 7.3 18.5 0.49 10.8 12.3 1.9 2 0 0 2 2 2 0 Fez1 DUF4407 PF14362.6 EIM82326.1 - 5.9 6.2 8.2 1.6 8.0 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Helicase_C PF00271.31 EIM82327.1 - 2.5e-13 50.3 0.0 4.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 EIM82327.1 - 2.8e-08 33.6 0.8 6.7e-08 32.3 0.8 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal DUF3489 PF11994.8 EIM82327.1 - 0.01 15.9 0.2 0.023 14.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) MRP-S33 PF08293.11 EIM82328.1 - 8.4e-26 90.0 0.2 1e-25 89.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 BTB PF00651.31 EIM82329.1 - 0.0046 17.2 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 EIM82330.1 - 1.9e-36 125.7 47.5 5.9e-35 120.8 47.7 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM82330.1 - 4.3e-06 25.9 8.9 4.3e-06 25.9 8.9 3.9 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 EIM82330.1 - 0.00047 18.7 3.1 0.00047 18.7 3.1 2.6 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Phage_holin_5_1 PF06946.11 EIM82330.1 - 0.081 13.3 0.9 0.36 11.2 0.9 2.1 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 AvrRpt-cleavage PF05627.11 EIM82331.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr DUF778 PF05608.12 EIM82331.1 - 0.24 11.7 2.5 0.33 11.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) CDC73_C PF05179.14 EIM82332.1 - 2.7e-51 173.3 0.2 4.7e-51 172.6 0.2 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EIM82332.1 - 5.4e-05 22.7 0.0 0.017 14.5 0.0 2.4 2 0 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal dsrm PF00035.26 EIM82333.1 - 0.0037 17.9 0.0 0.026 15.2 0.0 2.4 3 0 0 3 3 3 1 Double-stranded RNA binding motif Zn_ribbon_17 PF17120.5 EIM82334.1 - 6.3e-05 22.5 3.5 6.3e-05 22.5 3.5 2.8 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EIM82334.1 - 0.026 14.6 4.6 0.08 13.1 4.6 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger WD40 PF00400.32 EIM82334.1 - 0.39 11.7 18.9 3.4 8.7 2.4 6.3 6 1 0 6 6 6 0 WD domain, G-beta repeat zf-ANAPC11 PF12861.7 EIM82334.1 - 0.66 10.1 5.9 1.8 8.7 5.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EIM82334.1 - 7.9 6.9 11.0 0.098 13.0 2.7 2.2 2 0 0 2 2 2 0 Ring finger domain B12D PF06522.11 EIM82336.1 - 0.013 15.3 1.0 0.031 14.1 1.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Corona_M PF01635.18 EIM82336.1 - 0.091 12.1 2.4 0.11 11.8 2.4 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein F-box-like PF12937.7 EIM82338.1 - 1.7e-09 37.4 0.7 3.5e-08 33.2 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM82338.1 - 2.4 8.1 9.1 10 6.1 0.5 3.9 3 0 0 3 3 3 0 F-box domain OPA3 PF07047.12 EIM82339.1 - 1.8e-45 153.8 0.1 2.7e-45 153.2 0.1 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Tropomyosin PF00261.20 EIM82339.1 - 0.0048 16.3 3.0 0.0048 16.3 3.0 1.4 2 0 0 2 2 2 1 Tropomyosin Rx_N PF18052.1 EIM82339.1 - 0.042 14.1 0.6 0.079 13.2 0.6 1.4 1 0 0 1 1 1 0 Rx N-terminal domain MAP17 PF15807.5 EIM82339.1 - 0.12 12.6 0.9 0.43 10.8 0.2 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SOAR PF16533.5 EIM82339.1 - 0.12 12.3 1.5 0.28 11.2 1.5 1.6 1 0 0 1 1 1 0 STIM1 Orai1-activating region eIF3_N PF09440.10 EIM82339.1 - 0.14 12.6 0.2 0.22 12.0 0.2 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF3496 PF12001.8 EIM82339.1 - 0.34 11.3 3.6 7 7.1 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Zn_clus PF00172.18 EIM82340.1 - 9e-07 28.9 11.1 1.4e-06 28.3 11.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_5_C PF18564.1 EIM82341.1 - 1e-09 38.8 0.3 1.8e-08 34.8 0.0 2.6 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EIM82341.1 - 1.5e-09 37.7 0.0 1.2e-07 31.5 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DAHP_snth_FXD PF18152.1 EIM82342.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain F-box-like PF12937.7 EIM82345.1 - 5.6e-12 45.4 0.1 1.9e-11 43.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM82347.1 - 1.8e-11 43.8 0.9 4e-11 42.6 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82347.1 - 5.7e-07 29.2 0.9 1.4e-06 28.0 0.9 1.8 1 0 0 1 1 1 1 F-box domain Glyco_hydro81C PF17652.1 EIM82347.1 - 0.021 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 C-terminal domain F-box-like PF12937.7 EIM82348.1 - 8.2e-10 38.4 0.4 2.5e-09 36.9 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82348.1 - 0.052 13.4 2.1 0.36 10.8 2.1 2.4 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 EIM82348.1 - 0.9 10.1 5.5 20 5.8 0.2 3.8 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) eIF2A PF08662.11 EIM82349.1 - 8.5e-77 257.4 0.0 1.1e-75 253.8 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EIM82349.1 - 0.016 16.1 0.1 1.1 10.2 0.1 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat PD40 PF07676.12 EIM82349.1 - 0.62 10.1 2.5 44 4.2 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat APH PF01636.23 EIM82350.1 - 9.1e-10 38.9 1.0 3.4e-08 33.7 0.8 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family F-box-like PF12937.7 EIM82351.1 - 2.7e-10 39.9 0.2 3.9e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82351.1 - 0.035 14.0 4.8 0.21 11.5 4.8 2.1 1 1 0 1 1 1 0 F-box domain APH PF01636.23 EIM82352.1 - 2.9e-12 47.0 2.3 8.2e-11 42.3 2.3 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family ADH_zinc_N PF00107.26 EIM82354.1 - 1.6e-25 89.6 1.1 4.9e-25 88.0 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82354.1 - 9e-21 75.3 0.0 3e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82354.1 - 1e-10 41.5 0.1 3.8e-09 36.4 0.0 2.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Strep_his_triad PF04270.13 EIM82354.1 - 0.042 13.9 0.1 1.4 8.9 0.0 2.8 2 0 0 2 2 2 0 Streptococcal histidine triad protein ADH_N_2 PF16884.5 EIM82354.1 - 0.044 13.7 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EIM82355.1 - 2.5e-23 82.5 0.6 4.8e-23 81.6 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82355.1 - 1.4e-17 65.0 0.0 2.9e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82355.1 - 2e-12 46.9 0.1 1.4e-10 41.0 0.0 3.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EIM82355.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Cpn10 PF00166.21 EIM82355.1 - 0.15 12.1 0.3 1.5 8.9 0.1 2.4 2 1 0 2 2 2 0 Chaperonin 10 Kd subunit F-box-like PF12937.7 EIM82357.1 - 1.3e-08 34.5 0.8 4e-08 33.0 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM82357.1 - 0.064 13.2 3.2 1.9 8.5 3.2 2.9 1 1 0 1 1 1 0 F-box domain Pkinase PF00069.25 EIM82358.1 - 9.5e-33 113.7 0.0 1.2e-31 110.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82358.1 - 1.9e-11 43.8 0.0 2.7e-10 40.0 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM82358.1 - 0.088 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EIM82358.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIF_alpha PF05793.12 EIM82358.1 - 0.56 8.7 8.7 1.1 7.8 8.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CCDC53 PF10152.9 EIM82358.1 - 1.4 9.3 4.2 0.52 10.7 0.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Glyco_hydro_31 PF01055.26 EIM82359.1 - 1.2e-148 496.0 1.3 1.5e-148 495.7 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EIM82359.1 - 5.9e-37 126.4 0.2 1e-36 125.6 0.2 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EIM82359.1 - 9.3e-14 51.5 0.6 2.7e-13 50.0 0.6 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Mak10 PF04112.13 EIM82360.1 - 1.9e-47 160.9 0.0 3e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Serglycin PF04360.12 EIM82360.1 - 4.7 7.2 6.8 28 4.6 7.8 1.7 2 0 0 2 2 2 0 Serglycin tRNA-synt_1b PF00579.25 EIM82361.1 - 4.3e-74 249.5 0.0 5.2e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ADH_zinc_N PF00107.26 EIM82362.1 - 5e-28 97.7 0.0 7.5e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82362.1 - 1.1e-21 78.3 0.0 2.1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82362.1 - 9.5e-12 44.8 0.1 2.5e-11 43.4 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Phage_Mu_Gam PF07352.12 EIM82362.1 - 0.076 12.9 0.1 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ADH_zinc_N PF00107.26 EIM82363.1 - 2e-27 95.7 0.6 7.9e-27 93.8 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM82363.1 - 4e-21 76.4 0.0 1e-20 75.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM82363.1 - 1.4e-10 41.0 0.1 6.8e-09 35.6 0.0 2.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EIM82363.1 - 0.0035 17.2 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase MgtE PF01769.16 EIM82364.1 - 9.5e-40 135.8 17.7 2e-20 73.4 0.0 3.2 2 1 1 3 3 3 2 Divalent cation transporter Phage_holin_3_3 PF16083.5 EIM82364.1 - 0.023 14.8 1.3 0.023 14.8 1.3 3.5 5 0 0 5 5 5 0 LydA holin phage, holin superfamily III Ada3 PF10198.9 EIM82365.1 - 8e-24 84.3 0.0 8e-24 84.3 0.0 2.3 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 HAUS-augmin3 PF14932.6 EIM82365.1 - 0.15 11.6 1.0 0.31 10.6 1.0 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FliD_N PF02465.18 EIM82365.1 - 0.34 11.6 3.4 4.1 8.2 0.2 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CR6_interact PF10147.9 EIM82365.1 - 5.7 6.6 17.5 0.12 12.1 0.2 3.1 4 0 0 4 4 4 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TCR_zetazeta PF11628.8 EIM82366.1 - 0.032 13.9 0.2 0.074 12.7 0.2 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain DUF3995 PF13160.6 EIM82367.1 - 0.0035 17.7 12.2 0.22 11.9 5.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3995) Form-deh_trans PF09163.11 EIM82367.1 - 4.3 7.2 6.7 2.7 7.8 0.0 3.2 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane RNA_polI_A34 PF08208.11 EIM82368.1 - 2.6e-18 66.9 41.9 3.1e-16 60.1 22.7 4.3 2 1 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 Phos_pyr_kin PF08543.12 EIM82369.1 - 5.8e-78 261.7 0.7 2.3e-56 190.9 0.0 2.3 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EIM82369.1 - 5e-39 134.3 0.1 7.2e-39 133.8 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EIM82369.1 - 3e-08 33.3 0.4 4.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase 2H-phosphodiest PF08975.10 EIM82370.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) DUF5401 PF17380.2 EIM82370.1 - 0.14 10.2 4.9 0.2 9.7 4.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FMO-like PF00743.19 EIM82371.1 - 5.1e-23 81.3 0.0 1.7e-18 66.3 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM82371.1 - 3.3e-20 72.6 0.0 1.1e-17 64.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM82371.1 - 3.1e-15 56.2 0.4 1.5e-10 40.8 0.0 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM82371.1 - 2.1e-10 40.3 0.1 1.1e-07 31.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EIM82371.1 - 8.6e-06 25.9 0.5 0.0089 16.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EIM82371.1 - 7e-05 23.3 1.2 0.096 13.3 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM82371.1 - 0.00076 18.8 0.6 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 EIM82371.1 - 0.0022 18.2 0.2 0.11 12.8 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 EIM82371.1 - 0.0038 16.6 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EIM82371.1 - 0.0056 16.7 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EIM82371.1 - 0.0056 16.9 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM82371.1 - 0.0094 15.2 0.3 0.1 11.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 EIM82371.1 - 0.011 14.5 0.1 0.031 13.0 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF498 PF04430.14 EIM82371.1 - 0.016 15.3 0.1 2.3 8.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) NAD_binding_7 PF13241.6 EIM82371.1 - 0.038 14.4 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EIM82371.1 - 0.044 12.8 0.9 0.79 8.7 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM82371.1 - 0.061 12.4 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 EIM82371.1 - 0.076 12.9 1.8 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EIM82371.1 - 0.32 10.0 0.1 0.32 10.0 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Syntaxin-18_N PF10496.9 EIM82372.1 - 1.1e-15 57.6 0.1 1.1e-15 57.6 0.1 2.6 4 0 0 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EIM82372.1 - 0.0059 16.6 0.6 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 SNARE domain Peptidase_M24_C PF16188.5 EIM82372.1 - 0.21 11.7 0.7 23 5.2 0.1 2.7 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 F-box PF00646.33 EIM82373.1 - 2.2e-05 24.2 2.1 2.2e-05 24.2 2.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM82373.1 - 0.51 10.3 9.5 0.042 13.8 3.5 2.4 3 0 0 3 3 3 0 F-box-like HTH_23 PF13384.6 EIM82373.1 - 7.7 6.4 12.1 8.6 6.3 0.2 4.1 4 0 0 4 4 4 0 Homeodomain-like domain AP3D1 PF06375.11 EIM82376.1 - 0.09 13.0 3.4 0.2 11.9 3.4 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 NST1 PF13945.6 EIM82376.1 - 8.8 6.4 12.9 3.4 7.7 10.5 1.5 1 1 0 2 2 2 0 Salt tolerance down-regulator F-box PF00646.33 EIM82377.1 - 8.1e-08 32.0 0.9 2.5e-07 30.4 0.9 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM82377.1 - 0.00017 21.4 0.6 0.00054 19.8 0.6 1.8 1 0 0 1 1 1 1 F-box-like Ribosomal_L12 PF00542.19 EIM82377.1 - 0.038 14.4 0.5 0.072 13.4 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain bHLH-MYC_N PF14215.6 EIM82381.1 - 0.19 12.0 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal F-box PF00646.33 EIM82383.1 - 2e-11 43.5 5.0 1.1e-05 25.2 0.2 3.0 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 EIM82383.1 - 1.2e-07 31.5 10.1 0.00018 21.4 1.3 3.1 3 0 0 3 3 3 2 F-box-like F-box_4 PF15966.5 EIM82383.1 - 0.00061 19.6 0.2 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 F-box DZR PF12773.7 EIM82383.1 - 0.7 10.0 5.4 19 5.4 1.6 3.3 3 0 0 3 3 3 0 Double zinc ribbon Di19_C PF14571.6 EIM82383.1 - 1.3 9.6 0.0 1.3 9.6 0.0 2.9 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal PP2C PF00481.21 EIM82384.1 - 5.5e-25 88.5 0.0 4.9e-20 72.3 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EIM82384.1 - 6e-08 32.6 0.0 1.3e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EIM82384.1 - 0.00077 19.4 0.1 0.12 12.3 0.0 2.7 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Methyltransf_25 PF13649.6 EIM82385.1 - 2.2e-10 41.1 0.0 5.6e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM82385.1 - 1.3e-09 38.6 0.0 2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM82385.1 - 3.4e-08 33.5 0.0 4.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM82385.1 - 8.2e-08 32.9 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM82385.1 - 1.2e-07 31.7 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM82385.1 - 3.9e-05 23.1 0.0 0.0001 21.7 0.0 1.6 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EIM82385.1 - 0.0085 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 EIM82385.1 - 0.01 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) WHH PF14414.6 EIM82385.1 - 0.085 12.7 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH IMS PF00817.20 EIM82386.1 - 5.1e-41 140.2 0.0 9.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EIM82386.1 - 1.1e-22 80.2 2.5 1.1e-22 80.2 2.5 1.8 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EIM82386.1 - 3.1e-15 56.9 0.0 1.3e-14 54.9 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EIM82386.1 - 1.3e-07 31.9 0.0 2.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EIM82386.1 - 0.00014 21.7 0.1 0.00028 20.7 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EIM82386.1 - 0.00084 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 EIM82386.1 - 0.0014 18.9 0.0 0.0044 17.3 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.11 EIM82386.1 - 0.0029 17.9 0.7 0.018 15.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1805) UBM PF14377.6 EIM82386.1 - 0.23 11.0 6.9 9.4 5.8 0.2 3.8 3 0 0 3 3 3 0 Ubiquitin binding region IMS PF00817.20 EIM82388.1 - 2.2e-10 40.7 0.0 4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DUF1805 PF08827.11 EIM82388.1 - 0.015 15.6 0.1 0.036 14.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Ccdc124 PF06244.12 EIM82390.1 - 2.3e-29 102.6 0.3 2.3e-29 102.6 0.3 1.9 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Glycos_transf_1 PF00534.20 EIM82392.1 - 4.3e-22 78.5 0.0 8.6e-21 74.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EIM82392.1 - 2.3e-17 63.5 0.2 3.1e-16 59.8 0.2 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EIM82392.1 - 2.4e-09 37.8 0.5 7.1e-09 36.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EIM82392.1 - 8e-08 32.8 0.0 5.1e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EIM82392.1 - 0.003 17.9 0.0 0.0059 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 CHAT PF12770.7 EIM82393.1 - 1.1e-32 113.7 0.2 1.7e-32 113.0 0.2 1.2 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM82393.1 - 4.6 7.3 11.4 53 3.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_S10 PF00450.22 EIM82394.1 - 8.1e-99 331.8 8.7 1e-98 331.6 8.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GTP_CH_N PF12471.8 EIM82394.1 - 0.0093 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal F-box-like PF12937.7 EIM82395.1 - 1.2e-08 34.7 1.9 1.5e-07 31.2 1.1 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM82395.1 - 8.9e-08 31.8 0.7 8.9e-08 31.8 0.7 2.3 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 EIM82395.1 - 0.0048 16.8 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 F-box Trypan_PARP PF05887.11 EIM82396.1 - 0.66 10.0 6.2 1.2 9.1 6.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pribosyltran_N PF13793.6 EIM82397.1 - 7e-51 171.0 0.4 3.9e-49 165.4 0.1 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EIM82397.1 - 2.1e-36 125.7 1.1 1.5e-31 109.8 0.7 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EIM82397.1 - 2.5e-18 66.1 0.4 1e-15 57.6 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 EIM82397.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PS_pyruv_trans PF04230.13 EIM82397.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Pkinase PF00069.25 EIM82398.1 - 2.3e-65 220.6 0.0 2.9e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82398.1 - 2.1e-44 151.8 0.0 2.8e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM82398.1 - 0.00026 19.9 0.0 0.00042 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EIM82398.1 - 0.041 12.8 0.1 0.087 11.8 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 EIM82398.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like F-box PF00646.33 EIM82399.1 - 1.1e-07 31.6 2.3 1.4e-07 31.2 0.6 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM82399.1 - 9e-06 25.5 0.3 3.1e-05 23.8 0.3 1.9 1 0 0 1 1 1 1 F-box-like HypA PF01155.19 EIM82400.1 - 0.29 11.2 1.4 6.6 6.8 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Spc7 PF08317.11 EIM82401.1 - 4.2e-05 22.6 5.5 6.4e-05 22.0 5.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 EIM82401.1 - 0.0076 14.9 10.8 0.01 14.5 10.8 1.1 1 0 0 1 1 1 1 AAA domain Laminin_II PF06009.12 EIM82401.1 - 0.036 14.1 6.3 0.26 11.3 0.9 2.5 2 0 0 2 2 2 0 Laminin Domain II IFT57 PF10498.9 EIM82401.1 - 0.16 10.9 6.5 0.027 13.4 2.0 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF812 PF05667.11 EIM82401.1 - 0.43 9.4 9.8 0.61 8.9 9.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) COG2 PF06148.11 EIM82401.1 - 0.51 10.4 7.7 0.075 13.1 2.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EIM82401.1 - 0.52 10.3 4.6 0.83 9.7 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 EIM82401.1 - 0.73 10.5 10.4 0.57 10.8 6.5 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med9 PF07544.13 EIM82401.1 - 1.7 8.8 7.2 1.1 9.4 2.3 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 KxDL PF10241.9 EIM82401.1 - 2.8 8.3 8.6 8.3 6.8 0.4 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein ZapB PF06005.12 EIM82401.1 - 3.2 8.3 11.8 7 7.2 5.4 2.7 2 0 0 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 EIM82401.1 - 3.5 7.7 11.7 2.2 8.4 2.7 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 EIM82401.1 - 9.7 5.2 11.7 18 4.3 4.0 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Calcipressin PF04847.12 EIM82402.1 - 4.6e-37 127.6 0.0 6.9e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 EIM82402.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.6 EIM82402.1 - 0.22 11.4 0.0 14 5.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) Pyr_redox_3 PF13738.6 EIM82403.1 - 1.3e-19 70.6 0.0 3.6e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIM82403.1 - 3.8e-16 58.6 0.0 1.4e-14 53.5 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM82403.1 - 2.3e-12 46.7 0.0 5.8e-09 35.6 0.0 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM82403.1 - 6.4e-11 42.0 0.1 2.4e-09 36.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EIM82403.1 - 5e-06 26.6 0.0 0.00029 21.0 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIM82403.1 - 5.4e-05 22.1 0.4 0.00035 19.4 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 EIM82403.1 - 7.6e-05 22.8 0.2 0.11 12.5 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EIM82403.1 - 0.00016 21.0 0.1 0.0004 19.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EIM82403.1 - 0.00068 20.2 1.9 0.12 12.9 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM82403.1 - 0.0012 18.0 0.2 0.0034 16.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EIM82403.1 - 0.02 14.2 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4147 PF13660.6 EIM82403.1 - 0.05 13.1 0.0 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Lycopene_cycl PF05834.12 EIM82403.1 - 0.065 12.3 0.3 0.27 10.2 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 EIM82403.1 - 0.23 10.5 0.1 1 8.4 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A ENTH PF01417.20 EIM82405.1 - 9.8e-41 138.7 0.0 1.5e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EIM82405.1 - 8.4e-10 38.1 0.2 1.4e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 ANTH domain DPBB_1 PF03330.18 EIM82407.1 - 2.4e-07 30.9 0.1 3.5e-07 30.4 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase F-box-like PF12937.7 EIM82408.1 - 1.5e-06 27.9 0.4 6.5e-06 25.9 0.4 2.2 1 1 0 1 1 1 1 F-box-like EGF_2 PF07974.13 EIM82409.1 - 0.00077 19.8 14.1 0.00077 19.8 14.1 12.6 9 3 0 9 9 9 2 EGF-like domain GF_recep_IV PF14843.6 EIM82409.1 - 0.006 16.4 17.7 0.006 16.4 17.7 6.3 1 1 5 6 6 6 3 Growth factor receptor domain IV Laminin_EGF PF00053.24 EIM82409.1 - 0.0089 16.2 19.1 0.0089 16.2 19.1 9.5 1 1 4 5 5 5 1 Laminin EGF domain DUF4381 PF14316.6 EIM82409.1 - 0.014 15.6 0.9 0.025 14.8 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3382 PF11862.8 EIM82409.1 - 0.17 12.2 0.3 0.31 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) LapA_dom PF06305.11 EIM82409.1 - 0.26 11.1 1.0 0.54 10.1 1.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain VSP PF03302.13 EIM82409.1 - 2.7 6.8 168.7 0.073 11.9 25.7 7.0 2 1 5 7 7 7 0 Giardia variant-specific surface protein F-box-like PF12937.7 EIM82410.1 - 6.1e-07 29.2 0.8 2.3e-06 27.4 0.8 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82410.1 - 1.2e-06 28.2 0.9 1.2e-06 28.2 0.9 2.4 2 0 0 2 2 2 1 F-box domain Pro-kuma_activ PF09286.11 EIM82411.1 - 3.2e-36 124.7 0.1 7.5e-36 123.5 0.2 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Hist_deacetyl PF00850.19 EIM82412.1 - 5.8e-81 272.3 0.0 7.4e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Per1 PF04080.13 EIM82413.1 - 2.1e-98 329.2 13.6 2.5e-98 328.9 13.6 1.1 1 0 0 1 1 1 1 Per1-like family Glyco_hydro_12 PF01670.16 EIM82414.1 - 1.2e-38 133.3 9.4 1.4e-38 133.1 9.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 UvrD_C_2 PF13538.6 EIM82415.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain rhaM PF05336.13 EIM82415.1 - 0.033 14.3 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 L-rhamnose mutarotase Viral_helicase1 PF01443.18 EIM82415.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IQ PF00612.27 EIM82416.1 - 0.1 12.5 1.4 0.1 12.5 1.4 2.0 3 0 0 3 3 3 0 IQ calmodulin-binding motif Peroxidase_2 PF01328.17 EIM82419.1 - 3.2e-52 177.8 0.1 4e-52 177.5 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 AA_kinase PF00696.28 EIM82421.1 - 2.5e-40 138.6 1.2 3.7e-40 138.0 1.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EIM82421.1 - 1e-06 28.6 5.0 0.0062 16.5 0.2 3.3 3 1 0 3 3 3 2 PUA domain Pkinase PF00069.25 EIM82424.1 - 8.6e-27 94.1 0.0 1.4e-26 93.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82424.1 - 4e-12 46.0 0.0 5.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM82424.1 - 1.4e-05 25.2 0.5 3.3e-05 23.9 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM82424.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EIM82424.1 - 0.015 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EIM82424.1 - 0.034 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM82424.1 - 0.049 13.0 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 EIM82424.1 - 0.052 12.6 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1691 PF07950.11 EIM82425.1 - 0.0041 17.8 1.7 0.012 16.3 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1691) E1-E2_ATPase PF00122.20 EIM82426.1 - 1.5e-47 161.5 1.5 3.5e-47 160.3 1.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EIM82426.1 - 6e-22 78.2 4.8 1.3e-17 64.1 1.5 3.7 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EIM82426.1 - 9.4e-20 71.8 0.0 6.1e-18 65.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIM82426.1 - 1.5e-17 63.4 0.0 4.5e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EIM82426.1 - 5e-11 42.1 0.0 1.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIM82426.1 - 0.00028 20.7 0.4 0.033 13.9 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 EIM82429.1 - 8.3e-29 100.4 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM82429.1 - 6.8e-14 52.0 0.0 9.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM82429.1 - 1.6e-08 34.6 0.0 2.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EIM82429.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 EIM82429.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 EIM82429.1 - 0.025 14.1 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Colicin_V PF02674.16 EIM82430.1 - 0.0013 18.7 4.6 0.0029 17.6 4.6 1.6 1 0 0 1 1 1 1 Colicin V production protein Phage_holin_3_6 PF07332.11 EIM82430.1 - 0.78 9.8 4.3 2.3 8.3 4.3 1.9 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Colicin_V PF02674.16 EIM82431.1 - 0.00023 21.2 4.7 0.00038 20.5 4.7 1.4 1 0 0 1 1 1 1 Colicin V production protein adh_short PF00106.25 EIM82432.1 - 1.1e-27 96.8 0.0 1.5e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM82432.1 - 2e-13 50.5 0.0 2.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM82432.1 - 2.1e-08 34.3 0.2 3.5e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 EIM82432.1 - 0.0017 18.2 0.5 0.0031 17.4 0.5 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 EIM82432.1 - 0.027 13.8 0.0 0.076 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EIM82432.1 - 0.035 13.6 0.0 0.088 12.3 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 EIM82432.1 - 0.045 13.6 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 EIM82432.1 - 0.086 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EIM82432.1 - 0.12 12.3 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Helicase_RecD PF05127.14 EIM82432.1 - 0.15 11.9 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Helicase Ank_4 PF13637.6 EIM82434.1 - 1.2e-11 44.9 0.3 1.1e-05 25.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM82434.1 - 4.3e-09 36.8 0.1 7.7e-09 36.0 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIM82434.1 - 2.6e-08 33.9 2.3 0.0017 18.7 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EIM82434.1 - 3.8e-08 33.0 0.2 0.002 18.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EIM82434.1 - 3.4e-06 27.2 0.0 9.2e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Goodbye PF17109.5 EIM82435.1 - 1.9e-23 83.2 0.1 1.2e-22 80.6 0.0 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EIM82435.1 - 9.6e-13 48.4 0.0 2.9e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EIM82435.1 - 4.2e-07 30.5 0.0 1.6e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM82435.1 - 5.8e-05 23.4 0.1 0.00052 20.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EIM82435.1 - 0.00064 20.2 0.0 0.0065 16.9 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EIM82435.1 - 0.0016 18.8 0.3 0.04 14.3 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_17 PF13207.6 EIM82435.1 - 0.036 14.5 0.0 0.17 12.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIM82435.1 - 0.041 14.4 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EIM82435.1 - 0.082 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.31 EIM82436.1 - 1.1e-15 58.0 0.0 5.9e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM82436.1 - 3.2e-13 49.8 0.0 6.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM82436.1 - 9.6e-05 22.4 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Host_attach PF10116.9 EIM82436.1 - 0.038 14.6 0.3 0.18 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein required for attachment to host cells SWI2_SNF2 PF18766.1 EIM82436.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Radial_spoke_3 PF06098.11 EIM82437.1 - 0.79 8.9 16.8 1.4 8.2 16.8 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 CDC45 PF02724.14 EIM82437.1 - 1.4 7.1 10.3 1.6 6.9 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF883 PF05957.13 EIM82437.1 - 3.8 8.2 13.5 8.1 7.1 13.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DDRGK PF09756.9 EIM82437.1 - 4.8 6.7 27.9 8.4 5.9 27.9 1.4 1 0 0 1 1 1 0 DDRGK domain Piwi PF02171.17 EIM82439.1 - 1.4e-66 224.8 0.0 1.9e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EIM82439.1 - 1.1e-10 41.0 0.0 4.8e-10 38.9 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 EIM82439.1 - 4.1e-10 39.8 0.0 1.6e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 EIM82439.1 - 8.2e-10 39.4 0.0 2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EIM82439.1 - 1.7e-06 28.2 0.0 8.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain Cas_CT1975 PF09344.10 EIM82439.1 - 0.004 16.7 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 CT1975-like protein Piwi PF02171.17 EIM82440.1 - 3.9e-74 249.6 0.0 5.8e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EIM82440.1 - 1.6e-14 53.3 0.0 7.3e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoN PF16486.5 EIM82440.1 - 3.4e-14 53.6 0.0 7.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EIM82440.1 - 1.3e-07 31.8 0.1 5.1e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 EIM82440.1 - 5.4e-06 26.6 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Cerato-platanin PF07249.12 EIM82441.1 - 8.4e-47 158.2 1.2 9.7e-47 158.0 1.2 1.0 1 0 0 1 1 1 1 Cerato-platanin HMG_box PF00505.19 EIM82442.1 - 9.2e-11 42.0 0.9 1.7e-10 41.2 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM82442.1 - 4.8e-05 23.9 0.4 7.8e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 HMG-box domain Glyoxalase_3 PF13468.6 EIM82444.1 - 4.6e-29 101.8 0.0 1e-27 97.4 0.0 2.1 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EIM82444.1 - 0.00011 22.5 0.0 0.0033 17.7 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EIM82444.1 - 0.036 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Pkinase PF00069.25 EIM82446.1 - 1.6e-43 149.0 0.0 1.6e-36 126.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82446.1 - 3.7e-25 88.7 0.0 7.5e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM82446.1 - 0.00061 19.2 0.0 0.028 13.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIM82446.1 - 0.0007 19.0 0.4 0.0012 18.3 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM82446.1 - 0.0019 18.1 0.8 0.44 10.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF5321 PF17254.2 EIM82447.1 - 5.4 6.4 5.0 7.9 5.9 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5321) Peptidase_C14 PF00656.22 EIM82449.1 - 1.9e-21 77.1 0.0 2.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM82449.1 - 0.0018 17.8 0.0 0.0064 15.9 0.0 1.8 2 0 0 2 2 2 1 CHAT domain ABC2_membrane PF01061.24 EIM82450.1 - 3.4e-37 127.9 19.0 3.4e-37 127.9 19.0 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EIM82450.1 - 2.6e-24 86.3 0.0 4.2e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EIM82450.1 - 0.0042 16.2 23.9 0.0078 15.4 23.4 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_18 PF13238.6 EIM82450.1 - 0.0043 17.6 0.0 0.0075 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EIM82450.1 - 0.0089 15.9 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system PCSK9_C3 PF18463.1 EIM82450.1 - 0.02 15.1 7.1 0.056 13.7 7.1 1.7 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain AAA_16 PF13191.6 EIM82450.1 - 0.042 14.2 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EIM82450.1 - 0.043 13.7 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EIM82450.1 - 0.055 13.4 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EIM82450.1 - 0.075 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIM82450.1 - 0.079 12.7 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vert_HS_TF PF06546.11 EIM82450.1 - 0.083 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor NACHT PF05729.12 EIM82450.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Saf_2TM PF18303.1 EIM82450.1 - 0.21 11.1 1.2 5.4 6.6 0.2 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain AAA_28 PF13521.6 EIM82450.1 - 0.25 11.6 0.3 0.43 10.8 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EIM82450.1 - 0.3 10.8 1.1 1.5 8.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain Laminin_EGF PF00053.24 EIM82450.1 - 1.8 8.8 21.9 0.19 11.9 2.5 3.5 3 0 0 3 3 3 0 Laminin EGF domain SOBP PF15279.6 EIM82451.1 - 2.6 8.6 13.2 3.3 8.2 13.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DPBB_1 PF03330.18 EIM82452.1 - 9.8e-07 29.0 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase COX17 PF05051.13 EIM82453.1 - 1.3e-21 76.7 6.1 1.5e-21 76.4 6.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF5332 PF17266.2 EIM82453.1 - 0.027 14.2 2.8 0.03 14.0 2.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5332) UPF0203 PF05254.12 EIM82453.1 - 0.052 13.8 3.8 0.098 12.9 3.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DPBB_1 PF03330.18 EIM82454.1 - 1.9e-07 31.2 0.1 2.9e-07 30.7 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase F-box-like PF12937.7 EIM82455.1 - 5.1e-08 32.7 0.1 1.7e-07 31.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82455.1 - 0.043 13.7 3.7 0.063 13.2 0.0 2.9 4 0 0 4 4 4 0 F-box domain MscS_porin PF12795.7 EIM82456.1 - 0.013 15.1 7.9 0.019 14.5 7.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Fez1 PF06818.15 EIM82456.1 - 0.047 14.2 8.6 0.068 13.6 8.6 1.1 1 0 0 1 1 1 0 Fez1 Golgin_A5 PF09787.9 EIM82456.1 - 0.061 12.8 9.0 0.14 11.5 9.0 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 EMP24_GP25L PF01105.24 EIM82456.1 - 0.066 13.1 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Atg14 PF10186.9 EIM82456.1 - 0.067 12.3 3.2 0.1 11.7 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EIM82456.1 - 0.35 10.2 3.4 0.46 9.8 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 EIM82456.1 - 0.51 10.4 11.4 0.77 9.8 11.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.9 EIM82456.1 - 0.9 8.0 4.6 1.2 7.6 4.6 1.1 1 0 0 1 1 1 0 Macoilin family GAS PF13851.6 EIM82456.1 - 1.9 7.8 9.4 27 4.0 11.0 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 EIM82456.1 - 1.9 8.7 9.9 5.4 7.2 10.0 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 EIM82456.1 - 2.3 7.4 9.3 0.3 10.3 4.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ABC_tran_CTD PF16326.5 EIM82456.1 - 5.8 7.2 6.7 2.2 8.6 2.2 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain DDOST_48kD PF03345.14 EIM82457.1 - 8.3e-128 426.8 0.0 9.5e-128 426.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DASH_Spc34 PF08657.10 EIM82458.1 - 0.051 13.4 3.0 0.085 12.6 3.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 IFT20 PF14931.6 EIM82458.1 - 0.1 12.8 4.3 0.18 12.0 4.3 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 HOOK PF05622.12 EIM82458.1 - 0.16 10.1 8.5 0.22 9.7 8.5 1.1 1 0 0 1 1 1 0 HOOK protein DUF724 PF05266.14 EIM82458.1 - 0.84 9.4 7.9 1.3 8.8 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FUSC PF04632.12 EIM82458.1 - 1 7.8 5.2 1.5 7.2 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 EIM82458.1 - 1.1 9.9 9.5 0.86 10.3 5.1 2.5 1 1 1 2 2 2 0 SlyX PRKG1_interact PF15898.5 EIM82458.1 - 1.1 10.1 10.0 0.8 10.6 7.8 1.8 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 EIM82458.1 - 3.1 8.3 14.9 13 6.3 14.9 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region F-box-like PF12937.7 EIM82460.1 - 0.0033 17.3 0.0 0.0033 17.3 0.0 3.1 4 1 0 4 4 4 1 F-box-like ADK PF00406.22 EIM82461.1 - 1.4e-59 200.6 0.0 1.7e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EIM82461.1 - 9.7e-22 77.9 0.3 1.9e-21 76.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EIM82461.1 - 1.7e-16 59.9 0.0 3.3e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EIM82461.1 - 0.00019 21.6 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM82461.1 - 0.0054 17.3 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PI3K_P85_iSH2 PF16454.5 EIM82461.1 - 0.028 14.0 0.3 1.4 8.4 0.0 3.0 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain IstB_IS21 PF01695.17 EIM82461.1 - 0.16 11.7 0.0 0.63 9.8 0.0 2.0 3 0 0 3 3 3 0 IstB-like ATP binding protein F-box-like PF12937.7 EIM82462.1 - 1.1e-06 28.4 0.4 9.8e-06 25.4 0.4 2.6 1 1 0 1 1 1 1 F-box-like HIM1 PF08732.10 EIM82462.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 HIM1 Pro_CA PF00484.19 EIM82464.1 - 3.9e-36 124.7 0.1 1.9e-34 119.2 0.1 2.1 1 1 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 EIM82465.1 - 1.8e-37 129.1 0.1 1.1e-35 123.2 0.1 2.1 1 1 0 1 1 1 1 Carbonic anhydrase DEAD PF00270.29 EIM82467.1 - 1.1e-21 77.4 0.0 1.9e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EIM82467.1 - 1.2e-16 61.2 0.6 4.8e-16 59.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EIM82467.1 - 4.2e-13 49.6 0.7 2e-10 41.0 0.1 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain CDT1 PF08839.11 EIM82467.1 - 7.2e-07 29.7 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 EIM82467.1 - 3.9e-06 27.0 0.2 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 EIM82468.1 - 5.7e-23 81.6 0.0 8.7e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82468.1 - 7.7e-15 54.9 0.0 1.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-bind_2 PF08914.11 EIM82470.1 - 2e-06 27.9 5.2 0.026 14.7 0.8 2.6 2 0 0 2 2 2 2 Rap1 Myb domain Myb_DNA-binding PF00249.31 EIM82470.1 - 0.12 12.6 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain ADH_N PF08240.12 EIM82471.1 - 1.6e-30 105.2 3.7 3.2e-30 104.2 3.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM82471.1 - 1.1e-17 64.2 0.0 2.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM82471.1 - 4.3e-10 39.4 0.0 6.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIM82471.1 - 3.6e-07 31.3 0.0 6.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EIM82471.1 - 0.00088 18.6 0.3 0.0013 18.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_3 PF03447.16 EIM82471.1 - 0.0016 19.0 0.0 0.0034 18.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 EIM82471.1 - 0.0054 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase SPT16 PF08644.11 EIM82472.1 - 1.2e-56 191.1 0.6 1.2e-56 191.1 0.6 2.5 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EIM82472.1 - 3.3e-41 140.8 0.0 1.2e-40 138.9 0.0 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EIM82472.1 - 7.8e-25 87.8 0.0 1.4e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EIM82472.1 - 6.5e-15 55.3 0.0 2e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 EIM82472.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Metallophos PF00149.28 EIM82473.1 - 1.3e-12 48.7 0.0 2.1e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM82473.1 - 1e-08 35.6 0.3 2.3e-07 31.1 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Apt1 PF10351.9 EIM82474.1 - 6.5 5.5 7.7 0.23 10.3 2.1 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4419 PF14388.6 EIM82475.1 - 3.4e-111 371.5 0.0 4e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF1314 PF07013.11 EIM82475.1 - 0.085 12.7 0.0 0.22 11.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1314) His_Phos_2 PF00328.22 EIM82476.1 - 3.1e-47 161.8 0.0 3.7e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HTH_9 PF08221.11 EIM82477.1 - 5.3e-20 71.3 2.0 3.5e-14 52.6 0.2 3.8 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 EIM82477.1 - 6.7e-19 68.6 3.9 5e-16 59.2 3.1 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 EIM82477.1 - 4e-09 36.3 0.0 1.6e-07 31.2 0.1 3.3 3 0 0 3 3 3 1 TFIIE alpha subunit Tubulin PF00091.25 EIM82478.1 - 3.1e-70 236.4 0.0 7.4e-70 235.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIM82478.1 - 3.9e-46 156.3 0.5 7.5e-46 155.4 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EIM82478.1 - 0.00027 20.7 0.0 0.00076 19.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 EIM82478.1 - 0.0005 20.4 0.0 0.002 18.4 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Hrs_helical PF12210.8 EIM82478.1 - 0.038 14.5 0.4 0.089 13.3 0.4 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CRCB PF02537.15 EIM82479.1 - 4.9 7.5 7.1 8.5 6.8 6.7 1.7 1 1 1 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) PHtD_u1 PF16645.5 EIM82480.1 - 0.057 13.8 3.1 0.12 12.8 3.1 1.5 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein CENP-X PF09415.10 EIM82481.1 - 0.14 12.5 0.8 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 CENP-S associating Centromere protein X 5_nucleotid_C PF02872.18 EIM82482.1 - 2.4e-25 89.6 0.0 4.5e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EIM82482.1 - 4.8e-08 33.8 0.4 1.1e-07 32.6 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF4820 PF16091.5 EIM82482.1 - 0.31 10.4 2.1 0.51 9.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2420 PF10336.9 EIM82483.1 - 4.9e-08 33.0 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) MccV PF17508.2 EIM82484.1 - 0.06 13.9 1.0 0.12 12.9 0.2 1.9 2 0 0 2 2 2 0 Microcin V bacteriocin BCS1_N PF08740.11 EIM82485.1 - 2.5e-31 109.1 3.7 4e-31 108.5 3.7 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EIM82485.1 - 8.5e-18 65.1 0.0 5.4e-17 62.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM82485.1 - 0.00082 19.8 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EIM82485.1 - 0.0024 17.7 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EIM82485.1 - 0.0049 16.7 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EIM82485.1 - 0.029 14.4 0.1 0.1 12.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EIM82485.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EIM82485.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EIM82485.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EIM82485.1 - 0.17 11.2 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 KaiC HTH_Tnp_Tc5 PF03221.16 EIM82485.1 - 0.22 11.6 1.1 0.72 9.9 0.0 2.3 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain COX14 PF14880.6 EIM82486.1 - 1.5 8.7 5.5 0.33 10.8 0.5 2.4 3 0 0 3 3 3 0 Cytochrome oxidase c assembly MBF1 PF08523.10 EIM82487.1 - 1.2e-25 89.8 1.8 2.1e-25 89.0 1.8 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EIM82487.1 - 1.8e-13 50.3 0.1 2.8e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EIM82487.1 - 8.6e-05 22.8 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EIM82487.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EIM82487.1 - 0.05 13.5 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain NACHT PF05729.12 EIM82488.1 - 0.0033 17.4 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EIM82488.1 - 0.0045 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RHSP PF07999.11 EIM82488.1 - 0.032 13.0 0.2 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon hot spot protein T2SSE PF00437.20 EIM82488.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EIM82488.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EIM82488.1 - 0.13 12.6 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EIM82488.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 EIM82488.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EIM82488.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NAD_binding_7 PF13241.6 EIM82489.1 - 2.8e-32 111.3 0.0 7.1e-32 109.9 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EIM82489.1 - 1e-22 79.5 0.3 1.7e-22 78.8 0.3 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EIM82489.1 - 5.4e-15 54.5 0.5 5.4e-15 54.5 0.5 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central ThiF PF00899.21 EIM82489.1 - 0.16 11.3 1.9 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 ThiF family Tetraspanin PF00335.20 EIM82490.1 - 0.005 16.6 19.6 0.011 15.5 19.6 1.6 1 1 0 1 1 1 1 Tetraspanin family Arteri_Gl PF00951.18 EIM82490.1 - 0.02 14.7 0.0 0.02 14.7 0.0 2.5 2 1 1 3 3 3 0 Arterivirus GL envelope glycoprotein IFNGR1 PF07140.11 EIM82490.1 - 0.15 12.2 0.3 4.4 7.4 0.4 2.2 1 1 1 2 2 2 0 Interferon gamma receptor (IFNGR1) DUF4191 PF13829.6 EIM82490.1 - 0.18 11.1 4.1 3.2 7.0 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) Baculo_11_kDa PF06143.11 EIM82490.1 - 0.22 11.1 4.9 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family Bmt2 PF11968.8 EIM82491.1 - 4.2e-59 200.1 0.0 7.1e-59 199.3 0.0 1.4 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EIM82491.1 - 9.4e-05 22.3 0.0 0.00068 19.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FAM199X PF15814.5 EIM82491.1 - 0.02 13.9 3.5 0.03 13.4 3.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X Methyltransf_11 PF08241.12 EIM82491.1 - 0.038 14.6 0.0 0.092 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SprA-related PF12118.8 EIM82491.1 - 0.59 9.2 5.4 0.83 8.7 5.4 1.1 1 0 0 1 1 1 0 SprA-related family F-box-like PF12937.7 EIM82492.1 - 5.4e-05 23.0 0.1 0.0031 17.4 0.1 2.8 2 0 0 2 2 2 2 F-box-like RNA12 PF10443.9 EIM82494.1 - 5.9e-113 377.9 0.0 4.6e-62 210.2 0.1 2.2 1 1 1 2 2 2 2 RNA12 protein AAA_16 PF13191.6 EIM82494.1 - 3.7e-05 24.2 0.4 0.00069 20.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RRM_1 PF00076.22 EIM82494.1 - 0.00076 19.2 0.0 0.0056 16.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 EIM82494.1 - 0.0076 16.2 0.0 0.05 13.5 0.0 2.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EIM82494.1 - 0.038 14.1 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EIM82494.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM82494.1 - 0.16 12.3 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain APC_N_CC PF16689.5 EIM82494.1 - 0.18 11.9 0.7 35 4.6 0.0 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain F-box-like PF12937.7 EIM82495.1 - 0.00012 21.9 0.2 0.00064 19.6 0.2 2.2 1 1 0 1 1 1 1 F-box-like DUF974 PF06159.13 EIM82496.1 - 5.2e-77 259.0 0.0 8.1e-77 258.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Epimerase PF01370.21 EIM82500.1 - 5.1e-17 62.2 0.0 1.3e-16 60.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM82500.1 - 1e-10 41.1 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM82500.1 - 2.5e-08 34.0 0.2 6.4e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EIM82500.1 - 5.5e-08 32.6 0.1 9.1e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM82500.1 - 1.3e-07 31.4 0.3 1.7e-06 27.7 0.3 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM82500.1 - 3.1e-06 26.5 0.1 1.4e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EIM82500.1 - 0.14 11.6 0.1 0.47 9.9 0.0 2.0 3 0 0 3 3 3 0 short chain dehydrogenase DUF4536 PF15055.6 EIM82501.1 - 1.5e-05 25.1 1.2 1.9e-05 24.8 1.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) CHAT PF12770.7 EIM82502.1 - 7.6e-39 133.9 0.1 1.5e-38 132.9 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM82502.1 - 4.4e-11 42.3 21.8 0.2 11.6 0.1 11.1 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM82502.1 - 3.2e-09 36.3 0.2 2.1 8.8 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82502.1 - 2.7e-06 27.7 9.3 1.1 10.2 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82502.1 - 4.3e-06 26.9 30.9 1.7 9.0 0.1 11.8 9 3 5 14 14 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM82502.1 - 0.00048 20.0 8.8 22 5.5 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EIM82502.1 - 0.0013 18.5 0.0 8.5 6.1 0.0 4.1 2 2 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 OST-HTH PF12872.7 EIM82502.1 - 0.021 14.6 0.7 1.3 8.8 0.0 3.6 3 1 1 4 4 4 0 OST-HTH/LOTUS domain Sel1 PF08238.12 EIM82502.1 - 0.052 14.3 0.5 3.5 8.4 0.0 3.9 4 0 0 4 4 4 0 Sel1 repeat KRAP_IP3R_bind PF14722.6 EIM82502.1 - 0.074 12.8 0.0 9.7 5.9 0.0 2.9 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain TPR_1 PF00515.28 EIM82502.1 - 0.21 11.5 11.7 33 4.5 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM82502.1 - 0.99 9.6 19.0 86 3.5 0.0 9.7 12 1 0 12 12 11 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM82502.1 - 1.2 8.9 9.3 23 4.8 0.0 6.3 7 1 0 7 7 7 0 TPR repeat Vta1_C PF18097.1 EIM82502.1 - 2.1 8.1 16.2 3.2 7.5 0.1 5.6 6 0 0 6 6 6 0 Vta1 C-terminal domain V-ATPase_H_N PF03224.14 EIM82503.1 - 2.7e-85 286.4 0.1 1.4e-84 284.1 0.1 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EIM82503.1 - 3.5e-43 146.5 1.5 9.4e-43 145.1 0.1 2.4 3 0 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.22 EIM82503.1 - 6.7e-06 25.9 0.6 1 9.8 0.0 5.2 4 1 1 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 EIM82503.1 - 3.7e-05 22.5 0.1 0.035 12.7 0.0 2.4 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 EIM82503.1 - 4.9e-05 23.6 0.8 0.0029 18.0 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats Arm_2 PF04826.13 EIM82503.1 - 0.00011 21.8 0.0 0.00028 20.4 0.0 1.6 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 EIM82503.1 - 0.0014 18.6 0.5 2.9 8.1 0.2 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EIM82503.1 - 0.029 14.9 3.4 14 6.3 0.0 5.1 4 1 1 5 5 5 0 HEAT-like repeat DUF1344 PF07076.11 EIM82503.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Phage_int_SAM_1 PF02899.17 EIM82503.1 - 0.1 12.9 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain An_peroxidase PF03098.15 EIM82504.1 - 2.4e-31 108.9 0.0 1.1e-21 77.1 0.0 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EIM82504.1 - 7.1e-06 25.0 0.0 7.5e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 DUF2235 PF09994.9 EIM82505.1 - 1.3e-91 307.0 0.3 1.6e-91 306.7 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-FLZ PF04570.14 EIM82505.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 p450 PF00067.22 EIM82506.1 - 3.1e-30 105.3 0.0 1.3e-28 100.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FtsX PF02687.21 EIM82507.1 - 1.6 9.3 7.1 0.28 11.7 0.6 2.2 2 0 0 2 2 2 0 FtsX-like permease family p450 PF00067.22 EIM82508.1 - 3.8e-68 230.3 0.1 2.1e-67 227.9 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 Plavaka PF18759.1 EIM82509.1 - 1.1e-117 392.9 0.0 1.4e-117 392.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4197 PF13852.6 EIM82509.1 - 0.037 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) DDE_3 PF13358.6 EIM82511.1 - 2.8e-05 23.9 0.0 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Endonuclease_NS PF01223.23 EIM82513.1 - 3.5e-55 187.3 0.0 4.4e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF1118 PF06549.12 EIM82514.1 - 0.47 10.8 3.3 1.3 9.3 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) MRP-L46 PF11788.8 EIM82515.1 - 2.2e-16 60.6 0.0 5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EIM82515.1 - 2.4e-08 34.1 0.1 4.8e-08 33.1 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain R3H PF01424.22 EIM82516.1 - 9.6e-11 41.5 0.6 2.2e-10 40.4 0.1 1.9 2 0 0 2 2 2 1 R3H domain RRM_1 PF00076.22 EIM82516.1 - 2.1e-07 30.6 0.1 5.7e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4887 PF16228.5 EIM82516.1 - 1.3 9.2 7.9 4.5 7.4 7.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DNA_methylase PF00145.17 EIM82518.1 - 5.3e-30 104.9 0.0 1.2e-27 97.2 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase fn3 PF00041.21 EIM82518.1 - 0.0033 17.7 0.7 5 7.5 0.1 3.4 3 0 0 3 3 3 2 Fibronectin type III domain HOOK PF05622.12 EIM82519.1 - 1.7e-58 198.4 73.5 7.2e-57 193.0 51.9 3.4 1 1 1 2 2 2 2 HOOK protein NYD-SP28_assoc PF14775.6 EIM82519.1 - 0.0072 16.4 0.8 0.0072 16.4 0.8 4.9 5 0 0 5 5 5 1 Sperm tail C-terminal domain bZIP_1 PF00170.21 EIM82519.1 - 0.012 15.7 2.8 0.012 15.7 2.8 7.9 8 2 2 10 10 10 0 bZIP transcription factor DNA_methylase PF00145.17 EIM82520.1 - 6e-15 55.4 0.0 1.4e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase PITH PF06201.13 EIM82521.1 - 3e-39 134.7 0.2 4e-39 134.3 0.2 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EIM82521.1 - 2.9e-19 69.0 0.0 5.6e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EIM82521.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family C-C_Bond_Lyase PF15617.6 EIM82521.1 - 0.024 13.8 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Thioredoxin_2 PF13098.6 EIM82521.1 - 0.024 15.1 0.0 0.06 13.8 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIM82521.1 - 0.15 12.4 0.1 5.4 7.4 0.0 3.0 2 1 0 2 2 2 0 Thioredoxin-like Sugar_tr PF00083.24 EIM82522.1 - 4.2e-86 289.6 8.7 1.1e-85 288.2 8.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM82522.1 - 1.1e-22 80.5 19.2 1.1e-22 80.5 19.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM82522.1 - 1.4e-05 23.8 9.8 5.5e-05 21.8 4.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EIM82522.1 - 2.5e-05 23.1 26.7 0.00021 20.0 2.6 3.8 2 2 2 4 4 4 2 MFS/sugar transport protein F-box-like PF12937.7 EIM82523.1 - 2.3e-09 37.0 0.2 1.4e-08 34.5 0.2 2.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM82523.1 - 1.1 9.8 10.0 1.2 9.7 0.2 4.9 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 EIM82524.1 - 1.6e-24 86.6 69.1 4.2e-21 75.3 47.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMA7 PF09072.10 EIM82526.1 - 2.9e-22 79.2 24.5 3.2e-22 79.1 24.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF1645 PF07816.11 EIM82526.1 - 0.015 15.9 1.4 0.016 15.8 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Peptidase_S9 PF00326.21 EIM82527.1 - 2.7e-08 33.6 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EIM82527.1 - 0.0065 15.8 0.1 1.6 7.9 0.0 2.5 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EIM82527.1 - 0.069 13.0 0.1 1.6 8.5 0.0 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Not1 PF04054.15 EIM82528.1 - 4e-130 434.0 0.1 1e-129 432.6 0.1 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EIM82528.1 - 5.8e-96 320.2 4.4 1.4e-93 312.4 0.1 3.6 4 0 0 4 4 4 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EIM82528.1 - 6.7e-55 185.2 0.0 1.5e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EIM82528.1 - 1.3e-54 184.1 0.0 3.2e-54 182.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EIM82528.1 - 8.1e-45 152.6 0.1 2.2e-44 151.1 0.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FdhE PF04216.12 EIM82528.1 - 0.051 13.5 0.1 0.16 11.8 0.1 1.9 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF3528 PF12045.8 EIM82528.1 - 0.096 13.3 0.0 0.36 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3528) IMUP PF15761.5 EIM82529.1 - 10 6.9 7.0 1.9 9.2 1.2 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein Thg1 PF04446.12 EIM82530.1 - 6e-49 165.2 0.1 9.4e-49 164.6 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EIM82530.1 - 1.5e-45 154.3 0.1 2.3e-45 153.7 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain SbmA_BacA PF05992.12 EIM82530.1 - 0.015 14.8 1.5 0.26 10.7 0.2 2.1 2 0 0 2 2 2 0 SbmA/BacA-like family Med3 PF11593.8 EIM82530.1 - 0.1 11.8 3.3 0.15 11.2 3.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Steroid_dh PF02544.16 EIM82531.1 - 3.1e-39 134.3 0.6 5e-39 133.7 0.6 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 EIM82531.1 - 6e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EIM82531.1 - 0.00099 19.8 0.2 0.0018 18.9 0.2 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 EIM82531.1 - 0.022 15.2 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain ThiS PF02597.20 EIM82531.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 ThiS family Acyl-CoA_dh_M PF02770.19 EIM82533.1 - 1.6e-05 25.0 0.0 8.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Tmem26 PF09772.9 EIM82534.1 - 0.03 13.7 3.6 0.059 12.7 3.6 1.5 1 0 0 1 1 1 0 Transmembrane protein 26 DUF1980 PF09323.10 EIM82534.1 - 1.9 8.3 8.2 0.71 9.8 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Alpha-amylase PF00128.24 EIM82537.1 - 1.5e-51 175.9 0.5 3.1e-51 174.9 0.5 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EIM82537.1 - 2.7e-15 56.4 0.1 6.5e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Pkinase_fungal PF17667.1 EIM82539.1 - 2.4e-49 168.2 0.0 2.8e-30 105.4 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EIM82539.1 - 0.0096 15.9 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM82539.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Fasciclin PF02469.22 EIM82540.1 - 4.6e-29 101.2 0.1 8.7e-13 48.6 0.0 3.9 3 1 0 3 3 3 3 Fasciclin domain IPPT PF01715.17 EIM82541.1 - 2.8e-52 177.8 0.0 7.8e-27 94.6 0.0 3.4 4 0 0 4 4 4 2 IPP transferase AAA_22 PF13401.6 EIM82541.1 - 0.019 15.3 0.4 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EIM82541.1 - 0.054 14.0 0.0 0.054 14.0 0.0 3.3 3 1 0 3 3 3 0 AAA domain CPSF100_C PF13299.6 EIM82541.1 - 0.46 10.6 12.4 0.93 9.6 12.4 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EIM82541.1 - 1.1 7.4 19.9 33 2.6 22.2 1.9 2 0 0 2 2 2 0 CDC45-like protein Ribosomal_L27A PF00828.19 EIM82542.1 - 3.7e-33 114.9 0.1 5.9e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Plavaka PF18759.1 EIM82544.1 - 1.5e-112 376.0 0.0 2e-112 375.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SapB_1 PF05184.15 EIM82544.1 - 0.53 10.4 1.3 0.63 10.1 0.0 1.8 2 0 0 2 2 2 0 Saposin-like type B, region 1 p450 PF00067.22 EIM82547.1 - 1.2e-67 228.7 0.0 1.5e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82550.1 - 3.4e-53 181.0 0.0 7.2e-49 166.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 RhoGEF67_u2 PF16614.5 EIM82550.1 - 0.041 14.0 0.1 0.076 13.1 0.1 1.4 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 DUF2656 PF10847.8 EIM82550.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) p450 PF00067.22 EIM82551.1 - 1.5e-07 30.6 0.0 1.6e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EIM82552.1 - 1.7e-21 76.6 53.2 3.3e-21 75.6 35.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 EIM82552.1 - 2.7 8.4 11.7 1 9.8 0.7 3.4 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Abhydrolase_6 PF12697.7 EIM82553.1 - 1.6e-09 38.7 0.0 2.1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 EIM82555.1 - 1.8e-21 76.4 0.0 2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82556.1 - 3e-05 23.0 0.0 3.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.24 EIM82557.1 - 8.1e-24 84.8 25.8 1.2e-23 84.3 25.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase ICMT PF04140.14 EIM82558.1 - 5.5e-15 55.6 0.1 1.4e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM82558.1 - 5.8e-13 49.2 0.1 3.1e-11 43.6 0.1 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM82558.1 - 9.8e-06 24.6 0.1 1.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FA_desaturase PF00487.24 EIM82559.1 - 1.6e-30 106.8 23.6 2.4e-30 106.2 23.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase FA_desaturase PF00487.24 EIM82560.1 - 1.6e-28 100.3 21.5 1.6e-28 100.3 21.5 1.6 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EIM82560.1 - 0.00011 22.5 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Amino_oxidase PF01593.24 EIM82561.1 - 2.6e-41 142.4 0.0 3.8e-41 141.8 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIM82561.1 - 9.1e-10 38.6 0.1 2.2e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM82561.1 - 0.003 17.6 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EIM82561.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM82561.1 - 0.12 11.2 0.2 1.7 7.4 0.0 2.5 2 1 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 EIM82561.1 - 0.18 11.4 2.4 0.19 11.3 0.8 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase Striatin PF08232.12 EIM82562.1 - 2e-51 174.6 11.3 5.9e-50 169.9 0.0 3.6 5 0 0 5 5 5 1 Striatin family WD40 PF00400.32 EIM82562.1 - 1.5e-35 120.6 6.9 5.1e-07 30.3 1.3 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM82562.1 - 4.2e-08 33.4 0.2 1.3 9.4 0.0 5.2 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 EIM82562.1 - 0.0062 16.6 26.0 0.0062 16.6 26.0 3.1 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Nucleoporin_N PF08801.11 EIM82562.1 - 0.0094 14.7 0.0 0.13 11.0 0.0 2.3 2 0 0 2 2 2 1 Nup133 N terminal like Nup160 PF11715.8 EIM82562.1 - 0.14 10.7 0.0 14 4.2 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 V_ATPase_I PF01496.19 EIM82562.1 - 1.9 6.3 4.0 3 5.6 4.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0240 PF06784.11 EIM82562.1 - 1.9 8.5 8.5 4.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) PDEase_II PF02112.15 EIM82563.1 - 2.2e-41 142.1 0.0 2.6e-38 132.0 0.0 2.4 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EIM82563.1 - 3.3e-05 23.5 0.1 0.00038 20.0 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM82563.1 - 0.072 13.1 0.4 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily EF-hand_4 PF12763.7 EIM82565.1 - 9.6e-38 128.3 0.0 1.4e-15 57.1 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EIM82565.1 - 3.7e-07 30.5 0.0 0.0036 17.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EIM82565.1 - 1.1e-05 24.6 0.0 0.46 10.1 0.0 3.6 3 0 0 3 3 3 2 EF hand UBA PF00627.31 EIM82565.1 - 2e-05 24.4 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 EIM82565.1 - 0.0047 16.7 0.0 5.6 7.2 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 EIM82565.1 - 0.02 14.7 0.0 4.1 7.3 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair Fib_alpha PF08702.10 EIM82565.1 - 0.17 12.0 7.3 0.16 12.2 5.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EIM82565.1 - 2 8.4 28.0 0.029 14.4 8.2 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.11 EIM82565.1 - 2.2 6.9 32.5 10 4.7 32.5 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.12 EIM82565.1 - 2.7 8.1 31.6 2 8.5 13.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 EIM82565.1 - 3.9 6.3 24.0 55 2.4 24.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 EIM82565.1 - 4.6 6.0 27.9 0.51 9.2 15.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 EIM82565.1 - 5.2 7.2 29.8 57 3.9 29.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EIM82565.1 - 6.8 6.8 24.8 1.3 9.1 7.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 EIM82565.1 - 8.5 5.4 25.2 4.4 6.3 13.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UQ_con PF00179.26 EIM82566.1 - 7.9e-44 148.7 0.1 9.6e-44 148.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EIM82566.1 - 1.3e-05 25.4 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EIM82566.1 - 0.0016 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B MFS_1 PF07690.16 EIM82568.1 - 1.9e-06 27.0 62.9 1.4e-05 24.2 56.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM82568.1 - 0.0013 17.2 32.1 0.008 14.6 32.1 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) S1FA PF04689.13 EIM82568.1 - 0.21 11.7 0.5 0.92 9.7 0.1 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA MFS_1 PF07690.16 EIM82569.1 - 1.7e-08 33.8 57.4 4.8e-05 22.5 40.4 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM82569.1 - 1.4e-05 23.7 30.3 0.00013 20.5 30.3 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 EIM82571.1 - 2.6e-10 39.7 0.0 3e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82572.1 - 3.4e-43 148.1 0.0 4.4e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82573.1 - 9.1e-50 169.7 0.0 1.2e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 EIM82574.1 - 5.3e-21 75.4 0.1 1.4e-20 74.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM82574.1 - 5.7e-11 43.4 0.0 7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM82574.1 - 3.2e-08 33.2 0.0 2.5e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 EIM82574.1 - 0.073 13.2 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 EIM82574.1 - 0.099 11.9 0.1 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 EIM82574.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.21 EIM82575.1 - 8.3e-19 68.0 0.0 2.2e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM82575.1 - 2.6e-09 36.9 0.0 3.7e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM82575.1 - 2.4e-07 30.1 0.0 5.2e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM82575.1 - 0.00032 19.9 0.0 0.0029 16.8 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EIM82575.1 - 0.0095 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EIM82575.1 - 0.068 12.6 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase RTC PF01137.21 EIM82576.1 - 3.9e-78 261.7 0.0 5.6e-77 257.9 0.0 1.9 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EIM82576.1 - 5e-19 68.7 0.0 9.3e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CDC50 PF03381.15 EIM82577.1 - 1e-92 310.6 0.1 1.7e-92 309.9 0.1 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family BLF1 PF17752.1 EIM82579.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Burkholderia lethal factor 1 Pkinase_fungal PF17667.1 EIM82580.1 - 1.5e-49 168.9 0.0 2.3e-33 115.6 0.1 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EIM82580.1 - 1.4e-07 31.7 0.0 4e-05 23.7 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 EIM82580.1 - 1.8e-07 30.8 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2534 PF10749.9 EIM82580.1 - 0.089 13.0 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) PHD PF00628.29 EIM82582.1 - 4.7e-17 61.6 15.3 3.3e-11 42.9 4.1 2.7 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 EIM82582.1 - 0.0012 18.4 2.7 0.024 14.3 0.7 2.4 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 EIM82582.1 - 0.005 17.1 4.1 0.0077 16.5 1.4 2.3 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EIM82582.1 - 0.027 14.0 14.6 0.18 11.4 0.9 3.5 3 1 0 3 3 3 0 PHD-finger CIAPIN1 PF05093.13 EIM82582.1 - 0.033 14.7 0.6 3.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis C1_1 PF00130.22 EIM82582.1 - 0.083 12.8 9.2 2.2 8.3 0.2 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 EIM82582.1 - 0.15 12.2 3.3 0.11 12.7 0.7 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD_4 PF16866.5 EIM82582.1 - 2.6 8.2 12.6 3.4 7.8 1.1 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 EIM82582.1 - 7.7 6.9 9.4 7.4 7.0 0.7 2.8 2 1 0 2 2 2 0 RING-like domain Acyltransferase PF01553.21 EIM82583.1 - 1.6e-15 56.9 0.0 2.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase F-box-like PF12937.7 EIM82584.1 - 8.2e-09 35.2 0.8 2.4e-08 33.7 0.8 1.9 1 0 0 1 1 1 1 F-box-like DUF2076 PF09849.9 EIM82585.1 - 0.057 13.4 25.0 0.072 13.1 1.4 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) ATP-synt_ab PF00006.25 EIM82586.1 - 4.7e-109 363.0 0.0 6.8e-109 362.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EIM82586.1 - 4.7e-42 142.7 0.0 9.1e-42 141.8 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EIM82586.1 - 2e-14 53.8 3.1 5.5e-14 52.4 3.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EIM82587.1 - 1.8e-40 138.4 0.0 3.8e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.9 EIM82587.1 - 1e-33 116.5 0.0 1.9e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EIM82587.1 - 5.3e-10 39.8 0.0 2.4e-07 31.2 0.0 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_lid_3 PF17862.1 EIM82587.1 - 3.7e-06 26.7 0.3 1.6e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EIM82587.1 - 0.00017 21.6 0.0 0.00048 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM82587.1 - 0.00035 20.8 0.0 0.0098 16.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EIM82587.1 - 0.00077 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EIM82587.1 - 0.0018 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EIM82587.1 - 0.0028 18.1 0.1 0.029 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EIM82587.1 - 0.015 15.5 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 EIM82587.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EIM82587.1 - 0.036 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EIM82587.1 - 0.038 14.1 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EIM82587.1 - 0.11 11.7 0.1 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EIM82587.1 - 0.12 11.8 0.5 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EIM82587.1 - 0.12 12.9 0.0 0.38 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 EIM82587.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EIM82587.1 - 0.13 12.4 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EIM82587.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ING PF12998.7 EIM82589.1 - 1.5e-11 44.8 0.0 0.00011 22.7 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EIM82589.1 - 1.9e-05 24.5 8.5 3.1e-05 23.8 8.5 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIM82589.1 - 0.17 11.5 4.3 0.31 10.7 4.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 EIM82589.1 - 0.78 10.0 3.3 2 8.7 3.4 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain ADH_zinc_N_2 PF13602.6 EIM82590.1 - 6.4e-21 75.8 0.0 1.2e-20 74.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EIM82590.1 - 9.1e-09 35.4 0.0 3e-08 33.7 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase zf-MYND PF01753.18 EIM82591.1 - 4.4e-08 33.1 11.4 1e-07 31.9 11.4 1.7 1 0 0 1 1 1 1 MYND finger SEC-C PF02810.15 EIM82591.1 - 7.2e-05 22.6 11.7 0.00039 20.3 4.7 2.5 2 0 0 2 2 2 2 SEC-C motif zf-C6H2 PF15801.5 EIM82591.1 - 0.82 10.0 9.3 1.7 9.0 9.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gar1 PF04410.14 EIM82592.1 - 1.9e-37 128.4 0.0 2.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 EIM82593.1 - 5.4e-61 204.8 0.0 3.9e-44 150.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM82593.1 - 1.5e-11 43.9 7.0 6.2e-05 22.7 0.1 3.6 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EIM82593.1 - 1.7e-10 41.6 0.4 0.0067 16.8 0.0 5.0 5 0 0 5 5 5 2 AAA ATPase domain AAA_5 PF07728.14 EIM82593.1 - 2.3e-07 30.9 0.1 0.029 14.4 0.1 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EIM82593.1 - 4.9e-06 27.1 0.0 0.019 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EIM82593.1 - 5.4e-06 26.2 0.0 0.0035 17.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EIM82593.1 - 1.5e-05 24.4 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EIM82593.1 - 4.8e-05 23.7 0.2 0.02 15.2 0.1 3.3 2 1 1 3 3 3 1 AAA domain TsaE PF02367.17 EIM82593.1 - 5.6e-05 23.1 0.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EIM82593.1 - 6.1e-05 23.1 0.0 0.57 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EIM82593.1 - 8.9e-05 22.4 0.0 0.003 17.5 0.0 3.2 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain AAA_6 PF12774.7 EIM82593.1 - 0.00026 20.1 0.1 0.0079 15.2 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EIM82593.1 - 0.00031 20.9 0.0 0.33 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EIM82593.1 - 0.00069 19.4 0.0 0.98 9.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.14 EIM82593.1 - 0.00071 19.7 0.0 0.023 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EIM82593.1 - 0.00078 19.0 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EIM82593.1 - 0.0008 19.2 0.0 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EIM82593.1 - 0.00082 19.7 0.0 0.11 12.9 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 EIM82593.1 - 0.0013 19.0 0.0 0.41 10.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EIM82593.1 - 0.0015 18.3 0.1 0.19 11.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EIM82593.1 - 0.0019 17.6 0.2 0.043 13.2 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EIM82593.1 - 0.002 17.2 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EIM82593.1 - 0.0078 15.8 3.6 0.01 15.4 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_3 PF07726.11 EIM82593.1 - 0.011 15.6 0.0 0.61 9.9 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EIM82593.1 - 0.016 14.7 0.1 0.087 12.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Cytidylate_kin PF02224.18 EIM82593.1 - 0.017 14.9 2.8 2 8.1 0.0 3.4 4 0 0 4 4 4 0 Cytidylate kinase Rad17 PF03215.15 EIM82593.1 - 0.025 14.5 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 EIM82593.1 - 0.029 13.5 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 EIM82593.1 - 0.034 14.1 1.9 3.2 7.7 0.1 3.5 3 0 0 3 3 3 0 NACHT domain ATPase PF06745.13 EIM82593.1 - 0.034 13.5 0.1 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 EIM82593.1 - 0.045 14.2 0.5 13 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EIM82593.1 - 0.046 12.8 0.0 0.92 8.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.6 EIM82593.1 - 0.053 13.3 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EIM82593.1 - 0.086 12.5 0.0 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EIM82593.1 - 0.11 12.4 0.1 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EIM82593.1 - 0.19 10.9 0.0 3.7 6.7 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain SKI PF01202.22 EIM82593.1 - 0.2 11.8 1.0 13 5.9 0.0 2.8 3 0 0 3 3 3 0 Shikimate kinase PhoD PF09423.10 EIM82594.1 - 5.2e-36 124.4 0.1 2e-35 122.5 0.1 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 EIM82594.1 - 0.38 11.4 3.1 0.48 11.0 0.0 2.7 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain DUF1690 PF07956.11 EIM82595.1 - 2.8e-31 108.8 2.0 3.8e-31 108.4 2.0 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 EIM82595.1 - 0.0027 17.8 6.1 0.0068 16.5 6.1 1.6 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Fungal_trans PF04082.18 EIM82597.1 - 7.5e-11 41.6 0.5 1.8e-10 40.3 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM82597.1 - 4.3e-06 26.8 11.6 4.3e-06 26.8 11.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EIM82598.1 - 0.0054 17.5 3.7 0.073 14.0 0.2 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ADK PF00406.22 EIM82599.1 - 2.6e-45 154.2 0.4 7.7e-45 152.7 0.4 1.7 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EIM82599.1 - 5.4e-32 111.1 0.1 8.8e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM82599.1 - 1.3e-11 45.2 0.1 1.8e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EIM82599.1 - 4.6e-06 26.4 0.9 0.08 12.6 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EIM82599.1 - 0.00073 19.7 0.0 0.0077 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EIM82599.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PAS_7 PF12860.7 EIM82599.1 - 0.055 13.6 0.2 0.56 10.4 0.1 2.1 2 0 0 2 2 2 0 PAS fold Zeta_toxin PF06414.12 EIM82599.1 - 0.067 12.5 0.4 0.2 10.9 0.0 2.0 2 1 0 2 2 2 0 Zeta toxin DEC-1_N PF04625.13 EIM82599.1 - 1.6 7.6 5.0 2.3 7.1 5.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CN_hydrolase PF00795.22 EIM82600.1 - 2.9e-55 187.4 0.0 3.8e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ_C PF01556.18 EIM82601.1 - 1e-40 139.2 0.3 1.3e-40 138.8 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIM82601.1 - 1.3e-20 73.3 0.7 2.2e-20 72.6 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIM82601.1 - 2.9e-16 59.6 15.5 5e-16 58.8 15.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EIM82601.1 - 0.035 14.1 12.5 0.11 12.5 1.8 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EIM82601.1 - 9.2 6.3 11.0 10 6.2 2.5 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Glyco_hydro_3_C PF01915.22 EIM82602.1 - 1.1e-67 227.9 0.0 1.7e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM82602.1 - 4.1e-46 157.8 0.0 6.3e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM82602.1 - 4.6e-23 81.1 0.0 1.2e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EIM82602.1 - 2.5e-12 46.9 0.0 4.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 PA14 domain HA2 PF04408.23 EIM82605.1 - 0.22 11.8 1.4 2.3 8.5 0.5 2.3 2 0 0 2 2 2 0 Helicase associated domain (HA2) MFS_1 PF07690.16 EIM82610.1 - 2.4e-14 53.0 43.1 2.4e-14 53.0 43.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM82610.1 - 2.1e-05 23.6 22.2 4.6e-05 22.5 9.8 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter TMEM100 PF16311.5 EIM82610.1 - 0.92 9.1 5.7 0.26 10.9 1.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2236 PF09995.9 EIM82611.1 - 7e-07 29.7 0.2 1.1e-06 29.0 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) ADH_N PF08240.12 EIM82612.1 - 4.4e-25 87.7 9.1 7.3e-25 87.0 9.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM82612.1 - 8.5e-15 54.9 0.0 3.1e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIM82612.1 - 0.00093 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EIM82612.1 - 0.0036 16.7 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain S1-P1_nuclease PF02265.16 EIM82613.1 - 1e-62 212.3 0.0 1.1e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Nop25 PF09805.9 EIM82614.1 - 2.4e-22 79.9 9.9 2.4e-22 79.9 9.9 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) MCPVI PF02993.14 EIM82615.1 - 4.8 6.9 9.4 0.58 10.0 4.7 1.8 2 0 0 2 2 2 0 Minor capsid protein VI R3H PF01424.22 EIM82616.1 - 3.7e-15 55.7 0.0 9.3e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EIM82616.1 - 2.3e-05 24.2 0.3 6.6e-05 22.7 0.3 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EIM82616.1 - 0.00016 21.7 0.2 0.00067 19.7 0.2 2.1 1 0 0 1 1 1 1 G-patch domain DUF3107 PF11305.8 EIM82616.1 - 0.073 13.3 0.1 0.29 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Amidase PF01425.21 EIM82617.1 - 9.1e-65 219.4 0.1 1.2e-62 212.4 0.0 2.2 2 0 0 2 2 2 2 Amidase PEPCK_ATP PF01293.20 EIM82618.1 - 2.9e-219 728.5 0.0 3.5e-219 728.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.6 EIM82618.1 - 0.1 12.3 0.1 0.31 10.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EIM82618.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EIM82618.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 EIM82619.1 - 4.4e-05 23.7 0.0 6.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM82619.1 - 0.006 17.0 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EIM82619.1 - 0.03 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 EIM82619.1 - 0.033 14.3 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 EIM82619.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EIM82619.1 - 0.065 12.7 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase DnaJ PF00226.31 EIM82620.1 - 1.4e-22 79.6 2.4 5.6e-22 77.6 0.2 2.8 3 0 0 3 3 3 1 DnaJ domain RGCC PF15151.6 EIM82620.1 - 0.0073 16.5 1.1 0.017 15.3 1.1 1.6 1 0 0 1 1 1 1 Response gene to complement 32 protein family Yae1_N PF09811.9 EIM82621.1 - 9.2e-05 22.1 6.7 0.00012 21.7 2.8 2.5 1 1 1 2 2 2 1 Essential protein Yae1, N terminal rhaM PF05336.13 EIM82621.1 - 0.033 14.2 1.7 0.1 12.7 1.7 1.9 1 0 0 1 1 1 0 L-rhamnose mutarotase TMF_TATA_bd PF12325.8 EIM82621.1 - 0.078 13.2 13.5 0.07 13.4 11.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 EIM82621.1 - 0.12 10.2 6.1 0.17 9.8 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VSG_B PF13206.6 EIM82621.1 - 1.5 8.0 10.8 2.2 7.4 10.8 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain ERM PF00769.19 EIM82621.1 - 4.3 7.1 33.6 9.4 6.0 33.6 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 EIM82621.1 - 7.1 6.7 8.3 11 6.0 8.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WDCP PF15390.6 EIM82621.1 - 7.8 4.7 5.8 11 4.3 5.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ADIP PF11559.8 EIM82621.1 - 8.8 6.4 17.7 2.3 8.3 13.2 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding p450 PF00067.22 EIM82622.1 - 6.2e-54 183.5 0.0 1.1e-53 182.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM82623.1 - 6.2e-55 186.8 0.0 9.1e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ubiquitin PF00240.23 EIM82624.1 - 1.5e-170 553.2 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 EIM82624.1 - 2.6e-78 257.8 27.8 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIM82624.1 - 3e-28 98.1 12.9 0.00064 20.1 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EIM82624.1 - 1.7e-19 69.6 5.6 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EIM82624.1 - 1.2e-17 64.0 4.5 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EIM82624.1 - 2.7e-17 62.9 12.0 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 EIM82624.1 - 5.6e-16 59.0 2.3 0.49 11.0 0.0 5.2 1 1 1 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EIM82624.1 - 3.9e-12 46.3 0.7 1.8 8.4 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 EIM82624.1 - 3.7e-09 36.2 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 EIM82624.1 - 1.2e-07 31.7 32.7 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 EIM82624.1 - 1.6e-07 32.0 0.6 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 EIM82624.1 - 1.9e-07 31.3 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 EIM82624.1 - 4.7e-07 29.8 0.1 40 4.4 0.0 5.8 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 EIM82624.1 - 5.8e-07 29.6 5.6 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EIM82624.1 - 1.2e-06 28.2 6.5 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 EIM82624.1 - 4.3e-06 26.8 6.0 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EIM82624.1 - 2.5e-05 23.8 0.2 29 4.0 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 EIM82624.1 - 6e-05 23.6 2.2 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 EIM82624.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EIM82624.1 - 0.00069 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EIM82624.1 - 0.008 16.3 8.5 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 EIM82624.1 - 0.052 13.4 13.5 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 EIM82624.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 EIM82624.1 - 0.47 11.0 12.5 1e+02 3.5 0.1 4.9 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 EIM82624.1 - 2.4 8.4 7.6 3.2e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR PI3K_p85B PF02192.16 EIM82624.1 - 3 7.6 12.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 EIM82624.1 - 3.1 8.0 14.4 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 EIM82624.1 - 5.8 6.9 11.7 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e FAM72 PF14976.6 EIM82625.1 - 6.2e-05 23.2 4.6 0.00018 21.7 4.6 1.6 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 EIM82625.1 - 0.032 14.4 0.3 0.038 14.2 0.3 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Flavin_Reduct PF01613.18 EIM82626.1 - 7.6e-21 74.8 0.6 1.3e-20 74.0 0.6 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EIM82626.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Mg_trans_NIPA PF05653.14 EIM82627.1 - 8.7e-16 57.9 12.7 6.8e-08 32.0 5.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EIM82627.1 - 0.00016 21.9 7.1 0.00016 21.9 7.1 3.3 3 1 0 3 3 3 2 EamA-like transporter family Neur_chan_memb PF02932.16 EIM82627.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 EIM82628.1 - 0.56 10.2 18.4 0.73 9.8 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RdRP PF05183.12 EIM82629.1 - 2.5e-106 356.7 0.0 4.4e-106 355.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.6 EIM82629.1 - 8.6e-42 143.0 0.0 2e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM82629.1 - 4.1e-08 33.3 7.6 0.02 14.7 0.1 4.3 1 1 3 4 4 4 3 AAA domain UvrD_C_2 PF13538.6 EIM82629.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Mt_ATP-synt_D PF05873.12 EIM82629.1 - 0.11 12.4 0.1 13 5.6 0.0 2.6 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Poxvirus PF06227.12 EIM82629.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus AAA_28 PF13521.6 EIM82630.1 - 3.2e-21 76.2 0.0 3.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM82630.1 - 0.00015 22.3 0.0 0.00022 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EIM82630.1 - 0.00058 20.3 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EIM82630.1 - 0.00085 19.4 0.0 0.0019 18.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EIM82630.1 - 0.0014 19.2 0.0 0.0016 19.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TsaE PF02367.17 EIM82630.1 - 0.0034 17.4 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EIM82630.1 - 0.0035 17.8 0.0 0.0051 17.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EIM82630.1 - 0.005 17.0 0.0 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM82630.1 - 0.0068 16.8 0.1 0.0074 16.7 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 EIM82630.1 - 0.0099 15.6 0.1 0.023 14.4 0.1 1.6 1 1 0 1 1 1 1 Cytidylate kinase AAA_22 PF13401.6 EIM82630.1 - 0.012 15.9 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIM82630.1 - 0.024 15.0 0.0 0.038 14.4 0.0 1.5 1 1 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 EIM82630.1 - 0.03 14.4 0.0 0.074 13.1 0.0 1.6 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 EIM82630.1 - 0.04 13.8 0.0 0.074 13.0 0.0 1.4 1 1 0 1 1 1 0 RsgA GTPase APS_kinase PF01583.20 EIM82630.1 - 0.049 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Guanylate_kin PF00625.21 EIM82630.1 - 0.05 13.3 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase PduV-EutP PF10662.9 EIM82630.1 - 0.051 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EIM82630.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EIM82630.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EIM82630.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EIM82630.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.7 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EIM82630.1 - 0.19 11.5 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EIM82631.1 - 1.6e-34 119.4 21.1 1.6e-34 119.4 21.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM82631.1 - 1.2e-07 31.0 11.5 1.6e-07 30.6 11.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter U79_P34 PF03064.16 EIM82633.1 - 0.97 8.7 8.6 1.4 8.2 8.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pyocin_S PF06958.12 EIM82633.1 - 4.1 8.0 11.0 19 5.8 0.1 3.2 3 0 0 3 3 3 0 S-type Pyocin Alpha_GJ PF03229.13 EIM82634.1 - 0.0091 16.5 10.6 0.0091 16.5 10.6 3.7 1 1 2 3 3 3 1 Alphavirus glycoprotein J DUF4051 PF13260.6 EIM82634.1 - 0.25 11.1 0.0 0.4 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF5585 PF17823.1 EIM82634.1 - 0.46 9.4 73.0 0.66 8.9 73.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) GREB1 PF15782.5 EIM82634.1 - 4.4 4.3 11.1 5.4 4.0 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Utp14 PF04615.13 EIM82634.1 - 6.3 5.2 6.7 7.1 5.1 6.7 1.1 1 0 0 1 1 1 0 Utp14 protein E1-E2_ATPase PF00122.20 EIM82635.1 - 1.3e-28 99.8 0.0 3.9e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 EIM82635.1 - 1.9e-21 76.5 0.0 3.5e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EIM82635.1 - 1.6e-17 64.5 1.1 7.7e-08 32.9 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EIM82635.1 - 6.3e-08 32.5 6.8 6.3e-08 32.5 6.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EIM82635.1 - 1.4e-05 25.1 0.1 2.5e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EIM82635.1 - 0.00015 21.3 0.0 0.00037 20.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus CHCH PF06747.13 EIM82636.1 - 4e-06 26.8 4.6 6.2e-06 26.2 4.6 1.3 1 0 0 1 1 1 1 CHCH domain PAP1 PF08601.10 EIM82636.1 - 0.092 12.5 14.0 0.2 11.4 3.9 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 DUF3801 PF12687.7 EIM82636.1 - 2.9 7.9 5.6 0.69 10.0 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) 3Beta_HSD PF01073.19 EIM82637.1 - 6.8e-11 41.7 0.0 9.7e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM82637.1 - 7.8e-10 38.6 0.0 2e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM82637.1 - 6.3e-06 25.8 0.6 0.00027 20.5 0.0 2.6 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM82637.1 - 2.6e-05 23.5 0.1 0.00015 21.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EIM82637.1 - 0.0036 16.8 0.1 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EIM82637.1 - 0.0057 16.2 0.2 0.19 11.3 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family Fe-ADH PF00465.19 EIM82638.1 - 3.5e-69 233.4 0.0 4.4e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EIM82638.1 - 9.5e-14 51.7 0.1 5.5e-13 49.2 0.1 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cupin_2 PF07883.11 EIM82639.1 - 1.2e-11 44.1 0.1 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EIM82639.1 - 2.1e-05 24.5 0.1 0.23 11.4 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 EIM82639.1 - 0.0035 17.5 0.4 0.47 10.7 0.1 2.3 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_3 PF05899.12 EIM82639.1 - 0.011 15.4 0.0 0.071 12.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) EutQ PF06249.12 EIM82639.1 - 0.027 14.2 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Mito_carr PF00153.27 EIM82640.1 - 2.3e-50 168.5 3.1 1.3e-17 63.4 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Pilus_CpaD PF09476.10 EIM82640.1 - 0.07 12.9 1.2 4.9 6.8 0.3 2.6 3 0 0 3 3 3 0 Pilus biogenesis CpaD protein (pilus_cpaD) MFS_1 PF07690.16 EIM82644.1 - 5.6e-16 58.4 50.3 3.2e-09 36.2 33.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD-oxidase_C PF02913.19 EIM82645.1 - 4.8e-54 183.6 0.0 7.6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EIM82645.1 - 1.4e-29 102.6 0.4 5.4e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Plavaka PF18759.1 EIM82649.1 - 1.6e-35 122.9 0.0 6.6e-35 120.9 0.0 1.8 1 1 0 1 1 1 1 Plavaka transposase MFS_1 PF07690.16 EIM82651.1 - 3.4e-36 124.9 29.9 3.4e-36 124.9 29.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 EIM82652.1 - 6.2e-16 59.2 0.0 1.3e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM82652.1 - 6.5e-13 49.0 0.0 3.1e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Lyase_aromatic PF00221.19 EIM82653.1 - 8.8e-150 499.4 0.9 1.1e-149 499.0 0.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Abhydrolase_6 PF12697.7 EIM82654.1 - 4.1e-15 57.0 0.1 5.6e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.22 EIM82654.1 - 0.081 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Beta-lactamase PF00144.24 EIM82654.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase adh_short PF00106.25 EIM82656.1 - 3.5e-29 101.7 0.0 8.8e-26 90.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM82656.1 - 6.9e-18 65.1 0.0 3.4e-16 59.5 0.0 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM82656.1 - 7.3e-09 35.8 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM82656.1 - 0.0038 16.7 0.1 0.0053 16.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family QRPTase_C PF01729.19 EIM82656.1 - 0.0042 16.9 0.0 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Shikimate_DH PF01488.20 EIM82656.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EIM82656.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF765 PF05570.11 EIM82656.1 - 0.2 11.9 2.6 0.41 10.9 2.6 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) Amidohydro_2 PF04909.14 EIM82657.1 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Pec_lyase_C PF00544.19 EIM82658.1 - 1.5e-35 122.7 7.2 2e-35 122.3 7.2 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EIM82658.1 - 8.2e-09 35.5 10.1 6.1e-07 29.4 6.1 2.2 2 0 0 2 2 2 2 Right handed beta helix region DUF262 PF03235.14 EIM82659.1 - 1.9e-13 51.1 0.1 4.2e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF262 Tcp11 PF05794.13 EIM82660.1 - 1.2e-17 64.1 0.0 1.7e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 T-complex protein 11 DUF2388 PF09498.10 EIM82660.1 - 0.08 12.9 0.3 0.94 9.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2388) GlutR_dimer PF00745.20 EIM82660.1 - 0.089 13.2 1.1 14 6.2 0.0 3.5 2 1 2 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain FliT PF05400.13 EIM82660.1 - 5.7 7.8 6.2 1.5 9.7 0.4 3.0 4 0 0 4 4 4 0 Flagellar protein FliT SGL PF08450.12 EIM82661.1 - 5.9e-07 29.3 0.0 8.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EIM82661.1 - 0.00021 21.4 0.0 0.0034 17.5 0.0 2.8 4 0 0 4 4 4 1 Arylesterase Reg_prop PF07494.11 EIM82661.1 - 0.12 12.7 0.0 5.2 7.6 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller NHL PF01436.21 EIM82661.1 - 4.7 7.4 5.1 31 4.8 0.0 3.9 5 0 0 5 5 5 0 NHL repeat Phage_antiter_Q PF06323.11 EIM82662.1 - 0.59 9.6 5.1 0.98 8.9 1.7 2.0 1 1 1 2 2 2 0 Phage antitermination protein Q DDE_3 PF13358.6 EIM82663.1 - 2e-08 34.1 0.1 4.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease Pec_lyase_C PF00544.19 EIM82664.1 - 1.4e-36 126.0 8.8 1.9e-36 125.7 8.8 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EIM82664.1 - 4.6e-05 23.3 13.8 0.0023 17.8 13.2 2.3 1 1 0 1 1 1 1 Right handed beta helix region Dcc1 PF09724.9 EIM82665.1 - 7.5e-84 281.9 0.0 8.5e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 FAD_binding_3 PF01494.19 EIM82666.1 - 8.4e-08 31.8 0.0 9.1e-07 28.4 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM82666.1 - 0.0077 16.4 0.0 0.024 14.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM82666.1 - 0.13 11.3 1.3 0.14 11.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EIM82669.1 - 3e-10 39.9 0.0 9.9e-09 34.9 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EIM82669.1 - 2.8e-08 33.9 0.4 6.8e-08 32.6 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM82669.1 - 5e-06 26.3 6.4 4.5e-05 23.2 1.5 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM82669.1 - 1.5e-05 24.3 0.5 2.4e-05 23.6 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM82669.1 - 4.1e-05 23.0 0.2 0.00044 19.6 0.2 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM82669.1 - 0.0002 21.9 0.1 0.13 12.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM82669.1 - 0.0013 17.9 0.0 0.0053 15.9 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EIM82669.1 - 0.0084 14.9 0.2 0.013 14.2 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EIM82669.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EIM82669.1 - 0.033 13.3 0.3 0.056 12.5 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EIM82669.1 - 0.058 13.4 0.3 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EIM82669.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EIM82669.1 - 0.1 11.9 0.1 0.1 11.9 0.1 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EIM82669.1 - 0.2 11.5 0.1 0.47 10.3 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pacifastin_I PF05375.13 EIM82669.1 - 0.54 10.0 4.7 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Tannase PF07519.11 EIM82670.1 - 7.8e-100 335.0 0.3 1e-99 334.6 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EIM82670.1 - 0.058 12.9 0.2 0.15 11.5 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EIM82670.1 - 0.068 12.4 0.0 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ssl1 PF04056.14 EIM82671.1 - 2.3e-69 233.1 0.0 3.5e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 EIM82671.1 - 5.7e-14 52.7 0.0 1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EIM82671.1 - 9e-05 22.1 5.9 0.28 10.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 Sec7 PF01369.20 EIM82672.1 - 3.6e-35 121.3 0.0 5.1e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 EIM82672.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 PH domain Cation_efflux PF01545.21 EIM82673.1 - 1.3e-44 152.3 0.0 3e-44 151.1 0.0 1.6 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EIM82673.1 - 6.3e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter EspG PF06872.11 EIM82673.1 - 0.02 13.5 0.2 0.03 12.9 0.2 1.1 1 0 0 1 1 1 0 EspG protein F-box-like PF12937.7 EIM82674.1 - 0.033 14.1 0.3 0.089 12.7 0.3 1.8 1 0 0 1 1 1 0 F-box-like RAI16-like PF10257.9 EIM82676.1 - 0.0071 15.3 0.0 0.0088 15.0 0.0 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF3213 PF11491.8 EIM82676.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) APH PF01636.23 EIM82678.1 - 1.4e-15 57.9 0.0 2.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM82678.1 - 0.00014 21.6 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EIM82678.1 - 0.0036 16.9 0.0 0.053 13.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 EIM82678.1 - 0.087 11.7 0.0 0.73 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.17 EIM82678.1 - 0.11 11.8 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase LPG_synthase_TM PF03706.13 EIM82679.1 - 0.07 12.7 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region KASH PF10541.9 EIM82679.1 - 0.28 11.5 0.2 0.28 11.5 0.2 2.4 2 0 0 2 2 2 0 Nuclear envelope localisation domain Dickkopf_N PF04706.12 EIM82679.1 - 1.7 9.2 36.6 0.095 13.2 10.9 4.0 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Peptidase_C14 PF00656.22 EIM82680.1 - 2e-19 70.5 0.0 3.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DnaJ PF00226.31 EIM82682.1 - 1.4e-09 37.9 0.1 3.3e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1771 PF08590.10 EIM82684.1 - 7.4e-18 64.7 5.5 7.4e-18 64.7 5.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EIM82684.1 - 1.5e-10 41.3 0.2 3.2e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 Smr domain Smr PF01713.21 EIM82685.1 - 6.6e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 EIM82685.1 - 0.00015 22.1 1.2 0.0004 20.7 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) F-box-like PF12937.7 EIM82687.1 - 1.1e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM82687.1 - 0.0024 17.7 0.2 2.8 7.9 0.1 2.8 2 0 0 2 2 2 2 F-box domain p450 PF00067.22 EIM82688.1 - 9e-67 225.8 0.0 1.2e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 EIM82689.1 - 3e-05 24.6 0.0 0.023 15.4 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EIM82689.1 - 0.055 14.1 0.0 0.7 10.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF1771 PF08590.10 EIM82690.1 - 7.6e-20 71.1 5.6 7.6e-20 71.1 5.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EIM82690.1 - 0.0023 18.2 0.1 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 EIM82692.1 - 1.1e-23 83.4 6.6 1.7e-23 82.7 5.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EIM82692.1 - 4.7e-12 46.1 0.2 1.5e-11 44.5 0.2 1.9 1 0 0 1 1 1 1 Smr domain Ribosomal_S5 PF00333.20 EIM82693.1 - 2.8e-28 97.7 0.6 2.8e-28 97.7 0.6 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EIM82693.1 - 1.9e-23 81.7 0.1 3.1e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EIM82693.1 - 0.98 10.0 13.4 1.8 9.1 13.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ODC_AZ PF02100.17 EIM82694.1 - 3.2e-13 49.7 0.0 5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme CN_hydrolase PF00795.22 EIM82695.1 - 2.4e-42 145.1 0.0 2.9e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RNA_pol_A_bac PF01000.26 EIM82696.1 - 3.1e-30 104.8 0.1 5.2e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EIM82696.1 - 2.8e-18 65.1 0.0 4.3e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain 6PF2K PF01591.18 EIM82696.1 - 0.028 13.7 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF22 PF01629.16 EIM82696.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 MS_channel PF00924.18 EIM82698.1 - 6.5e-12 45.4 9.7 4.6e-11 42.7 9.7 2.1 1 1 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EIM82698.1 - 0.0052 16.2 0.4 0.014 14.9 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EIM82698.1 - 0.015 15.1 1.3 0.027 14.4 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 EIM82698.1 - 0.037 13.5 0.1 0.076 12.5 0.1 1.5 1 0 0 1 1 1 0 EF hand Pkinase PF00069.25 EIM82699.1 - 7.5e-59 199.2 0.0 8.3e-38 130.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82699.1 - 5.1e-25 88.2 0.0 3.2e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIM82699.1 - 0.0028 17.6 0.6 0.0083 16.1 0.6 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM82699.1 - 0.0043 16.4 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIM82699.1 - 0.077 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EIM82699.1 - 0.095 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EIM82699.1 - 0.099 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 EIM82699.1 - 0.12 13.1 0.3 1.3 9.8 0.0 2.7 2 1 0 2 2 2 0 Protein kinase C terminal domain PBD PF00786.28 EIM82699.1 - 0.13 12.6 0.1 0.55 10.6 0.1 2.1 1 1 0 1 1 1 0 P21-Rho-binding domain Homeodomain PF00046.29 EIM82700.1 - 4.9e-16 58.3 3.5 4.9e-16 58.3 3.5 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EIM82700.1 - 0.00042 20.1 1.5 0.00075 19.3 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain ABC_tran PF00005.27 EIM82701.1 - 1e-47 162.1 0.7 2.5e-28 99.3 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EIM82701.1 - 4.9e-14 52.8 0.7 0.009 15.9 0.2 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIM82701.1 - 2.1e-11 43.7 0.0 0.00063 19.2 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EIM82701.1 - 4.4e-10 39.3 0.0 9.1e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EIM82701.1 - 3.7e-06 27.0 0.1 0.025 14.7 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EIM82701.1 - 4.6e-06 26.3 1.7 0.091 12.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EIM82701.1 - 5.4e-06 27.0 3.4 0.0083 16.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 EIM82701.1 - 1.5e-05 25.3 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EIM82701.1 - 3.5e-05 24.0 0.2 0.24 11.5 0.0 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_22 PF13401.6 EIM82701.1 - 4.9e-05 23.6 0.2 0.79 10.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EIM82701.1 - 6.6e-05 23.5 0.0 0.24 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EIM82701.1 - 0.00018 21.5 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EIM82701.1 - 0.00031 21.2 0.0 1.7 9.0 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain HEAT PF02985.22 EIM82701.1 - 0.00031 20.7 0.8 1.7 9.1 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat AAA_33 PF13671.6 EIM82701.1 - 0.00078 19.6 0.0 1.8 8.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EIM82701.1 - 0.00094 19.1 0.6 0.12 12.3 0.0 3.0 3 0 0 3 3 3 1 NACHT domain MeaB PF03308.16 EIM82701.1 - 0.0016 17.5 1.2 0.65 8.9 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EIM82701.1 - 0.0021 17.8 0.2 2.3 7.9 0.1 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EIM82701.1 - 0.0029 18.0 0.1 6.1 7.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 EIM82701.1 - 0.0082 16.2 0.1 3.9 7.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 EIM82701.1 - 0.016 15.4 0.0 10 6.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EIM82701.1 - 0.027 14.3 0.5 9.1 6.0 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 EIM82701.1 - 0.028 14.2 0.2 3.5 7.2 0.2 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 EIM82701.1 - 0.029 13.0 0.0 2.7 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain IFRD PF05004.13 EIM82701.1 - 0.03 13.4 0.2 0.17 11.0 0.2 2.0 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Dynamin_N PF00350.23 EIM82701.1 - 0.03 14.4 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 EIM82701.1 - 0.033 13.9 2.8 5.1 6.8 0.1 3.6 4 0 0 4 4 3 0 AAA domain AAA_7 PF12775.7 EIM82701.1 - 0.048 13.2 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 EIM82701.1 - 0.062 13.2 0.1 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATPase_2 PF01637.18 EIM82701.1 - 0.065 13.1 0.2 15 5.4 0.1 3.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea 4HB PF17947.1 EIM82701.1 - 0.12 12.5 0.0 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 Four helical bundle domain AAA PF00004.29 EIM82701.1 - 0.12 12.8 0.2 8.3 6.9 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EIM82701.1 - 0.13 11.8 0.5 20 4.7 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Tudor-knot PF11717.8 EIM82701.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Arf PF00025.21 EIM82701.1 - 0.14 11.6 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family NB-ARC PF00931.22 EIM82701.1 - 0.14 11.3 0.0 9.1 5.4 0.0 2.8 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 EIM82701.1 - 0.14 11.2 0.0 0.71 9.0 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 EIM82701.1 - 0.15 11.8 0.0 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT_EZ PF13513.6 EIM82701.1 - 0.19 12.3 3.6 1 9.9 0.4 3.3 3 1 1 4 4 2 0 HEAT-like repeat AAA_5 PF07728.14 EIM82701.1 - 0.61 10.1 1.9 41 4.2 0.1 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 EIM82701.1 - 0.62 7.5 2.7 4.1 4.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) p450 PF00067.22 EIM82702.1 - 8.4e-60 202.8 0.0 3e-59 201.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF443 PF04276.12 EIM82702.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF3149 PF11346.8 EIM82703.1 - 2.3 7.9 5.2 4.9 6.8 5.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) ABC1 PF03109.16 EIM82704.1 - 9.5e-35 119.3 0.0 1.6e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EIM82704.1 - 0.00023 20.8 0.1 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 RIO1 family RabGAP-TBC PF00566.18 EIM82705.1 - 9.7e-53 179.0 0.0 1.8e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CCDC144C PF14915.6 EIM82705.1 - 0.0019 17.4 5.5 0.0031 16.7 5.5 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region FAM184 PF15665.5 EIM82705.1 - 0.0088 15.8 2.4 0.015 15.1 2.4 1.4 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Scaffolding_pro PF11418.8 EIM82705.1 - 0.012 16.1 1.1 1.9 9.1 0.1 2.5 1 1 1 2 2 2 0 Phi29 scaffolding protein Cep57_CLD_2 PF14197.6 EIM82705.1 - 0.02 15.0 7.6 0.042 13.9 7.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 EIM82705.1 - 3 8.4 9.7 0.18 12.3 3.5 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region PC4 PF02229.16 EIM82706.1 - 5.7e-23 80.3 0.1 1e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) YscJ_FliF_C PF08345.11 EIM82706.1 - 0.0012 19.2 0.8 0.0017 18.7 0.8 1.3 1 1 0 1 1 1 1 Flagellar M-ring protein C-terminal TFIIE-A_C PF11521.8 EIM82706.1 - 0.0019 18.4 2.9 0.0032 17.7 2.9 1.3 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Pox_Ag35 PF03286.14 EIM82706.1 - 0.037 13.8 7.5 0.054 13.3 7.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pap_E4 PF02711.14 EIM82706.1 - 0.081 13.9 1.0 0.14 13.1 1.0 1.4 1 0 0 1 1 1 0 E4 protein FAM176 PF14851.6 EIM82706.1 - 0.67 9.6 2.9 0.84 9.3 2.9 1.3 1 0 0 1 1 1 0 FAM176 family DTHCT PF08070.11 EIM82706.1 - 4 8.2 20.0 7.7 7.3 20.0 1.5 1 1 0 1 1 1 0 DTHCT (NUC029) region DUF913 PF06025.12 EIM82707.1 - 5.7e-108 361.2 0.0 5.7e-108 361.2 0.0 5.7 4 1 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.25 EIM82707.1 - 5.1e-91 305.4 0.0 8.7e-91 304.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 EIM82707.1 - 1.6e-85 287.7 0.0 1.6e-85 287.7 0.0 3.9 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) UBM PF14377.6 EIM82707.1 - 4.5e-29 99.0 17.1 1.2e-10 40.4 0.5 4.1 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 EIM82707.1 - 2.6e-08 33.6 0.0 6.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF3361 PF11841.8 EIM82707.1 - 0.19 11.6 0.1 13 5.7 0.0 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Peptidase_C1_2 PF03051.15 EIM82709.1 - 4.5e-157 523.3 0.0 5.2e-157 523.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EIM82709.1 - 2.2e-08 34.5 0.0 0.0047 17.0 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease F-box PF00646.33 EIM82710.1 - 5.5e-05 22.9 0.9 0.00012 21.8 0.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM82710.1 - 0.09 12.7 3.3 0.073 13.0 0.8 2.1 2 0 0 2 2 2 0 F-box-like XhlA PF10779.9 EIM82711.1 - 0.002 18.3 3.6 0.02 15.1 0.3 3.1 3 0 0 3 3 3 1 Haemolysin XhlA Fib_alpha PF08702.10 EIM82711.1 - 0.019 15.1 5.6 2.6 8.2 0.2 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Sugarporin_N PF11471.8 EIM82711.1 - 0.021 14.8 1.4 0.021 14.8 1.4 2.3 2 0 0 2 2 1 0 Maltoporin periplasmic N-terminal extension OmpH PF03938.14 EIM82711.1 - 0.033 14.5 8.2 0.81 10.0 1.7 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PTRF_SDPR PF15237.6 EIM82711.1 - 0.046 13.4 0.8 0.096 12.3 0.8 1.5 1 0 0 1 1 1 0 PTRF/SDPR family YkyA PF10368.9 EIM82711.1 - 0.12 12.0 13.9 0.83 9.3 3.4 2.6 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein AAA_13 PF13166.6 EIM82711.1 - 0.25 9.9 8.8 0.56 8.8 8.8 1.5 1 1 0 1 1 1 0 AAA domain GAS PF13851.6 EIM82711.1 - 0.35 10.2 10.2 2.4 7.5 1.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 EIM82711.1 - 0.39 11.0 2.1 6.4 7.1 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ECM11 PF15463.6 EIM82711.1 - 0.72 10.4 3.9 2.3 8.8 0.1 2.8 2 1 0 2 2 2 0 Extracellular mutant protein 11 CHASE3 PF05227.13 EIM82711.1 - 0.86 9.5 5.7 5.9 6.8 0.3 2.6 2 0 0 2 2 2 0 CHASE3 domain KxDL PF10241.9 EIM82711.1 - 1.4 9.2 5.1 4 7.8 1.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Phage_GP20 PF06810.11 EIM82711.1 - 4.2 7.2 11.5 1.9 8.3 0.5 3.4 2 1 1 3 3 3 0 Phage minor structural protein GP20 Sec2p PF06428.11 EIM82711.1 - 5.3 7.1 10.3 0.45 10.5 1.9 3.0 2 2 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF1043 PF06295.12 EIM82711.1 - 8.5 6.4 10.5 0.57 10.2 2.8 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1043) TMPIT PF07851.13 EIM82711.1 - 9.7 5.3 6.3 1 8.5 1.1 1.8 2 0 0 2 2 2 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 EIM82711.1 - 10 6.8 8.9 8.1 7.1 0.6 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PARP PF00644.20 EIM82712.1 - 3.9e-15 56.0 0.0 7.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF5338 PF17273.2 EIM82712.1 - 0.0017 18.4 1.9 0.7 10.0 0.0 3.4 3 0 0 3 3 3 1 Family of unknown function (DUF5338) PAP_central PF04928.17 EIM82712.1 - 0.0098 14.9 0.2 0.016 14.2 0.2 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain TPR_1 PF00515.28 EIM82713.1 - 8.6e-10 38.0 7.6 3.6e-07 29.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM82713.1 - 4.4e-06 26.4 13.5 5.5e-06 26.1 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM82713.1 - 0.00047 20.7 6.6 0.45 11.2 0.6 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EIM82713.1 - 0.003 17.6 1.5 0.025 14.7 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM82713.1 - 0.0089 16.2 0.1 0.0089 16.2 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82713.1 - 0.012 16.3 0.7 0.012 16.3 0.7 3.4 3 2 1 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82713.1 - 0.015 15.5 4.4 0.019 15.2 2.6 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM82713.1 - 0.044 13.5 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 EIM82713.1 - 0.048 14.3 0.8 0.048 14.3 0.8 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIM82713.1 - 0.077 13.5 4.0 1.6 9.3 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat UIM PF02809.20 EIM82713.1 - 0.17 11.8 0.5 0.17 11.8 0.5 2.6 3 0 0 3 3 3 0 Ubiquitin interaction motif TPR_7 PF13176.6 EIM82713.1 - 5 7.4 5.5 1.9 8.7 0.1 2.8 4 0 0 4 4 3 0 Tetratricopeptide repeat p450 PF00067.22 EIM82714.1 - 3.3e-60 204.1 0.0 4.3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2070 PF09843.9 EIM82714.1 - 0.12 10.7 2.1 0.17 10.1 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AAA_lid_2 PF17863.1 EIM82715.1 - 0.073 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 AAA lid domain Glyco_hydro_18 PF00704.28 EIM82717.1 - 8.2e-83 278.7 0.2 1.1e-82 278.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_transf_8 PF01501.20 EIM82719.1 - 5.6e-21 75.3 0.0 1.7e-20 73.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 EIM82719.1 - 3.1e-15 57.1 0.1 1.7e-14 54.7 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_24 PF18404.1 EIM82719.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Amidohydro_1 PF01979.20 EIM82721.1 - 1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM82721.1 - 3.4e-08 33.4 0.0 4.5e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family NTP_transf_2 PF01909.23 EIM82721.1 - 0.031 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain ChAPs PF09295.10 EIM82722.1 - 0.0039 16.2 0.5 0.97 8.4 0.0 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 EIM82722.1 - 0.009 16.1 0.9 0.029 14.5 0.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM82722.1 - 0.0097 16.4 1.7 0.0097 16.4 1.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Shadoo PF14999.6 EIM82722.1 - 0.017 15.3 1.2 0.022 14.9 1.2 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TPR_2 PF07719.17 EIM82722.1 - 0.064 13.4 2.8 25 5.3 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIM82722.1 - 0.24 12.1 7.8 0.077 13.7 4.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82722.1 - 2.1 9.4 8.3 5.5 8.1 2.1 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM82723.1 - 3.7e-28 95.4 20.9 0.0061 16.6 0.0 16.8 20 0 0 20 20 17 6 Tetratricopeptide repeat TPR_1 PF00515.28 EIM82723.1 - 1e-25 88.4 6.5 0.00074 19.2 0.1 12.9 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 EIM82723.1 - 2.7e-25 88.7 15.2 0.00021 21.7 0.0 11.1 9 2 2 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 EIM82723.1 - 6.2e-24 82.6 13.6 0.011 16.0 0.6 12.1 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_16 PF13432.6 EIM82723.1 - 9.7e-21 74.1 26.3 7.3e-07 29.7 0.2 10.5 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82723.1 - 1.2e-19 69.3 23.9 0.00055 20.5 0.0 14.6 12 5 6 18 18 16 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIM82723.1 - 2.8e-19 68.5 1.8 4.9e-05 22.9 0.3 9.8 11 0 0 11 11 11 3 TPR repeat TPR_8 PF13181.6 EIM82723.1 - 7.1e-19 66.4 17.3 0.0071 16.5 0.0 14.6 17 0 0 17 17 17 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIM82723.1 - 1.8e-12 46.3 3.4 3.1 8.0 0.0 9.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82723.1 - 2.8e-10 40.3 28.9 0.02 15.1 0.0 12.3 12 3 3 15 15 15 2 Tetratricopeptide repeat TPR_9 PF13371.6 EIM82723.1 - 8.4e-10 38.7 19.1 0.011 15.8 0.1 8.9 8 2 2 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM82723.1 - 1.9e-09 37.6 3.9 0.055 13.7 0.1 7.5 6 1 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EIM82723.1 - 4.7e-07 30.0 22.1 1.7 9.4 0.0 11.2 13 1 0 13 13 12 1 Tetratricopeptide repeat TPR_20 PF14561.6 EIM82723.1 - 0.00021 21.6 2.7 0.4 11.1 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_22 PF18833.1 EIM82723.1 - 0.038 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EIM82723.1 - 0.058 12.4 0.5 2.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Coatomer WD associated region Methyltransf_11 PF08241.12 EIM82723.1 - 0.15 12.7 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPR_10 PF13374.6 EIM82723.1 - 0.92 9.5 13.9 14 5.7 0.1 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.20 EIM82724.1 - 4.9e-24 85.3 0.0 1.6e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 EIM82724.1 - 2.5e-16 60.6 0.0 5.8e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Glyco_transf_24 PF18404.1 EIM82724.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 Epimerase PF01370.21 EIM82725.1 - 3.2e-39 134.9 0.0 4.9e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM82725.1 - 2.8e-19 69.7 0.0 4.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glycos_transf_2 PF00535.26 EIM82725.1 - 1.1e-17 64.4 0.3 3e-16 59.7 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 2 3Beta_HSD PF01073.19 EIM82725.1 - 6.2e-17 61.5 0.0 9.8e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM82725.1 - 4.9e-09 36.3 0.0 8.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tranf_2_2 PF10111.9 EIM82725.1 - 1e-06 28.4 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EIM82725.1 - 3.3e-06 27.2 0.0 1e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NAD_binding_4 PF07993.12 EIM82725.1 - 0.0002 20.6 0.0 0.039 13.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EIM82725.1 - 0.00053 19.2 0.0 0.13 11.4 0.0 2.9 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EIM82725.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 EIM82725.1 - 0.0029 17.8 0.0 0.0096 16.2 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Gluconate_2-dh3 PF13618.6 EIM82725.1 - 0.048 13.9 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 KR PF08659.10 EIM82725.1 - 0.052 13.5 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 EIM82725.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 EIM82725.1 - 0.12 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase LETM1 PF07766.13 EIM82728.1 - 4.4e-34 118.0 0.8 1.1e-17 64.3 0.2 2.1 1 1 1 2 2 2 2 LETM1-like protein p450 PF00067.22 EIM82729.1 - 1.2e-74 251.7 0.0 1.9e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GYF_2 PF14237.6 EIM82729.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 GYF domain 2 Cas_NE0113 PF09623.10 EIM82729.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) YesK PF14150.6 EIM82730.1 - 0.0081 16.3 1.7 0.0081 16.3 1.7 2.7 3 1 0 3 3 3 1 YesK-like protein DUF624 PF04854.14 EIM82730.1 - 3.8 7.7 7.2 13 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF624 Peptidase_M14 PF00246.24 EIM82731.1 - 9.7e-18 65.0 0.0 2e-17 63.9 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EIM82731.1 - 0.00029 20.0 0.4 0.00045 19.4 0.4 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PPO1_DWL PF12142.8 EIM82731.1 - 0.049 13.4 1.2 0.12 12.2 1.2 1.6 1 0 0 1 1 1 0 Polyphenol oxidase middle domain TPR_2 PF07719.17 EIM82732.1 - 2.5e-11 42.8 5.4 0.00013 21.8 0.6 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIM82732.1 - 3.5e-10 39.2 4.9 0.00015 21.4 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM82732.1 - 2.2e-07 31.4 6.0 2.2e-07 31.4 6.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM82732.1 - 2.2e-06 27.4 2.3 0.0062 16.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82732.1 - 0.00014 22.4 13.0 0.0019 18.8 2.5 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82732.1 - 0.00043 20.5 4.9 0.35 11.2 0.5 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM82732.1 - 0.0018 18.7 6.7 0.0052 17.3 3.7 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM82732.1 - 0.0028 17.8 0.5 0.011 16.0 0.5 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EIM82732.1 - 0.003 17.7 2.2 0.039 14.1 1.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM82732.1 - 0.007 16.3 1.8 3.2 8.0 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EIM82732.1 - 0.053 12.9 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_17 PF13431.6 EIM82732.1 - 0.056 13.8 6.2 0.11 13.0 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2610 PF11020.8 EIM82732.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) AAA_PrkA PF08298.11 EIM82732.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain TPR_6 PF13174.6 EIM82732.1 - 1.3 9.8 8.9 0.43 11.3 0.5 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Aa_trans PF01490.18 EIM82733.1 - 6.5e-64 216.1 31.5 9.9e-64 215.5 31.5 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Saf_2TM PF18303.1 EIM82733.1 - 0.2 11.2 3.2 7.5 6.1 0.0 3.4 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain tRNA-synt_1 PF00133.22 EIM82734.1 - 3e-222 739.2 0.0 1.2e-221 737.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EIM82734.1 - 8.8e-27 93.9 0.1 1.8e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EIM82734.1 - 1.6e-13 50.2 0.9 0.0001 21.2 0.2 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EIM82734.1 - 0.028 13.8 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain EXS PF03124.14 EIM82735.1 - 6.5e-94 314.9 0.0 4.3e-92 309.0 0.0 2.0 1 1 0 1 1 1 1 EXS family CHDCT2 PF08074.11 EIM82735.1 - 0.062 13.5 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain GHMP_kinases_N PF00288.26 EIM82736.1 - 2.4e-12 46.9 2.4 5.2e-12 45.8 2.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EIM82736.1 - 1.7e-06 28.3 0.0 5.7e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal Phage_AlpA PF05930.12 EIM82737.1 - 0.17 11.7 0.4 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) CPSase_sm_chain PF00988.22 EIM82738.1 - 1.6e-44 150.8 0.0 2.5e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EIM82738.1 - 1.1e-35 123.1 0.0 1.6e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIM82738.1 - 2.8e-08 33.8 0.1 5.8e-07 29.5 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EIM82738.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Metallophos PF00149.28 EIM82739.1 - 3.6e-15 57.0 0.1 5.1e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.26 EIM82740.1 - 2e-19 69.8 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM82740.1 - 4.6e-16 58.7 0.0 1.2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EIM82740.1 - 0.00012 23.1 0.0 0.00022 22.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EIM82741.1 - 1.3e-19 70.5 0.0 2.2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM82741.1 - 4.2e-18 65.2 0.0 9e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EIM82741.1 - 2.9e-07 31.6 0.0 4.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BAG PF02179.16 EIM82742.1 - 2e-18 66.6 0.0 4.8e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EIM82742.1 - 4e-08 32.9 0.0 1.2e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Pkinase PF00069.25 EIM82743.1 - 2.3e-55 187.8 0.0 3e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82743.1 - 5.8e-36 124.1 0.0 7.8e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM82743.1 - 5.1e-07 29.3 0.0 7.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIM82743.1 - 0.0028 16.5 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EIM82743.1 - 0.005 15.8 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIM82743.1 - 0.0075 16.2 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EIM82743.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4807 PF16065.5 EIM82744.1 - 0.019 14.7 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Sulfotransfer_4 PF17784.1 EIM82744.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain TLV_coat PF00429.19 EIM82745.1 - 0.17 10.6 0.1 0.21 10.2 0.1 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) RVT_3 PF13456.6 EIM82746.1 - 0.048 13.5 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase-like CclA_1 PF16942.5 EIM82748.1 - 0.29 11.4 4.4 0.13 12.5 0.5 2.3 2 0 0 2 2 2 0 Putative cyclic bacteriocin ADH_zinc_N PF00107.26 EIM82750.1 - 2.2e-20 72.9 0.0 3.3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM82750.1 - 1.2e-12 47.7 0.0 2.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EIM82750.1 - 7.6e-05 23.8 0.0 0.00018 22.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 EIM82750.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HMG_box PF00505.19 EIM82751.1 - 8.2e-06 26.1 0.2 3.9e-05 24.0 0.2 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM82751.1 - 0.12 13.0 0.4 0.42 11.2 0.4 1.8 1 1 0 1 1 1 0 HMG-box domain F-box PF00646.33 EIM82753.1 - 1.3e-06 28.1 0.0 2.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM82753.1 - 0.00031 20.6 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like Glyco_hydro_92 PF07971.12 EIM82754.1 - 1.1e-117 393.8 0.4 1.3e-117 393.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EIM82754.1 - 2.4e-50 171.7 0.0 4.4e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Smr PF01713.21 EIM82756.1 - 8.4e-06 26.1 0.2 1e-05 25.8 0.2 1.1 1 0 0 1 1 1 1 Smr domain DDE_Tnp_1_4 PF13701.6 EIM82757.1 - 0.23 9.7 0.0 0.3 9.3 0.0 1.0 1 0 0 1 1 1 0 Transposase DDE domain group 1 FAM195 PF14799.6 EIM82758.1 - 2.1e-05 24.8 0.2 0.033 14.5 0.0 2.3 1 1 1 2 2 2 2 FAM195 family Radial_spoke PF04712.12 EIM82758.1 - 0.0082 15.1 0.3 0.017 14.1 0.1 1.5 1 1 1 2 2 2 1 Radial spokehead-like protein ATPase_2 PF01637.18 EIM82758.1 - 0.014 15.4 0.0 1.9 8.3 0.0 2.1 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF4208 PF13907.6 EIM82758.1 - 0.037 14.4 0.1 5.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Cyclase_polyket PF04673.12 EIM82758.1 - 0.053 13.8 0.9 6.9 7.0 0.1 2.2 2 0 0 2 2 2 0 Polyketide synthesis cyclase DUF4570 PF15134.6 EIM82758.1 - 0.17 11.9 1.7 4.6 7.3 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) Pkinase PF00069.25 EIM82760.1 - 7.6e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EIM82760.1 - 0.00031 20.2 0.1 0.00092 18.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EIM82760.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pept_tRNA_hydro PF01195.19 EIM82761.1 - 9.1e-37 126.6 0.0 1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase HlyIII PF03006.20 EIM82762.1 - 9.9e-37 126.8 20.2 1.4e-36 126.4 19.8 1.4 2 0 0 2 2 2 1 Haemolysin-III related Mucin PF01456.17 EIM82762.1 - 0.25 11.3 10.0 0.5 10.3 10.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1691 PF07950.11 EIM82762.1 - 0.27 12.0 1.9 0.45 11.3 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1691) TFIID_20kDa PF03847.13 EIM82763.1 - 1.5e-28 99.1 0.1 3.1e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EIM82763.1 - 0.00071 19.8 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Loricrin PF15847.5 EIM82763.1 - 0.0043 16.2 19.2 0.0043 16.2 19.2 1.6 2 0 0 2 2 2 1 Major keratinocyte cell envelope protein TFIID-31kDa PF02291.15 EIM82763.1 - 0.012 15.7 0.0 0.041 14.0 0.0 1.8 2 1 1 3 3 3 0 Transcription initiation factor IID, 31kD subunit TFIIA PF03153.13 EIM82763.1 - 0.032 14.3 22.8 0.044 13.8 22.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 EIM82763.1 - 0.047 14.1 1.2 0.31 11.4 0.0 2.4 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIM82763.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Roughex PF06020.11 EIM82763.1 - 5.3 6.0 6.3 8 5.5 6.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein AFG1_ATPase PF03969.16 EIM82765.1 - 2e-51 175.0 0.0 6.7e-46 156.8 0.0 3.2 3 1 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 EIM82765.1 - 2.9e-08 34.3 0.0 1e-07 32.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EIM82765.1 - 2.5e-05 24.7 0.0 5.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIM82765.1 - 0.00017 21.9 0.0 0.016 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EIM82765.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EIM82765.1 - 0.012 15.3 0.0 5.2 6.8 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EIM82765.1 - 0.068 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EIM82765.1 - 0.1 12.3 0.0 7.1 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EIM82765.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EIM82765.1 - 0.17 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EIM82765.1 - 0.21 11.5 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EIM82765.1 - 0.22 11.0 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HSP20 PF00011.21 EIM82767.1 - 0.0016 18.6 0.0 0.021 15.0 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family SVM_signal PF12113.8 EIM82768.1 - 0.41 10.6 1.7 6.7 6.7 0.0 2.2 2 0 0 2 2 2 0 SVM protein signal sequence Git3 PF11710.8 EIM82772.1 - 2.6e-12 47.0 5.9 6.6e-12 45.6 5.9 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF2788 PF10981.8 EIM82772.1 - 1.4 9.0 8.1 6.2 6.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2788) DUF2304 PF10066.9 EIM82772.1 - 2.8 8.2 10.3 22 5.3 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF3669 PF12417.8 EIM82773.1 - 6.9e-09 35.8 0.4 1.3e-08 34.9 0.4 1.4 1 0 0 1 1 1 1 Zinc finger protein DUF4159 PF13709.6 EIM82773.1 - 0.038 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Ribosomal_L39 PF00832.20 EIM82775.1 - 9.6e-23 79.5 9.9 1.2e-22 79.3 9.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 EIM82775.1 - 0.045 13.3 0.2 0.045 13.3 0.2 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 FKBP_C PF00254.28 EIM82776.1 - 1.6e-32 111.7 0.0 2e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nkap_C PF06047.11 EIM82777.1 - 1.6e-40 137.3 3.9 1.6e-40 137.3 3.9 2.9 2 1 1 3 3 3 1 NF-kappa-B-activating protein C-terminal domain Pkinase PF00069.25 EIM82778.1 - 2.2e-19 69.8 0.0 4.7e-19 68.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82778.1 - 3.1e-13 49.6 0.0 1.6e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EIM82778.1 - 8.2e-06 25.5 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM82778.1 - 0.0044 17.0 0.1 0.018 15.0 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM82778.1 - 0.02 14.3 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EIM82779.1 - 7.8e-48 163.1 0.0 1.3e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82779.1 - 2.9e-28 98.9 0.0 3.9e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM82779.1 - 9.7e-05 21.8 0.0 0.0002 20.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIM82779.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM82779.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Papilin_u7 PF16626.5 EIM82780.1 - 0.37 11.4 0.2 0.37 11.4 0.2 2.6 2 1 0 2 2 2 0 Linking region between Kunitz_BPTI and I-set on papilin MDM10 PF12519.8 EIM82780.1 - 0.38 9.5 5.3 0.5 9.2 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 HMG_box PF00505.19 EIM82781.1 - 0.0024 18.2 0.9 0.011 16.1 0.9 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 EIM82781.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Malate_synthase PF01274.22 EIM82782.1 - 2.7e-199 662.8 0.0 3.3e-199 662.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EIM82782.1 - 0.013 14.6 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family CHD5 PF04420.14 EIM82783.1 - 6.9e-57 191.8 3.9 9.4e-57 191.3 3.9 1.2 1 0 0 1 1 1 1 CHD5-like protein BHD_2 PF10404.9 EIM82783.1 - 0.0069 17.3 0.1 0.71 10.9 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 KxDL PF10241.9 EIM82783.1 - 0.17 12.2 2.6 0.3 11.4 2.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein HMG_box PF00505.19 EIM82784.1 - 4.5e-07 30.2 5.7 1e-06 29.1 5.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM82784.1 - 0.0022 18.5 2.3 0.0022 18.5 2.3 1.9 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EIM82786.1 - 1.7e-12 47.6 0.0 2.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM82786.1 - 0.00054 20.5 1.1 0.00064 20.3 1.1 1.3 1 1 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EIM82787.1 - 2.9e-07 30.8 4.6 2.9e-07 30.8 4.6 2.0 2 1 0 2 2 2 1 HMG (high mobility group) box Rab_eff_C PF04698.12 EIM82787.1 - 0.23 9.7 0.9 0.31 9.3 0.9 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus ATP-synt_DE_N PF02823.16 EIM82788.1 - 1.8e-17 63.0 0.0 2.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Peptidase_S64 PF08192.11 EIM82789.1 - 0.002 16.7 0.5 0.0029 16.2 0.4 1.3 1 1 0 1 1 1 1 Peptidase family S64 OsmC PF02566.19 EIM82790.1 - 3.4e-14 53.1 0.0 5.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein 2OG-FeII_Oxy_2 PF13532.6 EIM82791.1 - 1.8e-16 60.9 0.1 3.3e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EIM82792.1 - 0.00012 21.6 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82792.1 - 0.081 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Homeodomain PF00046.29 EIM82794.1 - 7.1e-18 64.2 1.9 1.3e-17 63.3 1.9 1.5 1 0 0 1 1 1 1 Homeodomain zf-TRAF PF02176.18 EIM82795.1 - 1.6e-08 35.1 17.3 0.0013 19.4 4.1 4.1 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 EIM82795.1 - 4.5e-07 29.6 12.4 4.5e-07 29.6 12.4 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EIM82795.1 - 9.2e-06 25.4 6.9 9.2e-06 25.4 6.9 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 EIM82795.1 - 1.1e-05 25.6 11.8 1.1e-05 25.6 11.8 3.8 2 1 2 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM82795.1 - 2.2e-05 24.4 12.0 2.2e-05 24.4 12.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 EIM82795.1 - 0.00018 21.9 25.0 0.0046 17.4 6.0 3.5 1 1 2 3 3 3 1 TRAF-like zinc-finger zf-C3HC4 PF00097.25 EIM82795.1 - 0.00018 21.3 12.3 0.00018 21.3 12.3 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM82795.1 - 0.0013 18.6 11.0 0.0013 18.6 11.0 3.5 3 2 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIM82795.1 - 0.0056 16.5 8.5 0.0056 16.5 8.5 4.2 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) GIT_CC PF16559.5 EIM82795.1 - 0.0061 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor zf-ACC PF17848.1 EIM82795.1 - 0.03 14.4 4.1 0.73 10.0 0.4 3.3 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Sina PF03145.16 EIM82795.1 - 0.16 11.9 13.0 0.22 11.4 0.8 2.8 1 1 2 3 3 3 0 Seven in absentia protein family zf-RING_6 PF14835.6 EIM82795.1 - 4.7 7.2 12.2 0.047 13.6 3.6 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DEAD PF00270.29 EIM82796.1 - 3.1e-39 134.5 0.0 4.9e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EIM82796.1 - 3.3e-20 72.0 0.1 7.1e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EIM82796.1 - 1.5e-16 60.7 0.0 5.3e-15 55.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM82796.1 - 0.00017 21.6 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FAM176 PF14851.6 EIM82796.1 - 0.052 13.2 2.2 0.53 9.9 0.1 2.3 2 0 0 2 2 2 0 FAM176 family Laminin_I PF06008.14 EIM82798.1 - 0.0023 17.7 5.1 0.0023 17.7 5.1 1.7 1 1 0 1 1 1 1 Laminin Domain I Mt_ATP_synt PF15704.5 EIM82798.1 - 0.0077 16.1 2.1 0.011 15.6 0.3 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase subunit Spc7 PF08317.11 EIM82798.1 - 0.011 14.7 12.9 0.024 13.5 12.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EIM82798.1 - 0.022 14.8 0.6 0.022 14.8 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.21 EIM82798.1 - 0.048 14.2 9.5 1.2 9.6 3.8 3.2 2 1 0 3 3 3 0 Spectrin repeat MscS_porin PF12795.7 EIM82798.1 - 0.052 13.1 12.6 0.088 12.3 12.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 EIM82798.1 - 0.07 12.5 8.7 0.12 11.7 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1759 PF03564.15 EIM82798.1 - 0.2 11.6 1.1 0.38 10.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Atg14 PF10186.9 EIM82798.1 - 0.27 10.3 13.8 12 4.9 0.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 EIM82798.1 - 0.37 11.4 14.6 0.4 11.3 0.7 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 EIM82798.1 - 0.47 11.1 5.2 0.23 12.1 1.9 2.2 1 1 0 2 2 2 0 SlyX FliJ PF02050.16 EIM82798.1 - 0.62 10.3 11.2 0.027 14.7 3.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein FAM76 PF16046.5 EIM82798.1 - 0.94 8.8 9.0 1.5 8.1 9.0 1.2 1 0 0 1 1 1 0 FAM76 protein IFT57 PF10498.9 EIM82798.1 - 1.2 8.1 9.0 1.8 7.4 9.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HAUS-augmin3 PF14932.6 EIM82798.1 - 4.4 6.8 10.5 6 6.4 10.1 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 EIM82798.1 - 7 6.8 22.0 3.9 7.6 8.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 EIM82798.1 - 7.1 6.7 7.4 1.9 8.5 0.5 3.0 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 EIM82798.1 - 7.5 6.6 11.6 1.6 8.8 1.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EIM82798.1 - 7.8 6.6 8.2 4.2 7.4 4.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EIM82799.1 - 0.011 16.0 4.0 0.026 14.8 4.0 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CHASE3 PF05227.13 EIM82799.1 - 0.024 14.6 5.8 0.43 10.5 2.8 2.4 2 0 0 2 2 2 0 CHASE3 domain CHDCT2 PF08074.11 EIM82799.1 - 0.065 13.4 1.0 0.18 12.0 0.3 1.9 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Bax1-I PF01027.20 EIM82801.1 - 2.9e-50 171.0 21.8 3.4e-50 170.8 21.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 EIM82801.1 - 0.0045 16.6 13.5 0.02 14.5 13.5 2.0 1 1 0 1 1 1 1 Bax inhibitor 1 like CMAS PF02353.20 EIM82804.1 - 5.5e-32 111.2 0.1 9.2e-31 107.1 0.1 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EIM82804.1 - 1.6e-13 51.2 0.0 3.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM82804.1 - 5.5e-13 49.4 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM82804.1 - 1.9e-10 40.8 0.0 3.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM82804.1 - 6.1e-10 39.2 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM82804.1 - 1.7e-09 38.3 0.0 3.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM82804.1 - 6.6e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EIM82804.1 - 2.2e-05 24.0 0.0 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EIM82804.1 - 0.00021 20.8 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 EIM82804.1 - 0.0036 16.9 0.0 0.0084 15.7 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 EIM82804.1 - 0.0049 16.5 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F tRNA_U5-meth_tr PF05958.11 EIM82804.1 - 0.0066 15.5 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.19 EIM82804.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EIM82804.1 - 0.04 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 EIM82804.1 - 0.092 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.18 EIM82804.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pro-kuma_activ PF09286.11 EIM82805.1 - 1.6e-45 154.9 0.0 4.3e-45 153.5 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM82805.1 - 0.013 14.7 3.4 0.027 13.8 3.4 1.4 1 0 0 1 1 1 0 Subtilase family Adenyl_cycl_N PF12633.7 EIM82805.1 - 0.061 13.2 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase NT domain CFEM PF05730.11 EIM82806.1 - 1.7e-07 31.2 9.5 2.3e-07 30.8 9.5 1.2 1 0 0 1 1 1 1 CFEM domain DUF4006 PF13179.6 EIM82806.1 - 0.035 14.0 0.2 0.046 13.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PNISR PF15996.5 EIM82807.1 - 0.0044 17.3 13.9 0.0065 16.8 13.9 1.2 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR Cwf_Cwc_15 PF04889.12 EIM82807.1 - 0.75 9.5 22.4 1.2 8.8 22.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4746 PF15928.5 EIM82807.1 - 0.84 9.0 4.9 1.2 8.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BUD22 PF09073.10 EIM82807.1 - 2.1 7.6 21.0 3.2 7.0 21.0 1.2 1 0 0 1 1 1 0 BUD22 Occludin_ELL PF07303.13 EIM82808.1 - 0.0037 18.0 2.6 0.015 16.0 2.6 2.0 1 0 0 1 1 1 1 Occludin homology domain Epimerase PF01370.21 EIM82810.1 - 2.7e-18 66.3 0.1 4.6e-18 65.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM82810.1 - 6.1e-14 51.7 0.0 8.9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM82810.1 - 1.6e-11 43.9 0.0 3.5e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIM82810.1 - 1.8e-11 44.1 0.0 2.9e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM82810.1 - 3.9e-10 39.9 0.3 1.6e-09 37.9 0.3 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EIM82810.1 - 1e-05 25.2 0.2 1.9e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EIM82810.1 - 4.2e-05 23.5 0.4 0.0001 22.3 0.4 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EIM82810.1 - 0.00095 18.7 0.2 0.012 15.1 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase MDM31_MDM32 PF08118.11 EIM82811.1 - 4e-201 669.3 0.0 4.6e-201 669.1 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Cupin_5 PF06172.11 EIM82812.1 - 5.9e-42 143.2 0.0 7.5e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) SpoVIF PF14069.6 EIM82812.1 - 0.079 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Stage VI sporulation protein F FAT PF02259.23 EIM82813.1 - 4.9e-61 206.9 8.6 1.1e-60 205.8 8.6 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EIM82813.1 - 6.2e-23 81.9 0.0 1.4e-22 80.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EIM82813.1 - 0.0063 16.3 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain Spt20 PF12090.8 EIM82813.1 - 0.17 11.5 2.4 0.32 10.6 2.4 1.4 1 0 0 1 1 1 0 Spt20 family TPR_2 PF07719.17 EIM82813.1 - 0.21 11.8 0.7 29 5.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat KTI12 PF08433.10 EIM82814.1 - 4.2e-82 275.7 0.0 4.7e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EIM82814.1 - 2e-07 31.3 0.0 5.8e-07 29.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIM82814.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain RhoGAP PF00620.27 EIM82815.1 - 2.3e-43 147.6 0.1 6.4e-43 146.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EIM82815.1 - 3.3e-13 49.6 21.7 3.6e-08 33.5 3.0 3.0 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 EIM82815.1 - 4.9e-06 26.3 7.4 4.9e-06 26.3 7.4 4.1 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EIM82815.1 - 0.0042 17.4 1.2 0.0042 17.4 1.2 4.1 2 1 1 3 3 3 1 C1 domain Suppressor_APC PF11414.8 EIM82815.1 - 0.19 11.8 0.8 0.69 10.0 0.1 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein YabA PF06156.13 EIM82815.1 - 5.1 7.8 7.6 5.5 7.7 0.3 3.6 3 1 1 4 4 4 0 Initiation control protein YabA Chitin_synth_1 PF01644.17 EIM82816.1 - 2.7e-75 251.8 0.1 4.7e-75 251.0 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIM82816.1 - 6.5e-27 93.3 0.0 1.8e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIM82816.1 - 6.1e-23 81.2 6.2 1.9e-18 66.4 0.0 2.1 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIM82816.1 - 1.5e-09 38.1 0.3 1.5e-09 38.1 0.3 3.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF1218 PF06749.12 EIM82816.1 - 0.7 10.4 9.1 0.077 13.5 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) SLATT_fungal PF18142.1 EIM82816.1 - 1.1 9.2 3.0 0.64 10.0 0.5 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Herpes_LMP1 PF05297.11 EIM82816.1 - 9.1 5.4 8.3 16 4.5 8.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Aa_trans PF01490.18 EIM82819.1 - 4.2e-33 114.6 35.2 5.1e-33 114.4 35.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BTB PF00651.31 EIM82820.1 - 1.8e-12 47.5 0.0 3.1e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain PALP PF00291.25 EIM82821.1 - 2.6e-70 237.1 0.4 3e-70 237.0 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.21 EIM82822.1 - 5.1e-77 257.2 0.0 5.8e-77 257.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EIM82822.1 - 1.8e-15 57.2 0.1 2.5e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIM82822.1 - 4.6e-13 49.1 0.0 4.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EIM82822.1 - 8.1e-12 44.9 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EIM82822.1 - 1.9e-11 43.8 1.4 3.5e-07 29.7 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EIM82822.1 - 1.7e-09 37.4 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIM82822.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EIM82822.1 - 0.017 14.4 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase LRR_8 PF13855.6 EIM82824.1 - 1.1e-11 44.3 25.9 2.5e-07 30.4 8.6 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EIM82824.1 - 2.3e-11 43.7 17.9 1.6e-05 25.1 5.1 4.7 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EIM82824.1 - 0.0024 17.4 0.5 0.16 11.4 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EIM82824.1 - 0.097 13.3 16.6 5 8.1 0.4 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 EIM82824.1 - 0.47 10.6 16.1 3.4 8.0 1.0 5.4 5 0 0 5 5 5 0 Leucine Rich repeat Caleosin PF05042.13 EIM82825.1 - 1.2e-14 54.6 0.1 2e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Caleosin related protein EF-hand_8 PF13833.6 EIM82825.1 - 0.14 12.0 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain pair NCBP3 PF10309.9 EIM82825.1 - 0.18 11.7 0.2 0.33 10.8 0.2 1.4 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 UBA PF00627.31 EIM82826.1 - 2.3e-31 107.2 3.2 3.8e-15 55.4 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EIM82826.1 - 1.4e-22 79.2 0.9 2.4e-22 78.4 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 EIM82826.1 - 2.9e-21 74.9 11.1 2.9e-21 74.9 11.1 1.9 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 EIM82826.1 - 3.3e-07 30.0 1.5 5.2e-07 29.4 1.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EIM82826.1 - 0.0023 17.7 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 EIM82826.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1421 PF07223.11 EIM82826.1 - 0.057 13.3 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Ubiquitin_5 PF18037.1 EIM82826.1 - 0.072 13.5 0.3 0.13 12.7 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EIM82826.1 - 0.073 13.5 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TFIIA PF03153.13 EIM82826.1 - 1.5 8.8 11.7 2.2 8.2 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EIM82826.1 - 2.6 8.7 14.6 1.8 9.2 1.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5082 PF16888.5 EIM82827.1 - 0.002 18.4 8.3 0.002 18.4 8.3 4.9 3 1 0 3 3 3 1 Domain of unknown function (DUF5082) Filament PF00038.21 EIM82827.1 - 0.0098 15.5 13.5 0.0098 15.5 13.5 6.2 1 1 4 5 5 5 1 Intermediate filament protein Phage_GP20 PF06810.11 EIM82827.1 - 0.011 15.5 7.1 0.011 15.5 7.1 5.4 2 2 3 5 5 5 0 Phage minor structural protein GP20 GIT_CC PF16559.5 EIM82827.1 - 0.018 14.9 2.5 0.018 14.9 2.5 4.8 7 0 0 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 EIM82827.1 - 1.9 7.8 70.9 0.017 14.4 4.0 5.7 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding YojJ PF10372.9 EIM82827.1 - 2.7 8.2 5.9 30 4.8 0.1 4.1 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus PPR_2 PF13041.6 EIM82828.1 - 1.1e-31 108.7 0.0 1.4e-07 31.6 0.0 6.9 6 1 1 7 7 7 6 PPR repeat family PPR_3 PF13812.6 EIM82828.1 - 1.8e-27 95.2 0.0 5.4e-08 32.8 0.0 5.7 4 1 2 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 EIM82828.1 - 4.6e-15 55.0 0.5 0.079 12.7 0.0 6.3 6 0 0 6 6 6 4 PPR repeat PPR PF01535.20 EIM82828.1 - 8.5e-15 53.9 3.1 0.016 15.5 0.2 7.5 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 EIM82828.1 - 4.4e-14 52.4 0.0 0.00046 19.6 0.0 3.9 2 2 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP Exog_C PF18026.1 EIM82828.1 - 0.19 11.8 0.4 4.7 7.4 0.1 3.3 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain Rad21_Rec8_N PF04825.13 EIM82829.1 - 7.2e-37 125.9 0.1 1.2e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EIM82829.1 - 6.7e-14 50.9 0.0 1.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein CMD PF02627.20 EIM82830.1 - 1.6e-07 31.3 0.0 2.2e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Peptidase_C13 PF01650.18 EIM82831.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family DUF4698 PF15769.5 EIM82831.1 - 1.3 8.0 9.6 0.072 12.1 4.6 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) PTPLA PF04387.14 EIM82832.1 - 5.1e-50 169.4 3.9 2.2e-49 167.3 3.9 2.0 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA bZIP_1 PF00170.21 EIM82833.1 - 3.3e-06 27.1 14.0 5.6e-06 26.3 8.1 2.8 2 1 1 3 3 3 1 bZIP transcription factor DUF4110 PF13422.6 EIM82833.1 - 0.16 12.1 4.1 0.48 10.5 4.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) TFIIA PF03153.13 EIM82833.1 - 2.8 7.8 12.3 3.9 7.4 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NIF PF03031.18 EIM82834.1 - 2.2e-54 183.4 0.3 2.9e-54 183.1 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Macoilin PF09726.9 EIM82837.1 - 5.6e-05 21.9 11.2 5.6e-05 21.9 11.2 3.9 3 2 1 4 4 4 1 Macoilin family Spectrin PF00435.21 EIM82837.1 - 1.1 9.8 4.3 2.7 8.5 1.3 2.5 1 1 1 2 2 2 0 Spectrin repeat Cluap1 PF10234.9 EIM82837.1 - 1.4 8.3 6.3 1.3 8.4 4.7 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 PhzC-PhzF PF02567.16 EIM82838.1 - 1.4e-45 156.0 0.6 1.8e-45 155.6 0.6 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TPR_2 PF07719.17 EIM82839.1 - 1e-29 100.2 27.1 0.0003 20.7 0.5 14.3 16 0 0 16 16 14 7 Tetratricopeptide repeat TPR_1 PF00515.28 EIM82839.1 - 8.6e-29 98.2 17.9 7e-06 25.6 0.2 12.7 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.6 EIM82839.1 - 1.7e-24 86.1 21.2 3.5e-05 24.2 0.0 10.4 8 3 1 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 EIM82839.1 - 4.7e-20 70.1 8.4 0.0094 16.1 0.2 11.6 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 EIM82839.1 - 6e-20 71.3 26.8 0.00029 21.1 0.2 9.4 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EIM82839.1 - 2.1e-18 66.6 26.2 0.00012 22.7 0.8 10.2 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EIM82839.1 - 9.4e-17 60.3 25.7 0.17 12.8 0.2 13.3 9 5 6 15 15 13 5 Tetratricopeptide repeat TPR_7 PF13176.6 EIM82839.1 - 1.1e-11 43.9 10.3 0.0054 16.7 0.4 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIM82839.1 - 1.7e-09 37.2 6.9 0.081 12.6 0.2 8.5 8 2 2 10 10 10 1 TPR repeat TPR_6 PF13174.6 EIM82839.1 - 1.9e-09 37.5 24.9 0.092 13.4 0.1 9.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIM82839.1 - 1.6e-07 31.2 21.5 4.1 8.0 0.1 12.0 14 0 0 14 14 13 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM82839.1 - 2.6e-06 27.6 20.7 0.00099 19.3 0.4 5.8 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EIM82839.1 - 0.00031 20.5 36.4 1.4 8.9 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_4 PF07721.14 EIM82839.1 - 0.4 11.4 7.6 1.8e+02 3.2 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EIM82840.1 - 5.8e-12 45.6 0.1 1.3e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 EIM82840.1 - 1e-10 41.8 0.0 2.2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 EIM82840.1 - 0.00016 21.8 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3795 PF12675.7 EIM82840.1 - 0.026 14.9 2.5 0.066 13.6 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) ZZ PF00569.17 EIM82840.1 - 1.6 8.6 4.3 3.6 7.5 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type PALP PF00291.25 EIM82841.1 - 1e-59 202.4 0.1 3.1e-29 102.3 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme p450 PF00067.22 EIM82842.1 - 3e-70 237.2 0.0 3.5e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CoA_binding_2 PF13380.6 EIM82844.1 - 3.2e-31 108.2 0.0 3.6e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EIM82844.1 - 0.053 14.2 0.0 0.085 13.5 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Glyco_hydro_18 PF00704.28 EIM82845.1 - 1.3e-61 209.1 0.8 1.4e-61 208.9 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NUDIX PF00293.28 EIM82846.1 - 4.4e-18 65.6 0.2 9.5e-18 64.5 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EIM82846.1 - 4.2e-12 46.6 0.0 1.3e-11 45.1 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EIM82846.1 - 0.0027 17.3 0.2 0.0052 16.4 0.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HMG_box PF00505.19 EIM82847.1 - 0.0051 17.2 0.7 0.0082 16.5 0.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box ATP12 PF07542.11 EIM82847.1 - 0.047 13.8 0.4 0.087 12.9 0.4 1.4 1 0 0 1 1 1 0 ATP12 chaperone protein Mito_carr PF00153.27 EIM82848.1 - 3.6e-62 206.3 3.9 1.9e-21 75.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RIBIOP_C PF04950.12 EIM82849.1 - 8.8e-123 409.4 0.0 1.4e-122 408.8 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EIM82849.1 - 5.5e-20 71.3 0.0 2.6e-19 69.1 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain PGA2 PF07543.12 EIM82850.1 - 0.083 12.9 3.1 0.14 12.1 3.1 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DASH_Spc34 PF08657.10 EIM82851.1 - 6.3e-07 29.5 0.7 0.0013 18.6 0.0 2.2 1 1 1 2 2 2 2 DASH complex subunit Spc34 YitT_membrane PF02588.15 EIM82851.1 - 0.033 13.6 0.3 0.05 12.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF4407 PF14362.6 EIM82851.1 - 0.093 12.1 1.6 0.15 11.4 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HeLo PF14479.6 EIM82851.1 - 0.15 11.9 0.9 0.28 11.0 0.9 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation VirD1 PF07328.11 EIM82851.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 NAD_binding_1 PF00175.21 EIM82852.1 - 1e-08 35.7 0.0 8.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EIM82852.1 - 0.0084 16.2 0.1 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Med27 PF11571.8 EIM82853.1 - 1.7e-11 44.3 0.0 5.2e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 27 DOCK_N PF16172.5 EIM82855.1 - 8.1e-120 400.2 0.0 1.5e-119 399.4 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 EIM82855.1 - 7.5e-81 272.4 0.1 4.3e-80 269.8 0.1 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EIM82855.1 - 3.1e-49 167.4 0.0 5.1e-48 163.5 0.0 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Asp PF00026.23 EIM82856.1 - 1.3e-67 228.4 10.6 1.6e-67 228.1 10.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM82856.1 - 5.8e-13 49.4 2.9 3.2e-08 34.0 0.2 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM82856.1 - 0.004 17.8 4.1 0.027 15.1 1.2 3.3 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EIM82856.1 - 0.025 15.1 0.2 0.15 12.6 0.2 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Helitron_like_N PF14214.6 EIM82857.1 - 5.9e-05 23.4 0.0 8.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SLT_beta PF02258.16 EIM82858.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shiga-like toxin beta subunit DFP PF04127.15 EIM82860.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein SSB PF00436.25 EIM82860.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Single-strand binding protein family PaaB PF06243.11 EIM82860.1 - 0.13 12.5 0.3 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Phenylacetic acid degradation B Queuosine_synth PF02547.15 EIM82861.1 - 0.034 13.3 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein F-box PF00646.33 EIM82862.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain zf-HIT PF04438.16 EIM82866.1 - 8.5e-09 35.1 14.8 1.2e-08 34.7 14.8 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EIM82866.1 - 0.044 13.9 12.1 0.071 13.2 12.1 1.3 1 0 0 1 1 1 0 MYND finger Baculo_E56 PF04639.12 EIM82866.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Fae PF08714.11 EIM82866.1 - 0.22 11.5 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) zf-B_box PF00643.24 EIM82866.1 - 1.1 9.5 7.4 1.6 8.9 7.4 1.2 1 0 0 1 1 1 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.6 EIM82866.1 - 1.6 9.6 8.4 8.6 7.3 7.9 2.0 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Kelch_4 PF13418.6 EIM82867.1 - 4e-22 78.0 2.2 2.9e-11 43.2 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EIM82867.1 - 1.4e-11 44.2 2.8 0.00037 20.7 0.2 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EIM82867.1 - 1.4e-10 41.2 23.7 1.1e-05 25.5 0.1 8.3 8 2 0 8 8 8 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EIM82867.1 - 2.3e-10 39.9 1.1 8.1e-07 28.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EIM82867.1 - 1.7e-09 37.3 2.2 0.007 16.3 0.0 5.2 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EIM82867.1 - 6.5e-09 35.6 12.5 0.00069 19.5 0.1 5.6 6 1 0 6 6 6 2 Kelch motif COesterase PF00135.28 EIM82868.1 - 9.5e-70 235.9 0.0 2e-69 234.9 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family ArAE_2 PF10334.9 EIM82868.1 - 2.1e-09 37.5 0.3 5.3e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EIM82868.1 - 3.7e-08 33.6 4.6 3.7e-08 33.6 4.6 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EIM82868.1 - 8e-05 21.4 0.7 0.015 13.9 0.0 2.8 3 0 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 EIM82868.1 - 0.00091 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal Abhydrolase_3 PF07859.13 EIM82868.1 - 0.0023 17.8 0.1 0.0061 16.4 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold ALMT PF11744.8 EIM82868.1 - 0.022 13.6 6.6 0.021 13.7 2.0 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Peptidase_S9 PF00326.21 EIM82868.1 - 0.023 14.2 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family FUSC-like PF12805.7 EIM82868.1 - 0.026 13.6 3.2 1.1 8.2 0.2 2.7 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS DUF4407 PF14362.6 EIM82868.1 - 0.089 12.1 0.0 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GrpE PF01025.19 EIM82868.1 - 0.22 11.2 0.0 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 GrpE Fungal_trans PF04082.18 EIM82869.1 - 5.4e-11 42.0 0.1 1e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM82869.1 - 1.1e-07 31.9 13.1 2.1e-07 30.9 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2 PF01569.21 EIM82870.1 - 2.7e-30 104.9 1.3 5.5e-30 103.9 1.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 EIM82870.1 - 0.00035 20.5 0.3 0.0087 16.0 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5510) DUF2339 PF10101.9 EIM82870.1 - 0.0017 17.0 1.0 0.0023 16.6 1.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF3267 PF11667.8 EIM82870.1 - 0.23 11.8 4.4 2.6 8.4 0.2 2.4 1 1 1 2 2 2 0 Putative zincin peptidase PAP2_3 PF14378.6 EIM82870.1 - 9.7 5.8 11.5 4.3 7.0 7.2 2.4 2 1 0 2 2 2 0 PAP2 superfamily API5 PF05918.11 EIM82873.1 - 9.8e-36 123.6 0.8 1.4e-35 123.2 0.8 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 EIM82873.1 - 3e-05 24.3 1.4 7.3e-05 23.1 0.1 2.3 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 EIM82873.1 - 0.00071 19.7 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EIM82873.1 - 0.0021 16.7 0.3 0.0033 16.1 0.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cytochrom_B561 PF03188.16 EIM82874.1 - 8.1e-06 26.0 7.8 1.4e-05 25.3 7.8 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 EIM82874.1 - 0.00011 21.9 0.1 0.0056 16.4 0.0 2.1 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase FAM176 PF14851.6 EIM82874.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 FAM176 family DUF998 PF06197.13 EIM82874.1 - 4.6 6.8 14.2 0.58 9.7 4.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF998) S-methyl_trans PF02574.16 EIM82875.1 - 1.3e-55 189.2 0.0 1.8e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ribosomal_S2 PF00318.20 EIM82876.1 - 2.8e-29 101.9 0.2 3.8e-15 55.7 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EIM82876.1 - 1.1e-09 39.5 10.6 2e-09 38.7 10.6 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Zn_clus PF00172.18 EIM82878.1 - 0.01 15.9 3.7 0.018 15.2 3.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_q6 PF01058.22 EIM82880.1 - 1.8e-22 79.6 0.1 2.7e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F-box-like PF12937.7 EIM82882.1 - 1.2e-05 25.1 0.1 3.1e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like MafB19-deam PF14437.6 EIM82883.1 - 3e-17 62.7 0.0 4.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EIM82883.1 - 3.6e-17 62.1 0.0 7.9e-17 61.0 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 EIM82883.1 - 0.00011 22.3 0.2 0.00027 21.0 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EIM82883.1 - 0.0005 20.2 0.3 0.0031 17.6 0.3 1.9 1 1 0 1 1 1 1 APOBEC2 APOBEC4_like PF18774.1 EIM82883.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.4 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase NAD1 PF18778.1 EIM82883.1 - 0.0016 18.6 0.1 0.005 17.0 0.0 1.7 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 EIM82883.1 - 0.0048 17.0 0.0 0.014 15.6 0.0 1.6 2 0 0 2 2 2 1 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 EIM82883.1 - 0.0069 16.3 0.2 0.01 15.8 0.2 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 EIM82883.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 EIM82883.1 - 0.056 13.5 0.5 0.14 12.2 0.5 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase RhgB_N PF09284.10 EIM82884.1 - 3e-98 328.4 4.5 5.1e-98 327.6 4.5 1.4 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EIM82884.1 - 3.3e-37 127.9 0.2 8.3e-37 126.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EIM82884.1 - 7.6e-19 67.3 5.1 3.3e-18 65.2 3.3 2.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II HMG_box PF00505.19 EIM82886.1 - 6.4e-12 45.7 0.3 6.4e-12 45.7 0.3 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM82886.1 - 3.9e-07 30.6 0.2 9.3e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain bZIP_1 PF00170.21 EIM82887.1 - 1.7e-05 24.8 4.3 3.1e-05 24.0 4.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor SOG2 PF10428.9 EIM82887.1 - 0.014 14.7 0.4 0.014 14.7 0.4 2.1 1 1 1 2 2 2 0 RAM signalling pathway protein bZIP_2 PF07716.15 EIM82887.1 - 0.015 15.4 5.7 0.028 14.5 5.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper His_Phos_1 PF00300.22 EIM82888.1 - 7e-27 94.4 0.4 4.8e-24 85.1 0.3 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ODAPH PF15848.5 EIM82888.1 - 0.07 13.6 2.4 6.5 7.3 1.0 2.4 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein DUF4633 PF15464.6 EIM82888.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) SBF PF01758.16 EIM82889.1 - 1.2e-46 158.9 18.8 1.2e-46 158.9 18.8 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family SLT PF01464.20 EIM82890.1 - 3.4e-13 49.3 0.1 7.1e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain PP1 PF07430.11 EIM82890.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Pyrid_ox_like PF16242.5 EIM82891.1 - 1.2e-29 102.9 0.1 1.7e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EIM82891.1 - 1.9e-09 37.6 0.0 5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EIM82891.1 - 0.012 16.2 0.0 0.041 14.5 0.0 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase IU_nuc_hydro PF01156.19 EIM82892.1 - 5.5e-56 190.4 0.0 7.2e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RNase_H2-Ydr279 PF09468.10 EIM82893.1 - 4.9e-20 72.3 0.2 9.1e-20 71.5 0.2 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EIM82893.1 - 8.4e-12 45.2 0.0 2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain FERM_F2 PF18377.1 EIM82893.1 - 0.035 14.1 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain Pox_H7 PF04787.12 EIM82893.1 - 0.069 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Late protein H7 Sacchrp_dh_C PF16653.5 EIM82894.1 - 4.5e-69 233.5 0.0 6.8e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EIM82894.1 - 3.3e-19 69.4 0.1 5.8e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 EIM82894.1 - 1.6e-12 47.9 0.0 6.3e-10 39.5 0.0 3.4 3 1 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EIM82894.1 - 4e-08 32.8 0.2 0.0057 16.0 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EIM82894.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EIM82894.1 - 0.0031 17.4 0.2 0.0056 16.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EIM82894.1 - 0.056 13.9 0.1 0.18 12.3 0.1 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EIM82894.1 - 0.15 12.5 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC1 PF03109.16 EIM82895.1 - 1.5e-23 83.2 0.0 2.9e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EIM82895.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUa-2TM PF18179.1 EIM82895.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DUF4646 PF15496.6 EIM82897.1 - 1.1e-24 87.5 0.0 2e-24 86.6 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 EIM82897.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.6 EIM82898.1 - 4.9e-24 85.3 0.0 7.5e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF2964 PF11177.8 EIM82899.1 - 0.017 15.3 0.3 0.068 13.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Metallophos PF00149.28 EIM82900.1 - 3.5e-06 27.7 0.0 5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-MYND PF01753.18 EIM82901.1 - 0.15 12.2 8.7 0.29 11.3 8.7 1.5 1 0 0 1 1 1 0 MYND finger Glyoxal_oxid_N PF07250.11 EIM82902.1 - 5.2e-28 97.9 0.3 1.5e-13 50.5 0.0 4.6 4 1 1 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM82902.1 - 2.3e-23 82.3 0.4 4.6e-23 81.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Arrestin_N PF00339.29 EIM82903.1 - 1.7e-10 41.1 0.0 8.1e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EIM82903.1 - 6.2e-06 26.7 0.0 0.17 12.4 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 EIM82903.1 - 5.4e-05 23.0 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Pyridoxal_deC PF00282.19 EIM82904.1 - 8.9e-23 80.6 0.0 1.3e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EIM82904.1 - 1.4e-07 30.8 0.0 3.1e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EIM82904.1 - 0.00045 19.6 0.5 0.00069 19.0 0.5 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EIM82904.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyoxal_oxid_N PF07250.11 EIM82905.1 - 6.3e-27 94.3 0.2 3.6e-19 68.9 0.1 4.6 4 1 0 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM82905.1 - 7.3e-24 83.9 0.1 1.5e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) GFO_IDH_MocA PF01408.22 EIM82906.1 - 2.1e-17 64.1 0.0 3.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIM82906.1 - 0.1 13.3 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EIM82907.1 - 6.7e-16 59.2 0.0 1.1e-15 58.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIM82907.1 - 0.02 15.6 0.0 0.033 14.8 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Polysacc_lyase PF14099.6 EIM82908.1 - 0.00023 21.1 0.6 0.0019 18.1 0.6 2.1 1 1 0 1 1 1 1 Polysaccharide lyase Mnd1 PF03962.15 EIM82909.1 - 3.3e-18 65.7 0.2 9.1e-18 64.3 0.2 1.8 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 EIM82909.1 - 3.3e-08 33.5 0.2 3.3e-08 33.5 0.2 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DUF4094 PF13334.6 EIM82909.1 - 0.017 15.5 0.3 0.032 14.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TrmB PF01978.19 EIM82909.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB GPP34 PF05719.11 EIM82909.1 - 0.032 14.3 0.1 0.048 13.7 0.1 1.4 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Phage_Mu_Gam PF07352.12 EIM82909.1 - 0.055 13.4 2.9 0.068 13.1 2.9 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF5339 PF17274.2 EIM82909.1 - 0.19 12.6 3.7 1.4 9.8 0.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5339) Pkinase PF00069.25 EIM82910.1 - 9.2e-42 143.2 0.0 1.7e-41 142.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM82910.1 - 8.4e-16 58.0 0.0 5.5e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EIM82910.1 - 0.00012 21.8 0.1 0.00018 21.2 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EIM82910.1 - 0.00022 20.7 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM82910.1 - 0.00062 19.8 0.0 0.0009 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM82910.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIM82910.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain PIP49_C PF12260.8 EIM82910.1 - 0.18 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 EIM82910.1 - 0.19 11.3 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tim17 PF02466.19 EIM82912.1 - 3.4e-30 104.7 8.8 4.7e-30 104.2 8.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-4CXXC_R1 PF10497.9 EIM82913.1 - 6.3e-12 45.6 15.1 7.3e-11 42.2 15.1 2.4 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DR2241 PF18069.1 EIM82913.1 - 0.15 11.9 1.7 0.37 10.7 0.5 2.3 2 0 0 2 2 2 0 DR2241 stabilising domain SWIM PF04434.17 EIM82914.1 - 2.7e-07 30.1 0.5 4.5e-07 29.4 0.5 1.3 1 0 0 1 1 1 1 SWIM zinc finger UPF0020 PF01170.18 EIM82915.1 - 3.7e-08 33.3 0.0 1.7e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EIM82915.1 - 0.0067 16.2 0.0 1.3 8.6 0.0 2.6 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 EIM82915.1 - 0.04 13.2 0.0 0.1 11.9 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase MFS_1 PF07690.16 EIM82916.1 - 1.3e-13 50.6 37.5 1.3e-13 50.6 37.5 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 EIM82917.1 - 4.7e-45 153.4 0.0 6.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM82917.1 - 6.5e-30 104.4 0.0 9.4e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM82917.1 - 2e-09 37.6 0.1 5.8e-09 36.1 0.1 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM82917.1 - 2e-07 30.7 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EIM82917.1 - 0.0022 17.5 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-U1 PF06220.12 EIM82918.1 - 9.4e-12 44.5 1.4 1.5e-11 43.8 1.4 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-TRM13_CCCH PF11722.8 EIM82918.1 - 0.72 9.7 4.1 1.6 8.5 4.1 1.6 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein Muskelin_N PF06588.11 EIM82919.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Muskelin N-terminus His_Phos_2 PF00328.22 EIM82919.1 - 0.16 11.3 0.2 11 5.2 0.0 2.4 1 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Pam16 PF03656.13 EIM82920.1 - 1.5e-18 67.0 0.5 1.5e-10 41.1 0.3 2.4 2 1 0 2 2 2 2 Pam16 Nup96 PF12110.8 EIM82920.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 RPA43_OB PF17875.1 EIM82921.1 - 1.1e-30 106.8 0.0 1.1e-30 106.8 0.0 3.2 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EIM82921.1 - 7.4e-09 35.9 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_polI_A34 PF08208.11 EIM82921.1 - 2.3 8.2 34.5 0.43 10.6 13.4 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 PRP38_assoc PF12871.7 EIM82921.1 - 4.4 8.0 22.0 0.65 10.6 8.6 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Dioxygenase_C PF00775.21 EIM82922.1 - 0.0012 18.3 0.1 0.096 12.1 0.0 2.4 2 0 0 2 2 2 2 Dioxygenase Period_C PF12114.8 EIM82922.1 - 1.4 8.4 3.8 2.5 7.6 3.8 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Fe_hyd_lg_C PF02906.14 EIM82923.1 - 1.1e-59 202.1 0.0 2.9e-59 200.7 0.0 1.7 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain His_Phos_2 PF00328.22 EIM82924.1 - 0.044 13.1 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) PI-PLC-X PF00388.19 EIM82925.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain AA_permease_2 PF13520.6 EIM82927.1 - 2.5e-45 155.1 44.3 3.2e-45 154.8 44.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM82927.1 - 4.3e-15 55.3 44.4 2.7e-14 52.6 44.4 2.2 1 1 0 1 1 1 1 Amino acid permease PDR_assoc PF08370.11 EIM82927.1 - 0.31 10.8 6.0 0.44 10.3 1.2 3.1 2 0 0 2 2 2 0 Plant PDR ABC transporter associated NADH_B2 PF14813.6 EIM82929.1 - 0.00055 19.7 0.1 0.00062 19.5 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SNARE_assoc PF09335.11 EIM82929.1 - 0.068 13.7 0.0 0.068 13.7 0.0 1.0 1 0 0 1 1 1 0 SNARE associated Golgi protein Ferrochelatase PF00762.19 EIM82930.1 - 2.6e-98 329.0 0.0 3e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF3844 PF12955.7 EIM82932.1 - 1.2e-30 105.7 3.7 1.8e-30 105.1 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) AIRS_C PF02769.22 EIM82933.1 - 0.0069 16.5 0.4 0.011 15.9 0.3 1.3 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain PBP_sp32 PF07222.12 EIM82933.1 - 0.15 11.4 3.5 0.17 11.3 3.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ATP-synt_B PF00430.18 EIM82933.1 - 0.21 11.7 17.8 0.3 11.2 17.8 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Prefoldin_2 PF01920.20 EIM82934.1 - 5.6e-22 77.7 5.3 6.9e-22 77.4 5.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EIM82934.1 - 0.032 14.1 3.4 0.067 13.1 0.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF4436 PF14494.6 EIM82934.1 - 0.19 11.0 0.2 0.22 10.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Spc24 PF08286.11 EIM82934.1 - 0.8 10.0 7.0 2.5 8.4 0.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 EIM82934.1 - 2.9 7.7 6.2 2.1 8.1 1.6 2.2 1 1 1 2 2 2 0 Septum formation initiator zf-MYND PF01753.18 EIM82935.1 - 3.7e-09 36.5 14.5 7.3e-09 35.6 14.5 1.5 1 0 0 1 1 1 1 MYND finger Tnp_zf-ribbon_2 PF13842.6 EIM82935.1 - 2 9.3 9.2 4.7 8.1 9.2 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Fungal_trans PF04082.18 EIM82936.1 - 1.8e-08 33.8 0.1 4e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM82936.1 - 9.4e-08 32.1 12.0 1.6e-07 31.3 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4218 PF13960.6 EIM82938.1 - 2e-08 33.9 0.0 2.1e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 EIM82939.1 - 0.051 12.8 0.0 0.38 10.0 0.0 2.2 2 0 0 2 2 2 0 Transposase family tnp2 UPF0181 PF03701.14 EIM82939.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) FAF PF11250.8 EIM82944.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Fantastic Four meristem regulator BTB PF00651.31 EIM82944.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain W2 PF02020.18 EIM82945.1 - 1e-19 70.5 0.3 1e-19 70.5 0.3 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Ground-like PF04155.18 EIM82945.1 - 0.023 15.3 0.0 4.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Ground-like domain DUF3606 PF12244.8 EIM82946.1 - 0.062 13.2 0.2 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Cyclin PF08613.11 EIM82947.1 - 0.00024 21.5 0.0 0.001 19.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EIM82947.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain SieB PF14163.6 EIM82948.1 - 1.4 8.4 2.8 2.2 7.7 2.8 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B RRM_1 PF00076.22 EIM82949.1 - 2e-25 88.4 0.0 2.6e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM82949.1 - 0.0022 18.1 0.0 0.0035 17.4 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif ABC_membrane PF00664.23 EIM82950.1 - 2e-36 126.1 6.4 3.2e-36 125.4 6.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIM82950.1 - 2.2e-35 122.2 0.0 3.7e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIM82950.1 - 6.9e-05 22.4 0.2 0.0014 18.1 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIM82950.1 - 0.00083 19.8 0.4 0.0027 18.1 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM82950.1 - 0.004 17.4 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIM82950.1 - 0.0049 16.7 0.1 0.02 14.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM82950.1 - 0.0076 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EIM82950.1 - 0.0093 15.7 0.2 0.023 14.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EIM82950.1 - 0.0093 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EIM82950.1 - 0.044 14.2 0.0 0.81 10.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EIM82950.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EIM82950.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 EIM82950.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MBD_C PF14048.6 EIM82951.1 - 0.056 14.2 0.8 0.086 13.6 0.8 1.4 1 1 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 NmrA PF05368.13 EIM82952.1 - 1.1e-23 84.0 0.0 4.1e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM82952.1 - 3.5e-11 43.3 0.1 2.1e-10 40.8 0.1 2.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM82952.1 - 0.045 13.7 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 KR domain Glyco_hydro_71 PF03659.14 EIM82953.1 - 5.3e-69 232.8 4.3 6.5e-69 232.5 4.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Alpha_GJ PF03229.13 EIM82954.1 - 0.17 12.4 0.2 0.17 12.4 0.2 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J Vps53_N PF04100.12 EIM82955.1 - 7.4e-82 275.3 0.0 1.2e-81 274.7 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 EIM82955.1 - 4.3e-05 23.5 2.3 0.00022 21.2 0.0 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 EIM82955.1 - 0.00076 18.8 5.6 0.0015 17.9 5.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.6 EIM82955.1 - 0.029 14.2 2.5 0.082 12.7 2.5 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 L1R_F9L PF02442.17 EIM82955.1 - 0.16 11.8 0.5 0.41 10.5 0.5 1.7 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses FlxA PF14282.6 EIM82955.1 - 0.29 11.1 6.9 0.97 9.5 6.1 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF1664 PF07889.12 EIM82955.1 - 1.1 9.3 9.5 0.45 10.6 3.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 EIM82955.1 - 2.5 7.7 9.6 5.9 6.4 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4690 PF15756.5 EIM82956.1 - 0.001 19.7 3.8 0.0013 19.3 0.7 2.8 2 1 0 2 2 2 1 Small Novel Rich in Cartilage Amnionless PF14828.6 EIM82956.1 - 0.092 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 EIM82956.1 - 0.23 11.0 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family VMA21 PF09446.10 EIM82956.1 - 0.44 10.7 1.9 1 9.5 1.9 1.6 1 0 0 1 1 1 0 VMA21-like domain LapA_dom PF06305.11 EIM82956.1 - 0.76 9.6 1.6 1.4 8.8 1.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain His_Phos_2 PF00328.22 EIM82957.1 - 1.2e-44 153.3 0.0 1.4e-44 153.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GCS PF03074.16 EIM82958.1 - 3.5e-168 559.7 0.0 4.2e-168 559.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 EIM82958.1 - 0.04 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) His_Phos_2 PF00328.22 EIM82959.1 - 4.1e-36 125.2 0.0 5.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) UTP25 PF06862.12 EIM82960.1 - 3.5e-165 550.3 0.6 4.3e-165 550.1 0.6 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EIM82960.1 - 0.024 14.4 0.0 0.11 12.3 0.0 2.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase Topoisom_bac PF01131.20 EIM82961.1 - 4.2e-105 352.1 0.0 5.2e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EIM82961.1 - 9.8e-21 73.9 0.1 1.2e-19 70.5 0.0 2.6 3 0 0 3 3 3 1 Toprim domain zf-CCHC PF00098.23 EIM82962.1 - 2.5e-19 68.4 26.4 1.2e-06 28.3 3.3 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-GRF PF06839.12 EIM82962.1 - 1.1e-12 47.8 2.8 1.1e-12 47.8 2.8 3.3 4 0 0 4 4 4 1 GRF zinc finger zf-CCHC_3 PF13917.6 EIM82962.1 - 1.2e-10 41.2 9.1 0.0051 16.7 0.5 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 EIM82962.1 - 5e-06 26.2 19.2 0.04 13.7 1.5 3.9 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.6 EIM82962.1 - 0.012 15.3 13.9 0.058 13.1 2.1 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EIM82962.1 - 0.065 13.0 12.5 3.9 7.3 0.8 3.3 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.8 EIM82962.1 - 0.077 13.4 7.7 5.3 7.4 0.2 3.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G MFS_1 PF07690.16 EIM82963.1 - 1.5e-29 103.1 37.8 2.3e-29 102.5 37.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Mannosyl_trans2 PF04188.13 EIM82964.1 - 3.3e-51 175.0 15.5 5e-51 174.4 15.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Pex24p PF06398.11 EIM82965.1 - 1.7e-28 99.7 17.3 2.2e-27 96.0 17.3 2.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-CCHC PF00098.23 EIM82966.1 - 5.7e-10 38.8 7.0 0.00018 21.5 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EIM82966.1 - 0.0067 16.4 0.7 0.46 10.5 0.1 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIM82966.1 - 0.019 14.7 2.7 0.019 14.7 2.7 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-BED PF02892.15 EIM82966.1 - 0.05 13.6 2.7 0.69 10.0 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-CCHC_4 PF14392.6 EIM82966.1 - 0.065 13.0 7.3 0.95 9.2 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 EIM82966.1 - 0.068 13.0 11.6 0.77 9.7 2.0 3.1 3 0 0 3 3 3 0 Zinc knuckle Asparaginase_2 PF01112.18 EIM82968.1 - 2e-72 243.8 0.0 1e-51 175.8 0.0 2.2 2 0 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.21 EIM82968.1 - 0.041 12.7 0.2 0.083 11.6 0.2 1.5 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Epimerase PF01370.21 EIM82969.1 - 8e-19 68.1 0.0 1.5e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM82969.1 - 8e-11 41.9 0.1 2.2e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM82969.1 - 7e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIM82969.1 - 2.7e-07 29.9 0.0 4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM82969.1 - 1.6e-05 24.2 0.0 0.00057 19.1 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EIM82969.1 - 0.00014 21.5 0.3 0.00027 20.6 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EIM82969.1 - 0.025 14.0 0.1 0.093 12.2 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM82969.1 - 0.13 11.3 0.2 0.25 10.4 0.1 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF3446 PF11928.8 EIM82969.1 - 0.86 9.9 5.6 2.6 8.4 5.6 1.8 1 1 0 1 1 1 0 Early growth response N-terminal domain Dynamitin PF04912.14 EIM82970.1 - 3.3e-64 217.6 12.3 3.9e-64 217.4 12.3 1.1 1 0 0 1 1 1 1 Dynamitin Spc7 PF08317.11 EIM82970.1 - 0.0053 15.7 3.6 0.79 8.5 0.3 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Laminin_II PF06009.12 EIM82970.1 - 0.0066 16.5 6.2 0.069 13.2 0.4 3.0 3 0 0 3 3 3 1 Laminin Domain II OmpH PF03938.14 EIM82970.1 - 0.0089 16.4 2.3 2.3 8.6 0.1 2.4 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 EIM82970.1 - 0.019 15.0 0.8 0.019 15.0 0.8 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EIM82970.1 - 0.026 14.6 5.5 0.68 10.0 0.3 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 EIM82970.1 - 0.03 13.3 2.3 1.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TMF_TATA_bd PF12325.8 EIM82970.1 - 0.052 13.8 5.7 3.4 7.9 0.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TBCC_N PF16752.5 EIM82970.1 - 0.056 13.9 7.9 0.67 10.4 0.4 3.4 2 2 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Ada3 PF10198.9 EIM82970.1 - 0.15 12.2 3.5 3.5 7.8 0.2 2.8 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 COG2 PF06148.11 EIM82970.1 - 0.22 11.6 5.9 2.9 8.0 0.2 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MtrB PF05440.12 EIM82970.1 - 0.24 11.9 0.2 0.89 10.0 0.0 2.0 3 0 0 3 3 1 0 Tetrahydromethanopterin S-methyltransferase subunit B MPS2 PF17060.5 EIM82970.1 - 0.28 10.4 3.6 0.66 9.2 3.6 1.6 1 0 0 1 1 1 0 Monopolar spindle protein 2 EzrA PF06160.12 EIM82970.1 - 0.41 8.8 5.4 0.067 11.4 0.2 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Seryl_tRNA_N PF02403.22 EIM82970.1 - 0.56 10.5 6.8 10 6.4 0.4 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_Gp23 PF10669.9 EIM82970.1 - 1.9 8.8 5.6 0.88 9.9 2.0 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4164 PF13747.6 EIM82970.1 - 2 8.7 8.1 1.3 9.4 0.2 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4164) DUF2408 PF10303.9 EIM82970.1 - 3.7 8.1 8.6 2.9e+02 2.0 0.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF2203 PF09969.9 EIM82970.1 - 4.3 8.1 5.6 5.2 7.8 0.1 2.9 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Con-6 PF10346.9 EIM82972.1 - 1e-43 147.1 9.2 6.5e-16 58.1 2.5 3.1 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 EIM82972.1 - 0.01 15.7 0.0 0.4 10.5 0.1 2.5 3 0 0 3 3 3 0 SpoIIIAH-like protein LytR_C PF13399.6 EIM82972.1 - 0.15 13.1 0.4 1.7 9.7 0.0 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator HbrB PF08539.11 EIM82973.1 - 4.5e-55 186.2 0.0 7.4e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Peptidase_M22 PF00814.25 EIM82974.1 - 3.8e-69 233.4 0.0 4.5e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EIM82974.1 - 0.00099 18.9 0.4 0.55 9.8 0.0 3.1 3 0 0 3 3 3 2 Carbamoyltransferase N-terminus DUF3526 PF12040.8 EIM82974.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) DUF572 PF04502.13 EIM82975.1 - 1.4e-82 278.0 3.3 1.7e-82 277.7 3.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 EIM82975.1 - 0.022 14.7 0.8 0.73 9.8 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Mis14 PF08641.12 EIM82976.1 - 1.1e-07 32.2 1.7 1.1e-07 32.2 0.3 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like MUG113 PF13455.6 EIM82976.1 - 0.046 14.4 0.6 0.28 11.9 0.4 2.1 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Muted PF14942.6 EIM82976.1 - 0.63 10.4 4.4 0.54 10.6 1.7 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein BAG PF02179.16 EIM82977.1 - 0.00023 21.5 0.0 0.00058 20.2 0.0 1.6 1 0 0 1 1 1 1 BAG domain GEN1_C PF18380.1 EIM82978.1 - 4.2e-18 66.2 0.2 4.2e-18 66.2 0.2 2.7 3 1 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EIM82978.1 - 1.1e-16 60.9 0.0 1.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EIM82978.1 - 6.7e-06 26.5 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain SNF2_N PF00176.23 EIM82979.1 - 8.6e-37 126.7 0.0 2.5e-36 125.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM82979.1 - 3.9e-13 49.7 0.0 8.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2439 PF10382.9 EIM82979.1 - 0.00016 21.9 0.1 0.068 13.5 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) ResIII PF04851.15 EIM82979.1 - 0.0019 18.2 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Amidohydro_3 PF07969.11 EIM82980.1 - 1.5e-80 272.0 0.1 1.9e-80 271.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EIM82980.1 - 2.4e-10 40.2 0.0 4.9e-09 36.0 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family zf-rbx1 PF12678.7 EIM82981.1 - 1.7e-12 47.4 2.7 3.1e-12 46.6 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EIM82981.1 - 1.2e-09 38.4 7.9 6.7e-09 35.9 7.9 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM82981.1 - 9e-08 31.9 2.0 1.8e-07 30.9 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM82981.1 - 3.4e-07 30.2 1.3 7.6e-07 29.1 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM82981.1 - 3.6e-06 26.7 4.4 3.6e-06 26.7 4.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM82981.1 - 1.2e-05 25.2 0.5 2.3e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EIM82981.1 - 0.00012 21.9 5.6 0.0011 18.7 1.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EIM82981.1 - 0.00014 21.4 1.6 0.00034 20.2 1.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EIM82981.1 - 0.00037 20.4 5.2 0.002 18.1 5.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM82981.1 - 0.0016 18.2 5.7 0.006 16.4 5.8 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EIM82981.1 - 0.0019 17.9 0.6 0.0019 17.9 0.6 2.6 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EIM82981.1 - 0.0032 17.6 1.9 0.007 16.5 1.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SPX PF03105.19 EIM82981.1 - 0.013 15.5 2.0 0.02 14.8 2.0 1.4 1 0 0 1 1 1 0 SPX domain FANCL_C PF11793.8 EIM82981.1 - 0.032 14.4 0.3 0.071 13.3 0.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EIM82981.1 - 0.59 10.5 2.5 1.2 9.6 2.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EIM82981.1 - 1.7 8.5 3.5 1.2 9.0 1.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YqeY PF09424.10 EIM82982.1 - 1.6e-24 86.6 1.5 1.9e-24 86.4 1.5 1.0 1 0 0 1 1 1 1 Yqey-like protein DUF3349 PF11829.8 EIM82982.1 - 0.088 13.6 1.4 0.98 10.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) MA3 PF02847.17 EIM82982.1 - 0.1 12.6 0.2 1.4 8.9 0.1 2.1 1 1 0 2 2 2 0 MA3 domain Q_salvage PF10343.9 EIM82983.1 - 3.2e-12 46.6 0.0 2.3e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family NAD_kinase PF01513.21 EIM82984.1 - 1.9e-71 240.6 0.0 6.5e-71 238.9 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase DUF3435 PF11917.8 EIM82984.1 - 0.14 11.1 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) NOA36 PF06524.12 EIM82984.1 - 0.18 11.1 11.2 0.42 9.9 11.2 1.6 1 0 0 1 1 1 0 NOA36 protein HSP9_HSP12 PF04119.12 EIM82986.1 - 1.6e-24 86.1 6.6 1.6e-24 86.1 6.6 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 Gti1_Pac2 PF09729.9 EIM82987.1 - 1.2e-31 110.2 11.6 3e-25 89.4 0.1 4.1 3 2 1 4 4 4 3 Gti1/Pac2 family Josephin PF02099.17 EIM82988.1 - 8.6e-47 159.3 0.0 2.1e-46 158.0 0.0 1.7 1 0 0 1 1 1 1 Josephin RAP80_UIM PF18282.1 EIM82988.1 - 0.037 13.8 2.5 0.12 12.1 2.5 2.0 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif ATG27 PF09451.10 EIM82989.1 - 1.2e-60 205.6 0.0 1.5e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EIM82989.1 - 0.00026 20.2 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Cauli_VI PF01693.16 EIM82990.1 - 3.6e-09 36.8 0.0 5.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin HSP9_HSP12 PF04119.12 EIM82991.1 - 3.4e-23 81.8 7.7 3.4e-23 81.8 7.7 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 Pre-PUA PF17832.1 EIM82991.1 - 0.16 12.6 0.2 0.19 12.4 0.2 1.1 1 0 0 1 1 1 0 Pre-PUA-like domain DASH_Duo1 PF08651.10 EIM82992.1 - 2.3e-20 72.2 0.1 3.3e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF3611 PF12263.8 EIM82993.1 - 4.7 7.1 12.1 0.08 12.8 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) TGT PF01702.18 EIM82994.1 - 3.3e-128 427.8 0.0 3.8e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase tRNA-synt_1b PF00579.25 EIM82995.1 - 2.5e-77 260.1 0.0 3.1e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EIM82995.1 - 2.7e-05 24.0 0.5 0.0047 16.7 0.1 2.5 1 1 1 2 2 2 2 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 EIM82995.1 - 0.00024 20.8 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain Peptidase_S10 PF00450.22 EIM82996.1 - 3.8e-78 263.8 0.1 4.8e-78 263.4 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase EMP70 PF02990.16 EIM82997.1 - 4e-199 662.6 0.0 5.1e-199 662.2 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Ribosomal_S9 PF00380.19 EIM82998.1 - 2.6e-42 144.2 1.1 4.1e-42 143.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Pterin_4a PF01329.19 EIM82999.1 - 6.3e-05 23.1 0.4 9.6e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase MDD_C PF18376.1 EIM83000.1 - 3.4e-71 238.9 0.0 4.4e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EIM83000.1 - 1.6e-07 31.5 4.2 3.3e-07 30.4 4.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Exo_endo_phos PF03372.23 EIM83001.1 - 4.6e-19 68.9 0.3 2e-17 63.5 0.3 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EIM83001.1 - 6.9e-13 48.6 6.3 7.3e-06 26.2 3.7 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM83001.1 - 1.6e-11 43.8 8.2 6.9e-09 35.3 5.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EIM83001.1 - 0.011 16.2 3.6 7.3 7.6 0.3 4.5 3 1 1 4 4 4 0 Leucine Rich Repeat Relaxase PF03432.14 EIM83001.1 - 0.2 11.2 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Muskelin_N PF06588.11 EIM83002.1 - 8.5e-34 117.2 0.0 1.5e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 EIM83002.1 - 9.5e-24 83.2 4.3 8.3e-10 38.7 0.1 7.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EIM83002.1 - 1.5e-23 82.3 5.6 4.3e-08 33.0 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EIM83002.1 - 2.4e-21 75.5 4.7 2e-07 30.9 0.0 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EIM83002.1 - 4e-18 65.0 1.3 2.8e-06 27.4 0.1 5.6 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EIM83002.1 - 7.6e-12 44.6 7.0 1.2e-07 31.2 0.4 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EIM83002.1 - 1.5e-11 43.8 3.5 2.7e-05 23.9 0.8 4.0 4 0 0 4 4 4 2 Kelch motif DUF3533 PF12051.8 EIM83003.1 - 4.3e-99 332.0 17.3 5.2e-99 331.7 17.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) bZIP_2 PF07716.15 EIM83004.1 - 3.9e-11 42.9 10.9 7.3e-11 42.0 10.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EIM83004.1 - 0.00019 21.5 9.0 0.00019 21.5 9.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor SR-25 PF10500.9 EIM83004.1 - 0.012 15.3 4.7 0.022 14.4 4.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein bZIP_Maf PF03131.17 EIM83004.1 - 0.029 14.9 4.8 0.084 13.4 4.8 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.18 EIM83004.1 - 0.034 14.4 0.8 0.068 13.5 0.8 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 EIM83004.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC-167 PF15188.6 EIM83004.1 - 0.3 11.5 2.1 0.53 10.7 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-CCCH PF00642.24 EIM83005.1 - 5.8e-09 35.6 2.7 1.3e-08 34.6 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EIM83005.1 - 2.2e-07 30.6 4.5 4e-07 29.8 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM83005.1 - 2.6e-07 30.5 7.9 4.5e-07 29.7 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIM83005.1 - 1.3e-06 28.3 6.2 2.6e-06 27.4 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM83005.1 - 5.4e-06 26.1 7.6 1e-05 25.3 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM83005.1 - 6.4e-06 25.9 8.2 1.3e-05 25.0 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 EIM83005.1 - 6.7e-05 22.8 4.3 0.00013 21.9 4.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 EIM83005.1 - 6.8e-05 23.1 6.3 0.00012 22.3 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 EIM83005.1 - 0.00016 21.7 2.6 0.00036 20.6 2.6 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 EIM83005.1 - 0.0023 17.7 2.9 0.0047 16.7 2.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EIM83005.1 - 0.0051 17.0 7.2 0.012 15.8 7.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EIM83005.1 - 0.046 13.6 6.4 0.087 12.7 6.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EIM83005.1 - 0.13 12.1 3.1 0.25 11.2 3.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ribosomal_L34e PF01199.18 EIM83005.1 - 0.23 11.8 4.9 0.13 12.6 1.5 2.2 2 0 0 2 2 2 0 Ribosomal protein L34e zf-C2H2 PF00096.26 EIM83006.1 - 2e-09 37.3 11.7 0.00013 22.2 3.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM83006.1 - 2.8e-08 33.9 8.2 0.0016 19.1 1.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIM83006.1 - 1.2e-05 25.2 4.9 0.0024 17.8 0.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIM83006.1 - 1.8e-05 24.4 3.9 0.053 13.3 0.1 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-met PF12874.7 EIM83006.1 - 6.3e-05 23.2 2.3 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EIM83006.1 - 0.0036 17.6 1.9 0.46 10.8 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EIM83006.1 - 0.01 16.2 2.0 0.01 16.2 2.0 3.8 3 1 0 3 3 3 0 Zinc-finger double domain zf-Dof PF02701.15 EIM83006.1 - 0.019 15.1 4.0 0.08 13.1 0.2 2.5 1 1 1 2 2 2 0 Dof domain, zinc finger zf-met2 PF12907.7 EIM83006.1 - 0.046 13.9 2.5 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding zf-BED PF02892.15 EIM83006.1 - 0.051 13.6 6.6 0.73 9.9 4.1 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 EIM83006.1 - 0.12 12.8 4.0 0.33 11.3 1.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EIM83006.1 - 0.13 12.2 2.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 EIM83006.1 - 0.23 11.3 4.2 3.8 7.4 0.9 2.3 1 1 1 2 2 2 0 GAGA factor FYVE PF01363.21 EIM83006.1 - 0.26 11.4 3.5 0.61 10.3 3.5 1.6 1 1 0 1 1 1 0 FYVE zinc finger Metallophos PF00149.28 EIM83007.1 - 1.6e-35 123.4 0.2 2.1e-35 123.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIM83007.1 - 0.1 13.0 0.9 0.22 12.0 0.9 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EIM83007.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CRAL_TRIO PF00650.20 EIM83008.1 - 5e-11 42.6 0.0 8.2e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain COesterase PF00135.28 EIM83009.1 - 4.5e-54 184.2 0.0 6.1e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM83009.1 - 1.2e-06 28.5 0.4 2.6e-06 27.5 0.4 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_49 PF13896.6 EIM83010.1 - 2.4e-64 217.8 0.7 1.1e-52 179.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan GTP_EFTU PF00009.27 EIM83013.1 - 3.1e-19 69.3 0.0 8.2e-19 67.9 0.0 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EIM83013.1 - 2.3e-10 40.7 2.2 7.6e-10 39.0 0.8 2.7 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EIM83013.1 - 6.5e-05 23.2 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EIM83013.1 - 0.0069 16.5 0.3 0.037 14.1 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM83013.1 - 0.038 13.5 0.0 0.52 9.8 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIM83013.1 - 0.052 13.4 0.3 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU_D4 PF14578.6 EIM83013.1 - 0.1 12.5 0.3 0.53 10.2 0.2 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Gti1_Pac2 PF09729.9 EIM83014.1 - 1.1e-20 74.6 0.2 7.2e-19 68.6 0.1 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family G_path_suppress PF15991.5 EIM83014.1 - 0.58 10.2 2.4 0.87 9.7 2.4 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor GLTP PF08718.11 EIM83015.1 - 1.9e-45 154.8 0.1 2.9e-45 154.2 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) tRNA-synt_1e PF01406.19 EIM83017.1 - 1.7e-128 428.3 0.0 3.1e-128 427.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EIM83017.1 - 1.8e-08 33.5 1.7 6.2e-05 21.9 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EIM83017.1 - 2.4e-05 22.8 0.0 0.0024 16.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DUF1744 PF08490.12 EIM83017.1 - 0.046 12.3 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) tRNA-synt_1c PF00749.21 EIM83017.1 - 0.18 10.7 0.6 0.5 9.2 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Gti1_Pac2 PF09729.9 EIM83018.1 - 2.3e-25 89.8 0.0 6.4e-22 78.5 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 EIM83019.1 - 7.6e-19 68.5 4.2 3.4e-18 66.4 4.2 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family TFIIA PF03153.13 EIM83020.1 - 1.2e-55 190.2 0.3 9.7e-31 108.2 0.2 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF3533 PF12051.8 EIM83021.1 - 5.4e-100 335.0 18.6 6.4e-100 334.7 18.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 EIM83021.1 - 0.47 10.4 0.0 0.47 10.4 0.0 2.7 2 0 0 2 2 2 0 CDR ABC transporter zf-RING_2 PF13639.6 EIM83022.1 - 1.2e-09 38.4 1.5 2.6e-07 30.8 0.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EIM83022.1 - 2.7e-08 34.0 0.8 4.3e-07 30.1 0.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EIM83022.1 - 7.6e-07 28.9 1.5 7.6e-07 28.9 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM83022.1 - 1.7e-05 24.6 0.5 1.7e-05 24.6 0.5 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EIM83022.1 - 1.7e-05 24.6 0.4 0.00022 21.0 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM83022.1 - 2.4e-05 24.0 3.4 0.0025 17.5 0.0 2.9 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_5 PF14634.6 EIM83022.1 - 0.0004 20.3 0.6 0.00099 19.0 0.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIM83022.1 - 0.00041 20.3 8.8 0.012 15.7 4.1 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EIM83022.1 - 0.00043 20.3 0.7 0.0033 17.4 0.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EIM83022.1 - 0.00073 19.3 1.0 0.0023 17.7 0.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EIM83022.1 - 0.0037 16.9 1.0 0.0037 16.9 1.0 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 EIM83022.1 - 0.016 15.1 0.4 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Rtf2 PF04641.12 EIM83022.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.8 EIM83022.1 - 0.095 12.9 4.7 0.66 10.2 2.4 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain DNA_ligase_ZBD PF03119.16 EIM83022.1 - 0.13 12.3 3.7 0.083 12.9 1.4 1.9 2 0 0 2 2 1 0 NAD-dependent DNA ligase C4 zinc finger domain CTU2 PF10288.9 EIM83022.1 - 0.18 12.1 1.2 5.5 7.3 1.2 2.7 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING_4 PF14570.6 EIM83022.1 - 0.79 9.6 2.7 0.33 10.8 0.2 1.7 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EIM83022.1 - 0.9 9.8 2.8 0.52 10.5 0.4 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EIM83022.1 - 1.8 8.7 3.5 1.1 9.4 1.0 1.8 2 0 0 2 2 2 0 RING-variant domain 5_nucleotid_C PF02872.18 EIM83023.1 - 1e-24 87.6 0.0 2.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EIM83023.1 - 4.8e-05 24.0 0.0 8.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rubis-subs-bind PF09273.11 EIM83024.1 - 3.2e-16 60.2 0.3 8.4e-16 58.8 0.3 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EIM83024.1 - 8e-16 58.9 0.0 3.5e-14 53.5 0.0 2.8 2 1 0 2 2 2 1 SET domain ATP-synt_C PF00137.21 EIM83025.1 - 3.7e-24 84.8 34.3 1.1e-15 57.7 10.4 2.4 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 EIM83025.1 - 1.5 9.2 3.0 7.1 7.1 1.3 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Arf PF00025.21 EIM83026.1 - 2.7e-38 131.2 0.0 7.1e-38 129.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EIM83026.1 - 7.4e-11 41.8 0.0 2.9e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EIM83026.1 - 5.4e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EIM83026.1 - 8.5e-08 31.8 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EIM83026.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 EIM83026.1 - 5.2e-06 26.0 0.0 9.8e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EIM83026.1 - 2.5e-05 23.9 0.0 0.0065 16.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIM83026.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM83026.1 - 0.0042 17.0 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EIM83026.1 - 0.0083 16.6 0.5 0.019 15.5 0.5 1.8 1 1 0 1 1 1 1 ABC transporter DLIC PF05783.11 EIM83026.1 - 0.0086 14.9 0.0 0.41 9.4 0.0 2.0 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 EIM83026.1 - 0.0088 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIM83026.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EIM83026.1 - 0.012 15.2 0.0 0.36 10.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EIM83026.1 - 0.016 15.7 0.3 0.035 14.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIM83026.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 EIM83026.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_16 PF13191.6 EIM83026.1 - 0.047 14.1 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EIM83026.1 - 0.047 13.4 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 EIM83026.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EIM83026.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIM83026.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EIM83026.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EIM83026.1 - 0.17 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 EIM83026.1 - 0.19 11.7 0.4 0.66 9.9 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EIM83026.1 - 0.29 11.7 1.3 0.61 10.6 1.3 1.9 1 1 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 EIM83027.1 - 0.014 16.2 3.7 0.2 12.6 2.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 EIM83027.1 - 0.022 14.4 2.8 0.079 12.5 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-Di19 PF05605.12 EIM83027.1 - 0.031 14.6 1.8 0.062 13.6 1.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EIM83027.1 - 0.1 13.0 0.1 0.4 11.2 0.1 1.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 EIM83027.1 - 0.15 12.6 7.1 0.43 11.1 1.8 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EIM83027.1 - 0.17 11.7 10.5 0.52 10.1 5.8 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 EIM83027.1 - 0.25 11.4 1.6 0.4 10.8 0.1 2.0 2 0 0 2 2 2 0 BED zinc finger AAA_lid_2 PF17863.1 EIM83029.1 - 0.18 11.6 2.6 0.18 11.6 0.3 2.2 2 0 0 2 2 2 0 AAA lid domain Rpr2 PF04032.16 EIM83030.1 - 2.8e-20 72.4 0.3 4.3e-20 71.8 0.3 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain RRF PF01765.19 EIM83031.1 - 4.7e-27 94.9 0.8 7.9e-27 94.2 0.8 1.3 1 0 0 1 1 1 1 Ribosome recycling factor RNA_pol_Rpc4 PF05132.14 EIM83031.1 - 0.0028 18.1 0.4 0.0028 18.1 0.4 1.9 2 0 0 2 2 2 1 RNA polymerase III RPC4 WH2 PF02205.20 EIM83031.1 - 0.096 12.5 2.3 3.6 7.6 0.2 2.6 2 0 0 2 2 2 0 WH2 motif Yippee-Mis18 PF03226.14 EIM83032.1 - 9.1e-15 54.8 0.0 1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CCHC PF00098.23 EIM83033.1 - 2.9e-09 36.6 26.7 0.0064 16.5 0.4 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 EIM83033.1 - 0.0066 16.2 23.6 0.077 12.8 0.1 4.7 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 EIM83033.1 - 1.3 9.1 21.1 11 6.1 0.2 4.2 3 1 1 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.6 EIM83033.1 - 3.3 7.5 24.8 3.5 7.5 1.1 4.3 4 0 0 4 4 4 0 Zinc knuckle ABC_tran PF00005.27 EIM83035.1 - 4.5e-42 143.8 1.8 2.2e-20 73.6 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EIM83035.1 - 6.5e-15 55.7 5.7 0.0027 17.6 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIM83035.1 - 3.2e-13 49.6 0.7 0.0001 21.8 0.2 3.4 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIM83035.1 - 4.6e-09 35.9 0.8 0.0008 19.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 EIM83035.1 - 4.4e-06 27.1 0.1 0.15 12.5 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EIM83035.1 - 6.8e-06 26.1 0.4 0.087 12.7 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EIM83035.1 - 1.5e-05 25.3 0.6 0.004 17.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EIM83035.1 - 3.2e-05 24.1 0.0 0.18 12.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EIM83035.1 - 4.8e-05 23.3 0.1 0.23 11.4 0.0 2.7 2 1 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 EIM83035.1 - 5.7e-05 23.2 2.3 0.4 10.8 0.1 3.7 2 1 1 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM83035.1 - 0.00012 22.5 5.5 0.15 12.5 0.1 2.6 2 1 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 EIM83035.1 - 0.00014 21.2 0.2 0.12 11.6 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain AAA_15 PF13175.6 EIM83035.1 - 0.00014 21.7 1.3 0.25 11.0 0.0 3.0 3 1 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 EIM83035.1 - 0.00036 20.9 0.0 0.97 9.8 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.6 EIM83035.1 - 0.00064 20.0 0.2 0.45 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EIM83035.1 - 0.00082 18.9 0.1 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_tran_Xtn PF12848.7 EIM83035.1 - 0.0032 17.5 3.3 0.0032 17.5 3.3 3.0 3 1 0 3 3 2 1 ABC transporter AAA_25 PF13481.6 EIM83035.1 - 0.0051 16.4 0.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EIM83035.1 - 0.0068 16.9 17.5 1.9 8.9 7.0 4.1 3 1 0 3 3 3 2 AAA domain DUF815 PF05673.13 EIM83035.1 - 0.01 15.0 0.2 0.93 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 EIM83035.1 - 0.012 15.2 0.1 4.5 6.9 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 EIM83035.1 - 0.014 15.4 6.4 0.72 9.9 0.0 3.0 3 1 0 3 3 2 0 Dynamin family IstB_IS21 PF01695.17 EIM83035.1 - 0.016 14.9 0.4 4.6 6.9 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 EIM83035.1 - 0.017 15.1 0.3 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MukB PF04310.12 EIM83035.1 - 0.033 14.0 0.6 1 9.1 0.0 2.7 2 1 1 3 3 3 0 MukB N-terminal AAA_24 PF13479.6 EIM83035.1 - 0.062 13.0 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EIM83035.1 - 0.084 12.8 3.0 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 NTPase TsaE PF02367.17 EIM83035.1 - 0.089 12.8 0.6 15 5.6 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EIM83035.1 - 0.091 12.8 0.0 13 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain PIN PF01850.21 EIM83035.1 - 0.1 13.1 4.2 0.22 12.0 2.9 2.1 2 0 0 2 2 2 0 PIN domain AAA_18 PF13238.6 EIM83035.1 - 0.13 12.9 4.2 12 6.4 2.4 3.4 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EIM83035.1 - 0.34 9.8 5.2 0.61 8.9 0.1 3.0 2 1 1 3 3 3 0 AAA-like domain AAA_27 PF13514.6 EIM83035.1 - 1 8.9 0.0 1 8.9 0.0 3.5 3 1 1 4 4 3 0 AAA domain MmgE_PrpD PF03972.14 EIM83036.1 - 2.9e-157 523.7 0.0 3.4e-157 523.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family zf-SNAP50_C PF12251.8 EIM83038.1 - 8.4e-29 100.7 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Phage_TAC_8 PF10666.9 EIM83038.1 - 0.18 12.1 0.1 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 Fez1 PF06818.15 EIM83039.1 - 0.0011 19.5 11.3 0.0011 19.5 11.3 2.9 3 0 0 3 3 3 1 Fez1 PglZ PF08665.12 EIM83039.1 - 0.57 10.3 8.3 1.1 9.3 0.0 3.4 3 1 1 4 4 4 0 PglZ domain DUF1771 PF08590.10 EIM83040.1 - 0.0018 18.6 6.5 0.0034 17.7 6.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Slu7 PF11708.8 EIM83041.1 - 1.8e-110 368.9 13.2 1.8e-110 368.9 13.2 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EIM83041.1 - 0.077 12.7 0.4 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle SNF2_N PF00176.23 EIM83042.1 - 1.3e-60 205.0 0.7 2.1e-60 204.3 0.7 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 EIM83042.1 - 1.1e-23 83.5 0.2 3.6e-23 81.8 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EIM83042.1 - 3.4e-19 69.2 0.0 7.7e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EIM83042.1 - 6.7e-19 67.5 7.8 1.8e-15 56.6 0.1 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EIM83042.1 - 2.2e-09 37.5 0.0 7.7e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EIM83042.1 - 3.9e-08 33.6 0.8 3.9e-08 33.6 0.8 3.8 3 1 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 HDA2-3 PF11496.8 EIM83042.1 - 1.4e-07 31.0 0.3 4.6e-07 29.3 0.3 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CDH1_2_SANT_HL1 PF18375.1 EIM83042.1 - 5.5e-06 27.0 1.8 1.7e-05 25.4 0.1 2.7 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 ERCC3_RAD25_C PF16203.5 EIM83042.1 - 0.0029 16.9 0.1 0.0057 15.9 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CHDCT2 PF08074.11 EIM83042.1 - 0.076 13.2 0.5 0.54 10.4 0.0 2.7 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain Tfb4 PF03850.14 EIM83043.1 - 5e-87 291.9 0.0 5.9e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Olduvai PF06758.13 EIM83043.1 - 0.0069 16.6 0.1 0.049 13.9 0.0 2.2 2 0 0 2 2 2 1 Olduvai domain Asparaginase_2 PF01112.18 EIM83044.1 - 3.4e-43 147.8 0.1 5.9e-24 84.6 0.1 4.0 4 0 0 4 4 4 4 Asparaginase IF-2B PF01008.17 EIM83046.1 - 4.9e-61 206.4 0.0 5.8e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_S16 PF00886.19 EIM83046.1 - 0.12 12.5 0.0 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S16 Pectate_lyase_3 PF12708.7 EIM83048.1 - 9.5e-100 332.8 21.1 1e-86 290.2 6.9 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EIM83048.1 - 1.5e-08 34.2 1.3 0.004 16.8 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase TPR_16 PF13432.6 EIM83049.1 - 4.3e-12 46.5 5.3 7e-06 26.6 1.1 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM83049.1 - 6.4e-11 42.6 5.7 1.1e-06 29.1 0.6 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM83049.1 - 8.5e-06 26.2 12.0 0.076 13.9 0.1 5.3 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83049.1 - 1.4e-05 24.8 1.8 0.018 15.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83049.1 - 0.0004 20.4 1.9 0.051 13.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM83049.1 - 0.0016 18.7 3.0 0.36 11.1 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EIM83049.1 - 0.002 17.9 1.7 0.17 11.8 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIM83049.1 - 0.0029 17.9 0.3 4.6 7.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM83049.1 - 0.0036 17.1 0.1 0.19 11.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM83049.1 - 0.0044 17.2 0.0 2.7 8.3 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIM83049.1 - 0.019 15.0 0.7 3.3 8.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIM83049.1 - 0.019 15.6 10.6 0.44 11.3 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EIM83049.1 - 0.11 12.2 4.0 0.099 12.3 0.8 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain ATP_transf PF09830.9 EIM83050.1 - 5e-17 61.8 0.0 7.6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase COPI_assoc PF08507.10 EIM83051.1 - 0.084 12.9 3.8 0.21 11.6 3.5 1.8 1 1 0 1 1 1 0 COPI associated protein CE2_N PF17996.1 EIM83052.1 - 0.00067 19.6 0.1 0.93 9.5 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Podoplanin PF05808.11 EIM83052.1 - 0.0087 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 EIM83052.1 - 0.024 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 EIM83052.1 - 0.038 14.9 0.0 0.07 14.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 EIM83052.1 - 0.059 12.2 0.2 0.091 11.6 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Herpes_gE PF02480.16 EIM83052.1 - 0.15 10.8 0.0 0.3 9.8 0.0 1.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF3277 PF11681.8 EIM83052.1 - 0.35 10.7 2.9 5.4 6.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) HicA_toxin PF07927.12 EIM83053.1 - 4.3e-09 36.3 0.0 9.7e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, TFIIA PF03153.13 EIM83053.1 - 0.68 9.9 30.3 1.1 9.2 7.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Clat_adaptor_s PF01217.20 EIM83054.1 - 3e-17 62.9 0.1 1e-16 61.1 0.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Mso1_Sec1_bdg PF14475.6 EIM83054.1 - 0.0014 18.2 0.5 0.094 12.3 0.0 2.6 3 0 0 3 3 3 2 Sec1-binding region of Mso1 Med16 PF11635.8 EIM83056.1 - 1.1e-07 30.2 0.0 1.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 16 ABC_membrane PF00664.23 EIM83057.1 - 1.5e-35 123.2 6.1 2e-35 122.8 6.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIM83057.1 - 4.8e-34 117.8 0.0 9e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIM83057.1 - 1e-05 25.1 0.2 0.00043 19.8 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EIM83057.1 - 0.0018 18.6 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIM83057.1 - 0.0043 17.4 0.4 0.048 14.0 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EIM83057.1 - 0.0066 16.4 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EIM83057.1 - 0.014 15.1 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIM83057.1 - 0.024 14.7 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EIM83057.1 - 0.056 13.2 0.0 0.51 10.1 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SUR7 PF06687.12 EIM83060.1 - 2.1e-19 70.0 6.2 3.4e-19 69.3 6.2 1.3 1 1 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EIM83060.1 - 0.0053 16.6 0.5 0.0088 15.9 0.5 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein Clc-like PF07062.12 EIM83060.1 - 0.0097 15.4 1.4 0.1 12.0 0.8 2.0 2 0 0 2 2 2 1 Clc-like Acyl_transf_3 PF01757.22 EIM83060.1 - 7.5 5.5 16.0 30 3.5 15.9 1.8 1 1 0 1 1 1 0 Acyltransferase family adh_short PF00106.25 EIM83061.1 - 3.2e-20 72.4 0.1 4.9e-19 68.6 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM83061.1 - 9.1e-10 38.5 0.1 3.4e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM83061.1 - 4.9e-08 33.1 0.1 7.8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 KR domain HK PF02110.15 EIM83062.1 - 1.7e-71 240.5 0.8 3.1e-70 236.3 0.8 2.4 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EIM83062.1 - 3e-56 189.6 0.1 6.6e-56 188.5 0.1 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 EIM83062.1 - 0.0038 16.6 0.0 0.038 13.4 0.0 2.3 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase B12-binding PF02310.19 EIM83062.1 - 0.039 14.0 0.1 7.1 6.7 0.0 3.2 3 0 0 3 3 3 0 B12 binding domain Alpha-amylase PF00128.24 EIM83063.1 - 7.5e-53 180.2 0.4 2.3e-52 178.6 0.4 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EIM83063.1 - 1.4e-17 63.8 0.5 2.8e-17 62.8 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 EIM83063.1 - 0.034 13.2 0.1 0.053 12.6 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Hemerythrin PF01814.23 EIM83064.1 - 3.5e-15 56.8 2.1 4.1e-15 56.5 2.1 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Caps_synth PF05704.12 EIM83064.1 - 0.059 12.7 0.0 9.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein DUF1996 PF09362.10 EIM83065.1 - 4.5e-74 249.4 2.5 4.5e-74 249.4 2.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) FAM199X PF15814.5 EIM83065.1 - 0.034 13.2 11.1 0.061 12.4 11.1 1.4 1 0 0 1 1 1 0 Protein family FAM199X Med3 PF11593.8 EIM83065.1 - 0.49 9.5 19.0 1.1 8.4 19.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.7 EIM83066.1 - 0.00092 19.1 0.1 0.005 16.7 0.1 2.3 1 0 0 1 1 1 1 F-box-like DUF3552 PF12072.8 EIM83066.1 - 0.05 13.0 5.9 0.076 12.4 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PhyH PF05721.13 EIM83067.1 - 5.9e-48 163.9 0.0 7.1e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EIM83067.1 - 0.029 14.8 0.0 0.073 13.5 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase TPR_10 PF13374.6 EIM83068.1 - 9.6e-51 168.4 29.1 5.5e-08 32.4 0.1 11.4 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.6 EIM83068.1 - 3.7e-25 88.0 30.8 1.1e-06 28.8 0.9 9.0 7 4 2 9 9 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83068.1 - 2.4e-17 61.5 14.9 0.46 10.7 0.0 10.9 12 0 0 12 12 11 5 Tetratricopeptide repeat ANAPC5 PF12862.7 EIM83068.1 - 1.5e-13 50.6 12.1 1.1 9.4 0.0 9.3 2 2 7 9 9 9 3 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 EIM83068.1 - 2e-11 43.2 5.5 14 6.2 0.0 10.1 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM83068.1 - 1.1e-08 35.2 4.5 1.1 10.0 0.0 8.2 9 1 0 9 9 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 EIM83068.1 - 1.1e-08 35.2 4.9 0.14 12.2 0.0 5.7 2 2 5 7 7 7 4 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 EIM83068.1 - 1.1e-05 25.8 22.6 1.1 10.3 0.0 9.2 6 2 3 9 9 8 1 Tetratricopeptide repeat NACHT PF05729.12 EIM83068.1 - 4.8e-05 23.3 0.1 0.00012 22.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain ImpA_N PF06812.12 EIM83068.1 - 0.00012 22.2 0.1 0.12 12.5 0.0 3.9 4 0 0 4 4 4 1 ImpA, N-terminal, type VI secretion system MIT PF04212.18 EIM83068.1 - 0.00027 20.9 0.5 19 5.4 0.0 4.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EIM83068.1 - 0.00064 19.4 8.9 9.9 6.2 0.0 7.7 11 0 0 11 11 9 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EIM83068.1 - 0.006 16.5 0.6 5.6 6.8 0.0 4.1 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal Bac_luciferase PF00296.20 EIM83068.1 - 0.0062 16.0 0.1 10 5.4 0.0 4.1 3 2 1 4 4 4 0 Luciferase-like monooxygenase TPR_16 PF13432.6 EIM83068.1 - 0.027 15.1 25.8 4.2 8.1 0.7 8.9 6 3 4 10 10 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM83068.1 - 0.05 13.3 6.5 34 4.2 0.0 5.8 7 0 0 7 7 6 0 TPR repeat Peptidase_M19 PF01244.21 EIM83068.1 - 0.06 12.5 0.1 40 3.2 0.0 4.3 3 1 1 4 4 4 0 Membrane dipeptidase (Peptidase family M19) Leptin PF02024.15 EIM83068.1 - 0.1 12.4 0.0 11 5.8 0.0 2.8 1 1 1 2 2 2 0 Leptin TPR_17 PF13431.6 EIM83068.1 - 0.11 12.9 5.3 35 5.1 0.1 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83068.1 - 1.4 9.1 18.2 89 3.5 0.0 8.4 9 1 0 9 9 9 0 Tetratricopeptide repeat C2 PF00168.30 EIM83069.1 - 0.00065 20.0 0.0 0.0009 19.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain 6PGD PF00393.19 EIM83070.1 - 1.1e-85 287.6 0.0 1.3e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EIM83070.1 - 2.2e-29 102.7 0.1 3.3e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EIM83070.1 - 0.0044 16.9 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MR_MLE_N PF02746.16 EIM83070.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Lipase_3 PF01764.25 EIM83071.1 - 5.2e-28 97.7 0.1 7.2e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 EIM83071.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 EIM83071.1 - 0.098 12.2 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Pkinase PF00069.25 EIM83072.1 - 2.2e-68 230.5 0.0 2.9e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83072.1 - 2.4e-36 125.4 0.0 3.2e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EIM83072.1 - 4.4e-15 55.8 0.3 8.4e-15 54.9 0.3 1.5 1 0 0 1 1 1 1 FHA domain APH PF01636.23 EIM83072.1 - 4.1e-06 26.9 0.0 0.0015 18.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 EIM83072.1 - 1.3e-05 25.4 0.1 0.00024 21.3 0.1 2.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EIM83072.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM83072.1 - 0.0043 16.4 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EIM83072.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family LTD PF00932.19 EIM83072.1 - 0.1 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Lamin Tail Domain NmrA PF05368.13 EIM83074.1 - 6.1e-38 130.7 0.0 8e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM83074.1 - 1.2e-16 61.2 0.0 2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM83074.1 - 9.2e-08 32.4 0.0 3.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EIM83074.1 - 0.00052 20.0 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 EIM83074.1 - 0.017 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.6 EIM83074.1 - 0.03 14.8 0.1 0.055 14.0 0.1 1.4 1 0 0 1 1 1 0 CoA binding domain Epimerase PF01370.21 EIM83074.1 - 0.039 13.4 0.0 0.86 9.0 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EIM83074.1 - 0.062 13.4 0.0 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3798 PF12683.7 EIM83074.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Semialdhyde_dh PF01118.24 EIM83074.1 - 0.15 12.5 0.1 0.38 11.2 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Trp_syntA PF00290.20 EIM83074.1 - 0.16 10.8 0.0 2.5 6.9 0.0 2.3 2 1 1 3 3 3 0 Tryptophan synthase alpha chain Amidohydro_3 PF07969.11 EIM83075.1 - 2.8e-15 56.8 0.0 9.5e-07 28.6 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 EIM83075.1 - 2.7e-11 43.4 0.1 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 EIM83075.1 - 0.00097 19.0 3.0 7.6 6.6 0.1 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat zf-MYND PF01753.18 EIM83076.1 - 0.0012 18.8 19.5 0.0023 18.0 15.2 2.5 2 0 0 2 2 2 1 MYND finger CENP-X PF09415.10 EIM83076.1 - 0.013 15.8 0.1 0.034 14.5 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X MFS_1 PF07690.16 EIM83077.1 - 2.1e-17 63.1 42.5 4.2e-17 62.1 40.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF747 PF05346.11 EIM83078.1 - 2.2e-109 365.8 0.6 2.9e-109 365.4 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family RrnaAD PF00398.20 EIM83080.1 - 1.5e-26 93.1 0.0 2.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CASP_C PF08172.12 EIM83081.1 - 1.3e-76 257.2 6.7 1.3e-76 257.2 6.7 3.9 2 1 2 4 4 4 1 CASP C terminal KLRAQ PF10205.9 EIM83081.1 - 0.01 16.0 0.3 0.01 16.0 0.3 6.0 5 2 1 6 6 6 0 Predicted coiled-coil domain-containing protein Shugoshin_N PF07558.11 EIM83081.1 - 0.052 13.4 0.7 0.052 13.4 0.7 5.5 6 1 0 6 6 6 0 Shugoshin N-terminal coiled-coil region CENP-H PF05837.12 EIM83081.1 - 0.36 11.3 0.0 0.36 11.3 0.0 5.9 4 1 2 6 6 6 0 Centromere protein H (CENP-H) BSD PF03909.17 EIM83082.1 - 3.7e-19 68.5 0.4 1.5e-13 50.5 0.1 2.8 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EIM83082.1 - 2.4e-16 59.8 0.2 4.8e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF4097 PF13349.6 EIM83082.1 - 0.05 12.9 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative adhesin WD40 PF00400.32 EIM83084.1 - 6.5e-43 143.9 25.5 2.2e-08 34.6 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM83084.1 - 1.7e-08 34.6 0.9 0.098 13.0 0.0 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIM83084.1 - 0.00056 19.8 1.9 2.9 7.9 0.0 4.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EIM83084.1 - 0.0013 17.5 5.3 0.069 11.8 0.2 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 EIM83084.1 - 0.0049 16.0 0.0 0.47 9.5 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 EIM83084.1 - 0.027 13.0 0.1 1.8 7.0 0.2 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain SCNM1_acidic PF15805.5 EIM83085.1 - 0.14 11.9 0.9 0.38 10.5 0.9 1.7 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Arnt_C PF18583.1 EIM83086.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain LSM PF01423.22 EIM83087.1 - 1.6e-13 50.1 0.2 2.1e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIM83087.1 - 0.0097 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EIM83087.1 - 0.017 15.2 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain E3_binding PF02817.17 EIM83087.1 - 0.02 15.2 0.1 0.053 13.9 0.1 1.7 1 0 0 1 1 1 0 e3 binding domain DUF3510 PF12022.8 EIM83088.1 - 2.4e-32 112.0 0.0 1e-31 109.9 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 EIM83088.1 - 3.1e-26 92.0 4.1 5.6e-26 91.2 1.9 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EIM83088.1 - 0.0068 16.5 0.0 0.029 14.4 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 PB1 PF00564.24 EIM83088.1 - 1.5 8.8 4.2 14 5.7 0.1 3.6 4 0 0 4 4 4 0 PB1 domain Vps8 PF12816.7 EIM83089.1 - 2e-69 233.1 0.0 5.7e-69 231.6 0.0 1.8 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EIM83089.1 - 0.0015 18.4 0.2 0.077 12.9 0.5 2.8 3 1 0 3 3 3 1 Region in Clathrin and VPS PQQ_3 PF13570.6 EIM83089.1 - 0.015 15.7 0.1 2.4 8.8 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 EIM83089.1 - 0.039 14.3 0.0 3 8.2 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Voltage_CLC PF00654.20 EIM83090.1 - 1.6e-93 313.8 20.0 3.4e-93 312.7 17.3 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel DUF2207 PF09972.9 EIM83090.1 - 0.094 11.5 1.5 0.56 8.9 0.4 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.18 EIM83091.1 - 3.1e-22 78.9 0.0 4.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM83091.1 - 9.7e-09 35.2 10.1 1.7e-08 34.5 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EIM83091.1 - 0.17 12.1 0.7 0.77 10.0 0.1 2.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain ADD_DNMT3 PF17980.1 EIM83091.1 - 0.23 11.5 0.7 0.46 10.5 0.7 1.4 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 F-box-like PF12937.7 EIM83092.1 - 0.00011 22.0 0.7 0.00011 22.0 0.7 3.2 5 1 0 5 5 5 1 F-box-like DUF2695 PF10905.8 EIM83092.1 - 0.17 12.1 0.1 3 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) F-box PF00646.33 EIM83092.1 - 0.28 11.1 6.6 0.51 10.3 0.2 3.1 2 1 1 3 3 3 0 F-box domain PseudoU_synth_2 PF00849.22 EIM83093.1 - 7e-33 114.0 0.4 2.2e-32 112.4 0.4 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase GLTSCR1 PF15249.6 EIM83094.1 - 3.5e-27 94.8 0.6 6.9e-27 93.9 0.6 1.5 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Rabaptin PF03528.15 EIM83094.1 - 0.25 10.0 3.6 0.35 9.5 3.6 1.1 1 0 0 1 1 1 0 Rabaptin TPR_1 PF00515.28 EIM83095.1 - 1.6e-31 106.8 11.0 9.9e-06 25.2 0.9 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83095.1 - 4.2e-25 85.8 17.6 0.00052 19.9 0.0 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83095.1 - 2e-23 80.6 9.5 0.001 19.1 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC8 PF04049.13 EIM83095.1 - 3.9e-21 75.6 0.0 2.3e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 EIM83095.1 - 2.4e-17 62.1 14.1 0.00057 20.5 0.0 7.1 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EIM83095.1 - 3.5e-15 55.4 4.2 2.3e-05 24.0 0.7 4.9 3 1 1 4 4 4 4 TPR repeat TPR_12 PF13424.6 EIM83095.1 - 3.8e-13 49.5 13.0 0.0011 19.2 1.4 5.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83095.1 - 1.7e-11 44.5 8.7 5.1e-06 27.0 0.4 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM83095.1 - 3.7e-09 36.9 12.4 0.49 10.9 0.7 5.7 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 EIM83095.1 - 4.3e-08 33.0 10.2 5.9 7.5 0.2 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83095.1 - 9.9e-08 31.5 12.7 0.024 14.6 0.2 5.5 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EIM83095.1 - 4e-06 26.9 5.6 0.079 13.1 1.6 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EIM83095.1 - 2.3e-05 23.7 5.9 0.00079 18.7 1.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM83095.1 - 5.4e-05 23.6 14.8 5 8.0 0.3 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 EIM83095.1 - 0.0036 17.4 3.0 0.038 14.1 0.3 3.1 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EIM83095.1 - 0.012 15.5 5.3 7.2 6.6 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM83095.1 - 0.016 15.4 17.0 0.2 11.9 0.2 5.0 2 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EIM83095.1 - 0.052 12.5 0.1 1.2 8.0 0.0 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PFL-like PF02901.15 EIM83095.1 - 0.1 11.2 3.1 0.13 10.8 3.1 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like Aim21 PF11489.8 EIM83095.1 - 0.12 11.3 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 MIT PF04212.18 EIM83095.1 - 7.5 6.7 10.8 2.9 8.0 0.3 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Alg14 PF08660.11 EIM83096.1 - 1e-53 181.9 0.0 1.3e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF4131 PF13567.6 EIM83096.1 - 0.093 12.4 0.3 0.093 12.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-CCCH PF00642.24 EIM83097.1 - 2.8e-14 52.6 16.0 3.8e-07 29.9 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EIM83097.1 - 0.0026 17.5 0.0 0.0072 16.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 EIM83097.1 - 0.004 17.3 3.1 0.22 11.8 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger containing family Torus PF16131.5 EIM83097.1 - 0.0062 17.2 1.8 1.7 9.4 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 EIM83097.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Zn_clus PF00172.18 EIM83098.1 - 1.5e-07 31.4 5.8 2.7e-07 30.6 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.6 EIM83098.1 - 0.024 14.6 5.2 0.031 14.3 5.2 1.2 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Mito_carr PF00153.27 EIM83099.1 - 1.4e-13 50.5 0.0 2.2e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein ABC_membrane_2 PF06472.15 EIM83099.1 - 0.013 14.9 0.7 0.056 12.8 0.0 2.2 3 0 0 3 3 3 0 ABC transporter transmembrane region 2 DUF1772 PF08592.11 EIM83099.1 - 0.024 15.0 8.2 2.3 8.5 0.2 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Claudin_3 PF06653.11 EIM83099.1 - 0.2 11.6 2.0 11 6.0 0.0 3.1 3 0 0 3 3 3 0 Tight junction protein, Claudin-like Smim3 PF17307.2 EIM83099.1 - 3.7 7.1 7.3 4.4 6.9 0.2 2.6 2 0 0 2 2 2 0 Small integral membrane protein 3 SNF2_N PF00176.23 EIM83101.1 - 8.9e-44 149.6 0.1 5.7e-39 133.8 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM83101.1 - 7.8e-19 68.1 0.0 2.9e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM83101.1 - 3.9e-09 36.8 0.0 8.6e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.7 EIM83101.1 - 8e-06 26.0 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif ERCC3_RAD25_C PF16203.5 EIM83101.1 - 0.0025 17.1 0.2 0.0045 16.2 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Sybindin PF04099.12 EIM83102.1 - 6.6e-20 71.5 0.0 9.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EIM83102.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF1168 PF06658.12 EIM83103.1 - 4.1e-37 127.0 14.6 7.1e-37 126.2 14.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) DUF966 PF06136.13 EIM83103.1 - 0.42 10.3 10.2 0.55 9.9 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CMS1 PF14617.6 EIM83103.1 - 0.51 9.6 4.9 0.75 9.1 4.9 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_S8e PF01201.22 EIM83104.1 - 7.2e-50 168.7 1.1 3e-49 166.7 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein S8e DUF1490 PF07371.12 EIM83104.1 - 0.077 13.1 0.8 0.18 11.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) PH_11 PF15413.6 EIM83104.1 - 0.41 11.1 3.5 1.5 9.3 3.5 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Yip1 PF04893.17 EIM83105.1 - 3.6e-07 30.1 10.3 5e-07 29.6 10.3 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2198 PF09964.9 EIM83106.1 - 1 9.5 3.2 2.6 8.2 3.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) CX9C PF16860.5 EIM83107.1 - 0.0015 18.5 0.6 0.77 9.8 0.1 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 EIM83107.1 - 0.0049 17.1 0.4 0.13 12.5 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EIM83107.1 - 0.018 15.4 0.5 0.024 15.0 0.5 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF1746 PF08508.10 EIM83108.1 - 4.5e-12 46.3 2.4 8.2e-12 45.5 2.4 1.5 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) HeH PF12949.7 EIM83109.1 - 1.4e-07 31.1 0.3 2.4e-07 30.3 0.3 1.4 1 0 0 1 1 1 1 HeH/LEM domain Tho1_MOS11_C PF18592.1 EIM83109.1 - 1.6e-07 31.0 1.2 0.36 10.7 0.3 3.3 3 0 0 3 3 3 3 Tho1/MOS11 C-terminal domain Rho_N PF07498.12 EIM83109.1 - 0.0047 16.8 0.2 0.0047 16.8 0.2 2.3 4 0 0 4 4 4 1 Rho termination factor, N-terminal domain CBFB_NFYA PF02045.15 EIM83110.1 - 1.9e-28 98.8 7.9 2.9e-28 98.2 7.9 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Mso1_Sec1_bdg PF14475.6 EIM83111.1 - 0.13 11.8 1.5 0.91 9.2 0.0 2.5 2 0 0 2 2 2 0 Sec1-binding region of Mso1 Ribosomal_S13 PF00416.22 EIM83112.1 - 8.5e-55 184.6 2.1 9.8e-55 184.4 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EIM83112.1 - 0.0091 14.8 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 EIM83112.1 - 0.031 14.7 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) HHH_6 PF14579.6 EIM83112.1 - 0.035 14.3 0.2 0.13 12.6 0.1 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif tRNA-synt_2c PF01411.19 EIM83113.1 - 8.5e-216 717.7 0.0 1.4e-215 717.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EIM83113.1 - 1e-15 57.5 0.2 2.3e-15 56.4 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EIM83113.1 - 8.3e-12 45.7 5.2 3e-11 43.9 5.2 2.0 1 0 0 1 1 1 1 DHHA1 domain eIF3_N PF09440.10 EIM83113.1 - 0.087 13.3 1.9 0.22 12.0 0.9 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain CLASP_N PF12348.8 EIM83114.1 - 2.6e-19 69.7 0.2 3.2e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 EIM83114.1 - 0.017 15.4 0.1 0.017 15.4 0.1 2.8 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 EIM83114.1 - 0.019 15.5 0.5 0.2 12.2 0.1 2.7 2 2 1 3 3 3 0 HEAT-like repeat IFRD PF05004.13 EIM83114.1 - 0.039 13.1 0.2 0.073 12.2 0.1 1.4 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 EIM83114.1 - 0.044 14.2 0.2 0.14 12.6 0.1 2.0 1 1 0 1 1 1 0 HEAT repeats ENOD40 PF08247.11 EIM83117.1 - 0.77 9.9 0.1 0.77 9.9 0.1 2.4 2 0 0 2 2 2 0 ENOD40 protein KDZ PF18758.1 EIM83118.1 - 9.6e-19 67.9 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM83119.1 - 4.1e-42 142.7 0.3 6.2e-42 142.1 0.3 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM83119.1 - 1.8e-05 24.8 0.2 3.4e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 EIM83119.1 - 0.028 14.6 8.5 0.078 13.2 8.5 1.7 1 0 0 1 1 1 0 B-box zinc finger Hamartin PF04388.12 EIM83121.1 - 7.3 5.1 15.4 10 4.6 15.4 1.2 1 0 0 1 1 1 0 Hamartin protein NOA36 PF06524.12 EIM83123.1 - 0.11 11.7 7.0 0.17 11.1 7.0 1.3 1 0 0 1 1 1 0 NOA36 protein LAT PF15234.6 EIM83123.1 - 0.12 12.1 8.6 0.12 12.1 7.4 1.5 1 1 0 1 1 1 0 Linker for activation of T-cells DUF5563 PF17718.1 EIM83123.1 - 3.3 7.2 10.9 2.4 7.7 6.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5563) CENP-B_dimeris PF09026.10 EIM83123.1 - 6.1 7.3 15.1 17 5.9 15.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2 PF00096.26 EIM83124.1 - 0.0078 16.6 0.5 0.0078 16.6 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF2951 PF11166.8 EIM83124.1 - 0.13 12.5 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Peptidase_C48 PF02902.19 EIM83125.1 - 1.6e-07 31.4 2.0 3.2e-07 30.4 2.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KNOX2 PF03791.13 EIM83125.1 - 0.94 9.0 3.9 0.57 9.7 1.3 2.1 2 0 0 2 2 2 0 KNOX2 domain HTH_7 PF02796.15 EIM83126.1 - 0.023 14.8 0.4 0.047 13.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Plavaka PF18759.1 EIM83127.1 - 1.2e-16 60.9 0.1 1.8e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 EIM83128.1 - 3.2e-61 207.3 3.1 7e-59 199.7 3.1 2.0 1 1 0 1 1 1 1 Plavaka transposase Titin_Z PF09042.11 EIM83128.1 - 0.19 11.7 0.2 0.32 11.0 0.2 1.3 1 0 0 1 1 1 0 Titin Z DDE_Tnp_4 PF13359.6 EIM83130.1 - 0.0015 18.3 0.0 0.0016 18.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EIM83130.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Dimer_Tnp_hAT PF05699.14 EIM83132.1 - 1.7e-08 34.1 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0147 PF03685.13 EIM83132.1 - 0.056 13.5 0.1 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) CAP_GLY PF01302.25 EIM83134.1 - 8.1e-19 67.4 1.9 1.3e-18 66.7 1.9 1.4 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC_3 PF13917.6 EIM83134.1 - 0.052 13.5 1.0 9.7 6.3 1.0 3.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 EIM83134.1 - 0.35 11.0 8.9 0.12 12.5 3.4 2.3 2 0 0 2 2 2 0 Zinc knuckle CLIP1_ZNF PF16641.5 EIM83134.1 - 1.6 8.7 12.5 0.32 10.9 2.3 2.4 2 0 0 2 2 2 0 CLIP1 zinc knuckle DUF2157 PF09925.9 EIM83135.1 - 0.024 14.4 0.2 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) eIF-3c_N PF05470.12 EIM83136.1 - 6.3e-180 599.4 24.2 6.3e-180 599.4 24.2 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EIM83136.1 - 2.3e-12 47.3 0.0 1.6e-11 44.6 0.0 2.5 2 1 0 2 2 2 1 PCI domain SYF2 PF08231.12 EIM83136.1 - 0.015 15.7 4.5 0.015 15.7 4.5 2.9 2 0 0 2 2 2 0 SYF2 splicing factor Hexapep PF00132.24 EIM83137.1 - 1.5e-07 30.8 2.4 0.053 13.3 3.0 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EIM83137.1 - 1.5e-06 28.0 0.0 3.1e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EIM83137.1 - 4e-05 24.0 0.0 6.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EIM83137.1 - 0.0098 14.1 1.0 0.024 12.8 1.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EIM83137.1 - 3.5 7.4 5.9 2.1 8.1 2.4 2.5 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 EIM83138.1 - 1.1e-61 208.5 0.0 1.3e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83138.1 - 1.3e-45 155.7 0.0 1.9e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM83138.1 - 8.4e-05 21.5 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIM83138.1 - 0.00011 21.6 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIM83138.1 - 0.0016 17.5 0.0 0.0078 15.2 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EIM83138.1 - 0.0028 17.6 0.0 0.13 12.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM83138.1 - 0.0047 16.5 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EIM83138.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.20 EIM83139.1 - 1.3e-71 239.6 0.0 1.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EIM83139.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM83139.1 - 0.00069 20.2 0.0 0.00097 19.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EIM83139.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 EIM83139.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 EIM83139.1 - 0.033 14.7 0.0 0.051 14.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EIM83139.1 - 0.11 13.0 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIM83139.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.12 EIM83139.1 - 0.16 11.8 0.0 0.63 9.9 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Ras PF00071.22 EIM83140.1 - 4.8e-50 169.3 0.0 5.6e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM83140.1 - 2.8e-23 82.4 0.0 3.9e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM83140.1 - 7.7e-06 25.5 0.0 1.2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIM83140.1 - 0.027 13.9 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EIM83140.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_C15 PF01470.17 EIM83141.1 - 3.7e-05 24.0 0.1 0.3 11.2 0.1 3.0 2 1 0 2 2 2 2 Pyroglutamyl peptidase MgsA_C PF12002.8 EIM83142.1 - 8.4e-58 195.0 0.2 1.4e-57 194.3 0.2 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.29 EIM83142.1 - 1.1e-16 61.5 0.1 3.7e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 EIM83142.1 - 3.7e-15 56.0 0.1 1.3e-14 54.3 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain RuvB_N PF05496.12 EIM83142.1 - 4.2e-12 46.1 0.0 7.3e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EIM83142.1 - 1e-07 32.0 0.1 5.1e-06 26.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIM83142.1 - 1.8e-07 31.7 1.6 0.00093 19.6 0.1 3.0 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EIM83142.1 - 5.9e-06 26.1 0.0 0.0024 17.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 EIM83142.1 - 7.7e-06 26.2 0.3 0.002 18.4 0.0 2.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EIM83142.1 - 6.7e-05 22.4 0.2 0.071 12.5 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EIM83142.1 - 9e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM83142.1 - 9.4e-05 23.0 0.0 0.00022 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EIM83142.1 - 0.00027 21.2 0.0 0.00055 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EIM83142.1 - 0.00092 19.3 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.14 EIM83142.1 - 0.0021 18.2 0.0 0.0079 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EIM83142.1 - 0.0036 17.5 0.0 0.0081 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EIM83142.1 - 0.0052 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EIM83142.1 - 0.0057 16.6 0.1 1.2 9.0 0.0 2.5 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EIM83142.1 - 0.0065 17.0 0.0 0.018 15.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_3 PF07726.11 EIM83142.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EIM83142.1 - 0.018 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIM83142.1 - 0.02 14.5 0.0 0.051 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIM83142.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 EIM83142.1 - 0.023 13.9 0.0 0.056 12.6 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EIM83142.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 EIM83142.1 - 0.026 14.4 0.1 0.067 13.1 0.0 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain ResIII PF04851.15 EIM83142.1 - 0.038 14.0 0.0 1.5 8.8 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 EIM83142.1 - 0.04 13.7 0.0 0.24 11.2 0.0 1.9 1 1 1 2 2 2 0 DNA polymerase III, delta subunit NACHT PF05729.12 EIM83142.1 - 0.045 13.7 0.2 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain SKI PF01202.22 EIM83142.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_17 PF13207.6 EIM83142.1 - 0.19 12.2 0.0 0.77 10.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 EIM83142.1 - 0.21 10.7 0.0 0.66 9.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TPR_14 PF13428.6 EIM83142.1 - 0.3 12.0 3.7 28 5.9 0.6 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TRP PF06011.12 EIM83143.1 - 2.8e-69 233.9 23.4 3.9e-69 233.4 23.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EIM83143.1 - 3.1e-26 92.4 0.7 4.9e-26 91.7 0.7 1.3 1 0 0 1 1 1 1 ML-like domain MitoNEET_N PF10660.9 EIM83143.1 - 0.35 10.9 2.0 0.47 10.5 0.2 2.2 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Amidohydro_1 PF01979.20 EIM83144.1 - 1.8e-13 50.6 1.2 3.5e-11 43.0 0.1 3.2 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EIM83144.1 - 1.9e-10 40.8 6.8 1.4e-07 31.3 0.1 3.5 3 1 0 3 3 3 2 Amidohydrolase family FAD_binding_5 PF00941.21 EIM83144.1 - 0.077 12.7 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase F-box-like PF12937.7 EIM83145.1 - 5.9e-15 54.9 2.0 1.3e-07 31.4 0.3 3.9 3 0 0 3 3 3 3 F-box-like F-box PF00646.33 EIM83145.1 - 2.7e-05 23.9 8.1 0.0041 16.9 0.4 3.7 3 0 0 3 3 3 2 F-box domain YabA PF06156.13 EIM83146.1 - 0.014 16.1 0.1 0.022 15.4 0.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 EIM83146.1 - 0.29 11.5 3.6 1 9.7 1.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family 2-oxogl_dehyd_N PF16078.5 EIM83147.1 - 0.0019 17.7 0.2 0.0036 16.9 0.2 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus F-box-like PF12937.7 EIM83148.1 - 1.6e-06 27.9 0.8 1.6e-06 27.9 0.8 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM83148.1 - 0.028 14.3 0.3 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 F-box domain DUF2205 PF10224.9 EIM83149.1 - 0.13 12.3 0.4 0.22 11.5 0.4 1.4 1 0 0 1 1 1 0 Short coiled-coil protein XPA_N PF01286.18 EIM83150.1 - 0.011 15.7 0.7 0.021 14.9 0.7 1.4 1 0 0 1 1 1 0 XPA protein N-terminal Cyclin PF08613.11 EIM83152.1 - 5.5e-06 26.8 0.0 8.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EIM83152.1 - 0.0012 18.6 0.1 0.0029 17.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain SERTA PF06031.13 EIM83153.1 - 0.095 12.4 1.6 11 5.8 0.2 2.8 2 0 0 2 2 2 0 SERTA motif Ribonuc_red_sm PF00268.21 EIM83154.1 - 4.8e-105 351.0 0.1 6.1e-105 350.7 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DOR PF14839.6 EIM83157.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 DOR family Glyco_hydro_61 PF03443.14 EIM83161.1 - 1.1e-72 244.3 0.0 1.1e-72 244.3 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 peroxidase PF00141.23 EIM83162.1 - 8.2e-25 87.8 0.0 1.5e-24 86.9 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 EIM83162.1 - 5.4e-23 80.7 2.5 1.2e-22 79.6 2.5 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region ABC_tran PF00005.27 EIM83163.1 - 3.8e-18 66.3 0.0 2.3e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EIM83163.1 - 2.1e-14 53.8 11.7 2.1e-09 37.5 0.2 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.6 EIM83163.1 - 0.00055 19.8 0.4 0.18 11.6 0.1 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIM83163.1 - 0.0096 16.4 0.1 0.029 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EIM83163.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EIM83163.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Shugoshin_N PF07558.11 EIM83164.1 - 0.11 12.4 1.9 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region MCC-bdg_PDZ PF10506.9 EIM83164.1 - 0.9 9.6 5.2 2.3 8.3 2.3 2.6 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Atg14 PF10186.9 EIM83165.1 - 0.0068 15.5 8.1 0.0068 15.5 8.1 4.0 1 1 3 4 4 4 2 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 EIM83165.1 - 0.74 9.9 43.1 0.25 11.4 5.6 5.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 EIM83165.1 - 3 8.5 40.7 0.24 12.1 3.6 5.6 3 2 3 6 6 6 0 Initiation control protein YabA DUF4407 PF14362.6 EIM83165.1 - 4.3 6.6 50.9 3.8 6.8 8.7 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) HALZ PF02183.18 EIM83165.1 - 4.5 7.6 32.1 7.8 6.8 0.4 7.8 8 1 0 8 8 8 0 Homeobox associated leucine zipper DUF948 PF06103.11 EIM83165.1 - 5.9 7.2 12.1 16 5.8 0.3 4.4 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) MCC-bdg_PDZ PF10506.9 EIM83165.1 - 7.9 6.6 23.9 1.8 8.6 0.6 5.5 6 2 1 7 7 7 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TPR_MLP1_2 PF07926.12 EIM83165.1 - 8.9 6.4 56.1 0.34 11.0 10.4 5.3 2 1 4 6 6 6 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 EIM83166.1 - 0.036 14.5 1.2 0.058 13.8 1.2 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HNH_2 PF13391.6 EIM83167.1 - 9.4e-08 32.1 0.2 2.5e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 HNH endonuclease ubiquitin PF00240.23 EIM83168.1 - 1.2e-19 69.8 0.2 1.9e-19 69.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EIM83168.1 - 8.8e-11 41.5 0.1 1.8e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EIM83168.1 - 2.6e-09 36.8 0.6 4.1e-09 36.1 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EIM83168.1 - 1.6e-06 28.6 0.2 2.8e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 EIM83168.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EIM83168.1 - 0.014 15.5 0.1 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EIM83168.1 - 0.04 14.0 1.0 0.67 10.0 1.0 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EIM83168.1 - 0.052 13.9 0.1 0.09 13.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 EIM83168.1 - 0.061 13.3 10.4 0.16 12.0 3.8 2.8 1 1 2 3 3 3 0 STI1 domain GerD PF17898.1 EIM83168.1 - 0.068 13.1 2.6 0.3 11.0 2.6 1.9 1 1 0 1 1 1 0 Spore germination GerD central core domain HOIP-UBA PF16678.5 EIM83168.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair XPC-binding PF09280.11 EIM83168.1 - 3.5 7.4 15.4 0.12 12.1 6.4 2.8 2 1 1 3 3 3 0 XPC-binding domain Glyco_hydro_18 PF00704.28 EIM83169.1 - 1e-54 186.4 0.8 1.3e-54 186.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 EIM83169.1 - 1.8e-12 47.2 0.0 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 PX domain Zot PF05707.12 EIM83172.1 - 0.0033 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA PF00004.29 EIM83172.1 - 0.0063 16.9 0.1 0.011 16.2 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Alpha_GJ PF03229.13 EIM83173.1 - 0.0013 19.3 0.9 0.0027 18.3 0.9 1.5 1 0 0 1 1 1 1 Alphavirus glycoprotein J Gly-zipper_Omp PF13488.6 EIM83173.1 - 0.0096 15.9 1.7 0.02 14.9 1.7 1.5 1 0 0 1 1 1 1 Glycine zipper adh_short PF00106.25 EIM83174.1 - 7e-21 74.6 5.4 8.5e-15 54.7 0.4 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM83174.1 - 9.8e-16 58.0 4.0 9.1e-11 41.8 0.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Fungal_lectin PF07938.12 EIM83175.1 - 0.02 14.3 0.0 0.066 12.6 0.0 1.8 1 1 0 1 1 1 0 Fungal fucose-specific lectin ADH_N PF08240.12 EIM83176.1 - 0.11 12.4 1.5 0.18 11.7 1.5 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_N PF08240.12 EIM83178.1 - 7.1e-26 90.2 5.8 1.2e-25 89.5 5.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM83178.1 - 1.1e-20 73.9 0.1 2.2e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM83178.1 - 0.00012 23.1 0.0 0.0002 22.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EIM83178.1 - 0.059 12.8 0.3 0.098 12.1 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase IGFBP PF00219.18 EIM83178.1 - 0.15 12.7 4.5 0.43 11.3 4.5 1.7 1 0 0 1 1 1 0 Insulin-like growth factor binding protein DUF87 PF01935.17 EIM83179.1 - 0.0028 17.8 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 EIM83179.1 - 0.13 12.5 0.2 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Neuropeptide_S PF14993.6 EIM83179.1 - 0.21 11.4 0.7 9.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Neuropeptide S precursor protein MIP PF00230.20 EIM83180.1 - 4.3e-45 154.2 15.2 5.2e-45 153.9 15.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein zf-MYND PF01753.18 EIM83181.1 - 8.9e-08 32.1 12.0 2.9e-07 30.5 12.1 1.9 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM83181.1 - 0.06 13.7 1.6 0.16 12.3 1.4 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Adeno_E3_CR2 PF02439.15 EIM83182.1 - 0.017 14.8 0.3 0.028 14.2 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 EIM83182.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Protocadherin CE2_N PF17996.1 EIM83182.1 - 0.03 14.3 0.7 11 6.0 0.1 3.1 4 0 0 4 4 4 0 Carbohydrate esterase 2 N-terminal DUF1180 PF06679.12 EIM83182.1 - 0.087 13.2 0.4 0.55 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PRIMA1 PF16101.5 EIM83182.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ATG101 PF07855.12 EIM83183.1 - 1.9e-40 138.4 0.1 2.2e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Prefoldin_2 PF01920.20 EIM83184.1 - 0.15 12.0 0.3 0.15 12.0 0.3 3.9 2 1 2 4 4 4 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 EIM83184.1 - 0.37 10.8 19.2 0.035 14.1 10.0 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EIM83184.1 - 1.4 7.8 20.6 0.057 12.3 9.7 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF641 PF04859.12 EIM83184.1 - 2.1 8.7 14.6 0.43 10.9 2.3 3.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) GAS PF13851.6 EIM83184.1 - 2.7 7.3 17.9 2 7.7 2.9 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 EIM83184.1 - 4.4 7.9 12.6 4.5e+03 -1.7 12.2 3.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal SYCE1 PF15233.6 EIM83184.1 - 7.8 6.5 19.1 0.53 10.3 10.0 2.8 2 1 1 3 3 3 0 Synaptonemal complex central element protein 1 SKN1 PF03935.15 EIM83185.1 - 1.6e-178 594.2 7.8 1.8e-178 594.0 7.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Leu_zip PF15294.6 EIM83187.1 - 0.014 15.0 1.3 0.023 14.3 1.3 1.3 1 0 0 1 1 1 0 Leucine zipper TSC22 PF01166.18 EIM83187.1 - 0.05 13.9 3.4 5.8 7.3 0.6 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family CCDC92 PF14916.6 EIM83187.1 - 0.12 12.2 1.4 1.4 8.7 0.2 2.7 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Jnk-SapK_ap_N PF09744.9 EIM83187.1 - 0.41 10.8 8.1 0.7 10.1 7.6 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Med9 PF07544.13 EIM83187.1 - 0.87 9.7 3.3 1.4 9.1 1.8 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HALZ PF02183.18 EIM83187.1 - 0.91 9.8 5.5 1.7 8.9 1.0 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 EIM83187.1 - 1.3 8.8 8.7 7.1 6.5 2.3 3.2 2 1 1 3 3 3 0 Septum formation initiator NYD-SP28_assoc PF14775.6 EIM83187.1 - 2.4 8.3 9.8 0.86 9.7 4.4 2.7 2 1 1 3 3 3 0 Sperm tail C-terminal domain ZapB PF06005.12 EIM83187.1 - 3.4 8.2 11.5 14 6.2 5.3 2.8 1 1 2 3 3 3 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 EIM83187.1 - 3.4 7.8 9.3 46 4.2 0.0 2.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.15 EIM83187.1 - 4.3 7.5 10.6 0.059 13.5 1.9 2.4 3 0 0 3 3 3 0 Basic region leucine zipper Cnn_1N PF07989.11 EIM83187.1 - 4.6 7.5 6.7 87 3.4 6.0 2.7 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 MARVEL PF01284.23 EIM83188.1 - 2.9e-11 43.6 0.0 0.00026 21.1 0.9 2.2 2 0 0 2 2 2 2 Membrane-associating domain PBP1_TM PF14812.6 EIM83188.1 - 0.0017 18.7 19.1 0.013 15.8 4.4 4.2 4 0 0 4 4 4 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Comm PF15957.5 EIM83188.1 - 0.015 15.6 0.0 1.5 9.2 0.0 3.0 2 1 0 2 2 2 0 Commissureless DUF5408 PF17402.2 EIM83188.1 - 0.02 14.8 0.6 0.02 14.8 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5408) Orf78 PF06024.12 EIM83188.1 - 0.034 14.4 0.0 2.1 8.7 0.0 3.0 3 0 0 3 3 3 0 Orf78 (ac78) FAM176 PF14851.6 EIM83188.1 - 0.47 10.1 0.0 0.47 10.1 0.0 2.9 2 1 1 3 3 3 0 FAM176 family GCIP PF13324.6 EIM83188.1 - 1.5 8.3 4.9 3.8 7.0 2.5 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EIM83188.1 - 2.6 8.5 32.5 7.3 7.0 1.2 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EIM83188.1 - 3.2 7.0 20.6 1.2 8.3 14.3 2.2 2 0 0 2 2 2 0 NOA36 protein Aldo_ket_red PF00248.21 EIM83189.1 - 1.6e-30 106.3 0.1 2.1e-29 102.6 0.1 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family MARVEL PF01284.23 EIM83190.1 - 7.2e-10 39.1 17.6 9e-10 38.7 17.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 EIM83190.1 - 5.3 5.2 7.2 6.8 4.9 7.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPR_12 PF13424.6 EIM83191.1 - 9.7e-45 150.8 8.6 5.1e-18 65.1 0.3 3.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EIM83191.1 - 1.7e-44 148.5 0.8 2.9e-15 55.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83191.1 - 4.2e-14 51.5 0.7 0.00019 21.2 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83191.1 - 3.2e-09 36.3 1.4 0.0029 17.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIM83191.1 - 3.4e-09 36.1 1.4 0.00024 20.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83191.1 - 5.6e-09 35.4 3.1 0.08 13.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM83191.1 - 1.2e-06 28.9 0.3 0.0075 16.8 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIM83191.1 - 3.4e-06 27.0 1.0 0.047 14.1 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM83191.1 - 8.9e-05 22.0 0.4 0.00011 21.7 0.4 1.2 1 0 0 1 1 1 1 MalT-like TPR region PPR PF01535.20 EIM83191.1 - 0.0002 21.4 0.2 11 6.5 0.0 4.2 4 0 0 4 4 4 0 PPR repeat TPR_6 PF13174.6 EIM83191.1 - 0.0002 21.8 0.3 0.029 15.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM83191.1 - 0.00049 20.7 0.2 5.9 8.0 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83191.1 - 0.00057 20.5 0.1 1.9 9.2 0.1 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF2680 PF10925.8 EIM83191.1 - 0.00068 19.6 0.2 1.5 8.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2680) TPR_4 PF07721.14 EIM83191.1 - 0.0026 18.2 0.0 31 5.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM83191.1 - 0.01 16.0 0.4 6.4 7.1 0.0 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5617 PF18493.1 EIM83191.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) DUF848 PF05852.11 EIM83191.1 - 0.18 11.9 2.1 30 4.7 0.0 3.0 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) MARVEL PF01284.23 EIM83193.1 - 7.5e-11 42.2 15.6 1e-10 41.8 15.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ribonuc_L-PSP PF01042.21 EIM83194.1 - 1.9e-40 137.7 0.3 2.4e-40 137.3 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Dor1 PF04124.12 EIM83195.1 - 8.8e-49 166.0 0.0 1.1e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 EIM83195.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Vps51/Vps67 Syntaxin-6_N PF09177.11 EIM83195.1 - 0.14 12.7 0.8 0.84 10.2 0.8 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 EIM83195.1 - 0.21 11.6 0.9 0.94 9.5 1.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dor1 PF04124.12 EIM83196.1 - 7.6e-06 24.8 0.0 0.00039 19.2 0.0 2.0 2 0 0 2 2 2 2 Dor1-like family Exo84_C PF16528.5 EIM83198.1 - 4.3e-39 134.5 0.0 1.3e-38 132.9 0.0 1.9 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EIM83198.1 - 2.5e-15 56.3 0.7 2.5e-15 56.3 0.7 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 EIM83198.1 - 7.4e-07 29.3 4.5 3.3e-06 27.2 2.8 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 PH_13 PF16652.5 EIM83198.1 - 0.0019 18.1 2.0 0.0039 17.0 1.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Sec3-PIP2_bind PF15277.6 EIM83198.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Dus PF01207.17 EIM83199.1 - 2.6e-47 161.4 0.0 5e-47 160.5 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pkinase_fungal PF17667.1 EIM83201.1 - 2.2e-43 148.6 0.0 3.7e-29 101.7 0.0 3.0 1 1 0 2 2 2 2 Fungal protein kinase RNase_H PF00075.24 EIM83201.1 - 6.5e-13 49.1 0.1 2.8e-12 47.0 0.0 2.1 2 1 0 2 2 2 1 RNase H Pkinase_Tyr PF07714.17 EIM83201.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 EIM83201.1 - 0.15 11.4 0.0 0.53 9.6 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain NAD_binding_8 PF13450.6 EIM83202.1 - 2.5e-09 37.2 0.0 7e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EIM83202.1 - 0.00034 19.2 0.0 0.079 11.4 0.0 2.8 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Thi4 PF01946.17 EIM83202.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EIM83202.1 - 0.055 12.7 0.0 0.95 8.6 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sel1 PF08238.12 EIM83203.1 - 2.3e-43 145.6 22.2 1.9e-08 34.7 0.2 7.3 7 0 0 7 7 7 7 Sel1 repeat HNH_repeat PF18780.1 EIM83203.1 - 0.081 12.7 0.2 1 9.2 0.0 2.7 3 0 0 3 3 3 0 Homing endonuclease repeat TPR_6 PF13174.6 EIM83203.1 - 0.2 12.3 6.1 13 6.6 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 EIM83206.1 - 5.8e-35 121.1 0.0 7.3e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_1 PF00561.20 EIM83207.1 - 1.9e-14 53.9 0.0 3.5e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM83207.1 - 1.6e-13 51.8 0.3 2.1e-13 51.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM83207.1 - 2e-10 40.3 0.0 5.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EIM83207.1 - 0.052 13.3 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Acetyltransf_7 PF13508.7 EIM83208.1 - 2.3e-11 43.9 0.0 5.5e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM83208.1 - 2e-09 37.7 0.0 2.8e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM83208.1 - 4.3e-09 36.4 0.0 1.1e-08 35.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM83208.1 - 2.2e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EIM83208.1 - 0.0045 17.1 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM83208.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SNF2_N PF00176.23 EIM83210.1 - 3.7e-68 229.8 0.1 7.8e-68 228.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EIM83210.1 - 1.3e-38 131.6 1.6 1.8e-38 131.0 0.1 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EIM83210.1 - 6.3e-33 113.8 2.2 6.3e-33 113.8 2.2 3.2 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 EIM83210.1 - 1e-19 70.9 0.3 6.9e-19 68.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM83210.1 - 1.5e-09 38.1 0.0 5.7e-09 36.2 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIM83210.1 - 1.5e-05 24.8 0.2 4.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EIM83210.1 - 6.8e-05 22.2 0.0 0.00018 20.8 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 EIM83210.1 - 0.0011 19.3 2.5 0.0011 19.3 2.5 3.8 3 0 0 3 3 3 1 DNA-binding domain AAA_14 PF13173.6 EIM83210.1 - 0.0014 18.6 0.4 0.019 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DEAD_2 PF06733.15 EIM83210.1 - 0.0025 17.5 0.1 0.0061 16.2 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 SWI2_SNF2 PF18766.1 EIM83210.1 - 0.007 16.1 0.1 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EIM83210.1 - 0.03 13.5 0.1 0.03 13.5 0.1 2.7 2 1 1 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase AhpC-TSA_2 PF13911.6 EIM83212.1 - 4.1e-18 65.5 0.0 5.7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EIM83212.1 - 5e-05 23.2 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family EI24 PF07264.11 EIM83213.1 - 0.00014 22.1 7.7 0.00021 21.6 7.7 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AhpC-TSA_2 PF13911.6 EIM83214.1 - 1.2e-19 70.5 0.0 1.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF1802 PF08819.11 EIM83214.1 - 0.00025 20.9 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) AhpC-TSA_2 PF13911.6 EIM83215.1 - 1.7e-21 76.5 0.1 2.2e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EIM83215.1 - 1.1e-07 31.8 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIM83215.1 - 3.1e-07 30.2 0.0 6.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EIM83215.1 - 0.031 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like WD40 PF00400.32 EIM83216.1 - 7.6e-31 105.7 21.3 7.8e-09 36.0 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Goodbye PF17109.5 EIM83216.1 - 5.6e-10 39.7 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain ANAPC4_WD40 PF12894.7 EIM83216.1 - 2.4e-07 31.0 1.7 0.4 11.0 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EIM83216.1 - 4.1e-07 30.1 0.0 2.1e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.12 EIM83216.1 - 1.4e-06 28.0 0.2 3.5 7.7 0.0 5.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EIM83216.1 - 8.9e-05 21.6 1.1 0.29 10.0 0.0 4.1 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EIM83216.1 - 0.00076 19.9 0.0 0.0028 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.6 EIM83216.1 - 0.027 13.8 0.2 0.5 9.6 0.0 2.6 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RNA_helicase PF00910.22 EIM83216.1 - 0.05 14.0 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DUF742 PF05331.11 EIM83216.1 - 0.059 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF742) NB-ARC PF00931.22 EIM83216.1 - 0.065 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF1513 PF07433.11 EIM83216.1 - 0.12 11.4 0.1 6.8 5.7 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) G-alpha PF00503.20 EIM83217.1 - 6.1e-116 387.4 0.0 9.5e-116 386.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM83217.1 - 1.6e-13 50.5 0.2 7.4e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EIM83217.1 - 3.2e-05 24.1 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EIM83217.1 - 0.0044 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Gtr1_RagA PF04670.12 EIM83217.1 - 0.0095 15.3 0.3 2.5 7.4 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EIM83217.1 - 0.0099 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EIM83217.1 - 0.043 13.3 0.0 0.32 10.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EIM83217.1 - 0.074 13.3 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EIM83217.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EIM83217.1 - 0.082 12.5 0.0 12 5.5 0.0 2.6 2 1 0 2 2 2 0 Ras family RNase_H PF00075.24 EIM83218.1 - 2.2e-15 57.1 0.0 3e-14 53.4 0.0 2.1 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EIM83218.1 - 0.0082 16.0 0.9 0.045 13.6 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase-like DASH_Ask1 PF08655.10 EIM83219.1 - 4.8e-18 64.8 0.0 7.5e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 DBD_HTH PF18430.1 EIM83219.1 - 0.26 11.1 1.6 0.63 9.9 1.6 1.7 1 0 0 1 1 1 0 Putative DNA-binding domain VWA PF00092.28 EIM83220.1 - 8.9e-07 29.3 0.1 1.4e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EIM83220.1 - 4e-05 24.2 0.0 7.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EIM83220.1 - 0.0044 17.2 0.1 0.0062 16.7 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Proteasome PF00227.26 EIM83221.1 - 3e-57 193.2 0.0 3.9e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIM83221.1 - 6.3e-14 51.3 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ADH_N PF08240.12 EIM83222.1 - 6.7e-29 100.0 0.4 1.1e-28 99.3 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM83222.1 - 1.2e-16 60.9 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM83222.1 - 1.2e-07 31.4 0.1 2.2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ELFV_dehydrog PF00208.21 EIM83222.1 - 0.07 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GMC_oxred_N PF00732.19 EIM83224.1 - 1.9e-54 185.1 0.0 2.4e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM83224.1 - 2.9e-35 121.9 0.0 4.9e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM83224.1 - 0.00012 21.3 0.4 0.11 11.5 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM83224.1 - 0.00068 19.8 1.1 0.0013 19.0 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM83224.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein CA_like PF10563.9 EIM83224.1 - 0.0023 17.9 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative carbonic anhydrase HI0933_like PF03486.14 EIM83224.1 - 0.015 14.1 0.1 0.021 13.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EIM83224.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM83224.1 - 0.016 14.8 0.2 0.053 13.1 0.3 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EIM83224.1 - 0.022 13.9 0.3 0.041 13.0 0.2 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EIM83224.1 - 0.04 12.8 0.3 0.064 12.1 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 EIM83224.1 - 0.048 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 EIM83224.1 - 0.071 13.7 0.1 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-MYND PF01753.18 EIM83225.1 - 2.6e-08 33.8 11.3 2.6e-08 33.8 11.3 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EIM83225.1 - 0.15 12.3 7.0 0.31 11.4 7.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding UCH PF00443.29 EIM83226.1 - 1.3e-38 133.0 0.0 1.9e-26 93.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EIM83226.1 - 1.7e-17 63.0 0.1 1.1e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 A repeated domain in UCH-protein UCH_1 PF13423.6 EIM83226.1 - 1.2e-08 34.9 0.0 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase NAD_binding_1 PF00175.21 EIM83228.1 - 6.4e-25 87.9 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EIM83228.1 - 2.8e-17 62.9 0.0 4.2e-16 59.1 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EIM83228.1 - 1.6e-07 31.6 0.0 0.00013 22.2 0.0 2.9 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EIM83228.1 - 0.0026 17.9 0.0 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain UbiA PF01040.18 EIM83230.1 - 1.3e-41 142.5 18.5 1.7e-41 142.2 18.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family EndIII_4Fe-2S PF10576.9 EIM83230.1 - 0.25 11.7 1.4 0.51 10.7 1.4 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III STI1 PF17830.1 EIM83232.1 - 0.18 11.8 0.1 0.46 10.5 0.1 1.6 1 0 0 1 1 1 0 STI1 domain efThoc1 PF11957.8 EIM83236.1 - 2.4e-88 297.0 8.7 1.1e-83 281.5 6.1 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor K_channel_TID PF07941.11 EIM83236.1 - 7.9 7.0 20.7 0.53 10.8 3.6 3.1 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Transposase_21 PF02992.14 EIM83237.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 Phage_Gp19 PF09355.10 EIM83238.1 - 0.17 12.3 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 ABC_ATPase PF09818.9 EIM83239.1 - 1.5e-164 548.0 0.0 2.2e-164 547.5 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 EIM83239.1 - 3.2e-05 24.5 0.7 0.00014 22.4 0.1 2.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EIM83239.1 - 0.0006 19.5 0.2 0.0017 18.1 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain HicA_toxin PF07927.12 EIM83240.1 - 2.1e-10 40.4 0.0 4.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, DUF3179 PF11376.8 EIM83241.1 - 0.19 11.1 2.4 0.3 10.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) Arm-DNA-bind_5 PF17293.2 EIM83241.1 - 8.8 6.9 9.4 0.52 10.8 3.5 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Ribosomal_S15 PF00312.22 EIM83243.1 - 6.1e-25 87.2 0.7 1.3e-24 86.1 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 YiiD_C PF09500.10 EIM83244.1 - 4.3 7.2 5.5 11 5.9 0.2 2.3 1 1 1 2 2 2 0 Putative thioesterase (yiiD_Cterm) DDE_3 PF13358.6 EIM83246.1 - 6.2e-08 32.5 0.2 5.5e-05 23.0 0.1 2.9 3 0 0 3 3 3 2 DDE superfamily endonuclease ACT_4 PF13291.6 EIM83247.1 - 0.73 10.5 2.0 17 6.1 0.5 2.7 2 0 0 2 2 2 0 ACT domain LRR_4 PF12799.7 EIM83247.1 - 5.6 7.5 6.1 2.1e+02 2.5 0.4 5.5 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) Kelch_3 PF13415.6 EIM83248.1 - 1 9.7 4.0 6.1 7.3 1.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain F-box-like PF12937.7 EIM83249.1 - 1.3e-06 28.2 0.8 2.7e-06 27.2 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM83249.1 - 0.012 15.5 0.1 0.057 13.3 0.1 2.2 2 0 0 2 2 2 0 F-box domain ChaC PF04752.12 EIM83252.1 - 3.1e-53 180.5 0.0 3.6e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein Beta-lactamase PF00144.24 EIM83254.1 - 6.2e-36 124.3 0.4 2.6e-35 122.2 0.2 2.0 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EIM83254.1 - 0.0041 17.6 0.1 0.0098 16.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Inositol_P PF00459.25 EIM83255.1 - 3.3e-63 213.7 0.0 3.9e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family GDP_Man_Dehyd PF16363.5 EIM83257.1 - 1.3e-45 156.3 0.0 1.6e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EIM83257.1 - 1.4e-42 145.8 0.0 1.8e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM83257.1 - 7.4e-12 44.9 0.0 4.3e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EIM83257.1 - 5.3e-11 42.2 0.0 2.1e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EIM83257.1 - 3.4e-08 33.0 0.1 1.1e-07 31.3 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EIM83257.1 - 1.6e-06 28.1 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EIM83257.1 - 0.001 18.3 0.0 0.0051 16.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EIM83257.1 - 0.026 14.0 0.0 0.19 11.2 0.0 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EIM83257.1 - 0.076 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EIM83257.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.16 EIM83258.1 - 2.7e-35 122.0 25.9 3.6e-35 121.5 25.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Phageshock_PspD PF09584.10 EIM83258.1 - 0.055 13.5 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) DUF1923 PF09083.10 EIM83258.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) Rotamase PF00639.21 EIM83260.1 - 8.9e-24 84.3 0.0 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EIM83260.1 - 2.1e-20 73.4 0.0 3.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EIM83260.1 - 2.4e-08 33.9 0.1 2.4e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EIM83260.1 - 0.0014 19.4 0.0 0.0022 18.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rx_N PF18052.1 EIM83261.1 - 0.0041 17.3 0.5 0.0082 16.4 0.5 1.4 1 0 0 1 1 1 1 Rx N-terminal domain CCDC144C PF14915.6 EIM83261.1 - 0.0058 15.8 4.6 0.0093 15.1 4.6 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region KASH_CCD PF14662.6 EIM83261.1 - 0.0085 15.9 4.4 0.015 15.1 4.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 EIM83261.1 - 0.14 12.7 5.9 0.31 11.5 5.9 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Sec23_trunk PF04811.15 EIM83262.1 - 5.6e-52 176.7 0.0 1e-46 159.5 0.0 2.4 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EIM83262.1 - 1.5e-18 66.5 0.0 3.7e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EIM83262.1 - 8e-15 54.6 5.7 1.5e-14 53.7 5.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EIM83262.1 - 2.9e-14 53.6 0.0 7e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EIM83262.1 - 1.9e-07 30.9 0.2 5.8e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat WW PF00397.26 EIM83262.1 - 0.0013 18.7 0.2 0.0013 18.7 0.2 2.4 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 EIM83262.1 - 0.01 15.2 1.1 0.023 14.1 1.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain NGP1NT PF08153.12 EIM83263.1 - 1.2e-49 167.8 0.9 1.9e-49 167.1 0.0 1.8 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EIM83263.1 - 1.4e-18 67.0 0.1 3.7e-14 52.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM83263.1 - 6.9e-06 25.7 0.4 5.3e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIM83263.1 - 1.6e-05 24.9 0.0 0.00028 20.8 0.0 2.5 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EIM83263.1 - 0.0016 18.0 4.0 0.0058 16.2 0.1 3.0 2 1 0 4 4 4 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EIM83263.1 - 0.0042 16.6 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Serglycin PF04360.12 EIM83263.1 - 0.019 14.9 1.4 0.019 14.9 1.4 1.8 2 0 0 2 2 2 0 Serglycin Roc PF08477.13 EIM83263.1 - 0.057 13.6 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Enolase_C PF00113.22 EIM83264.1 - 3e-146 486.3 0.1 4.1e-146 485.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EIM83264.1 - 4.5e-59 198.3 0.1 7.7e-59 197.6 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EIM83264.1 - 1.3e-07 31.4 0.0 2.6e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EIM83264.1 - 0.0011 18.1 0.2 0.0026 16.9 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Peptidase_S9 PF00326.21 EIM83266.1 - 1.3e-44 152.3 0.3 2e-44 151.6 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EIM83266.1 - 0.017 13.8 0.2 0.48 9.1 0.0 2.1 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EIM83266.1 - 0.029 14.0 4.2 2.8 7.5 2.0 2.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold IBN_N PF03810.19 EIM83267.1 - 2.4e-10 40.2 0.1 2e-09 37.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 EIM83267.1 - 6.5e-07 28.2 0.2 0.00091 17.8 0.1 2.6 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus ParcG PF10274.9 EIM83267.1 - 0.00041 20.5 0.4 2.7 8.1 0.0 3.4 3 0 0 3 3 3 2 Parkin co-regulated protein UTP15_C PF09384.10 EIM83267.1 - 0.012 15.3 0.0 0.057 13.1 0.0 2.2 2 0 0 2 2 2 0 UTP15 C terminal Xpo1 PF08389.12 EIM83267.1 - 0.019 15.0 0.3 0.49 10.4 0.0 3.5 3 1 0 3 3 3 0 Exportin 1-like protein HEAT PF02985.22 EIM83267.1 - 0.028 14.7 3.4 0.52 10.7 0.0 4.9 5 1 1 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 EIM83267.1 - 0.058 13.8 1.1 3.1 8.2 0.0 3.9 3 2 1 5 5 5 0 HEAT repeats Adaptin_N PF01602.20 EIM83267.1 - 0.14 10.7 0.2 1.6 7.2 0.0 2.7 3 0 0 3 3 3 0 Adaptin N terminal region ThiJ_like PF17124.5 EIM83267.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 ThiJ/PfpI family-like HEAT_EZ PF13513.6 EIM83267.1 - 3 8.4 8.8 13 6.4 0.0 5.4 7 0 0 7 7 7 0 HEAT-like repeat HicA_toxin PF07927.12 EIM83268.1 - 1.7e-08 34.4 0.1 6e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, Epimerase PF01370.21 EIM83269.1 - 1.5e-15 57.3 0.0 2.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM83269.1 - 1.9e-12 47.2 0.0 3.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM83269.1 - 4.5e-06 26.0 0.0 0.00072 18.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EIM83269.1 - 6.1e-05 22.2 0.0 0.00057 19.0 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM83269.1 - 0.00037 20.4 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM83269.1 - 0.003 17.1 0.0 0.0061 16.1 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EIM83269.1 - 0.09 12.2 0.2 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Pkinase PF00069.25 EIM83270.1 - 1.2e-66 224.8 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83270.1 - 8.3e-32 110.5 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM83270.1 - 1.1e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIM83270.1 - 0.00076 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM83270.1 - 0.0008 18.8 0.1 0.0021 17.4 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM83270.1 - 0.0016 17.8 0.0 0.046 13.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EIM83270.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EIM83270.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Sugar_tr PF00083.24 EIM83272.1 - 1.2e-116 390.3 11.8 1.5e-116 390.0 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM83272.1 - 9.2e-18 64.3 33.7 4.5e-13 48.8 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VHS PF00790.19 EIM83273.1 - 0.011 15.6 0.1 0.021 14.7 0.1 1.4 1 1 0 1 1 1 0 VHS domain UCH PF00443.29 EIM83274.1 - 1.3e-55 188.7 0.0 1.5e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM83274.1 - 1.5e-31 110.2 0.1 3.5e-30 105.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EIM83274.1 - 0.0018 17.8 2.4 0.16 11.4 2.3 3.1 3 1 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_hydro_47 PF01532.20 EIM83275.1 - 5e-149 497.1 0.0 5.7e-149 496.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GMC_oxred_N PF00732.19 EIM83276.1 - 8.5e-64 215.8 0.0 1.1e-63 215.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM83276.1 - 3.2e-34 118.5 0.0 6.5e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EIM83276.1 - 0.0017 17.7 0.1 0.0036 16.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM83276.1 - 0.0022 17.3 0.2 0.069 12.4 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM83276.1 - 0.0044 17.2 0.4 0.011 15.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM83276.1 - 0.019 14.6 1.3 0.037 13.6 0.3 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EIM83276.1 - 0.021 14.1 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EIM83276.1 - 0.047 12.7 0.2 0.074 12.1 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 EIM83276.1 - 0.18 12.1 0.3 0.47 10.7 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 EIM83276.1 - 0.27 10.3 4.6 2.8 6.9 0.7 2.5 3 0 0 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.6 EIM83276.1 - 0.46 10.5 2.1 0.38 10.7 0.2 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-C2H2 PF00096.26 EIM83277.1 - 7.8e-10 38.7 11.9 2.4e-05 24.5 3.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM83277.1 - 1.8e-09 37.6 10.1 3.3e-08 33.6 1.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM83277.1 - 1.2e-06 28.8 11.6 0.0019 18.8 1.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EIM83277.1 - 0.00088 19.9 6.2 0.031 14.9 0.8 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EIM83277.1 - 0.0011 19.2 0.4 0.0025 18.1 0.4 1.5 1 1 0 1 1 1 1 C2H2-type zinc ribbon Tudor_2 PF18104.1 EIM83277.1 - 0.03 14.0 0.1 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain zf-met PF12874.7 EIM83277.1 - 0.075 13.4 3.1 4.8 7.7 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EIM83277.1 - 0.13 12.5 1.1 0.13 12.5 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TauD PF02668.16 EIM83278.1 - 2.8e-35 122.4 0.1 7.2e-35 121.1 0.1 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 EIM83279.1 - 1.2e-43 149.8 0.0 1.5e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GMC_oxred_N PF00732.19 EIM83280.1 - 5.8e-63 213.0 0.0 3e-62 210.7 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM83280.1 - 4.8e-34 117.9 0.2 1e-33 116.8 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EIM83280.1 - 0.00073 18.9 0.2 0.0015 17.8 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM83280.1 - 0.0019 18.4 0.1 0.005 17.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM83280.1 - 0.015 14.4 1.2 1.5 7.9 1.1 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EIM83280.1 - 0.017 14.7 0.3 0.044 13.4 0.3 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM83280.1 - 0.026 13.8 0.2 0.26 10.5 0.3 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM83280.1 - 0.031 13.5 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EIM83280.1 - 1 8.4 4.9 0.084 11.9 0.3 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein EF-hand_7 PF13499.6 EIM83281.1 - 1.3e-26 92.8 13.6 1e-13 51.5 4.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EIM83281.1 - 3.3e-26 88.8 18.1 2.4e-09 36.1 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EIM83281.1 - 3.7e-22 76.3 12.8 2e-08 33.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EIM83281.1 - 2.3e-14 53.0 15.0 2.4e-09 36.9 1.6 3.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EIM83281.1 - 4.8e-11 42.8 2.5 0.00014 22.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EIM83281.1 - 5e-11 41.6 7.1 0.0011 18.3 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EIM83281.1 - 1e-08 35.1 5.9 0.00049 20.0 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EIM83281.1 - 0.00013 21.9 3.5 0.065 13.2 0.0 3.7 2 1 2 4 4 4 1 Caleosin related protein DUF1636 PF07845.11 EIM83281.1 - 0.011 16.2 0.0 3.5 8.1 0.0 2.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1636) SPARC_Ca_bdg PF10591.9 EIM83281.1 - 0.015 15.6 4.0 0.56 10.5 0.3 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1059 PF06348.11 EIM83281.1 - 0.028 14.7 0.6 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) EF-hand_14 PF17959.1 EIM83281.1 - 0.038 14.3 2.9 0.7 10.3 0.4 2.4 2 1 0 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 EIM83281.1 - 0.06 13.2 0.4 2.9 7.7 0.1 2.3 2 0 0 2 2 2 0 SurA N-terminal domain MgtE_N PF03448.17 EIM83281.1 - 3.1 8.5 7.7 0.71 10.5 1.6 2.4 3 0 0 3 3 2 0 MgtE intracellular N domain zf-C2H2 PF00096.26 EIM83282.1 - 5.5e-12 45.4 6.4 1.8e-05 25.0 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM83282.1 - 1.7e-07 31.5 6.5 0.0016 19.1 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM83282.1 - 9e-06 25.9 11.5 9.4e-06 25.8 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EIM83282.1 - 0.032 14.2 0.5 0.032 14.2 0.5 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EIM83282.1 - 0.13 12.4 3.7 4.1 7.5 0.8 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 EIM83282.1 - 0.15 11.9 12.9 0.16 11.8 1.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 EIM83282.1 - 0.22 11.3 6.6 0.35 10.7 1.7 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Beta-lactamase PF00144.24 EIM83283.1 - 6.9e-42 143.9 0.1 9.6e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DLH PF01738.18 EIM83284.1 - 8.2e-13 48.4 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family MFS_1 PF07690.16 EIM83285.1 - 1.1e-39 136.4 48.2 4.7e-39 134.3 43.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3021 PF11457.8 EIM83285.1 - 0.017 15.5 3.8 0.017 15.5 3.8 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF3021) Methyltransf_3 PF01596.17 EIM83286.1 - 5.6e-42 143.3 0.0 7.1e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EIM83286.1 - 4.4e-15 56.6 0.0 7.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIM83286.1 - 7.3e-05 22.6 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EIM83286.1 - 0.00019 22.1 0.0 0.00035 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM83286.1 - 0.00051 19.9 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM83286.1 - 0.00072 20.2 0.0 0.0017 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EIM83286.1 - 0.021 14.9 0.0 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase FkbM domain CMAS PF02353.20 EIM83286.1 - 0.062 12.6 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EIM83286.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit CPSase_L_D2 PF02786.17 EIM83287.1 - 2.9e-66 223.0 0.0 4.8e-66 222.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EIM83287.1 - 4.3e-46 156.0 1.1 2.6e-45 153.5 0.1 2.5 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EIM83287.1 - 8e-31 106.3 0.0 1.4e-23 83.0 0.0 2.6 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EIM83287.1 - 5e-11 42.3 6.6 5e-11 42.3 6.6 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EIM83287.1 - 1.2e-06 28.2 0.0 4.1e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Ntox43 PF15537.6 EIM83287.1 - 0.011 15.8 0.0 0.039 14.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin 43 Biotin_lipoyl_2 PF13533.6 EIM83287.1 - 0.023 14.5 3.0 0.14 12.0 0.3 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 EIM83287.1 - 0.088 13.5 1.9 15 6.4 0.1 2.7 1 1 1 2 2 2 0 HlyD family secretion protein CRS1_YhbY PF01985.21 EIM83287.1 - 0.21 11.8 3.3 27 5.0 3.3 3.2 2 1 0 2 2 2 0 CRS1 / YhbY (CRM) domain DUF2118 PF09891.9 EIM83287.1 - 3.7 7.5 10.0 6.1 6.8 3.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) MFS_1 PF07690.16 EIM83288.1 - 7.5e-42 143.5 46.2 9.7e-42 143.1 41.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HSCB_C PF07743.13 EIM83289.1 - 3e-15 56.5 10.0 3e-15 56.5 10.0 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EIM83289.1 - 1.9e-08 34.3 0.5 5.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Pex24p PF06398.11 EIM83290.1 - 2.6e-12 46.4 0.5 3.8e-12 45.9 0.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Zot PF05707.12 EIM83293.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 EIM83293.1 - 0.0074 16.6 0.1 1.8 8.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain DEAD PF00270.29 EIM83293.1 - 0.047 13.4 0.0 0.18 11.6 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase EspB PF05802.11 EIM83294.1 - 0.024 14.6 0.4 0.024 14.6 0.4 2.6 2 0 0 2 2 2 0 Enterobacterial EspB protein Eisosome1 PF12757.7 EIM83294.1 - 0.03 14.6 2.9 0.092 13.0 2.9 1.9 1 0 0 1 1 1 0 Eisosome protein 1 DUF948 PF06103.11 EIM83294.1 - 0.11 12.7 0.3 0.55 10.5 0.1 2.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) SesA PF17107.5 EIM83294.1 - 0.16 12.2 1.1 0.48 10.6 0.3 1.9 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Flagellin_N PF00669.20 EIM83294.1 - 0.22 11.6 2.4 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Baculo_PEP_C PF04513.12 EIM83294.1 - 0.24 11.5 3.6 0.17 11.9 0.3 2.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ubiquitin PF00240.23 EIM83295.1 - 6.4e-204 660.2 32.1 2.5e-33 113.6 0.5 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 EIM83295.1 - 3e-93 305.7 35.0 5.7e-15 54.9 0.6 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIM83295.1 - 3.1e-33 114.1 16.7 0.00084 19.8 0.1 8.1 6 6 0 6 6 6 6 Ubiquitin-like domain TBK1_ULD PF18396.1 EIM83295.1 - 8.8e-23 80.0 8.3 0.06 13.3 0.0 6.2 6 0 0 6 6 6 6 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EIM83295.1 - 1.3e-20 73.5 6.5 0.21 11.7 0.0 7.1 6 5 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EIM83295.1 - 4e-20 72.0 16.0 0.083 13.3 0.1 6.1 6 0 0 6 6 6 6 Ubiquitin-like domain DUF2407 PF10302.9 EIM83295.1 - 1.6e-18 67.2 4.5 0.66 10.6 0.0 6.2 1 1 1 6 6 6 6 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 EIM83295.1 - 5.6e-11 42.2 3.6 1.8 7.8 0.0 5.2 5 0 0 5 5 5 5 RNA methyltransferase Big_7 PF17957.1 EIM83295.1 - 6.8e-09 36.4 1.0 52 4.7 0.0 6.1 6 0 0 6 6 6 0 Bacterial Ig domain DUF2870 PF11069.8 EIM83295.1 - 7.8e-09 35.8 0.0 50 4.4 0.0 6.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2870) TmoB PF06234.12 EIM83295.1 - 2.5e-08 33.9 0.1 50 4.1 0.0 6.7 6 0 0 6 6 6 0 Toluene-4-monooxygenase system protein B (TmoB) Ubiquitin_4 PF18036.1 EIM83295.1 - 4.8e-08 32.9 40.9 27 4.9 0.2 11.9 12 0 0 12 12 12 0 Ubiquitin-like domain DUF3861 PF12977.7 EIM83295.1 - 9.9e-08 32.1 8.4 23 5.3 0.0 6.2 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EIM83295.1 - 1.9e-07 30.8 9.3 19 5.2 0.0 6.3 6 0 0 6 6 6 0 ACT domain UDP-g_GGTase PF06427.11 EIM83295.1 - 4e-07 30.1 8.8 12 6.0 0.0 5.8 6 0 0 6 6 6 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EIM83295.1 - 2.2e-06 27.3 0.3 38 3.6 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 EIM83295.1 - 1.8e-05 25.3 4.0 1.2e+02 3.4 0.0 6.2 6 0 0 6 6 6 0 ACT domain DUF493 PF04359.14 EIM83295.1 - 5.6e-05 23.6 0.2 2.3e+02 2.4 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EIM83295.1 - 8.4e-05 22.6 0.0 1.5e+02 2.6 0.0 6.0 6 0 0 6 6 6 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EIM83295.1 - 0.0074 16.4 11.8 1.1e+02 3.1 0.1 6.0 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 EIM83295.1 - 0.081 12.8 17.8 72 3.4 0.1 6.3 6 0 0 6 6 6 0 FlgD Ig-like domain Tash_PEST PF07708.11 EIM83295.1 - 0.33 11.2 44.7 9.8 6.5 1.4 6.3 6 0 0 6 6 6 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 EIM83295.1 - 1.1 9.8 16.7 2.4e+02 2.3 0.1 5.8 1 1 1 2 2 1 0 Phage tail sheath protein beta-sandwich domain PI3K_p85B PF02192.16 EIM83295.1 - 9.5 6.0 16.8 1.6e+02 2.2 0.1 6.0 6 0 0 6 6 6 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 EIM83295.1 - 9.6 6.4 18.9 1.6e+02 2.5 0.1 6.2 6 0 0 6 6 6 0 Cnl2/NKP2 family protein WD40 PF00400.32 EIM83296.1 - 3.9e-59 195.2 9.0 1.5e-09 38.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM83296.1 - 7.4e-28 96.7 0.9 2.4e-05 24.5 0.0 6.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM83296.1 - 3e-14 53.3 0.0 3.7e-06 27.0 0.0 3.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EIM83296.1 - 1.6e-09 37.0 3.9 0.2 10.2 0.2 5.1 1 1 4 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM83296.1 - 9.9e-09 34.9 0.0 6e-05 22.5 0.0 3.7 2 1 2 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 EIM83296.1 - 6.5e-08 31.9 1.8 0.12 11.3 0.7 3.9 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EIM83296.1 - 0.00015 21.0 0.1 0.0084 15.2 0.1 2.4 2 1 1 3 3 3 1 Coatomer WD associated region Kelch_6 PF13964.6 EIM83296.1 - 0.00087 19.5 0.3 0.0098 16.2 0.0 2.9 4 0 0 4 4 4 1 Kelch motif Utp8 PF10395.9 EIM83296.1 - 0.00095 17.8 0.0 0.0012 17.4 0.0 1.1 1 0 0 1 1 1 1 Utp8 family Nucleoporin_N PF08801.11 EIM83296.1 - 0.001 17.9 2.1 1.8 7.2 0.1 4.5 1 1 2 4 4 4 1 Nup133 N terminal like DUF1513 PF07433.11 EIM83296.1 - 0.0027 16.8 0.1 0.47 9.5 0.0 3.2 2 1 2 4 4 4 1 Protein of unknown function (DUF1513) Peptidase_S9_N PF02897.15 EIM83296.1 - 0.01 14.7 0.0 0.87 8.3 0.1 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain IKI3 PF04762.12 EIM83296.1 - 0.018 13.1 0.3 0.21 9.5 0.1 2.4 2 1 0 2 2 2 0 IKI3 family Frtz PF11768.8 EIM83296.1 - 0.069 11.5 0.0 0.59 8.4 0.0 2.3 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 EIM83296.1 - 0.079 12.7 0.5 11 5.7 0.1 3.0 3 1 1 4 4 4 0 TUP1-like enhancer of split PALB2_WD40 PF16756.5 EIM83296.1 - 0.088 11.7 1.2 5.8 5.7 0.0 3.3 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain YqhR PF11085.8 EIM83297.1 - 8 6.4 10.8 0.44 10.4 3.3 2.3 2 1 0 2 2 2 0 Conserved membrane protein YqhR adh_short PF00106.25 EIM83298.1 - 7.9e-49 165.8 0.9 1e-48 165.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM83298.1 - 2.3e-41 141.9 0.2 3e-41 141.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM83298.1 - 4.3e-14 52.8 0.0 6.1e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM83298.1 - 0.00065 18.9 0.2 0.00083 18.6 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EIM83298.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RICH PF05062.12 EIM83298.1 - 0.15 12.5 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 RICH domain 2OG-FeII_Oxy PF03171.20 EIM83300.1 - 0.00017 22.0 0.0 0.00073 20.0 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIM83300.1 - 0.00032 21.4 0.0 0.00067 20.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Nucleolin_bd PF16725.5 EIM83300.1 - 0.032 13.9 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Nucleolin binding domain Ribosomal_S14 PF00253.21 EIM83301.1 - 5.2e-14 51.7 3.6 5.6e-14 51.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Glyco_transf_28 PF03033.20 EIM83302.1 - 1.5e-28 99.5 0.0 3.3e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EIM83302.1 - 2.3e-20 72.6 0.2 4.7e-11 42.6 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 EIM83302.1 - 4.7e-12 46.4 0.1 1.1e-11 45.2 0.1 1.7 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 EIM83302.1 - 1.5e-05 24.0 0.0 3.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 EIM83302.1 - 0.00017 22.0 2.0 0.022 15.2 2.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EIM83302.1 - 0.0076 16.5 0.3 0.043 14.1 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 EIM83302.1 - 0.076 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain SUR7 PF06687.12 EIM83303.1 - 8.9e-19 68.0 6.5 1.1e-18 67.6 6.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 EIM83303.1 - 0.0034 17.2 0.9 0.0034 17.2 0.9 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF5336 PF17270.2 EIM83303.1 - 0.051 13.2 3.5 0.34 10.5 1.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5336) DUF2207 PF09972.9 EIM83303.1 - 0.3 9.8 3.8 0.53 9.0 3.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CAP_N PF01213.19 EIM83305.1 - 0.97 8.8 2.7 1.2 8.6 2.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 EIM83306.1 - 0.0059 17.4 12.4 0.38 11.7 0.0 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat Frtz PF11768.8 EIM83306.1 - 0.025 12.9 0.0 0.038 12.3 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 EIM83306.1 - 0.032 14.5 0.3 5.7 7.3 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TMEM135_C_rich PF15982.5 EIM83307.1 - 4.9e-08 33.6 0.0 1.1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Lactamase_B_2 PF12706.7 EIM83308.1 - 3.1e-25 88.9 0.0 2.5e-24 85.9 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM83308.1 - 0.00057 19.9 0.7 0.0011 19.1 0.7 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CAP PF00188.26 EIM83311.1 - 1.4e-22 80.8 1.4 2.1e-22 80.3 1.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CSN8_PSD8_EIF3K PF10075.9 EIM83312.1 - 1.1e-22 80.5 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PUF PF00806.19 EIM83313.1 - 3.3e-58 190.2 8.9 1.1e-07 31.1 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF1168 PF06658.12 EIM83313.1 - 0.0015 18.3 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) IFT43 PF15305.6 EIM83313.1 - 0.038 14.2 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Atg14 PF10186.9 EIM83314.1 - 1.5e-09 37.4 0.0 8.2e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 NleF_casp_inhib PF16809.5 EIM83314.1 - 0.0083 16.0 0.9 0.015 15.2 0.9 1.3 1 0 0 1 1 1 1 NleF caspase inhibitor VPS38 PF17649.1 EIM83314.1 - 0.011 14.6 0.0 1.4 7.7 0.0 3.4 3 1 0 3 3 3 0 Vacuolar protein sorting 38 Vpu PF00558.19 EIM83315.1 - 0.033 13.9 0.3 0.056 13.2 0.3 1.4 1 0 0 1 1 1 0 Vpu protein RIC1 PF07064.13 EIM83316.1 - 9.9e-100 333.1 0.5 1.4e-99 332.6 0.5 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EIM83316.1 - 0.015 15.6 0.1 1.2 9.5 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIM83316.1 - 0.046 13.7 0.7 12 6.0 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PRELI PF04707.14 EIM83317.1 - 3.6e-34 117.9 0.0 4.3e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Phage_T4_Ndd PF06591.11 EIM83317.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) SRP68 PF16969.5 EIM83318.1 - 4e-83 280.3 11.7 1.4e-81 275.2 6.7 2.1 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 ArsA_ATPase PF02374.15 EIM83319.1 - 3.1e-113 378.0 1.0 3.6e-113 377.8 1.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EIM83319.1 - 7.6e-14 52.0 0.0 2.6e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EIM83319.1 - 9.7e-13 48.3 0.0 2.5e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EIM83319.1 - 6.3e-06 25.8 0.0 3.4e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EIM83319.1 - 1.4e-05 24.7 3.4 8e-05 22.2 0.8 3.0 1 1 2 3 3 3 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EIM83319.1 - 2.2e-05 24.1 0.0 5.8e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EIM83319.1 - 6e-05 22.8 0.4 0.0013 18.4 0.1 2.4 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.16 EIM83319.1 - 0.0058 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 EIM83319.1 - 0.0063 16.1 0.4 0.044 13.4 0.4 2.1 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 EIM83319.1 - 0.054 12.8 0.5 0.13 11.6 0.1 1.9 2 1 0 2 2 2 0 VirC1 protein ATP_bind_1 PF03029.17 EIM83319.1 - 0.058 13.2 1.0 0.74 9.5 1.0 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EIM83319.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIM83319.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EIM83319.1 - 0.23 11.9 1.3 4 7.9 0.1 3.1 2 2 0 3 3 3 0 RNA helicase bZIP_1 PF00170.21 EIM83320.1 - 3.5e-10 39.8 15.1 6.6e-10 38.9 15.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EIM83320.1 - 1.4e-08 34.9 0.0 1.4e-08 34.9 0.0 4.1 3 2 0 3 3 1 1 Transcription factor PAP1 bZIP_2 PF07716.15 EIM83320.1 - 0.0036 17.4 17.4 0.0061 16.6 15.7 2.0 1 1 1 2 2 2 1 Basic region leucine zipper CCDC85 PF10226.9 EIM83320.1 - 0.0037 17.0 1.5 0.0082 15.8 1.5 1.5 1 0 0 1 1 1 1 CCDC85 family SHE3 PF17078.5 EIM83320.1 - 0.0054 16.5 6.1 0.0091 15.7 6.1 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DED PF01335.21 EIM83320.1 - 0.014 15.6 1.6 0.03 14.6 1.6 1.4 1 0 0 1 1 1 0 Death effector domain TSC22 PF01166.18 EIM83320.1 - 0.026 14.8 3.8 0.08 13.3 2.3 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 EIM83320.1 - 0.048 13.4 3.5 0.094 12.5 3.5 1.4 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 EIM83320.1 - 0.048 14.3 1.1 0.1 13.2 1.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA APC_u15 PF16636.5 EIM83320.1 - 0.055 13.9 0.2 0.055 13.9 0.2 3.2 3 1 1 4 4 3 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF5094 PF17015.5 EIM83320.1 - 0.74 9.9 7.5 1.3 9.1 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) bZIP_Maf PF03131.17 EIM83320.1 - 2 9.0 12.1 1.5 9.4 10.3 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor GvpL_GvpF PF06386.11 EIM83320.1 - 2.1 8.2 5.0 3.4 7.5 5.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.19 EIM83320.1 - 2.2 6.1 4.1 2.9 5.7 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Erf4 PF10256.9 EIM83321.1 - 5.6e-32 110.3 0.1 7.6e-32 109.8 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_1 PF00515.28 EIM83322.1 - 1e-46 154.9 24.0 2.5e-07 30.2 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83322.1 - 5.6e-43 141.6 20.1 7.7e-05 22.5 0.0 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83322.1 - 9.3e-36 119.1 10.1 8.4e-06 25.6 0.0 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83322.1 - 8.5e-28 96.7 3.2 3e-06 27.8 0.0 6.9 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 EIM83322.1 - 9.8e-24 83.7 9.8 0.00019 21.9 0.2 7.0 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EIM83322.1 - 1e-22 79.5 23.0 3.4e-06 26.6 0.4 9.1 6 2 3 9 9 9 5 TPR repeat TPR_17 PF13431.6 EIM83322.1 - 1.8e-22 78.0 11.6 0.002 18.4 0.3 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 EIM83322.1 - 1.5e-21 75.5 11.9 0.006 17.1 0.0 9.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 EIM83322.1 - 8.5e-20 69.8 11.6 0.0019 18.9 0.0 9.4 3 2 6 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 EIM83322.1 - 1.1e-19 70.4 17.7 0.00026 21.2 0.0 7.9 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83322.1 - 4.7e-19 67.0 13.1 0.051 13.6 0.0 9.5 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EIM83322.1 - 5.3e-12 45.7 10.1 0.0072 16.5 0.1 5.5 4 1 2 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM83322.1 - 4e-10 39.8 6.6 8.3e-06 25.9 0.7 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EIM83322.1 - 3.4e-06 26.5 5.0 0.032 13.4 2.3 4.7 1 1 3 4 4 4 3 Tetratricopeptide repeat DUF2225 PF09986.9 EIM83322.1 - 0.0041 16.9 0.9 0.76 9.5 0.0 2.9 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 EIM83322.1 - 0.0058 16.9 2.3 0.02 15.2 0.1 3.0 4 1 0 5 5 2 1 Tetratricopeptide repeat SNAP PF14938.6 EIM83322.1 - 0.0074 15.7 9.5 2.2 7.7 2.7 4.3 2 2 2 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 EIM83322.1 - 0.0084 15.5 1.1 1.3 8.3 0.0 3.0 1 1 2 3 3 3 1 MalT-like TPR region ChAPs PF09295.10 EIM83322.1 - 0.01 14.9 0.3 3.3 6.6 0.1 2.4 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 EIM83322.1 - 0.041 13.6 11.8 2 8.1 0.1 4.5 4 2 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF4919 PF16266.5 EIM83322.1 - 0.065 13.2 0.5 4.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 EIM83322.1 - 1.3 8.9 13.2 9 6.3 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat 4F5 PF04419.14 EIM83323.1 - 2.3e-09 38.0 11.8 2.3e-09 38.0 11.8 2.2 2 0 0 2 2 2 1 4F5 protein family Brr6_like_C_C PF10104.9 EIM83324.1 - 4.5e-44 149.4 0.7 7.2e-44 148.8 0.6 1.4 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Ctr PF04145.15 EIM83324.1 - 0.055 14.1 0.0 0.4 11.3 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family PBP1_TM PF14812.6 EIM83324.1 - 0.93 9.9 11.3 0.22 11.9 7.5 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CLP_protease PF00574.23 EIM83325.1 - 8.8e-76 253.8 0.0 1.1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease ECH_1 PF00378.20 EIM83325.1 - 0.068 12.5 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Reprolysin_5 PF13688.6 EIM83326.1 - 1.5e-43 149.3 7.9 1.5e-43 149.3 7.9 2.9 2 1 2 4 4 4 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EIM83326.1 - 2.8e-42 144.8 4.8 7.6e-42 143.4 4.8 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EIM83326.1 - 1.8e-39 135.5 4.0 4.3e-39 134.3 4.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EIM83326.1 - 9.3e-16 58.4 23.8 9.3e-16 58.4 23.8 4.4 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EIM83326.1 - 5.2e-12 46.4 0.0 5.2e-12 46.4 0.0 2.6 3 1 1 4 4 4 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EIM83326.1 - 2.2e-07 31.0 7.1 1.3e-06 28.5 7.1 2.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 EIM83326.1 - 3.3e-06 27.4 0.0 6.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 EIM83326.1 - 0.0001 22.7 9.3 0.0001 22.7 9.3 3.9 2 1 1 3 3 3 1 ADAM cysteine-rich domain Adeno_E3_CR2 PF02439.15 EIM83326.1 - 0.4 10.5 2.5 0.81 9.5 2.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CE2_N PF17996.1 EIM83327.1 - 0.00088 19.2 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal TMEM154 PF15102.6 EIM83327.1 - 0.0056 16.6 2.1 0.027 14.4 0.1 2.7 2 1 0 2 2 2 1 TMEM154 protein family Chorismate_synt PF01264.21 EIM83329.1 - 2.5e-136 453.7 0.1 3e-136 453.5 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase Cdd1 PF11731.8 EIM83329.1 - 0.19 11.9 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus LRR_4 PF12799.7 EIM83332.1 - 0.13 12.8 3.6 0.9 10.0 0.1 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EIM83333.1 - 1.2e-09 37.9 0.7 3.5e-09 36.4 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM83333.1 - 0.3 11.0 8.9 0.16 11.9 1.0 3.1 4 0 0 4 4 4 0 F-box domain DARPP-32 PF05395.12 EIM83333.1 - 0.31 11.3 5.7 0.51 10.5 5.7 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Paf1 PF03985.13 EIM83333.1 - 4.6 6.1 11.4 7 5.5 11.4 1.2 1 0 0 1 1 1 0 Paf1 p450 PF00067.22 EIM83334.1 - 1.6e-48 165.6 0.0 2.1e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UTP15_C PF09384.10 EIM83334.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 UTP15 C terminal Flavin_Reduct PF01613.18 EIM83335.1 - 7.7e-14 52.0 0.0 9.4e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EIM83335.1 - 2.9e-06 27.2 0.1 5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 EIM83335.1 - 0.0042 17.2 0.0 0.0077 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TPR_10 PF13374.6 EIM83336.1 - 5e-148 477.6 35.9 2.6e-15 55.7 0.1 12.2 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 EIM83336.1 - 7.9e-130 423.4 52.1 2.9e-17 62.7 1.3 11.0 2 1 9 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83336.1 - 1.2e-35 118.9 23.8 0.0058 16.6 0.0 11.9 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_17 PF13431.6 EIM83336.1 - 1.1e-29 100.6 4.9 0.37 11.3 0.0 11.1 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_4 PF07721.14 EIM83336.1 - 9e-29 97.1 21.8 0.036 14.7 0.3 10.9 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83336.1 - 2.9e-28 95.6 5.3 0.16 12.1 0.0 11.4 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 EIM83336.1 - 4.4e-21 73.8 4.1 0.77 9.7 0.0 11.0 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83336.1 - 9.9e-18 64.5 15.1 0.065 13.9 0.2 10.3 8 3 2 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 EIM83336.1 - 1.6e-15 57.3 6.9 0.069 13.7 0.0 9.3 3 2 8 11 11 11 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM83336.1 - 5.5e-15 55.6 27.9 1.6e-06 27.8 3.2 4.1 1 1 4 5 5 5 5 MalT-like TPR region TPR_8 PF13181.6 EIM83336.1 - 1.6e-14 52.8 5.6 1.7 9.1 0.0 10.8 12 0 0 12 12 12 1 Tetratricopeptide repeat TetR_C_20 PF17925.1 EIM83336.1 - 6.4e-10 39.3 20.9 0.07 13.5 0.5 7.3 1 1 5 8 8 8 4 Tetracyclin repressor-like, C-terminal domain TPR_3 PF07720.12 EIM83336.1 - 1.4e-08 34.5 0.0 1.2 9.2 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat YqaH PF17448.2 EIM83336.1 - 0.00084 19.6 0.0 49 4.3 0.0 5.4 1 1 2 6 6 6 0 Uncharacterized YqaH-like BAP PF06639.11 EIM83336.1 - 0.0022 18.3 2.5 1.4e+02 2.9 0.0 6.6 5 2 3 8 8 7 0 Basal layer antifungal peptide (BAP) PPR PF01535.20 EIM83336.1 - 0.0038 17.4 1.5 84 3.8 0.0 6.2 7 0 0 7 7 5 0 PPR repeat DUF2508 PF10704.9 EIM83336.1 - 0.094 12.9 0.2 6.4 7.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) TPR_6 PF13174.6 EIM83336.1 - 0.23 12.2 21.4 29 5.6 0.1 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF1743 PF08489.11 EIM83336.1 - 0.24 11.5 4.3 51 4.0 0.1 4.6 3 2 1 4 4 4 0 Domain of unknown function (DUF1743) DUF2018 PF09442.10 EIM83336.1 - 0.4 11.7 3.3 13 6.8 0.0 4.0 4 1 1 5 5 4 0 Domain of unknown function (DUF2018) TPR_14 PF13428.6 EIM83336.1 - 0.49 11.3 25.0 1e+02 4.1 0.0 9.7 11 0 0 11 11 10 0 Tetratricopeptide repeat Neuraminidase PF18413.1 EIM83336.1 - 0.64 9.7 12.2 35 4.0 0.1 5.5 1 1 4 5 5 5 0 Neuraminidase-like domain DUF1543 PF07566.12 EIM83336.1 - 0.79 9.5 10.9 15 5.4 0.0 6.3 7 0 0 7 7 7 0 Domain of Unknown Function (DUF1543) TPR_9 PF13371.6 EIM83336.1 - 0.94 9.7 6.3 4.1 7.6 0.2 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat WAC_Acf1_DNA_bd PF10537.9 EIM83337.1 - 1.9e-35 121.4 1.7 5.5e-35 119.9 1.7 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EIM83337.1 - 5.8e-30 103.7 4.3 1e-29 102.9 0.0 3.3 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EIM83337.1 - 2.1e-14 53.5 0.2 4.7e-13 49.2 0.2 2.4 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 EIM83337.1 - 1.3e-08 34.2 0.0 3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF3287 PF11690.8 EIM83337.1 - 0.12 12.1 2.5 4.2 7.1 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) FAM76 PF16046.5 EIM83337.1 - 0.28 10.5 15.8 0.14 11.5 4.9 2.3 2 0 0 2 2 2 0 FAM76 protein Fungal_trans PF04082.18 EIM83338.1 - 1.4e-08 34.1 0.1 3.3e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM83338.1 - 0.008 16.3 10.5 0.014 15.5 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF6 PF04935.12 EIM83338.1 - 0.022 14.6 0.9 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 Surfeit locus protein 6 Spt4 PF06093.13 EIM83338.1 - 0.42 10.7 1.4 1 9.5 1.4 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Aa_trans PF01490.18 EIM83339.1 - 5.2e-57 193.4 23.1 6.6e-57 193.1 23.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM51 PF15345.6 EIM83339.1 - 0.19 11.6 0.8 3.5 7.4 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Trp_Tyr_perm PF03222.13 EIM83339.1 - 0.83 8.6 22.9 0.009 15.1 14.6 1.9 2 1 0 2 2 2 0 Tryptophan/tyrosine permease family TPR_12 PF13424.6 EIM83340.1 - 3.2e-29 101.0 17.8 1.4e-09 38.1 0.5 5.4 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EIM83340.1 - 1.1e-28 98.2 19.3 9.6e-06 25.3 0.2 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat Patatin PF01734.22 EIM83340.1 - 4.8e-14 53.0 0.1 5.3e-13 49.6 0.0 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase TPR_19 PF14559.6 EIM83340.1 - 2.9e-10 40.5 5.1 0.00014 22.3 0.4 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83340.1 - 6.1e-09 35.3 18.9 0.11 12.7 0.4 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EIM83340.1 - 4.1e-06 26.4 12.4 1 9.3 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83340.1 - 3.4e-05 24.4 19.1 0.0074 16.9 3.2 5.3 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83340.1 - 0.00011 22.1 6.0 1.3 9.4 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM83340.1 - 0.00018 22.1 18.2 3.6 8.6 0.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EIM83340.1 - 0.00041 20.7 15.8 1.4 9.7 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM83340.1 - 0.0013 18.9 10.4 0.23 11.7 0.4 4.8 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIM83340.1 - 0.0038 17.2 13.4 2.9 8.1 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EIM83340.1 - 0.0053 17.1 5.2 18 5.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM83340.1 - 0.12 13.1 13.7 23 5.9 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat DpnD-PcfM PF14207.6 EIM83340.1 - 0.12 12.3 0.2 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 DpnD/PcfM-like protein Cortexin PF11057.8 EIM83341.1 - 0.0023 17.8 0.4 0.0023 17.8 0.4 2.1 1 1 1 2 2 2 1 Cortexin of kidney NICE-3 PF07406.11 EIM83341.1 - 0.0024 17.9 0.1 0.0024 17.9 0.1 2.0 3 0 0 3 3 3 1 NICE-3 protein EptA_B_N PF08019.12 EIM83341.1 - 0.026 14.4 2.2 0.039 13.8 2.2 1.2 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB Shisa PF13908.6 EIM83341.1 - 0.028 14.7 0.5 0.066 13.4 0.0 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 EIM83341.1 - 1.1 10.0 4.0 21 5.8 1.5 2.3 1 1 1 2 2 2 0 WW domain-binding protein 1 DUF2207 PF09972.9 EIM83341.1 - 1.4 7.6 3.4 1.9 7.2 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GST_N_3 PF13417.6 EIM83342.1 - 5.4e-05 23.5 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM83342.1 - 0.0013 19.1 0.0 0.0046 17.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM83342.1 - 0.0088 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM83342.1 - 0.074 13.4 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain FAD_binding_6 PF00970.24 EIM83343.1 - 4.1e-34 116.9 0.0 7.2e-34 116.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EIM83343.1 - 2.3e-31 108.6 0.0 3.6e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EIM83343.1 - 2.3e-06 27.8 0.0 0.00029 21.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EIM83343.1 - 0.0029 17.8 0.0 0.008 16.4 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain PSI_PSAK PF01241.18 EIM83343.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Photosystem I psaG / psaK DSPc PF00782.20 EIM83344.1 - 4.9e-20 71.7 0.0 5.2e-19 68.4 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIM83344.1 - 0.008 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF846 PF05832.12 EIM83345.1 - 8.9e-54 181.3 10.0 1.1e-53 181.0 10.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2207 PF09972.9 EIM83345.1 - 0.35 9.6 3.2 3.4 6.3 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ResIII PF04851.15 EIM83347.1 - 1.1e-18 67.8 0.0 2.8e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM83347.1 - 5.6e-18 65.3 0.0 1.5e-17 63.9 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM83347.1 - 4.5e-16 59.1 0.0 1.3e-15 57.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AA_permease PF00324.21 EIM83348.1 - 6.9e-130 433.8 33.9 7.9e-130 433.6 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM83348.1 - 1.2e-37 129.8 44.0 1.5e-37 129.5 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease UCR_6-4kD PF08997.10 EIM83348.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein AA_permease PF00324.21 EIM83349.1 - 1.1e-134 449.6 34.8 1.3e-134 449.5 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM83349.1 - 4e-37 128.1 41.9 4.8e-37 127.8 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease LRR_4 PF12799.7 EIM83352.1 - 1.1e-05 25.7 15.2 0.075 13.5 0.0 7.3 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EIM83352.1 - 1.5e-05 24.7 0.1 0.39 10.9 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 EIM83352.1 - 0.0014 18.3 10.5 0.51 10.1 0.0 5.9 5 3 1 6 6 6 2 Leucine rich repeat LRR_9 PF14580.6 EIM83352.1 - 0.19 11.2 1.7 21 4.6 0.0 3.4 3 1 1 4 4 4 0 Leucine-rich repeat RhoGEF PF00621.20 EIM83353.1 - 4e-44 151.0 0.0 5.9e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 EIM83353.1 - 3.1e-09 36.5 1.6 8.4e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EIM83353.1 - 3.3e-06 27.3 0.8 0.066 13.7 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) PAXNEB PF05625.11 EIM83354.1 - 3e-53 181.3 0.0 4.2e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein TPR_1 PF00515.28 EIM83355.1 - 1e-06 28.3 1.2 0.029 14.2 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83355.1 - 1.4e-06 28.0 3.3 0.13 12.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83355.1 - 0.03 15.0 2.4 0.81 10.4 0.1 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83355.1 - 0.05 13.6 0.0 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM83355.1 - 0.061 13.6 3.1 2.8 8.3 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83355.1 - 0.13 12.5 1.6 2.5 8.5 0.1 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM83355.1 - 0.13 13.1 0.6 13 6.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S24 PF00717.23 EIM83356.1 - 2.9e-06 27.1 0.0 5.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EIM83356.1 - 1e-05 25.4 0.0 0.0032 17.3 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 adh_short PF00106.25 EIM83357.1 - 1.1e-30 106.5 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM83357.1 - 8.8e-13 48.3 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM83357.1 - 3.8e-08 33.4 0.0 9.3e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 EIM83357.1 - 0.0044 17.3 0.1 0.0074 16.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 EIM83358.1 - 4.7e-28 98.2 0.0 7.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EIM83358.1 - 0.0036 16.6 0.0 0.0059 15.9 0.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SH3_1 PF00018.28 EIM83361.1 - 0.00066 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain hSH3 PF14603.6 EIM83361.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.5 1 1 0 1 1 1 0 Helically-extended SH3 domain SH3_9 PF14604.6 EIM83361.1 - 0.043 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain zf-Tim10_DDP PF02953.15 EIM83362.1 - 1.9e-23 81.9 1.5 2.6e-23 81.4 1.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acyltransferase PF01553.21 EIM83363.1 - 7.8e-23 80.6 0.0 1.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EIM83363.1 - 6.8e-08 32.5 0.3 1.7e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase C-terminus Myb_DNA-binding PF00249.31 EIM83364.1 - 0.64 10.3 3.7 0.3 11.3 0.5 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Peroxidase_2 PF01328.17 EIM83365.1 - 7.8e-47 160.2 0.0 9.4e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 TPR_12 PF13424.6 EIM83366.1 - 9.7e-37 125.1 38.1 5.4e-11 42.6 0.3 6.1 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 EIM83366.1 - 1.4e-36 123.3 25.4 3.5e-07 29.9 0.1 8.2 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83366.1 - 3.2e-10 39.3 10.9 0.66 10.1 0.1 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83366.1 - 3.5e-09 36.1 6.7 0.56 10.6 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83366.1 - 1.3e-08 34.3 6.9 0.24 11.6 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM83366.1 - 1.3e-08 35.2 4.1 0.19 12.3 0.1 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM83366.1 - 3.5e-08 33.6 14.9 0.075 13.3 0.0 6.4 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EIM83366.1 - 7e-08 32.4 10.8 0.13 12.9 0.9 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM83366.1 - 1.4e-07 31.7 4.5 0.58 10.9 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM83366.1 - 2.2e-06 28.0 11.4 1.6 9.8 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIM83366.1 - 4.2e-05 23.2 2.4 0.86 9.5 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83366.1 - 0.003 18.2 12.4 6.7 7.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3660 PF12398.8 EIM83366.1 - 0.0072 16.4 1.1 23 5.2 0.0 5.2 7 0 0 7 7 7 0 Receptor serine/threonine kinase TPR_17 PF13431.6 EIM83366.1 - 0.26 11.8 8.5 48 4.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EIM83366.1 - 2.7 8.4 7.0 5.1 7.5 0.3 3.8 3 2 2 5 5 5 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 EIM83367.1 - 2.6e-19 69.5 0.0 3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM83367.1 - 7.7e-15 55.0 0.0 8.8e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIM83367.1 - 0.015 15.0 0.1 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EIM83367.1 - 0.072 12.4 0.1 0.083 12.2 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM83367.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Hydrolase_4 PF12146.8 EIM83368.1 - 2e-07 30.5 0.0 2.2e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM83368.1 - 8.9e-05 22.2 0.6 0.00029 20.6 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EIM83368.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF1524 PF07510.11 EIM83370.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) Aconitase PF00330.20 EIM83371.1 - 6.6e-148 493.5 0.0 8.5e-148 493.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIM83371.1 - 3.1e-34 118.1 0.0 5.9e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MutS_V PF00488.21 EIM83372.1 - 1.4e-68 230.6 0.0 3.1e-68 229.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIM83372.1 - 1e-38 133.5 3.5 2.1e-38 132.4 3.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EIM83372.1 - 3.1e-22 78.9 0.0 1.2e-21 77.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EIM83372.1 - 1.3e-12 48.2 0.0 3.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 EIM83372.1 - 2.1e-05 24.2 0.0 5.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EIM83372.1 - 0.0001 22.9 0.2 0.014 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EIM83372.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 EIM83372.1 - 0.029 14.4 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EIM83372.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIM83372.1 - 0.19 12.3 0.5 0.86 10.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Septin PF00735.18 EIM83373.1 - 3.9e-110 367.6 0.3 5.7e-110 367.0 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EIM83373.1 - 7.7e-06 26.0 0.0 2.5e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIM83373.1 - 0.0011 18.5 0.1 0.051 13.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EIM83373.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EIM83373.1 - 0.013 15.6 3.5 2.5 8.1 0.0 3.1 2 1 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 EIM83373.1 - 0.024 14.5 3.9 0.069 13.0 0.4 3.1 3 1 0 3 3 3 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EIM83373.1 - 0.047 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 EIM83373.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Gasdermin_C PF17708.1 EIM83373.1 - 0.36 10.9 4.4 0.41 10.8 2.9 1.8 2 0 0 2 2 2 0 Gasdermin PUB domain DUF3543 PF12063.8 EIM83374.1 - 0.0056 16.1 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) MIT PF04212.18 EIM83374.1 - 0.027 14.5 0.0 0.09 12.9 0.0 1.9 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain Glyco_hydro_3_C PF01915.22 EIM83376.1 - 8.9e-44 149.9 0.0 1.5e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM83376.1 - 1.5e-32 113.3 0.0 1.2e-31 110.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM83376.1 - 1.4e-20 73.2 0.0 2.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ChiC PF06483.11 EIM83376.1 - 0.089 12.7 0.1 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Chitinase C Glyco_hydro_3_C PF01915.22 EIM83377.1 - 1.7e-50 171.9 0.1 4e-50 170.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM83377.1 - 3.6e-39 135.0 0.0 5.8e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM83377.1 - 3.7e-19 68.6 0.0 6.7e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.18 EIM83377.1 - 3.5e-10 39.7 10.2 3.5e-10 39.7 10.2 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain DMAP_binding PF06464.11 EIM83377.1 - 0.17 12.7 0.7 20 6.0 0.2 2.6 3 0 0 3 3 3 0 DMAP1-binding Domain Oxysterol_BP PF01237.18 EIM83378.1 - 1.8e-101 339.7 6.1 9.6e-101 337.3 6.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EIM83378.1 - 4.4e-16 58.9 1.8 1.1e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EIM83378.1 - 3.7e-07 30.6 1.0 1.3e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 PH domain 6PGD PF00393.19 EIM83379.1 - 1.5e-126 421.7 0.0 1.9e-126 421.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EIM83379.1 - 1e-49 168.8 0.0 1.5e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EIM83379.1 - 0.0015 18.6 0.2 0.0049 16.9 0.2 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EIM83379.1 - 0.012 16.2 0.1 0.026 15.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 EIM83379.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Asn_synthase PF00733.21 EIM83380.1 - 1.7e-19 70.7 2.1 7.7e-09 35.7 0.1 3.6 2 2 2 4 4 4 3 Asparagine synthase GATase_7 PF13537.6 EIM83380.1 - 5.2e-06 26.4 0.0 1.4e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EIM83380.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain QueC PF06508.13 EIM83380.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Band_7 PF01145.25 EIM83381.1 - 9.6e-24 84.3 5.5 2.5e-23 83.0 5.5 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EIM83381.1 - 0.0014 17.8 3.3 0.0017 17.5 3.3 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial MgtE_N PF03448.17 EIM83381.1 - 0.057 14.0 3.3 0.41 11.3 0.1 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain ORF_12_N PF18042.1 EIM83381.1 - 0.17 12.3 0.9 0.41 11.1 0.6 1.8 1 1 0 1 1 1 0 ORF 12 gene product N-terminal RRM_1 PF00076.22 EIM83382.1 - 2.8e-54 180.8 0.0 7.3e-19 67.4 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM83382.1 - 6.6e-09 35.4 0.0 1.9e-05 24.3 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM83382.1 - 1.5e-06 27.9 0.0 0.00065 19.5 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EIM83382.1 - 0.0011 18.9 0.1 1.8 8.6 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EIM83382.1 - 0.0069 16.4 0.0 4.3 7.5 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 EIM83382.1 - 0.014 15.5 0.0 0.35 11.0 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif NupH_GANP PF16768.5 EIM83382.1 - 2.4 7.8 6.6 4.4 6.9 6.6 1.3 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein GST_N_3 PF13417.6 EIM83383.1 - 6.9e-18 64.8 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM83383.1 - 5.2e-17 62.0 0.0 9.1e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM83383.1 - 6.5e-14 51.9 0.0 9.6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM83383.1 - 5.3e-12 45.9 0.0 8.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM83383.1 - 2e-08 34.1 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM83383.1 - 1e-05 25.6 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ras PF00071.22 EIM83384.1 - 6.5e-58 194.9 0.2 7.6e-58 194.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM83384.1 - 1e-32 112.8 0.0 1.7e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM83384.1 - 3.6e-14 52.6 0.0 4.6e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM83384.1 - 9.9e-08 32.1 0.0 2.1e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIM83384.1 - 3.1e-07 30.0 0.1 3.8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIM83384.1 - 8.1e-07 28.8 0.0 2.4e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIM83384.1 - 4.6e-05 23.4 0.3 0.0045 16.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 EIM83384.1 - 0.0003 20.6 0.4 0.013 15.3 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EIM83384.1 - 0.00041 20.1 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EIM83384.1 - 0.0015 18.2 0.0 0.0053 16.4 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EIM83384.1 - 0.0018 17.6 0.3 0.046 13.0 0.0 2.2 2 1 0 2 2 2 1 Septin AAA_22 PF13401.6 EIM83384.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EIM83384.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EIM83384.1 - 0.013 15.9 0.1 0.032 14.6 0.0 1.7 1 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EIM83384.1 - 0.016 14.9 0.1 0.034 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EIM83384.1 - 0.017 15.1 0.1 0.062 13.3 0.0 1.8 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EIM83384.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EIM83384.1 - 0.023 15.3 0.1 0.93 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EIM83384.1 - 0.045 13.7 0.7 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 EIM83384.1 - 0.047 14.0 0.0 0.09 13.1 0.0 1.5 1 1 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NTPase_1 PF03266.15 EIM83384.1 - 0.055 13.4 0.1 0.093 12.6 0.0 1.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 EIM83384.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EIM83384.1 - 0.28 11.7 1.1 0.54 10.8 1.1 1.8 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.11 EIM83385.1 - 1.2e-51 175.8 23.2 1.2e-51 175.8 23.2 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Rootletin PF15035.6 EIM83385.1 - 0.036 14.1 20.2 1.8 8.6 20.2 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lectin_C PF00059.21 EIM83385.1 - 0.15 12.8 0.5 0.32 11.7 0.5 1.6 1 0 0 1 1 1 0 Lectin C-type domain FlaC_arch PF05377.11 EIM83385.1 - 0.18 12.2 2.9 14 6.2 0.1 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EIM83385.1 - 0.18 12.4 14.3 0.16 12.6 3.4 3.1 2 1 1 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 EIM83385.1 - 0.2 12.1 20.4 1.2 9.7 4.4 3.8 2 1 1 3 3 3 0 Cell division protein ZapB Spc7 PF08317.11 EIM83385.1 - 1.1 8.1 17.1 0.14 11.0 12.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 EIM83385.1 - 1.4 9.4 16.6 18 5.7 13.4 2.4 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 EIM83385.1 - 2.5 8.2 6.0 9.7 6.2 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EIM83385.1 - 6.5 6.9 9.0 5.5 7.2 6.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SOGA PF11365.8 EIM83385.1 - 8.1 7.7 15.7 0.12 13.5 3.5 3.1 2 1 1 3 3 3 0 Protein SOGA Aminotran_4 PF01063.19 EIM83386.1 - 1.7e-30 106.6 0.0 2.5e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV Zn_clus PF00172.18 EIM83387.1 - 2.5e-14 53.1 32.7 2.4e-07 30.7 12.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Connexin40_C PF16791.5 EIM83387.1 - 0.25 12.6 3.2 0.68 11.2 3.2 1.7 1 0 0 1 1 1 0 Connexin 40 C-terminal domain PXA PF02194.15 EIM83390.1 - 8.8e-41 139.9 0.3 1.6e-40 139.0 0.3 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EIM83390.1 - 0.0063 17.1 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Sorting nexin C terminal YGGT PF02325.17 EIM83390.1 - 0.14 12.6 0.4 0.39 11.2 0.4 1.7 1 0 0 1 1 1 0 YGGT family Glyco_hydro_15 PF00723.21 EIM83391.1 - 8.3e-51 173.2 0.0 1.1e-50 172.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Mpv17_PMP22 PF04117.12 EIM83393.1 - 6.9e-22 77.4 0.1 1.2e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Asp PF00026.23 EIM83394.1 - 5.4e-66 223.2 0.7 6.5e-66 222.9 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM83394.1 - 1.2e-12 48.4 7.2 1.1e-08 35.5 5.6 3.3 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM83394.1 - 0.0035 18.0 0.9 0.22 12.2 0.2 2.7 2 1 0 2 2 2 1 Aspartyl protease Amidohydro_1 PF01979.20 EIM83395.1 - 3.7e-37 128.4 0.0 5.4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM83395.1 - 5.8e-17 62.3 0.2 9.6e-13 48.4 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family BTB PF00651.31 EIM83396.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Fcf1 PF04900.12 EIM83399.1 - 2e-34 117.9 0.2 3e-34 117.4 0.2 1.3 1 0 0 1 1 1 1 Fcf1 Nucleo_P87 PF07267.11 EIM83399.1 - 0.23 10.3 2.7 0.28 10.0 2.7 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NAM-associated PF14303.6 EIM83399.1 - 8.2 7.1 9.9 16 6.2 9.9 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pro_CA PF00484.19 EIM83401.1 - 1.4e-13 51.4 0.0 1.9e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF4132 PF13569.6 EIM83401.1 - 0.03 14.1 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) ThiI PF02568.14 EIM83401.1 - 0.092 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NT5C PF06941.12 EIM83402.1 - 3e-11 43.5 0.1 6.5e-11 42.4 0.0 1.6 2 1 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 EIM83402.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ABC_membrane_2 PF06472.15 EIM83403.1 - 2.6e-82 276.3 0.5 3.4e-82 275.9 0.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EIM83403.1 - 7.8e-17 62.1 0.0 1.8e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIM83403.1 - 0.00021 21.2 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIM83403.1 - 0.0062 17.1 0.1 0.016 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EIM83403.1 - 0.047 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIM83403.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EIM83403.1 - 0.091 12.5 0.2 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EIM83403.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4258 PF14076.6 EIM83403.1 - 0.18 12.2 0.0 3.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4258) Ribosomal_S8 PF00410.19 EIM83404.1 - 9.3e-11 41.8 0.0 6.6e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 PRELI PF04707.14 EIM83405.1 - 1.8e-36 125.3 0.0 2.2e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family B-block_TFIIIC PF04182.12 EIM83406.1 - 3.3e-11 43.2 0.8 2e-07 31.0 0.1 3.4 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC MarR_2 PF12802.7 EIM83406.1 - 6.9e-05 22.7 4.7 0.61 10.0 0.0 4.8 4 0 0 4 4 4 2 MarR family HTH_24 PF13412.6 EIM83406.1 - 0.018 14.6 0.1 2.4 7.8 0.0 3.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AHD PF17793.1 EIM83406.1 - 0.045 13.5 0.1 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Myb_DNA-binding PF00249.31 EIM83406.1 - 0.11 12.7 0.2 0.36 11.1 0.2 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain AT_hook PF02178.19 EIM83406.1 - 0.81 9.8 59.4 0.5 10.4 2.4 6.3 5 0 0 5 5 5 0 AT hook motif Lactamase_B_2 PF12706.7 EIM83407.1 - 2.7e-21 76.0 0.0 3.2e-16 59.5 0.0 3.1 2 1 1 3 3 3 3 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM83407.1 - 7.8e-07 29.3 0.8 1.6e-06 28.3 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EIM83407.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain PIN PF01850.21 EIM83407.1 - 0.058 13.9 0.0 2.2 8.8 0.0 2.4 1 1 1 2 2 2 0 PIN domain EssA PF10661.9 EIM83407.1 - 0.27 11.1 2.8 0.43 10.4 2.8 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA VPS13_mid_rpt PF16910.5 EIM83408.1 - 1.2e-98 329.2 13.0 1.1e-96 322.8 1.7 5.1 5 1 1 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EIM83408.1 - 3.6e-84 282.2 0.9 3.7e-79 265.8 0.0 4.0 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EIM83408.1 - 3.9e-69 232.0 6.1 5.4e-65 218.5 0.1 3.0 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EIM83408.1 - 2e-65 220.9 0.0 6.8e-61 206.0 0.0 3.3 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EIM83408.1 - 6.8e-29 100.3 0.1 3e-28 98.3 0.1 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EIM83408.1 - 1.6e-10 41.2 0.0 3.4e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain PUD PF03714.14 EIM83408.1 - 0.19 12.6 2.0 30 5.6 0.1 3.2 2 0 0 2 2 2 0 Bacterial pullanase-associated domain ELO PF01151.18 EIM83410.1 - 3.2e-59 200.5 20.7 3.9e-59 200.2 20.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RasGAP PF00616.19 EIM83411.1 - 2.9e-26 92.5 0.0 2.2e-22 79.8 0.0 2.2 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EIM83411.1 - 9e-09 35.6 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 EIM83411.1 - 0.084 13.4 0.2 0.22 12.1 0.2 1.7 1 0 0 1 1 1 0 PH domain Adaptin_N PF01602.20 EIM83412.1 - 8.4e-124 414.0 4.9 1.2e-123 413.5 4.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EIM83412.1 - 1.4e-40 138.0 0.0 3.3e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EIM83412.1 - 1.1e-13 51.5 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EIM83412.1 - 0.00054 20.0 1.2 0.052 13.6 0.1 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EIM83412.1 - 0.017 15.3 2.1 0.025 14.7 0.4 2.2 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EIM83412.1 - 0.12 12.7 0.9 6.8 7.2 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat HA2 PF04408.23 EIM83413.1 - 1.3e-16 60.9 0.0 2.9e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIM83413.1 - 3e-14 53.3 0.0 1.8e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain dsrm PF00035.26 EIM83413.1 - 2.1e-12 47.5 0.0 1.9e-07 31.7 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 EIM83413.1 - 4e-07 30.0 0.1 7.8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EIM83413.1 - 7e-05 23.2 0.1 0.00017 21.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 EIM83413.1 - 0.0011 19.3 0.1 0.0078 16.6 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.15 EIM83413.1 - 0.01 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EIM83413.1 - 0.017 14.7 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EIM83413.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EIM83413.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ORC6 PF05460.13 EIM83414.1 - 0.0093 15.3 2.0 0.019 14.3 2.0 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) PPP4R2 PF09184.11 EIM83414.1 - 0.02 14.5 17.9 0.035 13.7 17.9 1.3 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 EIM83414.1 - 0.044 12.6 3.5 0.066 12.0 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_3_Rpc31 PF11705.8 EIM83414.1 - 0.083 13.1 13.9 0.14 12.3 13.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ELH PF02323.15 EIM83414.1 - 0.12 11.8 8.9 0.21 11.0 8.9 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor TRAP_alpha PF03896.16 EIM83414.1 - 0.14 11.3 6.5 0.23 10.6 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ashwin PF15323.6 EIM83414.1 - 0.47 10.4 9.8 0.84 9.6 9.8 1.3 1 0 0 1 1 1 0 Developmental protein NOA36 PF06524.12 EIM83414.1 - 1.1 8.6 16.4 1.6 8.0 16.4 1.2 1 0 0 1 1 1 0 NOA36 protein Tub_N PF16322.5 EIM83414.1 - 1.6 9.1 14.2 4.6 7.6 14.2 1.7 1 0 0 1 1 1 0 Tubby N-terminal FYDLN_acid PF09538.10 EIM83414.1 - 1.7 9.3 16.4 3 8.6 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 EIM83414.1 - 2.3 6.4 11.3 3.3 5.9 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EIM83414.1 - 2.7 7.7 20.2 4.7 6.9 20.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EVI2A PF05399.11 EIM83414.1 - 4.4 6.8 10.0 13 5.3 10.0 1.7 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MSP1_C PF07462.11 EIM83414.1 - 5.3 5.6 11.9 7.7 5.1 11.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Nop14 PF04147.12 EIM83414.1 - 5.6 5.1 18.2 7.6 4.6 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.6 EIM83414.1 - 6.9 7.4 9.6 16 6.2 9.6 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Glyco_hydro_16 PF00722.21 EIM83415.1 - 4.5e-07 29.5 0.0 8.8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_49N PF17433.2 EIM83415.1 - 0.012 15.2 0.4 0.023 14.3 0.4 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain ArsA_HSP20 PF17886.1 EIM83416.1 - 7.8e-08 31.8 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EIM83416.1 - 0.00017 21.7 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.11 EIM83416.1 - 0.0015 18.6 0.0 0.0015 18.6 0.0 1.1 1 0 0 1 1 1 1 GvpH SBDS_C PF09377.10 EIM83417.1 - 6.1e-33 113.3 0.0 1.1e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EIM83417.1 - 1.1e-32 111.9 1.3 1.7e-32 111.3 1.3 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein BAR PF03114.18 EIM83418.1 - 1.4e-41 142.7 1.1 1.9e-41 142.3 1.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EIM83418.1 - 2.9e-15 55.6 0.1 4.6e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM83418.1 - 1.1e-13 50.8 0.3 1.8e-13 50.1 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIM83418.1 - 4.6e-09 35.8 0.0 7.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_9 PF08003.11 EIM83418.1 - 0.01 14.8 0.5 0.016 14.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Baculo_PEP_C PF04513.12 EIM83418.1 - 0.15 12.1 0.2 0.85 9.7 0.1 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAP PF07174.11 EIM83418.1 - 4.1 6.8 25.4 6.6 6.1 25.4 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SNF2_N PF00176.23 EIM83419.1 - 4.4e-71 239.4 0.1 1.3e-70 237.9 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EIM83419.1 - 2.2e-20 72.5 0.4 7.1e-20 70.9 0.2 2.0 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 EIM83419.1 - 1.2e-18 67.5 1.7 3.3e-18 66.1 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 EIM83419.1 - 3.9e-17 62.3 10.9 3.9e-17 62.3 10.9 3.1 3 0 0 3 3 3 1 HSA SnAC PF14619.6 EIM83419.1 - 3.6e-13 49.9 1.7 3.6e-13 49.9 1.7 3.6 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 EIM83419.1 - 2.6e-12 46.3 1.9 2.6e-12 46.3 1.9 2.0 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 EIM83419.1 - 1.2e-07 31.9 0.0 5.1e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIM83419.1 - 4.3e-07 29.4 0.0 1.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2706 PF10913.8 EIM83420.1 - 0.052 13.4 1.4 1.3 8.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) TPR_10 PF13374.6 EIM83421.1 - 1.2e-121 393.8 71.0 2.2e-10 40.1 0.1 15.1 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_12 PF13424.6 EIM83421.1 - 4.3e-121 395.4 92.6 1.2e-16 60.8 2.3 11.8 2 2 12 14 14 14 14 Tetratricopeptide repeat TPR_7 PF13176.6 EIM83421.1 - 1.4e-34 115.6 45.7 0.00057 19.7 0.2 14.4 14 0 0 14 14 14 10 Tetratricopeptide repeat TPR_1 PF00515.28 EIM83421.1 - 1.5e-34 116.4 23.7 0.0036 17.0 0.0 14.2 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83421.1 - 7.6e-26 88.1 41.7 0.0091 16.1 0.1 14.2 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 EIM83421.1 - 1.2e-21 76.9 24.8 0.00028 21.3 0.0 10.1 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_4 PF07721.14 EIM83421.1 - 7.5e-20 69.5 42.4 0.062 14.0 0.0 15.1 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM83421.1 - 1.3e-17 62.5 13.2 0.066 13.4 0.0 12.9 14 0 0 14 14 14 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83421.1 - 9e-17 61.4 52.9 0.025 15.2 0.4 13.6 12 3 0 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 EIM83421.1 - 1.2e-13 50.6 43.6 0.62 11.0 0.1 13.9 10 4 5 15 15 14 3 Tetratricopeptide repeat TPR_3 PF07720.12 EIM83421.1 - 3.5e-12 46.1 17.8 0.84 9.7 0.1 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat Ribosomal_L6 PF00347.23 EIM83421.1 - 5.5e-07 30.2 0.0 60 4.4 0.0 8.0 10 0 0 10 10 8 0 Ribosomal protein L6 ANAPC3 PF12895.7 EIM83421.1 - 7.2e-06 26.1 11.4 5.2 7.4 0.0 7.2 5 3 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EIM83421.1 - 0.00018 21.5 10.7 1.5 8.9 0.0 6.3 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EIM83421.1 - 0.00035 20.6 13.3 3.3 7.8 0.1 6.6 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 EIM83421.1 - 0.00053 20.3 27.0 2.7 8.4 0.1 10.7 1 1 7 10 10 10 1 Tetratricopeptide repeat DUF3856 PF12968.7 EIM83421.1 - 0.00054 20.0 8.0 7.5 6.6 0.0 6.8 6 3 1 7 7 5 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 EIM83421.1 - 0.0014 18.7 18.0 11 6.5 0.1 10.5 13 0 0 13 13 13 0 PPR repeat TPR_6 PF13174.6 EIM83421.1 - 0.0016 18.9 31.6 16 6.4 0.0 11.7 14 0 0 14 14 11 0 Tetratricopeptide repeat DUF1925 PF09094.11 EIM83421.1 - 0.0023 18.2 3.6 30 5.0 0.0 6.1 5 1 1 6 6 6 0 Domain of unknown function (DUF1925) TPR_17 PF13431.6 EIM83421.1 - 0.0027 18.0 12.7 1.8 9.1 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_5 PF12688.7 EIM83421.1 - 0.0035 17.6 24.3 0.02 15.1 0.9 6.8 4 3 3 7 7 7 1 Tetratrico peptide repeat Coatomer_E PF04733.14 EIM83421.1 - 0.0049 16.3 11.7 6.1 6.2 0.1 7.1 3 3 4 8 8 8 1 Coatomer epsilon subunit Osmo_CC PF08946.10 EIM83421.1 - 0.018 15.3 11.1 68 3.8 0.0 8.6 9 0 0 9 9 9 0 Osmosensory transporter coiled coil RB_A PF01858.17 EIM83421.1 - 0.024 14.5 6.2 39 4.0 0.1 5.3 4 1 0 5 5 5 0 Retinoblastoma-associated protein A domain PPR_1 PF12854.7 EIM83421.1 - 0.054 13.2 7.1 28 4.5 0.0 6.8 9 0 0 9 9 8 0 PPR repeat DUF2209 PF09974.9 EIM83421.1 - 0.11 12.8 5.6 31 4.9 0.0 6.0 6 2 1 7 7 7 0 Uncharacterized protein conserved in archaea (DUF2209) DUF3326 PF11805.8 EIM83421.1 - 1.1 8.0 4.9 11 4.8 0.0 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3326) YaiA PF16362.5 EIM83421.1 - 7 6.8 15.4 37 4.5 0.0 6.6 9 0 0 9 9 7 0 YaiA protein Es2 PF09751.9 EIM83422.1 - 1.7e-96 324.6 0.9 2.2e-96 324.2 0.9 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Nefa_Nip30_N PF10187.9 EIM83423.1 - 7.2e-25 87.4 14.9 7.2e-25 87.4 14.9 1.7 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Vert_HS_TF PF06546.11 EIM83423.1 - 0.35 10.5 7.3 0.44 10.2 6.8 1.4 1 1 0 1 1 1 0 Vertebrate heat shock transcription factor EamA PF00892.20 EIM83425.1 - 2.6e-10 40.6 31.2 1.5e-06 28.4 3.5 3.1 3 0 0 3 3 3 3 EamA-like transporter family UAA PF08449.11 EIM83425.1 - 0.003 16.8 1.8 0.003 16.8 1.8 2.2 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.16 EIM83425.1 - 0.0084 15.5 1.3 0.0084 15.5 1.3 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family SLC35F PF06027.12 EIM83425.1 - 0.04 13.4 10.2 0.64 9.5 0.0 3.5 3 1 0 4 4 4 0 Solute carrier family 35 GFO_IDH_MocA PF01408.22 EIM83426.1 - 6.9e-15 55.9 0.0 9.4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIM83426.1 - 0.00011 22.8 0.0 0.00015 22.4 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DDE_1 PF03184.19 EIM83427.1 - 1.2e-12 47.9 0.0 1.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease APH PF01636.23 EIM83428.1 - 1.3e-05 25.2 0.2 2.5e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM83428.1 - 3.1e-05 23.5 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIM83428.1 - 4.7e-05 23.1 0.3 0.00012 21.8 0.1 1.5 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.11 EIM83428.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 EIM83428.1 - 0.0023 17.3 0.3 0.013 14.8 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM83428.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EIM83428.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SLX9 PF15341.6 EIM83429.1 - 6.3e-21 75.1 3.1 7.1e-21 75.0 3.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Golgin_A5 PF09787.9 EIM83430.1 - 0.00011 21.7 14.9 0.00011 21.7 14.9 2.2 2 0 0 2 2 2 1 Golgin subfamily A member 5 WD40_alt PF14077.6 EIM83430.1 - 0.024 14.5 0.6 3.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif ApoO PF09769.9 EIM83430.1 - 0.03 14.3 1.0 0.092 12.7 1.0 1.9 2 0 0 2 2 2 0 Apolipoprotein O HAP1_N PF04849.13 EIM83430.1 - 0.26 10.4 24.8 15 4.6 0.0 3.2 3 0 0 3 3 3 0 HAP1 N-terminal conserved region HAUS-augmin3 PF14932.6 EIM83430.1 - 0.27 10.8 27.8 0.18 11.4 1.6 4.0 3 1 1 4 4 4 0 HAUS augmin-like complex subunit 3 Aminopep PF10023.9 EIM83430.1 - 0.41 9.9 9.1 0.69 9.2 9.1 1.3 1 0 0 1 1 1 0 Putative aminopeptidase DUF4201 PF13870.6 EIM83430.1 - 0.44 10.3 22.5 0.36 10.6 11.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) FapA PF03961.13 EIM83430.1 - 7.3 5.1 10.7 1.8 7.1 5.5 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Rad51 PF08423.11 EIM83431.1 - 0.00014 21.2 0.0 0.00038 19.8 0.0 1.8 1 1 0 1 1 1 1 Rad51 AMP-binding PF00501.28 EIM83432.1 - 3.7e-23 81.8 0.0 5.4e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 EIM83432.1 - 0.0033 16.4 0.1 0.0075 15.2 0.1 1.5 1 0 0 1 1 1 1 GH3 auxin-responsive promoter PPR_2 PF13041.6 EIM83433.1 - 3.1e-26 91.3 0.0 1.2e-06 28.6 0.0 6.0 5 0 0 5 5 5 4 PPR repeat family PPR_3 PF13812.6 EIM83433.1 - 2.5e-19 69.1 0.0 1.2e-06 28.5 0.0 4.8 3 1 0 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.20 EIM83433.1 - 1e-14 53.6 0.0 0.00034 20.7 0.0 5.8 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.7 EIM83433.1 - 1.3e-12 47.2 0.0 3.4e-05 23.5 0.0 5.3 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 EIM83433.1 - 9.1e-10 38.3 1.3 6.5e-05 22.4 0.1 3.8 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EIM83433.1 - 0.00015 22.3 11.3 17 6.6 0.1 6.4 6 1 1 7 7 5 0 Tetratricopeptide repeat MRP-S27 PF10037.9 EIM83433.1 - 0.00016 20.7 0.3 2.4 7.0 0.0 3.9 5 0 0 5 5 5 2 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 EIM83433.1 - 0.0018 18.8 5.6 7.6 7.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM83433.1 - 0.034 14.8 1.4 26 5.6 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Coat_F PF07875.12 EIM83433.1 - 0.13 12.5 0.8 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Coat F domain TPR_4 PF07721.14 EIM83433.1 - 8.8 7.3 13.7 1.2 9.9 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EIM83434.1 - 6.4e-46 157.1 25.1 9e-44 150.1 25.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM83434.1 - 1e-15 57.6 38.4 2.6e-09 36.5 22.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 EIM83434.1 - 0.0081 16.4 17.5 0.035 14.4 0.7 4.1 3 1 1 4 4 4 2 Putative inner membrane exporter, YdcZ DUF5336 PF17270.2 EIM83434.1 - 0.041 13.5 0.8 0.11 12.1 0.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5336) SLS PF14611.6 EIM83435.1 - 5.3e-10 39.5 0.0 9.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.12 EIM83436.1 - 2.1e-80 269.3 25.5 2.1e-80 269.3 25.5 4.4 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EIM83436.1 - 2.5e-56 190.6 0.8 2.8e-55 187.2 0.0 2.6 3 0 0 3 3 3 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EIM83436.1 - 2.5e-45 154.2 6.5 2.5e-45 154.2 6.5 6.2 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) Lar_N PF09861.9 EIM83436.1 - 1 8.5 5.5 0.21 10.7 0.4 2.1 2 0 0 2 2 2 0 Lactate racemase N-terminal domain DUF423 PF04241.15 EIM83437.1 - 1.2e-18 67.1 1.7 1.6e-18 66.7 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF4680 PF15730.5 EIM83438.1 - 0.01 16.2 3.7 0.043 14.2 3.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Acetyltransf_3 PF13302.7 EIM83439.1 - 6.5e-15 56.0 0.1 2.3e-14 54.2 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM83439.1 - 2.3e-05 24.6 0.0 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EIM83439.1 - 0.012 15.3 0.1 0.04 13.6 0.1 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain SUR7 PF06687.12 EIM83440.1 - 3.7e-19 69.2 16.3 5.4e-19 68.7 16.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF996 PF06195.13 EIM83440.1 - 1.3 9.3 9.2 6.2 7.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Arginase PF00491.21 EIM83442.1 - 3.7e-84 282.6 0.2 4.6e-84 282.2 0.2 1.1 1 0 0 1 1 1 1 Arginase family WD40 PF00400.32 EIM83443.1 - 2.5e-11 43.9 25.9 0.011 16.6 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat WD40 PF00400.32 EIM83444.1 - 1.6e-31 107.8 20.8 5.1e-06 27.1 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM83444.1 - 2.9e-15 56.3 2.5 0.0059 16.9 0.0 6.1 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM83444.1 - 4.9e-06 26.5 0.0 0.003 17.5 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EIM83444.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 LisH PD40 PF07676.12 EIM83444.1 - 0.0072 16.2 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EIM83444.1 - 0.015 14.0 0.1 4.8 5.7 0.1 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Bax1-I PF01027.20 EIM83445.1 - 3.8e-38 131.4 8.0 3.8e-38 131.4 8.0 1.3 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 HEAT_EZ PF13513.6 EIM83446.1 - 0.0024 18.3 1.1 1.5 9.4 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat Arm PF00514.23 EIM83446.1 - 0.0026 17.8 0.0 0.0026 17.8 0.0 4.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EIM83446.1 - 0.015 15.7 0.0 0.81 10.1 0.0 3.0 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 EIM83446.1 - 0.2 12.0 3.1 13 6.3 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat RIX1 PF08167.12 EIM83446.1 - 0.32 10.7 4.6 0.62 9.8 0.1 3.2 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis OsmC PF02566.19 EIM83447.1 - 1.2e-05 25.7 0.0 1.7e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein Ldh_2 PF02615.14 EIM83448.1 - 2.2e-109 365.7 1.0 2.5e-109 365.5 1.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Vpu PF00558.19 EIM83449.1 - 1.3 8.8 2.8 0.46 10.3 0.1 1.6 2 0 0 2 2 2 0 Vpu protein Sin3a_C PF16879.5 EIM83450.1 - 3.3e-79 266.6 0.0 3.4e-78 263.3 0.0 2.5 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 EIM83450.1 - 6.4e-34 115.9 7.8 1.2e-17 63.8 0.0 3.9 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EIM83450.1 - 9.4e-34 115.4 0.0 1.9e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor SH3_1 PF00018.28 EIM83455.1 - 3.6e-11 42.5 0.1 6.6e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM83455.1 - 2.5e-08 33.6 0.0 6.4e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EIM83455.1 - 4e-08 32.8 0.0 9.4e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4 PF00097.25 EIM83456.1 - 3.3e-10 39.7 5.6 9.8e-10 38.2 5.9 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM83456.1 - 5.3e-08 32.8 10.1 1.3e-07 31.5 7.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EIM83456.1 - 5.4e-07 29.9 10.7 8.9e-07 29.2 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM83456.1 - 1.3e-06 28.1 9.0 1e-05 25.2 9.6 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM83456.1 - 5.8e-06 26.1 6.0 8.7e-06 25.5 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM83456.1 - 5.3e-05 23.3 10.7 9.2e-05 22.5 10.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EIM83456.1 - 0.00015 21.6 7.7 0.00029 20.7 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM83456.1 - 0.0025 17.6 7.0 0.0079 16.0 7.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EIM83456.1 - 0.024 14.4 7.0 0.071 12.9 7.0 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EIM83456.1 - 0.043 14.1 6.9 0.088 13.1 6.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EIM83456.1 - 0.089 12.6 8.4 1.2 8.9 5.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-MIZ PF02891.20 EIM83456.1 - 0.1 12.4 8.3 0.21 11.4 8.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TerY_C PF15616.6 EIM83456.1 - 0.17 12.0 2.3 0.33 11.1 2.3 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-ANAPC11 PF12861.7 EIM83456.1 - 0.66 10.1 5.3 1.2 9.2 5.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1178 PF06676.11 EIM83456.1 - 1.3 9.4 5.8 3.7 7.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) Wbp11 PF09429.10 EIM83457.1 - 1.2e-23 83.3 10.2 2.6e-23 82.2 10.2 1.6 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 EIM83457.1 - 8.3e-13 48.9 20.3 8.3e-13 48.9 20.3 7.6 3 2 0 3 3 3 1 mRNA biogenesis factor Antimicrobial18 PF08130.11 EIM83457.1 - 0.18 11.9 1.4 0.81 9.8 0.4 2.2 2 0 0 2 2 2 0 Type A lantibiotic family Osmo_CC PF08946.10 EIM83457.1 - 0.45 10.8 3.2 2 8.7 3.2 2.0 1 1 0 1 1 1 0 Osmosensory transporter coiled coil YqfD PF06898.11 EIM83457.1 - 1.3 7.8 3.6 1.8 7.3 3.6 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Med21 PF11221.8 EIM83457.1 - 1.5 9.0 9.1 0.11 12.7 3.5 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex HIT PF01230.23 EIM83459.1 - 1.8e-22 79.9 0.0 2.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EIM83459.1 - 7e-06 26.5 0.0 9.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ku_PK_bind PF08785.11 EIM83460.1 - 2.8e-24 85.6 0.1 1.2e-23 83.5 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.16 EIM83460.1 - 1.2e-19 70.8 0.1 5.6e-19 68.7 0.1 2.0 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EIM83460.1 - 0.00011 22.1 0.0 0.0013 18.5 0.0 2.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EIM83460.1 - 0.0005 20.7 0.3 0.0005 20.7 0.3 2.9 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm EamA PF00892.20 EIM83461.1 - 0.0017 18.5 6.9 0.0017 18.5 6.9 3.6 4 0 0 4 4 4 1 EamA-like transporter family CSG2 PF16965.5 EIM83461.1 - 0.79 8.6 11.2 1.8 7.4 11.2 1.8 1 1 0 1 1 1 0 Ceramide synthase regulator Ribosomal_L36 PF00444.18 EIM83462.1 - 5.6e-18 64.9 9.0 8.4e-18 64.3 9.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 zf-C3HC4_2 PF13923.6 EIM83464.1 - 2.8e-10 39.9 8.0 4.8e-10 39.1 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM83464.1 - 6.4e-09 36.0 8.1 1.3e-08 35.0 8.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM83464.1 - 1.2e-08 34.6 5.6 2.2e-08 33.8 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM83464.1 - 3.6e-08 33.1 4.4 7.7e-08 32.1 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM83464.1 - 1.5e-06 28.1 6.7 1.5e-06 28.1 5.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIM83464.1 - 1.5e-05 24.8 5.7 3e-05 23.9 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM83464.1 - 2.5e-05 24.0 2.2 2.5e-05 24.0 2.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EIM83464.1 - 0.00054 20.0 8.5 0.0013 18.8 8.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EIM83464.1 - 0.0071 16.6 10.5 0.073 13.4 10.8 2.3 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-CCCH_6 PF18585.1 EIM83464.1 - 0.061 13.2 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 zf-Nse PF11789.8 EIM83464.1 - 0.075 12.9 1.7 0.16 11.8 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn-ribbon_8 PF09723.10 EIM83464.1 - 0.17 12.1 2.9 0.45 10.7 1.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-ANAPC11 PF12861.7 EIM83464.1 - 0.19 11.8 3.6 0.4 10.8 3.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EIM83464.1 - 0.22 11.7 4.3 0.45 10.7 4.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 ComA PF02679.15 EIM83466.1 - 5.3e-77 258.6 0.0 6e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Glyco_hydro_18 PF00704.28 EIM83467.1 - 2.5e-20 73.5 2.1 7.3e-20 71.9 2.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 EIM83467.1 - 0.3 11.8 17.5 0.57 10.9 4.3 3.5 3 0 0 3 3 3 0 Carbohydrate binding domain CBM_5_12_2 PF14600.6 EIM83467.1 - 1.7 8.7 25.1 0.043 13.8 6.0 3.5 3 0 0 3 3 3 0 Cellulose-binding domain Pkinase PF00069.25 EIM83468.1 - 5.6e-65 219.3 0.1 6.7e-65 219.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83468.1 - 6.3e-20 71.6 0.0 8.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM83468.1 - 1.7e-06 28.2 0.4 4.8e-05 23.4 0.9 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM83468.1 - 0.0045 15.8 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EIM83468.1 - 0.04 13.3 0.2 0.065 12.6 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM83468.1 - 0.057 12.7 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EIM83468.1 - 0.073 12.6 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase SET PF00856.28 EIM83469.1 - 3.2e-09 37.4 0.0 1.2e-07 32.3 0.0 2.1 1 1 0 1 1 1 1 SET domain DnaJ_C PF01556.18 EIM83470.1 - 9.1e-37 126.4 0.0 1.2e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIM83470.1 - 4.2e-22 78.1 4.2 6.4e-22 77.5 4.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIM83470.1 - 2e-10 40.9 17.8 3.4e-10 40.1 17.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EIM83470.1 - 0.0072 16.3 12.5 0.24 11.4 1.6 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EIM83470.1 - 4.6 7.3 9.3 82 3.3 7.0 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MFS_1 PF07690.16 EIM83471.1 - 1.1e-40 139.7 39.7 2.9e-40 138.3 37.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM83471.1 - 1.7e-12 46.9 5.2 1.7e-12 46.9 5.2 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EIM83471.1 - 1.5e-11 43.5 9.3 2.2e-11 42.9 8.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.8 EIM83471.1 - 0.45 10.8 4.9 1 9.6 0.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) Claudin_2 PF13903.6 EIM83471.1 - 2.8 7.7 16.5 0.28 10.9 2.2 4.0 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF3400 PF11880.8 EIM83472.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Choline_kinase PF01633.20 EIM83473.1 - 3.5e-52 177.1 0.0 4.9e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EIM83473.1 - 6.6e-15 55.7 0.0 9.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EIM83473.1 - 1.9e-05 24.2 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase zf-CCCH PF00642.24 EIM83474.1 - 7.2e-19 67.2 14.3 7.8e-11 41.6 2.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIM83474.1 - 4.8e-09 36.0 12.9 1.6e-06 28.0 3.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EIM83474.1 - 5.3e-08 32.5 11.7 3.7e-05 23.4 1.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EIM83474.1 - 0.016 15.6 9.7 0.022 15.2 0.5 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EIM83474.1 - 0.1 13.3 8.8 0.93 10.2 1.6 2.8 1 1 1 2 2 2 0 Torus domain BLM10_mid PF16507.5 EIM83475.1 - 2.9e-188 626.8 0.0 7.9e-188 625.4 0.0 1.8 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EIM83475.1 - 1.6e-31 108.1 0.0 2.9e-30 104.0 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 EIM83475.1 - 1.5e-06 27.9 0.4 0.0014 18.7 0.1 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EIM83475.1 - 0.00051 20.4 0.5 0.022 15.1 0.0 4.1 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 EIM83475.1 - 0.0012 19.3 0.1 0.31 11.6 0.0 4.1 3 0 0 3 3 3 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EIM83475.1 - 0.0047 17.5 0.2 0.039 14.6 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region MatE PF01554.18 EIM83475.1 - 0.093 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 MatE Chalcone_2 PF16035.5 EIM83476.1 - 4.7e-27 95.1 0.1 4.4e-16 59.3 0.0 2.4 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 EIM83476.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.4 1 1 0 1 1 1 0 Chalcone isomerase-like AIM24 PF01987.17 EIM83476.1 - 0.21 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 DUF1516 PF07457.11 EIM83477.1 - 0.011 15.9 0.1 0.011 15.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DUF1275 PF06912.11 EIM83477.1 - 0.057 13.3 0.9 0.64 9.9 0.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) SirB PF04247.12 EIM83477.1 - 0.4 10.8 5.4 0.098 12.7 1.3 2.0 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MIG-14_Wnt-bd PF06664.12 EIM83477.1 - 0.45 9.7 11.2 1.3 8.2 2.4 2.5 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Na_Ca_ex PF01699.24 EIM83477.1 - 1.7 8.6 7.6 3.7 7.5 2.5 2.7 2 1 0 2 2 2 0 Sodium/calcium exchanger protein zf-RING_2 PF13639.6 EIM83478.1 - 2.3e-05 24.6 6.2 3.8e-05 23.9 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EIM83478.1 - 7.3e-05 22.6 6.8 0.00014 21.6 6.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM83478.1 - 0.00016 21.5 6.8 0.0004 20.2 6.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM83478.1 - 0.0026 17.7 6.2 0.0068 16.3 6.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain YabA PF06156.13 EIM83478.1 - 0.012 16.3 13.9 0.71 10.5 6.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA HOOK PF05622.12 EIM83478.1 - 0.036 12.2 19.5 0.047 11.8 19.5 1.0 1 0 0 1 1 1 0 HOOK protein zf-C3HC4_4 PF15227.6 EIM83478.1 - 0.039 14.1 1.9 0.039 14.1 1.9 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EIM83478.1 - 0.05 13.5 9.6 0.17 11.8 9.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM83478.1 - 0.081 13.0 3.5 0.15 12.2 3.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EIM83478.1 - 0.13 12.3 3.0 0.56 10.3 3.1 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EIM83478.1 - 0.23 11.3 6.7 0.6 10.0 6.7 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TMF_DNA_bd PF12329.8 EIM83478.1 - 0.42 10.6 26.8 0.088 12.8 12.2 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.6 EIM83478.1 - 0.46 10.5 25.4 0.47 10.4 3.4 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DHODB_Fe-S_bind PF10418.9 EIM83478.1 - 0.46 10.3 3.4 1 9.2 3.4 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B zf-rbx1 PF12678.7 EIM83478.1 - 0.72 10.2 8.0 2 8.7 8.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain V_ATPase_I PF01496.19 EIM83478.1 - 0.96 7.3 9.7 7 4.4 11.3 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4629 PF15442.6 EIM83478.1 - 1.3 9.3 13.4 2.7 8.2 13.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) zf-RING_4 PF14570.6 EIM83478.1 - 1.4 8.8 9.3 4 7.3 9.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain LCD1 PF09798.9 EIM83478.1 - 1.7 7.0 7.0 2.2 6.7 7.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein TSC22 PF01166.18 EIM83478.1 - 3.4 8.1 9.1 7.1 7.0 2.6 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Csm1_N PF18504.1 EIM83478.1 - 3.8 7.9 19.5 0.11 12.9 9.0 2.7 2 1 1 3 3 2 0 Csm1 N-terminal domain ZapB PF06005.12 EIM83478.1 - 5 7.7 25.4 2.5 8.6 5.8 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 EIM83478.1 - 5.7 7.2 22.6 16 5.7 22.2 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 EIM83478.1 - 7.5 6.7 27.4 20 5.3 2.2 2.1 1 1 1 2 2 2 0 Tropomyosin like Leu_zip PF15294.6 EIM83478.1 - 7.7 5.9 20.6 5.6 6.4 9.5 2.2 1 1 1 2 2 2 0 Leucine zipper TIM21 PF08294.11 EIM83479.1 - 1.1e-21 77.3 0.0 4.2e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 TIM21 SGT1 PF07093.11 EIM83480.1 - 3.4e-99 332.9 20.2 5.1e-64 216.7 1.0 3.7 4 0 0 4 4 4 3 SGT1 protein Host_attach PF10116.9 EIM83480.1 - 0.8 10.3 3.9 4.8 7.8 0.3 2.9 3 0 0 3 3 3 0 Protein required for attachment to host cells Clat_adaptor_s PF01217.20 EIM83481.1 - 4.2e-43 146.7 0.9 8e-43 145.8 0.9 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.14 EIM83482.1 - 3.7e-40 136.8 0.4 6e-40 136.1 0.4 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component GREB1 PF15782.5 EIM83482.1 - 3.6 4.6 7.1 4.4 4.3 7.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nramp PF01566.18 EIM83483.1 - 1.9e-83 280.4 19.5 3e-43 148.2 7.9 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Ribophorin_II PF05817.14 EIM83483.1 - 0.03 12.9 1.2 0.047 12.2 1.2 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Catalase PF00199.19 EIM83484.1 - 4.8e-172 572.4 0.0 6.2e-172 572.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EIM83484.1 - 1.5e-18 66.8 0.1 3.2e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EIM83484.1 - 6.8e-13 48.5 0.0 2.2e-12 46.9 0.0 1.9 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EIM83484.1 - 3.1e-08 33.6 0.0 5.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2 PF00096.26 EIM83485.1 - 2.2e-08 34.1 19.9 7.2e-06 26.2 1.5 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM83485.1 - 1.7e-07 31.5 15.0 0.0005 20.7 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIM83485.1 - 0.0014 18.6 0.3 0.0014 18.6 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger TRAF6_Z2 PF18048.1 EIM83485.1 - 0.0024 17.9 1.5 0.0067 16.5 1.5 1.8 1 0 0 1 1 1 1 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_11 PF16622.5 EIM83485.1 - 0.0066 16.2 6.7 0.8 9.5 0.1 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 EIM83485.1 - 0.0069 16.8 13.6 0.12 12.9 1.4 3.6 4 0 0 4 4 3 2 Zinc-finger double domain zf_ZIC PF18366.1 EIM83485.1 - 0.017 15.2 1.1 4 7.6 0.1 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-Di19 PF05605.12 EIM83485.1 - 0.061 13.6 4.7 0.31 11.4 4.9 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EIM83485.1 - 0.2 12.0 8.2 0.14 12.4 1.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HypA PF01155.19 EIM83485.1 - 0.66 10.0 2.7 14 5.8 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_5 PF13909.6 EIM83485.1 - 5.5 6.8 7.9 41 4.0 3.7 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain MCM PF00493.23 EIM83486.1 - 1.1e-103 345.2 0.0 2.4e-103 344.1 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EIM83486.1 - 2.5e-33 114.6 0.0 5.1e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIM83486.1 - 8.3e-27 93.4 0.3 1.8e-26 92.4 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIM83486.1 - 3.4e-15 56.5 0.1 9.4e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIM83486.1 - 1.4e-06 27.9 0.0 0.00039 19.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIM83486.1 - 0.0002 21.4 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EIM83486.1 - 0.00038 20.3 0.1 0.0019 18.0 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MitMem_reg PF13012.6 EIM83487.1 - 9.5e-28 96.9 0.0 1.6e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EIM83487.1 - 3.7e-11 43.0 0.0 6.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease F-box PF00646.33 EIM83488.1 - 0.002 17.9 0.1 0.002 17.9 0.1 1.9 2 0 0 2 2 2 1 F-box domain zf-CCHH PF10283.9 EIM83488.1 - 0.12 12.4 5.2 0.2 11.7 5.2 1.4 1 0 0 1 1 1 0 PBZ domain DUF4149 PF13664.6 EIM83489.1 - 1e-21 77.2 4.6 1e-21 77.2 4.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) LRR_9 PF14580.6 EIM83490.1 - 1.5e-62 210.1 0.4 3e-62 209.2 0.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EIM83490.1 - 7.5e-10 38.9 11.4 2.7e-06 27.6 4.5 3.8 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM83490.1 - 1.3e-08 34.5 2.5 1.3e-08 34.5 2.5 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 EIM83490.1 - 0.075 13.1 4.7 0.93 9.7 0.4 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Syja_N PF02383.18 EIM83491.1 - 1.1e-86 291.1 0.0 1.4e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain PPP4R2 PF09184.11 EIM83492.1 - 7.3 6.1 19.1 10 5.6 19.1 1.1 1 0 0 1 1 1 0 PPP4R2 VASt PF16016.5 EIM83493.1 - 2.4e-39 135.2 0.1 3.8e-39 134.6 0.1 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EIM83493.1 - 2.9e-20 72.2 0.0 5.6e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Pkinase PF00069.25 EIM83494.1 - 1.5e-62 211.3 0.0 3e-62 210.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83494.1 - 1.5e-25 90.0 0.0 7.1e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EIM83494.1 - 0.00016 22.3 5.6 0.00016 22.3 5.6 3.4 3 0 0 3 3 3 1 Protein kinase C terminal domain PX PF00787.24 EIM83494.1 - 0.00099 19.1 0.0 0.028 14.4 0.1 2.8 2 0 0 2 2 2 1 PX domain FTA2 PF13095.6 EIM83494.1 - 0.0031 17.2 0.0 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIM83494.1 - 0.0073 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM83494.1 - 0.068 13.1 2.0 9.5 6.1 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM83494.1 - 0.079 12.3 0.0 4.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EIM83494.1 - 0.13 11.0 0.0 0.13 11.0 0.0 3.0 4 0 0 4 4 4 0 Fungal protein kinase FPN1 PF06963.12 EIM83495.1 - 0.29 9.6 0.1 0.4 9.2 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Malic_M PF03949.15 EIM83496.1 - 8.1e-85 284.2 0.0 1.2e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EIM83496.1 - 4.6e-57 192.8 0.0 6.6e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ACP_PD PF04336.12 EIM83496.1 - 0.091 13.2 1.6 0.15 12.5 0.5 1.9 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Nop10p PF04135.12 EIM83497.1 - 1.2e-20 73.2 0.3 1.5e-20 73.0 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CRAL_TRIO PF00650.20 EIM83498.1 - 1.9e-39 134.9 0.0 2.5e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIM83498.1 - 7.4e-06 26.1 0.1 1.4e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EIM83498.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Flavin_Reduct PF01613.18 EIM83500.1 - 7.5e-16 58.5 0.0 1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain HATPase_c PF02518.26 EIM83501.1 - 5.8e-29 100.9 0.0 1.9e-28 99.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM83501.1 - 2.3e-19 69.6 0.0 8.6e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 EIM83501.1 - 9.9e-16 58.6 1.2 9.9e-14 52.1 0.5 3.3 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 EIM83501.1 - 9.8e-14 51.2 0.0 3.8e-13 49.3 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 EIM83501.1 - 2.6e-10 40.1 0.0 4.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 EIM83501.1 - 5.9e-08 33.4 0.0 1.9e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 EIM83501.1 - 8.4e-08 31.8 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.12 EIM83501.1 - 0.0071 16.3 0.2 0.027 14.4 0.2 2.1 1 1 0 1 1 1 1 NACHT domain GAF_3 PF13492.6 EIM83501.1 - 0.0099 16.2 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 EIM83501.1 - 0.019 14.8 0.0 0.054 13.3 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DEAD PF00270.29 EIM83502.1 - 6.7e-37 126.9 0.1 1.1e-36 126.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM83502.1 - 1.5e-25 89.7 0.1 3.1e-24 85.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM83502.1 - 2.6e-08 34.1 0.0 4.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 EIM83503.1 - 2.2e-52 175.0 0.9 2.3e-18 65.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Med3 PF11593.8 EIM83504.1 - 0.11 11.6 11.9 0.15 11.3 11.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hamartin PF04388.12 EIM83504.1 - 1.5 7.4 8.4 1.7 7.2 8.4 1.0 1 0 0 1 1 1 0 Hamartin protein SPX PF03105.19 EIM83504.1 - 8.4 6.2 9.5 9.4 6.0 9.5 1.1 1 0 0 1 1 1 0 SPX domain DEAD PF00270.29 EIM83505.1 - 2.9e-37 128.1 0.1 4.4e-37 127.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM83505.1 - 3.6e-22 78.8 0.0 1.2e-21 77.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM83505.1 - 4.1e-06 26.9 0.1 8.5e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.10 EIM83505.1 - 0.021 15.2 15.5 0.057 13.8 15.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EIM83505.1 - 0.037 13.4 11.5 0.07 12.4 11.5 1.4 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 EIM83505.1 - 0.75 9.6 7.2 0.32 10.8 3.4 2.0 2 0 0 2 2 2 0 Myc amino-terminal region TLP-20 PF06088.11 EIM83505.1 - 1.4 8.8 5.1 2.8 7.8 5.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 EIM83505.1 - 2.6 7.7 14.1 0.044 13.4 4.9 2.3 2 1 1 3 3 3 0 FAM176 family DNA_pol_phi PF04931.13 EIM83505.1 - 7 4.6 17.5 12 3.9 17.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 EIM83505.1 - 9.7 6.4 26.2 0.52 10.5 16.1 2.7 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Mg_trans_NIPA PF05653.14 EIM83506.1 - 2.4e-19 69.6 14.4 1.1e-11 44.4 2.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EIM83506.1 - 0.0061 16.7 7.2 0.0061 16.7 7.2 3.1 3 0 0 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 EIM83506.1 - 0.54 9.4 7.1 0.31 10.2 2.7 2.3 1 1 0 2 2 2 0 Purine nucleobase transmembrane transport AAA_2 PF07724.14 EIM83507.1 - 1e-51 175.4 0.0 6e-47 159.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EIM83507.1 - 5e-32 109.9 1.0 5e-32 109.9 1.0 3.3 3 1 1 4 4 2 1 AAA lid domain AAA PF00004.29 EIM83507.1 - 1.9e-24 86.6 0.0 2.7e-13 50.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EIM83507.1 - 3.2e-24 84.8 2.6 3.9e-24 84.5 0.3 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EIM83507.1 - 7.2e-17 61.3 10.1 7.2e-12 45.2 0.3 4.0 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EIM83507.1 - 1.6e-14 54.1 0.0 2.4e-07 30.9 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIM83507.1 - 9e-12 45.7 4.9 2.8e-06 27.8 0.0 5.1 5 1 0 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 EIM83507.1 - 5.3e-08 33.2 0.1 0.047 14.0 0.0 4.6 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EIM83507.1 - 8e-08 32.2 0.0 0.0001 22.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EIM83507.1 - 2.7e-06 27.2 0.0 0.0032 17.2 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EIM83507.1 - 1.2e-05 24.8 0.0 0.014 14.8 0.0 2.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EIM83507.1 - 1.9e-05 24.2 0.0 0.05 13.0 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 EIM83507.1 - 2.2e-05 24.3 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EIM83507.1 - 2.7e-05 24.7 0.0 0.081 13.5 0.0 3.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EIM83507.1 - 4.2e-05 22.9 0.5 0.26 10.5 0.0 3.1 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 EIM83507.1 - 0.00021 21.5 0.0 0.28 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIM83507.1 - 0.00031 21.1 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 EIM83507.1 - 0.00058 19.7 0.3 3.8 7.2 0.0 4.0 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EIM83507.1 - 0.001 18.6 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EIM83507.1 - 0.0018 18.2 0.0 0.52 10.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 EIM83507.1 - 0.0023 17.2 0.8 0.22 10.8 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin ABC_tran PF00005.27 EIM83507.1 - 0.0035 17.9 0.7 2.9 8.4 0.0 3.5 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 EIM83507.1 - 0.0036 17.5 0.0 0.5 10.6 0.0 3.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EIM83507.1 - 0.0048 16.9 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EIM83507.1 - 0.0049 16.9 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EIM83507.1 - 0.009 15.5 0.0 1.3 8.4 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 EIM83507.1 - 0.024 14.9 4.4 1.3 9.2 0.0 3.6 3 1 0 3 3 2 0 AAA domain FACT-Spt16_Nlob PF14826.6 EIM83507.1 - 0.027 14.3 0.0 0.094 12.5 0.0 1.8 2 0 0 2 2 1 0 FACT complex subunit SPT16 N-terminal lobe domain ResIII PF04851.15 EIM83507.1 - 0.029 14.4 0.0 2.3 8.2 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EIM83507.1 - 0.03 14.0 0.1 10 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain Torsin PF06309.11 EIM83507.1 - 0.044 13.9 0.0 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 Torsin RsgA_GTPase PF03193.16 EIM83507.1 - 0.048 13.6 0.0 4.7 7.1 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 EIM83507.1 - 0.057 13.7 1.7 7.1 6.9 0.0 3.9 5 0 0 5 5 3 0 AAA domain CbiA PF01656.23 EIM83507.1 - 0.077 13.0 0.1 11 6.1 0.0 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 EIM83507.1 - 0.098 12.5 6.5 2.9 7.7 0.1 4.3 3 2 1 4 4 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EIM83507.1 - 0.12 12.3 0.0 40 4.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EIM83507.1 - 0.15 11.8 0.1 11 5.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EIM83507.1 - 0.31 10.6 3.7 3.2 7.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain Spc7 PF08317.11 EIM83507.1 - 0.67 8.8 8.9 1.2 8.0 8.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 EIM83507.1 - 0.75 9.8 6.4 0.19 11.7 1.1 2.6 3 0 0 3 3 2 0 Laminin Domain II SOAR PF16533.5 EIM83507.1 - 1.1 9.3 5.8 17 5.4 5.7 2.7 1 1 0 1 1 1 0 STIM1 Orai1-activating region PV-1 PF06637.11 EIM83507.1 - 3.7 6.3 9.5 6.5 5.5 9.5 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ATPase PF06745.13 EIM83507.1 - 4 6.7 5.4 7.3 5.9 0.0 3.5 3 1 1 4 4 4 0 KaiC zf-CHCC PF10276.9 EIM83508.1 - 4.1e-17 62.0 1.7 5.8e-17 61.5 1.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.25 EIM83509.1 - 2.1e-53 181.4 0.0 3.9e-52 177.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83509.1 - 4.7e-24 85.1 0.0 1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RR_TM4-6 PF06459.12 EIM83509.1 - 0.15 11.9 3.3 0.24 11.2 3.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pribosyltran_N PF13793.6 EIM83510.1 - 2e-44 150.3 0.2 5.8e-44 148.7 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EIM83510.1 - 9.5e-40 136.6 1.4 5e-33 114.7 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EIM83510.1 - 3.4e-15 55.9 2.0 7.8e-15 54.7 0.4 2.2 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EIM83510.1 - 0.0005 19.6 0.1 0.00086 18.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DCP2 PF05026.13 EIM83511.1 - 6.6e-32 109.7 0.2 9.9e-32 109.1 0.2 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EIM83511.1 - 2e-14 53.8 0.1 6.1e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain INCENP_ARK-bind PF03941.15 EIM83512.1 - 8.7e-20 70.4 0.7 8.7e-20 70.4 0.7 1.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Reticulon PF02453.17 EIM83513.1 - 2.6e-06 27.5 1.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 2 Reticulon DUF3292 PF11696.8 EIM83513.1 - 4.4e-06 25.4 1.2 4.4e-06 25.4 1.2 3.0 3 1 0 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 EIM83513.1 - 0.0095 15.7 0.9 0.07 12.9 0.1 2.2 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Rad21_Rec8_N PF04825.13 EIM83514.1 - 5.8e-24 84.4 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EIM83514.1 - 2.9e-09 36.0 0.0 5.4e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Filo_glycop PF01611.16 EIM83514.1 - 0.19 10.6 0.0 2.1 7.2 0.0 2.0 2 0 0 2 2 2 0 Filovirus glycoprotein NUDIX PF00293.28 EIM83515.1 - 3.7e-23 82.0 0.0 4.7e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF2532 PF10811.8 EIM83515.1 - 0.041 13.9 0.1 0.082 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2532) tRNA-synt_2e PF02091.15 EIM83515.1 - 0.072 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit O-FucT PF10250.9 EIM83516.1 - 2e-09 37.6 0.0 7.3e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase His_Phos_1 PF00300.22 EIM83517.1 - 1.6e-12 47.6 0.0 3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 EIM83517.1 - 1.8 8.4 13.1 2.6 7.9 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MPC PF03650.13 EIM83518.1 - 1.9e-36 124.6 0.1 2.5e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DNA_ligase_A_M PF01068.21 EIM83519.1 - 1.5e-65 220.6 0.3 2.5e-65 219.9 0.3 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIM83519.1 - 2.2e-43 148.6 0.6 4.5e-43 147.6 0.6 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EIM83519.1 - 4.5e-26 91.3 0.0 1.3e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 EIM83519.1 - 0.044 13.8 0.2 7.9 6.6 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Metallophos PF00149.28 EIM83520.1 - 7.5e-38 131.1 0.0 4e-37 128.7 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIM83520.1 - 1.7e-17 63.6 0.1 2.9e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_S17_N PF16205.5 EIM83521.1 - 2.4e-29 101.5 0.5 4.1e-29 100.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EIM83521.1 - 1.3e-27 95.7 1.3 1.8e-27 95.2 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 DUF922 PF06037.11 EIM83521.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) OppC_N PF12911.7 EIM83522.1 - 0.039 13.9 1.6 0.08 12.9 1.6 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Aldo_ket_red PF00248.21 EIM83523.1 - 4e-40 137.8 0.0 1.4e-39 136.0 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM83524.1 - 2.1e-38 132.2 0.0 3.8e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family SGS PF05002.15 EIM83525.1 - 3.8e-33 113.5 2.1 5.8e-33 112.8 2.1 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EIM83525.1 - 1.4e-07 32.4 0.0 2.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 CS domain GST_C_2 PF13410.6 EIM83526.1 - 1e-05 25.4 0.2 2.7e-05 24.1 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM83526.1 - 0.00013 22.2 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM83526.1 - 0.00013 22.3 0.0 0.00044 20.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM83526.1 - 0.00022 21.4 0.2 0.00076 19.7 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM83526.1 - 0.00068 19.8 0.0 0.0029 17.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM83526.1 - 0.024 15.0 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Galactosyl_T PF01762.21 EIM83527.1 - 1.2e-06 28.5 0.0 0.0013 18.6 0.0 2.6 2 1 0 2 2 2 2 Galactosyltransferase Aa_trans PF01490.18 EIM83528.1 - 5.1e-31 107.8 35.2 5.9e-31 107.6 35.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Isochorismatase PF00857.20 EIM83529.1 - 2.6e-08 34.3 0.0 1e-06 29.1 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family DUF2095 PF09868.9 EIM83529.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) TMEM100 PF16311.5 EIM83530.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 EVC2_like PF12297.8 EIM83530.1 - 0.22 10.2 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Ras PF00071.22 EIM83531.1 - 1.1e-53 181.1 0.0 1.4e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM83531.1 - 2.1e-32 111.8 0.0 2.9e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM83531.1 - 1.4e-12 47.4 0.0 1.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIM83531.1 - 3.8e-06 26.6 0.0 0.0003 20.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIM83531.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIM83531.1 - 0.00021 20.7 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIM83531.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EIM83531.1 - 0.0021 17.6 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EIM83531.1 - 0.014 15.7 0.1 0.021 15.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EIM83531.1 - 0.016 15.1 0.0 1.2 9.0 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase DAP3 PF10236.9 EIM83531.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 EIM83531.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EIM83531.1 - 0.026 14.9 0.2 0.059 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EIM83531.1 - 0.03 14.8 0.1 0.091 13.3 0.1 1.9 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 EIM83531.1 - 0.057 13.2 0.0 1.4 8.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 EIM83531.1 - 0.063 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 EIM83531.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.18 EIM83531.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Septin Dehydrin PF00257.19 EIM83531.1 - 0.15 12.6 0.3 0.23 12.0 0.3 1.3 1 0 0 1 1 1 0 Dehydrin AAA_30 PF13604.6 EIM83531.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EIM83531.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain D-ser_dehydrat PF14031.6 EIM83532.1 - 1.9e-24 86.1 0.2 6.5e-24 84.4 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EIM83532.1 - 7.2e-15 55.2 0.2 1.1e-14 54.7 0.2 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ribonuc_L-PSP PF01042.21 EIM83533.1 - 2.5e-34 117.9 0.0 3e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 EIM83534.1 - 3.5e-31 108.4 28.0 1.3e-30 106.5 28.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UCR_TM PF02921.14 EIM83535.1 - 2.4e-12 47.1 0.2 5.2e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EIM83535.1 - 2.8e-11 43.2 0.0 4.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Inv-AAD PF18785.1 EIM83536.1 - 1.1e-25 89.9 0.0 1.8e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EIM83536.1 - 9.7e-14 51.1 0.1 2.6e-13 49.7 0.1 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIM83536.1 - 0.0013 18.5 0.1 0.065 13.0 0.1 2.3 2 0 0 2 2 2 2 MafB19-like deaminase Amidinotransf PF02274.17 EIM83536.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase Nrap_D6 PF17407.2 EIM83537.1 - 0.15 12.3 0.6 0.25 11.5 0.3 1.5 1 1 0 1 1 1 0 Nrap protein domain 6 Polysacc_deac_1 PF01522.21 EIM83538.1 - 5e-29 100.7 0.0 2e-28 98.7 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EIM83538.1 - 0.091 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NAP PF00956.18 EIM83539.1 - 1.7e-25 89.8 7.1 2.4e-23 82.7 3.6 3.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Pyr_redox_2 PF07992.14 EIM83540.1 - 2.8e-21 76.0 0.1 1.2e-14 54.3 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM83540.1 - 1.3e-20 73.9 0.0 9.9e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIM83540.1 - 6.5e-14 51.2 0.1 5.8e-13 48.1 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 EIM83540.1 - 8.1e-09 35.2 0.1 4.3e-05 22.9 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 EIM83540.1 - 8e-08 32.7 0.1 0.0046 17.5 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM83540.1 - 9.1e-08 31.6 0.0 2.9e-06 26.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EIM83540.1 - 2.1e-06 27.1 0.0 0.0066 15.6 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM83540.1 - 3.8e-06 27.0 0.0 4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM83540.1 - 6.7e-05 22.6 0.6 0.038 13.6 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EIM83540.1 - 9.4e-05 22.5 0.0 0.068 13.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EIM83540.1 - 0.00061 19.2 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EIM83540.1 - 0.00072 18.7 0.1 0.007 15.5 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EIM83540.1 - 0.0014 18.6 0.2 1.7 8.6 0.0 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EIM83540.1 - 0.0037 16.0 0.0 0.012 14.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein XdhC_C PF13478.6 EIM83540.1 - 0.0069 16.9 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 EIM83540.1 - 0.011 16.2 0.1 10 6.6 0.0 3.4 3 1 0 3 3 3 0 Putative NAD(P)-binding IlvN PF07991.12 EIM83540.1 - 0.013 15.0 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 EIM83540.1 - 0.039 13.2 0.0 0.49 9.6 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 EIM83540.1 - 0.062 12.6 0.1 0.57 9.5 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EIM83540.1 - 0.088 13.1 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 EIM83540.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dynactin PF12455.8 EIM83541.1 - 6.7e-87 291.3 2.0 6.7e-87 291.3 2.0 3.5 4 1 1 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 EIM83541.1 - 1.1e-20 73.4 1.2 2.6e-20 72.2 1.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain Taq-exonuc PF09281.10 EIM83541.1 - 0.033 14.2 0.3 0.17 11.9 0.3 2.3 1 0 0 1 1 1 0 Taq polymerase, exonuclease F-box-like PF12937.7 EIM83542.1 - 5.2e-11 42.3 0.2 5.2e-11 42.3 0.2 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM83542.1 - 1.3e-06 28.1 1.6 2.3e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EIM83542.1 - 0.23 11.3 1.8 3.7 7.4 0.4 2.6 1 1 1 2 2 2 0 F-box PfkB PF00294.24 EIM83543.1 - 5.8e-66 222.8 0.3 6.6e-66 222.7 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UbiA PF01040.18 EIM83544.1 - 4.8e-26 91.6 7.5 6.3e-26 91.2 7.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ABC_tran PF00005.27 EIM83545.1 - 5e-52 176.1 0.0 1.2e-24 87.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EIM83545.1 - 2.2e-20 73.7 1.4 0.0001 22.2 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EIM83545.1 - 5.9e-19 68.4 46.0 7.7e-11 41.7 24.6 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.6 EIM83545.1 - 3.9e-08 34.0 0.1 0.0067 16.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EIM83545.1 - 0.00033 20.3 1.3 0.24 11.2 0.5 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EIM83545.1 - 0.00059 19.3 3.7 14 5.1 0.0 4.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EIM83545.1 - 0.001 19.0 0.0 0.78 9.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EIM83545.1 - 0.0011 18.8 0.0 0.74 9.5 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_27 PF13514.6 EIM83545.1 - 0.0037 16.9 0.1 0.4 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EIM83545.1 - 0.0037 17.5 1.0 8.9 6.6 0.0 4.6 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF4162 PF13732.6 EIM83545.1 - 0.048 14.4 0.0 14 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_22 PF13401.6 EIM83545.1 - 0.048 13.9 0.2 26 5.1 0.1 3.3 2 2 0 2 2 2 0 AAA domain SRP54 PF00448.22 EIM83545.1 - 0.05 13.2 0.7 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EIM83545.1 - 0.11 12.2 3.3 7.8 6.2 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EIM83545.1 - 0.12 12.8 0.1 29 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EIM83545.1 - 0.13 11.6 0.1 5.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin MukB PF04310.12 EIM83545.1 - 0.2 11.5 0.5 11 5.8 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Chitin_synth_2 PF03142.15 EIM83547.1 - 3.2e-280 930.2 0.0 4.2e-280 929.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EIM83547.1 - 1.9e-11 44.2 0.1 5.4e-11 42.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIM83547.1 - 1.4e-10 41.4 0.0 6.5e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EIM83547.1 - 0.0022 17.5 0.0 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EIM83547.1 - 0.033 14.0 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Inj_translocase PF16928.5 EIM83547.1 - 0.27 10.6 7.5 0.46 9.9 7.5 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome F-box-like PF12937.7 EIM83549.1 - 0.00033 20.5 1.8 0.00033 20.5 1.8 3.4 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EIM83549.1 - 0.097 13.1 4.0 0.37 11.3 0.1 3.9 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EIM83550.1 - 1.5e-05 24.8 2.3 1.5e-05 24.8 2.3 2.8 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EIM83550.1 - 0.01 16.2 2.7 12 6.4 0.0 4.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2791 PF10923.8 EIM83550.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Polysacc_deac_1 PF01522.21 EIM83551.1 - 0.003 17.5 1.4 0.017 15.0 0.7 2.6 2 1 0 2 2 2 1 Polysaccharide deacetylase PAP_assoc PF03828.19 EIM83552.1 - 3e-07 30.6 2.0 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EIM83552.1 - 0.00076 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 EIM83552.1 - 0.0046 17.2 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) NECFESHC PF16621.5 EIM83553.1 - 0.056 13.4 1.2 0.056 13.4 1.2 1.9 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 DUF2835 PF11197.8 EIM83553.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) SelP_N PF04592.14 EIM83553.1 - 0.26 10.6 7.1 0.28 10.5 7.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_L28e PF01778.17 EIM83554.1 - 2.7e-26 92.6 0.0 3.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Phage_GPD PF05954.11 EIM83554.1 - 0.049 12.9 0.1 0.081 12.2 0.1 1.3 1 1 0 1 1 1 0 Phage late control gene D protein (GPD) S4 PF01479.25 EIM83555.1 - 4.1e-11 42.4 1.3 4.1e-11 42.4 1.3 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EIM83555.1 - 4.5e-06 27.5 0.2 9.8e-06 26.4 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 EIM83556.1 - 4.7e-44 148.4 4.1 7.3e-44 147.7 4.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Surface_Ag_2 PF01617.17 EIM83556.1 - 0.013 14.9 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Surface antigen Methyltransf_16 PF10294.9 EIM83558.1 - 1.8e-13 50.6 0.0 3.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EIM83558.1 - 0.0024 18.6 0.0 0.0068 17.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIM83558.1 - 0.0025 17.6 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EIM83558.1 - 0.023 15.4 0.0 0.089 13.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EIM83558.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EIM83558.1 - 0.1 12.4 0.0 0.66 9.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain ImpA_N PF06812.12 EIM83559.1 - 0.043 13.9 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system p450 PF00067.22 EIM83560.1 - 3.5e-71 240.3 0.0 4.4e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 EIM83560.1 - 0.12 12.0 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 TUP1-like enhancer of split PRA-CH PF01502.18 EIM83561.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase Pga1 PF10333.9 EIM83562.1 - 0.06 13.2 0.6 0.16 11.8 0.6 1.7 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator RRM_1 PF00076.22 EIM83563.1 - 2e-25 88.4 0.1 5.3e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM83563.1 - 6.7e-10 38.6 0.0 1.2e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM83563.1 - 7.1e-08 32.2 0.0 4.4e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EIM83563.1 - 0.0016 18.5 0.2 0.022 14.9 0.0 2.4 2 1 0 2 2 2 1 Limkain b1 Nup35_RRM_2 PF14605.6 EIM83563.1 - 0.064 13.3 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SBE2 PF17076.5 EIM83564.1 - 3.5 5.7 6.9 5.9 5.0 6.9 1.3 1 0 0 1 1 1 0 SBE2, cell-wall formation LysM PF01476.20 EIM83566.1 - 9.9e-14 51.1 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF3309 PF11752.8 EIM83566.1 - 0.016 15.2 1.5 0.035 14.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) MARVEL PF01284.23 EIM83567.1 - 1.2e-10 41.6 14.2 1.6e-10 41.2 14.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain NOA36 PF06524.12 EIM83568.1 - 4.2 6.6 11.3 7.6 5.7 11.3 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 EIM83568.1 - 4.2 6.9 6.8 5.3 6.5 6.8 1.1 1 0 0 1 1 1 0 PPP4R2 TPR_14 PF13428.6 EIM83569.1 - 0.38 11.7 1.8 22 6.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RdRP PF05183.12 EIM83571.1 - 1.5e-105 354.1 0.0 2e-105 353.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase 2-Hacid_dh_C PF02826.19 EIM83572.1 - 1.3e-54 184.3 0.0 3.8e-54 182.7 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM83572.1 - 1.7e-09 37.4 0.0 3.6e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIM83572.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EIM83572.1 - 0.21 11.1 0.0 0.46 10.1 0.0 1.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CcmD PF04995.14 EIM83573.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.8 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) RhoGEF PF00621.20 EIM83574.1 - 9.5e-35 120.5 0.0 1.3e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 EIM83574.1 - 4e-18 65.3 8.2 6.4e-18 64.7 8.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EIM83574.1 - 0.1 13.1 0.0 0.53 10.8 0.0 2.2 2 1 1 3 3 3 0 PH domain FYVE_2 PF02318.16 EIM83574.1 - 0.54 10.5 6.2 1 9.6 6.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger CortBP2 PF09727.9 EIM83575.1 - 1 9.3 3.2 0.62 9.9 0.3 2.0 2 0 0 2 2 2 0 Cortactin-binding protein-2 p450 PF00067.22 EIM83576.1 - 2.3e-59 201.4 0.0 4.6e-59 200.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_S12 PF17487.2 EIM83577.1 - 0.096 13.4 4.4 0.35 11.6 4.4 2.0 1 0 0 1 1 1 0 Ribosomal protein S12 DHHC PF01529.20 EIM83578.1 - 2.3e-36 124.9 7.6 2.3e-36 124.9 7.6 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase PEHE PF15275.6 EIM83579.1 - 2e-05 25.2 4.8 2e-05 25.2 4.8 3.6 1 1 2 3 3 3 1 PEHE domain SAS4 PF15460.6 EIM83579.1 - 5.8e-05 23.1 8.1 0.0002 21.4 7.8 2.1 1 1 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Gar1 PF04410.14 EIM83580.1 - 1.9e-32 112.2 0.2 2.7e-32 111.7 0.2 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region EF_TS PF00889.19 EIM83581.1 - 5e-16 58.9 0.0 9.6e-15 54.7 0.0 2.5 2 1 0 2 2 2 1 Elongation factor TS UBA PF00627.31 EIM83581.1 - 0.00049 20.0 0.2 0.00098 19.0 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EIM83581.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Glyco_hydro_15 PF00723.21 EIM83582.1 - 3.3e-93 312.9 0.0 3.8e-93 312.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EIM83582.1 - 1.7e-29 101.6 1.1 4e-29 100.4 1.1 1.7 1 0 0 1 1 1 1 Starch binding domain Glyco_transf_18 PF15024.6 EIM83583.1 - 1.2e-13 50.5 0.0 1.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF668 PF05003.12 EIM83583.1 - 0.092 13.2 0.1 23 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF668) MRJP PF03022.16 EIM83584.1 - 4.4e-27 95.2 0.0 1.4e-26 93.5 0.0 1.6 1 1 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 EIM83584.1 - 0.0093 16.0 0.6 60 3.9 0.0 5.0 5 0 0 5 5 5 0 NHL repeat SGL PF08450.12 EIM83584.1 - 0.03 13.9 0.0 0.33 10.5 0.0 2.6 3 2 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EIM83584.1 - 0.13 12.2 0.2 0.37 10.8 0.2 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Peptidase_M16_C PF05193.21 EIM83585.1 - 2.6e-39 135.2 0.0 5.3e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EIM83585.1 - 3.2e-38 131.0 0.0 5.2e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) BRCA-2_OB1 PF09103.10 EIM83586.1 - 5.8e-36 123.2 0.0 9.2e-36 122.5 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 EIM83586.1 - 6.7e-07 29.1 0.1 1.1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 BRCA2, helical Taxilin PF09728.9 EIM83587.1 - 6.7e-17 61.6 41.1 3.2e-09 36.4 21.9 2.6 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 EIM83587.1 - 4.5e-07 29.6 0.2 0.054 13.3 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like PriA_C PF18074.1 EIM83587.1 - 0.076 13.8 0.6 0.076 13.8 0.6 3.1 2 1 0 2 2 2 0 Primosomal protein N C-terminal domain Peptidase_S64 PF08192.11 EIM83587.1 - 0.15 10.5 5.0 0.23 9.9 5.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Bacillus_HBL PF05791.11 EIM83587.1 - 0.23 11.3 7.0 0.45 10.3 7.0 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Thy1 PF02511.15 EIM83587.1 - 0.45 10.3 5.7 1.1 9.0 5.7 1.6 1 0 0 1 1 1 0 Thymidylate synthase complementing protein DUF2333 PF10095.9 EIM83587.1 - 0.56 9.2 6.2 0.95 8.4 6.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) DUF2935 PF11155.8 EIM83587.1 - 0.96 9.8 7.8 0.3 11.4 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Leu_zip PF15294.6 EIM83587.1 - 1.9 7.9 26.5 0.21 11.0 15.7 2.2 2 0 0 2 2 2 0 Leucine zipper IF-2B PF01008.17 EIM83587.1 - 4.8 6.3 8.3 4 6.5 6.5 1.7 1 1 1 2 2 2 0 Initiation factor 2 subunit family FapA PF03961.13 EIM83587.1 - 7.1 5.1 22.7 0.56 8.8 12.7 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 EIM83587.1 - 8.8 6.4 10.6 2.2 8.4 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CBP_BcsR PF10945.8 EIM83588.1 - 0.11 12.0 0.7 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR HNH_repeat PF18780.1 EIM83589.1 - 1.6 8.6 0.0 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Homing endonuclease repeat UDPGP PF01704.18 EIM83590.1 - 2e-47 161.8 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EIM83590.1 - 0.0061 16.9 0.1 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Cellulase PF00150.18 EIM83591.1 - 1.2e-12 47.9 0.3 1.2e-12 47.9 0.3 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Lum_binding PF00677.17 EIM83593.1 - 5.4e-44 148.1 0.0 1.2e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Zn_clus PF00172.18 EIM83594.1 - 1.9e-08 34.3 5.5 2.8e-08 33.7 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NST1 PF13945.6 EIM83594.1 - 0.2 11.8 6.3 0.32 11.1 6.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Agouti PF05039.12 EIM83594.1 - 0.49 11.1 8.3 0.82 10.4 8.3 1.3 1 0 0 1 1 1 0 Agouti protein DUF2457 PF10446.9 EIM83594.1 - 1.4 8.0 7.9 1.5 7.9 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macoilin PF09726.9 EIM83594.1 - 6.2 5.3 6.9 7.4 5.0 6.9 1.0 1 0 0 1 1 1 0 Macoilin family HLH PF00010.26 EIM83595.1 - 4.8e-06 26.4 0.0 8.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.13 EIM83595.1 - 3.1 7.0 6.0 3.8 6.7 6.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) E1-E2_ATPase PF00122.20 EIM83596.1 - 8.6e-37 126.4 3.5 1.1e-35 122.8 0.1 3.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EIM83596.1 - 6.7e-19 69.0 0.1 1.5e-18 67.9 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIM83596.1 - 3.6e-06 26.6 0.0 1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIM83596.1 - 0.0014 18.4 0.2 0.0042 16.9 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_S24 PF00717.23 EIM83596.1 - 0.11 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Peptidase S24-like zf-MYND PF01753.18 EIM83597.1 - 2.4e-11 43.5 14.6 4.3e-11 42.7 14.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM83597.1 - 4.8 7.6 15.5 0.17 12.2 8.9 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding ADH_zinc_N PF00107.26 EIM83601.1 - 2.2e-10 40.6 0.0 5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM83601.1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM83601.1 - 0.0014 19.7 0.0 0.0024 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM83601.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Peptidase_S10 PF00450.22 EIM83602.1 - 2.8e-112 376.2 0.0 3.5e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EIM83602.1 - 0.00035 21.2 0.1 0.0042 17.7 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.32 EIM83603.1 - 1.9e-35 120.3 42.8 7.2e-07 29.8 0.1 12.1 13 0 0 13 13 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM83603.1 - 2e-28 98.5 0.6 0.00041 20.6 0.0 10.3 4 4 7 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EIM83603.1 - 9.7e-14 51.5 0.8 1.9e-05 24.3 0.0 5.1 1 1 3 4 4 4 3 PQQ-like domain PD40 PF07676.12 EIM83603.1 - 3.5e-10 39.6 2.3 0.92 9.5 0.0 8.2 8 1 1 9 9 9 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EIM83603.1 - 9.4e-10 38.0 1.4 0.48 9.3 0.0 6.8 5 2 3 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 EIM83603.1 - 3.2e-09 36.9 0.5 2.9e-08 33.8 0.1 2.2 2 0 0 2 2 2 1 NACHT domain eIF2A PF08662.11 EIM83603.1 - 7.3e-07 29.2 0.0 0.079 12.8 0.0 4.5 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 EIM83603.1 - 1.7e-06 28.5 0.0 5e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Gmad1 PF10647.9 EIM83603.1 - 4.4e-06 26.6 0.1 0.4 10.4 0.0 4.5 3 1 1 4 4 4 2 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.6 EIM83603.1 - 7.8e-05 22.1 1.4 1.3 8.3 0.0 5.2 5 0 0 5 5 5 1 Neuroblastoma-amplified sequence, N terminal NB-ARC PF00931.22 EIM83603.1 - 0.00029 20.1 0.0 0.00076 18.7 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 EIM83603.1 - 0.0003 21.1 0.0 0.00075 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EIM83603.1 - 0.00038 20.9 0.0 0.0013 19.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Nup160 PF11715.8 EIM83603.1 - 0.0024 16.6 0.7 2.8 6.5 0.1 4.1 5 0 0 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM83603.1 - 0.0034 16.8 0.2 0.42 9.9 0.0 2.8 2 1 0 2 2 2 1 WD40-like domain APS_kinase PF01583.20 EIM83603.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 EIM83603.1 - 0.035 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MeaB PF03308.16 EIM83603.1 - 0.038 13.0 0.0 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EIM83603.1 - 0.039 13.2 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EIM83603.1 - 0.047 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EIM83603.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.15 EIM83603.1 - 0.069 13.1 0.1 0.33 10.8 0.0 2.1 3 0 0 3 3 2 0 NTPase ABC_tran PF00005.27 EIM83603.1 - 0.19 12.2 0.0 0.51 10.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EIM83603.1 - 0.25 11.1 0.3 1.5 8.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF1513 PF07433.11 EIM83603.1 - 0.27 10.3 0.6 4.7 6.2 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) PUF PF00806.19 EIM83604.1 - 2.6e-28 96.1 0.1 1.8e-07 30.5 0.0 6.6 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat PRIMA1 PF16101.5 EIM83604.1 - 0.37 10.8 5.5 1.5 8.8 5.5 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pyridox_oxase_2 PF12766.7 EIM83605.1 - 7e-22 77.9 0.0 1.5e-21 76.8 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase tRNA-synt_His PF13393.6 EIM83606.1 - 2.3e-38 132.2 0.1 2e-33 116.0 0.0 2.6 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EIM83606.1 - 2e-11 43.9 0.2 4e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EIM83606.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Ribosomal_60s PF00428.19 EIM83606.1 - 4.9 7.8 10.3 0.93 10.1 5.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C48 PF02902.19 EIM83607.1 - 2.1e-21 76.8 0.0 8e-21 74.9 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MT PF12777.7 EIM83607.1 - 0.025 13.6 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor CDP-OH_P_transf PF01066.21 EIM83608.1 - 2.4e-18 66.6 0.0 2.4e-18 66.6 0.0 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2235 PF09994.9 EIM83609.1 - 1.1e-89 300.7 0.1 1.3e-89 300.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-C2H2 PF00096.26 EIM83611.1 - 0.0047 17.3 3.0 0.074 13.5 1.5 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type DUF3268 PF11672.8 EIM83611.1 - 0.039 14.3 0.4 0.067 13.5 0.4 1.3 1 0 0 1 1 1 0 zinc-finger-containing domain zf-H2C2_5 PF13909.6 EIM83611.1 - 0.085 12.6 1.2 0.3 10.9 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-MYST PF17772.1 EIM83611.1 - 0.12 12.0 0.6 5.7 6.6 0.4 2.7 3 0 0 3 3 3 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 EIM83611.1 - 0.12 12.9 5.9 0.2 12.1 1.0 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM83611.1 - 0.47 11.4 13.0 0.61 11.1 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1677 PF07911.13 EIM83611.1 - 1.6 9.2 3.8 6.7 7.2 3.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1677) DAO PF01266.24 EIM83613.1 - 3.9e-35 122.1 0.0 5.2e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM83613.1 - 0.0022 18.2 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM83613.1 - 0.0034 16.7 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EIM83613.1 - 0.0079 16.2 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Bot1p PF12298.8 EIM83614.1 - 2.5e-23 83.1 1.4 5.3e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Methyltransf_16 PF10294.9 EIM83615.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase ComJ PF11033.8 EIM83615.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Competence protein J (ComJ) DUF3352 PF11832.8 EIM83615.1 - 0.058 12.0 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) MTS PF05175.14 EIM83615.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EIM83615.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EIM83615.1 - 0.21 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EIM83616.1 - 6.9e-13 49.1 0.0 1.9e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM83616.1 - 8.2e-10 39.2 0.0 2.5e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM83616.1 - 4e-08 33.3 0.0 9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM83616.1 - 3e-05 24.7 0.4 0.0033 18.1 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM83616.1 - 0.00033 20.1 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EIM83616.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EIM83616.1 - 0.0021 17.6 0.1 0.022 14.2 0.0 2.5 2 0 0 2 2 2 1 Putative methyltransferase SF3b10 PF07189.11 EIM83617.1 - 4e-34 116.6 0.0 4.8e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TetR_C_27 PF17935.1 EIM83617.1 - 0.082 13.0 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF727 PF05303.12 EIM83618.1 - 0.0001 22.3 0.1 0.00024 21.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Sas10_Utp3 PF04000.15 EIM83619.1 - 2e-16 60.4 0.0 4.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF4604 PF15377.6 EIM83619.1 - 3.3 8.1 14.5 6.8 7.1 14.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) F-box-like PF12937.7 EIM83620.1 - 1.3e-05 24.9 0.0 3.5e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EIM83620.1 - 0.00013 21.8 11.8 3.8 7.8 0.0 6.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 EIM83620.1 - 0.00039 20.7 4.1 0.6 10.6 0.0 5.4 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIM83620.1 - 0.44 11.3 13.0 32 5.6 0.2 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat YABBY PF04690.13 EIM83621.1 - 4.9e-09 37.0 0.0 5.2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 EIM83621.1 - 0.00015 22.3 0.2 0.00015 22.3 0.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 EIM83621.1 - 0.00018 22.0 0.3 0.00022 21.8 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EIM83621.1 - 0.019 15.3 1.1 0.023 15.1 1.1 1.1 1 0 0 1 1 1 0 HMG (high mobility group) box Sec1 PF00995.23 EIM83622.1 - 3.7e-109 366.6 0.0 6.7e-109 365.7 0.0 1.4 1 1 0 1 1 1 1 Sec1 family SKA2 PF16740.5 EIM83622.1 - 0.067 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF3446 PF11928.8 EIM83622.1 - 0.56 10.6 3.9 0.4 11.0 0.7 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain cNMP_binding PF00027.29 EIM83623.1 - 4.8e-29 100.3 0.0 6.4e-16 58.2 0.0 5.3 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EIM83623.1 - 2.5e-17 63.7 7.4 3.4e-12 47.0 2.6 3.5 3 0 0 3 3 3 2 Patatin-like phospholipase Chitin_synth_1 PF01644.17 EIM83624.1 - 2.1e-70 235.9 0.2 3e-70 235.4 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIM83624.1 - 2.6e-26 91.4 0.1 6.5e-26 90.1 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIM83624.1 - 4.8e-24 84.9 0.1 8.2e-19 67.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIM83624.1 - 2.1e-06 27.8 0.1 2.1e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Pkinase PF00069.25 EIM83626.1 - 4e-26 92.0 0.0 5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83626.1 - 1.2e-13 51.0 0.0 1.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM83626.1 - 1.3e-09 37.4 0.1 1.7e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM83626.1 - 0.001 19.1 0.0 0.0064 16.4 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EIM83626.1 - 0.021 13.8 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3793 PF12672.7 EIM83626.1 - 0.041 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Kdo PF06293.14 EIM83626.1 - 0.061 12.7 0.4 0.097 12.0 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF917 PF06032.12 EIM83628.1 - 5.2e-19 68.3 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Pneumovirus_M2 PF06436.11 EIM83628.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Aldedh PF00171.22 EIM83629.1 - 2.3e-39 135.2 0.0 1.5e-20 73.1 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF3915 PF13054.6 EIM83631.1 - 0.048 13.7 1.5 0.087 12.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3385 PF11865.8 EIM83632.1 - 0.016 15.1 0.1 0.75 9.7 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) F-box-like PF12937.7 EIM83633.1 - 9.8e-10 38.2 2.5 7.7e-09 35.3 1.5 3.0 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EIM83633.1 - 0.01 15.7 0.4 6.9 6.7 0.0 3.3 2 0 0 2 2 2 0 F-box domain LOR PF04525.12 EIM83634.1 - 0.042 13.4 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 LURP-one-related SNF2_N PF00176.23 EIM83636.1 - 1e-20 73.8 0.9 1.6e-18 66.6 0.9 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM83636.1 - 0.00012 22.4 0.0 0.00047 20.5 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Ribonuclease_3 PF00636.26 EIM83639.1 - 0.01 16.4 0.0 0.013 16.1 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease III domain SMN PF06003.12 EIM83639.1 - 0.22 10.8 5.4 0.27 10.4 5.4 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Macoilin PF09726.9 EIM83642.1 - 3.6 6.0 5.6 5.5 5.4 5.6 1.2 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 EIM83643.1 - 0.012 15.1 7.5 0.017 14.6 7.5 1.2 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 EIM83643.1 - 0.013 15.0 1.0 0.023 14.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 EIM83643.1 - 0.74 9.4 9.6 1 8.9 9.6 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 EIM83643.1 - 0.9 7.7 13.7 1.2 7.3 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 EIM83643.1 - 1.5 7.9 13.6 2.4 7.2 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF917 PF06032.12 EIM83645.1 - 5.3e-16 58.4 0.0 2e-15 56.5 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF917) AAA PF00004.29 EIM83650.1 - 6.6e-16 58.9 0.0 1.4e-14 54.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM83650.1 - 0.00012 22.5 0.0 0.00019 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM83650.1 - 0.00074 19.8 0.0 0.0027 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EIM83650.1 - 0.0021 18.2 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM83650.1 - 0.0024 18.4 0.0 0.0066 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EIM83650.1 - 0.0027 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EIM83650.1 - 0.0057 16.5 0.0 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM83650.1 - 0.023 14.7 0.0 0.067 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EIM83650.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EIM83650.1 - 0.045 13.5 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 EIM83650.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EIM83650.1 - 0.089 13.0 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EIM83650.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 EIM83650.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EIM83650.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 EIM83650.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIM83650.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EIM83650.1 - 0.17 12.4 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EIM83650.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EIM83650.1 - 0.17 11.8 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EIM83650.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 EIM83651.1 - 0.075 13.4 12.5 0.12 12.7 12.5 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 EIM83651.1 - 0.094 13.0 5.3 0.098 13.0 4.1 1.7 1 1 0 1 1 1 0 RING-like domain 2OG-FeII_Oxy_3 PF13640.6 EIM83652.1 - 0.06 14.2 0.0 0.094 13.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_6 PF13174.6 EIM83652.1 - 0.1 13.3 0.1 17 6.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.23 EIM83656.1 - 1.8e-12 47.3 1.8 3.2e-12 46.6 1.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM83656.1 - 8.4e-07 29.4 5.8 2.3e-06 28.0 5.8 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIM83656.1 - 0.03 14.5 0.1 0.043 14.0 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EIM83656.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated G-alpha PF00503.20 EIM83658.1 - 5.3e-33 114.6 0.7 8.5e-33 114.0 0.7 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM83658.1 - 5.8e-06 25.9 2.6 1.2e-05 24.9 0.4 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family BRE1 PF08647.11 EIM83658.1 - 5.7 7.1 7.3 1.8 8.7 2.7 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Glyco_trans_2_3 PF13632.6 EIM83661.1 - 3.1e-05 24.0 0.1 3.1e-05 24.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Fez1 PF06818.15 EIM83662.1 - 5.4 7.4 9.9 1.3 9.5 4.8 2.3 3 1 0 3 3 3 0 Fez1 zf-RVT PF13966.6 EIM83670.1 - 4e-07 30.7 1.5 8.5e-07 29.6 1.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 EIM83670.1 - 0.00018 21.7 0.0 0.0004 20.6 0.0 1.6 1 0 0 1 1 1 1 RNase H HTH_33 PF13592.6 EIM83670.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix F-box-like PF12937.7 EIM83672.1 - 0.0001 22.1 0.5 0.00042 20.1 0.5 2.2 1 0 0 1 1 1 1 F-box-like Rad60-SLD PF11976.8 EIM83672.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Membralin PF09746.9 EIM83672.1 - 0.24 10.4 1.9 3.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Tumour-associated protein TRAP-gamma PF07074.12 EIM83673.1 - 0.38 10.3 0.8 0.54 9.8 0.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Gti1_Pac2 PF09729.9 EIM83674.1 - 9.8e-42 143.1 0.6 3.4e-35 121.8 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Mannitol_dh_C PF08125.13 EIM83675.1 - 1.3e-07 31.4 0.0 1.4e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Clr2_transil PF16761.5 EIM83676.1 - 6e-11 43.0 0.9 1.9e-10 41.4 0.9 1.9 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EIM83676.1 - 6.1e-08 33.6 0.0 1.6e-07 32.2 0.0 1.8 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 CBM_1 PF00734.18 EIM83677.1 - 1.6e-11 43.9 12.7 4e-11 42.7 12.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Sortilin-Vps10 PF15902.5 EIM83677.1 - 3.1e-11 42.8 5.1 0.0042 15.9 0.0 5.9 5 2 1 6 6 6 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 EIM83677.1 - 0.00042 19.9 25.0 4.2 7.8 0.1 8.7 9 0 0 9 9 9 4 BNR/Asp-box repeat BNR_6 PF15899.5 EIM83677.1 - 0.0021 18.0 2.8 12 6.3 0.1 5.1 4 0 0 4 4 4 2 BNR-Asp box repeat SIX1_SD PF16878.5 EIM83678.1 - 0.04 14.4 0.0 0.077 13.5 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain zf-C6H2 PF15801.5 EIM83679.1 - 0.039 14.3 1.8 0.081 13.3 1.8 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ORC6 PF05460.13 EIM83680.1 - 0.14 11.4 3.2 0.16 11.2 3.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Retrotran_gag_2 PF14223.6 EIM83681.1 - 1e-20 73.8 0.6 1.4e-20 73.4 0.6 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EIM83681.1 - 0.0028 17.7 0.2 0.0049 16.9 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_3 PF14244.6 EIM83681.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3544 PF12064.8 EIM83681.1 - 3.4 7.9 11.1 3.9 7.7 9.2 1.9 2 0 0 2 2 2 0 Protein kinase C-binding protein 1 DDE_3 PF13358.6 EIM83683.1 - 3.4e-09 36.6 0.0 4.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EIM83683.1 - 2.2e-06 27.3 0.2 2.2e-06 27.3 0.2 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EIM83683.1 - 0.00048 20.1 0.0 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EIM83683.1 - 0.00097 19.7 0.8 0.021 15.4 0.7 2.6 2 1 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 EIM83683.1 - 0.0044 17.1 0.0 0.79 9.8 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 EIM83683.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 EIM83683.1 - 0.047 13.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 EIM83683.1 - 0.082 13.1 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 EIM83683.1 - 0.088 12.6 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 MerR family regulatory protein TLP1_add_C PF18313.1 EIM83683.1 - 0.1 12.5 0.2 0.27 11.2 0.1 1.7 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain YfdX PF10938.8 EIM83685.1 - 0.2 11.6 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 YfdX protein Retrotran_gag_2 PF14223.6 EIM83686.1 - 2.1e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EIM83686.1 - 0.033 14.3 4.4 0.086 13.0 4.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-RING_5 PF14634.6 EIM83687.1 - 2.2e-09 37.1 5.5 3.5e-09 36.5 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM83687.1 - 1.6e-08 34.3 5.5 3e-08 33.4 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EIM83687.1 - 8.6e-08 32.1 8.5 3.4e-07 30.2 8.6 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM83687.1 - 4.3e-07 29.7 4.3 7.7e-07 28.9 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM83687.1 - 5.9e-07 29.7 7.6 9.9e-07 29.0 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM83687.1 - 8.1e-05 22.4 11.3 0.00022 21.0 11.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM83687.1 - 9.6e-05 22.2 7.6 0.00017 21.4 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM83687.1 - 0.0059 16.7 6.7 0.018 15.2 6.7 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EIM83687.1 - 0.009 15.9 0.4 0.016 15.0 0.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EIM83687.1 - 0.019 14.7 5.9 0.037 13.8 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sec34 PF04136.15 EIM83687.1 - 0.034 14.0 0.4 0.057 13.3 0.4 1.2 1 0 0 1 1 1 0 Sec34-like family zf-RING_11 PF17123.5 EIM83687.1 - 0.14 11.9 0.8 0.33 10.7 0.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EIM83687.1 - 0.16 12.3 6.2 0.35 11.2 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C2HC_2 PF13913.6 EIM83687.1 - 0.22 11.5 2.4 0.42 10.6 1.6 1.9 2 0 0 2 2 1 0 zinc-finger of a C2HC-type DUF1272 PF06906.11 EIM83687.1 - 0.54 10.4 4.3 1.2 9.3 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rtf2 PF04641.12 EIM83687.1 - 0.95 8.8 7.4 0.09 12.1 1.1 2.3 2 1 0 2 2 2 0 Rtf2 RING-finger U1snRNP70_N PF12220.8 EIM83687.1 - 5.7 7.6 10.9 2.9 8.6 3.3 3.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal p450 PF00067.22 EIM83691.1 - 2.2e-43 148.7 0.0 2.9e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Suc_Fer-like PF06999.12 EIM83692.1 - 5.6e-22 78.6 0.0 6.7e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like TIM PF00121.18 EIM83693.1 - 1.3e-90 303.0 0.0 1.5e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Pkinase PF00069.25 EIM83694.1 - 3.8e-07 29.8 0.0 6.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83694.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EIM83694.1 - 0.0012 18.2 0.4 0.004 16.5 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM83694.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mo25 PF08569.11 EIM83695.1 - 3.2e-128 427.7 3.2 3.6e-128 427.5 3.2 1.0 1 0 0 1 1 1 1 Mo25-like Aldo_ket_red PF00248.21 EIM83696.1 - 2.2e-59 201.1 0.0 2.6e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM83697.1 - 2.6e-55 187.7 0.1 3e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aurora-A_bind PF09041.10 EIM83697.1 - 0.12 12.4 0.1 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Aurora-A binding DUF1744 PF08490.12 EIM83698.1 - 6.5e-132 439.9 0.0 1.2e-131 439.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EIM83698.1 - 9.7e-70 235.3 0.0 1.5e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EIM83698.1 - 1.5e-10 40.5 0.8 3e-05 22.9 0.0 3.7 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EIM83698.1 - 1.5e-08 34.6 0.4 5.7e-08 32.7 0.4 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EIM83698.1 - 0.00046 20.2 0.0 0.002 18.2 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF3716 PF12511.8 EIM83698.1 - 0.15 12.1 2.1 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) zf-C4pol PF14260.6 EIM83698.1 - 0.44 11.1 5.5 1.7 9.2 5.5 2.1 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Pro-kuma_activ PF09286.11 EIM83699.1 - 9.9e-33 113.4 0.0 2.1e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM83699.1 - 1.2e-05 24.7 0.2 2.1e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Subtilase family p450 PF00067.22 EIM83701.1 - 9.3e-59 199.4 0.0 1.4e-58 198.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM83702.1 - 1.4e-27 96.6 0.0 2.2e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EIM83703.1 - 4.4e-64 216.9 0.0 5.9e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GLE1 PF07817.13 EIM83704.1 - 1.3e-43 149.0 0.1 3.6e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 GLE1-like protein RNA_pol_Rpb5_C PF01191.19 EIM83705.1 - 8.1e-31 105.7 0.3 1.9e-30 104.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EIM83705.1 - 3.7e-27 94.7 0.1 8.1e-27 93.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EIM83705.1 - 0.0037 17.3 0.0 0.0067 16.4 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease F-box-like PF12937.7 EIM83706.1 - 2.2e-08 33.8 1.4 2.2e-08 33.8 1.4 2.8 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 EIM83706.1 - 0.1 12.5 0.4 1.3 9.0 0.1 3.2 2 1 0 2 2 2 0 F-box domain Transp_cyt_pur PF02133.15 EIM83707.1 - 6.6e-88 295.4 29.7 9e-82 275.2 23.4 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 EIM83708.1 - 4.3e-121 404.0 1.3 7.7e-121 403.2 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EIM83708.1 - 1.1e-26 93.6 0.1 6.7e-26 91.1 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EIM83708.1 - 2.2e-18 66.5 4.0 9.8e-17 61.1 0.1 3.4 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EIM83708.1 - 0.01 15.4 4.2 0.048 13.1 0.1 3.1 4 0 0 4 4 4 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 EIM83708.1 - 0.025 13.8 0.3 1.2 8.3 0.1 2.4 2 0 0 2 2 2 0 StbA protein DAHP_snth_FXD PF18152.1 EIM83708.1 - 0.073 12.9 0.1 0.66 9.8 0.1 2.7 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain SWI-SNF_Ssr4 PF08549.10 EIM83708.1 - 0.18 10.4 0.4 0.28 9.8 0.4 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3439 PF11921.8 EIM83708.1 - 9.8 6.2 10.3 27 4.7 9.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Tmemb_18A PF09771.9 EIM83710.1 - 0.012 16.0 0.0 2 8.8 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 188 Beta-lactamase PF00144.24 EIM83711.1 - 6.6e-36 124.2 0.0 1.2e-35 123.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EIM83711.1 - 0.023 15.2 0.1 0.069 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) ADH_zinc_N PF00107.26 EIM83712.1 - 1.6e-14 54.0 0.4 2.7e-14 53.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM83712.1 - 1.4e-07 32.6 0.0 2.4e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM83712.1 - 3.2e-05 23.8 0.1 9e-05 22.3 0.1 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM83713.1 - 8.3e-14 51.7 0.1 1.3e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM83713.1 - 1.3e-07 32.7 0.0 2.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM83713.1 - 8.2e-06 25.7 0.1 2.5e-05 24.1 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-RING_5 PF14634.6 EIM83714.1 - 9.7e-07 28.7 9.0 1.7e-06 27.9 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EIM83714.1 - 1e-06 29.0 10.7 1.8e-06 28.1 10.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM83714.1 - 2.2e-06 27.4 6.4 5.9e-06 26.0 6.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM83714.1 - 1.3e-05 25.1 10.1 0.00031 20.7 6.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM83714.1 - 2.6e-05 24.0 11.0 5e-05 23.1 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM83714.1 - 3.4e-05 23.9 9.3 8e-05 22.7 9.4 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EIM83714.1 - 0.00043 20.0 10.3 0.00068 19.4 10.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EIM83714.1 - 0.0025 17.6 10.8 0.012 15.5 11.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM83714.1 - 0.0037 17.1 14.5 0.028 14.3 14.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 EIM83714.1 - 0.0099 16.0 7.8 0.0099 16.0 7.8 2.0 2 1 0 2 2 2 1 FYVE zinc finger Pellino PF04710.14 EIM83714.1 - 0.12 11.0 1.1 0.16 10.6 1.1 1.1 1 0 0 1 1 1 0 Pellino zf-rbx1 PF12678.7 EIM83714.1 - 0.41 11.0 8.7 0.85 10.0 8.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rtf2 PF04641.12 EIM83714.1 - 0.52 9.6 3.8 0.17 11.3 0.9 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_11 PF17123.5 EIM83714.1 - 2.2 8.1 11.6 0.62 9.9 7.7 2.2 2 0 0 2 2 2 0 RING-like zinc finger Ribosomal_L24e PF01246.20 EIM83715.1 - 2.4e-29 101.4 4.2 3.6e-29 100.8 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L24e MFS_1 PF07690.16 EIM83716.1 - 1.8e-29 102.8 27.0 1.8e-29 102.8 27.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 EIM83716.1 - 0.00034 20.3 0.3 0.11 12.2 0.0 3.4 3 0 0 3 3 3 1 Bacteriophage holin family, superfamily II-like MFS_1_like PF12832.7 EIM83716.1 - 0.00075 18.5 6.2 0.0011 17.9 0.3 2.7 1 1 0 2 2 2 1 MFS_1 like family Pkinase PF00069.25 EIM83718.1 - 3.3e-74 249.6 0.0 5.3e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83718.1 - 1.9e-40 138.8 0.0 3e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM83718.1 - 6e-12 45.5 0.0 9.6e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YhcG_C PF06250.11 EIM83718.1 - 0.028 14.3 1.9 0.78 9.6 0.2 2.2 1 1 2 3 3 3 0 YhcG PDDEXK nuclease domain Kdo PF06293.14 EIM83718.1 - 0.044 13.1 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIM83718.1 - 0.18 10.7 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF3328 PF11807.8 EIM83719.1 - 2.1e-19 70.2 0.2 3.8e-19 69.3 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.9 EIM83720.1 - 0.00013 22.4 3.4 0.00024 21.5 3.4 1.5 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF1349 PF07081.11 EIM83721.1 - 1.3e-35 122.8 0.2 1.5e-35 122.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GFA PF04828.14 EIM83722.1 - 6.4e-07 29.6 24.0 0.11 12.9 0.3 5.4 4 1 1 5 5 5 4 Glutathione-dependent formaldehyde-activating enzyme Synaptobrevin PF00957.21 EIM83723.1 - 2e-27 94.8 5.8 2.5e-27 94.5 5.8 1.1 1 0 0 1 1 1 1 Synaptobrevin TMEM154 PF15102.6 EIM83723.1 - 0.026 14.4 0.4 0.036 14.0 0.4 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 EIM83723.1 - 0.043 12.6 0.2 0.042 12.6 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Baculo_F PF12259.8 EIM83723.1 - 0.051 12.1 1.1 0.057 11.9 1.1 1.0 1 0 0 1 1 1 0 Baculovirus F protein Pex19 PF04614.12 EIM83723.1 - 0.099 12.4 0.4 0.11 12.2 0.4 1.1 1 0 0 1 1 1 0 Pex19 protein family EMP24_GP25L PF01105.24 EIM83723.1 - 0.1 12.6 0.4 0.14 12.1 0.4 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ABC_tran_CTD PF16326.5 EIM83723.1 - 0.15 12.3 0.2 0.22 11.8 0.2 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain GP41 PF00517.17 EIM83723.1 - 1.3 8.8 10.6 3.2 7.6 0.3 2.0 1 1 1 2 2 2 0 Retroviral envelope protein Synaptobrevin PF00957.21 EIM83727.1 - 1.6e-30 104.7 0.5 2.4e-30 104.2 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EIM83727.1 - 1.6e-20 72.9 0.0 2.6e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ribosomal_S11 PF00411.19 EIM83728.1 - 4.7e-47 158.9 1.4 5.9e-47 158.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EIM83728.1 - 0.076 13.3 0.1 0.15 12.3 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) HTH_31 PF13560.6 EIM83730.1 - 1.1e-06 28.9 0.0 1.2e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EIM83730.1 - 4.3e-05 23.5 0.0 4.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EIM83730.1 - 7.1e-05 22.7 0.0 8.9e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EIM83730.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 EIM83730.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DUF2316 PF10078.9 EIM83730.1 - 0.04 14.2 0.0 0.16 12.2 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) EI24 PF07264.11 EIM83731.1 - 1.1 9.5 12.2 3.2 8.0 6.9 2.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) UNC-50 PF05216.13 EIM83731.1 - 8.6 5.9 15.7 1.4 8.4 9.8 2.0 1 1 1 2 2 2 0 UNC-50 family Hydantoinase_B PF02538.14 EIM83732.1 - 1.2e-203 677.2 0.0 1.4e-203 677.0 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase PHD PF00628.29 EIM83733.1 - 1.4e-06 28.1 3.2 1.4e-06 28.1 3.2 3.8 5 0 0 5 5 5 1 PHD-finger Cript PF10235.9 EIM83733.1 - 0.9 10.1 4.4 0.94 10.1 2.1 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Aldedh PF00171.22 EIM83734.1 - 2.3e-83 280.3 0.0 2.7e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACT_7 PF13840.6 EIM83734.1 - 0.038 13.8 0.0 0.77 9.6 0.0 2.6 2 0 0 2 2 2 0 ACT domain IDH PF03971.14 EIM83734.1 - 0.2 10.0 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase MAP65_ASE1 PF03999.12 EIM83736.1 - 1.1e-65 222.6 0.9 2.5e-62 211.5 0.2 2.2 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) FH2 PF02181.23 EIM83736.1 - 0.16 11.1 3.0 0.58 9.2 3.0 1.9 1 1 0 1 1 1 0 Formin Homology 2 Domain Exonuc_VII_L PF02601.15 EIM83736.1 - 2.5 7.6 3.9 7.6 6.0 0.9 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit FNIP_C PF14638.6 EIM83737.1 - 0.05 13.2 0.1 0.05 13.2 0.1 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus EI24 PF07264.11 EIM83738.1 - 0.44 10.8 4.9 0.51 10.5 4.9 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Lactonase PF10282.9 EIM83739.1 - 2.5e-36 125.6 0.0 3.1e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Acetyltransf_1 PF00583.25 EIM83740.1 - 1.2e-11 44.8 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM83740.1 - 6.2e-09 36.2 0.1 8.9e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM83740.1 - 1.3e-07 31.6 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM83740.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MF_alpha_N PF05436.11 EIM83744.1 - 0.15 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Proteasome PF00227.26 EIM83745.1 - 6.3e-36 123.6 0.0 8.2e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.32 EIM83746.1 - 5.2e-43 141.4 12.2 4.3e-10 38.4 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EIM83746.1 - 6.6e-37 125.8 2.8 4.4e-19 68.7 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EIM83746.1 - 1.2e-32 111.5 10.9 2.2e-13 49.8 0.6 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EIM83746.1 - 1e-31 106.1 6.8 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EIM83746.1 - 1.1e-27 94.2 8.5 1.6e-06 27.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EIM83746.1 - 2.4e-16 59.8 0.3 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EIM83746.1 - 3.2e-10 39.9 0.7 7.6e-05 22.6 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EIM83746.1 - 1.5e-08 35.0 0.0 0.0015 18.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EIM83746.1 - 1.2e-06 28.5 0.1 0.042 13.9 0.0 3.3 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EIM83746.1 - 2.8e-05 24.9 0.0 0.019 15.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 EIM83746.1 - 7.6e-05 22.7 1.0 0.00035 20.6 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 EIM83746.1 - 0.00025 21.2 5.8 0.026 14.7 0.9 3.0 1 1 3 4 4 4 2 Dockerin type I domain DUF1103 PF06513.11 EIM83746.1 - 0.00039 20.1 1.2 0.00045 19.9 1.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 EIM83746.1 - 0.00061 19.8 0.5 0.4 10.6 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 EIM83746.1 - 0.0019 18.9 0.2 1.5 9.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 EIM83746.1 - 0.0029 18.1 0.0 1.1 9.8 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 EIM83746.1 - 0.0029 17.8 0.1 0.74 10.1 0.0 3.0 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein TerB PF05099.13 EIM83746.1 - 0.0029 17.5 0.2 0.48 10.4 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 EIM83746.1 - 0.0096 16.2 0.5 5.9 7.2 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 EF-hand_14 PF17959.1 EIM83746.1 - 0.012 16.0 0.1 5.4 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain MotA_activ PF09114.10 EIM83746.1 - 0.02 15.0 0.4 0.3 11.2 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF5580 PF17743.1 EIM83746.1 - 0.02 13.5 0.0 0.02 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EIM83746.1 - 0.023 14.5 0.5 1.5 8.7 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 EIM83746.1 - 0.059 13.0 0.3 0.099 12.3 0.3 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF1811 PF08838.10 EIM83746.1 - 0.061 13.6 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) dCache_2 PF08269.11 EIM83746.1 - 0.062 12.5 0.2 5.2 6.2 0.1 2.3 1 1 1 2 2 2 0 Cache domain Spore_III_AB PF09548.10 EIM83746.1 - 0.09 12.9 0.3 0.19 11.9 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FGAR-AT_linker PF18072.1 EIM83746.1 - 0.15 12.6 0.2 7.1 7.3 0.0 2.6 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain RuvA_C PF07499.13 EIM83746.1 - 0.15 12.5 0.0 9.7 6.7 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain WH1 PF00568.23 EIM83748.1 - 5.8e-21 74.5 0.0 7.7e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 EIM83748.1 - 4.9e-05 23.6 0.1 9.4e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 EIM83748.1 - 0.00089 19.0 0.2 0.0038 17.0 0.2 2.2 1 0 0 1 1 1 1 WH2 motif Abhydrolase_2 PF02230.16 EIM83748.1 - 0.065 13.0 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DCP1 PF06058.13 EIM83748.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family GFA PF04828.14 EIM83749.1 - 1.3e-08 35.1 13.8 4.2e-08 33.4 0.2 3.1 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme FAD_oxidored PF12831.7 EIM83749.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase PAM2 PF07145.15 EIM83750.1 - 0.039 13.6 0.3 0.085 12.6 0.3 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region OFCC1 PF15680.5 EIM83750.1 - 0.12 13.0 0.1 0.2 12.3 0.1 1.3 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein FA_desaturase PF00487.24 EIM83751.1 - 6.1e-15 55.7 30.9 9.8e-15 55.1 30.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIM83751.1 - 1.5e-14 53.9 0.1 2.7e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_71 PF03659.14 EIM83752.1 - 5.7e-98 328.2 14.0 1.7e-95 320.0 14.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 TRI5 PF06330.11 EIM83754.1 - 0.0014 17.6 0.1 0.003 16.5 0.0 1.5 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) TRI5 PF06330.11 EIM83755.1 - 2.7e-10 39.7 0.3 1e-06 27.9 0.0 2.6 3 0 0 3 3 3 2 Trichodiene synthase (TRI5) Oxidored_FMN PF00724.20 EIM83756.1 - 4e-07 29.6 0.0 0.005 16.2 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.21 EIM83757.1 - 1.6e-43 149.0 0.0 1.8e-41 142.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family FHA PF00498.26 EIM83759.1 - 1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EIM83759.1 - 2.6e-11 43.1 9.2 4.4e-11 42.3 9.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EIM83759.1 - 1.6e-08 34.7 10.3 2.4e-08 34.1 10.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM83759.1 - 5.5e-05 23.0 10.8 8.5e-05 22.3 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM83759.1 - 7.6e-05 22.9 6.6 0.00014 22.1 6.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EIM83759.1 - 0.00011 22.0 11.3 0.00017 21.4 11.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM83759.1 - 0.0003 20.8 2.8 0.00048 20.1 2.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EIM83759.1 - 0.0063 16.4 9.4 0.01 15.8 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.29 EIM83759.1 - 0.051 13.5 5.7 0.09 12.7 5.7 1.3 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 EIM83759.1 - 0.23 11.5 9.9 0.4 10.7 9.9 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM83759.1 - 0.31 11.0 7.5 0.5 10.3 7.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EIM83759.1 - 0.98 9.1 6.0 1.8 8.3 6.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EIM83759.1 - 2.1 8.3 8.9 3.6 7.5 8.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EIM83759.1 - 3.4 7.9 7.0 7.9 6.7 7.1 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SPX PF03105.19 EIM83759.1 - 8.5 6.2 8.0 14 5.5 8.0 1.3 1 0 0 1 1 1 0 SPX domain Acetyltransf_7 PF13508.7 EIM83760.1 - 2.7e-07 30.9 0.3 9.1e-07 29.2 0.3 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM83760.1 - 9e-06 25.9 0.2 1.2e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM83760.1 - 3.8e-05 23.6 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM83760.1 - 0.00013 22.0 0.0 0.0022 18.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM83760.1 - 0.046 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MOZ_SAS PF01853.18 EIM83760.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Peptidase_C14 PF00656.22 EIM83761.1 - 2.8e-18 66.8 0.0 4.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Aldo_ket_red PF00248.21 EIM83762.1 - 2.9e-46 158.0 0.0 2.1e-38 132.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Beach PF02138.18 EIM83763.1 - 1e-106 356.3 0.0 1.7e-106 355.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 EIM83763.1 - 1e-09 38.8 0.2 2.5e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 EIM83763.1 - 6.6e-08 32.6 0.4 2.1e-07 31.0 0.4 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EIM83763.1 - 0.00047 20.9 11.4 0.11 13.4 0.2 4.3 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF4704 PF15787.5 EIM83763.1 - 0.013 14.8 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) ESAG1 PF03238.13 EIM83764.1 - 0.0087 15.5 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 ESAG protein p47_phox_C PF08944.11 EIM83765.1 - 0.012 15.1 0.3 0.022 14.2 0.3 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Transposase_21 PF02992.14 EIM83766.1 - 1.7e-09 37.3 0.0 3.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 EIM83766.1 - 0.00022 20.5 0.5 0.00035 19.9 0.5 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF4218 PF13960.6 EIM83766.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-C2HC5 PF06221.13 EIM83766.1 - 0.73 9.9 3.7 0.22 11.5 0.3 1.9 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.6 EIM83766.1 - 1.5 8.7 5.7 4.5 7.2 0.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Lactamase_B_4 PF13691.6 EIM83770.1 - 0.00014 21.5 0.2 1.4 8.7 0.1 3.4 3 0 0 3 3 3 2 tRNase Z endonuclease HicB_lk_antitox PF15919.5 EIM83770.1 - 0.0011 19.0 0.6 2.6 8.2 0.0 4.3 5 0 0 5 5 5 1 HicB_like antitoxin of bacterial toxin-antitoxin system Phage_attach PF05354.11 EIM83770.1 - 0.17 11.8 1.6 17 5.3 0.1 2.8 3 0 0 3 3 3 0 Phage Head-Tail Attachment ISP1_C PF18161.1 EIM83770.1 - 0.28 11.2 1.3 18 5.4 0.1 3.2 3 0 0 3 3 3 0 ISP1 C-terminal Methyltransf_11 PF08241.12 EIM83771.1 - 1.1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM83771.1 - 4.8e-18 65.7 0.0 7.5e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM83771.1 - 8.4e-11 41.9 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM83771.1 - 6.1e-10 39.7 0.0 9.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM83771.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EIM83771.1 - 5.9e-06 26.2 0.0 8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM83771.1 - 0.024 14.2 0.0 0.092 12.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 EIM83771.1 - 0.11 12.3 0.0 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 EIM83771.1 - 0.25 10.8 0.0 0.5 9.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.22 EIM83773.1 - 3.2e-68 230.6 0.0 4.1e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fer2_3 PF13085.6 EIM83774.1 - 2e-32 111.4 0.0 3e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EIM83774.1 - 8.4e-10 39.1 6.5 8.4e-10 39.1 6.5 2.3 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EIM83774.1 - 3.9e-07 30.1 3.8 3.9e-07 30.1 3.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EIM83774.1 - 3.4e-06 27.4 8.6 3.4e-06 27.4 8.6 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EIM83774.1 - 0.0017 18.9 5.0 0.0017 18.9 5.0 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EIM83774.1 - 0.0069 16.3 1.1 0.0069 16.3 1.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EIM83774.1 - 0.12 12.5 3.9 0.29 11.3 0.0 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EIM83774.1 - 3.9 7.7 14.4 1.1 9.5 8.9 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain zf-MYND PF01753.18 EIM83777.1 - 0.037 14.1 0.9 0.072 13.2 0.9 1.5 1 0 0 1 1 1 0 MYND finger DUF1367 PF07105.11 EIM83777.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1367) Meth_synt_2 PF01717.18 EIM83778.1 - 5.8e-16 58.7 0.0 5.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIM83778.1 - 0.00046 19.8 0.0 0.17 11.4 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain ERM PF00769.19 EIM83780.1 - 0.17 11.7 3.2 0.54 10.0 3.2 1.9 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 EIM83780.1 - 0.2 11.8 4.8 7.5 6.8 0.7 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Profilin PF00235.19 EIM83781.1 - 8.2e-47 158.6 0.8 9.1e-47 158.5 0.8 1.0 1 0 0 1 1 1 1 Profilin Oxidored_FMN PF00724.20 EIM83783.1 - 6.5e-98 328.1 0.0 7.5e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ORC5_C PF14630.6 EIM83784.1 - 1.4e-54 185.6 0.0 2.2e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus ICMT PF04140.14 EIM83788.1 - 4.9e-15 55.7 0.0 6.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM83788.1 - 1.7e-08 34.8 0.3 5.8e-08 33.1 0.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM83788.1 - 0.00096 18.0 0.1 0.077 11.7 0.0 2.1 2 0 0 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 EIM83789.1 - 1.5e-12 47.7 0.0 2.8e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM83789.1 - 4.1e-10 40.0 0.3 2.1e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM83789.1 - 8.8e-07 28.0 0.6 1.7e-06 27.1 0.6 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UPF0126 PF03458.13 EIM83789.1 - 0.0036 17.1 1.4 0.017 15.0 1.4 2.1 1 1 0 1 1 1 1 UPF0126 domain Lipase_GDSL PF00657.22 EIM83790.1 - 1.8e-05 24.8 0.0 2.9e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIM83790.1 - 0.0004 20.8 0.4 0.00083 19.8 0.2 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 EIM83791.1 - 1.4e-07 32.0 9.4 0.019 15.9 0.5 6.5 6 2 1 7 7 7 2 WD domain, G-beta repeat DUF2235 PF09994.9 EIM83792.1 - 5e-70 236.1 0.0 7.6e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.16 EIM83792.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase WD40 PF00400.32 EIM83793.1 - 4.2e-79 258.4 33.9 4.4e-08 33.6 0.0 12.1 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM83793.1 - 1e-27 96.2 0.8 0.0085 16.4 0.0 9.3 1 1 7 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM83793.1 - 1.4e-13 50.5 1.5 0.021 13.8 0.0 7.0 2 2 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EIM83793.1 - 2.6e-06 26.5 1.5 0.49 9.1 0.1 4.9 2 2 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 EIM83793.1 - 4.6e-06 25.6 0.6 7.6 5.0 0.0 5.6 5 1 0 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM83793.1 - 6.4e-06 25.7 0.0 2.5 7.3 0.0 5.2 6 1 0 6 6 6 2 WD40-like domain ELYS-bb PF16687.5 EIM83793.1 - 0.00053 18.7 0.0 0.26 9.8 0.0 3.0 3 1 1 4 4 4 2 beta-propeller of ELYS nucleoporin PD40 PF07676.12 EIM83793.1 - 0.0048 16.8 2.4 3.7 7.6 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 EIM83793.1 - 0.0083 14.5 0.0 2.1 6.6 0.0 3.1 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF5604 PF18300.1 EIM83793.1 - 0.11 12.5 0.1 5 7.2 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5604) Proteasome_A_N PF10584.9 EIM83793.1 - 0.12 12.1 0.0 45 3.9 0.0 4.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Utp8 PF10395.9 EIM83793.1 - 0.28 9.6 0.0 3.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Utp8 family Hemerythrin PF01814.23 EIM83794.1 - 0.00054 20.6 0.1 0.00054 20.6 0.1 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hemerythrin PF01814.23 EIM83795.1 - 0.047 14.3 0.4 0.068 13.8 0.4 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF4436 PF14494.6 EIM83796.1 - 5.8e-13 48.7 1.6 1.1e-12 47.9 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Methyltransf_25 PF13649.6 EIM83797.1 - 5.9e-05 23.7 0.1 0.00018 22.1 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM83797.1 - 0.0056 16.5 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF1890 PF09001.11 EIM83797.1 - 0.029 14.8 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Methyltransf_11 PF08241.12 EIM83797.1 - 0.079 13.6 0.1 0.19 12.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain FAO_M PF16350.5 EIM83797.1 - 0.19 12.1 0.5 2.4 8.5 0.1 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase central domain Meth_synt_2 PF01717.18 EIM83799.1 - 3.5e-15 56.1 0.0 5.5e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIM83799.1 - 2.1e-05 24.2 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain zf-MYND PF01753.18 EIM83800.1 - 6.1e-10 39.0 9.5 2.3e-09 37.2 9.5 2.0 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM83800.1 - 0.039 14.3 7.8 0.11 12.8 7.8 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pil1 PF13805.6 EIM83801.1 - 9.2e-24 84.3 0.9 1.4e-23 83.8 0.9 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3510 PF12022.8 EIM83801.1 - 0.042 14.2 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) CCDC-167 PF15188.6 EIM83801.1 - 0.57 10.6 4.0 1.5 9.2 4.0 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Oxidored_FMN PF00724.20 EIM83802.1 - 7.6e-64 216.1 0.0 1e-63 215.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Meth_synt_2 PF01717.18 EIM83803.1 - 2.7e-11 43.3 0.0 9.3e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIM83803.1 - 0.00021 20.9 0.0 0.036 13.6 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DUF3875 PF12991.7 EIM83803.1 - 0.07 13.1 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) Phytase-like PF13449.6 EIM83805.1 - 1.5e-31 110.4 3.3 4.3e-30 105.7 3.3 2.2 1 1 0 1 1 1 1 Esterase-like activity of phytase MFS_1 PF07690.16 EIM83806.1 - 7.8e-28 97.4 21.5 7.8e-28 97.4 21.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 EIM83806.1 - 0.0045 15.8 0.1 0.01 14.6 0.1 1.5 1 0 0 1 1 1 1 Reduced folate carrier LapA_dom PF06305.11 EIM83806.1 - 0.27 11.1 4.8 0.41 10.5 0.0 3.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain GMC_oxred_N PF00732.19 EIM83807.1 - 2.6e-68 230.6 0.0 3.3e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM83807.1 - 2.7e-33 115.5 0.0 4.7e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM83807.1 - 0.0029 17.8 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM83807.1 - 0.018 14.2 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EIM83807.1 - 0.053 12.7 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.15 EIM83807.1 - 0.11 13.3 0.0 32 5.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Pyr_redox_3 PF13738.6 EIM83807.1 - 0.14 11.4 1.0 2.7 7.2 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM83807.1 - 0.14 11.2 0.4 0.22 10.6 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EIM83807.1 - 0.18 11.0 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family PTR2 PF00854.21 EIM83808.1 - 2.1e-77 260.6 10.6 2.7e-77 260.2 10.6 1.1 1 0 0 1 1 1 1 POT family DUF4293 PF14126.6 EIM83808.1 - 3.2 8.0 5.1 0.99 9.7 0.4 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) Glyco_hydro_cc PF11790.8 EIM83809.1 - 1.2e-37 129.7 1.4 1.5e-37 129.5 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.22 EIM83810.1 - 9.2e-56 185.6 0.0 6.1e-15 54.8 0.0 6.7 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM83810.1 - 2e-08 34.3 0.0 0.12 12.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif Smg4_UPF3 PF03467.15 EIM83810.1 - 0.0016 18.5 1.7 0.71 9.9 0.0 3.9 3 0 0 3 3 3 2 Smg-4/UPF3 family RRM_Rrp7 PF17799.1 EIM83810.1 - 0.0031 17.3 0.0 4.8 7.0 0.0 3.0 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 EIM83810.1 - 0.55 10.4 3.8 32 4.7 0.0 5.0 6 0 0 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter GMC_oxred_N PF00732.19 EIM83811.1 - 7.6e-61 206.1 0.6 1.3e-60 205.3 0.6 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM83811.1 - 3.4e-31 108.7 0.8 6e-31 107.9 0.8 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM83811.1 - 0.00011 21.4 4.2 0.037 13.1 1.6 2.5 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EIM83811.1 - 0.00038 19.6 0.2 0.00066 18.8 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EIM83811.1 - 0.00054 19.7 2.1 0.00054 19.7 2.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM83811.1 - 0.0011 18.2 3.0 0.022 14.0 1.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM83811.1 - 0.0026 18.0 1.9 0.0099 16.1 1.9 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM83811.1 - 0.0026 17.0 0.8 0.0062 15.8 0.8 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EIM83811.1 - 0.03 13.1 3.8 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein AstB PF04996.12 EIM83811.1 - 0.067 11.8 0.1 0.098 11.3 0.1 1.2 1 0 0 1 1 1 0 Succinylarginine dihydrolase Aldo_ket_red PF00248.21 EIM83812.1 - 2.7e-56 190.9 0.2 4.4e-56 190.2 0.2 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family CarbopepD_reg_2 PF13715.6 EIM83812.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain ATLF PF07737.11 EIM83812.1 - 0.22 10.8 0.0 0.75 9.0 0.1 1.8 1 1 1 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain Aldo_ket_red PF00248.21 EIM83814.1 - 3.7e-60 203.6 0.2 4.2e-60 203.4 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 EIM83815.1 - 7.6e-44 150.2 0.0 1.6e-43 149.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EIM83816.1 - 4.9e-40 137.1 0.4 1.6e-32 112.6 0.2 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM83816.1 - 5.2e-23 81.8 0.6 9.9e-22 77.6 0.2 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM83816.1 - 2e-06 27.8 0.1 3e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM83816.1 - 0.033 13.7 0.3 0.15 11.5 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family APH PF01636.23 EIM83817.1 - 8e-09 35.8 0.0 2.4e-08 34.2 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 EIM83817.1 - 0.0045 17.1 8.1 0.0096 16.1 8.1 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger EamA PF00892.20 EIM83818.1 - 3.2e-26 92.1 32.0 4.5e-14 52.8 8.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family MPC PF03650.13 EIM83818.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers DUF2070 PF09843.9 EIM83818.1 - 4.8 5.3 29.3 1.5 7.0 13.2 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) PsbL PF02419.17 EIM83818.1 - 6 6.9 6.1 31 4.7 0.8 2.8 2 0 0 2 2 2 0 PsbL protein SKI PF01202.22 EIM83820.1 - 1.8e-07 31.4 0.0 2.4e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 EIM83820.1 - 0.00015 21.9 0.0 0.00054 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM83820.1 - 0.00052 20.6 0.0 0.0014 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EIM83820.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family Zeta_toxin PF06414.12 EIM83820.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EIM83820.1 - 0.026 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 EIM83820.1 - 0.031 14.7 0.2 0.051 14.0 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EIM83820.1 - 0.046 13.6 0.2 0.32 10.9 0.2 2.1 1 1 1 2 2 2 0 NACHT domain AAA PF00004.29 EIM83820.1 - 0.074 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EIM83820.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EIM83820.1 - 0.11 13.0 0.5 0.28 11.7 0.4 1.6 1 1 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 EIM83820.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase CPT PF07931.12 EIM83820.1 - 0.2 11.5 0.5 10 5.9 0.0 2.8 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein SPICE PF15678.5 EIM83821.1 - 0.044 13.1 0.4 0.05 13.0 0.4 1.0 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Rhodanese PF00581.20 EIM83822.1 - 3.6e-19 69.3 0.3 1.2e-07 32.2 0.0 3.2 3 0 0 3 3 3 3 Rhodanese-like domain DUF4267 PF14087.6 EIM83823.1 - 9.7e-25 86.8 4.6 1.2e-24 86.6 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Ion_trans_2 PF07885.16 EIM83825.1 - 1.9e-25 88.6 33.4 8.8e-14 51.2 10.2 3.2 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 EIM83825.1 - 0.00028 20.8 4.4 0.34 10.7 0.4 3.0 3 1 0 3 3 3 2 Ligand-gated ion channel DUF3087 PF11286.8 EIM83825.1 - 0.037 13.5 0.4 0.096 12.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) MIase PF02426.16 EIM83825.1 - 0.14 12.3 1.1 0.51 10.5 1.1 2.0 1 0 0 1 1 1 0 Muconolactone delta-isomerase G0-G1_switch_2 PF15103.6 EIM83825.1 - 4.1 7.9 6.1 4.4 7.8 0.0 3.8 4 0 0 4 4 4 0 G0/G1 switch protein 2 ATG13 PF10033.9 EIM83826.1 - 7e-48 163.4 0.1 1e-47 162.9 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF4436 PF14494.6 EIM83829.1 - 0.051 12.8 0.0 0.057 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF1176 PF06674.11 EIM83830.1 - 0.1 12.1 0.2 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Peptidase_M14 PF00246.24 EIM83831.1 - 2.7e-65 221.0 1.5 1e-62 212.6 1.5 2.4 1 1 0 1 1 1 1 Zinc carboxypeptidase Pectinesterase PF01095.19 EIM83832.1 - 1.9e-39 135.1 1.4 2.4e-39 134.8 1.4 1.0 1 0 0 1 1 1 1 Pectinesterase Gti1_Pac2 PF09729.9 EIM83833.1 - 6.4e-38 130.6 6.9 2.8e-26 92.7 0.5 3.7 3 1 1 4 4 4 3 Gti1/Pac2 family GST_N_3 PF13417.6 EIM83835.1 - 5.3e-07 30.0 0.0 1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM83835.1 - 5e-06 26.7 0.2 8.4e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM83835.1 - 0.039 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM83835.1 - 0.045 13.8 1.1 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM83835.1 - 0.1 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRR_6 PF13516.6 EIM83836.1 - 5.8e-16 57.1 19.8 0.037 14.1 0.2 9.5 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 EIM83836.1 - 8.2e-09 35.6 10.6 0.045 14.2 0.3 6.4 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIM83836.1 - 0.0085 16.5 9.7 43 5.2 0.0 7.2 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 EIM83836.1 - 0.013 15.2 19.8 2.2 8.1 1.9 6.5 5 2 0 5 5 5 0 Leucine rich repeat AhpC-TSA PF00578.21 EIM83837.1 - 1.4e-19 70.2 0.0 2.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIM83837.1 - 3.5e-10 39.8 0.0 5.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EIM83838.1 - 2.3e-20 72.7 0.0 3.4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIM83838.1 - 1e-09 38.3 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin F-box-like PF12937.7 EIM83839.1 - 5.3e-05 23.0 2.5 7.9e-05 22.5 0.1 2.6 3 1 0 3 3 3 1 F-box-like TAL_FSA PF00923.19 EIM83840.1 - 3.1e-93 312.3 0.1 3.5e-93 312.1 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase p450 PF00067.22 EIM83841.1 - 4.4e-60 203.8 0.0 1.5e-59 202.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF4509 PF14970.6 EIM83841.1 - 0.13 12.2 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Aa_trans PF01490.18 EIM83842.1 - 6.6e-32 110.7 36.3 7.6e-32 110.5 36.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bestrophin PF01062.21 EIM83843.1 - 1.1e-34 120.2 6.2 2e-23 83.2 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Glyco_transf_28 PF03033.20 EIM83843.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain PrgI PF12666.7 EIM83843.1 - 1.8 9.4 4.3 0.76 10.5 0.3 2.2 2 0 0 2 2 2 0 PrgI family protein F-box-like PF12937.7 EIM83844.1 - 1.2e-07 31.5 4.2 7.6e-07 28.9 0.8 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM83844.1 - 0.53 10.2 6.2 3.1 7.8 2.5 3.7 2 1 0 2 2 2 0 F-box domain zinc_ribbon_4 PF13717.6 EIM83845.1 - 0.12 12.3 1.0 0.22 11.5 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.26 EIM83845.1 - 0.41 11.2 6.6 0.16 12.5 3.6 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM83845.1 - 3.6 8.7 4.6 9.7 7.3 4.6 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Glyco_hydro_88 PF07470.13 EIM83846.1 - 2.4e-58 197.9 4.8 3e-58 197.6 4.8 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EIM83846.1 - 0.0023 16.5 0.4 0.83 8.1 0.1 2.5 1 1 1 3 3 3 2 Beta-L-arabinofuranosidase, GH127 HGTP_anticodon PF03129.20 EIM83849.1 - 1.3e-20 73.4 0.0 4.1e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EIM83849.1 - 1.2e-10 41.7 0.0 7.9e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Mucin15 PF15672.5 EIM83850.1 - 0.33 10.4 7.4 0.35 10.3 7.4 1.0 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Pheromone PF08015.11 EIM83850.1 - 0.43 11.7 4.1 0.79 10.8 4.1 1.5 1 1 0 1 1 1 0 Fungal mating-type pheromone ATG27 PF09451.10 EIM83854.1 - 2e-18 67.2 0.0 2.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EIM83854.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat APG12 PF04110.13 EIM83856.1 - 9.6e-32 109.3 0.1 1.1e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EIM83856.1 - 0.0095 16.1 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ELYS PF13934.6 EIM83858.1 - 0.041 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex assembly ThiF PF00899.21 EIM83859.1 - 4.4e-15 55.7 0.0 9e-15 54.7 0.0 1.4 1 1 0 1 1 1 1 ThiF family Nucleoplasmin PF03066.15 EIM83859.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain BTB PF00651.31 EIM83860.1 - 6.9e-06 26.3 0.0 8.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain zf-RanBP PF00641.18 EIM83861.1 - 0.015 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others BTB PF00651.31 EIM83862.1 - 3.2e-09 37.0 0.0 1.7e-08 34.6 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain Sld5 PF05916.11 EIM83863.1 - 0.003 18.0 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 EIM83863.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus BTB PF00651.31 EIM83865.1 - 2.5e-09 37.4 0.1 2.2e-08 34.3 0.0 2.4 2 2 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EIM83866.1 - 2.4e-10 40.6 0.0 3.6e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Y_phosphatase3 PF13350.6 EIM83866.1 - 0.042 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family LysM PF01476.20 EIM83867.1 - 1.9e-09 37.4 0.4 0.0001 22.3 0.2 2.2 2 0 0 2 2 2 2 LysM domain Ribosomal_60s PF00428.19 EIM83867.1 - 0.77 10.4 5.2 1.9 9.1 5.2 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein Epimerase PF01370.21 EIM83869.1 - 4.1e-16 59.2 0.0 8.1e-16 58.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM83869.1 - 3.9e-10 39.6 0.0 6.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM83869.1 - 1.1e-07 31.2 0.0 2.4e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM83869.1 - 1.9e-06 27.2 0.0 4.4e-05 22.8 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EIM83869.1 - 4.7e-05 23.4 0.0 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM83869.1 - 0.00021 20.9 0.2 0.00043 19.9 0.2 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EIM83869.1 - 0.0035 16.8 0.2 0.011 15.2 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase BTB PF00651.31 EIM83870.1 - 7.2e-13 48.7 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain OGFr_N PF04664.13 EIM83871.1 - 1.6e-17 63.8 0.0 2e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Ribosomal_L12 PF00542.19 EIM83871.1 - 0.079 13.3 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain BTB PF00651.31 EIM83872.1 - 1.7e-09 37.9 0.0 5.3e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM83873.1 - 2.1e-09 37.6 0.0 3.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain G-patch PF01585.23 EIM83874.1 - 7.9e-07 28.9 0.6 7.9e-07 28.9 0.6 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EIM83874.1 - 2.1e-05 24.5 0.3 2.1e-05 24.5 0.3 5.0 6 2 0 6 6 6 1 G-patch domain E7 PF00527.18 EIM83878.1 - 0.98 9.7 3.1 2.6 8.3 0.3 2.4 2 1 1 3 3 3 0 E7 protein, Early protein SPX PF03105.19 EIM83879.1 - 1.5e-41 143.6 0.9 2.7e-41 142.8 0.9 1.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EIM83879.1 - 2.6e-07 30.4 5.7 4.4e-07 29.7 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM83879.1 - 4.7e-07 29.6 7.2 7.8e-07 28.9 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM83879.1 - 5.9e-06 26.3 7.0 1e-05 25.6 7.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EIM83879.1 - 7.9e-06 26.1 7.7 1.3e-05 25.4 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EIM83879.1 - 2.4e-05 24.1 6.9 4.2e-05 23.3 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EIM83879.1 - 0.00016 21.4 8.0 0.00028 20.7 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIM83879.1 - 0.00088 19.0 2.8 0.0018 18.0 2.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EIM83879.1 - 0.001 19.0 6.5 0.0021 18.0 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIM83879.1 - 0.0015 18.4 7.3 0.0029 17.5 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 EIM83879.1 - 0.011 15.6 3.2 0.02 14.7 3.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EIM83879.1 - 0.02 15.2 3.7 0.044 14.1 3.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EIM83879.1 - 0.12 12.5 3.6 0.23 11.6 3.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Synaptobrevin PF00957.21 EIM83880.1 - 1.1e-14 54.0 1.1 1.8e-14 53.3 1.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EIM83880.1 - 1.4e-12 47.4 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain TPR_MalT PF17874.1 EIM83880.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 MalT-like TPR region Tetraspanin PF00335.20 EIM83881.1 - 7.6e-07 29.1 2.9 7.6e-07 29.1 2.9 1.5 1 1 0 1 1 1 1 Tetraspanin family ABC2_membrane_3 PF12698.7 EIM83881.1 - 0.018 14.2 5.3 0.03 13.4 5.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF5373 PF17343.2 EIM83881.1 - 0.046 13.6 4.2 0.44 10.4 4.1 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5373) DUF4383 PF14325.6 EIM83881.1 - 0.23 11.7 8.6 6.5 7.0 6.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) DUF202 PF02656.15 EIM83881.1 - 0.36 11.3 0.2 0.36 11.3 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) IspA PF04279.15 EIM83881.1 - 0.5 10.5 5.7 3.8 7.6 5.5 2.0 1 1 0 1 1 1 0 Intracellular septation protein A ADH_N PF08240.12 EIM83882.1 - 0.00035 20.4 0.3 0.0056 16.5 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L38e PF01781.18 EIM83883.1 - 4.6e-34 116.3 1.8 5.3e-34 116.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2344 PF10105.9 EIM83883.1 - 0.048 13.5 0.1 0.091 12.6 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) ADH_zinc_N PF00107.26 EIM83884.1 - 1.1e-13 51.3 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM83884.1 - 5.1e-07 29.5 0.1 3.7e-05 23.6 0.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM83884.1 - 7.1e-06 27.1 0.0 1.5e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Plant_vir_prot PF01307.17 EIM83884.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Plant viral movement protein WD40 PF00400.32 EIM83885.1 - 6e-18 64.9 14.6 1.5e-06 28.8 0.1 6.6 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM83885.1 - 2.7e-07 30.8 0.1 0.35 11.2 0.0 4.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM83885.1 - 0.0094 15.9 0.0 0.04 13.8 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Peptidase_M50 PF02163.22 EIM83886.1 - 8.7e-13 48.1 0.1 2.3e-06 27.1 0.1 2.9 2 1 0 2 2 2 2 Peptidase family M50 Nrap_D4 PF17405.2 EIM83887.1 - 1.7e-50 171.4 0.0 2.9e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 EIM83887.1 - 2.4e-40 138.2 0.3 1.4e-39 135.8 0.3 2.1 1 1 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 EIM83887.1 - 3e-35 121.4 0.0 1.6e-33 115.7 0.0 2.8 2 1 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 EIM83887.1 - 8.4e-35 120.1 0.0 1.6e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 EIM83887.1 - 8.5e-35 119.9 0.0 2.9e-34 118.2 0.0 2.0 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 EIM83887.1 - 5.2e-31 107.5 0.0 1.6e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain ADH_zinc_N PF00107.26 EIM83888.1 - 1.1e-19 70.7 0.0 2.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM83888.1 - 5e-09 36.0 0.0 9.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM83888.1 - 2.4e-07 31.9 0.0 4.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CbiG_N PF11760.8 EIM83888.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal BTB PF00651.31 EIM83889.1 - 3.9e-07 30.3 0.0 8.2e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM83890.1 - 1.4e-09 38.1 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CMAS PF02353.20 EIM83891.1 - 1.5e-63 214.6 0.2 1.8e-63 214.4 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EIM83891.1 - 3.3e-11 43.8 0.0 1e-10 42.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM83891.1 - 5.4e-11 43.0 0.0 2.4e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM83891.1 - 6.6e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM83891.1 - 1.1e-05 26.1 0.0 2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EIM83891.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 EIM83891.1 - 0.0028 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EIM83891.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EIM83891.1 - 0.046 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EIM83891.1 - 0.048 13.7 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EIM83891.1 - 0.18 11.9 0.1 0.45 10.6 0.1 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase CAP59_mtransfer PF11735.8 EIM83892.1 - 6.7e-63 212.6 0.0 8e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 YIF1 PF03878.15 EIM83893.1 - 1.1e-89 300.1 0.1 1.4e-89 299.8 0.1 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EIM83893.1 - 2.8e-06 27.1 1.8 6.2e-06 26.0 1.8 1.5 1 0 0 1 1 1 1 Yip1 domain DUF4131 PF13567.6 EIM83893.1 - 1.1 9.0 6.2 3.6 7.2 6.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) F-box-like PF12937.7 EIM83894.1 - 0.00052 19.8 0.7 0.00052 19.8 0.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM83894.1 - 0.25 11.8 1.4 51 4.5 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) CPL PF08144.11 EIM83895.1 - 4e-33 114.8 0.5 1.5e-28 99.9 0.0 4.0 4 0 0 4 4 4 3 CPL (NUC119) domain Peptidase_S10 PF00450.22 EIM83897.1 - 4.3e-102 342.6 0.1 5.3e-102 342.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EIM83897.1 - 0.076 13.6 0.0 4.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Zn_ribbon_17 PF17120.5 EIM83898.1 - 3e-09 36.4 12.6 8.7e-09 34.9 12.6 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EIM83898.1 - 0.0018 19.0 0.1 0.0018 19.0 0.1 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat C1_2 PF03107.16 EIM83898.1 - 0.17 12.2 8.3 2.8 8.3 8.3 2.4 1 1 0 1 1 1 0 C1 domain DZR PF12773.7 EIM83898.1 - 3.5 7.7 12.1 7.6 6.6 12.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon Glyco_hydro_cc PF11790.8 EIM83899.1 - 2.6e-34 118.9 0.1 3.3e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.8 EIM83901.1 - 4.2e-35 121.4 0.1 4.9e-35 121.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Abhydrolase_6 PF12697.7 EIM83902.1 - 2.9e-13 51.0 0.1 3.7e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2476 PF10630.9 EIM83909.1 - 0.0026 17.9 0.5 0.0058 16.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2476) Catalase PF00199.19 EIM83913.1 - 1.1e-187 623.9 0.1 1.3e-187 623.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EIM83913.1 - 2.7e-16 59.5 0.3 6.6e-16 58.3 0.3 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive vATP-synt_E PF01991.18 EIM83915.1 - 4.1e-55 186.3 9.0 4.8e-55 186.1 9.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF45 PF01863.17 EIM83915.1 - 0.038 14.0 2.6 0.055 13.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 BMC PF00936.19 EIM83915.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 BMC domain GLTP PF08718.11 EIM83915.1 - 0.13 12.6 1.9 0.2 11.9 1.9 1.3 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF883 PF05957.13 EIM83915.1 - 1.3 9.6 9.4 0.34 11.5 3.6 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TFIIB PF00382.19 EIM83916.1 - 3.5e-37 126.3 0.4 5.8e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EIM83916.1 - 6.2e-27 93.9 1.5 6.2e-27 93.9 1.5 2.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EIM83916.1 - 2.7e-08 33.2 2.9 7.2e-08 31.8 2.9 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EIM83916.1 - 2.1e-05 24.2 0.6 0.14 11.9 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DTHCT PF08070.11 EIM83916.1 - 0.0049 17.6 4.2 0.0049 17.6 4.2 2.8 2 0 0 2 2 2 1 DTHCT (NUC029) region HipA_C PF07804.12 EIM83916.1 - 0.043 13.5 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 HipA-like C-terminal domain DZR PF12773.7 EIM83916.1 - 0.05 13.6 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF5407 PF17401.2 EIM83916.1 - 0.31 11.3 0.1 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5407) Asp PF00026.23 EIM83917.1 - 1.4e-35 123.2 10.1 3.6e-35 121.9 10.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM83917.1 - 1.6e-08 35.0 1.4 1.6e-05 25.2 0.3 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Hydantoinase_A PF01968.18 EIM83918.1 - 4.4e-98 328.1 0.0 9.7e-98 327.0 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EIM83918.1 - 1.5e-58 197.4 0.1 1.8e-55 187.4 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 EIM83918.1 - 0.00011 21.9 0.0 0.0087 15.6 0.0 2.9 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family F-box-like PF12937.7 EIM83919.1 - 1.9e-09 37.3 1.0 6.7e-09 35.5 0.1 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM83919.1 - 1.6e-07 31.0 2.3 2e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 F-box domain rRNA_proc-arch PF13234.6 EIM83920.1 - 2.4e-88 296.6 0.1 3.8e-88 295.9 0.1 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EIM83920.1 - 4.2e-53 179.4 0.4 9.1e-53 178.3 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EIM83920.1 - 3.9e-18 65.8 0.6 1.5e-17 63.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM83920.1 - 1.1e-06 29.0 0.0 2.2e-05 24.8 0.0 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM83920.1 - 9.5e-05 22.5 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EIM83920.1 - 0.011 14.8 0.0 0.034 13.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EIM83920.1 - 0.043 14.1 0.0 0.4 11.0 0.0 2.6 2 1 1 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.9 EIM83920.1 - 0.25 11.4 7.0 0.061 13.3 0.7 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3638 PF12340.8 EIM83920.1 - 0.53 9.6 2.4 6.5 6.0 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3638) Ribosomal_L14 PF00238.19 EIM83921.1 - 3.8e-34 117.4 0.0 4.5e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ADH_zinc_N PF00107.26 EIM83922.1 - 2.2e-20 73.0 0.0 3.5e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM83922.1 - 8.3e-13 48.2 0.0 2.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EIM83922.1 - 1.3e-08 35.9 0.0 2.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Macoilin PF09726.9 EIM83923.1 - 2 6.8 7.1 2.1 6.8 7.1 1.0 1 0 0 1 1 1 0 Macoilin family Myosin_N PF02736.19 EIM83924.1 - 1e-11 44.4 1.3 1.4e-11 44.0 1.3 1.2 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_head PF00063.21 EIM83925.1 - 3.7e-50 170.9 0.0 4.1e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EIM83925.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 EIM83925.1 - 0.008 15.1 0.0 0.0099 14.8 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EIM83925.1 - 0.024 15.0 0.0 0.032 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EIM83925.1 - 0.03 14.2 0.1 0.041 13.8 0.1 1.2 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 EIM83925.1 - 0.04 13.9 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EIM83925.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hpr_kinase_C PF07475.12 EIM83925.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_24 PF13479.6 EIM83925.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIM83925.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EIM83925.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EIM83925.1 - 0.15 12.4 0.0 0.33 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.21 EIM83926.1 - 2e-74 251.1 0.0 2.4e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.21 EIM83927.1 - 2.7e-55 187.8 0.0 3.4e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EIM83928.1 - 0.0021 16.0 40.6 0.0027 15.6 40.6 1.2 1 0 0 1 1 1 1 Myosin tail ADIP PF11559.8 EIM83928.1 - 0.023 14.8 4.7 0.023 14.8 4.7 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 EIM83928.1 - 0.094 12.5 22.2 0.086 12.7 6.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 EIM83928.1 - 0.2 11.7 31.9 0.52 10.4 3.5 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EIM83928.1 - 0.25 10.7 29.3 0.18 11.1 18.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 EIM83928.1 - 0.57 10.6 29.0 0.19 12.1 18.3 2.1 1 1 1 2 2 2 0 Fez1 ATG16 PF08614.11 EIM83928.1 - 0.93 9.7 34.2 5.6 7.1 24.8 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 EIM83928.1 - 0.96 8.8 26.8 0.11 11.9 18.9 2.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 EIM83928.1 - 1.1 9.5 20.7 0.52 10.5 0.8 4.0 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 EIM83928.1 - 1.3 9.2 27.1 19 5.5 20.9 3.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2125 PF09898.9 EIM83928.1 - 1.5 8.4 9.4 3 7.4 9.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) ERM PF00769.19 EIM83928.1 - 4.6 7.0 38.4 0.38 10.5 29.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SpecificRecomb PF10136.9 EIM83928.1 - 7.4 4.7 8.7 2.2 6.5 5.2 1.6 1 1 1 2 2 2 0 Site-specific recombinase zf-C4H2 PF10146.9 EIM83928.1 - 7.6 6.8 17.2 14 5.9 17.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4200 PF13863.6 EIM83928.1 - 7.7 7.0 29.6 2.1 8.7 10.6 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) FUSC PF04632.12 EIM83928.1 - 8.3 4.8 17.4 13 4.1 17.1 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Myosin_tail_1 PF01576.19 EIM83929.1 - 4.5e-08 31.4 35.9 1.7e-07 29.5 36.0 1.7 1 1 0 1 1 1 1 Myosin tail ERM PF00769.19 EIM83929.1 - 0.0037 17.1 14.0 0.0037 17.1 14.0 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Fez1 PF06818.15 EIM83929.1 - 0.0094 16.4 31.3 0.38 11.2 15.6 2.0 1 1 1 2 2 2 2 Fez1 Tropomyosin_1 PF12718.7 EIM83929.1 - 0.0096 16.1 31.5 0.16 12.2 19.3 3.2 1 1 1 2 2 2 2 Tropomyosin like Zw10 PF06248.13 EIM83929.1 - 0.037 12.6 8.8 0.059 11.9 8.8 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF5082 PF16888.5 EIM83929.1 - 0.089 13.1 23.1 2.4 8.4 0.8 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) AAA_13 PF13166.6 EIM83929.1 - 0.11 11.1 21.1 0.22 10.1 21.1 1.4 1 1 0 1 1 1 0 AAA domain Filament PF00038.21 EIM83929.1 - 0.23 11.0 31.0 5.2 6.5 19.3 3.1 1 1 1 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 EIM83929.1 - 0.34 10.9 36.1 0.38 10.8 16.6 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 EIM83929.1 - 0.5 10.2 26.8 0.75 9.6 7.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Nsp1_C PF05064.13 EIM83929.1 - 0.57 10.0 19.8 1.1 9.0 5.9 4.0 1 1 3 4 4 4 0 Nsp1-like C-terminal region Vac_Fusion PF02346.16 EIM83929.1 - 0.61 9.8 9.8 0.9 9.2 0.1 3.3 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 BRI3BP PF14965.6 EIM83929.1 - 0.72 9.3 15.9 4.5 6.7 0.8 4.1 3 1 1 4 4 4 0 Negative regulator of p53/TP53 DUF1664 PF07889.12 EIM83929.1 - 1.5 8.9 19.2 4.8 7.2 4.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 EIM83929.1 - 1.9 7.8 32.1 19 4.6 15.9 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding SNARE PF05739.19 EIM83929.1 - 2 8.5 9.0 1.7 8.7 0.2 3.5 4 0 0 4 4 4 0 SNARE domain FPP PF05911.11 EIM83929.1 - 2 6.5 30.4 0.089 11.0 14.5 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fib_alpha PF08702.10 EIM83929.1 - 2.3 8.4 18.5 1.4 9.1 6.3 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 EIM83929.1 - 2.7 8.2 35.3 19 5.4 15.1 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 EIM83929.1 - 4.5 7.7 30.1 4.9 7.6 1.0 5.0 2 2 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 EIM83929.1 - 4.8 7.2 21.2 1.9 8.5 4.7 3.1 1 1 1 2 2 2 0 Laminin Domain II TSNAXIP1_N PF15739.5 EIM83929.1 - 6.2 7.2 23.1 0.061 13.7 4.9 3.2 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus MbeD_MobD PF04899.12 EIM83929.1 - 7.1 6.8 19.2 0.46 10.6 2.8 4.1 2 2 2 4 4 4 0 MbeD/MobD like DUF4407 PF14362.6 EIM83929.1 - 7.9 5.7 23.0 8.4 5.6 11.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SesA PF17107.5 EIM83929.1 - 9.2 6.5 11.8 5.2 7.3 6.5 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HetR_C PF18460.1 EIM83929.1 - 9.3 6.3 8.1 2.4 8.1 0.2 3.2 2 1 3 5 5 5 0 Heterocyst differentiation regulator C-terminal Hood domain OPT PF03169.15 EIM83930.1 - 7.2e-134 447.7 48.8 5e-70 236.8 26.9 2.3 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Ras PF00071.22 EIM83932.1 - 3.4e-34 117.8 0.4 4.1e-34 117.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM83932.1 - 2.4e-25 89.1 0.4 4.3e-25 88.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM83932.1 - 7.5e-08 32.0 0.1 9.5e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIM83932.1 - 5.3e-07 29.2 0.3 6.8e-07 28.9 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EIM83932.1 - 0.011 14.6 0.5 1.3 7.7 0.0 2.2 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 EIM83932.1 - 0.02 14.3 0.0 1.9 7.9 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 EIM83932.1 - 0.038 13.1 1.8 0.13 11.4 0.1 2.2 2 1 1 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EIM83932.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mid2 PF04478.12 EIM83933.1 - 0.022 14.6 0.3 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EIM83933.1 - 0.029 14.3 0.6 0.11 12.4 0.6 2.0 1 1 0 1 1 1 0 TMEM154 protein family FAM176 PF14851.6 EIM83933.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 FAM176 family Glyco_hydro_7 PF00840.20 EIM83934.1 - 5.7e-199 661.3 3.9 6.4e-199 661.1 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF1467 PF07330.12 EIM83935.1 - 0.2 11.6 1.4 0.48 10.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) ADH_zinc_N PF00107.26 EIM83937.1 - 3.6e-20 72.3 0.0 5.6e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM83937.1 - 3.3e-12 46.3 0.0 1.1e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EIM83937.1 - 4.9e-09 37.3 0.0 8.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EIF_2_alpha PF07541.12 EIM83938.1 - 0.082 13.0 0.1 0.096 12.8 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Ribosomal_L6 PF00347.23 EIM83938.1 - 0.11 13.1 1.4 0.17 12.6 1.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L6 RRM_1 PF00076.22 EIM83939.1 - 5.1e-17 61.5 0.0 7.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM83939.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM83939.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif ADH_N_2 PF16884.5 EIM83940.1 - 2.7e-23 81.9 0.0 5.9e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EIM83940.1 - 5.8e-21 74.8 0.0 1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM83940.1 - 3.1e-07 31.5 0.0 6.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EIM83940.1 - 0.11 12.2 0.1 0.41 10.4 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2855) CBM77 PF18283.1 EIM83941.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding module 77 Peptidase_C14 PF00656.22 EIM83942.1 - 1.4e-25 90.6 0.0 2.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain HAD_2 PF13419.6 EIM83943.1 - 5.7e-16 59.1 0.0 7.7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM83943.1 - 2.5e-09 37.7 0.0 3.9e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM83943.1 - 5.3e-06 26.4 0.0 9.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EIM83943.1 - 0.073 13.2 0.0 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_L12_N PF16320.5 EIM83943.1 - 0.3 10.8 0.1 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain FAD-oxidase_C PF02913.19 EIM83944.1 - 3.1e-57 194.1 0.0 6e-57 193.1 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EIM83944.1 - 8.2e-30 103.4 0.0 1.5e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain E1-E2_ATPase PF00122.20 EIM83945.1 - 3.2e-19 69.1 0.0 1.5e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EIM83945.1 - 7.3e-14 52.5 0.6 1e-06 29.2 1.3 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIM83945.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIM83945.1 - 0.045 13.5 0.1 0.09 12.5 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pox_P21 PF05313.12 EIM83945.1 - 0.47 10.0 3.3 0.98 9.0 3.3 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein UQ_con PF00179.26 EIM83946.1 - 9.3e-34 116.1 0.0 2.5e-33 114.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme ADH_zinc_N PF00107.26 EIM83947.1 - 1.3e-21 76.9 0.0 2.1e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM83947.1 - 3e-11 43.2 0.0 6.3e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EIM83947.1 - 1e-09 39.5 0.0 1.7e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2236 PF09995.9 EIM83948.1 - 1.3e-13 51.7 0.1 2.5e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Pyr_redox_2 PF07992.14 EIM83952.1 - 1.9e-48 165.2 0.0 2.4e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM83952.1 - 1.7e-09 38.1 0.0 2.6e-08 34.3 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM83952.1 - 0.035 13.4 0.5 0.17 11.1 0.5 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3524 PF12038.8 EIM83952.1 - 0.21 11.4 0.2 9.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) Glyco_hyd_65N_2 PF14498.6 EIM83954.1 - 3e-46 158.2 0.4 5.5e-46 157.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Phage_TTP_12 PF16461.5 EIM83954.1 - 0.024 14.3 1.3 0.06 13.1 0.1 2.3 3 0 0 3 3 3 0 Lambda phage tail tube protein, TTP FMO-like PF00743.19 EIM83955.1 - 2e-29 102.5 0.0 5.2e-21 74.7 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM83955.1 - 2.9e-11 43.2 0.2 2.8e-09 36.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM83955.1 - 2.2e-09 36.9 0.1 1.3e-05 24.5 0.0 3.3 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIM83955.1 - 6.5e-07 28.9 0.0 1.9e-05 24.0 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM83955.1 - 1e-06 28.8 0.5 0.00018 21.5 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EIM83955.1 - 0.001 19.2 0.4 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Planc_extracel PF07595.12 EIM83955.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Planctomycete extracellular Thi4 PF01946.17 EIM83955.1 - 0.17 11.1 0.2 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 EIM83955.1 - 0.21 12.0 0.4 7.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding F-box PF00646.33 EIM83958.1 - 0.0019 18.1 0.2 0.0099 15.7 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM83958.1 - 0.024 14.5 1.9 0.038 13.9 0.2 2.4 3 0 0 3 3 3 0 F-box-like EPSP_synthase PF00275.20 EIM83959.1 - 1.6e-120 402.6 0.0 2.4e-120 402.0 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EIM83959.1 - 2e-99 332.0 0.0 6.4e-99 330.4 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EIM83959.1 - 2.4e-54 185.0 0.0 3.7e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EIM83959.1 - 2e-30 106.0 0.0 2.5e-29 102.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EIM83959.1 - 1.6e-24 85.9 0.0 4.2e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EIM83959.1 - 4.1e-09 36.5 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EIM83959.1 - 3.5e-07 29.9 0.1 1.1e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EIM83959.1 - 2.8e-06 27.5 0.0 9.4e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EIM83959.1 - 0.016 15.5 0.0 0.6 10.4 0.0 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 EIM83959.1 - 0.14 12.6 0.0 0.6 10.5 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain Methyltransf_2 PF00891.18 EIM83960.1 - 5.8e-21 74.8 0.1 6.9e-17 61.4 0.0 2.4 2 1 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 EIM83960.1 - 0.013 16.2 0.0 0.025 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RCC1 PF00415.18 EIM83961.1 - 1.1e-47 160.4 9.0 2e-09 37.9 0.2 8.7 8 2 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIM83961.1 - 3.5e-27 93.6 30.7 1.4e-05 24.8 0.8 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EIM83961.1 - 0.022 14.5 0.0 0.88 9.2 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split S4 PF01479.25 EIM83962.1 - 1.7e-11 43.6 0.1 3.3e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EIM83962.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 S4 domain AF-4 PF05110.13 EIM83962.1 - 0.59 8.2 9.7 0.81 7.7 9.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Astro_capsid_p PF12226.8 EIM83962.1 - 0.89 8.7 5.1 1.3 8.1 5.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ferric_reduct PF01794.19 EIM83963.1 - 5.8e-19 68.4 4.6 1.3e-18 67.3 4.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIM83963.1 - 3.6e-07 30.2 0.0 6.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EIM83963.1 - 4.2e-07 30.2 0.0 1.6e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EIM83963.1 - 0.042 14.5 0.0 0.2 12.3 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1761 PF08570.10 EIM83964.1 - 0.0023 18.2 1.0 0.0023 18.2 1.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1761) UPF0139 PF03669.13 EIM83964.1 - 0.1 12.5 0.2 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Cation_efflux PF01545.21 EIM83964.1 - 0.16 11.7 7.3 0.33 10.6 7.1 1.7 1 1 0 1 1 1 0 Cation efflux family ADH_zinc_N_2 PF13602.6 EIM83965.1 - 1.8e-21 77.6 0.0 5e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EIM83965.1 - 1.1e-16 60.9 0.0 1.8e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM83965.1 - 0.0039 16.7 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 EIM83965.1 - 0.045 13.7 0.5 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase SPT_ssu-like PF11779.8 EIM83966.1 - 4.6e-13 48.6 7.2 6.2e-13 48.1 7.2 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like GCP_N_terminal PF17681.1 EIM83967.1 - 3e-63 214.3 0.0 1.8e-62 211.7 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EIM83967.1 - 1.5e-56 192.1 5.0 1.5e-56 192.1 5.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal ADH_zinc_N_2 PF13602.6 EIM83968.1 - 5.8e-21 75.9 0.0 1.1e-20 75.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HMG_box PF00505.19 EIM83968.1 - 3.7e-15 56.1 5.0 1.5e-09 38.2 0.1 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box ADH_zinc_N PF00107.26 EIM83968.1 - 2.3e-14 53.5 0.0 4.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HMG_box_2 PF09011.10 EIM83968.1 - 9.4e-12 45.4 11.7 2.5e-06 28.0 0.1 2.7 3 0 0 3 3 3 2 HMG-box domain DUF3460 PF11943.8 EIM83968.1 - 0.02 15.1 0.1 0.051 13.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) FAD_binding_3 PF01494.19 EIM83969.1 - 4.2e-15 55.8 0.0 9e-15 54.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM83969.1 - 2.7e-06 27.2 5.4 0.0029 17.3 0.4 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM83969.1 - 6.4e-06 26.2 0.5 3.1e-05 24.0 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EIM83969.1 - 1.4e-05 24.5 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM83969.1 - 0.0001 22.4 0.1 0.00028 21.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIM83969.1 - 0.00032 20.1 1.0 0.016 14.5 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EIM83969.1 - 0.00097 18.1 0.3 0.4 9.5 0.3 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 EIM83969.1 - 0.0017 17.5 1.3 0.0035 16.5 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EIM83969.1 - 0.0022 17.3 0.2 0.0036 16.6 0.2 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EIM83969.1 - 0.0051 15.6 0.1 2.3 6.8 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EIM83969.1 - 0.13 12.8 0.2 1.9 9.1 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM83969.1 - 0.24 10.7 0.2 0.42 9.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EIM83969.1 - 0.27 10.4 0.7 2.6 7.2 0.1 2.7 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Nuclease_act PF08133.11 EIM83969.1 - 0.42 10.9 1.7 0.92 9.8 0.2 2.2 2 0 0 2 2 2 0 Anticodon nuclease activator family Acetyltransf_1 PF00583.25 EIM83970.1 - 7.2e-08 32.7 0.0 2.3e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM83970.1 - 2.8e-06 27.6 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM83970.1 - 6.1e-06 26.2 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM83970.1 - 0.0021 18.2 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NMT PF01233.19 EIM83970.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_13 PF13880.6 EIM83970.1 - 0.031 14.2 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 EIM83970.1 - 0.053 13.6 0.1 0.2 11.8 0.0 2.0 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EIM83970.1 - 0.091 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein AP_endonuc_2 PF01261.24 EIM83971.1 - 2.2e-28 99.1 0.0 3.6e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_16 PF00722.21 EIM83972.1 - 7.9e-13 48.3 0.3 1.5e-12 47.4 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DctQ PF04290.12 EIM83972.1 - 0.071 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Glyco_trans_2_3 PF13632.6 EIM83973.1 - 1.1e-57 195.2 0.7 1.1e-57 195.2 0.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIM83973.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIM83973.1 - 0.0005 19.9 0.1 0.044 13.6 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIM83973.1 - 0.091 12.2 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 CUE PF02845.16 EIM83974.1 - 9e-08 31.7 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 EIM83974.1 - 0.074 13.1 2.1 0.16 12.1 2.1 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Pkinase PF00069.25 EIM83975.1 - 6.2e-71 238.8 0.0 7.9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM83975.1 - 3.8e-33 114.9 0.0 5.2e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EIM83975.1 - 3.4e-12 46.9 1.7 3.4e-12 46.9 1.7 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EIM83975.1 - 5.8e-06 25.5 0.0 9.4e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIM83975.1 - 0.00031 20.1 0.0 0.0013 18.1 0.0 2.0 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 EIM83975.1 - 0.046 13.4 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIM83975.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM83975.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family C2 PF00168.30 EIM83975.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 C2 domain SNARE PF05739.19 EIM83978.1 - 2.9e-09 36.8 0.4 5.7e-09 35.8 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.13 EIM83978.1 - 0.018 14.9 0.3 0.018 14.9 0.3 2.3 2 1 1 3 3 3 0 Sec20 Fusion_gly PF00523.18 EIM83978.1 - 0.035 12.4 0.2 0.056 11.7 0.2 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 KxDL PF10241.9 EIM83978.1 - 0.079 13.2 1.3 0.25 11.7 1.3 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein Tropomyosin PF00261.20 EIM83978.1 - 0.19 11.1 2.5 0.23 10.8 0.8 1.8 2 0 0 2 2 2 0 Tropomyosin Flp1_like PF16982.5 EIM83978.1 - 0.45 9.9 5.4 0.83 9.1 5.4 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF4763 PF15960.5 EIM83978.1 - 0.46 9.8 6.6 0.37 10.1 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) TolA_bind_tri PF16331.5 EIM83978.1 - 1.5 9.0 9.8 3 8.0 0.6 3.5 3 1 1 4 4 4 0 TolA binding protein trimerisation GATase PF00117.28 EIM83979.1 - 4.2e-06 26.7 0.0 2.4e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIM83979.1 - 0.17 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase C26 DIOX_N PF14226.6 EIM83980.1 - 1.3e-16 61.4 0.0 2.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM83980.1 - 1.4e-11 44.7 0.0 3.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4093 PF13331.6 EIM83980.1 - 0.16 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Mito_carr PF00153.27 EIM83981.1 - 5.1e-54 180.2 0.5 1.4e-16 60.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein NmrA PF05368.13 EIM83982.1 - 2.8e-49 167.8 0.0 3.3e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM83982.1 - 5.3e-18 65.6 0.0 1.2e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM83982.1 - 8.2e-06 25.4 0.0 2.9e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM83982.1 - 0.00025 20.2 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EIM83982.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 EIM83982.1 - 0.031 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PepSY_TM PF03929.16 EIM83983.1 - 0.011 15.4 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 0 PepSY-associated TM region MFS_1 PF07690.16 EIM83984.1 - 9.1e-40 136.6 28.8 9.1e-40 136.6 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM83984.1 - 1.1e-13 50.9 8.8 1.1e-13 50.9 8.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EIM83984.1 - 0.00014 20.5 1.5 0.00014 20.5 1.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EIM83984.1 - 0.00015 21.2 1.3 0.00015 21.2 1.3 2.4 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB rpo132 PF12415.8 EIM83984.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase Aldo_ket_red PF00248.21 EIM83985.1 - 4.1e-43 147.7 0.0 7.6e-43 146.8 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Ish1 PF10281.9 EIM83985.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Aldo_ket_red PF00248.21 EIM83986.1 - 4.4e-43 147.6 0.0 5.8e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 EIM83988.1 - 4.8e-17 62.2 0.0 8.1e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM83988.1 - 5.5e-08 32.9 0.5 1.1e-07 31.9 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM83988.1 - 1e-06 28.1 0.1 1.6e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM83988.1 - 3.7e-06 26.8 0.3 0.00036 20.2 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM83988.1 - 0.0043 16.2 0.2 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 EIM83988.1 - 0.0047 17.5 0.2 0.011 16.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM83988.1 - 0.0059 15.3 0.0 0.0089 14.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM83988.1 - 0.0064 15.8 0.3 0.014 14.6 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EIM83988.1 - 0.018 14.4 0.1 0.31 10.3 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 EIM83988.1 - 0.068 12.2 0.6 0.1 11.6 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EIM83988.1 - 0.073 13.1 0.1 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EIM83988.1 - 0.08 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM83988.1 - 0.091 12.0 1.3 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Abhydrolase_1 PF00561.20 EIM83989.1 - 4.2e-11 43.0 0.0 1.6e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM83989.1 - 4.9e-08 32.5 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 EIM83990.1 - 8.3e-39 133.5 0.0 6.7e-37 127.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RNase_P_p30 PF01876.16 EIM83991.1 - 1.7e-34 119.2 0.0 2.4e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Ndc1_Nup PF09531.10 EIM83992.1 - 4e-71 240.5 0.0 6e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Paf67 PF10255.9 EIM83993.1 - 2.1e-167 557.2 0.0 2.7e-167 556.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_16 PF13432.6 EIM83993.1 - 0.0039 17.8 0.0 4.8 7.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM83993.1 - 0.033 14.3 0.0 0.41 10.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM83993.1 - 0.11 12.7 0.0 0.44 10.8 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PAP_assoc PF03828.19 EIM83995.1 - 5.4e-05 23.3 0.0 0.0016 18.6 0.0 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EIM83995.1 - 0.00045 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.11 EIM83995.1 - 0.0056 16.9 1.2 0.33 11.2 0.1 2.8 3 0 0 3 3 3 1 tRNA nucleotidyltransferase, second domain F-box-like PF12937.7 EIM83996.1 - 3e-08 33.4 0.7 1.3e-07 31.4 0.7 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM83996.1 - 0.0073 16.2 5.1 0.017 15.0 2.0 3.0 2 1 0 2 2 2 1 F-box domain Solute_trans_a PF03619.16 EIM83997.1 - 4e-93 311.8 10.5 5e-93 311.5 10.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-MYND PF01753.18 EIM84000.1 - 4e-08 33.2 11.4 4e-08 33.2 11.4 2.0 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EIM84000.1 - 1.2 9.5 7.1 2.5 8.5 7.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding C2 PF00168.30 EIM84001.1 - 2.3e-28 98.5 0.0 1.5e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain Inhibitor_I78 PF11720.8 EIM84003.1 - 0.045 13.8 0.2 0.09 12.9 0.2 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I78 family Med8 PF10232.9 EIM84004.1 - 7.6e-07 29.0 3.5 1.5e-06 28.0 3.5 1.4 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 QRPTase_C PF01729.19 EIM84004.1 - 0.0028 17.5 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Herpes_UL37_1 PF03970.13 EIM84004.1 - 0.084 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein F-box-like PF12937.7 EIM84005.1 - 8.8e-06 25.5 2.0 6.3e-05 22.8 0.2 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM84005.1 - 1.4 8.9 6.3 13 5.8 0.6 4.0 3 1 0 3 3 3 0 F-box domain NmrA PF05368.13 EIM84006.1 - 4.1e-38 131.3 0.0 8.4e-38 130.2 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EIM84006.1 - 1.6e-12 47.7 0.0 2.4e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM84006.1 - 0.087 12.3 0.1 0.25 10.8 0.0 1.8 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Rib_5-P_isom_A PF06026.14 EIM84007.1 - 3.1e-58 196.2 0.0 4e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Tfb5 PF06331.12 EIM84008.1 - 4.5e-16 58.6 1.0 4.7e-16 58.5 1.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Binary_toxB_3 PF17476.2 EIM84008.1 - 0.05 13.8 0.2 0.052 13.7 0.2 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 dsrm PF00035.26 EIM84010.1 - 0.00011 22.8 0.0 0.00032 21.4 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF4692 PF15763.5 EIM84010.1 - 0.079 13.4 0.4 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) MitMem_reg PF13012.6 EIM84010.1 - 0.17 12.3 0.1 0.62 10.5 0.0 1.8 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Pex19 PF04614.12 EIM84011.1 - 6.8e-57 193.0 9.8 6.8e-57 193.0 9.8 1.4 2 0 0 2 2 2 1 Pex19 protein family Macro PF01661.21 EIM84011.1 - 0.079 13.0 0.1 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 Macro domain RGS PF00615.19 EIM84012.1 - 2.3e-08 34.3 0.8 0.0015 18.8 0.1 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain DUF2516 PF10724.9 EIM84012.1 - 0.67 10.3 5.3 0.62 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) L51_S25_CI-B8 PF05047.16 EIM84013.1 - 5.8e-13 48.5 0.0 8.3e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NmrA PF05368.13 EIM84014.1 - 8.6e-37 126.9 0.0 1.2e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM84014.1 - 6.7e-11 42.4 0.0 9.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM84014.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 EIM84015.1 - 3.9e-06 26.7 0.5 1.1e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like CHAT PF12770.7 EIM84016.1 - 4.1e-27 95.3 0.1 9.8e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_14 PF13428.6 EIM84016.1 - 0.068 14.0 3.6 9.8 7.3 0.0 4.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM84016.1 - 0.95 9.4 8.7 6.5 6.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 EIM84017.1 - 2.5e-56 191.4 0.0 3.3e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.25 EIM84018.1 - 7.1e-62 209.1 0.0 8.9e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM84018.1 - 6.1e-29 101.1 0.0 8.3e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM84018.1 - 3.8e-07 29.7 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM84018.1 - 0.006 16.5 0.1 0.021 14.8 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM84018.1 - 0.029 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EIM84018.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.21 EIM84019.1 - 4.4e-48 164.0 0.0 5e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMGL-like PF00682.19 EIM84020.1 - 5.1e-65 219.7 0.0 1.1e-64 218.6 0.0 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EIM84020.1 - 1e-12 48.1 0.3 2.1e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain MFS_1 PF07690.16 EIM84021.1 - 2.6e-43 148.3 24.7 2.6e-43 148.3 24.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM84021.1 - 1.5e-12 47.2 0.4 1.5e-12 47.2 0.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EIM84021.1 - 3.2e-05 22.5 0.7 5.2e-05 21.9 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EIM84021.1 - 0.00022 19.8 1.6 0.00039 19.0 1.6 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector LysM PF01476.20 EIM84022.1 - 2.4e-07 30.7 0.1 2.6e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 LysM domain APH PF01636.23 EIM84023.1 - 6.8e-05 22.9 1.3 0.00019 21.4 1.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Med9 PF07544.13 EIM84024.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 RC-P840_PscD PF10657.9 EIM84025.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD MFS_1 PF07690.16 EIM84026.1 - 2.1e-16 59.8 28.6 3.1e-16 59.3 28.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Abdominal-A PF12407.8 EIM84026.1 - 2.7 7.7 7.6 4.3 7.0 7.6 1.3 1 0 0 1 1 1 0 Homeobox protein CRAL_TRIO PF00650.20 EIM84028.1 - 2.3e-35 121.7 0.0 4e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIM84028.1 - 4.8e-09 36.3 0.9 1.1e-08 35.1 0.9 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain LapA_dom PF06305.11 EIM84029.1 - 0.013 15.3 2.3 0.4 10.5 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Phage_holin_5_2 PF16079.5 EIM84029.1 - 0.14 12.5 5.1 0.09 13.1 1.4 2.2 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF202 PF02656.15 EIM84029.1 - 7 7.2 10.3 17 6.0 0.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Alpha-amylase PF00128.24 EIM84030.1 - 6.6e-117 390.8 0.2 5.8e-116 387.7 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EIM84030.1 - 8.5e-08 32.2 0.0 2.3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Cyc-maltodext_C PF10438.9 EIM84030.1 - 0.0009 19.3 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain hDGE_amylase PF14701.6 EIM84030.1 - 0.003 16.7 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 EIM84030.1 - 0.0036 17.0 0.3 0.011 15.5 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase C-terminal domain AA_permease PF00324.21 EIM84031.1 - 1.9e-117 392.8 34.7 2.3e-117 392.6 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM84031.1 - 2.6e-37 128.7 34.7 3.2e-37 128.4 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.12 EIM84031.1 - 0.044 14.0 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) PBP PF01161.20 EIM84033.1 - 2.6e-18 66.6 0.0 3.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GlyL_C PF12524.8 EIM84033.1 - 6.9 6.9 6.7 7.3 6.8 0.5 2.9 2 1 1 3 3 3 0 dsDNA virus glycoprotein L C terminal DUF4224 PF13986.6 EIM84034.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Zn_clus PF00172.18 EIM84035.1 - 0.017 15.2 0.5 0.017 15.2 0.5 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Integrase_H2C2 PF17921.1 EIM84037.1 - 4.4e-16 58.7 2.7 9.3e-16 57.7 2.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIM84037.1 - 0.0064 16.7 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Rubella_E1 PF05748.11 EIM84037.1 - 0.041 12.8 0.1 0.055 12.3 0.1 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 zf-C2H2_10 PF16588.5 EIM84038.1 - 0.3 10.9 7.9 0.4 10.5 4.6 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-TFIIB PF13453.6 EIM84038.1 - 5.6 6.4 9.4 0.84 9.0 4.7 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger ArfGap PF01412.18 EIM84038.1 - 6.6 6.8 11.9 14 5.8 12.0 1.4 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf RVT_1 PF00078.27 EIM84039.1 - 6.3e-08 32.4 0.0 6.7e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 EIM84040.1 - 2.6e-14 53.3 0.1 1.3e-13 51.0 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIM84040.1 - 1.3e-05 25.0 9.7 0.0043 17.1 2.3 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.6 EIM84040.1 - 0.0062 16.4 2.7 0.014 15.3 2.7 1.5 1 0 0 1 1 1 1 Nudix N-terminal Lectin_N PF03954.14 EIM84040.1 - 0.15 11.8 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 EIM84040.1 - 0.81 10.2 4.6 4.8 7.7 0.9 3.6 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-CCHC_5 PF14787.6 EIM84040.1 - 4.1 7.2 6.3 12 5.8 0.2 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RNase_H PF00075.24 EIM84041.1 - 0.00011 22.5 0.2 0.00021 21.5 0.0 1.5 2 0 0 2 2 2 1 RNase H DUF3756 PF12581.8 EIM84041.1 - 0.076 12.9 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) gag-asp_proteas PF13975.6 EIM84042.1 - 0.00013 22.4 0.0 0.00042 20.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIM84042.1 - 0.006 17.2 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 EIM84042.1 - 0.092 12.6 0.7 0.19 11.6 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.6 EIM84043.1 - 0.0031 17.3 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease EF_TS PF00889.19 EIM84043.1 - 0.22 11.1 0.0 0.44 10.1 0.0 1.5 1 1 0 1 1 1 0 Elongation factor TS WD40 PF00400.32 EIM84044.1 - 3.9e-119 385.1 41.6 9.3e-10 39.0 0.2 13.4 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM84044.1 - 9.1e-37 125.2 19.4 0.0027 17.9 0.1 11.5 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIM84044.1 - 6.2e-12 45.5 4.5 0.025 13.9 0.0 6.7 1 1 7 9 9 9 3 WD40-like domain Me-amine-dh_H PF06433.11 EIM84044.1 - 2.8e-11 42.9 5.1 0.081 11.8 0.1 5.4 3 1 3 6 6 6 4 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 EIM84044.1 - 6.3e-10 38.5 23.1 0.1 11.6 0.0 9.6 1 1 9 10 10 10 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EIM84044.1 - 3.5e-09 35.7 21.7 0.0012 17.5 0.6 6.4 1 1 6 8 8 8 4 Cytochrome D1 heme domain NACHT PF05729.12 EIM84044.1 - 1.1e-06 28.7 0.0 2.8e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EIM84044.1 - 5.7e-06 26.8 0.0 9.3e-05 22.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain PQQ PF01011.21 EIM84044.1 - 7e-06 25.7 0.0 10 6.3 0.0 6.6 7 0 0 7 7 7 0 PQQ enzyme repeat Frtz PF11768.8 EIM84044.1 - 0.0012 17.3 4.1 15 3.8 0.0 5.9 5 2 2 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz Big_7 PF17957.1 EIM84044.1 - 0.0017 19.1 27.2 5.3 7.9 0.0 9.2 7 2 1 9 9 8 1 Bacterial Ig domain PLD_C PF12357.8 EIM84044.1 - 0.0076 16.1 0.3 62 3.6 0.0 5.6 5 1 1 6 6 6 0 Phospholipase D C terminal AAA PF00004.29 EIM84044.1 - 0.0088 16.5 0.0 0.031 14.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1258 PF06869.12 EIM84044.1 - 0.019 14.4 0.0 3.7 7.0 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1258) VID27 PF08553.10 EIM84044.1 - 0.036 13.1 1.6 1.7 7.6 0.0 3.9 2 1 2 5 5 5 0 VID27 C-terminal WD40-like domain NB-ARC PF00931.22 EIM84044.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 EIM84044.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 EIM84044.1 - 0.15 12.5 0.3 1.3 9.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase DUF4909 PF16253.5 EIM84044.1 - 0.2 11.5 3.7 1.1e+02 2.6 0.0 5.4 8 0 0 8 8 7 0 Domain of unknown function (DUF4909) Nop14 PF04147.12 EIM84045.1 - 0.25 9.5 40.3 0.38 8.9 40.3 1.3 1 0 0 1 1 1 0 Nop14-like family LysM PF01476.20 EIM84046.1 - 1.8e-13 50.3 0.0 3.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 LysM domain PfkB PF00294.24 EIM84047.1 - 3.9e-30 105.2 0.0 6.1e-29 101.3 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HpcH_HpaI PF03328.14 EIM84048.1 - 1e-28 100.0 0.2 1.2e-28 99.8 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Sugar_tr PF00083.24 EIM84049.1 - 6.6e-102 341.7 18.7 7.6e-102 341.5 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM84049.1 - 2.2e-30 105.8 24.1 1.8e-29 102.8 20.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM84049.1 - 4.1e-05 22.2 1.6 4.1e-05 22.2 1.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EIM84049.1 - 0.069 11.4 5.2 0.34 9.1 1.9 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family LysM PF01476.20 EIM84050.1 - 1.3e-14 54.0 0.0 2.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 LysM domain GF_recep_IV PF14843.6 EIM84050.1 - 0.02 14.7 2.6 0.026 14.3 2.6 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV EGF_3 PF12947.7 EIM84050.1 - 0.51 10.6 4.1 1.2 9.4 0.4 2.6 2 1 0 2 2 2 0 EGF domain FAD_binding_3 PF01494.19 EIM84051.1 - 8.6e-12 45.0 0.3 2e-07 30.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain WD40 PF00400.32 EIM84053.1 - 4.8e-122 394.3 35.1 7.9e-11 42.3 0.0 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM84053.1 - 1e-38 131.5 12.0 0.0017 18.6 0.0 11.6 1 1 9 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EIM84053.1 - 6e-13 48.1 18.6 0.0011 17.5 0.3 6.2 1 1 6 8 8 8 8 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 EIM84053.1 - 8.8e-12 44.5 4.7 0.19 10.5 0.0 7.1 3 1 5 9 9 9 4 Methylamine dehydrogenase heavy chain (MADH) Frtz PF11768.8 EIM84053.1 - 5.3e-10 38.2 0.1 1.8 6.8 0.0 7.6 4 3 3 8 8 8 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 EIM84053.1 - 2.1e-09 36.9 0.0 45 4.2 0.0 10.5 12 0 0 12 12 12 0 PQQ enzyme repeat NACHT PF05729.12 EIM84053.1 - 3.3e-07 30.4 0.0 8.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain CHAP PF05257.16 EIM84053.1 - 1.4e-05 25.6 16.4 4.6 7.9 0.0 9.1 1 1 6 8 8 8 1 CHAP domain Ge1_WD40 PF16529.5 EIM84053.1 - 1.6e-05 24.1 7.1 1.6 7.7 0.0 7.1 2 2 4 8 8 8 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EIM84053.1 - 6.2e-05 23.4 0.0 0.00037 20.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain PQQ_3 PF13570.6 EIM84053.1 - 0.0002 21.7 16.4 50 4.6 0.0 9.9 9 2 2 11 11 10 0 PQQ-like domain WD40_like PF17005.5 EIM84053.1 - 0.00089 18.7 0.0 16 4.7 0.0 5.1 5 2 1 6 6 6 0 WD40-like domain AAA PF00004.29 EIM84053.1 - 0.0081 16.6 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EIM84053.1 - 0.053 12.7 0.0 0.26 10.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain PD40 PF07676.12 EIM84053.1 - 0.56 10.2 23.5 17 5.5 0.0 9.6 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat p450 PF00067.22 EIM84054.1 - 2e-64 218.0 0.0 1.1e-62 212.4 0.0 3.0 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 EIM84055.1 - 1e-27 97.4 0.8 9.7e-17 61.3 1.5 3.0 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM84055.1 - 0.0025 18.1 6.4 0.015 15.5 0.2 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Fungal_trans PF04082.18 EIM84057.1 - 9.9e-22 77.2 0.0 1.7e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM84057.1 - 2.1e-09 37.3 11.1 4.1e-09 36.4 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 EIM84059.1 - 0.008 16.6 4.7 6.6 7.3 0.1 4.3 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) PhoLip_ATPase_C PF16212.5 EIM84060.1 - 7.6e-70 235.5 32.8 7.6e-70 235.5 32.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIM84060.1 - 7.6e-23 80.0 0.9 7.6e-23 80.0 0.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EIM84060.1 - 4e-12 46.1 0.0 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EIM84060.1 - 4.7e-12 46.6 0.2 2.3e-06 28.1 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EIM84060.1 - 7.7e-07 28.8 5.9 2.7e-05 23.8 0.0 3.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EIM84060.1 - 0.0022 17.8 0.1 0.045 13.5 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Caps_synth_CapC PF14102.6 EIM84060.1 - 0.22 11.9 9.9 0.58 10.6 9.9 1.7 1 0 0 1 1 1 0 Capsule biosynthesis CapC XendoU PF09412.10 EIM84062.1 - 0.17 11.0 0.1 0.25 10.5 0.1 1.1 1 0 0 1 1 1 0 Endoribonuclease XendoU DUF4246 PF14033.6 EIM84063.1 - 1.2e-80 271.8 0.1 1.7e-80 271.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EIM84063.1 - 0.0077 16.6 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF4246 PF14033.6 EIM84066.1 - 6.6e-187 622.1 0.0 7.8e-187 621.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EIM84066.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase BOFC_N PF08977.10 EIM84066.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Pkinase PF00069.25 EIM84067.1 - 8.8e-59 199.0 0.0 1.7e-32 112.8 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 EIM84067.1 - 1.6e-44 152.4 7.3 8.1e-43 146.8 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 EIM84067.1 - 1.3e-29 103.3 0.0 5.6e-15 55.3 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EIM84067.1 - 1.9e-11 44.2 1.2 3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EIM84067.1 - 1.1e-06 28.2 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.23 EIM84067.1 - 0.0018 18.2 1.3 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM84067.1 - 0.031 13.1 0.1 0.031 13.1 0.1 2.5 3 0 0 3 3 3 0 Fungal protein kinase Kinase-like PF14531.6 EIM84067.1 - 0.04 13.2 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF2102 PF09875.9 EIM84067.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) FTA2 PF13095.6 EIM84067.1 - 0.077 12.6 0.0 2 8.0 0.0 2.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GST_N_2 PF13409.6 EIM84068.1 - 1.3e-20 73.5 0.0 2.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM84068.1 - 1.8e-13 50.3 0.0 3.9e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM84068.1 - 1e-07 32.1 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM84068.1 - 2.2e-05 24.6 0.0 6.4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIM84068.1 - 0.0028 18.1 0.0 0.022 15.2 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YCII PF03795.14 EIM84069.1 - 4.8e-08 33.3 0.0 5.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF2749 PF10907.8 EIM84069.1 - 0.098 12.8 0.1 6 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Glyco_hydro_10 PF00331.20 EIM84070.1 - 6.2e-98 327.8 0.0 7.5e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4998 PF16389.5 EIM84070.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DNase_NucA_NucB PF14040.6 EIM84071.1 - 1.4e-15 57.7 2.7 4e-14 53.0 0.6 2.9 2 1 0 2 2 2 1 Deoxyribonuclease NucA/NucB DUF4246 PF14033.6 EIM84073.1 - 7.6e-184 612.0 0.0 8.9e-184 611.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EIM84073.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase p450 PF00067.22 EIM84075.1 - 4.6e-62 210.3 0.0 5.3e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84076.1 - 5.5e-59 200.1 0.0 7e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84077.1 - 2.2e-29 102.5 0.0 2.6e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84078.1 - 2.5e-21 76.0 0.0 2.7e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84079.1 - 2.3e-51 175.0 0.0 3e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84080.1 - 6.2e-60 203.3 0.0 8.5e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MrpF_PhaF PF04066.13 EIM84080.1 - 0.17 12.3 0.8 0.89 10.0 0.0 2.4 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) p450 PF00067.22 EIM84081.1 - 2e-60 204.9 0.0 2.5e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5549 PF17703.1 EIM84082.1 - 0.04 13.6 1.8 0.059 13.0 1.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) DUF2062 PF09835.9 EIM84082.1 - 0.34 10.8 2.2 0.5 10.2 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Ribosomal_S7 PF00177.21 EIM84083.1 - 1.1e-22 80.3 0.6 1.3e-22 80.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e YtpI PF14007.6 EIM84085.1 - 0.053 13.7 1.7 0.06 13.5 0.2 1.9 2 0 0 2 2 2 0 YtpI-like protein Glyco_hydro_10 PF00331.20 EIM84086.1 - 9.2e-92 307.6 0.0 1e-91 307.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase PF00150.18 EIM84086.1 - 0.0091 15.5 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Alpha-amylase PF00128.24 EIM84087.1 - 6e-14 52.3 0.0 8.9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EIM84087.1 - 4.3e-09 36.7 0.0 9.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Sugar_tr PF00083.24 EIM84088.1 - 1e-110 370.8 16.1 1.2e-110 370.5 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM84088.1 - 4.1e-17 62.2 36.4 1.4e-13 50.5 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EIM84088.1 - 0.00019 20.5 0.4 0.00019 20.5 0.4 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Phage_holin_3_2 PF04550.12 EIM84088.1 - 0.021 15.3 1.1 0.061 13.9 1.1 1.8 1 0 0 1 1 1 0 Phage holin family 2 RNase_H PF00075.24 EIM84089.1 - 3.7e-28 98.5 0.0 6.1e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 EIM84089.1 - 6.7e-08 33.2 0.2 1.7e-07 31.8 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 EIM84090.1 - 3.1e-07 30.1 0.0 4.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HetR_C PF18460.1 EIM84090.1 - 0.0033 17.3 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Heterocyst differentiation regulator C-terminal Hood domain TFIIA PF03153.13 EIM84091.1 - 0.086 12.8 19.9 0.11 12.4 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 EIM84091.1 - 1.5 8.7 5.9 1.8 8.4 5.9 1.2 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 EIM84091.1 - 5.1 6.6 19.4 7.7 6.1 19.4 1.2 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 EIM84091.1 - 7.3 5.1 11.3 9.8 4.7 11.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1857 PF08982.11 EIM84092.1 - 4.4e-35 120.7 0.0 4.9e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Crystall_2 PF09076.10 EIM84092.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 2 0 0 2 2 2 0 Beta/Gamma crystallin Cu-oxidase PF00394.22 EIM84093.1 - 1.2e-49 168.5 0.1 1.9e-44 151.6 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM84093.1 - 1e-37 129.0 6.7 1.2e-35 122.3 0.3 4.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM84093.1 - 2.8e-37 127.4 2.1 1.7e-36 124.8 0.7 2.7 2 0 0 2 2 2 1 Multicopper oxidase RRM PF10378.9 EIM84093.1 - 0.35 10.6 2.4 0.78 9.5 2.4 1.5 1 0 0 1 1 1 0 Putative RRM domain NAD_binding_10 PF13460.6 EIM84094.1 - 1.4e-16 60.9 0.1 1.4e-15 57.7 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM84094.1 - 1.3e-08 34.6 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EIM84094.1 - 2.1e-07 30.8 0.1 2.8e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM84094.1 - 1.3e-05 24.8 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EIM84094.1 - 0.0014 18.7 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 EIM84094.1 - 0.0064 16.0 0.1 0.0089 15.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EIM84094.1 - 0.024 13.7 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIM84094.1 - 0.059 12.5 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EIM84094.1 - 0.099 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HEAT_2 PF13646.6 EIM84094.1 - 0.18 12.3 0.2 1.2 9.5 0.0 2.3 3 0 0 3 3 3 0 HEAT repeats DUF1857 PF08982.11 EIM84096.1 - 2.2e-34 118.4 0.0 2.5e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Mucin-like PF16058.5 EIM84097.1 - 8.6e-05 22.6 11.5 8.6e-05 22.6 11.5 7.4 5 3 2 7 7 7 2 Mucin-like 4HBT PF03061.22 EIM84098.1 - 1e-07 32.2 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Alpha-amylase_C PF02806.18 EIM84100.1 - 6.3e-12 45.8 0.1 1.6e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EIM84100.1 - 1.6e-11 44.4 0.1 2.3e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Thaumatin PF00314.17 EIM84101.1 - 5e-71 238.7 13.4 5.6e-71 238.6 13.4 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EIM84101.1 - 0.00097 18.5 0.1 0.00097 18.5 0.1 1.8 2 0 0 2 2 2 1 Beta-1,3-glucanase Pro_isomerase PF00160.21 EIM84105.1 - 1e-42 146.1 0.0 1.1e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Xpo1 PF08389.12 EIM84107.1 - 0.042 13.9 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Exportin 1-like protein SRAP PF02586.14 EIM84108.1 - 2.4e-34 118.8 0.0 3.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) LepA_C PF06421.12 EIM84108.1 - 0.22 11.7 0.3 0.9 9.7 0.1 1.9 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus SRAP PF02586.14 EIM84109.1 - 1.1e-21 77.5 0.0 4.2e-17 62.4 0.0 2.3 1 1 1 2 2 2 2 SOS response associated peptidase (SRAP) SSP160 PF06933.11 EIM84109.1 - 0.19 9.9 11.4 0.24 9.5 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SOG2 PF10428.9 EIM84109.1 - 1.3 8.2 20.5 1.7 7.7 20.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein F-box-like PF12937.7 EIM84110.1 - 1.5e-07 31.2 0.1 9.2e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 F-box-like DnaJ PF00226.31 EIM84111.1 - 1.5e-13 50.6 0.7 4.4e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain DnaJ_C PF01556.18 EIM84111.1 - 0.00018 21.7 0.0 0.00055 20.1 0.0 1.7 1 1 0 1 1 1 1 DnaJ C terminal domain Glyco_hydro_18 PF00704.28 EIM84114.1 - 5.2e-12 46.1 0.8 9.6e-12 45.2 0.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 EIM84114.1 - 0.00099 19.6 1.8 0.00099 19.6 1.8 3.6 4 0 0 4 4 4 1 Carbohydrate binding domain ERCC4 PF02732.15 EIM84115.1 - 2.3e-19 70.1 0.0 4.1e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain AAA PF00004.29 EIM84116.1 - 4.3e-17 62.8 0.0 9.2e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM84116.1 - 0.00021 21.3 0.2 0.0011 19.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM84116.1 - 0.00023 21.4 1.8 0.0082 16.4 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EIM84116.1 - 0.0012 19.2 0.1 0.0023 18.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EIM84116.1 - 0.0028 17.5 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM84116.1 - 0.0037 17.0 0.4 0.011 15.5 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM84116.1 - 0.026 14.9 0.0 0.076 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EIM84116.1 - 0.067 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EIM84116.1 - 0.069 12.5 0.7 0.23 10.8 0.2 2.0 1 1 2 3 3 3 0 Magnesium chelatase, subunit ChlI Vps36_ESCRT-II PF11605.8 EIM84116.1 - 0.09 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_6 PF12774.7 EIM84116.1 - 0.098 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Viral_RdRp_C PF17501.2 EIM84117.1 - 1.6 9.2 4.2 1.1 9.7 1.9 1.8 2 0 0 2 2 2 0 Viral RNA-directed RNA polymerase Git3 PF11710.8 EIM84117.1 - 4 7.1 14.1 15 5.3 12.8 2.3 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 RCC1 PF00415.18 EIM84118.1 - 4.1e-40 136.2 6.8 2.5e-09 37.6 0.0 7.7 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIM84118.1 - 5.7e-20 70.6 29.0 9e-09 34.9 0.8 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat UPF0114 PF03350.16 EIM84119.1 - 2.3 8.5 7.3 0.14 12.4 0.6 2.3 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 Ribosomal_L7Ae PF01248.26 EIM84120.1 - 3.8e-21 74.6 1.0 7.4e-21 73.7 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Efg1 PF10153.9 EIM84120.1 - 0.096 13.1 4.7 0.23 11.9 0.8 2.4 2 0 0 2 2 2 0 rRNA-processing protein Efg1 CLPTM1 PF05602.12 EIM84120.1 - 0.19 10.7 0.2 0.27 10.2 0.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MFS_1 PF07690.16 EIM84122.1 - 2.5e-42 145.1 25.0 2.5e-42 145.1 25.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM84122.1 - 1.3e-16 60.5 5.3 1.3e-16 60.5 5.3 1.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EIM84122.1 - 6.8e-05 21.5 3.2 6.8e-05 21.5 3.2 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF389 PF04087.14 EIM84122.1 - 0.044 13.8 0.0 0.044 13.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF389) OATP PF03137.20 EIM84122.1 - 0.18 10.0 2.5 0.45 8.7 0.2 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 EIM84123.1 - 2.9e-23 82.4 0.0 4.1e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84123.1 - 8.8e-17 61.4 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EIM84123.1 - 3e-09 37.1 0.3 5.5e-09 36.2 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM84123.1 - 5.1e-05 23.3 0.1 9.1e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM84123.1 - 0.00039 20.0 0.3 0.0037 16.8 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EIM84123.1 - 0.00057 19.5 0.2 0.00096 18.8 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM84123.1 - 0.003 17.0 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EIM84123.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.22 EIM84124.1 - 2.1e-58 198.2 0.0 3e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.25 EIM84125.1 - 4.7e-34 116.5 4.0 9.7e-12 45.1 0.0 3.5 3 0 0 3 3 3 3 Phosphopantetheine attachment site PS-DH PF14765.6 EIM84125.1 - 2e-22 79.8 0.1 3e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 EIM84125.1 - 4.3e-16 59.7 0.1 5.5e-15 56.1 0.1 2.6 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 EIM84125.1 - 0.0022 18.6 0.4 0.0022 18.6 0.4 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 EIM84126.1 - 1.8e-50 171.8 0.0 2e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ketoacyl-synt PF00109.26 EIM84127.1 - 8.8e-78 261.4 0.0 2.4e-77 259.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EIM84127.1 - 5.2e-46 157.6 0.0 8.8e-44 150.3 0.0 3.1 3 0 0 3 3 3 1 Acyl transferase domain PP-binding PF00550.25 EIM84127.1 - 1.2e-38 131.3 4.6 3.7e-13 49.6 0.0 4.9 5 0 0 5 5 5 3 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 EIM84127.1 - 4e-37 126.8 0.1 1.3e-36 125.1 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EIM84127.1 - 2.7e-27 95.8 0.0 4.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 EIM84127.1 - 9.7e-26 91.0 13.1 1.4e-25 90.5 3.0 3.5 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 EIM84127.1 - 3.8e-18 66.5 0.0 4e-17 63.1 0.0 2.7 4 0 0 4 4 4 1 Thioesterase domain KAsynt_C_assoc PF16197.5 EIM84127.1 - 6.3e-06 26.6 0.0 2e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EIM84127.1 - 0.00059 19.3 2.2 0.0015 17.9 0.0 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EIM84127.1 - 0.00079 20.1 8.9 0.0011 19.6 0.1 3.5 2 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM84127.1 - 0.043 13.5 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold GMC_oxred_N PF00732.19 EIM84128.1 - 5.7e-66 222.9 0.0 7.3e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84128.1 - 1.5e-30 106.6 0.1 2.4e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EIM84128.1 - 0.00038 19.8 0.0 0.0066 15.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM84128.1 - 0.0081 16.4 1.5 0.019 15.2 1.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM84128.1 - 0.0092 15.1 0.2 0.013 14.5 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM84128.1 - 0.027 13.6 1.2 1.4 7.9 1.2 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EIM84128.1 - 0.062 12.5 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 EIM84128.1 - 0.2 11.3 0.3 0.38 10.4 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 EIM84129.1 - 1.2e-30 106.4 0.0 4.3e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84129.1 - 7.5e-20 71.5 0.0 1.8e-14 53.9 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM84129.1 - 2.7e-09 37.2 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM84129.1 - 8.1e-05 22.2 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM84129.1 - 0.0033 16.9 0.0 0.009 15.4 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIM84129.1 - 0.0046 16.1 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CutC PF03932.14 EIM84129.1 - 0.022 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 CutC family UbiA PF01040.18 EIM84130.1 - 4.7e-40 137.5 14.1 1.4e-39 135.9 14.1 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family Polyketide_cyc2 PF10604.9 EIM84131.1 - 4.2e-08 33.6 0.1 6.8e-08 32.9 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EIM84131.1 - 3.2e-06 27.4 0.1 4.5e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 EIM84131.1 - 0.023 14.4 0.1 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) AHSA1 PF08327.11 EIM84131.1 - 0.075 13.3 0.6 0.24 11.7 0.6 1.7 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein AMP-binding PF00501.28 EIM84132.1 - 1.7e-29 102.7 0.2 4.4e-29 101.3 0.2 1.6 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EIM84132.1 - 4.2e-23 81.8 0.0 6.8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EIM84132.1 - 7e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM84132.1 - 9.4e-05 22.7 0.0 0.00024 21.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 EIM84132.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 EIM84133.1 - 2.4e-67 227.7 0.0 2.7e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84134.1 - 6.9e-58 196.5 0.0 1.2e-56 192.4 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EIM84135.1 - 2.2e-16 60.0 0.0 3.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM84135.1 - 0.0067 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM84135.1 - 0.0077 16.2 2.8 1.8 8.5 1.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EIM84135.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EIM84135.1 - 0.024 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EIM84135.1 - 0.061 12.7 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 EIM84136.1 - 4.2e-61 207.1 0.0 5.4e-60 203.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 RPW8 PF05659.11 EIM84140.1 - 0.16 11.7 1.7 0.78 9.4 0.6 2.1 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RPW8 PF05659.11 EIM84141.1 - 0.24 11.1 9.8 1.4 8.6 3.9 2.5 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF917 PF06032.12 EIM84142.1 - 4e-97 325.2 0.2 4e-97 325.2 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EIM84142.1 - 0.00028 20.2 8.3 0.0013 18.0 0.5 2.7 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase CheD PF03975.13 EIM84142.1 - 0.61 10.2 2.1 5.8 7.1 0.1 2.7 3 0 0 3 3 3 0 CheD chemotactic sensory transduction Alpha_GJ PF03229.13 EIM84142.1 - 3.2 8.3 6.6 7.7 7.1 6.6 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J EF-G-binding_N PF07299.11 EIM84144.1 - 0.057 14.0 0.0 0.098 13.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Plavaka PF18759.1 EIM84147.1 - 2.1e-111 372.3 0.0 2.8e-111 371.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Utp14 PF04615.13 EIM84149.1 - 3.1 6.2 25.8 0.044 12.4 17.0 1.9 2 0 0 2 2 2 0 Utp14 protein Nop14 PF04147.12 EIM84149.1 - 4.8 5.3 9.2 7.2 4.7 9.2 1.3 1 0 0 1 1 1 0 Nop14-like family OTT_1508_deam PF14441.6 EIM84150.1 - 5.1e-08 32.8 0.1 1.1e-07 31.8 0.1 1.6 1 1 0 1 1 1 1 OTT_1508-like deaminase DUF917 PF06032.12 EIM84151.1 - 1.9e-105 352.6 0.3 1.9e-105 352.6 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EIM84151.1 - 7.2e-31 107.3 0.1 9e-30 103.7 0.0 2.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EIM84151.1 - 2.1e-21 76.5 11.7 1.1e-20 74.1 5.3 3.6 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase MutL PF13941.6 EIM84151.1 - 0.00013 20.8 2.3 0.089 11.4 0.2 2.9 3 0 0 3 3 3 2 MutL protein StbA PF06406.11 EIM84151.1 - 0.0053 16.0 0.1 1.5 8.0 0.0 2.7 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 EIM84151.1 - 0.039 13.4 0.1 0.039 13.4 0.1 3.1 4 0 0 4 4 4 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 EIM84151.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain CheD PF03975.13 EIM84151.1 - 0.53 10.4 4.2 11 6.2 0.1 3.7 3 0 0 3 3 3 0 CheD chemotactic sensory transduction DIOX_N PF14226.6 EIM84154.1 - 4.4e-26 92.0 0.0 1e-25 90.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM84154.1 - 5.9e-17 62.0 0.0 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HpcH_HpaI PF03328.14 EIM84154.1 - 0.25 10.5 0.0 0.56 9.3 0.0 1.5 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Transp_cyt_pur PF02133.15 EIM84155.1 - 2.5e-84 283.6 33.3 3.2e-84 283.2 33.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-MYND PF01753.18 EIM84156.1 - 1.2e-09 38.1 12.2 3.2e-09 36.7 12.2 1.8 1 1 0 1 1 1 1 MYND finger DUF3039 PF11238.8 EIM84156.1 - 0.13 12.0 4.5 0.32 10.8 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-C6H2 PF15801.5 EIM84156.1 - 0.22 11.8 8.8 0.47 10.8 8.8 1.6 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Glyco_hydro_18 PF00704.28 EIM84159.1 - 1.6e-13 51.1 0.4 3.3e-13 50.0 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 EIM84159.1 - 0.0028 18.1 6.9 0.0028 18.1 6.9 3.6 3 1 0 3 3 3 1 Carbohydrate binding domain Amnionless PF14828.6 EIM84160.1 - 0.043 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4065 PF13274.6 EIM84161.1 - 0.075 13.9 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Aminotran_1_2 PF00155.21 EIM84162.1 - 9.6e-11 41.4 0.0 1.3e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Peptidase_C14 PF00656.22 EIM84163.1 - 6.3e-08 32.9 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Caspase domain PHD_4 PF16866.5 EIM84165.1 - 9.3e-05 22.4 6.1 9.3e-05 22.4 6.1 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EIM84165.1 - 0.00026 20.8 6.7 0.00026 20.8 6.7 2.3 2 1 0 2 2 2 1 PHD-finger C1_1 PF00130.22 EIM84165.1 - 0.0037 17.1 0.9 0.012 15.5 0.9 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EIM84165.1 - 0.0041 17.2 1.1 0.013 15.6 1.1 1.8 1 0 0 1 1 1 1 KIAA1045 RING finger Corona_nucleoca PF00937.18 EIM84165.1 - 0.0051 15.9 0.1 0.033 13.2 0.4 2.1 3 0 0 3 3 3 1 Coronavirus nucleocapsid protein NUDIX PF00293.28 EIM84166.1 - 3.3e-07 30.4 0.7 1.3e-06 28.5 0.7 1.9 1 1 0 1 1 1 1 NUDIX domain GrpE PF01025.19 EIM84166.1 - 0.11 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 GrpE adh_short PF00106.25 EIM84167.1 - 1.6e-18 66.9 0.0 6.2e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84167.1 - 2.1e-09 37.3 0.1 2.3e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM84167.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Dor1 PF04124.12 EIM84168.1 - 1.7e-48 165.1 0.0 7.8e-47 159.6 0.0 2.7 1 1 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 EIM84168.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Vps51/Vps67 COG2 PF06148.11 EIM84168.1 - 0.079 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 EIM84168.1 - 0.46 11.1 2.4 3.6 8.2 2.3 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF863 PF05904.11 EIM84168.1 - 4.5 5.6 9.3 6.3 5.1 9.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Gly-zipper_Omp PF13488.6 EIM84169.1 - 0.00088 19.2 0.8 0.0013 18.7 0.8 1.2 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EIM84169.1 - 0.049 13.4 0.4 0.084 12.6 0.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF3669 PF12417.8 EIM84169.1 - 0.16 12.2 0.2 0.3 11.3 0.2 1.4 1 0 0 1 1 1 0 Zinc finger protein DHR10 PF18595.1 EIM84170.1 - 0.023 14.7 0.4 0.04 14.0 0.4 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF5446 PF17522.2 EIM84170.1 - 0.024 14.8 0.2 0.047 13.8 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Get5_bdg PF16843.5 EIM84170.1 - 0.18 11.3 0.5 3.3 7.3 0.0 2.5 3 0 0 3 3 3 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Glyco_hydro_7 PF00840.20 EIM84171.1 - 1e-201 670.4 14.1 1.6e-201 669.7 14.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EIM84171.1 - 2.6e-12 46.4 14.5 2.6e-12 46.4 14.5 4.9 4 2 0 4 4 4 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.16 EIM84172.1 - 2.4e-32 112.7 13.3 3.4e-32 112.2 13.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CBM_1 PF00734.18 EIM84172.1 - 2.5e-13 49.7 13.3 2.5e-13 49.7 13.3 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.16 EIM84173.1 - 7.6e-31 107.8 11.0 7.6e-31 107.8 11.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 CBM_1 PF00734.18 EIM84173.1 - 9.4e-14 51.1 9.8 9.4e-14 51.1 9.8 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.16 EIM84174.1 - 2.9e-28 99.3 10.7 3.6e-28 99.0 10.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CDH-cyt PF16010.5 EIM84175.1 - 3.5e-60 202.8 1.7 4e-60 202.6 0.5 1.8 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EIM84175.1 - 1.4e-19 70.6 0.0 2.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84175.1 - 2.5e-19 70.2 0.3 9e-19 68.4 0.3 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM84175.1 - 6.8e-07 28.7 0.0 2.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EIM84175.1 - 3.6e-05 23.3 0.1 8.5e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM84175.1 - 0.00016 21.0 0.4 0.014 14.7 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM84175.1 - 0.00035 19.4 0.1 0.00056 18.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EIM84175.1 - 0.00044 20.4 0.4 0.0013 18.9 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIM84175.1 - 0.0013 18.0 0.1 0.0022 17.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM84175.1 - 0.0018 17.6 0.1 0.0036 16.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM84175.1 - 0.04 13.1 0.3 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EIM84175.1 - 0.22 10.6 0.3 0.49 9.4 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A AA_permease_2 PF13520.6 EIM84176.1 - 8.5e-63 212.6 29.8 9.9e-63 212.4 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3522 PF12036.8 EIM84176.1 - 0.02 15.2 3.2 0.02 15.2 3.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) GPHR_N PF12537.8 EIM84176.1 - 0.091 12.9 0.1 0.32 11.1 0.1 1.9 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal zf-C2HC_2 PF13913.6 EIM84177.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf_C2HC_14 PF18574.1 EIM84177.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.4 3 0 0 3 3 3 0 C2HC Zing finger domain zf-C2H2_4 PF13894.6 EIM84177.1 - 1.6 9.8 0.1 1.6 9.8 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger MULE PF10551.9 EIM84178.1 - 1e-05 25.8 0.3 3.8e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 EIM84178.1 - 0.046 13.4 0.3 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 SWIM zinc finger Gemini_AL3 PF01407.17 EIM84181.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Geminivirus AL3 protein Rap_GAP PF02145.15 EIM84183.1 - 3.4e-45 153.9 0.0 5e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EIM84183.1 - 1.7e-37 129.4 0.3 6.9e-36 124.1 0.1 2.3 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 EIM84183.1 - 4.9e-09 35.6 0.0 4.6e-07 29.1 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3384) GEN1_C PF18380.1 EIM84184.1 - 3.3e-26 92.2 0.2 3.3e-26 92.2 0.2 3.1 3 1 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EIM84184.1 - 4.1e-19 68.7 0.0 8.9e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EIM84184.1 - 0.0011 19.4 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Red1 PF07964.11 EIM84184.1 - 0.16 10.2 10.4 0.28 9.4 10.4 1.3 1 0 0 1 1 1 0 Rec10 / Red1 PBP1_TM PF14812.6 EIM84184.1 - 0.4 11.1 6.2 0.25 11.7 1.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSP70 PF00012.20 EIM84185.1 - 9.3e-263 872.9 4.8 1.1e-262 872.7 4.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIM84185.1 - 5.1e-17 61.7 0.6 3.1e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EIM84185.1 - 0.0057 15.7 0.6 0.062 12.3 0.3 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain RGS12_us2 PF16611.5 EIM84185.1 - 0.093 13.2 0.5 0.31 11.5 0.5 1.9 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco Hydantoinase_A PF01968.18 EIM84185.1 - 0.3 10.3 2.9 0.19 10.9 0.3 2.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Spectrin PF00435.21 EIM84185.1 - 1.3 9.5 8.6 9.3 6.8 0.6 3.2 2 1 0 3 3 3 0 Spectrin repeat FtsA PF14450.6 EIM84185.1 - 4.6 7.7 5.2 36 4.9 0.3 3.3 3 2 0 3 3 3 0 Cell division protein FtsA DUF89 PF01937.19 EIM84187.1 - 1.8e-107 359.4 0.0 2.2e-107 359.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Acetyltransf_1 PF00583.25 EIM84188.1 - 3e-16 59.7 0.0 4.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM84188.1 - 2.1e-09 37.7 0.0 3.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM84188.1 - 8.2e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM84188.1 - 3.5e-07 30.1 0.1 6.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EIM84188.1 - 1.1e-05 26.1 0.0 1.8e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EIM84188.1 - 2.1e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM84188.1 - 0.00011 22.2 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EIM84188.1 - 0.00075 19.7 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM84188.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 EIM84188.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.7 EIM84189.1 - 4.8e-07 29.6 0.2 1.5e-06 28.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like RCC1 PF00415.18 EIM84191.1 - 5.4e-58 193.4 17.0 3.3e-09 37.2 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIM84191.1 - 5.2e-32 109.0 42.7 1.9e-08 33.8 0.6 7.3 8 1 1 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EIM84191.1 - 0.0074 16.8 0.1 8.6 6.8 0.0 3.3 4 0 0 4 4 4 2 SUKH-3 immunity protein Hira PF07569.11 EIM84191.1 - 0.036 13.8 0.0 4 7.1 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split COesterase PF00135.28 EIM84192.1 - 3.2e-83 280.3 0.0 3.8e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM84192.1 - 9.1e-05 22.4 2.3 0.0009 19.2 2.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM84192.1 - 0.023 13.6 0.0 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase MFS_1 PF07690.16 EIM84193.1 - 1.1e-27 96.9 32.5 1.4e-27 96.6 31.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 EIM84193.1 - 0.0027 17.9 0.3 0.016 15.4 0.3 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) DUF1656 PF07869.12 EIM84193.1 - 0.37 10.8 0.1 0.37 10.8 0.1 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1656) MFS_1 PF07690.16 EIM84194.1 - 1.4e-30 106.4 28.7 1.4e-30 106.4 28.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 EIM84194.1 - 0.0019 18.4 0.7 0.0019 18.4 0.7 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2530) NST1 PF13945.6 EIM84195.1 - 2.8e-53 180.9 42.6 4e-53 180.4 9.5 5.4 3 2 2 5 5 5 3 Salt tolerance down-regulator CDC27 PF09507.10 EIM84195.1 - 0.003 17.0 27.9 0.003 17.0 27.9 4.1 2 1 2 4 4 4 1 DNA polymerase subunit Cdc27 PhoLip_ATPase_C PF16212.5 EIM84196.1 - 8.1e-53 179.7 24.7 8.1e-53 179.7 24.7 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIM84196.1 - 5.5e-17 61.2 4.0 1.3e-16 60.0 4.0 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EIM84196.1 - 3.7e-14 53.5 0.9 3.5e-08 34.0 0.7 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EIM84196.1 - 6.4e-14 51.9 0.0 6.4e-14 51.9 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EIM84196.1 - 8e-08 32.3 0.0 2.2e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EIM84196.1 - 3.4e-05 23.7 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Choline_kin_N PF04428.14 EIM84196.1 - 0.1 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Choline kinase N terminus zinc_ribbon_12 PF11331.8 EIM84197.1 - 0.079 12.8 1.3 0.48 10.3 0.3 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain Ribosomal_L12 PF00542.19 EIM84197.1 - 0.081 13.3 4.7 0.26 11.7 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Syntaxin-6_N PF09177.11 EIM84197.1 - 0.17 12.5 1.2 0.33 11.5 0.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal zf_UBZ PF18439.1 EIM84197.1 - 0.21 11.2 1.6 1 9.0 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger MqsA_antitoxin PF15731.5 EIM84197.1 - 0.33 11.1 1.6 3.3 7.8 0.0 3.1 4 0 0 4 4 4 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA SIKE PF05769.11 EIM84197.1 - 2.7 7.9 7.7 2.7 7.9 0.1 2.5 3 0 0 3 3 3 0 SIKE family LsmAD PF06741.13 EIM84197.1 - 3.5 8.2 6.0 8.6 7.0 6.0 1.6 1 0 0 1 1 1 0 LsmAD domain DUF2093 PF09866.9 EIM84199.1 - 0.061 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) F-box-like PF12937.7 EIM84200.1 - 3.4e-12 46.1 0.6 7.8e-12 44.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 EIM84202.1 - 7.3e-93 311.9 18.4 8.5e-93 311.7 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM84202.1 - 1.1e-25 90.4 40.3 1.3e-13 50.7 17.8 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM84202.1 - 0.0081 14.6 3.7 0.016 13.7 3.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.19 EIM84202.1 - 0.043 14.1 0.4 0.043 14.1 0.4 3.4 4 1 0 4 4 4 0 Uncharacterized protein family UPF0016 OATP PF03137.20 EIM84202.1 - 1.6 6.9 10.8 0.55 8.4 0.1 2.8 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family GATA PF00320.27 EIM84204.1 - 3.3e-25 87.4 19.1 4.8e-15 54.9 2.9 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 EIM84204.1 - 2.5e-11 43.2 0.3 6.5e-11 41.9 0.3 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 EIM84204.1 - 0.018 15.2 5.7 1.1 9.4 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 EIM84204.1 - 0.085 13.1 1.2 0.18 12.1 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon OTT_1508_deam PF14441.6 EIM84204.1 - 0.16 12.0 1.1 8.7 6.4 0.0 2.7 2 0 0 2 2 2 0 OTT_1508-like deaminase zinc_ribbon_4 PF13717.6 EIM84204.1 - 0.19 11.7 3.3 1.5 8.8 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EIM84204.1 - 0.2 11.9 6.0 0.83 9.9 0.9 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 EIM84204.1 - 0.5 10.3 6.4 5.1 7.0 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EIM84204.1 - 0.51 9.9 7.9 0.32 10.5 1.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 EIM84204.1 - 3.1 7.8 9.2 2.5 8.1 2.1 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 EIM84204.1 - 4.8 6.9 8.7 0.11 12.2 0.7 2.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 EIM84204.1 - 6.5 6.9 10.7 61 3.8 10.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon CHZ PF09649.10 EIM84205.1 - 1.8e-14 52.9 0.2 1.8e-14 52.9 0.2 2.3 3 1 0 3 3 3 1 Histone chaperone domain CHZ zf-C2H2_4 PF13894.6 EIM84206.1 - 1.2e-20 72.4 25.3 0.01 16.6 0.6 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM84206.1 - 1e-12 48.0 24.6 0.0056 16.9 0.7 6.8 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EIM84206.1 - 8.4e-10 38.6 31.5 0.22 12.0 1.5 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EIM84206.1 - 4.7e-09 36.5 18.6 0.0013 19.0 1.5 5.6 2 2 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EIM84206.1 - 3.4e-08 33.6 23.6 0.69 10.4 0.2 6.8 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EIM84206.1 - 3.7e-05 23.6 25.8 0.032 14.2 0.8 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 EIM84206.1 - 0.0003 20.6 7.6 4.9 7.1 0.2 4.4 3 1 1 4 4 4 2 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 EIM84206.1 - 0.0016 18.8 3.0 0.034 14.6 0.2 6.4 7 0 0 7 7 6 2 Zinc-finger double domain zf-C2H2_9 PF16293.5 EIM84206.1 - 0.0082 16.0 14.1 1.5 8.7 0.4 5.8 3 2 3 6 6 6 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 EIM84206.1 - 0.068 13.5 21.5 0.2 11.9 1.9 4.8 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Mob_synth_C PF06463.13 EIM84206.1 - 0.16 11.9 6.1 0.3 11.0 0.1 3.2 1 1 2 3 3 3 0 Molybdenum Cofactor Synthesis C zf-C2HC_2 PF13913.6 EIM84206.1 - 0.19 11.7 18.7 0.97 9.4 0.5 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 EIM84206.1 - 2.4 8.1 17.2 4.1 7.4 0.2 5.0 5 0 0 5 5 5 0 zinc-ribbon domain zf-RING_7 PF02591.15 EIM84206.1 - 3.5 7.9 12.5 9.5 6.5 0.1 4.8 5 0 0 5 5 5 0 C4-type zinc ribbon domain zf-C2H2_8 PF15909.5 EIM84206.1 - 3.7 7.9 18.2 3.4 8.0 0.3 4.5 3 2 2 5 5 5 0 C2H2-type zinc ribbon DUF1610 PF07754.11 EIM84206.1 - 7.2 6.7 8.9 7 6.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-C2HE PF16278.5 EIM84206.1 - 8.6 6.9 16.8 13 6.3 0.4 4.2 3 2 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger F-box-like PF12937.7 EIM84207.1 - 1.1e-05 25.2 0.4 3.3e-05 23.7 0.4 1.9 1 0 0 1 1 1 1 F-box-like AIRC PF00731.20 EIM84209.1 - 5.7e-61 204.4 1.6 1.4e-60 203.2 0.7 2.1 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 EIM84209.1 - 6.2e-58 195.2 0.0 9.6e-58 194.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EIM84209.1 - 3.4e-20 71.5 0.0 7.5e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EIM84209.1 - 1.8e-07 30.9 0.0 3.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EIM84209.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EIM84209.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain SPATIAL PF15256.6 EIM84209.1 - 0.095 13.0 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 SPATIAL ABA_GPCR PF12430.8 EIM84211.1 - 1.2e-29 103.4 0.0 1.2e-29 103.4 0.0 2.4 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EIM84211.1 - 1.8e-14 53.6 0.0 6e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal NAD_binding_10 PF13460.6 EIM84212.1 - 8.8e-22 77.9 0.0 1.1e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding MFS_1 PF07690.16 EIM84214.1 - 4.6e-35 121.2 48.9 8.3e-35 120.3 46.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM84214.1 - 6.3e-22 77.7 21.6 7.9e-22 77.4 21.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIM84214.1 - 9.6e-11 41.2 14.8 9.6e-11 41.2 14.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter HlyIII PF03006.20 EIM84214.1 - 0.017 14.9 1.0 0.017 14.9 1.0 3.2 2 1 0 3 3 3 0 Haemolysin-III related adh_short PF00106.25 EIM84215.1 - 4.3e-42 143.8 0.1 5.4e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84215.1 - 3.3e-28 98.9 0.0 4e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM84215.1 - 0.00037 20.4 0.5 0.00076 19.4 0.5 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM84215.1 - 0.00097 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EIM84215.1 - 0.0075 16.2 0.7 0.037 14.0 0.3 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DFP PF04127.15 EIM84215.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Acyl-CoA_dh_M PF02770.19 EIM84216.1 - 0.006 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EIM84216.1 - 0.0078 16.4 0.5 0.016 15.5 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 EIM84217.1 - 6.2e-67 226.3 0.0 9e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.14 EIM84218.1 - 9.7e-27 94.4 0.0 4.8e-26 92.1 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) F-box-like PF12937.7 EIM84221.1 - 0.03 14.2 4.2 0.12 12.3 4.2 2.2 1 0 0 1 1 1 0 F-box-like Kdo PF06293.14 EIM84222.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF1G PF00647.19 EIM84223.1 - 9.2e-44 147.9 0.0 1.5e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EIM84223.1 - 1.1e-10 41.6 1.9 1.2e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM84223.1 - 2.1e-07 30.9 0.0 5.5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM84223.1 - 0.00055 20.1 2.1 0.00057 20.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RNA_pol_Rpc4 PF05132.14 EIM84223.1 - 0.57 10.6 5.1 0.93 9.9 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 OAD_gamma PF04277.13 EIM84223.1 - 8.4 7.1 10.5 18 6.0 10.5 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-MYND PF01753.18 EIM84225.1 - 1.1e-09 38.2 29.2 2.1e-09 37.3 18.6 3.3 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 EIM84225.1 - 0.18 12.0 0.2 0.18 12.0 0.2 3.2 4 0 0 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 Acetyltransf_1 PF00583.25 EIM84227.1 - 2.2e-11 44.0 0.0 7.2e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM84227.1 - 2.7e-10 40.5 0.0 1e-08 35.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM84227.1 - 4.7e-09 36.2 0.0 2.2e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM84227.1 - 0.00068 19.7 0.0 0.091 12.8 0.0 2.9 1 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM84227.1 - 0.035 14.2 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase F-box-like PF12937.7 EIM84228.1 - 2.6e-07 30.4 0.5 9e-07 28.7 0.5 2.0 1 0 0 1 1 1 1 F-box-like RNA_pol_3_Rpc31 PF11705.8 EIM84228.1 - 0.0045 17.3 3.6 0.0069 16.7 3.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 F-box PF00646.33 EIM84228.1 - 0.056 13.3 0.4 0.2 11.6 0.4 2.1 1 0 0 1 1 1 0 F-box domain Glyco_hydro_72 PF03198.14 EIM84229.1 - 1.7e-103 346.2 0.0 2.1e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EIM84229.1 - 5.1e-20 71.9 1.4 1.3e-19 70.6 1.4 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EIM84229.1 - 0.00053 19.5 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TFIIA PF03153.13 EIM84232.1 - 5.1 7.0 29.4 0.16 12.0 23.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ACOX PF01756.19 EIM84235.1 - 3.7e-34 117.8 0.0 8.1e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EIM84235.1 - 5.8e-17 62.4 0.1 1.5e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EIM84235.1 - 1.1e-06 28.7 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EIM84235.1 - 0.0029 17.8 0.5 0.0077 16.4 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEC-1_C PF04626.13 EIM84236.1 - 0.003 18.0 0.1 0.0057 17.0 0.1 1.4 1 0 0 1 1 1 1 Dec-1 protein, C terminal region Fes1 PF08609.10 EIM84238.1 - 2.3e-24 86.1 0.3 1.3e-23 83.7 0.0 2.2 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Atx10homo_assoc PF09759.9 EIM84238.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain BCA_ABC_TP_C PF12399.8 EIM84238.1 - 0.034 14.1 0.8 0.061 13.3 0.1 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter HEAT_EZ PF13513.6 EIM84238.1 - 0.13 12.8 0.1 34 5.1 0.0 3.0 2 1 0 2 2 2 0 HEAT-like repeat NUDE_C PF04880.13 EIM84238.1 - 0.59 10.6 5.1 1.2 9.6 5.1 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Acyl-CoA_dh_M PF02770.19 EIM84239.1 - 9.9e-06 25.7 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF829 PF05705.14 EIM84240.1 - 5.8e-29 101.7 0.0 7.3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.16 EIM84241.1 - 5.5e-30 104.5 48.0 5.5e-30 104.5 48.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM84241.1 - 1.8e-23 82.9 20.6 2.1e-23 82.6 20.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIM84241.1 - 5.2e-13 48.7 10.8 5.2e-13 48.7 10.8 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter p450 PF00067.22 EIM84242.1 - 1.4e-32 113.1 0.0 4.4e-29 101.5 0.0 2.3 1 1 1 2 2 2 2 Cytochrome P450 CheR PF01739.18 EIM84242.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.22 EIM84244.1 - 6.3e-07 28.5 0.0 6.3e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84245.1 - 3.6e-49 167.8 0.0 4.4e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M24_C PF16188.5 EIM84247.1 - 0.054 13.6 0.1 2.9 8.0 0.0 2.7 2 1 0 2 2 2 0 C-terminal region of peptidase_M24 UbiA PF01040.18 EIM84248.1 - 1.3e-26 93.5 13.1 1.6e-26 93.2 13.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF21 PF01595.20 EIM84248.1 - 2.2 8.0 6.0 1.2 8.8 0.4 2.8 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain GST_N_3 PF13417.6 EIM84249.1 - 1.3e-18 67.2 0.0 4.1e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM84249.1 - 9.7e-18 64.2 0.0 2.2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM84249.1 - 6.6e-12 45.6 0.1 3.5e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM84249.1 - 1.3e-05 25.2 1.5 3.8e-05 23.6 0.0 2.3 2 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM84249.1 - 2.5e-05 24.4 0.1 7.6e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM84249.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EIM84249.1 - 0.028 15.0 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4441 PF14536.6 EIM84249.1 - 0.097 12.9 0.1 0.31 11.2 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) DUF1702 PF08012.11 EIM84249.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) FAD_binding_3 PF01494.19 EIM84251.1 - 8e-16 58.2 0.0 7.2e-09 35.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM84251.1 - 0.032 14.5 0.2 0.14 12.4 0.4 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.7 EIM84252.1 - 8.5e-05 22.4 0.9 0.00032 20.5 0.1 2.4 2 0 0 2 2 2 1 F-box-like Cullin_binding PF03556.15 EIM84253.1 - 6.2e-36 123.5 1.0 1e-35 122.8 1.0 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EIM84253.1 - 5.1e-06 26.2 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain F-box-like PF12937.7 EIM84254.1 - 2.2e-07 30.7 1.7 6.3e-07 29.2 1.7 1.9 1 0 0 1 1 1 1 F-box-like Importin_rep_6 PF18829.1 EIM84254.1 - 0.51 10.5 2.0 1.2 9.3 2.0 1.6 1 0 0 1 1 1 0 Importin repeat 6 GMC_oxred_N PF00732.19 EIM84255.1 - 5.4e-47 160.6 0.0 1.1e-28 100.5 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84255.1 - 3e-26 92.7 0.3 2.8e-21 76.5 0.1 2.3 1 1 1 2 2 2 2 GMC oxidoreductase Glyco_hydro_79C PF16862.5 EIM84257.1 - 4.6e-16 59.6 0.0 8.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain QIL1 PF15884.5 EIM84257.1 - 0.034 14.8 0.0 0.065 13.8 0.0 1.4 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 Med30 PF11315.8 EIM84258.1 - 0.0031 17.7 1.2 0.0069 16.6 1.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 30 Hc1 PF07432.13 EIM84258.1 - 0.21 12.0 0.7 0.37 11.2 0.7 1.3 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Pkinase PF00069.25 EIM84259.1 - 2.7e-06 26.9 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EIM84259.1 - 3.4e-05 23.3 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EIM84259.1 - 0.00012 21.7 0.1 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EIM84259.1 - 0.00022 20.6 0.0 0.00079 18.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM84259.1 - 0.0012 18.8 0.3 0.017 15.0 0.3 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM84259.1 - 0.0081 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase WaaY PF06176.11 EIM84259.1 - 0.022 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EIM84259.1 - 0.039 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PI3_PI4_kinase PF00454.27 EIM84259.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Kdo PF06293.14 EIM84260.1 - 0.0003 20.2 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EIM84260.1 - 0.0038 16.6 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3568 PF12092.8 EIM84260.1 - 0.22 11.6 0.0 0.34 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Spt5_N PF11942.8 EIM84260.1 - 1.1 10.2 9.9 2.2 9.3 9.9 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-MYND PF01753.18 EIM84262.1 - 7.6e-08 32.3 15.4 7.6e-08 32.3 15.4 2.1 2 0 0 2 2 2 1 MYND finger DsbB PF02600.16 EIM84263.1 - 0.00067 20.1 11.4 0.0042 17.5 0.8 4.1 5 1 0 5 5 5 2 Disulfide bond formation protein DsbB RepL PF05732.11 EIM84263.1 - 0.039 13.4 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) zf-RING_4 PF14570.6 EIM84264.1 - 0.15 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3446 PF11928.8 EIM84264.1 - 1.2 9.5 12.6 2.8 8.3 12.6 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Coatomer_g_Cpla PF16381.5 EIM84265.1 - 0.18 12.0 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform tRNA-synt_1 PF00133.22 EIM84266.1 - 1e-37 129.7 0.1 7.8e-28 97.1 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EIM84266.1 - 5.1e-15 55.1 0.0 1.9e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EIM84266.1 - 1.7e-14 54.1 0.8 6.4e-14 52.2 0.1 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EIM84266.1 - 5.5e-09 35.8 0.1 1.2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EIM84266.1 - 0.14 11.6 0.2 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Amidohydro_2 PF04909.14 EIM84267.1 - 8.1e-09 35.7 0.1 2.4e-06 27.5 0.0 2.0 1 1 1 2 2 2 2 Amidohydrolase F-box PF00646.33 EIM84268.1 - 1.5e-07 31.1 0.5 3.9e-07 29.8 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM84268.1 - 4.7e-07 29.6 0.2 1.3e-06 28.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-primase PF09329.11 EIM84269.1 - 1.7e-16 59.7 2.0 3.1e-16 58.9 2.0 1.5 1 0 0 1 1 1 1 Primase zinc finger Peptidase_C65 PF10275.9 EIM84270.1 - 9.2e-65 218.5 0.0 1.1e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EIM84270.1 - 0.0002 21.9 0.0 0.032 14.7 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease PseudoU_synth_1 PF01416.20 EIM84271.1 - 2.4e-21 76.2 0.0 5.8e-19 68.5 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase Oxysterol_BP PF01237.18 EIM84272.1 - 2.5e-64 217.4 2.3 4.5e-57 193.6 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein RNA_pol_Rpb2_6 PF00562.28 EIM84273.1 - 5.8e-122 407.5 0.4 7.8e-122 407.1 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EIM84273.1 - 3.1e-56 190.1 0.0 5.3e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EIM84273.1 - 3.6e-32 110.6 0.2 8.7e-32 109.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EIM84273.1 - 9e-28 97.2 0.0 4.1e-27 95.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EIM84273.1 - 1.8e-24 85.8 4.2 3.5e-24 84.8 2.7 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EIM84273.1 - 2.4e-20 72.5 0.0 5.4e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EIM84273.1 - 9.8e-11 42.1 1.3 3.2e-10 40.4 1.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ALO PF04030.14 EIM84274.1 - 5.8e-75 252.5 0.7 7.3e-75 252.1 0.7 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EIM84274.1 - 1.3e-27 96.2 0.7 2.1e-27 95.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain HSP70 PF00012.20 EIM84275.1 - 0.00044 18.6 0.0 0.0011 17.2 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein Noc2 PF03715.13 EIM84277.1 - 2.9e-115 384.6 0.0 1.5e-112 375.7 0.0 2.5 2 0 0 2 2 2 2 Noc2p family Arm-DNA-bind_3 PF13356.6 EIM84277.1 - 0.23 11.8 0.1 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain MT-A70 PF05063.14 EIM84278.1 - 1.8e-39 135.4 0.0 3.9e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 MT-A70 Selenoprotein_S PF06936.11 EIM84278.1 - 0.064 13.1 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) N6-adenineMlase PF10237.9 EIM84278.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase TPR_1 PF00515.28 EIM84279.1 - 2.1e-23 81.1 5.0 2.6e-06 27.0 0.0 7.1 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM84279.1 - 1.5e-22 77.8 12.2 4.3e-05 23.3 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.31 EIM84279.1 - 3.3e-18 65.6 0.3 2.1e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_9 PF13371.6 EIM84279.1 - 3e-16 59.3 14.0 1.7e-06 28.1 0.8 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EIM84279.1 - 1.5e-14 54.4 10.8 4.9e-05 23.9 0.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIM84279.1 - 1.1e-13 50.7 17.5 0.00066 20.3 0.1 7.0 3 3 4 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EIM84279.1 - 8.3e-13 47.5 1.8 0.0085 16.2 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM84279.1 - 9.7e-11 41.2 4.4 0.00097 18.8 0.7 5.5 5 2 1 6 6 6 3 TPR repeat TPR_19 PF14559.6 EIM84279.1 - 9.1e-10 38.9 10.8 0.0015 19.0 0.1 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM84279.1 - 4.8e-08 33.2 18.7 1.8e-06 28.1 1.7 5.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM84279.1 - 3.7e-05 24.1 3.1 0.0068 17.0 0.0 5.4 6 1 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM84279.1 - 0.00015 22.0 3.9 0.17 12.1 0.7 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EIM84279.1 - 0.0004 19.7 6.4 1.3 8.2 0.2 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM84279.1 - 0.0005 20.1 4.1 0.61 10.2 0.0 3.5 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EIM84279.1 - 0.0018 18.2 16.9 0.028 14.5 0.0 7.2 8 1 0 8 8 7 1 Tetratricopeptide repeat NARP1 PF12569.8 EIM84279.1 - 0.0038 16.2 0.2 1.1 8.1 0.0 2.7 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 EIM84279.1 - 0.012 16.0 9.3 4.9 7.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EIM84279.1 - 0.03 14.4 0.1 0.74 9.9 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF4398 PF14346.6 EIM84279.1 - 0.038 14.6 0.6 0.038 14.6 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) HrpB1_HrpK PF09613.10 EIM84279.1 - 0.063 12.9 4.8 0.57 9.8 0.3 3.2 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Alkyl_sulf_dimr PF14863.6 EIM84279.1 - 0.088 13.3 3.5 8.6 6.8 0.2 3.0 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation BTAD PF03704.17 EIM84279.1 - 0.36 11.3 11.5 4.8 7.6 1.1 4.8 2 1 2 4 4 4 0 Bacterial transcriptional activator domain DUF1840 PF08895.11 EIM84279.1 - 0.98 9.8 3.4 11 6.4 0.5 3.2 4 0 0 4 4 3 0 Domain of unknown function (DUF1840) DUF4192 PF13830.6 EIM84279.1 - 3.3 7.7 11.4 0.69 9.9 0.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) BAR PF03114.18 EIM84280.1 - 3.2e-38 131.7 16.0 5.3e-38 131.0 16.0 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EIM84280.1 - 1.5e-10 40.5 1.1 2.8e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EIM84280.1 - 4e-10 39.2 0.2 9.4e-10 38.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EIM84280.1 - 3.3e-08 33.3 0.1 7.7e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Fib_alpha PF08702.10 EIM84280.1 - 0.81 9.9 6.2 2.3 8.4 6.2 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SWIB PF02201.18 EIM84281.1 - 4.4e-20 71.3 0.0 9.2e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain SNF2_N PF00176.23 EIM84282.1 - 6.1e-36 123.9 0.0 8.1e-19 67.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM84282.1 - 7e-19 68.2 0.0 7.3e-17 61.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 EIM84282.1 - 0.00094 19.3 0.3 0.00094 19.3 0.3 2.8 1 1 1 2 2 2 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.15 EIM84282.1 - 0.007 16.4 0.1 3.8 7.5 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EIM84282.1 - 0.084 11.8 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 EIM84282.1 - 0.27 10.4 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase NOA36 PF06524.12 EIM84282.1 - 0.9 8.8 21.5 0.74 9.1 9.7 2.3 2 0 0 2 2 2 0 NOA36 protein TPR_2 PF07719.17 EIM84283.1 - 3.1e-22 76.9 8.8 0.022 14.9 0.0 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 EIM84283.1 - 2.7e-21 74.4 12.1 0.0041 16.9 0.1 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat DnaJ PF00226.31 EIM84283.1 - 6.1e-20 71.1 0.3 1.9e-19 69.6 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.6 EIM84283.1 - 1.5e-09 38.0 19.6 9.3e-06 25.9 0.5 6.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM84283.1 - 2e-09 36.9 11.0 0.57 10.5 0.1 7.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM84283.1 - 5.4e-09 35.6 7.4 0.11 12.2 0.6 6.4 6 0 0 6 6 6 2 TPR repeat TPR_16 PF13432.6 EIM84283.1 - 5.4e-06 27.0 14.9 0.057 14.1 0.1 6.0 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EIM84283.1 - 0.00013 22.1 11.4 1.4 9.1 0.0 5.6 4 3 2 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM84283.1 - 0.0011 19.4 13.2 2.8 8.5 0.7 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM84283.1 - 0.0025 18.5 13.7 12 7.0 0.0 7.2 6 3 3 9 9 8 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EIM84283.1 - 0.0029 17.6 0.6 0.78 9.8 0.0 3.4 2 2 1 3 3 3 1 Putative TPR-like repeat SHNi-TPR PF10516.9 EIM84283.1 - 0.0033 16.8 2.2 1.4 8.4 0.0 4.7 5 0 0 5 5 5 1 SHNi-TPR TPR_6 PF13174.6 EIM84283.1 - 0.0046 17.5 3.8 1.1 10.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIM84283.1 - 0.014 15.7 6.6 0.89 10.1 0.6 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM84283.1 - 0.038 14.0 17.2 1.3 9.3 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat MIT PF04212.18 EIM84283.1 - 0.04 14.0 15.1 0.34 11.0 0.1 5.7 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 EIM84283.1 - 0.078 13.1 6.4 0.24 11.5 0.2 3.8 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EIM84283.1 - 0.45 10.8 10.9 0.4 10.9 2.9 4.0 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCHC PF00098.23 EIM84284.1 - 4e-12 45.6 22.0 5.6e-05 23.0 0.4 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 EIM84284.1 - 0.0029 17.6 20.2 0.27 11.3 0.5 4.0 2 2 1 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 EIM84284.1 - 0.003 17.3 25.6 0.12 12.1 1.5 4.8 4 1 1 5 5 5 3 Zinc knuckle NinD PF17466.2 EIM84284.1 - 0.0042 17.1 3.3 0.0067 16.5 3.3 1.4 1 0 0 1 1 1 1 Family of unknown function zf-C2H2_10 PF16588.5 EIM84284.1 - 0.0046 16.7 11.0 0.045 13.5 1.7 3.7 2 1 1 3 3 3 2 C2H2 zinc-finger zf-CCHC_5 PF14787.6 EIM84284.1 - 0.023 14.4 13.9 0.74 9.6 4.1 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EIM84284.1 - 0.78 9.6 25.2 1.7 8.6 0.3 4.9 5 0 0 5 5 5 0 Zinc knuckle Saf_2TM PF18303.1 EIM84286.1 - 0.049 13.2 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Ribosomal_S19 PF00203.21 EIM84287.1 - 5.7e-28 96.6 0.1 6.9e-28 96.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 F-box-like PF12937.7 EIM84290.1 - 1.9e-05 24.4 0.1 8.6e-05 22.3 0.1 2.2 1 0 0 1 1 1 1 F-box-like CNOT11 PF10155.9 EIM84291.1 - 1.4e-19 70.4 0.0 2.3e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Asn_synthase PF00733.21 EIM84292.1 - 3.1e-62 211.3 0.0 5.6e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EIM84292.1 - 2.7e-34 117.7 0.0 5.9e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EIM84292.1 - 2.6e-23 82.7 0.0 4.4e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EIM84292.1 - 4e-06 26.4 0.0 7.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EIM84292.1 - 0.24 10.5 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Yip1 PF04893.17 EIM84293.1 - 9.4e-05 22.2 6.6 9.4e-05 22.2 6.6 1.5 1 1 0 1 1 1 1 Yip1 domain SNARE_assoc PF09335.11 EIM84293.1 - 0.0092 16.5 0.4 0.0092 16.5 0.4 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein TctB PF07331.11 EIM84293.1 - 0.37 11.1 8.8 0.56 10.5 8.8 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Pkinase PF00069.25 EIM84294.1 - 6.5e-73 245.3 0.4 6.5e-73 245.3 0.4 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM84294.1 - 1.1e-51 175.6 0.3 1.1e-51 175.6 0.3 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EIM84294.1 - 4.5e-23 81.4 0.0 1.2e-22 80.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 EIM84294.1 - 2.8e-06 27.8 0.1 6.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EIM84294.1 - 9.7e-06 25.1 0.0 2.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIM84294.1 - 2.4e-05 23.3 1.4 3.4e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EIM84294.1 - 0.00049 19.1 0.9 0.00082 18.4 0.9 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIM84294.1 - 0.033 14.1 0.2 0.033 14.1 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family CENP-N PF05238.13 EIM84294.1 - 1.1 8.5 7.5 1.9 7.7 7.5 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CDC45 PF02724.14 EIM84294.1 - 4.6 5.4 7.9 6.1 5.0 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 EIM84295.1 - 1.5e-62 211.8 0.0 1.9e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FolB PF02152.18 EIM84296.1 - 6.7e-13 49.2 0.0 4.2e-12 46.6 0.1 2.0 2 0 0 2 2 2 1 Dihydroneopterin aldolase Glyco_hydro_16 PF00722.21 EIM84297.1 - 0.00036 20.1 0.4 0.0019 17.7 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 ISAV_HA PF06215.11 EIM84297.1 - 0.0086 15.2 0.4 0.15 11.1 0.4 2.1 1 1 0 1 1 1 1 Infectious salmon anaemia virus haemagglutinin Glyco_transf_20 PF00982.21 EIM84298.1 - 6.1e-147 490.1 0.0 8.1e-147 489.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EIM84298.1 - 8.3e-23 80.7 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase RdRP PF05183.12 EIM84299.1 - 6.1e-96 322.4 0.0 9e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase UQ_con PF00179.26 EIM84300.1 - 5e-47 159.1 0.0 5.7e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIM84300.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B EMC1_C PF07774.13 EIM84301.1 - 3.3e-78 262.2 0.0 6.2e-78 261.3 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EIM84301.1 - 1.6e-07 31.2 3.3 0.00098 18.8 0.2 3.1 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 EIM84301.1 - 0.00041 20.1 2.2 0.15 12.0 0.0 4.1 4 0 0 4 4 4 2 PQQ enzyme repeat US22 PF02393.16 EIM84301.1 - 0.0046 17.2 0.8 8.2 6.7 0.0 3.3 2 1 1 3 3 3 2 US22 like STE3 PF02076.15 EIM84303.1 - 2.8e-100 335.3 13.8 3.2e-100 335.1 13.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 EIM84303.1 - 0.00045 20.1 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Bd3614_N PF14442.6 EIM84303.1 - 0.089 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Pheromone PF08015.11 EIM84304.1 - 0.00058 20.9 1.6 0.0065 17.5 1.6 2.0 1 1 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.15 EIM84306.1 - 8.5e-40 136.8 11.1 1e-39 136.5 11.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 EIM84307.1 - 3e-43 148.1 13.0 3.5e-43 147.9 13.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor UPF0182 PF03699.13 EIM84307.1 - 0.063 11.4 1.9 0.069 11.3 1.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) p450 PF00067.22 EIM84308.1 - 4.9e-23 81.6 0.0 1.8e-22 79.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84309.1 - 5.6e-51 173.7 0.0 7.1e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Podoplanin PF05808.11 EIM84310.1 - 0.4 10.8 2.0 0.89 9.6 2.0 1.5 1 0 0 1 1 1 0 Podoplanin p450 PF00067.22 EIM84314.1 - 4.8e-66 223.4 0.0 5.5e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bombinin PF05298.11 EIM84315.1 - 0.087 12.5 0.0 10 5.8 0.0 2.7 3 0 0 3 3 3 0 Bombinin But2 PF09792.9 EIM84316.1 - 3.9e-05 24.1 0.0 4.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 EIM84317.1 - 8.5e-20 71.5 4.9 1.9e-19 70.3 3.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DUF1180 PF06679.12 EIM84318.1 - 10 6.5 6.7 0.98 9.8 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1708 PF08101.11 EIM84319.1 - 3.7e-13 49.4 0.0 4.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 EIM84319.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 RhoGAP domain MLTR_LBD PF17765.1 EIM84319.1 - 0.079 13.1 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain INT_SG_DDX_CT_C PF15300.6 EIM84319.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Sugar_tr PF00083.24 EIM84320.1 - 2.8e-16 59.5 19.8 6.2e-14 51.7 7.2 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EIM84320.1 - 1.2e-15 57.3 48.9 4.2e-10 39.1 37.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 EIM84321.1 - 1.7e-87 290.6 0.0 5e-43 146.7 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM84321.1 - 1.7e-22 79.0 2.9 5e-11 42.2 0.4 3.1 2 1 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 EIM84321.1 - 9e-12 45.2 0.1 5.1e-07 29.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIM84321.1 - 1.2e-11 44.6 0.0 0.00047 19.9 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EIM84321.1 - 4e-11 43.3 0.0 9.7e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EIM84321.1 - 4.3e-10 40.2 3.5 3.3e-05 24.4 0.1 4.1 2 2 2 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 EIM84321.1 - 1.4e-09 38.3 0.0 0.0016 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EIM84321.1 - 2.2e-08 34.5 0.7 0.00098 19.4 0.0 4.3 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EIM84321.1 - 3.2e-08 33.5 0.0 0.00088 19.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EIM84321.1 - 1.2e-07 31.3 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EIM84321.1 - 5.4e-05 23.2 0.0 0.32 11.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 EIM84321.1 - 6e-05 23.0 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EIM84321.1 - 8.5e-05 21.9 0.1 0.096 12.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 EIM84321.1 - 0.00019 20.9 0.9 0.22 10.9 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EIM84321.1 - 0.00025 20.6 0.1 1.3 8.5 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_11 PF13086.6 EIM84321.1 - 0.00062 19.6 0.0 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EIM84321.1 - 0.00077 19.4 0.0 0.081 12.8 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain RNA_helicase PF00910.22 EIM84321.1 - 0.00088 19.6 0.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EIM84321.1 - 0.00097 19.7 0.0 0.083 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EIM84321.1 - 0.001 19.4 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIM84321.1 - 0.0042 16.7 4.8 2.2 7.8 0.1 4.1 2 2 1 4 4 4 1 AAA domain NACHT PF05729.12 EIM84321.1 - 0.005 16.8 0.6 0.17 11.8 0.0 3.3 4 0 0 4 4 3 1 NACHT domain AAA_3 PF07726.11 EIM84321.1 - 0.0059 16.5 0.0 2.7 7.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIM84321.1 - 0.011 15.5 0.0 2 8.1 0.0 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 EIM84321.1 - 0.016 15.1 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.27 EIM84321.1 - 0.018 15.5 0.0 0.55 10.7 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 EIM84321.1 - 0.026 14.3 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EIM84321.1 - 0.028 13.9 0.9 0.63 9.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AFG1_ATPase PF03969.16 EIM84321.1 - 0.029 13.3 0.0 0.56 9.0 0.0 2.6 3 0 0 3 3 3 0 AFG1-like ATPase Sigma54_activ_2 PF14532.6 EIM84321.1 - 0.038 14.1 0.0 9.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 EIM84321.1 - 0.045 13.5 0.4 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIM84321.1 - 0.054 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 EIM84321.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MdcG PF10620.9 EIM84321.1 - 0.07 12.9 0.4 0.19 11.5 0.1 1.8 2 0 0 2 2 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG AAA_19 PF13245.6 EIM84321.1 - 0.1 13.0 0.2 0.9 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EIM84321.1 - 0.12 12.3 0.1 2.4 8.1 0.0 2.7 2 1 1 3 3 2 0 NTPase ATPase PF06745.13 EIM84321.1 - 0.14 11.5 0.1 13 5.0 0.0 2.5 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 EIM84321.1 - 0.15 11.1 0.0 0.55 9.3 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AKAP7_NLS PF10469.9 EIM84322.1 - 1.5e-09 38.1 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DMRT-like PF15791.5 EIM84322.1 - 0.033 14.6 0.6 0.058 13.8 0.6 1.4 1 1 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 FXMRP1_C_core PF12235.8 EIM84322.1 - 0.19 12.3 7.3 0.25 12.0 7.3 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal p450 PF00067.22 EIM84323.1 - 9.5e-60 202.6 0.0 1.1e-59 202.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84324.1 - 1.2e-51 176.0 0.0 1.5e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT_2 PF13279.6 EIM84325.1 - 9.2e-16 58.5 0.0 1.4e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EIM84325.1 - 1.1e-07 32.0 0.6 2.8e-07 30.8 0.0 1.9 3 0 0 3 3 3 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EIM84325.1 - 0.00028 20.2 0.0 0.0091 15.3 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase RRM_1 PF00076.22 EIM84326.1 - 1.5e-76 252.2 0.1 1.1e-19 69.9 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIM84326.1 - 3.3e-05 23.8 0.1 0.82 9.7 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EIM84326.1 - 0.0001 22.1 0.0 0.011 15.6 0.0 3.7 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EIM84326.1 - 0.00037 20.5 0.0 0.61 10.2 0.0 4.6 5 0 0 5 5 5 1 RNA binding motif PHM7_cyt PF14703.6 EIM84326.1 - 0.00037 20.8 0.9 27 4.9 0.0 5.7 5 2 0 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_2 PF04059.12 EIM84326.1 - 0.003 17.8 0.0 6.9 7.0 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif 2 SNF2_N PF00176.23 EIM84327.1 - 7.1e-47 159.8 0.0 1.2e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EIM84327.1 - 3.8e-07 29.9 9.7 6.1e-07 29.2 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM84327.1 - 4.7e-06 26.8 11.5 8.9e-06 26.0 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM84327.1 - 2.1e-05 24.3 12.4 3.6e-05 23.5 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM84327.1 - 7.8e-05 22.5 12.3 0.00014 21.7 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 EIM84327.1 - 0.00032 21.0 0.0 0.00084 19.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 EIM84327.1 - 0.00034 20.4 9.7 0.00063 19.6 9.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EIM84327.1 - 0.00061 20.0 6.7 0.0016 18.7 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EIM84327.1 - 0.0019 18.1 12.2 0.0033 17.4 12.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EIM84327.1 - 0.0067 16.4 1.4 0.015 15.3 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EIM84327.1 - 0.012 15.2 9.8 0.024 14.2 9.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EIM84327.1 - 0.21 11.6 7.0 0.63 10.1 7.0 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 EIM84327.1 - 1.2 9.1 3.9 2.5 8.0 3.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EIM84327.1 - 2 8.6 11.3 4.1 7.6 11.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EIM84327.1 - 2.3 8.1 5.2 8.3 6.3 4.9 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit VWC PF00093.18 EIM84327.1 - 4.6 7.6 9.2 8.4 6.8 9.2 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain NOA36 PF06524.12 EIM84328.1 - 0.19 11.0 13.0 0.38 10.0 13.0 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EIM84328.1 - 0.21 9.9 10.1 0.51 8.6 10.1 1.6 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EIM84328.1 - 2 6.5 23.1 0.013 13.8 14.5 1.6 2 0 0 2 2 2 0 Nop14-like family Myb_DNA-binding PF00249.31 EIM84329.1 - 4.9e-19 68.2 0.1 3.7e-10 39.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIM84329.1 - 1.6e-14 53.9 0.0 5.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EIM84329.1 - 8.5e-05 22.6 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 2 SLIDE VasI PF11319.8 EIM84329.1 - 0.041 13.5 0.1 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 Nop16 PF09420.10 EIM84329.1 - 0.22 11.5 1.5 1.8 8.6 0.8 2.5 2 1 0 2 2 2 0 Ribosome biogenesis protein Nop16 Hamartin PF04388.12 EIM84329.1 - 0.74 8.4 9.8 0.7 8.5 9.8 1.1 1 0 0 1 1 1 0 Hamartin protein PCI PF01399.27 EIM84330.1 - 1.1e-09 38.7 0.0 2.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain zf-C2H2 PF00096.26 EIM84331.1 - 8.6e-10 38.5 10.3 1.4e-05 25.3 0.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM84331.1 - 2.8e-07 30.8 13.7 0.0095 16.7 1.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 EIM84331.1 - 0.0013 19.3 7.6 0.2 12.3 0.7 2.8 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 EIM84331.1 - 0.0096 16.3 8.4 0.38 11.2 0.9 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EIM84331.1 - 0.021 15.3 15.3 0.57 10.7 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.12 EIM84331.1 - 0.035 14.4 6.4 2.6 8.4 2.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.7 EIM84331.1 - 0.051 13.7 3.2 0.53 10.5 0.6 2.6 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_jaz PF12171.8 EIM84331.1 - 0.062 13.6 13.0 0.8 10.1 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 EIM84331.1 - 0.17 12.0 1.8 0.65 10.1 1.0 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger p450 PF00067.22 EIM84332.1 - 3.2e-68 230.6 0.0 4.2e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 STE3 PF02076.15 EIM84333.1 - 2.1e-99 332.4 18.3 2.4e-99 332.2 18.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 EIM84333.1 - 1.6 8.6 5.2 0.39 10.5 0.4 2.1 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor STE3 PF02076.15 EIM84334.1 - 2.1e-27 96.1 10.6 2.6e-27 95.8 10.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor DHR10 PF18595.1 EIM84335.1 - 0.00041 20.4 5.7 0.0008 19.4 5.7 1.4 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DASH_Spc34 PF08657.10 EIM84335.1 - 0.015 15.1 1.1 0.026 14.3 1.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 ABC_tran_CTD PF16326.5 EIM84335.1 - 0.02 15.1 2.5 0.046 14.0 1.7 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4795 PF16043.5 EIM84335.1 - 0.027 14.1 1.3 0.047 13.3 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 EIM84335.1 - 0.045 12.6 1.9 0.065 12.1 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin_2 PF14523.6 EIM84335.1 - 0.076 13.4 1.8 0.16 12.3 1.8 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DUF3328 PF11807.8 EIM84335.1 - 0.086 12.6 1.1 5.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) FliD_N PF02465.18 EIM84335.1 - 0.11 13.2 0.9 0.21 12.3 0.9 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Syntaxin-6_N PF09177.11 EIM84335.1 - 0.43 11.1 4.8 1.3 9.6 4.8 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal FAM76 PF16046.5 EIM84335.1 - 0.89 8.9 2.3 1.3 8.3 2.3 1.2 1 0 0 1 1 1 0 FAM76 protein CLZ PF16526.5 EIM84335.1 - 1.6 9.1 6.6 6.2 7.3 5.8 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels p450 PF00067.22 EIM84336.1 - 8.9e-06 24.7 0.0 1e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84337.1 - 2.6e-55 188.0 0.0 3.1e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84338.1 - 7.1e-63 213.0 0.0 8.9e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 EIM84339.1 - 1e-86 291.6 26.1 1.2e-86 291.4 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM84339.1 - 4.3e-20 71.9 67.6 5.1e-19 68.4 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 EIM84340.1 - 1.6e-09 37.5 0.2 5.8e-09 35.7 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM84340.1 - 0.27 11.2 2.5 2.9 7.9 2.5 2.7 1 1 0 1 1 1 0 F-box domain EBP PF05241.12 EIM84342.1 - 0.12 11.8 12.2 0.22 11.0 12.2 1.4 1 1 0 1 1 1 0 Emopamil binding protein BTB PF00651.31 EIM84343.1 - 0.15 12.3 0.0 11 6.3 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain Phosphorylase PF00343.20 EIM84344.1 - 3e-298 991.0 0.0 3.5e-298 990.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase HA70_C PF17993.1 EIM84344.1 - 0.0051 16.9 0.0 0.6 10.2 0.0 2.7 2 0 0 2 2 2 1 Haemagglutinin 70 C-terminal domain Autophagy_C PF10381.9 EIM84344.1 - 0.34 10.5 1.9 0.73 9.4 1.9 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal F-box-like PF12937.7 EIM84345.1 - 8.2e-08 32.0 0.2 2.5e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like Glyco_hydro_28 PF00295.17 EIM84346.1 - 3.7e-60 203.7 15.5 4.8e-60 203.3 15.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SesA PF17107.5 EIM84347.1 - 0.00014 22.0 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases HeLo PF14479.6 EIM84347.1 - 0.012 15.4 0.9 0.029 14.2 0.9 1.6 1 1 0 1 1 1 0 Prion-inhibition and propagation BAG PF02179.16 EIM84348.1 - 2.7e-07 30.9 0.0 2.7e-07 30.9 0.0 2.9 3 0 0 3 3 3 1 BAG domain AAA_16 PF13191.6 EIM84352.1 - 0.0067 16.8 0.0 0.029 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RHSP PF07999.11 EIM84352.1 - 0.0072 15.2 0.1 2 7.1 0.1 2.4 1 1 0 2 2 2 2 Retrotransposon hot spot protein AAA_11 PF13086.6 EIM84352.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EIM84352.1 - 0.24 10.5 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Retrotran_gag_2 PF14223.6 EIM84353.1 - 0.038 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EIM84353.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Alpha_GJ PF03229.13 EIM84354.1 - 0.0055 17.3 2.8 0.015 15.9 2.8 1.7 1 0 0 1 1 1 1 Alphavirus glycoprotein J Herpes_gE PF02480.16 EIM84354.1 - 0.047 12.4 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EAP30 PF04157.16 EIM84355.1 - 2.7e-34 118.5 0.0 3.6e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EIM84355.1 - 1.9e-19 69.6 0.0 3.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 EIM84355.1 - 0.00012 21.4 11.1 0.0074 15.6 0.9 2.6 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 EIM84355.1 - 0.00021 21.2 4.0 0.042 13.9 0.1 2.8 3 0 0 3 3 3 2 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 EIM84355.1 - 0.011 15.1 1.9 0.011 15.1 1.9 2.8 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 EIM84355.1 - 0.032 14.2 5.1 0.042 13.9 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon OTT_1508_deam PF14441.6 EIM84356.1 - 9.7e-10 38.3 2.1 1.4e-09 37.8 1.2 1.8 2 0 0 2 2 2 1 OTT_1508-like deaminase P53_tetramer PF07710.11 EIM84356.1 - 0.035 13.5 1.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 P53 tetramerisation motif STE PF02200.16 EIM84357.1 - 5.2e-54 181.4 0.0 7.7e-54 180.8 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EIM84357.1 - 2.6e-09 37.0 18.3 2.5e-05 24.5 4.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM84357.1 - 1.6e-06 28.2 7.6 1.6e-06 28.2 7.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM84357.1 - 5.4e-06 26.8 15.1 0.0037 18.0 2.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIM84357.1 - 0.0059 16.6 1.3 0.0059 16.6 1.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM84357.1 - 0.35 11.2 5.0 9.4 6.7 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EIM84357.1 - 0.69 10.3 7.6 0.073 13.4 2.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 EIM84357.1 - 2.5 8.6 5.8 11 6.5 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-MYND PF01753.18 EIM84361.1 - 2e-07 31.0 15.1 3.7e-07 30.1 15.1 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM84361.1 - 0.85 10.0 8.8 1.6 9.1 8.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding BAG PF02179.16 EIM84362.1 - 3.7e-08 33.7 0.1 9.7e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 BAG domain Myelin_MBP PF01669.17 EIM84362.1 - 0.018 15.7 0.3 0.095 13.3 0.0 2.3 1 1 0 2 2 2 0 Myelin basic protein FbpA PF05833.11 EIM84362.1 - 0.082 11.7 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) GspL_C PF12693.7 EIM84365.1 - 0.21 11.4 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 GspL periplasmic domain DUF1687 PF07955.11 EIM84366.1 - 2.4e-19 70.1 0.0 3.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.25 EIM84367.1 - 6.6e-07 29.0 0.1 3e-06 26.8 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM84367.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Zip PF02535.22 EIM84367.1 - 0.25 10.5 2.1 0.39 9.9 2.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RSRP PF17069.5 EIM84367.1 - 0.81 9.2 15.8 1.2 8.6 15.8 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Collagen PF01391.18 EIM84369.1 - 0.022 14.5 7.7 0.039 13.7 7.7 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Glyco_hydro_30 PF02055.16 EIM84370.1 - 9.6e-20 70.8 1.0 1.7e-19 70.1 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EIM84370.1 - 2.9e-14 53.0 0.2 4.6e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EIM84370.1 - 0.0019 17.8 0.1 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 DUF4834 PF16118.5 EIM84371.1 - 0.032 15.2 0.1 0.06 14.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) LapA_dom PF06305.11 EIM84371.1 - 0.14 12.0 0.5 0.21 11.4 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 EIM84372.1 - 0.93 9.6 12.4 2.9 7.9 6.6 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III IBR PF01485.21 EIM84375.1 - 3e-15 56.2 39.2 1.8e-08 34.4 11.5 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain AGH PF17558.2 EIM84376.1 - 0.027 14.6 1.7 0.032 14.4 1.3 1.4 1 1 0 1 1 1 0 Androgenic gland hormone Histone PF00125.24 EIM84379.1 - 1.9e-18 67.1 0.1 2.3e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EIM84379.1 - 2.2e-10 40.1 0.1 3.4e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EIM84379.1 - 0.0023 18.2 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IMS_C PF11799.8 EIM84379.1 - 0.13 13.0 0.0 0.15 12.8 0.0 1.2 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain ASF1_hist_chap PF04729.13 EIM84380.1 - 3.6e-61 205.6 0.0 4.5e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGEF PF00617.19 EIM84381.1 - 1.6e-31 109.8 0.0 4.7e-31 108.3 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EIM84381.1 - 1.4e-10 41.3 2.2 1.5e-10 41.3 0.3 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Glyco_hydro_30 PF02055.16 EIM84383.1 - 1.1e-23 83.8 0.7 1.6e-23 83.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EIM84383.1 - 6.9e-12 45.2 0.2 1.2e-11 44.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Adaptin_N PF01602.20 EIM84384.1 - 6.4e-142 473.8 4.6 8.3e-142 473.4 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EIM84384.1 - 8.1e-60 201.5 1.9 1.2e-58 197.8 0.3 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIM84384.1 - 3.1e-17 62.7 2.8 4.5e-06 27.0 0.0 5.9 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 EIM84384.1 - 2.1e-09 36.8 5.3 0.00033 20.7 0.1 5.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EIM84384.1 - 1.1e-06 29.0 0.2 1.1 9.9 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 EIM84384.1 - 0.0068 16.4 7.0 5.1 7.3 0.0 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EIM84384.1 - 0.011 15.3 0.0 0.7 9.4 0.0 2.8 2 1 0 2 2 2 0 CLASP N terminal RTP1_C1 PF10363.9 EIM84384.1 - 0.012 15.8 1.1 4.6 7.5 0.0 3.9 3 3 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 EIM84384.1 - 0.015 15.2 1.5 0.077 12.9 0.2 2.7 1 1 2 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TIP120 PF08623.10 EIM84384.1 - 0.02 14.7 1.5 0.95 9.2 0.1 3.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) UCH PF00443.29 EIM84385.1 - 8.2e-42 143.5 0.0 1.1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM84385.1 - 5.7e-11 42.6 1.9 2.6e-06 27.2 0.2 2.6 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EIM84385.1 - 3.6e-05 23.4 0.0 7.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2218 PF09981.9 EIM84385.1 - 0.1 13.0 0.6 5.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) TraH PF06122.11 EIM84385.1 - 3.6 6.8 6.5 24 4.0 0.0 2.2 2 0 0 2 2 2 0 Conjugative relaxosome accessory transposon protein ALMT PF11744.8 EIM84385.1 - 5.8 5.6 6.0 8.6 5.1 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Bap31 PF05529.12 EIM84386.1 - 1.6e-44 151.0 7.0 2.4e-44 150.5 7.0 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EIM84386.1 - 1.4e-11 44.2 7.1 1.4e-11 44.2 7.1 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Dynamitin PF04912.14 EIM84386.1 - 0.012 14.9 4.3 0.017 14.4 4.3 1.2 1 0 0 1 1 1 0 Dynamitin PI3K_P85_iSH2 PF16454.5 EIM84386.1 - 0.094 12.3 4.8 0.12 12.0 3.5 1.8 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Peptidase_C14 PF00656.22 EIM84387.1 - 4.8e-35 121.7 0.0 2.5e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 Caspase domain TetR_C_36 PF18598.1 EIM84387.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Peptidase_C14 PF00656.22 EIM84388.1 - 6.9e-19 68.8 0.1 8.2e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EIM84388.1 - 0.001 19.0 0.0 0.94 9.4 0.0 2.2 2 0 0 2 2 2 2 Raptor N-terminal CASPase like domain RNase_H PF00075.24 EIM84389.1 - 0.0001 22.5 0.2 0.00021 21.5 0.0 1.5 2 0 0 2 2 2 1 RNase H Peptidase_C14 PF00656.22 EIM84390.1 - 3.4e-23 82.9 0.0 2.6e-21 76.7 0.0 2.0 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EIM84390.1 - 0.15 12.0 0.0 18 5.3 0.0 2.2 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Fez1 PF06818.15 EIM84391.1 - 1.4 9.3 88.9 0.14 12.6 13.5 5.3 1 1 5 6 6 6 0 Fez1 RINGv PF12906.7 EIM84392.1 - 3.3e-05 23.9 4.9 6.7e-05 22.9 4.9 1.6 1 0 0 1 1 1 1 RING-variant domain PHD_4 PF16866.5 EIM84392.1 - 0.051 13.7 3.8 0.089 12.9 3.8 1.3 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_4 PF13717.6 EIM84392.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_17 PF17120.5 EIM84392.1 - 0.17 11.6 1.1 0.38 10.4 1.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EIM84392.1 - 0.17 12.1 2.6 0.33 11.2 2.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 EIM84392.1 - 0.54 10.6 7.2 1.1 9.6 7.2 1.6 1 1 0 1 1 1 0 Ring finger domain Ogr_Delta PF04606.12 EIM84392.1 - 0.68 10.0 3.9 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger eIF2_C PF09173.11 EIM84393.1 - 1.9e-34 117.7 0.7 4.9e-34 116.4 0.7 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EIM84393.1 - 9.8e-22 77.4 2.4 1.4e-20 73.6 2.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EIM84393.1 - 7.5e-11 42.3 1.9 1.1e-10 41.8 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EIM84393.1 - 0.00036 20.5 0.8 0.006 16.5 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EIM84393.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EIM84393.1 - 0.013 15.5 1.2 0.026 14.5 0.1 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ICMT PF04140.14 EIM84396.1 - 4.2e-15 55.9 0.9 3.3e-13 49.9 0.9 2.1 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM84396.1 - 5.8e-13 49.2 2.7 2.9e-11 43.7 0.3 2.1 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM84396.1 - 4.8e-08 32.2 0.5 5.8e-08 31.9 0.5 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.11 EIM84396.1 - 0.027 14.0 0.7 2.9 7.3 0.1 2.1 2 0 0 2 2 2 0 NnrU protein COX14 PF14880.6 EIM84396.1 - 0.14 12.0 1.2 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.22 EIM84397.1 - 2.7e-14 52.7 0.0 3.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIM84397.1 - 0.0019 18.2 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PPR_2 PF13041.6 EIM84398.1 - 1.3e-05 25.3 0.0 1.2 9.4 0.0 4.5 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 EIM84398.1 - 0.0034 17.5 0.0 2.3 8.7 0.0 3.0 2 0 0 2 2 2 2 PPR repeat IATP PF04568.12 EIM84399.1 - 3.3e-09 37.1 3.9 3.7e-09 36.9 3.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Seryl_tRNA_N PF02403.22 EIM84399.1 - 0.29 11.4 6.7 0.35 11.1 6.7 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATP_sub_h PF10775.9 EIM84400.1 - 2.3e-25 88.3 0.6 3.4e-25 87.8 0.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h RNA_pol PF00940.19 EIM84401.1 - 2.2e-178 593.4 0.0 3e-178 592.9 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EIM84401.1 - 1.5e-91 307.3 0.0 1.5e-91 307.3 0.0 1.8 3 0 0 3 3 3 1 DNA-directed RNA polymerase N-terminal GMC_oxred_N PF00732.19 EIM84403.1 - 1.1e-64 218.7 0.0 1.4e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84403.1 - 2.1e-29 102.9 0.0 3.2e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EIM84403.1 - 0.011 15.0 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM84403.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM84403.1 - 0.034 13.2 0.0 10 5.1 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 EIM84403.1 - 0.054 12.5 0.1 0.085 11.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EIM84403.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Cadherin_C_2 PF16492.5 EIM84404.1 - 0.014 16.2 0.0 0.033 14.9 0.0 1.7 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal EVI2A PF05399.11 EIM84404.1 - 1.2 8.7 3.7 0.34 10.5 0.4 1.6 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) PPR_2 PF13041.6 EIM84405.1 - 0.00079 19.6 0.3 0.16 12.2 0.0 4.3 6 0 0 6 6 6 1 PPR repeat family PPR PF01535.20 EIM84405.1 - 0.0038 17.4 0.3 24 5.4 0.0 5.5 5 1 0 5 5 5 1 PPR repeat Utp14 PF04615.13 EIM84405.1 - 7.3 5.0 19.8 11 4.4 19.8 1.2 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.13 EIM84405.1 - 9.5 6.1 31.8 0.076 13.0 22.0 2.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Ldh_1_C PF02866.18 EIM84406.1 - 2e-41 141.7 0.0 2.6e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EIM84406.1 - 1.4e-40 138.6 0.1 2.1e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EIM84406.1 - 0.0034 16.4 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EIM84406.1 - 0.16 11.3 1.8 3.1 7.1 0.1 3.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRAM_LAG1_CLN8 PF03798.16 EIM84407.1 - 0.034 13.9 6.6 0.073 12.8 6.6 1.5 1 0 0 1 1 1 0 TLC domain FTCD_N PF07837.12 EIM84408.1 - 0.035 13.9 0.0 0.24 11.2 0.0 2.3 3 0 0 3 3 3 0 Formiminotransferase domain, N-terminal subdomain AA_permease_2 PF13520.6 EIM84410.1 - 9.9e-60 202.5 44.0 1.2e-59 202.2 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM84410.1 - 8.8e-13 47.6 37.2 2e-12 46.5 37.2 1.5 1 1 0 1 1 1 1 Amino acid permease Phage_holin_5_1 PF06946.11 EIM84410.1 - 0.0042 17.4 2.0 0.0086 16.4 0.6 2.3 2 0 0 2 2 2 1 Bacteriophage A118-like holin, Hol118 F-box-like PF12937.7 EIM84412.1 - 1.1e-06 28.4 0.3 2.7e-06 27.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM84412.1 - 0.12 12.9 0.2 2.2 8.9 0.0 3.3 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM84412.1 - 0.6 9.9 3.6 18 5.2 0.2 3.9 3 1 0 3 3 3 0 Leucine rich repeat DUF1365 PF07103.11 EIM84413.1 - 1.3e-61 208.4 0.0 1.6e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF913 PF06025.12 EIM84414.1 - 0.23 10.4 4.0 0.33 9.9 4.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Aminotran_3 PF00202.21 EIM84416.1 - 5.3e-45 153.8 0.0 1e-43 149.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III GMC_oxred_N PF00732.19 EIM84419.1 - 1.1e-44 153.0 0.0 3e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84419.1 - 5.2e-29 101.6 0.0 9.8e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM84419.1 - 0.17 12.2 0.1 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain BP28CT PF08146.12 EIM84420.1 - 2.5e-30 105.4 0.1 3e-28 98.7 0.0 3.6 3 1 1 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EIM84420.1 - 2.5e-10 40.7 6.3 2.5e-10 40.7 6.3 3.7 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EIM84420.1 - 0.0047 17.1 4.0 0.12 12.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EIM84420.1 - 0.0086 16.4 7.1 0.4 11.1 0.1 5.7 5 0 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EIM84420.1 - 0.0093 16.5 0.2 26 5.5 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EIM84420.1 - 0.16 12.1 0.2 49 4.0 0.3 3.5 2 1 1 3 3 3 0 Parkin co-regulated protein HEAT_EZ PF13513.6 EIM84420.1 - 3.5 8.2 7.3 15 6.2 0.2 5.0 5 0 0 5 5 5 0 HEAT-like repeat RNA_pol_I_A49 PF06870.12 EIM84421.1 - 1.6e-96 323.5 0.0 2.1e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF3106 PF11304.8 EIM84421.1 - 0.019 15.5 0.4 0.048 14.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Retrotrans_gag PF03732.17 EIM84422.1 - 1.8e-08 34.6 0.0 4.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 EIM84422.1 - 1.2e-06 28.3 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EIM84422.1 - 0.028 14.5 1.3 0.049 13.7 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Transpos_assoc PF13963.6 EIM84427.1 - 0.00018 21.7 0.2 0.2 12.0 0.0 2.2 2 0 0 2 2 2 2 Transposase-associated domain Glyco_transf_17 PF04724.13 EIM84428.1 - 1.5e-138 461.6 0.0 1.7e-138 461.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 F-box-like PF12937.7 EIM84429.1 - 2.7e-06 27.1 0.1 1.1e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM84429.1 - 0.37 11.3 4.8 14 6.2 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) RCR PF12273.8 EIM84433.1 - 9.2e-05 23.1 0.3 0.00013 22.6 0.3 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red BatA PF07584.11 EIM84433.1 - 0.00095 19.5 0.2 0.0015 18.9 0.2 1.2 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal EphA2_TM PF14575.6 EIM84433.1 - 0.004 18.0 0.0 0.0051 17.7 0.0 1.3 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 EIM84433.1 - 0.0076 15.6 8.3 0.012 15.0 8.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sensor PF13796.6 EIM84433.1 - 0.0077 16.3 0.8 0.0091 16.1 0.8 1.1 1 0 0 1 1 1 1 Putative sensor Amnionless PF14828.6 EIM84433.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Rax2 PF12768.7 EIM84433.1 - 0.05 13.0 0.3 0.069 12.6 0.3 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2561 PF10812.8 EIM84433.1 - 0.059 13.4 0.4 0.076 13.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4051 PF13260.6 EIM84433.1 - 0.062 13.0 0.3 0.096 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF2723 PF11028.8 EIM84433.1 - 0.063 13.2 0.5 0.08 12.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) DUF4381 PF14316.6 EIM84433.1 - 0.095 12.9 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Stevor PF17410.2 EIM84433.1 - 0.098 12.2 2.6 0.15 11.6 2.6 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame PMI_typeI PF01238.21 EIM84434.1 - 9.1e-67 225.8 0.0 9e-66 222.6 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EIM84434.1 - 0.0002 21.0 0.6 0.29 10.9 0.4 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EIM84434.1 - 0.0098 15.6 0.2 0.055 13.2 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 EIM84434.1 - 0.013 15.4 0.0 7 6.6 0.0 2.6 2 0 0 2 2 2 0 AraC-like ligand binding domain SSF PF00474.17 EIM84437.1 - 1.4e-17 63.7 28.1 2.7e-17 62.7 28.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Aldo_ket_red PF00248.21 EIM84438.1 - 1.1e-72 244.7 0.0 1.3e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 EIM84438.1 - 0.061 13.3 0.1 9.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Nucleoporin_FG2 PF15967.5 EIM84439.1 - 0.13 10.7 5.6 0.14 10.6 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region SRP9-21 PF05486.12 EIM84440.1 - 9.5e-12 45.2 0.7 4.9e-10 39.7 0.7 2.2 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.17 EIM84440.1 - 0.098 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain DUF1180 PF06679.12 EIM84440.1 - 0.24 11.8 2.9 0.36 11.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) STE3 PF02076.15 EIM84442.1 - 1.2e-84 284.0 9.4 1.3e-84 283.8 9.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor adh_short_C2 PF13561.6 EIM84445.1 - 1.5e-30 106.5 0.9 2.6e-30 105.7 0.9 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM84445.1 - 1.7e-28 99.4 0.1 2.9e-28 98.7 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM84445.1 - 4e-08 33.4 0.1 1.3e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EIM84445.1 - 0.0021 17.5 0.0 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM84445.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EIM84445.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIM84445.1 - 0.02 14.0 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 EIM84445.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM84445.1 - 0.073 12.5 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_hydro_18 PF00704.28 EIM84446.1 - 2e-12 47.5 1.2 2.6e-12 47.1 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mito_carr PF00153.27 EIM84448.1 - 4.6e-56 186.7 3.4 8.7e-20 70.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PigN PF04987.14 EIM84449.1 - 3.8e-132 441.4 2.1 5e-132 441.0 2.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Sulfatase PF00884.23 EIM84449.1 - 0.13 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Sulfatase Phosphodiest PF01663.22 EIM84449.1 - 0.14 11.7 0.2 1.4 8.4 0.1 2.3 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase RRM_1 PF00076.22 EIM84450.1 - 0.0026 17.5 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lyase_N PF09092.11 EIM84450.1 - 0.019 14.9 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Lyase, N terminal RRM_1 PF00076.22 EIM84451.1 - 1e-11 44.5 0.1 0.024 14.4 0.0 5.0 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EIM84451.1 - 0.00099 19.4 0.0 2.4 8.4 0.0 4.3 5 0 0 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RS4NT PF08071.12 EIM84451.1 - 0.0078 16.3 0.9 0.022 14.9 0.1 2.2 2 0 0 2 2 2 1 RS4NT (NUC023) domain Lin-8 PF03353.15 EIM84451.1 - 0.2 11.2 0.1 0.32 10.5 0.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 EIM84454.1 - 0.035 14.0 8.6 0.054 13.4 8.6 1.3 1 1 0 1 1 1 0 SPX domain DUF4551 PF15087.6 EIM84454.1 - 1.6 7.5 5.2 2.5 6.8 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PRCC PF10253.9 EIM84454.1 - 1.9 9.3 9.8 0.038 14.8 2.0 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting OTU PF02338.19 EIM84455.1 - 2e-15 57.4 0.0 3.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EIM84455.1 - 0.023 14.1 0.0 7.5 5.9 0.0 2.2 1 1 1 2 2 2 0 Peptidase C65 Otubain Rubella_E2 PF05749.11 EIM84455.1 - 3.1 7.2 11.9 1 8.7 0.6 2.7 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 SRI PF08236.11 EIM84458.1 - 1.4e-17 63.6 10.3 1.4e-17 63.6 10.3 2.0 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EIM84458.1 - 1.8e-16 61.0 0.3 1.8e-16 61.0 0.3 3.8 2 2 0 2 2 2 1 SET domain AWS PF17907.1 EIM84458.1 - 6.7e-13 48.4 8.8 6.7e-13 48.4 8.8 2.0 2 0 0 2 2 2 1 AWS domain PP28 PF10252.9 EIM84459.1 - 6.8e-26 90.5 14.8 6.8e-26 90.5 14.8 2.5 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Red1 PF07964.11 EIM84459.1 - 4.4 5.4 15.8 5.5 5.1 15.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Complex1_LYR PF05347.15 EIM84460.1 - 1.3e-09 37.9 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EIM84460.1 - 0.00015 22.4 0.0 0.00019 22.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like FAD_binding_3 PF01494.19 EIM84460.1 - 0.16 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Bac_rhamnosid6H PF17389.2 EIM84461.1 - 9.3e-18 64.6 0.0 1.4e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EIM84461.1 - 9.2e-05 22.2 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 EIM84461.1 - 0.00014 20.9 0.1 0.00021 20.3 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_61 PF03443.14 EIM84462.1 - 3.5e-54 183.9 0.0 4.4e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Kelch_1 PF01344.25 EIM84463.1 - 1.8e-33 113.8 10.0 2.9e-08 33.2 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EIM84463.1 - 4.3e-33 113.1 22.7 1e-06 28.6 0.1 6.9 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EIM84463.1 - 3.5e-31 106.7 10.2 3.2e-07 30.2 0.1 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EIM84463.1 - 4e-26 90.8 33.2 4e-07 30.1 0.0 8.6 7 1 1 8 8 8 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EIM84463.1 - 7e-23 80.1 14.5 0.001 19.3 0.0 6.7 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EIM84463.1 - 1.2e-11 44.1 22.6 0.0001 22.1 0.1 7.0 7 0 0 7 7 7 4 Kelch motif SUI1 PF01253.22 EIM84466.1 - 3.5e-17 62.7 0.4 6e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EIM84466.1 - 3.9e-15 56.3 0.0 1.1e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 Pre-PUA-like domain UbiA PF01040.18 EIM84467.1 - 6.7e-23 81.3 5.1 6.7e-23 81.3 5.1 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family DUF5325 PF17259.2 EIM84467.1 - 0.053 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF5480 PF17576.2 EIM84468.1 - 0.88 9.6 3.0 1.8 8.6 2.0 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5480) DUF716 PF04819.12 EIM84470.1 - 0.04 13.6 5.3 0.069 12.8 5.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF716) TAF1D PF15333.6 EIM84470.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D SPX PF03105.19 EIM84471.1 - 8.1 6.2 22.4 25 4.6 22.4 1.7 1 1 0 1 1 1 0 SPX domain Sugar_tr PF00083.24 EIM84473.1 - 1.1e-105 354.1 24.4 1.3e-105 353.9 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM84473.1 - 6.2e-28 97.7 53.7 1.6e-25 89.8 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rtt106 PF08512.12 EIM84474.1 - 5.3e-14 52.4 0.0 9.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EIM84474.1 - 0.0006 19.8 0.0 0.00096 19.1 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain RrnaAD PF00398.20 EIM84475.1 - 9.1e-60 202.0 0.0 1.2e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EIM84475.1 - 1.8e-06 28.5 0.0 3.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM84475.1 - 0.00021 21.9 0.0 0.0004 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM84475.1 - 0.00038 20.1 0.0 0.0007 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EIM84475.1 - 0.00079 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EIM84475.1 - 0.0019 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EIM84475.1 - 0.0021 17.9 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EIM84475.1 - 0.0025 17.1 0.0 0.0054 16.1 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EIM84475.1 - 0.0057 17.4 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EIM84475.1 - 0.044 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_28 PF02636.17 EIM84475.1 - 0.058 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cons_hypoth95 PF03602.15 EIM84475.1 - 0.085 12.5 0.0 0.6 9.7 0.0 2.2 2 1 0 2 2 2 0 Conserved hypothetical protein 95 NodS PF05401.11 EIM84475.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 Nodulation protein S (NodS) Baculo_PEP_C PF04513.12 EIM84476.1 - 0.015 15.4 7.5 0.026 14.6 0.1 3.6 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5316 PF17247.2 EIM84476.1 - 0.021 14.8 0.7 1.2 9.1 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5316) LPP PF04728.13 EIM84476.1 - 0.7 10.3 4.8 16 5.9 0.2 4.2 3 2 2 5 5 5 0 Lipoprotein leucine-zipper LRR_4 PF12799.7 EIM84477.1 - 0.085 13.3 0.2 1.6 9.3 0.4 2.4 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Apt1 PF10351.9 EIM84478.1 - 0.034 13.0 13.6 0.038 12.9 13.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 EIM84478.1 - 0.079 13.0 16.8 0.13 12.3 16.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 EIM84478.1 - 0.72 8.3 18.9 0.83 8.1 18.9 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 EIM84478.1 - 1.8 8.4 18.0 2.4 8.0 18.0 1.2 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 EIM84478.1 - 7.7 5.2 7.6 9.2 4.9 7.6 1.1 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 EIM84480.1 - 6.3e-39 133.9 45.8 7.8e-29 100.7 16.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EIM84480.1 - 3e-05 22.5 4.0 3e-05 22.5 4.0 3.0 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EIM84480.1 - 0.0004 19.4 28.9 0.0015 17.5 10.0 2.8 2 1 0 2 2 2 2 MFS_1 like family UNC-93 PF05978.16 EIM84480.1 - 0.36 10.5 10.0 0.13 12.0 2.5 2.6 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 CPP1-like PF11833.8 EIM84480.1 - 8 6.1 9.0 37 3.9 3.1 3.3 3 1 1 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like zf-CCCH PF00642.24 EIM84481.1 - 6.2e-07 29.2 2.4 1.1e-06 28.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIM84481.1 - 0.00014 21.8 6.7 0.00024 21.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EIM84481.1 - 0.00025 20.7 4.2 0.00053 19.7 4.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 EIM84481.1 - 0.086 13.5 2.6 0.15 12.8 1.4 2.0 1 1 1 2 2 2 0 Torus domain BAG PF02179.16 EIM84482.1 - 1.2e-07 32.0 0.2 5.3e-07 30.0 0.2 2.1 1 0 0 1 1 1 1 BAG domain IQ PF00612.27 EIM84482.1 - 3.5 7.7 10.1 0.028 14.2 1.6 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif F-box-like PF12937.7 EIM84483.1 - 1.9e-05 24.5 0.5 7.4e-05 22.6 0.5 2.1 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 EIM84483.1 - 2.7 8.9 4.1 69 4.6 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Ctr PF04145.15 EIM84484.1 - 8.5e-28 97.8 0.0 1.1e-27 97.5 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3487 PF11990.8 EIM84484.1 - 1.3 8.9 4.4 5.3 7.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Ferric_reduct PF01794.19 EIM84486.1 - 1.1e-19 70.8 6.7 1.1e-19 70.8 6.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EIM84486.1 - 1.5e-09 38.2 0.0 3.4e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIM84486.1 - 1.2e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain Aldo_ket_red PF00248.21 EIM84488.1 - 1.5e-39 135.9 0.0 1.7e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HOOK PF05622.12 EIM84490.1 - 0.25 9.5 1.3 0.38 8.9 1.3 1.1 1 0 0 1 1 1 0 HOOK protein DUF3808 PF10300.9 EIM84491.1 - 1.2e-77 261.7 0.0 4.2e-40 137.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_2 PF07719.17 EIM84491.1 - 0.029 14.5 4.8 2 8.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5480 PF17576.2 EIM84491.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5480) APH PF01636.23 EIM84492.1 - 8.7e-19 68.4 0.0 1.2e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM84492.1 - 1.4e-05 24.8 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EIM84492.1 - 0.023 13.6 0.0 0.047 12.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EIM84492.1 - 0.024 13.9 0.2 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 EIM84492.1 - 0.028 14.0 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EIM84492.1 - 0.087 12.2 0.1 2.1 7.6 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM84493.1 - 0.00016 21.7 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM84493.1 - 0.00073 19.2 0.0 0.001 18.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase STE3 PF02076.15 EIM84494.1 - 7.4e-100 333.9 21.7 8.6e-100 333.7 21.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor zf-MYND PF01753.18 EIM84495.1 - 7.2e-10 38.8 9.4 7.2e-10 38.8 9.4 2.4 2 0 0 2 2 2 1 MYND finger RNase_T PF00929.24 EIM84496.1 - 4.9e-06 27.2 0.0 7.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease F-box-like PF12937.7 EIM84500.1 - 5.1e-06 26.3 0.1 1.4e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM84501.1 - 4e-08 33.0 0.5 4e-08 33.0 0.5 2.5 3 0 0 3 3 3 1 F-box-like Aldedh PF00171.22 EIM84503.1 - 1.8e-79 267.4 0.0 2.2e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.18 EIM84503.1 - 0.0094 16.8 0.0 0.025 15.5 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family CorA PF01544.18 EIM84503.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Glyco_hydro_38N PF01074.22 EIM84504.1 - 2.1e-78 263.7 0.1 3.5e-78 262.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EIM84504.1 - 3.9e-51 174.2 0.0 7.7e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EIM84504.1 - 1.6e-25 89.1 0.0 4.3e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EIM84504.1 - 8.2e-06 25.8 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Ferritin_2 PF13668.6 EIM84505.1 - 4.5e-38 130.5 2.7 7e-38 129.9 2.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain Pkinase_Tyr PF07714.17 EIM84507.1 - 0.0052 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_1 PF00667.20 EIM84508.1 - 2.3e-35 122.2 0.0 7e-35 120.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EIM84508.1 - 3.7e-30 105.0 0.0 6e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EIM84508.1 - 4.9e-11 43.2 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EIM84508.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 Flavodoxin domain SNase PF00565.17 EIM84511.1 - 2.4e-18 66.6 0.3 4.5e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Staphylococcal nuclease homologue DUF737 PF05300.11 EIM84511.1 - 0.031 14.6 1.8 0.091 13.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF737) PRIMA1 PF16101.5 EIM84511.1 - 2.1 8.4 9.5 3.5 7.7 9.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MelC1 PF06236.11 EIM84512.1 - 0.65 10.1 4.4 0.6 10.2 0.3 2.2 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Yip1 PF04893.17 EIM84513.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain CD34_antigen PF06365.12 EIM84513.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 EIM84513.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family SNF2_N PF00176.23 EIM84514.1 - 1.1e-59 202.0 0.6 2.3e-59 200.9 0.6 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM84514.1 - 1.5e-18 67.1 0.0 1.6e-17 63.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM84514.1 - 3.6e-07 30.3 0.1 7.7e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EIM84514.1 - 4.9e-07 29.6 0.1 7.5e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-RING_UBOX PF13445.6 EIM84514.1 - 0.00022 21.2 0.9 0.00062 19.7 0.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIM84514.1 - 0.0027 17.6 3.0 0.01 15.7 3.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM84514.1 - 0.0073 16.2 3.2 0.022 14.7 3.2 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM84514.1 - 0.0093 15.8 1.2 0.0093 15.8 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM84514.1 - 0.034 14.3 0.6 0.034 14.3 0.6 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AAA_34 PF13872.6 EIM84514.1 - 0.058 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EIM84514.1 - 0.084 13.2 4.6 0.047 14.0 1.2 2.2 2 0 0 2 2 2 0 Ring finger domain FYVE PF01363.21 EIM84514.1 - 0.11 12.6 1.3 0.27 11.4 1.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger Cytochrome_C7 PF14522.6 EIM84514.1 - 0.37 10.8 3.5 6 6.9 3.5 2.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-4CXXC_R1 PF10497.9 EIM84514.1 - 1.3 9.3 3.8 2.1 8.6 1.4 2.2 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PALP PF00291.25 EIM84517.1 - 5.2e-66 223.1 0.3 5.7e-66 222.9 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 EIM84517.1 - 0.22 11.3 1.6 0.25 11.1 0.4 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein zf-MYND PF01753.18 EIM84518.1 - 9.6e-10 38.4 13.1 9.6e-10 38.4 13.1 2.4 2 0 0 2 2 2 1 MYND finger SDA1 PF05285.12 EIM84519.1 - 0.00044 19.8 1.8 0.0005 19.6 1.8 1.3 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EIM84519.1 - 0.083 12.2 7.2 0.11 11.8 7.2 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EIM84519.1 - 1.1 9.0 5.5 1.5 8.4 4.1 2.0 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 EIM84519.1 - 1.3 8.9 8.4 1.9 8.3 8.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 EIM84519.1 - 1.4 7.0 14.1 1.8 6.7 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 EIM84519.1 - 7 5.7 23.4 15 4.6 23.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.32 EIM84525.1 - 2.2e-05 25.1 2.5 0.0037 18.1 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM84525.1 - 0.00047 20.4 3.0 1.8 9.0 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SfLAP PF11139.8 EIM84525.1 - 0.12 11.8 1.0 0.25 10.8 1.0 1.4 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Dynamin_M PF01031.20 EIM84526.1 - 0.00018 20.9 0.2 0.00024 20.4 0.2 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 EIM84526.1 - 0.0012 19.0 0.1 0.0038 17.4 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Sec63 PF02889.16 EIM84526.1 - 0.041 13.0 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Sec63 Brl domain F-box-like PF12937.7 EIM84527.1 - 4.7e-05 23.2 1.5 0.00016 21.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like Melittin PF01372.17 EIM84527.1 - 0.12 12.4 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 Melittin APG6_N PF17675.1 EIM84529.1 - 0.025 15.1 0.5 0.046 14.2 0.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3445 PF11927.8 EIM84529.1 - 0.041 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) CLZ PF16526.5 EIM84529.1 - 0.29 11.5 1.5 0.56 10.6 1.5 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4404 PF14357.6 EIM84529.1 - 0.43 11.2 2.1 1.5 9.5 2.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Med13_C PF06333.12 EIM84533.1 - 0.031 13.6 0.1 0.031 13.6 0.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain F-box_4 PF15966.5 EIM84535.1 - 0.055 13.4 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 F-box F-box PF00646.33 EIM84535.1 - 0.067 13.1 0.8 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 F-box domain AMO PF02461.16 EIM84536.1 - 0.022 14.5 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase Transposase_21 PF02992.14 EIM84541.1 - 7.6e-06 25.3 0.0 1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 HLH PF00010.26 EIM84548.1 - 1.5e-10 40.9 0.0 3.7e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 EIM84548.1 - 2.2 6.5 4.2 3.6 5.7 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein AT_hook PF02178.19 EIM84548.1 - 2.3 8.4 9.6 0.7 10.0 5.7 2.4 2 0 0 2 2 2 0 AT hook motif YL1 PF05764.13 EIM84548.1 - 9.7 6.2 16.1 2.5 8.1 12.1 2.0 1 1 1 2 2 2 0 YL1 nuclear protein F-box-like PF12937.7 EIM84551.1 - 1.3e-06 28.2 2.0 4.7e-06 26.4 2.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM84551.1 - 0.069 13.1 1.3 0.49 10.3 0.2 2.8 3 0 0 3 3 3 0 F-box domain TetR_C_32 PF09209.11 EIM84552.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Hom_end_hint PF05203.16 EIM84553.1 - 0.028 14.4 0.3 0.055 13.4 0.2 1.6 2 0 0 2 2 2 0 Hom_end-associated Hint Peptidase_M24 PF00557.24 EIM84554.1 - 1e-05 25.4 0.1 1e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CIDE-N PF02017.15 EIM84554.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 CIDE-N domain BLUF PF04940.12 EIM84557.1 - 0.023 14.8 0.1 0.12 12.5 0.1 2.0 1 1 1 2 2 2 0 Sensors of blue-light using FAD PDCD9 PF07147.12 EIM84557.1 - 0.19 10.9 0.1 0.24 10.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) Zn_clus PF00172.18 EIM84558.1 - 3.5e-10 39.8 22.6 6e-08 32.7 9.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Cauli_VI PF01693.16 EIM84559.1 - 0.0024 18.1 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin zf-RING_UBOX PF13445.6 EIM84562.1 - 1.7e-07 31.1 2.0 1.7e-07 31.1 2.0 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIM84562.1 - 4.8e-06 26.4 9.0 8e-05 22.5 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM84562.1 - 1.2e-05 25.1 5.6 1.2e-05 25.1 5.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM84562.1 - 1.2e-05 25.5 10.9 0.00012 22.3 7.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EIM84562.1 - 6.5e-05 23.0 7.5 0.0017 18.5 4.5 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EIM84562.1 - 0.00015 21.5 14.7 0.00019 21.2 9.1 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM84562.1 - 0.0011 18.8 12.7 0.021 14.7 2.9 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EIM84562.1 - 0.0059 16.4 12.1 0.071 13.0 8.6 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 EIM84562.1 - 0.044 14.0 4.1 0.046 14.0 1.3 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_ribbon_17 PF17120.5 EIM84562.1 - 0.3 10.7 6.7 7.2 6.3 7.1 2.5 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EIM84562.1 - 0.36 10.7 8.1 10 6.0 5.3 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EIM84562.1 - 1.4 9.3 13.2 0.62 10.4 8.2 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain FYVE PF01363.21 EIM84562.1 - 1.4 9.1 7.7 4.3 7.5 8.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger DUF4329 PF14220.6 EIM84563.1 - 0.15 12.1 0.3 0.32 11.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) Transposase_21 PF02992.14 EIM84565.1 - 1.1e-06 28.1 0.0 1.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 RNA_pol_Rpb2_7 PF04560.20 EIM84565.1 - 0.079 13.4 0.0 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 EPTP PF03736.17 EIM84566.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 EPTP domain Plavaka PF18759.1 EIM84567.1 - 2.9e-88 296.2 0.0 1.5e-67 228.1 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase DUF4158 PF13700.6 EIM84567.1 - 0.077 12.8 0.1 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) SesA PF17107.5 EIM84569.1 - 0.023 14.9 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Flagellin_N PF00669.20 EIM84569.1 - 0.072 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF3510 PF12022.8 EIM84569.1 - 0.091 13.1 0.0 1.6 9.1 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) zf-C2H2 PF00096.26 EIM84570.1 - 0.00044 20.6 15.4 0.087 13.3 3.8 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM84570.1 - 0.0012 19.5 18.8 0.18 12.7 2.9 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM84570.1 - 0.0028 18.0 1.7 0.0028 18.0 1.7 3.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 EIM84570.1 - 0.13 12.6 6.0 1.9 8.9 0.7 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 EIM84570.1 - 0.93 9.6 3.3 1.1 9.4 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger domain Cauli_VI PF01693.16 EIM84571.1 - 3.1e-05 24.2 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin Zn_clus PF00172.18 EIM84572.1 - 5e-10 39.3 8.6 5e-10 39.3 8.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIM PF04434.17 EIM84576.1 - 8.4e-07 28.5 0.5 2.2e-06 27.2 0.5 1.8 1 0 0 1 1 1 1 SWIM zinc finger DUF1390 PF07150.11 EIM84577.1 - 0.27 10.9 0.7 0.81 9.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) 2OG-FeII_Oxy_3 PF13640.6 EIM84578.1 - 0.0093 16.8 0.1 0.022 15.7 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4218 PF13960.6 EIM84579.1 - 0.04 13.5 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RVT_1 PF00078.27 EIM84580.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3774 PF12609.8 EIM84580.1 - 0.054 14.5 0.1 0.11 13.5 0.1 1.5 1 0 0 1 1 1 0 Wound-induced protein DUF805 PF05656.14 EIM84580.1 - 0.096 13.1 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) KDZ PF18758.1 EIM84581.1 - 7.8e-35 120.5 3.0 1.2e-22 80.6 0.0 3.2 3 0 0 3 3 3 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM84581.1 - 4.7e-31 107.1 0.0 9.1e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM84581.1 - 0.00029 20.9 0.0 0.00061 19.9 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EIM84581.1 - 0.024 14.5 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases EPSP_synthase PF00275.20 EIM84582.1 - 6.2e-84 282.1 0.3 9.9e-84 281.4 0.3 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EIM84582.1 - 4.4e-67 226.0 0.0 8.8e-67 225.0 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DUF1708 PF08101.11 EIM84582.1 - 2.6e-13 50.0 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Fe-ADH_2 PF13685.6 EIM84582.1 - 0.0006 19.6 1.0 0.21 11.3 0.0 3.4 2 1 0 3 3 3 1 Iron-containing alcohol dehydrogenase Peptidase_C7 PF01830.18 EIM84582.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase C7 family SARG PF15385.6 EIM84583.1 - 0.46 9.7 3.9 0.8 8.9 3.9 1.4 1 1 0 1 1 1 0 Specifically androgen-regulated gene protein GMC_oxred_N PF00732.19 EIM84584.1 - 3.4e-57 194.1 0.0 4.5e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84584.1 - 1.3e-34 119.8 0.0 2.3e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM84584.1 - 0.0002 21.5 0.2 0.013 15.7 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM84584.1 - 0.00045 19.4 0.1 0.00075 18.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM84584.1 - 0.00051 19.2 0.2 0.013 14.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EIM84584.1 - 0.0026 17.4 0.5 0.01 15.5 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM84584.1 - 0.0036 16.6 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EIM84584.1 - 0.072 11.8 0.2 2 7.0 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 EIM84584.1 - 0.12 11.6 0.1 0.59 9.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UQ_con PF00179.26 EIM84586.1 - 2.6e-40 137.3 0.0 3.5e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MSA-2c PF12238.8 EIM84586.1 - 1.2 9.1 13.3 1.9 8.5 13.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pneumo_att_G PF05539.11 EIM84586.1 - 3.4 7.2 11.3 5.8 6.4 11.3 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G O-FucT PF10250.9 EIM84587.1 - 4.9e-10 39.6 0.0 6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase 4HBT_2 PF13279.6 EIM84588.1 - 2.3e-08 34.6 0.0 3.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily COesterase PF00135.28 EIM84589.1 - 4.6e-94 316.1 0.0 6.2e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM84589.1 - 1.6e-07 31.4 0.2 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM84589.1 - 0.002 17.7 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family ABC1 PF03109.16 EIM84592.1 - 9.8e-26 90.3 0.0 1.7e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family GST_N PF02798.20 EIM84594.1 - 3.2e-20 72.3 0.0 5.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM84594.1 - 1.3e-17 63.9 0.0 2.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM84594.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM84594.1 - 1.1e-08 35.2 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM84594.1 - 6e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM84594.1 - 0.00059 19.8 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM84594.1 - 0.084 13.6 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 EIM84594.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Sacchrp_dh_NADP PF03435.18 EIM84595.1 - 2.3e-17 63.5 0.0 3.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EIM84595.1 - 2.4e-06 27.6 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM84595.1 - 0.0015 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM84595.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EIM84595.1 - 0.004 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EIM84595.1 - 0.0061 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Arabinose_trans PF04602.12 EIM84595.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein adh_short PF00106.25 EIM84595.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 EIM84595.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EIM84595.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EIM84595.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase EF-hand_9 PF14658.6 EIM84595.1 - 0.16 12.3 0.0 0.51 10.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain 3Beta_HSD PF01073.19 EIM84595.1 - 0.19 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cwf_Cwc_15 PF04889.12 EIM84597.1 - 0.36 10.5 5.9 0.75 9.5 5.3 1.7 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MspA PF09203.11 EIM84598.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 MspA TLD PF07534.16 EIM84600.1 - 2.1e-32 112.3 0.0 4e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 TLD OTT_1508_deam PF14441.6 EIM84602.1 - 0.0033 17.4 5.5 0.0033 17.4 5.5 2.0 2 1 0 2 2 2 1 OTT_1508-like deaminase Prismane PF03063.20 EIM84602.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Pkinase_Tyr PF07714.17 EIM84603.1 - 1.9e-50 171.6 0.0 4.4e-50 170.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM84603.1 - 8.9e-38 130.2 0.0 2.1e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EIM84603.1 - 0.00069 19.0 0.7 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIM84603.1 - 0.0043 16.7 0.2 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EIM84603.1 - 0.054 13.4 0.4 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family AcetDehyd-dimer PF09290.11 EIM84608.1 - 0.02 15.1 1.2 0.057 13.6 0.9 1.7 1 1 1 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Gti1_Pac2 PF09729.9 EIM84610.1 - 1.1e-29 103.9 0.3 6.5e-26 91.5 0.2 2.3 1 1 0 2 2 2 2 Gti1/Pac2 family HHH_8 PF14716.6 EIM84612.1 - 0.002 18.5 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Myc_N PF01056.18 EIM84612.1 - 0.015 15.2 5.2 0.015 15.2 5.2 2.0 2 0 0 2 2 2 0 Myc amino-terminal region FAM83 PF07894.12 EIM84612.1 - 0.15 11.6 1.9 0.23 11.0 1.9 1.2 1 0 0 1 1 1 0 FAM83 A-H FAM176 PF14851.6 EIM84612.1 - 0.94 9.1 8.5 0.87 9.2 4.3 2.1 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 EIM84612.1 - 2.4 8.6 7.8 2.5 8.6 2.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIIE-A_C PF11521.8 EIM84612.1 - 6.6 7.1 15.6 0.63 10.4 6.8 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha PBP1_TM PF14812.6 EIM84612.1 - 7.9 6.9 13.9 16 5.9 5.4 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4588 PF15251.6 EIM84613.1 - 0.00021 21.2 0.1 0.00023 21.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Methyltransf_22 PF13383.6 EIM84616.1 - 4.5e-20 72.3 0.0 2.3e-15 56.9 0.1 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 EIM84616.1 - 7.5e-08 32.6 0.0 1.4e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain Paramyxo_C PF01692.18 EIM84618.1 - 0.0069 15.8 0.3 0.015 14.7 0.3 1.5 1 0 0 1 1 1 1 Paramyxovirus non-structural protein C zf-C2H2_4 PF13894.6 EIM84618.1 - 0.092 13.6 15.5 1.4 10.0 0.0 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger RIFIN PF02009.16 EIM84619.1 - 0.0006 19.8 0.1 0.00085 19.3 0.1 1.1 1 0 0 1 1 1 1 Rifin DUF2749 PF10907.8 EIM84619.1 - 0.037 14.2 2.9 2.3 8.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) DUF2207 PF09972.9 EIM84619.1 - 0.06 12.1 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 EIM84619.1 - 0.089 12.7 4.6 0.049 13.5 1.2 2.1 1 1 1 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 EIM84619.1 - 0.18 12.2 4.1 0.091 13.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Adeno_E3_CR2 PF02439.15 EIM84619.1 - 0.19 11.5 1.2 0.42 10.4 1.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ApoO PF09769.9 EIM84620.1 - 1.2e-26 93.2 0.5 3.6e-26 91.7 0.0 2.0 3 0 0 3 3 3 1 Apolipoprotein O Apolipoprotein PF01442.18 EIM84620.1 - 0.0018 18.2 1.6 0.0018 18.2 1.6 2.4 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EIM84620.1 - 0.1 13.2 7.5 2.3 8.9 0.5 3.9 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) TBCA PF02970.16 EIM84620.1 - 6.5 7.2 8.4 0.36 11.2 1.7 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A Gp_dh_C PF02800.20 EIM84622.1 - 0.071 12.7 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF2749 PF10907.8 EIM84623.1 - 0.024 14.8 3.5 5.5 7.2 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) TMEM154 PF15102.6 EIM84623.1 - 0.038 13.9 0.3 0.038 13.9 0.3 1.8 2 0 0 2 2 2 0 TMEM154 protein family RIFIN PF02009.16 EIM84623.1 - 0.064 13.1 0.1 0.09 12.7 0.1 1.2 1 0 0 1 1 1 0 Rifin Shisa PF13908.6 EIM84623.1 - 0.069 13.4 2.4 0.11 12.7 0.2 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator CcmD PF04995.14 EIM84623.1 - 0.83 9.8 3.1 1.2 9.3 1.7 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2981 PF11200.8 EIM84625.1 - 1.3 8.7 2.9 2.4 7.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) TRAP_alpha PF03896.16 EIM84627.1 - 0.0032 16.7 1.0 0.0066 15.7 0.0 1.8 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit K_channel_TID PF07941.11 EIM84627.1 - 1.3 9.5 9.9 3.7 8.1 0.1 3.5 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain AAA PF00004.29 EIM84628.1 - 8e-15 55.4 0.0 1.4e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM84628.1 - 0.0066 16.5 0.0 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM84628.1 - 0.0081 16.4 2.1 0.062 13.6 0.4 2.4 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EIM84628.1 - 0.016 14.5 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.14 EIM84628.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DnaB_C PF03796.15 EIM84628.1 - 0.06 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EIM84628.1 - 0.16 12.3 3.7 0.31 11.4 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain ATPase PF06745.13 EIM84628.1 - 0.2 11.0 1.3 0.4 10.0 0.4 1.8 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 EIM84629.1 - 6.7e-07 29.4 0.0 2.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EIM84629.1 - 4.6e-06 27.1 0.0 4.6e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM84629.1 - 0.00057 20.2 0.0 0.0024 18.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EIM84629.1 - 0.0038 16.5 0.0 0.0083 15.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 EIM84629.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GMC_oxred_N PF00732.19 EIM84630.1 - 7.8e-64 215.9 0.0 9.8e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84630.1 - 4.9e-31 108.2 0.0 9.1e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM84630.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ABC_membrane PF00664.23 EIM84632.1 - 3.4e-48 164.7 22.4 6.1e-27 95.0 6.6 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EIM84632.1 - 9.2e-48 162.2 0.0 1.5e-27 96.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EIM84632.1 - 7.5e-08 32.5 2.3 0.23 11.2 0.1 4.5 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIM84632.1 - 1.8e-07 30.8 0.0 0.025 14.0 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EIM84632.1 - 1.4e-05 24.4 0.0 0.035 13.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 EIM84632.1 - 1.9e-05 24.3 0.1 0.3 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EIM84632.1 - 3.8e-05 24.1 0.1 0.44 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EIM84632.1 - 5.5e-05 22.8 0.0 0.069 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EIM84632.1 - 0.00011 22.8 0.0 0.03 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EIM84632.1 - 0.0048 17.0 0.1 0.022 14.9 0.1 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EIM84632.1 - 0.018 15.3 0.5 25 5.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 EIM84632.1 - 0.028 13.8 0.1 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EIM84632.1 - 0.056 13.5 0.2 2.9 8.0 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM84632.1 - 0.081 12.8 0.0 21 5.0 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase DUF3123 PF11321.8 EIM84632.1 - 0.12 13.1 0.4 0.3 11.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) AAA_7 PF12775.7 EIM84632.1 - 0.17 11.4 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RseC_MucC PF04246.12 EIM84632.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.6 3 0 0 3 3 2 0 Positive regulator of sigma(E), RseC/MucC CCDC144C PF14915.6 EIM84633.1 - 0.0051 16.0 2.3 0.0058 15.8 2.3 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF2046 PF09755.9 EIM84633.1 - 0.0087 15.3 2.2 0.0091 15.3 2.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Fez1 PF06818.15 EIM84633.1 - 0.016 15.6 3.7 0.019 15.4 3.7 1.1 1 0 0 1 1 1 0 Fez1 Jnk-SapK_ap_N PF09744.9 EIM84633.1 - 0.027 14.7 2.9 0.027 14.7 2.5 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 TMPIT PF07851.13 EIM84633.1 - 0.13 11.5 0.7 0.15 11.3 0.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF1043 PF06295.12 EIM84633.1 - 0.16 12.0 2.1 0.34 10.9 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) ZapB PF06005.12 EIM84633.1 - 0.23 12.0 4.3 0.25 11.8 3.7 1.4 1 1 0 1 1 1 0 Cell division protein ZapB GIT_CC PF16559.5 EIM84633.1 - 0.33 10.9 3.1 0.21 11.5 1.1 1.8 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 EIM84633.1 - 0.72 10.8 6.5 2 9.4 0.9 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DEAD PF00270.29 EIM84638.1 - 0.00023 21.0 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OrsD PF12013.8 EIM84638.1 - 0.0046 17.4 0.1 0.015 15.8 0.1 1.9 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Helicase_C PF00271.31 EIM84638.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain KptA_kDCL PF18176.1 EIM84641.1 - 0.073 12.9 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain HNH_2 PF13391.6 EIM84642.1 - 0.00019 21.5 0.1 0.00039 20.5 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease MR_MLE_C PF13378.6 EIM84643.1 - 1.8e-47 161.7 0.8 1.5e-46 158.7 0.8 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EIM84643.1 - 8.7e-08 32.4 0.0 2.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MFS_1 PF07690.16 EIM84644.1 - 7.2e-31 107.4 32.4 2e-30 105.9 31.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 EIM84645.1 - 1.7e-16 60.3 0.0 8.9e-16 58.0 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Activator-TraM PF11657.8 EIM84645.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 Transcriptional activator TraM DegT_DnrJ_EryC1 PF01041.17 EIM84645.1 - 0.039 13.3 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family COesterase PF00135.28 EIM84646.1 - 1.4e-66 225.5 0.0 1.8e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM84646.1 - 0.0071 16.2 0.1 0.1 12.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 EIM84647.1 - 8.7e-11 41.3 0.9 1.4e-10 40.7 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM84647.1 - 1.8e-06 27.9 7.1 3.6e-06 27.0 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHAT PF12770.7 EIM84649.1 - 1.3e-37 129.8 0.0 2.1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM84649.1 - 1.2e-36 123.6 16.0 0.00018 21.3 0.1 14.4 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_12 PF13424.6 EIM84649.1 - 3.1e-17 62.6 20.0 0.075 13.3 0.0 11.9 8 5 4 12 12 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 EIM84649.1 - 3.5e-13 49.0 9.0 0.18 11.5 0.1 11.0 11 0 0 11 11 11 2 TPR repeat TPR_8 PF13181.6 EIM84649.1 - 2.4e-12 46.0 2.3 13 6.3 0.0 11.4 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM84649.1 - 8e-08 31.8 10.9 4 7.8 0.0 11.4 14 0 0 14 14 12 1 Tetratricopeptide repeat CRISPR_Cse2 PF09485.10 EIM84649.1 - 6.5e-07 30.0 5.8 12 6.4 0.0 7.2 2 1 1 6 6 6 1 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_1 PF00515.28 EIM84649.1 - 4.1e-06 26.4 15.9 2.1 8.3 0.0 10.8 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM84649.1 - 2.7e-05 24.6 15.5 9 7.4 0.0 8.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM84649.1 - 2.9e-05 23.8 12.2 3.4 7.9 0.0 9.3 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIM84649.1 - 0.0036 17.6 6.0 0.86 10.1 0.0 6.1 8 0 0 8 8 6 1 Tetratricopeptide repeat GDE_N PF12439.8 EIM84649.1 - 0.0075 15.7 0.0 37 3.6 0.0 4.5 3 2 2 5 5 5 0 Glycogen debranching enzyme N terminal TPR_16 PF13432.6 EIM84649.1 - 0.028 15.1 15.6 5.9 7.6 0.1 6.8 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIM84649.1 - 0.28 11.7 10.1 19 5.9 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EIM84649.1 - 0.39 9.9 5.5 32 3.6 0.0 4.9 6 1 0 6 6 6 0 Tetratricopeptide repeat Peptidase_S10 PF00450.22 EIM84650.1 - 1.5e-85 288.2 0.0 1.8e-85 287.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 EIM84651.1 - 2.5e-57 189.5 30.4 6e-10 39.6 0.3 7.2 7 0 0 7 7 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM84651.1 - 6.9e-22 77.6 0.7 0.01 16.1 0.0 6.4 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM84651.1 - 2e-07 30.3 0.1 1.7 7.5 0.0 5.9 1 1 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIM84651.1 - 6.5e-07 29.1 0.1 3.8 7.6 0.0 6.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 EIM84651.1 - 1.4e-06 28.8 0.0 3.9e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PQQ_3 PF13570.6 EIM84651.1 - 2.8e-05 24.5 4.6 1.2 9.7 0.0 5.7 4 2 2 6 6 6 1 PQQ-like domain Proteasome_A_N PF10584.9 EIM84651.1 - 0.00034 20.2 5.9 47 3.8 0.1 5.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 EIM84651.1 - 0.0012 18.8 0.2 0.0035 17.3 0.2 1.7 1 1 0 1 1 1 1 NACHT domain Peptidase_S9_N PF02897.15 EIM84651.1 - 0.014 14.2 0.4 6.5 5.4 0.0 3.6 1 1 3 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF815 PF05673.13 EIM84651.1 - 0.047 12.8 0.0 9.2 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) WD40_like PF17005.5 EIM84651.1 - 0.056 12.8 0.0 24 4.1 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain AAA PF00004.29 EIM84651.1 - 0.077 13.4 0.1 0.46 10.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Frtz PF11768.8 EIM84651.1 - 0.086 11.1 0.0 58 1.8 0.0 3.9 2 2 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz NB-ARC PF00931.22 EIM84651.1 - 0.087 12.0 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 EIM84651.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EIM84651.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.14 EIM84651.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF3952 PF13130.6 EIM84651.1 - 0.18 12.0 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) CHAP PF05257.16 EIM84651.1 - 0.98 10.0 6.0 5.9 7.5 0.1 3.4 2 1 1 4 4 3 0 CHAP domain Peptidase_S10 PF00450.22 EIM84653.1 - 4.4e-07 29.7 0.0 5.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase p450 PF00067.22 EIM84654.1 - 1.9e-60 204.9 0.0 1.6e-59 201.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pox_D5 PF03288.16 EIM84654.1 - 0.19 12.3 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like SKG6 PF08693.10 EIM84657.1 - 6.1e-05 22.4 0.5 0.00011 21.5 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Fil_haemagg PF05594.14 EIM84657.1 - 0.42 11.2 13.0 0.11 13.0 5.4 2.8 2 1 0 2 2 2 0 Haemagluttinin repeat BTB PF00651.31 EIM84659.1 - 0.00017 21.8 0.0 0.00043 20.5 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_115 PF15979.5 EIM84659.1 - 0.076 12.4 0.1 0.14 11.6 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 115 Aldolase_II PF00596.21 EIM84660.1 - 1.7e-28 99.8 0.1 2.3e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAA_hydrolase PF01557.18 EIM84661.1 - 5.1e-51 173.4 0.1 7.4e-51 172.9 0.1 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF4124 PF13511.6 EIM84661.1 - 0.037 14.4 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) adh_short PF00106.25 EIM84663.1 - 8.1e-31 107.0 0.3 1.1e-30 106.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84663.1 - 7.2e-25 87.9 0.1 9.2e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EIM84663.1 - 2e-08 34.3 0.1 7.3e-08 32.5 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM84663.1 - 3.4e-05 23.8 1.9 8.9e-05 22.5 1.9 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM84663.1 - 0.0027 17.2 0.2 0.008 15.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EIM84663.1 - 0.024 14.9 0.2 0.037 14.3 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 EIM84663.1 - 0.037 13.6 0.3 0.055 13.0 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family Transp_cyt_pur PF02133.15 EIM84664.1 - 2.3e-77 260.6 29.8 2.7e-77 260.4 29.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LamB_YcsF PF03746.16 EIM84665.1 - 5.8e-82 275.0 0.0 6.5e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family JmjN PF02375.17 EIM84665.1 - 0.43 10.6 1.2 14 5.8 0.1 2.8 3 0 0 3 3 3 0 jmjN domain DUF220 PF02713.14 EIM84666.1 - 0.062 13.4 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF220 DUF3246 PF11596.8 EIM84668.1 - 0.065 12.7 1.5 0.1 12.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CT_A_B PF02626.15 EIM84669.1 - 3e-76 256.5 0.3 4.5e-76 256.0 0.3 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 EIM84669.1 - 6e-54 182.7 0.0 1.1e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 EIM84669.1 - 2.6e-33 115.5 0.0 4.6e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 EIM84669.1 - 4.3e-30 104.5 0.0 1e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EIM84669.1 - 2.7e-22 78.9 0.0 9.2e-22 77.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EIM84669.1 - 3.6e-11 42.7 2.2 3.6e-11 42.7 2.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EIM84669.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 EIM84669.1 - 0.015 14.9 0.0 0.11 12.1 0.0 2.2 3 0 0 3 3 3 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EIM84669.1 - 0.078 12.8 3.6 0.18 11.7 0.9 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like adh_short PF00106.25 EIM84670.1 - 6.2e-26 91.1 0.1 8.7e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84670.1 - 2e-22 79.9 0.0 2.6e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EIM84670.1 - 2.5e-06 27.5 0.1 2.7e-06 27.4 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM84670.1 - 2e-05 24.6 0.1 2.7e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM84670.1 - 0.0007 19.1 0.0 0.0014 18.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EIM84670.1 - 0.0014 18.9 0.1 0.0022 18.3 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 EIM84670.1 - 0.0015 18.1 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EIM84670.1 - 0.033 13.3 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Lactamase_B_2 PF12706.7 EIM84674.1 - 4.6e-11 42.6 0.2 1.1e-09 38.1 0.2 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM84674.1 - 8.5e-06 25.9 0.1 1.8e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Cu_amine_oxid PF01179.20 EIM84675.1 - 2.9e-127 425.0 6.9 3.8e-127 424.6 6.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EIM84675.1 - 1.6e-23 82.2 1.7 3.6e-23 81.1 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EIM84675.1 - 1.1e-07 32.0 0.0 2.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.24 EIM84676.1 - 4.3e-119 398.3 19.1 5e-119 398.1 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM84676.1 - 3.6e-24 85.4 27.0 3.6e-24 85.4 27.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 EIM84678.1 - 6.7e-18 64.7 7.0 0.00085 20.1 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM84678.1 - 2.2e-06 27.9 0.0 0.21 11.9 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EIM84678.1 - 8.3e-05 22.1 0.0 0.059 12.7 0.0 2.9 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EIM84678.1 - 0.047 13.6 1.0 19 5.3 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat NVEALA PF14055.6 EIM84679.1 - 0.17 11.9 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 NVEALA protein Nop14 PF04147.12 EIM84679.1 - 6.5 4.8 38.0 2 6.5 23.1 2.2 2 0 0 2 2 2 0 Nop14-like family F-box-like PF12937.7 EIM84680.1 - 5.5e-08 32.6 1.1 1.9e-07 30.9 0.6 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM84680.1 - 0.043 14.2 3.6 18 5.9 1.4 5.5 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) DUF4079 PF13301.6 EIM84684.1 - 4.5 7.4 9.8 2.7 8.1 3.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) TatD_DNase PF01026.21 EIM84685.1 - 1.3e-42 146.0 0.0 1.5e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EIM84685.1 - 0.0062 16.4 0.1 0.075 12.8 0.1 2.6 1 1 0 1 1 1 1 Amidohydrolase DUF917 PF06032.12 EIM84685.1 - 0.032 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Zn_clus PF00172.18 EIM84686.1 - 0.00067 19.7 21.5 0.18 11.9 6.3 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain UCR_UQCRX_QCR9 PF05365.12 EIM84687.1 - 0.049 13.6 0.2 0.069 13.1 0.2 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like UCR_UQCRX_QCR9 PF05365.12 EIM84688.1 - 0.057 13.4 0.3 0.08 12.9 0.3 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like ThrE PF06738.12 EIM84691.1 - 6.4e-61 205.8 19.3 1.4e-57 194.9 6.5 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM84691.1 - 3.4e-09 36.9 3.6 3.4e-09 36.9 3.6 2.9 2 1 1 3 3 3 1 Threonine/Serine exporter, ThrE Hydantoinase_B PF02538.14 EIM84692.1 - 3.3e-138 461.3 0.0 4.5e-138 460.9 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EIM84692.1 - 3.6e-91 305.4 1.5 2.9e-90 302.5 0.3 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EIM84692.1 - 3.2e-41 141.0 0.1 9.4e-38 129.7 0.0 3.5 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EIM84692.1 - 0.00031 19.5 0.5 0.57 8.7 0.1 2.3 2 0 0 2 2 2 2 MutL protein Use1 PF09753.9 EIM84694.1 - 0.57 9.9 0.0 0.57 9.9 0.0 2.7 2 1 0 2 2 2 0 Membrane fusion protein Use1 NmrA PF05368.13 EIM84695.1 - 4.1e-21 75.6 0.0 9.5e-21 74.4 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM84695.1 - 7e-14 52.1 0.0 3e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding DapB_N PF01113.20 EIM84695.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EIM84696.1 - 8.8e-22 77.8 0.0 1.8e-21 76.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM84696.1 - 1.7e-11 44.3 0.0 1.1e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EIM84696.1 - 0.0019 18.2 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 EIM84696.1 - 0.043 13.9 0.1 0.14 12.2 0.1 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EIM84696.1 - 0.19 11.2 0.3 0.96 8.9 0.3 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family HMG_box PF00505.19 EIM84697.1 - 4e-12 46.4 0.0 4.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM84697.1 - 0.00088 19.8 0.0 0.001 19.6 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S17e PF00833.18 EIM84697.1 - 0.011 15.6 0.0 0.012 15.5 0.0 1.0 1 0 0 1 1 1 0 Ribosomal S17 UNC-93 PF05978.16 EIM84698.1 - 7e-15 55.1 9.3 7e-15 55.1 9.3 3.0 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EIM84698.1 - 6.1e-14 51.7 47.8 8.4e-14 51.2 44.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily HAMP PF00672.25 EIM84699.1 - 4.9e-41 138.9 10.2 8.3e-08 32.5 0.1 8.1 7 0 0 7 7 7 6 HAMP domain HATPase_c PF02518.26 EIM84699.1 - 4.5e-30 104.4 0.0 1.5e-29 102.7 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM84699.1 - 7e-24 84.2 0.0 8e-23 80.8 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EIM84699.1 - 1.5e-16 60.1 0.8 8.6e-16 57.7 0.8 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4795 PF16043.5 EIM84699.1 - 0.0026 17.4 0.2 10 5.7 0.1 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4795) AcylCoA_dehyd_C PF12186.8 EIM84699.1 - 0.019 15.1 6.5 89 3.3 0.0 5.9 5 1 0 5 5 5 0 Acyl-CoA dehydrogenase C terminal PhaC_N PF07167.13 EIM84699.1 - 0.1 12.2 1.1 13 5.4 0.0 3.6 2 1 1 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Gp-FAR-1 PF05823.12 EIM84699.1 - 0.42 11.0 1.7 26 5.2 0.1 3.9 4 1 1 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF948 PF06103.11 EIM84699.1 - 0.69 10.2 45.2 0.95 9.8 1.4 10.2 5 3 3 8 8 8 0 Bacterial protein of unknown function (DUF948) DUF1843 PF08898.10 EIM84699.1 - 1.3 9.6 9.3 20 5.8 0.1 6.1 6 3 0 6 6 6 0 Domain of unknown function (DUF1843) DUF1664 PF07889.12 EIM84699.1 - 2.6 8.1 26.3 3.7 7.6 0.5 6.2 6 1 0 6 6 6 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EIM84699.1 - 6.8 6.7 14.3 42 4.2 0.4 5.4 5 1 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DNA_binding_1 PF01035.20 EIM84700.1 - 9.6e-14 51.3 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HNH PF01844.23 EIM84701.1 - 0.0036 17.4 2.3 0.024 14.8 2.3 2.3 1 1 0 1 1 1 1 HNH endonuclease C1_1 PF00130.22 EIM84701.1 - 0.028 14.3 0.4 0.083 12.8 0.4 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Solute_trans_a PF03619.16 EIM84702.1 - 3.1e-85 285.9 20.3 3.6e-85 285.7 20.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SelK_SelG PF10961.8 EIM84702.1 - 0.24 12.0 0.4 3.4 8.3 0.1 2.4 1 1 1 2 2 2 0 Selenoprotein SelK_SelG F-box-like PF12937.7 EIM84704.1 - 6.8e-06 25.9 0.9 2e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like Ank_2 PF12796.7 EIM84705.1 - 1.2e-11 45.0 0.0 1.8e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIM84705.1 - 6.5e-09 35.3 0.0 7.6e-05 22.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EIM84705.1 - 7.9e-09 35.9 0.3 0.00018 22.0 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIM84705.1 - 1.4e-08 34.9 0.4 1.2e-05 25.5 0.2 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EIM84705.1 - 5.7e-08 32.9 0.2 3.8e-05 23.9 0.5 2.7 2 0 0 2 2 2 2 Ankyrin repeat PLDc PF00614.22 EIM84706.1 - 5.6e-16 58.0 6.9 1.5e-08 34.5 0.2 2.9 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EIM84706.1 - 1.9e-13 50.4 0.0 3.4e-07 30.2 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain F-box-like PF12937.7 EIM84707.1 - 6.2e-09 35.6 3.9 3.3e-08 33.3 0.3 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM84707.1 - 0.016 15.1 4.0 0.4 10.6 0.0 3.4 3 0 0 3 3 3 0 F-box domain HECT PF00632.25 EIM84708.1 - 3.6e-95 319.0 0.0 4.7e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EIM84708.1 - 6.3e-36 122.1 15.4 1.4e-11 44.3 0.3 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EIM84708.1 - 4e-20 72.0 0.2 8.9e-20 70.9 0.2 1.6 1 0 0 1 1 1 1 C2 domain F-box-like PF12937.7 EIM84709.1 - 9.4e-08 31.8 0.1 2.1e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_9 PF14580.6 EIM84709.1 - 0.21 11.1 5.8 4.5 6.7 0.1 3.2 3 0 0 3 3 3 0 Leucine-rich repeat LRR_4 PF12799.7 EIM84709.1 - 0.99 9.9 7.3 35 5.0 0.0 5.3 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) DUF4448 PF14610.6 EIM84710.1 - 6.4e-08 32.6 0.1 1.1e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 EIM84710.1 - 0.046 14.5 2.6 0.23 12.2 1.8 2.4 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family VSP PF03302.13 EIM84710.1 - 0.059 12.2 0.2 0.097 11.5 0.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein FmdA_AmdA PF03069.15 EIM84712.1 - 1.6e-61 208.3 0.0 9e-37 126.8 0.1 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family Nup84_Nup100 PF04121.13 EIM84713.1 - 1.2e-145 486.6 0.0 1.5e-145 486.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 CSTF2_hinge PF14327.6 EIM84713.1 - 0.055 13.9 2.2 31 5.1 0.0 4.2 4 0 0 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 Abhydrolase_1 PF00561.20 EIM84714.1 - 2.1e-07 30.9 0.0 5.9e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM84714.1 - 3.5e-05 24.5 0.0 4.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM84714.1 - 0.00017 20.9 0.0 0.0076 15.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EIM84714.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EIM84714.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EIM84715.1 - 8.2e-11 42.0 0.0 1.5e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM84715.1 - 1.5e-06 27.7 0.0 0.004 16.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM84715.1 - 6.9e-06 26.8 0.0 1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIM84715.1 - 0.00013 21.5 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EIM84715.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EIM84715.1 - 0.042 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Cyclase PF04199.13 EIM84716.1 - 1.3e-34 119.4 0.1 1.4e-34 119.2 0.1 1.0 1 0 0 1 1 1 1 Putative cyclase PyrI_C PF02748.15 EIM84717.1 - 0.043 13.7 0.2 0.074 13.0 0.2 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FAD_binding_4 PF01565.23 EIM84718.1 - 1.4e-27 96.2 8.2 2.1e-27 95.6 6.9 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EIM84718.1 - 5.3e-06 26.4 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like MutL_C PF08676.11 EIM84719.1 - 0.025 14.4 0.3 0.048 13.4 0.3 1.4 1 0 0 1 1 1 0 MutL C terminal dimerisation domain zf-RING_2 PF13639.6 EIM84720.1 - 5.8e-08 32.9 13.2 9.8e-08 32.2 13.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM84720.1 - 9.4e-07 28.6 12.0 1.6e-06 27.9 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM84720.1 - 3.9e-06 27.1 8.8 7.8e-06 26.1 8.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EIM84720.1 - 8.2e-06 25.6 12.2 1.3e-05 24.9 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM84720.1 - 0.00024 20.9 14.1 0.00036 20.3 14.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM84720.1 - 0.0047 16.6 5.7 0.0091 15.7 5.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EIM84720.1 - 0.0091 16.0 8.9 0.019 15.0 8.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM84720.1 - 0.19 11.9 10.3 0.41 10.9 10.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EIM84720.1 - 2.1 8.4 15.1 3.6 7.6 15.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Homeodomain PF00046.29 EIM84721.1 - 8.3e-15 54.4 1.1 1.6e-14 53.5 1.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EIM84721.1 - 0.026 14.4 1.4 0.055 13.4 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain SPC12 PF06645.13 EIM84722.1 - 2.4e-25 88.4 0.1 2.8e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) BTB PF00651.31 EIM84725.1 - 3.3e-07 30.5 0.0 5.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Bromodomain PF00439.25 EIM84726.1 - 3.3e-18 65.5 0.0 7.3e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain MCD_N PF17408.2 EIM84726.1 - 0.031 14.4 0.3 0.084 13.0 0.3 1.7 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain RicinB_lectin_2 PF14200.6 EIM84727.1 - 2.6e-18 66.5 0.9 4.5e-12 46.5 0.1 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EIM84727.1 - 7.6e-05 23.0 0.0 1.2 9.4 0.0 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIM84729.1 - 5.7e-09 36.6 0.3 4.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EIM84729.1 - 0.041 14.1 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Chromo PF00385.24 EIM84729.1 - 0.053 13.4 0.2 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain RicinB_lectin_2 PF14200.6 EIM84730.1 - 2.9e-07 31.1 0.2 3.2e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF455 PF04305.14 EIM84731.1 - 3.2e-95 318.4 0.1 4.5e-95 317.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 EIM84731.1 - 2.5e-07 30.5 0.1 8.1e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EIM84731.1 - 0.00011 22.1 0.0 0.00036 20.4 0.0 1.9 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain TauD PF02668.16 EIM84732.1 - 6.4e-45 154.0 0.0 7.9e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DNA_mis_repair PF01119.19 EIM84733.1 - 1.3e-19 70.0 0.0 4.6e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EIM84733.1 - 6.8e-19 68.1 0.9 1.7e-14 53.8 0.5 2.9 2 1 0 2 2 2 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EIM84733.1 - 1.1e-12 48.0 0.1 3.5e-12 46.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EIM84733.1 - 4.3e-09 36.9 0.1 2.8e-08 34.3 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hva1_TUDOR PF11160.8 EIM84734.1 - 2.7e-17 62.6 3.0 3.2e-17 62.4 3.0 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Pkinase_fungal PF17667.1 EIM84736.1 - 1.2e-73 248.3 0.0 1.1e-36 126.5 0.0 3.9 3 1 0 3 3 3 3 Fungal protein kinase Pkinase PF00069.25 EIM84736.1 - 4.6e-16 59.0 0.0 1.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 EIM84736.1 - 2e-07 30.8 1.8 0.0086 15.7 0.0 2.8 2 1 0 2 2 2 2 RIO1 family APH PF01636.23 EIM84736.1 - 3.7e-07 30.3 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM84736.1 - 0.12 11.3 0.0 9.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Ubiquitin_4 PF18036.1 EIM84736.1 - 0.4 10.8 3.2 10 6.3 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-like domain Pkinase_fungal PF17667.1 EIM84737.1 - 3.4e-37 128.2 0.0 5.7e-36 124.2 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EIM84737.1 - 2.3e-05 23.9 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM84737.1 - 0.0039 17.2 0.2 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM84737.1 - 0.0083 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family NiFe-hyd_HybE PF11939.8 EIM84737.1 - 0.023 14.6 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE Haspin_kinase PF12330.8 EIM84737.1 - 0.044 12.7 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 EIM84737.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_transf_15 PF01793.16 EIM84738.1 - 3.5e-123 411.0 9.9 4.3e-123 410.7 9.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Fic PF02661.18 EIM84739.1 - 2.4e-08 34.8 0.0 4.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family Peptidase_S64 PF08192.11 EIM84740.1 - 0.035 12.6 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Sec7_N PF12783.7 EIM84741.1 - 5e-52 176.0 0.1 1.4e-50 171.3 0.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EIM84741.1 - 7.7e-38 129.9 1.4 1.9e-37 128.7 1.4 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EIM84741.1 - 1.9e-37 128.9 1.5 1.9e-23 82.6 0.1 3.6 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 EIM84741.1 - 3.5e-05 23.6 0.0 0.00025 20.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 EIM84741.1 - 0.11 12.7 0.2 5.6 7.2 0.0 3.5 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EIM84741.1 - 0.57 10.6 2.6 5.4 7.5 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Pkinase_fungal PF17667.1 EIM84742.1 - 6.1e-42 143.8 0.0 1.1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EIM84742.1 - 6.3e-06 25.7 0.1 1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIM84742.1 - 0.0017 18.0 0.1 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM84742.1 - 0.0098 15.8 0.7 0.017 15.0 0.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM84742.1 - 0.057 12.4 0.1 0.087 11.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 EIM84742.1 - 0.17 11.1 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM84743.1 - 5.3e-47 160.5 0.0 1.4e-37 129.5 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM84743.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM84743.1 - 0.0035 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM84743.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EIM84745.1 - 1.4e-63 214.8 0.1 3.1e-62 210.3 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM84745.1 - 4e-36 124.6 0.0 8.2e-36 123.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EIM84745.1 - 1.2e-17 63.4 0.1 2.1e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EIM84745.1 - 2.2e-06 27.2 0.1 3.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM84745.1 - 0.00029 20.2 0.0 0.00062 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM84745.1 - 0.00034 20.6 0.0 0.0014 18.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM84745.1 - 0.00074 18.6 0.2 0.0015 17.6 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 EIM84745.1 - 0.032 13.8 0.2 0.052 13.2 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RFXA_RFXANK_bdg PF15289.6 EIM84745.1 - 0.25 11.7 5.0 0.66 10.3 5.0 1.7 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Spt20 PF12090.8 EIM84745.1 - 1.6 8.3 12.5 5.5 6.5 12.5 1.8 1 0 0 1 1 1 0 Spt20 family Pkinase_fungal PF17667.1 EIM84746.1 - 8.2e-11 41.3 6.2 2.2e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase DUF4685 PF15737.5 EIM84746.1 - 0.059 13.8 3.8 1.3 9.5 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Pkinase_fungal PF17667.1 EIM84747.1 - 1.2e-29 103.4 0.0 6e-29 101.0 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EIM84747.1 - 3.8e-05 23.2 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIM84747.1 - 0.0025 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM84747.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM84748.1 - 3.6e-50 170.9 0.0 3.8e-37 128.1 0.0 2.7 2 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM84748.1 - 1.3e-07 31.3 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM84748.1 - 0.00033 20.7 0.1 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM84748.1 - 0.00073 19.2 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Rad60-SLD PF11976.8 EIM84749.1 - 5.9e-23 80.5 0.4 8.1e-23 80.0 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EIM84749.1 - 4.3e-13 48.8 0.5 5e-13 48.6 0.1 1.3 2 0 0 2 2 2 1 Ubiquitin family Cadherin-like PF12733.7 EIM84749.1 - 0.018 15.6 2.5 5.5 7.6 0.2 2.9 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain DUF4140 PF13600.6 EIM84751.1 - 0.0082 16.6 0.3 0.023 15.2 0.1 1.7 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) TACC_C PF05010.14 EIM84751.1 - 0.16 11.7 1.8 1.1 9.0 0.1 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HrpB7 PF09486.10 EIM84751.1 - 0.32 11.4 7.5 2.1 8.7 0.6 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) SNF2_N PF00176.23 EIM84752.1 - 5e-63 212.9 0.2 7.2e-62 209.1 0.1 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM84752.1 - 1.6e-17 63.8 0.0 6.6e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM84752.1 - 5e-08 33.1 0.2 0.0022 18.0 0.0 3.5 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIM84752.1 - 0.0023 17.2 0.0 0.049 12.8 0.0 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ITAM PF02189.15 EIM84752.1 - 0.069 13.6 1.0 0.67 10.5 0.0 2.6 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif TMEM154 PF15102.6 EIM84753.1 - 0.00098 19.0 0.6 0.00098 19.0 0.6 3.1 3 1 1 4 4 4 1 TMEM154 protein family PD40 PF07676.12 EIM84755.1 - 1.1e-32 111.2 22.7 4.2e-09 36.1 1.1 9.1 9 0 0 9 9 9 6 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EIM84755.1 - 0.00036 19.4 13.6 2.9 6.6 0.0 6.7 4 2 2 6 6 6 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 EIM84755.1 - 0.065 13.2 2.1 25 4.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3748) WD40 PF00400.32 EIM84755.1 - 2.4 9.2 12.6 36 5.4 0.1 5.7 5 1 0 5 5 5 0 WD domain, G-beta repeat Aa_trans PF01490.18 EIM84756.1 - 5.9e-33 114.2 38.9 6.9e-33 113.9 38.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase_fungal PF17667.1 EIM84757.1 - 1.9e-51 175.1 0.0 3.2e-37 128.3 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM84757.1 - 8.1e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM84757.1 - 0.00049 20.1 0.1 0.00094 19.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM84757.1 - 0.0033 17.0 0.1 0.0082 15.8 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EIM84757.1 - 0.058 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EIM84758.1 - 6.3e-29 101.0 0.0 3.4e-25 88.7 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM84758.1 - 1.6e-05 24.5 0.0 4.4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EIM84758.1 - 0.0025 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM84758.1 - 0.0099 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM84759.1 - 1.7e-36 125.9 0.0 2.4e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EIM84759.1 - 2.3e-06 27.2 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM84759.1 - 4.3e-05 23.6 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM84759.1 - 0.00035 20.2 0.0 0.00079 19.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EIM84759.1 - 0.007 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain GST_N_3 PF13417.6 EIM84761.1 - 2.8e-09 37.3 0.1 5.7e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM84761.1 - 0.00054 20.2 0.0 0.00098 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cpn10 PF00166.21 EIM84761.1 - 0.029 14.4 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit DUF5599 PF18141.1 EIM84761.1 - 0.16 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) F-box-like PF12937.7 EIM84762.1 - 9.4e-08 31.8 0.9 9.4e-08 31.8 0.9 2.4 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 EIM84763.1 - 2.7e-11 43.2 0.5 8.8e-11 41.5 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM84763.1 - 0.03 14.2 5.7 0.28 11.1 5.7 2.4 1 1 0 1 1 1 0 F-box domain 2OG-FeII_Oxy_2 PF13532.6 EIM84764.1 - 1.1e-25 91.0 0.0 1.6e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 EIM84765.1 - 4.4e-06 26.5 0.1 1.3e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM84765.1 - 0.01 15.7 0.0 0.036 13.9 0.0 1.9 1 0 0 1 1 1 0 F-box domain SnoaL_2 PF12680.7 EIM84766.1 - 1.7e-05 25.4 0.1 2.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EIM84766.1 - 0.00034 20.7 0.1 0.00049 20.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EIM84766.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Phosphodiest PF01663.22 EIM84767.1 - 3e-11 43.5 1.1 4.7e-11 42.9 0.7 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EIM84767.1 - 0.004 16.6 0.4 0.0069 15.8 0.4 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily CcmD PF04995.14 EIM84767.1 - 0.0096 16.0 0.4 0.036 14.1 0.2 2.1 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) Sulfatase PF00884.23 EIM84767.1 - 0.022 14.2 0.3 0.022 14.2 0.3 1.9 2 1 0 3 3 3 0 Sulfatase GspL_C PF12693.7 EIM84767.1 - 3.3 7.5 4.7 40 4.0 0.0 2.4 2 0 0 2 2 2 0 GspL periplasmic domain cNMP_binding PF00027.29 EIM84768.1 - 8.5e-33 112.3 0.5 3.6e-13 49.4 0.1 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RIIa PF02197.17 EIM84768.1 - 2.7e-08 33.4 0.3 3.8e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit AAA PF00004.29 EIM84770.1 - 9.2e-19 68.2 0.0 2.5e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM84770.1 - 0.0079 16.6 0.1 0.5 10.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EIM84770.1 - 0.015 15.3 0.1 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EIM84770.1 - 0.061 13.1 0.5 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EIM84770.1 - 0.095 13.0 0.0 0.53 10.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain Topoisom_I_N PF02919.15 EIM84770.1 - 0.26 10.8 3.3 0.51 9.8 3.3 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment AAA PF00004.29 EIM84771.1 - 9e-19 68.2 0.0 3.3e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM84771.1 - 0.0049 17.3 0.1 0.51 10.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM84771.1 - 0.021 15.1 0.0 0.52 10.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EIM84771.1 - 0.022 14.8 0.0 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EIM84771.1 - 0.044 13.3 0.0 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 EIM84771.1 - 0.1 12.4 0.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIM84771.1 - 0.11 12.3 0.2 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EIM84771.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EIM84771.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 EIM84771.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EIM84771.1 - 0.18 12.4 0.1 0.41 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Prenyltrans PF00432.21 EIM84772.1 - 1e-57 191.5 7.1 2.5e-12 46.3 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EIM84772.1 - 0.0019 17.4 0.0 0.0041 16.3 0.0 1.5 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EIM84772.1 - 0.002 17.3 0.0 0.16 11.0 0.0 3.2 2 1 2 4 4 4 1 Squalene-hopene cyclase N-terminal domain Rop PF01815.16 EIM84772.1 - 0.13 12.1 0.9 3.8 7.5 0.0 3.2 4 0 0 4 4 4 0 Rop protein ITAM_Cys-rich PF10538.9 EIM84774.1 - 0.31 10.8 1.4 0.8 9.5 1.4 1.7 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif Asp PF00026.23 EIM84778.1 - 0.0021 17.5 0.0 0.68 9.3 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EIM84778.1 - 0.0051 17.4 0.0 9.5 6.9 0.0 3.8 4 0 0 4 4 4 1 Aspartyl protease TAXi_N PF14543.6 EIM84778.1 - 0.019 15.2 0.1 3.5 7.8 0.0 2.9 3 1 0 3 3 3 0 Xylanase inhibitor N-terminal Rhodanese PF00581.20 EIM84781.1 - 5.1e-07 30.2 0.0 9.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Atg29_N PF18388.1 EIM84781.1 - 0.13 12.1 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 Atg29 N-terminal domain Alpha_L_fucos PF01120.17 EIM84783.1 - 2.5e-77 260.7 0.8 3.2e-76 257.1 0.8 2.0 1 1 0 1 1 1 1 Alpha-L-fucosidase ZirS_C PF16583.5 EIM84783.1 - 0.13 11.8 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Fungal_trans PF04082.18 EIM84785.1 - 3.3e-14 52.6 0.4 8.6e-14 51.2 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM84785.1 - 0.00019 21.5 11.1 0.0003 20.8 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_2 PF12680.7 EIM84786.1 - 0.0016 19.0 0.0 0.002 18.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EIM84786.1 - 0.067 13.8 0.0 0.082 13.5 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain FGGY_N PF00370.21 EIM84787.1 - 8.5e-05 22.2 0.0 0.0028 17.2 0.0 2.1 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain F-box PF00646.33 EIM84789.1 - 3e-07 30.2 0.3 8.8e-07 28.7 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM84789.1 - 0.0011 18.8 0.2 0.004 17.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EIM84789.1 - 0.0062 16.4 0.3 0.013 15.4 0.3 1.5 1 0 0 1 1 1 1 F-box GMC_oxred_C PF05199.13 EIM84790.1 - 4.6e-33 114.8 0.0 7.4e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EIM84791.1 - 5.2e-27 95.0 0.0 5.6e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase DUF1348 PF07080.11 EIM84793.1 - 2e-65 218.6 6.8 2.3e-65 218.4 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EIM84793.1 - 3.7e-06 27.5 0.1 4.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EIM84793.1 - 0.05 14.0 0.0 0.09 13.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) MFS_1 PF07690.16 EIM84794.1 - 2.8e-34 118.6 29.9 2.8e-34 118.6 29.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 EIM84794.1 - 2.5 6.3 23.4 0.18 10.1 9.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Epimerase PF01370.21 EIM84795.1 - 7.5e-17 61.6 0.1 3.5e-16 59.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EIM84795.1 - 4.4e-14 52.3 0.0 2.3e-08 33.6 0.0 2.9 3 1 0 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 EIM84795.1 - 6.1e-13 48.4 0.0 2.4e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM84795.1 - 8.3e-08 32.0 0.2 4.2e-07 29.7 0.0 2.1 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM84795.1 - 9.3e-08 32.2 0.4 1.6e-07 31.4 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM84795.1 - 0.00024 20.8 0.2 0.00035 20.2 0.2 1.4 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EIM84795.1 - 0.0038 16.4 0.0 0.72 8.9 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 EIM84795.1 - 0.0049 16.4 0.7 0.027 13.9 0.4 2.4 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM84795.1 - 0.13 11.4 1.4 0.92 8.6 1.2 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein RPE65 PF03055.15 EIM84795.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein ABM PF03992.16 EIM84796.1 - 1.1e-09 38.3 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 EIM84797.1 - 1.6e-09 37.8 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FMO-like PF00743.19 EIM84798.1 - 1.3e-14 53.5 0.5 9.9e-10 37.4 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM84798.1 - 4.1e-11 42.7 0.0 1.7e-06 27.5 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM84798.1 - 2.1e-10 40.4 0.6 0.00078 18.8 0.1 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM84798.1 - 2.8e-09 36.6 0.2 2e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EIM84798.1 - 6.1e-05 21.9 0.6 0.0012 17.7 0.7 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EIM84798.1 - 0.00049 19.5 0.3 0.00082 18.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EIM84798.1 - 0.0011 18.1 0.6 0.053 12.6 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EIM84798.1 - 0.0046 17.0 0.2 1.1 9.3 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIM84798.1 - 0.01 14.9 1.7 0.012 14.7 0.6 1.6 2 0 0 2 2 2 0 FAD binding domain THF_DHG_CYH_C PF02882.19 EIM84798.1 - 0.015 14.6 0.1 0.29 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GIDA PF01134.22 EIM84798.1 - 0.016 14.4 0.2 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM84798.1 - 0.019 15.2 0.5 0.049 13.9 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF498 PF04430.14 EIM84798.1 - 0.053 13.6 0.1 0.65 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) Thi4 PF01946.17 EIM84798.1 - 0.063 12.5 0.4 0.72 9.1 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EIM84798.1 - 0.12 12.9 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EIM84798.1 - 0.25 11.4 1.0 5.9 7.0 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IBR PF01485.21 EIM84799.1 - 1.8e-12 47.3 28.2 2.4e-09 37.3 6.9 4.4 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain NUDIX_2 PF13869.6 EIM84800.1 - 4e-84 280.9 0.0 4.5e-84 280.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M36 PF02128.15 EIM84801.1 - 1.7e-158 527.7 1.1 2.2e-158 527.3 1.1 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EIM84801.1 - 2.6e-14 52.8 1.3 4.8e-14 51.9 1.3 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EIM84801.1 - 0.078 12.8 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Ras PF00071.22 EIM84802.1 - 1.1e-55 187.6 0.1 2.1e-55 186.8 0.0 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EIM84802.1 - 1.1e-33 116.0 0.1 8.8e-33 113.1 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM84802.1 - 5.4e-15 55.3 0.0 6.7e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM84802.1 - 1.4e-06 28.4 0.0 3.2e-06 27.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIM84802.1 - 1.6e-06 27.7 0.0 1.9e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIM84802.1 - 0.0011 18.6 0.0 0.0026 17.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EIM84802.1 - 0.0065 16.9 0.0 0.02 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EIM84802.1 - 0.031 14.2 0.2 0.58 10.0 0.0 2.2 1 1 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EIM84802.1 - 0.043 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EIM84802.1 - 0.052 12.7 1.0 2.3 7.3 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.18 EIM84802.1 - 0.056 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 EIM84802.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 EIM84802.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Epimerase PF01370.21 EIM84803.1 - 4.2e-18 65.7 0.1 1.7e-17 63.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM84803.1 - 1.7e-14 53.5 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM84803.1 - 1.1e-12 47.7 0.0 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EIM84803.1 - 7.8e-12 45.4 0.1 1.1e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIM84803.1 - 5.6e-10 39.1 0.0 2.1e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EIM84803.1 - 1.5e-05 24.6 0.5 2.7e-05 23.8 0.5 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EIM84803.1 - 0.0014 17.7 0.0 0.48 9.5 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 EIM84803.1 - 0.0018 17.8 0.1 0.47 9.9 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM84803.1 - 0.002 17.3 0.0 0.016 14.4 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EIM84803.1 - 0.13 12.2 0.1 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 KR domain F-box-like PF12937.7 EIM84804.1 - 7.6e-08 32.1 0.3 7.6e-08 32.1 0.3 2.0 2 0 0 2 2 2 1 F-box-like PARP PF00644.20 EIM84805.1 - 1.1e-15 57.8 2.3 1.1e-11 44.7 0.2 2.9 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain RMP PF14996.6 EIM84805.1 - 0.014 15.7 0.3 0.02 15.1 0.3 1.2 1 0 0 1 1 1 0 Retinal Maintenance TMEM52 PF14979.6 EIM84806.1 - 0.046 13.6 0.2 0.057 13.3 0.2 1.2 1 0 0 1 1 1 0 Transmembrane 52 Dak1_2 PF13684.6 EIM84806.1 - 0.067 12.3 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Sulfate_transp PF00916.20 EIM84807.1 - 3.6e-60 203.7 19.8 3.6e-60 203.7 19.8 1.7 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 EIM84807.1 - 3.7e-13 49.4 0.0 8.9e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EIM84807.1 - 7.3e-10 38.5 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EIM84807.1 - 0.013 15.9 2.1 0.013 15.9 2.1 3.8 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF5504 PF17608.2 EIM84807.1 - 0.069 13.3 2.4 0.21 11.7 2.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5504) UCR_UQCRX_QCR9 PF05365.12 EIM84807.1 - 0.11 12.4 0.0 0.53 10.3 0.0 2.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like F-box-like PF12937.7 EIM84810.1 - 5.2e-07 29.5 0.4 1.4e-06 28.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM84810.1 - 0.017 15.0 0.6 0.05 13.5 0.6 1.7 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 EIM84810.1 - 0.045 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 F-box Zip PF02535.22 EIM84811.1 - 6.2e-49 167.0 18.4 4.8e-47 160.8 18.4 2.9 1 1 0 1 1 1 1 ZIP Zinc transporter CbiQ PF02361.16 EIM84811.1 - 0.88 9.1 0.0 0.88 9.1 0.0 2.6 2 1 1 3 3 3 0 Cobalt transport protein Inhibitor_I9 PF05922.16 EIM84812.1 - 1.6e-05 25.5 0.0 2.8e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 OCD_Mu_crystall PF02423.15 EIM84813.1 - 2.7e-24 85.7 7.7 2.2e-12 46.6 1.7 2.9 1 1 1 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EIM84813.1 - 2.7e-07 30.7 0.1 0.0058 16.7 0.1 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Oxidored_FMN PF00724.20 EIM84814.1 - 2.1e-88 296.9 0.0 1.1e-87 294.5 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Gp45_2 PF17470.2 EIM84814.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage gene product 45.2 Oxidored_FMN PF00724.20 EIM84815.1 - 1.1e-96 324.1 0.0 1.3e-96 323.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family zf-MYND PF01753.18 EIM84816.1 - 2e-11 43.8 11.0 4.1e-11 42.8 11.0 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM84816.1 - 0.0013 19.0 4.3 0.0037 17.5 4.3 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Reo_sigmaC PF04582.12 EIM84816.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain PGA2 PF07543.12 EIM84816.1 - 0.47 10.4 5.4 1 9.3 5.4 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 TFIIF_alpha PF05793.12 EIM84816.1 - 6.7 5.2 19.9 10 4.5 19.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 EIM84816.1 - 9.7 5.4 14.1 16 4.7 14.1 1.4 1 0 0 1 1 1 0 BUD22 Diphthamide_syn PF01866.17 EIM84817.1 - 1.4e-101 339.9 0.1 2.2e-101 339.3 0.1 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_1 PF00515.28 EIM84818.1 - 1.3e-40 135.5 1.7 0.00026 20.7 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EIM84818.1 - 1.9e-32 108.7 8.8 0.0067 16.5 0.0 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 EIM84818.1 - 1.9e-22 77.5 2.4 0.37 11.1 0.0 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 EIM84818.1 - 6.1e-20 71.6 5.7 1.7e-05 25.4 0.1 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EIM84818.1 - 1.1e-18 66.4 5.8 0.029 15.2 0.0 8.2 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EIM84818.1 - 1.9e-18 65.8 5.3 0.0035 17.0 0.0 8.9 7 2 2 9 9 9 4 TPR repeat TPR_19 PF14559.6 EIM84818.1 - 5.9e-18 65.1 12.6 3.3e-05 24.3 0.6 6.6 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EIM84818.1 - 1.6e-17 63.6 17.0 0.0027 18.0 0.0 8.9 4 2 5 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 EIM84818.1 - 3.5e-14 52.1 7.4 0.01 16.2 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EIM84818.1 - 1.6e-13 50.6 2.0 0.0044 17.1 1.0 5.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIM84818.1 - 9.6e-10 37.8 8.6 0.86 9.8 0.0 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM84818.1 - 3.7e-08 33.5 2.9 0.066 13.4 0.4 5.2 3 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EIM84818.1 - 9e-07 28.6 6.0 1.2e-06 28.1 2.3 2.9 2 1 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 EIM84818.1 - 3e-06 27.5 10.8 0.77 10.5 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 EIM84818.1 - 0.00011 22.3 0.5 1.4 9.0 0.0 5.1 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 EIM84818.1 - 0.00041 20.1 7.7 11 5.7 0.2 5.4 4 1 2 6 6 5 0 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 EIM84818.1 - 0.0014 18.0 6.7 3.7 7.1 0.0 5.2 6 0 0 6 6 6 2 SHNi-TPR TPR_10 PF13374.6 EIM84818.1 - 0.018 14.9 17.2 21 5.1 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM84818.1 - 0.04 14.0 2.9 3.7 7.7 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EIM84818.1 - 0.054 13.9 6.7 3.4 8.1 1.3 3.6 3 1 1 4 4 3 0 Bacterial transcriptional activator domain NARP1 PF12569.8 EIM84818.1 - 0.27 10.1 11.5 1.3 7.8 0.0 3.6 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 EIM84818.1 - 0.46 11.3 3.2 22 6.1 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat MIT PF04212.18 EIM84818.1 - 9.5 6.4 12.2 48 4.1 0.1 5.4 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain zf-MYND PF01753.18 EIM84819.1 - 1.4e-11 44.2 12.2 4.1e-11 42.8 12.2 1.8 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM84819.1 - 0.017 15.4 4.2 0.034 14.4 4.2 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PAP2_3 PF14378.6 EIM84820.1 - 6.7e-25 87.9 16.2 1.5e-24 86.7 16.2 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 EIM84820.1 - 1.7e-09 37.6 6.3 1.7e-09 37.6 6.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily MFS_1 PF07690.16 EIM84821.1 - 4.6e-30 104.7 36.7 6.2e-30 104.3 36.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtB PF09489.10 EIM84821.1 - 0.97 9.6 5.1 0.37 10.9 1.2 2.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF2070 PF09843.9 EIM84821.1 - 9.5 4.4 23.1 0.49 8.6 8.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) polyprenyl_synt PF00348.17 EIM84825.1 - 4e-56 189.9 0.0 4.9e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.22 EIM84826.1 - 7.2e-51 173.4 0.0 9.1e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UDPGT PF00201.18 EIM84827.1 - 3e-18 65.9 0.0 4.5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase p450 PF00067.22 EIM84828.1 - 5.8e-68 229.7 0.0 3.9e-67 227.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.28 EIM84829.1 - 2.8e-22 78.7 1.3 2.2e-20 72.6 0.1 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EIM84829.1 - 1.2e-12 48.3 15.1 1.2e-12 48.3 15.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FMO-like PF00743.19 EIM84831.1 - 9.2e-14 50.7 0.0 9.2e-07 27.7 0.0 3.1 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM84831.1 - 6.3e-09 35.5 0.0 0.0058 15.9 0.0 3.4 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM84831.1 - 8.6e-09 35.5 0.7 1.8e-07 31.2 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EIM84831.1 - 9.9e-06 24.9 0.0 0.00082 18.6 0.0 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EIM84831.1 - 1.4e-05 24.5 0.4 0.1 11.9 0.1 3.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM84831.1 - 1.6e-05 25.3 0.8 0.21 12.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EIM84831.1 - 0.00015 21.2 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EIM84831.1 - 0.0002 20.7 0.2 0.27 10.5 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EIM84831.1 - 0.00045 20.2 0.1 0.028 14.4 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 EIM84831.1 - 0.0006 19.5 0.1 0.0006 19.5 0.1 2.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM84831.1 - 0.0022 17.3 0.4 0.065 12.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EIM84831.1 - 0.0026 17.2 0.4 0.39 10.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM84831.1 - 0.0077 15.0 2.2 0.51 9.0 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EIM84831.1 - 0.01 14.9 3.2 0.2 10.7 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EIM84831.1 - 0.012 14.7 1.9 2.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EIM84831.1 - 0.016 15.1 1.4 0.025 14.4 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EIM84831.1 - 0.042 13.9 0.0 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EIM84831.1 - 0.05 14.0 0.2 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EIM84831.1 - 0.055 12.8 0.1 0.77 9.1 0.0 2.5 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Piwi PF02171.17 EIM84832.1 - 7.8e-76 255.2 0.0 1.1e-75 254.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EIM84832.1 - 1.4e-15 58.1 0.1 3.8e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 EIM84832.1 - 3.8e-13 49.4 0.0 7.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EIM84832.1 - 1.6e-11 43.7 0.0 8.7e-11 41.3 0.0 2.4 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EIM84832.1 - 3.4e-11 43.3 0.1 9.3e-11 41.9 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EIM84832.1 - 0.0086 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute p450 PF00067.22 EIM84833.1 - 6.3e-65 219.7 0.0 7.8e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EOS1 PF12326.8 EIM84834.1 - 9e-34 116.9 16.1 6.1e-29 101.2 12.5 2.5 2 0 0 2 2 2 2 N-glycosylation protein ABM PF03992.16 EIM84835.1 - 7.6e-08 32.4 0.0 8.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Med25_VWA PF11265.8 EIM84836.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Epimerase PF01370.21 EIM84838.1 - 9.6e-18 64.5 0.0 1.9e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM84838.1 - 2.9e-14 52.7 0.0 5.6e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM84838.1 - 6.4e-14 52.3 0.0 1.5e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM84838.1 - 9.8e-08 31.5 0.0 1.1e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIM84838.1 - 8.6e-06 25.4 0.0 4.3e-05 23.1 0.1 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EIM84838.1 - 6e-05 22.7 0.1 0.002 17.7 0.3 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EIM84838.1 - 0.00081 18.9 0.2 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM84838.1 - 0.0073 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.21 EIM84840.1 - 1.3e-72 244.5 0.0 1.5e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Yae1_N PF09811.9 EIM84841.1 - 1.8e-10 40.3 2.2 3.4e-10 39.4 2.2 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.22 EIM84842.1 - 0.0001 22.6 0.0 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain DUF3638 PF12340.8 EIM84843.1 - 1.8e-88 295.7 0.6 3.9e-88 294.6 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EIM84843.1 - 1.2e-17 62.9 0.1 2.6e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Proteasome PF00227.26 EIM84843.1 - 0.18 11.3 0.1 0.72 9.3 0.1 2.0 1 0 0 1 1 1 0 Proteasome subunit Cu_amine_oxid PF01179.20 EIM84844.1 - 1.8e-153 511.3 0.0 2.4e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EIM84844.1 - 2.6e-13 50.2 0.0 5.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EIM84844.1 - 0.00012 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hydro_18 PF00704.28 EIM84845.1 - 1.2e-12 48.3 0.9 1.4e-12 48.0 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Rad60-SLD PF11976.8 EIM84846.1 - 3.3e-06 26.9 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EIM84846.1 - 0.00026 20.7 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF523 PF04463.12 EIM84846.1 - 0.015 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF523) TUG-UBL1 PF11470.8 EIM84846.1 - 0.03 14.6 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain Rad60-SLD PF11976.8 EIM84847.1 - 1.6e-11 43.9 0.0 2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EIM84847.1 - 5.9e-05 22.8 0.0 7.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 EIM84847.1 - 0.0061 16.8 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 TUG ubiquitin-like domain Alba PF01918.21 EIM84847.1 - 0.089 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Alba PB1 PF00564.24 EIM84847.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 PB1 domain Methyltransf_16 PF10294.9 EIM84848.1 - 7.5e-29 100.7 0.0 2.1e-28 99.2 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EIM84848.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM84848.1 - 0.012 15.5 0.0 0.041 13.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 EIM84849.1 - 4.9e-94 315.4 0.1 6.1e-94 315.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM84849.1 - 1e-22 80.9 0.0 2.2e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EIM84849.1 - 5.8e-07 28.6 1.0 8.5e-07 28.0 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM84849.1 - 1.9e-06 27.4 0.9 5.9e-06 25.7 0.6 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM84849.1 - 4.3e-06 27.2 0.2 0.0001 22.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM84849.1 - 0.00011 22.4 0.1 0.00027 21.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM84849.1 - 0.00023 20.4 0.4 0.00044 19.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EIM84849.1 - 0.001 18.3 0.4 0.002 17.3 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EIM84849.1 - 0.001 18.7 2.0 0.015 14.9 0.4 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM84849.1 - 0.0016 17.6 1.3 0.0027 16.8 0.6 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EIM84849.1 - 0.0023 17.4 1.0 0.0039 16.6 1.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EIM84849.1 - 0.0029 16.9 0.1 0.0044 16.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EIM84849.1 - 0.0031 16.8 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EIM84849.1 - 0.0037 16.6 0.3 0.0064 15.8 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EIM84849.1 - 0.0037 17.2 0.1 0.0068 16.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EIM84849.1 - 0.0056 16.9 0.1 0.014 15.6 0.1 1.7 2 0 0 2 2 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EIM84849.1 - 0.0074 15.9 0.3 0.015 14.9 0.3 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.10 EIM84849.1 - 0.033 13.2 0.0 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 EIM84849.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EIM84849.1 - 0.13 12.7 0.1 0.53 10.7 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding TFIIS_M PF07500.14 EIM84851.1 - 2.9e-34 117.9 0.3 2.9e-34 117.9 0.3 2.7 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EIM84851.1 - 7.1e-17 61.0 10.9 1.2e-16 60.2 10.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EIM84851.1 - 9.5e-09 35.1 1.6 9.5e-09 35.1 1.6 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sin3a_C PF16879.5 EIM84851.1 - 0.059 13.1 1.5 1.9 8.1 0.2 2.4 2 0 0 2 2 2 0 C-terminal domain of Sin3a protein Pec_lyase_C PF00544.19 EIM84852.1 - 1.4e-09 37.8 12.5 1.5e-08 34.5 12.5 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EIM84852.1 - 2.1e-08 34.2 13.3 7.9e-08 32.3 12.8 2.0 1 1 1 2 2 2 2 Right handed beta helix region DUF4957 PF16318.5 EIM84852.1 - 0.012 15.5 1.3 0.053 13.5 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4957) DUF5123 PF17161.4 EIM84852.1 - 0.014 16.5 1.2 0.02 16.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) DUF5127 PF17168.4 EIM84853.1 - 3.8e-74 249.3 4.2 3.8e-74 249.3 4.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM84853.1 - 8.5e-55 185.1 0.5 1.8e-54 184.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM84853.1 - 8.2e-30 104.4 0.9 8.2e-30 104.4 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM84853.1 - 0.0023 17.5 0.1 0.005 16.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Ribonuc_L-PSP PF01042.21 EIM84853.1 - 0.035 14.1 0.4 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 Endoribonuclease L-PSP Mito_carr PF00153.27 EIM84854.1 - 4.9e-21 74.5 10.0 2.7e-09 36.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EIM84855.1 - 6.8e-42 140.7 15.9 4.9e-08 33.5 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM84855.1 - 0.00051 20.3 0.9 1 9.7 0.2 4.2 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM84855.1 - 0.00089 18.0 0.7 3.4 6.2 0.0 3.9 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM84855.1 - 0.15 11.4 0.0 0.49 9.7 0.0 1.8 1 1 1 2 2 2 0 WD40-like domain Hydrolase_3 PF08282.12 EIM84856.1 - 1.3e-40 139.8 0.0 7.9e-22 78.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EIM84856.1 - 2.9e-08 33.5 0.1 0.0065 16.0 0.0 3.0 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EIM84856.1 - 3.3e-05 24.3 0.9 0.051 13.9 0.1 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EIM84856.1 - 0.0007 20.0 0.0 0.14 12.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EIM84856.1 - 0.014 15.5 1.0 4.5 7.3 0.0 3.5 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 EIM84856.1 - 0.12 11.5 0.0 0.88 8.7 0.0 1.9 2 0 0 2 2 2 0 Trehalose-phosphatase DUF2470 PF10615.9 EIM84858.1 - 1.9e-18 66.8 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 EIM84858.1 - 2.4e-07 31.0 1.6 2.4e-07 31.0 1.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) GIDA PF01134.22 EIM84860.1 - 9.9e-140 466.0 0.0 4e-70 236.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A GIDA_assoc PF13932.6 EIM84860.1 - 8e-66 222.2 0.0 1.2e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EIM84860.1 - 1.3e-07 31.4 0.4 2.2e-07 30.6 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM84860.1 - 4.6e-06 26.1 1.9 1.6e-05 24.3 1.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM84860.1 - 0.0002 20.6 1.7 0.00044 19.4 1.7 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EIM84860.1 - 0.001 17.9 1.7 0.056 12.1 0.5 2.6 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 EIM84860.1 - 0.0032 17.1 0.3 0.41 10.2 0.5 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM84860.1 - 0.013 16.0 0.2 0.041 14.5 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM84860.1 - 0.022 14.1 0.2 0.022 14.1 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EIM84860.1 - 0.059 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM84860.1 - 0.12 12.7 1.5 0.38 11.0 1.5 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SPX PF03105.19 EIM84860.1 - 0.95 9.3 3.5 1.4 8.7 3.5 1.2 1 0 0 1 1 1 0 SPX domain NUDE_C PF04880.13 EIM84860.1 - 8.5 6.8 13.6 16 5.9 13.6 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ATG22 PF11700.8 EIM84861.1 - 1e-150 502.5 2.7 1.2e-150 502.3 2.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EIM84861.1 - 3.1e-11 42.8 61.0 4.7e-06 25.8 16.6 3.9 3 1 1 4 4 4 3 Major Facilitator Superfamily Pec_lyase_C PF00544.19 EIM84862.1 - 1.8e-12 47.3 11.0 1.8e-11 44.1 11.0 2.0 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EIM84862.1 - 7.1e-08 32.4 16.8 2.3e-07 30.8 15.6 2.1 1 1 1 2 2 2 2 Right handed beta helix region DUF5123 PF17161.4 EIM84862.1 - 0.045 14.8 1.6 0.069 14.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) DUF4957 PF16318.5 EIM84862.1 - 0.11 12.5 5.3 0.86 9.5 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4957) AFT PF08731.11 EIM84864.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription factor AFT PIP5K PF01504.18 EIM84865.1 - 4.4e-47 160.6 3.4 2.7e-39 135.1 0.1 2.5 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase adh_short PF00106.25 EIM84866.1 - 6.1e-26 91.1 0.0 8.7e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84866.1 - 1.5e-20 73.8 0.0 1.9e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 EIM84866.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EIM84866.1 - 0.049 12.7 0.9 0.25 10.4 0.8 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 EIM84867.1 - 1.2e-64 218.5 0.0 2.1e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM84867.1 - 2.4e-35 122.2 0.0 4.4e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM84867.1 - 9e-06 25.0 0.1 1.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EIM84867.1 - 0.00044 19.6 0.1 0.0017 17.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EIM84867.1 - 0.0029 16.7 0.4 0.026 13.6 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM84867.1 - 0.058 12.6 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM84867.1 - 0.15 10.8 1.0 0.23 10.1 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein SKG6 PF08693.10 EIM84868.1 - 0.0088 15.4 2.6 0.017 14.5 2.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Peptidase_M56 PF05569.11 EIM84868.1 - 0.076 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DAG1 PF05454.11 EIM84869.1 - 0.00012 21.5 0.2 0.00018 21.0 0.2 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) CE2_N PF17996.1 EIM84869.1 - 0.00082 19.3 0.9 0.018 15.0 0.0 2.8 2 1 0 2 2 2 1 Carbohydrate esterase 2 N-terminal CBM_6 PF03422.15 EIM84869.1 - 0.12 12.7 1.8 3.5 8.0 0.0 2.8 2 2 0 2 2 2 0 Carbohydrate binding module (family 6) EphA2_TM PF14575.6 EIM84869.1 - 0.14 13.0 0.0 0.27 12.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fn3_assoc PF13287.6 EIM84869.1 - 0.23 11.6 2.5 0.52 10.5 0.1 2.6 2 0 0 2 2 2 0 Fn3 associated Pro_isomerase PF00160.21 EIM84870.1 - 2.2e-49 167.7 0.1 2.5e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DIM1 PF02966.16 EIM84871.1 - 4.2e-68 227.2 0.1 4.7e-68 227.1 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EIM84871.1 - 2.2e-05 24.4 0.1 2.8e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EIM84871.1 - 0.0074 16.6 0.5 0.011 16.0 0.5 1.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 EIM84871.1 - 0.011 15.7 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 zf-CSL PF05207.13 EIM84872.1 - 3.8e-21 74.6 2.0 3.8e-21 74.6 2.0 1.9 2 1 0 2 2 2 1 CSL zinc finger Sporozoite_P67 PF05642.11 EIM84872.1 - 0.0084 14.3 4.1 0.0094 14.1 4.1 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CobT PF06213.12 EIM84872.1 - 0.03 13.7 8.0 0.033 13.6 8.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 EIM84872.1 - 0.047 13.4 3.8 0.068 12.8 3.8 1.3 1 0 0 1 1 1 0 FAM176 family zf-RING_7 PF02591.15 EIM84872.1 - 0.067 13.4 0.5 0.14 12.3 0.5 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain Nop16 PF09420.10 EIM84872.1 - 0.14 12.2 0.8 0.19 11.7 0.8 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF5423 PF17461.2 EIM84872.1 - 0.4 9.5 2.7 0.52 9.1 2.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) SDA1 PF05285.12 EIM84872.1 - 0.48 9.8 10.4 0.54 9.6 10.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIM84872.1 - 0.66 8.1 11.8 0.79 7.9 11.8 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EIM84872.1 - 0.85 8.0 12.0 1.1 7.6 8.8 1.9 2 0 0 2 2 2 0 Mpp10 protein ATHILA PF03078.15 EIM84872.1 - 1.1 8.0 2.6 1.3 7.8 2.6 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family GAGA PF09237.11 EIM84872.1 - 1.1 9.1 3.0 0.91 9.4 1.3 1.8 2 1 0 2 2 2 0 GAGA factor eIF-3c_N PF05470.12 EIM84872.1 - 1.7 6.9 9.0 2.1 6.6 9.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 EIM84872.1 - 2.2 6.5 9.0 2.6 6.2 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EIM84872.1 - 3 6.3 8.9 3.3 6.1 8.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EIM84872.1 - 4.2 6.6 11.0 4.9 6.4 11.0 1.0 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 EIM84872.1 - 4.9 5.6 12.8 6.2 5.3 12.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) F-box-like PF12937.7 EIM84875.1 - 9.3e-06 25.4 0.6 1.8e-05 24.5 0.6 1.5 1 0 0 1 1 1 1 F-box-like Abhydrolase_1 PF00561.20 EIM84876.1 - 3.4e-15 56.4 0.0 6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM84876.1 - 7.4e-14 52.9 0.1 9.4e-14 52.5 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM84876.1 - 1.7e-10 40.6 0.0 1.8e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EIM84876.1 - 0.0023 16.6 0.0 0.015 14.0 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EIM84876.1 - 0.091 12.2 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase PF07224.11 EIM84876.1 - 0.19 10.7 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 EIM84876.1 - 0.22 10.4 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EIM84877.1 - 6e-17 62.1 0.1 8.8e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM84877.1 - 3.5e-12 47.4 0.0 4.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM84877.1 - 9.1e-05 21.8 0.0 0.00022 20.6 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 EIM84877.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Ubiq_cyt_C_chap PF03981.12 EIM84878.1 - 5.2e-28 97.9 0.4 3.5e-13 49.8 0.0 3.0 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone CBFD_NFYB_HMF PF00808.23 EIM84879.1 - 1e-08 35.3 0.1 1.6e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EIM84879.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PPP4R2 PF09184.11 EIM84879.1 - 0.21 11.1 4.0 0.27 10.8 4.0 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EIM84879.1 - 2.5 7.3 14.1 3.9 6.7 14.1 1.3 1 0 0 1 1 1 0 NOA36 protein Prothymosin PF03247.14 EIM84879.1 - 3 8.4 25.3 8.8 6.8 25.3 1.8 1 0 0 1 1 1 0 Prothymosin/parathymosin family zf-MYND PF01753.18 EIM84880.1 - 4.1e-09 36.4 9.3 4.1e-09 36.4 9.3 2.6 2 1 1 3 3 3 1 MYND finger C1_2 PF03107.16 EIM84880.1 - 3.6 8.0 9.2 0.6 10.5 4.9 2.1 2 0 0 2 2 2 0 C1 domain Helicase_C PF00271.31 EIM84881.1 - 2.8e-07 30.8 0.1 4.9e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MRG PF05712.13 EIM84882.1 - 3.8e-52 176.5 0.0 6.7e-52 175.7 0.0 1.3 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 EIM84882.1 - 3.5e-09 36.4 0.0 6.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 EIM84882.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 PWWP domain DUF3123 PF11321.8 EIM84882.1 - 0.086 13.5 0.1 0.15 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Chromo PF00385.24 EIM84882.1 - 0.093 12.7 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.7 EIM84884.1 - 3.6e-05 23.6 0.4 7.8e-05 22.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like Gpr1_Fun34_YaaH PF01184.19 EIM84885.1 - 4.3e-29 101.6 18.7 5.3e-29 101.3 18.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family AA_permease_2 PF13520.6 EIM84886.1 - 6.2e-75 252.6 52.5 7.4e-75 252.4 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM84886.1 - 5.4e-16 58.2 45.9 7.1e-16 57.9 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.12 EIM84886.1 - 1.4 8.5 7.4 0.38 10.4 3.3 2.2 1 1 0 1 1 1 0 Mediator of CRAC channel activity Amino_oxidase PF01593.24 EIM84887.1 - 6.6e-41 141.1 0.0 8.6e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIM84887.1 - 0.0035 17.5 0.0 0.017 15.3 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TetR_C_14 PF17754.1 EIM84888.1 - 0.22 11.5 3.9 8.1 6.4 0.1 2.2 2 0 0 2 2 2 0 MftR C-terminal domain F-box-like PF12937.7 EIM84889.1 - 0.044 13.7 0.1 0.099 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like DUF4349 PF14257.6 EIM84890.1 - 0.023 14.1 0.1 0.093 12.2 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) F-box-like PF12937.7 EIM84892.1 - 0.00022 21.0 0.2 0.00076 19.3 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM84892.1 - 0.041 13.8 1.8 0.27 11.1 0.1 2.6 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 EIM84892.1 - 0.064 13.7 3.3 6.3 7.4 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) JmjN PF02375.17 EIM84892.1 - 0.13 12.3 3.3 12 6.0 0.0 3.4 3 0 0 3 3 3 0 jmjN domain Pkinase PF00069.25 EIM84893.1 - 1e-11 44.7 0.0 1.8e-09 37.4 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM84893.1 - 0.00067 19.0 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3494 PF11999.8 EIM84895.1 - 1.4e-54 184.9 12.9 1.7e-54 184.6 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) zf-C2H2 PF00096.26 EIM84896.1 - 1.4e-08 34.8 13.2 3.6e-06 27.1 0.3 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM84896.1 - 1.2e-07 31.8 6.4 6.5e-07 29.5 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 EIM84896.1 - 1.6e-06 28.7 6.3 0.0083 16.7 2.9 2.8 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EIM84896.1 - 0.00048 20.7 7.2 0.0098 16.7 0.2 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIM84896.1 - 0.023 14.7 0.5 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EIM84896.1 - 0.061 13.7 0.1 5.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EIM84896.1 - 0.47 10.8 1.6 19 5.7 0.0 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 EIM84896.1 - 0.64 10.4 5.0 1.3 9.4 0.2 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zap1_zf2 PF18217.1 EIM84896.1 - 1.5 8.9 13.2 0.14 12.2 5.9 2.7 3 0 0 3 3 3 0 Zap1 zinc finger 2 TAFII28 PF04719.14 EIM84897.1 - 2e-34 117.5 0.1 2.9e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 EIM84897.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ORC2 PF04084.14 EIM84898.1 - 3e-91 305.8 0.0 3.8e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ICMT PF04140.14 EIM84900.1 - 4.2e-13 49.5 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM84900.1 - 3e-12 46.9 0.2 2.3e-11 44.0 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM84900.1 - 4.6e-05 22.4 0.1 0.00011 21.1 0.1 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 EIM84900.1 - 0.0017 18.3 0.0 0.0069 16.4 0.0 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EIM84900.1 - 0.031 13.8 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PEMT PF04191.13 EIM84901.1 - 3.4e-13 49.9 0.4 2.1e-12 47.4 0.2 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EIM84901.1 - 1.2e-12 48.1 0.0 3.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 EIM84901.1 - 0.0034 16.2 0.0 0.0099 14.7 0.0 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIM84901.1 - 0.007 15.9 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EIM84902.1 - 7.4e-13 48.7 0.0 6.8e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM84902.1 - 1.5e-12 47.8 0.1 9.5e-12 45.3 0.1 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM84902.1 - 0.0007 18.5 0.0 0.0016 17.3 0.0 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 EIM84903.1 - 4.5e-13 49.4 0.1 3.2e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM84903.1 - 1.7e-12 47.6 0.4 6.7e-12 45.7 0.2 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM84903.1 - 0.0005 19.0 0.0 0.0013 17.6 0.0 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIM84903.1 - 0.057 12.9 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PGI PF00342.19 EIM84904.1 - 0.18 10.3 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase adh_short PF00106.25 EIM84905.1 - 4.3e-40 137.3 0.0 5.6e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84905.1 - 8.8e-26 90.9 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EIM84905.1 - 1.4e-08 34.5 0.0 1.2e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EIM84905.1 - 0.00021 20.8 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM84905.1 - 0.00031 20.7 0.0 0.00066 19.6 0.0 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EIM84905.1 - 0.0075 16.5 0.1 0.011 16.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EIM84905.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SseC PF04888.12 EIM84906.1 - 0.021 14.5 4.2 0.023 14.3 4.2 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SLD5_C PF16922.5 EIM84907.1 - 2.2e-07 31.0 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EIM84907.1 - 2.3e-06 28.0 0.1 3.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein Vg_Tdu PF07545.14 EIM84907.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Vestigial/Tondu family NAD_binding_4 PF07993.12 EIM84908.1 - 2.8e-31 108.6 0.0 7.5e-31 107.2 0.0 1.8 2 1 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EIM84908.1 - 5e-27 94.6 0.1 1.7e-26 92.8 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM84908.1 - 2.3e-06 27.2 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM84908.1 - 0.0025 18.1 0.0 0.0083 16.5 0.0 2.0 1 1 0 1 1 1 1 Phosphopantetheine attachment site Lipid_DES PF08557.10 EIM84908.1 - 0.14 11.6 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) 2-Hacid_dh_C PF02826.19 EIM84909.1 - 2.9e-44 150.5 0.0 4.2e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM84909.1 - 9.2e-20 70.7 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EIM84909.1 - 4.8e-05 22.7 0.0 0.046 13.0 0.0 2.2 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EIM84909.1 - 5.4e-05 23.4 0.0 0.00013 22.2 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peripla_BP_4 PF13407.6 EIM84909.1 - 0.024 14.2 0.0 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain Shikimate_DH PF01488.20 EIM84909.1 - 0.029 14.4 0.0 0.66 10.0 0.0 2.6 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase His_Phos_1 PF00300.22 EIM84911.1 - 4.3e-22 78.8 0.0 1.5e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Glyco_hydro_75 PF07335.11 EIM84913.1 - 9.8e-16 58.5 0.1 1.6e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Xan_ur_permease PF00860.20 EIM84914.1 - 7.1e-29 100.7 29.3 5.1e-28 97.9 29.3 2.2 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EIM84914.1 - 0.0012 19.2 4.7 0.0012 19.2 4.7 2.7 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 EIM84914.1 - 0.14 11.8 0.7 0.38 10.4 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4956) NUFIP2 PF15293.6 EIM84915.1 - 0.0074 15.2 0.4 0.011 14.7 0.4 1.2 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Med8 PF10232.9 EIM84915.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF2848 PF11010.8 EIM84916.1 - 0.037 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) TIC20 PF16166.5 EIM84916.1 - 5.8 6.7 11.1 3.7 7.3 6.4 2.5 2 1 1 3 3 3 0 Chloroplast import apparatus Tic20-like p450 PF00067.22 EIM84917.1 - 1.6e-61 208.5 0.0 2.1e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRP72 PF08492.12 EIM84917.1 - 0.19 12.2 0.3 0.39 11.2 0.3 1.4 1 0 0 1 1 1 0 SRP72 RNA-binding domain MFS_1 PF07690.16 EIM84918.1 - 1.4e-23 83.4 90.4 2.2e-17 63.0 54.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 EIM84919.1 - 8.6e-37 127.5 0.0 1e-36 127.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM84919.1 - 5.7e-05 22.4 0.0 9.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM84919.1 - 0.00026 20.3 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM84919.1 - 0.00089 18.4 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM84919.1 - 0.0019 18.4 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 EIM84919.1 - 0.038 13.3 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 EIM84919.1 - 0.041 14.4 0.2 0.61 10.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM84919.1 - 0.059 12.6 0.1 0.089 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EIM84919.1 - 0.06 12.6 0.0 1.2 8.4 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EIM84919.1 - 0.08 12.3 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase Ank PF00023.30 EIM84919.1 - 0.11 13.0 0.0 33 5.1 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat NAD_binding_9 PF13454.6 EIM84919.1 - 0.11 12.4 0.2 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EIM84919.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cys_Met_Meta_PP PF01053.20 EIM84920.1 - 1.6e-140 468.0 0.0 1.8e-140 467.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EIM84920.1 - 3.1e-11 43.2 0.5 5.9e-11 42.3 0.5 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EIM84920.1 - 9.7e-11 41.4 0.1 1.7e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EIM84920.1 - 2.8e-10 39.7 0.9 9.3e-10 38.0 0.9 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EIM84920.1 - 0.00015 20.4 0.1 0.00021 20.0 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EIM84920.1 - 0.00075 18.9 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EIM84920.1 - 0.0018 17.2 0.0 0.0026 16.7 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SepSecS PF05889.13 EIM84920.1 - 0.053 12.2 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Epimerase PF01370.21 EIM84921.1 - 4.7e-25 88.4 0.1 9.5e-25 87.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM84921.1 - 4.8e-18 65.1 0.0 7.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM84921.1 - 1.3e-15 57.3 0.1 6.1e-13 48.5 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EIM84921.1 - 2.1e-14 53.9 0.6 3.5e-14 53.1 0.6 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIM84921.1 - 1.4e-12 47.7 0.0 3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIM84921.1 - 2.5e-08 33.4 0.2 5.5e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EIM84921.1 - 3.1e-08 33.5 0.3 5e-08 32.8 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EIM84921.1 - 5.8e-05 22.6 1.5 0.00087 18.8 0.6 2.6 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EIM84921.1 - 0.00032 19.9 0.0 0.061 12.4 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.10 EIM84921.1 - 0.048 13.6 1.8 0.68 9.8 1.8 2.1 1 1 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 EIM84921.1 - 0.089 12.7 0.3 2.8 7.8 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.13 EIM84921.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family FA_hydroxylase PF04116.13 EIM84922.1 - 2.3e-23 83.0 21.8 2.3e-23 83.0 21.8 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily DUF89 PF01937.19 EIM84922.1 - 0.13 11.1 0.5 0.29 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF89 Lactamase_B_2 PF12706.7 EIM84923.1 - 5.9e-17 61.8 0.9 1.4e-16 60.6 0.6 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EIM84923.1 - 2.1e-12 47.2 8.7 3e-12 46.7 2.4 2.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM84923.1 - 0.015 15.3 8.7 0.0085 16.1 5.8 2.2 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily Abhydrolase_1 PF00561.20 EIM84924.1 - 6.5e-16 58.7 0.3 1.2e-15 57.9 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM84924.1 - 4.9e-14 53.5 0.1 7.2e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM84924.1 - 9e-07 28.4 0.0 1.8e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EIM84924.1 - 0.074 11.7 0.1 0.25 10.0 0.1 1.8 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) p450 PF00067.22 EIM84926.1 - 5.7e-66 223.2 0.0 1.6e-65 221.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM84927.1 - 2.2e-68 231.1 0.0 1.6e-67 228.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF92 PF01940.16 EIM84929.1 - 1.1e-68 231.3 6.4 1.2e-68 231.0 6.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Asp PF00026.23 EIM84930.1 - 1.3e-39 136.4 0.7 1.1e-20 74.3 3.7 3.2 2 2 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM84930.1 - 0.0036 17.5 8.9 0.21 11.8 0.3 3.5 4 1 1 5 5 5 2 Xylanase inhibitor N-terminal zf-C2H2_aberr PF17017.5 EIM84934.1 - 0.067 13.3 7.7 1.9 8.6 0.6 2.7 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2 PF00096.26 EIM84934.1 - 0.28 11.7 12.9 0.056 13.9 1.3 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM84934.1 - 6.8 7.8 15.3 2.4 9.2 0.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger EamA PF00892.20 EIM84935.1 - 3.8e-26 91.9 30.9 5.7e-16 58.9 9.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 EIM84935.1 - 0.0027 16.1 4.1 0.0027 16.1 4.1 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2070) DUF3433 PF11915.8 EIM84936.1 - 2e-17 63.4 5.8 5.4e-17 62.0 5.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) p450 PF00067.22 EIM84937.1 - 1.4e-66 225.2 0.0 4.1e-66 223.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EIM84938.1 - 2.1e-31 108.9 0.1 3.1e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84938.1 - 4.3e-31 108.3 0.2 2.1e-27 96.2 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM84938.1 - 6.4e-08 32.7 0.1 1.2e-07 31.8 0.1 1.4 1 1 0 1 1 1 1 KR domain SpoVAD PF07451.11 EIM84938.1 - 0.042 12.6 0.1 0.054 12.2 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) 3HCDH_N PF02737.18 EIM84938.1 - 0.067 13.1 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Yop-YscD_ppl PF16693.5 EIM84938.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain HEM4 PF02602.15 EIM84938.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Questin_oxidase PF14027.6 EIM84939.1 - 1.6e-72 244.9 0.0 1.9e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like UPF0172 PF03665.13 EIM84940.1 - 4e-51 173.8 0.0 4.9e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EIM84940.1 - 0.00023 21.1 0.0 0.00051 20.0 0.0 1.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Folliculin PF11704.8 EIM84941.1 - 0.11 12.4 0.2 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport F-box-like PF12937.7 EIM84942.1 - 1.5e-05 24.8 0.4 1.5e-05 24.8 0.4 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM84942.1 - 0.1 12.5 1.5 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 F-box domain TPR_14 PF13428.6 EIM84943.1 - 7.3e-13 48.2 20.3 0.0026 18.4 0.0 7.9 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM84943.1 - 6.2e-08 32.2 16.8 9.5e-05 22.2 0.0 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM84943.1 - 2.4e-07 31.3 16.6 0.00069 20.2 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM84943.1 - 3e-07 30.1 3.6 0.014 15.6 0.0 5.9 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM84943.1 - 3.6e-06 27.4 5.7 0.57 10.7 0.4 4.9 4 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM84943.1 - 6.1e-05 23.2 0.3 1.8 8.8 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EIM84943.1 - 0.00012 21.7 9.1 0.0007 19.3 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIM84943.1 - 0.0011 18.2 0.3 1.6 7.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM84943.1 - 0.015 15.9 8.2 68 4.4 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EIM84943.1 - 0.022 15.1 0.3 81 3.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EIM84943.1 - 0.049 13.8 10.8 1.4 9.1 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EIM84943.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 EIM84943.1 - 0.059 13.4 2.2 10 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Acyltransferase PF01553.21 EIM84944.1 - 7e-23 80.7 0.1 1.5e-22 79.6 0.0 1.5 1 1 1 2 2 2 1 Acyltransferase adh_short PF00106.25 EIM84945.1 - 3.3e-31 108.3 0.0 4.4e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM84945.1 - 5.1e-28 98.2 0.0 7.5e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM84945.1 - 0.0001 22.3 0.6 0.00015 21.7 0.2 1.4 2 0 0 2 2 2 1 KR domain Na_Ca_ex PF01699.24 EIM84946.1 - 6.3e-14 52.2 25.9 7.3e-08 32.5 1.7 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein BSP_II PF05432.11 EIM84948.1 - 0.00038 20.2 25.1 0.00048 19.9 25.1 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Pilosulin PF17499.2 EIM84948.1 - 0.47 10.7 2.4 1.1 9.4 2.4 1.6 1 0 0 1 1 1 0 Ant venom peptides PhyH PF05721.13 EIM84949.1 - 6.8e-10 39.6 0.0 1e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2236 PF09995.9 EIM84950.1 - 1.6e-06 28.5 0.2 2.6e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) p450 PF00067.22 EIM84951.1 - 2.7e-65 220.9 0.0 4.1e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PARP PF00644.20 EIM84952.1 - 4e-16 59.2 0.2 4.4e-12 46.0 0.2 3.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-C2H2_jaz PF12171.8 EIM84952.1 - 0.33 11.3 0.2 0.33 11.3 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Pyr_redox_2 PF07992.14 EIM84953.1 - 1.1e-37 129.8 0.1 3.4e-36 125.0 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM84953.1 - 5.9e-14 52.4 0.1 1e-10 42.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM84953.1 - 2e-10 40.4 0.1 4.8e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM84953.1 - 4.2e-08 32.7 0.1 2.3e-05 23.7 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EIM84953.1 - 2.5e-05 24.0 0.3 0.39 10.2 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM84953.1 - 5.6e-05 22.0 0.0 0.51 9.0 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 EIM84953.1 - 0.00032 20.7 0.4 0.094 12.7 0.0 3.8 4 1 1 5 5 5 1 FAD-NAD(P)-binding TrkA_N PF02254.18 EIM84953.1 - 0.0015 18.7 0.0 0.32 11.3 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_7 PF13241.6 EIM84953.1 - 0.0031 17.9 0.0 0.87 10.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding DHFR_1 PF00186.19 EIM84953.1 - 0.005 16.6 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 1 Dihydrofolate reductase Lycopene_cycl PF05834.12 EIM84953.1 - 0.0083 15.2 0.0 0.27 10.2 0.0 2.3 1 1 1 2 2 2 1 Lycopene cyclase protein DUF1188 PF06690.11 EIM84953.1 - 0.026 14.1 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Glyco_tran_28_C PF04101.16 EIM84953.1 - 0.054 13.5 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Sacchrp_dh_NADP PF03435.18 EIM84953.1 - 1 9.6 2.7 29 4.9 0.0 3.1 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain AMP-binding PF00501.28 EIM84954.1 - 2.2e-33 115.5 0.1 1.4e-32 112.9 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EIM84954.1 - 4e-27 95.0 0.0 1.3e-26 93.3 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EIM84954.1 - 0.00065 19.2 0.0 0.0018 17.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM84954.1 - 0.013 15.9 0.1 0.091 13.1 0.0 2.5 2 1 0 2 2 2 0 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EIM84954.1 - 0.025 13.6 0.0 0.89 8.5 0.0 2.4 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM84955.1 - 7e-30 104.0 0.0 2.3e-29 102.4 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EIM84955.1 - 6.6e-29 100.7 0.0 1.3e-28 99.8 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM84955.1 - 4.9e-05 22.9 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM84955.1 - 0.062 13.7 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Pyr_redox_2 PF07992.14 EIM84956.1 - 1.9e-34 119.3 0.0 2.5e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM84956.1 - 3e-13 50.1 0.1 1.9e-10 41.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM84956.1 - 0.00012 21.5 0.0 0.0015 17.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM84956.1 - 0.0018 18.5 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM84956.1 - 0.0024 17.5 0.0 1.1 8.8 0.0 3.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIM84956.1 - 0.0057 15.6 0.1 0.39 9.5 0.0 2.4 2 0 0 2 2 2 1 Tryptophan halogenase K_oxygenase PF13434.6 EIM84956.1 - 0.0067 15.6 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EIM84956.1 - 0.021 13.5 0.0 4.6 5.8 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein Trp_ring PF18669.1 EIM84956.1 - 0.027 14.6 0.3 0.058 13.6 0.3 1.5 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain Lycopene_cycl PF05834.12 EIM84956.1 - 0.034 13.2 0.0 0.91 8.5 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EIM84956.1 - 0.097 11.9 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 EIM84956.1 - 0.11 12.8 0.1 5.8 7.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 EIM84956.1 - 0.13 12.3 0.1 9.8 6.1 0.0 3.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding ThiF PF00899.21 EIM84956.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 ThiF family PI-PLC-X PF00388.19 EIM84957.1 - 1e-42 145.1 0.0 1.8e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EIM84957.1 - 3.3e-31 108.0 0.0 5.4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SIT PF15330.6 EIM84958.1 - 0.093 13.2 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TRP PF06011.12 EIM84958.1 - 0.27 9.9 0.3 0.35 9.5 0.3 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel VIR_N PF15912.5 EIM84958.1 - 7.7 6.0 8.2 0.9 9.1 4.0 1.5 1 1 1 2 2 2 0 Virilizer, N-terminal CPSase_L_D2 PF02786.17 EIM84959.1 - 9.3e-114 378.2 0.2 1.9e-81 272.6 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EIM84959.1 - 4.3e-49 165.6 0.0 1.2e-48 164.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EIM84959.1 - 5.7e-47 159.9 0.0 7e-46 156.4 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EIM84959.1 - 7.5e-45 152.6 0.0 1.7e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EIM84959.1 - 5.9e-42 142.9 0.0 1.4e-41 141.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EIM84959.1 - 1.2e-30 106.6 0.0 5.8e-30 104.4 0.0 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EIM84959.1 - 4.6e-19 68.4 0.0 1.5e-18 66.7 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EIM84959.1 - 3.5e-17 62.6 0.3 2.9e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EIM84959.1 - 1.4e-14 54.0 0.2 2.5e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EIM84959.1 - 8.2e-10 38.5 0.0 0.00012 21.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EIM84959.1 - 2.8e-05 24.2 0.3 0.015 15.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EIM84959.1 - 6.3e-05 22.8 0.3 0.0041 16.9 0.3 2.8 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.11 EIM84959.1 - 0.02 14.5 0.0 1.3 8.5 0.0 2.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.24 EIM84959.1 - 0.046 13.5 0.0 3.9 7.2 0.0 3.8 5 0 0 5 5 5 0 DJ-1/PfpI family Glyco_hydro_3 PF00933.21 EIM84960.1 - 1.3e-47 162.8 0.0 1.7e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EIM84960.1 - 7.9e-46 156.6 0.0 3.3e-45 154.6 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EIM84960.1 - 1.9e-15 56.7 0.1 3.7e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EIM84960.1 - 2.1e-08 34.1 0.3 7.4e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 PA14 domain Glyco_hydro_53 PF07745.13 EIM84961.1 - 9.3e-81 271.4 0.1 1.1e-80 271.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Tubulin PF00091.25 EIM84962.1 - 1.2e-66 224.7 0.0 2e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIM84962.1 - 5.9e-43 146.0 0.1 9.6e-43 145.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EIM84962.1 - 3.5e-05 24.1 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EIM84962.1 - 0.0087 15.3 0.0 0.029 13.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EIM84962.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Glyco_trans_2_3 PF13632.6 EIM84964.1 - 8.7e-57 192.2 0.2 8.7e-57 192.2 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIM84964.1 - 2.1e-05 24.5 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIM84964.1 - 0.0018 18.1 0.0 0.0066 16.3 0.0 1.9 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIM84964.1 - 0.17 11.3 0.0 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 EIM84966.1 - 9.1e-22 77.4 0.2 1.6e-21 76.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Prefoldin PF02996.17 EIM84967.1 - 1.8e-27 95.6 2.3 2.2e-27 95.4 2.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EIM84967.1 - 0.00016 21.7 0.3 0.00029 20.8 0.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 EIM84967.1 - 0.00027 21.1 0.9 0.11 12.8 0.1 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 EIM84967.1 - 0.003 17.7 2.6 0.34 11.1 0.3 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family Med30 PF11315.8 EIM84967.1 - 0.0049 17.1 2.9 0.029 14.6 1.4 2.0 1 1 1 2 2 2 1 Mediator complex subunit 30 CLZ PF16526.5 EIM84967.1 - 0.0068 16.7 3.5 0.17 12.3 0.3 2.5 2 1 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EIM84967.1 - 0.021 14.9 1.9 3 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EIM84967.1 - 0.031 14.3 2.1 1.9 8.5 0.1 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 EIM84967.1 - 0.037 14.3 0.3 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.20 EIM84967.1 - 0.039 13.9 5.2 0.1 12.6 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit CEP63 PF17045.5 EIM84967.1 - 0.044 13.7 3.5 3.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa OmpH PF03938.14 EIM84967.1 - 0.062 13.6 4.9 0.1 13.0 0.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) XkdW PF09636.10 EIM84967.1 - 0.074 13.1 0.3 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 XkdW protein DUF4140 PF13600.6 EIM84967.1 - 0.082 13.4 0.1 9.5 6.7 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2552 PF10827.8 EIM84967.1 - 0.12 12.6 0.1 6.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) SlyX PF04102.12 EIM84967.1 - 0.14 12.8 3.2 3.5 8.3 0.2 2.4 2 0 0 2 2 2 0 SlyX NPV_P10 PF05531.12 EIM84967.1 - 0.42 11.1 4.0 1.4 9.4 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 EIM84967.1 - 0.58 9.5 4.7 0.94 8.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 EIM84967.1 - 0.88 9.6 8.0 3.7 7.6 0.4 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 EIM84967.1 - 0.88 9.5 7.2 0.36 10.7 0.3 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MAGE PF01454.19 EIM84968.1 - 1.4e-52 178.5 0.1 1.4e-52 178.5 0.1 1.5 2 0 0 2 2 2 1 MAGE family PBP1_TM PF14812.6 EIM84968.1 - 0.099 13.0 19.8 0.47 10.8 2.1 3.9 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4809 PF16067.5 EIM84968.1 - 0.16 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) DDDD PF10161.9 EIM84968.1 - 0.18 11.6 0.6 0.54 10.1 0.6 1.8 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Cnn_1N PF07989.11 EIM84968.1 - 0.21 11.8 1.6 0.47 10.6 0.8 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF2254 PF10011.9 EIM84969.1 - 0.014 14.2 0.1 0.029 13.2 0.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF1418 PF07214.12 EIM84969.1 - 0.05 13.5 0.4 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) PIN_4 PF13638.6 EIM84971.1 - 5.7e-07 29.9 0.0 8.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 PIN domain HEM4 PF02602.15 EIM84971.1 - 0.042 13.2 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DUF2347 PF09804.9 EIM84972.1 - 7.4e-50 170.1 0.0 1.2e-36 126.8 0.0 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 EIM84972.1 - 1.1e-06 27.6 0.0 0.011 14.5 0.0 2.8 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EIM84972.1 - 0.00041 20.3 0.0 0.0063 16.5 0.0 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis DUF4484 PF14831.6 EIM84972.1 - 0.011 15.8 0.0 0.058 13.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Lactamase_B PF00753.27 EIM84973.1 - 1.6e-07 31.5 5.2 2.7e-07 30.8 5.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIM84973.1 - 0.0089 15.6 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LuxQ-periplasm PF09308.10 EIM84973.1 - 0.3 10.6 0.0 0.45 10.0 0.0 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic SAC3_GANP PF03399.16 EIM84974.1 - 5.4e-59 200.0 2.2 8.5e-59 199.3 2.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family WSC PF01822.19 EIM84975.1 - 9.5e-68 224.4 49.8 2.9e-18 65.8 12.3 4.2 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 EIM84975.1 - 7.9e-27 94.0 0.0 1.4e-24 86.7 0.0 3.0 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM84975.1 - 6.5e-22 77.6 0.1 1.6e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 EIM84975.1 - 0.11 12.5 3.1 40 4.4 0.0 4.9 6 0 0 6 6 6 0 Kelch motif Gti1_Pac2 PF09729.9 EIM84976.1 - 2.6e-61 206.9 0.0 3.1e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Gti1/Pac2 family A_deaminase PF00962.22 EIM84977.1 - 7.8e-30 104.3 0.0 1.6e-28 100.0 0.0 2.1 2 0 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EIM84977.1 - 0.00038 20.7 0.0 0.00097 19.4 0.0 1.7 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal AMP-binding PF00501.28 EIM84978.1 - 3.3e-30 105.1 0.0 1.7e-29 102.7 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EIM84978.1 - 2.2e-27 95.8 0.0 4.4e-27 94.9 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EIM84978.1 - 1.8e-06 27.6 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM84978.1 - 0.00057 20.2 0.0 0.0022 18.3 0.0 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site DapB_N PF01113.20 EIM84978.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Transketolase_C PF02780.20 EIM84978.1 - 0.2 11.6 0.4 1.2 9.1 0.1 2.4 3 0 0 3 3 3 0 Transketolase, C-terminal domain DUF3246 PF11596.8 EIM84978.1 - 0.21 11.0 0.5 7.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) CybS PF05328.12 EIM84982.1 - 3.9e-46 156.0 0.1 4.2e-46 155.9 0.1 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit CrgA PF06781.12 EIM84982.1 - 0.041 13.9 0.0 0.08 13.0 0.0 1.4 1 1 0 1 1 1 0 Cell division protein CrgA ThiJ_like PF17124.5 EIM84983.1 - 1.6e-59 200.9 0.0 2e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 EIM84983.1 - 1.1e-10 41.5 0.0 3.9e-09 36.5 0.0 2.8 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EIM84983.1 - 0.0034 17.0 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain FHA PF00498.26 EIM84984.1 - 2.5e-09 37.4 0.0 4.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF1664 PF07889.12 EIM84984.1 - 0.00042 20.3 6.0 0.0013 18.8 1.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EIM84984.1 - 0.008 15.5 6.9 0.008 15.5 6.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Laminin_II PF06009.12 EIM84984.1 - 0.011 15.8 2.2 0.011 15.8 2.2 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 EIM84984.1 - 0.35 11.2 1.8 1.9 8.8 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.21 EIM84984.1 - 0.39 11.2 9.6 1.9 9.0 2.6 2.9 2 1 0 2 2 2 0 Spectrin repeat APG6_N PF17675.1 EIM84984.1 - 0.53 10.8 20.1 1.5 9.3 3.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region EzrA PF06160.12 EIM84984.1 - 0.99 7.5 9.5 0.31 9.1 4.5 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_13 PF13166.6 EIM84984.1 - 1.1 7.8 5.5 1.7 7.2 5.5 1.2 1 0 0 1 1 1 0 AAA domain DUF4201 PF13870.6 EIM84984.1 - 1.2 8.8 7.6 0.54 10.0 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 EIM84984.1 - 1.4 8.9 4.5 3.9 7.5 0.9 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EIM84984.1 - 1.9 9.0 4.3 3.6 8.1 1.3 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 EIM84984.1 - 2 7.4 15.6 14 4.7 15.6 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 EIM84984.1 - 3.6 8.0 8.1 12 6.2 2.9 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 EIM84984.1 - 3.7 7.1 6.6 5.2 6.6 2.5 2.5 2 0 0 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 EIM84984.1 - 4.6 7.4 8.3 1.5 9.0 3.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 EIM84984.1 - 4.8 7.3 22.6 2.1 8.4 10.3 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FUSC PF04632.12 EIM84984.1 - 8.4 4.8 13.5 12 4.2 13.1 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 EIM84984.1 - 8.6 5.1 16.1 0.61 8.9 6.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 EIM84984.1 - 8.6 5.6 16.7 5.6 6.2 13.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ATP_bind_1 PF03029.17 EIM84985.1 - 1.1e-73 248.0 0.0 1.8e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EIM84985.1 - 3.1e-05 23.6 0.0 0.001 18.6 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIM84985.1 - 0.00048 20.2 0.0 0.012 15.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EIM84985.1 - 0.00058 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIM84985.1 - 0.0016 18.6 0.0 0.0042 17.3 0.0 1.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EIM84985.1 - 0.0028 17.6 0.0 1.1 9.1 0.0 2.9 3 1 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 EIM84985.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MeaB PF03308.16 EIM84985.1 - 0.0056 15.7 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EIM84985.1 - 0.011 15.3 0.1 0.049 13.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 EIM84985.1 - 0.011 14.9 0.1 0.46 9.6 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 EIM84985.1 - 0.014 15.3 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 NTPase cobW PF02492.19 EIM84985.1 - 0.015 14.9 0.1 0.24 11.0 0.1 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EIM84985.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EIM84985.1 - 0.04 14.3 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EIM84985.1 - 0.058 13.0 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EIM84985.1 - 0.06 12.6 0.5 0.15 11.3 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EIM84985.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EIM84985.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EIM84985.1 - 0.15 12.7 0.1 1 9.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 EIM84986.1 - 1.7e-74 250.5 0.0 2e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM84986.1 - 5.5e-34 117.6 0.0 7.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM84986.1 - 3.7e-05 22.9 0.3 7.8e-05 21.8 0.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIM84986.1 - 0.004 16.5 0.1 0.23 10.7 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EIM84986.1 - 0.0074 16.2 0.1 0.049 13.6 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EIM84986.1 - 0.02 14.0 0.2 0.036 13.1 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 ABM PF03992.16 EIM84987.1 - 8.8e-08 32.2 0.1 1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SKG6 PF08693.10 EIM84988.1 - 0.00039 19.8 4.2 0.00039 19.8 4.2 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF202 PF02656.15 EIM84988.1 - 0.058 13.8 0.7 0.096 13.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Adeno_E3_CR2 PF02439.15 EIM84988.1 - 0.31 10.8 6.7 0.19 11.5 2.3 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 EIM84988.1 - 2 8.3 6.3 0.77 9.6 0.7 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF1708 PF08101.11 EIM84989.1 - 6.2e-19 68.5 0.0 4.2e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) Pro_isomerase PF00160.21 EIM84990.1 - 4.4e-47 160.3 0.4 5.1e-47 160.1 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF262 PF03235.14 EIM84991.1 - 9.8e-17 61.9 0.4 3.8e-16 59.9 0.1 2.1 2 1 1 3 3 3 1 Protein of unknown function DUF262 SMC_N PF02463.19 EIM84992.1 - 1.6e-66 223.9 0.0 9.1e-66 221.4 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIM84992.1 - 1.1e-20 74.1 0.6 5.3e-20 71.9 0.2 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EIM84992.1 - 8e-12 45.6 3.9 5.3e-05 23.2 0.2 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIM84992.1 - 1.5e-10 42.0 16.1 1.5e-10 42.0 16.1 6.6 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 EIM84992.1 - 7.6e-05 22.4 0.1 0.00021 21.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Atg14 PF10186.9 EIM84992.1 - 0.0033 16.6 22.7 0.0033 16.6 22.7 5.4 4 2 1 6 6 6 1 Vacuolar sorting 38 and autophagy-related subunit 14 CcdB PF01845.17 EIM84992.1 - 0.13 12.5 0.1 1 9.7 0.1 2.6 1 0 0 1 1 1 0 CcdB protein ABC_tran PF00005.27 EIM84992.1 - 0.18 12.3 0.0 0.18 12.3 0.0 5.7 2 2 1 3 3 3 0 ABC transporter Spc7 PF08317.11 EIM84992.1 - 0.41 9.5 117.3 0.017 14.0 3.9 6.6 3 3 3 6 6 6 0 Spc7 kinetochore protein EPO_TPO PF00758.18 EIM84992.1 - 2.7 8.0 6.9 0.33 11.0 0.7 2.7 2 1 0 3 3 3 0 Erythropoietin/thrombopoietin Peptidase_S32 PF05579.13 EIM84993.1 - 0.00062 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S3 PF00944.19 EIM84993.1 - 0.0042 16.9 0.1 0.0082 16.0 0.1 1.4 1 0 0 1 1 1 1 Alphavirus core protein PMM PF03332.13 EIM84993.1 - 0.045 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase Trypsin_2 PF13365.6 EIM84993.1 - 0.052 14.4 0.3 5.8 7.8 0.1 2.7 2 1 0 2 2 2 0 Trypsin-like peptidase domain Peptidase_S7 PF00949.21 EIM84993.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Polysacc_deac_1 PF01522.21 EIM84995.1 - 9e-27 93.4 0.0 3.3e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase IMUP PF15761.5 EIM84995.1 - 0.89 10.3 5.4 1.8 9.3 5.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Secretin_N_2 PF07655.13 EIM84995.1 - 1.3 9.6 12.5 6.1 7.5 0.0 2.6 3 0 0 3 3 3 0 Secretin N-terminal domain Inositol_P PF00459.25 EIM84996.1 - 2.8e-47 161.5 0.0 1e-46 159.6 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family p450 PF00067.22 EIM84997.1 - 2.4e-61 207.9 0.0 8.6e-61 206.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 EIM84998.1 - 3.9e-21 75.0 20.0 3.8e-05 24.4 0.5 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM84998.1 - 4.8e-08 33.2 3.7 0.075 13.3 0.1 4.7 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM84998.1 - 3.8e-06 26.1 0.2 0.051 12.5 0.0 3.4 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein GTP_EFTU PF00009.27 EIM84999.1 - 2.8e-58 196.7 1.6 3.8e-58 196.2 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EIM84999.1 - 1.1e-36 125.2 0.3 1.2e-35 121.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 EIM84999.1 - 3.5e-29 100.7 0.0 7.5e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EIM84999.1 - 2.4e-22 78.8 0.1 6.6e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EIM84999.1 - 2.1e-11 44.1 0.1 6.1e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EIM84999.1 - 2.6e-06 27.3 0.0 7.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain F-box-like PF12937.7 EIM85000.1 - 3e-11 43.0 0.9 6.3e-11 42.0 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM85000.1 - 0.0044 16.8 1.7 0.0051 16.6 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM85001.1 - 1.7e-15 56.6 0.3 3.1e-15 55.8 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM85001.1 - 9.9e-05 22.1 0.2 0.00039 20.2 0.2 2.1 1 1 0 1 1 1 1 F-box domain Rad10 PF03834.14 EIM85003.1 - 3.3e-45 152.7 0.1 4.5e-45 152.3 0.1 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EIM85003.1 - 3.3e-09 37.2 0.0 5.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EIM85003.1 - 0.0056 16.7 0.0 0.031 14.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 EIM85003.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_M48 PF01435.18 EIM85004.1 - 1e-27 97.2 0.0 2.6e-27 95.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 EIM85004.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF3337 PF11816.8 EIM85005.1 - 4.8e-50 169.8 0.0 9.2e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EIM85005.1 - 3.7e-20 71.9 20.8 3.6e-05 24.5 0.1 7.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 EIM85005.1 - 0.0016 17.2 0.7 0.062 11.9 0.0 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EIM85005.1 - 0.004 16.2 0.0 0.0093 15.0 0.0 1.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAWUL PF16207.5 EIM85005.1 - 0.019 15.6 0.1 0.039 14.6 0.1 1.4 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like ANAPC4_WD40 PF12894.7 EIM85005.1 - 0.026 14.8 0.0 0.32 11.3 0.1 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EIM85005.1 - 0.3 9.9 0.7 6.7 5.5 0.1 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain NAD_binding_9 PF13454.6 EIM85006.1 - 0.0052 16.8 0.0 0.032 14.2 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding NADHdh_A3 PF14987.6 EIM85008.1 - 0.073 13.4 0.2 0.074 13.4 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Pkinase PF00069.25 EIM85009.1 - 4.2e-07 29.6 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EIM85009.1 - 0.0016 17.3 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EIM85009.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3972 PF13118.6 EIM85009.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Pkinase PF00069.25 EIM85012.1 - 1.8e-06 27.6 0.0 0.00012 21.5 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85012.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase ATP-synt_J PF04911.12 EIM85012.1 - 0.081 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 ATP synthase j chain Pkinase PF00069.25 EIM85013.1 - 1.5e-07 31.1 0.0 2.8e-05 23.6 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85013.1 - 0.047 13.0 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase FMN_dh PF01070.18 EIM85014.1 - 7e-117 390.3 0.0 8.3e-117 390.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EIM85014.1 - 5.3e-20 71.4 0.0 2.5e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EIM85014.1 - 6.9e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EIM85014.1 - 0.0011 18.1 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain SR-25 PF10500.9 EIM85015.1 - 3.2 7.3 15.1 4.5 6.8 15.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tim17 PF02466.19 EIM85019.1 - 7.6e-33 113.2 2.8 9.2e-33 112.9 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 EIM85019.1 - 0.0018 18.2 1.3 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF543) APH PF01636.23 EIM85020.1 - 1.3e-20 74.3 2.0 1.7e-20 73.9 2.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM85020.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EIM85020.1 - 0.046 13.1 0.1 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIM85020.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 EIM85020.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 EIM85020.1 - 0.24 10.7 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RNase_PH PF01138.21 EIM85022.1 - 2.8e-20 73.2 0.0 4.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Cellulase PF00150.18 EIM85023.1 - 3.8e-31 108.5 0.1 6.2e-30 104.6 0.0 2.0 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) RSN1_7TM PF02714.15 EIM85025.1 - 1.9e-73 247.2 24.5 3.5e-73 246.3 24.5 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EIM85025.1 - 5e-37 127.1 0.2 5e-37 127.1 0.2 2.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EIM85025.1 - 1.2e-35 123.3 0.0 2e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CDC45 PF02724.14 EIM85026.1 - 0.006 14.9 7.6 0.0064 14.9 7.6 1.0 1 0 0 1 1 1 1 CDC45-like protein CPSF100_C PF13299.6 EIM85026.1 - 0.013 15.7 2.6 0.016 15.4 2.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_3_Rpc31 PF11705.8 EIM85026.1 - 0.016 15.5 11.6 0.023 15.0 11.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 EIM85026.1 - 0.05 13.3 10.2 0.065 12.9 10.2 1.2 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 EIM85026.1 - 0.057 12.8 12.2 0.063 12.7 12.2 1.0 1 0 0 1 1 1 0 SDA1 DUF4604 PF15377.6 EIM85026.1 - 0.058 13.8 11.5 0.068 13.6 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Radial_spoke PF04712.12 EIM85026.1 - 0.082 11.8 14.7 0.093 11.7 14.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4746 PF15928.5 EIM85026.1 - 0.12 11.7 13.8 0.15 11.5 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 EIM85026.1 - 0.18 10.0 13.2 0.19 9.9 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 EIM85026.1 - 0.23 11.3 9.9 0.28 11.1 9.9 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 EIM85026.1 - 0.25 10.6 10.0 0.3 10.4 10.0 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EIM85026.1 - 0.34 10.9 7.6 0.4 10.7 7.6 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal RPA43_OB PF17875.1 EIM85026.1 - 0.34 11.5 6.0 0.39 11.4 6.0 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PBP1_TM PF14812.6 EIM85026.1 - 0.35 11.3 10.8 0.49 10.8 10.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PS-DH PF14765.6 EIM85026.1 - 0.38 9.9 3.6 0.44 9.7 3.6 1.0 1 0 0 1 1 1 0 Polyketide synthase dehydratase Myc_N PF01056.18 EIM85026.1 - 0.57 10.0 11.2 0.87 9.4 11.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Paf1 PF03985.13 EIM85026.1 - 0.67 8.9 16.9 0.72 8.8 16.9 1.0 1 0 0 1 1 1 0 Paf1 Trypan_PARP PF05887.11 EIM85026.1 - 0.79 9.7 13.9 1.3 9.0 13.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 EIM85026.1 - 0.81 7.7 13.8 0.81 7.7 13.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 EIM85026.1 - 0.84 8.3 5.3 0.93 8.2 5.3 1.0 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 EIM85026.1 - 0.89 7.6 5.8 0.96 7.4 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Afi1 PF07792.12 EIM85026.1 - 0.91 10.0 4.7 1.1 9.7 4.7 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pox_Ag35 PF03286.14 EIM85026.1 - 1.1 9.0 11.7 1.3 8.8 11.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GOLD_2 PF13897.6 EIM85026.1 - 1.5 9.4 8.8 1.8 9.0 8.8 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CENP-B_dimeris PF09026.10 EIM85026.1 - 1.5 9.2 11.0 2.2 8.7 11.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TLP-20 PF06088.11 EIM85026.1 - 1.7 8.5 4.5 1.9 8.3 4.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Auts2 PF15336.6 EIM85026.1 - 1.7 8.7 8.8 1.9 8.6 8.8 1.0 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Cnd2 PF05786.14 EIM85026.1 - 1.8 7.1 10.2 2 7.0 10.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 PBP_sp32 PF07222.12 EIM85026.1 - 1.9 7.9 10.1 2.1 7.8 10.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF913 PF06025.12 EIM85026.1 - 2.1 7.2 5.0 2.4 7.1 5.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 EIM85026.1 - 2.2 7.4 9.0 2.6 7.2 9.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Eapp_C PF10238.9 EIM85026.1 - 2.2 8.3 7.1 2.7 8.1 7.1 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4820 PF16091.5 EIM85026.1 - 2.3 7.5 7.2 2.7 7.3 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 EIM85026.1 - 3 7.6 13.2 3.5 7.4 13.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 EIM85026.1 - 3.4 5.3 7.5 3.9 5.1 7.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4637 PF15470.6 EIM85026.1 - 3.4 7.4 16.9 4.5 7.0 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TFB6 PF17110.5 EIM85026.1 - 3.4 7.4 7.4 4.1 7.1 7.4 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF1840 PF08895.11 EIM85026.1 - 3.5 8.0 8.3 4.4 7.7 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Zip PF02535.22 EIM85026.1 - 4.2 6.5 4.2 4.5 6.4 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Fmp27 PF10344.9 EIM85026.1 - 4.4 5.3 4.9 4.4 5.3 4.9 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 G0-G1_switch_2 PF15103.6 EIM85026.1 - 5.4 7.5 8.7 6.7 7.2 8.7 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Serinc PF03348.15 EIM85026.1 - 6.3 5.6 5.5 7.8 5.3 5.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 EIM85026.1 - 6.4 6.5 7.6 7.3 6.3 7.6 1.1 1 0 0 1 1 1 0 Connexin AAA_11 PF13086.6 EIM85026.1 - 8.8 6.0 7.1 10 5.8 7.1 1.0 1 0 0 1 1 1 0 AAA domain DAGK_cat PF00781.24 EIM85028.1 - 1.7e-24 85.8 0.0 2.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain 2-Hacid_dh_C PF02826.19 EIM85029.1 - 1.1e-48 165.0 0.0 1.5e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM85029.1 - 4.5e-19 68.4 0.0 5.5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EIM85029.1 - 0.0024 17.2 0.0 0.0072 15.6 0.0 1.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EIM85029.1 - 0.0024 18.0 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EIM85029.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hydr_30_2 PF14587.6 EIM85030.1 - 7.9e-23 81.6 0.0 2.4e-21 76.7 0.0 2.1 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 DAO PF01266.24 EIM85031.1 - 1.1e-38 133.8 0.3 1.3e-38 133.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM85031.1 - 7.6e-06 26.1 0.0 3.3e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIM85031.1 - 3.5e-05 23.3 0.0 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EIM85031.1 - 9.8e-05 21.7 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EIM85031.1 - 0.00024 21.2 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EIM85031.1 - 0.0011 18.9 0.1 0.053 13.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIM85031.1 - 0.0026 16.9 0.2 0.015 14.4 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EIM85031.1 - 0.0029 16.9 0.0 0.0063 15.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM85031.1 - 0.0061 15.7 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 EIM85031.1 - 0.0084 16.6 0.0 0.16 12.6 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM85031.1 - 0.014 14.2 0.0 0.78 8.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glu_dehyd_C PF16912.5 EIM85031.1 - 0.034 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GMC_oxred_N PF00732.19 EIM85031.1 - 0.035 13.5 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.19 EIM85031.1 - 0.044 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Toprim_Crpt PF13342.6 EIM85031.1 - 0.055 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Sacchrp_dh_NADP PF03435.18 EIM85031.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 EIM85031.1 - 0.086 12.1 0.1 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 EIM85031.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 EIM85031.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EIM85031.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EIM85031.1 - 0.21 11.5 0.0 0.44 10.4 0.0 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EIM85032.1 - 3.5e-52 176.4 0.0 4.7e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM85032.1 - 9.3e-16 57.7 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIM85032.1 - 2.7e-05 24.4 0.0 5.6e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EIM85032.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 EIM85032.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1917 PF08939.10 EIM85033.1 - 5.6e-19 69.1 0.0 5.6e-19 69.1 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) Lyase_aromatic PF00221.19 EIM85034.1 - 1.9e-147 491.7 2.7 2.5e-147 491.3 2.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.25 EIM85036.1 - 1.4e-40 138.9 0.4 1.8e-40 138.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM85036.1 - 4.1e-31 108.3 0.5 5.3e-31 108.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM85036.1 - 6.9e-12 45.6 0.5 1.3e-11 44.7 0.4 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EIM85036.1 - 4.4e-07 29.3 0.1 5.2e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EIM85036.1 - 1.9e-06 27.5 0.2 2.7e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM85036.1 - 0.0034 16.4 0.1 0.0045 16.0 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 EIM85036.1 - 0.0042 17.5 0.9 0.013 16.0 0.9 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding PRMT5 PF05185.16 EIM85036.1 - 0.03 14.2 0.0 0.11 12.3 0.0 1.8 1 1 1 2 2 2 0 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.6 EIM85036.1 - 0.051 14.3 0.1 0.1 13.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EIM85036.1 - 0.068 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM85036.1 - 0.38 10.6 3.9 1.2 9.0 3.9 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Rer1 PF03248.13 EIM85038.1 - 7e-76 253.7 3.8 8.2e-76 253.5 3.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 EIM85038.1 - 0.048 13.3 3.0 0.097 12.3 3.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) SKG6 PF08693.10 EIM85040.1 - 0.0029 17.0 4.2 0.0065 15.9 4.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AAA_16 PF13191.6 EIM85041.1 - 0.00087 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EIM85041.1 - 0.0037 17.2 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Torsin PF06309.11 EIM85041.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_30 PF13604.6 EIM85041.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EIM85041.1 - 0.03 14.2 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 EIM85041.1 - 0.045 13.5 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EIM85041.1 - 0.05 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EIM85041.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EIM85041.1 - 0.071 13.3 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EIM85041.1 - 0.073 12.6 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EIM85041.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 EIM85041.1 - 0.095 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EIM85041.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EIM85041.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EIM85041.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 EIM85041.1 - 0.22 10.7 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF4576 PF15144.6 EIM85042.1 - 0.021 14.7 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) zf-MYND PF01753.18 EIM85043.1 - 1.8e-10 40.7 11.8 2.6e-10 40.2 11.8 1.2 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM85043.1 - 0.23 11.8 11.3 0.39 11.1 11.3 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Fcf1 PF04900.12 EIM85044.1 - 5.4e-37 126.2 1.0 9.8e-37 125.3 1.0 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EIM85044.1 - 1.3e-10 41.6 0.2 3.5e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 PIN like domain Proteasome_A_N PF10584.9 EIM85048.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature SdpI PF13630.6 EIM85048.1 - 0.055 13.6 9.3 1.1 9.4 0.6 3.3 2 1 0 2 2 2 0 SdpI/YhfL protein family RNase_T PF00929.24 EIM85049.1 - 2.7e-29 102.8 0.0 3.2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EIM85049.1 - 0.00019 21.5 0.2 0.00029 20.9 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Ank_4 PF13637.6 EIM85050.1 - 0.00051 20.5 2.1 0.15 12.7 0.1 4.7 5 3 2 7 7 7 2 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.14 EIM85050.1 - 1.3 8.9 0.0 1.3 8.9 0.0 4.6 5 1 1 6 6 6 0 hAT family C-terminal dimerisation region SWIB PF02201.18 EIM85051.1 - 2.8e-26 91.2 0.6 4.7e-26 90.5 0.6 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EIM85051.1 - 0.0006 19.7 0.1 0.0026 17.6 0.1 2.2 1 1 0 1 1 1 1 DEK C terminal domain AAA_16 PF13191.6 EIM85053.1 - 0.13 12.6 2.0 5.5 7.3 0.2 3.4 2 2 0 2 2 2 0 AAA ATPase domain RR_TM4-6 PF06459.12 EIM85053.1 - 1.1 9.1 6.4 1.8 8.3 6.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sel1 PF08238.12 EIM85055.1 - 2.3e-25 88.4 41.9 1.2e-05 25.8 0.4 10.4 9 2 1 10 10 10 6 Sel1 repeat TPR_1 PF00515.28 EIM85055.1 - 0.55 10.1 12.4 1.5 8.8 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM85055.1 - 4.5 7.3 6.8 13 5.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM85055.1 - 6.9 7.5 10.9 1.1e+02 3.7 1.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 EIM85056.1 - 1.6e-109 364.4 0.0 3.6e-83 278.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EIM85056.1 - 1e-39 135.6 0.1 2.3e-39 134.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EIM85056.1 - 4e-16 59.1 0.0 4.2e-08 33.0 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EIM85056.1 - 6.8e-12 45.4 0.0 7.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EIM85056.1 - 1.4e-11 44.3 0.0 0.00018 21.3 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EIM85056.1 - 1.9e-06 27.5 0.1 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 EIM85056.1 - 0.00071 19.7 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 EIM85056.1 - 0.0049 17.0 0.0 0.1 12.8 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain GARS_A PF01071.19 EIM85056.1 - 0.051 13.3 0.1 0.63 9.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Hydantoinase_B PF02538.14 EIM85058.1 - 1.4e-132 442.7 0.0 1.8e-132 442.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EIM85058.1 - 2.3e-89 299.5 0.4 2.3e-89 299.5 0.4 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EIM85058.1 - 4.2e-39 134.1 0.0 9.1e-37 126.5 0.0 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EIM85058.1 - 0.00045 18.9 0.1 0.017 13.8 0.2 2.2 2 0 0 2 2 2 2 MutL protein PDCD7 PF16021.5 EIM85059.1 - 4 6.5 27.0 7.6 5.6 27.0 1.5 1 1 0 1 1 1 0 Programmed cell death protein 7 V_ATPase_I PF01496.19 EIM85059.1 - 9 4.1 6.7 11 3.7 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NDUFA12 PF05071.16 EIM85060.1 - 0.024 15.5 0.2 0.024 15.5 0.2 2.0 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 THOC7 PF05615.13 EIM85061.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 zf-CCCH_2 PF14608.6 EIM85064.1 - 8.7e-10 38.7 27.4 9.8e-05 22.7 2.8 3.8 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EIM85064.1 - 3.9 7.4 11.3 13 5.8 0.1 3.9 3 0 0 3 3 3 0 CCCH-type zinc finger Spt20 PF12090.8 EIM85064.1 - 9.9 5.7 12.9 0.11 12.1 4.8 1.7 2 0 0 2 2 2 0 Spt20 family Cyclin_N PF00134.23 EIM85065.1 - 9.1e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EIM85065.1 - 4.7e-06 27.1 0.0 4.7e-06 27.1 0.0 2.2 2 1 0 2 2 2 1 Cyclin SOG2 PF10428.9 EIM85065.1 - 3.5 6.7 12.4 6.1 5.9 12.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_16 PF13191.6 EIM85068.1 - 0.0036 17.7 0.0 0.011 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Vasohibin PF14822.6 EIM85068.1 - 0.08 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Vasohibin DnaI_N PF07319.11 EIM85068.1 - 0.15 12.8 0.0 15 6.3 0.0 2.6 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Acetyltransf_1 PF00583.25 EIM85069.1 - 5.5e-06 26.6 0.0 8.1e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EIM85069.1 - 0.00093 19.9 0.1 0.0015 19.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM85069.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM85070.1 - 5.4e-05 23.4 0.1 8.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EIM85070.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EIM85070.1 - 0.11 13.1 0.1 0.18 12.5 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NMO PF03060.15 EIM85071.1 - 1.8e-25 90.1 0.5 1.8e-25 90.1 0.5 2.8 3 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 EIM85071.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DPBB_1 PF03330.18 EIM85072.1 - 9.7e-08 32.2 0.1 2.3e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM85072.1 - 0.0059 16.4 0.3 0.0098 15.7 0.1 1.4 1 1 0 1 1 1 1 Barwin family zinc_ribbon_2 PF13240.6 EIM85072.1 - 1 9.1 4.4 13 5.6 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain F-box-like PF12937.7 EIM85073.1 - 4.2e-08 33.0 0.1 1.3e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM85073.1 - 3.2e-06 26.9 0.0 3.2e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 EIM85073.1 - 0.53 11.0 3.5 13 6.8 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EIM85073.1 - 4.9 7.5 6.7 0.83 9.9 0.1 2.8 3 0 0 3 3 3 0 Leucine Rich repeat AMP-binding PF00501.28 EIM85074.1 - 4.4e-87 292.4 0.0 5.7e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM85074.1 - 2.1e-12 47.9 0.8 6.8e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NMO PF03060.15 EIM85075.1 - 2.9e-33 115.7 2.9 6.8e-32 111.1 2.9 2.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EIM85075.1 - 2.4e-09 36.6 0.0 0.0019 17.3 0.0 2.7 1 1 2 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EIM85075.1 - 0.0078 15.4 0.4 0.012 14.7 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 EIM85075.1 - 0.01 14.9 0.5 0.01 14.9 0.5 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 EIM85075.1 - 0.13 11.7 0.1 1.4 8.3 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein MFS_1 PF07690.16 EIM85076.1 - 2.4e-28 99.1 19.3 2.5e-24 85.9 9.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 EIM85076.1 - 0.00047 19.9 0.0 0.00089 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIM85076.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BcrAD_BadFG PF01869.20 EIM85077.1 - 3.9e-16 59.3 0.0 5.5e-09 35.9 0.0 2.8 1 1 1 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EIM85077.1 - 0.074 12.5 0.0 0.51 9.8 0.0 2.4 3 1 0 3 3 3 0 ROK family MFS_1 PF07690.16 EIM85079.1 - 0.00049 19.1 26.2 0.21 10.4 20.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 EIM85080.1 - 3.5e-08 33.2 0.2 9.6e-08 31.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like Cornichon PF03311.14 EIM85081.1 - 5.8e-53 178.4 11.2 6.7e-53 178.2 11.2 1.0 1 0 0 1 1 1 1 Cornichon protein Abhydrolase_3 PF07859.13 EIM85082.1 - 1e-46 159.4 0.0 1.8e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM85082.1 - 2.3e-12 46.6 0.0 4.5e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 EIM85082.1 - 0.0048 16.6 0.4 2.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Putative esterase Peptidase_S9 PF00326.21 EIM85082.1 - 0.045 13.2 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 EIM85082.1 - 0.085 12.4 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EIM85082.1 - 0.4 11.3 3.6 0.17 12.5 0.7 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family DAO PF01266.24 EIM85083.1 - 3.5e-36 125.5 0.0 4.3e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM85083.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Epimerase PF01370.21 EIM85083.1 - 0.098 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM85083.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.16 EIM85085.1 - 1.1e-16 60.8 37.3 1.1e-16 60.8 37.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85085.1 - 1.1e-07 31.1 8.3 1.1e-07 31.1 8.3 3.7 2 1 1 3 3 3 1 Sugar (and other) transporter UNC-93 PF05978.16 EIM85085.1 - 2.8e-07 30.4 3.0 2.8e-07 30.4 3.0 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 RNase_T PF00929.24 EIM85086.1 - 3.4e-13 50.5 0.0 4.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EIM85086.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease FtsJ PF01728.19 EIM85087.1 - 3.1e-15 56.7 0.0 4.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase FtsJ PF01728.19 EIM85088.1 - 7.8e-14 52.2 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EIM85088.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EIM85089.1 - 6.5e-18 65.5 0.0 1.1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NAD_kinase PF01513.21 EIM85090.1 - 7.5e-63 212.4 0.0 9.1e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EIM85090.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain FAD_binding_7 PF03441.14 EIM85091.1 - 0.056 12.9 0.0 0.06 12.8 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase XPG_I_2 PF12813.7 EIM85092.1 - 3e-06 26.9 0.0 0.00048 19.7 0.0 3.2 3 0 0 3 3 3 1 XPG domain containing XPG_N PF00752.17 EIM85092.1 - 0.013 16.0 0.0 0.077 13.5 0.0 2.1 2 0 0 2 2 2 0 XPG N-terminal domain BRCT PF00533.26 EIM85094.1 - 0.0047 17.3 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EIM85094.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LPMO_10 PF03067.15 EIM85095.1 - 3.4e-05 24.6 0.0 8.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SPX PF03105.19 EIM85095.1 - 1.5 8.7 9.6 1.9 8.3 9.6 1.1 1 0 0 1 1 1 0 SPX domain LCAT PF02450.15 EIM85096.1 - 3.8e-77 260.1 0.0 9.5e-77 258.8 0.0 1.6 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase CPDase PF07823.11 EIM85097.1 - 5.3e-08 32.8 0.1 2.6e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein PARP PF00644.20 EIM85097.1 - 0.0012 18.4 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 EIM85098.1 - 3.2e-11 43.2 1.3 8.8e-08 32.0 0.2 2.5 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF2116 PF09889.9 EIM85098.1 - 0.075 13.0 0.7 0.22 11.5 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NAP PF00956.18 EIM85099.1 - 1.6e-43 148.9 0.0 2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Ion_trans PF00520.31 EIM85100.1 - 1.5e-20 73.5 20.0 1.9e-20 73.1 20.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EIM85100.1 - 4.7e-13 48.9 4.8 4.7e-13 48.9 4.8 2.1 2 1 1 3 3 3 1 Ion channel Lig_chan PF00060.26 EIM85100.1 - 0.00072 19.4 0.5 0.00072 19.4 0.5 1.7 2 0 0 2 2 2 1 Ligand-gated ion channel TBD PF12845.7 EIM85100.1 - 0.15 12.0 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 TBD domain HTH_32 PF13565.6 EIM85100.1 - 0.18 12.5 0.2 2.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DUF962 PF06127.11 EIM85100.1 - 7.2 6.8 7.3 40 4.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Solute_trans_a PF03619.16 EIM85102.1 - 7.1e-85 284.7 17.2 8.6e-85 284.5 17.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3332 PF11810.8 EIM85102.1 - 0.021 14.4 1.0 0.04 13.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Pkinase PF00069.25 EIM85103.1 - 7.2e-71 238.6 0.0 8.7e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85103.1 - 1.3e-31 109.8 0.0 2.1e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM85103.1 - 0.013 14.5 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EIM85103.1 - 0.029 13.7 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM85103.1 - 0.038 13.9 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family S1FA PF04689.13 EIM85104.1 - 0.2 11.8 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA Tetraspanin PF00335.20 EIM85104.1 - 2.3 7.9 5.5 2.4 7.8 4.3 1.4 1 1 0 1 1 1 0 Tetraspanin family PH PF00169.29 EIM85106.1 - 7.8e-07 29.6 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Trep_Strep PF09605.10 EIM85107.1 - 0.00015 21.8 4.2 0.00024 21.1 4.3 1.4 1 1 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) 2TM PF13239.6 EIM85107.1 - 0.049 13.9 4.3 0.53 10.6 0.1 2.4 2 0 0 2 2 2 0 2TM domain CrgA PF06781.12 EIM85107.1 - 0.069 13.2 0.6 0.069 13.2 0.6 2.3 1 1 1 2 2 2 0 Cell division protein CrgA Cation_efflux PF01545.21 EIM85107.1 - 0.09 12.5 5.1 0.68 9.6 3.5 2.5 1 1 0 1 1 1 0 Cation efflux family HKR_ArcB_TM PF18415.1 EIM85107.1 - 0.13 13.0 4.4 0.57 11.0 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain ABC2_membrane_2 PF12679.7 EIM85107.1 - 0.17 11.1 3.9 0.25 10.6 3.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4149 PF13664.6 EIM85107.1 - 0.17 12.2 4.9 0.19 12.1 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) UPF0016 PF01169.19 EIM85107.1 - 0.35 11.2 3.9 2.5 8.5 1.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Aminotran_5 PF00266.19 EIM85108.1 - 3.1e-15 56.0 0.0 6.9e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EIM85108.1 - 0.00015 21.2 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EIM85108.1 - 0.048 12.8 0.1 0.21 10.7 0.1 1.8 1 1 0 1 1 1 0 Aminotransferase class I and II AvrL567-A PF11529.8 EIM85108.1 - 0.12 12.6 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Melampsora lini avirulence protein AvrL567-A zf-MYND PF01753.18 EIM85110.1 - 2.2e-08 34.0 10.1 2.2e-08 34.0 10.1 1.6 2 0 0 2 2 2 1 MYND finger CTU2 PF10288.9 EIM85110.1 - 0.017 15.4 0.7 0.031 14.5 0.7 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Pkinase PF00069.25 EIM85111.1 - 3e-33 115.3 0.0 2.7e-30 105.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85111.1 - 2.2e-17 63.2 0.1 2.1e-13 50.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIM85111.1 - 2.6e-05 24.3 0.0 0.00054 20.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM85111.1 - 0.0022 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIM85111.1 - 0.0082 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Acid_PPase PF12689.7 EIM85112.1 - 6.8e-61 205.0 0.0 7.7e-61 204.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase RHH_3 PF12651.7 EIM85112.1 - 0.087 12.8 0.1 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain Glyco_hydro_28 PF00295.17 EIM85113.1 - 1.4e-60 205.1 14.0 1.8e-60 204.8 14.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf-MYND PF01753.18 EIM85114.1 - 2.3e-08 34.0 0.3 2.3e-08 34.0 0.3 1.6 2 0 0 2 2 2 1 MYND finger adh_short PF00106.25 EIM85115.1 - 1.1e-35 122.9 0.0 1.6e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM85115.1 - 3e-22 79.3 0.0 4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase OPT PF03169.15 EIM85116.1 - 2.1e-178 594.8 53.7 2.4e-178 594.6 53.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Patatin PF01734.22 EIM85117.1 - 9.2e-23 81.5 0.0 1.6e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase F-box-like PF12937.7 EIM85118.1 - 0.0014 18.5 0.0 0.12 12.3 0.0 3.3 3 0 0 3 3 3 1 F-box-like FAD_binding_3 PF01494.19 EIM85119.1 - 7.7e-23 81.3 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM85119.1 - 2.5e-06 27.0 0.8 0.0012 18.1 1.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM85119.1 - 2.8e-06 27.5 1.4 1.2e-05 25.5 1.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM85119.1 - 9.9e-05 22.1 10.6 0.1 12.2 0.0 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM85119.1 - 0.00024 20.3 9.6 0.00094 18.4 7.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EIM85119.1 - 0.00028 21.4 1.6 0.068 13.7 1.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM85119.1 - 0.00094 18.1 1.8 0.084 11.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 EIM85119.1 - 0.0021 16.8 3.0 0.014 14.1 2.9 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EIM85119.1 - 0.042 13.1 1.2 0.079 12.2 1.2 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 EIM85119.1 - 0.052 12.8 1.5 8.2 5.6 1.2 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EIM85119.1 - 0.19 11.0 1.5 0.39 10.0 1.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EIM85119.1 - 0.28 10.5 7.7 0.45 9.8 7.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM85119.1 - 0.33 9.9 1.3 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EIM85119.1 - 1.2 8.2 6.8 1.8 7.5 6.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EIM85119.1 - 6.9 5.8 6.4 11 5.1 6.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Evr1_Alr PF04777.13 EIM85120.1 - 9.3e-27 93.4 0.1 1.3e-26 93.0 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family LSM PF01423.22 EIM85121.1 - 2.1e-16 59.4 0.1 2.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain Amidase PF01425.21 EIM85123.1 - 4e-34 118.4 1.6 4e-34 118.4 1.6 1.6 2 0 0 2 2 2 1 Amidase Amidase PF01425.21 EIM85124.1 - 2e-33 116.0 1.3 2e-33 116.0 1.3 2.2 3 0 0 3 3 3 1 Amidase DUF3040 PF11239.8 EIM85125.1 - 0.43 10.9 6.2 0.085 13.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) TMEM61 PF15105.6 EIM85125.1 - 8.8 6.1 8.5 1.1 9.0 3.5 2.0 2 0 0 2 2 2 0 TMEM61 protein family MIF4G PF02854.19 EIM85126.1 - 2.8e-58 197.1 0.7 5.2e-58 196.2 0.7 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EIM85126.1 - 3.4e-20 72.0 0.0 1e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 EIM85126.1 - 1.3e-07 31.5 0.1 4.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 MA3 domain LCM PF04072.14 EIM85127.1 - 2.9e-23 82.8 0.0 5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TrkH PF02386.16 EIM85128.1 - 1.8e-58 198.2 7.1 1.8e-33 115.7 0.1 3.1 2 1 1 3 3 3 3 Cation transport protein Hum_adeno_E3A PF05393.11 EIM85128.1 - 0.015 15.2 4.6 1.6 8.8 0.4 3.7 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein TrkH PF02386.16 EIM85129.1 - 1.4e-22 79.9 0.0 2.1e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Cation transport protein TPT PF03151.16 EIM85130.1 - 7.6e-32 110.8 8.5 3.7e-23 82.3 3.1 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EIM85130.1 - 6.3e-06 26.4 26.7 9.1e-06 25.9 8.0 3.0 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EIM85130.1 - 1.3e-05 24.6 12.3 6e-05 22.4 2.4 2.4 2 1 0 2 2 2 2 UAA transporter family Redoxin PF08534.10 EIM85131.1 - 4.9e-27 94.5 0.1 5.8e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EIM85131.1 - 4e-14 52.6 0.0 5.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family SNN_cytoplasm PF09051.10 EIM85131.1 - 0.0052 16.6 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Stannin cytoplasmic DUF824 PF05688.11 EIM85131.1 - 0.017 14.9 1.0 0.053 13.3 0.1 2.2 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Mid1 PF12929.7 EIM85132.1 - 3.3e-57 194.6 0.1 4.4e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EIM85132.1 - 0.026 15.1 4.2 0.86 10.2 0.6 2.5 2 0 0 2 2 2 0 Fz domain Cellulase PF00150.18 EIM85133.1 - 2.2e-31 109.4 1.4 3.6e-31 108.6 1.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Keratin_2_head PF16208.5 EIM85135.1 - 0.35 11.0 10.1 1 9.5 10.1 1.8 1 0 0 1 1 1 0 Keratin type II head DUF21 PF01595.20 EIM85136.1 - 7.5e-34 116.9 0.4 1.2e-33 116.3 0.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain TIMELESS_C PF05029.13 EIM85136.1 - 0.02 14.0 0.7 0.04 13.1 0.7 1.4 1 0 0 1 1 1 0 Timeless protein C terminal region ARD PF03079.14 EIM85137.1 - 8.2e-45 152.8 0.0 9.8e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EIM85137.1 - 6.2e-10 38.6 0.6 1.1e-09 37.8 0.1 1.7 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 EIM85137.1 - 2.2e-06 27.6 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EIM85137.1 - 0.0098 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EIM85137.1 - 0.012 15.3 0.1 0.078 12.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF861) Arrestin_C PF02752.22 EIM85139.1 - 9.1e-16 58.5 0.0 3.3e-13 50.2 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EIM85139.1 - 5.9e-12 45.9 0.0 2.9e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain ICMT PF04140.14 EIM85140.1 - 1.7e-14 54.0 0.8 2.1e-12 47.3 0.2 2.5 2 0 0 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM85140.1 - 4.6e-12 46.3 2.9 8.2e-11 42.2 0.3 2.3 2 0 0 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM85140.1 - 2.3e-05 23.4 0.7 3.3e-05 22.8 0.7 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Pkinase PF00069.25 EIM85144.1 - 6.6e-21 74.8 0.0 7.8e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EIM85144.1 - 1.5e-09 37.2 0.4 2e-09 36.8 0.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EIM85144.1 - 1.9e-08 33.9 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM85144.1 - 0.0098 15.8 0.2 0.026 14.5 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L14e PF01929.17 EIM85145.1 - 4e-30 104.1 0.2 5.9e-30 103.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EIM85145.1 - 2.9e-06 27.0 0.2 2.9e-06 27.0 0.2 1.9 3 0 0 3 3 3 1 KOW motif CHAP PF05257.16 EIM85145.1 - 0.15 12.7 0.3 0.26 11.9 0.1 1.6 2 0 0 2 2 2 0 CHAP domain CwsA PF10814.8 EIM85147.1 - 1.5 9.0 11.1 0.85 9.8 6.2 2.2 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Ribosomal_S10 PF00338.22 EIM85148.1 - 6.5e-24 84.0 0.0 1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Mago_nashi PF02792.14 EIM85149.1 - 7.8e-75 249.7 0.2 8.8e-75 249.6 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF4451 PF14616.6 EIM85150.1 - 3.4e-32 111.2 0.8 4e-32 111.0 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) EMP24_GP25L PF01105.24 EIM85151.1 - 3.1e-45 154.4 0.0 3.5e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 EIM85151.1 - 0.0042 17.5 0.5 0.007 16.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) tRNA-synt_1 PF00133.22 EIM85152.1 - 6.8e-217 721.5 0.0 7.5e-216 718.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EIM85152.1 - 5e-32 111.0 0.1 9.9e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EIM85152.1 - 3.9e-15 55.5 0.0 6.6e-07 28.4 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EIM85152.1 - 1.5e-10 40.9 0.1 8.4e-07 28.7 0.1 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EIM85152.1 - 0.0068 15.8 0.0 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Cpn60_TCP1 PF00118.24 EIM85153.1 - 1.2e-85 288.1 6.2 2e-85 287.3 6.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family NAD_binding_8 PF13450.6 EIM85154.1 - 1.6e-15 57.0 0.0 6.8e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM85154.1 - 4.9e-08 32.9 0.0 4.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EIM85154.1 - 1.5e-05 24.5 0.0 3.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EIM85154.1 - 2.9e-05 23.4 0.0 5.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EIM85154.1 - 8e-05 22.7 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIM85154.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EIM85154.1 - 0.00025 21.5 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM85154.1 - 0.00063 19.1 0.0 0.0084 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM85154.1 - 0.0047 15.7 0.0 0.0084 14.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EIM85154.1 - 0.012 15.0 0.1 0.028 13.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIM85154.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EIM85154.1 - 0.12 11.6 0.0 0.53 9.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SpoIIE PF07228.12 EIM85156.1 - 0.00063 19.7 0.0 0.0053 16.7 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EIM85156.1 - 0.0018 18.0 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EIM85156.1 - 0.018 14.7 0.1 0.091 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C DUF5102 PF17104.5 EIM85156.1 - 8 6.4 7.0 1.2 9.2 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) BAR_2 PF10455.9 EIM85157.1 - 5.5e-48 163.6 2.3 2e-47 161.7 2.3 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EIM85157.1 - 1.8e-20 73.6 2.8 7e-20 71.7 2.8 1.8 1 1 0 1 1 1 1 BAR domain DALR_1 PF05746.15 EIM85157.1 - 0.0088 16.2 5.3 0.015 15.4 0.6 2.4 1 1 1 2 2 2 1 DALR anticodon binding domain DUF4642 PF15484.6 EIM85157.1 - 0.14 12.4 0.6 0.27 11.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) HalX PF08663.10 EIM85157.1 - 0.37 11.1 6.0 0.81 10.0 0.2 3.5 4 0 0 4 4 4 0 HalX domain Uds1 PF15456.6 EIM85157.1 - 0.57 10.4 0.1 0.57 10.4 0.1 2.5 2 1 0 2 2 2 0 Up-regulated During Septation Proteasome PF00227.26 EIM85158.1 - 8.8e-49 165.6 0.2 1.1e-48 165.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EIM85158.1 - 6e-12 44.8 0.6 6e-12 44.8 0.6 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_C PF07479.14 EIM85158.1 - 0.061 13.6 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus CAP59_mtransfer PF11735.8 EIM85159.1 - 6.7e-37 127.5 0.0 1.2e-36 126.6 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Dimer_Tnp_hAT PF05699.14 EIM85163.1 - 1.2e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SDA1 PF05285.12 EIM85164.1 - 6.3 6.1 13.2 7.4 5.9 13.2 1.1 1 0 0 1 1 1 0 SDA1 DUF1030 PF06270.11 EIM85166.1 - 0.045 13.5 0.1 0.066 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) gag-asp_proteas PF13975.6 EIM85167.1 - 0.031 14.8 0.0 0.09 13.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Herpes_ORF11 PF04797.13 EIM85167.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus dUTPase protein DDE_Tnp_4 PF13359.6 EIM85172.1 - 5.8e-21 74.8 0.0 7.5e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease GerE PF00196.19 EIM85172.1 - 0.019 14.5 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family TetR_N PF00440.23 EIM85172.1 - 0.044 13.6 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Sigma70_r4_2 PF08281.12 EIM85172.1 - 0.046 13.4 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 EIM85172.1 - 0.065 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Retrotran_gag_2 PF14223.6 EIM85177.1 - 2.7e-20 72.4 0.6 3.2e-20 72.2 0.6 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.22 EIM85177.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DNA_pol_phi PF04931.13 EIM85181.1 - 0.86 7.6 7.2 1.5 6.8 7.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EIM85181.1 - 10 6.6 9.5 23 5.5 9.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4939 PF16297.5 EIM85183.1 - 4.7e-06 26.5 0.0 5.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Asp_protease PF09668.10 EIM85184.1 - 0.022 14.6 0.0 0.024 14.4 0.0 1.0 1 0 0 1 1 1 0 Aspartyl protease Glyco_hydro_61 PF03443.14 EIM85185.1 - 1.4e-48 165.6 0.0 1.8e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-Tim10_DDP PF02953.15 EIM85186.1 - 0.076 12.7 0.9 0.14 11.8 0.9 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF3583 PF12126.8 EIM85186.1 - 8.3 5.8 7.3 0.31 10.4 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3583) Pkinase PF00069.25 EIM85188.1 - 6.2e-32 111.0 0.0 7.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85188.1 - 1.7e-13 50.5 0.0 3.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM85188.1 - 0.003 17.5 0.0 0.0059 16.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM85188.1 - 0.0068 15.2 0.1 0.021 13.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Flavin_Reduct PF01613.18 EIM85190.1 - 4.8e-21 75.4 0.0 6.5e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain OPT PF03169.15 EIM85193.1 - 1.1e-73 248.9 35.9 1.4e-73 248.6 35.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GMC_oxred_N PF00732.19 EIM85194.1 - 1.7e-65 221.3 0.0 2.3e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM85194.1 - 1.5e-27 96.9 0.0 2.8e-26 92.8 0.0 2.3 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM85194.1 - 0.00046 20.4 0.7 0.00046 20.4 0.7 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM85194.1 - 0.0014 17.8 0.1 0.061 12.4 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 EIM85194.1 - 0.0025 16.9 0.1 0.0036 16.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EIM85194.1 - 0.0038 16.8 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM85194.1 - 0.018 14.3 0.1 0.039 13.2 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EIM85194.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HHH_5 PF14520.6 EIM85194.1 - 0.038 14.6 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HI0933_like PF03486.14 EIM85194.1 - 0.12 11.0 0.1 0.23 10.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EIM85194.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Oxidored_FMN PF00724.20 EIM85195.1 - 3.3e-82 276.5 0.0 3.8e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.19 EIM85196.1 - 4.6e-15 55.7 0.0 7.5e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM85196.1 - 2.1e-07 31.1 0.0 5.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM85196.1 - 1.4e-05 24.9 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM85196.1 - 1.8e-05 25.2 0.0 0.0099 16.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM85196.1 - 4.7e-05 22.7 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM85196.1 - 0.00012 21.5 0.0 0.009 15.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM85196.1 - 0.00088 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 EIM85196.1 - 0.0055 16.0 0.1 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EIM85196.1 - 0.0071 15.2 0.0 1.5 7.5 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 EIM85196.1 - 0.012 14.4 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EIM85196.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM85196.1 - 0.071 12.1 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EIM85196.1 - 0.086 12.8 0.2 0.91 9.5 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding ICMT PF04140.14 EIM85197.1 - 1.3e-11 44.7 3.7 1.9e-11 44.2 0.7 2.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM85197.1 - 2.1e-08 34.5 1.3 1e-07 32.3 0.6 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM85197.1 - 0.00095 18.0 0.8 0.00095 18.0 0.8 1.6 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Pox_A14 PF05767.12 EIM85197.1 - 0.22 11.7 2.4 0.37 11.0 0.2 2.4 2 2 1 3 3 3 0 Poxvirus virion envelope protein A14 Acyl-CoA_dh_M PF02770.19 EIM85198.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain DUF829 PF05705.14 EIM85199.1 - 1.9e-32 113.1 0.0 2.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DEAD PF00270.29 EIM85201.1 - 5.3e-19 68.6 0.0 9.6e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM85201.1 - 5.6e-13 49.2 0.0 7.1e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM85201.1 - 1.8e-06 28.1 0.2 4.4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EIM85201.1 - 0.0048 15.7 0.1 0.12 11.0 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain RecQ_Zn_bind PF16124.5 EIM85201.1 - 0.046 14.5 1.0 0.046 14.5 1.0 2.5 3 0 0 3 3 3 0 RecQ zinc-binding TIR PF01582.20 EIM85201.1 - 0.057 13.2 0.7 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 TIR domain Vpu PF00558.19 EIM85201.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.8 3 0 0 3 3 3 0 Vpu protein Ndc1_Nup PF09531.10 EIM85201.1 - 0.47 9.1 16.9 0.51 9.0 2.6 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 EIM85202.1 - 4.1e-09 36.2 0.0 7.8e-08 32.0 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85202.1 - 0.0018 17.7 0.0 0.04 13.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ste5 PF11610.8 EIM85202.1 - 0.13 12.2 1.9 0.57 10.1 0.3 2.6 2 0 0 2 2 2 0 Scaffold protein Ste5, Fus3-binding region Herpes_gE PF02480.16 EIM85203.1 - 0.063 12.0 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2678 PF10856.8 EIM85203.1 - 0.11 12.5 1.4 0.24 11.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) DUF4293 PF14126.6 EIM85203.1 - 0.44 10.8 3.7 1.3 9.2 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2070 PF09843.9 EIM85203.1 - 5.5 5.1 10.4 10 4.3 10.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Oxidored_FMN PF00724.20 EIM85205.1 - 3.4e-79 266.6 0.0 3.9e-79 266.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4534 PF15049.6 EIM85206.1 - 0.11 12.2 2.8 0.47 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) Pilosulin PF17499.2 EIM85206.1 - 9.3 6.5 6.3 37 4.6 0.2 3.2 3 1 1 4 4 4 0 Ant venom peptides dsrm PF00035.26 EIM85208.1 - 0.022 15.5 0.1 0.072 13.8 0.0 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif Trypan_PARP PF05887.11 EIM85208.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.5 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.22 EIM85210.1 - 8e-72 242.5 0.0 9.7e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_3 PF15421.6 EIM85210.1 - 0.052 12.1 0.0 0.08 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative polysaccharide deacetylase InPase PF18823.1 EIM85210.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Inorganic Pyrophosphatase MFS_1 PF07690.16 EIM85213.1 - 4.3e-35 121.3 29.9 5.9e-35 120.8 29.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Porphobil_deamC PF03900.15 EIM85215.1 - 9.5e-15 54.7 0.4 2.1e-14 53.7 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Porphobil_deam PF01379.20 EIM85215.1 - 1.2e-14 54.4 0.0 1.1e-13 51.2 0.0 2.2 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Umbravirus_LDM PF04817.12 EIM85215.1 - 0.055 12.8 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family NAD_binding_4 PF07993.12 EIM85216.1 - 2.4e-07 30.2 0.0 3.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EIM85216.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 EIM85217.1 - 2.1e-48 165.3 0.0 1.2e-47 162.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 EIM85218.1 - 4.6e-22 78.5 6.3 4.6e-22 78.5 6.3 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family p450 PF00067.22 EIM85219.1 - 2.8e-48 164.8 0.0 3.5e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM85220.1 - 1.8e-45 155.6 0.0 3.7e-45 154.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_10 PF13673.7 EIM85221.1 - 2.5e-07 30.7 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM85221.1 - 6.5e-06 26.5 0.0 1e-05 25.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM85221.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 EIM85221.1 - 0.018 14.6 0.0 0.082 12.5 0.0 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase FR47 PF08445.10 EIM85221.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.7 EIM85221.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease PF00324.21 EIM85224.1 - 1.1e-114 383.7 42.0 1.3e-114 383.5 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM85224.1 - 1.6e-32 112.9 46.3 2e-32 112.6 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease ICMT PF04140.14 EIM85225.1 - 4.1e-12 46.3 0.3 6.9e-12 45.6 0.2 1.5 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM85225.1 - 2.7e-09 37.4 0.9 1.8e-07 31.5 0.2 2.0 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM85225.1 - 0.00014 20.8 0.0 0.00017 20.5 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2142 PF09913.9 EIM85225.1 - 0.019 13.8 0.2 0.021 13.7 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) FA_desaturase PF00487.24 EIM85226.1 - 1.4e-21 77.5 37.4 1.4e-21 77.5 37.4 1.6 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EIM85226.1 - 0.048 13.9 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) p450 PF00067.22 EIM85228.1 - 3.6e-25 88.6 0.0 4.3e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM85229.1 - 5.3e-09 35.3 0.0 7.1e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EIM85230.1 - 3.1e-31 108.6 53.9 1e-30 106.9 53.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85230.1 - 5.5e-13 48.6 10.5 5.5e-13 48.6 10.5 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter HAP PF03866.13 EIM85230.1 - 0.12 12.4 6.2 0.24 11.4 2.1 2.5 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) Abhydrolase_6 PF12697.7 EIM85231.1 - 5.2e-14 53.4 0.1 7.5e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2716 PF10898.8 EIM85231.1 - 0.011 16.1 0.2 0.043 14.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) ICMT PF04140.14 EIM85232.1 - 8.7e-13 48.5 0.5 1.1e-12 48.2 0.5 1.4 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM85232.1 - 2e-09 37.8 1.6 4.4e-09 36.7 1.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM85232.1 - 7.2e-07 28.3 0.1 8.5e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIM85232.1 - 0.0036 16.9 0.1 0.0039 16.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3778 PF12620.8 EIM85233.1 - 0.041 13.5 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) DMAP1_like PF17024.5 EIM85233.1 - 0.044 13.9 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative DMAP1-like UPF0182 PF03699.13 EIM85233.1 - 0.17 10.0 1.4 0.3 9.2 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ICMT PF04140.14 EIM85234.1 - 1.2e-09 38.4 0.1 1.5e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM85234.1 - 3.8e-06 27.2 0.5 4.6e-06 27.0 0.5 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase MFS_1 PF07690.16 EIM85235.1 - 3.1e-09 36.2 13.6 3.6e-09 36.0 13.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85235.1 - 0.0013 17.7 7.4 0.0016 17.4 7.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter RVP_2 PF08284.11 EIM85236.1 - 0.013 15.3 0.5 0.033 13.9 0.5 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Helitron_like_N PF14214.6 EIM85238.1 - 2.1e-07 31.4 0.0 4.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EIM85239.1 - 0.0011 18.2 0.0 0.0012 18.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 EIM85239.1 - 0.04 14.3 0.1 0.051 14.0 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 EIM85240.1 - 0.00036 19.8 0.1 0.00052 19.3 0.1 1.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EIM85240.1 - 0.0054 16.5 0.0 0.073 12.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 EIM85241.1 - 0.094 11.9 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 PIF1-like helicase SH3_13 PF18335.1 EIM85241.1 - 0.13 12.2 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 EIM85242.1 - 0.0036 17.1 0.1 0.01 15.7 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain MFS_1 PF07690.16 EIM85244.1 - 1.4e-08 34.0 22.0 1.8e-08 33.7 22.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85244.1 - 0.03 13.2 16.4 0.034 13.0 16.4 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter ADH_zinc_N PF00107.26 EIM85245.1 - 4.6e-18 65.4 0.8 7.9e-18 64.7 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM85245.1 - 8e-15 56.1 0.0 1.9e-14 54.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM85245.1 - 6.6e-05 22.8 0.0 0.00087 19.2 0.0 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain dTDP_sugar_isom PF00908.17 EIM85245.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase FAD_binding_3 PF01494.19 EIM85246.1 - 6.3e-21 75.0 0.0 2.2e-20 73.2 0.0 1.7 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EIM85246.1 - 2.7e-08 33.9 0.3 5.6e-08 32.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM85246.1 - 2.7e-07 30.5 0.1 0.00013 21.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM85246.1 - 4.8e-07 29.2 0.1 7.1e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM85246.1 - 3.5e-05 23.2 0.0 0.00086 18.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM85246.1 - 4.2e-05 22.8 0.0 0.033 13.3 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 EIM85246.1 - 0.00012 20.9 0.0 0.0011 17.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EIM85246.1 - 0.00029 20.3 0.1 0.33 10.2 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 EIM85246.1 - 0.0091 15.1 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EIM85246.1 - 0.024 15.2 0.0 0.07 13.7 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM85246.1 - 0.029 13.7 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EIM85246.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM85246.1 - 0.063 13.3 0.0 0.44 10.5 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EIM85246.1 - 0.078 12.2 0.3 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 EIM85246.1 - 0.16 11.3 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 EIM85248.1 - 3.5e-40 138.0 43.4 7e-40 137.0 43.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM85248.1 - 2.3e-19 69.3 11.7 3.2e-19 68.8 11.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIM85248.1 - 8.7e-11 41.3 12.1 8.7e-11 41.3 12.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter HlyIII PF03006.20 EIM85248.1 - 0.018 14.8 1.4 0.018 14.8 1.4 2.9 3 1 0 3 3 3 0 Haemolysin-III related Thaumatin PF00314.17 EIM85249.1 - 5.1e-05 23.0 6.9 0.0059 16.3 0.2 3.2 2 1 2 4 4 4 2 Thaumatin family Macoilin PF09726.9 EIM85249.1 - 8.3 4.8 8.8 9.9 4.6 8.8 1.1 1 0 0 1 1 1 0 Macoilin family FAD_binding_3 PF01494.19 EIM85251.1 - 1.3e-14 54.2 0.0 2.2e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM85251.1 - 0.00092 19.4 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM85251.1 - 0.025 14.1 0.1 4 6.9 0.1 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIM85251.1 - 0.072 11.9 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_M20 PF01546.28 EIM85252.1 - 7.2e-31 107.5 0.0 1.8e-30 106.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM85252.1 - 6.7e-10 38.8 0.0 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF3328 PF11807.8 EIM85253.1 - 2.2e-16 60.3 0.5 5.3e-16 59.1 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) dsrm PF00035.26 EIM85260.1 - 0.06 14.1 0.2 0.17 12.6 0.2 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif F-box PF00646.33 EIM85261.1 - 5.6e-07 29.3 1.0 1.7e-06 27.8 1.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM85261.1 - 0.00088 19.1 0.7 0.0022 17.8 0.7 1.8 1 0 0 1 1 1 1 F-box-like DUF2947 PF11163.8 EIM85261.1 - 0.27 11.1 0.8 0.53 10.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DUF2939 PF11159.8 EIM85265.1 - 0.15 12.5 0.3 0.22 12.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Helitron_like_N PF14214.6 EIM85266.1 - 0.018 15.3 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Pes-10 PF07149.11 EIM85270.1 - 0.021 13.9 1.7 4.2 6.3 2.2 2.2 2 0 0 2 2 2 0 Pes-10 AAA PF00004.29 EIM85272.1 - 4.3e-40 137.2 1.1 3.7e-16 59.8 0.0 5.4 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 EIM85272.1 - 9.6e-39 133.1 0.0 2.5e-38 131.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM85272.1 - 1.7e-19 70.7 35.1 1.1e-15 58.1 0.0 7.4 6 1 0 6 6 5 2 AAA domain AAA_lid_6 PF17866.1 EIM85272.1 - 2.1e-17 63.0 0.0 6.1e-06 26.3 0.0 4.5 3 0 0 3 3 3 2 AAA lid domain AAA_30 PF13604.6 EIM85272.1 - 2.5e-16 60.0 6.5 0.0068 16.1 0.0 6.9 5 1 0 5 5 5 4 AAA domain AAA_5 PF07728.14 EIM85272.1 - 1.6e-11 44.3 3.7 0.22 11.5 0.1 5.9 4 1 1 5 5 5 3 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EIM85272.1 - 5e-11 43.1 10.0 0.39 11.0 0.0 6.9 7 1 0 7 7 6 3 AAA domain Viral_helicase1 PF01443.18 EIM85272.1 - 2.6e-10 40.4 7.9 0.014 15.2 0.0 6.6 7 1 0 7 7 7 3 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EIM85272.1 - 5.8e-10 39.1 0.6 0.086 12.6 0.0 4.7 4 0 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EIM85272.1 - 1.9e-08 34.0 1.5 0.62 9.4 0.0 4.5 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EIM85272.1 - 3.7e-07 30.5 20.9 0.22 11.8 0.0 8.3 6 2 0 7 7 7 2 AAA domain AAA_24 PF13479.6 EIM85272.1 - 6e-07 29.4 6.0 0.43 10.3 0.1 5.3 5 0 0 5 5 5 2 AAA domain Sigma54_activat PF00158.26 EIM85272.1 - 5.4e-06 26.2 0.7 4.8 6.8 0.0 4.9 5 0 0 5 5 5 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EIM85272.1 - 6.5e-06 26.0 0.3 4.3 7.0 0.0 5.1 6 0 0 6 6 4 1 IstB-like ATP binding protein AAA_16 PF13191.6 EIM85272.1 - 9.6e-06 26.1 18.2 0.28 11.6 0.0 6.0 6 0 0 6 6 4 3 AAA ATPase domain RNA_helicase PF00910.22 EIM85272.1 - 1.2e-05 25.6 1.4 6.8 7.1 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_33 PF13671.6 EIM85272.1 - 0.00011 22.4 15.6 0.32 11.2 0.1 5.4 5 0 0 5 5 4 2 AAA domain Torsin PF06309.11 EIM85272.1 - 0.00017 21.7 0.2 7.9 6.6 0.0 4.3 4 0 0 4 4 4 0 Torsin PhoH PF02562.16 EIM85272.1 - 0.00035 20.1 0.6 1.4 8.3 0.0 4.4 4 0 0 4 4 4 1 PhoH-like protein ResIII PF04851.15 EIM85272.1 - 0.0015 18.6 0.1 8.4 6.4 0.0 4.6 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EIM85272.1 - 0.0032 17.0 4.8 3.3 7.2 0.1 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region TsaE PF02367.17 EIM85272.1 - 0.0072 16.3 1.6 7.3 6.6 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EIM85272.1 - 0.0096 16.5 20.3 2.5 8.7 0.1 5.9 5 0 0 5 5 4 1 AAA domain DUF2075 PF09848.9 EIM85272.1 - 0.036 13.3 15.6 0.04 13.2 0.0 6.4 7 0 0 7 7 6 0 Uncharacterized conserved protein (DUF2075) ADK PF00406.22 EIM85272.1 - 0.042 14.0 3.2 7.5 6.6 0.1 4.0 3 0 0 3 3 3 0 Adenylate kinase MCM PF00493.23 EIM85272.1 - 0.063 12.4 0.3 0.61 9.1 0.0 2.5 2 0 0 2 2 2 0 MCM P-loop domain Rad17 PF03215.15 EIM85272.1 - 0.066 13.1 0.0 16 5.4 0.0 3.6 3 0 0 3 3 3 0 Rad17 P-loop domain NB-ARC PF00931.22 EIM85272.1 - 0.067 12.4 0.7 20 4.2 0.0 3.9 4 0 0 4 4 4 0 NB-ARC domain SRP54 PF00448.22 EIM85272.1 - 0.089 12.4 1.4 3.9 7.1 0.0 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_3 PF07726.11 EIM85272.1 - 0.11 12.4 0.2 86 3.0 0.0 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EIM85272.1 - 0.11 11.8 5.6 14 4.9 0.0 4.5 4 0 0 4 4 4 0 KaiC NTPase_1 PF03266.15 EIM85272.1 - 0.13 12.2 5.8 24 4.8 0.1 4.3 4 0 0 4 4 4 0 NTPase NACHT PF05729.12 EIM85272.1 - 0.32 10.9 6.5 59 3.5 0.1 4.7 5 0 0 5 5 4 0 NACHT domain ABC_tran PF00005.27 EIM85272.1 - 3.3 8.2 13.2 20 5.7 0.0 5.4 5 0 0 5 5 5 0 ABC transporter RsgA_GTPase PF03193.16 EIM85272.1 - 4.5 7.1 6.2 18 5.2 0.0 3.8 5 0 0 5 5 4 0 RsgA GTPase AAA_28 PF13521.6 EIM85272.1 - 6.9 6.9 24.1 1.3 9.3 0.1 6.0 5 1 1 6 6 4 0 AAA domain Dynamin_M PF01031.20 EIM85273.1 - 6.2e-10 38.8 0.0 0.00019 20.8 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 EIM85273.1 - 3.2e-09 37.1 0.0 6.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EIM85273.1 - 1.7e-05 24.9 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_N PF00350.23 EIM85274.1 - 1.2e-25 90.6 0.3 4e-25 88.8 0.3 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EIM85274.1 - 2e-23 83.0 0.0 1e-22 80.7 0.0 1.9 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EIM85274.1 - 2e-11 43.9 0.2 7e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EIM85274.1 - 0.00031 20.8 0.5 0.0031 17.6 0.5 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EIM85274.1 - 0.096 12.9 0.2 0.51 10.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Na_H_Exchanger PF00999.21 EIM85275.1 - 2.1e-35 122.2 39.0 1.4e-34 119.5 39.0 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Dynamin_N PF00350.23 EIM85276.1 - 4e-24 85.5 0.0 1.5e-23 83.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EIM85276.1 - 2.5e-22 79.4 0.0 6.8e-22 78.0 0.0 1.6 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EIM85276.1 - 3.5e-11 43.1 0.0 9.4e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EIM85276.1 - 0.00016 21.8 0.3 0.0026 17.8 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gp58 PF07902.11 EIM85277.1 - 0.025 12.9 0.1 0.048 12.0 0.1 1.4 1 0 0 1 1 1 0 gp58-like protein HTH_6 PF01418.17 EIM85277.1 - 0.05 13.6 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HALZ PF02183.18 EIM85277.1 - 0.054 13.7 1.0 0.19 12.0 0.7 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Mto2_bdg PF12808.7 EIM85277.1 - 0.77 10.1 0.0 0.77 10.1 0.0 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Med8 PF10232.9 EIM85277.1 - 4.6 6.8 7.2 1.1 8.8 2.7 2.1 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 GED PF02212.18 EIM85279.1 - 0.00062 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.20 EIM85279.1 - 0.0063 15.8 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Tyrosinase PF00264.20 EIM85280.1 - 2.1e-47 162.2 3.3 4e-47 161.3 3.3 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EIM85280.1 - 2e-28 99.5 0.2 4.1e-28 98.5 0.2 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain THAP PF05485.12 EIM85280.1 - 0.12 13.3 0.1 0.42 11.6 0.1 1.9 1 0 0 1 1 1 0 THAP domain GTP_CH_N PF12471.8 EIM85281.1 - 1e-63 214.6 0.0 1.4e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal Pyr_redox_3 PF13738.6 EIM85283.1 - 6.5e-20 71.6 0.0 4e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIM85283.1 - 1.2e-18 66.8 0.0 2.9e-13 49.1 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM85283.1 - 1.4e-12 47.5 0.0 2.7e-09 36.7 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM85283.1 - 9e-10 38.2 0.1 1.9e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EIM85283.1 - 4.7e-06 26.7 0.5 0.0008 19.5 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EIM85283.1 - 4.2e-05 22.9 0.6 0.0011 18.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EIM85283.1 - 6.2e-05 23.1 0.0 0.00029 21.0 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EIM85283.1 - 0.00015 22.3 0.2 0.083 13.5 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EIM85283.1 - 0.00054 20.2 0.1 0.052 13.8 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 EIM85283.1 - 0.0046 16.3 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 EIM85283.1 - 0.0048 16.5 0.2 0.12 12.0 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM85283.1 - 0.0068 16.4 0.0 0.043 13.8 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding ApbA PF02558.16 EIM85283.1 - 0.0092 15.6 0.0 0.33 10.6 0.0 2.8 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EIM85283.1 - 0.013 14.2 0.1 0.036 12.8 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EIM85283.1 - 0.015 14.4 0.1 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein SnoaL_2 PF12680.7 EIM85283.1 - 0.037 14.7 0.0 0.075 13.7 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain 3HCDH_N PF02737.18 EIM85283.1 - 0.041 13.7 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EIM85283.1 - 0.047 12.8 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EIM85283.1 - 0.077 13.4 0.0 3.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EIM85283.1 - 0.15 11.7 0.1 1.9 8.0 0.0 2.6 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 EIM85283.1 - 0.16 11.0 0.1 0.33 10.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain DUF4427 PF14468.6 EIM85284.1 - 0.026 14.6 0.0 21 5.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4427) BTB PF00651.31 EIM85285.1 - 2.5e-05 24.5 0.6 0.00011 22.3 0.6 2.0 1 1 0 1 1 1 1 BTB/POZ domain Extensin-like_C PF06904.12 EIM85285.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Extensin-like protein C-terminus BTB PF00651.31 EIM85286.1 - 9.6e-05 22.6 0.1 0.00028 21.1 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM85287.1 - 1.1e-06 28.9 0.0 2.4e-06 27.7 0.0 1.5 1 1 1 2 2 2 1 BTB/POZ domain Ribos_L4_asso_C PF14374.6 EIM85287.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain BTB PF00651.31 EIM85288.1 - 0.0001 22.5 0.1 0.00033 20.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Apolipoprotein PF01442.18 EIM85289.1 - 0.0039 17.1 3.1 0.011 15.6 1.5 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Csa1 PF06023.12 EIM85289.1 - 0.014 14.8 0.8 0.027 13.8 0.7 1.5 1 1 1 2 2 2 0 CRISPR-associated exonuclease Csa1 Phasin PF05597.11 EIM85289.1 - 0.03 14.3 3.7 0.047 13.7 2.2 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1576 PF07613.11 EIM85289.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) MafB PF06255.13 EIM85289.1 - 0.08 12.4 1.2 0.12 11.8 0.6 1.6 1 1 0 1 1 1 0 Neisseria toxin MafB HisKA_3 PF07730.13 EIM85289.1 - 3.7 8.1 8.3 1 9.9 4.6 1.9 2 0 0 2 2 2 0 Histidine kinase YwpF PF14183.6 EIM85290.1 - 0.088 12.8 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 YwpF-like protein NmrA PF05368.13 EIM85292.1 - 9.5e-16 58.1 0.1 1.3e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EIM85292.1 - 0.0041 17.5 0.0 0.008 16.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PALP PF00291.25 EIM85292.1 - 0.018 14.5 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_10 PF13460.6 EIM85292.1 - 0.074 12.9 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding DUF1501 PF07394.12 EIM85292.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF3602 PF12223.8 EIM85293.1 - 2.6e-20 72.8 37.4 2.6e-07 31.1 6.7 5.5 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) DUF629 PF04780.12 EIM85294.1 - 0.011 14.3 0.1 0.018 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) TAF1D PF15333.6 EIM85294.1 - 0.12 12.1 0.3 0.23 11.2 0.3 1.4 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D CBFD_NFYB_HMF PF00808.23 EIM85295.1 - 7e-20 71.1 1.0 1.1e-19 70.4 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM85295.1 - 1.4e-12 48.1 1.0 6e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SUIM_assoc PF16619.5 EIM85295.1 - 1.3e-05 25.1 2.5 2.8e-05 24.1 2.5 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF1631 PF07793.11 EIM85295.1 - 0.014 13.9 3.9 0.017 13.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CENP-X PF09415.10 EIM85295.1 - 0.067 13.5 1.6 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 CENP-S associating Centromere protein X TAF PF02969.17 EIM85295.1 - 0.19 11.9 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Spt20 PF12090.8 EIM85295.1 - 0.25 10.9 13.1 0.34 10.5 13.1 1.2 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 EIM85295.1 - 0.68 9.0 4.3 0.92 8.5 4.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Med15 PF09606.10 EIM85295.1 - 1.7 7.2 22.1 0.063 12.0 16.5 1.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4637 PF15470.6 EIM85295.1 - 2 8.1 4.5 46 3.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Med3 PF11593.8 EIM85295.1 - 2.2 7.4 15.3 3.6 6.7 15.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF5127 PF17168.4 EIM85296.1 - 8.5e-78 261.2 10.8 1.3e-77 260.7 10.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM85296.1 - 1.1e-74 249.8 0.1 2.1e-74 248.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM85296.1 - 6.9e-61 205.5 0.9 1.6e-60 204.3 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM85296.1 - 6.1e-09 35.3 0.3 4e-08 32.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) WD40 PF00400.32 EIM85298.1 - 1.7e-36 123.6 5.9 9.3e-10 39.0 0.1 5.1 5 0 0 5 5 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM85298.1 - 9.7e-14 51.4 0.1 1.9e-07 31.3 0.0 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EIM85298.1 - 4e-09 36.6 0.4 1.2e-08 35.0 0.4 1.8 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EIM85298.1 - 7.3e-06 25.2 0.2 0.44 9.4 0.0 3.9 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM85298.1 - 9.8e-06 25.1 0.0 0.0057 16.0 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain AAA_16 PF13191.6 EIM85298.1 - 0.00012 22.5 0.1 0.00039 20.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Nup160 PF11715.8 EIM85298.1 - 0.0012 17.6 0.1 2 7.0 0.0 3.8 3 1 1 4 4 4 1 Nucleoporin Nup120/160 AAA_22 PF13401.6 EIM85298.1 - 0.0034 17.7 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EIM85298.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 NTPase PIF1 PF05970.14 EIM85298.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.20 EIM85298.1 - 0.085 12.7 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 EIM85298.1 - 0.1 12.3 0.2 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 EIM85298.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EIM85298.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Frtz PF11768.8 EIM85298.1 - 0.16 10.3 0.0 0.31 9.3 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 EIM85298.1 - 0.25 10.1 0.2 7.3 5.2 0.1 2.9 2 1 1 3 3 3 0 Nup133 N terminal like MFS_1 PF07690.16 EIM85299.1 - 3.1e-42 144.8 54.5 1.7e-32 112.8 15.2 3.3 1 1 3 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 EIM85299.1 - 4.8e-09 35.2 7.8 4.8e-09 35.2 7.8 2.2 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.6 EIM85299.1 - 6.3 6.4 22.0 3.5 7.2 1.8 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) DUF5592 PF17332.2 EIM85299.1 - 9.7 6.8 7.0 29 5.3 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5592) DnaJ PF00226.31 EIM85300.1 - 1.7e-20 72.9 0.3 1.7e-20 72.9 0.3 2.2 3 0 0 3 3 2 1 DnaJ domain TPR_2 PF07719.17 EIM85300.1 - 1.9e-16 58.8 10.6 0.00042 20.2 0.0 7.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EIM85300.1 - 1.6e-15 56.2 0.6 0.00023 20.8 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM85300.1 - 2.7e-14 52.6 0.5 3.6e-09 36.2 0.1 4.4 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 EIM85300.1 - 9.7e-14 51.6 15.6 5.4e-07 30.0 0.4 6.3 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 EIM85300.1 - 7e-11 42.1 6.6 4.8e-05 23.4 0.1 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM85300.1 - 4e-10 40.2 21.6 8e-07 29.6 0.8 5.9 3 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIM85300.1 - 1.1e-09 37.7 1.6 0.78 9.9 0.0 6.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM85300.1 - 4.6e-08 33.2 20.0 0.001 19.7 0.1 6.8 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM85300.1 - 8.7e-08 32.3 10.2 0.59 10.9 0.1 6.6 7 0 0 7 7 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM85300.1 - 1.1e-07 32.0 5.8 0.00051 20.2 0.3 4.8 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EIM85300.1 - 2.1e-06 27.5 4.4 0.14 12.5 0.1 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM85300.1 - 7.8e-05 22.9 13.2 0.072 13.4 0.3 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 EIM85300.1 - 0.00012 22.5 11.3 0.019 15.4 0.0 4.1 2 2 1 3 3 3 2 Bacterial transcriptional activator domain MIT PF04212.18 EIM85300.1 - 0.00013 21.9 2.9 0.51 10.4 0.0 4.8 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EIM85300.1 - 0.00021 21.4 8.0 0.0082 16.5 0.4 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EIM85300.1 - 0.0008 19.8 16.0 0.2 12.3 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 EIM85300.1 - 0.0011 17.7 0.8 0.041 12.6 0.0 2.8 2 1 0 3 3 3 1 Protein of unknown function (DUF3808) SRP_TPR_like PF17004.5 EIM85300.1 - 0.0012 18.9 2.8 0.0053 16.8 0.3 3.0 3 0 0 3 3 3 1 Putative TPR-like repeat PknG_TPR PF16918.5 EIM85300.1 - 0.014 14.1 6.3 0.85 8.3 0.0 3.6 2 1 2 4 4 4 0 Protein kinase G tetratricopeptide repeat DUF4276 PF14103.6 EIM85300.1 - 0.058 13.6 1.1 0.25 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4276) DUF2063 PF09836.9 EIM85300.1 - 0.095 13.0 0.1 0.88 9.9 0.0 2.7 3 0 0 3 3 2 0 Putative DNA-binding domain TPR_10 PF13374.6 EIM85300.1 - 0.11 12.4 6.1 5.3 7.1 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4363 PF14276.6 EIM85300.1 - 0.12 12.5 0.7 1.3 9.2 0.2 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) TPR_21 PF09976.9 EIM85300.1 - 0.36 10.5 18.4 2.2 7.9 7.9 4.3 2 2 3 5 5 5 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EIM85300.1 - 7.3 7.0 14.3 8.6 6.8 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_3_C PF01915.22 EIM85301.1 - 2.5e-50 171.3 0.0 4.2e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM85301.1 - 8.5e-49 166.6 0.0 1.2e-48 166.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM85301.1 - 1.1e-22 79.9 2.1 4.1e-22 78.1 2.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 EIM85301.1 - 0.48 10.7 4.6 0.4 11.0 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF11 Glyco_hydro_92 PF07971.12 EIM85302.1 - 1.8e-145 485.5 2.8 2.2e-145 485.1 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EIM85302.1 - 1.9e-61 208.0 4.7 3.2e-61 207.3 4.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain hnRNP_Q_AcD PF18360.1 EIM85303.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain TIP49 PF06068.13 EIM85305.1 - 1.3e-157 524.6 0.0 1.5e-157 524.3 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EIM85305.1 - 3.5e-19 68.7 0.0 7.1e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EIM85305.1 - 7.1e-10 39.4 0.1 2.3e-06 28.1 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EIM85305.1 - 1.7e-08 34.4 0.0 8.6e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIM85305.1 - 6.2e-07 29.8 0.1 0.014 15.6 0.1 2.4 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIM85305.1 - 7e-06 26.5 0.0 5e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EIM85305.1 - 9.9e-06 25.6 0.1 0.0054 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EIM85305.1 - 0.0013 19.0 0.1 0.0031 17.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EIM85305.1 - 0.0018 17.9 0.1 0.0039 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM85305.1 - 0.0022 18.3 0.6 0.018 15.4 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIM85305.1 - 0.013 15.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EIM85305.1 - 0.035 13.5 0.1 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EIM85305.1 - 0.038 13.7 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EIM85305.1 - 0.045 13.5 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EIM85305.1 - 0.068 12.7 0.1 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EIM85305.1 - 0.085 12.1 0.2 0.31 10.3 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EIM85305.1 - 0.096 13.2 0.1 0.5 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EIM85305.1 - 0.13 12.3 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_lid_2 PF17863.1 EIM85305.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain DUF2075 PF09848.9 EIM85305.1 - 0.2 10.8 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EIM85305.1 - 0.54 9.7 2.1 1.3 8.4 0.1 2.4 3 0 0 3 3 3 0 PhoH-like protein Glyco_hydro_61 PF03443.14 EIM85306.1 - 1.9e-67 227.2 0.1 2.2e-67 227.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ArenaCapSnatch PF17296.2 EIM85306.1 - 0.27 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain Epimerase PF01370.21 EIM85307.1 - 1.4e-18 67.3 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM85307.1 - 4.6e-14 52.1 0.0 1.1e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM85307.1 - 8.4e-12 45.1 0.4 8.6e-11 41.8 0.3 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM85307.1 - 3.4e-09 36.2 0.0 5.3e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EIM85307.1 - 5.1e-09 36.3 0.1 1.5e-08 34.7 0.0 1.8 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EIM85307.1 - 2.4e-05 24.0 0.1 3.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EIM85307.1 - 0.0041 16.6 0.1 0.0091 15.5 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_1 PF00561.20 EIM85309.1 - 1.5e-19 70.7 0.9 1.4e-18 67.5 0.9 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM85309.1 - 5.5e-15 56.6 0.9 8.2e-15 56.0 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM85309.1 - 8.4e-06 25.2 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 EIM85309.1 - 0.013 15.8 0.3 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Ndr PF03096.14 EIM85309.1 - 0.24 10.1 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family PNP_UDP_1 PF01048.20 EIM85313.1 - 3.2e-35 121.5 0.0 3.9e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily FUSC PF04632.12 EIM85314.1 - 0.0024 16.5 13.1 0.0024 16.5 13.1 3.5 1 1 3 4 4 4 1 Fusaric acid resistance protein family HALZ PF02183.18 EIM85314.1 - 0.043 14.0 0.4 0.043 14.0 0.4 11.9 9 5 5 15 15 15 0 Homeobox associated leucine zipper YabA PF06156.13 EIM85314.1 - 0.5 11.0 66.8 3.4 8.4 1.5 9.6 1 1 6 7 7 7 0 Initiation control protein YabA KASH_CCD PF14662.6 EIM85314.1 - 0.58 10.0 81.3 0.7 9.7 15.7 6.3 1 1 5 7 7 7 0 Coiled-coil region of CCDC155 or KASH SH3_1 PF00018.28 EIM85317.1 - 4.6e-05 22.9 0.0 9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM85317.1 - 9e-05 22.3 0.1 9e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EIM85317.1 - 0.0013 18.3 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 EIM85317.1 - 0.84 9.6 19.9 4.3 7.2 19.9 2.0 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Patatin PF01734.22 EIM85318.1 - 1.2e-15 58.3 0.0 3.1e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 EIM85318.1 - 6.4e-07 28.8 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EIM85318.1 - 1.1e-05 25.9 0.1 0.00012 22.5 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM85318.1 - 0.00047 20.4 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EIM85318.1 - 0.0061 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EIM85318.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 EIM85318.1 - 0.018 14.4 0.0 0.054 12.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein HMG_box_5 PF14887.6 EIM85318.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Glyco_hydro_28 PF00295.17 EIM85320.1 - 5.3e-25 88.2 0.7 7.6e-25 87.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EIM85320.1 - 0.00091 19.1 7.7 0.001 19.0 0.8 2.8 1 1 0 2 2 2 1 Pectate lyase superfamily protein ABC_tran PF00005.27 EIM85321.1 - 4.4e-31 108.2 0.2 3.4e-28 98.9 0.0 3.2 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.23 EIM85321.1 - 2.6e-22 79.8 5.0 2e-13 50.6 0.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EIM85321.1 - 0.0002 20.8 0.0 0.014 14.9 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EIM85321.1 - 0.001 19.2 0.5 0.0039 17.3 0.1 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 EIM85321.1 - 0.0034 17.2 1.0 0.65 9.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM85321.1 - 0.066 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3123 PF11321.8 EIM85321.1 - 0.067 13.9 0.5 0.15 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) T2SSE PF00437.20 EIM85321.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4281 PF14108.6 EIM85322.1 - 0.012 15.9 0.9 0.016 15.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) YabA PF06156.13 EIM85324.1 - 0.11 13.2 0.1 0.11 13.2 0.1 4.2 4 0 0 4 4 4 0 Initiation control protein YabA PEARLI-4 PF05278.12 EIM85324.1 - 1 8.9 4.9 0.4 10.2 1.5 2.0 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Pkinase_fungal PF17667.1 EIM85325.1 - 9.6e-84 281.5 0.5 2e-83 280.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EIM85325.1 - 2.4e-09 37.0 0.0 5.5e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85325.1 - 0.0029 16.9 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase JAKMIP_CC3 PF16034.5 EIM85326.1 - 0.00072 19.6 2.2 0.00086 19.3 2.2 1.2 1 0 0 1 1 1 1 JAKMIP CC3 domain Nup54 PF13874.6 EIM85326.1 - 0.0016 18.5 0.9 0.0021 18.2 0.5 1.5 2 0 0 2 2 1 1 Nucleoporin complex subunit 54 Leu_zip PF15294.6 EIM85326.1 - 0.0044 16.6 1.7 0.0047 16.5 1.7 1.1 1 0 0 1 1 1 1 Leucine zipper PV-1 PF06637.11 EIM85326.1 - 0.0091 14.9 1.1 0.0092 14.8 1.1 1.1 1 0 0 1 1 1 1 PV-1 protein (PLVAP) ERM PF00769.19 EIM85326.1 - 0.0096 15.8 4.8 0.011 15.5 4.8 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family BCAS2 PF05700.11 EIM85326.1 - 0.01 15.6 0.7 0.013 15.2 0.7 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) GAS PF13851.6 EIM85326.1 - 0.015 14.7 2.1 0.021 14.2 2.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin_2 PF14523.6 EIM85326.1 - 0.023 15.1 0.1 0.036 14.4 0.1 1.3 1 0 0 1 1 1 0 Syntaxin-like protein bZIP_1 PF00170.21 EIM85326.1 - 0.026 14.6 3.2 0.049 13.7 1.4 2.3 2 1 0 2 2 2 0 bZIP transcription factor RNase_E_G PF10150.9 EIM85326.1 - 0.04 13.3 0.8 0.045 13.2 0.8 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family APG6_N PF17675.1 EIM85326.1 - 0.044 14.3 9.4 0.027 15.0 7.5 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 EIM85326.1 - 0.057 13.7 1.7 3.6 7.9 0.3 2.6 1 1 2 3 3 3 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 EIM85326.1 - 0.11 12.3 5.3 0.19 11.5 4.6 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 EIM85326.1 - 0.16 12.1 2.0 0.2 11.8 2.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_2 PF07716.15 EIM85326.1 - 0.21 11.7 7.4 0.16 12.1 1.4 2.7 3 0 0 3 3 3 0 Basic region leucine zipper DivIC PF04977.15 EIM85326.1 - 0.23 11.2 5.7 0.1 12.4 3.3 1.6 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 EIM85326.1 - 0.33 11.6 2.4 5.6 7.7 0.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 EIM85326.1 - 0.37 11.2 4.9 0.64 10.4 4.7 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) NRBF2 PF08961.10 EIM85326.1 - 0.71 9.5 9.6 0.93 9.1 1.9 2.3 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator FUSC PF04632.12 EIM85326.1 - 0.71 8.3 3.5 0.88 8.0 3.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 EIM85326.1 - 1.5 9.3 8.2 13 6.3 7.2 2.7 1 1 1 2 2 2 0 Cell division protein ZapB PikAIV_N PF18605.1 EIM85326.1 - 4.8 6.8 9.2 9.8 5.9 1.1 3.1 2 1 1 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain QWRF PF04484.12 EIM85327.1 - 0.03 14.1 2.6 0.037 13.8 2.6 1.1 1 0 0 1 1 1 0 QWRF family Epimerase PF01370.21 EIM85328.1 - 6.6e-17 61.8 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM85328.1 - 8.7e-11 41.8 0.1 3.6e-10 39.8 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM85328.1 - 1.2e-10 41.0 0.0 3.8e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EIM85328.1 - 2.7e-07 29.9 0.0 6e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EIM85328.1 - 0.00087 18.5 0.0 0.0081 15.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EIM85328.1 - 0.0093 15.9 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM85328.1 - 0.077 12.9 0.0 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 KR domain Phage_int_SAM_6 PF18644.1 EIM85329.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain F-box PF00646.33 EIM85329.1 - 0.094 12.6 0.3 0.3 11.0 0.3 1.9 1 0 0 1 1 1 0 F-box domain DUF3328 PF11807.8 EIM85330.1 - 6.1e-07 29.5 1.7 3e-06 27.2 1.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SNO PF01174.19 EIM85331.1 - 8e-52 175.8 0.0 2e-41 141.9 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EIM85331.1 - 1.8e-08 34.2 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EIM85331.1 - 0.00064 19.4 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EIM85331.1 - 0.0016 18.3 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Anthrax_toxA PF03497.16 EIM85331.1 - 0.21 11.7 0.0 4.2 7.5 0.0 2.0 2 0 0 2 2 2 0 Anthrax toxin LF subunit DNA_pol_phi PF04931.13 EIM85332.1 - 0.14 10.2 1.2 0.3 9.1 1.2 1.5 1 0 0 1 1 1 0 DNA polymerase phi Pex14_N PF04695.13 EIM85332.1 - 4.4 7.9 10.3 4.2 8.0 5.4 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Putative_PNPOx PF01243.20 EIM85333.1 - 0.00041 20.5 0.0 0.32 11.2 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase COesterase PF00135.28 EIM85334.1 - 6.6e-83 279.3 0.0 7.9e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM85334.1 - 1.1e-05 25.5 0.5 0.096 12.5 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM85334.1 - 0.15 10.9 0.0 0.3 9.9 0.0 1.4 2 0 0 2 2 2 0 Steryl acetyl hydrolase RFC1 PF08519.12 EIM85335.1 - 1.2e-55 188.0 0.0 1.1e-54 184.8 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EIM85335.1 - 1.3e-14 54.4 0.0 3.7e-14 52.9 0.0 1.9 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EIM85335.1 - 6.4e-11 42.8 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EIM85335.1 - 3.5e-07 30.3 0.0 7.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EIM85335.1 - 0.0004 20.4 0.0 0.01 15.8 0.0 2.4 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIM85335.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EIM85335.1 - 0.016 15.6 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EIM85335.1 - 0.02 14.6 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EIM85335.1 - 0.023 14.8 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EIM85335.1 - 0.048 13.9 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 EIM85335.1 - 0.049 14.0 0.0 0.99 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA C-terminal domain AAA_18 PF13238.6 EIM85335.1 - 0.078 13.5 1.1 0.19 12.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain DNA_binding_1 PF01035.20 EIM85336.1 - 1.1e-22 79.9 0.0 1.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain AAA PF00004.29 EIM85339.1 - 7.1e-46 155.9 0.0 1.1e-40 139.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM85339.1 - 4.6e-10 39.1 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIM85339.1 - 2.6e-07 31.2 0.1 3.9e-05 24.1 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 EIM85339.1 - 8.3e-06 25.6 0.0 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EIM85339.1 - 0.00024 21.3 0.0 0.00058 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EIM85339.1 - 0.00094 19.2 0.0 0.0039 17.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM85339.1 - 0.0064 16.8 0.4 0.26 11.6 0.0 3.1 2 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EIM85339.1 - 0.016 15.8 0.9 0.12 12.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EIM85339.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 EIM85339.1 - 0.036 14.2 0.0 0.036 14.2 0.0 2.3 3 0 0 3 3 1 0 AAA domain RuvB_N PF05496.12 EIM85339.1 - 0.046 13.5 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EIM85339.1 - 0.049 13.9 3.4 0.063 13.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EIM85339.1 - 0.073 12.6 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EIM85339.1 - 0.077 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EIM85339.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 EIM85339.1 - 0.11 12.2 0.0 2.3 7.9 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.16 EIM85339.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 EIM85339.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain TMF_DNA_bd PF12329.8 EIM85340.1 - 0.05 13.6 7.7 0.13 12.3 7.7 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AroM PF07302.11 EIM85340.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 AroM protein Spc42p PF11544.8 EIM85340.1 - 0.26 11.3 2.6 0.78 9.8 2.6 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p GST_C_2 PF13410.6 EIM85341.1 - 2.6e-09 37.0 0.0 5.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIM85341.1 - 4.3e-09 36.6 0.0 6.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM85341.1 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM85341.1 - 2.6e-07 30.9 0.0 5.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM85341.1 - 3.5e-05 24.0 0.0 6.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM85341.1 - 6.2e-05 23.1 0.0 0.00014 22.0 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EIM85341.1 - 0.0053 16.6 0.0 0.0095 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_6 PF17171.4 EIM85341.1 - 0.032 14.0 0.0 0.48 10.2 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain YqcI_YcgG PF08892.11 EIM85342.1 - 9.5e-62 208.6 0.0 1.1e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 YqcI/YcgG family Catalase PF00199.19 EIM85343.1 - 6.6e-160 532.4 0.2 8.6e-160 532.0 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EIM85343.1 - 8e-12 45.2 0.0 2.1e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF2204 PF09970.9 EIM85344.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Ribonuc_L-PSP PF01042.21 EIM85346.1 - 4.6e-32 110.6 0.0 5.1e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP F-box-like PF12937.7 EIM85347.1 - 0.015 15.1 0.7 0.034 14.1 0.7 1.6 1 0 0 1 1 1 0 F-box-like Peptidase_S10 PF00450.22 EIM85349.1 - 3.9e-75 253.9 0.0 4.9e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_1 PF00076.22 EIM85351.1 - 1.6e-30 104.7 0.3 3e-14 52.6 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM85351.1 - 5.5e-11 42.5 0.2 2.6e-05 24.2 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EIM85351.1 - 7.9e-05 22.6 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EIM85351.1 - 0.039 14.0 0.0 8.4 6.5 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Suf PF05843.14 EIM85352.1 - 5.3e-58 197.3 3.5 1.7e-56 192.4 0.0 3.1 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EIM85352.1 - 5.8e-11 42.3 0.1 0.42 11.6 0.0 7.1 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM85352.1 - 2.6e-08 34.3 0.1 0.018 15.5 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIM85352.1 - 6.9e-06 25.5 0.4 0.017 14.3 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM85352.1 - 0.0055 16.7 0.0 8 6.8 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIM85352.1 - 0.011 16.3 0.2 21 6.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM85352.1 - 0.032 14.4 0.0 1.4 9.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat FTCD_C PF04961.12 EIM85352.1 - 0.033 14.0 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase AGOG PF09171.10 EIM85352.1 - 0.041 13.2 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Glyco_hydro_85 PF03644.13 EIM85353.1 - 4.6e-81 272.5 0.0 6.2e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 AA_permease PF00324.21 EIM85354.1 - 1.4e-118 396.5 39.6 1.7e-118 396.2 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM85354.1 - 4.8e-29 101.5 38.5 7.3e-29 100.8 38.5 1.2 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 EIM85354.1 - 0.1 12.3 0.1 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Non-classical export protein 1 OPT PF03169.15 EIM85355.1 - 7.9e-117 391.4 51.0 9.1e-117 391.2 51.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 EIM85356.1 - 3.2e-16 59.2 17.1 1.4e-15 57.1 16.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EIM85356.1 - 2.8e-14 53.2 0.8 2.8e-14 53.2 0.8 2.1 2 0 0 2 2 2 1 Nodulin-like LapA_dom PF06305.11 EIM85356.1 - 7.2 6.5 5.5 64 3.5 0.2 3.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain p31comet PF06581.12 EIM85358.1 - 0.00037 19.8 0.0 0.00062 19.0 0.0 1.3 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding Peptidase_S10 PF00450.22 EIM85359.1 - 3.3e-76 257.4 0.0 5.6e-76 256.6 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase HD PF01966.22 EIM85360.1 - 2.9e-10 40.4 0.0 8.2e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 HD domain PDEase_I PF00233.19 EIM85360.1 - 0.00096 18.9 0.2 0.002 17.9 0.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EIM85361.1 - 1.1e-10 41.8 1.1 2e-10 40.9 0.3 1.9 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 EIM85361.1 - 0.039 13.7 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Tcf25 PF04910.14 EIM85364.1 - 2.6e-95 319.5 0.0 3.6e-95 319.0 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_14 PF13428.6 EIM85364.1 - 0.028 15.2 1.1 0.52 11.3 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat CSRNP_N PF16019.5 EIM85364.1 - 0.41 10.5 2.6 0.88 9.4 2.6 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RR_TM4-6 PF06459.12 EIM85364.1 - 5.5 6.7 20.8 4.1 7.1 10.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FGE-sulfatase PF03781.16 EIM85365.1 - 4.4e-21 75.6 4.6 2.3e-11 43.8 0.4 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EIM85365.1 - 5e-08 33.5 0.9 8.9e-08 32.7 0.9 1.4 1 0 0 1 1 1 1 DinB superfamily His_Phos_2 PF00328.22 EIM85366.1 - 3.6e-33 115.5 0.0 4.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 EIM85367.1 - 4e-36 124.7 47.7 2.9e-35 121.9 47.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85367.1 - 6.9e-10 38.4 7.6 6.9e-10 38.4 7.6 3.2 4 0 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 EIM85367.1 - 9.4e-06 24.3 10.9 1.7e-05 23.4 10.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EIM85367.1 - 0.04 12.2 0.1 0.04 12.2 0.1 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family NmrA PF05368.13 EIM85368.1 - 4e-18 65.8 0.0 5.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM85368.1 - 2.6e-17 63.3 0.0 3.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM85368.1 - 4.1e-05 23.2 0.0 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM85368.1 - 0.00082 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EIM85368.1 - 0.049 13.9 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EIM85368.1 - 0.056 12.6 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 EIM85368.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.8 2 1 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 EIM85368.1 - 0.12 11.5 0.0 0.52 9.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein OTCace_N PF02729.21 EIM85368.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain FAD_syn PF06574.12 EIM85368.1 - 0.2 11.5 0.0 1.7 8.5 0.0 2.2 2 1 0 2 2 2 0 FAD synthetase Npa1 PF11707.8 EIM85369.1 - 1.9e-104 349.7 0.2 5.8e-101 338.2 0.0 3.7 3 1 0 3 3 3 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EIM85369.1 - 5.7e-45 153.4 0.3 5.7e-45 153.4 0.3 2.4 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 EIM85369.1 - 0.027 15.2 0.0 0.27 12.0 0.0 2.8 3 0 0 3 3 3 0 Creb binding DNA_pol_phi PF04931.13 EIM85369.1 - 0.041 12.0 0.0 0.12 10.5 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase phi CMD PF02627.20 EIM85370.1 - 6.2e-19 67.8 0.1 1.5e-18 66.6 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family NAD_binding_2 PF03446.15 EIM85371.1 - 3.5e-34 118.3 0.0 4.7e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EIM85371.1 - 3.4e-21 75.7 0.0 5.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Peptidase_A25 PF03418.14 EIM85371.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Germination protease MFS_1 PF07690.16 EIM85372.1 - 2.5e-18 66.1 35.6 4.9e-18 65.2 26.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 EIM85372.1 - 0.0001 21.7 1.1 0.0001 21.7 1.1 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PRCH PF03967.13 EIM85372.1 - 0.00014 22.1 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 Photosynthetic reaction centre, H-chain N-terminal region DUF2070 PF09843.9 EIM85372.1 - 0.012 13.9 2.7 0.02 13.2 2.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ADH_N PF08240.12 EIM85373.1 - 5.7e-23 80.9 0.6 9.1e-23 80.2 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM85373.1 - 4e-15 55.9 0.0 8.8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EIM85373.1 - 0.0032 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EIM85373.1 - 0.086 13.9 0.0 0.19 12.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PADR1 PF08063.12 EIM85373.1 - 0.42 10.4 4.7 0.85 9.5 4.7 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain DIOX_N PF14226.6 EIM85374.1 - 5.4e-19 69.1 0.2 3.3e-17 63.3 0.0 2.6 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM85374.1 - 9.7e-12 45.3 0.1 1.8e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIM85375.1 - 4.2e-19 69.4 0.1 6.5e-18 65.6 0.0 2.5 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM85375.1 - 1.4e-11 44.8 0.0 2.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exo_endo_phos PF03372.23 EIM85376.1 - 3.3e-09 36.6 0.0 6.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WW PF00397.26 EIM85377.1 - 0.047 13.8 0.4 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 WW domain CCB1 PF12046.8 EIM85377.1 - 0.061 12.7 1.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Apt1 PF10351.9 EIM85377.1 - 0.17 10.7 3.8 0.22 10.3 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC_export PF16962.5 EIM85377.1 - 0.43 9.0 2.0 0.81 8.1 2.0 1.3 1 0 0 1 1 1 0 Putative ABC exporter SOG2 PF10428.9 EIM85377.1 - 0.83 8.8 10.5 1.2 8.2 10.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EIM85377.1 - 6.9 6.5 15.7 11 5.8 15.7 1.3 1 0 0 1 1 1 0 SPX domain Mannitol_dh_C PF08125.13 EIM85379.1 - 1.2e-44 152.7 0.0 1.1e-39 136.4 0.0 2.2 2 0 0 2 2 2 2 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EIM85379.1 - 2.3e-21 76.6 0.0 3.5e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Retrotrans_gag PF03732.17 EIM85380.1 - 1.9e-14 53.7 0.1 8.1e-14 51.7 0.1 2.0 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIM85380.1 - 7.2e-06 25.8 9.7 0.0032 17.5 2.3 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.6 EIM85380.1 - 0.0042 17.0 2.7 0.01 15.7 2.7 1.6 1 0 0 1 1 1 1 Nudix N-terminal zf-CCHC_5 PF14787.6 EIM85380.1 - 2.1 8.1 6.3 8.5 6.2 0.2 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Mannitol_dh_C PF08125.13 EIM85381.1 - 3.7e-46 157.6 0.0 3.6e-41 141.3 0.0 2.6 3 0 0 3 3 3 2 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EIM85381.1 - 7.8e-22 78.1 0.0 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain RA PF00788.23 EIM85385.1 - 2.9e-12 47.1 0.1 1.2e-10 41.8 0.0 3.3 4 0 0 4 4 4 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 EIM85385.1 - 1.2e-05 24.8 0.2 3.6e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EIM85385.1 - 0.0052 16.6 0.1 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Par3_HAL_N_term PF12053.8 EIM85385.1 - 0.19 12.0 0.0 0.57 10.4 0.0 1.8 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Vma12 PF11712.8 EIM85385.1 - 9.2 6.3 6.9 4.4 7.4 3.3 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Gly-zipper_Omp PF13488.6 EIM85387.1 - 0.0072 16.3 0.6 0.016 15.2 0.6 1.5 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EIM85387.1 - 0.019 14.7 0.2 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper SKG6 PF08693.10 EIM85387.1 - 0.088 12.2 1.0 0.18 11.2 0.2 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Amnionless PF14828.6 EIM85387.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Gram_pos_anchor PF00746.21 EIM85387.1 - 1.4 9.0 3.2 3.4 7.7 3.2 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Actin PF00022.19 EIM85388.1 - 1.1e-89 300.9 0.0 2.6e-88 296.4 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EIM85388.1 - 0.00088 18.2 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 EIM85388.1 - 0.025 15.0 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsA Rsa3 PF14615.6 EIM85389.1 - 1.8e-17 62.6 0.0 2.4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 NPR3 PF03666.13 EIM85389.1 - 0.018 13.9 1.3 0.018 13.8 1.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIF_alpha PF05793.12 EIM85389.1 - 0.12 10.9 9.7 0.19 10.3 9.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 EIM85389.1 - 0.17 10.7 6.1 0.17 10.7 6.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NST1 PF13945.6 EIM85389.1 - 4.7 7.3 11.7 14 5.7 8.9 2.0 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF4551 PF15087.6 EIM85389.1 - 7.5 5.3 5.8 7.3 5.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ldh_1_C PF02866.18 EIM85391.1 - 1.3e-44 152.1 0.0 2.6e-44 151.1 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EIM85391.1 - 1.7e-43 148.1 0.1 2.3e-43 147.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EIM85391.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EIM85391.1 - 0.059 13.8 0.5 0.13 12.7 0.1 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 EIM85391.1 - 0.18 11.3 0.2 1.8 8.1 0.1 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase DUF1768 PF08719.11 EIM85392.1 - 4.6e-28 98.5 0.1 7e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1202 PF06717.11 EIM85392.1 - 0.02 14.3 0.1 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Metallothio_Pro PF02069.16 EIM85392.1 - 0.037 14.2 10.2 2.8 8.2 0.6 3.5 3 0 0 3 3 3 0 Prokaryotic metallothionein zf-FCS PF06467.14 EIM85392.1 - 0.098 12.6 0.5 0.098 12.6 0.5 4.1 3 2 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-MYND PF01753.18 EIM85392.1 - 0.62 10.2 19.3 0.86 9.7 2.1 3.8 3 0 0 3 3 3 0 MYND finger RPAP2_Rtr1 PF04181.13 EIM85392.1 - 1.1 9.6 10.6 2.1 8.7 0.7 3.4 3 0 0 3 3 3 0 Rtr1/RPAP2 family YacG PF03884.14 EIM85392.1 - 2.6 7.8 20.9 4 7.3 1.5 3.6 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-HIT PF04438.16 EIM85392.1 - 3.8 7.5 26.4 1.3 9.0 0.3 4.4 3 2 0 3 3 3 0 HIT zinc finger PARP PF00644.20 EIM85393.1 - 7e-16 58.4 1.4 1.6e-10 40.9 0.0 3.0 2 1 1 3 3 3 3 Poly(ADP-ribose) polymerase catalytic domain PhyH PF05721.13 EIM85394.1 - 7e-22 78.7 0.8 1.6e-21 77.6 0.8 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.11 EIM85394.1 - 0.039 13.7 0.1 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Cyclin_N PF00134.23 EIM85395.1 - 6.3e-11 42.1 0.0 2.7e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EIM85395.1 - 0.0098 16.3 0.1 0.028 14.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 EIM85395.1 - 0.022 14.8 0.2 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.19 EIM85395.1 - 0.18 11.9 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat ZapB PF06005.12 EIM85396.1 - 0.01 16.3 7.7 0.02 15.3 7.7 1.5 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 EIM85396.1 - 0.11 13.2 0.4 0.19 12.4 0.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Uso1_p115_C PF04871.13 EIM85396.1 - 0.14 12.6 2.8 0.23 11.8 2.8 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 EIM85396.1 - 0.47 10.2 3.9 0.92 9.3 3.9 1.4 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.8 EIM85396.1 - 2.7 8.1 6.9 4.4 7.4 6.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 EIM85396.1 - 3.1 7.0 7.9 0.64 9.3 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Actin PF00022.19 EIM85397.1 - 6.8e-148 492.6 0.0 5.5e-147 489.6 0.0 1.9 1 1 0 1 1 1 1 Actin GerD PF17898.1 EIM85397.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 Spore germination GerD central core domain Cpn60_TCP1 PF00118.24 EIM85399.1 - 8.4e-146 486.4 13.1 9.6e-146 486.2 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EIM85399.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat zf-C2H2_4 PF13894.6 EIM85400.1 - 0.066 14.1 0.4 0.066 14.1 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger RestrictionMunI PF11407.8 EIM85400.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI DUF4106 PF13388.6 EIM85400.1 - 1 8.5 6.9 0.42 9.8 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) zf-C2H2 PF00096.26 EIM85400.1 - 3.1 8.4 16.0 0.56 10.8 4.5 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type IBR PF01485.21 EIM85400.1 - 5.5 7.3 7.6 1.6 9.0 0.4 3.1 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain PMT PF02366.18 EIM85401.1 - 5.4e-76 255.4 14.6 1.3e-75 254.2 14.6 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EIM85401.1 - 2.1e-66 223.4 14.4 2.1e-66 223.4 14.4 2.1 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EIM85401.1 - 4e-37 127.9 0.1 8.2e-37 126.8 0.0 1.6 2 0 0 2 2 2 1 MIR domain Focadhesin PF11229.8 EIM85402.1 - 0.04 12.2 3.2 0.054 11.7 3.2 1.1 1 0 0 1 1 1 0 Focadhesin Retrotrans_gag PF03732.17 EIM85404.1 - 4.3e-08 33.3 0.0 8.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 EIM85404.1 - 1.4e-06 28.1 0.0 3.1e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) MFS_1 PF07690.16 EIM85405.1 - 4.1e-12 45.7 33.0 7.6e-12 44.8 33.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EIM85405.1 - 0.00031 20.5 5.6 0.00031 20.5 5.6 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Actin PF00022.19 EIM85406.1 - 6.2e-147 489.5 0.0 3.7e-146 486.9 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 EIM85406.1 - 0.13 10.8 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-C2H2 PF00096.26 EIM85407.1 - 6e-05 23.3 10.9 0.064 13.7 0.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM85407.1 - 0.093 13.6 10.3 0.58 11.2 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EIM85408.1 - 1.9e-06 28.0 12.5 0.23 12.0 4.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM85408.1 - 0.00086 19.9 13.1 2.3 9.3 0.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM85408.1 - 0.027 14.9 11.5 0.082 13.4 1.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 EIM85408.1 - 0.042 13.6 0.0 0.042 13.6 0.0 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EIM85408.1 - 0.043 13.6 0.9 0.043 13.6 0.9 3.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain VWA_2 PF13519.6 EIM85409.1 - 1.8e-22 80.0 0.1 1e-21 77.6 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EIM85409.1 - 3.3e-09 37.3 0.0 4e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EIM85409.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like F-box PF00646.33 EIM85411.1 - 0.17 11.8 4.4 0.47 10.4 1.2 3.0 2 1 0 2 2 2 0 F-box domain EMG1 PF03587.14 EIM85412.1 - 2.6e-77 258.9 0.0 3.3e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UPRTase PF14681.6 EIM85413.1 - 2.1e-76 256.0 0.0 2.8e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EIM85413.1 - 0.00057 19.4 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SCO1-SenC PF02630.14 EIM85414.1 - 7.9e-47 158.5 0.0 1.1e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EIM85414.1 - 8.4e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EIM85414.1 - 0.00031 21.0 0.0 0.00048 20.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like FAM165 PF14981.6 EIM85414.1 - 0.18 11.6 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 FAM165 family NDUF_B7 PF05676.13 EIM85415.1 - 2.9e-31 107.0 2.0 3.6e-31 106.7 2.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EIM85415.1 - 0.0008 19.4 1.6 0.0014 18.6 1.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Cauli_VI PF01693.16 EIM85417.1 - 0.00092 19.5 0.3 0.0025 18.1 0.1 1.8 2 0 0 2 2 2 1 Caulimovirus viroplasmin KDZ PF18758.1 EIM85420.1 - 1.2e-60 205.0 0.0 2e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM85420.1 - 5.2e-34 116.6 0.0 1.5e-33 115.2 0.0 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM85420.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 EIM85420.1 - 5.9 7.1 9.4 0.28 11.4 3.4 2.0 2 0 0 2 2 2 0 B-box zinc finger Peptidase_C48 PF02902.19 EIM85422.1 - 0.0023 17.8 1.2 0.0023 17.8 1.2 2.2 2 2 1 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Asp-B-Hydro_N PF05279.11 EIM85422.1 - 2.1 8.3 19.3 3.2 7.8 19.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_M23_N PF18421.1 EIM85423.1 - 0.03 14.2 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain DDE_3 PF13358.6 EIM85423.1 - 0.15 11.8 0.0 5.4 6.8 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease Helicase_C PF00271.31 EIM85430.1 - 3.3e-08 33.9 0.0 1.7e-07 31.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM85430.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Retrotran_gag_2 PF14223.6 EIM85431.1 - 1.1e-09 38.1 0.1 1.4e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EIM85431.1 - 0.00018 21.2 0.1 0.00046 19.9 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type F-box-like PF12937.7 EIM85432.1 - 4.8e-06 26.4 0.2 4.1e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM85432.1 - 0.013 15.4 0.1 0.013 15.4 0.1 2.8 3 0 0 3 3 3 0 F-box domain LRR_1 PF00560.33 EIM85432.1 - 3.5 8.5 6.4 26 5.9 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat RXT2_N PF08595.11 EIM85434.1 - 8.7 6.4 10.8 0.41 10.7 4.3 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF5528 PF17666.1 EIM85436.1 - 0.48 10.4 1.8 0.53 10.2 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5528) Suf PF05843.14 EIM85436.1 - 4.2 7.3 5.7 0.61 10.0 1.6 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AI-2E_transport PF01594.16 EIM85437.1 - 0.27 10.3 0.0 0.36 9.9 0.0 1.1 1 0 0 1 1 1 0 AI-2E family transporter Ndc1_Nup PF09531.10 EIM85438.1 - 0.24 10.0 0.3 0.27 9.9 0.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DEAD PF00270.29 EIM85439.1 - 6.2e-33 114.0 0.0 2.4e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM85439.1 - 2.6e-13 50.3 0.0 1.1e-11 45.1 0.0 2.3 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM85439.1 - 0.046 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Ndufs5 PF10200.9 EIM85439.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DDE_1 PF03184.19 EIM85446.1 - 3e-10 40.1 0.0 7.8e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIM85446.1 - 0.0012 18.7 0.0 0.22 11.3 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DUF3656 PF12392.8 EIM85446.1 - 0.16 12.6 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 Collagenase PMI_typeI PF01238.21 EIM85447.1 - 1.8e-109 366.4 0.0 2.1e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EIM85447.1 - 0.00031 20.4 0.5 0.74 9.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EIM85447.1 - 0.0053 16.7 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain CGI-121 PF08617.10 EIM85448.1 - 1.6e-50 171.4 1.5 1.8e-50 171.2 1.5 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 EIM85449.1 - 2.9e-52 174.9 0.1 1.8e-25 88.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EIM85449.1 - 1.1e-17 64.6 0.0 4.7e-08 33.2 0.0 3.9 2 1 2 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EIM85449.1 - 1.8e-07 30.8 0.1 0.19 11.1 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EIM85449.1 - 7.4e-06 26.2 0.0 0.29 11.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.6 EIM85449.1 - 0.0018 18.3 0.0 0.49 10.5 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.21 EIM85449.1 - 0.0048 16.8 0.1 3.6 7.5 0.1 2.5 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 EIM85449.1 - 0.0055 16.6 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EIM85449.1 - 0.0098 16.3 0.3 5.9 7.4 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EIM85449.1 - 0.014 15.6 0.3 0.77 10.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_4 PF13462.6 EIM85449.1 - 0.071 13.3 0.4 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.6 EIM85449.1 - 0.076 12.8 0.2 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DDE_Tnp_1_2 PF13586.6 EIM85449.1 - 0.21 12.0 0.0 4.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Terminase_GpA PF05876.12 EIM85449.1 - 1.2 7.6 3.0 0.71 8.3 0.2 1.8 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Sec63 PF02889.16 EIM85451.1 - 3.1e-21 75.7 0.0 6.9e-21 74.6 0.0 1.5 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 EIM85451.1 - 4.9e-15 55.4 0.4 2e-14 53.5 0.4 2.2 1 0 0 1 1 1 1 DnaJ domain PPR_2 PF13041.6 EIM85452.1 - 1e-49 166.5 0.2 2.1e-10 40.6 0.1 13.6 13 1 2 15 15 15 7 PPR repeat family PPR_1 PF12854.7 EIM85452.1 - 3.1e-37 126.0 0.0 4.1e-08 32.8 0.0 10.7 11 0 0 11 11 11 6 PPR repeat PPR PF01535.20 EIM85452.1 - 8.6e-35 116.6 8.1 2.2e-06 27.5 0.0 13.8 17 0 0 17 17 16 5 PPR repeat PPR_3 PF13812.6 EIM85452.1 - 3.8e-28 97.4 0.0 1.6e-08 34.5 0.0 9.3 7 2 1 9 9 9 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EIM85452.1 - 3.3e-11 43.0 7.5 1.4e-08 34.3 0.2 6.2 5 2 0 7 7 7 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EIM85452.1 - 1e-06 29.0 10.9 8.8 7.5 0.0 9.9 11 1 1 12 12 11 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM85452.1 - 3.1e-06 27.6 7.1 0.49 10.9 0.0 7.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM85452.1 - 0.001 18.9 0.3 46 4.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat RPM2 PF08579.11 EIM85452.1 - 0.0044 17.4 0.0 0.49 10.8 0.0 3.4 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_8 PF13181.6 EIM85452.1 - 0.061 13.6 1.3 2.5 8.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat EccE PF11203.8 EIM85452.1 - 0.16 12.3 5.1 0.058 13.7 1.2 2.3 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE SH3_1 PF00018.28 EIM85453.1 - 6.5e-12 44.9 0.0 1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM85453.1 - 2.4e-11 43.3 0.0 3.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIM85453.1 - 4.4e-07 29.5 0.0 7.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SOBP PF15279.6 EIM85453.1 - 2.4 8.7 10.5 3.2 8.3 10.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Glyco_hydro_cc PF11790.8 EIM85454.1 - 2.8e-62 210.4 0.6 3.3e-62 210.2 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1996 PF09362.10 EIM85455.1 - 2.7e-75 253.4 0.6 3.5e-75 253.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Amidase PF01425.21 EIM85456.1 - 9.4e-71 239.1 0.0 8.1e-69 232.7 0.0 2.0 1 1 1 2 2 2 2 Amidase Mito_carr PF00153.27 EIM85458.1 - 3.2e-45 152.0 3.1 1.2e-15 57.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein VitK2_biosynth PF02621.14 EIM85458.1 - 3.3e-05 23.5 0.3 4.6e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 Menaquinone biosynthesis Acyl-CoA_dh_1 PF00441.24 EIM85459.1 - 3.7e-43 147.3 1.1 5e-43 146.9 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EIM85459.1 - 4.2e-26 91.8 0.1 2.6e-25 89.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EIM85459.1 - 2.8e-23 81.9 0.1 1.1e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIM85459.1 - 2.1e-19 70.1 0.1 3.3e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EIM85459.1 - 0.039 14.5 0.0 0.093 13.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal S36_mt PF10937.8 EIM85460.1 - 6.6e-09 37.4 1.9 3e-06 28.8 1.9 2.2 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial RNA_pol_Rpb1_1 PF04997.12 EIM85461.1 - 1e-88 297.7 0.0 1.5e-88 297.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EIM85461.1 - 1.5e-82 277.1 0.2 2.4e-82 276.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EIM85461.1 - 6.1e-73 244.5 0.0 1.2e-72 243.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EIM85461.1 - 4.4e-36 124.2 0.0 1.5e-35 122.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EIM85461.1 - 1.4e-31 108.6 0.0 3e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Proteasome PF00227.26 EIM85462.1 - 3.7e-44 150.5 0.3 1.9e-43 148.2 0.3 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIM85462.1 - 1.1e-14 53.7 0.3 2.1e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PC-Esterase PF13839.6 EIM85463.1 - 0.00079 19.2 0.0 0.094 12.4 0.0 2.6 2 2 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p GDI PF00996.18 EIM85464.1 - 8.9e-41 139.8 0.0 6.7e-39 133.6 0.0 2.2 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EIM85464.1 - 6.2e-06 26.3 0.1 0.0017 18.5 0.0 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain G-gamma PF00631.22 EIM85464.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 GGL domain RRM_1 PF00076.22 EIM85465.1 - 2.5e-40 136.1 0.0 1e-18 66.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM85465.1 - 5.5e-05 23.2 0.0 0.33 11.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EIM85465.1 - 0.028 14.4 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.18 EIM85466.1 - 8e-07 29.1 6.8 1.3e-06 28.4 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 EIM85466.1 - 1.1 9.8 7.4 24 5.5 7.4 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Ric8 PF10165.9 EIM85467.1 - 5.9e-111 371.7 0.0 1e-110 370.9 0.0 1.3 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn F-box-like PF12937.7 EIM85468.1 - 9.5e-08 31.8 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2194 PF09960.9 EIM85470.1 - 1e-05 24.2 0.0 0.0095 14.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2194) Methyltransf_24 PF13578.6 EIM85470.1 - 0.0017 19.3 5.0 1.2 10.2 0.1 3.3 3 0 0 3 3 3 2 Methyltransferase domain DUF1120 PF06551.12 EIM85470.1 - 0.038 14.2 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1120) AAA_5 PF07728.14 EIM85470.1 - 0.16 12.0 0.0 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Cyclin PF08613.11 EIM85471.1 - 1.9e-43 148.6 0.1 1.9e-43 148.6 0.1 2.7 1 1 1 2 2 2 1 Cyclin PPP4R2 PF09184.11 EIM85471.1 - 0.004 16.8 6.5 0.004 16.8 6.5 2.2 2 0 0 2 2 2 1 PPP4R2 T3SS_TC PF06511.11 EIM85471.1 - 3.8 6.8 8.7 7.1 5.9 8.7 1.4 1 0 0 1 1 1 0 Type III secretion systems tip complex components Utp14 PF04615.13 EIM85471.1 - 6.9 5.1 9.1 4.1 5.9 1.1 2.1 2 0 0 2 2 2 0 Utp14 protein MFS_1 PF07690.16 EIM85473.1 - 4.1e-20 72.0 39.2 1.4e-14 53.9 12.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M56 PF05569.11 EIM85473.1 - 0.056 12.6 1.4 0.12 11.5 0.2 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 FTR1 PF03239.14 EIM85473.1 - 3.1 6.9 19.5 0.029 13.5 9.0 2.5 3 0 0 3 3 3 0 Iron permease FTR1 family Spt4 PF06093.13 EIM85475.1 - 4.4e-30 103.6 0.1 5.4e-30 103.3 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Lipase_3 PF01764.25 EIM85476.1 - 3.9e-11 43.0 0.0 1.3e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) PIGA PF08288.12 EIM85477.1 - 7.4e-38 129.0 0.2 2e-37 127.7 0.2 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EIM85477.1 - 6.1e-29 101.2 0.8 9.9e-29 100.5 0.8 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EIM85477.1 - 6.2e-23 81.2 0.0 9.6e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIM85477.1 - 4.6e-21 75.7 0.0 9.7e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EIM85477.1 - 4.5e-14 53.2 0.1 7.5e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EIM85477.1 - 0.0046 17.0 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EIM85477.1 - 0.0088 16.4 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2433 PF10360.9 EIM85478.1 - 2.8e-45 153.4 0.1 5.9e-45 152.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 EIM85478.1 - 1.3e-06 28.2 0.1 2.5e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 EIM85478.1 - 0.095 12.3 7.5 0.16 11.6 7.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Metallophos PF00149.28 EIM85478.1 - 0.21 12.1 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF4778 PF16008.5 EIM85478.1 - 0.21 11.6 0.3 0.3 11.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TAF4 PF05236.14 EIM85478.1 - 4.2 7.0 10.8 7.2 6.3 10.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Med13_C PF06333.12 EIM85479.1 - 2.4e-48 165.1 2.9 2.4e-48 165.1 2.9 3.8 3 1 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EIM85479.1 - 2.9e-45 155.0 4.3 2.9e-45 155.0 4.3 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal PRKCSH-like PF12999.7 EIM85482.1 - 6.5e-48 162.8 0.4 1.1e-47 162.1 0.4 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EIM85482.1 - 5.7e-26 91.1 0.3 1.4e-25 89.8 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EIM85482.1 - 3.3e-10 40.8 1.0 3.3e-10 40.8 1.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF4406 PF14359.6 EIM85482.1 - 0.032 14.7 0.1 0.37 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4406) Ldl_recept_a PF00057.18 EIM85482.1 - 0.07 13.4 12.5 0.52 10.6 1.3 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A BLOC1S3 PF15753.5 EIM85482.1 - 0.072 13.2 0.4 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Peptidase_M24 PF00557.24 EIM85484.1 - 4.5e-57 193.1 0.0 6.7e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EIM85484.1 - 1.1e-39 135.0 0.0 2.4e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AA_permease_2 PF13520.6 EIM85485.1 - 3.4e-41 141.5 44.0 4.2e-41 141.2 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM85485.1 - 5.7e-21 74.7 37.5 6.5e-21 74.5 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease SHR3_chaperone PF08229.11 EIM85485.1 - 0.5 9.3 2.6 3 6.8 0.4 2.5 1 1 1 2 2 2 0 ER membrane protein SH3 AGTRAP PF06396.11 EIM85485.1 - 1.2 8.9 7.0 0.48 10.2 3.7 2.1 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) F-box-like PF12937.7 EIM85486.1 - 2.9e-05 23.9 0.4 2.9e-05 23.9 0.4 2.1 2 0 0 2 2 2 1 F-box-like PaaX_C PF08223.11 EIM85486.1 - 0.12 12.7 0.2 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Ribosomal_S25 PF03297.15 EIM85487.1 - 9.8e-40 134.8 0.4 1.1e-39 134.7 0.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 EIM85487.1 - 0.015 14.8 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FGGY_C PF02782.16 EIM85488.1 - 1.3e-43 149.1 0.2 1.8e-43 148.6 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EIM85488.1 - 1.6e-17 63.9 1.8 1.6e-15 57.4 0.0 3.0 2 1 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EIM85488.1 - 3.2e-05 23.6 0.4 0.0032 17.0 0.1 2.5 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family TSNR_N PF04705.12 EIM85488.1 - 0.083 13.0 0.1 7.6 6.7 0.0 2.5 3 0 0 3 3 3 0 Thiostrepton-resistance methylase, N terminus DUF2062 PF09835.9 EIM85488.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Ribosomal_L2_C PF03947.18 EIM85489.1 - 2.3e-45 153.8 3.5 4e-45 153.1 3.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EIM85489.1 - 8.7e-16 57.7 0.1 2.1e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_S9_N PF02897.15 EIM85490.1 - 9.1e-91 304.7 7.5 1.2e-90 304.3 7.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EIM85490.1 - 3.6e-54 183.4 0.0 8.8e-54 182.2 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EIM85490.1 - 0.00043 20.2 0.6 0.0029 17.5 0.6 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mito_carr PF00153.27 EIM85491.1 - 8.3e-64 211.6 0.6 1.1e-21 76.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 EIM85493.1 - 1.6e-28 99.8 0.1 2.5e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIM85493.1 - 8e-18 64.4 0.4 1.8e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EIM85493.1 - 5.9e-17 61.6 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EIM85493.1 - 1.6e-15 57.7 0.0 3.8e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EIM85493.1 - 0.0019 18.5 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain F-box-like PF12937.7 EIM85494.1 - 7.4e-09 35.4 0.2 1.5e-08 34.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM85494.1 - 4.5e-06 26.4 0.3 1.1e-05 25.2 0.3 1.6 1 0 0 1 1 1 1 F-box domain Corona_NS1 PF06145.11 EIM85494.1 - 0.19 11.3 0.4 0.35 10.4 0.4 1.4 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 MIF4G_like PF09088.11 EIM85495.1 - 2.7e-67 226.2 0.1 5.5e-67 225.3 0.0 1.6 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 EIM85495.1 - 3.2e-65 220.3 0.0 4.4e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 MIF4G like UAA PF08449.11 EIM85496.1 - 2.1e-71 240.6 17.8 9e-37 126.9 0.5 4.1 3 1 1 4 4 4 4 UAA transporter family Colicin_V PF02674.16 EIM85496.1 - 0.29 11.1 14.5 2.8 7.9 0.3 3.8 2 1 1 3 3 3 0 Colicin V production protein Cyclin_N PF00134.23 EIM85497.1 - 3.2e-16 59.2 0.0 4.2e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EIM85497.1 - 4e-10 40.3 0.0 4.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin dCMP_cyt_deam_1 PF00383.23 EIM85498.1 - 1.1e-22 79.7 0.1 1.8e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIM85498.1 - 1.2e-22 80.1 0.3 3.4e-22 78.7 0.3 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EIM85498.1 - 8e-05 22.7 1.0 0.0043 17.1 1.0 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EIM85498.1 - 0.0024 18.0 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EIM85498.1 - 0.05 13.7 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 EIM85498.1 - 0.064 13.3 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 EIM85498.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 PPR_2 PF13041.6 EIM85499.1 - 6e-10 39.2 0.0 0.00084 19.5 0.0 4.7 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EIM85499.1 - 3.8e-06 26.9 0.4 0.037 14.1 0.1 5.1 6 1 1 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.20 EIM85499.1 - 0.035 14.3 2.6 27 5.3 0.0 5.6 7 0 0 7 7 7 0 PPR repeat URO-D PF01208.17 EIM85500.1 - 3.1e-130 434.4 0.0 3.4e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SH3_1 PF00018.28 EIM85501.1 - 1.9e-20 72.2 0.0 2e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EIM85501.1 - 9.7e-16 57.4 0.0 9.9e-09 34.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EIM85501.1 - 7.1e-12 44.8 0.0 1.8e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EIM85501.1 - 3e-06 27.2 0.2 7.5e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 EIM85501.1 - 0.017 15.1 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 PB1 domain Retrotrans_gag PF03732.17 EIM85501.1 - 0.071 13.4 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein SOG2 PF10428.9 EIM85501.1 - 0.49 9.5 12.4 2.3 7.3 10.9 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein SPX PF03105.19 EIM85501.1 - 2.7 7.8 11.6 2.4 8.0 8.7 2.2 2 0 0 2 2 2 0 SPX domain Not3 PF04065.15 EIM85502.1 - 7.2e-88 293.9 21.7 1.1e-87 293.3 21.7 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EIM85502.1 - 2.5e-43 147.3 6.9 2.5e-43 147.3 6.9 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 EIM85502.1 - 0.002 18.4 3.2 0.0091 16.4 3.2 2.1 1 0 0 1 1 1 1 Syntaxin-like protein HIP1_clath_bdg PF16515.5 EIM85502.1 - 7 7.3 20.2 2.8 8.6 6.1 3.2 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RVT_1 PF00078.27 EIM85503.1 - 1.5e-07 31.2 0.0 5.6e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRD1_DD PF11087.8 EIM85504.1 - 0.084 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery GTP_EFTU PF00009.27 EIM85505.1 - 1.2e-34 119.6 1.0 2.9e-34 118.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EIM85505.1 - 1.4e-19 70.1 0.0 3.7e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EIM85505.1 - 3.8e-14 52.8 7.2 2.2e-10 40.8 0.2 3.9 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM85505.1 - 6.9e-07 29.3 0.1 8.7e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EIM85505.1 - 7.6e-06 25.7 0.1 3.1e-05 23.8 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 EIM85505.1 - 0.00017 21.8 0.3 0.00062 20.0 0.0 2.1 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase Cwf_Cwc_15 PF04889.12 EIM85505.1 - 0.0072 16.1 18.1 0.0072 16.1 18.1 4.4 3 1 1 4 4 3 1 Cwf15/Cwc15 cell cycle control protein Ras PF00071.22 EIM85505.1 - 0.012 15.3 0.0 0.071 12.7 0.0 2.4 2 1 0 2 2 2 0 Ras family ATP_bind_1 PF03029.17 EIM85505.1 - 0.018 14.8 0.0 0.053 13.3 0.0 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EIM85505.1 - 0.04 14.2 0.1 0.2 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EIM85505.1 - 0.13 12.1 0.5 2 8.3 0.2 2.8 1 1 1 2 2 2 0 RsgA GTPase Arf PF00025.21 EIM85506.1 - 1.8e-68 229.4 0.5 2.1e-68 229.2 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EIM85506.1 - 2.6e-14 53.2 1.5 1.6e-08 34.2 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EIM85506.1 - 5.8e-10 39.4 0.0 1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EIM85506.1 - 1.3e-08 34.5 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIM85506.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EIM85506.1 - 1.7e-07 31.0 0.0 2.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EIM85506.1 - 5.5e-06 26.4 0.0 8.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EIM85506.1 - 0.05 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EIM85506.1 - 0.052 13.6 0.0 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 EIM85506.1 - 0.13 12.8 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMAS PF02353.20 EIM85508.1 - 8.5e-59 199.1 0.0 1.2e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EIM85508.1 - 7.8e-10 39.3 0.0 1.6e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM85508.1 - 7.3e-08 33.0 0.0 1.8e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM85508.1 - 2.2e-07 30.8 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM85508.1 - 6.6e-05 22.7 0.0 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM85508.1 - 0.0012 19.6 0.0 0.0031 18.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 EIM85508.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.6 EIM85508.1 - 0.015 16.3 0.0 0.075 14.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 EIM85508.1 - 0.044 13.5 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EIM85508.1 - 0.056 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FA_desaturase PF00487.24 EIM85509.1 - 2.3e-16 60.4 25.9 4e-16 59.6 25.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIM85509.1 - 5.4e-11 42.5 0.1 9.4e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Lys_export PF03956.13 EIM85509.1 - 0.022 14.3 0.1 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Lysine exporter LysO Kinesin PF00225.23 EIM85510.1 - 3.8e-108 361.4 0.0 6.1e-108 360.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 EIM85510.1 - 5.9e-42 143.9 0.2 1.6e-41 142.5 0.2 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EIM85510.1 - 1.2e-39 136.3 11.8 3.2e-32 112.1 2.9 3.3 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 EIM85510.1 - 3.3e-21 75.8 0.0 8.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 EIM85510.1 - 2.2e-08 34.6 0.0 1.5e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 PH domain FHA PF00498.26 EIM85510.1 - 7e-08 32.7 0.1 3.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EIM85510.1 - 0.021 15.2 0.0 0.064 13.6 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF3896 PF13035.6 EIM85510.1 - 0.098 12.8 1.2 0.26 11.5 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) UPF0242 PF06785.11 EIM85510.1 - 0.76 9.8 14.8 0.97 9.5 5.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3037 PF11236.8 EIM85510.1 - 0.83 10.1 7.2 1.9 8.9 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3037) EAP30 PF04157.16 EIM85510.1 - 2.9 7.1 8.9 0.086 12.1 0.4 2.7 3 0 0 3 3 3 0 EAP30/Vps36 family PilJ PF13675.6 EIM85510.1 - 4.9 7.2 12.0 0.12 12.4 1.2 3.5 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term YgaB PF14182.6 EIM85510.1 - 5.3 7.5 12.9 0.41 11.1 4.5 2.5 2 0 0 2 2 2 0 YgaB-like protein Med26 PF08711.11 EIM85511.1 - 6.6e-07 29.3 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LIM_bind PF01803.16 EIM85512.1 - 3.1e-36 125.1 0.0 3.6e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 LIM-domain binding protein Ribosomal_S4 PF00163.19 EIM85513.1 - 1.1e-13 51.8 0.4 1.6e-13 51.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EIM85513.1 - 1.5e-11 43.8 0.0 2.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 S4 domain Herpes_LAMP2 PF06126.11 EIM85513.1 - 0.05 12.2 0.0 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 LPD38 PF18857.1 EIM85514.1 - 0.035 14.3 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 DSPn PF14671.6 EIM85517.1 - 2.3e-41 141.5 0.0 1.3e-39 135.9 0.0 2.6 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EIM85517.1 - 4.6e-15 55.6 0.0 7.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIM85517.1 - 0.00013 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EIM85517.1 - 0.00055 20.1 0.0 0.0008 19.5 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Tti2 PF10521.9 EIM85518.1 - 1.8e-45 155.7 0.0 2.3e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Tti2 family DUF3385 PF11865.8 EIM85518.1 - 0.15 11.9 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) p450 PF00067.22 EIM85519.1 - 2e-67 227.9 0.0 7.7e-67 226.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM85520.1 - 1.9e-69 234.6 0.0 4.6e-69 233.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM85521.1 - 2.1e-84 284.0 0.0 2.5e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EIM85521.1 - 1.2e-28 100.2 0.0 2.4e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EIM85521.1 - 6.5e-24 84.8 0.0 1.5e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EIM85521.1 - 6.3e-10 39.7 0.0 1.3e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EIM85521.1 - 0.016 15.4 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.11 EIM85521.1 - 0.086 13.0 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 NrdI Flavodoxin like SNF2_N PF00176.23 EIM85522.1 - 9.3e-48 162.7 0.0 1.1e-39 136.2 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM85522.1 - 4.5e-14 52.7 0.0 2e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM85522.1 - 8.8e-06 25.8 1.7 3.3e-05 23.9 0.1 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EIM85522.1 - 0.0001 22.1 4.3 0.0001 22.1 4.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM85522.1 - 0.00014 22.1 5.6 0.00014 22.1 5.6 2.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM85522.1 - 0.00049 19.9 4.5 0.00049 19.9 4.5 2.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EIM85522.1 - 0.00096 19.0 0.1 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 EIM85522.1 - 0.0034 17.2 4.1 0.0034 17.2 4.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM85522.1 - 0.0044 17.3 3.1 0.012 15.9 3.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EIM85522.1 - 0.0046 16.8 2.9 0.012 15.4 2.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit eIF3_subunit PF08597.10 EIM85522.1 - 0.055 13.4 8.3 0.1 12.5 8.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit HABP4_PAI-RBP1 PF04774.15 EIM85522.1 - 0.34 11.8 4.4 0.74 10.7 4.4 1.6 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family WW PF00397.26 EIM85523.1 - 2.2e-09 37.2 6.2 4.1e-09 36.4 6.2 1.5 1 0 0 1 1 1 1 WW domain HMG_box PF00505.19 EIM85524.1 - 4e-16 59.2 1.8 1e-15 57.9 1.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM85524.1 - 5.7e-10 39.6 1.6 1.5e-09 38.3 1.6 1.7 1 0 0 1 1 1 1 HMG-box domain SAPS PF04499.15 EIM85524.1 - 2 7.1 4.5 2.7 6.7 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SR-25 PF10500.9 EIM85524.1 - 9.6 5.7 26.5 0.23 11.0 18.2 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.7 EIM85525.1 - 3.6e-09 36.4 0.1 1.3e-08 34.6 0.1 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM85525.1 - 0.05 14.1 0.4 31 5.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Zn_Tnp_IS1595 PF12760.7 EIM85526.1 - 3.1 7.9 6.7 5.5 7.1 0.5 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_L44 PF00935.19 EIM85526.1 - 6.5 7.3 6.8 2.4 8.7 0.6 2.6 2 0 0 2 2 2 0 Ribosomal protein L44 zinc-ribbons_6 PF07191.12 EIM85526.1 - 6.8 6.7 7.7 9.8 6.2 2.4 2.4 2 0 0 2 2 2 0 zinc-ribbons NDUFA12 PF05071.16 EIM85527.1 - 2.5e-33 114.8 2.2 3.3e-33 114.4 2.2 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DAO PF01266.24 EIM85528.1 - 5.9e-35 121.5 0.0 7.4e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase XET_C PF06955.12 EIM85528.1 - 0.18 11.7 0.1 0.46 10.4 0.1 1.6 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus p450 PF00067.22 EIM85529.1 - 1.2e-64 218.8 0.0 1.4e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM85531.1 - 7.2e-68 229.4 0.0 8.7e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEC1 PF15859.5 EIM85531.1 - 0.064 13.3 0.0 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Deleted in esophageal cancer 1 family Trs65 PF12735.7 EIM85532.1 - 4.7e-23 82.1 0.0 1.3e-14 54.4 0.1 3.6 2 2 1 3 3 3 3 TRAPP trafficking subunit Trs65 Internalin_N PF12354.8 EIM85532.1 - 0.2 11.8 0.7 0.43 10.7 0.7 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Ribosomal_L12 PF00542.19 EIM85536.1 - 4e-21 75.1 5.6 1.1e-19 70.6 4.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EIM85536.1 - 1.8e-14 53.2 7.2 3.8e-14 52.1 2.8 2.5 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF4587 PF15248.6 EIM85536.1 - 0.091 13.6 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) Ribosomal_60s PF00428.19 EIM85536.1 - 2.6 8.7 10.4 0.62 10.7 6.6 2.0 1 1 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S7e PF01251.18 EIM85537.1 - 9.9e-87 289.5 3.5 1.8e-86 288.6 3.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_1 PF00515.28 EIM85537.1 - 8.2e-11 41.2 2.8 0.0039 16.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM85537.1 - 3.7e-07 29.8 2.9 0.3 11.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM85537.1 - 9.9e-05 22.9 0.3 0.17 12.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM85537.1 - 0.0032 17.9 1.5 0.031 14.8 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM85537.1 - 0.01 16.1 0.2 7.8 6.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM85537.1 - 0.051 14.4 0.3 16 6.7 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM85537.1 - 0.13 12.0 1.5 12 5.7 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TBD PF12845.7 EIM85537.1 - 0.16 11.9 1.2 17 5.4 0.4 3.2 3 0 0 3 3 3 0 TBD domain TPR_17 PF13431.6 EIM85537.1 - 0.16 12.4 1.3 0.58 10.7 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM85537.1 - 0.16 12.2 1.1 0.36 11.1 0.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.22 EIM85538.1 - 6.1e-46 156.0 0.1 6.4e-43 146.2 0.1 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EIM85538.1 - 4.2e-33 114.1 0.5 7.8e-33 113.2 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM85538.1 - 2.8e-11 43.2 0.1 4.8e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM85538.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIM85538.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIM85538.1 - 0.00077 18.9 0.1 0.003 17.0 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EIM85538.1 - 0.0014 18.4 0.1 0.012 15.4 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EIM85538.1 - 0.0051 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM85538.1 - 0.011 16.1 0.0 0.036 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EIM85538.1 - 0.017 15.1 0.8 0.045 13.6 0.0 2.1 3 1 1 4 4 4 0 RsgA GTPase AAA_7 PF12775.7 EIM85538.1 - 0.034 13.7 0.3 0.057 12.9 0.3 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EIM85538.1 - 0.035 13.4 0.2 0.19 10.9 0.1 1.9 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 EIM85538.1 - 0.039 14.0 0.1 0.085 12.9 0.0 1.7 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EIM85538.1 - 0.049 13.3 0.2 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EIM85538.1 - 0.14 11.7 0.1 0.91 9.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EIM85538.1 - 0.15 12.1 0.2 0.8 9.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EIM85538.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 EIM85538.1 - 0.21 11.0 0.1 0.48 9.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Ribosomal_L3 PF00297.22 EIM85540.1 - 3.4e-187 621.9 9.8 3.8e-187 621.7 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_3 PF13812.6 EIM85541.1 - 9.3e-14 51.3 0.0 5.8e-07 29.5 0.0 3.8 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 EIM85541.1 - 9e-11 41.8 2.4 1.8 8.8 0.0 6.5 5 1 1 6 6 6 5 PPR repeat family PPR PF01535.20 EIM85541.1 - 1.3e-06 28.2 2.9 0.12 12.6 0.1 6.0 6 1 0 6 6 6 1 PPR repeat PPR_long PF17177.4 EIM85541.1 - 0.0075 15.7 0.0 0.061 12.7 0.0 2.4 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EIM85541.1 - 0.011 15.5 4.5 0.24 11.1 0.2 3.6 3 0 0 3 3 3 0 PPR repeat Exosortase_EpsH PF09721.10 EIM85542.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) Pex2_Pex12 PF04757.14 EIM85544.1 - 1.9e-19 70.2 3.2 3.8e-19 69.2 2.7 1.6 1 1 1 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EIM85544.1 - 7.2e-07 29.0 0.4 1.1e-06 28.4 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM85544.1 - 2.3e-06 27.3 0.3 3.6e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM85544.1 - 0.00011 22.5 0.3 0.00017 21.8 0.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM85544.1 - 0.0011 19.0 1.3 0.0019 18.2 1.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM85544.1 - 0.003 17.7 2.4 0.0051 16.9 2.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EIM85544.1 - 0.0086 15.9 0.5 0.085 12.7 1.1 2.0 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EIM85544.1 - 0.01 15.7 0.5 0.016 15.1 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3797 PF12677.7 EIM85544.1 - 0.22 11.4 2.0 1.1 9.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-RING_5 PF14634.6 EIM85544.1 - 0.38 10.7 3.1 6.4 6.8 4.0 2.1 1 1 1 2 2 2 0 zinc-RING finger domain His_Phos_2 PF00328.22 EIM85545.1 - 6.8e-53 180.4 0.0 1.2e-52 179.6 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AMMECR1 PF01871.17 EIM85546.1 - 4.2e-44 150.1 0.0 5.7e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 MRC1 PF09444.10 EIM85548.1 - 4.2e-25 89.0 19.9 4.2e-25 89.0 19.9 7.6 6 1 1 7 7 7 2 MRC1-like domain Ank_2 PF12796.7 EIM85549.1 - 4e-36 123.5 0.0 7.3e-12 45.7 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM85549.1 - 1.9e-29 101.6 6.4 1.7e-07 31.6 0.7 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM85549.1 - 9.9e-22 74.7 8.5 0.00053 20.2 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat SPX PF03105.19 EIM85549.1 - 1.1e-21 78.3 28.7 3.3e-14 53.6 0.6 4.6 2 2 0 3 3 3 2 SPX domain Ank_5 PF13857.6 EIM85549.1 - 2.6e-20 72.2 9.6 7.5e-06 26.1 0.1 7.6 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EIM85549.1 - 1.3e-18 66.5 11.6 0.00027 21.2 0.0 7.3 8 0 0 8 8 8 5 Ankyrin repeat GDPD PF03009.17 EIM85549.1 - 5.6e-14 52.5 0.0 3.3e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.27 EIM85550.1 - 2e-20 73.7 0.0 4.7e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIM85550.1 - 1.5e-11 44.7 0.2 5.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIM85550.1 - 0.00014 21.4 0.0 0.0075 15.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EIM85550.1 - 0.00028 20.7 0.0 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM85550.1 - 0.0011 19.2 0.2 0.28 11.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 EIM85550.1 - 0.0012 19.1 0.0 0.0075 16.5 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EIM85550.1 - 0.0032 17.2 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EIM85550.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EIM85550.1 - 0.07 13.5 0.3 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EIM85550.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EIM85550.1 - 0.1 11.2 0.0 2 6.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EIM85550.1 - 0.13 12.1 0.0 0.57 10.1 0.0 2.2 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EIM85550.1 - 0.16 12.5 0.1 0.28 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIM85550.1 - 0.25 10.9 0.7 1.3 8.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain GTP_cyclohydroI PF01227.22 EIM85551.1 - 9.6e-76 253.2 0.6 1.1e-75 253.0 0.6 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EIM85551.1 - 0.00032 20.8 0.0 0.0013 18.9 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 EIM85551.1 - 0.02 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain THOC2_N PF16134.5 EIM85552.1 - 4.3e-142 475.0 0.0 8.2e-142 474.0 0.0 1.4 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EIM85552.1 - 2.5e-88 296.2 0.0 4.2e-88 295.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EIM85552.1 - 9.9e-27 92.8 0.0 2.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Corona_NS1 PF06145.11 EIM85555.1 - 0.098 12.2 0.1 0.27 10.8 0.1 1.7 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 AAA_16 PF13191.6 EIM85556.1 - 0.068 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Pex2_Pex12 PF04757.14 EIM85557.1 - 5.9e-49 166.7 5.4 7e-49 166.4 5.4 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EIM85557.1 - 1.6e-06 27.9 0.3 2.3e-06 27.3 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM85557.1 - 4.2e-06 26.5 0.2 6.5e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM85557.1 - 0.00041 20.6 0.2 0.00068 19.9 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM85557.1 - 0.0016 18.4 1.1 0.003 17.6 1.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM85557.1 - 0.0061 16.7 2.2 0.011 15.9 2.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EIM85557.1 - 0.024 14.5 0.3 0.038 13.9 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM85557.1 - 0.044 13.7 0.3 0.31 10.9 0.5 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3797 PF12677.7 EIM85557.1 - 0.33 10.9 2.4 1.4 8.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-RING_5 PF14634.6 EIM85557.1 - 0.67 10.0 2.7 11 6.1 3.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Rubredoxin_2 PF18073.1 EIM85557.1 - 1.3 8.9 4.8 12 5.7 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Haem_degrading PF03928.14 EIM85558.1 - 0.0019 18.3 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 Haem-degrading SSB PF00436.25 EIM85559.1 - 1.4e-17 63.6 0.0 1.7e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family HBS1_N PF08938.10 EIM85560.1 - 4.4e-14 52.5 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.27 EIM85561.1 - 2.3e-33 115.4 0.0 2.9e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIM85561.1 - 7.3e-14 52.0 0.0 3.2e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EIM85561.1 - 2.9e-05 24.4 0.0 6.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM85561.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AMPK1_CBM PF16561.5 EIM85562.1 - 4.8e-18 65.2 0.2 8.4e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase adh_short_C2 PF13561.6 EIM85563.1 - 5.3e-61 206.2 1.5 6e-61 206.0 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM85563.1 - 8.3e-53 178.7 0.5 1e-52 178.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM85563.1 - 5.6e-09 36.2 1.1 1.4e-08 34.9 1.1 1.6 1 1 0 1 1 1 1 KR domain Pkinase PF00069.25 EIM85564.1 - 1.8e-11 44.0 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM85564.1 - 1.4e-06 28.4 0.4 3.4e-06 27.2 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EIM85564.1 - 8.8e-06 25.2 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EIM85564.1 - 1.2e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM85564.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIM85564.1 - 0.0032 16.3 0.0 0.0038 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EIM85564.1 - 0.0043 16.7 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EIM85564.1 - 0.083 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Med25_NR-box PF11244.8 EIM85565.1 - 0.054 13.9 0.4 0.054 13.9 0.4 2.6 2 1 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing EF-hand_1 PF00036.32 EIM85567.1 - 3.1e-26 88.9 12.8 1.4e-07 30.5 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EIM85567.1 - 7.8e-22 77.5 6.1 4.3e-12 46.3 1.7 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EIM85567.1 - 4.7e-20 69.8 7.8 4e-05 23.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EIM85567.1 - 5.9e-17 60.3 13.9 3.8e-06 26.2 0.4 4.4 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EIM85567.1 - 9.6e-13 47.8 14.9 0.0005 19.9 1.1 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EIM85567.1 - 5e-06 26.8 0.1 0.018 15.3 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EIM85567.1 - 0.00024 21.0 7.0 0.011 15.6 1.0 3.5 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand Nse4-Nse3_bdg PF15412.6 EIM85567.1 - 0.091 12.9 2.5 3.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE MnmE_helical PF12631.7 EIM85568.1 - 1.6e-41 142.8 0.0 2.3e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EIM85568.1 - 1.6e-35 121.9 0.0 4.4e-35 120.5 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EIM85568.1 - 1.7e-17 63.5 0.0 3.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EIM85568.1 - 5.7e-05 23.2 0.0 0.0002 21.4 0.0 2.0 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EIM85568.1 - 0.00032 20.3 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIM85568.1 - 0.032 14.2 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EIM85568.1 - 0.038 14.5 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EIM85568.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MARVEL PF01284.23 EIM85569.1 - 2.1e-08 34.3 16.4 2.1e-08 34.3 16.4 1.7 1 1 1 2 2 2 1 Membrane-associating domain WD40 PF00400.32 EIM85570.1 - 0.0028 18.5 0.6 0.0056 17.5 0.6 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM85570.1 - 0.0099 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Pex2_Pex12 PF04757.14 EIM85571.1 - 9.3e-37 126.8 4.0 1.1e-36 126.6 4.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EIM85571.1 - 1.2e-06 28.2 0.3 1.8e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM85571.1 - 3.3e-06 26.8 0.2 5e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM85571.1 - 0.00032 21.0 0.2 0.00053 20.3 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM85571.1 - 0.0013 18.7 1.1 0.0023 17.9 1.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM85571.1 - 0.0046 17.1 2.2 0.0082 16.3 2.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EIM85571.1 - 0.019 14.8 0.3 0.03 14.2 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM85571.1 - 0.031 14.1 0.3 0.26 11.2 0.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3797 PF12677.7 EIM85571.1 - 0.22 11.4 2.4 1.1 9.1 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-RING_5 PF14634.6 EIM85571.1 - 0.46 10.5 2.7 8.8 6.4 3.8 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Rubredoxin_2 PF18073.1 EIM85571.1 - 0.82 9.4 4.8 9.6 6.0 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Corona_NS1 PF06145.11 EIM85573.1 - 0.076 12.5 0.1 0.22 11.0 0.1 1.8 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 WD40 PF00400.32 EIM85576.1 - 2.6e-08 34.4 15.7 0.0025 18.6 0.0 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM85576.1 - 0.0015 18.8 0.6 0.17 12.2 0.1 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4199 PF13858.6 EIM85578.1 - 0.57 10.6 14.6 0.31 11.4 1.8 2.7 1 1 0 3 3 3 0 Protein of unknown function (DUF4199) DUF3959 PF13105.6 EIM85578.1 - 0.78 9.2 5.8 0.17 11.3 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) MARVEL PF01284.23 EIM85579.1 - 3.8e-07 30.2 5.6 7e-07 29.4 5.6 1.4 1 0 0 1 1 1 1 Membrane-associating domain MBOAT PF03062.19 EIM85580.1 - 1.9e-45 155.8 5.3 8.4e-45 153.6 5.3 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.11 EIM85580.1 - 0.044 14.1 0.1 4.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) Ribosomal_L18 PF17135.4 EIM85581.1 - 5.9e-87 289.9 2.8 6.5e-87 289.8 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EIM85581.1 - 0.0015 19.2 0.1 0.0015 19.2 0.1 2.0 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Adenylate_cycl PF01295.18 EIM85581.1 - 0.18 10.4 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I RRM_1 PF00076.22 EIM85582.1 - 3.1e-17 62.2 0.0 4.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM85582.1 - 0.00012 21.6 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM85582.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif Glyco_hydro_28 PF00295.17 EIM85583.1 - 6.5e-63 212.7 24.2 7.8e-63 212.5 24.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TOBE_2 PF08402.10 EIM85583.1 - 0.14 12.3 1.0 11 6.3 0.0 3.0 3 0 0 3 3 3 0 TOBE domain ACBP PF00887.19 EIM85584.1 - 1.7e-13 50.6 0.1 2.6e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein SlyX PF04102.12 EIM85584.1 - 0.073 13.7 2.5 15 6.2 0.8 2.6 2 0 0 2 2 2 0 SlyX MRP-S34 PF16053.5 EIM85585.1 - 7.2e-11 41.8 0.5 1e-10 41.4 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Psu PF07455.11 EIM85586.1 - 0.079 12.5 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) Ank_2 PF12796.7 EIM85587.1 - 1.1e-17 64.4 0.1 6.4e-09 36.3 0.0 3.0 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM85587.1 - 3.3e-16 59.4 4.0 2.5e-09 37.5 0.1 4.1 3 2 2 5 5 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EIM85587.1 - 2.4e-15 56.2 0.4 2.3e-06 27.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EIM85587.1 - 5.3e-13 48.9 0.0 7.6e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM85587.1 - 6.4e-12 44.6 0.3 0.00014 22.0 0.1 4.1 4 0 0 4 4 3 2 Ankyrin repeat KilA-N PF04383.13 EIM85587.1 - 0.00033 20.5 0.1 0.0044 16.8 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain CENP-Q PF13094.6 EIM85587.1 - 0.032 14.4 0.3 0.069 13.4 0.3 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit KxDL PF10241.9 EIM85587.1 - 0.046 14.0 2.6 0.083 13.2 1.9 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.8 EIM85587.1 - 0.83 9.9 5.1 2.9 8.2 3.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 EIM85587.1 - 1.3 9.1 5.0 1.7 8.7 3.9 1.7 2 0 0 2 2 2 0 Laminin Domain II OmpH PF03938.14 EIM85587.1 - 5.9 7.2 8.1 2.1 8.7 4.7 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.32 EIM85588.1 - 2.1e-19 69.5 12.2 4.6e-06 27.3 2.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM85588.1 - 1.3e-05 25.3 0.1 2.4 8.5 0.0 4.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM85588.1 - 0.00017 21.5 0.1 0.16 11.8 0.0 3.1 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EIM85588.1 - 0.0027 15.8 0.0 0.024 12.7 0.0 2.0 1 1 0 2 2 2 1 IKI3 family PALB2_WD40 PF16756.5 EIM85588.1 - 0.029 13.3 0.6 0.21 10.5 0.2 2.2 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain BBS2_N PF14781.6 EIM85588.1 - 0.069 13.1 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal WD40_like PF17005.5 EIM85588.1 - 0.17 11.2 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain EMC3_TMCO1 PF01956.16 EIM85589.1 - 0.11 12.2 2.5 0.14 11.9 2.5 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2252 PF10009.9 EIM85589.1 - 0.13 11.3 0.1 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DEAD PF00270.29 EIM85590.1 - 2.8e-38 131.4 0.0 9.9e-38 129.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM85590.1 - 3.7e-23 82.0 0.1 9.6e-23 80.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EIM85590.1 - 1.5e-20 73.2 3.3 1.5e-20 73.2 3.3 2.6 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Nucleoside_tran PF01733.18 EIM85591.1 - 9.4e-38 130.3 6.1 4e-35 121.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoside transporter Glu-tRNAGln PF02686.15 EIM85592.1 - 0.00021 21.5 0.4 0.00093 19.4 0.4 2.0 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF4455 PF14643.6 EIM85592.1 - 0.11 11.1 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Peptidase_M43 PF05572.13 EIM85593.1 - 2e-17 63.5 0.1 3.6e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EIM85593.1 - 3.4e-07 30.6 0.6 4.9e-07 30.1 0.6 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EIM85593.1 - 2.1e-06 28.3 0.1 4.2e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EIM85593.1 - 0.00052 19.7 0.9 0.00052 19.7 0.9 2.6 1 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 EIM85593.1 - 0.0011 19.0 0.6 0.0034 17.5 0.6 1.8 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 EIM85593.1 - 0.049 12.6 0.2 0.082 11.8 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 EIM85593.1 - 0.065 12.4 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Met-zincin Reprolysin_2 PF13574.6 EIM85593.1 - 0.32 10.9 4.2 0.44 10.4 4.0 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EIM85593.1 - 0.49 10.0 8.8 0.41 10.2 4.4 2.1 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase Vfa1 PF08432.10 EIM85594.1 - 1.1e-37 130.1 0.0 1.2e-37 130.0 0.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 ADH_N PF08240.12 EIM85595.1 - 3.3e-24 84.9 2.9 6.6e-24 83.9 2.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM85595.1 - 1.7e-18 66.8 0.1 3.9e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EIM85595.1 - 0.00023 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EIM85595.1 - 0.00038 19.8 0.3 0.00072 18.9 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain dUTPase PF00692.19 EIM85596.1 - 1.3e-41 141.3 0.0 1.5e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase FAM176 PF14851.6 EIM85597.1 - 1.2 8.8 7.1 14 5.3 0.5 3.8 3 0 0 3 3 3 0 FAM176 family DUF4449 PF14613.6 EIM85598.1 - 8.6e-38 130.0 0.2 8.6e-38 130.0 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Peptidase_S10 PF00450.22 EIM85599.1 - 1.6e-76 258.4 1.9 4.5e-76 256.9 1.9 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase zf-U1 PF06220.12 EIM85600.1 - 3.4e-20 71.5 5.4 4.6e-20 71.1 5.4 1.2 1 0 0 1 1 1 1 U1 zinc finger CLPTM1 PF05602.12 EIM85601.1 - 2.2e-142 475.1 0.0 2.5e-142 474.9 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EIM85601.1 - 0.00071 19.3 0.2 0.0017 18.1 0.2 1.6 1 0 0 1 1 1 1 PQ loop repeat 2TM PF13239.6 EIM85601.1 - 0.079 13.3 0.2 0.079 13.3 0.2 2.0 2 0 0 2 2 2 0 2TM domain COesterase PF00135.28 EIM85602.1 - 8.1e-104 348.3 0.2 1.5e-103 347.4 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM85602.1 - 0.00058 19.8 0.8 0.0069 16.3 0.8 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold MAS20 PF02064.15 EIM85604.1 - 3.1e-39 134.0 0.1 7.1e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 MAS20 protein import receptor SET PF00856.28 EIM85604.1 - 1.1e-10 42.2 0.0 4.5e-10 40.2 0.0 2.0 2 1 0 2 2 2 1 SET domain AAA PF00004.29 EIM85605.1 - 3.4e-20 72.8 0.0 7.2e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM85605.1 - 0.024 15.0 0.5 3.7 7.9 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 EIM85605.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EIM85605.1 - 0.055 13.7 0.3 1.6 9.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain PaaX_C PF08223.11 EIM85605.1 - 0.094 13.0 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain AAA_30 PF13604.6 EIM85605.1 - 0.23 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_hydro_79C PF16862.5 EIM85606.1 - 3.9e-10 40.5 1.7 9.2e-10 39.3 0.5 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain GN3L_Grn1 PF08701.11 EIM85608.1 - 3.7e-21 75.0 21.1 1.6e-20 72.9 21.1 2.2 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EIM85608.1 - 3.4e-12 46.4 0.0 4.3e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EIM85608.1 - 1.1e-05 25.6 7.6 0.00031 20.8 0.4 3.7 3 1 1 4 4 4 1 Dynamin family AIG1 PF04548.16 EIM85608.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 EIM85608.1 - 0.00052 19.4 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EIM85608.1 - 0.0011 18.5 0.0 0.74 9.3 0.1 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain YL1 PF05764.13 EIM85608.1 - 0.0023 18.1 14.6 0.0023 18.1 14.6 3.2 2 1 0 2 2 1 1 YL1 nuclear protein RsgA_GTPase PF03193.16 EIM85608.1 - 0.0029 17.5 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EIM85608.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.13 EIM85608.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF463 PF04317.12 EIM85608.1 - 0.059 12.3 0.2 0.11 11.4 0.2 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_7 PF12775.7 EIM85608.1 - 0.066 12.7 0.1 9.2 5.7 0.2 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region FeoB_N PF02421.18 EIM85608.1 - 0.068 12.7 0.1 0.28 10.7 0.1 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 EIM85608.1 - 0.087 12.2 0.0 0.28 10.6 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CNDH2_C PF16858.5 EIM85608.1 - 0.37 10.6 14.7 1.3 8.8 5.8 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Lin-8 PF03353.15 EIM85608.1 - 9.8 5.6 18.5 0.17 11.4 7.9 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Calcipressin PF04847.12 EIM85609.1 - 0.17 11.7 0.5 0.25 11.1 0.5 1.3 1 0 0 1 1 1 0 Calcipressin HIG_1_N PF04588.13 EIM85612.1 - 1.7e-05 24.9 2.4 3.7e-05 23.8 2.4 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2162 PF09930.9 EIM85612.1 - 0.028 13.9 0.4 0.042 13.3 0.4 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Bax1-I PF01027.20 EIM85612.1 - 0.074 12.9 1.1 0.094 12.5 0.1 1.6 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 UQ_con PF00179.26 EIM85613.1 - 1.3e-15 57.2 0.1 1.9e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MliC PF09864.9 EIM85614.1 - 0.033 14.1 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DUF4962 PF16332.5 EIM85614.1 - 0.043 12.3 9.6 0.067 11.7 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) WD40 PF00400.32 EIM85615.1 - 2.4e-62 205.4 34.2 3.3e-11 43.5 0.2 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM85615.1 - 2.4e-23 82.2 5.4 0.00057 20.1 0.0 7.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EIM85615.1 - 5.3e-10 39.3 16.1 1.4e-05 24.8 7.5 2.7 1 1 1 2 2 2 2 PQQ-like domain NACHT PF05729.12 EIM85615.1 - 5.4e-10 39.4 0.0 2e-09 37.6 0.0 2.0 2 0 0 2 2 1 1 NACHT domain eIF2A PF08662.11 EIM85615.1 - 4.8e-08 33.1 0.0 0.039 13.8 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EIM85615.1 - 1.5e-06 27.0 9.1 0.0022 16.6 0.1 4.2 1 1 4 5 5 5 4 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EIM85615.1 - 1.8e-06 27.2 4.3 2.1 7.2 0.0 5.9 3 2 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EIM85615.1 - 2.5e-06 28.0 0.3 2.8e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain WD40_like PF17005.5 EIM85615.1 - 1.7e-05 24.3 0.2 2.5 7.3 0.0 3.7 3 1 0 3 3 3 3 WD40-like domain Me-amine-dh_H PF06433.11 EIM85615.1 - 2.5e-05 23.3 0.4 0.2 10.5 0.0 3.4 1 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.21 EIM85615.1 - 0.00099 18.9 0.0 6.1 7.0 0.0 4.6 5 0 0 5 5 4 1 PQQ enzyme repeat AAA_22 PF13401.6 EIM85615.1 - 0.011 16.0 0.0 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIM85615.1 - 0.017 15.5 0.1 0.19 12.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase PQQ_3 PF13570.6 EIM85615.1 - 0.037 14.5 9.2 16 6.1 0.0 6.0 5 1 1 6 6 6 0 PQQ-like domain PD40 PF07676.12 EIM85615.1 - 0.043 13.8 0.0 51 4.0 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF5114 PF17141.4 EIM85615.1 - 0.077 13.5 0.2 36 5.0 0.0 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF5114) CHAP PF05257.16 EIM85615.1 - 0.078 13.6 14.2 1.9 9.1 0.1 5.3 2 1 4 6 6 5 0 CHAP domain AAA PF00004.29 EIM85615.1 - 0.1 13.0 0.0 0.46 10.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Big_7 PF17957.1 EIM85615.1 - 5.5 7.8 13.5 11 6.8 0.2 5.2 5 1 1 6 6 5 0 Bacterial Ig domain RRM_1 PF00076.22 EIM85616.1 - 1.3e-17 63.4 0.2 1.1e-08 34.7 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM85616.1 - 0.001 18.6 0.0 0.008 15.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM85616.1 - 0.063 13.1 0.0 0.51 10.2 0.0 2.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRN3 PF05327.11 EIM85616.1 - 0.24 9.9 0.2 0.33 9.4 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Roughex PF06020.11 EIM85616.1 - 0.47 9.5 4.4 0.65 9.0 4.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TRAM_LAG1_CLN8 PF03798.16 EIM85617.1 - 2.3e-43 148.3 19.7 3.1e-43 147.8 19.7 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EIM85617.1 - 1.8e-09 37.1 0.9 3.3e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.22 EIM85618.1 - 4.6e-18 64.8 0.2 2e-10 40.4 0.1 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM85618.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Sporozoite_P67 PF05642.11 EIM85618.1 - 0.42 8.6 22.0 0.052 11.6 16.9 1.9 1 1 0 2 2 2 0 Sporozoite P67 surface antigen PGA2 PF07543.12 EIM85618.1 - 0.93 9.5 7.5 0.12 12.3 2.8 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 Nucleo_P87 PF07267.11 EIM85618.1 - 1.3 7.8 6.2 1.7 7.4 6.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 YL1 PF05764.13 EIM85618.1 - 3.8 7.6 21.0 0.38 10.8 13.6 2.4 2 0 0 2 2 2 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 EIM85618.1 - 3.9 7.9 12.7 11 6.4 12.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EIM85618.1 - 4.7 6.4 5.7 9.4 5.5 5.7 1.4 1 0 0 1 1 1 0 NOA36 protein Amino_oxidase PF01593.24 EIM85619.1 - 1.5e-41 143.1 0.0 1.9e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIM85619.1 - 1.7e-07 31.4 0.0 7.7e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EIM85619.1 - 0.044 13.1 0.1 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 EIM85620.1 - 2.4e-39 135.3 36.7 2.4e-39 135.3 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM85620.1 - 7e-11 41.2 1.9 1.1e-10 40.6 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 EIM85621.1 - 1.4e-52 179.0 0.0 3e-52 177.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.22 EIM85622.1 - 3.8e-78 263.5 0.0 5.1e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EIM85622.1 - 2.7e-32 110.8 0.0 6.1e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EIM85622.1 - 1.1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain E1-E2_ATPase PF00122.20 EIM85623.1 - 2.4e-50 170.6 0.1 2.4e-50 170.6 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EIM85623.1 - 1.3e-42 144.1 8.9 2.5e-13 50.3 0.0 4.7 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EIM85623.1 - 6.8e-37 127.8 0.4 1.5e-36 126.7 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EIM85623.1 - 1.3e-05 25.7 0.0 2.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.21 EIM85623.1 - 0.00062 19.7 0.0 0.062 13.2 0.0 3.0 3 0 0 3 3 3 1 AhpC/TSA family Hydrolase_3 PF08282.12 EIM85623.1 - 0.0015 18.3 0.1 0.018 14.8 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SNAD4 PF18750.1 EIM85623.1 - 0.0094 16.1 0.1 23 5.1 0.1 3.5 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 Spore_YhcN_YlaJ PF09580.10 EIM85623.1 - 0.015 15.4 3.6 0.15 12.1 2.5 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ACT_6 PF13740.6 EIM85623.1 - 0.067 13.2 3.6 8.2 6.5 0.1 3.6 3 0 0 3 3 3 0 ACT domain GFA PF04828.14 EIM85623.1 - 0.081 13.3 0.6 32 5.0 0.0 3.8 4 0 0 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme NAD1 PF18778.1 EIM85623.1 - 0.19 11.8 1.0 29 4.7 0.1 2.9 3 0 0 3 3 3 0 Novel AID APOBEC clade 1 GCP_N_terminal PF17681.1 EIM85624.1 - 2e-96 323.2 0.0 4.3e-96 322.1 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EIM85624.1 - 8.9e-82 275.0 0.8 8.9e-82 275.0 0.8 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal AMP-binding PF00501.28 EIM85625.1 - 5.3e-82 275.7 0.0 6.8e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM85625.1 - 1.1e-09 39.1 2.5 2.1e-09 38.2 2.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGAP_C PF03836.15 EIM85626.1 - 3.7e-46 156.7 1.1 3.7e-46 156.7 1.1 3.2 4 0 0 4 4 4 1 RasGAP C-terminus RasGAP PF00616.19 EIM85626.1 - 5.7e-43 147.1 0.0 1.5e-42 145.7 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EIM85626.1 - 7.2e-16 56.4 72.4 0.0091 15.7 0.7 13.9 13 0 0 13 13 13 10 IQ calmodulin-binding motif CH PF00307.31 EIM85626.1 - 5.9e-12 45.7 0.0 2e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain RPN1_C PF18051.1 EIM85626.1 - 0.011 15.8 0.8 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal Sipho_Gp157 PF05565.11 EIM85626.1 - 0.51 10.3 4.0 0.64 10.0 0.4 2.7 2 0 0 2 2 2 0 Siphovirus Gp157 HHH_7 PF14635.6 EIM85626.1 - 0.58 10.5 2.3 0.67 10.3 0.4 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif UCMA PF17085.5 EIM85626.1 - 3.8 7.5 8.8 0.39 10.7 1.0 3.0 3 0 0 3 3 3 0 Unique cartilage matrix associated protein PPR_2 PF13041.6 EIM85628.1 - 3.7e-18 65.5 0.1 8.4e-13 48.3 0.1 3.9 3 0 0 3 3 3 3 PPR repeat family PPR PF01535.20 EIM85628.1 - 8.6e-14 50.7 5.6 0.0068 16.6 0.0 6.8 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.7 EIM85628.1 - 2e-10 40.2 0.2 0.00053 19.6 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 EIM85628.1 - 0.00014 21.8 0.0 0.00087 19.3 0.0 2.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EIM85628.1 - 0.00023 20.6 0.0 0.14 11.5 0.0 3.0 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP Ham1p_like PF01725.16 EIM85628.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Ham1 family Ribophorin_I PF04597.14 EIM85630.1 - 2.4e-127 425.8 0.1 2.8e-127 425.6 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L22 PF00237.19 EIM85631.1 - 5.1e-24 84.5 0.4 9.5e-24 83.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GILT PF03227.16 EIM85632.1 - 2e-17 63.4 0.4 3.4e-17 62.6 0.4 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) TGBp3 PF02495.17 EIM85632.1 - 0.032 13.9 0.2 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 Triple gene block 3 Cid2 PF09774.9 EIM85633.1 - 7.1e-28 98.0 4.5 7.3e-27 94.7 4.5 1.9 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Peptidase_M90 PF06167.12 EIM85633.1 - 0.049 13.2 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 NAD_Gly3P_dh_N PF01210.23 EIM85633.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-H2C2_2 PF13465.6 EIM85634.1 - 0.00014 22.1 1.3 0.00014 22.1 1.3 2.5 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM85634.1 - 0.0066 17.2 6.7 0.0066 17.2 6.7 2.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EIM85634.1 - 0.033 14.7 7.5 0.033 14.7 7.5 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type RNR_inhib PF08591.10 EIM85635.1 - 1.4e-05 26.4 0.1 3.5e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Kelch_4 PF13418.6 EIM85636.1 - 2.1e-15 56.5 11.5 0.0029 17.6 0.1 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EIM85636.1 - 7.8e-13 48.4 26.4 0.00045 20.4 0.1 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EIM85636.1 - 4e-05 23.1 6.5 0.13 11.9 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EIM85636.1 - 5.3e-05 23.4 7.6 0.37 11.1 0.0 5.8 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 EIM85636.1 - 0.0095 15.9 5.3 21 5.2 0.2 5.0 5 0 0 5 5 5 2 Kelch motif LID PF17916.1 EIM85637.1 - 2.2 8.0 6.7 0.37 10.5 2.1 2.1 2 0 0 2 2 2 0 LIM interaction domain (LID) HSP90 PF00183.18 EIM85638.1 - 4.5e-134 448.2 5.7 5.6e-134 447.9 5.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EIM85638.1 - 7e-09 35.6 0.0 1.9e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EIM85638.1 - 1.8e-07 31.6 0.0 4.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN_RiboL-PSP PF18735.1 EIM85638.1 - 0.09 12.7 0.6 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 RiboL-PSP-HEPN MerB PF03243.15 EIM85638.1 - 0.1 12.7 0.0 0.82 9.8 0.0 2.2 2 0 0 2 2 2 0 Alkylmercury lyase DUF4827 PF16109.5 EIM85638.1 - 0.11 12.5 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) PduV-EutP PF10662.9 EIM85638.1 - 0.17 11.6 0.1 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FF PF01846.19 EIM85639.1 - 6.3e-39 131.9 18.8 1.7e-10 40.9 0.0 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.26 EIM85639.1 - 6.9e-08 32.4 5.3 2.8e-05 24.1 0.7 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EIM85639.1 - 2.9e-07 31.1 9.2 0.034 14.8 0.0 4.8 3 2 1 4 4 4 3 p190-A and -B Rho GAPs FF domain Peroxidase_2 PF01328.17 EIM85640.1 - 2.6e-53 181.3 0.0 3.2e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.16 EIM85641.1 - 6.3e-39 133.9 14.1 1e-38 133.2 14.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_8 PF13621.6 EIM85642.1 - 2.3e-15 57.0 0.0 8.3e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Peptidase_S10 PF00450.22 EIM85643.1 - 2e-97 327.3 0.0 2.6e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Connexin PF00029.19 EIM85644.1 - 0.013 15.3 0.2 0.02 14.6 0.2 1.2 1 0 0 1 1 1 0 Connexin DUF2681 PF10883.8 EIM85644.1 - 0.1 13.0 1.2 0.19 12.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ATP-synt_E PF05680.12 EIM85644.1 - 0.2 12.0 5.4 0.41 11.0 5.4 1.5 1 0 0 1 1 1 0 ATP synthase E chain SNF2_N PF00176.23 EIM85645.1 - 1.4e-64 218.1 0.3 2.9e-64 217.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.11 EIM85645.1 - 1.1e-17 63.7 0.0 3.1e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EIM85645.1 - 1.6e-09 38.0 0.0 5.8e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM85645.1 - 5.2e-09 36.3 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EIM85645.1 - 7.8e-09 35.2 6.1 1.6e-08 34.2 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM85645.1 - 6.4e-08 32.3 5.3 1.2e-07 31.4 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM85645.1 - 3.2e-07 30.1 3.2 5.9e-07 29.3 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM85645.1 - 3.2e-05 24.2 6.0 5.9e-05 23.3 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EIM85645.1 - 4.1e-05 23.5 2.8 7.5e-05 22.6 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIM85645.1 - 7.6e-05 22.6 9.2 0.00016 21.6 9.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM85645.1 - 0.00023 21.2 6.8 0.00048 20.2 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.29 EIM85645.1 - 0.0007 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-rbx1 PF12678.7 EIM85645.1 - 0.0017 18.6 4.3 0.013 15.8 4.3 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-PARP PF00645.18 EIM85645.1 - 0.054 14.4 0.0 0.15 12.9 0.0 1.8 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WW PF00397.26 EIM85645.1 - 0.13 12.4 0.2 0.37 10.9 0.2 1.9 1 0 0 1 1 1 0 WW domain Prok-RING_4 PF14447.6 EIM85645.1 - 0.52 10.2 7.3 4.1 7.3 7.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 K-box PF01486.17 EIM85645.1 - 6.2 7.1 10.4 0.36 11.0 4.6 1.9 2 0 0 2 2 1 0 K-box region Mgm101p PF06420.12 EIM85646.1 - 7.3e-87 289.2 0.0 8.2e-87 289.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DASH_Spc19 PF08287.11 EIM85647.1 - 2.1e-27 96.0 12.3 1.7e-26 93.0 12.3 1.9 1 1 0 1 1 1 1 Spc19 Prefoldin_2 PF01920.20 EIM85647.1 - 0.0093 15.9 9.5 0.13 12.2 1.3 2.3 2 0 0 2 2 2 2 Prefoldin subunit DUF1319 PF07028.11 EIM85647.1 - 0.079 13.2 4.3 0.057 13.6 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) GIT_CC PF16559.5 EIM85647.1 - 0.43 10.5 7.2 0.21 11.5 1.8 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor NuA4 PF09340.10 EIM85647.1 - 2.9 7.8 7.2 0.48 10.3 3.1 1.8 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Prefoldin PF02996.17 EIM85647.1 - 3.5 7.5 8.6 2.2 8.2 1.8 2.7 2 1 0 3 3 3 0 Prefoldin subunit APG6_N PF17675.1 EIM85647.1 - 8.2 7.0 13.0 2 9.0 3.2 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region MoCF_biosynth PF00994.24 EIM85648.1 - 7.5e-59 197.5 0.4 6e-29 100.6 0.1 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EIM85648.1 - 1.7e-32 112.3 0.1 3e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EIM85648.1 - 5.1e-13 49.0 0.2 2.5e-12 46.8 0.0 2.3 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) UPF0180 PF03698.13 EIM85648.1 - 0.14 12.4 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) GDPD PF03009.17 EIM85651.1 - 5.2e-32 111.6 0.0 7.2e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EIM85651.1 - 0.042 14.3 0.8 0.14 12.6 0.2 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family OPT PF03169.15 EIM85652.1 - 7.4e-121 404.7 24.8 1.1e-120 404.2 24.8 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase_fungal PF17667.1 EIM85653.1 - 8.5e-45 153.2 0.0 5.7e-32 111.0 0.1 2.0 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EIM85653.1 - 6.5e-10 39.3 0.1 3.7e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EIM85653.1 - 0.00098 18.6 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Acyltransferase PF01553.21 EIM85654.1 - 1.2e-32 112.3 0.0 1.8e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Spermine_synth PF01564.17 EIM85655.1 - 5.1e-09 35.8 0.0 7.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain adh_short PF00106.25 EIM85656.1 - 7.6e-44 149.5 0.2 1.2e-43 148.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM85656.1 - 1.8e-27 96.4 0.0 2.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM85656.1 - 2.6e-12 47.0 1.1 6.4e-11 42.5 1.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM85656.1 - 0.037 13.5 0.1 0.061 12.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACT_7 PF13840.6 EIM85658.1 - 9.6e-20 70.1 0.0 5.9e-14 51.6 0.1 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 EIM85658.1 - 0.019 14.8 0.2 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain PGAP1 PF07819.13 EIM85659.1 - 1.2e-52 178.9 0.0 1.8e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EIM85659.1 - 0.00061 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM85659.1 - 0.002 18.8 0.1 0.002 18.8 0.1 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM85659.1 - 0.036 13.7 0.0 0.11 12.2 0.0 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.12 EIM85659.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 EIM85659.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) zf-LITAF-like PF10601.9 EIM85659.1 - 2.1 8.7 5.8 0.39 11.0 1.2 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Ribosomal_L29 PF00831.23 EIM85660.1 - 9.5e-19 67.1 2.2 9.5e-19 67.1 2.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein SNCAIP_SNCA_bd PF16700.5 EIM85660.1 - 0.028 14.1 0.7 0.069 12.9 0.7 1.6 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain DUF2870 PF11069.8 EIM85660.1 - 0.056 13.8 0.2 0.056 13.8 0.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2870) His_biosynth PF00977.21 EIM85661.1 - 4.3e-35 121.2 0.0 5.3e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Fe-ADH PF00465.19 EIM85662.1 - 3.3e-90 302.6 0.0 4.3e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EIM85662.1 - 1.4e-10 41.3 0.0 3.4e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Asp PF00026.23 EIM85663.1 - 5.6e-36 124.6 2.7 2.9e-35 122.2 2.7 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM85663.1 - 7.1e-07 29.6 3.7 0.00016 21.9 0.3 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM85663.1 - 0.0047 17.5 0.1 2.6 8.8 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease EphA2_TM PF14575.6 EIM85663.1 - 0.017 16.0 0.0 0.5 11.3 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EIM85663.1 - 0.021 14.8 2.3 0.024 14.5 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family BatD PF13584.6 EIM85663.1 - 0.045 12.6 0.1 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 Oxygen tolerance PepSY_TM PF03929.16 EIM85663.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Stevor PF17410.2 EIM85663.1 - 0.1 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame NOA36 PF06524.12 EIM85664.1 - 0.03 13.7 2.7 0.045 13.1 2.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EIM85664.1 - 0.47 8.6 4.3 0.67 8.1 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 EIM85666.1 - 8.5e-70 235.1 0.0 1.2e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85666.1 - 1.3e-46 159.0 0.0 1.9e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM85666.1 - 0.00015 20.7 0.0 0.00035 19.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIM85666.1 - 0.0003 20.2 0.0 0.00072 19.0 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EIM85666.1 - 0.0057 16.6 0.0 1.4 8.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EIM85667.1 - 4.6e-06 26.9 1.9 4.7e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EIM85667.1 - 4.3e-05 23.3 0.0 8.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM85667.1 - 0.00012 22.3 1.4 0.00027 21.2 1.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EIM85667.1 - 0.00014 21.7 1.9 0.00058 19.7 0.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM85667.1 - 0.00078 19.4 0.4 0.0022 18.0 0.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EIM85667.1 - 0.001 18.9 0.5 0.001 18.9 0.5 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EIM85667.1 - 0.0012 18.8 1.2 0.0037 17.2 1.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM85667.1 - 0.0042 16.9 0.7 0.0042 16.9 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIM85667.1 - 0.0045 16.8 2.1 0.0064 16.3 0.3 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EIM85667.1 - 0.078 13.0 3.2 0.91 9.6 3.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EIM85667.1 - 0.11 12.6 1.1 0.11 12.6 1.1 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING tRNA-synt_2c PF01411.19 EIM85668.1 - 1.2e-05 24.1 0.0 1.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EIM85668.1 - 0.013 15.6 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Dynactin PF12455.8 EIM85668.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Dynein associated protein MFS_1 PF07690.16 EIM85669.1 - 3.1e-36 125.1 25.3 3.1e-36 125.1 25.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4079 PF13301.6 EIM85669.1 - 0.051 13.7 0.3 0.051 13.7 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Polysacc_deac_1 PF01522.21 EIM85670.1 - 2.3e-21 76.0 0.0 4.9e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1180 PF06679.12 EIM85670.1 - 5 7.5 5.6 5.4 7.4 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Polysacc_deac_1 PF01522.21 EIM85671.1 - 1.6e-20 73.2 0.0 4.1e-19 68.7 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide deacetylase DIOX_N PF14226.6 EIM85672.1 - 1.2e-25 90.6 0.1 1.9e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM85672.1 - 8.1e-16 58.4 0.0 1.7e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polysacc_deac_1 PF01522.21 EIM85673.1 - 2.4e-20 72.7 0.0 4.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase BTB PF00651.31 EIM85674.1 - 0.029 14.6 0.2 0.069 13.4 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain Amino_oxidase PF01593.24 EIM85676.1 - 1.1e-23 84.3 0.2 5.1e-23 82.1 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIM85676.1 - 5.1e-14 52.2 0.0 1.1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM85676.1 - 4.2e-11 42.6 0.0 3.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM85676.1 - 1.1e-08 35.0 0.4 1.6e-07 31.2 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM85676.1 - 2.4e-07 30.2 3.8 5.4e-06 25.7 2.9 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIM85676.1 - 5.1e-06 25.5 0.5 0.0042 15.9 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 EIM85676.1 - 6.6e-06 25.6 0.4 4.8e-05 22.8 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EIM85676.1 - 0.00012 21.5 1.8 0.0002 20.8 1.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM85676.1 - 0.00036 19.7 1.8 0.00039 19.6 0.6 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.16 EIM85676.1 - 0.00088 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EIM85676.1 - 0.0015 18.5 0.7 0.0047 16.9 0.2 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 EIM85676.1 - 0.0023 17.1 1.8 0.0023 17.1 1.8 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EIM85676.1 - 0.0027 17.0 0.2 0.0046 16.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EIM85676.1 - 0.003 18.1 3.5 0.0051 17.4 1.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM85676.1 - 0.0034 16.3 2.0 0.057 12.3 1.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EIM85676.1 - 0.0043 16.4 0.6 0.0069 15.7 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EIM85676.1 - 0.0078 16.1 0.9 0.014 15.3 0.9 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EIM85676.1 - 0.015 15.5 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 EIM85676.1 - 0.019 15.5 0.2 0.54 10.9 0.2 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EIM85676.1 - 0.072 12.4 1.8 0.11 11.8 1.8 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EIM85676.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EIM85676.1 - 0.12 11.9 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 EIM85676.1 - 0.14 12.6 0.0 0.53 10.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Rossmann-like PF10727.9 EIM85676.1 - 0.22 11.4 0.8 0.49 10.3 0.8 1.5 1 0 0 1 1 1 0 Rossmann-like domain GMC_oxred_N PF00732.19 EIM85676.1 - 0.34 10.2 0.6 5.1 6.4 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase SQS_PSY PF00494.19 EIM85677.1 - 9.7e-54 182.6 0.0 1.4e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.15 EIM85678.1 - 9.3e-106 354.8 0.0 1.2e-105 354.5 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Na_H_Exchanger PF00999.21 EIM85679.1 - 4.2e-40 137.7 48.1 6e-40 137.2 48.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G10 PF01125.17 EIM85680.1 - 1.6e-68 229.1 6.0 1.8e-68 228.9 6.0 1.0 1 0 0 1 1 1 1 G10 protein TB2_DP1_HVA22 PF03134.19 EIM85681.1 - 1.3e-13 50.6 2.9 1.6e-13 50.4 0.2 2.3 2 1 1 3 3 3 1 TB2/DP1, HVA22 family AA_permease_2 PF13520.6 EIM85682.1 - 1.7e-53 182.0 54.9 2.1e-53 181.7 54.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM85682.1 - 3.1e-14 52.5 49.6 6.1e-14 51.5 49.5 1.5 1 1 0 1 1 1 1 Amino acid permease Patatin PF01734.22 EIM85682.1 - 0.016 15.4 0.3 0.03 14.5 0.3 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase TMEM126 PF07114.11 EIM85682.1 - 0.02 14.3 1.5 0.054 12.9 0.3 2.3 2 0 0 2 2 2 0 Transmembrane protein 126 Polysacc_deac_1 PF01522.21 EIM85683.1 - 1.4e-14 54.1 0.0 2.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EIM85683.1 - 3.4e-06 26.9 1.0 8.3e-06 25.6 0.3 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 EIM85683.1 - 0.015 13.7 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) NUDIX PF00293.28 EIM85683.1 - 0.15 12.1 0.2 15 5.7 0.1 2.3 2 0 0 2 2 2 0 NUDIX domain GCP_N_terminal PF17681.1 EIM85684.1 - 4.9e-37 128.2 1.3 6.3e-36 124.6 0.1 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EIM85684.1 - 8.8e-24 84.5 5.7 8.8e-24 84.5 5.7 2.7 3 1 0 3 3 3 1 Gamma tubulin complex component C-terminal VWA PF00092.28 EIM85685.1 - 5.5e-06 26.7 0.0 9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EIM85685.1 - 0.00011 22.8 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EIM85685.1 - 0.00035 20.8 0.2 0.00059 20.0 0.2 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EIM85685.1 - 0.011 15.7 0.1 0.029 14.3 0.1 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 EIM85686.1 - 3.3e-05 24.2 0.0 0.00034 20.9 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EIM85686.1 - 0.00038 21.1 0.0 0.00091 19.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EIM85686.1 - 0.00047 20.3 0.0 0.00081 19.5 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Nucleic_acid_bd PF13820.6 EIM85686.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative nucleic acid-binding region VWA_CoxE PF05762.14 EIM85686.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein PCI PF01399.27 EIM85687.1 - 1.6e-14 54.3 0.0 3.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain Thioredoxin_4 PF13462.6 EIM85688.1 - 7.3e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EIM85688.1 - 0.01 15.7 0.0 0.071 12.9 0.0 2.2 1 1 1 3 3 3 0 DSBA-like thioredoxin domain PP1_bind PF15276.6 EIM85689.1 - 0.022 15.1 0.1 0.075 13.3 0.1 1.9 1 0 0 1 1 1 0 Protein phosphatase 1 binding YjcB PF15940.5 EIM85689.1 - 0.085 13.0 0.6 0.19 11.9 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function Desmo_N PF06771.11 EIM85689.1 - 0.13 12.6 0.9 4.7 7.6 0.1 2.6 2 1 0 2 2 2 0 Viral Desmoplakin N-terminus Exonuc_VII_L PF02601.15 EIM85690.1 - 0.099 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GatB_N PF02934.15 EIM85691.1 - 1.6e-103 345.9 0.0 2e-103 345.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EIM85691.1 - 1.8e-29 102.6 0.0 2.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 GatB domain Beta_helix PF13229.6 EIM85693.1 - 7.9e-10 38.8 21.2 1.6e-09 37.8 18.8 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EIM85693.1 - 0.0013 18.1 11.1 0.39 9.9 10.2 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF4690 PF15756.5 EIM85693.1 - 0.023 15.3 0.0 0.052 14.2 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage VSP PF03302.13 EIM85693.1 - 1.6 7.5 9.7 0.57 9.0 0.5 2.6 3 0 0 3 3 3 0 Giardia variant-specific surface protein PAP_central PF04928.17 EIM85694.1 - 6.1e-111 369.3 0.0 7.9e-111 369.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EIM85694.1 - 7.8e-56 188.4 0.0 1.3e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EIM85694.1 - 4.9e-11 42.8 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EIM85694.1 - 0.031 14.0 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain RRM_1 PF00076.22 EIM85695.1 - 1.2e-17 63.4 0.0 2.1e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM85695.1 - 1.6e-06 28.1 0.0 3.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EIM85695.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-3_zeta PF05091.12 EIM85696.1 - 2.7e-207 689.9 0.0 3.1e-207 689.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EIM85696.1 - 0.086 12.3 0.0 4.1 6.9 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus ApbA_C PF08546.11 EIM85697.1 - 2.8e-26 92.2 0.0 4.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EIM85697.1 - 4.9e-19 68.5 0.0 6.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EIM85697.1 - 0.0082 16.4 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 EIM85697.1 - 0.056 13.0 1.1 0.099 12.2 0.3 1.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase ThiF PF00899.21 EIM85697.1 - 0.082 12.3 0.6 0.71 9.2 0.2 2.1 2 1 0 2 2 2 0 ThiF family DM4_12 PF07841.13 EIM85698.1 - 0.018 15.7 0.1 0.038 14.7 0.1 1.5 1 0 0 1 1 1 0 DM4/DM12 family SnoaL PF07366.12 EIM85698.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase GATA PF00320.27 EIM85699.1 - 6.1e-07 28.9 3.4 1.4e-06 27.8 3.4 1.7 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 EIM85699.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf TRP PF06011.12 EIM85701.1 - 6.8e-32 110.7 14.8 6.8e-32 110.7 14.8 2.1 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 EIM85701.1 - 0.015 15.7 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 ML domain CNH PF00780.22 EIM85702.1 - 0.019 14.6 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 CNH domain Ribosomal_S14 PF00253.21 EIM85703.1 - 0.2 11.5 2.0 0.41 10.5 2.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e Alpha_kinase PF02816.18 EIM85704.1 - 6.2e-05 23.2 0.1 7.9e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family NOA36 PF06524.12 EIM85704.1 - 0.44 9.8 4.2 0.39 10.0 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EIM85705.1 - 0 1013.4 25.1 0 1013.2 25.1 1.1 1 0 0 1 1 1 1 Nop14-like family Iso_dh PF00180.20 EIM85706.1 - 4.4e-124 414.1 0.0 5.1e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NOB1_Zn_bind PF08772.11 EIM85707.1 - 3.2e-29 100.9 0.8 5.4e-29 100.1 0.8 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EIM85707.1 - 3.3e-28 98.0 0.2 8.2e-28 96.8 0.2 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease DUF4551 PF15087.6 EIM85707.1 - 0.0023 16.8 3.0 0.0037 16.2 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) zf-NADH-PPase PF09297.11 EIM85707.1 - 0.18 11.5 4.6 0.43 10.3 0.2 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 EIM85707.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 Nudix N-terminal DUF2981 PF11200.8 EIM85707.1 - 3.5 7.3 4.4 5.4 6.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) P21-Arc PF04062.14 EIM85708.1 - 2.6e-59 200.2 0.0 2.8e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Ion_trans PF00520.31 EIM85709.1 - 0.012 14.8 15.5 0.078 12.2 15.5 2.1 1 1 0 1 1 1 0 Ion transport protein Sld5 PF05916.11 EIM85710.1 - 6.3e-22 78.1 0.1 1e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein Haspin_kinase PF12330.8 EIM85711.1 - 6.3e-56 189.9 0.0 9.8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PP2C PF00481.21 EIM85713.1 - 5e-26 91.9 0.0 1.5e-23 83.8 0.0 2.9 1 1 0 2 2 2 2 Protein phosphatase 2C UCH PF00443.29 EIM85714.1 - 3.6e-47 161.0 0.0 5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM85714.1 - 1.1e-20 74.5 0.0 2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EIM85714.1 - 0.082 12.4 0.3 0.61 9.5 0.8 2.1 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2175 PF09943.9 EIM85714.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2 PF00096.26 EIM85715.1 - 4.1e-12 45.8 24.7 0.00022 21.5 0.7 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM85715.1 - 4.9e-06 26.7 25.4 0.0051 17.2 0.1 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM85715.1 - 0.00013 22.5 23.1 0.83 10.7 0.6 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM85715.1 - 0.0003 21.0 5.1 0.13 12.6 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM85715.1 - 0.0003 21.0 6.2 0.099 13.1 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 EIM85715.1 - 0.004 17.4 6.2 0.21 11.9 0.2 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.6 EIM85715.1 - 0.027 14.7 6.7 2.2 8.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Zn_ribbon_SprT PF17283.2 EIM85715.1 - 0.035 14.0 0.2 0.035 14.0 0.2 2.8 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 EIM85715.1 - 0.042 13.9 0.2 0.042 13.9 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIM85715.1 - 0.054 13.3 3.9 1.1 9.1 0.0 3.2 3 0 0 3 3 2 0 zinc-finger C2H2-type DUF3268 PF11672.8 EIM85715.1 - 0.066 13.5 1.4 1.5 9.1 0.2 2.3 1 1 1 2 2 2 0 zinc-finger-containing domain DUF2225 PF09986.9 EIM85715.1 - 0.087 12.5 0.2 0.76 9.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 EIM85715.1 - 0.27 12.0 3.1 1.2 9.9 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbon family zf_UBZ PF18439.1 EIM85715.1 - 0.36 10.5 3.4 14 5.4 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 EIM85715.1 - 0.43 10.8 6.9 1.2 9.4 1.3 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Ribosomal_L37ae PF01780.19 EIM85715.1 - 0.79 9.8 6.6 9.7 6.4 1.7 2.7 1 1 1 2 2 2 0 Ribosomal L37ae protein family Macoilin PF09726.9 EIM85715.1 - 1.6 7.2 4.9 2 6.8 4.9 1.1 1 0 0 1 1 1 0 Macoilin family DZR PF12773.7 EIM85715.1 - 2.9 8.0 6.4 58 3.8 6.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EIM85715.1 - 6.8 6.9 7.8 22 5.3 0.3 3.5 4 0 0 4 4 4 0 Zinc ribbon domain F-box PF00646.33 EIM85716.1 - 1.1e-05 25.1 0.9 8.8e-05 22.3 0.3 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EIM85716.1 - 0.0066 16.3 0.3 0.0066 16.3 0.3 2.0 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 EIM85716.1 - 0.0081 16.0 0.4 0.017 15.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like MIP PF00230.20 EIM85717.1 - 9.3e-24 84.4 8.2 1.1e-23 84.1 8.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Metallophos PF00149.28 EIM85718.1 - 2.3e-35 123.0 0.0 5.6e-35 121.7 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Fer4 PF00037.27 EIM85719.1 - 6.6e-14 51.1 17.5 2e-08 33.7 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EIM85719.1 - 1e-12 48.4 9.3 1.6e-12 47.8 9.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EIM85719.1 - 1.5e-10 41.8 9.5 2.4e-05 25.2 1.1 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EIM85719.1 - 2.2e-09 37.3 6.5 0.00023 21.2 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EIM85719.1 - 3.6e-09 36.6 21.2 2.6e-06 27.5 12.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EIM85719.1 - 1.9e-08 34.3 9.7 3.2e-08 33.6 9.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EIM85719.1 - 2.1e-08 34.5 3.8 0.00019 21.8 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EIM85719.1 - 5.1e-07 29.5 17.8 0.00044 20.2 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EIM85719.1 - 1.4e-06 28.0 11.7 0.0026 17.8 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EIM85719.1 - 7.8e-06 26.0 11.0 0.00036 20.8 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EIM85719.1 - 0.00017 22.1 11.3 0.012 16.2 12.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 EIM85719.1 - 0.00051 20.5 9.9 0.098 13.2 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 EIM85719.1 - 0.01 16.1 5.2 0.74 10.1 0.4 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EIM85719.1 - 0.089 13.0 9.5 0.85 9.8 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EIM85719.1 - 0.27 12.3 16.3 0.39 11.8 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EIM85719.1 - 0.55 11.1 11.9 1.5 9.7 1.3 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain EPF PF17181.4 EIM85719.1 - 0.67 10.0 6.1 0.49 10.4 0.5 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins ETF_QO PF05187.13 EIM85719.1 - 1.5 9.0 7.2 3.8 7.7 0.9 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Prefoldin_2 PF01920.20 EIM85720.1 - 1.4e-23 82.8 1.4 1.7e-23 82.6 1.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit LXG PF04740.12 EIM85720.1 - 0.0039 16.9 1.8 0.012 15.3 0.4 2.0 2 0 0 2 2 2 1 LXG domain of WXG superfamily Phage_Mu_Gam PF07352.12 EIM85720.1 - 0.015 15.2 1.3 0.02 14.8 1.3 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein STAT_alpha PF01017.20 EIM85720.1 - 0.039 13.8 1.8 0.064 13.2 1.8 1.4 1 1 0 1 1 1 0 STAT protein, all-alpha domain Cep57_MT_bd PF06657.13 EIM85720.1 - 0.046 14.2 2.8 1.8 9.1 0.1 2.5 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4924 PF16271.5 EIM85720.1 - 0.052 13.6 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) XhlA PF10779.9 EIM85720.1 - 0.053 13.7 0.7 0.053 13.7 0.7 1.7 2 0 0 2 2 2 0 Haemolysin XhlA ALIX_LYPXL_bnd PF13949.6 EIM85720.1 - 0.07 12.4 2.7 2.5 7.3 0.0 2.1 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV PI3K_P85_iSH2 PF16454.5 EIM85720.1 - 0.077 12.6 3.6 2.7 7.5 0.9 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain WXG100 PF06013.12 EIM85720.1 - 0.1 12.9 0.9 0.97 9.7 0.4 2.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG ArsR PF09824.9 EIM85720.1 - 0.11 12.1 0.1 2.1 7.9 0.0 2.0 2 0 0 2 2 2 0 ArsR transcriptional regulator Laminin_II PF06009.12 EIM85720.1 - 0.17 11.9 1.8 0.67 10.0 0.3 2.0 2 0 0 2 2 2 0 Laminin Domain II DUF2316 PF10078.9 EIM85720.1 - 0.22 11.8 1.5 0.61 10.4 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) OmpH PF03938.14 EIM85720.1 - 0.26 11.6 5.9 1.5 9.1 1.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Tho2 PF11262.8 EIM85720.1 - 0.27 10.4 1.8 2.3 7.3 0.5 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Prefoldin PF02996.17 EIM85720.1 - 0.34 10.8 3.4 4.7 7.2 3.3 2.0 1 1 0 1 1 1 0 Prefoldin subunit Mito_carr PF00153.27 EIM85721.1 - 4.4e-56 186.8 3.0 1.5e-18 66.5 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIM85721.1 - 0.0049 16.1 0.9 0.26 10.4 0.1 2.5 3 0 0 3 3 3 2 Gammaproteobacterial serine protease BCHF PF07284.11 EIM85722.1 - 5.9 6.9 10.7 0.4 10.7 1.8 2.7 1 1 2 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) GRIM-19 PF06212.12 EIM85724.1 - 1.6e-29 102.5 0.1 1.9e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein HMG_box PF00505.19 EIM85725.1 - 4.8e-13 49.3 17.6 6.7e-07 29.6 5.0 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM85725.1 - 2.2e-12 47.4 13.9 2.4e-06 28.1 5.0 2.6 2 1 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 EIM85725.1 - 0.029 14.6 0.9 0.059 13.6 0.9 1.6 1 0 0 1 1 1 0 Protamine and protamine like Acetyltransf_10 PF13673.7 EIM85726.1 - 2.4e-13 50.1 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM85726.1 - 3.2e-07 30.7 0.0 4.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EIM85726.1 - 2.4e-06 28.2 0.0 0.00042 21.0 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM85726.1 - 2.5e-06 27.7 0.0 3.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF5313 PF17240.2 EIM85726.1 - 0.006 17.0 0.0 0.0093 16.4 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5313) FR47 PF08445.10 EIM85726.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PPR_2 PF13041.6 EIM85727.1 - 1e-34 118.5 0.6 1.6e-07 31.4 0.0 11.3 9 3 5 14 14 14 6 PPR repeat family PPR_3 PF13812.6 EIM85727.1 - 2.3e-34 117.2 0.0 2.2e-07 30.8 0.0 8.5 7 2 2 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.20 EIM85727.1 - 3e-32 108.6 3.2 0.00073 19.6 0.3 14.2 16 1 0 16 16 16 6 PPR repeat PPR_1 PF12854.7 EIM85727.1 - 4e-16 58.4 0.1 0.00074 19.2 0.0 8.4 9 0 0 9 9 9 5 PPR repeat PPR_long PF17177.4 EIM85727.1 - 1.9e-12 47.0 2.8 0.0034 16.8 0.1 5.0 2 1 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EIM85727.1 - 3.3e-06 27.5 6.6 20 6.3 0.0 8.7 9 2 1 10 10 10 1 Tetratricopeptide repeat DUF3368 PF11848.8 EIM85727.1 - 0.0018 18.0 0.0 0.023 14.4 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) BTAD PF03704.17 EIM85727.1 - 0.07 13.6 2.7 0.7 10.3 0.3 3.5 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Velvet PF11754.8 EIM85728.1 - 2.3e-75 253.8 8.8 3.8e-72 243.2 8.8 2.6 1 1 0 1 1 1 1 Velvet factor ArfGap PF01412.18 EIM85729.1 - 5.4e-33 113.6 0.0 8.4e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Dioxygenase_N PF04444.14 EIM85729.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Oxysterol_BP PF01237.18 EIM85730.1 - 4.4e-134 447.0 0.9 1.3e-133 445.4 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 EIM85730.1 - 9.3e-13 48.6 0.0 6.8e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM85730.1 - 1.9e-12 47.2 0.5 5.5e-06 26.6 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 EIM85730.1 - 5.5e-12 46.1 0.0 1.7e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 EIM85730.1 - 2e-11 43.0 0.1 0.02 15.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EIM85730.1 - 2e-08 34.3 0.8 0.0022 18.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EIM85730.1 - 3e-08 34.0 0.4 0.00023 21.7 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_8 PF15409.6 EIM85730.1 - 0.00012 22.3 0.3 0.00012 22.3 0.3 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EIM85730.1 - 0.00041 20.7 0.3 0.00041 20.7 0.3 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Sigma70_ner PF04546.13 EIM85730.1 - 0.095 12.6 3.2 0.2 11.5 3.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Coiled-coil_56 PF09813.9 EIM85731.1 - 1.8e-05 24.7 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 T4_Rnl2_C PF18043.1 EIM85731.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal COX7a PF02238.15 EIM85732.1 - 2.3e-12 47.1 0.5 2.7e-12 46.9 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Form-deh_trans PF09163.11 EIM85732.1 - 0.14 11.9 0.0 21 5.0 0.3 2.1 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Cu-oxidase PF00394.22 EIM85733.1 - 8e-46 156.1 0.0 6.5e-42 143.4 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM85733.1 - 1.2e-36 125.4 6.5 1e-34 119.2 0.1 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM85733.1 - 2e-34 118.1 0.7 3.2e-33 114.3 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase PIF1 PF05970.14 EIM85734.1 - 0.00035 19.8 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase CENP-B_N PF04218.13 EIM85734.1 - 0.024 14.3 0.7 0.59 9.8 0.5 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain SH3_13 PF18335.1 EIM85734.1 - 0.049 13.5 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain HNH_2 PF13391.6 EIM85736.1 - 2.7e-06 27.4 0.0 7.2e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Dioxygenase_C PF00775.21 EIM85737.1 - 0.0005 19.6 0.0 0.00091 18.7 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase AAA_5 PF07728.14 EIM85738.1 - 2e-116 384.2 0.0 4.9e-20 71.9 0.0 10.3 9 1 1 10 10 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EIM85738.1 - 4.7e-51 171.4 2.7 8.7e-17 61.3 0.0 5.9 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 EIM85738.1 - 4.1e-26 91.1 0.0 1.6e-25 89.2 0.0 2.2 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 EIM85738.1 - 1.5e-25 89.5 0.0 2.1e-08 34.1 0.0 8.0 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EIM85738.1 - 1.3e-23 83.8 0.3 0.00021 21.7 0.0 7.4 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM85738.1 - 3e-20 73.3 7.5 0.00029 21.3 0.0 8.5 6 1 0 6 6 6 4 AAA ATPase domain AAA_7 PF12775.7 EIM85738.1 - 3.7e-20 72.2 2.7 2.9e-05 23.7 0.0 6.8 7 0 0 7 7 7 4 P-loop containing dynein motor region AAA_22 PF13401.6 EIM85738.1 - 7.4e-17 61.9 0.5 0.0044 17.3 0.0 8.1 7 0 0 7 7 7 3 AAA domain Dynein_heavy PF03028.15 EIM85738.1 - 3.1e-16 59.6 0.0 0.0062 16.6 0.0 6.3 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 EIM85738.1 - 2.2e-15 56.8 0.0 0.0036 17.0 0.0 5.2 5 0 0 5 5 4 3 Sigma-54 interaction domain AAA_6 PF12774.7 EIM85738.1 - 4.2e-14 52.3 0.0 0.026 13.5 0.0 6.8 8 0 0 8 8 7 4 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 EIM85738.1 - 6.6e-13 49.3 0.1 0.029 14.9 0.0 6.4 5 0 0 5 5 5 1 AAA domain TsaE PF02367.17 EIM85738.1 - 4.2e-11 42.9 0.5 2.2 8.3 0.0 6.1 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EIM85738.1 - 1.2e-10 40.9 1.2 0.0084 15.2 0.0 5.9 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_30 PF13604.6 EIM85738.1 - 3.2e-10 40.0 0.0 0.02 14.6 0.0 6.3 5 0 0 5 5 5 2 AAA domain ABC_tran PF00005.27 EIM85738.1 - 6.1e-10 39.8 0.8 0.99 9.9 0.0 6.3 6 0 0 6 6 5 3 ABC transporter AAA_14 PF13173.6 EIM85738.1 - 5.1e-09 36.2 0.0 0.061 13.4 0.0 6.3 6 0 0 6 6 6 1 AAA domain Sigma54_activ_2 PF14532.6 EIM85738.1 - 3.3e-08 33.7 0.1 0.013 15.6 0.0 4.8 5 0 0 5 5 4 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 EIM85738.1 - 5.7e-08 32.4 0.4 9.2 5.6 0.0 7.9 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EIM85738.1 - 3.1e-07 30.0 4.4 3.8 7.3 0.1 6.2 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_8 PF12780.7 EIM85738.1 - 1.3e-06 28.0 0.3 0.059 12.7 0.0 5.1 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 RNA_helicase PF00910.22 EIM85738.1 - 3e-06 27.6 0.7 29 5.1 0.0 6.2 7 0 0 7 7 5 0 RNA helicase AAA_28 PF13521.6 EIM85738.1 - 3.9e-06 27.2 5.7 1.5 9.0 0.0 6.1 6 0 0 6 6 5 2 AAA domain RuvB_N PF05496.12 EIM85738.1 - 9.5e-06 25.4 0.4 5.4 6.7 0.0 5.7 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EIM85738.1 - 1.2e-05 25.5 0.0 14 5.8 0.0 5.8 5 0 0 5 5 5 0 AAA domain DUF815 PF05673.13 EIM85738.1 - 1.5e-05 24.3 0.0 6.1 5.9 0.0 4.6 5 0 0 5 5 4 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EIM85738.1 - 1.6e-05 24.3 0.0 2.4 7.4 0.0 5.4 5 0 0 5 5 5 1 Zeta toxin NACHT PF05729.12 EIM85738.1 - 2.4e-05 24.3 0.2 4.5 7.2 0.0 4.8 4 0 0 4 4 4 0 NACHT domain AAA_19 PF13245.6 EIM85738.1 - 3.7e-05 24.1 4.8 0.63 10.4 0.1 5.2 5 0 0 5 5 3 1 AAA domain SRP54 PF00448.22 EIM85738.1 - 0.00012 21.8 0.0 22 4.6 0.0 4.7 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EIM85738.1 - 0.00017 21.5 0.3 14 5.5 0.1 5.5 5 0 0 5 5 5 0 NTPase Roc PF08477.13 EIM85738.1 - 0.00062 20.0 0.7 13 6.1 0.0 4.7 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EIM85738.1 - 0.0011 18.7 0.0 2.9 7.6 0.0 4.3 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EIM85738.1 - 0.0018 18.2 0.2 6.6 6.6 0.0 4.4 4 0 0 4 4 4 0 RsgA GTPase AAA_23 PF13476.6 EIM85738.1 - 0.0022 18.5 1.3 63 4.0 0.0 5.4 5 0 0 5 5 5 0 AAA domain AAA_24 PF13479.6 EIM85738.1 - 0.0026 17.5 0.2 9.7 5.9 0.0 4.6 5 0 0 5 5 4 0 AAA domain AAA_11 PF13086.6 EIM85738.1 - 0.0075 16.1 0.0 18 5.0 0.0 4.5 4 0 0 4 4 3 0 AAA domain CPT PF07931.12 EIM85738.1 - 0.0079 16.1 1.4 18 5.1 0.1 5.3 6 0 0 6 6 5 0 Chloramphenicol phosphotransferase-like protein DEAD PF00270.29 EIM85738.1 - 0.012 15.4 0.4 11 5.7 0.0 3.7 4 0 0 4 4 3 0 DEAD/DEAH box helicase VWA PF00092.28 EIM85738.1 - 0.014 15.6 0.2 0.032 14.5 0.2 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain IstB_IS21 PF01695.17 EIM85738.1 - 0.021 14.6 0.0 19 5.0 0.0 4.3 5 0 0 5 5 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EIM85738.1 - 0.024 14.7 3.1 21 5.2 0.0 5.0 6 0 0 6 6 4 0 50S ribosome-binding GTPase ResIII PF04851.15 EIM85738.1 - 0.025 14.6 0.0 19 5.2 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TniB PF05621.11 EIM85738.1 - 0.028 13.9 0.1 6.2 6.2 0.0 3.9 4 0 0 4 4 4 0 Bacterial TniB protein AAA_25 PF13481.6 EIM85738.1 - 0.028 14.0 13.2 2.5 7.6 0.3 6.5 7 0 0 7 7 5 0 AAA domain dNK PF01712.19 EIM85738.1 - 0.037 13.9 2.7 12 5.7 0.0 4.1 5 0 0 5 5 4 0 Deoxynucleoside kinase CbiA PF01656.23 EIM85738.1 - 0.043 13.9 0.1 5.6 7.0 0.0 3.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EIM85738.1 - 0.13 11.8 2.0 98 2.5 0.0 5.0 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EIM85738.1 - 0.17 11.8 0.6 33 4.3 0.0 4.1 5 0 0 5 5 4 0 Rad17 P-loop domain Aminotran_1_2 PF00155.21 EIM85740.1 - 1.3e-22 80.5 0.0 1.6e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EIM85740.1 - 3.1e-13 49.3 0.0 3.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase RicinB_lectin_2 PF14200.6 EIM85741.1 - 1.2e-15 58.0 0.0 2.9e-07 31.1 0.0 4.3 3 1 2 5 5 5 4 Ricin-type beta-trefoil lectin domain-like Ribosomal_L35p PF01632.19 EIM85742.1 - 1.6e-16 60.5 4.6 2.1e-16 60.1 4.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 Ufd2P_core PF10408.9 EIM85743.1 - 1.1e-212 708.0 1.1 1.4e-212 707.8 1.1 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EIM85743.1 - 4.2e-28 97.3 1.0 2.3e-27 95.0 0.6 2.4 2 0 0 2 2 2 1 U-box domain DUF2999 PF11212.8 EIM85743.1 - 0.18 12.1 0.3 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) Eaf7 PF07904.13 EIM85744.1 - 1.9e-19 70.0 0.2 5.3e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 RasGEF PF00617.19 EIM85745.1 - 4.9e-21 75.7 2.0 4.9e-21 75.7 2.0 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EIM85745.1 - 3.6e-07 30.4 0.2 8.8e-07 29.1 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 EIM85746.1 - 1.3e-18 67.8 0.0 2.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EIM85746.1 - 5.5e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif AMPK1_CBM PF16561.5 EIM85748.1 - 1.1e-22 80.1 0.0 2.1e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EIM85748.1 - 5.4e-19 68.2 0.7 5.2e-14 52.3 0.0 3.3 2 0 0 2 2 2 2 5'-AMP-activated protein kinase beta subunit, interaction domain MAGE_N PF12440.8 EIM85748.1 - 0.14 12.8 0.2 0.14 12.8 0.2 5.4 5 1 1 6 6 6 0 Melanoma associated antigen family N terminal DEAD PF00270.29 EIM85750.1 - 1.3e-19 70.6 0.0 2.6e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM85750.1 - 6.4e-15 55.5 0.0 9.6e-13 48.5 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EIM85750.1 - 7.9e-10 39.3 0.1 2.8e-09 37.6 0.1 2.1 1 0 0 1 1 1 1 RecQ zinc-binding T4SS-DNA_transf PF02534.14 EIM85750.1 - 0.053 12.3 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Filaggrin PF03516.13 EIM85750.1 - 0.97 10.2 8.1 4.1 8.2 3.8 3.1 2 0 0 2 2 2 0 Filaggrin Aldolase_II PF00596.21 EIM85751.1 - 7.3e-39 133.6 0.0 8.6e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PAS_3 PF08447.12 EIM85752.1 - 4.3e-09 36.6 0.0 1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EIM85752.1 - 0.00019 21.5 0.0 0.0093 16.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EIM85752.1 - 0.00058 19.8 0.0 0.0032 17.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EIM85752.1 - 0.0077 16.5 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 1 PAS domain BHD_3 PF10405.9 EIM85753.1 - 7.9e-29 99.9 0.0 1.6e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EIM85753.1 - 4.5e-25 88.1 0.0 1.3e-24 86.5 0.0 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 EIM85753.1 - 1.5e-18 67.5 2.3 1.5e-18 67.5 2.3 4.1 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 EIM85753.1 - 5.4e-18 64.6 0.0 1e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 EIM85753.1 - 1.5e-06 28.6 0.0 1.4e-05 25.5 0.0 2.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily Tli4_C PF18426.1 EIM85753.1 - 0.0014 18.9 0.5 1.3 9.3 0.0 2.7 2 0 0 2 2 2 2 Tle cognate immunity protein 4 C-terminal domain HAD_2 PF13419.6 EIM85754.1 - 5.4e-16 59.2 0.0 7.9e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM85754.1 - 3.5e-11 43.8 0.0 1.8e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM85754.1 - 1.4e-05 25.1 0.0 3.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Ribul_P_3_epim PF00834.19 EIM85754.1 - 0.031 13.7 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family BTB PF00651.31 EIM85755.1 - 1.7e-06 28.2 0.0 6.6e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain WD40 PF00400.32 EIM85756.1 - 2.6e-24 85.0 0.3 9e-06 26.3 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM85756.1 - 2.6e-09 37.2 0.1 0.03 14.6 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM85756.1 - 5.7e-05 22.0 0.2 0.002 16.8 0.1 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EIM85756.1 - 0.00098 18.8 0.1 0.0023 17.6 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.5 EIM85756.1 - 0.0011 18.1 0.7 1.3 7.9 0.2 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM85756.1 - 0.017 14.4 0.1 0.41 9.9 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain CTC1_2 PF15491.6 EIM85756.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Fungal_trans PF04082.18 EIM85757.1 - 1.1e-19 70.5 0.1 5.5e-19 68.2 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM85757.1 - 7.1e-08 32.4 11.3 1.3e-07 31.7 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EIM85757.1 - 0.0094 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Urease_linker PF18473.1 EIM85757.1 - 0.2 11.6 0.3 0.43 10.5 0.3 1.5 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain NAD_binding_10 PF13460.6 EIM85758.1 - 2.9e-13 50.1 0.0 4.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM85758.1 - 8.4e-12 45.1 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EIM85758.1 - 5.4e-11 42.4 0.0 6.9e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM85758.1 - 3.2e-10 39.5 0.0 1.5e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EIM85758.1 - 9.3e-10 38.1 0.0 2e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EIM85758.1 - 8.2e-07 28.5 0.1 0.0063 15.7 0.0 3.3 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 EIM85758.1 - 0.0003 20.3 0.0 0.0011 18.4 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EIM85758.1 - 0.00041 19.9 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EIM85758.1 - 0.0044 16.6 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM85758.1 - 0.0045 16.9 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EIM85758.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 EIM85758.1 - 0.22 11.6 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2462 PF09495.10 EIM85759.1 - 7.2e-22 77.9 16.3 7.9e-22 77.8 16.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Ribonuclease PF00545.20 EIM85760.1 - 2.8e-07 31.2 0.0 3.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ribonuclease HTH_Tnp_Tc5 PF03221.16 EIM85761.1 - 1.2e-08 34.9 0.3 2.5e-08 33.8 0.3 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EIM85761.1 - 6.3e-05 22.5 0.1 0.00014 21.4 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EIM85761.1 - 0.0015 18.3 0.2 0.0032 17.2 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EIM85761.1 - 0.0017 18.1 0.1 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 EIM85761.1 - 0.0027 17.5 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_3 PF01381.22 EIM85761.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_Crp_2 PF13545.6 EIM85761.1 - 0.0067 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.6 EIM85761.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.16 EIM85761.1 - 0.019 14.5 0.2 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 EIM85761.1 - 0.026 14.1 0.0 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 EIM85761.1 - 0.028 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 EIM85761.1 - 0.032 14.0 0.1 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_31 PF13560.6 EIM85761.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 EIM85761.1 - 0.051 13.5 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.21 EIM85761.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_37 PF13744.6 EIM85761.1 - 0.15 12.0 0.0 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.16 EIM85762.1 - 3e-12 46.2 47.1 3e-12 46.2 47.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EIM85763.1 - 3.8e-60 203.5 0.0 5.9e-60 202.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85763.1 - 6.1e-31 107.6 0.0 1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM85763.1 - 0.025 13.9 0.0 0.068 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF2235 PF09994.9 EIM85764.1 - 2.5e-85 286.3 0.0 3.4e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 EIM85764.1 - 0.09 12.7 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EIM85764.1 - 0.3 11.7 4.0 12 6.4 0.1 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family DPBB_1 PF03330.18 EIM85765.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase SH3_9 PF14604.6 EIM85766.1 - 3.5e-22 78.0 1.1 7.5e-13 48.1 0.2 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EIM85766.1 - 8.6e-20 70.1 1.6 4.5e-09 35.8 0.0 2.7 2 1 0 2 2 2 2 SH3 domain FCH PF00611.23 EIM85766.1 - 8.8e-18 64.4 4.8 3.1e-17 62.6 0.2 3.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 EIM85766.1 - 2.3e-17 62.4 0.1 8.5e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 EIM85766.1 - 2.5e-12 46.5 5.0 4.4e-12 45.7 5.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 EIM85766.1 - 0.00023 21.4 0.8 0.00039 20.6 0.1 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain AA_synth PF06684.11 EIM85766.1 - 0.0057 16.2 0.2 1.2 8.7 0.1 2.9 3 0 0 3 3 3 1 Amino acid synthesis FYVE PF01363.21 EIM85766.1 - 0.061 13.5 2.1 0.15 12.2 2.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF4241 PF14025.6 EIM85766.1 - 0.25 11.6 4.3 5.5 7.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4241) BAR_3 PF16746.5 EIM85766.1 - 1.5 8.4 15.4 0.15 11.7 8.1 2.8 2 1 1 3 3 3 0 BAR domain of APPL family CAF1 PF04857.20 EIM85767.1 - 2e-19 70.0 0.0 5.3e-12 45.6 0.0 2.8 1 1 1 2 2 2 2 CAF1 family ribonuclease MFS_1 PF07690.16 EIM85768.1 - 4e-17 62.2 39.1 4e-17 62.2 39.1 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Ribonuclease PF00545.20 EIM85769.1 - 2.1e-07 31.6 0.0 2.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ribonuclease MARVEL PF01284.23 EIM85770.1 - 7.9e-05 22.7 12.6 0.0019 18.2 12.6 2.0 1 1 0 1 1 1 1 Membrane-associating domain COX2_TM PF02790.15 EIM85770.1 - 0.011 15.9 3.3 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1345 PF07077.11 EIM85770.1 - 0.2 11.3 6.0 0.36 10.5 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Peptidase_U4 PF03419.13 EIM85770.1 - 0.82 8.9 5.7 1.8 7.8 5.7 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA FHA PF00498.26 EIM85771.1 - 4.5e-16 58.9 0.0 7.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EIM85771.1 - 1.9e-06 28.1 0.0 0.0001 22.5 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF1325 PF07039.11 EIM85772.1 - 5.8e-36 123.5 0.1 8.1e-36 123.0 0.1 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 EIM85772.1 - 0.0046 17.4 1.1 0.06 13.8 0.0 2.6 2 1 0 2 2 2 1 Agenet domain EBP PF05241.12 EIM85774.1 - 1.8e-67 226.2 9.5 2.1e-67 226.0 9.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 EIM85774.1 - 0.087 13.2 9.1 0.13 12.7 8.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2781) F-box-like PF12937.7 EIM85775.1 - 6.9e-05 22.7 0.0 0.00026 20.8 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM85775.1 - 0.11 13.0 6.7 5.2 7.6 0.2 4.1 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EIM85778.1 - 1.2e-07 31.5 0.0 3.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like FYRC PF05965.14 EIM85780.1 - 3.3e-16 59.2 0.0 5.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 EIM85780.1 - 1.2e-14 53.9 0.4 1.8e-14 53.3 0.4 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus p450 PF00067.22 EIM85782.1 - 7.5e-57 193.1 0.0 2.8e-50 171.4 0.0 4.0 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EIM85783.1 - 7.2e-57 193.1 0.0 1.1e-56 192.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 EIM85784.1 - 1e-82 277.0 0.0 1.3e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase KASH_CCD PF14662.6 EIM85785.1 - 0.00059 19.7 14.8 0.00059 19.7 14.8 2.9 1 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EIM85785.1 - 0.0031 16.4 12.4 0.0031 16.4 12.4 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein IMP_cyclohyd PF07826.11 EIM85785.1 - 0.0057 16.3 0.2 0.0096 15.5 0.2 1.3 1 0 0 1 1 1 1 IMP cyclohydrolase-like protein YabA PF06156.13 EIM85785.1 - 0.017 15.7 18.3 0.035 14.7 3.4 3.7 1 1 2 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 EIM85785.1 - 0.025 14.7 20.5 0.05 13.7 12.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CtsR_C PF17727.1 EIM85785.1 - 0.029 14.5 1.3 0.79 9.9 0.1 2.6 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Na_H_antiporter PF03553.14 EIM85785.1 - 0.058 12.6 0.1 0.087 12.0 0.1 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter family MCD_N PF17408.2 EIM85785.1 - 0.077 13.1 1.1 13 6.0 0.1 2.7 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain ATG16 PF08614.11 EIM85785.1 - 0.38 10.9 25.3 23 5.1 25.2 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 EIM85785.1 - 0.46 11.0 22.5 0.32 11.5 1.8 4.3 1 1 2 4 4 4 0 Cell division protein ZapB BBP1_C PF15272.6 EIM85785.1 - 0.71 9.7 17.1 0.29 10.9 10.0 2.6 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Shugoshin_N PF07558.11 EIM85785.1 - 0.75 9.7 3.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 EIM85785.1 - 0.98 9.3 11.0 0.44 10.4 0.4 4.2 3 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 EIM85785.1 - 1.8 8.7 17.1 5.9 7.1 0.8 4.7 4 1 1 5 5 5 0 bZIP transcription factor DUF1759 PF03564.15 EIM85785.1 - 2.6 8.0 7.7 0.28 11.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) TMF_DNA_bd PF12329.8 EIM85785.1 - 2.8 8.0 17.8 1.9 8.6 1.9 4.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 EIM85785.1 - 2.9 8.4 7.5 2.4 8.6 0.6 3.1 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) UPF0231 PF06062.11 EIM85785.1 - 3.7 7.8 7.8 0.43 10.9 1.1 2.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0231) Phage_GP20 PF06810.11 EIM85785.1 - 7 6.4 18.2 0.058 13.2 5.4 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 HA2 PF04408.23 EIM85786.1 - 5.9e-25 87.6 0.0 5.9e-25 87.6 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIM85786.1 - 3.3e-21 75.4 0.0 1.8e-20 73.1 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIM85786.1 - 5.4e-12 46.0 0.3 1.1e-10 41.8 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM85786.1 - 2e-06 27.7 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIM85786.1 - 4.2e-06 27.1 0.2 7e-05 23.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EIM85786.1 - 0.0028 18.2 7.4 0.083 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EIM85786.1 - 0.014 15.4 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 EIM85786.1 - 0.059 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC eIF3g PF12353.8 EIM85786.1 - 0.48 10.8 5.7 10 6.5 1.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G SEN1_N PF12726.7 EIM85787.1 - 1.2e-153 513.1 0.0 1.7e-153 512.7 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EIM85787.1 - 2.6e-64 217.6 3.4 2.6e-64 217.6 3.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EIM85787.1 - 4.1e-58 196.3 0.0 8e-58 195.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM85787.1 - 6.5e-08 32.5 0.2 5.9e-06 26.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EIM85787.1 - 3.6e-06 27.4 0.3 1.8e-05 25.1 0.3 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EIM85787.1 - 0.0014 18.7 0.0 0.0087 16.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EIM85787.1 - 0.0057 16.5 0.1 4.2 7.2 0.0 2.6 2 0 0 2 2 2 2 Helicase DEAD PF00270.29 EIM85787.1 - 0.032 14.0 0.4 0.11 12.2 0.1 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EIM85787.1 - 0.033 14.5 1.0 0.15 12.4 0.3 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EIM85787.1 - 0.035 14.5 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM85787.1 - 0.12 12.8 0.3 0.66 10.3 0.3 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EIM85787.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EIM85787.1 - 0.22 10.5 1.2 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 EIM85787.1 - 0.31 11.5 8.3 1.3 9.4 8.3 1.9 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EIM85787.1 - 1.1 8.7 13.7 0.78 9.2 0.0 2.9 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain Translin PF01997.16 EIM85788.1 - 1.1e-48 165.9 0.0 1.3e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Translin family Mon1 PF03164.14 EIM85789.1 - 1.2e-115 386.9 0.0 1.3e-115 386.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 BTB PF00651.31 EIM85790.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain tRNA_bind PF01588.20 EIM85792.1 - 2.7e-27 94.7 0.0 4.7e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EIM85792.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM85792.1 - 0.0012 18.9 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM85792.1 - 0.0014 18.8 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNA_polI_A34 PF08208.11 EIM85792.1 - 0.43 10.6 18.9 0.69 10.0 18.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med3 PF11593.8 EIM85792.1 - 6.3 5.9 10.5 9.2 5.3 10.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NARP1 PF12569.8 EIM85792.1 - 6.4 5.6 8.2 9.5 5.0 8.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1180 PF06679.12 EIM85792.1 - 9.6 6.6 7.3 16 5.9 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DIOX_N PF14226.6 EIM85793.1 - 8.9e-25 87.7 0.0 1.5e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM85793.1 - 3e-12 46.9 0.0 7.3e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Herpes_BLLF1 PF05109.13 EIM85796.1 - 0.3 9.0 33.8 0.5 8.3 33.8 1.3 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) CBFD_NFYB_HMF PF00808.23 EIM85797.1 - 1.3e-06 28.6 0.0 2.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Amidohydro_1 PF01979.20 EIM85798.1 - 1.1e-49 169.6 0.0 1.4e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM85798.1 - 2.2e-05 24.1 0.5 0.00048 19.7 0.3 2.3 2 1 0 2 2 2 1 Amidohydrolase family SKN1 PF03935.15 EIM85799.1 - 2.5e-181 603.5 1.8 3.7e-181 602.9 1.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Ribosomal_L6 PF00347.23 EIM85799.1 - 6e-18 65.3 0.0 6.2e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 MRP-L47 PF06984.13 EIM85800.1 - 3.2e-20 72.1 4.9 3.8e-20 71.8 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Complex1_LYR PF05347.15 EIM85801.1 - 1.9e-07 31.0 0.1 2.9e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EIM85801.1 - 0.013 16.2 0.1 0.017 15.9 0.1 1.3 1 1 0 1 1 1 0 Complex1_LYR-like Hamartin PF04388.12 EIM85802.1 - 0.73 8.4 7.8 1.2 7.7 7.8 1.3 1 0 0 1 1 1 0 Hamartin protein F-box-like PF12937.7 EIM85803.1 - 1.9e-11 43.7 11.5 6.4e-05 22.8 2.3 4.2 2 2 0 2 2 2 2 F-box-like F-box PF00646.33 EIM85803.1 - 0.021 14.7 5.6 15 5.6 0.1 4.6 5 0 0 5 5 5 0 F-box domain Pkr1 PF08636.10 EIM85803.1 - 0.089 13.0 0.0 22 5.3 0.0 2.7 2 0 0 2 2 2 0 ER protein Pkr1 DAGK_prokar PF01219.19 EIM85803.1 - 0.14 12.0 0.0 28 4.6 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase MFS_1 PF07690.16 EIM85805.1 - 1.6e-21 76.7 38.2 9.3e-21 74.1 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BatA PF07584.11 EIM85805.1 - 0.06 13.7 2.3 0.081 13.3 0.0 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Vpu PF00558.19 EIM85805.1 - 0.15 11.9 0.3 0.91 9.3 0.0 2.4 3 0 0 3 3 3 0 Vpu protein Phage_holin_3_6 PF07332.11 EIM85805.1 - 6.7 6.8 23.5 3.1 7.9 2.0 3.8 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III vATP-synt_AC39 PF01992.16 EIM85806.1 - 5.5e-117 391.0 0.1 6.2e-117 390.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 EIM85806.1 - 0.18 11.7 0.3 0.6 10.1 0.1 1.9 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain ATP-synt_C PF00137.21 EIM85807.1 - 8.7e-31 106.1 31.5 2.9e-18 66.0 13.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C zf-CCHC_3 PF13917.6 EIM85808.1 - 2.7e-18 65.6 1.2 2.7e-18 65.6 1.2 1.7 2 0 0 2 2 2 1 Zinc knuckle Tmemb_cc2 PF10267.9 EIM85808.1 - 0.74 8.9 9.4 0.8 8.8 9.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Nop14 PF04147.12 EIM85808.1 - 0.93 7.6 16.7 1.1 7.4 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EIM85808.1 - 0.96 7.7 19.1 0.99 7.6 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 EIM85808.1 - 1.2 8.3 8.2 1.5 7.9 8.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RP-C_C PF11800.8 EIM85808.1 - 1.4 9.0 6.7 1.9 8.5 6.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Macoilin PF09726.9 EIM85808.1 - 1.7 7.1 16.9 1.8 7.0 16.9 1.0 1 0 0 1 1 1 0 Macoilin family PPP4R2 PF09184.11 EIM85808.1 - 2.2 7.8 15.7 2.5 7.6 15.7 1.1 1 0 0 1 1 1 0 PPP4R2 Peroxin-3 PF04882.12 EIM85808.1 - 3.2 6.7 11.8 3.3 6.6 11.8 1.2 1 0 0 1 1 1 0 Peroxin-3 Menin PF05053.13 EIM85808.1 - 6.3 5.0 10.0 7.3 4.8 10.0 1.0 1 0 0 1 1 1 0 Menin EHN PF06441.12 EIM85810.1 - 4.6e-34 117.1 1.3 1.8e-32 111.9 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EIM85810.1 - 8.9e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM85810.1 - 0.067 13.8 4.8 0.18 12.4 4.8 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 EIM85811.1 - 8.7e-14 51.6 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM85811.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM85811.1 - 0.018 16.1 0.0 0.039 15.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Receptor_IA-2 PF11548.8 EIM85811.1 - 0.043 13.8 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 F-box-like PF12937.7 EIM85812.1 - 8.4e-09 35.2 0.0 2.1e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 F-box-like Laminin_B PF00052.18 EIM85812.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Laminin B (Domain IV) RNA_pol_3_Rpc31 PF11705.8 EIM85812.1 - 0.3 11.3 31.8 0.14 12.3 8.3 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 EIM85812.1 - 6.6 6.5 10.8 22 4.7 4.9 2.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Homeobox_KN PF05920.11 EIM85813.1 - 2.5e-19 68.9 0.0 4.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EIM85813.1 - 4.1e-05 23.3 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain LRR_4 PF12799.7 EIM85814.1 - 4.1e-27 93.8 34.8 1e-05 25.8 0.6 7.8 5 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM85814.1 - 1.3e-20 72.9 39.4 8.5e-07 28.6 2.4 7.4 5 1 3 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 EIM85814.1 - 1.3e-12 47.6 14.9 0.031 13.8 0.1 5.3 3 1 2 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 EIM85814.1 - 0.24 12.1 36.2 7.3 7.6 0.2 10.7 8 4 1 9 9 9 0 Leucine Rich Repeat Ydc2-catalyt PF09159.10 EIM85815.1 - 0.12 12.1 0.8 0.22 11.2 0.8 1.4 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 RRM_1 PF00076.22 EIM85816.1 - 5.4e-07 29.3 0.0 9.9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIM85816.1 - 1.4e-06 28.3 0.0 3.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 EIM85816.1 - 0.0002 21.3 0.0 0.00047 20.1 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Apo-CII PF05355.11 EIM85816.1 - 0.077 13.2 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Apolipoprotein C-II Mob_Pre PF01076.19 EIM85816.1 - 0.11 12.4 0.1 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Plasmid recombination enzyme MucBP_2 PF17965.1 EIM85816.1 - 0.6 10.7 8.0 0.83 10.3 2.7 2.7 2 1 1 3 3 3 0 Mucin binding domain An_peroxidase PF03098.15 EIM85817.1 - 1.1e-32 113.4 0.0 6.5e-19 67.9 0.0 3.4 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EIM85817.1 - 0.022 13.5 0.0 0.044 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome P450 INCENP_N PF12178.8 EIM85817.1 - 0.044 13.8 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal NAT PF04768.13 EIM85818.1 - 1.9e-46 157.8 0.0 3e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EIM85818.1 - 5.2e-27 94.7 0.0 1.2e-26 93.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EIM85818.1 - 6.4e-26 91.4 0.1 1e-25 90.7 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.18 EIM85818.1 - 1.4e-06 28.5 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain FAD_binding_4 PF01565.23 EIM85819.1 - 8.7e-15 54.7 0.6 2e-14 53.5 0.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM85819.1 - 1.6e-08 34.5 0.0 4.3e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 EIM85820.1 - 5e-36 124.3 93.1 4.9e-23 81.6 42.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85820.1 - 6.9e-05 21.9 42.7 0.0049 15.8 18.5 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EIM85820.1 - 0.61 8.6 40.3 0.94 8.0 21.6 2.7 1 1 1 2 2 2 0 MFS/sugar transport protein EHN PF06441.12 EIM85821.1 - 7.8e-31 106.6 0.2 1.8e-29 102.3 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EIM85821.1 - 4e-13 49.6 0.0 6.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold CG-1 PF03859.16 EIM85821.1 - 0.017 14.9 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 CG-1 domain Abhydrolase_6 PF12697.7 EIM85821.1 - 0.044 14.4 11.6 0.021 15.4 8.5 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L23eN PF03939.13 EIM85822.1 - 1.7e-22 79.4 8.1 1.7e-22 79.4 8.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EIM85822.1 - 4.1e-15 55.9 1.7 4.1e-15 55.9 1.7 2.6 2 2 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 EIM85822.1 - 0.0035 17.6 0.3 0.0047 17.2 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5451) ASL_C PF08328.11 EIM85822.1 - 0.018 15.1 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DUF1180 PF06679.12 EIM85823.1 - 0.025 15.0 0.3 0.025 15.0 0.3 9.1 3 1 2 5 5 5 0 Protein of unknown function (DUF1180) LapA_dom PF06305.11 EIM85823.1 - 0.25 11.2 0.7 22 5.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RPAP3_C PF13877.6 EIM85824.1 - 1.2e-13 51.4 0.0 2.2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 EIM85824.1 - 1.6e-13 49.6 4.2 0.0016 18.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIM85824.1 - 4.4e-13 48.4 2.4 3.9e-06 26.4 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM85824.1 - 2.7e-07 31.0 0.7 5.7e-05 23.6 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM85824.1 - 2.9e-07 30.7 4.7 0.068 14.0 0.4 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM85824.1 - 2.6e-06 27.2 0.6 0.86 10.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM85824.1 - 2.6e-06 27.0 1.0 0.00012 21.7 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EIM85824.1 - 1.4e-05 25.6 5.0 9.2e-05 23.0 0.3 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM85824.1 - 0.00019 21.7 3.7 0.0012 19.1 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EIM85824.1 - 0.00075 19.6 0.7 0.52 10.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIM85824.1 - 0.0033 17.7 0.4 0.047 14.1 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM85824.1 - 0.0042 17.0 0.0 3.4 7.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIM85824.1 - 0.0056 15.9 0.4 1.4 8.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EIM85824.1 - 0.064 13.2 2.4 0.45 10.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 EIM85825.1 - 7.2e-29 101.0 0.0 1.3e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EIM85825.1 - 1e-14 54.6 16.2 2.7e-06 28.0 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 EIM85825.1 - 1.1e-14 54.2 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EIM85825.1 - 0.00042 20.6 0.0 1.5 9.2 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM85825.1 - 0.013 14.2 0.2 0.085 11.5 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Methyltransf_31 PF13847.6 EIM85827.1 - 7.2e-17 61.6 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM85827.1 - 1e-14 55.0 0.2 4.4e-14 52.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM85827.1 - 1.2e-14 54.7 0.1 6.1e-14 52.4 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM85827.1 - 3e-13 50.4 0.0 5.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM85827.1 - 8.2e-13 48.5 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM85827.1 - 6.7e-10 38.7 0.0 1.2e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EIM85827.1 - 1.2e-08 35.0 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 EIM85827.1 - 1.1e-07 31.1 0.0 1.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EIM85827.1 - 0.00011 21.7 0.1 0.00028 20.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Fibrillarin PF01269.17 EIM85827.1 - 0.0035 16.5 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_32 PF13679.6 EIM85827.1 - 0.005 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 EIM85827.1 - 0.0055 15.8 0.0 0.0088 15.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltr_RsmB-F PF01189.17 EIM85827.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TPMT PF05724.11 EIM85827.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 EIM85827.1 - 0.02 14.2 0.0 0.042 13.1 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EIM85827.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 EIM85827.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EIM85827.1 - 0.054 13.1 0.0 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 EIM85827.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CRAL_TRIO PF00650.20 EIM85828.1 - 2.8e-20 72.6 0.0 4.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIM85828.1 - 0.0017 18.5 0.1 0.0041 17.3 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Nipped-B_C PF12830.7 EIM85829.1 - 3.5e-51 173.9 3.1 4.5e-50 170.2 3.7 2.6 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EIM85829.1 - 7.1e-15 55.0 0.4 4.4e-14 52.5 0.2 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EIM85829.1 - 0.00016 21.6 4.3 1.4 9.4 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EIM85829.1 - 0.012 16.0 3.9 0.19 12.1 0.1 4.5 5 1 0 5 5 5 0 HEAT repeats Cnd1 PF12717.7 EIM85829.1 - 0.12 12.5 0.7 0.42 10.6 0.1 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EIM85829.1 - 1 9.9 4.7 19 5.9 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat Cad PF03596.13 EIM85830.1 - 0.06 13.2 7.5 0.93 9.4 0.0 3.1 3 1 0 3 3 3 0 Cadmium resistance transporter Transket_pyr PF02779.24 EIM85831.1 - 1.1e-67 227.2 0.0 1.6e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EIM85831.1 - 7.2e-61 205.7 0.0 1.2e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EIM85831.1 - 6.1e-52 175.4 0.0 1.1e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EIM85831.1 - 1.1e-19 69.8 0.7 1.9e-19 68.9 0.7 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Cep57_MT_bd PF06657.13 EIM85832.1 - 3.9e-22 78.5 0.0 3.9e-22 78.5 0.0 3.3 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EIM85832.1 - 1.3e-08 34.8 5.4 1.3e-08 34.8 5.4 2.6 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 HxlR PF01638.17 EIM85832.1 - 0.022 14.6 2.0 0.066 13.1 0.4 2.4 2 1 0 2 2 2 0 HxlR-like helix-turn-helix IZUMO PF15005.6 EIM85832.1 - 0.24 11.9 2.5 0.55 10.7 2.5 1.6 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated COG5 PF10392.9 EIM85832.1 - 0.32 11.2 6.4 1.8 8.8 3.4 3.1 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 EIM85832.1 - 0.49 9.7 8.1 4.2 6.6 9.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 EIM85832.1 - 2.2 8.7 12.7 3.1 8.2 11.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) RIBIOP_C PF04950.12 EIM85833.1 - 2e-94 316.3 0.0 2e-94 316.3 0.0 1.6 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EIM85833.1 - 3.1e-30 104.1 0.0 7.9e-30 102.8 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 EIM85833.1 - 2.9e-06 27.8 0.1 9e-06 26.2 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM85833.1 - 5.3e-05 23.5 0.0 0.00015 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EIM85833.1 - 8.9e-05 22.1 0.0 0.022 14.3 0.0 2.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIM85833.1 - 0.0005 20.1 0.1 0.002 18.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EIM85833.1 - 0.00093 19.4 0.0 0.0031 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EIM85833.1 - 0.0012 19.2 0.0 0.0026 18.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EIM85833.1 - 0.0031 18.0 0.7 0.0077 16.7 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_18 PF13238.6 EIM85833.1 - 0.0046 17.5 0.7 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EIM85833.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EIM85833.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EIM85833.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EIM85833.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EIM85833.1 - 0.034 13.7 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EIM85833.1 - 0.041 13.8 0.0 0.041 13.8 0.0 2.2 3 0 0 3 3 2 0 RsgA GTPase NTPase_1 PF03266.15 EIM85833.1 - 0.059 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 EIM85833.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 EIM85833.1 - 0.76 9.8 0.0 0.76 9.8 0.0 2.8 4 0 0 4 4 3 0 Helicase HerA, central domain AAA_11 PF13086.6 EIM85833.1 - 2.4 7.9 8.4 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EIM85833.1 - 5.8 5.8 9.5 1.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF4203 PF13886.6 EIM85834.1 - 1.4 8.6 24.5 0.21 11.2 18.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4203) RseC_MucC PF04246.12 EIM85834.1 - 6.9 6.6 8.8 19 5.2 3.3 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC CoA_transf_3 PF02515.17 EIM85835.1 - 6.1e-126 420.5 0.0 6.9e-126 420.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DEAD PF00270.29 EIM85836.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM85836.1 - 0.029 14.4 0.0 0.052 13.6 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RXT2_N PF08595.11 EIM85837.1 - 0.041 13.9 0.2 0.05 13.6 0.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EIM85837.1 - 0.18 10.0 0.7 0.17 10.1 0.7 1.0 1 0 0 1 1 1 0 Nop14-like family hNIFK_binding PF12196.8 EIM85837.1 - 1.6 8.2 0.1 1.6 8.2 0.1 2.6 2 1 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Asp_protease PF09668.10 EIM85839.1 - 0.073 12.9 0.0 0.079 12.8 0.0 1.0 1 0 0 1 1 1 0 Aspartyl protease Rootletin PF15035.6 EIM85842.1 - 0.0024 17.9 0.1 0.0025 17.9 0.1 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Retrotran_gag_2 PF14223.6 EIM85844.1 - 1.4e-20 73.3 0.8 1.8e-20 73.0 0.8 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EIM85844.1 - 0.00064 19.5 0.1 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.22 EIM85844.1 - 0.098 12.3 0.1 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DUF3484 PF11983.8 EIM85846.1 - 0.11 13.6 0.1 0.17 13.0 0.1 1.3 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch zf-CCHC PF00098.23 EIM85847.1 - 5.5e-05 23.1 9.9 0.016 15.2 1.7 2.3 2 0 0 2 2 2 2 Zinc knuckle Nudix_N_2 PF14803.6 EIM85847.1 - 0.025 14.5 3.2 0.064 13.2 3.2 1.7 1 0 0 1 1 1 0 Nudix N-terminal Dimer_Tnp_hAT PF05699.14 EIM85850.1 - 7.5e-08 32.1 0.1 8e-08 32.0 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Helicase_C_2 PF13307.6 EIM85851.1 - 2.2e-52 177.7 0.0 1.3e-51 175.2 0.0 2.3 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EIM85851.1 - 6.6e-45 152.9 0.1 3.2e-39 134.4 0.0 2.5 2 0 0 2 2 2 2 DEAD_2 ResIII PF04851.15 EIM85851.1 - 1.2e-06 28.7 0.0 0.018 15.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIM85851.1 - 0.0012 19.1 0.0 0.67 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain DEAD PF00270.29 EIM85851.1 - 0.0016 18.2 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EIM85851.1 - 0.036 13.3 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EIM85851.1 - 0.043 13.3 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 EIM85851.1 - 0.083 11.9 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EIM85851.1 - 0.4 10.4 4.7 0.54 9.9 0.0 3.1 4 0 0 4 4 4 0 AAA domain ERG4_ERG24 PF01222.17 EIM85852.1 - 2.6e-138 461.4 2.3 3e-138 461.2 2.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIM85852.1 - 3.4e-05 23.5 0.2 8.6e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EIM85852.1 - 6.6e-05 23.3 0.0 6.6e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 EIM85852.1 - 0.00046 20.6 0.0 0.0015 18.9 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Na_Ca_ex PF01699.24 EIM85854.1 - 9.9e-19 67.8 34.1 7.7e-11 42.2 11.6 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 EIM85854.1 - 3e-13 50.3 16.0 3e-13 50.3 16.0 4.1 4 0 0 4 4 4 1 Inner membrane component domain DUF4149 PF13664.6 EIM85854.1 - 1.4 9.2 7.2 0.36 11.2 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Carn_acyltransf PF00755.20 EIM85855.1 - 6.1e-197 655.9 0.0 6.9e-197 655.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase KdgT PF03812.13 EIM85856.1 - 0.46 9.8 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease Mito_carr PF00153.27 EIM85857.1 - 2.6e-73 242.0 0.3 6.8e-26 90.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NTP_transf_9 PF04248.12 EIM85858.1 - 2.1e-32 110.9 1.0 2.3e-32 110.7 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) UvrB_inter PF17757.1 EIM85858.1 - 0.032 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 UvrB interaction domain DUF3684 PF12449.8 EIM85859.1 - 0 1204.1 0.0 0 1203.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) DUF2076 PF09849.9 EIM85859.1 - 0.036 14.1 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HATPase_c_3 PF13589.6 EIM85859.1 - 0.045 13.6 0.0 0.32 10.8 0.0 2.4 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GFA PF04828.14 EIM85860.1 - 5.5e-16 58.7 0.8 8.4e-16 58.1 0.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 EIM85860.1 - 0.006 16.7 1.7 0.72 10.1 0.0 2.3 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.16 EIM85860.1 - 0.16 12.2 2.8 0.22 11.9 0.1 2.0 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-A20 PF01754.16 EIM85860.1 - 9 6.3 11.5 0.25 11.3 3.1 2.3 2 0 0 2 2 2 0 A20-like zinc finger Di19_C PF14571.6 EIM85861.1 - 0.018 15.5 0.5 0.023 15.2 0.5 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal HA2 PF04408.23 EIM85862.1 - 1.5e-23 83.2 0.0 2.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIM85862.1 - 5.3e-20 71.6 0.3 1e-19 70.6 0.3 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Sacchrp_dh_NADP PF03435.18 EIM85862.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HpcH_HpaI PF03328.14 EIM85863.1 - 2.3e-44 151.2 0.0 3.5e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EIM85863.1 - 4.7e-12 45.7 0.0 6.8e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CwfJ_C_2 PF04676.14 EIM85864.1 - 1.2e-36 125.5 0.3 4.9e-36 123.6 0.1 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EIM85864.1 - 1.6e-32 111.9 0.0 2.3e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.25 EIM85865.1 - 3.7e-63 213.4 0.0 8.3e-63 212.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85865.1 - 6.1e-36 124.0 0.0 1.3e-35 122.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EIM85865.1 - 3.5e-21 75.1 19.7 5.2e-14 52.1 3.8 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EIM85865.1 - 1.2e-20 73.1 28.6 6.6e-12 45.1 11.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EIM85865.1 - 2.6e-10 40.8 0.7 2.6e-10 40.8 0.7 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 EIM85865.1 - 1.9e-09 37.7 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain FTA2 PF13095.6 EIM85865.1 - 0.049 13.3 0.1 1.3 8.6 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EIM85865.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain C1_2 PF03107.16 EIM85865.1 - 0.14 12.4 22.0 0.92 9.9 8.1 2.4 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 EIM85865.1 - 0.97 9.6 14.4 1.2 9.3 1.8 2.7 2 0 0 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.16 EIM85865.1 - 3.2 8.0 16.4 6.2 7.1 3.1 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger Endosulfine PF04667.17 EIM85866.1 - 3.5e-28 97.6 0.6 4.7e-28 97.1 0.0 1.5 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_E_B PF04042.16 EIM85868.1 - 1.9e-27 96.0 0.1 2.7e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EIM85868.1 - 3.2e-23 83.0 0.1 3.3e-14 53.5 0.2 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.6 EIM85868.1 - 0.14 11.4 0.0 0.79 9.0 0.0 1.9 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily L_protein_N PF15518.6 EIM85868.1 - 0.14 12.0 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 L protein N-terminus SET PF00856.28 EIM85869.1 - 5.9e-21 75.6 0.0 5.9e-21 75.6 0.0 2.6 3 2 0 3 3 3 1 SET domain Pre-SET PF05033.16 EIM85869.1 - 2.6e-14 53.8 3.6 2.6e-14 53.8 3.6 2.2 2 0 0 2 2 2 1 Pre-SET motif Metallothio_Euk PF12749.7 EIM85869.1 - 7.6 6.8 18.5 2.9 8.1 3.5 3.2 3 0 0 3 3 3 0 Eukaryotic metallothionein RasGEF PF00617.19 EIM85870.1 - 1e-57 195.2 0.4 4.3e-57 193.2 0.7 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EIM85870.1 - 4.3e-19 68.7 1.2 4.3e-19 68.7 1.2 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 EIM85870.1 - 3.2e-17 61.9 0.3 7.5e-17 60.7 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM85870.1 - 1.9e-12 46.8 0.2 4.8e-12 45.5 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIM85870.1 - 9.2e-12 44.5 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EIM85870.1 - 1.8e-05 24.7 2.2 0.03 14.4 0.0 2.9 3 0 0 3 3 3 2 WW domain DUF1601 PF07671.11 EIM85870.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DUF416 PF04222.12 EIM85870.1 - 0.16 11.4 0.6 0.58 9.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF416) GTP_EFTU PF00009.27 EIM85871.1 - 2.4e-55 187.1 0.0 3.8e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EIM85871.1 - 3.7e-08 33.3 0.0 8.7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EIM85871.1 - 2e-07 31.0 0.0 4.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EIM85871.1 - 1.7e-06 28.3 0.2 6.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM85871.1 - 2.5e-05 24.3 0.1 6.4e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 EIM85871.1 - 0.004 16.9 0.1 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV SRPRB PF09439.10 EIM85871.1 - 0.066 12.6 0.1 0.28 10.6 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EIM85871.1 - 0.17 11.8 0.3 1.6 8.6 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EIM85872.1 - 5.7e-47 159.6 0.1 7.8e-47 159.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EIM85872.1 - 1.8e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EIM85872.1 - 2.6e-05 24.2 0.1 0.21 11.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EIM85872.1 - 5.5e-05 23.2 0.0 0.00012 22.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIM85872.1 - 0.00012 21.6 0.1 0.035 13.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.21 EIM85872.1 - 0.0053 16.2 0.7 0.36 10.3 0.4 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family MeaB PF03308.16 EIM85872.1 - 0.011 14.7 0.4 0.3 10.0 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EIM85872.1 - 0.012 15.3 0.1 0.031 14.0 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EIM85872.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EIM85872.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain UAA PF08449.11 EIM85873.1 - 1.1e-42 146.3 9.1 2.5e-42 145.2 9.1 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EIM85873.1 - 1e-07 32.2 26.9 1.5e-06 28.4 11.8 4.5 3 1 2 5 5 5 3 EamA-like transporter family Nuc_sug_transp PF04142.15 EIM85873.1 - 0.0041 16.3 4.2 0.76 8.9 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 EIM85873.1 - 0.16 10.9 7.4 0.61 9.0 0.7 2.5 3 0 0 3 3 3 0 CRT-like, chloroquine-resistance transporter-like FMO-like PF00743.19 EIM85874.1 - 6.5e-13 47.9 0.0 8.3e-07 27.8 0.0 2.9 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM85874.1 - 1.7e-11 43.9 0.0 1.1e-10 41.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM85874.1 - 1.8e-09 37.7 0.0 5.8e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EIM85874.1 - 2.8e-08 33.4 0.1 0.0057 16.0 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM85874.1 - 5.2e-06 26.3 0.0 0.0025 17.5 0.0 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM85874.1 - 1.2e-05 24.2 0.0 1.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 EIM85874.1 - 9.7e-05 22.4 0.1 0.004 17.2 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIM85874.1 - 0.00011 21.4 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EIM85874.1 - 0.00033 20.1 0.5 0.087 12.1 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EIM85874.1 - 0.00044 19.6 0.0 0.00096 18.5 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EIM85874.1 - 0.00052 20.5 0.0 0.0021 18.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM85874.1 - 0.0012 18.0 0.0 0.66 9.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EIM85874.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EIM85874.1 - 0.0026 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EIM85874.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EIM85874.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EIM85874.1 - 0.04 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIM85875.1 - 2.3e-61 208.0 0.0 3.1e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM85875.1 - 7.5e-10 38.5 0.8 0.00025 20.4 0.0 3.3 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM85875.1 - 7.3e-07 28.4 0.2 4e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 EIM85875.1 - 3.6e-06 27.5 0.0 0.022 15.3 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM85875.1 - 1.9e-05 24.8 0.2 5.4e-05 23.3 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM85875.1 - 1.9e-05 24.1 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EIM85875.1 - 3e-05 22.9 0.0 0.0017 17.1 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EIM85875.1 - 7.5e-05 22.5 1.4 0.0076 15.9 0.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EIM85875.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM85875.1 - 0.0034 16.7 0.0 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Cytochrom_C PF00034.21 EIM85875.1 - 0.0042 18.2 0.0 0.016 16.4 0.0 1.9 1 1 1 2 2 2 1 Cytochrome c FAD_binding_2 PF00890.24 EIM85875.1 - 0.0056 15.8 0.1 0.018 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EIM85875.1 - 0.015 14.4 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A MAF_flag10 PF01973.18 EIM85875.1 - 0.12 12.1 0.1 24 4.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF115 FAD_binding_1 PF00667.20 EIM85876.1 - 3.1e-56 190.4 0.0 1.9e-55 187.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EIM85876.1 - 3.1e-31 108.5 1.1 4.1e-31 108.1 0.2 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EIM85876.1 - 2.6e-19 69.9 0.0 6.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EIM85876.1 - 0.082 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain She9_MDM33 PF05546.11 EIM85877.1 - 4.6e-72 242.0 9.0 6.7e-72 241.5 9.0 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF2371 PF10177.9 EIM85877.1 - 0.21 11.8 0.8 0.46 10.6 0.3 1.8 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) RIC3 PF15361.6 EIM85877.1 - 0.23 11.8 3.1 0.91 9.9 3.1 2.1 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 MbeB_N PF04837.12 EIM85877.1 - 0.27 11.6 7.1 0.57 10.5 0.3 3.5 3 0 0 3 3 3 0 MbeB-like, N-term conserved region XRN_M PF17846.1 EIM85877.1 - 0.39 9.6 3.9 0.55 9.1 3.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Uso1_p115_C PF04871.13 EIM85877.1 - 6.1 7.2 17.1 0.92 9.9 2.5 3.0 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Leader_Trp PF08255.11 EIM85878.1 - 0.077 13.0 0.4 0.077 13.0 0.4 2.9 3 0 0 3 3 3 0 Trp-operon Leader Peptide HIT PF01230.23 EIM85879.1 - 3.2e-20 72.7 0.2 4.9e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EIM85879.1 - 7.1e-15 55.5 0.0 9.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EIM85879.1 - 2.9e-07 30.4 0.0 4.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 PGM_PMM_I PF02878.16 EIM85880.1 - 1.9e-38 131.3 0.0 4.4e-38 130.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EIM85880.1 - 5.6e-24 84.7 0.0 1.4e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EIM85880.1 - 2.1e-18 66.6 0.3 1.7e-17 63.6 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EIM85880.1 - 1.5e-05 25.0 0.0 5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SOG2 PF10428.9 EIM85881.1 - 0.41 9.8 25.5 0.49 9.5 25.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 EIM85881.1 - 0.45 10.1 14.1 0.59 9.7 14.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SLC12 PF03522.15 EIM85881.1 - 0.89 8.5 8.6 1.1 8.2 8.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 EIM85881.1 - 1 7.9 22.0 1.6 7.2 22.0 1.3 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 EIM85881.1 - 1.8 6.6 12.4 2.2 6.3 12.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.13 EIM85881.1 - 1.9 6.9 25.0 2.4 6.6 25.0 1.0 1 0 0 1 1 1 0 Utp14 protein MCM_bind PF09739.9 EIM85882.1 - 1e-78 265.3 0.0 4.9e-67 226.7 0.0 2.9 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor CBFD_NFYB_HMF PF00808.23 EIM85883.1 - 6.9e-15 55.1 3.1 6.9e-15 55.1 3.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM85883.1 - 7.2e-12 45.8 5.4 1.1e-11 45.2 5.4 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIM85883.1 - 0.0033 17.5 0.1 0.0048 17.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-W PF15510.6 EIM85883.1 - 0.029 14.6 0.2 0.037 14.2 0.2 1.2 1 0 0 1 1 1 0 CENP-W protein TAF4 PF05236.14 EIM85883.1 - 0.039 13.7 1.3 0.049 13.4 1.3 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MMS1_N PF10433.9 EIM85884.1 - 7.9e-67 226.0 0.0 1.3e-66 225.2 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EIM85884.1 - 1e-44 153.2 0.1 3.3e-43 148.3 0.0 3.3 5 0 0 5 5 5 1 CPSF A subunit region Peptidase_C97 PF05903.14 EIM85886.1 - 8.6e-43 145.8 0.0 1.3e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 EIM85886.1 - 6.3e-35 120.7 2.7 1.2e-34 119.8 2.7 1.4 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 EIM85886.1 - 1.3e-13 50.8 0.0 3.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIM85886.1 - 0.00046 20.6 0.3 0.0062 17.0 0.3 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EIM85886.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 EIM85886.1 - 0.097 12.4 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Redoxin Asp PF00026.23 EIM85888.1 - 1.4e-44 152.8 4.4 3.4e-44 151.6 4.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EIM85888.1 - 6.9e-05 23.4 0.5 0.00016 22.3 0.5 1.6 1 0 0 1 1 1 1 Aspartyl protease TAXi_N PF14543.6 EIM85888.1 - 0.00042 20.6 3.3 0.06 13.6 0.6 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal AOX PF01786.17 EIM85890.1 - 8e-97 323.0 0.1 9.4e-97 322.8 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase PH_4 PF15404.6 EIM85891.1 - 3.9e-15 56.1 1.0 5.9e-13 49.0 1.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain DUF4436 PF14494.6 EIM85892.1 - 5.1e-14 52.2 3.9 5.1e-14 52.2 3.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4436) Barttin PF15462.6 EIM85892.1 - 0.14 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) TRP_N PF14558.6 EIM85892.1 - 0.15 12.4 1.5 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 ML-like domain Pkinase_fungal PF17667.1 EIM85893.1 - 2.5e-53 181.4 0.0 7.3e-33 113.9 0.0 2.4 1 1 0 2 2 2 2 Fungal protein kinase Pkinase_Tyr PF07714.17 EIM85893.1 - 0.029 13.6 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 EIM85893.1 - 0.13 11.5 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein kinase domain Ribosom_S12_S23 PF00164.25 EIM85894.1 - 6e-33 112.9 1.2 7.1e-33 112.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 zf-Nse PF11789.8 EIM85895.1 - 1e-14 54.1 0.0 1.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EIM85895.1 - 0.0026 17.7 1.4 0.0038 17.2 0.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM85895.1 - 0.0038 17.0 0.1 0.0075 16.1 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM85895.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 EIM85895.1 - 0.051 13.3 0.2 0.089 12.6 0.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF948 PF06103.11 EIM85895.1 - 0.3 11.4 3.5 0.25 11.6 0.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 EIM85895.1 - 7.6 6.6 25.5 0.11 12.5 3.2 3.8 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain UPF0014 PF03649.13 EIM85896.1 - 1.6e-66 224.1 19.8 2e-66 223.8 19.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.22 EIM85896.1 - 0.16 11.7 18.5 0.78 9.4 18.3 2.1 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component NAD_binding_6 PF08030.12 EIM85897.1 - 1.3e-21 77.3 0.0 2.1e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EIM85897.1 - 9.7e-21 74.2 6.1 9.7e-21 74.2 6.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIM85897.1 - 9.2e-12 45.0 0.0 1.2e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain F-box-like PF12937.7 EIM85898.1 - 1.2e-05 25.1 2.0 0.00012 21.9 2.0 2.5 1 1 0 1 1 1 1 F-box-like ADH_N PF08240.12 EIM85900.1 - 4.8e-26 90.8 1.1 1e-25 89.7 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM85900.1 - 2e-09 37.5 0.1 3.8e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EIM85900.1 - 5.4e-06 26.2 0.1 1.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 EIM85900.1 - 1.5e-05 24.6 0.0 7.5e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 EIM85900.1 - 0.00041 19.2 0.2 0.0035 16.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EIM85900.1 - 0.0032 16.8 0.1 0.0053 16.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EIM85900.1 - 0.025 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EIM85900.1 - 0.039 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EIM85900.1 - 0.065 12.6 0.3 0.09 12.1 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 EIM85900.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM85900.1 - 0.079 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EHN PF06441.12 EIM85901.1 - 2.8e-33 114.5 3.6 3.4e-33 114.2 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EIM85901.1 - 1.9e-11 44.1 0.1 3.1e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Integrin_b_cyt PF08725.11 EIM85901.1 - 0.024 14.3 0.1 8.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Abhydrolase_6 PF12697.7 EIM85901.1 - 0.45 11.1 9.9 0.43 11.1 6.2 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family HA2 PF04408.23 EIM85902.1 - 4.1e-20 72.1 0.0 7.8e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIM85902.1 - 9.6e-15 54.9 0.0 2.7e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EIM85902.1 - 1.5e-10 41.2 0.0 4.3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EIM85902.1 - 1.7e-07 31.2 0.5 3.6e-07 30.1 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIM85902.1 - 1.3e-05 25.4 0.1 2.7e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM85902.1 - 9.1e-05 22.8 0.1 0.00029 21.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM85902.1 - 0.00043 20.0 0.2 0.0008 19.2 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EIM85902.1 - 0.0018 18.8 0.2 0.034 14.7 0.1 2.5 1 1 1 2 2 2 1 ABC transporter AAA_29 PF13555.6 EIM85902.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_A_amyl_C PF18612.1 EIM85902.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial Alpha amylase C-terminal domain AAA_5 PF07728.14 EIM85902.1 - 0.15 12.0 0.3 29 4.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Alpha_L_fucos PF01120.17 EIM85903.1 - 2.5e-33 116.0 0.0 3.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 EIM85903.1 - 9.8e-06 25.7 0.1 2.1e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain 4HBT PF03061.22 EIM85904.1 - 2.5e-09 37.3 0.0 0.00057 20.2 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily POT1 PF02765.17 EIM85905.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 p450 PF00067.22 EIM85906.1 - 5.4e-45 154.0 0.0 6.3e-26 91.1 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 Filo_glycop PF01611.16 EIM85906.1 - 0.12 11.3 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein cobW PF02492.19 EIM85907.1 - 1e-26 93.6 0.0 2.3e-26 92.4 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EIM85907.1 - 0.0012 17.9 0.2 0.038 13.0 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EIM85907.1 - 0.039 14.5 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EIM85907.1 - 0.072 12.6 0.1 5.5 6.5 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ResIII PF04851.15 EIM85907.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 EIM85907.1 - 0.25 11.2 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SNF2_N PF00176.23 EIM85909.1 - 2.4e-52 177.8 0.8 3.5e-52 177.3 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM85909.1 - 2.3e-20 73.0 0.0 2.9e-18 66.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EIM85909.1 - 1e-06 28.2 0.1 8.4e-06 25.1 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 EIM85909.1 - 0.00035 20.4 21.4 0.00093 19.0 10.3 3.0 2 1 1 3 3 3 2 PHD-finger DEAD PF00270.29 EIM85909.1 - 0.00048 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Adeno_terminal PF02459.15 EIM85909.1 - 0.021 13.3 2.7 0.04 12.3 2.7 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein C1_2 PF03107.16 EIM85909.1 - 1.4 9.3 18.0 0.15 12.4 2.5 2.5 2 0 0 2 2 2 0 C1 domain HVSL PF09749.9 EIM85910.1 - 5.1e-42 144.0 0.0 2.5e-41 141.7 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 EIM85910.1 - 0.00025 21.0 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Cdh1_DBD_1 PF18196.1 EIM85911.1 - 0.042 14.2 1.1 0.042 14.2 1.1 3.8 2 2 1 4 4 4 0 Chromodomain helicase DNA-binding domain 1 DGF-1_C PF11040.8 EIM85911.1 - 0.16 12.0 3.6 0.58 10.2 3.6 2.0 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus p450 PF00067.22 EIM85912.1 - 4.4e-64 216.9 0.0 5e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2706 PF10913.8 EIM85913.1 - 0.021 14.6 2.2 0.67 9.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) NAD_binding_7 PF13241.6 EIM85913.1 - 0.087 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding Rft-1 PF04506.13 EIM85914.1 - 3e-131 438.7 0.9 3.6e-131 438.4 0.9 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EIM85914.1 - 1.4e-07 31.0 2.8 1.4e-07 31.0 2.8 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 EIM85914.1 - 1.5e-06 27.8 8.4 1.5e-06 27.8 8.4 2.8 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein DUF5058 PF16481.5 EIM85914.1 - 0.06 13.0 1.5 0.47 10.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5058) 2TM PF13239.6 EIM85914.1 - 0.26 11.6 1.2 0.65 10.3 0.2 2.3 2 0 0 2 2 2 0 2TM domain ADH_zinc_N PF00107.26 EIM85916.1 - 1.7e-15 57.2 0.1 2.7e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM85916.1 - 4.3e-07 29.8 0.1 8.2e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM85916.1 - 1.4e-05 26.1 0.0 2.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Yae1_N PF09811.9 EIM85919.1 - 2.4e-11 43.1 1.7 4e-11 42.4 1.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Acyl-CoA_dh_2 PF08028.11 EIM85919.1 - 0.084 13.2 0.7 0.14 12.4 0.7 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Octopine_DH PF02317.17 EIM85919.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.7 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Apolipoprotein PF01442.18 EIM85919.1 - 0.2 11.5 5.2 0.22 11.4 3.0 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Dynactin_p62 PF05502.13 EIM85920.1 - 2.7e-74 250.7 7.8 3.5e-44 151.4 3.9 2.1 2 0 0 2 2 2 2 Dynactin p62 family Host_attach PF10116.9 EIM85921.1 - 1.7 9.2 5.7 0.3 11.7 0.7 2.0 2 0 0 2 2 2 0 Protein required for attachment to host cells Rft-1 PF04506.13 EIM85923.1 - 3.6e-133 445.0 1.9 4.1e-133 444.8 1.9 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EIM85923.1 - 1.9e-07 30.6 3.0 1.9e-07 30.6 3.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 EIM85923.1 - 1.4e-06 27.9 8.7 1.4e-06 27.9 8.7 2.7 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein DUF5058 PF16481.5 EIM85923.1 - 0.018 14.8 3.0 0.57 9.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5058) 2TM PF13239.6 EIM85923.1 - 2.2 8.7 3.9 8.7 6.7 3.9 2.1 1 1 0 1 1 1 0 2TM domain Asp PF00026.23 EIM85925.1 - 9.3e-23 81.1 8.1 6.2e-20 71.8 8.1 2.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Orthoreo_P10 PF07204.11 EIM85925.1 - 0.00061 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 gag-asp_proteas PF13975.6 EIM85925.1 - 0.00068 20.1 2.5 0.69 10.5 0.2 3.9 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIM85925.1 - 0.0044 17.6 2.2 0.63 10.7 0.7 3.4 2 2 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 EIM85925.1 - 0.025 14.8 1.3 2.6 8.2 0.1 2.4 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Asp PF00026.23 EIM85926.1 - 1.3e-22 80.6 6.4 3.6e-20 72.6 6.4 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 EIM85926.1 - 0.0018 18.8 0.1 7.9 7.1 0.1 3.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIM85926.1 - 0.038 14.6 1.8 3.9 8.2 0.4 3.3 3 1 0 3 3 3 0 Aspartyl protease LapA_dom PF06305.11 EIM85926.1 - 0.091 12.6 0.2 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain eIF2A PF08662.11 EIM85927.1 - 1.7e-38 132.4 0.1 2e-34 119.2 0.0 4.3 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EIM85927.1 - 3.1e-06 26.9 0.0 8.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 EIM85927.1 - 0.00015 22.0 0.3 59 4.1 0.0 5.8 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM85927.1 - 0.0007 20.4 2.5 1.4 9.9 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF4254 PF14063.6 EIM85927.1 - 0.0016 18.3 2.5 0.0027 17.5 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) F-box-like PF12937.7 EIM85928.1 - 8.2e-11 41.6 0.7 8.2e-11 41.6 0.7 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EIM85928.1 - 0.0068 16.3 3.4 1.3 9.0 0.0 3.2 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.7 EIM85928.1 - 0.63 10.5 7.6 42 4.7 0.2 4.9 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_S9 PF00326.21 EIM85929.1 - 7.1e-47 159.6 0.1 1.2e-46 158.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EIM85929.1 - 5.4e-05 23.0 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 EIM85929.1 - 7.3e-05 21.6 0.0 0.0081 14.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Lipid_DES PF08557.10 EIM85929.1 - 0.42 10.1 3.6 13 5.4 0.1 2.5 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) NDK PF00334.19 EIM85930.1 - 1.2e-13 51.2 0.0 3.3e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Nucleoside diphosphate kinase Aldo_ket_red PF00248.21 EIM85931.1 - 5e-64 216.3 0.0 5.7e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IMPa_N_2 PF18650.1 EIM85931.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Aldo_ket_red PF00248.21 EIM85932.1 - 3.9e-63 213.4 0.0 4.5e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IMPa_N_2 PF18650.1 EIM85932.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Ribosomal_L34 PF00468.17 EIM85933.1 - 5e-20 71.2 9.2 5e-20 71.2 9.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L34 zf-RING_2 PF13639.6 EIM85934.1 - 1.1e-11 44.9 1.9 2.1e-11 44.0 1.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EIM85934.1 - 1.4e-11 43.9 0.9 1.4e-11 43.9 0.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 EIM85934.1 - 2.3e-09 37.2 0.0 4.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 EIM85934.1 - 1e-06 28.6 0.4 2.1e-06 27.6 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM85934.1 - 7.5e-06 25.7 1.5 7.5e-06 25.7 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM85934.1 - 0.00013 21.7 1.8 0.00016 21.5 0.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM85934.1 - 0.00023 21.4 3.1 0.0014 18.9 3.1 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EIM85934.1 - 0.00045 20.2 3.8 0.0051 16.8 0.1 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM85934.1 - 0.00064 19.5 1.9 0.002 17.9 1.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM85934.1 - 0.0089 15.9 1.6 0.02 14.7 1.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EIM85934.1 - 0.046 13.3 1.6 0.084 12.5 1.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EIM85934.1 - 0.072 13.2 0.7 0.23 11.5 0.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-CCCH PF00642.24 EIM85935.1 - 1.4e-14 53.5 23.0 4.2e-08 32.9 4.8 3.6 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIM85935.1 - 4.5e-12 45.6 20.4 2.8e-07 30.4 2.8 4.2 3 1 0 3 3 3 3 Zinc finger domain Torus PF16131.5 EIM85935.1 - 4.2e-07 30.6 5.5 0.025 15.3 0.2 3.3 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 EIM85935.1 - 2.1e-06 27.4 22.6 0.0055 16.5 2.1 3.9 3 1 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EIM85935.1 - 0.00078 19.8 22.1 0.031 14.7 3.6 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Lustrin_cystein PF14625.6 EIM85935.1 - 0.043 14.2 1.6 2.2 8.7 0.1 2.6 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain zf-CCCH_3 PF15663.5 EIM85935.1 - 0.21 11.8 8.7 0.71 10.1 2.0 3.1 3 0 0 3 3 3 0 Zinc-finger containing family MFS_1 PF07690.16 EIM85937.1 - 3.1e-23 82.3 39.5 6.5e-15 54.9 14.8 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85937.1 - 4.7e-20 71.9 19.5 4.2e-19 68.7 1.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_16 PF00722.21 EIM85938.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 adh_short PF00106.25 EIM85939.1 - 1e-24 87.1 0.0 6e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM85939.1 - 8e-18 64.8 0.0 7.4e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM85939.1 - 3.7e-05 23.3 0.0 0.00043 19.8 0.0 2.1 1 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM85939.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 1 0 1 1 1 1 KR domain ARGLU PF15346.6 EIM85939.1 - 0.024 14.5 0.3 0.037 13.9 0.3 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 SET PF00856.28 EIM85940.1 - 6.4e-10 39.7 0.0 1.1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EIM85940.1 - 4.6e-08 33.0 12.0 4.6e-08 33.0 12.0 1.7 2 0 0 2 2 2 1 MYND finger DER1 PF04511.15 EIM85941.1 - 1.4e-46 158.8 5.6 1.7e-46 158.6 5.6 1.0 1 0 0 1 1 1 1 Der1-like family Jiraiya PF15038.6 EIM85941.1 - 0.12 11.8 0.2 0.12 11.8 0.2 1.8 3 0 0 3 3 3 0 Jiraiya YTH PF04146.15 EIM85942.1 - 9.5e-61 204.6 0.2 2.3e-60 203.3 0.2 1.7 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 EIM85942.1 - 5.8e-07 29.2 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_71 PF03659.14 EIM85944.1 - 1.5e-105 353.1 11.7 3.9e-105 351.7 11.7 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.19 EIM85944.1 - 5.9e-68 225.1 93.8 5.9e-18 64.8 12.9 5.2 5 0 0 5 5 5 4 WSC domain CBM_20 PF00686.19 EIM85944.1 - 4.1e-29 100.3 0.4 4.1e-29 100.3 0.4 4.1 5 0 0 5 5 5 1 Starch binding domain AMPK1_CBM PF16561.5 EIM85944.1 - 0.00053 20.2 0.0 0.0019 18.4 0.0 1.9 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glyco_hydro_15 PF00723.21 EIM85945.1 - 2.1e-97 326.7 2.4 2.5e-97 326.5 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EIM85945.1 - 4e-28 97.2 0.4 1e-27 95.9 0.4 1.7 1 0 0 1 1 1 1 Starch binding domain TPR_1 PF00515.28 EIM85946.1 - 7.7e-07 28.7 0.0 0.81 9.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box-like PF12937.7 EIM85946.1 - 2.1e-06 27.5 2.8 2.1e-06 27.5 2.8 2.0 2 0 0 2 2 2 1 F-box-like TPR_2 PF07719.17 EIM85946.1 - 3.5e-06 26.7 0.0 0.013 15.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM85946.1 - 0.0059 16.9 0.0 0.031 14.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM85946.1 - 0.016 15.4 0.2 61 4.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.7 EIM85946.1 - 0.041 14.3 6.0 1.4 9.4 0.0 5.3 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) TPR_9 PF13371.6 EIM85946.1 - 0.042 14.0 0.0 12 6.1 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIM85946.1 - 0.068 13.7 1.6 3.9 8.1 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 EIM85948.1 - 1.2e-40 139.0 0.0 2.4e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EIM85948.1 - 4.5e-20 71.4 0.1 9.2e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EIM85948.1 - 6.3e-12 45.1 0.1 1.5e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIM85948.1 - 7.2e-05 23.2 0.2 0.016 15.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EIM85948.1 - 0.00024 21.1 0.2 0.0023 17.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EIM85948.1 - 0.00059 20.0 0.0 0.0095 16.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EIM85948.1 - 0.00093 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIM85948.1 - 0.00096 19.4 0.4 0.052 13.8 0.4 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EIM85948.1 - 0.0023 17.4 0.1 0.049 13.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 EIM85948.1 - 0.004 17.3 0.0 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EIM85948.1 - 0.0089 15.4 0.1 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EIM85948.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EIM85948.1 - 0.031 14.1 0.1 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIM85948.1 - 0.057 13.1 0.1 0.18 11.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EIM85948.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NuA4 PF09340.10 EIM85949.1 - 1.5e-23 82.5 0.5 1.5e-23 82.5 0.5 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 GPS2_interact PF15784.5 EIM85949.1 - 0.002 18.5 0.8 0.0051 17.2 0.0 2.0 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain Wbp11 PF09429.10 EIM85949.1 - 0.26 11.7 7.0 1.5 9.3 0.9 2.6 2 1 0 2 2 2 0 WW domain binding protein 11 Rrp40_N PF18311.1 EIM85950.1 - 3.2e-14 52.6 0.4 6.7e-14 51.5 0.2 1.6 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EIM85950.1 - 9.1e-12 45.1 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 KH domain CID_GANP PF16766.5 EIM85950.1 - 0.19 11.9 0.1 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Binding region of GANP to ENY2 Mod_r PF07200.13 EIM85951.1 - 1e-45 155.4 5.5 1.2e-45 155.2 5.5 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 EIM85951.1 - 0.0019 18.2 4.7 0.0019 18.2 4.7 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.11 EIM85951.1 - 0.0033 17.9 2.7 0.01 16.3 0.7 2.3 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF4515 PF14988.6 EIM85951.1 - 0.025 14.4 5.5 0.038 13.8 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) CENP-H PF05837.12 EIM85951.1 - 0.11 12.9 3.5 0.18 12.2 3.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) OmpH PF03938.14 EIM85951.1 - 0.14 12.5 6.7 0.24 11.7 6.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF349 PF03993.12 EIM85951.1 - 1.7 9.0 8.4 5.6 7.3 7.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) ZapB PF06005.12 EIM85951.1 - 1.7 9.2 10.5 1.5 9.3 2.7 2.6 1 1 2 3 3 3 0 Cell division protein ZapB CwsA PF10814.8 EIM85951.1 - 5.5 7.2 5.9 17 5.6 5.9 1.8 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA Glyco_hydro_61 PF03443.14 EIM85952.1 - 5.7e-63 212.6 0.6 6.7e-63 212.3 0.1 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 NCA2 PF08637.10 EIM85953.1 - 6.2e-79 265.2 0.0 1e-78 264.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Epimerase PF01370.21 EIM85955.1 - 1.1e-16 61.0 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM85955.1 - 8.4e-14 51.2 0.1 1.3e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM85955.1 - 2.6e-09 36.6 0.6 6e-08 32.2 0.6 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIM85955.1 - 4e-09 36.3 0.0 6.5e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM85955.1 - 2.6e-07 30.7 0.1 5.5e-07 29.7 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EIM85955.1 - 0.0068 15.9 0.2 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EIM85955.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_18 PF15024.6 EIM85956.1 - 2.8e-07 29.5 0.1 0.0024 16.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 18 DUF3915 PF13054.6 EIM85956.1 - 0.033 14.2 1.6 0.033 14.2 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) RasGEF PF00617.19 EIM85957.1 - 7.5e-49 166.3 0.0 1.6e-48 165.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EIM85957.1 - 1.7e-20 73.2 0.0 6e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_2 PF07653.17 EIM85957.1 - 9.5e-13 47.6 0.0 1.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EIM85957.1 - 1.4e-12 47.3 0.0 2.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIM85957.1 - 2.1e-11 43.2 0.0 4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain F-box PF00646.33 EIM85958.1 - 1.1e-05 25.1 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM85958.1 - 0.00018 21.4 0.7 0.00033 20.5 0.7 1.5 1 0 0 1 1 1 1 F-box-like SPX PF03105.19 EIM85958.1 - 0.56 10.1 7.3 0.76 9.6 7.3 1.2 1 0 0 1 1 1 0 SPX domain EF_assoc_2 PF08356.12 EIM85959.1 - 1.7e-36 124.1 0.0 3.3e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EIM85959.1 - 2.1e-29 100.9 0.7 4.4e-29 99.9 0.7 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EIM85959.1 - 2.6e-24 85.6 0.0 2e-19 69.8 0.0 3.2 3 0 0 3 3 3 1 Ras family Roc PF08477.13 EIM85959.1 - 4.7e-16 59.1 0.0 7.7e-10 39.0 0.0 3.4 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 EIM85959.1 - 2.8e-10 39.0 1.3 0.00061 19.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EIM85959.1 - 5.6e-10 38.3 0.2 0.00033 20.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EIM85959.1 - 8.8e-10 38.9 0.1 0.00029 21.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EIM85959.1 - 4.7e-08 32.2 3.0 0.0045 16.4 0.2 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.21 EIM85959.1 - 4.8e-08 32.6 0.0 0.0016 18.0 0.0 3.3 3 1 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM85959.1 - 2.4e-06 27.6 0.0 0.0065 16.6 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM85959.1 - 6e-06 26.7 0.2 0.19 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EIM85959.1 - 7.6e-06 26.1 0.6 0.087 12.9 0.0 3.1 3 0 0 3 3 3 2 Dynamin family AAA_22 PF13401.6 EIM85959.1 - 2.1e-05 24.8 0.0 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EIM85959.1 - 4.5e-05 23.4 0.1 0.4 10.6 0.0 3.8 4 0 0 4 4 4 1 RsgA GTPase AAA_18 PF13238.6 EIM85959.1 - 7.2e-05 23.3 0.0 0.23 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EIM85959.1 - 0.0001 22.8 0.0 0.43 11.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA PF00004.29 EIM85959.1 - 0.00013 22.4 0.0 0.27 11.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EIM85959.1 - 0.00018 21.7 0.1 1.2 9.3 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EIM85959.1 - 0.00019 21.1 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 EIM85959.1 - 0.00019 21.8 0.1 1.1 9.7 0.0 3.4 3 0 0 3 3 3 1 RNA helicase EF-hand_10 PF14788.6 EIM85959.1 - 0.00024 20.9 2.7 0.0079 16.0 0.1 2.4 2 0 0 2 2 2 1 EF hand NACHT PF05729.12 EIM85959.1 - 0.00042 20.3 0.1 0.77 9.7 0.1 2.6 2 0 0 2 2 2 2 NACHT domain Septin PF00735.18 EIM85959.1 - 0.00048 19.5 0.0 0.05 12.9 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 EIM85959.1 - 0.0015 18.3 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EIM85959.1 - 0.0017 17.8 0.0 3.1 7.2 0.0 2.9 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EIM85959.1 - 0.0027 16.9 0.3 1.9 7.5 0.0 2.5 3 0 0 3 3 2 2 G-protein alpha subunit AAA_7 PF12775.7 EIM85959.1 - 0.003 17.1 0.0 0.082 12.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SPARC_Ca_bdg PF10591.9 EIM85959.1 - 0.0038 17.5 1.9 0.15 12.4 0.0 2.7 3 0 0 3 3 2 1 Secreted protein acidic and rich in cysteine Ca binding region AAA_28 PF13521.6 EIM85959.1 - 0.0042 17.3 0.6 4.9 7.4 0.3 2.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EIM85959.1 - 0.0049 16.6 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 EIM85959.1 - 0.0075 16.1 1.6 7.3 6.3 0.1 3.9 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 EIM85959.1 - 0.008 15.4 0.1 0.69 9.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EIM85959.1 - 0.011 15.7 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EIM85959.1 - 0.014 15.0 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIM85959.1 - 0.021 14.0 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 EIM85959.1 - 0.024 14.6 0.0 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 EIM85959.1 - 0.026 14.3 0.0 7.1 6.3 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E MCM PF00493.23 EIM85959.1 - 0.026 13.6 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EIM85959.1 - 0.037 13.4 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EIM85959.1 - 0.04 14.4 0.2 5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EIM85959.1 - 0.05 13.6 0.0 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EIM85959.1 - 0.065 12.5 0.0 12 5.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin EF-hand_8 PF13833.6 EIM85959.1 - 0.067 13.1 1.2 12 5.8 0.0 3.0 3 0 0 3 3 2 0 EF-hand domain pair Ploopntkinase3 PF18751.1 EIM85959.1 - 0.072 13.0 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AIG1 PF04548.16 EIM85959.1 - 0.13 11.5 0.2 0.54 9.6 0.0 2.1 3 0 0 3 3 3 0 AIG1 family cobW PF02492.19 EIM85959.1 - 0.15 11.7 0.1 6.2 6.4 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EIM85959.1 - 0.16 11.7 0.0 32 4.2 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EIM85959.1 - 0.17 11.6 0.1 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain VWA PF00092.28 EIM85960.1 - 6.5e-10 39.5 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EIM85960.1 - 5.8e-05 23.7 0.0 0.00015 22.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 EIM85960.1 - 0.00012 22.0 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A DUF1635 PF07795.11 EIM85960.1 - 0.16 11.8 0.4 0.26 11.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Zn_clus PF00172.18 EIM85961.1 - 0.051 13.7 4.0 0.12 12.5 4.0 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain BDHCT_assoc PF16204.5 EIM85961.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Vpu PF00558.19 EIM85962.1 - 2 8.3 3.7 11 5.9 0.3 2.6 2 0 0 2 2 2 0 Vpu protein Adaptin_binding PF10199.9 EIM85963.1 - 1.2e-07 32.4 0.1 4e-06 27.4 0.1 2.5 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SOG2 PF10428.9 EIM85963.1 - 1.9 7.6 7.2 3.2 6.9 7.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CDC37_N PF03234.14 EIM85964.1 - 1.4e-40 139.1 3.1 2.1e-40 138.6 0.1 2.5 1 1 1 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EIM85964.1 - 6.3e-32 110.0 0.0 2.7e-31 107.9 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EIM85964.1 - 2.2e-17 63.0 3.8 2.2e-17 63.0 3.8 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain SRF-TF PF00319.18 EIM85966.1 - 6e-21 73.7 0.1 8.8e-21 73.1 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Methyltransf_25 PF13649.6 EIM85967.1 - 1.1e-17 64.6 0.0 5.6e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM85967.1 - 4.2e-14 53.0 0.0 1.3e-13 51.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM85967.1 - 2.7e-10 40.3 0.0 5.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM85967.1 - 9.6e-09 35.9 0.0 2.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM85967.1 - 5.7e-08 32.4 0.0 9.1e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EIM85967.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EIM85967.1 - 0.003 17.7 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 EIM85967.1 - 0.0073 14.9 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 EIM85967.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 EIM85967.1 - 0.25 10.9 0.0 0.44 10.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Epimerase PF01370.21 EIM85968.1 - 1.2e-34 119.8 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM85968.1 - 5.6e-32 111.5 0.0 7.7e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Exostosin PF03016.15 EIM85968.1 - 6.4e-30 104.4 0.0 1.3e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 Exostosin family 3Beta_HSD PF01073.19 EIM85968.1 - 1.4e-19 70.2 0.0 1.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EIM85968.1 - 2.8e-12 46.4 0.0 4.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIM85968.1 - 2.2e-11 43.4 0.0 7.6e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EIM85968.1 - 0.00011 21.5 0.3 0.053 12.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EIM85968.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF5488 PF17590.2 EIM85968.1 - 0.17 11.7 1.4 0.41 10.4 1.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5488) MBOAT_2 PF13813.6 EIM85969.1 - 8.7e-15 54.8 1.0 8.7e-15 54.8 1.0 2.1 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family ADH_zinc_N PF00107.26 EIM85970.1 - 1.6e-13 50.7 0.0 3.2e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM85970.1 - 1.1e-06 28.5 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM85970.1 - 0.0013 19.8 0.0 0.002 19.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cyclin_N PF00134.23 EIM85971.1 - 4.1e-10 39.5 0.1 2e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain LPD22 PF18834.1 EIM85971.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 adh_short PF00106.25 EIM85972.1 - 3.5e-24 85.4 0.0 7.8e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM85972.1 - 5.3e-12 45.8 0.0 2.2e-09 37.2 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM85972.1 - 0.0002 21.3 0.1 0.00032 20.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM85972.1 - 0.067 12.6 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Epimerase PF01370.21 EIM85973.1 - 2.8e-16 59.7 0.0 3.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM85973.1 - 1.4e-14 53.7 0.0 2.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM85973.1 - 7.5e-10 38.4 0.1 1.4e-08 34.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIM85973.1 - 9.3e-10 38.4 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM85973.1 - 3.7e-08 33.5 1.1 8.1e-08 32.4 0.5 1.9 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EIM85973.1 - 3.5e-05 23.5 0.1 6.3e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EIM85973.1 - 0.0075 15.7 1.6 0.012 15.1 0.1 2.0 3 0 0 3 3 3 1 short chain dehydrogenase Mito_carr PF00153.27 EIM85975.1 - 9.1e-40 134.5 3.9 4.3e-14 52.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Heme_oxygenase PF01126.20 EIM85976.1 - 1e-30 107.1 0.0 1.4e-19 70.7 0.0 3.0 2 1 0 2 2 2 2 Heme oxygenase AMP-binding PF00501.28 EIM85977.1 - 8e-82 275.1 0.0 1.4e-81 274.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme FUSC_2 PF13515.6 EIM85977.1 - 1.7 8.8 17.4 0.13 12.3 5.0 3.3 3 1 0 3 3 3 0 Fusaric acid resistance protein-like Sod_Cu PF00080.20 EIM85978.1 - 1.9e-49 167.5 3.0 2.4e-49 167.2 3.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) BppL_N PF18338.1 EIM85978.1 - 0.00076 19.1 2.0 0.95 9.3 0.3 3.8 3 0 0 3 3 3 2 Lower baseplate protein N-terminal domain CHRD PF07452.12 EIM85978.1 - 0.016 16.2 1.8 0.062 14.3 1.0 1.9 1 1 1 2 2 2 0 CHRD domain AARP2CN PF08142.12 EIM85978.1 - 0.15 12.2 0.3 0.31 11.1 0.1 1.6 2 0 0 2 2 2 0 AARP2CN (NUC121) domain Lipase_GDSL PF00657.22 EIM85979.1 - 0.11 12.4 0.6 0.34 10.9 0.6 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Motile_Sperm PF00635.26 EIM85980.1 - 2.3e-26 91.8 0.2 4.5e-26 90.8 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.8 EIM85980.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF756 PF05506.12 EIM85980.1 - 0.13 13.2 0.0 0.42 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF756) Retinal PF15449.6 EIM85980.1 - 3.3 5.4 12.1 3.7 5.2 12.1 1.1 1 0 0 1 1 1 0 Retinal protein Pkinase PF00069.25 EIM85981.1 - 4.6e-71 239.3 0.0 5.8e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM85981.1 - 2.5e-30 105.7 0.0 3.5e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EIM85981.1 - 3.8e-11 43.5 0.7 3.8e-11 43.5 0.7 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EIM85981.1 - 1.4e-06 27.5 0.2 2.3e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIM85981.1 - 2.6e-05 23.7 0.0 8.1e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EIM85981.1 - 0.0042 16.7 0.0 0.56 9.8 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIM85981.1 - 0.031 13.6 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM85981.1 - 0.032 14.2 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family GST_N_2 PF13409.6 EIM85982.1 - 1.3e-09 38.2 0.0 2.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM85982.1 - 5.7e-09 36.3 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM85982.1 - 5.4e-06 26.3 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM85982.1 - 0.0065 16.6 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EIM85982.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SOG2 PF10428.9 EIM85984.1 - 0.055 12.7 16.6 0.064 12.4 16.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 EIM85985.1 - 3e-41 141.5 32.6 3e-41 141.5 32.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM85985.1 - 1.8e-10 40.3 7.6 1.8e-10 40.3 7.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter PH PF00169.29 EIM85986.1 - 0.00012 22.5 0.3 0.00026 21.5 0.3 1.4 1 0 0 1 1 1 1 PH domain RA PF00788.23 EIM85986.1 - 0.051 14.2 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain WD40_like PF17005.5 EIM85987.1 - 0.018 14.4 0.1 0.45 9.8 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain Nup160 PF11715.8 EIM85987.1 - 0.038 12.6 0.0 0.11 11.1 0.0 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PilM PF07419.12 EIM85987.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 PilM WD40 PF00400.32 EIM85987.1 - 1.1 10.2 3.7 30 5.7 0.0 3.9 4 1 0 4 4 4 0 WD domain, G-beta repeat Homeodomain PF00046.29 EIM85988.1 - 1.9e-05 24.4 0.4 3.5e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 Homeodomain Epiglycanin_C PF14654.6 EIM85989.1 - 0.37 10.9 2.2 1.1 9.4 0.4 2.4 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region MIP PF00230.20 EIM85990.1 - 1.9e-06 27.8 0.1 2.4e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 EIM85991.1 - 1.9e-48 165.2 9.9 2.2e-48 165.0 9.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1418 PF07214.12 EIM85991.1 - 0.03 14.2 0.9 0.075 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) GCFC PF07842.12 EIM85992.1 - 0.0001 22.0 0.0 0.0018 17.9 0.0 2.3 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein ATG16 PF08614.11 EIM85992.1 - 0.048 13.9 10.3 0.082 13.1 8.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-K PF11802.8 EIM85992.1 - 0.06 12.9 2.8 0.13 11.9 2.8 1.5 1 0 0 1 1 1 0 Centromere-associated protein K DUF349 PF03993.12 EIM85992.1 - 2.2 8.7 7.9 4.9 7.5 3.3 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Spc7 PF08317.11 EIM85992.1 - 4.4 6.1 11.0 3.3 6.5 2.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Rad60-SLD PF11976.8 EIM85993.1 - 1.9e-08 34.0 0.1 1.3e-06 28.2 0.2 3.0 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like mRNA_triPase PF02940.15 EIM85994.1 - 2e-51 174.8 0.0 2.3e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Zip PF02535.22 EIM85995.1 - 1.1e-32 113.5 2.8 1.6e-32 113.1 2.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PhyH PF05721.13 EIM85996.1 - 0.00059 20.1 0.1 0.23 11.7 0.0 2.7 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) DUF4813 PF16072.5 EIM85996.1 - 0.11 12.2 0.9 0.16 11.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Mit_KHE1 PF10173.9 EIM85997.1 - 4.3e-49 167.2 0.2 5.7e-49 166.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related F-box-like PF12937.7 EIM85999.1 - 9.3e-07 28.7 0.7 3.3e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like GREB1 PF15782.5 EIM86001.1 - 7 3.6 11.8 10 3.1 11.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM223 PF14640.6 EIM86002.1 - 4.7e-05 23.6 0.0 6.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 Glyco_hydro_43 PF04616.14 EIM86003.1 - 2e-29 102.8 0.6 2.4e-29 102.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CH PF00307.31 EIM86004.1 - 2.1e-43 146.9 0.0 5e-26 91.0 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EIM86004.1 - 3.4e-18 65.5 0.1 2.4e-17 62.8 0.0 2.5 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EIM86004.1 - 4.4e-12 45.7 0.2 1.6e-09 37.4 0.1 2.6 2 0 0 2 2 2 1 CAMSAP CH domain Vps5 PF09325.10 EIM86004.1 - 0.00067 19.3 0.1 0.1 12.1 0.0 2.5 2 0 0 2 2 2 1 Vps5 C terminal like EF-hand_6 PF13405.6 EIM86004.1 - 0.0017 18.1 0.0 0.0081 16.0 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain Seryl_tRNA_N PF02403.22 EIM86004.1 - 0.0029 17.8 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 EIM86004.1 - 0.0041 16.1 1.6 0.0081 15.1 1.2 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein EF-hand_1 PF00036.32 EIM86004.1 - 0.014 14.9 0.1 0.09 12.4 0.0 2.4 2 0 0 2 2 2 0 EF hand TolA_bind_tri PF16331.5 EIM86004.1 - 0.015 15.4 0.7 0.073 13.1 0.7 2.2 1 1 0 1 1 1 0 TolA binding protein trimerisation NPV_P10 PF05531.12 EIM86004.1 - 0.022 15.2 0.6 5 7.7 0.2 3.6 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EIM86004.1 - 0.026 14.7 1.5 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EIM86004.1 - 0.027 14.5 0.2 0.027 14.5 0.2 2.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tektin PF03148.14 EIM86004.1 - 0.028 13.2 0.7 0.048 12.4 0.7 1.3 1 0 0 1 1 1 0 Tektin family CENP-F_leu_zip PF10473.9 EIM86004.1 - 0.046 13.8 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EIM86004.1 - 0.047 12.6 0.8 0.079 11.8 0.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like COG2 PF06148.11 EIM86004.1 - 0.064 13.3 0.7 0.3 11.2 0.1 2.3 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MIF4G PF02854.19 EIM86004.1 - 0.078 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 MIF4G domain DUF1664 PF07889.12 EIM86004.1 - 0.09 12.8 1.1 0.45 10.5 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 EIM86004.1 - 0.17 12.4 3.2 19 5.8 0.2 3.2 1 1 3 4 4 4 0 Spectrin repeat Exonuc_VII_L PF02601.15 EIM86004.1 - 0.82 9.2 3.6 2 7.9 3.6 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.6 EIM86004.1 - 3.9 7.5 6.2 1.8 8.6 2.2 2.4 2 1 0 2 2 2 0 FlxA-like protein Cofilin_ADF PF00241.20 EIM86005.1 - 6.7e-43 145.3 0.5 7.5e-43 145.2 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Porin_3 PF01459.22 EIM86007.1 - 2.1e-75 253.7 1.0 2.3e-75 253.5 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rhodanese PF00581.20 EIM86008.1 - 8.9e-11 42.3 0.0 1.1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Oxidored_nitro PF00148.19 EIM86008.1 - 0.16 10.7 0.0 0.19 10.4 0.0 1.0 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase zf-CRD PF17979.1 EIM86010.1 - 1.3e-09 38.4 0.0 1.3e-09 38.4 0.0 2.4 2 1 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 EIM86010.1 - 1.8e-05 24.5 11.4 1.8e-05 24.5 11.4 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM86010.1 - 4.7e-05 23.6 12.2 4.7e-05 23.6 12.2 3.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 EIM86010.1 - 0.00022 21.0 9.3 0.00022 21.0 9.3 3.8 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM86010.1 - 0.00055 19.7 10.7 0.00055 19.7 10.7 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EIM86010.1 - 0.00068 19.4 7.0 0.00068 19.4 7.0 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EIM86010.1 - 0.01 15.8 10.6 0.01 15.8 10.6 3.2 3 0 0 3 3 3 0 zinc-RING finger domain SAPS PF04499.15 EIM86011.1 - 1.2 7.9 4.5 1.2 7.8 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 EIM86011.1 - 8 4.4 7.7 7.5 4.6 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF908 PF06012.12 EIM86011.1 - 9.6 5.5 7.0 11 5.3 7.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF202 PF02656.15 EIM86012.1 - 1.3e-17 64.0 2.9 1.3e-17 64.0 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CrgA PF06781.12 EIM86012.1 - 0.057 13.5 0.4 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Cell division protein CrgA Kelch_1 PF01344.25 EIM86013.1 - 1.5e-20 72.4 1.2 2.5e-06 27.0 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 EIM86013.1 - 3e-19 68.8 4.2 7.3e-05 22.7 0.2 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EIM86013.1 - 3.8e-19 68.5 5.3 9.8e-09 35.3 0.0 5.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EIM86013.1 - 3.6e-17 62.0 6.1 0.0011 19.2 0.1 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EIM86013.1 - 1e-15 57.0 7.8 0.0004 20.3 0.1 5.4 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EIM86013.1 - 1.4e-15 56.9 1.1 0.00031 20.7 0.1 4.1 4 0 0 4 4 4 3 Kelch motif Putative_PNPOx PF01243.20 EIM86014.1 - 6e-23 80.8 0.0 9.8e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EIM86014.1 - 1.2e-18 66.9 1.5 2.2e-18 66.0 1.5 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 EIM86014.1 - 6.7e-06 26.6 0.0 1.2e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EIM86014.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Glycolytic PF00274.19 EIM86015.1 - 1.7e-65 221.1 0.0 2e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Metal_resist PF13801.6 EIM86016.1 - 0.16 12.2 0.4 0.26 11.5 0.0 1.5 2 0 0 2 2 2 0 Heavy-metal resistance Linker_histone PF00538.19 EIM86017.1 - 1.4e-07 31.8 0.0 2.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family FKBP_C PF00254.28 EIM86019.1 - 9.4e-31 106.0 0.0 1.1e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-MYND PF01753.18 EIM86021.1 - 0.095 12.8 1.5 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 MYND finger DUF2256 PF10013.9 EIM86021.1 - 2 8.6 3.4 29 4.9 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) RNase_H PF00075.24 EIM86022.1 - 0.12 12.6 0.8 0.2 11.9 0.8 1.4 1 0 0 1 1 1 0 RNase H zf-C2H2_12 PF18658.1 EIM86022.1 - 0.92 9.1 2.2 0.52 9.9 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger C2H2-type Sec1 PF00995.23 EIM86024.1 - 1.1e-78 266.0 0.0 1.3e-78 265.7 0.0 1.1 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.12 EIM86025.1 - 4.4e-80 268.7 2.1 5.7e-80 268.3 1.7 1.4 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EIM86025.1 - 9.8e-26 89.9 1.1 1.9e-25 89.0 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CHAT PF12770.7 EIM86026.1 - 3.3e-23 82.5 0.2 3.8e-23 82.3 0.2 1.0 1 0 0 1 1 1 1 CHAT domain SelB-wing_2 PF09106.11 EIM86026.1 - 0.018 15.2 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix CENP-F_leu_zip PF10473.9 EIM86027.1 - 0.019 15.0 9.3 0.034 14.2 5.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 EIM86027.1 - 0.025 14.6 0.6 0.025 14.6 0.6 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ERM PF00769.19 EIM86027.1 - 0.49 10.2 16.6 0.0099 15.7 9.6 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FAM184 PF15665.5 EIM86027.1 - 0.63 9.8 17.7 3.5 7.4 6.9 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 EIM86027.1 - 0.87 9.7 20.4 13 5.9 20.4 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EIM86027.1 - 3.3 8.0 11.4 4.3 7.6 7.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 EIM86027.1 - 8.5 6.6 18.6 75 3.5 18.6 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 EIM86027.1 - 9.3 5.5 20.0 15 4.8 18.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2985 PF11204.8 EIM86028.1 - 1.4e-28 98.8 1.3 2.4e-28 98.1 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SCAMP PF04144.13 EIM86029.1 - 0.0063 16.8 5.5 0.0063 16.8 5.5 2.6 1 1 2 3 3 3 1 SCAMP family COX14 PF14880.6 EIM86029.1 - 0.079 12.8 0.7 0.25 11.2 0.7 1.9 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PMP1_2 PF08114.11 EIM86029.1 - 2.2 8.1 5.3 4.5 7.1 0.1 3.3 3 0 0 3 3 3 0 ATPase proteolipid family DLH PF01738.18 EIM86030.1 - 1.6e-21 76.9 0.0 2.6e-21 76.2 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EIM86030.1 - 0.00011 22.0 0.0 0.023 14.3 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM86030.1 - 0.0086 16.7 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CRAL_TRIO PF00650.20 EIM86031.1 - 6.6e-27 94.2 0.0 9.3e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIM86031.1 - 4.7e-14 52.3 0.4 8.8e-14 51.4 0.4 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EIM86031.1 - 0.0043 17.2 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Amidohydro_1 PF01979.20 EIM86032.1 - 0.0028 17.0 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family HEAT_2 PF13646.6 EIM86033.1 - 3.1e-37 126.8 0.7 4.6e-16 59.0 0.1 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 EIM86033.1 - 1e-22 78.5 0.0 0.0015 19.0 0.0 6.4 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 EIM86033.1 - 3.1e-13 48.7 0.3 0.0088 16.2 0.0 4.9 4 0 0 4 4 4 3 HEAT repeat Arm PF00514.23 EIM86033.1 - 2.5e-06 27.3 0.1 0.014 15.4 0.1 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EIM86033.1 - 0.00063 20.2 4.2 1.4 9.5 0.1 5.1 3 2 1 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 EIM86033.1 - 0.044 13.8 0.0 12 5.9 0.0 3.3 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RL10P_insert PF17777.1 EIM86034.1 - 1.6e-22 79.3 0.0 2.9e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EIM86034.1 - 1.5e-21 76.4 0.0 2.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Cu-oxidase_3 PF07732.15 EIM86036.1 - 7e-34 116.4 1.4 2.7e-31 108.0 0.2 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EIM86036.1 - 2.9e-23 82.7 0.3 1.9e-22 80.1 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM86036.1 - 3e-23 82.1 5.5 9.1e-20 70.8 0.3 3.7 3 2 0 3 3 3 2 Multicopper oxidase DUF3324 PF11797.8 EIM86036.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) Acetyltransf_3 PF13302.7 EIM86037.1 - 5.5e-21 75.7 0.0 7e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM86037.1 - 3.8e-15 56.1 0.0 5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EIM86037.1 - 2.6e-06 27.6 0.0 3.4e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM86037.1 - 4.8e-05 23.3 0.0 6.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM86037.1 - 6.2e-05 23.3 0.1 9.5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EIM86037.1 - 0.0001 22.0 0.0 0.00028 20.6 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM86037.1 - 0.0068 16.3 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Cyclase PF04199.13 EIM86037.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative cyclase F-box-like PF12937.7 EIM86038.1 - 1.1e-05 25.2 0.6 2.3e-05 24.2 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM86038.1 - 0.11 12.4 0.2 0.28 11.1 0.2 1.7 1 0 0 1 1 1 0 F-box domain POB3_N PF17292.2 EIM86039.1 - 3.2e-32 110.8 0.2 2.9e-28 98.1 0.1 2.6 2 1 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 EIM86039.1 - 1.7e-24 85.5 0.3 4.3e-24 84.2 0.0 1.9 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EIM86039.1 - 5e-20 71.7 0.0 2e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CHAT PF12770.7 EIM86040.1 - 1.2e-32 113.4 0.0 2.5e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM86040.1 - 6e-05 22.8 1.9 0.23 11.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM86040.1 - 0.26 11.6 2.9 36 4.8 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat PP2C PF00481.21 EIM86041.1 - 6.4e-81 271.8 0.0 1.5e-80 270.5 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EIM86041.1 - 0.036 13.7 0.0 0.081 12.5 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C Glyco_hydro_71 PF03659.14 EIM86043.1 - 2e-127 425.1 10.0 2.5e-127 424.8 10.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CS PF04969.16 EIM86044.1 - 8.4e-10 39.5 0.0 2.9e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 CS domain Sugar_tr PF00083.24 EIM86045.1 - 5.4e-90 302.4 22.0 6.2e-90 302.2 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM86045.1 - 1.3e-34 119.6 47.0 7e-32 110.7 25.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM86045.1 - 4.1e-11 42.0 1.4 4.1e-11 42.0 1.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BUD22 PF09073.10 EIM86046.1 - 4.8e-76 256.8 29.6 7.5e-76 256.2 29.6 1.3 1 0 0 1 1 1 1 BUD22 DUF4355 PF14265.6 EIM86046.1 - 0.13 12.5 9.4 0.55 10.5 9.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TFCD_C PF12612.8 EIM86047.1 - 1.4e-39 135.9 0.0 1e-38 133.1 0.0 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 EIM86047.1 - 0.00038 20.8 1.6 0.88 10.0 0.0 4.6 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.22 EIM86047.1 - 0.0031 17.6 13.6 0.18 12.1 0.1 6.7 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 EIM86047.1 - 0.011 14.3 3.8 15 4.0 0.0 4.6 4 1 1 5 5 5 0 Adaptin N terminal region HEAT_EZ PF13513.6 EIM86047.1 - 0.017 15.6 2.0 25 5.5 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 EIM86047.1 - 0.018 15.2 0.1 2.1 8.6 0.0 3.4 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EIM86047.1 - 0.049 13.7 0.0 0.56 10.2 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ATP-synt_ab PF00006.25 EIM86048.1 - 8.1e-68 228.2 0.0 1.1e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EIM86048.1 - 1.5e-12 47.8 0.5 2.6e-12 47.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tcp11 PF05794.13 EIM86050.1 - 1.3e-61 209.1 21.1 6.8e-39 134.2 7.5 3.8 2 2 0 2 2 2 2 T-complex protein 11 F-box-like PF12937.7 EIM86051.1 - 2.2e-07 30.7 0.4 1.9e-06 27.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like AA_permease PF00324.21 EIM86052.1 - 8.2e-115 384.1 39.2 1e-114 383.8 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM86052.1 - 9.9e-34 116.9 47.3 1.2e-33 116.6 47.3 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 EIM86052.1 - 0.11 13.2 0.3 0.11 13.2 0.3 4.3 4 0 0 4 4 4 0 PrgI family protein G-patch PF01585.23 EIM86053.1 - 9.7e-06 25.4 0.1 0.00014 21.7 0.2 2.4 2 0 0 2 2 2 1 G-patch domain HHV6-IE PF03753.13 EIM86053.1 - 4.2 4.7 7.3 5.5 4.3 7.3 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein F-box-like PF12937.7 EIM86054.1 - 4.7e-12 45.6 0.8 1.4e-11 44.1 0.1 2.3 2 0 0 2 2 2 1 F-box-like CLZ PF16526.5 EIM86054.1 - 0.043 14.2 0.1 0.098 13.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels F-box PF00646.33 EIM86054.1 - 5.3 7.1 7.3 0.47 10.4 0.3 3.1 3 1 0 3 3 3 0 F-box domain PQ-loop PF04193.14 EIM86055.1 - 1.3e-34 117.8 12.5 6e-21 74.0 1.8 3.2 2 1 1 3 3 3 2 PQ loop repeat DUF1673 PF07895.11 EIM86055.1 - 0.11 12.2 3.6 0.26 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Band_7 PF01145.25 EIM86056.1 - 1.1e-21 77.6 1.0 1.5e-21 77.2 1.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_V PF00488.21 EIM86057.1 - 2.2e-42 145.3 0.0 7.3e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIM86057.1 - 1.4e-30 107.0 1.0 8e-30 104.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EIM86057.1 - 0.0099 16.2 0.2 0.037 14.4 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV F-box-like PF12937.7 EIM86058.1 - 7.9e-07 28.9 4.1 7.9e-07 28.9 4.1 3.2 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 EIM86058.1 - 0.073 13.0 6.2 0.77 9.7 0.8 3.4 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.7 EIM86058.1 - 0.13 12.8 1.3 8.8 6.9 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Thi4 PF01946.17 EIM86059.1 - 1.1e-100 335.7 0.2 1.3e-100 335.4 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EIM86059.1 - 9.9e-09 35.2 0.9 4.9e-08 33.0 0.5 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM86059.1 - 2e-06 27.9 0.1 5.2e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM86059.1 - 2.2e-06 27.2 0.0 3.1e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM86059.1 - 1e-05 24.8 0.4 3.4e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EIM86059.1 - 4.3e-05 23.5 1.9 0.0013 18.7 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIM86059.1 - 9.7e-05 21.6 2.3 0.00096 18.3 0.5 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIM86059.1 - 0.00096 17.9 0.4 0.0018 17.1 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EIM86059.1 - 0.034 13.2 0.1 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EIM86059.1 - 0.044 13.1 0.1 0.044 13.1 0.1 1.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM86059.1 - 0.052 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM86059.1 - 0.13 11.1 0.2 0.2 10.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DHHC PF01529.20 EIM86060.1 - 3.4e-30 104.9 11.9 7.7e-30 103.7 11.9 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase FAM70 PF14967.6 EIM86060.1 - 0.023 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 FAM70 protein CM_2 PF01817.21 EIM86061.1 - 1.6e-05 25.1 0.0 0.055 13.8 0.0 2.7 2 0 0 2 2 2 2 Chorismate mutase type II DNase_NucA_NucB PF14040.6 EIM86062.1 - 3e-19 69.5 1.6 2.4e-18 66.6 1.6 2.1 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB DNase_NucA_NucB PF14040.6 EIM86063.1 - 2.7e-21 76.1 2.1 4e-21 75.5 2.1 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DNase_NucA_NucB PF14040.6 EIM86065.1 - 1e-20 74.2 3.9 2.1e-20 73.2 3.9 1.5 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB SMI1_KNR4 PF09346.10 EIM86066.1 - 3e-07 30.9 0.0 6.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 EIM86066.1 - 2.7e-05 24.6 0.1 5.8e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 EIM86066.1 - 0.00011 21.9 0.0 0.00049 19.8 0.0 2.0 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall ORC5_C PF14630.6 EIM86066.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DNase_NucA_NucB PF14040.6 EIM86067.1 - 5e-19 68.8 1.3 7e-19 68.3 1.3 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Stealth_CR2 PF11380.8 EIM86068.1 - 0.026 14.7 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 Epimerase PF01370.21 EIM86069.1 - 9.2e-16 58.0 0.0 1.2e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM86069.1 - 6e-13 48.9 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM86069.1 - 1.1e-06 27.8 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM86069.1 - 6.2e-05 22.3 0.0 0.045 12.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EIM86069.1 - 6.2e-05 22.2 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EIM86069.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 EIM86069.1 - 0.093 12.6 0.9 0.72 9.7 0.9 2.2 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 EIM86069.1 - 0.16 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding LacAB_rpiB PF02502.18 EIM86070.1 - 8.1e-45 152.2 0.0 9.4e-45 152.0 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.6 EIM86070.1 - 0.032 14.2 0.5 0.092 12.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) KptA_kDCL PF18176.1 EIM86070.1 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 2 0 0 2 2 2 0 KptA in kinetoplastid DICER domain DUF2773 PF10971.8 EIM86070.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) F_bP_aldolase PF01116.20 EIM86071.1 - 5.4e-73 245.9 0.0 6.2e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.16 EIM86072.1 - 1.8e-33 115.9 27.5 1.8e-33 115.9 27.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EIM86072.1 - 0.004 15.6 0.8 0.004 15.6 0.8 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector UPF0715 PF17094.5 EIM86072.1 - 0.043 14.4 0.5 0.043 14.4 0.5 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0715) MRAP PF15183.6 EIM86072.1 - 0.18 11.8 1.0 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family E1-E2_ATPase PF00122.20 EIM86072.1 - 7.3 6.1 6.3 0.74 9.3 1.2 2.0 2 0 0 2 2 2 0 E1-E2 ATPase Fungal_trans PF04082.18 EIM86073.1 - 2e-26 92.6 0.0 3.4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86073.1 - 1.8e-05 24.7 12.4 3.5e-05 23.8 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.17 EIM86074.1 - 1.4e-95 319.8 0.4 1.8e-95 319.4 0.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EIM86074.1 - 2.1e-40 138.5 2.1 3.5e-40 137.7 2.1 1.4 1 0 0 1 1 1 1 DAK2 domain SIKE PF05769.11 EIM86075.1 - 1.6e-05 24.9 12.8 0.0014 18.6 9.4 2.4 2 1 0 2 2 2 2 SIKE family Nsp1_C PF05064.13 EIM86075.1 - 0.01 15.7 0.5 0.01 15.7 0.5 1.9 2 1 0 2 2 2 1 Nsp1-like C-terminal region Cnn_1N PF07989.11 EIM86075.1 - 0.21 11.8 6.5 0.36 11.0 0.9 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 EIM86075.1 - 0.47 10.8 7.1 0.92 9.8 7.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RasGAP_C PF03836.15 EIM86075.1 - 0.71 10.0 7.1 0.14 12.3 3.2 1.8 2 0 0 2 2 2 0 RasGAP C-terminus DUF3920 PF13058.6 EIM86075.1 - 1.5 9.1 4.6 0.44 10.8 0.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3920) TSC22 PF01166.18 EIM86075.1 - 3.6 8.0 6.0 6.7 7.1 0.1 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EIM86075.1 - 6.2 7.0 8.0 0.89 9.7 0.7 2.6 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 EIM86075.1 - 9.4 6.1 11.6 0.2 11.5 1.7 3.0 4 0 0 4 4 4 0 Septum formation initiator ABM PF03992.16 EIM86076.1 - 7.6e-09 35.6 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FAD_binding_2 PF00890.24 EIM86077.1 - 1.5e-44 152.8 0.6 9.1e-39 133.7 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EIM86077.1 - 1.3e-05 24.8 0.2 8.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EIM86077.1 - 0.00015 21.5 5.5 0.00015 21.5 5.5 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM86077.1 - 0.00023 20.5 1.4 0.16 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM86077.1 - 0.00048 19.3 4.6 0.014 14.5 0.1 3.2 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM86077.1 - 0.0032 17.7 0.4 0.0032 17.7 0.4 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIM86077.1 - 0.0034 16.1 3.6 0.23 10.1 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein adh_short PF00106.25 EIM86078.1 - 6.1e-40 136.8 0.8 1.2e-39 135.9 0.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM86078.1 - 2.8e-39 135.1 4.8 1.1e-37 129.9 4.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM86078.1 - 2e-09 37.6 0.6 4.5e-09 36.5 0.6 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EIM86078.1 - 0.0074 16.5 0.8 0.013 15.7 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 EIM86078.1 - 0.011 16.2 0.1 0.11 13.1 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EIM86078.1 - 0.022 14.8 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EIM86078.1 - 0.068 12.6 0.2 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EIM86078.1 - 0.12 13.0 1.1 0.19 12.4 0.3 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.22 EIM86079.1 - 2.3e-56 187.5 1.5 4.8e-18 64.7 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM86079.1 - 3.9e-16 58.7 0.0 0.00022 21.0 0.0 4.5 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_7 PF16367.5 EIM86079.1 - 1.2e-06 28.5 0.1 0.73 10.0 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EIM86079.1 - 3e-06 27.1 0.0 0.24 11.4 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EIM86079.1 - 1.4e-05 25.1 0.2 3.9 7.6 0.0 5.1 4 0 0 4 4 4 1 RNA binding motif TPR_19 PF14559.6 EIM86079.1 - 0.0018 18.8 0.8 0.0018 18.8 0.8 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM86079.1 - 0.014 15.6 0.3 0.086 13.1 0.3 2.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EIM86079.1 - 0.02 15.5 3.6 0.02 15.5 3.6 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BslA PF17735.1 EIM86079.1 - 0.09 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Biofilm surface layer A TPR_14 PF13428.6 EIM86079.1 - 8.2 7.5 27.6 0.11 13.3 1.6 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat FtsX PF02687.21 EIM86080.1 - 0.33 11.4 0.1 0.33 11.4 0.1 2.6 1 1 1 2 2 2 0 FtsX-like permease family Basic PF01586.16 EIM86083.1 - 0.013 16.6 1.8 0.93 10.7 0.8 3.4 2 0 0 2 2 2 0 Myogenic Basic domain PLDc_2 PF13091.6 EIM86084.1 - 1.9e-13 50.5 0.0 1e-06 28.6 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EIM86084.1 - 5.8e-13 48.8 0.1 1.7e-10 40.8 0.2 3.2 2 1 0 2 2 2 1 PX domain PLDc PF00614.22 EIM86084.1 - 1.3e-12 47.3 1.0 7.4e-05 22.8 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Rho_N PF07498.12 EIM86085.1 - 0.0055 16.6 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 EIM86085.1 - 0.0066 16.2 0.9 0.0097 15.6 0.1 1.7 2 0 0 2 2 2 1 SAP domain PROCN PF08083.11 EIM86086.1 - 2.2e-231 767.7 10.5 3.2e-231 767.1 9.0 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EIM86086.1 - 1.4e-126 420.7 0.5 4e-126 419.3 0.4 1.8 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EIM86086.1 - 1.2e-87 291.9 2.3 1.2e-87 291.9 2.3 2.2 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EIM86086.1 - 1.7e-84 281.3 2.2 1.7e-84 281.3 2.2 3.0 4 0 0 4 4 4 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EIM86086.1 - 2e-73 244.8 0.1 4e-73 243.8 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EIM86086.1 - 3.4e-46 155.5 0.4 7.2e-46 154.5 0.4 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EIM86086.1 - 7.6e-41 138.9 0.0 1.6e-40 137.8 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 EIM86086.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Corona_5a PF06336.11 EIM86086.1 - 0.13 12.2 0.3 0.51 10.4 0.3 2.0 1 0 0 1 1 1 0 Coronavirus 5a protein MATH PF00917.26 EIM86087.1 - 9.3e-07 29.0 0.4 1.9e-06 28.0 0.4 1.4 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 EIM86087.1 - 2.8e-05 24.3 0.0 0.16 12.2 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain GRASP55_65 PF04495.14 EIM86088.1 - 6.3e-52 175.5 0.0 1.4e-36 125.9 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EIM86088.1 - 0.0019 18.5 0.0 0.84 10.0 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EIM86088.1 - 0.02 14.7 0.0 0.064 13.1 0.0 1.8 2 0 0 2 2 2 0 PDZ domain PPR_3 PF13812.6 EIM86089.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain ERAP1_C PF11838.8 EIM86089.1 - 0.04 13.5 0.1 3 7.3 0.0 2.7 3 1 0 3 3 3 0 ERAP1-like C-terminal domain Fungal_trans PF04082.18 EIM86090.1 - 5.3e-19 68.3 0.1 8.2e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86090.1 - 6.8e-07 29.3 9.3 1.2e-06 28.5 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.21 EIM86091.1 - 2.6e-32 112.1 0.1 3.3e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 EIM86091.1 - 0.12 12.8 0.2 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding SKN1 PF03935.15 EIM86092.1 - 4.5e-207 688.4 7.6 5.1e-207 688.2 7.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Mur_ligase_M PF08245.12 EIM86093.1 - 2.5e-06 27.6 0.0 9.2e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Methyltransf_32 PF13679.6 EIM86094.1 - 5.2e-23 81.8 0.0 2.9e-21 76.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM86094.1 - 0.017 15.8 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EIM86094.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EIM86094.1 - 0.052 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86094.1 - 0.12 13.1 0.0 0.39 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Endonuc-FokI_C PF09254.11 EIM86094.1 - 0.16 11.2 0.1 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal ORC6 PF05460.13 EIM86094.1 - 0.17 11.1 0.7 0.31 10.3 0.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) adh_short PF00106.25 EIM86095.1 - 3e-43 147.6 0.2 3.8e-43 147.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM86095.1 - 1.5e-34 119.6 0.2 1.9e-34 119.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM86095.1 - 0.00072 19.5 0.6 0.001 19.0 0.6 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM86095.1 - 0.023 13.8 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glu_dehyd_C PF16912.5 EIM86095.1 - 0.055 12.9 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus HEM4 PF02602.15 EIM86095.1 - 0.062 12.7 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD 3HCDH_N PF02737.18 EIM86095.1 - 0.074 12.9 1.0 0.096 12.6 0.4 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EIM86096.1 - 2.7e-56 191.0 0.0 4e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EIM86096.1 - 2e-15 55.5 0.0 1.9e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EIM86096.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain OPT PF03169.15 EIM86097.1 - 9.6e-140 467.1 40.4 1.1e-139 466.9 40.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Bac_export_2 PF01312.19 EIM86097.1 - 0.34 10.1 1.0 0.51 9.5 0.1 1.8 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family ADH_zinc_N PF00107.26 EIM86098.1 - 9.4e-24 83.9 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM86098.1 - 4.3e-16 60.2 0.0 6.8e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM86098.1 - 3e-10 40.0 0.0 8e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EIM86098.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase F-box_4 PF15966.5 EIM86099.1 - 0.11 12.3 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 EIM86100.1 - 0.0018 18.1 0.1 0.0051 16.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like PLN_propep PF16485.5 EIM86100.1 - 2.1 8.1 3.7 0.61 9.8 0.2 1.9 3 0 0 3 3 3 0 Protealysin propeptide AhpC-TSA PF00578.21 EIM86101.1 - 4.7e-28 97.6 0.0 6e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIM86101.1 - 5.3e-17 61.9 0.0 7.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EIM86101.1 - 0.00065 19.8 0.0 0.00096 19.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF4031 PF13223.6 EIM86101.1 - 0.0037 17.4 0.1 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4031) E1_dh PF00676.20 EIM86102.1 - 3.6e-87 292.1 0.0 4.3e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Peptidase_C48 PF02902.19 EIM86103.1 - 7.6e-36 124.0 0.4 1.4e-20 74.1 0.1 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SMC_N PF02463.19 EIM86106.1 - 1.3e-28 100.0 0.0 3.8e-28 98.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIM86106.1 - 8.4e-17 62.3 6.4 8.4e-17 62.3 6.4 5.3 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 EIM86106.1 - 8.9e-08 32.3 1.5 0.011 15.5 0.5 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM86106.1 - 1e-05 25.5 13.4 1e-05 25.5 13.4 3.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EIM86106.1 - 0.0009 18.9 0.9 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DMPK_coil PF08826.10 EIM86106.1 - 0.0015 18.6 0.9 0.0015 18.6 0.9 5.5 6 0 0 6 6 6 1 DMPK coiled coil domain like SbcCD_C PF13558.6 EIM86106.1 - 0.0089 16.2 0.0 0.058 13.6 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EIM86106.1 - 0.23 12.0 0.1 0.23 12.0 0.1 5.9 4 2 0 4 4 4 0 ABC transporter Baculo_PEP_C PF04513.12 EIM86106.1 - 4.7 7.3 26.9 12 5.9 6.4 5.9 2 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EIM86106.1 - 5.4 5.8 75.0 2 7.2 16.2 5.2 2 2 2 5 5 5 0 Spc7 kinetochore protein OPT PF03169.15 EIM86107.1 - 4.6e-170 567.3 51.4 5.3e-170 567.1 51.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DIOX_N PF14226.6 EIM86108.1 - 3e-31 108.6 0.0 4.7e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM86108.1 - 6.5e-21 74.7 0.0 1.7e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily OPT PF03169.15 EIM86109.1 - 1.1e-138 463.7 46.6 1.2e-138 463.5 46.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_16 PF00722.21 EIM86110.1 - 1.5e-05 24.6 0.1 2.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 adh_short_C2 PF13561.6 EIM86111.1 - 8.7e-26 90.9 0.0 6.3e-13 48.8 0.0 3.1 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM86111.1 - 9.7e-26 90.4 0.0 8.2e-18 64.6 0.0 3.2 3 0 0 3 3 3 3 short chain dehydrogenase KR PF08659.10 EIM86111.1 - 0.00014 21.8 0.1 0.00028 20.8 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1324 PF07038.11 EIM86111.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) OPT PF03169.15 EIM86112.1 - 3.9e-182 607.1 53.5 4.6e-182 606.9 53.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein KAR9 PF08580.10 EIM86114.1 - 2.4 6.6 18.0 2.8 6.4 18.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Pkinase PF00069.25 EIM86115.1 - 1.8e-70 237.3 0.0 2.9e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86115.1 - 3.1e-49 167.6 0.0 7.8e-49 166.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RICTOR_N PF14664.6 EIM86115.1 - 1e-05 24.8 9.3 0.014 14.4 2.6 2.5 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term Pkinase_fungal PF17667.1 EIM86115.1 - 0.0019 17.1 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIM86115.1 - 0.041 13.2 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Uso1_p115_head PF04869.14 EIM86115.1 - 0.084 12.0 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region DUF4704 PF15787.5 EIM86115.1 - 0.71 9.1 6.7 0.16 11.2 0.2 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4704) Palm_thioest PF02089.15 EIM86116.1 - 0.00072 19.5 0.0 0.0016 18.4 0.0 1.5 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EIM86116.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EIM86116.1 - 0.059 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein SKG6 PF08693.10 EIM86117.1 - 0.034 13.6 0.2 0.093 12.1 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4381 PF14316.6 EIM86117.1 - 0.073 13.3 0.4 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Phage_holin_2_4 PF16082.5 EIM86117.1 - 0.2 11.4 0.2 0.48 10.2 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like zf-Tim10_DDP PF02953.15 EIM86119.1 - 8.1e-20 70.2 7.7 1.1e-19 69.8 7.7 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AAA_8 PF12780.7 EIM86119.1 - 0.066 12.5 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Tam41_Mmp37 PF09139.11 EIM86119.1 - 0.12 11.8 0.1 0.13 11.7 0.1 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DAHP_synth_1 PF00793.20 EIM86120.1 - 5e-95 317.5 0.0 6.3e-95 317.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2188 PF09954.9 EIM86121.1 - 0.078 13.1 0.7 9.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) NifU PF01106.17 EIM86124.1 - 0.0037 17.4 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 NifU-like domain Apt1 PF10351.9 EIM86124.1 - 0.026 13.4 3.5 0.029 13.3 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EIM86124.1 - 0.46 9.0 6.7 0.64 8.5 6.7 1.4 1 0 0 1 1 1 0 Macoilin family Pol_alpha_B_N PF08418.10 EIM86124.1 - 3.8 7.4 8.6 5.3 6.9 8.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SAM_2 PF07647.17 EIM86125.1 - 1.6e-08 34.5 0.1 9e-08 32.1 0.0 2.3 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EIM86125.1 - 0.00091 19.6 0.1 0.0025 18.2 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF1281 PF06924.11 EIM86125.1 - 0.041 13.4 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4508 PF14969.6 EIM86125.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF5643 PF18705.1 EIM86125.1 - 0.32 11.0 0.7 0.8 9.7 0.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5643) tRNA_lig_CPD PF08302.11 EIM86125.1 - 2.4 7.6 3.4 0.92 8.9 0.0 1.8 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Spt20 PF12090.8 EIM86125.1 - 4.2 6.9 5.2 7.4 6.1 5.2 1.3 1 0 0 1 1 1 0 Spt20 family OPT PF03169.15 EIM86127.1 - 1.2e-139 466.8 44.1 1.4e-139 466.6 44.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hydrolase_4 PF12146.8 EIM86128.1 - 1.5e-06 27.7 0.0 6.5e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM86128.1 - 4.2e-05 24.2 0.2 5.9e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 EIM86128.1 - 0.0062 15.7 0.1 0.0092 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 EIM86128.1 - 0.018 14.5 0.3 0.23 10.9 0.3 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EIM86128.1 - 0.046 13.4 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 EIM86128.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 EIM86128.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ribosomal_L1 PF00687.21 EIM86129.1 - 4.2e-52 176.9 5.7 1e-51 175.6 0.0 3.0 3 0 0 3 3 3 2 Ribosomal protein L1p/L10e family Hydrolase_4 PF12146.8 EIM86130.1 - 0.00066 19.0 0.3 0.0016 17.8 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM86130.1 - 0.011 15.3 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM86130.1 - 0.014 14.9 0.1 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.8 EIM86130.1 - 0.015 14.9 0.0 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Peptidase_M64 PF09471.10 EIM86132.1 - 5.8e-25 88.3 0.0 2.8e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 IgA Peptidase M64 RNA_pol_Rpb4 PF03874.16 EIM86135.1 - 1.5e-20 73.8 0.3 2e-20 73.4 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.21 EIM86135.1 - 0.078 13.3 0.0 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Death effector domain Prenyltrans PF00432.21 EIM86136.1 - 2e-22 78.6 19.1 6.2e-07 29.0 1.4 6.0 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Mito_fiss_reg PF05308.11 EIM86136.1 - 2.2 8.3 10.3 4.9 7.2 10.3 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator UcrQ PF02939.16 EIM86137.1 - 0.039 13.9 0.2 0.056 13.4 0.2 1.2 1 0 0 1 1 1 0 UcrQ family Pkinase PF00069.25 EIM86138.1 - 6.3e-08 32.3 0.0 3.6e-06 26.5 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86138.1 - 0.042 13.1 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 EIM86139.1 - 7.6e-09 35.3 0.0 1e-06 28.3 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86139.1 - 0.015 14.6 0.0 0.42 9.8 0.0 2.3 2 1 1 3 3 3 0 Protein tyrosine kinase Pkinase PF00069.25 EIM86142.1 - 8.9e-08 31.8 0.0 5.7e-06 25.9 0.0 2.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86142.1 - 0.21 10.9 0.0 0.79 9.0 0.0 2.0 2 1 1 3 3 3 0 Protein tyrosine kinase Pkinase PF00069.25 EIM86143.1 - 3e-09 36.7 0.0 1.8e-06 27.5 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86143.1 - 0.002 17.5 0.1 0.019 14.2 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EIM86144.1 - 8.5e-08 31.9 0.0 2.4e-06 27.1 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain THOC7 PF05615.13 EIM86145.1 - 0.12 12.6 15.0 0.22 11.8 14.3 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Nup88 PF10168.9 EIM86145.1 - 0.28 8.9 8.6 0.39 8.5 8.6 1.1 1 0 0 1 1 1 0 Nuclear pore component HALZ PF02183.18 EIM86145.1 - 0.35 11.1 8.4 7.1 6.9 0.2 2.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.6 EIM86145.1 - 1.2 9.3 7.0 0.58 10.3 2.6 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain APG6_N PF17675.1 EIM86145.1 - 5.3 7.6 22.8 63 4.1 22.8 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1639 PF07797.14 EIM86146.1 - 0.03 14.3 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) US6 PF17616.2 EIM86146.1 - 0.042 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral unique short region 6 zf-C2H2 PF00096.26 EIM86147.1 - 0.1 13.1 7.1 0.34 11.5 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EIM86147.1 - 0.31 11.1 1.9 0.58 10.2 1.9 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger SDA1 PF05285.12 EIM86147.1 - 0.45 9.9 11.6 0.84 9.0 11.6 1.4 1 0 0 1 1 1 0 SDA1 zf-C2H2_4 PF13894.6 EIM86147.1 - 1.3 10.1 9.4 3.2 8.8 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger NOT2_3_5 PF04153.18 EIM86148.1 - 1.9e-30 105.6 0.1 1.9e-30 105.6 0.1 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family HMG_box PF00505.19 EIM86149.1 - 6.9e-09 36.0 1.5 2.3e-08 34.3 1.5 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM86149.1 - 0.003 18.1 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF4763 PF15960.5 EIM86149.1 - 0.026 13.9 0.8 0.054 12.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Occludin_ELL PF07303.13 EIM86149.1 - 0.13 13.0 0.1 0.29 11.9 0.1 1.5 1 0 0 1 1 1 0 Occludin homology domain ZapB PF06005.12 EIM86149.1 - 0.4 11.2 2.7 0.73 10.3 2.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Macoilin PF09726.9 EIM86149.1 - 0.46 9.0 3.1 0.91 8.0 3.1 1.4 1 0 0 1 1 1 0 Macoilin family HMG_box PF00505.19 EIM86150.1 - 6.3e-12 45.7 7.5 3.2e-11 43.5 7.5 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM86150.1 - 3.8e-06 27.4 2.1 5.4e-06 26.9 2.1 1.3 1 0 0 1 1 1 1 HMG-box domain zf-C2H2 PF00096.26 EIM86152.1 - 0.013 15.9 28.0 0.048 14.1 0.6 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM86152.1 - 0.33 11.9 31.9 1.3 10.1 1.9 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger SSF PF00474.17 EIM86153.1 - 2.1e-14 53.3 30.1 2.1e-14 53.3 30.1 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Amidase PF01425.21 EIM86154.1 - 7.6e-100 335.0 0.0 1.1e-99 334.4 0.0 1.2 1 0 0 1 1 1 1 Amidase HMG_box PF00505.19 EIM86156.1 - 1.2e-06 28.9 0.0 3.4e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box zf-MYND PF01753.18 EIM86158.1 - 3.1e-05 24.0 14.5 3.1e-05 24.0 14.5 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EIM86158.1 - 6 7.2 9.4 8.4 6.8 8.2 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding ENTH PF01417.20 EIM86159.1 - 4.5e-45 152.7 0.2 6.8e-45 152.2 0.2 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EIM86159.1 - 0.016 14.2 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 ANTH domain SHD1 PF03983.12 EIM86160.1 - 0.029 14.2 0.1 0.069 13.0 0.1 1.7 1 1 0 1 1 1 0 SLA1 homology domain 1, SHD1 SHD1 PF03983.12 EIM86161.1 - 0.029 14.2 0.1 0.069 13.0 0.1 1.7 1 1 0 1 1 1 0 SLA1 homology domain 1, SHD1 Pkinase PF00069.25 EIM86162.1 - 5.5e-07 29.2 0.0 2.3e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Glyco_hydro_20 PF00728.22 EIM86163.1 - 2.9e-87 293.3 0.0 3.6e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EIM86163.1 - 1.7e-16 61.1 0.0 3.2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EIM86163.1 - 3.4e-08 34.3 0.1 8.5e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Peptidase_M36 PF02128.15 EIM86164.1 - 2.4e-135 451.4 4.6 4.2e-135 450.7 4.6 1.4 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EIM86164.1 - 0.00048 19.9 0.1 0.0014 18.4 0.1 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif GSIII_N PF12437.8 EIM86164.1 - 0.0027 17.4 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal ATP-synt_C PF00137.21 EIM86165.1 - 2.7e-31 107.7 35.9 8.9e-22 77.2 15.4 3.3 2 1 1 3 3 3 3 ATP synthase subunit C DUF2970 PF11174.8 EIM86165.1 - 0.03 14.2 6.9 0.049 13.5 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) CCDC106 PF15794.5 EIM86166.1 - 0.062 13.0 0.2 0.099 12.3 0.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Aldedh PF00171.22 EIM86167.1 - 2.1e-118 395.8 0.0 2.4e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family dsrm PF00035.26 EIM86169.1 - 0.0001 22.9 0.1 0.00015 22.4 0.1 1.4 1 1 0 1 1 1 1 Double-stranded RNA binding motif Nanovirus_coat PF04660.12 EIM86169.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Nanovirus coat protein Aldedh PF00171.22 EIM86170.1 - 2.2e-117 392.4 0.0 2.6e-117 392.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ALG11_N PF15924.5 EIM86171.1 - 3.4e-89 298.4 0.1 5.3e-89 297.8 0.1 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EIM86171.1 - 1.5e-23 83.2 0.0 2.5e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIM86171.1 - 3.9e-11 43.5 0.1 7.7e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EIM86171.1 - 0.003 17.6 0.1 0.0078 16.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 RRF_GI PF12614.8 EIM86171.1 - 0.097 12.8 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Ribosome recycling factor TPMT PF05724.11 EIM86174.1 - 2.9e-34 118.6 0.0 3.3e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EIM86174.1 - 1.3e-11 45.1 0.0 1.6e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM86174.1 - 2.6e-09 37.6 0.0 3.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM86174.1 - 5.8e-09 35.9 0.0 8.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86174.1 - 1.5e-07 32.0 0.0 2.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM86174.1 - 2.2e-05 24.4 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Sensor_TM1 PF13755.6 EIM86175.1 - 0.24 11.2 0.7 0.43 10.3 0.7 1.3 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain DUF1854 PF08909.11 EIM86176.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) WD40 PF00400.32 EIM86177.1 - 0.00085 20.1 0.3 4.4 8.3 0.0 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM86177.1 - 0.00087 19.5 0.0 0.81 10.0 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Sporozoite_P67 PF05642.11 EIM86177.1 - 7.5 4.5 12.2 15 3.5 12.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glucosamine_iso PF01182.20 EIM86178.1 - 2.4e-19 70.1 0.0 3.7e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FMN_dh PF01070.18 EIM86179.1 - 7.3e-109 364.0 0.1 1e-108 363.5 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EIM86179.1 - 1.2e-07 31.4 0.1 0.028 13.7 0.0 3.1 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EIM86179.1 - 1.2e-05 24.5 0.2 0.0002 20.5 0.1 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EIM86179.1 - 2.7e-05 23.5 0.1 4.1e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EIM86179.1 - 0.00011 21.7 0.1 0.00018 21.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase TPR_10 PF13374.6 EIM86180.1 - 5.7e-172 553.8 3.0 4.1e-13 48.7 0.0 13.4 14 0 0 14 14 14 13 Tetratricopeptide repeat TPR_12 PF13424.6 EIM86180.1 - 3.1e-154 501.6 23.4 2e-16 60.0 0.0 12.2 1 1 12 13 13 13 13 Tetratricopeptide repeat TPR_7 PF13176.6 EIM86180.1 - 9.2e-57 185.0 4.0 0.00068 19.5 0.0 13.2 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_19 PF14559.6 EIM86180.1 - 9.4e-41 138.2 0.0 0.15 12.6 0.0 13.0 3 3 10 13 13 13 10 Tetratricopeptide repeat TPR_2 PF07719.17 EIM86180.1 - 1.4e-34 115.4 2.5 1 9.7 0.0 13.0 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86180.1 - 2.6e-32 109.3 8.3 0.66 9.9 0.0 13.1 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_17 PF13431.6 EIM86180.1 - 4.1e-31 105.1 8.4 0.87 10.1 0.0 13.1 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86180.1 - 1e-29 102.9 0.0 0.59 10.8 0.0 12.9 8 2 5 13 13 13 6 Tetratricopeptide repeat TPR_4 PF07721.14 EIM86180.1 - 1.5e-21 74.7 0.0 1.8 9.5 0.0 12.7 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM86180.1 - 1.4e-20 71.7 11.3 11 6.6 0.0 13.1 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM86180.1 - 4.1e-20 72.4 20.1 5.5e-07 29.3 1.0 4.9 1 1 4 6 6 6 6 MalT-like TPR region DUF4074 PF13293.6 EIM86180.1 - 1.5e-12 47.6 8.4 39 4.7 0.0 12.0 13 0 0 13 13 13 0 Domain of unknown function (DUF4074) TPR_14 PF13428.6 EIM86180.1 - 7.6e-11 41.9 14.4 89 4.3 0.0 12.4 13 0 0 13 13 13 0 Tetratricopeptide repeat PPR PF01535.20 EIM86180.1 - 5.5e-10 38.8 1.5 67 4.1 0.0 11.4 13 0 0 13 13 13 0 PPR repeat zf-Mss51 PF13824.6 EIM86180.1 - 1.3e-07 31.6 0.0 11 6.2 0.0 6.1 5 0 0 5 5 5 0 Zinc-finger of mitochondrial splicing suppressor 51 partial_CstF PF15861.5 EIM86180.1 - 8.4e-05 22.3 12.4 9.8 6.1 0.0 6.8 5 1 1 6 6 6 0 Partial cleavage stimulation factor domain Metallophos_3 PF14582.6 EIM86180.1 - 0.00021 20.7 0.2 14 4.9 0.0 5.8 3 2 3 7 7 7 0 Metallophosphoesterase, calcineurin superfamily Urocanase_N PF17391.2 EIM86180.1 - 0.0022 17.7 11.9 73 3.1 0.1 8.9 8 3 3 12 12 12 0 Urocanase N-terminal domain TPP_enzyme_M PF00205.22 EIM86180.1 - 0.0071 16.1 5.4 1.1e+02 2.5 0.0 7.2 5 2 5 10 10 10 0 Thiamine pyrophosphate enzyme, central domain TPR_11 PF13414.6 EIM86180.1 - 0.038 13.7 15.1 2.4e+02 1.5 0.0 9.4 11 0 0 11 11 10 0 TPR repeat DUF4023 PF13215.6 EIM86180.1 - 0.043 13.8 0.0 47 4.1 0.0 4.3 3 0 0 3 3 2 0 Protein of unknown function (DUF4023) DUF4749 PF15936.5 EIM86180.1 - 3.4 8.8 5.1 2.3e+02 3.0 0.1 5.0 3 2 2 5 5 4 0 Domain of unknown function (DUF4749) DUF2001 PF09393.10 EIM86180.1 - 3.4 7.6 11.4 1.4e+02 2.4 0.1 6.6 7 1 1 8 8 7 0 Phage tail tube protein FMN_dh PF01070.18 EIM86182.1 - 0.057 12.4 0.0 0.14 11.2 0.0 1.5 1 1 0 1 1 1 0 FMN-dependent dehydrogenase FMN_dh PF01070.18 EIM86183.1 - 1.2e-90 304.1 0.1 1.5e-90 303.7 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EIM86183.1 - 1.5e-07 31.0 0.2 0.042 13.2 0.0 3.4 4 0 0 4 4 4 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EIM86183.1 - 5.1e-05 22.4 0.8 0.00028 20.0 0.1 2.2 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EIM86183.1 - 7e-05 22.4 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EIM86183.1 - 0.00027 20.2 0.1 0.00042 19.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase TPR_10 PF13374.6 EIM86184.1 - 1.2e-159 514.6 7.6 3.6e-11 42.5 0.0 15.0 14 1 0 14 14 14 14 Tetratricopeptide repeat TPR_12 PF13424.6 EIM86184.1 - 1.4e-123 403.3 25.6 1.3e-16 60.6 0.1 12.1 4 3 9 13 13 13 13 Tetratricopeptide repeat TPR_7 PF13176.6 EIM86184.1 - 7.6e-59 191.5 8.0 0.0035 17.3 0.0 14.3 14 0 0 14 14 14 13 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86184.1 - 2.2e-34 115.8 6.0 0.25 11.2 0.0 14.1 14 0 0 14 14 14 10 Tetratricopeptide repeat TPR_2 PF07719.17 EIM86184.1 - 2.9e-32 108.2 10.4 0.95 9.7 0.0 14.1 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 EIM86184.1 - 6.5e-30 103.4 0.0 0.4 11.2 0.0 13.4 11 2 3 14 14 14 5 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86184.1 - 2.8e-29 101.5 0.0 1.3 9.7 0.0 13.4 13 1 1 14 14 14 5 Tetratricopeptide repeat TPR_4 PF07721.14 EIM86184.1 - 4.1e-28 95.1 0.0 0.071 13.8 0.1 13.6 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_17 PF13431.6 EIM86184.1 - 2.7e-25 86.9 8.1 1.5 9.4 0.0 13.5 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM86184.1 - 9e-19 68.0 17.9 1.6e-06 27.7 3.5 5.0 1 1 3 5 5 5 5 MalT-like TPR region TPR_8 PF13181.6 EIM86184.1 - 1.2e-11 43.9 17.2 6.2 7.3 0.0 12.4 14 0 0 14 14 13 1 Tetratricopeptide repeat PPR PF01535.20 EIM86184.1 - 1.3e-11 43.9 4.3 11 6.5 0.0 11.5 14 0 0 14 14 13 0 PPR repeat TPR_14 PF13428.6 EIM86184.1 - 4e-11 42.8 12.5 26 6.0 0.0 12.3 14 0 0 14 14 12 0 Tetratricopeptide repeat DUF4074 PF13293.6 EIM86184.1 - 5.3e-06 26.6 6.2 59 4.1 0.0 10.0 13 0 0 13 13 12 0 Domain of unknown function (DUF4074) Urocanase_N PF17391.2 EIM86184.1 - 7.3e-06 25.7 8.0 1.6 8.4 0.1 9.1 9 3 3 12 12 12 1 Urocanase N-terminal domain TPP_enzyme_M PF00205.22 EIM86184.1 - 0.00039 20.2 3.6 71 3.1 0.1 7.7 4 4 4 8 8 8 0 Thiamine pyrophosphate enzyme, central domain DUF1924 PF09086.11 EIM86184.1 - 0.0014 19.0 0.2 9.5 6.7 0.0 4.6 4 2 1 5 5 5 0 Domain of unknown function (DUF1924) CutA1 PF03091.15 EIM86184.1 - 0.0062 16.4 31.4 6.9 6.6 0.1 10.7 2 2 10 14 14 14 1 CutA1 divalent ion tolerance protein TPR_11 PF13414.6 EIM86184.1 - 0.0093 15.6 8.5 1.1e+02 2.5 0.1 8.9 13 0 0 13 13 13 0 TPR repeat DUF4919 PF16266.5 EIM86184.1 - 0.02 14.8 0.1 11 5.9 0.0 4.7 5 1 1 6 6 6 0 Domain of unknown function (DUF4919) RPN6_N PF18055.1 EIM86184.1 - 0.16 12.3 5.1 2.9 8.3 0.0 4.8 4 3 2 7 7 7 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_6 PF13174.6 EIM86184.1 - 0.61 10.8 28.1 14 6.6 0.0 11.6 14 0 0 14 14 14 0 Tetratricopeptide repeat Phage_CP76 PF06892.11 EIM86184.1 - 1.2 8.7 3.4 42 3.6 0.0 4.0 3 1 1 4 4 4 0 Phage regulatory protein CII (CP76) AAA PF00004.29 EIM86185.1 - 2.4e-38 131.6 0.0 3.5e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM86185.1 - 2.6e-07 30.3 0.0 6.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EIM86185.1 - 2.8e-07 30.4 0.0 6.6e-07 29.2 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EIM86185.1 - 1.9e-06 28.4 0.1 0.00032 21.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EIM86185.1 - 4.5e-05 23.5 0.0 9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EIM86185.1 - 7.3e-05 22.8 0.3 0.00056 19.9 0.3 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM86185.1 - 7.9e-05 23.0 0.1 0.0047 17.2 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EIM86185.1 - 0.0001 22.5 0.0 0.00025 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EIM86185.1 - 0.00025 20.5 0.1 0.0016 17.9 0.2 1.9 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EIM86185.1 - 0.00036 20.5 0.1 0.00092 19.2 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 EIM86185.1 - 0.00036 20.8 0.0 0.0024 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIM86185.1 - 0.00042 20.9 0.0 0.00076 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIM86185.1 - 0.00051 20.2 0.0 0.00084 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EIM86185.1 - 0.00076 18.9 0.0 1.4 8.3 0.0 2.9 2 1 1 3 3 3 2 Bacterial TniB protein RNA_helicase PF00910.22 EIM86185.1 - 0.0012 19.1 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EIM86185.1 - 0.0021 17.6 0.1 0.011 15.3 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EIM86185.1 - 0.0022 17.8 0.1 0.0041 16.9 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EIM86185.1 - 0.0035 16.6 0.1 0.0064 15.7 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 EIM86185.1 - 0.0052 16.7 0.1 0.016 15.1 0.1 1.9 2 0 0 2 2 1 1 NACHT domain AAA_25 PF13481.6 EIM86185.1 - 0.0054 16.3 0.3 0.084 12.4 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 EIM86185.1 - 0.007 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EIM86185.1 - 0.0079 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.6 EIM86185.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIM86185.1 - 0.011 15.1 0.1 0.022 14.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EIM86185.1 - 0.012 15.3 0.0 0.044 13.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EIM86185.1 - 0.013 15.4 0.0 0.17 11.7 0.0 2.1 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EIM86185.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EIM86185.1 - 0.016 15.8 0.1 0.077 13.5 0.1 2.0 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 EIM86185.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EIM86185.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 EIM86185.1 - 0.042 13.0 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Hydin_ADK PF17213.3 EIM86185.1 - 0.042 14.1 0.1 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_3 PF07726.11 EIM86185.1 - 0.097 12.5 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EIM86185.1 - 0.12 11.7 0.0 0.62 9.4 0.0 1.9 1 1 1 2 2 2 0 KaiC SMC_N PF02463.19 EIM86185.1 - 0.15 11.4 0.0 7 6.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SKI PF01202.22 EIM86185.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase KAP_NTPase PF07693.14 EIM86185.1 - 0.19 10.9 0.2 9.8 5.3 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Peptidase_S24 PF00717.23 EIM86186.1 - 2.8e-11 43.2 0.0 5.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EIM86186.1 - 1.4e-05 24.9 0.0 0.055 13.3 0.0 3.0 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Pyr_redox_2 PF07992.14 EIM86187.1 - 2.8e-47 161.4 0.0 3.3e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM86187.1 - 2.7e-16 59.9 0.1 2.2e-14 53.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM86187.1 - 3e-16 59.6 0.3 6.1e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM86187.1 - 0.00022 20.4 2.6 0.13 11.3 0.2 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM86187.1 - 0.00043 20.4 0.5 0.029 14.6 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM86187.1 - 0.0012 18.2 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EIM86187.1 - 0.0055 15.8 1.0 0.12 11.4 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EIM86187.1 - 0.0061 16.2 0.7 0.61 9.6 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EIM86187.1 - 0.023 13.9 0.0 0.92 8.6 0.0 2.5 1 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EIM86187.1 - 0.031 14.7 0.0 0.27 11.7 0.0 2.4 2 2 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 EIM86187.1 - 0.034 13.5 0.1 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIM86187.1 - 0.037 13.3 0.5 0.75 9.0 0.0 2.5 2 1 1 3 3 3 0 FAD binding domain ApbA PF02558.16 EIM86187.1 - 0.098 12.3 1.7 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EIM86187.1 - 0.16 10.7 0.3 1.9 7.1 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Glyco_hydro_20 PF00728.22 EIM86188.1 - 3e-85 286.7 0.0 4.1e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EIM86188.1 - 3.8e-18 66.5 0.0 6.6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EIM86188.1 - 1.6e-09 38.6 0.2 2e-08 35.1 0.1 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Tet_res_leader PF08050.12 EIM86189.1 - 1.4 8.8 3.6 15 5.5 0.4 2.3 2 0 0 2 2 2 0 Tetracycline resistance leader peptide OppC_N PF12911.7 EIM86191.1 - 0.056 13.4 1.0 0.14 12.2 1.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C NapE PF06796.11 EIM86191.1 - 0.7 9.5 3.7 2.3 7.8 0.3 2.4 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF3543 PF12063.8 EIM86193.1 - 0.0088 15.4 0.0 0.0099 15.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) DUF4282 PF14110.6 EIM86196.1 - 0.42 11.4 4.3 0.55 11.0 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) DUF4381 PF14316.6 EIM86197.1 - 0.037 14.3 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TrbC PF04956.13 EIM86197.1 - 0.039 14.2 0.1 0.057 13.7 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family Fungus-induced PF10917.8 EIM86197.1 - 0.073 13.4 0.9 0.13 12.6 0.1 1.8 2 0 0 2 2 2 0 Fungus-induced protein OFeT_1 PF16955.5 EIM86197.1 - 0.08 12.6 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF2615 PF11027.8 EIM86197.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) TRIQK PF15168.6 EIM86197.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Tetraspanin PF00335.20 EIM86198.1 - 0.0013 18.5 14.6 0.0059 16.3 14.6 2.1 1 1 0 1 1 1 1 Tetraspanin family Cir_N PF10197.9 EIM86198.1 - 9.3 6.5 9.9 17 5.7 9.9 1.3 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR COesterase PF00135.28 EIM86199.1 - 6.3e-85 286.0 0.0 4.5e-83 279.9 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM86199.1 - 0.00038 20.4 0.1 0.002 18.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM86199.1 - 0.0034 16.9 0.1 0.007 15.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Trehalase PF01204.18 EIM86201.1 - 4.5e-109 365.6 1.7 1.5e-98 330.9 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 EIM86201.1 - 0.00017 20.6 0.3 0.0024 16.9 0.1 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Vg_Tdu PF07545.14 EIM86202.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Vestigial/Tondu family COesterase PF00135.28 EIM86204.1 - 2.3e-88 297.3 0.0 1.3e-86 291.5 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EIM86204.1 - 0.0023 17.5 0.2 0.0035 16.8 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EIM86204.1 - 0.0027 17.6 0.1 0.007 16.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3419 PF11899.8 EIM86206.1 - 1.6e-140 468.7 0.0 2e-140 468.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 EIM86206.1 - 2.7e-09 37.6 0.0 2.8e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM86206.1 - 7.9e-08 32.3 0.0 3.5e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM86206.1 - 1.1e-07 32.4 0.0 0.00013 22.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86206.1 - 6.1e-07 30.1 0.0 1.4e-05 25.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM86206.1 - 0.00023 20.6 0.0 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EIM86206.1 - 0.00093 19.0 0.0 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EIM86206.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 EIM86206.1 - 0.18 11.3 0.0 0.55 9.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase APH PF01636.23 EIM86207.1 - 7.9e-08 32.5 0.0 1.6e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family GSH_synth_ATP PF03917.17 EIM86208.1 - 1e-128 429.3 0.0 1.2e-128 429.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EIM86208.1 - 4.5e-32 110.6 0.0 7.8e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase GH131_N PF18271.1 EIM86210.1 - 5.7e-82 275.3 0.1 6.4e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain RPAP1_C PF08620.10 EIM86211.1 - 3.2e-20 72.0 0.0 6.3e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EIM86211.1 - 6.6e-06 25.8 1.2 1.3e-05 24.8 1.2 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal CytochromB561_N PF09786.9 EIM86211.1 - 2.9 6.8 12.3 0.29 10.1 6.7 2.1 1 1 0 2 2 2 0 Cytochrome B561, N terminal TPR_10 PF13374.6 EIM86212.1 - 7.8e-104 337.2 0.1 4.7e-13 48.5 0.0 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 EIM86212.1 - 1.3e-70 233.6 0.7 7.9e-13 48.5 0.2 7.9 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 EIM86212.1 - 1.1e-32 109.6 5.1 0.0083 16.1 0.0 8.4 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_4 PF07721.14 EIM86212.1 - 5e-20 70.0 1.2 0.095 13.4 0.6 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86212.1 - 4.6e-18 64.2 0.7 1.6 8.7 0.1 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM86212.1 - 5.1e-18 63.7 4.7 2.6 8.4 0.1 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM86212.1 - 1.9e-16 60.4 5.4 1.6e-07 31.0 0.7 3.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 EIM86212.1 - 1.3e-15 57.7 0.0 4.8 7.8 0.0 8.0 3 3 5 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM86212.1 - 4.5e-14 51.4 7.0 0.98 9.8 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86212.1 - 6.3e-14 52.4 0.0 10 6.9 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 EIM86212.1 - 1.5e-13 50.1 0.4 4.8 7.8 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM86212.1 - 2.5e-09 37.2 10.5 5.2 8.2 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat Urocanase_N PF17391.2 EIM86212.1 - 3.5e-07 29.9 0.1 1.4 8.6 0.0 5.5 5 2 1 6 6 6 2 Urocanase N-terminal domain DUF4074 PF13293.6 EIM86212.1 - 4.2e-07 30.2 0.6 24 5.3 0.0 6.6 8 0 0 8 8 6 0 Domain of unknown function (DUF4074) PPR PF01535.20 EIM86212.1 - 7.9e-06 25.8 0.5 11 6.6 0.0 6.3 7 0 0 7 7 7 0 PPR repeat DUF1897 PF09005.10 EIM86212.1 - 0.00015 21.2 5.0 17 5.0 0.0 6.4 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) Trans_reg_C PF00486.28 EIM86212.1 - 0.00023 21.2 1.2 7.3 6.8 0.0 4.1 3 1 2 5 5 5 0 Transcriptional regulatory protein, C terminal Metallophos_3 PF14582.6 EIM86212.1 - 0.00067 19.1 0.0 0.58 9.4 0.0 4.0 2 1 3 5 5 5 1 Metallophosphoesterase, calcineurin superfamily HSA PF07529.13 EIM86212.1 - 0.078 13.3 0.0 26 5.2 0.0 2.5 2 0 0 2 2 2 0 HSA FlbD PF06289.11 EIM86212.1 - 0.095 12.3 0.5 40 3.9 0.0 3.9 3 0 0 3 3 3 0 Flagellar and Swarming motility proteins DUF5413 PF17434.2 EIM86212.1 - 0.24 11.7 0.8 29 5.0 0.0 3.4 3 1 1 4 4 4 0 Family of unknown function (DUF5413) DUF3157 PF11355.8 EIM86212.1 - 0.34 10.5 10.0 3.5 7.2 0.2 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF3157) cwf21 PF08312.12 EIM86212.1 - 0.34 11.1 10.7 18 5.6 0.0 4.8 4 2 0 4 4 3 0 cwf21 domain TPR_11 PF13414.6 EIM86212.1 - 0.92 9.2 13.0 20 4.9 0.1 6.4 9 0 0 9 9 9 0 TPR repeat DUF2001 PF09393.10 EIM86212.1 - 0.93 9.5 6.6 54 3.8 0.1 4.7 3 2 3 6 6 6 0 Phage tail tube protein DUF365 PF04033.12 EIM86212.1 - 1.4 9.3 3.6 28 5.1 0.1 3.6 4 1 1 5 5 4 0 Domain of unknown function (DUF365) DIOX_N PF14226.6 EIM86213.1 - 1.7e-30 106.2 0.0 2.7e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM86213.1 - 1.3e-19 70.5 0.0 2.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 EIM86214.1 - 1.3e-40 139.7 22.1 1.3e-39 136.3 22.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM86214.1 - 1.4e-23 83.4 26.9 1.4e-12 47.2 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EIM86214.1 - 0.0016 16.8 1.6 0.024 13.0 0.0 2.8 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family HIT PF01230.23 EIM86215.1 - 6.3e-25 87.8 0.2 8.4e-25 87.4 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EIM86215.1 - 1.6e-10 41.5 0.1 2.2e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EIM86215.1 - 2.2e-05 24.3 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF5127 PF17168.4 EIM86220.1 - 4.3e-71 239.3 9.8 4.3e-71 239.3 9.8 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM86220.1 - 1.9e-45 154.6 0.3 5.2e-45 153.2 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM86220.1 - 3.8e-35 121.8 1.9 3.8e-35 121.8 1.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) SKG6 PF08693.10 EIM86220.1 - 0.00078 18.8 4.4 0.0016 17.8 4.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4964 PF16334.5 EIM86220.1 - 0.0075 15.8 1.7 0.038 13.5 1.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4964) Phage_Coat_B PF05356.11 EIM86220.1 - 0.066 13.1 1.9 0.21 11.5 1.9 1.9 1 0 0 1 1 1 0 Phage Coat protein B DUF4328 PF14219.6 EIM86220.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Protocadherin PF08374.11 EIM86220.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protocadherin TrbC PF04956.13 EIM86220.1 - 0.15 12.3 1.9 0.24 11.6 0.3 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family RRM_1 PF00076.22 EIM86221.1 - 3e-10 39.8 0.0 6.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EIM86221.1 - 0.00054 20.2 0.4 0.0013 19.0 0.4 1.7 1 0 0 1 1 1 1 PWI domain Methyltransf_25 PF13649.6 EIM86222.1 - 2.1e-14 54.0 0.0 5.4e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM86222.1 - 7.6e-13 48.9 0.0 2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM86222.1 - 4.5e-12 46.0 0.0 9.2e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIM86222.1 - 1.3e-11 44.5 0.1 2e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EIM86222.1 - 1.2e-09 38.2 0.0 8.8e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86222.1 - 8.5e-07 29.6 0.2 6.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EIM86222.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EIM86222.1 - 3.5e-05 23.8 0.0 6.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EIM86222.1 - 7.7e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 EIM86222.1 - 0.00045 21.2 0.0 0.001 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EIM86222.1 - 0.00069 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 EIM86222.1 - 0.0018 18.0 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 EIM86222.1 - 0.002 17.9 0.1 0.0034 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 EIM86222.1 - 0.0046 15.9 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 EIM86222.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Sugarporin_N PF11471.8 EIM86222.1 - 0.027 14.4 1.7 0.054 13.5 1.7 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Methyltransf_10 PF05971.12 EIM86222.1 - 0.046 13.0 0.1 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 RNA methyltransferase Methyltransf_32 PF13679.6 EIM86222.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 EIM86222.1 - 0.18 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Vir_act_alpha_C PF10400.9 EIM86222.1 - 0.19 12.4 0.2 0.37 11.5 0.2 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term BTB PF00651.31 EIM86223.1 - 0.03 14.5 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 BTB/POZ domain SOG2 PF10428.9 EIM86223.1 - 2.9 7.0 13.1 3.6 6.7 13.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EIM86223.1 - 4.6 7.1 14.0 6.9 6.5 14.0 1.3 1 0 0 1 1 1 0 SPX domain zf-C2H2 PF00096.26 EIM86224.1 - 0.0075 16.7 2.2 0.018 15.5 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM86224.1 - 0.021 15.6 2.6 0.081 13.8 2.6 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger SWI-SNF_Ssr4 PF08549.10 EIM86225.1 - 1.4e-26 93.4 5.1 5.2e-18 65.1 0.0 2.3 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1750) Tup_N PF08581.10 EIM86225.1 - 0.08 13.2 0.3 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 Tup N-terminal DUF1840 PF08895.11 EIM86225.1 - 0.09 13.1 0.1 0.09 13.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Siah-Interact_N PF09032.11 EIM86225.1 - 1.2 9.5 6.8 0.17 12.2 2.1 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal Secretin_N_2 PF07655.13 EIM86226.1 - 0.12 13.0 9.1 8.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Proteasome PF00227.26 EIM86227.1 - 5.8e-32 110.7 0.0 6.8e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit RPN1_C PF18051.1 EIM86227.1 - 0.092 12.8 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal FXMRP1_C_core PF12235.8 EIM86228.1 - 0.18 12.5 0.6 0.38 11.4 0.6 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Rot1 PF10681.9 EIM86229.1 - 3.7e-55 186.7 0.9 4.4e-55 186.4 0.9 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Pkinase PF00069.25 EIM86232.1 - 2.9e-36 125.2 0.0 1.8e-23 83.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86232.1 - 3e-25 89.0 0.0 1.6e-19 70.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIM86232.1 - 0.00079 18.8 0.0 0.055 12.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIM86232.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM86232.1 - 0.0053 16.4 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EIM86232.1 - 0.012 14.7 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EIM86232.1 - 0.045 12.5 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Methyltransf_31 PF13847.6 EIM86234.1 - 2.2e-15 56.7 0.0 1.7e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EIM86234.1 - 3.4e-15 56.3 0.0 4.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM86234.1 - 3.8e-13 49.9 0.0 9.5e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM86234.1 - 1.5e-12 48.0 0.0 4.6e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86234.1 - 1.1e-08 35.7 0.0 5.1e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EIM86234.1 - 0.00019 20.8 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EIM86234.1 - 0.00036 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EIM86234.1 - 0.00039 19.8 0.0 0.052 12.9 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 EIM86234.1 - 0.00066 19.2 0.0 0.0087 15.6 0.0 2.0 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Bmt2 PF11968.8 EIM86234.1 - 0.0028 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 NodS PF05401.11 EIM86234.1 - 0.012 15.3 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 EIM86234.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 EIM86234.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EIM86234.1 - 0.042 13.2 0.0 0.086 12.2 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2OG-FeII_Oxy_3 PF13640.6 EIM86235.1 - 0.0016 19.3 0.0 0.053 14.4 0.0 2.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cauli_VI PF01693.16 EIM86236.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Caulimovirus viroplasmin MFS_1 PF07690.16 EIM86237.1 - 5.9e-29 101.1 42.7 8.3e-27 94.0 31.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 EIM86237.1 - 0.069 11.9 5.5 0.048 12.4 3.2 1.9 2 0 0 2 2 2 0 Reduced folate carrier VSP PF03302.13 EIM86238.1 - 0.0053 15.7 3.2 0.0055 15.6 3.2 1.0 1 0 0 1 1 1 1 Giardia variant-specific surface protein COesterase PF00135.28 EIM86239.1 - 3.1e-81 273.8 0.0 2.5e-80 270.8 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM86239.1 - 0.00029 20.8 0.2 0.0022 17.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM86239.1 - 0.021 14.3 0.6 0.05 13.1 0.6 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family polyprenyl_synt PF00348.17 EIM86240.1 - 1.6e-56 191.2 0.0 7.5e-55 185.8 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase Thyroglobulin_1 PF00086.18 EIM86241.1 - 0.17 11.6 5.8 3.8 7.3 0.2 3.3 3 0 0 3 3 3 0 Thyroglobulin type-1 repeat Glycos_transf_3 PF00591.21 EIM86242.1 - 1.8e-76 257.1 0.0 2.3e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EIM86242.1 - 2.6e-09 36.8 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain HisG PF01634.18 EIM86243.1 - 2.3e-51 174.0 0.0 3e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EIM86243.1 - 3.5e-27 94.4 0.0 1e-26 92.9 0.0 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 EIM86243.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like JmjN PF02375.17 EIM86244.1 - 0.011 15.6 0.8 16 5.6 0.0 3.8 3 0 0 3 3 3 0 jmjN domain DUF4892 PF16234.5 EIM86244.1 - 0.67 9.4 4.9 1.6 8.2 0.0 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4892) CE2_N PF17996.1 EIM86246.1 - 0.00022 21.2 0.2 0.061 13.3 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Shisa PF13908.6 EIM86246.1 - 0.16 12.2 0.4 0.31 11.3 0.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1180 PF06679.12 EIM86246.1 - 2.5 8.5 6.1 0.31 11.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) zf-CCHC_4 PF14392.6 EIM86247.1 - 0.11 12.3 4.4 0.11 12.2 3.3 1.6 2 0 0 2 2 2 0 Zinc knuckle PARP PF00644.20 EIM86248.1 - 2.9e-11 43.3 0.0 6.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EIM86248.1 - 6e-07 29.2 0.0 1.8e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme adh_short_C2 PF13561.6 EIM86249.1 - 3e-57 193.9 0.8 3.6e-57 193.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM86249.1 - 2.1e-53 180.7 1.5 2.7e-53 180.4 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM86249.1 - 2.9e-08 33.8 0.7 5e-08 33.1 0.7 1.5 1 0 0 1 1 1 1 KR domain Coprogen_oxidas PF01218.18 EIM86251.1 - 5.3e-129 429.2 0.0 6.1e-129 429.0 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase polyprenyl_synt PF00348.17 EIM86252.1 - 8.6e-59 198.7 0.0 1e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase EF1G PF00647.19 EIM86252.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain DEAD PF00270.29 EIM86253.1 - 4.6e-12 46.0 0.0 6.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM86253.1 - 0.0056 16.7 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit OTT_1508_deam PF14441.6 EIM86254.1 - 1.1e-05 25.4 1.9 2.8e-05 24.0 1.9 1.8 1 1 0 1 1 1 1 OTT_1508-like deaminase UQ_con PF00179.26 EIM86256.1 - 1.7e-42 144.4 0.0 2e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EIM86256.1 - 1e-18 66.8 0.5 1.9e-18 66.0 0.5 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 EIM86256.1 - 0.00039 20.3 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain Prok-E2_B PF14461.6 EIM86256.1 - 0.0025 17.5 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Aminotran_1_2 PF00155.21 EIM86257.1 - 7.5e-13 48.4 0.0 2.4e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Egh16-like PF11327.8 EIM86259.1 - 8.9e-36 124.0 4.9 8.9e-36 124.0 4.9 2.8 1 1 0 2 2 2 1 Egh16-like virulence factor SR-25 PF10500.9 EIM86259.1 - 0.03 13.9 1.1 0.03 13.9 1.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Merozoite_SPAM PF07133.11 EIM86259.1 - 0.12 12.4 1.5 0.18 11.8 1.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Pro-kuma_activ PF09286.11 EIM86260.1 - 1.3e-47 161.7 0.4 2.9e-47 160.5 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM86260.1 - 0.00017 21.0 1.5 0.0003 20.1 1.5 1.3 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 EIM86264.1 - 6.1e-38 130.3 0.0 1.4e-37 129.1 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM86264.1 - 0.00057 19.2 2.3 0.00091 18.6 2.3 1.2 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy_3 PF13640.6 EIM86266.1 - 5e-09 36.9 0.0 1.4e-08 35.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_16 PF00722.21 EIM86268.1 - 2.2e-08 33.8 0.0 5.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FAM199X PF15814.5 EIM86268.1 - 7.4 5.5 8.0 17 4.3 8.0 1.6 1 0 0 1 1 1 0 Protein family FAM199X Acetyltransf_10 PF13673.7 EIM86270.1 - 3e-08 33.6 0.0 5.6e-08 32.8 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM86270.1 - 2.7e-06 27.6 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM86270.1 - 7.3e-06 26.3 0.0 9.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM86270.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase 2OG-FeII_Oxy_3 PF13640.6 EIM86271.1 - 6.8e-09 36.5 0.0 1.5e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_7C PF02709.14 EIM86271.1 - 0.033 13.8 0.2 0.11 12.2 0.2 1.8 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase HEXIM PF15313.6 EIM86271.1 - 0.16 12.2 2.2 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Glyco_transf_8 PF01501.20 EIM86272.1 - 4.5e-08 32.9 0.0 2.1e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.16 EIM86273.1 - 1.9e-41 142.2 40.3 6.3e-41 140.5 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM86273.1 - 2.5e-09 36.5 7.0 2.5e-09 36.5 7.0 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EIM86274.1 - 6.6e-30 104.2 54.6 3.7e-25 88.6 35.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.6 EIM86275.1 - 5.1e-11 43.3 0.0 1.4e-10 41.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Clat_adaptor_s PF01217.20 EIM86276.1 - 9.8e-57 190.9 3.1 1.1e-56 190.7 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 EIM86276.1 - 0.0098 15.5 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain ArfGap PF01412.18 EIM86277.1 - 2.2e-34 118.0 2.2 2.4e-34 117.9 0.2 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf 2OG-FeII_Oxy_3 PF13640.6 EIM86278.1 - 4.5e-11 43.5 0.3 2e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EIM86279.1 - 1e-08 35.9 0.0 3.4e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Trep_dent_lipo PF09710.10 EIM86279.1 - 0.049 12.6 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) 2OG-FeII_Oxy_3 PF13640.6 EIM86280.1 - 6.1e-09 36.7 0.0 1.6e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 EIM86281.1 - 2.3e-21 76.4 0.0 4.4e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM86281.1 - 4e-09 36.1 1.6 1.4e-05 24.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM86281.1 - 2.3e-08 34.2 0.5 5.8e-08 32.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM86281.1 - 4.4e-07 29.3 0.1 6.1e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EIM86281.1 - 1.7e-06 27.7 0.2 2.8e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EIM86281.1 - 2e-06 27.6 2.5 4.5e-06 26.5 2.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EIM86281.1 - 0.00053 19.4 2.0 0.032 13.5 0.2 2.6 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EIM86281.1 - 0.00078 20.0 0.3 0.0075 16.8 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM86281.1 - 0.00085 18.5 3.5 0.00085 18.5 3.5 1.9 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.22 EIM86281.1 - 0.0018 17.4 1.2 0.0032 16.6 1.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EIM86281.1 - 0.0025 17.1 0.2 0.0048 16.2 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EIM86281.1 - 0.0028 16.4 1.6 0.0057 15.4 1.6 1.7 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM86281.1 - 0.019 14.2 0.4 0.074 12.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM86281.1 - 0.049 12.5 5.0 3 6.6 0.1 2.4 2 1 1 3 3 3 0 Tryptophan halogenase MCRA PF06100.11 EIM86281.1 - 0.062 12.1 0.1 0.091 11.5 0.1 1.2 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 EIM86281.1 - 0.14 12.1 2.1 4.6 7.2 0.5 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 EIM86281.1 - 0.35 10.5 1.8 1.2 8.8 1.5 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA SIR2 PF02146.17 EIM86282.1 - 4.9e-52 176.4 0.0 6.2e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zf-MYND PF01753.18 EIM86283.1 - 1.1e-09 38.3 16.1 2e-09 37.4 16.1 1.5 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 EIM86283.1 - 1.2 6.9 5.3 1.8 6.3 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 EB1 PF03271.17 EIM86285.1 - 6.1e-16 58.4 1.6 6.1e-16 58.4 1.6 1.7 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 EIM86285.1 - 1.1e-06 28.7 0.1 2.1e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain tRNA-synt_1c PF00749.21 EIM86286.1 - 8.2e-103 343.6 0.0 3.3e-102 341.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EIM86286.1 - 8e-31 107.2 0.0 1.5e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Chitin_synth_1 PF01644.17 EIM86291.1 - 2.5e-80 268.2 0.1 3.7e-80 267.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIM86291.1 - 6.5e-29 99.7 0.1 1.6e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIM86291.1 - 1e-22 80.5 0.1 1.9e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIM86291.1 - 0.0046 16.9 9.6 0.034 14.1 9.6 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF1218 PF06749.12 EIM86291.1 - 0.17 12.5 3.9 7.6 7.1 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) APH PF01636.23 EIM86292.1 - 1.8e-07 31.4 0.9 1.1e-06 28.7 0.9 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family SWI-SNF_Ssr4 PF08549.10 EIM86294.1 - 4 6.0 13.8 5.6 5.5 13.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MCPVI PF02993.14 EIM86295.1 - 0.082 12.7 0.1 0.093 12.6 0.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Pkinase PF00069.25 EIM86297.1 - 8.8e-14 51.5 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86297.1 - 0.00082 18.7 0.0 0.0019 17.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Gram_pos_anchor PF00746.21 EIM86298.1 - 0.011 15.6 1.2 0.011 15.6 1.2 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Polysacc_synt_C PF14667.6 EIM86298.1 - 0.05 13.7 0.5 0.097 12.7 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PTP_tm PF18861.1 EIM86298.1 - 0.092 12.7 1.1 0.16 11.9 0.6 1.5 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Syndecan PF01034.20 EIM86298.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 EIM86298.1 - 0.36 10.3 1.2 0.89 9.0 1.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Methyltransf_2 PF00891.18 EIM86299.1 - 8.8e-21 74.2 0.0 9.6e-20 70.8 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EIM86299.1 - 0.0019 18.8 0.0 0.0086 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86299.1 - 0.0024 18.6 0.0 0.0064 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM86299.1 - 0.0052 16.6 0.0 0.025 14.4 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_2 PF00891.18 EIM86300.1 - 6.7e-33 113.8 0.0 1.9e-31 109.0 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EIM86300.1 - 0.0011 19.6 0.0 0.005 17.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DprA_WH PF17782.1 EIM86300.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 DprA winged helix domain RPA_C PF08784.11 EIM86300.1 - 0.0074 16.9 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal HTH_36 PF13730.6 EIM86300.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain EthD PF07110.11 EIM86301.1 - 2.9e-16 60.4 0.0 3.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EIM86301.1 - 1.7e-10 41.4 0.0 2.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase NAD_binding_10 PF13460.6 EIM86302.1 - 3.7e-10 40.0 0.0 4.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM86302.1 - 7.4e-10 38.7 0.0 6.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM86302.1 - 0.00044 19.7 0.0 0.0018 17.8 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EIM86302.1 - 0.0059 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EIM86302.1 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family ADH_zinc_N PF00107.26 EIM86302.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 EIM86302.1 - 0.019 14.1 0.0 0.097 11.7 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain UDPG_MGDP_dh_N PF03721.14 EIM86302.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fibrillarin PF01269.17 EIM86302.1 - 0.048 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin NAD_binding_10 PF13460.6 EIM86304.1 - 4.2e-23 82.2 0.0 5.8e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM86304.1 - 0.001 18.3 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GMC_oxred_N PF00732.19 EIM86305.1 - 4.7e-45 154.2 0.0 5.4e-26 91.7 0.1 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM86305.1 - 4.6e-25 88.8 0.0 9e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM86305.1 - 2.2e-05 24.6 0.6 0.00036 20.7 0.5 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM86305.1 - 3.6e-05 23.0 0.2 5.6e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIM86305.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM86305.1 - 0.00016 20.9 0.4 0.00024 20.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM86305.1 - 0.00016 21.4 0.2 0.00033 20.3 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM86305.1 - 0.00093 18.0 0.1 0.0015 17.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM86305.1 - 0.01 15.1 0.2 0.032 13.5 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM86305.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 EIM86305.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Epimerase PF01370.21 EIM86306.1 - 3e-12 46.5 0.0 8.3e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM86306.1 - 1.3e-11 44.7 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM86306.1 - 1.9e-07 30.9 0.0 1e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 EIM86306.1 - 0.0004 20.6 0.0 0.00062 20.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 EIM86306.1 - 0.0014 18.1 0.0 0.025 14.0 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM86306.1 - 0.002 17.2 0.0 0.0047 16.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fibrillarin PF01269.17 EIM86306.1 - 0.005 16.0 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin ADH_zinc_N PF00107.26 EIM86306.1 - 0.018 15.0 0.1 0.044 13.8 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 EIM86306.1 - 0.039 13.1 0.0 0.33 10.0 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain Rossmann-like PF10727.9 EIM86306.1 - 0.04 13.8 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain DapB_N PF01113.20 EIM86306.1 - 0.043 13.9 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EIM86306.1 - 0.058 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LDcluster4 PF18306.1 EIM86306.1 - 0.061 12.9 0.3 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 SLOG cluster4 family NAD_binding_4 PF07993.12 EIM86306.1 - 0.11 11.6 0.1 4.2 6.4 0.1 2.8 1 1 0 1 1 1 0 Male sterility protein Pyr_redox_2 PF07992.14 EIM86307.1 - 2.8e-15 56.3 0.0 5.2e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIM86307.1 - 4.9e-15 54.9 0.0 1.8e-13 49.8 0.0 2.4 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM86307.1 - 1.7e-11 44.0 0.1 1.5e-05 24.4 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM86307.1 - 2.3e-10 40.6 0.4 0.00065 19.4 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EIM86307.1 - 9.1e-10 38.2 0.0 1.2e-08 34.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EIM86307.1 - 6.3e-09 35.9 0.4 1.7e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EIM86307.1 - 7.7e-06 26.0 0.1 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EIM86307.1 - 3.3e-05 23.9 1.8 0.43 10.5 0.0 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EIM86307.1 - 4.6e-05 23.9 2.4 0.0015 19.1 0.7 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EIM86307.1 - 8.8e-05 22.9 0.0 0.016 15.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EIM86307.1 - 0.0013 17.9 5.4 0.24 10.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EIM86307.1 - 0.0027 17.0 0.9 0.82 8.9 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.24 EIM86307.1 - 0.0037 16.6 0.0 1.2 8.3 0.0 3.2 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.22 EIM86307.1 - 0.0044 16.2 3.4 0.18 10.9 0.8 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EIM86307.1 - 0.0056 16.0 2.0 0.17 11.1 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIM86307.1 - 0.015 14.0 6.0 0.73 8.5 0.1 3.4 4 0 0 4 4 4 0 HI0933-like protein FAD_oxidored PF12831.7 EIM86307.1 - 0.041 13.2 2.4 0.58 9.4 2.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EIM86307.1 - 0.063 12.6 3.0 0.45 9.8 1.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EIM86307.1 - 0.078 11.8 2.5 1.6 7.5 0.4 2.4 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 EIM86307.1 - 0.094 12.4 2.2 0.71 9.5 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EIM86307.1 - 0.1 12.0 1.3 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.17 EIM86307.1 - 0.12 12.9 1.7 2.2 8.9 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF4147 PF13660.6 EIM86307.1 - 0.14 11.7 0.1 7.6 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Sacchrp_dh_NADP PF03435.18 EIM86307.1 - 0.25 11.6 1.2 4.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_transf_8 PF01501.20 EIM86308.1 - 1.1e-14 54.6 1.7 2.6e-14 53.4 1.7 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 EIM86308.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase NAD_binding_10 PF13460.6 EIM86309.1 - 1.1e-09 38.4 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM86309.1 - 1.1e-08 34.8 0.0 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EIM86309.1 - 2.6e-06 27.2 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM86309.1 - 0.0099 15.3 0.1 0.11 11.9 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Fibrillarin PF01269.17 EIM86309.1 - 0.017 14.2 0.0 0.053 12.6 0.0 1.7 2 0 0 2 2 2 0 Fibrillarin Semialdhyde_dh PF01118.24 EIM86309.1 - 0.024 15.1 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EIM86309.1 - 0.036 14.3 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.26 EIM86309.1 - 0.051 13.6 0.0 0.28 11.1 0.0 2.2 2 2 1 3 3 3 0 Zinc-binding dehydrogenase DapB_N PF01113.20 EIM86309.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EIM86309.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EIM86309.1 - 0.21 10.6 0.0 0.38 9.8 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain GMC_oxred_C PF05199.13 EIM86310.1 - 3.5e-19 69.8 0.0 4.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GST_N PF02798.20 EIM86312.1 - 7.3e-17 61.5 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM86312.1 - 4.4e-14 52.6 0.0 8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM86312.1 - 4.9e-14 52.3 0.0 7.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM86312.1 - 2.4e-10 40.6 0.0 3.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM86312.1 - 9.3e-06 25.6 0.1 1.7e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM86312.1 - 1.7e-05 24.9 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.13 EIM86313.1 - 3.8e-25 88.8 0.1 4.9e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM86313.1 - 2.1e-12 47.3 0.1 6e-12 45.8 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM86313.1 - 1.4e-05 24.7 0.1 0.00014 21.4 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM86313.1 - 0.00014 21.9 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EIM86313.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM86313.1 - 0.0078 15.6 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EIM86313.1 - 0.02 15.5 0.6 0.049 14.2 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Phage_Coat_A PF05357.13 EIM86315.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage Coat Protein A adh_short PF00106.25 EIM86317.1 - 1.3e-29 103.1 0.0 2.1e-23 82.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM86317.1 - 5.7e-17 62.0 0.0 3.6e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM86317.1 - 6.4e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM86317.1 - 4.2e-05 23.1 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM86317.1 - 0.011 15.1 0.1 0.023 14.1 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EIM86318.1 - 2.9e-16 59.7 0.0 3.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM86318.1 - 6.7e-10 39.2 0.0 1e-09 38.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM86318.1 - 6.4e-06 25.9 0.0 5.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM86318.1 - 5.7e-05 22.7 0.1 0.00017 21.1 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EIM86318.1 - 0.017 14.3 0.0 0.78 8.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 EIM86318.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EIM86318.1 - 0.05 12.6 0.0 0.13 11.2 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.14 EIM86318.1 - 0.059 12.9 0.7 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EIM86318.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 EIM86318.1 - 0.16 11.1 0.1 14 4.7 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein GRP PF07172.11 EIM86322.1 - 0.27 11.9 22.8 9.8e+02 0.5 22.8 2.4 1 1 0 1 1 1 0 Glycine rich protein family p450 PF00067.22 EIM86324.1 - 9.7e-67 225.7 0.0 1.2e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CcmD PF04995.14 EIM86324.1 - 5.4 7.2 5.3 27 5.0 0.1 3.1 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) p450 PF00067.22 EIM86325.1 - 6.6e-66 222.9 0.0 8.2e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PEMT PF04191.13 EIM86326.1 - 5.7e-12 46.0 0.7 2.2e-11 44.1 0.4 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EIM86326.1 - 9.6e-11 42.0 0.2 1.7e-10 41.1 0.1 1.5 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 EIM86326.1 - 0.00083 18.2 0.3 0.0011 17.9 0.3 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIM86326.1 - 0.038 13.5 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.14 EIM86327.1 - 3.4e-11 43.4 0.2 9e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM86327.1 - 5.8e-07 29.9 0.4 5.8e-07 29.9 0.4 2.1 2 1 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM86327.1 - 0.016 14.0 0.1 0.024 13.4 0.1 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF1989 PF09347.10 EIM86327.1 - 0.074 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) O-FucT PF10250.9 EIM86328.1 - 6.7e-09 35.9 0.0 2.1e-07 30.9 0.0 2.7 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase p450 PF00067.22 EIM86329.1 - 9.3e-67 225.8 0.0 1.2e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CotH PF08757.11 EIM86329.1 - 0.019 14.5 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 CotH kinase protein NTP_transf_5 PF14907.6 EIM86329.1 - 0.094 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Aldo_ket_red PF00248.21 EIM86330.1 - 2e-68 230.8 0.0 2.2e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NUFIP2 PF15293.6 EIM86330.1 - 0.084 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 EF-hand_6 PF13405.6 EIM86331.1 - 0.008 16.0 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EIM86331.1 - 0.012 15.1 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 EIM86331.1 - 0.067 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 EF hand Apolipoprotein PF01442.18 EIM86331.1 - 4.1 7.2 13.5 1.2 8.9 1.0 3.2 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain Glyco_hydro_61 PF03443.14 EIM86332.1 - 2.3e-52 177.9 0.1 2.8e-52 177.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 EIM86332.1 - 0.078 13.4 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 MG2 domain Asp PF00026.23 EIM86334.1 - 7.9e-33 114.2 0.1 8.3e-25 87.9 0.3 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM86334.1 - 8.4e-08 32.7 0.6 9.4e-06 26.0 0.2 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal FTCD_C PF04961.12 EIM86335.1 - 0.13 12.0 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase zf-C2H2_12 PF18658.1 EIM86338.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type DIOX_N PF14226.6 EIM86341.1 - 4.4e-29 101.6 0.0 7.5e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM86341.1 - 2.1e-19 69.9 0.0 4.3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 EIM86344.1 - 0.00064 19.6 0.5 0.0037 17.1 0.5 2.4 1 1 0 1 1 1 1 F-box-like Elongin_A PF06881.11 EIM86344.1 - 0.0056 17.2 0.1 0.035 14.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CDC24 PF06395.11 EIM86346.1 - 7.6e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RTA1 PF04479.13 EIM86347.1 - 1e-60 204.9 1.9 1.3e-60 204.6 1.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_61 PF03443.14 EIM86349.1 - 4e-56 190.2 0.3 5.3e-56 189.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EIM86349.1 - 2.2e-10 40.3 12.1 2.2e-10 40.3 12.1 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain O-FucT PF10250.9 EIM86351.1 - 0.007 16.1 0.0 5.6 6.6 0.0 3.0 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase PTPRCAP PF15713.5 EIM86351.1 - 3.9 7.8 10.7 0.42 10.9 3.3 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DNA_ligase_OB_2 PF14743.6 EIM86354.1 - 2.8e-28 97.7 0.5 6.7e-28 96.5 0.5 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 EIM86354.1 - 7.2e-13 48.7 0.0 5e-12 45.9 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EIM86354.1 - 0.00012 22.5 0.2 0.00049 20.5 0.2 1.9 1 1 0 1 1 1 1 RNA ligase Helicase_C PF00271.31 EIM86357.1 - 3.4e-11 43.5 0.0 9.7e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM86357.1 - 3e-10 40.1 0.0 5.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM86357.1 - 0.0028 17.7 0.0 0.0078 16.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 EIM86357.1 - 0.012 14.5 0.1 0.2 10.4 0.0 2.0 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer RecQ_Zn_bind PF16124.5 EIM86357.1 - 0.02 15.6 0.1 0.02 15.6 0.1 2.3 2 0 0 2 2 2 0 RecQ zinc-binding Cir_N PF10197.9 EIM86357.1 - 0.37 11.0 8.1 0.98 9.7 8.1 1.8 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Dsh_C PF12316.8 EIM86358.1 - 0.0071 16.8 2.4 0.01 16.3 2.4 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal HNH_2 PF13391.6 EIM86360.1 - 0.038 14.1 0.1 0.098 12.8 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease GATA PF00320.27 EIM86361.1 - 0.015 14.9 1.3 0.015 14.9 1.3 2.3 3 0 0 3 3 3 0 GATA zinc finger GST_N PF02798.20 EIM86362.1 - 1.9e-19 69.8 0.0 3.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM86362.1 - 2.4e-16 59.9 0.0 3.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM86362.1 - 5.9e-15 55.3 0.0 9.1e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM86362.1 - 4.9e-11 42.8 0.0 8.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM86362.1 - 1e-06 28.6 0.2 3e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM86362.1 - 6.6e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TetR_C_20 PF17925.1 EIM86363.1 - 0.13 12.5 0.1 0.33 11.3 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cytochrom_B561 PF03188.16 EIM86364.1 - 2 8.6 8.5 2.6 8.2 5.2 2.4 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 adh_short_C2 PF13561.6 EIM86366.1 - 6.3e-53 179.7 0.0 9.2e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM86366.1 - 2.6e-43 147.7 0.0 4e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM86366.1 - 1.6e-07 31.5 0.1 3.5e-07 30.3 0.1 1.5 1 1 1 2 2 2 1 KR domain DUF4509 PF14970.6 EIM86366.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) ORC2 PF04084.14 EIM86366.1 - 0.025 13.5 0.0 5.3 5.9 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 2 FANCI_HD1 PF14679.6 EIM86366.1 - 0.17 11.9 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 FANCI helical domain 1 Phosducin PF02114.16 EIM86367.1 - 3.5e-15 55.7 0.0 5.6e-08 32.0 0.1 3.0 2 1 0 2 2 2 2 Phosducin DUF4072 PF13284.6 EIM86367.1 - 1.1 9.8 4.1 8.3 6.9 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) GGACT PF06094.12 EIM86368.1 - 1.3e-06 29.1 0.3 2.8e-05 24.7 0.3 2.1 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EIM86368.1 - 1.6e-05 25.2 0.1 4.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AIG2-like family IFT46_B_C PF12317.8 EIM86369.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF2164 PF09932.9 EIM86370.1 - 0.11 12.5 0.2 0.25 11.4 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) Enamelin PF15362.6 EIM86373.1 - 0.027 12.8 4.0 0.75 8.0 0.2 2.3 1 1 1 2 2 2 0 Enamelin FAD_binding_3 PF01494.19 EIM86375.1 - 1.7e-16 60.4 0.2 2.3e-08 33.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EIM86375.1 - 7.2e-07 28.7 0.7 7e-05 22.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM86375.1 - 2.9e-06 26.7 0.2 5e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EIM86375.1 - 8.3e-06 24.8 0.3 0.00017 20.4 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EIM86375.1 - 2.1e-05 24.3 3.5 0.0014 18.3 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM86375.1 - 2.9e-05 24.2 0.1 0.00019 21.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EIM86375.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM86375.1 - 0.0012 18.2 0.2 0.002 17.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM86375.1 - 0.0026 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EIM86375.1 - 0.0058 17.2 0.3 0.072 13.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM86375.1 - 0.025 13.6 0.9 0.033 13.2 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EIM86375.1 - 0.04 13.1 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EIM86375.1 - 0.076 11.8 0.3 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Vps36-NZF-N PF16988.5 EIM86376.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Thiolase_N PF00108.23 EIM86377.1 - 1e-79 267.6 5.9 2.4e-79 266.4 3.4 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIM86377.1 - 1.9e-45 153.5 0.7 1.9e-45 153.5 0.7 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EIM86377.1 - 0.0025 17.4 5.3 0.0045 16.6 0.7 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EIM86377.1 - 0.079 12.8 1.0 15 5.5 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HTH_7 PF02796.15 EIM86377.1 - 0.079 13.1 0.9 10 6.3 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Oxidored_q2 PF00420.24 EIM86378.1 - 0.00036 20.1 2.9 0.0012 18.5 2.1 1.9 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MraZ PF02381.18 EIM86379.1 - 0.02 14.8 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like DUF575 PF04746.12 EIM86383.1 - 0.031 14.5 0.1 0.052 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Oxidored_q3 PF00499.20 EIM86383.1 - 0.04 13.6 3.1 0.16 11.7 3.1 2.0 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ank_2 PF12796.7 EIM86385.1 - 2.9e-22 79.0 8.4 2.2e-09 37.8 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM86385.1 - 3e-20 72.3 0.8 1.1e-06 29.0 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM86385.1 - 7.7e-14 50.5 0.2 0.24 12.1 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EIM86385.1 - 6.7e-13 48.4 6.0 0.038 14.5 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EIM86385.1 - 2e-07 31.1 1.4 0.034 14.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) FLgD_tudor PF13861.6 EIM86385.1 - 0.0017 18.5 0.1 0.78 10.0 0.1 3.2 1 1 0 1 1 1 1 FlgD Tudor-like domain DUF1843 PF08898.10 EIM86385.1 - 0.0065 16.9 4.1 2.1 8.9 0.2 2.9 2 2 1 3 3 3 2 Domain of unknown function (DUF1843) tRNA_anti_2 PF13742.6 EIM86385.1 - 0.052 13.7 0.0 54 4.1 0.0 3.2 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain VWA_3_C PF18571.1 EIM86385.1 - 0.064 13.1 3.3 38 4.3 0.0 4.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain NdhO PF11910.8 EIM86385.1 - 0.1 12.8 0.1 18 5.6 0.0 3.0 3 0 0 3 3 3 0 Cyanobacterial and plant NDH-1 subunit O YajC PF02699.15 EIM86385.1 - 0.21 11.5 1.0 27 4.7 0.0 3.2 1 1 2 3 3 3 0 Preprotein translocase subunit Goodbye PF17109.5 EIM86386.1 - 3e-19 69.6 0.1 1.5e-18 67.4 0.0 2.3 2 1 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EIM86386.1 - 5.3e-15 55.7 0.0 1.4e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 EIM86386.1 - 0.0018 18.7 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 EIM86386.1 - 0.0027 18.1 0.0 0.017 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EIM86386.1 - 0.05 14.0 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0242 PF06785.11 EIM86389.1 - 0.00034 20.8 10.3 0.0038 17.4 10.4 2.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 EIM86389.1 - 0.0083 16.6 10.7 0.01 16.3 0.4 3.5 3 0 0 3 3 3 1 Fez1 PKcGMP_CC PF16808.5 EIM86389.1 - 0.049 13.5 0.4 0.049 13.5 0.4 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BRCC36_C PF18110.1 EIM86389.1 - 0.38 11.0 2.5 4.2 7.6 0.1 2.9 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain MbeD_MobD PF04899.12 EIM86389.1 - 0.66 10.1 4.8 9.8 6.4 0.1 3.3 3 0 0 3 3 3 0 MbeD/MobD like COG2 PF06148.11 EIM86389.1 - 1.2 9.2 11.7 5.4 7.1 0.4 4.2 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CC2-LZ PF16516.5 EIM86389.1 - 4.5 7.7 9.4 1.6 9.1 0.2 3.8 4 0 0 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4570 PF15134.6 EIM86389.1 - 5 7.2 9.4 1.4 9.0 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4570) FlxA PF14282.6 EIM86389.1 - 6.5 6.8 12.9 10 6.2 0.2 4.6 4 0 0 4 4 4 0 FlxA-like protein Fungal_TACC PF12709.7 EIM86389.1 - 6.7 7.2 7.4 11 6.5 0.1 3.0 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Prefoldin PF02996.17 EIM86389.1 - 8.4 6.3 8.5 87 3.1 0.2 4.6 5 1 1 6 6 6 0 Prefoldin subunit Fungal_trans PF04082.18 EIM86391.1 - 2.1e-20 72.9 0.0 4.7e-20 71.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86391.1 - 0.01 16.0 16.2 0.023 14.8 0.9 3.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Hsk3 PF08227.11 EIM86391.1 - 0.037 14.4 0.8 0.071 13.5 0.8 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like zf-RING-like PF08746.11 EIM86391.1 - 3.7 7.9 6.4 15 6.0 0.0 2.9 3 0 0 3 3 3 0 RING-like domain Hormone_5 PF00184.17 EIM86391.1 - 6.2 7.7 9.9 3 8.7 4.2 2.6 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain Fungal_trans PF04082.18 EIM86392.1 - 3.2e-20 72.3 0.0 5.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86392.1 - 0.00028 21.0 5.3 0.00028 21.0 5.3 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EIM86393.1 - 5.3e-09 35.8 0.5 2.6e-07 30.4 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM86393.1 - 3.4 7.6 5.7 3.1 7.8 1.9 2.8 2 1 0 2 2 2 0 F-box domain He_PIG PF05345.12 EIM86395.1 - 4.7e-11 42.7 23.8 1.1e-07 31.9 6.9 5.0 4 0 0 4 4 4 4 Putative Ig domain MtrG PF04210.13 EIM86395.1 - 0.31 10.9 0.7 0.64 9.9 0.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G HEAT_EZ PF13513.6 EIM86396.1 - 1.7e-18 66.7 10.8 0.0013 19.2 0.0 10.5 10 0 0 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.6 EIM86396.1 - 9.6e-16 58.0 6.2 0.036 14.4 0.0 7.8 7 3 2 10 10 9 6 HEAT repeats HEAT PF02985.22 EIM86396.1 - 1.8e-12 46.4 20.8 0.0058 16.8 0.0 9.3 10 0 0 10 10 9 3 HEAT repeat Cnd1 PF12717.7 EIM86396.1 - 2.2e-08 34.3 0.0 0.0087 16.1 0.0 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EIM86396.1 - 2.2e-07 30.3 0.2 0.0034 16.6 0.0 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) IBN_N PF03810.19 EIM86396.1 - 5.5e-07 29.4 0.7 3.8e-06 26.7 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 EIM86396.1 - 1.8e-05 24.6 0.0 0.021 14.6 0.0 3.9 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EIM86396.1 - 0.00049 20.6 0.0 4.7 7.9 0.0 3.9 4 0 0 4 4 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EIM86396.1 - 0.0016 18.1 0.0 4.2 6.9 0.0 4.8 5 1 1 6 6 6 1 CLASP N terminal DUF3385 PF11865.8 EIM86396.1 - 0.0052 16.7 0.0 12 5.8 0.0 5.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 EIM86396.1 - 0.041 14.1 0.2 29 4.9 0.0 4.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 EIM86396.1 - 0.075 12.1 0.2 12 4.9 0.0 4.1 4 2 1 5 5 5 0 RNAPII transcription regulator C-terminal Dynein_light PF01221.18 EIM86398.1 - 3.2e-37 126.7 0.8 3.5e-37 126.6 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DEAD PF00270.29 EIM86400.1 - 3.1e-15 56.4 0.0 5.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM86400.1 - 3.9e-14 52.9 0.0 1.1e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM86400.1 - 9.6e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 EIM86400.1 - 0.05 14.3 0.1 0.14 12.9 0.1 1.7 1 0 0 1 1 1 0 RecQ zinc-binding UvrD-helicase PF00580.21 EIM86400.1 - 0.22 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Zn_clus PF00172.18 EIM86402.1 - 2.9e-06 27.3 12.7 6.6e-06 26.1 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.13 EIM86403.1 - 2.3e-14 53.1 7.5 3.3e-14 52.6 7.5 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 EIM86403.1 - 0.012 15.0 1.1 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EIM86403.1 - 0.34 10.4 3.3 7 6.3 0.4 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_4 PF13894.6 EIM86403.1 - 0.39 11.7 0.4 0.39 11.7 0.4 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1610 PF07754.11 EIM86403.1 - 2.8 8.0 9.5 8.2 6.5 9.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) F-box-like PF12937.7 EIM86404.1 - 0.067 13.1 0.2 0.067 13.1 0.2 2.3 2 0 0 2 2 2 0 F-box-like Aldo_ket_red PF00248.21 EIM86405.1 - 6.9e-49 166.6 0.0 8e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 3Beta_HSD PF01073.19 EIM86405.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L23 PF00276.20 EIM86406.1 - 1.6e-09 38.0 0.1 3.2e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Glyco_hydro_16 PF00722.21 EIM86408.1 - 4.5e-35 120.7 0.6 6.6e-35 120.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PPV_E2_N PF00508.17 EIM86408.1 - 0.053 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal AIP3 PF03915.13 EIM86409.1 - 3.7e-147 490.7 6.4 5.8e-147 490.0 6.4 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 EIM86409.1 - 0.03 14.1 3.7 0.2 11.4 3.7 2.4 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 EIM86409.1 - 0.054 14.0 0.6 0.054 14.0 0.6 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.9 EIM86409.1 - 0.1 12.5 4.2 0.15 12.0 0.6 2.9 3 1 0 3 3 3 0 Apolipoprotein O ISG65-75 PF11727.8 EIM86409.1 - 0.19 10.9 2.4 0.48 9.6 2.4 1.7 1 0 0 1 1 1 0 Invariant surface glycoprotein Baculo_p24 PF05073.12 EIM86409.1 - 0.91 9.3 4.3 4.1 7.1 4.3 2.2 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF1664 PF07889.12 EIM86409.1 - 1.6 8.8 9.8 0.46 10.5 5.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GRP PF07172.11 EIM86409.1 - 2.4 8.9 22.1 0.78 10.5 12.9 2.7 2 0 0 2 2 2 0 Glycine rich protein family FlaC_arch PF05377.11 EIM86409.1 - 4.2 7.8 7.7 32 5.0 0.3 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 EIM86409.1 - 4.2 8.0 9.7 29 5.3 4.2 3.8 1 1 1 3 3 3 0 Syntaxin 6, N-terminal F-box-like PF12937.7 EIM86410.1 - 5.7e-06 26.1 0.9 8.5e-06 25.6 0.9 1.3 1 0 0 1 1 1 1 F-box-like AviRa PF11599.8 EIM86410.1 - 0.055 12.9 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa zf-MYND PF01753.18 EIM86411.1 - 2.7e-12 46.6 15.6 5.3e-12 45.6 15.0 1.9 1 1 1 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EIM86411.1 - 0.49 10.7 12.9 1.7 9.0 12.9 2.0 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_2 PF07719.17 EIM86412.1 - 0.00073 19.5 1.8 0.012 15.7 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM86412.1 - 0.0015 18.2 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EIM86412.1 - 0.0047 16.7 0.3 0.01 15.6 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86412.1 - 0.0075 16.9 0.1 0.055 14.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2179 PF10035.9 EIM86412.1 - 0.3 10.9 0.6 0.72 9.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF4470 PF14737.6 EIM86413.1 - 3.9e-08 33.4 0.0 1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EIM86413.1 - 9.1e-08 31.7 0.6 0.00019 21.3 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM86413.1 - 4.8e-06 26.1 0.4 1.2e-05 24.9 0.4 1.7 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EIM86413.1 - 4.4e-05 23.1 1.4 0.0019 17.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM86413.1 - 0.006 16.5 0.5 0.056 13.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM86413.1 - 0.0075 16.8 3.3 0.064 13.8 0.4 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86413.1 - 0.0092 16.6 2.4 0.013 16.1 1.1 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM86413.1 - 0.015 16.0 0.0 0.1 13.5 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM86413.1 - 0.02 15.1 0.5 5.3 7.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM86413.1 - 0.043 14.1 0.5 5.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM86413.1 - 0.076 13.3 0.3 0.19 12.0 0.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Takusan PF04822.13 EIM86414.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Takusan DUF4470 PF14737.6 EIM86416.1 - 1.7e-07 31.3 0.0 4.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EIM86416.1 - 0.00044 19.9 0.5 0.0022 17.6 0.4 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EIM86416.1 - 0.00094 19.1 1.6 0.01 15.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86416.1 - 0.016 15.9 1.1 0.045 14.4 1.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86416.1 - 0.15 12.0 0.3 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SLAC1 PF03595.17 EIM86417.1 - 3.1e-55 187.7 46.7 3.5e-55 187.5 46.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 EIM86418.1 - 1.1e-57 195.7 38.3 1.3e-57 195.5 38.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel STE2 PF02116.15 EIM86419.1 - 0.0014 18.0 2.5 0.0014 18.0 2.5 2.8 1 1 0 2 2 2 1 Fungal pheromone mating factor STE2 GPCR STE2 PF02116.15 EIM86420.1 - 0.18 11.1 19.2 6.1 6.1 16.8 2.9 1 1 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DHBP_synthase PF00926.19 EIM86421.1 - 7.2e-86 286.6 0.2 9.3e-86 286.3 0.2 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.27 EIM86422.1 - 9.6e-33 112.0 8.1 5.7e-19 67.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein STE2 PF02116.15 EIM86423.1 - 0.0075 15.6 4.4 0.011 15.0 3.9 1.6 1 1 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2721 PF11026.8 EIM86423.1 - 0.39 10.6 3.7 0.86 9.5 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) zf-MYND PF01753.18 EIM86424.1 - 1.4e-06 28.3 13.5 1.4e-06 28.3 13.5 2.1 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EIM86424.1 - 2.1 8.7 8.2 5.2 7.5 8.2 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding p450 PF00067.22 EIM86425.1 - 2.5e-30 105.6 0.0 3.4e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2911 PF11138.8 EIM86425.1 - 0.04 13.8 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) zf-C2H2 PF00096.26 EIM86426.1 - 3.4e-08 33.5 7.1 0.00048 20.4 0.1 2.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM86426.1 - 1.7e-05 25.0 16.5 0.0013 19.1 0.7 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM86426.1 - 7.3e-05 23.3 12.3 0.024 15.5 0.1 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIM86426.1 - 0.00017 21.5 3.4 0.077 13.0 0.0 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIM86426.1 - 0.0077 16.0 1.3 1 9.2 0.0 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type FOXP-CC PF16159.5 EIM86426.1 - 0.0084 16.7 6.6 0.041 14.5 6.6 1.9 1 1 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EIM86426.1 - 0.12 12.5 1.3 0.47 10.6 0.4 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger Zn-ribbon_8 PF09723.10 EIM86426.1 - 0.84 9.8 5.1 4 7.6 5.0 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 EIM86426.1 - 1.8 8.8 11.2 60 3.9 5.4 2.8 1 1 1 2 2 2 0 AN1-like Zinc finger RRM_1 PF00076.22 EIM86427.1 - 0.095 12.5 0.4 0.76 9.6 0.0 2.7 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYDLN_acid PF09538.10 EIM86427.1 - 0.14 12.8 0.1 0.26 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-ribbon_3 PF13248.6 EIM86427.1 - 0.35 10.4 2.2 0.76 9.3 2.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Atrophin-1 PF03154.15 EIM86428.1 - 0.0013 17.1 15.8 0.0013 17.1 15.8 3.2 2 1 1 3 3 3 1 Atrophin-1 family DUF3824 PF12868.7 EIM86428.1 - 0.0097 16.6 15.0 0.0097 16.6 15.0 4.8 1 1 3 4 4 4 2 Domain of unknwon function (DUF3824) TFIIA PF03153.13 EIM86428.1 - 0.89 9.5 13.6 1.3 8.9 13.6 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SURF2 PF05477.11 EIM86428.1 - 2 8.0 8.8 0.14 11.8 3.6 1.6 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Apt1 PF10351.9 EIM86428.1 - 2.5 6.9 7.1 3.4 6.4 7.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spem1 PF15670.5 EIM86428.1 - 6.7 6.2 14.3 0.86 9.1 8.2 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 Nucleo_P87 PF07267.11 EIM86428.1 - 8.3 5.1 12.0 14 4.4 12.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1768 PF08719.11 EIM86429.1 - 4.8e-22 78.9 0.0 5.6e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) GMC_oxred_N PF00732.19 EIM86430.1 - 2.9e-59 200.9 0.0 4.2e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DHBP_synthase PF00926.19 EIM86430.1 - 4.7e-37 127.4 1.9 1.1e-30 106.5 0.0 2.6 2 1 0 2 2 2 2 3,4-dihydroxy-2-butanone 4-phosphate synthase GMC_oxred_C PF05199.13 EIM86430.1 - 1.8e-35 122.6 0.0 4e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EIM86430.1 - 0.00064 19.0 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM86430.1 - 0.003 16.7 0.9 0.017 14.2 0.2 2.3 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EIM86430.1 - 0.0039 16.8 0.6 0.0088 15.7 0.6 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase RskA PF10099.9 EIM86430.1 - 0.0049 17.2 2.7 0.73 10.1 0.6 2.4 2 0 0 2 2 2 2 Anti-sigma-K factor rskA NAD_binding_8 PF13450.6 EIM86430.1 - 0.015 15.5 1.5 0.038 14.2 0.9 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM86430.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PVL_ORF50 PF07768.11 EIM86430.1 - 0.069 13.5 1.5 0.19 12.1 1.5 1.7 1 0 0 1 1 1 0 PVL ORF-50-like family FAD_binding_3 PF01494.19 EIM86430.1 - 0.1 11.8 0.3 0.49 9.6 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EIM86430.1 - 0.22 12.1 0.8 5.1 7.7 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EIM86431.1 - 3.4e-12 46.3 0.0 5.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86431.1 - 0.00056 19.3 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ThiG PF05690.14 EIM86431.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Vpu PF00558.19 EIM86432.1 - 0.2 11.4 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Vpu protein BTB PF00651.31 EIM86434.1 - 1.8e-06 28.1 0.0 8.5e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain DUF3874 PF12990.7 EIM86434.1 - 0.19 12.1 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) Rhomboid PF01694.22 EIM86435.1 - 1.2e-14 54.6 5.4 1.2e-14 54.6 5.4 2.0 2 1 0 2 2 2 1 Rhomboid family YdjM PF04307.14 EIM86435.1 - 0.027 13.8 1.0 0.054 12.8 1.0 1.6 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase BTB PF00651.31 EIM86436.1 - 3.1e-08 33.8 0.2 4.2e-07 30.2 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain CTNNB1_binding PF08347.11 EIM86436.1 - 0.061 13.5 0.3 0.096 12.9 0.3 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding CHAT PF12770.7 EIM86437.1 - 3.4e-06 26.7 0.1 3.8e-06 26.5 0.1 1.0 1 0 0 1 1 1 1 CHAT domain TAF8_C PF10406.9 EIM86438.1 - 0.0063 17.0 0.0 0.043 14.4 0.1 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term U71 PF17474.2 EIM86438.1 - 0.14 12.1 0.3 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Tegument protein UL11 homolog TPR_10 PF13374.6 EIM86440.1 - 1.9e-11 43.5 37.0 0.00081 19.2 0.0 13.0 16 0 0 16 16 16 3 Tetratricopeptide repeat CHAT PF12770.7 EIM86440.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_14 PF13428.6 EIM86440.1 - 0.00027 21.5 20.4 43 5.3 0.2 10.4 12 0 0 12 12 10 0 Tetratricopeptide repeat SNAP PF14938.6 EIM86440.1 - 0.0042 16.6 1.9 0.2 11.0 0.9 3.2 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 EIM86440.1 - 0.0047 16.4 5.1 0.17 11.2 2.7 3.8 3 2 1 4 4 4 1 MalT-like TPR region TPR_8 PF13181.6 EIM86440.1 - 0.0071 16.5 0.1 11 6.5 0.2 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF3717 PF12512.8 EIM86440.1 - 0.0072 16.2 0.0 2.5 8.1 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3717) TPR_4 PF07721.14 EIM86440.1 - 0.02 15.5 2.4 9.2 7.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM86440.1 - 0.031 14.4 20.7 5 7.5 0.3 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat Complex1_LYR PF05347.15 EIM86440.1 - 0.097 12.7 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Nup88 PF10168.9 EIM86440.1 - 0.11 10.3 0.1 0.16 9.7 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component FRB_dom PF08771.11 EIM86440.1 - 0.13 12.7 0.2 55 4.3 0.0 3.5 2 1 1 3 3 2 0 FKBP12-rapamycin binding domain TPR_16 PF13432.6 EIM86440.1 - 1 10.0 14.3 4.3 8.1 0.0 6.3 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM86440.1 - 1 9.7 28.3 0.35 11.2 0.6 9.9 7 3 6 13 13 13 0 Tetratricopeptide repeat RNase_H PF00075.24 EIM86442.1 - 1.2e-07 32.0 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RNase_H PF00075.24 EIM86443.1 - 1.9e-07 31.3 0.0 5.2e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 EIM86443.1 - 1.5e-05 25.6 0.1 4.6e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Asp PF00026.23 EIM86445.1 - 2e-68 231.1 6.5 2.5e-68 230.8 6.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM86445.1 - 5.4e-09 36.5 5.9 8.3e-07 29.4 0.1 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Histone PF00125.24 EIM86446.1 - 1.9e-49 167.4 4.0 2.1e-49 167.2 4.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EIM86446.1 - 2.7e-05 24.5 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EIM86446.1 - 5.5e-05 23.2 0.1 0.0001 22.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EIM86446.1 - 0.00028 21.5 2.3 0.00035 21.2 2.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EIM86446.1 - 0.00071 19.8 0.1 0.0015 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EIM86446.1 - 0.09 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 EIM86447.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EIM86447.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EIM86447.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EIM86447.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM86447.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EIM86447.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RhoGAP PF00620.27 EIM86448.1 - 5e-46 156.3 0.0 1.2e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EIM86448.1 - 2.2e-13 50.3 0.7 9.1e-12 45.1 0.0 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Golgin_A5 PF09787.9 EIM86448.1 - 0.0023 17.5 2.9 0.0046 16.5 2.9 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF2347 PF09804.9 EIM86448.1 - 0.056 13.0 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Mod_r PF07200.13 EIM86448.1 - 0.057 13.5 8.0 2.6 8.2 2.9 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Adipokin_hormo PF06377.11 EIM86448.1 - 0.059 13.7 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Adipokinetic hormone SOG2 PF10428.9 EIM86448.1 - 0.27 10.4 23.4 0.1 11.8 4.8 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Spc7 PF08317.11 EIM86448.1 - 1.8 7.4 13.1 0.44 9.4 6.6 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF745 PF05335.13 EIM86448.1 - 2.4 7.9 5.7 0.5 10.1 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) F-box-like PF12937.7 EIM86449.1 - 4.8e-08 32.8 2.2 1.1e-05 25.2 0.5 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EIM86449.1 - 0.0009 19.1 4.2 0.0011 18.8 0.6 2.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EIM86449.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 F-box Nucleopor_Nup85 PF07575.13 EIM86450.1 - 6.7e-59 199.9 0.0 9.9e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin BRK PF07533.16 EIM86450.1 - 0.017 14.7 0.0 9.1 6.0 0.0 3.1 3 0 0 3 3 3 0 BRK domain Acetyltransf_10 PF13673.7 EIM86452.1 - 6.4e-06 26.1 0.0 8.5e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM86452.1 - 2.7e-05 24.5 0.0 3.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM86452.1 - 5.8e-05 23.3 0.0 8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EIM86452.1 - 0.043 13.9 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM86452.1 - 0.055 13.4 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein SIR2 PF02146.17 EIM86453.1 - 5e-61 205.7 0.0 9.9e-61 204.7 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EIM86453.1 - 1.3e-07 31.5 0.4 2.5e-05 24.1 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EIM86453.1 - 9.4e-05 22.2 0.5 0.23 11.2 0.0 2.8 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain DUF1272 PF06906.11 EIM86453.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Pkinase_Tyr PF07714.17 EIM86454.1 - 2.8e-31 108.7 0.0 2.2e-30 105.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM86454.1 - 1.1e-26 93.8 0.0 2e-26 93.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EIM86454.1 - 0.00048 19.5 0.0 0.00068 19.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIM86454.1 - 0.0037 16.3 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIM86454.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM86454.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EIM86454.1 - 0.024 14.2 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EIM86454.1 - 0.037 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S9 PF00326.21 EIM86455.1 - 7.3e-33 113.8 0.0 1.1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EIM86455.1 - 4.2e-08 33.0 0.0 9e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EIM86455.1 - 2.6e-06 27.3 0.5 0.00011 22.0 0.6 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EIM86455.1 - 7.8e-06 25.7 0.1 0.02 14.5 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EIM86455.1 - 2.1e-05 24.5 0.0 0.00017 21.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM86455.1 - 0.00035 19.9 0.1 0.063 12.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 EIM86455.1 - 0.00041 19.1 0.2 0.03 13.0 0.2 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.28 EIM86455.1 - 0.0059 15.5 0.0 0.0085 15.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family PAF-AH_p_II PF03403.13 EIM86455.1 - 0.041 12.4 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 EIM86455.1 - 0.046 13.5 0.0 0.16 11.8 0.0 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF2920 PF11144.8 EIM86455.1 - 0.14 11.3 0.3 1.8 7.6 0.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2920) adh_short_C2 PF13561.6 EIM86458.1 - 1.7e-64 217.6 1.7 2.1e-64 217.3 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM86458.1 - 1e-53 181.7 0.9 1.2e-53 181.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM86458.1 - 1.3e-08 35.0 0.2 1.9e-08 34.4 0.2 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 EIM86459.1 - 5.9e-62 209.9 0.0 7.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Smr PF01713.21 EIM86460.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 EIM86460.1 - 2.3e-05 24.7 1.5 3.3e-05 24.2 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) BON PF04972.17 EIM86460.1 - 0.075 13.4 2.7 0.096 13.0 0.6 2.2 3 0 0 3 3 3 0 BON domain CHAT PF12770.7 EIM86461.1 - 2.7e-36 125.5 0.0 5e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 EIM86461.1 - 6.6e-08 32.2 0.4 1.4 9.3 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EIM86461.1 - 2.4e-07 30.4 20.9 0.081 12.8 0.1 10.4 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM86461.1 - 1.6e-06 27.8 2.0 4 7.8 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86461.1 - 7.5e-06 25.5 1.2 11 6.1 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM86461.1 - 0.0063 16.8 21.9 0.22 11.8 0.2 7.5 8 2 2 10 10 10 2 Tetratricopeptide repeat Utp12 PF04003.12 EIM86461.1 - 0.031 14.6 0.5 0.17 12.2 0.2 2.4 2 0 0 2 2 2 0 Dip2/Utp12 Family TPR_7 PF13176.6 EIM86461.1 - 0.93 9.7 9.1 8.4 6.7 0.0 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86461.1 - 1 10.1 11.4 38 5.0 0.1 5.1 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM86461.1 - 1.5 8.6 6.2 23 4.7 0.1 4.8 6 0 0 6 6 6 0 TPR repeat DUF4164 PF13747.6 EIM86461.1 - 5.4 7.4 8.5 4 7.8 0.1 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4164) RNase_H PF00075.24 EIM86462.1 - 3.8e-07 30.4 0.0 1.1e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 EIM86462.1 - 2.7e-05 24.8 0.1 8.2e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase GPI-anchored PF10342.9 EIM86464.1 - 2.3e-06 28.3 1.2 7e-06 26.7 1.3 1.8 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PA_decarbox PF05870.11 EIM86466.1 - 1.5e-08 34.4 0.1 1.6e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) DUF2015 PF09435.10 EIM86468.1 - 1.8e-32 111.5 0.0 2.2e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF98 PF01947.16 EIM86469.1 - 0.0086 16.1 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 p-hydroxybenzoic acid synthase Asp_Arg_Hydrox PF05118.15 EIM86469.1 - 0.0098 15.7 0.2 0.96 9.3 0.3 2.1 1 1 1 2 2 2 2 Aspartyl/Asparaginyl beta-hydroxylase CENP-T_C PF15511.6 EIM86471.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EIM86471.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EIM86471.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EIM86471.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM86471.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EIM86471.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EIM86472.1 - 1.9e-49 167.4 4.0 2.1e-49 167.2 4.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EIM86472.1 - 2.7e-05 24.5 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EIM86472.1 - 5.5e-05 23.2 0.1 0.0001 22.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EIM86472.1 - 0.00028 21.5 2.3 0.00035 21.2 2.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EIM86472.1 - 0.00071 19.8 0.1 0.0015 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EIM86472.1 - 0.09 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Pyr_redox_2 PF07992.14 EIM86473.1 - 5.9e-34 117.6 0.0 7.5e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM86473.1 - 3.6e-13 49.9 0.0 8.3e-11 42.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM86473.1 - 7.9e-08 32.3 2.1 0.00024 20.8 0.0 3.3 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM86473.1 - 2.2e-06 27.7 0.1 0.0023 17.9 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EIM86473.1 - 3.1e-05 23.4 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM86473.1 - 0.00027 19.9 0.7 0.0032 16.4 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EIM86473.1 - 0.0035 17.5 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM86473.1 - 0.0056 16.0 0.8 0.64 9.2 0.2 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EIM86473.1 - 0.0074 15.4 0.1 0.84 8.6 0.0 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 EIM86473.1 - 0.017 15.5 0.3 7.4 7.1 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EIM86473.1 - 0.02 13.6 0.1 0.98 8.0 0.0 2.6 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 EIM86473.1 - 0.061 12.6 0.5 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 EIM86473.1 - 0.061 13.6 0.0 5.9 7.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 EIM86473.1 - 0.65 9.0 4.5 1.4 7.9 0.1 2.8 4 0 0 4 4 4 0 Glucose inhibited division protein A Stathmin PF00836.19 EIM86474.1 - 0.03 14.3 0.3 0.066 13.2 0.3 1.6 1 0 0 1 1 1 0 Stathmin family Pirin PF02678.16 EIM86476.1 - 5.2e-28 97.2 0.3 9.2e-28 96.4 0.3 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EIM86476.1 - 6.8e-06 25.7 3.4 1.4e-05 24.7 0.9 2.2 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 EIM86476.1 - 0.0026 17.9 0.0 1.8 8.8 0.2 4.0 2 1 1 3 3 3 1 Quercetinase C-terminal cupin domain GPW_gp25 PF04965.14 EIM86477.1 - 0.11 12.2 0.0 0.45 10.3 0.0 2.0 1 0 0 1 1 1 0 Gene 25-like lysozyme Chromo_shadow PF01393.19 EIM86478.1 - 1.6e-11 44.1 0.9 3.1e-10 40.0 0.1 2.9 3 0 0 3 3 3 1 Chromo shadow domain Chromo PF00385.24 EIM86478.1 - 4.2e-11 42.6 0.4 4.2e-11 42.6 0.4 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SAP PF02037.27 EIM86479.1 - 3.5e-06 26.6 0.4 8.7e-06 25.4 0.4 1.7 1 0 0 1 1 1 1 SAP domain Bromo_TP PF07524.13 EIM86479.1 - 0.15 12.1 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Bromodomain associated zf-MYND PF01753.18 EIM86480.1 - 1.6e-09 37.7 10.7 2.7e-09 37.0 10.7 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EIM86480.1 - 1.3 9.1 6.1 2.9 8.1 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-TFIIIC PF12660.7 EIM86481.1 - 9.7e-23 80.0 0.1 2.1e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 EIM86481.1 - 1.3e-19 70.8 5.4 1.2e-17 64.4 2.0 2.4 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term ANAPC4_WD40 PF12894.7 EIM86481.1 - 0.00059 20.1 0.4 0.52 10.6 0.1 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Pro-kuma_activ PF09286.11 EIM86482.1 - 4.5e-33 114.5 0.0 2.4e-32 112.2 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM86482.1 - 0.0027 17.0 0.3 0.0027 17.0 0.3 2.3 2 1 1 3 3 3 1 Subtilase family Ish1 PF10281.9 EIM86482.1 - 0.045 14.1 0.0 0.19 12.0 0.0 2.0 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Arginosuc_synth PF00764.19 EIM86483.1 - 2.5e-149 497.8 0.0 3e-149 497.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EIM86483.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EIM86483.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase zf-RING_UBOX PF13445.6 EIM86484.1 - 4.8e-07 29.7 2.8 1.1e-06 28.6 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM86484.1 - 4.9e-07 29.5 2.6 4.9e-07 29.5 2.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM86484.1 - 2.3e-06 27.9 3.3 2.3e-06 27.9 3.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EIM86484.1 - 7.5e-06 25.8 5.9 1.4e-05 24.9 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIM86484.1 - 9.8e-06 25.3 9.4 6.4e-05 22.7 0.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM86484.1 - 3.8e-05 23.5 7.4 9.7e-05 22.2 7.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIM86484.1 - 4.1e-05 23.7 3.9 4.1e-05 23.7 3.9 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EIM86484.1 - 5.9e-05 22.9 0.7 0.00012 21.9 0.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein ATG16 PF08614.11 EIM86484.1 - 0.0004 20.7 3.1 0.00083 19.6 3.1 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Prok-RING_4 PF14447.6 EIM86484.1 - 0.00056 19.7 3.2 0.00056 19.7 3.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF724 PF05266.14 EIM86484.1 - 0.039 13.8 6.7 0.086 12.7 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_IE-1 PF05290.11 EIM86484.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1640 PF07798.11 EIM86484.1 - 0.13 12.3 3.5 0.2 11.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Spc7 PF08317.11 EIM86484.1 - 0.21 10.5 5.9 0.33 9.8 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_10 PF16685.5 EIM86484.1 - 0.22 11.7 1.8 0.42 10.8 1.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 TMPIT PF07851.13 EIM86484.1 - 0.41 9.8 4.7 0.59 9.3 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1732 PF08340.11 EIM86484.1 - 0.49 10.4 4.2 0.87 9.6 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Zn_ribbon_17 PF17120.5 EIM86484.1 - 0.96 9.1 6.8 0.15 11.7 1.0 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TMF_DNA_bd PF12329.8 EIM86484.1 - 0.99 9.4 15.2 0.15 12.1 7.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mt_ATP-synt_B PF05405.14 EIM86484.1 - 1.2 8.8 5.6 2.2 7.9 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-rbx1 PF12678.7 EIM86484.1 - 2.2 8.6 12.0 24 5.3 12.0 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain HIP1_clath_bdg PF16515.5 EIM86484.1 - 2.4 8.8 10.5 38 5.0 10.5 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RINGv PF12906.7 EIM86485.1 - 2e-15 56.6 7.8 3.9e-15 55.7 7.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EIM86485.1 - 0.02 15.2 9.3 0.032 14.6 9.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 EIM86485.1 - 2.3 8.3 4.7 4.5 7.4 4.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EIM86485.1 - 2.4 8.0 7.4 4.1 7.3 7.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NupH_GANP PF16768.5 EIM86486.1 - 0.039 13.7 0.5 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin homology of Germinal-centre associated nuclear protein HNH_2 PF13391.6 EIM86487.1 - 0.00043 20.3 0.9 0.0014 18.7 0.3 2.2 2 0 0 2 2 2 1 HNH endonuclease Peptidase_C15 PF01470.17 EIM86488.1 - 1.3e-08 35.3 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase Imm1 PF14430.6 EIM86488.1 - 0.069 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm1 Pkinase_fungal PF17667.1 EIM86489.1 - 7.8e-55 186.3 0.0 1e-54 185.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EIM86489.1 - 6.9e-07 28.9 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86489.1 - 0.0048 16.2 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM86489.1 - 0.074 13.0 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-MYND PF01753.18 EIM86491.1 - 1.8e-07 31.1 10.5 4.5e-07 29.8 10.5 1.7 1 0 0 1 1 1 1 MYND finger UbiA PF01040.18 EIM86493.1 - 2.6e-22 79.4 17.3 6.4e-22 78.1 16.3 1.8 1 1 1 2 2 2 2 UbiA prenyltransferase family RRM_1 PF00076.22 EIM86494.1 - 5.1e-15 55.0 0.0 8.2e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIM86494.1 - 0.029 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 EIM86494.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 EIM86495.1 - 2.5e-19 69.6 0.0 2e-18 66.8 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EIM86495.1 - 0.0032 17.3 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Oxidored_molyb PF00174.19 EIM86496.1 - 1.2e-48 164.9 0.0 3e-48 163.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EIM86496.1 - 5.9e-22 78.2 1.7 1.1e-21 77.2 1.7 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EIM86497.1 - 5.9e-48 162.7 0.0 1.4e-47 161.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EIM86497.1 - 1.8e-21 76.6 0.9 3.7e-21 75.6 0.9 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.25 EIM86499.1 - 7.6e-47 159.9 0.0 9.9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86499.1 - 4.4e-25 88.4 0.0 5.5e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM86499.1 - 2e-05 24.1 0.0 8.7e-05 22.0 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIM86499.1 - 0.0037 16.6 0.1 0.0062 15.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM86499.1 - 0.004 17.1 0.1 0.56 10.1 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 EIM86499.1 - 0.0078 15.8 0.3 0.024 14.2 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Cellulase PF00150.18 EIM86500.1 - 2.4e-13 50.1 1.2 3.9e-13 49.5 1.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PI3Ka PF00613.20 EIM86502.1 - 2.9e-53 180.0 0.4 4.9e-53 179.3 0.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EIM86502.1 - 1.7e-44 152.6 0.0 1.7e-41 142.7 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EIM86502.1 - 9.4e-40 135.8 0.0 1.6e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Red1 PF07964.11 EIM86503.1 - 5.1 5.2 11.5 0.14 10.4 2.8 1.9 2 0 0 2 2 2 0 Rec10 / Red1 RTC4 PF14474.6 EIM86504.1 - 1e-24 87.0 0.0 1.2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain Ribonuc_red_sm PF00268.21 EIM86506.1 - 2.5e-123 411.0 0.5 3e-123 410.7 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EIM86506.1 - 0.15 12.9 0.0 0.35 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) zf-MYND PF01753.18 EIM86507.1 - 1.8e-05 24.7 9.5 4.6e-05 23.4 9.5 1.8 1 0 0 1 1 1 1 MYND finger PTS_2-RNA PF01885.16 EIM86509.1 - 8.8e-63 211.6 0.1 1e-62 211.4 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Pirin PF02678.16 EIM86512.1 - 4.6e-12 45.9 0.0 7.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EIM86512.1 - 0.018 14.8 0.0 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Cupin domain Tmemb_170 PF10190.9 EIM86513.1 - 0.063 13.6 1.9 0.079 13.3 0.1 1.9 2 0 0 2 2 2 0 Putative transmembrane protein 170 DUF4679 PF15728.5 EIM86513.1 - 2 7.3 16.5 2.7 6.9 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) SET PF00856.28 EIM86515.1 - 1.9e-09 38.1 0.0 8.8e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 SET domain SET PF00856.28 EIM86516.1 - 9.2e-06 26.1 0.0 0.00048 20.6 0.0 2.6 1 1 1 2 2 2 2 SET domain Rtf2 PF04641.12 EIM86517.1 - 1.2 8.5 3.8 2.6 7.3 3.8 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger GATA PF00320.27 EIM86518.1 - 5e-14 51.6 2.3 1e-13 50.6 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF383 PF04063.14 EIM86519.1 - 4.5e-59 199.3 0.0 1.1e-58 198.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EIM86519.1 - 2e-21 75.6 0.0 7.4e-21 73.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF2183 PF09949.9 EIM86520.1 - 1.2e-29 102.5 0.0 2.4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) ATG16 PF08614.11 EIM86521.1 - 0.00079 19.7 34.6 0.005 17.1 15.6 3.9 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EIM86521.1 - 2 8.5 13.3 0.66 10.0 1.4 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EIM86521.1 - 2.9 8.3 30.8 4.9 7.5 8.5 3.6 2 1 1 3 3 3 0 Fez1 BST2 PF16716.5 EIM86521.1 - 8.2 7.1 20.6 6.1 7.5 1.8 4.2 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 DUF641 PF04859.12 EIM86521.1 - 8.3 6.8 17.5 1.2 9.5 5.1 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BTB PF00651.31 EIM86522.1 - 0.0065 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM86523.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 EIM86524.1 - 8.8e-48 162.4 0.0 1.5e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM86524.1 - 2.3e-31 108.4 0.0 7.1e-31 106.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EIM86524.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase EIIA-man PF03610.16 EIM86524.1 - 0.094 13.0 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 PTS system fructose IIA component ResIII PF04851.15 EIM86524.1 - 0.094 12.7 0.0 0.34 10.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit BTB PF00651.31 EIM86526.1 - 0.00015 22.0 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PBSX_XtrA PF17356.2 EIM86526.1 - 0.23 11.4 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA BTB PF00651.31 EIM86527.1 - 6.7e-06 26.3 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Stealth_CR3 PF17102.5 EIM86527.1 - 0.51 10.3 2.4 0.79 9.7 0.1 2.4 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 DPBB_1 PF03330.18 EIM86528.1 - 2.9e-06 27.4 0.5 6.6e-06 26.3 0.5 1.7 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM86528.1 - 0.013 15.4 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 Barwin family DUF2263 PF10021.9 EIM86530.1 - 5.4e-15 56.1 0.0 9.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.18 EIM86531.1 - 4.8e-22 78.2 0.0 9.8e-22 77.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EIM86532.1 - 2.1e-19 69.6 0.0 3.2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2207 PF09972.9 EIM86533.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OPT PF03169.15 EIM86534.1 - 6.3e-125 418.2 44.1 7.2e-125 418.0 44.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.18 EIM86535.1 - 1.8e-17 63.3 0.0 3.4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86535.1 - 2.7e-05 24.2 10.1 2.7e-05 24.2 10.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DegS PF05384.11 EIM86535.1 - 0.023 14.2 0.2 0.052 13.0 0.2 1.5 1 0 0 1 1 1 0 Sensor protein DegS AKNA PF12443.8 EIM86535.1 - 0.11 13.1 0.1 3.9 8.2 0.0 2.6 2 1 0 2 2 2 0 AT-hook-containing transcription factor RTA1 PF04479.13 EIM86536.1 - 5.6e-49 166.5 10.7 7.7e-49 166.1 10.7 1.2 1 0 0 1 1 1 1 RTA1 like protein MMR_HSR1 PF01926.23 EIM86537.1 - 7.9e-14 51.7 0.0 1.5e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EIM86537.1 - 0.0062 16.6 0.0 1.8 8.6 0.0 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EIM86537.1 - 0.026 14.4 0.0 0.1 12.5 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 EIM86537.1 - 0.051 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B WD40 PF00400.32 EIM86538.1 - 2.5e-62 205.3 21.8 8.7e-10 39.1 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM86538.1 - 2.1e-22 79.2 1.4 0.00098 19.4 0.0 6.1 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM86538.1 - 2.1e-10 40.8 0.1 4.1e-05 23.5 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EIM86538.1 - 6.1e-09 35.1 6.5 0.0051 15.5 0.1 5.0 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EIM86538.1 - 8e-08 31.6 4.5 0.21 10.5 0.0 4.5 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 EIM86538.1 - 0.00014 21.5 2.5 0.00067 19.3 0.6 2.5 1 1 2 3 3 3 1 Cytolethal distending toxin A/C domain DUF1513 PF07433.11 EIM86538.1 - 0.0002 20.5 0.7 2.6 7.1 0.0 3.3 2 2 1 3 3 3 2 Protein of unknown function (DUF1513) Pectate_lyase22 PF14583.6 EIM86538.1 - 0.00075 18.3 0.0 0.003 16.3 0.0 1.9 1 1 2 3 3 3 1 Oligogalacturonate lyase WD40_like PF17005.5 EIM86538.1 - 0.0013 18.1 0.1 0.92 8.8 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain RicinB_lectin_2 PF14200.6 EIM86538.1 - 0.0026 18.5 0.5 0.033 14.9 0.0 2.8 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Cytochrom_D1 PF02239.16 EIM86538.1 - 0.0073 14.9 0.0 0.049 12.2 0.0 2.2 1 1 0 2 2 2 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EIM86538.1 - 0.12 11.4 0.1 1.5 7.7 0.0 2.2 1 1 2 3 3 3 0 Coatomer WD associated region Kelch_6 PF13964.6 EIM86538.1 - 0.41 11.0 2.4 10 6.6 0.0 3.8 4 0 0 4 4 4 0 Kelch motif CLP1_P PF16575.5 EIM86540.1 - 1.9e-35 122.4 0.0 6.1e-35 120.7 0.0 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 EIM86540.1 - 0.045 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EIM86540.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EIM86540.1 - 0.19 11.8 0.1 0.56 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dicty_REP PF05086.12 EIM86540.1 - 3.5 5.5 3.5 4.8 5.0 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.32 EIM86541.1 - 5.8e-58 191.5 26.8 8.2e-09 36.0 0.2 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM86541.1 - 9.7e-23 80.3 0.9 0.0019 18.5 0.1 5.8 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EIM86541.1 - 3.8e-09 36.9 0.0 6.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EIM86541.1 - 5.5e-08 31.9 2.8 0.00073 18.3 0.0 3.6 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EIM86541.1 - 0.00016 20.8 0.0 2.3 7.1 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 EIM86541.1 - 0.0075 15.9 0.2 3.6 7.4 0.1 2.9 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature PD40 PF07676.12 EIM86541.1 - 0.023 14.6 0.1 3.7 7.6 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EIM86541.1 - 0.046 11.7 0.0 0.073 11.1 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Nucleoporin_N PF08801.11 EIM86541.1 - 0.12 11.1 2.9 3.4 6.3 0.3 3.6 3 1 0 3 3 3 0 Nup133 N terminal like RAB3GAP2_N PF14655.6 EIM86541.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RabGAP-TBC PF00566.18 EIM86543.1 - 1.3e-42 145.9 0.0 2.2e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 EIM86543.1 - 9.1e-05 22.8 1.6 0.0011 19.4 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EIM86543.1 - 0.00016 21.0 1.5 0.001 18.5 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EIM86543.1 - 0.00019 21.1 4.2 0.0014 18.4 0.5 3.0 2 0 0 2 2 2 1 EF-hand domain GRAM PF02893.20 EIM86543.1 - 0.0038 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.6 EIM86543.1 - 0.056 13.0 0.1 0.16 11.5 0.1 1.8 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.9 EIM86543.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region MFS_1 PF07690.16 EIM86546.1 - 6.4e-32 110.8 39.2 6.4e-32 110.8 39.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2183 PF09949.9 EIM86547.1 - 1e-15 57.8 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) BTB PF00651.31 EIM86548.1 - 1.9e-06 28.0 0.1 5.8e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM86549.1 - 3.7e-08 33.6 0.0 5.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DNA_pol_B PF00136.21 EIM86550.1 - 4.5e-118 394.9 0.0 6.2e-118 394.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EIM86550.1 - 5.8e-61 205.5 0.0 9.6e-61 204.8 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EIM86550.1 - 1.2e-25 90.4 0.0 2.4e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EIM86550.1 - 2.3e-19 69.2 7.7 6.4e-19 67.8 7.7 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EIM86550.1 - 0.018 13.9 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral CAP_N PF01213.19 EIM86550.1 - 0.11 12.0 0.9 0.23 10.9 0.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Flavin_Reduct PF01613.18 EIM86551.1 - 1e-28 100.3 0.1 1.4e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain zf-DNL PF05180.12 EIM86554.1 - 1.2e-29 102.0 0.3 2e-29 101.3 0.3 1.3 1 0 0 1 1 1 1 DNL zinc finger Glutaredoxin PF00462.24 EIM86555.1 - 1.3e-15 57.4 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Sds3 PF08598.11 EIM86556.1 - 3.3e-09 37.1 0.0 5.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Sds3-like AICARFT_IMPCHas PF01808.18 EIM86557.1 - 2.6e-84 283.2 0.0 3.5e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme adh_short PF00106.25 EIM86557.1 - 3.3e-37 127.8 0.0 5.1e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM86557.1 - 5.9e-29 101.3 0.0 1.1e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MGS PF02142.22 EIM86557.1 - 8.9e-24 83.5 0.0 2.3e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 MGS-like domain KR PF08659.10 EIM86557.1 - 3.5e-08 33.6 0.0 8.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EIM86557.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM86557.1 - 0.1 12.5 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H-binding Ribosomal_L3 PF00297.22 EIM86557.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L3 F-box-like PF12937.7 EIM86558.1 - 0.00013 21.8 0.0 0.00056 19.7 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM86559.1 - 0.00014 21.6 0.1 0.0006 19.7 0.1 2.1 1 1 0 1 1 1 1 F-box-like TPR_MLP1_2 PF07926.12 EIM86559.1 - 0.02 15.0 4.4 0.033 14.3 4.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ABM PF03992.16 EIM86562.1 - 9.9e-11 41.6 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ACC_central PF08326.12 EIM86563.1 - 1.3e-245 817.1 0.0 2e-245 816.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EIM86563.1 - 2.8e-170 567.2 0.0 3.7e-170 566.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EIM86563.1 - 2.2e-50 171.1 0.0 4.2e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EIM86563.1 - 1.3e-29 103.0 0.0 2.6e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EIM86563.1 - 3.7e-21 75.2 0.0 5.4e-20 71.5 0.0 2.9 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EIM86563.1 - 1.8e-14 53.3 0.0 3.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EIM86563.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EIM86563.1 - 0.022 14.3 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EIM86563.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 EIM86563.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Kinesin PF00225.23 EIM86564.1 - 3.1e-102 341.9 0.3 4.8e-102 341.3 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIM86564.1 - 1.6e-58 196.8 0.0 4.8e-58 195.3 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding TPR_MLP1_2 PF07926.12 EIM86564.1 - 4.1e-05 23.6 11.3 4.1e-05 23.6 11.3 2.9 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein LPP PF04728.13 EIM86564.1 - 0.0013 19.1 4.4 0.75 10.2 0.4 4.3 3 1 0 3 3 3 1 Lipoprotein leucine-zipper SHE3 PF17078.5 EIM86564.1 - 0.0034 17.1 10.7 0.011 15.5 10.7 1.9 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 AAA_13 PF13166.6 EIM86564.1 - 0.0091 14.7 10.7 0.022 13.5 10.7 1.6 1 0 0 1 1 1 1 AAA domain Tropomyosin_1 PF12718.7 EIM86564.1 - 0.023 14.8 14.7 0.23 11.6 0.8 2.9 2 1 0 2 2 2 0 Tropomyosin like Ham1p_like PF01725.16 EIM86564.1 - 0.046 13.6 0.4 0.14 12.1 0.3 2.0 1 1 0 1 1 1 0 Ham1 family ATG16 PF08614.11 EIM86564.1 - 0.16 12.2 30.9 2.5 8.3 9.4 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) WXG100 PF06013.12 EIM86564.1 - 0.21 11.8 11.6 0.032 14.4 3.0 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Filament PF00038.21 EIM86564.1 - 0.23 11.0 23.4 0.14 11.7 7.5 2.6 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 EIM86564.1 - 0.55 9.1 27.1 0.17 10.8 16.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF5082 PF16888.5 EIM86564.1 - 0.67 10.2 13.1 5.7 7.2 3.1 2.9 2 1 0 3 3 2 0 Domain of unknown function (DUF5082) Fzo_mitofusin PF04799.13 EIM86564.1 - 0.91 9.1 12.6 0.66 9.5 3.0 2.9 1 1 2 3 3 3 0 fzo-like conserved region NPV_P10 PF05531.12 EIM86564.1 - 0.92 10.0 5.4 6.7 7.3 0.3 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 EIM86564.1 - 1.1 9.2 11.5 5.2 7.1 1.7 3.8 4 0 0 4 4 4 0 Prefoldin subunit BRE1 PF08647.11 EIM86564.1 - 1.4 9.1 18.7 0.065 13.3 4.7 3.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase MAD PF05557.13 EIM86564.1 - 1.9 6.7 23.3 6.9 4.9 23.3 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.12 EIM86564.1 - 2 8.4 7.4 2.1 8.4 2.7 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 EIM86564.1 - 2.5 8.2 24.3 0.27 11.3 6.5 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EIM86564.1 - 3 8.5 22.5 8.7 7.0 2.3 5.7 4 1 2 6 6 6 0 Initiation control protein YabA DUF16 PF01519.16 EIM86564.1 - 4.7 7.8 12.4 2.6 8.6 2.0 3.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EIM86564.1 - 5.2 7.3 15.0 1.9 8.7 3.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 EIM86564.1 - 5.7 7.0 11.4 4.7 7.3 5.1 3.6 3 1 0 3 3 3 0 FlxA-like protein HAP1_N PF04849.13 EIM86564.1 - 6.1 6.0 22.9 0.23 10.6 11.6 2.5 1 1 0 2 2 2 0 HAP1 N-terminal conserved region UPF0242 PF06785.11 EIM86564.1 - 6.9 6.7 25.1 0.59 10.2 9.9 2.7 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 EIM86564.1 - 8.7 6.7 27.0 1.9 8.9 16.7 2.7 1 1 1 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 EIM86564.1 - 8.7 6.6 25.6 7.5 6.8 5.2 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Peptidase_C14 PF00656.22 EIM86565.1 - 5.3e-21 75.7 0.0 8.5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_M20 PF01546.28 EIM86566.1 - 3.2e-28 98.9 0.0 4.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM86566.1 - 3.1e-11 43.1 0.0 7.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM86566.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DAP3 PF10236.9 EIM86567.1 - 1.1e-68 231.7 0.0 1.5e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EIM86567.1 - 1.4e-06 28.8 0.0 2.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EIM86567.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_35 PF14516.6 EIM86567.1 - 0.16 10.8 0.0 2.7 6.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain VHS PF00790.19 EIM86568.1 - 8.6e-33 113.2 0.1 1.8e-32 112.1 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_2 PF07653.17 EIM86568.1 - 1.5e-14 53.4 0.1 3.4e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIM86568.1 - 2.7e-14 52.5 0.0 4.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIM86568.1 - 5.8e-14 51.7 0.1 9.8e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EIM86568.1 - 6.4e-13 48.8 0.9 1.8e-12 47.3 0.9 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 EIM86568.1 - 0.014 15.3 2.4 0.036 14.0 2.4 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF4763 PF15960.5 EIM86568.1 - 0.056 12.8 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CRM1_C PF08767.11 EIM86568.1 - 0.097 11.8 0.1 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 CRM1 C terminal RmuC PF02646.16 EIM86568.1 - 0.18 10.9 1.0 0.27 10.3 0.2 1.6 2 0 0 2 2 2 0 RmuC family UQ_con PF00179.26 EIM86569.1 - 6.6e-17 61.5 0.0 7e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EIM86569.1 - 0.0073 16.6 0.0 0.0077 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EIM86569.1 - 0.049 13.5 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain Asp PF00026.23 EIM86570.1 - 5.5e-75 252.7 14.4 7.1e-75 252.3 14.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM86570.1 - 8.1e-09 36.0 12.9 0.00027 21.2 4.6 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EIM86570.1 - 0.0012 18.6 0.3 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Opi1 PF08618.10 EIM86571.1 - 4.7e-115 385.2 22.0 4.7e-115 385.2 22.0 3.1 2 1 0 2 2 2 1 Transcription factor Opi1 Perilipin PF03036.16 EIM86571.1 - 7.3e-06 25.2 0.0 1.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Perilipin family REF PF05755.12 EIM86571.1 - 0.038 13.8 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) zf-MYND PF01753.18 EIM86572.1 - 2.3e-11 43.6 8.5 6.5e-11 42.1 8.5 1.8 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EIM86572.1 - 0.0005 20.1 1.3 0.0005 20.1 1.3 1.7 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EIM86572.1 - 0.0055 17.0 4.7 0.0055 17.0 4.7 2.2 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Tnp_zf-ribbon_2 PF13842.6 EIM86572.1 - 1.2 10.0 11.0 6 7.8 1.8 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2_3 PF13878.6 EIM86572.1 - 1.7 8.5 7.8 0.089 12.6 1.2 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Ribosomal_L35Ae PF01247.18 EIM86573.1 - 9.4e-45 150.7 0.6 1e-44 150.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EIM86573.1 - 0.00048 20.3 0.0 0.69 10.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain ArgJ PF01960.18 EIM86574.1 - 1.6e-139 464.8 0.0 1.9e-139 464.6 0.0 1.0 1 0 0 1 1 1 1 ArgJ family F-box-like PF12937.7 EIM86575.1 - 2.8e-08 33.5 1.4 8.9e-08 31.9 0.8 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM86575.1 - 0.63 10.6 4.0 19 5.9 0.1 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.23 EIM86576.1 - 3.6e-08 33.2 0.2 3.2e-07 30.1 0.2 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EIM86576.1 - 2.3e-06 27.6 5.1 0.00024 21.2 0.3 2.5 2 0 0 2 2 2 2 GRF zinc finger Spuma_A9PTase PF03539.14 EIM86576.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Exo_endo_phos_2 PF14529.6 EIM86576.1 - 0.062 13.2 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase zf-C2H2_jaz PF12171.8 EIM86577.1 - 6.1e-10 39.1 3.8 1.1e-09 38.4 3.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EIM86577.1 - 0.043 14.1 2.0 0.043 14.1 2.0 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EIM86577.1 - 0.061 13.7 2.9 0.11 12.9 2.9 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type IQ PF00612.27 EIM86577.1 - 4.8 7.3 7.3 2.1 8.4 0.7 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif DNA_pol_A_exo1 PF01612.20 EIM86578.1 - 1.1e-13 51.2 0.0 2.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Rubi_NSP_C PF12601.8 EIM86578.1 - 0.011 15.8 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Rubivirus non-structural protein DNA_pol_A_exo1 PF01612.20 EIM86579.1 - 4.5e-13 49.3 0.1 4.5e-12 46.0 0.1 2.0 1 1 0 1 1 1 1 3'-5' exonuclease LpxI_N PF17930.1 EIM86579.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 LpxI N-terminal domain Oxidored_molyb PF00174.19 EIM86580.1 - 6.7e-56 188.6 0.0 1e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EIM86580.1 - 2e-07 31.1 0.0 7.7e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain GATA PF00320.27 EIM86581.1 - 1.4e-17 62.9 3.4 2.3e-17 62.3 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EIM86581.1 - 0.0051 16.3 1.0 0.0085 15.6 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.18 EIM86581.1 - 0.0095 16.0 0.2 0.011 15.8 0.2 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ephrin_rec_like PF07699.13 EIM86581.1 - 0.026 14.3 0.7 4.6 7.1 0.2 2.2 2 0 0 2 2 2 0 Putative ephrin-receptor like Auto_anti-p27 PF06677.12 EIM86581.1 - 0.029 14.5 0.4 0.042 14.0 0.4 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 EIM86581.1 - 0.032 13.7 3.0 1.5 8.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EIM86581.1 - 0.08 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain GATA PF00320.27 EIM86582.1 - 1.1e-11 44.2 5.6 1.5e-11 43.7 5.6 1.2 1 0 0 1 1 1 1 GATA zinc finger zf-ribbon_3 PF13248.6 EIM86582.1 - 0.038 13.4 5.4 0.096 12.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EIM86582.1 - 0.041 14.1 0.5 0.059 13.5 0.5 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 EIM86582.1 - 0.041 14.0 0.6 0.089 12.9 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-RRN7 PF11781.8 EIM86582.1 - 0.25 11.1 1.9 0.55 10.0 1.9 1.5 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Amidohydro_3 PF07969.11 EIM86583.1 - 1.3e-15 57.8 0.5 1.6e-10 41.1 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EIM86583.1 - 2.6e-14 53.3 0.0 2.8e-11 43.4 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Zds_C PF08632.10 EIM86586.1 - 5.1e-28 96.6 1.1 9.5e-28 95.7 1.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term LEA_3 PF03242.13 EIM86586.1 - 0.94 10.2 0.0 0.94 10.2 0.0 3.3 3 1 0 3 3 3 0 Late embryogenesis abundant protein Vfa1 PF08432.10 EIM86586.1 - 8.1 6.7 17.7 8.1 6.7 3.6 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Cys_Met_Meta_PP PF01053.20 EIM86587.1 - 3.2e-136 453.9 0.0 3.6e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EIM86587.1 - 8.9e-11 41.6 0.1 1.6e-10 40.7 0.1 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIM86587.1 - 2.1e-10 40.5 0.5 3.5e-10 39.7 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EIM86587.1 - 2.3e-09 36.7 0.7 5e-09 35.6 0.7 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EIM86587.1 - 0.00015 21.2 0.0 0.00042 19.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EIM86587.1 - 0.0061 15.1 0.1 0.0078 14.8 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 EIM86587.1 - 0.065 13.5 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain Amnionless PF14828.6 EIM86588.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2781 PF10914.8 EIM86589.1 - 1.4e-35 122.8 11.8 1.6e-35 122.6 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Peptidase_M56 PF05569.11 EIM86590.1 - 0.18 11.0 0.1 0.25 10.5 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 PH_10 PF15411.6 EIM86591.1 - 1.1e-23 83.9 0.0 1.9e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EIM86591.1 - 4.2e-05 23.9 0.0 0.00012 22.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EIM86591.1 - 0.00023 21.4 2.1 0.00066 20.0 2.2 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM86591.1 - 0.00051 20.0 2.5 0.0014 18.6 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIM86591.1 - 0.001 19.0 0.2 0.0024 17.8 0.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain VWA_3 PF13768.6 EIM86591.1 - 0.001 19.0 0.0 0.0039 17.1 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_11 PF17123.5 EIM86591.1 - 0.095 12.5 2.7 0.31 10.8 2.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 EIM86591.1 - 0.21 11.5 0.1 0.5 10.3 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM86591.1 - 0.66 9.9 2.5 3.4 7.6 2.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dynactin_p22 PF07426.11 EIM86592.1 - 2.6e-18 66.4 0.0 1.3e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 Dynactin subunit p22 Lebercilin PF15619.6 EIM86592.1 - 0.00037 20.2 2.5 0.00093 18.9 2.5 1.7 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Nsp1_C PF05064.13 EIM86592.1 - 0.022 14.5 1.0 11 5.8 0.1 3.3 3 1 0 3 3 3 0 Nsp1-like C-terminal region DUF4600 PF15372.6 EIM86592.1 - 0.043 14.2 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) AAA_12 PF13087.6 EIM86593.1 - 5.4e-37 127.3 0.0 1.4e-36 126.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM86593.1 - 9.6e-27 94.4 0.0 7.6e-26 91.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM86593.1 - 1.7e-10 40.9 0.1 3.4e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EIM86593.1 - 1.1e-09 38.8 0.0 1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EIM86593.1 - 0.00054 19.3 0.0 0.021 14.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EIM86593.1 - 0.08 12.9 0.1 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EIM86593.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 EIM86593.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EIM86593.1 - 0.13 12.8 0.0 0.48 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EIM86593.1 - 0.15 12.5 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-CCCH PF00642.24 EIM86593.1 - 0.29 11.1 3.8 0.82 9.7 3.8 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EIM86593.1 - 0.39 11.4 1.3 0.82 10.4 0.1 2.1 2 0 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 EIM86593.1 - 0.51 10.5 3.3 1.2 9.3 3.3 1.7 1 0 0 1 1 1 0 Zinc finger domain E1-E2_ATPase PF00122.20 EIM86594.1 - 6.4e-49 165.9 3.2 1.7e-48 164.6 3.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EIM86594.1 - 5.5e-31 108.5 2.8 8.1e-31 108.0 1.2 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EIM86594.1 - 3e-26 91.6 0.0 1.6e-13 50.8 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EIM86594.1 - 4.3e-05 23.4 0.3 0.0072 16.1 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Peptidase_M91 PF14891.6 EIM86595.1 - 0.13 12.6 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Effector protein Aldedh PF00171.22 EIM86596.1 - 6.9e-13 47.9 5.6 1.3e-09 37.1 4.6 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family SHNi-TPR PF10516.9 EIM86597.1 - 5.8e-13 48.1 0.0 6.4e-11 41.5 0.0 2.6 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 EIM86597.1 - 1.4e-09 38.1 13.1 0.00031 21.0 1.7 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86597.1 - 8.8e-05 22.2 2.2 0.16 11.8 0.5 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM86597.1 - 0.00049 20.0 8.6 0.32 11.2 0.9 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM86597.1 - 0.064 13.5 7.5 13 6.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIM86597.1 - 0.16 12.5 0.1 0.16 12.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Atg14 PF10186.9 EIM86597.1 - 0.16 11.0 1.9 0.25 10.4 1.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNAP PF14938.6 EIM86597.1 - 0.28 10.6 7.5 0.086 12.3 1.8 2.2 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 EIM86597.1 - 2.4 7.9 6.3 2.1 8.1 0.1 3.6 4 1 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 EIM86597.1 - 2.6 8.8 18.2 4 8.2 0.2 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM86597.1 - 6.5 7.0 6.1 2.9 8.1 0.2 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.7 EIM86598.1 - 0.00049 20.4 0.3 6.3 7.4 0.0 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) SPX PF03105.19 EIM86600.1 - 1.7 8.5 6.2 3 7.7 6.2 1.3 1 0 0 1 1 1 0 SPX domain MS_channel PF00924.18 EIM86601.1 - 1.9e-18 66.7 2.3 3.6e-18 65.8 2.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EIM86601.1 - 6.1e-06 25.4 0.1 1.4e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EIM86601.1 - 3.1e-05 23.5 0.0 9.7e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EIM86601.1 - 0.00094 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair PBP1_TM PF14812.6 EIM86601.1 - 0.0025 18.1 1.2 0.011 16.1 0.1 2.4 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_5 PF13202.6 EIM86601.1 - 0.003 17.0 0.1 0.0088 15.5 0.1 1.8 1 0 0 1 1 1 1 EF hand ABC_membrane PF00664.23 EIM86602.1 - 2.4e-72 243.9 34.9 1.1e-36 126.9 14.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM86602.1 - 6e-52 175.8 0.0 6.6e-31 107.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EIM86602.1 - 1.2e-08 34.7 0.0 0.0082 15.6 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EIM86602.1 - 7.4e-05 22.8 0.7 0.5 10.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EIM86602.1 - 0.00021 21.0 0.3 0.061 13.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EIM86602.1 - 0.0012 19.3 0.1 0.52 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EIM86602.1 - 0.0051 16.1 0.0 0.52 9.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 EIM86602.1 - 0.0081 16.1 0.6 4.6 7.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF4574 PF15141.6 EIM86602.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Dynamin_N PF00350.23 EIM86602.1 - 0.022 14.8 3.8 2.2 8.3 0.1 2.8 3 0 0 3 3 3 0 Dynamin family AAA_21 PF13304.6 EIM86602.1 - 0.026 14.3 1.7 3.9 7.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIM86602.1 - 0.031 14.8 0.1 4.9 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TMEM126 PF07114.11 EIM86602.1 - 0.039 13.4 0.5 0.11 11.9 0.5 1.7 1 0 0 1 1 1 0 Transmembrane protein 126 AAA_22 PF13401.6 EIM86602.1 - 0.041 14.2 2.3 2.8 8.2 0.2 3.4 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EIM86602.1 - 0.15 11.7 2.2 1 8.9 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EIM86602.1 - 0.31 11.1 4.7 2.5 8.1 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Peptidase_C12 PF01088.21 EIM86603.1 - 2e-55 187.8 0.0 2.4e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Hamartin PF04388.12 EIM86604.1 - 5.1 5.6 7.4 4.9 5.7 7.4 1.0 1 0 0 1 1 1 0 Hamartin protein NAD_binding_8 PF13450.6 EIM86605.1 - 3.4e-09 36.8 0.0 7.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIM86605.1 - 8.8e-09 35.2 0.0 1.8e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EIM86605.1 - 7.8e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM86605.1 - 0.00033 20.0 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM86605.1 - 0.00035 19.4 0.1 0.00067 18.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM86605.1 - 0.00046 19.5 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM86605.1 - 0.0018 17.5 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EIM86605.1 - 0.0035 16.5 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UPF0180 PF03698.13 EIM86605.1 - 0.012 15.8 0.0 0.13 12.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) DAO PF01266.24 EIM86605.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM86605.1 - 0.091 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EIM86605.1 - 0.099 12.6 0.2 1 9.3 0.0 2.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding Epimerase PF01370.21 EIM86606.1 - 2.1e-19 69.9 0.2 5.3e-19 68.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM86606.1 - 3.4e-09 36.6 0.0 1.2e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM86606.1 - 1.4e-07 31.0 0.1 4.9e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EIM86606.1 - 2.1e-07 31.0 0.7 3.1e-07 30.5 0.3 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIM86606.1 - 5.8e-07 28.8 0.1 1.9e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EIM86606.1 - 0.0097 15.1 0.1 0.02 14.0 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EIM86606.1 - 0.016 14.7 1.1 0.02 14.4 0.1 1.8 2 1 0 2 2 2 0 short chain dehydrogenase DUF1640 PF07798.11 EIM86607.1 - 1.3e-59 201.2 8.9 1.6e-59 200.8 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DotU PF09850.9 EIM86607.1 - 0.012 15.3 2.1 2.9 7.5 0.6 2.5 2 1 0 2 2 2 0 Type VI secretion system protein DotU KIAA1430 PF13879.6 EIM86607.1 - 0.11 13.3 5.2 0.26 12.1 5.2 1.7 1 0 0 1 1 1 0 KIAA1430 homologue BshC PF10079.9 EIM86607.1 - 0.16 10.6 4.7 0.21 10.3 4.7 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Uso1_p115_C PF04871.13 EIM86607.1 - 0.95 9.8 10.6 0.11 12.9 4.5 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Guanylate_kin PF00625.21 EIM86608.1 - 1.7e-62 210.3 0.0 2.1e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EIM86608.1 - 7.5e-09 36.2 0.0 2.3e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EIM86608.1 - 0.00024 21.3 0.0 0.0011 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EIM86608.1 - 0.00048 20.2 0.0 0.0011 19.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EIM86608.1 - 0.00053 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EIM86608.1 - 0.0028 17.6 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 EIM86608.1 - 0.0037 17.8 0.0 0.0068 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EIM86608.1 - 0.0038 17.1 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 EIM86608.1 - 0.0071 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 EIM86608.1 - 0.0086 16.6 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EIM86608.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EIM86608.1 - 0.013 14.7 0.0 0.31 10.2 0.0 2.0 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 EIM86608.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EIM86608.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EIM86608.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EIM86608.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EIM86608.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EIM86608.1 - 0.031 14.0 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EIM86608.1 - 0.031 14.7 0.0 0.092 13.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EIM86608.1 - 0.048 13.6 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EIM86608.1 - 0.092 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EIM86608.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 EIM86608.1 - 0.24 10.8 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Pkinase PF00069.25 EIM86609.1 - 5.2e-64 216.1 0.0 7.3e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86609.1 - 9.4e-36 123.4 0.0 1.3e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM86609.1 - 1.3e-07 31.2 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM86609.1 - 0.00079 19.4 0.3 0.0017 18.3 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM86609.1 - 0.0042 15.9 0.0 0.0074 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EIM86609.1 - 0.05 12.5 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DNA_ligase_A_M PF01068.21 EIM86610.1 - 2.2e-24 86.3 0.0 3.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIM86610.1 - 1.2e-11 45.3 0.0 2.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EIM86610.1 - 0.001 19.4 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EIM86610.1 - 0.012 16.2 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region SAICAR_synt PF01259.18 EIM86611.1 - 3.6e-83 279.1 0.0 1.6e-43 149.2 0.0 2.1 1 1 1 2 2 2 2 SAICAR synthetase zf-ZPR1 PF03367.13 EIM86612.1 - 1.9e-109 362.6 0.1 2.2e-54 183.6 0.0 3.1 2 1 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.10 EIM86612.1 - 0.0012 18.9 0.5 3 8.0 0.1 3.1 2 1 0 2 2 2 2 Zinc ribbon domain HypA PF01155.19 EIM86612.1 - 0.0084 16.1 1.4 2.2 8.3 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2688 PF10892.8 EIM86612.1 - 0.078 12.4 1.3 0.85 9.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) OrfB_Zn_ribbon PF07282.11 EIM86612.1 - 0.15 12.0 2.0 36 4.4 0.0 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.7 EIM86612.1 - 0.31 11.1 5.8 0.9 9.6 0.1 3.0 2 1 1 3 3 3 0 Double zinc ribbon Rubredoxin_2 PF18073.1 EIM86612.1 - 0.52 10.1 8.1 2.2 8.1 0.4 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain UPF0547 PF10571.9 EIM86612.1 - 7.1 6.8 6.9 69 3.6 0.4 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Nup35_RRM PF05172.13 EIM86613.1 - 7.8e-10 38.6 0.0 2.7e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EIM86613.1 - 0.0027 17.7 0.1 0.012 15.6 0.1 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif UAA PF08449.11 EIM86614.1 - 9.4e-75 251.6 9.8 1.1e-74 251.4 9.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EIM86614.1 - 0.025 13.9 4.6 1 8.7 0.5 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.20 EIM86614.1 - 0.083 13.1 22.0 0.99 9.6 7.2 3.2 2 2 0 2 2 2 0 EamA-like transporter family Phage_holin_Dp1 PF16938.5 EIM86614.1 - 0.35 11.1 1.9 0.96 9.7 0.3 2.3 2 0 0 2 2 2 0 Putative phage holin Dp-1 PUNUT PF16913.5 EIM86614.1 - 0.41 9.8 17.7 0.018 14.3 3.7 2.4 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport CAP_N PF01213.19 EIM86614.1 - 2.7 7.4 6.1 4.9 6.6 6.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3446 PF11928.8 EIM86614.1 - 9 6.7 24.2 0.43 10.9 2.0 3.3 3 1 1 4 4 4 0 Early growth response N-terminal domain Ribosomal_L28e PF01778.17 EIM86615.1 - 2.5e-37 128.1 2.1 2.5e-37 128.1 2.1 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EIM86615.1 - 1.6e-27 96.0 18.1 1.6e-27 96.0 18.1 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.18 EIM86615.1 - 0.14 11.9 1.3 0.22 11.2 1.3 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain DUF2722 PF10846.8 EIM86615.1 - 0.25 10.2 5.9 0.36 9.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 EIM86615.1 - 1.2 8.4 24.9 1.7 8.0 24.9 1.3 1 0 0 1 1 1 0 SDA1 Latrophilin PF02354.16 EIM86615.1 - 2.4 7.1 8.4 2.4 7.1 3.0 2.1 2 0 0 2 2 2 0 Latrophilin Cytoplasmic C-terminal region RRN3 PF05327.11 EIM86615.1 - 3.5 6.0 14.3 5.2 5.5 14.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DEAD PF00270.29 EIM86616.1 - 6e-41 140.1 0.3 9.1e-41 139.5 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM86616.1 - 3.2e-28 98.3 0.0 1.3e-27 96.3 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM86616.1 - 1.1e-06 28.8 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 EIM86616.1 - 0.04 12.2 0.3 0.051 11.9 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SWIRM-assoc_2 PF16496.5 EIM86616.1 - 0.11 11.3 3.3 0.18 10.6 3.3 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CMS1 PF14617.6 EIM86616.1 - 0.12 11.7 0.8 0.38 10.0 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FlgM PF04316.13 EIM86616.1 - 0.13 12.7 0.2 0.38 11.2 0.2 1.8 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Apt1 PF10351.9 EIM86616.1 - 0.14 10.9 2.2 0.22 10.3 2.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NACHT PF05729.12 EIM86617.1 - 1e-10 41.8 0.8 1.9e-10 40.9 0.1 1.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EIM86617.1 - 0.00055 20.4 0.4 0.0027 18.1 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EIM86617.1 - 0.0011 18.2 0.4 0.0036 16.5 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 EIM86617.1 - 0.0046 17.2 0.1 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIM86617.1 - 0.0066 16.8 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.9 EIM86617.1 - 0.018 14.3 0.2 0.047 12.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EIM86617.1 - 0.025 15.0 0.7 0.65 10.4 0.0 3.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EIM86617.1 - 0.031 14.7 0.3 0.71 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EIM86617.1 - 0.035 14.4 0.0 0.16 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EIM86617.1 - 0.055 13.4 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Coq4 PF05019.13 EIM86617.1 - 0.1 11.9 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ATPase PF06745.13 EIM86617.1 - 0.22 10.9 1.9 1.6 8.0 0.0 2.6 3 0 0 3 3 3 0 KaiC Peptidase_S10 PF00450.22 EIM86617.1 - 0.32 10.3 1.8 0.49 9.7 0.4 1.8 1 1 1 2 2 2 0 Serine carboxypeptidase Ank_4 PF13637.6 EIM86618.1 - 0.062 13.9 0.0 0.077 13.6 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM86618.1 - 0.093 13.3 0.0 0.093 13.3 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIM86618.1 - 0.12 13.0 0.0 0.22 12.2 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeat Mito_carr PF00153.27 EIM86620.1 - 6.3e-62 205.5 1.3 2e-22 78.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rbc25 PF08292.12 EIM86621.1 - 2e-30 105.7 0.1 3.9e-30 104.7 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EIM86621.1 - 2.4e-21 75.9 0.0 3.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PET117 PF15786.5 EIM86622.1 - 4.4e-26 91.0 5.1 5e-26 90.8 5.1 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial MAS20 PF02064.15 EIM86622.1 - 0.00078 19.5 1.1 0.00088 19.4 1.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF4355 PF14265.6 EIM86622.1 - 0.0078 16.4 1.4 0.0091 16.2 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) DUF4500 PF14937.6 EIM86622.1 - 0.038 14.0 0.2 0.07 13.1 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4500) F-box-like PF12937.7 EIM86623.1 - 2e-11 43.6 0.3 4.8e-11 42.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM86623.1 - 0.0004 20.2 0.1 0.00074 19.3 0.1 1.4 1 0 0 1 1 1 1 F-box domain ERG4_ERG24 PF01222.17 EIM86624.1 - 1.3e-133 445.9 24.2 1.5e-133 445.7 24.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIM86624.1 - 8.4e-07 28.7 3.2 1.8e-06 27.7 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EIM86624.1 - 0.022 15.2 1.3 0.34 11.4 0.1 2.8 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FAD_binding_3 PF01494.19 EIM86625.1 - 3.5e-24 85.7 1.6 3.6e-15 56.1 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 EIM86625.1 - 3.7e-09 36.1 0.1 8.6e-05 21.7 0.0 2.9 3 1 1 4 4 4 2 Lycopene cyclase protein Trp_halogenase PF04820.14 EIM86625.1 - 3.8e-06 26.0 0.1 0.024 13.5 0.2 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EIM86625.1 - 1.1e-05 24.9 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EIM86625.1 - 4.1e-05 22.8 0.0 6.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 EIM86625.1 - 8.6e-05 23.0 0.0 0.2 12.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM86625.1 - 0.00012 21.8 0.1 0.021 14.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM86625.1 - 0.0011 19.0 0.1 0.0038 17.2 0.1 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EIM86625.1 - 0.0027 16.5 0.0 0.054 12.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EIM86625.1 - 0.017 14.3 0.1 0.052 12.8 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EIM86625.1 - 0.023 13.8 1.5 0.21 10.6 0.7 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EIM86625.1 - 0.03 14.6 0.2 0.03 14.6 0.2 2.2 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EIM86625.1 - 0.046 12.8 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EIM86625.1 - 0.084 12.1 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CRISPR_assoc PF08798.11 EIM86625.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Sec6 PF06046.13 EIM86626.1 - 2.4e-155 518.2 4.6 2.4e-155 518.2 4.6 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF3289 PF11692.8 EIM86626.1 - 0.00053 19.7 1.0 0.0055 16.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3289) HECT PF00632.25 EIM86626.1 - 0.02 14.4 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) ACDC PF14733.6 EIM86626.1 - 0.024 14.9 0.0 0.13 12.6 0.0 2.3 1 0 0 1 1 1 0 AP2-coincident C-terminal Bromo_TP PF07524.13 EIM86626.1 - 0.025 14.6 0.2 26 4.9 0.0 4.0 2 1 1 3 3 3 0 Bromodomain associated SKA2 PF16740.5 EIM86626.1 - 0.028 14.2 7.1 0.38 10.6 1.8 3.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Fes1 PF08609.10 EIM86626.1 - 0.11 13.4 0.4 0.11 13.4 0.4 3.9 5 0 0 5 5 5 0 Nucleotide exchange factor Fes1 PspB PF06667.12 EIM86626.1 - 0.14 12.3 2.9 0.33 11.0 0.5 2.9 2 0 0 2 2 2 0 Phage shock protein B DUF16 PF01519.16 EIM86626.1 - 7.7 7.1 6.4 3.9 8.0 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 CHAT PF12770.7 EIM86627.1 - 1.6e-33 116.4 0.0 2.8e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM86627.1 - 0.95 9.4 16.8 2 8.4 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM86627.1 - 1.1 10.2 6.8 15 6.8 0.0 4.6 4 1 1 6 6 6 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 EIM86628.1 - 1e-40 139.8 0.0 1.3e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EIM86628.1 - 1e-21 77.2 0.0 4.2e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 NAD synthase An_peroxidase PF03098.15 EIM86629.1 - 4.2e-28 98.2 0.0 2.8e-15 55.9 0.0 3.7 2 1 1 3 3 3 2 Animal haem peroxidase p450 PF00067.22 EIM86629.1 - 0.03 13.1 0.0 0.073 11.8 0.0 1.6 1 0 0 1 1 1 0 Cytochrome P450 Pkinase PF00069.25 EIM86630.1 - 5.3e-69 232.5 0.0 8.8e-69 231.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86630.1 - 1.5e-51 175.2 0.0 2.1e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EIM86630.1 - 5.4e-09 35.8 3.8 8.9e-09 35.1 3.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 EIM86630.1 - 0.00049 19.7 2.9 0.001 18.7 2.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Kinase-like PF14531.6 EIM86630.1 - 0.0058 16.0 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 EIM86630.1 - 0.017 14.7 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL C1_2 PF03107.16 EIM86630.1 - 0.029 14.7 2.0 0.057 13.7 2.0 1.5 1 0 0 1 1 1 0 C1 domain Pkinase_fungal PF17667.1 EIM86630.1 - 0.036 12.9 0.0 0.036 12.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 EIM86630.1 - 0.036 13.7 1.2 0.044 13.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 EIM86630.1 - 0.048 12.7 0.1 0.076 12.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PHD PF00628.29 EIM86630.1 - 0.064 13.2 4.8 0.13 12.2 4.8 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EIM86630.1 - 3.6 7.6 8.2 0.86 9.6 4.6 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Macoilin PF09726.9 EIM86630.1 - 6.9 5.1 5.8 9.2 4.7 5.8 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_C14 PF00656.22 EIM86632.1 - 7.5e-26 91.6 0.0 2.7e-25 89.8 0.0 1.8 2 0 0 2 2 2 1 Caspase domain DUF4154 PF13689.6 EIM86632.1 - 0.00016 22.0 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 YfiR/HmsC-like Peptidase_C14 PF00656.22 EIM86633.1 - 4.5e-16 59.5 0.0 6.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain TFIIS_M PF07500.14 EIM86634.1 - 3.6e-19 69.3 0.5 3.6e-19 69.3 0.5 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EIM86634.1 - 2.3e-17 63.3 0.0 4.4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EIM86634.1 - 4.2e-08 33.0 11.1 7.2e-08 32.2 11.1 1.4 1 0 0 1 1 1 1 PHD-finger Mss4 PF04421.13 EIM86634.1 - 0.11 12.7 1.2 0.36 11.0 1.2 1.8 1 0 0 1 1 1 0 Mss4 protein FUSC-like PF12805.7 EIM86634.1 - 4.2 6.4 4.4 6.8 5.7 4.4 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS PKD_channel PF08016.12 EIM86635.1 - 0.0036 16.0 7.3 0.34 9.5 0.2 2.3 1 1 0 2 2 2 2 Polycystin cation channel DUF997 PF06196.12 EIM86635.1 - 0.28 11.2 4.1 0.19 11.7 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF997) Ank_2 PF12796.7 EIM86636.1 - 1.1e-13 51.6 0.0 8.5e-06 26.3 0.0 3.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM86636.1 - 3.3e-11 43.5 0.1 2.2e-09 37.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIM86636.1 - 1.4e-08 34.8 0.5 0.0031 17.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EIM86636.1 - 1.9e-08 34.4 1.0 0.0014 19.0 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EIM86636.1 - 3.7e-08 33.0 0.8 0.035 14.6 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat KilA-N PF04383.13 EIM86636.1 - 0.00098 18.9 0.2 0.017 15.0 0.2 2.3 1 1 0 1 1 1 1 KilA-N domain DUF3562 PF12085.8 EIM86636.1 - 0.035 13.7 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) FPP PF05911.11 EIM86636.1 - 0.036 12.3 0.3 0.049 11.8 0.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Spc29 PF17082.5 EIM86636.1 - 0.086 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Filament PF00038.21 EIM86636.1 - 0.1 12.2 1.6 0.2 11.2 1.6 1.4 1 0 0 1 1 1 0 Intermediate filament protein OmpH PF03938.14 EIM86636.1 - 3.6 7.9 6.2 8.7 6.7 6.2 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PMT PF02366.18 EIM86638.1 - 3.7e-82 275.6 14.5 3.7e-82 275.6 14.5 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EIM86638.1 - 7.6e-63 211.7 7.1 7.6e-63 211.7 7.1 3.0 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EIM86638.1 - 3.6e-18 66.1 1.2 5.5e-18 65.5 1.2 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EIM86638.1 - 1.2e-06 28.9 9.5 1.2e-06 28.9 9.5 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.32 EIM86639.1 - 4.1e-39 131.9 10.5 1.8e-07 31.7 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat PRP4 PF08799.11 EIM86639.1 - 2.9e-13 49.1 1.0 6.9e-13 47.9 1.0 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EIM86639.1 - 1.3e-12 47.8 0.0 0.015 15.6 0.0 5.9 3 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EIM86639.1 - 3.6e-05 23.2 0.1 1.2 8.4 0.0 3.4 2 1 0 3 3 3 3 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 EIM86639.1 - 0.00022 21.2 0.0 0.089 12.7 0.0 3.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EIM86639.1 - 0.00042 19.4 0.0 6.3 5.7 0.0 4.3 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM86639.1 - 0.034 13.5 0.0 3.7 6.8 0.0 3.2 3 1 2 5 5 5 0 WD40-like domain Nup160 PF11715.8 EIM86639.1 - 0.11 11.1 4.2 11 4.5 0.1 4.0 3 1 2 5 5 5 0 Nucleoporin Nup120/160 LEA_6 PF10714.9 EIM86639.1 - 0.16 12.0 2.1 0.35 11.0 2.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 PX PF00787.24 EIM86640.1 - 1.7e-17 63.4 0.0 3.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 PX domain PMC2NT PF08066.12 EIM86640.1 - 0.18 12.5 2.0 12 6.6 0.0 3.0 3 0 0 3 3 3 0 PMC2NT (NUC016) domain U62_UL91 PF17442.2 EIM86640.1 - 0.2 11.6 0.7 4.3 7.4 0.1 3.3 4 0 0 4 4 4 0 Functional domain of U62 and UL91 proteins Glyco_hydro_61 PF03443.14 EIM86641.1 - 8.2e-58 195.7 0.0 9.8e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DWNN PF08783.11 EIM86642.1 - 1.7e-29 101.9 0.7 4.2e-29 100.6 0.7 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EIM86642.1 - 7.7e-11 41.6 6.5 1.6e-10 40.6 6.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EIM86642.1 - 1.8e-06 27.7 1.6 4e-06 26.6 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EIM86642.1 - 0.0031 17.5 0.3 0.0081 16.1 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIM86642.1 - 0.051 13.3 3.7 0.069 12.9 1.6 2.3 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger TFIIA PF03153.13 EIM86642.1 - 0.084 12.9 27.9 0.013 15.5 22.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2407 PF10302.9 EIM86642.1 - 0.24 12.0 1.0 0.64 10.6 1.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Tae4 PF14113.6 EIM86642.1 - 0.29 11.4 2.3 0.69 10.2 2.3 1.6 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 zf-C3HC4_2 PF13923.6 EIM86642.1 - 0.63 9.9 17.6 0.027 14.3 11.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM86642.1 - 1.3 9.0 14.0 0.11 12.4 7.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1510 PF07423.11 EIM86642.1 - 3.6 7.8 7.8 0.14 12.4 0.7 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF1510) zf-C3HC4_4 PF15227.6 EIM86642.1 - 5.4 7.3 9.9 15 5.8 9.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EIM86642.1 - 6.3 7.2 15.7 0.15 12.4 9.1 1.7 2 0 0 2 2 1 0 Ring finger domain ALMT PF11744.8 EIM86642.1 - 8.8 5.0 7.6 18 4.0 7.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Vps5 PF09325.10 EIM86643.1 - 8.4e-61 205.5 5.6 4.6e-59 199.8 5.6 2.1 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EIM86643.1 - 5.2e-23 81.2 0.0 3e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EIM86643.1 - 0.0012 18.3 0.5 0.035 13.6 0.3 2.2 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein TPT PF03151.16 EIM86645.1 - 1.4e-56 192.0 18.1 1.7e-56 191.7 18.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EIM86645.1 - 4.6e-11 43.1 27.6 1.3e-07 31.9 7.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EIM86645.1 - 2.3e-10 40.2 18.0 2.9e-10 39.9 18.0 1.1 1 0 0 1 1 1 1 UAA transporter family HAMP PF00672.25 EIM86646.1 - 5.2e-43 145.2 20.2 7e-07 29.5 0.1 9.1 7 1 0 7 7 7 7 HAMP domain HATPase_c PF02518.26 EIM86646.1 - 2.1e-29 102.3 0.6 2.5e-28 98.8 0.0 3.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM86646.1 - 6.9e-23 80.9 3.0 8.7e-23 80.6 0.5 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EIM86646.1 - 7.7e-17 61.1 1.0 7.7e-17 61.1 1.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EIM86646.1 - 0.013 15.4 0.0 0.051 13.4 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fez1 PF06818.15 EIM86646.1 - 0.053 14.0 3.9 0.32 11.4 1.1 3.4 2 1 0 2 2 2 0 Fez1 DUF4795 PF16043.5 EIM86646.1 - 0.25 10.9 4.6 13 5.3 0.1 3.8 2 1 1 4 4 4 0 Domain of unknown function (DUF4795) SpoIIID PF12116.8 EIM86646.1 - 0.97 9.6 6.5 44 4.2 0.0 5.1 6 0 0 6 6 6 0 Stage III sporulation protein D AIP3 PF03915.13 EIM86646.1 - 4.2 6.3 7.5 0.77 8.8 0.5 2.7 2 2 1 3 3 3 0 Actin interacting protein 3 RTA1 PF04479.13 EIM86649.1 - 1.8e-60 204.1 6.9 2.4e-60 203.7 6.9 1.2 1 0 0 1 1 1 1 RTA1 like protein GAF PF01590.26 EIM86649.1 - 0.2 12.3 0.0 0.34 11.5 0.0 1.3 1 0 0 1 1 1 0 GAF domain CitMHS PF03600.16 EIM86649.1 - 0.59 9.3 7.8 1.4 8.1 7.7 1.7 1 1 0 1 1 1 0 Citrate transporter Fungal_trans PF04082.18 EIM86650.1 - 5.1e-23 81.5 0.4 1.4e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86650.1 - 2e-09 37.4 10.8 3.7e-09 36.6 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EIM86650.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF1604 PF07713.13 EIM86651.1 - 1.4e-38 130.6 0.9 1.4e-38 130.6 0.9 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EIM86651.1 - 2.3e-06 27.4 1.2 6.5e-06 25.9 0.2 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EIM86651.1 - 0.19 11.9 0.1 0.19 11.9 0.1 3.8 4 0 0 4 4 4 0 G-patch domain Mcl1_mid PF12341.8 EIM86652.1 - 1.9e-83 280.3 0.0 8.1e-82 274.9 0.0 2.5 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EIM86652.1 - 1.3e-16 60.6 9.7 1.4e-05 25.8 0.5 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM86652.1 - 3.8e-10 39.9 0.1 0.14 12.4 0.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EIM86652.1 - 0.00012 21.5 0.0 0.29 10.3 0.0 2.6 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller IKI3 PF04762.12 EIM86652.1 - 0.17 9.8 0.1 0.79 7.6 0.1 1.8 1 1 0 1 1 1 0 IKI3 family Rib_recp_KP_reg PF05104.12 EIM86652.1 - 1.7 9.6 6.2 5.9 7.9 3.8 2.4 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region DUF2408 PF10303.9 EIM86653.1 - 1.6e-59 200.3 5.6 3.8e-40 137.6 0.0 5.1 5 0 0 5 5 5 4 Protein of unknown function (DUF2408) CK2S PF15011.6 EIM86653.1 - 0.034 14.0 0.4 0.034 14.0 0.4 3.7 4 1 0 4 4 4 0 Casein Kinase 2 substrate FUSC PF04632.12 EIM86653.1 - 0.049 12.2 0.5 0.068 11.7 0.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Flagellin_N PF00669.20 EIM86653.1 - 0.083 13.0 0.7 56 3.8 0.0 3.8 4 0 0 4 4 4 0 Bacterial flagellin N-terminal helical region ZapA PF05164.13 EIM86653.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.0 4 0 0 4 4 4 0 Cell division protein ZapA Med9 PF07544.13 EIM86653.1 - 5.6 7.1 6.1 2.4 8.3 0.0 3.4 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin_1 PF12718.7 EIM86654.1 - 4e-47 159.9 35.2 4.8e-47 159.7 35.2 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EIM86654.1 - 1e-09 38.1 34.9 0.0002 20.8 6.7 3.0 1 1 2 3 3 3 3 Tropomyosin HHV-5_US34A PF17087.5 EIM86654.1 - 0.0019 18.3 2.5 0.0019 18.3 2.5 2.4 2 1 0 2 2 2 1 Herpesvirus US34A protein family KELK PF15796.5 EIM86654.1 - 0.002 18.6 6.1 0.002 18.6 6.1 3.7 1 1 1 3 3 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Uso1_p115_C PF04871.13 EIM86654.1 - 0.012 16.0 18.4 0.012 16.0 18.4 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DHR10 PF18595.1 EIM86654.1 - 0.012 15.7 36.4 0.25 11.4 15.1 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 EIM86654.1 - 0.019 15.0 36.6 0.19 11.8 10.4 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EIM86654.1 - 0.033 13.6 35.8 0.052 12.9 35.8 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Flagellin_C PF00700.21 EIM86654.1 - 0.048 14.0 3.5 1.2 9.6 0.3 2.5 1 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF3450 PF11932.8 EIM86654.1 - 0.053 12.8 28.4 0.32 10.2 15.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HMMR_N PF15905.5 EIM86654.1 - 0.07 12.6 32.4 0.085 12.3 32.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HGD-D PF06050.13 EIM86654.1 - 0.097 12.4 4.4 0.075 12.8 3.0 1.5 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component HOOK PF05622.12 EIM86654.1 - 0.11 10.6 31.6 0.13 10.4 31.6 1.1 1 0 0 1 1 1 0 HOOK protein HrpB7 PF09486.10 EIM86654.1 - 0.14 12.5 22.5 0.77 10.1 4.5 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 EIM86654.1 - 0.22 11.6 29.4 0.81 9.8 9.3 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EIM86654.1 - 0.26 11.8 42.6 0.14 12.7 26.9 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Alanine_zipper PF11839.8 EIM86654.1 - 0.36 11.2 17.5 0.92 9.9 1.6 3.5 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF724 PF05266.14 EIM86654.1 - 0.45 10.3 29.5 0.63 9.8 10.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TAFH PF07531.14 EIM86654.1 - 0.5 10.5 5.4 0.12 12.5 1.6 2.0 2 1 0 2 2 2 0 NHR1 homology to TAF T3SSipB PF16535.5 EIM86654.1 - 0.56 10.7 23.2 3.2 8.2 15.8 2.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4200 PF13863.6 EIM86654.1 - 0.71 10.3 35.7 1 9.7 10.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4407 PF14362.6 EIM86654.1 - 0.74 9.1 21.3 0.93 8.8 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 EIM86654.1 - 1.1 6.7 29.8 1.6 6.2 29.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sigma70_ner PF04546.13 EIM86654.1 - 1.2 9.0 25.5 1.6 8.5 17.8 2.2 1 1 1 2 2 2 0 Sigma-70, non-essential region FliJ PF02050.16 EIM86654.1 - 1.3 9.2 31.5 2.3 8.5 12.7 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein DUF1664 PF07889.12 EIM86654.1 - 1.5 8.9 17.5 0.11 12.5 6.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EIM86654.1 - 2 8.8 29.4 3 8.3 15.4 2.0 1 1 1 2 2 2 0 Fez1 DUF4201 PF13870.6 EIM86654.1 - 2.3 7.9 31.2 1.7 8.4 24.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 EIM86654.1 - 2.6 8.2 17.7 1.6 8.9 6.8 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 EIM86654.1 - 2.9 8.0 30.4 3.1 7.9 7.3 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding zf-C4H2 PF10146.9 EIM86654.1 - 3.5 7.9 27.1 0.97 9.7 13.2 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein DUF812 PF05667.11 EIM86654.1 - 4.5 6.0 30.2 64 2.2 30.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Med21 PF11221.8 EIM86654.1 - 4.5 7.5 23.2 0.62 10.3 17.3 2.1 1 1 1 2 2 2 0 Subunit 21 of Mediator complex CLZ PF16526.5 EIM86654.1 - 5 7.6 28.5 7.5 7.0 5.8 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF745 PF05335.13 EIM86654.1 - 5.1 6.8 22.7 1 9.1 7.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CTNNBL PF08216.11 EIM86654.1 - 5.2 7.3 14.4 0.27 11.4 7.0 2.4 1 1 2 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Jnk-SapK_ap_N PF09744.9 EIM86654.1 - 6.1 7.1 36.5 1.5 9.0 19.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ERM PF00769.19 EIM86654.1 - 6.2 6.6 36.8 4.4 7.0 21.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 EIM86654.1 - 7.4 4.3 17.0 10 3.9 17.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.12 EIM86654.1 - 7.7 6.5 18.9 6.4 6.8 7.2 2.3 1 1 1 2 2 2 0 Laminin Domain II Csm1_N PF18504.1 EIM86654.1 - 8 6.9 31.5 2.1 8.7 7.7 4.0 1 1 3 4 4 4 0 Csm1 N-terminal domain DUF641 PF04859.12 EIM86654.1 - 8.6 6.7 21.7 6.4 7.1 4.1 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Asp PF00026.23 EIM86655.1 - 1.3e-28 100.3 8.1 6.4e-27 94.8 8.1 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EIM86655.1 - 0.013 16.1 0.7 0.089 13.4 0.0 2.6 2 1 0 2 2 2 0 Aspartyl protease AIF_C PF14721.6 EIM86655.1 - 0.046 14.1 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TAXi_N PF14543.6 EIM86655.1 - 0.055 13.7 5.5 2.9 8.1 0.3 3.0 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EIM86655.1 - 0.1 12.4 0.1 0.77 9.5 0.1 2.2 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal Ank_2 PF12796.7 EIM86656.1 - 8.3e-21 74.4 0.0 5.1e-09 36.6 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIM86656.1 - 9.3e-18 62.5 0.4 0.018 15.5 0.0 6.4 6 0 0 6 6 5 4 Ankyrin repeat Ank_4 PF13637.6 EIM86656.1 - 7.5e-15 55.1 0.0 1.6e-05 25.3 0.0 4.2 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIM86656.1 - 2.7e-14 53.0 0.2 1.4e-06 28.5 0.0 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EIM86656.1 - 1.8e-13 50.2 0.3 0.00075 19.8 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.12 EIM86656.1 - 1.3e-08 34.9 0.0 7.6e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EIM86656.1 - 7.5e-08 32.9 0.1 3.9e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM86656.1 - 6.1e-05 23.3 0.0 0.00021 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EIM86656.1 - 0.00054 19.2 0.2 0.0032 16.7 0.2 2.0 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 EIM86656.1 - 0.00059 19.2 0.0 0.026 13.8 0.0 2.2 1 1 0 2 2 2 1 KAP family P-loop domain AAA_19 PF13245.6 EIM86656.1 - 0.0018 18.6 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 EIM86656.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF1199 PF06712.11 EIM86656.1 - 0.13 12.3 0.4 2.1 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) AAA_33 PF13671.6 EIM86656.1 - 0.15 12.2 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EIM86656.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tim44 PF04280.15 EIM86657.1 - 7.5e-35 120.2 0.5 7.5e-35 120.2 0.5 1.8 2 0 0 2 2 2 1 Tim44-like domain CUTL PF16557.5 EIM86657.1 - 0.06 13.5 0.3 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 CUT1-like DNA-binding domain of SATB DMPK_coil PF08826.10 EIM86657.1 - 0.43 10.7 5.6 0.11 12.7 0.6 2.6 2 1 1 3 3 3 0 DMPK coiled coil domain like Fez1 PF06818.15 EIM86657.1 - 1.3 9.4 10.5 3.9 7.9 10.5 1.7 1 1 0 1 1 1 0 Fez1 T2SSF PF00482.23 EIM86657.1 - 1.7 8.6 5.2 0.96 9.4 2.1 2.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F PIN_8 PF18476.1 EIM86657.1 - 5.6 6.7 7.4 2.1 8.1 2.3 2.1 1 1 0 2 2 2 0 PIN like domain EMP24_GP25L PF01105.24 EIM86658.1 - 4.7e-47 160.3 0.1 5.4e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CAMSAP_CC1 PF17095.5 EIM86658.1 - 0.08 12.8 1.5 0.13 12.1 1.5 1.3 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Brix PF04427.18 EIM86659.1 - 4.9e-24 85.5 0.0 7.6e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain ADH_zinc_N PF00107.26 EIM86660.1 - 3.6e-12 46.4 0.0 6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PRIMA1 PF16101.5 EIM86660.1 - 8.4 6.5 7.3 4.3 7.4 3.7 2.1 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 DUF1295 PF06966.12 EIM86661.1 - 3.9e-34 118.2 5.1 1.4e-32 113.2 5.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Asp PF00026.23 EIM86662.1 - 6.1e-27 94.9 3.6 1.4e-25 90.4 3.6 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EIM86662.1 - 1.5e-05 25.5 0.2 0.09 13.4 0.0 3.8 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EIM86662.1 - 1.8e-05 25.2 0.2 0.053 14.1 0.0 3.5 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EIM86662.1 - 0.004 17.4 3.1 0.5 10.6 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp PF00026.23 EIM86664.1 - 8.7e-24 84.5 2.5 1.3e-21 77.3 2.5 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EIM86664.1 - 0.0095 16.6 0.3 0.82 10.4 0.1 3.2 2 0 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 EIM86664.1 - 0.012 15.9 0.6 2.3 8.4 0.1 2.6 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EIM86664.1 - 0.031 14.8 0.5 4 8.1 0.1 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease ATP-synt_ab PF00006.25 EIM86665.1 - 1.2e-73 247.3 0.0 1.7e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EIM86665.1 - 2.9e-43 147.2 0.2 5e-43 146.4 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EIM86665.1 - 2.1e-17 63.4 0.9 5.8e-17 62.0 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.21 EIM86666.1 - 8.4e-26 90.2 0.1 1e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 EIM86666.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 UvrA interaction domain FF PF01846.19 EIM86667.1 - 1.5e-28 98.7 6.6 3e-09 36.9 0.0 6.2 6 0 0 6 6 6 4 FF domain WW PF00397.26 EIM86667.1 - 1.7e-10 40.8 23.4 3.8e-06 26.9 5.3 3.3 3 0 0 3 3 3 2 WW domain RhoGAP-FF1 PF16512.5 EIM86667.1 - 0.016 15.9 1.9 0.48 11.1 0.3 3.5 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain Voltage_CLC PF00654.20 EIM86669.1 - 2.2e-84 283.7 29.1 2.2e-84 283.7 29.1 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel GMC_oxred_N PF00732.19 EIM86670.1 - 3.3e-45 154.7 0.1 1.3e-26 93.7 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM86670.1 - 6.6e-32 111.0 0.0 1.3e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM86670.1 - 2.1e-05 24.6 1.3 5.8e-05 23.2 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM86670.1 - 4.8e-05 22.6 0.1 0.00018 20.7 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EIM86670.1 - 4.9e-05 23.1 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM86670.1 - 0.00013 21.3 0.1 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM86670.1 - 0.00031 20.1 0.0 0.006 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM86670.1 - 0.0017 17.5 1.1 0.002 17.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIM86670.1 - 0.023 13.4 0.4 0.16 10.7 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 EIM86670.1 - 0.034 14.1 0.1 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 EIM86670.1 - 0.075 12.3 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EIM86670.1 - 0.084 11.7 0.3 0.82 8.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AIDA PF16168.5 EIM86670.1 - 0.24 11.5 2.7 0.3 11.2 0.8 2.2 2 0 0 2 2 1 0 Adhesin of bacterial autotransporter system, probable stalk AbiEii PF08843.11 EIM86674.1 - 0.0012 18.9 0.0 0.004 17.1 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system PRIMA1 PF16101.5 EIM86674.1 - 0.92 9.6 5.3 1.9 8.5 5.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EIM86674.1 - 2.2 7.7 5.7 3.9 6.9 5.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Metallophos PF00149.28 EIM86675.1 - 2.6e-09 37.9 0.0 3.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM86675.1 - 1e-06 29.1 0.0 5.3e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cyto_heme_lyase PF01265.17 EIM86676.1 - 1.1e-70 238.5 4.9 8.7e-69 232.3 4.9 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Osw5 PF17062.5 EIM86678.1 - 8.5 6.5 7.2 0.42 10.7 1.8 1.6 2 0 0 2 2 2 0 Outer spore wall 5 RIFIN PF02009.16 EIM86679.1 - 0.0085 16.0 2.8 0.019 14.9 2.8 1.5 1 0 0 1 1 1 1 Rifin Amnionless PF14828.6 EIM86679.1 - 0.058 12.2 0.7 0.11 11.3 0.7 1.4 1 1 0 1 1 1 0 Amnionless Syndecan PF01034.20 EIM86679.1 - 0.067 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Syndecan domain SKG6 PF08693.10 EIM86679.1 - 0.068 12.6 5.5 0.21 11.0 5.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain stn_TNFRSF12A PF12191.8 EIM86679.1 - 2.2 8.5 6.2 0.49 10.6 0.3 2.7 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Apt1 PF10351.9 EIM86679.1 - 3.1 6.6 15.4 0.25 10.2 10.5 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain FMN_dh PF01070.18 EIM86680.1 - 1.9e-103 346.2 0.0 3.1e-103 345.5 0.0 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EIM86680.1 - 1.3e-05 24.6 0.1 1.8e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EIM86680.1 - 7.7e-05 22.2 0.3 0.00013 21.5 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EIM86680.1 - 0.00012 21.4 0.8 0.044 13.1 0.2 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EIM86680.1 - 0.00013 21.1 0.7 0.00023 20.3 0.5 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 EIM86680.1 - 0.00015 21.1 0.3 0.00034 19.9 0.1 1.6 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EIM86680.1 - 0.0085 15.6 0.5 0.19 11.1 0.1 2.5 1 1 2 3 3 3 1 Histidine biosynthesis protein zf-MYND PF01753.18 EIM86681.1 - 6.7e-11 42.1 9.9 2.4e-10 40.3 9.9 2.0 1 0 0 1 1 1 1 MYND finger Glyco_hydro_18 PF00704.28 EIM86682.1 - 1.3e-60 205.8 0.8 1.6e-60 205.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Oxidored_FMN PF00724.20 EIM86683.1 - 1.7e-83 280.8 0.0 1.9e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HMG_box_2 PF09011.10 EIM86684.1 - 0.00052 20.6 0.3 0.03 14.9 0.0 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 EIM86684.1 - 0.018 15.5 0.8 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box Filament PF00038.21 EIM86687.1 - 0.013 15.1 0.4 0.013 15.1 0.4 1.8 2 0 0 2 2 2 0 Intermediate filament protein DUF3498 PF12004.8 EIM86687.1 - 0.027 13.7 2.7 0.027 13.7 2.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) DUF2968 PF11180.8 EIM86687.1 - 0.096 12.3 1.4 0.14 11.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) G_path_suppress PF15991.5 EIM86688.1 - 9.7 6.2 7.5 19 5.3 7.5 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor Peptidase_M20 PF01546.28 EIM86689.1 - 1.3e-29 103.4 0.0 3.1e-29 102.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM86689.1 - 2.3e-09 37.1 0.0 5.5e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM86689.1 - 0.00077 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIM86690.1 - 9.8e-25 87.5 0.0 2.2e-24 86.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM86690.1 - 2.4e-10 40.3 0.0 8.6e-10 38.5 0.0 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM86690.1 - 0.0086 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 zf-C2H2 PF00096.26 EIM86691.1 - 6e-27 92.6 50.2 2.1e-06 27.9 0.1 8.5 8 1 0 8 8 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM86691.1 - 2.3e-22 78.3 43.9 1.8e-06 28.1 0.3 7.9 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM86691.1 - 1.3e-16 59.9 47.1 0.00011 22.7 1.6 8.6 8 1 1 9 9 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM86691.1 - 1.1e-06 28.8 8.9 0.0028 17.9 0.5 4.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EIM86691.1 - 9.1e-05 22.1 1.8 9.1e-05 22.1 1.8 7.4 8 0 0 8 8 7 3 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 EIM86691.1 - 9.2e-05 22.2 5.9 0.9 9.5 0.0 4.9 5 0 0 5 5 5 2 zinc-finger of a C2HC-type FOXP-CC PF16159.5 EIM86691.1 - 0.00013 22.6 39.7 0.05 14.2 0.3 8.0 5 2 2 7 7 7 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EIM86691.1 - 0.00028 21.1 18.7 0.042 14.2 3.2 4.7 2 1 2 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EIM86691.1 - 0.00057 19.8 33.6 0.055 13.5 1.6 7.2 7 1 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EIM86691.1 - 0.00086 19.6 26.5 0.38 11.1 5.4 5.3 3 2 2 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EIM86691.1 - 0.065 13.7 0.5 0.065 13.7 0.5 4.0 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EIM86691.1 - 0.078 13.4 15.6 0.4 11.1 0.5 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type CCAP PF11105.8 EIM86691.1 - 0.14 12.1 5.1 3.4 7.6 1.3 2.3 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-C2H2_9 PF16293.5 EIM86691.1 - 0.15 11.9 7.4 4.7 7.1 0.1 4.8 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 EIM86691.1 - 0.18 11.6 22.6 0.52 10.1 0.5 5.9 6 0 0 6 6 6 0 zinc-finger C2H2-type Thaumatin PF00314.17 EIM86692.1 - 9.7e-09 35.2 13.9 1.3e-08 34.8 13.9 1.2 1 0 0 1 1 1 1 Thaumatin family DNA_pol_E_B PF04042.16 EIM86693.1 - 1e-42 145.9 0.1 1.7e-42 145.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EIM86693.1 - 0.0075 16.4 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain Forkhead PF00250.18 EIM86694.1 - 7.9e-25 86.9 0.1 1.7e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain BTB PF00651.31 EIM86695.1 - 1e-09 38.6 0.0 0.001 19.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DZR PF12773.7 EIM86695.1 - 0.012 15.7 2.8 6.3 6.9 0.0 3.9 4 0 0 4 4 4 0 Double zinc ribbon TniQ PF06527.11 EIM86695.1 - 2.3 9.0 5.1 38 5.0 0.0 4.0 3 1 1 4 4 4 0 TniQ Med27 PF11571.8 EIM86695.1 - 4.4 7.7 4.8 12 6.3 0.0 3.7 4 1 1 5 5 5 0 Mediator complex subunit 27 Adaptin_N PF01602.20 EIM86696.1 - 3.2e-142 474.8 8.9 3.7e-142 474.6 8.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EIM86696.1 - 8.4e-22 77.6 0.3 2.1e-21 76.3 0.3 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EIM86696.1 - 1.7e-08 34.7 10.0 8.9e-07 29.1 0.3 3.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIM86696.1 - 0.0035 17.7 3.5 1.6 9.2 0.2 3.9 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EIM86696.1 - 0.0044 17.2 0.7 30 5.3 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat NPCBM_assoc PF10633.9 EIM86696.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Peptidase_M73 PF12389.8 EIM86696.1 - 0.057 13.3 0.2 0.095 12.5 0.2 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase UDPGP PF01704.18 EIM86696.1 - 0.28 9.8 1.3 0.44 9.1 0.2 1.7 2 0 0 2 2 2 0 UTP--glucose-1-phosphate uridylyltransferase SF3b1 PF08920.10 EIM86697.1 - 2.3e-25 89.4 1.0 2.3e-25 89.4 1.0 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EIM86697.1 - 4.2e-10 39.9 4.5 0.013 16.0 0.0 7.9 9 1 1 10 10 10 2 HEAT-like repeat HEAT_2 PF13646.6 EIM86697.1 - 1.5e-08 34.9 14.2 0.012 16.0 0.1 8.0 5 2 4 9 9 8 2 HEAT repeats HEAT PF02985.22 EIM86697.1 - 4.1e-08 32.8 11.8 0.06 13.6 0.1 9.8 12 0 0 12 12 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EIM86697.1 - 1.6e-06 28.6 1.3 1.2 9.8 0.0 5.2 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EIM86697.1 - 7e-06 26.2 8.4 0.53 10.3 0.0 6.6 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EIM86697.1 - 2.7e-05 22.9 1.7 0.025 13.2 0.1 3.3 2 1 0 3 3 3 1 Adaptin N terminal region NUC173 PF08161.12 EIM86697.1 - 3.9e-05 23.4 1.0 1.9 8.1 0.0 5.0 4 1 1 5 5 5 2 NUC173 domain UME PF08064.13 EIM86697.1 - 0.00021 21.2 0.2 0.31 11.0 0.0 4.5 4 2 2 6 6 6 1 UME (NUC010) domain CLASP_N PF12348.8 EIM86697.1 - 0.00057 19.5 1.7 1.2 8.7 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal DUF3110 PF11360.8 EIM86697.1 - 0.019 15.1 0.1 0.059 13.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dopey_N PF04118.14 EIM86697.1 - 0.087 11.9 2.2 4.4 6.3 0.0 3.6 4 0 0 4 4 4 0 Dopey, N-terminal Helicase_C PF00271.31 EIM86698.1 - 9.5e-23 80.7 0.6 6.1e-22 78.1 0.6 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Alpha_kinase PF02816.18 EIM86701.1 - 9.8e-19 68.2 0.0 1.7e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family DNA_ligase_A_M PF01068.21 EIM86702.1 - 2.7e-53 180.7 0.0 4.7e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIM86702.1 - 8.8e-41 140.1 0.0 2.1e-40 138.8 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EIM86702.1 - 4.5e-24 84.7 0.2 1.1e-11 44.9 0.0 3.1 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 EIM86702.1 - 2.2e-15 57.1 0.0 8e-15 55.2 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EIM86702.1 - 2.2e-13 50.8 0.3 6.8e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 RNA ligase BRCT PF00533.26 EIM86702.1 - 2.9e-07 30.8 0.1 0.0081 16.5 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EIM86702.1 - 1.7e-06 28.2 0.0 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EIM86702.1 - 8.2e-05 22.5 0.0 0.13 12.2 0.0 2.8 2 0 0 2 2 2 2 twin BRCT domain DUF4073 PF13285.6 EIM86702.1 - 0.013 15.2 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) RTT107_BRCT_5 PF16770.5 EIM86702.1 - 0.022 14.6 0.0 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain RhoGAP PF00620.27 EIM86703.1 - 3.5e-36 124.3 0.0 6.3e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EIM86703.1 - 7.1e-27 93.4 38.1 2.1e-10 40.6 0.5 4.6 4 0 0 4 4 4 4 LIM domain Pkinase_fungal PF17667.1 EIM86704.1 - 9.4e-67 225.6 0.0 4.8e-66 223.2 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EIM86704.1 - 4.5e-05 23.5 2.8 0.0001 22.3 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM86704.1 - 5.9e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86704.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ribosomal_S19 PF00203.21 EIM86705.1 - 9.8e-34 115.1 0.3 1.4e-33 114.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 EIM86705.1 - 0.013 15.6 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Ribosomal_60s PF00428.19 EIM86706.1 - 4.6e-28 97.6 14.1 5.3e-28 97.4 14.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 EIM86706.1 - 0.48 8.8 1.5 0.54 8.7 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Fungal_trans PF04082.18 EIM86707.1 - 4e-10 39.2 0.3 7.6e-10 38.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86707.1 - 6.9e-10 38.9 10.0 1.2e-09 38.1 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_fungal PF17667.1 EIM86708.1 - 1.4e-58 198.6 0.0 1.8e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM86708.1 - 0.00061 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM86708.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Corona_5a PF06336.11 EIM86708.1 - 0.035 14.1 0.3 0.081 12.9 0.3 1.6 1 0 0 1 1 1 0 Coronavirus 5a protein Pkinase_Tyr PF07714.17 EIM86708.1 - 0.043 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UspB PF10625.9 EIM86708.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein B (UspB) ParA PF10609.9 EIM86710.1 - 1.2e-96 322.9 0.0 1.4e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EIM86710.1 - 1.3e-08 35.0 0.0 5.4e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EIM86710.1 - 0.00017 20.9 1.6 0.0029 16.8 0.4 2.5 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EIM86710.1 - 0.00035 20.5 0.1 0.0028 17.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EIM86710.1 - 0.00043 19.8 0.0 0.82 9.1 0.0 2.5 2 1 1 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EIM86710.1 - 0.001 18.6 0.0 0.0062 16.0 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EIM86710.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EIM86710.1 - 0.019 14.9 0.1 0.043 13.7 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase AAA_26 PF13500.6 EIM86710.1 - 0.022 14.6 0.0 0.083 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIM86710.1 - 0.052 12.7 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.11 EIM86710.1 - 0.26 11.0 0.1 0.41 10.3 0.1 1.2 1 0 0 1 1 1 0 Virulence-associated protein E DnaJ PF00226.31 EIM86711.1 - 2.8e-12 46.6 3.8 3.8e-12 46.2 0.3 2.8 2 1 0 2 2 2 1 DnaJ domain DUF4047 PF13256.6 EIM86711.1 - 0.2 11.8 7.7 0.42 10.8 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Pkinase PF00069.25 EIM86712.1 - 7.2e-68 228.8 0.0 9.8e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86712.1 - 2.7e-35 121.9 0.0 3.9e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM86712.1 - 0.00058 18.9 0.1 0.00089 18.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIM86712.1 - 0.0082 16.1 0.3 0.12 12.2 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM86712.1 - 0.058 12.7 0.1 0.14 11.4 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EIM86712.1 - 0.065 12.9 0.1 1.9 8.1 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EIM86712.1 - 0.097 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EIM86712.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Symplekin_C PF12295.8 EIM86713.1 - 2.5e-63 213.6 0.6 6.2e-63 212.3 0.6 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EIM86713.1 - 8.8e-49 166.2 0.0 4.7e-48 163.8 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3453) HEAT PF02985.22 EIM86713.1 - 0.029 14.6 3.0 7.4 7.1 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat V-ATPase_G PF03179.15 EIM86714.1 - 4.3e-35 120.4 13.9 5.1e-35 120.2 13.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF4456 PF14644.6 EIM86714.1 - 0.018 14.7 5.2 0.023 14.4 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Muted PF14942.6 EIM86714.1 - 0.16 12.3 7.6 0.25 11.7 7.6 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein RRF PF01765.19 EIM86714.1 - 0.24 11.3 7.6 0.36 10.8 7.6 1.3 1 0 0 1 1 1 0 Ribosome recycling factor ATP-synt_B PF00430.18 EIM86714.1 - 0.34 11.0 17.9 0.61 10.2 17.2 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4407 PF14362.6 EIM86714.1 - 0.87 8.9 7.1 1 8.6 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 EIM86714.1 - 1 9.6 9.3 3 8.1 8.7 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V-ATPase_G_2 PF16999.5 EIM86714.1 - 2.4 8.6 15.8 34 4.9 0.2 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit PGBA_C PF15437.6 EIM86714.1 - 2.9 8.3 11.9 0.42 11.0 7.2 1.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal TPR_12 PF13424.6 EIM86715.1 - 2.2e-28 98.4 12.9 1e-09 38.6 0.6 4.9 3 2 3 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EIM86715.1 - 7.1e-28 95.7 8.0 1.1e-09 37.8 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EIM86715.1 - 2.9e-08 33.3 7.6 0.04 14.1 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM86715.1 - 5.9e-08 33.1 2.7 0.04 14.4 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM86715.1 - 6e-08 32.2 9.7 0.096 12.9 0.5 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 EIM86715.1 - 1.8e-07 31.1 4.7 0.33 11.7 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM86715.1 - 1.3e-05 25.8 3.3 8.8 7.1 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86715.1 - 0.00027 20.6 3.9 2.6 8.0 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EIM86715.1 - 0.0024 18.2 7.1 3.3 8.1 0.3 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM86715.1 - 0.0051 17.4 5.8 2.5 8.9 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM86715.1 - 0.011 15.8 0.3 6.7 6.9 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EIM86715.1 - 0.045 14.0 0.7 22 5.4 0.0 3.2 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EIM86715.1 - 0.061 13.6 0.7 17 5.9 0.1 3.4 3 0 0 3 3 3 0 PPR repeat TPR_14 PF13428.6 EIM86715.1 - 0.12 13.2 7.2 2 9.4 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM86715.1 - 0.19 11.9 3.5 0.36 11.0 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM86717.1 - 1.8e-23 82.3 0.5 3e-23 81.6 0.5 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EIM86717.1 - 4.8e-15 54.9 0.0 7.4e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EIM86717.1 - 0.00057 19.8 0.4 0.00057 19.8 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM86717.1 - 0.0022 18.4 0.4 0.0055 17.2 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM86717.1 - 0.0083 15.9 0.5 0.024 14.5 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIM86717.1 - 0.017 15.8 0.1 0.071 13.8 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM86717.1 - 0.039 14.2 0.6 0.1 12.9 0.4 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIM86717.1 - 0.075 13.1 0.1 0.23 11.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat NmrA PF05368.13 EIM86718.1 - 1.5e-25 90.1 0.0 1.9e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM86718.1 - 6.3e-08 32.7 0.0 1.5e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EIM86718.1 - 0.024 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EIM86718.1 - 0.036 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EIM86718.1 - 0.04 14.2 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SAM_PNT PF02198.16 EIM86718.1 - 0.045 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain NAD_binding_3 PF03447.16 EIM86718.1 - 0.089 13.5 0.0 0.27 11.9 0.0 1.9 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain LpxI_N PF17930.1 EIM86718.1 - 0.16 11.9 0.0 6.3 6.7 0.0 2.8 3 0 0 3 3 3 0 LpxI N-terminal domain NmrA PF05368.13 EIM86719.1 - 7.9e-08 32.1 0.2 0.0069 16.0 0.0 2.4 2 1 1 3 3 3 2 NmrA-like family NAD_binding_10 PF13460.6 EIM86719.1 - 0.003 17.5 0.0 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 EIM86719.1 - 0.038 14.6 0.3 0.61 10.7 0.1 2.7 1 1 2 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DRMBL PF07522.14 EIM86720.1 - 3.5e-28 98.0 0.0 7.4e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EIM86720.1 - 1.1e-07 31.6 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM86720.1 - 0.043 13.8 0.7 0.1 12.6 0.6 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily ANAPC4_WD40 PF12894.7 EIM86721.1 - 1.5e-08 34.8 0.4 0.23 11.8 0.0 4.7 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM86721.1 - 5.6e-08 33.3 11.8 0.019 15.8 0.3 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat DnaJ PF00226.31 EIM86722.1 - 5.9e-23 80.8 3.4 1e-22 80.0 3.4 1.4 1 0 0 1 1 1 1 DnaJ domain hDGE_amylase PF14701.6 EIM86724.1 - 1.2e-152 509.1 0.0 1.5e-152 508.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EIM86724.1 - 5.9e-119 397.4 0.0 7.9e-119 397.0 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EIM86724.1 - 3.9e-80 269.2 0.0 5.4e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EIM86724.1 - 1.4e-21 76.4 0.0 3.2e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme PAT1 PF09770.9 EIM86725.1 - 2.2e-105 353.8 64.7 2.3e-102 343.8 64.7 3.3 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 NmrA PF05368.13 EIM86726.1 - 1.3e-28 100.2 0.0 1.5e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM86726.1 - 4e-12 46.4 0.0 1.1e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM86726.1 - 1.7e-08 34.7 0.1 3.4e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EIM86726.1 - 7.9e-05 21.8 0.1 0.00011 21.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EIM86726.1 - 0.00043 20.4 0.1 0.00078 19.5 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EIM86726.1 - 0.0015 18.1 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 EIM86726.1 - 0.0036 17.0 0.1 0.0055 16.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.16 EIM86726.1 - 0.0062 17.2 0.1 1.4 9.6 0.0 2.4 1 1 1 2 2 2 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 EIM86726.1 - 0.0085 16.4 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 EIM86726.1 - 0.025 13.9 0.2 0.046 13.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EIM86726.1 - 0.04 13.4 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus KR PF08659.10 EIM86726.1 - 0.06 13.3 0.4 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.17 EIM86726.1 - 0.073 13.7 0.4 0.16 12.6 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SBP_bac_11 PF13531.6 EIM86726.1 - 0.073 12.8 0.5 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF1697 PF08002.11 EIM86726.1 - 0.095 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) ThiF PF00899.21 EIM86726.1 - 0.1 12.0 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 ThiF family Mito_carr PF00153.27 EIM86728.1 - 1.8e-66 220.1 3.7 6e-22 77.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein KduI PF04962.12 EIM86728.1 - 0.046 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 KduI/IolB family Pribosyltran PF00156.27 EIM86729.1 - 0.078 12.5 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase domain RNA_pol_Rpc4 PF05132.14 EIM86730.1 - 3.3e-34 118.5 3.9 1e-33 116.9 0.3 2.5 2 0 0 2 2 2 1 RNA polymerase III RPC4 Fungal_trans PF04082.18 EIM86731.1 - 3e-23 82.2 1.1 5.6e-23 81.3 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM86731.1 - 3.9e-06 26.9 10.5 9e-06 25.7 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EIM86732.1 - 0.0034 17.3 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like GRIM-19 PF06212.12 EIM86732.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 GRIM-19 protein TFIID_30kDa PF03540.13 EIM86733.1 - 9.9e-27 92.7 0.2 1.4e-26 92.1 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 EIM86733.1 - 0.00053 19.9 0.0 0.074 13.1 0.0 2.2 2 0 0 2 2 2 2 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EIM86733.1 - 0.08 13.2 0.1 7.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GFO_IDH_MocA PF01408.22 EIM86734.1 - 6.6e-18 65.7 0.1 9.9e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_3 PF07859.13 EIM86735.1 - 1e-45 156.2 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM86735.1 - 3.5e-08 32.8 0.0 7.8e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EIM86735.1 - 0.04 12.8 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase SAGA-Tad1 PF12767.7 EIM86736.1 - 1.3e-23 83.9 0.0 1.9e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 EIM86736.1 - 0.0078 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family zf-CCCH_4 PF18044.1 EIM86737.1 - 5.6e-07 29.2 30.7 0.001 18.8 4.4 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 EIM86737.1 - 1.8e-05 25.4 15.9 0.00033 21.3 0.8 3.4 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 EIM86737.1 - 2.6e-05 24.0 4.5 2.6e-05 24.0 4.5 4.1 4 1 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIM86737.1 - 3.5e-05 23.7 9.1 3.5e-05 23.7 9.1 4.3 4 1 0 4 4 4 2 Zinc finger domain zf-C3HC4_3 PF13920.6 EIM86737.1 - 0.0012 18.6 3.2 0.11 12.3 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM86737.1 - 0.0016 18.4 4.4 0.0091 15.9 4.4 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM86737.1 - 0.011 15.6 6.0 0.017 15.0 1.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 EIM86737.1 - 0.029 14.8 0.5 0.029 14.8 0.5 4.2 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-RING_UBOX PF13445.6 EIM86737.1 - 0.031 14.3 2.3 0.12 12.4 2.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EIM86737.1 - 0.068 13.5 0.7 0.068 13.5 0.7 3.3 3 0 0 3 3 3 0 Ring finger domain Gemini_coat PF00844.18 EIM86740.1 - 0.052 13.0 0.1 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family HHH_2 PF12826.7 EIM86742.1 - 0.13 12.3 0.1 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Radical_SAM_N PF08497.10 EIM86743.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal NAD-GH PF10712.9 EIM86743.1 - 0.12 10.8 0.1 0.14 10.6 0.1 1.0 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase SKN1 PF03935.15 EIM86744.1 - 1.1e-203 677.2 6.0 1.3e-203 677.0 6.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FAD_binding_3 PF01494.19 EIM86745.1 - 3.2e-25 89.1 0.0 6e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM86745.1 - 7.4e-06 26.1 1.9 1.8e-05 24.9 1.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EIM86745.1 - 8.3e-05 21.6 1.3 0.013 14.4 0.7 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 EIM86745.1 - 0.00017 20.4 1.0 0.00032 19.5 1.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM86745.1 - 0.00072 18.9 0.4 0.0029 16.9 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM86745.1 - 0.016 14.5 2.3 0.018 14.3 0.8 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EIM86745.1 - 0.021 15.4 1.5 0.042 14.4 1.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM86745.1 - 0.04 13.0 0.9 0.058 12.5 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 EIM86745.1 - 0.052 12.6 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 EIM86745.1 - 0.092 12.0 2.3 0.15 11.3 2.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM86745.1 - 0.094 12.7 3.9 10 6.1 1.5 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 EIM86745.1 - 0.11 12.1 6.0 0.24 11.0 6.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM86745.1 - 0.19 10.8 5.0 0.29 10.1 5.0 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EIM86745.1 - 4.2 6.6 5.5 64 2.7 3.2 3.0 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Histone_H2A_C PF16211.5 EIM86746.1 - 1.9e-17 62.7 1.0 3.9e-17 61.7 1.0 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EIM86746.1 - 3.8e-17 62.9 0.0 4.4e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIM86746.1 - 5.2e-06 26.7 0.0 7.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hydrolase_like PF13242.6 EIM86747.1 - 6e-07 29.4 0.1 1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EIM86747.1 - 0.01 16.1 0.1 0.088 13.1 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Carb_kinase PF01256.17 EIM86748.1 - 1.8e-51 175.0 0.0 3.1e-51 174.2 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EIM86748.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Hydrolase_like PF13242.6 EIM86749.1 - 1e-06 28.7 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EIM86749.1 - 1.6e-06 28.4 0.0 2e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM86749.1 - 2.6e-06 27.9 0.0 5e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase G_glu_transpept PF01019.21 EIM86750.1 - 2.2e-154 515.0 2.4 2.6e-154 514.8 2.4 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase BTB PF00651.31 EIM86751.1 - 1.2e-06 28.7 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ribonuc_P_40 PF08584.11 EIM86752.1 - 8.9e-16 58.0 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Lipase_3 PF01764.25 EIM86754.1 - 7.2e-33 113.4 0.0 9.6e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 EIM86754.1 - 0.0026 17.7 0.4 0.0052 16.8 0.4 1.4 1 1 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.8 EIM86754.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 EIM86754.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 EIM86754.1 - 0.072 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein OTT_1508_deam PF14441.6 EIM86755.1 - 1.6e-10 40.8 3.7 2.2e-10 40.4 2.6 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase IL4 PF00727.18 EIM86755.1 - 0.12 12.6 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 Interleukin 4 p450 PF00067.22 EIM86756.1 - 2e-37 129.1 0.0 1.2e-19 70.4 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EIM86757.1 - 0.0031 16.3 0.0 0.0034 16.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribonucleas_3_3 PF14622.6 EIM86758.1 - 2e-07 31.2 0.0 3.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIM86758.1 - 9.9e-07 29.3 0.0 4.2e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 EIM86758.1 - 5.8e-06 26.9 0.0 1.2e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif RhoGAP PF00620.27 EIM86759.1 - 1.2e-09 38.2 0.0 2.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EIM86759.1 - 3.2e-07 30.5 0.0 8.2e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 EIM86759.1 - 1.1e-06 28.6 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.16 EIM86762.1 - 5.2e-35 121.0 28.6 7e-34 117.3 31.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PACT_coil_coil PF10495.9 EIM86763.1 - 1.9e-13 50.7 1.4 1.9e-13 50.7 1.4 4.4 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 EIM86763.1 - 0.002 18.1 18.7 0.002 18.1 18.7 10.8 3 2 5 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EIM86763.1 - 0.0034 16.9 9.6 0.0034 16.9 9.6 7.3 3 2 3 7 7 7 1 Hyaluronan mediated motility receptor N-terminal ZapB PF06005.12 EIM86763.1 - 0.0059 17.0 7.0 0.0059 17.0 7.0 15.1 8 4 4 12 12 12 2 Cell division protein ZapB KASH_CCD PF14662.6 EIM86763.1 - 0.13 12.1 0.0 0.13 12.1 0.0 9.8 4 2 5 9 9 9 0 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 EIM86763.1 - 0.17 10.4 0.0 0.17 10.4 0.0 5.7 3 2 2 5 5 5 0 Macoilin family CDP-OH_P_transf PF01066.21 EIM86764.1 - 1.3e-13 51.5 1.8 1.3e-13 51.5 1.8 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WLM PF08325.10 EIM86765.1 - 2.7e-37 128.7 0.3 9.7e-37 126.9 0.0 1.9 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 EIM86765.1 - 4.5e-10 39.1 0.0 8.9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 EIM86765.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Zincin_1 PF06262.11 EIM86765.1 - 0.022 14.9 0.0 0.09 12.9 0.0 2.0 2 0 0 2 2 2 0 Zincin-like metallopeptidase Ubiquitin_2 PF14560.6 EIM86765.1 - 0.027 14.9 0.0 0.07 13.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain DUF45 PF01863.17 EIM86765.1 - 0.034 14.2 0.3 0.15 12.1 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function DUF45 Oxidored_FMN PF00724.20 EIM86767.1 - 1.9e-09 37.3 0.0 8e-09 35.2 0.0 1.8 1 1 1 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family SUZ PF12752.7 EIM86768.1 - 0.0097 16.6 1.5 0.016 16.0 1.5 1.5 1 1 0 1 1 1 1 SUZ domain Aa_trans PF01490.18 EIM86769.1 - 6.2e-82 275.5 16.9 7.8e-82 275.2 16.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EIM86769.1 - 0.00021 20.5 18.3 0.00028 20.1 15.4 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2909 PF11137.8 EIM86769.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) Ycf9 PF01737.17 EIM86769.1 - 2.3 8.2 7.5 1.1 9.2 2.5 2.5 2 0 0 2 2 2 0 YCF9 DUF202 PF02656.15 EIM86771.1 - 0.00013 22.3 0.6 0.00044 20.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SLC35F PF06027.12 EIM86773.1 - 1.1e-95 320.7 19.2 1.3e-95 320.4 19.2 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EIM86773.1 - 2.5e-07 30.0 0.3 5e-07 29.0 0.3 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EIM86773.1 - 0.11 12.6 29.2 0.12 12.5 7.5 3.1 2 1 1 3 3 3 0 EamA-like transporter family Deltameth_res PF16020.5 EIM86773.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.7 4 0 0 4 4 4 0 Deltamethrin resistance Wzy_C PF04932.15 EIM86773.1 - 2.1 7.9 9.7 1.6 8.3 1.4 3.0 1 1 1 2 2 2 0 O-Antigen ligase OHCU_decarbox PF09349.10 EIM86774.1 - 3.3e-37 128.3 0.0 4.3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase LcrG PF07216.12 EIM86774.1 - 0.0054 16.6 0.2 0.017 15.0 0.0 1.9 3 0 0 3 3 3 1 LcrG protein FAD_binding_3 PF01494.19 EIM86775.1 - 3.9e-23 82.3 0.0 8.9e-23 81.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM86775.1 - 7.8e-07 29.2 1.8 1.8e-06 28.1 1.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EIM86775.1 - 0.00015 20.8 3.4 0.00082 18.3 0.9 2.3 1 1 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 EIM86775.1 - 0.00042 19.1 1.8 0.00061 18.6 0.6 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM86775.1 - 0.00058 19.2 3.0 0.0023 17.2 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EIM86775.1 - 0.00066 18.8 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.24 EIM86775.1 - 0.0057 16.0 0.2 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EIM86775.1 - 0.01 16.4 2.6 0.027 15.0 1.6 2.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM86775.1 - 0.012 15.2 4.7 0.019 14.6 3.6 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EIM86775.1 - 0.014 14.6 2.7 0.016 14.4 0.5 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EIM86775.1 - 0.017 14.4 4.3 0.023 13.9 1.7 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM86775.1 - 0.019 15.0 0.9 4.7 7.2 0.4 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 EIM86775.1 - 0.046 12.8 0.9 0.072 12.2 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EIM86775.1 - 0.17 10.9 5.2 0.3 10.1 5.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.25 EIM86776.1 - 4.4e-06 26.3 0.0 7.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM86776.1 - 0.0013 18.7 0.1 0.87 9.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EIM86776.1 - 0.0025 17.5 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EIM86776.1 - 0.0025 16.7 0.0 0.0065 15.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase WaaY PF06176.11 EIM86776.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Glyco_hydro_35 PF01301.19 EIM86777.1 - 6.2e-76 256.0 1.1 8.9e-76 255.5 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EIM86777.1 - 1.4e-47 160.9 3.0 2.3e-26 92.6 0.0 3.2 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EIM86777.1 - 1.6e-45 155.1 12.2 3.3e-45 154.1 12.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EIM86777.1 - 1.6e-25 88.5 0.2 6.3e-25 86.5 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 EIM86777.1 - 0.0014 18.2 0.7 0.007 15.8 0.8 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Oxidored_FMN PF00724.20 EIM86778.1 - 9.5e-32 110.6 0.0 1.4e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1752 PF08550.10 EIM86779.1 - 6e-10 38.8 9.4 1.2e-09 37.8 9.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MTHFR PF02219.17 EIM86780.1 - 1.8e-43 148.9 0.0 2.6e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Oxidored_FMN PF00724.20 EIM86782.1 - 3.7e-36 125.1 0.0 4.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.21 EIM86783.1 - 1.5e-69 234.5 0.0 1.7e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 EIM86783.1 - 0.28 11.2 1.3 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PseudoU_synth_1 PF01416.20 EIM86784.1 - 7e-12 45.8 0.0 1.5e-09 38.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase SCA7 PF08313.12 EIM86787.1 - 7.2e-28 96.3 0.2 7.2e-28 96.3 0.2 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain TMV_coat PF00721.21 EIM86787.1 - 0.11 12.4 2.5 0.21 11.4 2.5 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) zf_UBZ PF18439.1 EIM86787.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger FAD_binding_3 PF01494.19 EIM86788.1 - 1.7e-18 67.0 0.1 8.1e-17 61.5 0.1 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM86788.1 - 1.5e-07 31.5 0.5 4e-07 30.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM86788.1 - 1.1e-05 24.8 0.8 2.1e-05 23.8 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM86788.1 - 0.00033 20.3 2.4 0.00096 18.8 2.4 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM86788.1 - 0.011 15.0 1.0 0.049 12.8 0.5 2.2 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM86788.1 - 0.017 14.3 1.2 0.025 13.8 0.4 1.6 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 EIM86788.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM86788.1 - 0.028 13.1 0.4 0.1 11.3 0.7 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EIM86788.1 - 0.11 11.5 1.3 0.28 10.2 0.7 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EIM86788.1 - 0.18 12.4 0.4 0.51 10.9 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EIM86789.1 - 3.7e-71 239.6 0.0 4.3e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86789.1 - 7.7e-31 107.3 0.0 1.6e-30 106.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM86789.1 - 0.0021 17.5 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIM86789.1 - 0.021 14.7 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM86789.1 - 0.093 11.7 0.0 0.99 8.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain zf-RanBP PF00641.18 EIM86792.1 - 5.8e-10 38.3 39.5 5.3e-07 28.8 4.6 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others NADH-u_ox-rdase PF10785.9 EIM86793.1 - 1.8e-30 105.4 0.2 2.6e-30 104.9 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EIM86793.1 - 1.7e-11 44.0 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Pantoate_ligase PF02569.15 EIM86794.1 - 6.4e-89 297.7 0.0 7.4e-89 297.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PAP2 PF01569.21 EIM86795.1 - 1.8e-13 50.4 9.0 1.8e-13 50.4 9.0 1.6 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EIM86795.1 - 0.0013 18.9 1.0 0.35 11.0 0.0 2.8 2 1 1 3 3 3 2 Divergent PAP2 family UbiA PF01040.18 EIM86795.1 - 7.2 5.8 19.2 0.64 9.3 11.2 2.4 1 1 2 3 3 3 0 UbiA prenyltransferase family BCS1_N PF08740.11 EIM86796.1 - 5.3e-44 150.4 1.9 8.9e-44 149.7 1.9 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EIM86796.1 - 1.2e-16 61.3 0.0 8.1e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM86796.1 - 0.00053 20.4 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EIM86796.1 - 0.0083 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EIM86796.1 - 0.021 14.0 0.0 0.046 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EIM86796.1 - 0.022 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EIM86796.1 - 0.033 14.6 0.0 0.096 13.1 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 EIM86796.1 - 0.078 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EIM86796.1 - 0.098 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Polysacc_synt PF01943.17 EIM86796.1 - 0.1 11.9 0.5 0.16 11.4 0.5 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_22 PF13401.6 EIM86796.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIM86796.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EIM86796.1 - 0.14 12.7 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EIM86796.1 - 0.19 10.7 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ATPase_2 PF01637.18 EIM86796.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MSA-2c PF12238.8 EIM86796.1 - 0.92 9.5 4.6 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c VPS9 PF02204.18 EIM86798.1 - 4.3e-31 107.2 0.1 7.4e-31 106.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EIM86798.1 - 4.9e-16 58.8 0.1 1.3e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EIM86798.1 - 3.4e-05 23.4 0.0 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 CUE domain NrsF PF06532.11 EIM86800.1 - 0.00076 19.2 0.8 0.00076 19.2 0.8 1.7 2 0 0 2 2 2 1 Negative regulator of sigma F DDDD PF10161.9 EIM86800.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.9 4 0 0 4 4 4 0 Putative mitochondrial precursor protein DUF4131 PF13567.6 EIM86800.1 - 3.2 7.4 7.5 0.18 11.4 0.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HMG_CoA_synt_C PF08540.10 EIM86801.1 - 2.4e-92 309.6 0.2 3.1e-92 309.2 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EIM86801.1 - 1.1e-82 276.1 0.2 1.8e-82 275.4 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BTB PF00651.31 EIM86802.1 - 6.7e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PGM_PMM_I PF02878.16 EIM86803.1 - 3.8e-36 123.8 0.2 6.1e-36 123.2 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EIM86803.1 - 1.2e-26 93.2 0.0 4.5e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EIM86803.1 - 1.3e-14 54.6 0.0 3.5e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EIM86803.1 - 3.1e-05 24.1 0.0 8.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Zn_clus PF00172.18 EIM86804.1 - 5.3e-27 93.7 91.5 2.1e-08 34.1 11.8 5.2 4 1 1 5 5 5 5 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas_GSU0054 PF09609.10 EIM86805.1 - 0.0014 17.4 0.0 0.062 12.0 0.0 2.1 2 0 0 2 2 2 2 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) PBP1_TM PF14812.6 EIM86805.1 - 0.038 14.4 3.6 0.48 10.8 0.1 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4451 PF14616.6 EIM86805.1 - 0.044 14.0 8.5 1.1 9.4 1.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) SIR2 PF02146.17 EIM86806.1 - 3.9e-30 105.1 0.0 5.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF364 PF04016.12 EIM86806.1 - 0.0026 17.4 0.0 0.009 15.6 0.0 1.8 2 0 0 2 2 2 1 Putative heavy-metal chelation WD40 PF00400.32 EIM86807.1 - 7.1e-22 77.3 18.4 0.0036 18.1 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EIM86807.1 - 0.0047 15.9 0.0 0.093 11.7 0.0 2.4 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CTD_bind PF04818.13 EIM86808.1 - 0.00067 20.4 0.0 0.0017 19.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PAP2 PF01569.21 EIM86809.1 - 1e-25 90.1 1.3 2.1e-25 89.0 0.9 1.7 2 0 0 2 2 2 1 PAP2 superfamily SNF2_N PF00176.23 EIM86810.1 - 9.7e-19 67.3 1.0 2.8e-14 52.6 0.1 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 EIM86810.1 - 1.5e-12 47.5 0.0 5.9e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 EIM86810.1 - 1.1e-06 28.9 0.0 3.1e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain A2L_zn_ribbon PF08792.10 EIM86810.1 - 0.06 13.1 1.7 0.16 11.8 1.7 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-C3HC4 PF00097.25 EIM86810.1 - 0.63 10.0 7.6 2.1 8.3 7.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM86810.1 - 1.8 8.7 6.1 1.6 8.8 3.7 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Zw10 PF06248.13 EIM86811.1 - 5.1e-19 68.2 0.0 2.9e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EIM86811.1 - 1.9e-07 31.0 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Methyltransf_16 PF10294.9 EIM86812.1 - 2.4e-13 50.2 0.0 5.1e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EIM86812.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 EIM86812.1 - 0.027 13.8 0.0 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G STN PF07660.14 EIM86812.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Methyltransf_25 PF13649.6 EIM86812.1 - 0.079 13.7 0.0 0.27 12.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Amino_oxidase PF01593.24 EIM86813.1 - 6.2e-23 81.8 0.0 7.9e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIM86813.1 - 7.8e-16 58.1 0.0 2.3e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM86813.1 - 2.6e-05 24.3 0.0 0.079 12.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EIM86813.1 - 0.0006 19.5 0.1 0.0018 17.9 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM86813.1 - 0.004 16.4 0.0 0.087 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Prenylcys_lyase PF07156.14 EIM86813.1 - 0.037 13.1 0.0 0.17 11.0 0.0 1.8 1 1 0 1 1 1 0 Prenylcysteine lyase Thi4 PF01946.17 EIM86813.1 - 0.067 12.4 0.0 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EIM86813.1 - 0.093 11.4 0.0 0.37 9.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein p450 PF00067.22 EIM86814.1 - 1.2e-59 202.3 0.0 1.7e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cript PF10235.9 EIM86816.1 - 1.6e-25 89.5 4.8 1.6e-25 89.5 4.8 1.9 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EIM86816.1 - 0.0088 16.0 11.0 0.031 14.3 6.5 2.4 1 1 1 2 2 2 1 Double zinc ribbon Gin PF10764.9 EIM86816.1 - 0.018 14.9 5.3 0.3 11.1 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zinc_ribbon_2 PF13240.6 EIM86816.1 - 0.019 14.6 15.5 1.8 8.4 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Rhodanese_C PF12368.8 EIM86816.1 - 0.025 14.9 5.8 0.052 13.9 1.8 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal zinc-ribbons_6 PF07191.12 EIM86816.1 - 0.035 14.1 7.4 0.38 10.8 3.6 2.2 2 0 0 2 2 2 0 zinc-ribbons DUF2039 PF10217.9 EIM86816.1 - 0.27 11.6 14.8 0.079 13.3 8.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-dskA_traR PF01258.17 EIM86816.1 - 0.4 10.7 8.5 4.3 7.4 0.0 3.6 2 1 2 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zf_UBZ PF18439.1 EIM86816.1 - 0.59 9.8 8.5 4.9 6.8 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DiS_P_DiS PF06750.13 EIM86816.1 - 0.6 10.3 5.4 0.58 10.3 1.3 2.2 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_15 PF17032.5 EIM86816.1 - 0.89 10.4 11.9 3 8.7 9.1 2.6 2 1 0 2 2 2 0 zinc-ribbon family PLATZ PF04640.14 EIM86816.1 - 1.3 9.7 8.9 1.5 9.5 2.3 2.9 2 1 1 3 3 3 0 PLATZ transcription factor PhnA_Zn_Ribbon PF08274.12 EIM86816.1 - 6.1 6.9 8.8 16 5.6 0.0 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon F-box-like PF12937.7 EIM86817.1 - 1.2e-06 28.3 0.6 2.2e-06 27.5 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM86817.1 - 8e-06 25.6 0.4 1.5e-05 24.7 0.4 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 EIM86817.1 - 0.00022 21.2 0.1 0.00056 19.9 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain F-box_4 PF15966.5 EIM86817.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 F-box TPR_11 PF13414.6 EIM86817.1 - 0.17 11.6 0.1 1.3 8.8 0.0 2.1 1 1 1 2 2 2 0 TPR repeat DnaJ PF00226.31 EIM86818.1 - 4e-25 87.7 0.4 8.2e-25 86.7 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 EIM86818.1 - 2e-24 85.9 0.0 4.5e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Apt1 PF10351.9 EIM86818.1 - 2.1 7.1 4.9 2.7 6.7 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EIM86818.1 - 2.7 6.4 6.6 3.6 6.0 6.6 1.1 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 EIM86818.1 - 8 4.5 12.4 12 4.0 12.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 F-box-like PF12937.7 EIM86819.1 - 1.3e-05 25.0 0.4 3.2e-05 23.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like ubiquitin PF00240.23 EIM86820.1 - 3.4e-34 116.4 0.5 3.4e-34 116.4 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EIM86820.1 - 3.8e-26 91.0 2.4 3.8e-26 91.0 2.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EIM86820.1 - 3.7e-16 58.7 0.6 7.9e-16 57.7 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIM86820.1 - 2.4e-05 24.7 0.3 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EIM86820.1 - 0.00031 20.8 0.6 0.00071 19.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EIM86820.1 - 0.0073 16.6 1.2 0.012 15.9 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EIM86820.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EIM86820.1 - 0.0085 16.6 0.8 0.012 16.2 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EIM86820.1 - 0.019 15.0 1.1 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4925 PF16272.5 EIM86820.1 - 0.036 13.5 0.2 0.049 13.1 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) IBR PF01485.21 EIM86820.1 - 0.039 14.2 0.4 0.069 13.4 0.4 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF971 PF06155.12 EIM86820.1 - 0.15 12.7 0.2 0.34 11.6 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF971) Rep_fac_C PF08542.11 EIM86821.1 - 2.1e-18 66.5 0.0 6.2e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EIM86821.1 - 3.5e-17 63.1 0.0 5.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EIM86821.1 - 1.7e-15 57.2 0.0 1.5e-11 44.3 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EIM86821.1 - 4.3e-09 36.6 0.0 1.3e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EIM86821.1 - 2.1e-07 30.9 0.0 7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EIM86821.1 - 1.7e-06 28.1 0.5 0.00021 21.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 EIM86821.1 - 1.7e-06 27.9 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EIM86821.1 - 5.4e-06 26.7 0.0 1.7e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 EIM86821.1 - 3.1e-05 24.0 0.0 6.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIM86821.1 - 5.5e-05 23.0 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EIM86821.1 - 5.5e-05 22.5 0.0 8.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EIM86821.1 - 8.4e-05 22.9 0.7 0.021 15.2 0.0 2.8 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EIM86821.1 - 9.2e-05 22.9 0.0 0.00045 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM86821.1 - 0.00026 21.3 0.4 0.18 12.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 EIM86821.1 - 0.00027 20.7 0.0 0.0006 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EIM86821.1 - 0.00029 20.9 0.0 0.0094 16.0 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EIM86821.1 - 0.00094 19.2 0.2 0.0067 16.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EIM86821.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EIM86821.1 - 0.0021 17.9 0.3 0.012 15.4 0.4 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 EIM86821.1 - 0.0035 16.8 0.1 0.21 11.0 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 EIM86821.1 - 0.0043 16.6 0.0 0.0086 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EIM86821.1 - 0.0088 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EIM86821.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MCM PF00493.23 EIM86821.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_28 PF13521.6 EIM86821.1 - 0.047 13.9 0.4 0.18 12.1 0.4 2.2 2 1 0 2 2 2 0 AAA domain TPR_6 PF13174.6 EIM86821.1 - 0.081 13.6 1.3 10 7.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ATPase_2 PF01637.18 EIM86821.1 - 0.084 12.8 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EIM86821.1 - 0.11 11.9 0.0 0.41 10.0 0.0 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.23 EIM86821.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF3861 PF12977.7 EIM86822.1 - 0.09 12.9 0.1 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) DUF3810 PF12725.7 EIM86822.1 - 0.15 11.4 0.5 0.22 10.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ribosomal_L17 PF01196.19 EIM86822.1 - 2 9.4 6.3 8 7.4 6.3 2.2 1 1 0 1 1 1 0 Ribosomal protein L17 ALS2CR11 PF15729.5 EIM86822.1 - 2.8 7.0 6.7 1.2 8.2 1.8 2.0 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 candidate 11 Pkinase PF00069.25 EIM86823.1 - 8.3e-09 35.2 0.0 2.4e-07 30.4 0.0 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM86823.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Actin PF00022.19 EIM86824.1 - 3e-115 385.1 0.0 1.4e-114 382.9 0.0 1.7 1 1 0 1 1 1 1 Actin DNA_pol_lambd_f PF10391.9 EIM86824.1 - 0.098 12.5 0.2 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda PQ-loop PF04193.14 EIM86825.1 - 1.8e-24 85.3 8.1 8.8e-16 57.4 0.2 3.2 3 0 0 3 3 3 2 PQ loop repeat Pkinase_fungal PF17667.1 EIM86826.1 - 1.9e-34 119.1 0.0 6.4e-24 84.5 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM86826.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 EIM86826.1 - 0.019 14.6 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 EIM86826.1 - 0.024 14.6 0.1 0.15 11.9 0.1 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM86826.1 - 0.1 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DNA_meth_N PF18284.1 EIM86826.1 - 0.19 11.7 0.2 0.51 10.3 0.2 1.7 1 0 0 1 1 1 0 DNA methylase N-terminal domain Sugar_tr PF00083.24 EIM86827.1 - 3.2e-107 359.2 17.7 3.7e-107 359.0 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM86827.1 - 5e-24 84.9 21.7 5.2e-22 78.3 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 EIM86827.1 - 0.26 10.7 6.5 6.1 6.3 2.6 2.7 2 1 0 2 2 2 0 Emopamil binding protein Prenyltrans PF00432.21 EIM86829.1 - 3.8e-32 109.7 8.7 1.1e-06 28.2 0.0 6.2 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EIM86829.1 - 0.032 13.3 0.0 3.2 6.8 0.0 2.7 2 1 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Adeno_PIX PF03955.14 EIM86830.1 - 0.0034 17.5 0.3 0.051 13.7 0.1 2.4 2 0 0 2 2 2 1 Adenovirus hexon-associated protein (IX) DUF2883 PF11097.8 EIM86830.1 - 0.088 12.9 0.0 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2883) Pkinase PF00069.25 EIM86832.1 - 2.8e-09 36.8 0.0 2.5e-06 27.0 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Glyco_hydro_99 PF16317.5 EIM86832.1 - 0.036 13.2 1.3 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 99 Pkinase_Tyr PF07714.17 EIM86832.1 - 0.051 12.9 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM86832.1 - 0.13 11.0 0.0 0.35 9.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase LisH PF08513.11 EIM86833.1 - 1.3e-06 28.2 0.1 2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 LisH START PF01852.19 EIM86834.1 - 2.3e-19 69.7 0.1 2.9e-11 43.2 0.0 3.1 4 0 0 4 4 4 2 START domain Phos_pyr_kin PF08543.12 EIM86835.1 - 6.7e-12 45.3 0.0 1.2e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EIM86835.1 - 2.8e-05 23.6 0.1 0.00014 21.3 0.0 2.1 2 1 1 3 3 3 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EIM86835.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate kinase DUF676 PF05057.14 EIM86836.1 - 1.3e-40 139.3 0.0 2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EIM86836.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 EIM86836.1 - 0.00078 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hamartin PF04388.12 EIM86836.1 - 0.019 13.6 1.1 0.027 13.2 1.1 1.1 1 0 0 1 1 1 0 Hamartin protein SesA PF17107.5 EIM86837.1 - 0.039 14.1 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PKcGMP_CC PF16808.5 EIM86837.1 - 0.076 12.9 0.4 0.076 12.9 0.4 3.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Nup54 PF13874.6 EIM86837.1 - 0.11 12.5 5.5 3.9 7.6 1.5 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 WXG100 PF06013.12 EIM86837.1 - 0.13 12.5 0.3 1.7 8.9 0.2 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Sec34 PF04136.15 EIM86837.1 - 0.22 11.4 7.9 0.68 9.8 0.1 2.6 3 0 0 3 3 3 0 Sec34-like family DUF641 PF04859.12 EIM86837.1 - 0.52 10.6 5.7 9.1 6.6 2.8 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 EIM86837.1 - 0.57 9.5 6.2 1.1 8.6 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 EIM86837.1 - 0.65 9.3 20.9 1.2 8.5 5.3 2.3 1 1 1 2 2 2 0 Tropomyosin TMPIT PF07851.13 EIM86837.1 - 0.75 9.0 2.5 1.6 7.9 2.5 1.6 1 1 0 1 1 1 0 TMPIT-like protein ATG16 PF08614.11 EIM86837.1 - 0.9 9.7 16.2 0.92 9.7 12.7 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 EIM86837.1 - 2.2 8.1 11.0 0.49 10.2 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 EIM86837.1 - 4.5 8.0 10.2 1.4 9.6 3.7 2.6 2 0 0 2 2 2 0 Initiation control protein YabA COG6 PF06419.11 EIM86837.1 - 4.9 5.2 7.3 1.5 7.0 1.6 2.1 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 TMF_DNA_bd PF12329.8 EIM86837.1 - 5.6 7.0 9.9 8.8 6.4 3.0 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 EIM86837.1 - 7.9 4.3 5.5 12 3.7 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 EIM86837.1 - 8.8 7.0 8.2 13 6.5 2.0 2.8 2 0 0 2 2 2 0 SlyX GrpE PF01025.19 EIM86837.1 - 9.8 5.8 8.9 15 5.2 0.2 2.6 2 0 0 2 2 2 0 GrpE BrkDBD PF09607.10 EIM86838.1 - 0.058 13.2 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Brinker DNA-binding domain DOPA_dioxygen PF08883.11 EIM86840.1 - 3e-42 143.1 0.1 3.9e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PALP PF00291.25 EIM86841.1 - 1.8e-58 198.3 0.6 2.2e-58 198.0 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 EIM86842.1 - 1.1e-54 185.9 0.9 1.5e-54 185.4 0.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 EIM86844.1 - 1.2e-37 130.0 0.0 1.8e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 EIM86844.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EIM86844.1 - 0.034 14.9 0.0 0.21 12.3 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain DUF1758 PF05585.12 EIM86844.1 - 0.098 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Methyltransf_11 PF08241.12 EIM86845.1 - 4.7e-14 52.8 0.0 9.5e-14 51.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM86845.1 - 9.5e-13 48.7 0.0 4.2e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM86845.1 - 1.8e-12 47.3 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86845.1 - 1.8e-05 25.4 0.0 3.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM86845.1 - 9.3e-05 22.3 0.0 0.00053 19.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM86845.1 - 0.0013 18.1 0.3 0.68 9.2 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family NodS PF05401.11 EIM86845.1 - 0.0028 17.3 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EIM86845.1 - 0.028 14.4 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CbiK PF06180.11 EIM86845.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) GT-D PF08759.11 EIM86845.1 - 0.091 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Tmemb_14 PF03647.13 EIM86846.1 - 2.1e-16 60.4 4.7 2.7e-16 60.1 4.7 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C CCB1 PF12046.8 EIM86846.1 - 0.074 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B PQ-loop PF04193.14 EIM86847.1 - 1.5e-31 108.0 5.6 3.4e-17 62.0 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EIM86847.1 - 0.011 15.8 7.0 0.29 11.2 0.5 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF2561 PF10812.8 EIM86847.1 - 0.018 15.1 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) ER_lumen_recept PF00810.18 EIM86847.1 - 0.052 14.4 2.2 0.2 12.5 0.4 2.5 1 1 2 3 3 3 0 ER lumen protein retaining receptor 7TM_GPCR_Srw PF10324.9 EIM86847.1 - 0.095 12.0 1.9 0.2 10.9 1.9 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw LAB_N PF07578.11 EIM86847.1 - 1.1 9.4 7.9 2.8 8.1 1.3 2.5 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain MMS19_C PF12460.8 EIM86848.1 - 2e-110 369.9 1.2 2e-110 369.9 1.2 2.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EIM86848.1 - 3.3e-86 289.1 0.0 3.3e-86 289.1 0.0 3.1 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EIM86848.1 - 0.00024 21.5 7.8 0.15 12.6 0.1 7.6 10 0 0 10 10 10 1 HEAT-like repeat HEAT_2 PF13646.6 EIM86848.1 - 0.0017 18.7 5.3 9.3 6.7 0.1 5.8 6 0 0 6 6 6 1 HEAT repeats DUF3385 PF11865.8 EIM86848.1 - 0.0056 16.6 0.2 0.062 13.2 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Feld-I_B PF09252.10 EIM86848.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Allergen Fel d I-B chain HEAT PF02985.22 EIM86848.1 - 5.8 7.4 6.2 36 5.0 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat Phage_sheath_1 PF04984.14 EIM86849.1 - 0.005 16.7 0.3 4.6 7.1 0.0 2.8 2 1 0 2 2 2 2 Phage tail sheath protein subtilisin-like domain Laminin_II PF06009.12 EIM86849.1 - 0.02 14.9 3.0 2.5 8.1 0.0 3.2 3 0 0 3 3 3 0 Laminin Domain II Ku_PK_bind PF08785.11 EIM86849.1 - 0.088 13.0 0.2 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Ku C terminal domain like DUF948 PF06103.11 EIM86849.1 - 0.17 12.2 0.8 34 4.8 0.0 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) T3SSipB PF16535.5 EIM86849.1 - 4.3 7.8 10.5 17 5.8 0.0 3.4 3 0 0 3 3 3 0 Type III cell invasion protein SipB DUF3561 PF12084.8 EIM86850.1 - 0.13 12.3 7.4 0.099 12.7 5.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Paf1 PF03985.13 EIM86851.1 - 9.9e-66 222.5 0.1 1.3e-65 222.1 0.1 1.1 1 0 0 1 1 1 1 Paf1 DUF2975 PF11188.8 EIM86852.1 - 0.34 10.8 5.0 8.3 6.3 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) IF4E PF01652.18 EIM86853.1 - 1.5e-51 174.3 0.0 2.3e-37 128.3 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic initiation factor 4E Kei1 PF08552.11 EIM86854.1 - 2e-55 187.6 3.6 2.6e-55 187.3 3.6 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Phage_holin_3_6 PF07332.11 EIM86854.1 - 4.8 7.2 8.3 1.4 9.0 4.7 1.9 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zf-HIT PF04438.16 EIM86856.1 - 2.9e-06 27.1 9.7 4.2e-06 26.5 9.7 1.2 1 0 0 1 1 1 1 HIT zinc finger CRAL_TRIO PF00650.20 EIM86857.1 - 4.1e-29 101.4 0.0 5.8e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIM86857.1 - 0.0026 17.9 0.1 0.0071 16.5 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Cyto_heme_lyase PF01265.17 EIM86857.1 - 0.13 11.8 4.7 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase HABP4_PAI-RBP1 PF04774.15 EIM86857.1 - 3.9 8.4 7.3 7.7 7.4 7.3 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Aminotran_3 PF00202.21 EIM86858.1 - 9.4e-79 264.9 0.0 1.2e-78 264.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EIM86858.1 - 0.0054 16.0 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II HECT PF00632.25 EIM86859.1 - 1.7e-76 257.7 0.0 2.4e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Nse4-Nse3_bdg PF15412.6 EIM86859.1 - 0.055 13.6 1.1 0.21 11.7 1.1 2.0 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Arm PF00514.23 EIM86859.1 - 0.73 10.0 3.9 5.3 7.2 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PHF5 PF03660.14 EIM86860.1 - 1.9e-52 175.9 7.9 2.1e-52 175.7 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EIM86860.1 - 0.038 11.9 4.8 0.042 11.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EIM86860.1 - 0.42 10.7 15.0 1.6 8.8 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 EIM86860.1 - 2 8.8 17.7 0.37 11.1 2.7 2.6 1 1 1 2 2 2 0 C1 domain ZZ PF00569.17 EIM86861.1 - 1.7e-18 66.2 52.6 2.7e-07 30.3 4.4 6.3 6 0 0 6 6 6 6 Zinc finger, ZZ type PB1 PF00564.24 EIM86861.1 - 4.9e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 EIM86861.1 - 1.4e-05 25.3 44.8 0.015 15.6 7.8 5.8 6 0 0 6 6 6 4 C1 domain DPBB_1 PF03330.18 EIM86862.1 - 1e-05 25.7 0.3 1e-05 25.7 0.3 3.4 4 1 0 4 4 4 1 Lytic transglycolase CCAP PF11105.8 EIM86862.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a DHHC PF01529.20 EIM86863.1 - 3.1e-20 72.7 8.2 4.1e-20 72.3 1.2 3.2 2 2 0 2 2 2 1 DHHC palmitoyltransferase DSPc PF00782.20 EIM86864.1 - 1.4e-29 102.6 0.0 1.7e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIM86864.1 - 0.0044 16.6 0.1 0.0055 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SSF PF00474.17 EIM86864.1 - 0.021 13.7 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family TatD_DNase PF01026.21 EIM86864.1 - 0.034 13.5 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase DUF952 PF06108.12 EIM86865.1 - 1.4e-17 63.4 0.0 2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Amidase PF01425.21 EIM86866.1 - 5e-106 355.4 0.0 5.9e-106 355.1 0.0 1.0 1 0 0 1 1 1 1 Amidase RRM_1 PF00076.22 EIM86867.1 - 2.6e-31 107.2 0.9 3.8e-15 55.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM86867.1 - 5.7e-07 29.6 0.0 0.0023 18.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EIM86867.1 - 0.00012 21.9 0.0 0.97 9.3 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif GFO_IDH_MocA PF01408.22 EIM86868.1 - 1.9e-21 77.1 0.0 2.7e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EIM86868.1 - 0.00072 19.6 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 EIM86868.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EIM86868.1 - 0.2 12.4 0.0 0.38 11.5 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase p450 PF00067.22 EIM86870.1 - 7.2e-63 212.9 0.0 2.2e-62 211.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 HIT PF01230.23 EIM86871.1 - 0.026 15.2 0.0 3.2 8.6 0.0 2.7 3 0 0 3 3 3 0 HIT domain Med4 PF10018.9 EIM86872.1 - 2.7e-22 79.4 0.0 3.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 UPF0242 PF06785.11 EIM86872.1 - 0.043 13.9 0.9 0.062 13.4 0.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CortBP2 PF09727.9 EIM86872.1 - 0.051 13.5 1.3 0.07 13.0 1.3 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF4659 PF15558.6 EIM86872.1 - 0.1 11.4 5.5 0.38 9.6 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4659) Med21 PF11221.8 EIM86872.1 - 5.6 7.2 6.1 1.1 9.5 2.0 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex AAA_12 PF13087.6 EIM86873.1 - 5.3e-36 124.1 0.0 8.6e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM86873.1 - 2.3e-31 109.5 0.1 3e-14 53.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EIM86873.1 - 1.1e-07 32.3 0.0 8.8e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM86873.1 - 1.5e-07 31.3 0.0 7.1e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain zf-CCCH_4 PF18044.1 EIM86873.1 - 0.0021 17.8 3.6 0.0021 17.8 3.6 4.3 5 0 0 5 5 5 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EIM86873.1 - 0.0065 16.5 18.2 0.24 11.5 6.4 3.1 2 0 0 2 2 2 2 Zinc finger domain DUF2075 PF09848.9 EIM86873.1 - 0.058 12.6 0.0 0.16 11.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SQHop_cyclase_N PF13249.6 EIM86874.1 - 8.4e-50 169.5 0.4 1.8e-43 148.7 0.0 3.4 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EIM86874.1 - 1.1e-45 156.1 4.3 4.6e-43 147.5 1.5 3.0 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EIM86874.1 - 5.3e-36 122.0 7.9 3.8e-10 39.3 0.0 7.6 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EIM86874.1 - 0.00029 20.3 0.2 0.22 10.8 0.0 4.2 3 1 1 5 5 5 1 Pectic acid lyase TED_complement PF07678.14 EIM86874.1 - 0.051 12.6 2.2 0.076 12.0 0.3 2.2 2 2 0 2 2 2 0 A-macroglobulin TED domain Actin PF00022.19 EIM86875.1 - 1.6e-31 109.3 0.0 6.1e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 Actin Ribosomal_L7Ae PF01248.26 EIM86876.1 - 2.2e-21 75.4 0.0 2.5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HTH_IclR PF09339.10 EIM86876.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain SET PF00856.28 EIM86877.1 - 3.8e-08 33.9 0.2 6.2e-07 29.9 0.1 2.0 1 1 1 2 2 2 1 SET domain Vma12 PF11712.8 EIM86878.1 - 1.6e-12 47.7 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF5337 PF17272.2 EIM86878.1 - 8e-05 22.4 3.0 0.00014 21.6 3.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5337) PBP_N PF17093.5 EIM86878.1 - 6 7.1 8.3 2.5 8.4 0.9 3.0 1 1 2 3 3 3 0 Penicillin-binding protein N-terminus WW PF00397.26 EIM86879.1 - 0.0019 18.2 6.5 0.0019 18.2 6.5 2.0 2 0 0 2 2 2 1 WW domain PMM PF03332.13 EIM86880.1 - 1.1e-108 362.1 0.7 1.3e-108 361.9 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EIM86880.1 - 0.00019 21.3 0.0 0.00064 19.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EIM86880.1 - 0.021 14.4 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 EIM86880.1 - 0.043 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase F-box-like PF12937.7 EIM86881.1 - 3.3e-07 30.1 0.1 9.5e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EIM86881.1 - 7.8e-05 22.4 4.7 0.21 11.4 0.0 4.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EIM86881.1 - 0.00069 20.0 0.2 5.4 7.6 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) bVLRF1 PF18826.1 EIM86882.1 - 4.4e-64 214.9 0.0 7.4e-64 214.1 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor SurE PF01975.17 EIM86883.1 - 9.1e-37 126.7 2.9 1.3e-36 126.3 2.9 1.2 1 0 0 1 1 1 1 Survival protein SurE DNA_pol_B PF00136.21 EIM86884.1 - 1.6e-150 501.8 0.4 2.2e-150 501.4 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EIM86884.1 - 9.3e-90 301.1 0.0 1.4e-89 300.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EIM86884.1 - 7.9e-18 64.7 6.3 2e-17 63.4 6.3 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EIM86884.1 - 6.8e-05 21.9 0.5 0.0003 19.8 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EIM86884.1 - 0.00022 21.0 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EIM86884.1 - 0.025 14.6 0.2 0.13 12.3 0.2 2.1 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 EIM86884.1 - 0.088 12.5 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 3'-5' exonuclease DUF1476 PF07345.11 EIM86884.1 - 0.15 12.4 0.7 7 7.1 0.3 2.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta C1_1 PF00130.22 EIM86884.1 - 2.5 8.1 5.3 1.3 9.0 1.9 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ-X PF14308.6 EIM86885.1 - 7.7e-61 205.2 0.4 7.7e-61 205.2 0.4 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EIM86885.1 - 6.4e-25 87.1 2.0 6.4e-25 87.1 2.0 2.1 2 0 0 2 2 2 1 DnaJ domain Hamartin PF04388.12 EIM86885.1 - 0.091 11.4 8.7 0.16 10.6 8.7 1.3 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 EIM86885.1 - 0.21 10.2 5.2 3 6.4 6.8 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Spidroin_N PF16763.5 EIM86885.1 - 1.1 9.4 5.4 7.9 6.5 0.1 2.7 3 0 0 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term Herpes_DNAp_acc PF04929.12 EIM86885.1 - 1.2 8.0 12.3 2.1 7.2 12.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_M20 PF01546.28 EIM86886.1 - 2.7e-10 40.3 0.1 4.8e-10 39.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM86886.1 - 1.9e-09 37.4 0.0 4.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain T2SSM_b PF10741.9 EIM86888.1 - 0.15 11.9 0.3 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Actin PF00022.19 EIM86889.1 - 4.3e-26 91.5 0.0 1.8e-10 40.0 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 EIM86889.1 - 4.3e-11 42.6 0.0 3.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 EIM86889.1 - 1.7e-05 23.8 1.2 0.0077 15.1 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EIM86889.1 - 0.0059 17.0 0.1 0.064 13.7 0.1 2.2 2 0 0 2 2 2 1 Cell division protein FtsA DUF3552 PF12072.8 EIM86890.1 - 0.017 14.5 3.1 0.032 13.6 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FOXP-CC PF16159.5 EIM86892.1 - 0.00039 21.0 0.3 0.00052 20.6 0.3 1.3 1 0 0 1 1 1 1 FOXP coiled-coil domain DUF2110 PF09883.9 EIM86892.1 - 0.0068 16.0 0.0 0.0078 15.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2110) zf-C2H2 PF00096.26 EIM86892.1 - 0.017 15.5 1.4 0.033 14.7 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EIM86892.1 - 0.034 14.4 0.0 0.04 14.2 0.0 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon YabA PF06156.13 EIM86892.1 - 0.17 12.6 0.9 10 6.8 0.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA RCC1 PF00415.18 EIM86894.1 - 1.1e-16 61.1 6.3 0.00063 20.3 0.1 5.8 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIM86894.1 - 7.2e-12 44.8 15.0 6e-07 29.1 0.4 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EIM86894.1 - 8.5e-05 22.4 0.3 0.00017 21.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM86894.1 - 0.00041 20.2 0.3 0.00077 19.3 0.3 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EIM86894.1 - 0.006 17.1 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A GST_N_3 PF13417.6 EIM86895.1 - 7.2e-13 48.8 0.0 1.6e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM86895.1 - 9.1e-10 38.7 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM86895.1 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM86895.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM86895.1 - 0.0017 18.6 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM86895.1 - 0.0093 16.3 0.0 0.043 14.1 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain End_N_terminal PF12218.8 EIM86895.1 - 0.046 13.4 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase PAS_4 PF08448.10 EIM86895.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold FAT PF02259.23 EIM86896.1 - 5.6e-122 407.3 7.7 5.6e-122 407.3 7.7 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EIM86896.1 - 1.3e-69 234.8 0.1 5.3e-69 232.8 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EIM86896.1 - 9.1e-59 198.0 3.0 2.9e-55 186.6 0.1 5.5 5 1 0 6 6 6 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EIM86896.1 - 3e-38 130.2 0.2 3e-38 130.2 0.2 4.1 5 0 0 5 5 5 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EIM86896.1 - 1e-15 57.8 5.3 0.00029 21.2 0.0 9.0 8 2 0 9 9 8 3 HEAT repeats FATC PF02260.20 EIM86896.1 - 1.8e-15 56.5 1.6 4.2e-15 55.3 1.6 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EIM86896.1 - 1.3e-13 49.9 9.1 0.053 13.8 0.0 11.1 11 0 0 11 11 11 1 HEAT repeat HEAT_EZ PF13513.6 EIM86896.1 - 4e-09 36.8 9.1 0.0089 16.5 0.0 10.7 10 2 2 12 12 12 1 HEAT-like repeat Cnd1 PF12717.7 EIM86896.1 - 2.5e-06 27.6 2.9 0.2 11.7 0.0 5.5 4 2 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 EIM86896.1 - 2e-05 25.0 0.0 0.12 12.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Adaptin_N PF01602.20 EIM86896.1 - 2.2e-05 23.2 1.4 0.069 11.7 0.6 4.1 1 1 1 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.8 EIM86896.1 - 0.00046 19.8 0.9 2.6 7.6 0.0 5.2 5 2 0 6 6 6 1 CLASP N terminal RTP1_C1 PF10363.9 EIM86896.1 - 0.002 18.3 2.0 1.7 8.9 0.0 5.5 4 1 2 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 EIM86896.1 - 0.0023 17.1 9.1 6.3 5.8 0.0 7.2 7 1 2 9 9 9 2 Interferon-related developmental regulator (IFRD) Cohesin_HEAT PF12765.7 EIM86896.1 - 0.0025 18.1 2.7 0.11 12.9 0.0 3.5 3 0 0 3 3 2 1 HEAT repeat associated with sister chromatid cohesion TPR_7 PF13176.6 EIM86896.1 - 0.0041 17.1 2.6 1.2 9.3 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TAF6_C PF07571.13 EIM86896.1 - 0.018 15.3 2.1 8.4 6.8 0.0 4.8 5 0 0 5 5 3 0 TAF6 C-terminal HEAT repeat domain ANAPC3 PF12895.7 EIM86896.1 - 0.05 13.8 0.5 18 5.6 0.0 3.1 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EIM86896.1 - 0.061 13.5 0.2 94 3.5 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat UME PF08064.13 EIM86896.1 - 0.07 13.1 6.8 3.2 7.7 0.0 5.1 5 1 0 5 5 4 0 UME (NUC010) domain Polysacc_deac_1 PF01522.21 EIM86898.1 - 4e-26 91.3 0.0 7e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EIM86898.1 - 0.0054 16.0 0.0 0.0081 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2316 PF10078.9 EIM86898.1 - 0.2 11.9 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) CNH PF00780.22 EIM86899.1 - 1.4e-69 234.8 0.0 2.1e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EIM86899.1 - 5.5e-39 133.4 0.1 2.7e-38 131.1 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EIM86899.1 - 3.5e-37 128.4 0.0 5.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EIM86899.1 - 2.6e-12 46.6 0.1 5.6e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EIM86899.1 - 0.012 15.4 0.8 0.3 10.9 0.1 3.2 3 1 0 3 3 3 0 Pleckstrin homology domain Pyridox_ox_2 PF12900.7 EIM86900.1 - 4.5e-30 104.5 0.0 8.5e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PH_12 PF16457.5 EIM86901.1 - 5e-34 117.7 0.0 8.3e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 EIM86901.1 - 5.6e-27 95.0 0.0 9.6e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 EIM86901.1 - 1.1e-26 93.7 0.0 3.8e-26 91.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Sec1 PF00995.23 EIM86902.1 - 2e-129 433.4 0.0 2.4e-129 433.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family BRAP2 PF07576.12 EIM86903.1 - 8.6e-30 102.9 0.0 1.5e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EIM86903.1 - 1.9e-19 69.7 3.2 4.9e-19 68.4 3.2 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EIM86903.1 - 2.3e-08 34.2 9.1 2.3e-08 34.2 9.1 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM86903.1 - 5.6e-06 26.1 8.9 5.6e-06 26.1 8.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM86903.1 - 9.9e-06 25.2 4.5 2.8e-05 23.7 4.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EIM86903.1 - 3.4e-05 24.0 5.6 3.4e-05 24.0 5.6 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EIM86903.1 - 5.7e-05 22.9 7.0 0.00014 21.6 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM86903.1 - 9.4e-05 22.4 5.7 0.00033 20.6 5.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger RRM_1 PF00076.22 EIM86903.1 - 0.00022 21.0 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 EIM86903.1 - 0.00027 21.0 0.7 0.00027 21.0 0.7 1.6 2 0 0 2 2 2 1 SPX domain zf-RING_5 PF14634.6 EIM86903.1 - 0.00075 19.4 6.3 0.00075 19.4 6.3 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIM86903.1 - 0.0011 18.8 6.7 0.0011 18.8 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LPP PF04728.13 EIM86903.1 - 0.032 14.6 1.3 0.14 12.5 1.3 2.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper zf-ANAPC11 PF12861.7 EIM86903.1 - 0.043 13.9 6.0 0.092 12.8 6.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBP_var PF17807.1 EIM86903.1 - 0.043 13.6 0.4 0.11 12.3 0.4 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger DivIC PF04977.15 EIM86903.1 - 0.059 13.1 14.0 0.058 13.2 3.6 2.7 2 1 0 2 2 2 0 Septum formation initiator zf-RING_4 PF14570.6 EIM86903.1 - 0.077 12.8 5.8 0.21 11.4 5.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FlaC_arch PF05377.11 EIM86903.1 - 0.14 12.5 2.1 4.7 7.7 0.6 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Folliculin PF11704.8 EIM86903.1 - 2.2 8.1 4.2 3.9 7.3 4.2 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Rootletin PF15035.6 EIM86903.1 - 2.3 8.2 22.6 2.6 8.0 6.6 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion XRN_M PF17846.1 EIM86903.1 - 6.5 5.6 12.7 10 4.9 12.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain NUDIX PF00293.28 EIM86904.1 - 8.8e-11 42.0 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_3 PF07859.13 EIM86905.1 - 6.1e-11 42.6 0.0 3.6e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM86905.1 - 7.6e-05 21.8 0.1 0.0014 17.6 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 EIM86905.1 - 0.00032 19.7 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EIM86905.1 - 0.0019 17.3 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 EIM86905.1 - 0.002 18.8 0.2 0.0023 18.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM86905.1 - 0.084 12.1 0.0 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 F-box-like PF12937.7 EIM86907.1 - 7.9e-12 44.9 0.5 2.6e-11 43.2 0.5 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM86907.1 - 0.046 14.2 1.4 7.1 7.2 0.0 3.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) BLOC1_2 PF10046.9 EIM86907.1 - 0.22 11.8 0.1 0.42 10.9 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 F-box PF00646.33 EIM86907.1 - 0.98 9.4 4.5 36 4.4 4.5 3.0 1 1 0 1 1 1 0 F-box domain Carn_acyltransf PF00755.20 EIM86908.1 - 5.7e-181 603.1 0.0 6.4e-181 602.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase COesterase PF00135.28 EIM86909.1 - 1.2e-87 295.0 0.0 5.4e-87 292.8 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM86909.1 - 0.00021 21.2 0.2 0.00086 19.2 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM86909.1 - 0.0004 19.9 0.1 0.00069 19.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_76 PF03663.14 EIM86910.1 - 1.4e-38 133.4 20.5 1.6e-38 133.2 20.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_18 PF00704.28 EIM86911.1 - 5.8e-13 49.3 0.2 1.6e-12 47.8 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Ribosomal_L37ae PF01780.19 EIM86912.1 - 1.3e-40 137.3 11.2 1.5e-40 137.2 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EIM86912.1 - 0.00047 20.2 1.4 0.00066 19.8 1.4 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EIM86912.1 - 0.0046 16.9 2.1 0.0078 16.2 2.1 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.12 EIM86912.1 - 0.007 16.2 0.7 0.0098 15.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-BED PF02892.15 EIM86912.1 - 0.032 14.3 3.9 1.9 8.5 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger zf-FCS PF06467.14 EIM86912.1 - 0.041 13.8 1.1 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.6 EIM86912.1 - 0.094 13.2 4.5 2.4 8.7 0.8 2.3 1 1 1 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 EIM86912.1 - 0.12 12.8 2.5 0.59 10.5 2.7 1.8 1 1 0 1 1 1 0 C1 domain zf-Sec23_Sec24 PF04810.15 EIM86912.1 - 1.4 9.0 4.6 5.3 7.2 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger adh_short PF00106.25 EIM86913.1 - 7.2e-43 146.3 0.0 1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM86913.1 - 1.1e-25 90.6 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EIM86913.1 - 2e-06 27.4 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EIM86913.1 - 3.1e-05 24.0 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EIM86913.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding zf-CCCH PF00642.24 EIM86914.1 - 5.1e-11 42.2 22.3 6.9e-05 22.6 0.8 5.2 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EIM86914.1 - 0.00012 22.3 10.0 0.004 17.3 0.1 3.5 1 1 2 3 3 3 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 EIM86914.1 - 0.002 18.1 25.6 1.2 9.2 1.4 5.9 5 1 0 5 5 5 4 Zinc finger domain DUF1192 PF06698.11 EIM86914.1 - 0.11 12.6 0.5 0.23 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Torus PF16131.5 EIM86914.1 - 2.3 8.9 19.0 3 8.6 0.4 4.5 1 1 3 4 4 4 0 Torus domain Nop14 PF04147.12 EIM86914.1 - 8.6 4.4 11.3 12 4.0 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1712 PF08217.11 EIM86915.1 - 6.3e-18 64.6 0.0 9.2e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Dak1 PF02733.17 EIM86916.1 - 3.1e-111 371.2 0.2 5e-111 370.5 0.2 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EIM86916.1 - 1.8e-44 151.7 4.2 3.2e-44 150.9 4.2 1.4 1 0 0 1 1 1 1 DAK2 domain UCH PF00443.29 EIM86918.1 - 1.8e-69 234.1 0.0 2.4e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EIM86918.1 - 1.5e-14 54.4 0.0 4.1e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EIM86918.1 - 4.6e-13 49.5 0.0 1.6e-05 24.7 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pro-kuma_activ PF09286.11 EIM86919.1 - 3e-36 124.9 0.0 1.9e-35 122.2 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Sugar_tr PF00083.24 EIM86920.1 - 9.7e-130 433.4 22.7 1.1e-129 433.2 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM86920.1 - 1.8e-24 86.4 33.9 5.4e-17 61.7 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ytp1 PF10355.9 EIM86922.1 - 9.5e-55 185.8 21.4 6.6e-53 179.7 21.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EIM86922.1 - 1e-27 95.9 1.6 1e-27 95.9 1.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cellulase PF00150.18 EIM86923.1 - 5.2e-12 45.8 0.0 1.6e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2284 PF10050.9 EIM86923.1 - 0.034 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Amidase PF01425.21 EIM86924.1 - 1.9e-106 356.7 0.8 2.2e-106 356.5 0.8 1.0 1 0 0 1 1 1 1 Amidase CAP_GLY PF01302.25 EIM86925.1 - 1.3e-24 86.0 2.4 2.3e-24 85.2 2.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EIM86925.1 - 2.2e-24 85.7 0.1 3.6e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EIM86925.1 - 0.00032 20.4 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Pyridoxal_deC PF00282.19 EIM86926.1 - 1.7e-70 237.6 0.0 2.4e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EIM86926.1 - 0.00073 18.6 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V CN_hydrolase PF00795.22 EIM86927.1 - 2.5e-33 115.5 0.0 3.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lipase_3 PF01764.25 EIM86928.1 - 4.6e-24 84.9 0.1 5.9e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EIM86928.1 - 0.0062 16.2 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EIM86928.1 - 0.038 14.6 0.1 0.044 14.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM86928.1 - 0.063 12.9 0.1 0.074 12.7 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold M20_dimer PF07687.14 EIM86928.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase dimerisation domain COesterase PF00135.28 EIM86929.1 - 1.6e-87 294.5 0.0 1.2e-85 288.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 EIM86929.1 - 0.00036 20.1 0.2 0.00064 19.3 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EIM86929.1 - 0.016 15.1 0.1 0.051 13.4 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EIM86930.1 - 4.7e-87 293.0 0.0 1e-85 288.6 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM86930.1 - 0.00018 21.4 0.2 0.00088 19.2 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM86930.1 - 0.00024 20.7 0.2 0.0004 19.9 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EIM86931.1 - 5.2e-89 299.4 0.0 2.5e-87 293.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM86931.1 - 0.002 18.0 0.0 0.0043 16.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM86931.1 - 0.014 14.8 0.2 0.024 14.1 0.2 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pro_dh PF01619.18 EIM86932.1 - 6.1e-52 177.0 0.0 2.6e-25 89.6 0.0 3.0 2 1 0 2 2 2 2 Proline dehydrogenase AP_endonuc_2 PF01261.24 EIM86932.1 - 0.11 11.9 0.0 1.4 8.4 0.0 2.3 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF3446 PF11928.8 EIM86932.1 - 0.39 11.1 24.0 5.1 7.5 10.8 3.4 3 0 0 3 3 3 0 Early growth response N-terminal domain Pheromone PF08015.11 EIM86932.1 - 1.6 9.8 9.6 5.1 8.2 3.1 2.9 2 0 0 2 2 2 0 Fungal mating-type pheromone HSF_DNA-bind PF00447.17 EIM86933.1 - 5.3e-32 110.3 1.6 5.3e-32 110.3 1.6 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding F-box-like PF12937.7 EIM86934.1 - 4.3e-05 23.3 1.7 8.2e-05 22.4 0.8 2.0 2 0 0 2 2 2 1 F-box-like Tom37 PF10568.9 EIM86935.1 - 0.034 14.4 0.2 0.052 13.9 0.2 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF4407 PF14362.6 EIM86935.1 - 0.96 8.7 11.0 1.3 8.3 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRCT_2 PF16589.5 EIM86936.1 - 0.032 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Mt_ATP-synt_B PF05405.14 EIM86937.1 - 2.5e-40 137.8 11.5 3e-40 137.5 11.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5623 PF18536.1 EIM86937.1 - 0.18 12.1 4.4 0.17 12.1 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5623) Cortex-I_coil PF09304.10 EIM86937.1 - 0.19 11.9 5.8 0.11 12.7 3.4 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil Reprolysin PF01421.19 EIM86937.1 - 0.2 11.6 2.9 0.26 11.2 2.9 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease SLATT_1 PF18181.1 EIM86937.1 - 0.37 10.7 7.2 0.26 11.2 5.6 1.6 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DASH_Duo1 PF08651.10 EIM86937.1 - 0.52 10.1 7.9 3.1 7.6 0.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 Dynamin_M PF01031.20 EIM86938.1 - 2.6e-107 358.3 0.0 4.8e-107 357.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EIM86938.1 - 1.5e-53 181.3 0.0 2.8e-53 180.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EIM86938.1 - 1.2e-29 102.3 2.1 2.9e-29 101.1 0.7 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EIM86938.1 - 0.00015 21.8 0.1 0.0011 19.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.8 EIM86938.1 - 0.028 14.6 0.1 0.19 11.9 0.0 2.2 2 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit BCS1_N PF08740.11 EIM86939.1 - 2.9e-45 154.6 2.0 5.3e-45 153.7 2.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EIM86939.1 - 5.7e-15 55.9 0.0 1.6e-13 51.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM86939.1 - 0.0001 22.7 0.6 0.00031 21.2 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EIM86939.1 - 0.0052 17.0 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EIM86939.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EIM86939.1 - 0.01 15.0 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) YlbE PF14003.6 EIM86939.1 - 0.019 15.4 0.1 0.044 14.2 0.1 1.5 1 0 0 1 1 1 0 YlbE-like protein AAA_22 PF13401.6 EIM86939.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EIM86939.1 - 0.061 13.9 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain MPM1 PF17234.2 EIM86939.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 AAA_7 PF12775.7 EIM86939.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EIM86939.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.11 EIM86939.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM86939.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EIM86939.1 - 0.11 11.8 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EIM86939.1 - 0.11 12.3 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 EIM86939.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SYS1 PF09801.9 EIM86940.1 - 1.4e-25 90.2 2.4 8.1e-19 68.2 3.3 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DPPIV_N PF00930.21 EIM86941.1 - 3.1e-87 292.6 0.4 4.5e-87 292.1 0.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EIM86941.1 - 5.7e-42 143.6 1.8 8.9e-42 143.0 1.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EIM86941.1 - 0.00013 21.6 2.0 0.00033 20.3 1.9 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EIM86941.1 - 0.00019 21.1 0.1 0.00033 20.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM86941.1 - 0.00097 19.8 0.6 0.00097 19.8 0.6 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 EIM86941.1 - 0.027 13.1 0.0 0.054 12.2 0.0 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) LIP PF03583.14 EIM86941.1 - 0.14 11.5 0.1 0.49 9.7 0.1 1.8 2 0 0 2 2 2 0 Secretory lipase SH3BP5 PF05276.14 EIM86942.1 - 0.069 12.9 0.1 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Nro1 PF12753.7 EIM86942.1 - 0.17 10.8 0.6 0.71 8.8 0.3 1.9 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 Transketolase_N PF00456.21 EIM86943.1 - 4e-15 55.6 0.9 4.5e-14 52.1 0.9 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EIM86943.1 - 5.5e-07 29.5 0.0 9.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EIM86943.1 - 1e-05 25.3 0.0 4.8e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.24 EIM86943.1 - 1.8e-05 24.5 0.2 4.2e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Mito_carr PF00153.27 EIM86944.1 - 5.9e-47 157.5 2.2 5.3e-19 67.9 0.0 4.0 3 2 0 3 3 3 3 Mitochondrial carrier protein DAGAT PF03982.13 EIM86945.1 - 3.2e-98 328.3 0.0 3.9e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF3429 PF11911.8 EIM86945.1 - 0.056 13.7 3.3 0.094 13.0 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) DUF3270 PF11674.8 EIM86945.1 - 0.63 10.3 3.2 1.2 9.4 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) AAA PF00004.29 EIM86946.1 - 2.2e-96 319.3 0.0 4e-47 159.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM86946.1 - 3.7e-24 84.3 6.9 7.1e-12 44.9 0.4 3.2 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EIM86946.1 - 3.9e-18 65.4 0.6 3.5e-17 62.4 0.5 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EIM86946.1 - 2.3e-14 53.4 0.0 7.3e-06 25.8 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EIM86946.1 - 1.4e-13 51.3 0.0 1.6e-07 31.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EIM86946.1 - 5.7e-12 46.0 0.0 6.5e-06 26.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 EIM86946.1 - 1.9e-11 44.1 0.3 2.1e-05 24.5 0.1 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 EIM86946.1 - 3e-11 42.9 0.0 6.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 EIM86946.1 - 4.5e-11 43.4 0.1 0.0012 19.2 0.0 4.4 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.13 EIM86946.1 - 1.7e-09 37.3 0.0 0.0016 17.8 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EIM86946.1 - 3.7e-09 37.0 0.2 0.021 15.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EIM86946.1 - 1.4e-07 31.4 0.3 3.3e-06 27.0 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 EIM86946.1 - 4.5e-07 29.5 0.4 0.036 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EIM86946.1 - 5.3e-07 30.0 0.0 0.022 15.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 EIM86946.1 - 6.7e-07 29.2 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EIM86946.1 - 8.9e-07 29.0 0.0 0.018 15.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EIM86946.1 - 9e-07 29.5 0.0 0.037 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EIM86946.1 - 1.2e-06 28.1 0.4 0.51 9.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 EIM86946.1 - 3e-06 26.9 0.1 0.017 14.6 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EIM86946.1 - 3.2e-06 26.4 0.2 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EIM86946.1 - 7.1e-06 25.7 1.5 0.98 9.0 0.0 3.6 2 2 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EIM86946.1 - 7.4e-06 25.8 0.1 0.13 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 EIM86946.1 - 8.7e-06 25.5 0.0 0.19 11.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 EIM86946.1 - 9.2e-06 25.0 0.0 0.0051 16.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EIM86946.1 - 1.4e-05 25.6 0.0 0.056 14.0 0.0 3.6 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 EIM86946.1 - 1.5e-05 24.9 0.0 0.08 12.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_28 PF13521.6 EIM86946.1 - 1.6e-05 25.2 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EIM86946.1 - 0.0001 22.4 0.4 0.081 12.9 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EIM86946.1 - 0.00013 22.0 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EIM86946.1 - 0.00014 21.4 0.3 0.37 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 EIM86946.1 - 0.00015 22.2 0.0 0.61 10.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EIM86946.1 - 0.00016 21.6 1.2 0.95 9.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 EIM86946.1 - 0.0002 21.2 0.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EIM86946.1 - 0.00023 21.1 0.4 2.4 8.0 0.0 3.7 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EIM86946.1 - 0.00071 18.9 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EIM86946.1 - 0.0019 18.3 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EIM86946.1 - 0.0022 17.3 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 EIM86946.1 - 0.0023 17.9 0.2 1.2 9.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 EIM86946.1 - 0.0031 17.3 0.0 0.8 9.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EIM86946.1 - 0.0033 16.7 0.0 0.63 9.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 EIM86946.1 - 0.0035 17.1 1.1 2.6 7.7 0.1 2.7 3 0 0 3 3 2 1 AAA domain IPT PF01745.16 EIM86946.1 - 0.0089 15.4 0.1 2.4 7.5 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_19 PF13245.6 EIM86946.1 - 0.01 16.1 2.4 5.3 7.4 0.0 3.6 3 1 0 4 4 3 0 AAA domain UFD1 PF03152.14 EIM86946.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 T2SSE PF00437.20 EIM86946.1 - 0.021 13.9 0.0 0.86 8.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EIM86946.1 - 0.04 13.6 0.0 8.3 6.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 EIM86946.1 - 0.049 13.3 0.0 2 8.0 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.16 EIM86946.1 - 0.058 12.3 0.0 7.6 5.3 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase KAP_NTPase PF07693.14 EIM86946.1 - 0.076 12.2 0.3 0.88 8.7 0.0 2.6 2 2 2 4 4 4 0 KAP family P-loop domain Adeno_IVa2 PF02456.15 EIM86946.1 - 0.084 11.7 0.0 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 EIM86946.1 - 0.092 12.7 0.5 15 5.5 0.0 3.3 3 0 0 3 3 3 0 NTPase Torsin PF06309.11 EIM86946.1 - 0.22 11.6 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Torsin Hydin_ADK PF17213.3 EIM86946.1 - 2.6 8.3 6.7 1e+02 3.1 0.0 4.2 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain RhoGEF PF00621.20 EIM86948.1 - 2e-63 213.9 3.0 1.7e-33 116.4 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 EIM86948.1 - 1.2e-61 208.7 0.0 1.9e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EIM86948.1 - 4.1e-15 56.1 0.0 9.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 EIM86948.1 - 0.00098 19.0 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 PH domain DEP PF00610.21 EIM86948.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 EIM86948.1 - 0.045 14.2 0.0 1.8 9.1 0.0 3.3 2 1 0 2 2 2 0 PH domain Methyltransf_23 PF13489.6 EIM86949.1 - 1.5e-14 54.2 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86949.1 - 4.5e-13 49.8 0.0 1.4e-12 48.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM86949.1 - 5.4e-12 46.3 0.0 1.6e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM86949.1 - 6.9e-10 39.4 0.0 2.2e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM86949.1 - 3.1e-06 27.0 0.0 6.6e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EIM86949.1 - 0.0013 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EIM86949.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EIM86949.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EIM86949.1 - 0.0041 16.4 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 EIM86949.1 - 0.0067 16.3 0.0 0.24 11.2 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.11 EIM86949.1 - 0.012 15.3 0.0 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EIM86949.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EIM86949.1 - 0.085 13.9 0.0 0.29 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 EIM86949.1 - 0.12 11.9 0.0 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain APH PF01636.23 EIM86950.1 - 4.5e-11 43.1 1.4 7e-11 42.5 1.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM86950.1 - 2.6e-06 27.2 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase MHC_I_2 PF14586.6 EIM86950.1 - 0.0044 16.9 0.1 0.0067 16.3 0.1 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Kdo PF06293.14 EIM86950.1 - 0.013 14.9 0.1 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 EIM86950.1 - 0.095 11.5 0.0 4.9 5.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EIM86950.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 EIM86950.1 - 0.13 11.8 0.1 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family AAA PF00004.29 EIM86951.1 - 1.7e-59 200.0 0.0 7.5e-44 149.4 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EIM86951.1 - 1e-25 89.9 0.9 3.9e-25 88.1 0.9 2.1 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EIM86951.1 - 7.9e-16 57.6 0.1 1.8e-10 40.4 0.0 3.0 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EIM86951.1 - 4e-09 37.1 4.8 0.0091 16.4 0.1 4.4 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 EIM86951.1 - 1.2e-06 28.6 0.1 0.14 12.1 0.0 3.7 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) TsaE PF02367.17 EIM86951.1 - 2.8e-06 27.4 0.1 0.078 13.0 0.1 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EIM86951.1 - 5.3e-06 26.7 0.0 0.0017 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EIM86951.1 - 7.6e-06 26.2 4.2 0.26 11.6 0.4 4.6 3 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.17 EIM86951.1 - 1.2e-05 25.1 0.0 0.067 12.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 EIM86951.1 - 3.5e-05 23.6 0.0 0.0023 17.7 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EIM86951.1 - 4.2e-05 24.1 0.0 0.24 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EIM86951.1 - 7.8e-05 22.9 0.0 0.0082 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EIM86951.1 - 0.00017 20.9 0.1 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 EIM86951.1 - 0.00039 20.6 0.0 0.088 12.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 EIM86951.1 - 0.00061 19.1 0.2 0.95 8.7 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 EIM86951.1 - 0.0019 18.2 0.9 4.8 7.1 0.1 3.6 3 1 0 3 3 3 1 NACHT domain SKI PF01202.22 EIM86951.1 - 0.0019 18.3 0.1 0.61 10.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.18 EIM86951.1 - 0.0019 18.0 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EIM86951.1 - 0.0022 18.0 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EIM86951.1 - 0.0025 18.3 0.0 0.65 10.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 EIM86951.1 - 0.0038 17.6 0.0 0.94 9.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EIM86951.1 - 0.0043 17.0 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 EIM86951.1 - 0.0052 16.5 0.0 1.1 8.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EIM86951.1 - 0.0054 16.1 0.4 0.69 9.2 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 EIM86951.1 - 0.0056 16.6 0.0 0.033 14.2 0.0 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 EIM86951.1 - 0.0063 16.0 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF2075 PF09848.9 EIM86951.1 - 0.018 14.3 0.0 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 EIM86951.1 - 0.022 14.6 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 EIM86951.1 - 0.027 14.3 0.0 6 6.6 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein APS_kinase PF01583.20 EIM86951.1 - 0.041 13.8 0.3 2.2 8.1 0.1 3.0 2 1 1 3 3 3 0 Adenylylsulphate kinase AAA_24 PF13479.6 EIM86951.1 - 0.08 12.7 0.1 13 5.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EIM86951.1 - 0.088 12.6 0.2 1.3 8.8 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EIM86951.1 - 0.098 13.1 0.2 0.59 10.6 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EIM86951.1 - 0.11 12.1 4.8 1.3 8.5 0.1 3.4 2 1 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EIM86951.1 - 0.12 12.8 0.3 0.8 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIM86951.1 - 0.13 11.5 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EIM86951.1 - 0.15 12.0 0.2 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 NTPase Lipase_3 PF01764.25 EIM86952.1 - 6.9e-20 71.4 0.1 1e-19 70.8 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Glyco_hydro_76 PF03663.14 EIM86953.1 - 5.3e-44 151.2 22.2 6.5e-44 150.9 22.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EIM86953.1 - 8.5e-06 25.1 2.3 0.00023 20.4 0.1 2.2 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EIM86953.1 - 1.2e-05 24.9 0.9 0.046 13.2 0.0 2.8 1 1 1 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_47 PF01532.20 EIM86953.1 - 0.02 13.8 0.7 0.53 9.1 0.0 2.8 2 1 0 3 3 3 0 Glycosyl hydrolase family 47 Rab5-bind PF09311.11 EIM86955.1 - 5.1e-05 22.8 2.2 6.7e-05 22.4 2.2 1.1 1 0 0 1 1 1 1 Rabaptin-like protein T3SS_needle_E PF08988.10 EIM86955.1 - 0.011 15.8 3.2 0.019 15.1 0.6 2.3 1 1 2 3 3 3 0 Type III secretion system, cytoplasmic E component of needle MutS_IV PF05190.18 EIM86955.1 - 0.028 14.7 2.2 12 6.3 0.1 3.0 2 1 1 3 3 3 0 MutS family domain IV AAA_32 PF13654.6 EIM86955.1 - 0.079 11.7 0.1 0.097 11.4 0.1 1.0 1 0 0 1 1 1 0 AAA domain CREPT PF16566.5 EIM86955.1 - 0.13 12.5 1.9 0.2 11.8 1.9 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 EIM86955.1 - 0.16 12.1 1.6 0.24 11.6 1.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Methyltransf_23 PF13489.6 EIM86956.1 - 1.2e-24 87.0 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM86956.1 - 2.9e-20 72.7 0.0 4.9e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM86956.1 - 7.4e-16 58.6 0.0 1.4e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM86956.1 - 1.7e-13 50.7 0.0 6.8e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM86956.1 - 1.4e-12 48.2 0.0 3.2e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EIM86956.1 - 6.4e-09 35.5 0.0 1.5e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EIM86956.1 - 6.9e-07 28.5 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 EIM86956.1 - 0.00025 20.5 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EIM86956.1 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EIM86956.1 - 0.01 15.4 0.1 0.019 14.5 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EIM86956.1 - 0.011 15.3 0.1 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW TPMT PF05724.11 EIM86956.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EIM86956.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EIM86956.1 - 0.029 14.0 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.12 EIM86956.1 - 0.045 12.8 0.0 0.096 11.8 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase AdoMet_MTase PF07757.13 EIM86956.1 - 0.079 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Retrotran_gag_2 PF14223.6 EIM86958.1 - 5e-10 39.2 0.0 2.6e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF659 PF04937.15 EIM86959.1 - 0.00063 19.6 0.9 0.0014 18.5 0.0 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF 659) DUF2130 PF09903.9 EIM86960.1 - 0.024 13.9 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) THF_DHG_CYH PF00763.23 EIM86960.1 - 0.071 13.4 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 2OG-FeII_Oxy_3 PF13640.6 EIM86961.1 - 0.14 13.0 0.0 0.18 12.7 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF503 PF04456.12 EIM86962.1 - 0.086 12.7 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF503) CAF1 PF04857.20 EIM86963.1 - 0.048 12.8 0.0 0.049 12.8 0.0 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease DDE_3 PF13358.6 EIM86964.1 - 3.4e-05 23.6 0.1 4.6e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EIM86965.1 - 9.8e-18 64.4 0.0 9.7e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIM86965.1 - 7.1e-06 25.8 0.0 0.00012 21.9 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.15 EIM86966.1 - 1.9e-11 44.1 1.1 3.5e-11 43.2 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 EIM86966.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Autoind_synth PF00765.17 EIM86967.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Autoinducer synthase CFEM PF05730.11 EIM86967.1 - 2.9 8.1 7.3 19 5.4 0.2 2.6 2 1 1 3 3 3 0 CFEM domain HSP70 PF00012.20 EIM86968.1 - 8.3e-225 747.5 0.4 1.3e-224 746.8 0.4 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIM86968.1 - 2.6e-16 59.4 0.0 3.8e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 EIM86968.1 - 0.028 13.4 0.4 0.37 9.7 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF2059 PF09832.9 EIM86969.1 - 0.19 11.8 0.3 25 5.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) F-box-like PF12937.7 EIM86972.1 - 1.6e-07 31.1 0.5 3.6e-06 26.8 0.0 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM86972.1 - 1.2e-06 28.2 3.1 4.3e-05 23.3 0.1 3.2 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 EIM86973.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like Ldh_1_C PF02866.18 EIM86977.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Helitron_like_N PF14214.6 EIM86978.1 - 9.8e-24 84.6 0.0 1.4e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus tRNA_Me_trans PF03054.16 EIM86978.1 - 0.062 12.1 0.3 0.087 11.6 0.3 1.1 1 0 0 1 1 1 0 tRNA methyl transferase AAA_30 PF13604.6 EIM86980.1 - 3.6e-07 30.1 0.0 7.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 EIM86980.1 - 0.00019 20.7 0.7 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_19 PF13245.6 EIM86980.1 - 0.0024 18.2 1.5 0.0034 17.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain Glu-tRNAGln PF02686.15 EIM86980.1 - 0.011 16.1 0.7 0.03 14.6 0.7 1.8 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit AAA_16 PF13191.6 EIM86980.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EIM86980.1 - 0.014 15.7 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EIM86980.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EIM86980.1 - 0.17 12.0 3.0 0.64 10.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain CDK2AP PF09806.9 EIM86981.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DDE_1 PF03184.19 EIM86983.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EIM86985.1 - 3.8e-07 29.9 0.0 4.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1442 PF07279.11 EIM86985.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Rad52_Rad22 PF04098.15 EIM86986.1 - 0.031 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein LCM PF04072.14 EIM86986.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Cellulase PF00150.18 EIM86988.1 - 3.9e-48 164.3 0.1 5.9e-48 163.7 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EIM86988.1 - 1.4e-11 44.1 8.3 1.4e-11 44.1 8.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain SRP-alpha_N PF04086.13 EIM86988.1 - 2.6 7.9 5.2 3.8 7.3 5.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SPX PF03105.19 EIM86988.1 - 8.6 6.2 8.2 11 5.8 8.2 1.1 1 0 0 1 1 1 0 SPX domain MFS_1 PF07690.16 EIM86991.1 - 1.6e-21 76.6 31.2 1.6e-21 76.6 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EIM86991.1 - 0.00044 18.9 17.1 0.0013 17.4 8.3 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein Peptidase_U4 PF03419.13 EIM86991.1 - 6.1 6.0 18.7 0.032 13.5 7.5 2.3 2 1 0 2 2 2 0 Sporulation factor SpoIIGA FAD_binding_3 PF01494.19 EIM86992.1 - 2.6e-72 244.0 0.0 4.1e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM86992.1 - 2.3e-33 115.6 0.0 7.1e-33 114.0 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EIM86992.1 - 1.4e-06 27.3 0.3 2e-05 23.5 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM86992.1 - 8.2e-06 25.2 0.1 4.4e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM86992.1 - 2.6e-05 24.3 0.1 7.4e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM86992.1 - 0.00026 20.2 0.6 0.00045 19.4 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EIM86992.1 - 0.00074 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EIM86992.1 - 0.0013 17.9 0.4 0.0026 16.9 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EIM86992.1 - 0.0028 17.3 0.8 0.0076 15.9 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EIM86992.1 - 0.0043 17.0 0.1 0.0071 16.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EIM86992.1 - 0.0053 16.0 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM86992.1 - 0.0058 16.0 0.4 0.0085 15.5 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM86992.1 - 0.013 16.1 0.1 0.033 14.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM86992.1 - 0.021 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EIM86992.1 - 0.031 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 EIM86992.1 - 0.059 13.8 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EIM86992.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 EIM86992.1 - 0.091 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Asp PF00026.23 EIM86994.1 - 7e-35 120.9 2.0 2.7e-25 89.5 1.7 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM86994.1 - 1.9e-08 34.7 0.5 1.1e-06 29.0 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RTA1 PF04479.13 EIM86994.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RTA1 like protein DUF4646 PF15496.6 EIM86999.1 - 4.1e-27 95.3 0.0 8.5e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Bac_export_2 PF01312.19 EIM86999.1 - 2.2 7.4 5.0 3.3 6.8 5.0 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Git3 PF11710.8 EIM87000.1 - 1.8e-08 34.4 10.7 5.5e-08 32.8 10.7 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EIM87000.1 - 0.012 15.7 2.4 0.018 15.1 1.0 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 EIM87000.1 - 0.068 12.3 9.0 0.13 11.4 9.0 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor CobW_C PF07683.14 EIM87000.1 - 0.17 11.8 0.2 0.42 10.6 0.2 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain DUF3328 PF11807.8 EIM87001.1 - 6.6e-17 62.0 0.5 4.5e-16 59.3 0.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PARP PF00644.20 EIM87003.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain MCM_OB PF17207.3 EIM87003.1 - 1 9.2 10.2 0.75 9.7 0.8 2.8 2 1 0 2 2 2 0 MCM OB domain Ferric_reduct PF01794.19 EIM87005.1 - 0.018 15.1 9.9 0.019 15.0 8.0 2.1 1 1 0 1 1 1 0 Ferric reductase like transmembrane component SecY PF00344.20 EIM87006.1 - 1.4e-74 251.2 9.8 1.7e-74 250.9 9.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EIM87006.1 - 3.7e-19 68.3 0.2 2.2e-18 65.8 0.2 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p Prokineticin PF06607.11 EIM87006.1 - 0.35 11.2 1.3 14 6.1 0.4 3.2 3 1 1 4 4 4 0 Prokineticin DUF805 PF05656.14 EIM87006.1 - 2.8 8.4 7.3 0.54 10.7 0.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF805) PH PF00169.29 EIM87007.1 - 0.0017 18.8 0.0 0.0017 18.8 0.0 2.2 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 EIM87007.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.32 EIM87009.1 - 2.3e-10 40.9 14.8 8.2e-06 26.5 0.0 5.1 4 1 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_60s PF00428.19 EIM87010.1 - 8.9e-28 96.7 9.9 1.3e-27 96.1 9.9 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Amidase PF01425.21 EIM87011.1 - 2.7e-74 250.8 0.2 3.4e-74 250.4 0.2 1.1 1 0 0 1 1 1 1 Amidase HTH_15 PF12324.8 EIM87011.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase FAD_binding_4 PF01565.23 EIM87013.1 - 9.6e-28 96.7 2.7 1.4e-27 96.1 2.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM87013.1 - 3.7e-12 46.1 1.0 6.3e-12 45.4 1.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EIM87014.1 - 5.5e-27 94.2 0.8 8.1e-27 93.7 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM87014.1 - 1.9e-16 59.9 0.6 3.3e-16 59.1 0.6 1.4 1 0 0 1 1 1 1 Berberine and berberine like zf-MYND PF01753.18 EIM87016.1 - 9.3e-10 38.4 12.4 2.1e-09 37.3 12.4 1.6 1 0 0 1 1 1 1 MYND finger FAD_binding_4 PF01565.23 EIM87017.1 - 9.7e-25 86.9 1.1 1.5e-24 86.4 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM87017.1 - 4.3e-12 45.9 0.3 8.2e-12 45.0 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 EIM87018.1 - 6.4e-27 94.4 39.1 6.4e-27 94.4 39.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 EIM87018.1 - 0.41 11.1 3.1 0.47 10.9 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 MFS_1 PF07690.16 EIM87019.1 - 5e-20 71.7 36.6 5e-20 71.7 36.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MaoC_dehydratas PF01575.19 EIM87020.1 - 1.9e-27 95.3 0.0 7.9e-27 93.3 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EIM87020.1 - 4.6e-06 26.8 0.0 0.0082 16.3 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Peptidase_C28 PF05408.11 EIM87020.1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Hexokinase_2 PF03727.16 EIM87021.1 - 4.6e-82 275.1 0.1 6.1e-82 274.6 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EIM87021.1 - 9.2e-65 218.3 0.0 1.3e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase YscK PF06578.12 EIM87021.1 - 0.048 13.2 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Ribosomal_L14 PF00238.19 EIM87022.1 - 2.7e-44 150.2 1.0 3e-44 150.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DNA_ligase_aden PF01653.18 EIM87022.1 - 0.095 11.8 0.3 0.14 11.2 0.1 1.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase adenylation domain MFS_1 PF07690.16 EIM87023.1 - 1.3e-54 185.4 18.8 1.8e-54 185.0 18.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EIM87023.1 - 1.3e-09 36.9 0.3 2.3e-07 29.5 0.1 3.0 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EIM87023.1 - 9.3e-08 31.4 16.6 2.2e-07 30.1 0.6 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EIM87023.1 - 0.00017 20.6 12.6 0.00044 19.2 1.3 3.1 3 0 0 3 3 3 2 MFS_1 like family EptA_B_N PF08019.12 EIM87023.1 - 0.024 14.5 6.5 2.4 8.0 0.1 3.5 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB DUF2512 PF10710.9 EIM87023.1 - 1.4 8.6 5.3 0.63 9.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) AMP-binding PF00501.28 EIM87025.1 - 8.6e-69 232.1 0.0 1.1e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM87025.1 - 3e-14 53.7 0.1 7.4e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 EIM87026.1 - 1.1e-51 175.8 0.2 2.2e-51 174.9 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EIM87026.1 - 2.3e-42 145.6 0.0 3.6e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EIM87026.1 - 5.2e-32 111.2 0.0 1.2e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EIM87026.1 - 2.8e-26 92.5 0.0 8.3e-26 90.9 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EIM87026.1 - 2.9e-26 91.8 0.1 5.9e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EIM87026.1 - 1.9e-17 63.8 0.0 3.9e-13 50.0 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EIM87026.1 - 5.4e-15 55.6 0.0 1e-10 41.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Thioesterase PF00975.20 EIM87026.1 - 7.8e-12 45.8 0.0 2.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 EIM87026.1 - 2e-09 37.9 0.0 4.9e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 EIM87026.1 - 8.8e-08 32.7 0.0 0.00016 22.3 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EIM87026.1 - 2.4e-06 27.4 0.0 0.00059 19.7 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM87026.1 - 5e-06 27.1 0.0 0.0023 18.6 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain ACP_syn_III PF08545.10 EIM87026.1 - 0.00015 21.5 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EIM87026.1 - 0.00018 21.0 0.1 0.00037 20.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EIM87026.1 - 0.008 15.5 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EIM87026.1 - 0.041 14.2 0.3 0.12 12.8 0.3 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site DREV PF05219.12 EIM87026.1 - 0.18 10.9 0.0 1.7 7.7 0.0 2.3 2 1 0 2 2 2 0 DREV methyltransferase Sod_Fe_C PF02777.18 EIM87027.1 - 4e-33 113.6 0.0 7.9e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EIM87027.1 - 6e-31 106.8 3.5 7e-31 106.5 1.5 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ocnus PF05005.15 EIM87027.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) RTA1 PF04479.13 EIM87028.1 - 1.7e-63 214.0 5.2 1.7e-63 214.0 5.2 1.4 2 0 0 2 2 2 1 RTA1 like protein F-box-like PF12937.7 EIM87030.1 - 0.087 12.7 4.7 0.61 10.0 2.7 2.9 2 1 0 2 2 2 0 F-box-like NicO PF03824.16 EIM87031.1 - 3.9 6.7 4.7 0.71 9.2 0.1 1.8 2 0 0 2 2 2 0 High-affinity nickel-transport protein MULE PF10551.9 EIM87032.1 - 2.4e-10 40.7 0.0 9.7e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EIM87032.1 - 5.9e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger DUF1390 PF07150.11 EIM87032.1 - 0.23 11.2 0.5 0.45 10.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) ODV-E18 PF10717.9 EIM87034.1 - 0.021 14.7 2.6 0.33 10.8 0.9 2.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF2628 PF10947.8 EIM87034.1 - 5.8 7.3 7.4 0.72 10.2 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Peptidase_C14 PF00656.22 EIM87035.1 - 1.1e-17 64.8 0.2 1.5e-17 64.4 0.2 1.0 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM87035.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.2 1 1 0 1 1 1 1 CHAT domain F-box-like PF12937.7 EIM87036.1 - 1.4e-10 40.9 1.1 4.2e-05 23.4 0.3 2.9 2 0 0 2 2 2 2 F-box-like F-box_5 PF18511.1 EIM87036.1 - 0.033 13.8 6.2 0.09 12.4 0.2 3.3 3 0 0 3 3 3 0 F-box Glyco_hydro_92 PF07971.12 EIM87038.1 - 3e-123 412.2 0.0 3.6e-123 411.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EIM87038.1 - 7.8e-51 173.3 1.0 1.2e-50 172.7 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain MCU PF04678.13 EIM87039.1 - 9.3e-37 126.8 0.0 1.6e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial calcium uniporter LRR_8 PF13855.6 EIM87040.1 - 3.2e-50 167.7 59.8 8.2e-14 51.1 0.7 10.4 5 3 6 12 12 12 10 Leucine rich repeat PP2C PF00481.21 EIM87040.1 - 1.3e-40 139.6 0.0 2.6e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 EIM87040.1 - 3.9e-36 122.5 52.9 1.5e-06 28.4 0.5 12.7 8 3 4 14 14 14 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EIM87040.1 - 5.2e-18 65.3 0.0 9.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EIM87040.1 - 2.4e-06 27.1 23.7 0.001 18.6 0.5 6.0 1 1 3 6 6 6 4 Leucine-rich repeat LRR_1 PF00560.33 EIM87040.1 - 0.00024 21.2 49.3 6.9 7.6 0.1 14.0 15 2 0 15 15 15 3 Leucine Rich Repeat LRR_5 PF13306.6 EIM87040.1 - 0.00038 20.4 0.1 12 5.9 0.0 4.0 2 1 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) Med26 PF08711.11 EIM87042.1 - 1.3e-06 28.3 0.1 6.8e-06 26.0 0.0 2.2 3 0 0 3 3 3 1 TFIIS helical bundle-like domain FAM184 PF15665.5 EIM87042.1 - 0.011 15.6 0.5 0.018 14.9 0.5 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Sds3 PF08598.11 EIM87042.1 - 0.031 14.3 0.5 0.046 13.7 0.5 1.2 1 0 0 1 1 1 0 Sds3-like Mitofilin PF09731.9 EIM87042.1 - 0.16 10.8 2.6 0.24 10.2 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nbl1_Borealin_N PF10444.9 EIM87042.1 - 0.6 9.8 4.9 0.83 9.3 3.2 2.0 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal Glyco_hydro_5_C PF18564.1 EIM87043.1 - 2.1e-21 76.2 0.0 4e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EIM87043.1 - 2.3e-12 46.9 0.0 2.1e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) SesA PF17107.5 EIM87044.1 - 6.7e-06 26.3 1.5 1.7e-05 25.0 0.1 2.0 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec34 PF04136.15 EIM87044.1 - 0.077 12.9 3.4 1.9 8.3 0.2 2.5 2 1 0 2 2 2 0 Sec34-like family Y_phosphatase3 PF13350.6 EIM87045.1 - 1.5e-07 31.6 0.0 2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EIM87045.1 - 1.8e-07 31.0 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EIM87045.1 - 4.7e-06 26.4 0.0 7.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EIM87045.1 - 6.8e-06 25.8 0.0 9.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EIM87045.1 - 0.00024 21.3 0.0 0.00072 19.7 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate MFS_1 PF07690.16 EIM87047.1 - 4.6e-30 104.8 43.5 7.4e-30 104.1 43.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GWT1 PF06423.12 EIM87048.1 - 1e-37 129.6 0.1 5.4e-36 124.0 0.1 3.1 2 1 0 2 2 2 1 GWT1 APH PF01636.23 EIM87050.1 - 1.3e-14 54.7 0.0 3.8e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EIM87050.1 - 0.0014 18.3 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EIM87050.1 - 0.0028 17.3 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EIM87050.1 - 0.0052 15.7 0.0 0.011 14.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 EIM87050.1 - 0.015 14.6 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Fructosamin_kin PF03881.14 EIM87050.1 - 0.079 12.1 0.0 0.34 10.1 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase Pkinase PF00069.25 EIM87054.1 - 1.3e-63 214.9 0.0 2.7e-63 213.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87054.1 - 1e-43 149.5 0.0 2.7e-43 148.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.8 EIM87054.1 - 8.8e-36 123.6 0.5 1.8e-35 122.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 EIM87054.1 - 0.0095 15.9 0.0 0.045 13.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM87054.1 - 0.11 11.3 0.0 0.27 10.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EIM87054.1 - 0.21 10.9 0.0 28 3.9 0.0 2.6 2 1 0 2 2 2 0 Kinase-like DUF2709 PF10915.8 EIM87054.1 - 0.22 10.8 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) NUDE_C PF04880.13 EIM87054.1 - 0.3 11.5 2.9 0.81 10.1 2.9 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region GpcrRhopsn4 PF10192.9 EIM87055.1 - 0.0088 15.5 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain YbgS PF13985.6 EIM87056.1 - 0.037 14.3 2.3 0.055 13.8 2.3 1.3 1 0 0 1 1 1 0 YbgS-like protein Kelch_3 PF13415.6 EIM87058.1 - 0.92 9.9 3.8 6 7.3 1.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain F-box-like PF12937.7 EIM87059.1 - 9.6e-10 38.2 0.9 3.1e-09 36.6 0.9 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM87060.1 - 8.1e-10 38.5 0.5 8.1e-10 38.5 0.5 2.7 3 0 0 3 3 3 1 F-box-like SDA1 PF05285.12 EIM87061.1 - 2.8 7.3 18.2 5.4 6.3 4.1 2.4 2 0 0 2 2 2 0 SDA1 Ribosomal_L28 PF00830.19 EIM87062.1 - 6.6e-20 71.1 0.4 1.2e-19 70.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Orthopox_A43R PF06517.11 EIM87062.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A43R protein F-box-like PF12937.7 EIM87065.1 - 1.6e-06 27.9 5.3 1.1e-05 25.3 5.3 2.6 1 1 0 1 1 1 1 F-box-like RNA_Me_trans PF04252.13 EIM87066.1 - 3.2e-68 229.3 0.0 7.5e-68 228.0 0.0 1.6 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Ninjurin PF04923.12 EIM87067.1 - 0.52 10.3 3.4 2.2 8.3 0.2 2.7 3 0 0 3 3 3 0 Ninjurin DUF3176 PF11374.8 EIM87067.1 - 0.98 9.6 9.1 0.52 10.6 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3176) MscL PF01741.18 EIM87068.1 - 2.3e-17 63.4 0.9 2.8e-17 63.1 0.9 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Alpha-L-AF_C PF06964.12 EIM87070.1 - 1.6e-33 116.2 0.3 4.4e-33 114.8 0.1 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 EIM87070.1 - 0.019 15.2 0.3 0.057 13.7 0.3 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain TIMELESS PF04821.14 EIM87071.1 - 1.3e-83 280.5 0.8 4.2e-83 278.8 0.8 2.0 1 0 0 1 1 1 1 Timeless protein bZIP_1 PF00170.21 EIM87072.1 - 2.4e-05 24.3 8.8 0.0013 18.8 2.1 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 EIM87072.1 - 9.3e-05 22.4 11.9 0.00072 19.6 1.1 2.4 2 0 0 2 2 2 2 Basic region leucine zipper CSTF_C PF14304.6 EIM87072.1 - 0.013 15.1 1.6 0.013 15.1 1.6 2.0 2 1 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Shugoshin_N PF07558.11 EIM87072.1 - 0.038 13.8 5.0 0.038 13.8 5.0 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GOLGA2L5 PF15070.6 EIM87072.1 - 0.048 12.3 3.6 0.068 11.8 3.6 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 YabA PF06156.13 EIM87072.1 - 0.097 13.3 0.3 0.19 12.4 0.3 1.5 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_Maf PF03131.17 EIM87072.1 - 0.43 11.1 8.1 5.2 7.7 1.0 3.2 3 0 0 3 3 3 0 bZIP Maf transcription factor DivIC PF04977.15 EIM87072.1 - 7.4 6.4 6.2 13 5.7 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 EIM87072.1 - 9.3 6.4 11.0 6.2 7.0 5.3 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain TAL_FSA PF00923.19 EIM87073.1 - 4.8e-17 62.2 0.0 7.8e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Hydrolase_6 PF13344.6 EIM87074.1 - 2e-32 111.3 0.0 3.9e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM87074.1 - 5e-21 74.5 0.0 1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EIM87074.1 - 1.3e-10 41.9 0.0 2.5e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EIM87074.1 - 1.9e-10 41.1 0.0 7.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EIM87074.1 - 0.0041 16.8 0.0 0.12 12.0 0.0 2.6 3 0 0 3 3 3 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 EIM87074.1 - 0.077 12.6 0.2 0.22 11.1 0.2 1.6 1 1 1 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peripla_BP_4 PF13407.6 EIM87074.1 - 0.19 11.2 0.0 0.8 9.2 0.0 1.8 1 1 1 2 2 2 0 Periplasmic binding protein domain Polysacc_synt_4 PF04669.13 EIM87076.1 - 1.2e-19 70.7 1.8 4.5e-18 65.5 1.8 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis PP_kinase PF02503.17 EIM87076.1 - 0.0045 16.6 0.7 0.0051 16.4 0.7 1.2 1 0 0 1 1 1 1 Polyphosphate kinase middle domain zf-MYND PF01753.18 EIM87078.1 - 2e-06 27.8 10.2 2e-06 27.8 10.2 3.0 3 0 0 3 3 3 1 MYND finger DUF4905 PF16248.5 EIM87078.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) p450 PF00067.22 EIM87079.1 - 1.4e-70 238.3 0.0 3.5e-70 237.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EIM87080.1 - 2.3e-06 27.4 1.1 5.9e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like p450 PF00067.22 EIM87080.1 - 1.7e-05 23.8 0.0 0.019 13.7 0.0 3.6 1 1 3 4 4 4 2 Cytochrome P450 F-box PF00646.33 EIM87080.1 - 4.4e-05 23.3 0.9 0.00018 21.3 0.9 2.2 1 0 0 1 1 1 1 F-box domain Fibrillarin PF01269.17 EIM87080.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Aminotran_1_2 PF00155.21 EIM87081.1 - 4e-36 125.0 0.0 6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIM87081.1 - 0.11 11.0 0.0 0.24 9.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF677 PF05055.12 EIM87082.1 - 0.03 13.2 0.4 0.053 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) FAM27 PF15832.5 EIM87082.1 - 0.21 12.2 0.2 0.21 12.2 0.2 2.6 2 0 0 2 2 2 0 FAM27 D and E protein family SlyX PF04102.12 EIM87082.1 - 0.42 11.3 3.3 11 6.7 0.0 3.6 2 1 1 3 3 3 0 SlyX p450 PF00067.22 EIM87083.1 - 1.3e-69 235.2 0.0 4.2e-69 233.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.31 EIM87084.1 - 4e-09 36.5 0.3 6.9e-09 35.8 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIM87084.1 - 6.7e-05 23.1 0.3 0.00015 21.9 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.9 EIM87084.1 - 0.00019 21.1 3.0 0.00019 21.1 3.0 2.6 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 EIM87084.1 - 0.012 15.3 13.7 0.014 15.2 5.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BNIP2 PF12496.8 EIM87084.1 - 0.85 10.1 8.5 3.6 8.0 0.1 2.7 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 T2SSM PF04612.12 EIM87084.1 - 1.7 8.7 5.2 0.76 9.8 0.5 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4598 PF15370.6 EIM87084.1 - 3.2 8.2 12.5 0.96 10.0 4.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) PIG-F PF06699.11 EIM87085.1 - 4.7e-28 98.6 0.9 4.2e-15 56.4 0.3 2.2 2 0 0 2 2 2 2 GPI biosynthesis protein family Pig-F Ribosomal_L34e PF01199.18 EIM87086.1 - 1.2e-43 147.3 4.7 1.8e-43 146.8 4.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.6 EIM87086.1 - 0.1 13.1 2.0 0.23 12.0 2.0 1.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain NACHT PF05729.12 EIM87087.1 - 8.8e-09 35.5 0.0 2.3e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EIM87087.1 - 2.1e-05 25.0 0.1 2.1e-05 25.0 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 EIM87087.1 - 0.00018 20.8 0.0 0.00035 19.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Ribosomal_L34e PF01199.18 EIM87088.1 - 4.4e-16 59.0 0.6 1.9e-07 31.3 0.1 2.3 1 1 1 2 2 2 2 Ribosomal protein L34e TPR_10 PF13374.6 EIM87089.1 - 3.7e-82 268.2 71.6 3.5e-08 33.1 0.8 19.1 19 0 0 19 19 18 17 Tetratricopeptide repeat TPR_12 PF13424.6 EIM87089.1 - 3.2e-47 158.7 54.5 6.5e-06 26.3 0.1 16.6 7 4 9 16 16 16 14 Tetratricopeptide repeat ANAPC5 PF12862.7 EIM87089.1 - 1e-28 99.2 44.9 0.016 15.3 0.1 17.6 5 4 14 19 19 18 8 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 EIM87089.1 - 2.6e-24 83.3 23.3 0.62 10.3 0.1 17.5 19 0 0 19 19 18 5 Tetratricopeptide repeat DUF3856 PF12968.7 EIM87089.1 - 2.2e-11 44.0 23.7 0.0015 18.6 0.7 7.7 4 1 4 9 9 9 5 Domain of Unknown Function (DUF3856) NACHT PF05729.12 EIM87089.1 - 4.3e-09 36.5 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 EIM87089.1 - 7.5e-08 32.0 8.3 39 4.8 0.0 11.8 15 0 0 15 15 12 0 Tetratricopeptide repeat AAA_16 PF13191.6 EIM87089.1 - 1e-06 29.3 0.0 1e-06 29.3 0.0 4.5 4 1 1 5 5 4 1 AAA ATPase domain TPR_6 PF13174.6 EIM87089.1 - 2.9e-05 24.4 14.8 16 6.4 0.1 9.7 10 0 0 10 10 7 0 Tetratricopeptide repeat Sec16_C PF12931.7 EIM87089.1 - 7.5e-05 22.5 11.1 11 5.5 0.0 7.2 5 1 0 8 8 8 0 Sec23-binding domain of Sec16 AAA_18 PF13238.6 EIM87089.1 - 0.0013 19.3 0.0 2.1 8.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM87089.1 - 0.0016 18.7 0.0 0.02 15.2 0.0 2.9 3 0 0 3 3 1 1 AAA domain CCAP PF11105.8 EIM87089.1 - 0.0018 18.2 0.1 3.6 7.6 0.1 4.0 2 1 1 3 3 3 1 Arthropod cardioacceleratory peptide 2a Telomere_reg-2 PF10193.9 EIM87089.1 - 0.027 14.9 12.0 2.8 8.4 0.3 5.5 4 1 0 5 5 5 0 Telomere length regulation protein Pro-NT_NN PF07421.11 EIM87089.1 - 0.037 14.3 13.0 26 5.0 0.8 6.5 2 1 7 10 10 10 0 Neurotensin/neuromedin N precursor DUF4003 PF13170.6 EIM87089.1 - 0.06 12.7 3.3 3.4 6.9 0.1 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4003) Zeta_toxin PF06414.12 EIM87089.1 - 0.099 11.9 0.0 0.33 10.2 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin CagY_M PF07337.11 EIM87089.1 - 0.12 12.0 0.2 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 DC-EC Repeat AAA PF00004.29 EIM87089.1 - 0.12 12.8 0.0 0.4 11.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_1 PF00515.28 EIM87089.1 - 0.13 12.1 9.6 6.2 6.8 0.0 7.0 9 0 0 9 9 5 0 Tetratricopeptide repeat SNAP PF14938.6 EIM87089.1 - 0.4 10.0 20.1 0.11 12.0 0.6 5.3 3 2 1 5 5 5 0 Soluble NSF attachment protein, SNAP DUF4921 PF16268.5 EIM87089.1 - 0.91 8.3 3.6 3 6.6 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4921) WSD PF15613.6 EIM87089.1 - 1.2 9.7 11.5 81 3.8 0.0 6.4 6 2 0 6 6 6 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif FAT PF02259.23 EIM87089.1 - 2.4 7.3 7.4 11 5.2 0.3 4.0 3 1 0 4 4 4 0 FAT domain DUF4404 PF14357.6 EIM87089.1 - 5.1 7.8 10.8 30 5.3 0.0 6.1 5 1 0 6 6 5 0 Domain of unknown function (DUF4404) DUF630 PF04783.12 EIM87089.1 - 7.9 6.7 16.0 1.4 9.2 0.2 6.4 6 1 0 6 6 4 0 Protein of unknown function (DUF630) RCR PF12273.8 EIM87091.1 - 0.018 15.7 3.7 0.042 14.5 3.7 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4272 PF14094.6 EIM87091.1 - 0.045 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) F-box-like PF12937.7 EIM87092.1 - 1.5e-07 31.2 1.5 6.8e-07 29.1 1.5 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM87093.1 - 2.4e-09 37.0 0.1 6.8e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF4072 PF13284.6 EIM87093.1 - 0.093 13.2 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) F-box-like PF12937.7 EIM87094.1 - 4.8e-08 32.8 0.9 2.6e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EIM87095.1 - 2.3e-06 27.4 1.9 6.5e-06 25.9 1.9 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM87095.1 - 0.028 14.8 2.6 14 6.3 0.2 4.3 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM87095.1 - 1.2 9.0 3.2 39 4.1 0.3 3.6 3 1 0 3 3 3 0 Leucine rich repeat Cohesin_load PF10345.9 EIM87097.1 - 0.00027 19.6 0.1 0.16 10.3 0.0 2.5 3 0 0 3 3 3 2 Cohesin loading factor F-box-like PF12937.7 EIM87099.1 - 4.3e-07 29.7 0.4 1.2e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like DUF3561 PF12084.8 EIM87099.1 - 0.45 10.5 3.0 8 6.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) F-box-like PF12937.7 EIM87100.1 - 0.00042 20.1 1.8 0.00059 19.7 0.4 2.1 2 0 0 2 2 2 1 F-box-like DUF4883 PF16224.5 EIM87100.1 - 0.031 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) CAP59_mtransfer PF11735.8 EIM87102.1 - 9.1e-69 231.8 0.0 1.2e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 APH PF01636.23 EIM87104.1 - 2.2e-14 53.9 0.1 2.8e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM87104.1 - 0.0039 16.8 0.1 0.039 13.6 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EIM87104.1 - 0.012 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EIM87104.1 - 0.023 14.0 0.0 0.026 13.8 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1289 PF06945.13 EIM87104.1 - 0.16 11.8 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Beta_helix PF13229.6 EIM87106.1 - 4.3e-07 29.9 5.8 4.4e-06 26.6 4.9 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EIM87106.1 - 0.0055 16.0 0.3 0.0083 15.4 0.3 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Nop53 PF07767.11 EIM87107.1 - 1.2e-92 311.4 24.8 1.4e-92 311.1 24.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.12 EIM87107.1 - 0.00073 19.5 2.5 0.00073 19.5 2.5 2.4 2 1 0 2 2 2 1 BOP1NT (NUC169) domain F-box-like PF12937.7 EIM87110.1 - 3.3e-08 33.3 4.5 4.2e-08 33.0 2.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM87110.1 - 0.22 11.4 7.0 18 5.4 4.2 3.5 2 1 0 2 2 2 0 F-box domain CFEM PF05730.11 EIM87111.1 - 4.1e-12 46.0 11.6 9.9e-12 44.8 11.6 1.6 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.11 EIM87111.1 - 0.0085 16.5 15.2 0.011 16.2 15.2 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Apt1 PF10351.9 EIM87111.1 - 0.65 8.8 3.9 0.8 8.5 3.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 EIM87111.1 - 1.3 7.2 18.2 1.4 7.1 18.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 EIM87111.1 - 6 5.3 9.4 6.9 5.1 9.4 1.1 1 0 0 1 1 1 0 Macoilin family Sporozoite_P67 PF05642.11 EIM87111.1 - 8 4.4 14.2 8.7 4.3 14.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L31e PF01198.19 EIM87112.1 - 1.5e-39 134.1 1.9 1.8e-39 133.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EIM87112.1 - 0.082 13.0 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein F-box-like PF12937.7 EIM87113.1 - 0.00015 21.6 0.6 0.00015 21.6 0.6 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EIM87113.1 - 0.027 14.9 3.4 13 6.3 0.1 4.1 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) RPN7 PF10602.9 EIM87116.1 - 6.3e-38 130.2 0.1 9.8e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EIM87116.1 - 1.7e-15 57.4 0.2 7.9e-15 55.3 0.0 2.2 2 1 0 2 2 2 1 PCI domain CENP-F_N PF10481.9 EIM87116.1 - 0.0027 17.4 1.6 0.003 17.3 0.1 1.7 2 0 0 2 2 2 1 Cenp-F N-terminal domain TPR_2 PF07719.17 EIM87116.1 - 0.023 14.8 0.2 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM87116.1 - 0.19 12.0 5.3 0.89 9.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.22 EIM87117.1 - 1.1e-45 156.2 0.0 1.5e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 EIM87118.1 - 5.1e-55 186.9 0.0 7.3e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87118.1 - 6.4e-31 107.8 0.0 1.4e-30 106.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM87118.1 - 6.5e-05 22.2 0.0 9.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EIM87118.1 - 0.004 16.8 3.8 0.03 13.9 3.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM87118.1 - 0.0058 15.9 0.2 0.02 14.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EIM87118.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EIM87118.1 - 0.15 10.9 0.2 0.22 10.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Usp PF00582.26 EIM87119.1 - 4.9e-15 56.3 0.1 7.3e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family WW PF00397.26 EIM87120.1 - 3.6e-09 36.6 3.8 8.9e-09 35.3 3.8 1.7 1 0 0 1 1 1 1 WW domain R2K_2 PF18299.1 EIM87121.1 - 0.081 12.8 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 GMC_oxred_N PF00732.19 EIM87122.1 - 4.8e-56 190.3 0.0 7.2e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87122.1 - 6.6e-34 117.5 0.0 1.3e-33 116.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase F-box-like PF12937.7 EIM87123.1 - 1.5e-06 28.0 2.1 4.1e-06 26.6 2.1 1.7 1 0 0 1 1 1 1 F-box-like FHA PF00498.26 EIM87124.1 - 2.2e-06 27.9 0.0 4.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EIM87124.1 - 0.026 14.8 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Asp PF00026.23 EIM87125.1 - 2.7e-41 142.0 11.2 1.2e-40 139.9 11.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM87125.1 - 1.4e-06 28.6 3.0 0.043 14.0 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal p450 PF00067.22 EIM87127.1 - 1.5e-52 179.0 0.0 1.4e-51 175.7 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM87128.1 - 1.1e-67 228.8 0.0 4.2e-67 226.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM87129.1 - 3.2e-69 233.9 0.0 1.5e-68 231.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM87130.1 - 8.5e-68 229.2 0.0 2.8e-67 227.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF4470 PF14737.6 EIM87131.1 - 2.4e-09 37.3 0.0 6e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EIM87131.1 - 0.00011 22.0 2.1 0.0026 17.7 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM87131.1 - 0.0021 18.7 0.8 0.0053 17.4 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM87131.1 - 0.0072 16.0 0.7 0.014 15.1 0.7 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EIM87131.1 - 0.047 13.5 0.1 0.047 13.5 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat O-FucT PF10250.9 EIM87132.1 - 8e-11 42.2 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4245 PF14030.6 EIM87132.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Asp PF00026.23 EIM87134.1 - 2.6e-51 174.9 20.8 5.4e-51 173.9 20.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM87134.1 - 8.6e-10 39.1 7.1 1.8e-05 25.1 0.4 3.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM87134.1 - 0.022 15.4 2.0 0.022 15.4 2.0 3.6 4 0 0 4 4 4 0 Aspartyl protease gag-asp_proteas PF13975.6 EIM87134.1 - 3 8.5 7.3 0.45 11.1 0.4 2.9 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease DUF3328 PF11807.8 EIM87135.1 - 4.2e-20 72.5 3.2 9.5e-20 71.3 3.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Asp PF00026.23 EIM87136.1 - 1.8e-51 175.5 12.9 6e-51 173.7 12.9 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM87136.1 - 1.6e-09 38.2 5.2 5.1e-06 26.8 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Atu4866 PF11512.8 EIM87136.1 - 0.088 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 DUF4470 PF14737.6 EIM87137.1 - 1.2e-06 28.6 0.0 2.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EIM87137.1 - 1.1e-05 25.0 0.1 2.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EIM87137.1 - 8.9e-05 22.3 2.1 0.0019 18.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM87137.1 - 0.00065 19.4 1.4 0.00095 18.9 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat CbbQ_C PF08406.10 EIM87137.1 - 0.032 14.5 0.2 0.065 13.5 0.2 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal DUF309 PF03745.14 EIM87137.1 - 0.074 12.7 0.1 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF309) p450 PF00067.22 EIM87138.1 - 1.2e-58 199.0 0.0 3.1e-58 197.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EIM87140.1 - 4.7e-07 29.6 0.2 4.7e-07 29.6 0.2 1.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM87142.1 - 0.0081 16.6 2.5 0.34 11.4 0.4 3.4 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) Peptidase_M48_N PF16491.5 EIM87143.1 - 1.2e-59 201.3 7.8 2.1e-59 200.5 7.8 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EIM87143.1 - 4.8e-34 117.9 0.0 6.2e-25 88.1 0.0 2.8 2 1 0 2 2 2 2 Peptidase family M48 Peptidase_M56 PF05569.11 EIM87143.1 - 0.054 12.7 0.1 0.086 12.0 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Molybdopterin PF00384.22 EIM87144.1 - 6.9e-67 226.3 0.0 9.1e-66 222.6 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 EIM87144.1 - 1.5e-17 62.8 0.2 1.5e-17 62.8 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 EIM87144.1 - 3e-16 59.8 0.0 6.8e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 EIM87144.1 - 3.7e-12 46.1 0.2 1e-11 44.7 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 EIM87144.1 - 1e-05 25.4 0.6 1e-05 25.4 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EIM87144.1 - 0.038 13.7 0.0 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Chorismate_bind PF00425.18 EIM87145.1 - 0.25 10.9 0.4 0.46 10.0 0.4 1.3 1 0 0 1 1 1 0 chorismate binding enzyme p450 PF00067.22 EIM87146.1 - 5.8e-59 200.1 0.0 8.7e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 EMC3_TMCO1 PF01956.16 EIM87146.1 - 0.6 9.8 2.1 3.4 7.4 0.5 2.2 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Surp PF01805.20 EIM87147.1 - 0.08 13.0 0.1 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Surp module DRY_EERY PF09750.9 EIM87147.1 - 0.1 12.9 0.0 0.1 12.9 0.0 2.5 3 1 0 3 3 3 0 Alternative splicing regulator BTB PF00651.31 EIM87149.1 - 1.8e-14 53.9 0.1 2.7e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain HATPase_c_3 PF13589.6 EIM87149.1 - 0.005 16.7 0.2 4.2 7.2 0.1 3.2 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC2_membrane PF01061.24 EIM87152.1 - 4.6e-77 258.2 50.1 2e-44 151.6 19.7 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EIM87152.1 - 1.7e-36 125.7 0.0 7.6e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EIM87152.1 - 3.9e-34 116.4 8.6 3e-28 97.5 0.9 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EIM87152.1 - 2.5e-14 53.6 0.0 5.9e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EIM87152.1 - 2.2e-08 34.7 0.1 0.00036 20.9 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM87152.1 - 7e-07 29.3 0.1 5.8e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EIM87152.1 - 2.5e-06 27.8 0.1 0.047 14.0 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EIM87152.1 - 6.5e-06 25.8 0.0 0.014 14.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EIM87152.1 - 8.7e-05 22.8 0.1 0.69 10.1 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EIM87152.1 - 0.00044 19.9 0.5 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 EIM87152.1 - 0.00045 20.2 0.1 0.41 10.6 0.2 2.8 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 EIM87152.1 - 0.00073 19.4 0.1 0.29 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EIM87152.1 - 0.0008 20.0 0.0 1.8 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EIM87152.1 - 0.00088 19.3 0.2 0.69 10.0 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 EIM87152.1 - 0.0023 17.6 1.2 0.62 9.6 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EIM87152.1 - 0.0034 17.5 0.1 0.76 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM87152.1 - 0.028 14.2 0.1 0.87 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EIM87152.1 - 0.028 14.2 0.2 3.2 7.5 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 EIM87152.1 - 0.042 13.3 0.0 1.1 8.7 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EIM87152.1 - 0.043 14.0 0.0 10 6.4 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 EIM87152.1 - 0.043 13.1 0.0 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Septin Rad17 PF03215.15 EIM87152.1 - 0.065 13.1 0.0 20 5.0 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain dNK PF01712.19 EIM87152.1 - 0.079 12.8 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 EIM87152.1 - 0.096 12.0 0.1 3.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EIM87152.1 - 0.14 12.6 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EIM87152.1 - 0.15 12.6 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EIM87152.1 - 0.19 12.0 0.0 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EIM87152.1 - 0.21 11.9 0.2 13 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EIM87152.1 - 0.23 11.5 0.5 0.86 9.6 0.2 2.1 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC2_membrane_3 PF12698.7 EIM87152.1 - 1.8 7.6 52.1 5 6.1 31.5 3.4 2 1 0 2 2 2 0 ABC-2 family transporter protein Chitin_synth_2 PF03142.15 EIM87153.1 - 1.7e-234 779.3 0.1 2.5e-234 778.8 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EIM87153.1 - 1.1e-141 473.3 0.0 3.6e-141 471.7 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EIM87153.1 - 3.5e-19 68.4 0.7 2e-18 66.0 1.4 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EIM87153.1 - 2.2e-10 40.6 0.1 0.00012 22.2 0.0 2.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EIM87153.1 - 9.8e-10 38.7 5.6 1.2e-09 38.4 3.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIM87153.1 - 4.8e-09 36.4 0.0 5.7e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIM87153.1 - 4.3e-05 23.4 0.0 0.091 12.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 EIM87153.1 - 0.061 13.6 0.3 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SURF6 PF04935.12 EIM87154.1 - 1.7e-47 161.8 48.6 1.7e-47 161.8 48.6 3.0 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EIM87154.1 - 1.1e-19 70.8 5.1 1.1e-19 70.8 5.1 6.0 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 ABC_membrane PF00664.23 EIM87155.1 - 1.6e-73 247.7 26.0 6.7e-37 127.6 2.9 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM87155.1 - 9.5e-64 214.0 0.0 1.1e-31 110.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM87155.1 - 2.9e-14 53.1 2.5 3.6e-05 23.3 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EIM87155.1 - 4e-07 29.9 0.1 0.87 9.3 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC_ATPase PF09818.9 EIM87155.1 - 5.8e-07 28.7 5.2 0.00015 20.7 0.1 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EIM87155.1 - 8.6e-07 28.6 5.8 0.014 15.1 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EIM87155.1 - 1e-06 28.8 0.2 6.9 6.4 0.0 4.2 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EIM87155.1 - 1.3e-06 28.7 0.4 0.1 12.9 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIM87155.1 - 1.3e-06 28.9 1.6 0.024 15.0 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM87155.1 - 4.2e-06 26.8 0.1 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EIM87155.1 - 8.5e-06 25.6 0.9 0.057 13.1 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EIM87155.1 - 2.4e-05 24.2 0.0 0.077 12.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EIM87155.1 - 4.9e-05 22.7 0.1 0.25 10.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 EIM87155.1 - 9e-05 23.0 0.0 0.18 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EIM87155.1 - 0.00015 22.0 0.1 0.029 14.4 0.0 2.6 3 0 0 3 3 2 1 Helicase HerA, central domain APS_kinase PF01583.20 EIM87155.1 - 0.0007 19.5 0.2 1 9.2 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_25 PF13481.6 EIM87155.1 - 0.001 18.7 1.6 1.5 8.4 0.2 3.8 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EIM87155.1 - 0.0014 19.0 0.2 0.59 10.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase G-alpha PF00503.20 EIM87155.1 - 0.0025 17.1 0.3 0.2 10.8 0.0 2.5 3 0 0 3 3 2 1 G-protein alpha subunit AAA_33 PF13671.6 EIM87155.1 - 0.0028 17.8 0.1 4.1 7.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EIM87155.1 - 0.004 17.2 0.0 6.2 6.8 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EIM87155.1 - 0.0094 16.2 2.8 4.1 7.7 0.5 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CbiA PF01656.23 EIM87155.1 - 0.011 15.8 0.2 1.9 8.6 0.0 2.8 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EIM87155.1 - 0.012 15.3 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EIM87155.1 - 0.013 15.1 0.0 6 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EIM87155.1 - 0.021 14.5 0.0 5.2 6.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 EIM87155.1 - 0.025 14.3 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 EIM87155.1 - 0.028 14.1 0.0 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 EIM87155.1 - 0.029 13.5 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EIM87155.1 - 0.032 13.6 0.2 9 5.6 0.1 2.5 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EIM87155.1 - 0.032 14.2 0.2 8.5 6.3 0.0 3.3 3 0 0 3 3 3 0 NACHT domain DUF3987 PF13148.6 EIM87155.1 - 0.046 12.7 0.1 6.8 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_19 PF13245.6 EIM87155.1 - 0.046 14.1 0.0 9.4 6.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 EIM87155.1 - 0.06 13.1 0.1 1.2 8.9 0.0 2.6 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 EIM87155.1 - 0.067 13.4 2.0 4.6 7.5 0.3 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EIM87155.1 - 0.082 12.3 2.1 7.4 5.9 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 EIM87155.1 - 0.085 12.1 0.2 7.3 5.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 EIM87155.1 - 0.11 12.6 0.1 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EIM87155.1 - 0.13 12.7 0.4 14 6.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EIM87155.1 - 1.1 9.8 11.9 1 9.8 0.0 2.9 4 0 0 4 4 2 0 AAA domain Pox_A32 PF04665.12 EIM87155.1 - 1.1 8.7 3.3 44 3.4 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein F-box-like PF12937.7 EIM87156.1 - 2.6e-05 24.0 0.9 2.6e-05 24.0 0.9 3.1 2 0 0 2 2 2 1 F-box-like Deltaretro_Tax PF05599.11 EIM87156.1 - 0.046 14.3 0.5 0.52 10.9 0.2 2.6 1 1 1 2 2 2 0 Deltaretrovirus Tax protein IL32 PF15225.6 EIM87156.1 - 0.096 13.1 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Interleukin 32 LRR_8 PF13855.6 EIM87156.1 - 1.1 9.1 5.6 14 5.5 0.8 3.3 2 2 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 EIM87156.1 - 3.8 8.1 13.0 11 6.6 0.7 4.9 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) N2227 PF07942.12 EIM87158.1 - 2.3e-92 309.0 0.0 2.9e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EIM87158.1 - 0.0036 17.2 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM87158.1 - 0.012 16.3 0.0 0.4 11.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIM87158.1 - 0.012 16.3 0.0 0.043 14.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Glyco_transf_90 PF05686.12 EIM87159.1 - 1.1e-12 47.6 0.3 2.2e-10 40.0 0.5 3.3 3 1 0 3 3 3 2 Glycosyl transferase family 90 PTPA PF03095.15 EIM87160.1 - 4.3e-126 420.4 0.0 5.1e-126 420.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FLILHELTA PF10306.9 EIM87161.1 - 7e-29 100.1 0.1 1.7e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EIM87161.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) UbiA PF01040.18 EIM87162.1 - 1.8e-46 158.5 14.6 2.2e-46 158.2 14.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ThrE_2 PF12821.7 EIM87162.1 - 6.6 6.9 10.3 1.1 9.4 0.2 3.2 2 1 1 3 3 3 0 Threonine/Serine exporter, ThrE NAD_binding_4 PF07993.12 EIM87163.1 - 2.6e-34 118.5 0.0 4.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM87163.1 - 5e-31 107.7 0.0 5.6e-30 104.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EIM87163.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM87163.1 - 0.00055 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EIM87163.1 - 0.0088 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EIM87163.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 KR domain RHD3 PF05879.12 EIM87164.1 - 2.3e-06 26.1 0.0 3.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EIM87164.1 - 6.4e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Isy1 PF06246.12 EIM87165.1 - 9.6e-94 313.7 0.2 1.6e-93 313.0 0.2 1.3 1 1 0 1 1 1 1 Isy1-like splicing family DUF4363 PF14276.6 EIM87165.1 - 0.071 13.2 1.5 0.082 13.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Conotoxin PF02950.17 EIM87166.1 - 5.5e-05 24.1 1.1 6.3e-05 23.9 1.1 1.1 1 0 0 1 1 1 1 Conotoxin Dickkopf_N PF04706.12 EIM87166.1 - 0.0049 17.3 2.3 0.0065 16.9 2.3 1.2 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.8 EIM87166.1 - 0.017 15.5 2.8 0.022 15.1 2.8 1.2 1 0 0 1 1 1 0 UPF0506 Conotoxin_I2 PF17557.2 EIM87166.1 - 0.018 15.1 4.5 0.024 14.8 4.5 1.2 1 0 0 1 1 1 0 I2-superfamily conotoxins Toxin_12 PF07740.12 EIM87166.1 - 0.13 12.9 6.2 0.2 12.4 6.2 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Toxin_27 PF08099.11 EIM87166.1 - 0.38 10.9 6.1 0.61 10.2 6.1 1.3 1 0 0 1 1 1 0 Scorpion calcine family ABC2_membrane PF01061.24 EIM87167.1 - 5.7e-76 254.6 45.3 1.9e-41 141.8 16.1 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EIM87167.1 - 1.7e-35 122.6 0.0 5.6e-17 62.5 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EIM87167.1 - 2.9e-31 107.2 16.0 3.7e-28 97.2 1.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EIM87167.1 - 5e-14 52.7 0.6 1.3e-13 51.4 0.6 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EIM87167.1 - 1.6e-07 31.8 0.0 0.00057 20.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM87167.1 - 2.3e-07 30.9 0.1 2e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EIM87167.1 - 3.3e-06 27.4 0.1 0.064 13.5 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EIM87167.1 - 5.3e-05 22.9 0.0 0.016 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIM87167.1 - 0.00035 21.1 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EIM87167.1 - 0.00044 19.9 0.6 0.23 11.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EIM87167.1 - 0.00062 20.0 0.0 0.55 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIM87167.1 - 0.00079 19.3 0.1 0.34 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EIM87167.1 - 0.0013 18.4 0.3 0.42 10.2 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 EIM87167.1 - 0.0017 17.6 23.1 0.0017 17.6 23.1 3.5 2 2 1 3 3 3 1 ABC-2 family transporter protein NACHT PF05729.12 EIM87167.1 - 0.0021 18.0 0.1 0.28 11.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EIM87167.1 - 0.0025 18.1 1.5 1.5 9.1 0.2 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 EIM87167.1 - 0.0026 17.8 0.0 0.66 10.1 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EIM87167.1 - 0.0057 16.4 0.2 4.2 7.1 0.3 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EIM87167.1 - 0.0065 15.8 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 2 Septin SbcCD_C PF13558.6 EIM87167.1 - 0.0071 16.6 1.2 6.1 7.2 0.0 3.0 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EIM87167.1 - 0.014 14.9 0.0 0.3 10.5 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain dNK PF01712.19 EIM87167.1 - 0.018 14.9 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_17 PF13207.6 EIM87167.1 - 0.019 15.4 0.1 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIM87167.1 - 0.054 13.9 0.0 13 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EIM87167.1 - 0.11 12.9 0.0 13 6.2 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EIM87167.1 - 0.12 12.1 0.9 2.1 8.0 0.6 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EIM87167.1 - 0.13 12.7 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIM87167.1 - 0.14 11.4 0.0 4.5 6.5 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 EIM87167.1 - 0.2 11.6 0.4 0.8 9.7 0.2 2.1 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sugar_tr PF00083.24 EIM87168.1 - 3.7e-108 362.3 25.4 4.4e-108 362.0 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM87168.1 - 5.2e-26 91.4 27.6 5.2e-26 91.4 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM87168.1 - 8.5e-07 27.8 4.0 8.5e-07 27.8 4.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EIM87168.1 - 0.0013 17.3 5.5 0.0019 16.7 2.1 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector Cation_efflux PF01545.21 EIM87169.1 - 3.1e-06 27.1 0.5 5.2e-06 26.3 0.5 1.4 1 0 0 1 1 1 1 Cation efflux family Phage_TAC_6 PF09550.10 EIM87169.1 - 0.0051 17.2 0.2 0.015 15.7 0.2 1.7 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC Archaeal_AmoA PF12942.7 EIM87172.1 - 0.017 14.8 0.3 0.038 13.7 0.3 1.6 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) SP_C-Propep PF08999.10 EIM87172.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2461 PF09365.10 EIM87173.1 - 2.6e-73 246.4 0.0 4.1e-73 245.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) ORC6 PF05460.13 EIM87173.1 - 0.11 11.7 37.5 0.15 11.3 12.1 2.8 2 1 1 3 3 3 0 Origin recognition complex subunit 6 (ORC6) AMP-binding PF00501.28 EIM87174.1 - 5e-96 321.9 0.1 7.2e-96 321.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM87174.1 - 3.2e-26 92.1 0.3 2e-24 86.4 0.1 3.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EIM87174.1 - 7e-15 54.7 1.4 2.4e-14 52.9 0.9 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Crp PF00325.20 EIM87174.1 - 0.045 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Sugar_tr PF00083.24 EIM87175.1 - 1.1e-74 251.9 26.9 1.3e-74 251.7 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM87175.1 - 3.8e-26 91.9 25.5 3.8e-26 91.9 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ProQ_C PF17516.2 EIM87176.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 ProQ C-terminal domain Amidohydro_2 PF04909.14 EIM87177.1 - 4.7e-20 72.6 0.0 6.8e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EIM87177.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase FMN_dh PF01070.18 EIM87178.1 - 2.2e-107 359.1 0.0 2.9e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EIM87178.1 - 8.4e-06 25.0 0.0 2e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EIM87178.1 - 0.00013 21.2 0.1 0.0002 20.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EIM87178.1 - 0.0003 20.2 0.0 0.44 9.8 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 EIM87178.1 - 0.058 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Sugar_tr PF00083.24 EIM87179.1 - 1.9e-32 112.7 29.5 1.9e-18 66.6 11.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EIM87179.1 - 1e-24 87.2 36.8 1.2e-12 47.5 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EIM87179.1 - 1e-06 27.6 25.7 0.00018 20.2 2.8 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein TGBp3 PF02495.17 EIM87179.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 Triple gene block 3 Peptidase_M24 PF00557.24 EIM87180.1 - 1.3e-43 149.2 0.0 1.7e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EIM87180.1 - 0.0044 17.7 0.1 0.01 16.5 0.0 1.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain TFIIA PF03153.13 EIM87181.1 - 0.00018 21.6 40.1 0.00034 20.8 40.1 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 EIM87181.1 - 0.049 12.6 4.8 0.076 12.0 4.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zn_clus PF00172.18 EIM87181.1 - 0.11 12.6 2.8 0.19 11.9 2.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2052 PF09747.9 EIM87181.1 - 0.61 10.2 11.7 1.1 9.4 11.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3292 PF11696.8 EIM87181.1 - 0.62 8.4 10.4 0.88 7.9 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PAS PF00989.25 EIM87181.1 - 0.72 9.9 0.0 0.72 9.9 0.0 2.6 2 1 1 3 3 3 0 PAS fold DUF913 PF06025.12 EIM87181.1 - 1.3 7.9 5.6 2.2 7.2 5.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 EIM87181.1 - 6.9 5.9 11.2 11 5.3 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_1 PF00232.18 EIM87182.1 - 1.6e-151 504.8 0.7 2e-151 504.5 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 EIM87182.1 - 0.037 13.6 0.0 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core DUF3127 PF11325.8 EIM87182.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) Mersacidin PF16934.5 EIM87182.1 - 0.18 11.6 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) GFO_IDH_MocA PF01408.22 EIM87183.1 - 9.6e-16 58.7 0.0 1.6e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EIM87183.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain BTB PF00651.31 EIM87184.1 - 0.013 15.7 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Sugar_tr PF00083.24 EIM87185.1 - 4.5e-113 378.5 23.0 5.6e-113 378.2 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM87185.1 - 5.6e-21 74.9 37.1 3e-17 62.6 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peroxidase_2 PF01328.17 EIM87186.1 - 1.7e-51 175.4 0.0 2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 JAB PF01398.21 EIM87188.1 - 1.3e-15 57.4 0.1 1.8e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EIM87188.1 - 6.8e-07 29.1 0.0 6.8e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Lamp PF01299.17 EIM87188.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF4329 PF14220.6 EIM87188.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4329) DUF3149 PF11346.8 EIM87189.1 - 2.3 7.9 4.5 6 6.6 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Pro_isomerase PF00160.21 EIM87190.1 - 7.7e-45 153.0 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_16 PF13432.6 EIM87190.1 - 0.019 15.6 0.6 0.047 14.4 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM87190.1 - 0.074 13.3 2.3 0.23 11.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP54 PF00448.22 EIM87190.1 - 0.12 12.0 1.3 0.18 11.4 1.3 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TPR_2 PF07719.17 EIM87190.1 - 0.12 12.5 3.3 0.55 10.5 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIM87190.1 - 0.16 11.8 0.7 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTB PF00651.31 EIM87193.1 - 0.00024 21.3 0.0 0.00045 20.4 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain DUF390 PF04094.14 EIM87193.1 - 1.6 6.9 6.0 3.5 5.8 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF390) HABP4_PAI-RBP1 PF04774.15 EIM87194.1 - 0.0004 21.2 4.6 0.00059 20.7 4.6 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Abhydrolase_3 PF07859.13 EIM87195.1 - 1.2e-16 61.2 0.0 3.2e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM87195.1 - 1.5e-12 47.1 0.0 6.9e-12 44.9 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 EIM87195.1 - 0.004 17.0 0.0 0.023 14.5 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EIM87195.1 - 0.13 11.7 0.1 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EIM87195.1 - 0.15 12.7 2.2 0.1 13.2 0.4 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.7 EIM87196.1 - 0.00012 21.9 2.0 0.00012 21.9 2.0 2.1 2 0 0 2 2 2 1 F-box-like DUF570 PF04489.13 EIM87196.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Cas6 PF09559.10 EIM87197.1 - 0.01 15.8 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 0 Cas6 Crispr T6PP_N PF18572.1 EIM87197.1 - 0.36 10.7 3.5 3.6 7.5 0.2 2.6 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SCFA_trans PF02667.14 EIM87200.1 - 0.07 12.1 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter DUF3206 PF11472.8 EIM87200.1 - 0.13 12.2 0.0 20 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) zf-MYND PF01753.18 EIM87201.1 - 9.7e-07 28.8 17.8 2e-06 27.8 17.8 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM87201.1 - 0.6 10.5 9.1 1.3 9.4 9.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3734 PF12536.8 EIM87202.1 - 0.12 12.7 0.4 0.21 11.9 0.4 1.3 1 0 0 1 1 1 0 Patatin phospholipase DUF202 PF02656.15 EIM87204.1 - 1.1e-06 29.0 0.7 5.1e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Glyco_hydro_18 PF00704.28 EIM87205.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 GPI-anchored PF10342.9 EIM87207.1 - 6.3e-07 30.1 0.1 8.3e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidase PF01425.21 EIM87208.1 - 9.1e-74 249.0 0.0 1.5e-72 245.0 0.0 2.0 1 1 0 1 1 1 1 Amidase zf-NOSIP PF15906.5 EIM87209.1 - 3.9e-13 49.3 0.5 9.1e-13 48.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 EIM87209.1 - 8.4e-11 41.6 16.2 1.4e-06 28.0 7.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM87209.1 - 6.8e-09 35.4 19.5 0.00015 21.6 9.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EIM87209.1 - 1e-08 34.9 13.7 2.1e-06 27.3 1.8 2.6 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.6 EIM87209.1 - 1e-07 32.2 16.8 9.5e-05 22.7 8.2 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 EIM87209.1 - 1.8e-07 31.1 15.4 0.00029 20.8 1.0 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 EIM87209.1 - 2.2e-07 30.7 20.1 1.4e-06 28.2 8.9 2.7 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM87209.1 - 2.9e-06 27.0 18.5 0.0048 16.7 2.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM87209.1 - 9.1e-06 25.4 19.9 0.0021 17.9 9.7 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EIM87209.1 - 2.8e-05 24.2 13.6 0.0076 16.4 1.1 2.6 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING FYVE PF01363.21 EIM87209.1 - 0.023 14.8 5.7 0.023 14.8 5.7 2.8 2 2 0 2 2 2 0 FYVE zinc finger zf-FLZ PF04570.14 EIM87209.1 - 0.065 12.7 1.5 17 5.0 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of the FCS-type, C2-C2 zinc-ribbons_6 PF07191.12 EIM87209.1 - 0.48 10.4 15.3 1 9.4 7.0 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-rbx1 PF12678.7 EIM87209.1 - 1.1 9.6 11.1 8.4 6.8 5.2 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain FCP1_C PF09309.10 EIM87209.1 - 1.3 8.9 8.3 0.17 11.8 3.6 1.8 2 1 0 2 2 2 0 FCP1, C-terminal DZR PF12773.7 EIM87209.1 - 2.5 8.2 15.1 3.3 7.8 6.7 3.3 2 1 1 3 3 3 0 Double zinc ribbon Vps39_2 PF10367.9 EIM87209.1 - 5.4 7.5 15.5 0.37 11.2 3.1 3.3 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 BTB PF00651.31 EIM87210.1 - 1.3e-08 35.1 0.0 2.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1115 PF06544.12 EIM87212.1 - 0.0042 17.2 0.0 0.0061 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Glyco_hydro_31 PF01055.26 EIM87213.1 - 2e-91 307.4 1.1 2.9e-91 306.9 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Spt5-NGN PF03439.13 EIM87216.1 - 9.8e-24 83.1 0.0 2.1e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EIM87216.1 - 1e-15 58.5 12.6 1e-15 58.5 12.6 3.3 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EIM87216.1 - 2.9e-12 46.1 15.3 5.1e-05 23.1 0.1 6.0 6 0 0 6 6 6 3 KOW motif CTD PF12815.7 EIM87216.1 - 1.6e-10 41.4 28.5 2.9e-06 27.7 20.9 2.4 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 SPT6_acidic PF14632.6 EIM87216.1 - 0.0052 17.3 13.7 0.0052 17.3 13.7 3.5 1 1 2 3 3 3 1 Acidic N-terminal SPT6 SDA1 PF05285.12 EIM87216.1 - 1.6 8.0 34.2 2.8 7.3 34.2 1.3 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.7 EIM87217.1 - 2.2e-10 40.2 0.2 2.2e-10 40.2 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM87217.1 - 1.3 9.0 5.1 11 6.1 5.1 2.5 1 1 0 1 1 1 0 F-box domain SH3_9 PF14604.6 EIM87218.1 - 0.061 13.2 2.0 0.063 13.2 0.5 1.8 2 0 0 2 2 2 0 Variant SH3 domain UvdE PF03851.14 EIM87219.1 - 1.2e-91 306.8 0.0 1.6e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE RhgB_N PF09284.10 EIM87220.1 - 7.3e-99 330.4 0.4 1.1e-98 329.8 0.4 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EIM87220.1 - 1.2e-33 116.3 0.0 4.8e-33 114.4 0.0 2.1 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EIM87220.1 - 2e-20 72.3 3.3 3.3e-20 71.7 2.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II F-box-like PF12937.7 EIM87221.1 - 7.9e-09 35.3 0.3 1.2e-08 34.7 0.3 1.3 1 0 0 1 1 1 1 F-box-like DUF5312 PF17239.2 EIM87221.1 - 0.088 11.1 0.1 0.1 11.0 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5312) F-box PF00646.33 EIM87221.1 - 0.26 11.2 4.5 2 8.4 4.5 2.1 1 1 0 1 1 1 0 F-box domain DUF543 PF04418.12 EIM87222.1 - 1.4e-28 98.7 0.1 1.5e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Hpt PF01627.23 EIM87224.1 - 1.9e-10 40.9 0.3 4.9e-10 39.5 0.2 1.7 1 1 0 1 1 1 1 Hpt domain DIOX_N PF14226.6 EIM87225.1 - 1.9e-18 67.3 0.0 3.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM87225.1 - 1.7e-13 50.9 0.0 9.9e-13 48.4 0.0 2.2 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EIM87226.1 - 2.8e-40 138.3 30.9 3.4e-39 134.8 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EIM87227.1 - 1.3e-42 146.0 34.4 3.4e-42 144.7 32.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM87227.1 - 2.6e-15 56.2 18.5 3.1e-10 39.5 12.0 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 EIM87227.1 - 6.3e-07 28.3 7.3 6.3e-07 28.3 7.3 2.7 3 1 1 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.13 EIM87227.1 - 1.5e-05 23.7 4.4 2.1e-05 23.2 4.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EIM87227.1 - 0.00042 19.3 8.6 0.021 13.7 8.0 2.5 1 1 0 1 1 1 1 MFS_1 like family ATG22 PF11700.8 EIM87227.1 - 0.0011 17.7 12.8 0.023 13.3 0.4 2.6 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like MFS_3 PF05977.13 EIM87227.1 - 0.002 16.6 5.6 0.0033 15.9 5.6 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector PI-PLC-X PF00388.19 EIM87228.1 - 2.7e-53 179.5 0.0 4.6e-53 178.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EIM87228.1 - 1.5e-44 151.0 0.1 4e-44 149.6 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EIM87228.1 - 1.7e-08 34.6 0.0 0.0065 16.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 EIM87228.1 - 0.035 14.6 0.1 0.094 13.2 0.1 1.7 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_10 PF14788.6 EIM87228.1 - 0.041 13.7 0.2 0.083 12.8 0.2 1.5 1 0 0 1 1 1 0 EF hand MFS_1 PF07690.16 EIM87229.1 - 5.7e-42 143.9 31.8 5.7e-42 143.9 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM87229.1 - 1.5e-10 40.6 10.6 1.5e-10 40.6 10.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EIM87229.1 - 1.5e-06 27.4 4.9 9.7e-05 21.4 0.4 3.0 2 1 1 3 3 3 2 MFS_1 like family TRI12 PF06609.13 EIM87229.1 - 1.8e-06 26.7 2.1 2.7e-06 26.1 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EIM87229.1 - 5.3e-05 22.0 11.6 5.3e-05 22.0 11.6 3.1 3 2 0 3 3 3 1 MFS/sugar transport protein MFS_4 PF06779.14 EIM87229.1 - 6.9e-05 22.3 5.4 6.9e-05 22.3 5.4 2.7 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EIM87229.1 - 0.00014 20.5 4.7 0.00022 19.8 4.7 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector ATG22 PF11700.8 EIM87229.1 - 0.00029 19.6 9.0 0.057 12.1 2.0 2.7 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Transgly_assoc PF04226.13 EIM87229.1 - 0.0047 17.1 3.8 0.0047 17.1 3.8 2.5 2 0 0 2 2 2 1 Transglycosylase associated protein Antimicrobial17 PF08129.11 EIM87229.1 - 3 7.9 3.8 31 4.6 0.0 3.9 5 0 0 5 5 5 0 Alpha/beta enterocin family BT1 PF03092.16 EIM87229.1 - 3.9 5.6 11.6 0.15 10.3 3.3 2.2 2 0 0 2 2 2 0 BT1 family MFS_1 PF07690.16 EIM87230.1 - 2.6e-35 122.0 32.9 2.6e-35 122.0 32.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily COX2-transmemb PF09125.10 EIM87230.1 - 1.3 8.9 5.1 6 6.7 5.1 2.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Peroxidase_2 PF01328.17 EIM87232.1 - 3.4e-52 177.7 0.0 4.1e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Seryl_tRNA_N PF02403.22 EIM87234.1 - 0.073 13.3 0.1 0.1 12.8 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2205 PF10224.9 EIM87234.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Short coiled-coil protein F-box-like PF12937.7 EIM87235.1 - 7.6e-05 22.5 0.4 7.6e-05 22.5 0.4 2.5 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 EIM87235.1 - 0.0029 17.5 0.3 0.015 15.2 0.0 2.3 3 0 0 3 3 3 1 F-box Peroxin-3 PF04882.12 EIM87236.1 - 1.1e-132 443.4 0.0 3.7e-132 441.7 0.0 1.7 1 1 0 1 1 1 1 Peroxin-3 But2 PF09792.9 EIM87239.1 - 7.8e-09 36.1 0.0 1.5e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Peroxidase_2 PF01328.17 EIM87240.1 - 1.2e-52 179.2 0.0 1.4e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 NmrA PF05368.13 EIM87241.1 - 5.7e-26 91.5 0.0 7e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM87241.1 - 5.7e-11 42.6 0.0 2.6e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM87241.1 - 2.9e-06 27.6 0.1 8.2e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EIM87241.1 - 1.7e-05 25.0 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EIM87241.1 - 4.2e-05 23.6 0.0 6.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 EIM87241.1 - 0.00029 19.9 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Viral_DNA_bi PF02236.17 EIM87241.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Viral DNA-binding protein, all alpha domain NAD_binding_3 PF03447.16 EIM87241.1 - 0.0057 17.3 0.1 4.9 7.8 0.0 2.4 1 1 1 2 2 2 2 Homoserine dehydrogenase, NAD binding domain ApbA PF02558.16 EIM87241.1 - 0.017 14.8 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KR PF08659.10 EIM87241.1 - 0.055 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 KR domain Glu_dehyd_C PF16912.5 EIM87241.1 - 0.069 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF2095 PF09868.9 EIM87241.1 - 0.089 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) WD40 PF00400.32 EIM87242.1 - 1.1e-22 79.8 1.9 3e-05 24.7 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM87242.1 - 3.5e-12 46.5 0.0 0.003 17.8 0.0 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM87242.1 - 9.1e-06 25.7 0.3 0.0069 16.3 0.1 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3824 PF12868.7 EIM87242.1 - 1.4 9.6 12.5 0.43 11.2 8.0 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Proteasome_A_N PF10584.9 EIM87242.1 - 4.8 6.9 4.9 39 4.1 0.1 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Nup54 PF13874.6 EIM87243.1 - 7.3e-36 123.3 0.9 7.3e-36 123.3 0.9 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EIM87243.1 - 3.4e-19 69.5 123.7 1.1e-07 32.6 38.2 5.1 2 2 0 3 3 3 3 Nucleoporin FG repeat region Nup54_C PF18437.1 EIM87243.1 - 7.1e-05 22.6 2.2 7.1e-05 22.6 2.2 2.2 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain RNaseH_pPIWI_RE PF13032.6 EIM87243.1 - 0.29 11.0 2.9 1.9 8.3 0.5 2.6 1 1 0 2 2 2 0 RNaseH domain of pPIWI_RE HWE_HK PF07536.14 EIM87243.1 - 0.91 10.3 4.0 7.7 7.3 1.7 3.1 3 0 0 3 3 3 0 HWE histidine kinase dsrm PF00035.26 EIM87244.1 - 2.9e-05 24.7 0.0 3.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif ChaC PF04752.12 EIM87244.1 - 0.076 13.1 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein Asp PF00026.23 EIM87245.1 - 1.5e-40 139.5 8.1 7.5e-40 137.3 8.1 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM87245.1 - 8.6e-07 29.4 4.4 0.00011 22.5 0.1 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM87245.1 - 0.0055 17.3 4.8 0.023 15.3 0.9 2.7 2 0 0 2 2 2 1 Aspartyl protease FAD_binding_4 PF01565.23 EIM87246.1 - 3.4e-19 69.0 3.6 5.7e-19 68.2 3.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM87246.1 - 0.00012 22.1 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like VBS PF08913.10 EIM87246.1 - 0.13 12.7 0.1 0.41 11.1 0.1 1.8 1 0 0 1 1 1 0 Vinculin Binding Site Ribosomal_L27e PF01777.18 EIM87247.1 - 2.4e-35 120.7 4.3 3.4e-35 120.3 4.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EIM87247.1 - 0.084 12.9 0.6 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 KOW motif PfkB PF00294.24 EIM87248.1 - 1.9e-18 66.8 0.2 5.2e-18 65.4 0.2 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase BTB PF00651.31 EIM87249.1 - 5e-06 26.7 0.0 1e-05 25.7 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EIM87250.1 - 2.8e-05 24.3 0.0 4.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM87251.1 - 0.061 13.5 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain STPPase_N PF16891.5 EIM87251.1 - 0.2 12.1 1.1 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain TFIIS_C PF01096.18 EIM87252.1 - 3.7e-12 45.9 2.8 3.7e-12 45.9 2.8 2.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EIM87252.1 - 5.9e-09 35.7 0.9 5.9e-09 35.7 0.9 3.6 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 EIM87252.1 - 0.0036 17.7 0.3 0.0036 17.7 0.3 2.2 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf-ACC PF17848.1 EIM87252.1 - 0.014 15.5 10.4 0.98 9.6 0.2 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain GFA PF04828.14 EIM87252.1 - 0.015 15.6 6.6 0.8 10.1 3.5 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF3268 PF11672.8 EIM87252.1 - 0.037 14.3 3.8 0.26 11.6 0.1 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain Zn_ribbon_recom PF13408.6 EIM87252.1 - 0.11 13.0 6.5 0.63 10.6 1.2 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DpnI PF06044.12 EIM87252.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 Dam-replacing family RecR PF02132.15 EIM87252.1 - 0.14 11.8 0.5 0.14 11.8 0.5 3.1 3 0 0 3 3 3 0 RecR protein zf_UBZ PF18439.1 EIM87252.1 - 0.18 11.4 9.1 3.4 7.4 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 EIM87252.1 - 0.24 11.5 10.7 0.24 11.4 2.9 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like ADK_lid PF05191.14 EIM87252.1 - 0.27 11.2 3.3 25 4.9 0.0 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid PhnA_Zn_Ribbon PF08274.12 EIM87252.1 - 0.28 11.2 0.3 0.28 11.2 0.3 2.8 4 0 0 4 4 3 0 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.10 EIM87252.1 - 0.46 10.3 7.5 6.4 6.6 0.0 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 EIM87252.1 - 0.58 9.7 0.1 0.58 9.7 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-RRN7 PF11781.8 EIM87252.1 - 0.59 9.9 5.6 25 4.7 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 EIM87252.1 - 0.62 10.1 11.9 1.9 8.6 1.8 2.7 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EIM87252.1 - 0.8 9.5 11.3 0.46 10.3 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 EIM87252.1 - 0.88 9.6 10.5 0.15 12.0 2.0 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF2072 PF09845.9 EIM87252.1 - 1.1 9.5 4.7 6 7.1 0.0 2.8 3 0 0 3 3 3 0 Zn-ribbon containing protein C1_4 PF07975.12 EIM87252.1 - 2 8.7 14.7 22 5.4 3.6 3.8 2 2 2 4 4 4 0 TFIIH C1-like domain zf_C2H2_10 PF18414.1 EIM87252.1 - 2 8.0 5.6 5.7 6.6 0.2 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger Zn-ribbon_8 PF09723.10 EIM87252.1 - 3.9 7.7 10.4 3.8 7.7 0.1 3.5 3 1 0 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.16 EIM87252.1 - 4.6 7.5 10.9 5.9 7.1 0.3 3.6 3 1 0 3 3 3 0 AN1-like Zinc finger Rpr2 PF04032.16 EIM87252.1 - 5.5 7.3 9.5 3.5e+02 1.6 9.5 3.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain IBR PF01485.21 EIM87252.1 - 6 7.2 12.2 1.1e+03 -0.1 12.2 2.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain CpXC PF14353.6 EIM87252.1 - 6.6 6.8 7.6 0.57 10.2 1.1 2.3 2 2 0 2 2 2 0 CpXC protein zinc_ribbon_13 PF09855.9 EIM87252.1 - 7.1 6.9 9.0 18 5.6 0.2 3.2 2 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Ifi-6-16 PF06140.13 EIM87253.1 - 1.4e-07 31.3 31.9 1.4e-07 31.3 31.9 2.1 1 1 1 2 2 2 1 Interferon-induced 6-16 family F-box-like PF12937.7 EIM87254.1 - 2e-07 30.8 1.5 1.7e-06 27.8 1.5 2.4 1 1 0 1 1 1 1 F-box-like SNF5 PF04855.12 EIM87255.1 - 1e-66 225.2 0.7 1.7e-66 224.4 0.7 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HNH_2 PF13391.6 EIM87258.1 - 3.4e-05 23.9 0.0 7.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.16 EIM87259.1 - 4.2e-22 78.5 38.8 5.9e-22 78.1 38.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_7 PF03441.14 EIM87260.1 - 2.9e-45 154.2 0.2 4.4e-45 153.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EIM87260.1 - 4.4e-20 72.3 0.0 7.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase 120_Rick_ant PF12574.8 EIM87261.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen RRN9 PF10680.9 EIM87261.1 - 0.83 10.0 3.5 0.35 11.2 0.4 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor TubC_N PF18563.1 EIM87262.1 - 0.027 14.4 0.1 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 TubC N-terminal docking domain DUF5319 PF17252.2 EIM87262.1 - 0.031 14.5 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5319) BST2 PF16716.5 EIM87265.1 - 0.047 14.3 2.1 0.098 13.2 2.1 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 MscS_porin PF12795.7 EIM87265.1 - 0.96 8.9 7.4 0.1 12.1 2.9 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF2848 PF11010.8 EIM87266.1 - 0.057 13.0 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) Abhydrolase_2 PF02230.16 EIM87268.1 - 1.8e-12 47.5 0.0 4.3e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase COesterase PF00135.28 EIM87269.1 - 8.4e-80 269.1 2.1 1.1e-78 265.3 2.1 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM87269.1 - 0.0013 18.6 0.3 0.0076 16.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1308 PF07000.11 EIM87270.1 - 0.00013 21.9 0.1 0.2 11.6 0.0 3.1 4 0 0 4 4 4 2 Protein of unknown function (DUF1308) DUF5614 PF18474.1 EIM87270.1 - 0.017 14.5 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5614) DUF4632 PF15451.6 EIM87270.1 - 0.056 13.5 2.1 0.41 10.7 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) GAIN_A PF18619.1 EIM87270.1 - 0.13 12.5 0.2 3.7 7.8 0.0 2.6 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A UcrQ PF02939.16 EIM87271.1 - 2.1e-27 94.8 0.8 2.5e-27 94.6 0.8 1.1 1 0 0 1 1 1 1 UcrQ family Peptidase_M20 PF01546.28 EIM87272.1 - 5.4e-31 107.9 0.0 5.2e-30 104.7 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM87272.1 - 1.1e-09 38.1 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM87272.1 - 0.00014 21.7 0.0 0.0003 20.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 CRC_subunit PF08624.10 EIM87273.1 - 2.9e-44 150.8 0.0 4.4e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Abhydrolase_6 PF12697.7 EIM87275.1 - 1.2e-12 48.9 0.4 1.5e-12 48.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIM87275.1 - 5.5e-05 22.7 0.0 0.0002 20.9 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EIM87275.1 - 0.00062 19.5 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM87275.1 - 0.00083 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EIM87275.1 - 0.0025 16.6 0.0 0.87 8.2 0.0 2.2 2 0 0 2 2 2 2 Ndr family PAF-AH_p_II PF03403.13 EIM87275.1 - 0.015 13.8 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 EIM87275.1 - 0.05 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S41 PF03572.18 EIM87276.1 - 3.3e-05 23.5 0.0 6.9e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Aldedh PF00171.22 EIM87277.1 - 8.3e-115 383.9 0.0 1.2e-114 383.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 EIM87278.1 - 8.9e-74 248.8 0.0 1.8e-73 247.8 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM87278.1 - 0.00012 21.5 0.4 0.093 11.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM87278.1 - 0.00065 20.2 0.1 0.14 12.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM87278.1 - 0.00076 18.3 0.2 0.036 12.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EIM87278.1 - 0.002 18.3 0.0 0.0059 16.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM87278.1 - 0.011 15.3 0.1 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM87278.1 - 0.011 15.0 0.2 0.033 13.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM87278.1 - 0.043 12.9 0.1 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EIM87278.1 - 0.072 11.9 0.1 8.8 5.1 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Peptidase_S41 PF03572.18 EIM87280.1 - 0.00018 21.1 0.0 0.00057 19.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 EPL1 PF10513.9 EIM87281.1 - 5.5e-21 75.6 0.5 4e-20 72.8 0.0 2.6 2 0 0 2 2 2 1 Enhancer of polycomb-like Acetyltransf_3 PF13302.7 EIM87283.1 - 1.6e-09 38.6 0.0 2.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M20 PF01546.28 EIM87284.1 - 3.7e-27 95.4 0.0 7e-27 94.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM87284.1 - 7.1e-12 45.2 0.1 2.4e-11 43.5 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM87284.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIM87285.1 - 9.8e-25 87.5 0.0 2.1e-24 86.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM87285.1 - 5.1e-12 45.7 0.0 1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Glyco_transf_18 PF15024.6 EIM87286.1 - 1.5e-13 50.2 0.0 2.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 WD40 PF00400.32 EIM87287.1 - 1e-38 130.6 17.7 1.2e-07 32.2 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EIM87287.1 - 4.3e-11 42.5 3.0 9.4e-11 41.4 3.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM87287.1 - 1.2e-09 37.8 1.0 2.4e-09 36.8 1.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EIM87287.1 - 3.5e-09 36.8 0.0 0.0048 17.2 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM87287.1 - 4.3e-06 25.6 0.2 1.7 7.2 0.0 4.4 4 1 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM87287.1 - 0.00032 20.1 0.0 0.14 11.5 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 EIM87287.1 - 0.009 15.6 0.1 0.77 9.3 0.0 2.9 2 1 0 3 3 3 1 PQQ-like domain DUF5046 PF16465.5 EIM87287.1 - 0.12 11.7 0.0 12 5.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5046) UPF0139 PF03669.13 EIM87288.1 - 1.9e-08 34.0 0.0 2.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Acyl_transf_3 PF01757.22 EIM87288.1 - 0.014 14.4 0.1 0.016 14.3 0.1 1.0 1 0 0 1 1 1 0 Acyltransferase family SET PF00856.28 EIM87289.1 - 2.4e-21 76.8 0.1 1.7e-20 74.1 0.1 2.1 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 EIM87289.1 - 0.027 14.6 0.5 0.068 13.3 0.8 1.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N COXG PF06240.13 EIM87289.1 - 0.099 12.4 0.1 0.74 9.6 0.0 1.9 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) zf-C2H2 PF00096.26 EIM87290.1 - 2.8e-05 24.3 2.8 0.0013 19.0 0.6 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM87290.1 - 0.00052 20.6 1.9 0.1 13.5 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger WD40 PF00400.32 EIM87291.1 - 4.1e-10 40.1 6.3 0.029 15.2 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM87291.1 - 0.0069 16.7 0.0 19 5.6 0.0 4.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIM87291.1 - 0.032 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Mpp10 PF04006.12 EIM87291.1 - 1.2 7.5 17.7 1.7 7.0 17.7 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 EIM87291.1 - 1.9 7.7 18.7 2.8 7.2 18.7 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_M20 PF01546.28 EIM87292.1 - 1.4e-29 103.3 0.0 4.6e-29 101.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM87292.1 - 9e-11 41.7 0.1 2.4e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM87292.1 - 2.5e-06 27.3 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 CHAT PF12770.7 EIM87293.1 - 1.8e-34 119.5 0.0 3.9e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM87293.1 - 6.2e-24 83.1 15.6 0.0041 17.0 0.0 12.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 EIM87293.1 - 9.2e-08 31.6 9.7 0.4 10.8 0.0 8.4 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIM87293.1 - 1.5e-07 31.6 20.5 0.042 14.1 0.5 8.7 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM87293.1 - 0.00073 19.5 8.5 3.3 8.0 0.2 8.0 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM87293.1 - 0.00093 19.2 2.6 5.9 7.4 0.1 7.1 10 0 0 10 10 10 1 Tetratricopeptide repeat T3SS_ATPase_C PF18269.1 EIM87293.1 - 0.11 12.3 2.6 2.8 7.9 0.0 4.2 5 0 0 5 5 5 0 T3SS EscN ATPase C-terminal domain Shikimate_DH PF01488.20 EIM87293.1 - 0.13 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CRISPR_Cse2 PF09485.10 EIM87293.1 - 0.23 12.0 9.6 2.2 8.8 0.1 5.0 3 2 1 5 5 5 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_4 PF07721.14 EIM87293.1 - 7.9 7.4 7.7 4.6 8.2 0.6 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Helitron_like_N PF14214.6 EIM87295.1 - 5.1e-27 95.3 0.0 9.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus rve PF00665.26 EIM87302.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain CSD2 PF17876.1 EIM87305.1 - 0.067 13.4 0.0 1 9.6 0.0 2.4 3 0 0 3 3 3 0 Cold shock domain F-box PF00646.33 EIM87308.1 - 4.3e-05 23.3 0.1 8.6e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM87308.1 - 0.00018 21.3 0.1 0.00041 20.2 0.0 1.7 2 0 0 2 2 2 1 F-box-like Thr_synth_N PF14821.6 EIM87312.1 - 6e-28 96.9 0.1 2e-27 95.2 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EIM87312.1 - 2e-16 60.3 0.1 1.9e-15 57.0 0.1 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_2b PF00587.25 EIM87313.1 - 5.2e-38 130.8 0.1 4.1e-37 127.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EIM87313.1 - 6.6e-21 74.6 4.6 6.6e-21 74.6 4.6 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Nop14 PF04147.12 EIM87314.1 - 0.85 7.7 10.1 0.98 7.5 10.1 1.0 1 0 0 1 1 1 0 Nop14-like family Plasmodium_Vir PF05795.11 EIM87314.1 - 6.8 6.0 4.9 8.4 5.7 4.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BTB PF00651.31 EIM87315.1 - 0.0005 20.3 0.0 0.0012 19.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM87316.1 - 9e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM87317.1 - 2.4e-05 24.5 0.0 7.1e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Ribonuc_2-5A PF06479.12 EIM87319.1 - 3.3e-46 156.6 0.0 5.7e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EIM87319.1 - 1.1e-36 126.6 0.0 2.7e-28 99.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87319.1 - 8.9e-17 61.2 0.0 6.5e-15 55.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EIM87319.1 - 0.00012 21.8 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat Pkinase_fungal PF17667.1 EIM87319.1 - 0.0038 16.1 0.0 0.0078 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PQQ_2 PF13360.6 EIM87319.1 - 0.0081 15.8 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain DUF4407 PF14362.6 EIM87320.1 - 0.15 11.4 5.6 0.24 10.7 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SpecificRecomb PF10136.9 EIM87320.1 - 0.23 9.7 2.5 0.34 9.2 2.5 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF948 PF06103.11 EIM87320.1 - 0.24 11.7 0.7 0.8 10.0 0.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 EIM87320.1 - 0.91 9.3 2.8 2.5 7.9 2.8 1.6 1 0 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.8 EIM87320.1 - 0.92 9.7 3.2 0.99 9.6 0.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 EIM87320.1 - 1.2 7.5 9.1 2.2 6.7 9.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Med21 PF11221.8 EIM87320.1 - 1.4 9.2 5.5 1.9 8.7 1.4 3.3 3 0 0 3 3 3 0 Subunit 21 of Mediator complex ABC_tran_CTD PF16326.5 EIM87320.1 - 1.5 9.2 7.2 3.6 7.9 1.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain LPP PF04728.13 EIM87320.1 - 5.8 7.4 8.9 3.8 8.0 2.5 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Asp PF00026.23 EIM87321.1 - 1.6e-47 162.5 6.3 2e-47 162.1 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EIM87321.1 - 0.00079 20.0 1.1 0.89 10.2 0.1 3.8 3 0 0 3 3 3 1 Aspartyl protease TAXi_N PF14543.6 EIM87321.1 - 0.023 14.9 2.6 0.16 12.2 0.5 2.9 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EIM87321.1 - 0.053 14.1 0.4 1.9 9.1 0.0 3.5 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 EIM87321.1 - 0.1 12.9 1.6 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease STAG PF08514.11 EIM87322.1 - 5.4e-35 119.7 0.1 2.8e-34 117.4 0.1 2.4 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 EIM87322.1 - 2.7e-08 34.1 0.0 2.8e-06 27.6 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EIM87322.1 - 5.8e-06 26.1 1.8 4.2 7.9 0.1 5.9 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.25 EIM87323.1 - 3.8e-37 128.1 0.0 5.6e-26 91.5 0.0 3.1 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87323.1 - 1e-15 57.7 0.0 2.5e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIM87323.1 - 0.00081 18.8 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EIM87323.1 - 0.99 8.1 2.3 0.53 9.0 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF3810 PF12725.7 EIM87324.1 - 5.4 6.3 4.7 10 5.3 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) EHN PF06441.12 EIM87325.1 - 2.6e-31 108.2 0.5 9.5e-30 103.2 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EIM87325.1 - 4.7e-14 52.7 0.4 6.9e-14 52.1 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM87325.1 - 0.0011 19.7 9.8 0.0011 19.7 9.8 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF2183 PF09949.9 EIM87326.1 - 1.5e-32 111.9 0.0 2.7e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pkinase PF00069.25 EIM87327.1 - 5.3e-19 68.6 0.0 8.7e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87327.1 - 9.2e-10 38.2 0.0 2.5e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM87327.1 - 7.4e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM87327.1 - 0.095 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMCO5 PF14992.6 EIM87328.1 - 0.4 10.2 1.6 0.81 9.2 1.6 1.4 1 0 0 1 1 1 0 TMCO5 family Pkinase PF00069.25 EIM87329.1 - 2.8e-41 141.6 0.0 2.3e-31 109.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87329.1 - 3.1e-13 49.6 0.0 1.5e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIM87329.1 - 0.0033 17.4 1.4 0.58 10.0 0.5 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EIM87329.1 - 0.0073 15.7 0.2 0.014 14.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FIBP PF05427.11 EIM87329.1 - 0.15 11.3 0.4 0.23 10.7 0.4 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) HMG14_17 PF01101.18 EIM87329.1 - 0.33 11.9 4.9 0.99 10.4 4.9 1.8 1 0 0 1 1 1 0 HMG14 and HMG17 zf-C3HC4_2 PF13923.6 EIM87330.1 - 1.2e-06 28.3 5.9 1.2e-06 28.3 5.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM87330.1 - 4.9e-06 26.5 8.3 1.2e-05 25.2 8.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM87330.1 - 7.8e-06 26.0 8.2 7.8e-06 26.0 8.2 2.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EIM87330.1 - 8.1e-06 25.6 6.3 8.1e-06 25.6 6.3 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM87330.1 - 7.3e-05 22.6 9.1 7.3e-05 22.6 9.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM87330.1 - 0.00013 21.8 8.3 0.00013 21.8 8.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EIM87330.1 - 0.0032 17.8 13.4 0.0032 17.8 13.4 2.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 EIM87330.1 - 0.01 15.7 1.2 0.01 15.7 1.2 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Glutaredoxin PF00462.24 EIM87330.1 - 0.22 11.8 1.5 1.6 9.0 0.2 2.6 2 0 0 2 2 2 0 Glutaredoxin DUF35_N PF12172.8 EIM87330.1 - 0.45 10.5 5.3 19 5.3 0.1 3.4 2 1 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 EIM87331.1 - 6.2e-17 61.8 0.0 8.2e-16 58.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EIM87331.1 - 2e-16 60.0 12.2 1e-07 32.5 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 EIM87331.1 - 2.8e-10 39.6 12.7 0.0059 16.8 0.1 6.5 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.17 EIM87331.1 - 3.1e-07 30.0 0.0 0.026 13.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.6 EIM87331.1 - 3.9e-06 27.2 0.7 0.83 10.1 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats Cohesin_HEAT PF12765.7 EIM87331.1 - 0.0024 18.2 1.8 0.98 9.8 0.1 2.8 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Tti2 PF10521.9 EIM87331.1 - 0.066 12.7 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Tti2 family Adaptin_N PF01602.20 EIM87331.1 - 0.22 10.0 1.1 6.8 5.1 0.2 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 EIM87331.1 - 0.92 10.1 10.3 7.3 7.2 0.1 4.6 4 0 0 4 4 4 0 HEAT-like repeat F-box-like PF12937.7 EIM87332.1 - 1.5e-11 44.0 0.4 4.2e-11 42.6 0.4 1.9 1 0 0 1 1 1 1 F-box-like Anti-TRAP PF15777.5 EIM87333.1 - 0.0089 16.0 1.1 0.62 10.1 0.1 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Prim_Zn_Ribbon PF08273.12 EIM87333.1 - 1.7 9.0 8.0 19 5.7 3.6 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase adh_short PF00106.25 EIM87334.1 - 3.9e-17 62.4 0.1 6.5e-15 55.1 0.2 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EIM87334.1 - 1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EIM87334.1 - 1.8e-05 24.4 0.4 9.5e-05 22.1 0.2 2.1 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM87335.1 - 1.1e-16 60.9 0.1 8.4e-16 58.0 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EIM87335.1 - 1.3e-08 35.0 0.1 2.1e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EIM87335.1 - 8.6e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM87337.1 - 1.6e-18 66.9 0.2 5.2e-16 58.7 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87337.1 - 3.1e-09 36.8 0.5 2.8e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87337.1 - 1.1e-07 32.0 0.1 1.7e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM87337.1 - 0.03 13.5 0.2 0.087 11.9 0.1 1.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein HSP20 PF00011.21 EIM87338.1 - 1.3e-11 44.5 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EIM87338.1 - 0.00037 20.0 0.0 0.00084 18.9 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF2457 PF10446.9 EIM87338.1 - 9.5 5.2 10.1 13 4.8 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) adh_short PF00106.25 EIM87339.1 - 2.4e-15 56.5 0.0 6.5e-14 51.8 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87339.1 - 1.6e-07 31.2 0.0 3.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87339.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain APH PF01636.23 EIM87340.1 - 1.4e-14 54.6 0.1 2.4e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM87340.1 - 0.00019 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EIM87340.1 - 0.049 13.0 0.0 7.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain adh_short PF00106.25 EIM87341.1 - 6.1e-17 61.7 1.8 6.8e-15 55.0 0.6 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87341.1 - 1.5e-09 37.7 1.2 4.6e-07 29.6 0.3 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87341.1 - 1.5e-05 25.0 0.2 2.4e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EIM87342.1 - 6.7e-19 68.1 0.0 2e-16 60.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87342.1 - 3.6e-09 36.5 0.0 1.5e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87342.1 - 1.3e-07 31.7 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 KR domain tRNA-synt_2b PF00587.25 EIM87343.1 - 2.5e-35 122.1 0.0 4.5e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EIM87343.1 - 1.9e-17 63.2 0.0 5.2e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 EIM87343.1 - 1.4e-15 57.0 0.0 2.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 EIM87343.1 - 1.2e-12 47.7 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CSTF2_hinge PF14327.6 EIM87344.1 - 1.5e-27 95.9 2.4 2.5e-27 95.1 2.4 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EIM87344.1 - 2.9e-21 75.1 0.0 4.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM87344.1 - 0.01 16.0 0.1 0.04 14.1 0.1 2.1 2 1 0 2 2 2 0 RNA recognition motif IATP PF04568.12 EIM87344.1 - 0.15 12.5 0.3 0.39 11.2 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP adh_short PF00106.25 EIM87345.1 - 3.2e-17 62.6 0.2 4.5e-16 58.9 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87345.1 - 9.8e-09 35.1 0.3 2.5e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87345.1 - 7.3e-08 32.5 0.2 1.4e-07 31.6 0.1 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EIM87345.1 - 0.0097 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein HMA PF00403.26 EIM87345.1 - 0.19 12.2 0.4 1.2 9.7 0.4 2.3 3 0 0 3 3 3 0 Heavy-metal-associated domain adh_short PF00106.25 EIM87346.1 - 2.4e-15 56.5 0.0 5.2e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87346.1 - 3.1e-08 33.5 0.0 4.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87346.1 - 2.1e-06 27.8 0.2 3.7e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 KR domain zf-rbx1 PF12678.7 EIM87349.1 - 2.8e-24 85.2 12.9 3.9e-24 84.7 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EIM87349.1 - 1.5e-16 60.2 9.6 1.9e-16 59.9 9.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EIM87349.1 - 7.7e-06 26.1 15.4 0.0003 21.1 15.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM87349.1 - 0.0012 18.6 11.8 0.024 14.5 11.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM87349.1 - 0.0015 18.3 14.6 0.0019 18.0 9.1 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EIM87349.1 - 0.19 11.9 9.3 0.93 9.7 9.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EIM87349.1 - 0.22 11.4 10.9 0.68 9.8 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM87349.1 - 0.26 11.4 7.1 0.86 9.7 7.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EIM87349.1 - 0.53 9.9 14.3 0.17 11.5 4.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EIM87349.1 - 1.6 8.6 17.0 87 3.0 17.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger TBCC PF07986.12 EIM87351.1 - 7.8e-13 48.2 2.8 2.9e-12 46.4 2.8 1.9 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EIM87351.1 - 3.6e-10 40.3 0.8 6.8e-10 39.4 0.8 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain AAA_13 PF13166.6 EIM87351.1 - 0.068 11.8 0.3 0.089 11.4 0.3 1.1 1 0 0 1 1 1 0 AAA domain ATP-synt PF00231.19 EIM87355.1 - 6.3e-82 275.4 6.7 7.1e-82 275.3 6.7 1.0 1 0 0 1 1 1 1 ATP synthase DUF4694 PF15765.5 EIM87355.1 - 0.035 14.1 0.3 0.069 13.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) Bac_rhamnosid_N PF08531.10 EIM87355.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain eIF-5_eIF-2B PF01873.17 EIM87356.1 - 1.6e-41 140.8 0.0 2.8e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EIM87356.1 - 0.0033 16.9 0.1 0.0089 15.5 0.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.12 EIM87356.1 - 0.12 12.1 0.1 23 4.9 0.0 2.5 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 EIM87356.1 - 1.1 9.7 4.3 14 6.1 0.0 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain RRM_1 PF00076.22 EIM87357.1 - 8.5e-06 25.5 0.0 0.00024 20.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Topoisom_I PF01028.20 EIM87357.1 - 0.031 13.5 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core zf_CCCH_4 PF18345.1 EIM87358.1 - 2.3e-14 52.9 38.7 2.1e-06 27.6 3.6 5.1 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 EIM87358.1 - 5.2e-14 51.7 33.2 7.3e-06 25.7 1.7 4.7 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH PF00642.24 EIM87358.1 - 4e-12 45.7 31.7 0.00013 21.7 2.7 4.2 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EIM87358.1 - 3.6e-10 40.5 14.8 0.00064 20.4 0.4 4.0 2 1 2 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 EIM87358.1 - 3.5e-07 30.4 3.9 0.018 15.2 0.1 3.5 1 1 2 3 3 3 3 Zinc-finger containing family zf-CCCH_2 PF14608.6 EIM87358.1 - 0.0016 18.9 30.7 0.0044 17.4 3.9 4.4 4 0 0 4 4 4 2 RNA-binding, Nab2-type zinc finger F-box-like PF12937.7 EIM87359.1 - 0.0015 18.4 0.3 0.0075 16.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like Peptidase_S41 PF03572.18 EIM87360.1 - 0.0026 17.3 0.0 0.0051 16.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 F_bP_aldolase PF01116.20 EIM87361.1 - 3.9e-93 312.0 0.5 4.4e-93 311.8 0.5 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Lipase_GDSL_2 PF13472.6 EIM87361.1 - 0.014 15.8 0.1 0.022 15.1 0.1 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.7 EIM87362.1 - 8e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM87362.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain zf-C2H2_4 PF13894.6 EIM87362.1 - 0.39 11.7 1.4 4.6 8.3 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Rubredoxin_2 PF18073.1 EIM87362.1 - 1.1 9.1 7.3 2 8.2 0.6 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF1610 PF07754.11 EIM87362.1 - 7 6.7 7.0 23 5.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) AIM5 PF17050.5 EIM87364.1 - 0.00031 21.5 0.0 0.00039 21.2 0.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Thaumatin PF00314.17 EIM87365.1 - 5.4e-71 238.6 6.0 6.1e-71 238.5 6.0 1.0 1 0 0 1 1 1 1 Thaumatin family BRO1 PF03097.18 EIM87366.1 - 3.4e-118 394.8 0.1 8.4e-118 393.5 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EIM87366.1 - 2e-54 184.9 13.4 3.6e-54 184.1 13.4 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF4795 PF16043.5 EIM87366.1 - 2.6 7.6 11.4 3.8 7.1 8.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF5127 PF17168.4 EIM87367.1 - 7.4e-77 258.2 5.9 7.4e-77 258.2 5.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM87367.1 - 8e-50 168.9 0.7 1.5e-49 168.0 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM87367.1 - 1.8e-40 139.1 0.2 1.8e-40 139.1 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM87367.1 - 0.015 14.8 0.1 0.04 13.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Serglycin PF04360.12 EIM87367.1 - 0.14 12.1 4.7 0.12 12.3 1.7 2.4 2 0 0 2 2 2 0 Serglycin DUF948 PF06103.11 EIM87368.1 - 0.0022 18.2 0.2 1.6 9.0 0.0 3.0 1 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) DUF759 PF05537.11 EIM87368.1 - 0.016 14.1 1.3 0.039 12.9 0.1 1.8 1 1 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) EspB PF05802.11 EIM87368.1 - 0.035 14.1 0.2 0.09 12.8 0.1 1.7 1 1 0 1 1 1 0 Enterobacterial EspB protein SesA PF17107.5 EIM87368.1 - 0.23 11.7 1.8 0.69 10.1 0.5 2.1 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases F-box-like PF12937.7 EIM87369.1 - 0.00057 19.7 0.7 0.0014 18.5 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM87369.1 - 0.01 15.7 0.4 0.029 14.2 0.4 1.8 1 0 0 1 1 1 0 F-box domain DUF5127 PF17168.4 EIM87370.1 - 7.1e-66 222.2 1.1 7.1e-66 222.2 1.1 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM87370.1 - 2.2e-51 173.9 0.3 4.4e-51 173.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM87370.1 - 1.4e-33 116.7 4.6 1.1e-32 113.8 1.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM87370.1 - 3.4e-06 26.5 0.1 1.6e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) bZIP_1 PF00170.21 EIM87371.1 - 0.00067 19.7 2.1 0.002 18.1 2.1 1.8 1 0 0 1 1 1 1 bZIP transcription factor JAKMIP_CC3 PF16034.5 EIM87371.1 - 0.0061 16.5 0.5 0.0061 16.5 0.5 1.7 2 0 0 2 2 2 1 JAKMIP CC3 domain TolA_bind_tri PF16331.5 EIM87371.1 - 0.016 15.3 1.4 0.05 13.7 0.5 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation MbeD_MobD PF04899.12 EIM87371.1 - 0.028 14.6 1.8 0.95 9.6 0.2 2.7 2 1 0 2 2 2 0 MbeD/MobD like ADIP PF11559.8 EIM87371.1 - 0.03 14.4 3.8 0.63 10.1 0.5 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EIM87371.1 - 0.031 14.0 0.6 0.091 12.5 0.6 1.8 1 0 0 1 1 1 0 Septum formation initiator CASP_C PF08172.12 EIM87371.1 - 0.032 13.6 0.6 0.032 13.6 0.6 1.6 2 0 0 2 2 2 0 CASP C terminal NRBF2 PF08961.10 EIM87371.1 - 0.038 13.6 0.5 0.038 13.6 0.5 1.7 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 EIM87371.1 - 0.041 14.3 1.2 0.041 14.3 1.2 2.3 3 0 0 3 3 2 0 Cell division protein ZapB Uso1_p115_C PF04871.13 EIM87371.1 - 0.077 13.4 0.6 0.077 13.4 0.6 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 EIM87371.1 - 0.11 13.1 4.6 1.1 9.9 1.8 2.7 2 1 0 2 2 2 0 Initiation control protein YabA TSNAXIP1_N PF15739.5 EIM87371.1 - 0.18 12.2 3.3 0.17 12.3 0.5 2.0 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus FlaC_arch PF05377.11 EIM87371.1 - 0.21 12.0 7.9 0.16 12.4 2.2 3.0 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 EIM87371.1 - 0.26 11.1 5.8 0.069 13.0 2.0 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 EIM87371.1 - 0.39 11.1 2.9 1.1 9.6 1.0 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family CENP-Q PF13094.6 EIM87371.1 - 0.52 10.5 6.3 3.4 7.8 2.1 2.8 2 2 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.11 EIM87371.1 - 0.56 10.5 3.6 0.42 10.9 0.4 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 EIM87371.1 - 0.82 9.8 8.1 0.2 11.7 4.3 2.1 2 0 0 2 2 1 0 Basic region leucine zipper Csm1_N PF18504.1 EIM87371.1 - 0.83 10.0 4.6 0.77 10.1 1.6 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain Tropomyosin_1 PF12718.7 EIM87371.1 - 1.2 9.3 8.0 2.9 8.0 4.0 2.6 2 1 0 2 2 2 0 Tropomyosin like APG6_N PF17675.1 EIM87371.1 - 1.7 9.2 6.5 0.38 11.3 2.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EIM87371.1 - 2.6 8.1 9.2 1.1 9.2 4.2 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 EIM87371.1 - 4.2 7.7 6.9 0.29 11.4 0.6 2.4 3 0 0 3 3 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 EIM87371.1 - 9.5 6.3 6.5 6.6 6.8 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PikAIV_N PF18605.1 EIM87371.1 - 9.8 5.9 8.6 2.7 7.6 1.7 2.6 2 1 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ndc1_Nup PF09531.10 EIM87372.1 - 0.00088 18.1 0.7 0.0011 17.7 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin protein Ndc1-Nup TMEM171 PF15471.6 EIM87373.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 F-box-like PF12937.7 EIM87374.1 - 2.6e-09 36.8 0.1 7e-09 35.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM87374.1 - 0.0098 16.3 6.5 1.4 9.4 0.1 5.0 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.33 EIM87374.1 - 0.12 12.2 2.3 0.38 10.7 0.7 2.6 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.6 EIM87374.1 - 0.4 10.5 5.4 0.33 10.7 0.1 3.4 4 0 0 4 4 4 0 Leucine rich repeat DUF5127 PF17168.4 EIM87375.1 - 3.9e-74 249.3 6.3 7.2e-74 248.4 6.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM87375.1 - 3.7e-49 166.7 2.2 3.7e-49 166.7 2.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM87375.1 - 1.1e-34 120.3 0.8 3.7e-34 118.6 0.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM87375.1 - 0.00018 21.0 0.0 0.00046 19.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) SKG6 PF08693.10 EIM87375.1 - 0.00022 20.5 0.3 0.00045 19.6 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glyco_hydro_28 PF00295.17 EIM87376.1 - 1.6e-41 142.4 5.7 6.7e-41 140.4 5.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Sds3 PF08598.11 EIM87377.1 - 1.2e-21 77.7 1.9 1.2e-21 77.7 1.9 2.7 3 0 0 3 3 3 1 Sds3-like DUF4743 PF15916.5 EIM87378.1 - 5e-10 39.4 0.0 7.4e-06 25.9 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4743) NUDIX PF00293.28 EIM87378.1 - 4e-05 23.7 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Yip1 PF04893.17 EIM87379.1 - 2.1e-08 34.1 21.2 2.7e-08 33.7 21.2 1.2 1 0 0 1 1 1 1 Yip1 domain Ost5 PF05251.12 EIM87379.1 - 0.42 10.9 10.4 0.16 12.3 4.7 2.4 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 ThiF PF00899.21 EIM87380.1 - 1e-41 142.9 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EIM87380.1 - 0.001 19.3 0.7 0.0062 16.8 0.7 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EIM87380.1 - 0.011 16.2 0.1 0.03 14.8 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EIM87380.1 - 0.052 12.8 0.2 0.078 12.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EIM87380.1 - 0.098 11.9 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EIM87380.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peroxidase_2 PF01328.17 EIM87381.1 - 8.3e-48 163.4 0.0 1.1e-47 163.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 TauD PF02668.16 EIM87382.1 - 3.2e-48 164.9 0.2 4.2e-48 164.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.25 EIM87384.1 - 1.8e-73 247.2 0.0 2.2e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87384.1 - 2.2e-32 112.4 0.0 3.2e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM87384.1 - 4.2e-05 23.0 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIM87384.1 - 0.00037 19.4 0.0 0.00057 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EIM87384.1 - 0.0004 19.8 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM87384.1 - 0.0025 17.8 0.0 0.009 16.0 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family FERM_N PF09379.10 EIM87384.1 - 0.023 14.6 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 FERM N-terminal domain Acetyltransf_1 PF00583.25 EIM87385.1 - 2.2e-05 24.6 0.0 4.3e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM87385.1 - 9e-05 22.8 0.2 0.00079 19.8 0.2 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM87385.1 - 0.00061 19.7 0.0 0.0026 17.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EIM87385.1 - 0.0018 18.0 0.3 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EIM87385.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NAD_binding_6 PF08030.12 EIM87386.1 - 4.2e-37 127.7 0.0 6.9e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIM87386.1 - 3.6e-24 84.9 0.0 9.1e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EIM87386.1 - 6.3e-18 65.1 7.5 6.3e-18 65.1 7.5 2.7 2 1 0 3 3 3 1 Ferric reductase like transmembrane component Pam17 PF08566.10 EIM87386.1 - 0.12 12.2 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 NAD_binding_1 PF00175.21 EIM87386.1 - 0.2 12.3 0.1 1 10.0 0.0 2.3 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DLH PF01738.18 EIM87387.1 - 1.1e-22 80.7 0.0 1.6e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EIM87387.1 - 0.0029 17.3 0.0 0.086 12.5 0.0 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM87387.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 EIM87387.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aldo_ket_red PF00248.21 EIM87388.1 - 1.8e-48 165.3 0.0 2e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 EIM87389.1 - 3.7e-21 75.4 0.0 7.4e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM87389.1 - 0.00044 20.3 14.4 0.00078 19.5 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TB2_DP1_HVA22 PF03134.19 EIM87390.1 - 3.4e-05 23.7 1.0 8.7e-05 22.4 1.0 1.7 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Goodbye PF17109.5 EIM87391.1 - 9.1e-22 77.8 0.0 2.2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EIM87391.1 - 4.4e-12 46.2 0.1 1.2e-11 44.8 0.1 1.8 1 0 0 1 1 1 1 NACHT domain BrkDBD PF09607.10 EIM87391.1 - 0.098 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain DUF1664 PF07889.12 EIM87391.1 - 0.2 11.7 0.3 1.5 8.9 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 EIM87392.1 - 1.9e-25 89.2 6.0 3.7e-14 53.1 1.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM87392.1 - 2.6e-19 69.3 3.1 4.4e-08 33.5 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIM87392.1 - 4.9e-17 61.8 0.2 1.3e-06 28.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EIM87392.1 - 1.8e-11 43.9 6.1 0.00026 21.3 0.2 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EIM87392.1 - 3.9e-11 42.2 0.3 0.019 15.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat DUF892 PF05974.12 EIM87392.1 - 0.00012 22.1 0.9 4.1 7.4 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF892) Spidroin_MaSp PF11260.8 EIM87392.1 - 0.0029 17.9 0.4 9.3 6.6 0.0 3.1 3 0 0 3 3 3 1 Major ampullate spidroin 1 and 2 eIF-5a PF01287.20 EIM87392.1 - 0.01 15.9 0.0 6.4 6.9 0.0 2.8 1 1 2 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold CholecysA-Rec_N PF09193.10 EIM87392.1 - 0.013 15.5 2.0 46 4.1 0.0 4.1 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal DUF1521 PF07481.11 EIM87392.1 - 0.043 13.8 2.8 0.25 11.3 2.3 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1521) TNV_CP PF03898.13 EIM87392.1 - 0.057 12.7 2.7 1.8 7.8 0.4 2.5 1 1 2 3 3 3 0 Satellite tobacco necrosis virus coat protein DUF1843 PF08898.10 EIM87392.1 - 0.11 13.0 4.2 9.5 6.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF4625 PF15418.6 EIM87392.1 - 0.18 12.1 0.3 9 6.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) P19Arf_N PF07392.12 EIM87392.1 - 0.22 12.0 0.3 59 4.2 0.0 3.0 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Fer2_4 PF13510.6 EIM87392.1 - 0.39 10.8 4.2 1.7 8.7 0.7 3.0 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TB2_DP1_HVA22 PF03134.19 EIM87393.1 - 3.6e-28 97.3 2.6 5.5e-28 96.7 2.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Gpr1_Fun34_YaaH PF01184.19 EIM87394.1 - 1.1e-31 110.1 21.4 1.4e-31 109.8 21.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_hydro_43 PF04616.14 EIM87395.1 - 1.9e-14 53.7 2.0 3.4e-14 52.8 2.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CW_binding_1 PF01473.20 EIM87395.1 - 0.029 14.7 0.3 0.12 12.7 0.3 2.2 1 0 0 1 1 1 0 Putative cell wall binding repeat BAH PF01426.18 EIM87398.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 BAH domain Toxin_8 PF07365.12 EIM87398.1 - 0.11 12.8 0.7 0.36 11.1 0.7 1.9 1 0 0 1 1 1 0 Alpha conotoxin precursor zf_CopZ PF18423.1 EIM87398.1 - 0.3 11.1 6.0 0.069 13.1 1.1 2.4 2 1 0 2 2 2 0 Zinc binding domain PHD PF00628.29 EIM87398.1 - 0.68 9.9 9.6 1.7 8.6 5.0 3.0 3 0 0 3 3 3 0 PHD-finger PHD PF00628.29 EIM87399.1 - 1.5e-05 24.8 2.4 0.00017 21.4 1.3 2.4 2 0 0 2 2 2 1 PHD-finger BAH PF01426.18 EIM87399.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 BAH domain zf-HC5HC2H PF13771.6 EIM87399.1 - 0.044 14.1 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Thaumatin PF00314.17 EIM87400.1 - 6.5e-71 238.4 12.2 7.8e-71 238.1 12.2 1.1 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.21 EIM87400.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Exo_endo_phos PF03372.23 EIM87401.1 - 5.6e-07 29.3 0.6 8.5e-07 28.7 0.6 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Velvet PF11754.8 EIM87402.1 - 1.1e-46 159.8 0.0 1.1e-46 159.8 0.0 1.8 2 0 0 2 2 2 1 Velvet factor APO_RNA-bind PF05634.11 EIM87402.1 - 0.27 10.6 0.9 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 APO RNA-binding Glucan_synthase PF02364.15 EIM87404.1 - 0 1319.5 0.0 0 1319.1 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EIM87404.1 - 1.3e-42 145.2 0.2 3.7e-42 143.7 0.2 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MULE PF10551.9 EIM87406.1 - 9.2e-11 42.0 0.0 4.2e-10 39.9 0.0 2.2 2 1 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 EIM87406.1 - 2.9e-06 26.8 0.3 6.3e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger VIR_N PF15912.5 EIM87407.1 - 1.9 8.0 7.3 2.8 7.5 7.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Terminase_4 PF05119.12 EIM87409.1 - 0.034 14.6 0.0 0.098 13.1 0.0 1.6 1 1 1 2 2 2 0 Phage terminase, small subunit Phage_min_cap2 PF06152.11 EIM87409.1 - 0.24 10.3 0.0 0.26 10.1 0.0 1.0 1 0 0 1 1 1 0 Phage minor capsid protein 2 DEAD PF00270.29 EIM87410.1 - 1.3e-10 41.3 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fungal_trans PF04082.18 EIM87411.1 - 1.2e-15 57.2 0.0 2.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM87411.1 - 0.005 16.9 14.2 0.005 16.9 14.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3182 PF11379.8 EIM87412.1 - 0.031 13.3 0.1 0.05 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Pkinase PF00069.25 EIM87413.1 - 0.00012 21.6 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EIM87413.1 - 0.00089 18.9 0.1 0.0011 18.6 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EIM87413.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EIM87413.1 - 0.019 14.3 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GST_N_3 PF13417.6 EIM87414.1 - 4.2e-12 46.3 0.0 8.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM87414.1 - 8.8e-09 35.5 0.0 2e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM87414.1 - 8.2e-05 22.5 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM87414.1 - 0.0001 22.5 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM87414.1 - 0.0024 18.0 0.0 0.0057 16.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM87414.1 - 0.026 15.3 0.0 0.13 13.0 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 EIM87414.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Vps26 PF03643.15 EIM87416.1 - 3.5e-130 432.9 2.3 4e-130 432.7 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EIM87416.1 - 0.0012 18.9 0.5 0.97 9.5 0.1 3.2 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EIM87416.1 - 0.023 15.2 0.1 0.91 10.0 0.1 2.9 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain AAA_5 PF07728.14 EIM87417.1 - 4.3e-64 214.7 0.0 5.5e-28 97.7 0.0 3.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIM87417.1 - 0.0026 18.2 0.3 7.2 7.0 0.0 4.2 3 1 1 4 4 4 1 AAA ATPase domain Histone_HNS PF00816.21 EIM87417.1 - 0.013 16.3 5.4 0.96 10.3 0.1 3.4 3 0 0 3 3 3 0 H-NS histone family vWA-TerF-like PF10138.9 EIM87417.1 - 0.095 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus Roc PF08477.13 EIM87417.1 - 0.1 12.8 0.0 0.83 9.9 0.0 2.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_28 PF00295.17 EIM87418.1 - 9.8e-63 212.2 17.5 1.2e-62 211.8 17.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EIM87418.1 - 5.3e-11 42.6 28.3 9.7e-10 38.5 17.5 3.0 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.13 EIM87418.1 - 5e-06 26.0 6.7 1.1e-05 24.9 6.7 1.7 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EIM87418.1 - 3.1e-05 23.4 8.3 6.1e-05 22.5 8.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) DUF2013 PF09431.10 EIM87419.1 - 1.1e-53 181.2 0.1 2.2e-53 180.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Rcd1 PF04078.13 EIM87419.1 - 0.028 13.7 0.3 0.047 13.0 0.3 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like VIT1 PF01988.19 EIM87420.1 - 2.6e-63 213.8 6.2 3.1e-63 213.5 6.2 1.1 1 0 0 1 1 1 1 VIT family SLATT_fungal PF18142.1 EIM87420.1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Acetyltransf_9 PF13527.7 EIM87421.1 - 4.3e-05 23.6 0.0 0.0026 17.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM87421.1 - 0.0018 18.7 0.0 0.0028 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM87421.1 - 0.0087 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_8 PF08022.12 EIM87422.1 - 0.048 13.8 0.1 0.086 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD-binding domain APOC4 PF15119.6 EIM87423.1 - 0.026 14.8 0.1 0.058 13.7 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein C4 FAD_binding_8 PF08022.12 EIM87423.1 - 0.11 12.5 0.1 0.42 10.7 0.1 1.8 1 1 1 2 2 2 0 FAD-binding domain Plus-3 PF03126.18 EIM87424.1 - 7e-36 123.1 0.0 3.1e-34 117.8 0.0 2.9 2 0 0 2 2 2 1 Plus-3 domain Sof1 PF04158.14 EIM87425.1 - 6.2e-28 96.9 11.3 1.4e-27 95.7 11.3 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EIM87425.1 - 7e-21 74.2 12.7 3.1e-07 31.0 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM87425.1 - 2.5e-06 27.7 0.6 0.49 10.7 0.1 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM87425.1 - 0.00086 19.2 0.0 0.023 14.6 0.0 2.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BAH PF01426.18 EIM87426.1 - 5.4e-15 55.3 1.0 6.3e-07 29.3 0.1 2.3 2 0 0 2 2 2 2 BAH domain PHD PF00628.29 EIM87426.1 - 0.079 12.9 2.4 0.19 11.7 1.0 2.3 2 0 0 2 2 2 0 PHD-finger BTB PF00651.31 EIM87427.1 - 6.2e-05 23.2 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CLN3 PF02487.17 EIM87428.1 - 8.3e-131 436.7 0.1 9.7e-131 436.5 0.1 1.0 1 0 0 1 1 1 1 CLN3 protein PNP_UDP_1 PF01048.20 EIM87429.1 - 6.8e-37 127.0 0.4 9.2e-37 126.5 0.4 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily PKD_3 PF16820.5 EIM87430.1 - 0.086 12.6 0.1 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 PKD-like domain Iso_dh PF00180.20 EIM87431.1 - 1.2e-72 244.9 0.0 1.5e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short PF00106.25 EIM87432.1 - 5.4e-37 127.1 0.0 6.6e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87432.1 - 1e-32 113.6 0.0 1.5e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87432.1 - 3.2e-11 43.5 0.1 4.6e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EIM87433.1 - 4.3e-35 121.0 0.0 5.4e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87433.1 - 2.1e-31 109.3 0.0 2.8e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87433.1 - 1e-10 41.9 0.0 1.5e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EIM87433.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 EIM87434.1 - 2.6e-39 134.7 0.0 3.6e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87434.1 - 5.6e-35 121.0 0.0 7.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87434.1 - 3.2e-12 46.7 0.1 4.9e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 KR domain PilS PF08805.11 EIM87434.1 - 0.043 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 PilS N terminal Pkinase PF00069.25 EIM87435.1 - 2.9e-12 46.5 0.0 4.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TPR_12 PF13424.6 EIM87436.1 - 9.3e-06 25.8 3.6 0.0012 19.1 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM87436.1 - 0.00032 20.4 10.8 0.64 9.9 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM87436.1 - 0.00076 19.4 13.0 0.14 12.4 2.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM87436.1 - 0.061 14.2 4.5 1.6 9.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM87436.1 - 0.12 12.1 3.2 1.6 8.5 0.4 2.6 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 EIM87436.1 - 0.43 11.3 6.9 0.42 11.3 1.5 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EIM87436.1 - 0.83 9.8 3.6 0.62 10.2 0.4 2.2 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EIM87436.1 - 1.5 9.2 7.6 12 6.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM87436.1 - 2.5 8.9 6.9 9.2 7.1 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Dynamin_N PF00350.23 EIM87437.1 - 1.5e-13 51.1 0.0 6.8e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EIM87437.1 - 5.6e-07 29.6 0.0 0.00028 21.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM87437.1 - 2.8e-05 24.1 0.2 0.0011 18.9 0.0 3.3 5 0 0 5 5 5 1 RsgA GTPase ABC_tran PF00005.27 EIM87437.1 - 0.0011 19.5 0.0 0.0097 16.4 0.0 2.6 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 EIM87437.1 - 0.0061 17.0 0.1 0.032 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EIM87437.1 - 0.018 15.3 0.0 0.073 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 EIM87437.1 - 0.061 12.4 0.0 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF815 PF05673.13 EIM87437.1 - 0.099 11.8 0.6 0.57 9.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) T2SSE PF00437.20 EIM87437.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EIM87437.1 - 0.14 12.5 0.0 0.71 10.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 EIM87437.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein UPF0561 PF10573.9 EIM87437.1 - 0.5 10.5 5.4 1.3 9.2 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 DUF883 PF05957.13 EIM87437.1 - 3.3 8.4 5.6 16 6.2 0.3 4.5 5 0 0 5 5 4 0 Bacterial protein of unknown function (DUF883) FAM199X PF15814.5 EIM87438.1 - 0.024 13.7 1.1 0.039 13.0 1.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X SAP PF02037.27 EIM87439.1 - 4.1e-05 23.2 1.0 8.3e-05 22.2 0.4 1.9 2 0 0 2 2 2 1 SAP domain GMC_oxred_N PF00732.19 EIM87440.1 - 2.9e-64 217.3 0.0 3.6e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87440.1 - 1.2e-34 119.9 0.0 1.9e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EIM87440.1 - 0.00022 21.0 0.3 0.00041 20.0 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM87440.1 - 0.00026 21.2 0.1 0.0006 20.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM87440.1 - 0.00029 20.1 0.0 0.0096 15.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EIM87440.1 - 0.00087 18.4 0.2 0.0022 17.1 0.2 1.7 1 1 1 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIM87440.1 - 0.03 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM87440.1 - 0.044 12.5 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EIM87440.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM87440.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family BTB PF00651.31 EIM87441.1 - 0.001 19.3 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain PhnA_Zn_Ribbon PF08274.12 EIM87441.1 - 0.0024 17.8 0.2 1.9 8.5 0.0 2.6 2 0 0 2 2 2 2 PhnA Zinc-Ribbon Peptidase_C48 PF02902.19 EIM87442.1 - 9.5e-08 32.1 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPX PF03105.19 EIM87443.1 - 0.47 10.3 7.0 0.61 9.9 7.0 1.2 1 0 0 1 1 1 0 SPX domain ABC_membrane PF00664.23 EIM87444.1 - 3.1e-101 338.6 24.3 1.7e-53 182.0 11.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM87444.1 - 8e-68 227.2 0.0 3.4e-33 115.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EIM87444.1 - 6.2e-14 52.0 1.0 0.00016 21.2 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EIM87444.1 - 1.9e-07 30.3 0.1 0.0018 17.2 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EIM87444.1 - 4.9e-07 30.3 1.7 0.0069 16.8 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EIM87444.1 - 6.6e-07 29.0 0.1 0.011 15.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EIM87444.1 - 6.6e-07 29.4 0.0 0.14 12.0 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EIM87444.1 - 1.4e-06 28.6 1.3 0.097 12.9 0.1 4.3 4 1 0 4 4 4 2 AAA domain AAA_15 PF13175.6 EIM87444.1 - 2.5e-06 27.5 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM87444.1 - 2.3e-05 24.4 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EIM87444.1 - 2.5e-05 23.6 0.0 0.033 13.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.6 EIM87444.1 - 8e-05 23.2 0.2 0.23 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EIM87444.1 - 0.00017 21.2 0.1 0.85 9.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 EIM87444.1 - 0.00017 20.9 0.0 0.35 10.0 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 EIM87444.1 - 0.00024 21.5 0.3 4 7.9 0.1 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM87444.1 - 0.0011 18.9 0.0 1.4 8.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EIM87444.1 - 0.0025 18.4 0.0 3.8 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EIM87444.1 - 0.0026 17.3 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 EIM87444.1 - 0.0063 16.7 0.1 6.4 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EIM87444.1 - 0.0068 16.7 0.0 2.1 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EIM87444.1 - 0.0086 16.3 1.8 7.4 6.9 0.2 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EIM87444.1 - 0.0096 15.6 5.1 1.1 9.0 0.1 3.9 3 2 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EIM87444.1 - 0.011 14.9 0.0 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 EIM87444.1 - 0.016 15.3 0.1 10 6.2 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 EIM87444.1 - 0.018 15.0 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain PRK PF00485.18 EIM87444.1 - 0.02 14.6 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EIM87444.1 - 0.021 15.2 0.1 3.2 8.2 0.0 3.2 3 0 0 3 3 2 0 RNA helicase DUF815 PF05673.13 EIM87444.1 - 0.03 13.5 0.0 7.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 EIM87444.1 - 0.051 13.3 0.0 8.8 6.0 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 EIM87444.1 - 0.061 12.7 0.0 13 5.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 EIM87444.1 - 0.092 13.2 0.1 27 5.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EIM87444.1 - 0.11 12.4 0.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.12 EIM87444.1 - 0.13 12.2 0.2 23 4.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF2685 PF10886.8 EIM87444.1 - 0.16 12.2 0.0 0.7 10.1 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) AAA_24 PF13479.6 EIM87444.1 - 0.16 11.7 0.0 22 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAO PF01266.24 EIM87445.1 - 4.1e-57 194.4 1.0 5.2e-57 194.0 1.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM87445.1 - 0.00019 20.8 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM87445.1 - 0.0033 17.6 0.2 0.0033 17.6 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EIM87445.1 - 0.0055 17.2 0.1 0.08 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM87445.1 - 0.016 14.5 0.2 0.054 12.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 EIM87445.1 - 0.059 13.0 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EIM87445.1 - 0.13 11.0 0.0 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 EIM87445.1 - 0.16 12.2 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GIY-YIG PF01541.24 EIM87447.1 - 6.8e-11 42.3 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EIM87447.1 - 0.00075 19.6 2.0 0.0013 18.8 2.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EIM87447.1 - 0.0057 17.0 5.0 0.0098 16.2 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.11 EIM87447.1 - 0.13 12.6 3.4 0.43 10.9 3.1 2.1 1 1 0 1 1 1 0 RING-like domain Tmpp129 PF10272.9 EIM87447.1 - 0.65 9.2 1.7 0.98 8.6 1.7 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor adh_short_C2 PF13561.6 EIM87448.1 - 1.5e-47 162.2 0.1 2.3e-47 161.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM87448.1 - 1.7e-42 145.1 0.4 4.7e-42 143.7 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM87448.1 - 4.4e-09 36.5 0.0 6.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM87448.1 - 0.0084 15.3 0.1 0.012 14.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EIM87448.1 - 0.035 14.0 0.2 0.066 13.1 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EIM87448.1 - 0.051 13.0 0.0 2.5 7.5 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EIM87448.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DEAD PF00270.29 EIM87449.1 - 4.8e-48 163.2 0.0 9.5e-48 162.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM87449.1 - 3.3e-23 82.1 0.1 2.7e-22 79.2 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EIM87449.1 - 3.3e-19 68.9 0.0 7.6e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EIM87449.1 - 2.9e-05 24.1 0.0 0.00012 22.1 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EIM87449.1 - 0.00085 18.6 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase NAPRTase_N PF17767.1 EIM87449.1 - 0.012 16.0 0.6 0.19 12.1 0.1 2.4 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Helicase_C_2 PF13307.6 EIM87449.1 - 0.16 12.2 3.4 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 Helicase C-terminal domain CMS1 PF14617.6 EIM87449.1 - 0.96 8.7 8.5 8.8 5.6 0.0 3.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SUR7 PF06687.12 EIM87450.1 - 2e-17 63.6 17.3 2e-17 63.6 17.3 1.7 1 1 1 2 2 2 2 SUR7/PalI family PAG PF15347.6 EIM87450.1 - 0.067 12.2 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Pyr_redox_2 PF07992.14 EIM87450.1 - 0.12 11.6 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RCR PF12273.8 EIM87450.1 - 0.24 12.1 0.1 0.24 12.1 0.1 2.2 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 EIM87450.1 - 6.5 7.7 0.0 6.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Dynamin_N PF00350.23 EIM87451.1 - 2.4e-06 27.7 0.0 1.6e-05 25.0 0.0 2.4 2 1 0 2 2 2 1 Dynamin family Med9 PF07544.13 EIM87451.1 - 0.044 13.9 1.3 0.19 11.9 1.3 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 YGGT PF02325.17 EIM87453.1 - 0.012 16.0 0.5 0.02 15.3 0.5 1.3 1 0 0 1 1 1 0 YGGT family DUF2208 PF09973.9 EIM87453.1 - 0.014 15.1 1.2 0.02 14.6 1.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF2207 PF09972.9 EIM87453.1 - 0.057 12.2 0.1 0.076 11.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.8 EIM87453.1 - 0.062 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function ODV-E18 PF10717.9 EIM87453.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Sigma_reg_N PF13800.6 EIM87453.1 - 0.31 11.3 1.9 0.4 11.0 0.4 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CBM_1 PF00734.18 EIM87454.1 - 8.1e-11 41.7 11.6 8.1e-11 41.7 11.6 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain RVP_2 PF08284.11 EIM87455.1 - 0.094 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease adh_short PF00106.25 EIM87456.1 - 8.9e-36 123.2 0.0 1.1e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87456.1 - 6.1e-32 111.1 0.0 8.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87456.1 - 8.3e-11 42.1 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EIM87457.1 - 6.5e-36 123.6 0.0 7.9e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87457.1 - 1.2e-31 110.1 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87457.1 - 8.4e-12 45.4 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EIM87457.1 - 0.07 12.9 0.7 0.16 11.8 0.3 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 EIM87457.1 - 0.088 12.3 0.0 1 8.8 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase_fungal PF17667.1 EIM87458.1 - 4.5e-06 25.7 0.1 7.9e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Importin_rep_4 PF18808.1 EIM87458.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Importin repeat Pkinase_fungal PF17667.1 EIM87459.1 - 1.4e-30 106.5 0.0 2.6e-19 69.3 0.0 3.1 1 1 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EIM87459.1 - 4.4e-05 23.5 0.9 0.00049 20.1 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM87459.1 - 0.0032 16.9 0.0 0.0063 15.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain SOG2 PF10428.9 EIM87460.1 - 1.7 7.8 9.6 1.8 7.7 9.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short PF00106.25 EIM87461.1 - 7.1e-37 126.8 0.0 9.6e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87461.1 - 2.1e-32 112.6 0.0 3e-32 112.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87461.1 - 6.5e-11 42.5 0.0 9.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 KR domain IBR PF01485.21 EIM87462.1 - 1.5e-13 50.7 26.9 1.5e-07 31.5 7.1 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EIM87462.1 - 1.6e-06 28.2 5.5 1.6e-06 28.2 5.5 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EIM87462.1 - 1.8e-06 27.9 5.1 1.8e-06 27.9 5.1 3.3 3 1 0 3 3 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIM87462.1 - 2.7e-05 23.9 2.4 2.7e-05 23.9 2.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM87462.1 - 5.7e-05 22.9 4.2 5.7e-05 22.9 4.2 4.3 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 EIM87462.1 - 6.8e-05 22.8 4.6 0.00014 21.8 4.6 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 EIM87462.1 - 0.00012 21.8 1.9 0.00012 21.8 1.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM87462.1 - 0.00024 21.4 3.9 0.00024 21.4 3.9 3.8 3 1 1 4 4 2 1 Ring finger domain zf-CCCH PF00642.24 EIM87462.1 - 0.0012 18.7 0.9 0.003 17.4 0.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 EIM87462.1 - 0.0051 16.7 4.3 0.0051 16.7 4.3 3.8 2 1 1 3 3 1 1 zinc-RING finger domain zf-CCCH_4 PF18044.1 EIM87462.1 - 0.011 15.5 0.5 0.029 14.2 0.5 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger RRM_1 PF00076.22 EIM87462.1 - 0.024 14.5 0.0 13 5.7 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 EIM87462.1 - 0.046 14.2 0.7 0.18 12.3 0.7 2.1 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FlpD PF02662.16 EIM87462.1 - 0.059 13.4 1.6 0.32 11.0 0.0 2.8 1 1 1 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit WH1 PF00568.23 EIM87463.1 - 2.8e-11 43.4 0.2 1.7e-10 40.8 0.2 2.0 1 1 0 1 1 1 1 WH1 domain PBD PF00786.28 EIM87463.1 - 0.0059 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pyr_redox_2 PF07992.14 EIM87464.1 - 4.8e-44 150.8 0.0 5.8e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM87464.1 - 2.2e-11 44.2 0.0 1.7e-09 38.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM87464.1 - 0.027 13.7 0.0 2.1 7.5 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Bac_rhodopsin PF01036.18 EIM87465.1 - 9.6e-34 116.9 16.9 1.2e-33 116.5 16.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2953 PF11167.8 EIM87465.1 - 3.4 7.8 6.1 3 8.0 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF4131 PF13567.6 EIM87465.1 - 9.2 5.9 14.4 8.8 5.9 1.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) SYF2 PF08231.12 EIM87466.1 - 3.9e-60 202.8 18.9 3.9e-60 202.8 18.9 1.5 2 0 0 2 2 2 1 SYF2 splicing factor Prominin PF05478.11 EIM87466.1 - 0.22 9.4 0.9 0.25 9.3 0.9 1.1 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 EIM87466.1 - 0.36 11.0 4.6 0.091 12.9 1.1 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family 5_nucleotid PF05761.14 EIM87466.1 - 0.93 8.3 11.1 6.4 5.6 11.1 1.9 1 1 0 1 1 1 0 5' nucleotidase family Kinesin_assoc PF16183.5 EIM87466.1 - 1.6 8.9 7.1 0.77 9.9 3.9 1.9 2 0 0 2 2 2 0 Kinesin-associated ALS2CR8 PF15299.6 EIM87466.1 - 3.6 7.4 8.5 0.51 10.2 4.8 1.4 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 MFS_1 PF07690.16 EIM87467.1 - 1.3e-31 109.9 37.4 1.9e-31 109.3 37.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ORC_WH_C PF18137.1 EIM87468.1 - 1.5e-43 148.2 0.7 2.8e-43 147.3 0.7 1.5 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 EIM87468.1 - 2.5e-30 105.7 0.0 8.7e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF4611 PF15387.6 EIM87468.1 - 2.8 8.2 6.1 4.8 7.5 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Smg4_UPF3 PF03467.15 EIM87469.1 - 1.8e-50 171.3 0.5 1.8e-50 171.3 0.5 2.2 2 0 0 2 2 2 1 Smg-4/UPF3 family DUF4121 PF13497.6 EIM87469.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) F-box-like PF12937.7 EIM87470.1 - 1.1e-07 31.6 5.7 1.6e-06 27.9 5.7 2.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM87470.1 - 0.24 11.3 5.7 0.53 10.2 0.0 3.4 3 0 0 3 3 3 0 F-box domain CAP_N PF01213.19 EIM87471.1 - 0.08 12.4 0.5 0.1 12.1 0.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fungal_trans PF04082.18 EIM87472.1 - 9.2e-40 136.3 0.0 1.4e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM87472.1 - 5.6e-07 29.6 13.0 9.2e-07 28.9 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mre11_DNA_bind PF04152.14 EIM87473.1 - 4.9e-46 157.1 0.0 4.9e-46 157.1 0.0 2.6 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EIM87473.1 - 7.4e-15 56.0 0.2 1.2e-14 55.3 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM87473.1 - 6.2e-06 26.5 0.0 7e-05 23.1 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF572 PF04502.13 EIM87473.1 - 0.67 9.5 16.2 1 8.9 16.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CENP-B_dimeris PF09026.10 EIM87473.1 - 0.75 10.2 12.6 1.6 9.1 1.1 3.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Stm1_N PF09598.10 EIM87473.1 - 0.89 10.5 27.1 0.85 10.5 10.6 2.9 2 0 0 2 2 2 0 Stm1 SAPS PF04499.15 EIM87473.1 - 1.2 7.8 8.0 2.2 7.0 8.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TPT PF03151.16 EIM87474.1 - 1.7e-12 47.3 17.9 1.9e-12 47.2 17.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EIM87474.1 - 8.1e-05 22.8 35.9 0.0025 18.0 13.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family NCOA_u2 PF16665.5 EIM87475.1 - 0.038 14.3 8.8 2.8 8.3 7.6 2.3 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein PAPS_reduct PF01507.19 EIM87476.1 - 1.1e-27 97.2 0.0 1.6e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Tetraspanin PF00335.20 EIM87477.1 - 0.16 11.7 3.3 0.42 10.3 3.3 1.8 1 0 0 1 1 1 0 Tetraspanin family MFS_1 PF07690.16 EIM87478.1 - 2.8e-39 135.0 21.0 2.8e-39 135.0 21.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EIM87478.1 - 0.024 13.5 0.0 0.024 13.5 0.0 2.6 2 1 0 2 2 2 0 MFS_1 like family Peptidase_M20 PF01546.28 EIM87479.1 - 8.7e-31 107.2 0.0 1.6e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM87479.1 - 3.2e-12 46.3 0.0 5.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM87479.1 - 0.037 13.7 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.28 EIM87480.1 - 6.4e-36 124.0 0.0 8.8e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM87480.1 - 2.4e-10 40.3 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ADC PF06314.11 EIM87481.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) adh_short PF00106.25 EIM87482.1 - 6.8e-34 117.0 0.0 9.2e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87482.1 - 5.7e-32 111.1 0.0 8.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87482.1 - 4e-09 36.6 0.0 6.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Actin PF00022.19 EIM87482.1 - 0.12 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Actin adh_short PF00106.25 EIM87483.1 - 1.7e-25 89.6 0.2 5.2e-17 62.0 0.1 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87483.1 - 1e-19 71.0 0.3 2e-13 50.4 0.8 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87483.1 - 0.017 15.0 0.2 0.032 14.2 0.2 1.4 1 0 0 1 1 1 0 KR domain SUZ PF12752.7 EIM87484.1 - 6e-12 46.1 0.6 6e-12 46.1 0.6 3.6 4 1 0 4 4 4 2 SUZ domain Ribosomal_S17 PF00366.20 EIM87485.1 - 7.5e-21 74.0 2.8 8.8e-21 73.8 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Cob_adeno_trans PF01923.18 EIM87486.1 - 0.02 15.0 2.1 0.04 14.0 1.5 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Phage_holin_3_6 PF07332.11 EIM87486.1 - 0.084 12.9 1.2 0.18 11.8 1.2 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Epimerase PF01370.21 EIM87487.1 - 3.8e-52 177.2 0.0 5.6e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM87487.1 - 6.5e-15 55.4 0.4 7.2e-14 51.9 0.4 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EIM87487.1 - 7.1e-06 25.3 0.0 1.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EIM87487.1 - 7e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EIM87487.1 - 0.00024 20.4 0.1 0.016 14.3 0.1 2.8 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein HgmA PF04209.13 EIM87487.1 - 0.071 11.8 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase GDP_Man_Dehyd PF16363.5 EIM87488.1 - 2.9e-156 520.0 0.0 3.3e-156 519.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EIM87488.1 - 2.1e-72 243.5 0.0 2.8e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EIM87488.1 - 0.00013 21.2 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIM87488.1 - 0.002 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EIM87488.1 - 0.0064 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DUF4446 PF14584.6 EIM87489.1 - 0.0064 16.5 2.1 4.9 7.1 0.0 3.2 2 1 2 4 4 4 2 Protein of unknown function (DUF4446) Tropomyosin_1 PF12718.7 EIM87489.1 - 0.07 13.3 0.3 0.07 13.3 0.3 2.5 2 1 0 2 2 2 0 Tropomyosin like PKcGMP_CC PF16808.5 EIM87489.1 - 0.091 12.6 2.7 0.76 9.7 0.7 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 EIM87489.1 - 0.48 11.1 11.7 0.44 11.2 0.7 3.5 2 1 1 3 3 3 0 SlyX AAA_19 PF13245.6 EIM87489.1 - 2.8 8.3 4.8 2.2 8.6 2.2 2.0 2 0 0 2 2 2 0 AAA domain BPL_LplA_LipB PF03099.19 EIM87490.1 - 5.4e-22 78.1 0.0 9.6e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 EIM87490.1 - 1.4e-16 60.5 0.0 4.8e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal ABC_transp_aux PF09822.9 EIM87490.1 - 0.035 13.6 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system BPL_C PF02237.17 EIM87490.1 - 0.041 13.8 0.5 0.58 10.1 0.5 2.5 1 1 0 1 1 1 0 Biotin protein ligase C terminal domain Peptidase_S24 PF00717.23 EIM87491.1 - 1.2e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Aldo_ket_red PF00248.21 EIM87492.1 - 2.8e-33 115.4 0.0 5.9e-25 88.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family F-box-like PF12937.7 EIM87493.1 - 9.6e-09 35.0 0.7 2.4e-07 30.6 0.2 2.5 2 0 0 2 2 2 1 F-box-like Fer2_BFD PF04324.15 EIM87493.1 - 0.046 14.1 0.1 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain LRR_4 PF12799.7 EIM87493.1 - 0.071 13.6 5.4 19 5.9 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Mt_ATP_synt PF15704.5 EIM87493.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit Peptidase_S24 PF00717.23 EIM87494.1 - 5.9e-07 29.4 0.0 9.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Ribosomal_S30 PF04758.14 EIM87495.1 - 2.1e-24 85.5 6.8 3.1e-24 84.9 6.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 DUF4594 PF15266.6 EIM87495.1 - 0.063 13.6 4.2 0.071 13.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) Pterin_bind PF00809.22 EIM87496.1 - 2.7e-56 191.0 0.0 6.2e-56 189.8 0.0 1.6 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EIM87496.1 - 4.4e-33 114.1 0.0 7.7e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EIM87496.1 - 2.5e-16 60.2 0.1 5.8e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Dihydroneopterin aldolase TPR_16 PF13432.6 EIM87497.1 - 1.1e-10 42.0 0.0 0.0043 17.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM87497.1 - 2.8e-10 39.5 0.1 0.18 12.0 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIM87497.1 - 8.1e-10 38.7 3.9 0.00055 20.5 0.0 4.9 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM87497.1 - 2e-09 37.8 2.0 0.0022 18.5 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM87497.1 - 9.6e-08 31.5 0.0 0.037 13.9 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM87497.1 - 2.4e-07 30.4 0.0 0.49 10.8 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM87497.1 - 2e-06 28.1 0.4 0.37 11.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EIM87497.1 - 7.6e-06 26.0 0.1 0.15 12.3 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM87497.1 - 0.00011 21.9 0.1 0.071 12.8 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 EIM87497.1 - 0.00026 20.8 1.4 14 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM87497.1 - 0.027 14.8 1.9 47 4.4 0.1 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat CotJB PF12652.7 EIM87497.1 - 0.083 13.1 0.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 CotJB protein TPR_17 PF13431.6 EIM87497.1 - 0.093 13.1 0.3 8.5 7.0 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat GPI-anchored PF10342.9 EIM87498.1 - 2.7e-07 31.2 0.4 2.7e-07 31.2 0.4 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.9 EIM87498.1 - 5.7 5.4 11.9 7.5 5.0 11.9 1.1 1 0 0 1 1 1 0 Macoilin family GPI-anchored PF10342.9 EIM87499.1 - 2.2e-11 44.4 1.0 2.2e-11 44.4 1.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DXP_reductoisom PF02670.16 EIM87499.1 - 0.0008 20.1 1.3 0.0014 19.4 1.3 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sporozoite_P67 PF05642.11 EIM87499.1 - 0.37 8.8 10.5 0.56 8.2 10.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 EIM87499.1 - 4.2 5.5 12.4 4.5 5.4 12.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 EIM87499.1 - 5 5.6 5.9 5.5 5.4 5.9 1.0 1 0 0 1 1 1 0 Macoilin family Aldo_ket_red PF00248.21 EIM87501.1 - 1.6e-69 234.3 0.0 2e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ANAPC4_WD40 PF12894.7 EIM87502.1 - 1.5e-17 63.6 7.6 1.7e-05 25.0 0.1 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM87502.1 - 2.2e-17 63.1 16.8 2.5e-06 28.1 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.11 EIM87502.1 - 5.8e-08 32.8 0.2 0.00044 20.2 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EIM87502.1 - 3.3e-05 23.0 0.6 0.42 9.5 0.0 3.8 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NifZ PF04319.13 EIM87502.1 - 0.0011 18.8 0.5 0.0011 18.8 0.5 2.0 2 0 0 2 2 2 1 NifZ domain DJ-1_PfpI PF01965.24 EIM87503.1 - 2e-11 44.0 0.0 3.7e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EIM87503.1 - 6e-05 22.8 0.1 0.00073 19.3 0.1 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like 4HBT PF03061.22 EIM87504.1 - 1.2e-07 32.0 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily GMC_oxred_N PF00732.19 EIM87505.1 - 1.6e-50 172.2 0.0 2.5e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87505.1 - 1.3e-28 100.4 0.0 2.6e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM87505.1 - 4e-06 26.2 1.5 3e-05 23.3 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EIM87505.1 - 6.7e-06 25.4 0.8 0.0022 17.1 0.1 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EIM87505.1 - 8.5e-06 25.2 0.0 2.7e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM87505.1 - 1.4e-05 24.9 0.7 9.4e-05 22.1 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM87505.1 - 2.9e-05 24.2 1.1 6.8e-05 23.0 0.5 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM87505.1 - 3.7e-05 22.9 0.1 6.7e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EIM87505.1 - 5.3e-05 22.6 0.4 0.00095 18.5 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM87505.1 - 0.0012 18.2 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EIM87505.1 - 0.0031 16.3 0.0 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EIM87505.1 - 0.0056 16.1 1.1 0.012 15.0 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM87505.1 - 0.0065 17.0 0.1 0.025 15.1 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase PDDEXK_7 PF04411.12 EIM87505.1 - 0.031 14.2 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Thi4 PF01946.17 EIM87505.1 - 0.039 13.2 0.0 0.096 11.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EIM87505.1 - 0.044 13.8 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EIM87505.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 EIM87505.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 EIM87505.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fer2 PF00111.27 EIM87506.1 - 6e-11 42.2 0.1 8.5e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-MYND PF01753.18 EIM87508.1 - 4.9e-07 29.7 15.7 9.3e-07 28.8 15.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM87508.1 - 0.99 9.8 8.2 2 8.8 8.2 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EIM87509.1 - 6.7e-07 29.3 16.6 1.2e-06 28.4 16.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM87509.1 - 0.47 10.8 10.3 0.9 9.9 10.3 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Adap_comp_sub PF00928.21 EIM87510.1 - 1.5e-92 309.8 0.2 2.8e-92 308.8 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIM87510.1 - 7.6e-06 25.9 0.3 1.3e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EIM87510.1 - 0.0027 17.2 0.1 0.0051 16.3 0.1 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Spo7 PF03907.13 EIM87511.1 - 2.8e-35 121.8 0.0 5.6e-35 120.8 0.0 1.4 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 EIM87511.1 - 0.18 12.2 0.1 0.4 11.1 0.1 1.6 1 1 0 1 1 1 0 Transmembrane protein 188 DUF4230 PF14014.6 EIM87512.1 - 0.015 15.6 0.9 0.18 12.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) Ino80_Iec3 PF14612.6 EIM87512.1 - 0.37 11.4 2.9 0.39 11.3 0.1 2.3 2 1 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling p450 PF00067.22 EIM87513.1 - 9.9e-68 229.0 0.0 2.2e-67 227.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF1688 PF07958.11 EIM87514.1 - 5.9e-176 585.3 0.0 6.6e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PHP PF02811.19 EIM87516.1 - 4.7e-10 40.0 0.1 1.1e-09 38.8 0.1 1.6 1 1 0 1 1 1 1 PHP domain Glyco_hydro_28 PF00295.17 EIM87517.1 - 1.4e-26 93.4 9.6 1.1e-20 74.0 1.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 MFS_2 PF13347.6 EIM87519.1 - 6.9e-08 31.5 9.0 6.9e-08 31.5 9.0 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein ETF_QO PF05187.13 EIM87520.1 - 1.5e-30 105.4 1.8 8.6e-24 83.7 0.2 2.4 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 EIM87520.1 - 2.6e-08 34.0 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM87520.1 - 5.7e-06 26.1 1.1 9.7e-05 22.1 0.9 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM87520.1 - 8.6e-06 25.1 0.7 0.00018 20.7 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM87520.1 - 3.9e-05 23.0 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM87520.1 - 6.3e-05 22.3 0.0 0.0009 18.5 0.2 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EIM87520.1 - 0.00039 20.4 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EIM87520.1 - 0.00042 19.7 0.2 0.00042 19.7 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIM87520.1 - 0.0005 18.9 0.6 0.00077 18.3 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM87520.1 - 0.00067 19.0 0.7 0.0011 18.3 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM87520.1 - 0.0016 17.5 0.2 0.0026 16.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EIM87520.1 - 0.016 15.8 0.0 4.3 8.0 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM87520.1 - 0.017 14.5 0.3 0.029 13.7 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIM87520.1 - 0.025 13.5 0.4 0.04 12.8 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DUF5548 PF17702.1 EIM87520.1 - 0.1 12.3 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5548) GIDA PF01134.22 EIM87520.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-MYND PF01753.18 EIM87521.1 - 1.7e-07 31.2 18.5 2.8e-07 30.5 18.5 1.3 1 0 0 1 1 1 1 MYND finger ADH_zinc_N PF00107.26 EIM87523.1 - 1.7e-11 44.2 0.0 5.4e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM87523.1 - 6e-09 35.8 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM87523.1 - 0.02 16.0 0.0 0.039 15.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM87524.1 - 2.8e-25 88.3 5.3 4.6e-25 87.6 5.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM87524.1 - 1.4e-13 51.0 0.1 2.3e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIM87524.1 - 0.0024 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 EIM87524.1 - 0.016 15.5 0.2 0.078 13.3 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EIM87524.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EIM87525.1 - 7.6e-35 120.3 0.0 1.2e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM87525.1 - 8.2e-35 120.2 0.0 2.4e-34 118.6 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM87525.1 - 1.5e-12 47.5 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM87525.1 - 7.5e-08 32.6 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 EIM87525.1 - 0.0037 17.7 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EIM87525.1 - 0.0074 16.2 0.0 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EIM87525.1 - 0.011 14.9 0.0 0.089 11.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein UL20 PF17582.2 EIM87525.1 - 0.02 14.2 0.0 0.076 12.3 0.0 1.8 2 0 0 2 2 2 0 Cytomegalovirus UL20 DXP_reductoisom PF02670.16 EIM87525.1 - 0.12 13.1 0.1 0.34 11.6 0.1 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MFS_1 PF07690.16 EIM87526.1 - 2e-33 115.8 27.2 2e-33 115.8 27.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EIM87526.1 - 7.1e-10 38.7 4.3 7.1e-10 38.7 4.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MoCF_biosynth PF00994.24 EIM87527.1 - 5.7e-32 110.4 0.0 8.7e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF773 PF05600.12 EIM87528.1 - 0.078 11.7 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Ribosomal_S18 PF01084.20 EIM87528.1 - 0.13 12.5 0.1 0.39 11.0 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein S18 AAA_11 PF13086.6 EIM87529.1 - 1.7e-66 224.7 1.5 3.7e-66 223.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EIM87529.1 - 2.6e-58 197.0 0.0 4.2e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM87529.1 - 1.1e-10 41.6 0.0 4.7e-06 26.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EIM87529.1 - 1.1e-10 41.7 0.1 0.02 14.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EIM87529.1 - 6.8e-10 39.4 0.0 7.9e-09 36.0 0.0 2.6 2 2 0 2 2 2 1 AAA domain ResIII PF04851.15 EIM87529.1 - 2e-05 24.7 0.0 0.00033 20.7 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EIM87529.1 - 3.6e-05 23.2 0.3 0.2 10.9 0.0 3.2 4 0 0 4 4 4 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EIM87529.1 - 6e-05 22.7 0.0 0.0081 15.7 0.0 2.5 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EIM87529.1 - 0.00019 21.7 0.1 0.0026 18.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EIM87529.1 - 0.00042 20.1 0.1 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 EIM87529.1 - 0.00092 18.7 0.0 1 8.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_23 PF13476.6 EIM87529.1 - 0.0028 18.2 0.0 0.019 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EIM87529.1 - 0.0043 16.8 0.1 0.15 11.8 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA PF00004.29 EIM87529.1 - 0.0097 16.3 0.2 0.056 13.9 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM87529.1 - 0.012 16.0 0.0 0.039 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EIM87529.1 - 0.014 15.1 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EIM87529.1 - 0.078 12.1 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.22 EIM87529.1 - 0.1 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase CCSAP PF15748.5 EIM87529.1 - 0.42 10.8 7.3 1.1 9.4 7.3 1.6 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GATase_6 PF13522.6 EIM87530.1 - 1.2e-11 44.9 0.0 2.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EIM87530.1 - 1.2e-05 24.4 0.1 2.9e-05 23.1 0.0 1.7 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_7 PF13537.6 EIM87530.1 - 0.028 14.3 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain KH_5 PF13184.6 EIM87530.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 NusA-like KH domain MCM PF00493.23 EIM87531.1 - 5.5e-98 326.5 0.0 8.4e-98 325.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIM87531.1 - 1.4e-37 128.4 0.4 2.9e-37 127.3 0.4 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIM87531.1 - 5.7e-28 97.2 1.4 1.1e-27 96.3 1.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIM87531.1 - 2.2e-16 60.3 0.4 8.6e-16 58.4 0.0 2.2 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 EIM87531.1 - 1.3e-09 38.2 0.0 3.4e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EIM87531.1 - 1.7e-07 30.8 0.0 7.9e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EIM87531.1 - 0.00011 22.0 0.0 0.0018 18.1 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIM87531.1 - 0.00028 20.6 0.0 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 EIM87531.1 - 0.0025 18.2 0.9 0.044 14.2 0.9 2.9 1 1 0 1 1 1 1 AAA ATPase domain RNA_pol_Rpc34 PF05158.12 EIM87532.1 - 4.9e-77 259.6 4.7 3.2e-66 224.0 0.8 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit Promethin PF16015.5 EIM87533.1 - 0.0002 21.3 26.6 0.00029 20.7 26.6 1.2 1 0 0 1 1 1 1 Promethin Tetraspanin PF00335.20 EIM87533.1 - 0.035 13.8 2.8 0.041 13.6 2.8 1.2 1 0 0 1 1 1 0 Tetraspanin family DDDD PF10161.9 EIM87533.1 - 1.3 8.8 3.5 3.8 7.3 3.5 1.8 1 0 0 1 1 1 0 Putative mitochondrial precursor protein DUF3487 PF11990.8 EIM87533.1 - 6.2 6.7 9.5 11 6.0 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) CBM_1 PF00734.18 EIM87534.1 - 1.2e-11 44.3 17.1 1.2e-11 44.3 17.1 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Chorion_3 PF05387.11 EIM87534.1 - 0.055 13.1 3.0 0.077 12.6 3.0 1.2 1 0 0 1 1 1 0 Chorion family 3 C2 PF00168.30 EIM87535.1 - 8.8e-28 96.6 0.0 2.7e-16 59.7 0.0 3.1 3 0 0 3 3 3 2 C2 domain PAP2 PF01569.21 EIM87535.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 PAP2 superfamily HLH PF00010.26 EIM87538.1 - 2.4e-12 46.6 0.2 6.5e-12 45.2 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 EIM87538.1 - 5.3 7.4 11.2 1.2 9.5 6.8 2.1 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 PH_10 PF15411.6 EIM87539.1 - 0.1 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain HAUS4 PF14735.6 EIM87540.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 HetR_C PF18460.1 EIM87540.1 - 0.13 12.2 2.9 4.4 7.3 0.8 3.0 2 1 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Tannase PF07519.11 EIM87541.1 - 1.2e-90 304.7 0.0 1.4e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EIM87541.1 - 0.0034 16.7 0.0 0.72 9.1 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 ATPase_2 PF01637.18 EIM87542.1 - 7.7e-12 45.6 0.0 8.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EIM87542.1 - 0.00032 21.1 0.2 0.0012 19.3 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain RNA12 PF10443.9 EIM87542.1 - 0.0013 17.5 0.0 0.029 13.1 0.0 2.2 2 0 0 2 2 2 1 RNA12 protein AAA_14 PF13173.6 EIM87542.1 - 0.0055 16.7 0.0 4.1 7.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EIM87542.1 - 0.011 16.2 0.0 7.7 7.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2587 PF10759.9 EIM87542.1 - 0.075 12.6 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) AAA_22 PF13401.6 EIM87542.1 - 0.15 12.3 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ribonucleas_3_3 PF14622.6 EIM87543.1 - 2.7e-07 30.8 0.0 4.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIM87543.1 - 8.1e-06 26.4 0.0 3e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Piwi PF02171.17 EIM87544.1 - 2.9e-85 286.1 0.0 3.9e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EIM87544.1 - 5.4e-24 85.4 0.0 1.1e-23 84.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EIM87544.1 - 3.1e-20 71.6 0.3 7.7e-20 70.3 0.3 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EIM87544.1 - 5e-16 58.7 0.0 8.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EIM87544.1 - 5.5e-10 39.4 0.0 2e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 EIM87544.1 - 0.00099 19.3 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ApbA_C PF08546.11 EIM87545.1 - 6.6e-21 74.8 0.0 6.6e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EIM87545.1 - 2.9e-16 59.5 0.0 4.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Peptidase_M10 PF00413.24 EIM87545.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Matrixin DHHA2 PF02833.14 EIM87547.1 - 9.5e-28 97.2 1.2 2.7e-27 95.7 0.6 2.0 2 1 0 2 2 2 1 DHHA2 domain DHH PF01368.20 EIM87547.1 - 5.6e-14 52.2 0.0 9.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 DHH family Urm1 PF09138.11 EIM87548.1 - 4.9e-35 119.8 0.0 5.7e-34 116.4 0.0 1.9 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EIM87548.1 - 1.7e-05 25.3 0.0 2.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family ThiS-like PF14453.6 EIM87548.1 - 0.046 13.8 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 ThiS-like ubiquitin Complex1_LYR PF05347.15 EIM87549.1 - 1.4e-14 53.9 0.4 1.7e-14 53.6 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EIM87549.1 - 0.018 15.8 0.1 0.02 15.7 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like MFS_1 PF07690.16 EIM87550.1 - 3.1e-39 134.9 28.2 3.1e-39 134.9 28.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM87550.1 - 4.5e-14 52.2 1.3 4.5e-14 52.2 1.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter PQ-loop PF04193.14 EIM87551.1 - 6.9e-17 61.0 19.7 2.5e-09 36.8 0.7 3.8 4 0 0 4 4 4 2 PQ loop repeat Wzy_C PF04932.15 EIM87551.1 - 2.1 7.9 0.0 2.1 7.9 0.0 2.9 2 1 0 2 2 2 0 O-Antigen ligase Myosin_tail_1 PF01576.19 EIM87552.1 - 0.0025 15.7 23.6 0.005 14.7 23.6 1.5 1 0 0 1 1 1 1 Myosin tail GAS PF13851.6 EIM87552.1 - 0.0048 16.3 6.7 0.0048 16.3 6.7 3.4 2 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding Tup_N PF08581.10 EIM87552.1 - 0.018 15.3 0.5 0.018 15.3 0.5 3.3 3 1 1 4 4 4 0 Tup N-terminal HALZ PF02183.18 EIM87552.1 - 0.091 13.0 0.6 0.091 13.0 0.6 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Phage_GP20 PF06810.11 EIM87552.1 - 0.78 9.5 7.5 2.2 8.1 5.9 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 Macoilin PF09726.9 EIM87552.1 - 3.6 6.0 30.0 1 7.8 21.9 2.4 1 1 1 2 2 2 0 Macoilin family AIP3 PF03915.13 EIM87552.1 - 4.4 6.3 15.1 9.9 5.1 9.8 2.2 1 1 1 2 2 2 0 Actin interacting protein 3 betaPIX_CC PF16523.5 EIM87552.1 - 5.8 6.8 13.5 1 9.2 0.8 3.9 4 0 0 4 4 4 0 betaPIX coiled coil Fez1 PF06818.15 EIM87552.1 - 7.5 6.9 32.3 0.028 14.9 6.7 3.1 2 1 1 3 3 3 0 Fez1 TPR_14 PF13428.6 EIM87553.1 - 1.8e-26 90.6 35.3 1e-05 25.9 0.2 13.0 5 2 10 15 15 14 8 Tetratricopeptide repeat HAT PF02184.16 EIM87553.1 - 1.8e-21 75.8 64.4 5.4e-07 29.5 4.9 14.6 15 1 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EIM87553.1 - 5.4e-20 71.7 6.1 0.00023 21.6 0.2 7.7 6 2 3 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EIM87553.1 - 2.6e-17 61.5 11.2 0.067 13.3 0.0 9.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EIM87553.1 - 2.1e-13 50.6 21.1 0.0017 18.9 0.2 7.6 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EIM87553.1 - 3e-09 36.6 6.4 0.00014 22.0 0.4 5.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM87553.1 - 3.7e-09 36.1 6.5 0.77 10.1 0.1 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM87553.1 - 1.2e-08 34.4 0.1 0.21 11.5 0.2 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM87553.1 - 1.9e-07 31.3 7.3 0.62 10.4 0.0 6.8 6 1 0 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 EIM87553.1 - 2.2e-07 30.6 6.8 0.0008 18.9 0.6 4.1 4 0 0 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 EIM87553.1 - 2.4e-07 30.8 12.9 0.18 12.0 0.0 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 EIM87553.1 - 4.6e-06 26.0 23.9 0.13 11.5 4.1 5.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM87553.1 - 1.4e-05 24.7 2.6 6 6.6 0.0 5.7 5 0 0 5 5 5 1 TPR repeat TPR_6 PF13174.6 EIM87553.1 - 1.7e-05 25.1 15.0 16 6.4 0.1 8.9 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM87553.1 - 0.00042 20.2 17.4 2.4 8.4 0.0 8.2 10 0 0 10 10 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EIM87553.1 - 0.00086 19.3 23.6 0.059 13.4 1.0 7.2 6 2 1 7 7 6 1 Mad3/BUB1 homology region 1 Fis1_TPR_C PF14853.6 EIM87553.1 - 0.0034 17.4 3.1 5.8 7.1 0.0 5.1 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EIM87553.1 - 0.0038 17.4 2.7 3.8 7.8 0.2 4.2 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 U3_assoc_6 PF08640.11 EIM87553.1 - 0.048 13.7 0.6 0.048 13.7 0.6 6.7 5 3 3 8 8 8 0 U3 small nucleolar RNA-associated protein 6 DUF3836 PF12930.7 EIM87553.1 - 0.3 10.9 3.7 2.7 7.8 0.9 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF3836) TGT PF01702.18 EIM87554.1 - 2.8e-34 118.8 0.0 2.3e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase AMP-binding PF00501.28 EIM87555.1 - 3.5e-32 111.6 0.0 2.3e-31 108.8 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EIM87555.1 - 3e-30 105.2 0.0 6.6e-30 104.1 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EIM87555.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM87555.1 - 2.1e-06 28.0 0.0 4.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EIM87555.1 - 0.012 14.6 0.0 0.028 13.4 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ PF00226.31 EIM87556.1 - 4.1e-21 74.9 0.6 8.2e-21 73.9 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Aldo_ket_red PF00248.21 EIM87557.1 - 2e-71 240.6 0.1 2.2e-71 240.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM87558.1 - 2.2e-73 247.1 0.0 2.5e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM87559.1 - 3.7e-56 190.5 0.0 4.4e-28 98.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family PAF-AH_p_II PF03403.13 EIM87560.1 - 2.2e-47 161.4 0.0 9.5e-32 109.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EIM87560.1 - 3.7e-11 42.4 0.0 9.3e-07 28.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 EIM87560.1 - 6e-09 35.3 0.0 2.8e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.8 EIM87560.1 - 3.8e-06 26.3 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM87560.1 - 0.0051 17.4 0.1 0.0051 17.4 0.1 2.1 2 2 1 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EIM87560.1 - 0.0084 16.3 0.0 0.038 14.1 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.20 EIM87560.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EIM87560.1 - 0.018 14.9 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 EIM87560.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase BORCS8 PF10167.9 EIM87560.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Peptidase_S9 PF00326.21 EIM87560.1 - 0.14 11.6 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aldo_ket_red PF00248.21 EIM87561.1 - 9e-74 248.3 0.0 1e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_18 PF15024.6 EIM87562.1 - 7.6e-11 41.3 0.0 1.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Aldo_ket_red PF00248.21 EIM87563.1 - 2.3e-70 237.1 0.0 3.1e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S8 PF00410.19 EIM87564.1 - 8.7e-24 83.9 0.1 1.2e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 EIM87565.1 - 8.4e-59 196.8 0.2 1.1e-58 196.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Lactonase PF10282.9 EIM87566.1 - 7.3e-10 38.6 0.0 2.1e-07 30.6 0.0 2.8 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller SNRNP27 PF08648.12 EIM87567.1 - 0.059 13.4 0.3 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins CTP_transf_1 PF01148.20 EIM87568.1 - 0.0022 17.8 2.2 0.0051 16.6 2.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase family DNA_pol_A_exo1 PF01612.20 EIM87569.1 - 6.4e-19 68.3 0.0 1.2e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Whi5 PF08528.11 EIM87569.1 - 5.6e-07 29.0 0.7 1.2e-06 27.9 0.7 1.6 1 0 0 1 1 1 1 Whi5 like DnaJ PF00226.31 EIM87570.1 - 3.5e-18 65.5 0.4 1.2e-17 63.8 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain UQ_con PF00179.26 EIM87571.1 - 1.1e-49 167.7 0.0 1.2e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIM87571.1 - 0.00072 19.3 0.0 0.00093 18.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Alpha_L_fucos PF01120.17 EIM87573.1 - 4e-71 240.3 8.5 2.3e-54 185.2 7.9 2.1 1 1 1 2 2 2 2 Alpha-L-fucosidase Copper-fist PF00649.18 EIM87575.1 - 2.2e-23 81.5 1.6 2.2e-23 81.5 1.6 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain zinc-ribbons_6 PF07191.12 EIM87575.1 - 0.0093 15.9 2.9 0.013 15.4 2.9 1.3 1 0 0 1 1 1 1 zinc-ribbons VPS13 PF16908.5 EIM87577.1 - 1.6e-08 34.6 0.4 3.6e-08 33.5 0.4 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Sugarporin_N PF11471.8 EIM87577.1 - 0.05 13.6 1.3 0.29 11.1 0.9 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension zf-HC3 PF16827.5 EIM87577.1 - 0.061 13.5 1.2 0.24 11.6 1.2 2.0 1 0 0 1 1 1 0 zinc-finger WD40 PF00400.32 EIM87580.1 - 2.5e-22 78.8 6.8 0.00012 22.8 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM87580.1 - 0.0011 19.2 0.0 0.013 15.8 0.0 2.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EIM87580.1 - 0.015 13.9 0.1 0.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Aminotran_1_2 PF00155.21 EIM87581.1 - 3e-41 141.8 0.0 4.1e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myotoxins PF00819.17 EIM87581.1 - 0.082 13.2 0.0 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Myotoxin, crotamine Cys_Met_Meta_PP PF01053.20 EIM87581.1 - 0.22 10.0 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PDH PF02153.17 EIM87582.1 - 1.8e-16 59.9 0.0 2.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EIM87582.1 - 6e-05 23.3 0.0 9.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EIM87582.1 - 6.4e-05 23.5 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EIM87582.1 - 6.9e-05 22.9 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EIM87582.1 - 0.00023 20.8 0.0 0.0011 18.6 0.0 2.0 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EIM87582.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 EIM87582.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family DUF3879 PF12995.7 EIM87582.1 - 0.19 11.4 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) DIOX_N PF14226.6 EIM87583.1 - 1.1e-09 39.1 0.0 2.6e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM87583.1 - 1e-07 32.3 0.0 1.9e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dus PF01207.17 EIM87584.1 - 1.1e-49 169.2 0.0 1.6e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EIM87584.1 - 5.5e-08 32.5 7.1 0.0036 17.2 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EIM87584.1 - 1.3e-07 31.2 9.3 7.9e-05 22.4 0.7 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EIM87584.1 - 5.9e-05 23.0 9.4 0.032 14.3 0.6 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EIM87584.1 - 0.0022 18.7 0.6 0.15 12.8 0.1 2.5 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 EIM87584.1 - 0.79 10.3 6.5 0.23 12.0 0.3 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger FA_desaturase PF00487.24 EIM87585.1 - 8.8e-26 91.3 23.4 8.8e-26 91.3 23.4 1.4 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EIM87585.1 - 0.00018 21.7 0.1 0.00036 20.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_3 PF07859.13 EIM87586.1 - 3.3e-38 131.7 0.0 4.6e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM87586.1 - 0.0029 17.1 0.0 0.0055 16.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 EIM87586.1 - 0.032 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 EIM87586.1 - 0.063 12.2 0.0 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Peptidase_S15 PF02129.18 EIM87586.1 - 0.21 11.2 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EIM87587.1 - 2.5e-10 40.4 0.1 1.9e-09 37.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM87587.1 - 0.0029 16.9 0.0 0.0083 15.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EIM87587.1 - 0.031 13.0 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF775 PF05603.12 EIM87588.1 - 1.1e-56 191.6 0.0 1.2e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Abhydrolase_6 PF12697.7 EIM87589.1 - 0.00028 21.6 0.0 0.00041 21.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family HMGL-like PF00682.19 EIM87590.1 - 1.4e-47 162.5 0.0 1.7e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 HMGL-like DUF3368 PF11848.8 EIM87590.1 - 0.086 12.6 0.0 0.31 10.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) LVIVD PF08309.11 EIM87591.1 - 0.0062 15.8 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 LVIVD repeat LRR_4 PF12799.7 EIM87591.1 - 0.25 11.8 3.5 0.3 11.6 0.4 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EIM87591.1 - 0.63 10.2 1.9 88 3.6 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EIM87591.1 - 3.4 8.6 4.1 69 4.6 0.9 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Glyco_hydro_cc PF11790.8 EIM87592.1 - 3.3e-72 242.9 5.9 3.8e-72 242.7 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core F-box-like PF12937.7 EIM87593.1 - 0.00021 21.1 0.3 0.00021 21.1 0.3 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM87593.1 - 0.007 16.8 4.3 0.8 10.2 0.6 4.0 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EIM87593.1 - 0.21 11.7 4.4 5.8 7.2 0.1 4.2 6 0 0 6 6 6 0 Leucine Rich repeat DSBA PF01323.20 EIM87594.1 - 1e-19 71.1 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EIM87594.1 - 0.00092 19.4 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin SNF2_N PF00176.23 EIM87595.1 - 1.4e-68 231.2 0.1 3.1e-68 230.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM87595.1 - 9.5e-20 71.0 0.0 2.2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM87595.1 - 0.00025 21.1 0.0 0.00079 19.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIM87595.1 - 0.008 16.0 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EIM87595.1 - 0.037 13.2 0.1 0.072 12.3 0.1 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RNHCP PF12647.7 EIM87595.1 - 0.11 12.5 1.7 0.25 11.3 1.7 1.5 1 0 0 1 1 1 0 RNHCP domain HDA2-3 PF11496.8 EIM87595.1 - 0.8 8.8 3.3 0.39 9.9 0.1 2.0 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 EST1_DNA_bind PF10373.9 EIM87596.1 - 4.6e-28 98.5 0.0 3.4e-27 95.7 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EIM87596.1 - 9.5e-22 78.1 0.0 2.1e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 ArfGap PF01412.18 EIM87598.1 - 2e-35 121.4 0.2 3.4e-35 120.7 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5572 PF17733.1 EIM87599.1 - 8.9e-17 60.7 0.5 1.6e-16 59.8 0.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Aminotran_1_2 PF00155.21 EIM87600.1 - 1.9e-48 165.5 0.0 5.3e-46 157.5 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 EIM87600.1 - 0.00039 19.3 0.0 0.001 17.9 0.0 1.6 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 EIM87600.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Zn_Tnp_IS91 PF14319.6 EIM87601.1 - 0.73 9.9 7.3 6.9 6.8 7.3 2.1 1 1 0 1 1 1 0 Transposase zinc-binding domain adh_short PF00106.25 EIM87602.1 - 5.1e-35 120.7 0.0 6.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87602.1 - 1e-30 107.0 0.0 1.3e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87602.1 - 2e-09 37.6 0.0 3.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Aminotran_1_2 PF00155.21 EIM87603.1 - 7.8e-52 176.6 0.0 4.8e-44 151.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 EIM87603.1 - 0.00053 18.9 0.0 0.0009 18.1 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 EIM87603.1 - 0.001 18.4 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EIM87603.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V UDPG_MGDP_dh_N PF03721.14 EIM87604.1 - 4.6e-60 202.4 0.0 9.3e-60 201.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EIM87604.1 - 4.1e-33 113.9 0.2 1.2e-32 112.4 0.2 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EIM87604.1 - 7.4e-30 103.0 0.0 1.7e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 EIM87604.1 - 0.14 12.4 1.2 0.32 11.3 0.0 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DSPc PF00782.20 EIM87605.1 - 1.7e-31 108.8 0.0 2.2e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EIM87605.1 - 5.2e-05 23.5 0.0 9.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EIM87605.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Glu_syn_central PF04898.14 EIM87605.1 - 0.081 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Adenylsucc_synt PF00709.21 EIM87605.1 - 0.27 10.1 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Ras PF00071.22 EIM87606.1 - 4.2e-55 185.8 0.0 4.8e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM87606.1 - 9.2e-22 77.5 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM87606.1 - 1.7e-06 27.6 0.0 2.7e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIM87606.1 - 0.0029 17.0 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EIM87606.1 - 0.22 10.8 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Pro_CA PF00484.19 EIM87607.1 - 6.4e-43 146.8 0.1 7.6e-43 146.5 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Proteasome PF00227.26 EIM87611.1 - 3.1e-38 131.2 0.0 3.7e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MIG-14_Wnt-bd PF06664.12 EIM87612.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion MAP17 PF15807.5 EIM87612.1 - 0.16 12.2 0.1 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PsbJ PF01788.17 EIM87612.1 - 0.26 11.2 0.8 0.51 10.3 0.8 1.4 1 0 0 1 1 1 0 PsbJ SLD3 PF08639.10 EIM87613.1 - 1.1e-17 64.1 27.7 2.5e-16 59.6 27.7 2.0 1 1 0 1 1 1 1 DNA replication regulator SLD3 Peptidase_M16 PF00675.20 EIM87614.1 - 4.1e-23 82.0 0.1 7e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-C2H2 PF00096.26 EIM87616.1 - 1.7e-08 34.4 7.2 0.0017 18.7 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM87616.1 - 4.7e-06 27.0 5.9 0.016 16.0 0.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM87616.1 - 0.00011 22.5 4.8 0.034 14.6 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 EIM87616.1 - 0.012 16.0 2.2 0.023 15.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EIM87616.1 - 0.54 10.3 3.3 0.54 10.3 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EIM87616.1 - 0.61 10.1 5.9 8.7 6.4 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sec10 PF07393.11 EIM87617.1 - 5.3e-106 355.7 0.0 4.9e-77 260.0 0.0 2.0 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box PF00646.33 EIM87617.1 - 1.7e-05 24.6 0.2 3.5e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM87617.1 - 0.00046 20.0 0.1 0.00099 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Neuraminidase PF18413.1 EIM87617.1 - 3.9 7.1 5.7 0.75 9.4 1.8 1.7 2 0 0 2 2 2 0 Neuraminidase-like domain IDO PF01231.18 EIM87618.1 - 3.6e-107 358.8 0.0 4.2e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IMUP PF15761.5 EIM87618.1 - 7.5 7.3 8.2 9.6 6.9 0.7 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Cu-oxidase PF00394.22 EIM87621.1 - 4.2e-50 170.0 0.0 6.7e-46 156.3 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM87621.1 - 3.1e-39 133.8 1.1 5.7e-35 120.0 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM87621.1 - 5.7e-38 129.6 1.2 3.7e-37 127.0 0.2 2.8 4 1 0 4 4 4 1 Multicopper oxidase Sigma70_ECF PF07638.11 EIM87622.1 - 0.012 15.6 0.6 0.026 14.4 0.4 1.6 2 0 0 2 2 2 0 ECF sigma factor TMEM154 PF15102.6 EIM87622.1 - 2.4 8.1 10.6 1.2 9.0 0.3 3.2 1 1 1 2 2 2 0 TMEM154 protein family AdoMet_MTase PF07757.13 EIM87623.1 - 1.1e-33 115.9 0.0 6.2e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EIM87623.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PGI PF00342.19 EIM87624.1 - 9.3e-230 763.3 0.1 1.1e-229 763.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Fungal_trans PF04082.18 EIM87625.1 - 1.5e-21 76.7 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM87625.1 - 2.6e-05 24.2 12.9 4e-05 23.6 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_red PF03358.15 EIM87626.1 - 3.5e-08 33.3 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EIM87626.1 - 0.00013 21.7 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EIM87626.1 - 0.0066 16.7 0.2 0.034 14.4 0.2 2.1 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EIM87626.1 - 0.1 12.9 0.0 0.55 10.5 0.0 1.9 1 1 1 2 2 2 0 Flavodoxin domain PCI PF01399.27 EIM87627.1 - 0.17 12.4 0.0 0.59 10.7 0.0 1.9 1 1 0 1 1 1 0 PCI domain AA_permease_2 PF13520.6 EIM87629.1 - 3e-81 273.5 40.1 3.7e-81 273.1 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM87629.1 - 1.8e-15 56.5 34.6 2.8e-15 55.9 34.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM87630.1 - 4.6e-59 200.3 58.2 5.6e-59 200.1 58.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM87630.1 - 2e-12 46.5 50.1 9.5e-12 44.3 50.1 1.9 1 1 0 1 1 1 1 Amino acid permease Phage_holin_3_6 PF07332.11 EIM87630.1 - 0.02 14.9 0.2 0.02 14.9 0.2 4.9 4 2 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2715 PF10895.8 EIM87630.1 - 0.15 11.6 3.4 0.3 10.7 2.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) MIG-14_Wnt-bd PF06664.12 EIM87630.1 - 5.9 6.0 14.8 0.74 9.0 5.7 2.6 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DIOX_N PF14226.6 EIM87631.1 - 1.7e-14 54.6 0.0 3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM87631.1 - 1.4e-12 48.0 0.0 2.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIM87632.1 - 4.7e-15 56.4 0.0 8.7e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM87632.1 - 1.1e-12 48.3 0.0 2.9e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.10 EIM87633.1 - 0.04 13.3 12.5 0.059 12.7 12.5 1.2 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 EIM87633.1 - 0.1 11.4 4.3 0.54 9.1 5.7 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain CDC45 PF02724.14 EIM87633.1 - 6.9 4.8 9.9 8.6 4.5 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein AP3D1 PF06375.11 EIM87633.1 - 9.2 6.5 12.2 0.21 11.8 5.0 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 FAD_binding_3 PF01494.19 EIM87634.1 - 4.5e-66 223.5 0.0 5.6e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM87634.1 - 1.8e-08 34.3 0.7 0.00011 22.0 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM87634.1 - 5e-06 26.0 2.6 1.6 7.8 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM87634.1 - 8.1e-06 26.0 0.3 2.6e-05 24.3 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIM87634.1 - 8.6e-06 24.7 1.4 7.7e-05 21.6 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 EIM87634.1 - 1.1e-05 24.8 0.6 1.9e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EIM87634.1 - 8.1e-05 21.6 0.4 0.00014 20.9 0.4 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 EIM87634.1 - 8.3e-05 23.1 0.3 0.021 15.4 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM87634.1 - 0.00039 19.9 0.1 0.00061 19.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM87634.1 - 0.001 18.4 0.4 0.0048 16.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM87634.1 - 0.0016 17.6 0.3 0.0026 16.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EIM87634.1 - 0.016 15.6 0.1 0.055 13.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EIM87634.1 - 0.029 14.4 1.0 0.053 13.5 0.4 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EIM87634.1 - 0.07 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EIM87634.1 - 0.22 10.6 0.2 0.37 9.8 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Aldose_epim PF01263.20 EIM87635.1 - 4.3e-53 180.6 0.1 6e-41 140.7 0.1 2.1 2 0 0 2 2 2 2 Aldose 1-epimerase SspH PF08141.12 EIM87636.1 - 0.024 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein H family T2SSE_N PF05157.15 EIM87636.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain RRM_1 PF00076.22 EIM87638.1 - 3.9e-20 71.5 0.0 2.2e-12 46.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM87638.1 - 0.0019 18.3 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif PAM2 PF07145.15 EIM87638.1 - 0.048 13.3 0.4 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF1275 PF06912.11 EIM87639.1 - 1.3e-28 100.3 16.5 1.6e-28 100.0 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Peptidase_M24 PF00557.24 EIM87640.1 - 1.2e-10 41.5 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 JAB PF01398.21 EIM87641.1 - 1.5e-30 105.6 0.2 2.7e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EIM87641.1 - 4e-28 98.2 1.6 4e-28 98.2 1.6 1.7 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EIM87641.1 - 0.00053 19.8 0.0 0.00095 18.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain STAG PF08514.11 EIM87641.1 - 0.082 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 STAG domain Ribosomal_L18A PF01775.17 EIM87642.1 - 6.7e-54 181.1 0.7 8.4e-54 180.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A HisG_C PF08029.11 EIM87642.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain EAP30 PF04157.16 EIM87643.1 - 1e-58 198.4 0.0 1.2e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Leptin PF02024.15 EIM87643.1 - 0.073 12.8 0.1 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Leptin EF-hand_8 PF13833.6 EIM87643.1 - 0.22 11.4 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair GPI-anchored PF10342.9 EIM87644.1 - 5.3e-06 27.1 0.8 5.3e-06 27.1 0.8 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2163 PF09931.9 EIM87644.1 - 0.11 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) DUF3682 PF12446.8 EIM87644.1 - 0.88 10.1 14.8 1.6 9.2 14.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Amidase PF01425.21 EIM87646.1 - 4.8e-84 282.9 0.0 7.8e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 Amidase RPA_interact_N PF14766.6 EIM87647.1 - 0.099 12.3 2.1 0.26 10.9 2.1 1.7 1 0 0 1 1 1 0 Replication protein A interacting N-terminal HTH_23 PF13384.6 EIM87651.1 - 0.02 14.7 0.4 14 5.7 0.1 3.2 2 1 2 4 4 4 0 Homeodomain-like domain Strep_pep PF14404.6 EIM87651.1 - 1.8 8.9 6.8 6.5 7.1 0.3 3.4 1 1 2 3 3 3 0 Ribosomally synthesized peptide in Streptomyces species HTH_Tnp_ISL3 PF13542.6 EIM87651.1 - 2.4 7.7 8.8 8.6 5.9 0.1 4.2 4 1 1 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 Methyltr_RsmB-F PF01189.17 EIM87652.1 - 1.9e-36 125.6 0.0 7.2e-35 120.4 0.0 3.0 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EIM87652.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase RdRP PF05183.12 EIM87654.1 - 1.9e-164 548.6 0.0 2.4e-164 548.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Peptidase_A21 PF03566.13 EIM87654.1 - 0.11 10.7 0.5 0.19 10.0 0.5 1.3 1 0 0 1 1 1 0 Peptidase family A21 RdRP PF05183.12 EIM87655.1 - 4.1e-161 537.6 0.0 5.1e-161 537.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF4611 PF15387.6 EIM87655.1 - 0.18 12.0 3.5 0.42 10.8 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Astro_capsid_p PF12226.8 EIM87655.1 - 5.3 6.1 5.0 8.5 5.4 5.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RSB_motif PF16294.5 EIM87655.1 - 9.6 6.5 8.4 0.16 12.3 1.0 1.8 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif eIF3g PF12353.8 EIM87656.1 - 3.3e-44 150.3 0.9 5.4e-44 149.6 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EIM87656.1 - 2.8e-18 65.5 0.0 4.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIM87656.1 - 0.023 14.7 0.3 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 EIM87656.1 - 0.031 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OAM_alpha PF16552.5 EIM87656.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit Nup35_RRM_2 PF14605.6 EIM87656.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EIM87656.1 - 0.18 12.0 2.3 7.2 6.8 0.1 3.0 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter F-box-like PF12937.7 EIM87657.1 - 2.2e-10 40.2 0.7 5.5e-10 39.0 0.7 1.7 1 0 0 1 1 1 1 F-box-like Ammonium_transp PF00909.21 EIM87658.1 - 1.1e-116 389.9 28.8 1.2e-116 389.7 28.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Cys_Met_Meta_PP PF01053.20 EIM87659.1 - 2.2e-124 414.9 0.0 5.9e-97 324.6 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EIM87659.1 - 3.7e-05 23.1 0.0 5.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIM87659.1 - 0.0054 16.1 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OTT_1508_deam PF14441.6 EIM87660.1 - 6.6e-05 22.8 0.2 0.00013 21.9 0.2 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF3445 PF11927.8 EIM87662.1 - 7.5e-65 218.7 0.0 9.2e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.8 EIM87663.1 - 4.7e-58 196.5 0.0 6.3e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ring_hydroxyl_A PF00848.19 EIM87664.1 - 2.8e-24 86.3 7.8 2.4e-22 80.0 6.4 2.5 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EIM87664.1 - 1.1e-13 50.9 0.0 2.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF3242 PF11586.8 EIM87664.1 - 0.031 14.0 1.4 0.052 13.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) MFS_1 PF07690.16 EIM87665.1 - 3.9e-45 154.3 43.7 3.9e-45 154.3 43.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM87665.1 - 2.1e-16 59.9 39.0 8e-16 57.9 11.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EIM87665.1 - 4.5e-08 32.0 21.9 9e-08 31.0 21.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EIM87665.1 - 5.6 5.1 20.2 0.4 8.9 12.7 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HpcH_HpaI PF03328.14 EIM87667.1 - 3.3e-31 108.1 0.0 4.2e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF5107 PF17128.4 EIM87667.1 - 0.003 16.8 0.0 0.79 8.8 0.0 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF5107) PK PF00224.21 EIM87667.1 - 0.071 12.0 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Ferritin_2 PF13668.6 EIM87668.1 - 3e-44 150.5 2.8 4.8e-44 149.9 2.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain PI3K_1B_p101 PF10486.9 EIM87671.1 - 7.9 4.1 10.1 12 3.5 10.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Plavaka PF18759.1 EIM87672.1 - 1.8e-120 402.0 0.0 2.5e-120 401.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase CBM_20 PF00686.19 EIM87674.1 - 1.6e-33 114.5 0.3 3.6e-33 113.3 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 EIM87674.1 - 4.7e-15 56.0 0.0 1.5e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EIM87674.1 - 8e-10 39.1 0.1 2.7e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Bacillus_PapR PF05968.11 EIM87674.1 - 0.19 11.6 0.5 0.47 10.4 0.5 1.6 1 0 0 1 1 1 0 Bacillus PapR protein Citrate_bind PF16114.5 EIM87675.1 - 7.9e-90 299.1 0.2 2.1e-89 297.7 0.1 1.7 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EIM87675.1 - 6.8e-19 68.1 0.0 5.2e-16 58.7 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EIM87675.1 - 6.8e-15 55.2 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EIM87675.1 - 3e-14 53.5 0.0 7.1e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 EIM87675.1 - 5e-06 26.2 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EIM87675.1 - 1.2e-05 25.1 0.0 4.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain YacG PF03884.14 EIM87676.1 - 0.065 13.0 0.0 0.073 12.8 0.0 1.3 1 1 0 1 1 1 0 DNA gyrase inhibitor YacG Rad60-SLD_2 PF13881.6 EIM87678.1 - 8.2e-14 51.7 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EIM87678.1 - 0.07 12.9 0.1 0.48 10.2 0.1 2.2 1 1 0 1 1 1 0 Ubiquitin family COesterase PF00135.28 EIM87679.1 - 3e-90 303.5 0.0 3.4e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM87679.1 - 4.3e-08 33.3 0.3 2.5e-07 30.8 0.5 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold FHA PF00498.26 EIM87680.1 - 3.1e-10 40.3 0.0 4.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EIM87680.1 - 1.4e-05 25.3 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Glyco_hydro_20 PF00728.22 EIM87681.1 - 1.6e-26 93.6 0.1 1.6e-24 87.0 0.1 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EIM87681.1 - 0.00063 20.5 0.0 0.0016 19.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DEP PF00610.21 EIM87682.1 - 0.082 13.0 0.1 4.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) R3H PF01424.22 EIM87683.1 - 1.4e-12 47.4 0.1 2.3e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EIM87683.1 - 3.5e-06 26.9 28.5 2.7e-05 24.1 11.4 14.0 15 0 0 15 15 15 7 NF-X1 type zinc finger Transp_cyt_pur PF02133.15 EIM87684.1 - 2.3e-35 122.2 35.2 8.4e-35 120.4 35.2 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TBCA PF02970.16 EIM87685.1 - 0.065 13.6 0.4 0.11 12.8 0.4 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A YscO PF07321.12 EIM87685.1 - 0.15 12.0 3.1 0.25 11.3 3.1 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Cluap1 PF10234.9 EIM87685.1 - 0.26 10.7 1.7 0.38 10.1 1.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 TFIIA_gamma_N PF02268.16 EIM87686.1 - 3.1e-25 87.9 0.2 5.3e-25 87.2 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EIM87686.1 - 8.9e-23 80.2 0.2 1.4e-22 79.5 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit APH PF01636.23 EIM87687.1 - 7.5e-12 45.7 0.4 8.9e-10 38.9 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family F-box PF00646.33 EIM87688.1 - 2.3e-07 30.5 0.1 9.7e-07 28.5 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM87688.1 - 2.8e-07 30.3 0.0 7.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM87688.1 - 0.011 16.1 1.5 29 5.2 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) SPATIAL PF15256.6 EIM87690.1 - 0.47 10.8 4.7 0.33 11.2 2.9 1.4 1 1 0 1 1 1 0 SPATIAL SET PF00856.28 EIM87691.1 - 1.7e-12 48.1 0.0 3.7e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EIM87691.1 - 1e-10 41.5 9.9 1e-10 41.5 9.9 3.0 2 1 0 2 2 2 1 MYND finger CH PF00307.31 EIM87692.1 - 5.7e-77 254.9 0.0 4e-19 68.8 0.0 4.6 4 1 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EIM87692.1 - 3.5e-05 24.2 0.4 0.00032 21.1 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 EIM87692.1 - 4.8e-05 23.1 0.0 2.6 8.0 0.0 4.2 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.32 EIM87692.1 - 0.0026 17.2 0.0 0.93 9.2 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EIM87692.1 - 0.0028 17.5 0.0 0.069 13.1 0.0 3.1 4 0 0 4 4 4 1 EF-hand domain HAUS6_N PF14661.6 EIM87693.1 - 0.025 14.2 0.2 0.034 13.7 0.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2263 PF10021.9 EIM87693.1 - 0.048 14.0 0.7 0.58 10.5 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) PEARLI-4 PF05278.12 EIM87693.1 - 0.25 10.9 7.1 0.37 10.3 7.1 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) HMMR_N PF15905.5 EIM87693.1 - 0.34 10.4 10.0 0.48 9.8 10.0 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DAO PF01266.24 EIM87695.1 - 6.1e-44 151.0 0.3 7.2e-44 150.8 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM87695.1 - 2.2e-05 23.9 0.0 0.00018 20.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM87695.1 - 0.0004 20.4 0.1 0.037 14.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EIM87695.1 - 0.0007 19.8 0.1 0.0016 18.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIM87695.1 - 0.002 16.9 0.1 0.1 11.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM87695.1 - 0.064 12.5 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM87695.1 - 0.13 11.4 0.1 2.8 7.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mob1_phocein PF03637.17 EIM87696.1 - 7.2e-25 88.0 0.0 1.2e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Amidase PF01425.21 EIM87697.1 - 5.1e-84 282.8 0.0 7.2e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 Amidase Kinetochor_Ybp2 PF08568.10 EIM87698.1 - 9.2e-17 60.8 0.0 2.8e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Utp12 PF04003.12 EIM87698.1 - 0.084 13.2 0.2 0.3 11.4 0.2 2.0 1 0 0 1 1 1 0 Dip2/Utp12 Family Pkinase PF00069.25 EIM87700.1 - 1.3e-39 136.2 0.0 2.1e-26 92.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87700.1 - 2.6e-22 79.3 0.0 3.6e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM87700.1 - 9.9e-05 21.3 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM87700.1 - 0.037 14.0 0.0 0.091 12.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 EIM87701.1 - 2.6e-24 85.8 37.7 4.4e-24 85.1 37.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 EIM87702.1 - 2.4e-38 132.3 0.5 3e-38 132.0 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM87702.1 - 2.1e-14 53.9 0.6 3.7e-07 30.0 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family Ephrin_lbd PF01404.19 EIM87703.1 - 0.027 14.5 0.6 0.054 13.5 0.4 1.6 1 1 0 1 1 1 0 Ephrin receptor ligand binding domain COesterase PF00135.28 EIM87704.1 - 7e-75 252.8 0.0 9.6e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM87704.1 - 4e-06 26.9 0.3 1.1e-05 25.4 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold GST_N_3 PF13417.6 EIM87705.1 - 5e-16 58.9 0.0 8.7e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM87705.1 - 3.5e-13 49.7 0.0 6.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM87705.1 - 8e-07 29.3 0.1 1.5e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM87705.1 - 0.00012 22.1 0.8 0.0013 18.8 0.0 2.5 2 2 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EIM87705.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Peroxin-13_N PF04088.13 EIM87706.1 - 2.9e-41 141.1 0.2 5.3e-41 140.3 0.0 1.5 2 0 0 2 2 2 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 EIM87706.1 - 3.8e-10 39.2 2.8 0.00021 20.8 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EIM87706.1 - 6.7e-09 35.3 0.3 1.5e-08 34.2 0.3 1.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EIM87706.1 - 9.3e-09 35.0 1.8 3.9e-08 33.0 1.8 2.0 1 1 0 1 1 1 1 Variant SH3 domain Keratin_2_head PF16208.5 EIM87706.1 - 0.0016 18.6 28.0 0.0038 17.4 28.0 1.6 1 0 0 1 1 1 1 Keratin type II head Gti1_Pac2 PF09729.9 EIM87709.1 - 6.1e-09 36.2 0.6 6.1e-09 36.2 0.6 2.7 2 2 1 3 3 3 2 Gti1/Pac2 family DUF3395 PF11875.8 EIM87710.1 - 5.6e-34 117.3 0.0 1.1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EIM87710.1 - 5.1e-18 65.0 0.7 8.7e-18 64.2 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain DUF4381 PF14316.6 EIM87710.1 - 0.035 14.3 0.1 0.066 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DCP1 PF06058.13 EIM87711.1 - 8e-24 83.8 0.0 4.6e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Dcp1-like decapping family Glyco_transf_28 PF03033.20 EIM87712.1 - 9.3e-22 77.6 0.2 4.2e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EIM87712.1 - 0.0001 21.3 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EIM87712.1 - 0.00014 22.1 0.1 0.0011 19.2 0.0 2.5 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain DUF1840 PF08895.11 EIM87712.1 - 1.1 9.6 6.3 7.7 6.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) RNase_H PF00075.24 EIM87713.1 - 0.00016 21.8 0.8 0.0004 20.6 0.8 1.7 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 EIM87713.1 - 0.037 14.7 0.2 0.12 13.1 0.0 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Sec5 PF15469.6 EIM87714.1 - 1.9e-56 190.9 0.6 7e-56 189.0 0.0 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 EIM87714.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 zf-HC5HC2H PF13771.6 EIM87715.1 - 0.0054 17.0 2.9 0.028 14.7 0.1 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.29 EIM87715.1 - 0.0056 16.5 2.3 0.0056 16.5 2.3 2.9 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EIM87715.1 - 0.03 14.5 2.2 0.13 12.5 0.1 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain MULE PF10551.9 EIM87717.1 - 2e-05 24.9 0.0 4.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EIM87717.1 - 0.00089 18.9 1.4 0.0022 17.6 1.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger Motilin_ghrelin PF04644.12 EIM87718.1 - 0.03 14.1 2.3 0.068 13.0 2.3 1.6 1 0 0 1 1 1 0 Motilin/ghrelin Syntaxin-18_N PF10496.9 EIM87718.1 - 0.042 14.1 0.1 0.065 13.5 0.1 1.3 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus SAP130_C PF16014.5 EIM87720.1 - 8.7 5.3 9.1 11 5.0 9.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Retrotrans_gag PF03732.17 EIM87721.1 - 2.2e-12 47.1 0.0 5.4e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 EIM87721.1 - 3.9e-06 26.7 0.0 8.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Polbeta PF18765.1 EIM87723.1 - 3.3e-06 27.1 0.0 8.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 EIM87723.1 - 3.2e-05 24.1 0.1 6.3e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain Dynactin_p22 PF07426.11 EIM87723.1 - 0.23 11.3 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 SH3_9 PF14604.6 EIM87724.1 - 7.2e-14 51.4 0.2 1.6e-13 50.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 EIM87724.1 - 2.7e-12 46.6 0.0 5.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 EIM87724.1 - 2.8e-12 46.1 0.2 5.8e-12 45.0 0.2 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 EIM87724.1 - 6.9e-12 45.8 0.3 1.8e-11 44.5 0.3 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 EIM87724.1 - 1.2e-09 38.5 0.5 2.3e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EIM87724.1 - 6.5e-08 32.1 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_3 PF18016.1 EIM87724.1 - 0.00096 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EIM87724.1 - 0.014 15.7 0.2 0.027 14.7 0.2 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Mito_carr PF00153.27 EIM87725.1 - 5.9e-49 164.0 3.5 5e-16 58.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 EIM87725.1 - 0.013 15.6 0.1 3.8 7.7 0.1 2.5 2 0 0 2 2 2 0 PrcB C-terminal Sun2_CC2 PF18580.1 EIM87725.1 - 0.18 12.1 0.2 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Phosducin PF02114.16 EIM87726.1 - 3.6e-18 65.5 0.0 2.5e-08 33.2 0.0 3.1 3 0 0 3 3 3 3 Phosducin Pyridoxal_deC PF00282.19 EIM87728.1 - 2.2e-15 56.3 0.0 9.1e-08 31.2 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain DUF5566 PF17721.1 EIM87728.1 - 0.41 10.9 7.8 0.34 11.1 3.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5566) Herpes_gE PF02480.16 EIM87729.1 - 0.0016 17.3 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MGC-24 PF05283.11 EIM87729.1 - 0.013 15.9 5.2 0.013 15.9 5.2 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amnionless PF14828.6 EIM87729.1 - 0.026 13.4 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless Podoplanin PF05808.11 EIM87729.1 - 0.028 14.5 1.7 0.059 13.5 1.7 1.4 1 0 0 1 1 1 0 Podoplanin Mid2 PF04478.12 EIM87729.1 - 0.042 13.7 2.0 0.067 13.0 2.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Alpha_GJ PF03229.13 EIM87729.1 - 0.066 13.8 9.7 0.065 13.8 8.6 1.5 1 1 0 1 1 1 0 Alphavirus glycoprotein J Syndecan PF01034.20 EIM87729.1 - 0.34 10.8 0.6 0.59 10.1 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 EIM87729.1 - 0.52 10.2 6.7 1.4 8.8 6.7 1.6 1 1 0 1 1 1 0 TMEM154 protein family MFS_1 PF07690.16 EIM87730.1 - 1.7e-29 102.9 18.8 1.7e-29 102.9 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM87730.1 - 3.1e-06 26.3 7.9 0.0033 16.3 1.7 3.0 2 2 1 3 3 3 2 Sugar (and other) transporter Cys_Met_Meta_PP PF01053.20 EIM87732.1 - 2.6e-16 59.1 0.0 6.2e-14 51.3 0.0 2.5 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EIM87732.1 - 1.7e-08 34.0 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIM87733.1 - 0.00076 18.1 0.0 0.0022 16.6 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Trp_halogenase PF04820.14 EIM87734.1 - 1.3e-26 93.5 0.6 1.3e-16 60.5 0.1 3.5 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EIM87734.1 - 9.9e-08 31.6 0.7 3e-05 23.5 0.7 3.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM87734.1 - 0.0064 16.7 0.1 0.025 14.8 0.1 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM87734.1 - 0.031 13.9 0.2 2.2 7.8 0.1 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM87734.1 - 0.13 11.4 0.1 1.4 8.1 0.1 2.3 1 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EIM87736.1 - 2.7e-17 62.7 29.1 2.7e-17 62.7 29.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM87736.1 - 1.6e-09 37.2 0.9 3.9e-09 35.9 0.9 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EIM87736.1 - 0.00085 17.9 0.1 0.0016 17.0 0.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4713 PF15831.5 EIM87736.1 - 0.27 11.7 1.7 0.68 10.4 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) DUF5546 PF17700.1 EIM87737.1 - 0.055 13.8 0.2 0.87 10.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5546) Plavaka PF18759.1 EIM87738.1 - 1.7e-31 109.7 0.0 3.1e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase HMG_box PF00505.19 EIM87740.1 - 1.9e-11 44.2 0.7 1e-05 25.8 0.1 2.4 1 1 1 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM87740.1 - 3.1e-10 40.5 0.7 0.00024 21.6 0.1 2.3 1 1 1 2 2 2 2 HMG-box domain DUF1289 PF06945.13 EIM87740.1 - 0.16 11.8 1.0 15 5.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF3106 PF11304.8 EIM87740.1 - 0.45 11.0 7.3 4.3 7.9 4.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) HMG_box PF00505.19 EIM87742.1 - 1.1e-05 25.7 0.3 2.3e-05 24.7 0.3 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM87742.1 - 4.1e-05 24.1 0.5 4.9e-05 23.8 0.5 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EIM87743.1 - 0.0057 17.1 0.3 2.6 8.5 0.0 3.2 3 0 0 3 3 3 1 HMG (high mobility group) box DUF3106 PF11304.8 EIM87743.1 - 2.3 8.7 6.1 1.2 9.7 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF3328 PF11807.8 EIM87744.1 - 1.2e-11 44.8 3.2 7.1e-10 39.0 0.2 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF3328) DUF3984 PF13136.6 EIM87744.1 - 0.21 10.9 4.5 0.28 10.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF3328 PF11807.8 EIM87745.1 - 1.5e-14 54.3 2.2 8.4e-14 51.9 2.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SesA PF17107.5 EIM87748.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Dickkopf_N PF04706.12 EIM87749.1 - 0.0012 19.3 4.0 0.0013 19.2 4.0 1.1 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Toxin_12 PF07740.12 EIM87749.1 - 0.0087 16.7 6.1 0.014 16.1 6.1 1.3 1 0 0 1 1 1 1 Ion channel inhibitory toxin Conotoxin_I2 PF17557.2 EIM87749.1 - 0.022 14.9 7.2 0.027 14.6 7.2 1.2 1 0 0 1 1 1 0 I2-superfamily conotoxins Conotoxin PF02950.17 EIM87749.1 - 0.022 15.7 6.2 0.022 15.7 6.2 1.6 1 1 1 2 2 2 0 Conotoxin LEAP-2 PF07359.11 EIM87749.1 - 0.026 14.4 0.7 0.026 14.3 0.7 1.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Toxin_19 PF08088.12 EIM87749.1 - 0.041 14.0 5.2 0.051 13.7 5.2 1.2 1 0 0 1 1 1 0 Conotoxin I-superfamily Rab5ip PF07019.12 EIM87750.1 - 1.1e-20 73.9 4.1 1.4e-20 73.7 4.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) VIT_2 PF13757.6 EIM87751.1 - 0.15 12.0 0.1 0.46 10.4 0.1 1.7 1 1 1 2 2 2 0 Vault protein inter-alpha-trypsin domain Toxin_27 PF08099.11 EIM87751.1 - 0.4 10.8 5.5 0.73 10.0 5.5 1.4 1 0 0 1 1 1 0 Scorpion calcine family Toxin_12 PF07740.12 EIM87751.1 - 1.5 9.6 9.1 0.45 11.3 5.8 1.9 2 0 0 2 2 2 0 Ion channel inhibitory toxin TPR_2 PF07719.17 EIM87754.1 - 1.6e-15 55.9 1.3 0.00095 19.1 0.7 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIM87754.1 - 3.4e-10 39.3 2.8 0.00028 20.6 0.5 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIM87754.1 - 1.7e-09 37.2 0.9 0.00037 20.1 0.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 EIM87754.1 - 2.1e-05 24.7 2.7 1.2 9.5 0.0 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIM87754.1 - 0.0011 18.8 0.2 4.3 7.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIM87754.1 - 0.0092 16.3 0.1 0.25 11.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM87754.1 - 0.033 14.7 0.3 15 6.2 0.3 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EIM87754.1 - 0.05 13.7 1.2 3 8.0 0.3 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF4033 PF13225.6 EIM87754.1 - 0.07 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) DDE_Tnp_1_2 PF13586.6 EIM87754.1 - 0.15 12.4 0.7 5.4 7.5 0.1 2.8 2 0 0 2 2 2 0 Transposase DDE domain TPR_8 PF13181.6 EIM87754.1 - 0.25 11.6 2.8 6.2 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIM87754.1 - 1.3 9.7 7.9 1.2 9.8 2.8 3.3 2 2 0 2 2 2 0 Tetratricopeptide repeat Semialdhyde_dhC PF02774.18 EIM87755.1 - 9.5e-37 126.8 0.0 1.3e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EIM87755.1 - 4e-29 101.5 0.0 6.5e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EIM87755.1 - 0.061 14.0 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MFS_1 PF07690.16 EIM87761.1 - 5.2e-38 130.9 32.8 5.2e-38 130.9 32.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM87761.1 - 0.023 13.6 34.9 0.33 9.8 34.9 2.7 1 1 0 1 1 1 0 Sugar (and other) transporter DAO PF01266.24 EIM87762.1 - 1.4e-28 100.5 0.0 1.9e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM87762.1 - 8.3e-11 41.7 0.1 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM87762.1 - 2.1e-06 27.8 0.1 5.9e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIM87762.1 - 2.4e-05 23.8 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EIM87762.1 - 3.6e-05 23.0 0.1 0.0032 16.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EIM87762.1 - 3.8e-05 23.0 0.1 0.00016 20.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EIM87762.1 - 7e-05 22.2 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EIM87762.1 - 0.00052 18.8 0.0 0.037 12.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EIM87762.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GMC_oxred_N PF00732.19 EIM87762.1 - 0.0013 18.2 0.0 0.0065 15.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_7 PF13241.6 EIM87762.1 - 0.0014 19.0 0.0 0.0055 17.1 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 EIM87762.1 - 0.0014 18.0 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EIM87762.1 - 0.0052 16.1 0.0 0.087 12.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM87762.1 - 0.0055 17.2 0.1 0.042 14.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EIM87762.1 - 0.0079 15.6 0.0 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 ThiF family Trp_halogenase PF04820.14 EIM87762.1 - 0.018 13.9 0.5 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 EIM87762.1 - 0.019 15.0 0.0 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EIM87762.1 - 0.034 14.1 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 EIM87762.1 - 0.041 13.5 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EIM87762.1 - 0.048 13.0 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EIM87762.1 - 0.052 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.11 EIM87762.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) UDPG_MGDP_dh_N PF03721.14 EIM87762.1 - 0.082 12.5 0.2 0.39 10.3 0.1 2.1 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 EIM87762.1 - 0.15 11.4 0.1 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Retrotran_gag_2 PF14223.6 EIM87763.1 - 2.6e-06 27.2 0.0 4.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EIM87763.1 - 0.00077 19.4 1.7 0.0012 18.8 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C4H2 PF10146.9 EIM87763.1 - 0.02 15.2 0.2 0.02 15.2 0.2 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein zf-CCHC_4 PF14392.6 EIM87763.1 - 0.033 13.9 0.3 0.062 13.0 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EIM87763.1 - 0.087 12.7 0.5 0.25 11.2 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle 2-Hacid_dh_C PF02826.19 EIM87767.1 - 6.6e-54 182.0 0.0 8.8e-54 181.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM87767.1 - 6.9e-13 48.4 0.0 8.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIM87767.1 - 0.00013 22.2 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 EIM87767.1 - 0.025 15.1 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 EIM87767.1 - 0.17 12.5 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TPR_2 PF07719.17 EIM87768.1 - 6.7e-12 44.6 13.1 0.0043 17.1 0.0 7.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EIM87768.1 - 1.3e-11 43.8 0.3 1.4 8.9 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EIM87768.1 - 9.4e-07 29.0 7.6 0.13 12.6 0.0 6.2 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EIM87768.1 - 1.4e-06 27.8 0.0 0.4 10.4 0.0 4.4 4 0 0 4 4 4 2 TPR repeat TPR_9 PF13371.6 EIM87768.1 - 7.9e-05 22.7 6.9 0.0032 17.6 0.1 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIM87768.1 - 0.00012 22.2 0.1 0.011 16.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM87768.1 - 0.00022 21.8 17.4 2.1 9.4 0.0 7.6 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM87768.1 - 0.00036 21.1 9.3 0.0081 16.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM87768.1 - 0.0033 17.3 7.9 3.5 7.9 0.0 6.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM87768.1 - 0.031 14.8 0.9 31 5.2 0.0 4.4 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM87768.1 - 0.13 12.1 14.3 0.39 10.6 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat dsrm PF00035.26 EIM87771.1 - 1.2e-11 45.2 0.1 4.6e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Double-stranded RNA binding motif GPI-anchored PF10342.9 EIM87771.1 - 0.18 12.6 1.0 0.9 10.3 0.1 2.2 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family dsrm PF00035.26 EIM87772.1 - 2.9e-16 59.9 0.0 5.4e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Double-stranded RNA binding motif APT PF03440.14 EIM87772.1 - 0.002 18.1 0.0 0.88 9.6 0.0 2.2 2 0 0 2 2 2 2 Aerolysin/Pertussis toxin (APT) domain dsrm PF00035.26 EIM87773.1 - 2.5e-11 44.1 0.0 3.7e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif NOA36 PF06524.12 EIM87774.1 - 0.47 9.7 9.9 1.1 8.6 9.9 1.5 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 EIM87774.1 - 2.3 7.9 12.2 0.065 12.9 3.6 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) H2TH PF06831.14 EIM87776.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain WD40 PF00400.32 EIM87778.1 - 9.3e-53 175.0 9.3 7.7e-11 42.4 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM87778.1 - 2.1e-20 72.8 0.5 0.0041 17.4 0.0 5.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM87778.1 - 4.3e-10 39.1 3.5 0.17 10.8 0.0 5.2 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 EIM87778.1 - 5.4e-07 29.7 0.1 2.2e-06 27.7 0.0 2.1 2 1 0 2 2 1 1 NACHT domain Cytochrom_D1 PF02239.16 EIM87778.1 - 2.2e-06 26.5 2.4 0.0048 15.5 0.4 2.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain Frtz PF11768.8 EIM87778.1 - 3.7e-06 25.5 0.0 0.14 10.4 0.0 3.6 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EIM87778.1 - 3.8e-06 26.4 0.0 0.23 10.7 0.0 4.0 1 1 2 3 3 3 2 WD40-like domain Me-amine-dh_H PF06433.11 EIM87778.1 - 8.2e-06 24.9 0.0 0.18 10.6 0.0 3.4 2 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) AAA_16 PF13191.6 EIM87778.1 - 4.1e-05 24.0 0.0 0.00023 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 EIM87778.1 - 0.00051 19.9 1.8 52 3.9 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 EIM87778.1 - 0.0011 18.6 11.0 0.0025 17.4 9.7 2.2 2 1 0 2 2 2 1 PQQ-like domain NB-ARC PF00931.22 EIM87778.1 - 0.0025 17.1 0.0 0.0081 15.4 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 EIM87778.1 - 0.015 15.7 0.0 0.074 13.4 0.0 2.3 2 0 0 2 2 1 0 RNA helicase Roc PF08477.13 EIM87778.1 - 0.021 15.0 0.5 16 5.7 0.0 4.6 2 1 2 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EIM87778.1 - 0.035 14.5 0.0 0.35 11.3 0.0 2.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Peptidase_S9_N PF02897.15 EIM87778.1 - 0.042 12.6 2.7 8 5.1 0.1 3.5 1 1 3 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_22 PF13401.6 EIM87778.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PQQ PF01011.21 EIM87778.1 - 0.064 13.2 0.0 50 4.1 0.0 4.3 4 0 0 4 4 4 0 PQQ enzyme repeat APS_kinase PF01583.20 EIM87778.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF5570 PF17731.1 EIM87778.1 - 0.18 11.9 13.7 3.7 7.6 1.2 4.6 1 1 3 4 4 4 0 Family of unknown function (DUF5570) Med21 PF11221.8 EIM87778.1 - 0.25 11.6 1.3 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Rab5ip PF07019.12 EIM87779.1 - 1.8e-20 73.3 4.7 2.2e-20 73.0 4.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) F-box-like PF12937.7 EIM87781.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like PLU-1 PF08429.11 EIM87783.1 - 5e-45 154.1 0.1 3.6e-43 148.1 0.0 2.8 2 1 1 3 3 3 2 PLU-1-like protein JmjC PF02373.22 EIM87783.1 - 3e-41 140.4 0.2 8.7e-41 138.9 0.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EIM87783.1 - 1.9e-19 70.1 0.1 6.3e-19 68.4 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EIM87783.1 - 1.3e-16 60.2 1.6 2.9e-16 59.1 1.6 1.6 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EIM87783.1 - 1.5e-16 60.0 41.6 1.5e-11 43.9 7.2 4.5 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.16 EIM87783.1 - 2.4e-14 53.5 11.8 2.4e-14 53.5 11.8 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger 14-3-3 PF00244.20 EIM87784.1 - 1.6e-107 358.1 3.0 1.8e-107 357.9 3.0 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 EIM87784.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF TPR_19 PF14559.6 EIM87784.1 - 0.25 11.9 2.4 0.62 10.6 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 EIM87787.1 - 1.1e-08 34.9 0.4 3.4e-08 33.3 0.4 1.9 1 0 0 1 1 1 1 F-box-like Bac_rhamnosid6H PF17389.2 EIM87788.1 - 2.7e-16 59.8 0.1 4.8e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EIM87788.1 - 3.8e-14 52.2 1.9 4.2e-14 52.1 0.4 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_hydro_36 PF17167.4 EIM87788.1 - 9.5e-06 24.6 0.7 2.8e-05 23.0 0.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Trehalase PF01204.18 EIM87788.1 - 0.0037 16.2 0.1 0.0054 15.6 0.1 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.13 EIM87788.1 - 0.015 14.4 0.4 0.027 13.7 0.4 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region MscS_porin PF12795.7 EIM87789.1 - 0.073 12.6 2.1 0.12 11.9 2.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain F-box-like PF12937.7 EIM87789.1 - 0.097 12.6 0.0 1 9.3 0.0 2.6 2 1 0 2 2 2 0 F-box-like Sedlin_N PF04628.13 EIM87790.1 - 7.1e-17 61.8 0.0 9.5e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Phage_tail_X PF05489.12 EIM87790.1 - 0.041 13.5 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X F-box-like PF12937.7 EIM87791.1 - 9.7e-05 22.2 1.0 0.00038 20.3 1.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM87791.1 - 0.8 9.7 3.5 35 4.4 0.3 3.6 3 0 0 3 3 3 0 F-box domain RTP1_C1 PF10363.9 EIM87792.1 - 1.2e-33 115.6 1.9 3.5e-31 107.7 0.1 3.9 5 0 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EIM87792.1 - 0.00039 20.4 1.9 1.1 9.6 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat RTP1_C2 PF10304.9 EIM87792.1 - 0.057 13.1 3.7 0.11 12.2 0.1 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Sacchrp_dh_C PF16653.5 EIM87793.1 - 3.1e-80 270.1 0.0 4.6e-80 269.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EIM87793.1 - 1.5e-24 86.7 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EIM87793.1 - 3.8e-06 27.0 0.0 3e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EIM87793.1 - 0.0045 16.9 0.1 0.0072 16.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_C PF16653.5 EIM87794.1 - 1.6e-85 287.5 0.0 2.9e-85 286.6 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 EIM87794.1 - 1.7e-68 229.7 0.0 4.1e-68 228.5 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EIM87794.1 - 5.9e-25 86.9 1.6 2.3e-24 85.0 0.1 2.4 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 EIM87794.1 - 3.3e-23 82.4 1.1 1.4e-22 80.3 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 EIM87794.1 - 2.2e-06 28.3 0.0 0.00015 22.4 0.0 3.2 3 1 1 4 4 4 1 Methyltransferase domain Shikimate_DH PF01488.20 EIM87794.1 - 1.1e-05 25.5 0.1 8.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_12 PF08242.12 EIM87794.1 - 0.0009 20.0 0.0 0.0044 17.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 EIM87794.1 - 0.016 15.1 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DREV PF05219.12 EIM87794.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase DUF43 PF01861.16 EIM87794.1 - 0.089 12.0 0.1 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 EIM87794.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CtaG_Cox11 PF04442.14 EIM87795.1 - 0.037 14.1 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 TENA_THI-4 PF03070.16 EIM87796.1 - 1.2e-09 38.3 0.2 2.4e-09 37.3 0.2 1.4 1 1 0 1 1 1 1 TENA/THI-4/PQQC family DUF5596 PF18082.1 EIM87796.1 - 0.018 14.9 0.0 0.067 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) Cu-oxidase PF00394.22 EIM87797.1 - 8.8e-50 168.9 0.1 8.7e-46 155.9 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM87797.1 - 9.6e-40 135.5 1.5 2.6e-35 121.1 0.1 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM87797.1 - 6.5e-36 123.0 1.1 1.1e-31 109.3 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase RTA1 PF04479.13 EIM87799.1 - 9.2e-58 195.3 4.7 1.3e-57 194.7 4.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4186 PF13811.6 EIM87800.1 - 0.0074 16.3 0.6 0.45 10.6 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4186) VWA_2 PF13519.6 EIM87801.1 - 2.4e-09 37.8 0.0 7.4e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 EIM87801.1 - 1.1e-07 30.5 0.2 1.8e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EIM87801.1 - 6.9e-05 22.2 0.1 0.00019 20.8 0.1 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain VWA PF00092.28 EIM87801.1 - 0.00011 22.5 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.21 EIM87802.1 - 6e-08 32.8 31.4 8.6e-08 32.3 6.2 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EIM87802.1 - 1.7e-07 31.5 8.6 1.7e-07 31.5 8.6 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM87802.1 - 3.1e-05 23.9 1.5 3.1e-05 23.9 1.5 4.2 3 2 1 4 4 4 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EIM87802.1 - 0.00014 21.6 7.9 0.00014 21.6 7.9 4.9 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM87802.1 - 0.00015 21.6 6.4 0.00015 21.6 6.4 5.1 3 2 2 5 5 5 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EIM87802.1 - 0.00059 19.7 7.5 0.00059 19.7 7.5 3.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM87802.1 - 0.0019 18.0 9.0 0.0019 18.0 9.0 5.3 4 2 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EIM87802.1 - 0.0029 17.7 5.9 0.0029 17.7 5.9 4.8 3 2 2 5 5 5 1 zinc RING finger of MSL2 MOSC_N PF03476.16 EIM87803.1 - 2.4e-19 69.4 0.0 4.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EIM87803.1 - 4.6e-18 65.5 0.0 1e-17 64.4 0.0 1.6 1 1 1 2 2 2 1 MOSC domain 14-3-3 PF00244.20 EIM87805.1 - 9.9e-59 198.5 1.3 1.4e-55 188.2 1.2 2.0 2 0 0 2 2 2 2 14-3-3 protein DUF668 PF05003.12 EIM87805.1 - 0.028 14.9 0.7 0.13 12.7 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF668) Aminotran_1_2 PF00155.21 EIM87806.1 - 1.8e-11 43.9 0.0 1.4e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Dioxygenase_C PF00775.21 EIM87807.1 - 7.5e-41 139.5 0.0 1e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EIM87807.1 - 1.3e-25 89.1 0.0 2e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus zf-CCHC PF00098.23 EIM87809.1 - 1.6e-32 110.1 52.5 2.3e-06 27.4 3.1 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 EIM87809.1 - 2.2e-10 40.1 32.5 0.007 16.1 1.2 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 EIM87809.1 - 0.00048 19.8 0.5 0.00048 19.8 0.5 5.9 4 2 2 6 6 6 3 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EIM87809.1 - 0.015 15.1 3.0 0.015 15.1 3.0 6.1 5 1 1 6 6 6 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIM87809.1 - 0.11 12.4 37.5 4.4 7.3 0.0 6.1 3 1 3 6 6 6 0 Zinc knuckle Mu-like_Com PF10122.9 EIM87809.1 - 0.17 11.4 16.9 0.18 11.3 0.3 4.2 3 1 1 4 4 4 0 Mu-like prophage protein Com CorA PF01544.18 EIM87810.1 - 5.5e-47 160.5 0.4 7e-47 160.1 0.4 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EIM87810.1 - 0.032 14.3 0.6 0.068 13.2 0.4 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cyt_bd_oxida_II PF02322.15 EIM87812.1 - 0.14 11.5 6.5 0.17 11.2 6.5 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II E_Pc_C PF06752.12 EIM87812.1 - 0.18 11.9 1.4 0.26 11.4 1.4 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus AAA_12 PF13087.6 EIM87813.1 - 1.3e-31 109.8 0.1 3.2e-31 108.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM87813.1 - 3.8e-13 49.8 0.0 6.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM87813.1 - 1.5e-07 31.3 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM87813.1 - 4e-05 24.0 0.0 9.9e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Polyketide_cyc PF03364.20 EIM87814.1 - 1.8e-18 67.0 0.0 3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EspB PF05802.11 EIM87817.1 - 0.029 14.4 0.3 0.036 14.0 0.3 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein SPECT1 PF18680.1 EIM87817.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Plasmodium host cell traversal SPECT1 CHAT PF12770.7 EIM87818.1 - 9.9e-44 149.9 0.0 1.3e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Sec7 PF01369.20 EIM87821.1 - 3.3e-69 232.2 0.1 7.8e-69 231.0 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EIM87821.1 - 1.1e-40 139.1 3.7 1.1e-40 139.1 3.7 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EIM87821.1 - 1e-33 115.0 0.7 1e-33 115.0 0.7 5.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 EIM87821.1 - 8.4e-24 84.2 1.3 1.3e-20 73.8 0.1 3.2 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 EIM87821.1 - 0.48 10.5 2.0 5.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) DS PF01916.17 EIM87822.1 - 3.3e-136 453.2 0.0 3.8e-136 453.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DAO PF01266.24 EIM87823.1 - 2.7e-30 106.2 0.5 1.1e-24 87.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM87823.1 - 0.037 14.3 0.4 0.11 12.8 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM87823.1 - 0.2 11.6 0.4 0.84 9.6 0.1 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding BTB PF00651.31 EIM87824.1 - 0.0003 21.0 0.0 0.00072 19.8 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain DUF4180 PF13788.6 EIM87824.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) BTB PF00651.31 EIM87825.1 - 4.3e-05 23.7 0.0 8.4e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIM87826.1 - 0.00014 22.1 0.1 0.0068 16.6 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain SH3_9 PF14604.6 EIM87827.1 - 4.4e-37 125.7 9.6 1.4e-12 47.2 0.6 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 EIM87827.1 - 1.7e-36 123.6 10.2 4.2e-17 61.5 0.7 4.1 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 EIM87827.1 - 4.5e-27 93.5 0.0 3.1e-08 33.2 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 EIM87827.1 - 5.6e-27 93.4 0.0 1.1e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_10 PF17902.1 EIM87827.1 - 0.0018 18.3 0.1 0.27 11.3 0.0 2.8 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 EIM87827.1 - 0.0038 17.5 4.3 9.4 6.6 0.9 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 EIM87827.1 - 0.0081 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_TFIIH PF08567.11 EIM87827.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain hSH3 PF14603.6 EIM87827.1 - 0.093 13.2 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Helically-extended SH3 domain Asp-B-Hydro_N PF05279.11 EIM87827.1 - 0.52 10.3 27.1 1.3 9.1 27.1 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 EIM87827.1 - 1.3 7.1 13.6 2.2 6.3 13.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4778 PF16008.5 EIM87827.1 - 2.7 7.9 12.9 5 7.1 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) BTB PF00651.31 EIM87828.1 - 2.1e-05 24.7 0.0 0.00094 19.4 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 EIM87829.1 - 0.00034 20.8 0.0 0.00035 20.8 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain eIF3m_C_helix PF18005.1 EIM87830.1 - 3.2e-12 45.9 0.1 7.4e-12 44.7 0.1 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 EIM87830.1 - 6.4e-10 39.5 0.0 2.2e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain UBA2_C PF16195.5 EIM87831.1 - 2.2 9.0 6.8 1.1 10.1 0.6 2.4 2 1 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DUF948 PF06103.11 EIM87832.1 - 0.07 13.4 0.0 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_M24 PF00557.24 EIM87833.1 - 3.8e-50 170.5 0.0 4.7e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EIM87833.1 - 1.4e-15 57.3 11.8 2.5e-15 56.5 11.8 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding CEBP_ZZ PF16366.5 EIM87833.1 - 0.012 15.9 0.7 0.027 14.7 0.7 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-MYND PF01753.18 EIM87833.1 - 0.97 9.6 9.5 2.2 8.4 9.5 1.6 1 0 0 1 1 1 0 MYND finger CDC27 PF09507.10 EIM87834.1 - 0.52 9.6 6.2 0.73 9.2 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CHAT PF12770.7 EIM87835.1 - 1.2e-33 116.8 0.0 1.9e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 CHAT domain DUF5127 PF17168.4 EIM87836.1 - 2.7e-77 259.6 8.3 5e-77 258.7 8.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM87836.1 - 1.4e-72 243.0 0.2 5.6e-72 241.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM87836.1 - 1.3e-61 207.9 0.8 1.3e-61 207.9 0.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM87836.1 - 6.2e-09 35.3 0.1 2.3e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 EIM87836.1 - 0.00095 18.5 0.2 0.0022 17.3 0.2 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain BsuBI_PstI_RE_N PF17728.1 EIM87836.1 - 0.0018 18.2 0.1 0.0038 17.1 0.1 1.5 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease HTH domain zf-C2H2 PF00096.26 EIM87837.1 - 3.7e-25 86.9 60.8 0.0036 17.7 0.3 10.7 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM87837.1 - 4e-19 67.6 54.5 0.034 15.0 0.3 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM87837.1 - 1e-09 38.4 60.8 6.5e-06 26.3 1.8 10.8 13 0 0 13 13 13 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 EIM87837.1 - 6.3e-07 29.6 21.8 0.006 16.9 2.9 5.3 3 1 3 6 6 6 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EIM87837.1 - 9.5e-05 22.6 20.9 1 9.7 0.9 7.9 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EIM87837.1 - 0.21 11.6 0.2 0.21 11.6 0.2 8.1 9 0 0 9 9 9 0 C2H2-type zinc finger zf-met PF12874.7 EIM87837.1 - 0.86 10.1 24.0 1.4 9.5 2.6 6.6 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Transpos_assoc PF13963.6 EIM87837.1 - 2.2 8.7 10.2 5.9 7.3 0.6 3.7 3 1 0 3 3 3 0 Transposase-associated domain zf_ZIC PF18366.1 EIM87837.1 - 2.5 8.3 6.4 96 3.2 0.0 4.8 5 0 0 5 5 5 0 Zic proteins zinc finger domain HemY_N PF07219.13 EIM87838.1 - 0.11 12.7 0.5 4 7.7 0.1 2.2 2 0 0 2 2 2 0 HemY protein N-terminus ORMDL PF04061.14 EIM87839.1 - 5.2e-47 159.1 2.5 7.3e-47 158.6 2.5 1.2 1 0 0 1 1 1 1 ORMDL family VIR_N PF15912.5 EIM87840.1 - 9.3e-05 22.1 6.1 9.3e-05 22.1 6.1 2.4 2 1 0 2 2 2 1 Virilizer, N-terminal DUF2009 PF09418.10 EIM87844.1 - 8e-210 697.7 0.1 9.3e-210 697.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 EIM87844.1 - 5.6e-05 23.2 7.3 0.0001 22.4 7.3 1.4 1 0 0 1 1 1 1 B-box zinc finger 4HB_MCP_1 PF12729.7 EIM87844.1 - 0.017 14.7 0.3 0.03 13.9 0.3 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Fez1 PF06818.15 EIM87844.1 - 0.024 15.1 0.5 0.044 14.2 0.5 1.4 1 0 0 1 1 1 0 Fez1 CEBP_ZZ PF16366.5 EIM87844.1 - 0.052 13.8 7.6 0.11 12.7 7.6 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RasGAP_C PF03836.15 EIM87844.1 - 0.11 12.7 1.2 0.22 11.7 1.2 1.4 1 0 0 1 1 1 0 RasGAP C-terminus DUF5127 PF17168.4 EIM87845.1 - 2.6e-77 259.6 8.5 4.6e-77 258.8 8.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM87845.1 - 2.6e-74 248.6 0.2 1e-73 246.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM87845.1 - 5.9e-54 183.0 1.0 5.9e-54 183.0 1.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM87845.1 - 1.2e-08 34.4 0.1 4.4e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 EIM87845.1 - 0.00038 19.8 0.1 0.00091 18.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain BsuBI_PstI_RE_N PF17728.1 EIM87845.1 - 0.027 14.4 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain Atg31 PF09795.9 EIM87845.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 31 Clr2_transil PF16761.5 EIM87846.1 - 2.2e-15 57.2 1.5 5.2e-15 56.0 1.5 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 STIMATE PF12400.8 EIM87847.1 - 5.5e-38 130.3 6.1 9e-38 129.6 6.1 1.3 1 0 0 1 1 1 1 STIMATE family Clr2_transil PF16761.5 EIM87848.1 - 8.5e-19 68.2 1.2 1.5e-18 67.4 0.3 1.9 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 GTP_EFTU PF00009.27 EIM87849.1 - 2.1e-44 151.4 0.0 3.4e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIM87849.1 - 2.1e-36 124.6 0.5 1.4e-34 118.8 0.1 3.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EIM87849.1 - 1.5e-09 38.1 2.0 2.1e-09 37.6 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM87849.1 - 0.008 16.3 0.1 0.054 13.6 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIM87849.1 - 0.06 12.7 0.0 2 7.7 0.0 2.7 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Peptidase_S28 PF05577.12 EIM87851.1 - 1.7e-47 162.2 0.1 4.3e-47 160.9 0.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EIM87851.1 - 0.043 13.3 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family THF_DHG_CYH PF00763.23 EIM87852.1 - 1e-21 77.4 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EIM87852.1 - 1.4e-19 69.9 0.0 2e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EIM87852.1 - 0.014 15.4 0.1 0.08 13.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 EIM87852.1 - 0.015 15.7 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 EIM87852.1 - 0.034 13.1 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family RRS1 PF04939.12 EIM87853.1 - 5.3e-56 189.0 1.2 8.5e-56 188.3 1.2 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TFIIB PF00382.19 EIM87854.1 - 2.3e-32 110.8 0.0 4e-20 71.6 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EIM87854.1 - 8.1e-12 44.5 1.5 1.4e-11 43.7 1.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.15 EIM87854.1 - 0.0049 17.3 1.0 15 6.1 0.0 3.6 2 1 2 4 4 4 2 Guanylin precursor HTH_5 PF01022.20 EIM87854.1 - 0.04 13.8 0.1 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Cyclin_C PF02984.19 EIM87854.1 - 0.044 13.9 0.0 0.49 10.5 0.1 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_N PF00134.23 EIM87854.1 - 0.057 13.2 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain RB_B PF01857.20 EIM87854.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain TMIE PF16038.5 EIM87854.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.6 2 0 0 2 2 2 0 TMIE protein Uds1 PF15456.6 EIM87855.1 - 7.8e-33 113.4 12.7 7.8e-33 113.4 12.7 6.1 4 2 1 5 5 5 1 Up-regulated During Septation DUF4200 PF13863.6 EIM87855.1 - 0.018 15.4 7.4 0.018 15.4 7.4 7.1 4 2 1 6 6 6 0 Domain of unknown function (DUF4200) DUF2064 PF09837.9 EIM87855.1 - 0.33 10.8 3.7 0.39 10.6 0.4 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Clr2_transil PF16761.5 EIM87856.1 - 1.5e-13 51.4 0.0 3.8e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 DUF4054 PF13262.6 EIM87857.1 - 0.018 15.1 1.2 0.037 14.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) DUF16 PF01519.16 EIM87858.1 - 0.016 15.7 0.4 0.063 13.8 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF842 PF05811.13 EIM87858.1 - 0.02 14.6 0.2 0.03 14.0 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TMCO5 PF14992.6 EIM87858.1 - 0.033 13.8 0.3 0.039 13.5 0.3 1.1 1 0 0 1 1 1 0 TMCO5 family RecO_N PF11967.8 EIM87858.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Recombination protein O N terminal DGF-1_C PF11040.8 EIM87858.1 - 1 9.4 8.4 12 6.0 5.1 2.5 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF4178 PF13785.6 EIM87859.1 - 0.086 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) zf-RING_2 PF13639.6 EIM87862.1 - 5.4e-08 33.0 6.1 2.9e-07 30.7 3.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EIM87862.1 - 2.8e-07 30.7 2.0 2.8e-07 30.7 2.0 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EIM87862.1 - 7.9e-06 25.6 4.0 7.9e-06 25.6 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM87862.1 - 8.8e-05 22.2 1.8 0.0081 15.9 0.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EIM87862.1 - 0.00019 21.3 0.3 0.00037 20.4 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM87862.1 - 0.00054 19.8 2.0 0.00054 19.8 2.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM87862.1 - 0.00081 19.2 0.8 0.0016 18.2 0.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EIM87862.1 - 0.001 18.9 1.7 0.001 18.9 1.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM87862.1 - 0.0012 18.8 0.6 0.0028 17.7 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EIM87862.1 - 0.042 13.5 1.7 0.098 12.3 1.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EIM87862.1 - 0.045 13.8 2.6 0.13 12.4 2.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.14 EIM87862.1 - 0.26 11.0 3.6 0.58 9.9 3.6 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3H2C3 PF17122.5 EIM87862.1 - 0.3 11.2 2.6 0.63 10.1 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 EIM87862.1 - 0.32 10.8 1.9 0.68 9.8 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EIM87862.1 - 0.52 10.5 4.6 1.2 9.3 4.6 1.5 1 0 0 1 1 1 0 RING-variant domain DUF4692 PF15763.5 EIM87862.1 - 0.52 10.8 2.2 28 5.1 0.2 2.6 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Nnf1 PF03980.14 EIM87863.1 - 5.4e-11 42.8 0.1 1.2e-10 41.8 0.1 1.5 1 0 0 1 1 1 1 Nnf1 CENP-Q PF13094.6 EIM87863.1 - 0.034 14.3 2.5 0.077 13.2 2.5 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YvbH_ext PF11724.8 EIM87863.1 - 0.054 13.8 0.3 6.1 7.2 0.0 2.7 2 1 0 2 2 2 0 YvbH-like oligomerisation region DUF5532 PF17673.1 EIM87863.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5532) CK_II_beta PF01214.18 EIM87863.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Tachystatin_B PF11478.8 EIM87863.1 - 0.22 11.5 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B APG6_N PF17675.1 EIM87863.1 - 0.37 11.3 8.5 0.95 10.0 8.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Glyco_hydro_53 PF07745.13 EIM87864.1 - 1.2e-75 254.6 0.0 1.5e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 tRNA-synt_2e PF02091.15 EIM87864.1 - 0.032 13.5 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit GMC_oxred_N PF00732.19 EIM87865.1 - 8.8e-55 186.2 0.0 1.4e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87865.1 - 1.8e-25 90.1 0.0 3.6e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM87865.1 - 0.0022 17.1 0.4 0.0035 16.4 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM87865.1 - 0.0047 16.1 0.9 1.3 8.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EIM87865.1 - 0.082 12.1 1.2 0.19 11.0 0.6 1.8 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 EIM87865.1 - 0.18 10.7 0.1 0.26 10.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 EIM87865.1 - 0.19 11.3 2.3 1.9 7.9 0.4 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 EIM87866.1 - 4e-56 190.6 0.0 6.5e-56 189.9 0.0 1.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87866.1 - 8.2e-32 110.7 0.0 1.4e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM87866.1 - 0.0003 20.0 0.2 0.00045 19.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM87866.1 - 0.004 16.3 0.1 0.68 8.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM87866.1 - 0.029 14.6 0.1 0.068 13.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM87866.1 - 0.05 13.2 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EIM87866.1 - 0.12 11.6 0.1 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DUF4079 PF13301.6 EIM87867.1 - 0.39 10.9 3.5 0.89 9.7 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) IPP-2 PF04979.14 EIM87868.1 - 1.6e-18 67.8 7.1 2.1e-17 64.1 7.1 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3188 PF11384.8 EIM87869.1 - 0.069 12.9 0.5 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Pro-kuma_activ PF09286.11 EIM87870.1 - 1.4e-38 132.4 0.0 2.5e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM87870.1 - 0.00012 21.5 1.0 0.00012 21.5 1.0 1.6 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.11 EIM87871.1 - 2.6e-40 138.0 0.0 4.5e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain HicA_toxin PF07927.12 EIM87872.1 - 5.1e-05 23.2 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Pro-kuma_activ PF09286.11 EIM87873.1 - 3.4e-36 124.6 0.0 5.6e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM87873.1 - 8.9e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family RIO1 PF01163.22 EIM87875.1 - 2.3e-07 30.6 0.0 5.3e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 EIM87875.1 - 5.3e-07 29.3 0.0 7.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM87875.1 - 6.5e-05 23.0 0.3 0.00019 21.5 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EIM87875.1 - 0.003 16.9 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM87875.1 - 0.035 12.9 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EIM87875.1 - 0.041 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Polyketide_cyc PF03364.20 EIM87875.1 - 0.12 12.6 1.3 0.29 11.3 0.1 2.0 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport RIO1 PF01163.22 EIM87876.1 - 3.6e-06 26.7 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EIM87876.1 - 8.4e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM87876.1 - 8.3e-05 22.6 0.2 0.00025 21.0 0.2 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EIM87876.1 - 0.0095 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EIM87876.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Polyketide_cyc PF03364.20 EIM87876.1 - 0.13 12.4 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Pkinase_fungal PF17667.1 EIM87876.1 - 0.2 10.4 0.1 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase TIP41 PF04176.13 EIM87878.1 - 2.3e-57 193.2 0.0 2.9e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.11 EIM87879.1 - 1.3e-34 119.9 13.5 1.3e-25 90.2 0.0 5.4 4 2 1 5 5 5 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 EIM87879.1 - 0.0058 17.0 0.0 0.028 14.8 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 EIM87879.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIM87879.1 - 0.08 12.5 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Hep_59 PF07052.11 EIM87882.1 - 3.4e-30 104.9 3.9 3.4e-30 104.9 3.9 2.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF4748 PF15932.5 EIM87882.1 - 7.3 6.4 7.5 0.61 9.9 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4748) SurE PF01975.17 EIM87883.1 - 5.3e-40 137.3 0.0 7.4e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE p450 PF00067.22 EIM87884.1 - 2.3e-74 250.8 0.0 2.7e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_Tnp_Tn3 PF01526.17 EIM87884.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain GMC_oxred_N PF00732.19 EIM87885.1 - 1e-57 195.8 0.0 1.3e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87885.1 - 5.5e-32 111.3 0.1 8.8e-32 110.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM87885.1 - 3.9e-05 22.9 0.9 5.5e-05 22.4 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EIM87885.1 - 0.00013 21.3 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EIM87885.1 - 0.00032 20.9 0.1 0.003 17.8 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIM87885.1 - 0.0021 16.8 0.5 0.029 13.1 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM87885.1 - 0.0025 17.2 0.3 0.39 9.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM87885.1 - 0.0032 16.6 0.2 0.012 14.8 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM87885.1 - 0.058 12.6 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM87885.1 - 0.089 12.4 1.7 0.13 11.8 0.4 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 EIM87886.1 - 2.5e-51 174.8 0.0 3.6e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM87886.1 - 1.2e-30 106.9 0.0 2e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM87886.1 - 4.6e-05 23.6 0.5 0.00013 22.1 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM87886.1 - 0.00024 20.3 0.4 0.0052 15.9 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EIM87886.1 - 0.0016 18.1 1.7 0.0036 17.0 1.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM87886.1 - 0.0019 17.3 0.2 0.0034 16.5 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIM87886.1 - 0.0065 15.7 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM87886.1 - 0.0094 14.7 0.1 0.016 13.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM87886.1 - 0.014 14.7 0.1 0.037 13.3 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM87886.1 - 0.061 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.25 EIM87887.1 - 4.2e-22 78.6 0.0 2e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87887.1 - 7.8e-16 58.3 0.0 1.6e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87887.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 KR domain T6_Ig_like PF18002.1 EIM87889.1 - 0.052 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 T6 antigen Ig like domain Plavaka PF18759.1 EIM87892.1 - 2.7e-117 391.6 0.0 3.7e-117 391.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF2303 PF10065.9 EIM87892.1 - 0.00086 18.5 0.0 0.004 16.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2303) DTHCT PF08070.11 EIM87893.1 - 0.021 15.5 9.2 0.021 15.5 9.2 7.0 6 1 2 8 8 8 0 DTHCT (NUC029) region Plavaka PF18759.1 EIM87895.1 - 1.4e-103 346.5 0.0 2.2e-103 345.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF4874 PF16173.5 EIM87899.1 - 0.046 13.4 0.0 0.079 12.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4874) Pkinase PF00069.25 EIM87900.1 - 1.3e-06 28.0 0.0 4.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87900.1 - 0.0018 17.6 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM87900.1 - 0.069 11.9 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HopA1 PF17914.1 EIM87900.1 - 0.089 12.5 0.0 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 HopA1 effector protein family MFS_1 PF07690.16 EIM87901.1 - 9.8e-18 64.2 54.8 2.3e-10 40.0 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Btz PF09405.10 EIM87902.1 - 1.1e-08 35.4 0.5 1.1e-08 35.4 0.5 2.5 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding DHQ_synthase PF01761.20 EIM87903.1 - 2.3e-53 181.0 0.0 2.8e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EIM87903.1 - 3.7e-12 46.5 0.0 5.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EIM87903.1 - 0.00016 20.6 0.0 0.00047 19.1 0.0 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase MFS_1 PF07690.16 EIM87904.1 - 6.8e-19 68.0 50.8 1.9e-10 40.2 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF751 PF05421.11 EIM87904.1 - 0.16 12.7 4.6 0.83 10.4 4.6 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF751) WD40 PF00400.32 EIM87905.1 - 2e-10 41.0 11.2 0.001 19.8 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM87905.1 - 5.3e-07 29.9 0.5 0.043 14.1 0.0 4.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM87905.1 - 0.00013 21.9 0.0 0.24 11.3 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EIM87905.1 - 0.0065 16.4 0.0 0.63 10.1 0.0 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat LNS2 PF08235.13 EIM87908.1 - 1.7e-98 328.6 0.0 2.3e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EIM87908.1 - 3.6e-28 97.5 0.0 1.1e-25 89.6 0.0 2.5 1 1 0 1 1 1 1 lipin, N-terminal conserved region Arginase PF00491.21 EIM87909.1 - 6.7e-81 271.9 0.2 8.4e-81 271.5 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EIM87909.1 - 0.056 13.7 0.1 0.079 13.2 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain Complex1_LYR PF05347.15 EIM87910.1 - 7.2e-08 32.4 1.0 2.3e-07 30.7 1.0 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EIM87910.1 - 0.17 12.7 0.3 0.25 12.1 0.3 1.5 1 1 0 1 1 1 0 Complex1_LYR-like JAB PF01398.21 EIM87911.1 - 3.7e-21 75.3 0.1 6.1e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EIM87911.1 - 7.9e-15 55.3 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 EIM87911.1 - 0.0079 16.3 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) A_amylase_inhib PF01356.19 EIM87911.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase inhibitor RLI PF04068.15 EIM87912.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI AFG1_ATPase PF03969.16 EIM87914.1 - 1.1e-94 317.3 0.0 2.7e-90 302.9 0.0 2.9 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EIM87914.1 - 1.5e-05 25.4 0.0 9.9e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EIM87914.1 - 0.00047 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM87914.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EIM87914.1 - 0.0098 15.3 0.0 0.032 13.7 0.0 1.8 1 1 0 1 1 1 1 Bacterial TniB protein ABC_tran PF00005.27 EIM87914.1 - 0.021 15.4 0.0 16 6.0 0.0 2.9 3 1 1 4 4 4 0 ABC transporter AAA_5 PF07728.14 EIM87914.1 - 0.029 14.4 0.0 0.075 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EIM87914.1 - 0.056 13.3 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EIM87914.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EIM87914.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ApoB100_C PF12491.8 EIM87914.1 - 0.099 12.6 0.2 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal Bac_DnaA PF00308.18 EIM87914.1 - 0.2 11.5 0.1 1.8 8.4 0.0 2.2 3 0 0 3 3 3 0 Bacterial dnaA protein ORC6 PF05460.13 EIM87914.1 - 0.83 8.9 3.3 0.56 9.4 1.1 1.8 2 1 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) UreF PF01730.16 EIM87916.1 - 1.5e-25 90.3 0.4 2.3e-25 89.7 0.4 1.3 1 0 0 1 1 1 1 UreF RRN3 PF05327.11 EIM87917.1 - 8.8e-187 622.0 0.0 2.1e-186 620.8 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_Rpc4 PF05132.14 EIM87918.1 - 0.024 15.0 0.1 0.038 14.4 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pkinase PF00069.25 EIM87919.1 - 4.1e-09 36.2 0.0 2.2e-07 30.5 0.0 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87919.1 - 0.0014 18.0 0.0 0.0087 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EIM87919.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EIM87919.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CNDH2_N PF06278.11 EIM87920.1 - 0.017 15.3 0.6 0.036 14.3 0.6 1.6 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Pkinase PF00069.25 EIM87921.1 - 8.3e-09 35.2 0.0 7.8e-07 28.7 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87921.1 - 0.0013 18.1 0.0 0.0031 16.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EIM87921.1 - 0.027 13.5 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UPF0449 PF15136.6 EIM87922.1 - 0.036 14.5 0.6 0.1 13.1 0.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 RFX5_N PF18326.1 EIM87922.1 - 0.083 12.7 0.3 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 RFX5 N-terminal domain DnaB PF00772.21 EIM87922.1 - 0.086 12.9 0.3 0.34 11.0 0.1 2.1 2 1 0 2 2 2 0 DnaB-like helicase N terminal domain DUF1451 PF07295.11 EIM87922.1 - 0.13 12.3 1.0 1.4 9.0 1.5 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain MVP_shoulder PF11978.8 EIM87923.1 - 0.14 12.2 0.1 0.63 10.1 0.1 2.1 1 1 0 1 1 1 0 Shoulder domain Pkinase PF00069.25 EIM87924.1 - 6.4e-06 25.7 0.0 0.0003 20.3 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87924.1 - 0.18 11.1 0.0 0.95 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Ubiquitin_3 PF14836.6 EIM87925.1 - 0.0048 16.8 0.9 0.65 10.0 0.2 2.8 2 1 0 2 2 2 2 Ubiquitin-like domain DUF2605 PF10792.9 EIM87925.1 - 0.11 12.4 1.4 13 5.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) DUF4407 PF14362.6 EIM87925.1 - 0.17 11.2 5.5 0.24 10.7 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med2 PF11214.8 EIM87925.1 - 0.24 11.6 3.2 1.5 9.0 1.6 2.5 2 1 0 2 2 2 0 Mediator complex subunit 2 DUF4658 PF15555.6 EIM87926.1 - 0.017 15.2 0.4 0.033 14.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Pkinase PF00069.25 EIM87927.1 - 3.3e-06 26.6 0.0 7e-05 22.3 0.0 2.3 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87927.1 - 0.0019 17.5 0.0 0.0061 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM87927.1 - 0.032 13.0 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haem_bd PF14376.6 EIM87929.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Haem-binding domain YscO PF07321.12 EIM87930.1 - 0.11 12.4 0.9 0.18 11.7 0.9 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO Raftlin PF15250.6 EIM87931.1 - 0.15 10.8 0.9 0.34 9.6 0.9 1.5 1 0 0 1 1 1 0 Raftlin Pkinase PF00069.25 EIM87932.1 - 1.8e-07 30.8 0.0 1.5e-06 27.8 0.0 2.1 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87932.1 - 0.00011 21.6 0.0 0.00051 19.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EIM87932.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIM87932.1 - 0.19 10.4 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EIM87934.1 - 1.5e-13 50.8 0.0 1.4e-06 27.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87934.1 - 4.6e-09 36.0 0.0 0.0012 18.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM87934.1 - 0.0012 17.7 0.0 0.29 9.9 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 EIM87934.1 - 0.003 16.9 0.3 0.2 11.0 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EIM87934.1 - 0.07 12.7 0.0 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EIM87934.1 - 0.15 11.1 0.1 5 6.1 0.1 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 FAD_binding_3 PF01494.19 EIM87935.1 - 6.6e-57 193.3 0.0 9.4e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM87935.1 - 1.4e-05 25.2 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Aldedh PF00171.22 EIM87936.1 - 3.6e-147 490.6 0.0 4.4e-147 490.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM87936.1 - 0.0026 16.9 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Bin3 PF06859.12 EIM87937.1 - 8.4e-31 106.8 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 EIM87937.1 - 5e-11 43.2 0.0 2.5e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EIM87937.1 - 5.6e-11 42.5 0.0 8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM87937.1 - 6.8e-11 42.2 0.0 3.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EIM87937.1 - 1.2e-08 35.5 0.0 0.0012 19.5 0.0 2.5 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EIM87937.1 - 1.4e-05 25.7 0.0 0.13 13.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.7 EIM87937.1 - 7.4e-05 22.7 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EIM87937.1 - 0.00042 19.8 0.0 0.00092 18.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EIM87937.1 - 0.0019 17.8 0.0 0.0054 16.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 EIM87937.1 - 0.0083 15.4 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EIM87937.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HAD_2 PF13419.6 EIM87938.1 - 7.2e-20 71.8 0.0 9.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM87938.1 - 3.2e-10 40.7 0.1 2.1e-08 34.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM87938.1 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EIM87938.1 - 0.0021 18.5 0.0 0.0031 17.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box PF00646.33 EIM87940.1 - 1.2e-06 28.2 1.5 1.8e-06 27.7 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM87940.1 - 3.9e-06 26.7 0.1 9.5e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like zf-HC5HC2H_2 PF13832.6 EIM87941.1 - 0.017 15.3 0.3 0.02 15.1 0.3 1.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain Plavaka PF18759.1 EIM87942.1 - 3.3e-16 59.4 0.1 1e-14 54.5 0.1 2.8 1 1 0 1 1 1 1 Plavaka transposase Y_phosphatase3 PF13350.6 EIM87943.1 - 1e-54 186.0 0.0 6.7e-54 183.3 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EIM87943.1 - 0.0094 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EIM87943.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EIM87943.1 - 0.18 11.4 0.0 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Glyco_hydro_32N PF00251.20 EIM87944.1 - 1.4e-80 271.2 3.1 1.6e-80 270.9 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EIM87944.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Epimerase PF01370.21 EIM87945.1 - 8.9e-19 67.9 0.1 3.3e-18 66.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM87945.1 - 5.1e-13 48.7 0.1 8.4e-13 48.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM87945.1 - 1.6e-10 41.1 0.5 2.6e-10 40.5 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIM87945.1 - 2.6e-08 33.4 0.0 0.0013 17.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 EIM87945.1 - 2.5e-06 27.2 1.6 3.9e-06 26.6 1.6 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM87945.1 - 4.8e-06 26.2 0.4 1.1e-05 25.0 0.4 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EIM87945.1 - 0.0018 17.7 1.6 0.023 14.2 0.5 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM87945.1 - 0.029 13.5 0.6 0.04 13.1 0.6 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Nup188_C PF18378.1 EIM87945.1 - 0.055 12.3 0.5 0.1 11.4 0.3 1.4 2 0 0 2 2 2 0 Nuclear pore protein NUP188 C-terminal domain Ribosomal_L1 PF00687.21 EIM87946.1 - 5.6e-46 156.9 1.6 6.6e-46 156.6 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Snf7 PF03357.21 EIM87947.1 - 2.1e-46 157.7 11.6 2.5e-46 157.4 11.6 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 EIM87947.1 - 0.00075 19.9 2.1 0.035 14.6 0.3 2.7 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EIM87947.1 - 0.0024 18.2 5.3 0.59 10.6 0.0 3.4 2 1 1 3 3 3 2 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 EIM87947.1 - 0.032 14.6 15.0 0.087 13.2 12.0 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TRPM_tetra PF16519.5 EIM87947.1 - 0.089 12.9 0.4 0.089 12.9 0.4 2.6 3 0 0 3 3 3 0 Tetramerisation domain of TRPM NuA4 PF09340.10 EIM87947.1 - 0.13 12.2 0.4 0.44 10.5 0.4 2.0 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 RBFA PF02033.18 EIM87947.1 - 0.14 12.7 0.9 0.28 11.6 0.7 1.8 1 1 0 1 1 1 0 Ribosome-binding factor A RPW8 PF05659.11 EIM87947.1 - 0.21 11.3 5.8 0.2 11.3 2.2 2.4 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5344 PF17279.2 EIM87947.1 - 0.27 11.9 8.8 1.1 9.9 5.1 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5344) FlxA PF14282.6 EIM87947.1 - 0.37 10.8 11.5 0.13 12.3 6.0 2.3 1 1 1 2 2 2 0 FlxA-like protein FapA PF03961.13 EIM87947.1 - 0.74 8.3 8.6 1.7 7.2 1.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A GPS2_interact PF15784.5 EIM87947.1 - 3.4 8.2 7.1 0.81 10.2 1.0 2.3 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Lin-8 PF03353.15 EIM87948.1 - 4.8 6.7 7.6 0.96 8.9 0.9 2.3 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist Syja_N PF02383.18 EIM87949.1 - 6e-74 249.2 0.0 8.1e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DEAD PF00270.29 EIM87950.1 - 1.1e-43 149.1 0.2 1.9e-43 148.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM87950.1 - 1.4e-32 112.3 0.0 5.5e-32 110.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EIM87950.1 - 0.00067 20.0 0.1 0.012 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EIM87950.1 - 0.0011 19.1 0.0 0.0023 18.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EIM87950.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EIM87950.1 - 0.079 12.5 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DNA_III_psi PF03603.13 EIM87950.1 - 0.086 13.1 0.1 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III psi subunit AAA_22 PF13401.6 EIM87950.1 - 0.21 11.9 0.6 1.2 9.4 0.6 2.1 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.22 EIM87951.1 - 1.1e-18 66.8 1.6 1.9e-18 66.0 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM87951.1 - 2.5e-08 33.5 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIM87951.1 - 0.035 14.2 0.2 0.067 13.2 0.2 1.5 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 EIM87951.1 - 0.062 13.2 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_8 PF11835.8 EIM87951.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 1 1 2 2 2 0 RRM-like domain PBP PF01161.20 EIM87952.1 - 5e-14 52.7 0.1 7.4e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TPPII_N PF12583.8 EIM87952.1 - 5.2 7.6 12.2 14 6.3 12.2 1.7 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF928 PF06051.12 EIM87955.1 - 0.023 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) DUF761 PF05553.11 EIM87956.1 - 0.19 11.3 2.9 8.4 6.0 0.8 2.2 2 0 0 2 2 2 0 Cotton fibre expressed protein Abhydrolase_1 PF00561.20 EIM87957.1 - 8.3e-40 137.0 0.0 2.1e-39 135.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EIM87957.1 - 0.06 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EIM87957.1 - 0.22 11.3 0.4 1.1 9.0 0.3 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Zn_clus PF00172.18 EIM87958.1 - 7e-15 54.9 26.4 3.5e-07 30.2 10.4 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Snf7 PF03357.21 EIM87959.1 - 3.5e-11 43.0 14.7 5.5e-11 42.4 14.7 1.3 1 1 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 EIM87959.1 - 0.0081 15.8 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Ist1 PF03398.14 EIM87959.1 - 0.013 15.4 4.0 0.02 14.9 4.0 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway SidC_N PF18219.1 EIM87959.1 - 0.045 12.7 2.6 0.056 12.4 2.6 1.3 1 0 0 1 1 1 0 SidC N-terminal domain IML1 PF12257.8 EIM87959.1 - 0.18 10.9 3.1 0.26 10.4 3.1 1.3 1 1 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 Erv26 PF04148.13 EIM87960.1 - 2.7e-59 200.5 0.2 3.2e-59 200.2 0.2 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 EIM87960.1 - 0.029 14.3 0.3 0.074 13.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Pkinase PF00069.25 EIM87961.1 - 0.0035 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 EIM87962.1 - 1.2e-11 44.5 29.4 9.7e-06 25.6 12.3 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Hist_deacetyl PF00850.19 EIM87963.1 - 1.8e-79 267.5 0.0 2.4e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Synaphin PF05835.12 EIM87963.1 - 8.2 6.7 13.6 8.4 6.7 10.0 2.2 2 0 0 2 2 2 0 Synaphin protein Hist_deacetyl PF00850.19 EIM87964.1 - 2.5e-82 276.8 0.0 3.3e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TFIIA PF03153.13 EIM87964.1 - 0.0076 16.3 18.0 0.01 15.9 18.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1256 PF06866.11 EIM87964.1 - 0.22 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) Motilin_ghrelin PF04644.12 EIM87964.1 - 2.7 7.9 5.3 6.6 6.6 5.3 1.6 1 0 0 1 1 1 0 Motilin/ghrelin Xan_ur_permease PF00860.20 EIM87965.1 - 1.5e-59 201.7 34.5 7.5e-58 196.1 34.5 2.1 1 1 0 1 1 1 1 Permease family F-box-like PF12937.7 EIM87966.1 - 1.5e-08 34.4 1.3 1.5e-08 34.4 1.3 2.1 2 0 0 2 2 2 1 F-box-like SBDS PF01172.18 EIM87967.1 - 2.2e-18 66.1 0.0 2.7e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HATPase_c_3 PF13589.6 EIM87968.1 - 2e-09 37.4 0.0 3.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EIM87968.1 - 4.5e-08 32.8 0.0 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EIM87968.1 - 1.6e-05 25.3 0.0 5.5e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EIM87968.1 - 0.0015 18.4 0.0 0.015 15.0 0.0 2.6 2 0 0 2 2 2 1 MutL C terminal dimerisation domain zf-CCCH_4 PF18044.1 EIM87969.1 - 2.6e-05 23.9 2.1 4.6e-05 23.1 2.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Nucleoporin_FG PF13634.6 EIM87969.1 - 0.00016 22.4 183.3 0.013 16.4 26.2 7.8 2 1 2 4 4 4 2 Nucleoporin FG repeat region zf_CCCH_4 PF18345.1 EIM87969.1 - 0.00021 21.2 4.2 0.00036 20.5 4.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EIM87969.1 - 0.0016 18.3 1.3 0.0027 17.6 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.25 EIM87970.1 - 3.7e-64 216.7 0.0 4.7e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM87970.1 - 4.3e-30 104.9 0.0 6.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM87970.1 - 0.0025 16.8 0.2 0.0034 16.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EIM87970.1 - 0.0036 16.2 0.2 0.016 14.0 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EIM87970.1 - 0.026 14.1 0.1 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glyoxal_oxid_N PF07250.11 EIM87971.1 - 2.8e-31 108.5 0.0 5.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM87971.1 - 2.6e-18 66.1 0.8 1.1e-17 64.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 EIM87971.1 - 0.0016 18.4 0.3 2.3 8.3 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 EIM87972.1 - 2e-30 105.7 0.0 3.8e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM87972.1 - 1.3e-17 63.8 0.3 3e-17 62.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 EIM87972.1 - 0.00036 20.5 0.4 2.5 8.2 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain IU_nuc_hydro PF01156.19 EIM87973.1 - 3.3e-83 279.8 0.0 3.8e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FH2 PF02181.23 EIM87974.1 - 2.7e-79 267.0 0.0 3.2e-78 263.4 0.0 2.6 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EIM87974.1 - 7.1e-26 90.9 2.0 2.8e-20 72.7 0.1 3.1 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EIM87974.1 - 9.9e-17 61.2 0.0 9.3e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain DUF3499 PF12005.8 EIM87974.1 - 0.13 12.8 3.9 0.47 11.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3499) ABC_tran_CTD PF16326.5 EIM87974.1 - 0.8 10.0 19.5 0.033 14.4 2.6 4.0 2 1 0 3 3 3 0 ABC transporter C-terminal domain TraC PF07820.12 EIM87974.1 - 2.2 8.7 8.3 0.31 11.4 2.6 2.7 2 0 0 2 2 1 0 TraC-like protein NBP1 PF08537.10 EIM87974.1 - 5.1 6.4 16.8 2.1 7.7 1.7 3.5 2 1 1 3 3 3 0 Fungal Nap binding protein NBP1 DUF5320 PF17253.2 EIM87974.1 - 5.3 8.2 7.2 24 6.1 0.0 3.8 4 0 0 4 4 2 0 Family of unknown function (DUF5320) PKcGMP_CC PF16808.5 EIM87974.1 - 5.5 6.9 17.2 1.8 8.5 0.8 4.8 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Troponin PF00992.20 EIM87974.1 - 5.9 7.2 11.0 0.21 11.9 0.7 2.9 2 1 0 2 2 2 0 Troponin CCDC92 PF14916.6 EIM87974.1 - 6.3 6.6 8.1 20 5.0 2.9 3.0 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Leu_zip PF15294.6 EIM87974.1 - 8.3 5.8 14.4 2.4 7.6 7.9 2.3 2 0 0 2 2 2 0 Leucine zipper Saf_2TM PF18303.1 EIM87975.1 - 0.31 10.6 13.6 0.058 13.0 3.0 3.0 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain adh_short PF00106.25 EIM87976.1 - 9.6e-26 90.4 0.0 3.9e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM87976.1 - 1.4e-11 44.4 0.0 7.4e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM87976.1 - 0.00017 21.6 0.1 0.00067 19.6 0.0 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EIM87976.1 - 0.0023 17.4 0.1 0.0046 16.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MCM PF00493.23 EIM87977.1 - 1.9e-103 344.4 0.1 3.5e-103 343.5 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIM87977.1 - 1.6e-38 131.4 0.0 3.2e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EIM87977.1 - 6.5e-30 103.5 3.0 1.2e-29 102.6 3.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EIM87977.1 - 4.5e-26 91.1 1.1 2.9e-25 88.5 0.8 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EIM87977.1 - 7.5e-23 81.1 0.3 2.7e-22 79.3 0.3 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIM87977.1 - 5.2e-07 29.2 0.0 4.4e-06 26.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EIM87977.1 - 0.0017 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIM87977.1 - 0.0035 17.1 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EIM87977.1 - 0.034 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tom7 PF08038.12 EIM87978.1 - 2.6e-15 55.8 0.0 3.7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 TOM7 family RNF220 PF15926.5 EIM87979.1 - 1.9e-12 47.4 12.5 1.5e-08 34.5 0.2 2.9 3 1 0 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 EIM87979.1 - 7.1e-10 38.6 24.1 1e-09 38.1 14.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM87979.1 - 4e-05 23.4 21.3 0.00019 21.2 13.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM87979.1 - 0.00017 21.5 18.2 0.00065 19.6 12.7 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM87979.1 - 0.0002 21.2 13.8 0.0002 21.2 13.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM87979.1 - 0.0007 19.9 26.0 0.00074 19.8 15.9 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM87979.1 - 0.0024 17.9 7.0 0.0024 17.9 7.0 4.2 4 0 0 4 4 4 2 RING-type zinc-finger zf-RING_6 PF14835.6 EIM87979.1 - 0.0049 16.7 8.7 0.0049 16.7 8.7 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EIM87979.1 - 0.11 12.3 20.5 0.15 12.0 11.8 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Glyco_hydro_3_C PF01915.22 EIM87980.1 - 2e-59 201.0 0.0 1.1e-58 198.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM87980.1 - 2e-49 168.7 0.0 3.1e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM87980.1 - 7.4e-19 67.6 0.1 1.2e-17 63.8 0.1 2.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EIM87980.1 - 2.3e-06 27.5 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF600 PF04634.12 EIM87981.1 - 0.036 14.1 1.2 0.19 11.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF600 Helicase_C PF00271.31 EIM87982.1 - 7.6e-16 58.4 0.0 3.9e-14 52.9 0.0 3.4 4 1 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM87982.1 - 1.3e-14 54.3 0.0 8.7e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EIM87982.1 - 3.7e-13 50.0 4.2 3.7e-13 50.0 4.2 2.0 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 EIM87982.1 - 2.5e-06 27.3 0.3 7.2e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 RQC domain F-box-like PF12937.7 EIM87983.1 - 1.2e-09 37.9 0.1 2.8e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM87983.1 - 0.033 14.6 1.0 3.5 8.2 0.3 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Fe-ADH PF00465.19 EIM87984.1 - 2.3e-58 197.8 0.0 2.9e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EIM87984.1 - 5.3e-08 32.9 0.5 0.00011 22.0 0.1 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EIM87984.1 - 0.042 13.0 0.1 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 3-dehydroquinate synthase Vac14_Fig4_bd PF11916.8 EIM87985.1 - 2.1e-78 262.1 7.1 3.3e-78 261.4 7.1 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EIM87985.1 - 2.8e-41 140.0 0.0 3.2e-37 127.0 0.0 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EIM87985.1 - 1.7e-13 49.6 0.9 0.00061 19.8 0.0 6.9 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EIM87985.1 - 7.4e-08 32.7 0.3 0.18 12.3 0.0 5.4 5 1 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 EIM87985.1 - 3.2e-07 30.6 0.6 0.41 11.1 0.0 5.1 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EIM87985.1 - 5.2e-06 26.6 4.3 0.45 10.5 0.0 4.1 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EIM87985.1 - 0.00061 19.9 0.4 0.42 10.7 0.0 3.3 3 0 0 3 3 3 1 Parkin co-regulated protein UTP25 PF06862.12 EIM87985.1 - 0.035 12.9 0.0 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4106 PF13388.6 EIM87985.1 - 1.4 8.1 14.2 2.3 7.3 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) HPP PF04982.13 EIM87986.1 - 7e-44 148.9 8.1 2.3e-43 147.3 7.0 1.9 2 0 0 2 2 2 1 HPP family Tmemb_14 PF03647.13 EIM87986.1 - 0.013 16.3 10.0 0.048 14.4 6.7 2.6 2 1 0 2 2 2 0 Transmembrane proteins 14C DUF4064 PF13273.6 EIM87986.1 - 0.62 10.4 7.7 1 9.7 4.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4231 PF14015.6 EIM87986.1 - 3.4 8.2 5.4 2.7 8.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Fe-ADH PF00465.19 EIM87987.1 - 8.5e-61 205.8 0.0 1.2e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EIM87987.1 - 4.7e-08 33.0 0.1 0.00038 20.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EIM87987.1 - 0.016 14.4 0.1 0.074 12.2 0.0 1.9 2 0 0 2 2 2 0 3-dehydroquinate synthase Clathrin PF00637.20 EIM87988.1 - 2.5e-23 82.5 0.0 6e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.9 EIM87988.1 - 0.0005 20.5 0.1 0.028 14.9 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 EIM87988.1 - 0.015 15.7 1.3 0.015 15.7 1.3 2.7 3 0 0 3 3 3 0 Ring finger domain zf-RING_5 PF14634.6 EIM87988.1 - 0.048 13.6 3.0 0.28 11.2 3.1 2.2 1 1 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EIM87988.1 - 0.082 12.5 5.6 0.033 13.8 1.9 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EIM87988.1 - 0.95 9.4 5.3 1.2 9.1 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EIM87988.1 - 1.9 8.6 8.5 0.058 13.4 1.8 2.0 2 0 0 2 2 2 0 Zinc-finger zf-RING_11 PF17123.5 EIM87988.1 - 2.1 8.2 4.0 6.4 6.6 4.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger Glyco_hydro_3_C PF01915.22 EIM87989.1 - 1.4e-65 221.1 0.0 2.6e-65 220.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM87989.1 - 6.4e-42 144.0 0.0 1.1e-41 143.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM87989.1 - 1e-23 83.2 0.1 2e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EIM87989.1 - 6.5e-09 35.8 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 PA14 domain DUF3575 PF12099.8 EIM87989.1 - 0.0042 16.4 0.0 0.62 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3575) fn3_2 PF16893.5 EIM87990.1 - 1.4e-37 127.7 0.1 3.1e-37 126.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EIM87990.1 - 3.3e-26 91.0 0.1 5.6e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 EIM87990.1 - 3.1e-08 33.9 0.0 4.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 EIM87990.1 - 9.3e-05 22.7 0.3 0.0003 21.1 0.3 1.9 1 1 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.7 EIM87990.1 - 0.00017 21.5 0.0 0.0016 18.4 0.0 2.2 1 1 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 EIM87990.1 - 0.00026 21.1 0.0 0.0005 20.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EIM87990.1 - 0.0072 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Pox_Ag35 PF03286.14 EIM87990.1 - 0.89 9.3 3.8 1.7 8.4 3.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein EzrA PF06160.12 EIM87992.1 - 0.00075 17.8 8.6 0.001 17.4 8.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FPP PF05911.11 EIM87992.1 - 0.001 17.4 12.9 0.0014 16.9 12.9 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil KASH_CCD PF14662.6 EIM87992.1 - 0.0045 16.8 13.0 0.0091 15.8 13.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 EIM87992.1 - 0.0088 14.2 10.6 0.014 13.6 10.6 1.2 1 0 0 1 1 1 1 HOOK protein YabA PF06156.13 EIM87992.1 - 0.039 14.6 7.0 0.99 10.1 1.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CdvA PF18822.1 EIM87992.1 - 0.18 11.7 8.9 0.15 11.9 3.4 2.6 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Leu_zip PF15294.6 EIM87992.1 - 0.22 11.0 9.0 0.33 10.4 9.0 1.2 1 0 0 1 1 1 0 Leucine zipper HeLo PF14479.6 EIM87992.1 - 0.28 11.0 12.6 1.3 8.8 10.4 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation ING PF12998.7 EIM87992.1 - 0.58 10.8 3.6 0.64 10.6 2.1 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4200 PF13863.6 EIM87992.1 - 1.6 9.2 13.2 3.8 7.9 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4472 PF14739.6 EIM87992.1 - 2 9.2 10.2 0.94 10.2 2.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) BLOC1_2 PF10046.9 EIM87992.1 - 2.6 8.4 7.1 11 6.4 3.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1465 PF07323.12 EIM87992.1 - 3.3 7.6 13.7 0.44 10.4 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DNA_repr_REX1B PF14966.6 EIM87992.1 - 3.5 8.3 7.7 1.7 9.4 1.7 2.3 1 1 1 2 2 2 0 DNA repair REX1-B DUF1664 PF07889.12 EIM87992.1 - 3.9 7.5 5.2 25 4.9 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EIM87992.1 - 5.4 6.2 7.2 3.5 6.8 5.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 EIM87992.1 - 5.8 6.1 18.6 0.41 9.9 4.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EIM87992.1 - 6.4 6.9 6.9 13 6.0 6.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 EIM87992.1 - 8.3 6.7 13.0 2.1 8.6 4.5 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein TPR_MLP1_2 PF07926.12 EIM87992.1 - 8.4 6.5 21.3 12 5.9 3.1 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 EIM87992.1 - 9.8 6.5 6.2 9.5 6.5 3.7 2.2 1 1 1 2 2 2 0 Haemolysin XhlA zf-CCHC PF00098.23 EIM87994.1 - 7.1e-08 32.2 3.0 1.5e-07 31.2 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 EIM87994.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EIM87994.1 - 0.015 15.9 0.0 0.045 14.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EIM87994.1 - 0.032 14.8 0.0 0.082 13.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 EIM87994.1 - 0.04 13.9 0.3 0.17 11.8 0.3 2.1 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EIM87994.1 - 0.063 13.0 6.7 0.13 12.0 6.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EIM87994.1 - 0.076 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2B PF12384.8 EIM87994.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase zf-CCHC_2 PF13696.6 EIM87994.1 - 0.39 10.6 3.2 0.73 9.7 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Tim17 PF02466.19 EIM87997.1 - 0.00067 20.0 5.2 0.035 14.5 0.2 3.6 3 0 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 EIM87997.1 - 0.002 18.7 0.1 0.48 11.0 0.0 2.7 2 0 0 2 2 2 2 N-terminal cysteine-rich region of Transmembrane protein 135 Ribosomal_L7Ae PF01248.26 EIM87998.1 - 7.8e-26 89.6 1.3 9.6e-26 89.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.32 EIM87999.1 - 5.5e-20 71.3 20.7 2.2e-07 31.4 1.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM87999.1 - 1.7e-12 47.5 0.4 7.7e-06 26.1 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIM87999.1 - 0.0012 18.8 4.5 31 4.7 0.0 5.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EIM87999.1 - 0.0012 18.3 0.1 1.2 8.5 0.0 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EIM87999.1 - 0.0012 17.6 2.8 0.17 10.5 1.4 2.9 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 EIM87999.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Frtz PF11768.8 EIM87999.1 - 0.055 11.8 0.0 0.13 10.6 0.0 1.7 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 EIM87999.1 - 0.06 11.3 0.0 0.097 10.6 0.0 1.3 1 0 0 1 1 1 0 IKI3 family eIF2A PF08662.11 EIM87999.1 - 0.16 11.9 0.0 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EIM87999.1 - 0.17 11.2 0.0 17 4.6 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Mitofilin PF09731.9 EIM88000.1 - 3 6.6 6.8 4.9 5.9 6.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein F-box-like PF12937.7 EIM88001.1 - 1.3e-08 34.6 0.3 4.2e-08 33.0 0.3 1.9 1 0 0 1 1 1 1 F-box-like 2OG-FeII_Oxy_2 PF13532.6 EIM88002.1 - 2e-12 47.7 0.0 3.1e-12 47.1 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ubiquitin PF00240.23 EIM88003.1 - 1.1e-25 89.1 0.1 1.3e-25 89.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EIM88003.1 - 1e-12 47.7 0.1 1.1e-12 47.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EIM88003.1 - 1.7e-05 24.6 0.0 2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EIM88003.1 - 0.00075 19.9 0.0 0.00084 19.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain 4HBT PF03061.22 EIM88004.1 - 1.2e-09 38.4 0.2 3.8e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily RelB PF04221.12 EIM88004.1 - 0.052 13.5 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 RelB antitoxin Borrelia_P83 PF05262.11 EIM88005.1 - 0.0073 14.9 31.6 0.0093 14.5 31.6 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein Ham1p_like PF01725.16 EIM88007.1 - 1.6e-58 197.8 0.0 1.7e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family ATG22 PF11700.8 EIM88009.1 - 1.7e-112 376.5 19.4 1.9e-112 376.3 19.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EIM88009.1 - 3.2e-15 55.9 31.5 8.3e-10 38.1 7.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.18 EIM88010.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2997 PF11211.8 EIM88010.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) F-box-like PF12937.7 EIM88011.1 - 7.7e-08 32.1 0.2 1.4e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM88011.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain Consortin_C PF15281.6 EIM88012.1 - 0.32 11.0 1.3 0.66 10.0 0.2 2.0 2 0 0 2 2 2 0 Consortin C-terminus BSP_II PF05432.11 EIM88012.1 - 5.6 6.6 12.8 0.14 11.8 4.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TFIIE-A_C PF11521.8 EIM88012.1 - 8.2 6.8 13.4 4.1 7.8 1.0 3.0 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha CHAT PF12770.7 EIM88013.1 - 5.5e-33 114.6 0.5 8.8e-33 113.9 0.1 1.6 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 EIM88013.1 - 3.9e-20 71.1 47.9 0.013 15.4 0.0 16.0 18 0 0 18 18 18 6 Tetratricopeptide repeat TPR_12 PF13424.6 EIM88013.1 - 4.8e-15 55.6 28.1 0.025 14.9 0.1 12.7 9 3 4 13 13 13 5 Tetratricopeptide repeat TPR_8 PF13181.6 EIM88013.1 - 8.3e-05 22.5 21.2 28 5.3 0.0 12.1 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM88013.1 - 0.00012 21.8 9.7 10 6.4 0.1 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat Sel1 PF08238.12 EIM88013.1 - 0.0021 18.7 5.6 6.3 7.6 0.1 6.8 8 0 0 8 8 7 1 Sel1 repeat TPR_15 PF13429.6 EIM88013.1 - 0.17 11.1 9.9 2.6 7.2 0.1 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM88013.1 - 0.34 11.1 28.9 1.1e+02 3.3 0.0 13.3 16 0 0 16 16 16 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EIM88013.1 - 1.4 9.1 15.0 8.6 6.5 0.0 7.0 8 0 0 8 8 8 0 Exonuclease VII small subunit TPR_14 PF13428.6 EIM88013.1 - 4.5 8.4 23.5 8.6 7.5 0.1 8.8 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM88013.1 - 8.3 6.2 19.3 2.4 7.9 0.3 6.8 10 0 0 10 10 10 0 TPR repeat Arb1 PF09692.10 EIM88014.1 - 0.00032 20.0 0.0 0.016 14.4 0.0 2.7 4 0 0 4 4 4 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 BTB PF00651.31 EIM88016.1 - 0.00029 21.0 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pro_isomerase PF00160.21 EIM88017.1 - 1.1e-37 129.8 0.0 1.6e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EIM88017.1 - 8.3e-16 57.6 0.0 1.4e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EIM88018.1 - 1.2e-25 89.2 11.9 0.0005 20.8 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88018.1 - 8.8e-10 38.8 0.0 0.018 15.3 0.0 4.8 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIM88018.1 - 0.019 14.3 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain PHD PF00628.29 EIM88019.1 - 4.4e-07 29.7 14.5 6.4e-07 29.2 5.3 2.7 2 1 0 2 2 2 2 PHD-finger zf-HC5HC2H_2 PF13832.6 EIM88019.1 - 0.13 12.4 5.6 0.21 11.7 1.0 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-MIZ PF02891.20 EIM88019.1 - 0.4 10.5 7.0 0.063 13.0 2.3 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-trcl PF13451.6 EIM88019.1 - 0.79 9.7 4.2 7.9 6.5 0.3 2.6 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-PHD-like PF15446.6 EIM88019.1 - 1.1 8.9 7.8 5.3 6.6 0.0 3.1 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 EIM88019.1 - 1.2 9.3 11.0 0.1 12.7 4.5 2.4 2 0 0 2 2 2 0 PHD-finger Elf1 PF05129.13 EIM88019.1 - 2.8 8.1 8.6 3.5 7.8 0.6 3.3 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Tocopherol_cycl PF14249.6 EIM88020.1 - 0.0024 17.1 0.0 0.043 12.9 0.0 2.1 2 0 0 2 2 2 2 Tocopherol cyclase Arb1 PF09692.10 EIM88022.1 - 0.00042 19.6 0.0 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF596 PF04591.12 EIM88022.1 - 0.084 13.0 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF596 FXMRP1_C_core PF12235.8 EIM88022.1 - 0.2 12.3 2.7 0.48 11.1 2.7 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Aldedh PF00171.22 EIM88023.1 - 5.2e-107 358.2 0.0 6.3e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Myb_DNA-binding PF00249.31 EIM88024.1 - 1.7e-21 76.2 7.8 2.7e-11 43.5 0.2 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIM88024.1 - 1.3e-14 54.2 9.2 2e-08 34.3 0.4 4.1 3 1 2 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EIM88024.1 - 0.00072 19.9 1.0 0.00072 19.9 1.0 3.7 3 2 2 5 5 5 1 Myb/SANT-like DNA-binding domain F-box-like PF12937.7 EIM88025.1 - 5.9e-09 35.7 0.2 1.4e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like Sec15 PF04091.12 EIM88026.1 - 7.5e-97 324.5 2.1 7.5e-97 324.5 2.1 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 EIM88026.1 - 4.3e-07 29.9 0.3 2.2e-06 27.6 0.1 2.4 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 EIM88026.1 - 0.00051 20.2 0.2 0.00051 20.2 0.2 3.3 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 EIM88026.1 - 0.0034 17.3 5.3 0.047 13.6 0.3 3.6 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 EIM88026.1 - 0.0045 17.1 4.3 0.011 15.8 0.3 3.2 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 EIM88026.1 - 0.17 11.9 2.6 0.42 10.6 0.0 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACP_PD PF04336.12 EIM88026.1 - 0.46 10.9 4.1 2.9 8.4 0.1 4.0 5 0 0 5 5 5 0 Acyl carrier protein phosphodiesterase NPV_P10 PF05531.12 EIM88026.1 - 0.52 10.8 4.2 2 8.9 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.6 EIM88026.1 - 1.1 9.6 4.9 1.5 9.2 2.3 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Arf PF00025.21 EIM88027.1 - 5.3e-79 263.7 0.1 6.1e-79 263.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIM88027.1 - 1.5e-14 53.9 0.0 1.8e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EIM88027.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EIM88027.1 - 6.6e-13 48.5 1.3 4.3e-09 36.0 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EIM88027.1 - 8.4e-13 48.2 0.0 9.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EIM88027.1 - 1.1e-10 41.3 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIM88027.1 - 2.5e-06 27.6 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EIM88027.1 - 0.007 15.7 0.7 0.02 14.2 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Lactamase_B_2 PF12706.7 EIM88029.1 - 3.3e-29 101.8 0.0 4.7e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EIM88029.1 - 1.1e-06 28.6 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIM88029.1 - 0.0084 16.1 2.8 0.056 13.4 1.3 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Nup188 PF10487.9 EIM88030.1 - 7.5e-33 113.5 0.0 1.1e-16 60.1 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EIM88030.1 - 2.5e-08 33.2 0.1 5.6e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup192 PF11894.8 EIM88030.1 - 0.06 10.5 0.7 0.18 8.9 0.0 2.1 3 0 0 3 3 3 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 OppC_N PF12911.7 EIM88031.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3149 PF11346.8 EIM88031.1 - 0.33 10.6 1.4 0.59 9.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TFIIA PF03153.13 EIM88031.1 - 0.51 10.3 25.5 0.27 11.2 10.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 EIM88031.1 - 1.9 6.9 19.6 2.8 6.4 19.6 1.1 1 0 0 1 1 1 0 Utp14 protein Adap_comp_sub PF00928.21 EIM88032.1 - 4.1e-23 82.1 0.0 6.4e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIM88032.1 - 4.4e-07 29.9 0.1 6.6e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4337 PF14235.6 EIM88032.1 - 0.19 11.9 0.7 0.3 11.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Phytoreo_Pns PF05451.11 EIM88032.1 - 0.19 10.9 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Cep57_CLD_2 PF14197.6 EIM88034.1 - 0.0026 17.8 7.2 0.0079 16.3 1.2 2.4 1 1 1 2 2 2 2 Centrosome localisation domain of PPC89 DUF4164 PF13747.6 EIM88034.1 - 0.011 16.0 9.3 0.021 15.1 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF2046 PF09755.9 EIM88034.1 - 0.017 14.3 1.7 0.03 13.6 1.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) bZIP_1 PF00170.21 EIM88034.1 - 0.23 11.6 1.3 3.8 7.7 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 EIM88034.1 - 7 7.2 6.7 15 6.1 6.6 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Swi5 PF07061.11 EIM88035.1 - 8.6e-23 80.2 3.4 1.1e-22 79.9 3.4 1.0 1 0 0 1 1 1 1 Swi5 Lzipper-MIP1 PF14389.6 EIM88035.1 - 0.0066 16.7 1.7 0.0078 16.5 1.7 1.3 1 1 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Macoilin PF09726.9 EIM88035.1 - 0.0066 15.1 1.9 0.0074 14.9 1.9 1.0 1 0 0 1 1 1 1 Macoilin family Sec2p PF06428.11 EIM88035.1 - 0.01 15.8 1.6 0.014 15.4 1.6 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Tn7_Tnp_TnsA_C PF08721.11 EIM88035.1 - 0.02 15.5 0.6 0.059 14.0 0.1 1.8 1 1 1 2 2 2 0 TnsA endonuclease C terminal UBA_6 PF18039.1 EIM88035.1 - 0.041 13.8 0.9 0.82 9.6 0.3 2.2 2 0 0 2 2 2 0 UBA-like domain Med21 PF11221.8 EIM88035.1 - 0.057 13.7 5.3 0.051 13.8 3.9 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF5486 PF17588.2 EIM88035.1 - 0.066 13.1 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) RCC1 PF00415.18 EIM88036.1 - 3.1e-25 88.6 21.9 2.3e-07 31.3 3.4 7.6 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIM88036.1 - 6.6e-06 25.8 40.1 0.00037 20.2 0.4 7.7 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat OPT PF03169.15 EIM88038.1 - 7e-132 441.2 48.6 7.9e-132 441.0 48.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Plavaka PF18759.1 EIM88041.1 - 3.5e-117 391.3 0.0 4.5e-117 390.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase RNA_pol_Rpb1_5 PF04998.17 EIM88042.1 - 2.2e-82 276.5 0.0 6.5e-82 275.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EIM88042.1 - 1.8e-65 220.2 0.1 3e-65 219.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EIM88042.1 - 2.8e-37 128.1 0.0 5.7e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EIM88042.1 - 2.7e-31 109.1 1.5 1.5e-24 87.0 0.0 3.0 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EIM88042.1 - 2.8e-21 75.5 0.0 8.4e-21 73.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 AA_permease PF00324.21 EIM88043.1 - 1e-108 364.0 41.5 1.3e-108 363.7 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM88043.1 - 9.8e-33 113.6 42.3 1.4e-32 113.0 42.3 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 EIM88045.1 - 4.1e-42 144.4 0.0 1.2e-23 83.8 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88045.1 - 2.3e-12 46.8 0.0 3.4e-09 36.4 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIM88045.1 - 6.5e-05 23.0 1.0 0.00027 21.0 1.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EIM88045.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRN3 PF05327.11 EIM88045.1 - 1.1 7.7 6.3 1.7 7.1 6.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EIM88045.1 - 2.1 6.5 8.8 4.4 5.5 8.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Pneumo_att_G PF05539.11 EIM88045.1 - 3.1 7.3 10.1 5.7 6.4 10.1 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G NUDIX PF00293.28 EIM88046.1 - 4.2e-12 46.2 0.0 8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF3446 PF11928.8 EIM88047.1 - 0.1 12.9 2.9 0.16 12.3 2.9 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain Chitin_synth_2 PF03142.15 EIM88048.1 - 4.6e-239 794.4 0.3 6e-239 794.0 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EIM88048.1 - 5.9e-103 345.4 0.0 2.6e-102 343.2 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EIM88048.1 - 2.9e-16 59.3 0.2 2e-12 47.1 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EIM88048.1 - 1.1e-15 57.3 0.5 4.2e-15 55.4 0.1 2.3 3 0 0 3 3 3 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 EIM88048.1 - 1.1e-13 51.6 0.0 2.8e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EIM88048.1 - 4.3e-13 49.6 4.7 4.3e-13 49.6 4.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EIM88048.1 - 3.5e-07 30.2 0.0 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIM88048.1 - 0.00057 19.4 0.0 0.0082 15.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Coatomer_WDAD PF04053.14 EIM88049.1 - 1.1e-148 496.0 0.0 2.3e-148 495.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EIM88049.1 - 2e-37 126.5 7.9 1.7e-06 28.7 0.1 8.6 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88049.1 - 6.9e-09 35.9 0.1 0.0073 16.6 0.0 6.1 3 2 4 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EIM88049.1 - 0.00028 20.9 0.0 14 5.8 0.0 4.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EIM88049.1 - 0.001 17.8 0.3 0.35 9.5 0.1 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 LigD_N PF13298.6 EIM88049.1 - 0.0011 19.2 0.0 2.4 8.5 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase Ligase (LigD) Prok-E2_D PF14460.6 EIM88051.1 - 0.33 10.6 2.7 13 5.4 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic E2 family D CPBP PF02517.16 EIM88052.1 - 1e-13 51.4 6.3 1e-13 51.4 6.3 2.7 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Band_7 PF01145.25 EIM88053.1 - 4.2e-23 82.3 4.3 7.5e-23 81.4 4.3 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family ZnuA PF01297.17 EIM88053.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Acetyltransf_10 PF13673.7 EIM88054.1 - 1e-09 38.4 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM88054.1 - 2.3e-09 37.5 0.0 3.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM88054.1 - 2e-06 28.0 0.0 2.9e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EIM88054.1 - 0.00013 22.0 0.0 0.00035 20.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM88054.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EIM88054.1 - 0.0089 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Questin_oxidase PF14027.6 EIM88055.1 - 2.1e-78 264.2 0.0 2.5e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like DUF5567 PF17722.1 EIM88056.1 - 0.0083 16.0 0.3 0.016 15.1 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5567) Pkinase PF00069.25 EIM88057.1 - 7.5e-48 163.2 0.0 1e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88057.1 - 3.1e-26 92.2 0.0 4e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM88057.1 - 0.00061 19.8 0.0 0.02 14.8 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM88057.1 - 0.016 14.6 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM88057.1 - 0.017 14.4 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EIM88057.1 - 0.044 12.6 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Iso_dh PF00180.20 EIM88058.1 - 5.3e-79 265.9 0.0 6.5e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosom_S30AE_C PF16321.5 EIM88059.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Acetyltransf_1 PF00583.25 EIM88060.1 - 9.6e-12 45.2 0.0 1.1e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM88060.1 - 4.4e-09 36.4 0.1 5e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM88060.1 - 1.3e-05 25.5 0.0 1.8e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM88060.1 - 6.6e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EIM88060.1 - 0.00087 18.8 1.6 0.002 17.6 0.2 2.0 2 1 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EIM88060.1 - 0.012 15.7 0.2 0.019 15.0 0.2 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2052 PF09747.9 EIM88061.1 - 0.2 11.7 14.6 0.8 9.8 14.6 2.0 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Lipase_GDSL PF00657.22 EIM88062.1 - 0.0045 17.0 0.0 0.0067 16.4 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LSM PF01423.22 EIM88063.1 - 2.1e-19 69.0 0.0 2.3e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2034 PF10356.9 EIM88063.1 - 0.062 12.7 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DUF150_C PF17384.2 EIM88063.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Chitin_synth_1 PF01644.17 EIM88064.1 - 4.4e-66 221.9 0.0 7.4e-66 221.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIM88064.1 - 2.1e-26 91.7 0.1 4.2e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIM88064.1 - 1.2e-24 86.9 0.0 4.5e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIM88064.1 - 3.4e-07 30.4 8.4 6.8e-06 26.1 8.3 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 zf-C3HC4 PF00097.25 EIM88065.1 - 1.3e-07 31.4 0.6 3.7e-07 29.9 0.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM88065.1 - 2.2e-07 30.6 2.9 1.3e-05 24.9 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM88065.1 - 9.1e-07 28.6 2.2 0.00013 21.8 0.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EIM88065.1 - 1.8e-06 28.1 3.3 0.00012 22.3 1.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM88065.1 - 2.8e-06 27.2 0.7 7.4e-06 25.9 0.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM88065.1 - 2e-05 24.3 0.8 0.00078 19.3 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM88065.1 - 0.00023 21.4 3.7 0.00096 19.4 3.8 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EIM88065.1 - 0.0022 17.9 3.7 0.023 14.6 4.2 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 EIM88065.1 - 0.014 15.2 0.9 0.059 13.2 0.9 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 EIM88065.1 - 0.017 15.2 0.4 0.057 13.5 0.1 1.9 1 1 0 2 2 2 0 Zinc-binding RING-finger zf-C2HC5 PF06221.13 EIM88065.1 - 0.041 13.9 0.8 0.75 9.8 0.1 2.2 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Zn-C2H2_12 PF18112.1 EIM88065.1 - 0.041 14.3 1.1 6.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 EIM88065.1 - 0.042 13.9 0.4 0.15 12.1 0.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EIM88065.1 - 0.042 13.6 0.3 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EIM88065.1 - 0.07 13.3 4.8 0.18 12.0 0.7 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 EIM88065.1 - 0.088 12.7 0.4 12 5.8 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-met2 PF12907.7 EIM88065.1 - 0.095 12.9 0.8 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding Baculo_IE-1 PF05290.11 EIM88065.1 - 0.1 12.5 0.3 0.53 10.2 0.2 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zinc_ribbon_9 PF14369.6 EIM88065.1 - 0.11 12.8 1.8 12 6.2 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon UBZ_FAAP20 PF15750.5 EIM88065.1 - 0.17 11.8 2.4 7.9 6.5 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Spo12 PF05032.12 EIM88066.1 - 9.6e-14 51.0 1.1 9.6e-14 51.0 1.1 1.8 2 0 0 2 2 2 1 Spo12 family Cwf_Cwc_15 PF04889.12 EIM88066.1 - 0.0095 15.7 0.5 0.011 15.5 0.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3245 PF11595.8 EIM88066.1 - 0.022 15.2 1.3 0.031 14.8 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF3246 PF11596.8 EIM88066.1 - 0.14 11.6 4.6 0.17 11.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ras PF00071.22 EIM88068.1 - 6e-45 152.7 0.4 6.9e-45 152.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM88068.1 - 9.8e-14 51.6 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM88068.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM88068.1 - 7.7e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM88068.1 - 0.00026 21.0 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EIM88068.1 - 0.00035 20.0 0.1 0.00041 19.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EIM88068.1 - 0.007 16.4 0.0 0.0088 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EIM88068.1 - 0.012 15.2 0.3 0.048 13.2 0.3 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EIM88068.1 - 0.021 14.3 0.1 0.26 10.8 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 EIM88068.1 - 0.076 12.9 0.3 0.091 12.7 0.3 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mannosidase_ig PF17786.1 EIM88069.1 - 7.2e-19 68.2 0.1 2.6e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EIM88069.1 - 4e-09 37.1 0.1 9.8e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EIM88069.1 - 0.024 14.4 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Ig-fold domain Glyco_hydro_2_C PF02836.17 EIM88069.1 - 0.027 13.6 0.1 0.098 11.7 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EIM88069.1 - 0.055 13.4 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Piwi PF02171.17 EIM88070.1 - 1.5e-87 293.7 0.0 2.2e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EIM88070.1 - 1.7e-23 83.8 0.0 3.7e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EIM88070.1 - 2.7e-18 65.3 0.0 6.1e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EIM88070.1 - 1.4e-14 54.1 0.1 3.3e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EIM88070.1 - 3.8e-12 46.3 0.1 1.1e-11 44.8 0.1 1.9 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 EIM88070.1 - 8e-08 32.2 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Histidinol_dh PF00815.20 EIM88071.1 - 8e-162 538.9 0.9 1e-161 538.5 0.9 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EIM88071.1 - 1.2e-24 86.0 0.2 2.1e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EIM88071.1 - 1.5e-11 44.6 0.4 3.6e-11 43.4 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Transket_pyr PF02779.24 EIM88072.1 - 4e-47 160.2 0.0 6.3e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIM88072.1 - 1.7e-43 147.4 0.1 3.1e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EIM88072.1 - 0.0017 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II adh_short PF00106.25 EIM88073.1 - 3.4e-36 124.5 0.0 4.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM88073.1 - 2.6e-31 109.0 0.0 3.1e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM88073.1 - 1.7e-12 47.6 0.1 4.5e-12 46.2 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM88073.1 - 6.9e-05 22.4 0.0 0.00023 20.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM88073.1 - 0.0014 18.5 0.1 0.0021 18.0 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding YjeF_N PF03853.15 EIM88073.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF1776 PF08643.10 EIM88073.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Amidohydro_2 PF04909.14 EIM88074.1 - 5.1e-16 59.3 0.0 2e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Collagen_mid PF15984.5 EIM88074.1 - 0.036 13.8 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial collagen, middle region DUF3140 PF11338.8 EIM88075.1 - 2.8e-25 88.6 0.6 2.8e-25 88.6 0.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 EIM88075.1 - 0.082 13.4 0.7 0.22 12.0 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Raptor_N PF14538.6 EIM88076.1 - 3.5e-62 208.7 0.0 6.2e-62 207.9 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EIM88076.1 - 2.2e-10 40.9 3.5 0.0068 17.2 0.7 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88076.1 - 7.4e-06 26.2 0.1 1.6 9.1 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 EIM88076.1 - 6.9e-05 22.8 0.0 0.00069 19.7 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.6 EIM88076.1 - 0.00045 20.7 0.1 0.0022 18.5 0.0 2.3 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 EIM88076.1 - 0.0057 17.0 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats Lactamase_B_6 PF16661.5 EIM88077.1 - 6.6e-50 169.2 0.0 1.6e-49 167.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EIM88077.1 - 2.1e-25 89.9 9.2 8.4e-25 87.9 0.0 4.2 4 1 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EIM88077.1 - 3.7e-19 69.0 0.0 6.6e-18 65.0 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EIM88077.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EIM88077.1 - 0.12 11.9 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Raptor_N PF14538.6 EIM88078.1 - 2.3e-42 144.4 0.0 4.6e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EIM88078.1 - 9.3e-06 26.3 6.8 0.42 11.6 0.4 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 EIM88078.1 - 7.2e-05 22.7 0.6 0.0089 16.2 0.0 3.2 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.6 EIM88078.1 - 0.00039 20.9 0.0 0.0056 17.2 0.0 2.7 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 EIM88078.1 - 0.015 15.7 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats Cnd1 PF12717.7 EIM88078.1 - 0.043 13.8 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Peptidase_C14 PF00656.22 EIM88078.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Caspase domain p450 PF00067.22 EIM88079.1 - 5.9e-62 209.9 0.0 2.6e-61 207.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EIM88080.1 - 5.3e-13 49.1 0.0 8.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM88080.1 - 6e-06 26.1 0.0 2e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 EIM88080.1 - 0.0037 17.2 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EIM88080.1 - 0.027 13.9 0.2 0.05 13.0 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GPI-anchored PF10342.9 EIM88081.1 - 7.7e-13 49.0 4.0 7.7e-13 49.0 4.0 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAP1 PF07218.11 EIM88081.1 - 1.6 7.0 15.6 1.5 7.0 15.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NUDE_C PF04880.13 EIM88081.1 - 6 7.3 9.2 9.3 6.7 9.2 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FSA_C PF10479.9 EIM88081.1 - 9.9 4.2 14.5 11 4.0 14.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus QRPTase_C PF01729.19 EIM88082.1 - 4.7e-49 166.4 0.0 5.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EIM88082.1 - 2.5e-19 69.1 0.1 7.7e-19 67.5 0.1 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SIP1 PF04938.12 EIM88083.1 - 6.7e-27 94.6 0.0 9.4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF5102 PF17104.5 EIM88084.1 - 1.5e-64 218.8 0.1 2.1e-64 218.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Ribosomal_L2_C PF03947.18 EIM88085.1 - 1.1e-49 167.9 1.8 1.7e-49 167.2 1.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EIM88085.1 - 3.7e-23 81.3 0.8 6.7e-23 80.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RIX1 PF08167.12 EIM88086.1 - 2.6e-34 118.6 6.9 2e-33 115.7 3.7 2.5 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis RNA_pol_I_TF PF04090.12 EIM88087.1 - 5.8e-12 45.5 0.5 1.5e-09 37.6 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TIP49 PF06068.13 EIM88089.1 - 1.2e-157 524.7 1.0 1.7e-157 524.2 1.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EIM88089.1 - 3.9e-22 78.1 0.9 2.7e-21 75.5 1.3 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EIM88089.1 - 8.1e-09 36.0 0.4 1.1e-05 25.8 0.1 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EIM88089.1 - 3.7e-06 26.8 0.2 0.0049 16.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EIM88089.1 - 5.5e-05 22.6 0.5 0.00011 21.7 0.5 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EIM88089.1 - 6.8e-05 23.3 0.1 0.00036 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EIM88089.1 - 0.0012 18.3 1.1 0.036 13.5 0.3 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIM88089.1 - 0.0035 17.3 1.3 7.5 6.5 0.1 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM88089.1 - 0.0062 16.8 0.2 0.28 11.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 EIM88089.1 - 0.016 14.8 0.3 0.052 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EIM88089.1 - 0.046 14.1 5.7 0.13 12.6 1.3 3.1 2 1 0 2 2 2 0 AAA domain TFIID_20kDa PF03847.13 EIM88089.1 - 0.11 13.1 0.1 0.31 11.6 0.1 1.8 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Sec10 PF07393.11 EIM88090.1 - 2.2e-224 747.1 0.0 3.5e-224 746.4 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1664 PF07889.12 EIM88090.1 - 0.055 13.5 0.2 0.2 11.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Peptidase_S46 PF10459.9 EIM88090.1 - 0.055 12.1 3.6 0.11 11.1 3.2 1.8 1 1 1 2 2 2 0 Peptidase S46 I_LWEQ PF01608.17 EIM88090.1 - 0.083 13.1 0.4 0.24 11.6 0.4 1.9 1 1 0 1 1 1 0 I/LWEQ domain GP24_25 PF17388.2 EIM88090.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 ECH_1 PF00378.20 EIM88091.1 - 2.9e-57 193.8 0.0 3.3e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIM88091.1 - 1.5e-25 90.4 0.0 8.7e-25 87.9 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF4287 PF14117.6 EIM88092.1 - 0.085 13.0 0.1 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) BTB PF00651.31 EIM88093.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain FOXP-CC PF16159.5 EIM88095.1 - 0.00014 22.4 11.0 0.015 15.9 0.4 3.9 1 1 2 3 3 3 3 FOXP coiled-coil domain Methyltransf_23 PF13489.6 EIM88096.1 - 1.5e-17 63.9 0.0 2.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM88096.1 - 2.3e-14 53.8 0.0 4.4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM88096.1 - 2.2e-12 47.5 0.0 4.8e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM88096.1 - 9e-12 45.6 0.0 1.9e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM88096.1 - 6.6e-09 35.7 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM88096.1 - 1.8e-05 24.2 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EIM88096.1 - 0.0038 16.8 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EIM88096.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EIM88096.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 EIM88096.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 EIM88096.1 - 0.06 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 EIM88096.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Abhydrolase_2 PF02230.16 EIM88097.1 - 1.8e-55 188.1 0.0 2.3e-54 184.5 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EIM88097.1 - 5.3e-07 29.1 0.1 0.0052 16.1 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM88097.1 - 3.8e-05 24.4 1.8 6.1e-05 23.7 1.9 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM88097.1 - 0.00045 19.9 0.7 0.51 9.9 0.1 3.1 2 1 1 3 3 3 2 alpha/beta hydrolase fold Esterase PF00756.20 EIM88097.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 EIM88097.1 - 0.17 11.7 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EIM88097.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Copper-bind PF00127.20 EIM88098.1 - 0.084 13.3 0.0 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family RNA_pol_Rpb2_6 PF00562.28 EIM88099.1 - 1.3e-110 370.1 0.0 2.1e-110 369.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EIM88099.1 - 2.2e-35 122.0 0.0 3.4e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EIM88099.1 - 7.4e-28 96.5 0.0 1.7e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EIM88099.1 - 2.4e-23 81.9 0.0 5.2e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EIM88099.1 - 2e-20 73.3 0.0 6.4e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EIM88099.1 - 6.5e-19 68.1 0.0 5.7e-15 55.5 0.0 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 Nucleoporin2 PF04096.14 EIM88100.1 - 1.6e-46 158.1 0.0 2.9e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EIM88100.1 - 2.1e-20 73.3 289.0 4.2e-07 30.7 32.8 9.8 4 3 4 8 8 8 6 Nucleoporin FG repeat region Yae1_N PF09811.9 EIM88101.1 - 0.019 14.7 3.1 0.03 14.0 3.1 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal TPR_19 PF14559.6 EIM88101.1 - 0.31 11.6 6.7 0.57 10.7 6.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 EIM88102.1 - 1.2e-07 31.8 10.4 5.5e-05 23.4 3.5 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EIM88102.1 - 4.8e-06 26.7 14.1 0.00014 22.1 4.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM88102.1 - 0.0033 18.1 2.1 0.0033 18.1 2.1 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-Dof PF02701.15 EIM88102.1 - 0.0068 16.5 3.1 0.011 15.9 1.2 2.1 2 0 0 2 2 2 1 Dof domain, zinc finger zf-met PF12874.7 EIM88102.1 - 0.013 15.9 1.9 0.013 15.9 1.9 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Metallophos PF00149.28 EIM88103.1 - 3.7e-36 125.5 0.1 5.8e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIM88103.1 - 0.0079 16.6 1.4 0.018 15.5 1.4 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EIM88103.1 - 0.094 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 EIM88103.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Yae1_N PF09811.9 EIM88104.1 - 0.18 11.5 3.3 0.34 10.7 3.3 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal ABC_tran PF00005.27 EIM88105.1 - 4.5e-46 156.8 0.2 1.6e-22 80.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EIM88105.1 - 1.1e-20 73.4 3.5 5e-20 71.3 3.5 2.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIM88105.1 - 6.3e-13 49.2 8.7 0.0049 16.7 0.2 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIM88105.1 - 3.4e-09 37.5 3.2 0.0017 18.9 0.0 3.9 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.19 EIM88105.1 - 9.8e-09 35.0 1.7 0.68 9.3 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIM88105.1 - 1.9e-08 33.9 0.1 0.0025 17.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EIM88105.1 - 3.8e-08 33.9 0.0 0.00037 20.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM88105.1 - 1.8e-06 27.9 1.3 0.0033 17.3 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EIM88105.1 - 8.6e-06 25.8 0.0 0.012 15.7 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EIM88105.1 - 1.2e-05 25.4 0.1 0.066 13.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 EIM88105.1 - 2.3e-05 24.2 0.0 0.009 15.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM88105.1 - 0.00024 21.4 0.2 1.1 9.6 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EIM88105.1 - 0.00032 21.0 0.0 0.026 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EIM88105.1 - 0.00058 19.7 12.3 0.3 10.7 1.0 4.7 2 2 2 4 4 4 2 AAA ATPase domain AAA_24 PF13479.6 EIM88105.1 - 0.0006 19.6 0.8 2.2 8.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EIM88105.1 - 0.0011 19.6 0.1 0.64 10.6 0.0 3.3 3 1 1 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 EIM88105.1 - 0.0012 18.2 0.4 0.48 9.7 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.14 EIM88105.1 - 0.0015 18.5 0.1 8.7 6.3 0.1 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EIM88105.1 - 0.0024 18.2 1.5 3.1 8.2 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Dynamin_N PF00350.23 EIM88105.1 - 0.0031 17.6 9.8 0.58 10.2 0.2 4.4 2 2 1 3 3 3 2 Dynamin family DUF87 PF01935.17 EIM88105.1 - 0.0033 17.5 5.2 0.84 9.7 0.1 3.9 4 1 1 5 5 4 2 Helicase HerA, central domain AAA_33 PF13671.6 EIM88105.1 - 0.0063 16.7 0.1 6.8 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 EIM88105.1 - 0.0072 16.4 0.0 9.8 6.2 0.0 3.8 5 0 0 5 5 4 0 AAA domain AAA PF00004.29 EIM88105.1 - 0.0084 16.5 2.6 6.4 7.2 0.3 3.8 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EIM88105.1 - 0.0096 15.1 1.5 2 7.5 0.0 3.1 3 1 0 3 3 3 1 G-protein alpha subunit ATP-synt_ab PF00006.25 EIM88105.1 - 0.011 15.4 0.9 0.59 9.8 0.0 2.9 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EIM88105.1 - 0.013 14.7 0.0 2.7 7.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EIM88105.1 - 0.013 15.0 0.1 11 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EIM88105.1 - 0.019 15.2 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 EIM88105.1 - 0.02 14.1 0.8 4.7 6.3 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 EIM88105.1 - 0.02 14.8 2.6 3.1 7.7 0.2 3.5 4 0 0 4 4 3 0 NTPase Arf PF00025.21 EIM88105.1 - 0.023 14.2 0.3 0.51 9.8 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family KAP_NTPase PF07693.14 EIM88105.1 - 0.035 13.3 0.2 7.3 5.7 0.0 2.5 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.26 EIM88105.1 - 0.039 13.6 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_27 PF13514.6 EIM88105.1 - 0.048 13.2 0.1 12 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2730 PF10805.8 EIM88105.1 - 0.05 13.7 0.3 0.19 11.8 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2730) TsaE PF02367.17 EIM88105.1 - 0.059 13.4 0.4 13 5.8 0.0 3.4 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 EIM88105.1 - 0.063 12.8 0.0 0.52 9.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 EIM88105.1 - 0.072 12.6 0.9 7.8 6.0 0.0 3.1 4 0 0 4 4 3 0 P-loop containing dynein motor region AAA_17 PF13207.6 EIM88105.1 - 0.18 12.2 1.0 15 6.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_13 PF13166.6 EIM88105.1 - 0.23 10.1 5.3 1.2 7.7 0.0 3.3 4 0 0 4 4 4 0 AAA domain Pox_A32 PF04665.12 EIM88105.1 - 1.2 8.5 5.3 7.2 6.0 0.0 3.3 3 1 0 3 3 3 0 Poxvirus A32 protein DivIC PF04977.15 EIM88105.1 - 1.5 8.6 6.8 6.9 6.5 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator PTPRCAP PF15713.5 EIM88106.1 - 0.013 15.8 13.5 0.013 15.8 13.5 2.6 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated FAM72 PF14976.6 EIM88106.1 - 0.65 10.1 2.8 1.1 9.4 2.8 1.3 1 0 0 1 1 1 0 FAM72 protein NPR3 PF03666.13 EIM88106.1 - 4.2 6.1 11.2 9.3 4.9 11.2 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gln-synt_C PF00120.24 EIM88107.1 - 3.8e-17 62.3 0.0 4.2e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EIM88107.1 - 1.2e-12 47.4 0.0 1.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DnaJ PF00226.31 EIM88108.1 - 6.3e-16 58.3 0.0 1.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.13 EIM88108.1 - 0.046 14.3 0.0 1.5 9.5 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-RRN7 PF11781.8 EIM88109.1 - 0.034 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nop14 PF04147.12 EIM88109.1 - 0.18 10.0 15.6 0.28 9.3 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EIM88109.1 - 0.65 8.7 5.1 0.96 8.2 5.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 EIM88109.1 - 4.2 5.8 7.5 6.3 5.2 7.5 1.2 1 0 0 1 1 1 0 Macoilin family Clat_adaptor_s PF01217.20 EIM88111.1 - 2.1e-56 189.8 2.0 2.5e-56 189.6 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain EloA-BP1 PF15870.5 EIM88112.1 - 1.2e-07 32.2 0.1 2.1e-06 28.1 0.1 2.2 1 1 1 2 2 2 1 ElonginA binding-protein 1 RNase_T PF00929.24 EIM88112.1 - 1.2e-05 25.9 0.0 1.9e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.12 EIM88112.1 - 0.52 11.1 3.3 1.1 10.0 3.3 1.6 1 0 0 1 1 1 0 CHORD Histone PF00125.24 EIM88115.1 - 2.6e-43 147.5 1.1 2.6e-43 147.5 1.1 1.5 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EIM88115.1 - 0.0043 17.4 0.1 0.007 16.7 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EIM88115.1 - 0.0061 16.7 0.1 0.012 15.8 0.1 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 EIM88115.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TRAM_LAG1_CLN8 PF03798.16 EIM88116.1 - 4e-34 118.1 25.7 4e-34 118.1 25.7 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EIM88116.1 - 9.8e-20 70.0 0.4 9.8e-20 70.0 0.4 2.1 2 0 0 2 2 2 1 TRAM1-like protein ThrE PF06738.12 EIM88118.1 - 1.4e-42 145.7 8.4 1.4e-42 145.7 8.4 2.3 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM88118.1 - 1.1e-06 28.9 9.7 1.1e-06 28.9 9.7 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE CsbD PF05532.12 EIM88119.1 - 0.012 15.5 3.4 0.031 14.2 3.4 1.8 1 0 0 1 1 1 0 CsbD-like DUF2183 PF09949.9 EIM88120.1 - 8.4e-24 83.8 0.1 1.9e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) GRP PF07172.11 EIM88121.1 - 0.21 12.3 10.7 0.46 11.2 10.7 1.5 1 0 0 1 1 1 0 Glycine rich protein family LSM PF01423.22 EIM88122.1 - 3.3e-20 71.6 0.0 3.6e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EIM88122.1 - 0.028 14.1 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Hfq protein MFS_1 PF07690.16 EIM88123.1 - 1.7e-32 112.7 26.3 2.2e-32 112.4 26.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4272 PF14094.6 EIM88123.1 - 0.048 12.9 0.2 0.84 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) Glyco_hydro_88 PF07470.13 EIM88124.1 - 3e-90 302.8 0.4 3.4e-90 302.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 EIM88124.1 - 0.011 15.0 0.1 0.11 11.7 0.1 2.3 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Nop PF01798.18 EIM88125.1 - 3.3e-73 246.0 0.0 5.3e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EIM88125.1 - 4.5e-41 140.5 4.6 9.5e-41 139.5 4.6 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain NifU_N PF01592.16 EIM88126.1 - 3.7e-53 179.1 0.1 8.2e-53 178.0 0.0 1.5 1 1 1 2 2 2 1 NifU-like N terminal domain TFIID-31kDa PF02291.15 EIM88127.1 - 1.7e-35 121.8 0.0 2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EIM88127.1 - 2.6e-05 24.3 0.0 4.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EIM88127.1 - 0.0022 18.3 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 EIM88127.1 - 0.0085 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 EIM88127.1 - 0.0097 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 WD40 PF00400.32 EIM88128.1 - 5.8e-09 36.4 0.5 0.026 15.4 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88128.1 - 0.00053 20.2 0.0 6 7.2 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIM88128.1 - 0.0015 18.4 2.8 0.98 9.4 0.0 2.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat IgGFc_binding PF17517.2 EIM88128.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 IgGFc binding protein Mg_trans_NIPA PF05653.14 EIM88129.1 - 1.2e-61 208.5 5.2 4.4e-58 196.7 6.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EIM88129.1 - 1.9e-05 24.8 0.6 1.9e-05 24.8 0.6 2.8 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 EIM88129.1 - 0.012 15.1 1.1 0.02 14.4 1.1 1.3 1 0 0 1 1 1 0 Solute carrier family 35 VMA21 PF09446.10 EIM88129.1 - 0.4 10.8 7.9 0.49 10.5 0.4 2.7 3 0 0 3 3 3 0 VMA21-like domain Pkinase PF00069.25 EIM88130.1 - 2.4e-71 240.2 0.0 8.6e-71 238.4 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88130.1 - 2.9e-31 108.7 0.0 1e-29 103.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM88130.1 - 4.9e-05 22.8 1.3 0.012 15.0 0.5 2.8 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EIM88130.1 - 0.00019 21.1 0.2 0.00038 20.1 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM88130.1 - 0.0034 17.3 0.4 0.12 12.3 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family EFTUD2 PF16004.5 EIM88130.1 - 0.017 15.7 2.9 0.017 15.7 2.9 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EPL1 PF10513.9 EIM88130.1 - 1.1 9.7 6.5 2.3 8.6 2.6 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Pkinase_fungal PF17667.1 EIM88130.1 - 1.2 7.8 8.9 13 4.4 8.9 2.1 1 1 0 1 1 1 0 Fungal protein kinase Methyltransf_8 PF05148.15 EIM88131.1 - 2.8e-61 207.1 0.0 4.5e-60 203.2 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EIM88131.1 - 8.7e-07 29.5 0.0 2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM88131.1 - 1.3e-05 25.9 0.0 2.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM88131.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM88131.1 - 0.0019 18.0 0.1 0.033 14.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM88131.1 - 0.031 15.0 0.0 0.11 13.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.14 EIM88131.1 - 1.1 7.5 5.3 1.5 7.0 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein UPRTase PF14681.6 EIM88133.1 - 9.7e-66 221.1 0.0 1.1e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EIM88133.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain FAD_binding_1 PF00667.20 EIM88134.1 - 1.7e-50 171.6 0.0 2.5e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EIM88134.1 - 1.9e-09 38.1 0.0 4.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 EIM88134.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.20 EIM88134.1 - 0.0078 16.1 0.0 0.047 13.6 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EIM88134.1 - 0.018 15.4 0.0 0.054 13.8 0.0 1.8 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 EIM88134.1 - 0.035 14.4 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.19 EIM88135.1 - 3.7e-106 356.0 13.7 4.4e-106 355.8 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GFO_IDH_MocA PF01408.22 EIM88136.1 - 3.8e-20 72.9 0.0 7.2e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EIM88136.1 - 4.4e-10 39.6 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EIM88136.1 - 0.024 15.3 0.0 0.041 14.5 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain RRM_1 PF00076.22 EIM88137.1 - 1.7e-18 66.2 0.1 1.2e-10 41.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM88137.1 - 0.11 12.1 0.0 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ubiquitin PF00240.23 EIM88138.1 - 3.5e-05 23.5 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EIM88138.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain cNMP_binding PF00027.29 EIM88139.1 - 2.5e-30 104.4 0.9 8.1e-14 51.5 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EIM88139.1 - 5e-09 35.7 0.1 1e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EphA2_TM PF14575.6 EIM88140.1 - 0.061 14.2 0.0 0.17 12.8 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 EIM88140.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Rifin Apt1 PF10351.9 EIM88140.1 - 0.12 11.2 12.9 0.18 10.6 12.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PARM PF17061.5 EIM88140.1 - 4.1 7.5 63.1 0.04 14.1 49.6 2.2 2 0 0 2 2 2 0 PARM SPX PF03105.19 EIM88140.1 - 6.1 6.6 24.4 0.087 12.7 15.0 2.0 2 0 0 2 2 2 0 SPX domain Glyoxal_oxid_N PF07250.11 EIM88141.1 - 1.6e-31 109.3 0.0 1.2e-30 106.5 0.0 2.2 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM88141.1 - 3e-18 65.9 0.7 6.4e-18 64.8 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 EIM88141.1 - 0.013 15.8 0.1 3.7 8.0 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 EIM88141.1 - 0.022 14.8 0.9 17 5.5 0.0 3.7 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 EIM88141.1 - 0.036 14.0 0.0 7.4 6.7 0.0 3.8 4 0 0 4 4 4 0 Kelch motif PMSR PF01625.21 EIM88142.1 - 1.4e-59 200.7 1.5 1.6e-59 200.5 1.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase ATP_bind_3 PF01171.20 EIM88143.1 - 6.4e-18 65.2 0.0 9.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EIM88143.1 - 1.3e-16 59.7 3.8 1.3e-16 59.7 3.8 3.9 5 0 0 5 5 5 1 Zinc-ribbon RecR PF02132.15 EIM88143.1 - 0.0039 16.7 1.2 0.0039 16.7 1.2 3.3 4 0 0 4 4 4 1 RecR protein HIPIP PF01355.17 EIM88143.1 - 0.031 14.6 6.3 5.4 7.4 1.2 3.4 3 0 0 3 3 3 0 High potential iron-sulfur protein tRNA_Me_trans PF03054.16 EIM88143.1 - 0.04 12.7 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase CTU2 PF10288.9 EIM88143.1 - 0.074 13.3 2.3 0.43 10.8 0.0 2.8 2 1 1 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 ThiI PF02568.14 EIM88143.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DNA_pol_B_palm PF14792.6 EIM88143.1 - 0.15 12.3 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm TF_Zn_Ribbon PF08271.12 EIM88143.1 - 2.1 8.0 12.5 0.86 9.2 0.4 3.6 3 1 1 4 4 3 0 TFIIB zinc-binding DUF2616 PF11077.8 EIM88143.1 - 8.1 6.1 8.6 1.3 8.7 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) PUF PF00806.19 EIM88144.1 - 7.4e-21 72.6 0.0 0.00037 20.0 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Bystin PF05291.11 EIM88145.1 - 3.6e-123 410.5 0.0 4.7e-123 410.1 0.0 1.1 1 0 0 1 1 1 1 Bystin HTH_32 PF13565.6 EIM88145.1 - 0.12 13.0 0.9 10 6.8 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain GDP_Man_Dehyd PF16363.5 EIM88146.1 - 2.4e-61 208.0 0.0 3.1e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EIM88146.1 - 2.4e-47 161.4 0.0 3.6e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM88146.1 - 2.9e-10 39.6 0.0 4.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM88146.1 - 3.1e-07 29.8 0.0 0.0029 16.8 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EIM88146.1 - 3.2e-06 26.5 0.0 4.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIM88146.1 - 2e-05 23.9 0.1 0.0028 16.8 0.1 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Abhydrolase_1 PF00561.20 EIM88147.1 - 2.5e-06 27.3 0.0 0.00012 21.9 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM88147.1 - 4.9e-06 27.3 1.5 8.8e-06 26.5 1.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lactococcin PF04369.13 EIM88147.1 - 0.19 11.9 0.2 0.46 10.7 0.0 1.7 2 0 0 2 2 2 0 Lactococcin-like family Abhydrolase_1 PF00561.20 EIM88148.1 - 1.3e-09 38.1 0.0 1e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM88148.1 - 0.00012 22.7 0.2 0.00024 21.8 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EIM88148.1 - 0.021 13.5 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.8 EIM88148.1 - 0.071 12.4 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EIM88148.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2458 PF10454.9 EIM88149.1 - 1.2e-07 31.6 5.9 2.3e-07 30.6 5.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 EIM88149.1 - 1.6e-05 24.6 3.8 3e-05 23.7 3.8 1.4 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein SAP130_C PF16014.5 EIM88149.1 - 0.0019 17.4 12.0 0.0025 17.0 12.0 1.3 1 0 0 1 1 1 1 Histone deacetylase complex subunit SAP130 C-terminus NAP PF00956.18 EIM88149.1 - 0.037 13.2 1.3 0.05 12.8 1.3 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF733 PF05306.11 EIM88149.1 - 0.26 11.6 4.6 0.22 11.8 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF733) Peptidase_M16 PF00675.20 EIM88149.1 - 0.32 11.0 5.7 0.7 9.9 3.3 2.4 2 1 0 2 2 2 0 Insulinase (Peptidase family M16) DUF2838 PF10998.8 EIM88150.1 - 1.3e-41 141.3 9.5 3e-41 140.1 9.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) DUF1640 PF07798.11 EIM88150.1 - 0.11 12.6 1.7 0.23 11.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF1656 PF07869.12 EIM88150.1 - 2 8.5 9.3 0.12 12.4 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Aft1_HRA PF11786.8 EIM88151.1 - 9.1e-22 77.2 11.6 9.1e-22 77.2 11.6 2.7 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 EIM88151.1 - 1.3e-07 31.6 2.0 2.7e-07 30.6 2.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EIM88151.1 - 0.00058 19.9 2.7 0.00058 19.9 2.7 1.8 2 0 0 2 2 2 1 Basic region leucine zipper PBP1_TM PF14812.6 EIM88151.1 - 0.11 12.9 0.3 0.11 12.9 0.3 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3445 PF11927.8 EIM88152.1 - 3.1e-66 223.2 0.0 3.9e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mt_ATP-synt_D PF05873.12 EIM88153.1 - 3.2e-14 53.1 3.5 3.9e-14 52.8 3.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) RPW8 PF05659.11 EIM88153.1 - 0.051 13.3 0.8 0.49 10.1 0.2 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CT_C_D PF02682.16 EIM88153.1 - 0.44 10.3 2.2 0.74 9.5 2.1 1.4 1 1 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Slu7 PF11708.8 EIM88153.1 - 0.85 9.3 4.1 4.5 7.0 0.4 2.0 1 1 1 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Adap_comp_sub PF00928.21 EIM88154.1 - 1.7e-52 178.4 0.0 2.1e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIM88154.1 - 4.1e-05 23.5 0.0 6.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Hexokinase_2 PF03727.16 EIM88155.1 - 4.7e-78 261.9 0.0 5.9e-45 153.6 0.0 2.1 1 1 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 EIM88155.1 - 1.5e-72 243.7 0.0 2.5e-72 243.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 EIM88155.1 - 0.00068 19.7 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) A_deamin PF02137.18 EIM88156.1 - 6.9e-60 203.2 0.0 8.9e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain ABC_tran PF00005.27 EIM88158.1 - 4.3e-16 59.7 0.1 3.2e-15 56.8 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIM88158.1 - 1e-10 41.9 6.8 5.1e-05 23.2 0.1 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM88158.1 - 0.00027 20.8 0.1 0.00038 20.3 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EIM88158.1 - 0.00032 20.4 0.1 0.00085 19.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EIM88158.1 - 0.00097 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EIM88158.1 - 0.0013 18.2 0.4 0.36 10.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EIM88158.1 - 0.0027 17.6 0.1 0.0042 17.0 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EIM88158.1 - 0.005 17.4 0.0 0.009 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EIM88158.1 - 0.009 15.7 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EIM88158.1 - 0.029 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIM88158.1 - 0.036 13.8 0.3 0.73 9.5 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EIM88158.1 - 0.047 13.8 0.4 0.081 13.0 0.4 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EIM88158.1 - 0.065 13.0 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 EIM88158.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EIM88158.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIM88158.1 - 0.16 11.9 0.4 0.35 10.8 0.4 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EIM88158.1 - 0.17 12.2 0.5 0.48 10.7 0.5 1.9 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.26 EIM88159.1 - 1.8e-15 56.8 0.0 3.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 EIM88159.1 - 0.00078 19.6 3.5 0.0018 18.4 3.5 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain UBA PF00627.31 EIM88159.1 - 0.0051 16.7 0.8 0.016 15.1 0.8 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-AN1 PF01428.16 EIM88159.1 - 0.078 13.2 3.3 0.17 12.1 3.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger MFS_1 PF07690.16 EIM88160.1 - 1.3e-36 126.2 23.5 1.3e-36 126.2 23.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Rtt106_N PF18215.1 EIM88160.1 - 0.0073 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain OATP PF03137.20 EIM88160.1 - 0.016 13.5 10.8 0.0036 15.7 4.5 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MS_channel PF00924.18 EIM88161.1 - 9.4e-18 64.5 0.5 1.5e-17 63.9 0.5 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EIM88161.1 - 0.00011 21.5 0.0 0.00025 20.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EIM88161.1 - 0.00029 20.2 0.1 0.00062 19.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EIM88161.1 - 0.00034 20.3 0.4 0.0014 18.4 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EIM88161.1 - 0.02 15.4 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 EIM88161.1 - 0.039 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Cas_TM1802 PF09484.10 EIM88161.1 - 0.095 11.4 0.1 0.34 9.6 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated protein TM1802 (cas_TM1802) PBP1_TM PF14812.6 EIM88161.1 - 0.77 10.2 6.1 10 6.6 0.1 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APG6_N PF17675.1 EIM88162.1 - 0.026 15.0 20.0 0.033 14.7 20.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region tRNA-synt_2 PF00152.20 EIM88163.1 - 3.9e-78 262.7 0.0 5.4e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIM88163.1 - 4.7e-11 42.5 0.0 2.3e-10 40.3 0.0 2.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EIM88163.1 - 9.3e-08 31.9 0.0 0.00072 19.1 0.0 2.9 4 0 0 4 4 4 2 tRNA synthetases class II core domain (F) Prefoldin PF02996.17 EIM88164.1 - 3.1e-25 88.4 5.5 8.5e-23 80.5 3.8 3.0 1 1 1 2 2 2 1 Prefoldin subunit SID-1_RNA_chan PF13965.6 EIM88164.1 - 0.02 13.3 0.1 0.025 13.0 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FlaC_arch PF05377.11 EIM88164.1 - 0.23 11.9 2.8 10 6.6 0.4 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RXT2_N PF08595.11 EIM88164.1 - 2.5 8.1 11.9 2.7 8.0 2.2 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Methyltransf_16 PF10294.9 EIM88167.1 - 4.7e-43 146.9 0.0 6.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EIM88167.1 - 0.00016 21.2 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EIM88167.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 EIM88167.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain BolA PF01722.18 EIM88169.1 - 1.1e-13 51.3 0.0 2.7e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein adh_short_C2 PF13561.6 EIM88170.1 - 1.8e-65 220.8 0.6 2.2e-65 220.5 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM88170.1 - 1.5e-47 161.6 0.5 1.8e-47 161.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM88170.1 - 3e-08 33.8 0.1 6.1e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EIM88170.1 - 0.0012 18.7 0.3 0.0057 16.6 0.3 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EIM88170.1 - 0.014 16.1 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EIM88170.1 - 0.055 13.1 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.6 EIM88170.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ntox4 PF15541.6 EIM88170.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial toxin 4 DUF962 PF06127.11 EIM88171.1 - 6.1e-24 83.9 4.0 3.7e-23 81.4 4.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Longin PF13774.6 EIM88172.1 - 6.9e-25 86.9 0.2 1.2e-24 86.1 0.0 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EIM88172.1 - 2.4e-14 52.9 0.0 4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Nab1 PF04902.12 EIM88172.1 - 0.064 13.7 0.7 0.094 13.1 0.1 1.5 2 0 0 2 2 2 0 Conserved region in Nab1 SLM4 PF16818.5 EIM88172.1 - 0.13 12.2 0.1 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein SLM4 DUF4646 PF15496.6 EIM88173.1 - 3e-06 27.9 1.3 0.0021 18.7 0.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) SR-25 PF10500.9 EIM88173.1 - 0.0003 20.5 15.5 0.00083 19.0 5.3 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EIM88173.1 - 2.9 6.1 19.3 0.52 8.5 6.4 2.0 2 0 0 2 2 2 0 CDC45-like protein IF-2B PF01008.17 EIM88174.1 - 2.5e-84 282.8 0.1 3.3e-84 282.5 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF3819 PF12842.7 EIM88174.1 - 0.024 14.6 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Forkhead PF00250.18 EIM88175.1 - 2e-25 88.9 0.1 3.3e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EIM88175.1 - 4.1e-07 30.3 0.0 6.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF3781 PF12636.7 EIM88175.1 - 0.13 12.2 1.0 0.55 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) MTP18 PF10558.9 EIM88176.1 - 3.5e-64 215.9 5.7 5.8e-63 211.9 5.7 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Nuf2 PF03800.14 EIM88177.1 - 6.3e-31 107.4 0.2 2.5e-30 105.4 0.2 2.1 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EIM88177.1 - 7.5e-29 100.2 25.0 7.5e-29 100.2 25.0 4.0 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain PRKG1_interact PF15898.5 EIM88177.1 - 0.3 12.0 42.1 2.7 9.0 9.1 4.0 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF3584 PF12128.8 EIM88177.1 - 0.8 7.1 43.8 0.38 8.2 40.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Prp19 PF08606.11 EIM88177.1 - 1.3 9.1 11.9 1.5 8.9 0.1 3.8 4 0 0 4 4 4 0 Prp19/Pso4-like GAS PF13851.6 EIM88177.1 - 2 7.7 43.3 0.5 9.7 24.7 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EIM88177.1 - 3 6.6 44.4 0.41 9.5 20.0 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 EIM88177.1 - 4.7 7.7 44.9 0.8 10.2 5.6 3.7 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF2373 PF10180.9 EIM88178.1 - 1.5e-15 56.7 0.7 3.6e-15 55.5 0.7 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Glyco_hydro_71 PF03659.14 EIM88179.1 - 5.5e-107 357.8 1.2 6.5e-107 357.6 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Aminotran_1_2 PF00155.21 EIM88180.1 - 5.8e-77 259.3 0.0 7.6e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIM88180.1 - 0.0006 18.4 0.0 0.0011 17.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EIM88180.1 - 0.001 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EIM88180.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pertussis_S1 PF02917.14 EIM88180.1 - 0.11 12.2 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 SR-25 PF10500.9 EIM88180.1 - 0.48 10.0 3.8 2.3 7.8 3.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Preseq_ALAS PF09029.10 EIM88180.1 - 4.1 7.9 12.5 3.5e+02 1.7 12.5 2.7 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence Aminotran_3 PF00202.21 EIM88181.1 - 6.4e-99 331.3 0.0 9e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 EIM88181.1 - 0.072 12.0 0.0 0.88 8.5 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V ATP-grasp_3 PF02655.14 EIM88182.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain NAD_binding_4 PF07993.12 EIM88183.1 - 1.5e-39 135.7 0.0 8.4e-39 133.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EIM88183.1 - 1.6e-23 83.0 0.0 1.5e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 EIM88183.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM88183.1 - 2.1e-05 24.8 0.0 6.5e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 EIM88183.1 - 0.00042 19.5 0.0 0.55 9.3 0.0 2.4 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.10 EIM88183.1 - 0.00061 19.7 0.2 0.0015 18.5 0.2 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM88183.1 - 0.0016 17.6 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EIM88183.1 - 0.0035 16.4 0.0 0.012 14.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM88183.1 - 0.015 14.7 0.1 0.049 13.0 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EIM88183.1 - 0.2 11.2 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Methyltransf_3 PF01596.17 EIM88184.1 - 2.5e-36 124.8 0.0 3.2e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EIM88184.1 - 9.3e-07 29.8 0.0 2.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EIM88184.1 - 0.0032 17.1 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Spermine_synth PF01564.17 EIM88184.1 - 0.025 14.0 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain DHQ_synthase PF01761.20 EIM88185.1 - 3.5e-51 173.9 0.0 4.7e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EIM88185.1 - 1.5e-12 47.8 0.0 2.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cpn60_TCP1 PF00118.24 EIM88185.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family cwf21 PF08312.12 EIM88186.1 - 1.2e-12 47.7 11.5 1.2e-12 47.7 11.5 2.8 3 1 0 3 3 3 1 cwf21 domain Flavokinase PF01687.17 EIM88187.1 - 3.9e-32 110.8 0.0 5.3e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase TAF8_C PF10406.9 EIM88188.1 - 5.6e-10 39.6 6.8 5.7e-10 39.6 4.8 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EIM88188.1 - 9.8e-10 38.3 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated DUF3622 PF12286.8 EIM88188.1 - 0.047 14.0 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) Myb_DNA-binding PF00249.31 EIM88189.1 - 2.1e-45 152.7 5.9 3.2e-15 56.0 0.1 5.5 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIM88189.1 - 7.4e-36 122.2 0.7 8.2e-15 54.8 0.1 5.4 3 1 2 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EIM88189.1 - 1.3e-05 25.5 1.6 5.7 7.4 0.0 4.6 4 0 0 4 4 4 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EIM88189.1 - 0.02 14.9 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 SLIDE DUF1115 PF06544.12 EIM88190.1 - 2.9e-15 56.6 0.0 6.9e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 EIM88190.1 - 0.04 14.2 0.1 0.07 13.4 0.1 1.5 1 0 0 1 1 1 0 RWD domain Asp PF00026.23 EIM88191.1 - 2.4e-75 253.9 1.4 3.3e-75 253.4 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM88191.1 - 1.5e-07 31.8 0.5 0.0036 17.6 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EIM88191.1 - 0.0014 18.4 0.1 0.0046 16.7 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Ribosomal_L13 PF00572.18 EIM88193.1 - 2.1e-51 173.4 0.1 2.4e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 adh_short PF00106.25 EIM88195.1 - 1.4e-08 34.4 0.0 3.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM88195.1 - 1.5e-06 27.9 0.0 6.8e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MT-A70 PF05063.14 EIM88196.1 - 6.7e-57 192.1 0.0 8.9e-57 191.7 0.0 1.2 1 0 0 1 1 1 1 MT-A70 DUF1770 PF08589.10 EIM88197.1 - 0.034 15.1 3.4 0.12 13.3 3.4 2.0 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Abhydrolase_1 PF00561.20 EIM88198.1 - 1.4e-21 77.3 0.0 4.3e-21 75.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM88198.1 - 3.7e-18 65.7 0.0 3.5e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM88198.1 - 3.5e-14 54.0 1.1 3.5e-14 54.0 1.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 EIM88198.1 - 6.5e-06 26.0 0.3 1.6e-05 24.7 0.3 1.9 1 1 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 EIM88198.1 - 0.00011 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EIM88198.1 - 0.00023 21.1 0.0 0.036 13.9 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 EIM88198.1 - 0.00095 17.9 0.0 0.0024 16.6 0.0 1.6 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.13 EIM88198.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 EIM88198.1 - 0.0086 16.0 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 EIM88198.1 - 0.023 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EIM88198.1 - 0.034 13.5 0.0 0.081 12.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3530 PF12048.8 EIM88198.1 - 0.099 12.0 0.1 0.29 10.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.16 EIM88198.1 - 0.1 12.4 0.0 0.4 10.4 0.0 1.9 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 EIM88198.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ribosomal_S11 PF00411.19 EIM88199.1 - 4.5e-10 39.9 0.0 7.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Herpes_pp85 PF04637.12 EIM88199.1 - 1.4 7.3 2.9 2 6.7 2.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) UCR_UQCRX_QCR9 PF05365.12 EIM88200.1 - 5.1e-18 64.7 5.1 5.9e-18 64.5 5.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like IPK PF03770.16 EIM88201.1 - 1.2e-49 168.9 0.0 2.3e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S7e PF01251.18 EIM88201.1 - 0.14 11.9 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S7e Arf PF00025.21 EIM88204.1 - 6.7e-72 240.6 0.0 7.9e-72 240.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIM88204.1 - 5.9e-15 55.2 0.0 8.1e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EIM88204.1 - 4.5e-14 52.4 0.1 3.2e-09 36.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EIM88204.1 - 5.3e-14 52.5 0.0 7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIM88204.1 - 1.4e-10 41.0 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EIM88204.1 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIM88204.1 - 0.0003 20.8 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 EIM88204.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) WD40 PF00400.32 EIM88205.1 - 2.4e-20 72.5 12.5 6e-07 30.1 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88205.1 - 0.0015 18.8 0.1 0.095 13.0 0.0 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM88205.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Iso_dh PF00180.20 EIM88206.1 - 3e-101 339.0 0.0 3.4e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_125 PF06824.11 EIM88208.1 - 4e-153 510.2 0.5 4.7e-153 510.0 0.5 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) C2 PF00168.30 EIM88209.1 - 3.8e-11 43.2 0.0 3.3e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain Peptidase_M28 PF04389.17 EIM88211.1 - 4.3e-27 95.1 0.0 6.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIM88211.1 - 4.6e-07 29.8 0.0 1.7e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L11 PF00298.19 EIM88212.1 - 2.2e-28 98.5 0.1 3.7e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EIM88212.1 - 9.9e-26 89.4 0.4 1.8e-25 88.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Glyco_hydro_cc PF11790.8 EIM88215.1 - 3.9e-59 200.1 9.4 6.1e-59 199.5 9.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.22 EIM88216.1 - 4.3e-28 96.9 0.0 2e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM88216.1 - 0.00026 20.6 0.0 0.92 9.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EIM88216.1 - 0.0015 18.5 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain Limkain-b1 PF11608.8 EIM88216.1 - 0.012 15.6 1.1 2 8.6 0.1 3.0 2 1 0 2 2 2 0 Limkain b1 OB_RNB PF08206.11 EIM88216.1 - 0.32 10.7 2.5 13 5.5 0.1 3.2 2 1 0 2 2 2 0 Ribonuclease B OB domain TAF4 PF05236.14 EIM88216.1 - 4.9 6.8 15.8 3.1 7.5 14.3 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4187 PF13821.6 EIM88217.1 - 2.2e-22 78.6 1.4 4.9e-22 77.5 1.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EIM88217.1 - 9.2e-07 28.7 0.4 9.2e-07 28.7 0.4 1.9 2 0 0 2 2 2 1 G-patch domain DNA_RNApol_7kD PF03604.13 EIM88219.1 - 1.9e-17 62.6 7.6 2.4e-17 62.3 7.6 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 EIM88219.1 - 0.0034 17.4 0.5 0.0048 16.9 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_10 PF10058.9 EIM88219.1 - 0.0052 16.5 0.6 0.32 10.8 0.1 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 EIM88219.1 - 0.0061 16.6 0.3 0.0064 16.5 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EIM88219.1 - 0.0066 16.5 2.8 0.014 15.5 2.8 1.5 1 1 0 1 1 1 1 Zinc ribbon domain zf-C3HC PF07967.13 EIM88219.1 - 0.01 15.9 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like zf-ISL3 PF14690.6 EIM88219.1 - 0.011 16.4 1.9 0.055 14.1 0.3 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 MCM_OB PF17207.3 EIM88219.1 - 0.015 15.2 0.5 0.015 15.1 0.5 1.1 1 0 0 1 1 1 0 MCM OB domain Zn_ribbon_recom PF13408.6 EIM88219.1 - 0.016 15.7 3.1 0.27 11.8 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc-ribbon_6 PF10005.9 EIM88219.1 - 0.02 15.6 0.3 0.034 14.8 0.3 1.4 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EIM88219.1 - 0.026 14.2 1.0 0.026 14.2 1.0 2.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.6 EIM88219.1 - 0.033 14.1 5.6 0.66 9.9 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain NinF PF05810.12 EIM88219.1 - 0.034 14.0 0.2 0.044 13.7 0.2 1.2 1 0 0 1 1 1 0 NinF protein OrfB_Zn_ribbon PF07282.11 EIM88219.1 - 0.06 13.3 2.4 0.088 12.8 2.0 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 EIM88219.1 - 0.076 12.5 2.7 1.1 8.9 0.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 EIM88219.1 - 0.13 11.9 2.1 5.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-NADH-PPase PF09297.11 EIM88219.1 - 0.19 11.4 3.4 0.59 9.8 3.4 1.8 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 EIM88219.1 - 0.2 11.1 2.2 2 8.0 2.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 EIM88219.1 - 0.39 10.5 3.9 6.2 6.6 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF3425 PF11905.8 EIM88221.1 - 7.4e-14 51.8 0.1 5.7e-13 48.9 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EIM88221.1 - 3.7e-08 33.3 2.4 3.7e-08 33.3 2.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EIM88221.1 - 0.0018 18.3 7.3 0.0039 17.2 3.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper COA2 PF17051.5 EIM88222.1 - 0.00019 21.4 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 COX14 PF14880.6 EIM88222.1 - 0.083 12.7 0.5 0.21 11.4 0.1 1.9 2 1 0 2 2 2 0 Cytochrome oxidase c assembly MFS_1 PF07690.16 EIM88223.1 - 1.8e-32 112.7 46.4 3.4e-28 98.6 27.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM88223.1 - 0.00018 20.5 7.1 0.00018 20.5 7.1 4.5 4 1 1 5 5 5 3 Sugar (and other) transporter TRI12 PF06609.13 EIM88223.1 - 0.0011 17.5 10.2 0.0011 17.5 10.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 EIM88225.1 - 1.5e-70 237.6 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88225.1 - 2.2e-29 102.6 0.0 7.2e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIM88225.1 - 2.9e-10 39.9 0.2 2.6e-05 23.7 0.0 3.0 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EIM88225.1 - 0.0004 19.3 0.0 0.00086 18.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM88225.1 - 0.16 11.9 0.0 0.49 10.3 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EIM88225.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.17 EIM88226.1 - 1.8e-18 67.0 0.0 2.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EIM88226.1 - 0.17 12.4 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Ets-domain SNARE_assoc PF09335.11 EIM88227.1 - 6.3e-14 52.5 7.2 7.1e-14 52.3 6.0 1.7 1 1 1 2 2 2 1 SNARE associated Golgi protein Mito_fiss_reg PF05308.11 EIM88228.1 - 0.24 11.5 1.2 0.33 11.0 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator PEX11 PF05648.14 EIM88229.1 - 8.6e-14 51.5 3.2 8.1e-08 32.0 0.3 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Mhr1 PF12829.7 EIM88229.1 - 0.11 12.6 0.3 20 5.4 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination Tctex-1 PF03645.13 EIM88230.1 - 3.8e-13 49.6 0.0 4.4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DOT1 PF08123.13 EIM88231.1 - 0.074 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TPMT PF05724.11 EIM88232.1 - 1.4e-25 90.2 0.0 1.8e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EIM88232.1 - 4e-08 33.9 0.0 6.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM88232.1 - 7.1e-05 22.6 0.0 9.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EIM88233.1 - 1.6e-32 112.9 0.0 2e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EIM88233.1 - 6.9e-11 42.7 0.0 1e-10 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM88233.1 - 1e-08 35.7 0.0 1.5e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM88233.1 - 3.7e-08 33.3 0.0 4.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM88233.1 - 7.6e-08 33.0 0.0 1.1e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM88233.1 - 1.7e-06 28.0 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain OmdA PF13376.6 EIM88233.1 - 0.061 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated AlaDh_PNT_C PF01262.21 EIM88233.1 - 0.25 10.6 0.0 0.36 10.1 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PPR_2 PF13041.6 EIM88234.1 - 1.4e-06 28.3 0.0 0.00047 20.3 0.0 3.1 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EIM88234.1 - 3.1e-06 27.2 0.0 0.0048 16.9 0.0 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain Methyltransf_23 PF13489.6 EIM88235.1 - 6.2e-18 65.2 0.0 1.2e-17 64.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM88235.1 - 9.4e-16 58.3 0.1 3.8e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM88235.1 - 6.4e-15 55.3 0.4 1e-14 54.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM88235.1 - 3.7e-14 53.1 0.0 1.1e-13 51.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM88235.1 - 1.8e-12 47.9 0.1 7.7e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM88235.1 - 1.6e-07 30.9 0.0 2.3e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EIM88235.1 - 2.3e-06 27.3 0.0 4.9e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EIM88235.1 - 3.1e-05 23.5 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 EIM88235.1 - 0.00078 19.1 0.0 0.0013 18.3 0.0 1.3 1 1 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 EIM88235.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EIM88235.1 - 0.0058 16.6 0.0 0.011 15.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain DUF2312 PF10073.9 EIM88235.1 - 0.027 14.1 0.7 0.68 9.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) PCMT PF01135.19 EIM88235.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) S_tail_recep_bd PF14928.6 EIM88235.1 - 0.092 13.4 0.2 0.12 13.0 0.2 1.3 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain DREV PF05219.12 EIM88235.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase NUMOD3 PF07460.11 EIM88235.1 - 0.11 12.7 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) AAA PF00004.29 EIM88236.1 - 4.4e-29 101.6 0.0 7.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM88236.1 - 2.1e-07 31.5 0.5 5.4e-07 30.1 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EIM88236.1 - 4.3e-07 30.3 0.3 6e-06 26.6 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 EIM88236.1 - 1.8e-06 28.5 0.0 3.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EIM88236.1 - 4.2e-05 23.6 0.0 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EIM88236.1 - 0.00022 21.4 0.0 0.00066 19.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM88236.1 - 0.00034 20.5 0.1 0.001 18.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EIM88236.1 - 0.0012 18.1 0.0 0.059 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EIM88236.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EIM88236.1 - 0.002 18.4 0.0 0.0062 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EIM88236.1 - 0.0021 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 EIM88236.1 - 0.0031 17.3 0.1 0.0075 16.0 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase NACHT PF05729.12 EIM88236.1 - 0.0032 17.4 0.1 0.0075 16.2 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 EIM88236.1 - 0.0032 17.5 0.1 0.0077 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EIM88236.1 - 0.0036 17.7 0.0 0.0093 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 EIM88236.1 - 0.0039 16.9 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIM88236.1 - 0.004 16.9 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EIM88236.1 - 0.0041 16.7 0.2 0.36 10.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM88236.1 - 0.0046 16.7 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EIM88236.1 - 0.0058 15.9 0.0 0.0081 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EIM88236.1 - 0.006 16.3 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EIM88236.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EIM88236.1 - 0.0062 16.5 0.0 1.2 9.1 0.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EIM88236.1 - 0.03 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EIM88236.1 - 0.043 14.2 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EIM88236.1 - 0.046 13.6 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EIM88236.1 - 0.057 13.5 0.0 0.78 9.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EIM88236.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 EIM88236.1 - 0.068 13.6 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EIM88236.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EIM88236.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 EIM88236.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EIM88236.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 EIM88236.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 EIM88236.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rdx PF10262.9 EIM88237.1 - 6e-26 90.4 0.0 7e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Rdx family CLASP_N PF12348.8 EIM88238.1 - 1.1e-69 234.4 1.9 2.1e-61 207.4 0.4 4.2 3 1 1 4 4 4 3 CLASP N terminal HEAT PF02985.22 EIM88238.1 - 3.2e-05 23.8 0.2 18 5.9 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EIM88238.1 - 0.00026 21.1 0.1 0.85 9.6 0.0 3.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TPR_20 PF14561.6 EIM88238.1 - 0.2 12.0 1.6 14 6.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 EIM88238.1 - 0.25 11.9 1.8 32 5.2 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat Rhomboid PF01694.22 EIM88239.1 - 2.7e-26 92.4 9.9 4.3e-26 91.7 9.9 1.3 1 0 0 1 1 1 1 Rhomboid family Sedlin_N PF04628.13 EIM88240.1 - 3.6e-36 124.2 0.1 1.7e-35 122.0 0.1 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EIM88240.1 - 3.8e-09 36.6 0.1 6.5e-09 35.9 0.0 1.4 2 0 0 2 2 2 1 Sybindin-like family TFIIA PF03153.13 EIM88241.1 - 0.033 14.2 34.6 0.038 14.0 34.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ThiG PF05690.14 EIM88241.1 - 0.033 13.5 3.4 0.07 12.4 0.3 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Dynactin_p62 PF05502.13 EIM88241.1 - 1.1 7.9 12.2 1.4 7.6 12.2 1.1 1 0 0 1 1 1 0 Dynactin p62 family Hydin_ADK PF17213.3 EIM88241.1 - 2.3 8.5 10.5 3.1 8.0 10.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 EIM88241.1 - 6.7 6.7 9.2 8 6.4 9.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 EIM88241.1 - 7 3.6 16.7 8.1 3.4 16.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 EIM88241.1 - 9.1 4.4 28.2 11 4.2 28.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Actin PF00022.19 EIM88243.1 - 3.1e-115 385.1 0.0 3.5e-115 384.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EIM88243.1 - 6e-07 28.6 0.0 0.00064 18.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BOP1NT PF08145.12 EIM88244.1 - 2e-103 345.9 6.7 2.7e-103 345.4 6.7 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EIM88244.1 - 7.8e-19 67.7 3.7 0.0056 17.5 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88244.1 - 3.7e-05 24.0 0.0 0.76 10.1 0.0 4.2 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EIM88244.1 - 0.31 9.3 0.0 0.52 8.6 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2423 PF10338.9 EIM88246.1 - 2.2e-15 56.6 5.5 2.2e-15 56.6 5.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 EIM88246.1 - 0.0095 16.5 4.1 0.014 16.0 4.1 1.5 1 1 0 1 1 1 1 Learning-associated protein CDC45 PF02724.14 EIM88246.1 - 2.7 6.2 6.1 2.8 6.1 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_16 PF00722.21 EIM88247.1 - 3.4e-15 55.9 0.4 6e-15 55.2 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nop10p PF04135.12 EIM88247.1 - 0.0023 17.9 0.1 0.62 10.2 0.0 3.2 3 0 0 3 3 3 2 Nucleolar RNA-binding protein, Nop10p family RRM_1 PF00076.22 EIM88248.1 - 1.9e-16 59.6 0.0 3.9e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.20 EIM88248.1 - 3.6e-11 43.0 0.0 1.3e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L19 IMD PF08397.11 EIM88249.1 - 0.00016 21.1 0.8 0.00025 20.5 0.8 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain ARD PF03079.14 EIM88249.1 - 0.0008 19.6 1.1 0.0012 19.0 1.1 1.2 1 0 0 1 1 1 1 ARD/ARD' family Glyco_hydro_66 PF13199.6 EIM88249.1 - 0.00098 17.9 0.3 0.0013 17.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 Phage_int_SAM_2 PF12834.7 EIM88249.1 - 0.091 13.5 0.3 0.2 12.4 0.3 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal Period_C PF12114.8 EIM88249.1 - 1.8 8.1 4.5 3.1 7.3 4.5 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CorA PF01544.18 EIM88249.1 - 2.6 7.3 4.6 4 6.7 4.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein tRNA-synt_2 PF00152.20 EIM88250.1 - 6.7e-87 291.5 0.0 6.3e-86 288.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIM88250.1 - 4.3e-07 29.8 0.0 1.3e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain F-box PF00646.33 EIM88251.1 - 0.00068 19.5 0.5 0.0019 18.0 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EIM88251.1 - 0.0037 17.1 0.8 0.0087 15.9 0.8 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EIM88251.1 - 0.0043 16.9 1.4 0.011 15.7 1.4 1.7 1 0 0 1 1 1 1 F-box-like ACPS PF01648.20 EIM88252.1 - 3.3e-13 49.8 0.0 2.2e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily ICAT PF06384.11 EIM88252.1 - 0.23 11.7 0.0 0.39 11.0 0.0 1.3 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT PfkB PF00294.24 EIM88253.1 - 1.7e-15 57.1 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EIM88253.1 - 0.0023 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase LSM PF01423.22 EIM88254.1 - 1e-21 76.4 0.0 1.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIM88254.1 - 0.0066 16.6 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Fungal_trans PF04082.18 EIM88255.1 - 9.3e-32 110.1 0.0 1.3e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM88255.1 - 2.8e-09 36.9 11.6 5.1e-09 36.1 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_assoc PF16606.5 EIM88255.1 - 0.066 13.4 3.0 0.28 11.4 3.0 2.1 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers Acyl-CoA_dh_1 PF00441.24 EIM88256.1 - 1.2e-30 106.7 0.5 1.9e-30 106.1 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIM88256.1 - 1.3e-18 67.0 0.0 3.8e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIM88256.1 - 1.7e-12 47.8 0.6 3.5e-12 46.7 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EIM88256.1 - 1e-10 42.2 0.0 3e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 EIM88256.1 - 0.067 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal SIR2 PF02146.17 EIM88257.1 - 1.8e-33 115.9 0.0 8e-18 65.0 0.0 2.4 1 1 0 2 2 2 2 Sir2 family PNTB PF02233.16 EIM88257.1 - 0.0013 17.8 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 EIM88257.1 - 0.02 14.6 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Transketolase_C PF02780.20 EIM88257.1 - 0.12 12.3 0.0 0.7 9.8 0.0 2.0 2 0 0 2 2 2 0 Transketolase, C-terminal domain Complex1_LYR_2 PF13233.6 EIM88258.1 - 7.9e-12 45.8 0.0 9.4e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Complex1_LYR-like WD40 PF00400.32 EIM88259.1 - 2.2e-33 113.7 24.0 2.4e-05 25.0 0.8 9.5 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88259.1 - 3.3e-13 49.7 0.4 0.026 14.8 0.1 8.0 5 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 EIM88259.1 - 0.00018 21.3 0.9 0.0021 17.8 0.4 2.5 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 EIM88259.1 - 0.0034 16.4 0.0 1.1 8.2 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EIM88259.1 - 0.14 12.0 0.1 34 4.3 0.0 2.9 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Pet191_N PF10203.9 EIM88260.1 - 1.1e-26 92.9 6.2 1.4e-26 92.6 6.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NGP1NT PF08153.12 EIM88260.1 - 0.068 13.3 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 NGP1NT (NUC091) domain Cmc1 PF08583.10 EIM88260.1 - 0.15 12.1 5.1 5 7.2 0.2 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCV_T PF01571.21 EIM88261.1 - 0.00012 21.6 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain ACPS PF01648.20 EIM88262.1 - 2.3e-09 37.4 0.1 6.4e-08 32.7 0.1 2.2 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NAD_Gly3P_dh_C PF07479.14 EIM88263.1 - 3.9e-47 160.1 0.1 6.1e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EIM88263.1 - 4.4e-33 114.5 0.0 6.6e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EIM88263.1 - 2.2e-06 27.4 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EIM88263.1 - 0.0018 18.8 0.0 0.011 16.3 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EIM88263.1 - 0.0051 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EIM88263.1 - 0.011 16.0 0.0 0.065 13.5 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EIM88263.1 - 0.025 14.6 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EIM88263.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VARLMGL PF14383.6 EIM88263.1 - 0.13 11.8 1.1 0.3 10.7 1.1 1.6 1 0 0 1 1 1 0 DUF761-associated sequence motif Hydrolase_3 PF08282.12 EIM88264.1 - 1.5e-41 142.9 0.0 1.9e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EIM88264.1 - 1.2e-10 41.4 0.0 1.2e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EIM88264.1 - 3.7e-05 24.1 0.1 0.26 11.5 0.0 3.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 EIM88264.1 - 0.013 16.0 0.0 1.7 9.0 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EIM88264.1 - 0.027 14.6 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AKAP95 PF04988.12 EIM88264.1 - 0.058 13.6 0.1 0.37 11.0 0.0 2.0 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) HAD_2 PF13419.6 EIM88264.1 - 0.15 12.1 0.4 2.7 8.0 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF1640 PF07798.11 EIM88265.1 - 1.2e-38 133.0 9.8 1.3e-38 132.7 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 EIM88265.1 - 0.016 14.6 0.8 0.022 14.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EIM88265.1 - 0.13 12.3 3.5 0.26 11.4 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PsbP PF01789.16 EIM88265.1 - 0.16 12.1 0.6 0.24 11.5 0.6 1.3 1 0 0 1 1 1 0 PsbP DUF4404 PF14357.6 EIM88265.1 - 0.58 10.8 4.7 1.3 9.8 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) NUDE_C PF04880.13 EIM88265.1 - 6.6 7.2 18.3 3.6 8.0 5.9 2.4 1 1 0 2 2 2 0 NUDE protein, C-terminal conserved region ATP_bind_1 PF03029.17 EIM88266.1 - 1.1e-77 261.1 0.0 1.4e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArsA_ATPase PF02374.15 EIM88266.1 - 0.00036 19.8 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_16 PF13191.6 EIM88266.1 - 0.0015 18.9 0.0 0.0045 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EIM88266.1 - 0.0046 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF463 PF04317.12 EIM88266.1 - 0.007 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 YcjX-like family, DUF463 NTPase_1 PF03266.15 EIM88266.1 - 0.0074 16.2 0.1 0.029 14.3 0.1 2.0 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 EIM88266.1 - 0.0082 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIM88266.1 - 0.0093 16.5 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EIM88266.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 EIM88266.1 - 0.011 15.7 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CLP1_P PF16575.5 EIM88266.1 - 0.014 15.2 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 EIM88266.1 - 0.021 14.5 0.1 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EIM88266.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EIM88266.1 - 0.023 15.0 0.0 0.042 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIM88266.1 - 0.029 13.9 0.1 0.063 12.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EIM88266.1 - 0.029 14.1 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 EIM88266.1 - 0.041 13.3 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MeaB PF03308.16 EIM88266.1 - 0.047 12.7 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EIM88266.1 - 0.057 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EIM88266.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_31 PF13614.6 EIM88266.1 - 0.064 13.2 0.0 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EIM88266.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EIM88266.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 EIM88266.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.6 EIM88266.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIM88266.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EIM88266.1 - 0.21 11.3 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EIM88266.1 - 0.21 11.2 0.0 0.52 9.9 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 EIM88266.1 - 0.22 11.2 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 EIM88266.1 - 0.25 10.8 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SOG2 PF10428.9 EIM88268.1 - 0.86 8.7 12.8 0.92 8.6 12.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Dynamin_N PF00350.23 EIM88269.1 - 3.5e-17 63.0 8.6 4.4e-17 62.7 0.0 4.1 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EIM88269.1 - 5.2e-06 26.5 1.0 0.0019 18.2 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EIM88269.1 - 0.0038 16.6 0.6 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EIM88269.1 - 0.0048 16.8 1.4 0.014 15.3 0.1 2.4 3 0 0 3 3 2 1 RsgA GTPase ABC_tran PF00005.27 EIM88269.1 - 0.0076 16.8 0.0 0.0076 16.8 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 EIM88269.1 - 0.018 15.4 0.7 0.47 10.8 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EIM88269.1 - 0.028 14.7 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Syntaxin_2 PF14523.6 EIM88269.1 - 0.038 14.4 14.4 15 6.1 3.1 5.4 5 0 0 5 5 5 0 Syntaxin-like protein AAA_23 PF13476.6 EIM88269.1 - 0.048 14.2 0.2 0.048 14.2 0.2 4.3 2 1 1 3 3 1 0 AAA domain Sec8_exocyst PF04048.14 EIM88269.1 - 0.15 11.9 16.4 0.59 10.0 0.5 4.9 6 0 0 6 6 6 0 Sec8 exocyst complex component specific domain AAA_29 PF13555.6 EIM88269.1 - 0.18 11.6 0.2 0.37 10.6 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain APG17 PF04108.12 EIM88269.1 - 0.49 9.4 20.0 0.081 12.0 3.2 3.7 4 0 0 4 4 4 0 Autophagy protein Apg17 XhlA PF10779.9 EIM88269.1 - 0.51 10.6 13.2 0.12 12.6 2.8 3.1 2 0 0 2 2 2 0 Haemolysin XhlA FAA_hydrolase_N PF09298.11 EIM88269.1 - 0.57 10.4 3.9 6 7.1 0.7 3.5 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal AAA_21 PF13304.6 EIM88269.1 - 4.3 7.1 5.7 8.7 6.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1664 PF07889.12 EIM88269.1 - 7 6.7 16.1 0.064 13.3 1.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Pheromone PF08015.11 EIM88269.1 - 8.6 7.5 7.2 43 5.2 7.2 2.3 1 0 0 1 1 1 0 Fungal mating-type pheromone MFS_1 PF07690.16 EIM88271.1 - 9.6e-37 126.7 19.7 9.6e-37 126.7 19.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1180 PF06679.12 EIM88271.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DC_STAMP PF07782.13 EIM88271.1 - 0.072 12.9 0.6 0.19 11.6 0.6 1.7 1 0 0 1 1 1 0 DC-STAMP-like protein Thiolase_N PF00108.23 EIM88272.1 - 6.8e-88 294.4 2.4 9.2e-88 294.0 2.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIM88272.1 - 1.7e-38 131.0 4.5 1.8e-38 131.0 0.6 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EIM88272.1 - 5.6e-05 22.8 2.3 0.00022 20.9 2.2 1.9 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EIM88272.1 - 0.17 11.8 5.6 0.32 10.9 0.4 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Autophagy_act_C PF03987.15 EIM88273.1 - 5.4e-18 65.3 0.3 9.5e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.18 EIM88274.1 - 3.2e-92 307.7 1.5 4e-92 307.4 1.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EIM88274.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Glyco_hydro_47 PF01532.20 EIM88275.1 - 5.8e-115 384.8 0.0 8.6e-115 384.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 EIM88275.1 - 0.00017 21.6 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.12 EIM88276.1 - 1.4e-28 98.7 5.0 2.2e-15 56.5 0.7 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DpnI PF06044.12 EIM88276.1 - 0.14 11.8 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Dam-replacing family DUF2256 PF10013.9 EIM88276.1 - 0.21 11.7 1.5 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_2 PF13639.6 EIM88278.1 - 1.1e-06 28.9 9.4 1.9e-06 28.1 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM88278.1 - 1.5e-05 24.7 9.9 2.9e-05 23.9 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM88278.1 - 3.5e-05 23.8 8.0 6.7e-05 22.8 8.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIM88278.1 - 0.00019 21.3 10.9 0.00035 20.5 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM88278.1 - 0.0022 17.8 11.3 0.0032 17.3 10.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EIM88278.1 - 0.0037 17.1 10.5 0.0077 16.1 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM88278.1 - 0.0043 16.8 8.1 0.0043 16.8 8.1 1.8 1 1 1 2 2 2 1 RING-like zinc finger GIT_CC PF16559.5 EIM88278.1 - 0.005 16.7 1.1 2.6 8.0 0.0 3.4 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 EIM88278.1 - 0.0069 16.8 14.3 0.2 12.1 0.1 2.9 2 1 1 3 3 2 2 Cell division protein ZapB TSC22 PF01166.18 EIM88278.1 - 0.0091 16.3 1.3 2.8 8.3 0.1 2.6 2 0 0 2 2 2 1 TSC-22/dip/bun family zf-C3HC4_4 PF15227.6 EIM88278.1 - 0.027 14.6 12.6 0.051 13.8 12.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF5595 PF18077.1 EIM88278.1 - 0.072 13.2 2.4 4.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) HALZ PF02183.18 EIM88278.1 - 0.094 13.0 6.3 1.7 8.9 0.4 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 EIM88278.1 - 0.097 12.5 7.7 2.9 7.7 1.7 2.9 3 0 0 3 3 2 0 Septum formation initiator DUF4407 PF14362.6 EIM88278.1 - 0.28 10.5 5.1 0.71 9.2 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LapA_dom PF06305.11 EIM88278.1 - 0.32 10.8 6.3 1.9 8.3 0.4 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain FUSC PF04632.12 EIM88278.1 - 0.72 8.3 2.1 1.1 7.7 2.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-RING_4 PF14570.6 EIM88278.1 - 0.96 9.3 11.4 2 8.3 11.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain betaPIX_CC PF16523.5 EIM88278.1 - 1.3 8.9 9.1 1.7 8.5 3.0 3.3 1 1 1 3 3 3 0 betaPIX coiled coil zf-RING_6 PF14835.6 EIM88278.1 - 1.6 8.7 6.3 2.8 7.9 6.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein V_ATPase_I PF01496.19 EIM88278.1 - 2.1 6.1 4.3 3.3 5.5 4.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 EIM88278.1 - 2.5 8.1 7.5 0.54 10.3 1.9 2.6 2 1 0 2 2 2 0 FlxA-like protein YabA PF06156.13 EIM88278.1 - 2.5 8.8 12.3 1.1 9.9 0.1 3.0 1 1 1 2 2 2 0 Initiation control protein YabA RhoGEF PF00621.20 EIM88279.1 - 9.3e-33 114.0 0.0 1.7e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Cnn_1N PF07989.11 EIM88279.1 - 0.17 12.1 2.8 0.13 12.5 0.3 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 BMFP PF04380.13 EIM88279.1 - 3.9 8.0 12.5 3.9 8.0 6.4 3.1 2 1 1 3 3 3 0 Membrane fusogenic activity GFO_IDH_MocA PF01408.22 EIM88280.1 - 4.1e-16 59.9 0.0 7.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIM88280.1 - 0.043 14.5 0.1 0.098 13.3 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Lactamase_B_2 PF12706.7 EIM88283.1 - 6e-12 45.5 0.1 2.5e-07 30.4 0.1 3.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EIM88283.1 - 4.4e-07 29.5 0.0 7.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EIM88283.1 - 2.4e-06 27.7 0.2 5.5e-06 26.5 0.1 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 EIM88283.1 - 0.06 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II THOC7 PF05615.13 EIM88284.1 - 1.7e-30 106.0 2.5 1.7e-30 106.0 2.5 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 CCDC-167 PF15188.6 EIM88284.1 - 0.045 14.1 4.9 0.55 10.6 1.3 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 FAM101 PF15068.6 EIM88284.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 FAM101 family zf-C4H2 PF10146.9 EIM88284.1 - 3.9 7.7 7.3 3.2 8.0 5.5 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein DUF202 PF02656.15 EIM88285.1 - 7.6e-15 55.1 2.2 9.8e-15 54.8 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Methyltransf_3 PF01596.17 EIM88286.1 - 2e-39 135.0 0.0 2.6e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EIM88286.1 - 1.7e-15 57.9 0.0 2.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIM88286.1 - 3.9e-09 36.6 0.0 5.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EIM88286.1 - 6.2e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM88286.1 - 3e-06 27.8 0.0 5.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM88286.1 - 3.3e-06 27.7 0.0 7.6e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EIM88286.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TylF PF05711.11 EIM88286.1 - 0.014 14.7 0.0 0.04 13.2 0.0 1.5 1 1 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) Ubie_methyltran PF01209.18 EIM88286.1 - 0.028 13.7 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 EIM88286.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 EIM88286.1 - 0.055 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TRM PF02005.16 EIM88286.1 - 0.071 12.3 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Aldo_ket_red PF00248.21 EIM88287.1 - 2.3e-72 243.7 0.0 2.6e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 EIM88288.1 - 2.4e-10 40.1 0.4 1.6e-06 27.9 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.29 EIM88290.1 - 2.8e-30 105.7 0.0 4.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM88290.1 - 8.9e-05 22.2 0.4 0.00038 20.1 0.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase dsrm PF00035.26 EIM88293.1 - 0.00049 20.7 0.0 0.00056 20.6 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif RRP7 PF12923.7 EIM88294.1 - 1e-26 93.4 7.0 1e-26 93.4 7.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EIM88294.1 - 1.2e-08 35.0 0.0 4.3e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 EIM88294.1 - 6.8e-05 22.6 0.0 0.055 13.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 EIM88297.1 - 4.8e-39 133.9 0.1 8.4e-39 133.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM88297.1 - 3.2e-35 121.8 0.5 7.3e-35 120.6 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM88297.1 - 6.3e-09 36.0 0.3 1.2e-08 35.1 0.1 1.6 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.27 EIM88297.1 - 0.00032 21.2 0.5 0.0064 17.0 0.3 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EIM88297.1 - 0.00064 19.6 0.4 0.0053 16.7 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EIM88297.1 - 0.00094 18.4 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 EIM88297.1 - 0.012 15.6 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase YjeF_N PF03853.15 EIM88297.1 - 0.02 14.8 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF1776 PF08643.10 EIM88297.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RRM_1 PF00076.22 EIM88298.1 - 6.6e-32 109.2 0.0 4.4e-16 58.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIM88298.1 - 8.3e-06 25.8 0.0 2.7e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EIM88298.1 - 0.00019 21.4 0.0 0.00061 19.7 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EIM88298.1 - 0.0035 17.4 0.0 0.75 9.9 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 EIM88298.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGAP PF00616.19 EIM88299.1 - 2.4e-18 66.6 0.0 1.1e-14 54.7 0.0 2.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EIM88299.1 - 6.1e-10 39.4 0.2 1.8e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 EIM88299.1 - 0.00083 19.3 0.1 0.0027 17.6 0.1 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Scaffolding_pro PF11418.8 EIM88300.1 - 1.1 9.9 6.7 2.8 8.5 0.8 2.8 2 0 0 2 2 2 0 Phi29 scaffolding protein Spc7 PF08317.11 EIM88300.1 - 1.1 8.1 34.5 0.041 12.8 1.2 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein ABM PF03992.16 EIM88301.1 - 0.0016 18.5 0.2 0.0034 17.4 0.1 1.7 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase TPD52 PF04201.15 EIM88301.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Tumour protein D52 family zf-C2H2_4 PF13894.6 EIM88302.1 - 1.2e-18 66.2 42.1 0.018 15.8 0.2 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 EIM88302.1 - 1.3e-15 56.9 48.6 0.0021 18.4 0.1 8.6 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-met PF12874.7 EIM88302.1 - 2.2e-11 43.7 34.0 0.0054 17.1 3.2 7.2 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EIM88302.1 - 2.7e-11 43.4 47.6 7.9e-06 26.0 3.2 6.9 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EIM88302.1 - 0.0015 18.8 31.9 0.16 12.3 1.6 5.4 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EIM88302.1 - 0.0056 16.7 1.5 0.012 15.6 1.7 7.4 8 1 0 8 8 8 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIM88302.1 - 0.013 15.2 21.4 0.076 12.8 1.1 5.3 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 EIM88302.1 - 0.16 12.5 0.3 0.16 12.5 0.3 7.3 6 2 1 7 7 6 0 Zinc-finger double domain zf_ZIC PF18366.1 EIM88302.1 - 0.57 10.3 0.1 0.57 10.3 0.1 6.0 5 1 2 7 7 7 0 Zic proteins zinc finger domain zf_UBZ PF18439.1 EIM88302.1 - 0.87 9.2 31.2 0.47 10.1 1.2 6.3 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 EIM88302.1 - 2.5 7.8 22.8 0.71 9.5 1.1 5.3 3 2 2 5 5 5 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 EIM88302.1 - 3.2 8.6 19.5 3.7 8.4 4.1 4.1 2 1 2 4 4 4 0 zinc-ribbon family Isochorismatase PF00857.20 EIM88303.1 - 5.4e-31 108.1 0.0 7.6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family ATG16 PF08614.11 EIM88304.1 - 0.092 13.0 14.0 0.023 14.9 9.4 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SHE3 PF17078.5 EIM88304.1 - 1.2 8.8 4.1 0.71 9.5 0.2 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 EIM88304.1 - 1.5 8.1 10.6 0.77 9.1 7.4 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.9 EIM88304.1 - 2.8 7.8 8.7 0.88 9.5 0.2 2.5 1 1 0 2 2 2 0 Axonemal dynein light chain Pox_A_type_inc PF04508.12 EIM88304.1 - 7.5 6.6 7.5 55 3.8 0.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat PRKG1_interact PF15898.5 EIM88304.1 - 8.2 7.4 10.5 39 5.2 4.8 3.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain B12D PF06522.11 EIM88305.1 - 5.7e-15 54.9 0.2 7.9e-15 54.4 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.21 EIM88306.1 - 8.9e-42 143.3 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CBM_20 PF00686.19 EIM88307.1 - 1.4e-29 101.8 0.0 3.2e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 EIM88307.1 - 3.6e-13 49.8 0.0 3.3e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EIM88307.1 - 3.2e-11 43.5 0.5 2.9e-10 40.5 0.0 2.6 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EIM88307.1 - 0.066 13.6 0.0 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Thioredoxin PF00085.20 EIM88308.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pollen_Ole_e_I PF01190.17 EIM88308.1 - 0.017 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Pollen proteins Ole e I like DUF1479 PF07350.12 EIM88309.1 - 7.6e-129 430.1 0.0 8.8e-129 429.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EIM88309.1 - 0.00037 20.8 0.0 0.038 14.2 0.1 2.9 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) OMPdecase PF00215.24 EIM88310.1 - 7.4e-64 215.4 0.2 3.5e-42 144.5 0.0 2.1 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family PIN_4 PF13638.6 EIM88311.1 - 1.3e-18 67.5 0.0 2.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 PIN domain PIN PF01850.21 EIM88311.1 - 0.023 15.2 0.1 0.041 14.4 0.1 1.4 1 0 0 1 1 1 0 PIN domain PIN_12 PF16289.5 EIM88311.1 - 0.21 12.0 0.0 0.54 10.7 0.0 1.7 1 0 0 1 1 1 0 PIN domain Gly_transf_sug PF04488.15 EIM88312.1 - 6.9e-21 74.7 0.0 1.5e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4064 PF13273.6 EIM88312.1 - 0.016 15.5 1.2 0.13 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Nha1_C PF08619.10 EIM88312.1 - 0.017 14.3 0.8 0.023 13.9 0.8 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus MFS_1 PF07690.16 EIM88313.1 - 3.7e-30 105.1 22.7 9.4e-29 100.4 17.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM88313.1 - 1.8e-07 30.4 2.5 2.9e-07 29.7 1.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 EIM88313.1 - 0.0037 16.2 0.2 0.0069 15.4 0.2 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TruD PF01142.18 EIM88314.1 - 2.9e-76 257.0 0.0 8.8e-73 245.5 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) CTD_bind PF04818.13 EIM88315.1 - 0.0011 19.7 0.0 0.0029 18.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 EIM88315.1 - 0.0037 17.7 0.5 0.076 13.5 0.5 2.9 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 HNF-1_N PF04814.13 EIM88315.1 - 0.017 15.8 1.4 0.045 14.4 1.4 1.8 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus zf-C2H2_11 PF16622.5 EIM88315.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 EIM88315.1 - 0.19 12.3 2.8 7.6 7.1 0.3 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain SOG2 PF10428.9 EIM88315.1 - 5.1 6.2 26.9 0.29 10.3 20.9 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein Ribosomal_L6 PF00347.23 EIM88316.1 - 3.6e-27 94.8 1.5 1.9e-14 54.1 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ICMT PF04140.14 EIM88317.1 - 8.4e-27 93.4 1.3 1.4e-26 92.7 1.3 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM88317.1 - 7.9e-12 45.5 1.9 7.9e-12 45.5 1.9 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 EIM88317.1 - 2.3e-05 24.0 0.5 3.8e-05 23.3 0.5 1.4 1 0 0 1 1 1 1 NnrU protein ERG4_ERG24 PF01222.17 EIM88317.1 - 0.0012 17.7 0.3 0.0018 17.1 0.3 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TcpE PF12648.7 EIM88317.1 - 1.7 9.2 6.9 9.9 6.8 1.9 2.7 2 1 0 2 2 2 0 TcpE family GTP_EFTU PF00009.27 EIM88318.1 - 2e-50 171.0 0.0 3.6e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EIM88318.1 - 3.9e-15 55.6 0.1 4.3e-07 29.9 0.0 3.0 3 0 0 3 3 3 2 Elongation factor G C-terminus EFG_II PF14492.6 EIM88318.1 - 1.8e-11 44.0 0.0 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EIM88318.1 - 6.3e-06 26.5 0.0 2.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM88318.1 - 9.3e-05 22.5 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EIM88318.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 EIM88318.1 - 0.051 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 EIM88318.1 - 0.081 12.4 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 EIM88318.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ADH_N PF08240.12 EIM88319.1 - 8.7e-32 109.2 0.3 1.6e-31 108.4 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM88319.1 - 1.8e-21 76.5 0.1 2.8e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM88319.1 - 8.5e-07 30.1 0.0 1.5e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EIM88319.1 - 0.0071 17.0 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EIM88319.1 - 0.012 15.2 0.1 0.03 13.9 0.0 1.8 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EIM88319.1 - 0.063 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThrE PF06738.12 EIM88320.1 - 3.1e-51 174.1 13.3 1.1e-48 165.7 1.0 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM88320.1 - 5.8e-05 23.2 7.0 5.8e-05 23.2 7.0 2.6 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE Meth_synt_2 PF01717.18 EIM88321.1 - 6.4e-148 492.3 0.0 7.8e-144 478.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIM88321.1 - 2.7e-120 401.6 0.0 5e-113 377.7 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain VbhA PF18495.1 EIM88321.1 - 0.038 13.8 0.6 10 6.1 0.2 2.8 2 0 0 2 2 2 0 Antitoxin VbhA UPF0183 PF03676.14 EIM88322.1 - 1.3e-62 212.4 0.0 1.5e-62 212.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Hydrolase PF00702.26 EIM88323.1 - 1e-10 42.3 0.0 1.9e-09 38.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EIM88323.1 - 4.5e-08 33.4 0.0 9.3e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EIM88323.1 - 0.00041 19.9 0.1 0.9 9.0 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2608) HAD PF12710.7 EIM88323.1 - 0.0017 18.8 0.0 0.0025 18.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Globin PF00042.22 EIM88323.1 - 0.013 16.0 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 Globin Hydrolase_like PF13242.6 EIM88323.1 - 0.042 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L6e PF01159.19 EIM88324.1 - 1.1e-38 132.2 2.2 4.3e-38 130.3 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 EIM88324.1 - 0.00012 22.3 2.5 0.00012 22.2 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain 60KD_IMP PF02096.20 EIM88325.1 - 4.9e-08 33.1 0.0 6.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2919 PF11143.8 EIM88326.1 - 0.058 13.7 2.9 0.082 13.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) GAF_2 PF13185.6 EIM88326.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.6 1 1 1 2 2 2 0 GAF domain adh_short PF00106.25 EIM88327.1 - 5.8e-27 94.4 0.0 7.8e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM88327.1 - 5.5e-13 49.0 0.0 7.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM88327.1 - 9.8e-07 28.9 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM88327.1 - 0.00065 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EIM88327.1 - 0.003 16.9 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 EIM88327.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase NAD_Gly3P_dh_N PF01210.23 EIM88327.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EIM88327.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EIM88327.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Exog_C PF18026.1 EIM88327.1 - 0.046 13.8 0.2 0.091 12.8 0.2 1.4 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain ApbA PF02558.16 EIM88327.1 - 0.055 13.1 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA YjeF_N PF03853.15 EIM88327.1 - 0.059 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Helicase_RecD PF05127.14 EIM88327.1 - 0.088 12.7 0.1 0.25 11.2 0.1 1.8 1 1 0 1 1 1 0 Helicase NAD_binding_7 PF13241.6 EIM88327.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CRCB PF02537.15 EIM88328.1 - 2.9e-32 110.8 16.7 2.3e-19 69.5 7.1 2.2 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) CK_II_beta PF01214.18 EIM88329.1 - 1e-74 250.3 0.0 1.3e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit SDA1 PF05285.12 EIM88329.1 - 0.24 10.8 7.1 0.33 10.3 7.1 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EIM88329.1 - 0.3 10.4 6.6 0.41 9.9 6.6 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 EIM88329.1 - 1.5 8.9 8.6 2.4 8.2 8.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EIM88329.1 - 6.7 4.8 7.9 8.6 4.4 7.9 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EIM88329.1 - 7.4 4.5 13.7 9.6 4.2 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L36e PF01158.18 EIM88330.1 - 1.4e-38 131.0 5.0 1.6e-38 130.8 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 EIM88330.1 - 0.0054 16.6 0.1 0.0069 16.2 0.1 1.1 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold TPR_4 PF07721.14 EIM88331.1 - 0.11 13.2 0.2 0.59 10.9 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat KH_8 PF17903.1 EIM88332.1 - 9e-30 102.6 0.0 2.5e-29 101.2 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EIM88332.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EIM88332.1 - 0.056 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 KH domain NCBP3 PF10309.9 EIM88334.1 - 8.3e-11 41.6 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 EIM88334.1 - 0.013 16.1 0.2 0.013 16.1 0.2 3.3 3 1 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 DUF410 PF04190.13 EIM88335.1 - 8.7e-73 245.3 0.0 3e-72 243.5 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF410) Retrotran_gag_2 PF14223.6 EIM88335.1 - 0.018 14.7 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type HSBP1 PF06825.12 EIM88336.1 - 2.9e-20 71.8 2.7 3.6e-20 71.5 2.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 EIM88336.1 - 0.07 13.0 0.0 0.62 10.0 0.0 2.0 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin FdhE PF04216.12 EIM88336.1 - 0.15 12.0 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Terpene_synth_C PF03936.16 EIM88338.1 - 2.4e-07 30.4 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ank_4 PF13637.6 EIM88339.1 - 2.7e-15 56.5 0.1 2.2e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EIM88339.1 - 2.9e-13 49.6 1.0 0.0011 19.4 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EIM88339.1 - 3.9e-13 49.3 1.8 0.00015 22.0 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM88339.1 - 9.2e-13 48.6 0.0 7.2e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIM88339.1 - 1.5e-11 43.5 0.3 0.0021 18.4 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Chorion_S16 PF05836.12 EIM88339.1 - 0.13 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Chorion protein S16 Ank_4 PF13637.6 EIM88340.1 - 3.5e-17 62.5 0.0 4.3e-11 43.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM88340.1 - 1.6e-10 41.4 0.0 2.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIM88340.1 - 2.9e-10 40.1 0.4 1.7e-07 31.4 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EIM88340.1 - 1e-09 38.5 0.0 5.9e-06 26.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM88340.1 - 6.3e-09 35.4 0.0 1.8e-05 24.7 0.0 2.3 3 0 0 3 3 3 2 Ankyrin repeat MYEOV2 PF15004.6 EIM88341.1 - 0.098 13.1 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 Myeloma-overexpressed-like F-box-like PF12937.7 EIM88343.1 - 1.2e-06 28.3 0.4 1.2e-06 28.3 0.4 2.8 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EIM88343.1 - 0.046 14.2 7.8 5.8 7.5 0.2 4.6 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM88343.1 - 0.095 12.5 3.4 15 5.4 0.0 4.3 5 0 0 5 5 5 0 Leucine rich repeat ADH_N PF08240.12 EIM88344.1 - 0.0023 17.8 0.3 0.0052 16.7 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain JmjC PF02373.22 EIM88345.1 - 1.4e-15 57.7 1.9 5.4e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase Zf_RING PF16744.5 EIM88345.1 - 0.012 15.7 2.0 0.035 14.2 2.0 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger FYVE PF01363.21 EIM88345.1 - 0.39 10.9 11.0 0.02 15.0 4.6 2.2 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_2 PF14445.6 EIM88345.1 - 6.4 7.0 12.1 1.5 9.1 4.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Response_reg PF00072.24 EIM88346.1 - 1.2e-22 80.2 0.2 8.2e-17 61.4 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain ARS2 PF04959.13 EIM88347.1 - 1.5e-15 58.1 0.3 1.5e-15 58.1 0.3 3.6 3 1 0 3 3 3 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 EIM88347.1 - 6.1e-15 55.4 1.6 6.1e-15 55.4 1.6 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EIM88347.1 - 0.00097 18.9 0.5 0.0022 17.7 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 EIM88347.1 - 0.028 14.9 1.5 0.06 13.8 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRM_1 PF00076.22 EIM88348.1 - 5.6e-05 22.9 0.0 0.0085 15.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADAM_spacer1 PF05986.14 EIM88348.1 - 0.099 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 TFIID-18kDa PF02269.16 EIM88349.1 - 1.1e-26 92.7 0.6 2.4e-26 91.6 0.2 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 EIM88349.1 - 0.022 15.1 2.9 0.022 15.1 2.9 1.9 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF1931 PF09123.11 EIM88349.1 - 0.055 13.6 0.1 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) Atg29_N PF18388.1 EIM88350.1 - 3.6e-15 55.5 1.3 6.7e-15 54.7 1.3 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain Adeno_terminal PF02459.15 EIM88350.1 - 0.35 9.2 0.7 0.52 8.6 0.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Herpes_pp85 PF04637.12 EIM88350.1 - 2.6 6.3 3.7 4.5 5.6 3.7 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Zn_clus PF00172.18 EIM88351.1 - 0.0012 18.9 5.7 0.0023 18.0 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0029 PF01205.19 EIM88352.1 - 7.7e-30 103.3 0.0 8.7e-29 99.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EIM88352.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain Aldedh PF00171.22 EIM88353.1 - 4.3e-161 536.5 2.4 4.9e-161 536.3 2.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TFIIS_M PF07500.14 EIM88353.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Ldh_2 PF02615.14 EIM88353.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase CDC14 PF08045.11 EIM88354.1 - 1.8e-37 129.0 0.4 4.4e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 Cell division control protein 14, SIN component Cyt-b5 PF00173.28 EIM88355.1 - 2.8e-22 78.6 0.0 3.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tropomyosin_1 PF12718.7 EIM88356.1 - 0.02 15.0 16.3 0.22 11.7 0.4 2.6 2 0 0 2 2 2 0 Tropomyosin like Shugoshin_N PF07558.11 EIM88356.1 - 0.034 14.0 1.9 0.077 12.9 0.1 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Vac_Fusion PF02346.16 EIM88356.1 - 0.096 12.3 1.1 0.26 10.9 1.1 1.7 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 CENP-H PF05837.12 EIM88356.1 - 0.48 10.9 10.9 0.77 10.2 4.8 3.2 2 1 0 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.6 EIM88356.1 - 0.61 10.1 15.4 0.12 12.4 8.0 2.8 2 0 0 2 2 2 0 FlxA-like protein TPR_MLP1_2 PF07926.12 EIM88356.1 - 1.6 8.8 15.8 1.1 9.3 8.2 2.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Leu_zip PF15294.6 EIM88356.1 - 4.8 6.6 11.3 2 7.9 0.2 2.3 2 0 0 2 2 2 0 Leucine zipper HIG_1_N PF04588.13 EIM88357.1 - 2.8e-05 24.2 2.1 6.9e-05 23.0 2.1 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MFS_MOT1 PF16983.5 EIM88357.1 - 0.052 13.9 0.5 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Surp PF01805.20 EIM88357.1 - 0.14 12.2 0.1 0.87 9.6 0.0 2.3 2 0 0 2 2 2 0 Surp module Ofd1_CTDD PF10637.9 EIM88359.1 - 1.3e-75 254.0 0.0 2e-73 246.9 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EIM88359.1 - 4.6e-31 107.3 0.0 1.3e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EIM88359.1 - 1.2e-14 54.9 0.0 5.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOA36 PF06524.12 EIM88359.1 - 2.2 7.6 8.6 4.5 6.5 8.6 1.4 1 0 0 1 1 1 0 NOA36 protein Prothymosin PF03247.14 EIM88359.1 - 6.5 7.3 23.7 3 8.4 14.0 2.9 2 0 0 2 2 2 0 Prothymosin/parathymosin family Cwf_Cwc_15 PF04889.12 EIM88359.1 - 6.5 6.4 11.0 14 5.3 11.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FMN_dh PF01070.18 EIM88360.1 - 5.6e-111 370.9 0.0 7.1e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EIM88360.1 - 1.3e-17 63.7 0.0 2.7e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 EIM88360.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EIM88360.1 - 0.0044 16.1 0.5 0.033 13.2 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EIM88360.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase NIF PF03031.18 EIM88361.1 - 1.1e-44 152.0 0.0 1.3e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCHC PF00098.23 EIM88362.1 - 0.00026 20.9 28.3 0.0045 17.0 1.0 4.5 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_2 PF13696.6 EIM88362.1 - 0.036 13.9 0.8 0.036 13.9 0.8 3.9 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIM88362.1 - 0.74 9.8 30.5 1.2 9.2 2.2 5.1 2 1 3 5 5 5 0 Zinc knuckle DUF5421 PF17458.2 EIM88362.1 - 6.8 6.0 8.7 17 4.7 8.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5421) MFS_1 PF07690.16 EIM88364.1 - 1.6e-37 129.2 42.4 1.8e-36 125.8 34.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Snf7 PF03357.21 EIM88365.1 - 2.2e-36 125.1 20.1 2.2e-36 125.1 20.1 1.9 1 1 1 2 2 2 1 Snf7 Ribosomal_60s PF00428.19 EIM88365.1 - 0.0018 18.8 8.9 0.0045 17.5 3.4 2.8 2 1 1 3 3 3 1 60s Acidic ribosomal protein Mob1_phocein PF03637.17 EIM88367.1 - 1.5e-78 262.6 0.0 1.8e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.29 EIM88369.1 - 1.5e-42 145.4 0.0 2.6e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM88369.1 - 2.6e-24 85.7 0.0 6.8e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM88369.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HMG_box PF00505.19 EIM88371.1 - 2.6e-11 43.8 0.1 3.2e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM88371.1 - 0.0007 20.1 0.1 0.00082 19.9 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EIM88371.1 - 0.029 13.7 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box PLD_C PF12357.8 EIM88371.1 - 0.092 12.7 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Phospholipase D C terminal Sua5_yciO_yrdC PF01300.18 EIM88372.1 - 4.3e-54 182.7 0.0 9.5e-54 181.6 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EIM88372.1 - 1.6e-29 103.1 0.0 2.9e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Opy2 PF09463.10 EIM88373.1 - 4.8e-05 23.6 17.7 7.5e-05 23.0 17.7 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 EIM88373.1 - 0.16 11.4 0.3 0.39 10.2 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PepSY_TM PF03929.16 EIM88373.1 - 1.1 8.8 4.9 0.32 10.6 0.5 2.1 2 1 0 2 2 2 0 PepSY-associated TM region CorA PF01544.18 EIM88375.1 - 1.6e-37 129.4 10.6 4.6e-34 118.1 7.9 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein APH PF01636.23 EIM88376.1 - 0.00022 21.3 0.6 0.0004 20.4 0.6 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family CorA PF01544.18 EIM88377.1 - 1.9e-37 129.2 8.2 1.6e-32 113.0 7.1 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SOBP PF15279.6 EIM88377.1 - 0.077 13.6 4.5 0.13 12.9 4.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Pyridoxal_deC PF00282.19 EIM88378.1 - 1.2e-99 333.6 0.0 5.1e-99 331.5 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain HTH_8 PF02954.19 EIM88378.1 - 0.092 12.5 0.1 31 4.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family NMT1 PF09084.11 EIM88379.1 - 0.065 13.2 0.0 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 NMT1/THI5 like MFS_1 PF07690.16 EIM88380.1 - 3.5e-24 85.4 32.1 7.4e-24 84.3 32.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Na_Ca_ex PF01699.24 EIM88380.1 - 0.56 10.2 0.0 0.56 10.2 0.0 3.5 3 2 0 3 3 3 0 Sodium/calcium exchanger protein Con-6 PF10346.9 EIM88381.1 - 1.8e-14 53.4 0.1 2.7e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Conidiation protein 6 Sod_Fe_C PF02777.18 EIM88383.1 - 1.8e-09 37.7 0.0 0.0012 18.9 0.1 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DAD PF02109.16 EIM88384.1 - 1.3e-47 160.6 3.6 1.5e-47 160.4 3.6 1.0 1 0 0 1 1 1 1 DAD family TMEM154 PF15102.6 EIM88384.1 - 0.019 14.9 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF1748 PF08520.10 EIM88385.1 - 3.4e-26 90.9 0.0 3.8e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) F-box-like PF12937.7 EIM88388.1 - 9.4e-06 25.4 1.3 2.9e-05 23.9 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM88388.1 - 2.1e-05 24.3 0.7 4.6e-05 23.2 0.7 1.6 1 0 0 1 1 1 1 F-box domain Proteasome PF00227.26 EIM88389.1 - 6.3e-55 185.6 0.0 7.6e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIM88389.1 - 1.1e-12 47.3 0.1 1.1e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cyt-b5 PF00173.28 EIM88392.1 - 8.9e-11 41.8 0.1 1.7e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.19 EIM88393.1 - 1.8e-34 118.6 0.0 1.2e-33 115.8 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 EIM88393.1 - 1.1e-13 51.1 0.0 3.7e-07 30.1 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_A4 PF01828.17 EIM88395.1 - 9.5e-80 267.0 19.7 1.2e-79 266.7 19.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family ORC6 PF05460.13 EIM88396.1 - 0.019 14.3 0.3 0.024 13.9 0.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAP1 PF07218.11 EIM88396.1 - 2.1 6.5 3.3 2.4 6.3 3.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Wtap PF17098.5 EIM88398.1 - 4.2e-18 65.8 8.6 4.2e-18 65.8 8.6 2.4 2 1 0 2 2 2 1 WTAP/Mum2p family SKA1 PF07160.12 EIM88398.1 - 0.0076 16.1 3.1 0.0076 16.1 3.1 2.7 2 1 1 3 3 3 1 Spindle and kinetochore-associated protein 1 ALMT PF11744.8 EIM88398.1 - 0.14 11.0 4.6 0.17 10.6 4.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PKcGMP_CC PF16808.5 EIM88398.1 - 0.21 11.5 5.6 5.5 6.9 0.9 3.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PRA-PH PF01503.17 EIM88398.1 - 0.35 11.3 2.2 0.34 11.4 0.2 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase SlyX PF04102.12 EIM88398.1 - 0.43 11.2 4.9 24 5.7 0.1 3.5 2 1 1 3 3 3 0 SlyX TFIIA PF03153.13 EIM88398.1 - 0.47 10.4 16.2 0.75 9.7 16.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.11 EIM88398.1 - 0.91 8.3 13.6 1.1 8.0 13.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3915 PF13054.6 EIM88398.1 - 3.5 7.6 8.1 7.2 6.6 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Zn_ribbon_SprT PF17283.2 EIM88400.1 - 0.11 12.4 3.0 3.6 7.6 0.6 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Ank_2 PF12796.7 EIM88401.1 - 2.6e-22 79.2 0.0 1.8e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM88401.1 - 1.5e-20 73.2 1.8 1.9e-11 44.2 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIM88401.1 - 1.3e-19 70.0 0.8 4.3e-10 39.7 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM88401.1 - 1.9e-13 49.3 0.2 0.00033 20.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EIM88401.1 - 9.9e-13 47.9 0.2 4e-06 27.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat MFS_1 PF07690.16 EIM88402.1 - 3.1e-11 42.8 25.1 2.3e-09 36.7 27.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EIM88402.1 - 7.1e-05 21.8 4.4 7.1e-05 21.8 4.4 2.0 2 1 0 2 2 2 1 MFS_1 like family Diphthami_syn_2 PF01902.17 EIM88403.1 - 2.4e-39 135.1 0.0 6.1e-37 127.2 0.0 2.1 1 1 0 1 1 1 1 Diphthamide synthase Asparaginase_C PF17763.1 EIM88403.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain tRNA_synthFbeta PF17759.1 EIM88404.1 - 1.1e-50 172.0 0.0 5.4e-50 169.8 0.0 1.9 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EIM88404.1 - 7.5e-33 112.6 0.1 1.4e-31 108.5 0.0 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EIM88404.1 - 5.3e-26 91.3 0.2 1e-25 90.4 0.2 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EIM88404.1 - 2.6e-17 62.9 0.0 7.5e-15 55.0 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 EIM88404.1 - 0.0058 16.1 0.1 0.072 12.6 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) Say1_Mug180 PF10340.9 EIM88405.1 - 1.3e-18 67.0 0.0 2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EIM88405.1 - 8.3e-16 58.5 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold SNARE_assoc PF09335.11 EIM88407.1 - 1.3e-18 67.6 5.1 2.9e-18 66.5 5.1 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein tRNA-synt_2d PF01409.20 EIM88408.1 - 1.9e-83 279.7 0.0 4.9e-55 186.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EIM88408.1 - 3.3e-16 59.3 0.8 9.2e-16 57.9 0.2 2.1 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EIM88408.1 - 1.9e-09 37.3 0.0 0.00019 20.9 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EIM88408.1 - 4.9e-05 23.2 2.0 0.00014 21.8 2.0 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 EIM88408.1 - 0.0011 18.1 0.1 0.029 13.5 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EIM88408.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD1 PF18552.1 EIM88408.1 - 0.16 11.7 0.1 11 5.9 0.1 2.5 2 0 0 2 2 2 0 PheRS DNA binding domain 1 Acetyltransf_1 PF00583.25 EIM88409.1 - 2.8e-09 37.2 0.0 6.8e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM88409.1 - 3.3e-06 27.4 0.0 6.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM88409.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EIM88409.1 - 6.5e-05 23.6 0.0 0.017 15.8 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM88409.1 - 0.00081 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAP PF07174.11 EIM88411.1 - 6.4 6.1 12.1 0.079 12.4 4.7 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) DUF2370 PF10176.9 EIM88412.1 - 2.8e-73 246.3 0.0 5.7e-73 245.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) Abhydrolase_3 PF07859.13 EIM88413.1 - 1.1e-19 71.2 0.0 1.5e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM88413.1 - 5.1e-15 55.2 0.0 7.8e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 EIM88413.1 - 0.033 14.0 0.0 0.074 12.8 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PX PF00787.24 EIM88414.1 - 9.6e-27 93.2 0.0 1.2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 EIM88416.1 - 8.4e-62 205.1 2.3 7.9e-22 77.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EIM88416.1 - 4.5e-05 22.7 0.0 0.0025 17.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EIM88416.1 - 7.6e-05 22.3 0.0 0.002 17.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EIM88416.1 - 0.00037 20.9 0.0 0.00078 19.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EIM88416.1 - 0.0077 15.7 0.8 0.031 13.8 0.1 2.2 2 0 0 2 2 2 1 EF hand DivIC PF04977.15 EIM88417.1 - 0.0083 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Septum formation initiator AKNA PF12443.8 EIM88417.1 - 0.031 14.9 0.1 0.066 13.9 0.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor Prefoldin_2 PF01920.20 EIM88417.1 - 0.062 13.3 0.2 0.095 12.7 0.2 1.2 1 0 0 1 1 1 0 Prefoldin subunit Snapin_Pallidin PF14712.6 EIM88417.1 - 0.08 13.4 0.2 0.12 12.8 0.2 1.2 1 0 0 1 1 1 0 Snapin/Pallidin DUF3740 PF12548.8 EIM88417.1 - 0.088 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Sulfatase protein GIT_CC PF16559.5 EIM88417.1 - 0.12 12.2 0.8 0.19 11.6 0.8 1.2 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fez1 PF06818.15 EIM88418.1 - 0.0012 19.3 22.7 0.0012 19.3 22.7 5.0 1 1 2 4 4 4 1 Fez1 TFIIF_alpha PF05793.12 EIM88419.1 - 2e-18 66.3 45.8 7.7e-09 34.7 38.6 4.1 2 1 1 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTB PF00651.31 EIM88420.1 - 4.4e-06 26.9 0.0 6.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain WD40_4 PF16300.5 EIM88420.1 - 0.18 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 Type of WD40 repeat HLH PF00010.26 EIM88421.1 - 3.6e-07 30.0 0.3 7.6e-07 29.0 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.29 EIM88422.1 - 4.4e-05 23.9 0.1 0.0012 19.3 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM88422.1 - 5.6e-05 23.6 0.0 0.00023 21.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EIM88422.1 - 0.00069 19.6 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 EIM88422.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 EIM88422.1 - 0.08 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EIM88422.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Med20 PF08612.11 EIM88423.1 - 5.8e-08 32.4 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Pkinase PF00069.25 EIM88425.1 - 6.5e-65 219.1 0.2 9e-44 149.8 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88425.1 - 3.3e-28 98.7 0.2 6.7e-21 74.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM88425.1 - 1.1e-07 31.1 0.1 1.6e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIM88425.1 - 0.00081 18.8 0.3 0.0026 17.1 0.0 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM88425.1 - 0.0012 18.8 0.3 0.045 13.7 0.3 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM88425.1 - 0.0014 18.0 0.2 0.012 14.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EIM88425.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_C PF00433.24 EIM88425.1 - 0.022 15.4 0.3 0.051 14.3 0.3 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 EIM88425.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EIM88425.1 - 0.053 12.3 0.7 0.11 11.3 0.3 1.5 1 1 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EIM88425.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3818 PF12825.7 EIM88426.1 - 2e-127 424.9 0.1 2e-127 424.9 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EIM88426.1 - 3e-30 104.9 0.3 7.6e-30 103.6 0.3 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EIM88426.1 - 8.3e-10 38.6 0.6 3.7e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 PX domain YL1 PF05764.13 EIM88426.1 - 0.0042 17.2 11.9 0.0042 17.2 11.9 2.5 2 0 0 2 2 2 1 YL1 nuclear protein Nop14 PF04147.12 EIM88426.1 - 0.062 11.5 11.6 0.12 10.6 11.6 1.4 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 EIM88426.1 - 1.8 6.2 4.7 3.1 5.5 4.7 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 EIM88426.1 - 7.4 5.8 15.4 17 4.6 15.4 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1682 PF07946.14 EIM88428.1 - 3.5e-91 305.8 0.5 4.4e-91 305.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RNA_pol_Rpc4 PF05132.14 EIM88428.1 - 0.76 10.2 6.2 1.2 9.6 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cgr1 PF03879.14 EIM88428.1 - 1.2 9.6 25.3 1.9 8.9 25.3 1.3 1 0 0 1 1 1 0 Cgr1 family 2-oxoacid_dh PF00198.23 EIM88430.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF2721 PF11026.8 EIM88430.1 - 0.3 11.0 0.8 0.64 9.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Nop14 PF04147.12 EIM88430.1 - 2.1 6.5 7.8 4.4 5.4 7.8 1.4 1 0 0 1 1 1 0 Nop14-like family LON_substr_bdg PF02190.16 EIM88431.1 - 3.4e-22 79.4 0.0 5.1e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EIM88431.1 - 1.3e-13 50.5 12.1 2.8e-13 49.5 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIM88431.1 - 8.9e-10 38.3 4.9 8.9e-10 38.3 4.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM88431.1 - 4.8e-09 36.1 8.0 6e-09 35.8 6.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EIM88431.1 - 9.8e-09 35.4 10.9 2.3e-08 34.2 10.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM88431.1 - 1.1e-08 34.7 11.5 2.5e-08 33.7 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM88431.1 - 9.7e-08 31.9 11.4 1.8e-07 31.0 11.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM88431.1 - 4.6e-07 29.6 7.6 9.8e-07 28.5 7.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EIM88431.1 - 7.8e-06 26.0 12.0 1.8e-05 24.8 12.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EIM88431.1 - 1.1e-05 25.4 3.8 2.1e-05 24.6 3.8 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EIM88431.1 - 0.00045 20.5 7.9 0.0011 19.3 7.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EIM88431.1 - 0.0013 18.4 2.9 0.0028 17.4 2.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EIM88431.1 - 0.0023 17.5 5.3 0.0053 16.4 5.3 1.6 1 0 0 1 1 1 1 P-11 zinc finger zf-ANAPC11 PF12861.7 EIM88431.1 - 0.027 14.5 2.9 0.056 13.5 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EIM88431.1 - 0.25 11.3 6.9 0.045 13.6 2.5 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 EIM88431.1 - 0.64 10.1 5.2 1.6 8.9 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) G6PD_C PF02781.16 EIM88432.1 - 4.9e-110 367.3 0.0 7.3e-110 366.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EIM88432.1 - 6.1e-61 206.1 0.0 9.6e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain UQ_con PF00179.26 EIM88433.1 - 4.5e-39 133.3 0.2 5.5e-39 133.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme McrBC PF10117.9 EIM88433.1 - 0.084 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component RWD PF05773.22 EIM88433.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 RWD domain Metallophos PF00149.28 EIM88438.1 - 1.2e-09 39.0 0.5 2.2e-09 38.1 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RFX_DNA_binding PF02257.15 EIM88439.1 - 1.7e-27 95.8 0.0 3.4e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain NuDC PF16273.5 EIM88439.1 - 0.2 12.2 0.7 0.44 11.1 0.7 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain Ribosomal_L7Ae PF01248.26 EIM88440.1 - 1.5e-23 82.4 0.2 1.5e-23 82.4 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cupin_8 PF13621.6 EIM88441.1 - 4.7e-52 177.2 0.0 7.5e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EIM88441.1 - 0.0035 17.8 0.4 0.12 12.8 0.0 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EIM88441.1 - 0.025 14.3 0.5 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.12 EIM88441.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein ORC4_C PF14629.6 EIM88443.1 - 2.7e-29 102.1 0.0 4.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EIM88443.1 - 1.7e-16 61.1 0.1 3.8e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EIM88443.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EIM88443.1 - 0.011 16.1 0.0 0.069 13.6 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EIM88443.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EIM88443.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EIM88443.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 EIM88443.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_14 PF13173.6 EIM88443.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EIM88443.1 - 0.19 12.1 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 EIM88443.1 - 0.2 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein Nodulin PF02451.15 EIM88443.1 - 1.1 8.7 3.7 0.83 9.1 0.1 2.2 2 0 0 2 2 2 0 Nodulin DUF3759 PF12585.8 EIM88444.1 - 4e-38 129.3 7.7 4.8e-38 129.1 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) TetR_C_31 PF17940.1 EIM88444.1 - 0.022 15.0 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ThrE PF06738.12 EIM88445.1 - 5.7e-50 169.9 15.4 7.1e-50 169.6 1.3 2.3 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM88445.1 - 7.4e-06 26.1 6.7 7.4e-06 26.1 6.7 2.7 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF829 PF05705.14 EIM88446.1 - 1.1e-31 110.7 0.0 1.3e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 EIM88446.1 - 0.02 14.5 0.0 0.047 13.2 0.1 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3336 PF11815.8 EIM88447.1 - 1.9e-49 166.9 1.7 2.8e-49 166.4 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EIM88447.1 - 1.7e-17 64.3 0.1 4.9e-17 62.8 0.1 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase TadE PF07811.12 EIM88447.1 - 0.28 11.5 2.0 0.63 10.4 2.0 1.5 1 0 0 1 1 1 0 TadE-like protein Pkinase_fungal PF17667.1 EIM88449.1 - 4.7e-31 108.0 0.0 4.7e-11 42.1 0.0 3.4 2 1 1 3 3 3 3 Fungal protein kinase Phage_holin_1 PF04531.13 EIM88449.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin MIF4G PF02854.19 EIM88449.1 - 0.17 11.5 0.4 0.35 10.5 0.1 1.6 2 0 0 2 2 2 0 MIF4G domain PCI PF01399.27 EIM88450.1 - 6e-11 42.8 0.0 1.9e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EIM88450.1 - 0.021 14.5 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 MarR_2 PF12802.7 EIM88450.1 - 0.024 14.5 0.4 7.7 6.5 0.1 3.2 3 0 0 3 3 3 0 MarR family TAFH PF07531.14 EIM88450.1 - 0.048 13.8 0.1 6.7 6.9 0.0 3.2 3 0 0 3 3 3 0 NHR1 homology to TAF FeoC PF09012.10 EIM88450.1 - 0.099 12.7 0.1 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator Pkinase PF00069.25 EIM88451.1 - 8.9e-77 258.0 0.0 1.1e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88451.1 - 1.5e-37 129.3 0.1 4.1e-37 127.9 0.0 1.7 2 1 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM88451.1 - 1.3e-07 31.2 0.0 2.6e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIM88451.1 - 3.3e-05 23.0 0.0 0.005 15.8 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EIM88451.1 - 0.017 13.9 0.0 0.043 12.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EIM88451.1 - 0.032 13.6 0.4 0.1 12.0 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 EIM88452.1 - 9.5e-18 64.2 6.0 4.8e-08 33.5 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88452.1 - 0.00039 20.7 0.0 0.0037 17.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Asp PF00026.23 EIM88453.1 - 1.3e-108 363.2 0.2 1.5e-108 362.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM88453.1 - 2.4e-15 57.2 2.3 5.4e-13 49.6 2.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EIM88453.1 - 5.1e-05 23.1 0.0 0.0012 18.7 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EIM88453.1 - 0.0001 22.9 0.1 0.3 11.8 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EIM88453.1 - 0.0015 19.1 0.0 1.8 9.2 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Bromodomain PF00439.25 EIM88454.1 - 8.9e-21 73.8 0.2 1.7e-20 72.8 0.2 1.4 1 0 0 1 1 1 1 Bromodomain VID27 PF08553.10 EIM88455.1 - 1.6e-165 550.4 0.2 2.2e-165 550.0 0.2 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EIM88455.1 - 2.3e-55 187.1 0.5 2.3e-55 187.1 0.5 2.5 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EIM88455.1 - 1.1e-14 54.7 0.0 5e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 VID27 PH-like domain IFT57 PF10498.9 EIM88455.1 - 0.043 12.8 2.2 0.073 12.0 2.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RTA1 PF04479.13 EIM88456.1 - 2.4e-54 184.1 7.6 5e-54 183.1 6.3 1.8 2 0 0 2 2 2 1 RTA1 like protein BTB_2 PF02214.22 EIM88457.1 - 0.077 13.4 0.2 0.34 11.3 0.0 2.1 3 0 0 3 3 3 0 BTB/POZ domain Rpr2 PF04032.16 EIM88458.1 - 0.0035 17.6 0.2 0.006 16.8 0.2 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.6 EIM88458.1 - 0.013 14.9 1.8 0.96 9.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.12 EIM88458.1 - 0.15 11.9 3.6 0.34 10.7 0.4 2.3 2 0 0 2 2 2 0 HypF finger TF_Zn_Ribbon PF08271.12 EIM88458.1 - 0.36 10.4 1.1 3.5 7.2 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding RNB PF00773.19 EIM88459.1 - 2.1e-100 336.3 0.1 4.1e-100 335.3 0.1 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 EIM88459.1 - 7.4e-26 90.3 0.2 2.5e-25 88.6 0.2 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EIM88459.1 - 6.9e-25 86.9 0.0 1.6e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EIM88459.1 - 0.00014 21.9 0.0 0.075 13.2 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EIM88459.1 - 0.0033 17.2 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EIM88459.1 - 0.0064 16.4 0.5 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 S1 domain Iso_dh PF00180.20 EIM88460.1 - 2.6e-99 332.7 0.0 3.1e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.18 EIM88461.1 - 1.6e-18 66.7 0.0 2.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM88461.1 - 1.5e-05 25.0 10.0 2.5e-05 24.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L5e PF17144.4 EIM88462.1 - 1.7e-81 272.0 0.1 2.9e-81 271.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EIM88462.1 - 9.4e-34 116.2 4.6 9.4e-34 116.2 4.6 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region MtrA PF04208.14 EIM88462.1 - 0.032 13.9 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A DUF5388 PF17363.2 EIM88462.1 - 0.14 12.4 0.0 0.69 10.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5388) RRM_1 PF00076.22 EIM88463.1 - 2.6e-15 56.0 0.0 3.9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPAM_1 PF08139.12 EIM88464.1 - 1.6 9.4 3.3 1 10.0 1.1 1.8 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site WH2 PF02205.20 EIM88465.1 - 1.7e-05 24.5 2.8 5.1e-05 23.0 1.2 2.5 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.20 EIM88466.1 - 6.7e-58 193.1 0.1 1.7e-30 105.0 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EIM88466.1 - 1.8e-39 135.5 0.0 6.6e-31 107.6 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 EIM88466.1 - 7e-07 29.2 0.5 0.0061 16.5 0.1 2.7 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 EIM88466.1 - 1e-06 28.8 0.1 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EIM88466.1 - 1.6e-06 28.6 0.3 0.15 12.5 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 EIM88466.1 - 2.7e-06 27.2 0.9 0.11 12.2 0.1 3.3 3 0 0 3 3 3 3 Redoxin Thioredoxin_8 PF13905.6 EIM88466.1 - 3.6e-06 27.2 0.1 0.019 15.3 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like Calsequestrin PF01216.17 EIM88466.1 - 1.7e-05 24.0 0.6 2.8e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Calsequestrin OST3_OST6 PF04756.13 EIM88466.1 - 7.5e-05 22.2 0.0 0.0069 15.8 0.0 2.9 2 1 1 3 3 3 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EIM88466.1 - 0.18 12.1 0.9 6.1 7.1 0.0 2.8 2 1 0 2 2 2 0 Glutaredoxin TCTP PF00838.17 EIM88467.1 - 1.2e-75 253.4 1.4 1.3e-75 253.3 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UTP15_C PF09384.10 EIM88468.1 - 2.4e-50 170.0 0.0 3.7e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EIM88468.1 - 4.5e-25 87.4 10.2 3e-05 24.7 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88468.1 - 1.6e-10 41.1 0.0 0.0093 16.2 0.0 4.8 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EIM88468.1 - 2.1e-06 26.5 0.5 0.00019 20.1 0.0 2.6 2 1 1 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 EIM88468.1 - 0.0054 16.1 0.0 0.46 9.8 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 EIM88468.1 - 0.036 14.6 0.5 1.8 9.1 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain Nup160 PF11715.8 EIM88468.1 - 0.1 11.2 0.5 3 6.4 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 CTNNBL PF08216.11 EIM88469.1 - 1.1e-34 118.7 0.0 3.6e-34 117.1 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear MOR2-PAG1_C PF14225.6 EIM88469.1 - 0.081 12.8 0.2 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Acetyltransf_3 PF13302.7 EIM88471.1 - 4.5e-11 43.6 0.1 5.3e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM88471.1 - 1.1e-09 38.5 0.1 1.3e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EIM88471.1 - 3e-09 37.2 0.1 3.2e-09 37.1 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM88471.1 - 2.3e-08 34.4 0.1 2.7e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM88471.1 - 6.6e-05 22.9 0.0 7.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_18 PF00704.28 EIM88472.1 - 2.7e-50 171.9 0.0 3.2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TRAM_LAG1_CLN8 PF03798.16 EIM88473.1 - 8.5e-36 123.6 24.9 8.5e-36 123.6 24.9 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EIM88473.1 - 2.6e-18 65.4 2.4 5e-18 64.5 0.1 2.6 3 0 0 3 3 3 1 TRAM1-like protein NPC1_N PF16414.5 EIM88474.1 - 1.7e-81 273.4 3.9 2.9e-81 272.6 3.9 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EIM88474.1 - 1.8e-67 228.1 7.1 3.4e-37 128.0 0.0 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 EIM88474.1 - 1.2e-44 151.8 14.5 3.4e-24 85.4 0.1 3.6 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EIM88474.1 - 9.5e-05 20.3 7.1 9.5e-05 20.3 7.1 1.8 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Cyclin PF08613.11 EIM88475.1 - 0.00024 21.5 0.0 0.00042 20.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Amidohydro_2 PF04909.14 EIM88476.1 - 1.1e-08 35.3 0.0 2e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EIM88476.1 - 2.7e-07 30.2 0.0 4.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Kinesin PF00225.23 EIM88477.1 - 1.9e-107 359.1 0.0 2.9e-107 358.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIM88477.1 - 2.6e-25 89.1 0.0 5e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Peptidase_C58 PF03543.14 EIM88477.1 - 7.9 6.1 5.9 0.92 9.2 0.3 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen EMP24_GP25L PF01105.24 EIM88478.1 - 6.3e-52 176.2 0.2 7.3e-52 175.9 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RE_R_Pab1 PF09522.10 EIM88478.1 - 0.15 12.2 0.2 0.33 11.1 0.1 1.6 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease AAA_2 PF07724.14 EIM88479.1 - 1.1e-36 126.5 0.0 1.8e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EIM88479.1 - 4.8e-15 56.2 0.0 1.2e-14 54.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EIM88479.1 - 1.4e-08 34.7 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 EIM88479.1 - 3.1e-06 26.7 0.1 0.0036 16.7 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIM88479.1 - 1.1e-05 25.5 0.0 3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 EIM88479.1 - 6e-05 22.3 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EIM88479.1 - 7.4e-05 22.5 0.0 0.0023 17.6 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 EIM88479.1 - 9.7e-05 22.7 0.1 0.0039 17.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM88479.1 - 0.0019 18.6 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 EIM88479.1 - 0.0043 16.9 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIM88479.1 - 0.0082 15.7 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 EIM88479.1 - 0.0091 16.1 0.0 0.029 14.5 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 EIM88479.1 - 0.0091 15.7 0.1 0.15 11.8 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EIM88479.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 EIM88479.1 - 0.012 16.2 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EIM88479.1 - 0.022 15.3 0.2 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EIM88479.1 - 0.026 13.6 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EIM88479.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIM88479.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EIM88479.1 - 0.081 13.1 0.8 0.23 11.6 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_14 PF13173.6 EIM88479.1 - 0.085 12.9 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EIM88479.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 EIM88479.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 EIM88479.1 - 0.099 12.9 0.0 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EIM88479.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase TsaE PF02367.17 EIM88479.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 EIM88479.1 - 0.12 11.5 1.3 0.77 8.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EIM88479.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 EIM88479.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIM88479.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 EIM88479.1 - 0.18 11.9 0.2 0.85 9.7 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 EIM88479.1 - 0.21 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cactin_mid PF10312.9 EIM88480.1 - 8.7e-66 221.4 5.1 8.7e-66 221.4 5.1 3.1 3 1 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EIM88480.1 - 3.3e-60 201.5 6.6 7e-60 200.5 6.6 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EIM88480.1 - 0.061 13.7 0.0 0.63 10.4 0.0 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) HycA_repressor PF11046.8 EIM88481.1 - 0.014 15.6 0.3 0.025 14.8 0.3 1.3 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons JAB PF01398.21 EIM88482.1 - 4.8e-33 113.6 0.2 8.1e-33 112.9 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EIM88482.1 - 3.4e-14 53.2 1.1 5.6e-14 52.5 1.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EIM88482.1 - 4e-07 29.8 0.0 6.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 EIM88482.1 - 0.0042 17.2 0.1 0.0074 16.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) UPF0172 PF03665.13 EIM88482.1 - 0.073 13.1 2.2 0.13 12.3 0.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.20 EIM88483.1 - 5.9e-14 52.0 0.1 7e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 HalOD1 PF18545.1 EIM88483.1 - 0.05 13.9 0.0 0.097 13.0 0.0 1.5 1 1 1 2 2 2 0 Halobacterial output domain 1 Pkinase PF00069.25 EIM88484.1 - 4.6e-61 206.5 0.0 5.5e-41 140.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88484.1 - 1.8e-27 96.3 0.0 4.3e-22 78.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EIM88484.1 - 6e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EIM88484.1 - 6.2e-08 32.3 0.1 0.00058 19.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIM88484.1 - 0.0013 18.7 2.1 0.002 18.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 EIM88484.1 - 0.0016 18.6 0.0 0.0049 17.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain FTA2 PF13095.6 EIM88484.1 - 0.0026 17.4 0.1 0.66 9.6 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EIM88484.1 - 0.0097 14.9 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIM88484.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EIM88484.1 - 0.053 12.6 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EIM88484.1 - 0.069 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family OKR_DC_1_N PF03709.15 EIM88484.1 - 0.21 11.8 0.4 0.54 10.5 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Pkinase_fungal PF17667.1 EIM88484.1 - 0.45 9.2 1.8 0.94 8.2 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase Suc_Fer-like PF06999.12 EIM88487.1 - 4.2e-50 170.3 0.0 5.3e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pkinase PF00069.25 EIM88488.1 - 2.4e-66 223.8 0.0 3.2e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88488.1 - 2.4e-29 102.4 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EIM88488.1 - 1.4e-16 60.9 1.8 5.6e-16 59.0 0.3 2.7 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EIM88488.1 - 5.7e-09 36.2 0.5 2.3e-06 27.8 0.2 2.5 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 EIM88488.1 - 8.1e-08 31.9 0.0 1.5e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EIM88488.1 - 3.3e-06 26.3 0.1 3.3e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 EIM88488.1 - 0.0012 18.5 0.1 0.22 11.1 0.1 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIM88488.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM88488.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM88488.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1935 PF09149.10 EIM88489.1 - 0.088 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Forkhead PF00250.18 EIM88490.1 - 3.9e-30 103.9 0.0 6.1e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain CIAPIN1 PF05093.13 EIM88491.1 - 2.1e-30 105.2 4.4 3.7e-30 104.4 4.4 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EIM88491.1 - 2.5e-05 24.5 0.0 3.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Med18 PF09637.10 EIM88492.1 - 1.7e-09 37.9 0.0 4.2e-08 33.3 0.0 2.0 1 1 1 2 2 2 2 Med18 protein Cyclin PF08613.11 EIM88493.1 - 0.0046 17.3 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin ThiF PF00899.21 EIM88494.1 - 3.4e-106 354.1 0.0 4.9e-69 232.4 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EIM88494.1 - 2.8e-88 296.1 0.0 4.8e-88 295.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EIM88494.1 - 1.4e-34 118.1 0.4 2.6e-34 117.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EIM88494.1 - 2e-31 108.6 0.3 4.4e-31 107.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EIM88494.1 - 4.6e-25 87.6 0.3 1.2e-24 86.3 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 EIM88494.1 - 0.013 15.6 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3402 PF11882.8 EIM88495.1 - 2.7e-118 396.0 3.0 4.6e-117 392.0 3.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EIM88495.1 - 7.2e-66 222.3 0.0 1.2e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Lipase_chap PF03280.14 EIM88496.1 - 0.11 12.5 2.1 0.22 11.5 2.1 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein OmpH PF03938.14 EIM88497.1 - 0.033 14.5 4.8 0.047 14.0 4.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rhabdo_glycop PF00974.18 EIM88497.1 - 0.17 10.3 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF948 PF06103.11 EIM88497.1 - 0.47 10.8 1.9 3.8 7.8 1.9 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GAS2 PF02187.17 EIM88498.1 - 3.1e-12 46.4 0.1 8.1e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Gp58 PF07902.11 EIM88498.1 - 0.022 13.1 0.0 0.022 13.1 0.0 2.0 2 0 0 2 2 2 0 gp58-like protein Retrotrans_gag PF03732.17 EIM88498.1 - 0.4 11.0 4.4 3 8.2 0.0 4.4 4 0 0 4 4 4 0 Retrotransposon gag protein Bestrophin PF01062.21 EIM88499.1 - 5.8e-35 121.1 0.0 1.1e-19 70.9 0.1 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Golgin_A5 PF09787.9 EIM88500.1 - 0.013 15.0 2.7 0.017 14.6 2.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4472 PF14739.6 EIM88500.1 - 0.014 16.1 0.4 0.025 15.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) zf-C3HC4_3 PF13920.6 EIM88500.1 - 0.047 13.6 0.5 0.46 10.4 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIM88500.1 - 0.067 13.0 0.7 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PriA_CRR PF18319.1 EIM88500.1 - 0.2 11.7 3.6 4.2 7.4 0.4 2.7 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain DZR PF12773.7 EIM88500.1 - 0.2 11.7 3.5 1.1 9.3 0.5 2.6 3 0 0 3 3 3 0 Double zinc ribbon zf-RING_5 PF14634.6 EIM88500.1 - 0.31 11.0 5.2 0.099 12.6 1.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain DUF4715 PF15835.5 EIM88500.1 - 0.33 11.0 2.8 0.58 10.2 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) PKcGMP_CC PF16808.5 EIM88500.1 - 0.5 10.3 4.4 0.32 10.9 0.9 2.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 EIM88500.1 - 4 8.1 6.7 32 5.2 6.7 2.1 1 1 0 1 1 1 0 SlyX Aconitase PF00330.20 EIM88502.1 - 1.9e-158 528.3 0.0 2.3e-158 528.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIM88502.1 - 1.5e-38 132.1 0.0 2.4e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain ALF PF03752.13 EIM88502.1 - 3.7 7.6 4.9 21 5.2 0.2 2.4 2 0 0 2 2 2 0 Short repeats of unknown function Ribosomal_L29e PF01779.17 EIM88503.1 - 5e-21 74.7 12.0 6.3e-21 74.4 12.0 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Tau95 PF09734.9 EIM88504.1 - 3e-39 135.0 2.2 8.2e-39 133.6 1.0 2.2 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EIM88504.1 - 7.3e-31 107.0 0.0 2e-30 105.6 0.0 1.8 2 0 0 2 2 2 1 Tau95 Triple barrel domain Sld5 PF05916.11 EIM88506.1 - 0.0022 18.5 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Pkr1 PF08636.10 EIM88507.1 - 1.1e-10 41.5 3.4 1.1e-10 41.5 3.4 1.8 2 0 0 2 2 2 1 ER protein Pkr1 DUF2244 PF10003.9 EIM88507.1 - 0.18 11.5 1.1 0.28 10.9 1.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PagP PF07017.11 EIM88507.1 - 0.21 11.0 0.0 0.57 9.6 0.0 1.7 2 0 0 2 2 2 0 Antimicrobial peptide resistance and lipid A acylation protein PagP MDM10 PF12519.8 EIM88508.1 - 3.7e-99 332.7 0.3 2.7e-88 296.9 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EIM88508.1 - 0.016 14.7 0.1 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic porin Diphthamide_syn PF01866.17 EIM88509.1 - 4.2e-93 312.1 0.0 7.3e-55 186.5 0.0 2.7 2 1 0 2 2 2 2 Putative diphthamide synthesis protein DUF1378 PF07125.11 EIM88509.1 - 0.089 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Fungal_trans PF04082.18 EIM88510.1 - 2.2e-25 89.2 0.2 3.9e-25 88.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain M-factor PF03855.13 EIM88510.1 - 1.3 9.3 3.2 1.9 8.7 1.7 2.1 1 1 0 1 1 1 0 M-factor Cry1Ac_D5 PF17997.1 EIM88512.1 - 0.11 12.3 0.3 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 Sugar_tr PF00083.24 EIM88513.1 - 3e-114 382.4 18.4 3.6e-114 382.1 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM88513.1 - 6.1e-25 87.9 52.8 1.1e-23 83.7 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATE_C PF04377.15 EIM88514.1 - 3.6e-44 150.6 0.2 5.7e-44 150.0 0.2 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EIM88514.1 - 3.5e-28 97.8 4.0 8.1e-28 96.6 4.0 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus WD40 PF00400.32 EIM88515.1 - 0.00024 21.8 0.0 0.23 12.4 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88515.1 - 0.053 13.8 0.0 4.7 7.6 0.0 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EIM88515.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) FXMR_C2 PF16098.5 EIM88515.1 - 0.13 12.8 0.6 0.28 11.7 0.6 1.5 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 EF-hand_7 PF13499.6 EIM88517.1 - 7.7e-27 93.5 6.5 1.8e-17 63.5 0.9 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EIM88517.1 - 1.4e-24 83.8 10.5 5.3e-08 31.9 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EIM88517.1 - 3e-21 73.5 7.7 1.4e-06 27.8 0.2 5.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EIM88517.1 - 6.7e-14 51.5 6.4 3.4e-06 26.8 0.6 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EIM88517.1 - 1.5e-12 46.4 7.9 0.00093 18.6 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 EIM88517.1 - 2.8e-07 30.4 5.3 0.038 13.9 0.0 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EIM88517.1 - 9.9e-05 22.6 3.5 0.09 13.1 0.4 3.6 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EIM88517.1 - 0.00044 20.5 3.3 1.2 9.5 0.6 3.4 2 1 1 3 3 3 2 EF-hand domain Caleosin PF05042.13 EIM88517.1 - 0.032 14.2 3.0 9.4 6.1 0.0 3.2 2 1 1 3 3 3 0 Caleosin related protein Pan3_PK PF18101.1 EIM88517.1 - 0.042 13.8 0.2 0.073 13.0 0.2 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain S10_plectin PF03501.15 EIM88517.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_14 PF17959.1 EIM88517.1 - 0.37 11.2 2.0 0.97 9.8 0.5 2.6 2 1 0 2 2 2 0 EF-hand domain EMC3_TMCO1 PF01956.16 EIM88518.1 - 1.2e-39 135.7 0.0 1.6e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Sec63 PF02889.16 EIM88519.1 - 1.7e-73 246.9 0.0 2.6e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EIM88519.1 - 1.2e-35 122.8 0.9 5.4e-22 78.4 0.8 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EIM88519.1 - 1.6e-15 57.5 0.0 1.7e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM88519.1 - 5.9e-07 29.8 0.1 4.8e-05 23.7 0.0 3.8 4 1 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EIM88519.1 - 0.00013 22.3 0.0 0.73 10.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 EIM88519.1 - 0.00037 20.9 0.1 0.54 10.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIM88519.1 - 0.095 12.2 0.0 2.8 7.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EIM88519.1 - 0.11 11.5 0.1 0.69 8.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Aminotran_1_2 PF00155.21 EIM88520.1 - 1.8e-65 221.5 0.0 2.1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIM88520.1 - 1.8e-06 27.5 0.0 3.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EIM88520.1 - 1.4e-05 23.8 0.0 3.8e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EIM88520.1 - 0.00037 19.9 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EIM88520.1 - 0.0031 16.5 0.0 0.074 12.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V F-box-like PF12937.7 EIM88521.1 - 0.00095 19.0 0.1 0.003 17.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like NAD_binding_6 PF08030.12 EIM88523.1 - 2.7e-19 69.8 0.0 4.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EIM88523.1 - 3.8e-15 56.1 13.2 3.8e-15 56.1 13.2 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIM88523.1 - 2e-14 53.6 0.0 4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FYVE PF01363.21 EIM88524.1 - 9.6e-18 64.1 10.6 9.6e-18 64.1 10.6 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EIM88524.1 - 7.7e-09 35.8 3.9 7.7e-09 35.8 3.9 4.2 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 EIM88524.1 - 3.7e-06 26.7 2.6 3.7e-06 26.7 2.6 4.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM88524.1 - 0.0002 21.0 3.9 0.00073 19.2 3.9 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EIM88524.1 - 0.00092 19.4 4.2 0.00092 19.4 4.2 3.1 4 1 0 4 4 3 1 RING-H2 zinc finger domain FANCL_C PF11793.8 EIM88524.1 - 0.0024 18.0 2.5 0.0024 18.0 2.5 2.9 4 1 0 4 4 3 1 FANCL C-terminal domain zf-RING_9 PF13901.6 EIM88524.1 - 0.0024 17.9 0.7 0.0024 17.9 0.7 3.7 4 0 0 4 4 4 1 Putative zinc-RING and/or ribbon zf-RING_UBOX PF13445.6 EIM88524.1 - 0.0035 17.3 3.8 0.0035 17.3 3.8 4.1 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING-like PF08746.11 EIM88524.1 - 0.059 13.7 2.2 0.059 13.7 2.2 3.7 3 1 1 4 4 3 0 RING-like domain FYVE_2 PF02318.16 EIM88524.1 - 0.11 12.7 17.3 0.033 14.4 8.9 2.9 2 1 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.6 EIM88524.1 - 0.22 11.5 26.9 0.2 11.6 3.4 3.8 3 1 1 4 4 4 0 zinc-RING finger domain zf-tcix PF14952.6 EIM88524.1 - 7 6.4 10.9 0.51 10.0 2.2 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding Baculo_PP31 PF05311.11 EIM88525.1 - 0.012 15.1 0.9 0.028 13.9 0.9 1.5 1 1 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PI31_Prot_N PF11566.8 EIM88526.1 - 2.4e-45 154.2 0.0 3e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EIM88526.1 - 8.6e-13 49.3 15.7 8.6e-13 49.3 15.7 3.2 3 0 0 3 3 3 1 PI31 proteasome regulator DEAD PF00270.29 EIM88527.1 - 6.7e-52 175.8 0.0 1.2e-50 171.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM88527.1 - 9.7e-27 93.5 0.0 4e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM88527.1 - 0.001 19.1 0.0 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NuDC PF16273.5 EIM88527.1 - 0.07 13.7 4.0 0.11 13.1 0.0 2.7 2 0 0 2 2 2 0 Nuclear distribution C domain MFS_1 PF07690.16 EIM88528.1 - 3.9e-41 141.2 42.5 3.9e-41 141.2 42.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM88528.1 - 0.00022 20.2 24.2 0.0073 15.2 23.4 3.7 1 1 0 1 1 1 1 Sugar (and other) transporter Nup88 PF10168.9 EIM88529.1 - 3.6e-25 87.9 6.1 1.2e-11 43.2 4.5 3.0 2 1 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 EIM88529.1 - 0.00022 21.3 7.3 0.00022 21.3 7.3 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 ANAPC4_WD40 PF12894.7 EIM88529.1 - 0.034 14.4 0.0 17 5.8 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 EIM88530.1 - 3.4e-47 160.4 0.0 4.1e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIM88530.1 - 1.9e-13 49.8 0.1 3.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CSN8_PSD8_EIF3K PF10075.9 EIM88531.1 - 1.6e-29 102.7 0.0 3.3e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EIM88531.1 - 2.5e-06 27.1 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 EIM88532.1 - 1.5e-38 132.2 0.0 1.7e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Nsp1_C PF05064.13 EIM88534.1 - 7.7e-32 109.5 0.1 9.9e-31 106.0 0.1 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EIM88534.1 - 1.2e-11 45.3 134.5 3.5e-08 34.2 33.2 6.3 1 1 5 6 6 6 5 Nucleoporin FG repeat region CENP-Q PF13094.6 EIM88534.1 - 0.0079 16.4 7.2 0.045 14.0 7.2 2.0 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Laminin_II PF06009.12 EIM88534.1 - 0.019 15.0 1.7 0.52 10.3 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 EIM88534.1 - 0.06 13.7 3.7 9 6.8 0.2 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DHR10 PF18595.1 EIM88534.1 - 0.21 11.6 3.9 0.091 12.8 1.5 1.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 EIM88534.1 - 1 10.0 8.1 7 7.3 0.3 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal AAA_13 PF13166.6 EIM88534.1 - 1 7.9 3.9 7.2 5.1 1.2 1.8 1 1 1 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 EIM88534.1 - 1.4 9.0 4.5 14 5.8 4.3 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EIM88534.1 - 1.5 9.3 5.3 0.64 10.5 1.9 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc24 PF08286.11 EIM88534.1 - 2.5 8.4 5.0 4.3 7.6 2.1 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UbiA PF01040.18 EIM88535.1 - 6.4e-53 179.6 13.7 7.9e-53 179.3 13.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ytp1 PF10355.9 EIM88536.1 - 3.7e-107 357.7 8.3 5.1e-107 357.2 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EIM88536.1 - 5.7e-14 51.8 0.3 5.7e-14 51.8 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF1129 PF06570.11 EIM88536.1 - 0.0093 15.5 0.3 0.16 11.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1129) SK_channel PF03530.14 EIM88536.1 - 0.27 11.2 1.0 0.61 10.1 0.1 2.0 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Packaging_FI PF14000.6 EIM88536.1 - 0.28 11.6 1.7 0.45 11.0 1.7 1.2 1 0 0 1 1 1 0 DNA packaging protein FI DUF1056 PF06341.11 EIM88536.1 - 3.1 8.2 6.4 4.4 7.7 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) MFS_1 PF07690.16 EIM88537.1 - 9.6e-35 120.1 14.4 3e-34 118.5 14.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EIM88537.1 - 2.9e-06 26.8 1.0 2.9e-06 26.8 1.0 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 EIM88537.1 - 3.6 7.2 9.0 15 5.2 2.3 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Rho_GDI PF02115.17 EIM88538.1 - 4.4e-49 166.9 0.0 5.1e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor zf-CCHH PF10283.9 EIM88539.1 - 0.19 11.7 7.3 5.5 7.1 0.2 3.0 2 0 0 2 2 2 0 PBZ domain TrkH PF02386.16 EIM88539.1 - 0.22 9.9 0.2 0.29 9.5 0.2 1.1 1 0 0 1 1 1 0 Cation transport protein Toxin_19 PF08088.12 EIM88539.1 - 7.7 6.7 13.4 1.4 9.1 6.8 2.4 2 0 0 2 2 2 0 Conotoxin I-superfamily PRKG1_interact PF15898.5 EIM88540.1 - 0.13 13.1 0.0 0.22 12.4 0.0 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain zf-CCCH PF00642.24 EIM88540.1 - 0.26 11.3 19.9 0.088 12.7 2.0 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIM88541.1 - 0.0087 16.1 0.6 0.017 15.2 0.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EIM88541.1 - 0.0096 15.8 1.9 0.018 14.9 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2064 PF09837.9 EIM88541.1 - 0.067 13.0 0.3 1.7 8.5 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) GFO_IDH_MocA PF01408.22 EIM88542.1 - 1.2e-16 61.6 0.1 2.1e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EIM88542.1 - 1.3e-06 28.4 0.0 6.5e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain LpxK PF02606.14 EIM88542.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Sclerostin PF05463.11 EIM88542.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) DUF448 PF04296.13 EIM88543.1 - 0.02 14.8 0.0 0.17 11.8 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF448) EAF PF09816.9 EIM88544.1 - 1.1e-18 67.5 0.1 2.4e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Ferritin_2 PF13668.6 EIM88545.1 - 2.6e-32 111.9 2.5 2.6e-32 111.9 2.5 1.8 2 0 0 2 2 2 1 Ferritin-like domain ENT PF03735.14 EIM88545.1 - 0.13 12.3 0.0 0.61 10.2 0.0 2.0 1 1 0 1 1 1 0 ENT domain Peptidase_S10 PF00450.22 EIM88546.1 - 1.3e-101 341.0 0.2 1.7e-101 340.7 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nop PF01798.18 EIM88547.1 - 9.7e-85 283.7 0.1 1.8e-84 282.8 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EIM88547.1 - 9.2e-20 70.8 0.3 2.8e-19 69.2 0.3 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Pex2_Pex12 PF04757.14 EIM88548.1 - 3.6e-31 108.5 4.5 5.1e-31 108.0 4.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 EIM88548.1 - 0.00023 21.0 0.6 0.00023 21.0 0.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EIM88548.1 - 0.0013 18.8 0.9 0.0034 17.5 0.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EIM88548.1 - 0.0051 16.8 0.7 0.0051 16.8 0.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM88548.1 - 0.0051 16.6 1.9 0.0099 15.7 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM88548.1 - 0.046 13.6 3.6 0.081 12.8 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM88548.1 - 0.084 13.2 5.6 0.093 13.1 1.6 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 EIM88548.1 - 0.17 11.7 4.1 0.37 10.7 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.19 EIM88549.1 - 1.6e-12 47.2 1.9 4.6e-12 45.7 0.2 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EIM88549.1 - 0.0039 17.3 2.9 0.0083 16.2 0.0 3.1 4 0 0 4 4 4 1 Exportin 1-like protein DUF3385 PF11865.8 EIM88549.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Slx4 PF09494.10 EIM88550.1 - 1.6e-05 24.7 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Prok-RING_2 PF14445.6 EIM88550.1 - 0.17 12.1 0.1 0.42 10.8 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Mur_ligase_M PF08245.12 EIM88551.1 - 0.0003 20.8 0.0 0.22 11.5 0.0 2.7 1 1 1 2 2 2 2 Mur ligase middle domain MgtE PF01769.16 EIM88552.1 - 0.31 11.4 4.2 0.16 12.4 1.3 2.0 2 0 0 2 2 2 0 Divalent cation transporter Vps52 PF04129.12 EIM88553.1 - 6.5e-60 203.3 0.6 8.1e-42 143.6 0.0 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 EIM88553.1 - 5.2e-07 28.5 0.0 0.013 14.0 0.0 3.1 2 1 1 3 3 3 2 Exocyst complex component Sec3 PrkA PF06798.12 EIM88553.1 - 0.093 12.3 0.3 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain KCH PF16944.5 EIM88554.1 - 1e-92 310.5 14.6 1.2e-92 310.2 14.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel FAM163 PF15069.6 EIM88554.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 FAM163 family MMR_HSR1_Xtn PF16897.5 EIM88555.1 - 4.5e-37 126.3 0.4 1.1e-36 125.1 0.4 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EIM88555.1 - 5.4e-24 84.0 0.0 1.2e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EIM88555.1 - 4.4e-21 75.1 0.0 9.7e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM88555.1 - 7.3e-09 35.3 0.2 1.7e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EIM88555.1 - 0.015 14.3 0.7 0.031 13.2 0.2 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EIM88555.1 - 0.035 14.2 0.6 13 5.9 0.5 2.6 1 1 1 2 2 2 0 Dynamin family PemK_toxin PF02452.17 EIM88555.1 - 0.087 13.2 0.1 0.26 11.7 0.1 2.0 1 1 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Alg6_Alg8 PF03155.15 EIM88556.1 - 5.6e-163 543.4 28.5 1.6e-162 541.9 28.5 1.6 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family 4HBT PF03061.22 EIM88557.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EIM88557.1 - 4.6e-06 26.1 0.1 0.00012 21.4 0.2 2.0 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 EIM88557.1 - 0.00066 20.2 0.0 0.00091 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily VMA21 PF09446.10 EIM88558.1 - 8.1e-12 45.1 5.0 1.3e-11 44.4 5.0 1.3 1 0 0 1 1 1 1 VMA21-like domain Acetyltransf_1 PF00583.25 EIM88559.1 - 6.3e-08 32.9 0.0 8.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EIM88559.1 - 1.8e-07 31.4 0.0 1.6e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EIM88559.1 - 2.1e-07 31.7 0.0 2.6e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM88559.1 - 0.00019 21.8 0.1 0.0003 21.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM88559.1 - 0.00027 20.9 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EIM88559.1 - 0.00044 20.2 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM88559.1 - 0.0016 18.6 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 EIM88559.1 - 0.006 16.2 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Ribonuc_red_sm PF00268.21 EIM88560.1 - 2.7e-123 410.9 0.8 3.5e-123 410.5 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EIM88560.1 - 0.17 12.8 0.0 0.35 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Ribonuc_red_sm PF00268.21 EIM88561.1 - 4e-120 400.5 0.4 4.8e-120 400.2 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuclease_3 PF00636.26 EIM88562.1 - 3.3e-41 140.2 0.0 1.9e-19 70.2 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIM88562.1 - 4.2e-23 81.9 0.0 4e-12 46.4 0.0 4.4 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EIM88562.1 - 3.1e-12 46.5 0.0 1.1e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.22 EIM88562.1 - 2.3e-08 33.9 0.0 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Helicase_C PF00271.31 EIM88562.1 - 1.8e-05 25.0 0.0 4.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tox-REase-3 PF15647.6 EIM88562.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 COX7C PF02935.16 EIM88563.1 - 2.2e-13 50.3 0.6 2.5e-13 50.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.22 EIM88564.1 - 2.9e-177 589.8 0.1 3.3e-177 589.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.18 EIM88565.1 - 8.2e-06 25.8 5.9 1.2e-05 25.4 5.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 EIM88566.1 - 3.8e-61 205.9 0.0 5.8e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIM88566.1 - 2.6e-08 33.4 0.2 7.5e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.21 EIM88567.1 - 9.5e-32 109.5 0.0 1.2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIM88567.1 - 3.2e-14 52.9 0.0 4.5e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EIM88567.1 - 2.4e-10 40.1 0.0 4.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssu72 PF04722.13 EIM88568.1 - 1.4e-76 256.3 0.0 1.6e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SNARE_assoc PF09335.11 EIM88569.1 - 7.2e-15 55.5 7.8 7.2e-15 55.5 7.8 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein Cys_Met_Meta_PP PF01053.20 EIM88570.1 - 8.1e-56 189.2 0.0 1.9e-54 184.7 0.0 2.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DPBB_1 PF03330.18 EIM88571.1 - 5.9e-06 26.5 0.0 9.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase WD40 PF00400.32 EIM88572.1 - 1e-53 178.1 28.3 1.6e-07 31.9 0.1 12.4 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88572.1 - 2.8e-22 78.8 4.9 3.8e-05 23.9 0.0 8.9 5 2 4 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EIM88572.1 - 5.5e-14 52.4 0.4 1e-13 51.5 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EIM88572.1 - 2.2e-08 33.4 3.8 0.0092 15.0 0.1 6.4 4 2 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EIM88572.1 - 9.2e-08 31.2 9.9 0.0028 16.4 0.5 5.1 4 3 1 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EIM88572.1 - 2.8e-05 23.0 1.9 1.3 7.7 0.1 5.1 4 1 2 6 6 6 2 Nup133 N terminal like WD40_like PF17005.5 EIM88572.1 - 4.3e-05 23.0 0.0 0.37 10.1 0.0 4.1 4 1 0 4 4 4 1 WD40-like domain Glyco_hydro_28 PF00295.17 EIM88572.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 Peptidase_M18 PF02127.15 EIM88573.1 - 8.5e-156 519.1 0.0 9.9e-156 518.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EIM88573.1 - 0.0013 17.8 0.0 0.24 10.4 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Acyl-CoA_dh_M PF02770.19 EIM88573.1 - 0.04 14.1 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Brix PF04427.18 EIM88574.1 - 2.6e-31 109.2 1.3 3.7e-31 108.8 1.3 1.2 1 0 0 1 1 1 1 Brix domain SMK-1 PF04802.15 EIM88575.1 - 3.4e-79 265.1 0.0 5.2e-79 264.5 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 EVE PF01878.18 EIM88575.1 - 8.2e-45 152.4 0.1 1.7e-44 151.4 0.1 1.5 1 0 0 1 1 1 1 EVE domain MIT PF04212.18 EIM88575.1 - 0.029 14.5 0.1 0.063 13.3 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF1992 PF09350.10 EIM88576.1 - 3.5e-22 78.3 0.1 8.7e-22 77.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RhoGEF PF00621.20 EIM88577.1 - 4.3e-17 62.9 0.0 4.8e-07 30.2 0.0 3.3 3 0 0 3 3 3 3 RhoGEF domain DUF5310 PF17237.2 EIM88578.1 - 2.6e-18 65.6 5.3 3.7e-18 65.1 5.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Syntaxin PF00804.25 EIM88579.1 - 1.1e-21 77.4 3.5 1.8e-21 76.7 3.5 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EIM88579.1 - 7.3e-08 32.3 2.7 7.3e-08 32.3 2.7 2.7 3 0 0 3 3 3 1 SNARE domain LMBR1 PF04791.16 EIM88579.1 - 0.0058 15.6 0.7 0.0075 15.2 0.7 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF2207 PF09972.9 EIM88579.1 - 0.015 14.1 0.9 0.03 13.1 0.1 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 EIM88579.1 - 0.018 15.3 0.3 0.055 13.8 0.3 1.8 1 0 0 1 1 1 0 Orf78 (ac78) PBP1_TM PF14812.6 EIM88579.1 - 0.051 14.0 0.1 0.051 14.0 0.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3394 PF11874.8 EIM88579.1 - 0.18 11.5 1.8 0.26 10.9 0.4 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3394) MFS_Mycoplasma PF07672.13 EIM88579.1 - 0.19 11.0 3.4 0.37 10.0 3.4 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter T7SS_ESX_EspC PF10824.8 EIM88579.1 - 0.31 11.6 0.1 0.31 11.6 0.1 3.2 3 1 1 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm Use1 PF09753.9 EIM88579.1 - 0.32 10.7 5.2 0.6 9.8 5.2 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 FUSC PF04632.12 EIM88579.1 - 0.35 9.3 3.7 5 5.5 0.7 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family RIFIN PF02009.16 EIM88579.1 - 0.49 10.2 6.9 0.97 9.3 1.6 2.0 1 1 1 2 2 2 0 Rifin Sigma_reg_N PF13800.6 EIM88579.1 - 2.1 8.7 4.2 3.5 8.0 2.7 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF720 PF05302.11 EIM88579.1 - 4.3 7.2 7.5 0.81 9.5 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF720) VPS28 PF03997.12 EIM88580.1 - 7.6e-71 237.7 0.0 8.7e-71 237.5 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Oxidored_FMN PF00724.20 EIM88581.1 - 2.8e-94 316.2 0.0 3.2e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4050 PF13259.6 EIM88582.1 - 0.00013 22.3 0.1 0.061 13.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4050) F-box-like PF12937.7 EIM88583.1 - 1.5e-09 37.6 2.5 1.5e-09 37.6 2.5 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM88583.1 - 3.6e-08 33.6 9.7 0.014 15.8 0.1 7.4 5 1 2 7 7 7 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EIM88583.1 - 0.0042 17.0 18.6 34 4.8 0.0 9.1 10 0 0 10 10 10 0 Leucine Rich repeat F-box PF00646.33 EIM88583.1 - 0.0057 16.5 0.8 0.018 14.9 0.8 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 EIM88583.1 - 0.32 11.7 3.7 25 6.0 0.1 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 EIM88583.1 - 2.1 8.2 10.0 0.55 10.0 0.2 4.0 5 0 0 5 5 5 0 Leucine rich repeat SAM_Ste50p PF09235.10 EIM88583.1 - 6.9 7.0 6.5 13 6.1 0.0 4.0 4 1 1 5 5 5 0 Ste50p, sterile alpha motif Lipase_GDSL PF00657.22 EIM88584.1 - 2.1e-10 40.9 0.0 3.7e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIM88584.1 - 7.2e-08 33.0 0.1 1.1e-07 32.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Tubulin PF00091.25 EIM88585.1 - 6.2e-67 225.6 0.0 8.3e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIM88585.1 - 1.1e-46 158.1 0.0 1.7e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EIM88585.1 - 8.3e-05 22.3 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 EIM88586.1 - 7.8e-65 218.8 0.0 1e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIM88586.1 - 8.4e-49 164.9 0.0 1.4e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EIM88586.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 EIM88586.1 - 0.07 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Dimer_Tnp_hAT PF05699.14 EIM88588.1 - 3e-06 26.9 0.2 0.0066 16.2 0.0 3.0 2 1 1 3 3 3 2 hAT family C-terminal dimerisation region Abhydrolase_3 PF07859.13 EIM88589.1 - 4.1e-35 121.6 0.1 1.1e-27 97.3 0.1 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM88589.1 - 3.1e-07 29.6 0.0 3.7e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EIM88589.1 - 0.031 13.2 0.0 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Carboxylesterase family DUF2264 PF10022.9 EIM88590.1 - 1.6e-140 468.2 0.1 2e-140 467.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DSPc PF00782.20 EIM88591.1 - 7.8e-27 93.7 0.0 9e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TAF4 PF05236.14 EIM88593.1 - 5.6e-35 121.4 0.2 8.1e-35 120.9 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family PAF-AH_p_II PF03403.13 EIM88594.1 - 1.6e-36 125.7 0.0 2.3e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 EIM88594.1 - 0.0027 18.4 0.5 0.0027 18.4 0.5 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM88594.1 - 0.0043 16.3 0.0 0.96 8.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EIM88594.1 - 0.0054 15.7 0.0 0.089 11.7 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EIM88594.1 - 0.06 12.4 0.0 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase tRNA-synt_1c PF00749.21 EIM88595.1 - 1.2e-107 359.5 0.0 1.6e-107 359.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EIM88595.1 - 1.4e-39 135.7 0.2 2.2e-39 135.1 0.2 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EIM88595.1 - 1e-32 113.4 0.0 2.2e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EIM88595.1 - 3.5e-07 31.1 1.7 1e-06 29.6 1.7 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 p450 PF00067.22 EIM88596.1 - 2.2e-62 211.3 0.0 3.8e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 SET PF00856.28 EIM88597.1 - 0.00078 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 SET domain Glyco_hydro_43 PF04616.14 EIM88598.1 - 8.2e-44 150.1 8.3 1e-43 149.7 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pex14_N PF04695.13 EIM88599.1 - 2.8e-09 37.8 4.1 1e-08 36.0 0.0 3.0 3 1 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Amidase PF01425.21 EIM88601.1 - 6e-54 183.7 0.0 2e-53 182.0 0.0 1.7 1 1 0 1 1 1 1 Amidase SKN1 PF03935.15 EIM88603.1 - 5.1e-191 635.4 9.9 5.9e-191 635.2 9.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TFR_dimer PF04253.15 EIM88605.1 - 1.7e-20 73.3 2.0 1.1e-19 70.7 0.0 2.7 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EIM88605.1 - 1e-14 54.7 0.0 3e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EIM88605.1 - 4.9e-09 36.1 0.1 1.2e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 PA domain Alpha-amylase_C PF02806.18 EIM88606.1 - 6.7e-23 81.0 0.0 2.5e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EIM88606.1 - 2.3e-18 66.3 0.1 8.9e-18 64.4 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EIM88606.1 - 3.2e-13 50.0 0.0 1.3e-09 38.1 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain SANT_DAMP1_like PF16282.5 EIM88607.1 - 4.7e-32 110.0 5.2 7.5e-32 109.4 5.2 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EIM88607.1 - 1.5e-05 25.1 0.1 4e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EIM88607.1 - 5.9e-05 23.2 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EIM88607.1 - 0.035 14.2 3.9 0.58 10.3 0.0 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DMAP1 PF05499.12 EIM88607.1 - 0.081 12.8 0.6 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF498 PF04430.14 EIM88608.1 - 8.1e-35 119.2 0.0 1e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DegV PF02645.16 EIM88608.1 - 0.27 10.5 0.0 0.36 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 CHCH PF06747.13 EIM88610.1 - 6.8e-07 29.3 10.4 2.5e-06 27.5 4.2 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 EIM88610.1 - 0.00026 20.9 9.2 0.069 13.2 3.5 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EIM88610.1 - 1 9.7 10.2 9.6 6.6 0.6 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DB PF01682.19 EIM88610.1 - 1.4 9.2 8.1 28 5.1 8.2 2.1 1 1 0 1 1 1 0 DB module Cmc1 PF08583.10 EIM88610.1 - 3 7.9 13.8 2 8.5 4.7 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 EIM88610.1 - 3.5 7.9 12.9 0.87 9.9 6.2 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb GCK PF07802.11 EIM88610.1 - 5.8 7.4 10.7 0.79 10.2 2.7 2.2 1 1 1 2 2 2 0 GCK domain MWFE PF15879.5 EIM88611.1 - 9.5e-24 83.3 0.1 1.2e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit BPL_LplA_LipB PF03099.19 EIM88612.1 - 4e-07 30.0 0.0 8.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 EIM88612.1 - 2.2e-05 24.4 0.0 8.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus ANAPC4_WD40 PF12894.7 EIM88613.1 - 9.6e-07 29.0 0.0 0.18 12.1 0.0 3.9 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM88613.1 - 0.00022 21.9 4.5 4.1 8.4 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Mito_fiss_reg PF05308.11 EIM88615.1 - 0.018 15.1 0.5 0.024 14.7 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Abhydrolase_1 PF00561.20 EIM88616.1 - 2.4e-21 76.6 0.3 4.7e-13 49.4 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM88616.1 - 1.1e-16 62.2 0.9 1.1e-16 62.2 0.9 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM88616.1 - 7.4e-15 54.9 0.0 1.9e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EIM88616.1 - 4.3e-07 30.0 0.0 7.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 EIM88616.1 - 0.00021 21.1 0.1 0.82 9.4 0.0 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIM88616.1 - 0.0014 18.2 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EIM88616.1 - 0.0014 18.5 0.2 0.0023 17.8 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EIM88616.1 - 0.0045 16.6 0.2 1.3 8.6 0.3 3.0 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EIM88616.1 - 0.011 15.7 0.0 0.062 13.2 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 EIM88616.1 - 0.079 12.4 0.4 0.51 9.8 0.2 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S28 PF05577.12 EIM88616.1 - 0.24 10.2 0.2 0.36 9.6 0.2 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 MFS_1 PF07690.16 EIM88617.1 - 7.1e-30 104.1 24.3 1.7e-24 86.4 9.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EIM88617.1 - 0.0043 16.4 13.6 0.0093 15.3 4.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 EIM88617.1 - 0.77 9.4 8.7 8.9 5.9 2.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) MgtC PF02308.16 EIM88617.1 - 6.1 7.2 11.2 0.071 13.5 1.1 2.9 3 1 0 3 3 3 0 MgtC family UBA_4 PF14555.6 EIM88618.1 - 0.23 11.3 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain GRDP-like PF07173.12 EIM88619.1 - 2.1e-24 86.8 0.5 3.1e-18 66.8 0.0 3.3 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like DUF2318 PF10080.9 EIM88619.1 - 0.15 12.2 1.1 0.39 10.9 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) TackOD1 PF18551.1 EIM88619.1 - 0.15 11.7 0.4 0.26 10.9 0.4 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EIM88619.1 - 0.28 11.6 4.3 0.17 12.3 0.6 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Menin PF05053.13 EIM88621.1 - 0.24 9.7 10.5 0.31 9.4 10.5 1.1 1 0 0 1 1 1 0 Menin Metallophos PF00149.28 EIM88622.1 - 1.8e-09 38.4 7.9 3.7e-09 37.4 7.9 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM88622.1 - 3.3e-07 30.6 1.2 8.2e-06 26.1 1.2 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EIM88622.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily LNP1 PF15419.6 EIM88623.1 - 0.026 14.8 1.3 0.034 14.4 1.3 1.3 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 SUI1 PF01253.22 EIM88624.1 - 1.1e-22 80.4 0.2 2e-22 79.5 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 EIM88624.1 - 0.0048 16.9 0.8 0.01 15.8 0.7 1.5 2 0 0 2 2 2 1 Transposon-encoded protein TnpV YscO PF07321.12 EIM88624.1 - 0.0074 16.2 4.1 0.011 15.7 4.1 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO TPR_1 PF00515.28 EIM88626.1 - 6.1e-07 29.0 0.1 0.13 12.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM88626.1 - 3.3e-06 26.8 2.4 0.022 14.8 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 EIM88626.1 - 4.7e-05 23.2 0.0 0.00015 21.6 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 EIM88626.1 - 0.037 14.2 0.1 0.16 12.1 0.0 2.1 3 0 0 3 3 3 0 DnaJ domain TPR_14 PF13428.6 EIM88626.1 - 0.11 13.4 0.0 0.11 13.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM88626.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIM88626.1 - 1.9 9.2 5.9 1.7 9.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1g PF09334.11 EIM88627.1 - 1e-85 287.9 0.0 5.9e-85 285.4 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EIM88627.1 - 1.7e-17 62.9 0.1 3.9e-08 32.0 0.0 4.1 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EIM88627.1 - 5.1e-06 26.0 0.0 0.047 13.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EIM88627.1 - 0.0042 17.1 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA NPV_P10 PF05531.12 EIM88627.1 - 0.1 13.1 2.1 0.24 11.9 2.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DSPc PF00782.20 EIM88628.1 - 8.2e-32 109.8 0.0 1.1e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIM88628.1 - 0.00013 21.6 0.1 0.00019 21.1 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EIM88628.1 - 0.002 18.4 0.1 0.004 17.4 0.1 1.6 1 1 0 1 1 1 1 Rit1 DUSP-like domain Peptidase_M24 PF00557.24 EIM88629.1 - 1.6e-48 165.2 0.0 2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 p450 PF00067.22 EIM88631.1 - 4.3e-62 210.4 0.0 6.1e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GTP_cyclohydro2 PF00925.20 EIM88633.1 - 1e-59 200.8 0.0 1.7e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Vps5 PF09325.10 EIM88634.1 - 1.1e-14 54.6 3.3 1.5e-14 54.2 3.3 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EIM88634.1 - 4.3e-13 49.2 0.2 1.1e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 PX domain Tropomyosin PF00261.20 EIM88634.1 - 0.49 9.7 8.6 2.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Tropomyosin Peptidase_M24 PF00557.24 EIM88635.1 - 8.9e-10 38.6 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_hydro_43 PF04616.14 EIM88636.1 - 7.4e-41 140.3 0.2 9.1e-41 140.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Smg8_Smg9 PF10220.9 EIM88636.1 - 0.26 9.6 0.2 0.35 9.1 0.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 PI3_PI4_kinase PF00454.27 EIM88637.1 - 8.7e-56 189.5 0.0 2.4e-55 188.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EIM88637.1 - 3.4e-27 95.6 0.7 7.4e-27 94.5 0.7 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.13 EIM88637.1 - 3.1e-25 88.0 0.4 1.7e-24 85.7 0.4 2.4 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 EIM88637.1 - 1.3e-10 40.9 0.0 3.8e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 EIM88637.1 - 0.0049 16.8 0.2 0.086 12.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) YEATS PF03366.16 EIM88638.1 - 1.5e-36 124.2 0.1 2.4e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 YEATS family Dyp_perox PF04261.12 EIM88639.1 - 8.1e-06 25.0 0.0 7.3e-05 21.9 0.0 2.5 3 1 0 3 3 3 1 Dyp-type peroxidase family FAD_binding_6 PF00970.24 EIM88640.1 - 3.8e-10 40.0 0.0 8.4e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EIM88640.1 - 8e-07 29.7 0.0 1.9e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EIM88640.1 - 0.00033 20.8 0.0 0.018 15.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Retrotran_gag_2 PF14223.6 EIM88644.1 - 1.4e-20 73.3 0.8 1.8e-20 73.0 0.8 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EIM88644.1 - 0.00064 19.5 0.1 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type His_Phos_1 PF00300.22 EIM88644.1 - 0.098 12.3 0.1 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) OrsD PF12013.8 EIM88646.1 - 0.055 13.9 0.1 0.055 13.9 0.1 2.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Plavaka PF18759.1 EIM88648.1 - 8.5e-14 51.5 0.1 1.6e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase Glycos_transf_N PF04413.16 EIM88648.1 - 0.056 13.1 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) AAA_16 PF13191.6 EIM88649.1 - 0.0003 21.2 0.0 0.00058 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RHSP PF07999.11 EIM88649.1 - 0.001 18.0 0.1 0.042 12.6 0.1 2.1 1 1 0 1 1 1 1 Retrotransposon hot spot protein AAA_22 PF13401.6 EIM88649.1 - 0.031 14.6 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EIM88649.1 - 0.036 13.2 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 EIM88649.1 - 0.077 12.6 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EIM88649.1 - 0.082 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EIM88649.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EIM88649.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EIM88649.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 EIM88649.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 EIM88649.1 - 0.15 11.3 0.0 0.45 9.7 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 EIM88649.1 - 0.19 12.0 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EIM88650.1 - 6e-66 222.5 0.0 7.1e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88650.1 - 1.6e-31 109.6 0.0 7.7e-31 107.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EIM88650.1 - 5.5e-05 22.6 0.3 8.9e-05 21.9 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIM88650.1 - 0.00066 18.7 0.1 0.00095 18.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIM88650.1 - 0.0045 16.3 0.1 0.01 15.2 0.1 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EIM88650.1 - 0.013 15.5 1.0 2.8 7.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EIM88650.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-CCCH_4 PF18044.1 EIM88651.1 - 4.5e-08 32.7 9.2 5.1e-05 23.0 0.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EIM88651.1 - 5.6e-06 26.2 12.7 3.6e-05 23.6 1.7 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EIM88651.1 - 2.2e-05 24.2 8.0 9.4e-05 22.2 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EIM88651.1 - 4.7e-05 24.0 5.0 0.0014 19.3 0.4 3.4 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 EIM88651.1 - 0.013 15.7 1.3 0.013 15.7 1.3 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Zip PF02535.22 EIM88651.1 - 0.07 12.3 2.2 0.17 11.1 2.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 EIM88651.1 - 0.62 10.1 2.9 1.7 8.6 2.9 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 EIM88651.1 - 3 6.3 8.6 7 5.1 8.6 1.5 1 0 0 1 1 1 0 Macoilin family REC114-like PF15165.6 EIM88651.1 - 5.4 6.7 7.9 10 5.9 7.9 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like zf-CCCH_2 PF14608.6 EIM88651.1 - 9.5 6.9 12.0 0.3 11.6 2.3 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger WD40 PF00400.32 EIM88652.1 - 2.5e-41 138.9 1.4 2.9e-06 27.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88652.1 - 6.8e-18 64.8 0.1 6.5e-05 23.1 0.0 5.2 3 3 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM88652.1 - 3.4e-07 29.6 0.0 2.7 6.9 0.0 4.3 4 1 0 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EIM88652.1 - 0.0003 19.6 0.0 0.43 9.2 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EIM88652.1 - 0.003 16.2 0.8 0.21 10.1 0.1 3.1 2 1 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 EIM88652.1 - 0.011 15.7 3.0 3.8 7.6 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EIM88652.1 - 0.051 12.6 0.1 5.4 6.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) VID27 PF08553.10 EIM88652.1 - 0.18 10.8 0.0 0.72 8.8 0.0 1.9 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain OTT_1508_deam PF14441.6 EIM88653.1 - 4.3e-05 23.4 1.0 9.8e-05 22.3 1.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase AMP-binding PF00501.28 EIM88654.1 - 1.2e-72 244.9 0.0 3.1e-72 243.5 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EIM88654.1 - 1.3e-71 241.7 0.0 3.1e-29 102.0 0.0 4.2 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EIM88654.1 - 2e-20 72.9 4.5 3.6e-08 33.7 0.1 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EIM88654.1 - 0.027 15.4 0.1 0.13 13.2 0.1 2.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 EIM88655.1 - 9.7e-52 175.8 0.0 1.2e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIM88655.1 - 3.4e-31 109.0 0.2 3.9e-29 102.2 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PSP PF04046.16 EIM88657.1 - 0.028 14.3 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 PSP Pyr_redox_2 PF07992.14 EIM88658.1 - 1.2e-30 106.7 0.2 2.6e-27 95.8 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM88658.1 - 3e-14 53.3 0.2 1.2e-10 41.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM88658.1 - 1.8e-07 30.7 0.2 4.3e-06 26.2 0.2 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM88658.1 - 3.1e-06 27.0 1.0 0.14 11.7 0.2 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EIM88658.1 - 2.1e-05 23.8 0.1 0.00041 19.6 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EIM88658.1 - 0.00011 22.3 0.1 2.5 8.1 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EIM88658.1 - 0.00015 20.8 0.3 0.44 9.3 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase TrkA_N PF02254.18 EIM88658.1 - 0.0022 18.2 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_7 PF13241.6 EIM88658.1 - 0.0031 17.9 0.6 0.37 11.2 0.1 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EIM88658.1 - 0.015 15.6 0.1 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain SIS PF01380.22 EIM88658.1 - 0.022 14.6 0.2 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 SIS domain Lycopene_cycl PF05834.12 EIM88658.1 - 0.084 11.9 1.1 6.7 5.6 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 EIM88658.1 - 0.094 11.4 0.0 4.3 5.9 0.0 2.5 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 EIM88658.1 - 0.1 12.8 0.2 7 7.0 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 EIM88658.1 - 0.11 12.1 0.0 1.5 8.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1188) K_oxygenase PF13434.6 EIM88659.1 - 1.7e-82 277.3 0.0 6.1e-82 275.5 0.0 1.8 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EIM88659.1 - 0.0011 19.0 0.1 0.22 11.5 0.0 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EIM88659.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Acetyltransf_8 PF13523.6 EIM88660.1 - 2.6e-27 95.3 0.2 1.1e-26 93.2 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EIM88661.1 - 1.5e-12 47.1 53.5 3.7e-10 39.3 35.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF5385 PF17359.2 EIM88661.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) MFS_1 PF07690.16 EIM88663.1 - 2.5e-08 33.3 45.1 1.2e-07 31.0 21.7 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily CBP_BcsG PF11658.8 EIM88666.1 - 0.075 11.4 0.0 0.089 11.2 0.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Myb_DNA-bind_3 PF12776.7 EIM88667.1 - 1.4e-06 29.1 0.0 2.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EIM88667.1 - 0.004 17.5 0.1 0.052 13.9 0.0 2.6 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Sigma70_ner PF04546.13 EIM88667.1 - 0.19 11.6 4.2 0.45 10.4 4.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 EIM88667.1 - 0.26 10.6 9.3 0.52 9.6 9.3 1.4 1 1 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 EIM88667.1 - 0.54 10.2 4.9 0.3 11.1 0.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 EIM88667.1 - 4.9 7.6 17.6 9.9 6.6 17.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EIM88667.1 - 5.8 7.2 11.8 16 5.8 11.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 EIM88667.1 - 6 4.8 13.3 9.1 4.2 13.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 EIM88669.1 - 2.2e-09 37.1 0.0 7.7e-08 32.0 0.0 2.4 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88669.1 - 0.0009 18.6 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC_membrane PF00664.23 EIM88670.1 - 1.2e-64 218.7 25.0 4.1e-37 128.3 12.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM88670.1 - 1.1e-49 168.5 0.0 1.9e-26 93.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM88670.1 - 4.4e-10 39.4 0.7 0.004 16.6 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIM88670.1 - 0.00018 21.2 1.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIM88670.1 - 0.00051 20.1 0.6 1 9.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM88670.1 - 0.00056 20.3 0.6 0.48 10.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EIM88670.1 - 0.003 16.9 0.4 0.44 9.9 0.2 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.6 EIM88670.1 - 0.0049 16.7 0.6 0.59 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system TrwB_AAD_bind PF10412.9 EIM88670.1 - 0.0083 15.1 0.9 2.5 6.9 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 EIM88670.1 - 0.014 15.9 6.1 0.44 11.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EIM88670.1 - 0.022 14.4 0.1 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EIM88670.1 - 0.025 14.6 0.7 8 6.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EIM88670.1 - 0.026 14.0 0.9 5.2 6.5 0.2 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EIM88670.1 - 0.027 14.2 2.6 8.3 6.1 0.2 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EIM88670.1 - 0.038 13.9 2.2 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase PspB PF06667.12 EIM88670.1 - 0.045 13.8 0.4 0.16 12.1 0.4 1.9 1 0 0 1 1 1 0 Phage shock protein B AAA_22 PF13401.6 EIM88670.1 - 0.052 13.8 1.9 13 6.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EIM88670.1 - 0.071 12.7 1.1 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EIM88670.1 - 0.092 12.8 3.8 0.16 12.0 0.6 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 EIM88670.1 - 0.11 12.4 0.4 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EIM88670.1 - 0.15 11.8 1.9 17 5.1 0.3 2.8 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EIM88670.1 - 0.18 11.1 0.6 12 5.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EIM88670.1 - 0.23 10.6 0.9 2.7 7.1 0.5 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EIM88670.1 - 3.8 7.7 4.3 19 5.4 0.2 2.8 3 0 0 3 3 3 0 AAA domain ToxB_N PF18224.1 EIM88672.1 - 0.028 14.3 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 ToxB N-terminal domain Aldedh PF00171.22 EIM88674.1 - 1.7e-142 475.2 0.0 2.1e-142 474.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM88674.1 - 0.063 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) p450 PF00067.22 EIM88675.1 - 5.3e-58 196.9 0.0 6.1e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM88677.1 - 2.5e-10 39.7 0.0 2.9e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2 PF00152.20 EIM88678.1 - 1.1e-81 274.4 0.0 1.3e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIM88678.1 - 2.4e-14 53.1 0.0 5.1e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EIM88678.1 - 0.00017 21.7 0.0 0.00059 20.0 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Cytochrom_B561 PF03188.16 EIM88680.1 - 1.8e-12 47.6 10.5 2.2e-12 47.3 10.5 1.1 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF5079 PF16882.5 EIM88680.1 - 0.29 11.0 3.2 0.33 10.8 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) DUF4079 PF13301.6 EIM88680.1 - 0.3 11.2 10.6 1.8 8.7 2.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 EIM88680.1 - 0.32 10.8 7.3 0.12 12.2 3.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4181 PF13789.6 EIM88680.1 - 1 9.7 6.1 0.16 12.2 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) DUF420 PF04238.12 EIM88680.1 - 3.4 7.9 11.1 1.2 9.4 5.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Kinesin PF00225.23 EIM88681.1 - 1.7e-92 309.9 0.0 2.3e-92 309.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIM88681.1 - 7.4e-20 71.4 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding TPR_2 PF07719.17 EIM88681.1 - 0.022 14.9 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 EIM88682.1 - 0.095 12.5 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribo_biogen_C PF04034.13 EIM88684.1 - 1.1e-51 173.8 0.0 1.5e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EIM88684.1 - 1.3e-14 53.7 0.0 2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Baculo_gp41 PF04700.12 EIM88685.1 - 0.00027 20.8 0.7 0.13 12.0 0.0 2.4 3 0 0 3 3 3 2 Structural glycoprotein p40/gp41 conserved region EptA_B_N PF08019.12 EIM88685.1 - 0.013 15.4 0.2 4.3 7.2 0.0 2.9 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Abhydrolase_3 PF07859.13 EIM88685.1 - 0.092 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PIF1 PF05970.14 EIM88690.1 - 0.00022 20.6 0.1 0.29 10.3 0.0 2.3 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EIM88690.1 - 0.019 14.7 0.0 0.45 10.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain SH3_13 PF18335.1 EIM88690.1 - 0.037 13.8 0.1 0.092 12.6 0.1 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Peptidase_C14 PF00656.22 EIM88691.1 - 0.012 15.6 0.0 0.05 13.5 0.0 1.8 1 1 0 2 2 2 0 Caspase domain BCDHK_Adom3 PF10436.9 EIM88692.1 - 8.7e-66 220.7 0.0 1.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EIM88692.1 - 2.1e-13 50.8 0.0 5.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EIM88692.1 - 0.0048 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.16 EIM88693.1 - 2.9e-21 75.8 44.3 2.9e-21 75.8 44.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM88693.1 - 0.12 11.2 32.8 0.085 11.7 8.7 2.6 3 0 0 3 3 3 0 Sugar (and other) transporter Ricin_B_lectin PF00652.22 EIM88694.1 - 1.2e-12 48.1 0.1 8.1e-05 22.9 0.0 3.5 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIM88694.1 - 2e-08 34.9 0.7 0.0082 16.9 0.1 3.9 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like FIST_C PF10442.9 EIM88694.1 - 0.0022 18.0 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 2 FIST C domain Med3 PF11593.8 EIM88694.1 - 4 6.5 11.1 7.5 5.6 11.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAP1 PF07218.11 EIM88694.1 - 8.5 4.5 6.6 11 4.1 6.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HNH_2 PF13391.6 EIM88696.1 - 1.4e-07 31.5 0.0 5e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease Tombus_movement PF05318.12 EIM88696.1 - 0.11 13.3 0.2 0.26 12.2 0.2 1.6 1 0 0 1 1 1 0 Tombusvirus movement protein PAS_9 PF13426.7 EIM88698.1 - 9.1e-25 86.9 0.0 4e-16 59.2 0.0 4.1 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 EIM88698.1 - 2.3e-14 53.3 0.0 9.4e-07 28.8 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 EIM88698.1 - 3.2e-10 40.2 0.0 0.00016 21.9 0.0 4.7 5 0 0 5 5 5 2 PAS fold PAS_4 PF08448.10 EIM88698.1 - 1.1e-09 38.5 0.0 2.5e-05 24.5 0.0 3.7 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 EIM88698.1 - 9.9e-05 22.3 0.0 0.84 9.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 EIM88698.1 - 0.0073 16.4 0.0 0.05 13.7 0.0 2.2 2 0 0 2 2 2 1 PAS domain Ribosomal_L16 PF00252.18 EIM88699.1 - 5e-45 152.7 0.0 6.2e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.11 EIM88699.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein WD40 PF00400.32 EIM88700.1 - 1.3e-57 190.4 18.1 4.2e-08 33.7 0.9 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EIM88700.1 - 2.7e-30 104.5 5.5 4.2e-30 103.9 5.5 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EIM88700.1 - 4e-21 75.1 0.5 3.6e-05 24.0 0.0 6.4 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIM88700.1 - 4.5e-12 45.9 0.0 0.0078 15.6 0.0 4.8 3 2 2 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 EIM88700.1 - 2.3e-09 36.7 0.3 0.42 9.5 0.0 5.8 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EIM88700.1 - 4.8e-05 23.3 0.0 0.025 14.5 0.0 3.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EIM88700.1 - 0.00029 20.7 0.0 15 5.7 0.0 5.5 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EIM88700.1 - 0.00063 18.4 0.9 0.081 11.4 0.1 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.6 EIM88700.1 - 0.0014 18.0 0.2 6.7 5.9 0.0 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Golgin_A5 PF09787.9 EIM88700.1 - 0.0034 16.9 2.2 0.0034 16.9 2.2 1.6 2 0 0 2 2 1 1 Golgin subfamily A member 5 Nup160 PF11715.8 EIM88700.1 - 0.0091 14.7 0.1 1.7 7.2 0.0 3.0 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Gmad1 PF10647.9 EIM88700.1 - 0.013 15.3 0.3 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PSII_BNR PF14870.6 EIM88700.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 DUF3450 PF11932.8 EIM88700.1 - 0.02 14.2 0.6 0.034 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 EIM88700.1 - 0.045 13.0 0.2 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 EIM88700.1 - 0.081 11.8 2.5 0.12 11.2 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EIM88700.1 - 1.2 9.2 10.2 0.023 14.7 3.4 1.6 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Proteasome_A_N PF10584.9 EIM88700.1 - 1.2 8.9 3.8 1.4e+02 2.2 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature ADH_N PF08240.12 EIM88701.1 - 1.9e-23 82.4 0.0 3.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM88701.1 - 2.8e-05 24.1 0.0 6.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM88701.1 - 0.00058 20.9 0.0 0.0022 19.0 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EIM88702.1 - 2.1e-70 237.7 0.0 2.6e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EIM88702.1 - 9.9e-05 22.8 0.2 0.049 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM88702.1 - 0.00012 21.5 0.8 0.012 14.9 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM88702.1 - 0.00024 21.2 0.1 0.00063 19.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM88702.1 - 0.00036 19.9 0.1 0.00058 19.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EIM88702.1 - 0.00083 18.3 0.2 0.0036 16.2 0.1 1.8 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EIM88702.1 - 0.0014 17.8 0.2 0.0046 16.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EIM88702.1 - 0.0022 17.3 0.1 0.0044 16.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM88702.1 - 0.0044 15.8 1.0 0.0066 15.2 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EIM88702.1 - 0.01 15.2 0.6 0.014 14.8 0.6 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 EIM88702.1 - 0.014 15.0 0.7 0.023 14.3 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM88702.1 - 0.046 12.8 0.2 0.066 12.2 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EIM88702.1 - 0.051 12.6 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Peroxidase_2 PF01328.17 EIM88703.1 - 1.5e-53 182.2 0.0 1.8e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 HMG_CoA_synt_N PF01154.17 EIM88704.1 - 5.2e-83 277.2 0.2 1e-82 276.2 0.2 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EIM88704.1 - 2.6e-79 266.8 0.2 6.2e-79 265.5 0.2 1.6 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 EIM88704.1 - 0.032 14.1 0.1 0.094 12.6 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EIM88704.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Terpene_synth_C PF03936.16 EIM88705.1 - 7.7e-05 22.2 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RVP_2 PF08284.11 EIM88705.1 - 0.14 11.9 0.2 0.3 10.9 0.2 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease ER_lumen_recept PF00810.18 EIM88706.1 - 6.6e-12 46.5 0.1 2.3e-11 44.7 0.0 1.9 1 1 1 2 2 2 1 ER lumen protein retaining receptor HMG_CoA_synt_C PF08540.10 EIM88708.1 - 5.9e-86 288.6 0.1 2.1e-85 286.8 0.1 1.8 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EIM88708.1 - 3.8e-83 277.6 0.1 6.8e-83 276.8 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 EIM88708.1 - 0.041 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EIM88708.1 - 0.17 12.1 0.0 0.53 10.5 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal p450 PF00067.22 EIM88709.1 - 7.9e-65 219.4 0.0 2.3e-64 217.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EIM88710.1 - 1.1e-14 54.6 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM88710.1 - 8.4e-12 45.1 0.0 1.1e-05 25.3 0.0 2.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 EIM88710.1 - 4.8e-11 43.2 0.0 5.4e-10 39.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM88710.1 - 1.2e-10 41.9 0.0 2.8e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM88710.1 - 2.4e-08 34.6 0.0 6.3e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EIM88710.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 EIM88710.1 - 0.0019 17.7 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CheR PF01739.18 EIM88710.1 - 0.002 17.7 0.0 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 EIM88710.1 - 0.0032 16.8 0.0 0.016 14.6 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 EIM88710.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 EIM88710.1 - 0.0063 15.9 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EIM88710.1 - 0.017 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EIM88710.1 - 0.039 13.2 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain MTS PF05175.14 EIM88710.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EIM88710.1 - 0.21 11.3 0.0 0.54 10.0 0.0 1.8 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pyr_redox_3 PF13738.6 EIM88711.1 - 8.5e-24 84.3 0.0 3.7e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIM88711.1 - 4.4e-20 71.6 0.0 5.3e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM88711.1 - 2.4e-13 50.0 0.1 5e-08 32.5 0.1 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM88711.1 - 1.5e-11 44.0 0.0 1.9e-09 37.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EIM88711.1 - 3.1e-05 23.4 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 EIM88711.1 - 3.7e-05 23.8 0.1 0.056 13.5 0.0 2.5 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EIM88711.1 - 4.5e-05 22.3 0.8 0.0002 20.2 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EIM88711.1 - 9.7e-05 22.9 0.2 0.014 15.9 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM88711.1 - 0.00011 22.4 0.0 0.00036 20.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM88711.1 - 0.00038 19.7 0.1 0.0012 18.0 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EIM88711.1 - 0.0044 16.1 0.1 0.046 12.8 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EIM88711.1 - 0.0055 16.7 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EIM88711.1 - 0.0061 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EIM88711.1 - 0.015 15.6 0.0 0.053 13.8 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 EIM88711.1 - 0.024 13.9 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EIM88711.1 - 0.031 13.5 0.1 0.19 11.0 0.0 2.3 3 0 0 3 3 3 0 Thi4 family DAO PF01266.24 EIM88711.1 - 0.051 13.2 0.4 0.97 8.9 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EIM88711.1 - 0.056 12.8 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EIM88711.1 - 0.087 13.3 0.0 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 EIM88711.1 - 0.13 11.5 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Glu_dehyd_C PF16912.5 EIM88711.1 - 0.15 11.5 0.2 0.77 9.2 0.0 2.1 3 0 0 3 3 2 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 EIM88711.1 - 0.17 10.9 0.0 4.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Polysacc_deac_1 PF01522.21 EIM88713.1 - 4.3e-11 42.8 0.0 9.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase HD_3 PF13023.6 EIM88714.1 - 3.8e-43 147.3 0.9 4.8e-43 146.9 0.9 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EIM88714.1 - 3.7e-11 43.1 1.2 6.1e-11 42.4 1.2 1.4 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EIM88714.1 - 1.2e-05 25.5 0.5 2.3e-05 24.6 0.5 1.5 1 0 0 1 1 1 1 HD domain DUF1018 PF06252.12 EIM88714.1 - 0.069 14.1 0.1 0.12 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) FHA PF00498.26 EIM88715.1 - 4.2e-15 55.9 0.0 2.5e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 FHA domain DUF4407 PF14362.6 EIM88715.1 - 0.00088 18.7 15.4 0.036 13.4 1.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EIM88715.1 - 0.0066 16.5 15.6 0.17 12.0 1.8 3.6 2 1 0 3 3 3 2 Protein of unknown function (DUF1664) Yop-YscD_cpl PF16697.5 EIM88715.1 - 0.009 16.3 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Lipoprotein_7 PF01540.16 EIM88715.1 - 0.033 13.5 0.6 0.055 12.8 0.6 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein Phage_GP20 PF06810.11 EIM88715.1 - 0.038 13.8 5.1 0.75 9.6 0.1 2.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 NST1 PF13945.6 EIM88715.1 - 0.13 12.4 0.1 0.13 12.4 0.1 3.1 3 1 0 3 3 3 0 Salt tolerance down-regulator EHN PF06441.12 EIM88715.1 - 0.93 9.9 3.5 0.95 9.9 1.0 2.3 2 0 0 2 2 2 0 Epoxide hydrolase N terminus FAD-SLDH PF12318.8 EIM88715.1 - 0.98 9.5 3.6 0.48 10.5 0.6 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_13 PF13166.6 EIM88715.1 - 1.9 7.0 9.8 0.07 11.8 2.2 2.0 2 0 0 2 2 2 0 AAA domain Cu-oxidase PF00394.22 EIM88718.1 - 3.9e-44 150.6 0.7 2.2e-41 141.6 0.0 2.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM88718.1 - 1.2e-36 125.5 4.0 5.4e-34 116.9 0.0 3.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM88718.1 - 2.2e-36 124.5 0.7 2.5e-35 121.0 0.4 2.5 2 0 0 2 2 2 1 Multicopper oxidase p450 PF00067.22 EIM88719.1 - 2.6e-64 217.7 0.0 8e-64 216.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Sel1 PF08238.12 EIM88720.1 - 1e-15 57.8 17.8 6.8e-07 29.8 0.1 6.2 6 0 0 6 6 6 4 Sel1 repeat TPR_8 PF13181.6 EIM88720.1 - 0.00046 20.2 0.3 0.22 11.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM88720.1 - 0.013 15.6 0.1 0.013 15.6 0.1 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM88720.1 - 0.057 14.3 1.4 17 6.6 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIM88720.1 - 4.6 7.2 9.2 3.5 7.6 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3602 PF12223.8 EIM88721.1 - 9.5e-12 45.4 11.6 1.7e-05 25.3 4.3 3.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) adh_short PF00106.25 EIM88722.1 - 4.3e-27 94.8 0.0 2.3e-25 89.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM88722.1 - 2.1e-15 56.9 0.0 2.1e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM88722.1 - 2.4e-08 33.7 0.1 8.4e-08 32.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM88722.1 - 2e-06 27.8 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EIM88722.1 - 0.00028 20.4 0.1 0.00092 18.7 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM88722.1 - 0.092 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding BTB PF00651.31 EIM88724.1 - 7.4e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-RRPl_C4 PF17026.5 EIM88724.1 - 0.046 13.8 0.6 0.11 12.7 0.6 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type BTB PF00651.31 EIM88725.1 - 4.7e-07 30.0 0.1 8.3e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain HCNGP PF07818.13 EIM88726.1 - 2.1e-22 79.6 3.4 4.8e-21 75.2 3.4 2.4 1 1 0 1 1 1 1 HCNGP-like protein PutA_N PF18083.1 EIM88726.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Proline utilization A N-terminal domain CAP_N PF01213.19 EIM88726.1 - 7.4 6.0 10.9 0.52 9.7 5.3 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DnaJ PF00226.31 EIM88727.1 - 1.8e-19 69.6 0.2 1.4e-16 60.3 0.0 2.7 2 0 0 2 2 2 2 DnaJ domain V_ATPase_I PF01496.19 EIM88727.1 - 2 6.3 4.2 2.4 6.0 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family p450 PF00067.22 EIM88728.1 - 6.4e-67 226.3 0.0 7.2e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I10 PF12559.8 EIM88728.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine endopeptidase inhibitors Amidase PF01425.21 EIM88729.1 - 2.5e-98 330.0 0.0 2.9e-98 329.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Sel_put PF04328.13 EIM88729.1 - 0.15 12.1 0.1 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Selenoprotein, putative AMP-binding PF00501.28 EIM88730.1 - 1.6e-67 228.0 0.0 2.2e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme MR_MLE_C PF13378.6 EIM88731.1 - 4.8e-48 163.6 0.2 7.2e-47 159.8 0.2 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EIM88731.1 - 9.1e-07 29.1 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF3025 PF11227.8 EIM88731.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) MAAL_C PF07476.11 EIM88731.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus FAD_binding_3 PF01494.19 EIM88732.1 - 1.6e-17 63.8 0.0 5e-16 58.9 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM88732.1 - 6.5e-07 29.5 0.8 2.8e-05 24.2 1.4 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM88732.1 - 0.00078 19.1 0.3 0.0012 18.5 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIM88732.1 - 0.0025 16.7 1.9 0.0033 16.4 0.5 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EIM88732.1 - 0.0053 16.0 0.8 0.17 11.1 1.2 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM88732.1 - 0.011 15.0 0.7 0.022 14.0 0.7 1.4 1 0 0 1 1 1 0 Thi4 family MCR_D PF02505.14 EIM88732.1 - 0.22 11.4 0.0 1 9.2 0.0 1.9 1 1 1 2 2 2 0 Methyl-coenzyme M reductase operon protein D HI0933_like PF03486.14 EIM88732.1 - 0.28 9.9 0.8 3.3 6.3 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EIM88732.1 - 2.3 7.2 3.5 3.9 6.4 3.5 1.3 1 0 0 1 1 1 0 FAD binding domain APG6_N PF17675.1 EIM88733.1 - 0.015 15.9 2.9 0.015 15.9 2.9 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 EIM88733.1 - 0.1 12.4 1.9 0.19 11.6 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 EIM88733.1 - 0.1 12.1 5.8 0.16 11.4 5.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 EIM88733.1 - 0.23 10.3 4.8 0.35 9.7 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FSAP_sig_propep PF03032.15 EIM88733.1 - 0.56 10.3 2.7 2 8.5 2.7 1.9 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide LRRFIP PF09738.9 EIM88733.1 - 0.87 9.0 15.9 0.46 9.9 12.5 2.1 1 1 0 1 1 1 0 LRRFIP family Fez1 PF06818.15 EIM88733.1 - 3.7 8.0 9.0 0.87 10.0 5.3 1.7 1 1 1 2 2 2 0 Fez1 JIP_LZII PF16471.5 EIM88733.1 - 5.4 7.3 8.8 1.6 9.0 2.1 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Zn_Tnp_IS1595 PF12760.7 EIM88734.1 - 0.004 17.1 1.7 0.011 15.8 1.7 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain PBP1_TM PF14812.6 EIM88734.1 - 0.081 13.3 3.3 0.32 11.4 3.3 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 EIM88734.1 - 0.095 12.8 2.0 0.15 12.2 2.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein zf-C2H2_4 PF13894.6 EIM88734.1 - 0.13 13.1 3.3 2.7 9.1 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FAD_binding_3 PF01494.19 EIM88735.1 - 2.4e-18 66.5 0.2 4.1e-08 32.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM88735.1 - 0.00021 21.5 0.2 0.00056 20.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM88735.1 - 0.005 16.5 0.4 0.0082 15.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM88735.1 - 0.0062 15.8 1.0 0.03 13.6 0.7 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.31 EIM88736.1 - 0.00029 21.0 0.0 0.0005 20.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain LSM PF01423.22 EIM88738.1 - 2.9e-19 68.5 0.8 3.6e-19 68.2 0.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIM88738.1 - 0.0049 17.0 0.1 0.0065 16.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 EIM88738.1 - 0.028 14.3 0.2 0.047 13.6 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 EIM88738.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BTB PF00651.31 EIM88739.1 - 1.7e-09 37.9 0.0 2.2e-08 34.3 0.0 2.6 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.25 EIM88739.1 - 1e-07 31.8 0.5 3.9e-06 26.8 0.3 2.5 2 0 0 2 2 2 1 CAP-Gly domain WD40 PF00400.32 EIM88740.1 - 1.5e-39 133.3 21.5 5.4e-07 30.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88740.1 - 6.8e-15 55.1 0.7 0.002 18.4 0.2 4.7 3 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM88740.1 - 2.1e-09 36.8 1.0 0.011 14.7 0.0 5.3 3 1 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM88740.1 - 3.7e-06 26.5 0.1 0.25 10.7 0.0 3.4 3 1 0 3 3 3 2 WD40-like domain Nucleoporin_N PF08801.11 EIM88740.1 - 0.00024 20.0 1.1 0.16 10.6 0.0 2.5 2 0 0 2 2 2 2 Nup133 N terminal like Kelch_6 PF13964.6 EIM88740.1 - 0.07 13.5 0.3 32 5.0 0.1 3.2 2 0 0 2 2 2 0 Kelch motif Proteasome_A_N PF10584.9 EIM88740.1 - 0.2 11.3 1.3 24 4.7 0.1 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature NAD_binding_4 PF07993.12 EIM88743.1 - 9.4e-33 113.5 0.0 1.8e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM88743.1 - 7.4e-28 97.3 0.0 3.5e-27 95.1 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM88743.1 - 5.3e-08 32.6 0.0 2.2e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM88743.1 - 0.00081 19.7 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GMC_oxred_N PF00732.19 EIM88744.1 - 3.4e-59 200.7 0.0 4.7e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM88744.1 - 4e-37 127.9 0.0 9.1e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM88744.1 - 4.3e-05 22.8 0.8 0.048 12.7 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM88744.1 - 0.00066 19.9 0.4 0.0019 18.4 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM88744.1 - 0.0025 16.9 0.3 0.0037 16.4 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EIM88744.1 - 0.019 14.3 2.0 1.5 8.0 0.4 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM88744.1 - 0.049 13.2 0.2 0.094 12.3 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM88744.1 - 0.076 11.7 0.4 0.41 9.3 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Cu-oxidase PF00394.22 EIM88745.1 - 3.1e-43 147.6 1.9 1.9e-38 132.1 0.1 2.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM88745.1 - 2.9e-37 127.3 1.1 3.1e-36 124.0 0.2 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM88745.1 - 2.2e-34 118.1 7.9 2.4e-33 114.8 0.8 3.5 3 1 0 3 3 3 2 Multicopper oxidase Aldo_ket_red PF00248.21 EIM88746.1 - 2.2e-23 82.9 0.0 2.9e-23 82.5 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_C13 PF01650.18 EIM88747.1 - 1e-44 153.0 0.1 1.3e-44 152.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 EIM88747.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute Melibiase_2 PF16499.5 EIM88748.1 - 2.3e-56 191.1 4.1 3.4e-56 190.5 4.1 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EIM88748.1 - 2.7e-14 53.0 0.5 1.2e-12 47.7 0.1 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EIM88748.1 - 3e-06 26.4 0.1 4.8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 EIM88748.1 - 0.023 12.5 0.0 0.033 12.0 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 FAD_binding_3 PF01494.19 EIM88749.1 - 1.7e-09 37.4 0.0 1.6e-08 34.2 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EIM88749.1 - 1.2e-07 31.8 0.3 3.7e-07 30.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM88749.1 - 3.4e-06 26.5 0.0 0.0085 15.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM88749.1 - 1.1e-05 25.2 1.0 0.00015 21.5 0.8 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM88749.1 - 1.2e-05 25.8 0.0 0.013 16.1 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EIM88749.1 - 2.2e-05 23.9 0.3 0.023 14.0 0.2 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EIM88749.1 - 2.9e-05 23.3 0.3 5e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EIM88749.1 - 0.014 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EIM88749.1 - 0.036 13.1 0.3 0.21 10.6 0.1 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EIM88749.1 - 0.037 12.7 0.0 0.06 12.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EIM88749.1 - 0.04 13.0 0.1 0.069 12.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 EIM88749.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain PALP PF00291.25 EIM88749.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_9 PF13454.6 EIM88749.1 - 0.074 13.0 0.2 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EIM88749.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM88749.1 - 0.22 10.7 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Hydrolase_4 PF12146.8 EIM88750.1 - 4.5e-14 52.3 0.0 9.5e-14 51.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM88750.1 - 5.6e-14 53.3 0.0 9.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM88750.1 - 4.9e-13 49.3 0.0 7.1e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM88750.1 - 0.00021 20.8 0.3 0.041 13.4 0.0 2.7 3 1 0 3 3 3 2 Prolyl oligopeptidase family BAAT_C PF08840.11 EIM88750.1 - 0.013 15.4 0.0 2.5 8.0 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EIM88750.1 - 0.03 13.9 0.0 9.1 5.8 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EIM88750.1 - 0.048 13.5 0.2 1.7 8.4 0.2 2.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EIM88750.1 - 0.051 13.7 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain zf-RVT PF13966.6 EIM88751.1 - 1.6e-07 31.9 1.1 1.1e-06 29.3 0.5 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase F-box-like PF12937.7 EIM88752.1 - 2.3e-09 37.0 0.3 5.3e-09 35.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM88752.1 - 0.018 14.9 2.1 0.041 13.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain p450 PF00067.22 EIM88754.1 - 7.1e-50 170.1 0.7 1.7e-26 93.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Bud13 PF09736.9 EIM88755.1 - 1.1e-53 181.5 14.3 1.1e-53 181.5 14.3 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Aminotran_1_2 PF00155.21 EIM88756.1 - 1e-26 94.0 0.0 1.1e-21 77.4 0.0 2.3 2 1 0 2 2 2 2 Aminotransferase class I and II RNA_pol_L_2 PF13656.6 EIM88759.1 - 6.2e-28 96.4 0.0 7.5e-28 96.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EIM88759.1 - 1.6e-07 30.7 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DSPc PF00782.20 EIM88761.1 - 1.7e-27 95.8 0.0 2.5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIM88761.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 EIM88761.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain CDKN3 PF05706.12 EIM88761.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 EIM88761.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 EIM88761.1 - 0.19 11.7 0.1 7.5 6.4 0.0 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family Abhydrolase_6 PF12697.7 EIM88763.1 - 1.2e-05 26.1 0.0 3.1e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.29 EIM88764.1 - 5.2e-31 107.8 0.1 3.9e-16 59.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM88764.1 - 5.7e-27 94.3 0.0 8.5e-26 90.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MFS_1 PF07690.16 EIM88767.1 - 3.3e-41 141.4 36.2 3.3e-41 141.4 36.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM88767.1 - 8.3e-14 51.3 3.9 8.3e-14 51.3 3.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 EIM88767.1 - 0.0016 16.9 3.8 0.0029 16.1 3.8 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Het-C PF07217.11 EIM88768.1 - 5.4e-214 711.9 0.0 6.7e-214 711.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C BTB PF00651.31 EIM88769.1 - 1.7e-07 31.4 0.1 5.3e-07 29.9 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain NADH_4Fe-4S PF10589.9 EIM88769.1 - 0.12 12.4 1.1 1.2 9.3 1.5 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region GTP_EFTU PF00009.27 EIM88770.1 - 2.5e-51 174.0 0.0 3.7e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EIM88770.1 - 9.8e-18 64.0 0.0 2.4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 EIM88770.1 - 8.7e-06 25.8 0.1 5.1e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EIM88770.1 - 3e-05 24.3 0.5 0.00011 22.5 0.5 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EIM88770.1 - 0.0051 16.3 0.3 1.4 8.3 0.0 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Sugar_tr PF00083.24 EIM88771.1 - 5.2e-88 295.9 18.6 6.3e-88 295.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM88771.1 - 5.6e-17 61.7 41.8 1.9e-10 40.2 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 EIM88772.1 - 5.3e-11 42.7 0.1 1.7e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Cu-oxidase PF00394.22 EIM88774.1 - 2.9e-49 167.2 0.4 2.8e-46 157.5 0.2 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM88774.1 - 5.1e-38 129.9 3.6 2.7e-34 117.8 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM88774.1 - 2.4e-36 124.3 5.4 1.3e-33 115.5 0.2 3.5 3 1 0 3 3 3 3 Multicopper oxidase BTB PF00651.31 EIM88776.1 - 1.5e-10 41.3 0.1 6.2e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EIM88777.1 - 7.7e-08 32.5 0.0 2.2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain PDEase_I PF00233.19 EIM88778.1 - 5.7e-58 196.4 0.4 1.4e-57 195.2 0.4 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EIM88778.1 - 0.022 15.0 0.3 0.091 13.0 0.1 2.0 1 1 1 2 2 2 0 HD domain BTB PF00651.31 EIM88779.1 - 1.8e-21 76.4 0.0 8.7e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain HalOD1 PF18545.1 EIM88779.1 - 0.0066 16.7 0.6 4 7.8 0.1 2.7 2 0 0 2 2 2 2 Halobacterial output domain 1 Methyltransf_16 PF10294.9 EIM88781.1 - 5.9e-10 39.2 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase RNA_pol_Rpb1_R PF05001.13 EIM88781.1 - 0.45 11.0 1.5 1 9.8 1.5 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat BTB PF00651.31 EIM88783.1 - 6.1e-12 45.7 0.0 1.4e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Sec23_trunk PF04811.15 EIM88784.1 - 2e-56 191.3 0.0 2.8e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EIM88784.1 - 3.9e-20 71.6 0.1 6.9e-20 70.8 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EIM88784.1 - 1.1e-13 51.0 2.2 2.2e-13 50.0 2.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EIM88784.1 - 1.5e-13 51.3 0.0 3.2e-11 43.8 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EIM88784.1 - 2.9e-05 23.9 0.0 6.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Mcp5_PH PF12814.7 EIM88785.1 - 6.7e-45 152.1 0.1 1.2e-44 151.4 0.1 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EIM88785.1 - 1.9e-05 25.1 0.0 3.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Fez1 PF06818.15 EIM88785.1 - 0.018 15.5 28.3 0.012 16.0 20.9 3.1 3 0 0 3 3 3 0 Fez1 Syntaxin_2 PF14523.6 EIM88785.1 - 0.097 13.0 12.7 0.62 10.5 10.9 2.9 2 1 0 2 2 2 0 Syntaxin-like protein DUF4763 PF15960.5 EIM88785.1 - 0.71 9.1 11.5 3.8 6.7 9.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) RsbU_N PF08673.10 EIM88785.1 - 1.5 8.9 3.0 0.62 10.2 0.3 1.7 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain NTF2 PF02136.20 EIM88786.1 - 1.4e-28 99.8 0.1 2.2e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EIM88786.1 - 6.7e-09 35.4 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM88786.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif BTB PF00651.31 EIM88787.1 - 2.6e-09 37.3 0.0 4.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3375 PF11855.8 EIM88787.1 - 0.13 11.1 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) BTB PF00651.31 EIM88788.1 - 3.3e-09 37.0 0.1 3.8e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain RRM_1 PF00076.22 EIM88788.1 - 7.7e-08 32.0 0.1 1.9e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM88788.1 - 0.033 14.0 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 EIM88788.1 - 0.12 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Mfa1 PF17445.2 EIM88788.1 - 0.16 12.0 1.1 0.36 10.9 1.1 1.5 1 0 0 1 1 1 0 Mating factor A1 BTB PF00651.31 EIM88789.1 - 1.2e-10 41.6 0.0 2.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 EIM88790.1 - 4e-65 219.8 0.0 4.8e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88790.1 - 3.2e-27 95.5 0.0 4.7e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM88790.1 - 6.3e-06 25.7 0.0 9.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM88790.1 - 0.00035 20.0 0.0 0.00066 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIM88790.1 - 0.00054 19.6 0.0 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EIM88790.1 - 0.0034 17.3 0.4 0.096 12.6 0.6 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM88790.1 - 0.03 13.3 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain ID PF18543.1 EIM88790.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Intracellular delivery domain AAA_lid_7 PF17867.1 EIM88791.1 - 0.031 14.5 0.1 0.08 13.2 0.1 1.7 1 0 0 1 1 1 0 Midasin AAA lid domain DUF3390 PF11870.8 EIM88791.1 - 0.13 12.6 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Rad52_Rad22 PF04098.15 EIM88794.1 - 5.8e-54 182.2 0.0 7.3e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MFS_1 PF07690.16 EIM88795.1 - 6.1e-29 101.1 26.8 1.2e-28 100.1 26.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 EIM88796.1 - 1.3e-53 182.0 0.0 2.2e-53 181.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM88796.1 - 9.8e-33 113.9 0.0 1.6e-31 109.9 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM88796.1 - 1.5e-23 82.7 0.1 2.7e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 EIM88797.1 - 4.9e-54 183.4 0.0 7.7e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM88797.1 - 7.9e-36 124.0 0.0 1.6e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM88797.1 - 1.5e-23 82.7 0.1 2.6e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PetM PF08041.11 EIM88798.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Cu-oxidase PF00394.22 EIM88799.1 - 2.3e-49 167.6 0.4 1e-46 158.9 0.3 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM88799.1 - 3.5e-38 130.4 2.2 6.8e-34 116.5 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM88799.1 - 2.1e-36 124.5 4.0 1.9e-34 118.2 0.2 3.3 3 1 0 3 3 3 2 Multicopper oxidase Sterol_MT_C PF08498.10 EIM88800.1 - 1.2e-27 95.9 1.0 2e-27 95.3 1.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EIM88800.1 - 9.5e-18 64.6 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM88800.1 - 1.1e-17 64.2 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM88800.1 - 1.4e-16 60.9 0.0 2.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EIM88800.1 - 2.6e-14 53.2 0.0 3.4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EIM88800.1 - 3e-12 47.2 0.1 9.1e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM88800.1 - 3.3e-10 40.1 0.0 4.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM88800.1 - 1.2e-07 31.3 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EIM88800.1 - 2.8e-05 24.0 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EIM88800.1 - 0.0008 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EIM88800.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 EIM88800.1 - 0.0027 16.9 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.16 EIM88800.1 - 0.0054 16.5 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 EIM88800.1 - 0.0079 17.2 0.0 0.026 15.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EIM88800.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 EIM88800.1 - 0.019 14.5 0.0 0.06 12.8 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 EIM88800.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 EIM88800.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 EIM88800.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Mob_Pre PF01076.19 EIM88800.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Plasmid recombination enzyme WD40 PF00400.32 EIM88802.1 - 2.7e-31 107.1 21.2 8.8e-05 23.2 0.1 10.9 10 1 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88802.1 - 4e-19 68.7 0.2 4.2e-08 33.4 0.0 5.6 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EIM88802.1 - 3.1e-05 24.3 7.2 0.35 11.4 0.1 6.6 7 0 0 7 7 7 1 PQQ-like domain Ge1_WD40 PF16529.5 EIM88802.1 - 3.6e-05 22.9 1.4 0.37 9.7 0.0 4.3 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EIM88802.1 - 8.6e-05 20.7 0.0 0.0056 14.8 0.0 2.3 3 0 0 3 3 3 2 IKI3 family GspH PF12019.8 EIM88802.1 - 0.0015 18.9 0.0 3.6 8.0 0.0 3.1 2 0 0 2 2 2 2 Type II transport protein GspH WD40_like PF17005.5 EIM88802.1 - 0.0026 17.1 0.0 2.6 7.3 0.0 3.1 3 1 0 3 3 3 2 WD40-like domain Nbas_N PF15492.6 EIM88802.1 - 0.003 16.9 0.6 5.2 6.3 0.0 3.7 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EIM88802.1 - 0.065 13.2 1.6 9.7 6.3 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EIM88802.1 - 0.085 11.5 0.1 0.24 10.0 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Mad3_BUB1_I PF08311.12 EIM88803.1 - 1.6e-35 121.8 0.2 2.5e-35 121.2 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 EIM88803.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein p450 PF00067.22 EIM88804.1 - 1.6e-62 211.8 0.0 2e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chordopox_A15 PF05846.12 EIM88805.1 - 0.011 16.0 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus A15 protein Phage_holin_2_4 PF16082.5 EIM88805.1 - 0.12 12.2 0.3 0.35 10.6 0.3 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Lig_chan PF00060.26 EIM88805.1 - 1.7 8.5 4.2 4.6 7.1 4.2 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel RRM_1 PF00076.22 EIM88806.1 - 2e-33 114.0 0.0 2.5e-16 59.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EIM88806.1 - 0.0049 17.0 0.6 5.4 7.3 0.0 2.7 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.13 EIM88806.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C2H2 PF00096.26 EIM88807.1 - 6.3e-05 23.2 2.1 0.00022 21.5 2.1 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM88807.1 - 0.09 13.7 0.9 0.32 11.9 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger RRM_1 PF00076.22 EIM88808.1 - 7.9e-12 44.8 0.0 1.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EIM88808.1 - 2.9e-09 37.3 2.0 7.5e-09 36.0 2.0 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 tRNA_anti-codon PF01336.25 EIM88809.1 - 4.9e-06 26.4 0.1 1.5e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 EIM88809.1 - 0.0002 20.4 0.2 0.39 9.6 0.0 2.4 2 0 0 2 2 2 2 Telomere regulation protein Stn1 Dioxygenase_C PF00775.21 EIM88812.1 - 7.2e-06 25.6 0.1 1.7e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase Abhydrolase_1 PF00561.20 EIM88817.1 - 8.2e-20 71.5 0.0 7.2e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM88817.1 - 1.9e-16 61.3 6.4 1.1e-14 55.6 6.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM88817.1 - 2.6e-09 36.7 0.0 2.4e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PH_17 PF18012.1 EIM88818.1 - 0.035 13.8 0.1 0.056 13.2 0.1 1.2 1 0 0 1 1 1 0 PH domain p450 PF00067.22 EIM88819.1 - 1e-59 202.5 0.0 2.4e-59 201.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ntox15 PF15604.6 EIM88819.1 - 0.033 14.3 0.1 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Novel toxin 15 UPF0029 PF01205.19 EIM88821.1 - 4.5e-26 91.2 0.0 5.8e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Sporozoite_P67 PF05642.11 EIM88824.1 - 0.057 11.5 2.2 0.036 12.2 0.4 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Sec2p PF06428.11 EIM88826.1 - 1.3e-13 50.7 12.7 1.3e-13 50.7 12.7 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p NUMOD1 PF07453.13 EIM88826.1 - 0.085 13.1 0.1 0.085 13.1 0.1 1.6 2 0 0 2 2 2 0 NUMOD1 domain Herpes_UL6 PF01763.16 EIM88826.1 - 0.66 8.4 5.9 0.21 10.0 2.6 1.7 1 1 0 2 2 2 0 Herpesvirus UL6 like DUF4200 PF13863.6 EIM88826.1 - 1.3 9.5 14.9 0.9 10.0 11.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.6 EIM88826.1 - 5.6 7.0 10.2 4.3 7.4 0.2 3.2 3 0 0 3 3 3 0 FlxA-like protein GvpL_GvpF PF06386.11 EIM88827.1 - 0.29 11.0 1.9 0.42 10.5 1.9 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ApoO PF09769.9 EIM88828.1 - 0.00025 21.0 0.3 2.3 8.2 0.0 4.2 2 2 3 5 5 5 2 Apolipoprotein O DUF2884 PF11101.8 EIM88828.1 - 0.31 10.5 4.5 0.38 10.2 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) Tox-PL-2 PF15643.6 EIM88828.1 - 0.43 10.7 4.8 9.1 6.5 0.3 2.5 2 0 0 2 2 2 0 Papain fold toxin 2 Sun2_CC2 PF18580.1 EIM88828.1 - 4.8 7.5 7.2 52 4.2 0.1 4.6 5 2 0 5 5 5 0 SUN2 coiled coil domain 2 p450 PF00067.22 EIM88830.1 - 1e-53 182.7 0.0 2.1e-53 181.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Dioxygenase_C PF00775.21 EIM88832.1 - 1.1e-43 148.8 0.0 1.4e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EIM88832.1 - 2.1e-27 94.8 0.0 3.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EIM88832.1 - 0.034 14.4 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain EI24 PF07264.11 EIM88834.1 - 1.1e-14 55.1 1.4 1.7e-14 54.4 1.4 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Colicin PF01024.19 EIM88834.1 - 0.17 11.7 1.8 0.41 10.5 1.8 1.5 1 0 0 1 1 1 0 Colicin pore forming domain DFP PF04127.15 EIM88836.1 - 6.7e-20 71.7 0.0 2e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Peptidase_M9_N PF08453.10 EIM88836.1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Egh16-like PF11327.8 EIM88837.1 - 1.1e-08 35.7 4.2 1.4e-08 35.3 4.2 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor ArsC PF03960.15 EIM88838.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 ArsC family RRM_1 PF00076.22 EIM88839.1 - 4.7e-22 77.6 0.0 2e-10 40.3 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RdRP PF05183.12 EIM88841.1 - 1.5e-147 492.8 0.0 2e-147 492.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase 5-FTHF_cyc-lig PF01812.20 EIM88842.1 - 6e-40 137.1 0.0 7e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PIG-P PF08510.12 EIM88843.1 - 5.4e-32 110.3 0.8 6.5e-32 110.0 0.8 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EIM88843.1 - 0.0038 17.5 8.6 0.011 16.1 8.6 1.6 1 1 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-H2C2_2 PF13465.6 EIM88844.1 - 1.6e-06 28.2 10.3 0.00011 22.4 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EIM88844.1 - 1.4e-05 25.3 15.7 0.00039 20.7 0.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM88844.1 - 0.00043 20.9 6.8 0.44 11.5 2.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM88844.1 - 0.23 11.8 1.8 2.9 8.3 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM88844.1 - 0.24 11.8 1.8 3.7 8.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type XPG_N PF00752.17 EIM88845.1 - 1.8e-25 89.4 0.0 4.8e-25 88.0 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EIM88845.1 - 5.2e-23 81.2 0.0 9.6e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EIM88845.1 - 9.1e-06 26.2 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 EIM88845.1 - 1.3e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 EIM88845.1 - 0.0047 17.0 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM88845.1 - 0.008 16.0 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM88845.1 - 0.038 14.3 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.9 EIM88845.1 - 0.054 13.2 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain HemY_N PF07219.13 EIM88845.1 - 0.058 13.6 0.2 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 HemY protein N-terminus TPR_14 PF13428.6 EIM88845.1 - 0.13 13.1 0.3 0.88 10.6 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.21 EIM88846.1 - 4.5e-41 140.3 6.1 7.3e-41 139.6 6.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EIM88846.1 - 0.0059 17.1 14.2 0.0059 17.1 14.2 1.8 2 0 0 2 2 2 1 Chitin recognition protein MutS_V PF00488.21 EIM88849.1 - 2.7e-62 210.2 0.2 5.7e-62 209.1 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIM88849.1 - 1.7e-38 132.8 0.7 4.3e-38 131.5 0.7 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EIM88849.1 - 1.5e-33 115.4 0.1 3.2e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EIM88849.1 - 6.1e-09 36.3 0.0 3.4e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EIM88849.1 - 3.7e-06 27.2 0.1 1.1e-05 25.7 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV CCDC-167 PF15188.6 EIM88849.1 - 7.3 7.0 7.2 1.6 9.1 1.7 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 MFS_1 PF07690.16 EIM88851.1 - 1.1e-23 83.7 34.9 7.2e-19 67.9 12.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM88851.1 - 0.002 17.0 9.2 0.002 17.0 9.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter CENP-B_dimeris PF09026.10 EIM88851.1 - 0.21 12.0 13.1 0.44 11.0 13.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MFS_1_like PF12832.7 EIM88851.1 - 0.25 10.2 17.8 0.26 10.1 0.4 3.1 2 1 1 3 3 3 0 MFS_1 like family Nop14 PF04147.12 EIM88851.1 - 1.7 6.8 4.1 2.4 6.3 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 EIM88851.1 - 7 4.6 21.1 0.0034 15.6 8.2 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen F-box PF00646.33 EIM88852.1 - 0.13 12.2 0.6 0.32 10.9 0.6 1.7 1 0 0 1 1 1 0 F-box domain DUF667 PF05018.13 EIM88854.1 - 3.8e-20 72.4 0.0 1.6e-09 37.7 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF667) HAD_2 PF13419.6 EIM88855.1 - 2.1e-06 27.9 0.0 9.1e-06 25.9 0.0 1.9 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM88855.1 - 0.0097 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EIM88855.1 - 0.022 15.1 0.0 0.055 13.8 0.0 1.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EIM88855.1 - 0.037 13.9 0.5 0.81 9.5 0.5 2.3 1 1 0 1 1 1 0 Acid Phosphatase DUF2608 PF11019.8 EIM88855.1 - 0.17 11.4 0.0 0.54 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Methyltransf_16 PF10294.9 EIM88856.1 - 1e-12 48.2 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EIM88856.1 - 0.12 13.1 0.0 0.53 11.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF4510 PF14971.6 EIM88858.1 - 0.003 17.9 0.0 0.0037 17.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4510) RRM_1 PF00076.22 EIM88859.1 - 2.1e-31 107.6 0.0 8e-16 57.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head PF16208.5 EIM88859.1 - 4.6 7.4 26.0 9.6 6.3 26.0 1.5 1 0 0 1 1 1 0 Keratin type II head F-box-like PF12937.7 EIM88860.1 - 1.4e-12 47.3 1.4 3.8e-12 45.9 1.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM88860.1 - 0.41 10.6 4.0 9.6 6.2 1.4 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EIM88861.1 - 6.5e-08 32.3 0.2 2.1e-07 30.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM88861.1 - 0.63 10.5 8.2 15 6.1 0.0 5.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM88861.1 - 1.2 8.9 9.4 29 4.5 0.0 5.0 5 0 0 5 5 5 0 Leucine rich repeat F-box PF00646.33 EIM88861.1 - 4.9 7.2 7.8 9 6.3 1.1 3.4 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EIM88862.1 - 1.2e-08 34.7 0.4 3.3e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM88862.1 - 0.02 15.3 0.0 30 5.2 0.0 3.8 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Metallophos PF00149.28 EIM88863.1 - 3.3e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIM88863.1 - 2.9e-21 75.6 0.4 6e-21 74.6 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 EIM88864.1 - 9.4e-42 140.2 19.9 2.1e-09 37.8 0.1 11.5 12 0 0 12 12 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88864.1 - 2e-24 85.7 0.1 0.00027 21.2 0.0 9.8 3 2 7 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EIM88864.1 - 4e-18 65.7 0.0 6.5e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EIM88864.1 - 5.4e-07 28.9 5.8 2 7.3 0.0 6.6 4 3 1 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EIM88864.1 - 3.5e-05 23.8 0.6 0.4 10.5 0.0 5.0 2 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EIM88864.1 - 6.4e-05 21.8 2.4 0.47 9.0 0.3 4.4 2 1 0 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EIM88864.1 - 0.0012 18.3 0.0 0.64 9.3 0.0 3.9 3 1 0 4 4 4 1 WD40-like domain Cytochrom_D1 PF02239.16 EIM88864.1 - 0.0013 17.3 0.2 1.2 7.6 0.0 3.5 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EIM88864.1 - 0.013 14.3 0.1 1.8 7.2 0.1 3.9 4 1 0 4 4 4 0 Nup133 N terminal like PD40 PF07676.12 EIM88864.1 - 0.022 14.7 1.1 14 5.7 0.0 5.2 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EIM88864.1 - 0.024 13.7 0.5 1.5 7.8 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) RAB3GAP2_N PF14655.6 EIM88864.1 - 0.043 13.1 0.0 2.4 7.3 0.0 3.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Utp8 PF10395.9 EIM88864.1 - 0.16 10.4 0.0 18 3.6 0.0 2.8 2 1 0 3 3 3 0 Utp8 family E1-E2_ATPase PF00122.20 EIM88866.1 - 5.2e-46 156.4 4.8 1.5e-45 155.0 4.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EIM88866.1 - 3.9e-25 89.4 0.0 6.3e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EIM88866.1 - 7.7e-08 32.7 0.1 2.7e-07 30.9 0.1 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EIM88866.1 - 0.00016 21.5 1.0 0.0026 17.6 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EIM88866.1 - 0.00021 21.7 0.0 0.00057 20.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1980 PF09323.10 EIM88866.1 - 0.79 9.6 1.9 1.4 8.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ACT_6 PF13740.6 EIM88866.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.1 4 0 0 4 4 4 0 ACT domain DUF4038 PF13204.6 EIM88867.1 - 8.4e-80 268.7 0.8 1.1e-79 268.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 EIM88867.1 - 2.3e-14 53.1 0.0 6.6e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 Putative collagen-binding domain of a collagenase MFS_1 PF07690.16 EIM88868.1 - 1.8e-28 99.5 34.6 2.5e-28 99.1 34.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DPBB_1 PF03330.18 EIM88869.1 - 3.4e-07 30.4 0.1 4.7e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase DUF4179 PF13786.6 EIM88869.1 - 0.042 14.3 0.5 0.071 13.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Kelch_3 PF13415.6 EIM88870.1 - 4.2e-29 100.2 7.7 8.6e-08 32.3 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EIM88870.1 - 1.7e-27 95.1 7.6 2.4e-07 30.6 0.1 6.6 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EIM88870.1 - 3.3e-17 62.1 7.2 8.9e-07 29.0 0.1 5.7 5 1 1 6 6 6 3 Kelch motif DUF4110 PF13422.6 EIM88870.1 - 2.1e-15 56.5 0.2 2.1e-15 56.5 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 EIM88870.1 - 7.4e-15 54.5 10.1 3.7e-05 23.6 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EIM88870.1 - 1.6e-14 53.2 11.5 3e-06 26.7 0.1 5.2 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EIM88870.1 - 1.4e-08 34.4 16.3 0.01 15.8 1.1 5.5 5 2 0 5 5 5 3 Kelch motif CDC45 PF02724.14 EIM88870.1 - 1.2 7.3 8.3 1.9 6.7 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EIM88870.1 - 7.2 5.9 18.1 1 8.7 11.7 2.1 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.25 EIM88873.1 - 5.8e-34 117.6 0.0 6e-24 84.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM88873.1 - 1.3e-10 41.0 0.0 8.5e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIM88873.1 - 0.0022 18.0 0.2 0.0068 16.4 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM88873.1 - 0.097 12.0 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EIM88873.1 - 0.32 10.3 1.7 0.35 10.2 0.0 1.8 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 EIM88875.1 - 2.1e-07 30.7 1.1 6.6e-07 29.1 1.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM88875.1 - 0.017 15.5 3.9 2 8.9 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Bac_rhodopsin PF01036.18 EIM88878.1 - 4e-47 160.6 18.0 5e-47 160.3 18.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein F-box-like PF12937.7 EIM88881.1 - 4.7e-08 32.8 2.3 4.7e-08 32.8 2.3 2.0 2 0 0 2 2 2 1 F-box-like DUF1192 PF06698.11 EIM88882.1 - 0.063 13.3 1.3 0.13 12.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Adeno_E3_CR2 PF02439.15 EIM88882.1 - 0.067 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 bZIP_2 PF07716.15 EIM88882.1 - 0.13 12.4 1.0 0.21 11.7 1.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper ERG2_Sigma1R PF04622.12 EIM88883.1 - 5.7e-97 323.1 0.0 6.8e-97 322.9 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein SLATT_1 PF18181.1 EIM88883.1 - 0.17 11.8 0.3 0.28 11.1 0.3 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 ERG2_Sigma1R PF04622.12 EIM88884.1 - 8e-87 290.0 0.0 9.6e-87 289.7 0.0 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Histone PF00125.24 EIM88885.1 - 1.1e-23 84.1 4.0 1.4e-23 83.7 4.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIM88885.1 - 3.6e-06 27.2 0.1 3.6e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EIM88885.1 - 0.00048 20.6 0.0 0.00077 19.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EIM88885.1 - 0.0059 16.6 0.6 0.0071 16.4 0.6 1.1 1 0 0 1 1 1 1 YscO-like protein Bt_P21 PF05560.11 EIM88885.1 - 0.091 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone PF00125.24 EIM88886.1 - 3.6e-18 66.2 0.0 4.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EIM88886.1 - 6.9e-18 64.1 0.9 1.3e-17 63.2 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EIM88886.1 - 3.1e-06 27.4 0.0 4.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PWI PF01480.17 EIM88888.1 - 4.7e-28 97.3 0.0 8.3e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 PWI domain DUF5320 PF17253.2 EIM88888.1 - 0.095 13.8 4.0 0.24 12.5 4.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Granulin PF00396.18 EIM88889.1 - 0.061 13.7 1.3 0.11 12.8 1.3 1.4 1 0 0 1 1 1 0 Granulin F-box-like PF12937.7 EIM88890.1 - 4.5e-08 32.8 0.3 4.5e-08 32.8 0.3 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM88890.1 - 0.014 15.9 0.1 2.7 8.5 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) MR_MLE_C PF13378.6 EIM88892.1 - 1.4e-52 178.5 0.0 1.8e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EIM88892.1 - 2.6e-19 69.6 0.0 8.9e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain EMP24_GP25L PF01105.24 EIM88893.1 - 8.1e-37 126.9 0.0 9.1e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TRPM_tetra PF16519.5 EIM88893.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Trimer_CC PF08954.11 EIM88893.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Trimerisation motif F-box-like PF12937.7 EIM88894.1 - 9.8e-07 28.6 0.9 3.8e-06 26.7 0.9 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM88894.1 - 0.00082 19.2 0.1 0.0028 17.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EIM88894.1 - 0.00087 19.2 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 F-box Sporozoite_P67 PF05642.11 EIM88894.1 - 5.4 5.0 5.2 6.9 4.6 5.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box-like PF12937.7 EIM88895.1 - 6.4e-10 38.8 3.5 1.2e-09 37.9 3.5 1.5 1 0 0 1 1 1 1 F-box-like ABC_tran PF00005.27 EIM88897.1 - 1.8e-47 161.3 0.0 6.7e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIM88897.1 - 1.7e-38 132.9 25.7 6.2e-22 78.5 3.6 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EIM88897.1 - 3.7e-09 36.4 0.0 0.0056 16.1 0.4 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIM88897.1 - 0.00012 21.7 0.0 0.049 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM88897.1 - 0.0015 18.8 0.9 4.4 7.6 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EIM88897.1 - 0.0033 17.1 1.5 0.26 11.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 EIM88897.1 - 0.033 13.9 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EIM88897.1 - 0.039 13.0 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 EIM88897.1 - 0.039 13.3 1.2 4.8 6.4 0.0 2.7 3 0 0 3 3 3 0 KaiC DUF87 PF01935.17 EIM88897.1 - 0.04 14.0 0.3 0.1 12.7 0.3 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 EIM88897.1 - 0.089 13.2 0.1 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EIM88897.1 - 0.097 13.2 0.2 8.4 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIM88897.1 - 0.12 11.6 1.1 2.3 7.3 0.0 2.8 4 0 0 4 4 4 0 NB-ARC domain RsgA_GTPase PF03193.16 EIM88897.1 - 0.13 12.2 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_21 PF13304.6 EIM88897.1 - 0.21 11.4 1.1 88 2.8 0.0 3.8 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 EIM88897.1 - 0.28 10.4 1.1 7.7 5.6 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 EIM88897.1 - 2.4 7.7 3.7 1.9 8.1 0.5 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sugar_tr PF00083.24 EIM88898.1 - 2.1e-95 320.2 21.2 2.7e-95 319.9 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM88898.1 - 5.7e-26 91.3 43.4 7.4e-21 74.5 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EIM88898.1 - 0.015 15.5 0.9 0.015 15.5 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF697 PF05128.12 EIM88898.1 - 0.06 13.1 0.5 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Dus PF01207.17 EIM88899.1 - 8.3e-55 186.0 0.0 9.4e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 EIM88899.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EIM88899.1 - 0.032 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 EIM88899.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Aldo_ket_red PF00248.21 EIM88900.1 - 3.5e-68 229.9 0.0 4e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM88901.1 - 1.2e-67 228.2 0.0 1.3e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2 PF00096.26 EIM88902.1 - 6.6e-09 35.7 18.5 0.0004 20.7 0.4 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EIM88902.1 - 2.3e-05 24.1 4.4 3.7e-05 23.4 0.7 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EIM88902.1 - 8e-05 23.2 13.4 0.0095 16.7 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EIM88902.1 - 0.00086 19.6 4.6 0.0023 18.2 4.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 EIM88902.1 - 0.25 11.7 4.5 0.63 10.4 4.5 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 EIM88902.1 - 2 8.5 5.3 7.7 6.6 0.7 2.6 3 0 0 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 EIM88902.1 - 3.6 8.1 5.8 2.5 8.6 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SPC25 PF06703.11 EIM88903.1 - 1.4e-51 174.5 0.0 1.8e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Amino_oxidase PF01593.24 EIM88904.1 - 4.8e-20 72.3 0.0 6.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIM88904.1 - 2.3e-12 46.9 0.0 4.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM88904.1 - 9.3e-07 28.7 0.4 1.4e-06 28.1 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM88904.1 - 0.00041 20.4 0.1 0.0014 18.6 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EIM88904.1 - 0.00044 19.6 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EIM88904.1 - 0.002 17.4 0.0 0.0054 16.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM88904.1 - 0.0088 15.4 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM88904.1 - 0.01 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 EIM88904.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 EIM88904.1 - 0.024 13.5 0.0 0.024 13.5 0.0 1.8 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EIM88904.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EIM88904.1 - 0.029 14.9 0.3 0.34 11.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM88904.1 - 0.03 13.0 0.0 0.056 12.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein HMG_CoA_synt_N PF01154.17 EIM88905.1 - 5.6e-82 273.8 0.0 9.1e-82 273.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EIM88905.1 - 2.8e-80 269.9 0.8 5.4e-80 269.0 0.8 1.5 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Terpene_synth_C PF03936.16 EIM88906.1 - 0.013 14.9 1.5 0.03 13.7 1.5 1.8 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain HU-CCDC81_bac_2 PF18175.1 EIM88906.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 EthD PF07110.11 EIM88907.1 - 3.5e-14 53.7 0.1 4.6e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EIM88907.1 - 3.1e-05 24.4 0.0 4.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase p450 PF00067.22 EIM88908.1 - 9.8e-79 265.2 0.0 1.1e-78 265.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EIM88909.1 - 9.7e-29 100.6 0.0 1.4e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM88909.1 - 3.4e-12 46.6 0.0 8.6e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM88909.1 - 0.0044 17.3 0.0 0.096 12.9 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EIM88909.1 - 0.0059 15.7 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.22 EIM88910.1 - 1.9e-75 254.4 0.0 2.4e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM88911.1 - 2.9e-72 243.9 0.0 3.6e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_13 PF11972.8 EIM88911.1 - 0.17 12.0 0.4 1 9.5 0.2 2.3 2 0 0 2 2 2 0 HTH DNA binding domain p450 PF00067.22 EIM88912.1 - 4.7e-68 230.0 0.0 5.7e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EIM88913.1 - 4.5e-18 65.3 1.1 2.3e-17 63.1 0.5 2.3 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 EIM88913.1 - 4e-07 30.0 0.3 8.6e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 EIM88914.1 - 1.5e-32 113.0 55.1 2.4e-32 112.2 52.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Cecropin PF00272.19 EIM88914.1 - 0.45 10.3 1.7 0.88 9.3 1.7 1.5 1 0 0 1 1 1 0 Cecropin family adh_short PF00106.25 EIM88915.1 - 4.5e-41 140.5 0.1 5.3e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM88915.1 - 1.4e-33 116.4 0.0 1.8e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM88915.1 - 4.3e-15 56.1 0.0 7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM88915.1 - 7.6e-05 22.0 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EIM88915.1 - 0.00092 18.7 0.3 0.0032 17.0 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ubiquitin PF00240.23 EIM88917.1 - 5.5e-27 93.3 0.0 6.1e-25 86.8 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EIM88917.1 - 1.7e-09 37.4 0.7 3.3e-08 33.2 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Prok-RING_4 PF14447.6 EIM88917.1 - 0.011 15.5 8.7 0.016 15.1 7.6 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Ubiquitin_2 PF14560.6 EIM88917.1 - 0.025 15.1 0.0 0.089 13.3 0.0 1.9 2 1 0 2 2 2 0 Ubiquitin-like domain zf-C3HC4_3 PF13920.6 EIM88917.1 - 0.2 11.5 8.7 0.19 11.6 7.2 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM88917.1 - 2.3 8.3 10.0 6.5 6.8 10.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM88917.1 - 8 6.4 8.0 18 5.3 8.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cu_amine_oxid PF01179.20 EIM88918.1 - 1.1e-123 413.3 0.0 1.3e-123 412.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EIM88918.1 - 2.6e-06 27.1 0.0 7.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EIM88918.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain PCI PF01399.27 EIM88919.1 - 8e-23 81.0 0.0 2.7e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 EIM88919.1 - 6.1e-20 71.4 0.2 6.1e-20 71.4 0.2 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 EIM88919.1 - 0.029 14.5 0.1 0.12 12.6 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma70_r1_2 PF00140.20 EIM88919.1 - 0.2 11.7 2.4 0.89 9.6 2.4 2.2 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 p450 PF00067.22 EIM88920.1 - 9.8e-69 232.3 0.0 2.8e-68 230.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.10 EIM88920.1 - 0.1 13.0 1.5 0.28 11.6 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) PHD PF00628.29 EIM88921.1 - 8.5e-07 28.8 3.7 1.9e-06 27.7 3.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EIM88921.1 - 0.0036 17.0 0.9 0.0087 15.7 0.9 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Chromo PF00385.24 EIM88921.1 - 0.0077 16.1 6.8 0.025 14.5 6.8 1.9 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.6 EIM88921.1 - 1.1 9.7 3.6 2.2 8.7 3.6 1.5 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 EIM88921.1 - 1.4 8.6 4.7 2.5 7.7 4.7 1.4 1 0 0 1 1 1 0 PHD-finger Ribophorin_II PF05817.14 EIM88923.1 - 3.5e-32 111.8 0.0 4.1e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_47 PF01532.20 EIM88924.1 - 5.9e-121 404.6 0.0 6.7e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF285 PF03382.14 EIM88924.1 - 0.02 14.7 0.8 0.1 12.3 0.9 2.1 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 F-box-like PF12937.7 EIM88925.1 - 0.00045 20.0 0.2 0.001 18.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM88925.1 - 0.069 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 F-box domain CpXC PF14353.6 EIM88925.1 - 0.1 12.6 1.8 1.5 8.9 0.1 2.9 2 0 0 2 2 2 0 CpXC protein Sec20 PF03908.13 EIM88926.1 - 8.8e-17 60.8 1.6 8.8e-17 60.8 1.6 2.4 2 0 0 2 2 2 1 Sec20 FAM184 PF15665.5 EIM88926.1 - 0.068 12.9 3.6 0.099 12.4 3.6 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Apq12 PF12716.7 EIM88926.1 - 0.84 9.6 4.1 1.7 8.6 4.1 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Spt20 PF12090.8 EIM88927.1 - 8.2e-25 87.8 0.0 9e-14 51.6 0.0 8.9 3 2 2 5 5 5 2 Spt20 family Mem_trans PF03547.18 EIM88928.1 - 6.3e-37 126.9 2.1 8.1e-36 123.2 2.1 2.4 1 1 0 1 1 1 1 Membrane transport protein FA_desaturase PF00487.24 EIM88928.1 - 2.2 8.0 9.2 31 4.3 0.0 3.1 2 1 0 3 3 3 0 Fatty acid desaturase zf-C3HC4_3 PF13920.6 EIM88929.1 - 2.2e-13 49.8 17.8 4.5e-13 48.8 5.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM88929.1 - 8e-10 38.4 5.2 8e-10 38.4 5.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 EIM88929.1 - 2e-08 34.3 6.5 2e-08 34.3 6.5 2.6 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 EIM88929.1 - 5e-07 30.0 5.2 5e-07 30.0 5.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EIM88929.1 - 5.5e-05 23.0 6.0 5.5e-05 23.0 6.0 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 EIM88929.1 - 0.00011 22.3 3.3 0.00011 22.3 3.3 3.3 3 1 0 3 3 2 1 FYVE-type zinc finger Peptidase_S30 PF01577.16 EIM88929.1 - 0.0022 17.6 2.9 0.0035 17.0 2.9 1.2 1 0 0 1 1 1 1 Potyvirus P1 protease zf-C3HC4_2 PF13923.6 EIM88929.1 - 0.0024 17.7 6.2 0.0024 17.7 6.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 EIM88929.1 - 0.019 14.6 1.9 0.019 14.6 1.9 2.7 2 0 0 2 2 2 0 P-11 zinc finger SAP PF02037.27 EIM88929.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 SAP domain DUF4518 PF15008.6 EIM88929.1 - 0.22 10.7 0.6 2.2 7.4 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) SAPS PF04499.15 EIM88929.1 - 0.26 10.0 6.0 0.35 9.6 6.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-RING_5 PF14634.6 EIM88929.1 - 0.85 9.6 22.6 0.077 13.0 4.9 2.6 2 0 0 2 2 2 0 zinc-RING finger domain MCU PF04678.13 EIM88929.1 - 8.4 6.5 8.1 13 5.8 8.1 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DDRGK PF09756.9 EIM88929.1 - 8.4 5.9 20.5 13 5.3 20.5 1.3 1 0 0 1 1 1 0 DDRGK domain ADH_N PF08240.12 EIM88931.1 - 1.3e-29 102.3 4.0 2.2e-29 101.5 4.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM88931.1 - 9.1e-25 87.1 1.0 1.5e-24 86.4 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM88931.1 - 3e-05 25.1 0.1 4.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EIM88931.1 - 0.021 14.3 0.5 0.15 11.5 0.4 2.4 2 1 0 2 2 2 0 short chain dehydrogenase TTC5_OB PF16669.5 EIM88931.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain Zn_clus PF00172.18 EIM88932.1 - 0.0031 17.6 13.2 0.005 16.9 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pol_alpha_B_N PF08418.10 EIM88932.1 - 4.1 7.3 8.4 7 6.5 8.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CBS PF00571.28 EIM88935.1 - 1.8e-14 53.9 0.0 0.0017 18.8 0.0 4.4 4 0 0 4 4 4 3 CBS domain Cys_Met_Meta_PP PF01053.20 EIM88937.1 - 1.8e-24 86.0 0.0 2.4e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cupin_3 PF05899.12 EIM88937.1 - 0.096 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Thaumatin PF00314.17 EIM88938.1 - 1.7e-14 54.0 9.9 2.1e-14 53.7 9.9 1.2 1 0 0 1 1 1 1 Thaumatin family zf-MYND PF01753.18 EIM88939.1 - 1.8e-07 31.1 11.6 1.8e-07 31.1 11.6 1.9 2 0 0 2 2 2 1 MYND finger Peptidase_M66 PF10462.9 EIM88939.1 - 0.0076 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 ADD_DNMT3 PF17980.1 EIM88939.1 - 0.011 15.7 2.1 0.026 14.5 2.1 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Ecl1 PF12855.7 EIM88939.1 - 0.029 15.5 3.3 0.065 14.4 3.3 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF1682 PF07946.14 EIM88939.1 - 0.14 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GST_N_3 PF13417.6 EIM88940.1 - 7.8e-09 35.8 0.1 1.6e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM88940.1 - 0.00073 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3945 PF13101.6 EIM88940.1 - 0.15 11.8 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) DUF5056 PF16479.5 EIM88941.1 - 0.024 14.9 1.1 0.061 13.5 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) DUF423 PF04241.15 EIM88941.1 - 0.036 14.3 2.1 0.05 13.8 0.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF423) MFS_5 PF05631.14 EIM88942.1 - 1.4e-68 231.4 7.9 1.4e-54 185.3 1.0 2.8 2 1 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EIM88942.1 - 1.1e-16 60.8 38.4 1.1e-16 60.8 38.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Rubella_E2 PF05749.11 EIM88942.1 - 0.076 12.5 3.9 0.24 10.8 3.9 1.8 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 CopD PF05425.13 EIM88942.1 - 1.3 9.5 14.8 0.49 10.8 1.0 4.8 5 0 0 5 5 5 0 Copper resistance protein D Aldedh PF00171.22 EIM88943.1 - 3.8e-85 286.1 0.0 4.6e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_4 PF07993.12 EIM88944.1 - 7.2e-33 113.8 0.0 1.3e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM88944.1 - 1.4e-15 56.9 0.0 5.2e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM88944.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM88944.1 - 0.00043 20.6 2.6 0.001 19.4 0.0 3.0 3 1 0 3 3 3 1 Phosphopantetheine attachment site KR PF08659.10 EIM88944.1 - 0.0013 18.6 0.0 0.0051 16.7 0.0 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EIM88944.1 - 0.041 13.0 0.0 0.095 11.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EIM88944.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 EIM88945.1 - 6.8e-48 163.4 46.6 6.8e-48 163.4 46.6 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM88945.1 - 1.5e-19 69.9 18.1 2.1e-19 69.4 18.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIM88945.1 - 6e-11 41.9 12.1 6e-11 41.9 12.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EIM88945.1 - 0.00021 20.0 1.3 0.00021 20.0 1.3 3.6 1 1 0 3 3 3 2 MFS/sugar transport protein HlyIII PF03006.20 EIM88945.1 - 0.035 13.8 0.2 0.035 13.8 0.2 3.8 2 1 3 5 5 5 0 Haemolysin-III related GMC_oxred_N PF00732.19 EIM88948.1 - 6.7e-65 219.4 0.0 1.2e-64 218.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM88948.1 - 7.1e-40 136.8 0.0 1.4e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EIM88948.1 - 0.00022 20.9 1.3 0.094 12.3 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM88948.1 - 0.00028 20.1 0.2 0.00054 19.1 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EIM88948.1 - 0.0011 19.1 0.4 0.0028 17.8 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM88948.1 - 0.0019 17.5 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EIM88948.1 - 0.02 14.1 0.1 0.055 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM88948.1 - 0.044 12.9 2.1 0.11 11.5 0.8 1.9 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.22 EIM88949.1 - 2.8e-58 197.8 0.0 3.1e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 EIM88950.1 - 4.1e-22 78.3 0.0 1.9e-17 62.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM88950.1 - 4.8e-20 72.0 0.0 7.6e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM88950.1 - 5.2e-13 48.9 0.0 3.6e-09 36.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM88950.1 - 1.8e-10 40.5 0.0 4.9e-07 29.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EIM88950.1 - 4.5e-07 30.0 0.1 0.00041 20.4 0.0 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EIM88950.1 - 0.002 18.6 2.1 0.51 10.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM88950.1 - 0.0026 17.8 0.1 0.16 11.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.18 EIM88950.1 - 0.0093 16.2 0.0 0.79 10.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 EIM88950.1 - 0.016 14.6 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EIM88950.1 - 0.026 14.7 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM88950.1 - 0.055 12.7 0.1 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EIM88950.1 - 0.11 11.6 0.7 1.9 7.5 0.0 2.8 4 0 0 4 4 4 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EIM88950.1 - 0.14 12.6 0.0 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EIM88950.1 - 0.19 11.6 0.1 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 EIM88951.1 - 2.5e-52 178.1 0.0 3.3e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM88951.1 - 1.9e-31 109.5 0.0 3.3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM88951.1 - 0.019 15.2 0.8 0.08 13.2 0.8 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sec_GG PF07549.14 EIM88951.1 - 0.11 12.1 1.1 0.24 11.0 1.1 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif Glyco_hydro_88 PF07470.13 EIM88952.1 - 1.6e-23 83.4 0.5 1.6e-23 83.4 0.5 1.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_16 PF00722.21 EIM88953.1 - 4.7e-06 26.2 0.2 9.8e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CNH PF00780.22 EIM88954.1 - 1.7e-16 60.7 0.0 2.5e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EIM88955.1 - 9.9e-09 35.6 0.0 2.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EIM88955.1 - 3.4e-05 24.1 0.0 0.0022 18.2 0.0 3.1 3 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Ndc1_Nup PF09531.10 EIM88955.1 - 0.16 10.7 4.9 0.24 10.1 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EIM88955.1 - 0.9 8.7 15.9 1.4 8.0 15.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2477 PF10631.9 EIM88955.1 - 3.2 8.4 6.8 2 9.1 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) SPX PF03105.19 EIM88955.1 - 8.9 6.1 11.3 15 5.3 11.3 1.4 1 0 0 1 1 1 0 SPX domain RabGAP-TBC PF00566.18 EIM88956.1 - 1.1e-18 67.7 0.0 1.7e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BUD22 PF09073.10 EIM88956.1 - 3.1 7.1 37.4 0.04 13.3 3.5 3.2 3 0 0 3 3 3 0 BUD22 Perilipin PF03036.16 EIM88960.1 - 2.6e-09 36.6 0.2 2.6e-09 36.6 0.2 3.6 2 2 2 4 4 4 3 Perilipin family Apolipoprotein PF01442.18 EIM88960.1 - 0.053 13.4 5.7 0.66 9.8 4.0 2.8 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EIM88960.1 - 1.3 9.7 5.5 2.6 8.6 0.9 3.0 3 1 0 3 3 3 0 YtxH-like protein NmrA PF05368.13 EIM88961.1 - 2.6e-29 102.5 0.0 3.3e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM88961.1 - 1.4e-10 41.4 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIM88961.1 - 2.2e-05 23.6 0.1 3.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EIM88961.1 - 0.0068 16.7 0.2 0.013 15.8 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EIM88961.1 - 0.0076 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EIM88961.1 - 0.04 13.1 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.13 EIM88962.1 - 9.7e-29 100.6 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM88962.1 - 7.6e-11 42.2 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIM88962.1 - 8.1e-05 21.8 0.1 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EIM88962.1 - 0.054 13.8 0.1 0.36 11.1 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PTP_tm PF18861.1 EIM88963.1 - 0.011 15.7 1.7 0.018 15.1 1.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 EIM88963.1 - 0.046 14.6 0.8 0.071 14.0 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 EIM88963.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SIT PF15330.6 EIM88964.1 - 0.00028 21.3 0.2 0.00047 20.6 0.2 1.4 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT DUF5305 PF17231.2 EIM88964.1 - 0.00057 19.4 0.1 0.0012 18.2 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Glycophorin_A PF01102.18 EIM88964.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A YhfC PF10086.9 EIM88964.1 - 0.03 13.7 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease Rax2 PF12768.7 EIM88964.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 EIM88964.1 - 0.041 13.3 1.4 0.072 12.5 1.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 EIM88964.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EIM88964.1 - 0.16 12.9 0.0 0.2 12.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 EIM88964.1 - 0.27 10.7 0.0 0.36 10.3 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LapA_dom PF06305.11 EIM88964.1 - 0.34 10.8 2.1 0.57 10.0 2.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AA_permease_2 PF13520.6 EIM88966.1 - 1.2e-72 245.2 53.9 1.5e-72 244.8 53.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM88966.1 - 4.6e-19 68.4 47.2 6.3e-19 67.9 47.2 1.1 1 0 0 1 1 1 1 Amino acid permease Sec23_trunk PF04811.15 EIM88967.1 - 4.1e-75 252.5 0.0 5.8e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EIM88967.1 - 1.3e-29 102.8 0.0 2.7e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EIM88967.1 - 6.9e-26 90.1 0.2 1.5e-25 89.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EIM88967.1 - 8.4e-16 57.7 7.0 1.5e-15 56.9 7.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EIM88967.1 - 4.9e-13 48.8 0.0 1.6e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat 5_3_exonuc PF01367.20 EIM88968.1 - 0.033 14.8 0.2 0.29 11.8 0.0 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Fucokinase PF07959.12 EIM88968.1 - 0.12 11.3 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase Sec20 PF03908.13 EIM88968.1 - 0.15 12.0 0.1 3.3 7.7 0.0 3.0 1 1 1 2 2 2 0 Sec20 NAD_binding_6 PF08030.12 EIM88969.1 - 7.8e-37 126.8 0.0 1.2e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIM88969.1 - 1.8e-23 82.7 0.1 5.4e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EIM88969.1 - 2.4e-16 60.0 16.2 2.4e-16 60.0 16.2 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component O-FucT PF10250.9 EIM88969.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase FMO-like PF00743.19 EIM88970.1 - 3e-29 101.8 0.0 1.6e-20 73.0 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM88970.1 - 5.5e-12 45.6 0.0 2.1e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM88970.1 - 0.0003 20.1 0.4 0.021 14.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIM88970.1 - 0.0013 18.0 0.0 0.053 12.7 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM88970.1 - 0.0041 17.1 1.9 0.54 10.2 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 EIM88970.1 - 0.025 13.8 1.1 1.5 8.0 0.2 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 EIM88970.1 - 0.037 14.3 0.0 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PMD PF10536.9 EIM88970.1 - 0.081 12.0 0.4 0.12 11.5 0.4 1.1 1 0 0 1 1 1 0 Plant mobile domain p450 PF00067.22 EIM88971.1 - 2.2e-68 231.1 0.0 2.9e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RSN1_7TM PF02714.15 EIM88972.1 - 1.8e-81 273.5 24.3 2.9e-81 272.8 24.3 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EIM88972.1 - 3.8e-36 124.2 5.7 3.8e-36 124.2 5.7 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EIM88972.1 - 1.6e-28 100.1 1.4 4.8e-21 75.8 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EIM88972.1 - 2.7e-09 37.1 0.6 9.3e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF2892 PF11127.8 EIM88972.1 - 4.4 7.4 6.6 0.52 10.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Syntaxin-6_N PF09177.11 EIM88973.1 - 1.3e-26 93.0 4.4 1.6e-25 89.5 0.4 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EIM88973.1 - 8.9e-09 35.2 0.6 2.4e-08 33.9 0.6 1.8 1 0 0 1 1 1 1 SNARE domain Spc7 PF08317.11 EIM88973.1 - 0.0033 16.4 3.2 0.16 10.9 0.1 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Use1 PF09753.9 EIM88973.1 - 0.0043 16.8 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF3040 PF11239.8 EIM88973.1 - 0.0067 16.7 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) FliJ PF02050.16 EIM88973.1 - 0.016 15.4 6.1 0.92 9.7 1.2 3.1 2 2 1 3 3 3 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.12 EIM88973.1 - 0.018 15.1 6.9 0.18 11.9 1.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 EIM88973.1 - 0.022 14.3 3.0 0.071 12.6 0.1 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Laminin_I PF06008.14 EIM88973.1 - 0.05 13.3 2.2 2.8 7.6 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain I QRPTase_C PF01729.19 EIM88973.1 - 0.061 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain APG17 PF04108.12 EIM88973.1 - 0.061 12.4 2.8 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Apg17 Phage_GP20 PF06810.11 EIM88973.1 - 0.071 12.9 1.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Rx_N PF18052.1 EIM88973.1 - 0.074 13.3 2.6 0.61 10.4 0.1 2.8 3 0 0 3 3 3 0 Rx N-terminal domain XhlA PF10779.9 EIM88973.1 - 0.085 13.1 3.5 2.1 8.6 0.8 2.6 2 1 0 2 2 2 0 Haemolysin XhlA EF-hand_14 PF17959.1 EIM88973.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain DUF3584 PF12128.8 EIM88973.1 - 0.11 10.0 1.6 3.6 5.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Prominin PF05478.11 EIM88973.1 - 0.14 10.1 0.3 1 7.2 0.0 1.9 2 0 0 2 2 2 0 Prominin DUF2207 PF09972.9 EIM88973.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FPP PF05911.11 EIM88973.1 - 0.2 9.8 4.1 0.15 10.2 0.2 1.9 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 EIM88973.1 - 0.22 12.0 2.7 4.9 7.6 0.2 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1640 PF07798.11 EIM88973.1 - 0.28 11.2 5.2 1.3 9.0 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) KxDL PF10241.9 EIM88973.1 - 0.34 11.2 4.5 4.1 7.8 1.2 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein DLP_helical PF18709.1 EIM88973.1 - 0.36 10.0 2.4 0.49 9.5 0.1 2.0 2 0 0 2 2 2 0 Dynamin-like helical domain TBCA PF02970.16 EIM88973.1 - 1.5 9.2 7.9 7.5 7.0 3.8 3.0 2 1 0 2 2 2 0 Tubulin binding cofactor A Jnk-SapK_ap_N PF09744.9 EIM88973.1 - 1.7 8.9 5.7 0.43 10.8 0.3 2.1 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4618 PF15397.6 EIM88973.1 - 1.7 8.0 6.7 7.2 5.9 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF883 PF05957.13 EIM88973.1 - 2 9.1 8.1 2.2 8.9 0.6 3.3 3 1 0 4 4 3 0 Bacterial protein of unknown function (DUF883) DUF4200 PF13863.6 EIM88973.1 - 2 8.8 9.6 3.9 7.9 2.1 2.8 3 1 0 3 3 2 0 Domain of unknown function (DUF4200) PspA_IM30 PF04012.12 EIM88973.1 - 2.4 7.7 7.9 5.3 6.5 0.8 2.6 2 1 0 2 2 2 0 PspA/IM30 family DUF641 PF04859.12 EIM88973.1 - 4 7.8 5.5 2.9 8.2 0.2 2.5 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) DUF4140 PF13600.6 EIM88973.1 - 4.6 7.7 7.1 0.35 11.3 1.1 2.2 3 1 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) p450 PF00067.22 EIM88974.1 - 0.0017 17.2 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM88975.1 - 8.3e-49 166.6 0.0 1e-48 166.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PCMT PF01135.19 EIM88976.1 - 8e-72 241.4 0.0 9.3e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EIM88976.1 - 3.1e-07 30.3 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM88976.1 - 2.2e-05 25.1 0.0 5.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EIM88976.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM88976.1 - 0.00027 21.5 0.0 0.00071 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM88976.1 - 0.00036 20.4 0.0 0.00045 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIM88976.1 - 0.003 17.0 0.0 0.031 13.7 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EIM88976.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EIM88976.1 - 0.096 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EIM88976.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 EIM88976.1 - 0.17 11.7 0.0 0.54 10.0 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_18 PF12847.7 EIM88976.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 EIM88976.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF4470 PF14737.6 EIM88977.1 - 1.2e-24 86.3 0.0 2.3e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EIM88977.1 - 2e-10 40.6 14.0 4.6e-10 39.4 14.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM88977.1 - 2.9 8.2 11.3 7.5 7.0 11.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 EIM88978.1 - 3.9e-06 26.7 0.1 1.5e-05 24.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like MAM33 PF02330.16 EIM88979.1 - 1.1e-69 234.7 0.7 1.2e-69 234.5 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein FabA PF07977.13 EIM88979.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 FabA-like domain ThrE PF06738.12 EIM88982.1 - 1e-32 113.4 9.0 1e-32 113.4 9.0 2.4 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM88982.1 - 0.0091 16.1 29.6 0.061 13.5 9.2 2.7 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE Sugar_tr PF00083.24 EIM88983.1 - 5.5e-84 282.6 22.3 6.3e-84 282.4 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM88983.1 - 3.6e-20 72.2 35.6 2.2e-18 66.3 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PRRSV_2b PF07069.11 EIM88983.1 - 1.4 9.4 5.2 0.42 11.1 0.6 2.5 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Lig_chan PF00060.26 EIM88983.1 - 1.7 8.5 6.9 23 4.8 0.1 3.3 3 0 0 3 3 3 0 Ligand-gated ion channel GRAB PF10375.9 EIM88984.1 - 9e-08 31.7 1.7 2.1e-07 30.6 1.7 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 EIM88984.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 GRIP domain Laminin_II PF06009.12 EIM88984.1 - 0.33 11.0 17.9 0.85 9.6 5.3 2.7 2 0 0 2 2 2 0 Laminin Domain II Bcr-Abl_Oligo PF09036.10 EIM88984.1 - 0.63 10.1 12.0 0.22 11.6 0.3 4.2 2 2 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Tho2 PF11262.8 EIM88984.1 - 0.67 9.1 13.6 0.047 12.9 2.1 2.4 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Seryl_tRNA_N PF02403.22 EIM88984.1 - 4.5 7.6 22.6 0.27 11.5 4.4 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain F-box PF00646.33 EIM88985.1 - 6.4e-07 29.1 0.8 2.4e-06 27.3 0.5 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM88985.1 - 0.00017 21.4 1.3 0.00049 19.9 1.3 1.8 1 0 0 1 1 1 1 F-box-like Histone PF00125.24 EIM88986.1 - 3.2e-22 79.3 2.8 4.4e-22 78.8 2.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIM88986.1 - 2.3e-06 27.8 0.1 5.9e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EIM88986.1 - 0.00086 19.8 0.0 0.0014 19.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 EIM88986.1 - 0.039 14.2 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein Bt_P21 PF05560.11 EIM88986.1 - 0.057 13.0 0.1 0.073 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone PF00125.24 EIM88987.1 - 2.2e-18 66.9 0.0 2.8e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EIM88987.1 - 2e-17 62.6 0.3 3.9e-17 61.7 0.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EIM88987.1 - 3.2e-06 27.3 0.0 4.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-MYND PF01753.18 EIM88988.1 - 1.1e-06 28.6 14.2 2.4e-06 27.5 14.2 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 EIM88989.1 - 2.8e-07 30.5 15.3 7.6e-07 29.1 15.3 1.8 1 0 0 1 1 1 1 MYND finger WD40 PF00400.32 EIM88990.1 - 3.7e-11 43.4 14.0 0.00016 22.4 0.0 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM88990.1 - 1.2e-07 31.9 0.1 0.075 13.3 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Arylsulfotrans PF05935.11 EIM88990.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) zf-CRD PF17979.1 EIM88991.1 - 0.031 14.4 2.6 0.1 12.7 0.8 2.4 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions zinc-ribbons_6 PF07191.12 EIM88991.1 - 2.1 8.4 7.6 1.3e+02 2.6 7.6 2.4 1 1 0 1 1 1 0 zinc-ribbons HECT_2 PF09814.9 EIM88992.1 - 1.1e-47 162.7 0.0 2.1e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PLA2_B PF01735.18 EIM88993.1 - 1e-65 222.1 14.9 2.8e-62 210.7 14.9 3.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EIM88993.1 - 0.0059 16.8 1.0 0.0093 16.2 0.5 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase PLA2_B PF01735.18 EIM88994.1 - 4.3e-65 220.0 16.0 2.9e-62 210.7 16.0 3.1 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Homoserine_dh PF00742.19 EIM88995.1 - 2e-48 164.6 0.0 2.6e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EIM88995.1 - 4.1e-18 66.1 0.0 7.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ArsB PF02040.15 EIM88996.1 - 1.4e-11 44.4 14.3 1e-05 25.1 1.1 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 EIM88996.1 - 1.7e-08 34.1 7.4 4.9e-08 32.5 7.4 1.8 1 1 0 1 1 1 1 Citrate transporter MSP1a PF11670.8 EIM88997.1 - 0.52 9.6 4.3 2 7.7 0.1 2.2 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) PPTA PF01239.22 EIM88998.1 - 3.5e-43 144.1 11.9 1.4e-09 37.3 0.2 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RRM_1 PF00076.22 EIM88999.1 - 5.7e-14 51.7 0.0 7.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM88999.1 - 0.0058 16.5 0.0 0.0097 15.7 0.0 1.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Shadoo PF14999.6 EIM88999.1 - 2 8.5 6.5 1.3 9.1 4.5 1.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RNA_pol_3_Rpc31 PF11705.8 EIM89000.1 - 7.9e-29 101.5 7.6 1.2e-28 101.0 7.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_A4 PF01828.17 EIM89002.1 - 7.2e-78 260.8 19.5 9.1e-78 260.5 19.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_S9 PF00326.21 EIM89003.1 - 1.7e-37 129.0 0.0 3.8e-37 127.8 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 EIM89003.1 - 3.9e-07 29.8 1.2 0.62 10.1 0.0 4.9 4 1 0 4 4 4 2 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 EIM89003.1 - 7.2e-05 22.5 0.4 0.33 10.5 0.0 3.3 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.18 EIM89003.1 - 0.0043 16.6 0.1 0.0076 15.8 0.1 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 EIM89003.1 - 0.03 13.7 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase BAAT_C PF08840.11 EIM89003.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Oxidored_FMN PF00724.20 EIM89005.1 - 3.5e-66 223.8 0.0 4.4e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EIM89005.1 - 0.00048 19.3 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DDE_1 PF03184.19 EIM89006.1 - 7e-08 32.3 0.0 7.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EIM89007.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PLAT PF01477.23 EIM89007.1 - 0.0019 18.8 0.0 0.0019 18.7 0.0 1.1 1 0 0 1 1 1 1 PLAT/LH2 domain Arginase PF00491.21 EIM89008.1 - 0.045 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Arginase family CCDC53 PF10152.9 EIM89008.1 - 0.39 11.1 13.1 0.15 12.5 4.5 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 EIM89008.1 - 8.5 5.9 19.6 0.26 10.9 9.6 2.3 2 0 0 2 2 2 0 Spt20 family 2-oxoacid_dh PF00198.23 EIM89011.1 - 1.1e-57 195.2 0.0 1.6e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EIM89011.1 - 2.8e-17 62.3 1.0 4.7e-17 61.6 1.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 EIM89011.1 - 0.0014 18.5 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 EIM89011.1 - 0.013 16.2 0.0 3.5 8.4 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein SAP18 PF06487.12 EIM89012.1 - 3.7e-32 111.4 0.0 5.4e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Peptidase_M18 PF02127.15 EIM89013.1 - 1e-129 433.2 0.0 1.1e-129 433.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Glyco_transf_20 PF00982.21 EIM89014.1 - 9.9e-145 482.8 0.0 1.6e-144 482.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EIM89014.1 - 1.2e-69 234.0 0.0 5.2e-69 231.9 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase DUF4366 PF14283.6 EIM89014.1 - 6.3 6.8 5.5 18 5.4 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4470 PF14737.6 EIM89016.1 - 8.9e-24 83.5 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EIM89016.1 - 2.1e-08 34.1 13.1 5.2e-08 32.8 13.1 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM89016.1 - 6 7.3 12.0 16 5.9 12.0 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 EIM89017.1 - 1.7e-11 43.8 0.2 5.9e-11 42.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like RRM_1 PF00076.22 EIM89018.1 - 7.9e-47 157.0 0.0 1.2e-15 57.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EIM89018.1 - 0.0084 16.2 0.0 0.13 12.3 0.0 2.8 3 1 0 3 3 3 1 Limkain b1 DUF3343 PF11823.8 EIM89018.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Phage_TAC_13 PF16459.5 EIM89018.1 - 0.026 14.9 0.0 0.48 10.9 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone, TAC gpW PF02831.15 EIM89018.1 - 0.11 12.5 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 gpW PNISR PF15996.5 EIM89018.1 - 1.2 9.4 8.8 2 8.6 8.8 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Apt1 PF10351.9 EIM89018.1 - 1.3 7.7 10.0 1.8 7.3 10.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EIM89018.1 - 3.5 6.3 5.1 4.5 5.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin ThrE PF06738.12 EIM89019.1 - 2.6e-37 128.5 19.6 6.9e-37 127.1 5.4 2.8 2 1 1 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EIM89019.1 - 0.0015 18.7 24.3 0.0041 17.3 7.3 3.0 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE L31 PF09784.9 EIM89019.1 - 0.11 12.9 0.7 0.31 11.5 0.7 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 PH_9 PF15410.6 EIM89022.1 - 0.00064 20.1 0.0 0.00068 20.0 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EIM89022.1 - 0.0025 18.3 0.0 0.0026 18.2 0.0 1.1 1 0 0 1 1 1 1 PH domain Mitoc_mL59 PF18126.1 EIM89025.1 - 2e-37 128.4 3.6 5.3e-37 127.0 3.6 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-MYND PF01753.18 EIM89028.1 - 0.00022 21.2 10.9 0.00022 21.2 10.9 1.9 2 0 0 2 2 2 1 MYND finger TMEM240 PF15207.6 EIM89028.1 - 0.11 12.2 1.0 0.25 11.0 0.1 2.0 2 0 0 2 2 2 0 TMEM240 family DUF2502 PF10697.9 EIM89034.1 - 0.026 14.9 1.6 0.041 14.2 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) DUF1769 PF08588.10 EIM89035.1 - 1.1e-23 83.1 0.3 2.3e-23 82.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF1682 PF07946.14 EIM89035.1 - 7.6 5.6 12.9 11 5.2 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Sdh5 PF03937.16 EIM89038.1 - 6e-28 96.6 0.6 7e-28 96.4 0.6 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Gly_transf_sug PF04488.15 EIM89041.1 - 9.2e-05 23.0 0.0 0.00015 22.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DEAD PF00270.29 EIM89042.1 - 1.3e-42 145.6 0.1 2.3e-42 144.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM89042.1 - 2.1e-27 95.7 0.7 1.3e-26 93.1 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EIM89042.1 - 0.0074 15.7 0.2 0.019 14.3 0.2 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit zf-MYND PF01753.18 EIM89043.1 - 0.96 9.6 16.1 0.075 13.1 11.1 1.8 2 0 0 2 2 2 0 MYND finger zf-MYND PF01753.18 EIM89044.1 - 2.5e-06 27.5 8.7 2.5e-06 27.5 8.7 2.1 2 1 0 2 2 2 1 MYND finger TPR_14 PF13428.6 EIM89044.1 - 0.11 13.3 0.2 0.42 11.6 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat HAD_2 PF13419.6 EIM89045.1 - 5.3e-09 36.4 0.0 1.2e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM89045.1 - 7.3e-06 26.4 0.0 2e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2076 PF09849.9 EIM89046.1 - 0.11 12.5 0.7 0.12 12.4 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EIM89046.1 - 0.18 12.0 4.0 0.46 10.7 4.1 1.6 1 1 1 2 2 2 0 CHCH domain Tim44 PF04280.15 EIM89047.1 - 4.2e-06 26.9 0.1 0.034 14.3 0.0 2.9 3 0 0 3 3 3 2 Tim44-like domain Med3 PF11593.8 EIM89047.1 - 0.2 10.8 0.1 0.31 10.2 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nitroreductase PF00881.24 EIM89048.1 - 1.3e-09 38.3 0.0 1.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.16 EIM89050.1 - 1.5e-38 132.7 48.5 1.5e-38 132.7 48.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM89050.1 - 5.1e-18 64.8 26.6 1.1e-17 63.8 26.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIM89050.1 - 2.4e-13 49.8 12.1 2.4e-13 49.8 12.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5337 PF17272.2 EIM89050.1 - 6.2 6.7 6.9 1.5 8.7 1.9 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5337) GDPD PF03009.17 EIM89051.1 - 4.9e-27 95.3 0.0 7.4e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SAM_MT PF04445.13 EIM89051.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase HhH-GPD PF00730.25 EIM89053.1 - 8.9e-21 74.4 0.0 2.7e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EIM89053.1 - 1.8e-08 33.8 0.0 1e-07 31.4 0.0 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix motif Nitroreductase PF00881.24 EIM89054.1 - 5.7e-15 55.8 0.0 6.6e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family DUF3665 PF12427.8 EIM89054.1 - 0.14 11.9 1.7 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Zf_RING PF16744.5 EIM89055.1 - 0.036 14.2 1.4 0.036 14.2 1.4 1.8 2 1 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 EIM89055.1 - 0.058 13.3 7.3 0.3 11.0 4.0 2.5 2 0 0 2 2 2 0 PHD-finger Tsg PF04668.12 EIM89055.1 - 1.6 9.4 7.3 0.91 10.2 5.2 1.5 1 1 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region dsrm PF00035.26 EIM89057.1 - 0.077 13.7 0.1 0.083 13.6 0.1 1.1 1 0 0 1 1 1 0 Double-stranded RNA binding motif TIP39 PF14980.6 EIM89058.1 - 0.14 12.1 0.5 26 4.8 0.1 2.6 2 0 0 2 2 2 0 TIP39 peptide Sec62 PF03839.16 EIM89059.1 - 3.9e-53 180.2 2.3 8e-53 179.1 2.3 1.5 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 EIM89059.1 - 3.6 6.7 7.7 5.6 6.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) TPR_12 PF13424.6 EIM89060.1 - 1.6e-07 31.5 6.2 0.00061 20.0 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM89060.1 - 1.7e-07 30.8 1.5 0.0092 16.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM89060.1 - 1.8e-05 24.4 0.1 0.049 13.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM89060.1 - 0.00012 21.8 0.8 0.38 10.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 EIM89060.1 - 0.0012 18.9 0.3 0.03 14.4 0.4 2.9 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EIM89060.1 - 0.0027 18.3 2.8 1.2 9.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIM89060.1 - 0.02 14.8 8.0 14 5.7 0.1 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EIM89060.1 - 0.12 12.8 0.0 21 5.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SR-25 PF10500.9 EIM89061.1 - 0.0077 15.9 7.9 0.0077 15.9 7.9 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Myb_DNA-binding PF00249.31 EIM89062.1 - 0.0013 18.9 0.0 0.023 14.9 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain BTV_NS2 PF04514.12 EIM89063.1 - 3.1 6.5 6.9 21 3.8 0.1 2.1 1 1 1 2 2 2 0 Bluetongue virus non-structural protein NS2 HAD_2 PF13419.6 EIM89064.1 - 3.4e-08 33.8 0.0 0.0084 16.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM89064.1 - 0.00035 20.9 0.0 0.0016 18.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM89064.1 - 0.0061 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like WD40 PF00400.32 EIM89066.1 - 8.7e-91 295.4 23.6 3.6e-10 40.3 0.1 10.6 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89066.1 - 7e-34 116.0 0.2 0.00071 19.8 0.0 9.8 1 1 9 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM89066.1 - 5.5e-16 58.4 1.0 0.024 13.6 0.0 8.0 2 2 6 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIM89066.1 - 2.1e-11 43.4 1.2 1.6 8.8 0.1 8.9 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EIM89066.1 - 1.1e-09 38.0 0.0 1.1 8.6 0.0 5.8 2 1 4 6 6 6 3 WD40-like domain NACHT PF05729.12 EIM89066.1 - 1.4e-08 34.9 0.0 2.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 EIM89066.1 - 2.3e-07 29.9 2.1 2.3 6.7 0.0 6.1 3 2 4 7 7 7 2 Nucleoporin Nup120/160 AAA_16 PF13191.6 EIM89066.1 - 4.4e-06 27.2 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Frtz PF11768.8 EIM89066.1 - 1.9e-05 23.2 0.0 1.1 7.5 0.0 4.4 2 2 3 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EIM89066.1 - 6.7e-05 21.6 0.1 0.0018 16.8 0.0 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain DUF5570 PF17731.1 EIM89066.1 - 0.0001 22.4 10.7 1.6 8.8 0.1 5.9 3 2 3 6 6 6 2 Family of unknown function (DUF5570) Proteasome_A_N PF10584.9 EIM89066.1 - 0.00027 20.6 3.6 11 5.8 0.0 6.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PQQ_2 PF13360.6 EIM89066.1 - 0.00054 19.6 1.6 0.048 13.2 0.1 2.9 1 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.11 EIM89066.1 - 0.0016 17.3 0.2 2.4 6.8 0.1 4.2 2 2 2 4 4 4 2 Nup133 N terminal like Ret2_MD PF18528.1 EIM89066.1 - 0.0099 16.2 0.0 61 4.1 0.0 5.6 5 1 2 7 7 7 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF727 PF05303.12 EIM89066.1 - 0.061 13.4 0.0 12 6.1 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF727) EXS PF03124.14 EIM89067.1 - 5.5e-72 242.9 14.9 7.3e-72 242.5 14.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EIM89067.1 - 3.9e-40 139.0 12.0 3e-39 136.1 12.0 2.1 1 1 0 1 1 1 1 SPX domain Menin PF05053.13 EIM89067.1 - 0.1 11.0 1.5 0.2 10.0 1.5 1.5 1 0 0 1 1 1 0 Menin CytochromB561_N PF09786.9 EIM89067.1 - 6.8 5.6 7.7 10 5.0 7.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PHD PF00628.29 EIM89068.1 - 0.014 15.3 5.3 0.017 15.0 0.7 2.4 2 0 0 2 2 2 0 PHD-finger PHD_2 PF13831.6 EIM89068.1 - 0.014 15.0 1.4 0.044 13.3 0.0 2.3 2 0 0 2 2 2 0 PHD-finger Peptidase_S9 PF00326.21 EIM89069.1 - 8.4e-29 100.6 0.0 1.2e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EIM89069.1 - 2.5e-11 43.3 0.1 4e-07 29.5 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM89069.1 - 1.8e-09 37.7 0.2 2.7e-07 30.5 0.4 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM89069.1 - 1.2e-06 29.3 1.4 4.9e-06 27.3 1.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EIM89069.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EIM89069.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 EIM89069.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 EIM89069.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 EIM89069.1 - 0.12 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Vps16_C PF04840.12 EIM89070.1 - 6.5e-84 281.7 0.1 8.1e-84 281.4 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EIM89070.1 - 2.9e-81 273.3 0.0 3.9e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region RIB43A PF05914.12 EIM89070.1 - 0.11 11.2 2.5 0.16 10.7 2.5 1.1 1 0 0 1 1 1 0 RIB43A Arrestin_N PF00339.29 EIM89071.1 - 0.0013 18.8 0.0 0.31 11.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Sugar_tr PF00083.24 EIM89072.1 - 1.5e-94 317.4 16.9 1.8e-94 317.2 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM89072.1 - 1e-38 133.2 36.7 4.5e-37 127.8 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF155 PF02582.14 EIM89073.1 - 4.3e-43 147.4 0.0 7.2e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LIDHydrolase PF10230.9 EIM89073.1 - 0.08 12.5 0.3 0.14 11.6 0.3 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ATP-synt_10 PF05176.14 EIM89075.1 - 6.9e-65 218.8 0.0 8.4e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein DUF4636 PF15468.6 EIM89075.1 - 0.093 12.4 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Histone PF00125.24 EIM89076.1 - 1.4e-17 64.2 0.0 1.8e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EIM89076.1 - 4e-16 58.4 0.2 7.8e-16 57.5 0.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EIM89076.1 - 3.2e-06 27.3 0.0 4.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF563 PF04577.14 EIM89077.1 - 9e-08 32.5 0.0 2.3e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Helitron_like_N PF14214.6 EIM89078.1 - 3.6e-05 24.1 0.0 5.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Queuosine_synth PF02547.15 EIM89080.1 - 0.032 13.3 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein F-box PF00646.33 EIM89081.1 - 0.033 14.1 0.0 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box PF00646.33 EIM89083.1 - 0.07 13.0 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 F-box domain TPT PF03151.16 EIM89086.1 - 9e-23 81.0 19.7 1.1e-22 80.7 19.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family TMEM238 PF15125.6 EIM89086.1 - 0.4 10.9 7.1 1.5 9.1 7.1 2.1 1 0 0 1 1 1 0 TMEM238 protein family LSM PF01423.22 EIM89087.1 - 1.8e-15 56.4 0.1 2.2e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain zf-MYND PF01753.18 EIM89088.1 - 6.9e-07 29.3 16.2 1.3e-06 28.3 16.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM89088.1 - 0.12 12.8 8.1 0.24 11.7 8.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding AAA_12 PF13087.6 EIM89090.1 - 9.1e-39 133.1 0.0 2e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EIM89090.1 - 5.5e-34 117.4 4.7 2.2e-09 37.8 0.0 6.2 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EIM89090.1 - 6.9e-23 81.8 0.0 6.9e-23 81.8 0.0 6.4 6 0 0 6 6 6 1 AAA domain AAA_19 PF13245.6 EIM89090.1 - 3.9e-15 56.5 0.0 2e-07 31.5 0.0 5.3 4 2 1 5 5 5 3 AAA domain AAA_30 PF13604.6 EIM89090.1 - 1.3e-12 47.8 14.9 0.00012 21.8 0.0 5.6 6 0 0 6 6 5 3 AAA domain AAA_lid_6 PF17866.1 EIM89090.1 - 3.2e-12 46.4 6.9 0.00023 21.3 0.1 4.3 4 0 0 4 4 3 2 AAA lid domain Viral_helicase1 PF01443.18 EIM89090.1 - 1.9e-09 37.6 0.2 0.13 12.0 0.0 5.9 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 EIM89090.1 - 3.1e-08 33.7 3.3 0.1 12.6 0.0 4.7 6 0 0 6 6 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM89090.1 - 1.4e-07 31.9 8.6 1.5 9.1 0.1 7.8 6 3 0 7 7 7 2 AAA domain Mg_chelatase PF01078.21 EIM89090.1 - 1.6e-07 30.9 0.1 0.51 9.7 0.0 4.3 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EIM89090.1 - 5.9e-06 26.1 0.8 3.2 7.4 0.2 5.1 4 1 0 4 4 4 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EIM89090.1 - 8.3e-06 26.2 0.1 2.4 8.6 0.0 4.7 4 0 0 4 4 4 2 RNA helicase DUF2075 PF09848.9 EIM89090.1 - 8.4e-06 25.3 3.0 0.0021 17.3 0.0 5.3 6 0 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EIM89090.1 - 1.5e-05 24.8 0.2 3.5 7.3 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein ResIII PF04851.15 EIM89090.1 - 0.00034 20.7 3.4 0.016 15.3 0.0 4.9 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EIM89090.1 - 0.0014 18.2 0.4 5.1 6.6 0.1 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region PhoH PF02562.16 EIM89090.1 - 0.0023 17.4 1.1 2.7 7.4 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein AAA_24 PF13479.6 EIM89090.1 - 0.0025 17.6 10.5 4.4 7.0 0.1 5.7 5 1 0 5 5 5 1 AAA domain AAA_16 PF13191.6 EIM89090.1 - 0.0028 18.1 10.6 1.7 9.0 0.0 4.8 4 0 0 4 4 3 2 AAA ATPase domain Sigma54_activ_2 PF14532.6 EIM89090.1 - 0.005 17.0 0.0 8.9 6.4 0.0 4.0 4 0 0 4 4 4 0 Sigma-54 interaction domain ABC_tran PF00005.27 EIM89090.1 - 0.0059 17.1 0.2 31 5.1 0.0 4.6 3 0 0 3 3 3 0 ABC transporter CbiA PF01656.23 EIM89090.1 - 0.033 14.2 2.3 30 4.7 0.0 4.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 EIM89090.1 - 0.034 13.5 3.3 8.6 5.6 0.1 3.8 3 1 0 3 3 3 0 KaiC Helicase_RecD PF05127.14 EIM89090.1 - 0.039 13.8 0.1 2.7 7.8 0.0 3.4 3 0 0 3 3 2 0 Helicase RsgA_GTPase PF03193.16 EIM89090.1 - 0.082 12.8 0.4 12 5.7 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 EIM89090.1 - 0.19 12.2 15.9 2.2 8.8 0.0 5.3 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.6 EIM89090.1 - 0.43 10.1 9.8 2 7.9 0.0 4.0 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 EIM89090.1 - 4.9 7.3 18.3 3.1 8.0 0.1 4.8 5 0 0 5 5 3 0 AAA domain Transp_cyt_pur PF02133.15 EIM89091.1 - 2.3e-105 352.9 37.9 1.4e-67 228.4 27.4 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin SAYSvFN PF10260.9 EIM89091.1 - 0.27 11.2 0.1 0.27 11.2 0.1 3.6 4 1 0 4 4 4 0 Uncharacterized conserved domain (SAYSvFN) DUF2052 PF09747.9 EIM89092.1 - 1.9 8.6 5.1 3.3 7.8 5.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) HJURP_mid PF12346.8 EIM89092.1 - 4.7 7.7 11.0 0.66 10.5 3.6 2.5 3 0 0 3 3 3 0 Holliday junction recognition protein-associated repeat ATP-synt_E PF05680.12 EIM89092.1 - 6 7.3 9.9 1.4 9.3 3.1 2.5 2 0 0 2 2 2 0 ATP synthase E chain SOBP PF15279.6 EIM89092.1 - 6.9 7.2 16.6 2 9.0 13.6 1.5 1 1 0 1 1 1 0 Sine oculis-binding protein Pkinase PF00069.25 EIM89093.1 - 1.1e-44 152.8 0.0 1.5e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89093.1 - 8e-27 94.1 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EIM89093.1 - 0.00022 20.4 0.0 0.00022 20.4 0.0 1.4 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EIM89093.1 - 0.019 14.9 0.2 0.088 12.7 0.2 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM89093.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EF-hand_7 PF13499.6 EIM89093.1 - 0.19 12.2 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair PDT PF00800.18 EIM89094.1 - 1.7e-48 164.8 0.0 2.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ELYS PF13934.6 EIM89095.1 - 5.7e-37 127.8 0.1 6.7e-37 127.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly PITH PF06201.13 EIM89096.1 - 1.7e-32 112.7 0.0 2.1e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_S5_C PF03719.15 EIM89097.1 - 1e-18 66.5 0.0 9.2e-18 63.5 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EIM89097.1 - 1.7e-15 56.7 0.3 1.7e-15 56.7 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain YcaO PF02624.16 EIM89097.1 - 0.045 13.0 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding NUP PF06516.11 EIM89098.1 - 4.5e-126 420.3 0.0 5.1e-126 420.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DUF273 PF03314.14 EIM89098.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 p450 PF00067.22 EIM89101.1 - 2.6e-75 253.9 0.0 5.1e-75 253.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NTP_transf_8 PF12281.8 EIM89101.1 - 0.17 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase F-box-like PF12937.7 EIM89102.1 - 0.0018 18.1 0.1 0.0044 16.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM89102.1 - 0.0024 17.7 0.2 0.0057 16.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 EIM89103.1 - 3e-19 69.2 29.5 3e-19 69.2 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec23_trunk PF04811.15 EIM89104.1 - 8.2e-73 244.9 0.0 1.3e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EIM89104.1 - 4.1e-24 84.4 0.3 1.3e-23 82.8 0.3 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EIM89104.1 - 1.5e-16 60.1 5.2 1.3e-15 57.2 6.5 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EIM89104.1 - 5.3e-16 59.1 0.0 1.2e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EIM89104.1 - 1.6e-09 37.5 0.0 3.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 EIM89104.1 - 3.3e-06 27.1 0.2 3.3e-06 27.1 0.2 1.8 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 EIM89104.1 - 0.0026 17.1 0.4 0.005 16.2 0.4 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3458_C PF17432.2 EIM89104.1 - 0.01 15.2 0.3 0.015 14.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats VWA_2 PF13519.6 EIM89104.1 - 0.11 13.1 0.9 0.47 11.1 0.1 2.6 2 1 0 2 2 2 0 von Willebrand factor type A domain Peptidase_M20 PF01546.28 EIM89105.1 - 3.4e-25 89.0 0.1 4.6e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM89105.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM89105.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 DUF5046 PF16465.5 EIM89105.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) Thaumatin PF00314.17 EIM89106.1 - 4.4e-44 150.7 12.7 6.8e-44 150.1 12.7 1.3 1 0 0 1 1 1 1 Thaumatin family CPW_WPC PF09717.10 EIM89106.1 - 0.03 15.3 0.2 13 6.8 0.0 3.1 2 1 1 3 3 3 0 Plasmodium falciparum domain of unknown function (CPW_WPC) SKG6 PF08693.10 EIM89106.1 - 0.049 13.1 0.1 0.13 11.7 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4381 PF14316.6 EIM89106.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) adh_short_C2 PF13561.6 EIM89107.1 - 2.3e-54 184.4 0.0 2.7e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM89107.1 - 3.6e-50 170.2 0.0 5.4e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM89107.1 - 2e-17 63.7 0.2 2.8e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM89107.1 - 0.00023 20.7 0.0 0.00041 19.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EIM89107.1 - 0.0087 15.2 0.1 0.086 11.9 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EIM89107.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_5 PF08323.11 EIM89107.1 - 0.021 14.5 0.0 0.18 11.5 0.0 2.2 2 1 1 3 3 3 0 Starch synthase catalytic domain ADH_N PF08240.12 EIM89108.1 - 5.1e-28 97.1 1.7 5.6e-28 97.0 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM89108.1 - 1.4e-22 80.1 0.0 2.8e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM89108.1 - 4.9e-11 42.5 0.1 7.4e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIM89108.1 - 4.7e-05 24.5 0.0 0.0001 23.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIM89108.1 - 0.00064 19.1 0.1 0.00064 19.1 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EIM89108.1 - 0.0021 17.7 0.1 0.029 13.9 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 EIM89108.1 - 0.0037 16.6 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EIM89108.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 EIM89108.1 - 0.03 13.4 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_25 PF13649.6 EIM89108.1 - 0.033 14.9 0.4 0.11 13.2 0.2 2.1 2 2 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EIM89108.1 - 0.11 13.2 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EIM89108.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein YdfZ PF14001.6 EIM89108.1 - 0.28 11.6 2.1 0.77 10.2 0.0 2.6 3 0 0 3 3 3 0 YdfZ protein Peptidase_S41 PF03572.18 EIM89109.1 - 2.4e-05 24.0 0.0 6.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 adh_short PF00106.25 EIM89110.1 - 5.7e-47 159.7 0.0 7.2e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89110.1 - 1.1e-29 103.6 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM89110.1 - 1.4e-06 27.9 0.0 2.6e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EIM89110.1 - 0.003 17.0 0.0 0.0048 16.3 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 EIM89110.1 - 0.046 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 EIM89110.1 - 0.087 12.7 0.1 0.19 11.6 0.1 1.7 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 EIM89110.1 - 0.16 11.4 0.1 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase OPT PF03169.15 EIM89111.1 - 3.2e-91 306.9 43.2 3.6e-91 306.7 43.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.25 EIM89112.1 - 3.3e-30 105.0 0.0 5.1e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89112.1 - 1.1e-23 84.0 0.0 2.6e-23 82.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89112.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 EIM89112.1 - 0.035 14.7 0.1 2.9 8.5 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ubiquitin PF00240.23 EIM89113.1 - 1.9e-14 53.1 0.0 3.1e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 EIM89113.1 - 4.3e-08 33.6 0.9 6.6e-08 33.0 0.9 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD PF11976.8 EIM89113.1 - 2.9e-05 23.8 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ndufs5 PF10200.9 EIM89114.1 - 9.1e-06 25.8 0.7 1.1e-05 25.6 0.7 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 EIM89114.1 - 0.00015 21.7 1.8 0.00023 21.1 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EIM89114.1 - 0.0021 18.2 2.6 0.0028 17.7 1.3 1.8 1 1 1 2 2 2 2 CHCH domain PADR1 PF08063.12 EIM89114.1 - 0.015 15.1 4.6 1.2 9.0 0.8 2.6 2 1 1 3 3 3 0 PADR1 (NUC008) domain NDUF_B7 PF05676.13 EIM89114.1 - 0.03 14.1 2.1 0.045 13.5 2.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3128 PF11326.8 EIM89114.1 - 0.076 13.4 5.8 0.46 10.9 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) PX PF00787.24 EIM89116.1 - 9.5e-19 67.5 0.0 2.2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 EIM89116.1 - 4e-16 59.2 0.4 5e-14 52.3 0.9 2.1 2 0 0 2 2 2 2 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 EIM89116.1 - 0.00024 20.7 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain EST1 PF10374.9 EIM89116.1 - 0.063 13.9 0.4 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 Telomerase activating protein Est1 NUP PF06516.11 EIM89117.1 - 3.1e-126 420.8 0.0 3.6e-126 420.6 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DUF424 PF04242.13 EIM89117.1 - 0.13 12.5 0.1 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Aldo_ket_red PF00248.21 EIM89119.1 - 9e-42 143.3 0.2 4e-40 137.8 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Oxidored_FMN PF00724.20 EIM89120.1 - 2e-31 109.5 0.0 3.5e-28 98.9 0.0 2.7 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family NUP PF06516.11 EIM89121.1 - 5.7e-122 406.8 0.0 6.6e-122 406.6 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) NUP PF06516.11 EIM89122.1 - 3.5e-130 433.8 0.1 4.2e-130 433.6 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Hyccin PF09790.9 EIM89123.1 - 0.026 13.6 1.1 1.6 7.7 0.1 2.7 3 0 0 3 3 3 0 Hyccin Pro-kuma_activ PF09286.11 EIM89124.1 - 2.5e-37 128.3 0.0 5.1e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM89124.1 - 5.4e-05 22.6 0.3 5.4e-05 22.6 0.3 1.5 2 0 0 2 2 2 1 Subtilase family Trans_coact PF16805.5 EIM89124.1 - 0.088 12.9 0.5 0.23 11.6 0.5 1.6 1 0 0 1 1 1 0 Phage late-transcription coactivator PIG-L PF02585.17 EIM89125.1 - 1.8e-17 64.2 0.0 1.7e-16 61.1 0.0 2.0 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase TFIIE_alpha PF02002.17 EIM89126.1 - 5.3e-18 64.8 0.3 8.8e-18 64.1 0.3 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 EIM89126.1 - 6.9e-06 26.3 0.0 2.5e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 EIM89126.1 - 0.00011 21.6 0.8 0.00027 20.4 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding ADK_lid PF05191.14 EIM89126.1 - 0.014 15.3 0.4 0.036 14.0 0.4 1.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid HTH_Crp_2 PF13545.6 EIM89126.1 - 0.039 13.9 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EIM89126.1 - 0.1 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator zf_UBZ PF18439.1 EIM89126.1 - 0.1 12.2 0.5 0.59 9.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Bul1_N PF04425.12 EIM89126.1 - 0.11 11.2 0.0 0.26 10.0 0.0 1.5 1 0 0 1 1 1 0 Bul1 N terminus zf-C2H2_6 PF13912.6 EIM89126.1 - 0.38 10.8 3.1 0.38 10.8 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EIM89126.1 - 0.55 11.2 4.8 1.4 10.0 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EIM89126.1 - 1.5 9.4 5.2 0.51 10.9 0.2 2.7 3 0 0 3 3 2 0 Zinc finger, C2H2 type Acetyltransf_7 PF13508.7 EIM89127.1 - 0.00052 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM89127.1 - 0.00098 19.3 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EIM89127.1 - 0.0074 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase SpoIIIAC PF06686.11 EIM89129.1 - 0.2 11.9 1.1 18 5.6 1.7 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family CMD PF02627.20 EIM89130.1 - 8.3e-07 29.0 0.1 1.7e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family LRR_6 PF13516.6 EIM89131.1 - 8.4 6.7 16.2 3.8 7.8 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeat DUF1770 PF08589.10 EIM89133.1 - 0.045 14.7 0.1 0.045 14.7 0.1 2.3 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1770) adh_short PF00106.25 EIM89134.1 - 1.3e-28 99.8 0.0 2.7e-28 98.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89134.1 - 2e-23 83.2 0.0 5.2e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89134.1 - 1.8e-06 28.0 0.1 3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM89134.1 - 0.0011 18.1 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CMD PF02627.20 EIM89135.1 - 3.5e-09 36.6 0.0 1.5e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF3455 PF11937.8 EIM89136.1 - 2.7e-26 92.9 0.0 3.5e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3455 PF11937.8 EIM89137.1 - 2.7e-29 102.6 0.0 3.5e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Pup PF05639.11 EIM89138.1 - 0.05 14.5 0.1 0.67 10.9 0.1 2.3 2 0 0 2 2 2 0 Pup-like protein DUF2009 PF09418.10 EIM89138.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Val_tRNA-synt_C PF10458.9 EIM89138.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Rep_fac-A_3 PF08661.11 EIM89139.1 - 9.1e-19 67.8 0.0 1.1e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 UQ_con PF00179.26 EIM89141.1 - 5.4e-53 178.4 0.0 6e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EIM89141.1 - 0.0053 17.0 0.0 0.006 16.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EIM89141.1 - 0.015 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EIM89141.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Nup96 PF12110.8 EIM89144.1 - 1.8e-90 303.0 0.0 2.6e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 MFS_1 PF07690.16 EIM89145.1 - 8.1e-22 77.6 27.0 8.1e-22 77.6 27.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HpcH_HpaI PF03328.14 EIM89146.1 - 4.3e-29 101.2 0.2 7.4e-29 100.5 0.1 1.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 EIM89146.1 - 0.00035 19.6 0.1 0.0013 17.7 0.1 1.8 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain TraH_2 PF06871.11 EIM89146.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 TraH_2 Bac_luciferase PF00296.20 EIM89146.1 - 0.06 12.8 0.1 0.09 12.2 0.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF2909 PF11137.8 EIM89146.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) MFS_1 PF07690.16 EIM89147.1 - 1.6e-38 132.6 70.5 3.2e-34 118.4 50.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM89147.1 - 3.1e-07 29.6 13.7 3.1e-07 29.6 13.7 4.1 4 1 0 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.6 EIM89147.1 - 0.0084 14.7 34.4 0.037 12.6 3.0 4.7 2 1 1 4 4 4 4 MFS/sugar transport protein LIM PF00412.22 EIM89148.1 - 1.6e-23 82.7 24.4 5.7e-11 42.5 4.9 4.3 4 0 0 4 4 4 4 LIM domain Coatomer_WDAD PF04053.14 EIM89149.1 - 1.7e-137 459.2 0.0 3.9e-137 457.9 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EIM89149.1 - 3.2e-110 368.7 0.0 4.3e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EIM89149.1 - 4.8e-46 153.8 7.4 8.9e-09 35.9 0.6 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89149.1 - 5.4e-12 45.9 0.2 0.001 19.3 0.0 5.6 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM89149.1 - 0.0045 15.7 2.7 3.6 6.1 1.2 3.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TPR_14 PF13428.6 EIM89149.1 - 5.3 8.1 6.9 2.9e+02 2.7 0.8 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat XPG_I PF00867.18 EIM89150.1 - 4.1e-15 55.9 0.0 1.6e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EIM89150.1 - 6e-06 26.7 0.0 1.1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EIM89150.1 - 0.0081 16.7 0.1 0.032 14.8 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold CLTH PF10607.9 EIM89151.1 - 2.8e-34 118.2 0.1 4.7e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EIM89151.1 - 0.018 15.0 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger NBP1 PF08537.10 EIM89151.1 - 0.059 12.8 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 U-box PF04564.15 EIM89151.1 - 0.086 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 U-box domain Phasin_2 PF09361.10 EIM89151.1 - 0.09 13.1 1.5 16 5.8 0.3 2.4 2 0 0 2 2 2 0 Phasin protein Bacillus_HBL PF05791.11 EIM89151.1 - 0.16 11.8 1.0 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PIG-S PF10510.9 EIM89154.1 - 2.7e-118 396.0 12.7 1.8e-117 393.3 12.7 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF5372 PF17342.2 EIM89154.1 - 0.075 13.5 0.0 0.49 10.8 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5372) BTB PF00651.31 EIM89156.1 - 0.17 12.1 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Ras PF00071.22 EIM89157.1 - 6.2e-10 38.9 0.0 8.8e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Ras family NAC PF01849.18 EIM89158.1 - 7e-23 80.4 0.1 1.2e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain Acetyltransf_1 PF00583.25 EIM89159.1 - 4e-15 56.1 0.0 5.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM89159.1 - 2.3e-06 27.9 0.0 3.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM89159.1 - 6.4e-06 26.1 0.0 7.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM89159.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EIM89159.1 - 0.012 16.3 0.0 0.016 15.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIM89159.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cofilin_ADF PF00241.20 EIM89160.1 - 9.1e-26 90.0 0.2 1e-25 89.9 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Neugrin PF06413.11 EIM89161.1 - 1.6e-12 47.9 0.1 1.9e-12 47.7 0.1 1.0 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EIM89161.1 - 7.9e-06 26.1 0.0 8.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 p450 PF00067.22 EIM89162.1 - 6.4e-28 97.7 0.0 1.9e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 HlyIII PF03006.20 EIM89163.1 - 7.6e-56 189.3 18.1 9.3e-56 189.0 18.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Rotamase_3 PF13616.6 EIM89164.1 - 2.7e-18 66.6 0.0 5.7e-18 65.5 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EIM89164.1 - 2.4e-16 60.4 0.8 3.8e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EIM89164.1 - 0.00046 21.0 2.6 0.00088 20.1 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain CDP-OH_P_transf PF01066.21 EIM89165.1 - 0.083 13.7 1.9 0.39 11.5 1.9 2.3 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase CDP-OH_P_transf PF01066.21 EIM89166.1 - 2.6 8.9 6.5 1 10.2 1.8 2.8 1 1 1 2 2 2 0 CDP-alcohol phosphatidyltransferase AA_permease PF00324.21 EIM89167.1 - 3.1e-119 398.7 41.2 3.8e-119 398.4 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM89167.1 - 1.1e-30 106.8 42.9 1.9e-30 106.1 42.9 1.3 1 1 0 1 1 1 1 Amino acid permease DAO PF01266.24 EIM89168.1 - 1.1e-38 133.8 0.2 1.3e-38 133.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM89168.1 - 0.00077 19.7 0.0 0.0035 17.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EIM89168.1 - 0.00077 18.8 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM89168.1 - 0.0012 18.2 0.1 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EIM89168.1 - 0.0029 16.5 0.1 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 MCRA family Thi4 PF01946.17 EIM89168.1 - 0.0039 16.5 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EIM89168.1 - 0.065 13.8 0.1 5 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tyrosinase PF00264.20 EIM89169.1 - 2.7e-20 73.6 8.0 1.7e-19 71.0 8.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Epimerase PF01370.21 EIM89171.1 - 7.1e-07 28.9 0.0 9.9e-06 25.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM89171.1 - 2.2e-06 27.7 0.1 5.9e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EIM89171.1 - 7.4e-06 25.7 0.2 1.2e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EIM89171.1 - 1.3e-05 24.4 0.0 2.3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM89171.1 - 0.016 14.3 0.0 0.043 13.0 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 EIM89171.1 - 0.18 10.9 0.0 0.83 8.7 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain DUF3042 PF11240.8 EIM89172.1 - 0.00068 19.6 0.2 0.0011 19.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3042) Serglycin PF04360.12 EIM89172.1 - 0.0051 16.8 0.9 0.0058 16.6 0.9 1.2 1 0 0 1 1 1 1 Serglycin Sporozoite_P67 PF05642.11 EIM89172.1 - 0.17 10.0 5.5 0.18 9.9 5.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MMR_HSR1 PF01926.23 EIM89174.1 - 3e-20 72.4 0.3 2.2e-16 59.9 0.1 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM89174.1 - 2.9e-08 33.4 0.3 2e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIM89174.1 - 7.7e-08 32.4 0.0 2.4e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EIM89174.1 - 0.00026 21.1 0.2 0.084 12.9 0.2 3.0 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EIM89174.1 - 0.0004 20.0 0.0 0.013 15.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EIM89174.1 - 0.0013 17.8 0.1 0.0026 16.8 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EIM89174.1 - 0.0056 17.1 0.3 0.089 13.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EIM89174.1 - 0.027 14.7 0.0 6 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EIM89174.1 - 0.12 12.0 0.1 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EIM89174.1 - 0.18 12.3 0.8 0.38 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Virul_Fac PF10139.9 EIM89174.1 - 0.22 9.7 0.0 0.33 9.1 0.0 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor PARP PF00644.20 EIM89175.1 - 8.3e-10 38.6 2.5 2e-08 34.1 0.4 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Ecl1 PF12855.7 EIM89175.1 - 0.00071 20.8 5.6 0.0016 19.6 5.6 1.7 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins Perm-CXXC PF15629.6 EIM89175.1 - 0.061 13.6 1.5 0.061 13.6 1.5 3.6 3 0 0 3 3 3 0 Permuted single zf-CXXC unit Thioredoxin_2 PF13098.6 EIM89175.1 - 1.2 9.6 5.6 2 8.9 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin-like domain RPAP2_Rtr1 PF04181.13 EIM89175.1 - 3.6 8.0 20.0 53 4.2 0.2 4.8 3 1 1 4 4 4 0 Rtr1/RPAP2 family Ras PF00071.22 EIM89176.1 - 1.7e-26 92.8 0.0 2.5e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM89176.1 - 0.00039 20.6 0.0 0.012 15.8 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EIM89176.1 - 0.002 18.1 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase ATPase PF06745.13 EIM89176.1 - 0.03 13.7 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 KaiC Imm63 PF15599.6 EIM89176.1 - 0.037 14.4 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 63 NB-ARC PF00931.22 EIM89176.1 - 0.078 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EIM89176.1 - 0.13 12.6 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain FAD_binding_2 PF00890.24 EIM89177.1 - 4.2e-83 279.7 2.6 4.8e-83 279.6 2.6 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM89177.1 - 1.5e-16 60.9 2.5 2.2e-16 60.4 2.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM89177.1 - 2.5e-09 37.2 0.1 9.9e-09 35.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM89177.1 - 2.9e-08 33.3 0.3 6.2e-08 32.2 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM89177.1 - 7.8e-06 25.5 5.3 6.6e-05 22.4 5.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM89177.1 - 1.4e-05 24.0 8.1 5.7e-05 22.0 0.4 2.8 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EIM89177.1 - 5.1e-05 22.7 0.1 9.5e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EIM89177.1 - 7.7e-05 21.9 3.2 0.0027 16.8 0.2 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 EIM89177.1 - 0.00046 19.5 2.1 0.0026 17.1 0.5 2.4 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 EIM89177.1 - 0.0014 17.9 2.7 0.0022 17.3 2.7 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EIM89177.1 - 0.0066 17.0 0.5 0.0066 17.0 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EIM89177.1 - 0.011 16.2 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 EIM89177.1 - 0.013 14.8 0.1 0.074 12.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EIM89177.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EIM89177.1 - 0.035 13.2 0.3 0.051 12.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein SPA PF08616.10 EIM89178.1 - 8.8e-35 119.1 0.0 1.5e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EIM89178.1 - 1.2e-20 74.4 0.3 8.1e-16 58.7 0.0 2.7 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EIM89178.1 - 7.9e-07 28.1 0.0 7e-05 21.7 0.0 3.4 3 1 1 4 4 4 1 Transport protein Avl9 Dioxygenase_C PF00775.21 EIM89179.1 - 7e-43 146.2 0.0 9.6e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EIM89179.1 - 1.1e-24 86.0 0.0 1.9e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EIM89179.1 - 3.7e-05 23.9 0.2 0.00011 22.4 0.1 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain MetallophosN PF16371.5 EIM89179.1 - 0.023 14.9 0.4 0.092 13.0 0.2 2.0 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase DUF4791 PF16039.5 EIM89182.1 - 0.16 11.5 2.3 0.26 10.8 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) LPG_synthase_TM PF03706.13 EIM89183.1 - 0.0081 15.7 6.5 0.0081 15.7 6.5 1.9 1 1 1 2 2 2 2 Lysylphosphatidylglycerol synthase TM region Acyl_transf_3 PF01757.22 EIM89183.1 - 0.022 13.8 7.6 0.011 14.8 4.6 1.8 1 1 1 2 2 2 0 Acyltransferase family RseC_MucC PF04246.12 EIM89183.1 - 4 7.4 5.9 1.8 8.6 2.2 1.9 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC zinc_ribbon_10 PF10058.9 EIM89186.1 - 2.4e-19 68.8 0.1 3.9e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 EIM89186.1 - 0.07 13.3 0.6 0.14 12.3 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 EIM89186.1 - 0.24 11.6 0.6 0.63 10.2 0.6 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like SDA1 PF05285.12 EIM89187.1 - 0.44 9.9 14.0 0.99 8.8 14.0 1.5 1 0 0 1 1 1 0 SDA1 TLP-20 PF06088.11 EIM89187.1 - 1.1 9.2 8.3 0.13 12.1 2.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4637 PF15470.6 EIM89187.1 - 3.1 7.5 10.9 7.2 6.3 10.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2052 PF09747.9 EIM89187.1 - 4.2 7.5 14.4 4.3 7.4 12.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Sterol_MT_C PF08498.10 EIM89188.1 - 0.16 12.3 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal RNase_PH PF01138.21 EIM89191.1 - 6.2e-16 59.1 0.1 1.1e-15 58.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EIM89191.1 - 6.9e-05 22.8 2.2 0.00042 20.3 0.1 3.0 2 2 1 3 3 3 1 3' exoribonuclease family, domain 2 DNApol_Exo PF18136.1 EIM89192.1 - 4e-100 334.6 0.1 7.4e-100 333.7 0.1 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EIM89192.1 - 2.6e-50 171.6 0.0 4.9e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Med8 PF10232.9 EIM89192.1 - 0.036 13.7 4.7 0.075 12.6 4.7 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1841 PF08897.11 EIM89192.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) ETX_MTX2 PF03318.13 EIM89192.1 - 0.24 11.2 0.1 0.45 10.2 0.1 1.4 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF572 PF04502.13 EIM89192.1 - 7.4 6.1 8.0 4.1 6.9 5.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) FAM220 PF15487.6 EIM89195.1 - 0.065 12.9 3.3 0.087 12.4 3.3 1.1 1 0 0 1 1 1 0 FAM220 family Rrp44_CSD1 PF17216.3 EIM89195.1 - 0.16 11.7 1.1 0.31 10.8 1.1 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain YL1 PF05764.13 EIM89195.1 - 0.19 11.8 6.4 0.28 11.3 6.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 EIM89195.1 - 0.25 9.9 6.6 0.31 9.6 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mucin PF01456.17 EIM89195.1 - 0.47 10.4 22.8 0.79 9.7 22.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Endomucin PF07010.12 EIM89195.1 - 0.74 9.7 15.9 1.1 9.2 15.9 1.1 1 0 0 1 1 1 0 Endomucin Dicty_REP PF05086.12 EIM89195.1 - 5.3 4.9 9.2 6.6 4.6 9.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3583 PF12126.8 EIM89196.1 - 1.3 8.4 5.0 2.2 7.7 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF3455 PF11937.8 EIM89200.1 - 5.5e-26 91.8 0.0 8.7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MMR_HSR1 PF01926.23 EIM89201.1 - 1.3e-11 44.6 0.0 2.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Herpes_UL47 PF03362.13 EIM89201.1 - 0.0005 19.0 0.1 0.00074 18.4 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus UL47 protein RsgA_GTPase PF03193.16 EIM89201.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EIM89201.1 - 0.0074 15.8 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EIM89201.1 - 0.013 15.9 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 EIM89201.1 - 0.025 13.7 0.2 0.057 12.5 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 EIM89201.1 - 0.047 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EIM89201.1 - 0.053 14.1 0.8 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EIM89201.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family IIGP PF05049.13 EIM89201.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 EIM89201.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EIM89201.1 - 0.13 12.3 1.5 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Dynamin family DUF3915 PF13054.6 EIM89202.1 - 0.058 13.4 7.0 0.13 12.2 7.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RR_TM4-6 PF06459.12 EIM89202.1 - 0.058 13.2 3.8 0.11 12.4 3.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 EIM89202.1 - 0.1 11.0 8.8 0.15 10.5 8.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Phage_Gp23 PF10669.9 EIM89202.1 - 0.99 9.7 7.0 1.7 9.0 7.0 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) TT_ORF1 PF02956.14 EIM89202.1 - 1.7 7.2 9.5 2.1 6.9 9.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 Cas_Csy4 PF09618.10 EIM89202.1 - 2.1 8.5 5.5 3.4 7.8 5.5 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) VIR_N PF15912.5 EIM89202.1 - 6.8 6.2 14.1 4.9 6.7 3.2 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Fungal_trans PF04082.18 EIM89205.1 - 2.5e-22 79.2 0.1 7.5e-22 77.6 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM89205.1 - 1.5e-09 37.9 12.1 2.7e-09 37.0 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EIM89205.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Glu_cyclase_2 PF05096.12 EIM89205.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine cyclotransferase DUF1604 PF07713.13 EIM89206.1 - 1.6e-08 34.3 0.4 1.9e-08 34.0 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) zf-C3HC4_3 PF13920.6 EIM89208.1 - 1.8e-11 43.7 5.5 1.6e-09 37.5 1.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM89208.1 - 0.00058 19.7 3.1 0.00092 19.0 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM89208.1 - 0.0013 18.6 4.7 0.0013 18.6 4.7 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EIM89208.1 - 0.0019 18.5 6.0 0.0054 17.0 1.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EIM89208.1 - 0.0053 16.7 2.1 0.07 13.1 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIM89208.1 - 0.78 9.8 5.6 13 6.0 0.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_L27A PF00828.19 EIM89209.1 - 4.8e-23 82.2 0.1 6.6e-23 81.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.6 EIM89210.1 - 5.2e-25 87.0 0.0 6.7e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EIM89210.1 - 1.5e-08 33.9 0.0 2.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 EIM89210.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal NMD3 PF04981.13 EIM89212.1 - 2.9e-81 272.5 0.8 3.8e-81 272.1 0.8 1.1 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 EIM89212.1 - 0.033 14.2 6.3 0.79 9.8 4.8 2.7 1 1 1 2 2 2 0 Double zinc ribbon NinF PF05810.12 EIM89212.1 - 0.073 12.9 1.8 0.15 11.9 0.4 2.2 2 0 0 2 2 2 0 NinF protein DUF35_N PF12172.8 EIM89212.1 - 0.18 11.7 8.8 1.2 9.1 0.5 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TT_ORF2 PF02957.15 EIM89212.1 - 0.43 11.5 0.1 0.43 11.5 0.1 2.8 1 1 1 2 2 2 0 TT viral ORF2 DPBB_1 PF03330.18 EIM89216.1 - 1.1e-07 32.0 0.3 2.9e-07 30.6 0.3 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM89216.1 - 0.045 13.6 0.1 0.07 13.0 0.1 1.4 1 1 0 1 1 1 0 Barwin family SKG6 PF08693.10 EIM89217.1 - 0.00081 18.8 6.2 0.0024 17.2 6.2 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 EIM89217.1 - 0.0057 16.4 0.1 0.0095 15.7 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EIM89217.1 - 0.053 14.4 0.0 0.087 13.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 EIM89218.1 - 6.3e-66 222.4 0.0 1.1e-65 221.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89218.1 - 1.7e-32 112.8 0.0 3.2e-32 111.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM89218.1 - 1.2e-05 25.4 0.0 3.3e-05 23.9 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM89218.1 - 0.03 13.3 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Lyase_8 PF02278.18 EIM89219.1 - 4.9e-59 199.9 8.7 8.5e-59 199.1 8.7 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 EIM89219.1 - 6.6e-14 51.6 0.1 1.1e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 EIM89219.1 - 8.4e-07 29.4 0.1 1.9e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain PPR_2 PF13041.6 EIM89220.1 - 6.8e-05 23.0 0.4 3.9 7.7 0.0 4.5 4 0 0 4 4 4 2 PPR repeat family PPR_long PF17177.4 EIM89220.1 - 0.0017 17.8 0.4 0.014 14.7 0.0 2.4 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EIM89220.1 - 0.031 14.5 3.4 17 5.9 0.0 4.7 5 0 0 5 5 5 0 PPR repeat SWIRM PF04433.17 EIM89221.1 - 4.3e-31 107.1 0.0 9.7e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EIM89221.1 - 1e-20 73.5 10.3 1e-20 73.5 10.3 1.9 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EIM89221.1 - 6.7e-11 42.2 0.7 1.4e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 EIM89221.1 - 3.5e-09 36.3 3.1 6.3e-09 35.5 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EIM89221.1 - 1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Zip PF02535.22 EIM89221.1 - 0.13 11.4 0.2 0.24 10.6 0.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C50 PF03568.17 EIM89222.1 - 4.7e-141 470.5 0.0 9.1e-141 469.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 EIM89222.1 - 5.1e-05 23.5 14.3 0.12 12.7 1.5 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM89222.1 - 0.00022 21.2 3.9 1.8 9.0 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM89222.1 - 0.011 16.0 2.3 0.34 11.2 0.1 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIM89222.1 - 0.012 15.6 0.1 37 4.7 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP-synt_DE PF00401.20 EIM89222.1 - 0.02 15.1 0.1 0.14 12.5 0.1 2.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TPR_1 PF00515.28 EIM89222.1 - 0.5 10.3 9.9 36 4.4 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rogdi_lz PF10259.9 EIM89222.1 - 0.6 9.5 8.8 0.46 9.9 2.9 3.3 2 2 2 4 4 4 0 Rogdi leucine zipper containing protein TPR_MalT PF17874.1 EIM89222.1 - 1.3 8.3 6.8 0.58 9.5 0.9 2.7 3 0 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 EIM89222.1 - 5.4 7.0 7.1 0.7 9.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DASH_Dam1 PF08653.10 EIM89223.1 - 4.7e-22 77.5 0.1 8e-22 76.8 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Hrs_helical PF12210.8 EIM89223.1 - 0.14 12.8 0.0 1.1e+02 3.5 0.0 3.3 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MRP-L46 PF11788.8 EIM89224.1 - 0.04 14.7 1.5 0.04 14.7 1.5 2.1 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 RNA_pol_N PF01194.17 EIM89225.1 - 4.3e-31 107.0 0.3 5.4e-31 106.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Mu-like_Com PF10122.9 EIM89225.1 - 0.062 12.8 1.0 0.18 11.3 0.1 2.0 1 1 1 2 2 2 0 Mu-like prophage protein Com MIOX PF05153.15 EIM89226.1 - 1.5e-125 417.7 1.2 2.5e-125 417.1 1.2 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EIM89226.1 - 0.0098 16.1 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 HD domain Speriolin_C PF15059.6 EIM89226.1 - 0.054 13.6 0.5 0.084 13.0 0.5 1.2 1 0 0 1 1 1 0 Speriolin C-terminus TFR_dimer PF04253.15 EIM89226.1 - 0.067 13.3 1.8 0.34 11.0 0.1 2.7 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain HAD PF12710.7 EIM89227.1 - 3.1e-20 73.4 0.0 4.2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EIM89227.1 - 1.1e-06 28.3 0.0 3.1e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 EIM89227.1 - 2.6e-05 24.6 0.2 0.0014 19.0 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EIM89227.1 - 0.00012 21.7 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 EIM89227.1 - 0.015 15.3 0.0 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 EIM89228.1 - 1.3e-05 25.4 1.8 0.0095 16.3 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM89228.1 - 0.00026 21.6 1.0 0.069 14.0 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-TFIIB PF13453.6 EIM89228.1 - 0.0058 15.9 1.1 0.011 15.0 1.1 1.5 1 0 0 1 1 1 1 Transcription factor zinc-finger zf-UBP PF02148.19 EIM89228.1 - 0.024 15.0 0.3 0.055 13.8 0.3 1.6 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_jaz PF12171.8 EIM89228.1 - 0.059 13.7 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EIM89228.1 - 0.11 12.3 0.0 8 6.3 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EIM89228.1 - 0.13 12.7 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CAP_N PF01213.19 EIM89228.1 - 0.55 9.7 6.0 0.82 9.1 6.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EIM89228.1 - 4.5 7.3 4.9 6.4 6.8 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PIP5K PF01504.18 EIM89229.1 - 4.7e-98 327.8 0.1 2.7e-97 325.3 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase HIT PF01230.23 EIM89230.1 - 3.3e-24 85.5 0.2 4.2e-24 85.1 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EIM89230.1 - 1e-13 51.7 0.1 1.4e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EIM89230.1 - 0.0054 16.6 0.3 0.01 15.7 0.3 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Peptidase_S9 PF00326.21 EIM89231.1 - 1.5e-29 103.0 0.0 2.9e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EIM89231.1 - 7.4e-08 32.0 0.0 7.3e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM89231.1 - 3.7e-05 23.5 0.1 0.00093 18.9 0.3 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EIM89231.1 - 0.0061 16.1 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EIM89231.1 - 0.009 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Glyco_transf_24 PF18404.1 EIM89232.1 - 4.3e-143 475.5 1.4 6.5e-143 475.0 1.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EIM89232.1 - 4.3e-67 226.8 0.0 6.1e-61 206.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EIM89232.1 - 2e-49 168.0 0.0 6.3e-49 166.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EIM89232.1 - 1.8e-42 145.7 0.0 9.2e-39 133.6 0.2 3.5 3 0 0 3 3 3 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EIM89232.1 - 1.6e-38 131.2 0.0 3.2e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 EIM89232.1 - 4.1e-38 130.4 0.1 7.9e-37 126.2 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EIM89232.1 - 3.4e-05 23.5 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 adh_short PF00106.25 EIM89233.1 - 9.1e-22 77.5 0.0 1.2e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89233.1 - 1.4e-16 60.8 0.0 1.8e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89233.1 - 0.00017 21.5 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EIM89235.1 - 5.8e-39 133.6 0.0 8.3e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89235.1 - 9.8e-28 97.3 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EIM89235.1 - 1.3e-07 31.3 0.0 5.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EIM89235.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM89235.1 - 0.0035 17.3 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM89235.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1414 PF07208.11 EIM89235.1 - 0.047 13.7 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) SGL PF08450.12 EIM89236.1 - 3.8e-26 92.2 0.0 6.4e-26 91.4 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EIM89236.1 - 0.0038 17.3 0.0 0.021 14.9 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 EIM89236.1 - 0.066 13.4 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 Arylesterase SGL PF08450.12 EIM89237.1 - 9.4e-27 94.2 0.5 1.6e-26 93.4 0.5 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EIM89237.1 - 1.2e-05 25.3 0.1 0.00013 22.1 0.0 2.7 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 EIM89237.1 - 0.0048 17.1 0.1 0.026 14.7 0.1 2.2 1 1 0 1 1 1 1 Arylesterase CHAT PF12770.7 EIM89238.1 - 1.3e-25 90.4 0.1 3.7e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 CHAT domain TPR_4 PF07721.14 EIM89238.1 - 1.1 10.0 3.8 1 10.1 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Seryl_tRNA_N PF02403.22 EIM89239.1 - 4.5 7.6 8.5 10 6.4 8.5 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CNOT1_CAF1_bind PF16415.5 EIM89241.1 - 8e-74 247.8 2.2 4.4e-57 193.1 0.1 2.5 1 1 1 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EIM89241.1 - 7.1e-54 181.7 0.0 2.9e-53 179.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EIM89241.1 - 1.3e-53 181.0 0.0 2.3e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Cation_ATPase PF13246.6 EIM89241.1 - 1e-13 51.1 0.0 2.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) SpuA_C PF18033.1 EIM89241.1 - 0.095 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 SpuA C-terminal KDZ PF18758.1 EIM89243.1 - 1.1e-49 169.1 0.0 2e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 EIM89243.1 - 3.9e-14 53.0 1.1 6.8e-14 52.2 1.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 EIM89243.1 - 0.021 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases TBP PF00352.21 EIM89244.1 - 4.6e-37 125.8 0.3 9.7e-24 83.1 0.0 3.1 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) MULE PF10551.9 EIM89245.1 - 1.3e-10 41.6 0.0 4.2e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EIM89245.1 - 3.3e-06 26.6 0.3 6.3e-06 25.7 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger Pkinase PF00069.25 EIM89246.1 - 2.1e-29 102.7 0.0 2.5e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89246.1 - 4.9e-14 52.3 0.0 5.5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM89246.1 - 9.9e-06 24.6 0.0 1.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM89246.1 - 2.6e-05 24.3 0.0 0.027 14.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EIM89246.1 - 0.057 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 zf-RING_2 PF13639.6 EIM89247.1 - 5.7e-12 45.8 3.7 9.2e-12 45.1 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM89247.1 - 3e-09 36.6 2.9 4.9e-09 35.9 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIM89247.1 - 4.7e-08 33.2 6.6 1.4e-07 31.7 6.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EIM89247.1 - 7.3e-07 29.1 3.3 1.1e-06 28.4 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM89247.1 - 1.1e-06 28.5 2.3 1.7e-06 27.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM89247.1 - 4.9e-05 23.0 0.9 9.4e-05 22.1 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EIM89247.1 - 6.9e-05 22.6 1.9 0.00011 22.0 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM89247.1 - 0.0001 22.2 1.1 0.00021 21.3 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EIM89247.1 - 0.0013 18.8 1.0 0.0024 17.9 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EIM89247.1 - 0.004 16.8 2.5 0.0067 16.0 2.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EIM89247.1 - 0.012 15.8 2.5 0.023 14.9 2.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EIM89247.1 - 0.033 14.3 4.1 0.058 13.5 4.1 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EIM89247.1 - 0.17 11.7 2.5 0.32 10.9 2.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EIM89247.1 - 0.68 9.9 1.9 1.2 9.1 1.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EIM89247.1 - 0.95 9.3 2.3 1.5 8.6 2.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EIM89247.1 - 2.6 8.4 4.4 4.3 7.7 4.4 1.3 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.25 EIM89248.1 - 5.3e-29 101.4 0.0 8.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89248.1 - 2.6e-11 43.3 0.0 3.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM89248.1 - 9.1e-11 41.2 0.0 1.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM89248.1 - 0.00064 19.7 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM89248.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_10 PF13374.6 EIM89249.1 - 0.00043 20.1 5.1 0.88 9.5 0.2 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM89249.1 - 0.043 13.2 1.0 0.27 10.6 1.0 2.1 1 1 0 1 1 1 0 MalT-like TPR region CHAT PF12770.7 EIM89250.1 - 1.1e-25 90.7 0.0 2.4e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM89250.1 - 0.0017 18.2 11.9 0.061 13.2 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89250.1 - 1.1 10.3 9.0 14 6.8 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Cnd1 PF12717.7 EIM89251.1 - 1.8e-52 177.7 7.4 4.7e-48 163.3 0.3 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EIM89251.1 - 3e-43 147.5 1.1 1.2e-42 145.5 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term ENTH PF01417.20 EIM89251.1 - 0.0049 16.9 0.1 3.9 7.5 0.0 3.0 2 0 0 2 2 2 2 ENTH domain HEAT PF02985.22 EIM89251.1 - 0.015 15.5 0.6 0.71 10.3 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat OrfA PF17495.2 EIM89251.1 - 0.035 14.3 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Vpr-like OrfA RTP1_C1 PF10363.9 EIM89251.1 - 0.053 13.7 0.3 3.7 7.8 0.0 3.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EIM89251.1 - 0.076 12.2 0.7 0.89 8.7 0.4 2.5 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain YtzH PF14165.6 EIM89251.1 - 0.24 11.8 1.4 1.8 9.0 0.1 3.0 2 1 1 3 3 3 0 YtzH-like protein DUF1295 PF06966.12 EIM89252.1 - 2.7e-48 164.5 4.3 4.2e-48 163.9 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EIM89252.1 - 0.00052 20.4 0.0 0.0023 18.3 0.0 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EIM89252.1 - 0.025 14.6 2.4 0.17 11.8 2.4 2.3 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EIM89252.1 - 0.67 10.4 3.9 0.44 11.0 0.7 2.3 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family E1-E2_ATPase PF00122.20 EIM89254.1 - 1.7e-48 164.5 0.1 1.7e-48 164.5 0.1 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EIM89254.1 - 3.4e-17 63.4 3.3 3.4e-17 63.4 3.3 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIM89254.1 - 7.6e-14 51.2 0.1 2e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIM89254.1 - 0.00033 20.5 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIM89254.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Pkinase PF00069.25 EIM89255.1 - 9e-67 225.2 0.0 1.6e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89255.1 - 2.2e-39 135.3 0.0 4.1e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EIM89255.1 - 1.5e-33 114.8 2.0 9.5e-19 67.4 0.1 3.0 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EIM89255.1 - 1.9e-06 27.4 2.9 3.1e-06 26.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EIM89255.1 - 0.026 13.5 0.0 0.062 12.2 0.0 1.7 1 0 0 1 1 1 0 Haspin like kinase domain DUF4520 PF15016.6 EIM89255.1 - 0.028 14.5 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Baculo_E25 PF05274.11 EIM89255.1 - 0.034 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 Cnd3 PF12719.7 EIM89256.1 - 4.2e-81 272.4 1.8 1e-79 267.8 1.0 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EIM89256.1 - 2e-08 34.5 4.4 0.00014 22.2 0.1 4.6 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 EIM89256.1 - 2.3e-07 30.5 2.5 0.78 10.2 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EIM89256.1 - 2.6e-07 30.8 2.2 0.014 15.4 0.1 4.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EIM89256.1 - 0.078 12.5 0.2 0.42 10.1 0.0 2.3 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 EIM89256.1 - 0.11 13.0 0.3 1.1 9.9 0.1 3.0 3 0 0 3 3 3 0 HEAT-like repeat TINF2_N PF14973.6 EIM89256.1 - 1.7 9.0 5.8 1.1 9.6 1.1 3.0 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Cnd1 PF12717.7 EIM89257.1 - 4.4e-52 176.4 4.3 6.5e-48 162.8 0.1 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EIM89257.1 - 2.1e-38 131.8 0.1 7.8e-38 129.9 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 EIM89257.1 - 0.00038 19.2 9.8 0.15 10.6 0.6 4.2 3 2 2 5 5 5 3 Adaptin N terminal region HEAT PF02985.22 EIM89257.1 - 0.00077 19.5 3.8 0.95 9.9 0.2 5.6 7 0 0 7 7 7 1 HEAT repeat RTP1_C1 PF10363.9 EIM89257.1 - 0.00084 19.5 2.3 6.8 6.9 0.1 4.4 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 tRNA_NucTran2_2 PF13735.6 EIM89257.1 - 0.017 15.1 0.3 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative TIP120 PF08623.10 EIM89257.1 - 5.4 6.7 8.5 1.5 8.5 0.0 3.8 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) Transket_pyr PF02779.24 EIM89258.1 - 1.3e-60 204.1 0.0 2e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EIM89258.1 - 3.6e-46 156.6 0.0 6.3e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EIM89258.1 - 2.7e-45 154.6 0.0 6e-45 153.5 0.0 1.6 1 1 0 1 1 1 1 Dehydrogenase E1 component DUF3338 PF11819.8 EIM89258.1 - 0.15 12.1 0.4 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) DBINO PF13892.6 EIM89258.1 - 0.16 12.4 0.9 0.31 11.4 0.9 1.4 1 0 0 1 1 1 0 DNA-binding domain Response_reg PF00072.24 EIM89259.1 - 8.7e-24 83.9 0.1 1.5e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain MAPEG PF01124.18 EIM89260.1 - 2.4e-15 56.6 0.9 2.7e-15 56.4 0.9 1.1 1 0 0 1 1 1 1 MAPEG family Apt1 PF10351.9 EIM89261.1 - 7 5.4 6.1 10 4.8 6.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMC_N PF02463.19 EIM89266.1 - 1.2e-61 208.0 0.0 2e-61 207.2 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIM89266.1 - 1.4e-29 102.8 0.2 4.5e-29 101.1 0.2 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EIM89266.1 - 7e-16 58.9 0.2 1.4e-06 28.4 0.1 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIM89266.1 - 1.8e-10 41.6 11.6 1.8e-10 41.6 11.6 6.2 2 2 2 4 4 1 1 AAA domain AAA_29 PF13555.6 EIM89266.1 - 1.3e-06 28.0 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EIM89266.1 - 1.9e-06 27.9 5.8 1.9e-06 27.9 5.8 4.6 2 2 0 3 3 2 1 AAA ATPase domain SbcCD_C PF13558.6 EIM89266.1 - 0.0034 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit TolA_bind_tri PF16331.5 EIM89266.1 - 0.0044 17.1 3.4 0.0044 17.1 3.4 6.3 6 2 1 7 7 5 1 TolA binding protein trimerisation NPV_P10 PF05531.12 EIM89266.1 - 0.031 14.7 24.7 0.05 14.1 0.4 6.6 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 EIM89266.1 - 0.22 12.0 0.0 0.22 12.0 0.0 5.8 4 3 0 4 4 3 0 ABC transporter Synaptonemal_3 PF15191.6 EIM89266.1 - 1.1 9.1 10.0 23 4.9 3.2 4.3 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 ApoC-I PF04691.12 EIM89266.1 - 3.2 7.8 7.4 1.3 9.0 2.4 3.2 3 0 0 3 3 2 0 Apolipoprotein C-I (ApoC-1) Tnp_22_trimer PF17489.2 EIM89266.1 - 4.7 7.3 12.1 34 4.5 0.0 3.6 2 1 0 2 2 2 0 L1 transposable element trimerization domain AAA_13 PF13166.6 EIM89266.1 - 4.9 5.7 72.7 0.18 10.4 0.3 6.5 3 2 0 5 5 4 0 AAA domain Glutaredoxin2_C PF04399.13 EIM89266.1 - 7.7 6.4 9.9 38 4.1 0.0 5.0 4 0 0 4 4 4 0 Glutaredoxin 2, C terminal domain Acylphosphatase PF00708.18 EIM89266.1 - 9.1 6.8 7.6 32 5.0 0.1 4.1 3 0 0 3 3 3 0 Acylphosphatase FlaC_arch PF05377.11 EIM89266.1 - 9.1 6.8 32.8 6.5 7.2 0.2 7.5 6 2 3 9 9 8 0 Flagella accessory protein C (FlaC) Dimer_Tnp_hAT PF05699.14 EIM89267.1 - 8e-08 32.0 0.2 1e-07 31.6 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF818 PF05677.12 EIM89267.1 - 0.14 11.1 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PLU-1 PF08429.11 EIM89268.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein Aldo_ket_red PF00248.21 EIM89269.1 - 1.1e-39 136.4 0.0 1.3e-38 132.9 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM89270.1 - 1.6e-42 145.7 0.0 1.6e-40 139.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NADHdh_A3 PF14987.6 EIM89277.1 - 0.17 12.2 1.1 0.35 11.2 1.1 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 MAPEG PF01124.18 EIM89278.1 - 1.1e-06 28.5 0.7 2e-06 27.8 0.7 1.3 1 0 0 1 1 1 1 MAPEG family DUF2158 PF09926.9 EIM89281.1 - 0.11 12.2 0.1 9.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) LAT PF15234.6 EIM89281.1 - 3.5 7.3 6.6 19 4.9 2.3 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells Ribosomal_S13_N PF08069.12 EIM89282.1 - 5e-31 106.5 0.1 1.1e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EIM89282.1 - 2.2e-15 56.6 0.4 3.3e-15 56.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EIM89282.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 'Paired box' domain Ribosomal_S6e PF01092.19 EIM89283.1 - 8.4e-56 187.3 0.0 1.5e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e MKLP1_Arf_bdg PF16540.5 EIM89283.1 - 0.19 11.8 3.8 0.28 11.3 1.3 2.4 3 0 0 3 3 3 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Alpha_L_fucos PF01120.17 EIM89284.1 - 5.2e-77 259.6 4.4 8.5e-77 259.0 4.4 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 EIM89284.1 - 0.0029 18.1 0.1 0.018 15.6 0.1 2.3 1 1 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 EIM89284.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Ydr279_N PF17745.1 EIM89284.1 - 0.12 12.7 0.5 24 5.3 0.0 2.8 3 0 0 3 3 3 0 Ydr279p protein triple barrel domain HMG_box PF00505.19 EIM89286.1 - 5.4e-14 52.4 0.1 7.3e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM89286.1 - 0.00049 20.6 0.0 0.00075 20.0 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain Glycohydro_20b2 PF14845.6 EIM89286.1 - 0.021 15.5 0.0 0.022 15.4 0.0 1.0 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like MATalpha_HMGbox PF04769.12 EIM89286.1 - 0.028 13.7 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF3712 PF12505.8 EIM89288.1 - 2.4e-164 538.3 65.3 2.3e-25 89.3 0.1 13.6 12 0 0 12 12 12 10 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EIM89288.1 - 5.8e-14 52.5 16.3 0.046 14.3 0.0 9.6 8 0 0 8 8 8 5 Late embryogenesis abundant protein Chlorosome_CsmC PF11098.8 EIM89288.1 - 5.4e-06 26.4 18.0 1.8e-05 24.7 18.0 1.9 1 0 0 1 1 1 1 Chlorosome envelope protein C tRNA-synt_1d PF00750.19 EIM89289.1 - 9.4e-101 337.2 1.7 1.2e-100 336.8 1.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EIM89289.1 - 1.6e-20 73.4 0.0 3.6e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain UPF0220 PF05255.11 EIM89291.1 - 6.6e-56 188.4 0.0 7.8e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) dsrm PF00035.26 EIM89292.1 - 8.8e-05 23.1 0.0 0.0002 22.0 0.0 1.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif But2 PF09792.9 EIM89294.1 - 0.0015 18.9 0.0 0.011 16.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 EIM89295.1 - 3.8e-17 62.8 3.9 1.3e-16 61.1 3.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) RRM_1 PF00076.22 EIM89297.1 - 1.4e-12 47.2 0.0 2.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EIM89297.1 - 8.4e-06 26.2 0.1 1.6e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DPBB_1 PF03330.18 EIM89298.1 - 1.5e-05 25.2 0.0 2.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM89298.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Barwin family HLH PF00010.26 EIM89300.1 - 5.7e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DPBB_1 PF03330.18 EIM89302.1 - 0.0002 21.6 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM89302.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 Barwin family FAD_binding_3 PF01494.19 EIM89303.1 - 5.5e-80 269.2 0.0 7.7e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM89303.1 - 8.1e-08 32.2 0.1 5.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM89303.1 - 3.1e-07 29.9 1.3 0.0037 16.5 0.0 3.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM89303.1 - 1.8e-05 25.2 0.1 0.075 13.6 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM89303.1 - 0.0001 21.7 0.1 0.001 18.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM89303.1 - 0.00026 20.2 0.6 0.002 17.3 0.0 2.1 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EIM89303.1 - 0.00097 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM89303.1 - 0.0042 16.4 0.0 0.0083 15.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EIM89303.1 - 0.0073 15.1 0.2 0.036 12.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EIM89303.1 - 0.054 12.8 0.2 0.18 11.1 0.2 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIM89303.1 - 0.096 11.5 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EIM89303.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SesA PF17107.5 EIM89303.1 - 0.12 12.6 0.3 1.8 8.8 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MFS_1 PF07690.16 EIM89304.1 - 5e-21 75.0 43.7 2.6e-17 62.8 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EIM89305.1 - 3e-17 62.6 35.0 8.1e-10 38.1 6.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.9 EIM89305.1 - 0.029 14.8 2.5 4.6 7.7 0.1 3.4 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase CDC27 PF09507.10 EIM89306.1 - 0.038 13.4 11.3 0.044 13.2 11.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3381 PF11861.8 EIM89306.1 - 3 7.6 18.7 0.69 9.7 11.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Trypan_PARP PF05887.11 EIM89306.1 - 3.4 7.6 10.7 4.9 7.1 10.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) 6PF2K PF01591.18 EIM89310.1 - 2e-62 210.4 0.0 3.2e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EIM89310.1 - 9.9e-24 84.1 0.0 2.5e-23 82.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EIM89310.1 - 7.2e-05 23.0 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIM89310.1 - 0.00089 18.8 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF816 PF05674.12 EIM89310.1 - 0.15 12.0 0.8 0.26 11.2 0.8 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Hydrolase_4 PF12146.8 EIM89311.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM89311.1 - 0.027 15.1 0.0 0.032 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.24 EIM89312.1 - 1.7e-69 234.9 23.7 2.9e-69 234.1 23.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM89312.1 - 3.7e-27 95.2 51.4 1.5e-24 86.6 30.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM89312.1 - 2.4e-05 23.0 4.4 4.7e-05 22.0 4.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0182 PF03699.13 EIM89312.1 - 3.4 5.7 4.4 0.75 7.9 0.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) F-box-like PF12937.7 EIM89313.1 - 0.002 17.9 0.1 0.0052 16.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF3762 PF12591.8 EIM89313.1 - 0.048 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) LRR_4 PF12799.7 EIM89313.1 - 0.1 13.1 0.5 19 5.8 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EIM89316.1 - 0.00051 19.9 1.9 0.00081 19.2 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EIM89319.1 - 0.00047 20.0 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM89319.1 - 0.0025 17.7 0.1 0.0086 15.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EIM89319.1 - 0.046 13.6 0.2 0.099 12.5 0.2 1.6 1 0 0 1 1 1 0 F-box MFS_2 PF13347.6 EIM89320.1 - 0.0022 16.6 9.0 0.0022 16.6 9.0 2.0 1 1 0 2 2 2 1 MFS/sugar transport protein Bac_export_2 PF01312.19 EIM89320.1 - 2 7.5 7.5 3.1 6.9 7.5 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Insulin_TMD PF17870.1 EIM89321.1 - 0.6 10.2 8.5 1.3 9.1 0.7 2.9 2 1 1 3 3 3 0 Insulin receptor trans-membrane segment PEN-2 PF10251.9 EIM89321.1 - 0.72 10.3 4.9 0.16 12.4 0.7 1.9 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase sCache_3_3 PF17202.4 EIM89322.1 - 0.076 13.4 0.2 0.09 13.2 0.2 1.3 1 1 0 1 1 1 0 Single cache domain 3 Ifi-6-16 PF06140.13 EIM89324.1 - 1.1e-06 28.4 22.8 1.1e-06 28.4 22.8 1.7 2 1 0 2 2 2 1 Interferon-induced 6-16 family NmrA PF05368.13 EIM89325.1 - 4.1e-20 72.3 0.0 5.4e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM89325.1 - 3.3e-15 56.5 0.0 1.9e-14 54.0 0.0 2.2 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIM89325.1 - 0.011 14.8 0.1 0.07 12.1 0.1 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Endotoxin_C2 PF18449.1 EIM89325.1 - 0.075 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Delta endotoxin Band_7 PF01145.25 EIM89326.1 - 2.8e-06 27.5 0.0 2.8e-06 27.5 0.0 2.8 3 1 0 3 3 3 1 SPFH domain / Band 7 family Arginase PF00491.21 EIM89327.1 - 9.5e-88 294.3 0.0 1.2e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EIM89327.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.18 EIM89328.1 - 9.2e-54 181.4 20.4 1.3e-27 96.5 8.4 2.4 2 0 0 2 2 2 2 MatE Sugar_tr PF00083.24 EIM89329.1 - 5.4e-99 332.1 17.7 6.2e-99 331.9 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM89329.1 - 1.1e-25 90.3 63.3 1.5e-20 73.4 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EIM89329.1 - 0.0051 15.2 0.9 0.0051 15.2 0.9 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EIM89330.1 - 1.9e-19 69.8 25.2 3.5e-19 69.0 25.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EIM89330.1 - 0.00038 19.9 3.3 0.00038 19.9 3.3 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Hydantoinase_B PF02538.14 EIM89331.1 - 9.6e-195 647.9 4.7 1.3e-194 647.5 4.7 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EIM89331.1 - 6e-101 337.5 0.8 2.2e-100 335.7 0.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EIM89331.1 - 4.9e-59 199.0 2.9 1.2e-57 194.5 0.0 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Aa_trans PF01490.18 EIM89333.1 - 2.3e-38 132.0 38.8 5e-38 130.9 38.7 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CHAT PF12770.7 EIM89334.1 - 8.7e-27 94.3 0.0 2.3e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 CHAT domain AbiEi_3 PF11459.8 EIM89334.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system DUF1863 PF08937.11 EIM89335.1 - 0.052 13.9 0.0 0.07 13.4 0.0 1.4 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) CHAT PF12770.7 EIM89336.1 - 0.0038 16.7 0.0 0.004 16.6 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Goodbye PF17109.5 EIM89337.1 - 1.1e-24 87.2 0.1 1.3e-23 83.7 0.0 2.5 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain APG6_N PF17675.1 EIM89337.1 - 0.086 13.4 1.1 0.13 12.8 0.1 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Ank_4 PF13637.6 EIM89338.1 - 9.6e-23 80.3 2.9 3e-07 30.9 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM89338.1 - 3e-19 69.4 2.6 4.1e-11 43.3 0.4 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EIM89338.1 - 2.7e-17 62.3 3.4 0.0018 18.7 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EIM89338.1 - 6.1e-17 60.0 0.9 0.0027 18.1 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EIM89338.1 - 4.5e-15 55.5 1.2 4e-07 30.2 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) FLgD_tudor PF13861.6 EIM89338.1 - 0.00014 22.1 0.0 0.24 11.6 0.0 2.7 1 1 1 2 2 2 2 FlgD Tudor-like domain YajC PF02699.15 EIM89338.1 - 0.0038 17.1 2.3 1.4 8.9 0.1 3.5 2 1 2 4 4 4 1 Preprotein translocase subunit HMG_box PF00505.19 EIM89339.1 - 1e-08 35.5 0.2 3.3e-08 33.8 0.2 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box CENP-B_dimeris PF09026.10 EIM89342.1 - 0.2 12.1 3.5 0.3 11.5 3.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_C14 PF00656.22 EIM89343.1 - 9.8e-24 84.7 0.0 1.9e-23 83.7 0.0 1.5 1 1 0 1 1 1 1 Caspase domain HhH-GPD PF00730.25 EIM89344.1 - 4.4e-11 43.2 0.0 7.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EIM89344.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Peptidase_C14 PF00656.22 EIM89345.1 - 5.2e-24 85.6 0.1 8.3e-24 84.9 0.1 1.5 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EIM89345.1 - 0.14 12.1 0.2 1.9 8.4 0.0 2.6 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain ABC_membrane PF00664.23 EIM89346.1 - 1.6e-51 175.6 31.2 3.1e-28 99.2 11.1 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 EIM89346.1 - 1.4e-42 145.4 0.0 4.6e-25 88.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM89346.1 - 3.5e-11 42.9 3.1 0.0058 16.1 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIM89346.1 - 7.7e-07 29.6 0.4 0.034 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EIM89346.1 - 1.6e-06 28.8 0.8 0.00038 21.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIM89346.1 - 1.9e-06 27.9 4.6 0.048 13.5 0.2 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM89346.1 - 6.3e-06 25.8 1.2 0.012 15.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EIM89346.1 - 2.2e-05 23.6 0.1 0.0029 16.7 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EIM89346.1 - 2.3e-05 24.1 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EIM89346.1 - 0.00034 20.9 0.2 0.75 10.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EIM89346.1 - 0.0014 18.7 0.4 0.5 10.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 EIM89346.1 - 0.002 18.3 0.7 0.068 13.3 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EIM89346.1 - 0.0063 16.4 0.1 4.8 7.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 EIM89346.1 - 0.0078 15.7 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EIM89346.1 - 0.022 14.1 0.7 3.3 7.0 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 EIM89346.1 - 0.029 14.3 0.2 1.1 9.2 0.0 3.0 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EIM89346.1 - 0.031 14.3 0.5 29 4.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIM89346.1 - 0.04 13.6 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 EIM89346.1 - 0.044 12.7 0.5 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 EIM89346.1 - 0.053 14.1 0.1 9.1 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 EIM89346.1 - 0.054 12.3 0.2 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 EIM89346.1 - 0.083 12.9 0.4 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 EIM89346.1 - 0.13 11.7 1.3 3.4 7.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.19 EIM89346.1 - 0.14 11.7 3.0 0.45 10.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 EIM89346.1 - 0.16 11.7 0.4 23 4.7 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 EIM89346.1 - 0.3 11.0 1.4 6.8 6.6 0.1 2.7 3 0 0 3 3 3 0 NACHT domain HMG_box PF00505.19 EIM89350.1 - 7e-10 39.2 3.9 9.1e-10 38.8 3.9 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM89350.1 - 3e-08 34.1 2.9 4e-08 33.7 2.9 1.2 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.14 EIM89350.1 - 0.1 12.6 3.0 0.14 12.2 3.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DDE_3 PF13358.6 EIM89353.1 - 2.5e-05 24.1 0.3 0.00098 18.9 0.0 2.7 2 1 0 2 2 2 1 DDE superfamily endonuclease Exonuc_V_gamma PF04257.14 EIM89353.1 - 0.13 10.5 0.0 0.24 9.6 0.0 1.3 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit zf-C2H2_10 PF16588.5 EIM89354.1 - 0.3 10.9 7.9 0.4 10.5 4.6 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger RVT_1 PF00078.27 EIM89356.1 - 7.3e-07 28.9 0.0 8.5e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 EIM89358.1 - 0.00011 22.4 0.2 0.00021 21.5 0.0 1.5 2 0 0 2 2 2 1 RNase H ABC_membrane PF00664.23 EIM89359.1 - 1.2e-46 159.5 27.3 1.8e-28 100.0 5.2 3.8 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 EIM89359.1 - 9.1e-43 146.1 0.0 6.3e-25 88.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM89359.1 - 2.6e-12 46.7 2.3 0.00041 19.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIM89359.1 - 5.4e-07 30.3 1.2 0.00013 22.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EIM89359.1 - 2.5e-06 27.1 0.4 0.011 15.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EIM89359.1 - 8.9e-06 26.2 0.1 0.21 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 EIM89359.1 - 1.4e-05 25.1 7.9 0.063 13.1 0.2 4.2 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EIM89359.1 - 3.5e-05 23.0 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EIM89359.1 - 7e-05 22.5 0.0 0.2 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EIM89359.1 - 0.0017 17.9 0.1 0.94 9.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EIM89359.1 - 0.0021 18.3 0.5 2.9 8.2 0.1 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EIM89359.1 - 0.0056 16.8 0.2 0.37 10.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM89359.1 - 0.0063 16.4 0.0 3.6 7.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Adeno_IVa2 PF02456.15 EIM89359.1 - 0.0098 14.7 0.5 0.12 11.2 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF87 PF01935.17 EIM89359.1 - 0.012 15.7 1.7 0.051 13.7 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase_2 PF01637.18 EIM89359.1 - 0.015 15.2 0.2 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EIM89359.1 - 0.017 15.1 0.2 26 4.8 0.1 4.1 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIM89359.1 - 0.024 14.4 0.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EIM89359.1 - 0.035 13.4 0.4 8.8 5.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EIM89359.1 - 0.041 12.8 0.5 4 6.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 EIM89359.1 - 0.051 13.0 0.5 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Roc PF08477.13 EIM89359.1 - 0.054 13.7 0.1 28 5.0 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EIM89359.1 - 0.076 12.6 1.8 0.65 9.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 EIM89359.1 - 0.081 12.7 0.9 9.7 5.9 0.0 3.0 3 1 0 3 3 2 0 DEAD/DEAH box helicase NACHT PF05729.12 EIM89359.1 - 0.098 12.6 0.9 6.5 6.6 0.1 3.0 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 EIM89359.1 - 0.11 12.2 0.1 4.2 7.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EIM89359.1 - 0.13 12.8 0.1 28 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EIM89359.1 - 0.15 11.5 0.8 16 4.8 0.2 3.3 2 1 1 3 3 3 0 PhoH-like protein GvpD PF07088.11 EIM89359.1 - 0.18 10.4 0.5 0.42 9.2 0.0 1.7 2 0 0 2 2 2 0 GvpD gas vesicle protein AAA_24 PF13479.6 EIM89359.1 - 0.28 10.9 0.6 28 4.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EIM89359.1 - 0.45 10.4 1.6 21 4.9 0.0 2.8 3 0 0 3 3 2 0 NTPase Peptidase_M28 PF04389.17 EIM89360.1 - 9.6e-27 94.0 0.7 2.2e-26 92.8 0.7 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIM89360.1 - 5.4e-07 29.5 0.0 6.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Phosphoesterase PF04185.14 EIM89360.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoesterase family Peptidase_M42 PF05343.14 EIM89360.1 - 0.018 14.1 0.0 0.042 12.9 0.0 1.6 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase CAS_CSE1 PF03378.15 EIM89360.1 - 0.26 9.8 0.0 0.46 8.9 0.0 1.3 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Peptidase_C14 PF00656.22 EIM89361.1 - 0.042 13.8 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Caspase domain DUF1148 PF06618.11 EIM89361.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Peptidase_C14 PF00656.22 EIM89362.1 - 2.7e-23 83.2 0.0 3.2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain TPR_10 PF13374.6 EIM89363.1 - 1.2e-37 126.7 12.9 1.8e-12 46.7 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89363.1 - 5.3e-34 116.4 4.6 6.3e-13 48.8 0.2 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EIM89363.1 - 3.5e-09 36.0 6.1 0.0053 16.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM89363.1 - 6.5e-07 29.0 3.0 1.2e-06 28.2 3.0 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 EIM89363.1 - 2.3e-06 27.3 1.5 3.9 7.8 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM89363.1 - 2.6e-05 23.8 1.2 0.84 9.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 EIM89363.1 - 8.5e-05 22.5 0.0 0.00026 20.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 EIM89363.1 - 8.8e-05 22.6 3.3 1.1 9.8 0.0 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM89363.1 - 9.3e-05 22.9 0.2 19 5.9 0.0 5.2 2 1 3 5 5 5 0 Tetratricopeptide repeat NB-ARC PF00931.22 EIM89363.1 - 0.0011 18.2 0.2 0.016 14.4 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain TPR_4 PF07721.14 EIM89363.1 - 0.0063 17.0 10.4 1.5 9.6 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM89363.1 - 0.01 16.0 0.5 7.2 7.1 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat CutA1 PF03091.15 EIM89363.1 - 0.034 14.0 0.6 18 5.2 0.1 3.4 1 1 2 3 3 3 0 CutA1 divalent ion tolerance protein AAA_16 PF13191.6 EIM89363.1 - 0.062 13.7 0.2 0.49 10.8 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain Patatin PF01734.22 EIM89364.1 - 6.1e-25 88.6 0.0 9.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Polyketide_cyc2 PF10604.9 EIM89368.1 - 4.2e-09 36.8 0.2 8e-08 32.7 0.2 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EIM89368.1 - 4.6e-06 26.9 0.0 6.4e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_C14 PF00656.22 EIM89369.1 - 2.6e-37 129.1 0.0 3.9e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 EIM89370.1 - 9.3e-38 130.6 0.0 1.6e-37 129.8 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Ecm29 PF13001.7 EIM89370.1 - 0.16 10.7 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Proteasome stabiliser Peptidase_C14 PF00656.22 EIM89371.1 - 3.1e-22 79.7 0.0 3.4e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EIM89371.1 - 0.096 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 EIM89372.1 - 1.1e-12 48.5 0.1 1.4e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 Caspase domain 2OG-FeII_Oxy_3 PF13640.6 EIM89373.1 - 1.4e-09 38.7 0.1 3.8e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 EIM89375.1 - 3.6e-08 33.2 0.3 1e-07 31.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EIM89377.1 - 5.6e-18 65.0 9.0 2.2e-07 31.5 0.6 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 EIM89377.1 - 2.9e-06 27.3 0.0 0.19 11.8 0.0 3.6 3 1 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 EIM89377.1 - 6.3e-06 26.4 0.0 0.15 12.4 0.0 4.0 3 3 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM89377.1 - 0.068 12.1 0.1 18 4.2 0.0 3.2 1 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-MYND PF01753.18 EIM89379.1 - 4.4e-06 26.7 11.6 8.8e-06 25.7 11.6 1.5 1 0 0 1 1 1 1 MYND finger OrfB_IS605 PF01385.19 EIM89379.1 - 0.1 12.8 0.4 0.21 11.8 0.4 1.5 1 0 0 1 1 1 0 Probable transposase OmpH PF03938.14 EIM89379.1 - 0.35 11.2 4.2 0.64 10.4 4.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-C6H2 PF15801.5 EIM89379.1 - 0.41 11.0 8.3 0.92 9.9 8.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Complex1_51K PF01512.17 EIM89380.1 - 8.6e-48 162.1 0.0 1.3e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EIM89380.1 - 1.1e-30 105.6 1.1 2.1e-30 104.6 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EIM89380.1 - 3.2e-08 33.3 0.0 8.6e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EIM89380.1 - 0.11 12.6 0.3 0.19 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) NAD_binding_4 PF07993.12 EIM89381.1 - 1.4e-30 106.3 0.0 2.9e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM89381.1 - 3.7e-22 78.5 0.0 5.4e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM89381.1 - 7.8e-12 45.2 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM89381.1 - 1.7e-05 25.1 0.0 6.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 EIM89381.1 - 0.0011 18.9 0.0 0.0033 17.4 0.0 1.8 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EIM89381.1 - 0.0075 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Peptidase_M20 PF01546.28 EIM89384.1 - 6.7e-31 107.6 0.0 1.1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM89384.1 - 5.2e-13 48.9 0.0 8.6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM89384.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Abhydrolase_1 PF00561.20 EIM89385.1 - 1.3e-20 74.1 0.5 5.6e-19 68.8 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM89385.1 - 1.9e-13 50.3 0.0 2.2e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM89385.1 - 4.3e-09 37.3 1.5 6.3e-09 36.8 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3530 PF12048.8 EIM89385.1 - 0.00077 19.0 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_5 PF12695.7 EIM89385.1 - 0.0089 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EIM89385.1 - 0.052 13.4 0.0 0.082 12.8 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 EIM89385.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 EIM89385.1 - 0.081 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EIM89386.1 - 1.1e-16 61.2 0.0 6.7e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM89386.1 - 1.6e-14 53.8 0.0 2.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM89386.1 - 7.1e-13 49.7 0.0 8.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EIM89386.1 - 0.00056 20.1 0.0 0.00087 19.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Transp_inhibit PF18791.1 EIM89386.1 - 0.0081 15.6 0.6 0.029 13.9 0.2 2.0 2 0 0 2 2 2 1 Transport inhibitor response 1 protein domain Peptidase_S9 PF00326.21 EIM89386.1 - 0.064 12.7 0.0 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family SAM_adeno_trans PF01887.16 EIM89386.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Peptidase_S15 PF02129.18 EIM89386.1 - 0.14 11.8 0.2 0.46 10.0 0.2 1.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EIM89386.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EIM89386.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 EIM89387.1 - 6.8e-48 163.0 0.0 8e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM89387.1 - 3.5e-16 60.5 2.2 4.5e-16 60.1 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM89387.1 - 4.4e-09 36.3 0.3 2.2e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM89387.1 - 4.4e-07 29.6 0.4 0.0007 19.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EIM89387.1 - 0.0011 18.5 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 EIM89387.1 - 0.0015 17.3 0.1 0.0046 15.7 0.1 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF900 PF05990.12 EIM89387.1 - 0.0075 15.8 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) Say1_Mug180 PF10340.9 EIM89387.1 - 0.0098 14.8 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 EIM89387.1 - 0.018 14.0 0.0 0.056 12.3 0.0 1.8 2 1 0 2 2 2 0 Chlorophyllase enzyme DUF3089 PF11288.8 EIM89387.1 - 0.057 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LIDHydrolase PF10230.9 EIM89387.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LCAT PF02450.15 EIM89387.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase SUR7 PF06687.12 EIM89388.1 - 2.1e-09 37.3 14.1 2.9e-08 33.6 13.6 2.2 1 1 0 1 1 1 1 SUR7/PalI family SUR7 PF06687.12 EIM89389.1 - 4.8e-14 52.5 7.7 9.3e-14 51.6 7.6 1.5 1 1 0 1 1 1 1 SUR7/PalI family zf-MYND PF01753.18 EIM89390.1 - 4.2e-11 42.7 9.2 4.2e-11 42.7 9.2 2.3 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EIM89390.1 - 2.4 8.3 10.4 0.13 12.4 3.8 2.3 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ubiquitin PF00240.23 EIM89391.1 - 3.4e-19 68.4 0.1 4.2e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EIM89391.1 - 6.6e-06 25.9 0.2 8.9e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIM89391.1 - 0.00022 21.6 0.0 0.00088 19.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EIM89391.1 - 0.0075 16.8 0.0 0.01 16.4 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain SH3BGR PF04908.15 EIM89391.1 - 0.058 13.6 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ubiquitin_4 PF18036.1 EIM89391.1 - 0.071 13.2 0.1 2.8 8.0 0.1 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EIM89391.1 - 0.14 12.5 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain zf-CCHC PF00098.23 EIM89392.1 - 0.0016 18.4 3.1 0.0045 17.0 3.1 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EIM89392.1 - 0.0031 17.7 0.4 0.0089 16.3 0.4 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DUF5053 PF16476.5 EIM89393.1 - 0.042 13.5 0.2 0.095 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) PAF PF15715.5 EIM89394.1 - 2.2 8.8 9.0 4.6 7.8 9.0 1.4 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Abhydrolase_1 PF00561.20 EIM89396.1 - 1.4e-12 47.8 0.0 1e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM89396.1 - 2.5e-06 28.3 0.0 2.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM89396.1 - 2.7e-06 26.8 0.0 5.9e-06 25.7 0.0 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF3530 PF12048.8 EIM89396.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) APH PF01636.23 EIM89397.1 - 9.2e-16 58.5 0.5 2.6e-15 57.0 0.5 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM89397.1 - 0.00063 19.4 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EIM89397.1 - 0.22 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF2207 PF09972.9 EIM89398.1 - 0.027 13.3 0.1 0.035 12.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AA_permease PF00324.21 EIM89399.1 - 1.5e-120 403.1 42.9 1.7e-120 402.9 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM89399.1 - 8.2e-35 120.4 46.7 1e-34 120.1 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4516 PF14990.6 EIM89399.1 - 0.12 12.1 1.6 0.4 10.4 1.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DAHP_synth_2 PF01474.16 EIM89401.1 - 5.8e-196 651.2 0.0 6.5e-196 651.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF2031 PF09592.10 EIM89403.1 - 0.033 13.7 0.4 4.3 6.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2031) CHAT PF12770.7 EIM89404.1 - 5.2e-36 124.5 0.2 7.4e-36 124.0 0.2 1.2 1 0 0 1 1 1 1 CHAT domain TPR_2 PF07719.17 EIM89404.1 - 1e-28 97.1 0.0 1.8 8.9 0.0 16.2 17 1 0 17 17 17 4 Tetratricopeptide repeat TPR_8 PF13181.6 EIM89404.1 - 5.1e-24 82.4 0.0 3.6 8.0 0.0 16.3 18 0 0 18 18 17 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM89404.1 - 1.5e-19 69.4 0.0 0.91 9.3 0.0 14.0 16 0 0 16 16 16 1 TPR repeat TPR_14 PF13428.6 EIM89404.1 - 2.1e-17 62.3 13.2 2.7 9.0 0.0 14.4 16 0 0 16 16 13 2 Tetratricopeptide repeat CRISPR_Cse2 PF09485.10 EIM89404.1 - 3.5e-12 47.0 22.6 2.8 8.5 0.1 14.4 3 2 13 16 16 16 3 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_10 PF13374.6 EIM89404.1 - 2.8e-11 42.9 16.8 0.98 9.4 0.0 14.8 19 0 0 19 19 19 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM89404.1 - 1.7e-07 30.7 0.0 85 3.2 0.0 10.3 10 0 0 10 10 10 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EIM89404.1 - 3.6e-07 30.1 0.0 28 4.9 0.0 9.7 13 0 0 13 13 11 0 Exonuclease VII small subunit TPR_16 PF13432.6 EIM89404.1 - 0.00016 22.3 7.1 53 4.6 0.0 8.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Erythro-docking PF09277.11 EIM89404.1 - 0.0031 17.4 19.3 0.59 10.1 0.0 7.7 6 1 2 8 8 7 2 Erythronolide synthase, docking Wtap PF17098.5 EIM89404.1 - 0.0078 16.2 0.1 7 6.6 0.0 4.1 5 0 0 5 5 4 1 WTAP/Mum2p family DUF4164 PF13747.6 EIM89404.1 - 0.014 15.7 10.5 79 3.6 0.0 8.4 11 0 0 11 11 9 0 Domain of unknown function (DUF4164) PHD_3 PF13922.6 EIM89404.1 - 0.019 15.3 0.2 52 4.3 0.0 6.3 9 0 0 9 9 8 0 PHD domain of transcriptional enhancer, Asx HSBP1 PF06825.12 EIM89404.1 - 0.041 13.8 13.7 3.2 7.7 0.0 7.0 8 0 0 8 8 8 0 Heat shock factor binding protein 1 SMBP PF16785.5 EIM89404.1 - 0.11 12.7 19.7 29 4.9 0.0 10.7 14 1 0 14 14 12 0 Small metal-binding protein Vps5 PF09325.10 EIM89404.1 - 0.12 11.9 0.0 64 3.0 0.0 4.5 4 1 1 5 5 5 0 Vps5 C terminal like SPRY PF00622.28 EIM89406.1 - 0.04 14.0 0.0 0.061 13.4 0.0 1.2 1 1 0 1 1 1 0 SPRY domain LPMO_10 PF03067.15 EIM89408.1 - 6.7e-11 43.2 2.5 8.5e-11 42.9 2.5 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading N_BRCA1_IG PF16158.5 EIM89408.1 - 0.0033 18.1 0.0 0.0084 16.8 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene Glyco_hydro_61 PF03443.14 EIM89408.1 - 0.015 15.3 0.5 0.19 11.6 0.5 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 zf-MYND PF01753.18 EIM89409.1 - 1.5e-08 34.6 9.5 3e-08 33.6 9.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM89409.1 - 0.08 13.3 7.8 0.16 12.3 7.8 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-C2H2 PF00096.26 EIM89410.1 - 2e-05 24.8 1.2 0.022 15.2 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM89410.1 - 0.00016 22.2 1.4 0.14 13.1 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM89410.1 - 0.15 12.4 0.3 0.15 12.4 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EIM89410.1 - 0.25 11.6 2.2 1.1 9.6 2.2 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding SUIM_assoc PF16619.5 EIM89410.1 - 1.5 8.9 9.1 1.1 9.3 0.5 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 adh_short PF00106.25 EIM89414.1 - 4.5e-40 137.2 0.0 6.3e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89414.1 - 1.7e-29 103.0 0.0 2.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89414.1 - 1.7e-07 31.3 0.0 8.6e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EIM89414.1 - 0.00053 19.9 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding GidB PF02527.15 EIM89414.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Eno-Rase_NADH_b PF12242.8 EIM89414.1 - 0.0027 17.4 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 EIM89414.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family pP_pnuc_1 PF18165.1 EIM89414.1 - 0.18 11.7 0.0 0.84 9.5 0.0 1.9 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease NAD_binding_10 PF13460.6 EIM89415.1 - 1.3e-12 48.0 0.0 2.7e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM89415.1 - 0.046 13.3 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family AmoC PF04896.12 EIM89415.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C CxC7 PF18866.1 EIM89415.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases GPHR_N PF12537.8 EIM89417.1 - 0.14 12.3 0.8 0.14 12.3 0.8 1.9 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF3450 PF11932.8 EIM89419.1 - 0.036 13.4 20.5 0.037 13.3 2.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) PH_RBD PF12068.8 EIM89419.1 - 0.16 11.4 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Rab-binding domain (RBD) Aa_trans PF01490.18 EIM89422.1 - 3.7e-27 95.1 25.3 4.2e-26 91.6 25.3 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Snapin_Pallidin PF14712.6 EIM89426.1 - 0.18 12.2 3.8 2.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Conotoxin PF02950.17 EIM89427.1 - 0.0086 17.1 1.0 0.028 15.4 1.6 1.6 2 0 0 2 2 2 1 Conotoxin Toxin_19 PF08088.12 EIM89427.1 - 0.042 14.0 4.2 0.06 13.5 4.2 1.2 1 0 0 1 1 1 0 Conotoxin I-superfamily Toxin_12 PF07740.12 EIM89427.1 - 0.048 14.3 5.5 0.071 13.8 5.5 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin Conotoxin_I2 PF17557.2 EIM89427.1 - 0.052 13.7 6.7 0.078 13.1 6.7 1.3 1 0 0 1 1 1 0 I2-superfamily conotoxins Pollen_allerg_2 PF01620.16 EIM89427.1 - 0.21 11.8 0.3 0.21 11.8 0.3 1.4 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) Gly-zipper_Omp PF13488.6 EIM89429.1 - 0.014 15.4 0.3 0.022 14.7 0.3 1.3 1 0 0 1 1 1 0 Glycine zipper zf-MYND PF01753.18 EIM89431.1 - 3.5e-07 30.2 15.0 8.2e-07 29.0 15.0 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM89431.1 - 0.51 10.7 11.4 1.1 9.7 11.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 EIM89432.1 - 9.1e-08 31.9 0.1 2.1e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like Trypan_PARP PF05887.11 EIM89435.1 - 0.0044 17.0 6.8 0.0044 17.0 6.8 4.5 3 1 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) Sec34 PF04136.15 EIM89437.1 - 5e-12 46.0 0.1 5.7e-12 45.8 0.1 1.0 1 0 0 1 1 1 1 Sec34-like family Glyco_hydro_3_C PF01915.22 EIM89440.1 - 4.2e-46 157.5 0.0 6.1e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM89440.1 - 2.1e-28 99.6 0.0 3.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM89440.1 - 3.9e-11 42.9 0.0 7.6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cu-oxidase PF00394.22 EIM89441.1 - 6.8e-47 159.5 0.1 1.5e-43 148.7 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM89441.1 - 9.5e-37 125.8 5.9 1.4e-35 122.0 0.1 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM89441.1 - 4e-36 123.6 0.3 3.5e-35 120.6 0.3 2.6 3 0 0 3 3 3 1 Multicopper oxidase HNH_2 PF13391.6 EIM89442.1 - 3.3e-06 27.1 0.5 9.5e-06 25.7 0.2 2.0 2 0 0 2 2 2 1 HNH endonuclease ANXA2R PF15721.5 EIM89442.1 - 0.055 14.0 0.9 0.096 13.2 0.9 1.3 1 0 0 1 1 1 0 Annexin-2 receptor Ferric_reduct PF01794.19 EIM89442.1 - 0.076 13.1 0.2 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase like transmembrane component SRF-TF PF00319.18 EIM89445.1 - 2.1e-23 81.5 0.1 2.8e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MFS_1 PF07690.16 EIM89447.1 - 5.5e-29 101.2 25.3 5.5e-29 101.2 25.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM89447.1 - 1.2e-10 40.8 4.2 1.2e-10 40.8 4.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.32 EIM89449.1 - 4.5e-36 122.2 12.6 1.1e-07 32.4 0.0 5.3 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89449.1 - 5e-16 58.8 0.0 0.00062 20.0 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIM89449.1 - 5.3e-06 26.2 0.3 4 7.5 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EIM89449.1 - 0.0016 17.5 0.0 3.5 6.5 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 EIM89449.1 - 0.39 10.4 4.4 35 4.2 0.4 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3618 PF12277.8 EIM89451.1 - 0.0058 16.9 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) Plavaka PF18759.1 EIM89452.1 - 6.7e-37 127.4 0.0 9.5e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase BUD22 PF09073.10 EIM89454.1 - 6.1 6.1 25.8 8.2 5.6 25.8 1.1 1 0 0 1 1 1 0 BUD22 120_Rick_ant PF12574.8 EIM89455.1 - 0.049 12.8 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Carn_acyltransf PF00755.20 EIM89456.1 - 4.3e-207 689.4 0.0 2.8e-206 686.7 0.0 1.8 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 EIM89459.1 - 5.5e-30 104.5 0.1 6.1e-30 104.4 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CP12 PF02672.15 EIM89459.1 - 0.05 14.3 0.1 0.079 13.7 0.1 1.3 1 0 0 1 1 1 0 CP12 domain F-box-like PF12937.7 EIM89460.1 - 5.7 6.9 7.7 0.88 9.5 0.1 3.1 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.7 EIM89462.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.5 3 0 0 3 3 3 0 F-box-like DUF1106 PF06523.11 EIM89462.1 - 0.19 11.8 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) DUF5127 PF17168.4 EIM89463.1 - 5.8e-69 232.3 0.0 1.3e-68 231.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EIM89463.1 - 1.1e-45 155.4 0.6 1.8e-45 154.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EIM89463.1 - 6.7e-17 62.4 0.1 5e-15 56.3 0.4 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EIM89463.1 - 6.1e-06 25.7 0.3 1.8e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) SecY PF00344.20 EIM89464.1 - 0.0027 17.0 0.2 0.003 16.9 0.2 1.0 1 0 0 1 1 1 1 SecY translocase B_solenoid_ydck PF18836.1 EIM89466.1 - 0.04 13.8 0.7 2.5 8.1 0.0 3.2 3 0 0 3 3 3 0 Beta solenoid repeat from YDCK Sld3_N PF18523.1 EIM89466.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Sld3 N-terminal domain ITAM_Cys-rich PF10538.9 EIM89466.1 - 0.3 10.9 3.5 7.3 6.4 0.3 2.5 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif Gly_transf_sug PF04488.15 EIM89467.1 - 3.2e-05 24.5 0.0 6.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EIM89467.1 - 0.0023 17.4 0.5 0.0036 16.7 0.5 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein LexA_DNA_bind PF01726.16 EIM89467.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain Mito_carr PF00153.27 EIM89468.1 - 1.1e-28 98.9 5.3 2.8e-15 56.0 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.7 EIM89469.1 - 1.3e-08 35.7 15.1 4.2e-08 34.1 15.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM89469.1 - 3e-06 27.1 0.1 1.2e-05 25.1 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4632 PF15451.6 EIM89469.1 - 0.061 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Chlorophyllase PF07224.11 EIM89469.1 - 0.23 10.5 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Cation_efflux PF01545.21 EIM89470.1 - 0.59 9.8 10.7 3.1 7.5 0.4 2.4 3 0 0 3 3 3 0 Cation efflux family Glyco_hydro_61 PF03443.14 EIM89471.1 - 1.3e-54 185.3 0.0 1.5e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.28 EIM89472.1 - 7.2e-91 305.6 0.0 9.3e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM89472.1 - 5.1e-05 23.2 2.4 0.0051 16.7 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM89472.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pro-kuma_activ PF09286.11 EIM89476.1 - 5.4e-36 124.0 0.3 1.9e-35 122.3 0.1 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EIM89476.1 - 2.3e-05 23.8 1.2 3.9e-05 23.0 1.2 1.3 1 0 0 1 1 1 1 Subtilase family G-patch_2 PF12656.7 EIM89477.1 - 4.1e-20 71.6 0.4 2.1e-19 69.3 0.4 2.4 1 0 0 1 1 1 1 G-patch domain Haem_degrading PF03928.14 EIM89478.1 - 1.1e-17 64.2 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Haem-degrading adh_short PF00106.25 EIM89480.1 - 9.3e-24 84.0 0.0 1.4e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89480.1 - 8.9e-18 64.7 0.0 1.2e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89480.1 - 0.0057 16.6 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 1 KR domain YjeF_N PF03853.15 EIM89480.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus RRM_1 PF00076.22 EIM89482.1 - 1.8e-26 91.7 0.0 1.8e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM89482.1 - 0.001 19.1 0.0 0.0059 16.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EIM89482.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIM89482.1 - 0.092 12.6 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RNA_bind PF08675.11 EIM89482.1 - 0.098 12.7 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain VIT PF08487.10 EIM89482.1 - 0.16 12.1 0.7 0.31 11.3 0.7 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain YCII PF03795.14 EIM89483.1 - 1.3e-10 41.5 0.1 1.4e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 YCII-related domain Formyl_trans_N PF00551.19 EIM89484.1 - 1.1e-34 119.8 0.0 7.5e-17 61.7 0.1 2.1 2 0 0 2 2 2 2 Formyl transferase RRM_1 PF00076.22 EIM89486.1 - 1.2e-19 69.9 0.1 5.8e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EIM89486.1 - 0.16 11.8 0.0 0.58 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_1 PF00076.22 EIM89487.1 - 2.4e-26 91.3 0.0 2.4e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EIM89487.1 - 0.0068 16.5 0.5 3.8 7.7 0.1 2.6 2 1 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 EIM89487.1 - 0.0095 15.8 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EIM89487.1 - 0.13 12.4 0.0 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 RNA binding motif Haem_degrading PF03928.14 EIM89490.1 - 6.1e-31 106.9 0.1 2.2e-29 101.9 0.1 2.0 1 1 0 1 1 1 1 Haem-degrading SBF_like PF13593.6 EIM89490.1 - 0.011 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) FB_lectin PF07367.11 EIM89492.1 - 8e-54 181.4 0.3 8.9e-54 181.2 0.3 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin YCII PF03795.14 EIM89493.1 - 1.4e-06 28.6 0.0 1.6e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Peptidase_A21 PF03566.13 EIM89493.1 - 0.028 12.7 0.0 0.033 12.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 DUF1923 PF09083.10 EIM89493.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) rve PF00665.26 EIM89496.1 - 0.0069 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 EIM89498.1 - 0.0047 17.5 0.0 0.013 16.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EIM89498.1 - 0.06 13.9 0.0 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Aldo_ket_red PF00248.21 EIM89500.1 - 6.3e-24 84.7 0.0 1.3e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family PPDK_N PF01326.19 EIM89500.1 - 0.087 12.1 0.1 0.37 10.0 0.0 1.9 2 1 1 3 3 3 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain EphA2_TM PF14575.6 EIM89501.1 - 0.00022 22.0 0.2 0.21 12.5 0.0 2.4 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EIM89501.1 - 0.015 15.2 10.2 0.07 13.0 0.7 3.0 2 1 1 3 3 3 0 TMEM154 protein family DUF4064 PF13273.6 EIM89501.1 - 0.019 15.2 0.1 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) RIFIN PF02009.16 EIM89501.1 - 0.095 12.6 0.1 8.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Rifin 7TM_GPCR_Sru PF10322.9 EIM89501.1 - 0.12 11.7 0.1 17 4.6 0.0 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF4690 PF15756.5 EIM89501.1 - 0.21 12.2 11.3 0.24 12.0 1.4 3.3 3 0 0 3 3 3 0 Small Novel Rich in Cartilage HLH PF00010.26 EIM89502.1 - 5.4e-12 45.5 1.3 9.3e-12 44.7 1.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 EIM89502.1 - 0.0086 16.1 10.7 0.13 12.3 0.3 3.0 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 PRR20 PF15708.5 EIM89502.1 - 0.029 14.3 2.6 0.062 13.2 2.6 1.5 1 0 0 1 1 1 0 Proline-rich protein family 20 TFIIA PF03153.13 EIM89502.1 - 0.22 11.5 10.5 0.86 9.5 5.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PLA2_B PF01735.18 EIM89503.1 - 2.9e-91 306.4 0.2 5.5e-91 305.4 0.2 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain CxC5 PF18718.1 EIM89505.1 - 3.3e-31 107.8 4.1 5.5e-31 107.1 1.1 2.8 3 0 0 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EIM89505.1 - 4.6e-24 84.5 6.0 4.6e-24 84.5 6.0 2.6 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Coilin_N PF15862.5 EIM89505.1 - 0.24 11.2 0.0 0.41 10.4 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus F-box-like PF12937.7 EIM89507.1 - 4.9e-05 23.1 0.2 0.00011 22.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like Cauli_VI PF01693.16 EIM89509.1 - 1.2e-05 25.5 0.0 0.0004 20.6 0.0 2.5 2 0 0 2 2 2 1 Caulimovirus viroplasmin SIR2 PF02146.17 EIM89512.1 - 1.5e-21 77.1 0.0 4.5e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Sir2 family MCPVI PF02993.14 EIM89513.1 - 0.11 12.3 5.6 0.21 11.4 5.6 1.4 1 0 0 1 1 1 0 Minor capsid protein VI PGA2 PF07543.12 EIM89513.1 - 9.1 6.3 19.5 0.095 12.7 4.5 3.2 3 0 0 3 3 3 0 Protein trafficking PGA2 SMC_N PF02463.19 EIM89514.1 - 0.017 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain 2OG-FeII_Oxy_3 PF13640.6 EIM89515.1 - 0.1 13.5 0.0 0.13 13.2 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TDP43_N PF18694.1 EIM89516.1 - 0.9 9.4 3.3 48 3.9 0.0 3.6 4 0 0 4 4 4 0 Transactive response DNA-binding protein N-terminal domain F-box-like PF12937.7 EIM89517.1 - 0.00017 21.4 1.8 0.00046 20.0 1.8 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM89520.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM89523.1 - 1.5e-06 28.0 0.0 2.4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM89523.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 F-box domain zinc-ribbons_6 PF07191.12 EIM89524.1 - 0.0081 16.1 0.8 0.015 15.3 0.8 1.4 1 0 0 1 1 1 1 zinc-ribbons RINGv PF12906.7 EIM89524.1 - 0.066 13.3 2.0 0.13 12.4 2.0 1.5 1 0 0 1 1 1 0 RING-variant domain Glyco_hydro_1 PF00232.18 EIM89524.1 - 0.071 11.5 0.0 0.076 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 RecR PF02132.15 EIM89524.1 - 0.097 12.3 2.0 0.19 11.3 2.0 1.5 1 0 0 1 1 1 0 RecR protein Herpes_UL47 PF03362.13 EIM89525.1 - 0.066 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL47 protein COesterase PF00135.28 EIM89527.1 - 3.2e-76 257.3 0.0 8.1e-76 255.9 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM89527.1 - 5.6e-09 36.2 0.6 2.5e-08 34.0 0.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM89527.1 - 0.0069 15.9 0.3 0.012 15.1 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Carboxyl_trans PF01039.22 EIM89529.1 - 5.2e-132 441.0 0.2 6.6e-132 440.6 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 EIM89529.1 - 0.029 13.7 0.1 0.07 12.4 0.1 1.6 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase RabGAP-TBC PF00566.18 EIM89532.1 - 3.9e-38 131.3 0.0 8e-38 130.2 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.20 EIM89533.1 - 1.7e-18 66.5 0.4 3.1e-18 65.6 0.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region AAA PF00004.29 EIM89534.1 - 6.8e-16 58.9 0.0 3.3e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM89534.1 - 0.0017 18.7 0.1 0.086 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 EIM89534.1 - 0.019 14.7 0.4 0.034 13.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EIM89534.1 - 0.02 15.2 0.3 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIM89534.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EIM89534.1 - 0.04 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 EIM89534.1 - 0.062 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 EIM89534.1 - 0.068 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EIM89534.1 - 0.075 13.4 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EIM89534.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FAD_binding_7 PF03441.14 EIM89535.1 - 6.4e-66 221.7 0.0 1e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EIM89535.1 - 9.1e-40 136.3 0.4 1.5e-39 135.7 0.4 1.3 1 0 0 1 1 1 1 DNA photolyase p450 PF00067.22 EIM89536.1 - 3.2e-73 247.1 0.0 3.7e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EIM89537.1 - 7.8e-34 117.1 25.9 9.9e-34 116.8 25.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4064 PF13273.6 EIM89537.1 - 0.059 13.7 7.8 0.31 11.3 0.0 4.1 3 2 0 3 3 3 0 Protein of unknown function (DUF4064) Neurensin PF14927.6 EIM89537.1 - 0.94 9.2 3.6 1.9 8.2 0.3 2.9 3 0 0 3 3 3 0 Neurensin RPN7 PF10602.9 EIM89538.1 - 3.2e-56 189.8 0.5 4.8e-56 189.2 0.5 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EIM89538.1 - 3.2e-16 59.7 0.0 1.1e-15 58.1 0.0 1.9 1 1 1 2 2 2 1 PCI domain RPN6_N PF18055.1 EIM89539.1 - 8.3e-46 155.1 0.8 2.3e-45 153.7 0.5 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EIM89539.1 - 1.8e-18 67.0 0.0 5.5e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 EIM89539.1 - 8.3e-10 38.2 1.3 1.9e-09 37.1 0.7 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 EIM89539.1 - 0.00012 21.8 0.6 0.15 12.2 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM89539.1 - 0.0015 18.4 0.0 6.7 7.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM89539.1 - 0.0025 17.3 1.8 0.0033 16.9 0.2 2.0 3 0 0 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 EIM89539.1 - 0.079 12.9 0.1 6.7 6.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89539.1 - 0.087 13.1 6.0 12 6.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DDRGK PF09756.9 EIM89539.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 DDRGK domain TPR_14 PF13428.6 EIM89539.1 - 0.8 10.7 4.2 1.4e+02 3.7 0.8 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat NAD_binding_10 PF13460.6 EIM89540.1 - 8.5e-15 55.1 0.0 5.3e-06 26.5 0.0 2.2 2 1 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 EIM89540.1 - 0.054 13.0 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Arginase PF00491.21 EIM89541.1 - 4.8e-83 278.9 0.0 5.9e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EIM89541.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Glyco_transf_15 PF01793.16 EIM89542.1 - 6.9e-63 212.9 0.5 8.9e-63 212.5 0.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Exo70 PF03081.15 EIM89544.1 - 4.7e-42 144.4 0.0 1.3e-41 142.9 0.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Urb2 PF10441.9 EIM89544.1 - 0.054 13.4 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 Urb2/Npa2 family NPR1_interact PF15699.5 EIM89544.1 - 0.52 11.0 3.3 1 10.0 3.3 1.4 1 0 0 1 1 1 0 NPR1 interacting DnaJ PF00226.31 EIM89545.1 - 1.7e-13 50.5 0.3 1.7e-13 50.5 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain Ank_2 PF12796.7 EIM89545.1 - 2e-13 50.7 0.1 1.1e-11 45.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM89545.1 - 6.1e-13 49.0 0.0 2.4e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM89545.1 - 1.7e-09 37.1 0.0 0.076 13.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EIM89545.1 - 2e-08 34.3 0.0 2.8e-05 24.3 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EIM89545.1 - 3.6e-07 30.3 0.4 0.6 10.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat AIM24 PF01987.17 EIM89546.1 - 9.2e-51 172.5 0.0 1.1e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AP_endonuc_2 PF01261.24 EIM89548.1 - 6.7e-32 110.6 0.0 9.8e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel COesterase PF00135.28 EIM89549.1 - 1.7e-85 287.9 0.3 2.2e-85 287.5 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM89549.1 - 9.3e-08 32.2 0.2 8.9e-07 29.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM89549.1 - 0.0098 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Response_reg PF00072.24 EIM89550.1 - 1.2e-23 83.4 0.2 2.1e-23 82.6 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DUF1631 PF07793.11 EIM89550.1 - 2.3 6.5 6.5 3.4 6.0 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) HSF_DNA-bind PF00447.17 EIM89551.1 - 2.8e-32 111.2 3.8 2.8e-32 111.2 3.8 1.5 2 0 0 2 2 2 1 HSF-type DNA-binding Leu_zip PF15294.6 EIM89551.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Leucine zipper Snapin_Pallidin PF14712.6 EIM89551.1 - 0.012 16.0 0.4 0.012 16.0 0.4 2.1 3 0 0 3 3 3 0 Snapin/Pallidin Use1 PF09753.9 EIM89551.1 - 0.018 14.7 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 ZapB PF06005.12 EIM89551.1 - 0.049 14.1 0.4 0.089 13.3 0.4 1.3 1 0 0 1 1 1 0 Cell division protein ZapB ATG16 PF08614.11 EIM89551.1 - 1.2 9.3 4.6 3.7 7.7 4.6 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Sybindin PF04099.12 EIM89552.1 - 7.1e-40 136.2 0.0 8.6e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EIM89552.1 - 1.1e-06 28.8 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region COesterase PF00135.28 EIM89554.1 - 2.7e-69 234.4 0.2 3.4e-69 234.1 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM89554.1 - 6.8e-09 35.9 0.6 2.3e-08 34.2 0.6 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM89554.1 - 0.044 12.6 0.0 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase COesterase PF00135.28 EIM89555.1 - 2.1e-81 274.3 0.1 2.8e-81 273.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM89555.1 - 4.6e-09 36.4 1.3 6.1e-08 32.8 1.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EIM89555.1 - 0.024 14.3 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 EIM89555.1 - 0.026 14.0 0.1 0.055 12.9 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 EIM89556.1 - 1.1e-84 285.2 0.1 1.5e-84 284.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM89556.1 - 4.1e-07 30.1 1.1 3.9e-06 26.9 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM89556.1 - 0.028 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 EIM89556.1 - 0.034 13.8 0.1 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 EIM89556.1 - 0.13 11.1 0.0 0.73 8.6 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase NAD_binding_10 PF13460.6 EIM89557.1 - 1.4e-11 44.7 0.0 1.6e-06 28.1 0.0 2.5 2 1 0 2 2 2 2 NAD(P)H-binding ApbA PF02558.16 EIM89557.1 - 0.095 12.3 0.1 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Qn_am_d_aII PF14930.6 EIM89557.1 - 0.099 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II LSM14 PF12701.7 EIM89560.1 - 1.1e-24 86.4 0.0 1.7e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EIM89560.1 - 6.1e-06 27.1 12.1 6.1e-06 27.1 12.1 2.5 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 EIM89560.1 - 0.00013 22.1 0.0 0.00035 20.7 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain Pex14_N PF04695.13 EIM89560.1 - 0.027 15.2 15.9 0.027 15.2 15.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 EIM89560.1 - 0.58 9.8 4.8 1.1 8.9 4.8 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EIM89560.1 - 0.68 9.2 4.6 1 8.6 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EIM89560.1 - 6.2 5.0 5.7 8.1 4.6 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Clathrin PF00637.20 EIM89561.1 - 3.5e-14 52.9 0.1 1.6e-09 37.8 0.3 3.1 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 EIM89561.1 - 1.8e-12 47.3 0.2 3.5e-12 46.4 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EIM89561.1 - 1.3e-09 37.9 9.1 2.8e-09 36.8 9.1 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EIM89561.1 - 0.01 15.7 8.9 0.018 14.9 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM89561.1 - 0.034 14.5 8.4 0.07 13.5 8.4 1.5 1 0 0 1 1 1 0 Ring finger domain TPR_11 PF13414.6 EIM89561.1 - 0.097 12.4 0.2 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 TPR repeat zf-RING_5 PF14634.6 EIM89561.1 - 1 9.4 8.7 1.9 8.5 8.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 EIM89561.1 - 4.7 7.6 8.2 9.1 6.7 8.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain ATP-synt_J PF04911.12 EIM89562.1 - 1e-24 85.8 1.0 1.3e-24 85.5 1.0 1.2 1 0 0 1 1 1 1 ATP synthase j chain Adenylsucc_synt PF00709.21 EIM89564.1 - 1.6e-173 577.5 0.0 1.8e-173 577.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase COX16 PF14138.6 EIM89565.1 - 1e-31 109.3 0.1 1.2e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 zf-MYND PF01753.18 EIM89566.1 - 1.1e-09 38.2 10.4 2.7e-09 37.0 10.4 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EIM89566.1 - 9e-05 22.5 5.6 0.0024 17.9 4.4 2.6 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 AZUL PF16558.5 EIM89566.1 - 0.00015 22.0 0.9 0.00036 20.7 0.1 2.0 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A E1_dh PF00676.20 EIM89567.1 - 6.3e-116 386.5 0.0 7.5e-116 386.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EIM89567.1 - 0.00013 21.3 0.1 0.0006 19.1 0.1 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Arm PF00514.23 EIM89568.1 - 1.2e-17 63.3 18.4 8.5e-06 25.6 0.0 9.3 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EIM89568.1 - 3e-12 45.7 26.2 0.062 13.6 0.0 11.0 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.6 EIM89568.1 - 1.5e-10 41.3 15.5 2.3e-07 31.1 0.0 7.2 6 3 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 EIM89568.1 - 1.5e-05 25.3 28.3 0.019 15.5 0.3 8.4 8 3 1 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.20 EIM89568.1 - 7.9e-05 21.4 1.1 0.0031 16.1 0.0 3.5 3 1 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 EIM89568.1 - 0.001 19.1 0.1 0.085 12.9 0.0 3.8 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EIM89568.1 - 0.09 12.9 0.1 17 5.6 0.0 3.4 4 0 0 4 4 4 0 V-ATPase subunit H RdRP PF05183.12 EIM89569.1 - 2.9e-144 481.9 0.0 3.8e-144 481.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase COG6 PF06419.11 EIM89570.1 - 2.4e-144 481.9 0.0 3.4e-144 481.5 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 EIM89570.1 - 0.08 13.0 0.2 0.22 11.6 0.2 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EIM89570.1 - 0.3 11.1 1.3 2.8 8.0 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Flagellin_C PF00700.21 EIM89570.1 - 0.34 11.3 1.5 6.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Tugs PF17840.1 EIM89570.1 - 0.43 10.8 2.2 1.7 8.9 0.4 2.8 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain ATG16 PF08614.11 EIM89570.1 - 1.7 8.8 5.2 0.86 9.8 0.5 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Coa1 PF08695.10 EIM89571.1 - 8.6e-32 109.3 0.1 1.1e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF3669 PF12417.8 EIM89571.1 - 0.13 12.5 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger protein PRIMA1 PF16101.5 EIM89571.1 - 0.44 10.6 2.1 0.82 9.7 2.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LepB_GAP_N PF18172.1 EIM89573.1 - 0.74 9.7 0.0 0.74 9.7 0.0 2.6 3 1 0 3 3 3 0 LepB GAP domain N-terminal subdomain Peptidase_M28 PF04389.17 EIM89577.1 - 1.2e-36 126.3 0.0 1.9e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 p450 PF00067.22 EIM89578.1 - 4.7e-56 190.5 0.0 3.8e-55 187.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 RdRP PF05183.12 EIM89579.1 - 9.8e-172 572.6 0.0 1.5e-171 572.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase TPR_10 PF13374.6 EIM89580.1 - 2.1e-61 202.3 37.3 7.3e-08 32.0 0.1 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89580.1 - 3.7e-60 200.1 68.1 2.5e-11 43.7 0.1 8.3 1 1 7 9 9 9 9 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 EIM89580.1 - 4.7e-60 203.1 0.0 9.4e-60 202.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM89580.1 - 7.2e-45 153.4 0.0 1.3e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPR_7 PF13176.6 EIM89580.1 - 3e-08 33.1 17.6 0.024 14.6 0.3 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM89580.1 - 5e-06 26.3 11.1 1 9.7 0.0 6.5 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM89580.1 - 0.00023 21.0 35.7 0.057 13.6 0.2 9.3 10 0 0 10 10 8 1 Tetratricopeptide repeat PPR PF01535.20 EIM89580.1 - 0.00029 20.9 0.1 9.7 6.7 0.0 5.9 5 0 0 5 5 5 1 PPR repeat ANAPC3 PF12895.7 EIM89580.1 - 0.00036 20.7 11.1 0.11 12.8 0.0 5.0 3 3 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 EIM89580.1 - 0.0022 17.5 10.2 12 5.2 0.2 5.4 3 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP RIO1 PF01163.22 EIM89580.1 - 0.0038 16.8 0.1 0.0097 15.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family TPR_1 PF00515.28 EIM89580.1 - 0.0043 16.8 18.0 0.049 13.5 0.0 7.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89580.1 - 0.0092 16.7 31.0 3.2 8.8 1.0 8.7 8 1 1 9 9 7 1 Tetratricopeptide repeat Kdo PF06293.14 EIM89580.1 - 0.014 14.8 2.1 0.048 13.0 0.2 2.7 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4726 PF15855.5 EIM89580.1 - 0.04 14.1 0.2 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) DUF2225 PF09986.9 EIM89580.1 - 0.051 13.3 2.0 0.7 9.6 0.2 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.6 EIM89580.1 - 0.21 12.2 38.8 0.51 11.0 1.0 8.3 6 2 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM89580.1 - 7.6 7.4 17.7 9.1 7.2 0.2 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat Ecl1 PF12855.7 EIM89581.1 - 5e-07 31.0 26.3 5e-07 31.0 26.3 2.6 1 1 0 2 2 2 1 ECL1/2/3 zinc binding proteins Metallothio_Pro PF02069.16 EIM89581.1 - 0.04 14.2 2.1 0.078 13.2 2.1 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-MYND PF01753.18 EIM89581.1 - 0.26 11.4 3.0 0.58 10.3 3.0 1.6 1 0 0 1 1 1 0 MYND finger DUF2116 PF09889.9 EIM89581.1 - 0.86 9.6 4.1 2 8.5 4.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Vps54 PF07928.12 EIM89583.1 - 3.7e-53 179.5 0.6 9.5e-53 178.2 0.6 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 EIM89583.1 - 1.4e-05 25.0 0.1 2.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) GST_C_6 PF17171.4 EIM89584.1 - 3.8e-14 52.2 0.0 7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM89584.1 - 0.00021 21.3 0.0 0.00053 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM89584.1 - 0.018 15.7 0.0 0.066 14.0 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain WD40 PF00400.32 EIM89586.1 - 3.5e-100 325.1 25.9 7.5e-11 42.4 0.2 11.0 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89586.1 - 9.2e-36 122.0 1.4 0.013 15.8 0.0 9.6 1 1 8 9 9 9 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM89586.1 - 1.8e-24 86.4 5.2 0.081 11.9 0.0 9.8 1 1 9 10 10 10 8 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM89586.1 - 5.2e-20 72.0 0.0 0.0047 16.3 0.0 5.7 4 1 1 5 5 5 5 WD40-like domain eIF2A PF08662.11 EIM89586.1 - 7e-15 55.4 0.0 0.0015 18.4 0.0 4.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 EIM89586.1 - 4.4e-13 49.5 0.0 9.2e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 EIM89586.1 - 4.5e-13 48.8 8.7 10 6.2 0.0 9.3 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EIM89586.1 - 1.8e-11 43.4 0.4 5.1 5.6 0.0 8.8 2 2 7 9 9 9 1 Nucleoporin Nup120/160 AAA_16 PF13191.6 EIM89586.1 - 1e-08 35.8 0.3 3.1e-08 34.2 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF285 PF03382.14 EIM89586.1 - 5.9e-07 29.3 0.1 0.72 9.6 0.0 4.7 2 1 2 5 5 5 2 Mycoplasma protein of unknown function, DUF285 Frtz PF11768.8 EIM89586.1 - 6.1e-07 28.1 0.0 4.6 5.4 0.0 6.4 2 1 3 7 7 7 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EIM89586.1 - 3.9e-06 26.4 9.6 1.1 8.5 0.2 7.9 1 1 7 8 8 8 1 Neuroblastoma-amplified sequence, N terminal MlaA PF04333.13 EIM89586.1 - 0.00031 20.5 0.0 6.8 6.3 0.0 5.7 2 1 4 7 7 7 1 MlaA lipoprotein PQQ PF01011.21 EIM89586.1 - 0.00061 19.6 0.0 1.5e+02 2.6 0.0 6.8 8 0 0 8 8 8 0 PQQ enzyme repeat DUF374 PF04028.13 EIM89586.1 - 0.011 15.3 0.3 86 2.8 0.0 5.5 3 1 3 6 6 6 0 Domain of unknown function (DUF374) Peptidase_S9_N PF02897.15 EIM89586.1 - 0.02 13.7 4.2 12 4.6 0.0 5.2 2 2 5 7 7 7 0 Prolyl oligopeptidase, N-terminal beta-propeller domain APS_kinase PF01583.20 EIM89586.1 - 0.047 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 EIM89586.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EIM89586.1 - 0.099 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 EIM89586.1 - 0.12 12.7 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EIM89586.1 - 0.14 12.2 0.0 0.7 10.0 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MauJ PF17419.2 EIM89586.1 - 0.15 11.5 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ DUF5570 PF17731.1 EIM89586.1 - 0.17 12.0 14.3 13 5.9 0.1 6.5 2 1 4 8 8 8 0 Family of unknown function (DUF5570) DUF16 PF01519.16 EIM89586.1 - 0.28 11.7 2.5 19 5.8 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4279 PF14106.6 EIM89586.1 - 0.44 10.8 7.5 27 5.0 0.0 6.5 5 3 3 8 8 8 0 Domain of unknown function (DUF4279) TPR_10 PF13374.6 EIM89587.1 - 8.3e-50 165.4 15.7 4e-07 29.7 0.0 9.8 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89587.1 - 4e-44 148.8 11.6 7e-14 51.9 0.0 5.5 3 1 2 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 EIM89587.1 - 2e-14 52.5 1.0 0.28 11.4 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIM89587.1 - 9.4e-13 47.2 6.6 0.055 13.5 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM89587.1 - 3.5e-10 40.3 11.4 0.0023 18.5 0.0 5.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89587.1 - 4.6e-10 39.4 8.7 7 7.7 0.1 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM89587.1 - 7.6e-09 35.1 0.1 0.1 12.9 0.0 6.2 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIM89587.1 - 8.5e-09 35.5 5.6 9.4 7.1 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM89587.1 - 1.1e-08 34.5 0.0 0.46 10.4 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM89587.1 - 2.1e-06 27.9 0.1 0.5 10.6 0.1 4.9 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EIM89587.1 - 6.6e-05 23.3 0.2 31 5.2 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIM89587.1 - 0.00053 20.4 13.8 1.4 9.8 0.3 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat PPR PF01535.20 EIM89587.1 - 0.0033 17.6 0.1 20 5.7 0.0 5.6 7 0 0 7 7 7 0 PPR repeat Paf67 PF10255.9 EIM89587.1 - 0.18 10.8 0.0 9.7 5.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TRAM_LAG1_CLN8 PF03798.16 EIM89588.1 - 2.7e-30 105.6 14.6 4e-30 105.1 14.6 1.2 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.25 EIM89590.1 - 9.2e-47 159.6 0.0 1.1e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89590.1 - 2.3e-30 105.8 0.0 2.9e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM89590.1 - 1.1e-05 24.9 0.0 0.0033 16.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.11 EIM89590.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EIM89590.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family COX7C PF02935.16 EIM89591.1 - 2.9e-05 24.2 0.2 5.3e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc COX7C PF02935.16 EIM89592.1 - 1.9e-08 34.4 0.2 2.3e-08 34.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc G-gamma PF00631.22 EIM89593.1 - 2.1e-23 82.1 0.0 2.4e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain COG5 PF10392.9 EIM89593.1 - 0.051 13.8 0.2 0.056 13.6 0.2 1.0 1 0 0 1 1 1 0 Golgi transport complex subunit 5 G-gamma PF00631.22 EIM89594.1 - 3.5e-24 84.6 0.0 3.9e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain Thioredoxin PF00085.20 EIM89595.1 - 2.1e-22 79.1 0.0 2.6e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIM89595.1 - 9.8e-09 35.6 0.2 1.9e-07 31.5 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIM89595.1 - 3.9e-06 27.1 0.0 1.6e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EIM89595.1 - 0.0015 17.9 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EIM89595.1 - 0.0017 18.5 0.1 0.0025 18.0 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EIM89595.1 - 0.0021 18.0 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIM89595.1 - 0.0051 16.5 0.1 0.016 14.9 0.1 1.8 1 1 1 2 2 2 1 Redoxin TraF PF13728.6 EIM89595.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 F plasmid transfer operon protein Cu_bind_like PF02298.17 EIM89596.1 - 0.00021 21.2 0.4 0.001 19.0 0.4 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 EIM89596.1 - 0.013 15.9 0.5 0.034 14.6 0.2 1.7 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Bul1_C PF04426.12 EIM89598.1 - 0.073 12.5 0.3 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 Bul1 C terminus Mem_trans PF03547.18 EIM89600.1 - 1.7e-22 79.4 6.4 2.9e-22 78.6 6.4 1.3 1 1 0 1 1 1 1 Membrane transport protein DUF3951 PF13131.6 EIM89600.1 - 3.2 8.0 6.7 2.5 8.3 2.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Pkinase_Tyr PF07714.17 EIM89601.1 - 1.5e-40 139.1 0.0 1.7e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM89601.1 - 1.1e-30 106.9 0.0 1.4e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIM89601.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EIM89601.1 - 0.08 12.9 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM89601.1 - 0.18 10.6 0.1 0.23 10.2 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EIM89601.1 - 0.2 10.6 0.2 0.3 10.0 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TPR_10 PF13374.6 EIM89602.1 - 1.3e-66 218.8 27.4 4.5e-07 29.5 0.0 12.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89602.1 - 9.3e-66 218.1 26.0 6.4e-13 48.8 0.3 8.5 6 1 3 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 EIM89602.1 - 7.2e-21 72.6 10.4 0.062 13.4 0.0 10.4 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 EIM89602.1 - 2.7e-19 69.4 12.2 0.00058 20.3 0.0 8.2 6 2 2 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM89602.1 - 5.5e-15 55.4 4.0 0.071 13.3 0.0 8.3 3 1 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EIM89602.1 - 8.6e-14 50.5 14.7 0.86 9.9 0.0 10.5 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM89602.1 - 6.5e-12 44.7 0.5 8.8 6.3 0.0 9.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM89602.1 - 3.8e-11 42.3 1.2 1.8 8.9 0.0 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM89602.1 - 6.2e-11 42.2 4.5 2.7 8.8 0.0 9.2 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89602.1 - 6e-10 39.1 28.7 1.8 9.6 0.0 10.8 10 2 2 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM89602.1 - 3.9e-07 30.6 32.1 0.0024 18.5 0.0 8.8 7 3 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIM89602.1 - 0.00026 21.1 3.2 1.3e+02 3.3 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIM89602.1 - 0.0015 18.9 39.7 1.3 9.9 0.1 11.1 12 1 0 12 12 12 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM89602.1 - 0.0051 16.9 0.3 38 4.4 0.0 4.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EIM89602.1 - 0.0073 16.3 9.8 14 5.8 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 EIM89602.1 - 0.16 12.3 0.0 22 5.6 0.0 4.2 4 0 0 4 4 4 0 PPR repeat Myotub-related PF06602.14 EIM89604.1 - 9.6e-147 488.5 0.0 1.4e-146 488.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 EIM89604.1 - 0.00053 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 EIM89604.1 - 0.021 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain HTH_29 PF13551.6 EIM89604.1 - 0.034 14.2 0.0 0.094 12.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Y_phosphatase3 PF13350.6 EIM89604.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family S-AdoMet_synt_C PF02773.16 EIM89606.1 - 1.6e-68 229.0 0.9 4e-68 227.7 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EIM89606.1 - 2.1e-47 160.3 0.0 3.6e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EIM89606.1 - 1.5e-44 150.7 0.9 2.2e-44 150.2 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EIM89606.1 - 0.024 13.4 0.1 0.16 10.7 0.1 2.0 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) GATase_6 PF13522.6 EIM89607.1 - 1.1e-12 48.2 0.0 2.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EIM89607.1 - 4.5e-10 39.5 0.0 7.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EIM89607.1 - 9.2e-09 35.0 0.1 1.5e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EIM89607.1 - 3.9e-05 22.7 0.0 0.00011 21.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II S-methyl_trans PF02574.16 EIM89607.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase DUF5077 PF16871.5 EIM89608.1 - 7.9e-57 192.3 0.7 1.4e-56 191.5 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF3472 PF11958.8 EIM89608.1 - 3.7e-53 180.5 4.7 7.8e-53 179.5 4.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Glyoxal_oxid_N PF07250.11 EIM89609.1 - 3.5e-35 121.3 0.0 2.8e-34 118.4 0.0 2.3 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIM89609.1 - 1.4e-22 79.7 0.1 3.5e-21 75.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) CE2_N PF17996.1 EIM89609.1 - 0.057 13.4 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Kelch_4 PF13418.6 EIM89609.1 - 0.064 13.3 0.0 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain CBM_2 PF00553.19 EIM89609.1 - 0.066 13.5 0.0 6.9 7.0 0.0 3.2 2 0 0 2 2 2 0 Cellulose binding domain TPR_10 PF13374.6 EIM89610.1 - 1.3e-100 326.9 52.9 1.3e-08 34.4 0.0 18.8 17 2 1 18 18 18 17 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89610.1 - 7.1e-93 305.0 51.1 3e-13 49.8 0.0 13.2 5 2 9 14 14 14 14 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 EIM89610.1 - 3.8e-51 173.9 0.0 6.1e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM89610.1 - 2.4e-40 138.6 0.0 7.2e-40 137.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain TPR_8 PF13181.6 EIM89610.1 - 4.3e-24 82.7 6.8 0.0067 16.6 0.0 13.3 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM89610.1 - 2.1e-20 71.1 18.9 0.028 14.5 0.2 14.2 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_7 PF13176.6 EIM89610.1 - 2.8e-20 70.8 17.1 0.005 16.8 0.1 11.9 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 EIM89610.1 - 2.6e-19 69.5 17.6 0.00057 20.3 0.2 10.0 6 2 5 11 11 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 EIM89610.1 - 2.2e-18 65.2 13.5 0.02 14.7 0.1 11.8 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89610.1 - 3.3e-17 61.7 29.8 0.9 10.5 0.1 13.9 13 1 2 15 15 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM89610.1 - 1.5e-14 54.0 31.0 0.012 15.8 3.3 10.8 3 2 5 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EIM89610.1 - 7.9e-12 45.0 11.8 1.5 9.6 0.0 12.6 15 0 0 15 15 13 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM89610.1 - 1.3e-11 45.0 35.4 9.8e-07 29.3 0.4 11.4 11 4 1 12 12 11 2 Tetratricopeptide repeat TPR_4 PF07721.14 EIM89610.1 - 3.5e-09 36.4 5.8 4.2 8.3 0.1 9.7 11 0 0 11 11 9 1 Tetratricopeptide repeat PPR PF01535.20 EIM89610.1 - 0.00025 21.1 2.7 2.5e+02 2.3 0.0 8.3 11 0 0 11 11 8 0 PPR repeat Fis1_TPR_C PF14853.6 EIM89610.1 - 0.016 15.3 12.5 4 7.6 0.1 6.7 8 0 0 8 8 6 0 Fis1 C-terminal tetratricopeptide repeat Paf67 PF10255.9 EIM89610.1 - 0.025 13.6 1.9 15 4.4 0.0 4.4 4 1 1 5 5 5 0 RNA polymerase I-associated factor PAF67 RIO1 PF01163.22 EIM89610.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 RIO1 family TPR_3 PF07720.12 EIM89610.1 - 0.12 12.4 9.9 77 3.4 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 EIM89610.1 - 0.19 11.8 2.6 9.1 6.4 0.1 4.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain WbqC PF08889.11 EIM89610.1 - 0.25 11.3 0.6 46 3.8 0.0 3.7 2 1 2 4 4 4 0 WbqC-like protein family TPR_20 PF14561.6 EIM89610.1 - 0.38 11.1 23.7 2.2 8.7 0.3 9.1 4 2 7 11 11 10 0 Tetratricopeptide repeat Clathrin PF00637.20 EIM89610.1 - 1.7 8.5 5.7 73 3.2 0.1 4.7 5 1 0 5 5 4 0 Region in Clathrin and VPS zf-MYND PF01753.18 EIM89611.1 - 7.8e-08 32.3 12.9 7.8e-08 32.3 12.9 1.6 2 0 0 2 2 2 1 MYND finger tRNA_int_end_N2 PF12928.7 EIM89611.1 - 0.018 15.2 0.3 1.5 9.1 0.1 2.6 3 0 0 3 3 3 0 tRNA-splicing endonuclease subunit sen54 N-term zf-C6H2 PF15801.5 EIM89611.1 - 0.74 10.2 12.2 0.19 12.1 8.3 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 EIM89612.1 - 2.5e-06 27.3 4.4 1.1e-05 25.3 3.2 2.6 2 0 0 2 2 2 1 F-box-like KH_8 PF17903.1 EIM89613.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Krr1 KH1 domain KH_1 PF00013.29 EIM89613.1 - 0.037 13.9 0.9 0.037 13.9 0.9 1.8 2 0 0 2 2 2 0 KH domain DUF3835 PF12927.7 EIM89614.1 - 4e-05 24.4 2.4 0.0012 19.7 0.3 6.9 7 1 0 7 7 7 2 Domain of unknown function (DUF3835) FapA PF03961.13 EIM89614.1 - 0.25 9.9 4.0 0.37 9.3 4.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vfa1 PF08432.10 EIM89614.1 - 4.4 7.6 13.6 8.1 6.7 11.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 F-box-like PF12937.7 EIM89615.1 - 8.5e-06 25.6 2.3 8.5e-06 25.6 2.3 2.1 2 0 0 2 2 2 1 F-box-like DUF3808 PF10300.9 EIM89617.1 - 6.7e-76 255.9 0.0 1.4e-75 254.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EIM89617.1 - 2.2e-05 24.9 1.9 4.9e-05 23.8 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89617.1 - 0.00087 19.9 4.6 13 6.9 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM89617.1 - 0.00093 19.4 0.1 0.0024 18.0 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EIM89617.1 - 0.022 15.4 3.8 0.41 11.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM89617.1 - 0.042 14.0 3.6 4.7 7.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89617.1 - 0.083 13.2 4.5 9.9 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SPX PF03105.19 EIM89617.1 - 6.2 6.6 7.0 5 6.9 1.2 2.3 2 0 0 2 2 2 0 SPX domain DUF1713 PF08213.11 EIM89618.1 - 3.7e-10 39.5 24.4 5.6e-10 39.0 24.4 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) AAA_16 PF13191.6 EIM89619.1 - 0.012 16.0 0.0 0.049 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EIM89619.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GvpD PF07088.11 EIM89619.1 - 0.025 13.2 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein FtsK_SpoIIIE PF01580.18 EIM89619.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 EIM89619.1 - 0.047 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EIM89619.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EIM89619.1 - 0.056 13.3 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 EIM89619.1 - 0.059 13.9 0.0 0.099 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EIM89619.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM89619.1 - 0.063 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EIM89619.1 - 0.068 13.7 0.5 0.15 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 EIM89619.1 - 0.088 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 EIM89619.1 - 0.1 12.3 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EIM89619.1 - 0.11 12.6 0.1 0.88 9.6 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase_2 PF01637.18 EIM89619.1 - 0.11 12.4 0.3 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EIM89619.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIM89619.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EIM89619.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 EIM89619.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI COX4 PF02936.14 EIM89620.1 - 6.8e-33 113.6 0.0 8.7e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1726 PF08351.11 EIM89621.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF382 PF04037.13 EIM89622.1 - 6.2e-59 197.7 1.1 6.2e-59 197.7 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EIM89622.1 - 2.1e-17 62.7 4.6 4.1e-17 61.8 4.6 1.5 1 0 0 1 1 1 1 PSP MitMem_reg PF13012.6 EIM89623.1 - 1.9e-34 118.5 0.6 2.8e-34 117.9 0.6 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EIM89623.1 - 4.5e-30 104.1 0.0 1.1e-29 102.8 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 EIM89623.1 - 0.11 12.2 0.9 0.18 11.5 0.9 1.2 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 EIM89623.1 - 0.39 10.8 2.1 0.65 10.1 2.1 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Arrestin_C PF02752.22 EIM89624.1 - 1.1e-08 35.6 0.1 3.5e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain F-box-like PF12937.7 EIM89625.1 - 8.5e-06 25.6 0.0 2.6e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM89625.1 - 0.0026 17.6 0.2 0.011 15.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain Protoglobin PF11563.8 EIM89626.1 - 2.5e-37 128.2 0.7 2.9e-37 128.0 0.7 1.0 1 0 0 1 1 1 1 Protoglobin PMT PF02366.18 EIM89627.1 - 1.2e-78 264.1 18.4 2.7e-78 262.9 18.4 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EIM89627.1 - 6.1e-59 199.0 11.1 6.1e-59 199.0 11.1 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EIM89627.1 - 4.1e-27 95.2 0.1 6.4e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 MIR domain Fibrillarin PF01269.17 EIM89628.1 - 5.5e-105 349.5 0.0 6.7e-105 349.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EIM89628.1 - 0.00047 19.9 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EIM89628.1 - 0.0016 18.2 0.1 0.0025 17.6 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EIM89628.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EIM89628.1 - 0.028 15.1 0.0 0.044 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EIM89628.1 - 0.078 12.6 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EIM89628.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 EIM89629.1 - 1.8e-17 63.5 0.8 3.2e-17 62.7 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM89629.1 - 4.9e-07 30.9 0.1 0.0043 18.1 0.0 2.7 1 1 2 3 3 3 2 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM89629.1 - 3.1e-05 23.8 0.0 0.00019 21.2 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EIM89629.1 - 0.19 11.2 3.7 0.27 10.7 2.2 1.9 1 1 1 2 2 2 0 short chain dehydrogenase Glyco_transf_22 PF03901.17 EIM89630.1 - 2.7e-82 277.2 9.1 6.9e-82 275.9 9.1 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 EIM89631.1 - 7.3e-56 189.4 0.0 9.6e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89631.1 - 5.7e-33 114.3 0.0 8.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM89631.1 - 2.5e-05 23.8 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM89631.1 - 0.00079 18.8 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EIM89631.1 - 0.0031 16.5 0.0 0.0044 16.0 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 EIM89631.1 - 0.099 12.3 0.1 0.29 10.7 0.0 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AF-4 PF05110.13 EIM89631.1 - 4 5.4 8.4 5.4 5.0 8.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase PF00069.25 EIM89632.1 - 5.5e-35 121.0 0.0 7.3e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89632.1 - 2.5e-15 56.5 0.0 4.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM89632.1 - 4.4e-05 22.9 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIM89632.1 - 0.00062 18.8 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIM89632.1 - 0.0042 17.0 0.4 0.0076 16.2 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM89632.1 - 0.032 13.6 0.2 0.053 12.9 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EIM89632.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.16 EIM89633.1 - 1.4e-31 109.7 27.7 2e-31 109.2 27.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3054 PF11255.8 EIM89633.1 - 0.69 10.4 6.1 0.36 11.4 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) WD40 PF00400.32 EIM89634.1 - 9.9e-42 140.1 20.0 2.7e-07 31.2 0.5 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89634.1 - 2e-19 69.7 0.1 6.6e-05 23.1 0.1 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM89634.1 - 1.3e-07 30.9 1.4 0.05 12.6 0.1 3.8 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EIM89634.1 - 3.7e-07 30.2 0.2 0.00069 19.5 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EIM89634.1 - 0.0032 16.6 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Frtz PF11768.8 EIM89634.1 - 0.012 13.9 0.0 0.23 9.7 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EIM89634.1 - 0.052 12.9 0.2 11 5.3 0.0 3.1 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 EIM89634.1 - 0.072 11.1 0.0 0.12 10.4 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Glyco_transf_18 PF15024.6 EIM89635.1 - 1.2e-09 37.4 0.0 2.6e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 18 HSF_DNA-bind PF00447.17 EIM89636.1 - 9.1e-32 109.5 0.4 1.5e-31 108.9 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EIM89636.1 - 0.0014 19.0 0.1 0.0035 17.8 0.1 1.7 1 0 0 1 1 1 1 Ets-domain CoaE PF01121.20 EIM89637.1 - 1.2e-61 207.5 0.0 1.5e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EIM89637.1 - 0.00014 22.4 0.1 0.001 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EIM89637.1 - 0.18 11.5 0.2 4.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DSPc PF00782.20 EIM89638.1 - 3.4e-22 78.7 0.0 3.5e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain zf-C3HC4_3 PF13920.6 EIM89639.1 - 6e-06 26.0 7.4 6e-06 26.0 7.4 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FOXP-CC PF16159.5 EIM89639.1 - 2 9.1 6.9 1.1 9.9 0.4 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-RING_2 PF13639.6 EIM89639.1 - 2 8.8 23.4 2 8.8 9.3 3.5 3 0 0 3 3 3 0 Ring finger domain FAA_hydrolase PF01557.18 EIM89640.1 - 1.6e-58 197.9 0.0 2.1e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Snapin_Pallidin PF14712.6 EIM89641.1 - 0.00027 21.3 2.7 0.048 14.1 2.6 2.5 1 1 1 2 2 2 2 Snapin/Pallidin Aminotran_1_2 PF00155.21 EIM89641.1 - 0.001 18.4 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II FlaC_arch PF05377.11 EIM89641.1 - 0.0047 17.3 2.3 0.38 11.2 0.1 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 EIM89641.1 - 0.0074 16.3 1.6 0.2 11.6 0.4 2.4 2 1 0 2 2 2 1 Laminin Domain II Tektin PF03148.14 EIM89641.1 - 0.015 14.1 1.6 0.26 10.0 0.2 2.1 2 0 0 2 2 2 0 Tektin family TRAF_BIRC3_bd PF16673.5 EIM89641.1 - 0.018 14.8 0.7 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF1664 PF07889.12 EIM89641.1 - 0.026 14.5 0.8 10 6.2 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tmemb_cc2 PF10267.9 EIM89641.1 - 0.032 13.4 2.3 0.081 12.1 2.3 1.5 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein BDV_P24 PF06595.11 EIM89641.1 - 0.035 14.0 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein XhlA PF10779.9 EIM89641.1 - 0.036 14.3 2.9 0.48 10.7 0.7 2.2 2 0 0 2 2 2 0 Haemolysin XhlA NleF_casp_inhib PF16809.5 EIM89641.1 - 0.044 13.7 0.8 0.17 11.8 0.2 2.0 1 1 1 2 2 2 0 NleF caspase inhibitor Prefoldin_2 PF01920.20 EIM89641.1 - 0.051 13.5 1.0 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit CCDC53 PF10152.9 EIM89641.1 - 0.059 13.8 2.4 0.12 12.8 2.4 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3450 PF11932.8 EIM89641.1 - 0.091 12.1 6.1 0.27 10.5 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EMP24_GP25L PF01105.24 EIM89641.1 - 0.1 12.5 0.7 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.12 EIM89641.1 - 0.11 13.0 0.1 18 5.9 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.6 EIM89641.1 - 0.12 12.8 6.3 5.1 7.6 0.4 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Baculo_PEP_C PF04513.12 EIM89641.1 - 0.12 12.4 1.0 0.45 10.5 0.2 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMCO5 PF14992.6 EIM89641.1 - 0.13 11.8 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 TMCO5 family ADIP PF11559.8 EIM89641.1 - 0.15 12.1 3.6 6.8 6.8 0.1 2.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EIM89641.1 - 0.16 12.1 3.6 0.29 11.3 3.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GP41 PF00517.17 EIM89641.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 2 0 0 2 2 2 0 Retroviral envelope protein DUF4407 PF14362.6 EIM89641.1 - 0.2 10.9 1.5 0.33 10.3 1.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AIP3 PF03915.13 EIM89641.1 - 0.22 10.6 1.1 0.27 10.3 1.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 COG2 PF06148.11 EIM89641.1 - 0.42 10.7 3.2 1.7 8.7 0.9 2.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.12 EIM89641.1 - 0.69 10.2 4.6 26 5.2 0.1 3.3 1 1 1 3 3 3 0 Proteins of 100 residues with WXG Glyco_hydro_79C PF16862.5 EIM89642.1 - 3.4e-07 31.1 0.1 1.4e-06 29.1 0.1 2.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain NARP1 PF12569.8 EIM89644.1 - 0.6 8.9 8.5 0.65 8.8 8.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ANAPC_CDC26 PF10471.9 EIM89644.1 - 2.7 8.9 8.9 1.1 10.1 5.2 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 PAP_assoc PF03828.19 EIM89645.1 - 5.9e-17 61.6 0.0 1.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EIM89645.1 - 3.6e-09 36.8 0.0 7.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3446 PF11928.8 EIM89645.1 - 0.16 12.3 4.8 0.26 11.6 3.3 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain CDC45 PF02724.14 EIM89645.1 - 3.4 5.9 5.0 4.6 5.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Opacity PF02462.15 EIM89647.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Opacity family porin protein zf-CCHC PF00098.23 EIM89648.1 - 0.00084 19.3 0.3 0.0012 18.8 0.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EIM89648.1 - 0.0076 16.0 0.8 0.011 15.4 0.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIM89648.1 - 0.045 13.6 1.0 0.066 13.1 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle ATP-synt_Eps PF04627.13 EIM89649.1 - 3.3e-19 68.6 0.6 3.9e-19 68.4 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.22 EIM89650.1 - 5.1e-51 172.5 0.0 6.3e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM89650.1 - 7e-30 103.7 0.0 1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM89650.1 - 7.8e-11 41.7 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM89650.1 - 5.1e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIM89650.1 - 0.0003 20.4 0.0 0.0035 16.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ORC6 PF05460.13 EIM89650.1 - 0.022 14.1 4.5 0.025 13.8 4.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MGC-24 PF05283.11 EIM89650.1 - 0.71 10.3 7.4 1.2 9.6 7.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DEAD PF00270.29 EIM89651.1 - 1.2e-44 152.2 0.6 1.2e-44 152.2 0.6 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM89651.1 - 1.4e-32 112.3 0.4 1.8e-31 108.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM89651.1 - 1.4e-05 25.1 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIM89651.1 - 0.00039 20.8 1.2 0.0075 16.6 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM89651.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EIM89651.1 - 0.013 15.1 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EIM89651.1 - 0.054 13.8 1.1 0.12 12.6 0.2 2.1 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 EIM89651.1 - 0.097 12.6 0.2 0.47 10.4 0.2 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain F-box-like PF12937.7 EIM89652.1 - 8.2e-09 35.2 4.9 5.1e-08 32.7 2.6 3.2 2 1 0 2 2 2 1 F-box-like Asp_protease_2 PF13650.6 EIM89653.1 - 4.2e-06 27.3 0.0 1.2e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EIM89653.1 - 0.0011 19.5 0.0 0.0025 18.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1863 PF08937.11 EIM89654.1 - 0.025 14.9 0.3 0.046 14.0 0.3 1.4 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF2540 PF10802.8 EIM89656.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) RL10P_insert PF17777.1 EIM89657.1 - 0.09 12.8 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P UCH PF00443.29 EIM89658.1 - 2.3e-41 142.0 0.0 4e-41 141.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM89658.1 - 6.4e-05 22.7 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HMMR_N PF15905.5 EIM89659.1 - 0.00019 21.0 10.5 0.00019 21.0 10.5 3.1 3 1 1 4 4 4 1 Hyaluronan mediated motility receptor N-terminal Fungal_TACC PF12709.7 EIM89659.1 - 0.15 12.6 7.2 6.9 7.2 0.4 4.7 4 1 0 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Bacillus_HBL PF05791.11 EIM89659.1 - 0.47 10.2 4.6 2.5 7.9 0.1 3.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Gp58 PF07902.11 EIM89659.1 - 0.97 7.7 8.6 0.29 9.4 2.9 2.4 1 1 0 2 2 2 0 gp58-like protein FliD_N PF02465.18 EIM89659.1 - 1.9 9.3 13.0 1.8 9.3 1.9 4.2 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 EIM89659.1 - 8.4 6.6 14.8 0.61 10.3 0.8 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Epimerase PF01370.21 EIM89660.1 - 7e-14 51.9 0.0 1.3e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM89660.1 - 3.2e-11 42.8 0.0 5.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM89660.1 - 4.6e-07 29.3 0.0 2.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIM89660.1 - 1.1e-05 25.0 0.4 0.00012 21.6 0.4 2.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EIM89660.1 - 0.0041 16.6 0.1 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EIM89660.1 - 0.0056 16.3 0.1 0.31 10.6 0.1 2.3 2 1 0 2 2 2 1 NmrA-like family Choline_transpo PF04515.12 EIM89661.1 - 3.2e-47 161.3 0.2 3.2e-47 161.3 0.2 2.4 2 2 0 2 2 2 1 Plasma-membrane choline transporter Zip PF02535.22 EIM89661.1 - 0.69 9.1 7.6 1.3 8.2 0.3 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter TFIIA PF03153.13 EIM89661.1 - 2.1 8.2 17.1 4.9 7.0 17.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 EIM89662.1 - 1.9e-127 426.1 0.0 2.4e-127 425.7 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein BUD22 PF09073.10 EIM89662.1 - 0.00067 19.1 0.2 0.00067 19.1 0.2 3.0 3 0 0 3 3 3 1 BUD22 Adap_comp_sub PF00928.21 EIM89663.1 - 7.7e-82 274.6 0.5 9.8e-82 274.3 0.5 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIM89663.1 - 1.2e-05 25.3 0.9 2.2e-05 24.4 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EIM89663.1 - 0.03 13.8 0.2 0.053 13.0 0.2 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF5618 PF18498.1 EIM89663.1 - 0.031 14.5 0.2 0.095 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) 3Beta_HSD PF01073.19 EIM89665.1 - 1.2e-06 27.8 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM89665.1 - 3.7e-06 26.6 0.0 1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EIM89665.1 - 9e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein ATP_bind_3 PF01171.20 EIM89666.1 - 1.7e-36 125.7 0.0 2.7e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 PP-loop family CENP-C_C PF11699.8 EIM89667.1 - 5.3e-26 90.7 0.1 8.4e-26 90.0 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EIM89667.1 - 1.4e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EIM89667.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain CDC27 PF09507.10 EIM89667.1 - 1.7 8.0 32.0 14 4.9 30.9 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PI3K_1B_p101 PF10486.9 EIM89667.1 - 5 4.8 7.3 6.9 4.3 7.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase_fungal PF17667.1 EIM89669.1 - 3.4e-10 39.3 0.5 4e-10 39.0 0.5 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 EIM89670.1 - 5.5e-14 51.8 0.0 6.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM89670.1 - 0.011 15.7 0.1 0.018 15.0 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Terpene_synth_C PF03936.16 EIM89671.1 - 1.2e-05 24.8 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 EIM89671.1 - 4e-05 22.6 0.0 0.0059 15.5 0.0 2.1 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) SPOB_ab PF14682.6 EIM89671.1 - 0.12 12.5 0.1 0.46 10.6 0.0 1.9 2 1 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal DUF3429 PF11911.8 EIM89672.1 - 1.2e-37 129.4 15.1 1.7e-37 128.9 15.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Aha1_N PF09229.11 EIM89673.1 - 3.7e-28 98.4 0.0 6.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EIM89673.1 - 5.4e-13 49.3 1.1 9.1e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein MSA-2c PF12238.8 EIM89673.1 - 0.35 10.9 2.7 0.5 10.3 2.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c PARP PF00644.20 EIM89674.1 - 2.6e-09 36.9 4.3 2.6e-07 30.4 0.0 2.8 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Perm-CXXC PF15629.6 EIM89674.1 - 0.61 10.4 4.7 0.99 9.7 4.7 1.3 1 0 0 1 1 1 0 Permuted single zf-CXXC unit DUF2321 PF10083.9 EIM89675.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) F-box-like PF12937.7 EIM89676.1 - 1.3e-07 31.4 0.2 6.8e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like Mto2_bdg PF12808.7 EIM89676.1 - 0.00091 19.5 0.7 0.0019 18.4 0.7 1.5 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region ZapB PF06005.12 EIM89676.1 - 0.0099 16.3 0.3 0.022 15.2 0.3 1.5 1 0 0 1 1 1 1 Cell division protein ZapB Shugoshin_N PF07558.11 EIM89676.1 - 0.025 14.5 0.3 0.049 13.5 0.3 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Glyco_hydro_3_C PF01915.22 EIM89677.1 - 1.6e-43 149.0 0.0 2.4e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM89677.1 - 8.6e-35 120.6 0.0 1.4e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM89677.1 - 1.9e-06 27.9 0.0 4.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PhoLip_ATPase_C PF16212.5 EIM89678.1 - 1.7e-71 240.9 23.8 1.7e-71 240.9 23.8 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIM89678.1 - 4e-16 58.5 6.0 1.6e-15 56.5 6.0 2.0 1 1 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EIM89678.1 - 8e-13 49.2 2.1 8.5e-06 26.2 0.1 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EIM89678.1 - 5.6e-07 29.3 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EIM89678.1 - 6.1e-07 29.4 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EIM89678.1 - 0.00016 21.5 0.6 0.0058 16.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 EIM89679.1 - 4.9e-11 42.3 1.5 4.9e-11 42.3 1.5 2.4 2 0 0 2 2 2 1 F-box-like DUF4470 PF14737.6 EIM89681.1 - 2.6e-08 34.0 0.0 7.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) DUF2786 PF10979.8 EIM89682.1 - 3.2e-10 39.7 3.5 3.2e-10 39.7 3.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Pam17 PF08566.10 EIM89683.1 - 7.8e-56 188.5 0.0 6.3e-43 146.5 0.0 2.0 1 1 0 2 2 2 2 Mitochondrial import protein Pam17 SNF2_N PF00176.23 EIM89684.1 - 3.5e-43 147.7 0.0 1.1e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM89684.1 - 5.9e-06 26.6 0.2 2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM89684.1 - 0.052 13.5 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit GPI-anchored PF10342.9 EIM89685.1 - 6e-05 23.7 0.0 7.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 EIM89685.1 - 0.074 12.8 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RHSP PF07999.11 EIM89686.1 - 0.00046 19.1 0.0 0.035 12.9 0.0 2.2 2 0 0 2 2 2 2 Retrotransposon hot spot protein AAA_7 PF12775.7 EIM89686.1 - 0.083 12.4 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region WD40 PF00400.32 EIM89687.1 - 1.1e-24 86.1 14.1 0.0015 19.4 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EIM89687.1 - 9.4e-13 47.8 1.7 2.1e-12 46.7 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM89687.1 - 4.4e-08 32.8 1.7 1.1e-07 31.5 1.7 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EIM89687.1 - 0.00028 19.7 0.0 0.13 10.9 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EIM89687.1 - 0.018 15.3 0.0 17 5.8 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIM89687.1 - 0.022 14.1 0.0 0.066 12.5 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain F-box_4 PF15966.5 EIM89687.1 - 0.093 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 F-box DUF4784 PF16023.5 EIM89687.1 - 0.22 10.4 0.0 3 6.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4784) SH3_9 PF14604.6 EIM89688.1 - 1.2e-07 31.4 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIM89688.1 - 7.6e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Apt1 PF10351.9 EIM89688.1 - 0.25 10.2 10.5 0.39 9.5 10.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain hSH3 PF14603.6 EIM89688.1 - 0.25 11.8 0.0 0.49 10.9 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain Hid1 PF12722.7 EIM89688.1 - 1.4 7.0 5.1 1.8 6.6 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4470 PF14737.6 EIM89690.1 - 2.3e-07 30.9 0.0 5.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EIM89690.1 - 0.00089 19.2 0.1 0.0066 16.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM89690.1 - 0.0046 17.6 0.2 0.0046 17.6 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89690.1 - 0.027 15.3 0.0 0.19 12.7 0.0 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF4727 PF15856.5 EIM89690.1 - 0.17 11.4 0.6 0.34 10.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) TPR_12 PF13424.6 EIM89690.1 - 0.31 11.3 1.9 17 5.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 EIM89692.1 - 2.7e-10 40.0 2.5 2.9e-10 39.9 0.4 2.2 2 0 0 2 2 2 1 F-box-like AAA_5 PF07728.14 EIM89693.1 - 6.7e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EIM89693.1 - 5.8e-09 36.3 0.0 1.3e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EIM89693.1 - 1.9e-06 28.4 0.0 4.8e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM89693.1 - 1.2e-05 25.6 0.0 6.2e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM89693.1 - 0.00078 19.9 0.0 0.037 14.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EIM89693.1 - 0.0035 17.7 0.0 0.0087 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EIM89693.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIM89693.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EIM89693.1 - 0.011 15.1 0.0 0.042 13.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.11 EIM89693.1 - 0.013 14.4 0.0 0.039 12.9 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain Ank_2 PF12796.7 EIM89693.1 - 0.018 15.6 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) AAA_33 PF13671.6 EIM89693.1 - 0.024 14.8 0.1 0.066 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EIM89693.1 - 0.026 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EIM89693.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EIM89693.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EIM89693.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 EIM89694.1 - 2.3e-07 30.6 2.2 1.1e-06 28.4 0.2 2.6 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.18 EIM89695.1 - 5.5e-10 39.2 17.0 1.1e-09 38.2 17.0 1.5 1 0 0 1 1 1 1 MYND finger TPR_19 PF14559.6 EIM89695.1 - 0.072 13.6 3.8 9.8 6.8 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM89695.1 - 0.25 12.2 3.9 16 6.6 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Dak1 PF02733.17 EIM89699.1 - 5.2e-86 288.4 0.6 9.1e-86 287.6 0.6 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EIM89699.1 - 6e-39 133.7 0.2 1.1e-38 132.9 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain Hydrolase PF00702.26 EIM89699.1 - 0.15 12.3 0.5 5.3 7.3 0.6 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase APH PF01636.23 EIM89700.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EIM89700.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain Epimerase PF01370.21 EIM89701.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MpPF26 PF07666.11 EIM89702.1 - 0.091 12.9 0.4 0.091 12.9 0.4 1.4 2 0 0 2 2 2 0 M penetrans paralogue family 26 tRNA_Me_trans PF03054.16 EIM89703.1 - 6.4e-120 400.2 0.0 7.3e-120 400.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EIM89703.1 - 0.053 12.6 0.1 1.8 7.7 0.1 2.4 2 1 0 2 2 2 0 NAD synthase TPP_enzyme_N PF02776.18 EIM89704.1 - 1.6e-54 184.1 0.1 1.1e-53 181.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EIM89704.1 - 1e-48 165.0 0.3 4.7e-47 159.6 0.3 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EIM89704.1 - 2.9e-39 134.0 0.9 6.4e-39 132.8 0.4 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Ank_4 PF13637.6 EIM89705.1 - 2.5e-07 31.1 0.6 0.0013 19.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EIM89705.1 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EIM89705.1 - 0.0054 17.3 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PCMT PF01135.19 EIM89705.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_3 PF13606.6 EIM89705.1 - 0.1 13.2 0.0 0.44 11.3 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat zf-MYND PF01753.18 EIM89708.1 - 1e-08 35.1 12.3 2e-08 34.2 12.3 1.5 1 0 0 1 1 1 1 MYND finger TPR_14 PF13428.6 EIM89708.1 - 6.4e-06 26.6 4.0 0.094 13.6 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM89708.1 - 0.00016 21.5 0.2 4.6 7.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM89708.1 - 0.005 17.5 0.5 21 5.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM89708.1 - 0.037 13.9 0.1 33 4.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIM89708.1 - 0.081 13.0 0.2 28 5.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIM89708.1 - 0.087 13.4 5.2 0.97 10.0 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM89708.1 - 0.14 12.5 3.3 32 4.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP1_OBG PF01018.22 EIM89709.1 - 7.2e-41 139.4 1.4 3e-30 104.9 0.8 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EIM89709.1 - 1.2e-18 67.3 0.0 2.7e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EIM89709.1 - 3.4e-05 23.0 1.1 0.048 12.6 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EIM89709.1 - 0.0002 21.0 0.0 0.00043 19.8 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 EIM89709.1 - 0.00036 20.1 0.1 0.01 15.5 0.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EIM89709.1 - 0.0027 17.3 0.4 0.056 13.0 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EIM89709.1 - 0.0037 17.3 0.0 0.015 15.3 0.0 2.2 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 EIM89709.1 - 0.0039 17.7 0.0 0.014 15.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Arf PF00025.21 EIM89709.1 - 0.0068 15.9 0.2 1.8 8.0 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_18 PF13238.6 EIM89709.1 - 0.017 15.6 0.1 0.068 13.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain Lpp-LpqN PF10738.9 EIM89709.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Probable lipoprotein LpqN AAA_21 PF13304.6 EIM89709.1 - 0.29 10.9 1.2 8.7 6.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RRM_3 PF08777.11 EIM89710.1 - 0.011 15.8 0.0 0.065 13.3 0.0 2.3 1 1 0 1 1 1 0 RNA binding motif RRM_1 PF00076.22 EIM89710.1 - 0.025 14.4 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C12 PF01088.21 EIM89711.1 - 1.9e-55 187.9 0.0 2.2e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Tim54 PF11711.8 EIM89712.1 - 2.4e-57 194.4 0.0 3.1e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.16 EIM89713.1 - 1.4e-25 90.0 0.0 3.5e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 EIM89713.1 - 8e-22 77.8 0.1 2.4e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM89713.1 - 3.4e-09 36.9 0.0 7.7e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM89713.1 - 7.6e-08 32.7 0.2 9.2e-07 29.2 0.2 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EIM89713.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EIM89713.1 - 0.11 12.8 0.0 0.6 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain CKS PF01111.19 EIM89714.1 - 2.3e-35 120.7 0.3 3.2e-35 120.2 0.3 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3822 PF12864.7 EIM89714.1 - 0.0019 17.4 0.1 0.0023 17.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3822) Cerato-platanin PF07249.12 EIM89715.1 - 1.6e-42 144.4 1.7 1.9e-42 144.1 1.7 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 EIM89715.1 - 0.0023 17.8 0.3 0.0036 17.1 0.3 1.3 1 1 0 1 1 1 1 Barwin family Asp PF00026.23 EIM89716.1 - 1.1e-80 271.4 9.9 1.4e-80 271.1 9.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM89716.1 - 1e-08 35.6 6.9 7.7e-06 26.3 6.9 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EIM89716.1 - 0.0064 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF1918 PF08940.11 EIM89716.1 - 0.078 12.6 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Asp PF00026.23 EIM89717.1 - 1e-81 274.8 13.4 1.2e-81 274.6 13.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM89717.1 - 8.7e-09 35.9 9.4 0.00024 21.4 0.7 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EIM89717.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF1918 PF08940.11 EIM89717.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) NUDIX PF00293.28 EIM89718.1 - 1.8e-10 40.9 0.0 3.3e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Herpes_TAF50 PF03326.13 EIM89718.1 - 0.01 14.5 0.1 0.019 13.6 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Glyco_hydro_18 PF00704.28 EIM89719.1 - 2e-24 86.9 0.2 9.2e-24 84.7 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_35 PF01301.19 EIM89720.1 - 1.8e-80 270.9 1.7 2.5e-80 270.5 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EIM89720.1 - 1.1e-55 187.0 6.1 6.1e-33 113.8 0.1 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EIM89720.1 - 4.4e-34 117.9 3.9 8.2e-34 117.0 3.9 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EIM89720.1 - 9.7e-18 63.5 2.8 4.6e-17 61.4 0.1 3.0 2 1 1 3 3 3 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 EIM89720.1 - 0.00077 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PerB PF06590.11 EIM89720.1 - 0.07 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 PerB protein UL45 PF05473.12 EIM89722.1 - 0.0083 15.8 0.2 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like MARVEL PF01284.23 EIM89722.1 - 0.037 14.1 15.3 0.14 12.2 15.2 2.3 1 1 0 1 1 1 0 Membrane-associating domain DUF5083 PF16890.5 EIM89722.1 - 0.18 11.5 1.6 13 5.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5083) SCAMP PF04144.13 EIM89722.1 - 1.3 9.3 14.2 2.5 8.4 14.2 1.5 1 1 0 1 1 1 0 SCAMP family Peptidase_M16_M PF16187.5 EIM89723.1 - 1.9e-91 306.2 0.0 8.8e-91 304.1 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EIM89723.1 - 2.4e-37 128.2 0.2 1.2e-36 125.9 0.1 2.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EIM89723.1 - 1.4e-22 80.6 0.0 1.5e-10 41.4 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain ANAPC4_WD40 PF12894.7 EIM89724.1 - 0.0035 17.6 0.0 1.2 9.5 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM89724.1 - 0.013 16.3 1.2 2.9 8.9 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat PRKG1_interact PF15898.5 EIM89724.1 - 0.43 11.5 7.5 0.14 13.0 1.4 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 EIM89724.1 - 6.2 7.3 7.7 0.28 11.6 1.9 1.7 2 0 0 2 2 2 0 Cell division protein ZapB SKIP_SNW PF02731.15 EIM89725.1 - 1.3e-72 242.8 1.1 1.3e-72 242.8 1.1 2.2 2 0 0 2 2 2 1 SKIP/SNW domain ALAD PF00490.21 EIM89726.1 - 1.4e-120 402.3 0.0 1.7e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MRJP PF03022.16 EIM89727.1 - 4.6e-29 101.7 0.0 1.3e-28 100.2 0.0 1.6 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 EIM89727.1 - 0.00017 21.2 0.0 0.00079 19.1 0.0 2.1 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Septin PF00735.18 EIM89729.1 - 3.4e-115 384.2 0.7 4.1e-115 383.9 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EIM89729.1 - 7.3e-09 35.7 0.2 2.1e-08 34.2 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM89729.1 - 1.5e-06 28.2 0.2 2.3e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EIM89729.1 - 1.6e-06 27.6 0.0 3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EIM89729.1 - 1e-05 25.2 0.4 0.00059 19.4 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EIM89729.1 - 4.6e-05 23.5 0.5 0.13 12.3 0.1 2.5 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.27 EIM89729.1 - 0.00011 22.7 0.1 0.00052 20.5 0.1 2.0 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 EIM89729.1 - 0.0005 19.3 0.0 0.00099 18.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 EIM89729.1 - 0.0017 17.9 0.3 0.026 14.0 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EIM89729.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 EIM89729.1 - 0.0024 17.3 0.7 0.016 14.6 0.7 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EIM89729.1 - 0.0054 17.1 0.0 0.0082 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EIM89729.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Roc PF08477.13 EIM89729.1 - 0.018 15.2 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EIM89729.1 - 0.019 14.1 0.1 0.1 11.7 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EIM89729.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIM89729.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 EIM89729.1 - 0.037 13.6 0.3 0.53 9.9 0.0 2.6 2 2 0 2 2 2 0 Ras family DUF815 PF05673.13 EIM89729.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 EIM89729.1 - 0.073 12.2 1.0 0.63 9.1 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 EIM89729.1 - 0.083 12.9 0.1 0.4 10.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 EIM89729.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 EIM89729.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1217 PF06748.12 EIM89729.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1217) GPS2_interact PF15784.5 EIM89731.1 - 0.16 12.4 0.3 0.34 11.4 0.3 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain EHN PF06441.12 EIM89732.1 - 2.3e-33 114.8 0.7 5.4e-32 110.4 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EIM89732.1 - 2e-12 47.3 0.1 3.4e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM89732.1 - 0.0065 17.1 6.6 0.0065 17.1 6.6 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family VRR_NUC PF08774.11 EIM89733.1 - 6.2e-25 87.4 0.1 1.6e-24 86.1 0.1 1.7 1 0 0 1 1 1 1 VRR-NUC domain F-box-like PF12937.7 EIM89735.1 - 1.1e-08 34.8 0.5 1.1e-08 34.8 0.5 2.6 2 1 0 2 2 2 1 F-box-like Cyclin_N PF00134.23 EIM89736.1 - 2.5e-09 36.9 0.0 5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EIM89736.1 - 1.4e-07 32.1 0.1 1.4e-07 32.1 0.1 1.8 2 0 0 2 2 2 1 Cyclin zf-C4H2 PF10146.9 EIM89737.1 - 3e-07 31.0 1.7 3.6e-07 30.7 1.7 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Vps5 PF09325.10 EIM89737.1 - 0.0018 17.9 2.6 0.0027 17.3 2.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like DUF4047 PF13256.6 EIM89737.1 - 0.015 15.5 0.7 0.015 15.5 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Latarcin PF10279.9 EIM89737.1 - 0.036 14.5 1.7 0.036 14.5 1.7 1.6 2 0 0 2 2 2 0 Latarcin precursor DUF3450 PF11932.8 EIM89737.1 - 0.055 12.8 5.3 0.098 11.9 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Peptidase_S46 PF10459.9 EIM89737.1 - 0.25 10.0 6.5 0.28 9.8 6.5 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF4337 PF14235.6 EIM89737.1 - 0.51 10.4 4.9 0.9 9.6 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) COG2 PF06148.11 EIM89737.1 - 1 9.4 6.0 0.66 10.1 3.3 1.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 EIM89737.1 - 1.5 8.1 8.1 2 7.7 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 EIM89737.1 - 1.5 8.0 3.9 1.8 7.7 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein JIP_LZII PF16471.5 EIM89737.1 - 2 8.6 9.3 1.7 8.9 7.0 2.0 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 EIM89737.1 - 6.5 5.5 13.4 3.2 6.6 7.0 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein His_Phos_2 PF00328.22 EIM89738.1 - 7.8e-25 88.0 0.0 9.8e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MMM1 PF10296.9 EIM89739.1 - 1.2e-09 37.7 0.0 1.1e-05 24.6 0.0 3.0 3 0 0 3 3 3 3 Maintenance of mitochondrial morphology protein 1 FliJ PF02050.16 EIM89740.1 - 0.00079 19.6 11.1 0.00079 19.6 11.1 2.6 3 1 0 3 3 3 1 Flagellar FliJ protein Bcr-Abl_Oligo PF09036.10 EIM89740.1 - 0.094 12.7 1.9 3.9 7.6 0.5 2.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 EIM89740.1 - 0.51 9.2 13.1 0.032 13.1 6.9 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 EIM89740.1 - 1.3 9.1 10.5 0.42 10.7 3.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 EIM89740.1 - 7.5 7.0 19.7 75 3.7 0.2 3.1 2 1 0 2 2 2 0 Fez1 IML1 PF12257.8 EIM89743.1 - 1.4e-112 375.5 0.0 2e-112 375.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EIM89743.1 - 3.9e-19 68.5 0.1 7.2e-19 67.6 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MazE_antitoxin PF04014.18 EIM89743.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Acetyltransf_1 PF00583.25 EIM89744.1 - 2.3e-09 37.5 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM89744.1 - 1e-06 28.7 0.1 1.5e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM89744.1 - 2.9e-06 27.6 0.1 5.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM89744.1 - 0.00016 21.6 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EIM89744.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM89744.1 - 0.037 14.1 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.7 EIM89745.1 - 6.2e-10 38.8 2.1 1.3e-09 37.7 2.1 1.6 1 0 0 1 1 1 1 F-box-like An_peroxidase PF03098.15 EIM89745.1 - 0.0022 16.7 0.5 0.004 15.8 0.0 1.6 2 0 0 2 2 2 1 Animal haem peroxidase F-box PF00646.33 EIM89745.1 - 0.02 14.8 0.7 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 F-box domain HEPN_AbiU2 PF18734.1 EIM89745.1 - 0.058 12.9 0.1 8 5.9 0.0 2.2 2 0 0 2 2 2 0 AbiU2 NTP_transferase PF00483.23 EIM89746.1 - 2.5e-39 135.4 0.0 7.1e-39 133.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EIM89746.1 - 1.9e-05 25.1 0.1 4.8e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 EIM89746.1 - 5e-05 23.2 0.1 8.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Radical_SAM_C PF16199.5 EIM89747.1 - 3.6e-30 103.8 0.0 7e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EIM89747.1 - 3.2e-17 63.4 0.1 1.3e-16 61.5 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EIM89747.1 - 4.7e-09 36.5 0.1 1.2e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM89747.1 - 2.6e-06 27.4 0.0 6.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM89747.1 - 0.0015 18.9 0.0 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM89747.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein GDA1_CD39 PF01150.17 EIM89748.1 - 1.1e-107 360.4 0.0 1.4e-106 356.7 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EIM89748.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Fungal_trans PF04082.18 EIM89751.1 - 7e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM89751.1 - 2.1e-05 24.5 8.4 3.8e-05 23.7 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_18 PF13512.6 EIM89751.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Cupin_1 PF00190.22 EIM89752.1 - 7.5e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EIM89752.1 - 5.7e-06 26.0 0.4 3.2e-05 23.6 0.4 2.0 1 1 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EIM89752.1 - 0.028 14.3 0.1 0.049 13.5 0.1 1.4 1 1 0 1 1 1 0 AraC-like ligand binding domain PhyH PF05721.13 EIM89752.1 - 0.04 14.2 0.1 0.058 13.7 0.1 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Cupin_6 PF12852.7 EIM89752.1 - 0.065 12.9 0.0 0.087 12.5 0.0 1.3 1 1 0 1 1 1 0 Cupin ARD PF03079.14 EIM89752.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family WD40 PF00400.32 EIM89753.1 - 1.1e-40 136.8 25.1 2.8e-06 27.9 0.1 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EIM89753.1 - 2.9e-11 43.1 1.0 6.5e-11 42.0 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM89753.1 - 1.2e-09 37.8 0.1 1.2e-09 37.8 0.1 2.5 2 1 1 3 3 3 1 F-box domain ANAPC4_WD40 PF12894.7 EIM89753.1 - 3.5e-06 27.2 0.2 8.6 6.7 0.0 5.8 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM89753.1 - 1.4e-05 23.9 10.8 0.09 11.4 0.1 5.5 3 1 2 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EIM89753.1 - 0.16 10.7 0.5 8.3 5.0 0.0 3.3 2 2 1 3 3 3 0 Nup133 N terminal like YL1 PF05764.13 EIM89753.1 - 0.28 11.3 3.4 0.54 10.3 3.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein PALB2_WD40 PF16756.5 EIM89753.1 - 1.2 7.9 8.1 1.9 7.3 0.8 3.4 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain zf-C3HC4_3 PF13920.6 EIM89754.1 - 2e-09 37.2 16.7 2e-09 37.2 16.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM89754.1 - 0.08 12.8 16.0 0.15 11.9 16.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PLDc_2 PF13091.6 EIM89755.1 - 3.7e-11 43.1 0.0 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EIM89755.1 - 3e-07 30.3 0.1 0.024 14.8 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Tyr_Deacylase PF02580.16 EIM89756.1 - 2.6e-53 180.4 0.0 3.3e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase WD40 PF00400.32 EIM89757.1 - 2e-39 132.9 29.4 1.2e-05 25.9 0.0 8.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89757.1 - 3.3e-07 30.5 0.9 6.1 7.2 0.0 5.9 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM89757.1 - 0.00014 20.6 10.1 0.22 10.1 0.2 5.5 2 2 3 6 6 6 2 Nucleoporin Nup120/160 F-box PF00646.33 EIM89757.1 - 0.00016 21.5 1.4 0.00027 20.7 1.4 1.4 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.11 EIM89757.1 - 0.026 13.3 4.2 4.8 5.8 0.0 4.1 2 2 2 4 4 4 0 Nup133 N terminal like F-box-like PF12937.7 EIM89757.1 - 0.028 14.3 2.2 0.053 13.4 2.2 1.5 1 0 0 1 1 1 0 F-box-like PQQ_3 PF13570.6 EIM89757.1 - 0.082 13.4 0.1 20 5.8 0.0 3.5 2 0 0 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 EIM89757.1 - 0.27 10.1 7.7 0.86 8.5 0.9 3.6 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Pro_isomerase PF00160.21 EIM89758.1 - 8.3e-53 178.9 0.0 9.2e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.7 EIM89759.1 - 6.1e-07 29.2 1.7 1.8e-06 27.8 1.7 1.9 1 0 0 1 1 1 1 F-box-like Nuc_sug_transp PF04142.15 EIM89760.1 - 2e-96 322.8 11.7 7.6e-96 321.0 11.7 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EIM89760.1 - 6.7e-05 23.1 2.1 6.7e-05 23.1 2.1 2.8 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 EIM89760.1 - 0.0058 16.0 2.3 0.0058 16.0 2.3 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 EIM89760.1 - 0.02 14.1 14.0 0.038 13.2 14.0 1.4 1 1 0 1 1 1 0 UAA transporter family PUNUT PF16913.5 EIM89760.1 - 0.35 10.1 13.4 0.88 8.7 13.4 1.8 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Mit_ribos_Mrp51 PF11709.8 EIM89761.1 - 1.4e-15 57.8 8.8 2.1e-13 50.6 8.8 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit AAA_12 PF13087.6 EIM89763.1 - 1.6e-44 151.9 0.0 2.5e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EIM89763.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ribosomal_S13_N PF08069.12 EIM89763.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Rep_fac-A_C PF08646.10 EIM89766.1 - 2.2e-50 170.2 3.2 7.7e-50 168.4 0.5 2.5 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EIM89766.1 - 4.8e-37 125.8 0.4 2.2e-36 123.7 0.1 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EIM89766.1 - 2.7e-23 81.9 2.1 2.7e-23 81.9 0.5 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EIM89766.1 - 3e-13 49.6 0.5 2.5e-11 43.4 0.1 2.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 EIM89766.1 - 2.9e-07 28.8 1.7 0.00027 19.0 0.1 2.4 2 1 0 2 2 2 2 Family of unknown function (DUF5521) DUF4539 PF15072.6 EIM89766.1 - 0.11 12.6 0.1 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) PLATZ PF04640.14 EIM89766.1 - 0.4 11.3 2.3 0.78 10.4 0.0 2.6 3 0 0 3 3 3 0 PLATZ transcription factor IDO PF01231.18 EIM89767.1 - 4.2e-113 378.4 0.0 7.8e-113 377.5 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase ECH_2 PF16113.5 EIM89768.1 - 5e-113 378.0 0.0 8.5e-113 377.2 0.0 1.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EIM89768.1 - 4.5e-24 85.1 0.0 6.9e-23 81.2 0.0 2.2 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase CAP_GLY PF01302.25 EIM89769.1 - 4.6e-20 71.4 0.2 7.2e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 EIM89769.1 - 3.5e-09 36.3 9.5 4.5e-06 26.3 0.6 4.7 3 1 2 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EIM89769.1 - 1e-08 35.3 13.1 0.0039 17.6 2.1 5.7 2 2 5 7 7 7 4 Leucine Rich repeats (2 copies) FNIP PF05725.12 EIM89769.1 - 0.033 14.4 1.3 0.69 10.1 0.0 3.6 2 1 1 3 3 3 0 FNIP Repeat LRR_6 PF13516.6 EIM89769.1 - 2.1 8.6 10.6 36 4.8 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich repeat Aminotran_5 PF00266.19 EIM89770.1 - 1.8e-93 313.5 0.0 2.1e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EIM89770.1 - 5.4e-08 32.5 0.1 8.3e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EIM89770.1 - 1.8e-05 24.2 0.2 0.00023 20.6 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EIM89770.1 - 0.00053 18.6 0.0 0.00079 18.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 EIM89771.1 - 3.3e-29 100.5 0.0 1e-17 63.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIM89771.1 - 7.1e-05 22.4 0.0 0.045 13.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIM89771.1 - 0.00016 21.6 0.0 0.0019 18.2 0.0 2.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EIM89771.1 - 0.00083 19.4 0.0 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 EIM89771.1 - 0.0098 16.0 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 DbpA PF03880.15 EIM89771.1 - 0.02 14.9 0.0 8.7 6.4 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Tet_JBP PF12851.7 EIM89775.1 - 0.073 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Glyco_hydro_6 PF01341.17 EIM89776.1 - 1.3e-107 360.1 2.2 1.6e-107 359.8 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EIM89776.1 - 3.1e-12 46.2 11.8 7.1e-12 45.1 11.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1681 PF07933.14 EIM89777.1 - 1.9e-53 180.1 0.0 2.2e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.12 EIM89777.1 - 0.0065 14.8 0.0 0.0077 14.6 0.0 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus NIF PF03031.18 EIM89778.1 - 1.3e-20 73.7 0.0 2.3e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EIM89778.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Acid_phosphat_B PF03767.14 EIM89778.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) NUDIX PF00293.28 EIM89779.1 - 6.6e-13 48.8 0.1 3.7e-12 46.4 0.0 2.2 2 1 0 2 2 2 1 NUDIX domain NUDIX_4 PF14815.6 EIM89779.1 - 0.00061 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain YL1 PF05764.13 EIM89781.1 - 0.005 17.0 0.5 0.0066 16.6 0.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein TFIIF_alpha PF05793.12 EIM89781.1 - 0.018 13.6 5.6 0.026 13.2 5.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aminotran_1_2 PF00155.21 EIM89782.1 - 4.3e-31 108.4 0.0 4.9e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.18 EIM89783.1 - 4.1e-10 39.6 10.6 7.6e-10 38.8 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cwf_Cwc_15 PF04889.12 EIM89784.1 - 0.0087 15.8 8.7 0.011 15.5 8.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-T_N PF16171.5 EIM89784.1 - 0.17 10.7 5.9 0.23 10.3 5.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus Pex14_N PF04695.13 EIM89784.1 - 0.4 11.3 6.3 1.2 9.7 5.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_Ag35 PF03286.14 EIM89784.1 - 0.98 9.2 9.5 1.6 8.5 9.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EIM89784.1 - 2.3 7.4 11.7 3.1 7.0 11.7 1.1 1 0 0 1 1 1 0 NOA36 protein K_channel_TID PF07941.11 EIM89784.1 - 2.6 8.6 7.9 0.41 11.1 3.1 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PPP4R2 PF09184.11 EIM89784.1 - 3.7 7.0 13.9 5.5 6.5 13.9 1.2 1 0 0 1 1 1 0 PPP4R2 Spt20 PF12090.8 EIM89784.1 - 3.9 7.0 14.0 5.5 6.5 14.0 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 EIM89784.1 - 3.9 6.2 11.5 4.9 5.9 11.5 1.1 1 0 0 1 1 1 0 Androgen receptor CwfJ_C_1 PF04677.15 EIM89785.1 - 5.7e-30 103.7 0.0 1.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 EIM89785.1 - 6.6e-24 83.4 29.1 1.9e-10 40.3 0.8 3.7 4 0 0 4 4 4 3 Zinc knuckle CwfJ_C_2 PF04676.14 EIM89785.1 - 1.3e-12 48.5 0.0 2.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 EIM89785.1 - 7.6e-09 35.3 10.4 0.014 15.4 0.1 3.8 3 0 0 3 3 3 3 Zinc knuckle DUF4428 PF14471.6 EIM89785.1 - 0.015 15.2 0.9 1.8 8.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.16 EIM89785.1 - 3.1 8.1 4.7 2.7 8.2 1.4 2.3 1 1 0 2 2 2 0 FYVE-type zinc finger zinc-ribbons_6 PF07191.12 EIM89785.1 - 9.8 6.2 9.2 59 3.7 3.3 2.8 1 1 1 2 2 2 0 zinc-ribbons COesterase PF00135.28 EIM89787.1 - 4.6e-63 213.9 0.0 5.6e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM89787.1 - 8.3e-11 42.1 0.1 1.6e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cupin_1 PF00190.22 EIM89788.1 - 8.6e-42 142.3 0.0 1.4e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EIM89788.1 - 1.6e-30 104.7 0.9 3.3e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EIM89788.1 - 5.3e-10 38.8 0.1 6.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) ARD PF03079.14 EIM89788.1 - 2.6e-06 27.7 0.0 0.0044 17.2 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family MannoseP_isomer PF01050.18 EIM89788.1 - 7.8e-06 25.8 0.0 0.0008 19.3 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EIM89788.1 - 8.7e-06 25.7 0.4 0.00021 21.2 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_4 PF08007.12 EIM89788.1 - 4.5e-05 23.1 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein 3-HAO PF06052.12 EIM89788.1 - 0.0023 17.6 0.0 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.6 EIM89788.1 - 0.041 13.6 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Cupin-like domain Pirin_C PF05726.13 EIM89788.1 - 0.05 14.0 0.0 0.76 10.2 0.0 2.2 2 0 0 2 2 2 0 Pirin C-terminal cupin domain Cytomega_UL20A PF05984.12 EIM89788.1 - 0.071 13.4 0.4 0.13 12.6 0.4 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein DUF2291 PF10054.9 EIM89788.1 - 0.12 12.0 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF3446 PF11928.8 EIM89788.1 - 0.75 10.1 8.7 2.4 8.5 8.7 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain Acyl-CoA_dh_1 PF00441.24 EIM89790.1 - 4e-41 140.7 1.2 4.7e-41 140.5 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EIM89790.1 - 1.5e-38 131.9 0.0 2.8e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EIM89790.1 - 1.1e-24 86.5 0.0 2e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIM89790.1 - 2.5e-15 56.9 0.0 4.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EIM89790.1 - 0.1 13.2 0.0 0.31 11.6 0.0 1.9 2 1 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DUF5340 PF17275.2 EIM89791.1 - 0.11 12.7 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5340) Ins_P5_2-kin PF06090.12 EIM89792.1 - 6.9e-77 259.1 0.0 8.2e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase adh_short_C2 PF13561.6 EIM89793.1 - 1.1e-57 195.2 0.1 1.4e-57 194.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM89793.1 - 4.8e-43 146.9 0.1 8.3e-43 146.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM89793.1 - 1.5e-10 41.2 0.1 2.6e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM89793.1 - 6.8e-05 22.5 0.0 0.00052 19.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EIM89793.1 - 0.0032 16.6 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 EIM89793.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 ThiF family GDP_Man_Dehyd PF16363.5 EIM89793.1 - 0.14 11.6 0.0 6 6.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase GATA PF00320.27 EIM89794.1 - 4.1e-15 55.1 5.3 6.7e-15 54.4 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.7 EIM89794.1 - 0.00077 19.7 0.0 0.0024 18.1 0.0 1.9 1 1 1 2 2 2 1 PAS domain PAS PF00989.25 EIM89794.1 - 0.00099 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EIM89794.1 - 0.0038 17.5 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 EIM89794.1 - 0.018 15.1 1.0 0.05 13.7 0.2 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Adeno_shaft PF00608.17 EIM89794.1 - 0.06 13.2 0.3 0.099 12.5 0.3 1.3 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Lactococcin_972 PF09683.10 EIM89794.1 - 0.2 12.2 0.3 0.2 12.2 0.3 1.8 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) TFR_dimer PF04253.15 EIM89795.1 - 1.7e-19 70.1 0.8 1.3e-17 64.0 0.0 2.4 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EIM89795.1 - 6.3e-14 52.1 0.0 1.8e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EIM89795.1 - 2.6e-08 33.8 0.1 6.4e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EIM89795.1 - 0.11 12.1 0.1 0.39 10.4 0.1 1.8 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 TFR_dimer PF04253.15 EIM89796.1 - 1.5e-20 73.5 0.3 1.4e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EIM89796.1 - 1.9e-15 57.1 0.0 5e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EIM89796.1 - 2e-08 34.1 0.3 4.6e-08 33.0 0.3 1.7 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EIM89796.1 - 0.035 13.8 0.0 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 IMS PF00817.20 EIM89797.1 - 4.5e-40 137.1 0.0 7.5e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EIM89797.1 - 8.5e-13 49.0 0.0 5.4e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EIM89797.1 - 1.6e-06 27.6 1.4 0.00078 19.0 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EIM89797.1 - 0.022 15.1 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif YTH PF04146.15 EIM89798.1 - 1.1e-39 136.0 0.1 2.5e-39 134.9 0.1 1.6 1 0 0 1 1 1 1 YT521-B-like domain F-box-like PF12937.7 EIM89799.1 - 3.5e-08 33.2 3.8 1.6e-07 31.1 3.8 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM89800.1 - 5.2e-10 39.0 0.0 8.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM89800.1 - 0.00052 19.8 0.9 0.23 11.4 0.1 2.4 2 0 0 2 2 2 2 F-box domain DASH_Dad3 PF08656.10 EIM89801.1 - 2.2e-22 78.9 0.0 2.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 TIMELESS_C PF05029.13 EIM89802.1 - 0.044 12.9 4.2 0.057 12.6 4.2 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region CAF1A PF12253.8 EIM89802.1 - 0.08 13.1 5.9 0.17 12.1 5.9 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A PTPRCAP PF15713.5 EIM89802.1 - 0.23 11.8 5.8 0.37 11.1 5.2 1.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF5571 PF17732.1 EIM89802.1 - 2.5 7.5 7.9 3.6 7.0 7.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5571) Pkinase PF00069.25 EIM89803.1 - 6.1e-53 179.9 0.0 7.7e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89803.1 - 4.4e-20 72.1 0.0 6.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM89803.1 - 5.9e-05 22.5 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM89803.1 - 0.0066 16.4 0.4 0.015 15.2 0.4 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EIM89803.1 - 0.2 11.3 0.1 22 4.6 0.0 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EIM89803.1 - 0.43 9.3 0.0 0.43 9.3 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase WD40 PF00400.32 EIM89804.1 - 4e-14 52.8 17.8 5e-05 24.0 0.1 7.1 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89804.1 - 4.6e-10 39.7 0.0 0.0019 18.4 0.0 4.1 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 EIM89804.1 - 4.5e-05 22.4 2.0 0.00092 18.1 0.5 2.7 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 EIM89804.1 - 0.034 14.0 0.1 1.7 8.5 0.0 2.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A M_domain PF12938.7 EIM89804.1 - 0.33 10.7 1.9 0.53 10.1 1.9 1.3 1 0 0 1 1 1 0 M domain of GW182 Arginase PF00491.21 EIM89805.1 - 4.6e-76 256.0 0.1 5.4e-76 255.8 0.1 1.0 1 0 0 1 1 1 1 Arginase family PFU PF09070.11 EIM89806.1 - 1.7e-39 134.6 0.0 3.2e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 EIM89806.1 - 2.8e-36 125.2 0.4 3.9e-36 124.7 0.4 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 EIM89806.1 - 1.4e-27 95.4 9.3 7.4e-05 23.4 0.5 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 EIM89806.1 - 0.00049 20.1 0.0 0.026 14.5 0.0 3.0 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Endomucin PF07010.12 EIM89807.1 - 0.13 12.2 0.3 0.27 11.2 0.3 1.4 1 0 0 1 1 1 0 Endomucin DUF2721 PF11026.8 EIM89807.1 - 1.9 8.4 8.4 0.34 10.8 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) HlyIII PF03006.20 EIM89807.1 - 5 6.8 10.4 2.7 7.7 1.1 2.4 1 1 2 3 3 3 0 Haemolysin-III related LPG_synthase_TM PF03706.13 EIM89807.1 - 5.2 6.5 13.3 1.9 7.9 7.6 2.3 1 1 1 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Gtr1_RagA PF04670.12 EIM89808.1 - 1.1e-83 280.1 0.0 2.2e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EIM89808.1 - 2.4e-07 31.0 0.0 5.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIM89808.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EIM89808.1 - 7e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EIM89808.1 - 0.00046 19.7 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EIM89808.1 - 0.021 14.5 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EIM89808.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EIM89808.1 - 0.35 10.0 1.8 12 4.9 0.5 2.5 2 1 1 3 3 3 0 G-protein alpha subunit DMRL_synthase PF00885.19 EIM89809.1 - 2.3e-57 192.8 0.0 3e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.12 EIM89810.1 - 9.3e-28 96.9 3.5 9.3e-28 96.9 3.5 2.3 3 0 0 3 3 3 1 SRP40, C-terminal domain Brix PF04427.18 EIM89811.1 - 2.6e-37 128.8 0.0 3.3e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 EIM89811.1 - 0.16 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin Na_Ca_ex PF01699.24 EIM89813.1 - 1.4e-40 138.8 29.9 1.4e-20 73.7 16.5 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein His_Phos_2 PF00328.22 EIM89814.1 - 8.1e-54 183.4 0.0 9.7e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1776 PF08643.10 EIM89815.1 - 8.8e-17 61.4 0.0 1.3e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF883 PF05957.13 EIM89815.1 - 0.005 17.4 3.4 0.025 15.2 0.3 2.9 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF883) DUF1180 PF06679.12 EIM89815.1 - 1.2 9.5 6.1 0.69 10.3 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CPDase PF07823.11 EIM89816.1 - 2.9e-16 59.8 0.0 8.1e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EIM89816.1 - 3.7e-05 23.7 0.0 0.00046 20.1 0.0 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3278 PF11683.8 EIM89819.1 - 0.19 11.8 0.1 0.3 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) WD40 PF00400.32 EIM89820.1 - 6e-30 102.8 18.0 4.2e-07 30.6 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM89820.1 - 6.5e-10 39.2 3.4 0.11 12.8 0.2 4.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EIM89820.1 - 0.25 10.2 1.3 15 4.4 0.1 3.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Elongin_A PF06881.11 EIM89821.1 - 9.6e-17 61.4 0.1 1.7e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Gti1_Pac2 PF09729.9 EIM89823.1 - 1.9e-29 103.0 0.1 1.1e-26 94.0 0.2 2.2 1 1 0 2 2 2 2 Gti1/Pac2 family cwf18 PF08315.12 EIM89824.1 - 7.3e-36 123.8 12.3 8.6e-36 123.6 12.3 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SIR4_SID PF16991.5 EIM89824.1 - 0.12 12.4 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Sir4 SID domain GTP_EFTU PF00009.27 EIM89825.1 - 2e-52 177.6 0.0 3.3e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EIM89825.1 - 3.8e-43 146.0 0.2 8.4e-43 144.9 0.2 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EIM89825.1 - 1.1e-17 63.8 0.0 2.4e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EIM89825.1 - 2.8e-10 40.4 0.1 6.8e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM89825.1 - 1.7e-06 28.1 0.1 4.7e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EIM89825.1 - 4.7e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 EIM89825.1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 EIM89825.1 - 0.00024 21.1 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EIM89825.1 - 0.0075 15.7 0.1 0.041 13.3 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EIM89825.1 - 0.024 14.6 0.1 0.72 9.7 0.0 2.4 1 1 1 2 2 2 0 RsgA GTPase Septin PF00735.18 EIM89825.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin IF-2B PF01008.17 EIM89826.1 - 2.2e-63 214.1 0.0 2.6e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyt_c_ox_IV PF12270.8 EIM89826.1 - 0.087 13.0 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Trp_syntA PF00290.20 EIM89827.1 - 2.2e-85 285.6 0.5 3.1e-85 285.2 0.5 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EIM89827.1 - 8.3e-47 160.0 0.2 1.3e-46 159.4 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 EIM89827.1 - 0.00024 20.7 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 EIM89827.1 - 0.00033 20.2 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Asparaginase PF00710.20 EIM89828.1 - 2.2e-57 193.7 0.0 1.2e-56 191.4 0.0 2.1 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EIM89828.1 - 5.2e-29 100.8 0.0 1.2e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EIM89828.1 - 2.3e-11 44.1 0.0 6.9e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIM89828.1 - 1.7e-08 34.0 0.2 0.019 15.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EIM89828.1 - 5.8e-08 32.8 0.5 0.014 15.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EIM89828.1 - 1.2e-07 31.9 0.2 6.8e-07 29.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIM89828.1 - 8.2e-07 29.5 0.2 3.7e-05 24.2 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Csm1 PF12539.8 EIM89829.1 - 0.00068 20.2 0.0 0.0017 19.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 CEP63 PF17045.5 EIM89829.1 - 4 7.3 27.3 4.3 7.2 12.4 2.2 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF1515 PF07439.11 EIM89829.1 - 7 6.7 7.7 1.3 9.1 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) KH_1 PF00013.29 EIM89830.1 - 1e-43 147.0 7.2 5.4e-16 58.2 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EIM89830.1 - 1.6e-14 53.5 6.8 2.6e-05 24.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EIM89830.1 - 5.8e-06 26.1 1.7 0.068 13.1 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 EIM89830.1 - 0.00023 21.2 5.2 0.63 10.2 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 EIM89830.1 - 0.079 13.0 0.0 6.6 6.8 0.0 3.1 3 0 0 3 3 3 0 KH-like RNA-binding domain POT1 PF02765.17 EIM89831.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.7 1 1 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DUF2054 PF10218.9 EIM89831.1 - 0.019 15.0 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) DUF234 PF03008.14 EIM89831.1 - 0.21 12.0 0.3 3.4 8.2 0.0 2.6 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function UCH PF00443.29 EIM89832.1 - 2.3e-36 125.6 0.3 4e-36 124.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM89832.1 - 2e-16 60.5 2.3 2e-16 60.5 2.3 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EIM89832.1 - 4.1e-07 29.7 0.2 8.5e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 EIM89832.1 - 4.1e-06 27.3 0.0 0.22 12.1 0.0 3.0 2 0 0 2 2 2 2 DUSP domain Rad60-SLD PF11976.8 EIM89832.1 - 0.0011 18.7 0.3 0.0025 17.6 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RanBP PF00641.18 EIM89832.1 - 0.0023 17.2 2.4 0.0023 17.2 2.4 3.6 4 0 0 4 4 4 1 Zn-finger in Ran binding protein and others Gaa1 PF04114.14 EIM89833.1 - 1.3e-107 360.9 1.0 1.7e-107 360.5 1.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Ycf9 PF01737.17 EIM89833.1 - 1.8 8.5 11.7 1.6 8.6 0.3 4.6 5 0 0 5 5 5 0 YCF9 DUF4698 PF15769.5 EIM89834.1 - 8.7 5.3 7.4 14 4.6 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) LUC7 PF03194.15 EIM89835.1 - 2.3e-69 233.9 3.6 2.8e-69 233.6 3.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Ada3 PF10198.9 EIM89835.1 - 0.027 14.6 1.8 0.078 13.1 1.7 1.8 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Ank_4 PF13637.6 EIM89836.1 - 4.3e-12 46.3 0.1 1.9e-08 34.7 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM89836.1 - 8.6e-10 39.1 0.0 4.7e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM89836.1 - 4.9e-08 33.1 0.0 0.0097 16.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM89836.1 - 2.5e-07 30.5 0.0 0.089 13.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EIM89836.1 - 0.0057 17.0 0.0 2.4 8.8 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat NPR3 PF03666.13 EIM89836.1 - 0.061 12.1 6.2 0.092 11.5 6.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF3_subunit PF08597.10 EIM89836.1 - 1.6 8.6 24.2 2.9 7.7 24.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 EIM89836.1 - 3.2 6.4 10.0 4.9 5.8 10.0 1.2 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 EIM89836.1 - 4.2 6.7 9.8 32 3.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 EIM89836.1 - 5.1 6.8 14.1 9.2 6.0 14.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CTNNBL PF08216.11 EIM89838.1 - 0.025 14.8 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear FRG1 PF06229.12 EIM89839.1 - 1.1e-25 90.4 0.2 1.1e-25 90.4 0.2 1.5 2 0 0 2 2 2 1 FRG1-like domain DUF1754 PF08555.10 EIM89839.1 - 0.005 17.6 10.0 0.57 11.0 3.1 2.3 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Fascin PF06268.13 EIM89839.1 - 0.018 15.3 0.0 0.046 13.9 0.0 1.7 1 1 0 1 1 1 0 Fascin domain Ribosomal_L26 PF16906.5 EIM89840.1 - 1.7e-36 124.5 4.5 3e-36 123.7 4.5 1.4 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EIM89840.1 - 5.9e-09 35.6 4.5 5.9e-09 35.6 4.5 2.0 2 1 0 2 2 2 1 KOW motif DUF1442 PF07279.11 EIM89840.1 - 0.049 12.9 0.8 0.069 12.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) ATP-synt_D PF01813.17 EIM89841.1 - 1.6e-69 233.7 1.6 2.5e-69 233.1 1.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Lactonase PF10282.9 EIM89842.1 - 9.6e-10 38.2 0.7 2.9e-06 26.8 0.0 3.3 1 1 2 3 3 3 2 Lactonase, 7-bladed beta-propeller RnfC_N PF13375.6 EIM89842.1 - 0.0032 17.4 0.1 0.0097 15.8 0.1 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain LAT PF15234.6 EIM89842.1 - 0.07 12.8 2.5 0.16 11.7 2.5 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Cpn60_TCP1 PF00118.24 EIM89843.1 - 2.2e-147 491.7 11.0 2.5e-147 491.5 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UFD1 PF03152.14 EIM89844.1 - 4e-70 234.8 0.0 5.1e-70 234.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3237 PF11578.8 EIM89844.1 - 0.069 13.0 0.3 0.22 11.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) WLM PF08325.10 EIM89844.1 - 2.7 8.0 6.9 13 5.8 1.2 2.2 2 0 0 2 2 2 0 WLM domain NMT_C PF02799.15 EIM89845.1 - 1.1e-83 279.9 0.1 1.9e-83 279.1 0.1 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EIM89845.1 - 3.3e-78 261.1 0.0 5.3e-78 260.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EIM89845.1 - 2.9e-05 24.1 0.0 0.00026 21.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM89845.1 - 0.002 18.4 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM89845.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S25 PF03297.15 EIM89845.1 - 0.3 11.3 3.2 36 4.6 2.8 2.6 2 0 0 2 2 2 0 S25 ribosomal protein OGG_N PF07934.12 EIM89846.1 - 7.4e-33 113.2 0.0 1.2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EIM89846.1 - 7.5e-15 55.3 0.0 1.4e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EIM89846.1 - 0.00062 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif NPR2 PF06218.11 EIM89847.1 - 9.5e-108 360.8 0.5 4e-85 286.2 3.9 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Pro-NT_NN PF07421.11 EIM89847.1 - 0.062 13.6 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor NPR3 PF03666.13 EIM89847.1 - 0.38 9.5 1.2 1.2 7.8 0.0 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RTC PF01137.21 EIM89848.1 - 4.7e-57 192.7 0.0 5.4e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EIM89848.1 - 3.7e-38 130.2 0.0 6e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PilZ PF07238.14 EIM89848.1 - 0.088 13.1 0.0 9.1 6.7 0.0 2.4 2 0 0 2 2 2 0 PilZ domain ThiF PF00899.21 EIM89849.1 - 1.5e-62 211.1 0.0 2.1e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EIM89849.1 - 1.3e-24 86.2 0.2 2e-24 85.5 0.2 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EIM89849.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EIM89849.1 - 0.032 13.8 1.0 0.08 12.5 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EIM89849.1 - 0.047 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 EIM89849.1 - 0.12 13.0 0.1 0.34 11.6 0.1 1.8 1 0 0 1 1 1 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 EIM89849.1 - 0.17 11.8 0.1 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site NmrA PF05368.13 EIM89850.1 - 7e-11 42.1 0.0 2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM89850.1 - 4.2e-05 23.5 0.0 0.00013 21.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM89850.1 - 4.4e-05 23.8 0.0 6.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EIM89850.1 - 0.00049 20.4 0.0 0.00077 19.7 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.16 EIM89850.1 - 0.039 14.6 0.0 0.065 13.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EIM89850.1 - 0.059 13.5 0.1 1.1 9.4 0.1 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ecm33 PF12454.8 EIM89850.1 - 0.11 12.6 0.5 0.73 10.0 0.1 2.2 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Epimerase PF01370.21 EIM89850.1 - 0.16 11.4 0.0 0.41 10.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Torus PF16131.5 EIM89851.1 - 5.7e-07 30.2 0.1 1.2e-06 29.2 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 EIM89851.1 - 3.4e-06 26.9 2.9 1.1e-05 25.2 2.9 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 EIM89851.1 - 0.0015 18.7 0.4 0.0073 16.5 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 EIM89851.1 - 0.013 15.3 3.3 0.034 13.9 3.3 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 EIM89851.1 - 0.019 14.8 3.5 0.052 13.5 3.5 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EIM89851.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 EIM89851.1 - 0.063 13.8 3.2 0.16 12.5 3.2 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Sulf_transp PF04143.14 EIM89852.1 - 4.7e-13 49.4 19.8 1.2e-10 41.5 11.9 2.5 2 0 0 2 2 2 2 Sulphur transport adh_short PF00106.25 EIM89853.1 - 9.3e-25 87.2 0.0 7.3e-22 77.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89853.1 - 1.4e-15 57.5 0.0 2.9e-15 56.5 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89853.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 EIM89854.1 - 2.4e-15 56.5 0.0 1.3e-09 37.8 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89854.1 - 3.1e-07 30.2 0.0 3.5e-06 26.8 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89854.1 - 0.042 13.8 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 EIM89854.1 - 0.15 11.4 0.0 0.44 10.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF726 PF05277.12 EIM89855.1 - 1.9e-90 303.3 2.0 2.3e-90 303.0 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 EIM89855.1 - 0.0042 17.1 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Cutinase WSK PF03832.13 EIM89855.1 - 0.11 12.2 0.6 0.29 10.8 0.6 1.7 1 0 0 1 1 1 0 WSK motif Y_phosphatase3 PF13350.6 EIM89856.1 - 4.3e-59 200.3 0.0 5.1e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EIM89856.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EIM89856.1 - 0.0016 18.1 0.0 0.0022 17.6 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EIM89856.1 - 0.12 12.2 0.0 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EIM89856.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate LEA_2 PF03168.13 EIM89857.1 - 4.9e-07 30.2 0.0 9.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 EIM89857.1 - 0.0023 17.2 0.5 0.0029 16.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Vac7 PF12751.7 EIM89857.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 JmjC PF02373.22 EIM89858.1 - 1.2e-13 51.5 0.0 2.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pkinase PF00069.25 EIM89859.1 - 2.1e-23 83.0 0.0 2.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89859.1 - 4.9e-10 39.1 0.0 6.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM89859.1 - 4.1e-08 32.4 0.0 5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM89859.1 - 0.02 14.9 0.0 2.8 7.8 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Vac_ImportDeg PF09783.9 EIM89860.1 - 4.9e-41 140.2 0.0 3.4e-40 137.5 0.0 2.1 1 1 0 1 1 1 1 Vacuolar import and degradation protein MFS_1 PF07690.16 EIM89861.1 - 7.7e-55 186.2 42.1 7.7e-55 186.2 42.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM89861.1 - 2e-18 66.1 17.0 3e-18 65.6 17.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIM89861.1 - 1.5e-13 50.5 11.9 1.5e-13 50.5 11.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EIM89861.1 - 7.4e-07 28.1 23.7 1.9e-06 26.7 1.5 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein DUF3611 PF12263.8 EIM89861.1 - 0.0066 16.4 1.6 0.017 15.0 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3611) DUF3624 PF12292.8 EIM89861.1 - 0.082 13.3 0.2 0.47 10.9 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Ras PF00071.22 EIM89862.1 - 3.5e-50 169.8 0.0 4.1e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM89862.1 - 4.5e-30 104.3 0.1 7.8e-30 103.6 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM89862.1 - 3.6e-10 39.6 0.0 4.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIM89862.1 - 0.00031 20.2 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIM89862.1 - 0.0021 18.1 0.0 0.0038 17.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EIM89862.1 - 0.006 17.0 0.1 0.049 14.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 EIM89862.1 - 0.009 15.2 1.4 1 8.5 0.2 2.5 2 1 0 2 2 2 1 G-protein alpha subunit Pox_A32 PF04665.12 EIM89862.1 - 0.022 14.2 0.5 0.036 13.5 0.1 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 EIM89862.1 - 0.024 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EIM89862.1 - 0.049 13.4 0.3 0.072 12.8 0.1 1.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EIM89862.1 - 0.063 13.2 0.1 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 EIM89862.1 - 0.099 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EIM89862.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain STAS PF01740.21 EIM89862.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 STAS domain AAA_33 PF13671.6 EIM89862.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EIM89862.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Septin BCS1_N PF08740.11 EIM89863.1 - 1.3e-45 155.7 0.5 1.9e-45 155.2 0.5 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EIM89863.1 - 7.1e-18 65.3 0.0 1.5e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM89863.1 - 0.00014 22.3 0.8 0.00065 20.1 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EIM89863.1 - 0.0045 16.6 0.0 0.03 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EIM89863.1 - 0.006 16.3 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EIM89863.1 - 0.011 16.3 0.0 0.057 14.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 EIM89863.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EIM89863.1 - 0.02 15.4 0.1 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 EIM89863.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EIM89863.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EIM89863.1 - 0.034 13.5 0.0 0.74 9.1 0.0 2.1 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 EIM89863.1 - 0.039 14.4 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EIM89863.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EIM89863.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIM89863.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EIM89863.1 - 0.11 12.9 0.1 0.32 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EIM89863.1 - 0.12 12.3 0.0 3.6 7.5 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EIM89863.1 - 0.15 12.3 0.0 0.49 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain WBS_methylT PF12589.8 EIM89864.1 - 2.1e-23 82.9 9.8 3.2e-23 82.3 9.8 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EIM89864.1 - 8.6e-09 35.9 0.0 1.6e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM89864.1 - 2e-07 31.6 0.0 4.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM89864.1 - 0.00012 22.8 0.0 0.00036 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM89864.1 - 0.00076 19.4 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM89864.1 - 0.0019 18.0 0.0 0.0054 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EIM89864.1 - 0.029 14.7 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PUMA PF15826.5 EIM89864.1 - 0.031 14.5 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis TRAPP PF04051.16 EIM89865.1 - 3.2e-35 121.0 0.0 4.3e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component XAP5 PF04921.14 EIM89866.1 - 7.5e-88 294.5 5.3 7.5e-88 294.5 5.3 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF2333 PF10095.9 EIM89866.1 - 1 8.3 4.5 1.6 7.7 4.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) adh_short PF00106.25 EIM89867.1 - 1.3e-27 96.6 0.0 4.1e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89867.1 - 9.4e-17 61.3 0.1 2.1e-16 60.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89867.1 - 0.0031 17.4 0.1 0.0051 16.7 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EIM89867.1 - 0.015 14.4 0.0 0.032 13.4 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 EIM89869.1 - 2.9e-28 98.7 0.0 2.3e-23 82.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89869.1 - 1.1e-15 57.9 0.0 2.9e-15 56.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89869.1 - 0.0053 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EIM89869.1 - 0.11 11.5 0.0 0.26 10.4 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Pyr_redox_3 PF13738.6 EIM89869.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 EIM89870.1 - 1.4e-26 93.2 0.0 3.1e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89870.1 - 6.8e-16 58.5 0.1 2.6e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89870.1 - 0.0028 17.6 0.1 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EIM89871.1 - 4.8e-28 98.0 0.0 7.9e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89871.1 - 2.8e-16 59.8 0.0 1.9e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89871.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EIM89871.1 - 0.0091 15.1 0.1 0.024 13.7 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EIM89872.1 - 1.1e-14 54.5 0.0 2.4e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM89872.1 - 2.3e-08 33.8 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM89872.1 - 3.8e-08 32.7 0.0 5.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM89872.1 - 2.3e-07 30.9 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM89872.1 - 0.00012 21.7 0.1 0.00019 21.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EIM89872.1 - 0.00052 19.3 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 EIM89872.1 - 0.024 14.1 0.0 0.095 12.1 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Mito_carr PF00153.27 EIM89873.1 - 2.8e-43 145.8 1.5 2.9e-14 52.8 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF5537 PF17690.1 EIM89873.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5537) Rrn6 PF10214.9 EIM89874.1 - 3.8e-17 62.1 10.8 3.7e-06 25.8 3.2 3.2 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.22 EIM89875.1 - 3.8e-22 78.8 1.2 6.2e-20 71.5 0.5 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 CLASP_N PF12348.8 EIM89876.1 - 8.5e-21 74.6 0.0 1.8e-09 37.5 0.0 5.0 4 0 0 4 4 4 4 CLASP N terminal HEAT_2 PF13646.6 EIM89876.1 - 9.9e-11 41.9 12.6 0.0091 16.4 0.0 9.0 7 3 2 9 9 9 2 HEAT repeats Cnd1 PF12717.7 EIM89876.1 - 4.1e-08 33.4 0.0 0.19 11.8 0.0 7.0 7 2 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIM89876.1 - 6e-08 32.3 22.6 0.0085 16.3 0.0 10.9 13 0 0 13 13 13 2 HEAT repeat HEAT_EZ PF13513.6 EIM89876.1 - 0.00045 20.7 4.4 0.17 12.5 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.23 EIM89876.1 - 0.0051 16.8 0.2 1.4 9.1 0.0 4.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat TAN PF11640.8 EIM89876.1 - 0.035 14.2 5.1 0.38 10.9 0.2 4.0 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Vac14_Fab1_bd PF12755.7 EIM89876.1 - 0.11 13.0 0.0 60 4.3 0.0 5.0 6 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 EIM89876.1 - 0.18 11.4 0.4 1.6e+02 1.8 0.1 4.3 4 0 0 4 4 4 0 NUC173 domain MMS19_N PF14500.6 EIM89876.1 - 0.57 9.7 8.1 18 4.8 0.0 5.5 7 0 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II FAD_binding_3 PF01494.19 EIM89877.1 - 1.5e-49 169.1 0.0 9.9e-49 166.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM89877.1 - 3.3e-09 36.4 0.2 5.9e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM89877.1 - 3.1e-07 29.9 0.4 5e-07 29.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EIM89877.1 - 8e-07 28.4 0.7 8.3e-06 25.1 0.2 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EIM89877.1 - 1e-05 24.9 0.4 3.8e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM89877.1 - 3.1e-05 23.5 0.0 6.9e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM89877.1 - 9.1e-05 21.8 0.1 0.00016 21.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EIM89877.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM89877.1 - 0.0002 20.2 0.9 0.0014 17.4 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EIM89877.1 - 0.00029 21.0 0.1 0.00085 19.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EIM89877.1 - 0.00041 20.9 0.5 0.38 11.3 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EIM89877.1 - 0.0008 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.6 EIM89877.1 - 0.0024 17.9 0.3 0.1 12.6 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EIM89877.1 - 0.0038 17.3 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EIM89877.1 - 0.0041 16.3 1.2 0.0056 15.8 0.4 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.18 EIM89877.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain SE PF08491.10 EIM89877.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 EIM89877.1 - 0.023 13.5 0.5 0.2 10.5 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EIM89877.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ANAPC5 PF12862.7 EIM89878.1 - 3.9e-10 39.7 1.8 4.7e-09 36.2 0.9 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EIM89878.1 - 0.00039 20.6 5.6 0.27 11.6 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat HCV_NS5a PF01506.19 EIM89878.1 - 0.012 15.4 0.5 0.028 14.3 0.5 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor SIN1 PF05422.12 EIM89878.1 - 0.11 13.1 0.1 0.2 12.2 0.1 1.3 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) TPR_2 PF07719.17 EIM89878.1 - 0.15 12.2 9.9 0.52 10.6 1.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIM89878.1 - 0.36 11.5 2.3 3.6 8.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIM89878.1 - 0.59 10.1 8.8 0.32 10.9 0.9 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RRN7 PF11781.8 EIM89878.1 - 3.3 7.5 6.0 6.9 6.5 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 NOC3p PF07540.11 EIM89879.1 - 1.1e-31 109.2 0.3 3.2e-31 107.6 0.0 2.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EIM89879.1 - 1.9e-19 70.3 0.0 1.9e-19 70.3 0.0 3.1 3 1 1 4 4 4 1 CBF/Mak21 family DUF4337 PF14235.6 EIM89879.1 - 0.022 14.9 5.1 0.06 13.5 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TEA PF01285.18 EIM89880.1 - 4.5e-15 55.5 0.9 8.7e-15 54.6 0.9 1.5 1 0 0 1 1 1 1 TEA/ATTS domain UEV PF05743.13 EIM89881.1 - 1.8e-31 108.5 0.0 1.8e-31 108.5 0.0 2.2 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 EIM89881.1 - 4e-29 100.4 0.4 6.3e-29 99.7 0.4 1.3 1 0 0 1 1 1 1 Vps23 core domain EspB PF05802.11 EIM89881.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein MSC PF09402.10 EIM89882.1 - 2.4e-93 313.3 0.0 3.3e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EIM89882.1 - 2.7e-10 39.8 0.0 6.5e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain ox_reductase_C PF08635.10 EIM89883.1 - 3.9e-72 240.5 0.3 5.6e-72 240.0 0.3 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EIM89883.1 - 1.4e-22 80.7 0.0 2.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EIM89883.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain UPF0242 PF06785.11 EIM89884.1 - 0.0015 18.7 0.5 0.0017 18.5 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus MRPL52 PF18699.1 EIM89884.1 - 0.0022 18.1 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 Mitoribosomal protein mL52 APG6_N PF17675.1 EIM89884.1 - 0.0035 17.9 1.1 0.0038 17.8 1.1 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Rx_N PF18052.1 EIM89884.1 - 0.012 15.9 3.2 0.016 15.5 3.2 1.2 1 0 0 1 1 1 0 Rx N-terminal domain ATG16 PF08614.11 EIM89884.1 - 0.013 15.8 7.4 0.013 15.8 7.4 1.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EIM89884.1 - 0.2 12.3 3.5 0.35 11.5 3.5 1.4 1 0 0 1 1 1 0 SlyX ZapB PF06005.12 EIM89884.1 - 3.2 8.3 12.0 5 7.6 12.0 1.2 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EIM89884.1 - 7.1 6.5 9.0 10 6.0 9.0 1.2 1 0 0 1 1 1 0 Septum formation initiator PIG-Y PF15159.6 EIM89886.1 - 2.9e-17 63.4 6.3 3.3e-17 63.2 6.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PSI_PsaF PF02507.15 EIM89886.1 - 0.27 11.1 1.9 0.26 11.1 0.3 1.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III Sfi1 PF08457.10 EIM89888.1 - 1.4e-31 109.7 114.7 8.7e-19 67.5 56.7 4.8 1 1 4 5 5 5 5 Sfi1 spindle body protein DUF1948 PF09185.10 EIM89888.1 - 0.077 12.9 6.1 0.03 14.2 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1948) CLTH PF10607.9 EIM89889.1 - 1.9e-18 66.7 0.0 3.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EIM89889.1 - 8.5e-06 25.7 0.3 1.9e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EIM89889.1 - 0.0012 18.3 3.3 0.0013 18.2 0.1 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger Mod_r PF07200.13 EIM89889.1 - 0.012 15.7 0.6 0.02 15.0 0.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DLP_helical PF18709.1 EIM89889.1 - 0.013 14.7 0.7 0.019 14.2 0.7 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain HMG_box PF00505.19 EIM89889.1 - 0.024 15.1 0.3 0.058 13.8 0.3 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box zf-C3HC4 PF00097.25 EIM89889.1 - 0.057 13.3 0.8 0.11 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM89889.1 - 0.058 13.2 1.0 0.13 12.1 1.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM89889.1 - 0.079 12.9 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Pellino PF04710.14 EIM89889.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Pellino zf-Nse PF11789.8 EIM89889.1 - 0.12 12.2 1.3 0.27 11.1 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 EIM89889.1 - 0.14 12.5 0.5 0.27 11.6 0.5 1.5 1 0 0 1 1 1 0 Ring finger domain HMG_box_2 PF09011.10 EIM89889.1 - 0.16 12.5 0.3 0.43 11.2 0.2 1.7 2 0 0 2 2 1 0 HMG-box domain zf-C3HC4_4 PF15227.6 EIM89889.1 - 0.41 10.8 2.3 0.34 11.1 0.7 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Pirin PF02678.16 EIM89891.1 - 6.1e-30 103.4 0.1 1.1e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EIM89891.1 - 1.1e-24 86.7 0.0 3.1e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EIM89891.1 - 0.04 13.6 1.2 0.078 12.7 0.6 1.8 2 0 0 2 2 2 0 Cupin domain AA_permease PF00324.21 EIM89892.1 - 2.5e-127 425.4 36.5 3e-127 425.1 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM89892.1 - 2e-27 96.1 40.5 4e-27 95.1 40.5 1.5 1 1 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 EIM89892.1 - 0.16 11.7 0.1 12 5.6 0.0 2.8 2 0 0 2 2 2 0 Non-classical export protein 1 ECH_1 PF00378.20 EIM89893.1 - 5.6e-24 84.8 0.0 7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIM89893.1 - 1.5e-12 47.7 0.0 1.8e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Mub_B2 PF17966.1 EIM89893.1 - 0.035 14.8 0.2 0.067 13.9 0.2 1.4 1 0 0 1 1 1 0 Mub B2-like domain HEAT_2 PF13646.6 EIM89894.1 - 0.016 15.5 0.2 0.46 10.9 0.1 3.1 2 0 0 2 2 2 0 HEAT repeats Arm PF00514.23 EIM89894.1 - 0.14 12.2 0.8 10 6.3 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 EIM89894.1 - 0.17 10.4 0.0 0.37 9.2 0.0 1.5 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 EIM89895.1 - 4.1e-121 405.1 5.5 5.4e-121 404.7 5.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EIM89895.1 - 1.5e-57 194.1 1.9 1.6e-54 184.3 0.3 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIM89895.1 - 1.1e-12 48.2 7.4 6.2e-06 26.5 0.3 5.3 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.22 EIM89895.1 - 7.5e-09 35.1 4.5 0.065 13.5 0.0 6.4 8 1 0 8 8 8 3 HEAT repeat RTP1_C1 PF10363.9 EIM89895.1 - 0.0017 18.6 2.3 4.3 7.6 0.0 4.1 2 1 2 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EIM89895.1 - 0.011 15.7 1.0 15 5.8 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EIM89895.1 - 0.14 11.7 0.0 2.4 7.6 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal DUF4477 PF14780.6 EIM89896.1 - 3.7e-07 30.0 0.1 4.6e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) TDA11 PF17084.5 EIM89896.1 - 0.079 11.9 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 Cu_bind_like PF02298.17 EIM89897.1 - 1.3e-05 25.1 0.4 3.4e-05 23.8 0.4 1.7 1 0 0 1 1 1 1 Plastocyanin-like domain Pyr_redox_2 PF07992.14 EIM89899.1 - 6.6e-11 42.0 0.0 6.4e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM89899.1 - 0.00092 18.9 0.1 0.036 13.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM89899.1 - 0.0036 17.3 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EIM89899.1 - 0.0084 15.4 0.0 0.42 9.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Malic_M PF03949.15 EIM89899.1 - 0.015 14.6 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain FAD_binding_2 PF00890.24 EIM89899.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EIM89899.1 - 0.046 12.4 0.1 0.16 10.7 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EIM89899.1 - 0.07 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EIM89899.1 - 0.082 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EIM89899.1 - 0.084 11.7 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 EIM89899.1 - 0.11 11.6 0.0 0.36 9.9 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM89899.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-C2HE PF16278.5 EIM89900.1 - 8.3e-14 51.8 1.2 2.1e-13 50.5 1.2 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EIM89900.1 - 2e-13 50.8 0.5 4.1e-13 49.8 0.1 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EIM89900.1 - 4.4e-10 40.2 0.0 1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 HIT domain DUF2630 PF10944.8 EIM89900.1 - 0.0045 17.4 0.5 0.0045 17.4 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2630) Dynein_light PF01221.18 EIM89900.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Dynein light chain type 1 NAD_binding_1 PF00175.21 EIM89900.1 - 0.22 12.2 1.7 21 5.8 0.1 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain zf-C2H2_2 PF12756.7 EIM89900.1 - 0.35 11.2 2.2 1.1 9.7 2.1 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) BTB PF00651.31 EIM89901.1 - 0.00042 20.5 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RabGAP-TBC PF00566.18 EIM89902.1 - 1.3e-41 142.7 4.4 5.9e-39 134.0 4.4 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Lung_7-TM_R PF06814.13 EIM89902.1 - 0.09 12.0 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor PsbN PF02468.15 EIM89903.1 - 4.9 7.1 5.7 1.3 8.9 1.2 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF1264 PF06884.11 EIM89904.1 - 1.5e-71 239.5 0.3 1.8e-71 239.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) NAC PF01849.18 EIM89905.1 - 1.9e-21 75.8 0.0 4.3e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 EIM89905.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Methyltransf_25 PF13649.6 EIM89906.1 - 0.00078 20.1 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM89906.1 - 0.0013 19.3 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM89906.1 - 0.0035 17.1 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM89906.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_28_C PF04101.16 EIM89907.1 - 2.3e-26 92.8 0.0 2.6e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain P5CR_dimer PF14748.6 EIM89908.1 - 6.4e-39 132.4 2.1 1.1e-38 131.6 2.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EIM89908.1 - 5.6e-12 46.1 0.0 1.6e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.29 EIM89911.1 - 1.5e-44 151.6 0.0 5.7e-44 149.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EIM89911.1 - 9.6e-09 35.1 0.1 7e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EIM89911.1 - 1.7e-08 34.6 0.1 4.9e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EIM89911.1 - 7.7e-08 32.6 0.1 3.1e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EIM89911.1 - 8e-08 32.8 3.0 2.9e-05 24.5 0.0 3.3 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EIM89911.1 - 3.2e-06 26.5 0.0 7.7e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EIM89911.1 - 0.00014 22.4 0.1 0.0018 18.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 EIM89911.1 - 0.00023 21.2 0.0 0.0017 18.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EIM89911.1 - 0.00028 21.2 3.2 0.013 15.8 0.1 2.9 2 1 1 3 3 2 1 AAA domain AAA_28 PF13521.6 EIM89911.1 - 0.0003 21.1 0.6 0.0011 19.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 EIM89911.1 - 0.00054 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EIM89911.1 - 0.00074 19.5 0.0 0.0098 15.9 0.1 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EIM89911.1 - 0.001 19.0 0.3 0.0093 15.9 0.0 2.6 4 0 0 4 4 2 1 NTPase RNA_helicase PF00910.22 EIM89911.1 - 0.0012 19.2 0.0 0.006 17.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 EIM89911.1 - 0.0024 17.2 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 EIM89911.1 - 0.003 17.3 0.3 0.0084 15.8 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EIM89911.1 - 0.0032 17.0 0.1 0.021 14.3 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_3 PF17862.1 EIM89911.1 - 0.004 16.9 0.0 0.0099 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EIM89911.1 - 0.0046 16.7 0.2 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EIM89911.1 - 0.0065 16.6 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EIM89911.1 - 0.0084 16.0 0.1 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 EIM89911.1 - 0.0085 15.5 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EIM89911.1 - 0.0091 15.9 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EIM89911.1 - 0.011 15.1 0.4 0.59 9.5 0.0 2.5 3 0 0 3 3 2 0 Bacterial TniB protein AAA_25 PF13481.6 EIM89911.1 - 0.021 14.4 1.8 0.048 13.2 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 EIM89911.1 - 0.025 14.3 0.1 0.057 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EIM89911.1 - 0.042 14.2 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EIM89911.1 - 0.046 13.5 0.4 0.094 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EIM89911.1 - 0.05 14.1 0.1 0.84 10.1 0.0 2.5 3 0 0 3 3 2 0 ABC transporter AFG1_ATPase PF03969.16 EIM89911.1 - 0.061 12.2 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 EIM89911.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 EIM89911.1 - 0.075 12.9 0.9 0.65 9.9 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 EIM89911.1 - 0.1 12.3 0.1 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 EIM89911.1 - 0.11 11.9 0.6 0.48 9.7 0.0 2.2 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 EIM89911.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.19 EIM89911.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.22 EIM89912.1 - 1.5e-10 40.7 0.0 3.8e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Retrotran_gag_2 PF14223.6 EIM89913.1 - 6.7e-08 32.3 0.0 9.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Med3 PF11593.8 EIM89913.1 - 5.1 6.2 8.7 6.9 5.7 8.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Swm2 PF17083.5 EIM89914.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Nucleolar protein Swm2 zf-CCHC_5 PF14787.6 EIM89914.1 - 0.057 13.1 0.1 0.057 13.1 0.1 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Chitin_synth_1 PF01644.17 EIM89916.1 - 1.5e-67 226.6 0.1 2.5e-67 225.9 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIM89916.1 - 1.4e-29 101.8 0.1 2.9e-29 100.8 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIM89916.1 - 2.4e-25 89.2 0.1 4.3e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIM89916.1 - 3.9e-08 33.5 0.1 3.9e-08 33.5 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Abhydrolase_3 PF07859.13 EIM89917.1 - 2.1e-12 47.3 0.0 3.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIM89917.1 - 2e-08 34.0 0.0 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 EIM89917.1 - 8.6e-07 27.9 0.0 6.7e-06 25.0 0.0 1.9 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EIM89917.1 - 0.00062 19.1 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EIM89917.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 EIM89917.1 - 0.0044 16.0 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 EIM89917.1 - 0.021 13.7 0.0 0.57 9.0 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family SNRNP27 PF08648.12 EIM89918.1 - 2.9e-20 72.1 2.2 5e-20 71.3 2.2 1.3 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins SUI1 PF01253.22 EIM89919.1 - 5.3e-28 97.4 0.2 7e-28 97.0 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 PPP4R2 PF09184.11 EIM89920.1 - 4.7e-21 75.6 0.0 4.7e-21 75.6 0.0 2.3 2 1 0 2 2 2 1 PPP4R2 PAP2 PF01569.21 EIM89921.1 - 2.7e-31 108.2 1.4 2.7e-31 108.2 1.4 1.9 1 1 1 2 2 2 1 PAP2 superfamily EptA_B_N PF08019.12 EIM89921.1 - 0.0028 17.6 0.2 0.05 13.5 0.1 2.2 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB DUF5510 PF17629.2 EIM89921.1 - 0.089 12.7 0.4 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Ribosomal_S21e PF01249.18 EIM89922.1 - 6.4e-36 122.3 0.1 7.1e-36 122.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NTF2 PF02136.20 EIM89922.1 - 0.034 14.7 0.0 0.039 14.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain TRAF_BIRC3_bd PF16673.5 EIM89923.1 - 0.032 14.0 1.1 1.4 8.7 1.0 3.1 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Filament PF00038.21 EIM89923.1 - 0.053 13.1 39.1 0.018 14.7 33.7 2.5 1 1 1 2 2 2 0 Intermediate filament protein MAD PF05557.13 EIM89923.1 - 0.86 7.9 43.1 0.54 8.6 31.2 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein NPV_P10 PF05531.12 EIM89923.1 - 1.6 9.2 8.8 0.22 12.0 0.9 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HSP90 PF00183.18 EIM89924.1 - 1e-226 753.8 28.9 1.2e-226 753.6 28.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EIM89924.1 - 8.7e-15 55.2 0.0 1.9e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EIM89924.1 - 9.6e-10 38.4 0.1 3e-09 36.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 EIM89924.1 - 0.025 14.6 1.3 0.033 14.2 0.0 1.8 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_C37 PF05416.12 EIM89924.1 - 2.1 6.8 9.6 1.7 7.1 0.3 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase DUF2052 PF09747.9 EIM89924.1 - 3.6 7.7 14.6 1.7 8.7 9.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Aminotran_5 PF00266.19 EIM89926.1 - 1e-30 107.0 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF4440 PF14534.6 EIM89927.1 - 3.1e-06 27.5 0.0 4.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EIM89927.1 - 6.6e-06 26.7 0.0 8.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EIM89927.1 - 0.0076 16.4 0.1 0.009 16.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain Mtr2 PF10429.9 EIM89927.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 NmrA PF05368.13 EIM89928.1 - 9.5e-26 90.8 0.0 1.2e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM89928.1 - 9.5e-14 51.7 0.0 1.5e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM89928.1 - 2.9e-07 30.8 0.4 4.4e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EIM89928.1 - 2.4e-06 27.6 0.0 5.7e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EIM89928.1 - 0.00012 21.7 0.0 0.014 14.8 0.1 2.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 EIM89928.1 - 0.00044 19.8 0.0 0.00072 19.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 3Beta_HSD PF01073.19 EIM89928.1 - 0.0047 16.0 0.1 0.0068 15.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EIM89928.1 - 0.0063 16.8 0.1 0.0093 16.2 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.15 EIM89928.1 - 0.028 13.4 0.1 0.042 12.8 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_3 PF03447.16 EIM89928.1 - 0.041 14.5 0.1 0.085 13.5 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EIM89928.1 - 0.064 12.6 0.1 0.099 12.0 0.1 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.21 EIM89929.1 - 4.5e-73 246.0 0.0 5.1e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 EIM89930.1 - 1.2e-24 86.3 0.2 2.1e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM89930.1 - 2.3e-18 66.4 0.2 3.8e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM89930.1 - 1e-05 25.1 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIM89930.1 - 0.003 18.6 0.0 0.0055 17.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EIM89930.1 - 0.0035 17.3 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding ELFV_dehydrog PF00208.21 EIM89930.1 - 0.0068 16.2 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TPP_enzyme_C PF02775.21 EIM89930.1 - 0.098 12.4 0.3 2.2 8.0 0.1 2.6 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Dynamin_M PF01031.20 EIM89931.1 - 1.8e-103 345.7 0.0 4.6e-103 344.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EIM89931.1 - 1.2e-55 188.1 0.0 2.8e-55 186.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EIM89931.1 - 1.3e-28 98.9 1.8 1.3e-28 98.9 1.8 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EIM89931.1 - 0.0012 18.9 0.0 0.0042 17.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTF2 PF02136.20 EIM89932.1 - 5.8e-32 110.8 0.0 6.5e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SLT_L PF14718.6 EIM89933.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain FAD_binding_3 PF01494.19 EIM89934.1 - 3e-77 260.2 0.0 3.7e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM89934.1 - 1.8e-08 34.6 0.1 3.1e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EIM89934.1 - 2.5e-06 27.3 1.2 8.6e-05 22.3 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM89934.1 - 2.3e-05 24.5 0.1 7.1e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM89934.1 - 0.00063 19.0 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EIM89934.1 - 0.0036 16.6 0.0 0.009 15.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM89934.1 - 0.005 15.9 0.1 0.0085 15.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EIM89934.1 - 0.0051 15.6 0.0 0.0073 15.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM89934.1 - 0.0061 15.9 0.1 0.0094 15.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EIM89934.1 - 0.0095 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EIM89934.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EIM89934.1 - 0.019 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EIM89934.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EIM89934.1 - 0.021 15.4 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM89934.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EIM89934.1 - 0.035 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_1N PF02870.15 EIM89934.1 - 0.041 14.7 0.0 0.097 13.5 0.0 1.6 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Glu_dehyd_C PF16912.5 EIM89934.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DEAD PF00270.29 EIM89935.1 - 2e-48 164.5 0.0 3.2e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM89935.1 - 6.9e-31 106.9 0.0 2.5e-30 105.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM89935.1 - 2.6e-06 27.6 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EIM89935.1 - 0.0022 17.2 0.1 0.0062 15.8 0.0 1.7 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 EIM89935.1 - 0.0057 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain HTH_WhiA PF02650.14 EIM89935.1 - 0.11 12.8 0.4 0.53 10.7 0.0 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain TRAPPC10 PF12584.8 EIM89936.1 - 1.9e-36 125.2 0.0 3.4e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 BNR_2 PF13088.6 EIM89937.1 - 2.1e-16 60.1 0.2 2.1e-08 33.8 0.5 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EIM89937.1 - 1.2e-07 30.7 17.8 0.15 12.1 1.1 5.3 4 0 0 4 4 4 4 BNR/Asp-box repeat BNR_3 PF13859.6 EIM89937.1 - 2.3e-06 27.1 1.9 3.4e-06 26.6 1.9 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR_4 PF15892.5 EIM89937.1 - 0.00073 19.0 1.4 0.015 14.7 0.6 2.5 1 1 0 2 2 2 1 BNR repeat-containing family member CyRPA PF18638.1 EIM89937.1 - 0.011 15.0 0.2 3.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Cysteine-Rich Protective Antigen 6 bladed domain Staphostatin_B PF09023.10 EIM89937.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Staphostatin B TraK PF06586.11 EIM89937.1 - 0.22 11.2 2.7 9.9 5.8 0.1 3.1 2 2 1 3 3 3 0 TraK protein F5_F8_type_C PF00754.25 EIM89937.1 - 1.3 9.1 15.7 3.6 7.7 0.5 4.1 1 1 3 4 4 4 0 F5/8 type C domain ALG3 PF05208.13 EIM89938.1 - 4e-139 464.0 3.0 4.7e-139 463.8 3.0 1.0 1 0 0 1 1 1 1 ALG3 protein Planc_extracel PF07595.12 EIM89940.1 - 0.13 12.1 3.7 3.8 7.5 1.4 2.9 2 0 0 2 2 2 0 Planctomycete extracellular Ist1 PF03398.14 EIM89941.1 - 4.7e-33 114.4 0.0 7.2e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 EIM89941.1 - 2.2e-14 53.7 0.1 5.4e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PIN_9 PF18477.1 EIM89941.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 PIN like domain PIG-H PF10181.9 EIM89942.1 - 1.2e-15 57.1 0.0 1.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Cellulase PF00150.18 EIM89943.1 - 6.4e-13 48.8 0.1 2.3e-12 46.9 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CDH-cyt PF16010.5 EIM89944.1 - 1.2e-53 181.5 2.2 2.1e-53 180.7 2.2 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CBM_1 PF00734.18 EIM89944.1 - 3.3e-11 42.9 13.3 3.3e-11 42.9 13.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DOMON PF03351.17 EIM89944.1 - 0.033 14.4 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 DOMON domain Ribosomal_L7Ae PF01248.26 EIM89945.1 - 1.5e-25 88.7 0.1 1.8e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EIM89945.1 - 0.00053 20.1 0.0 0.00071 19.7 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EIM89945.1 - 0.00081 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain UQ_con PF00179.26 EIM89946.1 - 4.9e-49 165.6 0.0 5.5e-49 165.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIM89946.1 - 0.00073 19.2 0.0 0.00087 19.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Proteasome PF00227.26 EIM89947.1 - 1e-48 165.3 0.1 1.3e-48 165.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Syja_N PF02383.18 EIM89948.1 - 5.3e-95 318.4 0.0 7.9e-95 317.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EIM89948.1 - 3.4e-31 107.3 0.0 6.2e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase LIM PF00412.22 EIM89949.1 - 2.9e-13 49.8 27.1 8.7e-11 41.9 5.8 4.5 5 0 0 5 5 5 3 LIM domain CxC6 PF18721.1 EIM89949.1 - 0.056 13.7 8.1 0.2 12.0 8.1 1.9 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases zf_UBZ PF18439.1 EIM89949.1 - 0.32 10.6 0.0 0.32 10.6 0.0 5.1 4 1 1 5 5 5 0 Ubiquitin-Binding Zinc Finger DUF2321 PF10083.9 EIM89949.1 - 0.39 10.4 3.3 0.78 9.4 3.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Fungal_trans PF04082.18 EIM89951.1 - 4.2e-22 78.4 0.8 8.7e-22 77.4 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM89951.1 - 1.5e-10 41.0 3.6 2.8e-10 40.1 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2_BFD PF04324.15 EIM89951.1 - 0.54 10.6 2.6 0.68 10.3 0.5 2.2 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DHHC PF01529.20 EIM89952.1 - 1.8e-35 121.9 12.9 3.4e-35 121.1 12.9 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase BLACT_WH PF17778.1 EIM89953.1 - 4e-17 61.9 0.6 2.4e-16 59.4 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EIM89953.1 - 7.5e-14 52.2 4.6 1.5e-13 51.2 4.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIM89953.1 - 5.1e-06 26.1 1.1 1.2e-05 24.9 1.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_6 PF08030.12 EIM89953.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain F-box-like PF12937.7 EIM89954.1 - 0.00038 20.3 2.4 0.001 18.9 0.0 2.5 2 0 0 2 2 2 1 F-box-like Isochorismatase PF00857.20 EIM89955.1 - 1.4e-21 77.4 0.0 3.1e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Pyr_redox_2 PF07992.14 EIM89956.1 - 1.1e-66 225.1 0.3 1.4e-66 224.7 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EIM89956.1 - 3.7e-34 117.3 0.1 2.3e-33 114.7 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EIM89956.1 - 6.4e-19 68.3 4.6 5e-18 65.4 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM89956.1 - 1.7e-15 57.1 0.0 1.3e-14 54.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM89956.1 - 1.7e-08 33.6 3.7 0.002 16.9 0.0 3.1 3 1 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 EIM89956.1 - 5.4e-08 32.6 0.1 7.7e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EIM89956.1 - 1.4e-07 31.0 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EIM89956.1 - 0.00077 18.7 3.9 0.0099 15.0 2.3 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EIM89956.1 - 0.0028 16.8 3.4 0.0048 16.0 0.9 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM89956.1 - 0.048 13.9 0.8 0.048 13.9 0.8 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM89956.1 - 0.06 12.6 1.5 0.14 11.4 0.8 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EIM89956.1 - 0.076 13.0 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EIM89956.1 - 0.081 12.1 9.3 7.4 5.7 0.0 3.9 3 1 1 4 4 4 0 FAD binding domain AlaDh_PNT_C PF01262.21 EIM89956.1 - 0.11 11.8 0.9 2.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EIM89956.1 - 0.24 11.3 1.3 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MA3 PF02847.17 EIM89957.1 - 2.5e-28 98.3 0.3 6e-28 97.1 0.3 1.7 1 0 0 1 1 1 1 MA3 domain PBP1_TM PF14812.6 EIM89957.1 - 0.085 13.2 0.7 0.23 11.8 0.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Wza_C PF18412.1 EIM89958.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain Sterol-sensing PF12349.8 EIM89959.1 - 3.3e-35 121.2 4.8 3.3e-35 121.2 4.8 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EIM89959.1 - 2e-11 42.8 0.2 3.2e-11 42.1 0.2 1.2 1 0 0 1 1 1 1 Patched family Biotin_lipoyl PF00364.22 EIM89960.1 - 1.1e-19 70.0 0.9 2.4e-19 68.9 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EIM89960.1 - 3.1e-08 33.8 0.1 8.1e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain DUF1631 PF07793.11 EIM89960.1 - 0.021 13.3 3.3 0.026 13.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Biotin_lipoyl_2 PF13533.6 EIM89960.1 - 0.042 13.7 2.2 2 8.3 0.0 3.3 2 1 1 3 3 3 0 Biotin-lipoyl like PI-PLC-X PF00388.19 EIM89961.1 - 0.0037 16.9 0.0 0.0055 16.3 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain NDUF_B7 PF05676.13 EIM89961.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PsaM PF07465.13 EIM89963.1 - 0.055 13.2 1.2 0.2 11.4 0.4 2.1 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Fe-ADH PF00465.19 EIM89964.1 - 3.6e-78 262.9 3.5 4.1e-78 262.7 3.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EIM89964.1 - 2.4e-15 56.9 1.3 3.3e-15 56.5 1.3 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Rad1 PF02144.16 EIM89965.1 - 3.2e-62 210.1 0.0 5.6e-61 206.0 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SnoaL_2 PF12680.7 EIM89966.1 - 1.5e-05 25.6 0.0 2.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EIM89966.1 - 0.0092 16.1 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EIM89966.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) NTF2 PF02136.20 EIM89966.1 - 0.021 15.4 0.0 0.028 15.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SnoaL PF07366.12 EIM89966.1 - 0.047 13.5 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase FAD_binding_3 PF01494.19 EIM89967.1 - 2.4e-77 260.6 0.0 3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM89967.1 - 8.1e-09 35.7 0.1 1.4e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EIM89967.1 - 2.2e-06 27.5 1.0 8.6e-05 22.3 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM89967.1 - 2.4e-05 24.5 0.1 7.1e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM89967.1 - 0.00068 19.0 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EIM89967.1 - 0.0035 16.6 0.0 0.0083 15.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIM89967.1 - 0.005 15.9 0.1 0.0085 15.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EIM89967.1 - 0.0051 15.6 0.0 0.0073 15.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM89967.1 - 0.006 15.9 0.1 0.0094 15.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EIM89967.1 - 0.0099 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EIM89967.1 - 0.015 15.2 0.1 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EIM89967.1 - 0.019 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EIM89967.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EIM89967.1 - 0.021 15.4 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM89967.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EIM89967.1 - 0.035 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_1N PF02870.15 EIM89967.1 - 0.041 14.7 0.0 0.087 13.6 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Glu_dehyd_C PF16912.5 EIM89967.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 EIM89967.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Ras PF00071.22 EIM89968.1 - 2e-61 206.3 0.2 2.3e-61 206.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM89968.1 - 2.8e-34 117.9 0.1 4e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM89968.1 - 3.9e-12 46.0 0.0 5.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM89968.1 - 6.4e-07 29.5 0.1 9.8e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM89968.1 - 4.8e-05 23.3 0.2 0.009 15.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EIM89968.1 - 0.00034 20.2 0.1 0.0012 18.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EIM89968.1 - 0.0021 18.4 0.0 0.015 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 EIM89968.1 - 0.0061 15.9 0.0 0.0086 15.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIM89968.1 - 0.0093 15.4 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EIM89968.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.7 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EIM89968.1 - 0.014 15.8 0.1 0.024 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EIM89968.1 - 0.024 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EIM89968.1 - 0.027 15.0 0.0 0.044 14.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 EIM89968.1 - 0.05 13.1 0.1 0.15 11.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 EIM89968.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EIM89968.1 - 0.088 12.2 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 EIM89968.1 - 0.096 11.8 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_21 PF13304.6 EIM89968.1 - 0.11 12.2 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system YvfG PF09628.10 EIM89968.1 - 0.16 12.4 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 YvfG protein AAA_5 PF07728.14 EIM89968.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) rhaM PF05336.13 EIM89969.1 - 2.1e-33 114.6 0.0 2.3e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DPBB_1 PF03330.18 EIM89970.1 - 3.6e-08 33.6 0.5 8.4e-08 32.4 0.0 1.9 2 1 1 3 3 3 1 Lytic transglycolase CBM_5_12 PF02839.14 EIM89970.1 - 0.0019 18.7 0.8 0.0019 18.7 0.8 3.2 3 1 0 3 3 3 1 Carbohydrate binding domain Mucin PF01456.17 EIM89970.1 - 0.13 12.2 37.7 0.22 11.5 37.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein VCBS PF13517.6 EIM89971.1 - 9.8e-26 90.1 20.3 8.4e-09 35.9 0.7 5.7 4 2 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EIM89971.1 - 1.6e-10 40.9 14.5 0.23 11.6 0.0 7.1 7 0 0 7 7 7 5 FG-GAP repeat Itfg2 PF15907.5 EIM89971.1 - 0.014 14.5 0.0 0.084 11.9 0.0 2.1 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 CTP_transf_like PF01467.26 EIM89972.1 - 2.7e-06 27.6 0.1 6.7e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EIM89972.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 FAD synthetase Bep_C_terminal PF17841.1 EIM89972.1 - 0.14 12.4 0.1 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DUF3384 PF11864.8 EIM89972.1 - 0.17 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) MARVEL PF01284.23 EIM89973.1 - 0.2 11.7 2.4 0.25 11.3 2.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain SRPRB PF09439.10 EIM89974.1 - 2e-19 69.7 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EIM89974.1 - 5.4e-12 45.5 0.0 7.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIM89974.1 - 4.1e-07 29.6 0.0 5.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIM89974.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM89974.1 - 0.00029 21.2 0.1 0.00048 20.5 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EIM89974.1 - 0.00062 19.4 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EIM89974.1 - 0.0055 16.2 0.0 0.069 12.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 EIM89974.1 - 0.057 13.0 0.0 5 6.6 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 EIM89974.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EIM89974.1 - 0.081 12.3 0.0 0.82 9.1 0.0 2.0 1 1 1 2 2 2 0 Bacterial TniB protein SKG6 PF08693.10 EIM89974.1 - 0.097 12.1 1.8 0.22 11.0 1.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AAA_15 PF13175.6 EIM89974.1 - 0.098 12.4 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 EIM89974.1 - 0.12 12.4 0.1 0.34 11.0 0.0 1.6 1 1 1 2 2 2 0 Dynamin family Pkinase PF00069.25 EIM89975.1 - 1.3e-68 231.2 0.0 1.5e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM89975.1 - 9.3e-33 113.6 0.0 1.1e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM89975.1 - 2.2e-08 33.8 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM89975.1 - 2.6e-05 24.3 0.0 0.0075 16.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EIM89975.1 - 0.00022 20.7 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIM89975.1 - 0.0085 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RAMP4 PF06624.12 EIM89975.1 - 0.074 13.1 0.3 0.18 11.9 0.1 1.7 1 1 0 1 1 1 0 Ribosome associated membrane protein RAMP4 LppA PF16708.5 EIM89976.1 - 0.013 15.5 0.0 5.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium DUF3304 PF11745.8 EIM89976.1 - 0.08 13.4 0.1 16 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3304) Utp21 PF04192.12 EIM89977.1 - 2e-64 217.3 1.9 3.3e-64 216.6 1.9 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EIM89977.1 - 3.2e-16 59.4 0.0 1.2e-05 25.6 0.0 6.9 3 2 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM89977.1 - 3.3e-16 59.4 15.7 0.00061 20.6 0.1 9.7 11 0 0 11 11 11 3 WD domain, G-beta repeat Hira PF07569.11 EIM89977.1 - 0.00031 20.5 1.1 0.19 11.5 0.0 3.9 4 1 0 5 5 5 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EIM89977.1 - 0.00082 18.2 0.7 3.5 6.3 0.2 3.9 2 2 0 3 3 3 2 Nup133 N terminal like RL11D PF11088.8 EIM89977.1 - 0.21 11.9 0.7 0.55 10.5 0.7 1.7 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 PQQ_3 PF13570.6 EIM89977.1 - 0.36 11.4 1.2 15 6.2 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain F-box-like PF12937.7 EIM89978.1 - 0.0036 17.1 0.0 0.046 13.6 0.0 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EIM89978.1 - 0.055 13.4 0.0 0.72 9.8 0.0 2.8 3 0 0 3 3 3 0 F-box domain adh_short PF00106.25 EIM89979.1 - 5.2e-51 172.9 0.8 7.4e-51 172.4 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM89979.1 - 1.4e-34 119.6 0.7 1.9e-34 119.3 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM89979.1 - 9.2e-13 48.5 1.7 1.2e-12 48.1 1.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM89979.1 - 0.00058 19.4 0.5 0.00087 18.8 0.5 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EIM89979.1 - 0.043 13.1 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EIM89979.1 - 0.078 12.4 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 EIM89979.1 - 0.15 11.8 0.6 0.33 10.7 0.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-CCCH PF00642.24 EIM89980.1 - 0.048 13.6 3.4 0.088 12.8 3.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MetOD2 PF18548.1 EIM89980.1 - 0.08 13.1 0.5 0.26 11.4 0.4 1.8 2 0 0 2 2 2 0 Metanogen output domain 2 zf-CCCH_2 PF14608.6 EIM89980.1 - 0.087 13.3 2.3 0.21 12.1 2.3 1.7 1 1 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FAM184 PF15665.5 EIM89980.1 - 1.4 8.7 5.4 1.1 9.0 0.5 2.6 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B DivIC PF04977.15 EIM89980.1 - 2.1 8.2 4.2 0.93 9.3 1.5 1.7 2 0 0 2 2 2 0 Septum formation initiator Abhydrolase_1 PF00561.20 EIM89981.1 - 1.8e-09 37.7 0.2 3.6e-07 30.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM89981.1 - 2.1e-06 27.2 0.0 4e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 EIM89981.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase RWD PF05773.22 EIM89982.1 - 2.9e-18 66.2 0.8 4.7e-18 65.6 0.2 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EIM89982.1 - 8.6e-08 32.6 6.9 2.7e-07 31.0 6.8 1.9 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF1244 PF06844.11 EIM89982.1 - 0.13 12.5 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Peptidase_C37 PF05416.12 EIM89982.1 - 0.22 10.0 3.1 0.27 9.7 3.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ribosomal_S21 PF01165.20 EIM89983.1 - 4e-11 42.5 11.8 6.4e-11 41.8 11.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Cyclin_N PF00134.23 EIM89986.1 - 1.9e-16 60.0 0.2 3.6e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EIM89986.1 - 0.00067 19.6 0.3 0.0014 18.6 0.3 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EIM89986.1 - 0.0094 16.0 0.3 5 7.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain IF-2B PF01008.17 EIM89988.1 - 5.4e-59 199.7 0.0 7.9e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family HrpJ PF07201.11 EIM89988.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 1 1 0 1 1 1 0 HrpJ-like domain Peptidase_M24 PF00557.24 EIM89990.1 - 2.1e-49 168.1 0.0 2.7e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EIM89990.1 - 4e-20 71.9 7.8 6.6e-20 71.1 7.8 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EIM89990.1 - 5.1e-05 23.3 5.3 0.00011 22.2 5.3 1.6 1 0 0 1 1 1 1 MYND finger IMS_C PF11799.8 EIM89990.1 - 0.18 12.5 0.0 0.59 10.8 0.0 1.8 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain Acyltransferase PF01553.21 EIM89992.1 - 2.5e-10 40.1 0.0 3.2e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Exo_endo_phos PF03372.23 EIM89993.1 - 1.4e-08 34.6 0.0 6.5e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 EIM89994.1 - 7.6e-18 64.6 29.2 2.6e-13 49.6 18.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DAD PF02109.16 EIM89994.1 - 0.32 11.3 2.9 0.33 11.3 0.0 2.4 2 0 0 2 2 2 0 DAD family Cofilin_ADF PF00241.20 EIM89995.1 - 2.5e-17 62.8 0.0 2.8e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Slx4 PF09494.10 EIM89995.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease DUF4351 PF14261.6 EIM89995.1 - 0.36 10.9 1.9 11 6.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) Mannosyl_trans PF05007.13 EIM89996.1 - 6.7e-70 235.9 10.0 2.2e-69 234.2 10.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EIM89996.1 - 4.7e-11 42.3 1.1 4.7e-11 42.3 1.1 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EIM89996.1 - 1.6e-07 31.3 12.4 1.6e-07 31.3 12.4 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 87 DUF4538 PF15061.6 EIM89996.1 - 0.13 12.0 0.2 0.3 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF1045 PF06299.12 EIM89996.1 - 0.37 10.7 1.8 1.5 8.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Arf PF00025.21 EIM89997.1 - 6.4e-68 227.6 0.0 7.2e-68 227.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EIM89997.1 - 1.8e-11 43.8 0.0 5.3e-08 32.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EIM89997.1 - 1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EIM89997.1 - 8.4e-08 32.5 0.0 2e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EIM89997.1 - 1.8e-07 31.2 0.0 3.3e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EIM89997.1 - 2e-06 27.5 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EIM89997.1 - 0.00014 21.3 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EIM89997.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Lipase_3 PF01764.25 EIM89998.1 - 9.6e-07 28.8 0.0 3.4e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EIM89998.1 - 0.00032 21.4 0.1 0.00066 20.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EIM89998.1 - 0.035 14.1 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 EIM89998.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Amidohydro_1 PF01979.20 EIM89999.1 - 5.7e-61 206.7 0.0 5.8e-50 170.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EIM89999.1 - 1.1e-06 28.5 0.0 0.023 14.2 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family mRNA_cap_enzyme PF01331.19 EIM90002.1 - 7.8e-53 179.2 0.0 1.1e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EIM90002.1 - 3.2e-31 108.2 0.0 5.8e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EIM90002.1 - 3.6e-07 30.0 0.0 3.5e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EIM90002.1 - 0.0057 17.0 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 1 RNA ligase Pex14_N PF04695.13 EIM90002.1 - 6.5 7.4 9.4 10 6.7 9.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Skp1 PF01466.19 EIM90003.1 - 1.2e-28 99.0 0.7 2e-28 98.2 0.7 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EIM90003.1 - 3.3e-24 84.8 0.9 8.1e-24 83.6 0.1 2.1 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 EIM90003.1 - 0.005 17.1 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF1869 PF08956.10 EIM90003.1 - 0.077 12.9 0.4 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) DUF615 PF04751.14 EIM90003.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF615) Ribosomal_L27 PF01016.19 EIM90004.1 - 3e-34 116.9 1.0 3.9e-34 116.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 EIM90004.1 - 0.028 14.2 0.2 0.11 12.3 0.1 2.1 2 1 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region DUF3074 PF11274.8 EIM90005.1 - 1.1e-44 152.6 0.2 1.6e-44 152.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Gln-synt_C PF00120.24 EIM90006.1 - 1.4e-74 251.2 0.0 3.7e-74 249.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain ANAPC4_WD40 PF12894.7 EIM90007.1 - 3.9e-08 33.5 0.0 0.0032 17.7 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM90007.1 - 4.7e-05 24.1 4.5 0.004 18.0 0.0 4.7 5 1 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 EIM90007.1 - 0.084 12.8 0.0 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.11 EIM90007.1 - 0.12 12.7 0.2 3.6 8.1 0.1 3.4 4 0 0 4 4 4 0 Two component regulator propeller Rubis-subs-bind PF09273.11 EIM90008.1 - 0.022 15.4 0.0 0.041 14.6 0.0 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding SET PF00856.28 EIM90008.1 - 0.031 14.7 0.0 0.09 13.2 0.0 1.8 2 0 0 2 2 2 0 SET domain Asp PF00026.23 EIM90010.1 - 8.4e-34 117.4 2.2 2e-33 116.2 2.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM90010.1 - 1.5e-05 25.3 0.7 0.00011 22.5 0.2 2.0 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EIM90010.1 - 0.0019 18.7 0.0 3.9 8.1 0.0 3.2 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIM90010.1 - 0.028 15.1 0.2 29 5.4 0.1 3.3 2 1 0 2 2 2 0 Aspartyl protease DnaJ PF00226.31 EIM90011.1 - 7.6e-22 77.2 3.3 3.4e-21 75.1 3.3 2.2 1 0 0 1 1 1 1 DnaJ domain TAN PF11640.8 EIM90011.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.8 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair DUF2362 PF10154.9 EIM90011.1 - 9.3 5.1 8.0 1.1 8.1 3.5 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2362) RAI16-like PF10257.9 EIM90012.1 - 1.7e-67 227.8 0.0 3.3e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF2052 PF09747.9 EIM90012.1 - 0.00025 21.2 1.3 0.00075 19.7 1.3 1.8 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 EIM90012.1 - 0.0086 15.1 0.1 0.024 13.6 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EIM90012.1 - 0.025 12.9 4.2 0.046 12.0 4.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 EIM90012.1 - 0.11 11.5 10.6 0.28 10.2 10.6 1.6 1 0 0 1 1 1 0 Paf1 DUF908 PF06012.12 EIM90012.1 - 0.11 11.8 1.9 5.2 6.4 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) CPSF100_C PF13299.6 EIM90012.1 - 0.26 11.4 2.8 0.95 9.6 2.8 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EIM90012.1 - 1.9 8.3 7.6 4.5 7.0 7.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EIM90012.1 - 3.1 7.1 12.1 6.3 6.1 12.1 1.4 1 0 0 1 1 1 0 SDA1 DUF4637 PF15470.6 EIM90012.1 - 3.7 7.3 10.4 9.9 5.9 10.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2098 PF09871.9 EIM90012.1 - 4.3 7.8 6.8 9.4 6.6 6.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DNA_pol_phi PF04931.13 EIM90012.1 - 5.2 5.1 11.1 9.1 4.2 11.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 EIM90012.1 - 5.4 7.3 14.3 0.21 11.9 7.6 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 EIM90012.1 - 6.5 4.8 12.2 10 4.2 12.2 1.2 1 0 0 1 1 1 0 Nop14-like family Glucan_synthase PF02364.15 EIM90013.1 - 0 1320.1 0.0 0 1319.6 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EIM90013.1 - 7.9e-42 142.6 0.1 2.7e-41 140.9 0.1 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NmrA PF05368.13 EIM90015.1 - 5.3e-22 78.5 0.0 9.5e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90015.1 - 2.2e-13 50.5 0.0 3.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EIM90015.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EIM90015.1 - 0.065 12.7 0.0 0.2 11.1 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M49 PF03571.15 EIM90016.1 - 1.1e-225 750.3 0.0 1.3e-225 750.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 EIM90016.1 - 0.046 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain TPR_12 PF13424.6 EIM90017.1 - 0.00019 21.6 5.9 0.93 9.8 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM90017.1 - 0.0023 17.9 0.3 1 9.6 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM90017.1 - 0.0049 17.5 0.1 0.0049 17.5 0.1 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM90017.1 - 0.0095 15.7 0.1 5.6 7.0 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EIM90017.1 - 0.025 14.5 1.1 7.2 6.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIM90017.1 - 0.042 14.5 0.4 2.1 9.2 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM90017.1 - 0.15 11.8 0.1 26 4.6 0.0 2.9 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 EIM90017.1 - 0.7 10.9 8.0 3.1 8.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Cellulase PF00150.18 EIM90018.1 - 4.8e-17 62.3 0.1 2.2e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EIM90018.1 - 0.003 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase GCIP PF13324.6 EIM90019.1 - 1.3e-30 106.9 0.1 4.4e-30 105.2 0.0 1.7 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting DUF1840 PF08895.11 EIM90019.1 - 0.017 15.4 0.2 0.059 13.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) RXT2_N PF08595.11 EIM90019.1 - 0.12 12.4 0.8 0.22 11.5 0.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Microvir_J PF04726.13 EIM90019.1 - 0.12 12.4 1.0 0.26 11.3 1.0 1.4 1 0 0 1 1 1 0 Microvirus J protein Peptidase_M41 PF01434.18 EIM90020.1 - 8.6e-58 195.3 0.0 1.7e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EIM90020.1 - 1.3e-42 145.4 0.0 2.8e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM90020.1 - 9.6e-11 41.3 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIM90020.1 - 5.1e-05 23.7 1.5 0.0023 18.3 1.5 2.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EIM90020.1 - 0.00019 20.8 0.0 0.00046 19.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EIM90020.1 - 0.00037 20.3 0.0 0.00087 19.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EIM90020.1 - 0.00038 20.5 0.2 0.0016 18.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM90020.1 - 0.00039 20.7 0.1 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EIM90020.1 - 0.0013 17.9 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EIM90020.1 - 0.0078 15.8 1.5 0.28 10.8 0.3 2.6 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EIM90020.1 - 0.0095 15.2 0.2 0.019 14.2 0.2 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 EIM90020.1 - 0.013 15.5 0.7 0.068 13.1 0.1 2.3 3 0 0 3 3 2 0 NACHT domain AAA_2 PF07724.14 EIM90020.1 - 0.022 14.9 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EIM90020.1 - 0.026 14.7 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EIM90020.1 - 0.027 13.8 0.3 0.061 12.7 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EIM90020.1 - 0.034 14.2 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EIM90020.1 - 0.04 13.2 0.4 0.17 11.2 0.4 1.9 1 1 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 EIM90020.1 - 0.041 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EIM90020.1 - 0.069 13.7 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIM90020.1 - 0.093 12.2 0.1 0.45 10.0 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EIM90020.1 - 0.099 12.3 0.1 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Beta_protein PF14350.6 EIM90020.1 - 0.12 11.8 0.1 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 Beta protein AAA_28 PF13521.6 EIM90020.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsA PF14450.6 EIM90020.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Cell division protein FtsA Glyco_transf_54 PF04666.13 EIM90020.1 - 0.15 10.9 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region RTA1 PF04479.13 EIM90022.1 - 1.1e-57 195.0 3.0 3.2e-57 193.5 3.0 1.7 1 1 0 1 1 1 1 RTA1 like protein SID-1_RNA_chan PF13965.6 EIM90022.1 - 0.049 12.0 0.3 0.063 11.7 0.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DEAD_2 PF06733.15 EIM90023.1 - 8.7e-54 181.8 0.0 1.5e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EIM90023.1 - 5.6e-47 159.9 1.8 6.2e-42 143.4 0.4 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EIM90023.1 - 1.2e-43 149.2 0.0 2.5e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EIM90023.1 - 0.00051 20.1 0.1 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIM90023.1 - 0.014 15.2 2.3 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase SNF2_N PF00176.23 EIM90023.1 - 0.067 11.9 0.0 2.6 6.7 0.0 2.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.9 EIM90023.1 - 0.13 11.4 0.0 6.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FTHFS PF01268.19 EIM90025.1 - 2.4e-255 848.0 0.0 3.1e-255 847.6 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EIM90025.1 - 2.1e-66 222.2 0.4 2.1e-66 222.2 0.4 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EIM90025.1 - 1.5e-38 131.7 0.4 3.3e-38 130.5 0.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ABC_tran PF00005.27 EIM90026.1 - 1.4e-10 41.8 0.0 2.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIM90026.1 - 0.0003 20.3 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EIM90026.1 - 0.013 15.7 0.1 0.15 12.3 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EIM90026.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Porin_3 PF01459.22 EIM90027.1 - 8.7e-84 281.2 4.7 1e-83 280.9 4.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF3552 PF12072.8 EIM90028.1 - 0.00055 19.4 2.9 0.001 18.5 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF3523 PF12037.8 EIM90028.1 - 0.014 14.8 1.6 0.025 14.0 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Lzipper-MIP1 PF14389.6 EIM90028.1 - 0.038 14.3 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF2721 PF11026.8 EIM90028.1 - 0.053 13.4 3.7 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF3693 PF12472.8 EIM90028.1 - 0.51 10.0 2.5 6.1 6.6 0.1 2.7 3 0 0 3 3 3 0 Phage related protein DUF2418 PF10332.9 EIM90029.1 - 1.7e-29 102.2 0.3 3.9e-29 101.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Ferlin_C PF16165.5 EIM90029.1 - 0.054 13.4 0.9 0.077 12.9 0.0 1.6 2 0 0 2 2 2 0 Ferlin C-terminus FBPase PF00316.20 EIM90030.1 - 2.9e-74 248.6 1.0 3.7e-74 248.3 1.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EIM90030.1 - 0.0038 16.8 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 EIM90031.1 - 1.2e-32 113.3 39.8 1.6e-30 106.2 25.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5336 PF17270.2 EIM90031.1 - 0.088 12.4 0.2 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) DIOX_N PF14226.6 EIM90032.1 - 1.4e-27 96.7 0.0 2.1e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM90032.1 - 4.1e-19 68.9 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5596 PF18082.1 EIM90032.1 - 0.072 12.9 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) MBOAT_2 PF13813.6 EIM90033.1 - 3.3e-13 49.7 1.3 3.3e-13 49.7 1.3 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family zf-C2H2 PF00096.26 EIM90034.1 - 7.7e-13 48.1 12.9 7.3e-07 29.3 1.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM90034.1 - 4.6e-09 36.3 18.0 6.8e-09 35.8 1.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM90034.1 - 6.9e-09 35.8 10.5 0.00061 20.4 0.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EIM90034.1 - 3.5e-06 27.6 0.9 0.0052 17.4 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EIM90034.1 - 1.1e-05 25.5 0.2 0.04 14.2 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM90034.1 - 3.5e-05 24.1 0.4 0.014 15.8 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EIM90034.1 - 0.019 15.3 1.9 0.033 14.5 1.9 1.4 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-CGNR PF11706.8 EIM90034.1 - 0.022 14.6 3.9 0.54 10.2 0.9 2.3 2 0 0 2 2 2 0 CGNR zinc finger zf-C2H2_6 PF13912.6 EIM90034.1 - 0.06 13.4 0.2 0.06 13.4 0.2 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger Toxin_8 PF07365.12 EIM90034.1 - 0.23 11.7 6.3 0.69 10.1 1.9 2.2 1 1 1 2 2 2 0 Alpha conotoxin precursor Pmp3 PF01679.17 EIM90035.1 - 3.3e-16 59.2 4.6 4.4e-16 58.8 4.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PNGaseA PF12222.8 EIM90036.1 - 9.8e-138 459.6 3.4 1.3e-137 459.2 3.4 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A RRM PF10378.9 EIM90036.1 - 0.08 12.7 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative RRM domain Kelch_3 PF13415.6 EIM90037.1 - 0.17 12.2 4.2 0.25 11.7 4.2 1.4 1 1 0 1 1 1 0 Galactose oxidase, central domain Peptidase_M20 PF01546.28 EIM90038.1 - 2e-08 34.2 0.3 2.9e-08 33.6 0.3 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM90038.1 - 9.9e-07 28.7 0.3 2e-06 27.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain HMA PF00403.26 EIM90039.1 - 3.5e-17 62.6 0.2 3.9e-17 62.5 0.2 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain AA_permease_2 PF13520.6 EIM90040.1 - 8.4e-65 219.2 41.3 1e-64 218.9 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIM90040.1 - 2.2e-30 105.7 35.2 2.2e-30 105.7 35.2 1.5 1 1 0 2 2 2 1 Amino acid permease RhoGEF67_u1 PF16615.5 EIM90040.1 - 0.11 13.0 0.8 0.25 11.9 0.8 1.5 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 RNase_PH PF01138.21 EIM90041.1 - 6.9e-32 110.7 0.2 1e-31 110.1 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EIM90041.1 - 0.026 14.5 0.0 0.061 13.4 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 DUF2040 PF09745.9 EIM90042.1 - 7.3e-36 122.9 21.8 7.3e-36 122.9 21.8 3.4 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Pkinase PF00069.25 EIM90043.1 - 5.4e-06 26.0 0.0 2.6e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain RRM_1 PF00076.22 EIM90044.1 - 2.1e-15 56.3 0.1 4.8e-15 55.1 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM90044.1 - 2.3e-08 34.0 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 EIM90044.1 - 0.0068 16.3 0.1 0.0094 15.9 0.1 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EIM90044.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TFIID-18kDa PF02269.16 EIM90045.1 - 1e-20 73.5 0.1 1.5e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF4211 PF13926.6 EIM90046.1 - 6.3e-28 97.6 2.4 2e-27 96.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) UNC-79 PF14776.6 EIM90047.1 - 2.5e-06 26.6 0.1 1.3e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 C1_1 PF00130.22 EIM90047.1 - 7.4e-05 22.6 20.3 9e-05 22.3 9.2 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EIM90047.1 - 0.97 9.4 19.0 2 8.4 3.6 2.6 2 0 0 2 2 2 0 PHD-finger DPM2 PF07297.12 EIM90048.1 - 3.2e-26 91.5 0.3 3.6e-26 91.3 0.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EIM90048.1 - 4.6e-05 23.3 0.3 4.9e-05 23.2 0.3 1.1 1 0 0 1 1 1 1 PIG-P TRAPPC9-Trs120 PF08626.11 EIM90049.1 - 1.3e-199 665.4 0.0 6.4e-198 659.8 0.0 2.0 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit RGCC PF15151.6 EIM90049.1 - 0.025 14.8 0.0 4.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Response gene to complement 32 protein family Bac_rhamnosid_C PF17390.2 EIM90049.1 - 0.088 12.6 0.3 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain TPR_12 PF13424.6 EIM90049.1 - 0.21 11.9 0.2 8.2 6.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.23 EIM90050.1 - 4.1e-109 364.5 0.2 1.9e-108 362.4 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EIM90050.1 - 2.3e-24 86.0 0.2 1.8e-23 83.2 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EIM90050.1 - 0.00023 21.5 0.8 0.00023 21.5 0.8 4.3 3 1 1 4 4 4 1 Kinesin-associated microtubule-binding GlnE PF03710.15 EIM90050.1 - 0.061 12.7 4.2 0.14 11.5 4.2 1.7 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase RasGAP_C PF03836.15 EIM90050.1 - 0.79 9.9 7.4 1.2 9.3 2.0 3.2 2 2 0 2 2 2 0 RasGAP C-terminus Elf1 PF05129.13 EIM90051.1 - 3.5e-30 103.9 0.7 4.3e-30 103.6 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 EIM90051.1 - 0.0069 15.8 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Nup96 PF12110.8 EIM90051.1 - 0.012 14.7 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 zf-CHY PF05495.12 EIM90051.1 - 0.017 15.6 1.3 0.024 15.1 1.3 1.2 1 0 0 1 1 1 0 CHY zinc finger zf-Sec23_Sec24 PF04810.15 EIM90051.1 - 0.027 14.5 0.5 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Kinesin PF00225.23 EIM90052.1 - 2e-112 375.4 0.2 5.8e-112 373.9 0.2 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIM90052.1 - 2.7e-27 95.6 0.0 9.7e-27 93.7 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 EIM90052.1 - 4.2e-08 33.1 2.0 4.2e-08 33.1 2.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF465) TMF_TATA_bd PF12325.8 EIM90052.1 - 0.013 15.7 5.5 0.013 15.7 5.5 6.0 2 1 4 6 6 6 0 TATA element modulatory factor 1 TATA binding FtsK_SpoIIIE PF01580.18 EIM90052.1 - 0.68 9.2 11.9 0.21 10.9 0.4 4.1 2 1 0 4 4 4 0 FtsK/SpoIIIE family TFA2_Winged_2 PF18121.1 EIM90052.1 - 0.93 9.2 3.9 8.2 6.2 1.5 3.6 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 PUF PF00806.19 EIM90053.1 - 1.6e-66 216.4 7.9 1.2e-10 40.5 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 EIM90053.1 - 0.0018 18.6 1.7 0.32 11.3 0.0 3.8 2 2 3 5 5 5 1 CPL (NUC119) domain sCache_2 PF17200.4 EIM90053.1 - 0.0022 17.9 0.0 2.7 7.8 0.0 4.0 3 1 1 4 4 4 1 Single Cache domain 2 DUF234 PF03008.14 EIM90053.1 - 0.27 11.7 0.7 76 3.9 0.0 3.6 4 0 0 4 4 4 0 Archaea bacterial proteins of unknown function Sec16 PF12932.7 EIM90054.1 - 7.5e-28 97.5 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_C PF12931.7 EIM90054.1 - 4.9e-27 95.4 0.1 9.2e-27 94.5 0.0 1.4 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 OST3_OST6 PF04756.13 EIM90055.1 - 1.4e-94 316.8 0.1 1.5e-94 316.6 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EIM90055.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF998 PF06197.13 EIM90055.1 - 0.0087 15.7 11.0 0.0093 15.6 9.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF998) 7TMR-DISM_7TM PF07695.11 EIM90055.1 - 2.2 8.1 17.2 8.1 6.3 17.2 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling VKOR PF07884.14 EIM90055.1 - 4.4 7.5 8.2 1.9 8.7 1.3 2.2 2 0 0 2 2 2 0 Vitamin K epoxide reductase family PI3_PI4_kinase PF00454.27 EIM90056.1 - 1.2e-33 117.0 0.0 2.3e-32 112.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Glyco_transf_15 PF01793.16 EIM90057.1 - 9e-123 409.7 5.3 1.1e-122 409.4 5.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 EIM90058.1 - 3.4e-125 417.6 2.7 4.3e-125 417.3 2.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase KAR9 PF08580.10 EIM90059.1 - 4.7 5.6 7.9 6.9 5.1 7.9 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Helitron_like_N PF14214.6 EIM90060.1 - 1.8e-35 122.9 0.0 3.5e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EIM90061.1 - 3.7e-12 46.1 0.0 3.1e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EIM90061.1 - 3.9e-05 23.5 0.0 0.00085 19.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain MFS_1 PF07690.16 EIM90062.1 - 2.6e-22 79.2 39.5 3.5e-22 78.8 39.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG16 PF08614.11 EIM90063.1 - 0.0012 19.1 6.2 0.0012 19.1 6.2 3.5 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) DUF3632 PF12311.8 EIM90063.1 - 0.0084 16.6 0.4 0.0084 16.6 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) YabA PF06156.13 EIM90063.1 - 0.014 16.0 3.1 0.014 16.0 3.1 4.0 4 1 0 4 4 4 0 Initiation control protein YabA CLZ PF16526.5 EIM90063.1 - 0.22 11.9 11.2 0.23 11.8 0.5 3.5 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TSC22 PF01166.18 EIM90063.1 - 0.24 11.7 10.2 1.2 9.5 1.4 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Nsp1_C PF05064.13 EIM90063.1 - 0.34 10.7 8.7 0.68 9.7 0.6 2.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region Spidroin_N PF16763.5 EIM90063.1 - 0.87 9.6 5.3 1.4 9.0 0.1 3.1 2 1 1 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term JIP_LZII PF16471.5 EIM90063.1 - 1.9 8.7 10.6 0.52 10.5 6.0 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 EIM90063.1 - 2.6 8.1 15.5 0.72 9.9 3.9 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Tho2 PF11262.8 EIM90063.1 - 5.9 6.0 15.4 1.6 7.8 2.2 2.8 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Ferric_reduct PF01794.19 EIM90064.1 - 1.2e-20 73.9 13.3 1.2e-20 73.9 13.3 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EIM90064.1 - 5e-16 59.2 0.0 5.3e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIM90064.1 - 3e-11 43.4 0.0 7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4449 PF14613.6 EIM90065.1 - 5.3e-08 33.1 6.1 5.1e-07 30.0 0.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) U1snRNP70_N PF12220.8 EIM90065.1 - 3.9 8.2 6.6 17 6.2 0.5 3.4 4 0 0 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TRM PF02005.16 EIM90067.1 - 2.8e-123 411.9 0.0 3.6e-123 411.5 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase AsmA_2 PF13502.6 EIM90067.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region TFIIS_C PF01096.18 EIM90067.1 - 0.25 11.2 1.9 4.8 7.1 0.1 2.8 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Pkinase PF00069.25 EIM90068.1 - 6.2e-70 235.6 0.0 8.6e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90068.1 - 2.7e-47 161.2 0.0 4.6e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 EIM90068.1 - 4.6e-15 55.8 0.1 9.2e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EIM90068.1 - 9.6e-14 51.2 0.1 1.8e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 EIM90068.1 - 2.1e-12 47.2 0.0 4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 EIM90068.1 - 2.8e-06 26.9 0.0 0.00024 20.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SAM_4 PF18017.1 EIM90068.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2020 PF09449.10 EIM90068.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) Pkinase_fungal PF17667.1 EIM90068.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SDA1 PF05285.12 EIM90068.1 - 0.27 10.6 12.6 0.51 9.7 12.6 1.4 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EIM90068.1 - 2.5 6.6 4.2 5.6 5.4 4.2 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EIM90068.1 - 2.7 6.2 5.3 3.8 5.7 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 EIM90068.1 - 3 7.6 9.9 6.7 6.4 9.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 EIM90068.1 - 6.8 6.2 20.5 14 5.2 20.5 1.5 1 1 0 1 1 1 0 PPP4R2 Alpha-amylase PF00128.24 EIM90069.1 - 7.6e-26 91.5 0.0 1.6e-24 87.1 0.0 2.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EIM90069.1 - 1.3e-15 57.7 0.0 2.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EIM90069.1 - 4.5e-08 32.8 0.0 8.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EIM90069.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Histone PF00125.24 EIM90070.1 - 2.7e-22 79.5 4.3 3.7e-22 79.1 4.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIM90070.1 - 1.5e-06 28.4 0.1 3.4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EIM90070.1 - 0.00044 20.7 0.0 0.00073 20.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EIM90070.1 - 0.0023 18.0 0.9 0.0028 17.7 0.9 1.1 1 0 0 1 1 1 1 YscO-like protein DUF1018 PF06252.12 EIM90070.1 - 0.028 15.4 1.2 0.047 14.7 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.11 EIM90070.1 - 0.084 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Methyltransf_11 PF08241.12 EIM90071.1 - 6.7e-17 61.9 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM90071.1 - 1.6e-13 51.2 0.0 4.1e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM90071.1 - 3.3e-09 37.4 0.0 6.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM90071.1 - 2.7e-06 27.3 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM90071.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EIM90071.1 - 0.021 14.6 0.0 0.049 13.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MaoC_dehydratas PF01575.19 EIM90072.1 - 4.7e-05 23.0 0.0 8.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Histone PF00125.24 EIM90073.1 - 1.2e-20 74.2 7.1 1.6e-20 73.8 7.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIM90073.1 - 6.2e-05 23.2 0.6 0.00019 21.6 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EIM90073.1 - 0.028 14.1 1.3 0.64 9.6 0.0 2.4 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 EIM90073.1 - 0.061 13.8 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CCDC106 PF15794.5 EIM90073.1 - 0.11 12.3 9.1 0.14 11.9 9.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PRC2_HTH_1 PF18118.1 EIM90073.1 - 1.4 9.7 5.9 1 10.2 4.3 1.6 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Connexin PF00029.19 EIM90073.1 - 1.5 8.6 3.8 1.8 8.3 3.6 1.4 1 1 0 1 1 1 0 Connexin PRCC PF10253.9 EIM90074.1 - 1.2e-30 107.9 13.9 1.2e-30 107.9 13.9 3.4 1 1 2 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Nucleoporin_C PF03177.14 EIM90075.1 - 3.5e-66 224.2 0.0 4.3e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EIM90075.1 - 3e-14 52.6 0.0 4.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.8 EIM90075.1 - 0.067 11.8 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Zn_clus PF00172.18 EIM90076.1 - 0.57 10.4 11.7 3.1 8.0 1.4 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP PF02037.27 EIM90077.1 - 4.6e-12 45.4 0.3 1.2e-11 44.0 0.2 1.8 2 0 0 2 2 2 1 SAP domain SPX PF03105.19 EIM90077.1 - 0.12 12.3 2.9 0.16 11.9 2.9 1.1 1 0 0 1 1 1 0 SPX domain OTT_1508_deam PF14441.6 EIM90079.1 - 5e-17 61.7 1.7 7.5e-17 61.1 1.2 1.6 2 0 0 2 2 2 1 OTT_1508-like deaminase WD40 PF00400.32 EIM90080.1 - 9.5e-07 29.4 8.5 0.055 14.4 0.4 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat IATP PF04568.12 EIM90081.1 - 0.00053 20.4 3.2 0.00066 20.1 3.0 1.3 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF4662 PF15578.6 EIM90081.1 - 0.064 13.0 2.1 0.069 12.9 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Cellulase PF00150.18 EIM90082.1 - 2.1e-11 43.8 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RAP1 PF07218.11 EIM90082.1 - 2.5 6.3 9.4 3.4 5.8 9.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PCM1_C PF15717.5 EIM90083.1 - 0.84 8.3 7.2 1.3 7.6 7.2 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus NPR3 PF03666.13 EIM90083.1 - 5.9 5.6 7.7 9.5 4.9 7.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2367 PF10164.9 EIM90084.1 - 3.8e-09 37.0 4.1 3.8e-09 37.0 4.1 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) COPI_assoc PF08507.10 EIM90084.1 - 0.073 13.1 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 COPI associated protein PepSY_TM PF03929.16 EIM90084.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region zf-LITAF-like PF10601.9 EIM90084.1 - 0.19 12.0 2.4 0.29 11.4 2.4 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain WD40 PF00400.32 EIM90085.1 - 8.3e-44 146.7 22.3 1.5e-07 32.0 0.2 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90085.1 - 2.9e-16 59.5 2.8 2.1e-07 31.2 0.2 4.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM90085.1 - 4.7e-08 32.1 6.8 0.023 13.4 0.0 4.7 3 1 2 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EIM90085.1 - 0.00088 18.9 0.6 0.2 11.2 0.2 2.4 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 EIM90085.1 - 0.0017 17.4 1.1 5.2 5.9 0.0 3.4 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 EIM90085.1 - 0.014 15.3 0.0 0.051 13.6 0.0 1.8 2 0 0 2 2 2 0 LisH eIF2A PF08662.11 EIM90085.1 - 0.082 12.8 3.6 1.2 9.0 0.1 3.1 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Pox_A_type_inc PF04508.12 EIM90085.1 - 0.86 9.6 3.7 0.28 11.1 0.5 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Chromo PF00385.24 EIM90086.1 - 7.7e-12 44.9 3.8 1.4e-11 44.1 3.8 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MFS_1 PF07690.16 EIM90087.1 - 4.3e-30 104.8 30.2 4.3e-30 104.8 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ndc1_Nup PF09531.10 EIM90087.1 - 1.1 7.9 3.8 0.36 9.5 0.2 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SNF2_N PF00176.23 EIM90088.1 - 4.2e-55 186.9 0.0 6.7e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EIM90088.1 - 3.2e-43 148.0 3.9 6.1e-43 147.1 3.9 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EIM90088.1 - 3.6e-16 59.5 0.0 8.5e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM90088.1 - 1.7e-06 28.1 0.0 6.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIM90088.1 - 7.6e-06 25.3 0.0 4.1e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EIM90088.1 - 7.9e-06 25.3 0.1 1.3e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase GYF PF02213.16 EIM90089.1 - 4.2e-07 29.5 1.9 4.2e-07 29.5 1.9 1.8 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 EIM90089.1 - 0.04 13.7 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 GYF domain 2 Oxysterol_BP PF01237.18 EIM90089.1 - 0.73 8.6 7.2 1.1 8.0 7.2 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein CDC45 PF02724.14 EIM90089.1 - 6.7 4.9 13.0 8.6 4.5 13.0 1.3 1 0 0 1 1 1 0 CDC45-like protein PQ-loop PF04193.14 EIM90090.1 - 8.8e-36 121.5 11.8 3.5e-19 68.3 0.3 2.6 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 EIM90090.1 - 0.25 11.4 2.9 0.24 11.5 0.4 2.0 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange CLTH PF10607.9 EIM90091.1 - 1.1e-15 57.8 0.0 1.4e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EIM90091.1 - 0.0068 16.3 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 LisH Ribosomal_L31 PF01197.18 EIM90091.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 LRR_6 PF13516.6 EIM90092.1 - 0.03 14.4 0.1 0.35 11.0 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich repeat LRR_4 PF12799.7 EIM90092.1 - 0.045 14.2 0.1 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM90092.1 - 0.078 12.8 0.1 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Leucine rich repeat DUF3723 PF12520.8 EIM90094.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) NCE101 PF11654.8 EIM90095.1 - 1.8e-19 69.1 0.0 2.5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 NatB_MDM20 PF09797.9 EIM90096.1 - 4.8e-68 229.8 2.8 4.8e-68 229.8 2.8 1.8 2 1 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EIM90096.1 - 9.4e-07 29.3 0.9 0.12 12.9 0.4 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM90096.1 - 2.8e-05 24.5 2.1 0.99 10.4 0.0 6.3 5 1 2 7 7 7 1 Tetratricopeptide repeat UreF PF01730.16 EIM90096.1 - 0.0034 18.0 0.1 9.4 6.8 0.0 3.6 3 0 0 3 3 3 1 UreF TPR_16 PF13432.6 EIM90096.1 - 0.015 16.0 0.0 8.8 7.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EIM90096.1 - 0.019 14.4 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit ANAPC3 PF12895.7 EIM90096.1 - 0.074 13.3 0.9 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EIM90096.1 - 0.12 12.9 4.0 0.31 11.5 0.0 3.5 3 1 0 3 3 3 0 Bacterial transcriptional activator domain RPA_C PF08784.11 EIM90097.1 - 4.4e-13 49.8 0.3 1.9e-12 47.7 0.0 2.1 2 1 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EIM90097.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lipase_GDSL_2 PF13472.6 EIM90098.1 - 9.9e-06 26.1 0.1 1.7e-05 25.3 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIM90098.1 - 0.00037 20.5 0.0 0.00073 19.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ATG_C PF09333.11 EIM90099.1 - 1.5e-36 124.6 0.1 3.5e-36 123.4 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EIM90099.1 - 1.2e-11 44.7 0.0 3.8e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EIM90099.1 - 2.7e-10 40.2 0.0 1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 EIM90099.1 - 1.1e-05 25.3 0.2 0.0003 20.6 0.0 2.5 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Ribosomal_L24e PF01246.20 EIM90100.1 - 4.5e-32 110.1 6.8 4.5e-32 110.1 6.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e HAGH_C PF16123.5 EIM90100.1 - 0.036 14.6 1.5 0.061 13.9 0.7 1.8 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus zf-FCS PF06467.14 EIM90100.1 - 0.042 13.8 4.1 0.089 12.8 4.1 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif RyR PF02026.16 EIM90100.1 - 0.058 13.6 0.5 0.098 12.9 0.5 1.4 1 0 0 1 1 1 0 RyR domain Cytochrom_C550 PF14495.6 EIM90100.1 - 0.06 13.1 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-550 domain SH2_2 PF14633.6 EIM90101.1 - 1.7e-77 259.7 0.0 1.7e-77 259.7 0.0 2.3 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 EIM90101.1 - 2.8e-29 101.5 0.0 5.5e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EIM90101.1 - 1.9e-25 89.4 0.0 4.6e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 EIM90101.1 - 4.8e-23 81.8 0.7 1.2e-22 80.5 0.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 EIM90101.1 - 3e-21 75.8 32.2 3e-21 75.8 32.2 5.8 4 1 2 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.24 EIM90101.1 - 6.6e-08 32.5 0.0 1.7e-05 24.8 0.0 3.5 3 0 0 3 3 3 1 SH2 domain HHH_9 PF17674.1 EIM90101.1 - 1.2e-06 29.3 0.1 4.6e-06 27.4 0.1 2.1 1 0 0 1 1 1 1 HHH domain HHH_3 PF12836.7 EIM90101.1 - 0.0033 17.7 0.0 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.23 EIM90101.1 - 0.014 15.7 1.0 0.034 14.5 1.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain Tex_N PF09371.10 EIM90101.1 - 0.015 15.0 1.0 0.08 12.6 0.0 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain ABC2_membrane_5 PF13346.6 EIM90102.1 - 0.048 13.2 0.3 0.069 12.7 0.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SRP54 PF00448.22 EIM90103.1 - 2e-72 243.0 1.7 3.4e-72 242.2 1.7 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EIM90103.1 - 7.4e-31 106.7 0.9 7.4e-31 106.7 0.9 4.2 4 1 1 5 5 2 1 Signal peptide binding domain SRP54_N PF02881.19 EIM90103.1 - 5e-19 68.3 6.0 1.2e-18 67.1 6.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 EIM90103.1 - 0.00038 20.6 0.1 0.0008 19.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EIM90103.1 - 0.00092 19.6 0.2 0.00092 19.6 0.2 2.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EIM90103.1 - 0.0023 17.2 0.1 0.0046 16.3 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 EIM90103.1 - 0.012 15.7 0.0 0.037 14.1 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EIM90103.1 - 0.015 14.3 0.7 0.015 14.3 0.7 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EIM90103.1 - 0.04 13.6 2.8 0.049 13.3 0.1 2.5 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 EIM90103.1 - 0.06 13.1 0.3 0.33 10.7 0.1 2.1 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRPRB PF09439.10 EIM90103.1 - 0.27 10.6 2.6 14 5.0 0.1 2.8 3 1 1 4 4 4 0 Signal recognition particle receptor beta subunit HTH_ParB PF17762.1 EIM90103.1 - 0.48 10.3 2.1 8.2 6.3 0.3 2.7 2 0 0 2 2 2 0 HTH domain found in ParB protein WD40 PF00400.32 EIM90104.1 - 6.2e-14 52.2 16.7 0.0014 19.4 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90104.1 - 0.0072 16.6 0.1 18 5.7 0.0 3.9 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 EIM90105.1 - 3.5e-14 53.0 0.0 6.9e-14 52.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM90105.1 - 6.2e-12 46.1 0.0 1.7e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM90105.1 - 3.6e-10 40.3 0.0 9.9e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM90105.1 - 1.5e-08 34.5 0.0 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EIM90105.1 - 1.3e-05 25.9 0.0 0.00027 21.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EIM90105.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 EIM90105.1 - 0.00084 18.8 0.0 0.0054 16.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EIM90105.1 - 0.0029 17.2 0.0 0.0071 15.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EIM90105.1 - 0.005 16.2 0.0 0.76 9.1 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EIM90105.1 - 0.0096 14.5 0.0 0.015 13.8 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 EIM90105.1 - 0.012 14.9 0.0 0.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EIM90105.1 - 0.025 13.9 0.0 0.076 12.3 0.0 1.8 2 1 0 2 2 2 0 O-methyltransferase domain FtsJ PF01728.19 EIM90105.1 - 0.057 13.5 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RRM_1 PF00076.22 EIM90106.1 - 2.8e-80 264.1 3.6 3.1e-21 75.0 0.6 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EIM90106.1 - 4.4e-26 90.9 2.9 1.4e-25 89.2 2.9 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 EIM90106.1 - 2e-06 27.6 0.0 0.03 14.2 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EIM90106.1 - 7.8e-05 22.6 1.5 3.3 7.8 0.0 4.6 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EIM90106.1 - 0.0014 18.6 6.9 0.99 9.5 2.0 3.5 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 EIM90106.1 - 0.0063 16.6 0.4 0.72 10.0 0.1 3.1 3 0 0 3 3 3 1 Limkain b1 DUF4407 PF14362.6 EIM90106.1 - 0.011 15.1 1.5 0.016 14.6 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YflT PF11181.8 EIM90106.1 - 0.022 15.3 4.6 0.58 10.7 0.7 2.9 3 0 0 3 3 3 0 Heat induced stress protein YflT ArAE_1_C PF11728.8 EIM90106.1 - 0.038 14.0 2.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain OB_RNB PF08206.11 EIM90106.1 - 0.043 13.5 1.0 18 5.1 0.2 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain SET_assoc PF11767.8 EIM90106.1 - 0.11 12.1 0.1 25 4.6 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Nefa_Nip30_N PF10187.9 EIM90106.1 - 0.72 10.2 5.9 0.34 11.3 0.4 2.5 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SCAMP PF04144.13 EIM90107.1 - 6.3e-52 176.4 9.3 7.3e-52 176.2 9.3 1.0 1 0 0 1 1 1 1 SCAMP family DUF3318 PF11780.8 EIM90107.1 - 0.035 14.1 1.2 0.065 13.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF3552 PF12072.8 EIM90107.1 - 0.34 10.3 3.0 0.55 9.6 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DPBB_1 PF03330.18 EIM90108.1 - 1.4e-06 28.4 0.3 4.3e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EIM90108.1 - 0.00068 19.5 0.2 0.0021 17.9 0.2 1.8 1 0 0 1 1 1 1 Barwin family Epimerase PF01370.21 EIM90109.1 - 1.8e-08 34.2 0.0 6.3e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM90109.1 - 1.5e-06 28.2 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIM90109.1 - 0.00033 20.2 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIM90109.1 - 0.0005 19.2 0.0 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EIM90109.1 - 0.026 13.6 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 EIM90109.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase ADK PF00406.22 EIM90110.1 - 3.2e-43 147.4 0.0 4.3e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EIM90110.1 - 7.3e-17 62.1 0.0 1.5e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EIM90110.1 - 7e-14 51.5 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EIM90110.1 - 1.6e-05 25.5 0.0 3.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIM90110.1 - 0.006 16.8 0.0 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 EIM90110.1 - 0.048 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Methyltransf_PK PF05891.12 EIM90111.1 - 1.4e-47 162.0 0.0 4.4e-28 98.3 0.1 3.0 2 2 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EIM90111.1 - 4.4e-05 24.1 0.0 0.55 11.0 0.0 2.9 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EIM90111.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM90111.1 - 0.0018 18.9 0.0 1.3 9.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EIM90111.1 - 0.051 14.3 0.0 0.34 11.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Swi3 PF07962.12 EIM90112.1 - 1e-27 95.9 0.1 1.9e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 IHABP4_N PF16174.5 EIM90112.1 - 0.045 14.4 1.2 0.045 14.4 1.2 3.8 3 1 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal Glyco_transf_18 PF15024.6 EIM90113.1 - 1e-11 44.2 0.0 1.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 18 HSA PF07529.13 EIM90114.1 - 1.8e-14 53.8 0.9 1.8e-14 53.8 0.9 3.9 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 EIM90114.1 - 2.5e-06 27.6 0.2 6.6e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EIM90114.1 - 0.00021 21.4 1.6 0.00046 20.3 1.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EIM90114.1 - 0.005 17.0 0.7 0.005 17.0 0.7 2.1 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 YdfA_immunity PF12127.8 EIM90114.1 - 0.79 8.7 4.1 1.5 7.8 4.1 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial SMI1_KNR4 PF09346.10 EIM90115.1 - 1.2e-26 93.7 0.0 2.4e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) CoA_trans PF01144.23 EIM90116.1 - 8.8e-103 342.3 2.9 3e-60 203.3 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EIM90116.1 - 0.0025 17.8 0.1 0.0048 16.9 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_35 PF01301.19 EIM90117.1 - 1.6e-86 290.8 0.3 2.2e-86 290.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EIM90117.1 - 2.9e-55 185.7 0.4 2.2e-30 105.6 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EIM90117.1 - 1.6e-38 132.3 0.6 2.9e-38 131.5 0.6 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EIM90117.1 - 6e-15 54.6 0.0 1.9e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 CoA_trans PF01144.23 EIM90118.1 - 1.6e-104 348.1 1.1 1.1e-66 224.4 0.4 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EIM90118.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cofilin_ADF PF00241.20 EIM90119.1 - 8.3e-35 119.2 0.0 1.1e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein FYVE PF01363.21 EIM90120.1 - 6.8e-18 64.6 1.1 1.1e-17 63.9 1.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 EIM90120.1 - 1.1e-14 53.8 0.7 2.4e-14 52.8 0.7 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.13 EIM90120.1 - 0.062 13.3 5.3 0.14 12.1 5.3 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.16 EIM90120.1 - 0.089 13.0 0.6 0.22 11.7 0.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_2 PF14445.6 EIM90120.1 - 0.37 11.0 1.3 0.76 10.0 1.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Sec66 PF09802.9 EIM90121.1 - 1.7e-57 193.9 0.0 1.9e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Citrate_synt PF00285.21 EIM90122.1 - 1.7e-96 323.4 0.0 2.1e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain B56 PF01603.20 EIM90124.1 - 2.8e-191 636.0 4.9 3.3e-191 635.7 4.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Recep_L_domain PF01030.24 EIM90124.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Receptor L domain HSP70 PF00012.20 EIM90125.1 - 1.3e-264 879.0 4.2 1.5e-264 878.8 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIM90125.1 - 1.2e-15 57.2 0.0 1.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EIM90125.1 - 0.0027 17.5 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EIM90125.1 - 0.015 14.5 0.4 0.047 12.9 0.4 1.8 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase HOIP-UBA PF16678.5 EIM90125.1 - 0.073 13.1 0.1 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 HOIP UBA domain pair StbA PF06406.11 EIM90125.1 - 0.094 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein PhoD PF09423.10 EIM90126.1 - 1.4e-98 330.2 2.5 1.7e-98 329.9 2.5 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EIM90126.1 - 8e-24 84.0 0.0 1.6e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EIM90126.1 - 0.00022 21.7 0.1 0.00063 20.3 0.1 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DEAD PF00270.29 EIM90127.1 - 1.8e-38 132.0 0.0 4.7e-38 130.7 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EIM90127.1 - 1.1e-23 83.2 0.4 2.6e-23 82.0 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EIM90127.1 - 3.5e-19 69.2 0.0 8.3e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM90127.1 - 2.8e-05 24.2 0.0 8.9e-05 22.6 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIM90127.1 - 0.062 13.6 0.2 0.32 11.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 EIM90128.1 - 6.6e-15 54.9 0.0 1.3e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM90128.1 - 0.003 17.6 11.3 0.0077 16.3 11.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 EIM90128.1 - 0.33 11.1 1.5 0.78 9.9 1.5 1.7 1 0 0 1 1 1 0 Basic region leucine zipper SOG2 PF10428.9 EIM90129.1 - 8.1e-98 328.8 5.3 8.1e-98 328.8 5.3 2.6 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 EIM90129.1 - 1.9e-12 46.7 2.4 5.2e-08 32.5 0.3 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EIM90129.1 - 2e-10 40.7 7.7 1.4e-05 25.4 0.4 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIM90129.1 - 0.04 14.4 2.8 41 5.3 0.1 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat MukB PF04310.12 EIM90129.1 - 0.2 11.5 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal USP7_ICP0_bdg PF12436.8 EIM90130.1 - 7e-89 297.3 0.2 8.6e-88 293.7 0.1 2.5 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EIM90130.1 - 8.4e-69 231.4 0.9 2.1e-64 217.0 0.1 3.8 2 1 2 4 4 4 3 Ubiquitin-specific protease C-terminal UCH PF00443.29 EIM90130.1 - 6.2e-48 163.5 0.0 9.5e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM90130.1 - 2.6e-19 70.0 0.0 8e-19 68.4 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EIM90130.1 - 2.8e-07 30.7 0.0 1.3e-06 28.6 0.0 2.1 1 0 0 1 1 1 1 MATH domain ubiquitin PF00240.23 EIM90130.1 - 0.1 12.4 1.3 4 7.3 0.0 4.2 6 0 0 6 6 6 0 Ubiquitin family Thioredoxin PF00085.20 EIM90131.1 - 8.1e-25 86.8 0.0 8.8e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIM90131.1 - 6.7e-08 33.0 0.1 2.6e-07 31.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIM90131.1 - 2.2e-05 24.7 0.0 4.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EIM90131.1 - 4.2e-05 23.3 0.1 5e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EIM90131.1 - 0.0011 18.9 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EIM90131.1 - 0.015 14.6 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 EIM90131.1 - 0.017 14.8 0.1 0.022 14.5 0.1 1.3 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 EIM90131.1 - 0.024 14.8 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 EIM90131.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin DNA_primase_lrg PF04104.14 EIM90133.1 - 9.6e-87 290.7 0.0 1.3e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Ion_trans PF00520.31 EIM90134.1 - 0.00021 20.6 0.5 0.00027 20.2 0.5 1.1 1 0 0 1 1 1 1 Ion transport protein APG6_N PF17675.1 EIM90134.1 - 0.0035 17.9 3.0 0.0045 17.5 3.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region RIX1 PF08167.12 EIM90134.1 - 0.036 13.8 0.5 0.74 9.5 0.0 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HIP1_clath_bdg PF16515.5 EIM90134.1 - 0.062 13.9 4.7 0.1 13.2 4.7 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3847 PF12958.7 EIM90134.1 - 0.074 13.2 4.9 0.12 12.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DivIC PF04977.15 EIM90134.1 - 1.8 8.4 4.7 3.2 7.6 4.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF1524 PF07510.11 EIM90136.1 - 3.8e-08 33.3 0.0 5.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) FUN14 PF04930.15 EIM90137.1 - 1e-19 70.7 1.2 1.7e-19 70.0 1.2 1.3 1 0 0 1 1 1 1 FUN14 family Methyltr_RsmB-F PF01189.17 EIM90138.1 - 3.6e-76 255.3 0.0 5.2e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EIM90138.1 - 4.8e-08 33.4 0.0 1.4e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 EIM90138.1 - 0.0019 18.0 0.3 0.0051 16.6 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein PCMT PF01135.19 EIM90138.1 - 0.003 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EIM90138.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EIM90138.1 - 0.038 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 EIM90138.1 - 0.061 14.0 0.0 0.18 12.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain SUR7 PF06687.12 EIM90140.1 - 1.2e-17 64.3 16.5 1.7e-17 63.7 16.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 EIM90140.1 - 0.2 11.1 12.3 6.3 6.2 7.3 3.1 2 1 0 2 2 2 0 Clc-like DUF1385 PF07136.11 EIM90140.1 - 0.82 8.9 5.4 0.065 12.5 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Prominin PF05478.11 EIM90140.1 - 1.9 6.4 3.6 1.4 6.8 2.0 1.5 1 1 0 1 1 1 0 Prominin W2 PF02020.18 EIM90142.1 - 6.8e-11 42.2 0.6 6.8e-11 42.2 0.6 4.5 3 2 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EIM90142.1 - 6e-08 32.1 12.9 0.0008 19.0 1.2 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EIM90142.1 - 2.2e-07 30.7 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EIM90142.1 - 0.0002 21.7 0.0 0.00042 20.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EIM90142.1 - 0.00027 20.0 0.1 0.00051 19.1 0.1 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 EIM90142.1 - 0.0016 18.1 12.7 0.009 15.7 4.7 3.4 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase SDA1 PF05285.12 EIM90142.1 - 0.54 9.6 47.0 0.36 10.2 23.1 2.5 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 EIM90142.1 - 0.88 8.8 52.0 0.011 15.1 17.1 2.1 2 0 0 2 2 2 0 BUD22 Pmp3 PF01679.17 EIM90143.1 - 1.2e-06 28.6 0.4 2.3e-06 27.7 0.4 1.5 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Aminotran_5 PF00266.19 EIM90144.1 - 3.2e-11 42.8 0.0 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.19 EIM90145.1 - 2.1e-16 60.1 0.0 2.8e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EIM90145.1 - 0.00017 20.9 0.0 0.0043 16.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM90145.1 - 0.00029 20.5 0.0 0.013 15.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM90145.1 - 0.00067 19.8 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EIM90145.1 - 0.00095 19.7 0.0 0.035 14.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EIM90145.1 - 0.0027 16.8 0.1 0.024 13.7 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.6 EIM90145.1 - 0.0087 15.3 0.1 1.7 7.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM90145.1 - 0.011 14.5 0.0 0.19 10.4 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EIM90145.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EIM90145.1 - 0.051 14.1 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Trp_halogenase PF04820.14 EIM90145.1 - 0.12 11.2 0.1 6.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Glu_dehyd_C PF16912.5 EIM90145.1 - 0.13 11.7 0.0 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus AT_hook PF02178.19 EIM90146.1 - 0.02 14.7 44.2 0.41 10.7 10.6 3.7 3 0 0 3 3 3 0 AT hook motif PRKCSH PF07915.13 EIM90147.1 - 2.4e-12 47.6 0.0 6.8e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EIM90147.1 - 2.2e-05 24.2 0.0 0.00021 21.0 0.0 2.2 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Pkinase PF00069.25 EIM90148.1 - 5.2e-45 153.9 0.0 1.8e-44 152.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90148.1 - 1.5e-26 93.2 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM90148.1 - 0.0091 15.9 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family adh_short PF00106.25 EIM90150.1 - 2.1e-19 69.8 0.0 3.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90150.1 - 2.4e-11 43.6 0.0 6e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM90150.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM90150.1 - 0.0037 16.7 0.1 0.0074 15.7 0.1 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_hydro_31 PF01055.26 EIM90150.1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Ten1 PF12658.7 EIM90150.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 Telomere capping, CST complex subunit DEAD PF00270.29 EIM90151.1 - 9.2e-48 162.3 0.0 1e-45 155.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM90151.1 - 8.5e-28 96.9 0.0 3.7e-27 94.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM90151.1 - 0.00045 20.3 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 EIM90151.1 - 0.08 12.3 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD SPX PF03105.19 EIM90151.1 - 1.3 8.9 6.4 0.53 10.1 3.4 1.8 2 0 0 2 2 2 0 SPX domain Methyltransf_16 PF10294.9 EIM90153.1 - 5e-17 62.2 0.0 1.8e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EIM90153.1 - 9.6e-06 25.5 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SAM_MT PF04445.13 EIM90153.1 - 0.21 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase RhoGEF PF00621.20 EIM90154.1 - 4.1e-16 59.8 0.0 2e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain TRADD_N PF09034.10 EIM90154.1 - 0.14 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 TRADD, N-terminal domain Asn_synthase PF00733.21 EIM90155.1 - 4.1e-96 322.7 0.0 4.3e-58 197.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EIM90155.1 - 1.2e-35 122.0 0.0 2.1e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EIM90155.1 - 2.3e-29 102.3 0.0 5.9e-29 101.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain QueC PF06508.13 EIM90155.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 EIM90155.1 - 0.049 12.7 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Aldo_ket_red PF00248.21 EIM90156.1 - 9.1e-46 156.4 0.0 1.7e-45 155.4 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family OTT_1508_deam PF14441.6 EIM90157.1 - 5.5e-11 42.3 3.9 8.2e-11 41.8 2.7 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase SopA PF13981.6 EIM90157.1 - 0.019 15.4 0.2 0.18 12.2 0.0 2.5 2 0 0 2 2 2 0 SopA-like central domain Ribosomal_L32p PF01783.23 EIM90157.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.1 3 0 0 3 3 3 0 Ribosomal L32p protein family DUF5602 PF18197.1 EIM90157.1 - 0.23 12.0 1.0 4.6 7.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5602) Syntaxin PF00804.25 EIM90158.1 - 4.9e-29 101.4 7.5 8e-29 100.7 7.5 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EIM90158.1 - 2e-10 40.5 0.5 6.2e-10 38.9 0.5 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EIM90158.1 - 1.7e-07 31.5 3.4 1.7e-07 31.5 3.4 2.2 2 0 0 2 2 2 1 Syntaxin-like protein DUF5098 PF17023.5 EIM90158.1 - 0.062 12.3 2.3 1.2 8.1 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5098) Synaptobrevin PF00957.21 EIM90158.1 - 0.08 12.7 7.6 0.22 11.4 0.6 2.5 2 0 0 2 2 2 0 Synaptobrevin ISG65-75 PF11727.8 EIM90158.1 - 0.13 11.5 1.6 8.7 5.5 1.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF3016 PF11454.8 EIM90158.1 - 0.13 12.0 2.0 2.1 8.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3016) DUF4231 PF14015.6 EIM90158.1 - 0.13 12.7 1.4 8.8 6.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DASH_Dam1 PF08653.10 EIM90158.1 - 0.23 11.3 0.6 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 Allexi_40kDa PF05549.11 EIM90158.1 - 0.25 10.8 3.5 0.27 10.7 0.4 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein LOH1CR12 PF10158.9 EIM90158.1 - 0.26 11.3 5.2 1 9.4 0.1 2.7 3 0 0 3 3 3 0 Tumour suppressor protein BatA PF07584.11 EIM90158.1 - 0.34 11.3 0.7 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal PIN_8 PF18476.1 EIM90158.1 - 0.5 10.2 6.0 7 6.4 1.6 2.2 1 1 1 2 2 2 0 PIN like domain FUSC PF04632.12 EIM90158.1 - 0.54 8.7 11.2 0.022 13.3 3.5 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family SlyX PF04102.12 EIM90158.1 - 1.1 9.9 10.8 0.25 12.0 1.4 3.3 2 1 0 2 2 2 0 SlyX DUF1664 PF07889.12 EIM90158.1 - 1.2 9.1 4.1 15 5.7 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 EIM90158.1 - 1.4 6.7 8.0 0.63 7.9 2.9 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Sec34 PF04136.15 EIM90158.1 - 2.5 8.0 6.5 2.4 8.0 0.1 3.0 3 1 0 3 3 3 0 Sec34-like family DUF16 PF01519.16 EIM90158.1 - 2.6 8.6 5.9 0.6 10.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 Hrs_helical PF12210.8 EIM90158.1 - 9.1 6.9 9.6 9.9 6.8 0.5 3.3 2 2 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CDP-OH_P_transf PF01066.21 EIM90159.1 - 9.3e-13 48.7 0.5 9.3e-13 48.7 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ICL PF00463.21 EIM90160.1 - 8.8e-186 618.5 0.0 1e-185 618.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PapA_C PF16911.5 EIM90160.1 - 0.078 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus DNA_methylase PF00145.17 EIM90161.1 - 1e-38 133.5 0.0 7.6e-37 127.4 0.0 3.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 EIM90161.1 - 2.2e-12 47.3 0.0 3.8e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 EIM90161.1 - 0.00057 19.7 0.0 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 BAH domain Cons_hypoth95 PF03602.15 EIM90161.1 - 0.0022 17.7 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EIM90161.1 - 0.0037 17.0 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein AAA PF00004.29 EIM90162.1 - 1e-35 123.0 0.0 2.2e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM90162.1 - 5.8e-11 42.0 0.0 1.8e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIM90162.1 - 5.2e-07 30.2 1.9 0.008 16.6 0.1 4.8 3 1 1 5 5 5 1 AAA ATPase domain AAA_5 PF07728.14 EIM90162.1 - 0.00073 19.5 0.0 0.0033 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIM90162.1 - 0.0016 18.8 0.1 0.054 13.8 0.0 3.0 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EIM90162.1 - 0.005 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EIM90162.1 - 0.0079 16.4 0.0 0.04 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIM90162.1 - 0.014 16.0 1.6 0.045 14.3 0.0 2.7 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 EIM90162.1 - 0.015 15.0 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 EIM90162.1 - 0.016 15.5 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EIM90162.1 - 0.032 14.3 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EIM90162.1 - 0.041 13.6 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EIM90162.1 - 0.046 12.7 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TniB PF05621.11 EIM90162.1 - 0.058 12.8 0.0 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 EIM90162.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EIM90162.1 - 0.13 11.7 0.3 0.3 10.4 0.3 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EIM90162.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 EIM90162.1 - 0.17 11.6 1.8 0.51 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 EIM90162.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain CDP-OH_P_transf PF01066.21 EIM90163.1 - 6.4e-12 46.1 0.4 2.8e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PAP2 PF01569.21 EIM90164.1 - 7.8e-13 48.4 1.9 7.8e-13 48.4 1.9 2.8 3 0 0 3 3 3 1 PAP2 superfamily HEAT PF02985.22 EIM90167.1 - 5.1e-11 41.9 17.5 0.00021 21.3 0.1 7.4 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 EIM90167.1 - 2.6e-07 30.9 15.3 0.00065 20.0 0.0 5.9 4 2 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 EIM90167.1 - 0.0064 17.0 5.2 4.2 8.0 0.2 5.0 2 2 1 3 3 3 3 HEAT-like repeat Cnd1 PF12717.7 EIM90167.1 - 0.077 13.0 0.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Aminotran_1_2 PF00155.21 EIM90168.1 - 3.3e-82 276.6 0.0 3.7e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-AN1 PF01428.16 EIM90169.1 - 6.1e-10 39.1 6.8 6.1e-10 39.1 6.8 1.7 1 1 0 1 1 1 1 AN1-like Zinc finger DUF35_N PF12172.8 EIM90169.1 - 0.9 9.5 8.3 2.8 7.9 0.7 2.3 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Syntaxin PF00804.25 EIM90170.1 - 2.2e-32 112.4 11.4 3e-32 111.9 11.4 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EIM90170.1 - 3.5e-08 33.3 0.6 8.8e-08 32.0 0.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EIM90170.1 - 0.00022 21.6 13.6 0.00022 21.5 9.1 2.2 2 0 0 2 2 2 1 Syntaxin-like protein VitD-bind_III PF09164.10 EIM90170.1 - 0.02 14.9 0.2 0.045 13.7 0.2 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Spectrin PF00435.21 EIM90170.1 - 0.059 13.9 5.0 0.51 10.9 0.1 2.9 3 0 0 3 3 3 0 Spectrin repeat NAP PF00956.18 EIM90170.1 - 0.13 11.4 3.3 0.23 10.6 3.3 1.4 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Mod_r PF07200.13 EIM90170.1 - 0.19 11.9 11.9 0.4 10.8 1.1 3.1 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Tweety PF04906.13 EIM90170.1 - 0.2 10.3 3.2 0.75 8.4 0.2 2.2 2 0 0 2 2 2 0 Tweety WXG100 PF06013.12 EIM90170.1 - 0.38 11.0 0.1 0.38 11.0 0.1 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG ALMT PF11744.8 EIM90170.1 - 0.43 9.3 6.2 0.72 8.6 6.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4743 PF15916.5 EIM90170.1 - 0.49 10.4 3.1 0.73 9.8 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4743) DUF4988 PF16378.5 EIM90170.1 - 0.53 9.9 4.3 1.8 8.2 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function Lyase_1 PF00206.20 EIM90171.1 - 2.1e-96 323.0 0.0 2.7e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EIM90171.1 - 2.4e-24 85.8 0.1 5.9e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Phage_term_smal PF05944.12 EIM90171.1 - 0.048 13.6 0.1 0.95 9.4 0.0 2.3 2 1 0 2 2 2 0 Phage small terminase subunit Peptidase_M24 PF00557.24 EIM90172.1 - 3.5e-42 144.5 0.0 4.5e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EIM90172.1 - 0.004 17.8 0.0 0.0066 17.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain 2OG-FeII_Oxy_2 PF13532.6 EIM90173.1 - 1.5e-23 84.0 0.0 1.8e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M13_N PF05649.13 EIM90174.1 - 1.3e-100 337.8 0.0 1.7e-100 337.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EIM90174.1 - 5.8e-57 192.6 0.3 1.2e-56 191.6 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M13 SSP160 PF06933.11 EIM90174.1 - 2.4 6.3 11.5 3.3 5.8 11.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-Mss51 PF13824.6 EIM90175.1 - 8.3e-25 86.7 11.2 1.4e-24 85.9 11.2 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 EIM90175.1 - 0.32 11.4 7.3 0.57 10.6 6.7 1.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar CDC45 PF02724.14 EIM90176.1 - 1.3e-207 691.0 0.0 1.6e-207 690.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF1707 PF08044.11 EIM90176.1 - 0.032 14.3 0.6 0.12 12.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) Scramblase PF03803.15 EIM90177.1 - 2.4e-56 190.5 0.0 8.4e-56 188.7 0.0 1.7 1 1 0 1 1 1 1 Scramblase GTP_EFTU PF00009.27 EIM90178.1 - 3.5e-32 111.5 3.1 3.5e-32 111.5 3.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EIM90178.1 - 2.4e-25 88.7 0.2 5.7e-25 87.5 0.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EIM90178.1 - 3.5e-08 33.5 0.1 8e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EIM90178.1 - 4.6e-05 23.2 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 EIM90178.1 - 0.00065 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EIM90178.1 - 0.0056 16.9 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EIM90178.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 EIM90178.1 - 0.014 15.8 1.6 0.34 11.3 0.2 3.2 2 1 0 2 2 2 0 Elongation factor Tu domain 2 MeaB PF03308.16 EIM90178.1 - 0.023 13.7 3.9 0.05 12.6 3.8 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 EIM90178.1 - 0.28 10.9 0.5 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Phosphoesterase PF04185.14 EIM90179.1 - 6.1e-30 104.6 3.0 1.9e-29 103.0 3.0 1.7 1 1 0 1 1 1 1 Phosphoesterase family Mito_carr PF00153.27 EIM90180.1 - 1.7e-07 31.1 0.1 0.049 13.6 0.2 3.6 3 1 0 3 3 3 2 Mitochondrial carrier protein CxC5 PF18718.1 EIM90181.1 - 3.1e-38 130.5 6.4 4.6e-38 129.9 5.7 1.7 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EIM90181.1 - 1.3e-22 79.9 3.6 1.3e-22 79.9 3.6 2.5 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases CPT PF07931.12 EIM90182.1 - 0.056 13.3 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein 2OG-FeII_Oxy_2 PF13532.6 EIM90184.1 - 6.7e-10 39.5 0.0 1.1e-09 38.8 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 EIM90185.1 - 0.00036 20.0 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90185.1 - 0.013 15.1 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase VCBS PF13517.6 EIM90186.1 - 0.053 14.1 0.8 0.067 13.8 0.8 1.1 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PTCRA PF15028.6 EIM90186.1 - 0.087 12.5 0.1 0.089 12.5 0.1 1.1 1 0 0 1 1 1 0 Pre-T-cell antigen receptor WD40 PF00400.32 EIM90187.1 - 7.6e-40 134.2 17.0 1.7e-11 44.5 0.8 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90187.1 - 1.5e-13 50.9 2.6 0.00058 20.1 0.0 5.2 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM90187.1 - 1.2e-08 34.4 2.5 0.17 10.8 0.0 4.7 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EIM90187.1 - 4.7e-06 25.5 1.9 0.44 9.1 0.1 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.11 EIM90187.1 - 6.6e-06 26.0 0.6 0.012 15.3 0.1 2.5 1 1 1 2 2 2 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EIM90187.1 - 0.00025 19.9 1.5 0.12 11.1 0.1 4.1 1 1 2 3 3 3 1 Nup133 N terminal like PALB2_WD40 PF16756.5 EIM90187.1 - 0.015 14.3 2.5 0.016 14.2 0.1 2.2 3 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EIM90187.1 - 0.016 13.5 0.0 0.028 12.8 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PAN_3 PF08277.12 EIM90187.1 - 0.018 14.8 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 PAN-like domain HPS3_N PF14761.6 EIM90187.1 - 0.022 14.3 0.1 0.33 10.4 0.0 2.7 1 1 2 3 3 3 0 Hermansky-Pudlak syndrome 3 WD40_3 PF15911.5 EIM90187.1 - 0.026 14.5 0.0 0.28 11.2 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat GATase_2 PF00310.21 EIM90188.1 - 1.4e-177 590.6 0.0 1.9e-177 590.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EIM90188.1 - 1.2e-154 514.9 0.0 2e-154 514.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EIM90188.1 - 7.1e-112 373.4 0.0 1.8e-110 368.8 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EIM90188.1 - 5.2e-87 290.4 4.5 8.5e-87 289.7 4.5 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EIM90188.1 - 4.9e-25 88.4 0.0 3.1e-24 85.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EIM90188.1 - 5.1e-22 77.8 0.1 9.9e-22 76.8 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 EIM90188.1 - 6.8e-10 39.4 0.0 5.3e-06 26.9 0.0 4.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM90188.1 - 2.2e-09 37.0 0.0 0.00014 21.2 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM90188.1 - 2.4e-09 37.3 0.0 1e-08 35.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM90188.1 - 6.5e-08 32.5 0.1 0.0042 16.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM90188.1 - 1.3e-05 24.1 0.6 2.9e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EIM90188.1 - 3.5e-05 23.3 0.0 6.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EIM90188.1 - 0.00099 18.4 1.0 0.0018 17.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EIM90188.1 - 0.0013 19.1 0.8 0.22 12.0 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 EIM90188.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FMN_dh PF01070.18 EIM90188.1 - 0.002 17.2 1.3 0.011 14.8 0.9 2.3 3 0 0 3 3 3 1 FMN-dependent dehydrogenase FAD_binding_2 PF00890.24 EIM90188.1 - 0.0029 16.8 0.0 0.0029 16.8 0.0 2.6 3 0 0 3 3 2 1 FAD binding domain FAD_binding_3 PF01494.19 EIM90188.1 - 0.0038 16.5 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 EIM90188.1 - 0.016 13.6 0.1 0.51 8.7 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 EIM90188.1 - 0.031 13.7 0.0 0.093 12.1 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.24 EIM90188.1 - 0.034 13.9 0.7 0.49 10.2 0.1 3.0 3 1 1 4 4 4 0 DJ-1/PfpI family NAD_binding_9 PF13454.6 EIM90188.1 - 0.036 14.1 0.0 0.14 12.1 0.0 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EIM90188.1 - 0.054 12.8 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 EIM90188.1 - 0.066 13.3 2.4 7.5 6.6 0.3 3.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 EIM90188.1 - 0.092 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EIM90188.1 - 0.1 12.5 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EIM90188.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 EIM90188.1 - 0.39 9.7 1.4 1.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Acetyltransf_13 PF13880.6 EIM90189.1 - 6.6e-17 61.2 0.0 1.6e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EIM90189.1 - 4e-09 36.1 0.7 7.2e-09 35.3 0.7 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 EIM90189.1 - 0.0013 19.1 0.0 0.025 15.0 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM90189.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM90189.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 EIM90190.1 - 1.8e-19 69.9 24.7 1.8e-19 69.9 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EIM90190.1 - 2.2e-08 33.9 3.3 6e-08 32.5 3.3 1.7 1 0 0 1 1 1 1 Nodulin-like NADH-u_ox-rdase PF10785.9 EIM90190.1 - 0.32 11.7 2.7 3.3 8.5 0.2 3.2 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Far-17a_AIG1 PF04750.14 EIM90191.1 - 7.4e-33 113.6 5.0 9e-33 113.3 5.0 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Foie-gras_1 PF11817.8 EIM90191.1 - 0.21 11.1 0.2 0.38 10.3 0.0 1.5 2 0 0 2 2 2 0 Foie gras liver health family 1 MFS_1 PF07690.16 EIM90192.1 - 5.5e-25 88.0 29.7 5.5e-25 88.0 29.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 EIM90194.1 - 2.6e-78 263.5 0.0 3.4e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM90194.1 - 0.0003 21.7 0.0 0.00065 20.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_1 PF00036.32 EIM90195.1 - 4.8e-22 75.8 2.4 2.6e-05 23.4 0.1 4.8 4 2 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EIM90195.1 - 5.9e-22 75.7 2.3 3.5e-06 26.5 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EIM90195.1 - 6.1e-19 68.2 0.1 3.6e-08 33.7 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EIM90195.1 - 3.3e-16 57.9 0.2 0.00022 20.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EIM90195.1 - 1.5e-15 56.7 5.2 6.9e-09 35.4 0.2 4.6 3 3 1 4 4 4 4 EF-hand domain pair Caleosin PF05042.13 EIM90195.1 - 0.054 13.4 0.0 0.3 11.0 0.0 2.2 1 1 1 2 2 2 0 Caleosin related protein HAD_2 PF13419.6 EIM90196.1 - 9.4e-08 32.3 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM90196.1 - 0.0058 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 EIM90196.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase AP_endonuc_2 PF01261.24 EIM90196.1 - 0.17 11.3 0.0 0.45 9.9 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel QCR10 PF09796.9 EIM90197.1 - 7.2e-23 80.4 0.2 8.4e-23 80.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Nop16 PF09420.10 EIM90198.1 - 4.3e-50 170.7 3.3 4.9e-50 170.5 3.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 FAM177 PF14774.6 EIM90198.1 - 0.056 13.8 0.8 0.094 13.1 0.8 1.3 1 0 0 1 1 1 0 FAM177 family Ribosomal_L36e PF01158.18 EIM90198.1 - 0.28 11.5 0.0 0.28 11.5 0.0 1.9 3 0 0 3 3 3 0 Ribosomal protein L36e Zn_clus PF00172.18 EIM90199.1 - 0.024 14.7 7.0 0.047 13.8 7.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zinc_ribbon_15 PF17032.5 EIM90200.1 - 9.8e-07 29.4 0.3 1.4e-06 28.9 0.3 1.2 1 0 0 1 1 1 1 zinc-ribbon family DUF3716 PF12511.8 EIM90200.1 - 0.01 15.9 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Zn_Tnp_IS1595 PF12760.7 EIM90200.1 - 0.056 13.4 3.8 0.19 11.7 3.8 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain FYVE_2 PF02318.16 EIM90200.1 - 0.22 11.8 4.1 6 7.1 0.2 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger RecR PF02132.15 EIM90200.1 - 1.5 8.4 4.8 19 4.9 4.8 2.1 1 1 0 1 1 1 0 RecR protein Nudix_N_2 PF14803.6 EIM90200.1 - 6.9 6.7 7.6 0.68 9.9 1.8 2.1 2 0 0 2 2 2 0 Nudix N-terminal Ras PF00071.22 EIM90201.1 - 3.1e-65 218.7 1.3 4e-65 218.4 1.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM90201.1 - 1.9e-36 124.9 1.0 2.2e-36 124.7 0.1 1.5 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM90201.1 - 3.2e-17 62.5 0.3 4e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EIM90201.1 - 7.5e-09 35.7 1.6 7.9e-05 22.6 0.5 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EIM90201.1 - 3.8e-06 26.6 0.5 1.1e-05 25.1 0.5 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EIM90201.1 - 1.1e-05 25.0 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIM90201.1 - 1.1e-05 24.9 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EIM90201.1 - 4.9e-05 23.4 0.1 4.9e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM90201.1 - 0.00073 20.0 0.3 0.011 16.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EIM90201.1 - 0.0034 16.9 1.0 0.18 11.3 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 EIM90201.1 - 0.0045 17.4 1.5 0.52 10.7 0.0 3.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EIM90201.1 - 0.0054 16.4 0.9 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain FeoB_N PF02421.18 EIM90201.1 - 0.0098 15.4 0.1 0.049 13.2 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EIM90201.1 - 0.017 15.4 1.5 0.11 12.8 0.0 2.5 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EIM90201.1 - 0.035 14.6 0.5 0.21 12.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 EIM90201.1 - 0.037 14.0 0.5 0.085 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 EIM90201.1 - 0.067 12.5 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin TniB PF05621.11 EIM90201.1 - 0.068 12.6 0.0 0.27 10.6 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 EIM90201.1 - 0.23 11.9 2.4 1.5 9.3 0.2 2.8 2 1 0 2 2 2 0 RNA helicase Asp PF00026.23 EIM90202.1 - 4.3e-42 144.6 2.7 5.7e-42 144.2 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM90202.1 - 6.3e-08 33.1 2.2 4.5e-06 27.0 2.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM90202.1 - 0.031 14.9 0.8 0.45 11.2 0.2 2.6 2 1 0 2 2 2 0 Aspartyl protease LapA_dom PF06305.11 EIM90202.1 - 6.3 6.7 6.6 7.9 6.4 3.5 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Piwi PF02171.17 EIM90203.1 - 1.7e-76 257.3 0.0 2.3e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 EIM90203.1 - 3.8e-06 27.2 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EIM90203.1 - 0.013 15.7 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute WD40 PF00400.32 EIM90204.1 - 1.5e-15 57.3 13.9 2.9e-08 34.2 0.4 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90204.1 - 0.00015 22.0 0.1 0.11 12.9 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EIM90204.1 - 0.05 12.4 0.0 4.7 5.8 0.1 2.7 2 1 0 2 2 2 0 Nup133 N terminal like DUF3592 PF12158.8 EIM90204.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) NMO PF03060.15 EIM90205.1 - 8.9e-53 179.8 0.5 1.3e-52 179.2 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EIM90205.1 - 2.3e-09 36.7 0.1 6e-08 32.1 0.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EIM90205.1 - 0.0018 17.4 2.0 0.003 16.6 2.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyto_heme_lyase PF01265.17 EIM90206.1 - 1.5e-48 165.9 3.5 3.1e-47 161.6 3.5 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Brix PF04427.18 EIM90207.1 - 1.1e-43 149.6 0.0 1.5e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain PPL5 PF18168.1 EIM90207.1 - 0.055 12.8 3.5 0.087 12.1 3.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 TFIIA PF03153.13 EIM90207.1 - 0.24 11.3 17.2 0.33 10.9 17.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.9 EIM90207.1 - 0.54 10.7 24.5 1.1 9.7 24.5 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Paf1 PF03985.13 EIM90207.1 - 1.4 7.8 17.3 2 7.3 17.3 1.2 1 0 0 1 1 1 0 Paf1 PSK_trans_fac PF07704.11 EIM90207.1 - 2.4 9.0 9.1 1.5 9.7 6.4 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor Pkinase PF00069.25 EIM90209.1 - 2.6e-65 220.4 0.0 3.2e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90209.1 - 7.4e-30 104.1 0.0 9.5e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM90209.1 - 0.00063 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cytochrom_B561 PF03188.16 EIM90210.1 - 6.9e-10 39.2 11.3 7.2e-10 39.1 8.2 2.3 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 DUF202 PF02656.15 EIM90210.1 - 4.6 7.8 18.5 0.4 11.1 0.3 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF202) Sec7 PF01369.20 EIM90211.1 - 3.6e-66 222.3 0.1 6e-66 221.6 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EIM90211.1 - 8.8e-19 68.0 1.1 1.6e-17 63.9 0.0 3.0 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EIM90211.1 - 0.0095 15.8 2.7 3.4 7.6 0.1 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF2232 PF09991.9 EIM90211.1 - 0.094 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Proteasome PF00227.26 EIM90212.1 - 6.9e-60 201.8 0.1 9.4e-60 201.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIM90212.1 - 2.4e-14 52.7 0.3 1.1e-13 50.6 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MAT1 PF06391.13 EIM90213.1 - 4.7e-51 173.5 13.6 5.7e-51 173.3 13.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EIM90213.1 - 8.1e-19 67.2 8.1 1.3e-18 66.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) cIII PF08134.11 EIM90213.1 - 0.018 14.8 0.1 0.05 13.4 0.1 1.8 1 0 0 1 1 1 0 cIII protein family zf-RING_5 PF14634.6 EIM90213.1 - 0.019 14.9 10.1 0.093 12.7 10.5 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM90213.1 - 0.057 13.3 10.9 0.19 11.7 11.0 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM90213.1 - 0.15 12.4 8.1 0.3 11.4 8.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-ribbon_3 PF13248.6 EIM90213.1 - 0.21 11.0 3.4 2.2 7.8 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Med27 PF11571.8 EIM90213.1 - 0.95 9.9 0.0 0.95 9.9 0.0 2.6 3 0 0 3 3 3 0 Mediator complex subunit 27 zf-C3HC4_2 PF13923.6 EIM90213.1 - 1.2 9.1 13.8 7.2 6.5 13.9 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 EIM90213.1 - 1.7 8.8 6.8 14 5.9 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DUF3797 PF12677.7 EIM90213.1 - 4.4 7.3 7.8 0.34 10.8 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-RING_4 PF14570.6 EIM90213.1 - 5.6 6.8 10.4 9.8 6.1 4.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UPF0242 PF06785.11 EIM90213.1 - 5.9 6.9 12.0 4.6 7.3 10.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LigB PF02900.18 EIM90214.1 - 6.7e-38 130.3 0.0 8.6e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Epimerase PF01370.21 EIM90215.1 - 2.6e-05 23.8 0.0 7.2e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EIM90216.1 - 1.5e-32 113.0 0.0 2.3e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EIM90216.1 - 1.6e-25 89.7 0.0 2.6e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SRP-alpha_N PF04086.13 EIM90217.1 - 4e-53 181.2 1.0 1.6e-52 179.3 1.0 1.8 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EIM90217.1 - 2.3e-44 151.4 0.1 2e-43 148.3 0.1 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EIM90217.1 - 2.3e-10 40.6 0.0 6.4e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EIM90217.1 - 2.8e-05 23.2 0.1 6.9e-05 21.9 0.1 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EIM90217.1 - 0.0057 16.4 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EIM90217.1 - 0.019 15.0 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EIM90217.1 - 0.034 13.9 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 EIM90217.1 - 0.039 13.4 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 EIM90217.1 - 0.044 13.7 0.2 0.19 11.6 0.1 2.1 2 1 0 2 2 2 0 NTPase RHH_1 PF01402.21 EIM90217.1 - 0.075 13.0 0.3 7.4 6.7 0.3 3.2 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family ArsA_ATPase PF02374.15 EIM90217.1 - 0.1 11.7 0.1 1.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase Cyclin_N PF00134.23 EIM90218.1 - 6e-09 35.7 0.0 1.7e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EIM90218.1 - 0.02 15.3 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain RAP PF08373.10 EIM90218.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 RAP domain SOR_SNZ PF01680.17 EIM90220.1 - 2.4e-111 370.5 4.6 3.3e-111 370.0 4.6 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EIM90220.1 - 2.8e-11 43.2 2.7 1.3e-07 31.3 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EIM90220.1 - 4.9e-05 22.6 0.4 0.072 12.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 EIM90220.1 - 0.00097 18.4 0.3 0.099 11.8 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 EIM90220.1 - 0.0035 16.8 4.1 0.074 12.4 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase TetR_C_27 PF17935.1 EIM90220.1 - 0.0057 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 EIM90220.1 - 0.0086 15.6 0.6 0.5 9.8 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.18 EIM90220.1 - 0.033 13.2 0.4 0.088 11.8 0.0 1.9 2 1 1 3 3 3 0 FMN-dependent dehydrogenase IGPS PF00218.21 EIM90220.1 - 0.038 13.2 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Img2 PF05046.14 EIM90221.1 - 3.3e-19 69.0 0.0 4.1e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) BTB PF00651.31 EIM90223.1 - 0.0034 17.6 0.0 0.0068 16.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DHO_dh PF01180.21 EIM90224.1 - 1e-89 300.7 0.0 1.4e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 EIM90224.1 - 0.0085 15.5 0.1 0.023 14.1 0.2 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EIM90224.1 - 0.023 13.7 0.7 0.074 12.1 0.7 1.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Aldo_ket_red PF00248.21 EIM90225.1 - 7.6e-42 143.5 0.2 8.6e-41 140.0 0.2 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Dickkopf_N PF04706.12 EIM90226.1 - 0.00085 19.8 5.6 0.00098 19.6 5.6 1.1 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Conotoxin_I2 PF17557.2 EIM90226.1 - 0.0031 17.6 7.6 0.0038 17.3 7.6 1.1 1 0 0 1 1 1 1 I2-superfamily conotoxins Toxin_23 PF08093.11 EIM90226.1 - 0.0084 16.2 8.0 0.011 15.8 8.0 1.3 1 0 0 1 1 1 1 Magi 5 toxic peptide family Conotoxin PF02950.17 EIM90226.1 - 0.013 16.5 7.6 0.013 16.5 7.6 1.7 1 1 1 2 2 2 0 Conotoxin UPF0506 PF11703.8 EIM90226.1 - 0.021 15.2 5.9 0.024 15.0 5.9 1.1 1 0 0 1 1 1 0 UPF0506 Toxin_19 PF08088.12 EIM90226.1 - 0.044 13.9 6.8 0.053 13.7 6.8 1.1 1 0 0 1 1 1 0 Conotoxin I-superfamily Toxin_12 PF07740.12 EIM90226.1 - 0.044 14.5 5.1 0.069 13.9 5.1 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Transferase PF02458.15 EIM90227.1 - 2.4e-32 112.1 0.0 1.6e-18 66.6 0.1 2.9 2 1 0 2 2 2 2 Transferase family Condensation PF00668.20 EIM90227.1 - 0.049 12.3 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Peptidase_C78 PF07910.13 EIM90228.1 - 1.2e-48 165.4 0.0 2e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 CobW_C PF07683.14 EIM90229.1 - 0.024 14.6 0.2 0.076 13.0 0.0 1.8 1 1 1 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain HSBP1 PF06825.12 EIM90229.1 - 0.077 12.9 0.3 0.22 11.4 0.3 1.8 1 1 0 1 1 1 0 Heat shock factor binding protein 1 TMF_DNA_bd PF12329.8 EIM90229.1 - 0.18 11.8 0.1 6 6.9 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HAGH_C PF16123.5 EIM90231.1 - 4.9e-22 78.2 0.2 1e-21 77.2 0.1 1.6 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EIM90231.1 - 1.3e-09 38.3 2.5 3.6e-09 36.9 2.5 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIM90231.1 - 0.00019 21.0 0.2 0.00046 19.8 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Got1 PF04178.12 EIM90232.1 - 1.2e-30 106.3 22.0 1.2e-30 106.3 22.0 1.6 1 1 1 2 2 2 2 Got1/Sft2-like family Ge1_WD40 PF16529.5 EIM90233.1 - 0.073 12.0 0.0 0.21 10.5 0.0 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3629 PF12302.8 EIM90233.1 - 0.22 10.9 1.9 0.45 9.9 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) PPTA PF01239.22 EIM90234.1 - 1.3e-49 164.5 12.3 1.5e-09 37.3 0.0 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF5338 PF17273.2 EIM90234.1 - 0.11 12.6 1.5 0.46 10.6 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5338) DUF3950 PF13132.6 EIM90234.1 - 0.61 9.9 2.9 19 5.1 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) TPR_14 PF13428.6 EIM90235.1 - 1.6e-10 40.9 22.3 2.3 9.3 0.1 12.6 9 3 4 13 13 13 2 Tetratricopeptide repeat Suf PF05843.14 EIM90235.1 - 2.3e-05 24.6 7.4 0.0053 16.8 0.7 4.9 3 1 2 5 5 5 1 Suppressor of forked protein (Suf) TPR_12 PF13424.6 EIM90235.1 - 0.00014 22.0 3.6 3.9 7.8 0.0 5.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM90235.1 - 0.00021 21.2 16.7 0.12 12.6 0.3 7.5 9 0 0 9 9 9 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EIM90235.1 - 0.00034 20.6 11.9 0.83 9.7 0.4 6.3 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 EIM90235.1 - 0.00059 19.8 10.0 7.4 7.1 0.1 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EIM90235.1 - 0.0012 18.0 6.9 0.064 12.4 0.0 4.9 3 2 2 5 5 5 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 EIM90235.1 - 0.07 13.8 6.3 5.1 7.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EIM90235.1 - 0.15 12.1 4.5 1 9.5 0.1 4.3 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain HAT PF02184.16 EIM90235.1 - 0.27 11.2 7.4 3.4 7.7 0.0 5.7 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat DALR_1 PF05746.15 EIM90235.1 - 0.3 11.3 2.0 2.1 8.6 0.0 3.0 3 0 0 3 3 3 0 DALR anticodon binding domain TPR_1 PF00515.28 EIM90235.1 - 0.52 10.2 1.9 63 3.6 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L30_N PF08079.12 EIM90236.1 - 5.1e-27 93.9 16.1 5.1e-27 93.9 16.1 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EIM90236.1 - 8.7e-18 64.0 1.2 8.7e-18 64.0 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 EIM90236.1 - 0.083 12.7 0.6 1.6 8.5 0.0 2.4 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter DFF40 PF09230.10 EIM90236.1 - 0.29 10.7 1.7 0.5 9.9 1.7 1.3 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa tRNA-synt_1b PF00579.25 EIM90238.1 - 3.6e-19 69.2 0.0 1.2e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) V_ATPase_I PF01496.19 EIM90239.1 - 0 1079.6 0.0 0 1079.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Vpu PF00558.19 EIM90239.1 - 4.8 7.0 6.7 1 9.2 0.1 2.9 2 0 0 2 2 2 0 Vpu protein ABC_tran PF00005.27 EIM90240.1 - 3.4e-43 147.4 0.0 1e-20 74.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EIM90240.1 - 5.1e-18 65.9 0.5 0.003 17.4 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIM90240.1 - 1.8e-12 47.2 0.7 0.0075 15.7 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIM90240.1 - 1e-07 31.6 0.2 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EIM90240.1 - 2.9e-07 31.2 6.6 0.0068 16.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EIM90240.1 - 2.5e-06 28.0 0.1 0.0066 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain HEAT_2 PF13646.6 EIM90240.1 - 2.6e-06 27.7 8.1 0.018 15.4 0.0 3.5 2 1 2 4 4 3 2 HEAT repeats AAA_22 PF13401.6 EIM90240.1 - 7e-06 26.4 0.0 0.25 11.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 EIM90240.1 - 1.2e-05 25.6 0.0 0.0068 16.5 0.0 3.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 EIM90240.1 - 1.3e-05 25.6 0.7 0.025 15.0 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 EIM90240.1 - 1.4e-05 25.2 0.0 0.26 11.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM90240.1 - 4.6e-05 23.4 0.1 0.15 12.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EIM90240.1 - 5.3e-05 23.5 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EIM90240.1 - 0.00017 22.0 0.0 1.9 8.9 0.0 3.8 4 1 1 5 5 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EIM90240.1 - 0.00026 21.4 0.0 0.97 9.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EIM90240.1 - 0.00033 20.8 0.0 1.3 9.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 EIM90240.1 - 0.00058 18.9 0.3 0.28 10.1 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Chromo PF00385.24 EIM90240.1 - 0.0006 19.7 0.5 0.0015 18.4 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 EIM90240.1 - 0.0009 19.2 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 EIM90240.1 - 0.0024 17.7 6.4 0.2 11.4 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 EIM90240.1 - 0.0024 17.6 0.6 4.1 7.1 0.0 3.2 4 0 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 EIM90240.1 - 0.0026 17.7 0.2 6.9 6.5 0.0 3.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EIM90240.1 - 0.0028 17.2 0.4 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EIM90240.1 - 0.0046 16.7 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Vac14_Fab1_bd PF12755.7 EIM90240.1 - 0.0054 17.3 0.1 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EIM90240.1 - 0.0069 15.0 3.7 1.1 7.8 1.0 2.2 1 1 0 2 2 2 2 Adaptin N terminal region DUF815 PF05673.13 EIM90240.1 - 0.0076 15.4 0.2 2.9 7.0 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_13 PF13166.6 EIM90240.1 - 0.0098 14.6 0.0 1.9 7.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EIM90240.1 - 0.012 15.9 0.1 2.1 8.6 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit HEAT PF02985.22 EIM90240.1 - 0.012 15.8 6.0 2.3 8.7 0.0 4.9 5 0 0 5 5 3 0 HEAT repeat HEAT_EZ PF13513.6 EIM90240.1 - 0.012 16.1 6.5 14 6.3 0.1 5.3 5 0 0 5 5 5 0 HEAT-like repeat 4HB PF17947.1 EIM90240.1 - 0.029 14.4 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 Four helical bundle domain Roc PF08477.13 EIM90240.1 - 0.036 14.3 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLASP_N PF12348.8 EIM90240.1 - 0.037 13.6 0.5 9.9 5.6 0.1 2.6 1 1 0 2 2 2 0 CLASP N terminal NB-ARC PF00931.22 EIM90240.1 - 0.051 12.8 0.0 5.4 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 EIM90240.1 - 0.054 12.7 0.1 2 7.5 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 EIM90240.1 - 0.058 13.4 1.6 16 5.5 0.0 3.1 3 1 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 EIM90240.1 - 0.061 13.1 1.6 10 5.8 0.0 3.0 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 EIM90240.1 - 0.098 12.4 0.1 6.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 EIM90240.1 - 0.1 12.2 0.1 10 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EIM90240.1 - 0.1 12.6 5.4 10 6.2 0.1 4.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EIM90240.1 - 0.1 11.8 1.6 0.51 9.5 0.0 2.7 3 0 0 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.15 EIM90240.1 - 0.1 12.5 0.2 12 5.8 0.1 2.8 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 EIM90240.1 - 0.11 12.6 0.2 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.6 EIM90240.1 - 0.13 12.2 0.5 27 4.8 0.5 3.5 3 1 0 3 3 2 0 AAA domain DUF3437 PF11919.8 EIM90240.1 - 0.82 9.6 2.5 2.6 8.0 0.1 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF3437) ATP_bind_1 PF03029.17 EIM90240.1 - 4.5 7.0 5.1 2.9 7.6 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Peptidase_M50B PF13398.6 EIM90241.1 - 4.6e-59 199.4 21.4 6.1e-59 199.0 21.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like F-box-like PF12937.7 EIM90242.1 - 5.4e-05 23.0 6.1 0.00032 20.5 1.9 2.9 2 1 0 2 2 2 2 F-box-like TBP PF00352.21 EIM90243.1 - 4.4e-66 218.8 0.3 2.9e-32 110.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EIM90243.1 - 0.00021 21.3 1.8 0.38 10.9 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EIM90243.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Spt20 PF12090.8 EIM90243.1 - 0.31 10.6 7.1 0.43 10.1 7.1 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 EIM90243.1 - 0.53 10.2 7.7 0.67 9.9 7.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_3 PF01596.17 EIM90245.1 - 1.4e-40 138.7 0.0 1.7e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EIM90245.1 - 3.9e-18 66.4 0.0 1.1e-17 64.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EIM90245.1 - 9.6e-08 32.0 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EIM90245.1 - 2.2e-07 30.8 0.0 4.2e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM90245.1 - 1.6e-06 28.8 0.0 5.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM90245.1 - 3.5e-05 24.4 0.0 0.00013 22.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EIM90245.1 - 0.0037 16.9 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 EIM90245.1 - 0.0065 16.1 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EIM90245.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EIM90245.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_88 PF07470.13 EIM90246.1 - 8.6e-14 51.4 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 BTB PF00651.31 EIM90248.1 - 0.00051 20.2 0.0 0.0009 19.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain FYVE PF01363.21 EIM90250.1 - 2.1e-13 50.2 7.7 4.2e-13 49.2 7.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger SDA1 PF05285.12 EIM90252.1 - 5.2 6.4 27.1 3.4 7.0 12.6 2.2 2 0 0 2 2 2 0 SDA1 MFS_1 PF07690.16 EIM90253.1 - 2.3e-20 72.9 31.0 3.4e-20 72.3 31.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM90253.1 - 0.0014 17.6 1.4 0.0014 17.6 1.4 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter PhzC-PhzF PF02567.16 EIM90254.1 - 3.4e-40 138.3 0.2 6.3e-40 137.4 0.2 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Hat1_N PF10394.9 EIM90255.1 - 5.1e-52 176.3 0.0 8.8e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EIM90255.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 EIM90255.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.7 EIM90255.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rpp20 PF12328.8 EIM90257.1 - 3.1e-07 30.4 0.0 5.8e-06 26.3 0.0 2.0 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EIM90257.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alba eRF1_2 PF03464.15 EIM90258.1 - 6.9e-47 159.1 0.0 1.2e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EIM90258.1 - 1.6e-38 131.7 0.4 3.4e-38 130.6 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EIM90258.1 - 1.9e-19 69.9 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EIM90258.1 - 1.3e-11 44.8 0.1 2.1e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EIM90258.1 - 1e-08 35.6 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 MSA-2c PF12238.8 EIM90259.1 - 4.1 7.3 5.3 4.8 7.1 5.3 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ras PF00071.22 EIM90262.1 - 3.4e-53 179.6 0.0 3.9e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM90262.1 - 2.6e-19 69.6 0.0 3.7e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM90262.1 - 1.6e-07 30.9 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIM90262.1 - 0.034 13.7 0.0 0.22 11.0 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 EIM90262.1 - 0.058 13.7 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Amino_oxidase PF01593.24 EIM90264.1 - 1.6e-63 215.6 0.2 1.4e-47 163.0 0.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIM90264.1 - 4.8e-11 42.7 0.3 1.4e-10 41.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM90264.1 - 1.3e-05 24.6 0.0 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM90264.1 - 0.0002 20.7 0.2 0.00032 20.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EIM90264.1 - 0.00033 19.8 0.1 0.00056 19.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM90264.1 - 0.00082 19.0 1.1 0.005 16.5 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM90264.1 - 0.0014 18.0 0.0 0.0053 16.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EIM90264.1 - 0.0022 17.4 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EIM90264.1 - 0.0025 18.3 1.1 0.015 15.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM90264.1 - 0.0091 15.4 0.5 0.014 14.8 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM90264.1 - 0.038 12.7 0.1 0.067 11.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EIM90264.1 - 0.08 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EIM90264.1 - 0.14 11.2 0.0 11 4.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 EIM90264.1 - 0.23 11.5 0.0 0.42 10.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EIM90264.1 - 0.26 10.3 1.5 0.21 10.6 0.2 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Ribonuclease_3 PF00636.26 EIM90265.1 - 3e-40 137.1 0.0 4.7e-19 69.0 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIM90265.1 - 4.3e-26 91.6 0.1 1.4e-15 57.6 0.0 4.3 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EIM90265.1 - 2.1e-16 59.8 0.0 4.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.15 EIM90265.1 - 2.2e-15 57.1 0.0 4.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM90265.1 - 4.5e-15 56.0 0.1 1.2e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM90265.1 - 3e-13 49.9 0.0 6.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EIM90265.1 - 0.0048 16.6 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase RRM_1 PF00076.22 EIM90267.1 - 1.8e-35 120.6 0.0 3.2e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM90267.1 - 0.019 15.1 0.0 0.057 13.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 EIM90267.1 - 0.19 11.4 0.0 21 4.7 0.0 2.2 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phosducin PF02114.16 EIM90268.1 - 0.0011 17.9 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosducin FAM176 PF14851.6 EIM90268.1 - 0.0054 16.4 0.3 2.3 7.9 0.0 2.2 2 0 0 2 2 2 2 FAM176 family CENP-B_dimeris PF09026.10 EIM90268.1 - 0.21 12.0 10.3 0.17 12.3 0.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WRNPLPNID PF15017.6 EIM90268.1 - 0.34 11.8 7.5 11 6.9 0.0 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Spt5_N PF11942.8 EIM90268.1 - 0.57 11.2 12.0 0.83 10.7 1.0 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 EIM90268.1 - 9.9 6.6 9.4 1.4 9.3 0.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MIF PF01187.18 EIM90269.1 - 1.5e-21 76.8 0.0 1.7e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) zf-C3HC4_2 PF13923.6 EIM90270.1 - 3e-10 39.8 7.1 3e-10 39.8 7.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM90270.1 - 3.4e-09 36.5 6.3 3.4e-09 36.5 6.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIM90270.1 - 4.9e-09 35.9 4.6 4.9e-09 35.9 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIM90270.1 - 3.5e-08 33.2 6.3 3.5e-08 33.2 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM90270.1 - 8.1e-08 32.2 5.2 8.1e-08 32.2 5.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIM90270.1 - 2.6e-07 30.7 8.5 2.6e-07 30.7 8.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EIM90270.1 - 2.4e-06 27.8 6.6 2.4e-06 27.8 6.6 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EIM90270.1 - 7.9e-06 25.6 14.5 1.5e-05 24.8 7.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EIM90270.1 - 1.3e-05 25.0 2.4 1.3e-05 25.0 2.4 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EIM90270.1 - 5.5e-05 23.2 4.2 5.5e-05 23.2 4.2 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 SAP PF02037.27 EIM90270.1 - 7.5e-05 22.4 0.0 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 1 SAP domain zf-RING_4 PF14570.6 EIM90270.1 - 0.001 18.8 2.2 0.001 18.8 2.2 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EIM90270.1 - 0.0035 17.6 4.8 0.0035 17.6 4.8 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 EIM90270.1 - 0.0069 16.5 0.6 0.025 14.8 0.0 2.3 3 0 0 3 3 2 1 U-box domain zf-WRNIP1_ubi PF18279.1 EIM90270.1 - 0.14 12.8 3.8 4.6 8.1 1.8 2.7 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain YacG PF03884.14 EIM90270.1 - 0.22 11.3 4.5 4.2 7.2 0.1 3.3 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG TRAF6_Z2 PF18048.1 EIM90270.1 - 1 9.5 4.7 0.39 10.8 1.2 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 DUF2384 PF09722.10 EIM90271.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) zf-MYND PF01753.18 EIM90273.1 - 7.3e-11 42.0 16.2 1.4e-10 41.1 16.2 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EIM90273.1 - 0.0024 17.7 8.4 0.0038 17.1 8.4 1.3 1 0 0 1 1 1 1 HIT zinc finger Ecl1 PF12855.7 EIM90273.1 - 0.018 16.2 0.3 0.018 16.2 0.3 2.6 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins Tsc35 PF15079.6 EIM90273.1 - 0.02 14.5 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Testis-specific protein 35 zf-Mss51 PF13824.6 EIM90273.1 - 0.2 11.8 6.4 0.58 10.3 6.4 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EIM90273.1 - 0.46 10.8 15.1 0.86 10.0 15.1 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Tom7 PF08038.12 EIM90274.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 TOM7 family DNA_primase_S PF01896.19 EIM90275.1 - 3.6e-55 186.7 0.1 5e-55 186.3 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit Stealth_CR4 PF17103.5 EIM90275.1 - 0.028 14.3 0.3 0.095 12.6 0.3 2.0 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Recombinase PF07508.13 EIM90275.1 - 0.095 13.1 0.9 0.37 11.2 0.0 2.4 3 0 0 3 3 3 0 Recombinase Acetyltransf_2 PF00797.17 EIM90276.1 - 1.6e-23 83.8 0.1 8.4e-22 78.1 0.1 2.6 2 1 0 2 2 2 2 N-acetyltransferase DUF1077 PF06417.12 EIM90277.1 - 3.2e-45 152.9 0.2 3.9e-45 152.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Senescence PF06911.12 EIM90278.1 - 2.8e-30 106.0 17.9 2.9e-29 102.7 17.9 2.2 1 1 0 1 1 1 1 Senescence-associated protein HA2 PF04408.23 EIM90280.1 - 6.7e-14 52.1 0.1 1.7e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIM90280.1 - 5.9e-13 49.1 0.0 1.5e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM90280.1 - 5.9e-07 29.4 0.0 3.1e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EIM90280.1 - 1.5e-05 25.2 0.0 3.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EIM90280.1 - 2.3e-05 24.7 0.0 6.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIM90280.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM90280.1 - 0.0062 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EIM90280.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 EIM90280.1 - 0.044 13.8 0.0 0.94 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EIM90280.1 - 0.052 13.2 0.0 0.68 9.5 0.0 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EIM90280.1 - 0.061 13.8 0.0 0.26 11.8 0.0 1.8 1 1 0 2 2 2 0 ABC transporter FeS_assembly_P PF01883.19 EIM90282.1 - 3.7e-08 33.4 0.0 6.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Cullin_binding PF03556.15 EIM90283.1 - 2.9e-27 95.5 0.5 1.4e-26 93.3 0.2 1.9 2 0 0 2 2 2 1 Cullin binding dsDNA_bind PF01984.20 EIM90284.1 - 9.5e-32 109.6 6.6 1.1e-31 109.4 6.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain zf-RING_4 PF14570.6 EIM90285.1 - 1.4e-21 76.0 12.5 2.4e-21 75.2 12.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EIM90285.1 - 1.6e-06 27.8 8.9 2.9e-06 27.0 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM90285.1 - 0.00043 20.1 9.1 0.028 14.3 10.0 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 EIM90285.1 - 0.00073 19.3 0.0 0.0024 17.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 EIM90285.1 - 0.0072 16.6 12.7 0.013 15.8 12.7 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 EIM90285.1 - 0.035 14.0 3.2 0.08 12.9 3.2 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 EIM90285.1 - 0.046 13.8 3.9 0.11 12.7 3.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 EIM90285.1 - 0.19 11.7 13.2 0.33 10.9 13.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM90285.1 - 0.86 9.7 8.2 1.3 9.1 7.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger 2OG-FeII_Oxy_3 PF13640.6 EIM90286.1 - 8.3e-11 42.6 0.0 1.6e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EIM90286.1 - 0.083 13.6 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cupredoxin_1 PF13473.6 EIM90287.1 - 6.9e-06 26.1 1.2 0.067 13.3 0.1 2.8 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.20 EIM90287.1 - 0.00073 19.9 3.5 0.68 10.4 0.2 3.4 2 2 1 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 EIM90287.1 - 0.0085 16.1 7.1 0.44 10.6 0.7 3.6 2 2 0 2 2 2 2 Plastocyanin-like domain CusF_Ec PF11604.8 EIM90287.1 - 0.048 13.6 0.5 2.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF DUF4501 PF14946.6 EIM90287.1 - 1.3 9.1 10.1 4.6 7.3 3.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4501) G-patch PF01585.23 EIM90288.1 - 6.1e-09 35.6 1.2 1.5e-08 34.4 1.2 1.7 1 0 0 1 1 1 1 G-patch domain zf-MYND PF01753.18 EIM90290.1 - 1.1e-11 44.6 14.3 2.1e-11 43.7 14.3 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM90290.1 - 0.64 10.4 14.4 0.5 10.7 8.0 2.6 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Lysis_col PF02402.16 EIM90290.1 - 2.2 8.0 9.1 0.15 11.7 3.7 2.0 2 0 0 2 2 2 0 Lysis protein F1F0-ATPsyn_F PF10791.9 EIM90292.1 - 5.2e-26 90.9 0.0 6.1e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi SHR3_chaperone PF08229.11 EIM90293.1 - 5.6e-38 129.8 0.0 6.7e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.6 EIM90293.1 - 0.023 15.1 0.2 0.16 12.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) RsfS PF02410.15 EIM90294.1 - 2.6e-05 24.6 0.0 4.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CsbD PF05532.12 EIM90295.1 - 0.00079 19.3 1.6 0.00079 19.3 1.6 1.6 2 0 0 2 2 2 1 CsbD-like LETM1 PF07766.13 EIM90296.1 - 1.1e-102 343.0 0.6 1.1e-102 343.0 0.6 2.1 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 EIM90296.1 - 0.00019 21.8 1.6 0.022 15.2 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair SAP PF02037.27 EIM90296.1 - 0.003 17.3 0.0 0.064 13.0 0.0 3.1 3 0 0 3 3 3 1 SAP domain EF-hand_8 PF13833.6 EIM90296.1 - 0.0042 16.9 0.1 0.085 12.7 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EIM90296.1 - 0.1 12.2 0.4 0.48 10.1 0.0 2.4 3 0 0 3 3 3 0 EF hand Med3 PF11593.8 EIM90296.1 - 0.19 10.9 6.2 0.35 10.0 6.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ALMT PF11744.8 EIM90296.1 - 0.5 9.1 6.4 0.93 8.2 6.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Gpi16 PF04113.14 EIM90297.1 - 3.6e-136 454.9 0.0 3.1e-135 451.8 0.0 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component TF_Zn_Ribbon PF08271.12 EIM90299.1 - 0.009 15.5 0.5 0.02 14.4 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 EIM90299.1 - 0.076 12.7 0.5 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Glycos_transf_1 PF00534.20 EIM90300.1 - 8.3e-21 74.3 0.0 1.7e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIM90300.1 - 1.3e-13 51.6 0.0 2.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EIM90300.1 - 1.4e-05 25.4 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 MutS_V PF00488.21 EIM90301.1 - 9.1e-69 231.3 2.1 1.7e-68 230.3 0.9 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EIM90301.1 - 4.1e-34 118.5 0.2 4.1e-34 118.5 0.2 2.2 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.20 EIM90301.1 - 1.7e-24 86.2 0.1 3.2e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EIM90301.1 - 2.3e-10 40.9 0.0 6.4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EIM90301.1 - 7.2e-06 26.3 0.0 3.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 MutS family domain IV Sporozoite_P67 PF05642.11 EIM90301.1 - 0.45 8.5 4.1 0.78 7.7 4.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATP12 PF07542.11 EIM90302.1 - 4e-43 146.6 0.4 7e-43 145.8 0.4 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein BBIP10 PF14777.6 EIM90302.1 - 0.036 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 MUG113 PF13455.6 EIM90304.1 - 5e-14 52.7 0.0 1.4e-13 51.3 0.0 1.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EIM90304.1 - 2.6e-10 40.8 0.0 5e-09 36.6 0.0 2.6 3 0 0 3 3 3 1 T5orf172 domain Sas10_Utp3 PF04000.15 EIM90305.1 - 1.6e-11 44.6 0.6 3.4e-11 43.6 0.6 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family HTH_5 PF01022.20 EIM90305.1 - 0.014 15.2 0.2 0.029 14.2 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Pox_polyA_pol_N PF12630.7 EIM90305.1 - 0.16 12.4 0.2 0.49 10.8 0.0 1.8 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain UDG PF03167.19 EIM90307.1 - 2.1e-20 73.3 0.1 2.9e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2016 PF09436.10 EIM90307.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) UCH_1 PF13423.6 EIM90308.1 - 2e-81 274.1 0.0 2.8e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EIM90308.1 - 1.4e-18 68.0 0.0 2.6e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EIM90308.1 - 8.7e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 EIM90308.1 - 0.032 14.5 0.0 26 5.2 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM90308.1 - 0.13 13.2 0.3 45 5.1 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ_3 PF13570.6 EIM90308.1 - 0.63 10.6 2.0 10 6.7 0.0 3.9 5 0 0 5 5 5 0 PQQ-like domain FMO-like PF00743.19 EIM90309.1 - 1.3e-44 152.5 0.0 1.2e-32 113.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM90309.1 - 1.5e-17 63.9 0.0 2.7e-14 53.1 0.0 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM90309.1 - 7.6e-11 41.8 0.0 1.8e-10 40.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM90309.1 - 7.7e-10 38.4 0.0 3.3e-08 33.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EIM90309.1 - 3.5e-07 30.4 0.1 7e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM90309.1 - 1.1e-05 25.5 0.0 4.8e-05 23.4 0.0 2.1 2 1 0 2 2 1 1 FAD-NAD(P)-binding DAO PF01266.24 EIM90309.1 - 0.00026 20.7 0.1 9.9 5.6 0.0 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM90309.1 - 0.0074 16.8 0.2 0.4 11.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM90309.1 - 0.0076 15.5 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EIM90309.1 - 0.0096 14.7 0.2 0.16 10.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 EIM90309.1 - 0.025 14.6 0.1 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EIM90309.1 - 0.035 13.4 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 EIM90309.1 - 0.04 13.0 0.1 1.5 7.8 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 EIM90309.1 - 0.13 12.7 0.0 0.69 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EIM90309.1 - 0.22 12.1 0.0 2.6 8.7 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3535 PF12054.8 EIM90310.1 - 2.4e-94 317.0 0.1 5.4e-93 312.6 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EIM90310.1 - 1.1e-71 241.4 0.1 2.1e-71 240.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM90310.1 - 2.7e-17 63.1 0.0 8.9e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 EIM90310.1 - 3.3e-13 48.6 25.0 0.19 12.1 0.0 10.7 11 0 0 11 11 11 5 HEAT repeat Vac14_Fab1_bd PF12755.7 EIM90310.1 - 1.3e-05 25.7 0.0 0.05 14.2 0.1 3.1 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EIM90310.1 - 1.9e-05 24.3 0.0 7.4e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 CLASP N terminal HEAT_EZ PF13513.6 EIM90310.1 - 0.0001 22.7 12.0 7 7.3 0.0 8.0 7 1 1 8 8 8 1 HEAT-like repeat ERCC3_RAD25_C PF16203.5 EIM90310.1 - 0.017 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HEAT_2 PF13646.6 EIM90310.1 - 0.057 13.8 15.9 8.8 6.8 0.0 7.7 9 1 0 9 9 9 0 HEAT repeats Cupin_8 PF13621.6 EIM90311.1 - 2.3e-36 125.8 0.2 3.1e-36 125.4 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EIM90311.1 - 1.6e-06 27.8 0.0 8.9e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 EIM90311.1 - 1.4e-05 25.4 0.1 0.0019 18.6 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EIM90311.1 - 0.00033 20.3 0.0 0.0025 17.5 0.0 2.5 3 0 0 3 3 3 1 Cupin domain Cupin_1 PF00190.22 EIM90311.1 - 0.046 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 EIM90311.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 EIM90311.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RabGAP-TBC PF00566.18 EIM90312.1 - 2.6e-29 102.4 0.0 1.1e-14 54.7 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF2175 PF09943.9 EIM90312.1 - 1.8 8.9 2.9 3.2 8.1 2.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) MCPVI PF02993.14 EIM90312.1 - 4.6 7.0 9.9 0.5 10.2 4.3 2.1 2 1 0 2 2 2 0 Minor capsid protein VI FAD_binding_2 PF00890.24 EIM90313.1 - 2.7e-126 422.1 3.4 3.4e-126 421.7 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EIM90313.1 - 9.5e-43 145.2 1.0 1.5e-42 144.6 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EIM90313.1 - 7.2e-06 25.3 1.1 0.0097 15.0 2.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EIM90313.1 - 4.6e-05 22.8 0.2 0.032 13.5 0.0 2.6 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 EIM90313.1 - 0.00036 19.9 2.1 0.0018 17.6 0.6 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM90313.1 - 0.0026 17.1 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Nucleoporin_FG2 PF15967.5 EIM90313.1 - 0.015 13.8 0.1 0.023 13.2 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region DAO PF01266.24 EIM90313.1 - 0.11 12.0 2.1 0.39 10.2 2.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM90313.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EIM90313.1 - 0.17 10.6 2.5 0.43 9.2 0.6 2.5 4 0 0 4 4 4 0 HI0933-like protein F-box-like PF12937.7 EIM90314.1 - 0.00022 21.0 0.1 0.0036 17.2 0.1 2.9 1 1 0 1 1 1 1 F-box-like zf-MYND PF01753.18 EIM90316.1 - 2.6e-10 40.2 10.1 2.6e-10 40.2 10.1 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EIM90316.1 - 0.12 12.5 5.0 0.2 11.7 3.7 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Snf7 PF03357.21 EIM90317.1 - 3.1e-13 49.7 11.4 4.9e-13 49.1 11.4 1.3 1 0 0 1 1 1 1 Snf7 SF-assemblin PF06705.11 EIM90317.1 - 0.015 14.7 1.0 0.015 14.7 1.0 2.4 1 1 1 2 2 2 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 EIM90317.1 - 0.58 10.2 2.5 2.2 8.3 1.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPVI PF02993.14 EIM90317.1 - 0.65 9.8 3.7 0.25 11.1 0.5 1.9 2 0 0 2 2 2 0 Minor capsid protein VI COG2 PF06148.11 EIM90317.1 - 4 7.5 10.2 0.21 11.7 0.5 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SKG6 PF08693.10 EIM90318.1 - 0.0072 15.7 2.1 0.016 14.6 2.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain bMG10 PF17973.1 EIM90318.1 - 0.057 13.6 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain PGF-CTERM PF18204.1 EIM90318.1 - 7 6.8 16.4 0.84 9.7 4.7 3.7 3 0 0 3 3 3 0 PGF-CTERM motif PNTB PF02233.16 EIM90319.1 - 2.5e-173 577.2 23.6 2.5e-173 577.2 23.6 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EIM90319.1 - 1.5e-71 240.1 0.2 4.5e-71 238.6 0.2 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EIM90319.1 - 3.2e-43 147.3 0.1 1.1e-42 145.6 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EIM90319.1 - 1.1e-31 109.1 3.4 1.1e-31 109.1 3.4 4.4 2 1 3 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EIM90319.1 - 0.0011 18.3 0.7 1.5 8.2 0.1 3.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EIM90319.1 - 0.0076 15.5 0.2 0.029 13.6 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 EIM90319.1 - 0.17 11.6 0.7 1.2 8.9 0.7 2.5 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 EIM90319.1 - 1.4 8.9 6.2 0.21 11.6 0.4 2.7 3 0 0 3 3 3 0 Zinc-binding dehydrogenase DHDPS PF00701.22 EIM90320.1 - 1.3e-25 89.7 0.0 4.4e-25 88.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family TruB_N PF01509.18 EIM90321.1 - 1.6e-44 151.9 0.0 7.7e-44 149.7 0.0 2.1 2 1 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EIM90321.1 - 1.3e-05 25.3 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UCH PF00443.29 EIM90322.1 - 2.2e-48 165.0 0.0 3.2e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIM90322.1 - 2e-18 67.1 2.0 2.8e-17 63.3 2.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EIM90322.1 - 2.1e-15 56.8 5.5 6.4e-15 55.2 5.5 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein AAA_11 PF13086.6 EIM90322.1 - 0.15 11.8 1.8 0.3 10.9 1.8 1.4 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EIM90322.1 - 0.24 10.1 5.2 0.38 9.5 5.2 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EIM90322.1 - 5.6 4.7 4.3 7.5 4.3 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI3_PI4_kinase PF00454.27 EIM90324.1 - 2.9e-34 119.0 0.1 7.9e-32 111.0 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EIM90324.1 - 3.2e-24 85.4 0.3 8.8e-24 83.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EIM90324.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Aldo_ket_red PF00248.21 EIM90325.1 - 2.4e-33 115.6 0.0 1.2e-32 113.4 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM90326.1 - 4.1e-30 105.0 0.1 2.2e-29 102.6 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4101 PF13355.6 EIM90326.1 - 0.12 12.8 0.1 21 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) Nuc_sug_transp PF04142.15 EIM90328.1 - 5.9e-97 324.6 6.0 2.1e-96 322.8 6.0 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EIM90328.1 - 0.00061 20.0 2.5 0.00061 20.0 2.5 2.7 3 0 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 EIM90328.1 - 0.00083 18.6 6.6 0.0014 17.9 6.6 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EIM90328.1 - 0.011 15.1 2.9 0.13 11.6 0.1 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family PUNUT PF16913.5 EIM90328.1 - 0.035 13.3 8.0 0.012 14.8 4.7 1.8 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport MGC-24 PF05283.11 EIM90330.1 - 0.01 16.3 16.2 0.019 15.4 5.0 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SKG6 PF08693.10 EIM90330.1 - 0.23 10.9 2.3 0.48 9.9 2.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 EIM90330.1 - 1.3 9.0 4.7 5.5 7.0 4.7 2.1 1 1 0 1 1 1 0 LPXTG cell wall anchor motif RAP1 PF07218.11 EIM90330.1 - 5.4 5.2 12.0 9.4 4.4 12.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Exo_endo_phos PF03372.23 EIM90331.1 - 1.8e-14 53.8 0.0 2.3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RLL PF10036.9 EIM90331.1 - 0.23 11.3 0.9 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein PP2C PF00481.21 EIM90334.1 - 2e-10 40.8 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Transket_pyr PF02779.24 EIM90335.1 - 8.1e-40 136.4 0.1 1.5e-39 135.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIM90335.1 - 2.9e-27 95.0 0.0 1.3e-26 92.9 0.0 2.1 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.32 EIM90336.1 - 1e-08 35.7 9.5 0.00035 21.3 0.0 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90336.1 - 2.5e-05 24.5 0.0 0.0083 16.4 0.0 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EIM90336.1 - 0.0025 16.4 0.0 0.02 13.5 0.0 1.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 EIM90336.1 - 0.99 9.4 4.1 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pyr_redox_2 PF07992.14 EIM90337.1 - 1.8e-43 148.9 0.0 3e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EIM90337.1 - 1.2e-10 40.2 2.0 1.4e-05 24.3 0.6 2.4 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.27 EIM90337.1 - 1.2e-10 41.8 0.0 5.2e-07 30.1 0.0 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 EIM90337.1 - 2.3e-08 34.3 3.2 1.2e-06 28.8 0.9 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EIM90337.1 - 3.4e-08 32.8 1.3 0.0031 17.3 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EIM90337.1 - 1.6e-06 27.8 1.0 0.026 14.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EIM90337.1 - 3.3e-06 26.3 2.6 0.00021 20.6 1.0 2.4 2 0 0 2 2 2 1 EF hand NAD_binding_9 PF13454.6 EIM90337.1 - 0.062 13.3 0.1 2.5 8.1 0.0 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EIM90337.1 - 0.092 13.2 0.2 0.5 10.8 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding TPR_17 PF13431.6 EIM90337.1 - 0.17 12.3 0.3 0.55 10.7 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.6 EIM90337.1 - 0.22 10.7 2.5 1.8 7.7 2.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.7 EIM90337.1 - 0.32 11.0 2.7 6.3 6.8 0.6 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.22 EIM90339.1 - 6.5e-59 198.2 0.4 8.2e-59 197.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM90339.1 - 6e-37 126.5 0.1 1.1e-36 125.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM90339.1 - 1.9e-16 60.0 0.6 2.3e-16 59.7 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIM90339.1 - 2.5e-06 27.1 0.1 6.4e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EIM90339.1 - 2.9e-06 27.0 0.6 3.4e-05 23.5 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIM90339.1 - 3.7e-06 26.9 0.3 0.0047 16.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EIM90339.1 - 2.3e-05 24.4 0.1 0.00011 22.2 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIM90339.1 - 4e-05 23.1 0.6 5.6e-05 22.6 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EIM90339.1 - 0.00036 20.1 0.1 0.12 11.9 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 EIM90339.1 - 0.043 13.9 0.1 2.4 8.2 0.0 2.6 2 1 1 3 3 3 0 Dynamin family TniB PF05621.11 EIM90339.1 - 0.056 12.9 0.1 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EIM90339.1 - 0.059 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EIM90339.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain MTHFR PF02219.17 EIM90340.1 - 4.6e-108 360.9 0.0 5.9e-108 360.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ANAPC15 PF15243.6 EIM90341.1 - 7.8e-05 23.0 0.0 7.8e-05 23.0 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 15 PI3K_1B_p101 PF10486.9 EIM90341.1 - 1.7 6.3 7.2 2 6.1 7.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2722 PF10846.8 EIM90341.1 - 5.1 5.9 8.7 6.4 5.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ATP-synt_ab PF00006.25 EIM90342.1 - 2.2e-63 213.7 0.0 4.1e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EIM90342.1 - 1.6e-22 79.8 2.6 1.8e-22 79.6 0.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EIM90342.1 - 0.0054 15.9 0.6 0.012 14.8 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 EIM90342.1 - 0.0084 16.5 0.0 0.42 11.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM90342.1 - 0.024 15.0 0.1 0.086 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EIM90342.1 - 0.026 14.4 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EIM90342.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EIM90342.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EIM90342.1 - 0.067 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EIM90342.1 - 0.081 13.3 0.7 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 EIM90342.1 - 0.23 11.3 0.4 0.88 9.5 0.4 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain CLP1_P PF16575.5 EIM90343.1 - 5.9e-33 114.2 0.0 1e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EIM90343.1 - 2.9e-32 110.8 0.0 4.8e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EIM90343.1 - 1.1e-28 100.0 0.0 1.8e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Gtr1_RagA PF04670.12 EIM90343.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIM90343.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EIM90343.1 - 0.073 12.8 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EIM90343.1 - 0.088 13.2 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Egh16-like PF11327.8 EIM90344.1 - 3.2e-53 180.9 9.0 4e-53 180.6 9.0 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor TAP42 PF04177.12 EIM90345.1 - 1.8e-88 296.8 3.5 2e-88 296.6 3.5 1.0 1 0 0 1 1 1 1 TAP42-like family POT1PC PF16686.5 EIM90346.1 - 5.1e-16 58.9 1.7 2.3e-07 30.8 0.1 4.8 3 2 0 3 3 3 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EIM90346.1 - 6.5e-10 39.0 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 EIM90346.1 - 0.0018 18.2 0.0 0.0052 16.7 0.0 1.8 1 0 0 1 1 1 1 Replication protein A OB domain Peptidase_S8 PF00082.22 EIM90347.1 - 2.1e-28 99.5 0.4 3.1e-28 98.9 0.4 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EIM90347.1 - 1.3e-26 92.4 0.3 3e-26 91.2 0.3 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 EIM90347.1 - 0.0085 16.6 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal of Subtilase family DUF2914 PF11141.8 EIM90347.1 - 0.06 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) S8_pro-domain PF16470.5 EIM90347.1 - 3 8.7 7.2 7.1 7.5 3.9 3.1 2 1 0 2 2 2 0 Peptidase S8 pro-domain MCM PF00493.23 EIM90348.1 - 7.7e-105 348.9 0.0 1.3e-104 348.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIM90348.1 - 9.3e-31 106.3 0.3 1.6e-30 105.5 0.3 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIM90348.1 - 3.4e-21 75.4 2.2 1.2e-20 73.7 2.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIM90348.1 - 5.4e-19 68.7 0.5 1.5e-18 67.3 0.5 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EIM90348.1 - 1.4e-09 38.1 0.4 1.1e-06 28.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EIM90348.1 - 1.2e-07 31.3 0.1 1.1e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EIM90348.1 - 0.02 14.8 0.0 0.065 13.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EIM90348.1 - 0.022 14.6 0.2 0.075 12.9 0.2 1.9 1 0 0 1 1 1 0 AAA lid domain PI-TkoII_IV PF18714.1 EIM90348.1 - 0.023 14.2 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Sigma54_activat PF00158.26 EIM90348.1 - 0.057 13.1 0.7 0.68 9.6 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_polI_A14 PF08203.11 EIM90348.1 - 0.15 12.8 0.1 0.68 10.7 0.0 2.2 2 0 0 2 2 1 0 Yeast RNA polymerase I subunit RPA14 PBP1_TM PF14812.6 EIM90348.1 - 3.3 8.2 13.3 2.1 8.8 8.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mg_chelatase_C PF13335.6 EIM90348.1 - 5.6 7.7 11.9 0.12 13.0 1.0 3.4 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI C-terminal DNA_methylase PF00145.17 EIM90349.1 - 5.2e-49 167.4 0.0 1.2e-48 166.2 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EIM90349.1 - 6.5e-17 61.5 0.2 3.6e-10 39.8 0.1 3.0 3 0 0 3 3 3 2 BAH domain DNMT1-RFD PF12047.8 EIM90349.1 - 1.2e-06 28.7 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain APG9 PF04109.16 EIM90350.1 - 6.3e-208 691.6 5.1 7.6e-208 691.3 5.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Thiamine_BP PF01910.17 EIM90351.1 - 6.6e-28 96.5 0.0 7.8e-28 96.2 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 EIM90351.1 - 0.0002 21.7 0.0 0.00024 21.5 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family adh_short PF00106.25 EIM90352.1 - 3e-31 108.4 0.0 1.1e-24 87.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90352.1 - 2.5e-21 76.3 0.0 3.6e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM90352.1 - 5.1e-07 29.8 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EIM90352.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EIM90352.1 - 0.062 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 EIM90353.1 - 6.8e-46 156.8 0.0 9.3e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90353.1 - 6.6e-45 153.4 0.0 8.3e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM90353.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM90353.1 - 0.0085 16.0 0.0 0.03 14.2 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM90353.1 - 0.02 13.7 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase SAP PF02037.27 EIM90353.1 - 0.021 14.6 0.1 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 SAP domain Seadorna_VP7 PF07387.11 EIM90353.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Mito_carr PF00153.27 EIM90354.1 - 2.6e-52 174.7 4.9 3.2e-18 65.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1c PF00749.21 EIM90355.1 - 4.7e-111 370.6 0.0 6.3e-111 370.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EIM90355.1 - 2e-36 125.5 0.0 3.9e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 EIM90355.1 - 0.00043 20.4 0.8 0.025 14.8 0.0 3.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM90355.1 - 0.00059 20.0 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM90355.1 - 0.00098 19.1 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EIM90355.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HMGL-like PF00682.19 EIM90356.1 - 2.3e-71 240.5 0.0 4e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EIM90356.1 - 1.1e-35 122.5 0.0 1.8e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain AAA PF00004.29 EIM90357.1 - 7.3e-14 52.3 0.0 1.4e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EIM90357.1 - 4.1e-07 30.1 0.1 6.5e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EIM90357.1 - 1e-05 25.3 0.0 3.4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EIM90357.1 - 8.3e-05 22.6 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EIM90357.1 - 0.00039 20.5 0.0 0.00072 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM90357.1 - 0.00055 20.4 0.0 0.0017 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 EIM90357.1 - 0.0013 19.1 0.0 0.0038 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_25 PF13481.6 EIM90357.1 - 0.0017 17.9 0.0 0.32 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM90357.1 - 0.0023 18.2 0.0 0.016 15.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EIM90357.1 - 0.0025 18.0 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EIM90357.1 - 0.02 14.2 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EIM90357.1 - 0.022 14.5 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EIM90357.1 - 0.023 15.2 0.0 0.11 13.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EIM90357.1 - 0.028 14.3 0.1 0.15 12.0 0.0 2.1 1 1 1 2 2 2 0 NTPase AAA_17 PF13207.6 EIM90357.1 - 0.049 14.1 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIM90357.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 EIM90357.1 - 0.099 12.7 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EIM90357.1 - 0.12 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EIM90357.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MFS_1 PF07690.16 EIM90358.1 - 2.6e-23 82.5 27.9 1.5e-22 80.0 28.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CRPA PF05745.11 EIM90358.1 - 0.63 10.0 4.5 6.4 6.8 0.7 2.4 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) His_Phos_1 PF00300.22 EIM90359.1 - 2e-26 92.9 1.5 1.2e-24 87.1 1.5 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PYST-C1 PF09690.10 EIM90360.1 - 1.9 8.3 8.0 46 3.9 8.3 2.4 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) TAFII55_N PF04658.13 EIM90361.1 - 1.3e-56 190.8 0.2 1.3e-56 190.8 0.2 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region THOC2_N PF16134.5 EIM90361.1 - 1.5 7.4 4.2 2.2 6.8 4.2 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus SIR4_SID PF16991.5 EIM90361.1 - 5.9 6.9 12.0 4.5 7.3 6.9 2.7 3 0 0 3 3 3 0 Sir4 SID domain Tom37 PF10568.9 EIM90362.1 - 5.7e-26 91.3 0.1 9.3e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EIM90362.1 - 6.7e-12 45.0 0.1 1.4e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EIM90362.1 - 6.1e-06 26.9 0.0 0.00066 20.4 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 EIM90362.1 - 0.00015 21.7 0.1 0.00044 20.2 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TyeA PF09059.10 EIM90362.1 - 0.086 13.0 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 TyeA OTU PF02338.19 EIM90363.1 - 1.1e-05 25.9 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease CENP-K PF11802.8 EIM90364.1 - 0.012 15.2 4.4 0.024 14.2 4.4 1.4 1 0 0 1 1 1 0 Centromere-associated protein K Chromo PF00385.24 EIM90364.1 - 0.023 14.6 1.3 0.048 13.6 0.8 1.8 2 0 0 2 2 1 0 Chromo (CHRromatin Organisation MOdifier) domain Golgin_A5 PF09787.9 EIM90364.1 - 0.12 11.8 16.3 0.15 11.5 8.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 EIM90364.1 - 0.13 12.4 11.2 0.29 11.4 11.2 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Leu_zip PF15294.6 EIM90364.1 - 0.14 11.6 7.1 0.24 10.9 7.1 1.3 1 0 0 1 1 1 0 Leucine zipper Fib_alpha PF08702.10 EIM90364.1 - 0.2 11.9 5.4 0.39 10.9 5.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EIM90364.1 - 0.25 10.2 10.6 0.4 9.5 10.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.16 EIM90364.1 - 0.26 11.5 11.3 0.56 10.4 11.3 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein AAA_13 PF13166.6 EIM90364.1 - 0.5 9.0 5.5 0.76 8.3 5.5 1.2 1 0 0 1 1 1 0 AAA domain YlqD PF11068.8 EIM90364.1 - 0.78 10.1 8.4 2 8.8 8.4 1.7 1 0 0 1 1 1 0 YlqD protein TMPIT PF07851.13 EIM90364.1 - 1.1 8.5 5.2 1.9 7.6 5.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EIM90364.1 - 2.5 7.4 12.8 12 5.1 12.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 EIM90364.1 - 3.4 5.5 3.7 5 4.9 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 EIM90364.1 - 3.8 7.6 11.1 91 3.1 11.2 2.7 1 1 0 1 1 1 0 FlxA-like protein UPF0242 PF06785.11 EIM90364.1 - 5.4 7.1 12.1 9.9 6.2 12.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 EIM90364.1 - 5.8 6.6 10.6 1.1e+02 2.4 10.8 2.2 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Csm1_N PF18504.1 EIM90364.1 - 7.1 7.1 10.1 7.2 7.0 1.8 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Cluap1 PF10234.9 EIM90364.1 - 8.4 5.7 14.1 3.7 6.8 3.5 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 Sugar_tr PF00083.24 EIM90365.1 - 2.9e-93 313.2 24.4 3.5e-93 312.9 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM90365.1 - 5e-34 117.8 29.1 9.5e-34 116.9 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EIM90365.1 - 1.1e-07 30.6 17.4 6.3e-05 21.5 0.9 3.2 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_2 PF04550.12 EIM90365.1 - 0.018 15.6 6.3 0.086 13.4 0.7 3.3 3 1 0 3 3 3 0 Phage holin family 2 MFS_3 PF05977.13 EIM90365.1 - 1.3 7.3 13.5 0.022 13.2 5.8 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector HECT PF00632.25 EIM90366.1 - 2.8e-90 302.9 0.0 4.1e-90 302.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EIM90366.1 - 1.9e-37 127.0 19.3 2.6e-13 49.8 5.1 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EIM90366.1 - 2.7e-20 72.6 0.2 8e-20 71.1 0.2 1.8 1 0 0 1 1 1 1 C2 domain Nt_Gln_amidase PF09764.9 EIM90368.1 - 3.6e-28 98.4 0.4 4.3e-28 98.2 0.4 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase ANAPC3 PF12895.7 EIM90368.1 - 0.017 15.4 0.1 0.024 14.9 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Gln_deamidase_2 PF18626.1 EIM90368.1 - 0.039 14.2 0.1 0.05 13.9 0.1 1.2 1 0 0 1 1 1 0 Glutaminase CENP-B_dimeris PF09026.10 EIM90370.1 - 5.9 7.3 8.9 29 5.1 8.9 2.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UQ_con PF00179.26 EIM90371.1 - 2.9e-42 143.6 0.1 3.3e-42 143.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EIM90371.1 - 0.00078 19.7 0.0 0.00093 19.5 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EIM90371.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 EIM90371.1 - 0.003 17.3 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B SPRY PF00622.28 EIM90372.1 - 1.4e-05 25.2 0.0 0.056 13.6 0.0 3.2 3 0 0 3 3 3 2 SPRY domain PhoD PF09423.10 EIM90373.1 - 0.00066 18.8 0.1 0.18 10.8 0.1 2.4 2 0 0 2 2 2 2 PhoD-like phosphatase DprA_WH PF17782.1 EIM90373.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 DprA winged helix domain CAP_N PF01213.19 EIM90374.1 - 5.4e-92 308.7 0.0 7.9e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EIM90374.1 - 1.5e-56 190.4 4.8 2e-56 190.0 4.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EIM90374.1 - 0.025 14.3 3.5 0.065 13.0 3.5 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor C Matrilin_ccoil PF10393.9 EIM90374.1 - 0.18 11.7 0.5 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin RF-1 PF00472.20 EIM90375.1 - 9.5e-23 80.3 4.8 9.5e-23 80.3 4.8 2.1 2 1 1 3 3 3 1 RF-1 domain Linker_histone PF00538.19 EIM90376.1 - 3.5e-25 88.2 0.5 1e-24 86.7 0.0 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 EIM90376.1 - 0.49 10.4 89.1 0.54 10.3 6.2 2.4 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 EI24 PF07264.11 EIM90377.1 - 7.9e-35 120.7 12.2 1e-34 120.3 12.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.24 EIM90378.1 - 1.3e-25 90.7 16.4 1.3e-25 90.7 16.4 1.8 2 0 0 2 2 2 1 Fatty acid desaturase Lipase_GDSL_2 PF13472.6 EIM90379.1 - 1.4e-29 103.8 0.0 3.6e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIM90379.1 - 2.3e-20 73.5 0.0 3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.20 EIM90380.1 - 1.2e-12 48.2 0.0 2.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain AAA PF00004.29 EIM90382.1 - 6.6e-20 71.9 0.0 1.5e-19 70.7 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EIM90382.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 EIM90382.1 - 0.06 13.7 1.2 0.66 10.3 0.0 2.7 3 1 1 4 4 4 0 AAA ATPase domain AAA_5 PF07728.14 EIM90382.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pox_MCEL PF03291.16 EIM90383.1 - 5e-84 282.3 0.0 6.5e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EIM90383.1 - 7.7e-11 42.6 0.0 1.6e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM90383.1 - 1e-08 35.8 0.0 1.7e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM90383.1 - 2.7e-07 30.5 0.0 4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM90383.1 - 1.1e-05 25.3 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM90383.1 - 3.4e-05 24.4 0.0 6.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EIM90383.1 - 0.25 11.3 0.0 0.52 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EIM90383.1 - 0.27 10.4 0.0 0.43 9.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family YkyA PF10368.9 EIM90385.1 - 0.12 12.0 4.0 0.29 10.8 4.0 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein TEA PF01285.18 EIM90386.1 - 2e-23 82.2 0.1 4.1e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 TEA/ATTS domain ER_lumen_recept PF00810.18 EIM90387.1 - 2.3e-10 41.5 1.5 4e-10 40.7 0.0 2.0 1 1 1 2 2 2 1 ER lumen protein retaining receptor Bestrophin PF01062.21 EIM90388.1 - 1.4e-39 136.2 0.1 2.9e-22 79.4 0.0 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel 12TM_1 PF09847.9 EIM90388.1 - 0.012 14.7 2.0 0.019 14.1 2.0 1.2 1 0 0 1 1 1 0 Membrane protein of 12 TMs hNIFK_binding PF12196.8 EIM90388.1 - 0.14 11.6 0.3 0.28 10.7 0.3 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK S-AdoMet_synt_M PF02772.16 EIM90388.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain 2Fe-2S_thioredx PF01257.19 EIM90389.1 - 2.5e-58 196.1 0.0 3e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Telomere_reg-2 PF10193.9 EIM90390.1 - 9.9e-32 109.6 0.1 3.2e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 Telomere length regulation protein Linker_histone PF00538.19 EIM90391.1 - 6.5e-22 77.7 0.2 2.4e-21 75.9 0.0 2.1 2 1 1 3 3 3 1 linker histone H1 and H5 family AMP-binding PF00501.28 EIM90392.1 - 5.1e-19 68.2 0.0 1.8e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme DPBB_1 PF03330.18 EIM90394.1 - 0.00014 22.1 0.1 0.0004 20.6 0.1 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM90394.1 - 0.022 14.6 0.2 0.027 14.3 0.2 1.2 1 0 0 1 1 1 0 Barwin family zf-ribbon_3 PF13248.6 EIM90394.1 - 0.028 13.8 1.0 24 4.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 EIM90394.1 - 0.072 13.0 0.6 0.14 12.1 0.6 1.5 1 1 0 1 1 1 0 Cysteine-rich CPXCG Linker_histone PF00538.19 EIM90395.1 - 6.8e-21 74.4 0.0 6.8e-21 74.4 0.0 2.3 3 0 0 3 3 3 1 linker histone H1 and H5 family Pkinase PF00069.25 EIM90396.1 - 9.1e-46 156.3 0.0 1.2e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90396.1 - 7.9e-18 64.7 0.0 1.3e-17 63.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM90396.1 - 1.2e-07 31.4 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM90396.1 - 3.6e-05 23.2 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM90396.1 - 0.00019 21.4 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EIM90396.1 - 0.053 13.1 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PVL_ORF50 PF07768.11 EIM90397.1 - 1.7 8.9 5.4 1.4 9.2 0.3 2.4 2 0 0 2 2 2 0 PVL ORF-50-like family RRM_1 PF00076.22 EIM90398.1 - 2.9e-25 87.9 0.0 1.5e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 EIM90398.1 - 8.7e-20 69.2 0.0 0.00021 20.8 0.0 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 EIM90398.1 - 1.4e-05 24.8 0.0 0.14 12.1 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 EIM90398.1 - 0.056 12.9 0.0 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif HTH_21 PF13276.6 EIM90398.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain DUF2514 PF10721.9 EIM90399.1 - 0.067 13.2 1.2 0.098 12.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Mog1 PF04603.12 EIM90400.1 - 1.1e-40 139.2 0.1 1.3e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ndc80_HEC PF03801.13 EIM90401.1 - 4.2e-30 104.4 0.0 8.8e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 EIM90401.1 - 0.0001 22.3 6.8 0.0001 22.3 6.8 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF5595) DHR10 PF18595.1 EIM90401.1 - 0.0058 16.7 6.3 0.0058 16.7 6.3 4.3 2 2 2 4 4 4 1 Designed helical repeat protein 10 domain DUF2710 PF10921.8 EIM90401.1 - 0.074 13.5 1.6 0.14 12.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) Flagellin_N PF00669.20 EIM90401.1 - 0.078 13.1 13.6 0.24 11.5 0.7 3.1 3 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region TraF_2 PF13729.6 EIM90401.1 - 0.13 11.6 9.7 0.33 10.3 1.2 3.0 2 1 2 4 4 4 0 F plasmid transfer operon, TraF, protein Seryl_tRNA_N PF02403.22 EIM90401.1 - 0.16 12.2 29.3 0.027 14.7 7.9 3.8 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 EIM90401.1 - 0.23 12.4 29.9 0.26 12.2 4.8 4.7 3 2 1 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF2730 PF10805.8 EIM90401.1 - 0.79 9.9 11.9 1.1 9.3 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) CK2S PF15011.6 EIM90401.1 - 0.96 9.3 13.7 0.38 10.6 1.8 3.4 3 1 0 3 3 3 0 Casein Kinase 2 substrate DUF4988 PF16378.5 EIM90401.1 - 2.9 7.5 6.7 0.22 11.2 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function Spectrin PF00435.21 EIM90401.1 - 3.4 8.2 24.0 0.24 11.9 2.7 4.0 2 1 0 3 3 3 0 Spectrin repeat TSC22 PF01166.18 EIM90401.1 - 4.1 7.8 12.4 0.17 12.2 1.7 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family NPV_P10 PF05531.12 EIM90401.1 - 9.3 6.8 10.4 0.68 10.4 0.4 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein LktC PF06261.11 EIM90402.1 - 0.015 15.2 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Ferric_reduct PF01794.19 EIM90402.1 - 0.34 11.0 9.9 0.35 11.0 7.8 2.1 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF2235 PF09994.9 EIM90403.1 - 3.6e-72 243.2 0.0 4.5e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) KAR9 PF08580.10 EIM90404.1 - 1.1 7.8 15.8 1 7.8 15.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RCC1 PF00415.18 EIM90405.1 - 3.2e-20 72.5 10.5 2.8e-07 31.1 0.3 8.0 9 0 0 9 9 9 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIM90405.1 - 4.4e-12 45.5 18.1 7.7e-06 25.6 0.1 7.6 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat Nucleoporin_N PF08801.11 EIM90405.1 - 0.0017 17.2 0.0 0.0036 16.1 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Ad_Cy_reg PF16701.5 EIM90406.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain DUF3599 PF12206.8 EIM90406.1 - 0.048 14.0 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) DSBA PF01323.20 EIM90406.1 - 0.14 12.0 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain F-box-like PF12937.7 EIM90407.1 - 2.3e-05 24.2 0.0 0.0001 22.1 0.0 2.1 1 1 0 1 1 1 1 F-box-like NRBF2_MIT PF17169.4 EIM90410.1 - 3.8e-07 30.2 0.7 3.8e-07 30.2 0.7 2.2 2 0 0 2 2 1 1 MIT domain of nuclear receptor-binding factor 2 DUF5320 PF17253.2 EIM90410.1 - 0.015 16.3 0.3 0.35 12.0 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Rx_N PF18052.1 EIM90410.1 - 0.02 15.2 0.5 0.02 15.2 0.5 3.0 3 0 0 3 3 3 0 Rx N-terminal domain TolA_bind_tri PF16331.5 EIM90410.1 - 0.06 13.4 4.8 5.1 7.2 0.1 3.0 3 0 0 3 3 3 0 TolA binding protein trimerisation Thiamine_BP PF01910.17 EIM90410.1 - 0.062 13.2 0.3 0.062 13.2 0.3 2.4 3 0 0 3 3 3 0 Thiamine-binding protein PaREP1 PF05942.11 EIM90410.1 - 0.064 13.2 0.3 0.064 13.2 0.3 2.9 3 0 0 3 3 3 0 Archaeal PaREP1/PaREP8 family BRI3BP PF14965.6 EIM90410.1 - 0.083 12.4 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Uso1_p115_C PF04871.13 EIM90410.1 - 0.084 13.2 0.3 0.084 13.2 0.3 3.5 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2383 PF09537.10 EIM90410.1 - 0.087 13.2 10.3 0.18 12.2 1.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF2383) Fez1 PF06818.15 EIM90410.1 - 0.22 12.0 17.7 0.11 12.9 12.7 2.6 2 1 0 2 2 2 0 Fez1 WD40_alt PF14077.6 EIM90410.1 - 0.26 11.2 7.5 0.42 10.5 2.0 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF4407 PF14362.6 EIM90410.1 - 0.28 10.5 12.3 0.036 13.4 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HemX PF04375.14 EIM90410.1 - 0.5 9.6 12.5 0.97 8.6 0.0 3.3 3 1 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMF_TATA_bd PF12325.8 EIM90410.1 - 0.76 10.0 18.1 0.6 10.4 0.3 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 EIM90410.1 - 0.96 10.1 12.0 22 5.8 0.2 3.6 3 0 0 3 3 3 0 Initiation control protein YabA Med9 PF07544.13 EIM90410.1 - 1.1 9.4 12.1 1.8 8.7 1.2 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Cep57_MT_bd PF06657.13 EIM90410.1 - 1.5 9.3 14.3 0.15 12.6 0.7 3.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.11 EIM90410.1 - 1.6 9.2 16.4 1.3 9.4 0.6 3.8 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 EIM90410.1 - 1.7 9.2 8.9 0.96 10.0 0.6 3.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.9 EIM90410.1 - 2.7 8.2 16.9 3.4 7.9 4.6 3.3 2 1 1 3 3 3 0 Zinc finger-containing protein DUF3450 PF11932.8 EIM90410.1 - 2.8 7.2 14.5 1 8.6 3.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 EIM90410.1 - 4.8 7.3 21.3 0.94 9.6 3.3 4.0 3 2 1 4 4 4 0 bZIP transcription factor End3 PF12761.7 EIM90410.1 - 5.7 7.1 13.1 3.8 7.6 0.5 3.4 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Seryl_tRNA_N PF02403.22 EIM90410.1 - 7.1 6.9 25.4 5 7.4 0.9 3.8 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.9 EIM90410.1 - 7.4 6.5 18.2 2.1 8.3 0.4 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain HAUS6_N PF14661.6 EIM90412.1 - 3.7e-10 39.8 0.0 0.00014 21.5 0.0 3.1 3 0 0 3 3 3 2 HAUS augmin-like complex subunit 6 N-terminus Cpn60_TCP1 PF00118.24 EIM90413.1 - 1.1e-147 492.6 12.8 1.3e-147 492.5 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EIM90413.1 - 0.0036 16.8 0.0 0.009 15.5 0.0 1.7 1 0 0 1 1 1 1 Telomere recombination TPR_2 PF07719.17 EIM90414.1 - 7.5e-27 91.3 9.5 0.00026 20.9 0.3 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 EIM90414.1 - 2.2e-24 84.2 4.9 1.9e-07 30.6 0.4 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM90414.1 - 1.8e-18 66.5 10.5 1.7e-11 44.1 0.1 5.6 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EIM90414.1 - 9.9e-18 64.5 32.7 3e-05 24.6 0.1 8.7 8 1 1 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 EIM90414.1 - 5.8e-17 60.8 0.3 0.096 13.1 0.1 7.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EIM90414.1 - 1.2e-16 60.0 0.1 0.0028 17.3 0.0 6.8 5 1 1 6 6 6 4 TPR repeat TPR_8 PF13181.6 EIM90414.1 - 2.8e-16 58.3 1.3 0.59 10.5 0.2 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM90414.1 - 9.4e-16 58.1 14.3 2.3e-05 24.8 0.0 8.2 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EIM90414.1 - 2.2e-14 52.9 22.4 0.0063 17.2 0.2 10.0 5 2 6 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EIM90414.1 - 1.2e-08 35.1 19.0 0.00079 19.7 0.2 8.3 5 1 4 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIM90414.1 - 2.9e-08 33.8 11.5 6.8 7.6 0.0 8.8 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIM90414.1 - 2.9e-07 30.0 13.9 0.18 11.0 0.1 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EIM90414.1 - 3.7e-06 27.0 14.6 0.0016 18.5 0.3 5.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIM90414.1 - 3.3e-05 23.6 4.3 18 5.6 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EIM90414.1 - 0.0011 18.5 1.7 1.4 8.6 0.1 2.8 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) Phage_integrase PF00589.22 EIM90414.1 - 0.035 13.9 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Phage integrase family TBCC_N PF16752.5 EIM90414.1 - 0.069 13.6 0.4 0.23 11.9 0.4 1.8 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain PPTA PF01239.22 EIM90414.1 - 0.14 12.0 0.1 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat BTAD PF03704.17 EIM90414.1 - 0.56 10.6 12.7 28 5.1 0.8 5.7 5 2 1 6 6 6 0 Bacterial transcriptional activator domain SMAP PF15477.6 EIM90414.1 - 1.7 9.7 3.6 1.1e+02 3.8 5.3 2.9 2 1 0 2 2 2 0 Small acidic protein family SIN1 PF05422.12 EIM90415.1 - 0.21 12.1 2.4 16 6.1 0.1 2.3 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) SRR1 PF07985.12 EIM90416.1 - 4.6e-16 58.6 0.2 8.4e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 SRR1 SANT_DAMP1_like PF16282.5 EIM90416.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Pre-PUA PF17832.1 EIM90417.1 - 1e-24 87.0 0.1 1.4e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EIM90417.1 - 1.4e-15 57.0 0.0 2.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 PUA domain Pkinase PF00069.25 EIM90418.1 - 8e-26 91.0 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90418.1 - 4.2e-11 42.6 0.0 5.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM90418.1 - 3e-05 23.5 0.0 4.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIM90418.1 - 0.02 14.8 0.1 0.067 13.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Trp_halogenase PF04820.14 EIM90418.1 - 0.049 12.5 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Kdo PF06293.14 EIM90418.1 - 0.061 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIM90418.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4698 PF15769.5 EIM90418.1 - 0.094 11.8 0.5 0.13 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) RIO1 PF01163.22 EIM90418.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DPBB_1 PF03330.18 EIM90419.1 - 0.046 14.0 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase HSP70 PF00012.20 EIM90420.1 - 4.4e-238 791.4 5.0 5.4e-238 791.1 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIM90420.1 - 2.3e-16 59.5 0.2 2.5e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 EIM90420.1 - 0.0049 16.4 0.2 1.8 8.0 0.0 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 EIM90420.1 - 0.011 14.8 0.4 0.096 11.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 EIM90420.1 - 0.026 14.2 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EIM90420.1 - 0.054 12.8 0.2 0.11 11.7 0.2 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Gag_p24 PF00607.20 EIM90420.1 - 0.079 12.8 0.3 1.9 8.3 0.3 2.3 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) DUF1539 PF07560.11 EIM90420.1 - 0.11 12.6 0.2 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) StbA PF06406.11 EIM90420.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 StbA protein Chorismate_bind PF00425.18 EIM90421.1 - 3.1e-89 298.9 0.0 6.6e-89 297.9 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EIM90421.1 - 8.2e-27 94.2 0.0 2.9e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region SHQ1 PF04925.15 EIM90422.1 - 1.7e-53 180.8 0.0 3.5e-53 179.8 0.0 1.5 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 EIM90422.1 - 4.6e-05 23.8 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 EIM90422.1 - 0.0003 21.7 0.0 0.00054 20.9 0.0 1.5 1 0 0 1 1 1 1 CS domain ArsA_HSP20 PF17886.1 EIM90422.1 - 0.0046 16.5 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Pkinase PF00069.25 EIM90423.1 - 1.2e-38 133.0 0.0 2.1e-38 132.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90423.1 - 8.5e-20 71.1 0.0 1.3e-19 70.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM90423.1 - 0.00085 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM90423.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM90423.1 - 0.023 14.6 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.20 EIM90424.1 - 1.4e-52 177.8 0.9 1.4e-52 177.8 0.9 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EIM90424.1 - 4.5e-45 153.6 9.0 4.5e-45 153.6 9.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EIM90424.1 - 4.1e-22 79.5 0.2 2.6e-21 76.9 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIM90424.1 - 4.2e-21 74.4 0.1 2e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EIM90424.1 - 1.3e-18 66.9 0.0 2.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EIM90424.1 - 2.9e-06 27.2 1.7 4.8e-06 26.5 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EIM90424.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 EIM90424.1 - 0.15 12.4 8.2 0.18 12.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) zf-C3HC4_3 PF13920.6 EIM90425.1 - 0.041 13.8 10.5 0.072 13.0 10.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 EIM90425.1 - 0.1 13.1 0.4 0.27 11.7 0.4 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain PEHE PF15275.6 EIM90425.1 - 0.11 13.1 1.2 0.32 11.6 1.2 1.9 1 0 0 1 1 1 0 PEHE domain Lactamase_B PF00753.27 EIM90426.1 - 2e-13 50.8 0.3 4.2e-12 46.5 0.3 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIM90426.1 - 0.0076 15.8 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DPBB_1 PF03330.18 EIM90428.1 - 0.0022 18.2 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase SOG2 PF10428.9 EIM90428.1 - 0.19 10.9 18.2 0.21 10.8 18.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 EIM90428.1 - 0.86 8.1 7.8 0.82 8.2 7.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EIM90428.1 - 4 6.2 10.3 4.7 5.9 10.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DPBB_1 PF03330.18 EIM90429.1 - 0.0025 18.1 0.1 0.0089 16.3 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EIM90429.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Barwin family AAA PF00004.29 EIM90431.1 - 6.5e-15 55.7 0.0 2.5e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EIM90431.1 - 1e-11 45.1 0.2 2.5e-11 43.8 0.2 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EIM90431.1 - 1.1e-11 44.8 0.0 6e-10 39.1 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EIM90431.1 - 5.7e-08 32.9 0.0 1.9e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EIM90431.1 - 2.9e-06 27.5 0.0 8.9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 EIM90431.1 - 5e-06 26.8 0.0 3.6e-05 24.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIM90431.1 - 9.3e-06 26.1 0.2 0.00011 22.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 EIM90431.1 - 0.00011 22.1 0.0 0.00026 20.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EIM90431.1 - 0.00012 21.9 0.0 0.00063 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_lid_2 PF17863.1 EIM90431.1 - 0.00014 21.7 0.1 0.00033 20.4 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain RuvB_N PF05496.12 EIM90431.1 - 0.00026 20.8 0.1 0.00067 19.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EIM90431.1 - 0.00033 20.4 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EIM90431.1 - 0.00046 20.2 0.0 0.0026 17.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EIM90431.1 - 0.0031 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EIM90431.1 - 0.0034 16.8 0.0 0.084 12.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EIM90431.1 - 0.0057 16.7 0.0 0.031 14.3 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIM90431.1 - 0.013 15.8 0.1 0.12 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EIM90431.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EIM90431.1 - 0.036 14.3 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EIM90431.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 EIM90431.1 - 0.037 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.29 EIM90431.1 - 0.043 13.6 0.3 0.36 10.6 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_18 PF13238.6 EIM90431.1 - 0.049 14.2 0.1 0.2 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain PreAtp-grasp PF18604.1 EIM90431.1 - 0.11 12.1 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 Pre ATP-grasp domain AAA_23 PF13476.6 EIM90431.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CAF1A PF12253.8 EIM90432.1 - 1.2e-24 86.3 4.4 1.2e-24 86.3 4.4 2.8 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A DUF2076 PF09849.9 EIM90432.1 - 0.00026 21.2 1.3 0.00026 21.2 1.3 2.3 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF4551 PF15087.6 EIM90432.1 - 0.69 8.7 11.3 1.5 7.5 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4337 PF14235.6 EIM90432.1 - 9.3 6.3 7.7 20 5.3 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PRP21_like_P PF12230.8 EIM90434.1 - 5.3e-49 167.0 13.8 5.3e-49 167.0 13.8 3.0 2 1 1 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EIM90434.1 - 4.5e-34 116.2 1.5 1.6e-17 63.2 0.1 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EIM90434.1 - 2.7e-06 27.0 0.0 6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 EIM90434.1 - 0.00082 18.9 0.1 0.0018 17.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 EIM90434.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Med19 PF10278.9 EIM90434.1 - 4.3 7.2 16.5 0.15 12.0 0.6 3.3 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 L31 PF09784.9 EIM90435.1 - 2.9e-41 140.0 0.2 3.2e-41 139.9 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.6 EIM90436.1 - 4.2e-56 190.1 13.4 5.6e-36 124.2 0.1 3.1 3 0 0 3 3 3 3 U3-containing 90S pre-ribosomal complex subunit Nop14 PF04147.12 EIM90436.1 - 0.00093 17.6 1.8 0.0011 17.3 1.8 1.1 1 0 0 1 1 1 1 Nop14-like family Rrn6 PF10214.9 EIM90436.1 - 0.0051 15.4 6.8 0.0086 14.6 6.8 1.3 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor LRIF1 PF15741.5 EIM90436.1 - 0.033 12.8 4.5 0.048 12.2 4.5 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 U3_snoRNA_assoc PF08297.11 EIM90436.1 - 0.093 13.5 10.3 0.3 11.8 7.8 2.4 2 0 0 2 2 2 0 U3 snoRNA associated CDC45 PF02724.14 EIM90436.1 - 0.41 8.9 6.5 0.52 8.5 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3153 PF11353.8 EIM90436.1 - 0.43 10.1 1.3 7.8 6.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3153) ATP-synt_E PF05680.12 EIM90436.1 - 1.9 8.9 8.3 3.5 8.0 8.3 1.4 1 0 0 1 1 1 0 ATP synthase E chain Med19 PF10278.9 EIM90436.1 - 2 8.3 10.5 3.6 7.5 10.5 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nucleo_P87 PF07267.11 EIM90436.1 - 3.8 6.2 7.2 5.5 5.7 7.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RNase_T PF00929.24 EIM90437.1 - 1.9e-14 54.6 0.0 7.3e-14 52.6 0.0 1.8 1 1 0 1 1 1 1 Exonuclease CRM1_C PF08767.11 EIM90438.1 - 1.2e-129 432.1 4.5 3e-129 430.8 0.1 3.3 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EIM90438.1 - 2.2e-41 141.4 9.8 5.1e-41 140.2 7.3 3.0 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EIM90438.1 - 5.5e-34 115.6 4.0 1.7e-33 114.0 4.0 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EIM90438.1 - 1.5e-29 101.8 0.8 1.5e-29 101.8 0.8 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EIM90438.1 - 2.6e-19 68.4 2.8 2.6e-19 68.4 2.8 2.3 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EIM90438.1 - 1.4e-14 53.7 0.0 6.9e-14 51.5 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EIM90438.1 - 0.044 13.7 0.0 0.56 10.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) ADH_zinc_N_2 PF13602.6 EIM90439.1 - 1e-18 68.7 0.0 2.6e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EIM90439.1 - 2.1e-13 50.4 0.1 3.7e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM90439.1 - 0.091 12.7 0.0 1.9 8.4 0.0 2.5 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain Spc24 PF08286.11 EIM90440.1 - 8.6e-21 74.2 0.6 3e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APH_6_hur PF04655.14 EIM90440.1 - 0.0025 17.2 0.6 0.0025 17.2 0.6 1.6 2 0 0 2 2 2 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APG6_N PF17675.1 EIM90440.1 - 0.064 13.8 7.7 0.094 13.2 7.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 EIM90440.1 - 0.11 13.2 5.0 3.1 8.5 0.7 2.3 2 0 0 2 2 2 0 SlyX DUF3510 PF12022.8 EIM90440.1 - 0.17 12.3 2.4 1.5 9.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) OmpH PF03938.14 EIM90440.1 - 0.21 11.9 8.8 0.65 10.3 8.8 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 EIM90440.1 - 0.26 9.8 1.8 0.37 9.3 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 EIM90440.1 - 0.27 11.4 1.0 0.41 10.8 1.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 EIM90440.1 - 0.47 10.5 9.5 0.076 13.0 2.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding T2SSM PF04612.12 EIM90440.1 - 1.8 8.6 9.7 6.9 6.7 1.7 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M TMF_TATA_bd PF12325.8 EIM90440.1 - 4.4 7.6 9.4 0.63 10.3 1.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EIM90440.1 - 4.8 7.0 10.0 14 5.5 3.3 2.2 2 0 0 2 2 2 0 Septum formation initiator TPT PF03151.16 EIM90443.1 - 3.5e-10 39.7 2.3 5.4e-05 22.7 0.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EIM90443.1 - 8.8e-10 38.9 30.0 4.4e-06 26.9 3.3 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EIM90443.1 - 4.3e-07 29.4 5.3 7.4e-07 28.7 5.3 1.3 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EIM90443.1 - 1.6e-06 27.5 0.3 1.6e-06 27.5 0.3 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter CBP4 PF07960.11 EIM90445.1 - 3.3e-10 39.9 0.0 3.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 CBP4 F-box-like PF12937.7 EIM90446.1 - 6.9e-08 32.3 0.2 3.5e-07 30.0 0.2 2.3 1 0 0 1 1 1 1 F-box-like adh_short PF00106.25 EIM90447.1 - 9.8e-41 139.4 0.5 1.3e-40 139.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90447.1 - 4.5e-24 85.3 0.5 5.7e-24 85.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM90447.1 - 0.00014 21.8 0.4 0.0003 20.7 0.4 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EIM90447.1 - 0.0022 17.9 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 EIM90447.1 - 0.02 14.7 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EIM90447.1 - 0.035 13.6 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EIM90447.1 - 0.037 14.6 0.0 0.093 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EIM90447.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Hexapep_loop PF18776.1 EIM90447.1 - 1 9.0 4.4 0.25 11.0 0.9 1.8 2 0 0 2 2 2 0 Hexapeptide repeat including loop Alginate_lyase PF05426.12 EIM90448.1 - 5.8e-15 55.6 9.6 1.6e-14 54.2 9.6 1.5 1 1 0 1 1 1 1 Alginate lyase UQ_con PF00179.26 EIM90449.1 - 4.5e-15 55.5 0.0 7.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rubredoxin PF00301.20 EIM90449.1 - 0.092 12.8 1.7 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin Transcrip_reg PF01709.20 EIM90450.1 - 9.5e-70 234.7 1.3 1.1e-69 234.5 1.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator THUMP PF02926.17 EIM90450.1 - 0.026 14.6 0.6 0.27 11.3 0.7 2.2 1 1 0 1 1 1 0 THUMP domain ABC_membrane PF00664.23 EIM90451.1 - 6.4e-53 180.2 34.8 2.6e-27 96.2 14.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM90451.1 - 1.5e-51 174.5 0.0 5.9e-28 98.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM90451.1 - 7e-08 32.2 0.5 0.0046 16.4 0.2 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EIM90451.1 - 9.3e-06 25.7 1.4 0.059 13.4 0.2 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EIM90451.1 - 1e-05 25.1 1.3 0.12 12.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EIM90451.1 - 1.7e-05 24.5 0.1 0.19 11.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EIM90451.1 - 4.9e-05 23.8 3.6 2.1 8.7 0.1 3.7 2 2 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM90451.1 - 0.00048 20.1 1.9 0.22 11.4 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EIM90451.1 - 0.00061 20.3 2.8 4.6 7.7 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_21 PF13304.6 EIM90451.1 - 0.0026 17.6 8.4 0.54 10.0 0.0 4.0 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 EIM90451.1 - 0.0041 16.9 0.8 0.77 9.5 0.1 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EIM90451.1 - 0.014 15.7 3.6 2.5 8.4 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIM90451.1 - 0.022 14.5 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EIM90451.1 - 0.025 14.2 1.0 1.2 8.7 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EIM90451.1 - 0.042 13.6 3.0 5.4 6.7 0.5 3.1 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EIM90451.1 - 0.059 13.3 0.8 2.6 7.9 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 EIM90451.1 - 0.072 12.8 2.2 2.1 8.0 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 EIM90451.1 - 0.077 13.2 1.0 5.1 7.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EIM90451.1 - 0.088 12.9 2.2 0.69 10.0 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 EIM90451.1 - 0.1 12.8 0.1 29 4.9 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EIM90451.1 - 0.11 12.0 1.0 7.4 6.0 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EIM90451.1 - 0.13 12.2 0.2 11 6.0 0.0 3.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EIM90451.1 - 0.25 10.5 1.5 13 4.9 0.5 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 EIM90451.1 - 0.65 10.0 6.6 3.8 7.5 0.1 2.8 3 0 0 3 3 3 0 Dynamin family ABC_ATPase PF09818.9 EIM90451.1 - 2.2 7.0 5.0 9.2 4.9 0.0 3.4 4 0 0 4 4 4 0 Predicted ATPase of the ABC class WD40 PF00400.32 EIM90453.1 - 1.2e-25 89.2 14.2 6.4e-09 36.3 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90453.1 - 1.7e-07 31.4 0.0 0.013 15.8 0.0 3.8 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM90453.1 - 0.0039 16.2 0.0 0.2 10.6 0.0 3.1 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_D_N PF18018.1 EIM90454.1 - 8.1e-41 139.2 0.0 1.3e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EIM90454.1 - 5.1e-33 114.2 0.2 1.3e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Copper-bind PF00127.20 EIM90455.1 - 0.0019 18.6 0.0 0.0047 17.3 0.0 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Hid1 PF12722.7 EIM90456.1 - 3.5e-179 597.7 0.0 4.3e-179 597.4 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EIM90456.1 - 2.2e-87 294.0 0.0 2.8e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 EIM90456.1 - 0.079 11.9 0.1 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF3391 PF11871.8 EIM90457.1 - 0.063 13.8 0.5 0.59 10.7 0.0 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3391) Guanylin PF02058.15 EIM90459.1 - 0.05 14.1 0.0 0.074 13.5 0.0 1.3 1 0 0 1 1 1 0 Guanylin precursor YhcG_C PF06250.11 EIM90459.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain Phage_integrase PF00589.22 EIM90460.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Phage integrase family RVT_1 PF00078.27 EIM90461.1 - 2.7e-10 40.1 0.0 1.1e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_4 PF06347.13 EIM90461.1 - 0.39 10.6 0.1 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Bacterial SH3 domain RNase_H PF00075.24 EIM90462.1 - 1.1e-24 87.3 0.0 1.2e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 RNase H Rad51 PF08423.11 EIM90463.1 - 3.8e-10 39.5 0.2 4.9e-10 39.1 0.2 1.1 1 0 0 1 1 1 1 Rad51 Atg8 PF02991.16 EIM90464.1 - 1.4e-51 173.0 0.2 1.6e-51 172.8 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EIM90464.1 - 5.5e-07 29.9 0.0 6.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.17 EIM90464.1 - 0.044 13.5 0.0 0.083 12.6 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain BRE1 PF08647.11 EIM90465.1 - 0.0015 18.6 2.1 0.0024 17.9 2.1 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase BBS2_C PF14782.6 EIM90465.1 - 0.006 15.4 0.1 0.0081 15.0 0.1 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal CCD48 PF15799.5 EIM90465.1 - 0.011 14.1 0.9 0.014 13.7 0.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF5320 PF17253.2 EIM90465.1 - 0.69 11.0 3.7 0.23 12.5 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) UCR_14kD PF02271.16 EIM90466.1 - 7.5e-41 138.2 0.3 8.7e-41 138.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NDK PF00334.19 EIM90467.1 - 3.4e-54 182.5 0.0 3.8e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pkinase_Tyr PF07714.17 EIM90468.1 - 6.2e-37 127.3 0.0 1e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.19 EIM90468.1 - 1.1e-32 113.7 0.7 2.1e-32 112.7 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain Pkinase PF00069.25 EIM90468.1 - 1.3e-30 106.7 0.0 2.4e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RasGEF_N PF00618.20 EIM90468.1 - 6.7e-10 39.2 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif APH PF01636.23 EIM90468.1 - 0.028 14.4 0.3 0.028 14.4 0.3 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cmc1 PF08583.10 EIM90469.1 - 4.2e-10 39.5 1.7 4.9e-10 39.3 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EIM90469.1 - 0.0088 16.0 0.7 0.015 15.3 0.7 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 EIM90469.1 - 0.0097 15.6 0.5 0.019 14.7 0.5 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) B56 PF01603.20 EIM90469.1 - 0.086 11.8 0.7 0.097 11.6 0.7 1.0 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Transketolase_N PF00456.21 EIM90470.1 - 6.6e-155 515.1 0.1 9e-155 514.7 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EIM90470.1 - 1.2e-42 145.6 0.0 3.9e-42 143.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIM90470.1 - 8.1e-15 54.8 0.0 1.6e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EIM90470.1 - 4.1e-06 26.2 0.0 1e-05 24.9 0.0 1.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase AAA_19 PF13245.6 EIM90471.1 - 5.6e-10 39.7 0.0 1.7e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EIM90471.1 - 4.5e-09 36.2 0.0 0.00099 18.7 0.0 2.6 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EIM90471.1 - 1.6e-06 27.8 0.0 4.5e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EIM90471.1 - 4.1e-05 23.1 0.0 8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 EIM90471.1 - 7.7e-05 22.4 0.0 0.00034 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM90471.1 - 0.00025 20.8 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EIM90471.1 - 0.0011 18.8 0.2 0.29 10.8 0.0 3.3 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EIM90471.1 - 0.0021 17.4 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 EIM90471.1 - 0.07 12.5 0.6 0.15 11.4 0.1 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DEAD PF00270.29 EIM90471.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 EIM90471.1 - 0.16 11.3 0.6 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin MFS_1 PF07690.16 EIM90472.1 - 1.1e-33 116.6 36.7 1.1e-33 116.6 36.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 EIM90473.1 - 3.6e-46 154.2 27.8 1.3e-08 35.4 0.3 9.1 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EIM90473.1 - 1.3e-11 44.2 0.2 3.1e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM90473.1 - 2e-10 40.3 0.2 4.8e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EIM90473.1 - 7e-10 38.2 11.3 0.34 9.5 0.0 6.2 2 2 3 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EIM90473.1 - 2.3e-09 37.4 0.6 1.4 9.2 0.1 5.5 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EIM90473.1 - 0.00075 19.4 0.0 0.0053 16.6 0.0 2.4 3 0 0 3 3 3 1 F-box BRK PF07533.16 EIM90473.1 - 0.023 14.3 0.3 54 3.5 0.0 4.0 4 0 0 4 4 4 0 BRK domain Pkinase PF00069.25 EIM90475.1 - 2.2e-64 217.4 0.0 2.6e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90475.1 - 1.3e-25 90.1 0.0 1.8e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM90475.1 - 0.00016 21.1 0.0 0.001 18.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EIM90475.1 - 0.00034 20.6 0.1 0.033 14.1 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM90475.1 - 0.047 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EIM90475.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIM90475.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2TM PF13239.6 EIM90478.1 - 4.1 7.8 5.3 1.8 8.9 2.0 2.0 1 1 1 2 2 2 0 2TM domain Glyco_hydro_63 PF03200.16 EIM90479.1 - 1.8e-157 525.1 0.1 1.9e-156 521.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EIM90479.1 - 3.6e-71 239.9 0.0 1.9e-70 237.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EIM90479.1 - 0.00086 18.3 0.1 0.0015 17.5 0.1 1.3 1 0 0 1 1 1 1 Trehalase RNB PF00773.19 EIM90480.1 - 3.6e-95 319.1 0.0 5.1e-95 318.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EIM90480.1 - 3.8e-27 94.8 0.0 1e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EIM90480.1 - 3.3e-25 87.9 1.9 6.9e-25 86.8 1.9 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EIM90480.1 - 2.9e-15 56.0 0.0 1.5e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EIM90480.1 - 8.8e-10 39.0 0.0 2.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EIM90480.1 - 1.7e-06 28.1 4.3 0.00085 19.4 0.0 4.5 5 0 0 5 5 5 1 Cold shock domain OB_RNB PF08206.11 EIM90480.1 - 0.36 10.5 2.1 1.9 8.2 0.1 2.8 3 0 0 3 3 3 0 Ribonuclease B OB domain HAD_2 PF13419.6 EIM90481.1 - 2.6e-09 37.4 0.0 3.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM90481.1 - 1.9e-07 31.6 0.0 5.2e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM90481.1 - 6.5e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Phage_holin_2_2 PF10746.9 EIM90481.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II Pyridoxal_deC PF00282.19 EIM90482.1 - 2e-62 211.1 0.0 2.7e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EIM90482.1 - 7.1e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DNA_pol_A_exo1 PF01612.20 EIM90483.1 - 1.2e-06 28.3 0.0 2.8e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease MAGE PF01454.19 EIM90483.1 - 0.082 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 MAGE family DNA_pol_A_exo1 PF01612.20 EIM90484.1 - 1.4e-07 31.4 0.0 2.6e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease adh_short_C2 PF13561.6 EIM90485.1 - 2.5e-51 174.5 0.0 3.1e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM90485.1 - 7.6e-35 120.1 0.1 1e-34 119.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM90485.1 - 1.2e-09 38.3 0.1 1.8e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_24 PF13578.6 EIM90485.1 - 0.098 13.7 0.0 0.19 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PIN_4 PF13638.6 EIM90486.1 - 1.7e-19 70.4 0.1 4.4e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 EIM90486.1 - 2.5e-10 40.3 0.0 4.3e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain Pet100 PF09803.9 EIM90487.1 - 1.5e-25 89.4 0.2 1.9e-25 89.1 0.2 1.1 1 0 0 1 1 1 1 Pet100 DUF4227 PF14004.6 EIM90487.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) peroxidase PF00141.23 EIM90488.1 - 3e-21 76.2 0.0 4.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Big_3_5 PF16640.5 EIM90488.1 - 0.07 13.3 11.0 0.29 11.4 0.1 3.9 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 3) BTP PF05232.12 EIM90488.1 - 0.25 11.4 0.7 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 Chlorhexidine efflux transporter DNA_pol_A_exo1 PF01612.20 EIM90489.1 - 4.9e-07 29.6 0.0 8.7e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease MAGE PF01454.19 EIM90489.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 MAGE family OTT_1508_deam PF14441.6 EIM90490.1 - 1.9e-08 34.2 4.0 2.1e-08 34.0 2.6 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase SopA PF13981.6 EIM90490.1 - 0.0013 19.1 0.1 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 SopA-like central domain DUF5602 PF18197.1 EIM90490.1 - 0.24 11.9 0.9 4.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5602) PALP PF00291.25 EIM90491.1 - 7.4e-57 193.0 0.0 8.8e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cyt-b5 PF00173.28 EIM90492.1 - 9.4e-21 73.8 1.2 1.6e-20 73.0 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EIM90492.1 - 5.8e-12 46.1 15.8 5.8e-12 46.1 15.8 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Amidohydro_2 PF04909.14 EIM90495.1 - 5.1e-17 62.6 0.0 9.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EIM90495.1 - 0.0071 15.8 0.0 0.036 13.4 0.0 2.0 2 1 0 2 2 2 1 TatD related DNase CNDH2_C PF16858.5 EIM90495.1 - 0.028 14.3 0.0 4.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BolA PF01722.18 EIM90496.1 - 6.7e-19 67.9 0.2 1.4e-18 66.9 0.2 1.5 1 1 0 1 1 1 1 BolA-like protein Glyco_hydro_31 PF01055.26 EIM90498.1 - 8.9e-113 377.8 0.2 1.2e-112 377.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EIM90498.1 - 1e-15 57.8 0.1 2.8e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like WD40 PF00400.32 EIM90499.1 - 9.6e-21 73.7 4.1 3.3e-06 27.7 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90499.1 - 1.8e-05 24.9 0.1 4.7 7.6 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleo_P87 PF07267.11 EIM90499.1 - 0.2 10.5 2.6 0.3 9.9 2.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 EIM90499.1 - 0.51 9.6 13.0 0.7 9.2 13.0 1.2 1 0 0 1 1 1 0 NOA36 protein PBP_sp32 PF07222.12 EIM90499.1 - 7.9 5.9 7.9 14 5.1 7.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PPP4R2 PF09184.11 EIM90499.1 - 8.3 5.9 15.7 0.56 9.8 11.1 1.4 2 0 0 2 2 2 0 PPP4R2 BEN PF10523.9 EIM90500.1 - 0.22 11.8 0.0 0.67 10.2 0.0 1.7 2 0 0 2 2 2 0 BEN domain MRP-L27 PF09809.9 EIM90501.1 - 5.3e-11 42.4 0.4 7.2e-11 41.9 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 AAA_22 PF13401.6 EIM90503.1 - 0.0062 16.8 0.3 5.8 7.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain F-box-like PF12937.7 EIM90506.1 - 2.3e-07 30.6 0.3 8.6e-07 28.7 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM90506.1 - 0.032 14.1 1.4 0.13 12.2 0.2 2.6 2 0 0 2 2 2 0 F-box domain CBF PF03914.17 EIM90507.1 - 9.7e-33 113.6 5.5 7.2e-32 110.8 1.6 2.6 2 1 0 2 2 2 2 CBF/Mak21 family HEAT PF02985.22 EIM90507.1 - 0.1 12.9 0.0 14 6.3 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat COQ7 PF03232.13 EIM90509.1 - 6.8e-70 234.3 0.4 8.1e-70 234.0 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NDUF_B4 PF07225.12 EIM90510.1 - 0.0035 17.2 0.0 0.0037 17.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.23 EIM90511.1 - 1.7e-13 50.2 2.1 4.4e-13 48.9 2.1 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EIM90511.1 - 8.6e-11 41.5 0.1 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EIM90511.1 - 1.3e-05 25.2 0.5 4.3e-05 23.5 0.5 2.0 1 0 0 1 1 1 1 G-patch domain PHM7_cyt PF14703.6 EIM90511.1 - 0.0022 18.3 0.1 2.1 8.6 0.0 2.8 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter zf-C2H2_jaz PF12171.8 EIM90511.1 - 0.0042 17.3 1.5 0.0042 17.3 1.5 1.7 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding ROS_MUCR PF05443.11 EIM90511.1 - 0.017 15.1 0.2 0.044 13.8 0.2 1.7 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein RED_N PF07808.13 EIM90511.1 - 0.048 13.2 0.3 0.048 13.2 0.3 2.0 2 1 0 2 2 2 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 EIM90511.1 - 0.051 13.9 0.2 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 EIM90511.1 - 0.13 12.0 0.3 0.25 11.0 0.3 1.3 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 EIM90511.1 - 0.17 12.8 0.5 0.38 11.7 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EIM90511.1 - 0.19 12.2 0.5 0.39 11.3 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM90512.1 - 0.0011 19.6 7.7 0.081 13.8 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EIM90512.1 - 0.0095 16.3 3.0 0.59 10.7 0.2 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM90512.1 - 0.68 10.5 3.0 0.89 10.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double domain FH2 PF02181.23 EIM90513.1 - 3.3e-78 263.4 2.1 3.3e-78 263.4 2.1 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EIM90513.1 - 6.6e-35 120.4 0.0 1.8e-34 118.9 0.0 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EIM90513.1 - 5.1e-32 111.1 2.5 5.3e-32 111.0 0.4 2.1 2 0 0 2 2 2 1 Diaphanous FH3 Domain CC2-LZ PF16516.5 EIM90513.1 - 0.28 11.6 7.0 0.1 13.0 1.9 3.0 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HTH_32 PF13565.6 EIM90513.1 - 2.5 8.8 4.8 31 5.3 0.1 4.5 4 0 0 4 4 4 0 Homeodomain-like domain F-box-like PF12937.7 EIM90514.1 - 3e-06 27.0 6.0 3e-06 27.0 6.0 3.1 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EIM90514.1 - 0.0042 17.5 0.2 5.2 7.6 0.0 4.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) PAP2 PF01569.21 EIM90515.1 - 6.2e-25 87.5 3.5 6.2e-25 87.5 3.5 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF4229 PF14012.6 EIM90515.1 - 0.19 11.8 4.0 1.4 9.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) CRM1_C PF08767.11 EIM90517.1 - 8.3e-102 340.6 5.9 1.1e-99 333.7 0.1 3.9 4 0 0 4 4 4 2 CRM1 C terminal Xpo1 PF08389.12 EIM90517.1 - 1.2e-35 122.8 10.9 2.3e-35 121.8 4.7 4.1 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EIM90517.1 - 8.4e-31 105.4 1.6 2.4e-30 104.0 1.6 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EIM90517.1 - 4.3e-26 90.8 5.4 1.8e-25 88.8 1.8 3.2 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EIM90517.1 - 6e-16 57.7 0.1 1.4e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EIM90517.1 - 1.4e-11 44.2 0.1 1.8e-10 40.6 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EIM90517.1 - 0.0014 18.6 0.0 0.065 13.1 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Med10 PF09748.9 EIM90518.1 - 3.9e-20 72.0 0.0 4.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex FUSC_2 PF13515.6 EIM90519.1 - 2.4e-15 56.8 15.1 2.4e-15 56.8 15.1 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EIM90519.1 - 1.2e-10 40.6 2.3 3e-10 39.3 2.3 1.7 1 0 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.8 EIM90519.1 - 0.016 14.1 16.3 0.018 13.9 12.4 2.6 2 1 0 2 2 2 0 Aluminium activated malate transporter ArAE_2_N PF10337.9 EIM90519.1 - 0.12 11.4 11.3 0.63 9.0 0.1 3.8 4 0 0 4 4 4 0 Putative ER transporter, 6TM, N-terminal Prominin PF05478.11 EIM90519.1 - 0.22 9.5 0.7 0.35 8.8 0.7 1.2 1 0 0 1 1 1 0 Prominin ArAE_1 PF06081.11 EIM90519.1 - 4.2 7.5 16.4 0.11 12.6 8.1 2.5 2 1 0 2 2 2 0 Aromatic acid exporter family member 1 Myosin_head PF00063.21 EIM90520.1 - 1.1e-256 853.4 0.0 1.9e-256 852.6 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EIM90520.1 - 4.4e-26 91.2 1.8 4.4e-26 91.2 1.8 3.2 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 EIM90520.1 - 5.1e-14 50.7 36.3 0.0017 18.0 1.6 7.1 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.6 EIM90520.1 - 0.0095 16.2 0.2 0.096 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.19 EIM90520.1 - 0.026 14.3 0.7 0.057 13.3 0.7 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain NACHT PF05729.12 EIM90520.1 - 0.043 13.7 0.7 2 8.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EIM90520.1 - 0.13 12.8 2.4 1.2 9.7 0.0 2.9 2 0 0 2 2 2 0 ABC transporter KASH_CCD PF14662.6 EIM90520.1 - 0.29 10.9 27.4 2.7 7.8 22.3 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH AAA_16 PF13191.6 EIM90520.1 - 0.49 10.8 0.0 0.49 10.8 0.0 3.0 2 1 0 2 2 1 0 AAA ATPase domain Atg14 PF10186.9 EIM90520.1 - 4.6 6.2 16.2 11 5.0 16.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EIM90520.1 - 7.8 6.6 20.8 2.5 8.2 4.1 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-AN1 PF01428.16 EIM90521.1 - 2.1e-17 63.0 17.5 2e-10 40.6 6.0 2.5 2 1 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EIM90521.1 - 7.8 6.8 13.7 0.077 13.2 2.5 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Gpi1 PF05024.15 EIM90522.1 - 1.5e-54 185.0 9.6 2.4e-54 184.3 9.6 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Snf7 PF03357.21 EIM90523.1 - 2.5e-40 137.9 20.3 2.5e-40 137.9 20.3 1.7 2 0 0 2 2 2 1 Snf7 Tub_N PF16322.5 EIM90523.1 - 0.033 14.6 1.1 0.043 14.2 1.1 1.2 1 0 0 1 1 1 0 Tubby N-terminal Resolvase PF00239.21 EIM90523.1 - 0.16 12.1 11.0 0.091 12.9 4.4 2.5 1 1 1 2 2 2 0 Resolvase, N terminal domain YlqD PF11068.8 EIM90523.1 - 2.4 8.5 15.4 9 6.7 4.1 2.1 1 1 1 2 2 2 0 YlqD protein COG4 PF08318.12 EIM90524.1 - 3.8e-91 305.7 0.0 7e-91 304.8 0.0 1.5 1 0 0 1 1 1 1 COG4 transport protein JIP_LZII PF16471.5 EIM90524.1 - 0.05 13.8 0.1 0.22 11.7 0.0 2.1 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II RINT1_TIP1 PF04437.13 EIM90524.1 - 0.11 11.3 0.1 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 RINT-1 / TIP-1 family Cellulase PF00150.18 EIM90525.1 - 6.7e-14 52.0 0.5 2.3e-13 50.2 0.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Epimerase PF01370.21 EIM90526.1 - 2.4e-16 59.9 0.0 2.5e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM90526.1 - 2.7e-09 36.9 0.0 4.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM90526.1 - 1.9e-06 27.2 0.0 6e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EIM90526.1 - 5.3e-06 25.6 0.0 1.5e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EIM90526.1 - 0.038 13.5 0.2 0.29 10.6 0.0 2.2 3 0 0 3 3 3 0 short chain dehydrogenase NmrA PF05368.13 EIM90526.1 - 0.05 13.1 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Pkinase PF00069.25 EIM90527.1 - 4.3e-53 180.3 0.1 6e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90527.1 - 2.9e-19 69.4 0.2 5.4e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM90527.1 - 0.0033 17.4 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM90527.1 - 0.0037 16.9 1.0 0.0078 15.8 1.0 1.5 1 0 0 1 1 1 1 RIO1 family ABC1 PF03109.16 EIM90527.1 - 0.1 12.8 0.1 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 ABC1 family Choline_kinase PF01633.20 EIM90527.1 - 0.24 11.0 1.4 0.44 10.1 1.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DEAD PF00270.29 EIM90529.1 - 2.1e-23 83.0 0.0 6.1e-23 81.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM90529.1 - 3.1e-19 69.3 0.0 1.9e-17 63.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EIM90529.1 - 3.9e-11 43.5 3.0 3.9e-11 43.5 3.0 2.0 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 EIM90529.1 - 3.8e-08 33.1 0.0 7.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 EIM90529.1 - 2.3e-05 24.5 0.0 5.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EIM90529.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain DUF4566 PF15130.6 EIM90529.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) AAA_22 PF13401.6 EIM90529.1 - 0.068 13.4 0.2 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 EIM90529.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DEAD PF00270.29 EIM90530.1 - 1.8e-44 151.6 0.0 5.8e-44 150.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM90530.1 - 1e-26 93.5 0.0 5.5e-26 91.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM90530.1 - 1.1e-06 28.7 0.2 0.00013 22.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_DrpA PF18255.1 EIM90530.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain SBF_like PF13593.6 EIM90530.1 - 0.15 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) CMS1 PF14617.6 EIM90530.1 - 0.22 10.8 7.3 0.91 8.8 0.0 2.6 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit GalP_UDP_transf PF01087.22 EIM90531.1 - 4.2e-60 203.3 0.0 9.8e-60 202.1 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EIM90531.1 - 1.9e-49 167.6 0.0 1.8e-48 164.4 0.0 2.2 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EIM90531.1 - 0.0023 18.6 0.6 0.011 16.4 0.1 2.3 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EIM90531.1 - 0.016 15.7 0.1 0.042 14.3 0.1 1.7 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding 6PF2K PF01591.18 EIM90533.1 - 1.2e-67 227.6 0.1 1.5e-67 227.1 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EIM90533.1 - 7.6e-37 126.9 0.0 1.4e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EIM90533.1 - 1.3e-06 28.6 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EIM90533.1 - 0.0029 18.0 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIM90533.1 - 0.026 14.0 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rsa3 PF14615.6 EIM90533.1 - 0.039 13.5 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Glyco_transf_8 PF01501.20 EIM90534.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF616 PF04765.13 EIM90534.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF616) PNK3P PF08645.11 EIM90535.1 - 2.1e-45 154.4 0.0 3.3e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EIM90535.1 - 2.8e-19 69.7 0.0 9.4e-09 35.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain LNS2 PF08235.13 EIM90535.1 - 0.0011 18.6 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Hydrolase_6 PF13344.6 EIM90535.1 - 0.012 15.7 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MMR_HSR1 PF01926.23 EIM90535.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase KTI12 PF08433.10 EIM90535.1 - 0.14 11.6 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sel1 PF08238.12 EIM90536.1 - 3.3e-49 164.2 22.7 1.2e-09 38.5 0.0 7.7 7 0 0 7 7 7 7 Sel1 repeat JHD PF17811.1 EIM90537.1 - 4.5e-10 40.0 0.0 9.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 EIM90537.1 - 1.5e-07 31.8 0.2 2.3e-06 28.0 0.2 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EIM90537.1 - 2.4e-07 30.5 9.0 4.5e-07 29.6 9.0 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 EIM90537.1 - 7.1e-05 22.6 0.1 0.00087 19.1 0.0 2.7 2 2 0 2 2 2 1 Cupin-like domain zf-RING_9 PF13901.6 EIM90537.1 - 0.21 11.5 2.5 0.51 10.3 2.5 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon UPF1_Zn_bind PF09416.10 EIM90537.1 - 0.27 11.2 3.1 2.8 7.9 0.0 2.6 1 1 1 2 2 2 0 RNA helicase (UPF2 interacting domain) zf-CW PF07496.15 EIM90537.1 - 0.36 10.9 8.4 1.1 9.3 8.4 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 EIM90537.1 - 2.9 7.5 4.8 5.8 6.6 4.8 1.5 1 0 0 1 1 1 0 PHD-finger Ras PF00071.22 EIM90538.1 - 7.5e-53 178.4 0.0 8.9e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM90538.1 - 3.7e-22 78.8 0.0 5.6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM90538.1 - 6.2e-07 29.0 0.0 1.5e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EIM90538.1 - 0.0017 18.3 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EIM90538.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIM90538.1 - 0.094 12.2 0.0 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EIM90538.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Atg14 PF10186.9 EIM90539.1 - 0.71 8.9 11.3 0.92 8.5 11.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4061 PF13270.6 EIM90539.1 - 3.2 8.1 14.2 1.2 9.5 11.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) V_ATPase_I PF01496.19 EIM90539.1 - 5.3 4.8 5.0 6.4 4.6 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PGK PF00162.19 EIM90540.1 - 6.8e-147 489.3 0.1 7.7e-147 489.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Ytca PF17090.5 EIM90541.1 - 0.036 14.6 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family DDE_3 PF13358.6 EIM90545.1 - 2.1e-07 30.8 1.5 6.9e-07 29.1 0.4 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease CxC6 PF18721.1 EIM90547.1 - 6.3e-19 68.0 5.6 7.3e-19 67.8 5.6 1.1 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases HTH_Tnp_Tc5 PF03221.16 EIM90549.1 - 2.6e-05 24.2 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 EIM90550.1 - 7.2e-15 55.1 0.0 3.1e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIM90550.1 - 1.3e-05 25.0 0.0 0.00071 19.4 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Helicase_C PF00271.31 EIM90552.1 - 0.00048 20.5 0.0 0.00082 19.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Astro_capsid_p PF12226.8 EIM90552.1 - 0.72 8.9 7.1 0.82 8.8 7.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 EIM90552.1 - 2.8 6.0 14.4 3.1 5.9 14.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EIM90552.1 - 5.5 5.2 11.3 5.9 5.1 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein CHORD PF04968.12 EIM90554.1 - 1.8e-47 159.9 14.7 2.3e-24 85.9 5.3 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 EIM90554.1 - 5.7e-14 52.9 0.0 1e-13 52.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Rieske PF00355.26 EIM90554.1 - 0.025 14.5 4.2 2.1 8.3 0.5 2.4 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain BTK PF00779.19 EIM90554.1 - 8.1 6.4 13.0 8.9 6.2 0.3 3.3 3 1 0 3 3 3 0 BTK motif Cu-oxidase_3 PF07732.15 EIM90555.1 - 7.6e-40 135.6 1.9 7.6e-40 135.6 1.9 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM90555.1 - 4.4e-36 123.6 4.7 2.8e-30 104.9 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EIM90555.1 - 5.8e-33 114.3 0.1 1.6e-32 112.8 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Chitin_synth_2 PF03142.15 EIM90557.1 - 2.7e-10 39.5 0.0 6e-08 31.7 0.0 2.9 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 EIM90557.1 - 2.9e-09 37.2 0.2 7.2e-06 26.1 0.3 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EIM90557.1 - 4.6e-07 29.9 4.9 4.6e-07 29.9 4.9 2.9 1 1 2 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EIM90557.1 - 0.0093 15.5 0.3 0.023 14.2 0.3 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EIM90557.1 - 0.011 15.6 0.0 0.81 9.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DDDD PF10161.9 EIM90558.1 - 0.18 11.6 0.2 7.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Uricase PF01014.18 EIM90560.1 - 3.2e-66 221.5 0.9 3.3e-37 127.7 1.1 2.1 2 0 0 2 2 2 2 Uricase ATP-synt_G PF04718.15 EIM90561.1 - 5.3e-17 62.5 2.5 1.2e-16 61.4 0.1 2.1 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit YtxH PF12732.7 EIM90561.1 - 0.033 14.7 0.4 0.053 14.0 0.4 1.3 1 0 0 1 1 1 0 YtxH-like protein V-ATPase_G_2 PF16999.5 EIM90561.1 - 0.2 12.1 6.9 0.34 11.3 6.9 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit HisKA_3 PF07730.13 EIM90561.1 - 0.33 11.5 2.1 8.9 6.9 0.9 2.7 1 1 1 2 2 2 0 Histidine kinase Apo-CIII PF05778.12 EIM90561.1 - 0.46 10.2 2.3 3.3 7.4 0.8 2.5 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) ATP-synt_B PF00430.18 EIM90561.1 - 1.2 9.2 10.4 1.4 9.0 9.1 1.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Ifi-6-16 PF06140.13 EIM90562.1 - 4.6e-05 23.2 2.0 0.0001 22.1 2.0 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF4400 PF14348.6 EIM90562.1 - 0.9 9.0 7.8 0.086 12.3 1.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4400) Ifi-6-16 PF06140.13 EIM90563.1 - 0.0089 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family FAD_binding_3 PF01494.19 EIM90564.1 - 2.6e-70 237.4 0.0 3.2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM90564.1 - 0.0002 20.7 0.1 0.00085 18.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM90564.1 - 0.0043 15.8 0.1 0.66 8.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EIM90564.1 - 0.006 16.2 0.3 1 8.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM90564.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM90564.1 - 0.099 11.7 0.1 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EIM90564.1 - 0.11 13.0 0.1 6.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 EIM90565.1 - 2.6e-42 144.5 0.0 3.8e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90565.1 - 7.3e-30 104.2 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM90565.1 - 6.2e-10 39.3 0.0 1.2e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EIM90565.1 - 0.00031 19.9 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EIM90565.1 - 0.0041 16.6 0.0 0.018 14.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2202 PF09968.9 EIM90566.1 - 0.0058 16.5 0.1 0.0083 16.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein domain (DUF2202) adh_short PF00106.25 EIM90567.1 - 1.9e-38 131.9 0.0 3.1e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90567.1 - 1.1e-25 90.5 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM90567.1 - 2e-09 37.6 0.0 8.1e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM90567.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EIM90567.1 - 0.055 12.5 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain DUF5108 PF17133.4 EIM90568.1 - 0.0084 16.1 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5108) RSN1_7TM PF02714.15 EIM90568.1 - 0.17 11.2 0.6 0.57 9.4 0.1 1.9 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate zf-H2C2_2 PF13465.6 EIM90569.1 - 2.7e-08 33.8 8.8 1.2e-06 28.7 1.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EIM90569.1 - 2e-06 28.0 15.7 0.0038 17.6 4.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 EIM90569.1 - 0.001 19.4 1.0 0.0024 18.2 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EIM90569.1 - 0.0056 17.4 14.3 0.013 16.3 3.3 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM90569.1 - 0.25 11.7 3.5 2.8 8.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Apt1 PF10351.9 EIM90569.1 - 0.28 10.0 2.8 0.4 9.5 2.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zn_clus PF00172.18 EIM90569.1 - 0.31 11.2 17.7 0.019 15.1 12.4 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_11 PF16622.5 EIM90569.1 - 1.4 8.7 8.9 0.73 9.6 2.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EIM90569.1 - 3.1 7.9 7.6 3.4 7.7 4.4 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 EIM90569.1 - 4 7.8 8.9 2.1 8.7 1.0 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) EutQ PF06249.12 EIM90571.1 - 3.1e-11 43.3 0.1 3.5e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EIM90571.1 - 3e-07 30.0 0.0 4.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EIM90571.1 - 0.0035 17.0 0.0 0.0082 15.8 0.0 1.7 1 1 1 2 2 2 1 Cupin domain Cupin_6 PF12852.7 EIM90571.1 - 0.062 13.0 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Cupin Pirin PF02678.16 EIM90571.1 - 0.091 12.7 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Pirin VWA_3 PF13768.6 EIM90572.1 - 2e-21 76.6 0.0 3.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EIM90572.1 - 3e-19 69.3 0.0 6.6e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EIM90572.1 - 5.3e-13 49.6 0.0 9.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EIM90572.1 - 3.6e-10 40.4 0.0 1.1e-09 38.9 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EIM90572.1 - 1.7e-06 27.6 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 EIM90572.1 - 6.2e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 EIM90572.1 - 0.0029 17.8 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Sec23_trunk PF04811.15 EIM90572.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Copine PF07002.16 EIM90572.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Copine CDPS PF16715.5 EIM90573.1 - 0.16 11.6 0.5 0.27 10.9 0.5 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase ADH_zinc_N PF00107.26 EIM90574.1 - 2.5e-13 50.1 0.0 4.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM90574.1 - 7.4e-08 32.2 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM90574.1 - 0.00018 22.6 0.0 0.0003 21.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Reo_sigmaC PF04582.12 EIM90575.1 - 0.024 14.9 0.1 0.083 13.2 0.0 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain NmrA PF05368.13 EIM90576.1 - 6e-24 84.9 0.6 1.3e-23 83.8 0.6 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90576.1 - 1.4e-13 51.1 1.6 5.6e-13 49.2 0.9 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EIM90576.1 - 3.6e-06 26.6 0.1 0.00021 20.8 0.1 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EIM90576.1 - 0.0013 19.0 0.2 0.0022 18.2 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 EIM90576.1 - 0.0017 18.3 0.1 0.0029 17.5 0.1 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EIM90576.1 - 0.025 15.1 0.8 0.043 14.4 0.8 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EIM90576.1 - 0.043 13.2 0.0 0.69 9.3 0.0 2.5 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIM90576.1 - 0.13 11.4 0.1 0.22 10.6 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 EIM90577.1 - 2.8e-69 234.0 0.0 2.1e-68 231.1 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 EIM90578.1 - 1.7e-57 194.7 0.2 2e-57 194.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM90578.1 - 3e-51 173.7 0.4 4.1e-51 173.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM90578.1 - 1e-06 28.8 0.2 1.6e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1205 PF06722.12 EIM90578.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) adh_short PF00106.25 EIM90579.1 - 2.8e-26 92.2 0.0 1.3e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90579.1 - 2.4e-17 63.3 0.0 9.1e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM90579.1 - 0.0035 17.3 0.1 0.0056 16.6 0.1 1.2 1 0 0 1 1 1 1 KR domain IclR PF01614.18 EIM90579.1 - 0.066 13.0 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial transcriptional regulator MFS_1 PF07690.16 EIM90581.1 - 9.8e-37 126.7 37.3 9.8e-37 126.7 37.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM90581.1 - 5.1e-07 28.9 25.2 1.2e-06 27.7 9.2 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3040 PF11239.8 EIM90581.1 - 0.13 12.6 6.9 0.15 12.4 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Glyco_hydro_18 PF00704.28 EIM90582.1 - 4.9e-13 49.5 0.0 6.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AMP-binding PF00501.28 EIM90583.1 - 5.6e-36 124.0 0.0 1.5e-35 122.6 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EIM90583.1 - 1.6e-05 24.7 4.8 0.00027 20.8 4.8 2.3 1 1 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EIM90583.1 - 0.052 14.5 0.2 0.099 13.6 0.2 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pex14_N PF04695.13 EIM90583.1 - 7.7 7.2 13.7 4.1 8.0 11.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NmrA PF05368.13 EIM90585.1 - 1e-22 80.9 0.5 3e-22 79.3 0.5 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90585.1 - 3.5e-14 53.1 0.4 1.8e-13 50.8 0.4 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM90585.1 - 7.3e-05 22.3 0.1 0.0036 16.8 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM90585.1 - 0.0013 18.2 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 EIM90585.1 - 0.0025 17.8 0.2 0.0039 17.1 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EIM90585.1 - 0.011 16.3 0.4 0.023 15.3 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ubie_methyltran PF01209.18 EIM90585.1 - 0.094 12.0 0.0 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DapB_N PF01113.20 EIM90585.1 - 0.1 12.7 0.2 0.24 11.5 0.2 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EIM90585.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-MYND PF01753.18 EIM90586.1 - 3.7e-10 39.7 11.4 7.5e-10 38.7 11.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM90586.1 - 0.15 12.4 7.1 0.4 11.0 7.1 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3494 PF11999.8 EIM90588.1 - 4.1e-56 189.9 13.3 4.8e-56 189.7 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) NmrA PF05368.13 EIM90589.1 - 3.3e-23 82.5 0.8 1.2e-22 80.6 0.8 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90589.1 - 2.8e-14 53.4 1.4 2.3e-13 50.4 1.4 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM90589.1 - 1.8e-06 27.6 0.1 0.0001 21.9 0.3 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM90589.1 - 0.00047 20.1 0.3 0.0013 18.6 0.2 1.8 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 EIM90589.1 - 0.0012 17.9 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM90589.1 - 0.0012 18.3 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EIM90589.1 - 0.0046 17.2 0.5 0.011 16.0 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EIM90589.1 - 0.0064 16.6 0.1 0.015 15.5 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Flagellar_rod PF05149.12 EIM90589.1 - 0.051 13.0 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein F420_oxidored PF03807.17 EIM90589.1 - 0.056 14.0 0.3 0.14 12.7 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_34 PF11312.8 EIM90589.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase VWA_3_C PF18571.1 EIM90589.1 - 0.26 11.2 2.1 0.39 10.6 0.5 2.1 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain NmrA PF05368.13 EIM90591.1 - 2.7e-21 76.2 0.1 9.2e-21 74.5 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90591.1 - 1.8e-15 57.3 0.1 2.3e-14 53.7 0.1 2.5 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EIM90591.1 - 0.0016 17.9 0.0 0.021 14.3 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM90591.1 - 0.013 15.4 0.1 0.068 13.1 0.0 2.0 2 1 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 EIM90591.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Apolipoprotein PF01442.18 EIM90592.1 - 0.021 14.7 11.8 0.065 13.1 2.7 3.6 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain C1_1 PF00130.22 EIM90592.1 - 1.2 9.0 11.9 0.49 10.3 4.8 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nbl1_Borealin_N PF10444.9 EIM90592.1 - 4.2 7.1 6.1 1.7 8.3 2.2 2.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Pkinase PF00069.25 EIM90593.1 - 9.2e-16 58.0 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90593.1 - 6.5e-07 28.9 0.0 9.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM90593.1 - 2.2e-05 23.4 0.0 2.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM90593.1 - 0.00016 21.7 0.2 0.00058 19.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM90593.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM90593.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EIM90594.1 - 2.6e-10 40.1 0.0 3.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Lipase_3 PF01764.25 EIM90596.1 - 2.5e-31 108.5 0.0 3.2e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EIM90596.1 - 0.0028 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 EIM90596.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 1 0 1 1 1 0 Cutinase DUF2048 PF09752.9 EIM90596.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 NmrA PF05368.13 EIM90597.1 - 1.3e-23 83.8 1.5 4e-23 82.2 1.5 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90597.1 - 2e-14 53.9 2.1 1.4e-13 51.2 2.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM90597.1 - 1.1e-06 28.3 0.2 7.7e-05 22.3 0.3 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM90597.1 - 0.00024 20.6 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 EIM90597.1 - 0.00032 20.7 0.5 0.00057 19.8 0.5 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EIM90597.1 - 0.002 17.2 0.2 0.0028 16.7 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EIM90597.1 - 0.027 15.1 0.5 0.077 13.6 0.5 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EIM90597.1 - 0.032 14.4 0.3 0.032 14.4 0.3 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EIM90597.1 - 0.052 14.0 0.7 0.13 12.7 0.4 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EIM90597.1 - 0.083 12.0 0.2 0.18 10.9 0.2 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 EIM90597.1 - 0.17 12.4 0.8 0.43 11.0 0.8 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Abhydrolase_3 PF07859.13 EIM90598.1 - 5.1e-42 144.1 0.0 6.6e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM90598.1 - 9.8e-07 28.0 0.1 3.4e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EIM90598.1 - 0.0039 16.1 0.1 0.0076 15.2 0.1 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 EIM90598.1 - 0.06 12.2 0.0 0.12 11.2 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EIM90598.1 - 0.12 11.6 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NmrA PF05368.13 EIM90599.1 - 9e-21 74.5 0.0 2.6e-20 73.0 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90599.1 - 2.7e-13 50.2 0.1 1.8e-12 47.5 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM90599.1 - 0.00056 19.5 0.2 0.011 15.2 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM90599.1 - 0.0085 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EIM90599.1 - 0.015 15.8 0.1 0.024 15.1 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EIM90599.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 EIM90599.1 - 0.039 13.3 0.1 7.2 5.9 0.1 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIM90599.1 - 0.19 10.9 0.1 0.36 9.9 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein zf-MYND PF01753.18 EIM90600.1 - 6.9e-10 38.9 12.2 1.2e-09 38.1 12.2 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM90600.1 - 0.11 12.8 8.3 0.19 12.1 8.3 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pho88 PF10032.9 EIM90602.1 - 1.4e-76 255.8 0.0 1.6e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2142 PF09913.9 EIM90602.1 - 0.093 11.6 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) PH PF00169.29 EIM90603.1 - 0.00068 20.1 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Ribosomal_60s PF00428.19 EIM90603.1 - 0.63 10.7 4.6 1.6 9.3 4.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Syntaxin_2 PF14523.6 EIM90603.1 - 0.64 10.4 5.2 4.1 7.8 0.2 2.5 1 1 1 2 2 2 0 Syntaxin-like protein UPF0086 PF01868.16 EIM90604.1 - 6.2e-31 106.2 0.0 9.6e-31 105.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Methyltransf_2 PF00891.18 EIM90605.1 - 3.9e-23 81.8 0.0 2.8e-22 79.0 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EIM90605.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM90605.1 - 0.00055 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM90605.1 - 0.0011 18.7 0.0 0.005 16.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM90605.1 - 0.0013 19.4 0.0 0.0038 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FAD_binding_3 PF01494.19 EIM90606.1 - 3.3e-60 204.2 0.0 2.2e-59 201.5 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.12 EIM90606.1 - 1.4e-26 93.5 0.0 2.3e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EIM90606.1 - 1.3e-05 24.5 2.0 2e-05 23.9 2.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM90606.1 - 1.3e-05 25.3 0.4 5.4e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIM90606.1 - 0.0001 21.2 0.7 0.00017 20.4 0.7 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM90606.1 - 0.00042 19.7 1.0 0.00062 19.1 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM90606.1 - 0.00049 19.4 0.1 0.0011 18.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM90606.1 - 0.00081 19.1 0.1 0.0024 17.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIM90606.1 - 0.0011 18.2 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EIM90606.1 - 0.0041 16.5 1.5 0.0059 16.0 1.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EIM90606.1 - 0.0056 15.8 0.9 0.0086 15.2 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EIM90606.1 - 0.012 14.6 1.5 0.022 13.8 1.5 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 EIM90606.1 - 0.013 15.1 0.5 0.05 13.2 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EIM90606.1 - 0.019 14.6 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EIM90606.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EIM90606.1 - 0.16 12.6 0.1 0.41 11.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.18 EIM90607.1 - 3.5e-26 91.8 0.0 5.3e-25 87.9 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EIM90607.1 - 0.00038 20.3 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM90607.1 - 0.0015 18.4 0.0 0.012 15.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM90607.1 - 0.0032 18.1 0.0 0.01 16.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM90607.1 - 0.01 16.5 0.0 0.058 14.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EIM90607.1 - 0.042 13.4 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EIM90607.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EIM90608.1 - 5.8e-23 81.3 0.0 1e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain Cpn10 PF00166.21 EIM90610.1 - 3.9e-28 97.3 0.0 4.5e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF373 PF04123.13 EIM90611.1 - 2.6 7.4 6.2 3.1 7.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Cation_efflux PF01545.21 EIM90612.1 - 1.4e-25 90.2 12.2 1.7e-25 89.9 12.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EIM90612.1 - 2.5e-05 24.3 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FAD_binding_3 PF01494.19 EIM90613.1 - 9e-17 61.3 0.0 5.2e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIM90613.1 - 0.0063 16.7 0.5 0.031 14.5 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM90613.1 - 0.015 14.9 1.5 0.044 13.4 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM90613.1 - 0.1 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM90613.1 - 0.17 10.7 0.9 0.27 10.0 0.9 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EIM90614.1 - 6.2e-16 58.6 0.0 1e-14 54.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM90614.1 - 6.1e-08 32.6 0.4 3.3e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM90614.1 - 9.1e-08 32.2 0.3 1.9e-07 31.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIM90614.1 - 1.2e-05 24.9 0.6 0.066 12.5 0.1 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EIM90614.1 - 1.5e-05 24.3 0.4 2.3e-05 23.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM90614.1 - 0.00071 18.9 0.0 0.0036 16.6 0.1 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM90614.1 - 0.00089 19.8 0.0 0.01 16.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM90614.1 - 0.0029 16.4 0.1 0.0086 14.8 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EIM90614.1 - 0.019 14.2 0.1 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM90614.1 - 0.028 14.4 0.2 0.11 12.5 0.2 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 EIM90614.1 - 0.037 13.3 0.3 0.071 12.3 0.3 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EIM90614.1 - 0.037 13.1 0.5 0.055 12.5 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EIM90614.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_transf_4 PF13439.6 EIM90614.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Methyltransf_2 PF00891.18 EIM90615.1 - 3.1e-18 65.8 0.0 3.7e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain GidB PF02527.15 EIM90615.1 - 0.054 12.8 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.14 EIM90615.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain UbiA PF01040.18 EIM90617.1 - 1.8e-32 112.6 17.1 2.4e-32 112.2 17.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_2 PF00891.18 EIM90618.1 - 5.1e-24 84.8 0.0 8.8e-23 80.7 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_2 PF00891.18 EIM90620.1 - 7e-28 97.4 0.0 3.7e-25 88.5 0.0 3.0 3 0 0 3 3 3 2 O-methyltransferase domain Methyltransf_25 PF13649.6 EIM90620.1 - 0.062 14.0 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EIM90620.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase HTH_25 PF13413.6 EIM90623.1 - 0.18 11.7 0.2 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_2 PF00891.18 EIM90624.1 - 7.4e-22 77.7 0.0 1.7e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain GidB PF02527.15 EIM90624.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 EIM90624.1 - 0.0098 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EIM90624.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 EIM90624.1 - 0.025 14.1 0.0 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 DUF608 PF04685.13 EIM90624.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Methyltransf_4 PF02390.17 EIM90624.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase SlyX PF04102.12 EIM90626.1 - 0.00023 21.7 0.5 0.00052 20.6 0.5 1.6 1 0 0 1 1 1 1 SlyX ZapB PF06005.12 EIM90626.1 - 0.032 14.7 0.1 0.066 13.7 0.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 EIM90626.1 - 0.16 12.6 0.1 0.34 11.6 0.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA ATG16 PF08614.11 EIM90626.1 - 1.5 9.0 8.1 0.13 12.5 0.4 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-MYND PF01753.18 EIM90627.1 - 2.3e-11 43.6 15.8 3.8e-11 42.9 15.8 1.4 1 0 0 1 1 1 1 MYND finger MIT PF04212.18 EIM90627.1 - 0.023 14.8 0.3 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Fer4_2 PF12797.7 EIM90627.1 - 0.54 10.5 5.3 16 5.8 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain SNARE_assoc PF09335.11 EIM90628.1 - 3.6e-18 66.2 8.9 3.6e-18 66.2 8.9 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein zf-MYND PF01753.18 EIM90630.1 - 3.3e-08 33.5 18.7 6.3e-08 32.6 18.7 1.5 1 0 0 1 1 1 1 MYND finger Pkinase_fungal PF17667.1 EIM90637.1 - 1e-27 97.0 0.0 3.5e-27 95.2 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EIM90637.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EIM90640.1 - 2.3e-60 204.2 0.0 3.5e-41 141.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90640.1 - 1.7e-26 93.0 0.3 2.5e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM90640.1 - 2.2e-05 23.6 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIM90640.1 - 0.00038 19.9 0.4 0.0009 18.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM90640.1 - 0.0089 16.0 0.1 0.061 13.2 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM90640.1 - 0.01 15.1 0.1 0.027 13.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EIM90640.1 - 0.039 12.7 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EIM90640.1 - 0.041 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 EIM90640.1 - 0.091 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EIM90641.1 - 3.3e-34 118.3 0.0 3.9e-31 108.2 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM90641.1 - 0.035 13.5 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Pkinase_fungal PF17667.1 EIM90642.1 - 2.1e-29 102.5 0.1 4.3e-29 101.5 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EIM90642.1 - 0.0008 18.9 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EIM90644.1 - 1.9e-27 96.1 0.0 3e-27 95.5 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 EIM90645.1 - 1.9e-52 178.5 0.0 8.1e-33 113.8 0.0 2.3 1 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM90645.1 - 0.0034 16.8 0.0 0.023 14.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90645.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 EIM90645.1 - 0.031 14.2 0.1 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.7 EIM90646.1 - 4.5e-07 29.7 1.3 8.3e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like DNA_pol_phi PF04931.13 EIM90646.1 - 0.0091 14.2 23.4 0.013 13.7 23.4 1.1 1 0 0 1 1 1 1 DNA polymerase phi Sigma70_ner PF04546.13 EIM90646.1 - 0.028 14.3 5.9 0.038 13.9 5.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 EIM90646.1 - 0.083 12.5 3.6 0.15 11.7 3.6 1.4 1 0 0 1 1 1 0 FAM176 family TFB6 PF17110.5 EIM90646.1 - 0.45 10.2 5.2 0.71 9.6 5.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 EIM90646.1 - 1.6 7.9 7.0 2.3 7.3 7.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 EIM90646.1 - 1.9 7.8 14.6 2.9 7.2 14.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 EIM90646.1 - 5.2 6.8 8.8 7.7 6.3 8.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GCIP PF13324.6 EIM90646.1 - 6.3 6.3 9.8 11 5.5 9.8 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 EIM90646.1 - 9.2 5.3 30.1 14 4.7 30.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-MYND PF01753.18 EIM90647.1 - 2.3e-07 30.8 13.6 4.4e-07 29.9 13.6 1.5 1 0 0 1 1 1 1 MYND finger SelP_N PF04592.14 EIM90647.1 - 6.3 6.1 6.7 15 4.9 6.7 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Beta-lactamase PF00144.24 EIM90648.1 - 2e-47 162.1 0.0 2.5e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Glutaminase PF04960.15 EIM90648.1 - 0.12 11.5 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 Glutaminase Beta-lactamase PF00144.24 EIM90649.1 - 1.3e-48 166.0 0.1 1.8e-48 165.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Glutaminase PF04960.15 EIM90649.1 - 0.0023 17.2 0.0 0.067 12.4 0.0 2.1 2 0 0 2 2 2 1 Glutaminase DUF4229 PF14012.6 EIM90649.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Beta-lactamase2 PF13354.6 EIM90649.1 - 0.15 11.7 0.0 0.83 9.2 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase enzyme family Methyltransf_2 PF00891.18 EIM90650.1 - 2.2e-26 92.4 0.0 9.9e-25 87.1 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 EIM90650.1 - 0.13 13.0 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Beta-lactamase PF00144.24 EIM90652.1 - 2e-49 168.7 0.0 2.9e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Glutaminase PF04960.15 EIM90652.1 - 0.24 10.5 0.0 1.6 7.9 0.0 1.9 2 0 0 2 2 2 0 Glutaminase Cir_N PF10197.9 EIM90653.1 - 0.00031 20.9 0.1 0.00031 20.9 0.1 3.2 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR CAP_N PF01213.19 EIM90653.1 - 8.7 5.7 11.5 3.8 6.9 4.8 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ADH_zinc_N PF00107.26 EIM90654.1 - 2.6e-27 95.3 0.1 3.7e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM90654.1 - 1.3e-15 58.6 0.0 2e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM90654.1 - 8e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EIM90654.1 - 0.077 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase F-box-like PF12937.7 EIM90655.1 - 5.2e-08 32.7 0.5 5.2e-08 32.7 0.5 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIM90655.1 - 0.00052 20.3 12.3 0.57 10.7 0.3 4.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) Methyltransf_2 PF00891.18 EIM90656.1 - 7.9e-17 61.3 0.0 3.7e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EIM90656.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 EIM90656.1 - 0.0025 17.8 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 EIM90656.1 - 0.039 14.7 0.0 0.082 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EIM90656.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain XFP PF03894.15 EIM90656.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase AhpC-TSA_2 PF13911.6 EIM90657.1 - 7.3e-05 22.9 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EIM90657.1 - 0.0002 21.3 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family COPIIcoated_ERV PF07970.12 EIM90658.1 - 2.2e-37 129.0 0.9 3.2e-37 128.5 0.9 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EIM90658.1 - 5.9e-22 77.8 0.0 1.2e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C3HC4_3 PF13920.6 EIM90662.1 - 1.9e-08 34.0 2.4 3.8e-08 33.0 2.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM90662.1 - 5.9e-08 32.5 2.4 8.9e-08 32.0 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM90662.1 - 5.2e-07 29.4 2.1 9.3e-07 28.6 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM90662.1 - 4.7e-06 26.8 2.9 7.4e-06 26.2 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EIM90662.1 - 2.2e-05 24.2 3.9 7.8e-05 22.5 4.0 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EIM90662.1 - 6.5e-05 22.9 2.5 6.5e-05 22.9 2.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM90662.1 - 0.0071 16.2 8.7 0.053 13.4 8.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIM90662.1 - 0.27 11.1 0.5 0.55 10.1 0.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EIM90662.1 - 4.2 7.6 7.5 20 5.4 7.9 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING GST_N PF02798.20 EIM90667.1 - 5.3e-20 71.5 0.0 8.2e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM90667.1 - 5.1e-19 68.5 0.0 7.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM90667.1 - 1.6e-13 50.7 0.0 2.3e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM90667.1 - 1.3e-10 41.4 0.0 2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM90667.1 - 1.6e-08 34.4 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM90667.1 - 5.7e-06 26.4 0.0 1.1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EIM90667.1 - 0.025 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.10 EIM90667.1 - 0.026 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) GST_N_4 PF17172.4 EIM90667.1 - 0.04 14.6 0.0 0.18 12.6 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 EIM90669.1 - 3.7e-18 65.6 0.0 7e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM90669.1 - 2.8e-16 59.5 0.1 4.8e-16 58.8 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIM90669.1 - 2.2e-15 56.8 0.0 4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM90669.1 - 4.4e-09 36.5 0.0 7.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIM90669.1 - 2.9e-08 33.8 0.1 5.3e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM90669.1 - 8.7e-07 28.9 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Transp_cyt_pur PF02133.15 EIM90670.1 - 2.1e-98 330.0 38.0 2.5e-98 329.7 38.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Hus1 PF04005.12 EIM90672.1 - 2.2e-73 246.9 0.2 2.4e-73 246.8 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Asp PF00026.23 EIM90673.1 - 1.5e-50 172.4 0.1 3.5e-50 171.2 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM90673.1 - 7.1e-08 32.9 0.8 3.5e-07 30.6 0.8 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EIM90673.1 - 0.1 13.2 0.3 9.1 6.9 0.1 3.4 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Abhydrolase_6 PF12697.7 EIM90674.1 - 1.8e-16 61.4 0.6 2.2e-16 61.1 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM90674.1 - 2.1e-09 37.0 0.0 2.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM90674.1 - 1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EIM90674.1 - 0.00092 19.0 0.0 0.053 13.3 0.0 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EIM90674.1 - 0.0087 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 EIM90674.1 - 0.069 12.9 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_28 PF02636.17 EIM90675.1 - 4.2e-63 213.4 0.0 5.5e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Copine PF07002.16 EIM90675.1 - 0.16 11.4 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Copine Epimerase PF01370.21 EIM90676.1 - 5.2e-17 62.1 0.0 7.7e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM90676.1 - 9.1e-11 41.7 0.0 2.5e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM90676.1 - 0.0013 18.7 0.0 0.01 15.7 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EIM90676.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 EIM90676.1 - 0.01 15.0 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 EIM90676.1 - 0.01 14.9 0.0 0.032 13.2 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro81C PF17652.1 EIM90678.1 - 1.3e-65 222.0 2.4 2.4e-65 221.1 2.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EIM90678.1 - 2.1e-23 83.0 0.1 5e-23 81.8 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 EIM90678.1 - 7.5e-11 42.2 0.0 0.03 14.5 0.0 5.6 4 2 2 6 6 6 3 Fascin domain FRG1 PF06229.12 EIM90678.1 - 0.00056 19.7 0.4 0.13 12.0 0.0 3.9 2 2 3 5 5 5 1 FRG1-like domain RicinB_lectin_2 PF14200.6 EIM90678.1 - 0.006 17.3 0.2 5.5 7.8 0.1 4.2 4 2 0 4 4 4 1 Ricin-type beta-trefoil lectin domain-like Abhydrolase_1 PF00561.20 EIM90679.1 - 6.5e-17 62.0 0.0 3.5e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EIM90679.1 - 2.2e-14 53.4 0.0 4.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF842 PF05811.13 EIM90679.1 - 0.12 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Abhydrolase_4 PF08386.10 EIM90680.1 - 6.6e-18 64.7 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EIM90680.1 - 4.1e-16 59.4 0.0 6.4e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold eIF-6 PF01912.18 EIM90682.1 - 1.4e-82 275.9 0.2 1.4e-82 275.9 0.2 1.5 2 0 0 2 2 2 1 eIF-6 family LRR_8 PF13855.6 EIM90683.1 - 5.1 6.9 8.1 35 4.3 0.0 3.9 3 1 0 3 3 3 0 Leucine rich repeat Isochorismatase PF00857.20 EIM90685.1 - 1.4e-10 41.6 0.0 3.7e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Isochorismatase family Aldo_ket_red PF00248.21 EIM90686.1 - 1.4e-48 165.6 0.0 2.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Egh16-like PF11327.8 EIM90688.1 - 5.3e-55 186.7 9.9 5.3e-55 186.7 9.9 2.2 2 0 0 2 2 2 1 Egh16-like virulence factor SOG2 PF10428.9 EIM90688.1 - 1.1 8.4 14.1 1.3 8.1 14.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 EIM90689.1 - 1.1e-22 80.4 58.3 1.6e-21 76.6 36.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EIM90689.1 - 8.9e-06 25.2 15.2 1.6e-05 24.4 15.2 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 EIM90689.1 - 0.00016 20.4 19.8 0.0044 15.6 19.8 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein CopD PF05425.13 EIM90689.1 - 0.035 14.5 2.3 0.046 14.1 0.0 2.3 2 1 1 3 3 3 0 Copper resistance protein D BRI3BP PF14965.6 EIM90689.1 - 0.23 10.9 7.0 0.67 9.4 1.0 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 KDZ PF18758.1 EIM90693.1 - 3.4e-54 183.8 0.0 5.4e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM90693.1 - 3.1e-34 117.3 0.3 1.6e-33 115.1 0.2 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM90693.1 - 2.1e-06 27.9 0.1 4.9e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 EIM90693.1 - 0.0061 16.7 5.4 0.018 15.2 5.4 1.8 1 0 0 1 1 1 1 B-box zinc finger CxC3 PF18804.1 EIM90693.1 - 0.0083 16.0 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CEBP_ZZ PF16366.5 EIM90693.1 - 0.033 14.4 4.0 0.082 13.2 4.0 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain AhpC-TSA_2 PF13911.6 EIM90694.1 - 3.4e-17 62.6 0.0 6.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 EIM90694.1 - 2.4e-06 27.3 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EIM90694.1 - 3.8e-05 23.6 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Aa_trans PF01490.18 EIM90696.1 - 8.1e-86 288.3 31.9 9.8e-86 288.0 31.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Epimerase PF01370.21 EIM90697.1 - 4.1e-16 59.2 0.0 6.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EIM90697.1 - 5.6e-11 42.1 0.1 3.5e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EIM90697.1 - 1.2e-09 37.6 0.0 2.1e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIM90697.1 - 9.4e-08 31.8 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EIM90697.1 - 3.9e-06 26.6 0.0 5.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EIM90697.1 - 6.9e-06 26.1 0.1 1.1e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EIM90697.1 - 0.18 11.7 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 KR domain APH PF01636.23 EIM90698.1 - 4.5e-14 53.0 0.0 8.4e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM90698.1 - 0.0026 17.1 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 EIM90698.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Mid2 PF04478.12 EIM90699.1 - 0.067 13.0 4.5 0.03 14.2 1.0 2.2 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF5305 PF17231.2 EIM90699.1 - 0.29 10.5 1.0 0.5 9.7 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 EIM90699.1 - 0.36 10.7 0.1 0.54 10.1 0.1 1.1 1 0 0 1 1 1 0 Rifin Viral_Beta_CD PF04530.12 EIM90699.1 - 0.96 9.8 3.5 1.2 9.5 2.0 1.9 1 1 0 1 1 1 0 Viral Beta C/D like family ECM11 PF15463.6 EIM90700.1 - 0.25 11.9 0.1 0.25 11.9 0.1 3.1 3 0 0 3 3 3 0 Extracellular mutant protein 11 Adeno_PV PF03910.13 EIM90700.1 - 0.74 8.5 5.3 1.3 7.6 5.3 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV Dynamin_N PF00350.23 EIM90701.1 - 8.8e-14 51.9 0.1 1.1e-12 48.3 0.0 2.8 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EIM90701.1 - 1.5e-06 28.2 0.0 4.2e-05 23.6 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM90701.1 - 3.6e-05 23.7 0.0 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EIM90701.1 - 0.00083 19.8 2.9 0.0075 16.7 0.0 3.6 2 1 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 EIM90701.1 - 0.0023 18.5 0.0 0.0072 16.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 EIM90701.1 - 0.0029 16.8 0.0 0.01 15.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain T2SSE PF00437.20 EIM90701.1 - 0.0049 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EIM90701.1 - 0.021 15.3 3.4 0.12 12.9 0.1 3.0 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EIM90701.1 - 0.027 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EIM90701.1 - 0.033 14.4 0.0 0.22 11.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 EIM90701.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FlxA PF14282.6 EIM90701.1 - 0.053 13.5 0.6 0.21 11.6 0.3 2.1 2 0 0 2 2 1 0 FlxA-like protein KAP_NTPase PF07693.14 EIM90701.1 - 0.056 12.7 0.0 0.19 10.9 0.0 1.8 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 EIM90701.1 - 0.095 12.4 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Swi5 PF07061.11 EIM90701.1 - 0.37 10.9 1.8 2.8 8.1 1.8 2.6 1 0 0 1 1 1 0 Swi5 RRF PF01765.19 EIM90701.1 - 2.2 8.2 13.8 3.8 7.4 0.1 3.1 3 0 0 3 3 3 0 Ribosome recycling factor GrpE PF01025.19 EIM90701.1 - 6.9 6.3 7.3 9.6 5.8 0.1 3.6 4 0 0 4 4 4 0 GrpE FMO-like PF00743.19 EIM90702.1 - 4.9e-12 45.1 0.6 2.5e-10 39.4 0.1 2.7 1 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EIM90702.1 - 8.9e-09 35.5 0.0 4.8e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM90702.1 - 0.0021 17.3 0.0 0.31 10.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM90702.1 - 0.0024 17.5 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM90702.1 - 0.0066 15.7 0.0 0.12 11.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM90702.1 - 0.0087 16.1 0.1 0.041 13.9 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EIM90702.1 - 0.013 14.7 0.1 2.2 7.4 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EIM90702.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 EIM90702.1 - 0.039 13.9 0.2 3.7 7.5 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PS_pyruv_trans PF04230.13 EIM90702.1 - 0.078 12.9 0.1 0.26 11.2 0.1 1.9 2 1 0 2 2 2 0 Polysaccharide pyruvyl transferase FAD_binding_2 PF00890.24 EIM90702.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EIM90702.1 - 0.27 10.5 0.2 0.99 8.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Fra10Ac1 PF09725.9 EIM90703.1 - 7.5e-47 158.5 0.0 1.1e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF2442 PF10387.9 EIM90704.1 - 0.19 12.0 0.3 12 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Abhydrolase_6 PF12697.7 EIM90705.1 - 8.7e-24 85.3 2.5 1.6e-23 84.5 2.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM90705.1 - 2.9e-06 26.7 0.0 4.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIM90705.1 - 1.2e-05 25.1 0.0 5.1e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EIM90705.1 - 0.0001 22.5 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain AAA PF00004.29 EIM90706.1 - 1.3e-91 303.9 0.0 4.8e-46 156.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM90706.1 - 5.2e-19 67.8 1.4 3.7e-08 33.0 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EIM90706.1 - 7.2e-15 55.1 0.0 1.5e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EIM90706.1 - 2.7e-11 44.1 1.7 0.003 18.0 0.2 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EIM90706.1 - 4.3e-11 43.2 0.0 0.00024 21.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EIM90706.1 - 2.5e-10 40.8 2.5 0.0078 16.5 0.1 5.2 3 2 1 4 4 3 2 AAA domain AAA_5 PF07728.14 EIM90706.1 - 3.2e-09 36.9 0.4 0.0036 17.3 0.2 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EIM90706.1 - 4.5e-09 36.0 0.0 0.00023 20.5 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 EIM90706.1 - 8.6e-09 35.7 0.0 0.0062 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EIM90706.1 - 1e-07 31.6 0.3 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EIM90706.1 - 9.6e-07 28.7 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EIM90706.1 - 9.9e-07 28.9 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EIM90706.1 - 2e-06 27.7 0.0 0.0048 16.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EIM90706.1 - 2.5e-06 27.5 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EIM90706.1 - 2.7e-06 27.7 0.0 0.046 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EIM90706.1 - 5e-06 26.5 2.0 0.04 13.8 0.1 3.7 4 0 0 4 4 3 2 NACHT domain RNA_helicase PF00910.22 EIM90706.1 - 5.1e-06 26.8 0.0 0.16 12.4 0.0 2.7 2 1 0 2 2 2 2 RNA helicase Cytidylate_kin2 PF13189.6 EIM90706.1 - 8.2e-06 26.1 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 2 Cytidylate kinase-like family Zeta_toxin PF06414.12 EIM90706.1 - 1.6e-05 24.3 0.1 0.055 12.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 EIM90706.1 - 1.8e-05 24.7 0.0 0.078 12.9 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 EIM90706.1 - 2.2e-05 25.0 0.0 0.18 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EIM90706.1 - 0.00017 22.2 0.0 0.62 10.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter Sigma54_activat PF00158.26 EIM90706.1 - 0.0002 21.1 0.0 0.99 9.1 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 EIM90706.1 - 0.00045 19.8 3.1 1.3 8.6 0.1 4.1 2 2 0 4 4 4 1 AAA domain AAA_17 PF13207.6 EIM90706.1 - 0.0007 20.0 0.4 1.9 8.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 EIM90706.1 - 0.0008 18.8 0.0 6.5 6.0 0.0 3.2 3 0 0 3 3 3 0 KaiC Viral_helicase1 PF01443.18 EIM90706.1 - 0.0011 18.8 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.16 EIM90706.1 - 0.0014 17.6 0.0 0.59 9.0 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase AAA_11 PF13086.6 EIM90706.1 - 0.0017 18.2 0.2 2.8 7.7 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EIM90706.1 - 0.002 17.7 0.0 2.7 7.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 EIM90706.1 - 0.002 18.2 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EIM90706.1 - 0.0027 16.9 0.1 1.5 8.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EIM90706.1 - 0.006 16.3 0.1 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EIM90706.1 - 0.0068 15.6 0.0 0.38 9.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SKI PF01202.22 EIM90706.1 - 0.0069 16.5 0.0 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 EIM90706.1 - 0.0074 15.8 0.2 1.8 7.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 EIM90706.1 - 0.0089 16.0 0.0 7.3 6.4 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 EIM90706.1 - 0.01 15.3 0.0 16 4.8 0.0 3.7 3 1 0 3 3 3 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EIM90706.1 - 0.014 14.5 0.1 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 EIM90706.1 - 0.045 13.7 0.2 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Cytidylate_kin PF02224.18 EIM90706.1 - 0.064 13.0 0.2 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Bac_DnaA PF00308.18 EIM90706.1 - 0.092 12.6 0.0 11 5.8 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 EIM90706.1 - 0.1 12.9 1.5 7.4 6.9 0.2 2.9 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EIM90706.1 - 0.12 12.1 0.1 16 5.2 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.16 EIM90706.1 - 0.21 11.0 0.1 7.5 5.9 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase PRCC PF10253.9 EIM90706.1 - 0.3 11.9 6.2 0.056 14.2 2.3 1.7 2 0 0 2 2 1 0 Mitotic checkpoint regulator, MAD2B-interacting Serglycin PF04360.12 EIM90708.1 - 0.024 14.6 6.9 1.1 9.2 4.6 2.3 2 0 0 2 2 2 0 Serglycin CYYR1 PF10873.8 EIM90710.1 - 1.2 9.6 14.7 1.3 9.5 13.1 1.9 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 F-box-like PF12937.7 EIM90711.1 - 0.025 14.4 1.4 0.043 13.7 0.4 2.0 2 0 0 2 2 2 0 F-box-like Ribosomal_L30 PF00327.20 EIM90713.1 - 1.3e-08 34.6 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PTCB-BRCT PF12738.7 EIM90714.1 - 1.3e-30 105.2 0.7 1.6e-12 47.2 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EIM90714.1 - 1.4e-19 70.3 0.3 7.8e-07 29.4 0.0 4.4 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EIM90714.1 - 7.2e-06 26.3 0.0 2.7 8.5 0.0 5.3 4 1 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EIM90714.1 - 0.01 15.7 0.0 3.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain F-box-like PF12937.7 EIM90715.1 - 7.7e-08 32.1 0.2 2.4e-07 30.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM90715.1 - 0.094 12.6 0.2 0.35 10.8 0.2 2.0 1 0 0 1 1 1 0 F-box domain Glyco_hydro_3_C PF01915.22 EIM90718.1 - 1.8e-51 175.0 0.0 2.7e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIM90718.1 - 3.6e-43 148.2 0.1 6.3e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIM90718.1 - 1.6e-22 79.3 0.7 3.3e-22 78.4 0.7 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FmdA_AmdA PF03069.15 EIM90719.1 - 4.8e-153 509.4 0.0 6.7e-153 509.0 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family Arrestin_N PF00339.29 EIM90720.1 - 1.1e-05 25.5 2.0 3.7e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EIM90720.1 - 0.023 15.1 0.0 0.53 10.7 0.0 2.8 2 2 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain FAD_binding_3 PF01494.19 EIM90721.1 - 1.3e-21 77.3 0.0 2.5e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM90721.1 - 5.7e-09 36.0 0.2 4.7e-05 23.1 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EIM90721.1 - 8.9e-09 34.5 0.2 6.1e-08 31.8 0.2 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EIM90721.1 - 4.1e-08 32.8 0.0 6.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM90721.1 - 1.2e-06 28.7 0.7 1.1e-05 25.5 0.5 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIM90721.1 - 7.1e-06 25.4 0.8 2.1e-05 23.8 0.1 1.9 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EIM90721.1 - 1.7e-05 25.3 0.7 0.0078 16.7 0.1 3.1 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM90721.1 - 2e-05 24.1 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM90721.1 - 2.3e-05 23.8 0.1 0.00082 18.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EIM90721.1 - 0.0009 18.6 0.1 0.088 12.1 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 EIM90721.1 - 0.0077 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EIM90721.1 - 0.017 14.0 0.4 0.085 11.7 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EIM90721.1 - 0.023 13.7 0.0 0.67 8.9 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EIM90721.1 - 0.037 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EIM90722.1 - 1.6e-18 67.1 0.0 4.5e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM90722.1 - 1.4e-07 31.7 0.6 1.5e-06 28.3 0.8 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM90722.1 - 2e-07 30.9 7.9 3e-06 27.1 1.3 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM90722.1 - 3.1e-07 29.8 0.1 6.1e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM90722.1 - 1.9e-06 27.3 0.0 5.9e-06 25.7 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM90722.1 - 1e-05 24.4 0.1 4.5e-05 22.3 0.2 2.0 2 1 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EIM90722.1 - 2.9e-05 24.5 0.1 0.0058 17.2 0.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM90722.1 - 0.0002 20.8 0.1 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EIM90722.1 - 0.0017 17.7 0.1 0.26 10.5 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EIM90722.1 - 0.0067 15.8 1.0 0.01 15.2 1.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIM90722.1 - 0.024 13.5 0.9 0.11 11.3 0.2 2.2 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 EIM90722.1 - 0.048 12.7 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 EIM90722.1 - 0.05 12.8 0.2 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 EIM90722.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 EIM90723.1 - 5.9e-69 233.0 0.0 7e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT PF03062.19 EIM90724.1 - 4.9e-46 157.7 13.1 4.9e-46 157.7 13.1 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family F-box-like PF12937.7 EIM90728.1 - 2.2e-10 40.3 0.5 6.9e-10 38.7 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM90728.1 - 0.0006 19.6 1.5 0.02 14.8 0.5 2.8 2 0 0 2 2 2 1 F-box domain ICMT PF04140.14 EIM90731.1 - 5.4e-15 55.6 0.3 2.7e-14 53.4 0.2 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM90731.1 - 5.5e-12 46.0 0.7 3e-11 43.7 0.7 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EIM90731.1 - 6.2e-08 31.8 0.7 7.4e-08 31.6 0.7 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIM90731.1 - 5.3e-05 22.8 0.4 0.00012 21.7 0.2 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) MFS_1 PF07690.16 EIM90732.1 - 2.6e-23 82.5 74.8 9e-17 61.0 41.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UbiA PF01040.18 EIM90733.1 - 3.5e-48 164.1 19.0 4.5e-48 163.7 19.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GMC_oxred_N PF00732.19 EIM90734.1 - 8.5e-57 192.8 0.0 1.2e-56 192.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM90734.1 - 9.4e-34 117.0 0.0 1.8e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIM90734.1 - 0.00016 21.9 0.5 0.0012 19.1 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM90734.1 - 0.0035 16.4 0.2 0.0055 15.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM90734.1 - 0.0041 16.3 0.7 0.086 11.9 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EIM90734.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 EIM90734.1 - 0.015 14.9 0.2 0.18 11.3 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase CK_II_beta PF01214.18 EIM90735.1 - 5.3e-77 257.7 0.0 6.5e-77 257.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Glutaredoxin PF00462.24 EIM90737.1 - 7.2e-19 67.8 0.0 5e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EIM90737.1 - 2.1e-13 50.2 0.0 3.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 EIM90737.1 - 8.9e-07 28.8 0.0 8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EIM90737.1 - 8.8e-05 22.8 0.0 0.017 15.5 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Phosducin PF02114.16 EIM90737.1 - 0.0041 16.1 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin SH3BGR PF04908.15 EIM90737.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.7 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Thioredoxin_2 PF13098.6 EIM90737.1 - 0.03 14.8 0.0 0.78 10.2 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin-like domain HicA_toxin PF07927.12 EIM90738.1 - 6.4e-05 22.9 0.0 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, Bac_small_YrzI PF09501.10 EIM90738.1 - 1.9 8.7 4.1 6.3 7.0 4.1 2.0 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) HicA_toxin PF07927.12 EIM90739.1 - 0.0042 17.1 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Ku PF02735.16 EIM90740.1 - 2.8e-33 115.3 0.0 5.2e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EIM90740.1 - 8.2e-22 78.0 0.0 1.6e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EIM90740.1 - 1.8e-16 60.6 0.3 1.8e-16 60.6 0.3 1.9 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EIM90740.1 - 1.5e-10 40.6 0.1 2.9e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 EIM90740.1 - 0.0028 18.3 0.0 0.045 14.4 0.0 2.8 2 1 0 2 2 2 1 von Willebrand factor type A domain SPC12 PF06645.13 EIM90741.1 - 0.43 10.7 2.2 0.4 10.8 0.2 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2207 PF09972.9 EIM90741.1 - 1.6 7.4 3.4 1.3 7.7 0.2 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) NAD_binding_4 PF07993.12 EIM90742.1 - 7e-33 113.9 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM90742.1 - 1.3e-24 86.6 0.0 2.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EIM90742.1 - 4.6e-09 36.1 0.0 7.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM90742.1 - 7.4e-06 25.2 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EIM90742.1 - 0.00042 20.3 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 EIM90742.1 - 0.0026 18.1 0.0 0.0072 16.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Orn_Arg_deC_N PF02784.16 EIM90744.1 - 1.2e-78 263.9 0.0 1.5e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EIM90744.1 - 1e-16 60.9 0.0 1.2e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EIM90744.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel KilA-N PF04383.13 EIM90745.1 - 0.0017 18.2 0.1 0.016 15.1 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain SPX PF03105.19 EIM90746.1 - 5.6e-33 115.4 16.4 2.1e-21 77.3 8.4 2.9 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EIM90746.1 - 2.2e-26 93.0 24.5 3.6e-26 92.2 24.5 1.3 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EIM90746.1 - 9.9e-23 80.8 33.7 1.9e-16 60.2 14.2 2.2 1 1 0 2 2 2 2 Citrate transporter TFIIF_alpha PF05793.12 EIM90746.1 - 0.21 10.2 5.4 0.31 9.6 5.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 EIM90746.1 - 1.9 8.2 8.3 3.2 7.4 8.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EIM90746.1 - 2.1 8.8 11.4 5.1 7.5 11.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mis14 PF08641.12 EIM90746.1 - 4.7 7.5 5.8 0.64 10.3 0.8 2.1 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Sdh_cyt PF01127.22 EIM90747.1 - 2.3e-25 89.0 0.2 2.8e-25 88.7 0.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pyr_redox_2 PF07992.14 EIM90748.1 - 3.6e-30 105.2 0.0 5.2e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM90748.1 - 2.1e-13 50.6 0.1 3e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM90748.1 - 0.0041 16.8 1.2 1.4 8.4 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM90748.1 - 0.0067 15.7 0.1 0.18 11.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PCP_red PF08369.10 EIM90748.1 - 0.19 12.0 0.4 0.5 10.6 0.4 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Thi4 PF01946.17 EIM90748.1 - 0.21 10.8 2.1 35 3.5 0.0 3.1 3 0 0 3 3 3 0 Thi4 family Pyr_redox_2 PF07992.14 EIM90749.1 - 1e-31 110.3 0.0 1.8e-31 109.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM90749.1 - 1.3e-15 57.7 0.1 5.9e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM90749.1 - 0.00035 20.6 0.0 2 8.4 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EIM90749.1 - 0.00052 19.4 0.0 0.0089 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EIM90749.1 - 0.00067 20.1 0.2 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 EIM90749.1 - 0.002 17.4 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EIM90749.1 - 0.0037 16.9 0.2 1.3 8.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM90749.1 - 0.0089 15.1 0.6 1.7 7.6 0.1 2.4 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM90749.1 - 0.066 12.3 0.3 2.6 7.0 0.0 2.3 2 1 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 EIM90749.1 - 0.067 13.5 0.1 5.6 7.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 EIM90749.1 - 0.15 10.7 0.0 8.4 5.0 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein Hva1_TUDOR PF11160.8 EIM90750.1 - 7.7e-12 45.2 3.2 1.5e-11 44.3 3.2 1.5 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain F-box-like PF12937.7 EIM90751.1 - 0.00032 20.5 0.5 0.0015 18.4 0.5 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM90751.1 - 0.0004 20.2 0.7 0.0004 20.2 0.7 2.7 3 0 0 3 3 3 1 F-box domain PTPA PF03095.15 EIM90753.1 - 2.9e-101 338.9 0.0 3.4e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein ERAP1_C PF11838.8 EIM90754.1 - 7.8e-71 239.2 2.1 1.2e-70 238.5 2.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EIM90754.1 - 1.3e-70 237.4 0.2 2.1e-70 236.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EIM90754.1 - 1.2e-38 133.1 0.0 4.9e-38 131.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Glyco_hydro_18 PF00704.28 EIM90755.1 - 5.4e-13 49.4 0.3 6.6e-13 49.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 EIM90755.1 - 0.0017 18.8 0.6 0.0017 18.8 0.6 3.7 3 0 0 3 3 3 1 Carbohydrate binding domain zf-MYND PF01753.18 EIM90756.1 - 1e-07 31.9 15.0 2.3e-07 30.8 15.0 1.7 1 0 0 1 1 1 1 MYND finger Phage_terminase PF10668.9 EIM90756.1 - 0.031 14.3 0.3 13 5.9 0.1 2.7 1 1 0 2 2 2 0 Phage terminase small subunit zf-Mss51 PF13824.6 EIM90756.1 - 0.76 9.9 5.5 7.6 6.7 5.9 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_M1 PF01433.20 EIM90757.1 - 1.8e-71 240.2 0.2 4.6e-71 238.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 EIM90757.1 - 1.3e-70 238.4 3.8 2e-70 237.9 3.8 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EIM90757.1 - 9e-37 127.1 0.4 1.7e-35 122.9 0.4 2.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 EIM90757.1 - 0.024 15.0 0.9 1.3 9.5 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats Acyltransferase PF01553.21 EIM90759.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase DUF2573 PF10835.8 EIM90760.1 - 0.052 13.9 0.6 11 6.4 0.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2573) Maf PF02545.14 EIM90763.1 - 3.4e-42 144.1 0.0 4.3e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein DSBA PF01323.20 EIM90765.1 - 8.9e-21 74.5 0.0 1.1e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.25 EIM90766.1 - 1e-27 96.9 1.6 4.3e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM90766.1 - 7.7e-24 84.5 1.3 6.2e-21 75.0 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM90766.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain AceK PF06315.11 EIM90766.1 - 0.18 10.3 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DUF1776 PF08643.10 EIM90766.1 - 0.19 11.1 0.0 0.86 8.9 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) FHA PF00498.26 EIM90767.1 - 8.1e-09 35.7 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EIM90767.1 - 0.026 14.8 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain XLF PF09302.11 EIM90768.1 - 1.8e-08 34.8 0.1 2.8e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DTHCT PF08070.11 EIM90768.1 - 0.0013 19.4 15.2 0.0013 19.4 15.2 2.1 2 0 0 2 2 2 1 DTHCT (NUC029) region Antimicrobial14 PF08109.11 EIM90770.1 - 0.045 13.8 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Lactocin 705 family Cyclin_N PF00134.23 EIM90772.1 - 8.3e-44 148.4 0.0 3e-43 146.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIM90772.1 - 1.9e-24 86.0 0.0 4.7e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Tup_N PF08581.10 EIM90772.1 - 1 9.7 4.9 0.67 10.3 1.6 2.2 2 0 0 2 2 2 0 Tup N-terminal ADH_N_2 PF16884.5 EIM90773.1 - 1.6e-26 92.3 0.0 3e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EIM90773.1 - 1.6e-18 66.9 0.0 2.8e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM90773.1 - 1.8e-10 42.0 0.0 3.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyoxal_oxid_N PF07250.11 EIM90773.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus adh_short PF00106.25 EIM90773.1 - 0.06 12.8 0.2 0.15 11.5 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.26 EIM90774.1 - 1.6e-18 66.9 0.1 4.6e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM90774.1 - 4.2e-09 36.2 0.0 1e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM90774.1 - 9.2e-05 23.5 0.0 0.00015 22.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RhoGEF PF00621.20 EIM90775.1 - 1.2e-31 110.4 0.0 1.7e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 EIM90775.1 - 2.6e-29 102.7 0.0 3.9e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EIM90775.1 - 1.7e-07 31.4 0.0 6.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EIM90775.1 - 0.025 15.1 0.0 0.085 13.4 0.0 2.0 2 0 0 2 2 2 0 PH domain PUA_3 PF17785.1 EIM90775.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 PUA-like domain Peptidase_C14 PF00656.22 EIM90777.1 - 5.2e-23 82.3 0.0 8.8e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 EIM90778.1 - 2.5e-18 66.9 0.0 5.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM90779.1 - 1.2e-34 120.1 0.0 1.9e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM90779.1 - 2.8e-21 74.7 27.6 0.012 15.5 0.0 15.1 16 0 0 16 16 16 6 Tetratricopeptide repeat TPR_8 PF13181.6 EIM90779.1 - 2e-13 49.4 0.0 0.16 12.2 0.0 11.0 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM90779.1 - 3.6e-12 45.4 7.3 0.18 12.0 0.0 11.0 12 1 1 13 13 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM90779.1 - 5.7e-12 45.8 21.0 3.1 8.2 1.6 12.1 7 4 5 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIM90779.1 - 2.1e-09 36.8 4.4 0.17 11.8 0.0 9.8 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM90779.1 - 6.7e-09 35.3 6.9 0.014 15.1 0.0 8.5 11 0 0 11 11 11 2 TPR repeat TPR_7 PF13176.6 EIM90779.1 - 5.1e-08 32.4 5.7 2.8 8.2 0.1 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM90779.1 - 0.00018 22.0 9.3 2.6 8.8 0.0 6.9 5 1 3 8 8 8 3 Tetratricopeptide repeat CRISPR_Cse2 PF09485.10 EIM90779.1 - 0.0056 17.2 11.3 4.2 7.9 0.1 7.6 4 3 3 7 7 7 1 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_15 PF13429.6 EIM90779.1 - 0.0058 15.9 1.8 4.1 6.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EIM90779.1 - 0.019 15.0 0.0 67 3.7 0.0 5.5 6 0 0 6 6 6 0 Exonuclease VII small subunit Surfac_D-trimer PF09006.11 EIM90779.1 - 0.042 13.7 0.0 13 5.7 0.0 4.1 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation TPR_14 PF13428.6 EIM90779.1 - 0.07 14.0 19.4 0.92 10.5 0.1 8.5 12 0 0 12 12 7 0 Tetratricopeptide repeat MIT PF04212.18 EIM90779.1 - 0.1 12.7 0.1 41 4.3 0.0 4.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 EIM90779.1 - 0.22 11.8 0.8 1.6e+02 2.6 0.0 5.4 6 1 1 7 7 7 0 MIT domain of nuclear receptor-binding factor 2 Mannitol_dh_C PF08125.13 EIM90780.1 - 8.3e-07 28.7 0.0 1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Peptidase_C14 PF00656.22 EIM90781.1 - 9.7e-15 55.2 0.0 1.6e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DIM1 PF02966.16 EIM90781.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 Peroxin-3 PF04882.12 EIM90782.1 - 0.96 8.4 10.4 0.5 9.3 0.5 2.1 2 0 0 2 2 2 0 Peroxin-3 Dicty_REP PF05086.12 EIM90782.1 - 2.1 6.2 3.2 3.2 5.6 3.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acetyltransf_3 PF13302.7 EIM90783.1 - 2.3e-15 57.5 0.0 3.4e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM90783.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Asp PF00026.23 EIM90784.1 - 1.2e-41 143.1 0.2 2.2e-41 142.3 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM90784.1 - 2.4e-06 27.9 6.3 3e-06 27.6 1.2 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Cullin PF00888.22 EIM90785.1 - 7.5e-190 632.6 0.0 9.1e-190 632.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EIM90785.1 - 1.7e-27 95.2 1.6 3.8e-27 94.1 1.6 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Xpo1 PF08389.12 EIM90786.1 - 1.8e-20 73.5 0.4 6.3e-19 68.5 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 EIM90786.1 - 0.0095 16.3 0.1 0.9 10.0 0.1 3.7 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 EIM90786.1 - 0.054 13.8 0.2 0.76 10.2 0.1 3.2 2 0 0 2 2 2 0 HEAT repeat DnaJ_C PF01556.18 EIM90788.1 - 4.2e-30 104.8 0.0 6.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIM90788.1 - 4.1e-23 81.3 3.4 6.4e-23 80.7 3.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIM90788.1 - 2e-14 53.7 14.7 3.6e-14 52.9 14.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EIM90788.1 - 2.1e-05 24.5 3.6 0.1 12.6 0.8 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EIM90788.1 - 0.00033 20.5 11.9 0.077 13.0 3.7 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EIM90788.1 - 0.022 14.5 3.5 0.031 13.9 0.1 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EIM90788.1 - 0.071 13.5 0.7 0.071 13.5 0.7 3.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-IS66 PF13005.7 EIM90788.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.5 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 DZR PF12773.7 EIM90788.1 - 0.3 11.1 8.6 0.78 9.8 8.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon YL1_C PF08265.11 EIM90789.1 - 1.1e-14 53.9 0.6 1.5e-14 53.5 0.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain 7TM_GPCR_Sru PF10322.9 EIM90791.1 - 0.38 10.0 5.5 1.1 8.5 0.5 2.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru Acetyltransf_2 PF00797.17 EIM90792.1 - 1e-20 74.6 0.1 1e-17 64.7 0.1 3.1 2 1 0 2 2 2 1 N-acetyltransferase Ribosomal_L10 PF00466.20 EIM90793.1 - 2.7e-23 82.0 0.3 6.5e-23 80.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EIM90793.1 - 3.9e-22 78.0 0.0 7.1e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EIM90793.1 - 4.6e-19 68.8 8.6 4.6e-19 68.8 8.6 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein PPR_2 PF13041.6 EIM90794.1 - 0.0059 16.8 0.1 1.9 8.8 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family Glyco_hydro_3 PF00933.21 EIM90800.1 - 1.9e-06 27.5 0.1 0.0039 16.6 0.0 3.0 2 1 1 3 3 3 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EIM90800.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain STE3 PF02076.15 EIM90801.1 - 0.00062 19.1 0.2 0.00079 18.7 0.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor HLH PF00010.26 EIM90802.1 - 2e-06 27.6 0.0 1.2e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 EIM90804.1 - 6.3e-33 114.1 31.4 6.3e-33 114.1 31.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM90804.1 - 1.8e-09 37.0 9.3 1.8e-09 37.0 9.3 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter ABC_tran PF00005.27 EIM90805.1 - 7.9e-51 172.2 0.1 2.8e-27 95.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIM90805.1 - 5.4e-49 167.3 29.9 2.4e-27 96.3 15.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EIM90805.1 - 1.6e-07 31.0 3.2 0.00057 19.4 1.1 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EIM90805.1 - 2e-05 24.6 2.2 0.054 13.6 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EIM90805.1 - 3.1e-05 24.4 1.8 0.028 14.8 0.0 3.1 2 2 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIM90805.1 - 5.4e-05 23.1 0.7 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EIM90805.1 - 0.00065 19.4 0.8 1.8 8.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EIM90805.1 - 0.005 16.7 2.0 2.5 7.8 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EIM90805.1 - 0.0059 16.1 0.6 0.61 9.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 EIM90805.1 - 0.02 15.4 0.0 8.9 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EIM90805.1 - 0.02 14.5 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EIM90805.1 - 0.021 14.5 0.2 7.6 6.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EIM90805.1 - 0.023 14.6 0.2 0.58 10.0 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EIM90805.1 - 0.029 14.7 3.4 2.5 8.3 0.3 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EIM90805.1 - 0.035 14.0 1.5 1.7 8.5 0.1 3.3 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 EIM90805.1 - 0.04 13.2 0.4 2.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EIM90805.1 - 0.1 12.3 0.4 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIM90805.1 - 0.13 12.7 0.4 11 6.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Roc PF08477.13 EIM90805.1 - 0.24 11.6 1.1 9.4 6.5 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EIM90805.1 - 0.28 11.6 1.3 12 6.4 0.1 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EIM90805.1 - 0.32 11.0 0.8 5.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 EIM90805.1 - 1.6 8.8 4.8 0.49 10.5 0.5 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_11 PF13086.6 EIM90805.1 - 2.3 7.9 5.3 7 6.3 0.0 3.1 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 EIM90805.1 - 7.9 6.5 12.3 1.2 9.2 0.7 2.7 3 0 0 3 3 2 0 Dynamin family SH3_9 PF14604.6 EIM90807.1 - 1.1e-12 47.6 0.1 1.6e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIM90807.1 - 2.3e-12 46.3 0.2 3.3e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EIM90807.1 - 2.8e-12 46.1 0.0 4.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DSBA PF01323.20 EIM90808.1 - 1.9e-29 102.8 0.0 2.2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EIM90808.1 - 5e-05 23.5 0.4 0.00021 21.5 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_5 PF13743.6 EIM90808.1 - 0.0083 15.8 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Amidohydro_3 PF07969.11 EIM90808.1 - 0.035 13.6 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family Thioredoxin_3 PF13192.6 EIM90808.1 - 0.075 13.1 0.1 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain YdjC PF04794.12 EIM90808.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 YdjC-like protein WD40 PF00400.32 EIM90809.1 - 1.8e-14 53.8 7.9 4.4e-08 33.7 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90809.1 - 9.5e-08 32.2 0.0 7.1e-05 23.0 0.0 2.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM90809.1 - 2.9e-06 27.3 0.4 4.5e-06 26.7 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EIM90809.1 - 0.00043 20.1 2.8 0.047 13.6 0.0 3.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EIM90809.1 - 0.0029 17.2 1.8 0.46 10.2 0.1 3.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 EIM90809.1 - 0.01 14.4 0.0 0.024 13.2 0.0 1.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EIM90809.1 - 0.013 14.6 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Lactonase PF10282.9 EIM90809.1 - 0.015 14.5 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PAP2_C PF14360.6 EIM90809.1 - 0.032 14.8 0.2 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal WD40_like PF17005.5 EIM90809.1 - 0.037 13.4 0.0 0.058 12.7 0.0 1.3 1 1 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 EIM90809.1 - 0.059 12.3 0.1 0.19 10.6 0.0 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 EIM90809.1 - 0.2 10.9 0.0 2.2 7.5 0.0 2.0 1 1 0 1 1 1 0 CPSF A subunit region FDX-ACB PF03147.14 EIM90810.1 - 0.052 14.0 0.3 9.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain MAT1 PF06391.13 EIM90810.1 - 0.071 12.9 8.0 0.1 12.4 8.0 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Pkinase PF00069.25 EIM90811.1 - 6.3e-24 84.8 0.0 7.8e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90811.1 - 6.7e-10 38.7 0.0 9.5e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM90811.1 - 2.8e-08 33.0 0.0 4.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM90811.1 - 0.0007 19.6 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family SET PF00856.28 EIM90812.1 - 1.2e-11 45.3 0.0 4.1e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 SET domain F-box-like PF12937.7 EIM90813.1 - 0.037 13.9 1.5 0.1 12.5 0.9 2.2 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 EIM90814.1 - 1.8e-08 34.2 0.1 6.8e-08 32.3 0.1 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM90814.1 - 0.17 12.3 6.5 20 5.7 0.1 5.3 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) Ribosomal_S10 PF00338.22 EIM90815.1 - 2.2e-28 98.3 0.4 2.6e-28 98.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF572 PF04502.13 EIM90816.1 - 1.9e-68 231.5 0.1 2.3e-68 231.3 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) SUV3_C PF12513.8 EIM90816.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Med15_fungi PF05397.12 EIM90817.1 - 7.2e-05 23.0 2.5 0.00017 21.8 2.5 1.6 1 0 0 1 1 1 1 Mediator complex subunit 15 CDC27 PF09507.10 EIM90817.1 - 0.038 13.4 10.6 0.071 12.5 10.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 EIM90817.1 - 0.89 8.3 7.5 1.6 7.5 7.5 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF572 PF04502.13 EIM90819.1 - 3.5e-65 220.8 0.7 3.8e-65 220.7 0.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) ARID PF01388.21 EIM90820.1 - 2.9e-12 47.1 1.3 1.2e-11 45.1 0.0 2.8 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain 5_3_exonuc PF01367.20 EIM90820.1 - 0.00031 21.3 0.1 0.00078 20.0 0.1 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Med15_fungi PF05397.12 EIM90820.1 - 0.0005 20.3 2.4 0.0005 20.3 2.4 3.9 4 0 0 4 4 4 1 Mediator complex subunit 15 Phasin_2 PF09361.10 EIM90822.1 - 0.056 13.7 0.1 0.086 13.1 0.1 1.3 1 0 0 1 1 1 0 Phasin protein Fungal_trans PF04082.18 EIM90825.1 - 6.5e-13 48.3 0.0 9.9e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM90825.1 - 2.8e-07 30.6 14.0 5.1e-07 29.7 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.18 EIM90826.1 - 1e-22 80.7 0.1 1.2e-22 80.6 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_M20 PF01546.28 EIM90827.1 - 1.8e-20 73.5 0.0 2.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2207 PF09972.9 EIM90827.1 - 0.03 13.1 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_hydroxylase PF04116.13 EIM90827.1 - 0.048 14.0 0.7 0.048 14.0 0.7 1.6 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily 2TM PF13239.6 EIM90827.1 - 0.073 13.4 2.7 0.16 12.3 2.7 1.5 1 0 0 1 1 1 0 2TM domain DnaJ PF00226.31 EIM90828.1 - 1e-16 60.8 0.1 1.8e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Nucleo_P87 PF07267.11 EIM90828.1 - 0.017 14.0 0.8 0.024 13.5 0.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 cobW PF02492.19 EIM90829.1 - 1.2e-40 139.0 0.1 1.5e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EIM90829.1 - 0.00039 20.3 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EIM90829.1 - 0.0088 15.9 0.0 0.022 14.7 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EIM90829.1 - 0.044 14.1 0.3 0.86 9.9 0.3 2.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EIM90829.1 - 0.056 13.3 0.4 3.5 7.5 0.0 2.6 1 1 1 3 3 3 0 RsgA GTPase Frag1 PF10277.9 EIM90830.1 - 1.7e-33 116.0 7.9 5e-33 114.5 7.9 1.9 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EIM90830.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Adaptin_N PF01602.20 EIM90831.1 - 5.7e-117 391.4 0.4 8.1e-117 390.9 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EIM90831.1 - 5.3e-15 55.8 0.7 1.6e-12 47.8 0.0 3.9 2 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIM90831.1 - 8e-07 29.4 4.6 0.0093 16.3 0.1 4.9 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 EIM90831.1 - 0.017 15.4 8.5 8.2 7.0 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat Cohesin_HEAT PF12765.7 EIM90831.1 - 0.023 15.0 3.9 1.9 8.9 0.1 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion SAPS PF04499.15 EIM90831.1 - 0.17 10.7 2.2 0.24 10.2 2.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.13 EIM90831.1 - 0.19 11.7 13.2 0.31 11.0 13.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 EIM90832.1 - 9.2e-30 104.1 2.9 1.5e-25 90.3 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family ESCRT-II PF05871.12 EIM90833.1 - 1.4e-31 109.6 0.1 2e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sugar_tr PF00083.24 EIM90835.1 - 2.5e-97 326.6 17.5 3.4e-97 326.2 17.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM90835.1 - 1.6e-20 73.4 32.9 1.6e-20 73.4 32.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM90835.1 - 6.8e-05 21.5 1.2 0.00011 20.8 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEMspv1-c74-12 PF11044.8 EIM90836.1 - 0.0047 16.9 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein SH3_9 PF14604.6 EIM90836.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 EIM90836.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 SH3 domain WD40 PF00400.32 EIM90838.1 - 6.3e-10 39.5 12.0 0.41 11.6 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90838.1 - 2.4e-05 24.5 2.1 0.032 14.5 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Rpn3_C PF08375.11 EIM90838.1 - 0.032 14.6 3.0 0.45 11.0 1.1 2.3 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal G-alpha PF00503.20 EIM90839.1 - 6.9e-122 407.0 0.0 8.1e-122 406.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM90839.1 - 9.2e-12 44.8 0.0 1.5e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 EIM90839.1 - 0.0013 18.4 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EIM90839.1 - 0.0017 18.6 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EIM90839.1 - 0.008 15.6 0.2 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein Gtr1_RagA PF04670.12 EIM90839.1 - 0.012 15.0 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EIM90839.1 - 0.025 14.3 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EIM90839.1 - 0.03 14.1 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2423 PF10338.9 EIM90839.1 - 3 8.1 6.2 21 5.4 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) Pro_isomerase PF00160.21 EIM90840.1 - 4.5e-49 166.7 0.0 5.2e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F_actin_cap_B PF01115.17 EIM90841.1 - 2.8e-107 357.8 0.0 3.4e-107 357.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit THUMP PF02926.17 EIM90842.1 - 6e-12 45.9 0.8 1.4e-11 44.7 0.8 1.6 1 0 0 1 1 1 1 THUMP domain Adipokin_hormo PF06377.11 EIM90842.1 - 0.0015 18.8 0.2 0.89 10.0 0.0 2.8 3 0 0 3 3 3 2 Adipokinetic hormone PAT1 PF09770.9 EIM90842.1 - 0.0075 14.6 0.1 0.0092 14.3 0.1 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Cwf_Cwc_15 PF04889.12 EIM90842.1 - 0.028 14.2 0.2 0.038 13.7 0.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_trans_4_3 PF12000.8 EIM90843.1 - 0.083 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 4 group Acetate_kinase PF00871.17 EIM90844.1 - 9.3e-86 288.0 0.1 2.5e-85 286.6 0.1 1.6 1 1 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 EIM90845.1 - 8.1e-151 502.0 0.0 1.1e-150 501.6 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 EIM90845.1 - 1.3e-77 259.5 0.0 1.8e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 EIM90845.1 - 9e-77 257.1 0.0 1.6e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 EIM90845.1 - 0.0079 16.0 0.3 0.023 14.5 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 EIM90845.1 - 0.18 11.7 0.2 0.4 10.6 0.2 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain p450 PF00067.22 EIM90846.1 - 6.8e-56 189.9 0.0 1.9e-55 188.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SprA-related PF12118.8 EIM90847.1 - 0.21 10.7 2.8 0.22 10.6 2.8 1.0 1 0 0 1 1 1 0 SprA-related family DnaJ PF00226.31 EIM90848.1 - 3.4e-23 81.5 2.5 3.4e-23 81.5 2.5 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EIM90848.1 - 2.6e-09 37.1 0.9 5e-09 36.2 0.2 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM90848.1 - 5.1e-08 33.1 0.5 5.1e-08 33.1 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EIM90848.1 - 0.0024 18.1 0.4 0.0066 16.8 0.4 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) TAN PF11640.8 EIM90848.1 - 0.063 13.4 0.0 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair zf-C2H2_6 PF13912.6 EIM90848.1 - 0.15 12.1 0.5 0.33 11.0 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger GAS PF13851.6 EIM90848.1 - 3.7 6.9 8.7 7.1 5.9 0.1 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding zf-Tim10_DDP PF02953.15 EIM90849.1 - 1.2e-23 82.5 1.2 1.7e-23 82.0 1.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.11 EIM90849.1 - 0.006 16.6 1.1 0.0072 16.3 1.1 1.1 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein Homeodomain PF00046.29 EIM90850.1 - 1.5e-17 63.2 4.7 3.6e-17 62.0 4.7 1.7 1 0 0 1 1 1 1 Homeodomain U1snRNP70_N PF12220.8 EIM90851.1 - 1.1e-26 93.3 0.4 1.8e-26 92.6 0.4 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EIM90851.1 - 9.4e-15 54.2 0.0 1.8e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UbiA PF01040.18 EIM90852.1 - 4.6e-59 199.8 18.5 4.6e-59 199.8 18.5 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family OrsD PF12013.8 EIM90853.1 - 0.038 14.4 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 EIM90853.1 - 0.066 13.6 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EIM90853.1 - 0.091 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM90853.1 - 0.18 12.3 0.1 0.29 11.6 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type FAM76 PF16046.5 EIM90853.1 - 3.8 6.8 9.6 0.25 10.7 0.7 2.2 2 0 0 2 2 2 0 FAM76 protein Prp18 PF02840.15 EIM90854.1 - 1.6e-61 206.6 0.1 1.6e-61 206.6 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EIM90854.1 - 1.8e-10 40.1 4.4 5.6e-10 38.6 4.4 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CC2-LZ PF16516.5 EIM90854.1 - 0.29 11.5 14.1 57 4.2 9.5 4.3 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Rrn6 PF10214.9 EIM90854.1 - 0.94 7.9 8.1 1.5 7.3 8.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Casc1_N PF15927.5 EIM90854.1 - 1.9 8.2 13.0 6.6 6.4 13.0 1.9 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Macoilin PF09726.9 EIM90854.1 - 4.5 5.7 10.0 12 4.3 10.1 1.7 1 1 0 1 1 1 0 Macoilin family DUF2098 PF09871.9 EIM90854.1 - 7 7.1 7.8 18 5.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) TMEM214 PF10151.9 EIM90854.1 - 8.7 4.7 7.1 13 4.1 7.1 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator COX6B PF02297.17 EIM90855.1 - 4.9e-19 68.3 6.1 5.8e-19 68.1 6.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EIM90855.1 - 0.032 14.3 1.5 0.053 13.6 1.5 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydrolase_1 PF00561.20 EIM90856.1 - 3.1e-10 40.1 0.0 2.1e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM90856.1 - 1e-05 26.2 0.0 1.5e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EIM90856.1 - 7.9e-05 22.6 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EIM90856.1 - 0.00057 19.4 0.0 0.00093 18.7 0.0 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EIM90856.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein LIP PF03583.14 EIM90856.1 - 0.17 11.2 0.1 0.39 10.0 0.1 1.5 1 1 1 2 2 2 0 Secretory lipase Hydrolase_4 PF12146.8 EIM90856.1 - 0.18 11.0 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Citrate_synt PF00285.21 EIM90857.1 - 1.7e-98 330.0 0.0 2.2e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Transglut_core PF01841.19 EIM90858.1 - 8.4e-11 42.3 0.1 2.1e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.12 EIM90858.1 - 0.0031 17.0 0.0 0.026 14.0 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like domain Peptidase_C2 PF00648.21 EIM90859.1 - 1.2e-68 231.4 3.5 7.2e-68 228.8 3.5 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Methyltransf_31 PF13847.6 EIM90860.1 - 3.2e-14 53.0 0.0 4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM90860.1 - 3.6e-05 24.4 0.0 6.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM90860.1 - 8.2e-05 22.2 0.0 0.00027 20.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EIM90860.1 - 9.7e-05 22.3 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM90860.1 - 0.00011 22.9 0.0 0.0002 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM90860.1 - 0.0029 18.2 0.0 0.0081 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EIM90860.1 - 0.13 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3421 PF11901.8 EIM90861.1 - 9.6e-29 99.7 0.0 1.2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) MIF4G PF02854.19 EIM90862.1 - 6.2e-32 111.0 4.2 9.4e-32 110.4 4.2 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EIM90862.1 - 1e-20 73.8 0.0 4.2e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 MA3 domain LST1 PF05083.13 EIM90862.1 - 0.23 11.8 0.8 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 LST-1 protein DNA_pol_phi PF04931.13 EIM90862.1 - 0.28 9.3 15.2 1.6 6.7 0.3 2.5 2 0 0 2 2 2 0 DNA polymerase phi Pyr_redox_3 PF13738.6 EIM90863.1 - 4.9e-24 85.1 0.0 2.2e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIM90863.1 - 1.5e-19 69.8 0.0 1.2e-12 47.1 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EIM90863.1 - 2.8e-13 49.8 0.0 8.7e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM90863.1 - 7.7e-12 45.0 0.0 4.6e-07 29.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EIM90863.1 - 2.8e-07 30.7 0.3 0.00024 21.2 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EIM90863.1 - 5.7e-05 22.5 0.2 0.00032 20.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EIM90863.1 - 0.00013 22.1 0.0 0.00048 20.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EIM90863.1 - 0.00026 21.2 0.2 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.27 EIM90863.1 - 0.00041 20.9 0.9 0.9 10.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM90863.1 - 0.0011 18.6 0.2 0.037 13.6 0.1 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.16 EIM90863.1 - 0.0013 18.4 0.0 0.025 14.2 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EIM90863.1 - 0.013 14.8 0.1 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EIM90863.1 - 0.019 13.7 0.1 0.078 11.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 EIM90863.1 - 0.025 15.0 0.0 2 8.9 0.1 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EIM90863.1 - 0.025 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EIM90863.1 - 0.062 12.4 0.1 0.67 9.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.21 EIM90863.1 - 0.11 11.9 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.6 EIM90863.1 - 0.12 12.4 0.0 4 7.4 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 EIM90863.1 - 0.12 11.7 0.1 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 EIM90864.1 - 6.1e-33 114.2 25.3 6.1e-33 114.2 25.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM90864.1 - 4.4e-12 45.6 7.1 4.4e-12 45.6 7.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Sm_multidrug_ex PF06695.11 EIM90864.1 - 1.3 9.7 7.8 16 6.2 0.2 3.8 4 0 0 4 4 4 0 Putative small multi-drug export protein TRI12 PF06609.13 EIM90864.1 - 4.2 5.6 13.1 0.034 12.6 3.7 2.2 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Metallophos PF00149.28 EIM90865.1 - 3.5e-36 125.6 0.4 5.1e-36 125.1 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIM90865.1 - 0.00074 19.9 0.1 0.0015 18.9 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Cpn60_TCP1 PF00118.24 EIM90866.1 - 4.3e-157 523.7 1.6 4.9e-157 523.5 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Abhydrolase_1 PF00561.20 EIM90867.1 - 2.7e-37 128.8 0.0 3.4e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM90867.1 - 6.5e-13 48.5 0.0 1.4e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIM90867.1 - 6.1e-07 30.3 0.0 7.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIM90867.1 - 0.018 14.5 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family EHN PF06441.12 EIM90867.1 - 0.05 14.0 0.2 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Ndr PF03096.14 EIM90867.1 - 0.071 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ser_hydrolase PF06821.13 EIM90867.1 - 0.086 12.7 0.3 2.5 7.9 0.0 2.4 3 0 0 3 3 3 0 Serine hydrolase Peptidase_S28 PF05577.12 EIM90867.1 - 0.095 11.5 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 EIM90867.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein CRAL_TRIO PF00650.20 EIM90868.1 - 2.5e-28 98.8 0.0 3.6e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIM90868.1 - 6.4e-17 61.5 0.6 1.4e-16 60.4 0.6 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EIM90868.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain FAD_binding_3 PF01494.19 EIM90869.1 - 9.1e-20 71.2 0.1 1.6e-19 70.4 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM90869.1 - 0.0033 17.6 0.1 0.01 16.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ntox4 PF15541.6 EIM90869.1 - 0.034 14.5 0.0 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial toxin 4 Sad1_UNC PF07738.13 EIM90870.1 - 1.6e-25 89.7 0.0 9e-13 48.4 0.0 2.6 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal APG6_N PF17675.1 EIM90872.1 - 0.0056 17.2 2.3 0.0059 17.1 0.8 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region Filament PF00038.21 EIM90872.1 - 0.025 14.2 2.0 0.045 13.3 2.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein CENP-H PF05837.12 EIM90872.1 - 0.15 12.5 4.0 0.25 11.7 1.6 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DHR10 PF18595.1 EIM90872.1 - 0.31 11.1 9.4 0.047 13.8 4.9 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 EIM90872.1 - 0.35 11.2 1.7 2.3 8.6 0.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSNAXIP1_N PF15739.5 EIM90872.1 - 0.42 11.0 2.9 0.95 9.9 2.9 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus ATG16 PF08614.11 EIM90872.1 - 0.98 9.6 14.8 0.048 13.9 6.8 2.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EIM90872.1 - 2.9 7.7 5.7 38 4.1 0.0 2.8 2 1 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 EIM90873.1 - 0.0066 16.3 0.2 0.017 15.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like Jacalin PF01419.17 EIM90874.1 - 0.00027 20.9 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Aldo_ket_red PF00248.21 EIM90875.1 - 1.4e-45 155.8 0.0 1.1e-34 120.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Yip1 PF04893.17 EIM90877.1 - 4.6e-14 52.5 17.6 6.8e-14 52.0 17.6 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EIM90877.1 - 0.23 11.2 11.0 0.32 10.8 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) AAA PF00004.29 EIM90878.1 - 2.4e-41 141.2 0.0 4.1e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EIM90878.1 - 2.3e-11 43.5 0.0 4.6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EIM90878.1 - 6.1e-09 35.6 0.9 1.1e-08 34.7 0.9 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EIM90878.1 - 5.5e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EIM90878.1 - 4.3e-05 23.8 0.2 0.015 15.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EIM90878.1 - 4.7e-05 22.7 0.0 8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EIM90878.1 - 0.00024 21.5 0.2 0.0087 16.5 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EIM90878.1 - 0.00029 20.8 0.3 0.0017 18.3 0.3 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIM90878.1 - 0.00066 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EIM90878.1 - 0.0066 16.3 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EIM90878.1 - 0.0066 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EIM90878.1 - 0.0068 15.8 0.1 0.25 10.6 0.1 2.3 1 1 1 2 2 2 1 KaiC Prot_ATP_OB_N PF17758.1 EIM90878.1 - 0.0078 15.8 0.3 0.046 13.4 0.0 2.4 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 EIM90878.1 - 0.0084 16.4 0.2 0.096 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIM90878.1 - 0.012 16.2 0.6 0.019 15.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EIM90878.1 - 0.025 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIM90878.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EIM90878.1 - 0.062 13.2 0.1 0.8 9.6 0.1 2.4 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 EIM90878.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 EIM90878.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EIM90878.1 - 0.094 12.3 0.5 2.8 7.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EIM90878.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EIM90878.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EIM90878.1 - 0.12 12.1 0.3 0.35 10.6 0.3 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EIM90878.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EIM90878.1 - 0.2 11.3 0.4 0.46 10.2 0.4 1.6 1 1 0 1 1 1 0 AAA domain Citrate_synt PF00285.21 EIM90879.1 - 4e-119 397.9 0.0 4.8e-119 397.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Brix PF04427.18 EIM90880.1 - 9.4e-41 140.0 0.3 1.3e-40 139.6 0.3 1.2 1 0 0 1 1 1 1 Brix domain Gon7 PF08738.10 EIM90880.1 - 0.062 13.4 0.7 0.15 12.2 0.7 1.6 1 0 0 1 1 1 0 Gon7 family F-box-like PF12937.7 EIM90881.1 - 1.1e-08 34.9 2.8 1.1e-08 34.8 1.4 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM90881.1 - 8e-07 28.8 1.8 3e-06 26.9 1.0 2.4 3 0 0 3 3 3 1 F-box domain DUF883 PF05957.13 EIM90882.1 - 0.65 10.6 7.2 3.7 8.2 3.3 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Epimerase PF01370.21 EIM90883.1 - 8.4e-05 22.1 0.0 0.00042 19.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF3504 PF12012.8 EIM90884.1 - 0.46 10.4 0.1 0.46 10.4 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3504) Dioxygenase_C PF00775.21 EIM90885.1 - 5.4e-07 29.2 0.1 9.8e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Abhydrolase_6 PF12697.7 EIM90889.1 - 5.9e-15 56.5 0.0 7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM90889.1 - 7e-15 55.4 0.2 3e-14 53.3 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EIM90889.1 - 7.7e-08 32.3 0.1 1.3e-06 28.3 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EIM90889.1 - 8.4e-08 31.8 1.8 2.2e-07 30.4 0.3 2.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EIM90889.1 - 9.6e-07 29.1 0.0 1.2e-06 28.9 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 EIM90889.1 - 5.4e-05 22.8 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 EIM90889.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EIM90889.1 - 0.0023 16.9 0.3 0.0046 15.9 0.2 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme DUF2048 PF09752.9 EIM90889.1 - 0.0031 16.7 0.3 0.023 13.8 0.3 2.1 1 1 0 1 1 1 1 Abhydrolase domain containing 18 Chlorophyllase PF07224.11 EIM90889.1 - 0.007 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.25 EIM90889.1 - 0.013 15.3 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 EIM90889.1 - 0.07 13.0 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 EIM90889.1 - 0.079 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.20 EIM90889.1 - 0.18 11.4 0.3 0.29 10.7 0.3 1.3 1 0 0 1 1 1 0 Putative esterase RF-1 PF00472.20 EIM90891.1 - 7.6e-23 80.7 0.1 1.1e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 RF-1 domain Tropomyosin_1 PF12718.7 EIM90892.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.0 2 0 0 2 2 2 0 Tropomyosin like FlaF PF07309.11 EIM90892.1 - 2.2 8.3 5.3 0.33 11.0 0.9 1.8 2 0 0 2 2 2 0 Flagellar protein FlaF DcpS_C PF11969.8 EIM90893.1 - 4.7e-25 88.3 0.7 5.7e-25 88.0 0.7 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EIM90893.1 - 1.9e-13 51.0 0.8 2.8e-13 50.4 0.8 1.2 1 0 0 1 1 1 1 HIT domain BTB PF00651.31 EIM90897.1 - 0.008 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Forkhead PF00250.18 EIM90899.1 - 7e-28 96.7 0.0 8.3e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain RNase_HII PF01351.18 EIM90900.1 - 1.4e-45 155.6 0.0 5.8e-43 147.0 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease HII Aldo_ket_red PF00248.21 EIM90901.1 - 8e-42 143.4 0.0 1.2e-20 73.9 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family DUF3613 PF12266.8 EIM90902.1 - 0.014 15.1 1.0 0.027 14.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Trypan_PARP PF05887.11 EIM90903.1 - 0.016 15.2 0.6 0.034 14.1 0.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Beta-lactamase PF00144.24 EIM90904.1 - 1e-32 113.7 0.4 1.4e-32 113.3 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 EIM90905.1 - 1.3e-15 57.2 32.3 3e-15 56.0 31.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EIM90905.1 - 6.6e-06 25.9 1.9 6.6e-06 25.9 1.9 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EIM90905.1 - 1.7e-05 23.9 6.5 1.7e-05 23.9 6.5 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_43 PF04616.14 EIM90906.1 - 1.3e-22 80.5 22.7 5.3e-10 39.1 1.5 3.2 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 IL4_i_Ig PF18258.1 EIM90906.1 - 0.2 11.9 0.8 0.77 10.0 0.8 2.0 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain Peptidase_M48 PF01435.18 EIM90907.1 - 2.6e-13 50.2 0.0 5.7e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 EIM90907.1 - 0.067 12.8 0.7 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) DUF4594 PF15266.6 EIM90907.1 - 1.8 8.9 8.2 0.26 11.6 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4594) Dioxygenase_C PF00775.21 EIM90908.1 - 4.4e-07 29.5 0.1 8.5e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.21 EIM90909.1 - 4.7e-07 29.4 0.0 7.7e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Dioxygenase LZ3wCH PF18517.1 EIM90910.1 - 0.01 15.9 0.0 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Na_Ca_ex PF01699.24 EIM90911.1 - 2.5e-24 86.0 29.4 7.8e-14 51.9 15.4 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein COX5B PF01215.19 EIM90912.1 - 2.8e-41 140.2 0.0 3.8e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EIM90912.1 - 0.0046 17.0 0.1 0.0077 16.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain Beta-lactamase PF00144.24 EIM90913.1 - 6.2e-32 111.1 0.4 8.9e-32 110.6 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase DPBB_1 PF03330.18 EIM90914.1 - 2.7e-05 24.3 0.1 5.6e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM90914.1 - 0.002 18.0 0.1 0.0031 17.4 0.1 1.5 1 1 0 1 1 1 1 Barwin family Svf1_C PF17187.4 EIM90915.1 - 7.4e-47 159.2 0.0 1.2e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EIM90915.1 - 2.6e-43 147.9 0.0 3.7e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain TPR_19 PF14559.6 EIM90916.1 - 2e-11 44.2 6.8 5.6e-05 23.6 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIM90916.1 - 8.8e-09 34.8 0.5 9.5 6.6 0.5 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM90916.1 - 1.9e-08 34.5 1.9 0.09 13.1 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIM90916.1 - 2.7e-08 33.6 0.0 0.024 15.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM90916.1 - 4.3e-08 33.7 4.4 0.0029 18.2 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM90916.1 - 2.2e-07 31.1 10.1 2.6 9.1 0.1 6.1 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EIM90916.1 - 6.3e-07 28.9 0.0 1.5 8.8 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM90916.1 - 1.1e-05 25.3 0.2 2.9 8.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIM90916.1 - 0.00012 21.8 0.2 0.37 10.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIM90916.1 - 0.00016 22.1 3.4 2.3 9.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM90916.1 - 0.00092 19.1 2.8 7.1 6.9 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 EIM90916.1 - 0.0048 16.3 0.1 2 7.8 0.0 2.6 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_20 PF14561.6 EIM90916.1 - 0.015 15.7 3.4 0.097 13.0 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM90916.1 - 0.018 15.2 0.2 11 6.4 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EIM90916.1 - 0.034 14.2 0.2 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 EIM90916.1 - 0.066 13.4 3.4 0.8 9.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM90916.1 - 0.08 12.6 0.0 12 5.7 0.0 3.4 3 0 0 3 3 3 0 TPR repeat Fis1_TPR_C PF14853.6 EIM90916.1 - 0.11 12.5 0.2 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EIM90916.1 - 0.13 12.9 0.0 12 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTB PF00651.31 EIM90917.1 - 0.055 13.7 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF2142 PF09913.9 EIM90918.1 - 0.0065 15.4 1.0 0.0075 15.2 1.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) GPI-anchored PF10342.9 EIM90921.1 - 0.02 15.6 0.3 0.051 14.3 0.4 1.6 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-CCHC PF00098.23 EIM90922.1 - 3.6e-07 29.9 9.7 0.00032 20.7 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-BED PF02892.15 EIM90922.1 - 0.15 12.1 2.7 0.76 9.9 0.3 2.4 2 0 0 2 2 2 0 BED zinc finger zf-CCHC_4 PF14392.6 EIM90922.1 - 0.34 10.7 9.0 2.8 7.8 1.8 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 EIM90922.1 - 8.3 6.3 12.1 1.5 8.7 0.5 2.9 3 0 0 3 3 3 0 Zinc knuckle Na_Ca_ex PF01699.24 EIM90923.1 - 1.6e-43 148.3 45.5 1.7e-26 93.0 15.4 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DPBB_1 PF03330.18 EIM90924.1 - 0.00021 21.5 0.0 0.00025 21.3 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIM90924.1 - 0.015 15.1 0.0 0.058 13.2 0.0 1.8 1 1 0 1 1 1 0 Barwin family TPK_catalytic PF04263.16 EIM90925.1 - 2.9e-35 120.9 0.0 3.9e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EIM90925.1 - 4.3e-19 68.0 0.3 9e-19 67.0 0.3 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SRF-TF PF00319.18 EIM90926.1 - 5.5e-22 77.0 0.1 8.5e-22 76.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Isochorismatase PF00857.20 EIM90928.1 - 8.2e-13 48.9 0.0 1.2e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Pkinase PF00069.25 EIM90930.1 - 3.4e-40 138.1 0.0 4.9e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM90930.1 - 4.9e-18 65.4 0.0 6.8e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM90930.1 - 0.00079 19.4 0.5 0.00079 19.4 0.5 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM90930.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIM90930.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EIM90930.1 - 0.1 12.2 0.1 0.82 9.2 0.0 2.0 2 0 0 2 2 2 0 RIO1 family CbiM PF01891.16 EIM90931.1 - 0.39 10.5 15.5 0.022 14.6 5.6 2.7 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region SPC25 PF06703.11 EIM90931.1 - 3.1 7.6 7.9 1.4 8.7 1.6 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) WD40 PF00400.32 EIM90932.1 - 7e-32 109.0 15.2 1.6e-06 28.8 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90932.1 - 3.6e-12 46.4 0.1 1.2e-05 25.5 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM90932.1 - 0.0035 16.3 0.0 0.055 12.4 0.0 2.6 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIM90932.1 - 0.031 13.6 0.0 4.2 6.6 0.0 3.1 4 0 0 4 4 4 0 WD40-like domain WDCP PF15390.6 EIM90932.1 - 0.073 11.5 0.0 0.096 11.1 0.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Glyoxal_oxid_N PF07250.11 EIM90932.1 - 0.18 10.9 0.0 0.37 9.9 0.0 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 EIM90932.1 - 0.23 12.0 17.1 6 7.5 1.2 5.9 6 0 0 6 6 6 0 PQQ-like domain F-box-like PF12937.7 EIM90933.1 - 7.8e-07 28.9 0.2 7.8e-07 28.9 0.2 2.5 3 0 0 3 3 3 1 F-box-like zf-RING_5 PF14634.6 EIM90934.1 - 0.022 14.7 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Tetraspanin PF00335.20 EIM90935.1 - 7.6e-09 35.6 13.1 1e-08 35.2 13.1 1.1 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.14 EIM90935.1 - 0.018 14.2 0.4 0.035 13.3 0.4 1.4 1 0 0 1 1 1 0 Iron permease FTR1 family DUF3278 PF11683.8 EIM90935.1 - 0.037 14.1 0.1 0.076 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF1422 PF07226.11 EIM90935.1 - 0.15 12.0 2.3 9.5 6.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) COMPASS-Shg1 PF05205.12 EIM90936.1 - 2e-13 50.9 0.0 3.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 BNIP2 PF12496.8 EIM90936.1 - 5.4 7.5 13.9 4 7.9 12.5 1.7 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Cyanate_lyase PF02560.14 EIM90937.1 - 3.7e-33 113.2 0.0 5.3e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EIM90937.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HDOD PF08668.12 EIM90937.1 - 0.13 11.7 0.0 2.3 7.7 0.0 2.0 1 1 1 2 2 2 0 HDOD domain Complex1_LYR_2 PF13233.6 EIM90938.1 - 2.9e-19 69.6 0.1 3.8e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EIM90938.1 - 2.8e-12 46.5 0.1 4.4e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) IL10 PF00726.17 EIM90938.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Interleukin 10 Complex1_LYR_1 PF13232.6 EIM90938.1 - 0.052 14.1 0.0 0.083 13.5 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Aldo_ket_red PF00248.21 EIM90939.1 - 1.3e-38 132.9 0.1 1.5e-36 126.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family 7TMR-DISMED2 PF07696.11 EIM90939.1 - 0.059 13.4 0.1 11 6.1 0.0 2.3 1 1 1 2 2 2 0 7TMR-DISM extracellular 2 Dev_Cell_Death PF10539.9 EIM90939.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Development and cell death domain DUF4604 PF15377.6 EIM90940.1 - 2.1e-29 103.1 18.1 2.6e-29 102.9 18.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Arv1 PF04161.13 EIM90941.1 - 3.5e-38 131.9 0.0 4.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Arv1-like family Gti1_Pac2 PF09729.9 EIM90942.1 - 6.8e-34 117.5 0.5 2.1e-25 89.8 0.0 3.1 2 1 1 3 3 3 2 Gti1/Pac2 family Cellulase PF00150.18 EIM90943.1 - 2.4e-14 53.4 4.4 4.1e-14 52.7 3.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TFIIA PF03153.13 EIM90944.1 - 9.2 6.1 13.2 17 5.3 13.2 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_35 PF01301.19 EIM90945.1 - 2.9e-79 267.0 0.9 4.3e-79 266.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EIM90945.1 - 2.2e-57 192.5 5.0 8.2e-35 119.8 0.1 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EIM90945.1 - 8.9e-33 113.6 1.6 1.6e-32 112.8 1.6 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EIM90945.1 - 2.6e-18 65.3 0.2 2.4e-17 62.3 0.1 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 EIM90945.1 - 1.9e-05 24.2 0.2 9.7e-05 21.9 0.2 1.9 1 1 0 1 1 1 1 Beta-galactosidase Tfb2 PF03849.14 EIM90946.1 - 1.5e-137 458.4 0.0 1.7e-137 458.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EIM90946.1 - 2.8e-25 88.5 0.1 5.9e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EIM90946.1 - 0.00027 21.1 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.24 EIM90947.1 - 2.2e-33 115.8 36.8 1.6e-19 70.1 10.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EIM90947.1 - 1.7e-17 63.4 50.9 3.1e-13 49.4 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 EIM90948.1 - 0.00047 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPT2 PF08243.11 EIM90949.1 - 1.8e-20 73.5 12.3 1.8e-20 73.5 12.3 4.4 2 1 1 3 3 3 1 SPT2 chromatin protein MFS_1 PF07690.16 EIM90950.1 - 1.5e-25 89.9 37.2 1.1e-16 60.8 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM90950.1 - 5.7e-09 35.3 13.8 2.7e-08 33.1 0.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Amidohydro_1 PF01979.20 EIM90951.1 - 8.7e-63 212.7 1.1 1.4e-62 212.0 1.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EIM90951.1 - 2.3e-55 186.1 2.3 4.5e-55 185.1 2.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EIM90951.1 - 6.4e-42 141.6 0.5 1.5e-41 140.4 0.1 1.9 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 EIM90951.1 - 6.5e-41 138.7 0.1 1.8e-40 137.2 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EIM90951.1 - 0.0049 16.4 0.1 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family CHORD PF04968.12 EIM90952.1 - 0.18 12.5 0.3 0.18 12.5 0.3 2.7 2 1 0 2 2 2 0 CHORD MFS_1 PF07690.16 EIM90953.1 - 1.4e-27 96.6 27.2 1.4e-27 96.6 27.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM90953.1 - 0.072 11.9 29.2 0.4 9.5 29.2 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter Cupin_1 PF00190.22 EIM90954.1 - 9e-44 148.7 0.1 3.3e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EIM90954.1 - 1.9e-29 101.2 0.4 3.2e-14 52.4 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EIM90954.1 - 1.6e-09 37.3 0.0 0.00056 19.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EIM90954.1 - 1e-06 28.7 0.4 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain ARD PF03079.14 EIM90954.1 - 4.9e-06 26.8 0.0 0.0057 16.9 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family MannoseP_isomer PF01050.18 EIM90954.1 - 3.9e-05 23.6 0.0 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 EIM90954.1 - 0.00041 19.9 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein 3-HAO PF06052.12 EIM90954.1 - 0.00076 19.1 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase A_deaminase PF00962.22 EIM90955.1 - 2.8e-39 135.4 0.0 3.2e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EIM90955.1 - 0.00012 21.5 0.2 0.00027 20.4 0.2 1.7 1 1 0 1 1 1 1 Amidohydrolase family KIF1B PF12423.8 EIM90955.1 - 0.27 11.7 0.7 2.2 8.8 0.7 2.4 1 1 0 1 1 1 0 Kinesin protein 1B MFS_1 PF07690.16 EIM90956.1 - 4.9e-32 111.2 34.2 6e-32 110.9 34.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EIM90956.1 - 2e-05 24.1 7.7 2e-05 24.1 7.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4112 PF13430.6 EIM90958.1 - 2.9e-30 104.6 0.1 3.8e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF3275 PF11679.8 EIM90960.1 - 0.57 10.1 5.4 1 9.3 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) TFIIA PF03153.13 EIM90960.1 - 9.7 6.1 19.8 14 5.6 19.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tubulin PF00091.25 EIM90961.1 - 3.9e-64 216.5 0.0 5.6e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIM90961.1 - 2.6e-36 124.5 0.0 4.6e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EIM90961.1 - 2.5e-05 24.6 0.1 6.3e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EIM90961.1 - 0.00015 21.5 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Response_reg PF00072.24 EIM90962.1 - 3e-20 72.5 0.0 1.5e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EIM90962.1 - 1e-16 61.4 0.1 5.7e-16 59.0 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EIM90962.1 - 8.3e-14 51.4 0.1 2.4e-13 49.9 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EIM90962.1 - 9.6e-08 32.7 0.0 0.0023 18.6 0.0 3.0 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 EIM90962.1 - 0.0052 17.1 0.0 3.7 7.9 0.0 2.9 2 0 0 2 2 2 2 GAF domain CTP_transf_1 PF01148.20 EIM90963.1 - 0.0061 16.3 4.1 0.0061 16.3 4.1 2.3 2 0 0 2 2 2 1 Cytidylyltransferase family Alpha_kinase PF02816.18 EIM90964.1 - 2e-15 57.4 0.0 2.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family UDG PF03167.19 EIM90965.1 - 1.8e-20 73.5 0.0 2.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Foie-gras_1 PF11817.8 EIM90965.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 bZIP_1 PF00170.21 EIM90966.1 - 3.3e-05 23.9 4.1 5.6e-05 23.2 4.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EIM90966.1 - 0.0034 17.4 2.6 0.0073 16.4 2.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.13 EIM90966.1 - 0.022 14.0 0.3 0.036 13.3 0.3 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region BMFP PF04380.13 EIM90966.1 - 0.11 13.0 3.9 0.19 12.2 3.9 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity WD40_alt PF14077.6 EIM90966.1 - 0.21 11.5 0.5 0.35 10.8 0.5 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif Nnf1 PF03980.14 EIM90966.1 - 0.73 10.2 5.3 0.26 11.7 0.5 2.5 3 0 0 3 3 3 0 Nnf1 ERCC3_RAD25_C PF16203.5 EIM90967.1 - 1.2e-124 414.5 0.4 2.3e-124 413.5 0.2 1.5 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EIM90967.1 - 3.3e-37 127.5 0.0 7.3e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM90967.1 - 6.1e-16 58.9 0.0 1.3e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM90967.1 - 6.9e-11 42.5 0.1 2.2e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EIM90967.1 - 2.5e-09 36.3 0.0 3.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SF1-HH PF16275.5 EIM90968.1 - 2.3e-36 124.6 2.4 3.9e-36 123.8 2.4 1.4 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EIM90968.1 - 7.8e-11 41.5 11.3 4.4e-05 23.3 3.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EIM90968.1 - 3e-06 27.1 4.9 0.00097 19.1 1.3 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EIM90968.1 - 9.9e-06 25.3 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 KH domain CCDC-167 PF15188.6 EIM90968.1 - 0.0017 18.7 2.6 1.5 9.2 0.2 2.5 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 zf-CCHC_4 PF14392.6 EIM90968.1 - 0.0037 17.0 7.5 0.2 11.4 0.6 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EIM90968.1 - 0.014 15.2 8.8 0.26 11.2 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 EIM90968.1 - 0.11 12.8 3.6 0.24 11.7 3.6 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DnaJ_CXXCXGXG PF00684.19 EIM90968.1 - 0.15 12.4 4.5 0.31 11.4 4.5 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.6 EIM90968.1 - 0.88 9.5 9.8 0.17 11.7 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle Methyltr_RsmB-F PF01189.17 EIM90969.1 - 6.6e-30 104.2 0.0 1.2e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Cons_hypoth95 PF03602.15 EIM90969.1 - 0.018 14.7 0.1 0.044 13.4 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 HMw1_D2 PF18254.1 EIM90969.1 - 0.1 13.0 0.3 0.27 11.6 0.3 1.6 1 0 0 1 1 1 0 HMW1 domain 2 DnaJ_C PF01556.18 EIM90970.1 - 1.8e-36 125.5 0.0 2.5e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIM90970.1 - 6e-24 84.0 0.5 1e-23 83.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIM90970.1 - 1.3e-11 44.7 17.1 2.1e-11 44.0 17.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EIM90970.1 - 0.00029 20.7 10.4 0.08 12.9 3.0 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EIM90970.1 - 0.12 12.4 7.2 1 9.4 1.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EIM90970.1 - 4.6 7.3 7.9 14 5.8 1.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon 7tm_1 PF00001.21 EIM90971.1 - 0.0056 16.0 6.3 0.0092 15.3 6.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ras PF00071.22 EIM90972.1 - 2.2e-58 196.4 0.1 2.5e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM90972.1 - 1.7e-20 73.4 0.0 2.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM90972.1 - 6.5e-09 35.5 0.0 7.7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIM90972.1 - 2.9e-05 23.7 0.1 6.6e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIM90972.1 - 0.00013 21.9 0.0 0.27 11.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EIM90972.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM90972.1 - 0.019 14.5 0.1 0.047 13.2 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EIM90972.1 - 0.068 12.9 1.9 0.59 9.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 EIM90972.1 - 0.079 12.1 0.5 1.9 7.6 0.4 2.0 1 1 0 2 2 2 0 G-protein alpha subunit Ser_hydrolase PF06821.13 EIM90972.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase CIA30 PF08547.12 EIM90973.1 - 2.8e-23 82.7 0.0 3.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) KDZ PF18758.1 EIM90975.1 - 1.4e-24 86.9 0.0 1.8e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MarC PF01914.17 EIM90975.1 - 0.082 12.3 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein NARP1 PF12569.8 EIM90976.1 - 0.11 11.4 9.1 0.11 11.3 9.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 EIM90976.1 - 1.2 9.6 7.1 1.7 9.1 7.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 EIM90976.1 - 1.5 7.5 6.3 1.7 7.4 6.3 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EIM90976.1 - 3.4 6.4 10.0 3.7 6.2 10.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDRGK PF09756.9 EIM90976.1 - 4 7.0 15.8 4.5 6.8 15.8 1.1 1 0 0 1 1 1 0 DDRGK domain PIEZO PF15917.5 EIM90976.1 - 4.9 6.6 9.6 5.9 6.3 9.6 1.1 1 0 0 1 1 1 0 Piezo RR_TM4-6 PF06459.12 EIM90976.1 - 8.1 6.2 12.8 10 5.8 12.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fungal_trans_2 PF11951.8 EIM90977.1 - 0.0024 16.8 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_3 PF13358.6 EIM90978.1 - 1.4e-07 31.4 0.0 1.5e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4358 PF14270.6 EIM90978.1 - 0.085 13.2 0.0 0.099 12.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) DDE_3 PF13358.6 EIM90979.1 - 9.1e-08 32.0 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotran_gag_2 PF14223.6 EIM90981.1 - 1.1e-19 70.4 0.4 1.4e-19 70.1 0.4 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 EIM90983.1 - 3.5e-08 33.6 0.0 6.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 EIM90983.1 - 3.1e-06 27.0 0.0 7.8e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) DDE_Tnp_4 PF13359.6 EIM90989.1 - 0.0021 17.8 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EIM90989.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Dimer_Tnp_hAT PF05699.14 EIM90990.1 - 8.8e-14 51.1 0.1 1.7e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region XH PF03469.14 EIM90990.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 XH domain DUF5551 PF17705.1 EIM90991.1 - 0.055 13.1 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5551) KDZ PF18758.1 EIM90992.1 - 2.4e-56 190.9 0.0 3.6e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EIM90992.1 - 2.7e-44 149.7 0.1 2.9e-43 146.4 0.0 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EIM90992.1 - 0.00011 22.3 0.1 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases AD PF09793.9 EIM90992.1 - 0.036 14.2 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 Anticodon-binding domain zf-B_box PF00643.24 EIM90992.1 - 1.1 9.5 4.8 2.3 8.5 4.8 1.6 1 0 0 1 1 1 0 B-box zinc finger 2OG-FeII_Oxy_3 PF13640.6 EIM90993.1 - 0.019 15.8 0.0 0.055 14.4 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Cauli_VI PF01693.16 EIM90995.1 - 1.3e-19 70.2 1.2 8.6e-06 26.0 0.2 4.2 4 1 1 5 5 5 3 Caulimovirus viroplasmin BUD22 PF09073.10 EIM90995.1 - 0.56 9.5 2.9 0.84 8.9 2.9 1.1 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 EIM90995.1 - 0.67 9.8 3.9 0.75 9.6 3.9 1.1 1 0 0 1 1 1 0 SPX domain HMG_box PF00505.19 EIM90996.1 - 0.079 13.4 0.5 0.17 12.3 0.5 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Phage_RpbA PF10789.9 EIM90997.1 - 0.0069 16.4 0.7 0.009 16.1 0.7 1.2 1 0 0 1 1 1 1 Phage RNA polymerase binding, RpbA Phospholip_A2_3 PF09056.11 EIM90997.1 - 0.0077 16.8 0.3 0.0085 16.7 0.3 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 RAG2_PHD PF13341.6 EIM90997.1 - 0.084 12.9 0.0 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 RAG2 PHD domain ABA_WDS PF02496.16 EIM90998.1 - 0.05 14.1 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 ABA/WDS induced protein Ost5 PF05251.12 EIM90998.1 - 0.065 13.5 0.2 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 WD40 PF00400.32 EIM90999.1 - 2.3e-19 69.3 0.1 0.0026 18.6 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM90999.1 - 1.7e-07 31.4 0.0 0.63 10.4 0.0 4.3 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb5_C PF01191.19 EIM91000.1 - 8.6e-31 105.6 0.4 1.4e-30 104.9 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EIM91000.1 - 1.7e-16 60.5 0.0 2.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Terpene_synth_C PF03936.16 EIM91001.1 - 0.0026 17.2 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF5014 PF16406.5 EIM91001.1 - 0.049 13.9 0.3 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5014) Pyr_redox_2 PF07992.14 EIM91002.1 - 7.2e-52 176.4 0.5 9.9e-52 176.0 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EIM91002.1 - 4.6e-18 64.9 0.0 1.2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EIM91002.1 - 1.7e-11 44.5 1.0 6.4e-09 36.3 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EIM91002.1 - 1.2e-07 32.1 0.0 3.7e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal Pyr_redox_3 PF13738.6 EIM91002.1 - 6.3e-07 28.9 0.5 3.5e-06 26.5 0.2 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM91002.1 - 0.00013 21.3 0.1 0.014 14.5 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EIM91002.1 - 0.0019 17.0 0.1 0.69 8.5 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 EIM91002.1 - 0.0053 16.8 0.1 2.4 8.2 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Glyco_hydro_3_C PF01915.22 EIM91002.1 - 0.018 15.0 0.0 7.6 6.4 0.0 2.7 2 1 1 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain NAD_binding_7 PF13241.6 EIM91002.1 - 0.061 13.8 0.0 0.21 12.1 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Cys_Met_Meta_PP PF01053.20 EIM91003.1 - 9.7e-129 429.2 0.0 1.2e-128 428.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 EIM91003.1 - 6.7e-17 61.5 0.0 3.4e-16 59.2 0.0 2.3 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EIM91003.1 - 2.1e-06 28.0 0.1 9.2e-06 25.9 0.1 2.2 1 0 0 1 1 1 1 GHMP kinases C terminal Aminotran_1_2 PF00155.21 EIM91003.1 - 8.7e-06 25.1 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIM91003.1 - 3.7e-05 23.2 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EIM91003.1 - 0.00027 19.6 0.0 0.00086 17.9 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.13 EIM91003.1 - 0.00071 18.7 0.0 0.0087 15.1 0.0 2.1 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase GalKase_gal_bdg PF10509.9 EIM91003.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Beta_elim_lyase PF01212.21 EIM91003.1 - 0.098 11.9 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase zf-HIT PF04438.16 EIM91004.1 - 7.9e-09 35.2 9.0 1.3e-08 34.5 9.0 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EIM91004.1 - 7 6.8 13.1 12 6.1 13.1 1.4 1 0 0 1 1 1 0 MYND finger HMGL-like PF00682.19 EIM91005.1 - 1.4e-80 270.7 1.1 2e-80 270.2 1.1 1.2 1 0 0 1 1 1 1 HMGL-like Turandot PF07240.11 EIM91005.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot ECH_1 PF00378.20 EIM91006.1 - 1.7e-23 83.2 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIM91006.1 - 3e-05 23.7 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Sugar_tr PF00083.24 EIM91007.1 - 5e-72 243.2 23.6 5.7e-72 243.0 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM91007.1 - 1.6e-26 93.1 47.9 1.9e-23 82.9 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EIM91008.1 - 6.7e-49 166.6 0.0 1.5e-48 165.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91008.1 - 7.8e-18 64.7 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM91008.1 - 0.0033 16.8 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EIM91008.1 - 0.055 13.1 0.6 0.4 10.3 0.6 2.2 1 1 0 1 1 1 0 RIO1 family HTH_16 PF12645.7 EIM91008.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PHD PF00628.29 EIM91009.1 - 6.4e-07 29.2 4.8 6.4e-07 29.2 4.8 2.2 1 1 1 2 2 2 1 PHD-finger Peptidase_C98 PF15499.6 EIM91009.1 - 0.012 15.1 0.8 0.014 14.9 0.8 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase C1_1 PF00130.22 EIM91009.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 EIM91009.1 - 1.3 9.1 11.7 0.15 12.1 4.0 2.3 1 1 1 2 2 2 0 PHD-finger MOZ_SAS PF01853.18 EIM91010.1 - 4e-67 225.4 0.1 5.7e-67 224.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EIM91010.1 - 1.3e-19 69.6 0.7 1.3e-19 69.6 0.7 1.7 2 0 0 2 2 2 1 MYST family zinc finger domain NCE101 PF11654.8 EIM91011.1 - 0.067 12.9 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Non-classical export protein 1 GFA PF04828.14 EIM91012.1 - 1.4e-12 47.8 0.9 2.6e-12 46.9 0.9 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme D_CNTX PF17492.2 EIM91012.1 - 0.083 13.1 1.3 0.083 13.1 1.3 1.9 2 1 0 2 2 2 0 Delta Ctenitoxins AAL_decarboxy PF03306.13 EIM91012.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase DUF1295 PF06966.12 EIM91013.1 - 5.7e-48 163.5 0.2 7.4e-48 163.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EIM91013.1 - 0.00028 19.8 0.5 0.00061 18.7 0.5 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 EIM91013.1 - 0.00056 20.3 0.1 0.0017 18.7 0.0 2.0 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIM91013.1 - 0.012 16.0 1.7 0.013 15.9 0.0 2.0 2 0 0 2 2 2 0 Phospholipid methyltransferase Steroid_dh PF02544.16 EIM91013.1 - 0.012 15.6 0.5 0.021 14.8 0.5 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase HNH_2 PF13391.6 EIM91014.1 - 9.9e-09 35.2 0.1 1.9e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Phyto_Pns9_10 PF05878.11 EIM91014.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 WD40 PF00400.32 EIM91015.1 - 1.9e-17 63.3 6.6 0.0044 17.8 0.0 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM91015.1 - 3.3e-10 40.1 0.1 7.1e-05 23.0 0.1 4.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIM91015.1 - 0.00017 21.1 0.0 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 EIM91015.1 - 0.0036 17.2 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EIM91015.1 - 0.028 12.8 0.0 0.82 7.9 0.0 2.3 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz FA_hydroxylase PF04116.13 EIM91018.1 - 4.1e-22 79.0 26.9 4.1e-22 78.9 23.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RNase_H PF00075.24 EIM91020.1 - 0.00018 21.7 0.6 0.00023 21.4 0.1 1.4 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.27 EIM91021.1 - 0.0012 18.4 0.1 0.0013 18.3 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EIM91023.1 - 0.002 18.1 1.2 0.002 18.1 1.2 4.1 4 1 0 4 4 4 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIM91023.1 - 0.018 14.9 15.0 0.057 13.3 0.4 3.2 3 0 0 3 3 3 0 Zinc knuckle zf-B_box PF00643.24 EIM91023.1 - 0.022 14.9 13.2 0.16 12.1 6.5 2.6 1 1 1 2 2 2 0 B-box zinc finger zf-CCHC_5 PF14787.6 EIM91023.1 - 0.063 13.0 2.3 0.063 13.0 2.3 2.6 2 1 0 2 2 2 0 GAG-polyprotein viral zinc-finger ArfGap PF01412.18 EIM91023.1 - 2.2 8.4 12.1 15 5.7 11.8 2.0 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf zf-TFIIB PF13453.6 EIM91023.1 - 3.5 7.0 11.9 0.2 11.0 5.2 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger BAG6 PF12057.8 EIM91024.1 - 0.052 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 BCL2-associated athanogene 6 DUF1129 PF06570.11 EIM91024.1 - 0.69 9.4 2.3 0.8 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Asp PF00026.23 EIM91025.1 - 3.9e-64 217.0 5.3 4.9e-64 216.7 5.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM91025.1 - 1.9e-09 38.0 1.5 2.2e-08 34.5 1.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Pkinase PF00069.25 EIM91026.1 - 1.2e-07 31.4 0.0 7.8e-07 28.7 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91026.1 - 0.00056 19.3 0.0 0.00082 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Asp PF00026.23 EIM91027.1 - 1.7e-07 31.0 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease HCMV_UL124 PF17609.2 EIM91027.1 - 0.00071 19.8 0.3 0.00071 19.8 0.3 1.8 2 0 0 2 2 2 1 Family of unknown function TauD PF02668.16 EIM91028.1 - 1.8e-36 126.3 0.0 3.4e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EIM91028.1 - 1.6e-19 70.3 0.2 3.3e-19 69.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EIM91028.1 - 0.0022 17.2 0.0 0.0075 15.4 0.0 1.7 2 0 0 2 2 2 1 CsiD IlvN PF07991.12 EIM91029.1 - 1.3e-46 158.2 0.0 2.2e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EIM91029.1 - 7.1e-40 136.6 0.0 1.1e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EIM91029.1 - 0.099 13.2 0.4 0.24 12.0 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 EIM91030.1 - 6.1e-14 52.1 0.0 9.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91030.1 - 2.9e-09 36.8 0.0 5.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM91030.1 - 0.082 14.0 0.0 0.13 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Aminotran_3 PF00202.21 EIM91031.1 - 2.9e-41 141.5 0.0 3.4e-19 68.8 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EIM91031.1 - 4.3e-17 62.6 0.0 8.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sec61_beta PF03911.16 EIM91032.1 - 8.5e-18 64.1 0.5 1.1e-17 63.8 0.5 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.12 EIM91032.1 - 0.11 12.9 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Sde2_N_Ubi PF13019.6 EIM91033.1 - 6.2e-53 179.0 0.1 8.9e-53 178.5 0.1 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Ribosomal_L12 PF00542.19 EIM91033.1 - 6.5 7.2 8.4 4.3 7.8 1.5 2.7 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain Peptidase_M28 PF04389.17 EIM91034.1 - 2.7e-25 89.3 0.1 4.5e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIM91034.1 - 1.5e-06 28.1 0.0 3.1e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EIM91035.1 - 1e-26 93.9 0.1 1.5e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIM91035.1 - 2.8e-07 30.5 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Aconitase PF00330.20 EIM91036.1 - 3.1e-107 359.4 0.0 3.7e-106 355.9 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIM91036.1 - 1.9e-21 76.8 0.0 6.8e-21 75.0 0.0 1.9 1 1 0 1 1 1 1 Aconitase C-terminal domain UvrD-helicase PF00580.21 EIM91037.1 - 1.5e-66 225.1 0.0 5.9e-66 223.1 0.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EIM91037.1 - 3.6e-53 181.2 0.0 4.4e-52 177.6 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EIM91037.1 - 1.4e-33 116.3 0.0 4.3e-33 114.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EIM91037.1 - 1.3e-13 50.6 0.0 4.2e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EIM91037.1 - 1.8e-08 34.4 0.4 0.0092 15.7 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EIM91037.1 - 5.8e-08 32.7 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EIM91037.1 - 0.00047 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EIM91037.1 - 0.0029 17.2 0.0 0.058 13.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain DDE_Tnp_IS66_C PF13817.6 EIM91037.1 - 0.063 13.5 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 IS66 C-terminal element Spt20 PF12090.8 EIM91037.1 - 0.081 12.5 0.7 0.14 11.7 0.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF99 PF01949.16 EIM91037.1 - 0.15 11.5 0.0 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF99 bZIP_1 PF00170.21 EIM91038.1 - 6.6e-06 26.1 3.1 6.6e-06 26.1 3.1 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EIM91038.1 - 0.0026 17.8 3.8 0.0055 16.8 3.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.13 EIM91038.1 - 0.0096 15.2 0.4 0.012 14.8 0.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ABC_tran_CTD PF16326.5 EIM91038.1 - 0.022 15.0 0.3 0.035 14.4 0.3 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Nnf1 PF03980.14 EIM91038.1 - 0.044 14.2 1.2 0.075 13.4 1.2 1.4 1 0 0 1 1 1 0 Nnf1 CCDC106 PF15794.5 EIM91038.1 - 0.05 13.3 0.6 0.091 12.5 0.3 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 TSC22 PF01166.18 EIM91038.1 - 0.056 13.8 0.3 0.096 13.0 0.3 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family Mto2_bdg PF12808.7 EIM91038.1 - 0.31 11.4 5.1 0.58 10.5 5.1 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HSP20 PF00011.21 EIM91039.1 - 1.3e-09 38.1 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EIM91039.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4588 PF15251.6 EIM91040.1 - 3 7.6 8.2 0.22 11.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) BTB PF00651.31 EIM91041.1 - 1.2e-06 28.8 0.1 3.9e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain tRNA-synt_1g PF09334.11 EIM91042.1 - 4.9e-134 447.0 0.0 6.3e-134 446.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EIM91042.1 - 2.5e-07 30.8 0.1 1.9e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA WHEP-TRS PF00458.20 EIM91042.1 - 3.6e-07 30.2 2.2 9.6e-07 28.9 2.2 1.7 1 0 0 1 1 1 1 WHEP-TRS domain zinc-ribbons_6 PF07191.12 EIM91042.1 - 0.027 14.4 4.6 0.032 14.2 2.9 2.0 2 0 0 2 2 2 0 zinc-ribbons Lant_dehydr_C PF14028.6 EIM91042.1 - 0.083 12.4 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term C1_1 PF00130.22 EIM91042.1 - 0.28 11.1 2.9 1.1 9.2 2.7 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3323 PF11796.8 EIM91042.1 - 1.1 9.1 4.9 2.3 8.0 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DZR PF12773.7 EIM91042.1 - 1.7 8.8 9.9 5.8 7.0 9.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon adh_short_C2 PF13561.6 EIM91043.1 - 3.1e-53 180.7 0.0 4.1e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM91043.1 - 1.8e-40 138.5 0.1 2.5e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM91043.1 - 4e-12 46.4 0.1 6e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 KR domain SH3_1 PF00018.28 EIM91044.1 - 4.6e-14 51.7 0.2 7.1e-14 51.1 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EIM91044.1 - 7.1e-13 48.0 0.0 1.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EIM91044.1 - 1.2e-12 47.5 0.1 1.8e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 EIM91045.1 - 2.7e-34 118.7 34.6 1.3e-26 93.4 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EIM91045.1 - 3.8e-12 45.7 22.7 2.1e-06 26.9 5.7 3.8 2 2 1 3 3 3 3 MFS_1 like family OATP PF03137.20 EIM91045.1 - 0.0016 16.9 5.4 0.0019 16.6 0.6 2.7 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EIM91045.1 - 0.015 14.2 14.0 0.022 13.6 6.3 2.7 2 2 1 3 3 3 0 Sugar (and other) transporter Gti1_Pac2 PF09729.9 EIM91046.1 - 0.044 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family MARVEL PF01284.23 EIM91048.1 - 3e-11 43.5 11.4 4.4e-11 43.0 11.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 EIM91048.1 - 0.075 13.5 2.4 0.8 10.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3309 PF11752.8 EIM91048.1 - 0.3 11.2 2.0 0.38 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF456 PF04306.13 EIM91048.1 - 6.6 7.0 12.7 0.7 10.2 6.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF4140 PF13600.6 EIM91049.1 - 2.9 8.4 6.7 2.8 8.4 0.7 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) NUDIX PF00293.28 EIM91050.1 - 8.4e-12 45.3 0.0 1.9e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Lipase_GDSL_2 PF13472.6 EIM91051.1 - 4.3e-12 46.8 3.9 5.1e-12 46.5 3.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIM91051.1 - 7.9e-06 26.0 2.2 1.5e-05 25.1 2.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase polyprenyl_synt PF00348.17 EIM91052.1 - 1.9e-59 200.8 0.0 6.9e-58 195.7 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EIM91053.1 - 0.0029 17.0 1.6 0.009 15.4 1.2 1.9 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DEAD PF00270.29 EIM91054.1 - 1.9e-52 177.6 0.0 1.6e-51 174.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM91054.1 - 4.5e-32 110.7 0.0 2e-30 105.4 0.0 2.5 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM91054.1 - 1.9e-07 31.2 0.0 5.2e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EIM91054.1 - 0.12 11.1 0.0 0.61 8.8 0.0 2.0 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GRP PF07172.11 EIM91054.1 - 0.16 12.7 33.5 0.39 11.4 33.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family Glyco_hydro_79C PF16862.5 EIM91055.1 - 1.1e-18 68.0 0.8 3.4e-18 66.4 0.1 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain P34-Arc PF04045.14 EIM91056.1 - 1.1e-110 369.0 0.2 1.3e-110 368.8 0.2 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc RRM_1 PF00076.22 EIM91057.1 - 1.4e-13 50.4 0.1 2.5e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBOAT_2 PF13813.6 EIM91058.1 - 1.4e-16 60.5 1.6 9e-16 57.9 0.2 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family p47_phox_C PF08944.11 EIM91058.1 - 0.16 11.4 0.9 0.34 10.4 0.9 1.5 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Ras PF00071.22 EIM91059.1 - 3e-49 166.7 0.1 3.4e-49 166.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM91059.1 - 2.2e-18 66.6 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EIM91059.1 - 3.7e-08 33.5 0.0 0.0002 21.3 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 EIM91059.1 - 5.2e-08 32.5 0.0 6.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIM91059.1 - 4.9e-05 23.0 0.1 0.00018 21.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIM91059.1 - 0.00019 21.5 0.1 0.00035 20.6 0.1 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ImcF-related_N PF14331.6 EIM91059.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain FeoB_N PF02421.18 EIM91059.1 - 0.022 14.3 0.1 0.058 12.9 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 EIM91059.1 - 0.063 12.6 0.1 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 EIM91059.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Pro_isomerase PF00160.21 EIM91060.1 - 2.5e-41 141.6 0.0 3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.22 EIM91061.1 - 5.5e-67 226.5 0.0 2e-66 224.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.18 EIM91063.1 - 2.3e-08 34.0 12.8 4.4e-08 33.1 12.8 1.5 1 0 0 1 1 1 1 MYND finger Tmemb_18A PF09771.9 EIM91063.1 - 0.058 13.8 0.0 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 188 Glyco_hydro_79C PF16862.5 EIM91064.1 - 3.8e-20 72.7 0.5 1.1e-19 71.3 0.5 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain NAPRTase PF04095.16 EIM91066.1 - 4.6e-60 203.2 0.0 5.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EIM91066.1 - 1.3e-36 125.7 0.1 1.9e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Methyltransf_4 PF02390.17 EIM91067.1 - 7.1e-50 168.8 0.0 1.4e-48 164.7 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EIM91067.1 - 0.0019 18.9 0.0 0.064 14.0 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91067.1 - 0.031 15.0 0.0 0.086 13.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EIM91067.1 - 0.091 13.4 0.0 15 6.4 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Thaumatin PF00314.17 EIM91068.1 - 7.3e-16 58.5 2.6 7.3e-16 58.5 2.6 2.0 1 1 1 2 2 2 2 Thaumatin family DUF4307 PF14155.6 EIM91068.1 - 0.04 13.7 1.2 0.069 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DnaJ PF00226.31 EIM91069.1 - 3.1e-15 56.0 0.5 8.1e-15 54.7 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain HAND PF09110.11 EIM91069.1 - 6.3 7.6 15.3 9.4 7.0 8.7 2.6 2 1 0 2 2 2 0 HAND RMI1_N PF08585.12 EIM91070.1 - 4.1e-31 108.4 0.0 5.1e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein FluMu_N PF17891.1 EIM91070.1 - 0.22 11.3 0.8 0.54 10.1 0.1 1.9 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain Carn_acyltransf PF00755.20 EIM91071.1 - 1.3e-157 526.0 0.0 3.9e-157 524.4 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_12 PF13087.6 EIM91072.1 - 4.6e-26 91.7 0.0 6.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM91072.1 - 2.9e-10 40.4 0.2 1.5e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM91072.1 - 0.00045 20.0 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM91072.1 - 0.0016 18.8 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EIM91074.1 - 5.8e-26 91.3 0.0 8.4e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIM91074.1 - 1.4e-09 38.2 0.1 1.3e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EIM91074.1 - 4.6e-05 23.3 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EIM91074.1 - 0.00078 19.2 0.3 0.0015 18.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EIM91074.1 - 0.025 14.9 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pam16 PF03656.13 EIM91075.1 - 0.00039 20.4 0.0 0.00047 20.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EIM91075.1 - 0.0038 17.3 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain NmrA PF05368.13 EIM91076.1 - 2.5e-33 115.6 0.0 3.7e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM91076.1 - 3.2e-05 23.9 0.1 7.6e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Abhydrolase_3 PF07859.13 EIM91077.1 - 1.6e-34 119.7 0.0 2.1e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF5349 PF17298.2 EIM91078.1 - 0.65 9.7 13.4 1.1 9.0 13.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF515 PF04415.12 EIM91078.1 - 9.8 4.4 13.8 10 4.4 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase_fungal PF17667.1 EIM91079.1 - 2.3e-10 39.8 0.0 3.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Roughex PF06020.11 EIM91079.1 - 2.1 7.3 5.5 4.1 6.4 5.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF1754 PF08555.10 EIM91079.1 - 6.3 7.7 12.0 7.1 7.5 5.8 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Pcc1 PF09341.10 EIM91080.1 - 2.1e-24 85.5 0.4 2.3e-24 85.3 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Peptidase_M24 PF00557.24 EIM91081.1 - 2.1e-19 70.1 0.1 2.8e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_25 PF13649.6 EIM91082.1 - 8.1e-16 58.5 0.0 1.5e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM91082.1 - 8.4e-14 52.0 0.0 1.9e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM91082.1 - 3.6e-09 36.7 0.0 6.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM91082.1 - 3.6e-08 33.0 0.0 5.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EIM91082.1 - 8e-07 29.0 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91082.1 - 1.9e-06 28.6 0.0 5.6e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EIM91082.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EIM91082.1 - 0.00057 19.5 0.0 0.0015 18.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EIM91082.1 - 0.0012 18.4 0.0 0.0035 16.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 EIM91082.1 - 0.0043 16.4 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 EIM91082.1 - 0.02 14.6 0.0 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase PCMT PF01135.19 EIM91082.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EIM91082.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EIM91082.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EIM91082.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NDUF_B8 PF05821.11 EIM91083.1 - 7.6e-05 22.6 0.0 9.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) XPG_N PF00752.17 EIM91084.1 - 2.8e-30 104.8 0.0 6.5e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EIM91084.1 - 1.3e-26 92.8 0.0 4e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EIM91084.1 - 0.00092 18.8 0.0 0.0032 17.0 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 EIM91084.1 - 0.069 13.8 0.5 0.5 11.0 0.0 2.6 4 0 0 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold PH PF00169.29 EIM91088.1 - 0.00014 22.3 0.0 0.0013 19.2 0.0 2.4 2 0 0 2 2 2 1 PH domain PBP1_TM PF14812.6 EIM91088.1 - 1.5 9.3 19.6 0.3 11.5 5.5 3.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase_fungal PF17667.1 EIM91089.1 - 3.4e-54 184.2 0.0 1.7e-41 142.3 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM91089.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIM91089.1 - 0.00021 21.3 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM91089.1 - 0.003 17.2 0.4 0.0078 15.8 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EIM91089.1 - 0.051 12.5 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CtaG_Cox11 PF04442.14 EIM91090.1 - 8.1e-60 201.2 0.1 9.8e-60 201.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 ING PF12998.7 EIM91091.1 - 1.2e-12 48.2 0.7 2.3e-12 47.4 0.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EIM91091.1 - 3e-05 23.8 7.8 4.7e-05 23.2 7.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EIM91091.1 - 0.0017 18.6 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain CCDC24 PF15669.5 EIM91091.1 - 0.0044 16.9 0.4 0.0085 16.0 0.4 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family FlgN PF05130.12 EIM91091.1 - 0.016 15.7 2.1 2.1 8.8 0.4 2.3 2 0 0 2 2 2 0 FlgN protein Lipase_GDSL_2 PF13472.6 EIM91092.1 - 6.1e-11 43.0 2.5 7.8e-11 42.7 2.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIM91092.1 - 0.0025 17.8 1.8 0.0049 16.9 1.8 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Endonuclease_7 PF02945.15 EIM91092.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.5 1 1 0 1 1 1 0 Recombination endonuclease VII Phosphonate-bd PF12974.7 EIM91093.1 - 1.1e-06 28.5 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EIM91093.1 - 6.7e-05 22.9 0.0 9.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 EIM91093.1 - 0.00018 21.0 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family LysR_substrate PF03466.20 EIM91093.1 - 0.21 11.0 0.0 0.69 9.2 0.0 1.9 1 1 0 1 1 1 0 LysR substrate binding domain DUF202 PF02656.15 EIM91095.1 - 0.052 14.0 0.4 0.069 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Adhesin_P1_N PF18652.1 EIM91095.1 - 0.16 12.0 0.8 0.21 11.6 0.8 1.1 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain TPR_2 PF07719.17 EIM91096.1 - 9.8e-08 31.6 4.0 0.12 12.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM91096.1 - 9.3e-07 29.3 3.1 4.5e-06 27.1 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EIM91096.1 - 1.4e-05 25.1 0.1 3.6e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91096.1 - 1.5e-05 24.6 6.6 0.0094 15.7 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM91096.1 - 2.6e-05 24.7 0.4 0.0028 18.3 0.5 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIM91096.1 - 0.0012 18.8 0.0 4.5 7.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM91096.1 - 0.0024 18.1 1.4 0.012 15.8 0.2 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EIM91096.1 - 0.0042 17.4 0.3 0.042 14.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat SPO22 PF08631.10 EIM91096.1 - 0.0043 16.6 1.2 0.095 12.2 0.5 2.2 2 1 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_20 PF14561.6 EIM91096.1 - 0.0051 17.1 3.6 0.0092 16.3 0.4 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF4919 PF16266.5 EIM91096.1 - 0.021 14.8 0.2 0.04 13.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4919) Fis1_TPR_C PF14853.6 EIM91096.1 - 0.097 12.8 0.2 1.7 8.8 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 EIM91096.1 - 0.12 12.7 1.1 0.7 10.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM91096.1 - 0.58 10.9 4.3 8 7.3 0.1 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat IQCJ-SCHIP1 PF15157.6 EIM91097.1 - 0.033 14.0 0.7 0.033 14.0 0.7 1.8 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Fumble PF03630.14 EIM91102.1 - 0.023 13.9 0.0 5.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Fumble Acyl-CoA_dh_1 PF00441.24 EIM91103.1 - 1.8e-30 106.1 1.0 2.7e-30 105.6 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIM91103.1 - 3.4e-18 65.6 0.4 6.6e-18 64.7 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EIM91103.1 - 4.9e-16 58.6 0.0 1.2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EIM91103.1 - 1.9e-14 54.3 0.1 9.7e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EIM91103.1 - 2.5e-07 31.1 0.1 4.8e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase_fungal PF17667.1 EIM91104.1 - 9.1e-57 192.7 0.0 7.2e-44 150.2 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EIM91104.1 - 2.8e-05 23.6 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIM91104.1 - 0.00056 19.6 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM91104.1 - 0.016 15.1 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM91104.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain F-box PF00646.33 EIM91105.1 - 6.2e-07 29.1 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM91105.1 - 0.0057 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like Actin PF00022.19 EIM91106.1 - 1.1e-38 132.9 0.0 4.4e-32 111.2 0.0 3.3 3 1 0 3 3 3 3 Actin Arrestin_N PF00339.29 EIM91107.1 - 1.8e-07 31.4 0.4 5.1e-05 23.4 0.4 2.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Pyrophosphatase PF00719.19 EIM91108.1 - 5.5e-40 136.8 0.0 6.8e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Methyltransf_16 PF10294.9 EIM91109.1 - 1.8e-19 70.2 0.0 2e-18 66.7 0.0 2.3 1 1 0 1 1 1 1 Lysine methyltransferase Cellulase PF00150.18 EIM91110.1 - 3.6e-19 69.3 0.0 5.1e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Na_H_Exchanger PF00999.21 EIM91111.1 - 1.5e-32 112.8 40.7 7.6e-32 110.5 40.7 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family LapA_dom PF06305.11 EIM91111.1 - 0.12 12.2 3.9 3.4 7.6 0.1 3.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain GMC_oxred_C PF05199.13 EIM91112.1 - 0.0001 22.9 0.1 0.00018 22.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase ABC_membrane PF00664.23 EIM91113.1 - 7.4e-61 206.2 33.3 5.2e-33 114.9 14.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM91113.1 - 1.1e-51 174.9 0.1 7.5e-27 94.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EIM91113.1 - 2.7e-10 40.0 1.0 0.0066 15.9 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIM91113.1 - 4.9e-06 27.2 1.6 0.014 15.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EIM91113.1 - 2.2e-05 24.5 1.3 0.081 13.0 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EIM91113.1 - 7.4e-05 22.4 1.8 0.14 11.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EIM91113.1 - 7.5e-05 22.7 2.1 0.072 12.9 0.1 3.9 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EIM91113.1 - 0.00021 21.7 0.0 0.059 13.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EIM91113.1 - 0.00075 19.4 1.0 0.13 12.1 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase ATP-synt_ab PF00006.25 EIM91113.1 - 0.0032 17.2 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EIM91113.1 - 0.0054 16.3 0.7 0.96 8.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EIM91113.1 - 0.0063 15.5 1.7 1.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EIM91113.1 - 0.012 15.2 1.3 0.044 13.4 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EIM91113.1 - 0.017 15.2 2.1 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 EIM91113.1 - 0.02 14.7 1.6 1.8 8.3 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 EIM91113.1 - 0.024 14.2 0.2 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EIM91113.1 - 0.028 14.7 2.9 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EIM91113.1 - 0.031 14.0 0.1 2.8 7.6 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EIM91113.1 - 0.032 14.5 4.4 0.47 10.7 0.1 3.4 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 EIM91113.1 - 0.045 13.5 4.0 4.3 7.0 0.2 2.8 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 EIM91113.1 - 0.049 12.9 1.3 1.1 8.5 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin CtIP_N PF10482.9 EIM91113.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain MobB PF03205.14 EIM91113.1 - 0.078 12.9 0.6 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 EIM91113.1 - 0.088 13.2 0.6 2.5 8.5 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EIM91113.1 - 0.094 12.8 6.2 0.49 10.5 0.8 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain RecA PF00154.21 EIM91113.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_13 PF13166.6 EIM91113.1 - 0.17 10.5 0.0 0.31 9.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EIM91113.1 - 0.22 12.1 0.4 23 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EIM91113.1 - 0.29 10.9 2.5 0.65 9.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EIM91113.1 - 0.32 10.9 1.2 0.8 9.6 0.1 2.1 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EIM91113.1 - 0.66 9.7 3.0 34 4.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein PSDC PF12588.8 EIM91114.1 - 1.8e-47 160.8 0.0 3.1e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EIM91114.1 - 1.8e-41 141.9 0.0 2.4e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 EIM91114.1 - 0.045 13.7 0.1 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EIM91114.1 - 0.054 13.3 0.2 0.67 9.8 0.1 2.2 2 0 0 2 2 2 0 Biotin-requiring enzyme Peptidase_M23 PF01551.22 EIM91114.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M23 DUF2852 PF11014.8 EIM91115.1 - 0.024 14.8 0.1 0.044 13.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) FAM176 PF14851.6 EIM91115.1 - 0.027 14.2 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 EIM91115.1 - 0.19 12.7 0.0 1.1 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Actin PF00022.19 EIM91116.1 - 2.2e-85 286.7 0.0 8.2e-84 281.6 0.0 2.0 1 1 0 1 1 1 1 Actin TPR_2 PF07719.17 EIM91117.1 - 8.6e-30 100.4 2.1 7.3e-05 22.6 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91117.1 - 1.7e-25 87.8 3.4 2.5e-07 30.2 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EIM91117.1 - 9.4e-23 80.3 3.3 3.3e-10 40.0 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EIM91117.1 - 8e-19 67.7 13.8 1.2e-09 38.3 0.0 7.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIM91117.1 - 8.4e-18 63.0 0.3 0.00011 22.1 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM91117.1 - 2.8e-12 46.9 1.0 0.016 15.7 0.0 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIM91117.1 - 2.6e-11 43.0 0.7 0.0006 19.4 0.0 5.9 6 1 1 7 7 7 3 TPR repeat TPR_7 PF13176.6 EIM91117.1 - 6.9e-08 32.0 5.4 0.35 11.0 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM91117.1 - 3.8e-07 30.6 10.9 0.39 11.4 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EIM91117.1 - 2e-06 28.0 10.0 0.018 15.6 0.0 7.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIM91117.1 - 4.6e-06 26.3 13.6 0.04 13.8 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM91117.1 - 1.1e-05 25.8 12.2 3.5 8.7 0.0 8.2 6 2 4 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIM91117.1 - 9.3e-05 22.6 3.6 0.66 10.5 0.0 6.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 EIM91117.1 - 0.00084 19.7 4.3 1.5 9.7 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM91117.1 - 0.0028 17.1 5.0 0.0083 15.5 0.3 3.2 2 1 2 4 4 4 1 MalT-like TPR region SNAP PF14938.6 EIM91117.1 - 0.022 14.2 0.1 0.27 10.6 0.2 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 EIM91117.1 - 0.023 14.7 0.6 20 5.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 EIM91117.1 - 0.14 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3494 PF11999.8 EIM91118.1 - 8.5e-56 188.9 15.1 1e-55 188.6 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) SH3_12 PF18129.1 EIM91118.1 - 0.06 13.5 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Xrn1 SH3-like domain RD3 PF14473.6 EIM91119.1 - 0.054 13.3 0.4 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 RD3 protein DUF4215 PF13948.6 EIM91119.1 - 0.76 10.3 0.0 0.76 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) RRM_1 PF00076.22 EIM91120.1 - 2.3e-14 53.0 0.0 4.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIM91120.1 - 0.11 12.6 0.2 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif RPA43_OB PF17875.1 EIM91123.1 - 0.049 14.3 0.2 0.13 12.8 0.2 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Complex1_LYR PF05347.15 EIM91124.1 - 1.5e-12 47.3 0.3 1.5e-12 47.3 0.3 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EIM91124.1 - 4.2e-05 24.2 1.6 7.6e-05 23.4 1.7 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Sugar_tr PF00083.24 EIM91125.1 - 4.1e-50 171.0 24.9 4.8e-50 170.7 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM91125.1 - 7.1e-19 67.9 29.0 7.1e-19 67.9 29.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1206 PF06724.11 EIM91125.1 - 0.54 10.4 16.4 1 9.5 0.9 4.8 3 2 1 4 4 4 0 Domain of Unknown Function (DUF1206) Acetyltransf_9 PF13527.7 EIM91126.1 - 0.00067 19.7 0.0 0.0035 17.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM91126.1 - 0.0036 17.7 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM91126.1 - 0.049 13.6 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM91126.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3494 PF11999.8 EIM91127.1 - 1.1e-58 198.3 15.3 1.3e-58 198.0 15.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF4800 PF16057.5 EIM91129.1 - 0.068 12.4 0.8 0.13 11.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) zf-C2H2_aberr PF17017.5 EIM91129.1 - 0.099 12.8 0.7 3.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger Presenilin PF01080.17 EIM91129.1 - 2.7 6.7 3.6 4.1 6.1 3.6 1.2 1 0 0 1 1 1 0 Presenilin Methyltransf_2 PF00891.18 EIM91130.1 - 1e-14 54.3 0.0 3.5e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 EIM91130.1 - 0.0007 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EIM91130.1 - 0.069 13.9 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91130.1 - 0.089 13.5 0.0 0.64 10.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EIM91130.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.11 EIM91130.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 EIM91130.1 - 0.14 11.9 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 EIM91130.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RNase_H PF00075.24 EIM91131.1 - 7.3e-13 48.9 0.0 2.5e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 EIM91131.1 - 1.7e-06 28.7 2.6 2.8e-06 28.0 0.9 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase XPA_C PF05181.12 EIM91132.1 - 3.6e-07 30.0 0.1 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 2 XPA protein C-terminus XPA_C PF05181.12 EIM91134.1 - 0.0069 16.3 0.0 0.094 12.7 0.0 2.1 2 0 0 2 2 2 1 XPA protein C-terminus XPA_C PF05181.12 EIM91135.1 - 0.00015 21.7 2.2 0.31 11.1 0.0 2.7 3 0 0 3 3 3 2 XPA protein C-terminus Ank_5 PF13857.6 EIM91136.1 - 0.0088 16.4 0.4 4.8 7.6 0.1 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM91136.1 - 0.033 14.7 0.9 1 10.2 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 EIM91136.1 - 0.057 14.0 0.0 1.1 9.9 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM91136.1 - 0.14 12.8 0.5 2.4 8.8 0.1 3.1 2 1 2 4 4 4 0 Ankyrin repeats (many copies) eIF-1a PF01176.19 EIM91137.1 - 4.1e-23 81.0 0.0 6e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ADH_zinc_N PF00107.26 EIM91140.1 - 4.2e-19 68.8 0.1 7.8e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91140.1 - 3.2e-09 36.6 0.0 8.7e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM91140.1 - 0.0019 19.2 0.0 0.003 18.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PKD_channel PF08016.12 EIM91141.1 - 6.8e-05 21.7 3.2 6.8e-05 21.7 3.2 2.5 3 0 0 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 EIM91141.1 - 0.26 10.5 24.1 1.2 8.3 24.1 2.0 1 1 0 1 1 1 0 Ion transport protein Cytochrom_B_C PF00032.17 EIM91141.1 - 3 8.2 7.7 4 7.8 0.4 2.8 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Pkinase PF00069.25 EIM91142.1 - 2.4e-61 207.4 0.0 3.3e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91142.1 - 3.8e-30 105.0 0.0 5.3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM91142.1 - 3.5e-08 33.1 0.0 5.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIM91142.1 - 3.3e-05 22.8 0.4 6.1e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EIM91142.1 - 0.0041 16.5 0.5 0.0074 15.7 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2851 PF11013.8 EIM91142.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) APH PF01636.23 EIM91143.1 - 0.00027 20.9 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EMC3_TMCO1 PF01956.16 EIM91144.1 - 0.087 12.6 1.0 0.14 11.9 1.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like NPR3 PF03666.13 EIM91146.1 - 3.8e-98 329.3 0.0 2e-74 251.1 0.0 2.2 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 DUF3320 PF11784.8 EIM91146.1 - 0.22 11.5 1.2 0.5 10.4 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Methyltransf_25 PF13649.6 EIM91147.1 - 0.00097 19.8 0.0 0.0076 16.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Aldo_ket_red PF00248.21 EIM91148.1 - 7.1e-76 255.2 0.0 8.1e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SART-1 PF03343.13 EIM91150.1 - 3.3e-166 554.6 56.5 3.3e-166 554.6 56.5 1.8 2 0 0 2 2 2 2 SART-1 family Macro PF01661.21 EIM91151.1 - 4e-44 149.5 0.1 5.4e-44 149.0 0.1 1.2 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.24 EIM91152.1 - 1.3e-100 337.4 18.4 1.6e-100 337.1 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM91152.1 - 9.8e-23 80.6 30.5 9.8e-23 80.6 30.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 EIM91153.1 - 2.8e-48 164.5 8.6 4.2e-48 163.9 8.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM91153.1 - 3.9e-46 157.0 10.1 7.8e-46 156.0 10.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM91153.1 - 1.3e-08 35.0 4.8 1.6e-08 34.7 4.2 1.5 1 1 0 1 1 1 1 KR domain Acyl-CoA_dh_1 PF00441.24 EIM91154.1 - 8e-31 107.3 1.8 1.3e-30 106.6 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIM91154.1 - 2.2e-18 66.3 0.5 4.1e-18 65.4 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EIM91154.1 - 4.8e-16 59.4 0.0 1.2e-15 58.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EIM91154.1 - 5e-15 55.4 0.0 1.2e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EIM91154.1 - 6.7e-06 26.4 0.2 1.3e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COLFI PF01410.18 EIM91154.1 - 0.15 11.3 0.4 0.34 10.2 0.4 1.5 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain PHD PF00628.29 EIM91155.1 - 1.6e-08 34.3 10.1 2.8e-08 33.5 10.1 1.4 1 0 0 1 1 1 1 PHD-finger Mem_trans PF03547.18 EIM91155.1 - 0.067 11.6 0.3 0.12 10.8 0.3 1.4 1 0 0 1 1 1 0 Membrane transport protein BTB PF00651.31 EIM91157.1 - 9e-06 25.9 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain RAB3GAP2_C PF14656.6 EIM91157.1 - 0.052 11.8 0.1 0.068 11.4 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus SinI PF08671.10 EIM91157.1 - 0.087 12.6 0.3 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 Anti-repressor SinI Hydrolase_4 PF12146.8 EIM91159.1 - 0.0011 18.3 0.0 0.34 10.1 0.0 3.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 PEP_mutase PF13714.6 EIM91160.1 - 1.4e-40 139.3 0.6 1.6e-40 139.1 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EIM91160.1 - 4.4e-19 68.4 0.4 6e-19 67.9 0.4 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Toprim_3 PF13362.6 EIM91160.1 - 0.076 13.4 2.6 3.2 8.2 0.4 2.8 2 1 0 2 2 2 0 Toprim domain LysM PF01476.20 EIM91161.1 - 1e-05 25.5 0.0 2.8e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 LysM domain Metallophos PF00149.28 EIM91162.1 - 2.3e-06 28.3 1.1 6.8e-06 26.7 0.5 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM91162.1 - 0.0017 18.6 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Bac_rhamnosid_C PF17390.2 EIM91163.1 - 2e-14 53.2 0.5 5.5e-14 51.7 0.5 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 EIM91163.1 - 1.1e-13 51.2 0.1 2.2e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 EIM91163.1 - 4e-05 22.5 0.6 0.00012 21.0 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Trehalase PF01204.18 EIM91163.1 - 0.042 12.7 0.2 0.062 12.1 0.2 1.2 1 0 0 1 1 1 0 Trehalase HUN PF08729.10 EIM91163.1 - 0.12 12.4 0.1 17 5.5 0.0 2.6 2 0 0 2 2 2 0 HPC2 and ubinuclein domain CTU2 PF10288.9 EIM91164.1 - 2.4e-18 66.4 0.2 8.4e-18 64.7 0.2 2.0 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Cytochrome_C7 PF14522.6 EIM91164.1 - 0.076 13.0 2.4 0.54 10.3 0.4 2.5 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c zf-C3HC4_3 PF13920.6 EIM91164.1 - 0.53 10.2 9.3 0.2 11.5 0.6 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Paired_CXXCH_1 PF09699.10 EIM91164.1 - 0.56 10.0 2.2 1 9.2 0.0 2.6 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) DZR PF12773.7 EIM91164.1 - 4.2 7.5 11.5 13 5.9 0.6 3.1 2 2 0 2 2 2 0 Double zinc ribbon RVT_1 PF00078.27 EIM91165.1 - 0.00038 20.1 0.0 0.00073 19.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 EIM91166.1 - 2e-12 47.5 0.0 2.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 EIM91167.1 - 0.00011 22.8 0.8 0.00011 22.8 0.8 2.5 2 2 2 4 4 4 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 EIM91167.1 - 0.00033 20.9 0.3 0.0009 19.4 0.1 1.9 2 0 0 2 2 2 1 RNase H YAcAr PF10686.9 EIM91167.1 - 0.028 14.4 0.3 6.6 6.8 0.1 3.1 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family rve PF00665.26 EIM91169.1 - 5.9e-16 58.7 0.1 1.3e-15 57.6 0.0 1.6 1 1 1 2 2 2 1 Integrase core domain rve_3 PF13683.6 EIM91169.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 Integrase core domain DDE_3 PF13358.6 EIM91170.1 - 0.0065 16.2 0.0 0.02 14.6 0.0 1.8 3 0 0 3 3 3 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIM91171.1 - 0.0001 22.1 0.1 0.0034 17.1 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Arm_3 PF16186.5 EIM91171.1 - 0.1 12.2 0.1 0.1 12.2 0.1 1.9 2 0 0 2 2 2 0 Atypical Arm repeat Bromo_TP PF07524.13 EIM91171.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Peptidase_M24_C PF16188.5 EIM91172.1 - 0.13 12.4 0.1 7.1 6.8 0.0 2.7 2 1 0 2 2 2 0 C-terminal region of peptidase_M24 SH3_13 PF18335.1 EIM91173.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain F-box-like PF12937.7 EIM91175.1 - 2.9e-10 39.9 1.6 2.9e-10 39.9 1.6 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM91175.1 - 7.9e-08 32.0 2.2 1e-07 31.6 0.3 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM91176.1 - 6.8e-14 51.5 0.3 1.4e-13 50.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91176.1 - 3.7e-05 23.5 0.0 0.00014 21.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EIM91176.1 - 0.012 15.3 0.1 1.6 8.6 0.0 3.2 2 1 0 2 2 2 0 Leucine rich repeat F-box_4 PF15966.5 EIM91176.1 - 0.11 12.4 0.2 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 F-box YchF-GTPase_C PF06071.13 EIM91178.1 - 5.4e-35 119.4 0.1 1.9e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EIM91178.1 - 1.5e-18 67.0 0.0 3.9e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM91178.1 - 8.9e-06 25.3 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EIM91178.1 - 0.075 12.0 0.2 0.46 9.4 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EIM91178.1 - 0.2 11.7 0.9 0.57 10.2 0.2 2.1 2 1 1 3 3 3 0 Dynamin family AAA-ATPase_like PF09820.9 EIM91179.1 - 0.0017 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase MBOAT_2 PF13813.6 EIM91180.1 - 2.8e-10 40.3 1.6 2.8e-09 37.1 1.6 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family UPF0016 PF01169.19 EIM91183.1 - 2.8e-44 149.3 18.7 2e-23 82.5 8.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EIM91183.1 - 0.0019 18.0 5.9 0.0069 16.1 0.2 2.3 2 0 0 2 2 2 2 Putative manganese efflux pump LysE PF01810.18 EIM91183.1 - 0.0039 16.7 7.9 0.26 10.7 0.1 2.5 2 0 0 2 2 2 2 LysE type translocator TerC PF03741.16 EIM91183.1 - 2.4 7.8 7.8 0.49 10.1 0.4 2.7 2 1 1 3 3 3 0 Integral membrane protein TerC family PITH PF06201.13 EIM91184.1 - 1.6e-39 135.5 0.0 2.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Op_neuropeptide PF08035.11 EIM91184.1 - 0.00028 20.7 0.1 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 Opioids neuropeptide UBX PF00789.20 EIM91185.1 - 1.3e-11 44.5 0.2 2.3e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 UBX domain Peptidase_C2 PF00648.21 EIM91186.1 - 7.6e-68 228.7 2.1 7.9e-67 225.4 2.1 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease TSP_3 PF02412.18 EIM91186.1 - 0.22 11.2 1.9 0.5 10.1 1.9 1.5 1 0 0 1 1 1 0 Thrombospondin type 3 repeat SARAF PF06682.12 EIM91188.1 - 1.3e-72 245.3 1.0 1.5e-72 245.1 1.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Sugar_tr PF00083.24 EIM91189.1 - 1.9e-119 399.5 25.6 2.5e-119 399.1 25.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM91189.1 - 1.5e-28 99.8 54.1 2.4e-22 79.3 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Presenilin PF01080.17 EIM91190.1 - 8.9 5.0 5.1 8 5.1 5.1 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EIM91190.1 - 9 4.9 9.2 8.2 5.0 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 EIM91192.1 - 2.6e-14 52.9 15.3 2.6e-14 52.9 15.3 2.9 2 1 1 3 3 3 1 Major Facilitator Superfamily F-box-like PF12937.7 EIM91194.1 - 4.8e-06 26.4 0.1 1.2e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like Uroplakin_II PF07353.12 EIM91194.1 - 0.027 14.0 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Uroplakin II LRR_4 PF12799.7 EIM91194.1 - 0.15 12.5 1.1 4.6 7.8 0.0 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) ThiF PF00899.21 EIM91195.1 - 2.3e-65 220.4 0.0 3.3e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EIM91195.1 - 3e-10 40.6 0.0 1.4e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain ApbA PF02558.16 EIM91195.1 - 0.0028 17.3 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EIM91195.1 - 0.0028 17.7 0.2 0.018 15.1 0.1 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EIM91195.1 - 0.065 13.5 0.4 0.26 11.6 0.4 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EIM91195.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EIM91195.1 - 0.086 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EIM91195.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EIM91195.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ANAPC10 PF03256.16 EIM91196.1 - 3.7e-48 163.6 0.0 4.9e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EIM91196.1 - 0.004 17.3 0.0 0.012 15.7 0.0 1.8 1 1 1 2 2 2 1 F5/8 type C domain Polysacc_lyase PF14099.6 EIM91196.1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase ATP-synt_G PF04718.15 EIM91197.1 - 0.083 13.7 0.4 0.58 11.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Goodbye PF17109.5 EIM91197.1 - 0.14 12.6 1.7 0.34 11.4 0.1 2.4 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain LMBR1 PF04791.16 EIM91197.1 - 0.23 10.3 0.8 0.39 9.6 0.8 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4854 PF16146.5 EIM91197.1 - 0.24 11.7 2.7 1.7 9.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) Apolipoprotein PF01442.18 EIM91197.1 - 0.44 10.4 6.1 2.2 8.1 1.7 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain MCPsignal PF00015.21 EIM91197.1 - 0.56 10.0 5.3 1.6 8.5 1.0 3.0 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain COG5 PF10392.9 EIM91197.1 - 0.93 9.7 5.1 1.4 9.1 0.5 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Syntaxin-6_N PF09177.11 EIM91197.1 - 1.2 9.7 7.0 11 6.6 3.4 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Med25 PF11232.8 EIM91199.1 - 0.0027 17.7 1.8 0.0045 17.0 0.1 2.2 2 0 0 2 2 2 1 Mediator complex subunit 25 PTOV activation and synapsin 2 PEX11 PF05648.14 EIM91199.1 - 0.64 9.5 2.0 0.54 9.7 0.1 1.8 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) V_ATPase_I PF01496.19 EIM91199.1 - 2.2 6.1 5.4 4.8 5.0 5.4 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C2 PF00648.21 EIM91200.1 - 5.4e-65 219.3 1.2 3.3e-64 216.8 1.2 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease DUF3852 PF12963.7 EIM91201.1 - 7 7.0 10.5 0.86 10.0 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3852) ADH_zinc_N PF00107.26 EIM91203.1 - 6.6e-14 52.0 0.1 1.2e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91203.1 - 2.2e-09 37.2 0.0 1.1e-08 34.9 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EIM91203.1 - 4.6e-05 23.0 0.4 9.7e-05 21.9 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EIM91203.1 - 0.00099 18.7 0.2 0.0015 18.1 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family AlaDh_PNT_C PF01262.21 EIM91203.1 - 0.0012 18.2 1.9 0.0013 18.0 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Fibrillarin PF01269.17 EIM91203.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin ADH_zinc_N_2 PF13602.6 EIM91203.1 - 0.091 13.8 0.0 0.23 12.5 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RabGAP-TBC PF00566.18 EIM91204.1 - 2e-49 168.2 0.0 3.2e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_76 PF03663.14 EIM91205.1 - 7.1e-30 104.7 11.4 1.3e-29 103.9 11.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.14 EIM91206.1 - 6.4e-27 95.0 19.2 8.2e-27 94.7 19.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 LRR_4 PF12799.7 EIM91207.1 - 0.0061 16.9 0.8 1 9.9 0.0 3.0 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM91207.1 - 0.02 14.7 0.4 0.21 11.3 0.1 2.5 1 1 1 2 2 2 0 Leucine rich repeat Sigma70_ner PF04546.13 EIM91207.1 - 3.6 7.4 9.4 5.5 6.8 9.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DDE_Tnp_4 PF13359.6 EIM91208.1 - 3.7e-22 78.7 0.0 4.7e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.6 EIM91209.1 - 0.12 12.7 0.6 0.2 12.1 0.1 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MINDY_DUB PF04424.13 EIM91211.1 - 2e-25 89.1 0.0 5.4e-25 87.7 0.0 1.8 2 0 0 2 2 2 1 MINDY deubiquitinase F-box-like PF12937.7 EIM91212.1 - 2e-09 37.2 0.4 5.2e-09 35.9 0.4 1.8 1 0 0 1 1 1 1 F-box-like FMN_dh PF01070.18 EIM91213.1 - 8.1e-105 350.7 0.2 1.2e-104 350.1 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EIM91213.1 - 4e-15 55.7 0.0 8.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 EIM91213.1 - 3e-06 26.5 1.4 1.5e-05 24.2 0.5 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EIM91213.1 - 6.3e-06 25.6 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EIM91213.1 - 0.00037 20.0 0.8 0.0015 17.9 1.2 1.8 1 1 1 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 EIM91213.1 - 0.0039 16.5 0.0 0.25 10.6 0.1 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Peptidase_C32 PF05411.12 EIM91213.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Equine arteritis virus putative proteinase DHO_dh PF01180.21 EIM91213.1 - 0.11 11.7 0.1 0.31 10.2 0.1 1.6 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Abhydrolase_3 PF07859.13 EIM91214.1 - 1.6e-12 47.7 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM91214.1 - 5.9e-10 38.6 2.9 2.5e-09 36.6 2.9 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EIM91214.1 - 8.1e-07 29.9 0.2 1.1e-06 29.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EIM91214.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 EIM91214.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EIM91214.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase GRDA PF04723.14 EIM91214.1 - 0.12 12.2 0.0 3 7.6 0.0 2.4 2 1 0 2 2 2 0 Glycine reductase complex selenoprotein A PH_6 PF15406.6 EIM91214.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DIOX_N PF14226.6 EIM91215.1 - 1e-18 68.2 0.0 1.6e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM91215.1 - 5.8e-16 58.8 0.0 1.3e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EIM91216.1 - 1.3e-28 100.0 35.2 1.3e-28 100.0 35.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MRP-L46 PF11788.8 EIM91216.1 - 0.015 16.0 0.0 0.05 14.3 0.0 1.8 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 PspA_IM30 PF04012.12 EIM91216.1 - 0.095 12.3 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family Peptidase_C2 PF00648.21 EIM91217.1 - 1.6e-59 201.4 2.2 9e-59 198.9 2.2 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease COX6B PF02297.17 EIM91222.1 - 4.8e-20 71.6 0.2 6e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EIM91222.1 - 0.051 13.9 0.0 0.085 13.2 0.0 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Peptidase_C14 PF00656.22 EIM91224.1 - 3.6e-41 141.7 0.0 4.3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 EIM91225.1 - 2.7e-65 220.8 0.0 3.4e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RNase_P_Rpp14 PF01900.19 EIM91227.1 - 1.3e-27 96.0 0.0 1.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Glyco_hydro_43 PF04616.14 EIM91228.1 - 3.4e-29 102.1 0.3 4.4e-29 101.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ECR1_N PF14382.6 EIM91228.1 - 0.17 11.7 1.1 5 7.0 0.1 2.9 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Glyco_hydro_32N PF00251.20 EIM91228.1 - 0.18 11.4 0.1 1.6 8.2 0.0 2.0 1 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Aminotran_1_2 PF00155.21 EIM91229.1 - 2.1e-27 96.3 0.0 2.9e-10 39.8 0.0 4.0 3 1 0 3 3 3 3 Aminotransferase class I and II SPX PF03105.19 EIM91229.1 - 4 7.2 8.8 1.4 8.8 4.8 1.9 2 0 0 2 2 2 0 SPX domain CoA_transf_3 PF02515.17 EIM91230.1 - 2.1e-59 201.5 0.0 2.6e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III ROQ_II PF18386.1 EIM91230.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Roquin II domain TOM13 PF08219.11 EIM91231.1 - 1.7e-14 53.5 0.0 5.3e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF4407 PF14362.6 EIM91231.1 - 0.042 13.2 1.9 0.13 11.5 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 EIM91231.1 - 1.6 8.5 10.0 21 4.8 0.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EIM91231.1 - 3 6.5 10.1 37 2.9 10.3 2.0 1 1 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EIM91231.1 - 3.4 6.3 10.0 0.84 8.3 4.9 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EIM91231.1 - 6.8 5.8 11.5 0.58 9.3 3.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter HIP1_clath_bdg PF16515.5 EIM91231.1 - 7.8 7.2 14.9 0.93 10.1 10.4 1.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tho2 PF11262.8 EIM91231.1 - 8.4 5.5 7.1 14 4.8 7.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Glyco_hydro_79C PF16862.5 EIM91232.1 - 4.8e-11 43.4 1.4 1.3e-10 42.1 1.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF2193 PF09959.9 EIM91232.1 - 0.22 9.9 0.0 0.39 9.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Aminotran_5 PF00266.19 EIM91233.1 - 6.7e-13 48.3 0.0 6.7e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 EIM91233.1 - 9.5e-06 25.0 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIM91233.1 - 0.006 15.9 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family GGACT PF06094.12 EIM91234.1 - 3.7e-10 40.5 0.0 4.4e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like zf-C2H2 PF00096.26 EIM91235.1 - 0.023 15.1 15.9 1.3 9.6 3.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM91235.1 - 0.13 13.2 12.5 5.6 8.1 1.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 EIM91235.1 - 1.3 9.5 4.9 4.8 7.7 1.7 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Terpene_synth_C PF03936.16 EIM91236.1 - 8.9e-06 25.2 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Aldo_ket_red PF00248.21 EIM91237.1 - 1.1e-77 261.2 0.0 1.2e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 EIM91238.1 - 1e-50 172.8 0.0 1.4e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM91238.1 - 9.7e-28 97.5 0.1 1.5e-27 96.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EIM91238.1 - 2.4e-06 26.9 0.6 5e-06 25.8 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIM91238.1 - 0.0007 18.9 0.4 0.0014 17.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM91238.1 - 0.0029 16.7 0.6 0.0047 16.1 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIM91238.1 - 0.0052 15.5 0.1 0.0086 14.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EIM91238.1 - 0.0057 16.9 0.4 0.0057 16.9 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIM91238.1 - 0.011 15.0 0.2 0.018 14.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EIM91238.1 - 0.012 15.2 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EIM91238.1 - 0.038 13.2 0.1 0.075 12.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EIM91238.1 - 0.14 12.8 0.3 0.34 11.5 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EIM91239.1 - 6.8e-32 110.8 34.5 6.8e-32 110.8 34.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EIM91240.1 - 3.5e-44 151.3 0.0 4.5e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM91241.1 - 0.0025 16.6 0.0 0.0026 16.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EIM91242.1 - 5.3e-18 65.4 0.2 3.5e-13 49.7 0.3 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EIM91242.1 - 9.6e-10 38.6 0.3 8.8e-09 35.5 0.1 2.4 3 0 0 3 3 3 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EIM91242.1 - 4.1e-05 23.8 0.2 6.4e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EIM91242.1 - 0.0002 21.5 0.1 0.0016 18.5 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EIM91242.1 - 0.0002 21.6 0.3 0.00032 20.9 0.3 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 EIM91242.1 - 0.00088 18.8 0.0 0.87 9.0 0.0 2.4 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 EIM91242.1 - 0.001 18.6 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus F420_oxidored PF03807.17 EIM91242.1 - 0.0014 19.2 0.3 0.0031 18.0 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 EIM91242.1 - 0.0073 16.0 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase KR PF08659.10 EIM91242.1 - 0.031 14.2 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 EIM91242.1 - 0.049 12.6 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_3 PF03447.16 EIM91242.1 - 0.096 13.3 0.5 1.9 9.2 0.2 2.4 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain p450 PF00067.22 EIM91243.1 - 5.2e-64 216.7 0.0 6.6e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2976 PF11190.8 EIM91243.1 - 0.11 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) GMC_oxred_N PF00732.19 EIM91244.1 - 1.4e-67 228.1 0.0 1.8e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM91244.1 - 1.3e-33 116.6 0.0 2.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Adeno_PVIII PF01310.18 EIM91244.1 - 0.02 14.5 0.0 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII Lipase_GDSL_2 PF13472.6 EIM91244.1 - 0.023 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.19 EIM91245.1 - 2.3e-20 73.1 0.0 8.1e-20 71.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EIM91245.1 - 9e-11 41.9 0.3 4.8e-06 26.4 0.2 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIM91245.1 - 3.9e-08 32.8 0.1 6.7e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM91245.1 - 1.5e-06 27.7 0.2 0.00018 20.8 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIM91245.1 - 3.1e-06 26.8 0.3 5.3e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM91245.1 - 7.1e-06 26.2 0.1 1.9e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM91245.1 - 0.00048 19.3 0.1 0.089 11.8 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 EIM91245.1 - 0.00056 20.4 0.1 0.0011 19.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM91245.1 - 0.001 17.8 0.2 0.002 16.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EIM91245.1 - 0.0015 17.8 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EIM91245.1 - 0.0026 16.9 0.6 0.0035 16.5 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EIM91245.1 - 0.0082 15.4 0.1 0.02 14.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EIM91245.1 - 0.085 11.7 0.0 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EIM91245.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EIM91245.1 - 0.31 10.9 0.9 1.3 8.9 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 EIM91246.1 - 7.4e-24 84.1 0.9 1.3e-23 83.3 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.21 EIM91247.1 - 2.6e-80 269.8 0.0 2.9e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 EIM91248.1 - 8.8e-68 229.1 0.0 1.1e-67 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 EIM91250.1 - 0.079 13.4 15.1 0.79 10.3 2.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM91250.1 - 0.2 12.6 13.1 2.8 9.0 1.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIM91250.1 - 0.36 10.6 3.7 1 9.1 3.7 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-met PF12874.7 EIM91250.1 - 0.38 11.2 2.8 1.5 9.3 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EIM91250.1 - 0.59 10.7 6.0 0.8 10.2 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Hva1_TUDOR PF11160.8 EIM91254.1 - 2e-13 50.3 10.4 1.7e-05 24.9 0.4 4.5 3 2 0 3 3 3 2 Hypervirulence associated proteins TUDOR domain DUF1918 PF08940.11 EIM91254.1 - 4.3e-06 26.2 0.6 0.048 13.3 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1918) Tudor_RapA PF18337.1 EIM91254.1 - 0.0037 17.4 6.2 0.12 12.6 0.2 3.2 4 0 0 4 4 4 2 RapA N-terminal Tudor like domain MCLC PF05934.11 EIM91254.1 - 0.014 14.1 0.9 0.26 10.0 0.3 1.9 1 1 1 2 2 2 0 Mid-1-related chloride channel (MCLC) Rhabdo_matrix PF03397.14 EIM91254.1 - 0.02 14.6 0.9 1.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Rhabdovirus matrix protein MtrD PF04207.12 EIM91254.1 - 0.026 14.2 0.3 7 6.3 0.0 2.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit D Biotin_lipoyl PF00364.22 EIM91254.1 - 0.17 11.7 1.8 34 4.4 0.0 3.4 4 0 0 4 4 4 0 Biotin-requiring enzyme Tetradecapep PF08187.11 EIM91254.1 - 0.32 11.1 3.9 13 6.1 0.3 2.5 2 0 0 2 2 2 0 Myoactive tetradecapeptides family Phage_holin_3_6 PF07332.11 EIM91255.1 - 0.09 12.8 0.0 0.09 12.8 0.0 2.9 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF155 PF02582.14 EIM91256.1 - 7.3e-46 156.5 0.0 1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 F-box-like PF12937.7 EIM91257.1 - 0.0091 15.9 0.1 0.032 14.1 0.1 2.1 1 0 0 1 1 1 1 F-box-like PRK PF00485.18 EIM91258.1 - 1.9e-50 171.4 0.0 2.8e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EIM91258.1 - 5.5e-44 150.1 0.0 9.1e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EIM91258.1 - 0.00011 22.8 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIM91258.1 - 0.0011 19.1 0.0 0.0037 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EIM91258.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Peptidase_A25 PF03418.14 EIM91258.1 - 0.083 11.8 0.0 2.7 6.8 0.0 2.1 1 1 1 2 2 2 0 Germination protease AAA_17 PF13207.6 EIM91258.1 - 0.17 12.3 1.8 0.96 9.9 0.7 2.5 2 1 0 2 2 2 0 AAA domain CoaE PF01121.20 EIM91258.1 - 0.25 11.0 4.6 0.21 11.3 1.3 2.4 2 1 0 2 2 2 0 Dephospho-CoA kinase APG17 PF04108.12 EIM91259.1 - 3e-66 224.2 7.0 3.8e-66 223.8 7.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF3447 PF11929.8 EIM91259.1 - 0.018 15.0 0.3 0.036 14.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) KxDL PF10241.9 EIM91259.1 - 0.054 13.8 4.6 1.6 9.1 0.9 3.8 3 1 0 3 3 3 0 Uncharacterized conserved protein Arch_fla_DE PF04659.13 EIM91259.1 - 0.062 13.2 0.0 0.062 13.2 0.0 2.3 3 0 0 3 3 3 0 Archaeal flagella protein NifQ PF04891.12 EIM91259.1 - 0.11 12.9 1.4 0.32 11.3 1.4 1.8 1 0 0 1 1 1 0 NifQ NPV_P10 PF05531.12 EIM91259.1 - 0.69 10.4 7.5 6.8 7.2 0.1 4.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein YjcZ PF13990.6 EIM91259.1 - 1.9 7.8 5.8 15 4.9 0.7 2.8 3 0 0 3 3 3 0 YjcZ-like protein UPF0184 PF03670.13 EIM91259.1 - 2.4 8.6 10.2 4 7.9 0.0 4.2 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0184) Bacillus_HBL PF05791.11 EIM91259.1 - 3.6 7.4 5.9 0.95 9.3 0.7 2.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ADH_N PF08240.12 EIM91260.1 - 2.6e-11 43.3 0.2 6.9e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM91260.1 - 2.7e-11 43.6 0.0 4.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM91260.1 - 0.00091 20.3 0.0 0.0028 18.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91261.1 - 6e-12 45.4 0.2 1.4e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM91261.1 - 9.4e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM91261.1 - 0.0029 18.7 0.0 0.0091 17.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase GPI-anchored PF10342.9 EIM91262.1 - 6.2e-09 36.5 0.5 6.2e-09 36.5 0.5 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ceramidase PF05875.12 EIM91264.1 - 3.2e-78 262.8 12.9 3.8e-78 262.6 12.9 1.0 1 0 0 1 1 1 1 Ceramidase DUF2516 PF10724.9 EIM91264.1 - 0.66 10.3 4.3 0.54 10.6 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) MerC PF03203.14 EIM91264.1 - 5.7 7.4 11.1 65 4.0 6.5 2.9 1 1 1 2 2 2 0 MerC mercury resistance protein DUF3421 PF11901.8 EIM91265.1 - 6e-28 97.2 0.2 9.4e-28 96.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Rot1 PF10681.9 EIM91266.1 - 8.2e-56 188.8 0.2 9.9e-56 188.6 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal WLM PF08325.10 EIM91267.1 - 7.9e-30 104.3 7.6 1e-29 104.0 0.8 2.9 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 EIM91267.1 - 1.6e-05 25.0 0.1 2.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 EIM91267.1 - 0.0009 18.5 0.4 0.0016 17.7 0.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprT-like PF10263.9 EIM91267.1 - 0.015 15.2 0.1 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 EIM91267.1 - 0.088 13.1 0.4 0.67 10.3 0.0 2.3 2 0 0 2 2 2 0 Effector protein Vps36-NZF-N PF16988.5 EIM91267.1 - 1 8.8 2.6 3.8 7.0 2.6 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PFK PF00365.20 EIM91268.1 - 5.2e-182 603.5 0.0 6e-98 327.7 0.0 2.7 2 1 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EIM91268.1 - 0.14 11.7 0.1 0.42 10.2 0.1 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Arylesterase PF01731.20 EIM91269.1 - 2.5e-06 27.6 0.1 0.057 13.6 0.0 2.6 2 0 0 2 2 2 2 Arylesterase Str_synth PF03088.16 EIM91269.1 - 0.0026 17.8 0.0 0.0083 16.2 0.0 1.8 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 EIM91269.1 - 0.099 12.2 0.0 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region MFS_1 PF07690.16 EIM91270.1 - 1.3e-26 93.4 52.7 1.9e-24 86.3 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.9 EIM91270.1 - 0.067 13.6 5.0 1.5 9.3 0.2 3.5 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Tetraspanin PF00335.20 EIM91270.1 - 8.1 6.1 11.5 44 3.7 0.1 3.2 2 1 0 2 2 2 0 Tetraspanin family CaM_bdg_C0 PF10562.9 EIM91271.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Gp58 PF07902.11 EIM91273.1 - 0.072 11.4 9.1 0.11 10.8 0.2 2.8 2 1 0 2 2 2 0 gp58-like protein Spc7 PF08317.11 EIM91273.1 - 1.7 7.4 76.4 1.5 7.7 22.1 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 EIM91273.1 - 5.2 6.6 47.8 0.46 10.0 6.5 3.0 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 EIM91273.1 - 6 7.4 12.7 4.9 7.7 0.8 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 EIM91273.1 - 8 6.5 79.1 2.4 8.2 11.3 5.7 2 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Alpha-amylase PF00128.24 EIM91274.1 - 7.4e-27 94.8 1.8 2.1e-26 93.3 1.8 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EIM91274.1 - 0.00011 20.6 0.1 0.1 10.8 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Adhesin_P1_N PF18652.1 EIM91274.1 - 0.042 13.9 0.2 0.097 12.7 0.2 1.6 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain F-box-like PF12937.7 EIM91275.1 - 1.8e-07 30.9 1.5 5e-07 29.5 1.5 1.8 1 0 0 1 1 1 1 F-box-like Formyl_trans_N PF00551.19 EIM91276.1 - 7.8e-25 87.7 0.0 1.2e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EIM91276.1 - 6.8e-10 39.1 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Thioredoxin PF00085.20 EIM91277.1 - 3e-56 187.7 0.0 8e-28 96.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EIM91277.1 - 5.2e-25 88.2 0.8 1.4e-24 86.8 0.8 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EIM91277.1 - 6.7e-16 58.7 0.0 5.1e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EIM91277.1 - 2.9e-11 43.3 0.0 5.7e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EIM91277.1 - 3e-09 36.9 0.0 0.004 17.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EIM91277.1 - 1.3e-08 35.1 0.1 0.033 14.5 0.0 4.2 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.6 EIM91277.1 - 4.2e-08 33.3 0.0 0.24 11.3 0.0 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.21 EIM91277.1 - 6.7e-07 29.3 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 EIM91277.1 - 2.4e-05 24.3 0.0 0.051 13.4 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Glutaredoxin PF00462.24 EIM91277.1 - 6e-05 23.2 0.6 0.0061 16.8 0.2 3.1 2 1 0 2 2 2 1 Glutaredoxin Redoxin PF08534.10 EIM91277.1 - 0.00097 18.9 0.3 1.6 8.5 0.1 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 EIM91277.1 - 0.0021 17.8 0.3 1.8 8.4 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin HyaE PF07449.11 EIM91277.1 - 0.0079 16.2 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 EIM91277.1 - 0.017 14.9 4.2 28 4.4 0.1 4.7 3 2 2 5 5 5 0 DSBA-like thioredoxin domain DDE_Tnp_1_2 PF13586.6 EIM91277.1 - 0.068 13.6 0.0 5.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain DUF503 PF04456.12 EIM91277.1 - 0.24 11.3 2.0 3.4 7.6 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF503) Thioredoxin_4 PF13462.6 EIM91277.1 - 0.45 10.6 4.0 17 5.6 0.1 3.1 3 1 0 3 3 3 0 Thioredoxin DUF4141 PF13605.6 EIM91278.1 - 0.0022 17.2 0.2 0.012 14.9 0.2 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4141) SOG2 PF10428.9 EIM91279.1 - 9.9 5.2 23.8 12 4.9 23.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 EIM91280.1 - 7.1e-34 117.3 36.2 7.1e-34 117.3 36.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily AXIN1_TNKS_BD PF16646.5 EIM91280.1 - 0.15 13.0 0.0 0.29 12.1 0.0 1.3 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain FPN1 PF06963.12 EIM91281.1 - 5.2e-125 417.4 12.7 6.1e-125 417.2 12.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Mad3_BUB1_I PF08311.12 EIM91282.1 - 1.9e-30 105.4 0.0 3.3e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EIM91282.1 - 1.7e-12 47.2 0.0 5.6e-12 45.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 EIM91282.1 - 1.8e-06 28.0 0.0 4.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 EIM91282.1 - 4.8e-06 26.1 0.0 7.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-B_dimeris PF09026.10 EIM91282.1 - 0.00095 19.5 1.7 0.00095 19.5 1.7 2.5 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Voldacs PF03517.13 EIM91282.1 - 1.5 9.0 7.4 9.8 6.3 0.4 2.7 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Sigma70_ner PF04546.13 EIM91282.1 - 2.6 7.9 7.0 0.3 10.9 0.2 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region TLP-20 PF06088.11 EIM91282.1 - 2.9 7.8 4.8 27 4.6 0.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SDA1 PF05285.12 EIM91282.1 - 4.6 6.6 9.2 2.4 7.5 0.8 2.4 2 0 0 2 2 2 0 SDA1 RXT2_N PF08595.11 EIM91282.1 - 9 6.3 9.9 2.5 8.1 0.6 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4246 PF14033.6 EIM91283.1 - 7.6e-135 450.5 0.2 9.2e-135 450.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) MIP PF00230.20 EIM91284.1 - 9.2e-29 100.8 9.2 1.4e-28 100.1 9.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF3487 PF11990.8 EIM91284.1 - 5.1 7.0 9.2 0.66 9.9 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) LsmAD PF06741.13 EIM91286.1 - 4.3e-26 91.3 2.9 9.8e-26 90.1 2.9 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 EIM91286.1 - 0.0029 17.7 0.1 0.006 16.7 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EIM91286.1 - 0.023 14.8 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain Epimerase PF01370.21 EIM91287.1 - 1.1e-20 74.1 0.1 3.9e-20 72.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIM91287.1 - 1.1e-09 38.2 0.1 2.4e-09 37.0 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM91287.1 - 2.9e-09 36.5 0.2 2.7e-05 23.5 0.1 2.5 3 0 0 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 EIM91287.1 - 3.9e-09 36.7 0.2 6.8e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIM91287.1 - 5.5e-09 35.4 0.0 1.1e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EIM91287.1 - 9.2e-06 25.4 0.2 1.5e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EIM91287.1 - 0.00024 20.4 0.0 0.003 16.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EIM91287.1 - 0.0048 16.4 0.8 0.029 13.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Arylesterase PF01731.20 EIM91288.1 - 4.6e-05 23.5 0.6 0.0025 18.0 0.6 2.7 1 1 0 1 1 1 1 Arylesterase SGL PF08450.12 EIM91288.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EIM91288.1 - 0.22 11.7 0.0 0.49 10.6 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase BRO1 PF03097.18 EIM91289.1 - 2.5e-100 336.0 0.1 5.4e-100 334.9 0.1 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EIM91289.1 - 1.7e-73 247.5 5.1 1.7e-73 247.5 5.1 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF16 PF01519.16 EIM91289.1 - 0.2 12.2 1.8 0.36 11.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 HAUS2 PF15003.6 EIM91289.1 - 1.3 8.7 4.3 0.76 9.5 0.1 2.6 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 2 Syntaxin-6_N PF09177.11 EIM91289.1 - 4.2 8.0 8.6 25 5.5 2.5 3.8 2 1 2 4 4 4 0 Syntaxin 6, N-terminal RasGAP PF00616.19 EIM91291.1 - 5e-60 202.8 0.7 1.7e-59 201.0 0.0 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EIM91291.1 - 3.2e-36 124.5 0.4 3.2e-36 124.5 0.4 2.1 2 0 0 2 2 2 1 RasGAP C-terminus Glyco_transf_20 PF00982.21 EIM91292.1 - 3.5e-180 599.7 0.0 9.4e-140 466.4 0.0 1.9 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 EIM91292.1 - 0.00029 21.3 0.0 0.0007 20.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EIM91292.1 - 0.01 15.4 0.1 0.93 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 MIF4G PF02854.19 EIM91293.1 - 3e-56 190.4 0.6 4.1e-56 190.0 0.6 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EIM91293.1 - 3.2e-18 65.7 0.0 6.5e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 EIM91293.1 - 0.018 15.0 0.1 0.091 12.7 0.0 2.1 2 0 0 2 2 2 0 MA3 domain DUF445 PF04286.12 EIM91293.1 - 0.45 10.3 5.6 1.4 8.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) HD PF01966.22 EIM91295.1 - 0.00019 21.6 1.0 0.0019 18.4 0.2 2.6 2 1 0 2 2 2 1 HD domain Zip PF02535.22 EIM91296.1 - 2.7e-50 171.5 19.5 1.1e-44 153.0 11.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter NUDIX PF00293.28 EIM91297.1 - 3.2e-13 49.8 0.4 4e-13 49.6 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain DNA_pol3_delta2 PF13177.6 EIM91298.1 - 7.7e-13 48.5 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EIM91298.1 - 9.7e-06 26.0 0.3 2.7e-05 24.6 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIM91298.1 - 0.0096 16.3 0.2 0.039 14.3 0.1 2.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM91298.1 - 0.01 16.1 0.8 0.63 10.3 0.7 3.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EIM91298.1 - 0.027 14.6 0.2 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 EIM91298.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA C-terminal domain TSC21 PF15217.6 EIM91298.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 TSC21 family Mg_chelatase PF01078.21 EIM91298.1 - 0.093 12.1 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EIM91298.1 - 0.097 12.4 0.3 0.27 11.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EIM91298.1 - 0.1 12.6 0.3 0.25 11.3 0.3 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Prenyltransf PF01255.19 EIM91298.1 - 0.17 11.4 0.9 0.33 10.4 0.9 1.5 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase DUF2795 PF11387.8 EIM91300.1 - 0.037 14.3 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) DUF2370 PF10176.9 EIM91301.1 - 5.7e-49 166.8 0.0 1e-48 166.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) TMEM51 PF15345.6 EIM91301.1 - 0.00071 19.5 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 CD52 PF15116.6 EIM91301.1 - 0.34 11.0 3.2 0.53 10.4 0.3 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen Methyltransf_23 PF13489.6 EIM91302.1 - 0.00083 19.2 0.0 0.0025 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain ATP_synt_H PF05493.13 EIM91303.1 - 2.4e-21 76.0 6.9 2.9e-21 75.7 6.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Saf_2TM PF18303.1 EIM91303.1 - 0.004 16.8 0.4 0.0047 16.5 0.4 1.2 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain MgtE PF01769.16 EIM91303.1 - 0.13 12.6 3.7 0.14 12.5 3.7 1.0 1 0 0 1 1 1 0 Divalent cation transporter DUF4131 PF13567.6 EIM91303.1 - 0.39 10.3 4.1 0.42 10.3 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MIF4G PF02854.19 EIM91304.1 - 4.8e-30 104.8 0.0 5.6e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain zf-C3HC PF07967.13 EIM91305.1 - 2.3e-22 79.5 0.0 5.8e-21 74.9 0.0 2.9 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 EIM91305.1 - 2.1e-12 47.0 0.7 0.0018 18.4 0.0 4.2 4 0 0 4 4 4 3 Rsm1-like DM PF00751.18 EIM91305.1 - 0.047 13.6 0.5 5.7 6.9 0.1 2.6 2 0 0 2 2 2 0 DM DNA binding domain MIF4G PF02854.19 EIM91308.1 - 3.7e-28 98.6 0.0 4.8e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain YniB PF14002.6 EIM91308.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 YniB-like protein Glyco_hydro_1 PF00232.18 EIM91310.1 - 6.8e-107 357.7 1.3 9.2e-107 357.3 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Casein_kappa PF00997.18 EIM91310.1 - 0.46 10.6 6.3 0.97 9.5 6.3 1.5 1 0 0 1 1 1 0 Kappa casein p450 PF00067.22 EIM91312.1 - 8e-71 239.2 0.0 1.1e-70 238.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.19 EIM91313.1 - 5.5e-46 157.4 0.0 1.7e-45 155.8 0.0 1.8 1 1 0 1 1 1 1 RNB domain zf-C2H2_2 PF12756.7 EIM91314.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Aldo_ket_red PF00248.21 EIM91315.1 - 2.7e-52 177.8 0.0 3.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4258 PF14076.6 EIM91315.1 - 0.094 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Pkinase PF00069.25 EIM91316.1 - 8.5e-41 140.1 0.0 2.8e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91316.1 - 3.1e-19 69.3 0.0 1.3e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIM91316.1 - 3.4e-05 23.3 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIM91316.1 - 0.022 14.7 0.0 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 EIM91317.1 - 3.9e-10 39.2 0.0 7.2e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM91317.1 - 2e-07 31.0 11.2 3.3e-07 30.3 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps51 PF08700.11 EIM91319.1 - 1.1e-23 83.1 1.9 1.6e-23 82.6 1.9 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EIM91319.1 - 0.00085 19.5 4.4 0.0013 18.9 4.4 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 EIM91319.1 - 0.0012 17.6 2.4 0.0016 17.2 2.4 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.12 EIM91319.1 - 0.013 16.0 1.7 0.019 15.5 1.7 1.2 1 0 0 1 1 1 0 FlgN protein Tmemb_cc2 PF10267.9 EIM91319.1 - 0.049 12.8 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1087 PF06465.13 EIM91322.1 - 0.04 13.9 0.4 0.15 12.1 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1087) Metallophos PF00149.28 EIM91323.1 - 2.2e-10 41.4 0.0 4.2e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EIM91323.1 - 0.0018 16.7 0.0 0.0036 15.7 0.0 1.5 1 0 0 1 1 1 1 Firmicute fructose-1,6-bisphosphatase PRMT5_TIM PF17285.2 EIM91324.1 - 1.2e-68 231.1 0.0 1.6e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EIM91324.1 - 3.9e-63 212.4 0.0 6.7e-63 211.6 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EIM91324.1 - 2.6e-58 196.8 0.0 3.7e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 EIM91324.1 - 0.023 15.4 0.0 0.053 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ABM PF03992.16 EIM91324.1 - 0.088 12.9 0.4 0.21 11.7 0.4 1.6 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Met_10 PF02475.16 EIM91324.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ank_4 PF13637.6 EIM91325.1 - 0.0069 17.0 0.0 0.29 11.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FlxA PF14282.6 EIM91325.1 - 0.13 12.3 14.4 1.5 8.9 0.3 3.7 2 1 0 3 3 3 0 FlxA-like protein MMPL PF03176.15 EIM91325.1 - 0.34 9.8 1.3 0.65 8.9 1.3 1.4 1 0 0 1 1 1 0 MMPL family Fez1 PF06818.15 EIM91325.1 - 0.55 10.7 24.1 0.071 13.6 18.2 2.5 2 1 0 2 2 2 0 Fez1 FlaC_arch PF05377.11 EIM91325.1 - 1.4 9.3 9.7 9.5 6.7 0.3 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 EIM91325.1 - 5.4 7.4 13.2 2.1 8.7 5.4 3.0 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) CorA PF01544.18 EIM91325.1 - 5.5 6.2 10.5 3.6 6.8 3.5 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Spc7 PF08317.11 EIM91325.1 - 6.3 5.6 26.3 2.8 6.8 10.5 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EIM91325.1 - 9.4 6.6 19.5 19 5.6 0.4 4.9 3 1 0 4 4 4 0 ABC transporter C-terminal domain GATA PF00320.27 EIM91326.1 - 6e-14 51.4 2.9 1.3e-13 50.2 2.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 EIM91326.1 - 0.00032 20.9 0.0 0.00077 19.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EIM91326.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EIM91326.1 - 0.061 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold LRR_4 PF12799.7 EIM91327.1 - 3.1e-40 135.5 33.2 4.6e-08 33.2 0.3 7.3 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM91327.1 - 3.1e-29 100.5 32.0 7.4e-11 41.6 2.8 6.5 2 2 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 EIM91327.1 - 2.6e-25 88.9 12.2 2.8e-10 40.0 1.8 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EIM91327.1 - 7.5e-06 25.8 32.6 3.9 8.4 0.2 10.6 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 EIM91327.1 - 5e-05 23.0 28.2 2.1 8.6 0.3 8.8 11 0 0 11 11 11 4 Leucine Rich repeat LRR_12 PF18837.1 EIM91327.1 - 0.78 9.4 3.5 31 4.3 0.1 3.7 4 0 0 4 4 4 0 Leucine-rich repeat DUF4078 PF13300.6 EIM91328.1 - 1.7e-18 66.7 4.3 1.7e-18 66.7 4.3 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4078) MFS_1 PF07690.16 EIM91329.1 - 1.9e-24 86.3 27.1 1.9e-24 86.3 27.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 EIM91330.1 - 3.6e-15 56.7 0.0 9.6e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM91330.1 - 9.7e-12 45.3 0.1 1.8e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.21 EIM91332.1 - 5.9e-22 78.3 1.3 4e-21 75.6 1.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM91332.1 - 6.9e-17 61.4 0.0 9.6e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIM91332.1 - 3.1e-14 52.8 0.6 4.1e-13 49.1 0.6 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIM91332.1 - 2.2e-13 50.3 0.0 2.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIM91332.1 - 1.3e-11 44.7 0.1 1.9e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIM91332.1 - 3e-06 27.0 0.4 5.3e-06 26.2 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EIM91332.1 - 2e-05 23.9 0.2 0.16 11.0 0.2 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 EIM91332.1 - 2.1e-05 24.1 3.6 0.0011 18.4 0.5 3.0 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM91332.1 - 0.00066 18.9 0.1 0.0019 17.4 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Med26 PF08711.11 EIM91333.1 - 1.1e-09 38.1 0.1 4.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain HATPase_c PF02518.26 EIM91334.1 - 3.2e-39 133.9 0.0 3.2e-18 66.3 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIM91334.1 - 1.4e-36 125.1 0.2 2.7e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EIM91334.1 - 1.7e-19 69.6 2.1 1.4e-10 41.0 0.0 3.2 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EIM91334.1 - 5.7e-07 29.5 0.0 0.00044 20.1 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 EIM91334.1 - 0.00015 21.7 0.1 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 PAS domain HATPase_c_5 PF14501.6 EIM91334.1 - 0.00092 19.1 0.0 0.079 12.9 0.0 2.6 3 0 0 3 3 3 1 GHKL domain HATPase_c_2 PF13581.6 EIM91334.1 - 0.0027 17.7 0.0 0.69 9.9 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_3 PF08447.12 EIM91334.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 EIM91334.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.9 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 EIM91334.1 - 0.063 13.5 0.1 0.58 10.4 0.0 2.8 4 0 0 4 4 4 0 PAS fold IucA_IucC PF04183.12 EIM91335.1 - 1.7e-22 80.2 0.2 6.7e-22 78.2 0.2 1.9 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EIM91335.1 - 1.7e-11 44.8 0.0 3.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 EIM91336.1 - 4.2e-21 75.6 0.0 7.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EIM91336.1 - 1.5e-08 35.2 0.4 6.7e-08 33.1 0.4 2.1 1 1 0 1 1 1 1 Ferric iron reductase FhuF-like transporter DUF4646 PF15496.6 EIM91337.1 - 2.4e-07 31.4 0.2 2.4e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) CS PF04969.16 EIM91338.1 - 2.1e-07 31.8 0.0 4.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 CS domain Sel1 PF08238.12 EIM91338.1 - 0.0076 16.9 0.8 2.1 9.2 0.0 2.7 2 0 0 2 2 2 2 Sel1 repeat TPR_8 PF13181.6 EIM91338.1 - 0.018 15.2 0.3 4 7.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM91338.1 - 0.22 11.7 0.3 3.8 7.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Cu-oxidase_3 PF07732.15 EIM91340.1 - 2.7e-45 153.2 3.6 1e-43 148.2 1.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM91340.1 - 7.3e-37 126.2 2.6 2.2e-31 108.4 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EIM91340.1 - 2.6e-28 99.2 1.7 2e-25 89.8 0.3 3.2 3 0 0 3 3 3 2 Multicopper oxidase C2 PF00168.30 EIM91341.1 - 2.8e-13 50.0 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain Abhydrolase_1 PF00561.20 EIM91342.1 - 5.9e-05 22.8 0.0 0.00016 21.4 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIM91342.1 - 0.00024 20.5 0.0 0.00056 19.2 0.0 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EIM91342.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) VirJ PF06057.11 EIM91342.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF1749 PF08538.10 EIM91342.1 - 0.12 11.4 0.0 1.1 8.3 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1749) Cation_ATPase_C PF00689.21 EIM91343.1 - 1.6e-46 158.3 4.7 1.6e-46 158.3 4.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EIM91343.1 - 3.8e-36 124.3 0.2 3.8e-36 124.3 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EIM91343.1 - 2.3e-19 69.2 0.0 5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EIM91343.1 - 2.5e-14 54.1 6.2 1.8e-13 51.3 6.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIM91343.1 - 6.8e-10 38.5 0.1 2.3e-09 36.8 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIM91343.1 - 2.9e-05 23.9 0.4 0.0056 16.4 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase YopE PF03545.13 EIM91344.1 - 0.12 12.5 0.8 0.31 11.2 0.8 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) MFS_1 PF07690.16 EIM91345.1 - 4.6e-38 131.1 19.4 4.6e-38 131.1 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM91345.1 - 2.4e-14 53.1 3.6 2.4e-14 53.1 3.6 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EIM91345.1 - 0.0027 16.2 3.3 0.0027 16.2 3.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CALCOCO1 PF07888.11 EIM91349.1 - 0.00075 18.5 11.0 0.0011 17.9 11.0 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 EIM91349.1 - 0.014 15.4 7.6 0.034 14.2 7.6 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 EIM91349.1 - 0.045 14.0 3.7 1.1 9.6 0.1 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.9 EIM91349.1 - 0.046 12.7 7.3 0.17 10.8 7.1 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Dynamitin PF04912.14 EIM91349.1 - 0.05 12.9 9.3 1.5 8.0 0.2 2.1 1 1 1 2 2 2 0 Dynamitin HsbA PF12296.8 EIM91349.1 - 0.059 13.8 1.6 0.6 10.6 2.0 2.2 1 1 0 1 1 1 0 Hydrophobic surface binding protein A TMCO5 PF14992.6 EIM91349.1 - 0.06 12.9 6.3 0.1 12.1 6.3 1.3 1 0 0 1 1 1 0 TMCO5 family Cob_adeno_trans PF01923.18 EIM91349.1 - 0.13 12.4 0.8 0.31 11.2 0.8 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3829 PF12889.7 EIM91349.1 - 0.21 11.0 2.9 1.6 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) OmpH PF03938.14 EIM91349.1 - 0.25 11.7 4.1 0.47 10.8 4.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 EIM91349.1 - 0.26 11.8 4.5 0.73 10.3 0.4 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EIM91349.1 - 0.31 11.7 1.8 0.94 10.2 1.8 1.9 1 0 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 EIM91349.1 - 0.36 10.1 6.5 0.61 9.4 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Flagellin_N PF00669.20 EIM91349.1 - 0.43 10.7 9.1 0.29 11.3 4.2 2.3 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Tup_N PF08581.10 EIM91349.1 - 0.49 10.7 7.5 0.2 12.0 0.6 2.6 1 1 1 2 2 2 0 Tup N-terminal JAKMIP_CC3 PF16034.5 EIM91349.1 - 0.53 10.2 10.6 1.8 8.5 10.6 1.8 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF4763 PF15960.5 EIM91349.1 - 1.1 8.5 9.6 2.1 7.6 9.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Atg14 PF10186.9 EIM91349.1 - 1.4 8.0 11.1 2.8 6.9 11.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 EIM91349.1 - 2.6 7.3 5.8 4.8 6.4 5.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EIM91349.1 - 5.2 7.1 8.6 63 3.6 8.7 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 EIM91349.1 - 7.4 6.6 12.7 14 5.7 11.5 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 EIM91349.1 - 8.8 6.7 10.9 27 5.2 10.6 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Oxidored_molyb PF00174.19 EIM91350.1 - 1.5e-55 187.4 0.0 2.3e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EIM91350.1 - 8.3e-07 29.1 0.2 2.3e-05 24.4 0.2 2.4 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Glyco_hydro_18 PF00704.28 EIM91351.1 - 3.8e-22 79.4 5.3 8.7e-22 78.2 5.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 F-box-like PF12937.7 EIM91352.1 - 0.0073 16.2 0.2 0.027 14.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like Maf1 PF09174.10 EIM91353.1 - 1.4e-39 136.0 0.0 6.8e-33 114.3 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator DAO PF01266.24 EIM91354.1 - 1.7e-43 149.6 0.1 1.9e-43 149.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM91354.1 - 0.00011 22.3 0.0 0.00054 20.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM91354.1 - 0.00031 20.1 0.1 0.096 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM91354.1 - 0.00042 20.8 0.8 0.31 11.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM91354.1 - 0.00071 18.9 0.0 0.0057 16.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM91354.1 - 0.007 16.4 0.2 0.54 10.2 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 EIM91354.1 - 0.0094 14.8 0.0 0.023 13.5 0.0 1.6 2 0 0 2 2 2 1 MCRA family Thi4 PF01946.17 EIM91354.1 - 0.015 14.5 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EIM91354.1 - 0.016 14.3 0.4 0.075 12.1 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EIM91354.1 - 0.049 12.9 0.2 0.52 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EIM91354.1 - 0.11 11.1 0.0 0.75 8.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.6 EIM91354.1 - 0.14 11.3 0.1 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AA_permease PF00324.21 EIM91355.1 - 2.2e-125 419.0 38.8 2.7e-125 418.7 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIM91355.1 - 1.5e-32 112.9 42.8 2e-32 112.5 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 EIM91356.1 - 9.9e-32 110.2 17.4 9.9e-32 110.2 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM91356.1 - 1.1e-12 47.5 3.6 1.1e-12 47.5 3.6 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EIM91356.1 - 0.0003 19.3 3.5 0.0003 19.3 3.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EIM91357.1 - 1.9e-25 89.5 41.4 6.7e-22 77.9 17.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM91357.1 - 0.0025 16.3 3.6 0.035 12.5 2.4 2.4 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fzo_mitofusin PF04799.13 EIM91357.1 - 1.2 8.7 2.7 2.5 7.6 0.3 2.4 3 0 0 3 3 3 0 fzo-like conserved region CPP1-like PF11833.8 EIM91357.1 - 8 6.1 6.1 4 7.0 2.7 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_1 PF07690.16 EIM91358.1 - 1.1e-07 31.2 13.0 0.0002 20.4 3.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM91358.1 - 0.017 14.0 0.1 0.017 14.0 0.1 1.8 2 0 0 2 2 2 0 Sugar (and other) transporter HTH_Tnp_4 PF13613.6 EIM91358.1 - 0.076 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Serglycin PF04360.12 EIM91359.1 - 0.12 12.3 4.3 0.24 11.3 4.3 1.4 1 0 0 1 1 1 0 Serglycin Ctf8 PF09696.10 EIM91360.1 - 2.7e-17 63.4 0.6 6.4e-15 55.7 0.0 2.0 1 1 1 2 2 2 2 Ctf8 YTH PF04146.15 EIM91361.1 - 8.1e-55 185.3 0.1 2e-54 184.0 0.0 1.7 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 EIM91361.1 - 8.9e-06 25.4 0.0 0.0081 16.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.25 EIM91362.1 - 3.7e-07 30.1 0.0 2.5e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EIM91362.1 - 0.0072 16.9 0.3 0.022 15.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM91362.1 - 0.073 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EIM91362.1 - 0.1 12.3 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EIM91362.1 - 0.2 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Mito_carr PF00153.27 EIM91363.1 - 7.6e-55 182.8 2.4 1.3e-20 73.1 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein ATG22 PF11700.8 EIM91364.1 - 4.9e-120 401.4 26.6 5.6e-120 401.2 26.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF962 PF06127.11 EIM91364.1 - 0.059 13.5 3.1 0.43 10.7 0.0 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF962) TssN PF17555.2 EIM91364.1 - 1.2 8.4 23.0 0.93 8.8 10.2 3.7 2 1 1 3 3 3 0 Type VI secretion system, TssN Mitofilin PF09731.9 EIM91366.1 - 1.7e-110 370.8 18.6 2.3e-110 370.3 18.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ApoLp-III PF07464.11 EIM91366.1 - 0.0073 16.4 3.4 0.0073 16.4 3.4 2.6 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF1464 PF07318.12 EIM91366.1 - 0.97 8.5 3.9 0.63 9.1 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) DUF1664 PF07889.12 EIM91366.1 - 1.4 9.0 5.7 4.1 7.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 EIM91367.1 - 0.027 14.3 0.1 0.062 13.1 0.1 1.6 1 0 0 1 1 1 0 USP8 interacting TPX2 PF06886.11 EIM91367.1 - 0.029 14.6 3.2 0.063 13.5 3.2 1.5 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) PspA_IM30 PF04012.12 EIM91367.1 - 0.032 13.8 5.5 0.057 13.0 5.5 1.4 1 0 0 1 1 1 0 PspA/IM30 family DivIC PF04977.15 EIM91367.1 - 0.06 13.1 3.2 0.14 12.0 3.2 1.6 1 0 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.9 EIM91367.1 - 0.087 13.1 1.7 0.17 12.2 1.7 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Val_tRNA-synt_C PF10458.9 EIM91367.1 - 0.2 12.0 2.1 0.41 11.0 2.1 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm ABC_tran_Xtn PF12848.7 EIM91367.1 - 0.34 11.0 5.9 0.7 10.0 5.9 1.5 1 0 0 1 1 1 0 ABC transporter DOR PF14839.6 EIM91367.1 - 0.9 9.4 7.6 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 DOR family Nucleoporin_FG PF13634.6 EIM91368.1 - 4.8e-28 97.8 135.8 4.3e-11 43.5 36.4 5.3 1 1 4 5 5 5 5 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 EIM91368.1 - 2.4e-11 42.9 39.8 2.8e-11 42.7 39.2 1.4 1 1 0 1 1 1 1 Nucleoporin FG repeated region V_ATPase_I PF01496.19 EIM91368.1 - 0.0021 16.1 1.6 0.0021 16.1 1.6 1.4 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family G3P_antiterm PF04309.12 EIM91368.1 - 0.068 12.6 0.3 0.14 11.6 0.3 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator SCAB-Ig PF16709.5 EIM91368.1 - 0.076 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Coagulase PF08764.10 EIM91368.1 - 0.32 11.1 2.0 0.53 10.4 1.5 1.5 1 1 1 2 2 2 0 Staphylococcus aureus coagulase Trehalase PF01204.18 EIM91370.1 - 9.4e-166 552.6 0.0 1.2e-165 552.3 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EIM91370.1 - 2.5e-15 55.9 0.4 4.3e-15 55.1 0.4 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cation_efflux PF01545.21 EIM91371.1 - 7e-20 71.6 9.4 8.6e-20 71.3 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EIM91371.1 - 2.6e-09 37.1 0.0 5.3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Lipase_3 PF01764.25 EIM91372.1 - 4.6e-06 26.5 0.0 2.1e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EIM91372.1 - 0.013 16.1 0.2 0.099 13.2 0.7 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 EIM91372.1 - 0.066 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 EIM91372.1 - 0.089 12.4 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EIM91372.1 - 0.21 11.3 0.1 0.5 10.0 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein MFS_1 PF07690.16 EIM91373.1 - 1.4e-31 109.8 39.5 1.9e-24 86.3 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM91373.1 - 3.9e-22 78.7 6.9 9.3e-22 77.5 6.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_4 PF01565.23 EIM91376.1 - 5.8e-18 65.0 0.1 1.1e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM91376.1 - 4e-05 23.6 1.1 7.9e-05 22.7 1.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like GST_N_3 PF13417.6 EIM91378.1 - 3.4e-17 62.6 0.0 6.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIM91378.1 - 6.2e-17 61.7 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM91378.1 - 4.9e-14 52.3 0.0 7.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM91378.1 - 4.4e-12 46.1 0.0 7.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM91378.1 - 1.2e-08 34.9 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM91378.1 - 9.5e-05 22.5 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_3 PF13606.6 EIM91380.1 - 1.1e-05 25.4 0.1 0.15 12.7 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 EIM91380.1 - 0.00018 22.0 0.0 0.17 12.5 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM91380.1 - 0.0015 18.8 0.0 1.5 9.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PPR_2 PF13041.6 EIM91380.1 - 0.029 14.6 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 PPR repeat family Ank_4 PF13637.6 EIM91380.1 - 0.046 14.3 0.0 3.4 8.3 0.0 3.1 2 1 2 4 4 4 0 Ankyrin repeats (many copies) ABC_membrane PF00664.23 EIM91382.1 - 7.9e-65 219.2 23.0 2e-35 122.8 9.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM91382.1 - 1.1e-48 165.3 0.0 8.4e-27 94.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM91382.1 - 2e-08 33.9 3.8 0.025 14.0 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIM91382.1 - 5.1e-07 30.2 0.2 0.074 13.4 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 EIM91382.1 - 2.7e-06 27.4 0.3 0.021 14.6 0.0 3.9 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EIM91382.1 - 2.2e-05 24.5 0.4 0.099 12.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EIM91382.1 - 0.0012 18.6 2.1 0.88 9.4 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EIM91382.1 - 0.0019 18.7 1.7 0.85 10.1 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EIM91382.1 - 0.0026 18.0 0.7 0.56 10.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EIM91382.1 - 0.0032 17.0 0.2 0.91 9.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 EIM91382.1 - 0.0037 17.0 0.1 3.2 7.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 EIM91382.1 - 0.0048 15.9 0.5 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 EIM91382.1 - 0.0081 16.1 0.2 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 EIM91382.1 - 0.0094 15.3 0.6 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 EIM91382.1 - 0.013 15.1 0.1 0.58 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EIM91382.1 - 0.017 15.3 0.2 2.9 8.1 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EIM91382.1 - 0.021 14.4 0.4 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EIM91382.1 - 0.026 14.3 0.6 10 5.8 0.0 3.4 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EIM91382.1 - 0.029 14.4 1.8 2.9 7.9 0.1 2.6 2 0 0 2 2 2 0 Dynamin family TsaE PF02367.17 EIM91382.1 - 0.053 13.5 0.2 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EIM91382.1 - 0.055 13.4 2.3 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 EIM91382.1 - 0.094 12.9 0.6 4.2 7.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 EIM91382.1 - 0.11 12.4 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 EIM91382.1 - 0.15 11.3 0.0 0.36 10.0 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 EIM91382.1 - 0.16 11.0 0.0 18 4.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 EIM91382.1 - 0.16 12.5 0.5 15 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EIM91382.1 - 0.17 10.5 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EIM91382.1 - 0.24 11.1 0.2 1.4 8.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 EIM91382.1 - 3 7.9 5.5 1.2 9.1 0.5 2.5 3 0 0 3 3 2 0 Helicase HerA, central domain MULE PF10551.9 EIM91383.1 - 6.3e-09 36.1 0.0 9.3e-08 32.4 0.0 2.6 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 EIM91383.1 - 0.0002 20.9 0.9 0.00045 19.8 0.9 1.5 1 0 0 1 1 1 1 SWIM zinc finger UPF0061 PF02696.14 EIM91385.1 - 8e-96 321.6 0.0 6.2e-94 315.4 0.0 2.4 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Voldacs PF03517.13 EIM91386.1 - 1.4e-25 90.1 0.0 2.4e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Glyco_trans_1_3 PF13528.6 EIM91391.1 - 5.6e-05 22.6 0.0 8.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 PTPlike_phytase PF14566.6 EIM91392.1 - 1.5e-135 447.5 0.0 2.3e-46 157.8 0.0 3.8 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 EIM91392.1 - 1.8e-05 24.4 0.0 0.062 12.9 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 EIM91392.1 - 0.0046 16.8 0.0 0.18 11.6 0.0 2.9 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EIM91392.1 - 0.026 14.5 0.0 5 7.0 0.0 3.3 4 0 0 4 4 4 0 Tyrosine phosphatase family GMP_synt_C PF00958.22 EIM91393.1 - 2.4e-45 152.5 0.1 4.5e-45 151.6 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EIM91393.1 - 3.2e-35 121.6 0.0 5.7e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EIM91393.1 - 4e-10 39.2 0.1 5.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EIM91393.1 - 7.3e-08 32.4 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 EIM91393.1 - 0.001 18.6 0.0 0.0033 17.0 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EIM91393.1 - 0.0033 16.3 0.1 0.0059 15.4 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 EIM91393.1 - 0.0059 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 EIM91393.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.19 EIM91393.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase Lon_C PF05362.13 EIM91394.1 - 4.4e-70 235.4 0.2 7.1e-70 234.7 0.2 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EIM91394.1 - 2.8e-34 118.8 1.1 3.5e-34 118.5 0.1 1.7 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EIM91394.1 - 2.9e-21 76.3 0.0 1.1e-20 74.4 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIM91394.1 - 1.3e-07 31.6 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EIM91394.1 - 8.4e-07 28.9 0.1 1.7e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EIM91394.1 - 6.8e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 EIM91394.1 - 0.0002 20.4 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 EIM91394.1 - 0.00032 21.1 0.0 0.0012 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EIM91394.1 - 0.00033 20.4 0.0 0.001 18.8 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EIM91394.1 - 0.00061 20.3 0.5 0.0017 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM91394.1 - 0.0012 19.2 0.0 0.017 15.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EIM91394.1 - 0.0059 16.6 0.0 0.025 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EIM91394.1 - 0.008 15.4 0.1 0.1 11.8 0.1 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 EIM91394.1 - 0.013 15.9 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 EIM91394.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 EIM91394.1 - 0.033 14.1 0.2 0.25 11.2 0.0 2.5 2 1 1 3 3 3 0 NTPase SKI PF01202.22 EIM91394.1 - 0.034 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.6 EIM91394.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EIM91394.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EIM91394.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EIM91394.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SPX PF03105.19 EIM91394.1 - 2 8.3 20.5 0.13 12.1 1.1 2.6 2 1 0 2 2 2 0 SPX domain AMP-binding PF00501.28 EIM91396.1 - 1.4e-24 86.5 0.0 3.7e-23 81.8 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 EIM91396.1 - 0.00058 18.8 0.0 0.00099 18.1 0.0 1.3 1 0 0 1 1 1 1 GH3 auxin-responsive promoter MFS_1 PF07690.16 EIM91397.1 - 2.3e-35 122.1 50.8 1e-33 116.7 51.0 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM91397.1 - 7.7e-16 58.0 10.5 7.7e-16 58.0 10.5 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EIM91397.1 - 3.3e-14 52.2 25.7 5.3e-14 51.6 25.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mito_morph_reg PF14972.6 EIM91397.1 - 1.9 8.1 6.3 0.3 10.7 0.9 2.4 3 0 0 3 3 3 0 Mitochondrial morphogenesis regulator Trp_halogenase PF04820.14 EIM91398.1 - 2.4e-33 115.7 0.0 1.9e-19 69.9 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EIM91398.1 - 1.4e-13 50.8 0.0 4.4e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIM91398.1 - 3.8e-07 29.6 0.0 3.9e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM91398.1 - 5.9e-07 29.4 0.1 0.00056 19.6 0.1 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM91398.1 - 2.9e-06 27.4 0.0 1.3e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EIM91398.1 - 8.3e-06 25.4 0.1 6.1e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EIM91398.1 - 5e-05 23.8 0.0 0.043 14.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM91398.1 - 0.00018 20.3 0.0 0.0052 15.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EIM91398.1 - 0.011 15.0 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family DUF4231 PF14015.6 EIM91398.1 - 0.014 15.8 0.4 0.98 9.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) GIDA PF01134.22 EIM91398.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EIM91398.1 - 0.033 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 EIM91398.1 - 0.093 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EIM91398.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EIM91398.1 - 0.12 12.6 0.1 1.3 9.3 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain Pyr_redox_3 PF13738.6 EIM91398.1 - 0.21 10.8 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EIM91399.1 - 1.9e-33 115.9 25.7 4.8e-33 114.5 26.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Flu_M1 PF00598.19 EIM91399.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M1) LapA_dom PF06305.11 EIM91399.1 - 3.1 7.7 5.4 3 7.7 0.1 3.4 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain Methyltransf_25 PF13649.6 EIM91400.1 - 1.3e-11 45.0 0.0 3.5e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM91400.1 - 1.4e-09 37.9 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM91400.1 - 1.9e-09 38.1 0.0 5.8e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM91400.1 - 2.3e-07 30.4 0.0 6.9e-07 28.8 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EIM91400.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91400.1 - 3.4e-05 24.5 0.0 6.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EIM91400.1 - 0.055 13.3 0.0 0.13 12.0 0.0 1.7 1 1 0 2 2 2 0 Hypothetical methyltransferase TPMT PF05724.11 EIM91400.1 - 0.063 12.9 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MFS_1 PF07690.16 EIM91401.1 - 1.4e-33 116.3 26.2 2.5e-33 115.5 25.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily CBM_5_12 PF02839.14 EIM91403.1 - 0.06 14.0 7.3 0.06 14.0 7.3 3.2 3 0 0 3 3 3 0 Carbohydrate binding domain Forkhead PF00250.18 EIM91404.1 - 9.1e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain XRN1_D1 PF18332.1 EIM91405.1 - 6.4e-49 166.3 0.5 1.5e-48 165.1 0.1 1.8 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EIM91405.1 - 3e-30 104.3 0.1 5.8e-30 103.4 0.1 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EIM91405.1 - 4.8e-23 81.0 0.3 1.1e-22 79.9 0.3 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EIM91405.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Plasmid_parti PF01672.16 EIM91405.1 - 0.17 12.5 0.1 0.35 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative plasmid partition protein TauD PF02668.16 EIM91406.1 - 6.1e-61 206.6 0.3 7.8e-61 206.2 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATA PF00320.27 EIM91407.1 - 3.3e-15 55.4 3.8 6.6e-15 54.4 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger PX PF00787.24 EIM91408.1 - 0.16 12.0 0.8 0.84 9.6 0.3 2.4 2 1 0 2 2 2 0 PX domain Erg28 PF03694.13 EIM91409.1 - 2.1e-39 134.3 4.8 2.7e-39 133.9 4.8 1.1 1 0 0 1 1 1 1 Erg28 like protein NACHT PF05729.12 EIM91411.1 - 8.3e-10 38.8 0.0 2.5e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EIM91411.1 - 0.057 14.0 0.0 1.1 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EIM91411.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.32 EIM91412.1 - 9.1e-44 146.6 33.4 1e-08 35.7 0.2 10.3 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM91412.1 - 3.2e-23 81.8 0.0 0.0055 17.0 0.0 7.7 3 3 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM91412.1 - 1.9e-12 46.8 2.3 0.00087 18.3 0.1 5.7 2 2 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIM91412.1 - 8e-11 41.6 9.7 0.031 14.2 1.0 8.6 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EIM91412.1 - 1.9e-07 31.2 0.0 2.5 7.9 0.0 4.8 2 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 EIM91412.1 - 7.2e-06 25.0 0.3 0.75 8.5 0.0 4.4 3 2 1 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.8 EIM91412.1 - 8.6e-06 24.7 2.1 1.6 7.2 0.3 4.5 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 EIM91412.1 - 0.0001 21.7 1.9 0.32 10.3 0.0 4.4 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EIM91412.1 - 0.00066 18.5 3.7 2.4 6.8 0.6 4.5 2 2 3 5 5 5 3 Nup133 N terminal like PQQ_2 PF13360.6 EIM91412.1 - 0.048 13.2 0.1 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Imm64 PF15600.6 EIM91412.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 64 Na_Ca_ex PF01699.24 EIM91413.1 - 1.7e-40 138.4 38.5 1.2e-20 74.0 16.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MSA-2c PF12238.8 EIM91413.1 - 4 7.4 5.5 7.3 6.5 5.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c ADH_zinc_N_2 PF13602.6 EIM91414.1 - 1.9e-21 77.5 0.0 4e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EIM91414.1 - 3.8e-20 72.2 0.0 5.7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91414.1 - 1.6e-12 47.3 0.1 1.1e-11 44.6 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EIM91415.1 - 3.4e-85 284.4 22.9 8.8e-44 149.3 4.7 2.9 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM91415.1 - 2.8e-68 230.0 18.6 2.2e-34 119.0 2.8 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EIM91415.1 - 1.4e-32 111.9 0.0 2.9e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EIM91415.1 - 2.6e-28 99.1 11.9 1.7e-15 57.4 2.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 EIM91415.1 - 1.8e-05 24.9 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.18 EIM91415.1 - 0.011 15.6 10.4 0.072 13.0 1.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phage_portal_2 PF05136.13 EIM91415.1 - 0.014 14.6 0.0 2.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Phage portal protein, lambda family THF_DHG_CYH_C PF02882.19 EIM91415.1 - 0.023 14.0 0.4 2.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CstA_5TM PF13722.6 EIM91415.1 - 0.91 9.9 5.5 6.9 7.1 0.0 3.1 3 1 0 3 3 3 0 5TM C-terminal transporter carbon starvation CstA DUF543 PF04418.12 EIM91415.1 - 1.3 9.1 6.8 6.9 6.7 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) PglL_A PF15864.5 EIM91415.1 - 3.9 7.3 8.3 11 5.8 1.1 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase PAS_3 PF08447.12 EIM91416.1 - 6e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EIM91416.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EIM91416.1 - 0.00049 20.3 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 EIM91416.1 - 0.14 12.3 0.0 0.56 10.3 0.0 1.8 2 0 0 2 2 2 0 PAS domain Ank_2 PF12796.7 EIM91417.1 - 5.4e-37 126.2 4.7 4e-11 43.3 0.1 4.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM91417.1 - 1.4e-22 79.7 4.5 4.6e-07 30.3 0.2 6.9 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM91417.1 - 1.5e-19 68.0 5.4 0.0059 17.0 0.1 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EIM91417.1 - 7e-17 61.0 12.4 0.02 15.3 0.1 7.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EIM91417.1 - 2.6e-11 43.5 7.1 6.5e-06 26.3 0.2 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) DUF1748 PF08520.10 EIM91418.1 - 6.9e-27 93.2 0.0 7.6e-27 93.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Rad51 PF08423.11 EIM91419.1 - 4.6e-15 55.6 0.0 8.9e-14 51.4 0.0 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EIM91419.1 - 7.8e-07 28.9 0.1 1.8e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 EIM91419.1 - 5.7e-05 22.7 0.2 0.0001 21.9 0.2 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 EIM91419.1 - 0.00039 20.2 0.0 0.00076 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIM91419.1 - 0.00092 19.5 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EIM91419.1 - 0.0021 17.5 0.7 0.01 15.2 0.7 2.2 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.6 EIM91419.1 - 0.0034 17.8 0.1 0.0063 16.9 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain PAXNEB PF05625.11 EIM91419.1 - 0.0038 16.4 0.7 0.28 10.3 0.0 2.7 3 0 0 3 3 3 1 PAXNEB protein DUF2075 PF09848.9 EIM91419.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EIM91419.1 - 0.033 14.2 0.1 0.053 13.6 0.2 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EIM91419.1 - 0.13 11.8 0.2 0.98 9.0 0.2 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EIM91419.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EIM91419.1 - 0.16 11.2 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 EIM91419.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Elong_Iki1 PF10483.9 EIM91419.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 Med22 PF06179.12 EIM91420.1 - 5.8e-17 61.8 4.7 7.6e-17 61.4 4.7 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex MIR PF02815.19 EIM91420.1 - 0.035 14.0 0.1 0.042 13.7 0.1 1.1 1 0 0 1 1 1 0 MIR domain SCP2 PF02036.17 EIM91421.1 - 5.8e-25 87.7 1.6 7.2e-25 87.4 1.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EIM91421.1 - 9.6e-06 25.9 0.6 1.2e-05 25.5 0.6 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Big_6 PF17936.1 EIM91421.1 - 0.017 15.4 1.0 0.94 9.8 0.1 2.2 1 1 1 2 2 2 0 Bacterial Ig domain TLP1_add_C PF18313.1 EIM91421.1 - 0.1 12.6 0.0 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain Dynamin_N PF00350.23 EIM91422.1 - 8.7e-42 143.0 0.0 1.9e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EIM91422.1 - 4.9e-08 32.5 0.0 2.1e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EIM91422.1 - 4.3e-05 23.6 0.0 0.00018 21.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EIM91422.1 - 0.034 13.9 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM91422.1 - 0.063 13.0 0.5 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RecG_N PF17190.4 EIM91422.1 - 1.7 9.4 10.6 0.72 10.6 2.1 3.3 3 0 0 3 3 3 0 RecG N-terminal helical domain DAO PF01266.24 EIM91423.1 - 4.5e-26 92.3 0.0 6e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIM91423.1 - 1.9e-05 24.0 0.0 3.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM91423.1 - 9e-05 22.6 0.2 0.00022 21.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EIM91423.1 - 0.00012 22.5 0.0 0.00024 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EIM91423.1 - 0.00043 19.6 0.1 0.00069 19.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EIM91423.1 - 0.0025 18.3 0.2 0.0072 16.9 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIM91423.1 - 0.015 14.4 0.3 0.021 13.9 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EIM91423.1 - 0.026 13.8 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EIM91423.1 - 0.058 12.5 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EIM91423.1 - 0.11 11.1 0.1 0.26 9.9 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein DHDPS PF00701.22 EIM91424.1 - 6.8e-29 100.5 0.0 3.3e-28 98.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Serinc PF03348.15 EIM91425.1 - 1.7e-161 538.0 14.9 1.9e-161 537.8 14.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) T2SSF PF00482.23 EIM91425.1 - 0.072 13.1 1.2 5.3 7.0 0.0 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Glyco_hydro81C PF17652.1 EIM91426.1 - 5.7e-74 249.4 5.2 9.4e-74 248.7 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EIM91426.1 - 1.8e-30 106.2 9.0 3.7e-30 105.2 9.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 EIM91426.1 - 6.6e-05 23.1 0.0 0.003 17.8 0.0 2.5 1 1 0 1 1 1 1 Fascin domain CarbopepD_reg_2 PF13715.6 EIM91426.1 - 0.26 11.3 3.9 1 9.4 0.1 3.0 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Vps39_1 PF10366.9 EIM91427.1 - 3.7e-29 101.2 0.1 2.2e-28 98.7 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EIM91427.1 - 2.1e-23 82.8 0.1 5.9e-23 81.4 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EIM91427.1 - 1.1e-19 71.1 0.0 3.5e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 EIM91427.1 - 2.1e-12 47.1 2.5 4.5e-07 29.8 0.4 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS Ank_2 PF12796.7 EIM91428.1 - 1e-21 77.3 0.0 1.4e-08 35.2 0.0 4.8 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM91428.1 - 1.9e-21 75.8 5.1 3e-06 27.4 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIM91428.1 - 3.1e-16 59.5 2.3 0.00025 21.5 0.0 6.4 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EIM91428.1 - 2.7e-15 56.0 1.0 0.0049 17.3 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EIM91428.1 - 5.3e-15 54.0 0.1 0.0018 18.6 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat RNAse_A_bac PF18431.1 EIM91428.1 - 0.037 15.0 0.4 0.21 12.6 1.0 1.9 2 0 0 2 2 2 0 Bacterial CdiA-CT RNAse A domain DUF1843 PF08898.10 EIM91428.1 - 0.1 13.1 0.7 2.6 8.6 0.5 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) ABC_membrane PF00664.23 EIM91429.1 - 5.4e-70 236.2 27.7 6.9e-38 130.9 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM91429.1 - 2.2e-50 170.8 0.0 8.5e-29 100.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM91429.1 - 2.1e-07 30.6 2.4 0.0078 15.7 0.1 3.5 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIM91429.1 - 0.0001 22.7 0.6 0.54 10.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EIM91429.1 - 0.0001 22.3 3.1 0.043 13.9 0.3 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EIM91429.1 - 0.0015 18.4 2.9 1.9 8.2 0.6 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM91429.1 - 0.0018 18.0 2.5 0.29 10.9 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EIM91429.1 - 0.0027 17.6 0.5 1.8 8.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 EIM91429.1 - 0.0037 17.5 1.2 1.1 9.5 0.1 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 EIM91429.1 - 0.0041 16.8 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EIM91429.1 - 0.008 15.7 1.7 2 7.9 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 EIM91429.1 - 0.013 14.8 0.6 0.79 9.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EIM91429.1 - 0.02 14.5 0.1 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EIM91429.1 - 0.033 14.5 3.7 7.7 6.8 0.2 3.3 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EIM91429.1 - 0.034 14.2 3.9 0.6 10.1 0.2 2.6 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 EIM91429.1 - 0.053 14.0 5.4 0.37 11.3 0.2 2.7 3 0 0 3 3 2 0 AAA domain MobB PF03205.14 EIM91429.1 - 0.058 13.3 2.2 0.22 11.4 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 EIM91429.1 - 0.066 12.1 5.2 0.27 10.1 0.4 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EIM91429.1 - 0.071 13.1 1.8 0.5 10.4 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EIM91429.1 - 0.084 12.6 5.0 3.9 7.1 0.2 2.8 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 EIM91429.1 - 0.1 12.3 4.3 11 5.7 0.4 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EIM91429.1 - 0.11 11.6 1.5 5.7 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 EIM91429.1 - 0.13 11.6 1.3 3.4 6.9 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 EIM91429.1 - 0.14 11.9 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EIM91429.1 - 0.16 11.9 2.7 0.25 11.2 0.4 2.2 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 EIM91429.1 - 0.26 11.4 6.0 0.4 10.7 0.6 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 EIM91429.1 - 0.41 10.2 3.7 0.41 10.2 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EIM91429.1 - 0.42 11.2 2.7 10 6.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EIM91429.1 - 0.64 10.2 3.9 20 5.3 0.3 3.1 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 EIM91430.1 - 2.7e-38 131.5 0.0 1.2e-37 129.3 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM91430.1 - 7.1e-22 77.9 0.2 7e-19 68.2 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EIM91430.1 - 1.4e-09 38.2 0.0 4.5e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIM91430.1 - 0.014 15.7 0.1 0.043 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 EIM91430.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 EIM91430.1 - 0.22 11.8 3.2 2.9 8.1 0.0 3.0 3 1 0 3 3 3 0 AAA domain MAP65_ASE1 PF03999.12 EIM91430.1 - 1.6 7.3 6.6 2.4 6.7 6.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Piwi PF02171.17 EIM91431.1 - 2.4e-86 289.7 0.0 3.2e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EIM91431.1 - 3.5e-18 65.0 0.1 1.1e-17 63.5 0.1 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EIM91431.1 - 3.3e-16 60.2 0.0 7.3e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 EIM91431.1 - 2.9e-14 53.1 0.0 7.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EIM91431.1 - 7.5e-14 51.8 0.0 2.2e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EIM91431.1 - 7.3e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Asp PF00026.23 EIM91432.1 - 3e-22 79.5 1.2 1.1e-20 74.3 1.2 2.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease CNDH2_M PF16869.5 EIM91432.1 - 0.0087 16.8 0.7 0.019 15.6 0.7 1.5 1 0 0 1 1 1 1 PF16858 Asp_protease_2 PF13650.6 EIM91432.1 - 0.011 16.3 0.1 0.14 12.9 0.1 2.8 3 0 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 EIM91432.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal p450 PF00067.22 EIM91435.1 - 6.8e-64 216.3 0.0 5.8e-63 213.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM91436.1 - 8.7e-58 196.2 0.0 1.3e-56 192.3 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.20 EIM91437.1 - 7.1e-16 58.9 0.1 1.7e-15 57.6 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family WD40 PF00400.32 EIM91438.1 - 1.4e-16 60.6 4.3 0.0013 19.5 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EIM91438.1 - 0.065 11.9 0.2 0.21 10.2 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 eIF3_subunit PF08597.10 EIM91439.1 - 3.8e-64 216.9 14.7 4.3e-64 216.7 14.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4962 PF16332.5 EIM91439.1 - 0.14 10.6 0.1 0.2 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) VIR_N PF15912.5 EIM91439.1 - 2.7 7.5 11.1 0.72 9.4 8.1 1.6 2 0 0 2 2 2 0 Virilizer, N-terminal Asp PF00026.23 EIM91440.1 - 8.2e-25 87.9 2.7 1.4e-23 83.8 2.7 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EIM91440.1 - 0.0002 22.0 0.2 0.028 15.1 0.1 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EIM91440.1 - 0.0046 17.5 0.0 2 9.0 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Coa1 PF08695.10 EIM91440.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Glyco_hydro_11 PF00457.17 EIM91441.1 - 2.8e-77 258.3 16.6 3.6e-77 258.0 16.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 EIM91441.1 - 5.3e-12 45.5 9.6 2e-11 43.7 9.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EIM91441.1 - 0.89 9.9 8.9 2.1 8.6 8.9 1.7 1 1 0 1 1 1 0 Toxin 7 STAT_alpha PF01017.20 EIM91442.1 - 0.0014 18.5 0.2 0.0027 17.7 0.2 1.3 1 0 0 1 1 1 1 STAT protein, all-alpha domain FliJ PF02050.16 EIM91442.1 - 0.0038 17.4 3.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 2 Flagellar FliJ protein ANAPC4_WD40 PF12894.7 EIM91442.1 - 0.076 13.3 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain NBP1 PF08537.10 EIM91442.1 - 0.08 12.4 7.7 0.14 11.5 7.7 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 F-box-like PF12937.7 EIM91445.1 - 3e-06 27.0 0.6 9.3e-06 25.5 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91445.1 - 5.6 7.0 8.1 11 6.0 1.3 2.9 3 0 0 3 3 3 0 F-box domain DUF4361 PF14274.6 EIM91446.1 - 0.004 17.4 0.1 0.006 16.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4361) TAP_C PF03943.13 EIM91448.1 - 1.5e-13 50.1 0.1 4.4e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.6 EIM91448.1 - 0.0014 18.2 0.3 0.0024 17.4 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EIM91448.1 - 2 9.0 7.6 0.65 10.5 3.7 2.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF5336 PF17270.2 EIM91449.1 - 6.5 6.4 8.0 13 5.3 8.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5336) COesterase PF00135.28 EIM91451.1 - 1.2e-82 278.5 0.0 8.1e-82 275.7 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM91451.1 - 0.04 13.8 0.2 0.093 12.6 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EIM91452.1 - 4.7e-91 306.2 0.0 5.8e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM91452.1 - 0.0017 18.2 0.3 0.0045 16.9 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 EIM91454.1 - 8.9e-45 153.8 0.0 2.4e-44 152.4 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase COesterase PF00135.28 EIM91455.1 - 1.3e-87 294.8 0.0 1.6e-87 294.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIM91455.1 - 5.6e-06 26.4 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DIOX_N PF14226.6 EIM91456.1 - 9.2e-11 42.5 0.1 5e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM91456.1 - 1.6e-06 28.5 0.0 5.1e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIM91457.1 - 3.6e-16 60.0 0.1 2.6e-15 57.2 0.0 2.4 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM91457.1 - 2.2e-14 53.7 0.0 4.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPA PF08616.10 EIM91458.1 - 1.2e-05 25.2 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 EIM91458.1 - 0.002 18.1 4.1 0.018 15.0 0.7 3.2 2 1 0 2 2 2 1 DENN (AEX-3) domain SPX PF03105.19 EIM91458.1 - 0.28 11.1 18.6 0.54 10.1 13.5 2.1 2 0 0 2 2 2 0 SPX domain PI3K_1B_p101 PF10486.9 EIM91458.1 - 3.5 5.3 10.1 5.1 4.7 10.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Frag1 PF10277.9 EIM91459.1 - 2.6e-40 138.3 8.3 3.1e-40 138.0 8.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SUR7 PF06687.12 EIM91459.1 - 0.42 10.2 5.0 4.5 6.8 0.3 2.5 2 1 0 2 2 2 0 SUR7/PalI family DUF4199 PF13858.6 EIM91459.1 - 2.3 8.6 14.5 2.5 8.5 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) PEN-2 PF10251.9 EIM91459.1 - 3.1 8.3 7.6 1.3 9.5 0.4 2.6 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Glyco_hydro_43 PF04616.14 EIM91460.1 - 2.1e-17 63.4 4.6 3.6e-17 62.6 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 EIM91460.1 - 0.0021 18.3 4.5 0.0021 18.3 4.5 2.0 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) dCMP_cyt_deam_1 PF00383.23 EIM91461.1 - 8.8e-13 48.0 0.2 2e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIM91461.1 - 2.1e-07 30.8 0.2 9.2e-07 28.7 0.2 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Abhydrolase_7 PF12715.7 EIM91461.1 - 0.0074 15.6 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase family GSIII_N PF12437.8 EIM91461.1 - 0.077 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal Glyco_hydro_10 PF00331.20 EIM91462.1 - 1.2e-94 317.1 0.0 1.7e-94 316.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EIM91462.1 - 6e-13 48.5 15.0 6e-13 48.5 15.0 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Cellulase PF00150.18 EIM91462.1 - 0.048 13.1 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) RhoGAP PF00620.27 EIM91464.1 - 5.1e-37 127.0 0.0 7e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 EIM91464.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Glyco_hydro_17 PF00332.18 EIM91465.1 - 3.5e-12 46.5 2.8 3.2e-10 40.1 1.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 ArgoL1 PF08699.10 EIM91465.1 - 0.068 12.8 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Argonaute linker 1 domain RhoGAP PF00620.27 EIM91466.1 - 3e-09 36.9 0.0 5.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PXB PF12828.7 EIM91466.1 - 0.19 11.7 0.2 0.36 10.8 0.2 1.4 1 0 0 1 1 1 0 PX-associated DEAD PF00270.29 EIM91469.1 - 3.2e-34 118.2 0.6 5.4e-34 117.5 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM91469.1 - 1.7e-28 99.2 0.2 5.1e-28 97.6 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EIM91469.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EIM91469.1 - 0.56 10.5 2.0 3.6 7.9 0.8 2.7 2 1 0 2 2 2 0 AAA domain ketoacyl-synt PF00109.26 EIM91472.1 - 1.4e-74 250.8 0.1 1.4e-59 201.7 0.0 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EIM91472.1 - 3.3e-42 145.1 0.0 7.4e-38 130.8 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EIM91472.1 - 2.8e-35 120.9 0.1 5.6e-35 119.9 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 EIM91472.1 - 1.4e-23 83.9 4.6 2e-21 76.8 0.1 3.2 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 EIM91472.1 - 6.2e-18 65.1 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 EIM91472.1 - 6.1e-16 58.5 3.2 1.3e-07 31.8 0.5 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 EIM91472.1 - 2.6e-08 34.3 0.0 3.7e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 Thioesterase domain KAsynt_C_assoc PF16197.5 EIM91472.1 - 7.9e-08 32.8 0.0 2.2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EIM91472.1 - 5.5e-07 30.4 0.2 0.0024 18.5 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.23 EIM91472.1 - 0.00095 18.6 0.6 0.002 17.6 0.6 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glyco_hydro_10 PF00331.20 EIM91473.1 - 1.3e-97 326.7 0.0 1.6e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EIM91473.1 - 7e-12 45.1 11.8 7e-12 45.1 11.8 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Cellulase PF00150.18 EIM91473.1 - 0.07 12.5 0.1 0.24 10.8 0.1 1.8 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) COQ9 PF08511.11 EIM91476.1 - 4.8e-10 39.1 0.1 7.8e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 COQ9 PRP4 PF08799.11 EIM91476.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GFA PF04828.14 EIM91477.1 - 2.7e-21 75.7 0.3 3.5e-21 75.3 0.3 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 EIM91477.1 - 0.078 12.9 0.0 0.078 12.9 0.0 2.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 EIM91477.1 - 0.16 11.6 0.7 0.16 11.6 0.7 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 EIM91477.1 - 5.9 6.9 8.5 0.59 10.1 0.4 2.7 3 0 0 3 3 3 0 Nudix N-terminal Peptidase_M20 PF01546.28 EIM91478.1 - 2.2e-26 92.8 0.0 5e-26 91.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIM91478.1 - 2.9e-15 56.1 0.0 5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIM91478.1 - 0.0098 15.6 0.0 0.042 13.5 0.0 2.0 2 1 0 2 2 2 1 Peptidase family M28 LRR_4 PF12799.7 EIM91479.1 - 0.00086 19.7 0.2 0.38 11.2 0.3 3.2 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) Kelch_4 PF13418.6 EIM91481.1 - 2e-20 72.5 9.7 8.2e-07 28.9 0.1 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EIM91481.1 - 1.2e-15 56.8 6.4 5.3e-05 23.0 0.0 6.2 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EIM91481.1 - 1.6e-15 56.7 11.6 0.00037 20.4 0.0 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EIM91481.1 - 6.7e-14 51.2 1.0 0.0036 16.9 0.0 5.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EIM91481.1 - 4.8e-13 48.9 13.3 0.0025 18.0 0.1 5.8 4 1 2 6 6 6 4 Kelch motif Glyoxal_oxid_N PF07250.11 EIM91481.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Tannase PF07519.11 EIM91482.1 - 7.8e-93 311.9 1.0 1e-92 311.6 1.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase APH PF01636.23 EIM91484.1 - 1.6e-12 47.9 0.0 2.3e-12 47.4 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EIM91484.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.23 EIM91485.1 - 4.2e-14 53.1 0.0 5.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EIM91485.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain EcKinase PF02958.20 EIM91485.1 - 0.079 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EIM91485.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Importin_rep_5 PF18816.1 EIM91485.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Importin repeat Alpha_kinase PF02816.18 EIM91487.1 - 0.0097 16.0 0.0 0.056 13.6 0.0 2.1 1 1 0 1 1 1 1 Alpha-kinase family zf-CpG_bind_C PF12269.8 EIM91487.1 - 2.4 7.9 5.8 4.9 6.9 5.8 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Plavaka PF18759.1 EIM91488.1 - 2.2e-115 385.3 0.0 2.9e-115 384.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Fungal_trans_2 PF11951.8 EIM91489.1 - 4.5e-35 121.2 0.0 3.7e-21 75.4 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM91489.1 - 0.00079 19.5 9.3 0.0013 18.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.29 EIM91490.1 - 1.3e-33 115.6 1.9 3.8e-19 69.1 0.2 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 EIM91490.1 - 4.8e-15 55.9 11.3 1.5e-07 31.8 5.6 4.2 3 1 0 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.6 EIM91490.1 - 1.5e-08 34.8 1.8 6.4e-06 26.4 0.3 2.7 3 0 0 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 EIM91490.1 - 6.3e-05 22.8 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 EIM91490.1 - 0.0011 19.3 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_9 PF15410.6 EIM91490.1 - 0.015 15.7 0.6 2.6 8.4 0.4 3.5 3 1 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 EIM91490.1 - 0.016 15.4 1.0 1 9.5 0.0 2.6 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology ACBP PF00887.19 EIM91491.1 - 3.3e-30 104.1 0.4 4.3e-30 103.8 0.4 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein DUF202 PF02656.15 EIM91492.1 - 1.2e-13 51.2 1.7 6.8e-13 48.9 0.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Bac_rhodopsin PF01036.18 EIM91492.1 - 0.014 15.0 0.9 0.017 14.7 0.9 1.1 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein PEX11 PF05648.14 EIM91493.1 - 4.8e-10 39.3 0.3 1.5e-06 27.9 0.0 2.5 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) LEAP-2 PF07359.11 EIM91494.1 - 0.19 11.6 8.8 1.1 9.1 0.7 3.3 3 0 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Colipase-like PF15083.6 EIM91494.1 - 1.2 9.3 14.1 1.5 9.0 3.5 3.4 1 1 3 4 4 4 0 Colipase-like DEAD PF00270.29 EIM91495.1 - 4.6e-12 46.1 0.1 5.7e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM91495.1 - 3.1e-06 27.3 0.0 3.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mannitol_dh_C PF08125.13 EIM91496.1 - 8.5e-19 68.0 0.0 9.8e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Helicase_C PF00271.31 EIM91497.1 - 3.4e-09 37.0 0.0 6.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fungal_trans_2 PF11951.8 EIM91499.1 - 3.6e-37 128.1 0.4 5e-37 127.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM91499.1 - 1.7e-05 24.8 8.6 2.8e-05 24.2 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Drf_GBD PF06371.13 EIM91500.1 - 3.6e-13 49.5 0.2 3.6e-09 36.4 0.1 2.5 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain zf-C2H2 PF00096.26 EIM91502.1 - 1.6e-12 47.1 15.3 0.00051 20.4 0.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM91502.1 - 7.2e-08 32.6 14.8 0.039 14.8 0.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIM91502.1 - 1.7e-07 31.4 19.2 4.3e-05 23.7 0.4 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EIM91502.1 - 8.8e-06 25.6 6.4 0.018 15.0 0.5 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EIM91502.1 - 0.00055 20.2 3.3 0.0034 17.7 3.1 1.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 EIM91502.1 - 0.0086 16.7 11.0 0.23 12.1 6.2 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EIM91502.1 - 0.048 13.8 5.4 2.1 8.5 0.1 2.7 1 1 2 3 3 3 0 Aberrant zinc-finger Zn-ribbon_8 PF09723.10 EIM91502.1 - 0.37 10.9 7.2 7.6 6.8 0.5 2.8 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 EIM91502.1 - 0.48 10.2 5.6 12 5.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 EIM91502.1 - 1 9.9 9.3 4.4 7.8 0.0 3.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF3098 PF11297.8 EIM91503.1 - 0.039 13.6 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DnaJ_C PF01556.18 EIM91504.1 - 9.3e-40 136.1 0.3 1.3e-39 135.7 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIM91504.1 - 1.5e-27 95.5 1.8 2.1e-27 95.0 1.8 1.2 1 0 0 1 1 1 1 DnaJ domain DUF1729 PF08354.10 EIM91508.1 - 1.1e-149 498.2 0.0 1.7e-149 497.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 EIM91508.1 - 3e-73 245.8 0.4 6e-73 244.8 0.4 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EIM91508.1 - 4.8e-71 238.4 0.0 2.2e-70 236.2 0.0 2.3 3 0 0 3 3 2 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 EIM91508.1 - 4.1e-68 230.2 0.0 1.5e-67 228.3 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 EIM91508.1 - 6.4e-42 142.8 0.0 1.6e-41 141.6 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 EIM91508.1 - 2.2e-28 98.3 0.0 7.1e-28 96.6 0.0 1.9 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EIM91508.1 - 2.2e-28 99.6 0.1 7.3e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EIM91508.1 - 4.6e-26 91.9 0.1 9.4e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_N PF17828.1 EIM91508.1 - 1.5e-22 80.0 0.3 4e-22 78.6 0.3 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Ketoacyl-synt_C PF02801.22 EIM91508.1 - 2.8e-16 59.6 0.1 7.1e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 EIM91508.1 - 1.4e-13 51.0 0.0 3.6e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 EIM91508.1 - 4.3e-11 43.1 0.3 8.4e-10 38.9 0.1 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 EIM91508.1 - 5e-07 29.4 0.0 3.7e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EIM91508.1 - 0.11 12.4 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 KR domain DUF3597 PF12200.8 EIM91508.1 - 1.8 9.1 6.4 0.37 11.3 1.4 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF3597) CTP_transf_like PF01467.26 EIM91509.1 - 0.0012 19.0 0.0 0.0075 16.5 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like Sugar_tr PF00083.24 EIM91510.1 - 7.9e-111 371.1 24.3 9e-111 370.9 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM91510.1 - 3e-29 102.1 65.0 5.7e-27 94.6 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIM91510.1 - 0.02 13.3 5.5 0.0093 14.4 1.9 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Patatin PF01734.22 EIM91511.1 - 7.8e-23 81.7 0.0 1.4e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase VSP PF03302.13 EIM91512.1 - 0.00047 19.1 20.1 0.00068 18.6 20.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein CDK5_activator PF03261.15 EIM91512.1 - 0.089 12.3 12.7 0.12 11.9 12.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein FtsK_4TM PF13491.6 EIM91512.1 - 0.096 12.4 0.7 0.23 11.1 0.6 1.6 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE LAP1C PF05609.12 EIM91512.1 - 0.13 11.4 15.0 0.17 11.0 15.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4407 PF14362.6 EIM91512.1 - 1.6 8.0 11.0 2.3 7.5 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SWI-SNF_Ssr4 PF08549.10 EIM91512.1 - 3.3 6.2 26.0 4.5 5.8 26.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Tim54 PF11711.8 EIM91512.1 - 4.1 6.1 10.7 6.8 5.4 10.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1387 PF07139.11 EIM91512.1 - 9.9 5.8 19.4 18 5.0 19.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) VTC PF09359.10 EIM91513.1 - 2.9e-96 322.1 0.0 2.9e-96 322.1 0.0 2.0 3 0 0 3 3 3 1 VTC domain SPX PF03105.19 EIM91513.1 - 1.9e-14 54.4 43.8 6.3e-08 32.9 1.0 4.7 3 2 1 4 4 4 3 SPX domain DUF202 PF02656.15 EIM91513.1 - 1.5e-10 41.4 1.4 3.3e-10 40.3 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Gtr1_RagA PF04670.12 EIM91514.1 - 1e-43 149.4 0.0 1.6e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EIM91514.1 - 0.00025 21.3 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EIM91514.1 - 0.0035 17.4 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EIM91514.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 EIM91514.1 - 0.053 13.1 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_14 PF13173.6 EIM91514.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EIM91514.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.9 EIM91514.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EIM91514.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LRR_6 PF13516.6 EIM91515.1 - 1.5e-09 37.1 9.4 0.8 9.9 0.0 6.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 EIM91515.1 - 7.7e-08 32.5 13.6 0.12 12.8 0.3 5.8 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIM91515.1 - 0.0024 18.2 7.1 20 6.2 0.0 5.9 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EIM91515.1 - 1.3 8.9 18.3 13 5.7 0.1 6.5 5 2 1 6 6 6 0 Leucine rich repeat PrpF PF04303.13 EIM91516.1 - 1.6e-65 221.5 7.6 1.3e-28 100.0 1.6 4.5 3 1 0 3 3 3 3 PrpF protein CDC27 PF09507.10 EIM91518.1 - 1.1e-41 143.7 85.0 8e-29 101.3 32.4 3.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 XhlA PF10779.9 EIM91521.1 - 3.6 7.9 5.4 0.44 10.8 0.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF4218 PF13960.6 EIM91522.1 - 0.019 14.6 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF1491 PF07372.12 EIM91522.1 - 0.13 12.7 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) COE1_DBD PF16422.5 EIM91525.1 - 0.22 10.9 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain ECH_1 PF00378.20 EIM91526.1 - 2.5e-41 141.6 0.0 3.1e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIM91526.1 - 5e-16 59.1 0.0 3.4e-15 56.4 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Cytochrom_B561 PF03188.16 EIM91527.1 - 1.6e-06 28.3 6.6 4.1e-06 27.0 6.7 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EIM91527.1 - 0.0084 15.9 3.1 0.0084 15.9 3.1 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) Ferric_reduct PF01794.19 EIM91527.1 - 0.19 11.9 12.2 2.9 8.0 7.0 2.5 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF420 PF04238.12 EIM91527.1 - 0.67 10.2 7.8 0.17 12.1 0.7 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF420) DUF3021 PF11457.8 EIM91527.1 - 8.9 6.7 9.0 17 5.8 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Cyt-b5 PF00173.28 EIM91528.1 - 2.4e-18 66.0 0.0 3.3e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RAI1 PF08652.11 EIM91529.1 - 1.8e-20 72.9 0.1 6.7e-20 71.1 0.1 2.0 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease RMI1_C PF16099.5 EIM91529.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold TFIIA PF03153.13 EIM91530.1 - 3.6 7.5 23.2 6.3 6.7 23.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.11 EIM91531.1 - 0.013 14.1 0.2 0.037 12.5 0.0 1.8 2 1 0 2 2 2 0 Peptidase family S64 Whi5 PF08528.11 EIM91533.1 - 0.00037 20.0 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 Whi5 like TMEM171 PF15471.6 EIM91533.1 - 1.3 8.0 4.8 3.7 6.4 4.8 1.7 1 0 0 1 1 1 0 Transmembrane protein family 171 SWIRM-assoc_2 PF16496.5 EIM91533.1 - 9.2 5.0 8.6 17 4.1 8.6 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Lysine_decarbox PF03641.14 EIM91535.1 - 7.6e-34 116.7 0.6 9.9e-34 116.3 0.6 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EIM91535.1 - 4.6e-07 29.5 2.8 7.2e-07 28.9 2.8 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Abhydrolase_3 PF07859.13 EIM91536.1 - 9.6e-17 61.5 0.0 1.3e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM91536.1 - 1.9e-11 43.5 0.0 2e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 EIM91536.1 - 0.084 12.7 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.22 EIM91537.1 - 4.9e-38 131.1 0.0 5.9e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3025 PF11227.8 EIM91537.1 - 0.096 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) MEA1 PF06910.11 EIM91537.1 - 0.13 12.9 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) Acyl-CoA_dh_M PF02770.19 EIM91538.1 - 0.0031 17.7 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain XPG_I PF00867.18 EIM91541.1 - 2.1e-17 63.2 0.0 3.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EIM91541.1 - 6.1e-08 33.1 0.0 1.8e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain GEN1_C PF18380.1 EIM91541.1 - 0.0038 18.1 0.1 0.043 14.7 0.1 2.2 1 1 1 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain Phage_integrase PF00589.22 EIM91542.1 - 0.00089 19.1 0.0 0.0031 17.3 0.0 1.8 1 1 0 1 1 1 1 Phage integrase family SAP PF02037.27 EIM91543.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 SAP domain ORC6 PF05460.13 EIM91543.1 - 2.2 7.5 9.3 0.023 14.0 0.7 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) MliC PF09864.9 EIM91545.1 - 0.0036 17.2 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme Herpes_UL4 PF03277.13 EIM91545.1 - 0.097 12.3 0.0 0.12 12.0 0.0 1.2 1 1 0 1 1 1 0 Herpesvirus UL4 family adh_short PF00106.25 EIM91546.1 - 7e-41 139.8 0.1 9.4e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM91546.1 - 8.9e-29 100.7 0.0 1.1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM91546.1 - 6.1e-06 26.3 0.6 1.3e-05 25.2 0.6 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM91546.1 - 1.2e-05 24.8 0.0 9.9e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EIM91546.1 - 0.002 18.0 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Meth_synt_2 PF01717.18 EIM91548.1 - 9e-15 54.7 0.0 8e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIM91548.1 - 5.7e-06 26.1 0.0 0.0045 16.6 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Oxidored_q2 PF00420.24 EIM91549.1 - 7.7 6.2 9.8 4.1 7.1 2.7 2.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2415 PF10313.9 EIM91550.1 - 5.8e-07 29.3 0.0 4.3e-06 26.6 0.0 2.5 4 0 0 4 4 4 1 Uncharacterised protein domain (DUF2415) Ge1_WD40 PF16529.5 EIM91550.1 - 0.058 12.3 0.1 6.7 5.6 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein 17kDa_Anti_2 PF16998.5 EIM91550.1 - 0.2 11.6 2.7 0.25 11.3 0.2 2.2 2 0 0 2 2 2 0 17 kDa outer membrane surface antigen WD40 PF00400.32 EIM91550.1 - 0.22 12.5 2.4 87 4.2 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat DFRP_C PF16543.5 EIM91552.1 - 3.4e-30 104.4 2.0 3.4e-30 104.4 2.0 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 EIM91552.1 - 2.5e-06 27.4 18.5 0.00031 20.7 7.4 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 EIM91552.1 - 6.3e-05 22.8 13.1 0.0001 22.1 2.9 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EIM91552.1 - 0.00016 22.3 18.6 0.0051 17.5 6.2 3.9 2 1 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 EIM91552.1 - 0.0022 17.7 11.1 0.054 13.3 3.7 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EIM91552.1 - 0.0023 18.1 1.8 0.6 10.4 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EIM91552.1 - 0.08 13.4 10.6 0.56 10.8 4.1 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF2599 PF10783.9 EIM91552.1 - 1.1 9.9 4.2 1.1 9.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) FOXP-CC PF16159.5 EIM91552.1 - 2.2 9.0 5.4 7.8 7.2 0.0 3.3 3 1 0 3 3 3 0 FOXP coiled-coil domain Coq4 PF05019.13 EIM91553.1 - 1.8e-97 325.0 0.0 2.1e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF3638 PF12340.8 EIM91555.1 - 5.2e-85 284.4 0.9 9.4e-85 283.5 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EIM91555.1 - 1.1e-17 63.0 0.1 4.9e-17 61.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) Torus PF16131.5 EIM91556.1 - 9.4e-40 135.7 1.8 1.7e-39 134.9 1.8 1.4 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EIM91556.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIM91556.1 - 0.00011 22.1 0.1 0.00019 21.3 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 EIM91556.1 - 0.034 14.2 5.1 0.059 13.4 5.1 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 EIM91556.1 - 0.47 10.3 8.4 0.76 9.7 8.4 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 EIM91556.1 - 0.59 10.1 6.6 1.1 9.3 6.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ADH_zinc_N PF00107.26 EIM91557.1 - 2.8e-10 40.3 0.0 4.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91557.1 - 1e-08 35.0 0.0 2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM91557.1 - 0.0069 17.4 0.0 0.014 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EIM91558.1 - 2.6e-12 46.8 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91558.1 - 0.00018 21.4 0.0 0.0005 19.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM91558.1 - 0.0011 20.0 0.0 0.004 18.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cpn10 PF00166.21 EIM91558.1 - 0.011 15.7 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit ADH_zinc_N PF00107.26 EIM91559.1 - 2.5e-13 50.1 0.0 4.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91559.1 - 2.6e-10 40.1 0.1 6.5e-10 38.9 0.1 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM91559.1 - 0.012 16.7 0.0 0.029 15.4 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EIM91559.1 - 0.037 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Aminotran_1_2 PF00155.21 EIM91560.1 - 6.3e-26 91.4 0.0 7.8e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EIM91560.1 - 5.1e-13 48.6 0.0 6.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 EIM91560.1 - 0.18 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HRXXH PF13933.6 EIM91560.1 - 0.21 11.1 0.0 0.47 10.0 0.0 1.5 2 0 0 2 2 2 0 Putative peptidase family Ribosomal_L4 PF00573.22 EIM91561.1 - 1.8e-41 142.0 1.9 1.8e-41 142.0 1.9 1.6 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EIM91561.1 - 2.6e-28 97.9 2.0 2.6e-28 97.9 2.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain ADH_zinc_N PF00107.26 EIM91562.1 - 3.4e-10 40.0 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91562.1 - 5.6e-09 35.9 0.0 1.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EIM91562.1 - 0.0061 17.6 0.0 0.017 16.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase CbiG_N PF11760.8 EIM91562.1 - 0.04 13.9 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal DJ-1_PfpI PF01965.24 EIM91564.1 - 1.3e-06 28.4 0.0 5.1e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family FNIP_C PF14638.6 EIM91565.1 - 0.069 12.8 0.2 6.2 6.4 0.1 2.2 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus OPT PF03169.15 EIM91566.1 - 3.5e-149 498.3 45.2 4e-149 498.1 45.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SLATT_1 PF18181.1 EIM91566.1 - 0.13 12.2 0.7 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Ala_racemase_N PF01168.20 EIM91567.1 - 2.8e-19 69.6 0.0 6.9e-19 68.4 0.0 1.6 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Hydrolase_like PF13242.6 EIM91567.1 - 0.091 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like SSF PF00474.17 EIM91568.1 - 8.2e-19 67.7 28.4 8.2e-19 67.7 28.4 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Tmemb_14 PF03647.13 EIM91569.1 - 2.8e-24 85.7 6.5 3.2e-24 85.5 6.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EIM91569.1 - 0.007 16.7 1.1 0.029 14.7 1.1 1.9 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DSPc PF00782.20 EIM91570.1 - 3.6e-26 91.5 0.0 7.1e-21 74.4 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIM91570.1 - 0.043 13.4 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase YL1 PF05764.13 EIM91570.1 - 1.9 8.6 11.5 1.5 8.9 0.1 2.4 2 0 0 2 2 2 0 YL1 nuclear protein DJ-1_PfpI PF01965.24 EIM91571.1 - 9.2e-05 22.3 0.0 0.00046 20.0 0.0 2.4 1 1 0 1 1 1 1 DJ-1/PfpI family DUF959 PF06121.14 EIM91572.1 - 1.5 9.1 11.3 0.035 14.4 1.8 2.2 1 1 0 2 2 2 0 Domain of Unknown Function (DUF959) Glyco_transf_22 PF03901.17 EIM91573.1 - 1.1e-13 51.3 8.3 1.5e-13 50.8 8.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ABC2_membrane PF01061.24 EIM91574.1 - 1.8e-36 125.6 18.1 1.8e-36 125.6 18.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EIM91574.1 - 1.3e-27 97.0 0.1 2.5e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIM91574.1 - 2.2e-05 24.5 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIM91574.1 - 0.0021 17.6 0.5 0.021 14.3 0.0 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 EIM91574.1 - 0.0029 16.8 22.6 0.007 15.5 22.6 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EIM91574.1 - 0.0036 17.0 0.1 0.0083 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EIM91574.1 - 0.004 17.1 0.1 0.0081 16.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EIM91574.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EIM91574.1 - 0.059 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EIM91574.1 - 0.063 13.8 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EIM91574.1 - 0.095 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Calici_MSP PF05752.11 EIM91574.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein AAA_28 PF13521.6 EIM91574.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EIM91574.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIM91574.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain EGF_2 PF07974.13 EIM91574.1 - 1.8 9.0 34.6 0.028 14.8 13.0 3.9 3 0 0 3 3 2 0 EGF-like domain Glyco_transf_22 PF03901.17 EIM91575.1 - 1.6e-37 129.7 20.3 2.1e-37 129.4 20.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aldose_epim PF01263.20 EIM91577.1 - 8.8e-12 44.9 0.0 2.9e-08 33.4 0.0 2.4 1 1 1 2 2 2 2 Aldose 1-epimerase RNase_H PF00075.24 EIM91578.1 - 1.9e-26 92.9 0.0 3e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 RNase H Cauli_VI PF01693.16 EIM91578.1 - 1.4e-19 70.1 1.2 3.5e-19 68.8 1.2 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin zf-MYND PF01753.18 EIM91579.1 - 7.7e-10 38.7 10.5 1.6e-09 37.7 10.5 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EIM91579.1 - 0.023 14.8 3.4 0.023 14.8 3.4 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CCCH_3 PF15663.5 EIM91579.1 - 0.025 14.8 0.0 0.025 14.8 0.0 1.9 2 1 1 3 3 3 0 Zinc-finger containing family zf-C6H2 PF15801.5 EIM91579.1 - 3.9 7.9 13.0 0.88 9.9 8.8 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EIM91580.1 - 5.4e-11 42.4 4.8 1.3e-10 41.2 4.8 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM91580.1 - 0.79 10.1 7.5 2.7 8.4 7.5 2.0 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pkinase PF00069.25 EIM91581.1 - 1e-43 149.6 0.0 3.9e-43 147.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91581.1 - 2.7e-23 82.6 0.1 4.4e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM91581.1 - 1.1e-05 24.4 0.0 1.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM91581.1 - 0.00013 22.0 0.2 0.00086 19.3 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM91581.1 - 0.00051 19.4 0.1 0.59 9.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like UPF0014 PF03649.13 EIM91583.1 - 8.4e-69 231.6 19.9 1e-68 231.3 19.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) OATP PF03137.20 EIM91583.1 - 0.01 14.2 1.1 0.025 12.9 1.1 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MIS13 PF08202.11 EIM91584.1 - 1.2e-20 74.0 4.4 3e-20 72.7 4.2 1.7 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Sec8_exocyst PF04048.14 EIM91585.1 - 1.1 9.1 15.6 0.16 11.8 6.8 2.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain CENP-F_leu_zip PF10473.9 EIM91585.1 - 1.6 8.8 37.0 0.77 9.8 5.1 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cob_adeno_trans PF01923.18 EIM91585.1 - 1.9 8.6 15.0 0.79 9.8 9.3 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spc7 PF08317.11 EIM91585.1 - 2.7 6.8 35.0 8 5.2 34.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 EIM91585.1 - 9.6 5.5 24.0 1.1 8.5 18.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.26 EIM91586.1 - 1.7e-12 47.1 15.6 0.00056 20.2 0.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM91586.1 - 6.4e-08 32.8 12.5 0.03 15.2 2.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM91586.1 - 0.0042 17.3 1.8 7.6 7.0 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EIM91586.1 - 0.0074 16.7 8.6 0.13 12.8 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EIM91586.1 - 0.015 15.3 7.7 0.11 12.5 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Fer4_9 PF13187.6 EIM91586.1 - 0.093 12.9 1.5 0.21 11.8 1.5 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-BED PF02892.15 EIM91586.1 - 0.64 10.1 2.9 0.69 10.0 0.6 2.1 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.7 EIM91586.1 - 3.1 8.3 5.2 38 4.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type YL1 PF05764.13 EIM91586.1 - 8.5 6.4 19.7 0.28 11.3 5.3 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Gln-synt_C PF00120.24 EIM91587.1 - 4e-68 230.0 0.0 5.5e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EIM91587.1 - 9.1e-05 22.3 0.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain Prog_receptor PF02161.15 EIM91587.1 - 0.013 14.3 0.2 0.02 13.7 0.2 1.3 1 0 0 1 1 1 0 Progesterone receptor Gln-synt_C PF00120.24 EIM91588.1 - 3.3e-66 223.6 0.0 4.5e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EIM91588.1 - 4.2e-07 29.8 0.0 1.5e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain Prog_receptor PF02161.15 EIM91588.1 - 0.017 13.9 0.4 0.025 13.3 0.4 1.2 1 0 0 1 1 1 0 Progesterone receptor HMG_box PF00505.19 EIM91590.1 - 9.6e-07 29.1 4.6 2.1e-06 28.0 4.6 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 EIM91590.1 - 0.0014 19.3 0.2 0.0014 19.3 0.2 1.9 1 1 1 2 2 2 1 YABBY protein HMG_box_2 PF09011.10 EIM91590.1 - 0.0058 17.2 3.8 0.0094 16.5 3.8 1.5 1 1 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EIM91590.1 - 0.011 16.3 0.3 0.011 16.3 0.3 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 Ribosomal_60s PF00428.19 EIM91590.1 - 9.5 6.9 15.2 15 6.2 15.2 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein PS_Dcarbxylase PF02666.15 EIM91592.1 - 1.1e-58 198.1 0.0 1.7e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EIM91592.1 - 1e-36 125.3 0.0 2.7e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 EIM91592.1 - 0.0069 16.8 0.1 0.015 15.7 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EIM91592.1 - 0.031 14.2 0.0 0.41 10.7 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain PRRSV_2b PF07069.11 EIM91593.1 - 1.2 9.7 6.8 0.25 11.8 0.3 2.7 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b SPATA3 PF15662.5 EIM91594.1 - 0.43 11.2 7.9 0.5 11.0 7.9 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family PMT_4TMC PF16192.5 EIM91596.1 - 0.022 14.4 0.3 0.022 14.4 0.3 2.0 2 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase DUF3989 PF13150.6 EIM91596.1 - 0.44 10.3 0.0 0.44 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) DUF4191 PF13829.6 EIM91601.1 - 3.8 6.8 5.2 3.4 6.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TBPIP PF07106.13 EIM91602.1 - 4.8e-17 61.6 0.1 9e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain bZIP_1 PF00170.21 EIM91602.1 - 0.00087 19.3 1.1 0.00087 19.3 1.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor TMCO5 PF14992.6 EIM91602.1 - 0.0011 18.6 1.6 0.0018 17.9 1.6 1.2 1 0 0 1 1 1 1 TMCO5 family TrmB PF01978.19 EIM91602.1 - 0.019 14.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB SOGA PF11365.8 EIM91602.1 - 0.074 14.2 1.6 0.16 13.1 0.9 1.9 2 0 0 2 2 2 0 Protein SOGA APG6_N PF17675.1 EIM91602.1 - 0.24 11.9 3.6 0.093 13.3 0.9 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 EIM91602.1 - 0.29 11.6 8.2 0.87 10.1 5.7 2.5 2 1 0 2 2 2 0 Cell division protein ZapB Mito_carr PF00153.27 EIM91603.1 - 1.6e-52 175.4 4.8 9e-21 73.6 0.0 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIM91603.1 - 0.0044 16.2 0.0 0.49 9.5 0.0 2.7 2 0 0 2 2 2 2 Gammaproteobacterial serine protease GalKase_gal_bdg PF10509.9 EIM91604.1 - 4.7e-21 74.1 0.0 8.4e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EIM91604.1 - 1.3e-13 50.9 2.2 3.9e-13 49.4 1.6 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EIM91604.1 - 1e-08 35.4 0.2 2.3e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Fungal_trans PF04082.18 EIM91605.1 - 4.7e-25 88.1 0.0 6.7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM91605.1 - 1.2e-10 41.3 9.6 2.3e-10 40.4 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EIM91605.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain Metallophos PF00149.28 EIM91606.1 - 1.4e-09 38.8 0.5 2.1e-09 38.2 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Beta_helix PF13229.6 EIM91607.1 - 3.9e-06 26.8 8.3 1.6e-05 24.9 7.2 2.0 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EIM91607.1 - 0.0053 16.1 0.6 0.0085 15.4 0.6 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Zn_clus PF00172.18 EIM91608.1 - 5.6e-06 26.4 11.0 1.1e-05 25.4 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 EIM91610.1 - 1.9e-12 48.1 0.2 2.9e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPI_Ypi1 PF07491.11 EIM91611.1 - 3.6e-25 87.6 2.3 3.6e-25 87.6 2.3 1.9 2 1 0 2 2 2 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 EIM91611.1 - 0.1 11.2 5.9 0.13 10.9 5.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EIM91611.1 - 0.25 9.6 0.7 0.28 9.4 0.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.14 EIM91611.1 - 0.26 10.6 4.4 0.32 10.4 4.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_hydro_18 PF00704.28 EIM91612.1 - 7.1e-22 78.5 6.8 6.6e-21 75.4 6.8 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 zf-MYND PF01753.18 EIM91613.1 - 4.3e-11 42.7 8.8 1.1e-10 41.4 8.8 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EIM91613.1 - 0.044 14.1 7.5 0.089 13.1 7.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding IDO PF01231.18 EIM91614.1 - 3.4e-138 461.1 0.0 3.9e-138 460.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Methyltransf_11 PF08241.12 EIM91615.1 - 1.1e-13 51.6 0.0 1.8e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM91615.1 - 2.6e-12 47.3 0.0 4.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM91615.1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91615.1 - 2.1e-06 28.4 0.0 3.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM91615.1 - 0.011 15.6 0.0 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EIM91615.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EIM91615.1 - 0.032 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_28 PF02636.17 EIM91615.1 - 0.092 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 EIM91616.1 - 2.8e-13 50.3 0.0 4.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM91616.1 - 4.5e-11 43.3 0.0 8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91616.1 - 3.8e-06 27.6 0.0 6.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM91616.1 - 1.4e-05 25.0 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM91616.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EIM91616.1 - 0.045 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 EIM91616.1 - 0.05 13.4 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 EIM91616.1 - 0.053 12.6 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 EIM91616.1 - 0.15 11.6 0.0 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 EIM91617.1 - 4.7e-13 49.6 0.0 9.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM91617.1 - 2e-11 44.4 0.0 3.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM91617.1 - 5.4e-06 26.3 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91617.1 - 3.3e-05 24.5 0.0 6.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 EIM91617.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 EIM91617.1 - 0.063 13.1 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 EIM91618.1 - 2.1e-11 43.7 0.0 4.7e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM91618.1 - 0.026 14.7 0.0 0.084 13.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DDE_1 PF03184.19 EIM91619.1 - 6.8e-37 126.8 0.0 8.4e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease EzrA PF06160.12 EIM91620.1 - 0.00075 17.8 8.6 0.001 17.4 8.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FPP PF05911.11 EIM91620.1 - 0.001 17.4 12.9 0.0014 16.9 12.9 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil KASH_CCD PF14662.6 EIM91620.1 - 0.0045 16.8 13.0 0.0091 15.8 13.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 EIM91620.1 - 0.0088 14.2 10.6 0.014 13.6 10.6 1.2 1 0 0 1 1 1 1 HOOK protein YabA PF06156.13 EIM91620.1 - 0.039 14.6 7.0 0.99 10.1 1.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CdvA PF18822.1 EIM91620.1 - 0.18 11.7 8.9 0.15 11.9 3.4 2.6 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Leu_zip PF15294.6 EIM91620.1 - 0.22 11.0 9.0 0.33 10.4 9.0 1.2 1 0 0 1 1 1 0 Leucine zipper HeLo PF14479.6 EIM91620.1 - 0.28 11.0 12.6 1.3 8.8 10.4 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation ING PF12998.7 EIM91620.1 - 0.58 10.8 3.6 0.64 10.6 2.1 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4200 PF13863.6 EIM91620.1 - 1.6 9.2 13.2 3.8 7.9 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4472 PF14739.6 EIM91620.1 - 2 9.2 10.2 0.94 10.2 2.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) BLOC1_2 PF10046.9 EIM91620.1 - 2.6 8.4 7.1 11 6.4 3.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1465 PF07323.12 EIM91620.1 - 3.3 7.6 13.7 0.44 10.4 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DNA_repr_REX1B PF14966.6 EIM91620.1 - 3.5 8.3 7.7 1.7 9.4 1.7 2.3 1 1 1 2 2 2 0 DNA repair REX1-B DUF1664 PF07889.12 EIM91620.1 - 3.9 7.5 5.2 25 4.9 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EIM91620.1 - 5.4 6.2 7.2 3.5 6.8 5.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 EIM91620.1 - 5.8 6.1 18.6 0.41 9.9 4.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EIM91620.1 - 6.4 6.9 6.9 13 6.0 6.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 EIM91620.1 - 8.3 6.7 13.0 2.1 8.6 4.5 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein TPR_MLP1_2 PF07926.12 EIM91620.1 - 8.4 6.5 21.3 12 5.9 3.1 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 EIM91620.1 - 9.8 6.5 6.2 9.5 6.5 3.7 2.2 1 1 1 2 2 2 0 Haemolysin XhlA RVT_1 PF00078.27 EIM91622.1 - 2.2e-10 40.4 0.3 3.4e-10 39.8 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EIM91622.1 - 3.8e-06 26.9 0.0 8.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 EIM91623.1 - 7.1e-08 32.2 3.0 1.5e-07 31.2 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 EIM91623.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EIM91623.1 - 0.015 15.9 0.0 0.045 14.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EIM91623.1 - 0.032 14.8 0.0 0.082 13.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 EIM91623.1 - 0.04 13.9 0.3 0.17 11.8 0.3 2.1 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EIM91623.1 - 0.063 13.0 6.7 0.13 12.0 6.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EIM91623.1 - 0.076 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2B PF12384.8 EIM91623.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase zf-CCHC_2 PF13696.6 EIM91623.1 - 0.39 10.6 3.2 0.73 9.7 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Cytochrom_C PF00034.21 EIM91626.1 - 4.9e-09 37.2 0.1 6.9e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EIM91626.1 - 1.5e-06 28.4 3.3 1.8e-05 25.0 3.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EIM91626.1 - 0.0023 17.6 0.1 0.027 14.2 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain FAD_binding_3 PF01494.19 EIM91628.1 - 9.1e-16 58.0 0.0 3.5e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 EIM91628.1 - 0.00052 19.0 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EIM91628.1 - 0.023 14.9 0.1 0.059 13.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM91628.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EIM91628.1 - 0.1 11.8 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EIM91628.1 - 0.24 10.4 0.0 2.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.19 EIM91629.1 - 0.0014 17.9 0.1 0.0045 16.3 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EIM91629.1 - 0.0062 15.4 0.1 0.012 14.5 0.0 1.4 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EIM91629.1 - 0.007 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM91629.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EIM91629.1 - 0.2 10.8 0.0 0.89 8.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM91630.1 - 7.9e-15 54.9 0.5 1.3e-08 34.5 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 EIM91630.1 - 2.8e-05 23.1 0.0 4.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EIM91630.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM91630.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.10 EIM91630.1 - 0.079 12.0 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EIM91630.1 - 0.2 10.8 0.0 0.43 9.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIM91632.1 - 2.5e-11 43.4 0.8 3.3e-10 39.7 0.8 2.5 1 1 0 1 1 1 1 FAD binding domain MCR_beta PF02241.18 EIM91632.1 - 0.031 13.9 0.0 0.097 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain NAD_binding_8 PF13450.6 EIM91632.1 - 0.032 14.5 0.2 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.25 EIM91633.1 - 1.5e-27 96.4 0.0 1.8e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM91633.1 - 3.4e-13 49.7 0.0 4.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM91633.1 - 2.1e-06 27.8 0.1 4.1e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIM91633.1 - 8.6e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EIM91633.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 EIM91633.1 - 0.0073 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YjeF_N PF03853.15 EIM91633.1 - 0.028 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 EIM91633.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EIM91633.1 - 0.048 14.1 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Helicase_RecD PF05127.14 EIM91633.1 - 0.058 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Helicase DFP PF04127.15 EIM91633.1 - 0.092 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_Gly3P_dh_N PF01210.23 EIM91633.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EIM91633.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3681 PF12442.8 EIM91633.1 - 0.76 10.3 3.2 2.2 8.8 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3681) FA_desaturase PF00487.24 EIM91634.1 - 2.6e-15 56.9 21.1 2.6e-15 56.9 21.1 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIM91634.1 - 1.3e-10 41.3 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aminotran_1_2 PF00155.21 EIM91635.1 - 1.3e-29 103.5 0.0 1.8e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EIM91635.1 - 0.039 13.2 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Acetyltransf_7 PF13508.7 EIM91636.1 - 5.6e-06 26.7 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM91636.1 - 4.2e-05 23.5 0.0 8.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM91636.1 - 0.0024 18.1 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EIM91636.1 - 0.017 15.2 0.0 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain p450 PF00067.22 EIM91637.1 - 1.1e-68 232.1 0.4 2.4e-68 231.0 0.4 1.4 1 1 0 1 1 1 1 Cytochrome P450 TFIIF_beta PF02270.15 EIM91639.1 - 4e-28 97.3 0.1 6.9e-28 96.6 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EIM91639.1 - 2.3e-17 63.9 0.1 5.2e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus DUF3591 PF12157.8 EIM91639.1 - 0.0021 16.8 0.2 0.0028 16.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) BTB PF00651.31 EIM91640.1 - 6e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SnoaL_2 PF12680.7 EIM91641.1 - 7e-08 33.0 0.5 1.4e-07 32.1 0.5 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EIM91641.1 - 3.8e-06 26.7 0.1 7.9e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Glyco_hydro_61 PF03443.14 EIM91642.1 - 9.1e-71 238.0 0.0 9.1e-71 238.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Utp14 PF04615.13 EIM91642.1 - 3.9 5.9 5.7 5 5.6 5.7 1.0 1 0 0 1 1 1 0 Utp14 protein Pol_alpha_B_N PF08418.10 EIM91642.1 - 8.7 6.2 11.8 13 5.6 11.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal ABC_membrane PF00664.23 EIM91643.1 - 2.4e-43 148.8 8.2 3e-43 148.4 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIM91643.1 - 2.4e-34 118.8 0.0 6.2e-34 117.4 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 EIM91643.1 - 4.9e-07 29.4 0.0 3.1e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EIM91643.1 - 0.00094 19.1 0.0 0.084 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EIM91643.1 - 0.0017 18.7 0.2 0.034 14.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EIM91643.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 EIM91643.1 - 0.0063 16.9 0.1 0.017 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EIM91643.1 - 0.0086 16.5 0.0 0.14 12.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EIM91643.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EIM91643.1 - 0.02 15.1 1.0 0.44 10.8 1.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EIM91643.1 - 0.043 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EIM91643.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EIM91643.1 - 0.082 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 EIM91644.1 - 2e-34 118.8 0.0 2.7e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM91644.1 - 8.4e-28 97.5 0.0 1.2e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM91644.1 - 4.8e-06 26.2 0.0 8.5e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM91644.1 - 0.00045 20.2 0.0 0.00092 19.2 0.0 1.5 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EIM91644.1 - 0.011 15.2 0.1 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 EIM91646.1 - 2.3e-13 50.3 0.0 3.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM91646.1 - 2.9e-07 30.3 0.0 9.4e-07 28.7 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 EIM91646.1 - 0.0055 16.6 0.1 0.009 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EIM91646.1 - 0.033 13.7 0.4 0.058 12.8 0.4 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Patatin PF01734.22 EIM91647.1 - 3.7e-24 86.0 0.0 6.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.6 EIM91648.1 - 9.4e-84 273.3 0.4 9.2e-12 44.4 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 EIM91648.1 - 1.6e-75 249.4 3.5 8.2e-15 54.9 0.0 7.0 1 1 7 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 EIM91648.1 - 1e-26 91.0 0.7 0.0024 17.8 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 EIM91648.1 - 1.7e-16 59.3 1.5 0.23 11.9 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91648.1 - 6e-13 48.0 4.6 3 7.8 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM91648.1 - 1.6e-12 46.5 0.9 2.1 8.7 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat Urocanase_N PF17391.2 EIM91648.1 - 4.8e-09 36.0 0.0 5.3 6.7 0.0 6.1 6 0 0 6 6 6 1 Urocanase N-terminal domain TPR_16 PF13432.6 EIM91648.1 - 5.3e-09 36.6 0.0 1.2 9.8 0.0 6.0 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM91648.1 - 4.1e-08 33.0 0.7 0.00012 21.6 0.1 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 EIM91648.1 - 5.4e-07 30.0 0.0 5.1 7.7 0.0 6.4 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIM91648.1 - 2.5e-05 24.7 0.4 60 4.8 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1768 PF08719.11 EIM91648.1 - 3.5e-05 24.1 0.1 0.031 14.5 0.0 3.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1768) TPR_8 PF13181.6 EIM91648.1 - 4e-05 23.5 5.1 25 5.4 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIM91648.1 - 0.00024 21.4 0.0 27 5.8 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TF_AP-2 PF03299.14 EIM91648.1 - 0.001 19.0 1.3 55 3.6 0.0 5.5 6 0 0 6 6 6 0 Transcription factor AP-2 TPR_5 PF12688.7 EIM91648.1 - 0.0093 16.2 0.3 51 4.1 0.0 4.3 3 1 2 5 5 5 0 Tetratrico peptide repeat Spectrin PF00435.21 EIM91648.1 - 0.013 16.0 0.5 2.2 8.8 0.0 3.1 3 0 0 3 3 3 0 Spectrin repeat Peptidase_S28 PF05577.12 EIM91648.1 - 0.055 12.3 0.0 5 5.8 0.0 3.1 1 1 1 3 3 3 0 Serine carboxypeptidase S28 DCAF17 PF15802.5 EIM91648.1 - 0.11 11.2 0.0 10 4.7 0.0 3.6 5 0 0 5 5 5 0 DDB1- and CUL4-associated factor 17 PPAK PF02818.15 EIM91648.1 - 0.86 9.8 3.5 20 5.5 0.0 4.3 6 0 0 6 6 4 0 PPAK motif Metallophos_2 PF12850.7 EIM91650.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 EIM91651.1 - 7.3e-12 45.2 0.0 2.4e-07 30.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91651.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM91652.1 - 0.22 10.9 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain TPR_10 PF13374.6 EIM91653.1 - 5.2e-141 455.3 13.7 2.7e-13 49.3 0.1 11.9 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 EIM91653.1 - 2.7e-115 376.8 33.7 7e-15 55.1 0.3 10.7 1 1 9 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 EIM91653.1 - 4.6e-40 132.7 14.4 0.013 15.5 0.0 11.3 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_17 PF13431.6 EIM91653.1 - 3.8e-24 83.3 8.9 0.4 11.2 0.0 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 EIM91653.1 - 2.6e-23 80.2 13.7 0.45 10.7 0.0 11.1 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91653.1 - 2.8e-23 80.7 15.8 0.52 10.2 0.1 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 EIM91653.1 - 6e-23 81.2 8.4 0.019 15.6 0.0 10.4 6 4 4 10 10 10 6 Tetratricopeptide repeat TPR_4 PF07721.14 EIM91653.1 - 1.3e-21 74.9 1.7 0.67 10.7 0.1 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM91653.1 - 3.9e-19 68.9 1.6 0.55 10.8 0.0 10.4 1 1 10 11 11 11 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM91653.1 - 2.3e-17 63.4 13.7 2.3e-06 27.2 0.8 4.2 1 1 3 4 4 4 4 MalT-like TPR region TPR_8 PF13181.6 EIM91653.1 - 1.7e-11 43.4 13.0 1.5 9.2 0.0 10.3 11 0 0 11 11 11 3 Tetratricopeptide repeat Urocanase_N PF17391.2 EIM91653.1 - 4.7e-06 26.3 0.0 57 3.4 0.0 7.9 9 1 1 10 10 10 0 Urocanase N-terminal domain TPR_14 PF13428.6 EIM91653.1 - 1.5e-05 25.4 18.4 13 6.9 0.0 9.9 11 0 0 11 11 10 0 Tetratricopeptide repeat RadC PF04002.15 EIM91653.1 - 6.5e-05 22.9 1.9 21 5.1 0.0 6.9 1 1 6 8 8 8 0 RadC-like JAB domain TPR_3 PF07720.12 EIM91653.1 - 8.6e-05 22.4 1.9 12 6.1 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3485 PF11984.8 EIM91653.1 - 0.00047 20.0 0.7 6.6 6.4 0.0 4.7 2 2 1 3 3 3 1 Protein of unknown function (DUF3485) DUF4119 PF13494.6 EIM91653.1 - 0.0091 16.1 2.6 53 4.1 0.0 6.0 3 2 6 9 9 8 0 Domain of unknown function, B. Theta Gene description (DUF4119) PPR PF01535.20 EIM91653.1 - 0.034 14.4 0.6 1.2e+02 3.3 0.0 5.5 7 0 0 7 7 5 0 PPR repeat Peptidase_S28 PF05577.12 EIM91653.1 - 0.096 11.5 0.1 22 3.7 0.0 3.8 2 1 3 5 5 5 0 Serine carboxypeptidase S28 DCAF17 PF15802.5 EIM91653.1 - 0.13 10.9 0.0 19 3.8 0.0 4.0 6 0 0 6 6 6 0 DDB1- and CUL4-associated factor 17 PPAK PF02818.15 EIM91653.1 - 0.45 10.7 2.0 51 4.1 0.0 4.3 6 0 0 6 6 4 0 PPAK motif DUF3890 PF13029.6 EIM91653.1 - 1.7 9.2 9.2 1.5e+02 2.9 0.0 6.5 9 0 0 9 9 7 0 Domain of unknown function (DUF3890) Patatin PF01734.22 EIM91654.1 - 1.2e-19 71.3 0.0 1.7e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Metallophos_2 PF12850.7 EIM91655.1 - 0.064 13.5 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 EIM91658.1 - 5.3e-15 55.5 0.0 7.3e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91658.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_10 PF13374.6 EIM91659.1 - 1.1e-78 257.1 0.2 9.9e-11 41.2 0.0 7.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 EIM91659.1 - 3.1e-60 200.4 2.6 1.1e-13 51.3 0.0 5.5 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EIM91659.1 - 1.6e-24 84.1 3.8 0.012 15.6 0.0 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91659.1 - 2.5e-13 49.2 0.2 1.1 9.2 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIM91659.1 - 5.4e-13 49.4 0.0 0.77 10.5 0.0 6.2 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM91659.1 - 2.9e-12 45.7 0.2 2.4 8.5 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIM91659.1 - 2.2e-11 43.3 1.9 0.88 10.1 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIM91659.1 - 3.7e-10 40.2 0.0 3.2 8.3 0.0 6.4 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 EIM91659.1 - 5.7e-07 29.6 0.0 14 6.6 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Urocanase_N PF17391.2 EIM91659.1 - 1.5e-06 27.9 0.4 8.4 6.1 0.0 5.3 6 0 0 6 6 6 0 Urocanase N-terminal domain TPR_MalT PF17874.1 EIM91659.1 - 2.4e-05 23.9 2.9 0.0071 15.8 1.1 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EIM91659.1 - 3.9e-05 24.1 1.0 66 4.7 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Metallophos_3 PF14582.6 EIM91659.1 - 0.00095 18.6 0.1 11 5.3 0.0 3.6 2 1 2 4 4 4 0 Metallophosphoesterase, calcineurin superfamily DUF1924 PF09086.11 EIM91659.1 - 0.0024 18.2 0.4 18 5.8 0.0 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF1924) DUF4119 PF13494.6 EIM91659.1 - 0.034 14.3 1.0 11 6.2 0.0 4.1 2 2 4 6 6 6 0 Domain of unknown function, B. Theta Gene description (DUF4119) TPR_3 PF07720.12 EIM91659.1 - 0.043 13.8 0.0 6.2 6.9 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat FeS_assembly_P PF01883.19 EIM91659.1 - 0.05 13.8 0.0 13 6.1 0.0 3.7 4 0 0 4 4 4 0 Iron-sulfur cluster assembly protein DUF4835 PF16119.5 EIM91659.1 - 0.062 12.4 0.9 7.4 5.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4835) SNAP PF14938.6 EIM91659.1 - 0.084 12.3 0.0 19 4.5 0.0 3.2 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP ArdA PF07275.11 EIM91659.1 - 0.13 12.9 3.4 8.6 6.9 0.5 3.7 2 2 1 3 3 3 0 Antirestriction protein (ArdA) DUF2001 PF09393.10 EIM91659.1 - 0.13 12.3 2.6 30 4.6 0.0 4.3 5 1 0 5 5 5 0 Phage tail tube protein partial_CstF PF15861.5 EIM91659.1 - 0.2 11.4 1.0 22 4.9 0.0 3.5 3 0 0 3 3 3 0 Partial cleavage stimulation factor domain DUF3157 PF11355.8 EIM91659.1 - 0.37 10.4 4.9 14 5.3 0.1 3.3 1 1 2 4 4 4 0 Protein of unknown function (DUF3157) TPR_6 PF13174.6 EIM91659.1 - 9.7 7.1 8.3 1e+02 3.9 0.1 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat Metallophos_2 PF12850.7 EIM91660.1 - 0.083 13.1 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 EIM91661.1 - 2.9e-19 69.5 0.0 1.9e-10 40.6 0.0 2.7 2 2 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 EIM91661.1 - 0.00035 20.0 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EIM91661.1 - 0.00072 18.9 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_10 PF13374.6 EIM91662.1 - 3.2e-117 379.7 0.9 2.4e-11 43.1 0.0 11.0 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 EIM91662.1 - 7.4e-103 337.0 14.7 1.6e-14 53.9 0.0 9.8 1 1 9 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 EIM91662.1 - 2.4e-36 121.1 9.9 0.0015 18.4 0.0 9.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 EIM91662.1 - 3.1e-21 74.2 3.7 0.41 11.1 0.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EIM91662.1 - 2.4e-19 69.7 0.0 0.34 11.6 0.1 8.7 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91662.1 - 4.8e-18 64.2 4.7 2.8 7.9 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIM91662.1 - 1.8e-17 62.0 5.8 2.5 8.4 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EIM91662.1 - 1.7e-14 54.0 0.0 1.7 9.2 0.0 9.1 8 1 2 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 EIM91662.1 - 6.9e-12 44.8 0.0 10 7.1 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Urocanase_N PF17391.2 EIM91662.1 - 1.6e-11 44.0 0.7 7.7 6.2 0.0 8.5 7 2 1 9 9 9 0 Urocanase N-terminal domain TPR_14 PF13428.6 EIM91662.1 - 3.6e-10 39.8 5.5 18 6.5 0.0 8.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM91662.1 - 1.3e-09 37.9 5.4 5.1e-05 22.8 1.0 3.5 1 1 2 3 3 3 3 MalT-like TPR region DUF1697 PF08002.11 EIM91662.1 - 5.1e-06 27.0 0.4 0.76 10.2 0.0 4.1 1 1 4 5 5 5 2 Protein of unknown function (DUF1697) FeS_assembly_P PF01883.19 EIM91662.1 - 2.2e-05 24.5 0.8 16 5.7 0.0 6.3 8 0 0 8 8 8 0 Iron-sulfur cluster assembly protein DUF1924 PF09086.11 EIM91662.1 - 0.00064 20.0 0.3 33 4.9 0.0 5.6 2 2 6 8 8 8 0 Domain of unknown function (DUF1924) DCAF17 PF15802.5 EIM91662.1 - 0.0012 17.7 0.0 18 3.9 0.0 4.8 6 0 0 6 6 6 0 DDB1- and CUL4-associated factor 17 PTAC PF06130.12 EIM91662.1 - 0.0013 18.9 1.5 27 5.0 0.0 6.4 4 3 4 8 8 8 0 Phosphate propanoyltransferase TPR_5 PF12688.7 EIM91662.1 - 0.002 18.4 0.1 43 4.4 0.0 5.6 3 2 4 7 7 7 0 Tetratrico peptide repeat DUF2664 PF10867.8 EIM91662.1 - 0.0041 17.5 0.7 1.1e+02 3.3 0.0 6.0 9 0 0 9 9 6 0 Protein of unknown function (DUF2664) DUF2001 PF09393.10 EIM91662.1 - 0.019 14.9 1.8 61 3.6 0.0 5.7 7 0 0 7 7 7 0 Phage tail tube protein IL34 PF15036.6 EIM91662.1 - 0.058 13.4 2.9 30 4.6 0.0 5.0 4 2 2 6 6 6 0 Interleukin 34 DUF3890 PF13029.6 EIM91662.1 - 0.13 12.7 3.4 72 3.9 0.0 5.2 7 0 0 7 7 4 0 Domain of unknown function (DUF3890) DUF4119 PF13494.6 EIM91662.1 - 1.1 9.5 3.0 34 4.7 0.0 4.3 2 2 4 6 6 6 0 Domain of unknown function, B. Theta Gene description (DUF4119) TPR_6 PF13174.6 EIM91662.1 - 3.4 8.5 16.1 61 4.6 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Patatin PF01734.22 EIM91663.1 - 9.1e-13 48.8 0.0 9.1e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase Plectin PF00681.20 EIM91663.1 - 0.054 13.4 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat Fungal_trans PF04082.18 EIM91664.1 - 4.5e-20 71.8 0.7 6.2e-20 71.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain S10_plectin PF03501.15 EIM91665.1 - 1.1e-44 150.5 0.3 1.3e-44 150.2 0.3 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 EIM91665.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 EIM91665.1 - 0.13 12.3 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation Glyco_hydro_61 PF03443.14 EIM91666.1 - 2.7e-72 243.0 2.7 4.3e-72 242.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 HNH_2 PF13391.6 EIM91667.1 - 4.8e-08 33.0 0.0 1.3e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 EIM91669.1 - 2.7e-14 53.2 0.0 3.4e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EIM91669.1 - 1.8e-07 30.3 0.1 2.3e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIM91669.1 - 0.0004 20.4 0.1 0.0023 17.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIM91669.1 - 0.0022 17.4 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EIM91669.1 - 0.0044 16.6 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EIM91669.1 - 0.0056 16.1 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EIM91669.1 - 0.038 13.3 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase EcKinase PF02958.20 EIM91669.1 - 0.044 13.1 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Melibiase_2 PF16499.5 EIM91672.1 - 4.5e-53 180.3 0.0 6.2e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 EIM91672.1 - 8.5e-06 24.9 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_C PF17801.1 EIM91672.1 - 0.015 15.3 0.1 0.049 13.7 0.1 1.9 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain Fungal_trans PF04082.18 EIM91674.1 - 2e-32 112.3 0.0 3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM91674.1 - 4.2e-09 36.4 9.7 8.3e-09 35.4 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 EIM91676.1 - 2.6e-07 30.8 1.0 0.01 16.2 0.2 4.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM91676.1 - 3.6e-05 23.4 0.3 0.22 11.3 0.2 4.3 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.33 EIM91676.1 - 0.0004 20.5 3.8 0.39 11.4 0.4 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 EIM91676.1 - 0.0022 17.9 10.5 0.23 11.6 0.2 5.5 7 0 0 7 7 7 2 Leucine Rich repeat Melibiase_2 PF16499.5 EIM91677.1 - 2.4e-52 177.9 0.0 3.4e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 EIM91677.1 - 6.7e-06 25.3 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_C PF17801.1 EIM91677.1 - 0.016 15.3 0.1 0.049 13.7 0.1 1.8 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain Topo-VIb_trans PF09239.11 EIM91679.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Topoisomerase VI B subunit, transducer Mlf1IP PF10248.9 EIM91679.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein TPR_10 PF13374.6 EIM91680.1 - 6.6e-09 35.4 5.3 0.72 9.8 0.0 5.1 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EIM91680.1 - 1.7e-06 28.4 4.2 0.0052 17.5 0.0 4.8 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM91680.1 - 6.9e-06 25.8 4.0 0.007 16.4 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM91680.1 - 6.1e-05 23.2 7.8 0.046 14.0 0.3 5.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91680.1 - 0.00032 20.4 7.6 0.0061 16.3 0.3 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIM91680.1 - 0.0025 18.3 0.6 1.8 9.2 0.3 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIM91680.1 - 0.0027 17.8 3.8 0.064 13.5 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM91680.1 - 0.0031 17.2 0.4 0.11 12.1 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 EIM91680.1 - 0.0054 17.3 0.5 2 9.1 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIM91680.1 - 0.011 16.4 0.8 21 6.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EIM91680.1 - 0.028 13.8 0.7 0.31 10.4 0.4 2.6 1 1 0 2 2 2 0 MalT-like TPR region F-box-like PF12937.7 EIM91681.1 - 0.016 15.1 0.1 0.043 13.7 0.1 1.7 1 0 0 1 1 1 0 F-box-like RCDG1 PF15725.5 EIM91681.1 - 0.69 10.4 4.6 1.8 9.1 4.6 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Ifi-6-16 PF06140.13 EIM91683.1 - 7.4e-09 35.4 29.7 7.4e-09 35.4 29.7 2.0 2 1 0 2 2 2 1 Interferon-induced 6-16 family NTP_transf_2 PF01909.23 EIM91684.1 - 1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EIM91684.1 - 6.5e-06 26.2 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Sec34 PF04136.15 EIM91685.1 - 1.3e-47 161.4 0.0 3.6e-47 160.0 0.0 1.8 1 0 0 1 1 1 1 Sec34-like family Sporozoite_P67 PF05642.11 EIM91685.1 - 0.61 8.1 6.0 0.93 7.5 6.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3772 PF12607.8 EIM91687.1 - 0.013 15.3 0.6 0.081 12.7 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) DUF87 PF01935.17 EIM91687.1 - 0.079 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain DUF1752 PF08550.10 EIM91688.1 - 1.3e-13 50.5 1.3 1.6e-13 50.2 1.3 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cellulase PF00150.18 EIM91689.1 - 1.8e-47 162.2 0.1 2.3e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EIM91689.1 - 2.1e-12 46.8 6.3 2.1e-12 46.8 6.3 2.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_10 PF00331.20 EIM91690.1 - 1.9e-60 204.7 0.0 2.1e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase PF00150.18 EIM91690.1 - 0.0066 15.9 0.0 0.032 13.7 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cu-oxidase PF00394.22 EIM91692.1 - 1.2e-38 132.7 0.0 8.5e-36 123.5 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM91692.1 - 2.8e-32 111.3 0.6 4.3e-30 104.2 0.0 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM91692.1 - 1.4e-27 96.0 0.0 3.3e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Ras PF00071.22 EIM91692.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Ras family Cu-oxidase_3 PF07732.15 EIM91693.1 - 3.2e-19 69.1 0.0 4.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cupin_1 PF00190.22 EIM91694.1 - 4.9e-32 110.6 0.0 4.5e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EIM91694.1 - 6.7e-25 86.6 0.0 2.3e-11 43.2 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EIM91694.1 - 5.2e-08 32.5 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EIM91694.1 - 1.8e-05 24.7 0.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EIM91694.1 - 0.00038 20.4 0.0 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 EIM91694.1 - 0.0038 16.7 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein ARD PF03079.14 EIM91694.1 - 0.034 14.3 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 EIM91694.1 - 0.052 13.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase PCO_ADO PF07847.12 EIM91694.1 - 0.092 12.2 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 PCO_ADO SSP160 PF06933.11 EIM91694.1 - 3.1 5.9 10.1 4.5 5.4 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dyp_perox PF04261.12 EIM91696.1 - 5.3e-05 22.4 0.1 0.00026 20.1 0.0 2.3 2 1 0 2 2 2 1 Dyp-type peroxidase family Exo_endo_phos PF03372.23 EIM91698.1 - 1.4e-10 41.1 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EIM91701.1 - 2e-17 62.7 10.3 2.8e-10 39.8 1.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EIM91701.1 - 5.2e-11 42.6 1.2 0.00042 20.6 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIM91701.1 - 0.0022 18.3 3.1 6 7.8 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 EIM91701.1 - 0.013 15.0 1.1 0.02 14.4 1.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Fungal_trans PF04082.18 EIM91702.1 - 7.1e-23 81.0 0.0 1.4e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM91702.1 - 1.4e-08 34.7 10.2 2.8e-08 33.7 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.15 EIM91703.1 - 0.011 15.5 14.4 0.054 13.3 4.4 2.9 3 0 0 3 3 3 0 Septum formation initiator DUF1635 PF07795.11 EIM91703.1 - 0.027 14.3 6.1 0.055 13.3 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CENP-F_leu_zip PF10473.9 EIM91703.1 - 0.13 12.3 13.5 0.019 15.0 8.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 USP8_interact PF08941.10 EIM91703.1 - 0.18 11.6 1.4 0.41 10.5 1.4 1.6 1 0 0 1 1 1 0 USP8 interacting SIKE PF05769.11 EIM91703.1 - 0.31 10.9 9.2 0.51 10.3 9.2 1.3 1 0 0 1 1 1 0 SIKE family Cnn_1N PF07989.11 EIM91703.1 - 0.82 9.9 11.8 10 6.3 7.5 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 CEP209_CC5 PF16574.5 EIM91703.1 - 1.2 9.4 11.5 3.1 8.0 8.1 2.4 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 FlaC_arch PF05377.11 EIM91703.1 - 1.2 9.6 6.1 0.49 10.8 2.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RBD-FIP PF09457.10 EIM91703.1 - 1.4 8.9 5.6 1.9 8.5 1.8 2.6 2 0 0 2 2 2 0 FIP domain Atg14 PF10186.9 EIM91703.1 - 7.9 5.5 9.1 14 4.6 9.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EIM91703.1 - 8.3 6.5 16.9 0.12 12.4 7.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pyr_redox_2 PF07992.14 EIM91705.1 - 1.3e-07 31.1 0.0 3.1e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIM91705.1 - 4.9e-06 26.0 0.0 0.0013 18.1 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 EIM91705.1 - 0.00045 20.7 0.3 0.0072 16.8 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Pyr_redox PF00070.27 EIM91705.1 - 0.0079 16.7 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM91705.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EIM91705.1 - 0.048 12.8 0.1 0.33 10.1 0.0 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIM91706.1 - 1.5e-11 44.1 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM91706.1 - 1.3e-08 34.9 0.1 6.8e-07 29.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM91706.1 - 5.9e-08 32.7 0.0 6.8e-05 22.6 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM91706.1 - 2.7e-07 30.7 0.0 9.1e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EIM91706.1 - 2.2e-05 23.9 0.0 0.0042 16.4 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM91706.1 - 0.00073 18.9 0.1 0.021 14.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EIM91706.1 - 0.0014 19.1 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EIM91706.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family K_oxygenase PF13434.6 EIM91706.1 - 0.015 14.5 0.2 2 7.5 0.0 3.4 4 1 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EIM91706.1 - 0.085 11.3 0.0 10 4.4 0.0 2.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Glyco_trans_4_4 PF13579.6 EIM91706.1 - 0.12 12.8 2.5 1.6 9.2 0.1 2.9 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain FMO-like PF00743.19 EIM91707.1 - 6.8e-15 54.5 0.2 1.5e-14 53.3 0.0 1.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EIM91707.1 - 1.4e-10 41.2 0.0 1.4e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM91707.1 - 2.1e-06 27.2 0.0 0.0042 16.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM91707.1 - 4.2e-06 26.1 0.2 0.00043 19.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EIM91707.1 - 5.3e-05 22.6 0.0 0.00046 19.5 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM91707.1 - 0.00013 21.7 2.6 0.0081 15.8 0.9 3.1 1 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM91707.1 - 0.014 15.4 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EIM91707.1 - 0.033 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM91707.1 - 0.17 11.0 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Ribonuclease_3 PF00636.26 EIM91708.1 - 0.0019 18.8 9.7 0.086 13.5 9.7 2.8 1 1 0 1 1 1 1 Ribonuclease III domain Borrelia_P83 PF05262.11 EIM91708.1 - 0.21 10.0 27.4 0.27 9.7 27.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein LAP1C PF05609.12 EIM91708.1 - 0.22 10.6 18.4 0.29 10.2 18.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 EIM91708.1 - 0.35 9.5 13.6 0.42 9.2 13.6 1.1 1 0 0 1 1 1 0 Hamartin protein CDC45 PF02724.14 EIM91708.1 - 0.36 9.1 14.6 0.54 8.5 14.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.13 EIM91708.1 - 0.69 9.5 28.0 0.98 9.0 28.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mitofilin PF09731.9 EIM91708.1 - 1.2 7.9 34.2 1.7 7.4 34.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GREB1 PF15782.5 EIM91708.1 - 1.2 6.1 19.8 4.8 4.2 20.9 1.4 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 EIM91708.1 - 2.7 8.0 23.1 4.2 7.4 23.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HCO3_cotransp PF00955.21 EIM91708.1 - 2.8 6.6 5.5 4.4 6.0 5.5 1.4 1 0 0 1 1 1 0 HCO3- transporter family DUF4776 PF16003.5 EIM91708.1 - 3.3 6.6 29.7 4.4 6.2 29.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF966 PF06136.13 EIM91708.1 - 7.5 6.2 21.4 9.9 5.8 21.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.16 EIM91708.1 - 8.6 6.3 15.5 12 5.8 15.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GP79 PF17463.2 EIM91709.1 - 0.039 13.9 0.2 0.089 12.8 0.0 1.7 2 0 0 2 2 2 0 Gene product 79 Phage_integrase PF00589.22 EIM91712.1 - 0.21 11.3 0.0 0.62 9.8 0.0 1.9 1 1 1 2 2 2 0 Phage integrase family PAP2 PF01569.21 EIM91712.1 - 0.87 9.4 4.6 0.37 10.6 2.2 1.9 2 1 0 2 2 2 0 PAP2 superfamily MFS_1 PF07690.16 EIM91713.1 - 1.3e-29 103.2 31.9 1.6e-29 103.0 31.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GST_N_3 PF13417.6 EIM91714.1 - 4e-07 30.4 0.0 9.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM91714.1 - 2e-06 27.7 0.1 3.8e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EIM91714.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM91714.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rotamase PF00639.21 EIM91715.1 - 1.9e-22 80.0 0.0 2.4e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EIM91715.1 - 3.2e-22 79.2 0.0 4.6e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EIM91715.1 - 4.6e-08 33.0 0.1 4.6e-08 33.0 0.1 2.1 3 0 0 3 3 3 1 WW domain Rotamase_2 PF13145.6 EIM91715.1 - 2.7e-05 25.0 0.0 3.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Aldedh PF00171.22 EIM91718.1 - 7.1e-180 598.4 0.0 8e-180 598.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM91718.1 - 0.00079 18.6 0.0 0.0019 17.3 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1411 PF07199.11 EIM91718.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) zf-MYND PF01753.18 EIM91719.1 - 7.9e-05 22.7 11.6 7.9e-05 22.7 11.6 1.9 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EIM91719.1 - 0.065 13.1 9.1 0.14 12.1 9.1 1.5 1 0 0 1 1 1 0 HIT zinc finger Transp_Tc5_C PF04236.15 EIM91719.1 - 0.091 13.1 1.5 0.19 12.1 1.5 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-C6H2 PF15801.5 EIM91719.1 - 0.24 11.7 7.5 0.45 10.9 7.5 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 EIM91720.1 - 1.6e-28 99.6 50.9 1.4e-22 80.2 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM91720.1 - 1.8e-07 30.4 32.4 0.00059 18.8 9.2 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Aldedh PF00171.22 EIM91722.1 - 1.2e-181 604.3 0.0 1.4e-181 604.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM91722.1 - 0.057 12.5 0.0 0.14 11.1 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glucosaminidase PF01832.20 EIM91722.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Aldedh PF00171.22 EIM91723.1 - 7.1e-183 608.3 0.0 8.1e-183 608.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosaminidase PF01832.20 EIM91723.1 - 0.049 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase LuxC PF05893.14 EIM91723.1 - 0.14 11.2 0.0 0.41 9.6 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Zot PF05707.12 EIM91724.1 - 0.0023 17.6 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA PF00004.29 EIM91724.1 - 0.017 15.6 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EIM91724.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EIM91724.1 - 0.093 13.0 0.2 14 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-MYND PF01753.18 EIM91725.1 - 9.5e-06 25.6 9.5 2.1e-05 24.5 9.5 1.6 1 0 0 1 1 1 1 MYND finger Transp_Tc5_C PF04236.15 EIM91725.1 - 0.066 13.6 0.6 0.15 12.4 0.6 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-HIT PF04438.16 EIM91725.1 - 0.12 12.3 8.1 0.25 11.3 8.1 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 EIM91725.1 - 1.6 9.1 4.9 3.1 8.2 4.9 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Aldedh PF00171.22 EIM91726.1 - 7.1e-180 598.4 0.3 8.1e-180 598.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM91726.1 - 0.0044 16.1 0.0 0.068 12.2 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Zot PF05707.12 EIM91727.1 - 0.00081 19.1 0.0 0.0049 16.5 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.29 EIM91727.1 - 0.0069 16.8 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM91727.1 - 0.13 12.5 0.4 10 6.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EIM91727.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase HhH-GPD PF00730.25 EIM91728.1 - 3.3e-08 34.0 0.0 5.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein F-box-like PF12937.7 EIM91730.1 - 0.025 14.5 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like Kdo PF06293.14 EIM91731.1 - 0.00055 19.3 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 EIM91733.1 - 3.4e-37 127.5 0.0 4.1e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM91733.1 - 3.5e-30 104.7 0.0 4.7e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM91733.1 - 4e-07 29.7 0.0 5.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIM91733.1 - 0.00065 19.3 0.0 0.0055 16.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIM91733.1 - 0.0011 19.0 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIM91733.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EIM91733.1 - 0.058 13.3 0.2 0.55 10.1 0.3 2.2 2 1 1 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 EIM91733.1 - 0.075 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 EIM91734.1 - 0.002 17.9 0.4 0.0093 15.8 0.1 2.3 2 1 0 2 2 2 1 F-box-like HNH_2 PF13391.6 EIM91736.1 - 0.13 12.4 0.1 0.5 10.5 0.1 1.9 1 1 0 1 1 1 0 HNH endonuclease PRIMA1 PF16101.5 EIM91736.1 - 0.4 10.7 3.7 0.7 9.9 3.7 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EIM91736.1 - 1.6 8.1 5.2 2.4 7.6 5.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEAD PF00270.29 EIM91737.1 - 1.3e-21 77.2 0.0 3.9e-11 43.0 0.0 2.7 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM91737.1 - 3.9e-12 46.5 0.0 4.4e-11 43.1 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM91737.1 - 0.033 14.2 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Glyco_transf_4 PF13439.6 EIM91737.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 BTB PF00651.31 EIM91739.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain F-box-like PF12937.7 EIM91740.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like zf-MYND PF01753.18 EIM91741.1 - 1.1e-09 38.2 13.9 1.9e-09 37.4 13.9 1.4 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 EIM91741.1 - 0.0062 17.1 0.0 17 6.1 0.0 3.7 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM91741.1 - 0.068 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM91741.1 - 0.1 13.0 0.1 1.7 9.1 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) F-box-like PF12937.7 EIM91742.1 - 0.05 13.5 3.6 0.47 10.4 0.7 2.8 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 EIM91742.1 - 0.07 13.0 1.1 0.89 9.5 0.4 2.4 1 1 1 2 2 2 0 F-box LRR_8 PF13855.6 EIM91742.1 - 0.2 11.4 1.4 3 7.7 0.0 3.3 4 0 0 4 4 4 0 Leucine rich repeat FMO-like PF00743.19 EIM91743.1 - 1.5e-18 66.5 0.2 6.3e-13 48.0 0.1 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM91743.1 - 2.7e-18 66.3 0.0 3.8e-14 52.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM91743.1 - 8.8e-15 54.7 0.0 3.5e-09 36.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIM91743.1 - 6.7e-13 48.5 0.0 3.2e-09 36.4 0.0 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM91743.1 - 4.7e-06 27.1 0.0 0.025 15.1 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EIM91743.1 - 0.00096 18.6 0.0 0.28 10.5 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EIM91743.1 - 0.0029 17.5 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EIM91743.1 - 0.0052 15.9 0.1 0.16 11.0 0.0 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIM91743.1 - 0.0062 16.7 0.0 0.057 13.7 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIM91743.1 - 0.026 13.8 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EIM91743.1 - 0.026 13.2 0.0 0.17 10.5 0.0 2.3 4 0 0 4 4 4 0 HI0933-like protein Thi4 PF01946.17 EIM91743.1 - 0.053 12.8 0.1 0.72 9.0 0.0 2.3 3 0 0 3 3 3 0 Thi4 family PKcGMP_CC PF16808.5 EIM91744.1 - 0.00078 19.2 2.8 0.00078 19.2 2.8 2.3 3 1 0 3 3 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Jnk-SapK_ap_N PF09744.9 EIM91744.1 - 0.0026 18.0 1.9 0.0062 16.8 1.9 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Cep57_MT_bd PF06657.13 EIM91744.1 - 0.005 17.2 4.8 0.79 10.2 0.9 2.6 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 PspA_IM30 PF04012.12 EIM91744.1 - 0.021 14.4 10.2 0.063 12.9 10.2 1.7 1 1 0 1 1 1 0 PspA/IM30 family Spc24 PF08286.11 EIM91744.1 - 0.025 14.8 2.4 1.9 8.8 0.3 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.7 EIM91744.1 - 0.034 14.3 5.9 0.042 14.0 1.0 2.3 2 0 0 2 2 2 0 Tropomyosin like Occludin_ELL PF07303.13 EIM91744.1 - 0.069 13.9 1.5 0.16 12.7 1.5 1.6 1 0 0 1 1 1 0 Occludin homology domain SLATT_4 PF18186.1 EIM91744.1 - 0.088 12.4 0.2 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 IL2 PF00715.17 EIM91744.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Interleukin 2 DUF4407 PF14362.6 EIM91744.1 - 0.16 11.3 2.8 0.41 9.9 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 EIM91744.1 - 0.28 11.7 4.5 5.3 7.6 4.5 2.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.9 EIM91744.1 - 0.34 11.2 3.6 3.4 8.0 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 EIM91744.1 - 0.65 10.4 5.1 0.64 10.4 1.6 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain ADIP PF11559.8 EIM91744.1 - 0.8 9.8 5.9 1.6 8.8 1.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EIM91744.1 - 1 9.9 11.8 2.1 8.8 0.2 2.7 3 0 0 3 3 2 0 Cell division protein ZapB APG6_N PF17675.1 EIM91744.1 - 2.5 8.6 9.9 5.7 7.5 9.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 EIM91744.1 - 5.6 7.1 16.6 2.1 8.5 2.3 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 EIM91744.1 - 10 6.0 9.1 12 5.8 2.1 2.5 1 1 1 2 2 2 0 Septum formation initiator USP8_interact PF08941.10 EIM91745.1 - 0.04 13.7 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 USP8 interacting Mis14 PF08641.12 EIM91745.1 - 0.044 14.1 0.5 0.1 12.9 0.5 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like DUF4533 PF15047.6 EIM91745.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) MaoC_dehydrat_N PF13452.6 EIM91745.1 - 0.085 13.0 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase DivIC PF04977.15 EIM91745.1 - 0.22 11.3 5.8 0.045 13.5 1.8 1.9 2 0 0 2 2 2 0 Septum formation initiator HalX PF08663.10 EIM91745.1 - 0.25 11.7 4.5 1 9.7 0.6 2.9 2 0 0 2 2 2 0 HalX domain DUF16 PF01519.16 EIM91745.1 - 0.26 11.8 1.5 0.49 10.9 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Csm1_N PF18504.1 EIM91745.1 - 0.29 11.5 2.6 0.33 11.3 0.5 2.3 2 0 0 2 2 1 0 Csm1 N-terminal domain Fib_alpha PF08702.10 EIM91745.1 - 0.52 10.5 5.0 0.74 10.0 1.4 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 EIM91745.1 - 0.97 9.7 6.8 0.32 11.2 2.1 2.5 2 1 0 2 2 2 0 Haemolysin XhlA TMF_DNA_bd PF12329.8 EIM91745.1 - 1.4 8.9 7.0 0.26 11.3 1.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CLZ PF16526.5 EIM91745.1 - 1.5 9.2 6.5 0.54 10.6 0.4 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2680 PF10925.8 EIM91745.1 - 1.7 8.7 3.6 5 7.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Atg14 PF10186.9 EIM91745.1 - 1.9 7.5 8.4 3.8 6.5 8.4 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EIM91745.1 - 2.8 7.2 5.9 2.7 7.3 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EIM91745.1 - 4.3 7.8 6.1 1.5 9.3 0.2 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) WD40 PF00400.32 EIM91746.1 - 2.3e-05 25.1 0.0 0.43 11.5 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Hormone_3 PF00159.18 EIM91746.1 - 0.043 13.9 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Pancreatic hormone peptide p450 PF00067.22 EIM91747.1 - 7.3e-64 216.2 0.0 8.3e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.22 EIM91748.1 - 4.1e-18 66.3 0.0 6.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 EIM91748.1 - 0.016 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 CHAT domain IU_nuc_hydro PF01156.19 EIM91749.1 - 9.7e-56 189.6 0.0 1.3e-55 189.2 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase GMC_oxred_N PF00732.19 EIM91750.1 - 1.1e-44 153.0 1.2 1.6e-25 90.1 0.2 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM91750.1 - 5.9e-10 39.8 0.0 1.5e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM91750.1 - 2.7e-05 23.4 0.7 0.0015 17.7 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 EIM91750.1 - 5e-05 23.4 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM91750.1 - 0.00013 21.7 1.1 0.00048 19.8 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIM91750.1 - 0.00026 20.1 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIM91750.1 - 0.00042 19.6 0.1 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM91750.1 - 0.00099 18.4 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EIM91750.1 - 0.0037 16.6 0.0 0.4 9.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM91750.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding F-box-like PF12937.7 EIM91751.1 - 0.00014 21.6 0.9 0.00026 20.8 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91751.1 - 0.078 12.9 0.5 0.26 11.2 0.3 1.9 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 EIM91751.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box Peptidase_C14 PF00656.22 EIM91753.1 - 6.6e-20 72.1 0.0 1.1e-19 71.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C54 PF03416.19 EIM91754.1 - 1.7e-102 342.6 0.0 2.6e-102 342.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 F-box-like PF12937.7 EIM91755.1 - 2e-05 24.4 0.6 5.2e-05 23.1 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91755.1 - 0.02 14.8 0.8 1 9.3 0.2 2.6 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 EIM91755.1 - 0.2 12.1 2.3 7.5 7.1 0.3 3.8 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) GMC_oxred_C PF05199.13 EIM91756.1 - 3.6e-11 43.8 0.1 4.3e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM91757.1 - 0.092 13.3 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase GMC_oxred_N PF00732.19 EIM91759.1 - 1.2e-39 136.5 3.7 1.5e-25 90.2 0.1 3.1 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM91759.1 - 2.1e-23 83.5 0.0 5.7e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM91759.1 - 1.5e-05 24.2 0.4 0.00016 20.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EIM91759.1 - 3.2e-05 23.7 1.4 0.00019 21.2 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM91759.1 - 0.00021 21.5 0.1 0.0011 19.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIM91759.1 - 0.00027 20.1 0.1 0.00042 19.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIM91759.1 - 0.001 18.4 0.1 0.0054 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM91759.1 - 0.0028 16.9 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EIM91759.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM91759.1 - 0.15 10.7 0.1 0.23 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Gpr1_Fun34_YaaH PF01184.19 EIM91761.1 - 4.6e-61 206.0 20.1 5.8e-61 205.7 20.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4191 PF13829.6 EIM91761.1 - 0.8 9.0 2.2 1.3 8.3 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tetraspanin PF00335.20 EIM91761.1 - 9.4 5.9 15.4 4.3 7.0 12.1 2.1 1 1 1 2 2 2 0 Tetraspanin family Gpr1_Fun34_YaaH PF01184.19 EIM91762.1 - 3.2e-66 222.9 18.9 4.1e-66 222.5 18.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Peptidase_S64 PF08192.11 EIM91763.1 - 0.0002 20.0 0.0 0.00031 19.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S64 Acetyltransf_3 PF13302.7 EIM91764.1 - 1.5e-17 64.6 0.0 1.4e-08 35.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EIM91764.1 - 0.0013 18.5 0.4 0.38 10.4 0.3 3.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM91764.1 - 0.0066 16.4 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 EIM91764.1 - 0.042 14.1 0.0 8.3 6.7 0.0 2.6 2 1 1 3 3 3 0 Acetyltransferase (GNAT) family Alpha-L-AF_C PF06964.12 EIM91767.1 - 2.1e-33 115.8 0.0 3.4e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain FMO-like PF00743.19 EIM91768.1 - 2.5e-16 59.2 0.0 1.1e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIM91768.1 - 1.6e-14 53.9 0.0 5.3e-13 48.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIM91768.1 - 3.1e-14 52.9 0.0 7.9e-05 22.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIM91768.1 - 3.3e-12 46.2 0.0 7.3e-06 25.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EIM91768.1 - 5.8e-10 39.6 0.0 3.8e-05 24.2 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM91768.1 - 7.1e-05 23.0 0.0 0.0021 18.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIM91768.1 - 0.00012 21.4 0.3 0.0017 17.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EIM91768.1 - 0.00019 20.6 0.5 0.00043 19.5 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EIM91768.1 - 0.00023 20.4 0.1 0.002 17.3 0.0 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EIM91768.1 - 0.0013 17.9 0.0 0.0032 16.6 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EIM91768.1 - 0.0015 18.0 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EIM91768.1 - 0.003 16.3 0.0 0.0084 14.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 EIM91768.1 - 0.0047 16.9 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EIM91768.1 - 0.011 15.7 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EIM91768.1 - 0.019 14.2 0.1 0.45 9.7 0.0 2.4 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 EIM91768.1 - 0.041 13.4 0.8 0.13 11.8 0.7 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EIM91768.1 - 0.042 13.2 0.1 0.069 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EIM91768.1 - 0.047 14.1 0.0 2.7 8.5 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EIM91768.1 - 0.075 12.3 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EIM91768.1 - 0.077 13.3 0.3 0.29 11.4 0.1 2.1 3 0 0 3 3 2 0 TrkA-N domain 3HCDH_N PF02737.18 EIM91768.1 - 0.078 12.9 0.0 7.4 6.4 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EIM91768.1 - 0.13 11.9 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1378 PF07125.11 EIM91768.1 - 0.18 12.0 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) HNH_2 PF13391.6 EIM91769.1 - 0.00011 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease But2 PF09792.9 EIM91770.1 - 0.0001 22.7 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 EIM91771.1 - 9.2e-14 51.7 8.8 2.7e-13 50.2 8.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3112 PF11309.8 EIM91774.1 - 0.6 9.5 5.0 0.36 10.3 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3112) DUF3328 PF11807.8 EIM91775.1 - 2.2e-18 66.9 0.1 5.9e-18 65.5 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) HNH_2 PF13391.6 EIM91777.1 - 4.5e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Mem_trans PF03547.18 EIM91778.1 - 5.4e-16 58.0 10.9 7.9e-15 54.1 10.9 2.0 1 1 0 1 1 1 1 Membrane transport protein UCH PF00443.29 EIM91779.1 - 1.1e-40 139.8 0.0 7.5e-40 137.0 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EIM91779.1 - 6.7e-27 93.6 8.3 4.1e-20 71.9 0.5 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EIM91779.1 - 2.9e-25 87.7 0.2 9.5e-12 44.6 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EIM91779.1 - 4.3e-25 87.2 3.3 4e-24 84.2 0.7 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 EIM91779.1 - 4.3e-12 46.3 0.0 4e-10 39.8 0.0 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase C1_2 PF03107.16 EIM91779.1 - 4.6 7.7 8.1 27 5.2 0.1 3.5 3 0 0 3 3 3 0 C1 domain HSP70 PF00012.20 EIM91780.1 - 7.1e-53 179.7 0.3 2.2e-35 122.0 0.0 2.6 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EIM91780.1 - 0.083 11.7 0.0 0.83 8.4 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein F-box-like PF12937.7 EIM91781.1 - 6.4e-06 26.0 0.3 6.4e-06 26.0 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EIM91782.1 - 1.1e-05 25.2 0.5 3.6e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like Kri1_C PF12936.7 EIM91782.1 - 0.22 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 KRI1-like family C-terminal AHH PF14412.6 EIM91786.1 - 9.7e-05 22.4 0.0 0.74 9.9 0.0 2.5 2 0 0 2 2 2 2 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH HNH_2 PF13391.6 EIM91786.1 - 0.0023 18.0 0.0 4.7 7.4 0.0 2.7 2 0 0 2 2 2 2 HNH endonuclease MDFI PF15316.6 EIM91786.1 - 0.0043 17.2 0.1 7.4 6.6 0.0 3.0 3 0 0 3 3 3 2 MyoD family inhibitor Ribosomal_S7 PF00177.21 EIM91786.1 - 0.021 14.5 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e TadF PF16964.5 EIM91786.1 - 0.094 12.5 0.2 17 5.1 0.0 2.2 2 0 0 2 2 2 0 Putative tight adherence pilin protein F TFIIA PF03153.13 EIM91786.1 - 3.5 7.5 5.6 22 4.9 0.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-4CXXC_R1 PF10497.9 EIM91787.1 - 1.9e-10 40.8 18.0 4.3e-10 39.7 18.0 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Tannase PF07519.11 EIM91790.1 - 4.5e-92 309.4 0.0 5.9e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase RPN7 PF10602.9 EIM91791.1 - 0.024 14.3 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 SesA PF17107.5 EIM91791.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NAP PF00956.18 EIM91794.1 - 1.7e-88 296.3 4.9 2.4e-88 295.8 4.9 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) F-box-like PF12937.7 EIM91795.1 - 8.2e-18 64.0 15.1 1.4e-05 24.9 0.2 4.8 4 0 0 4 4 4 3 F-box-like SAE2 PF08573.10 EIM91797.1 - 6.9e-21 75.4 1.7 6.9e-21 75.4 1.7 2.1 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Mcm10 PF09332.11 EIM91797.1 - 3.8 6.8 10.7 9.7 5.5 10.7 1.6 1 1 0 1 1 1 0 Mcm10 replication factor Macoilin PF09726.9 EIM91799.1 - 3 6.3 10.8 5 5.5 10.8 1.3 1 0 0 1 1 1 0 Macoilin family F-box-like PF12937.7 EIM91801.1 - 2.7e-10 40.0 0.9 7.2e-10 38.6 0.9 1.8 1 0 0 1 1 1 1 F-box-like Abhydrolase_1 PF00561.20 EIM91802.1 - 7.2e-20 71.7 0.2 2.5e-19 70.0 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM91802.1 - 1.1e-13 52.3 0.3 1.5e-13 51.9 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM91802.1 - 1.3e-08 34.4 0.0 2.2e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EIM91802.1 - 2.2e-05 24.7 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 EIM91802.1 - 0.088 12.6 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family LSM PF01423.22 EIM91803.1 - 8.3e-18 63.8 0.1 9.5e-18 63.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIM91803.1 - 7.5e-05 22.8 0.1 9e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain F-box-like PF12937.7 EIM91804.1 - 1.5e-10 40.8 0.7 4e-10 39.4 0.7 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM91804.1 - 0.56 10.7 3.4 23 5.6 0.0 5.0 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) DUF2834 PF11196.8 EIM91805.1 - 1.2e-06 28.7 21.5 0.0081 16.5 8.6 3.8 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) Zn_clus PF00172.18 EIM91806.1 - 1.3e-08 34.8 10.4 2e-08 34.2 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.26 EIM91807.1 - 3e-145 484.8 0.9 4e-145 484.4 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EIM91807.1 - 1.3e-26 93.0 0.1 2.5e-26 92.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EIM91807.1 - 4.2e-09 36.6 0.1 2.4e-08 34.1 0.1 2.5 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1421 PF07223.11 EIM91807.1 - 0.29 11.0 0.5 13 5.7 0.0 2.8 3 0 0 3 3 3 0 UBA-like domain (DUF1421) Glyco_hydro_31 PF01055.26 EIM91808.1 - 9.9e-144 479.8 2.5 1.3e-143 479.4 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EIM91808.1 - 5.3e-28 97.5 0.0 1e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EIM91808.1 - 8.3e-05 22.8 0.4 0.00075 19.8 0.1 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.26 EIM91809.1 - 4.4e-143 477.7 2.2 5.5e-143 477.3 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EIM91809.1 - 1.9e-28 99.0 0.1 3.8e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EIM91809.1 - 0.00023 21.4 0.0 0.0012 19.1 0.0 2.4 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EIM91809.1 - 0.04 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Aldolase_II PF00596.21 EIM91810.1 - 1.6e-41 142.3 0.0 2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain adh_short_C2 PF13561.6 EIM91811.1 - 2.3e-50 171.3 1.3 2.9e-50 171.0 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM91811.1 - 2.9e-35 121.5 1.3 3.8e-35 121.1 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM91811.1 - 1.7e-09 37.8 0.3 2.5e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 EIM91811.1 - 0.035 13.5 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein HMG_box PF00505.19 EIM91814.1 - 2.8e-16 59.7 2.6 4.8e-16 58.9 2.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM91814.1 - 4.3e-14 52.8 1.3 8e-14 52.0 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain Cu-oxidase PF00394.22 EIM91817.1 - 7.6e-43 146.4 0.9 1.4e-41 142.2 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM91817.1 - 3e-35 120.9 1.9 7.1e-34 116.5 0.7 2.8 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM91817.1 - 1.4e-31 109.0 3.0 5e-28 97.5 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Lactamase_B_2 PF12706.7 EIM91818.1 - 0.0056 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DDE_Tnp_4 PF13359.6 EIM91819.1 - 6.2e-21 74.7 0.0 1.8e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EIM91819.1 - 0.00086 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain PAS_3 PF08447.12 EIM91819.1 - 0.041 14.2 0.1 0.094 13.0 0.1 1.6 1 0 0 1 1 1 0 PAS fold Macoilin PF09726.9 EIM91819.1 - 0.16 10.5 2.2 0.19 10.3 2.2 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 EIM91819.1 - 0.18 11.7 3.0 0.27 11.1 3.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family RAP1 PF07218.11 EIM91819.1 - 0.36 9.0 8.9 0.47 8.7 8.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1635 PF07795.11 EIM91819.1 - 2.1 8.1 4.2 3.5 7.4 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Phage_tail_2 PF06199.11 EIM91820.1 - 0.071 13.2 0.7 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Phage tail tube protein DUF493 PF04359.14 EIM91820.1 - 0.14 12.8 0.2 0.44 11.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF493) PEMT PF04191.13 EIM91821.1 - 1.4e-32 112.2 2.8 3.7e-32 110.9 2.5 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ArAE_2 PF10334.9 EIM91822.1 - 3.7e-57 193.8 0.1 7.4e-57 192.8 0.0 1.6 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 EIM91822.1 - 9.2e-46 156.9 17.6 2.6e-38 132.3 10.3 4.1 3 1 0 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EIM91822.1 - 4e-09 36.7 17.3 4e-09 36.7 17.3 2.9 3 0 0 3 3 3 1 Fusaric acid resistance protein-like GST_C_3 PF14497.6 EIM91823.1 - 7.1e-16 58.2 0.0 2e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIM91823.1 - 2.4e-08 34.2 0.0 4.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIM91823.1 - 6.5e-05 23.1 0.0 0.00066 19.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIM91823.1 - 0.00025 21.0 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIM91823.1 - 0.00026 21.3 0.0 0.00049 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EIM91823.1 - 0.07 13.9 0.0 0.24 12.1 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 EIM91825.1 - 9.4e-08 32.3 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIM91825.1 - 0.00026 21.3 0.0 0.00044 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIM91825.1 - 0.0062 16.8 0.0 0.0092 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EIM91825.1 - 0.0085 16.8 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain PTCB-BRCT PF12738.7 EIM91827.1 - 1.5e-27 95.3 1.6 4.8e-15 55.3 0.1 5.2 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 EIM91827.1 - 2.8e-23 82.1 0.0 4.2e-07 30.3 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EIM91827.1 - 5.2e-17 62.0 0.0 0.071 13.5 0.0 6.5 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EIM91827.1 - 6.3e-15 54.9 0.0 3.8e-13 49.2 0.0 3.1 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 EIM91827.1 - 2.8e-05 24.3 0.1 0.0051 17.1 0.0 3.6 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EIM91827.1 - 0.00034 20.6 0.1 0.26 11.4 0.0 3.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain FliC PF12445.8 EIM91827.1 - 0.014 15.7 0.1 0.038 14.3 0.1 1.7 1 0 0 1 1 1 0 Flagellin protein Mpv17_PMP22 PF04117.12 EIM91828.1 - 4.3e-22 78.1 1.3 7.3e-22 77.4 1.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family V-SNARE PF05008.15 EIM91829.1 - 1.6e-21 76.5 3.6 1.6e-21 76.5 3.6 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EIM91829.1 - 3e-16 59.5 7.1 3.9e-16 59.1 4.7 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 EIM91829.1 - 0.0026 15.8 1.6 0.048 11.6 0.2 2.0 2 0 0 2 2 2 2 Prominin DUF4795 PF16043.5 EIM91829.1 - 0.017 14.8 0.4 0.017 14.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 EIM91829.1 - 0.018 14.6 6.2 0.14 11.7 5.2 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit Cep57_CLD PF14073.6 EIM91829.1 - 0.02 14.9 1.7 0.02 14.9 1.7 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Sec20 PF03908.13 EIM91829.1 - 0.027 14.4 0.8 0.052 13.5 0.2 1.8 2 0 0 2 2 2 0 Sec20 DUF745 PF05335.13 EIM91829.1 - 0.048 13.4 4.2 3 7.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF3225 PF11533.8 EIM91829.1 - 0.083 12.6 0.8 0.14 11.9 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) DUF241 PF03087.14 EIM91829.1 - 3.5 7.4 7.7 0.68 9.7 0.5 2.3 1 1 1 3 3 3 0 Arabidopsis protein of unknown function Prefoldin_2 PF01920.20 EIM91830.1 - 3.3e-21 75.2 12.8 7.5e-21 74.1 12.8 1.6 1 1 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 EIM91830.1 - 0.059 13.8 6.8 0.066 13.7 1.8 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin_3 PF13758.6 EIM91830.1 - 0.071 13.2 3.5 0.097 12.7 3.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit YabA PF06156.13 EIM91830.1 - 0.18 12.5 11.3 0.49 11.0 4.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA BRE1 PF08647.11 EIM91830.1 - 0.22 11.6 12.1 0.074 13.1 2.6 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase End3 PF12761.7 EIM91830.1 - 0.34 11.1 9.4 0.63 10.2 9.4 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Atg14 PF10186.9 EIM91830.1 - 0.41 9.7 7.4 0.62 9.1 7.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EIM91830.1 - 1.5 8.9 12.8 0.23 11.5 5.6 2.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 EIM91830.1 - 1.5 8.6 9.8 1.2 9.0 4.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.13 EIM91830.1 - 2 8.8 15.4 28 5.1 15.4 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF641 PF04859.12 EIM91830.1 - 3.8 7.9 10.2 16 5.8 10.1 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Prefoldin PF02996.17 EIM91830.1 - 4.4 7.3 11.7 2.7 7.9 5.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit F-box-like PF12937.7 EIM91831.1 - 1.9e-08 34.1 3.0 8.9e-08 31.9 3.0 2.3 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIM91832.1 - 2e-07 30.8 8.3 1.2e-06 28.3 8.3 2.3 1 1 0 1 1 1 1 F-box-like BTB PF00651.31 EIM91833.1 - 1.6e-07 31.5 0.0 3.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 EIM91834.1 - 5.6e-08 32.6 0.0 1.5e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91834.1 - 0.44 10.5 1.6 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EIM91835.1 - 4.2e-16 58.6 10.7 7.1e-08 32.2 1.8 2.7 2 0 0 2 2 2 2 F-box-like LRR_4 PF12799.7 EIM91835.1 - 0.035 14.5 3.0 25 5.4 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Oxidored_FMN PF00724.20 EIM91836.1 - 3.4e-32 112.1 0.0 4.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Granulin PF00396.18 EIM91839.1 - 0.052 13.9 2.0 0.089 13.1 2.0 1.3 1 0 0 1 1 1 0 Granulin Fasciclin PF02469.22 EIM91840.1 - 9.3e-32 109.9 1.3 1e-19 71.0 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain FKBP_C PF00254.28 EIM91841.1 - 8.6e-19 67.7 0.0 2.5e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dabb PF07876.12 EIM91842.1 - 0.12 13.0 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain RabGAP-TBC PF00566.18 EIM91844.1 - 1.9e-29 102.9 0.0 3.1e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.17 EIM91844.1 - 0.00074 19.1 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BTB PF00651.31 EIM91845.1 - 0.002 18.3 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fer4_21 PF14697.6 EIM91845.1 - 0.12 12.5 3.3 0.92 9.7 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain preATP-grasp_3 PF18301.1 EIM91846.1 - 0.12 12.7 0.1 12 6.3 0.1 2.9 2 1 1 3 3 3 0 pre ATP-grasp 3 domain zf-MYND PF01753.18 EIM91847.1 - 3e-09 36.8 14.2 6.2e-09 35.8 14.2 1.5 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 EIM91847.1 - 1.5 6.5 2.9 2 6.2 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 EIM91847.1 - 6.6 7.1 10.6 13 6.1 10.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 EIM91848.1 - 4.3e-07 29.7 2.3 1.5e-06 28.0 2.3 2.0 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 EIM91849.1 - 3.6e-72 242.9 0.0 2.5e-70 236.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91849.1 - 5.5e-38 130.7 0.0 8.8e-34 116.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM91849.1 - 2.7e-07 29.7 0.3 6.5e-07 28.5 0.3 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIM91849.1 - 2.6e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM91849.1 - 0.006 16.0 0.1 0.021 14.2 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EIM91849.1 - 0.016 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Macoilin PF09726.9 EIM91849.1 - 0.074 11.6 2.1 0.14 10.7 2.1 1.4 1 0 0 1 1 1 0 Macoilin family DUF2621 PF11084.8 EIM91849.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) F-box-like PF12937.7 EIM91850.1 - 1.5e-07 31.2 1.8 4.1e-07 29.8 1.8 1.7 1 0 0 1 1 1 1 F-box-like RIO1 PF01163.22 EIM91851.1 - 0.00024 20.7 0.1 0.0006 19.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EIM91851.1 - 0.00055 19.4 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 EIM91851.1 - 0.0024 17.5 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 EIM91851.1 - 0.0039 17.1 0.3 0.0074 16.2 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EIM91851.1 - 0.0069 15.7 0.1 0.017 14.4 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM91851.1 - 0.026 13.3 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase 2-oxoacid_dh PF00198.23 EIM91852.1 - 5.7e-50 169.9 0.0 2.3e-49 168.0 0.0 1.8 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EIM91852.1 - 1.3e-18 66.6 0.8 3.2e-18 65.3 0.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EIM91852.1 - 4.6e-12 46.1 0.2 1.9e-11 44.1 0.2 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EIM91852.1 - 0.00032 20.4 1.0 0.00074 19.3 0.5 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EIM91852.1 - 0.055 14.2 0.1 0.14 12.8 0.1 1.7 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_D23 PF16576.5 EIM91852.1 - 0.15 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Abhydrolase_1 PF00561.20 EIM91853.1 - 3.1e-39 135.2 0.0 7.7e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM91853.1 - 0.057 14.0 9.0 0.1 13.2 9.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DHC_N1 PF08385.12 EIM91855.1 - 1.6e-128 429.9 10.6 2e-127 426.2 7.0 2.4 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 Cullin PF00888.22 EIM91856.1 - 1.9e-136 456.2 0.0 2.3e-136 455.9 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EIM91856.1 - 2.5e-24 85.1 1.0 1.2e-23 82.8 1.0 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2175 PF09943.9 EIM91856.1 - 0.19 12.0 0.3 0.72 10.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) CdiI_2 PF18593.1 EIM91856.1 - 0.24 12.1 1.3 0.62 10.8 0.2 2.3 2 0 0 2 2 2 0 CdiI immunity protein adh_short PF00106.25 EIM91857.1 - 3.6e-21 75.5 0.2 9.6e-21 74.1 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM91857.1 - 8.6e-14 51.7 0.2 6.3e-12 45.5 0.5 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM91857.1 - 5.9e-08 32.8 0.2 5.9e-08 32.8 0.2 1.8 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 EIM91857.1 - 0.078 12.8 0.4 0.26 11.1 0.2 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 EIM91857.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EIM91857.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase aGPT-Pplase1 PF18723.1 EIM91858.1 - 4.9e-87 291.9 0.0 6.6e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 DAAD PF18752.1 EIM91858.1 - 0.23 11.3 1.9 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase Ribonucleas_3_3 PF14622.6 EIM91859.1 - 1e-16 61.3 0.0 1.3e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIM91859.1 - 0.021 15.4 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease III domain Parvo_coat PF00740.18 EIM91859.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF3328 PF11807.8 EIM91860.1 - 5.4e-16 59.0 1.0 7.7e-16 58.5 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.9 EIM91861.1 - 3.9e-05 24.1 0.0 6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 EIM91862.1 - 0.024 14.4 0.2 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) MFS_1 PF07690.16 EIM91863.1 - 9.9e-43 146.4 58.0 2.9e-42 144.9 57.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM91863.1 - 2.1e-11 43.4 13.2 2.1e-11 43.4 13.2 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 EIM91866.1 - 4.5e-22 78.8 0.0 6.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIM91866.1 - 0.019 15.2 0.9 0.052 13.8 0.9 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EIM91866.1 - 0.043 12.7 0.7 2.3 6.9 0.6 2.4 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EIM91866.1 - 0.064 12.5 0.5 0.18 11.0 0.7 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM91866.1 - 0.066 12.4 0.4 0.13 11.5 0.4 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 EIM91866.1 - 0.086 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 EIM91866.1 - 0.58 9.7 2.9 0.95 9.0 2.9 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF3328 PF11807.8 EIM91867.1 - 1.1e-13 51.5 1.5 1.3e-13 51.3 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) K_oxygenase PF13434.6 EIM91868.1 - 2.5e-15 56.5 0.0 7e-11 41.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIM91868.1 - 2.7e-15 56.4 0.0 3.3e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIM91868.1 - 3e-10 40.2 0.9 0.13 11.8 0.0 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIM91868.1 - 5.7e-10 38.9 0.0 0.006 15.9 0.0 3.8 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIM91868.1 - 1.9e-09 37.6 0.3 6.9e-06 26.2 0.0 3.0 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIM91868.1 - 5e-09 36.3 0.3 0.075 13.0 0.0 4.2 4 0 0 4 4 4 3 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EIM91868.1 - 1.2e-08 34.7 0.0 0.061 12.6 0.0 3.3 2 1 1 3 3 3 3 Flavin containing amine oxidoreductase FMO-like PF00743.19 EIM91868.1 - 1.8e-08 33.3 0.0 1.6e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 EIM91868.1 - 7.8e-07 28.6 0.2 0.00062 19.1 0.0 2.5 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 EIM91868.1 - 3.3e-06 26.1 0.3 0.77 8.4 0.0 4.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 EIM91868.1 - 0.0001 21.5 1.4 0.25 10.4 0.1 3.7 4 0 0 4 4 4 1 FAD binding domain Pyr_redox PF00070.27 EIM91868.1 - 0.00021 21.8 3.5 0.0016 19.0 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIM91868.1 - 0.0019 17.4 2.3 2.5 7.1 0.0 3.3 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EIM91868.1 - 0.0022 17.3 0.9 0.12 11.6 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 EIM91868.1 - 0.0092 16.4 0.0 0.54 10.7 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 EIM91868.1 - 0.029 13.7 0.0 4.2 6.6 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EIM91868.1 - 0.048 13.7 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EIM91868.1 - 0.083 13.5 0.4 10 6.8 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EIM91868.1 - 0.15 12.0 0.3 8.7 6.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mqo PF06039.15 EIM91868.1 - 0.21 10.1 0.0 0.36 9.3 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) ApbA PF02558.16 EIM91868.1 - 0.3 10.7 0.7 5.3 6.7 0.2 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_hydr_30_2 PF14587.6 EIM91869.1 - 4.2e-24 85.8 0.0 6.8e-22 78.6 0.0 2.1 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Thaumatin PF00314.17 EIM91870.1 - 2.6e-23 82.8 0.3 2.6e-23 82.8 0.3 1.9 1 1 1 2 2 2 2 Thaumatin family Sulfatase PF00884.23 EIM91872.1 - 8.3e-50 169.9 0.1 1.1e-49 169.6 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EIM91872.1 - 0.00031 20.4 0.9 0.031 13.9 0.0 2.8 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF21 PF01595.20 EIM91873.1 - 7.1e-28 97.5 0.1 1.1e-27 96.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EIM91873.1 - 3.6e-05 24.1 0.1 0.22 12.0 0.0 2.9 3 0 0 3 3 3 2 CBS domain Virul_fac_BrkB PF03631.15 EIM91873.1 - 0.22 11.1 3.3 0.38 10.3 3.3 1.4 1 0 0 1 1 1 0 Virulence factor BrkB tRNA_U5-meth_tr PF05958.11 EIM91874.1 - 1.5e-15 57.1 0.0 4.9e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EIM91874.1 - 2.3e-07 30.5 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EIM91874.1 - 0.00017 22.2 0.0 0.00034 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM91874.1 - 0.0002 21.2 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM91874.1 - 0.00065 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EIM91874.1 - 0.016 15.8 0.0 0.036 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EIM91874.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 EIM91874.1 - 0.047 13.5 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S10 PF00450.22 EIM91875.1 - 3.2e-109 366.1 0.0 3.9e-109 365.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EIM91875.1 - 0.12 12.9 0.1 1.2 9.7 0.1 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ank_2 PF12796.7 EIM91876.1 - 0.0024 18.4 0.0 0.0046 17.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIM91876.1 - 0.021 15.4 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIM91876.1 - 0.022 15.3 0.0 0.092 13.4 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat RdRP_4 PF02123.16 EIM91877.1 - 0.0094 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Viral RNA-directed RNA-polymerase Sulfatase PF00884.23 EIM91878.1 - 8e-52 176.5 0.2 1.1e-51 176.1 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EIM91878.1 - 0.011 15.3 0.4 0.022 14.4 0.0 1.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Cu-oxidase PF00394.22 EIM91879.1 - 7.8e-40 136.6 0.6 3.4e-35 121.5 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM91879.1 - 2.5e-34 117.9 8.5 1.1e-33 115.9 0.5 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM91879.1 - 3.3e-32 111.0 4.3 2.6e-31 108.1 0.1 3.9 4 1 0 5 5 5 1 Multicopper oxidase ATP11 PF06644.11 EIM91880.1 - 1.7e-67 228.1 0.0 1.9e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein PI3K_C2 PF00792.24 EIM91880.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Rtf2 PF04641.12 EIM91881.1 - 1.7e-73 247.2 3.7 2.4e-73 246.7 3.7 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EIM91881.1 - 0.00076 19.3 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EIM91881.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Med19 PF10278.9 EIM91881.1 - 0.2 11.6 6.1 0.49 10.3 4.6 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF2058 PF09831.9 EIM91881.1 - 6.4 6.9 9.0 6.2 6.9 7.6 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Med21 PF11221.8 EIM91882.1 - 6.3e-28 97.8 7.4 8.5e-28 97.4 7.4 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF4094 PF13334.6 EIM91882.1 - 0.056 13.9 0.5 0.18 12.3 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) UME PF08064.13 EIM91882.1 - 0.068 13.1 0.3 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 UME (NUC010) domain DUF4407 PF14362.6 EIM91882.1 - 0.17 11.2 3.3 0.2 11.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HalX PF08663.10 EIM91882.1 - 0.37 11.1 4.0 5.8 7.3 0.8 2.7 2 1 0 2 2 2 0 HalX domain Cep57_MT_bd PF06657.13 EIM91882.1 - 0.52 10.8 5.4 2.3 8.7 0.7 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 PS_Dcarbxylase PF02666.15 EIM91883.1 - 6.7e-70 234.7 0.0 4.8e-52 176.4 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylserine decarboxylase Med3 PF11593.8 EIM91883.1 - 2.2 7.4 4.8 3 6.9 4.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NAD_binding_10 PF13460.6 EIM91884.1 - 2.9e-23 82.7 0.1 4.7e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EIM91884.1 - 0.0015 18.1 0.0 0.0066 16.0 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family IPK PF03770.16 EIM91885.1 - 7.3e-42 143.5 0.0 5.3e-24 85.2 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase CENP-B_dimeris PF09026.10 EIM91885.1 - 0.017 15.5 7.2 0.037 14.4 7.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EIM91885.1 - 0.77 10.0 8.2 0.059 13.6 1.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 EIM91885.1 - 1.4 8.6 4.7 0.45 10.2 1.2 1.8 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 EIM91885.1 - 1.8 6.6 7.8 2.7 6.0 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 EIM91885.1 - 3.1 5.8 6.7 1.7 6.6 2.0 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Aminotran_4 PF01063.19 EIM91886.1 - 7.5e-27 94.6 0.0 2.1e-26 93.2 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV DUF3328 PF11807.8 EIM91889.1 - 5e-22 78.8 0.2 7e-22 78.3 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF5367 PF17329.2 EIM91890.1 - 0.15 12.2 7.7 0.094 12.9 3.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF2070 PF09843.9 EIM91890.1 - 7 4.8 15.1 9.3 4.4 15.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Methyltransf_23 PF13489.6 EIM91891.1 - 2e-07 31.0 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIM91891.1 - 5.2e-07 30.3 0.0 9.1e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIM91891.1 - 4e-06 27.5 0.0 9.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM91891.1 - 2.1e-05 25.1 0.0 0.00015 22.4 0.0 2.4 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIM91891.1 - 0.0023 17.7 0.0 0.041 13.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EIM91891.1 - 0.069 12.3 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 EIM91891.1 - 0.15 11.3 0.0 0.35 10.2 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAM2 PF07145.15 EIM91892.1 - 0.17 11.6 10.9 0.066 12.9 0.4 3.4 3 0 0 3 3 3 0 Ataxin-2 C-terminal region DEAD PF00270.29 EIM91893.1 - 4.2e-49 166.7 0.0 6.2e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM91893.1 - 6.2e-29 100.6 0.0 1.8e-27 95.9 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM91893.1 - 2e-07 31.2 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EIM91893.1 - 0.00078 18.9 0.3 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 EIM91893.1 - 0.04 12.7 0.0 0.84 8.3 0.0 2.5 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cytochrom_C552 PF02335.15 EIM91894.1 - 0.25 10.2 6.5 0.28 10.0 6.5 1.0 1 0 0 1 1 1 0 Cytochrome c552 LEA_4 PF02987.16 EIM91894.1 - 3 8.0 21.7 0.089 12.9 13.9 2.4 2 1 0 2 2 2 0 Late embryogenesis abundant protein DUF1863 PF08937.11 EIM91895.1 - 0.039 14.3 0.0 0.05 13.9 0.0 1.3 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Med13_C PF06333.12 EIM91896.1 - 0.018 14.4 2.5 0.021 14.1 2.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain IBR PF01485.21 EIM91898.1 - 7.6e-17 61.3 20.4 5.1e-10 39.4 4.4 3.9 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain Oxysterol_BP PF01237.18 EIM91899.1 - 6.3e-87 291.8 0.0 3.9e-85 285.9 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein UPF0052 PF01933.18 EIM91900.1 - 2.1e-45 155.2 0.0 2.8e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Ras PF00071.22 EIM91902.1 - 3.3e-64 215.4 0.0 3.8e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM91902.1 - 5.8e-34 116.9 0.1 8.8e-34 116.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM91902.1 - 1.5e-14 53.8 0.1 1.9e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIM91902.1 - 7.2e-06 25.7 0.0 1.7e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EIM91902.1 - 5.5e-05 22.6 0.0 6.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EIM91902.1 - 8.3e-05 22.6 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EIM91902.1 - 8.4e-05 22.6 0.0 0.00024 21.1 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM91902.1 - 0.012 15.2 0.0 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 EIM91902.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EIM91902.1 - 0.043 13.6 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 EIM91902.1 - 0.067 12.6 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EIM91902.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 EIM91902.1 - 0.085 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin MCM PF00493.23 EIM91902.1 - 0.13 11.3 0.0 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA PF00004.29 EIM91902.1 - 0.14 12.6 0.0 0.68 10.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 EIM91903.1 - 5.4e-06 26.1 0.0 0.052 13.4 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EIM91903.1 - 5.8e-06 25.9 0.0 0.0012 18.3 0.0 3.0 2 2 1 3 3 3 1 UvrD-like helicase C-terminal domain TPR_1 PF00515.28 EIM91903.1 - 0.011 15.5 6.6 0.56 10.1 0.3 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 EIM91903.1 - 0.027 14.0 0.1 1.5 8.2 0.1 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TPR_2 PF07719.17 EIM91903.1 - 0.032 14.3 10.4 0.32 11.2 0.7 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 EIM91903.1 - 0.083 13.2 1.9 1.8 8.8 0.0 3.7 4 1 1 5 5 5 0 AAA domain AAA_19 PF13245.6 EIM91903.1 - 0.1 12.9 0.0 0.91 9.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain TPR_8 PF13181.6 EIM91903.1 - 1.1 9.6 6.4 12 6.4 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Actin PF00022.19 EIM91906.1 - 1.6e-42 145.6 0.0 1.7e-22 79.6 0.0 2.2 2 0 0 2 2 2 2 Actin Plasmod_MYXSPDY PF07981.11 EIM91906.1 - 0.32 11.0 1.8 35 4.6 0.0 3.2 3 0 0 3 3 3 0 Plasmodium repeat_MYXSPDY UvrD_C PF13361.6 EIM91907.1 - 3e-10 40.0 0.0 4.2e-08 33.0 0.0 3.4 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EIM91907.1 - 2.5e-06 27.9 0.0 1.4e-05 25.4 0.0 2.4 2 1 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.6 EIM91907.1 - 6.9e-06 25.8 0.0 0.0033 17.2 0.0 2.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EIM91907.1 - 8.7e-06 25.5 5.1 1.8e-05 24.5 0.0 2.9 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EIM91907.1 - 0.0014 18.7 0.0 0.0045 17.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_12 PF13087.6 EIM91907.1 - 0.0019 17.9 0.1 0.0077 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.17 EIM91907.1 - 0.0032 17.5 5.4 1.3 9.3 0.0 4.6 3 2 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 EIM91907.1 - 0.004 17.4 2.0 0.12 12.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EIM91907.1 - 0.0066 16.2 0.0 0.5 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EIM91907.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase TPR_7 PF13176.6 EIM91907.1 - 0.11 12.6 0.9 42 4.5 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIM91907.1 - 0.18 11.7 1.6 32 4.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_11 PF13086.6 EIM91907.1 - 0.44 10.3 3.7 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain SesA PF17107.5 EIM91907.1 - 0.64 10.2 2.6 4.2 7.6 2.5 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Syntaxin_2 PF14523.6 EIM91907.1 - 4.1 7.8 6.3 42 4.6 5.2 3.0 1 1 1 2 2 2 0 Syntaxin-like protein ABC_tran PF00005.27 EIM91908.1 - 7.1e-27 94.6 0.0 2.8e-26 92.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIM91908.1 - 1.6e-09 38.1 0.6 0.00041 20.3 0.1 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM91908.1 - 4.5e-08 33.2 0.0 4.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EIM91908.1 - 1.9e-07 30.8 0.0 5.1e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIM91908.1 - 0.00069 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EIM91908.1 - 0.0011 19.6 0.1 0.003 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIM91908.1 - 0.0052 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EIM91908.1 - 0.0084 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_27 PF13514.6 EIM91908.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EIM91908.1 - 0.039 13.1 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 EIM91908.1 - 0.04 14.2 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EIM91908.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 EIM91908.1 - 0.067 13.6 0.1 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EIM91908.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Nic96 PF04097.14 EIM91909.1 - 4.7e-144 481.2 0.0 6.3e-144 480.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 FliG_C PF01706.16 EIM91909.1 - 0.14 12.3 0.1 0.43 10.8 0.1 1.8 1 0 0 1 1 1 0 FliG C-terminal domain Filament PF00038.21 EIM91910.1 - 0.017 14.7 2.1 0.025 14.1 2.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein Tup_N PF08581.10 EIM91910.1 - 0.037 14.3 0.4 0.037 14.3 0.4 1.6 2 0 0 2 2 2 0 Tup N-terminal Golgin_A5 PF09787.9 EIM91910.1 - 0.12 11.8 3.4 0.18 11.2 3.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 APH PF01636.23 EIM91911.1 - 2.3e-18 67.0 0.0 2.2e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIM91911.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EIM91911.1 - 0.1 12.2 0.1 2 8.0 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EIM91911.1 - 0.11 11.9 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EIM91911.1 - 0.11 11.8 0.0 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain DTHCT PF08070.11 EIM91913.1 - 0.007 17.1 66.3 0.54 11.0 14.9 4.5 1 1 3 4 4 4 4 DTHCT (NUC029) region DNA_topoisoIV PF00521.20 EIM91914.1 - 3.8e-129 431.3 0.2 6e-129 430.6 0.2 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EIM91914.1 - 4.3e-47 159.6 0.2 4.3e-47 159.6 0.2 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EIM91914.1 - 3.1e-27 95.2 2.1 6.7e-27 94.1 2.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EIM91914.1 - 3.9e-12 46.7 0.0 8.2e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EIM91914.1 - 1.2e-08 35.1 0.0 4.6e-08 33.2 0.0 2.1 1 0 0 1 1 1 1 Toprim domain UvrA_inter PF17760.1 EIM91914.1 - 0.14 12.3 0.9 2.6 8.2 0.0 3.2 3 0 0 3 3 3 0 UvrA interaction domain HNH_2 PF13391.6 EIM91915.1 - 1.9e-07 31.1 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF515 PF04415.12 EIM91916.1 - 9.1 4.6 5.8 9.7 4.5 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HNH_2 PF13391.6 EIM91917.1 - 2.1e-12 47.0 0.9 4.3e-12 46.0 0.9 1.6 1 0 0 1 1 1 1 HNH endonuclease ABC_tran PF00005.27 EIM91918.1 - 4.9e-45 153.4 0.6 1.1e-21 77.7 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EIM91918.1 - 3.8e-23 81.3 5.5 3.8e-23 81.3 5.5 2.9 2 1 1 3 3 1 1 ABC transporter AAA_21 PF13304.6 EIM91918.1 - 1.1e-15 58.3 15.0 0.0025 17.7 0.5 4.8 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIM91918.1 - 2.6e-08 33.6 2.2 0.023 14.1 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EIM91918.1 - 6.4e-08 32.7 0.3 0.0048 17.0 0.3 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EIM91918.1 - 3.2e-07 30.0 0.3 0.013 15.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MeaB PF03308.16 EIM91918.1 - 1.1e-06 27.8 0.1 0.00097 18.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EIM91918.1 - 3.7e-06 27.0 2.1 0.06 13.2 0.1 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 EIM91918.1 - 9.7e-06 26.1 0.2 0.18 12.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EIM91918.1 - 1.5e-05 25.3 0.0 0.099 12.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EIM91918.1 - 3.3e-05 24.4 1.8 0.6 10.7 0.0 4.3 5 0 0 5 5 4 2 AAA domain NACHT PF05729.12 EIM91918.1 - 3.9e-05 23.6 0.1 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EIM91918.1 - 4e-05 23.9 0.1 0.36 11.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EIM91918.1 - 0.00081 19.2 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EIM91918.1 - 0.0016 18.5 0.9 0.82 9.7 0.1 3.5 3 1 0 3 3 3 1 Dynamin family AAA_33 PF13671.6 EIM91918.1 - 0.0027 17.9 0.7 2.3 8.4 0.1 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EIM91918.1 - 0.0036 17.7 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 EIM91918.1 - 0.0038 17.8 0.1 0.02 15.4 0.0 4.6 5 0 0 5 5 5 2 AAA domain Roc PF08477.13 EIM91918.1 - 0.0085 16.3 0.0 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EIM91918.1 - 0.0095 15.7 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EIM91918.1 - 0.011 15.7 0.1 3.1 7.7 0.1 2.6 2 0 0 2 2 2 0 NTPase MukB_hinge PF16330.5 EIM91918.1 - 0.011 15.5 0.3 0.011 15.5 0.3 2.2 3 0 0 3 3 2 0 MukB hinge domain FlxA PF14282.6 EIM91918.1 - 0.012 15.5 4.5 8.7 6.4 0.0 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF815 PF05673.13 EIM91918.1 - 0.016 14.4 0.0 0.61 9.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 EIM91918.1 - 0.018 15.5 0.0 8.4 6.8 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIM91918.1 - 0.018 14.6 0.0 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 EIM91918.1 - 0.018 15.0 0.1 12 6.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIM91918.1 - 0.023 13.9 0.1 4.9 6.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EIM91918.1 - 0.028 14.0 0.2 4.7 6.7 0.0 2.9 4 0 0 4 4 2 0 AAA domain DUF87 PF01935.17 EIM91918.1 - 0.035 14.2 0.0 0.035 14.2 0.0 3.4 4 1 0 4 4 2 0 Helicase HerA, central domain GBP_repeat PF02526.14 EIM91918.1 - 0.037 13.7 0.1 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 Glycophorin-binding protein ATP-synt_ab PF00006.25 EIM91918.1 - 0.056 13.1 0.4 4.8 6.8 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 EIM91918.1 - 0.067 12.8 0.1 15 5.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EIM91918.1 - 0.068 13.2 0.5 6 6.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EIM91918.1 - 0.077 12.3 0.4 0.28 10.4 0.2 2.0 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 EIM91918.1 - 0.081 12.8 0.3 4.5 7.1 0.0 3.0 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 MRP-S31 PF15433.6 EIM91918.1 - 0.18 11.5 6.8 0.35 10.5 6.8 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 AAA_15 PF13175.6 EIM91918.1 - 0.2 11.3 14.4 0.36 10.5 0.4 4.0 5 0 0 5 5 5 0 AAA ATPase domain DOT1 PF08123.13 EIM91919.1 - 1.9e-60 203.9 0.0 2.3e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EIM91919.1 - 0.019 15.6 0.0 0.039 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EIM91919.1 - 0.043 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 2OG-FeII_Oxy_3 PF13640.6 EIM91920.1 - 2.5e-09 37.9 0.1 8.9e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pinin_SDK_N PF04697.13 EIM91921.1 - 0.013 16.1 2.3 0.028 15.0 2.3 1.7 1 1 0 1 1 1 0 pinin/SDK conserved region F-box-like PF12937.7 EIM91923.1 - 9.8e-06 25.4 0.0 2.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91923.1 - 5.4e-05 23.0 0.2 0.00024 20.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EIM91923.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box AP_endonuc_2 PF01261.24 EIM91924.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DNA_methylase PF00145.17 EIM91925.1 - 1e-28 100.6 0.0 4e-28 98.7 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase eIF-5_eIF-2B PF01873.17 EIM91926.1 - 2.2e-40 137.2 0.0 3.9e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EIM91926.1 - 5.4e-23 80.9 0.6 4.7e-22 77.9 0.2 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Thiolase_N PF00108.23 EIM91927.1 - 4.7e-19 68.8 0.0 6.4e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIM91927.1 - 2.4e-06 27.2 0.0 2.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EIM91927.1 - 3.2e-05 23.6 1.7 0.17 11.4 0.2 3.0 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EIM91927.1 - 0.001 18.9 0.0 0.064 13.1 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4238 PF14022.6 EIM91928.1 - 2.3e-19 70.0 0.0 3.2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF4238 PF14022.6 EIM91929.1 - 2.7e-13 50.1 0.0 3.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.23 EIM91931.1 - 0.00096 19.1 0.1 0.0028 17.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIM91931.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EIM91931.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain F-box-like PF12937.7 EIM91932.1 - 4e-06 26.6 0.0 1.7e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91932.1 - 3.3e-05 23.6 0.8 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 1 F-box domain Zn_Tnp_IS91 PF14319.6 EIM91932.1 - 0.0091 16.0 0.7 0.0091 16.0 0.7 2.7 3 0 0 3 3 3 1 Transposase zinc-binding domain A_thal_3526 PF09713.10 EIM91932.1 - 0.099 12.9 0.2 3.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) Nudix_N_2 PF14803.6 EIM91932.1 - 7.3 6.6 8.9 23 5.0 5.5 2.9 2 0 0 2 2 2 0 Nudix N-terminal PHD PF00628.29 EIM91933.1 - 1.5e-10 40.8 8.2 2.4e-10 40.1 8.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIM91933.1 - 2.4e-05 23.8 6.1 4.2e-05 23.0 6.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EIM91933.1 - 0.027 14.1 1.3 0.056 13.1 1.3 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-CW PF07496.15 EIM91933.1 - 0.061 13.4 3.4 0.13 12.3 3.4 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger C1_1 PF00130.22 EIM91933.1 - 0.66 9.9 2.6 1.5 8.7 2.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EIM91933.1 - 1.2 9.1 4.2 2.6 8.1 4.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HATPase_c_3 PF13589.6 EIM91935.1 - 0.00023 21.0 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAH PF02671.21 EIM91935.1 - 0.00038 20.5 1.5 0.01 16.0 0.1 3.3 3 0 0 3 3 3 1 Paired amphipathic helix repeat DUF3883 PF13020.6 EIM91935.1 - 0.0018 18.3 0.0 0.0051 16.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Ndc1_Nup PF09531.10 EIM91935.1 - 2.4 6.8 7.1 3.7 6.1 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F-box PF00646.33 EIM91936.1 - 7.7e-05 22.5 3.0 7.7e-05 22.5 3.0 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EIM91936.1 - 0.0084 16.0 0.2 0.026 14.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like DUF3883 PF13020.6 EIM91937.1 - 0.00027 20.9 0.0 0.001 19.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) FYVE PF01363.21 EIM91939.1 - 1.1e-18 67.2 3.8 1.9e-18 66.3 3.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF3646 PF12362.8 EIM91939.1 - 0.14 12.5 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Transposase_21 PF02992.14 EIM91940.1 - 5.7e-07 29.0 0.1 3.5e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 EIM91940.1 - 0.0036 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) GIT_CC PF16559.5 EIM91941.1 - 0.01 15.6 0.3 0.022 14.6 0.3 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TolA_bind_tri PF16331.5 EIM91941.1 - 0.088 12.9 0.3 0.17 12.0 0.3 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation HAUS5 PF14817.6 EIM91943.1 - 0.088 11.6 0.7 0.13 11.0 0.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 F-box PF00646.33 EIM91944.1 - 9.4e-05 22.2 2.3 9.4e-05 22.2 2.3 3.0 3 1 0 3 3 3 1 F-box domain F-box-like PF12937.7 EIM91944.1 - 0.0025 17.7 0.1 0.009 15.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like Bestrophin PF01062.21 EIM91945.1 - 6.8e-34 117.6 0.7 6.3e-19 68.5 0.0 2.4 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel MAP65_ASE1 PF03999.12 EIM91945.1 - 0.028 13.1 4.0 0.042 12.6 4.0 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) CiPC PF15800.5 EIM91945.1 - 0.073 12.8 20.8 0.06 13.1 19.0 1.6 1 1 1 2 2 2 0 Clock interacting protein circadian Nucleo_P87 PF07267.11 EIM91945.1 - 0.085 11.7 1.1 0.12 11.2 1.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4229 PF14012.6 EIM91945.1 - 0.26 11.4 1.0 0.6 10.2 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) SPX PF03105.19 EIM91945.1 - 0.51 10.2 10.8 0.88 9.4 10.8 1.3 1 0 0 1 1 1 0 SPX domain CHAT PF12770.7 EIM91947.1 - 8.1e-22 78.0 0.0 1.6e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EIM91947.1 - 2.7e-09 36.6 5.2 0.0041 17.0 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EIM91947.1 - 0.00014 22.1 3.0 0.065 13.5 0.2 4.8 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIM91947.1 - 0.09 12.9 0.7 67 4.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Bestrophin PF01062.21 EIM91948.1 - 4.2e-09 36.2 1.0 6.4e-09 35.6 0.1 1.6 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel CiPC PF15800.5 EIM91948.1 - 7.9 6.1 21.9 9.8 5.8 18.5 2.1 1 1 1 2 2 2 0 Clock interacting protein circadian SET PF00856.28 EIM91949.1 - 3.9e-14 53.4 0.0 6.4e-13 49.4 0.0 2.6 1 1 0 1 1 1 1 SET domain adh_short_C2 PF13561.6 EIM91950.1 - 5.4e-53 179.9 0.7 8e-53 179.4 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM91950.1 - 1.3e-39 135.7 0.5 1.3e-39 135.7 0.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EIM91950.1 - 8.6e-14 51.8 0.5 1.3e-13 51.2 0.5 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIM91950.1 - 0.018 14.2 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EIM91950.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HA2 PF04408.23 EIM91951.1 - 7e-24 84.2 0.2 7.1e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIM91951.1 - 1.1e-15 57.7 0.0 2.9e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIM91951.1 - 3.7e-08 33.7 0.4 1.2e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain F-box PF00646.33 EIM91953.1 - 6.5e-07 29.1 3.6 3.4e-06 26.8 1.9 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM91953.1 - 2.1e-05 24.3 0.3 6.2e-05 22.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like LSM PF01423.22 EIM91954.1 - 1.3e-06 28.0 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIM91954.1 - 0.0012 19.0 0.0 0.0013 18.8 0.0 1.0 1 0 0 1 1 1 1 Ataxin 2 SM domain DNA_pol3_beta_2 PF02767.16 EIM91954.1 - 0.051 13.8 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Glycos_transf_2 PF00535.26 EIM91956.1 - 1.1e-32 113.2 0.0 1.4e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EIM91956.1 - 4.5e-14 52.9 0.0 6.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EIM91956.1 - 0.0029 17.1 0.0 0.0037 16.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 EIM91956.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 F-box-like PF12937.7 EIM91957.1 - 3.7e-07 29.9 0.0 6.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM91957.1 - 7.5e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 F-box domain Sel1 PF08238.12 EIM91958.1 - 1.8e-15 57.0 10.5 1e-05 26.1 0.0 3.3 3 0 0 3 3 3 3 Sel1 repeat PBP PF01161.20 EIM91959.1 - 4.2e-14 53.0 0.8 7.7e-14 52.1 0.8 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF1180 PF06679.12 EIM91959.1 - 0.086 13.3 3.9 0.17 12.3 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) BTB PF00651.31 EIM91962.1 - 8.1e-07 29.3 0.1 1.6e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BUD22 PF09073.10 EIM91963.1 - 1e-05 25.1 12.1 1e-05 25.1 12.1 2.1 3 0 0 3 3 3 1 BUD22 CDC45 PF02724.14 EIM91963.1 - 0.059 11.7 1.0 0.083 11.2 1.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EIM91963.1 - 0.75 7.9 9.3 1 7.5 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family FTHFS PF01268.19 EIM91967.1 - 5.4e-35 120.6 1.1 7.3e-35 120.2 1.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase DnaI_N PF07319.11 EIM91968.1 - 0.021 15.5 0.4 4.1 8.2 0.0 2.5 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF1635 PF07795.11 EIM91969.1 - 0.7 9.7 3.5 0.18 11.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) BUD22 PF09073.10 EIM91969.1 - 4.4 6.6 19.8 5.5 6.2 19.8 1.1 1 0 0 1 1 1 0 BUD22 DUF4413 PF14372.6 EIM91973.1 - 0.039 14.3 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 EIM91974.1 - 3.1e-13 49.3 0.1 3.8e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UPF0147 PF03685.13 EIM91975.1 - 0.11 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) zf-BED PF02892.15 EIM91976.1 - 0.047 13.7 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger Asp_protease_2 PF13650.6 EIM91979.1 - 1.1e-05 26.0 0.0 1.3e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 EIM91979.1 - 0.00019 21.5 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon peptidase gag-asp_proteas PF13975.6 EIM91979.1 - 0.00056 20.4 0.0 0.00068 20.1 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EIM91979.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF5104 PF17117.5 EIM91980.1 - 0.18 12.2 0.0 0.63 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) Retrotrans_gag PF03732.17 EIM91980.1 - 0.33 11.2 2.3 1.1 9.5 2.3 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein DUF4623 PF15416.6 EIM91981.1 - 0.064 11.8 0.0 0.064 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) Spindle_Spc25 PF08234.12 EIM91982.1 - 1.6e-05 25.0 0.0 6.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Leu_zip PF15294.6 EIM91982.1 - 0.0025 17.4 4.6 0.0031 17.1 4.0 1.4 1 1 0 1 1 1 1 Leucine zipper Spc7 PF08317.11 EIM91982.1 - 0.0044 16.0 3.8 0.0056 15.6 3.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EIM91982.1 - 0.0049 16.9 6.0 0.005 16.9 5.2 1.5 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 EIM91982.1 - 0.0075 16.7 6.7 0.012 16.0 6.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Golgin_A5 PF09787.9 EIM91982.1 - 0.012 15.2 4.0 0.015 14.8 4.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Rootletin PF15035.6 EIM91982.1 - 0.015 15.4 7.2 0.019 15.0 7.2 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 EIM91982.1 - 0.044 13.8 3.5 0.11 12.5 3.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 EIM91982.1 - 0.047 12.4 4.5 0.057 12.1 4.5 1.1 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 EIM91982.1 - 0.067 13.7 8.1 0.15 12.6 8.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region FUSC PF04632.12 EIM91982.1 - 0.12 10.9 2.1 0.14 10.6 2.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 EIM91982.1 - 0.19 10.3 3.7 0.23 10.0 3.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 EIM91982.1 - 0.22 12.1 5.3 0.38 11.4 0.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 EIM91982.1 - 0.26 9.2 1.8 0.3 9.0 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 EIM91982.1 - 0.45 10.7 9.0 1 9.6 5.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Bcr-Abl_Oligo PF09036.10 EIM91982.1 - 0.71 9.9 3.3 19 5.3 0.5 3.0 1 1 2 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain CLZ PF16526.5 EIM91982.1 - 0.8 10.1 5.4 5.3 7.5 2.4 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 EIM91982.1 - 0.96 9.3 5.4 0.36 10.6 0.6 2.3 2 1 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 EIM91982.1 - 1.4 9.4 7.0 11 6.6 7.0 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.25 EIM91983.1 - 1.1e-60 205.2 0.0 3.3e-60 203.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM91983.1 - 2.1e-29 102.6 0.1 2.6e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIM91983.1 - 9.6e-05 21.8 0.7 0.009 15.3 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EIM91983.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIM91983.1 - 0.0031 16.9 0.3 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM91983.1 - 0.0088 16.0 0.1 0.095 12.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EIM91983.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MFS_1 PF07690.16 EIM91984.1 - 1.4e-13 50.6 32.6 1.4e-13 50.6 32.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EIM91984.1 - 1.9e-11 43.9 6.0 1.9e-11 43.9 6.0 2.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 TB2_DP1_HVA22 PF03134.19 EIM91985.1 - 3.9e-26 90.8 7.0 3.9e-26 90.8 7.0 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family TFIIS_C PF01096.18 EIM91986.1 - 1.7e-16 59.8 0.9 1.7e-16 59.8 0.9 3.0 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EIM91986.1 - 1.1e-08 34.8 6.0 1.1e-07 31.6 0.4 2.9 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 EIM91986.1 - 0.00017 21.5 9.0 0.003 17.5 0.4 2.8 2 1 1 3 3 3 1 Double zinc ribbon Mu-like_Com PF10122.9 EIM91986.1 - 0.001 18.5 1.8 0.92 9.0 0.7 2.3 2 0 0 2 2 2 2 Mu-like prophage protein Com Baculo_LEF5_C PF11792.8 EIM91986.1 - 0.0018 17.9 3.9 0.015 15.0 1.3 2.6 2 1 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain Lar_restr_allev PF14354.6 EIM91986.1 - 0.0026 18.1 6.1 0.11 12.9 0.4 2.3 2 0 0 2 2 2 2 Restriction alleviation protein Lar zinc_ribbon_13 PF09855.9 EIM91986.1 - 0.01 16.0 4.7 3.4 7.9 1.6 3.0 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-ribbon_3 PF13248.6 EIM91986.1 - 0.017 14.5 12.4 0.87 9.1 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf_UBZ PF18439.1 EIM91986.1 - 0.018 14.6 7.1 6 6.5 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 EIM91986.1 - 0.03 14.3 6.2 0.05 13.6 0.2 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.6 EIM91986.1 - 0.032 14.8 3.4 2.3 8.8 0.1 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.13 EIM91986.1 - 0.045 13.4 10.7 0.16 11.6 1.5 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Elf1 PF05129.13 EIM91986.1 - 0.084 12.9 9.0 0.15 12.1 1.4 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like IBR PF01485.21 EIM91986.1 - 0.094 13.0 8.6 0.84 9.9 0.2 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DUF2387 PF09526.10 EIM91986.1 - 0.12 12.6 6.5 0.59 10.3 0.6 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) PHD PF00628.29 EIM91986.1 - 0.2 11.6 9.8 0.77 9.7 0.6 2.9 2 1 1 3 3 3 0 PHD-finger zinc_ribbon_2 PF13240.6 EIM91986.1 - 0.22 11.3 12.1 4.8 7.0 0.5 3.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 EIM91986.1 - 0.23 11.3 4.0 3 7.7 0.1 2.9 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO HypA PF01155.19 EIM91986.1 - 0.3 11.1 8.4 0.45 10.5 0.6 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 EIM91986.1 - 0.43 10.5 8.0 1.3 9.0 0.4 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-IS66 PF13005.7 EIM91986.1 - 0.64 10.5 10.4 5.5 7.5 0.1 3.6 4 0 0 4 4 3 0 zinc-finger binding domain of transposase IS66 CpXC PF14353.6 EIM91986.1 - 0.66 10.0 8.3 7 6.7 0.2 3.0 2 1 0 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.10 EIM91986.1 - 0.72 10.0 14.8 1.8 8.8 1.9 3.3 2 1 0 3 3 3 0 Zinc ribbon domain Terminase_GpA PF05876.12 EIM91986.1 - 0.79 8.2 4.6 1.3 7.5 1.1 2.0 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Rubredoxin_2 PF18073.1 EIM91986.1 - 0.82 9.5 0.1 0.82 9.5 0.1 3.8 4 0 0 4 4 4 0 Rubredoxin metal binding domain DUF4379 PF14311.6 EIM91986.1 - 0.91 9.9 7.6 3 8.3 1.0 3.2 2 1 1 3 3 3 0 Probable Zinc-ribbon domain DUF3268 PF11672.8 EIM91986.1 - 1.3 9.3 5.4 0.66 10.3 0.5 2.5 3 1 0 3 3 3 0 zinc-finger-containing domain TF_Zn_Ribbon PF08271.12 EIM91986.1 - 1.6 8.3 16.8 0.58 9.7 0.5 3.8 2 2 2 4 4 4 0 TFIIB zinc-binding zf-NADH-PPase PF09297.11 EIM91986.1 - 2.4 7.9 13.4 20 4.9 0.4 3.3 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-RING_7 PF02591.15 EIM91986.1 - 2.8 8.2 9.9 16 5.8 0.0 3.7 3 1 1 4 4 4 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 EIM91986.1 - 3.6 7.6 11.0 34 4.5 0.2 3.9 3 1 1 4 4 4 0 zinc-ribbon domain DUF1451 PF07295.11 EIM91986.1 - 7.4 6.6 11.7 1.4 9.0 0.2 2.9 1 1 2 3 3 3 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 EIM91986.1 - 9.3 6.1 11.5 25 4.7 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain MutS_V PF00488.21 EIM91989.1 - 4.8e-58 196.3 0.1 1.1e-57 195.1 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIM91989.1 - 3.4e-29 102.4 0.5 3.4e-29 102.4 0.5 2.0 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EIM91989.1 - 1.4e-06 28.6 0.0 7.1e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EIM91989.1 - 3.9e-06 27.1 0.0 9.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV TMEM189_B_dmain PF10520.9 EIM91989.1 - 0.055 13.6 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain ArfGap PF01412.18 EIM91990.1 - 4e-42 143.0 0.3 6.4e-42 142.3 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TFIIA PF03153.13 EIM91990.1 - 0.45 10.5 18.0 0.6 10.0 18.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.10 EIM91991.1 - 1.5e-09 38.0 0.0 1.4e-08 34.8 0.0 2.4 1 1 0 1 1 1 1 GET complex subunit GET2 L51_S25_CI-B8 PF05047.16 EIM91992.1 - 3.9e-09 36.3 0.3 6.4e-09 35.6 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MRP_L53 PF10780.9 EIM91992.1 - 0.00029 21.0 0.0 0.00093 19.3 0.0 1.9 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 YL1 PF05764.13 EIM91993.1 - 8.2e-38 130.9 19.4 9.7e-38 130.7 19.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SRP-alpha_N PF04086.13 EIM91993.1 - 0.027 14.4 13.6 0.039 13.9 13.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TA_inhibitor PF17574.2 EIM91993.1 - 0.057 13.5 0.4 0.13 12.3 0.4 1.6 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) Peptidase_M1 PF01433.20 EIM91994.1 - 3e-36 125.0 0.0 4.1e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EIM91994.1 - 5.9e-29 100.4 0.0 1.2e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EIM91994.1 - 3.9e-19 69.5 0.1 6.7e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EIM91994.1 - 1.5 9.3 4.3 40 4.6 4.4 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Nup160 PF11715.8 EIM91995.1 - 3e-33 115.3 0.0 4.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EIM91995.1 - 0.0039 16.0 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like SET PF00856.28 EIM91996.1 - 1.4e-11 45.1 0.0 3.9e-11 43.6 0.0 1.9 1 1 0 1 1 1 1 SET domain adh_short PF00106.25 EIM91997.1 - 1.5e-15 57.2 0.0 5e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM91997.1 - 1.6e-09 37.7 0.0 4.2e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM91997.1 - 2.6e-08 34.0 0.1 4.6e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EIM91997.1 - 0.092 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Adaptin_N PF01602.20 EIM91998.1 - 6.6e-06 25.0 1.7 7e-05 21.6 0.0 2.9 3 0 0 3 3 3 1 Adaptin N terminal region HEAT_2 PF13646.6 EIM91998.1 - 1e-05 25.8 8.6 0.14 12.5 0.3 6.9 5 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 EIM91998.1 - 3.4e-05 24.2 6.8 0.95 10.0 0.1 6.6 6 0 0 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 EIM91998.1 - 0.0076 16.4 0.1 1.2 9.3 0.0 4.4 3 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EIM91998.1 - 0.013 15.7 11.3 68 4.1 0.0 9.0 11 0 0 11 11 11 0 HEAT repeat Arm PF00514.23 EIM91998.1 - 0.05 13.7 0.0 0.82 9.8 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3619 PF12279.8 EIM91998.1 - 0.15 12.4 4.3 1 9.7 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Syja_N PF02383.18 EIM91999.1 - 1.2e-77 261.4 0.0 1.8e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Pkinase_fungal PF17667.1 EIM92000.1 - 1.3e-48 165.8 0.1 1.5e-31 109.6 0.7 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EIM92000.1 - 1.2e-07 31.9 0.1 6.5e-05 23.0 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 EIM92000.1 - 4.8e-07 29.4 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SLT_2 PF13406.6 EIM92000.1 - 0.067 12.4 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain Oxidored-like PF09791.9 EIM92001.1 - 2e-19 68.9 0.5 3.5e-19 68.2 0.5 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DAO PF01266.24 EIM92002.1 - 1.3e-27 97.3 0.2 1.9e-26 93.5 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM92002.1 - 0.032 14.4 0.0 0.087 13.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM92002.1 - 0.038 13.2 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PDZ_5 PF17817.1 EIM92003.1 - 0.096 13.0 0.3 0.82 10.0 0.0 2.6 2 0 0 2 2 2 0 PDZ domain p450 PF00067.22 EIM92004.1 - 4.6e-63 213.6 0.0 8.1e-63 212.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EIM92005.1 - 3.5e-39 134.8 0.0 5.8e-39 134.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 EIM92006.1 - 1.8e-14 54.1 0.3 2.4e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM92006.1 - 7.4e-11 41.6 0.0 2.1e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EIM92006.1 - 2.7e-06 26.5 0.0 3.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EIM92006.1 - 8.7e-05 23.2 4.0 0.00011 22.9 4.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIM92006.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EIM92006.1 - 0.02 14.1 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 EIM92007.1 - 3.2e-38 131.7 0.0 2.6e-37 128.6 0.0 2.0 3 0 0 3 3 3 1 Cytochrome P450 zf-C2H2 PF00096.26 EIM92008.1 - 2 9.0 8.0 7.4 7.2 2.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Vps35 PF03635.17 EIM92009.1 - 1.2e-303 1009.2 0.0 1.4e-303 1009.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 EIM92009.1 - 0.052 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Endoribonuclease L-PSP VHS PF00790.19 EIM92010.1 - 8.1e-43 145.7 0.1 3.6e-42 143.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EIM92010.1 - 6.3e-16 58.3 6.1 1.1e-15 57.5 6.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EIM92010.1 - 2e-05 24.2 12.9 0.0086 15.9 3.3 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 EIM92010.1 - 0.00044 20.5 0.1 0.0017 18.6 0.1 2.1 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 EIM92010.1 - 0.0019 18.4 3.4 0.0038 17.4 3.4 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 EIM92010.1 - 0.11 12.6 6.7 3 7.9 2.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon ADK_lid PF05191.14 EIM92010.1 - 0.46 10.5 2.1 2.1 8.4 2.1 2.2 1 0 0 1 1 1 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 EIM92010.1 - 0.91 9.7 3.1 0.92 9.7 1.0 2.0 1 1 1 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 EIM92010.1 - 1.2 9.1 4.0 0.35 10.8 0.7 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RNA_pol_Rpb1_1 PF04997.12 EIM92011.1 - 1.7e-108 362.7 0.0 2.6e-108 362.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EIM92011.1 - 5.1e-108 360.5 0.0 9.1e-108 359.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EIM92011.1 - 3.5e-74 248.5 0.0 7.8e-74 247.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EIM92011.1 - 1e-67 227.7 0.0 2e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EIM92011.1 - 1.1e-50 171.6 0.1 7.4e-50 168.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EIM92011.1 - 2.7e-49 166.6 1.4 2.7e-49 166.6 1.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EIM92011.1 - 1.9e-36 124.3 0.0 4e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EIM92011.1 - 0.0022 18.3 118.5 0.025 14.9 10.5 9.7 4 1 10 14 14 14 10 RNA polymerase Rpb1 C-terminal repeat ADD_DNMT3 PF17980.1 EIM92011.1 - 0.18 11.8 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 TIP120 PF08623.10 EIM92013.1 - 4.4e-56 189.3 1.3 2.5e-54 183.6 0.1 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EIM92013.1 - 9.1e-16 56.6 12.5 0.23 11.8 0.1 13.2 14 0 0 14 14 14 1 HEAT repeat HEAT_2 PF13646.6 EIM92013.1 - 2.7e-15 56.5 16.6 0.079 13.4 0.3 9.9 8 2 5 13 13 12 6 HEAT repeats HEAT_EZ PF13513.6 EIM92013.1 - 7.1e-14 51.9 17.9 0.0029 18.1 0.3 12.0 13 1 0 13 13 13 3 HEAT-like repeat CLASP_N PF12348.8 EIM92013.1 - 2e-12 47.2 0.5 1.9e-05 24.4 0.0 4.8 5 0 0 5 5 5 3 CLASP N terminal Adaptin_N PF01602.20 EIM92013.1 - 1.5e-09 37.0 0.2 0.06 11.9 0.0 5.9 3 1 1 4 4 4 3 Adaptin N terminal region DUF3385 PF11865.8 EIM92013.1 - 3.2e-07 30.4 0.5 0.00033 20.6 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EIM92013.1 - 1.1e-06 28.1 16.4 0.0035 16.5 1.6 4.9 4 0 0 4 4 4 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EIM92013.1 - 1.2e-06 29.0 0.3 19 5.9 0.0 7.2 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 EIM92013.1 - 6.6e-06 25.9 4.9 0.03 13.9 0.0 5.2 5 0 0 5 5 5 1 Tti2 family Cnd1 PF12717.7 EIM92013.1 - 1.8e-05 24.9 3.4 3.2 7.8 0.0 6.3 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EIM92013.1 - 5.7e-05 23.3 0.8 0.3 11.2 0.0 4.9 5 0 0 5 5 5 1 Parkin co-regulated protein RTP1_C1 PF10363.9 EIM92013.1 - 8.6e-05 22.7 0.8 0.067 13.4 0.1 4.4 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 EIM92013.1 - 0.00038 20.3 0.5 1.1 9.3 0.0 4.7 4 1 0 4 4 3 1 UME (NUC010) domain RIX1 PF08167.12 EIM92013.1 - 0.0016 18.2 9.2 3.2 7.4 0.1 5.5 6 1 0 6 6 6 2 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 EIM92013.1 - 0.0036 17.6 0.0 3.9 7.9 0.0 4.8 4 1 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain V-ATPase_H_C PF11698.8 EIM92013.1 - 0.0037 17.4 1.4 1.1 9.4 0.1 4.7 5 1 0 5 5 5 1 V-ATPase subunit H Arm PF00514.23 EIM92013.1 - 0.83 9.8 6.0 1e+02 3.2 0.0 5.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF4611 PF15387.6 EIM92013.1 - 0.95 9.7 4.2 1.3 9.3 2.6 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) Pro_dh PF01619.18 EIM92014.1 - 8.2e-48 163.4 0.0 9.4e-26 91.0 0.0 2.9 2 1 0 2 2 2 2 Proline dehydrogenase BCIP PF13862.6 EIM92015.1 - 3e-66 223.1 0.0 4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Myb_Cef PF11831.8 EIM92017.1 - 1.4e-65 221.2 3.9 1.4e-65 221.2 3.9 4.1 5 1 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EIM92017.1 - 3.2e-22 78.5 6.0 9.4e-11 41.7 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIM92017.1 - 1.9e-19 69.6 6.9 1.2e-12 47.8 3.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EIM92017.1 - 2.4 8.3 6.2 2.6 8.2 0.1 3.5 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SET PF00856.28 EIM92019.1 - 2.2e-11 44.5 0.2 2.8e-10 40.8 0.2 2.5 1 1 0 1 1 1 1 SET domain Med9 PF07544.13 EIM92020.1 - 7.6e-07 29.1 1.0 9.8e-07 28.8 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Fer4_14 PF13394.6 EIM92020.1 - 0.042 14.0 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain HBS1_N PF08938.10 EIM92020.1 - 0.056 13.7 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 HBS1 N-terminus GPI-anchored PF10342.9 EIM92021.1 - 2.1e-06 28.4 0.4 5.3e-06 27.1 0.4 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA PF00004.29 EIM92022.1 - 5.9e-42 143.2 0.0 9.9e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EIM92022.1 - 5.2e-28 96.8 0.6 1.7e-27 95.2 0.6 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EIM92022.1 - 3.9e-23 81.3 9.3 9.2e-23 80.1 9.3 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EIM92022.1 - 1.8e-06 27.7 0.1 9.8e-06 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EIM92022.1 - 3.1e-06 27.7 0.3 4.2e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM92022.1 - 5.2e-06 26.8 1.0 0.0016 18.7 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EIM92022.1 - 5.3e-06 26.3 0.0 3.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EIM92022.1 - 1e-05 25.6 0.0 5e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIM92022.1 - 4.1e-05 23.4 0.0 0.0001 22.1 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EIM92022.1 - 0.00016 21.7 0.1 0.00047 20.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 EIM92022.1 - 0.00031 20.9 0.0 0.0057 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EIM92022.1 - 0.00065 19.9 0.3 0.0041 17.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EIM92022.1 - 0.00078 20.0 0.2 0.0048 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EIM92022.1 - 0.00091 18.5 0.0 0.0019 17.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 EIM92022.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 EIM92022.1 - 0.0016 18.2 0.1 0.0078 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIM92022.1 - 0.0038 17.6 0.0 0.0098 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase PF06745.13 EIM92022.1 - 0.012 14.9 0.1 4.7 6.5 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 EIM92022.1 - 0.015 14.9 0.2 0.83 9.2 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 EIM92022.1 - 0.019 15.4 0.0 0.057 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain KAsynt_C_assoc PF16197.5 EIM92022.1 - 0.019 15.4 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension AAA_7 PF12775.7 EIM92022.1 - 0.027 14.0 0.2 0.24 10.9 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EIM92022.1 - 0.028 13.8 0.0 5.9 6.2 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein Nop14 PF04147.12 EIM92022.1 - 0.033 12.4 2.7 0.045 12.0 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family Mg_chelatase PF01078.21 EIM92022.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EIM92022.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EIM92022.1 - 0.063 13.2 0.0 0.22 11.5 0.0 2.0 1 1 0 1 1 1 0 NACHT domain TPR_1 PF00515.28 EIM92022.1 - 0.065 13.1 2.4 9 6.3 2.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PhoH PF02562.16 EIM92022.1 - 0.075 12.5 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 EIM92022.1 - 0.083 12.8 1.6 1.4 8.7 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 EIM92022.1 - 0.14 12.0 0.2 19 5.1 0.0 2.7 2 1 1 3 3 3 0 Rad17 P-loop domain Sigma54_activat PF00158.26 EIM92022.1 - 0.16 11.6 0.0 0.65 9.7 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EIM92022.1 - 0.17 12.0 0.0 0.54 10.4 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain FlhD PF05247.13 EIM92022.1 - 0.19 12.0 0.2 0.43 10.9 0.2 1.6 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) TPR_2 PF07719.17 EIM92022.1 - 6 7.2 9.5 13 6.2 1.9 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM92022.1 - 8.8 6.8 6.8 16 6.1 0.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Big_6 PF17936.1 EIM92023.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig domain Macoilin PF09726.9 EIM92024.1 - 0.0024 16.5 5.1 0.0031 16.2 5.1 1.2 1 0 0 1 1 1 1 Macoilin family DUF3584 PF12128.8 EIM92024.1 - 0.81 7.1 18.7 1.1 6.7 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 EIM92024.1 - 0.87 9.8 25.5 0.066 13.4 15.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SKA2 PF16740.5 EIM92024.1 - 2.3 8.0 7.1 1.9 8.3 0.1 2.5 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Fez1 PF06818.15 EIM92024.1 - 3.1 8.2 20.6 8.6 6.8 20.7 1.6 1 1 0 1 1 1 0 Fez1 DUF4200 PF13863.6 EIM92024.1 - 4.5 7.7 18.4 3.6 8.0 13.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF5082 PF16888.5 EIM92024.1 - 6.3 7.1 13.7 12 6.2 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) ALIX_LYPXL_bnd PF13949.6 EIM92024.1 - 7.7 5.7 18.1 2 7.6 14.5 1.6 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Pkinase PF00069.25 EIM92025.1 - 5.1e-56 189.9 0.0 6.6e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92025.1 - 1.5e-24 86.7 0.0 2.1e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM92025.1 - 3.1e-05 23.4 0.6 0.00015 21.2 0.1 2.3 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EIM92025.1 - 0.024 14.3 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EIM92025.1 - 0.07 13.0 0.0 5.2 6.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EIM92025.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cas_Cmr3 PF09700.10 EIM92026.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Ribosomal_L19e PF01280.20 EIM92027.1 - 6.6e-60 201.4 11.1 6.6e-60 201.4 11.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e MOZ_SAS PF01853.18 EIM92029.1 - 3.9e-63 212.3 0.6 7.9e-63 211.3 0.3 1.6 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 EIM92029.1 - 1.3e-18 66.4 3.0 1.3e-18 66.4 3.0 2.4 2 1 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EIM92029.1 - 0.00071 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM92029.1 - 0.0063 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase PF00069.25 EIM92030.1 - 5.6e-24 84.9 0.0 8.8e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92030.1 - 1.9e-11 43.7 0.0 2.5e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM92030.1 - 0.0085 15.4 0.0 0.04 13.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM92030.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPT PF03169.15 EIM92032.1 - 1.6e-177 591.9 46.8 1.8e-177 591.7 46.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Aldo_ket_red PF00248.21 EIM92034.1 - 1.6e-48 165.4 0.0 1.9e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pectinesterase PF01095.19 EIM92036.1 - 8.3e-35 119.9 0.2 1.1e-34 119.5 0.2 1.1 1 0 0 1 1 1 1 Pectinesterase AAA_18 PF13238.6 EIM92037.1 - 0.0051 17.4 0.0 0.094 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 EIM92037.1 - 0.045 13.5 0.1 0.47 10.2 0.1 2.1 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EIM92037.1 - 0.059 13.5 0.1 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EIM92037.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Bromodomain PF00439.25 EIM92039.1 - 1.6e-27 95.4 0.3 1.2e-17 63.7 0.4 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EIM92039.1 - 2.2e-07 30.8 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-C2H2 PF00096.26 EIM92040.1 - 0.00016 21.9 0.3 0.00031 21.0 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM92040.1 - 0.00054 20.3 2.3 0.002 18.5 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM92040.1 - 0.003 18.2 0.9 0.0063 17.3 0.9 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIM92040.1 - 0.0077 16.0 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EIM92040.1 - 0.0091 15.9 1.5 0.016 15.1 1.5 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type FYVE PF01363.21 EIM92040.1 - 0.05 13.8 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger adh_short PF00106.25 EIM92041.1 - 4.7e-20 71.9 0.0 5.1e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM92041.1 - 5e-12 45.9 0.0 4.4e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM92041.1 - 2.6e-09 37.2 0.0 8.5e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 EIM92041.1 - 0.076 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EIM92041.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4763 PF15960.5 EIM92042.1 - 0.041 13.2 0.2 0.041 13.2 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) WD40_alt PF14077.6 EIM92042.1 - 0.47 10.4 2.4 1.8 8.5 0.1 2.7 1 1 1 2 2 2 0 Alternative WD40 repeat motif OPT PF03169.15 EIM92043.1 - 5.9e-170 566.9 56.7 6.7e-170 566.7 56.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_transf_25 PF01755.17 EIM92044.1 - 8.7e-08 32.3 0.0 5.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-ANAPC11 PF12861.7 EIM92045.1 - 1.3e-40 137.4 10.8 1.5e-40 137.2 10.8 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EIM92045.1 - 9.7e-22 77.0 11.4 1.5e-21 76.4 11.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EIM92045.1 - 7e-05 23.1 18.3 0.0008 19.7 17.4 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIM92045.1 - 0.0048 16.7 4.8 0.0048 16.7 4.8 2.5 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM92045.1 - 0.043 13.9 11.2 0.098 12.7 11.2 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.8 EIM92045.1 - 0.071 12.9 3.3 0.11 12.3 3.3 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EIM92045.1 - 0.1 12.2 16.6 0.11 12.1 13.6 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EIM92045.1 - 0.17 11.8 15.6 1 9.3 15.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM92045.1 - 0.2 11.7 14.5 4.7 7.3 15.3 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EIM92045.1 - 2.5 7.9 13.9 14 5.5 13.9 2.2 1 1 0 1 1 1 0 RING-like zinc finger RINGv PF12906.7 EIM92045.1 - 5.6 7.2 14.3 4 7.6 10.9 2.3 1 1 1 2 2 2 0 RING-variant domain SET PF00856.28 EIM92046.1 - 2.2e-09 37.9 0.0 3.4e-08 34.0 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EIM92046.1 - 3.9e-09 35.9 5.4 0.00049 20.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIM92046.1 - 4.9e-09 35.6 1.6 0.00039 20.1 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM92046.1 - 1.3e-06 28.0 0.0 4.6e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 EIM92046.1 - 2.9e-05 24.5 0.3 0.0023 18.4 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EIM92046.1 - 7.7e-05 22.8 2.0 0.0023 18.0 1.8 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIM92046.1 - 0.00051 20.6 9.7 0.0024 18.5 2.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM92046.1 - 0.0054 16.8 0.4 0.014 15.5 0.1 1.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EIM92046.1 - 0.022 15.1 0.7 0.82 10.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 EIM92046.1 - 0.074 12.7 0.4 0.26 11.0 0.1 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EIM92046.1 - 0.14 12.2 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM92046.1 - 0.19 12.1 0.5 0.68 10.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 EIM92046.1 - 1.2 9.4 3.8 6.2 7.1 0.7 2.8 1 1 1 2 2 2 0 HemY protein N-terminus TPR_2 PF07719.17 EIM92047.1 - 8e-08 31.8 0.7 9e-05 22.3 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM92047.1 - 1.4e-05 24.7 0.4 0.00026 20.7 0.3 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIM92047.1 - 0.00027 20.5 0.1 0.003 17.2 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 EIM92047.1 - 0.00036 20.6 0.1 0.1 12.8 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM92047.1 - 0.0018 18.9 0.1 0.22 12.2 0.1 2.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIM92047.1 - 0.028 14.7 1.5 1.4 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIM92047.1 - 0.13 12.5 0.1 0.39 11.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM92047.1 - 0.2 12.4 0.8 25 5.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIM92047.1 - 0.47 11.4 2.7 4 8.5 0.1 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat SET PF00856.28 EIM92048.1 - 7.8e-09 36.1 0.0 3.7e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EIM92048.1 - 0.00045 20.1 0.9 0.044 13.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EIM92048.1 - 0.00052 20.1 1.2 0.0011 19.1 1.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIM92048.1 - 0.068 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIM92048.1 - 0.28 11.3 0.6 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat PCI PF01399.27 EIM92049.1 - 1.3e-06 28.9 0.7 2.9e-06 27.7 0.7 1.6 1 0 0 1 1 1 1 PCI domain Rgp1 PF08737.10 EIM92050.1 - 2.3e-47 162.1 0.0 4.1e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 EIM92050.1 - 0.00092 19.7 0.0 3.9 7.9 0.0 3.9 4 0 0 4 4 4 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EIM92050.1 - 0.026 14.6 0.3 0.77 9.8 0.1 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain PSP1 PF04468.12 EIM92052.1 - 1.4e-31 108.6 2.5 1.4e-31 108.6 2.5 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region tRNA-synt_1c PF00749.21 EIM92053.1 - 1.6e-79 267.1 0.0 2.4e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Chorion_2 PF03964.15 EIM92053.1 - 0.017 15.9 0.9 0.046 14.6 0.9 1.7 1 0 0 1 1 1 0 Chorion family 2 MFMR_assoc PF16596.5 EIM92053.1 - 0.48 10.9 7.1 0.86 10.1 7.1 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR SSP160 PF06933.11 EIM92053.1 - 3.1 5.9 5.1 4.3 5.4 5.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AF-4 PF05110.13 EIM92053.1 - 6.5 4.7 14.2 9.3 4.2 14.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-UBR PF02207.20 EIM92055.1 - 3.1e-15 56.1 20.1 3.1e-15 56.1 20.1 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EIM92055.1 - 2.2e-09 37.0 0.1 5.8e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS TRAPP PF04051.16 EIM92056.1 - 6.9e-34 116.7 0.0 9.9e-34 116.2 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component CTF_NFI PF00859.18 EIM92056.1 - 0.09 12.7 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region NeA_P2 PF12312.8 EIM92056.1 - 0.098 12.1 0.4 0.3 10.5 0.2 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein CAP_N PF01213.19 EIM92056.1 - 0.15 11.6 0.7 0.21 11.0 0.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short_C2 PF13561.6 EIM92058.1 - 4e-52 177.1 5.6 3.7e-42 144.5 3.8 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM92058.1 - 1.7e-44 151.6 1.9 2.1e-44 151.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM92058.1 - 9.3e-14 51.7 0.2 1.6e-13 50.9 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EIM92058.1 - 0.079 12.8 0.6 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain A_deaminase PF00962.22 EIM92059.1 - 4.1e-20 72.4 0.0 2.4e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase PI-PLC-X PF00388.19 EIM92059.1 - 0.063 12.9 0.0 0.64 9.6 0.0 2.3 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Tyosinase_C PF18132.1 EIM92059.1 - 0.2 12.3 0.0 0.45 11.2 0.0 1.6 1 0 0 1 1 1 0 Tyosinase C-terminal domain DUF3752 PF12572.8 EIM92060.1 - 4.4e-40 137.7 12.4 4.4e-40 137.7 12.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Ly-6_related PF06579.12 EIM92061.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein NmrA PF05368.13 EIM92062.1 - 9.8e-21 74.4 0.0 1.3e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIM92062.1 - 3.2e-13 50.0 0.0 5.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM92062.1 - 9.3e-07 28.5 0.0 4e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIM92062.1 - 6.9e-06 25.3 0.0 9.9e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EIM92062.1 - 0.0017 18.3 0.0 0.0047 16.8 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 EIM92062.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIM92062.1 - 0.075 12.1 0.0 0.15 11.2 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EIM92062.1 - 0.088 12.0 0.2 0.21 10.7 0.1 1.7 1 1 1 2 2 2 0 Male sterility protein G-alpha PF00503.20 EIM92063.1 - 3.6e-100 335.6 0.0 4.8e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIM92063.1 - 2.7e-11 43.2 2.9 1.3e-07 31.2 0.6 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM92063.1 - 0.0059 16.7 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIM92063.1 - 0.028 14.0 0.1 7.6 6.0 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EIM92063.1 - 0.13 11.6 0.3 17 4.8 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EIM92063.1 - 0.16 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EIM92063.1 - 0.21 10.9 5.9 2 7.7 0.3 2.7 3 1 0 3 3 3 0 Gtr1/RagA G protein conserved region Roc PF08477.13 EIM92063.1 - 0.34 11.1 1.5 2.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Alpha_kinase PF02816.18 EIM92067.1 - 5.1e-16 59.3 0.0 9.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family Vps36-NZF-N PF16988.5 EIM92067.1 - 0.0027 17.1 0.8 0.0073 15.7 0.8 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain ANAPC4_WD40 PF12894.7 EIM92075.1 - 1.4e-08 34.9 0.0 0.0075 16.5 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM92075.1 - 4.5e-06 27.3 2.8 7.5 7.6 0.0 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF2415 PF10313.9 EIM92075.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SPO22 PF08631.10 EIM92076.1 - 6.5e-51 173.4 4.1 3.4e-46 158.0 0.1 3.4 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like SNAP PF14938.6 EIM92076.1 - 0.014 14.8 0.9 0.029 13.8 0.1 1.9 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 EIM92076.1 - 0.016 15.4 1.6 0.078 13.2 1.6 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EIM92076.1 - 6.7 7.3 11.1 0.31 11.6 0.2 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIM92076.1 - 7 7.0 8.5 9.3 6.6 0.5 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.20 EIM92077.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 MAP65_ASE1 PF03999.12 EIM92077.1 - 0.17 10.5 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Cyclin PF08613.11 EIM92078.1 - 1.2e-15 58.3 0.0 2.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EIM92078.1 - 8.8e-09 35.2 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs7 PF12271.8 EIM92080.1 - 4.7e-117 390.4 22.4 5.4e-117 390.3 22.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone WD40 PF00400.32 EIM92081.1 - 2.5e-24 85.1 12.3 3.9e-05 24.3 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EIM92081.1 - 8.4e-09 34.6 0.1 0.00057 18.7 0.0 3.8 3 1 0 4 4 4 2 Nucleoporin Nup120/160 DUF5046 PF16465.5 EIM92081.1 - 0.003 17.1 0.4 0.88 9.0 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF5046) CENP-F_leu_zip PF10473.9 EIM92081.1 - 0.073 13.1 12.6 0.11 12.5 12.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 EIM92081.1 - 0.31 9.2 6.6 0.44 8.7 6.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BC10 PF06726.12 EIM92082.1 - 5.3e-10 39.4 12.5 1.1e-09 38.4 12.5 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF3678 PF12435.8 EIM92082.1 - 0.019 14.3 2.1 0.04 13.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) CS PF04969.16 EIM92083.1 - 0.0048 17.9 0.0 0.0092 17.0 0.0 1.5 2 0 0 2 2 2 1 CS domain HAD_2 PF13419.6 EIM92084.1 - 1.8e-20 73.7 0.0 2.4e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIM92084.1 - 8.8e-13 49.0 0.0 1.8e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIM92084.1 - 4.1e-10 39.6 0.0 2.6e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EIM92084.1 - 0.0025 18.2 0.1 0.0076 16.7 0.1 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase GHMP_kinases_N PF00288.26 EIM92086.1 - 1.2e-08 35.1 0.4 2.6e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EIM92086.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.7 1 1 0 1 1 1 0 GHMP kinases C terminal AAA_6 PF12774.7 EIM92087.1 - 2.9e-126 420.9 0.0 2.9e-125 417.6 0.0 2.8 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EIM92087.1 - 1.5e-115 386.5 7.4 1.5e-115 386.5 7.4 3.2 2 1 1 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EIM92087.1 - 2.5e-74 249.1 0.4 2.5e-74 249.1 0.4 4.4 4 1 1 5 5 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 EIM92087.1 - 1.9e-67 227.3 0.0 1.2e-66 224.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EIM92087.1 - 3.3e-49 167.8 0.0 3.3e-49 167.8 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 EIM92087.1 - 9.7e-45 153.1 5.1 1.8e-44 152.2 5.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EIM92087.1 - 4.6e-43 146.8 0.0 1.5e-36 125.6 0.0 4.8 5 0 0 5 5 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EIM92087.1 - 1.5e-35 122.4 0.0 2.9e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EIM92087.1 - 2.7e-31 108.1 0.0 4e-30 104.4 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EIM92087.1 - 1e-26 93.6 0.0 3.6e-11 43.2 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EIM92087.1 - 9.5e-17 61.3 0.2 1.1e-15 57.8 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EIM92087.1 - 2.6e-13 50.5 0.1 0.00029 21.3 0.0 4.9 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM92087.1 - 1.7e-12 47.8 0.0 0.0062 16.8 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 EIM92087.1 - 3e-10 40.4 5.1 0.12 12.5 0.0 6.1 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 EIM92087.1 - 8.9e-09 35.9 0.0 0.67 10.3 0.0 6.2 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 EIM92087.1 - 2.7e-07 31.2 1.9 0.13 12.8 0.0 5.4 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 EIM92087.1 - 6e-06 25.5 0.0 0.009 15.1 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EIM92087.1 - 1.5e-05 24.5 0.7 0.65 9.3 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 EIM92087.1 - 1.5e-05 24.5 0.0 0.35 10.2 0.0 3.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_14 PF13173.6 EIM92087.1 - 2.9e-05 24.1 0.0 1.7 8.7 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_lid_1 PF17857.1 EIM92087.1 - 0.00019 21.6 3.4 0.00024 21.2 0.0 2.9 3 0 0 3 3 2 1 AAA+ lid domain AAA_19 PF13245.6 EIM92087.1 - 0.0002 21.7 2.9 0.31 11.4 0.0 4.9 5 0 0 5 5 4 1 AAA domain TrwB_AAD_bind PF10412.9 EIM92087.1 - 0.00033 19.7 0.1 0.65 8.8 0.0 3.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 EIM92087.1 - 0.00056 19.6 0.2 0.85 9.4 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EIM92087.1 - 0.0007 19.4 0.2 26 4.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 EIM92087.1 - 0.0035 17.1 0.6 0.77 9.5 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 EIM92087.1 - 0.014 15.1 1.6 22 4.7 0.0 4.4 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 EIM92087.1 - 0.017 15.1 0.0 25 4.7 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_25 PF13481.6 EIM92087.1 - 0.018 14.6 0.0 0.56 9.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EIM92087.1 - 0.02 15.4 3.7 14 6.2 0.0 4.5 4 0 0 4 4 3 0 ABC transporter RNA_helicase PF00910.22 EIM92087.1 - 0.02 15.3 0.1 47 4.4 0.0 4.4 4 0 0 4 4 4 0 RNA helicase TsaE PF02367.17 EIM92087.1 - 0.023 14.7 0.4 16 5.5 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 EIM92087.1 - 0.067 13.0 0.1 6.6 6.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EIM92087.1 - 0.083 12.6 0.4 12 5.6 0.1 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 EIM92087.1 - 0.11 11.9 0.4 30 3.9 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A32 protein NACHT PF05729.12 EIM92087.1 - 0.26 11.2 4.3 39 4.1 0.1 4.9 6 0 0 6 6 3 0 NACHT domain DUF4988 PF16378.5 EIM92087.1 - 0.89 9.2 4.0 0.47 10.1 0.9 2.2 2 0 0 2 2 1 0 Domain of unknown function AAA_11 PF13086.6 EIM92087.1 - 1.2 8.9 11.5 1.4 8.7 0.0 3.7 4 0 0 4 4 3 0 AAA domain Spc7 PF08317.11 EIM92087.1 - 2.3 7.0 31.1 0.021 13.7 11.0 3.8 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3867 PF12983.7 EIM92087.1 - 3.7 7.6 11.5 1.8 8.6 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3867) LSM PF01423.22 EIM92088.1 - 2.9e-14 52.5 0.4 3.8e-14 52.1 0.4 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EIM92088.1 - 0.0052 16.4 0.2 0.0089 15.7 0.2 1.4 1 0 0 1 1 1 1 Hfq protein Pex2_Pex12 PF04757.14 EIM92089.1 - 5.1e-20 72.0 4.6 8.4e-20 71.3 4.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EIM92089.1 - 3.1e-10 39.8 3.0 4.4e-10 39.3 3.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIM92089.1 - 1.9e-08 34.0 3.8 2.9e-08 33.4 3.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EIM92089.1 - 2.5e-08 34.1 7.6 3.9e-08 33.5 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIM92089.1 - 9.9e-08 31.7 5.0 1.5e-07 31.1 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM92089.1 - 1.3e-07 31.3 5.5 2.1e-07 30.7 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM92089.1 - 3.9e-06 26.8 1.9 1.2e-05 25.2 1.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIM92089.1 - 4.3e-06 26.6 6.0 6.8e-06 25.9 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EIM92089.1 - 2.3e-05 24.6 4.6 4.2e-05 23.7 4.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EIM92089.1 - 0.0041 17.2 7.1 0.0083 16.3 7.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EIM92089.1 - 0.0063 16.5 0.6 0.011 15.7 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EIM92089.1 - 0.02 15.0 4.8 0.032 14.4 3.9 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 TerY_C PF15616.6 EIM92089.1 - 0.032 14.3 1.8 0.056 13.6 1.8 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 EIM92089.1 - 0.48 10.3 6.0 0.83 9.5 6.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain 2-Hacid_dh_C PF02826.19 EIM92090.1 - 4.2e-52 176.1 0.0 8.6e-52 175.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIM92090.1 - 1.2e-33 115.6 0.0 1.6e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIM92090.1 - 0.00022 21.4 0.1 0.0013 18.9 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EIM92090.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EIM92090.1 - 0.051 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 ACT domain His_biosynth PF00977.21 EIM92091.1 - 3.5e-40 137.9 0.2 5.3e-39 134.0 0.2 2.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EIM92091.1 - 2e-20 73.4 0.0 3.2e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EIM92091.1 - 6.7e-07 29.3 0.0 0.00027 20.8 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EIM92091.1 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EIM92091.1 - 0.016 14.9 0.2 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 EphA2_TM PF14575.6 EIM92091.1 - 0.035 15.0 0.0 0.074 13.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pal1 PF08316.11 EIM92092.1 - 3.8e-14 53.6 0.2 3.8e-14 53.6 0.2 2.3 3 0 0 3 3 3 1 Pal1 cell morphology protein FA_desaturase PF00487.24 EIM92093.1 - 9.9e-26 91.1 28.0 1.6e-25 90.4 28.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIM92093.1 - 5.6e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L13e PF01294.18 EIM92094.1 - 6.6e-76 254.2 5.6 9.7e-76 253.6 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e SKG6 PF08693.10 EIM92096.1 - 0.002 17.5 1.4 0.0053 16.1 1.4 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SprB PF13573.6 EIM92096.1 - 0.0039 16.9 3.1 0.047 13.5 0.1 3.3 3 0 0 3 3 3 1 SprB repeat Phage_holin_2_4 PF16082.5 EIM92096.1 - 0.03 14.1 1.3 0.039 13.7 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like CBM_4_9 PF02018.17 EIM92096.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain Gram_pos_anchor PF00746.21 EIM92096.1 - 0.55 10.2 0.0 0.55 10.2 0.0 2.9 2 1 1 3 3 3 0 LPXTG cell wall anchor motif Romo1 PF10247.9 EIM92097.1 - 1.1e-25 89.8 9.2 1.5e-25 89.3 9.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 UPF0014 PF03649.13 EIM92098.1 - 4.2e-71 239.1 16.2 5.4e-71 238.8 16.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) DUF5592 PF17332.2 EIM92098.1 - 2.3 8.8 5.4 0.92 10.1 1.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5592) BPD_transp_1 PF00528.22 EIM92098.1 - 7.1 6.3 15.6 45 3.7 15.5 2.3 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Lipase_GDSL PF00657.22 EIM92099.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Aminotran_1_2 PF00155.21 EIM92100.1 - 5.8e-91 305.4 0.0 6.6e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Gp-FAR-1 PF05823.12 EIM92101.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) RIO1 PF01163.22 EIM92103.1 - 0.021 14.4 0.2 0.061 12.9 0.2 1.8 1 0 0 1 1 1 0 RIO1 family DUF269 PF03270.13 EIM92103.1 - 0.043 13.9 0.0 0.57 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF269 Elong_Iki1 PF10483.9 EIM92104.1 - 1.1e-12 48.0 2.7 5.2e-09 36.0 0.0 2.6 2 1 0 2 2 2 2 Elongator subunit Iki1 Acetyltransf_8 PF13523.6 EIM92105.1 - 0.071 12.8 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DLH PF01738.18 EIM92106.1 - 4.2e-25 88.6 0.0 5.6e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 EIM92106.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 EIM92106.1 - 0.23 11.0 0.0 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GTP_EFTU PF00009.27 EIM92107.1 - 5.9e-53 179.3 0.0 9.3e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIM92107.1 - 8.7e-43 145.2 0.0 1.9e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EIM92107.1 - 1.7e-14 54.0 1.8 2.9e-14 53.2 0.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM92107.1 - 0.0028 17.7 0.2 0.067 13.3 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NIF3 PF01784.18 EIM92107.1 - 0.047 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Semialdhyde_dhC PF02774.18 EIM92107.1 - 0.063 13.3 0.2 0.26 11.3 0.0 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU_D4 PF14578.6 EIM92107.1 - 2.6 8.0 5.7 0.26 11.2 0.6 2.0 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Pkinase PF00069.25 EIM92108.1 - 1.7e-39 135.8 0.0 3.2e-37 128.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92108.1 - 8.6e-17 61.3 0.0 8.2e-15 54.8 0.0 3.0 2 2 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM92108.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIM92108.1 - 0.00036 20.0 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM92108.1 - 0.0063 16.5 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L32e PF01655.18 EIM92109.1 - 7.8e-51 171.0 0.5 9e-51 170.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Copper-fist PF00649.18 EIM92111.1 - 9.9e-22 76.2 0.7 9.9e-22 76.2 0.7 2.5 2 0 0 2 2 2 1 Copper fist DNA binding domain F-box PF00646.33 EIM92112.1 - 2.8e-09 36.6 0.5 1.2e-08 34.6 0.5 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIM92112.1 - 7.4e-08 32.2 0.4 7.4e-08 32.2 0.4 3.0 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 EIM92112.1 - 0.015 15.2 1.4 0.052 13.4 0.0 2.5 2 1 1 3 3 3 0 F-box Gag_spuma PF03276.14 EIM92112.1 - 0.4 9.1 2.5 0.56 8.6 2.5 1.2 1 0 0 1 1 1 0 Spumavirus gag protein UQ_con PF00179.26 EIM92113.1 - 6.4e-26 90.7 0.0 7.9e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EIM92113.1 - 0.028 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EIM92113.1 - 0.12 12.7 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Porphobil_deam PF01379.20 EIM92114.1 - 2.3e-70 236.3 0.0 3.7e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EIM92114.1 - 3.7e-17 62.4 0.4 8.5e-17 61.3 0.4 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PASTA PF03793.19 EIM92114.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 PASTA domain Nfu_N PF08712.11 EIM92115.1 - 1.1e-29 102.3 0.0 3e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EIM92115.1 - 4e-27 94.1 0.1 7.2e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Glyco_trans_1_4 PF13692.6 EIM92116.1 - 3.9e-07 30.6 0.0 6.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EIM92116.1 - 6.2e-06 26.7 0.6 1.2e-05 25.8 0.3 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 EIM92116.1 - 1.4e-05 24.7 0.0 4.5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EIM92116.1 - 5.6e-05 23.5 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EIM92116.1 - 0.015 15.3 0.4 0.029 14.4 0.4 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_hydro_18 PF00704.28 EIM92118.1 - 2.2e-63 214.9 0.7 2.6e-63 214.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 EIM92118.1 - 0.0055 16.0 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glyco_hydro_85 PF03644.13 EIM92118.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Peptidase_M24 PF00557.24 EIM92119.1 - 2.6e-44 151.4 0.1 3.1e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 GTP_EFTU PF00009.27 EIM92120.1 - 1.8e-68 229.9 0.2 2.6e-68 229.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EIM92120.1 - 6.6e-33 113.1 0.0 1.5e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EIM92120.1 - 2.9e-21 75.3 0.0 6.5e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EIM92120.1 - 2.5e-13 49.9 0.0 6.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EIM92120.1 - 3.9e-13 49.6 0.0 1.1e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM92120.1 - 1.4e-06 28.4 0.2 2.8e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EIM92120.1 - 0.066 13.0 0.2 0.31 10.8 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EIM92120.1 - 0.15 12.0 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_membrane PF00664.23 EIM92121.1 - 1.2e-47 162.8 25.9 5e-28 98.5 5.5 3.7 4 0 0 4 4 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EIM92121.1 - 3e-40 137.9 0.0 6.9e-22 78.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM92121.1 - 2.1e-12 47.0 0.0 0.00018 21.0 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIM92121.1 - 2.8e-06 28.0 0.0 0.00028 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIM92121.1 - 3.7e-06 26.7 0.0 0.038 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIM92121.1 - 1.9e-05 25.1 0.1 0.094 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EIM92121.1 - 3.2e-05 23.6 0.5 0.072 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EIM92121.1 - 3.7e-05 23.7 3.9 0.012 15.5 0.2 4.0 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EIM92121.1 - 0.00028 21.0 1.0 0.051 13.7 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 EIM92121.1 - 0.00053 19.1 0.0 0.051 12.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 EIM92121.1 - 0.00063 19.3 0.1 0.63 9.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EIM92121.1 - 0.0014 18.7 0.2 0.76 9.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 EIM92121.1 - 0.0028 16.5 0.1 0.03 13.1 0.0 2.4 3 0 0 3 3 3 1 Adenovirus IVa2 protein AAA_22 PF13401.6 EIM92121.1 - 0.0031 17.8 0.1 0.99 9.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EIM92121.1 - 0.0045 16.4 0.3 0.65 9.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EIM92121.1 - 0.0054 16.7 0.1 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 EIM92121.1 - 0.016 15.2 0.0 5.3 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIM92121.1 - 0.023 14.4 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EIM92121.1 - 0.025 14.8 0.1 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EIM92121.1 - 0.026 14.3 0.1 4.8 6.9 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase ABC_ATPase PF09818.9 EIM92121.1 - 0.038 12.8 0.5 2.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Pox_A32 PF04665.12 EIM92121.1 - 0.057 12.9 1.6 5.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA PF00004.29 EIM92121.1 - 0.067 13.6 0.3 1.5 9.2 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EIM92121.1 - 0.068 13.1 0.1 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EIM92121.1 - 0.071 12.7 1.3 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EIM92121.1 - 0.072 12.8 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 EIM92121.1 - 0.086 12.6 1.1 0.38 10.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EIM92121.1 - 0.1 12.8 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SNF2_N PF00176.23 EIM92122.1 - 2.1e-69 233.9 0.0 2.6e-68 230.3 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM92122.1 - 9.5e-14 51.7 0.0 2.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EIM92122.1 - 0.00052 19.9 3.0 0.00052 19.9 3.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIM92122.1 - 0.02 14.7 3.5 0.063 13.1 3.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 YokU PF14122.6 EIM92122.1 - 0.11 12.5 0.1 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin zf-RING_2 PF13639.6 EIM92122.1 - 0.34 11.3 4.8 1.3 9.4 4.8 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EIM92122.1 - 0.44 10.5 10.5 0.017 15.0 4.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM92122.1 - 2.6 8.0 9.5 26 4.8 9.6 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_N PF08240.12 EIM92123.1 - 1.3e-22 79.8 0.9 2.2e-22 79.0 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM92123.1 - 1e-15 57.8 0.0 2.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM92123.1 - 0.00017 21.1 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 EIM92123.1 - 0.00026 20.4 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EIM92123.1 - 0.00096 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EIM92123.1 - 0.044 13.4 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 EIM92123.1 - 0.067 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 EIM92123.1 - 0.11 13.5 0.0 0.28 12.3 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase UNC-93 PF05978.16 EIM92124.1 - 2.5e-11 43.5 4.1 2.5e-11 43.5 4.1 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EIM92124.1 - 1.3e-09 37.4 30.5 2.3e-09 36.6 21.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM92124.1 - 5.2e-06 25.6 18.4 0.0032 16.4 11.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter CUE PF02845.16 EIM92125.1 - 0.00017 21.2 0.0 0.00048 19.8 0.0 1.8 1 0 0 1 1 1 1 CUE domain API5 PF05918.11 EIM92125.1 - 1.3 7.8 4.5 2.3 6.9 4.5 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SKN1 PF03935.15 EIM92126.1 - 1.2e-190 634.3 4.4 1.5e-190 633.9 4.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 EIM92127.1 - 2.4e-194 646.4 2.6 2.9e-194 646.1 2.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BTB PF00651.31 EIM92128.1 - 3.7e-08 33.6 0.0 8.8e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain UQ_con PF00179.26 EIM92129.1 - 7.5e-21 74.2 0.0 1.2e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aldose_epim PF01263.20 EIM92130.1 - 3.2e-60 204.0 0.9 3.7e-60 203.8 0.9 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RicinB_lectin_2 PF14200.6 EIM92130.1 - 0.038 14.7 4.0 4.1 8.2 0.1 3.4 3 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like MFS_1 PF07690.16 EIM92131.1 - 7.4e-34 117.2 50.1 6.1e-33 114.2 40.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM92131.1 - 4.3e-11 42.3 25.6 1.5e-09 37.3 25.6 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Myc_target_1 PF15179.6 EIM92131.1 - 0.21 11.4 0.6 0.63 9.9 0.0 1.9 2 0 0 2 2 2 0 Myc target protein 1 F-box PF00646.33 EIM92132.1 - 1.6e-07 31.0 1.6 2.9e-07 30.2 0.3 2.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EIM92132.1 - 1.8e-07 30.9 0.2 5.1e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like NAT PF04768.13 EIM92133.1 - 2.3e-33 115.2 0.1 5e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Mito_carr PF00153.27 EIM92135.1 - 2.7e-65 216.4 5.1 3.9e-21 74.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rav1p_C PF12234.8 EIM92137.1 - 1.8e-199 664.3 0.0 2.4e-199 663.9 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Fasciclin PF02469.22 EIM92138.1 - 2.4e-69 231.5 0.0 9.5e-17 61.4 0.1 5.7 5 1 0 5 5 5 5 Fasciclin domain F-box-like PF12937.7 EIM92140.1 - 7.6e-08 32.1 4.1 7.6e-08 32.1 4.1 2.4 2 2 0 2 2 2 1 F-box-like FAST_1 PF06743.15 EIM92140.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 1 GDI PF00996.18 EIM92141.1 - 7.6e-220 729.9 0.0 8.7e-220 729.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rap1-DNA-bind PF09197.10 EIM92142.1 - 0.0028 18.2 0.1 2.3 8.9 0.0 2.8 2 0 0 2 2 2 2 Rap1, DNA-binding Aldedh PF00171.22 EIM92143.1 - 1.3e-128 429.4 0.2 1.5e-128 429.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM92143.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) LMWPc PF01451.21 EIM92144.1 - 1.2e-38 132.7 0.0 1.3e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SH3BGR PF04908.15 EIM92145.1 - 1.8e-14 53.7 0.0 1.8e-14 53.7 0.0 2.7 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein adh_short_C2 PF13561.6 EIM92146.1 - 8.1e-46 156.5 0.1 1.3e-45 155.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM92146.1 - 1.3e-42 145.4 0.0 2.2e-42 144.7 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM92146.1 - 1.2e-08 35.0 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1611 PF07755.11 EIM92146.1 - 0.037 13.3 0.2 0.99 8.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain THF_DHG_CYH_C PF02882.19 EIM92146.1 - 0.079 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Seipin PF06775.14 EIM92147.1 - 3.6e-22 79.5 0.0 3e-21 76.4 0.0 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) MgtE PF01769.16 EIM92147.1 - 0.063 13.7 2.3 0.12 12.8 0.3 2.2 2 0 0 2 2 2 0 Divalent cation transporter DUF3328 PF11807.8 EIM92147.1 - 0.15 11.8 0.3 0.3 10.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) UPF0183 PF03676.14 EIM92148.1 - 0.16 11.2 0.1 1.7 7.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0183) Fungal_trans PF04082.18 EIM92150.1 - 2.8e-10 39.7 0.1 4.8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM92150.1 - 2.5e-06 27.5 13.9 4.5e-06 26.7 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GreA_GreB_N PF03449.15 EIM92150.1 - 0.049 13.8 0.4 0.092 12.9 0.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Fungal_trans PF04082.18 EIM92151.1 - 3.5e-06 26.2 0.1 3.9e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.22 EIM92153.1 - 3.5e-54 182.8 0.0 4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM92153.1 - 6.5e-22 78.0 0.0 9.1e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM92153.1 - 2.3e-07 30.4 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family His_Phos_1 PF00300.22 EIM92154.1 - 2.1e-40 138.5 0.0 2.7e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Filament PF00038.21 EIM92155.1 - 7.6e-05 22.4 29.7 7.6e-05 22.4 29.7 4.5 1 1 3 4 4 4 3 Intermediate filament protein TMF_TATA_bd PF12325.8 EIM92155.1 - 0.00014 22.0 6.9 0.00014 22.0 6.9 9.9 1 1 9 11 11 11 2 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 EIM92155.1 - 0.0014 19.0 6.1 0.012 16.0 1.4 11.4 9 2 5 14 14 14 2 Flagella accessory protein C (FlaC) EzrA PF06160.12 EIM92155.1 - 0.0027 16.0 17.7 0.0027 16.0 17.7 6.0 3 2 3 6 6 6 4 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 EIM92155.1 - 0.0027 18.3 9.7 0.0027 18.3 9.7 10.1 3 2 7 11 11 11 2 Clathrin-binding domain of Huntingtin-interacting protein 1 HAUS-augmin3 PF14932.6 EIM92155.1 - 0.0072 15.9 19.1 0.0072 15.9 19.1 7.8 1 1 8 9 9 9 2 HAUS augmin-like complex subunit 3 Lectin_N PF03954.14 EIM92155.1 - 0.0076 16.0 2.1 0.0076 16.0 2.1 8.0 4 3 5 9 9 9 2 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EIM92155.1 - 0.25 11.4 67.6 0.3 11.1 5.1 7.7 4 2 4 8 8 8 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EIM92155.1 - 0.97 8.3 139.7 0.055 12.4 20.9 6.1 1 1 6 7 7 7 0 Spc7 kinetochore protein Mito_carr PF00153.27 EIM92156.1 - 6.7e-31 106.1 7.3 4e-16 58.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ketoacyl-synt PF00109.26 EIM92157.1 - 2.4e-53 181.3 0.0 4e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EIM92157.1 - 1.3e-31 109.9 0.0 2.4e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EIM92157.1 - 2.3e-31 109.5 0.0 3.8e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EIM92157.1 - 7.5e-30 104.2 0.0 2.8e-29 102.3 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EIM92157.1 - 1.7e-17 63.5 0.0 1.6e-16 60.4 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EIM92157.1 - 3e-13 50.4 0.0 6.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 EIM92157.1 - 8.4e-12 45.5 0.0 2.4e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EIM92157.1 - 2e-06 28.0 0.2 9.8e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 EIM92157.1 - 5.6e-05 22.9 1.7 0.00011 21.9 0.7 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EIM92157.1 - 0.0043 16.4 0.2 0.008 15.6 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.16 EIM92159.1 - 5.4e-19 68.3 48.8 5.8e-19 68.2 39.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ArAE_2_N PF10337.9 EIM92159.1 - 0.24 10.4 1.8 1.2 8.1 1.8 2.0 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal NAD_binding_4 PF07993.12 EIM92160.1 - 2.4e-30 105.6 0.0 3.9e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EIM92160.1 - 6.2e-28 97.5 0.1 3.4e-27 95.1 0.1 2.0 1 1 1 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EIM92160.1 - 1.7e-09 37.5 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EIM92160.1 - 5e-05 23.6 0.1 0.00072 19.9 0.0 2.9 2 1 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 EIM92160.1 - 0.16 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 KR domain Mpv17_PMP22 PF04117.12 EIM92161.1 - 2.1e-07 31.1 1.0 2.1e-07 31.1 1.0 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family MOSC PF03473.17 EIM92162.1 - 4e-18 65.7 0.0 6.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EIM92162.1 - 8.5e-17 61.1 0.0 1.4e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain FTR_C PF02741.15 EIM92162.1 - 0.0079 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FTR, proximal lobe LCCL PF03815.19 EIM92163.1 - 2.1e-13 50.2 0.0 3.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF3094 PF11293.8 EIM92163.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) RRP7 PF12923.7 EIM92164.1 - 0.046 13.8 2.6 0.15 12.2 2.6 2.0 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain WW PF00397.26 EIM92165.1 - 0.0078 16.3 1.8 0.0078 16.3 1.8 2.4 2 0 0 2 2 2 1 WW domain DUF3435 PF11917.8 EIM92165.1 - 0.051 12.5 4.3 0.058 12.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) MHB PF16525.5 EIM92165.1 - 0.13 12.6 0.1 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 Haemophore, haem-binding TRAPPC-Trs85 PF12739.7 EIM92166.1 - 6.4e-30 104.4 0.0 6.7e-25 87.9 0.0 2.2 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 EIM92166.1 - 0.014 12.8 0.0 0.02 12.3 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit PALP PF00291.25 EIM92167.1 - 9.7e-63 212.3 0.0 1.1e-62 212.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_3 PF07859.13 EIM92168.1 - 6.8e-46 156.8 0.0 8.8e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EIM92168.1 - 0.0051 15.8 0.1 0.013 14.4 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EIM92168.1 - 0.037 13.5 0.0 1.2 8.5 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family Exo_endo_phos PF03372.23 EIM92169.1 - 3.2e-23 82.5 0.0 3.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyridox_ox_2 PF12900.7 EIM92170.1 - 2.2e-29 102.3 0.0 3.1e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4139 PF13598.6 EIM92171.1 - 2.7e-30 105.6 0.0 6.4e-30 104.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EIM92171.1 - 4.8e-12 46.2 8.1 2.2e-10 40.9 0.1 3.8 4 0 0 4 4 4 2 N-terminal domain of unknown function (DUF4140) CREPT PF16566.5 EIM92171.1 - 0.0044 17.2 1.3 0.009 16.2 1.3 1.4 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DivIVA PF05103.13 EIM92171.1 - 0.011 15.8 1.6 0.023 14.8 1.6 1.5 1 0 0 1 1 1 0 DivIVA protein DUF1465 PF07323.12 EIM92171.1 - 0.022 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) CCDC-167 PF15188.6 EIM92171.1 - 0.082 13.3 4.5 0.11 12.8 1.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Csm1_N PF18504.1 EIM92171.1 - 0.36 11.2 6.1 17 5.9 3.2 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain Fungal_TACC PF12709.7 EIM92171.1 - 2 8.9 6.2 3.7 8.1 2.4 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 EIM92171.1 - 2.2 8.8 8.8 0.23 11.9 3.6 2.0 3 0 0 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 EIM92171.1 - 7 7.2 8.2 1.1 9.8 3.7 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region APG12 PF04110.13 EIM92172.1 - 3.6e-28 97.8 0.1 4e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Vta1 PF04652.16 EIM92174.1 - 5.7e-43 146.4 0.1 6.4e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Vta1 like adh_short_C2 PF13561.6 EIM92175.1 - 4.4e-54 183.5 0.0 5.3e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM92175.1 - 2.8e-38 131.3 0.0 3.6e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM92175.1 - 1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM92175.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Arrestin_N PF00339.29 EIM92177.1 - 0.00024 21.2 0.0 0.00056 20.0 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Caenor_Her-1 PF09232.10 EIM92177.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 FR47 PF08445.10 EIM92178.1 - 5.2e-10 39.2 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EIM92178.1 - 7.9e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM92178.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM92178.1 - 1.3e-06 28.8 0.0 2.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM92178.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EIM92178.1 - 0.0026 17.7 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 EIM92178.1 - 0.0096 16.6 0.0 0.016 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EIM92178.1 - 0.052 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EIM92178.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RNase_P_pop3 PF08228.11 EIM92180.1 - 2.2e-14 53.8 0.0 3.5e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 RNase P subunit Pop3 dCMP_cyt_deam_1 PF00383.23 EIM92181.1 - 9.6e-27 92.8 0.8 1.4e-26 92.3 0.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIM92181.1 - 1.9e-13 50.4 0.1 2.9e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase MBD PF01429.19 EIM92181.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain HEAT PF02985.22 EIM92182.1 - 0.0012 18.9 3.1 1.1 9.7 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 EIM92182.1 - 0.26 11.8 4.2 12 6.6 0.2 4.4 4 0 0 4 4 4 0 HEAT-like repeat Chorismate_bind PF00425.18 EIM92183.1 - 9.2e-64 215.5 0.0 3.9e-63 213.4 0.0 1.9 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EIM92183.1 - 4.5e-29 101.6 0.0 6.7e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EIM92183.1 - 4.8e-17 62.5 0.0 2.1e-16 60.4 0.0 2.0 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EIM92183.1 - 8.8e-06 25.6 1.2 3.7e-05 23.6 1.2 1.8 1 1 0 1 1 1 1 Peptidase C26 DIOX_N PF14226.6 EIM92184.1 - 0.00081 20.1 0.0 0.0015 19.3 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIM92184.1 - 0.0033 17.9 0.0 0.0057 17.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pro_isomerase PF00160.21 EIM92185.1 - 6.6e-46 156.5 0.6 7.3e-46 156.3 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UQ_con PF00179.26 EIM92186.1 - 2e-39 134.5 0.1 2.5e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIM92186.1 - 0.0062 16.2 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EIM92186.1 - 0.04 13.8 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Nop52 PF05997.12 EIM92188.1 - 2.1e-74 249.9 0.0 3e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 EIM92188.1 - 0.00013 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II RabGAP-TBC PF00566.18 EIM92189.1 - 2e-27 96.3 0.0 3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EIM92189.1 - 0.0024 16.2 0.8 0.0032 15.8 0.8 1.0 1 0 0 1 1 1 1 SBE2, cell-wall formation DUF737 PF05300.11 EIM92189.1 - 0.09 13.1 1.2 0.14 12.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) GCP_C_terminal PF04130.13 EIM92190.1 - 3.9e-28 98.8 0.0 7.3e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EIM92190.1 - 2.1e-22 80.1 0.2 1e-20 74.6 0.2 2.3 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal I-set PF07679.16 EIM92191.1 - 0.0021 18.1 0.0 1.6 8.9 0.0 4.2 5 0 0 5 5 5 1 Immunoglobulin I-set domain Serglycin PF04360.12 EIM92191.1 - 0.013 15.4 0.5 0.028 14.4 0.5 1.4 1 0 0 1 1 1 0 Serglycin Importin_rep_6 PF18829.1 EIM92191.1 - 0.28 11.3 0.8 0.56 10.4 0.8 1.4 1 0 0 1 1 1 0 Importin repeat 6 NOA36 PF06524.12 EIM92191.1 - 2 7.6 4.1 3.3 7.0 4.1 1.2 1 0 0 1 1 1 0 NOA36 protein Thioredoxin PF00085.20 EIM92192.1 - 3.4e-25 88.0 0.0 4.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIM92192.1 - 7.5e-07 29.6 0.1 6.9e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIM92192.1 - 2.3e-05 24.6 0.0 0.0036 17.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EIM92192.1 - 0.00053 19.9 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EIM92192.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EIM92192.1 - 0.0021 17.8 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EIM92192.1 - 0.013 15.6 0.1 0.029 14.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like DUF2847 PF11009.8 EIM92192.1 - 0.02 14.8 0.1 0.071 13.0 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2847) Redoxin PF08534.10 EIM92192.1 - 0.024 14.4 0.2 0.076 12.7 0.1 1.6 1 1 1 2 2 2 0 Redoxin TraF PF13728.6 EIM92192.1 - 0.066 13.0 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein CENP-T_C PF15511.6 EIM92193.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EIM92193.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EIM92193.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EIM92193.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM92193.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EIM92193.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit F-box-like PF12937.7 EIM92194.1 - 1.2e-05 25.1 1.2 3.3e-05 23.7 1.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIM92194.1 - 9.2e-05 22.2 1.3 0.00034 20.4 0.8 2.3 2 0 0 2 2 2 1 F-box domain FtsX PF02687.21 EIM92195.1 - 0.38 11.2 2.9 0.74 10.3 0.1 2.4 1 1 1 2 2 2 0 FtsX-like permease family NUFIP1 PF10453.9 EIM92196.1 - 2.4e-19 68.9 1.7 6e-19 67.6 1.7 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Pet100 PF09803.9 EIM92196.1 - 0.12 12.9 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 Pet100 KH_1 PF00013.29 EIM92197.1 - 4.6e-41 138.5 8.1 3.5e-16 58.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EIM92197.1 - 5.3e-11 42.2 1.7 0.00057 19.7 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 EIM92197.1 - 1e-08 34.9 5.5 0.061 13.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EIM92197.1 - 2.6e-05 24.2 3.4 0.085 13.0 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Fungal_trans PF04082.18 EIM92198.1 - 8.5e-33 113.5 0.0 1.6e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM92198.1 - 5.1e-07 29.7 9.9 9.7e-07 28.8 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M16_C PF05193.21 EIM92199.1 - 1e-15 58.2 0.0 2.2e-10 40.9 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EIM92199.1 - 5.2e-10 39.5 0.0 4.4e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Complex1_LYR_2 PF13233.6 EIM92199.1 - 0.21 12.4 0.3 11 6.8 0.0 3.1 3 0 0 3 3 3 0 Complex1_LYR-like zf-CCCH PF00642.24 EIM92200.1 - 4.2e-19 68.0 24.6 2.5e-05 24.0 0.6 4.7 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIM92200.1 - 6.5e-14 51.5 31.0 1e-06 28.6 2.1 4.9 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EIM92200.1 - 4e-08 33.9 20.6 0.00039 21.1 0.3 5.0 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 EIM92200.1 - 2.5e-05 23.9 0.4 2.5e-05 23.9 0.4 4.2 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCHC PF00098.23 EIM92200.1 - 0.00037 20.4 3.7 0.00037 20.4 3.7 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 EIM92200.1 - 0.001 19.5 30.0 0.0085 16.5 0.3 5.3 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC_3 PF13917.6 EIM92200.1 - 0.0046 16.9 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_3 PF15663.5 EIM92200.1 - 4.9 7.4 16.2 2.7 8.3 0.4 3.4 2 1 1 3 3 3 0 Zinc-finger containing family UPF0047 PF01894.17 EIM92201.1 - 2.2e-38 130.9 0.0 2.6e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.18 EIM92202.1 - 1.1e-07 31.2 0.2 2.2e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM92202.1 - 1.2e-06 28.5 9.2 2.7e-06 27.4 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2457 PF10446.9 EIM92202.1 - 0.19 10.8 5.9 0.29 10.3 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SRP-alpha_N PF04086.13 EIM92203.1 - 0.57 10.0 15.8 0.72 9.7 15.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SPX PF03105.19 EIM92203.1 - 1.7 8.4 21.4 2.2 8.1 21.4 1.2 1 0 0 1 1 1 0 SPX domain SAPS PF04499.15 EIM92203.1 - 6.4 5.4 8.5 8.6 5.0 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RhoGEF PF00621.20 EIM92204.1 - 4.4e-14 53.1 0.0 1.2e-13 51.7 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain MMR_HSR1 PF01926.23 EIM92205.1 - 1.7e-14 53.9 0.0 4.6e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM92205.1 - 2.2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIM92205.1 - 0.0007 19.5 0.0 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EIM92205.1 - 0.018 15.1 2.0 0.52 10.3 0.2 3.1 2 1 1 3 3 3 0 Dynamin family FUSC PF04632.12 EIM92205.1 - 0.081 11.5 3.6 0.61 8.5 0.4 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family ParE_toxin PF05016.15 EIM92205.1 - 0.16 12.6 0.1 0.4 11.3 0.1 1.6 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Pyr_redox_2 PF07992.14 EIM92206.1 - 1e-33 116.8 0.4 1.4e-33 116.4 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIM92206.1 - 3.8e-13 49.8 0.1 2.5e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIM92206.1 - 1.4e-05 25.1 0.1 0.28 11.1 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EIM92206.1 - 0.00051 19.7 2.5 0.91 9.0 0.2 3.2 1 1 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EIM92206.1 - 0.081 12.2 0.1 1.3 8.2 0.0 2.0 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Methyltransf_25 PF13649.6 EIM92207.1 - 2.1e-16 60.4 0.0 3.9e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM92207.1 - 6.9e-14 52.3 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIM92207.1 - 1.7e-11 44.2 0.0 3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIM92207.1 - 4.3e-09 36.0 0.0 6.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EIM92207.1 - 6.2e-08 32.6 0.0 1.9e-07 31.0 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EIM92207.1 - 1.3e-06 27.9 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EIM92207.1 - 2.7e-06 28.1 0.0 4.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIM92207.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EIM92207.1 - 0.0012 18.4 0.0 0.04 13.4 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 EIM92207.1 - 0.0036 15.9 0.0 0.0063 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 EIM92207.1 - 0.0054 16.1 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EIM92207.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EIM92207.1 - 0.12 12.2 0.0 0.54 10.1 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase WD40 PF00400.32 EIM92208.1 - 7.1e-20 71.0 5.5 0.0015 19.3 0.0 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92208.1 - 8.6e-05 22.8 0.0 4.6 7.6 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 EIM92209.1 - 3.9e-10 39.4 0.1 8.1e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EIM92209.1 - 0.043 13.7 0.1 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 EIM92210.1 - 1.7e-15 56.6 0.1 4.2e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EIM92210.1 - 0.00019 21.2 0.2 0.00047 20.0 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain F-box-like PF12937.7 EIM92211.1 - 1.1e-07 31.6 0.1 2.5e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM92211.1 - 0.0005 20.4 0.5 0.0075 16.7 0.2 3.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIM92211.1 - 0.1 12.4 1.6 1.4 8.8 0.6 3.2 3 1 0 3 3 3 0 Leucine rich repeat PB1 PF00564.24 EIM92212.1 - 7.2e-08 32.3 1.7 1.5e-07 31.3 0.0 2.4 3 0 0 3 3 3 1 PB1 domain DUF3987 PF13148.6 EIM92212.1 - 4.9 6.0 10.2 1.1 8.2 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) KfrA_N PF11740.8 EIM92212.1 - 6.9 7.4 12.5 18 6.1 4.3 2.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Aldo_ket_red PF00248.21 EIM92213.1 - 1.6e-40 139.2 0.0 2.1e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPT PF03151.16 EIM92216.1 - 7e-10 38.7 22.1 8.7e-10 38.4 22.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EIM92216.1 - 4.4e-08 33.4 35.7 0.00014 22.1 16.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family O-FucT PF10250.9 EIM92217.1 - 1.8e-12 47.7 0.0 8.1e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ApbA_C PF08546.11 EIM92218.1 - 6e-31 107.2 0.1 1.1e-30 106.4 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EIM92218.1 - 4.1e-21 75.2 0.5 1.9e-19 69.8 0.4 2.5 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DUF1741 PF08427.10 EIM92219.1 - 7.2e-34 117.5 2.5 3.4e-33 115.2 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) F-box-like PF12937.7 EIM92220.1 - 2.9e-08 33.5 1.2 7.2e-08 32.2 1.2 1.7 1 0 0 1 1 1 1 F-box-like GDC-P PF02347.16 EIM92221.1 - 1.6e-179 597.3 0.0 1.3e-168 561.3 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EIM92221.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase SecE PF00584.20 EIM92222.1 - 3.7e-15 55.6 0.0 4.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.10 EIM92222.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) PPR_2 PF13041.6 EIM92223.1 - 3.5e-09 36.7 0.2 0.11 12.7 0.0 6.7 7 1 1 8 8 8 3 PPR repeat family PPR PF01535.20 EIM92223.1 - 0.0006 19.9 1.2 23 5.5 0.0 5.2 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 EIM92223.1 - 0.02 15.0 0.0 25 5.0 0.0 3.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Vps51 PF08700.11 EIM92224.1 - 9.8e-10 38.4 0.0 4e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 EIM92224.1 - 0.11 12.3 2.9 0.38 10.5 0.1 2.9 4 0 0 4 4 4 0 Exocyst complex component Sec5 Apolipoprotein PF01442.18 EIM92224.1 - 3.7 7.4 8.6 2.6 7.9 0.3 3.4 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF1751 PF08551.10 EIM92225.1 - 3.3e-22 78.9 3.5 3.3e-22 78.9 3.5 2.0 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EIM92225.1 - 0.026 14.5 7.8 0.064 13.3 7.8 1.6 1 1 0 1 1 1 0 Rhomboid family Ribosomal_60s PF00428.19 EIM92225.1 - 4.1 8.1 6.8 4 8.1 5.2 1.7 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF1754 PF08555.10 EIM92226.1 - 3.1e-13 50.3 1.1 5.6e-13 49.5 1.1 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.6 EIM92226.1 - 0.0084 15.5 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) WSD PF15613.6 EIM92227.1 - 0.0068 16.9 2.0 0.036 14.5 1.9 2.3 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF4746 PF15928.5 EIM92227.1 - 0.15 11.4 5.1 0.25 10.7 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) APG6_N PF17675.1 EIM92227.1 - 1.7 9.2 8.9 2.9 8.4 8.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Peptidase_M3 PF01432.20 EIM92228.1 - 1.7e-129 433.1 0.0 2.2e-129 432.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EIM92228.1 - 0.03 14.6 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Effector protein Mating_N PF12731.7 EIM92229.1 - 1.5e-07 31.4 0.4 2.8e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox_KN PF05920.11 EIM92231.1 - 2.8e-06 27.1 0.0 8.3e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.7 EIM92231.1 - 3e-05 24.0 3.3 0.00015 21.8 0.8 2.4 1 1 1 2 2 2 2 Mating-type protein beta 1 Aldo_ket_red PF00248.21 EIM92234.1 - 0.0058 15.9 0.0 0.0061 15.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ParA PF10609.9 EIM92235.1 - 2e-90 302.6 0.0 2.6e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EIM92235.1 - 1.6e-08 34.7 0.0 3.6e-07 30.3 0.0 2.5 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EIM92235.1 - 4.6e-06 26.0 0.4 0.00097 18.4 0.2 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 EIM92235.1 - 1.4e-05 25.1 0.0 0.0052 16.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EIM92235.1 - 1.9e-05 24.1 0.0 9.8e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 EIM92235.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_22 PF13401.6 EIM92235.1 - 0.066 13.5 0.1 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_26 PF13500.6 EIM92235.1 - 0.074 12.9 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EIM92235.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EIM92235.1 - 0.3 11.4 1.2 0.58 10.5 0.3 1.8 2 1 0 2 2 2 0 AAA ATPase domain RRM_1 PF00076.22 EIM92238.1 - 2.3e-11 43.4 0.0 1.9e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIM92238.1 - 6.7e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb6 PF01192.22 EIM92239.1 - 1.2e-15 57.1 0.2 1.5e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.17 EIM92240.1 - 1.3e-33 116.4 0.0 5e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Sir2 family Ribonuclease_T2 PF00445.18 EIM92241.1 - 1.7e-41 142.4 0.1 2.4e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family EthD PF07110.11 EIM92242.1 - 1.2e-07 32.8 0.2 0.0024 19.0 0.0 2.3 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 EIM92242.1 - 0.00066 20.1 0.1 0.11 13.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) ABM PF03992.16 EIM92242.1 - 0.022 14.8 0.0 0.054 13.6 0.0 1.7 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Myb_DNA-bind_7 PF15963.5 EIM92243.1 - 4.4e-21 74.6 0.0 9.3e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EIM92243.1 - 3.5e-07 30.3 0.0 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIM92243.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rep_fac_C PF08542.11 EIM92244.1 - 1.5e-25 89.4 0.0 3.5e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EIM92244.1 - 1.3e-12 47.9 0.0 2.8e-10 40.2 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EIM92244.1 - 2.4e-12 47.4 0.0 4.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EIM92244.1 - 1.3e-06 28.5 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM92244.1 - 1.9e-06 28.4 0.0 0.00016 22.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM92244.1 - 1.3e-05 25.5 0.1 0.005 17.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIM92244.1 - 6.3e-05 22.8 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EIM92244.1 - 7.6e-05 22.6 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EIM92244.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 EIM92244.1 - 0.00047 20.1 0.0 0.00095 19.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EIM92244.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EIM92244.1 - 0.0012 18.3 0.0 0.015 14.7 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EIM92244.1 - 0.0052 15.8 0.0 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EIM92244.1 - 0.0081 16.5 0.2 0.21 12.0 0.1 2.8 2 1 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 EIM92244.1 - 0.011 15.7 0.1 0.044 13.7 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_assoc_2 PF16193.5 EIM92244.1 - 0.02 15.2 0.0 0.057 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain AAA_24 PF13479.6 EIM92244.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EIM92244.1 - 0.031 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EIM92244.1 - 0.051 13.9 0.2 0.29 11.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EIM92244.1 - 0.055 12.9 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 EIM92244.1 - 0.16 11.6 0.1 0.34 10.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIM92244.1 - 0.18 12.3 0.0 0.41 11.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter tRNA-synt_2b PF00587.25 EIM92245.1 - 1.5e-21 77.2 0.0 3.2e-21 76.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EIM92245.1 - 7.7e-08 32.5 0.9 7.7e-08 32.5 0.9 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.21 EIM92245.1 - 0.2 12.2 2.2 2.7 8.5 0.7 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF5320 PF17253.2 EIM92245.1 - 0.67 11.1 2.8 4.3 8.5 0.6 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5320) VHS PF00790.19 EIM92246.1 - 1.8e-26 92.7 0.0 4e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EIM92246.1 - 1.3e-09 38.2 0.8 2.9e-08 33.9 2.0 2.3 2 0 0 2 2 2 1 GAT domain NARP1 PF12569.8 EIM92246.1 - 0.15 10.9 20.6 1.1 8.1 0.6 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Pectate_lyase_3 PF12708.7 EIM92247.1 - 1.7e-100 335.3 16.3 1.1e-84 283.6 6.6 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EIM92247.1 - 2.9e-07 30.1 1.1 0.013 15.2 0.4 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Utp11 PF03998.13 EIM92248.1 - 3.9e-75 252.9 16.4 4.5e-75 252.7 16.4 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EIM92248.1 - 0.027 13.8 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Nucleo_P87 PF07267.11 EIM92248.1 - 0.69 8.7 4.0 0.7 8.7 3.1 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NUFIP1 PF10453.9 EIM92248.1 - 5.4 6.9 7.7 20 5.1 1.9 3.5 3 0 0 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Focadhesin PF11229.8 EIM92249.1 - 0.091 11.0 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Focadhesin PI-PLC-X PF00388.19 EIM92250.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF512 PF04459.12 EIM92250.1 - 0.048 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Sigma54_AID PF00309.20 EIM92250.1 - 0.15 12.0 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) EF-hand_6 PF13405.6 EIM92251.1 - 1e-10 40.6 3.3 1.3e-05 24.8 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EIM92251.1 - 8.2e-08 31.3 5.8 8.9e-06 24.9 0.2 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EIM92251.1 - 8.3e-07 29.4 5.8 6e-06 26.6 1.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EIM92251.1 - 0.0034 16.8 0.5 0.0034 16.8 0.5 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 EIM92251.1 - 0.048 14.0 0.1 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EIM92251.1 - 0.5 10.3 4.4 0.64 9.9 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair Amidohydro_1 PF01979.20 EIM92253.1 - 1.4e-36 126.5 0.0 1.7e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIM92253.1 - 1.2e-13 51.4 0.1 1.3e-05 24.9 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 EIM92253.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase Methyltransf_25 PF13649.6 EIM92254.1 - 0.011 16.4 0.0 0.12 13.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain zf-C2H2 PF00096.26 EIM92255.1 - 3.3e-09 36.7 17.3 0.00015 22.0 1.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EIM92255.1 - 0.00049 20.3 0.7 0.00049 20.3 0.7 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EIM92255.1 - 0.0017 19.0 1.5 0.0017 19.0 1.5 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 EIM92255.1 - 0.0019 18.5 0.7 0.0019 18.5 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EIM92255.1 - 0.0025 18.1 3.6 0.0025 18.1 3.6 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 EIM92255.1 - 0.23 11.4 2.0 0.48 10.4 2.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 EIM92255.1 - 0.24 12.0 15.7 0.14 12.8 0.5 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EIM92255.1 - 0.27 11.3 8.0 0.046 13.7 3.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Zap1_zf2 PF18217.1 EIM92255.1 - 3.3 7.8 11.8 3.6 7.7 1.6 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF3591 PF12157.8 EIM92256.1 - 7.3e-189 628.0 1.1 1.2e-188 627.3 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EIM92256.1 - 3.2e-05 23.7 2.5 6.5e-05 22.7 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 EIM92256.1 - 0.0019 18.3 0.2 0.0039 17.3 0.2 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain BCA_ABC_TP_C PF12399.8 EIM92256.1 - 0.049 13.6 0.6 0.095 12.7 0.6 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter zf-CCHC PF00098.23 EIM92256.1 - 0.28 11.3 2.5 0.5 10.5 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle PA28_beta PF02252.18 EIM92257.1 - 6e-59 197.9 1.1 6.8e-59 197.7 0.4 1.4 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 EIM92257.1 - 0.00048 20.1 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit WD40 PF00400.32 EIM92258.1 - 7.9e-16 58.2 15.6 2.6e-06 28.0 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EIM92258.1 - 2.1e-14 53.5 0.0 9.9e-14 51.4 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 EIM92258.1 - 0.00024 21.1 0.1 0.011 15.7 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RXT2_N PF08595.11 EIM92258.1 - 0.03 14.3 1.5 0.076 13.0 1.5 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal MAPEG PF01124.18 EIM92259.1 - 6.1e-16 58.5 0.0 6.9e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 MAPEG family BBS1 PF14779.6 EIM92259.1 - 0.047 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Borrelia_P83 PF05262.11 EIM92259.1 - 0.21 10.0 0.1 0.24 9.9 0.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Ion_trans PF00520.31 EIM92261.1 - 2.4 7.3 10.6 7.1 5.8 10.6 1.7 1 1 0 1 1 1 0 Ion transport protein CWC25 PF12542.8 EIM92262.1 - 9e-23 81.1 0.1 9e-23 81.1 0.1 4.2 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EIM92262.1 - 9.3e-14 51.3 12.4 9.3e-14 51.3 12.4 4.6 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR 3Beta_HSD PF01073.19 EIM92264.1 - 1.1e-11 44.3 0.0 3.8e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM92264.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM92264.1 - 2.4e-07 30.9 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EIM92264.1 - 4e-07 29.4 0.0 0.017 14.2 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 EIM92264.1 - 0.0074 15.9 0.1 0.017 14.7 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EIM92264.1 - 0.038 14.2 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CRM1_repeat_3 PF18787.1 EIM92264.1 - 0.056 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 MFS_1 PF07690.16 EIM92265.1 - 1.1e-49 169.2 25.4 1.1e-49 169.2 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM92265.1 - 2.5e-12 46.4 11.8 2.5e-12 46.4 11.8 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EIM92265.1 - 5.4e-09 35.0 2.9 9.8e-09 34.2 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EIM92265.1 - 2.9e-06 26.1 6.2 2.9e-06 26.1 6.2 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 EIM92265.1 - 0.00015 20.3 6.6 0.00015 20.3 6.6 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.8 EIM92265.1 - 0.0003 19.6 14.2 0.016 13.9 1.0 3.1 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 EIM92265.1 - 0.00083 18.3 10.3 0.0022 16.9 1.0 2.4 1 1 0 2 2 2 2 MFS_1 like family EptA_B_N PF08019.12 EIM92265.1 - 1.4 8.8 8.6 0.21 11.5 1.0 3.0 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Colicin_E5 PF12106.8 EIM92266.1 - 0.063 13.6 1.1 0.063 13.6 1.1 1.5 1 1 1 2 2 2 0 Colicin E5 ribonuclease domain CxC6 PF18721.1 EIM92267.1 - 7e-12 45.4 1.2 7e-12 45.4 1.2 1.6 1 1 1 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases HORMA PF02301.18 EIM92268.1 - 4.7e-11 42.7 0.1 7.6e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 HORMA domain PX PF00787.24 EIM92269.1 - 8.1e-20 70.9 0.3 3e-19 69.1 0.3 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EIM92269.1 - 4.1e-06 26.5 8.6 0.01 15.4 3.8 2.4 1 1 0 2 2 2 2 Vps5 C terminal like Sec34 PF04136.15 EIM92269.1 - 0.031 14.2 2.3 0.051 13.4 0.0 2.2 2 0 0 2 2 2 0 Sec34-like family Rubis-subs-bind PF09273.11 EIM92269.1 - 0.079 13.7 1.2 2.2 9.0 0.4 2.4 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding BAR PF03114.18 EIM92269.1 - 0.088 12.4 2.3 4.3 6.9 0.6 3.1 3 0 0 3 3 3 0 BAR domain Lung_7-TM_R PF06814.13 EIM92270.1 - 1.4e-61 208.3 14.8 1.8e-61 208.0 14.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4234 PF14018.6 EIM92270.1 - 4.2 7.6 7.2 0.36 11.0 1.6 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) DUF3671 PF12420.8 EIM92270.1 - 5.5 7.1 6.1 7.5 6.7 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function RNA_pol_Rpb2_6 PF00562.28 EIM92272.1 - 1.8e-126 422.3 0.1 3.3e-126 421.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EIM92272.1 - 3.1e-67 226.0 0.1 4.5e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EIM92272.1 - 2.2e-48 164.4 0.1 5.1e-48 163.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EIM92272.1 - 1e-32 112.3 0.1 2.4e-32 111.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EIM92272.1 - 2.5e-26 91.7 0.5 8.7e-26 90.0 0.5 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EIM92272.1 - 5.1e-26 90.6 0.1 1.5e-25 89.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EIM92272.1 - 4.8e-24 84.7 0.2 1.3e-23 83.3 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Git3 PF11710.8 EIM92273.1 - 9e-10 38.7 4.8 1.9e-09 37.6 4.8 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EIM92273.1 - 2.8e-06 26.9 1.7 4.2e-06 26.3 1.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 EIM92273.1 - 0.0011 18.9 0.5 0.0028 17.7 0.1 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Fungal_trans PF04082.18 EIM92274.1 - 1.1e-19 70.5 0.6 2e-19 69.7 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM92274.1 - 0.00021 21.3 9.0 0.00021 21.3 9.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fructosamin_kin PF03881.14 EIM92275.1 - 1.3e-62 211.6 0.0 1.6e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EIM92275.1 - 9.4e-08 32.3 0.0 4.7e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 EIM92276.1 - 2.4e-21 76.1 0.0 4.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 EIM92276.1 - 0.07 13.0 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MAPEG PF01124.18 EIM92277.1 - 1.1e-19 70.6 0.8 1.4e-19 70.3 0.8 1.0 1 0 0 1 1 1 1 MAPEG family DUF2427 PF10348.9 EIM92278.1 - 0.09 12.6 0.1 0.098 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Glyco_transf_8 PF01501.20 EIM92279.1 - 5.1e-19 68.8 0.0 2.2e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 CDC45 PF02724.14 EIM92279.1 - 7.8 4.7 9.6 11 4.1 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 EIM92280.1 - 0.41 10.5 3.0 0.84 9.5 3.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 EIM92280.1 - 2.6 7.4 7.9 4.4 6.6 7.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIM92280.1 - 5.3 5.1 9.2 7.6 4.6 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EIM92280.1 - 7.2 5.0 4.9 11 4.4 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ANTH PF07651.16 EIM92282.1 - 1.1e-72 244.4 0.0 1.1e-72 244.4 0.0 3.2 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EIM92282.1 - 2.7e-54 183.6 9.0 2.7e-54 183.6 9.0 5.9 5 2 1 6 6 6 1 I/LWEQ domain TcdB_N PF12918.7 EIM92282.1 - 0.0026 18.0 0.2 0.03 14.6 0.0 2.9 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain ENTH PF01417.20 EIM92282.1 - 0.0041 17.2 1.8 0.037 14.1 0.0 3.6 4 0 0 4 4 4 1 ENTH domain FAA_hydro_N_2 PF18288.1 EIM92282.1 - 0.021 15.2 1.1 0.4 11.1 0.4 3.5 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 SURF1 PF02104.15 EIM92283.1 - 1.6e-43 148.9 0.1 2.1e-43 148.6 0.1 1.1 1 0 0 1 1 1 1 SURF1 family SoDot-IcmSS PF16848.5 EIM92284.1 - 0.16 11.9 0.3 0.31 11.0 0.3 1.3 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative MFS_1 PF07690.16 EIM92287.1 - 4.6e-37 127.7 28.3 4.6e-37 127.7 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM92287.1 - 6.4e-13 48.4 10.3 6.4e-13 48.4 10.3 2.9 2 2 2 4 4 4 1 Sugar (and other) transporter Med7 PF05983.11 EIM92289.1 - 3.6e-52 177.2 2.0 4.3e-52 177.0 2.0 1.1 1 0 0 1 1 1 1 MED7 protein U3_assoc_6 PF08640.11 EIM92289.1 - 0.0022 18.0 0.2 3.4 7.8 0.0 2.5 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 AphA_like PF14557.6 EIM92289.1 - 0.021 14.6 0.6 0.036 13.8 0.6 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator CCDC-167 PF15188.6 EIM92289.1 - 0.067 13.5 1.5 0.14 12.5 1.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Pal1 PF08316.11 EIM92293.1 - 0.046 14.5 0.0 0.046 14.5 0.0 4.8 3 1 0 3 3 3 0 Pal1 cell morphology protein GARS_A PF01071.19 EIM92294.1 - 5.3e-80 267.8 0.0 8.4e-80 267.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EIM92294.1 - 7.8e-36 123.6 0.0 2.3e-35 122.0 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EIM92294.1 - 2.9e-33 114.5 0.0 7.6e-33 113.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EIM92294.1 - 3.5e-28 97.7 0.8 8.2e-28 96.5 0.8 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EIM92294.1 - 2.3e-14 53.8 3.7 1.7e-13 51.0 1.4 3.2 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 EIM92294.1 - 0.00013 21.6 0.1 0.00025 20.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EIM92294.1 - 0.0038 17.3 0.0 0.0094 16.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain NAD_Gly3P_dh_C PF07479.14 EIM92296.1 - 6.8e-49 165.8 0.1 9.9e-49 165.3 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EIM92296.1 - 5.3e-34 117.5 0.0 9.1e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EIM92296.1 - 4.1e-09 36.2 0.0 7.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EIM92296.1 - 1.4e-06 28.8 0.0 4.3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EIM92296.1 - 0.00044 20.5 0.0 0.00091 19.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 EIM92296.1 - 0.0092 16.5 0.0 9.4 6.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EIM92296.1 - 0.14 12.2 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SNARE PF05739.19 EIM92297.1 - 4.5e-11 42.6 0.3 1.2e-10 41.2 0.0 1.8 2 0 0 2 2 1 1 SNARE domain Syntaxin PF00804.25 EIM92297.1 - 1.1e-05 25.2 8.6 0.00016 21.4 0.2 2.3 2 0 0 2 2 2 2 Syntaxin DUF16 PF01519.16 EIM92297.1 - 0.015 15.8 9.6 0.032 14.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 EIM92297.1 - 0.016 15.6 1.5 0.016 15.6 1.5 2.0 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.9 EIM92297.1 - 0.017 15.4 5.7 0.13 12.6 0.1 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 EIM92297.1 - 0.097 11.7 5.7 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 EIM92297.1 - 0.13 12.9 0.4 0.13 12.9 0.4 3.0 3 1 1 4 4 3 0 SlyX Osmo_CC PF08946.10 EIM92297.1 - 0.51 10.6 3.4 1.7 9.0 0.1 3.0 3 1 0 3 3 3 0 Osmosensory transporter coiled coil NPV_P10 PF05531.12 EIM92297.1 - 0.68 10.4 11.9 0.23 11.9 3.7 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EIM92297.1 - 0.71 10.2 6.3 5.8 7.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) End3 PF12761.7 EIM92297.1 - 1.2 9.3 9.2 0.32 11.1 0.3 2.6 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF3450 PF11932.8 EIM92297.1 - 2.4 7.4 12.3 3 7.1 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EIM92297.1 - 2.6 8.2 12.4 6.1 7.0 1.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 EIM92297.1 - 2.6 8.1 15.3 2.8 8.0 5.2 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ISG65-75 PF11727.8 EIM92297.1 - 2.9 7.0 7.0 8.2 5.6 2.2 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.12 EIM92297.1 - 3.6 7.7 10.1 2.3 8.2 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 EIM92298.1 - 9.8e-10 38.1 0.0 2.5e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF720 PF05302.11 EIM92298.1 - 0.026 14.4 0.4 0.18 11.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF720) Bim_N PF06773.11 EIM92298.1 - 0.21 11.3 1.3 0.45 10.2 1.3 1.6 1 0 0 1 1 1 0 Bim protein N-terminus AMP-binding PF00501.28 EIM92300.1 - 1.4e-86 290.7 0.0 1.8e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIM92300.1 - 4.4e-18 66.0 0.9 1.6e-17 64.2 0.6 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MRP-S25 PF13741.6 EIM92301.1 - 4.9e-50 170.2 4.1 6.2e-48 163.3 4.1 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EIM92301.1 - 0.0093 16.2 0.8 0.047 14.0 0.7 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 PCI PF01399.27 EIM92302.1 - 5.9e-18 65.3 0.0 3e-17 63.0 0.0 2.2 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EIM92302.1 - 6.6e-05 22.9 0.3 0.0002 21.4 0.3 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_20 PF14561.6 EIM92302.1 - 0.023 15.0 1.4 4.5 7.7 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ApoB100_C PF12491.8 EIM92302.1 - 0.11 12.4 1.5 1.8 8.6 0.0 3.2 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal F-box-like PF12937.7 EIM92303.1 - 0.00094 19.0 0.0 0.03 14.2 0.0 2.8 2 0 0 2 2 2 1 F-box-like Drc1-Sld2 PF11719.8 EIM92305.1 - 1.2e-10 41.5 3.4 1.2e-10 41.5 3.4 2.8 2 1 0 2 2 2 1 DNA replication and checkpoint protein Abhydrolase_1 PF00561.20 EIM92308.1 - 1.2e-13 51.3 0.0 1.1e-12 48.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIM92308.1 - 1e-09 39.3 0.1 1.3e-09 39.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM92308.1 - 5.6e-06 25.8 0.0 0.0069 15.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EIM92308.1 - 0.00013 21.6 0.0 0.00049 19.7 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 EIM92308.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EIM92308.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EIM92308.1 - 0.035 13.9 0.1 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 EIM92308.1 - 0.093 12.9 0.0 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein SF3A2 PF16835.5 EIM92309.1 - 4.6e-37 126.3 0.1 6.8e-37 125.7 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EIM92309.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EIM92309.1 - 0.014 14.9 0.9 0.026 14.1 0.9 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 EIM92309.1 - 0.037 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein S1 PF00575.23 EIM92310.1 - 1.5e-53 179.0 24.0 5.2e-13 49.1 0.1 10.4 10 0 0 10 10 10 8 S1 RNA binding domain TPR_14 PF13428.6 EIM92310.1 - 3.6e-05 24.2 0.0 20 6.3 0.0 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EIM92310.1 - 0.00055 19.2 8.1 0.058 12.5 4.5 3.3 1 1 2 3 3 3 3 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 EIM92310.1 - 0.00061 20.3 0.0 3.2 8.3 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 EIM92310.1 - 0.0037 17.3 11.3 0.0074 16.3 0.1 3.5 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_21 PF09976.9 EIM92310.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF2110 PF09883.9 EIM92310.1 - 0.023 14.3 1.8 0.82 9.2 0.1 3.8 4 1 1 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2110) RNase_II_C_S1 PF18614.1 EIM92310.1 - 0.03 14.3 2.0 15 5.6 0.0 4.2 5 0 0 5 5 5 0 RNase II-type exonuclease C-terminal S1 domain Sel1 PF08238.12 EIM92310.1 - 0.047 14.4 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Sel1 repeat Kelch_3 PF13415.6 EIM92311.1 - 5.3e-24 84.0 13.9 3.2e-07 30.5 0.0 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EIM92311.1 - 1.8e-22 78.9 5.5 0.00023 21.1 0.0 5.9 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 EIM92311.1 - 9.3e-22 76.8 14.2 4.5e-05 23.4 0.0 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EIM92311.1 - 9.1e-19 66.8 8.2 0.0069 15.9 0.1 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EIM92311.1 - 9.5e-18 63.8 8.3 0.00085 19.5 1.6 6.5 3 2 2 5 5 5 5 Kelch motif Kelch_2 PF07646.15 EIM92311.1 - 5.5e-16 57.8 3.6 0.0012 18.7 1.3 6.1 5 1 0 5 5 5 5 Kelch motif Fez1 PF06818.15 EIM92311.1 - 0.00094 19.7 16.3 0.00094 19.7 16.3 7.0 3 1 4 7 7 7 1 Fez1 DUF2730 PF10805.8 EIM92311.1 - 0.11 12.6 23.3 1.1 9.3 0.9 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2730) zf-C2H2_6 PF13912.6 EIM92312.1 - 0.00058 19.8 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EIM92312.1 - 0.065 12.9 0.1 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 EIM92312.1 - 0.084 13.4 1.2 0.11 12.9 1.2 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EIM92312.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EIM92312.1 - 0.13 13.1 0.6 0.19 12.7 0.6 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Lgl_C PF08596.10 EIM92314.1 - 2.8e-34 118.5 0.0 1.2e-33 116.4 0.0 2.0 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EIM92314.1 - 2.5e-05 24.9 8.9 0.056 14.3 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92314.1 - 0.0003 21.0 0.0 0.66 10.3 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2358 PF10184.9 EIM92315.1 - 3.6e-05 24.0 0.0 6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EIM92315.1 - 0.014 16.1 0.0 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain SPX PF03105.19 EIM92315.1 - 0.017 15.0 0.9 0.022 14.7 0.9 1.1 1 0 0 1 1 1 0 SPX domain V-SNARE_C PF12352.8 EIM92316.1 - 7.1e-17 61.5 8.2 8.6e-17 61.2 0.9 3.4 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus APG6_N PF17675.1 EIM92316.1 - 0.00046 20.7 3.9 0.25 11.9 0.2 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region DUF4407 PF14362.6 EIM92316.1 - 0.00088 18.7 1.9 0.0011 18.4 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FAM184 PF15665.5 EIM92316.1 - 0.0083 15.9 1.1 0.028 14.2 1.1 1.8 1 1 0 1 1 1 1 Family with sequence similarity 184, A and B DUF148 PF02520.17 EIM92316.1 - 0.0091 16.1 1.0 0.031 14.4 0.6 2.0 1 1 1 2 2 2 1 Domain of unknown function DUF148 SHE3 PF17078.5 EIM92316.1 - 0.0096 15.7 3.3 0.019 14.7 3.2 1.6 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Sec20 PF03908.13 EIM92316.1 - 0.014 15.3 0.6 0.057 13.3 0.0 2.2 2 1 0 2 2 2 0 Sec20 Tektin PF03148.14 EIM92316.1 - 0.016 14.0 4.0 0.33 9.6 0.4 2.1 1 1 1 2 2 2 0 Tektin family DUF2203 PF09969.9 EIM92316.1 - 0.023 15.4 1.5 0.051 14.3 0.6 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) LXG PF04740.12 EIM92316.1 - 0.028 14.1 3.3 0.59 9.8 0.5 3.0 1 1 2 3 3 3 0 LXG domain of WXG superfamily Filament PF00038.21 EIM92316.1 - 0.029 14.0 3.6 0.067 12.8 3.1 1.7 1 1 1 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 EIM92316.1 - 0.03 14.3 2.3 5 7.2 0.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EIM92316.1 - 0.03 13.7 1.5 0.046 13.1 1.2 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med30 PF11315.8 EIM92316.1 - 0.033 14.4 0.8 0.16 12.1 0.1 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 Seryl_tRNA_N PF02403.22 EIM92316.1 - 0.068 13.4 0.7 1.9 8.7 0.0 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2730 PF10805.8 EIM92316.1 - 0.081 13.0 0.6 4.8 7.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Tropomyosin_1 PF12718.7 EIM92316.1 - 0.087 13.0 1.1 0.19 11.9 0.3 1.7 1 1 0 1 1 1 0 Tropomyosin like FlgN PF05130.12 EIM92316.1 - 0.097 13.2 2.0 0.17 12.4 1.3 1.9 1 1 0 1 1 1 0 FlgN protein Nup54 PF13874.6 EIM92316.1 - 0.13 12.4 2.5 0.48 10.5 2.5 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 GrpE PF01025.19 EIM92316.1 - 0.13 11.9 1.1 0.34 10.6 1.3 1.6 1 1 0 1 1 1 0 GrpE Goodbye PF17109.5 EIM92316.1 - 0.17 12.4 0.3 48 4.4 0.1 3.1 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain Muted PF14942.6 EIM92316.1 - 0.17 12.2 2.0 0.56 10.5 0.6 2.1 1 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein NPV_P10 PF05531.12 EIM92316.1 - 0.17 12.4 5.5 0.64 10.5 1.2 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 EIM92316.1 - 0.24 11.2 2.3 0.51 10.1 2.3 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 CorA PF01544.18 EIM92316.1 - 0.26 10.6 2.5 0.35 10.2 2.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.12 EIM92316.1 - 0.33 11.0 4.6 1.8 8.6 4.5 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EIM92316.1 - 0.51 10.6 4.1 0.55 10.5 0.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Snapin_Pallidin PF14712.6 EIM92316.1 - 0.6 10.6 5.5 13 6.3 2.7 3.0 2 1 0 2 2 2 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 EIM92316.1 - 0.63 10.1 5.6 2.7 8.1 0.6 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.15 EIM92316.1 - 0.71 10.3 4.0 1.2 9.6 2.2 2.4 3 1 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus TatD_DNase PF01026.21 EIM92317.1 - 6.8e-17 61.7 0.0 2.7e-16 59.7 0.0 1.8 1 1 0 1 1 1 1 TatD related DNase Met_10 PF02475.16 EIM92318.1 - 4.2e-70 235.6 0.0 1.2e-68 230.7 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein MethyltransfD12 PF02086.15 EIM92318.1 - 0.0015 18.3 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 EIM92318.1 - 0.019 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.7 EIM92318.1 - 0.13 12.2 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 EIM92319.1 - 2.5e-68 226.1 1.0 1.4e-22 79.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EIM92319.1 - 3.2e-15 56.3 4.8 5.4e-05 23.6 0.0 5.6 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 EIM92319.1 - 2.7e-13 48.4 4.3 6.9e-06 25.3 0.1 6.0 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 EIM92319.1 - 3.3e-13 48.4 4.3 6.5e-05 22.6 0.1 6.2 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.6 EIM92319.1 - 9.9e-09 34.9 1.5 0.015 15.2 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EIM92319.1 - 5.1e-06 25.8 7.8 0.00033 20.0 0.2 4.1 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 EIM92319.1 - 0.0057 17.0 0.7 2.6 8.4 0.0 4.0 5 0 0 5 5 5 1 EF-hand domain MoaC PF01967.21 EIM92320.1 - 6.5e-48 162.3 0.0 1.1e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EIM92320.1 - 1.5e-35 122.0 0.4 5.5e-35 120.1 0.0 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EIM92320.1 - 1.5e-26 93.7 0.0 3.4e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EIM92320.1 - 2.8e-07 30.9 0.0 6.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EIM92320.1 - 0.0012 18.9 0.0 0.0036 17.4 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Acetyltransf_10 PF13673.7 EIM92321.1 - 6.8e-07 29.3 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM92321.1 - 7.9e-07 29.0 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EIM92321.1 - 5e-06 26.7 0.0 8.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIM92321.1 - 3.7e-05 24.1 0.0 6.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIM92321.1 - 0.02 14.9 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EIM92321.1 - 0.026 14.0 0.0 0.063 12.7 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 EIM92321.1 - 0.071 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF953 PF06110.11 EIM92322.1 - 1.3e-18 66.7 0.0 1.4e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 EIM92322.1 - 0.02 14.8 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin NIPSNAP PF07978.13 EIM92323.1 - 4.9e-31 107.0 3.6 6.6e-25 87.3 0.3 2.2 2 0 0 2 2 2 2 NIPSNAP O-FucT PF10250.9 EIM92324.1 - 3.7e-06 26.9 0.0 8.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1664 PF07889.12 EIM92325.1 - 0.0055 16.8 108.6 0.17 11.9 2.3 13.2 9 4 1 12 12 12 7 Protein of unknown function (DUF1664) BRE1 PF08647.11 EIM92325.1 - 0.0074 16.3 11.4 0.0074 16.3 11.4 13.8 7 5 4 13 13 13 3 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 EIM92325.1 - 0.0084 16.1 10.0 0.0084 16.1 10.0 13.5 5 5 6 12 12 12 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.16 EIM92326.1 - 1.5e-44 152.4 36.2 1.6e-30 106.3 8.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EIM92326.1 - 2.8e-08 33.0 26.7 0.00038 19.4 7.2 3.0 2 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 EIM92326.1 - 1.5 7.0 9.2 0.071 11.4 1.2 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fapy_DNA_glyco PF01149.24 EIM92327.1 - 1.2e-29 103.3 0.1 2e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EIM92327.1 - 1.8e-18 66.3 0.0 5e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EIM92327.1 - 0.0012 17.7 0.0 0.0038 16.0 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 EIM92327.1 - 0.007 16.8 0.1 0.036 14.5 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein S13/S18 Metallophos_2 PF12850.7 EIM92327.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Utp12 PF04003.12 EIM92328.1 - 3.4e-23 82.0 0.0 6.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 EIM92328.1 - 3.3e-06 27.7 3.7 0.067 14.1 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92328.1 - 0.00031 21.0 1.0 0.39 11.1 0.3 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EIM92329.1 - 3.8e-76 255.9 0.0 5.2e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92329.1 - 2.9e-35 121.8 0.2 6e-35 120.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM92329.1 - 0.00024 20.2 0.0 0.0087 15.0 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIM92329.1 - 0.019 14.3 0.0 0.046 13.0 0.0 1.8 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EIM92329.1 - 0.23 11.4 0.0 0.23 11.4 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF3362 PF11842.8 EIM92331.1 - 0.057 13.7 0.1 0.057 13.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) WD40 PF00400.32 EIM92332.1 - 3.2e-45 151.2 11.0 1.4e-08 35.2 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EIM92332.1 - 1.6e-32 112.4 0.0 3e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EIM92332.1 - 8e-10 38.9 0.1 0.028 14.7 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM92332.1 - 3.1e-05 22.8 0.9 0.89 8.1 0.0 3.6 4 0 0 4 4 4 2 Nucleoporin Nup120/160 LisH PF08513.11 EIM92332.1 - 0.0017 18.2 0.1 0.0072 16.2 0.0 2.0 2 0 0 2 2 2 1 LisH eIF2A PF08662.11 EIM92332.1 - 0.0019 18.1 0.0 0.0062 16.4 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EIM92332.1 - 0.0037 15.9 0.0 0.0065 15.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EIM92332.1 - 0.049 12.6 0.0 0.76 8.7 0.0 2.5 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_N PF08240.12 EIM92333.1 - 2.1e-29 101.6 0.7 4e-29 100.7 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM92333.1 - 4.3e-13 49.4 0.1 5.2e-10 39.4 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EIM92333.1 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Met_10 PF02475.16 EIM92333.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 EIM92333.1 - 0.16 11.8 0.1 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EIM92333.1 - 0.16 12.7 0.0 0.56 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RSN1_7TM PF02714.15 EIM92334.1 - 3.4e-07 29.9 16.4 6e-07 29.0 16.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 EIM92334.1 - 0.00014 21.9 0.1 0.00037 20.6 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 EIM92334.1 - 0.0013 18.5 0.3 0.0013 18.5 0.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF2545 PF10810.8 EIM92334.1 - 0.019 15.1 0.5 0.073 13.2 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) Pox_A14 PF05767.12 EIM92334.1 - 0.3 11.3 1.9 1.2 9.4 1.9 2.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Metallophos PF00149.28 EIM92336.1 - 1.3e-11 45.4 0.9 2.2e-11 44.6 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM92336.1 - 0.045 13.9 2.2 4.3 7.5 2.2 2.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 EIM92337.1 - 0.00024 20.9 2.9 0.0016 18.3 2.9 2.3 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EIM92337.1 - 0.029 14.8 0.6 0.97 9.9 0.1 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) NUDE_C PF04880.13 EIM92341.1 - 7.1e-09 36.4 15.8 7.1e-09 36.4 15.8 6.3 3 2 4 7 7 2 1 NUDE protein, C-terminal conserved region ERM PF00769.19 EIM92341.1 - 0.00058 19.8 15.4 0.00058 19.8 15.4 2.4 1 1 1 2 2 2 1 Ezrin/radixin/moesin family PRKG1_interact PF15898.5 EIM92341.1 - 0.00082 20.2 9.4 0.00082 20.2 9.4 4.0 2 1 2 4 4 4 2 cGMP-dependent protein kinase interacting domain DUF2353 PF09789.9 EIM92341.1 - 0.12 11.7 27.0 0.042 13.2 12.3 3.1 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) TMF_TATA_bd PF12325.8 EIM92341.1 - 0.12 12.6 28.8 6.9 6.9 5.0 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding HIP1_clath_bdg PF16515.5 EIM92341.1 - 0.15 12.7 27.4 1.6 9.4 2.6 3.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 EIM92341.1 - 0.26 10.6 27.7 2.6 7.4 23.0 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DegS PF05384.11 EIM92341.1 - 0.28 10.7 18.3 0.073 12.5 2.5 3.1 2 1 1 3 3 3 0 Sensor protein DegS TPR_MLP1_2 PF07926.12 EIM92341.1 - 0.48 10.5 34.3 0.51 10.4 5.8 3.9 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EIM92341.1 - 0.63 8.9 30.9 0.47 9.3 15.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Leu_zip PF15294.6 EIM92341.1 - 0.84 9.1 24.6 2.2 7.7 13.0 2.3 1 1 1 2 2 2 0 Leucine zipper ZapB PF06005.12 EIM92341.1 - 1.3 9.5 33.2 0.037 14.5 3.9 4.0 2 1 2 4 4 4 0 Cell division protein ZapB APG6_N PF17675.1 EIM92341.1 - 3.7 8.1 35.7 0.65 10.5 18.5 3.4 1 1 3 4 4 4 0 Apg6 coiled-coil region ADIP PF11559.8 EIM92341.1 - 4.9 7.2 28.5 0.15 12.2 6.0 3.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding EXOSC1 PF10447.9 EIM92342.1 - 6e-18 65.5 1.4 6.7e-13 49.2 0.3 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 Malic_M PF03949.15 EIM92343.1 - 2.6e-89 298.9 0.0 3.4e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EIM92343.1 - 6.9e-65 218.2 0.0 1.1e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GST_N_2 PF13409.6 EIM92344.1 - 5.3e-23 81.1 0.0 9.6e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIM92344.1 - 2.8e-14 52.9 0.0 7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIM92344.1 - 1.5e-09 37.9 0.0 3.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIM92344.1 - 3.4e-05 23.9 0.0 6.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIM92344.1 - 4e-05 23.9 0.0 0.00066 20.0 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Peptidase_M22 PF00814.25 EIM92345.1 - 1.7e-82 277.2 0.0 2e-82 277.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EIM92345.1 - 0.031 13.9 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus Glyco_transf_8 PF01501.20 EIM92346.1 - 1.2e-19 70.9 0.0 5.9e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EIM92346.1 - 0.0048 16.3 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_transf_24 PF18404.1 EIM92346.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 DAO PF01266.24 EIM92347.1 - 3.6e-41 141.9 0.4 4.5e-41 141.6 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM92347.1 - 9.6e-06 25.7 0.9 2.7e-05 24.3 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIM92347.1 - 0.024 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIM92347.1 - 0.043 13.1 0.2 0.09 12.0 0.2 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EIM92347.1 - 0.052 13.5 1.2 1.6 8.7 0.3 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIM92347.1 - 0.074 12.1 0.2 0.087 11.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EIM92347.1 - 0.099 11.7 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Ribosomal_S28e PF01200.18 EIM92348.1 - 5.3e-32 109.6 1.8 5.9e-32 109.5 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PIP5K PF01504.18 EIM92349.1 - 4.3e-46 157.4 0.0 1e-37 129.9 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EIM92349.1 - 2.8e-28 98.8 0.0 4.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EIM92349.1 - 3.7e-16 59.0 12.1 3.7e-16 59.0 12.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.21 EIM92349.1 - 2.5 8.4 13.4 0.085 13.1 6.8 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PCI PF01399.27 EIM92350.1 - 1.4e-20 73.7 1.0 4.4e-20 72.2 0.9 2.0 1 1 0 1 1 1 1 PCI domain DUF3858 PF12970.7 EIM92350.1 - 0.043 13.8 0.3 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) DUF3626 PF12294.8 EIM92350.1 - 0.059 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) FeoC PF09012.10 EIM92350.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF5517 PF17639.2 EIM92350.1 - 0.26 11.6 6.4 0.2 12.0 1.0 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5517) MRP-L28 PF09812.9 EIM92351.1 - 1.1e-09 38.7 10.4 2.5e-09 37.5 4.2 2.4 2 1 1 3 3 3 2 Mitochondrial ribosomal protein L28 DUF1283 PF06932.11 EIM92351.1 - 0.085 13.1 0.6 0.14 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) Rsm22 PF09243.10 EIM92352.1 - 9.2e-45 153.0 0.0 2.8e-24 85.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.29 EIM92353.1 - 3e-26 92.5 0.0 4.5e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EIM92353.1 - 3.7e-13 49.6 0.4 6.6e-13 48.8 0.4 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein dsrm PF00035.26 EIM92354.1 - 2.1e-06 28.4 0.0 2.5e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 EIM92355.1 - 1.5e-11 44.8 0.0 2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif WD40 PF00400.32 EIM92356.1 - 1.7e-41 139.4 19.6 1.7e-07 31.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92356.1 - 5.2e-17 61.9 0.1 0.002 18.4 0.1 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIM92356.1 - 0.00032 19.8 0.7 2 7.3 0.0 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EIM92356.1 - 0.00038 20.4 0.0 0.36 10.7 0.0 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EIM92356.1 - 0.0025 17.2 0.0 0.81 8.9 0.0 3.3 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 EIM92356.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain CALCOCO1 PF07888.11 EIM92357.1 - 6e-05 22.1 94.3 0.003 16.5 31.5 3.2 1 1 2 3 3 3 3 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 EIM92357.1 - 0.00011 21.2 90.1 0.013 14.4 14.1 5.6 1 1 4 5 5 5 5 Spc7 kinetochore protein Tropomyosin PF00261.20 EIM92357.1 - 0.00033 20.1 41.8 0.00033 20.1 41.8 4.7 1 1 2 4 4 3 2 Tropomyosin Tropomyosin_1 PF12718.7 EIM92357.1 - 0.008 16.3 30.8 0.008 16.3 30.8 6.3 1 1 6 7 7 7 2 Tropomyosin like Uds1 PF15456.6 EIM92357.1 - 0.01 16.0 17.0 0.01 16.0 17.0 7.0 2 1 5 7 7 6 0 Up-regulated During Septation bZIP_1 PF00170.21 EIM92357.1 - 0.022 14.8 0.0 0.022 14.8 0.0 8.4 5 3 1 9 9 8 0 bZIP transcription factor ATG16 PF08614.11 EIM92357.1 - 0.044 14.0 112.0 0.78 9.9 4.0 6.4 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EIM92357.1 - 0.05 12.2 65.3 0.064 11.9 29.5 3.5 1 1 2 3 3 3 0 AAA domain APG6_N PF17675.1 EIM92357.1 - 0.12 12.9 103.2 1.2 9.7 22.5 7.1 1 1 6 7 7 7 0 Apg6 coiled-coil region DUF1664 PF07889.12 EIM92357.1 - 0.12 12.4 56.2 0.025 14.6 2.2 6.9 1 1 4 7 7 7 0 Protein of unknown function (DUF1664) MAD PF05557.13 EIM92357.1 - 0.14 10.5 87.7 0.79 8.0 24.2 3.6 1 1 3 4 4 4 0 Mitotic checkpoint protein ACT_6 PF13740.6 EIM92357.1 - 0.24 11.4 4.9 2 8.4 0.3 3.7 3 0 0 3 3 3 0 ACT domain PKcGMP_CC PF16808.5 EIM92357.1 - 0.26 11.2 0.0 0.26 11.2 0.0 8.6 9 0 0 9 9 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 EIM92357.1 - 0.29 10.4 73.7 1.1 8.5 0.5 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EIM92357.1 - 0.45 10.6 90.5 0.032 14.3 21.7 5.3 1 1 3 4 4 3 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EIM92357.1 - 1.3 8.0 76.6 0.35 9.9 14.8 4.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 EIM92357.1 - 1.4 8.4 87.5 0.23 11.0 5.2 6.5 1 1 4 6 6 6 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 EIM92357.1 - 8 6.5 102.0 4.8 7.2 18.0 8.2 1 1 5 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 EIM92357.1 - 8.3 6.7 19.5 18 5.6 1.1 6.6 6 0 0 6 6 6 0 Homeobox associated leucine zipper Hexapep PF00132.24 EIM92360.1 - 1.3e-08 34.2 17.6 0.015 15.0 0.2 4.4 3 2 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EIM92360.1 - 0.27 11.0 15.7 0.046 13.5 5.4 3.1 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase MMM1 PF10296.9 EIM92361.1 - 2e-11 43.6 0.0 6.1e-10 38.7 0.1 2.7 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 EIM92361.1 - 0.013 16.0 0.2 1.5 9.3 0.2 2.6 1 1 0 1 1 1 0 PH domain PH_9 PF15410.6 EIM92361.1 - 0.16 12.4 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Phage_GPL PF05926.11 EIM92363.1 - 0.02 14.9 0.2 0.038 14.0 0.2 1.4 1 0 0 1 1 1 0 Phage head completion protein (GPL) NCBP3 PF10309.9 EIM92364.1 - 2.2e-09 37.0 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 EIM92364.1 - 3.8e-05 23.6 0.0 5.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain SIKE PF05769.11 EIM92365.1 - 1.1e-08 35.2 8.2 1.1e-08 35.2 8.2 2.6 3 0 0 3 3 3 2 SIKE family Branch PF02485.21 EIM92365.1 - 0.061 12.8 0.6 0.11 12.0 0.6 1.3 1 0 0 1 1 1 0 Core-2/I-Branching enzyme DALR_1 PF05746.15 EIM92365.1 - 0.064 13.4 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 DALR anticodon binding domain NYD-SP28_assoc PF14775.6 EIM92365.1 - 0.1 12.7 5.5 0.52 10.4 2.1 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain Clathrin_lg_ch PF01086.17 EIM92365.1 - 0.12 12.4 0.0 0.12 12.4 0.0 3.0 3 0 0 3 3 3 0 Clathrin light chain SLY PF12485.8 EIM92365.1 - 1.2 9.8 0.0 1.2 9.8 0.0 2.5 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein PikAIV_N PF18605.1 EIM92365.1 - 1.3 8.6 8.2 3.2 7.4 0.2 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain V_ATPase_I PF01496.19 EIM92365.1 - 3.2 5.5 8.2 0.27 9.1 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EIM92365.1 - 6.7 7.4 12.0 2.9 8.6 3.8 3.3 2 2 0 3 3 3 0 Initiation control protein YabA F-box-like PF12937.7 EIM92366.1 - 1.7e-07 31.0 3.5 5.2e-07 29.5 2.2 2.6 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 EIM92367.1 - 1.2e-05 25.2 1.7 5e-05 23.1 1.7 2.2 1 1 0 1 1 1 1 F-box-like Sporozoite_P67 PF05642.11 EIM92369.1 - 4.2 5.3 8.1 7.2 4.6 8.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DSHCT PF08148.12 EIM92370.1 - 2e-52 177.1 0.5 3.9e-52 176.2 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EIM92370.1 - 1.4e-32 112.3 0.0 2.5e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EIM92370.1 - 1.4e-30 107.2 0.1 2.1e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EIM92370.1 - 2.1e-19 70.0 0.1 5.3e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIM92370.1 - 7.2e-07 29.4 0.1 3.5e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM92370.1 - 3e-05 24.3 0.0 8.4e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 EIM92370.1 - 0.078 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Ferritin_2 PF13668.6 EIM92371.1 - 4e-15 56.2 0.1 6.3e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Ist1 PF03398.14 EIM92372.1 - 7.7e-61 204.8 1.5 1e-60 204.4 1.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RasGEF PF00617.19 EIM92373.1 - 1.4e-38 132.8 0.0 2.3e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EIM92373.1 - 6.3e-17 61.7 0.0 1.5e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EIM92373.1 - 7.2e-16 57.5 0.2 1.8e-15 56.2 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EIM92373.1 - 8e-11 41.5 0.2 2.2e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EIM92373.1 - 4.8e-10 39.1 0.1 1.9e-09 37.2 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 EIM92373.1 - 0.25 11.6 0.5 0.63 10.4 0.5 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain PAP1 PF08601.10 EIM92373.1 - 1.6 8.4 7.1 3.1 7.4 7.1 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Ras PF00071.22 EIM92374.1 - 1e-59 200.8 0.1 1.2e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM92374.1 - 4.1e-36 123.8 0.0 5.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM92374.1 - 1.6e-13 50.5 0.1 1.9e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIM92374.1 - 1.6e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM92374.1 - 2.2e-06 27.7 0.1 0.02 14.8 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EIM92374.1 - 2.4e-05 24.0 0.0 4.8e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EIM92374.1 - 2.5e-05 23.7 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EIM92374.1 - 0.0092 16.4 0.2 0.024 15.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EIM92374.1 - 0.06 12.8 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein GbpA_2 PF18416.1 EIM92374.1 - 0.097 13.0 0.4 1.5 9.1 0.4 2.5 1 1 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 PP2C PF00481.21 EIM92375.1 - 1.7e-16 60.7 0.0 2.8e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EIM92375.1 - 1.8e-08 34.3 0.3 4.8e-08 32.9 0.3 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Aconitase_B_N PF11791.8 EIM92375.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Aconitate B N-terminal domain MbeB_N PF04837.12 EIM92375.1 - 0.24 11.7 0.1 0.24 11.7 0.1 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region polyprenyl_synt PF00348.17 EIM92377.1 - 4.2e-63 212.8 0.0 3.7e-58 196.6 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase DUF5429 PF17494.2 EIM92377.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5429) DUF3409 PF11889.8 EIM92378.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) Calreticulin PF00262.18 EIM92379.1 - 2.6e-158 526.7 6.2 3.9e-158 526.1 6.2 1.3 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.27 EIM92380.1 - 8.8e-46 155.9 0.0 1.3e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EIM92380.1 - 7.3e-37 126.7 4.6 1.2e-36 125.9 4.6 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EIM92380.1 - 1.1e-23 83.3 0.0 2.1e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EIM92380.1 - 4.7e-22 77.8 0.0 1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EIM92380.1 - 1e-11 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM92380.1 - 1.1e-06 28.7 0.2 2.1e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EIM92380.1 - 8.5e-06 25.8 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EIM92380.1 - 0.0019 17.6 0.1 0.006 16.0 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EIM92380.1 - 0.002 18.2 0.2 0.56 10.2 0.2 2.5 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 EIM92380.1 - 0.0085 15.7 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Ras family Prefoldin_2 PF01920.20 EIM92381.1 - 1.7e-15 56.9 6.6 2.1e-15 56.6 6.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 EIM92381.1 - 0.0054 16.9 0.5 0.0054 16.9 0.5 2.2 2 1 0 2 2 2 1 Tropomyosin like Mei5 PF10376.9 EIM92381.1 - 0.014 15.3 2.7 0.018 14.9 2.7 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein Coat_F PF07875.12 EIM92381.1 - 0.052 13.8 1.6 0.8 10.0 0.2 2.3 2 0 0 2 2 2 0 Coat F domain DUF5320 PF17253.2 EIM92381.1 - 0.07 14.2 0.7 0.16 13.1 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF148 PF02520.17 EIM92381.1 - 0.21 11.7 6.6 0.75 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 Prefoldin PF02996.17 EIM92381.1 - 3.4 7.6 9.2 1.3 9.0 0.8 2.8 2 1 1 3 3 3 0 Prefoldin subunit TPR_1 PF00515.28 EIM92382.1 - 1.5e-11 43.6 15.5 0.00059 19.6 0.7 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIM92382.1 - 1.2e-08 34.4 13.7 0.0002 21.2 0.9 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIM92382.1 - 7.9e-08 31.9 13.2 5.5e-07 29.2 1.8 5.1 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 EIM92382.1 - 1.1e-05 25.5 2.1 0.021 15.2 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIM92382.1 - 7.1e-05 22.7 9.2 0.13 12.6 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat MIT PF04212.18 EIM92382.1 - 0.0012 18.9 0.3 25 5.0 0.1 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 EIM92382.1 - 0.0047 17.6 1.8 0.32 11.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EIM92382.1 - 0.029 15.0 0.4 0.029 15.0 0.4 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIM92382.1 - 0.085 13.4 7.6 0.47 11.0 1.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIM92382.1 - 0.17 12.6 1.4 16 6.4 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIM92382.1 - 0.39 11.0 8.4 6.2 7.2 2.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat T3SSipB PF16535.5 EIM92382.1 - 1.3 9.5 8.8 1.2 9.7 0.6 2.8 2 1 1 3 3 3 0 Type III cell invasion protein SipB LPMO_10 PF03067.15 EIM92384.1 - 1e-05 26.3 0.1 1.6e-05 25.6 0.1 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ADH_zinc_N PF00107.26 EIM92386.1 - 2e-26 92.5 0.1 3.4e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIM92386.1 - 5.7e-16 59.8 0.0 1.5e-15 58.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIM92386.1 - 0.00031 20.6 0.0 0.0075 16.1 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.6 EIM92386.1 - 0.0033 17.4 0.2 0.014 15.4 0.2 2.0 2 0 0 2 2 2 1 SIS domain PALP PF00291.25 EIM92386.1 - 0.01 15.3 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 EIM92386.1 - 0.026 14.8 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PA PF02225.22 EIM92386.1 - 0.039 14.0 0.0 0.31 11.1 0.0 2.3 2 1 0 2 2 2 0 PA domain RabGAP-TBC PF00566.18 EIM92387.1 - 9.5e-49 166.0 0.0 1.3e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ING PF12998.7 EIM92389.1 - 1.4e-14 54.5 0.8 2.1e-14 53.9 0.8 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EIM92389.1 - 0.00021 21.1 8.7 0.00033 20.5 8.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EIM92389.1 - 0.02 15.2 1.8 0.038 14.2 1.8 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Fip1 PF05182.13 EIM92390.1 - 4.3e-19 67.8 2.3 6.9e-19 67.1 2.3 1.3 1 0 0 1 1 1 1 Fip1 motif Pox_Ag35 PF03286.14 EIM92390.1 - 1.9 8.2 5.0 3.8 7.2 5.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2431 PF10354.9 EIM92391.1 - 1.3e-50 172.0 0.0 1.8e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltr_RsmB-F PF01189.17 EIM92391.1 - 0.14 11.8 0.4 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PBP1_TM PF14812.6 EIM92391.1 - 0.4 11.1 4.7 0.26 11.7 1.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAF1C_H4-bd PF12265.8 EIM92392.1 - 4.9e-25 87.6 0.4 2e-24 85.6 0.4 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EIM92392.1 - 9.3e-18 64.3 12.8 0.00014 22.5 0.8 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92392.1 - 8.6e-06 26.0 0.9 0.036 14.4 0.1 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM92392.1 - 0.098 12.5 0.2 1 9.2 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A ATP-synt_E PF05680.12 EIM92393.1 - 3.5e-18 65.7 0.1 4.1e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain Caudo_TAP PF02413.17 EIM92393.1 - 0.002 18.3 0.1 0.0023 18.1 0.1 1.1 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK GFA PF04828.14 EIM92394.1 - 4.1e-09 36.7 3.1 8e-09 35.7 3.1 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme TFIIA PF03153.13 EIM92395.1 - 0.75 9.7 6.2 1.5 8.8 6.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dopey_N PF04118.14 EIM92396.1 - 3.6e-110 367.9 0.0 4.5e-109 364.3 0.0 2.4 2 0 0 2 2 2 1 Dopey, N-terminal HEAT_EZ PF13513.6 EIM92396.1 - 0.13 12.8 2.1 21 5.8 0.4 4.2 3 0 0 3 3 3 0 HEAT-like repeat EF-hand_7 PF13499.6 EIM92397.1 - 1.2e-08 35.2 0.9 3.1e-08 33.9 0.9 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EIM92397.1 - 7.9e-08 31.6 0.2 0.00026 20.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EIM92397.1 - 0.00014 21.1 0.9 0.029 13.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EIM92397.1 - 0.00029 20.2 0.2 0.69 9.5 0.1 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EIM92397.1 - 0.0038 17.5 2.9 0.9 9.9 0.3 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EIM92397.1 - 0.2 11.6 0.5 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair Y_phosphatase PF00102.27 EIM92398.1 - 5e-39 134.3 0.0 7e-38 130.5 0.0 2.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EIM92398.1 - 0.0042 17.2 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate FhuF PF06276.12 EIM92398.1 - 0.06 13.7 0.1 0.23 11.8 0.1 2.0 3 0 0 3 3 3 0 Ferric iron reductase FhuF-like transporter DSPc PF00782.20 EIM92398.1 - 0.068 13.0 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EIM92398.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Pkinase PF00069.25 EIM92399.1 - 1.4e-37 129.6 0.0 1.7e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92399.1 - 5.1e-19 68.6 0.0 6.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM92399.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EIM92399.1 - 0.0052 16.7 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIM92399.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EIM92399.1 - 0.085 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Grp7_allergen PF16984.5 EIM92399.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Group 7 allergen Kdo PF06293.14 EIM92399.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HNH_2 PF13391.6 EIM92400.1 - 0.0011 19.0 0.0 0.035 14.3 0.0 2.7 2 1 0 2 2 2 1 HNH endonuclease DUF1775 PF07987.11 EIM92400.1 - 0.04 14.2 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) Pkinase PF00069.25 EIM92401.1 - 3.2e-36 125.0 0.0 4.5e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92401.1 - 4.4e-23 81.9 0.0 5.8e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM92401.1 - 0.00078 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CSTF_C PF14304.6 EIM92403.1 - 3e-14 52.3 1.4 6.5e-14 51.2 1.4 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 EIM92403.1 - 2.3e-08 34.4 3.1 2.6e-08 34.2 1.5 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Adaptin_N PF01602.20 EIM92404.1 - 4.1e-90 302.8 3.5 5.8e-90 302.3 3.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EIM92404.1 - 1.6e-59 199.5 0.0 5.9e-59 197.6 0.0 2.1 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EIM92404.1 - 1.4e-53 180.6 0.0 3.6e-53 179.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 EIM92404.1 - 5.3e-11 42.8 0.1 0.016 15.6 0.0 4.9 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 EIM92404.1 - 1.3e-07 31.2 0.0 0.081 13.2 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EIM92404.1 - 3.7e-06 27.1 4.7 0.019 15.0 0.0 3.8 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 EIM92404.1 - 9e-05 22.6 0.0 0.0004 20.5 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform RTP1_C1 PF10363.9 EIM92404.1 - 0.0001 22.5 3.2 0.055 13.7 0.0 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF5578 PF17741.1 EIM92404.1 - 0.00043 19.8 4.3 0.51 9.7 0.9 3.6 1 1 2 3 3 3 2 Family of unknown function (DUF5578) Gemini_V2 PF01524.17 EIM92404.1 - 0.0015 18.6 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 Geminivirus V2 protein DUF5071 PF16804.5 EIM92404.1 - 0.0093 16.2 0.1 0.2 11.9 0.0 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF5071) Meis_PKNOX_N PF16493.5 EIM92404.1 - 0.026 14.9 0.4 0.17 12.2 0.4 2.4 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 ParcG PF10274.9 EIM92404.1 - 0.03 14.5 1.3 0.65 10.1 0.0 2.6 2 0 0 2 2 2 0 Parkin co-regulated protein RasGEF_N_2 PF14663.6 EIM92404.1 - 0.19 12.1 1.3 6.4 7.2 0.0 3.8 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ribosomal_60s PF00428.19 EIM92404.1 - 2.2 8.9 8.4 6.3 7.5 0.1 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein ABC2_membrane PF01061.24 EIM92405.1 - 9.7e-70 234.2 45.3 1.2e-35 122.9 15.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EIM92405.1 - 2.9e-33 115.3 0.0 7e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EIM92405.1 - 2.3e-19 69.1 5.0 3.8e-16 58.8 0.0 3.1 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EIM92405.1 - 3.4e-12 46.8 0.5 9.2e-12 45.4 0.5 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal cobW PF02492.19 EIM92405.1 - 1.4e-05 24.7 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EIM92405.1 - 1.5e-05 25.5 0.3 0.027 15.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EIM92405.1 - 3.1e-05 24.2 0.0 0.019 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIM92405.1 - 0.00014 22.1 0.0 0.45 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EIM92405.1 - 0.00025 21.5 0.1 0.056 13.8 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EIM92405.1 - 0.0013 19.0 0.1 0.51 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EIM92405.1 - 0.0013 18.4 0.4 0.15 11.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 EIM92405.1 - 0.0014 19.1 0.1 0.91 9.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIM92405.1 - 0.0021 17.9 0.3 0.83 9.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EIM92405.1 - 0.0052 16.7 0.1 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EIM92405.1 - 0.041 13.3 0.0 0.55 9.6 0.0 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIM92405.1 - 0.042 13.4 0.7 0.22 11.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIM92405.1 - 0.076 12.7 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EIM92405.1 - 0.12 12.1 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EIM92405.1 - 0.18 12.1 0.7 7.1 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EIM92405.1 - 1 9.0 6.4 4 7.1 0.2 2.9 4 0 0 4 4 4 0 AAA domain ABC2_membrane_3 PF12698.7 EIM92405.1 - 1.9 7.5 33.8 1.2 8.2 14.3 2.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Adaptin_N PF01602.20 EIM92407.1 - 3e-107 359.4 4.4 3.8e-107 359.0 4.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EIM92407.1 - 3e-12 46.9 2.0 1.6e-07 31.5 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIM92407.1 - 2.3e-07 31.1 5.8 0.033 14.6 0.0 5.1 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EIM92407.1 - 2.8e-06 27.1 6.2 10 6.7 0.1 6.8 7 0 0 7 7 6 1 HEAT repeat RTP1_C1 PF10363.9 EIM92407.1 - 2.4e-05 24.5 5.0 0.19 11.9 0.1 3.9 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EIM92407.1 - 7.9e-05 23.1 3.8 70 4.1 0.0 6.8 7 0 0 7 7 7 0 HEAT-like repeat V-ATPase_H_C PF11698.8 EIM92407.1 - 0.0028 17.8 1.0 3 8.0 0.0 3.9 3 1 0 3 3 3 1 V-ATPase subunit H Npa1 PF11707.8 EIM92407.1 - 0.017 14.5 0.4 0.049 13.0 0.4 1.8 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Arm PF00514.23 EIM92407.1 - 0.051 13.6 0.4 1.8 8.8 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Antirestrict PF03230.13 EIM92407.1 - 0.052 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Antirestriction protein FANCI_S1 PF14675.6 EIM92407.1 - 0.12 12.0 3.0 1.3 8.5 0.1 3.3 3 1 0 4 4 4 0 FANCI solenoid 1 Pkinase PF00069.25 EIM92408.1 - 2.8e-71 240.0 0.0 4e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92408.1 - 1.3e-51 175.4 0.0 2.3e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM92408.1 - 5e-05 22.3 0.0 8.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIM92408.1 - 0.00029 20.3 0.0 0.0042 16.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 EIM92408.1 - 0.0022 17.6 0.1 0.0044 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 EIM92408.1 - 0.0069 15.4 0.0 0.67 8.8 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain DUF5133 PF17196.4 EIM92408.1 - 0.16 12.2 0.2 0.42 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) Involucrin_N PF10583.9 EIM92408.1 - 0.19 12.3 0.9 0.49 11.0 0.9 1.6 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus UQ_con PF00179.26 EIM92409.1 - 7.1e-23 80.8 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EIM92409.1 - 3.1e-05 23.8 0.1 6.6e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 UEV domain Cation_efflux PF01545.21 EIM92410.1 - 8.7e-20 71.3 8.6 1.1e-19 71.0 8.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EIM92410.1 - 9.2e-12 44.9 0.2 1.8e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter EspB PF05802.11 EIM92411.1 - 0.06 13.3 8.6 0.15 12.1 8.6 1.7 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF996 PF06195.13 EIM92412.1 - 0.27 11.5 5.6 0.53 10.6 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF996) ABC_membrane PF00664.23 EIM92413.1 - 7.5e-74 248.8 23.9 4.6e-41 141.3 10.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM92413.1 - 1.4e-52 177.9 0.0 1e-29 103.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM92413.1 - 4.7e-07 29.5 3.1 0.0083 15.6 0.0 3.5 3 1 1 4 4 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EIM92413.1 - 7.4e-06 26.0 1.5 0.027 14.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EIM92413.1 - 0.00027 20.3 0.7 0.076 12.3 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 EIM92413.1 - 0.0003 21.2 0.1 0.38 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EIM92413.1 - 0.00093 19.1 1.4 1.4 8.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM92413.1 - 0.0011 18.7 0.0 0.061 13.0 0.0 2.7 3 1 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EIM92413.1 - 0.0014 18.5 1.7 0.61 10.0 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase TrwB_AAD_bind PF10412.9 EIM92413.1 - 0.0045 15.9 3.3 0.16 10.8 0.2 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 EIM92413.1 - 0.0046 16.7 5.3 0.33 10.7 0.3 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EIM92413.1 - 0.0077 16.0 0.6 4 7.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EIM92413.1 - 0.011 15.9 0.7 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EIM92413.1 - 0.012 15.6 1.1 0.22 11.5 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EIM92413.1 - 0.014 15.9 8.3 0.39 11.2 0.4 2.8 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EIM92413.1 - 0.014 14.9 0.6 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EIM92413.1 - 0.018 15.3 1.9 7.7 6.8 0.1 3.1 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EIM92413.1 - 0.044 13.4 1.6 0.22 11.1 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EIM92413.1 - 0.064 12.8 0.1 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIM92413.1 - 0.07 12.3 1.1 4 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 EIM92413.1 - 0.076 13.1 4.0 1.5 8.9 0.2 2.6 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 EIM92413.1 - 0.092 12.9 2.1 19 5.4 0.2 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EIM92413.1 - 0.11 12.6 4.7 0.17 12.0 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 EIM92413.1 - 0.17 11.5 0.0 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EIM92413.1 - 0.23 11.4 0.9 0.93 9.4 0.1 2.2 2 0 0 2 2 2 0 NACHT domain MobB PF03205.14 EIM92413.1 - 0.31 10.9 1.4 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Glutaredoxin PF00462.24 EIM92414.1 - 9.1e-18 64.2 0.0 1.2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EIM92414.1 - 6.4e-05 22.9 0.0 8.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 EIM92414.1 - 0.0012 19.3 0.1 0.0023 18.3 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EIM92414.1 - 0.003 17.9 0.1 0.004 17.5 0.1 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 EIM92414.1 - 0.014 15.4 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3179 PF11376.8 EIM92414.1 - 0.072 12.5 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) DSBA PF01323.20 EIM92414.1 - 0.1 12.3 0.2 0.69 9.7 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF1028 PF06267.12 EIM92414.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF1028) Complex1_49kDa PF00346.19 EIM92415.1 - 4.3e-121 403.2 0.0 5.5e-121 402.8 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EIM92415.1 - 0.0035 16.3 0.0 0.0055 15.7 0.0 1.5 1 0 0 1 1 1 1 Nickel-dependent hydrogenase CIMR PF00878.18 EIM92416.1 - 7.1e-12 45.6 0.0 1.7e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EIM92416.1 - 4.3e-10 39.1 0.0 5.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EIM92416.1 - 1.5e-08 34.8 0.0 2e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 TGF_beta_GS PF08515.12 EIM92416.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif GPI-anchored PF10342.9 EIM92417.1 - 5.5e-07 30.3 0.1 5.5e-07 30.3 0.1 2.7 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SPX PF03105.19 EIM92417.1 - 2.6 7.9 6.9 2.7 7.8 6.9 1.1 1 0 0 1 1 1 0 SPX domain Peptidase_M76 PF09768.9 EIM92418.1 - 2.2e-68 229.4 1.9 2.5e-68 229.2 1.9 1.0 1 0 0 1 1 1 1 Peptidase M76 family Melibiase_2_C PF17450.2 EIM92418.1 - 0.19 12.0 0.0 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain ECH_1 PF00378.20 EIM92419.1 - 3.3e-60 203.5 0.0 4.2e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIM92419.1 - 1.9e-30 106.5 0.1 4.1e-30 105.4 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Wzy_C_2 PF11846.8 EIM92419.1 - 0.0059 16.5 0.2 0.0094 15.9 0.2 1.2 1 0 0 1 1 1 1 Virulence factor membrane-bound polymerase, C-terminal T7SS_ESX_EspC PF10824.8 EIM92419.1 - 0.053 14.0 0.3 0.12 12.9 0.3 1.5 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm HrpB7 PF09486.10 EIM92419.1 - 0.092 13.1 0.5 0.15 12.4 0.5 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) TPX2 PF06886.11 EIM92421.1 - 8.5e-11 41.9 25.6 1.5e-10 41.2 22.3 2.6 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) UPF0564 PF10595.9 EIM92421.1 - 1.6e-06 27.5 7.7 1.6e-06 27.5 7.7 2.5 2 1 0 3 3 3 1 Uncharacterised protein family UPF0564 Porph_ging PF09697.10 EIM92421.1 - 0.097 13.2 2.9 0.4 11.3 2.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Fasciclin PF02469.22 EIM92422.1 - 1e-09 38.7 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Aldo_ket_red PF00248.21 EIM92423.1 - 1.4e-59 201.8 0.0 1.6e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIM92424.1 - 4.9e-58 196.6 0.0 2.2e-31 109.1 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Utp14 PF04615.13 EIM92426.1 - 3.3e-191 637.7 56.2 3.3e-191 637.7 56.2 2.3 1 1 0 2 2 2 1 Utp14 protein SNF2_N PF00176.23 EIM92427.1 - 5e-66 222.8 0.0 6.7e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM92427.1 - 1.4e-14 54.3 0.0 3.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EIM92427.1 - 7.6e-14 51.4 0.0 3.9e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 HIRAN domain ResIII PF04851.15 EIM92427.1 - 6.7e-07 29.5 0.0 5e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EIM92427.1 - 6.5e-05 22.7 14.2 0.00013 21.7 14.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM92427.1 - 0.00021 21.1 16.6 0.0034 17.2 16.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIM92427.1 - 0.00034 20.6 11.7 0.00076 19.5 10.9 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EIM92427.1 - 0.0068 16.2 11.9 0.013 15.4 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM92427.1 - 0.024 14.9 13.6 0.056 13.8 13.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EIM92427.1 - 0.06 13.3 12.9 0.12 12.3 12.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EIM92427.1 - 0.14 12.4 15.6 0.27 11.4 15.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Tim10_DDP PF02953.15 EIM92427.1 - 2 8.1 5.6 4.1 7.1 5.6 1.5 1 0 0 1 1 1 0 Tim10/DDP family zinc finger zf-MIZ PF02891.20 EIM92427.1 - 2.2 8.1 9.1 3.8 7.3 9.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.6 EIM92427.1 - 9.3 6.1 13.7 26 4.7 13.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cpn60_TCP1 PF00118.24 EIM92428.1 - 5.8e-150 500.1 0.7 6.7e-150 500.0 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.16 EIM92429.1 - 1.3e-21 76.9 22.8 1.3e-21 76.9 22.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily BSP PF04450.12 EIM92430.1 - 8.8e-64 215.1 0.0 1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 EIM92430.1 - 0.068 13.0 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 SprT-like family LSM PF01423.22 EIM92431.1 - 9.3e-19 66.9 0.3 1.3e-18 66.5 0.3 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EIM92431.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Dynein_attach_N PF15867.5 EIM92431.1 - 0.11 12.5 1.1 2.1 8.3 0.0 2.3 2 1 0 2 2 2 0 Dynein attachment factor N-terminus zf-CpG_bind_C PF12269.8 EIM92432.1 - 0.00072 19.4 1.9 0.0017 18.2 1.9 1.5 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain Ribosomal_60s PF00428.19 EIM92432.1 - 9.4 6.9 13.4 7.7 7.2 3.5 3.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein HABP4_PAI-RBP1 PF04774.15 EIM92433.1 - 1.8e-06 28.8 23.2 1.8e-06 28.8 23.2 3.6 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family Memo PF01875.17 EIM92434.1 - 1.6e-69 234.1 0.0 1.9e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein PAP2 PF01569.21 EIM92435.1 - 5.7e-12 45.6 10.0 5.7e-12 45.6 10.0 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EIM92435.1 - 0.00092 19.3 2.2 0.0094 16.1 0.0 2.7 1 1 2 3 3 3 1 Divergent PAP2 family ROS_MUCR PF05443.11 EIM92435.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Y_phosphatase PF00102.27 EIM92437.1 - 6.4e-50 169.9 0.0 2.4e-34 118.9 0.0 4.3 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 EIM92437.1 - 0.019 15.5 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain Y_phosphatase3 PF13350.6 EIM92437.1 - 0.023 14.7 0.0 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family NIF PF03031.18 EIM92439.1 - 1.7e-23 83.1 0.0 2.2e-20 73.0 0.0 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 EIM92439.1 - 6.3e-08 32.5 0.4 7.2e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EIM92439.1 - 3.5e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EIM92439.1 - 0.00024 21.3 0.1 0.00078 19.7 0.1 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain ETC_C1_NDUFA5 PF04716.14 EIM92440.1 - 2.1e-24 85.1 0.5 3.7e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_L32p PF01783.23 EIM92441.1 - 2.7e-18 66.0 3.4 3.3e-18 65.7 3.4 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 EIM92441.1 - 0.003 17.5 0.2 0.0035 17.3 0.2 1.2 1 0 0 1 1 1 1 zinc-ribbons TackOD1 PF18551.1 EIM92441.1 - 0.012 15.2 0.7 0.013 15.1 0.7 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 DZR PF12773.7 EIM92441.1 - 0.013 15.5 0.5 0.017 15.1 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 EIM92441.1 - 0.017 15.0 1.1 0.047 13.6 1.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 EIM92441.1 - 0.039 14.1 2.5 0.41 10.8 0.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain DUF1272 PF06906.11 EIM92441.1 - 0.064 13.3 1.9 0.097 12.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_Tnp_IS1595 PF12760.7 EIM92441.1 - 0.27 11.2 4.6 6.1 6.9 4.6 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.16 EIM92441.1 - 0.36 10.9 4.6 1 9.5 1.3 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1610 PF07754.11 EIM92441.1 - 0.45 10.5 0.6 0.45 10.5 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.6 EIM92441.1 - 1.8 8.0 9.2 31 4.1 9.2 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Thiolase_N PF00108.23 EIM92442.1 - 1.6e-66 224.4 0.0 2.3e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIM92442.1 - 1.4e-37 128.0 0.3 4.2e-37 126.5 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EIM92442.1 - 0.0019 17.8 0.7 0.0066 16.1 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EIM92442.1 - 0.0065 16.3 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Amidase PF01425.21 EIM92443.1 - 5.3e-108 361.9 0.0 6.5e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF896 PF05979.12 EIM92443.1 - 0.15 11.9 0.2 0.31 11.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Ribosomal_S3_C PF00189.20 EIM92445.1 - 6.2e-25 87.5 0.1 2.2e-24 85.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EIM92445.1 - 5.3e-12 45.4 0.0 9.7e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EIM92445.1 - 0.058 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EIM92445.1 - 0.21 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus Lyase_8 PF02278.18 EIM92446.1 - 7.2e-71 238.7 5.1 1.2e-70 237.9 5.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 EIM92446.1 - 1.4e-19 70.2 0.2 3.1e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 EIM92446.1 - 1.4e-08 35.0 0.4 3.2e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain CbtB PF09489.10 EIM92447.1 - 0.67 10.1 5.1 4.5 7.5 0.6 2.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Mpp10 PF04006.12 EIM92448.1 - 1.8e-116 390.1 60.5 1e-115 387.6 60.4 1.8 1 1 0 1 1 1 1 Mpp10 protein V-SNARE_C PF12352.8 EIM92449.1 - 0.00056 20.1 4.6 0.3 11.4 0.2 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus ATG16 PF08614.11 EIM92450.1 - 0.0002 21.7 3.8 0.0002 21.7 3.8 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EIM92450.1 - 0.0056 16.7 1.9 0.011 15.7 1.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EIM92450.1 - 0.0061 16.6 4.3 0.0081 16.2 3.2 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.12 EIM92450.1 - 0.0096 16.0 1.2 0.97 9.6 0.2 2.5 1 1 1 2 2 2 1 MbeD/MobD like FlaC_arch PF05377.11 EIM92450.1 - 0.0097 16.3 1.3 0.018 15.4 1.3 1.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 EIM92450.1 - 0.012 15.8 0.8 0.023 14.9 0.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-CCCH_3 PF15663.5 EIM92450.1 - 0.066 13.4 1.1 0.14 12.4 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger containing family DUF4047 PF13256.6 EIM92450.1 - 0.098 12.8 1.8 0.15 12.3 0.5 1.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4047) GAS PF13851.6 EIM92450.1 - 0.1 12.0 3.2 0.16 11.3 3.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 EIM92450.1 - 0.11 13.0 1.5 0.18 12.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Torus PF16131.5 EIM92450.1 - 0.12 13.1 0.5 0.26 12.0 0.1 1.9 2 0 0 2 2 1 0 Torus domain ERM PF00769.19 EIM92450.1 - 0.13 12.1 2.5 0.2 11.4 2.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family BRE1 PF08647.11 EIM92450.1 - 0.14 12.3 3.8 0.26 11.4 3.8 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase KxDL PF10241.9 EIM92450.1 - 0.18 12.1 0.9 0.31 11.3 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein Swi5 PF07061.11 EIM92450.1 - 0.19 11.8 0.3 0.45 10.6 0.3 1.6 1 0 0 1 1 1 0 Swi5 Laminin_II PF06009.12 EIM92450.1 - 0.21 11.6 3.1 0.31 11.0 3.1 1.2 1 0 0 1 1 1 0 Laminin Domain II JIP_LZII PF16471.5 EIM92450.1 - 0.22 11.7 2.8 1.5 9.0 2.7 2.2 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II LPP PF04728.13 EIM92450.1 - 0.36 11.2 1.4 3.6 8.0 0.2 2.3 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 EIM92450.1 - 0.38 10.9 6.0 0.69 10.1 6.0 1.3 1 0 0 1 1 1 0 Tropomyosin like BMFP PF04380.13 EIM92450.1 - 0.4 11.2 3.8 0.26 11.8 0.8 2.0 2 0 0 2 2 2 0 Membrane fusogenic activity DUF724 PF05266.14 EIM92450.1 - 0.46 10.3 3.7 1.1 9.0 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CLZ PF16526.5 EIM92450.1 - 0.5 10.8 2.7 13 6.2 2.3 2.5 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SAD_SRA PF02182.17 EIM92451.1 - 3.1e-49 166.7 0.0 5.9e-49 165.8 0.0 1.5 2 0 0 2 2 2 1 SAD/SRA domain PEX-2N PF09263.10 EIM92452.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal DUF1180 PF06679.12 EIM92453.1 - 0.017 15.5 7.7 0.021 15.2 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Apt1 PF10351.9 EIM92453.1 - 6.3 5.5 6.2 6.6 5.5 6.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 EIM92454.1 - 0.13 11.9 10.4 0.15 11.7 10.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 UPF0160 PF03690.13 EIM92455.1 - 1.2e-139 465.4 0.0 1.4e-139 465.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Zn_clus PF00172.18 EIM92456.1 - 7.4e-07 29.2 7.7 1e-06 28.7 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SurE PF01975.17 EIM92457.1 - 1.1e-47 162.4 0.0 1.3e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_16 PF00722.21 EIM92458.1 - 2.1e-07 30.6 0.3 4.3e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ribosomal_L15e PF00827.17 EIM92459.1 - 2.6e-90 301.3 9.8 3e-90 301.1 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 RasGEF PF00617.19 EIM92460.1 - 1.2e-33 116.8 0.1 2.1e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EIM92460.1 - 3.8e-10 39.9 0.1 1.3e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 EIM92460.1 - 2.8e-06 27.0 0.0 5.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Ras family MARVEL PF01284.23 EIM92461.1 - 0.00055 20.0 13.3 0.0007 19.6 12.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain CcmD PF04995.14 EIM92461.1 - 0.0068 16.5 0.4 0.0068 16.5 0.4 2.6 3 0 0 3 3 3 1 Heme exporter protein D (CcmD) Methyltransf_23 PF13489.6 EIM92462.1 - 1.6e-08 34.6 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIM92462.1 - 0.018 15.6 0.0 0.045 14.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIM92462.1 - 0.036 14.8 0.0 0.069 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EIM92462.1 - 0.14 11.9 0.0 1.8 8.4 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Peroxidase_2 PF01328.17 EIM92463.1 - 2.1e-40 139.3 0.0 3.5e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 DpnII PF04556.12 EIM92463.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 DpnII restriction endonuclease Hexapep PF00132.24 EIM92464.1 - 9.5e-11 41.0 19.6 9.2e-07 28.4 2.1 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EIM92464.1 - 3.2e-06 26.8 10.8 0.001 18.8 0.6 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EIM92464.1 - 0.00028 20.0 0.0 0.00039 19.5 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase DEAD PF00270.29 EIM92465.1 - 3.3e-48 163.8 0.0 7.3e-48 162.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM92465.1 - 1.7e-29 102.4 0.0 1.9e-27 95.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM92465.1 - 6.6e-05 23.0 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 EIM92465.1 - 0.21 10.9 50.1 0.028 13.8 29.0 2.2 2 0 0 2 2 2 0 BUD22 Lipase_3 PF01764.25 EIM92466.1 - 3.1e-23 82.2 0.0 4.9e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EIM92466.1 - 0.00061 20.5 0.2 0.0012 19.5 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM92466.1 - 0.0056 16.3 0.1 0.17 11.5 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF3918 PF13056.6 EIM92466.1 - 1.2 8.8 3.0 0.86 9.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) MFS_1 PF07690.16 EIM92467.1 - 4.2e-24 85.1 37.4 1e-17 64.1 27.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SARAF PF06682.12 EIM92467.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Glyco_hydro_71 PF03659.14 EIM92468.1 - 4.7e-106 354.8 4.2 5.8e-106 354.5 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 ANAPC4 PF12896.7 EIM92469.1 - 2.4e-44 151.3 0.0 4.4e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EIM92469.1 - 0.00013 22.2 0.1 0.00099 19.4 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 EIM92470.1 - 7.3e-05 22.8 3.3 7.3e-05 22.8 3.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor ddrB-ParB PF18763.1 EIM92470.1 - 0.018 15.2 0.2 0.054 13.6 0.2 2.0 1 1 0 1 1 1 0 ddrB-like ParB superfamily domain GIT_CC PF16559.5 EIM92470.1 - 0.072 13.0 0.6 0.13 12.2 0.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 EIM92470.1 - 0.096 13.3 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 SlyX TolA_bind_tri PF16331.5 EIM92470.1 - 0.1 12.7 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation ZapB PF06005.12 EIM92470.1 - 0.26 11.8 1.6 0.46 11.0 1.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 EIM92470.1 - 0.39 10.8 10.0 0.06 13.4 1.8 2.7 2 1 1 3 3 3 0 Basic region leucine zipper GPI2 PF06432.11 EIM92471.1 - 1.1e-87 294.0 13.5 1.3e-87 293.9 13.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SVIP PF15811.5 EIM92472.1 - 0.26 11.8 8.9 0.28 11.7 7.5 1.9 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Actin PF00022.19 EIM92474.1 - 3.1e-129 431.2 0.0 1.4e-128 429.0 0.0 1.7 1 1 0 1 1 1 1 Actin Ribosomal_S24e PF01282.19 EIM92475.1 - 2.6e-33 113.8 0.0 4.3e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e HEAT PF02985.22 EIM92478.1 - 2.9e-46 151.5 15.5 0.0015 18.6 0.0 13.8 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 EIM92478.1 - 9e-40 135.0 9.7 2.8e-11 43.7 0.0 7.4 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 EIM92478.1 - 1.7e-14 53.9 6.0 0.0045 17.5 0.1 9.1 8 2 2 10 10 10 2 HEAT-like repeat Cnd1 PF12717.7 EIM92478.1 - 1.7e-12 47.7 0.9 0.00078 19.5 0.0 5.2 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EIM92478.1 - 2.9e-12 47.0 0.6 0.0085 16.7 0.0 6.8 4 2 3 7 7 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EIM92478.1 - 1.4e-07 30.5 3.9 1.5e-05 23.8 0.6 3.5 3 2 0 3 3 3 2 Adaptin N terminal region Arm PF00514.23 EIM92478.1 - 0.00032 20.6 5.6 5 7.3 0.0 6.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EIM92478.1 - 0.056 14.1 4.2 1.6 9.6 0.5 5.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat EnY2 PF10163.9 EIM92478.1 - 0.08 13.3 0.1 0.9 10.0 0.1 2.9 3 0 0 3 3 3 0 Transcription factor e(y)2 Ecm29 PF13001.7 EIM92478.1 - 0.1 11.3 4.4 10 4.7 0.0 4.2 4 2 0 4 4 4 0 Proteasome stabiliser CIA30 PF08547.12 EIM92479.1 - 1.9e-37 128.7 0.0 2.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) HMG_box PF00505.19 EIM92480.1 - 5.8e-13 49.1 2.0 7.4e-13 48.7 0.6 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIM92480.1 - 0.00022 21.8 0.1 0.00055 20.5 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain PolyA_pol PF01743.20 EIM92481.1 - 1.1e-22 80.8 0.1 2e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EIM92481.1 - 0.22 11.3 0.3 0.7 9.7 0.1 1.9 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Abhydrolase_2 PF02230.16 EIM92482.1 - 6.2e-27 94.8 0.0 7.4e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EIM92482.1 - 6.5e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EIM92482.1 - 0.0002 21.0 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EIM92482.1 - 0.0026 18.4 0.1 0.0029 18.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EIM92482.1 - 0.0096 15.8 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EIM92482.1 - 0.086 12.5 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Arm PF00514.23 EIM92483.1 - 2.6e-72 236.9 29.5 4.9e-13 48.6 0.1 11.4 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EIM92483.1 - 7.4e-20 71.1 12.1 0.00091 19.7 0.3 7.9 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 EIM92483.1 - 1.6e-17 63.7 6.7 0.0096 16.3 0.0 7.0 4 3 2 6 6 6 5 HEAT repeats HEAT PF02985.22 EIM92483.1 - 4.1e-16 57.7 12.0 0.19 12.1 0.0 9.7 9 0 0 9 9 9 5 HEAT repeat Arm_2 PF04826.13 EIM92483.1 - 8.7e-13 48.3 9.9 1.1e-08 34.9 1.8 2.5 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 EIM92483.1 - 2.7e-11 42.7 12.1 1.6e-09 36.9 1.4 3.0 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.12 EIM92483.1 - 4.7e-09 35.0 2.5 6.3e-09 34.5 2.5 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EIM92483.1 - 1.9e-07 30.7 10.0 0.00077 18.8 1.2 4.1 1 1 2 4 4 4 3 V-ATPase subunit H Cnd1 PF12717.7 EIM92483.1 - 8.4e-07 29.2 9.3 0.031 14.3 0.1 5.1 1 1 4 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EIM92483.1 - 0.00093 19.2 6.3 1.1 9.2 0.0 4.0 1 1 3 4 4 4 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EIM92483.1 - 0.0034 17.5 3.5 25 5.0 0.0 5.0 1 1 5 6 6 6 0 V-ATPase subunit H HEAT_PBS PF03130.16 EIM92483.1 - 0.0037 17.8 10.5 6.5 7.7 0.4 7.1 7 0 0 7 7 7 1 PBS lyase HEAT-like repeat DUF5578 PF17741.1 EIM92483.1 - 0.0076 15.7 8.6 3 7.2 0.1 4.2 2 1 2 4 4 4 2 Family of unknown function (DUF5578) Vac14_Fab1_bd PF12755.7 EIM92483.1 - 0.02 15.5 0.2 10 6.8 0.0 3.5 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 EIM92483.1 - 0.3 11.1 3.4 1.1 9.3 0.1 3.4 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 EIM92483.1 - 5.8 7.4 5.6 30 5.1 0.2 3.8 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ribosomal_L33 PF00471.20 EIM92484.1 - 2.6e-08 34.2 0.0 3.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 EIM92484.1 - 0.073 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Amidohydro_3 PF07969.11 EIM92485.1 - 6.2e-74 250.2 0.0 7.5e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EIM92485.1 - 2.4e-12 46.8 0.0 2.3e-09 37.0 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family GYF PF02213.16 EIM92486.1 - 4.3e-15 55.1 1.2 1e-14 53.9 1.2 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EIM92486.1 - 0.033 14.0 0.2 0.083 12.7 0.2 1.8 1 0 0 1 1 1 0 GYF domain 2 Acatn PF13000.7 EIM92487.1 - 2e-151 505.2 26.5 3.3e-70 237.1 17.9 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Glyco_hydro_127 PF07944.12 EIM92488.1 - 1e-24 87.0 0.1 2e-23 82.7 0.0 2.0 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 HTH_Tnp_Tc5 PF03221.16 EIM92488.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Pkinase_Tyr PF07714.17 EIM92489.1 - 7.2e-29 100.8 0.0 9.6e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIM92489.1 - 1.1e-28 100.3 0.0 1.5e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIM92489.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EIM92489.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EIM92489.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_72 PF03198.14 EIM92490.1 - 2.3e-92 309.6 0.6 3e-92 309.2 0.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EIM92490.1 - 3.5e-21 75.7 3.0 7e-21 74.7 2.3 2.0 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 EIM92490.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 EIM92491.1 - 2.5e-14 52.9 0.1 3.3e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EIM92491.1 - 9.6e-09 34.9 2.7 1.6e-08 34.3 2.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EIM92491.1 - 0.00026 20.9 0.2 0.00047 20.1 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIM92491.1 - 0.0029 17.3 1.8 0.0029 17.3 1.8 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EIM92491.1 - 0.023 14.5 1.4 0.05 13.4 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle RRM_7 PF16367.5 EIM92491.1 - 0.19 11.8 0.0 0.43 10.7 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif zf-CCHC_4 PF14392.6 EIM92491.1 - 0.25 11.1 0.2 0.39 10.5 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle ABC_membrane PF00664.23 EIM92492.1 - 1.7e-50 172.2 25.7 5.5e-25 88.5 8.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIM92492.1 - 2.6e-41 141.3 0.1 8.6e-24 84.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIM92492.1 - 4.2e-07 29.6 1.6 0.18 11.2 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIM92492.1 - 3.3e-06 26.8 0.0 0.039 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EIM92492.1 - 8.6e-06 26.4 0.3 0.00042 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIM92492.1 - 1.7e-05 24.8 4.8 0.0084 16.0 0.4 3.9 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIM92492.1 - 1.9e-05 24.3 0.3 0.039 13.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EIM92492.1 - 0.00011 22.6 0.1 0.64 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 EIM92492.1 - 0.00084 18.9 0.1 0.34 10.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 EIM92492.1 - 0.0013 17.8 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EIM92492.1 - 0.0014 18.7 0.6 1.1 9.4 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM92492.1 - 0.0016 18.3 0.2 0.55 10.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 EIM92492.1 - 0.011 15.9 3.5 0.16 12.1 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EIM92492.1 - 0.012 15.9 0.2 2.2 8.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EIM92492.1 - 0.014 14.7 0.2 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 EIM92492.1 - 0.016 15.2 0.7 9.6 6.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 EIM92492.1 - 0.02 14.9 1.4 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 EIM92492.1 - 0.028 14.2 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Adeno_IVa2 PF02456.15 EIM92492.1 - 0.04 12.7 0.5 0.4 9.4 0.0 2.3 3 0 0 3 3 3 0 Adenovirus IVa2 protein Roc PF08477.13 EIM92492.1 - 0.052 13.8 0.3 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 EIM92492.1 - 0.059 12.8 1.6 8.2 5.8 0.2 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_15 PF13175.6 EIM92492.1 - 0.07 12.8 0.1 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EIM92492.1 - 0.072 13.6 0.0 29 5.2 0.0 3.6 4 0 0 4 4 3 0 AAA domain DEAD PF00270.29 EIM92492.1 - 0.13 12.0 0.0 19 5.0 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase ResIII PF04851.15 EIM92492.1 - 0.14 12.2 0.0 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 EIM92492.1 - 0.25 11.1 0.7 7.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EIM92492.1 - 0.99 9.0 3.3 1.9 8.0 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RhoGAP PF00620.27 EIM92493.1 - 3e-37 127.8 0.0 6.2e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EIM92493.1 - 1.4e-07 31.7 1.8 2e-06 28.0 0.4 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain NleF_casp_inhib PF16809.5 EIM92493.1 - 0.048 13.6 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 NleF caspase inhibitor TEX12 PF15219.6 EIM92493.1 - 0.2 12.0 0.8 0.47 10.8 0.3 1.8 2 0 0 2 2 2 0 Testis-expressed 12 FAM184 PF15665.5 EIM92493.1 - 5.7 6.7 7.7 0.43 10.3 0.4 2.6 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B DUF4244 PF14029.6 EIM92494.1 - 0.022 14.2 0.6 0.022 14.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) DUF4501 PF14946.6 EIM92494.1 - 0.081 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DNA_pol_A_exo1 PF01612.20 EIM92495.1 - 3e-11 43.4 0.0 3.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease SprB PF13573.6 EIM92496.1 - 0.02 14.7 0.1 0.02 14.7 0.1 3.1 3 0 0 3 3 3 0 SprB repeat 5TM-5TMR_LYT PF07694.12 EIM92496.1 - 0.029 13.9 0.2 0.042 13.3 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Las1 PF04031.13 EIM92497.1 - 2.4e-43 147.9 0.2 5e-43 146.9 0.2 1.5 1 0 0 1 1 1 1 Las1-like LppA PF16708.5 EIM92497.1 - 0.15 11.9 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium DUF3433 PF11915.8 EIM92497.1 - 0.26 11.8 3.0 1.6 9.2 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) DLH PF01738.18 EIM92498.1 - 2e-11 43.9 0.0 2.6e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family FR47 PF08445.10 EIM92499.1 - 3.7e-05 23.6 0.0 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 EIM92499.1 - 0.00091 19.6 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIM92499.1 - 0.037 14.3 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EIM92499.1 - 0.049 14.3 0.0 0.18 12.5 0.0 1.9 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIM92499.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fe-S_biosyn PF01521.20 EIM92500.1 - 8.9e-21 74.2 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis F-box-like PF12937.7 EIM92501.1 - 1.3e-05 25.0 2.0 1.8e-05 24.5 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIM92501.1 - 0.0008 19.2 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain Prenylcys_lyase PF07156.14 EIM92502.1 - 4.7e-68 229.9 0.0 6.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EIM92502.1 - 5.4e-11 42.6 0.0 1.4e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIM92502.1 - 1.8e-10 40.7 0.0 8.8e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EIM92502.1 - 8.2e-08 32.2 0.1 0.0057 16.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIM92502.1 - 0.0024 17.9 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EIM92502.1 - 0.0055 16.0 0.0 0.044 13.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIM92502.1 - 0.016 14.0 0.6 1.4 7.5 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 EIM92502.1 - 0.045 13.0 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EIM92502.1 - 0.11 11.1 0.2 1 7.8 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 EIM92502.1 - 0.13 11.5 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EIM92502.1 - 0.24 10.4 0.8 0.5 9.4 0.8 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Ammonium_transp PF00909.21 EIM92503.1 - 2.5e-113 378.8 22.1 3e-113 378.5 22.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family adh_short PF00106.25 EIM92504.1 - 8.8e-29 100.3 0.1 4.6e-28 98.0 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM92504.1 - 2e-22 79.9 0.0 1.6e-20 73.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EIM92504.1 - 0.0044 16.5 0.1 0.0056 16.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIM92504.1 - 0.0068 16.3 0.0 0.3 11.0 0.0 2.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM92504.1 - 0.067 12.5 0.1 0.3 10.4 0.1 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) UMP1 PF05348.11 EIM92505.1 - 6.6e-34 116.7 0.4 7.7e-34 116.4 0.4 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.28 EIM92506.1 - 8.2e-21 74.3 0.4 1.4e-20 73.6 0.4 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 EIM92506.1 - 4.2e-17 62.4 0.0 6.2e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EIM92506.1 - 0.0012 18.7 1.2 0.0018 18.2 0.2 1.9 2 0 0 2 2 2 1 LisH NAD_binding_6 PF08030.12 EIM92507.1 - 1.4e-23 83.7 0.0 2.5e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIM92507.1 - 4.2e-21 75.1 0.0 1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EIM92507.1 - 2e-18 66.7 13.4 2e-18 66.7 13.4 2.0 1 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EIM92507.1 - 0.0026 18.4 0.0 0.069 13.8 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 EIM92507.1 - 0.027 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform HORMA PF02301.18 EIM92508.1 - 5.3e-16 58.9 0.0 7.3e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EIM92508.1 - 0.0062 16.5 0.3 0.072 13.1 0.3 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 Ribonuclease_3 PF00636.26 EIM92509.1 - 3.4e-08 34.1 0.0 1.2e-07 32.3 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIM92509.1 - 1.1e-06 28.9 0.0 8e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease-III-like IlvN PF07991.12 EIM92510.1 - 3.8e-49 166.4 0.1 5.7e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EIM92510.1 - 1.4e-21 77.3 0.2 1.9e-21 76.8 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EIM92510.1 - 1.4e-10 41.6 0.3 3.6e-10 40.3 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EIM92510.1 - 5.9e-06 26.5 0.0 9.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EIM92510.1 - 0.00016 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EIM92510.1 - 0.0028 17.6 0.2 0.019 14.9 0.2 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 EIM92510.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EIM92510.1 - 0.14 12.6 0.0 1.5 9.3 0.0 2.1 1 1 1 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 EIM92510.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short_C2 PF13561.6 EIM92511.1 - 2.4e-60 204.0 0.0 3e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM92511.1 - 2.1e-43 148.0 0.0 2.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM92511.1 - 7.1e-13 48.8 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.11 EIM92512.1 - 7.7e-07 28.7 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Pex16 PF08610.10 EIM92513.1 - 2.3e-114 381.9 1.2 2.6e-114 381.7 1.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF1489 PF07370.11 EIM92514.1 - 0.096 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) BTB PF00651.31 EIM92515.1 - 8.6e-05 22.7 0.1 0.0035 17.6 0.0 2.9 3 0 0 3 3 3 1 BTB/POZ domain FAD_binding_7 PF03441.14 EIM92518.1 - 2e-75 252.7 5.2 2.8e-75 252.2 2.0 2.4 2 1 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EIM92518.1 - 1.7e-34 119.2 0.1 3e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase CorA PF01544.18 EIM92519.1 - 3.8e-29 101.9 0.3 9.4e-14 51.4 0.1 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein TPD52 PF04201.15 EIM92519.1 - 0.054 13.1 0.1 11 5.6 0.1 2.6 1 1 1 2 2 2 0 Tumour protein D52 family RRP36 PF06102.12 EIM92520.1 - 1.4e-43 148.7 20.3 1.4e-43 148.7 20.3 1.6 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF2235 PF09994.9 EIM92522.1 - 1.6e-69 234.4 0.1 3.3e-69 233.4 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3923 PF13061.6 EIM92523.1 - 0.24 11.5 0.8 0.39 10.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) SNAP PF14938.6 EIM92524.1 - 2.7e-108 361.7 14.8 3.1e-108 361.5 14.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF410 PF04190.13 EIM92524.1 - 0.00061 19.7 1.7 0.019 14.8 1.7 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF410) Spatacsin_C PF14649.6 EIM92524.1 - 0.0012 18.0 2.2 0.047 12.8 0.2 2.2 1 1 0 2 2 2 2 Spatacsin C-terminus TPR_7 PF13176.6 EIM92524.1 - 0.0021 18.0 9.0 0.48 10.6 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat CAP PF00188.26 EIM92524.1 - 0.022 15.6 1.6 0.022 15.6 1.6 1.6 1 1 0 1 1 1 0 Cysteine-rich secretory protein family TPR_6 PF13174.6 EIM92524.1 - 0.052 14.2 5.1 3.7 8.4 0.1 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIM92524.1 - 0.32 10.7 6.4 4 7.2 0.1 4.4 4 0 0 4 4 4 0 TPR repeat NSF PF02071.20 EIM92524.1 - 1.7 9.7 9.1 7.9 7.8 0.0 5.6 5 1 1 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat PGM_PMM_I PF02878.16 EIM92525.1 - 3.7e-17 62.3 0.5 1e-07 31.7 0.1 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EIM92525.1 - 1.2e-11 44.6 0.3 2.1e-10 40.7 0.1 2.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EIM92525.1 - 0.0083 16.3 0.3 0.034 14.3 0.3 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EIM92525.1 - 0.086 13.5 0.2 2 9.1 0.2 3.0 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SOG2 PF10428.9 EIM92527.1 - 0.42 9.7 17.5 0.57 9.3 17.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GATase_4 PF13230.6 EIM92528.1 - 2.8e-20 72.3 0.0 8.7e-20 70.7 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EIM92528.1 - 1.5e-09 38.1 0.0 2.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain TENA_THI-4 PF03070.16 EIM92528.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family ICE2 PF08426.10 EIM92529.1 - 6.6e-34 117.7 27.6 1.4e-19 70.5 15.0 3.0 1 1 1 2 2 2 2 ICE2 BRCT_2 PF16589.5 EIM92530.1 - 2.9e-19 69.3 0.0 2.2e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIM92530.1 - 0.00069 19.9 0.0 0.025 15.0 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AT_hook PF02178.19 EIM92530.1 - 0.085 12.8 2.4 0.52 10.4 2.4 2.5 1 0 0 1 1 1 0 AT hook motif Sigma70_ner PF04546.13 EIM92530.1 - 0.18 11.7 9.4 0.43 10.4 9.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region RAP1 PF07218.11 EIM92530.1 - 0.21 9.8 1.6 0.45 8.7 1.6 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SDA1 PF05285.12 EIM92530.1 - 0.76 9.1 18.0 1.5 8.2 18.0 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIM92530.1 - 1.8 6.6 17.7 2.7 6.1 17.7 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EIM92530.1 - 5.2 5.0 22.2 7.8 4.5 22.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tim17 PF02466.19 EIM92531.1 - 3.1e-08 34.0 8.5 5.2e-08 33.3 8.5 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.12 EIM92531.1 - 0.8 9.2 6.7 1.5 8.3 6.7 1.5 1 1 0 1 1 1 0 5TMR of 5TMR-LYT SLATT_fungal PF18142.1 EIM92531.1 - 8.5 6.4 7.8 1 9.4 1.1 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Cornifin PF02389.15 EIM92532.1 - 0.00043 20.5 5.6 0.043 14.0 1.0 2.5 1 1 1 2 2 2 2 Cornifin (SPRR) family DUF3409 PF11889.8 EIM92532.1 - 0.0011 18.8 9.6 1.5e+02 2.4 0.0 7.6 8 0 0 8 8 8 0 Domain of unknown function (DUF3409) SspK PF08176.12 EIM92532.1 - 0.0067 16.7 7.9 3.5e+02 1.6 0.1 8.0 6 2 2 8 8 8 0 Small acid-soluble spore protein K family MAP1B_neuraxin PF00414.17 EIM92532.1 - 0.84 9.3 13.5 2.9e+02 1.2 0.0 7.3 8 0 0 8 8 8 0 Neuraxin and MAP1B repeat NUC153 PF08159.12 EIM92533.1 - 5.1e-16 58.2 22.3 9.9e-15 54.1 2.1 4.2 4 0 0 4 4 4 3 NUC153 domain CS PF04969.16 EIM92534.1 - 1.1e-18 68.0 0.9 1.5e-18 67.6 0.3 1.6 2 0 0 2 2 2 1 CS domain PINIT PF14324.6 EIM92535.1 - 2.4e-39 135.0 1.6 4.4e-39 134.1 1.6 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EIM92535.1 - 5.3e-19 67.7 8.0 1.1e-18 66.7 8.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EIM92535.1 - 0.00047 19.9 1.7 0.0013 18.5 1.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EIM92535.1 - 0.015 15.0 1.9 0.017 14.9 0.2 2.0 2 0 0 2 2 2 0 SAP domain PHD_4 PF16866.5 EIM92535.1 - 0.23 11.6 2.6 0.56 10.3 2.6 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EIM92535.1 - 0.31 10.9 3.9 0.89 9.5 3.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EIM92535.1 - 3.2 7.7 5.7 8 6.4 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIM92535.1 - 3.8 7.9 6.1 8.8 6.8 6.1 1.6 1 0 0 1 1 1 0 Ring finger domain Mito_carr PF00153.27 EIM92536.1 - 3.4e-65 216.0 6.2 5.5e-24 83.9 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ResIII PF04851.15 EIM92537.1 - 2e-19 70.3 0.0 4.8e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIM92537.1 - 7.5e-14 52.0 0.0 2.5e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM92537.1 - 3.2e-13 49.8 0.0 6.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EIM92537.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 EIM92537.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 EIM92537.1 - 0.0017 17.2 0.0 0.0037 16.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EIM92537.1 - 0.033 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 EIM92537.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Indigoidine_A PF04227.12 EIM92538.1 - 6.9e-110 367.0 0.0 8.3e-110 366.7 0.0 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein Asp23 PF03780.13 EIM92538.1 - 0.13 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function MoaE PF02391.17 EIM92539.1 - 1.1e-38 132.0 0.1 1.3e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 MoaE protein Ribosomal_L4 PF00573.22 EIM92540.1 - 1.1e-62 211.1 0.2 1.3e-62 210.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 EIM92541.1 - 3.2e-30 105.2 0.7 3.6e-30 105.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MG1 PF17790.1 EIM92541.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Macroglobulin domain MG1 Esterase PF00756.20 EIM92542.1 - 2.4e-36 125.7 0.0 6.1e-25 88.3 0.0 2.0 1 1 1 2 2 2 2 Putative esterase Chlorophyllase2 PF12740.7 EIM92542.1 - 0.022 13.7 0.0 0.065 12.1 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EIM92542.1 - 0.082 13.5 0.1 0.096 13.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM92542.1 - 0.14 11.4 0.0 0.36 10.0 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Con-6 PF10346.9 EIM92543.1 - 9.2e-37 124.8 7.2 4.1e-18 65.1 1.9 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Glyco_transf_8C PF08437.10 EIM92543.1 - 0.011 15.8 0.7 2.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal Zn_ribbon_recom PF13408.6 EIM92545.1 - 0.45 11.1 8.6 6.8 7.3 2.1 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.12 EIM92545.1 - 6.4 6.8 9.6 1.4e+02 2.6 9.6 2.5 1 1 0 1 1 1 0 zinc-ribbons Pkinase PF00069.25 EIM92547.1 - 2.6e-42 145.0 0.0 3.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92547.1 - 1.1e-22 80.6 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EIM92547.1 - 0.0028 18.0 0.2 0.0091 16.3 0.0 1.9 2 0 0 2 2 2 1 FHA domain ORC2 PF04084.14 EIM92547.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 2 MMR_HSR1 PF01926.23 EIM92548.1 - 4.8e-16 58.9 0.0 5.2e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM92548.1 - 7.4e-07 29.2 0.1 0.00069 19.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EIM92548.1 - 8.2e-06 25.4 0.1 4.3e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EIM92548.1 - 0.0004 19.8 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RNA_pol_3_Rpc31 PF11705.8 EIM92548.1 - 0.76 10.0 13.0 0.13 12.5 6.3 2.5 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Dynamin_N PF00350.23 EIM92548.1 - 1.1 9.3 6.3 0.12 12.5 0.6 2.2 2 1 1 3 3 3 0 Dynamin family Alginate_lyase PF05426.12 EIM92549.1 - 3.8e-53 180.8 3.0 4e-51 174.2 0.3 2.2 2 0 0 2 2 2 2 Alginate lyase Arrestin_C PF02752.22 EIM92550.1 - 0.085 13.3 1.2 0.23 11.9 1.2 1.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain ARID PF01388.21 EIM92551.1 - 5.9e-15 55.7 0.0 8.5e-14 52.0 0.0 2.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 EIM92551.1 - 0.0011 18.3 0.2 0.02 14.2 0.1 2.7 2 1 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa DUF1764 PF08576.10 EIM92552.1 - 5.4e-11 43.3 8.1 1.2e-08 35.8 0.7 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Ndc1_Nup PF09531.10 EIM92552.1 - 0.64 8.6 1.8 0.61 8.7 1.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.19 EIM92552.1 - 0.79 10.3 11.0 5.2 7.7 0.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAD-oxidase_C PF02913.19 EIM92553.1 - 1.4e-57 195.2 0.0 1.7e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EIM92553.1 - 4.8e-33 113.8 2.1 1.2e-32 112.6 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain BRCT_2 PF16589.5 EIM92554.1 - 1.6e-11 44.4 0.0 0.00024 21.5 0.0 2.4 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EIM92554.1 - 1e-09 38.4 1.7 2.8e-09 37.0 1.7 1.7 1 0 0 1 1 1 1 Rap1 Myb domain 2OG-FeII_Oxy_2 PF13532.6 EIM92554.1 - 0.25 11.5 1.3 0.61 10.2 1.3 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Rap1-DNA-bind PF09197.10 EIM92554.1 - 2.2 8.9 5.7 1.9 9.1 2.6 2.5 2 1 0 2 2 2 0 Rap1, DNA-binding Androgen_recep PF02166.16 EIM92554.1 - 5.3 5.8 11.7 0.29 9.9 0.8 2.3 2 0 0 2 2 2 0 Androgen receptor Pkinase PF00069.25 EIM92555.1 - 1.8e-67 227.5 0.0 2.2e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92555.1 - 1.1e-25 90.4 0.0 1.3e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM92555.1 - 9e-06 25.2 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EIM92555.1 - 0.0044 16.6 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EIM92555.1 - 0.16 10.9 0.1 0.29 10.0 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain MMM1 PF10296.9 EIM92556.1 - 1.6e-37 129.3 0.2 1.5e-19 70.3 0.0 3.0 1 1 2 3 3 3 3 Maintenance of mitochondrial morphology protein 1 DDE_Tnp_4 PF13359.6 EIM92557.1 - 3e-18 66.0 0.0 4.2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 EIM92557.1 - 6.4e-06 25.9 0.1 0.00041 20.0 0.1 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 EIM92557.1 - 0.00015 21.5 0.0 0.0022 17.7 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain LXG PF04740.12 EIM92558.1 - 0.052 13.3 0.4 0.13 11.9 0.2 1.7 1 1 0 1 1 1 0 LXG domain of WXG superfamily Trypsin_2 PF13365.6 EIM92559.1 - 0.00082 20.3 0.0 0.08 13.8 0.0 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EIM92559.1 - 0.021 14.6 0.3 0.24 11.1 0.0 2.5 3 0 0 3 3 3 0 Trypsin Peptidase_S3 PF00944.19 EIM92559.1 - 0.034 14.0 0.1 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Alphavirus core protein Peptidase_S32 PF05579.13 EIM92559.1 - 0.041 13.1 0.1 0.063 12.5 0.1 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 EIM92559.1 - 0.35 9.5 4.1 1.2 7.7 0.2 2.1 2 0 0 2 2 2 0 Peptidase S46 AAA_23 PF13476.6 EIM92559.1 - 0.43 11.1 4.0 0.65 10.5 4.0 1.2 1 0 0 1 1 1 0 AAA domain L_biotic_typeA PF04604.13 EIM92560.1 - 0.048 13.5 0.1 0.71 9.8 0.1 2.5 2 0 0 2 2 2 0 Type-A lantibiotic RNA_pol_Rpb8 PF03870.15 EIM92561.1 - 4.2e-47 159.8 0.0 4.7e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Pkinase PF00069.25 EIM92562.1 - 9e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92562.1 - 0.0035 16.7 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EIM92562.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EIM92562.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EIM92562.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EIM92562.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zinc_ribbon_4 PF13717.6 EIM92562.1 - 0.15 12.0 0.2 0.34 10.9 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain ActA PF05058.12 EIM92563.1 - 0.95 7.7 5.1 1.2 7.4 5.1 1.1 1 0 0 1 1 1 0 ActA Protein GYF PF02213.16 EIM92564.1 - 2e-15 56.2 0.0 4.5e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EIM92564.1 - 0.0054 16.5 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 GYF domain 2 AMP-binding PF00501.28 EIM92565.1 - 5.1e-73 246.1 0.1 8.6e-73 245.3 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Cellulase PF00150.18 EIM92565.1 - 1.1e-49 169.4 0.0 2.3e-49 168.4 0.0 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AMP-binding_C PF13193.6 EIM92565.1 - 2.4e-21 76.5 0.1 6.5e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBM_1 PF00734.18 EIM92565.1 - 2.1e-11 43.6 13.2 5.1e-11 42.3 13.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Complex1_LYR PF05347.15 EIM92566.1 - 0.00017 21.6 2.6 0.00038 20.4 2.6 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EIM92566.1 - 0.55 11.0 3.5 0.39 11.5 1.0 2.0 3 0 0 3 3 3 0 Complex1_LYR-like Sec8_exocyst PF04048.14 EIM92567.1 - 3.2e-35 121.1 0.6 6.2e-35 120.2 0.6 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EIM92567.1 - 1.8e-07 30.7 0.2 3.3e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex HDV_ag PF01517.18 EIM92567.1 - 0.021 14.6 3.6 0.046 13.5 3.6 1.5 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen DUF3496 PF12001.8 EIM92567.1 - 0.041 14.3 0.5 4.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) LIDHydrolase PF10230.9 EIM92568.1 - 7.1e-46 156.9 0.0 8.5e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EIM92568.1 - 2.8e-05 24.8 2.8 2.8e-05 24.8 2.8 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIM92568.1 - 0.0099 15.2 0.0 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 EIM92568.1 - 0.025 14.1 0.0 0.058 12.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_25 PF13649.6 EIM92569.1 - 9.1e-06 26.3 0.0 0.00044 20.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain SNF2_N PF00176.23 EIM92570.1 - 3.4e-58 197.0 0.1 5.5e-58 196.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIM92570.1 - 1.8e-19 70.1 0.0 4.6e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EIM92570.1 - 1.7e-16 60.2 0.2 1.7e-16 60.2 0.2 1.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 EIM92570.1 - 1.1e-07 31.7 12.7 1.3e-06 28.1 0.7 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.24 EIM92570.1 - 2.7e-05 24.0 1.0 0.08 12.9 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ERCC3_RAD25_C PF16203.5 EIM92570.1 - 3.5e-05 23.1 0.0 8.3e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EIM92570.1 - 3.9e-05 23.7 0.0 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KRAB PF01352.27 EIM92570.1 - 0.083 12.5 0.2 0.29 10.8 0.2 1.9 1 0 0 1 1 1 0 KRAB box zinc_ribbon_5 PF13719.6 EIM92570.1 - 0.2 11.5 1.5 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Cytochrome_C7 PF14522.6 EIM92570.1 - 2.4 8.2 6.7 0.89 9.6 2.6 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Ribonucleas_3_3 PF14622.6 EIM92571.1 - 8.8e-07 29.1 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIM92571.1 - 0.011 16.4 0.0 0.045 14.4 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease III domain Glyco_hydro_20 PF00728.22 EIM92572.1 - 3e-27 96.0 0.1 3.3e-20 72.8 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EIM92572.1 - 2e-13 51.2 0.1 1.2e-12 48.7 0.1 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Ima1_N PF09779.9 EIM92573.1 - 3.7e-32 112.0 3.2 5.3e-32 111.5 3.2 1.2 1 0 0 1 1 1 1 Ima1 N-terminal domain TFIIA PF03153.13 EIM92574.1 - 0.52 10.2 16.9 0.66 9.9 16.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 EIM92574.1 - 0.96 7.9 21.1 1.2 7.6 21.1 1.1 1 0 0 1 1 1 0 Utp14 protein RR_TM4-6 PF06459.12 EIM92574.1 - 1.8 8.3 9.4 3 7.6 9.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hepar_II_III PF07940.13 EIM92575.1 - 1.8e-08 34.3 1.1 3.3e-08 33.5 1.1 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein Thiolase_N PF00108.23 EIM92576.1 - 1.7e-69 234.1 1.0 3.1e-69 233.2 1.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIM92576.1 - 4.9e-46 155.4 1.1 1.4e-45 153.9 1.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 EIM92576.1 - 7.5e-05 22.8 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EIM92576.1 - 0.00036 20.3 0.5 0.046 13.6 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EIM92576.1 - 0.00046 19.8 2.1 0.0015 18.1 0.6 2.7 4 1 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain Cpn60_TCP1 PF00118.24 EIM92577.1 - 5.7e-165 549.6 4.1 6.5e-165 549.5 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 EIM92577.1 - 0.09 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TatD_DNase PF01026.21 EIM92578.1 - 2.4e-49 168.0 0.0 3e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Glyco_hydro_43 PF04616.14 EIM92579.1 - 5.1e-60 203.2 6.0 6.7e-60 202.8 6.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EIM92579.1 - 3.4e-24 85.7 0.3 1.6e-23 83.5 0.3 1.9 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_transf_21 PF13506.6 EIM92580.1 - 2.1e-25 89.2 0.6 4e-21 75.3 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EIM92580.1 - 1.8e-14 54.2 0.0 2.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIM92580.1 - 5.4e-07 29.6 0.0 8.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sec3_C PF09763.9 EIM92581.1 - 5.2e-165 550.7 6.6 7.2e-165 550.2 6.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EIM92581.1 - 3e-18 65.7 0.0 7.3e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 EIM92581.1 - 3.7e-06 26.0 8.4 0.00057 18.8 2.1 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family Exo70 PF03081.15 EIM92581.1 - 0.0047 16.0 4.0 0.0053 15.8 2.3 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Methyltransf_FA PF12248.8 EIM92581.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Rab5-bind PF09311.11 EIM92581.1 - 0.13 11.6 7.6 0.072 12.5 4.1 2.1 2 0 0 2 2 2 0 Rabaptin-like protein DUF4279 PF14106.6 EIM92581.1 - 0.24 11.6 1.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) End3 PF12761.7 EIM92581.1 - 0.57 10.3 5.0 0.38 10.9 0.6 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FUSC PF04632.12 EIM92581.1 - 5.2 5.5 7.1 15 4.0 6.8 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family TB2_DP1_HVA22 PF03134.19 EIM92582.1 - 2.6e-26 91.4 8.1 2.6e-26 91.4 8.1 1.6 1 1 1 2 2 2 2 TB2/DP1, HVA22 family GtrA PF04138.14 EIM92582.1 - 0.015 15.5 2.5 0.02 15.2 2.5 1.4 1 1 0 1 1 1 0 GtrA-like protein Zn_clus PF00172.18 EIM92583.1 - 2.2e-07 30.9 10.6 3.9e-07 30.1 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIM92583.1 - 0.00035 19.7 0.0 0.001 18.2 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_pp85 PF04637.12 EIM92583.1 - 8.2 4.7 6.0 0.32 9.4 0.1 1.5 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ribosomal_S16 PF00886.19 EIM92584.1 - 2.3e-16 59.6 0.1 3.1e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.19 EIM92585.1 - 9.2e-15 54.6 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 EIM92585.1 - 1.6e-09 37.9 0.1 2.5e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIM92585.1 - 1.1e-08 35.5 0.0 2.4e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EIM92585.1 - 4.3e-08 33.3 2.0 2.1e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EIM92585.1 - 4.5e-08 32.7 0.8 3.3e-06 27.0 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EIM92585.1 - 1.7e-07 31.7 0.2 3.1e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) CoA_binding PF02629.19 EIM92586.1 - 6.3e-30 103.7 1.2 9e-30 103.2 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EIM92586.1 - 2.3e-22 79.5 0.3 3.4e-22 78.9 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EIM92586.1 - 1.8e-08 34.3 0.2 4.1e-08 33.1 0.1 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EIM92586.1 - 2.7e-06 27.8 0.0 3.9e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 EIM92586.1 - 0.058 14.2 0.0 0.22 12.3 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Xpo1 PF08389.12 EIM92587.1 - 2.4e-21 76.4 0.1 8.3e-20 71.4 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EIM92587.1 - 5.9e-06 26.1 0.0 6.3e-05 22.8 0.1 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain TetR_C_30 PF17939.1 EIM92587.1 - 0.03 14.5 0.0 0.28 11.4 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HEAT_EZ PF13513.6 EIM92587.1 - 0.063 13.8 0.1 18 6.0 0.0 4.0 2 1 2 4 4 4 0 HEAT-like repeat Septin PF00735.18 EIM92588.1 - 8.6e-120 399.2 0.0 8.6e-120 399.2 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EIM92588.1 - 4.8e-08 33.1 0.1 2.6e-07 30.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EIM92588.1 - 0.00032 21.2 1.6 0.059 13.9 0.0 2.7 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 EIM92588.1 - 0.00073 19.5 0.3 0.00073 19.5 0.3 3.4 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EIM92588.1 - 0.0017 18.6 0.0 0.023 15.0 0.0 2.6 3 1 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 EIM92588.1 - 0.0017 18.4 2.8 1.6 8.8 0.0 3.3 2 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EIM92588.1 - 0.003 17.1 4.9 0.046 13.2 0.1 3.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EIM92588.1 - 0.005 16.2 0.2 0.019 14.3 0.0 2.0 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 EIM92588.1 - 0.0091 16.4 0.1 0.059 13.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 EIM92588.1 - 0.012 15.3 0.0 0.069 12.8 0.0 2.3 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.6 EIM92588.1 - 0.034 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Exonuc_VII_L PF02601.15 EIM92588.1 - 0.55 9.8 5.2 0.85 9.1 5.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS6_N PF14661.6 EIM92588.1 - 0.61 9.6 8.3 1 8.9 8.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.9 EIM92588.1 - 1.8 7.6 6.6 2.6 7.0 6.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP_bind_1 PF03029.17 EIM92588.1 - 1.9 8.2 5.5 9.3 5.9 0.0 3.3 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.11 EIM92588.1 - 2.5 8.2 11.7 0.26 11.3 3.7 2.5 1 1 1 2 2 2 0 Streptococcal surface antigen repeat TetR_C_28 PF17937.1 EIM92589.1 - 0.061 13.8 2.4 0.067 13.6 0.8 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CN_hydrolase PF00795.22 EIM92590.1 - 2.6e-53 181.0 0.0 2.9e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.9 EIM92591.1 - 2.5e-33 115.2 0.0 3.7e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.13 EIM92592.1 - 1.3e-56 190.8 0.1 1.5e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 EIM92592.1 - 1.6 8.7 5.3 25 4.9 5.3 2.3 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Pkinase PF00069.25 EIM92594.1 - 1.5e-66 224.5 0.0 1.9e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92594.1 - 3.2e-45 154.4 0.0 4.8e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIM92594.1 - 3.9e-10 39.5 0.2 2.5e-06 27.1 0.0 2.4 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EIM92594.1 - 8.6e-06 24.8 0.0 1.5e-05 23.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EIM92594.1 - 8.1e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIM92594.1 - 0.011 15.7 0.0 0.032 14.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIM92594.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EIM92594.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EIM92594.1 - 0.098 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 EIM92594.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 RIO1 family CLTH PF10607.9 EIM92595.1 - 4.3e-34 117.5 0.2 5.3e-34 117.3 0.2 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EIM92595.1 - 0.00013 21.8 0.2 0.00029 20.7 0.2 1.6 1 0 0 1 1 1 1 LisH TINF2_N PF14973.6 EIM92595.1 - 0.071 13.5 0.1 0.39 11.0 0.0 2.0 1 1 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF3164 PF11363.8 EIM92595.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) Rrp15p PF07890.12 EIM92596.1 - 1.2e-29 103.4 3.8 1.2e-29 103.4 3.8 1.9 1 1 1 2 2 2 1 Rrp15p DIL PF01843.19 EIM92597.1 - 4.7e-28 97.5 2.0 9.4e-28 96.5 2.0 1.5 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 EIM92597.1 - 9.3e-08 32.5 0.1 3.2e-06 27.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM92597.1 - 6e-07 30.0 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIM92597.1 - 6.1e-06 26.4 0.0 2.3e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EIM92597.1 - 2.8e-05 24.3 1.0 0.05 14.1 0.2 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EIM92597.1 - 0.00021 21.5 1.6 0.024 15.1 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat PROL5-SMR PF15621.6 EIM92598.1 - 0.61 10.6 6.3 0.3 11.6 0.6 2.4 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Transpos_assoc PF13963.6 EIM92598.1 - 0.71 10.2 6.0 0.4 11.0 0.7 2.5 1 1 2 3 3 3 0 Transposase-associated domain Rhomboid PF01694.22 EIM92599.1 - 7.6e-27 94.2 15.7 1.3e-26 93.4 15.7 1.4 1 0 0 1 1 1 1 Rhomboid family 3Beta_HSD PF01073.19 EIM92600.1 - 7.9e-08 31.6 0.0 2.1e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIM92600.1 - 1.2e-07 31.4 0.2 4e-05 23.2 0.2 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIM92600.1 - 1.8e-07 31.3 0.1 3.3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EIM92600.1 - 0.0004 20.8 0.2 0.00099 19.5 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EIM92600.1 - 0.0017 18.3 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EIM92600.1 - 0.017 14.7 0.1 0.039 13.5 0.1 1.6 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EIM92600.1 - 0.028 13.8 0.1 0.071 12.5 0.1 1.7 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM92600.1 - 0.053 12.7 0.1 0.085 12.0 0.1 1.5 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 EIM92600.1 - 0.1 11.7 0.1 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EIM92601.1 - 7.9e-09 34.9 0.0 1.7e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIM92601.1 - 3.2e-08 33.7 0.3 6e-08 32.8 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIM92601.1 - 3.6e-08 33.2 0.2 6.9e-06 25.7 0.2 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EIM92601.1 - 0.00024 21.5 0.1 0.0012 19.2 0.0 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EIM92601.1 - 0.00045 19.8 0.1 0.001 18.7 0.1 1.6 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EIM92601.1 - 0.004 17.1 0.1 0.0059 16.5 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EIM92601.1 - 0.0043 16.5 0.1 0.012 15.0 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EIM92601.1 - 0.033 13.4 0.1 0.075 12.2 0.0 1.7 2 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 EIM92601.1 - 0.036 13.2 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Cas1_AcylT PF07779.12 EIM92602.1 - 6.4e-142 473.8 19.5 9.2e-142 473.3 19.5 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 EIM92602.1 - 0.0045 16.8 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Cut8 PF08559.10 EIM92603.1 - 3.9e-15 56.1 0.0 2.4e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein TPR_14 PF13428.6 EIM92604.1 - 0.036 14.9 1.2 4.5 8.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RNase_T PF00929.24 EIM92605.1 - 0.03 14.9 0.0 0.12 12.9 0.0 1.9 1 1 0 1 1 1 0 Exonuclease DNA_pol_A_exo1 PF01612.20 EIM92605.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease Mito_carr PF00153.27 EIM92606.1 - 3.2e-46 155.2 0.5 5.9e-15 55.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MHC2-interact PF09307.10 EIM92607.1 - 0.051 13.6 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 CLIP, MHC2 interacting DAZAP2 PF11029.8 EIM92607.1 - 0.067 14.1 0.1 0.087 13.8 0.1 1.2 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) LSM PF01423.22 EIM92608.1 - 1.5e-20 72.7 0.1 1.7e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 EIM92608.1 - 0.16 12.1 0.0 0.2 11.8 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain Arm PF00514.23 EIM92609.1 - 8.3e-92 298.8 13.2 3.3e-12 46.0 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EIM92609.1 - 3e-24 85.3 5.4 5.5e-24 84.4 5.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 EIM92609.1 - 4.7e-22 78.1 2.2 2.9e-08 34.0 0.0 5.8 3 1 3 6 6 6 3 HEAT-like repeat Arm_3 PF16186.5 EIM92609.1 - 5e-22 77.2 0.8 1.2e-21 76.0 0.8 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 EIM92609.1 - 6.2e-17 61.8 0.6 3.1e-05 24.3 0.0 5.4 2 1 5 7 7 7 4 HEAT repeats HEAT PF02985.22 EIM92609.1 - 6.8e-15 53.9 0.8 0.00031 20.7 0.0 6.5 7 0 0 7 7 6 3 HEAT repeat Adaptin_N PF01602.20 EIM92609.1 - 3.5e-06 25.9 0.0 0.00081 18.1 0.0 2.9 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.6 EIM92609.1 - 4.1e-06 26.9 1.2 0.0065 16.7 0.0 4.2 3 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 EIM92609.1 - 1.4e-05 24.7 0.1 0.053 13.0 0.0 3.9 2 1 2 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.8 EIM92609.1 - 0.00035 20.7 0.2 1.4 9.0 0.0 4.2 3 3 3 6 6 6 2 V-ATPase subunit H HEAT_PBS PF03130.16 EIM92609.1 - 0.0011 19.4 0.5 0.71 10.7 0.0 4.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 EIM92609.1 - 0.023 14.1 0.0 0.097 12.0 0.0 2.0 2 0 0 2 2 2 0 Mo25-like V-ATPase_H_N PF03224.14 EIM92609.1 - 0.031 13.6 0.0 4.4 6.5 0.0 3.0 1 1 1 2 2 2 0 V-ATPase subunit H RNF111_N PF15303.6 EIM92609.1 - 0.13 12.0 1.1 0.2 11.4 1.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus RPN2_C PF18004.1 EIM92610.1 - 6.3e-45 153.0 1.9 1e-41 142.5 2.1 2.3 2 0 0 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EIM92610.1 - 5.7e-32 108.5 22.4 2.1e-08 34.2 0.0 9.5 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EIM92610.1 - 1.5e-17 63.8 3.4 9.4e-15 54.8 0.0 4.3 3 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 EIM92610.1 - 3.8e-05 23.6 0.4 3.5 8.1 0.1 4.0 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EIM92610.1 - 0.00074 20.0 1.1 0.81 10.3 0.0 4.3 2 1 2 4 4 4 2 HEAT-like repeat RPN1_RPN2_N PF17781.1 EIM92610.1 - 0.015 14.7 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Pox_Ag35 PF03286.14 EIM92610.1 - 0.027 14.3 3.0 0.053 13.3 3.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Adaptin_N PF01602.20 EIM92610.1 - 0.14 10.7 0.1 0.64 8.5 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_PBS PF03130.16 EIM92610.1 - 0.31 11.8 1.2 3.2e+02 2.5 0.0 4.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat COX6A PF02046.15 EIM92611.1 - 1.3e-30 106.1 0.2 1.5e-30 105.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa fn3_4 PF16794.5 EIM92611.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Fibronectin-III type domain Psu PF07455.11 EIM92612.1 - 0.089 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) Wzy_C_2 PF11846.8 EIM92612.1 - 2.7 7.9 6.7 0.31 10.9 1.6 1.9 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Helicase_C PF00271.31 EIM92613.1 - 1.1e-15 57.9 0.0 3.2e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM92613.1 - 1.6e-14 54.1 0.0 2.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EIM92613.1 - 7.3e-08 33.0 0.1 1.6e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding PAC2 PF09754.9 EIM92613.1 - 0.11 12.4 0.0 2.6 8.0 0.0 2.7 2 1 0 2 2 2 0 PAC2 family Nucleoporin_N PF08801.11 EIM92614.1 - 1.3e-62 212.0 0.0 1.9e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EIM92614.1 - 1.9e-38 132.6 0.4 2.8e-38 132.1 0.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal vATP-synt_AC39 PF01992.16 EIM92614.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit DUF4598 PF15370.6 EIM92615.1 - 2.6e-15 56.8 0.1 4.2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Helicase_Sgs1 PF11408.8 EIM92615.1 - 0.08 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Sgs1 RecQ helicase zf-CSL PF05207.13 EIM92616.1 - 4.2e-13 48.8 0.4 6.6e-13 48.2 0.4 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EIM92616.1 - 1.2e-09 38.1 0.1 1.9e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Exo5 PF09810.9 EIM92617.1 - 3.9e-69 233.9 0.5 1.2e-57 196.2 0.3 3.1 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.20 EIM92617.1 - 0.0018 18.1 0.8 0.0059 16.5 0.8 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif SAGA-Tad1 PF12767.7 EIM92617.1 - 0.038 13.7 1.8 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit S8_pro-domain PF16470.5 EIM92617.1 - 0.26 12.1 1.5 1.1 10.1 0.3 2.7 1 1 1 2 2 2 0 Peptidase S8 pro-domain Ctr PF04145.15 EIM92618.1 - 0.0013 19.3 5.4 0.0013 19.3 5.4 2.4 2 1 1 3 3 3 1 Ctr copper transporter family MFS_1 PF07690.16 EIM92619.1 - 4.1e-12 45.7 52.0 6.9e-07 28.5 33.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4662 PF15578.6 EIM92619.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) S1FA PF04689.13 EIM92619.1 - 0.7 10.1 1.8 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA Pkinase PF00069.25 EIM92620.1 - 6.3e-38 130.7 0.0 9.3e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92620.1 - 2.1e-26 92.7 0.0 3e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM92620.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EIM92620.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NAD_binding_2 PF03446.15 EIM92621.1 - 2.1e-22 80.0 0.0 4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EIM92621.1 - 1.1e-07 32.2 0.1 2.1e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EIM92621.1 - 1.3e-06 28.5 0.0 3.1e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EIM92621.1 - 8e-05 23.1 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Exo_endo_phos PF03372.23 EIM92622.1 - 4.1e-16 59.2 0.0 6.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Adaptin_N PF01602.20 EIM92623.1 - 1.3e-112 377.1 0.0 1.9e-112 376.5 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EIM92623.1 - 1.9e-57 193.7 0.6 3.8e-57 192.7 0.6 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EIM92623.1 - 4.2e-35 120.3 0.0 9.7e-35 119.2 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EIM92623.1 - 1.2e-16 60.9 3.0 6.3e-10 39.3 0.0 5.7 3 3 3 6 6 6 3 HEAT repeats Cnd1 PF12717.7 EIM92623.1 - 4.9e-08 33.2 3.6 0.016 15.2 0.1 4.5 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIM92623.1 - 0.016 15.4 7.0 19 5.9 0.3 6.1 6 0 0 6 6 6 0 HEAT repeat Arm PF00514.23 EIM92623.1 - 0.043 13.9 0.3 28 4.9 0.1 4.2 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EIM92623.1 - 0.078 13.7 2.2 11 7.1 0.1 4.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EIM92623.1 - 3.3 8.3 6.2 4.3 7.9 0.6 3.7 4 1 0 4 4 4 0 HEAT-like repeat Fumble PF03630.14 EIM92624.1 - 5.4e-130 433.4 0.0 7.3e-130 433.0 0.0 1.2 1 0 0 1 1 1 1 Fumble Homeodomain PF00046.29 EIM92625.1 - 3.8e-45 151.6 14.9 7.4e-16 57.7 0.4 3.5 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 EIM92625.1 - 3.7e-14 52.3 3.0 4.8e-06 26.4 0.1 3.6 3 0 0 3 3 3 3 Homeobox KN domain HOCHOB PF17943.1 EIM92625.1 - 1.3e-07 32.3 0.0 0.15 12.8 0.0 3.3 3 0 0 3 3 3 3 Homeobox-cysteine loop-homeobox YdaS_antitoxin PF15943.5 EIM92625.1 - 5.3e-06 26.2 0.3 0.052 13.4 0.1 3.3 3 0 0 3 3 3 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 EIM92625.1 - 0.0027 17.7 0.5 1.6 8.8 0.1 3.3 3 0 0 3 3 3 1 Helix-turn-helix Homez PF11569.8 EIM92625.1 - 0.0078 15.7 0.4 4.9 6.7 0.0 3.0 3 0 0 3 3 3 2 Homeodomain leucine-zipper encoding, Homez RRF PF01765.19 EIM92625.1 - 0.21 11.5 2.0 10 6.0 0.8 2.3 2 0 0 2 2 2 0 Ribosome recycling factor Aldo_ket_red PF00248.21 EIM92627.1 - 4.7e-49 167.2 0.0 5.3e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YCII PF03795.14 EIM92627.1 - 0.033 14.6 0.0 0.56 10.6 0.0 2.3 2 0 0 2 2 2 0 YCII-related domain Mannosidase_ig PF17786.1 EIM92628.1 - 3.9e-16 59.4 0.1 1.8e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EIM92628.1 - 2e-08 34.9 0.0 6.8e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Bacteriocin_IIc PF10439.9 EIM92630.1 - 0.2 11.8 1.4 0.32 11.1 1.4 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Cytotoxic PF09000.10 EIM92631.1 - 0.048 14.0 1.8 0.69 10.3 0.3 2.3 1 1 1 2 2 2 0 Cytotoxic HA2 PF04408.23 EIM92632.1 - 1.3e-21 76.9 0.0 4.9e-21 75.0 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIM92632.1 - 8e-15 55.0 0.0 1.8e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIM92632.1 - 7.4e-12 45.6 0.1 2.2e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIM92632.1 - 2.1e-10 40.6 0.5 5e-10 39.4 0.5 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EIM92632.1 - 0.0081 15.3 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EIM92632.1 - 0.0082 16.4 0.2 0.027 14.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM92632.1 - 0.014 15.7 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain UBA PF00627.31 EIM92632.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain NACHT PF05729.12 EIM92632.1 - 0.12 12.2 0.2 0.4 10.6 0.2 1.9 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.16 EIM92632.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein HA2 PF04408.23 EIM92633.1 - 2.8e-25 88.7 0.1 8.3e-25 87.2 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIM92633.1 - 3.4e-23 81.8 0.0 6.7e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIM92633.1 - 9.3e-14 51.7 0.0 2.5e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EIM92633.1 - 3e-08 33.9 0.1 6.5e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EIM92633.1 - 1.9e-05 24.5 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIM92633.1 - 0.00017 21.8 0.0 0.00047 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EIM92633.1 - 0.00041 19.5 0.0 0.0009 18.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EIM92633.1 - 0.00061 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIM92633.1 - 0.0082 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIM92633.1 - 0.033 14.6 0.6 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EIM92633.1 - 0.051 14.1 0.4 3.4 8.2 0.1 3.0 2 1 0 2 2 2 0 ABC transporter DUF2075 PF09848.9 EIM92633.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Syntaxin-6_N PF09177.11 EIM92634.1 - 0.56 10.8 9.0 0.62 10.7 0.1 3.4 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Sec1 PF00995.23 EIM92635.1 - 4.3e-123 412.6 0.0 5.2e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family VitK2_biosynth PF02621.14 EIM92635.1 - 0.073 12.6 0.0 0.58 9.6 0.0 2.3 3 0 0 3 3 3 0 Menaquinone biosynthesis DUF2115 PF09888.9 EIM92635.1 - 0.13 12.8 0.0 0.38 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Qua1 PF16274.5 EIM92635.1 - 0.18 11.7 1.2 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Qua1 domain DnaJ PF00226.31 EIM92637.1 - 3.1e-20 72.1 4.0 5e-20 71.4 4.0 1.3 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_YMGG PF13441.6 EIM92637.1 - 0.056 13.2 14.9 0.28 10.9 8.0 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EIM92637.1 - 0.089 12.8 16.3 0.31 11.1 9.3 2.5 2 0 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.9 EIM92637.1 - 0.39 10.9 8.5 1.5 9.0 4.7 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide LIM PF00412.22 EIM92639.1 - 3.8e-15 55.8 20.4 4.9e-07 29.9 1.3 5.5 4 3 1 5 5 5 4 LIM domain OrfB_Zn_ribbon PF07282.11 EIM92639.1 - 4.4 7.3 5.6 22 5.1 0.0 4.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain FMN_dh PF01070.18 EIM92640.1 - 6.2e-111 370.8 0.0 8.1e-111 370.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EIM92640.1 - 3.4e-19 68.8 0.0 6.4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EIM92640.1 - 0.0001 21.6 0.0 0.00029 20.1 0.0 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EIM92640.1 - 0.00027 20.1 0.8 0.0016 17.5 0.1 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EIM92640.1 - 0.00063 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase UPF0767 PF15990.5 EIM92640.1 - 0.017 15.3 1.7 0.041 14.0 0.9 2.0 2 0 0 2 2 2 0 UPF0767 family ThiG PF05690.14 EIM92640.1 - 0.067 12.5 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG SAP PF02037.27 EIM92641.1 - 0.031 14.0 0.7 0.063 13.1 0.7 1.6 1 0 0 1 1 1 0 SAP domain HalOD1 PF18545.1 EIM92641.1 - 0.046 14.0 1.4 0.094 13.0 1.4 1.5 1 0 0 1 1 1 0 Halobacterial output domain 1 OmpH PF03938.14 EIM92641.1 - 0.46 10.8 1.8 0.78 10.1 1.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 EIM92642.1 - 2.3e-61 207.5 0.0 2.8e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92642.1 - 1.3e-23 83.6 0.0 2.3e-23 82.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIM92642.1 - 0.0018 17.3 0.1 0.0026 16.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIM92642.1 - 0.016 15.2 0.4 0.041 13.8 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EIM92642.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EIM92642.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribosomal_L22e PF01776.17 EIM92643.1 - 9.6e-46 154.7 1.8 1.1e-45 154.4 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DKCLD PF08068.12 EIM92644.1 - 2.6e-32 110.6 0.2 2.4e-31 107.6 0.4 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EIM92644.1 - 4.8e-23 82.2 0.2 2.4e-19 70.2 0.2 3.7 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EIM92644.1 - 5.6e-23 80.9 0.8 1.1e-22 80.0 0.8 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EIM92644.1 - 2.1e-21 75.7 1.7 4.3e-21 74.6 1.7 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EIM92644.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain SR-25 PF10500.9 EIM92644.1 - 0.068 12.8 19.0 0.12 11.9 19.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.11 EIM92644.1 - 0.53 10.4 29.0 1.2 9.2 29.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Smg8_Smg9 PF10220.9 EIM92644.1 - 1 7.6 10.0 1.3 7.2 10.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 SAPS PF04499.15 EIM92644.1 - 1.1 8.0 5.3 1.5 7.5 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 EIM92644.1 - 1.4 9.2 9.6 2.1 8.5 9.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Connexin PF00029.19 EIM92644.1 - 2.9 7.6 6.6 6.4 6.5 6.6 1.5 1 0 0 1 1 1 0 Connexin Cyclin_C_2 PF16899.5 EIM92646.1 - 3.5e-18 65.9 1.3 1.3e-15 57.7 0.1 2.9 3 0 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EIM92646.1 - 2.4e-10 40.2 0.1 1.4e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EIM92646.1 - 0.0026 17.7 0.0 0.0083 16.1 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EIM92646.1 - 0.25 11.4 1.5 2.2 8.4 0.1 2.9 2 1 1 3 3 3 0 Cyclin, C-terminal domain Ribosomal_L13 PF00572.18 EIM92647.1 - 1.3e-11 44.8 0.1 5.9e-10 39.5 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L13 PP-binding PF00550.25 EIM92648.1 - 1.2e-14 54.3 0.2 1.7e-14 53.9 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EIM92648.1 - 2.7e-06 27.5 0.2 3.6e-06 27.1 0.2 1.1 1 0 0 1 1 1 1 Acyl-carrier SGL PF08450.12 EIM92649.1 - 2e-63 214.2 0.0 2.9e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EIM92649.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Arylesterase PD40 PF07676.12 EIM92649.1 - 0.0069 16.3 0.2 0.016 15.1 0.2 1.6 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EIM92649.1 - 0.043 14.1 0.0 9.1 6.7 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EIM92649.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ribosomal_L17 PF01196.19 EIM92650.1 - 4.5e-34 117.2 0.1 3.3e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 DcrB PF08786.11 EIM92652.1 - 0.08 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 DcrB Sin_N PF04801.13 EIM92653.1 - 1.9e-27 96.6 0.0 2.5e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region HA2 PF04408.23 EIM92654.1 - 2.8e-16 59.7 0.0 1.1e-15 57.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIM92654.1 - 8.2e-15 55.1 0.0 2.1e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EIM92654.1 - 2.6e-11 43.7 0.0 5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EIM92654.1 - 1.7e-06 27.9 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIM92654.1 - 2.3e-06 27.9 0.1 7.5e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EIM92654.1 - 0.0085 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 EIM92654.1 - 0.068 13.7 0.1 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 EIM92654.1 - 0.16 11.3 0.6 0.84 8.9 0.0 2.1 2 0 0 2 2 2 0 KaiC SNF2_N PF00176.23 EIM92655.1 - 4.2e-66 223.1 4.4 7.8e-66 222.2 4.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EIM92655.1 - 2.1e-44 151.1 17.5 2.1e-44 151.1 17.5 3.0 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 EIM92655.1 - 2.2e-16 60.2 0.0 4.9e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM92655.1 - 1.4e-07 31.6 0.0 4.2e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIM92655.1 - 0.0001 21.6 4.0 0.00038 19.7 0.0 2.9 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Lyase_1 PF00206.20 EIM92656.1 - 2.5e-118 395.0 0.0 3.3e-118 394.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EIM92656.1 - 3.6e-19 68.9 0.1 8.2e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EIM92656.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PEX11 PF05648.14 EIM92657.1 - 5.2e-50 170.0 1.4 5.9e-50 169.8 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cmc1 PF08583.10 EIM92658.1 - 3.1e-11 43.1 1.3 3.8e-11 42.8 1.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like LIAS_N PF16881.5 EIM92659.1 - 4.6e-25 88.1 0.0 2.6e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EIM92659.1 - 1.7e-14 54.5 0.0 3.8e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily SET PF00856.28 EIM92660.1 - 1.8e-12 48.0 0.1 1e-11 45.5 0.1 2.2 1 1 0 1 1 1 1 SET domain CHAT PF12770.7 EIM92661.1 - 1.1e-29 103.8 0.0 1.6e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 CHAT domain Trypsin_2 PF13365.6 EIM92663.1 - 6.1e-09 36.9 0.1 1e-08 36.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Glucosamine_iso PF01182.20 EIM92665.1 - 7.1e-74 248.5 0.0 8e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GspH PF12019.8 EIM92665.1 - 0.2 12.1 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II transport protein GspH GFO_IDH_MocA PF01408.22 EIM92666.1 - 7.8e-12 46.1 0.7 5.4e-11 43.4 0.7 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EIM92666.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA_C PF02894.17 EIM92666.1 - 0.0098 15.9 0.2 0.047 13.7 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.6 EIM92666.1 - 0.021 15.3 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Cyclin_N PF00134.23 EIM92668.1 - 2.7e-38 130.6 0.5 7.6e-38 129.1 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIM92668.1 - 1.9e-09 37.6 0.3 1.2e-08 35.1 0.2 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain SPT16 PF08644.11 EIM92670.1 - 4.2 7.6 9.4 5 7.3 3.0 2.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Complex1_LYR PF05347.15 EIM92671.1 - 6e-13 48.6 0.7 7.2e-13 48.4 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EIM92671.1 - 0.0096 16.5 0.2 0.014 16.0 0.2 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Acyl-CoA_dh_1 PF00441.24 EIM92671.1 - 0.023 14.9 0.2 0.026 14.7 0.2 1.0 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain RdRP PF05183.12 EIM92672.1 - 2.2e-157 525.2 0.0 2.7e-157 525.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF2744 PF10910.8 EIM92672.1 - 0.11 12.4 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) Sec7 PF01369.20 EIM92673.1 - 1.1e-31 109.9 0.0 1.9e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EIM92673.1 - 1.7e-11 44.5 0.0 3.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EIM92673.1 - 4.4e-09 36.8 0.0 1.2e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 PH domain Hist_deacetyl PF00850.19 EIM92675.1 - 2.4e-85 286.7 0.0 3.2e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 EIM92675.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NIL domain 2OG-FeII_Oxy_3 PF13640.6 EIM92677.1 - 2.9e-13 50.5 0.0 5.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EIM92677.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Herpes_UL1 PF05259.11 EIM92677.1 - 0.062 13.4 0.0 4.1 7.5 0.0 2.8 2 1 1 3 3 3 0 Herpesvirus glycoprotein L XPA_C PF05181.12 EIM92678.1 - 3.5e-24 84.5 0.6 6.7e-24 83.6 0.6 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EIM92678.1 - 2.6e-06 27.3 5.2 2.6e-06 27.3 5.2 2.4 3 0 0 3 3 3 1 XPA protein N-terminal 4HBT_3 PF13622.6 EIM92679.1 - 4.5e-54 184.3 0.1 5.2e-54 184.1 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EIM92679.1 - 1.2e-24 86.6 0.0 2.4e-20 72.7 0.0 3.1 2 2 1 3 3 3 2 Acyl-CoA thioesterase YqgC PF17430.2 EIM92679.1 - 1.8 8.7 3.5 16 5.6 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized YqgC-like Ribosomal_S27e PF01667.17 EIM92680.1 - 1.5e-28 98.2 1.7 1.9e-28 97.9 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EIM92680.1 - 0.12 11.9 1.6 0.19 11.3 1.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Mu-like_Com PF10122.9 EIM92680.1 - 0.91 9.0 4.6 10 5.7 0.9 2.4 1 1 1 2 2 2 0 Mu-like prophage protein Com BTG PF07742.12 EIM92681.1 - 2.1e-14 53.4 0.0 3.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 BTG family RAP1 PF07218.11 EIM92681.1 - 0.35 9.1 5.5 0.44 8.8 5.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.11 EIM92681.1 - 1.7 6.6 11.7 2.3 6.2 11.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 EIM92681.1 - 1.9 6.9 6.6 2.5 6.6 6.6 1.2 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 EIM92681.1 - 2.9 5.6 8.3 3.8 5.2 8.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NicO PF03824.16 EIM92684.1 - 5.6e-65 219.5 15.0 5.6e-65 219.5 15.0 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein BATS PF06968.13 EIM92685.1 - 8.7e-22 77.1 0.1 4.6e-21 74.8 0.0 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EIM92685.1 - 3.1e-15 57.0 0.0 5.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily MinE PF03776.14 EIM92687.1 - 0.0033 17.4 0.1 0.0077 16.2 0.1 1.7 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DUF3740 PF12548.8 EIM92687.1 - 0.038 14.4 0.5 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 Sulfatase protein BLM10_mid PF16507.5 EIM92688.1 - 3.8e-184 613.2 0.0 6.9e-184 612.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EIM92688.1 - 6.5e-32 109.3 0.1 4e-30 103.6 0.1 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 EIM92688.1 - 2.2e-06 27.4 7.8 0.0038 17.4 0.1 6.6 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 EIM92688.1 - 0.00012 22.4 7.1 0.00099 19.5 0.1 5.6 7 0 0 7 7 6 1 HEAT repeats TAF6_C PF07571.13 EIM92688.1 - 0.0027 18.0 0.1 0.21 11.9 0.1 3.4 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 EIM92688.1 - 0.0029 18.1 0.2 0.073 13.6 0.1 3.5 2 0 0 2 2 2 1 HEAT-like repeat Arm PF00514.23 EIM92688.1 - 0.0076 16.3 0.2 0.079 13.0 0.0 2.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 EIM92688.1 - 0.052 12.8 0.2 1.1 8.5 0.1 2.5 2 0 0 2 2 2 0 V-ATPase subunit H MyTH4 PF00784.17 EIM92688.1 - 0.062 13.8 0.7 2.7 8.5 0.0 3.7 4 0 0 4 4 4 0 MyTH4 domain CLASP_N PF12348.8 EIM92688.1 - 0.093 12.3 0.3 0.72 9.4 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal BLM10_N PF16547.5 EIM92688.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Cnd1 PF12717.7 EIM92688.1 - 0.14 12.2 0.1 0.99 9.4 0.1 2.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Nterm_IS4 PF13006.7 EIM92688.1 - 0.19 12.0 1.0 31 4.8 0.1 3.3 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal DcpS_C PF11969.8 EIM92689.1 - 0.00012 22.6 0.1 0.00035 21.0 0.1 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3875 PF12991.7 EIM92689.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) Translin PF01997.16 EIM92690.1 - 5.3e-38 131.1 0.0 6.5e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Translin family Hemopexin PF00045.19 EIM92690.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Hemopexin Pkinase PF00069.25 EIM92691.1 - 5.2e-66 222.7 0.0 7.9e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92691.1 - 2.9e-36 125.1 0.0 4e-26 91.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIM92691.1 - 0.0003 20.2 0.1 0.0023 17.3 0.1 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EIM92691.1 - 0.003 17.5 0.7 0.017 15.1 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIM92691.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EIM92691.1 - 0.038 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MMR_HSR1_Xtn PF16897.5 EIM92692.1 - 2.1e-42 143.4 1.5 4e-42 142.5 1.5 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EIM92692.1 - 3.3e-21 75.1 0.0 5.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EIM92692.1 - 9.3e-19 67.6 0.0 2.4e-18 66.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIM92692.1 - 3.3e-10 39.7 0.0 5.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EIM92692.1 - 0.0023 18.0 0.1 0.13 12.3 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MCM PF00493.23 EIM92692.1 - 0.042 12.9 0.1 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 EIM92692.1 - 0.044 14.2 0.2 0.094 13.1 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain Chromo PF00385.24 EIM92693.1 - 8.4e-05 22.4 1.5 0.00019 21.3 1.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MPS2 PF17060.5 EIM92693.1 - 0.09 12.0 3.2 0.16 11.2 3.2 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Med11 PF10280.9 EIM92694.1 - 1.1e-10 42.1 0.1 1.9e-10 41.3 0.1 1.4 1 1 0 1 1 1 1 Mediator complex protein TBCA PF02970.16 EIM92695.1 - 4e-23 81.6 4.1 4.7e-23 81.3 4.1 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Prominin PF05478.11 EIM92695.1 - 0.065 11.2 0.1 0.075 11.0 0.1 1.0 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 EIM92695.1 - 0.14 12.4 0.8 9.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HLH PF00010.26 EIM92696.1 - 1e-08 35.0 4.3 1e-08 35.0 4.3 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain UPF0242 PF06785.11 EIM92696.1 - 0.48 10.5 3.7 0.62 10.1 3.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MPC PF03650.13 EIM92697.1 - 0.29 11.3 1.8 0.76 9.9 1.6 1.9 1 1 0 1 1 1 0 Mitochondrial pyruvate carriers TRIQK PF15168.6 EIM92697.1 - 1.1 9.3 3.0 5 7.1 0.1 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family HLH PF00010.26 EIM92698.1 - 1e-10 41.4 1.5 1e-10 41.4 1.5 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LCE PF14672.6 EIM92698.1 - 0.005 17.4 3.0 0.005 17.4 3.0 2.3 2 0 0 2 2 2 1 Late cornified envelope DivIC PF04977.15 EIM92698.1 - 2.1 8.2 5.9 5.2 6.9 0.7 2.5 2 0 0 2 2 2 0 Septum formation initiator FAD_binding_4 PF01565.23 EIM92699.1 - 1.8e-18 66.6 0.1 3.4e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EIM92699.1 - 1.8e-06 28.0 0.5 4.6e-06 26.6 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like Het-C PF07217.11 EIM92702.1 - 6e-219 728.2 0.0 8.1e-219 727.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Pox_A32 PF04665.12 EIM92703.1 - 0.038 13.4 0.5 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.6 EIM92703.1 - 0.11 12.7 0.0 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EIM92703.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 EIM92703.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.9 EIM92703.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Bromodomain PF00439.25 EIM92704.1 - 2.6e-51 171.6 0.1 7.9e-16 57.9 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 EIM92704.1 - 5.6e-10 39.1 0.0 9.6e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EIM92704.1 - 0.00032 20.9 0.1 0.008 16.4 0.0 2.4 1 1 1 2 2 2 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 EIM92704.1 - 0.0058 17.0 6.1 7 7.1 0.2 4.9 5 0 0 5 5 5 2 HEAT repeats LTV PF04180.14 EIM92705.1 - 3.8e-106 356.1 13.5 6.5e-99 332.3 16.1 2.0 1 1 1 2 2 2 2 Low temperature viability protein PARP PF00644.20 EIM92706.1 - 3.3e-53 180.2 0.0 5.7e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EIM92706.1 - 1.2e-38 132.3 0.0 1.7e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EIM92706.1 - 3.7e-20 71.7 0.0 7.8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 WGR domain HMG_box_5 PF14887.6 EIM92706.1 - 0.19 11.7 1.4 0.44 10.5 1.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DHO_dh PF01180.21 EIM92707.1 - 1.8e-18 66.8 0.0 3.5e-08 33.0 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Vps39_2 PF10367.9 EIM92708.1 - 5.2 7.6 8.1 3 8.3 0.4 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 TRAPP PF04051.16 EIM92709.1 - 2.9e-42 143.9 0.0 3.5e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cullin PF00888.22 EIM92710.1 - 0.00061 18.5 0.0 0.00075 18.2 0.0 1.1 1 0 0 1 1 1 1 Cullin family DNA_pol_B PF00136.21 EIM92712.1 - 1.4e-100 337.2 0.0 1.8e-100 336.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EIM92712.1 - 2.5e-18 66.3 0.0 4.9e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EIM92712.1 - 3.8e-15 56.1 4.9 6.9e-15 55.3 4.9 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EIM92712.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DZR PF12773.7 EIM92712.1 - 0.79 9.8 3.7 1.8 8.6 3.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Aldose_epim PF01263.20 EIM92713.1 - 3.6e-34 118.4 0.0 4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pep3_Vps18 PF05131.14 EIM92714.1 - 3.8e-50 169.6 0.0 7.8e-50 168.6 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EIM92714.1 - 5.4e-10 39.3 3.5 0.00046 20.1 0.4 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EIM92714.1 - 7.3e-05 23.2 0.0 0.00022 21.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EIM92714.1 - 7.7e-05 22.6 2.8 0.00011 22.1 0.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIM92714.1 - 0.00072 19.3 1.8 0.00072 19.3 1.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM92714.1 - 0.0008 19.1 2.7 0.0008 19.1 2.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EIM92714.1 - 0.0019 18.5 1.0 0.0019 18.5 1.0 2.5 3 0 0 3 3 3 1 Ring finger domain Zn_ribbon_17 PF17120.5 EIM92714.1 - 0.004 16.8 0.6 0.004 16.8 0.6 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EIM92714.1 - 0.0067 16.4 3.1 0.01 15.9 1.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EIM92714.1 - 0.22 11.8 2.9 0.27 11.5 0.5 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EIM92714.1 - 1.5 8.8 4.6 0.61 10.0 1.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cgr1 PF03879.14 EIM92715.1 - 3.5e-28 98.1 18.6 4e-28 97.9 18.6 1.0 1 0 0 1 1 1 1 Cgr1 family PKcGMP_CC PF16808.5 EIM92716.1 - 0.15 11.9 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec39 PF08314.11 EIM92717.1 - 1e-93 315.2 0.0 1.4e-93 314.7 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 UPF0113_N PF17833.1 EIM92718.1 - 3.7e-30 104.3 0.0 5.7e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EIM92718.1 - 8.3e-26 90.1 0.0 1.8e-25 89.0 0.0 1.5 2 0 0 2 2 2 1 UPF0113 PUA domain HpuA PF16960.5 EIM92718.1 - 0.039 13.1 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter PP1 PF07430.11 EIM92718.1 - 0.051 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain p450 PF00067.22 EIM92719.1 - 1e-68 232.2 0.0 1.4e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Orthopox_F8 PF05886.11 EIM92719.1 - 0.13 12.4 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus F8 protein p450 PF00067.22 EIM92720.1 - 4.9e-66 223.4 0.0 6.7e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NRDE-2 PF08424.10 EIM92721.1 - 3.6e-63 213.6 1.1 3.6e-63 213.6 1.1 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 EIM92721.1 - 0.00016 21.0 1.5 0.084 12.1 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIM92721.1 - 0.0029 18.3 18.7 0.13 13.2 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIM92721.1 - 0.006 17.1 2.7 8.3 7.0 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat UreD PF01774.17 EIM92723.1 - 3.6e-67 226.4 0.0 4.2e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Aldedh PF00171.22 EIM92724.1 - 1.5e-124 416.0 0.0 1.8e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIM92724.1 - 7.6e-06 25.2 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HIGH_NTase1 PF05636.11 EIM92724.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase MFS_1 PF07690.16 EIM92725.1 - 2e-25 89.5 34.9 8.4e-25 87.4 35.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M41 PF01434.18 EIM92726.1 - 1.1e-60 204.8 0.0 1.6e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EIM92726.1 - 1.7e-42 144.9 0.0 3.3e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIM92726.1 - 5e-13 48.6 0.1 1.2e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EIM92726.1 - 8.2e-13 48.7 0.0 2.3e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_2 PF07724.14 EIM92726.1 - 0.0028 17.8 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EIM92726.1 - 0.0036 16.6 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EIM92726.1 - 0.0039 17.2 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIM92726.1 - 0.0047 16.7 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EIM92726.1 - 0.0085 16.5 1.2 0.059 13.7 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIM92726.1 - 0.014 15.7 0.1 0.5 10.6 0.1 2.7 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EIM92726.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ANAPC4_WD40 PF12894.7 EIM92727.1 - 9.7e-09 35.4 0.0 0.014 15.7 0.0 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM92727.1 - 9e-07 29.5 7.4 0.021 15.7 0.1 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 EIM92727.1 - 4.2e-05 23.5 0.0 0.84 9.5 0.1 4.6 6 1 0 6 6 6 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EIM92727.1 - 0.00062 17.9 0.0 0.0078 14.3 0.0 2.1 2 0 0 2 2 2 1 IKI3 family MFS_1 PF07690.16 EIM92728.1 - 9.5e-38 130.0 42.1 1.5e-37 129.4 36.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIM92728.1 - 1.2e-13 50.8 9.0 1.2e-13 50.8 9.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EIM92728.1 - 8e-11 41.1 1.3 8e-11 41.1 1.3 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EIM92728.1 - 2.8e-05 23.6 3.1 2.8e-05 23.6 3.1 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB G_glu_transpept PF01019.21 EIM92729.1 - 2.5e-143 478.5 0.0 2.9e-143 478.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Snf7 PF03357.21 EIM92730.1 - 7.6e-35 120.0 16.2 8.8e-35 119.8 16.2 1.0 1 0 0 1 1 1 1 Snf7 PT-HINT PF07591.11 EIM92730.1 - 0.11 12.7 0.2 0.18 12.1 0.2 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain Acyl-CoA_dh_C PF12806.7 EIM92730.1 - 1.1 9.5 5.5 2.4 8.3 0.6 2.5 1 1 2 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like RbsD_FucU PF05025.13 EIM92730.1 - 1.2 9.6 4.9 0.58 10.6 1.7 1.9 1 1 1 2 2 2 0 RbsD / FucU transport protein family PIEZO PF15917.5 EIM92730.1 - 4 6.9 8.0 8.8 5.7 2.7 2.1 2 0 0 2 2 2 0 Piezo DUF2481 PF10654.9 EIM92730.1 - 9 6.3 7.8 1.3 9.0 0.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2481) Pro_isomerase PF00160.21 EIM92731.1 - 6.5e-43 146.7 0.0 1.1e-42 146.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EIM92731.1 - 0.00023 20.6 0.4 0.0058 16.0 0.0 2.6 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EIM92731.1 - 0.0012 18.9 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 EIM92731.1 - 0.024 14.8 0.1 0.064 13.4 0.1 1.7 1 1 0 1 1 1 0 U-box domain zf-Nse PF11789.8 EIM92731.1 - 0.11 12.3 0.1 1.8 8.4 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PPR_2 PF13041.6 EIM92732.1 - 3.3e-37 126.5 0.1 4.7e-09 36.3 0.4 7.3 4 2 3 7 7 7 6 PPR repeat family PPR_3 PF13812.6 EIM92732.1 - 1.7e-21 76.1 0.0 2.4e-06 27.5 0.0 6.7 5 2 2 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 EIM92732.1 - 3.1e-19 67.8 8.1 1.2e-05 25.2 0.1 9.6 8 2 0 8 8 8 4 PPR repeat PPR_1 PF12854.7 EIM92732.1 - 1.2e-10 40.9 1.2 3.6 7.4 0.0 8.8 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 EIM92732.1 - 5.8e-08 32.4 0.2 0.012 15.0 0.0 3.7 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP HOASN PF14515.6 EIM92732.1 - 0.035 14.5 0.1 0.64 10.4 0.0 2.7 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices Sugar_tr PF00083.24 EIM92733.1 - 2.8e-106 356.1 12.2 3.2e-106 355.9 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM92733.1 - 7.1e-30 104.1 48.0 1.4e-24 86.7 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EIM92733.1 - 2.9e-07 29.4 9.2 0.00027 19.6 1.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF1156 PF06634.12 EIM92733.1 - 0.21 11.7 0.3 0.53 10.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) DEAD PF00270.29 EIM92734.1 - 1.1e-17 64.4 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM92734.1 - 2.7e-05 24.5 0.0 8.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIM92734.1 - 0.0098 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EIM92734.1 - 0.044 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EIM92734.1 - 0.065 12.3 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4203 PF13886.6 EIM92735.1 - 2.4e-52 177.5 28.0 2.4e-52 177.5 28.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) DUF812 PF05667.11 EIM92735.1 - 0.019 13.8 0.4 0.019 13.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF812) Mucin PF01456.17 EIM92735.1 - 3.2 7.7 22.9 0.68 9.9 18.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Prenyltransf PF01255.19 EIM92736.1 - 2e-76 256.4 0.0 2.4e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ras PF00071.22 EIM92737.1 - 8.9e-29 100.2 0.0 1.1e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM92737.1 - 5.5e-06 26.6 0.0 9.6e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EIM92737.1 - 0.00013 21.6 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EIM92737.1 - 0.0055 15.9 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit FeoB_N PF02421.18 EIM92737.1 - 0.14 11.7 0.0 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-RING_2 PF13639.6 EIM92738.1 - 9.6e-06 25.8 5.8 9.6e-06 25.8 5.8 2.1 2 1 0 2 2 1 1 Ring finger domain SWIM PF04434.17 EIM92738.1 - 1.8e-05 24.2 0.3 3.4e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.29 EIM92738.1 - 0.0052 16.6 6.6 0.0099 15.7 6.6 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EIM92738.1 - 0.0087 16.0 1.4 0.0087 16.0 1.4 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 EIM92738.1 - 0.044 13.3 1.3 0.089 12.4 1.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 EIM92738.1 - 0.053 13.1 2.8 0.096 12.3 2.8 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain FANCL_C PF11793.8 EIM92738.1 - 0.11 12.7 6.6 0.12 12.6 4.4 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 EIM92738.1 - 0.13 12.4 6.6 0.28 11.3 6.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 EIM92738.1 - 0.22 11.4 5.6 0.89 9.5 5.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIM92738.1 - 0.56 10.0 5.2 1.1 9.1 5.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EIM92738.1 - 3.8 7.2 8.5 0.92 9.2 4.6 2.0 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EIM92738.1 - 7.8 6.6 9.6 2.1 8.4 4.3 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger LAG1-DNAbind PF09271.11 EIM92740.1 - 2.6e-28 99.5 0.2 1.1e-16 61.8 0.2 2.3 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.10 EIM92740.1 - 6.5e-25 88.1 0.0 2.1e-24 86.5 0.0 1.9 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain PK PF00224.21 EIM92741.1 - 2.1e-164 546.5 0.8 2.6e-164 546.2 0.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EIM92741.1 - 2e-37 128.0 0.0 6.1e-37 126.4 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EIM92741.1 - 0.0001 21.5 0.6 0.0003 20.0 0.6 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EIM92741.1 - 0.01 14.8 0.1 0.079 11.9 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Gly_transf_sug PF04488.15 EIM92742.1 - 2.3e-05 24.9 0.0 5.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EIM92742.1 - 0.042 13.2 0.2 0.07 12.5 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribul_P_3_epim PF00834.19 EIM92743.1 - 1.1e-59 201.2 0.0 1.3e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 EIM92743.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain BRF1 PF07741.13 EIM92744.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain RINT1_TIP1 PF04437.13 EIM92745.1 - 9.5e-101 338.1 0.0 5.5e-100 335.6 0.0 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CENP-F_leu_zip PF10473.9 EIM92745.1 - 0.034 14.2 6.5 3.3 7.7 4.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERp29 PF07749.12 EIM92745.1 - 0.08 13.8 1.1 0.66 10.9 0.1 2.8 2 1 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain MFAP1 PF06991.11 EIM92746.1 - 1.4e-67 227.8 27.4 1.4e-67 227.8 27.4 1.7 2 0 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing NAD_binding_8 PF13450.6 EIM92746.1 - 1.8e-12 47.3 0.0 6.1e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIM92746.1 - 0.011 15.4 2.8 0.039 13.5 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIM92746.1 - 0.038 13.2 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain CHAT PF12770.7 EIM92747.1 - 0.00026 20.5 0.0 0.00047 19.6 0.0 1.4 1 1 0 1 1 1 1 CHAT domain CHAT PF12770.7 EIM92748.1 - 9.8e-15 54.7 0.0 2.6e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 CHAT domain Rhodanese PF00581.20 EIM92749.1 - 1.8e-14 54.2 0.0 3.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Ctr PF04145.15 EIM92750.1 - 7.9e-28 97.9 0.0 9.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ApeC PF16977.5 EIM92751.1 - 0.2 11.6 0.8 0.27 11.1 0.1 1.6 2 1 0 2 2 2 0 C-terminal domain of apextrin RAP1 PF07218.11 EIM92751.1 - 7.8 4.6 5.8 8.2 4.6 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF515 PF04415.12 EIM92751.1 - 9.5 4.5 5.7 11 4.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) XRCC4 PF06632.12 EIM92752.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF782 PF05614.11 EIM92752.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) OrfB_Zn_ribbon PF07282.11 EIM92753.1 - 0.035 14.0 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Rhodanese PF00581.20 EIM92754.1 - 6.8e-20 71.6 0.0 2.7e-11 43.9 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.15 EIM92755.1 - 6.3e-129 430.6 3.3 7.1e-129 430.4 3.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Gti1_Pac2 PF09729.9 EIM92756.1 - 9.9e-40 136.6 0.1 1.4e-32 113.3 0.0 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family KH_1 PF00013.29 EIM92757.1 - 1.2e-36 124.4 1.4 1.2e-08 34.7 0.0 7.6 7 1 0 7 7 7 5 KH domain zf-RING_2 PF13639.6 EIM92758.1 - 2.5e-06 27.7 9.2 4.7e-06 26.8 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EIM92758.1 - 6.1e-06 26.2 8.6 1.2e-05 25.2 8.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIM92758.1 - 0.00025 20.8 10.9 0.00049 19.9 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM92758.1 - 0.00034 20.4 8.6 0.00084 19.1 8.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM92758.1 - 0.0016 18.2 6.4 0.0033 17.1 6.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EIM92758.1 - 0.0061 16.5 10.7 0.014 15.3 10.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain RWD PF05773.22 EIM92758.1 - 0.0087 16.3 1.9 0.0088 16.3 0.3 1.8 1 1 0 2 2 2 1 RWD domain Baculo_IE-1 PF05290.11 EIM92758.1 - 0.064 13.2 2.4 0.11 12.5 2.4 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zn_ribbon_17 PF17120.5 EIM92758.1 - 0.12 12.0 7.5 0.2 11.3 7.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EIM92758.1 - 0.17 11.8 9.1 0.4 10.6 9.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EIM92758.1 - 0.44 10.7 10.5 4 7.7 10.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING IBR PF01485.21 EIM92758.1 - 5.1 7.4 12.2 2.6 8.3 7.4 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 EIM92758.1 - 7.2 6.6 9.0 1.8e+02 2.1 8.2 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein IBR PF01485.21 EIM92759.1 - 1.4e-18 66.8 40.8 8e-12 45.2 3.8 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EIM92759.1 - 1.5e-16 60.7 0.2 3.3e-16 59.6 0.2 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 EIM92759.1 - 5.5e-06 26.3 7.1 5.5e-06 26.3 7.1 3.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EIM92759.1 - 1.2e-05 25.5 10.0 1.2e-05 25.5 10.0 4.7 3 2 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 EIM92759.1 - 0.00032 20.5 5.4 0.00032 20.5 5.4 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIM92759.1 - 0.00079 19.2 8.3 0.00079 19.2 8.3 5.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM92759.1 - 0.0029 17.5 7.1 0.0029 17.5 7.1 4.6 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EIM92759.1 - 0.0082 16.3 6.0 0.0082 16.3 6.0 5.2 4 2 0 4 4 4 1 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 EIM92759.1 - 2.6 8.3 20.0 0.076 13.2 4.9 3.4 3 0 0 3 3 3 0 FYVE-type zinc finger Urb2 PF10441.9 EIM92760.1 - 4.5e-45 154.1 10.8 1.3e-43 149.3 0.0 4.4 4 0 0 4 4 4 2 Urb2/Npa2 family Beta_elim_lyase PF01212.21 EIM92761.1 - 5.4e-72 242.5 0.0 8.6e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EIM92761.1 - 0.012 14.1 0.0 0.042 12.4 0.0 1.6 1 1 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Nbs1_C PF08599.10 EIM92761.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 zf-met2 PF12907.7 EIM92762.1 - 6.2e-17 61.4 0.9 9.4e-17 60.9 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EIM92762.1 - 1.8e-05 25.5 13.8 1.8e-05 25.5 13.8 1.6 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_12 PF18658.1 EIM92762.1 - 0.062 12.9 0.3 0.086 12.4 0.3 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-Tim10_DDP PF02953.15 EIM92763.1 - 1.9e-20 72.2 0.6 2.3e-20 72.0 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ANAPC4_WD40 PF12894.7 EIM92764.1 - 1.4e-06 28.5 1.0 0.013 15.8 0.0 5.2 5 1 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIM92764.1 - 0.048 14.5 25.4 4.3 8.4 0.4 8.1 9 0 0 9 9 9 0 WD domain, G-beta repeat PD40 PF07676.12 EIM92764.1 - 0.08 12.9 0.1 11 6.1 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HemY_N PF07219.13 EIM92764.1 - 0.16 12.1 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus C2 PF00168.30 EIM92766.1 - 8.8e-85 279.7 4.5 3.4e-17 62.6 0.0 6.3 6 0 0 6 6 6 5 C2 domain NT-C2 PF10358.9 EIM92766.1 - 0.016 14.9 0.1 2.3 7.9 0.0 3.9 4 1 0 4 4 4 0 N-terminal C2 in EEIG1 and EHBP1 proteins NAD_binding_6 PF08030.12 EIM92768.1 - 9.3e-22 77.8 0.0 1.4e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EIM92768.1 - 6.4e-19 68.3 27.1 7e-19 68.2 15.8 2.8 2 1 0 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIM92768.1 - 4.8e-13 49.1 0.0 9.4e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 EIM92768.1 - 0.043 14.4 16.2 0.28 11.7 1.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Ground-like PF04155.18 EIM92768.1 - 0.17 12.6 0.0 0.4 11.4 0.0 1.6 1 0 0 1 1 1 0 Ground-like domain Oxidored_q3 PF00499.20 EIM92768.1 - 0.59 9.8 8.7 7.4 6.3 8.7 2.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ferric_reduct PF01794.19 EIM92769.1 - 2.7e-19 69.5 12.1 2.7e-19 69.5 12.1 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EIM92769.1 - 8.4e-18 65.0 0.0 2e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIM92769.1 - 3.2e-16 59.4 0.0 6.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EIM92769.1 - 0.0038 17.8 0.0 0.0071 17.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PTH2 PF01981.16 EIM92770.1 - 3.3e-36 124.1 0.1 3.6e-36 124.0 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2573 PF10835.8 EIM92770.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) SUR7 PF06687.12 EIM92771.1 - 0.0066 16.1 1.7 0.0066 16.1 1.7 3.0 3 1 1 4 4 4 1 SUR7/PalI family BNR PF02012.20 EIM92772.1 - 0.033 14.1 3.2 0.3 11.2 0.1 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat Peptidase_C48 PF02902.19 EIM92773.1 - 1.3e-38 133.0 1.6 4.5e-38 131.3 1.6 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Use1 PF09753.9 EIM92774.1 - 0.017 14.9 0.1 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Sec20 PF03908.13 EIM92774.1 - 0.056 13.4 0.1 0.13 12.2 0.0 1.5 1 1 0 2 2 2 0 Sec20 p450 PF00067.22 EIM92775.1 - 3.6e-51 174.4 0.0 4.1e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yippee-Mis18 PF03226.14 EIM92776.1 - 2.3e-18 66.3 0.4 2.6e-18 66.2 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EIM92776.1 - 0.018 15.2 0.7 0.025 14.8 0.7 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I adh_short_C2 PF13561.6 EIM92778.1 - 4.5e-59 199.8 0.0 5.5e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM92778.1 - 1.2e-45 155.4 0.2 1.4e-45 155.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM92778.1 - 1.1e-09 38.5 0.2 1.4e-09 38.2 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM92778.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EIM92778.1 - 0.0011 18.4 0.0 0.0076 15.7 0.0 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EIM92778.1 - 0.055 12.8 0.2 0.078 12.3 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ras PF00071.22 EIM92782.1 - 1.7e-47 161.1 0.1 2e-47 160.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIM92782.1 - 2.7e-16 59.9 0.1 6.4e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIM92782.1 - 0.00029 20.3 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIM92782.1 - 0.0004 20.0 0.0 0.003 17.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIM92782.1 - 0.00066 19.6 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EIM92782.1 - 0.018 14.6 0.2 1.4 8.4 0.0 3.1 1 1 2 3 3 3 0 Ferrous iron transport protein B AAA_25 PF13481.6 EIM92782.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tim17 PF02466.19 EIM92783.1 - 2.9e-13 50.2 0.4 5.6e-13 49.2 0.4 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Chromo PF00385.24 EIM92784.1 - 2.2e-11 43.5 0.4 4.5e-11 42.5 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 EIM92785.1 - 5.8e-56 188.6 0.0 9.3e-38 129.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIM92785.1 - 1.8e-11 44.5 0.1 0.00086 19.6 0.0 4.0 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EIM92785.1 - 9.7e-11 42.3 0.0 0.0012 19.3 0.1 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 EIM92785.1 - 1.5e-09 37.5 0.0 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 EIM92785.1 - 3.4e-09 36.3 0.4 2.7e-07 30.3 0.1 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 EIM92785.1 - 1.1e-08 35.2 0.0 0.0026 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EIM92785.1 - 1.2e-08 35.3 0.7 8.4e-05 22.7 0.2 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EIM92785.1 - 1.6e-08 34.5 0.1 0.0035 17.1 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EIM92785.1 - 1.9e-07 31.3 0.0 0.018 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EIM92785.1 - 2.8e-07 30.1 0.0 0.0069 15.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EIM92785.1 - 8e-07 28.6 0.7 0.013 14.9 0.2 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EIM92785.1 - 2.5e-06 28.0 0.0 0.1 13.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EIM92785.1 - 3.7e-06 26.8 0.0 0.037 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EIM92785.1 - 5e-06 26.4 0.0 0.12 12.2 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EIM92785.1 - 5.4e-06 26.4 0.2 0.095 12.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EIM92785.1 - 5.7e-06 26.2 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EIM92785.1 - 7.2e-06 26.4 0.0 0.18 12.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.26 EIM92785.1 - 8.7e-06 25.5 0.0 0.058 13.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_30 PF13604.6 EIM92785.1 - 1.2e-05 25.1 0.1 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EIM92785.1 - 2e-05 24.6 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EIM92785.1 - 2.6e-05 23.7 0.5 0.013 14.8 0.1 2.5 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 EIM92785.1 - 4.6e-05 23.0 1.4 0.059 12.9 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region NACHT PF05729.12 EIM92785.1 - 9.8e-05 22.3 0.4 0.48 10.3 0.0 3.1 3 0 0 3 3 3 2 NACHT domain AAA_14 PF13173.6 EIM92785.1 - 0.00013 22.0 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EIM92785.1 - 0.00016 20.8 0.0 0.079 12.0 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 EIM92785.1 - 0.00023 21.5 0.7 1.6 9.1 0.1 3.2 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 EIM92785.1 - 0.00044 20.3 0.0 0.41 10.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EIM92785.1 - 0.00092 18.5 0.3 1.5 8.0 0.2 2.5 2 0 0 2 2 2 2 NB-ARC domain Hydin_ADK PF17213.3 EIM92785.1 - 0.0012 19.2 0.2 0.29 11.4 0.1 2.3 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain PhoH PF02562.16 EIM92785.1 - 0.0013 18.2 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 EIM92785.1 - 0.0021 18.6 0.1 0.41 11.2 0.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 EIM92785.1 - 0.0024 17.5 2.1 2.4 7.7 0.2 3.4 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.6 EIM92785.1 - 0.0024 18.1 0.0 2.5 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 EIM92785.1 - 0.0031 17.6 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Torsin CDC48_N PF02359.18 EIM92785.1 - 0.0036 17.5 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain DUF2075 PF09848.9 EIM92785.1 - 0.01 15.1 0.8 3.8 6.7 0.1 2.7 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 EIM92785.1 - 0.013 15.4 0.1 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 EIM92785.1 - 0.015 14.4 0.1 2.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EIM92785.1 - 0.028 13.7 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 EIM92785.1 - 0.029 14.8 0.1 2 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EIM92785.1 - 0.046 13.2 0.0 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EIM92785.1 - 0.051 13.5 0.1 14 5.6 0.0 2.7 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 EIM92785.1 - 0.053 13.4 0.1 14 5.6 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain IPT PF01745.16 EIM92785.1 - 0.053 12.9 0.1 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase TniB PF05621.11 EIM92785.1 - 0.082 12.3 0.0 8.4 5.7 0.0 2.9 2 1 0 2 2 2 0 Bacterial TniB protein Zot PF05707.12 EIM92785.1 - 0.083 12.5 0.0 20 4.7 0.0 2.9 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 EIM92785.1 - 0.088 12.5 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Vps4_C PF09336.10 EIM92785.1 - 0.11 12.6 0.0 0.83 9.7 0.0 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.18 EIM92785.1 - 0.14 11.8 0.0 17 5.0 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 EIM92785.1 - 0.17 12.0 0.0 39 4.4 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain DAP3 PF10236.9 EIM92785.1 - 0.26 10.4 0.3 21 4.2 0.0 2.4 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 UPF0121 PF03661.13 EIM92786.1 - 2.8e-41 141.5 1.5 3.5e-41 141.2 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HAP PF03866.13 EIM92787.1 - 0.007 16.4 4.5 0.0088 16.1 4.5 1.0 1 0 0 1 1 1 1 Hydrophobic abundant protein (HAP) FixQ PF05545.11 EIM92787.1 - 1.2 9.1 4.5 0.62 10.1 1.9 1.9 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CBS PF00571.28 EIM92788.1 - 4.1e-31 107.2 5.8 3.7e-09 36.9 0.1 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 EIM92788.1 - 8.6e-06 25.6 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 PB1 domain AbiEi_4 PF13338.6 EIM92788.1 - 0.18 12.0 0.1 7.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Glyco_hydro_79C PF16862.5 EIM92789.1 - 5.1e-11 43.4 0.1 1.3e-10 42.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Frataxin_Cyay PF01491.16 EIM92790.1 - 3.8e-40 136.3 0.1 5.7e-40 135.8 0.1 1.3 1 0 0 1 1 1 1 Frataxin-like domain PRIMA1 PF16101.5 EIM92791.1 - 0.56 10.3 7.4 5 7.2 0.4 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 WD40 PF00400.32 EIM92792.1 - 6.6e-18 64.8 12.3 0.00028 21.6 0.3 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92792.1 - 5.4e-07 29.8 0.1 1.4 9.3 0.0 5.3 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIM92792.1 - 4.6e-05 23.4 0.0 0.089 12.7 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EIM92792.1 - 0.00027 20.0 0.1 0.0027 16.7 0.0 2.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EIM92792.1 - 0.057 12.0 0.0 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Bromodomain PF00439.25 EIM92793.1 - 1.4e-36 124.4 0.0 4.3e-20 71.6 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EIM92793.1 - 1.3e-18 66.9 1.0 3.3e-18 65.6 1.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Hid1 PF12722.7 EIM92793.1 - 0.065 11.4 5.3 0.12 10.5 5.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 EIM92793.1 - 0.18 10.3 5.6 0.28 9.7 5.6 1.3 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 EIM92793.1 - 0.29 8.9 2.6 0.42 8.3 2.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 EIM92793.1 - 0.74 6.9 2.3 1.2 6.2 2.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM214 PF10151.9 EIM92793.1 - 2.7 6.4 6.4 4.1 5.8 6.4 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF3138 PF11336.8 EIM92793.1 - 3.3 6.2 8.1 1.8 7.1 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) G-patch PF01585.23 EIM92794.1 - 3.6e-09 36.4 0.0 7.3e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 EIM92794.1 - 3.6e-06 27.1 5.3 5.7e-06 26.5 5.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIM92794.1 - 4.3e-05 23.8 1.8 7.1e-05 23.1 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 EIM92794.1 - 0.00013 22.0 0.1 0.00013 22.0 0.1 2.8 3 0 0 3 3 3 1 G-patch domain zf-C2H2_2 PF12756.7 EIM92794.1 - 0.0048 17.2 0.6 0.0081 16.5 0.6 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 EIM92794.1 - 0.08 13.1 0.4 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger zf-DBF PF07535.12 EIM92794.1 - 0.49 10.6 2.3 0.82 9.8 2.3 1.3 1 0 0 1 1 1 0 DBF zinc finger DUF4820 PF16091.5 EIM92794.1 - 1.5 8.1 9.9 2.9 7.2 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PWI PF01480.17 EIM92795.1 - 7.6e-10 39.0 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 EIM92795.1 - 3.5e-06 26.8 5.2 6.6e-06 25.9 5.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIM92795.1 - 0.00024 21.0 7.5 0.00044 20.2 7.5 1.5 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 EIM92795.1 - 0.0044 16.8 0.1 0.045 13.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIM92795.1 - 0.0073 16.3 0.1 0.022 14.8 0.1 1.8 1 0 0 1 1 1 1 RNA binding motif DUF4407 PF14362.6 EIM92795.1 - 0.0075 15.7 3.0 0.012 14.9 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EIM92795.1 - 0.092 12.3 0.6 0.15 11.6 0.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MerR-DNA-bind PF09278.11 EIM92795.1 - 0.86 10.2 3.6 0.56 10.8 0.5 2.2 2 0 0 2 2 2 0 MerR, DNA binding Abhydrolase_1 PF00561.20 EIM92796.1 - 1.9e-19 70.3 0.1 7.1e-19 68.5 0.0 1.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EIM92796.1 - 3.3e-19 68.9 0.0 5.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FANCI_HD2 PF14680.6 EIM92797.1 - 0.006 15.9 0.1 0.0071 15.6 0.1 1.0 1 0 0 1 1 1 1 FANCI helical domain 2 COG2 PF06148.11 EIM92797.1 - 0.48 10.5 2.7 7.1 6.7 0.0 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SEEK1 PF15357.6 EIM92797.1 - 1.2 9.2 6.3 1.8 8.7 6.3 1.2 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Abhydrolase_1 PF00561.20 EIM92798.1 - 1.9e-13 50.7 0.3 3.9e-13 49.6 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EIM92798.1 - 5.6e-07 29.6 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein NUDIX PF00293.28 EIM92799.1 - 1.8e-08 34.5 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain EptA_B_N PF08019.12 EIM92800.1 - 0.058 13.3 0.1 0.058 13.3 0.1 3.4 5 0 0 5 5 5 0 Phosphoethanolamine transferase EptA/EptB PIG-F PF06699.11 EIM92800.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.5 3 0 0 3 3 3 0 GPI biosynthesis protein family Pig-F DDDD PF10161.9 EIM92800.1 - 0.14 11.9 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Putative mitochondrial precursor protein CrgA PF06781.12 EIM92800.1 - 1.6 8.9 0.0 1.6 8.9 0.0 2.9 4 0 0 4 4 4 0 Cell division protein CrgA NPL4 PF05021.15 EIM92801.1 - 7.3e-102 340.8 0.0 9.6e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EIM92801.1 - 4.5e-64 215.0 0.0 6.9e-64 214.4 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EIM92801.1 - 3.7e-05 24.1 0.0 7.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.15 EIM92802.1 - 4e-12 46.0 14.3 2.1e-11 43.7 9.4 1.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EIM92802.1 - 8.2e-07 29.0 7.4 3.4e-06 27.1 7.4 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EIM92802.1 - 7.2e-05 23.2 3.5 7.5e-05 23.2 3.5 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor Shugoshin_N PF07558.11 EIM92802.1 - 0.0011 18.8 0.1 0.002 18.0 0.1 1.6 1 1 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF2205 PF10224.9 EIM92802.1 - 0.0049 16.8 0.9 0.0051 16.8 0.9 1.1 1 0 0 1 1 1 1 Short coiled-coil protein TSC22 PF01166.18 EIM92802.1 - 0.015 15.6 0.2 0.024 14.9 0.2 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 EIM92802.1 - 0.018 14.8 1.1 0.02 14.6 1.0 1.2 1 1 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 EIM92802.1 - 0.025 15.0 0.5 0.036 14.5 0.3 1.4 1 1 0 1 1 1 0 Cell division protein ZapB DUF1151 PF06625.11 EIM92802.1 - 0.067 13.1 2.8 0.066 13.2 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) NRBF2 PF08961.10 EIM92802.1 - 0.077 12.6 1.8 0.09 12.4 1.8 1.0 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Imm7 PF15585.6 EIM92802.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 7 HSBP1 PF06825.12 EIM92802.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.4 1 1 0 1 1 1 0 Heat shock factor binding protein 1 CHCH PF06747.13 EIM92803.1 - 1.7e-07 31.2 10.0 7.4e-05 22.8 2.4 2.2 1 1 1 2 2 2 2 CHCH domain NDUF_B7 PF05676.13 EIM92803.1 - 0.00035 20.2 1.9 0.00045 19.9 1.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 EIM92803.1 - 0.002 18.4 4.3 0.0054 17.0 4.6 1.5 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EIM92803.1 - 0.0072 16.3 1.3 0.011 15.7 1.3 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sld5 PF05916.11 EIM92803.1 - 0.12 12.9 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 GINS complex protein Glyco_hydro_79C PF16862.5 EIM92807.1 - 4.4e-09 37.2 0.0 1e-08 36.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain GluR_Homer-bdg PF10606.9 EIM92807.1 - 0.11 12.7 0.5 4.8 7.5 0.0 3.1 2 1 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor DinB_2 PF12867.7 EIM92808.1 - 1.7e-08 35.0 0.1 2.1e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 EIM92808.1 - 0.00056 19.9 0.1 0.00072 19.5 0.1 1.1 1 0 0 1 1 1 1 DinB family EpmC PF04315.12 EIM92808.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P hydroxylase ATP-grasp_2 PF08442.10 EIM92809.1 - 4e-67 225.7 1.4 6e-67 225.1 0.5 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EIM92809.1 - 1.9e-26 92.7 0.1 3.9e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EIM92809.1 - 1.5e-07 31.1 1.1 4.7e-06 26.2 0.4 2.8 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EIM92809.1 - 0.0009 19.1 0.3 0.0031 17.3 0.3 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Tfb4 PF03850.14 EIM92810.1 - 0.074 12.5 1.9 0.12 11.8 1.9 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Zip PF02535.22 EIM92810.1 - 0.83 8.8 2.7 0.96 8.6 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MMR1 PF08505.10 EIM92810.1 - 7.5 6.8 17.1 2 8.6 10.9 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.16 EIM92810.1 - 7.6 6.5 9.9 0.96 9.5 5.1 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BCAS2 PF05700.11 EIM92812.1 - 1.9e-54 184.5 9.7 2.1e-54 184.3 9.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 EIM92812.1 - 2.5e-06 27.5 0.1 3.9e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Baculo_PEP_C PF04513.12 EIM92812.1 - 0.017 15.2 0.8 0.028 14.5 0.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_MA_2 PF13485.6 EIM92812.1 - 0.044 13.5 0.1 0.13 11.9 0.0 1.6 1 1 1 2 2 2 0 Peptidase MA superfamily Complex1_30kDa PF00329.19 EIM92813.1 - 9.4e-45 152.2 0.0 1.3e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF5427 PF10310.9 EIM92814.1 - 2.1e-60 205.0 3.4 5.9e-56 190.4 0.0 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5427) DUF1726 PF08351.11 EIM92814.1 - 0.038 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Abhydrolase_1 PF00561.20 EIM92815.1 - 8e-12 45.3 0.1 1.6e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EIM92815.1 - 1.6e-06 28.2 0.0 3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Mito_carr PF00153.27 EIM92816.1 - 2.1e-20 72.4 0.0 3.8e-07 29.9 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein Aminotran_1_2 PF00155.21 EIM92817.1 - 4.5e-14 52.4 0.0 9.4e-12 44.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Endotoxin_M PF00555.19 EIM92817.1 - 0.047 13.7 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 delta endotoxin Metallophos PF00149.28 EIM92818.1 - 4.6e-14 53.4 0.0 8.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIM92818.1 - 0.0016 18.7 0.1 0.0092 16.2 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 EIM92819.1 - 6.6e-08 32.3 0.0 3.1e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EIM92819.1 - 0.0055 16.6 3.3 1 9.3 0.0 3.0 3 0 0 3 3 3 2 F-box domain His_Phos_1 PF00300.22 EIM92820.1 - 4.3e-14 52.7 1.1 9.4e-14 51.5 1.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.12 EIM92821.1 - 5.5e-31 106.7 2.4 1.1e-30 105.7 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIM92821.1 - 1.2e-16 60.9 0.2 2.4e-16 59.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIM92821.1 - 1.1e-07 31.6 0.1 7.4e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIM92821.1 - 2.5e-06 28.6 0.0 5.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EIM92821.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EIM92821.1 - 0.075 13.7 0.0 0.15 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PIN PF01850.21 EIM92821.1 - 0.14 12.6 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 PIN domain RNase_T PF00929.24 EIM92822.1 - 2.5e-11 44.4 0.0 4.8e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 EIM92822.1 - 0.25 11.3 0.0 15 5.6 0.0 2.2 2 0 0 2 2 2 0 RNase_H superfamily MFS_1 PF07690.16 EIM92823.1 - 1.3e-22 80.2 73.0 1.1e-21 77.2 46.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTH2 PF01981.16 EIM92824.1 - 2.2e-33 115.0 0.0 2.5e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RNase_T PF00929.24 EIM92825.1 - 2.6e-11 44.4 0.0 6.3e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Exonuclease RNase_T PF00929.24 EIM92826.1 - 3.2e-05 24.5 0.0 0.00014 22.5 0.0 1.8 2 0 0 2 2 2 1 Exonuclease DUF5051 PF16473.5 EIM92826.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like GMC_oxred_C PF05199.13 EIM92826.1 - 0.12 12.8 0.2 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pkinase PF00069.25 EIM92827.1 - 1.3e-47 162.4 0.0 3.6e-47 161.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92827.1 - 1.8e-33 115.9 0.0 4.8e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM92827.1 - 3.9e-05 22.6 0.2 0.00011 21.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase SOG2 PF10428.9 EIM92827.1 - 0.068 12.4 15.5 0.11 11.7 15.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 EIM92827.1 - 8 5.2 7.0 12 4.6 7.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 EIM92828.1 - 1e-44 152.9 0.0 2.2e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92828.1 - 3.2e-11 43.0 0.0 4.2e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIM92828.1 - 0.0036 16.1 1.2 0.043 12.6 0.1 2.1 1 1 1 2 2 2 1 Fungal protein kinase Sgf11 PF08209.11 EIM92829.1 - 2.3e-11 43.1 0.6 4.5e-11 42.1 0.6 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) EF-hand_1 PF00036.32 EIM92830.1 - 8.7e-38 125.1 5.1 2.4e-09 36.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EIM92830.1 - 8.1e-31 106.3 1.1 1.3e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EIM92830.1 - 3.5e-28 95.1 2.3 1.4e-08 34.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EIM92830.1 - 9.4e-27 92.6 8.0 3.1e-11 42.9 0.2 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EIM92830.1 - 3.8e-26 89.4 5.1 1.5e-07 30.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EIM92830.1 - 1.2e-13 51.2 0.1 4.7e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EIM92830.1 - 5.1e-05 23.6 0.0 0.26 11.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EIM92830.1 - 0.00012 22.0 0.1 0.74 9.7 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein UPF0154 PF03672.13 EIM92830.1 - 0.00015 21.7 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 EIM92830.1 - 0.00016 21.9 0.1 0.65 10.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EIM92830.1 - 0.00024 21.0 0.8 0.64 10.0 0.1 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 EIM92830.1 - 0.0014 18.6 0.1 1.2 9.0 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_11 PF08976.11 EIM92830.1 - 0.0015 19.4 0.0 0.91 10.4 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 EIM92830.1 - 0.0036 17.5 5.4 0.94 9.7 0.4 2.9 1 1 2 3 3 3 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 EIM92830.1 - 0.031 14.6 0.3 0.78 10.1 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb4 SurA_N_2 PF13623.6 EIM92830.1 - 0.034 14.0 0.6 2.4 8.0 0.4 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF1296 PF06972.11 EIM92830.1 - 0.056 13.6 0.1 6.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF1103 PF06513.11 EIM92830.1 - 0.064 12.9 0.6 0.081 12.5 0.6 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) FGAR-AT_linker PF18072.1 EIM92830.1 - 0.07 13.7 0.0 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DEAD PF00270.29 EIM92831.1 - 2.2e-46 157.8 0.0 3.5e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIM92831.1 - 2.8e-24 85.6 0.0 1.6e-23 83.2 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EIM92831.1 - 7.6e-18 64.5 0.2 1.5e-17 63.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EIM92831.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIM92831.1 - 0.14 12.4 0.2 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EIM92832.1 - 2.5e-07 31.3 14.6 1.2e-06 29.1 0.9 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92832.1 - 0.0022 18.3 0.1 0.53 10.6 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_79C PF16862.5 EIM92835.1 - 1.4e-07 32.3 0.2 5.3e-07 30.5 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain RRM_1 PF00076.22 EIM92837.1 - 1.3e-16 60.1 0.0 1.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EIM92837.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain RRM_5 PF13893.6 EIM92837.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.19 EIM92838.1 - 7.6e-60 202.1 49.5 4e-59 199.7 49.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIM92838.1 - 2.3e-23 82.7 0.1 1.9e-22 79.8 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EIM92838.1 - 5.3e-11 42.9 13.3 5.9e-06 26.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIM92838.1 - 1.4e-06 28.3 0.2 1.4e-06 28.3 0.2 4.2 2 2 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 EIM92838.1 - 6e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EIM92838.1 - 0.31 11.6 0.0 0.31 11.6 0.0 6.1 4 2 0 4 4 4 0 ABC transporter Pkinase PF00069.25 EIM92839.1 - 1.9e-37 129.1 0.0 1e-36 126.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92839.1 - 2.9e-20 72.6 0.0 4.5e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIM92839.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EIM92839.1 - 0.035 13.1 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EIM92839.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EIM92839.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EIM92839.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMP_PDE_delta PF05351.11 EIM92839.1 - 0.22 11.6 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 GMP-PDE, delta subunit Ank_5 PF13857.6 EIM92840.1 - 2.3e-16 59.6 0.3 4e-07 30.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIM92840.1 - 5.5e-13 49.2 0.0 2.5e-07 31.1 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIM92840.1 - 8.6e-12 45.5 0.4 2.4e-11 44.1 0.3 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIM92840.1 - 1.6e-10 41.0 0.0 0.00083 19.7 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EIM92840.1 - 3.9e-10 39.1 0.1 0.00016 21.8 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Aldo_ket_red PF00248.21 EIM92841.1 - 2.2e-48 165.0 0.0 2.7e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 EIM92842.1 - 2.2e-72 244.3 30.6 2.6e-72 244.1 30.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIM92842.1 - 7.8e-17 61.2 27.0 7.8e-17 61.2 27.0 2.7 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 EIM92842.1 - 5.5e-06 25.1 3.1 5.5e-06 25.1 3.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YrvL PF14184.6 EIM92842.1 - 0.015 15.4 5.3 0.015 15.4 5.3 2.7 3 0 0 3 3 3 0 Regulatory protein YrvL BatA PF07584.11 EIM92842.1 - 0.046 14.1 1.6 1.6 9.1 0.0 3.5 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Oxidored_q2 PF00420.24 EIM92843.1 - 7.8 6.2 8.7 0.82 9.3 3.5 2.0 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4527 PF15030.6 EIM92844.1 - 9.1 5.6 8.5 0.91 8.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) DUF1115 PF06544.12 EIM92845.1 - 1.1e-05 25.5 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Tannase PF07519.11 EIM92845.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase DUF726 PF05277.12 EIM92847.1 - 2.3e-121 404.9 0.5 3.3e-121 404.4 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 EIM92847.1 - 0.006 16.3 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3541 PF12060.8 EIM92847.1 - 0.11 12.2 0.6 0.19 11.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) LRR_4 PF12799.7 EIM92848.1 - 0.24 11.9 2.3 23 5.6 0.0 3.7 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) HTH_28 PF13518.6 EIM92850.1 - 0.0031 17.6 0.6 0.085 13.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EIM92850.1 - 0.0096 15.7 1.4 0.034 14.0 0.6 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EIM92850.1 - 0.043 13.8 0.1 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix CENP-B_N PF04218.13 EIM92850.1 - 0.053 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain SAM_2 PF07647.17 EIM92850.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mor PF08765.11 EIM92850.1 - 0.17 11.9 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Mor transcription activator family TfoX_C PF04994.13 EIM92850.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.5 1 1 0 1 1 1 0 TfoX C-terminal domain DUF2129 PF09902.9 EIM92851.1 - 0.1 12.7 0.1 0.43 10.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) DUF2110 PF09883.9 EIM92852.1 - 0.073 12.7 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Abhydrolase_3 PF07859.13 EIM92853.1 - 7.8e-48 163.1 0.0 1.2e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIM92853.1 - 2e-12 46.7 0.0 7.3e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EIM92853.1 - 0.00043 20.9 3.2 0.00072 20.2 3.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Serglycin PF04360.12 EIM92853.1 - 0.23 11.4 1.1 0.44 10.5 1.1 1.4 1 0 0 1 1 1 0 Serglycin Peptidase_M24 PF00557.24 EIM92854.1 - 1.2e-43 149.2 0.1 1.6e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 MLD PF11647.8 EIM92854.1 - 0.0043 17.3 0.1 0.013 15.7 0.1 1.8 1 0 0 1 1 1 1 Membrane Localization Domain YL1 PF05764.13 EIM92854.1 - 0.0075 16.4 7.0 0.011 15.9 7.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein TFIIF_alpha PF05793.12 EIM92854.1 - 0.43 9.1 11.5 0.65 8.5 11.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.12 EIM92854.1 - 1.2 9.1 8.5 0.13 12.2 2.7 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 GEN1_C PF18380.1 EIM92854.1 - 2.3 9.2 7.5 2.9 8.8 6.9 1.5 1 1 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain CDC45 PF02724.14 EIM92854.1 - 2.8 6.1 5.9 4 5.6 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.14 EIM92854.1 - 4.6 5.8 9.3 7.5 5.1 9.3 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 CAP PF00188.26 EIM92855.1 - 4.2e-22 79.3 2.3 6.1e-22 78.8 2.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 EIM92857.1 - 1.4e-21 77.6 0.9 4.8e-21 75.9 0.3 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP_N PF01213.19 EIM92857.1 - 0.11 11.9 10.7 0.17 11.4 10.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EIM92857.1 - 0.18 11.8 4.9 0.25 11.4 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 EIM92857.1 - 0.49 10.4 7.5 0.86 9.7 7.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 EIM92857.1 - 2.4 7.7 4.7 1.3 8.6 2.6 1.6 2 0 0 2 2 2 0 Virilizer, N-terminal DUF659 PF04937.15 EIM92858.1 - 2.3e-13 50.3 0.0 4.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Fumerase PF05681.14 EIM92858.1 - 0.089 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Glyco_hydro_28 PF00295.17 EIM92860.1 - 1.6e-36 126.0 4.3 2.3e-36 125.5 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Patatin PF01734.22 EIM92861.1 - 1.6e-05 25.2 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase REV1_C PF16727.5 EIM92863.1 - 0.027 14.9 3.1 2.6 8.5 0.2 3.2 3 1 0 3 3 3 0 DNA repair protein REV1 C-terminal domain DUF4360 PF14273.6 EIM92863.1 - 0.097 12.5 0.5 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) REF PF05755.12 EIM92863.1 - 5.5 6.8 10.1 2.5 7.9 0.2 3.7 3 1 1 4 4 4 0 Rubber elongation factor protein (REF) Flavin_Reduct PF01613.18 EIM92864.1 - 3e-12 46.9 0.0 3.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EIM92864.1 - 0.0003 20.6 0.1 0.00056 19.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 EIM92864.1 - 0.011 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ada_Zn_binding PF02805.16 EIM92865.1 - 4.8e-26 90.6 2.3 7.7e-26 89.9 2.3 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 EIM92865.1 - 0.00037 20.7 0.0 0.00066 19.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EIM92865.1 - 0.0021 18.1 0.0 0.0066 16.5 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Glyco_transf_22 PF03901.17 EIM92867.1 - 8.1e-90 302.0 16.0 1.2e-89 301.5 16.0 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EIM92867.1 - 0.002 18.3 8.2 0.002 18.3 8.2 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Forkhead PF00250.18 EIM92868.1 - 7e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain MRP-L28 PF09812.9 EIM92868.1 - 0.024 14.8 2.0 0.057 13.5 2.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF4200 PF13863.6 EIM92868.1 - 1.1 9.7 9.8 2 8.8 8.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) WD40 PF00400.32 EIM92869.1 - 9.6e-62 203.5 25.0 1.4e-06 28.9 0.3 12.2 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 EIM92869.1 - 4e-47 159.7 0.0 6.2e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EIM92869.1 - 9.4e-10 38.7 0.4 0.36 11.2 0.0 6.6 5 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIM92869.1 - 2.8e-06 26.3 9.4 0.068 11.8 1.3 5.6 4 2 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EIM92869.1 - 4.5e-05 22.6 1.8 1.4 7.9 0.1 5.2 4 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EIM92869.1 - 0.0024 16.7 6.1 14 4.3 0.0 5.6 3 2 2 6 6 6 3 Nup133 N terminal like Mcl1_mid PF12341.8 EIM92869.1 - 0.0058 16.0 0.0 1.4 8.2 0.0 2.7 3 0 0 3 3 3 2 Minichromosome loss protein, Mcl1, middle region Cytochrom_D1 PF02239.16 EIM92869.1 - 0.027 13.0 0.0 0.31 9.5 0.0 2.6 3 0 0 3 3 3 0 Cytochrome D1 heme domain BBS2_Mid PF14783.6 EIM92869.1 - 0.046 13.8 0.1 22 5.1 0.0 5.2 7 0 0 7 7 7 0 Ciliary BBSome complex subunit 2, middle region zf-C2H2 PF00096.26 EIM92870.1 - 1.8e-12 46.9 10.1 2.2e-06 27.8 1.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIM92870.1 - 1.5e-08 34.7 2.9 1.5e-08 34.7 2.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIM92870.1 - 2.9e-07 30.8 9.4 0.0021 18.8 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EIM92870.1 - 0.0011 19.5 2.5 0.56 10.9 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EIM92870.1 - 0.0055 16.7 0.2 0.0055 16.7 0.2 3.0 2 2 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIM92870.1 - 0.04 14.2 5.4 1.2 9.6 0.2 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-RAG1 PF10426.9 EIM92870.1 - 0.049 13.8 0.3 0.049 13.8 0.3 2.6 2 1 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_11 PF16622.5 EIM92870.1 - 0.065 13.0 2.1 0.065 13.0 2.1 2.3 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 EIM92870.1 - 0.13 12.4 7.0 44 4.2 2.8 1.9 1 1 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 EIM92870.1 - 0.19 11.5 14.2 0.61 9.9 1.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain N_BRCA1_IG PF16158.5 EIM92871.1 - 1.7e-31 108.9 0.1 3.7e-31 107.9 0.1 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EIM92871.1 - 1.9e-27 94.8 32.3 8.8e-10 38.2 4.3 3.3 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 EIM92871.1 - 1.3e-05 25.4 26.5 0.0067 16.7 1.8 3.5 3 0 0 3 3 3 3 C1 domain Aminotran_4 PF01063.19 EIM92872.1 - 3.1e-13 50.1 0.0 9.3e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV S4_2 PF13275.6 EIM92872.1 - 0.018 14.8 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 S4 domain ABM PF03992.16 EIM92873.1 - 2.5e-06 27.5 0.1 3.8e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Sirohm_synth_C PF14823.6 EIM92873.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal SRP14 PF02290.15 EIM92874.1 - 4.9e-22 78.1 2.2 1.5e-21 76.6 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle 14kD protein Tti2 PF10521.9 EIM92874.1 - 0.024 14.2 0.7 0.031 13.8 0.7 1.2 1 0 0 1 1 1 0 Tti2 family gag_pre-integrs PF13976.6 EIM92874.1 - 0.063 13.1 0.6 0.1 12.4 0.6 1.6 1 1 0 1 1 1 0 GAG-pre-integrase domain Polyhedrin PF00738.18 EIM92874.1 - 0.064 12.6 0.8 0.14 11.4 0.7 1.6 2 0 0 2 2 2 0 Polyhedrin AAA_26 PF13500.6 EIM92874.1 - 0.07 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.14 EIM92874.1 - 2.5 7.2 10.1 2.9 7.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TP_methylase PF00590.20 EIM92875.1 - 5.4e-42 144.1 0.3 1.2e-41 143.1 0.3 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EIM92875.1 - 4.2e-10 40.0 0.3 0.00043 20.7 0.0 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EIM92875.1 - 1.7e-08 33.7 0.1 4e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EIM92875.1 - 3.4e-08 33.0 3.8 7e-07 28.8 2.1 2.4 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Toxin_10 PF05431.11 EIM92875.1 - 0.061 12.8 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 COX5A PF02284.16 EIM92876.1 - 1.2e-43 147.4 0.4 1.5e-43 147.0 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF790 PF05626.11 EIM92876.1 - 0.053 12.2 0.3 0.055 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Homeodomain PF00046.29 EIM92877.1 - 3.9e-16 58.6 7.5 8.7e-16 57.5 7.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EIM92877.1 - 0.0017 18.2 0.1 0.0047 16.8 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain NESP55 PF06390.12 EIM92878.1 - 0.0094 15.6 2.2 0.01 15.5 2.2 1.1 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Phage_TAC_12 PF12363.8 EIM92878.1 - 0.035 14.5 0.1 0.55 10.7 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Bromodomain PF00439.25 EIM92881.1 - 9.3e-34 115.4 1.9 4.7e-16 58.6 0.3 2.5 2 0 0 2 2 2 2 Bromodomain DUF4777 PF16007.5 EIM92881.1 - 0.0083 16.4 0.0 6.6 7.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4777) F-box-like PF12937.7 EIM92882.1 - 8.1e-10 38.4 0.0 2.4e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like FA_desaturase PF00487.24 EIM92883.1 - 1.7e-16 60.8 19.4 1.7e-16 60.8 19.4 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIM92883.1 - 2.1e-05 24.6 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CutC PF03932.14 EIM92884.1 - 4.4e-35 121.0 0.0 6.3e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 CutC family Nramp PF01566.18 EIM92885.1 - 9.3e-89 297.9 15.8 2.6e-46 158.2 4.9 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein CCDC74_C PF14917.6 EIM92886.1 - 0.055 14.0 0.4 1.5 9.4 0.2 2.5 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal DUF815 PF05673.13 EIM92886.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Myosin_head PF00063.21 EIM92887.1 - 2.5e-239 796.0 0.1 3e-239 795.8 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EIM92887.1 - 8.9e-52 175.5 0.0 1.8e-51 174.5 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 EIM92887.1 - 1.5e-09 37.5 0.1 3.7e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIM92887.1 - 1.8e-08 33.8 0.9 3.5e-08 32.9 0.9 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EIM92887.1 - 2.7e-08 33.4 0.0 7.2e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EIM92887.1 - 2.4e-05 24.5 0.5 6.4e-05 23.1 0.5 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 EIM92887.1 - 0.0031 17.3 0.2 0.01 15.7 0.2 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain YopX PF09643.10 EIM92887.1 - 0.016 15.3 0.2 2.8 8.0 0.0 3.1 3 0 0 3 3 3 0 YopX protein AAA_22 PF13401.6 EIM92887.1 - 0.052 13.8 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EIM92887.1 - 0.076 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EIM92887.1 - 0.16 11.5 0.6 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 EIM92887.1 - 0.21 11.5 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UNC45-central PF11701.8 EIM92888.1 - 5.2e-36 123.9 0.0 1.9e-35 122.0 0.0 2.0 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Cnd3 PF12719.7 EIM92888.1 - 0.043 13.0 0.2 0.31 10.2 0.0 2.5 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EIM92888.1 - 0.5 10.8 14.5 0.33 11.4 0.2 5.5 4 3 2 6 6 6 0 HEAT repeats Arm PF00514.23 EIM92888.1 - 2.7 8.2 9.8 36 4.6 0.0 6.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Gcd10p PF04189.13 EIM92889.1 - 2.6e-68 230.4 0.0 3.8e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family Co_AT_N PF12557.8 EIM92889.1 - 0.006 16.5 0.3 0.015 15.2 0.3 1.7 1 0 0 1 1 1 1 Cob(I)alamin adenosyltransferase N terminal PXA PF02194.15 EIM92890.1 - 9e-47 159.4 0.2 1e-45 156.0 0.0 2.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EIM92890.1 - 8.9e-31 106.8 0.2 3.3e-30 104.9 0.2 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EIM92890.1 - 8.2e-17 61.2 0.2 6.6e-16 58.3 0.0 2.7 4 0 0 4 4 4 1 PX domain RGS PF00615.19 EIM92890.1 - 2.4e-10 40.7 0.1 8e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain ABC_tran_CTD PF16326.5 EIM92890.1 - 0.1 12.9 1.0 0.47 10.7 1.0 2.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF5394 PF17372.2 EIM92890.1 - 0.18 11.3 2.0 1.5 8.3 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5394) Mito_carr PF00153.27 EIM92891.1 - 2.4e-50 168.4 0.7 2e-17 62.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldedh PF00171.22 EIM92892.1 - 8.7e-126 420.1 0.0 1.1e-125 419.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuclease_T2 PF00445.18 EIM92893.1 - 4.6e-39 134.5 1.0 7.6e-39 133.8 1.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family ACT_7 PF13840.6 EIM92894.1 - 1.4e-18 66.4 0.0 2e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 ACT domain Castor1_N PF18700.1 EIM92894.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain zf-RING_2 PF13639.6 EIM92895.1 - 1.5e-10 41.3 6.4 1.5e-10 41.3 6.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EIM92895.1 - 7.3e-10 39.0 5.5 7.3e-10 39.0 5.5 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EIM92895.1 - 5.8e-07 29.4 3.8 5.8e-07 29.4 3.8 2.1 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIM92895.1 - 1.8e-06 27.7 8.1 1.8e-06 27.7 8.1 2.4 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIM92895.1 - 2.4e-06 27.4 4.8 2.4e-06 27.4 4.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EIM92895.1 - 4.9e-06 26.3 5.5 4.9e-06 26.3 5.5 2.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIM92895.1 - 1.3e-05 25.1 0.7 2.6e-05 24.2 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 EIM92895.1 - 3.8e-05 23.8 2.3 3.8e-05 23.8 2.3 2.9 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_3 PF13920.6 EIM92895.1 - 0.00012 21.9 3.5 0.00012 21.9 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIM92895.1 - 0.00077 19.2 5.6 0.00077 19.2 5.6 2.2 2 1 0 2 2 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 EIM92895.1 - 0.0012 18.7 7.0 0.0028 17.5 7.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EIM92895.1 - 0.024 14.8 3.5 0.094 12.9 3.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain HypA PF01155.19 EIM92895.1 - 0.037 14.1 4.5 0.71 9.9 0.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CSL PF05207.13 EIM92895.1 - 0.14 11.9 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 CSL zinc finger DUF1269 PF06897.12 EIM92895.1 - 0.15 12.4 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1269) DZR PF12773.7 EIM92895.1 - 0.47 10.5 8.3 8.5 6.5 0.8 3.1 3 0 0 3 3 3 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EIM92895.1 - 2.2 8.3 4.0 3 7.8 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PHD PF00628.29 EIM92895.1 - 8.4 6.4 17.3 0.34 10.8 5.4 2.7 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 EIM92895.1 - 9.3 6.2 8.3 12 5.8 0.3 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 EIM92895.1 - 9.9 6.2 9.6 3.7 7.6 0.5 2.8 2 1 1 3 3 3 0 zinc-ribbons Asp PF00026.23 EIM92896.1 - 2.7e-45 155.2 10.1 9.6e-45 153.3 10.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM92896.1 - 9.8e-08 32.4 7.4 3.6e-05 24.1 0.3 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM92896.1 - 0.0034 18.0 7.0 0.17 12.5 1.8 2.9 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.23 EIM92897.1 - 5.2e-45 154.2 23.1 4.2e-44 151.2 23.1 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIM92897.1 - 1.3e-08 35.3 7.3 1.3e-07 32.1 5.5 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIM92897.1 - 0.9 10.2 5.4 3.7 8.2 0.9 3.0 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 EIM92897.1 - 1.2 8.9 4.0 6.5 6.5 0.6 2.9 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal DAO PF01266.24 EIM92898.1 - 1.4e-35 123.6 0.0 1.6e-35 123.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM92898.1 - 0.00023 21.3 0.1 0.00047 20.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIM92898.1 - 0.0013 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EIM92898.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIM92898.1 - 0.099 11.7 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EIM92898.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 EIM92899.1 - 1.4e-62 211.3 0.1 1.7e-62 211.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIM92899.1 - 1.1e-45 155.6 0.9 1.3e-45 155.3 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIM92899.1 - 1.1e-07 31.9 0.7 1.6e-07 31.4 0.7 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIM92899.1 - 0.00038 19.9 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EIM92899.1 - 0.021 14.3 0.1 0.037 13.5 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DHFR_1 PF00186.19 EIM92899.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrofolate reductase p450 PF00067.22 EIM92900.1 - 1.9e-51 175.3 0.0 2.4e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF89 PF01937.19 EIM92901.1 - 9.8e-106 353.7 0.1 1.1e-105 353.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 L51_S25_CI-B8 PF05047.16 EIM92903.1 - 3e-12 46.3 0.1 4.6e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RhoGAP PF00620.27 EIM92905.1 - 0.00035 20.4 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Motile_Sperm PF00635.26 EIM92905.1 - 0.007 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD-like PF14874.6 EIM92905.1 - 0.04 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like tRNA-synt_2 PF00152.20 EIM92906.1 - 6.8e-78 261.9 0.1 9.5e-78 261.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIM92906.1 - 2.8e-07 30.4 0.6 5.2e-07 29.6 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EIM92906.1 - 0.0038 16.7 1.6 1.2 8.6 0.0 2.8 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) Mu-like_Pro PF10123.9 EIM92906.1 - 0.011 15.3 4.5 0.021 14.4 4.5 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein tRNA-synt_2b PF00587.25 EIM92906.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) TMEM119 PF15724.5 EIM92906.1 - 1.9 8.5 6.8 2.9 7.9 6.8 1.2 1 0 0 1 1 1 0 TMEM119 family RNA_pol_Rpc4 PF05132.14 EIM92906.1 - 2.1 8.8 7.1 3.9 7.9 7.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 OppC_N PF12911.7 EIM92907.1 - 0.23 11.4 2.4 0.38 10.8 2.4 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Peptidase_M56 PF05569.11 EIM92908.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Amidohydro_1 PF01979.20 EIM92912.1 - 2.1e-26 93.0 0.5 1.2e-22 80.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EIM92912.1 - 2e-05 24.2 7.6 5.6e-05 22.8 0.1 3.1 4 0 0 4 4 4 2 Amidohydrolase family CENP-T_C PF15511.6 EIM92913.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EIM92913.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EIM92913.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EIM92913.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIM92913.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EIM92913.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RibD_C PF01872.17 EIM92914.1 - 1.1e-32 113.5 0.0 3.7e-32 111.8 0.0 1.8 1 1 0 1 1 1 1 RibD C-terminal domain YTH PF04146.15 EIM92915.1 - 3e-53 180.2 0.4 3.2e-50 170.3 0.0 3.1 3 0 0 3 3 3 2 YT521-B-like domain RRM_1 PF00076.22 EIM92915.1 - 1.3e-05 24.9 0.0 0.027 14.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_28 PF00295.17 EIM92917.1 - 5.8e-45 153.8 7.6 5.8e-45 153.8 7.6 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EIM92917.1 - 1.4e-05 25.0 12.3 1.4e-05 25.0 12.3 2.9 1 1 2 3 3 3 2 Right handed beta helix region NTF2 PF02136.20 EIM92918.1 - 4.8e-14 52.9 0.0 6.1e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EIM92918.1 - 1.1e-07 31.9 0.0 1.5e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Pkinase PF00069.25 EIM92919.1 - 1.3e-75 254.2 0.0 1.7e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIM92919.1 - 5.8e-43 147.0 0.0 8.4e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EIM92919.1 - 6.4e-18 65.3 0.5 6.4e-16 58.9 0.5 3.2 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EIM92919.1 - 6.2e-12 45.4 0.2 6.2e-12 45.4 0.2 2.1 3 0 0 3 3 3 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EIM92919.1 - 1.7e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIM92919.1 - 0.00019 20.5 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EIM92919.1 - 0.00022 20.9 0.1 0.00043 19.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIM92919.1 - 0.015 15.2 1.0 0.25 11.3 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family YukC PF10140.9 EIM92919.1 - 0.12 11.2 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CBM_21 PF03370.13 EIM92921.1 - 2.4e-22 79.2 0.0 4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EIM92921.1 - 1.9e-05 25.1 0.0 3.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) F-box-like PF12937.7 EIM92922.1 - 1.4e-10 40.9 1.7 1.4e-10 40.9 1.7 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EIM92922.1 - 0.073 13.0 0.7 0.31 11.0 0.3 2.3 2 0 0 2 2 2 0 F-box domain DUF3145 PF11343.8 EIM92923.1 - 0.22 11.1 1.4 0.33 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) FlxA PF14282.6 EIM92923.1 - 9.3 6.3 10.0 21 5.2 9.1 2.1 1 1 1 2 2 2 0 FlxA-like protein Fungal_trans PF04082.18 EIM92924.1 - 9.6e-23 80.6 0.1 2.2e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIM92924.1 - 0.00054 20.0 13.2 0.001 19.1 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.23 EIM92925.1 - 1.3e-81 274.1 0.0 3.7e-81 272.7 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIM92925.1 - 4.4e-16 59.2 0.1 3.2e-13 49.9 0.0 2.9 3 0 0 3 3 3 2 Microtubule binding CLZ PF16526.5 EIM92925.1 - 0.053 13.9 2.9 0.19 12.1 2.9 2.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PBP1_TM PF14812.6 EIM92925.1 - 6.6 7.2 31.7 7.8 6.9 5.9 4.5 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spc7 PF08317.11 EIM92926.1 - 6.1e-78 261.8 11.1 6.1e-78 261.8 11.1 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EIM92926.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 DUF1664 PF07889.12 EIM92926.1 - 0.049 13.7 1.7 2.7 8.0 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LPP PF04728.13 EIM92926.1 - 0.078 13.4 2.5 2.3 8.7 0.1 3.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper TraF_2 PF13729.6 EIM92926.1 - 0.079 12.3 0.7 0.73 9.1 0.1 2.2 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein SKA2 PF16740.5 EIM92926.1 - 0.095 12.5 2.1 0.16 11.8 0.4 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Nab2 PF11517.8 EIM92926.1 - 0.11 12.8 0.0 3.7 7.9 0.0 2.7 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Baculo_F PF12259.8 EIM92926.1 - 0.28 9.6 2.3 0.43 9.0 2.3 1.2 1 0 0 1 1 1 0 Baculovirus F protein Hrs_helical PF12210.8 EIM92926.1 - 0.29 11.7 6.5 5.8 7.5 1.1 2.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MPS2 PF17060.5 EIM92926.1 - 0.35 10.1 4.4 0.65 9.2 4.4 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 YojJ PF10372.9 EIM92926.1 - 0.56 10.3 4.5 1.4 9.1 0.4 3.0 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Laminin_II PF06009.12 EIM92926.1 - 2.7 8.0 7.6 0.69 9.9 0.6 2.9 1 1 1 3 3 3 0 Laminin Domain II FapA PF03961.13 EIM92926.1 - 3.7 6.0 13.7 0.59 8.7 7.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A ADIP PF11559.8 EIM92926.1 - 4.7 7.3 12.7 0.61 10.2 1.4 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 EIM92926.1 - 6.2 7.0 10.0 9 6.5 0.9 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DIE2_ALG10 PF04922.12 EIM92928.1 - 5.1e-126 421.1 8.3 6.1e-126 420.9 8.3 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family RhodobacterPufX PF11511.8 EIM92928.1 - 0.059 13.0 1.8 0.16 11.6 1.8 1.8 1 0 0 1 1 1 0 Intrinsic membrane protein PufX OPT PF03169.15 EIM92929.1 - 2.8e-169 564.7 54.4 3.2e-169 564.5 54.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GMC_oxred_N PF00732.19 EIM92930.1 - 1.2e-43 149.6 0.0 1.6e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIM92930.1 - 3.2e-27 95.8 0.0 6.1e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EIM92930.1 - 0.00011 21.4 0.2 0.01 14.9 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EIM92930.1 - 0.00022 20.9 0.3 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIM92930.1 - 0.0045 17.2 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EIM92930.1 - 0.0085 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DUF2231 PF09990.9 EIM92931.1 - 0.32 11.5 9.6 0.25 11.8 0.9 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) Esterase_phd PF10503.9 EIM92932.1 - 9.2e-24 84.2 0.9 1.3e-23 83.6 0.9 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EIM92932.1 - 1.2e-12 47.5 7.7 6.3e-12 45.2 7.7 2.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EIM92932.1 - 1.1e-08 34.8 1.7 1.6e-08 34.3 1.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EIM92932.1 - 0.05 13.2 0.3 0.071 12.7 0.3 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EIM92932.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TauD PF02668.16 EIM92933.1 - 3.8e-56 190.9 0.6 4.7e-56 190.5 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OPT PF03169.15 EIM92934.1 - 2.2e-161 538.6 56.2 2.5e-161 538.4 56.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3272 PF11676.8 EIM92934.1 - 0.18 12.1 2.8 17 5.8 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Prp19 PF08606.11 EIM92935.1 - 4.5e-30 103.4 2.2 7.4e-30 102.7 2.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EIM92935.1 - 4.1e-11 43.3 3.7 0.27 12.2 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92935.1 - 1.5e-10 41.2 0.0 0.00016 21.9 0.0 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 EIM92935.1 - 2e-06 27.9 0.0 3.6e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 EIM92935.1 - 2.1e-05 24.2 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Frtz PF11768.8 EIM92935.1 - 0.012 13.9 0.0 0.031 12.6 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-NOSIP PF15906.5 EIM92935.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C2H2 PF00096.26 EIM92936.1 - 4.5e-07 30.0 2.2 0.011 16.1 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIM92936.1 - 4.8e-07 30.1 1.3 0.029 15.2 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EIM92936.1 - 0.00016 22.0 0.4 0.15 12.4 0.0 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EIM92936.1 - 0.0015 18.8 1.0 0.0047 17.3 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 EIM92936.1 - 0.5 10.2 2.4 3 7.7 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Abhydrolase_6 PF12697.7 EIM92937.1 - 1.8e-06 28.7 0.3 4.7e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIM92937.1 - 0.00082 19.1 0.2 0.0025 17.5 0.1 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Kinocilin PF15033.6 EIM92937.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinocilin protein Ser_hydrolase PF06821.13 EIM92937.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 EIM92937.1 - 0.12 12.1 0.4 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 EIM92937.1 - 0.13 11.5 0.0 8.5 5.6 0.0 2.5 2 1 0 3 3 3 0 Serine aminopeptidase, S33 DLH PF01738.18 EIM92937.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Myb_DNA-binding PF00249.31 EIM92938.1 - 8e-41 138.0 17.0 4.5e-14 52.4 1.3 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIM92938.1 - 1e-38 131.4 7.1 4.5e-16 58.8 0.1 4.2 2 1 2 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 EIM92938.1 - 4.4e-05 23.5 0.0 2.6 8.1 0.0 3.5 2 1 1 3 3 3 2 SLIDE zf-C2H2_4 PF13894.6 EIM92938.1 - 0.00048 20.7 7.6 0.13 13.1 1.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger SANT_DAMP1_like PF16282.5 EIM92938.1 - 0.00076 19.6 1.5 0.33 11.2 0.0 3.1 3 1 0 4 4 4 2 SANT/Myb-like domain of DAMP1 zf-C2H2 PF00096.26 EIM92938.1 - 0.0016 18.8 6.5 0.0071 16.7 1.9 3.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 EIM92938.1 - 0.0054 17.0 5.4 0.08 13.2 0.5 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Myb_DNA-bind_7 PF15963.5 EIM92938.1 - 0.0076 16.1 0.3 3.1 7.8 0.0 3.2 2 1 1 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 EIM92938.1 - 0.0098 16.0 2.9 14 5.9 0.3 3.3 1 1 2 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-H2C2_2 PF13465.6 EIM92938.1 - 3 8.4 16.3 0.25 11.8 2.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain WD40 PF00400.32 EIM92939.1 - 1.5e-30 104.7 15.1 9.9e-08 32.5 0.2 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIM92939.1 - 3.1e-09 37.0 0.1 0.13 12.6 0.1 4.5 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EIM92939.1 - 0.0011 18.6 0.0 0.077 12.6 0.0 2.7 2 1 1 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.16 EIM92939.1 - 0.0041 15.7 0.0 1.9 6.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EIM92939.1 - 0.034 13.1 2.2 6.3 5.6 0.1 3.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIM92939.1 - 0.16 11.9 0.5 5.4 7.1 0.2 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MCM PF00493.23 EIM92942.1 - 3.6e-95 317.3 0.1 5.2e-95 316.8 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIM92942.1 - 8.1e-34 116.2 0.0 1.4e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIM92942.1 - 1.3e-23 83.2 2.0 2.4e-23 82.4 2.0 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIM92942.1 - 2.3e-14 53.8 0.1 6.1e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIM92942.1 - 2.2e-08 33.8 0.5 1.4e-06 27.9 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EIM92942.1 - 0.0041 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4611 PF15387.6 EIM92942.1 - 0.011 15.9 5.1 0.029 14.6 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma54_activat PF00158.26 EIM92942.1 - 0.014 15.2 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EIM92942.1 - 0.076 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RXT2_N PF08595.11 EIM92942.1 - 0.33 11.0 3.5 0.78 9.8 3.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EIM92942.1 - 1 9.8 7.9 3 8.3 7.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Totivirus_coat PF05518.11 EIM92942.1 - 1.6 6.6 5.0 2.5 6.1 5.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF3500 PF12006.8 EIM92943.1 - 1.5e-90 303.7 0.0 1.7e-90 303.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) TTL PF03133.15 EIM92945.1 - 2.2e-43 148.5 0.0 3.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Thioredoxin PF00085.20 EIM92946.1 - 3.4e-26 91.2 0.0 3.9e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EIM92946.1 - 7.2e-09 35.5 0.0 7.8e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIM92946.1 - 5.5e-07 30.0 0.1 1.1e-06 29.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIM92946.1 - 8e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EIM92946.1 - 0.00036 20.3 0.1 0.0026 17.5 0.1 1.9 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 EIM92946.1 - 0.0023 18.1 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 EIM92946.1 - 0.005 16.2 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 EIM92946.1 - 0.055 13.3 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein KaiB PF07689.12 EIM92946.1 - 0.068 12.9 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 KaiB domain AhpC-TSA PF00578.21 EIM92946.1 - 0.07 13.0 0.1 0.094 12.6 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family DarA_N PF18788.1 EIM92946.1 - 0.084 13.0 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Defence against restriction A N-terminal AP3D1 PF06375.11 EIM92947.1 - 0.0024 18.1 1.9 0.11 12.7 0.8 2.4 2 0 0 2 2 2 2 AP-3 complex subunit delta-1 TPR_9 PF13371.6 EIM92947.1 - 0.012 15.8 0.2 0.088 13.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.25 EIM92948.1 - 1.5e-19 70.3 0.1 8.5e-19 67.8 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIM92948.1 - 1.4e-10 41.2 0.1 2.2e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM92948.1 - 0.029 14.3 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 KR domain CDC50 PF03381.15 EIM92949.1 - 4.2e-87 292.2 0.0 4.9e-87 292.0 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AAA_27 PF13514.6 EIM92950.1 - 0.11 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain KCNQ2_u3 PF16642.5 EIM92950.1 - 0.13 13.2 0.3 0.18 12.8 0.3 1.2 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 E1_DerP2_DerF2 PF02221.15 EIM92953.1 - 6.2e-25 88.2 0.1 7.7e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 ML domain RNase_T PF00929.24 EIM92954.1 - 8.4e-24 85.0 0.0 1.1e-23 84.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Ipi1_N PF12333.8 EIM92956.1 - 3.4e-21 75.7 0.5 7.9e-19 68.1 0.0 4.2 3 1 2 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation DNA_pol_A_exo1 PF01612.20 EIM92958.1 - 2.6e-10 40.3 0.0 3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DPBB_1 PF03330.18 EIM92959.1 - 8.9e-08 32.3 0.0 2.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase JAB PF01398.21 EIM92960.1 - 3.5e-15 56.0 0.0 7.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cation_efflux PF01545.21 EIM92961.1 - 8.1e-53 179.1 1.8 1.6e-52 178.2 1.8 1.4 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EIM92961.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Med5 PF08689.10 EIM92962.1 - 2.9e-12 45.3 0.1 5.8e-12 44.3 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit Med5 Cys_Met_Meta_PP PF01053.20 EIM92963.1 - 4.3e-25 88.0 0.0 6.1e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EIM92963.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II F-box PF00646.33 EIM92964.1 - 5.2e-08 32.6 2.1 5.2e-08 32.6 2.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EIM92964.1 - 1.4e-07 31.3 4.9 2.9e-07 30.3 1.0 2.3 2 0 0 2 2 2 1 F-box-like Anti-TRAP PF15777.5 EIM92964.1 - 0.88 9.6 9.1 33 4.5 3.6 3.0 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-C2H2_4 PF13894.6 EIM92964.1 - 4.9 8.3 5.7 53 5.1 0.1 3.7 2 1 1 3 3 3 0 C2H2-type zinc finger Cucumo_2B PF03263.13 EIM92964.1 - 5.2 7.6 5.9 0.46 11.0 0.4 1.9 2 0 0 2 2 2 0 Cucumovirus protein 2B Pex14_N PF04695.13 EIM92965.1 - 5.4e-21 75.9 2.4 5.4e-21 75.9 2.4 7.7 7 4 0 7 7 7 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GRIP PF01465.20 EIM92965.1 - 1.7e-16 59.8 0.6 4.8e-16 58.4 0.6 1.8 1 0 0 1 1 1 1 GRIP domain NPV_P10 PF05531.12 EIM92965.1 - 0.34 11.4 36.6 0.69 10.4 1.3 8.5 5 3 2 7 7 7 0 Nucleopolyhedrovirus P10 protein GTP_EFTU PF00009.27 EIM92966.1 - 4.6e-56 189.5 0.1 6.6e-56 188.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIM92966.1 - 2.9e-28 98.4 0.4 5.7e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EIM92966.1 - 5.4e-15 55.6 3.0 5.4e-15 55.6 3.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIM92966.1 - 8e-05 22.7 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIM92966.1 - 0.0086 16.0 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EIM92966.1 - 0.014 15.0 0.3 0.025 14.2 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EIM92966.1 - 0.042 13.6 0.6 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SPRY PF00622.28 EIM92967.1 - 1.2e-20 73.8 0.0 1.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Collagen_bind_2 PF12904.7 EIM92967.1 - 0.089 12.8 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase DUF2830 PF11125.8 EIM92967.1 - 0.13 12.3 2.2 0.28 11.2 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) Mito_carr PF00153.27 EIM92968.1 - 1.9e-58 194.4 1.3 3e-18 65.5 0.0 3.9 2 2 1 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 EIM92969.1 - 2.3e-15 56.6 0.0 4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 PX domain EzrA PF06160.12 EIM92969.1 - 0.059 11.5 0.4 0.16 10.1 0.8 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 EIM92969.1 - 0.14 12.5 3.9 0.37 11.3 3.7 1.8 2 0 0 2 2 2 0 Snapin/Pallidin DUF745 PF05335.13 EIM92969.1 - 4.8 6.9 9.1 0.79 9.4 3.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) SlyX PF04102.12 EIM92969.1 - 6.5 7.4 12.2 4.2 8.1 0.1 3.5 2 1 1 3 3 3 0 SlyX CBS PF00571.28 EIM92970.1 - 2e-27 95.4 3.5 4.6e-12 46.2 0.2 4.6 4 1 1 5 5 5 4 CBS domain Pil1 PF13805.6 EIM92971.1 - 3.7e-46 157.8 0.1 1e-45 156.4 0.0 1.7 2 0 0 2 2 2 1 Eisosome component PIL1 FAA_hydro_N_2 PF18288.1 EIM92971.1 - 0.13 12.7 0.0 0.52 10.8 0.0 2.0 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 IF4E PF01652.18 EIM92972.1 - 4e-50 169.7 0.0 5.1e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3251 PF11622.8 EIM92973.1 - 0.01 15.5 0.3 0.023 14.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) ABC1 PF03109.16 EIM92973.1 - 0.038 14.2 0.2 0.056 13.6 0.2 1.2 1 0 0 1 1 1 0 ABC1 family SMN PF06003.12 EIM92975.1 - 0.00015 21.1 3.6 0.00041 19.7 3.4 1.7 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 EIM92975.1 - 0.00026 21.0 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Tudor_3 PF18115.1 EIM92975.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain SelK_SelG PF10961.8 EIM92975.1 - 0.012 16.2 7.5 0.051 14.2 3.5 2.7 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Relaxase PF03432.14 EIM92975.1 - 0.049 13.2 3.3 0.072 12.7 3.3 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain RIO1 PF01163.22 EIM92976.1 - 1e-47 162.2 0.1 1.4e-47 161.7 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EIM92976.1 - 1.3e-34 118.2 0.1 4.2e-34 116.6 0.1 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 EIM92976.1 - 5.8e-11 42.8 0.3 0.00022 21.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EIM92976.1 - 2.7e-07 30.1 0.0 6.6e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_1 PF00583.25 EIM92977.1 - 1.6e-12 47.7 0.0 2.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIM92977.1 - 3.4e-07 30.3 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIM92977.1 - 3.5e-05 24.1 0.0 4.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIM92977.1 - 0.00028 20.8 0.0 0.00058 19.8 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EIM92977.1 - 0.0089 16.2 0.0 0.02 15.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain adh_short PF00106.25 EIM92978.1 - 1.1e-19 70.6 0.0 5.8e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIM92978.1 - 1.5e-11 44.3 0.0 1.2e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIM92978.1 - 1.7e-09 37.9 0.0 2.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 KR domain ESSS PF10183.9 EIM92979.1 - 1.4e-10 41.3 0.0 1.5e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GCV_H PF01597.19 EIM92980.1 - 1.7e-40 137.7 0.1 2.1e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EIM92980.1 - 0.00013 21.7 0.1 0.00022 21.0 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 EIM92980.1 - 0.00019 21.3 0.1 0.00031 20.7 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MFS_1 PF07690.16 EIM92981.1 - 4.5e-21 75.2 52.2 4.2e-11 42.4 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 EIM92982.1 - 1.3e-09 38.2 0.0 6.2e-09 36.1 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain HATPase_c_3 PF13589.6 EIM92982.1 - 0.055 13.3 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_61 PF03443.14 EIM92983.1 - 9.3e-59 198.8 0.4 1.7e-58 197.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 SR-25 PF10500.9 EIM92983.1 - 1 8.9 10.3 1.5 8.4 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EIM92983.1 - 2.1 6.3 9.8 2.6 6.0 9.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Period_C PF12114.8 EIM92983.1 - 3.6 7.1 12.8 6 6.4 12.8 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Cu-oxidase PF00394.22 EIM92984.1 - 1.3e-41 142.3 0.5 9.7e-40 136.3 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIM92984.1 - 1.6e-35 121.8 1.9 1.5e-33 115.5 0.3 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIM92984.1 - 1.1e-31 109.3 3.2 1.4e-28 99.3 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Ribosomal_L10 PF00466.20 EIM92985.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stereum_hirsutum_FP-91666_SS1-Stehi1/GCA_000264905.1_Stehi1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stereum_hirsutum_FP-91666_SS1-Stehi1/GCA_000264905.1_Stehi1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stereum_hirsutum_FP-91666_SS1-Stehi1/GCA_000264905.1_Stehi1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Stereum_hirsutum_FP-91666_SS1-Stehi1/GCA_000264905.1_Stehi1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 06:45:29 2019 # [ok]